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Search of human proteins with 18152779
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
(575 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18152779 scavenger receptor cysteine rich domain containing, ... 1239 0.0
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 515 e-146
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 515 e-146
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 515 e-146
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 512 e-145
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 511 e-145
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 430 e-120
gi|44889963 CD163 antigen isoform b [Homo sapiens] 338 1e-92
gi|44662834 CD163 antigen isoform a [Homo sapiens] 338 1e-92
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 337 1e-92
gi|4506143 neurotrypsin precursor [Homo sapiens] 328 6e-90
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 267 2e-71
gi|5174411 CD5 molecule-like [Homo sapiens] 257 2e-68
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 251 2e-66
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 225 7e-59
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 224 2e-58
gi|194018748 CD6 molecule [Homo sapiens] 174 2e-43
gi|5031863 galectin 3 binding protein [Homo sapiens] 115 1e-25
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 112 1e-24
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 108 1e-23
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 105 9e-23
gi|5803080 macrophage receptor with collagenous structure [Homo ... 103 3e-22
gi|166197668 CD5 molecule [Homo sapiens] 86 1e-16
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo... 46 1e-04
gi|58761492 Rho guanine nucleotide exchange factor (GEF) 10-like... 37 0.038
gi|74136547 Rho guanine nucleotide exchange factor (GEF) 10-like... 37 0.038
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 36 0.084
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap... 36 0.084
gi|239754935 PREDICTED: hypothetical protein [Homo sapiens] 36 0.11
gi|239749477 PREDICTED: hypothetical protein XP_002347062 [Homo ... 36 0.11
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 1239 bits (3205), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MHKEAEMLIGPQLDEKRWGWRLGDGSAAPPFLPQALSFLLLLPLASALQPTPLPFQELRL 60
MHKEAEMLIGPQLDEKRWGWRLGDGSAAPPFLPQALSFLLLLPLASALQPTPLPFQELRL
Sbjct: 1 MHKEAEMLIGPQLDEKRWGWRLGDGSAAPPFLPQALSFLLLLPLASALQPTPLPFQELRL 60
Query: 61 VGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPI 120
VGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPI
Sbjct: 61 VGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPI 120
Query: 121 LLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTL 180
LLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTL
Sbjct: 121 LLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTL 180
Query: 181 PNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATT 240
PNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATT
Sbjct: 181 PNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATT 240
Query: 241 NAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALP 300
NAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALP
Sbjct: 241 NAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALP 300
Query: 301 SSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVL 360
SSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVL
Sbjct: 301 SSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVL 360
Query: 361 HAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARL 420
HAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARL
Sbjct: 361 HAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARL 420
Query: 421 SDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAH 480
SDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAH
Sbjct: 421 SDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAH 480
Query: 481 RCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNV 540
RCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNV
Sbjct: 481 RCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNV 540
Query: 541 KCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
KCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS
Sbjct: 541 KCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 515 bits (1327), Expect = e-146
Identities = 262/534 (49%), Positives = 314/534 (58%), Gaps = 28/534 (5%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102
P + A P LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG
Sbjct: 837 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 896
Query: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
A P FGQG GPI+LD+V C G E+ L C GW HNC H ED V+C
Sbjct: 897 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 956
Query: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222
P+ L + P + +S ++RLV G + CQGRVE+L+ G WGTVCDD W D
Sbjct: 957 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 1016
Query: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282
A VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW HNCGH E
Sbjct: 1017 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSE 1076
Query: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342
DAG +C SA+ P PS +T + A+ A + S
Sbjct: 1077 DAGVIC--------------------------SASQSRPTPSPDTWPTSHASTAGSESSL 1110
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G
Sbjct: 1111 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1170
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ + D T+
Sbjct: 1171 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSH 1229
Query: 463 VPTPRPRDG-HLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALA 521
T LRLVNG RC+GRVE+ WGTVCDD WD A V+CRQLGCG A +
Sbjct: 1230 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1289
Query: 522 APGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
APG A FG G GPI+LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 1290 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1343
Score = 514 bits (1323), Expect = e-145
Identities = 258/529 (48%), Positives = 315/529 (59%), Gaps = 46/529 (8%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A P FGQG
Sbjct: 592 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 651
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C + GW HNC H+ED V+C P L++ P
Sbjct: 652 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLP 711
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G++ CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 712 PSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 771
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 772 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 822
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
S + P PS +T + A+ A + S LRLV G C+GRV
Sbjct: 823 -----------------SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRV 865
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD +DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 866 EVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYE 925
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEE-----------LGLQVQQDGSETTRVPTP 466
+ L C H GW HNC H EDAG +C+ + L GSE++
Sbjct: 926 SYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLA--- 982
Query: 467 RPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526
LRLVNG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A
Sbjct: 983 ------LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 1036
Query: 527 HFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
FG G GPI+LD+V+C G ES L C H W +HNC HSEDA V+C S
Sbjct: 1037 RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 1085
Score = 512 bits (1318), Expect = e-145
Identities = 266/546 (48%), Positives = 317/546 (58%), Gaps = 47/546 (8%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RC+GR+EV++ GSWG+VCDD WD
Sbjct: 1213 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1272
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1273 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1332
Query: 150 YEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGL 209
+ED V+C PT T + +S ++RLV G + CQGRVE+L+ G
Sbjct: 1333 HEDAGVICSA--SQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGS 1390
Query: 210 WGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQ 269
WGTVCDD W DA VVCRQLGCG A +A NA FG G+G I+LD+V C G E L +C
Sbjct: 1391 WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 1450
Query: 270 SLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETAL 329
GW HNCGHHEDAG +C SA+ P PS +T
Sbjct: 1451 HNGWLSHNCGHHEDAGVIC--------------------------SASQSQPTPSPDTWP 1484
Query: 330 LTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGP 389
+ A+ A + + LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GCG
Sbjct: 1485 TSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 1544
Query: 390 ALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449
A+ A G FG G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1545 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 1604
Query: 450 GLQVQQDGSETTRVP---TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRA 506
+ D TT +P LRLVNG RC GRVE+ WGTVCDD+WD
Sbjct: 1605 STP-RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTND 1663
Query: 507 AGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSE 566
A V+CRQLGCG A++APG A FG G GPI+LD+V+C G ES L C H W HNC H E
Sbjct: 1664 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHE 1723
Query: 567 DASVLC 572
DA V+C
Sbjct: 1724 DAGVIC 1729
Score = 511 bits (1315), Expect = e-145
Identities = 260/519 (50%), Positives = 309/519 (59%), Gaps = 30/519 (5%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 983 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1042
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C PT T
Sbjct: 1043 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSA--SQSRPTPSPDTWPTSH 1100
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM+
Sbjct: 1101 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1160
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 1161 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 1211
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
SA+ P PS +T + A+ A + S LRLV G C+GRV
Sbjct: 1212 -----------------SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1254
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 1255 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1314
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476
+ L C H GW HNCGHHEDAG +C+ + D T+ T LRLV
Sbjct: 1315 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHASTAGSESSLALRLV 1373
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
NG RC+GRVE+ WGTVCDD WD A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 1374 NGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV 1433
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 1434 LDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1472
Score = 509 bits (1310), Expect = e-144
Identities = 262/538 (48%), Positives = 318/538 (59%), Gaps = 41/538 (7%)
Query: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96
L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC
Sbjct: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+
Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
Query: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215
C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
Query: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275
D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW
Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335
HNCGH EDAG +C SA P PS +T + A+
Sbjct: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
Query: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G
Sbjct: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGP-EELGLQVQ 454
FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+ + L
Sbjct: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLPTITLPAS 474
Query: 455 QDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQL 514
GSE++ LRLVNG RC+GRVE+ WGTVCDD+WD A V+CRQL
Sbjct: 475 TVGSESSLA---------LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 525
Query: 515 GCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
GCG A+ APG A FG G GPI+LD+V+C G ES L C H W +HNC HSEDA V+C
Sbjct: 526 GCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVIC 583
Score = 503 bits (1296), Expect = e-142
Identities = 255/516 (49%), Positives = 308/516 (59%), Gaps = 49/516 (9%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 484 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 543
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P
Sbjct: 544 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS----------------GPE 587
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
++L ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 588 SSL-------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 640
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C + GW HNCGHHEDAG +C +
Sbjct: 641 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC--------S 692
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
A S +T P+P + + + + S LRLV G C+GRV
Sbjct: 693 AAQSRST----------------PRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRV 736
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 737 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 796
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476
+ L C H GW HNCGHHEDAG +C+ + D T+ T P LRLV
Sbjct: 797 SYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP-SPDTWPTSHASTAGPESSLALRLV 855
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
NG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 856 NGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIV 915
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
LD+V+C G ES L C H W +HNC HSEDA V+C
Sbjct: 916 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 951
Score = 499 bits (1286), Expect = e-141
Identities = 257/535 (48%), Positives = 306/535 (57%), Gaps = 59/535 (11%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102
P + A P LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
A P FGQG GPI+LD+V C G E+ L C GW HNC H ED V+C + LP
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLP 467
Query: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222
T P + +S ++RLV G + CQGRVE+L+ G WGTVCDD W D
Sbjct: 468 T----------ITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTND 517
Query: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282
A VVCRQLGCG AM A NA FG G+G I+LD+V C G E L +C GW HNCGH E
Sbjct: 518 ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSE 577
Query: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342
DAG +C+G P S S
Sbjct: 578 DAGVICSG---------PES--------------------------------------SL 590
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G
Sbjct: 591 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 650
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C + GW HNCGHHEDAG +C+ + S T
Sbjct: 651 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 710
Query: 463 VPTPRPRDGH--LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQAL 520
P+ + LRLVNG+ RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A
Sbjct: 711 PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 770
Query: 521 AAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
+APG A FG G GPI+LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 771 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVS 825
Score = 389 bits (998), Expect = e-108
Identities = 206/420 (49%), Positives = 245/420 (58%), Gaps = 45/420 (10%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RC+GR+EV++ GSWG+VCDD WD
Sbjct: 1342 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1401
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1402 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1461
Query: 150 YEDVAVLCD--EFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHS 207
+ED V+C + PT P TSRA + +S ++RLV G + C+GRVE+L+
Sbjct: 1462 HEDAGVICSASQSQPTPSPDT-WPTSRA---STAGSESTLALRLVNGGDRCRGRVEVLYQ 1517
Query: 208 GLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAA 267
G WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +
Sbjct: 1518 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 1577
Query: 268 CQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRET 327
C GW HNCGHHEDAG +C+ A S R D T+ A VG + S
Sbjct: 1578 CPHNGWLSHNCGHHEDAGVICSA-------AQSQSTPRPDTWLTTNLPALTVGSESSLA- 1629
Query: 328 ALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC 387
LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GC
Sbjct: 1630 ----------------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 1673
Query: 388 GPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447
G A+ A G FG G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1674 GWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1733
Score = 271 bits (693), Expect = 1e-72
Identities = 141/289 (48%), Positives = 170/289 (58%), Gaps = 26/289 (8%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RCRGR+EV++ GSWG+VCDD WD
Sbjct: 1471 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1530
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A+ P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1531 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1590
Query: 150 YEDVAVLCDEFLPTQPPTRKM-LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208
+ED V+C P LT+ P T+ +S ++RLV G + C+GRVE+L+ G
Sbjct: 1591 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTV-GSESSLALRLVNGGDRCRGRVEVLYRG 1649
Query: 209 LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAAC 268
WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C
Sbjct: 1650 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 1709
Query: 269 QSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSAT 317
GW HNCGHHEDAG +C +A ++T DW W + T
Sbjct: 1710 PHKGWLTHNCGHHEDAGVIC--------SATQINSTTTDW-WHPTTTTT 1749
Score = 132 bits (332), Expect = 9e-31
Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
Query: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241
S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N
Sbjct: 1869 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1928
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G
Sbjct: 1929 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1977
Score = 129 bits (325), Expect = 6e-30
Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)
Query: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 1868 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1927
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C
Sbjct: 1928 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1975
Score = 126 bits (317), Expect = 5e-29
Identities = 52/95 (54%), Positives = 64/95 (67%)
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410
G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+
Sbjct: 1883 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1942
Query: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
V C+GTE+ L C + GW HNC H EDAG +C+G
Sbjct: 1943 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1977
Score = 121 bits (304), Expect = 2e-27
Identities = 51/91 (56%), Positives = 63/91 (69%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE
Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1944
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
C G E+ L +C +RGW HNC H ED V+C
Sbjct: 1945 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1975
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 515 bits (1327), Expect = e-146
