Guide to the Human Genome
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Search of human proteins with 17017974

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17017974 wingless-type MMTV integration site family, member
11 precursor [Homo sapiens]
         (354 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17017974 wingless-type MMTV integration site family, member 1...   745   0.0  
gi|17402922 wingless-type MMTV integration site family, member 4...   314   9e-86
gi|14249180 wingless-type MMTV integration site family, member 5...   272   4e-73
gi|17402919 wingless-type MMTV integration site family, member 5...   272   4e-73
gi|40806205 wingless-type MMTV integration site family, member 5...   271   8e-73
gi|13540477 wingless-type MMTV integration site family, member 3...   267   9e-72
gi|14916475 wingless-type MMTV integration site family, member 3...   262   3e-70
gi|13518017 wingless-type MMTV integration site family, member 2...   260   1e-69
gi|13518021 wingless-type MMTV integration site family, member 2...   260   1e-69
gi|17402916 wingless-type MMTV integration site family, member 1...   259   2e-69
gi|17402914 wingless-type MMTV integration site family, member 1...   259   2e-69
gi|17505193 wingless-type MMTV integration site family, member 7...   258   7e-69
gi|17505191 wingless-type MMTV integration site family, member 7...   254   6e-68
gi|4885655 wingless-type MMTV integration site family, member 1 ...   253   2e-67
gi|4507927 wingless-type MMTV integration site family member 2 p...   250   2e-66
gi|16507239 wingless-type MMTV integration site family, member 6...   239   2e-63
gi|16936522 wingless-type MMTV integration site family, member 1...   235   5e-62
gi|16936520 wingless-type MMTV integration site family, member 1...   226   2e-59
gi|17505195 wingless-type MMTV integration site family, member 8...   207   1e-53
gi|110735437 wingless-type MMTV integration site family, member ...   206   3e-53
gi|17017976 wingless-type MMTV integration site family, member 9...   205   4e-53
gi|15082261 wingless-type MMTV integration site family, member 9...   204   1e-52
gi|239752226 PREDICTED: hypothetical protein XP_002348164 [Homo ...   107   1e-23
gi|13562088 leucine-rich repeat-containing 3 precursor [Homo sap...    35   0.078
gi|41327730 calponin 2 isoform b [Homo sapiens]                        32   0.86 
gi|4758018 calponin 2 isoform a [Homo sapiens]                         32   0.86 
gi|12751479 zinc finger protein 643 [Homo sapiens]                     30   2.5  
gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprot...    30   4.3  
gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprot...    30   4.3  
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    30   4.3  

>gi|17017974 wingless-type MMTV integration site family, member 11
           precursor [Homo sapiens]
          Length = 354

 Score =  745 bits (1923), Expect = 0.0
 Identities = 354/354 (100%), Positives = 354/354 (100%)

Query: 1   MRARPQVCEALLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCR 60
           MRARPQVCEALLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCR
Sbjct: 1   MRARPQVCEALLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCR 60

Query: 61  SNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAA 120
           SNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAA
Sbjct: 61  SNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAA 120

Query: 121 AISHAIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKK 180
           AISHAIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKK
Sbjct: 121 AISHAIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKK 180

Query: 181 TGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTR 240
           TGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTR
Sbjct: 181 TGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTR 240

Query: 241 YLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCN 300
           YLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCN
Sbjct: 241 YLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCN 300

Query: 301 KTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
           KTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK
Sbjct: 301 KTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354


>gi|17402922 wingless-type MMTV integration site family, member 4
           precursor [Homo sapiens]
          Length = 351

 Score =  314 bits (804), Expect = 9e-86
 Identities = 141/350 (40%), Positives = 219/350 (62%), Gaps = 1/350 (0%)

Query: 5   PQVCEALLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLE 64
           P+ C   L  L           WL L+K  S  ++++ + C++L+GL+  QVQ+C+ NLE
Sbjct: 3   PRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLE 62

Query: 65  LMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISH 124
           +M +V   A+  ++ C+  F + RWNCS+++  P +   + +GTRE+AFVYA+S+A ++ 
Sbjct: 63  VMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAF 122

Query: 125 AIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQ 184
           A+ RAC+SG+L  C C          G +W GC+DN++YG+     F D   +  K  S 
Sbjct: 123 AVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRER-SKGASS 181

Query: 185 ANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSA 244
           +  LM LHN+E GR+A+   + ++CKCHGVSGSC ++TCW+ +   + V   LK ++  A
Sbjct: 182 SRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGA 241

Query: 245 TKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSN 304
           T+V  R +G+ + LVP++   +P  D +LVYL+ SPDFC ++ + G  GT+ R CNKTS 
Sbjct: 242 TEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSK 301

Query: 305 GSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
             D C+L+CCGRG++     + ERC CK+HWCC+V CR+C+R VE + C+
Sbjct: 302 AIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR 351


>gi|14249180 wingless-type MMTV integration site family, member 5B
           precursor [Homo sapiens]
          Length = 359

 Score =  272 bits (695), Expect = 4e-73
 Identities = 139/335 (41%), Positives = 191/335 (57%), Gaps = 19/335 (5%)

Query: 36  ALALNQTQH-----------CKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAF 84
           +LALN  Q            C QL GL   Q +LC+   E M  +   A+  +K C+  F
Sbjct: 28  SLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQF 87

Query: 85  ADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVP 144
              RWNCS+ + A  +   ++ G+RE+AF +A+SAA + +AI+RAC  G+L  C C    
Sbjct: 88  RQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTA 147

