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Search of human proteins with 203098098
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|203098098 shroom family member 3 protein [Homo sapiens]
(1996 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|203098098 shroom family member 3 protein [Homo sapiens] 4046 0.0
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 415 e-115
gi|118600967 shroom family member 4 [Homo sapiens] 247 9e-65
gi|31442420 shroom family member 1 [Homo sapiens] 110 1e-23
gi|153792074 proline rich 12 [Homo sapiens] 68 8e-11
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 66 3e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 60 2e-08
gi|61743948 abl-interactor 1 isoform d [Homo sapiens] 58 8e-08
gi|61743944 abl-interactor 1 isoform b [Homo sapiens] 58 8e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 57 2e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 5e-07
gi|61743942 abl-interactor 1 isoform a [Homo sapiens] 55 7e-07
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 55 9e-07
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 55 9e-07
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 55 9e-07
gi|55750053 atrophin-1 [Homo sapiens] 54 2e-06
gi|55750041 atrophin-1 [Homo sapiens] 54 2e-06
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 53 3e-06
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 53 3e-06
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 53 3e-06
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 53 3e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 52 4e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 52 4e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 52 4e-06
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 52 4e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 52 6e-06
gi|18959210 WIRE protein [Homo sapiens] 52 6e-06
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 52 8e-06
gi|61743946 abl-interactor 1 isoform c [Homo sapiens] 51 1e-05
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 4046 bits (10493), Expect = 0.0
Identities = 1996/1996 (100%), Positives = 1996/1996 (100%)
Query: 1 MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEG 60
MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEG
Sbjct: 1 MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEG 60
Query: 61 GKADTLSSKLQAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTG 120
GKADTLSSKLQAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTG
Sbjct: 61 GKADTLSSKLQAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTG 120
Query: 121 ASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQI 180
ASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQI
Sbjct: 121 ASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQI 180
Query: 181 SQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPA 240
SQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPA
Sbjct: 181 SQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPA 240
Query: 241 KSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMR 300
KSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMR
Sbjct: 241 KSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMR 300
Query: 301 QADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPS 360
QADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPS
Sbjct: 301 QADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPS 360
Query: 361 WSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSL 420
WSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSL
Sbjct: 361 WSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSL 420
Query: 421 GSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQV 480
GSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQV
Sbjct: 421 GSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQV 480
Query: 481 PQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLS 540
PQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLS
Sbjct: 481 PQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLS 540
Query: 541 PVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHP 600
PVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHP
Sbjct: 541 PVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHP 600
Query: 601 HSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKS 660
HSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKS
Sbjct: 601 HSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKS 660
Query: 661 AFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQV 720
AFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQV
Sbjct: 661 AFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQV 720
Query: 721 SYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCS 780
SYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCS
Sbjct: 721 SYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCS 780
Query: 781 VLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEP 840
VLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEP
Sbjct: 781 VLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEP 840
Query: 841 LGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPER 900
LGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPER
Sbjct: 841 LGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPER 900
Query: 901 EPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPR 960
EPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPR
Sbjct: 901 EPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPR 960
Query: 961 PSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSY 1020
PSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSY
Sbjct: 961 PSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSY 1020
Query: 1021 SEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQ 1080
SEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQ
Sbjct: 1021 SEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQ 1080
Query: 1081 FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLS 1140
FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLS
Sbjct: 1081 FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLS 1140
Query: 1141 SLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQ 1200
SLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQ
Sbjct: 1141 SLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQ 1200
Query: 1201 RGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG 1260
RGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG
Sbjct: 1201 RGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG 1260
Query: 1261 FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTL 1320
FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTL
Sbjct: 1261 FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTL 1320
Query: 1321 DHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPP 1380
DHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPP
Sbjct: 1321 DHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPP 1380
Query: 1381 YTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED 1440
YTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED
Sbjct: 1381 YTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED 1440
Query: 1441 SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPP 1500
SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPP
Sbjct: 1441 SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPP 1500
Query: 1501 HEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLD 1560
HEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLD
Sbjct: 1501 HEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLD 1560
Query: 1561 SEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSV 1620
SEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSV
Sbjct: 1561 SEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSV 1620
Query: 1621 HAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDK 1680
HAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDK
Sbjct: 1621 HAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDK 1680
Query: 1681 SLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAV 1740
SLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAV
Sbjct: 1681 SLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAV 1740
Query: 1741 SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEA 1800
SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEA
Sbjct: 1741 SMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEA 1800
Query: 1801 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVEN 1860
KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVEN
Sbjct: 1801 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVEN 1860
Query: 1861 VLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQD 1920
VLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQD
Sbjct: 1861 VLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQD 1920
Query: 1921 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDFIPKAGALALPPNLTSEPIPA 1980
YQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDFIPKAGALALPPNLTSEPIPA
Sbjct: 1921 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESLPSDFIPKAGALALPPNLTSEPIPA 1980
Query: 1981 GGCTFSGIFPTLTSPL 1996
GGCTFSGIFPTLTSPL
Sbjct: 1981 GGCTFSGIFPTLTSPL 1996
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 415 bits (1067), Expect = e-115
Identities = 379/1143 (33%), Positives = 517/1143 (45%), Gaps = 240/1143 (20%)
Query: 883 ARLLRSQSTFQLSSEPEREP---EWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGAT 939
A+L +S+ST L++ E E WR G + P + Y++ +K+AQ+RVL AT
Sbjct: 639 AKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQ---EGPLAGTYKDHLKEAQARVLRAT 695
Query: 940 SFRRRDLELGA------PVASRSWRPR--PSSAHVGLRSPEASASASPHTPRERHSVTPA 991
SF+RRDL+ + R P P GL P +S S PH PR
Sbjct: 696 SFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRI------- 748
Query: 992 EGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPE 1051
G RRR T EQK +SYSEPEKMNEVG+ P R E
Sbjct: 749 --------------GGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP------HQHPRTSE 788
Query: 1052 SSV---ADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQE 1108
+V ADR + FE K + Q+ AL + K + T+ C E
Sbjct: 789 DTVGTFADRWKFFEETSKPVPQ--------RPAQKQALHGIPRDKPERPRTAGRTCEGTE 840
Query: 1109 PGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPR 1168
P +++ L A + A S L PRR T AE Q + +
Sbjct: 841 PW-----SRTTSLGDSLNAHSAAEKAGTSDL---------PRRLGTF-----AEYQASWK 881
Query: 1169 DRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLER 1228
++ P E S +G+ SA+D+L+
Sbjct: 882 EQRK---------------------------------PLEARS----SGRCHSADDILDV 904
Query: 1229 S-DVLAGPVHV--RSRSSPATADKRQD--VLLGQDSGFGLVKDPCYLAGPGSRSLSCSER 1283
S D P HV RSRSSP+T +Q+ V L + +G DP G L + R
Sbjct: 905 SLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAG-----DP----GEPREELPSAVR 955
Query: 1284 GQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLV 1343
+E TPR + C+ G+ Q+ P PP T +
Sbjct: 956 AEEGQS------TPRQADAQCRE-----------GSPGSQQHPPSQKAPNPP---TFSEL 995
Query: 1344 TDTRAAPLTPI-GTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRG 1402
+ R AP P G +P Y + T PA + GPR
Sbjct: 996 SHCRGAPELPREGRGRAGTLPRDYRYSEEST---------PADL------------GPRA 1034
Query: 1403 CEGDGPEHG-------VEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSA------- 1448
P H V + PQ PPP + + D P ++
Sbjct: 1035 QSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPF 1094
Query: 1449 --PDFANLKHYQKQQSL---PSLCSTSDP-DTPL------GAPSTPGRISLRISESVLRD 1496
P A+L Y + SL PS+ S++ P DTP G+ G S + E++L
Sbjct: 1095 PTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALL-- 1152
Query: 1497 SPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCE 1556
PP + + AT + P P P + + P+ D+ T E
Sbjct: 1153 -PPKQQHLRLQT--------ATMETSRSPSPQFAPQKLTDKPPLLIQDE-----DSTRIE 1198
Query: 1557 AQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPS 1616
+D+ N K+ + H Q+LA + E
Sbjct: 1199 RVMDN----------NTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIK 1248
Query: 1617 FMSVHAQLAGSL------GGQP-APIQTQSLSHDPVSGTQGLEKKVSPDP---------Q 1660
+S Q G +P AP + Q P+ EK P +
Sbjct: 1249 TLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKE 1308
