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Search of human proteins with 169790825
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
(2769 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 5740 0.0
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 3889 0.0
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens] 3686 0.0
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens] 3680 0.0
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 3668 0.0
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 3650 0.0
gi|153946395 tenascin C precursor [Homo sapiens] 223 2e-57
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 220 1e-56
gi|24041035 notch 2 preproprotein [Homo sapiens] 147 1e-34
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 139 3e-32
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 139 5e-32
gi|4557679 jagged 1 precursor [Homo sapiens] 139 5e-32
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 137 1e-31
gi|148833508 notch1 preproprotein [Homo sapiens] 137 1e-31
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 135 4e-31
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 133 2e-30
gi|55770876 notch4 preproprotein [Homo sapiens] 133 2e-30
gi|134244285 Notch homolog 3 [Homo sapiens] 131 8e-30
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 131 8e-30
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 131 1e-29
gi|157384973 tenascin R [Homo sapiens] 130 2e-29
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 129 5e-29
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 127 1e-28
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 127 2e-28
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 127 2e-28
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 120 2e-26
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 120 2e-26
gi|122937283 6720455I24Rik homolog [Homo sapiens] 120 2e-26
gi|110735443 delta-like 1 [Homo sapiens] 118 7e-26
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 118 7e-26
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 5740 bits (14891), Expect = 0.0
Identities = 2769/2769 (100%), Positives = 2769/2769 (100%)
Query: 1 MDVKERKPYRSLTRRRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSRV 60
MDVKERKPYRSLTRRRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSRV
Sbjct: 1 MDVKERKPYRSLTRRRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSRV 60
Query: 61 KDIVPQEAEEFCRTGANFTLRELGLEEVTPPHGTLYRTDIGLPHCGYSMGAGSDADMEAD 120
KDIVPQEAEEFCRTGANFTLRELGLEEVTPPHGTLYRTDIGLPHCGYSMGAGSDADMEAD
Sbjct: 61 KDIVPQEAEEFCRTGANFTLRELGLEEVTPPHGTLYRTDIGLPHCGYSMGAGSDADMEAD 120
Query: 121 TVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQNHARLRTPP 180
TVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQNHARLRTPP
Sbjct: 121 TVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQNHARLRTPP 180
Query: 181 PPLSHAHTPNQHHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGGAQEPAHAQENWL 240
PPLSHAHTPNQHHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGGAQEPAHAQENWL
Sbjct: 181 PPLSHAHTPNQHHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGGAQEPAHAQENWL 240
Query: 241 LNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHFLFKPGGTSPLFCTTS 300
LNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHFLFKPGGTSPLFCTTS
Sbjct: 241 LNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHFLFKPGGTSPLFCTTS 300
Query: 301 PGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAALSAIVISATLVILLAYF 360
PGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAALSAIVISATLVILLAYF
Sbjct: 301 PGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAALSAIVISATLVILLAYF 360
Query: 361 VAMHLFGLNWHLQPMEGQMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGTTEGK 420
VAMHLFGLNWHLQPMEGQMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGTTEGK
Sbjct: 361 VAMHLFGLNWHLQPMEGQMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKGKGTTEGK 420