Query: 145 GEPPGPGN-RWGGCADNLSYGLLMGAKFSDAPMK----VKKTGSQANKLMRLHNSEVGRQ 199
                P +  WGGC DN+ YG     +F DA  +     K +  Q   LM L N+E GR+
Sbjct: 148 RPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRR 207

Query: 200 ALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLV 259
           A+    ++ CKCHGVSGSCS++TCW  L E + V   LK +Y SA  +     G  + + 
Sbjct: 208 AVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVN 267

Query: 260 PKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYN 319
            +     P    +LVY+  SPD+C++NE  GS GTQ R CNKTS G D C+LMCCGRGYN
Sbjct: 268 SRFTQPTP---EDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYN 324

Query: 320 PYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
            +    VERCHCK+HWCC+V C++C   V++Y+CK
Sbjct: 325 QFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK 359


>gi|17402919 wingless-type MMTV integration site family, member 5B
           precursor [Homo sapiens]
          Length = 359

 Score =  272 bits (695), Expect = 4e-73
 Identities = 139/335 (41%), Positives = 191/335 (57%), Gaps = 19/335 (5%)

Query: 36  ALALNQTQH-----------CKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAF 84
           +LALN  Q            C QL GL   Q +LC+   E M  +   A+  +K C+  F
Sbjct: 28  SLALNPVQRPEMFIIGAQPVCSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQF 87

Query: 85  ADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVP 144
              RWNCS+ + A  +   ++ G+RE+AF +A+SAA + +AI+RAC  G+L  C C    
Sbjct: 88  RQRRWNCSTADNASVFGRVMQIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTA 147

Query: 145 GEPPGPGN-RWGGCADNLSYGLLMGAKFSDAPMK----VKKTGSQANKLMRLHNSEVGRQ 199
                P +  WGGC DN+ YG     +F DA  +     K +  Q   LM L N+E GR+
Sbjct: 148 RPKDLPRDWLWGGCGDNVEYGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRR 207

Query: 200 ALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLV 259
           A+    ++ CKCHGVSGSCS++TCW  L E + V   LK +Y SA  +     G  + + 
Sbjct: 208 AVYKMADVACKCHGVSGSCSLKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVN 267

Query: 260 PKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYN 319
            +     P    +LVY+  SPD+C++NE  GS GTQ R CNKTS G D C+LMCCGRGYN
Sbjct: 268 SRFTQPTP---EDLVYVDPSPDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYN 324

Query: 320 PYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
            +    VERCHCK+HWCC+V C++C   V++Y+CK
Sbjct: 325 QFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYICK 359


>gi|40806205 wingless-type MMTV integration site family, member 5A
           precursor [Homo sapiens]
          Length = 380

 Score =  271 bits (692), Expect = 8e-73
 Identities = 131/315 (41%), Positives = 184/315 (58%), Gaps = 8/315 (2%)

Query: 45  CKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDL 104
           C QL GL   Q +LC    + M  +   A+  +K C+  F   RWNCS+++    +   +
Sbjct: 69  CSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDNTSVFGRVM 128

Query: 105 ERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPGEPPGPGN-RWGGCADNLSY 163
           + G+RE+AF YA+SAA + +A++RAC  G+L  C C         P +  WGGC DN+ Y
Sbjct: 129 QIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWGGCGDNIDY 188

Query: 164 GLLMGAKFSDAPMK----VKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCS 219
           G     +F DA  +     K +   A  LM LHN+E GR+ +    ++ CKCHGVSGSCS
Sbjct: 189 GYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCHGVSGSCS 248

Query: 220 IRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSS 279
           ++TCW  L + + V   LK +Y SA  +    + +R  LV  +         +LVY+  S
Sbjct: 249 LKTCWLQLADFRKVGDALKEKYDSAAAM---RLNSRGKLVQVNSRFNSPTTQDLVYIDPS 305

Query: 280 PDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYV 339
           PD+C++NE  GS GTQ R CNKTS G D C+LMCCGRGY+ +     ERCHCK+HWCCYV
Sbjct: 306 PDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFHWCCYV 365

Query: 340 TCRRCERTVERYVCK 354
            C++C   V+++VCK
Sbjct: 366 KCKKCTEIVDQFVCK 380


>gi|13540477 wingless-type MMTV integration site family, member 3
           [Homo sapiens]
          Length = 355

 Score =  267 bits (683), Expect = 9e-72
 Identities = 131/338 (38%), Positives = 205/338 (60%), Gaps = 11/338 (3%)

Query: 23  YGIKW-LALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACR 81
           Y I W LAL +  ++L  +Q   C  + GLV  Q++ CR+ +E+M +V    +  ++ C+
Sbjct: 23  YPIWWSLALGQQYTSLG-SQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQ 81

Query: 82  RAFADMRWNCSSIELAPNYLLD-LERGTRESAFVYALSAAAISHAIARACTSGDLPGCSC 140
             F   RWNC++I+ +       L++ TRESAFV+A+++A ++ A+ R+C  G    C C
Sbjct: 82  HQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGC 141

Query: 141 GPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQA 200
                 PPG G +WGGC+++  +G+L+  +F+DA    ++    A   M  HN+E GR  
Sbjct: 142 DSHHKGPPGEGWKWGGCSEDADFGVLVSREFADA----RENRPDARSAMNKHNNEAGRTT 197

Query: 201 LRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVV---HRPM-GTRK 256
           +   + +KCKCHG+SGSC ++TCW    + + +   LK +Y SA+++V   HR   G  +
Sbjct: 198 ILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVE 257

Query: 257 HLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGR 316
            L  K    +P  + +LVY ++SP+FC  N + GS GT+DR CN TS+G D CDL+CCGR
Sbjct: 258 TLRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGR 317