Identities = 262/534 (49%), Positives = 314/534 (58%), Gaps = 28/534 (5%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102
P + A P LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG
Sbjct: 847 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 906
Query: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
A P FGQG GPI+LD+V C G E+ L C GW HNC H ED V+C
Sbjct: 907 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 966
Query: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222
P+ L + P + +S ++RLV G + CQGRVE+L+ G WGTVCDD W D
Sbjct: 967 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 1026
Query: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282
A VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW HNCGH E
Sbjct: 1027 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSE 1086
Query: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342
DAG +C SA+ P PS +T + A+ A + S
Sbjct: 1087 DAGVIC--------------------------SASQSRPTPSPDTWPTSHASTAGSESSL 1120
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G
Sbjct: 1121 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1180
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ + D T+
Sbjct: 1181 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSH 1239
Query: 463 VPTPRPRDG-HLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALA 521
T LRLVNG RC+GRVE+ WGTVCDD WD A V+CRQLGCG A +
Sbjct: 1240 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1299
Query: 522 APGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
APG A FG G GPI+LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 1300 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1353
Score = 514 bits (1323), Expect = e-145
Identities = 258/529 (48%), Positives = 315/529 (59%), Gaps = 46/529 (8%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A P FGQG
Sbjct: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C + GW HNC H+ED V+C P L++ P
Sbjct: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLP 721
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G++ CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 722 PSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 781
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 782 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 832
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
S + P PS +T + A+ A + S LRLV G C+GRV
Sbjct: 833 -----------------SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRV 875
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD +DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 876 EVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYE 935
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEE-----------LGLQVQQDGSETTRVPTP 466
+ L C H GW HNC H EDAG +C+ + L GSE++
Sbjct: 936 SYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLA--- 992
Query: 467 RPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526
LRLVNG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A
Sbjct: 993 ------LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 1046
Query: 527 HFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
FG G GPI+LD+V+C G ES L C H W +HNC HSEDA V+C S
Sbjct: 1047 RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 1095
Score = 512 bits (1318), Expect = e-145
Identities = 266/546 (48%), Positives = 317/546 (58%), Gaps = 47/546 (8%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RC+GR+EV++ GSWG+VCDD WD
Sbjct: 1223 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1282
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1283 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1342
Query: 150 YEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGL 209
+ED V+C PT T + +S ++RLV G + CQGRVE+L+ G
Sbjct: 1343 HEDAGVICSA--SQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGS 1400
Query: 210 WGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQ 269
WGTVCDD W DA VVCRQLGCG A +A NA FG G+G I+LD+V C G E L +C
Sbjct: 1401 WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 1460
Query: 270 SLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETAL 329
GW HNCGHHEDAG +C SA+ P PS +T
Sbjct: 1461 HNGWLSHNCGHHEDAGVIC--------------------------SASQSQPTPSPDTWP 1494
Query: 330 LTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGP 389
+ A+ A + + LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GCG
Sbjct: 1495 TSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 1554
Query: 390 ALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449
A+ A G FG G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1555 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 1614
Query: 450 GLQVQQDGSETTRVP---TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRA 506
+ D TT +P LRLVNG RC GRVE+ WGTVCDD+WD
Sbjct: 1615 STP-RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTND 1673
Query: 507 AGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSE 566
A V+CRQLGCG A++APG A FG G GPI+LD+V+C G ES L C H W HNC H E
Sbjct: 1674 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHE 1733
Query: 567 DASVLC 572
DA V+C
Sbjct: 1734 DAGVIC 1739
Score = 511 bits (1315), Expect = e-145
Identities = 260/519 (50%), Positives = 309/519 (59%), Gaps = 30/519 (5%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 993 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1052
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C PT T
Sbjct: 1053 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSA--SQSRPTPSPDTWPTSH 1110
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM+
Sbjct: 1111 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1170
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 1171 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 1221
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
SA+ P PS +T + A+ A + S LRLV G C+GRV
Sbjct: 1222 -----------------SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1264
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 1265 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1324
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476
+ L C H GW HNCGHHEDAG +C+ + D T+ T LRLV
Sbjct: 1325 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHASTAGSESSLALRLV 1383
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
NG RC+GRVE+ WGTVCDD WD A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 1384 NGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV 1443
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 1444 LDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1482
Score = 506 bits (1303), Expect = e-143
Identities = 262/548 (47%), Positives = 318/548 (58%), Gaps = 51/548 (9%)
Query: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96
L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC
Sbjct: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+
Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
Query: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215
C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
Query: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275
D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW
Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335
HNCGH EDAG +C SA P PS +T + A+
Sbjct: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
Query: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G
Sbjct: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEE------- 448
FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+
Sbjct: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPD 474
Query: 449 ----LGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDL 504
+ L GSE++ LRLVNG RC+GRVE+ WGTVCDD+WD
Sbjct: 475 TLPTITLPASTVGSESSLA---------LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 525
Query: 505 RAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564
A V+CRQLGCG A+ APG A FG G GPI+LD+V+C G ES L C H W +HNC H
Sbjct: 526 NDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGH 585
Query: 565 SEDASVLC 572
SEDA V+C
Sbjct: 586 SEDAGVIC 593
Score = 503 bits (1296), Expect = e-142
Identities = 255/516 (49%), Positives = 308/516 (59%), Gaps = 49/516 (9%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P
Sbjct: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS----------------GPE 597
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
++L ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 598 SSL-------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C + GW HNCGHHEDAG +C +
Sbjct: 651 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC--------S 702
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
A S +T P+P + + + + S LRLV G C+GRV
Sbjct: 703 AAQSRST----------------PRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRV 746
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 747 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 806
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476
+ L C H GW HNCGHHEDAG +C+ + D T+ T P LRLV
Sbjct: 807 SYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP-SPDTWPTSHASTAGPESSLALRLV 865
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
NG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 866 NGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIV 925
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
LD+V+C G ES L C H W +HNC HSEDA V+C
Sbjct: 926 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 961
Score = 501 bits (1291), Expect = e-142
Identities = 253/515 (49%), Positives = 302/515 (58%), Gaps = 47/515 (9%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RCRGR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P PT T
Sbjct: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSA--PQSRPTPSPDTWPTSH 351
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 352 ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNC H EDAG +C+
Sbjct: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH----- 466
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
+W T P P + A+ + S LRLV G C+GRV
Sbjct: 467 -----------SWST--------PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRV 507
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G E
Sbjct: 508 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNE 567
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477
+ L C H GW HNCGH EDAG +C+GPE LRLVN
Sbjct: 568 SYLWSCPHNGWLSHNCGHSEDAGVICSGPES---------------------SLALRLVN 606
Query: 478 GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537
G RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A +APG A FG G GPI+L
Sbjct: 607 GGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVL 666
Query: 538 DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
D+V+C G ES L C + W +HNC H EDA V+C
Sbjct: 667 DDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 701
Score = 501 bits (1289), Expect = e-142
Identities = 256/535 (47%), Positives = 306/535 (57%), Gaps = 49/535 (9%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102
P + A P LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
A P FGQG GPI+LD+V C G E+ L C GW HNC H ED V+C
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222
P+ L + P + +S ++RLV G + CQGRVE+L+ G WGTVCDD W D
Sbjct: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTND 527
Query: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282
A VVCRQLGCG AM A NA FG G+G I+LD+V C G E L +C GW HNCGH E
Sbjct: 528 ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSE 587
Query: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342
DAG +C+G P S S
Sbjct: 588 DAGVICSG---------PES--------------------------------------SL 600
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G
Sbjct: 601 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C + GW HNCGHHEDAG +C+ + S T
Sbjct: 661 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
Query: 463 VPTPRPRDGH--LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQAL 520
P+ + LRLVNG+ RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A
Sbjct: 721 PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
Query: 521 AAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
+APG A FG G GPI+LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 781 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVS 835
Score = 389 bits (998), Expect = e-108
Identities = 206/420 (49%), Positives = 245/420 (58%), Gaps = 45/420 (10%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RC+GR+EV++ GSWG+VCDD WD
Sbjct: 1352 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1411
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1412 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1471
Query: 150 YEDVAVLCD--EFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHS 207
+ED V+C + PT P TSRA + +S ++RLV G + C+GRVE+L+
Sbjct: 1472 HEDAGVICSASQSQPTPSPDT-WPTSRA---STAGSESTLALRLVNGGDRCRGRVEVLYQ 1527
Query: 208 GLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAA 267
G WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +
Sbjct: 1528 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 1587
Query: 268 CQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRET 327
C GW HNCGHHEDAG +C+ A S R D T+ A VG + S
Sbjct: 1588 CPHNGWLSHNCGHHEDAGVICSA-------AQSQSTPRPDTWLTTNLPALTVGSESSLA- 1639
Query: 328 ALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC 387
LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GC
Sbjct: 1640 ----------------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 1683
Query: 388 GPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447
G A+ A G FG G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1684 GWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1743
Score = 271 bits (693), Expect = 1e-72
Identities = 141/289 (48%), Positives = 170/289 (58%), Gaps = 26/289 (8%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RCRGR+EV++ GSWG+VCDD WD
Sbjct: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1540
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A+ P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 1541 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600
Query: 150 YEDVAVLCDEFLPTQPPTRKM-LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208
+ED V+C P LT+ P T+ +S ++RLV G + C+GRVE+L+ G
Sbjct: 1601 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTV-GSESSLALRLVNGGDRCRGRVEVLYRG 1659
Query: 209 LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAAC 268
WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C
Sbjct: 1660 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 1719
Query: 269 QSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSAT 317
GW HNCGHHEDAG +C +A ++T DW W + T
Sbjct: 1720 PHKGWLTHNCGHHEDAGVIC--------SATQINSTTTDW-WHPTTTTT 1759
Score = 132 bits (332), Expect = 9e-31
Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
Query: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241
S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G
Sbjct: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
Score = 129 bits (325), Expect = 6e-30
Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)
Query: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 1878 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1937
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C
Sbjct: 1938 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
Score = 126 bits (317), Expect = 5e-29
Identities = 52/95 (54%), Positives = 64/95 (67%)
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410
G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+
Sbjct: 1893 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1952
Query: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
V C+GTE+ L C + GW HNC H EDAG +C+G
Sbjct: 1953 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
Score = 121 bits (304), Expect = 2e-27
Identities = 51/91 (56%), Positives = 63/91 (69%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE
Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
C G E+ L +C +RGW HNC H ED V+C
Sbjct: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
>gi|148539840 deleted in malignant brain tumors 1 isoform a
precursor [Homo sapiens]
Length = 1785
Score = 515 bits (1327), Expect = e-146
Identities = 262/534 (49%), Positives = 314/534 (58%), Gaps = 28/534 (5%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102
P + A P LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
A P FGQG GPI+LD+V C G E+ L C GW HNC H ED V+C
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222
P+ L + P + +S ++RLV G + CQGRVE+L+ G WGTVCDD W D
Sbjct: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 527
Query: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282
A VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW HNCGH E
Sbjct: 528 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSE 587
Query: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342
DAG +C SA+ P PS +T + A+ A + S
Sbjct: 588 DAGVIC--------------------------SASQSRPTPSPDTWPTSHASTAGSESSL 621
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G
Sbjct: 622 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 681
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ + D T+
Sbjct: 682 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSH 740
Query: 463 VPTPRPRDG-HLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALA 521
T LRLVNG RC+GRVE+ WGTVCDD WD A V+CRQLGCG A +
Sbjct: 741 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 800
Query: 522 APGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
APG A FG G GPI+LD+V+C G ES L C H W +HNC H EDA V+C S
Sbjct: 801 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 854
Score = 512 bits (1318), Expect = e-145
Identities = 259/518 (50%), Positives = 311/518 (60%), Gaps = 32/518 (6%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 623 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 682
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H+ED V+C PT T
Sbjct: 683 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA--SQSQPTPSPDTWPTSH 740
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 741 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 800
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 801 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 851
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
SA+ P PS +T + A+ A + + LRLV G CRGRV
Sbjct: 852 -----------------SASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRV 894
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G E
Sbjct: 895 EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 954
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVP---TPRPRDGHLR 474
+ L C H GW HNCGHHEDAG +C+ + + D TT +P LR
Sbjct: 955 SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP-RPDTWLTTNLPALTVGSESSLALR 1013
Query: 475 LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534
LVNG RC GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A FG G GP
Sbjct: 1014 LVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 1073
Query: 535 ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
I+LD+V+C G ES L C H W HNC H EDA V+C
Sbjct: 1074 IVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1111
Score = 508 bits (1308), Expect = e-144
Identities = 263/551 (47%), Positives = 320/551 (58%), Gaps = 51/551 (9%)
Query: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96
L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC
Sbjct: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+
Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
Query: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215
C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
Query: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275
D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW
Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335