Query: 421 PSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYG 480
PSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYG
Sbjct: 421 PSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKAALVGIYG 480
Query: 481 RKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQYLDSGIWH 540
RKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQYLDSGIWH
Sbjct: 481 RKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQYLDSGIWH 540
Query: 541 LAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVL 600
LAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVL
Sbjct: 541 LAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVL 600
Query: 601 CSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV 660
CSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV
Sbjct: 601 CSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV 660
Query: 661 DCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWT 720
DCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWT
Sbjct: 661 DCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWT 720
Query: 721 GHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPG 780
GHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPG
Sbjct: 721 GHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPG 780
Query: 781 WNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGD 840
WNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGD
Sbjct: 781 WNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGD 840
Query: 841 SKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQVPVSQQNLHSFYDRIKF 900
SKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQVPVSQQNLHSFYDRIKF
Sbjct: 841 SKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQVPVSQQNLHSFYDRIKF 900
Query: 901 LVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFVNNPLFGYTISRQDGSF 960
LVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFVNNPLFGYTISRQDGSF
Sbjct: 901 LVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFVNNPLFGYTISRQDGSF 960
Query: 961 DLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENEIPSCDLSNFARPN 1020
DLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENEIPSCDLSNFARPN
Sbjct: 961 DLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENEIPSCDLSNFARPN 1020
Query: 1021 PVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYLSSRTPGYKSVLRISLT 1080
PVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYLSSRTPGYKSVLRISLT
Sbjct: 1021 PVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYLSSRTPGYKSVLRISLT 1080
Query: 1081 HPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGY 1140
HPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGY
Sbjct: 1081 HPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSEAFVSVGY 1140
Query: 1141 EYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVSQQP 1200
EYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVSQQP
Sbjct: 1141 EYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGENQFVSQQP 1200
Query: 1201 PVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNV 1260
PVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNV
Sbjct: 1201 PVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRRIFPSGNV 1260
Query: 1261 TNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEV 1320
TNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEV
Sbjct: 1261 TNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEV 1320
Query: 1321 VAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRIDQNGIIST 1380
VAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRIDQNGIIST
Sbjct: 1321 VAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRIDQNGIIST 1380
Query: 1381 LLGSNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRI 1440
LLGSNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRI
Sbjct: 1381 LLGSNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVLQISENHQVRI 1440