Query: 317 GYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
           G+N  T++  E+CHC +HWCCYV+C+ C R  + + CK
Sbjct: 318 GHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK 355


>gi|14916475 wingless-type MMTV integration site family, member 3A
           [Homo sapiens]
          Length = 352

 Score =  262 bits (670), Expect = 3e-70
 Identities = 124/334 (37%), Positives = 202/334 (60%), Gaps = 10/334 (2%)

Query: 27  WLALSKTPSALAL-NQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFA 85
           W +L+  P   +L +Q   C  + GLV  Q++ CR+ +E+M +V    +  ++ C+  F 
Sbjct: 23  WWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFR 82

Query: 86  DMRWNCSSI-ELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVP 144
             RWNC+++ +    +   L++ TRESAFV+A+++A ++ A+ R+C  G    C C    
Sbjct: 83  GRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRH 142

Query: 145 GEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRAS 204
              PG G +WGGC++++ +G ++  +F+DA    ++    A   M  HN+E GRQA+ + 
Sbjct: 143 QGSPGKGWKWGGCSEDIEFGGMVSREFADA----RENRPDARSAMNRHNNEAGRQAIASH 198

Query: 205 LEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVV---HRPM-GTRKHLVP 260
           + +KCKCHG+SGSC ++TCW    + + +   LK +Y SA+++V   HR   G  + L P
Sbjct: 199 MHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRP 258

Query: 261 KDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNP 320
           +    +   + +LVY ++SP+FC  N + GS GT+DR CN +S+G D CDL+CCGRG+N 
Sbjct: 259 RYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNA 318

Query: 321 YTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
             +R  E+C C +HWCCYV+C+ C R  + + CK
Sbjct: 319 RAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK 352


>gi|13518017 wingless-type MMTV integration site family, member 2B
           isoform WNT-2B1 [Homo sapiens]
          Length = 372

 Score =  260 bits (665), Expect = 1e-69
 Identities = 132/322 (40%), Positives = 188/322 (58%), Gaps = 11/322 (3%)

Query: 38  ALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELA 97
           AL     C  + GLVS Q QLC+   ++M +V   ARE ++ C+  F   RWNC++++  
Sbjct: 46  ALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRD 105

Query: 98  PNYL-LDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPG----EPPGPGN 152
                  + R +RE+AFVYA+S+A + HAI RAC+ G+L  CSC P       +  G  +
Sbjct: 106 HTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFD 165

Query: 153 RWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCH 212
            WGGC+DN+ YG+     F DA  K  K    A  LM LHN+  GR A+R  L+++CKCH
Sbjct: 166 -WGGCSDNIHYGVRFAKAFVDAKEKRLK---DARALMNLHNNRCGRTAVRRFLKLECKCH 221

Query: 213 GVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSE 272
           GVSGSC++RTCW+ L + +     L+ RY  A +V+    G   +        R    ++
Sbjct: 222 GVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGA--NFTAARQGYRRATRTD 279

Query: 273 LVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCK 332
           LVY  +SPD+C+ ++  GS GT  R C+KTS G+D C++MCCGRGY+      V +C CK
Sbjct: 280 LVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECK 339

Query: 333 YHWCCYVTCRRCERTVERYVCK 354
           +HWCC V C+ C  TV+ + CK
Sbjct: 340 FHWCCAVRCKECRNTVDVHTCK 361


>gi|13518021 wingless-type MMTV integration site family, member 2B
           isoform WNT-2B2 [Homo sapiens]
          Length = 391

 Score =  260 bits (665), Expect = 1e-69
 Identities = 132/322 (40%), Positives = 188/322 (58%), Gaps = 11/322 (3%)

Query: 38  ALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELA 97
           AL     C  + GLVS Q QLC+   ++M +V   ARE ++ C+  F   RWNC++++  
Sbjct: 65  ALGARVICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDRD 124

Query: 98  PNYL-LDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPG----EPPGPGN 152
                  + R +RE+AFVYA+S+A + HAI RAC+ G+L  CSC P       +  G  +
Sbjct: 125 HTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFD 184

Query: 153 RWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCH 212
            WGGC+DN+ YG+     F DA  K  K    A  LM LHN+  GR A+R  L+++CKCH
Sbjct: 185 -WGGCSDNIHYGVRFAKAFVDAKEKRLK---DARALMNLHNNRCGRTAVRRFLKLECKCH 240

Query: 213 GVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSE 272
           GVSGSC++RTCW+ L + +     L+ RY  A +V+    G   +        R    ++
Sbjct: 241 GVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQDGA--NFTAARQGYRRATRTD 298

Query: 273 LVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCK 332
           LVY  +SPD+C+ ++  GS GT  R C+KTS G+D C++MCCGRGY+      V +C CK
Sbjct: 299 LVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECK 358

Query: 333 YHWCCYVTCRRCERTVERYVCK 354
           +HWCC V C+ C  TV+ + CK
Sbjct: 359 FHWCCAVRCKECRNTVDVHTCK 380


>gi|17402916 wingless-type MMTV integration site family, member 16
           isoform 1 precursor [Homo sapiens]
          Length = 365

 Score =  259 bits (663), Expect = 2e-69
 Identities = 122/319 (38%), Positives = 195/319 (61%), Gaps = 20/319 (6%)

Query: 51  LVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNC--------SSIELAPNYLL 102
           L S Q +LC+    L+ ++   AR  ++ C   F   RWNC        + +  +P +  
Sbjct: 52  LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGY 111