Query: 1661 KSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAI 1720
K+ ED+++E LA+EIV +DKSLADILDP ++KTTMDLMEG+FP+D +LL+E +RK +
Sbjct: 1309 KTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLL 1368
Query: 1721 QRTVSSSGCEGKRNEDK--EAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQA- 1777
+ S E ++ E AVS+ N YYS SAPKAELL K+K++ + EE+
Sbjct: 1369 PKIPSPRSTEERKEEPSVPAAVSLATNS-TYYSTSAPKAELLIKMKDLQEQQEHEEDSGS 1427
Query: 1778 ----DVNEKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDK 1833
D++ KK ELI S++ KL+ L+EA+ SLL D++ N LG EVEA++ +CKP+EFDK
Sbjct: 1428 DLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDK 1487
Query: 1834 YRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARE 1893
+RMFIGDLDKVVNLLLSLSGRLARVEN L+ L + AS +R SL EK+++L QHEDA+E
Sbjct: 1488 FRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKE 1547
Query: 1894 LKENLDRRERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLL 1953
LKENLDRRER+V ILANYLSEE L DY+HFVKMKS L+IEQR+L+DKI LG+EQ+KCLL
Sbjct: 1548 LKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLL 1607
Query: 1954 ESL 1956
+SL
Sbjct: 1608 DSL 1610
Score = 186 bits (473), Expect = 2e-46
Identities = 148/406 (36%), Positives = 190/406 (46%), Gaps = 103/406 (25%)
Query: 13 ATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQA 72
A + A GR + E L GGAPWGFTLKGG EHGEPL+I+K+EEG KA + KL A
Sbjct: 14 AEAETRAADGGRLV--EVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAV-DKLLA 70
Query: 73 GDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTS 132
GDE+V IN++ LS R+EA+ LVKGS+KTL+LVV+
Sbjct: 71 GDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK------------------------- 105
Query: 133 GPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQS 192
RRSE RPHSWH TK + P+ + + P W
Sbjct: 106 -------------------RRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGR 146
Query: 193 YHSSSSTSDL-SNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSH 251
+H+SSS+ DL S+++ L+R+ D SS GS++SL+ +P LS AKS SID L
Sbjct: 147 HHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLD----HPSSRLSVAKSNSSIDHLGS 202
Query: 252 FHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMRQADIRYVKTVY 311
H+KRDSAY SFSTSSS P +S + S S +N GL E RQ
Sbjct: 203 -HSKRDSAYGSFSTSSST---PDHTLSKADTS-SAENILYTVGLWEAPRQG--------- 248
Query: 312 DTRRGVSAEYEVNSSALLLQGREARASANGQG-YDKWSNIP------RGKGVPP------ 358
GR+A+A+ + QG +K S P GKG P
Sbjct: 249 --------------------GRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEP 288
Query: 359 ----PSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRER 400
P S P P P PP RSDS+AA + E+
Sbjct: 289 KLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEK 334
Score = 32.7 bits (73), Expect = 3.7
Identities = 42/166 (25%), Positives = 58/166 (34%), Gaps = 41/166 (24%)
Query: 1525 PLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSE-------------DPEGPR--- 1568
P PPPPPPP + D F H + + SE P G R
Sbjct: 311 PSSPPPPPPPLRS------DSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPE 364
Query: 1569 ---PSFNKLSKVTIARERHMPGA---AHVVGS-----QTLASRLQTSIKGSEA------- 1610
+ ++ + PG AH GS +SRLQ S+ S+
Sbjct: 365 LTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPH 424
Query: 1611 ESTPPSFMSVHAQL-AGSLGGQPAPIQTQSLSHDPVSGTQGLEKKV 1655
P S H+ L A SLG +P Q+ S V G ++K+
Sbjct: 425 SGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKL 470
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 247 bits (630), Expect = 9e-65
Identities = 130/220 (59%), Positives = 173/220 (78%), Gaps = 8/220 (3%)
Query: 1748 AYYSVSAPKAELLNKIKEMP--AEVNEEEEQAD--VNEKKAELIGSLTHKLETLQEAKGS 1803
AYY++S KAELLNK+K+ P AE+ EE+ D + +KK +LI S++ KL L+EA+
Sbjct: 1275 AYYNISVAKAELLNKLKDQPEMAEIGLGEEEVDHELAQKKIQLIESISRKLSVLREAQRG 1334
Query: 1804 LLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLS 1863
LL DI N+ALGEEVEA + +CK NEF+KY +F+GDLDKVVNLLLSLSGRLARVEN L+
Sbjct: 1335 LLEDINANSALGEEVEANLKAVCKSNEFEKYHLFVGDLDKVVNLLLSLSGRLARVENALN 1394
Query: 1864 GLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQLQDYQH 1923
+ +A N+E+ L EK++ L GQ DA+ELKE++DRRE++V G+++ YL ++QLQDYQH
Sbjct: 1395 SIDSEA-NQEKLVLIEKKQQLTGQLADAKELKEHVDRREKLVFGMVSRYLPQDQLQDYQH 1453
Query: 1924 FVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESL---PSDF 1960
FVKMKS L+IEQR+L++KIKLG+EQ+KCL ESL PS+F
Sbjct: 1454 FVKMKSALIIEQRELEEKIKLGEEQLKCLRESLLLGPSNF 1493
Score = 144 bits (363), Expect = 9e-34
Identities = 100/248 (40%), Positives = 131/248 (52%), Gaps = 57/248 (22%)
Query: 23 GRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEV 82
G + Y+ L+GGAPWGFTLKGGLEH EPL +SK+E+GGKA LS K++ GDE+V+IN
Sbjct: 6 GSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKA-ALSQKMRTGDELVNINGT 64
Query: 83 TLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWS 142
L SR+EA+ L+KGS++ L+L+VR
Sbjct: 65 PLYGSRQEALILIKGSFRILKLIVR----------------------------------- 89
Query: 143 GGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQSYHSSSSTSDL 202
RR+ P RPHSWH K E P+A+ + + S+HS +TSD+
Sbjct: 90 ---------RRNAPVSRPHSWHVAKLLEGCPEAA---TTMHFPSEAFSLSWHSGCNTSDV 137
Query: 203 SNYDHAYLRR-SPDQCSSQGSMESLE-PSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAY 260
R S ++ SS GSMESLE P A HL P IDQ + + N+RDSAY
Sbjct: 138 CVQWCPLSRHCSTEKSSSIGSMESLEQPGQATYESHLLP------IDQ-NMYPNQRDSAY 190
Query: 261 SSFSTSSS 268
SSFS SS+
Sbjct: 191 SSFSASSN 198
Score = 32.3 bits (72), Expect = 4.8
Identities = 38/160 (23%), Positives = 56/160 (35%), Gaps = 32/160 (20%)
Query: 1285 QEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQAS-----------RTPCPR 1333
+ +LP+ ++ P S + SS S+C +L + AS + P R
Sbjct: 171 ESHLLPIDQNMYPNQRDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAPSGR 230
Query: 1334 PPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGR-QPLPPYTPAMMHRSNGH 1392
P +A T G T LTP + + S GY S + R P PP + S
Sbjct: 231 PNVAETSGGSRRTNGGHLTP-SSQMSSRPQEGYQSGPAKAVRGPPQPPVRRDSLQASRAQ 289
Query: 1393 TLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAK 1432
L G ++R S P P P + K
Sbjct: 290 LL-------------------NGEQRRASEPVVPLPQKEK 310
>gi|31442420 shroom family member 1 [Homo sapiens]
Length = 847
Score = 110 bits (275), Expect = 1e-23
Identities = 163/698 (23%), Positives = 259/698 (37%), Gaps = 104/698 (14%)
Query: 1311 SVPSECPGTLDHQRQAS-------------RTPCP----RPPLAGTQGLVTDTRAAPLTP 1353
+VP+ P T H R AS R P P R PLA Q + L
Sbjct: 174 TVPARPPAT--HPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDR 231
Query: 1354 IGT---PLPSAIPSGYCSQDGQTGRQPLPPYTPAMM----HRSNGHTLTQPPGPRGCEGD 1406
+G P + CS G G +PL PA+ H TQP G +
Sbjct: 232 VGRGGGPARECLGEA-CSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSG 290
Query: 1407 GPEHGVEEGTRKRVSLPQWPPPSRAKWAHA-------AREDSLPEESSAPDFANLKHYQK 1459
+ G + P SR++ A ++P + P A
Sbjct: 291 SLKLG-----------DAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLF 339
Query: 1460 QQSLPSLCSTSDPDT--PLGAP-STPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPK 1516
Q L + P P S+P R+SE+ + + P DEVF+ +
Sbjct: 340 QTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLP--SLPDEVFLEE---- 393
Query: 1517 ATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSK 1576
+P + PP P SQ PP H S+ P G + +
Sbjct: 394 ---APLVR-MRSPPDPHASQG---------PPASVHA-------SDQPYGTGLG-QRTGQ 432
Query: 1577 VTIARE---RHMPGAAHV----------VGSQTLASRLQTSIKGSEAESTPPSFMSVHAQ 1623
VT+ E PG A VG S T + P+ ++ +
Sbjct: 433 VTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPP 492
Query: 1624 LAGSLGG-QPAPIQTQSLSHDPVSG----TQGLEKKVSPDPQKSSEDIRTEALAKEIVHQ 1678
A +P P LS + G T P + + E L +E+
Sbjct: 493 TAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQELARL 552
Query: 1679 DKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKE 1738
D SL D L + + L++GL P L + + R A + + +
Sbjct: 553 DPSLCDPLASQPSPEPPLGLLDGLIP----LAEVRAAMRPACGEAGEEAASTFEPGSYQF 608
Query: 1739 AVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQ 1798
+ + L+ PA + + + + + P + KK EL L L+ L
Sbjct: 609 SFTQLL--PAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQKMLQDLH 666
Query: 1799 EAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARV 1858
+ L + + +EA + + C P E +++ F+ DL++V+ LLL L RLARV
Sbjct: 667 TEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLGSRLARV 726
Query: 1859 ENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQL 1918
L+ D+ +E ++ ++L Q EDA+ELKE++ RRER V +L L E+L
Sbjct: 727 RRALARAASDSDPDE-----QRLRLLQRQEEDAKELKEHVARRERAVREVLVRALPVEEL 781
Query: 1919 QDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESL 1956
+ Y + K+ +L +QR LD++I+L Q+Q+ + + L
Sbjct: 782 RVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL 819
Score = 77.4 bits (189), Expect = 1e-13
Identities = 147/593 (24%), Positives = 214/593 (36%), Gaps = 164/593 (27%)
Query: 875 GRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSP------ESPLLDA---------- 918
G GP PDA L S + + P+ + PG+P +PLL A
Sbjct: 69 GPGPAPPDAALCTSPRP-RPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
Query: 919 -------PFSRA-YRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRP-RPSSAHVGLR 969
P SRA YR ++ AQ RVL TSF+R++L + P R P RP + H
Sbjct: 128 AVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATH---- 183
Query: 970 SPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEV 1029
P +++ + P EG+ AR PA R L +Q+K +SEP K++ V
Sbjct: 184 -PRSASLSHP----------GGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRV 232
Query: 1030 GIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADY 1089
G GP R + G+ACS+ L GPE +FQ ALA +
Sbjct: 233 G-------RGGGPARECL-----------------GEACSSSGLPGPEPLEFQHPALAKF 268
Query: 1090 IQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQP 1149
+ G P + S+ S L+ G A
Sbjct: 269 EDHEVGWLPETQPQGSM--------NLDSGSLKLGDA----------------------- 297
Query: 1150 RREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGT----RGTQRGDET 1205
+ A R RS+S G LG G +GGT + +G ET
Sbjct: 298 -------------FRPASRSRSAS---GEVLGS-------WGGSGGTIPIVQAVPQGAET 334
Query: 1206 PREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVK 1265
PR ++ + L ++ + P + +SSPA +++R + +
Sbjct: 335 PRP-------LFQTKLSRFLPQKEAAVMYPAEL-PQSSPADSEQRVSETCIVPAWLPSLP 386
Query: 1266 DPCYL-AGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGC-KAIGDSSVPS-----ECPG 1318
D +L P R S + + P H + + G+G + G +VP+ ECPG
Sbjct: 387 DEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPG 446
Query: 1319 TLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTP---LPSAIPSGYCSQDGQTGR 1375
T A C G G V +R TP GT +P+ P+G +
Sbjct: 447 T------AGADDC----WQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAE 496
Query: 1376 QPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEH--GVEEGTRKRVSLPQWP 1426
L PA G G + GP H + GT + S P WP
Sbjct: 497 SDLLKPVPA-----------DALGLSGNDTPGPSHNTALARGTGQPGSRPTWP 538
Score = 38.9 bits (89), Expect = 0.051
Identities = 67/271 (24%), Positives = 100/271 (36%), Gaps = 59/271 (21%)
Query: 223 MESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRER 282
ME+L P G SPA ST S+D L H + DSAYSSFS +S G R +
Sbjct: 1 MEALGPGGD----RASPASSTSSLD-LWHLSMRADSAYSSFSAASG-------GPEPRTQ 48
Query: 283 SGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQ 342
S D + D YV+ V+ A L R + +
Sbjct: 49 SPGTDL----------LPYLDWDYVRVVW------GGPGPAPPDAALCTSPRPRPAVAAR 92
Query: 343 GYDKWSNIPRGKGVPPPSWSQQCP--SSLETATDNLPPKVGAPLPPARSDSYAAFRHRER 400
+ + +P G P P Q P +L + V P PPA S AA+R R +
Sbjct: 93 SGPQPTEVP---GTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPA---SRAAYRQRLQ 146
Query: 401 PSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQ 460
+ Q+R+ R ++ F ++L L + P +P + + A
Sbjct: 147 GA------QRRVLR---------ETSFQRKELRMSLPARLRPTVPARPPATHPRSA---- 187
Query: 461 PLLPTSIYPVPSLEPHFAQVPQPSVSSNGML 491
+ +P EP ++ P P + G L
Sbjct: 188 ----SLSHPGGEGEPARSRAPAPGTAGRGPL 214
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 68.2 bits (165), Expect = 8e-11
Identities = 72/262 (27%), Positives = 91/262 (34%), Gaps = 49/262 (18%)
Query: 1342 LVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPR 1401
L + R PL G P + P G QP PP TPA+ H P P
Sbjct: 1289 LKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPH----------PPPS 1338