Query: 1441 VAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTS 1500
VAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTS
Sbjct: 1441 VAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINRIRQVTTS 1500
Query: 1501 GEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRI 1560
GEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRI
Sbjct: 1501 GEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVADLGNIRI 1560
Query: 1561 RFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNFTYTGDGDITL 1620
RFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNFTYTGDGDITL
Sbjct: 1561 RFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNFTYTGDGDITL 1620
Query: 1621 ITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSG 1680
ITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSG
Sbjct: 1621 ITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQGHELAMMTYHGNSG 1680
Query: 1681 LLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKDDVTITT 1740
LLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKDDVTITT
Sbjct: 1681 LLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSKDDVTITT 1740
Query: 1741 NLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNV 1800
NLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNV
Sbjct: 1741 NLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLLAGTVNPTVGKRNV 1800
Query: 1801 TLPIDNGLNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFT 1860
TLPIDNGLNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFT
Sbjct: 1801 TLPIDNGLNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFT 1860
Query: 1861 LRILYDQAGRPSLWSPSSRLNGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFAD 1920
LRILYDQAGRPSLWSPSSRLNGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFAD
Sbjct: 1861 LRILYDQAGRPSLWSPSSRLNGVNVTYSPGGYIAGIQRGIMSERMEYDQAGRITSRIFAD 1920
Query: 1921 GKTWSYTYLEKSMVLLLHSQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQ 1980
GKTWSYTYLEKSMVLLLHSQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQ
Sbjct: 1921 GKTWSYTYLEKSMVLLLHSQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSVGYYRNIYQ 1980
Query: 1981 PPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGM 2040
PPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGM
Sbjct: 1981 PPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSFTYDETAGM 2040
Query: 2041 LKTINLQNEGFTCTIRYRQIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVINE 2100
LKTINLQNEGFTCTIRYRQIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVINE
Sbjct: 2041 LKTINLQNEGFTCTIRYRQIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVTSMQAVINE 2100
Query: 2101 TPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMTHTKHFDAYGRMKEVQYEIFR 2160
TPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMTHTKHFDAYGRMKEVQYEIFR
Sbjct: 2101 TPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMTHTKHFDAYGRMKEVQYEIFR 2160
Query: 2161 SLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLN 2220
SLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLN
Sbjct: 2161 SLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPLWRYSYDLN 2220
Query: 2221 GNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKA 2280
GNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKA
Sbjct: 2221 GNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKA 2280
Query: 2281 YNRAGSWSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYD 2340
YNRAGSWSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYD
Sbjct: 2281 YNRAGSWSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSSEITSLYYD 2340
Query: 2341 LQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIII 2400
LQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIII
Sbjct: 2341 LQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDTNPNFQIII 2400
Query: 2401 GYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNLYMFKNNNPISN 2460
GYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNLYMFKNNNPISN
Sbjct: 2401 GYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNLYMFKNNNPISN 2460
Query: 2461 SQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSIL 2520
SQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSIL
Sbjct: 2461 SQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQEWDNSKSIL 2520
Query: 2521 GVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKKFASSGSVFGKGVKFALKDGRVT 2580
GVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKKFASSGSVFGKGVKFALKDGRVT
Sbjct: 2521 GVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKKFASSGSVFGKGVKFALKDGRVT 2580
Query: 2581 TDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRT 2640
TDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRT
Sbjct: 2581 TDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAILGLSGGRRT 2640
Query: 2641 LENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVR 2700
LENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVR
Sbjct: 2641 LENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLELARQRAVR 2700
Query: 2701 QAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHF 2760
QAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHF
Sbjct: 2701 QAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELSDSANNIHF 2760
Query: 2761 MRQSEMGRR 2769
MRQSEMGRR
Sbjct: 2761 MRQSEMGRR 2769
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 3889 bits (10085), Expect = 0.0
Identities = 1861/2777 (67%), Positives = 2218/2777 (79%), Gaps = 86/2777 (3%)
Query: 1 MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAP-QKSYSSSETLKAYDQDA-RLAYG 57
MDVKER+PY SLT+ RR+ ERRYT+SSAD+EE + P QKSYSSSETLKA+D D+ RL YG
Sbjct: 1 MDVKERRPYCSLTKSRREKERRYTNSSADNEECRVPTQKSYSSSETLKAFDHDSSRLLYG 60
Query: 58 SRVKDIVPQEAEEFCRTGANFTLRELGLEEVTPPHGTLYRTDIGLPHCGYSMGAGSDADM 117
+RVKD+V +EA+EF R G NFTLR+LG+ E G + ++GLPH GYS+ AGSDAD
Sbjct: 61 NRVKDLVHREADEFTRQGQNFTLRQLGVCEPATRRGLAFCAEMGLPHRGYSISAGSDADT 120
Query: 118 EADTVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHEN---TETDHPGGLQNHA 174
E + V+SPEH +RLWGR +SGRSSCLSSR+NS LTLTDTEHEN +E + P Q +
Sbjct: 121 ENEAVMSPEHAMRLWGRGVKSGRSSCLSSRSNSALTLTDTEHENKSDSENEQPASNQGQS 180
Query: 175 RLRTPPPPLSHAHTPNQHHAASINSLNRGNFTPRSNPSPAPTDHSLSGEPPAGGAQEPAH 234
L+ PP SH QHH SI SLNR + T R N SPAP +L E E
Sbjct: 181 TLQPLPP--SHKQHSAQHHP-SITSLNRNSLTNRRNQSPAPPA-ALPAELQT--TPESVQ 234
Query: 235 AQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHFLFKPG-GTS 293
Q++W+L SN+PLE+R HFLFK G GT+
Sbjct: 235 LQDSWVLGSNVPLESR---------------------------------HFLFKTGTGTT 261
Query: 294 PLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAALSAIVISATL 353
PLF T +PGY + S +VYSPP RPLPR+T +R AF KK SKYC+WKC AL A+ +S L
Sbjct: 262 PLFSTATPGYTMASGSVYSPPTRPLPRNTLSRSAFKFKKSSKYCSWKCTALCAVGVSVLL 321
Query: 354 VILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTASSWPVPTDVSLYPSGGTGLETPDRKG 413
ILL+YF+AMHLFGLNW LQ E +E +S +PT+ PSG G
Sbjct: 322 AILLSYFIAMHLFGLNWQLQQTENDTFE--NGKVNSDTMPTNTVSLPSGDNG-------- 371
Query: 414 KGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHLKFNVSLGKA 473
K F E++ IDSGE+D+GRRA Q+IPPG FWRSQ+FID P LKFN+SL K
Sbjct: 372 ------KLGGFTQENNTIDSGELDIGRRAIQEIPPGIFWRSQLFIDQPQFLKFNISLQKD 425
Query: 474 ALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQY 533
AL+G+YGRKGLPPSHTQ+DFVELLDG RL+ +E RSL T R R S HE GFIQY
Sbjct: 426 ALIGVYGRKGLPPSHTQYDFVELLDGSRLIAREQRSLLETERAGRQARSVSLHEAGFIQY 485
Query: 534 LDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCG 593
LDSGIWHLAFYNDGK +E VSF T IESV CP NC+GNG+C+SGTCHCF GFLGPDC
Sbjct: 486 LDSGIWHLAFYNDGKNAEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCS 545
Query: 594 RASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYK 653
RA+CPVLCSGNGQY KGRCLC SGWKG ECDVPT QCID C G CI G+C CN GYK
Sbjct: 546 RAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGSCACNSGYK 605