Query: 103 DLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPV--PGEPPGPGNRWGGCADN 160
           +L  GT+E+AF+YA+ AA + H++ R+C++G++  CSC      G     G  WGGC+D+
Sbjct: 112 ELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDD 171

Query: 161 LSYGLLMGAKFSDAPMKVKKTGSQANKL---MRLHNSEVGRQALRASLEMKCKCHGVSGS 217
           + YG+    KF D P  +  T  + NK+   M LHN+E GRQA+   + + C+CHGVSGS
Sbjct: 172 VQYGMWFSRKFLDFP--IGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGS 229

Query: 218 CSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIR--PVKDSELVY 275
           C+++TCWK +   + +   LK +Y ++ ++  +   T++ +  ++ D R  P+   +L+Y
Sbjct: 230 CAVKTCWKTMSSFEKIGHLLKDKYENSIQISDK---TKRKMRRREKDQRKIPIHKDDLLY 286

Query: 276 LQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHW 335
           +  SP++C++++K+G  GTQ R+CN+TS G+D C+L+CCGRGYN +  R VERC CK+ W
Sbjct: 287 VNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIW 346

Query: 336 CCYVTCRRCERTVERYVCK 354
           CCYV CRRCE   + + CK
Sbjct: 347 CCYVRCRRCESMTDVHTCK 365


>gi|17402914 wingless-type MMTV integration site family, member 16
           isoform 2 [Homo sapiens]
          Length = 355

 Score =  259 bits (663), Expect = 2e-69
 Identities = 122/319 (38%), Positives = 195/319 (61%), Gaps = 20/319 (6%)

Query: 51  LVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNC--------SSIELAPNYLL 102
           L S Q +LC+    L+ ++   AR  ++ C   F   RWNC        + +  +P +  
Sbjct: 42  LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGY 101

Query: 103 DLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPV--PGEPPGPGNRWGGCADN 160
           +L  GT+E+AF+YA+ AA + H++ R+C++G++  CSC      G     G  WGGC+D+
Sbjct: 102 ELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDD 161

Query: 161 LSYGLLMGAKFSDAPMKVKKTGSQANKL---MRLHNSEVGRQALRASLEMKCKCHGVSGS 217
           + YG+    KF D P  +  T  + NK+   M LHN+E GRQA+   + + C+CHGVSGS
Sbjct: 162 VQYGMWFSRKFLDFP--IGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGS 219

Query: 218 CSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIR--PVKDSELVY 275
           C+++TCWK +   + +   LK +Y ++ ++  +   T++ +  ++ D R  P+   +L+Y
Sbjct: 220 CAVKTCWKTMSSFEKIGHLLKDKYENSIQISDK---TKRKMRRREKDQRKIPIHKDDLLY 276

Query: 276 LQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHW 335
           +  SP++C++++K+G  GTQ R+CN+TS G+D C+L+CCGRGYN +  R VERC CK+ W
Sbjct: 277 VNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIW 336

Query: 336 CCYVTCRRCERTVERYVCK 354
           CCYV CRRCE   + + CK
Sbjct: 337 CCYVRCRRCESMTDVHTCK 355


>gi|17505193 wingless-type MMTV integration site family, member 7B
           precursor [Homo sapiens]
          Length = 349

 Score =  258 bits (658), Expect = 7e-69
 Identities = 128/343 (37%), Positives = 201/343 (58%), Gaps = 16/343 (4%)

Query: 21  VCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKAC 80
           +C+G+ ++ L    S +AL     C ++ GL   Q  +C+S  + +  +   A+  +  C
Sbjct: 14  LCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINEC 73

Query: 81  RRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSC 140
           +  F   RWNCS++     +  +L  G+RE+AF YA++AA ++HA+  AC+ G+L  C C
Sbjct: 74  QYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGC 133

Query: 141 GPVPGEPPG-----PGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSE 195
                E  G      G +WGGC+ ++ YG+    +F DA  ++KK    A +LM LHN+E
Sbjct: 134 DR---EKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDA-REIKKN---ARRLMNLHNNE 186

Query: 196 VGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKV-VHRPMGT 254
            GR+ L   ++++CKCHGVSGSC+ +TCW  L + ++V   LK +Y +A +V V R    
Sbjct: 187 AGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRL 246

Query: 255 RKHLVPKDLDIRPVK---DSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDL 311
           R+    +   +R  +   +++LVY++ SP++C ++   GS GTQ R CN+TS G+D CD 
Sbjct: 247 RQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDT 306

Query: 312 MCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
           MCCGRGYN +    V +C+CK+HWCC+V C  C    E + CK
Sbjct: 307 MCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK 349


>gi|17505191 wingless-type MMTV integration site family, member 7A
           precursor [Homo sapiens]
          Length = 349

 Score =  254 bits (650), Expect = 6e-68
 Identities = 128/342 (37%), Positives = 194/342 (56%), Gaps = 20/342 (5%)

Query: 24  GIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRA 83
           G+ +L +    S +AL  +  C ++ GL   Q  +C+S  + +  +   ++  +  C+  
Sbjct: 17  GMVYLRIGGFSSVVALGASIICNKIPGLAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQ 76

Query: 84  FADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPV 143
           F + RWNCS++     +  +L+ G+RE+AF YA+ AA ++HAI  ACT G+L  C C   
Sbjct: 77  FRNGRWNCSALGERTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDK- 135

Query: 144 PGEPPGP-----GNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGR 198
             E  G      G +WGGC+ ++ YG+     F DA    ++    A  LM LHN+E GR
Sbjct: 136 --EKQGQYHRDEGWKWGGCSADIRYGIGFAKVFVDA----REIKQNARTLMNLHNNEAGR 189