HNCGH EDAG +C SA P PS +T + A+
Sbjct: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
Query: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G
Sbjct: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEE------- 448
FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+
Sbjct: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPD 474
Query: 449 ----LGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDL 504
+ L GSE++ LRLVNG RC+GRVE+ WGTVCDD+WD
Sbjct: 475 TLPTITLPASTVGSESSLA---------LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 525
Query: 505 RAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564
A V+CRQLGCG A++APG A FG G GPI+LD+V+C G ES L C H W +HNC H
Sbjct: 526 NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 585
Query: 565 SEDASVLCQPS 575
SEDA V+C S
Sbjct: 586 SEDAGVICSAS 596
Score = 389 bits (998), Expect = e-108
Identities = 206/420 (49%), Positives = 245/420 (58%), Gaps = 45/420 (10%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RC+GR+EV++ GSWG+VCDD WD
Sbjct: 724 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 783
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 784 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 843
Query: 150 YEDVAVLCD--EFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHS 207
+ED V+C + PT P TSRA + +S ++RLV G + C+GRVE+L+
Sbjct: 844 HEDAGVICSASQSQPTPSPDT-WPTSRA---STAGSESTLALRLVNGGDRCRGRVEVLYQ 899
Query: 208 GLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAA 267
G WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +
Sbjct: 900 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 959
Query: 268 CQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRET 327
C GW HNCGHHEDAG +C+ A S R D T+ A VG + S
Sbjct: 960 CPHNGWLSHNCGHHEDAGVICSA-------AQSQSTPRPDTWLTTNLPALTVGSESSLA- 1011
Query: 328 ALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC 387
LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GC
Sbjct: 1012 ----------------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 1055
Query: 388 GPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447
G A+ A G FG G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1056 GWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1115
Score = 271 bits (693), Expect = 1e-72
Identities = 141/289 (48%), Positives = 170/289 (58%), Gaps = 26/289 (8%)
Query: 45 ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89
AS QPTP P LRLV G RCRGR+EV++ GSWG+VCDD WD
Sbjct: 853 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 912
Query: 90 VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149
DANVVCRQLGCG A+ P FGQG GPI+LD+V C G E+ L C GW HNC H
Sbjct: 913 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 972
Query: 150 YEDVAVLCDEFLPTQPPTRKM-LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208
+ED V+C P LT+ P T+ +S ++RLV G + C+GRVE+L+ G
Sbjct: 973 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTV-GSESSLALRLVNGGDRCRGRVEVLYRG 1031
Query: 209 LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAAC 268
WGTVCDD W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C
Sbjct: 1032 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 1091
Query: 269 QSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSAT 317
GW HNCGHHEDAG +C +A ++T DW W + T
Sbjct: 1092 PHKGWLTHNCGHHEDAGVIC--------SATQINSTTTDW-WHPTTTTT 1131
Score = 132 bits (332), Expect = 9e-31
Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
Query: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241
S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1310
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G
Sbjct: 1311 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1359
Score = 129 bits (325), Expect = 6e-30
Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)
Query: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 1250 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1309
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C
Sbjct: 1310 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1357
Score = 126 bits (317), Expect = 5e-29
Identities = 52/95 (54%), Positives = 64/95 (67%)
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410
G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+
Sbjct: 1265 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1324
Query: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
V C+GTE+ L C + GW HNC H EDAG +C+G
Sbjct: 1325 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1359
Score = 121 bits (304), Expect = 2e-27
Identities = 51/91 (56%), Positives = 63/91 (69%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE
Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1326
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
C G E+ L +C +RGW HNC H ED V+C
Sbjct: 1327 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1357
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 512 bits (1319), Expect = e-145
Identities = 258/519 (49%), Positives = 312/519 (60%), Gaps = 25/519 (4%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A P FGQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P+ L + P
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM
Sbjct: 483 ASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAML 542
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGH EDAG +C+ L
Sbjct: 543 APGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS-----ALQ 597
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
LP+ W PS+ + E++L LRLV G C+GRV
Sbjct: 598 WLPTPIRPRSW-----PSSHALQTCKGPESSL-------------ALRLVNGGDRCQGRV 639
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E
Sbjct: 640 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 699
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476
+ L C + GW HNCGHHEDAG +C+ + + D T+ T LRLV
Sbjct: 700 SYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP-RPDTWPTSHASTAGSESSLALRLV 758
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
NG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A FG G GPI+
Sbjct: 759 NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 818
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
LD+V+C G ES L C H W +HNC HSEDA V+C S
Sbjct: 819 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 857
Score = 512 bits (1319), Expect = e-145
Identities = 263/535 (49%), Positives = 316/535 (59%), Gaps = 34/535 (6%)
Query: 43 PLASALQPTPLPFQEL--RLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLG 100
P + ALQ P L RLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLG
Sbjct: 609 PSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 668
Query: 101 CGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEF 160
CG A P FGQG GPI+LD+V C G E+ L C + GW HNC H+ED V+C
Sbjct: 669 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAA 728
Query: 161 LPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGL 220
P + T +S ++RLV G + CQGRVE+L+ G WGTVCDD W
Sbjct: 729 QSRSTPRPDTWPTSHASTA--GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 786
Query: 221 PDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGH 280
DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW HNCGH
Sbjct: 787 NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 846
Query: 281 HEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKK 340
EDAG +C SA+ P PS +T + A+ A +
Sbjct: 847 SEDAGVIC--------------------------SASQSRPTPSPDTWPTSRASTAGSES 880
Query: 341 SGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFG 400
+ LRLV G CRGRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG
Sbjct: 881 TLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 940
Query: 401 YGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSET 460
G GP++LD+V C+G E+ L C H GW HNCGHHEDAG +C+ + + D T
Sbjct: 941 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP-RPDTWLT 999
Query: 461 TRVP---TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCG 517
T +P LRLVNG RC GRVE+ WGTVCDD+WD A V+CRQLGCG
Sbjct: 1000 TNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 1059
Query: 518 QALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A++APG A FG G GPI+LD+V+C G ES L C H W HNC H EDA V+C
Sbjct: 1060 WAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1114
Score = 507 bits (1305), Expect = e-143
Identities = 262/548 (47%), Positives = 318/548 (58%), Gaps = 51/548 (9%)
Query: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96
L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC
Sbjct: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+
Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
Query: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215
C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
Query: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275
D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW
Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335
HNCGH EDAG +C SA P PS +T + A+
Sbjct: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
Query: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G
Sbjct: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEE------- 448
FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+
Sbjct: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPD 474
Query: 449 ----LGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDL 504
+ L GSE++ LRLVNG RC+GRVE+ WGTVCDD+WD
Sbjct: 475 TLPTITLPASTVGSESSLA---------LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 525
Query: 505 RAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564
A V+CRQLGCG A+ APG A FG G GPI+LD+V+C G ES L C H W +HNC H
Sbjct: 526 NDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGH 585
Query: 565 SEDASVLC 572
SEDA V+C
Sbjct: 586 SEDAGVIC 593
Score = 388 bits (997), Expect = e-108
Identities = 199/392 (50%), Positives = 238/392 (60%), Gaps = 30/392 (7%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 755 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 814
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD--EFLPTQPPTRKMLTSRA 175
GPI+LD+V C G E+ L C GW HNC H ED V+C + PT P TSRA
Sbjct: 815 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT-WPTSRA 873
Query: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235
+ +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG A
Sbjct: 874 ---STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930
Query: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295
M+A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C+
Sbjct: 931 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA----- 985
Query: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355
A S R D T+ A VG + S LRLV G CRG
Sbjct: 986 --AQSQSTPRPDTWLTTNLPALTVGSESSLA-----------------LRLVNGGDRCRG 1026
Query: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415
RVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G
Sbjct: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086
Query: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447
E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1118
Score = 270 bits (690), Expect = 3e-72
Identities = 134/261 (51%), Positives = 163/261 (62%), Gaps = 11/261 (4%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RCRGR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 884 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 943
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM-LTSRAP 176
GPI+LD+V C G E+ L C GW HNC H+ED V+C P LT+ P
Sbjct: 944 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLP 1003
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
T+ +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG AM
Sbjct: 1004 ALTV-GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1062
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 1063 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC-------- 1114
Query: 297 TALPSSATREDWAWQTDPSAT 317
+A ++T DW W + T
Sbjct: 1115 SATQINSTTTDW-WHPTTTTT 1134
Score = 132 bits (332), Expect = 9e-31
Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
Query: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241
S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N
Sbjct: 1254 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1313
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G
Sbjct: 1314 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362
Score = 129 bits (325), Expect = 6e-30
Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)
Query: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 1253 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1312
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C
Sbjct: 1313 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360
Score = 126 bits (317), Expect = 5e-29
Identities = 52/95 (54%), Positives = 64/95 (67%)
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410
G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+
Sbjct: 1268 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1327
Query: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
V C+GTE+ L C + GW HNC H EDAG +C+G
Sbjct: 1328 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1362
Score = 121 bits (304), Expect = 2e-27
Identities = 51/91 (56%), Positives = 63/91 (69%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE
Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
C G E+ L +C +RGW HNC H ED V+C
Sbjct: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 511 bits (1316), Expect = e-145
Identities = 263/545 (48%), Positives = 318/545 (58%), Gaps = 39/545 (7%)
Query: 41 LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96
L+P S L+ T + LRLV G RC+GR+E+++ GSWG+VCDD WD DANVVC
Sbjct: 81 LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLGCG A+ P FGQG GPI LD+V C G E+ L C GW HNC H ED V+
Sbjct: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
Query: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215
C P + R +PP +S ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
Query: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275
D W DA VVCRQLGCG AM+A NA FG G+G I+LD+V C G E L +C GW
Sbjct: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
Query: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335
HNCGH EDAG +C SA P PS +T + A+
Sbjct: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
Query: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
A + S LRLV G C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A A G
Sbjct: 355 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQ 455
FG G GP++LD+V C+G E+ L C H GW HNC H EDAG +C+
Sbjct: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPG 474
Query: 456 DGSETTRVPT---PRPRDGH-----LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAA 507
+ T +PT P G LRLVNG RC+GRVE+ WGTVCDD+WD A
Sbjct: 475 ERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 534
Query: 508 GVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSED 567
V+CRQLGCG A+ APG A FG G GPI+LD+V+C G ES L C H W +HNC HSED
Sbjct: 535 NVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED 594
Query: 568 ASVLC 572
A V+C
Sbjct: 595 AGVIC 599
Score = 509 bits (1312), Expect = e-144
Identities = 258/518 (49%), Positives = 309/518 (59%), Gaps = 32/518 (6%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 500 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 559
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P +
Sbjct: 560 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHAS 619
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
T +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM+
Sbjct: 620 TA--GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 677
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNCGH EDAG +C
Sbjct: 678 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVIC--------- 728
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
SA+ P PS +T + A+ A + + LRLV G CRGRV
Sbjct: 729 -----------------SASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRV 771
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G E
Sbjct: 772 EVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 831
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVP---TPRPRDGHLR 474
+ L C H GW HNCGHHEDAG +C+ + + D TT +P LR
Sbjct: 832 SYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP-RPDTWLTTNLPALTVGSESSLALR 890
Query: 475 LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534
LVNG RC GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A FG G GP
Sbjct: 891 LVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 950
Query: 535 ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
I+LD+V+C G ES L C H W HNC H EDA V+C
Sbjct: 951 IVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988
Score = 506 bits (1304), Expect = e-143
Identities = 260/520 (50%), Positives = 313/520 (60%), Gaps = 24/520 (4%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RCRGR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI+LD+V C G E+ L C GW HNC H ED V+C P PT T
Sbjct: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSA--PQSRPTPSPDTWPTSH 351
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
+ +S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG A +
Sbjct: 352 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
A NA FG G+G I+LD+V C G E L +C GW HNC H EDAG +C+
Sbjct: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS---W 468
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG-RLRLVGGPGPCRGR 356
+ PS R+ +TD T +T A G +S LRLV G C+GR
Sbjct: 469 STPSPGERD----RTDTLPT------------ITLPASTVGSESSLALRLVNGGDRCQGR 512
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G
Sbjct: 513 VEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGN 572
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRL 475
E+ L C H GW HNCGH EDAG +C+ + + D T+ T LRL
Sbjct: 573 ESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTP-RPDTWPTSHASTAGSESSLALRL 631
Query: 476 VNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPI 535
VNG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A++APG A FG G GPI
Sbjct: 632 VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPI 691
Query: 536 LLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
+LD+V+C G ES L C H W +HNC HSEDA V+C S
Sbjct: 692 VLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 731
Score = 388 bits (997), Expect = e-108
Identities = 199/392 (50%), Positives = 238/392 (60%), Gaps = 30/392 (7%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 629 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 688
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD--EFLPTQPPTRKMLTSRA 175
GPI+LD+V C G E+ L C GW HNC H ED V+C + PT P TSRA
Sbjct: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT-WPTSRA 747
Query: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235
+ +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG A
Sbjct: 748 ---STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 804
Query: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295
M+A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C+
Sbjct: 805 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA----- 859
Query: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355
A S R D T+ A VG + S LRLV G CRG
Sbjct: 860 --AQSQSTPRPDTWLTTNLPALTVGSESSLA-----------------LRLVNGGDRCRG 900
Query: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415
RVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G GP++LD+V C+G
Sbjct: 901 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 960
Query: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447
E+ L C H GW HNCGHHEDAG +C+ +
Sbjct: 961 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 992
Score = 270 bits (690), Expect = 3e-72