Query: 654 GESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLC 713
GESCEE DC+DP CS GVC+ GECHCS GWGG+NCE + C DQCSGHGT+L ++G C
Sbjct: 606 GESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSC 665
Query: 714 SCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDG 773
+CDP+WTG DCS EIC+ DCG HGVC+GGTCRCE+GW G AC+QRACHPRCAEHGTC+DG
Sbjct: 666 TCDPNWTGPDCSNEICSVDCGSHGVCMGGTCRCEEGWTGPACNQRACHPRCAEHGTCKDG 725
Query: 774 KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTS 833
KCECS GWNGEHCTI EGCPGLCN NGRCTLD NGWHCVCQ GWRGAGCD +
Sbjct: 726 KCECSQGWNGEHCTI---------EGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVA 776
Query: 834 METACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQVPVSQQNLHS 893
MET C DSKDN+GDGL+DCMDPDCCLQ C P C G P+P DII ++ SQQ S
Sbjct: 777 METLCTDSKDNEGDGLIDCMDPDCCLQSSCQNQPYCRGLPDPQDIISQSLQSPSQQAAKS 836
Query: 894 FYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFVNNPLFGYTI 953
FYDRI FL+G DSTH+IPGE+PF+ A VIRGQV+T+DGTPL+GVN+SF + P +GYTI
Sbjct: 837 FYDRISFLIGSDSTHVIPGESPFNKSLASVIRGQVLTADGTPLIGVNVSFFHYPEYGYTI 896
Query: 954 SRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHEENEIPSCDL 1013
+RQDG FDLV NGG S+ L FER+PF+TQ HT+W+PW+ F+VM+T++M+ EEN+IPSCDL
Sbjct: 897 TRQDGMFDLVANGGASLTLVFERSPFLTQYHTVWIPWNVFYVMDTLVMKKEENDIPSCDL 956
Query: 1014 SNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYLSSRTPGYKS 1073
S F RPNP++ SPL++F S E PI+PE Q L EE +I G ++LSYLSSR GYKS
Sbjct: 957 SGFVRPNPIIVSSPLSTFFRSSPEDSPIIPETQVLHEETTIPGTDLKLSYLSSRAAGYKS 1016
Query: 1074 VLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVYNQKVFGLSE 1133
VL+I++T IPFNLMKVHLMVAV GRLF+KWF A+P+L+Y FIWDKTD YNQKV+GLSE
Sbjct: 1017 VLKITMTQSIIPFNLMKVHLMVAVVGRLFQKWFPASPNLAYTFIWDKTDAYNQKVYGLSE 1076
Query: 1134 AFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSGILHKGNGEN 1193
A VSVGYEYESC DL LWEKRT +LQGYE+DAS +GGW+LDKHH L++Q+GIL+KGNGEN
Sbjct: 1077 AVVSVGYEYESCLDLTLWEKRTAILQGYELDASNMGGWTLDKHHVLDVQNGILYKGNGEN 1136
Query: 1194 QFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLYVGDFNYIRR 1253
QF+SQQPPV+ SIMGNGRRRSISCPSCNG ADGNKLLAPVAL CG DGSLYVGDFNY+RR
Sbjct: 1137 QFISQQPPVVSSIMGNGRRRSISCPSCNGQADGNKLLAPVALACGIDGSLYVGDFNYVRR 1196
Query: 1254 IFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFKIKSTVVVKD 1313
IFPSGNVT++LEL S +PAH+YYLATDP++G +++SD+N+RR+++ KS KD
Sbjct: 1197 IFPSGNVTSVLEL-------SSNPAHRYYLATDPVTGDLYVSDTNTRRIYRPKSLTGAKD 1249
Query: 1314 LVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFVDGTMIRRID 1373
L KN+EVVAGTG+QCLPFD+ RCGDGGKA EATL +P+G+ VDK GLIYFVDGTMIR++D
Sbjct: 1250 LTKNAEVVAGTGEQCLPFDEARCGDGGKAVEATLMSPKGMAVDKNGLIYFVDGTMIRKVD 1309
Query: 1374 QNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVLDNNVVLQIS 1433
QNGIISTLLGSNDLTSARPL+CD+ M ISQV LEWPTDLAINPMDNS+YVLDNNVVLQI+
Sbjct: 1310 QNGIISTLLGSNDLTSARPLTCDTSMHISQVRLEWPTDLAINPMDNSIYVLDNNVVLQIT 1369
Query: 1434 ENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIAETDEKKINR 1493
EN QVRI AGRPMHCQVPG++ + + K A+ TLESATA+AVS++GVLYI ETDEKKINR
Sbjct: 1370 ENRQVRIAAGRPMHCQVPGVE-YPVGKHAVQTTLESATAIAVSYSGVLYITETDEKKINR 1428
Query: 1494 IRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAVCADGELYVA 1553
IRQVTT GEISLVAG PS CDCKNDANCDC+ DGYAKDAKL+ PSSLA DG LY+A
Sbjct: 1429 IRQVTTDGEISLVAGIPSECDCKNDANCDCYQSGDGYAKDAKLSAPSSLAASPDGTLYIA 1488
Query: 1554 DLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTGDYLYNFTYT 1613
DLGNIRIR + KNKP LN+ N YE++SP DQELY+FD G H YT SL TGDYLYNF+Y+
Sbjct: 1489 DLGNIRIRAVSKNKPLLNSMNFYEVASPTDQELYIFDINGTHQYTVSLVTGDYLYNFSYS 1548
Query: 1614 GDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVTTQGHELAMM 1673
D DIT +TD+NGN + +RRD MP+ +V PD QV W+T+GTN LKS+T QG EL +
Sbjct: 1549 NDNDITAVTDSNGNTLRIRRDPNRMPVRVVSPDNQVIWLTIGTNGCLKSMTAQGLELVLF 1608
Query: 1674 TYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSVHVQVETSSK 1733
TYHGNSGLLATKS+E GWTTF++YDS GRLTNVTFPTG V++ D D ++ V +E+SS+