Query: 199 QALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHL 258
           + L  +++++CKCHGVSGSC+ +TCW  L + +++   LK +Y  A  V   P+   ++ 
Sbjct: 190 KILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHV--EPVRASRNK 247

Query: 259 VP------KDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLM 312
            P      K L  R   D++LVY++ SP++C ++   GS GTQ R CNKT+  +  CDLM
Sbjct: 248 RPTFLKIKKPLSYRKPMDTDLVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLM 307

Query: 313 CCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
           CCGRGYN +    V +C+CK+HWCCYV C  C    E Y CK
Sbjct: 308 CCGRGYNTHQYARVWQCNCKFHWCCYVKCNTCSERTEMYTCK 349


>gi|4885655 wingless-type MMTV integration site family, member 1
           precursor [Homo sapiens]
          Length = 370

 Score =  253 bits (645), Expect = 2e-67
 Identities = 117/313 (37%), Positives = 184/313 (58%), Gaps = 11/313 (3%)

Query: 48  LEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERG 107
           L+ L   Q +L R N  ++H+V    +  ++ C+  F + RWNC +      +   + RG
Sbjct: 61  LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG 120

Query: 108 TRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNLSYGLLM 167
            RE+AF++A+++A ++H++AR+C+ G +  C+C      P GP   WGGC+DN+ +G L 
Sbjct: 121 CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF 180

Query: 168 GAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGL 227
           G +F D+  K    G     LM LHN+E GR  + + +  +CKCHG+SGSC++RTCW  L
Sbjct: 181 GREFVDSGEK----GRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRL 236

Query: 228 QELQDVAADLKTRYLSATKVVHRPMGTRK-------HLVPKDLDIRPVKDSELVYLQSSP 280
             L+ V   L+ R+  A++V++   G+ +        L P+D   +P    +LVY + SP
Sbjct: 237 PTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSP 296

Query: 281 DFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVT 340
           +FC  + ++G+ GT  R CN +S   D C+L+CCGRG+   T RV ERC+C +HWCC+V+
Sbjct: 297 NFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVS 356

Query: 341 CRRCERTVERYVC 353
           CR C  T   + C
Sbjct: 357 CRNCTHTRVLHEC 369


>gi|4507927 wingless-type MMTV integration site family member 2
           precursor [Homo sapiens]
          Length = 360

 Score =  250 bits (638), Expect = 2e-66
 Identities = 124/314 (39%), Positives = 182/314 (57%), Gaps = 9/314 (2%)

Query: 45  CKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYL-LD 103
           C  + GLVS+Q QLC  + ++M  +     E    C+  F   RWNC++++   +     
Sbjct: 41  CDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRV 100

Query: 104 LERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPGEPPGPGNR---WGGCADN 160
           L R +RESAFVYA+S+A +  AI RAC+ G++  CSC P              WGGC+DN
Sbjct: 101 LLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCDPKKMGSAKDSKGIFDWGGCSDN 160

Query: 161 LSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSI 220
           + YG+     F DA    ++ G  A  LM LHN+  GR+A++  L+ +CKCHGVSGSC++
Sbjct: 161 IDYGIKFARAFVDAK---ERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTL 217

Query: 221 RTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSP 280
           RTCW  + + +     L  +Y  A +VV    GT    V  +   +P K+ +LVY ++SP
Sbjct: 218 RTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTG-FTVANERFKKPTKN-DLVYFENSP 275

Query: 281 DFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVT 340
           D+C+++ + GS GT  R CN TS G DSC++MCCGRGY+      + +C CK+HWCC V 
Sbjct: 276 DYCIRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVR 335

Query: 341 CRRCERTVERYVCK 354
           C+ C   ++ + CK
Sbjct: 336 CQDCLEALDVHTCK 349


>gi|16507239 wingless-type MMTV integration site family, member 6
           precursor [Homo sapiens]
          Length = 365

 Score =  239 bits (611), Expect = 2e-63
 Identities = 132/365 (36%), Positives = 196/365 (53%), Gaps = 34/365 (9%)

Query: 12  LFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVH 71
           L  L L      G  W A+    S L ++ T  C++   L   Q +LC++  E++  +  
Sbjct: 11  LLLLLLLCPAHVGGLWWAVG---SPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELAR 67

Query: 72  AAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACT 131
            AR  ++ C+  F   RWNCSS   A   +L  ++  RE+AFV+A++AA  SHA+ +AC+
Sbjct: 68  GARLGVRECQFQFRFRRWNCSSHSKAFGRIL--QQDIRETAFVFAITAAGASHAVTQACS 125

Query: 132 SGDLPGCSC-----------GPVPGEP--PGPGN--------RWGGCADNLSYGLLMGAK 170
            G+L  C C             +PG P  PGP           WGGC D++ +G      
Sbjct: 126 MGELLQCGCQAPRGRAPPRPSGLPGTPGPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRL 185

Query: 171 FSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQEL 230
           F DA  + K+       L++LHN+E GR A+R+    +CKCHG+SGSC++RTCW+ L   
Sbjct: 186 FMDA--RHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPF 243

Query: 231 QDVAADLKTRYLSATKVVHRPMGTR--KHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEK 288
           ++V A L  R+  A++V    MGT   K L+P    ++P   ++L+Y   SPDFC  N +
Sbjct: 244 REVGARLLERFHGASRV----MGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRR 299

Query: 289 VGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTV 348
            GS GT+ R CN ++     CDL+CCGRG+   + ++ E C C++HWCC V C RC    
Sbjct: 300 TGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRK 359