Query: 1402 GCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQ 1461
G G G E + P P R ++LP SS + + K+ Q+
Sbjct: 1339 GAFGLGGALEAAESEGLGLGCPS--PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQE 1396
Query: 1462 SLPSLCSTSDPDTPLGAP---STPGRISLRISESVLRDSPPP---------HEDYEDEVF 1509
S+ S S D D PL P STP L + +V PPP + E +
Sbjct: 1397 SISSAISALD-DPPLAGPKDTSTPDGPPLAPAAAV--PGPPPLPGLPSANSNGTPEPPLL 1453
Query: 1510 VRDPHPKATSSPTFEPLPPP----------------------PPPPPSQETPVYSMDDFP 1547
P P +PT +P PPP PPPPP P +M P
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Query: 1548 PPPPHTVCEAQLDSEDPEGPRP 1569
PPPP E+P P P
Sbjct: 1514 PPPPPAAAPLAAPPEEPAAPSP 1535
Score = 42.4 bits (98), Expect = 0.005
Identities = 72/287 (25%), Positives = 91/287 (31%), Gaps = 48/287 (16%)
Query: 1300 GGSGCKAIGDSSVPSECPGTLDHQRQASRT-------PCPRPP-LAGTQGLVTDTRAAPL 1351
G G K GD S PG +R P PP +G GLV + AA
Sbjct: 611 GAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADA 670
Query: 1352 TPI-----GTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGD 1406
+ G P P +D Q T A + L G +
Sbjct: 671 SKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKK 730
Query: 1407 GPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPS- 1465
GPE G E S+ + ++ A + P ++ Q Q P
Sbjct: 731 GPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTA----------QSTQPTPHG 780
Query: 1466 -LCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFE 1524
L PD PL P P ++ SVL +P P +V V P
Sbjct: 781 LLLEAGGPDLPLVLPPPPPQLL----PSVLSHAPSPSPS-ASKVGVHLLEPATRDGA--- 832
Query: 1525 PLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSE--DPEGPRP 1569
P PPPPPPP PPPP EA L S +P P P
Sbjct: 833 PQPPPPPPP-------------PPPPMPLQLEAHLRSHGLEPAAPSP 866
Score = 36.2 bits (82), Expect = 0.33
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Query: 1525 PLPPPPPPPPSQETPVYSMDDFPP-PPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIAR-E 1582
P P P PPP ETP + + PP P T E P RP + K + R E
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE 1751
Query: 1583 RHMPGAAHVVGSQTLASR 1600
R + G G QT R
Sbjct: 1752 RPLRGERATSGRQTRPER 1769
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 66.2 bits (160), Expect = 3e-10
Identities = 228/1070 (21%), Positives = 350/1070 (32%), Gaps = 163/1070 (15%)
Query: 565 NEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSE 624
+E ++ ++H +P + S ++K S + P S + ++ + + +SR
Sbjct: 220 SESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS 279
Query: 625 PWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGT 684
+ H L R G+ G+ ++ +S Q R SS E
Sbjct: 280 --RSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ-------RPSSPETATK- 329
Query: 685 QEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQVSYPRPEGRT-------GASASFNS 737
+P+ K +D K+A +R + P P T G S +
Sbjct: 330 -------QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLA 382
Query: 738 TDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQR 797
T P +EP P + + R P P KVS+ S +
Sbjct: 383 TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK 442
Query: 798 PSVGGSGFGHNYRPHRTVSTSSTSGNDF----EETKAHIRF------------------S 835
P+ HR +S+S TS N + K+H S
Sbjct: 443 PAPAPGS-------HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS 495
Query: 836 ESAEPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLS 895
S P G ++ + + S Q G+ S R PQRP R+ S
Sbjct: 496 RSRTPTKRGHSRSRSPQWR-RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS 554
Query: 896 SEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASR 955
R P + P R S A+ R T RRR R
Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
Query: 956 SWRPRPSSAHVGLRSP--EASASASP---------HTPRER---HSVTPAEGDLARPVPP 1001
S P+ RSP S S SP TP R S TPA +R P
Sbjct: 615 SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTP 674
Query: 1002 AARRGARRRLTPEQKKRSYSEPEKMNEV---GIVEEAEPAPLGPQRNGMRFPESSVADRR 1058
A R G R TP ++ RS S + +V PQR G S ++
Sbjct: 675 ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 1059 RLFERDGKACSTLSLSGPELKQ----FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRE 1114
R +R + S S PE+K+ ++S + K R + S P P ++
Sbjct: 735 RTSQRRSR-----SNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP-KQ 788
Query: 1115 RAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDRSSSF 1174
++Q+ P + GS A S R P + R ++ P ++T SSS
Sbjct: 789 KSQT----PPRRSRSGSSQPKAKS----RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Query: 1175 AGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAG 1234
+ G R ++ + TP+ S + + + + S +
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSV-----TPQRRSCFESSPDPELKSRTPSRHSCSGSS 895
Query: 1235 PVHVRSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSE-------RGQEE 1287
P V+S + P + R + P + GS S S S R
Sbjct: 896 PPRVKSSTPPRQSPSRSS---SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 1288 MLPLFH---HLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTP------CPRPPLAG 1338
+ P + L PR+ SG + D+ V E P H S P P P L+G
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSS-PDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSG 1011
Query: 1339 TQGLVTDTRAAPLTPIGTP--------LPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSN 1390
++ ++ P + S+ P G S G + Q + HRS+
Sbjct: 1012 SKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGE-SYFGVSSLQLKGQSQTSPDHRSD 1070
Query: 1391 GHTLTQPPGPRGCEGDGP-----EHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEE 1445
T P R + P +G R R S P SR+ R+D E
Sbjct: 1071 ----TSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRS----PIRQDR-GEF 1121
Query: 1446 SSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYE 1505
S++P + +QS S+S P + + S G+ L +ES + + PP ED
Sbjct: 1122 SASPMLKS--GMSPEQSRFQSDSSSYP--TVDSNSLLGQSRLETAESKEKMALPPQED-- 1175
Query: 1506 DEVFVRDPHPKATSSP-----TFEPLPPPPPPPPSQETPVYSMDDFPPPP 1550
AT+SP F P P P E+ + D PP
Sbjct: 1176 -----------ATASPPRQKDKFSPFPVQDRP----ESSLVFKDTLRTPP 1210
Score = 56.6 bits (135), Expect = 2e-07
Identities = 219/1022 (21%), Positives = 327/1022 (31%), Gaps = 177/1022 (17%)
Query: 725 PEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEK 784
P ++G+ +S P+P P S +SS G RGP P +S+ + P +
Sbjct: 1612 PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKG-RGPSPEGSSSTESSPEHPPKSRTARR 1670
Query: 785 VS------KFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESA 838
S K + R +R S R R ++S+S T R S S
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730
Query: 839 EPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEP 898
E+ + + + R + S RG QR +R R E
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR---------EK 1781
Query: 899 EREPEWRDRPGSPESPLLDAPFSRAYR------------NSIKDAQSRVLGATSFRRRDL 946
R RDR GS +S SR+ +S A+ +S RRR
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
Query: 947 ELGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRG 1006
P + + R R S A + + ASP T R S TP +RR
Sbjct: 1842 SRTPPTSRKRSRSRTSPA----PWKRSRSRASPATHRRSRSRTPL----------ISRRR 1887
Query: 1007 ARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGK 1066
+R R +P ++RS S + +P+ +R+ R P RRR R
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRR---RSRSRASPVSRRRSRSRTPP---VTRRRSRSRT-- 1939
Query: 1067 ACSTLSLSGPELKQFQQSALADYIQRKTGKR-PTSAAGCSLQEPGPLRERAQSAYLQPGP 1125
P ++ +S +R++ R P S P+ R + P
Sbjct: 1940 ---------PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVT 1990
Query: 1126 AALEGSGLASAS-SLSSLREPSLQPRREATLLPATV-----AETQQAPRDRSSSFAGGRR 1179
S + + S R + RR + P + + T PR RS S +
Sbjct: 1991 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS---P 2047
Query: 1180 LGERRRGDLLSGANG-GTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHV 1238
L RRR + G R R R S+ G+ + +S SA R+ H
Sbjct: 2048 LAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN-------HS 2100
Query: 1239 RSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPR 1298
SR+ P + + + S D C R + PL TP
Sbjct: 2101 GSRTPPVALNSSRMSCFSRPSMSPTPLDRC--------------RSPGMLEPLGSSRTPM 2146
Query: 1299 WGGSGCKAIGDSSVPSECPGTLDHQRQA-----------------SRTPCPRPPLAGTQG 1341
S + G S + P DHQR + S PP G
Sbjct: 2147 ---SVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAG 2203
Query: 1342 L------------VTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPL--------PPY 1381
L + R AP + + +P+A + +T P P
Sbjct: 2204 LAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPA 2263
Query: 1382 TPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE--GTRKRVSL--------------PQW 1425
A M+ ++ T P + P G R +L +
Sbjct: 2264 AAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANY 2323
Query: 1426 PPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPL--GAPSTPG 1483
P SR A A+ P + A N+ + +L TS P GA T
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383
Query: 1484 RISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSM 1543
R+ L E V + PP D R P P A S P P + P S+
Sbjct: 2384 RVPLSAYERVSGRTSPP---LLDRARSRTP-PSAPSQSRMTSERAPSPSSRMGQAPSQSL 2439
Query: 1544 DDFPPPPPHTVCEAQLDSEDPEGPRPS-FNKLSKVTIARERHMPGAAHVVGSQTLASRLQ 1602
PP + P P PS F+ S+ IA+ V GSQ+L+S
Sbjct: 2440 --LPPA-----------QDQPRSPVPSAFSDQSRCLIAQ------TTPVAGSQSLSSGAV 2480
Query: 1603 TSIKGSEAESTPPSFMSVHAQ-LAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQK 1661
+ S + +SV A + S G+P P T + ++ Q +++ S
Sbjct: 2481 ATTTSSAGDHN--GMLSVPAPGVPHSDVGEP-PASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 1662 SS 1663
SS
Sbjct: 2538 SS 2539
Score = 51.6 bits (122), Expect = 8e-06
Identities = 218/1072 (20%), Positives = 332/1072 (30%), Gaps = 204/1072 (19%)
Query: 679 ELGRGTQEGYPGGRPTCA-------VNTKAEDPGRKAAPDLGSHLD----------RQVS 721
++ G +E PG RP +N K + R A S++D R+
Sbjct: 102 DVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAK 161
Query: 722 YPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSV 781
P PE S S+ P GRR + K H S
Sbjct: 162 QPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221
Query: 782 LEKV----------SKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEET--- 828
E SK + +++ +R S + + R HR+ S S S +D +
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDKKRKR-SRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280
Query: 829 ----KAHIRFSESAEPL------GNGEQHFKNGELKL-------EEASRQPCGQQLSGGA 871
K H P G G+ F E A++QP
Sbjct: 281 SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340
Query: 872 SDSGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKDA 931
+ RP RS + P P +R G PL P S+ N +A
Sbjct: 341 DKKEKSATRPSPSPERSSTG---PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA 397
Query: 932 QSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEAS-----ASASPHTPR--- 983
RD +P S P+ SS+ SP+ + AS+SP +P+
Sbjct: 398 SPT---------RDR---SPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445
Query: 984 -------------------------ERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKR 1018
+ HS TP+ P A+RG R TP ++
Sbjct: 446 APGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505
Query: 1019 SYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPEL 1078
S S + + + +R R P+ R R +R G++ S
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSAR------- 558
Query: 1079 KQFQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASS 1138
+ ++ R + G S R R++S PA
Sbjct: 559 ------------RGRSHSRSPATRGRSRSRTPARRGRSRSRT----PARRRSRSRTPTRR 602
Query: 1139 LSSLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERR-RGDLLSGANGGTR 1197
S R P+ + R + + T+ R RS S + RR G R R G +
Sbjct: 603 RSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662
Query: 1198 GTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPAT----ADKRQDV 1253
+RG R P+ R+G+S S P RSRS + R
Sbjct: 663 PARRGRSRSRTPAR---RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQ 719
Query: 1254 LLGQDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVP 1313
G+ K+ + SRS S E + + S ++ SS
Sbjct: 720 RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI-------------SSRRSRSLSSPR 766
Query: 1314 SECPGTLDHQRQAS-RTPCPR-----PPLAGTQGLVTDTRAAPLTPIGTPLPSAIP---- 1363
S+ L +R S +PCP+ PP G + +A TP S+ P
Sbjct: 767 SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGS-SQPKAKSRTPPRRSRSSSSPPPKQ 825
Query: 1364 -SGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQP------PGPRGCEGDGPEHGVEEGT 1416