Sbjct: 1609 TYHGNSGLLATKSDETGWTTFFDYDSEGRLTNVTFPTGVVTNLHGDMDKAITVDIESSSR 1668
Query: 1734 D-DVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTEPHLLAGTVN 1792
+ DV+IT+NLS+ +FYT++QDQ+RNSY IG DGSLR++ A+G++ QTEPH+LAGT N
Sbjct: 1669 EEDVSITSNLSSIDSFYTMVQDQLRNSYQIGYDGSLRIIYASGLDSHYQTEPHVLAGTAN 1728
Query: 1793 PTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDFDRVTRTEKI 1852
PTV KRN+TLP +NG NLVEWR RKEQA+G+V VFGR+LRV+ RNLLS+DFDR T+TEKI
Sbjct: 1729 PTVAKRNMTLPGENGQNLVEWRFRKEQAQGKVNVFGRKLRVNGRNLLSVDFDRTTKTEKI 1788
Query: 1853 YDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYSPGGYIAGIQRGIMSERMEYDQAGR 1912
YDDHRKF LRI YD +G P+LW PSS+L VNVTYS G IA IQRG SE+++YD GR
Sbjct: 1789 YDDHRKFLLRIAYDTSGHPTLWLPSSKLMAVNVTYSSTGQIASIQRGTTSEKVDYDGQGR 1848
Query: 1913 ITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFDKNDRLSSVTMPNVARQTLETIRSV 1972
I SR+FADGKTWSYTYLEKSMVLLLHSQRQYIFE+D DRLS++TMP+VAR T++TIRS+
Sbjct: 1849 IVSRVFADGKTWSYTYLEKSMVLLLHSQRQYIFEYDMWDRLSAITMPSVARHTMQTIRSI 1908
Query: 1973 GYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAETLYDTTKVSF 2032
GYYRNIY PPE NAS+I D+ E+G LL T +LGT RRV++KY + ++L+E LYD+T+VSF
Sbjct: 1909 GYYRNIYNPPESNASIITDYNEEGLLLQTAFLGTSRRVLFKYRRQTRLSEILYDSTRVSF 1968
Query: 2033 TYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQIFRFTEEGMVNARFDYNYDNSFRVT 2092
TYDETAG+LKT+NLQ++GF CTIRYRQIGPLIDRQIFRF+E+GMVNARFDY+YDNSFRVT
Sbjct: 1969 TYDETAGVLKTVNLQSDGFICTIRYRQIGPLIDRQIFRFSEDGMVNARFDYSYDNSFRVT 2028
Query: 2093 SMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMTHTKHFDAYGRMK 2152
SMQ VINETPLPIDLY++DD+SGK EQFGKFGVIYYDINQII+TAVMT+TKHFDA+GR+K
Sbjct: 2029 SMQGVINETPLPIDLYQFDDISGKVEQFGKFGVIYYDINQIISTAVMTYTKHFDAHGRIK 2088
Query: 2153 EVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQLQTVSINDKPL 2212
E+QYEIFRSLMYW+T+QYDNMGRV K+E+K+GP+ANTT+Y+YEYD DGQLQTV +N+K +
Sbjct: 2089 EIQYEIFRSLMYWITIQYDNMGRVTKREIKIGPFANTTKYAYEYDVDGQLQTVYLNEKIM 2148
Query: 2213 WRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYKMDEDGFLRQRGGDIFEYN 2272
WRY+YDLNGNLHLL+P NSARLTPLRYD+RDRITRLGDVQY++DEDGFLRQRG +IFEY+
Sbjct: 2149 WRYNYDLNGNLHLLNPSNSARLTPLRYDLRDRITRLGDVQYRLDEDGFLRQRGTEIFEYS 2208
Query: 2273 SAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTKVTHLYNHSSS 2332
S GLL + Y++ W+V YRYDGLGRRVSSK+S HLQFFYADLT PT++TH+YNHSSS
Sbjct: 2209 SKGLLTRVYSKGSGWTVIYRYDGLGRRVSSKTSLGQHLQFFYADLTYPTRITHVYNHSSS 2268
Query: 2333 EITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILYTAYGEIYMDT 2392
EITSLYYDLQGHLFAME+SSGDEFYIA DN GTPLAVFS GLM+KQI YTAYGEIY D+
Sbjct: 2269 EITSLYYDLQGHLFAMEISSGDEFYIASDNTGTPLAVFSSNGLMLKQIQYTAYGEIYFDS 2328
Query: 2393 NPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSSNVMPFNLYMF 2452
N +FQ++IG+HGGLYDPLTKL+H G RDYD+LAGRWT+PD E+WK + + PFNLYMF
Sbjct: 2329 NIDFQLVIGFHGGLYDPLTKLIHFGERDYDILAGRWTTPDIEIWKRI-GKDPAPFNLYMF 2387
Query: 2453 KNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYELIHTQMKTQE 2512
+NNNP S D+K ++TDVNSWL+TFGF LHN IPG+P P D EPSYEL+ K+Q+
Sbjct: 2388 RNNNPASKIHDVKDYITDVNSWLVTFGFHLHNAIPGFPVPKFDLTEPSYELV----KSQQ 2443
Query: 2513 WDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKKFASSGSVFGKGVKF 2572
WD+ I GVQ +V +Q KAF++L + ++ S A FA+ S+ GKGV
Sbjct: 2444 WDDIPPIFGVQQQVARQAKAFLSLGKMAEVQVSR-RRAGGAQSWLWFATVKSLIGKGVML 2502
Query: 2573 ALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHYFVKPGPSEGDLAIL 2632
A+ GRV T+++++ANED +VAA+LN+A YLENLHFTI+G DTHYF+K E DL L
Sbjct: 2503 AVSQGRVQTNVLNIANEDCIKVAAVLNNAFYLENLHFTIEGKDTHYFIKTTTPESDLGTL 2562
Query: 2633 GLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTRYGTTLDEEKARVLE 2692
L+ GR+ LENG+NVTVSQ TV+NGRTRR+ D+++Q+GAL L+ RYG TLDEEKAR+LE
Sbjct: 2563 RLTSGRKALENGINVTVSQSTTVVNGRTRRFADVEMQFGALALHVRYGMTLDEEKARILE 2622
Query: 2693 LARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQGYDGFFVISVEQYPELS 2752
ARQRA+ +AWAREQQR+R+GEEG R WTEGEK+Q+LS G+VQGYDG++V+SVEQYPEL+