Query: 349 ERYVC 353
           E  +C
Sbjct: 360 ELSLC 364


>gi|16936522 wingless-type MMTV integration site family, member 10B
           precursor [Homo sapiens]
          Length = 389

 Score =  235 bits (599), Expect = 5e-62
 Identities = 132/365 (36%), Positives = 180/365 (49%), Gaps = 52/365 (14%)

Query: 32  KTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNC 91
           K P    L     C  L GL   Q+ LC  N ++  + +      +  C+    D RWNC
Sbjct: 35  KLPGEPPLTANTVCLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNC 94

Query: 92  SSIE---LAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCG------- 141
           S++E     P++   L+RG RESAF +++ AA + HA+A AC+ G L  C CG       
Sbjct: 95  SALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQ 154

Query: 142 -------------------------PVPGEPPGPGNR----WGGCADNLSYGLLMGAKFS 172
                                    P PG  P PG +    WGGC  ++ +    G KFS
Sbjct: 155 DRLRAKLLQLQALSRGKSFPHSLPSPGPGSSPSPGPQDTWEWGGCNHDMDF----GEKFS 210

Query: 173 DAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQD 232
              +  ++        MR+HN+ VGRQ +  +L+ KCKCHG SGSC  +TCW+   E + 
Sbjct: 211 RDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRA 270

Query: 233 VAADLKTRYLSATKV--VHRPMGT-RKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKV 289
           V A L+ R   A  +   +R  G  +  L P+ L        ELVY + SPDFC ++  +
Sbjct: 271 VGAALRERLGRAIFIDTHNRNSGAFQPRLRPRRL------SGELVYFEKSPDFCERDPTM 324

Query: 290 GSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVE 349
           GS GT+ R CNKTS   D C  +CCGRG+N      VERCHC++HWCCYV C  C+ T  
Sbjct: 325 GSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEW 384

Query: 350 RYVCK 354
             VCK
Sbjct: 385 VNVCK 389


>gi|16936520 wingless-type MMTV integration site family, member 10A
           precursor [Homo sapiens]
          Length = 417

 Score =  226 bits (577), Expect = 2e-59
 Identities = 134/395 (33%), Positives = 186/395 (47%), Gaps = 58/395 (14%)

Query: 11  LLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVV 70
           LL A A+       I  L L   P    LN    C  L GL   Q+++C  + ++  + +
Sbjct: 30  LLLAAAMPRSAPNDILDLRLPPEP---VLNANTVCLTLPGLSRRQMEVCVRHPDVAASAI 86

Query: 71  HAAREVMKACRRAFADMRWNCSSIELAPNYLLD---LERGTRESAFVYALSAAAISHAIA 127
              +  +  C+  F D RWNCSS+E       +     RG RESAF YA++AA + HA++
Sbjct: 87  QGIQIAIHECQHQFRDQRWNCSSLETRNKIPYESPIFSRGFRESAFAYAIAAAGVVHAVS 146

Query: 128 RACTSGDLPGCSCGP------------------------------VPGEPP----GPGNR 153
            AC  G L  C C                                VP  P      PG +
Sbjct: 147 NACALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQRGKGLSHGVPEHPALPTASPGLQ 206

Query: 154 ----WGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKC 209
               WGGC+ ++ +G      F D+    ++     +  MRLHN+ VGRQA+  ++  KC
Sbjct: 207 DSWEWGGCSPDMGFGERFSKDFLDS----REPHRDIHARMRLHNNRVGRQAVMENMRRKC 262

Query: 210 KCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKV-VHRPMGTRKHLVPKDLDI--- 265
           KCHG SGSC ++TCW+   E + V A L++R+  AT +  H   G +    P        
Sbjct: 263 KCHGTSGSCQLKTCWQVTPEFRTVGALLRSRFHRATLIRPHNRNGGQLEPGPAGAPSPAP 322

Query: 266 ------RPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYN 319
                 R    ++LVY + SPDFC +  ++ S GT  R CNK+S GSD C  MCCGRG+N
Sbjct: 323 GAPGPRRRASPADLVYFEKSPDFCEREPRLDSAGTVGRLCNKSSAGSDGCGSMCCGRGHN 382

Query: 320 PYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
                  ERCHC++HWCC+V C  C  T    VCK
Sbjct: 383 ILRQTRSERCHCRFHWCCFVVCEECRITEWVSVCK 417


>gi|17505195 wingless-type MMTV integration site family, member 8A
           [Homo sapiens]
          Length = 351

 Score =  207 bits (527), Expect = 1e-53
 Identities = 107/300 (35%), Positives = 163/300 (54%), Gaps = 19/300 (6%)

Query: 68  TVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIA 127
           +V   A+  ++ C+  FA  RWNC    L  +    L   TRE++F++A+S+A + + I 
Sbjct: 42  SVALGAQSGIEECKFQFAWERWNCPENALQLSTHNRLRSATRETSFIHAISSAGVMYIIT 101

Query: 128 RACTSGDLPGCSC-GPVPGEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQAN 186
           + C+ GD   C C G   G+  G G  WGGC+DN+ +G  +   F D+  K    G  A 
Sbjct: 102 KNCSMGDFENCGCDGSNNGKTGGHGWIWGGCSDNVEFGERISKLFVDSLEK----GKDAR 157

Query: 187 KLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATK 246
            LM LHN+  GR A+RA+++  CKCHG+SGSCSI+TCW  L E +++   LK +Y  A K
Sbjct: 158 ALMNLHNNRAGRLAVRATMKRTCKCHGISGSCSIQTCWLQLAEFREMGDYLKAKYDQALK 217