Identities = 134/261 (51%), Positives = 163/261 (62%), Gaps = 11/261 (4%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RCRGR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 758 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 817
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM-LTSRAP 176
GPI+LD+V C G E+ L C GW HNC H+ED V+C P LT+ P
Sbjct: 818 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLP 877
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
T+ +S ++RLV G + C+GRVE+L+ G WGTVCDD W DA VVCRQLGCG AM
Sbjct: 878 ALTV-GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+A NA FG G+G I+LD+V C G E L +C GW HNCGHHEDAG +C
Sbjct: 937 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC-------- 988
Query: 297 TALPSSATREDWAWQTDPSAT 317
+A ++T DW W + T
Sbjct: 989 SATQINSTTTDW-WHPTTTTT 1008
Score = 132 bits (332), Expect = 9e-31
Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
Query: 185 SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241
S+ ++RLV LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A N
Sbjct: 1128 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1187
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
A+FG G+G I LD+V C G E L C++ GW HNC H EDAG +C+G
Sbjct: 1188 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
Score = 129 bits (325), Expect = 6e-30
Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)
Query: 468 PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
P D LRLVN C GRVE+Y G WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 1127 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1186
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
A+FG G GPI LD+V+C G ES L C + W +HNC+H EDA V+C
Sbjct: 1187 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
Score = 126 bits (317), Expect = 5e-29
Identities = 52/95 (54%), Positives = 64/95 (67%)
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410
G C GRVE+ H G WGTVCDD W +A V CR+ GCG A+ A G +FG G GP+ LD+
Sbjct: 1142 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1201
Query: 411 VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
V C+GTE+ L C + GW HNC H EDAG +C+G
Sbjct: 1202 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1236
Score = 121 bits (304), Expect = 2e-27
Identities = 51/91 (56%), Positives = 63/91 (69%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+ FG G GPI LD+VE
Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
C G E+ L +C +RGW HNC H ED V+C
Sbjct: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 430 bits (1106), Expect = e-120
Identities = 238/599 (39%), Positives = 281/599 (46%), Gaps = 131/599 (21%)
Query: 56 QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115
+ LRL GP C GRLEV HGG WG+VCDD WD+ DA V CRQLGCG AL P FG+
Sbjct: 18 ERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGE 77
Query: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC---------DE------- 159
G GP+ L + CRG E L C RGW H C H ED V+C D+
Sbjct: 78 GAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDG 137
Query: 160 ------FLPTQPPTRKMLTSRAP-------------------------PTTLPNGKSEGS 188
L P T + L + AP P +
Sbjct: 138 APWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQER 197
Query: 189 VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGT 248
+RLV G + C GR+E+ H G WGTVCDD W L DAAV CR+LGCG A+AA A FG G
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257
Query: 249 GHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDW 308
G + +D+V C GGE L C WG NC H EDAG +C G P
Sbjct: 258 GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAP--------------- 302
Query: 309 AWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTV 368
RLRL GP C GR+EV H G WG+V
Sbjct: 303 ----------------------------------RLRLADGPHGCAGRLEVWHGGRWGSV 328
Query: 369 CDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGW 428
CDD WD DA VACRE GCG AL A G FG G GP++LD++ C G E L C W
Sbjct: 329 CDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPW 388
Query: 429 GQHNCGHHEDAGALCAG----------------------------------PEELGLQVQ 454
GQH+C H EDAGA+C G P G+
Sbjct: 389 GQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPP 448
Query: 455 QDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQL 514
P P LRLV G +C GR+E++ QRWGTVCDD+WD+R + V+CR+L
Sbjct: 449 PASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCREL 508
Query: 515 GC-GQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
GC G P FG G GPI LD+V C G E++L C W HNC H+ED V C
Sbjct: 509 GCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTC 567
Score = 380 bits (976), Expect = e-105
Identities = 198/417 (47%), Positives = 238/417 (57%), Gaps = 45/417 (10%)
Query: 48 LQPTPLPFQE-LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALP 106
L T P QE LRLV GP RC GRLEV HGG WG+VCDD WD+ DA V CR+LGCG AL
Sbjct: 187 LLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALA 246
Query: 107 VPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPP 166
P FG G GP+ +D+V C G E AL +C WG NC H ED ++C
Sbjct: 247 APGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVC--------- 297
Query: 167 TRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVV 226
T AP +RL G + C GR+E+ H G WG+VCDD W L DAAV
Sbjct: 298 -----TGPAP-----------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVA 341
Query: 227 CRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286
CR+LGCG A+AA AFFG G+G I+LD++ C G E L C + WG H+C H EDAGA
Sbjct: 342 CRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGA 401
Query: 287 LCAGLG----PPTLTALPSSATREDWAWQTD-------PSATGVGPQPSRETALLTTAAW 335
+C G+ PPT +++T + A + P GV P P+ T L W
Sbjct: 402 VCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVL-----W 456
Query: 336 AAGKKSG--RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC-GPALG 392
G ++G +LRLV GP C GR+EV H WGTVCDD WD D+ V CRE GC GP
Sbjct: 457 EPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQP 516
Query: 393 ATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449
G FG+G GP+ LD+VGC GTEA LSDC WG+HNC H+ED G C GP L
Sbjct: 517 DPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGL 573
Score = 244 bits (623), Expect = 2e-64
Identities = 131/290 (45%), Positives = 160/290 (55%), Gaps = 38/290 (13%)
Query: 54 PFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAF 113
P LRL GP C GRLEV HGG WGSVCDD WD+ DA V CR+LGCG AL P F
Sbjct: 300 PAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFF 359
Query: 114 GQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD----EFLPTQPPT-- 167
G+G GPI+LD++ CRG E AL C +R WG H+C H ED +CD ++P PT
Sbjct: 360 GEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDS 419
Query: 168 ------------RKMLTSRAP-----------PTTL-PNGKSEGS--VRLVGGANLCQGR 201
+TS+AP PT L G GS +RLV G + C GR
Sbjct: 420 NNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGR 479
Query: 202 VEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNA-FFGYGTGHILLDNVHCEG 260
+E+ H WGTVCDD W + D+AVVCR+LGCG A FG+G G I LD+V C G
Sbjct: 480 LEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVG 539
Query: 261 GEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAW 310
E L+ C + WG HNC H+ED G C GPP L ++ + W+W
Sbjct: 540 TEASLSDCPAAPWGKHNCAHNEDVGVTCT--GPPGLDSISDPFS---WSW 584
Score = 136 bits (342), Expect = 6e-32
Identities = 59/103 (57%), Positives = 68/103 (66%)
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
R+RL GP C GR+EV HAG WGTVCDD+WD DA VAC E GCG G H+G G
Sbjct: 771 RVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPG 830
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
GP+ LD++GC G+EA LSDC WG+HNC H ED G C G
Sbjct: 831 TGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873
Score = 129 bits (324), Expect = 7e-30
Identities = 65/137 (47%), Positives = 82/137 (59%), Gaps = 13/137 (9%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
+RL GP+RC GRLEV H G WG+VCDD+WD+ DA V C +LGCG P +G G
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC------DEFLP-TQPPTRK- 169
GPI LD++ C+G EA+LS+C S WG HNC H EDV + C D++ P T PT +
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPPWTWDPTSRE 891
Query: 170 -----MLTSRAPPTTLP 181
T+ P TLP
Sbjct: 892 DLAKGTTTAGVPGHTLP 908
Score = 123 bits (309), Expect = 4e-28
Identities = 56/133 (42%), Positives = 77/133 (57%), Gaps = 8/133 (6%)
Query: 448 ELGLQVQQDGSETTRVPTPRPRDG--------HLRLVNGAHRCEGRVELYLGQRWGTVCD 499
E ++ + E+ + P P P +RL +G +RC GR+E++ RWGTVCD
Sbjct: 739 EPSAEIPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCD 798
Query: 500 DAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDA 559
D WDLR A V C +LGCG+ G+ H+GPG GPI LD++ C+G E++L C W
Sbjct: 799 DNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGK 858
Query: 560 HNCDHSEDASVLC 572
HNCDH ED + C
Sbjct: 859 HNCDHEEDVGLTC 871
Score = 120 bits (300), Expect = 4e-27
Identities = 64/143 (44%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 189 VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGT 248
VRL G N C GR+E+ H+G WGTVCDD+W L DA V C +LGCG +G GT
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831
Query: 249 GHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGP----PTLTALPSSAT 304
G I LD++ C+G E L+ C S WG HNC H ED G C G P T P+S
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPPWTWDPTS-- 889
Query: 305 REDWAWQTDPSATGVGPQPSRET 327
RED A T + P R T
Sbjct: 890 REDLAKGTTTAGVPGHTLPWRTT 912
>gi|44889963 CD163 antigen isoform b [Homo sapiens]
Length = 1121
Score = 338 bits (866), Expect = 1e-92
Identities = 192/541 (35%), Positives = 258/541 (47%), Gaps = 95/541 (17%)
Query: 33 PQALSFLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDA 92
P ++ +LLL +ELRLV G ++C GR+EV WG+VC++ W +
Sbjct: 26 PFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV 85
Query: 93 NVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVH-NCFHYE 151
+V+C QLGC A+ P G G I +D+V CRG E+AL +C GWG H NC H +
Sbjct: 86 SVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQ 145
Query: 152 DVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWG 211
D V C + S +RL G N+C GR+EI G WG
Sbjct: 146 DAGVTCSD------------------------GSNLEMRLTRGGNMCSGRIEIKFQGRWG 181
Query: 212 TVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSL 271
TVCDD++ + A+V+CRQL CG+A++ + ++ FG G+G I D++ C G E L C+
Sbjct: 182 TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
Query: 272 GWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLT 331
GWG HNC H EDAG +C+ +L
Sbjct: 242 GWGKHNCDHAEDAGVICSKGADLSL----------------------------------- 266
Query: 332 TAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL 391
RLV G C GR+EV G WGT+CDD WD DA VAC++ GC A+
Sbjct: 267 -------------RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
Query: 392 GATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGL 451
A G + G G + LD+V C G E + C H WG+H C H+EDAG C+
Sbjct: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS------- 366
Query: 452 QVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511
DGS D LRL G RC G VE+ + + G VCD W L+ A V+C
Sbjct: 367 ----DGS-----------DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411
Query: 512 RQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVL 571
RQLGCG AL + + L C G E++L C + +W CDH E+A +
Sbjct: 412 RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471
Query: 572 C 572
C
Sbjct: 472 C 472
Score = 332 bits (851), Expect = 6e-91
Identities = 193/523 (36%), Positives = 238/523 (45%), Gaps = 83/523 (15%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
ELRL GG SRC G +EV G VCD W + +A+VVCRQLGCG AL +
Sbjct: 372 ELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQ 431
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
L C G E +L +C + WG C HYE+ + C R P
Sbjct: 432 ATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-------------AHREP 478
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
RLVGG C GRVE+ H WG++CD D+ L A+V+CR+L CG +
Sbjct: 479 -------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+ A FG G G I + CEG E L+ C C H D G +C
Sbjct: 526 SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC-------- 577
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
SR T +RLV G PC GR
Sbjct: 578 ---------------------------SRYT---------------EIRLVNGKTPCEGR 595
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VE+ G WG++C+ WD DA V C++ CG AL G FG G G + C GT
Sbjct: 596 VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGS-ETTRVPTPRP------R 469
E + DC G C + A +C+G + L S TR P
Sbjct: 656 EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715
Query: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529
G LRLVNG RC GRVE+Y WGT+CDD+WDL A V+CRQLGCG+A+ A G AHFG
Sbjct: 716 SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775
Query: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G GPI LD +KC G+ES + C W NC H EDA V+C
Sbjct: 776 EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818
Score = 327 bits (839), Expect = 1e-89
Identities = 195/526 (37%), Positives = 241/526 (45%), Gaps = 85/526 (16%)
Query: 55 FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114
+ E+RLV G + C GR+E+ G+WGS+C+ WD+ DA+V+C+QL CG+AL P FG
Sbjct: 580 YTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174
+G G I C G E + +C G C + +V+C Q T S
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS---GNQSQTLSSCNSS 696
Query: 175 APPTTLPNGKSE--------GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVV 226
+ T P E G +RLV G C GRVEI H G WGT+CDD W L DA VV
Sbjct: 697 SLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVV 756
Query: 227 CRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286
CRQLGCG A+ AT +A FG GTG I LD + C G E R+ C S GWG NC H EDAG
Sbjct: 757 CRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGV 816
Query: 287 LCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL 346
+C+ LT S A+RE
Sbjct: 817 ICSEFMSLRLT---SEASRE---------------------------------------- 833
Query: 347 VGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPV 406
C GR+EV + G WGTV V CR+ GC P+
Sbjct: 834 -----ACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
Query: 407 LLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTP 466
+DNV C L C W + E+ C
Sbjct: 889 WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC----------------------- 925
Query: 467 RPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526
D +RL G C GRVE++ G WGTVCDD+WDL A V+C+QLGCG AL A EA
Sbjct: 926 ---DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEA 982
Query: 527 HFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
FG G GPI L+ VKC+G ES+L C RW C H EDA+V C
Sbjct: 983 EFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 326 bits (836), Expect = 3e-89
Identities = 181/517 (35%), Positives = 247/517 (47%), Gaps = 67/517 (12%)
Query: 56 QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115
+E RLVGG C GR+EV HG +WGS+CD D+ + A+V+CR+L CG + + FG+
Sbjct: 476 REPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGE 535
Query: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRA 175
G G I + +C G E+ LS C C H DV V+C +
Sbjct: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT-------------- 581
Query: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235
+RLV G C+GRVE+ G WG++C+ W + DA V+C+QL CG A
Sbjct: 582 ------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295
++ A FG G G I HC G E + C G C + A +C+G T
Sbjct: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
Query: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355
L++ SS+ P+R T +A A +SG+LRLV G G C G
Sbjct: 690 LSSCNSSSLG-----------------PTRPTIPEESAV--ACIESGQLRLVNGGGRCAG 730
Query: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415
RVE+ H G WGT+CDD WD +DA V CR+ GCG A+ ATG HFG G GP+ LD + C G
Sbjct: 731 RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
Query: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRL 475
E+R+ C GWGQ NC H EDAG +C+ E + L++ + S
Sbjct: 791 KESRIWQCHSHGWGQQNCRHKEDAGVICS--EFMSLRLTSEASR---------------- 832
Query: 476 VNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPI 535
C GR+E++ WGTV + GV+CRQLGC + P+
Sbjct: 833 ----EACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
Query: 536 LLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+DNV+C L C W+ SE+ + C
Sbjct: 889 WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
Score = 314 bits (805), Expect = 1e-85
Identities = 183/516 (35%), Positives = 234/516 (45%), Gaps = 96/516 (18%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
E+RL G + C GR+E+ G WG+VCDD++++ A+V+CRQL CG A+ FG+G
Sbjct: 158 EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG 217
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
GPI D++ C G E+AL C +GWG HNC H ED V+C +
Sbjct: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK----------------- 260
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
++ S+RLV G C GR+E+ G WGT+CDD W DAAV C+QLGC A+
Sbjct: 261 -------GADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
A G GHI LD+V C+G EP + C+ WG H C H+EDAG C+ L
Sbjct: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLEL 373
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
RLR GG C G
Sbjct: 374 ----------------------------------------------RLR--GGGSRCAGT 385
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VEV G VCD W +A V CR+ GCG AL + + L C G
Sbjct: 386 VEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGN 445
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476
E L DC + WG C H+E+A C+ E RLV
Sbjct: 446 ETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------------PRLV 481
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
G C GRVE+ G WG++CD + L AA VLCR+L CG ++ G AHFG G G I
Sbjct: 482 GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+ +C G ES L LC C HS D V+C
Sbjct: 542 AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC 577
Score = 159 bits (401), Expect = 9e-39
Identities = 98/268 (36%), Positives = 122/268 (45%), Gaps = 35/268 (13%)
Query: 55 FQELRLVGGPSR--CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLA 112
F LRL SR C GRLEV + G+WG+V VVCRQLGC + P +
Sbjct: 821 FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKI-NPAS 879
Query: 113 FGQGRG-PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKML 171
+ P+ +DNV+C L +C S W E+ + CD
Sbjct: 880 LDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN------------ 927
Query: 172 TSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
+RL G C GRVEI H G WGTVCDD W L DA VVC+QLG
Sbjct: 928 ----------------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLG 971
Query: 232 CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGL 291
CG A+ A A FG GTG I L+ V C+G E L C + WG CGH EDA C +
Sbjct: 972 CGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDI 1031
Query: 292 GPPTLTALPSSATREDWAWQTDPSATGV 319
++ P AT + Q+ A G+
Sbjct: 1032 ---SVQKTPQKATTGRSSRQSSFIAVGI 1056
>gi|44662834 CD163 antigen isoform a [Homo sapiens]
Length = 1156
Score = 338 bits (866), Expect = 1e-92
Identities = 192/541 (35%), Positives = 258/541 (47%), Gaps = 95/541 (17%)
Query: 33 PQALSFLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDA 92
P ++ +LLL +ELRLV G ++C GR+EV WG+VC++ W +
Sbjct: 26 PFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAV 85
Query: 93 NVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVH-NCFHYE 151
+V+C QLGC A+ P G G I +D+V CRG E+AL +C GWG H NC H +
Sbjct: 86 SVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQ 145
Query: 152 DVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWG 211
D V C + S +RL G N+C GR+EI G WG
Sbjct: 146 DAGVTCSD------------------------GSNLEMRLTRGGNMCSGRIEIKFQGRWG 181
Query: 212 TVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSL 271
TVCDD++ + A+V+CRQL CG+A++ + ++ FG G+G I D++ C G E L C+
Sbjct: 182 TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241
Query: 272 GWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLT 331
GWG HNC H EDAG +C+ +L
Sbjct: 242 GWGKHNCDHAEDAGVICSKGADLSL----------------------------------- 266