Sbjct: 2623 QARQRALARAWAREQQRVRDGEEGARLWTEGEKRQLLSAGKVQGYDGYYVLSVEQYPELA 2682
Query: 2753 DSANNIHFMRQSEMGRR 2769
DSANNI F+RQSE+GRR
Sbjct: 2683 DSANNIQFLRQSEIGRR 2699
>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
Length = 2732
Score = 3686 bits (9559), Expect = 0.0
Identities = 1753/2801 (62%), Positives = 2156/2801 (76%), Gaps = 101/2801 (3%)
Query: 1 MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSR 59
M+ + KPY+ L + + + + YTSSS +SE+G+ P++SY+S ETL Y+Q+ R+ Y S+
Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60
Query: 60 V---KDIVPQEAE-EFCRTGANFTLRELGLEEVTPPHGTLYRTDI-GLPHCGYSMGAGSD 114
K++ E EFC T + Y+TD+ + GY + GSD
Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLC--------------SGYQTDMHSVSRHGYQLEMGSD 106
Query: 115 ADMEADTVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQ--- 171
D E + SP+H +R+W R +S SSCLSSRANS L+LTDT+HE ++D G +
Sbjct: 107 VDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHER-KSDGENGFKFSP 165
Query: 172 --------------------NHARLRT--PPPPLSHAHTPNQHHAASINSLNRGNFTPRS 209
N R PPPP HA T + + +SL R + T RS
Sbjct: 166 VCCDMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRS 225
Query: 210 NPSPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMD 269
PSPA P Q+ H +W+LNSNIPLETR
Sbjct: 226 QPSPA-------APAPPTSTQDSVHLHNSWVLNSNIPLETR------------------- 259
Query: 270 ILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAF 328
HFLFK G G+S +F S YPLTS+TVYSPPPRPLPRSTF+RPAF
Sbjct: 260 --------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAF 305
Query: 329 NLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTAS 388
KP + CNWKC ALSA I+ TL +LLAY +A+HLFGL W LQP+EG++Y +
Sbjct: 306 TFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANGVSKGN 365
Query: 389 SWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPP 448
D + P GG + ++K F + ID+GE+D+G + Q IPP
Sbjct: 366 RGTESMDTTYSPIGGKVSDKSEKK-----------VFQKGRAIDTGEVDIGAQVMQTIPP 414
Query: 449 GTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEAR 508
G FWR Q+ I HP++LKFN+SL K +L+GIYGR+ +PP+HTQFDFV+L+DG++L+ Q+++
Sbjct: 415 GLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSK 474
Query: 509 SLEGTPRQSRGTVPPSSHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPS 568
+ T R + S ETGFI+Y+D G W+LAFYNDGK+ E V LTTAIE +D+C +
Sbjct: 475 GSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCST 534
Query: 569 NCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTN 628
NC GNG+CISG CHCF GFLGPDC R SCPVLC GNG+Y KG C+C GWKG ECDVP
Sbjct: 535 NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEE 594
Query: 629 QCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTN 688
QCID C HGTCI G CIC PGYKGE CEE DC+DP CS G+CV+GECHCS GWGG N
Sbjct: 595 QCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVN 654
Query: 689 CETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCED 748
CETP C +QCSGHGTFL D G+CSCDP WTG DCS E+C +CG HGVC G C+CE+
Sbjct: 655 CETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEE 714
Query: 749 GWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNG 808
GW+G C++R+CH C EHG C+DGKCECSPGW G+HCTIAHYLD V++GCPGLC GNG
Sbjct: 715 GWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLD-AVRDGCPGLCFGNG 773
Query: 809 RCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPL 868
RCTLD NGWHCVCQ+GW G GC+ ME CGD+ DNDGDGL DC+DPDCC Q C+I+PL
Sbjct: 774 RCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPL 833
Query: 869 CLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQV 928
C GSP+PLD+IQ++Q SQ FYDRIKFL+G+DSTH+IP E FD ACVIRGQV
Sbjct: 834 CQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQV 893
Query: 929 MTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWL 988
+ DGTPLVGVN+SF+++ +G+TISRQDGSFDLV GGIS+IL F+R+PF+ ++ TLWL
Sbjct: 894 VAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWL 953
Query: 989 PWDRFFVMETIIMRHEENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQAL 1048