S S+ + P P R T Q P R C P+ ++ T
Sbjct: 826 KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRT 885
Query: 1417 RKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPD------FANLKHYQKQQSLPSLCSTS 1470
R S PP R K + R+ P SS+P + + S PS +
Sbjct: 886 PSRHSCSGSSPP-RVKSSTPPRQS--PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVT 942
Query: 1471 DPDTPLGAPSTP------GRISLRISES-------VLRDSPPPHEDYEDEVFVRDPHPKA 1517
TP + S R+ R S S ++ PP + + + P+PK
Sbjct: 943 SRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI---SPYPKV 999
Query: 1518 TSS----PTFEPLPPPPPPPPSQETPVYS----------MDDFPPPPPHTVCEAQLDSED 1563
+ P+ P P S+++ V S + PP + L +
Sbjct: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG 1059
Query: 1564 PEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPP 1615
P + R+ H S +L S+ QTS KG + S+ P
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQSHSE-------SPSLQSKSQTSPKGGRSRSSSP 1104
Score = 48.1 bits (113), Expect = 8e-05
Identities = 174/860 (20%), Positives = 261/860 (30%), Gaps = 127/860 (14%)
Query: 855 LEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPEREPEW-RDRPGSPES 913
L + S P LSG + P+ P R +S S EP+ P+ R R SP S
Sbjct: 1447 LRDGSGTPSRHSLSGSSPGMKDIPRTPS----RGRSECDSSPEPKALPQTPRPRSRSPSS 1502
Query: 914 PLLDAPF---SRAYRNSIKDAQSRVLGATSFRRR---------DLELGAPVASRSWRPRP 961
P L+ R S + + T +R D++ A RS
Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS 1562
Query: 962 SSAHVGLRSPEASASASPHTP-----------RERHSVTPAEGDLARPVP---------- 1000
+ R+P S S +P R R +P D R P
Sbjct: 1563 PDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSP 1622
Query: 1001 ----PAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVAD 1056
PA R RR + K PE + E P +R PE
Sbjct: 1623 EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS 1682
Query: 1057 RRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQEPG--PLRE 1114
R R ++ L+ ++ + ++ + + +T R + S EP
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSS 1742
Query: 1115 RAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDRSSSF 1174
R + + P G + + L+ + RRE T T++ R SS
Sbjct: 1743 RRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT------RTTRRRDRSGSSQS 1796
Query: 1175 AGGRRLGERRRGDLLSGANGGT--------------------RGTQRGDETPRE------ 1208
RR R R + GG+ RG R T R+
Sbjct: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856
Query: 1209 -PSSWGARAGKSMSAEDLLERSDV-LAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVKD 1266
P+ W ++ A RS L RSR+SP + + +
Sbjct: 1857 SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916
Query: 1267 PCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQA 1326
P SR+ + R P T R S + S P + ++
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTP----TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS 1972
Query: 1327 SRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMM 1386
+P R VT R+ T T S + ++ R P PA+
Sbjct: 1973 RTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP-----PAIR 2027
Query: 1387 HRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRV--------SLPQWPPPSRAKWAHAAR 1438
RS T P PR + +R R SL + PP R + A +
Sbjct: 2028 RRSRSRT---PLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084
Query: 1439 ED----SLP------EESSAPDFANLKHYQKQQSLPSL-------CSTSDPDTPLGAPST 1481
D + P S P A S PS+ C + PLG+ T
Sbjct: 2085 SDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRT 2144
Query: 1482 PGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPL---PPPPPPPPSQET 1538
P + + S++ D P P V + H ++ + + PPP S
Sbjct: 2145 PMSVLQQAGGSMM-DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAG 2203
Query: 1539 PVYSMDDFPPPPP----HTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGS 1594
M P P P T A L S P + N S AR +P A ++ S
Sbjct: 2204 LAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLAS----ARTPAIPTAVNLADS 2259
Query: 1595 QTLASRLQTSIKGSEAESTP 1614
+T A+ ++ P
Sbjct: 2260 RTPAAAAAMNLASPRTAVAP 2279
Score = 47.8 bits (112), Expect = 1e-04
Identities = 303/1420 (21%), Positives = 460/1420 (32%), Gaps = 252/1420 (17%)
Query: 238 SPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLE 297
S S S +LS ++ S+ S SS +L+ P RERS S + + GL
Sbjct: 1375 STRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAV-PRTPSRERSSSASSPEMKDGLPR 1433
Query: 298 GMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVP 357
+ G + + ++ S+ G + +G + + P K +P
Sbjct: 1434 TPSRRSRSGSSPGLRDGSGTPSRHSLSGSS---PGMKDIPRTPSRGRSECDSSPEPKALP 1490
Query: 358 P-PSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFR----HRERPSSWSSLDQKRL 412
P + PSS E L P+ + D R R R S LD K
Sbjct: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPS 1550
Query: 413 CRPQANSLGSLKSPFIEEQLHTVLEK------SPE---------------NSPPVKPKHN 451
PQ S S SP + + T L + SPE +SP VK K
Sbjct: 1551 ASPQERS-ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
Query: 452 YTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGMLYPALAKESGYIAPQGACNKM 511
+AQ G P P P P ++ S SS+ P +P+G+ +
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSR----SGSSSKGRGP---------SPEGSSSTE 1656
Query: 512 ATIDENGNQNGSGRPGFAFCQPLEHDLLSPVEKKPEATAKYVPSKVHFCSVPENEEDASL 571
++ E+ ++ + R G S +P+ ++ P + S PE A L
Sbjct: 1657 SS-PEHPPKSRTARRG------------SRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 572 KRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQ 631
R S ++ T S P H S P + + E RSSR
Sbjct: 1704 SR-------RSRSASSSPETRSRTPPRHRRS---PSVSSPEPAEKSRSSR---------- 1743
Query: 632 EDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGG 691
+ +SA SS + S R S RG Q
Sbjct: 1744 -------------------------RRRSA-SSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
Query: 692 RPTCAVNTKAEDPGRKAAPDLGSHLDRQVSYPRPEGRTGASASFNSTDPSPEEPPAPSHP 751
R T+ D ++ R S R R + ++S P+ +E
Sbjct: 1778 RREKTRTTRRRDRS-GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQE-----SS 1831
Query: 752 HTSSLGRRGPG---PGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHN 808
TSS RRG P S + P + S R S+ P + +
Sbjct: 1832 RTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI-------S 1884
Query: 809 YRPHRTVSTSSTSGNDFEETKAHIRFSES-AEPLGNGEQHFKNGEL-KLEEASRQPCGQQ 866
R R+ ++ + T R S S A P+ + + + SR P ++
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 867 LSGGASDSGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSPESPLLDAPFSRAYRN 926
S S P R+ + S P R R S SP+ SR+ +
Sbjct: 1945 ----RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRR-SRSRTS 1999
Query: 927 SIKDAQSRVLGATSFRRRDLELGAPV---ASRSWRPRPSSAHVGLRSPEA----SASASP 979
+ +SR + RRR P SRS P RSP A S S +P
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059
Query: 980 HTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKR---SYSEPEKMNEVGIV---- 1032
T R + S+T + + R + R TP + S + P +N +
Sbjct: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
Query: 1033 EEAEPAPLGPQRN-GMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALAD--- 1088
P PL R+ GM P S + ++ G S + GP + Q++++ +
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGG--SMMDGPGPRIPDHQRTSVPENHA 2177
Query: 1089 ---------YIQRKTGKRPTSAAGCSL-----QEPGPLRERAQSAYLQPGPAALEGSGL- 1133
I T + P S + L Q P P+ + L+ PAA S +
Sbjct: 2178 QSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMS----LRTAPAANLASRIP 2233
Query: 1134 ---ASASSLSSLREPSL-------QPRREATLLPATVAETQQAPRDRSSSFAGGRR---- 1179
A+A +L+S R P++ R A +A + A + + A R
Sbjct: 2234 AASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAP 2293
Query: 1180 ----LGERRRGDL--LSGANGGTRGT----QRGDETPREPSSWGARAGKSMSAEDLLERS 1229
G R L LS GT T TP+ P+ SA + RS
Sbjct: 2294 AVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPA----------SANLVGPRS 2343
Query: 1230 DVLAGPVHVR-SRSSPA------TADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSE 1282
PV++ SR++ A T+ + L G + V Y G S +
Sbjct: 2344 AHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLD 2403
Query: 1283 RGQEE---MLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQ------ASRTPC-- 1331
R + P +T S +G + S P D R + ++ C
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 1332 -PRPPLAGTQGLVTDTRAAPLTPIG-------TPLPSAIPSGYCSQDGQTGRQ---PLPP 1380
P+AG+Q L + A + G P P S TG Q L
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 1381 YTPAMMHR-------SNGHTLTQPPGPRGCEGDGPEHGVEEGT----RKRVSLPQWPPPS 1429
PA R S+ + + G EG+ + V+L + P P+
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 1430 RAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRI 1489
A A RE PE + P + S S S+S + + S+ S
Sbjct: 2584 PAP-KEAVREGRPPEPT--PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 1490 SESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPP 1529
S S SP P + P P+A P PPP
Sbjct: 2641 SSSSSSSSPSPAK----------PGPQALPKPASPKKPPP 2670
Score = 35.0 bits (79), Expect = 0.74
Identities = 90/429 (20%), Positives = 139/429 (32%), Gaps = 49/429 (11%)
Query: 961 PSSAHVGLRSPEASASASPHTPRERHSVTP---AEGDLARPVPPAARRGARRRLTPEQKK 1017
PSS+ R+P+A ASA+ PR H+ P A A + PA+ A R+ P
Sbjct: 2324 PSSS----RTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA--RMAPALSG 2377
Query: 1018 RSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPE 1077
+ + P +P R R P S+ + R ER A S S G
Sbjct: 2378 ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER---APSPSSRMGQA 2434
Query: 1078 LKQFQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASAS 1137
Q D + + + C + + P+ A S L G A S +
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV---AGSQSLSSGAVATTTSSAGDHN 2491
Query: 1138 SLSSLREPSL-------QPRREATLLPATVAETQQAP--RDRSSSFAGGRRLGERRRGDL 1188
+ S+ P + P P+ +A Q A R SSS +
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551
Query: 1189 LSGANGGTRGTQRGDETPREPSSWGARAGKSMSA--EDLLERSDVLAGPVHVRSRSSPAT 1246
S ++G + G P +P R A E + E P + RSS ++
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611
Query: 1247 ADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKA 1306
+ S + S S S S +P G +A
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-------------SPSPAKPGPQA 2658
Query: 1307 IGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGY 1366
+ + P + P R+ PR P+ + D+R+ +P+ PS PS
Sbjct: 2659 LPKPASPKKPP------PGERRSRSPRKPIDS----LRDSRSLSYSPVERRRPSPQPSPR 2708
Query: 1367 CSQDGQTGR 1375
Q + R
Sbjct: 2709 DQQSSSSER 2717
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 60.1 bits (144), Expect = 2e-08
Identities = 171/703 (24%), Positives = 244/703 (34%), Gaps = 135/703 (19%)
Query: 955 RSWRPRPSSAHVGLRSPEASASASPHTPRE----RHSVTPAEGDLARP---VPPAARRGA 1007
+S R P ++ S S A T + R + +G RP P + + G
Sbjct: 154 QSSRTGPDEDNISFCSQTTSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGR 213
Query: 1008 RRRLTPEQKKRSYSEPEKMN-EVGIVEEAEPAPLGPQ----RNGMRFPESSVADRRRLFE 1062
RRR E++ P+ + E+G+ E E AP P+ R+ +R P +V R R
Sbjct: 214 RRR---ERRSTVLGLPQHVQKELGLRNERE-APGTPRAPGARDAVRIP--TVDGRPRGTS 267
Query: 1063 RDGKACSTLSL-----SGPELKQFQQSALA------DYIQRKTGKR-PTSAAGCSLQEPG 1110
G S +L +G E + Q + ++ R TG R P SL PG
Sbjct: 268 GMGARVSLQALEAEAEAGAETEAMLQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPG 327
Query: 1111 PLRERAQSAYLQPGPAALEGSGLASASSLSSLREPS-LQPRREATLLPATVAETQQAPRD 1169
+ L P + A+ LS L + L P + L T
Sbjct: 328 LTGGAGPAEPLSPAMSISP-----QATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSL 382
Query: 1170 RSSSFAGGRRLGE-------RRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSA 1222
S+S A R LG + R S ++ +Q D + S+ ++ G
Sbjct: 383 HSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQP 442
Query: 1223 EDLLERSDVLAGPVHVRSRSSPA---TADKRQDVLL---GQDSGFGL----VKDPCYLAG 1272
E + V+ P R SP+ TA+ + + GQ SG + +K P
Sbjct: 443 ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP---PP 499
Query: 1273 PGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPG--TLDHQRQASRTP 1330
P R+ S +RG L G G + + P T A P
Sbjct: 500 PPRRTHSLHQRG----------LAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAP 549
Query: 1331 CP-RPPLAGTQGLVTD-TRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPL----PPYTPA 1384
CP P + GL +R P +P T PS SGY SQ G P PP +P
Sbjct: 550 CPPNPANSWVPGLSPGGSRRPPRSPERTLSPS---SGYSSQSGTPTLPPKGLAGPPASPG 606
Query: 1385 MMHRSNGHTLT--QPPG----------------PRGCEGDGPEHGVEEGTR------KRV 1420
+T + PG P + GP+ G R +V
Sbjct: 607 KAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKV 666