Query: 247 V------VHRPMGTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCN 300
           +      +        H VP +  + P  ++EL++L+ SPD+C  N  +G +GT+ R+C 
Sbjct: 218 IEMDKRQLRAGNSAEGHWVPAEAFL-PSAEAELIFLEESPDYCTCNSSLGIYGTEGRECL 276

Query: 301 KTSNGSD-----SCDLMC--CGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVC 353
           + S+ +      SC  +C  CG         V+  C+CK+ WCC V C +C   V +Y C
Sbjct: 277 QNSHNTSRWERRSCGRLCTECGLQVEERKTEVISSCNCKFQWCCTVKCDQCRHVVSKYYC 336


>gi|110735437 wingless-type MMTV integration site family, member 8B
           precursor [Homo sapiens]
          Length = 351

 Score =  206 bits (523), Expect = 3e-53
 Identities = 108/297 (36%), Positives = 159/297 (53%), Gaps = 16/297 (5%)

Query: 68  TVVHAAREVMKACRRAFADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIA 127
           +V   A+  ++ C+  FA  RWNC    L  +    L    RE+AFV+A+S+A + + + 
Sbjct: 42  SVAAGAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLT 101

Query: 128 RACTSGDLPGCSCGPVP-GEPPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQAN 186
           R C+ GD   C C     G+  G G  WGGC+DN+ +G  +  +F DA     +TG  A 
Sbjct: 102 RNCSLGDFDNCGCDDSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDA----LETGQDAR 157

Query: 187 KLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATK 246
             M LHN+E GR+A++ +++  CKCHGVSGSC+ +TCW  L E ++V A LK +Y +A K
Sbjct: 158 AAMNLHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALK 217

Query: 247 VVHRPMGTRKHLVPKDL---DIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTS 303
            V    G       +       R +   ELV+L+ SPD+C++N+ +G  GT+ R+C +  
Sbjct: 218 -VDLLQGAGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRG 276

Query: 304 NG-----SDSCDLMC--CGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVC 353
                    SC  +C  CG          V  C+CK+HWCC V C +C R V +Y C
Sbjct: 277 RALGRWERRSCRRLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFC 333


>gi|17017976 wingless-type MMTV integration site family, member 9B
           precursor [Homo sapiens]
          Length = 357

 Score =  205 bits (522), Expect = 4e-53
 Identities = 120/323 (37%), Positives = 172/323 (53%), Gaps = 29/323 (8%)

Query: 44  HCKQLE--GLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADMRWNCSSIELAPNYL 101
           H KQ +   L   Q QLCR    L  T+  AA   +  C+  F   RWNCS        +
Sbjct: 51  HLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCS----LEGRM 106

Query: 102 LDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPGEPPGPGNRWGGCADNL 161
             L+RG +E+AF+YA+S+AA++H +ARAC++G +  C+C   PG       +WG C DNL
Sbjct: 107 GLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNL 166

Query: 162 SYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIR 221
            Y     + F  +    K   ++A+     HN+ VG +A+++ L   CKCHGVSGSC++R
Sbjct: 167 KYSTKFLSNFLGSKRGNKDLRARADA----HNTHVGIKAVKSGLRTTCKCHGVSGSCAVR 222

Query: 222 TCWKGLQELQDVAADLKTRYLSATKV---VHRPMG-------TRKHLVPKDLDIRPVKDS 271
           TCWK L   ++    LK RY SA KV    +  +G        R+  + K L  R     
Sbjct: 223 TCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPR---SG 279

Query: 272 ELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHC 331
           +LVY++ SP FC  ++   S GT  R C++ +    SC  +CCGRGY+  +  V   CHC
Sbjct: 280 DLVYMEDSPSFCRPSKY--SPGTAGRVCSREA----SCSSLCCGRGYDTQSRLVAFSCHC 333

Query: 332 KYHWCCYVTCRRCERTVERYVCK 354
           +  WCCYV C++C +    Y CK
Sbjct: 334 QVQWCCYVECQQCVQEELVYTCK 356


>gi|15082261 wingless-type MMTV integration site family, member 9A
           [Homo sapiens]
          Length = 365

 Score =  204 bits (518), Expect = 1e-52
 Identities = 118/339 (34%), Positives = 175/339 (51%), Gaps = 28/339 (8%)

Query: 28  LALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAFADM 87
           L L+  P A A    + C +L+ L   Q ++CR +  +  T+V A       C+  F   
Sbjct: 42  LPLTLEPEAAAQAHYKACDRLK-LERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFE 100

Query: 88  RWNCSSIELAPNYLLDL-ERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVPGE 146
           RWNC+   L   Y   L +RG +E+AF+YA+S+A ++HA+A+AC++G +  C+C   P  
Sbjct: 101 RWNCT---LEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDL 157

Query: 147 PPGPGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLE 206
                 +WGGC DNL Y      +F       +++       +  HN+ VG + ++A +E
Sbjct: 158 ENREAWQWGGCGDNLKYSSKFVKEFLG-----RRSSKDLRARVDFHNNLVGVKVIKAGVE 212

Query: 207 MKCKCHGVSGSCSIRTCWKGLQELQDVAADLKTRYLSATKV---VHRPMGTRKHLVPK-- 261
             CKCHGVSGSC++RTCW+ L    +V   LK +Y +A KV    +   G    + P   
Sbjct: 213 TTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRG 272

Query: 262 ------DLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCG 315
                   D  P +  ELV+L  SP FC+      S GT  R+C++  N    C+ +CCG
Sbjct: 273 RASGAGGSDPLP-RTPELVHLDDSPSFCLAGR--FSPGTAGRRCHREKN----CESICCG 325