Query: 332 TAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL 391
RLV G C GR+EV G WGT+CDD WD DA VAC++ GC A+
Sbjct: 267 -------------RLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
Query: 392 GATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGL 451
A G + G G + LD+V C G E + C H WG+H C H+EDAG C+
Sbjct: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS------- 366
Query: 452 QVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511
DGS D LRL G RC G VE+ + + G VCD W L+ A V+C
Sbjct: 367 ----DGS-----------DLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVC 411
Query: 512 RQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVL 571
RQLGCG AL + + L C G E++L C + +W CDH E+A +
Sbjct: 412 RQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKIT 471
Query: 572 C 572
C
Sbjct: 472 C 472
Score = 332 bits (851), Expect = 6e-91
Identities = 193/523 (36%), Positives = 238/523 (45%), Gaps = 83/523 (15%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
ELRL GG SRC G +EV G VCD W + +A+VVCRQLGCG AL +
Sbjct: 372 ELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQ 431
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
L C G E +L +C + WG C HYE+ + C R P
Sbjct: 432 ATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-------------AHREP 478
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
RLVGG C GRVE+ H WG++CD D+ L A+V+CR+L CG +
Sbjct: 479 -------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+ A FG G G I + CEG E L+ C C H D G +C
Sbjct: 526 SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC-------- 577
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
SR T +RLV G PC GR
Sbjct: 578 ---------------------------SRYT---------------EIRLVNGKTPCEGR 595
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VE+ G WG++C+ WD DA V C++ CG AL G FG G G + C GT
Sbjct: 596 VELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGT 655
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGS-ETTRVPTPRP------R 469
E + DC G C + A +C+G + L S TR P
Sbjct: 656 EQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIE 715
Query: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529
G LRLVNG RC GRVE+Y WGT+CDD+WDL A V+CRQLGCG+A+ A G AHFG
Sbjct: 716 SGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFG 775
Query: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G GPI LD +KC G+ES + C W NC H EDA V+C
Sbjct: 776 EGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC 818
Score = 327 bits (839), Expect = 1e-89
Identities = 195/526 (37%), Positives = 241/526 (45%), Gaps = 85/526 (16%)
Query: 55 FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114
+ E+RLV G + C GR+E+ G+WGS+C+ WD+ DA+V+C+QL CG+AL P FG
Sbjct: 580 YTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174
+G G I C G E + +C G C + +V+C Q T S
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICS---GNQSQTLSSCNSS 696
Query: 175 APPTTLPNGKSE--------GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVV 226
+ T P E G +RLV G C GRVEI H G WGT+CDD W L DA VV
Sbjct: 697 SLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVV 756
Query: 227 CRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286
CRQLGCG A+ AT +A FG GTG I LD + C G E R+ C S GWG NC H EDAG
Sbjct: 757 CRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGV 816
Query: 287 LCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL 346
+C+ LT S A+RE
Sbjct: 817 ICSEFMSLRLT---SEASRE---------------------------------------- 833
Query: 347 VGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPV 406
C GR+EV + G WGTV V CR+ GC P+
Sbjct: 834 -----ACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
Query: 407 LLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTP 466
+DNV C L C W + E+ C
Sbjct: 889 WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC----------------------- 925
Query: 467 RPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526
D +RL G C GRVE++ G WGTVCDD+WDL A V+C+QLGCG AL A EA
Sbjct: 926 ---DNKIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEA 982
Query: 527 HFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
FG G GPI L+ VKC+G ES+L C RW C H EDA+V C
Sbjct: 983 EFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 326 bits (836), Expect = 3e-89
Identities = 181/517 (35%), Positives = 247/517 (47%), Gaps = 67/517 (12%)
Query: 56 QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115
+E RLVGG C GR+EV HG +WGS+CD D+ + A+V+CR+L CG + + FG+
Sbjct: 476 REPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGE 535
Query: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRA 175
G G I + +C G E+ LS C C H DV V+C +
Sbjct: 536 GNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYT-------------- 581
Query: 176 PPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAA 235
+RLV G C+GRVE+ G WG++C+ W + DA V+C+QL CG A
Sbjct: 582 ------------EIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 236 MAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPT 295
++ A FG G G I HC G E + C G C + A +C+G T
Sbjct: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
Query: 296 LTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRG 355
L++ SS+ P+R T +A A +SG+LRLV G G C G
Sbjct: 690 LSSCNSSSLG-----------------PTRPTIPEESAV--ACIESGQLRLVNGGGRCAG 730
Query: 356 RVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAG 415
RVE+ H G WGT+CDD WD +DA V CR+ GCG A+ ATG HFG G GP+ LD + C G
Sbjct: 731 RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790
Query: 416 TEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRL 475
E+R+ C GWGQ NC H EDAG +C+ E + L++ + S
Sbjct: 791 KESRIWQCHSHGWGQQNCRHKEDAGVICS--EFMSLRLTSEASR---------------- 832
Query: 476 VNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPI 535
C GR+E++ WGTV + GV+CRQLGC + P+
Sbjct: 833 ----EACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888
Query: 536 LLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+DNV+C L C W+ SE+ + C
Sbjct: 889 WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITC 925
Score = 314 bits (805), Expect = 1e-85
Identities = 183/516 (35%), Positives = 234/516 (45%), Gaps = 96/516 (18%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
E+RL G + C GR+E+ G WG+VCDD++++ A+V+CRQL CG A+ FG+G
Sbjct: 158 EMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG 217
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
GPI D++ C G E+AL C +GWG HNC H ED V+C +
Sbjct: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSK----------------- 260
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
++ S+RLV G C GR+E+ G WGT+CDD W DAAV C+QLGC A+
Sbjct: 261 -------GADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAV 313
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
A G GHI LD+V C+G EP + C+ WG H C H+EDAG C+ L
Sbjct: 314 TAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCSDGSDLEL 373
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
RLR GG C G
Sbjct: 374 ----------------------------------------------RLR--GGGSRCAGT 385
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VEV G VCD W +A V CR+ GCG AL + + L C G
Sbjct: 386 VEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGN 445
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476
E L DC + WG C H+E+A C+ E RLV
Sbjct: 446 ETSLWDCKNWQWGGLTCDHYEEAKITCSAHRE------------------------PRLV 481
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
G C GRVE+ G WG++CD + L AA VLCR+L CG ++ G AHFG G G I
Sbjct: 482 GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+ +C G ES L LC C HS D V+C
Sbjct: 542 AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVC 577
Score = 159 bits (401), Expect = 9e-39
Identities = 98/268 (36%), Positives = 122/268 (45%), Gaps = 35/268 (13%)
Query: 55 FQELRLVGGPSR--CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLA 112
F LRL SR C GRLEV + G+WG+V VVCRQLGC + P +
Sbjct: 821 FMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKI-NPAS 879
Query: 113 FGQGRG-PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKML 171
+ P+ +DNV+C L +C S W E+ + CD
Sbjct: 880 LDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN------------ 927
Query: 172 TSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
+RL G C GRVEI H G WGTVCDD W L DA VVC+QLG
Sbjct: 928 ----------------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLG 971
Query: 232 CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGL 291
CG A+ A A FG GTG I L+ V C+G E L C + WG CGH EDA C +
Sbjct: 972 CGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDI 1031
Query: 292 GPPTLTALPSSATREDWAWQTDPSATGV 319
++ P AT + Q+ A G+
Sbjct: 1032 ---SVQKTPQKATTGRSSRQSSFIAVGI 1056
>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
sapiens]
Length = 1453
Score = 337 bits (865), Expect = 1e-92
Identities = 201/576 (34%), Positives = 262/576 (45%), Gaps = 109/576 (18%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G + C GR+EV WG++CDD W++ A VVCRQLGC + +
Sbjct: 155 LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVL 214
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
PI LD++ C+G E AL C RGWG H+C H EDV + C +
Sbjct: 215 RPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYD------------------ 256
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
S+ +RLVGG N C GRVE+ G WGTVC W A VVC+QLGCG A+
Sbjct: 257 ------SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALH 310
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGAL---------- 287
G+ + LD V C G E L C+ G +C H D +
Sbjct: 311 FAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELR 370
Query: 288 ------------------------------------CAGLGPP-----TLTALPSSATRE 306
C LG P + A PS+ R+
Sbjct: 371 LADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARD 430
Query: 307 DWAWQTDPSATG--------VGPQPSRETALLTTAAWA--AGKKSGRLRLVGGPGPCRGR 356
W S TG ++ T + A + K LRLVG PC GR
Sbjct: 431 IWI--NSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVGAHSPCYGR 488
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
+EV + G WGTVC D W +A V C++ GCG + G+ +F GP+ LD+V C G
Sbjct: 489 LEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGN 548
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476
E+ + DC H GWG+HNC H ED C+G G LRLV
Sbjct: 549 ESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWG----------------------LRLV 586
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
G++RC GR+E+Y RWGTVCDD W+ +AA V+C QL C ++ G + G G I
Sbjct: 587 GGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW 646
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
LD+V C G+ES L C + W ++C HSED V+C
Sbjct: 647 LDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC 682
Score = 311 bits (797), Expect = 1e-84
Identities = 188/519 (36%), Positives = 242/519 (46%), Gaps = 100/519 (19%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
ELRLV G C G +EV G WG+VCDD W+ + VVC+QLGC + + R FGQ
Sbjct: 47 ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFR---FGQA 103
Query: 117 ---RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTS 173
G I LD+V C G E+AL EC R WG HNC+H EDV V C
Sbjct: 104 VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---------------- 147
Query: 174 RAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCG 233
G++ +RLV G N C GRVE+ WGT+CDD W L AAVVCRQLGC
Sbjct: 148 --------YGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCP 199
Query: 234 AAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGP 293
++ ++ I LD++ C+G E L C+ GWG H+C H+ED
Sbjct: 200 SSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV--------- 250
Query: 294 PTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPC 353
TLT SS LRLVGG C
Sbjct: 251 -TLTCYDSSDL--------------------------------------ELRLVGGTNRC 271
Query: 354 RGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGC 413
GRVE+ G WGTVC W+ A A V C++ GCG AL GL H G V LD V C
Sbjct: 272 MGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSC 331
Query: 414 AGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHL 473
+G E+ L DC H G +C H D +C+ DG+ D L
Sbjct: 332 SGNESFLWDCRHSGTVNFDCLHQNDVSVICS-----------DGA-----------DLEL 369
Query: 474 RLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRG 533
RL +G++ C GRVE+ + ++W T+CD W A V+C+QLGC ++ A
Sbjct: 370 RLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEAR 429
Query: 534 PILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
I ++++ C G ESAL C++ C DA V+C
Sbjct: 430 DIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVIC 468
Score = 310 bits (794), Expect = 2e-84
Identities = 178/516 (34%), Positives = 233/516 (45%), Gaps = 96/516 (18%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
+LRLVG S C GRLEV + G WG+VC D W +A VVC+QLGCG + V F +
Sbjct: 475 DLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEA 534
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
GPI LD+V C G E+ + +C GWG HNC H EDV V C
Sbjct: 535 SGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTC------------------- 575
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
+G + +RLVGG+N C GR+E+ G WGTVCDD W AAVVC QL C +++
Sbjct: 576 -----SGDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSI 630
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
G G I LD+V C+G E L +C++ GWG ++C H ED G +C
Sbjct: 631 IGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC-------- 682
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
+ LRLVGG C G+
Sbjct: 683 ----------------------------------------SDASDMELRLVGGSSRCAGK 702
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VEV G G +C + W A V CR+ CG A+ + HF +L+ N GC G
Sbjct: 703 VEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGG 762
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476
EA L DC W Q C + +A +C+ + RLV
Sbjct: 763 EASLWDCIRWEWKQTACHLNMEASLICSAHRQ------------------------PRLV 798
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
C GRVE+ W +VCD + L AA VLCR+L CG A++ HFG G G
Sbjct: 799 GADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTW 858
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+ +C G E+ L LC ++ C HS + V+C
Sbjct: 859 AEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVC 894
Score = 306 bits (785), Expect = 3e-83
Identities = 187/525 (35%), Positives = 245/525 (46%), Gaps = 83/525 (15%)
Query: 55 FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114
+ ++RLV G S+C G++E+ G WGS+CD WD DA V+CRQL CG AL G
Sbjct: 897 YTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174
+ + C G E+ L C G C H V+V+C L TQP +
Sbjct: 957 ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSL-TQPLFPCLANVS 1015
Query: 175 AP-PTTLPNGKS-----EGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCR 228
P + +P G + + +RLV G + C GRVEI H G WGT+CDD W L DA VVC+
Sbjct: 1016 DPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQ 1075
Query: 229 QLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288
+LGCG A AT +A FG G+G I LD+++C G E L C S GWG H+C H EDAG +C
Sbjct: 1076 KLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135
Query: 289 AGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVG 348
S TAL RL
Sbjct: 1136 -----------------------------------SEFTAL-------------RLYSET 1147
Query: 349 GPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFG-YGRGPVL 407
C GR+EV + G WG+V + A A + CR+ GCG G L G G +
Sbjct: 1148 ETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGEN-GVVSLAPLSKTGSGFMW 1206
Query: 408 LDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR 467
+D++ C T + C W + E+ C
Sbjct: 1207 VDDIQCPKTHISIWQCLSAPWERRISSPAEETWITC------------------------ 1242
Query: 468 PRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAH 527
+ +R+ G C GRVE++ WGTVCDD+WDL A V+C+QLGCG ALAA +A
Sbjct: 1243 --EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDAS 1300
Query: 528 FGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
FG G G I LD+++C+G ES L C W +C H EDA V C
Sbjct: 1301 FGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRC 1345
Score = 301 bits (770), Expect = 1e-81
Identities = 174/516 (33%), Positives = 235/516 (45%), Gaps = 94/516 (18%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
ELRL G + C GR+EV W ++CD +W A VVC+QLGC ++ R
Sbjct: 368 ELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNE 427
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
I ++++ C G E+AL +C G CF D V+C +
Sbjct: 428 ARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSD----------------- 470
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
K++ +RLVG + C GR+E+ + G WGTVC D W +AAVVC+QLGCG M
Sbjct: 471 -------KADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPM 523
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+F +G I LD+V C G E + C+ GWG HNC H ED C+G
Sbjct: 524 HVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG------ 577
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
A W LRLVGG C GR
Sbjct: 578 -----------------------------------DATWG-------LRLVGGSNRCSGR 595
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
+EV G WGTVCDD W+ A V C + C ++ GLG+ G G + LD+V C G
Sbjct: 596 LEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGD 655
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476
E+ L C + GWG ++C H ED G +C+ D S D LRLV
Sbjct: 656 ESDLWSCRNSGWGNNDCSHSEDVGVICS-----------DAS-----------DMELRLV 693
Query: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536
G+ RC G+VE+ + G +C + W + A V+CRQL CG A+ E HF IL
Sbjct: 694 GGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHIL 753
Query: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
+ N C G E++L C W C + +AS++C
Sbjct: 754 MSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLIC 789
Score = 290 bits (743), Expect = 2e-78
Identities = 184/528 (34%), Positives = 235/528 (44%), Gaps = 93/528 (17%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
ELRLVGG SRC G++EV G+ G +C + W + A VVCRQL CG A+ V R F +
Sbjct: 689 ELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTER 748
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176
IL+ N C G EA+L +C W C + +++C R P
Sbjct: 749 TLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICS-------------AHRQP 795
Query: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236
RLVG C GRVE+ H+ W +VCD D+ L A V+CR+L CG A+
Sbjct: 796 -------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842
Query: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296
+ + FG G G + CEG E LA C + C H + G +C
Sbjct: 843 SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVC-------- 894
Query: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356
SR T +RLV G C G+
Sbjct: 895 ---------------------------SRYT---------------DVRLVNGKSQCDGQ 912
Query: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416
VE+ G WG++CD WD DARV CR+ CG AL TG + G V C G
Sbjct: 913 VEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGN 972
Query: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGP------------EELGLQVQQDGSETTRVP 464
E+ L +C G C H +C G + L +GS +
Sbjct: 973 ESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICL- 1031
Query: 465 TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524
D LRLV+G RC GRVE+Y WGT+CDD WDL A V+C++LGCG A A
Sbjct: 1032 ----EDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATV 1087
Query: 525 EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
AHFG G GPI LD++ C G ES L C W H+C H EDA V+C
Sbjct: 1088 SAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135
Score = 290 bits (742), Expect = 2e-78
Identities = 173/516 (33%), Positives = 235/516 (45%), Gaps = 69/516 (13%)
Query: 59 RLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRG 118
RLVG C GR+EV H +W SVCD D+ + ANV+CR+L CG A+ + FG+G G
Sbjct: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
Query: 119 PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPT 178
+ +C G E L+ C C H +V V+C +