Query: 1421 SLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPS 1480
P PPPS+ + + A AP A +P ST+D +P
Sbjct: 667 PAPFSPPPSKPRSPNPA----------APALA------APAVVPGPVSTTDASPQ--SPP 708
Query: 1481 TPGRISLRISES--VLRDS-----------PPPHEDYEDEVFVRDPHPKATSSPTFEPLP 1527
TP + ES + +D PPP + EV V P T+ +
Sbjct: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768
Query: 1528 PPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPS 1570
PPPPPP+ E SM DFPPP A S +P GP S
Sbjct: 769 WPPPPPPAPEEQDLSMADFPPPEEAFFSVA---SPEPAGPSGS 808
Score = 40.0 bits (92), Expect = 0.023
Identities = 231/1118 (20%), Positives = 337/1118 (30%), Gaps = 272/1118 (24%)
Query: 740 PSPEEPPAPSHPHTSSLGRRGP-----------GPGSASALQGFQYGKPHCSVLEKVSKF 788
P+ EEP P P R G G G + +P +K
Sbjct: 10 PAAEEPGNPGGPPRRKKSRSGASGLRRAFSWLRGKRRKKKAAGAEGAEPAAPRAKKAEDK 69
Query: 789 EQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEP-LGNGEQH 847
+R +G R GS N + H +V G+ +E + ++ F P L
Sbjct: 70 AKRAKGKGR----GSAKAENDK-HLSVGPGQGPGSAVDEHQDNVFFPSGRPPHLEELHTQ 124
Query: 848 FKNGELKLEEASRQPCGQQLSGGASDSG---------RGPQRPDARLLRSQSTFQLSSEP 898
+ G L+ +Q +L+ G D G GP + +++ S
Sbjct: 125 AQEGLRSLQHQEKQ----KLNKGGWDHGDTQSIQSSRTGPDEDNISFCSQTTSYVAESST 180
Query: 899 EREP-----EWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLEL----- 948
+ E R GS P P S ++ +S VLG +++L L
Sbjct: 181 AEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNERE 240
Query: 949 --GAP----------VASRSWRPRPSS---AHVGLRSPEASASASPHTPR--ERHSVTPA 991
G P + + RPR +S A V L++ EA A A T +RH
Sbjct: 241 APGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAMLQRHIDRVY 300
Query: 992 EGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPA-PLGPQR------ 1044
D R R P + S + P G E PA + PQ
Sbjct: 301 RDDTF------VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKL 354
Query: 1045 --NGMRFPESSVADRRRLFERDGKACST--------------LSLSGPELKQFQQSALAD 1088
+ + P V R R CS S+S P+ + S+ +D
Sbjct: 355 IPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSD 414
Query: 1089 YIQRKTGKRPTSAAGCSLQEPG-----PLRERAQSAYLQP-----GPAALEGSGLASAS- 1137
+ G +L G P A ++ + P G + G A AS
Sbjct: 415 TWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASD 474
Query: 1138 ---------------SLSSLREPSLQPRREATL-------------LPATVAETQQA--- 1166
SL L+ P PRR +L LP QQ
Sbjct: 475 TLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLP 534
Query: 1167 --PRDRSSSFAGGRRLGERRRGDLLSGAN-GGTRGTQRGDETPREPSSWGARAGKSMSAE 1223
P S AG + G + GG+R R E PSS G S +
Sbjct: 535 RPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSS-----GYSSQSG 589
Query: 1224 DLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSER 1283
LAGP ++ P K + V + G + L S
Sbjct: 590 TPTLPPKGLAGPPASPGKAQPP---KPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS 646
Query: 1284 GQEEMLPLFHHLTPRWGGSGCKAIGDSSV---PSECPGTLDHQRQASRTPCPRPPL---- 1336
G + + PL GD V + P R+P P P
Sbjct: 647 GPQILTPL----------------GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAP 690
Query: 1337 AGTQGLVTDTRAAPLTPIGTPLPSAIP---SGYCSQDGQTGRQPLPPYTPAMMHRSNGHT 1393
A G V+ T A+P +P TP + P S S+D P P Y P
Sbjct: 691 AVVPGPVSTTDASPQSP-PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV 749
Query: 1394 LTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFAN 1453
+ + P E + + P WPPP AP+ +
Sbjct: 750 VVEAPS------------ASETAEEPLQDPNWPPPP----------------PPAPEEQD 781
Query: 1454 LKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDP 1513
L + S + P+ P G +P +S + S
Sbjct: 782 LSMADFPPPEEAFFSVASPE-PAGPSGSPELVSSPAASS--------------------- 819
Query: 1514 HPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEG------- 1566
AT+ P P PPP P P S P H A+L ++P G
Sbjct: 820 -SSATALQIQPPGSPDPPPAPPAPAPASS------APGHV---AKLPQKEPVGCSKGGGP 869
Query: 1567 PRPSFN------KLSKVTIARERHMPGAA--HVVGSQTLASRLQTSIKGSEAESTPPSFM 1618
PR L ++ R PG A +G L+ ++ G A P
Sbjct: 870 PREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSG-RASPVPAPSS 928
Query: 1619 SVHA-------QLAGSLG---GQP------------APIQTQSLSHDPVSGTQGLEKKVS 1656
+HA LA S G QP +P T S S LE+ VS
Sbjct: 929 GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVS 988
Query: 1657 PDPQKSSEDIRTEALAKEIVHQDKSLADILDPDSRLKT 1694
P+ Q L + +V + +S+++ P + K+
Sbjct: 989 PETQAD--------LQRNLVAELRSISEQRPPQAPKKS 1018
Score = 32.7 bits (73), Expect = 3.7
Identities = 69/288 (23%), Positives = 105/288 (36%), Gaps = 31/288 (10%)
Query: 871 ASDSGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKD 930
A SG P+ + S S L +P P D P +P +P AP S A + K
Sbjct: 803 AGPSG-SPELVSSPAASSSSATALQIQPPGSP---DPPPAPPAP---APASSAPGHVAKL 855
Query: 931 AQSRVLGATSFRRRDLE-LGAPVASRSW----RPRPSSAHVGLRSPEASASASPHTPRER 985
Q +G + E +GAP+ + S R R A G +P SA P P R
Sbjct: 856 PQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA-PQKPLRR 914
Query: 986 HSVTPAEGDLARPVP-PAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQR 1044
A A PVP P++ A RL K S + E ++ P GP
Sbjct: 915 -----ALSGRASPVPAPSSGLHAAVRL----KACSLAASEGLSSA--------QPNGPPE 957
Query: 1045 NGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGC 1104
R P+S + +F + + PE + Q L ++ + +RP A
Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017
Query: 1105 SLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRRE 1152
S + P P+ + P + + +A + L + +RE
Sbjct: 1018 SPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRE 1065
>gi|61743948 abl-interactor 1 isoform d [Homo sapiens]
Length = 476
Score = 58.2 bits (139), Expect = 8e-08
Identities = 66/266 (24%), Positives = 97/266 (36%), Gaps = 40/266 (15%)
Query: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377
GTL ++ P P PP++G L +T L P+ P +P+ Y + + G Q
Sbjct: 164 GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 219
Query: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE-GTRKRVSLPQWP------PPSR 1430
P T ++ R H+ G G G G G V P P P S
Sbjct: 220 SPGRTASLNQRPRTHS-----GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA 274
Query: 1431 AKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRIS 1490
+ + +S + Y++ S+ + S + P G + IS+
Sbjct: 275 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIA-- 331
Query: 1491 ESVLRDSPPPHEDYEDEV----FVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDF 1546
PPP ++ FV SPT PPPPPP + P++ DD
Sbjct: 332 -----PPPPPMPQLTPQIPLTGFVARVQENIADSPT------PPPPPPPDDIPMF--DDS 378
Query: 1547 PPPPPHTVCEAQLDSEDPEGPRPSFN 1572
PPPPP +D ED E +N
Sbjct: 379 PPPPP----PPPVDYEDEEAAVVQYN 400
>gi|61743944 abl-interactor 1 isoform b [Homo sapiens]
Length = 481
Score = 58.2 bits (139), Expect = 8e-08
Identities = 66/266 (24%), Positives = 97/266 (36%), Gaps = 40/266 (15%)
Query: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377
GTL ++ P P PP++G L +T L P+ P +P+ Y + + G Q
Sbjct: 169 GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 224
Query: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE-GTRKRVSLPQWP------PPSR 1430
P T ++ R H+ G G G G G V P P P S
Sbjct: 225 SPGRTASLNQRPRTHS-----GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSA 279
Query: 1431 AKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRIS 1490
+ + +S + Y++ S+ + S + P G + IS+
Sbjct: 280 PGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFS-AQPHVNGGPLYSQNSISIA-- 336
Query: 1491 ESVLRDSPPPHEDYEDEV----FVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDF 1546
PPP ++ FV SPT PPPPPP + P++ DD
Sbjct: 337 -----PPPPPMPQLTPQIPLTGFVARVQENIADSPT------PPPPPPPDDIPMF--DDS 383
Query: 1547 PPPPPHTVCEAQLDSEDPEGPRPSFN 1572
PPPPP +D ED E +N
Sbjct: 384 PPPPP----PPPVDYEDEEAAVVQYN 405
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 57.0 bits (136), Expect = 2e-07
Identities = 86/408 (21%), Positives = 131/408 (32%), Gaps = 79/408 (19%)
Query: 1313 PSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPS-------- 1364
P + P +Q + P P PP + Q +++P I T +P P
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP 819
Query: 1365 -GYCSQDGQTGRQP-LPPYTPAMMHRS-----NGHTLTQPPGPRGCEGDGPEHGVEEGTR 1417
G+ +Q QP LPP+ P S N H + PP P
Sbjct: 820 IGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAA 879
Query: 1418 -------------KRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFAN------LKHYQ 1458
P P P A+ ED EE AP + L+ Q
Sbjct: 880 LPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED---EEPPAPPLTSMQMQLYLQQLQ 936
Query: 1459 KQQS----LPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPH 1514
K Q LPS+ S P PL P P + + + + PPP P
Sbjct: 937 KVQPPTPLLPSVKVQSQPPPPLPPPPHPS-----VQQQLQQQPPPP------------PP 979
Query: 1515 PKATSSPTFEPLPPP---------------PPPPPSQETPVYSMDDFPPPPPHTVCEAQL 1559
P+ P + PPP PPPP + P + PPPP Q+
Sbjct: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV 1039
Query: 1560 DSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMS 1619
P +K + R P ++ S ++ + + ++ P
Sbjct: 1040 IQHHHS---PRHHKSDPYSTGHLREAPSPL-MIHSPQMSQFQSLTHQSPPQQNVQPKKQE 1095
Query: 1620 VHAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIR 1667
+ A A + QP + + H P+ ++ + P+P K E I+
Sbjct: 1096 LRA--ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK 1141
Score = 39.3 bits (90), Expect = 0.039
Identities = 75/355 (21%), Positives = 105/355 (29%), Gaps = 64/355 (18%)
Query: 1322 HQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPY 1381
H +Q + P P P P P P P P Q +QP PP
Sbjct: 742 HHQQMQQAPAPVPQ-------------QPPPPPQQPPPPPPP--------QQQQQPPPPP 780
Query: 1382 TPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED- 1440
P M + + P P T+ V PQ P H +
Sbjct: 781 PPPSMPQQAAPAMKSSPPPF------------IATQVPVLEPQLPGSVFDPIGHFTQPIL 828
Query: 1441 SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPP 1500
LP+ P + L S P P P R S R + + + PP
Sbjct: 829 HLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPP 888
Query: 1501 HEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLD 1560
SP P P PP +Q V D+ PP PP T + QL
Sbjct: 889 -----------------AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
Query: 1561 SEDPEGPRPSFNKLSKVTIARE--RHMPGAAHVVGSQTLASR------LQTSIKGSEAES 1612
+ + +P L V + + +P H Q L + Q +
Sbjct: 932 LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ 991
Query: 1613 TPPSFMSVHAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIR 1667
PP + + + QP P Q Q H P ++ P P K + I+
Sbjct: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG-----QQPPPPQPAKPQQVIQ 1041
Score = 35.0 bits (79), Expect = 0.74
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 2/53 (3%)
Query: 1501 HEDYEDEVFVRDPHPKATSSPTFEPLPPPPPP--PPSQETPVYSMDDFPPPPP 1551
H E + H + +P P PPPPP PP P PPPPP
Sbjct: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP 782
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 57.0 bits (136), Expect = 2e-07
Identities = 143/638 (22%), Positives = 209/638 (32%), Gaps = 87/638 (13%)
Query: 973 ASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIV 1032
A A+++P + A G + P+ PA R TP Q K + P K+ ++
Sbjct: 310 AGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQL--- 366
Query: 1033 EEAEPAPLGP-------QRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSA 1085
P P P Q P+ A + F GKA + LSG Q +
Sbjct: 367 ---TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV 423
Query: 1086 LADYIQRKTGKRPTSAAGCSLQEPGPLRERAQ-SAYLQPGPAALEGSGLASASSLSSLRE 1144
TG P G +L +P + Q S+ + P L G
Sbjct: 424 FKQPPATTTGAAPPQPPG-ALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA----- 477
Query: 1145 PSLQPRREATLLPATVAE---TQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQR 1201
P++Q ++ + LPA V AP A + G L G
Sbjct: 478 PAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG---------- 527
Query: 1202 GDETPREPSSWGARAGKSMSAEDLLERSDVL--------AGPVHVRSRSSPATADKRQDV 1253
P GA + +SA + L AG + +S+ +PA V
Sbjct: 528 ----PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPA-GPAATTV 582
Query: 1254 LLG---QDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIG-- 1308
L G S ++ P L P + + + E + P S +G
Sbjct: 583 LQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPP--AVSTPLPLGLQ 640
Query: 1309 --DSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGY 1366
+ P + P + TP P P LA + + +G P PSA P+
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIV---------LGQP-PSATPTAI 690
Query: 1367 CSQDG-------QTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKR 1419