Query: 316 RGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYVCK 354
           RG+N  +  V   C C+  WCCYV CR+C +  E Y CK
Sbjct: 326 RGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCK 364


>gi|239752226 PREDICTED: hypothetical protein XP_002348164 [Homo
           sapiens]
          Length = 661

 Score =  107 bits (268), Expect = 1e-23
 Identities = 63/194 (32%), Positives = 101/194 (52%), Gaps = 15/194 (7%)

Query: 25  IKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAAREVMKACRRAF 84
           + W       S +AL     C ++ GL   Q  +C+S  + +  +   A+  +  C+  F
Sbjct: 17  LSWRGRPALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQMGINECQYQF 76

Query: 85  ADMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHAIARACTSGDLPGCSCGPVP 144
              RWNCS++     +  +L  G+RE+AF YA++AA ++HA+  AC+ G+L  C C    
Sbjct: 77  RFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCGC---D 133

Query: 145 GEPPG-----PGNRWGGCADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQ 199
            E  G      G +WGGC+ ++ YG+    +F DA  ++KK    A +LM LHN+E GR+
Sbjct: 134 REKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDA-REIKK---NARRLMNLHNNEAGRK 189

Query: 200 ALRASLEMKCKCHG 213
             + SL    +C G
Sbjct: 190 QKQLSLR---RCAG 200


>gi|13562088 leucine-rich repeat-containing 3 precursor [Homo
           sapiens]
          Length = 257

 Score = 35.4 bits (80), Expect = 0.078
 Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 1/59 (1%)

Query: 201 LRASLEMKCKCHGVSGSCSIRTCWKGLQEL-QDVAADLKTRYLSATKVVHRPMGTRKHL 258
           L A+    C+C   +G+ ++    +GLQE+ +D+ A+     L A K+ H P G  +HL
Sbjct: 29  LGAACPQPCRCPDHAGAVAVFCSLRGLQEVPEDIPANTVLLKLDANKISHLPDGAFQHL 87


>gi|41327730 calponin 2 isoform b [Homo sapiens]
          Length = 270

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 253 GTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCD 310
           GTR+HL      I P  D   + LQ   + C     + + GT+ R    T  G+D CD
Sbjct: 146 GTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTR-RHIYDTKLGTDKCD 202


>gi|4758018 calponin 2 isoform a [Homo sapiens]
          Length = 309

 Score = 32.0 bits (71), Expect = 0.86
 Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 253 GTRKHLVPKDLDIRPVKDSELVYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCD 310
           GTR+HL      I P  D   + LQ   + C     + + GT+ R    T  G+D CD
Sbjct: 185 GTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTR-RHIYDTKLGTDKCD 241


>gi|12751479 zinc finger protein 643 [Homo sapiens]
          Length = 432

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 42/195 (21%), Positives = 68/195 (34%), Gaps = 35/195 (17%)

Query: 173 DAPMKVKKTG---SQANKLM---RLHNSEVGRQALR--------ASLEMKCKCHGVSGSC 218
           + P + K+ G   SQ++ L+   R+H  E   +           +SL    + H      
Sbjct: 202 EKPFRCKECGKAFSQSSSLIPHQRIHTGEKPYECKECGKTFRHPSSLTQHVRIHTGEKPY 261

Query: 219 SIRTCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLVPKDLDIRPVKDSELVYLQS 278
             R C K   +   +   L+T       V  +P  T K        IR ++  E+++   
Sbjct: 262 ECRVCEKAFSQSIGLIQHLRTH------VREKPF-TCKDCGKAFFQIRHLRQHEIIHTGV 314

Query: 279 SPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCY 338
            P  C    K  SH T   Q  +T  G        CG+ ++       +R H   H    
Sbjct: 315 KPYICNVCSKTFSHSTYLTQHQRTHTGERPYKCKECGKAFS-------QRIHLSIH---- 363

Query: 339 VTCRRCERTVERYVC 353
              +R    V+ Y C
Sbjct: 364 ---QRVHTGVKPYEC 375


>gi|73747887 ADAM metallopeptidase domain 12 isoform 2 preproprotein
           [Homo sapiens]
          Length = 738

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 5/41 (12%)

Query: 296 DRQCNKTSN-GSDSCDLMCCGRGYNPYTDRVVERCHCKYHW 335
           +RQC   S  G   C + C GRG     +R  + CHC+ HW
Sbjct: 646 NRQCQNISVFGVHECAMQCHGRGV--CNNR--KNCHCEAHW 682


>gi|73747885 ADAM metallopeptidase domain 12 isoform 1 preproprotein
           [Homo sapiens]
          Length = 909

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 5/41 (12%)

Query: 296 DRQCNKTSN-GSDSCDLMCCGRGYNPYTDRVVERCHCKYHW 335
           +RQC   S  G   C + C GRG     +R  + CHC+ HW
Sbjct: 646 NRQCQNISVFGVHECAMQCHGRGV--CNNR--KNCHCEAHW 682


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 29.6 bits (65), Expect = 4.3
 Identities = 14/43 (32%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 296  DRQCNKTSNGSDSCDLMCCG--RGYNPYTDRVVERCHCK-YHW 335
            D+QC +   GS +C    C   +G++P  ++   +CHCK +H+
Sbjct: 2024 DQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHY 2066


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.134    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,466,112
Number of Sequences: 37866
Number of extensions: 680357
Number of successful extensions: 2634
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2529
Number of HSP's gapped (non-prelim): 52
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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