Sbjct: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYT----------------- 898
Query: 179 TLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAA 238
VRLV G + C G+VEI G WG++CD W DA V+CRQL CG A++
Sbjct: 899 ---------DVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALST 949
Query: 239 TTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG-LGPPTLT 297
T + G + + HC G E L CQ G C H +C G L P
Sbjct: 950 TGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFP 1009
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
L + + DP + V P+ S L + RLRLV G C GRV
Sbjct: 1010 CLANVS---------DPYLSAV-PEGSALICL----------EDKRLRLVDGDSRCAGRV 1049
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
E+ H G WGT+CDD WD +DA V C++ GCG A AT HFG G GP+ LD++ C G E
Sbjct: 1050 EIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGME 1109
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477
+ L C GWGQH+C H EDAG +C+ L L SET
Sbjct: 1110 SHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLY-----SETE---------------- 1148
Query: 478 GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537
C GR+E++ WG+V AG++CRQLGCG+ G G + +
Sbjct: 1149 -TESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWV 1207
Query: 538 DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQ 573
D+++C ++ C W+ +E+ + C+
Sbjct: 1208 DDIQCPKTHISIWQCLSAPWERRISSPAEETWITCE 1243
Score = 276 bits (705), Expect = 5e-74
Identities = 173/518 (33%), Positives = 226/518 (43%), Gaps = 98/518 (18%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLVGG +RC GRLEV G WG+VCDD W+ A VVC QL C ++ G
Sbjct: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGY 642
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
G I LD+V C G E+ L C + GWG ++C H EDV V+C +
Sbjct: 643 GKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSD------------------ 684
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237
S+ +RLVGG++ C G+VE+ G G +C + WG+ A VVCRQL CG+A+
Sbjct: 685 ------ASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIR 738
Query: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297
+ F T HIL+ N C GGE L C W C + +A +C+ P
Sbjct: 739 VSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP--- 795
Query: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357
RLVG PC GRV
Sbjct: 796 -----------------------------------------------RLVGADMPCSGRV 808
Query: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
EV HA W +VCD D+ A V CRE CG A+ + HFG G G + C G+E
Sbjct: 809 EVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSE 868
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477
L+ C + + C H + G +C+ R +RLVN
Sbjct: 869 THLALCPIVQHPEDTCIHSREVGVVCS------------------------RYTDVRLVN 904
Query: 478 GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537
G +C+G+VE+ + WG++CD WD A VLCRQL CG AL+ G + G +
Sbjct: 905 GKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWG 964
Query: 538 DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
C G ES L C A C H SV+C S
Sbjct: 965 HRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGS 1002
Score = 266 bits (680), Expect = 4e-71
Identities = 154/425 (36%), Positives = 201/425 (47%), Gaps = 82/425 (19%)
Query: 25 GSAAPPFLPQALS----FLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWG 80
GS P P + +L +P SAL L + LRLV G SRC GR+E+ H G WG
Sbjct: 1001 GSLTQPLFPCLANVSDPYLSAVPEGSAL--ICLEDKRLRLVDGDSRCAGRVEIYHDGFWG 1058
Query: 81 SVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSR 140
++CDD WD+ DA+VVC++LGCG+A FG+G GPI LD++ C G E+ L +C SR
Sbjct: 1059 TICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSR 1118
Query: 141 GWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQG 200
GWG H+C H ED V+C EF T L S + C G
Sbjct: 1119 GWGQHDCRHKEDAGVICSEF------TALRLYSETETES------------------CAG 1154
Query: 201 RVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEG 260
R+E+ ++G WG+V + A +VCRQLGCG + G+G + +D++ C
Sbjct: 1155 RLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPK 1214
Query: 261 GEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVG 320
+ C S W SS E W D
Sbjct: 1215 THISIWQCLSAPW-----------------------ERRISSPAEETWITCED------- 1244
Query: 321 PQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARV 380
R+R+ GG C GRVE+ HAG WGTVCDD WD A+A V
Sbjct: 1245 ----------------------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEV 1282
Query: 381 ACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAG 440
C++ GCG AL A FG G G + LD++ C G E+ L DC WGQ +CGH EDAG
Sbjct: 1283 VCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAG 1342
Query: 441 ALCAG 445
C+G
Sbjct: 1343 VRCSG 1347
Score = 196 bits (497), Expect = 6e-50
Identities = 96/232 (41%), Positives = 122/232 (52%), Gaps = 22/232 (9%)
Query: 344 LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGR 403
LRLV G GPC G VEV G WGTVCDD W+ + V C++ GC + G
Sbjct: 48 LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRH 107
Query: 404 GPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRV 463
G + LD+V C G E+ L +C H WG HNC H ED G C G LG
Sbjct: 108 GKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLG------------- 154
Query: 464 PTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAP 523
LRLV+G + C GRVE+ +RWGT+CDD W+L A V+CRQLGC + +
Sbjct: 155 ---------LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISS 205
Query: 524 GEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
G + PI LD++ C+G E AL C H W H+C H+ED ++ C S
Sbjct: 206 GVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS 257
Score = 164 bits (416), Expect = 2e-40
Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 28/232 (12%)
Query: 67 CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126
C GRLEV + G+WGSV + A +VCRQLGCG V G G + +D+++
Sbjct: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
Query: 127 CRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSE 186
C ++ +C S W E+ + C++
Sbjct: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITCED--------------------------- 1244
Query: 187 GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY 246
+R+ GG C GRVEI H+G WGTVCDD W L +A VVC+QLGCG+A+AA +A FG
Sbjct: 1245 -RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQ 1303
Query: 247 GTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTA 298
GTG I LD++ C+G E L C + WG +CGH EDAG C+G +L A
Sbjct: 1304 GTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNA 1355
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/103 (47%), Positives = 58/103 (56%)
Query: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529
D LRLVNG C G VE+ +WGTVCDD W+ A+ V+C+QLGC + A
Sbjct: 45 DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAV 104
Query: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G I LD+V C G ESAL C H W +HNC H ED V C
Sbjct: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 328 bits (842), Expect = 6e-90
Identities = 192/518 (37%), Positives = 245/518 (47%), Gaps = 91/518 (17%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQL---GCGLALPVPRPLAFG 114
+RL GG + G +EV G WG+VC WD DA+V+C QL G G+A P G
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS---G 226
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174
G PI NV CRG E + C W C AV C
Sbjct: 227 LGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTC----------------- 269
Query: 175 APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGA 234
+ +G + +RL GG+++ +GRVE+ H+G WGTVCDD W DA V+CRQLG
Sbjct: 270 ----SFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325
Query: 235 AMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPP 294
A A+FG G+G ++LD V C G E + C WG HNCGH EDAG C L
Sbjct: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382
Query: 295 TLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCR 354
TD G +RL GG G
Sbjct: 383 -----------------TD----------------------------GVIRLAGGKGSHE 397
Query: 355 GRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCA 414
GR+EV + G WGTVCDD W + V CR+ G A+ HF GP+ LD+V C+
Sbjct: 398 GRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASA-NHFEESTGPIWLDDVSCS 456
Query: 415 GTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLR 474
G E R C WG+H+C H ED C G E R+ P +R
Sbjct: 457 GKETRFLQCSRRQWGRHDCSHREDVSIAC-----------YPGGEGHRLSLGFP----VR 501
Query: 475 LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534
L++G ++ EGRVE+++ +WGT+CDD W + A V+CRQLG A A+FG G+GP
Sbjct: 502 LMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGP 561
Query: 535 ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
I +DNVKC G E +L C HNC HSEDA V+C
Sbjct: 562 IHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
Score = 266 bits (681), Expect = 3e-71
Identities = 148/392 (37%), Positives = 182/392 (46%), Gaps = 72/392 (18%)
Query: 55 FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114
F +RL GG S GR+E+ H G WG+VCDD WD DA V+CRQLG FG
Sbjct: 277 FPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFG 336
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174
+G GP++LD V C G E ++ +C WG HNC H ED V C
Sbjct: 337 EGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL-------------- 382
Query: 175 APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGA 234
++G +RL GG +GR+E+ + G WGTVCDD W + VVCRQLG
Sbjct: 383 ----------TDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKY 432
Query: 235 AMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC--AGLG 292
A+ N F TG I LD+V C G E R C WG H+C H ED C G G
Sbjct: 433 GKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEG 491
Query: 293 PPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGP 352
P +RL+ G
Sbjct: 492 HRLSLGFP-------------------------------------------VRLMDGENK 508
Query: 353 CRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC-GPALGATGLGHFGYGRGPVLLDNV 411
GRVEV G WGT+CDD W DA V CR+ G GPA T + +FG G+GP+ +DNV
Sbjct: 509 KEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARART-MAYFGEGKGPIHVDNV 567
Query: 412 GCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443
C G E L+DC G+HNC H EDAG +C
Sbjct: 568 KCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599
Score = 253 bits (647), Expect = 3e-67
Identities = 148/388 (38%), Positives = 177/388 (45%), Gaps = 68/388 (17%)
Query: 187 GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY 246
GSVRL GG N +G VE+ SG+WGTVC W DA+V+C QL G A F G
Sbjct: 168 GSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGL 227
Query: 247 GTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATRE 306
G I NV C G E + C+ W
Sbjct: 228 GLIPIYWSNVRCRGDEENILLCEKDIW--------------------------------- 254
Query: 307 DWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWG 366
GV PQ + A T +++ G +RL GG GRVE+ HAG WG
Sbjct: 255 ---------QGGVCPQ---KMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWG 302
Query: 367 TVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHL 426
TVCDD WD ADA V CR+ G A +FG G GPV+LD V C G E + C
Sbjct: 303 TVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKS 362
Query: 427 GWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRV 486
WG+HNCGH EDAG C TP DG +RL G EGR+
Sbjct: 363 SWGEHNCGHKEDAGVSC---------------------TPL-TDGVIRLAGGKGSHEGRL 400
Query: 487 ELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEE 546
E+Y +WGTVCDD W V+CRQLG A HF GPI LD+V C G+E
Sbjct: 401 EVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKE 459
Query: 547 SALLLCSHIRWDAHNCDHSEDASVLCQP 574
+ L CS +W H+C H ED S+ C P
Sbjct: 460 TRFLQCSRRQWGRHDCSHREDVSIACYP 487
Score = 188 bits (478), Expect = 1e-47
Identities = 104/247 (42%), Positives = 126/247 (51%), Gaps = 28/247 (11%)
Query: 51 TPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRP 110
TPL +RL GG GRLEV + G WG+VCDD W ++ VVCRQLG
Sbjct: 380 TPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN 439
Query: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM 170
F + GPI LD+V C G+E +C R WG H+C H EDV++ C
Sbjct: 440 -HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC------------- 485
Query: 171 LTSRAPPTTLPNGKSEG-----SVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAV 225
P G+ VRL+ G N +GRVE+ +G WGT+CDD W DAAV
Sbjct: 486 ---------YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAV 536
Query: 226 VCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAG 285
+CRQLG A T A+FG G G I +DNV C G E LA C G HNC H EDAG
Sbjct: 537 ICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAG 596
Query: 286 ALCAGLG 292
+C G
Sbjct: 597 VICDYFG 603
Score = 154 bits (390), Expect = 2e-37
Identities = 90/235 (38%), Positives = 112/235 (47%), Gaps = 19/235 (8%)
Query: 340 KSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHF 399
+ G +RL GG G VEV +G WGTVC WD +DA V C + G A
Sbjct: 166 RHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS 225
Query: 400 GYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSE 459
G G P+ NV C G E + C W G +C P+++ V S
Sbjct: 226 GLGLIPIYWSNVRCRGDEENILLCEKDIW----------QGGVC--PQKMAAAVTCSFSH 273
Query: 460 TTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQA 519
P +RL G+ EGRVELY +WGTVCDD WD A V+CRQLG
Sbjct: 274 GPTFPI-------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326
Query: 520 LAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQP 574
A +A+FG G GP++LD V+C G E ++ C W HNC H EDA V C P
Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP 381
>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
Length = 343
Score = 267 bits (683), Expect = 2e-71
Identities = 133/260 (51%), Positives = 163/260 (62%), Gaps = 17/260 (6%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
LRLV G RC+GR+EV++ GSWG+VCDD WD DANVVCRQLGCG A+ P FGQG
Sbjct: 18 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQP------PTRKML 171
GPI+LD+V C G E+ L C GW HNC H ED V+C P P P+R +
Sbjct: 78 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137
Query: 172 TSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
+ P ++L ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLG
Sbjct: 138 SPIGPESSL-------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 190
Query: 232 CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG- 290
CG A +A NA FG G+G I+LD+V C G E L +C + GW HNCGHHEDAG +C+G
Sbjct: 191 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250
Query: 291 ---LGPPTLTALPSSATRED 307
GP +P A +D
Sbjct: 251 WAVAGPRRPQEMPGLARAQD 270
Score = 264 bits (674), Expect = 2e-70
Identities = 132/262 (50%), Positives = 159/262 (60%), Gaps = 25/262 (9%)
Query: 184 KSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAF 243
+S ++RLV G + CQGRVE+L+ G WGTVCDD W DA VVCRQLGCG AM A NA
Sbjct: 13 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 72
Query: 244 FGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSA 303
FG G+G I+LD+V C G E L +C GW HNCGH EDAG +C+G GPP P S
Sbjct: 73 FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSG-GPPRTPIRPRS- 130
Query: 304 TREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAG 363
W + + +GP+ S LRLV G C+GRVEVL+ G
Sbjct: 131 ------WPSRFLCSPIGPESSL-----------------ALRLVNGGDRCQGRVEVLYRG 167
Query: 364 GWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDC 423
WGTVCDD WD DA V CR+ GCG A A G FG G GP++LD+V C+G E+ L C
Sbjct: 168 SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSC 227
Query: 424 FHLGWGQHNCGHHEDAGALCAG 445
+ GW HNCGHHEDAG +C+G
Sbjct: 228 PNNGWLSHNCGHHEDAGVICSG 249
Score = 258 bits (660), Expect = 8e-69
Identities = 124/233 (53%), Positives = 149/233 (63%), Gaps = 1/233 (0%)
Query: 344 LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGR 403
LRLV G C+GRVEVL+ G WGTVCDD WD DA V CR+ GCG A+ A G FG G
Sbjct: 18 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77
Query: 404 GPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG-PEELGLQVQQDGSETTR 462
GP++LD+V C+G E+ L C H GW HNCGH EDAG +C+G P ++ + S
Sbjct: 78 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137
Query: 463 VPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAA 522
P LRLVNG RC+GRVE+ WGTVCDD+WD A V+CRQLGCG A +A
Sbjct: 138 SPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 197
Query: 523 PGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575
PG A FG G GPI+LD+V+C G ES L C + W +HNC H EDA V+C S
Sbjct: 198 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 257 bits (656), Expect = 2e-68
Identities = 148/394 (37%), Positives = 188/394 (47%), Gaps = 74/394 (18%)
Query: 185 SEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFF 244
S VRLVGG + C+GRVE+ G WGTVCDD W + D AV+CR+LGCGAA + +
Sbjct: 20 SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79
Query: 245 ---GYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPS 301
+L+ +V C G E LA C+ V++C H EDAGA C P
Sbjct: 80 EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCEN---------PE 128
Query: 302 SATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLH 361
S+ P GV RL GPG C+GRVEV H
Sbjct: 129 SSF--------SPVPEGV-------------------------RLADGPGHCKGRVEVKH 155
Query: 362 AGGWGTVCDDDWDFADARVACREAGCGPA-LGATGLGHFGYGRGPVLLDNVGCAGTEARL 420
W TVC W A+V CR+ GCG A L YGR P+ L + C+G EA L
Sbjct: 156 QNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATL 215
Query: 421 SDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAH 480
DC WG++ C H ED C P +L RLV G +
Sbjct: 216 QDCPSGPWGKNTCNHDEDTWVECEDPFDL------------------------RLVGGDN 251
Query: 481 RCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAH--FGPGRGPILLD 538
C GR+E+ WG+VCDD W + V+C+QLGCG++L+ +GPG G I LD
Sbjct: 252 LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLD 311
Query: 539 NVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
NV+C GEE +L C H W H+C H ED +V+C
Sbjct: 312 NVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVIC 345
Score = 241 bits (616), Expect = 1e-63
Identities = 147/417 (35%), Positives = 189/417 (45%), Gaps = 77/417 (18%)
Query: 36 LSFLLLLPLASALQPTPLPFQE-LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANV 94
++ L L LA +P L +RLVGG RC GR+EV G WG+VCDD WD+ D V
Sbjct: 1 MALLFSLILAICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAV 60
Query: 95 VCRQLGCGLALPVPRPLAF---GQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYE 151
+CR+LGCG A P + + + +L+ +V C G E L++C V++C H E
Sbjct: 61 LCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDE 118
Query: 152 DVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWG 211
D C+ + P +P G VRL G C+GRVE+ H W
Sbjct: 119 DAGASCENPESSFSP-------------VPEG-----VRLADGPGHCKGRVEVKHQNQWY 160
Query: 212 TVCDDDWGLPDAAVVCRQLGCGAAMAATTNA-FFGYGTGHILLDNVHCEGGEPRLAACQS 270
TVC W L A VVCRQLGCG A+ YG I L + C G E L C S
Sbjct: 161 TVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPS 220
Query: 271 LGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALL 330
WG + C H ED W DP
Sbjct: 221 GPWGKNTCNHDEDT-----------------------WVECEDPF--------------- 242
Query: 331 TTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPA 390
LRLVGG C GR+EVLH G WG+VCDD+W + +V C++ GCG +
Sbjct: 243 ------------DLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKS 290
Query: 391 LGATGLGH--FGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
L + +G G G + LDNV C+G E L C H WG H+C H ED +C+G
Sbjct: 291 LSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347
Score = 165 bits (417), Expect = 1e-40
Identities = 97/234 (41%), Positives = 121/234 (51%), Gaps = 22/234 (9%)
Query: 344 LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGA-TGLGHF--G 400
+RLVGG C GRVEV G WGTVCDD WD D V CRE GCG A G +G+ +
Sbjct: 24 VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83
Query: 401 YGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSET 460
VL+ +V C GTE L+ C ++C H EDAGA C PE S
Sbjct: 84 EKEQKVLIQSVSCTGTEDTLAQCEQ--EEVYDCSHDEDAGASCENPE----------SSF 131
Query: 461 TRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQAL 520
+ VP +RL +G C+GRVE+ +W TVC W LRAA V+CRQLGCG+A+
Sbjct: 132 SPVPE------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAV 185