+QD + +QPL P + ++ PP + P V +G
Sbjct: 691 LTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPA----QDPAPATPVAKGAGLG 746
Query: 1420 VSLPQ-WPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGA 1478
P P+ A AA P SS+P + LPS T P P
Sbjct: 747 PQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRP--- 803
Query: 1479 PSTPGRISLRISESVLRDSPPPHEDYE-DEVFVRD-----PHPKATSSPTFEPLPPPPPP 1532
PS P +S SE L PPP +FV P P + +PT P PP PP
Sbjct: 804 PSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT-APGPPQPPL 862
Query: 1533 PPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPS 1570
P + P + P PP + A S + P+
Sbjct: 863 RPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPA 900
Score = 40.0 bits (92), Expect = 0.023
Identities = 60/246 (24%), Positives = 89/246 (36%), Gaps = 42/246 (17%)
Query: 1327 SRTPCPRPPLAGTQGL---VTDTRAAPL--------TPIGTPLPSAIPS-GYCSQDGQTG 1374
++ P P P+A GL D++A+P P+ P PS+ PS + + G +
Sbjct: 730 AQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSP 789
Query: 1375 RQPLP-PYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQW--PPPSR- 1430
P P P P S ++++PP P V Q PPP+
Sbjct: 790 HLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASN 849
Query: 1431 -AKWAHAAREDSLPEESSAPD--FANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISL 1487
A A + L +S P+ H + ++ S+S+ + L AP TP L
Sbjct: 850 PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQL 908
Query: 1488 RISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTF----EPLPPPPPPPPSQETPVYSM 1543
+ PP + PH T PT EP PPPPPP + +
Sbjct: 909 QF---------PPSQG---------PHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 1544 DDFPPP 1549
P P
Sbjct: 951 PALPQP 956
Score = 33.9 bits (76), Expect = 1.6
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 15/120 (12%)
Query: 1433 WAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRIS-- 1490
WA A+ SL SS+ A+ + +PS + P P+ RI L++
Sbjct: 1261 WARAS--SSLSSSSSSSSAASSLDADEDGPMPS---RNRP--PIKTYEARSRIGLKLKIK 1313
Query: 1491 -ESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPP 1549
E+ L S H D V P P P PPPPPPP Q + D PPP
Sbjct: 1314 QEAGL--SKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQ---MNGTVDHPPP 1368
Score = 33.5 bits (75), Expect = 2.1
Identities = 16/42 (38%), Positives = 19/42 (45%)
Query: 1510 VRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPP 1551
V P P + EP P PPPPPP ++D PP P
Sbjct: 1330 VHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP 1371
Score = 33.1 bits (74), Expect = 2.8
Identities = 28/120 (23%), Positives = 40/120 (33%), Gaps = 22/120 (18%)
Query: 1516 KATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLS 1575
K + +P+ PPPPP + + PPPPP +D P P
Sbjct: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP-------- 1371
Query: 1576 KVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQLAGSLGGQPAPI 1635
ER G A L + ++ G A P+ + GG PAP+
Sbjct: 1372 ------ERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPA--------GRARGGSPAPL 1417
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 55.5 bits (132), Expect = 5e-07
Identities = 131/595 (22%), Positives = 193/595 (32%), Gaps = 77/595 (12%)
Query: 1093 KTGKRPTSAAG-----CSLQEPGPLRERAQ-SAYLQPGPAALEGSGLASASSLSSLREPS 1146
+T + P S G PGP+ + S +PGP +G +++ +++
Sbjct: 81 RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA------ 134
Query: 1147 LQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDET- 1205
R +AT P A + A RD S G RR S A G G R +
Sbjct: 135 ---RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR----SRAAGTEVGLPRPAPSA 187
Query: 1206 -PREPSSWGARAGKSMSAEDLLERSDVL-------AGPVHVRSRSSPATADKRQDVLLGQ 1257
PR P+ ++ S S E S G SRS ++A
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247
Query: 1258 DSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECP 1317
S G + P + + P + L Q + P P G + S +
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAA--------PLTPIGTPLPSAIPS----- 1364
+ Q +P PP T L + T A PL+P+ TP P A P+
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 1365 --GYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSL 1422
S PL +P + H L P P P V+ S
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP------PSPPVQAPFSPPASP 419
Query: 1423 PQWP---PPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAP 1479
P P PPS+A + AA +P A + Q+ P L + PL
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-----PLQLA 474
Query: 1480 STPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP 1539
P + ++ L+ P P + + P + S P PPP PP P
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQA----PFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 1540 VYSMDDFPPPPPHTVCEAQLDSEDPE----GPRPSFNKLSKVTIARERHMPGAAHVVGSQ 1595
+ + PP P + + P+ GPR +T+A P S
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR--------LTLALAPGPPPPPSRSPSS 582
Query: 1596 TLASRLQTSIKGSEAESTPPSFMSVHAQLAGSLGGQPAPIQTQSLSHDPVSGTQG 1650
TL S + S A STP + G P P + H P + ++G
Sbjct: 583 TL-SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH-PAAWSRG 635
Score = 38.9 bits (89), Expect = 0.051
Identities = 160/709 (22%), Positives = 215/709 (30%), Gaps = 120/709 (16%)
Query: 874 SGRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQS 933
SGRG + P A+ + S +SS R P + + A + A + + +
Sbjct: 88 SGRGERAPPAK---NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144
Query: 934 RVLGATSFRRRDLE---LGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTP 990
L A + RRD G P + + R R + VGL P SA P T R SV+
Sbjct: 145 SALSAGA--RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 991 A-EGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGM-R 1048
A E P P A RR + RS S + PA GP G R
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS-------SATPLSSPARSGPSARGTPR 255
Query: 1049 FPESSVADRRRLFE--RDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSL 1106
P + + + R + + P L S LA P+ +A SL
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSAPPSPSAPPSL 312
Query: 1107 QE-PGPLRERAQSAYLQPGPAALEGS-GLASASSLSSLREPSLQPRREATLLPATVAETQ 1164
Q P P A G L+ + + LS L P Q L P +
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372
Query: 1165 QAPRDRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAED 1224
A S + LL + + P S A S SA
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAP-----FSPPPSPPVQAPFSPPASPPVSPSATP 427
Query: 1225 LLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSERG 1284
+ LA P S PA+ + L P LA P ++
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 1285 QEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVT 1344
+ LP S P+ PG AS P PLA
Sbjct: 488 PLQALP--------------------SPPASFPGQAPFSPSAS---LPMSPLATPPPQAP 524
Query: 1345 DTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCE 1404
AAPL + P PP +P + +PP P
Sbjct: 525 PVLAAPLLQV---------------------PPSPPASPTL------QAPRRPPTP---- 553
Query: 1405 GDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLP 1464
GP+ V G R ++L PPP ++ S S PD A
Sbjct: 554 --GPDTSV-SGPRLTLALAPGPPPPPSR--------SPSSTLSGPDLAG----------H 592
Query: 1465 SLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDY---EDEVFVRDPHPK-ATSS 1520
S +TS P+ G S P E SPPP + + R P P A
Sbjct: 593 SSSATSTPEELRGYDSGP--------EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 644
Query: 1521 PTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRP 1569
PLP PP P + ++ + P T LD GP P
Sbjct: 645 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD----PGPSP 689
>gi|61743942 abl-interactor 1 isoform a [Homo sapiens]
Length = 508
Score = 55.1 bits (131), Expect = 7e-07
Identities = 75/286 (26%), Positives = 103/286 (36%), Gaps = 53/286 (18%)
Query: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377
GTL ++ P P PP++G L +T L P+ P +P+ Y + + G Q
Sbjct: 169 GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 224
Query: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEE-GTRKRVSLP----------QWP 1426
P T ++ R H+ G G G G G V P P
Sbjct: 225 SPGRTASLNQRPRTHS-----GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPENISVP 279
Query: 1427 PPSRAKWAHAAREDSLPEES--SAPDFANLKHYQKQQSLPSLCSTSDPDTPLG----APS 1480
PPS A A LP + +AP A Y S +++ T G PS
Sbjct: 280 PPSGAPPA-PPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPS 338
Query: 1481 TPGRIS---------LRISESV-LRDSPPPHEDYEDEV----FVRDPHPKATSSPTFEPL 1526
+ S L S+ + PPP ++ FV SPT
Sbjct: 339 VTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIADSPT---- 394
Query: 1527 PPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFN 1572
PPPPPP + P++ DD PPPPP +D ED E +N
Sbjct: 395 --PPPPPPPDDIPMF--DDSPPPPP----PPPVDYEDEEAAVVQYN 432
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 54.7 bits (130), Expect = 9e-07
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 34 GGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKEAV 92
G APWGF + GG + P++++KV E GKA + L+ GD +V IN E EA
Sbjct: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKAK--DADLRPGDIIVAINGESAEGMLHAEAQ 66
Query: 93 SLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
S ++ S LRL + R T PG + +S
Sbjct: 67 SKIRQSPSPLRLQLDRSQATSPGQTNGDSS 96
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 54.7 bits (130), Expect = 9e-07
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 34 GGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKEAV 92
G APWGF + GG + P++++KV E GKA + L+ GD +V IN E EA
Sbjct: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKAK--DADLRPGDIIVAINGESAEGMLHAEAQ 66
Query: 93 SLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
S ++ S LRL + R T PG + +S
Sbjct: 67 SKIRQSPSPLRLQLDRSQATSPGQTNGDSS 96
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 54.7 bits (130), Expect = 9e-07
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 34 GGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKEAV 92
G APWGF + GG + P++++KV E GKA + L+ GD +V IN E EA
Sbjct: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKAK--DADLRPGDIIVAINGESAEGMLHAEAQ 66
Query: 93 SLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
S ++ S LRL + R T PG + +S
Sbjct: 67 SKIRQSPSPLRLQLDRSQATSPGQTNGDSS 96
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 53.9 bits (128), Expect = 2e-06
Identities = 89/396 (22%), Positives = 127/396 (32%), Gaps = 58/396 (14%)
Query: 1297 PRWGGSGCKAIGDSSVPSECPGTLD---HQRQASRTPCPRPPLAGTQGLVTDTRAAP--- 1350
P+ GG+ G + P T AS P +PP G + P
Sbjct: 235 PKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANF 294
Query: 1351 --LTPIGTPLPSAIPSGYCSQDGQ-TGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDG 1407
+TP P P+ P S G QPLP + P+ G PPGP G
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG-GLPPGPE----KG 349
Query: 1408 PEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLC 1467
P + S PP R ++ ++ + SS+ ++ + Q+LPS
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYP 409
Query: 1468 STSDPDTPLGAPSTPGRISLRI--SESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEP 1525
+ P T L + P + + S++V PPP Y + + HP T
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469
Query: 1526 LPPPPP------------------PPPSQETPVYSMDDFPPPP---PHTVCEAQLDSEDP 1564
PP Q+ + + PPPP PH + P
Sbjct: 470 STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP 529
Query: 1565 EGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQL 1624
PS L + PG AH+ + S Q G PP S ++
Sbjct: 530 YAMSPSLGSL-------RPYPPGPAHLPPPHSQVSYSQAGPNG------PPVSSSSNSSS 576
Query: 1625 AGSLGGQPAPIQTQSLSH-DPVSGTQGLEKKVSPDP 1659
+ S G P SH P G QG P P
Sbjct: 577 STSQGSYPC-------SHPSPSQGPQGAPYPFPPVP 605
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 53.9 bits (128), Expect = 2e-06
Identities = 89/396 (22%), Positives = 127/396 (32%), Gaps = 58/396 (14%)
Query: 1297 PRWGGSGCKAIGDSSVPSECPGTLD---HQRQASRTPCPRPPLAGTQGLVTDTRAAP--- 1350
P+ GG+ G + P T AS P +PP G + P
Sbjct: 235 PKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANF 294
Query: 1351 --LTPIGTPLPSAIPSGYCSQDGQ-TGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDG 1407
+TP P P+ P S G QPLP + P+ G PPGP G
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG-GLPPGPE----KG 349
Query: 1408 PEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLC 1467
P + S PP R ++ ++ + SS+ ++ + Q+LPS
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYP 409
Query: 1468 STSDPDTPLGAPSTPGRISLRI--SESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEP 1525
+ P T L + P + + S++V PPP Y + + HP T
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469
Query: 1526 LPPPPP------------------PPPSQETPVYSMDDFPPPP---PHTVCEAQLDSEDP 1564
PP Q+ + + PPPP PH + P
Sbjct: 470 STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP 529
Query: 1565 EGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQL 1624
PS L + PG AH+ + S Q G PP S ++
Sbjct: 530 YAMSPSLGSL-------RPYPPGPAHLPPPHSQVSYSQAGPNG------PPVSSSSNSSS 576
Query: 1625 AGSLGGQPAPIQTQSLSH-DPVSGTQGLEKKVSPDP 1659
+ S G P SH P G QG P P
Sbjct: 577 STSQGSYPC-------SHPSPSQGPQGAPYPFPPVP 605
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKE 90
+ GGAPWGF L+GG E +PL ++K+ KA S L GDEVV IN + E
Sbjct: 11 MTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS--GSGLCEGDEVVSINGNPCADLTYPE 68
Query: 91 AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSG 133
+ L++ +L+++++R + A + + EHLT G
Sbjct: 69 VIKLMESITDSLQMLIKRP-SSGISEALISENENKNLEHLTHG 110
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKE 90
+ GGAPWGF L+GG E +PL ++K+ KA S L GDEVV IN + E
Sbjct: 11 MTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS--GSGLCEGDEVVSINGNPCADLTYPE 68
Query: 91 AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSG 133
+ L++ +L+++++R + A + + EHLT G
Sbjct: 69 VIKLMESITDSLQMLIKRP-SSGISEALISENENKNLEHLTHG 110
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKE 90
+ GGAPWGF L+GG E +PL ++K+ KA S L GDEVV IN + E
Sbjct: 11 MTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKAS--GSGLCEGDEVVSINGNPCADLTYPE 68
Query: 91 AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSG 133
+ L++ +L+++++R + A + + EHLT G
Sbjct: 69 VIKLMESITDSLQMLIKRP-SSGISEALISENENKNLEHLTHG 110
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 8/132 (6%)
Query: 4 TTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKA 63
TT+ + + AT+ + Y G +GF+L+GG E+ L + ++ E G A
Sbjct: 1128 TTKPKQESQFEFKAPQATQEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPA 1187
Query: 64 DTLSSKLQAGDEVVHIN-EVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
+ K++ GDE++ IN E T + A+ L+K + +RL ++R D + G S
Sbjct: 1188 ER-CGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRG---DGSVPEYGGS 1243
Query: 123 NFVSPEHLTSGP 134
N+ E++ S P
Sbjct: 1244 NY---ENIPSFP 1252
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 16/135 (11%)
Query: 38 WGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEV-TLSSSRKEAVSLVK 96
+GF + GG E GEP+ I + G ADT +L++GDE++ ++ + S + V L++
Sbjct: 851 FGFRILGGNEPGEPIYIGHIVPLGAADT-DGRLRSGDELICVDGTPVIGKSHQLVVQLMQ 909
Query: 97 GSYKT--LRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRS 154
+ K + L VRR V F P+ P + S L +
Sbjct: 910 QAAKQGHVNLTVRRKVV------------FAVPKTENEVPSPASSHHSSNQPASLTEEKR 957
Query: 155 EPAGRPHSWHTTKSG 169
P G +S +T SG
Sbjct: 958 TPQGSQNSLNTVSSG 972
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/226 (27%), Positives = 85/226 (37%), Gaps = 34/226 (15%)
Query: 1333 RPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPS-GYCSQDGQTGRQPLPPYTPAMMHRSNG 1391
RPPL G T A P +P P +PS G+ S + R +PP P + + +
Sbjct: 125 RPPLLPPGG--RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 1392 HTLTQPPGPRGCEGDGPEHG---VEEGTRKRVSLPQWPPPSRAKWAHAAREDSL---PEE 1445
P PR + G V G R+ P PPP A S+ P
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT-PPPFPGNRGTALGGGSIRQSPLS 241
Query: 1446 SSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYE 1505
SS+P + + LP S + D P P G S+ R++ PP
Sbjct: 242 SSSP-------FSNRPPLPPTPSRALDDKPPPPPPPVGN-----RPSIHREAVPPPPPQN 289
Query: 1506 DEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPP 1551
++ P +T P+ PPPPPPPS+ P PP PP
Sbjct: 290 NK-----PPVPSTPRPSASSQAPPPPPPPSRPGP-------PPLPP 323
Score = 44.3 bits (103), Expect = 0.001
Identities = 50/196 (25%), Positives = 65/196 (33%), Gaps = 24/196 (12%)
Query: 1379 PPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEH--GVEEGTRKRVSLPQWPPPSRAKWAHA 1436
PP P ++ + P GP P H G E R R+ PPP
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM-----PPPRPDV---G 177
Query: 1437 AREDSLPEE--SSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVL 1494
++ DS+P S+ + H + +P P P PG + +
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG--GPRQPSPGPTPPPFPGNRGTALGGGSI 235
Query: 1495 RDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTV 1554
R SP F P T S + PPPPPPP P + PPPPP
Sbjct: 236 RQSPLS----SSSPFSNRPPLPPTPSRALDD-KPPPPPPPVGNRPSIHREAVPPPPPQ-- 288
Query: 1555 CEAQLDSEDPEGPRPS 1570
P PRPS
Sbjct: 289 ---NNKPPVPSTPRPS 301
Score = 43.9 bits (102), Expect = 0.002
Identities = 58/234 (24%), Positives = 75/234 (32%), Gaps = 13/234 (5%)
Query: 1324 RQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTP 1383
RQ S P P PP G +G + +P+ + P + + PP P
Sbjct: 211 RQPSPGPTP-PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 1384 AMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLP 1443
+ +R + H PP P P + + P PPPSR S
Sbjct: 270 PVGNRPSIHREAVPPPPPQ-NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328
Query: 1444 EESSAPDFANLKHYQKQQSLPSLCSTSD-PDTPLGAPSTPGRISLRISESVLRDSPPPHE 1502
+E+ NL LPS + P P P P R S + P
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388
Query: 1503 DYEDEVFVRDPHPKATS---SPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHT 1553
P + S SP P PP PP PS P PPPPP T
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP-------PPPPPST 435
Score = 42.0 bits (97), Expect = 0.006
Identities = 67/266 (25%), Positives = 89/266 (33%), Gaps = 51/266 (19%)
Query: 1308 GDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYC 1367
G VPS + + Q +R P PRP + G D+ P+ P+ S+ P
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDV----GSKPDSIPPPVPSTPRPIQSS-PHNRG 202
Query: 1368 SQDGQTG-RQPLPPYTPAMMHRSNGHTL-----------------TQPPGP----RGCEG 1405
S G RQP P TP + G L +PP P R +
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262
Query: 1406 DGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPS 1465
P G R + PPP P +++ P + PS
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPP--------------PPQNNKPPVPSTPR-------PS 301
Query: 1466 LCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEP 1525
S + P P PS PG L S S ++P + P P S P
Sbjct: 302 ASSQAPPPPP--PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359
Query: 1526 LPPPPPPPPSQETPVYSMDDFPPPPP 1551
P PPPP ++ P S PPPPP
Sbjct: 360 PPSERPPPPVRDPPGRS-GPLPPPPP 384
Score = 32.3 bits (72), Expect = 4.8
Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 11/122 (9%)
Query: 348 SNIPRGKGVPPPSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSL 407
+N P P PS S Q P + PP PLPP+ S + R +R S SS
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPP----PLPPSSSGNDETPRLPQRNLSLSSS 344
Query: 408 DQKRLCRPQANSLGSLKSPFIEEQLHTVLE----KSPENSPPVKPKHNYTQKAQPGQPLL 463
P G L P E V + P PP ++ T +A P P L
Sbjct: 345 TPPL---PSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401
Query: 464 PT 465
P+
Sbjct: 402 PS 403
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/226 (27%), Positives = 85/226 (37%), Gaps = 34/226 (15%)
Query: 1333 RPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPS-GYCSQDGQTGRQPLPPYTPAMMHRSNG 1391
RPPL G T A P +P P +PS G+ S + R +PP P + + +
Sbjct: 125 RPPLLPPGG--RSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDS 182
Query: 1392 HTLTQPPGPRGCEGDGPEHG---VEEGTRKRVSLPQWPPPSRAKWAHAAREDSL---PEE 1445
P PR + G V G R+ P PPP A S+ P
Sbjct: 183 IPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPT-PPPFPGNRGTALGGGSIRQSPLS 241
Query: 1446 SSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYE 1505
SS+P + + LP S + D P P G S+ R++ PP
Sbjct: 242 SSSP-------FSNRPPLPPTPSRALDDKPPPPPPPVGN-----RPSIHREAVPPPPPQN 289
Query: 1506 DEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPP 1551
++ P +T P+ PPPPPPPS+ P PP PP
Sbjct: 290 NK-----PPVPSTPRPSASSQAPPPPPPPSRPGP-------PPLPP 323
Score = 44.3 bits (103), Expect = 0.001
Identities = 50/196 (25%), Positives = 65/196 (33%), Gaps = 24/196 (12%)
Query: 1379 PPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEH--GVEEGTRKRVSLPQWPPPSRAKWAHA 1436
PP P ++ + P GP P H G E R R+ PPP
Sbjct: 126 PPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM-----PPPRPDV---G 177
Query: 1437 AREDSLPEE--SSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVL 1494
++ DS+P S+ + H + +P P P PG + +
Sbjct: 178 SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPG--GPRQPSPGPTPPPFPGNRGTALGGGSI 235
Query: 1495 RDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTV 1554
R SP F P T S + PPPPPPP P + PPPPP
Sbjct: 236 RQSPLS----SSSPFSNRPPLPPTPSRALDD-KPPPPPPPVGNRPSIHREAVPPPPPQ-- 288
Query: 1555 CEAQLDSEDPEGPRPS 1570
P PRPS
Sbjct: 289 ---NNKPPVPSTPRPS 301
Score = 43.9 bits (102), Expect = 0.002
Identities = 58/234 (24%), Positives = 75/234 (32%), Gaps = 13/234 (5%)
Query: 1324 RQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTP 1383
RQ S P P PP G +G + +P+ + P + + PP P
Sbjct: 211 RQPSPGPTP-PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 1384 AMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLP 1443
+ +R + H PP P P + + P PPPSR S
Sbjct: 270 PVGNRPSIHREAVPPPPPQ-NNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328
Query: 1444 EESSAPDFANLKHYQKQQSLPSLCSTSD-PDTPLGAPSTPGRISLRISESVLRDSPPPHE 1502
+E+ NL LPS + P P P P R S + P
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388
Query: 1503 DYEDEVFVRDPHPKATS---SPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHT 1553
P + S SP P PP PP PS P PPPPP T
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAP-------PPPPPST 435
Score = 42.0 bits (97), Expect = 0.006
Identities = 67/266 (25%), Positives = 89/266 (33%), Gaps = 51/266 (19%)
Query: 1308 GDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYC 1367
G VPS + + Q +R P PRP + G D+ P+ P+ S+ P
Sbjct: 148 GRFPVPSPGHRSGPPEPQRNRMPPPRPDV----GSKPDSIPPPVPSTPRPIQSS-PHNRG 202
Query: 1368 SQDGQTG-RQPLPPYTPAMMHRSNGHTL-----------------TQPPGP----RGCEG 1405
S G RQP P TP + G L +PP P R +
Sbjct: 203 SPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262
Query: 1406 DGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPS 1465
P G R + PPP P +++ P + PS
Sbjct: 263 KPPPPPPPVGNRPSIHREAVPPP--------------PPQNNKPPVPSTPR-------PS 301
Query: 1466 LCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEP 1525
S + P P PS PG L S S ++P + P P S P
Sbjct: 302 ASSQAPPPPP--PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPP 359
Query: 1526 LPPPPPPPPSQETPVYSMDDFPPPPP 1551
P PPPP ++ P S PPPPP
Sbjct: 360 PPSERPPPPVRDPPGRS-GPLPPPPP 384
Score = 32.3 bits (72), Expect = 4.8
Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 11/122 (9%)
Query: 348 SNIPRGKGVPPPSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSL 407
+N P P PS S Q P + PP PLPP+ S + R +R S SS
Sbjct: 289 NNKPPVPSTPRPSASSQAPPPPPPPSRPGPP----PLPPSSSGNDETPRLPQRNLSLSSS 344
Query: 408 DQKRLCRPQANSLGSLKSPFIEEQLHTVLE----KSPENSPPVKPKHNYTQKAQPGQPLL 463
P G L P E V + P PP ++ T +A P P L
Sbjct: 345 TPPL---PSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQL 401
Query: 464 PT 465
P+
Sbjct: 402 PS 403
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 52.4 bits (124), Expect = 4e-06
Identities = 76/290 (26%), Positives = 98/290 (33%), Gaps = 79/290 (27%)
Query: 1330 PCPRPPLAGTQGLVTD-------------TRAAPLTPIGTPLPS----AIPSGYCSQDGQ 1372
P P PP A + LVT T+AAP TP P+ A P+ Y
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 1373 TGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAK 1432
T P+PP T + + PP P P V + + P PP ++
Sbjct: 830 TPPVPVPPPT---LPKQQSFCAKPPPSPLS-----PVPSVVKQIASQFPPPPTPPAMESQ 881
Query: 1433 WAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISES 1492
+ P+ A +K K Q PS PD P P ES
Sbjct: 882 PLKPVPANVAPQSPPA-----VKAKPKWQ--PSSIPVPSPDFPPPPP-----------ES 923
Query: 1493 VLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMD-------- 1544
L PPP P+ P PPPPPPP + TP S
Sbjct: 924 SLVFPPPP--------------------PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT 963
Query: 1545 -----DFPPPPP--HTVCEAQLDSEDPEGPRPSFNKL-SKVTIARERHMP 1586
PPP P ++ ++ +E PE RPS + L SK T E P