Query: 521 AAPGEAH-FGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQ 573
+ GR PI L + C G E+ L C W + C+H ED V C+
Sbjct: 186 LTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECE 239
>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
Length = 756
Score = 251 bits (640), Expect = 2e-66
Identities = 194/570 (34%), Positives = 250/570 (43%), Gaps = 82/570 (14%)
Query: 38 FLLLLPLASALQPTPLPFQELRLVGGPSRCR-GRLEVMHGGSWGSVCDDDWDVVDANVVC 96
FLLLL +P L +LRLVG S+ GRLEV+H G WG+VCDD++ + +A V C
Sbjct: 12 FLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVAC 71
Query: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
RQLG AL +GQG GPI LDNV C G E++L +CGS GWGV +C H EDV V+
Sbjct: 72 RQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVI 131
Query: 157 CDEFLPTQPPTRKMLTSRAPPTTL-PNGKSEGSVRL---VGGAN----LCQGRVEILHSG 208
C P + S L P G+ VRL + A + +G VE+ + G
Sbjct: 132 C------HPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEG 185
Query: 209 LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY----------------GTGHIL 252
W VCD W + ++ VVC LG + + ++ +
Sbjct: 186 HWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
Query: 253 LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQT 312
+ V C G EP +A CQ V C G ++ + R +T
Sbjct: 246 IHQVTCLGTEPHMANCQ-----VQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP---KT 297
Query: 313 DPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDD 372
P G +WA + R+RL G GRVEVL WGTVCD
Sbjct: 298 KPQRKG---------------SWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHR 339
Query: 373 WDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHN 432
W+ A V CR+ G G A A G G GP+ L V C G E LSDC L Q+
Sbjct: 340 WNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNG 399
Query: 433 CGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR-PRDGHLRLVNGAHRCEGRVELYLG 491
C H DA C P +G Q Q R+ R P +G L E +VE+
Sbjct: 400 CQHENDAAVRCNVP-NMGFQNQ------VRLAGGRIPEEGLL---------EVQVEVNGV 443
Query: 492 QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHF---GPGRGPILLDNVKCRGEESA 548
RWG+VC + W L A V CRQLG G A+ A E F P +++ V+C G E A
Sbjct: 444 PRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELA 503
Query: 549 LLLCSHIRWDAHNCDHSED---ASVLCQPS 575
L C R +C H A V C S
Sbjct: 504 LQQCQ--RHGPVHCSHGGGRFLAGVSCMDS 531
>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
Length = 774
Score = 225 bits (574), Expect = 7e-59
Identities = 168/515 (32%), Positives = 227/515 (44%), Gaps = 65/515 (12%)
Query: 57 ELRLVGGPSR-CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQ 115
+LRL G + GR+EV + G WG+VCDDD+ + A+VVCR+LG A ++G+
Sbjct: 57 QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116
Query: 116 GRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRA 175
G GPI LDN+ C G EA L+ C S GWGV +C H EDV V+C + + P K S
Sbjct: 117 GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSD---KRIPGFKFDNSLI 173
Query: 176 PPTTLPNGKSEG-SVRLVGGAN-----LCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQ 229
N + E +R + + +G VE+ W +CD W ++ VVC
Sbjct: 174 NQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGM 233
Query: 230 LGCGAAMAATTNAFFGYGTGH---ILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGA 286
G T + + + ++ C G E +++C+ LG V
Sbjct: 234 FGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCK-LGPQV---SLDPMKNV 289
Query: 287 LCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL 346
C P ++ +P D GP R+ A + +RL
Sbjct: 290 TCENGLPAVVSCVPGQVFSPD------------GPSRFRK---------AYKPEQPLVRL 328
Query: 347 VGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPV 406
GG GRVEVL G WGTVCDD WD A V CRE G G A A G G GP+
Sbjct: 329 RGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPI 388
Query: 407 LLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTP 466
L+ + C G E + DC Q C H EDAG C P +GLQ +
Sbjct: 389 HLNEIQCTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTP-AMGLQKK------------ 434
Query: 467 RPRDGHLRLVNGAHRCEGRVELYLGQR----WGTVCDDAWDLRAAGVLCRQLGCGQALAA 522
LRL G + EGRVE+ + + WG VC W + A V+CRQLG G A A
Sbjct: 435 ------LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNA 488
Query: 523 PGEAHFGPG---RGPILLDNVKCRGEESALLLCSH 554
E + G +++ VKC G E +L C H
Sbjct: 489 FQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRH 523
Score = 191 bits (484), Expect = 2e-48
Identities = 134/387 (34%), Positives = 181/387 (46%), Gaps = 44/387 (11%)
Query: 199 QGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHC 258
+GRVE+ + G WGTVCDDD+ + A VVCR+LG A + T ++ +G G G I LDN+HC
Sbjct: 69 EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128
Query: 259 EGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATG 318
G E LAAC S GWGV +C H ED G +C+ P + D +
Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF--------KFDNSLINQIENLN 180
Query: 319 VGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADA 378
+ + R A+L+T K++ + G VEV W +CD W ++
Sbjct: 181 IQVEDIRIRAILSTYR----KRTPVME---------GYVEVKEGKTWKQICDKHWTAKNS 227
Query: 379 RVACREAGC-GPALGATGLGHFGYGRG-----PVLLDNVGCAGTEARLSDCFHLG----- 427
RV C G G T + R P +D C GTEA +S C LG
Sbjct: 228 RVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSC-KLGPQVSL 283
Query: 428 --WGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGR 485
C + A C G DG R +P +RL GA+ EGR
Sbjct: 284 DPMKNVTCENGLPAVVSCVP----GQVFSPDGPSRFR-KAYKPEQPLVRLRGGAYIGEGR 338
Query: 486 VELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGE 545
VE+ WGTVCDD WDL +A V+CR+LG G A A + G G GPI L+ ++C G
Sbjct: 339 VEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGN 398
Query: 546 ESALLLCSHIRWDAHNCDHSEDASVLC 572
E +++ C ++ C+H EDA V C
Sbjct: 399 EKSIIDCK-FNAESQGCNHEEDAGVRC 424
Score = 144 bits (364), Expect = 2e-34
Identities = 120/383 (31%), Positives = 153/383 (39%), Gaps = 85/383 (22%)
Query: 69 GRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPL------AFGQGRGPILL 122
G +EV G +W +CD W ++ VVC G P R F R
Sbjct: 204 GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG----FPGERTYNTKVYKMFASRRKQRYW 259
Query: 123 D-NVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTL- 180
+++C G EA +S C + V C+ LP + S P
Sbjct: 260 PFSMDCTGTEAHISSCKLGPQVSLDPMKN----VTCENGLPA-------VVSCVPGQVFS 308
Query: 181 PNGKS---------EGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
P+G S + VRL GGA + +GRVE+L +G WGTVCDD W L A+VVCR+LG
Sbjct: 309 PDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELG 368
Query: 232 CGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGL 291
G+A A T + G G G I L+ + C G E + C+ C H EDAG C
Sbjct: 369 FGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCK-FNAESQGCNHEEDAGVRC--- 424
Query: 292 GPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPG 351
T A KK LRL GG
Sbjct: 425 ---------------------------------------NTPAMGLQKK---LRLNGGRN 442
Query: 352 PCRGRVEVLHAGG----WGTVCDDDWDFADARVACREAGCGPALGA---TGLGHFGYGRG 404
P GRVEVL WG VC +W +A V CR+ G G A A T H
Sbjct: 443 PYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSN 502
Query: 405 PVLLDNVGCAGTEARLSDCFHLG 427
V++ V C+GTE L+ C H G
Sbjct: 503 KVVMSGVKCSGTELSLAHCRHDG 525
Score = 139 bits (351), Expect = 5e-33
Identities = 88/245 (35%), Positives = 119/245 (48%), Gaps = 31/245 (12%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
+RL GG GR+EV+ G WG+VCDD WD+V A+VVCR+LG G A GQG
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177
GPI L+ ++C G E ++ +C C H ED V C+
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFNAES-QGCNHEEDAGVRCN------------------- 425
Query: 178 TTLPNGKSEGSVRLVGGANLCQGRVEIL----HSGLWGTVCDDDWGLPDAAVVCRQLGCG 233
P + +RL GG N +GRVE+L S +WG VC +WG+ +A VVCRQLG G
Sbjct: 426 --TPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLG 483
Query: 234 AAMAATTNAFFGYG---TGHILLDNVHCEGGEPRLAACQSLGWGV--HNCGHHEDAGALC 288
A A ++ +G + +++ V C G E LA C+ G V G AG C
Sbjct: 484 FASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVAC 543
Query: 289 AGLGP 293
+ P
Sbjct: 544 SETAP 548
Score = 60.5 bits (145), Expect = 4e-09
Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 7/93 (7%)
Query: 56 QELRLVGGPSRCRGRLEVM--HGGS--WGSVCDDDWDVVDANVVCRQLGCGLALPVPRPL 111
++LRL GG + GR+EV+ GS WG VC +W +V+A VVCRQLG G A +
Sbjct: 433 KKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQET 492
Query: 112 AFGQG---RGPILLDNVECRGQEAALSECGSRG 141
+ G +++ V+C G E +L+ C G
Sbjct: 493 WYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525
>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
Length = 753
Score = 224 bits (570), Expect = 2e-58
Identities = 165/513 (32%), Positives = 224/513 (43%), Gaps = 70/513 (13%)
Query: 59 RLVGGPSR-CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
RL G P + GR+E+ G WG++CDDD+ + A+++CR+LG A +G G
Sbjct: 45 RLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGT 104
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC-DEFLPTQPPTRKMLTSRAP 176
G I LDN+ C G E +++EC SRGWG +C H ED V+C D+ LP + +
Sbjct: 105 GRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHL 164
Query: 177 PTTLPNGKSEGSVRLVGGAN-----LCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
E +R G + +G VE+ W VCD W ++ VVC LG
Sbjct: 165 QV------EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG 218
Query: 232 CGAAMAATTNAFF---GYGTGHIL-LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGAL 287
+ AF+ H L V C G E L+ C SL + + + A
Sbjct: 219 FPSEKRVNA-AFYRLLAQRQQHSFGLHGVACVGTEAHLSLC-SLEF------YRANDTAR 270
Query: 288 CAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLV 347
C G GP ++ +P A G + +++ + R+RL
Sbjct: 271 CPGGGPAVVSCVPGPVY-----------AASSGQKKQQQSK---------PQGEARVRLK 310
Query: 348 GGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVL 407
GG P GRVEVL A WGTVCD WD A V CRE G G A A G G G +
Sbjct: 311 GGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIH 370
Query: 408 LDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR 467
L V C+G E L C H +C H +DAG C P G+ET
Sbjct: 371 LSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLP--------YTGAET------- 415
Query: 468 PRDGHLRLVNGAHRCEGRVELYLG----QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAP 523
+RL G + EGRVE+ +G RWG +C D W A V CRQLG G A
Sbjct: 416 ----RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGL 471
Query: 524 GEAHFGPGRG--PILLDNVKCRGEESALLLCSH 554
E + +++ V+C G E +L C+H
Sbjct: 472 QETWYWDSGNITEVVMSGVRCTGTELSLDQCAH 504
Score = 198 bits (503), Expect = 1e-50
Identities = 137/388 (35%), Positives = 172/388 (44%), Gaps = 50/388 (12%)
Query: 199 QGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHC 258
+GRVEI +G WGT+CDDD+ L A ++CR+LG A T +A +G GTG I LDN+ C
Sbjct: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
Query: 259 EGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATG 318
G E + C S GWG +C H EDAG +C P + S+ + Q +
Sbjct: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFS--DSNVIEVEHHLQVE----- 167
Query: 319 VGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADA 378
E + W GR L G VEV GW VCD W ++
Sbjct: 168 -------EVRIRPAVGW------GRRPLP----VTEGLVEVRLPDGWSQVCDKGWSAHNS 210
Query: 379 RVACREAGCGPA----------LGATGLGHFGYGRGPVLLDNVGCAGTEARLSDC---FH 425
V C G L FG L V C GTEA LS C F+
Sbjct: 211 HVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG-------LHGVACVGTEAHLSLCSLEFY 263
Query: 426 LGWGQHNCGHHEDAGALCA-GPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEG 484
C A C GP + G + + P+ + +RL GAH EG
Sbjct: 264 RANDTARCPGGGPAVVSCVPGP----VYAASSGQKKQQQSKPQG-EARVRLKGGAHPGEG 318
Query: 485 RVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRG 544
RVE+ WGTVCD WDL AA V+CR+LG G A A A G G G I L V+C G
Sbjct: 319 RVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSG 378
Query: 545 EESALLLCSHIRWDAHNCDHSEDASVLC 572
+E +L C H A +C HS+DA V C
Sbjct: 379 QELSLWKCPHKNITAEDCSHSQDAGVRC 406
Score = 143 bits (361), Expect = 4e-34
Identities = 121/387 (31%), Positives = 156/387 (40%), Gaps = 59/387 (15%)
Query: 69 GRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVP----RPLAFGQGRGPILLDN 124
G +EV W VCD W +++VVC LG V R LA Q L
Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS-FGLHG 245
Query: 125 VECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGK 184
V C G EA LS C + ++ +P P + + P G
Sbjct: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPG-PVYAASSGQKKQQQSKPQG- 303
Query: 185 SEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFF 244
E VRL GGA+ +GRVE+L + WGTVCD W L A+VVCR+LG G+A A + A
Sbjct: 304 -EARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARM 362
Query: 245 GYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSAT 304
G G G I L V C G E L C +C H +DAG C
Sbjct: 363 GQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL-------------- 408
Query: 305 REDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL-VGGPGPCRGRVEVLHAG 363
P ET + + + GR+ + +GGPGP R
Sbjct: 409 ----------------PYTGAETRIRLSGG--RSQHEGRVEVQIGGPGPLR--------- 441
Query: 364 GWGTVCDDDWDFADARVACREAGCGPAL-GATGLGHFGYGR-GPVLLDNVGCAGTEARLS 421
WG +C DDW +A VACR+ G G A G ++ G V++ V C GTE L
Sbjct: 442 -WGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLD 500
Query: 422 DCFHLGWGQH----NCGHHEDAGALCA 444
C H G H G AG +C+
Sbjct: 501 QCAH--HGTHITCKRTGTRFTAGVICS 525
Score = 132 bits (333), Expect = 7e-31
Identities = 85/250 (34%), Positives = 116/250 (46%), Gaps = 31/250 (12%)
Query: 49 QPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVP 108
Q P +RL GG GR+EV+ +WG+VCD WD+ A+VVCR+LG G A
Sbjct: 298 QSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREAL 357
Query: 109 RPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTR 168
GQG G I L V C GQE +L +C + +C H +D V C+
Sbjct: 358 SGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN---------- 407
Query: 169 KMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG----LWGTVCDDDWGLPDAA 224
LP +E +RL GG + +GRVE+ G WG +C DDWG +A
Sbjct: 408 -----------LPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM 456
Query: 225 VVCRQLGCGAAMAATTNAFFGYGTGHI---LLDNVHCEGGEPRLAACQSLGWGV--HNCG 279
V CRQLG G A ++ + +G+I ++ V C G E L C G + G
Sbjct: 457 VACRQLGLGYANHGLQETWY-WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTG 515
Query: 280 HHEDAGALCA 289
AG +C+
Sbjct: 516 TRFTAGVICS 525
Score = 127 bits (318), Expect = 4e-29
Identities = 88/256 (34%), Positives = 112/256 (43%), Gaps = 27/256 (10%)
Query: 337 AGKKSGRLRLVGGPG-PCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
AG + R RL G P P GRVE+ AG WGT+CDDD+ A + CRE G A G T
Sbjct: 37 AGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTH 96
Query: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQ--- 452
+G G G + LDN+ C+GTE +++C GWG +C H EDAG +C G
Sbjct: 97 SAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN 156
Query: 453 -VQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511
++ + RP G R EG VE+ L W VCD W + V+C
Sbjct: 157 VIEVEHHLQVEEVRIRPAVGWGR--RPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVC 214
Query: 512 RQLGCG----------QALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCS---HIRWD 558
LG + LA + FG L V C G E+ L LCS + D
Sbjct: 215 GMLGFPSEKRVNAAFYRLLAQRQQHSFG-------LHGVACVGTEAHLSLCSLEFYRAND 267
Query: 559 AHNCDHSEDASVLCQP 574
C A V C P
Sbjct: 268 TARCPGGGPAVVSCVP 283
>gi|194018748 CD6 molecule [Homo sapiens]
Length = 668
Score = 174 bits (442), Expect = 2e-43
Identities = 144/431 (33%), Positives = 170/431 (39%), Gaps = 115/431 (26%)
Query: 173 SRAPPTTLPNGKSEGS---------VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDA 223
S APP L +E VRL G++ C G VE+ W C W A
Sbjct: 20 SPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAA 79
Query: 224 AVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHED 283
V C++LG CG E
Sbjct: 80 EAV-----------------------------------------CRALG-----CGGAEA 93
Query: 284 AGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWA------- 336
A L PPT P A A T +A L + A W
Sbjct: 94 ASQLA----PPTPELPPPPA-----AGNTSVAANAT--LAGAPALLCSGAEWRLCEVVEH 142
Query: 337 AGKKSGR-----------LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREA 385
A + GR LRLV G G C GRVE+L G WG+VCDD WD DA V CR+
Sbjct: 143 ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
Query: 386 GCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445
GCG A+ A HF GRGP+ D V C+G EA L DC L GQH CGH EDAGA+C+
Sbjct: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSE 261
Query: 446 PEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLR 505
+ RL GA RCEG+VE++ W TVCD W
Sbjct: 262 HQS------------------------WRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297
Query: 506 AAGVLCRQLGCGQALAAP-GEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDH 564
A VLC+ LGCG A+ P G H GR C GEE L CS +++ C
Sbjct: 298 EAKVLCQSLGCGTAVERPKGLPHSLSGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQ 352
Query: 565 SEDASVLCQPS 575
S A VLC S
Sbjct: 353 SLAARVLCSAS 363
Score = 169 bits (428), Expect = 6e-42
Identities = 134/400 (33%), Positives = 158/400 (39%), Gaps = 86/400 (21%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG-------LALPVPRP 110
+RL G S C G +EV SW C WD A VCR LGCG LA P P
Sbjct: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
Query: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKM 170
+ N G A L C W + E V C +
Sbjct: 105 PPPPAAGNTSVAANATLAGAPALL--CSGAEWRL-----CEVVEHAC-----------RS 146
Query: 171 LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQL 230
RA T N ++RLV G C GRVE+L G WG+VCDD W L DA VVCRQL
Sbjct: 147 DGRRARVTCAEN----RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202
Query: 231 GCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290
GCG A+ A F G G I D V+C G E L C L G H CGH EDAGA+C+
Sbjct: 203 GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCS- 260
Query: 291 LGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGP 350
E +W RL GG
Sbjct: 261 ---------------EHQSW----------------------------------RLTGGA 271
Query: 351 GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL-GATGLGHFGYGRGPVLLD 409
C G+VEV G W TVCD +W ++A+V C+ GCG A+ GL H GR
Sbjct: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGR-----M 326
Query: 410 NVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449
C G E LS+C + C A LC+ L
Sbjct: 327 YYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366
Score = 130 bits (328), Expect = 3e-30
Identities = 93/261 (35%), Positives = 114/261 (43%), Gaps = 29/261 (11%)
Query: 321 PQPSRETALLTTAA----WAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFA 376
P P+ L T++A W G++ +RL G C G VEV W C WD
Sbjct: 19 PSPAPPDQLNTSSAESELWEPGERLP-VRLTNGSSSCSGTVEVRLEASWEPACGALWDSR 77
Query: 377 DARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHH 436
A CR GCG A A+ L P L T +
Sbjct: 78 AAEAVCRALGCGGAEAASQLA----PPTPELPPPPAAGNTSVAANATL------------ 121
Query: 437 EDAGA---LCAGPEELGLQVQQDG--SETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLG 491
AGA LC+G E +V + S+ R + LRLV+G C GRVE+
Sbjct: 122 --AGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEH 179
Query: 492 QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLL 551
WG+VCDD WDL A V+CRQLGCG A+ A HF PGRGPI D V C G E+ L
Sbjct: 180 GEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWD 239
Query: 552 CSHIRWDAHNCDHSEDASVLC 572
C + H C H EDA +C
Sbjct: 240 CPGLP-GQHYCGHKEDAGAVC 259
Score = 68.9 bits (167), Expect = 1e-11
Identities = 39/103 (37%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 56 QELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG- 114
Q RL GG RC G++EV G W +VCD +W +A V+C+ LGCG A+ P+ L
Sbjct: 263 QSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL 322
Query: 115 QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
GR C G+E LS C R + C VLC
Sbjct: 323 SGR-----MYYSCNGEELTLSNCSWRFNNSNLCSQSLAARVLC 360
>gi|5031863 galectin 3 binding protein [Homo sapiens]
Length = 585
Score = 115 bits (288), Expect = 1e-25