Sbjct: 964 SSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Score = 40.4 bits (93), Expect = 0.018
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 12/66 (18%)
Query: 1513 PHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFN 1572
P+ + SP P PPPPPPPP PPPPP +Q + P F
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPP-----------PPPPPPPPLPSQ-SAPSAGSAAPMFV 665
Query: 1573 KLSKVT 1578
K S +T
Sbjct: 666 KYSTIT 671
Score = 36.6 bits (83), Expect = 0.25
Identities = 66/256 (25%), Positives = 83/256 (32%), Gaps = 51/256 (19%)
Query: 1313 PSECPGTLDHQRQASRTPC---------PRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIP 1363
P PG+ Q PC P PPL Q + T+ AP TP P P IP
Sbjct: 717 PPPTPGSA--MAQLKPAPCAPSLPQFSAPPPPLKIHQ-VQHITQVAPPTP---PPPPPIP 770
Query: 1364 SGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLP 1423
+ PLPP P L P P + P T+ P
Sbjct: 771 A------------PLPPQAPPK-------PLVTIPAPTSTKTVAPVV-----TQAAPPTP 806
Query: 1424 QWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPG 1483
P P K P + P KQQS C+ P PS
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF---CAKPPPSPLSPVPSVVK 863
Query: 1484 RISLRISESVLRDSPP-----PHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQET 1538
+I+ S+ +PP P + V + P P + P ++P P P P
Sbjct: 864 QIA---SQFPPPPTPPAMESQPLKPVPANVAPQSP-PAVKAKPKWQPSSIPVPSPDFPPP 919
Query: 1539 PVYSMDDFPPPPPHTV 1554
P S FPPPPP V
Sbjct: 920 PPESSLVFPPPPPSPV 935
Score = 34.3 bits (77), Expect = 1.3
Identities = 62/305 (20%), Positives = 102/305 (33%), Gaps = 41/305 (13%)
Query: 1330 PCPRPPLAGTQGLV-TDTRAAPLTPIGT-------PLPSAIPSGYCSQDGQTGRQPLPPY 1381
P P PP +Q L AP +P P +PS PP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 1382 TPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTR-KRVSLPQWPPPSRAKWAHAARED 1440
P+ + PP P P+ G + + S P P +++ +
Sbjct: 931 PPSPVP-------APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983
Query: 1441 SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDT--PLGAPSTPGRISLR-------ISE 1491
S E P ++ + + P+ + +T P AP PG+++L + +
Sbjct: 984 SSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQ 1043
Query: 1492 SVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPP-----PPSQETPVYSMDDF 1546
+ P + V P P P+ PPPPP PP + V+S +
Sbjct: 1044 GCVSAKAPVLSGRGKDSVVEFPSP-----PSDSDFPPPPPETELPLPPIEIPAVFSGNTS 1098
Query: 1547 PP-----PPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRL 1601
P P P + + + P RP N +++T A P A VV + +
Sbjct: 1099 PKVAVVNPQPQQWSKMSV-KKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKS 1157
Query: 1602 QTSIK 1606
S++
Sbjct: 1158 SLSVQ 1162
Score = 32.7 bits (73), Expect = 3.7
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 11/56 (19%)
Query: 1525 PLPPPPPPPPSQETPVYSMDDFP----------PPPPHTVCEAQ-LDSEDPEGPRP 1569
P PPPPPPPP+ + + + P PPPP + + Q + P P P
Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765
Score = 32.0 bits (71), Expect = 6.2
Identities = 16/48 (33%), Positives = 21/48 (43%), Gaps = 8/48 (16%)
Query: 1511 RDPHPKATSSPTFEP--------LPPPPPPPPSQETPVYSMDDFPPPP 1550
+ P P S + +P + PPPPPPP TP +M P P
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP 732
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 52.4 bits (124), Expect = 4e-06
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 10/100 (10%)
Query: 32 LEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSS-SRKE 90
L GGAPWGF L GG E +PL +SK+ +A + L+ D+++ IN V+ ++ S
Sbjct: 11 LSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAG--RAGLRERDQLLAINGVSCTNLSHAS 68
Query: 91 AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHL 130
A+SL+ S L L V+R AD G SP L
Sbjct: 69 AMSLIDASGNQLVLTVQR-------LADEGPVQSPSPHEL 101
Score = 38.5 bits (88), Expect = 0.067
Identities = 54/239 (22%), Positives = 82/239 (34%), Gaps = 29/239 (12%)
Query: 1308 GDSSVPSECPGTLDHQRQASRTPCPRP--PLAGTQGLVTDTRAAPLTPIGTPLPSAIPSG 1365
G + +PS G H + PR P+ T L + P+TP G P P A PS
Sbjct: 514 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSA 573
Query: 1366 YCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRG-CEGDGPEHGVEE---GTRKRVS 1421
A M + L+ P P E P G E +R+S
Sbjct: 574 ------------------AAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRIS 615
Query: 1422 LPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPST 1481
+ P +R AR ++ P K+ + L + + + GA S
Sbjct: 616 V----PAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESG 671
Query: 1482 PGRISLRI-SESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETP 1539
P +L + +E+ P Y+ V P + T P+ P PPP + + P
Sbjct: 672 PEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPP 730
Score = 33.1 bits (74), Expect = 2.8
Identities = 42/152 (27%), Positives = 55/152 (36%), Gaps = 28/152 (18%)
Query: 1515 PKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPS-FNK 1573
P+A S+P + PP P P PV S F P P PS FN+
Sbjct: 423 PRAQSAPPEAAVLPPSPLP----APVASPRPFQP------------GGGAPTPAPSIFNR 466
Query: 1574 LSK-VTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQLAGSLGGQP 1632
++ T + P V+ R S+ G PP F+S S G P
Sbjct: 467 SARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG--LSPAPPPFLS-------SQGPTP 517
Query: 1633 APIQTQSL-SHDPVSGTQGLEKKVSPDPQKSS 1663
P T + SH PVSG+ + P SS
Sbjct: 518 LPSFTSGVPSHAPVSGSPSTPRSSGPVTATSS 549
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 52.0 bits (123), Expect = 6e-06
Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 21/179 (11%)
Query: 4 TTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKA 63
TT+ + + AT+ + Y G +GF+L+GG E+ L + ++ E G A
Sbjct: 1099 TTKPKQESQFEFKAPQATQEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPA 1158
Query: 64 DTLSSKLQAGDEVVHIN-EVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
+ K++ GDE++ IN E T + A+ L+K + +RL ++R
Sbjct: 1159 ER-CGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKR-------------G 1204
Query: 123 NFVSPEHLTSGPQHRKAAWSGGVKL------RLKHRRSEPAGRPHSWHTTKSGEKQPDA 175
+ PE+ S +H A GV R +H E + P ++ GEK+ A
Sbjct: 1205 DGSVPEYDPSSDRHGPATGPQGVPEVRAGPDRRQHPSLESSYPPDLHKSSPHGEKRAHA 1263
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 16/135 (11%)
Query: 38 WGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEV-TLSSSRKEAVSLVK 96
+GF + GG E GEP+ I + G ADT +L++GDE++ ++ + S + V L++
Sbjct: 823 FGFRILGGNEPGEPIYIGHIVPLGAADT-DGRLRSGDELICVDGTPVIGKSHQLVVQLMQ 881
Query: 97 GSYKT--LRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRS 154
+ K + L VRR V F P+ P + S L +
Sbjct: 882 QAAKQGHVNLTVRRKVV------------FAVPKTENEVPSPASSHHSSNQPASLTEEKR 929
Query: 155 EPAGRPHSWHTTKSG 169
P G +S +T SG
Sbjct: 930 TPQGSQNSLNTVSSG 944
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 52.0 bits (123), Expect = 6e-06
Identities = 64/268 (23%), Positives = 96/268 (35%), Gaps = 37/268 (13%)
Query: 1323 QRQASRTPCPRPPLAGTQGLV---TDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLP 1379
Q +SR PRPP++ G TD+ A L + ++P +P
Sbjct: 114 QIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDL---------SRPNT 164
Query: 1380 PYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPP--PSRAKWAHAA 1437
+ M H S+ PP P G + P + + K + + P P+ + H
Sbjct: 165 TSSTGMKHSSSA----PPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPG 220
Query: 1438 RED--SLPEESSAPDFANLKHYQKQQSL----------PSLCSTSDPDTPLGAPSTPGR- 1484
RE + P P N++ QSL P + + T AP P R
Sbjct: 221 REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRH 280
Query: 1485 --ISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYS 1542
+ + V +PPP + P P A P+ PPPPPP +
Sbjct: 281 NSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNG----A 336
Query: 1543 MDDFPPPPPHTVCEAQLDSEDPEGPRPS 1570
D PPPPP+ + ++ S P PS
Sbjct: 337 RDAPPPPPPYRMHGSEPPSRGKPPPPPS 364
Score = 51.6 bits (122), Expect = 8e-06
Identities = 60/259 (23%), Positives = 81/259 (31%), Gaps = 38/259 (14%)
Query: 1320 LDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPL---PSAIPSGYCSQDGQTGRQ 1376
L ++ S RP + G+ + A P P G P+ +P +
Sbjct: 148 LPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREK 207
Query: 1377 PLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHA 1436
PLPP +H PP P + + G + P PPP +
Sbjct: 208 PLPPTPGQRLHPGR----EGPPAPPPVKPPPSPVNIRTGPSGQSLAP--PPPPYRQPPGV 261
Query: 1437 AREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRD 1496
S P SAP+ +H + P P P A +P +S R
Sbjct: 262 PNGPSSPTNESAPELPQ-RHNSLHRKTPGPVRGLAPPPPTSA--SPSLLSNR-------- 310
Query: 1497 SPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPP--------------PPPSQETPVYS 1542
PPP D P P + + PPPPP PPP TP
Sbjct: 311 PPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGP 370
Query: 1543 MDDFPPPPPHTVCEAQLDS 1561
PPPPP + DS
Sbjct: 371 ----PPPPPPPLRNGHRDS 385
Score = 39.3 bits (90), Expect = 0.039
Identities = 51/190 (26%), Positives = 72/190 (37%), Gaps = 39/190 (20%)
Query: 1525 PLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLD----SEDPEGPRPSF-------NK 1573
P+PPPPPPPP PPPP T +A + S D + R + K
Sbjct: 2 PIPPPPPPPPG------------PPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTK 49
Query: 1574 LSKVTIARERHMP------GAAHVVGSQTLASRLQTSI-KGSEAESTPPSFMSVHAQLAG 1626
L KVT +R P G++ GS A + + + +G + P LAG
Sbjct: 50 LKKVTNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAG 109
Query: 1627 SLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDKSLADIL 1686
Q P + PVS G PQ ++ R +L + Q SL D+
Sbjct: 110 KPALQ-IPSSRAAAPRPPVSAASG-------RPQDDTDSSRA-SLPELPRMQRPSLPDLS 160
Query: 1687 DPDSRLKTTM 1696
P++ T M
Sbjct: 161 RPNTTSSTGM 170
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 51.6 bits (122), Expect = 8e-06
Identities = 32/115 (27%), Positives = 58/115 (50%), Gaps = 2/115 (1%)
Query: 4 TTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKA 63
TT+ + + AT+ + Y G +GF+L+GG E+ L + ++ E G A
Sbjct: 1127 TTKPKQESQFEFKAPQATQEQDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPA 1186
Query: 64 DTLSSKLQAGDEVVHIN-EVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHA 117
+ K++ GDE++ IN E T + A+ L+K + +RL ++R + P +A
Sbjct: 1187 ER-CGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVPEYA 1240
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 16/135 (11%)
Query: 38 WGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEV-TLSSSRKEAVSLVK 96
+GF + GG E GEP+ I + G ADT +L++GDE++ ++ + S + V L++
Sbjct: 851 FGFRILGGNEPGEPIYIGHIVPLGAADT-DGRLRSGDELICVDGTPVIGKSHQLVVQLMQ 909
Query: 97 GSYKT--LRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRS 154
+ K + L VRR V F P+ P + S L +
Sbjct: 910 QAAKQGHVNLTVRRKVV------------FAVPKTENEVPSPASSHHSSNQPASLTEEKR 957
Query: 155 EPAGRPHSWHTTKSG 169
P G +S +T SG
Sbjct: 958 TPQGSQNSLNTVSSG 972
>gi|61743946 abl-interactor 1 isoform c [Homo sapiens]
Length = 452
Score = 51.2 bits (121), Expect = 1e-05
Identities = 58/255 (22%), Positives = 90/255 (35%), Gaps = 47/255 (18%)
Query: 1318 GTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQP 1377
GTL ++ P P PP++G L +T L P+ P +P+ Y + + G Q
Sbjct: 169 GTLSRTNPPTQKP-PSPPMSGRGTLGRNTPYKTLEPVKPP---TVPNDYMTSPARLGSQH 224
Query: 1378 LPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAA 1437
P T ++ R H+ G G G G +++P PP+
Sbjct: 225 SPGRTASLNQRPRTHS-----GSSGGSGSRENSG-SSSIGIPIAVPTPSPPTIGP----- 273
Query: 1438 REDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDS 1497
+AP A Y S +++ T G ++ + S +
Sbjct: 274 ---------AAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNG 324
Query: 1498 PPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEA 1557
P + S + P PPPPPP + P++ DD PPPPP
Sbjct: 325 GPLY-----------------SQNSIADSPTPPPPPPPDDIPMF--DDSPPPPP----PP 361
Query: 1558 QLDSEDPEGPRPSFN 1572
+D ED E +N
Sbjct: 362 PVDYEDEEAAVVQYN 376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,800,369
Number of Sequences: 37866
Number of extensions: 5789888
Number of successful extensions: 39205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 1058
Number of HSP's that attempted gapping in prelim test: 25472
Number of HSP's gapped (non-prelim): 9587
length of query: 1996
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1879
effective length of database: 13,817,196
effective search space: 25962511284
effective search space used: 25962511284
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.