Identities = 54/110 (49%), Positives = 64/110 (58%)
Query: 334 AWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGA 393
A G G +RL G +GRVE+ + G WGTVCD+ WD DA V CR G A A
Sbjct: 14 AGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQA 73
Query: 394 TGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443
G FG G GP++LD V C GTEA L+DC LGW + NC H DAG +C
Sbjct: 74 LGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 114 bits (286), Expect = 2e-25
Identities = 56/106 (52%), Positives = 66/106 (62%)
Query: 183 GKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNA 242
G ++G +RL G QGRVEI + G WGTVCD+ W L DA+VVCR LG A A A
Sbjct: 18 GVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRA 77
Query: 243 FFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288
FG G+G I+LD V C G E LA C+SLGW NC H DAG +C
Sbjct: 78 AFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 108 bits (271), Expect = 1e-23
Identities = 50/103 (48%), Positives = 64/103 (62%)
Query: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529
DG +RL +G +GRVE++ +WGTVCD+ WDL A V+CR LG A A G A FG
Sbjct: 21 DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFG 80
Query: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G GPI+LD V+C G E++L C + W NC H DA V+C
Sbjct: 81 QGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 108 bits (269), Expect = 2e-23
Identities = 49/101 (48%), Positives = 66/101 (65%)
Query: 57 ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116
++RL G + +GR+E+ + G WG+VCD+ WD+ DA+VVCR LG A AFGQG
Sbjct: 23 DMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQG 82
Query: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
GPI+LD V+C G EA+L++C S GW NC H D V+C
Sbjct: 83 SGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
Length = 782
Score = 112 bits (279), Expect = 1e-24
Identities = 56/107 (52%), Positives = 69/107 (64%), Gaps = 3/107 (2%)
Query: 469 RDGHLRLVN--GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEA 526
RDG +RLV G GRVE+++G RWGTVCDD+W++ A V+CRQLG A+ A A
Sbjct: 669 RDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRA 728
Query: 527 HFGPGRG-PILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
FG G PILLD+V+C G E LL C H HNC+H EDA V+C
Sbjct: 729 EFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVC 775
Score = 108 bits (269), Expect = 2e-23
Identities = 58/111 (52%), Positives = 65/111 (58%), Gaps = 3/111 (2%)
Query: 186 EGSVRLVGGANLCQG--RVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAF 243
+G VRLV A L G RVE+ G WGTVCDD W + AAVVCRQLG A+ A A
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729
Query: 244 FGYGTG-HILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGP 293
FG G ILLD+V C G E L CQ G G HNC H EDAG +C+ P
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNP 780
Score = 102 bits (253), Expect = 1e-21
Identities = 67/166 (40%), Positives = 83/166 (50%), Gaps = 20/166 (12%)
Query: 294 PTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRL--------- 344
PT A P+ A R P+ T P+P+R T + G++ GRL
Sbjct: 616 PTARA-PTRAPRRGRPTAAPPAPT---PRPARPTQQPGSRR-GGGRRRGRLNSASRAFRD 670
Query: 345 ---RLV--GGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHF 399
RLV G GRVEV G WGTVCDD W+ + A V CR+ G A+ A F
Sbjct: 671 GEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEF 730
Query: 400 GYGRG-PVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCA 444
G G P+LLD+V CAG E L +C H G G HNC H EDAG +C+
Sbjct: 731 GQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776
Score = 102 bits (253), Expect = 1e-21
Identities = 55/109 (50%), Positives = 64/109 (58%), Gaps = 3/109 (2%)
Query: 57 ELRLV--GGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114
E+RLV G S GR+EV GG WG+VCDD W++ A VVCRQLG A+ + FG
Sbjct: 672 EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731
Query: 115 QGRG-PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162
QG PILLD+V C G E L EC G G HNC H ED V+C P
Sbjct: 732 QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNP 780
>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
sapiens]
Length = 451
Score = 108 bits (271), Expect = 1e-23
Identities = 50/107 (46%), Positives = 64/107 (59%)
Query: 51 TPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRP 110
T PF ++RLVGG GR+E++H G WG++CDD W+V VVCR LG V +
Sbjct: 343 TLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKA 402
Query: 111 LAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
FGQG GPI L+ V C G+E+++ EC R WG C H ED V C
Sbjct: 403 AHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449
Score = 105 bits (263), Expect = 9e-23
Identities = 46/101 (45%), Positives = 58/101 (57%)
Query: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402
++RLVGG GP GRVE+LH+G WGT+CDD W+ +V CR G HFG G
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408
Query: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443
GP+ L+ V C G E+ + +C WG C H EDAG C
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449
Score = 105 bits (261), Expect = 1e-22
Identities = 51/100 (51%), Positives = 58/100 (58%)
Query: 189 VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGT 248
VRLVGG+ +GRVEILHSG WGT+CDD W + VVCR LG A A FG GT
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409
Query: 249 GHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288
G I L+ V C G E + C+ WG C H EDAG C
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449
Score = 100 bits (248), Expect = 5e-21
Identities = 52/121 (42%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
Query: 452 QVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511
Q + GS T P + +RLV G+ EGRVE+ +WGT+CDD W++R V+C
Sbjct: 334 QKGEKGSGNTLTPFTK-----VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVC 388
Query: 512 RQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVL 571
R LG A AHFG G GPI L+ V C G ES++ C +W C HSEDA V
Sbjct: 389 RSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVT 448
Query: 572 C 572
C
Sbjct: 449 C 449
>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
Length = 495
Score = 105 bits (263), Expect = 9e-23
Identities = 49/100 (49%), Positives = 61/100 (61%)
Query: 473 LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGR 532
+RLVNG+ EGRVE+Y +RWGTVCDD WD + V+CR LG A FG G
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452
Query: 533 GPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G I +D+V C+G E + CS +W NC H+EDASV C
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492
Score = 102 bits (254), Expect = 1e-21
Identities = 48/100 (48%), Positives = 56/100 (56%)
Query: 189 VRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGT 248
+RLV G+ +GRVE+ H WGTVCDD W D VVCR LG A FG GT
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452
Query: 249 GHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288
G I +D+V C+G E + C WGV NCGH EDA C
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492
Score = 100 bits (250), Expect = 3e-21
Identities = 48/101 (47%), Positives = 58/101 (57%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
+RLV G GR+EV H WG+VCDD WD D +VVCR LG V R FGQG
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCD 158
G I +D+V C+G E + C WGV NC H ED +V C+
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 98.2 bits (243), Expect = 2e-20
Identities = 51/112 (45%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 337 AGKKSG-----RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPAL 391
AG SG +RLV G GP GRVEV H WGTVCDD WD D V CR G
Sbjct: 381 AGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVE 440
Query: 392 GATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443
FG G G + +D+V C GTE + C WG NCGH EDA C
Sbjct: 441 EVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492
>gi|5803080 macrophage receptor with collagenous structure [Homo
sapiens]
Length = 520
Score = 103 bits (258), Expect = 3e-22
Identities = 51/107 (47%), Positives = 63/107 (58%), Gaps = 5/107 (4%)
Query: 183 GKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNA 242
G++ SVR+VG +N +GR E+ +SG WGT+CDD+W DA V CR LG A
Sbjct: 418 GENSVSVRIVGSSN--RGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYK-- 473
Query: 243 FFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCA 289
G GTG I LDNV C G E L +C WG H+C H EDAG C+
Sbjct: 474 -VGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519
Score = 96.3 bits (238), Expect = 7e-20
Identities = 48/107 (44%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
Query: 338 GKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLG 397
G+ S +R+VG RGR EV ++G WGT+CDD+W +DA V CR G L
Sbjct: 418 GENSVSVRIVGSSN--RGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG---RALY 472
Query: 398 HFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCA 444
G G G + LDNV C GTE+ L C WG H+C H EDAG C+
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519
Score = 92.4 bits (228), Expect = 1e-18
Identities = 45/100 (45%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 58 LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
+R+VG +R GR EV + G+WG++CDD+W DA V CR LG + + G G
Sbjct: 424 VRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYK---VGAGT 478
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
G I LDNV+CRG E+ L C WG H+C H ED V C
Sbjct: 479 GQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518
Score = 87.8 bits (216), Expect = 2e-17
Identities = 45/100 (45%), Positives = 55/100 (55%), Gaps = 5/100 (5%)
Query: 473 LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGR 532
+R+V ++R GR E+Y WGT+CDD W A V CR LG + A G G
Sbjct: 424 VRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRAL---YKVGAGT 478
Query: 533 GPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
G I LDNV+CRG ES L C+ W H+C H EDA V C
Sbjct: 479 GQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518
>gi|166197668 CD5 molecule [Homo sapiens]
Length = 495
Score = 85.5 bits (210), Expect = 1e-16
Identities = 100/378 (26%), Positives = 140/378 (37%), Gaps = 85/378 (22%)
Query: 33 PQALSFLLLLPLASALQPTPL--PFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDW--- 87
P A +LL + +AS L P + RL S+C+G+LEV W VC W
Sbjct: 8 PLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRS 67
Query: 88 -----DVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILL-----DNVECRGQEAALSEC 137
D A+ VC++L CG+ L + GP L+ ++ C GQ + S C
Sbjct: 68 SKQWEDPSQASKVCQRLNCGVPLSL----------GPFLVTYTPQSSIICYGQLGSFSNC 117
Query: 138 G-SRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLV--GG 194
SR H+ + + C E T PP T+R PPTT P + ++LV G
Sbjct: 118 SHSRNDMCHS------LGLTCLEPQKTTPP-----TTRPPPTTTPEPTAPPRLQLVAQSG 166
Query: 195 ANLCQGRVEILHSGLWGTVCDD--DWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHIL 252
C G VE L GT+ + D +C L CG+ + G
Sbjct: 167 GQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQ---- 222
Query: 253 LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQT 312
+ GEPR + W + N SS T + ++
Sbjct: 223 ------DPGEPREHQPLPIQWKIQN-----------------------SSCTSLEHCFRK 253
Query: 313 DPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDD 372
+ PQ S L + + +S RLVGG C G VEV W +CD
Sbjct: 254 ------IKPQKSGRVLALLCSGFQPKVQS---RLVGGSSICEGTVEVRQGAQWAALCDSS 304
Query: 373 WDFADAR--VACREAGCG 388
+ R CRE CG
Sbjct: 305 SARSSLRWEEVCREQQCG 322
Score = 64.3 bits (155), Expect = 3e-10
Identities = 59/202 (29%), Positives = 78/202 (38%), Gaps = 25/202 (12%)
Query: 345 RLVGGPGPCRGRVEVLHAGGWGTVCDDDW--------DFADARVACREAGCGPALGATGL 396
RL C+G++EV GW VC W D + A C+ CG L L
Sbjct: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPL---SL 92
Query: 397 GHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQD 456
G F P ++ C G S+C H +++ H G C P++ +
Sbjct: 93 GPFLVTYTP--QSSIICYGQLGSFSNCSH---SRNDMCH--SLGLTCLEPQKTTPPTTRP 145
Query: 457 GSETTRVPTPRPRDGHLRLV--NGAHRCEGRVELYLGQRWGTVCDDAWDLR--AAGVLCR 512
TT PT PR L+LV +G C G VE Y G GT+ +A D LC
Sbjct: 146 PPTTTPEPTAPPR---LQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCN 202
Query: 513 QLGCGQALAAPGEAHFGPGRGP 534
L CG L E G + P
Sbjct: 203 NLQCGSFLKHLPETEAGRAQDP 224
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 23/102 (22%)
Query: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAW--------DLRAAGVLCRQLGCGQALA 521
D RL +C+G++E+YL W VC +W D A +C++L CG L+
Sbjct: 32 DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91
Query: 522 APGEAHFGPGRGPILL-----DNVKCRGEESALLLCSHIRWD 558
GP L+ ++ C G+ + CSH R D
Sbjct: 92 L----------GPFLVTYTPQSSIICYGQLGSFSNCSHSRND 123
Score = 45.8 bits (107), Expect = 1e-04
Identities = 79/349 (22%), Positives = 116/349 (33%), Gaps = 83/349 (23%)
Query: 190 RLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD--------AAVVCRQLGCGAAMAATTN 241
RL + CQG++E+ W VC WG A+ VC++L CG ++
Sbjct: 36 RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGP- 94
Query: 242 AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPS 301
+ + ++ C G LG NC H + +C LG LT L
Sbjct: 95 ----FLVTYTPQSSIICYG---------QLG-SFSNCSHSRND--MCHSLG---LTCLEP 135
Query: 302 SATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGP--CRGRVEV 359
T + P+ T P+P+ RL+LV G C G VE
Sbjct: 136 QKTTPPTT-RPPPTTT---PEPTAPP---------------RLQLVAQSGGQHCAGVVEF 176
Query: 360 LHAGGWGTVCDDDWDFAD--ARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417
GT+ + D C CG L G + P E
Sbjct: 177 YSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDP----------GE 226
Query: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQV--QQDGSETTRVPTPRPRDGHLRL 475
R + W N C E ++ Q+ G + + RL
Sbjct: 227 PREHQPLPIQWKIQNSS--------CTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRL 278
Query: 476 VNGAHRCEGRVELYLGQRWGTVCDDA-------WDLRAAGVLCRQLGCG 517
V G+ CEG VE+ G +W +CD + W+ +CR+ CG
Sbjct: 279 VGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVCREQQCG 322
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/208 (22%), Positives = 70/208 (33%), Gaps = 46/208 (22%)
Query: 43 PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVD--ANVVCRQLG 100
P + +PT P +L G C G +E G G++ + D N +C L
Sbjct: 146 PPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQ 205
Query: 101 CGLALPVPRPLAFGQGRGP------------ILLDNVECRGQEAALSECGSRGWGVHNCF 148
CG L G+ + P + N C E + + G
Sbjct: 206 CGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSG----- 260
Query: 149 HYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208
+A+LC F P + RLVGG+++C+G VE+
Sbjct: 261 --RVLALLCSGFQP-----------------------KVQSRLVGGSSICEGTVEVRQGA 295
Query: 209 LWGTVCDDDWGLPDA--AVVCRQLGCGA 234
W +CD VCR+ CG+
Sbjct: 296 QWAALCDSSSARSSLRWEEVCREQQCGS 323
>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
sapiens]
Length = 388
Score = 45.8 bits (107), Expect = 1e-04
Identities = 19/40 (47%), Positives = 24/40 (60%)
Query: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157
GPI L+ V C G+E+++ EC R WG C H ED V C
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
Score = 42.7 bits (99), Expect = 9e-04
Identities = 17/40 (42%), Positives = 22/40 (55%)
Query: 404 GPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALC 443
GP+ L+ V C G E+ + +C WG C H EDAG C
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
Score = 42.7 bits (99), Expect = 9e-04
Identities = 19/40 (47%), Positives = 23/40 (57%)
Query: 533 GPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572
GPI L+ V C G ES++ C +W C HSEDA V C
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
Score = 41.6 bits (96), Expect = 0.002
Identities = 18/41 (43%), Positives = 21/41 (51%)
Query: 248 TGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288
TG I L+ V C G E + C+ WG C H EDAG C
Sbjct: 346 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
>gi|58761492 Rho guanine nucleotide exchange factor (GEF) 10-like
isoform 1 [Homo sapiens]
Length = 1279
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 245 GYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSAT 304
G G ILL + + G L +C+S G C H L AGL TL A P ++
Sbjct: 897 GLQDGSILLYS-SVDTGTQCLVSCRSPGLQPVLCLRHSPFHLL-AGLQDGTLAAYPRTSG 954
Query: 305 REDWAWQTDPSATGVGPQPSRETALLTTAAWAA 337
W ++ P VGP P R L A WA+
Sbjct: 955 GVLWDLESPPVCLTVGPGPVRTLLSLEDAVWAS 987
>gi|74136547 Rho guanine nucleotide exchange factor (GEF) 10-like
isoform 2 [Homo sapiens]
Length = 1240
Score = 37.4 bits (85), Expect = 0.038
Identities = 31/93 (33%), Positives = 40/93 (43%), Gaps = 2/93 (2%)
Query: 245 GYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSAT 304
G G ILL + + G L +C+S G C H L AGL TL A P ++
Sbjct: 858 GLQDGSILLYS-SVDTGTQCLVSCRSPGLQPVLCLRHSPFHLL-AGLQDGTLAAYPRTSG 915
Query: 305 REDWAWQTDPSATGVGPQPSRETALLTTAAWAA 337
W ++ P VGP P R L A WA+
Sbjct: 916 GVLWDLESPPVCLTVGPGPVRTLLSLEDAVWAS 948
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 36.2 bits (82), Expect = 0.084
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 71 LEVMHGGSWGSVCDDDWDVVDANVVCRQLG 100
L+V SW ++C DDW ANV C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 33.9 bits (76), Expect = 0.42
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
Query: 182 NGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
+G+ E VGG N +++ + W T+C DDW A V C QLG
Sbjct: 100 DGEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 33.5 bits (75), Expect = 0.54
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 338 GKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAG 386
G+ R VGG ++V A W T+C DDW A VAC + G
Sbjct: 101 GEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 30.0 bits (66), Expect = 6.0
Identities = 11/30 (36%), Positives = 16/30 (53%)
Query: 486 VELYLGQRWGTVCDDAWDLRAAGVLCRQLG 515
++++ W T+C D W A V C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
sapiens]
Length = 344
Score = 36.2 bits (82), Expect = 0.084
Identities = 15/30 (50%), Positives = 18/30 (60%)
Query: 71 LEVMHGGSWGSVCDDDWDVVDANVVCRQLG 100
L+V SW ++C DDW ANV C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 33.9 bits (76), Expect = 0.42
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
Query: 182 NGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
+G+ E VGG N +++ + W T+C DDW A V C QLG
Sbjct: 100 DGEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 33.5 bits (75), Expect = 0.54
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 338 GKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAG 386
G+ R VGG ++V A W T+C DDW A VAC + G
Sbjct: 101 GEDEYRCVRVGGQNAV---LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
Score = 30.0 bits (66), Expect = 6.0
Identities = 11/30 (36%), Positives = 16/30 (53%)
Query: 486 VELYLGQRWGTVCDDAWDLRAAGVLCRQLG 515
++++ W T+C D W A V C QLG
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLG 146
>gi|239754935 PREDICTED: hypothetical protein [Homo sapiens]
Length = 397
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 319 VGPQPSRETALLTTAAWAAGKKSGRL--RLVGGPGPCRGRVEVLHAGGWG 366
+ P P E +L + AAW A K GRL R GG G GR E GWG
Sbjct: 217 LAPSPIPERSLRSLAAWEALGKGGRLGRRCRGGGGERAGRKEGCPLWGWG 266
>gi|239749477 PREDICTED: hypothetical protein XP_002347062 [Homo
sapiens]
Length = 397
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 319 VGPQPSRETALLTTAAWAAGKKSGRL--RLVGGPGPCRGRVEVLHAGGWG 366
+ P P E +L + AAW A K GRL R GG G GR E GWG
Sbjct: 217 LAPSPIPERSLRSLAAWEALGKGGRLGRRCRGGGGERAGRKEGCPLWGWG 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.477
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,957,150
Number of Sequences: 37866
Number of extensions: 1603850
Number of successful extensions: 4420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3767
Number of HSP's gapped (non-prelim): 291
length of query: 575
length of database: 18,247,518
effective HSP length: 108
effective length of query: 467
effective length of database: 14,157,990
effective search space: 6611781330
effective search space used: 6611781330
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.