PW++F V+E + M+ ++ PSCD+SNF PNP+V PSPLTSF SC E+G IVPE+Q +
Sbjct: 954 PWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVV 1013
Query: 1049 QEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAA 1108
QEEI I +RLSYLSSRTPGYK++LRI LTH TIP ++KVHL VAVEGRL +KWF A
Sbjct: 1014 QEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPA 1073
Query: 1109 APDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKL 1168
A +L Y F W+KTD+Y QKV+GL+EA VSVGYEYE+CPD ILWE+RT VLQG+E+DAS L
Sbjct: 1074 AINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNL 1133
Query: 1169 GGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNK 1228
GGWSL+KHH LN QSGI+HKGNGEN F+SQQPPVI +IMGNG +RS++C +CNG A NK
Sbjct: 1134 GGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNK 1193
Query: 1229 LLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPM 1288
L APVAL G DGS+YVGDFN++RRIFPSGN +ILELRN+D RHS SPAHKYYLA DP+
Sbjct: 1194 LFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPV 1253
Query: 1289 SGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLT 1348
S +++LSD+N+R+V+K+KS V KDL KN EVVAGTGDQCLPFD + CGDGG+A+EA+L
Sbjct: 1254 SESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLN 1313
Query: 1349 NPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEW 1408
+PRGITVD+ G IYFVDGTMIR+ID+N +I+T++GSN LTS +PLSCDS MDI+QV LEW
Sbjct: 1314 SPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEW 1373
Query: 1409 PTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLE 1468
PTDLA+NPMDNSLYVLDNN+VLQISEN +VRI+AGRP+HCQVPGIDHFL+SKVAIH+TLE
Sbjct: 1374 PTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLE 1433
Query: 1469 SATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDD 1528
SA A++VSH+G+L+IAETDE+K+NRI+QVTT+GEI ++AGAP+ CDCK D NCDCFSGD
Sbjct: 1434 SARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDG 1493
Query: 1529 GYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYL 1588
GYAKDAK+ PSSLAV DG LYVADLGN+RIR I +N+ LN N+YE++SP DQELY
Sbjct: 1494 GYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQ 1553
Query: 1589 FDTTGKHLYTQSLPTGDYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQ 1648
F G HL+T +L T DY+YNFTY +GD+ IT +NGN V++RRD+ GMPLWLVVP GQ
Sbjct: 1554 FTVNGTHLHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQ 1613
Query: 1649 VYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTF 1708
VYW+T+ +N LK V+ QG+ LA+MTY GN+GLLATKSNENGWTT YEYD G LTN TF
Sbjct: 1614 VYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATF 1673
Query: 1709 PTGQVSSFRSDTDSSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSL 1768
PTG+VSSF SD + V+++TS++++V ++TNL+A+ Y L Q+ +++Y + DGSL
Sbjct: 1674 PTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSL 1733
Query: 1769 RLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFG 1828
R+ A+GME+ L +EPH+LAG VNPT+GK N++LP ++ NL+EWRQRKEQ +G V+ F
Sbjct: 1734 RVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFE 1793
Query: 1829 RRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYS 1888
RRLR HNRNLLS+DFD +TRT KIYDDHRKFTLRILYDQ GRP LWSP SR N VN+TYS
Sbjct: 1794 RRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYS 1853
Query: 1889 PGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFD 1948
P G + IQRG +E+MEYDQ+G+I SR +ADGK WSYTYLEKS++LLLHSQR+YIFE+D
Sbjct: 1854 PSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYD 1913
Query: 1949 KNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGR 2008
+ D L SVTMP++ R +L+T+ SVGYYRNIY PP+ + S IQD++ DG LL T +LGTGR
Sbjct: 1914 QPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGR 1973
Query: 2009 RVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQI 2068
RV+YKY K ++L+E LYDTT+V+ TY+E++G++KTI+L ++GF CTIRYRQ GPLI RQI
Sbjct: 1974 RVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQI 2033
Query: 2069 FRFTEEGMVNARFDYNYDNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYY 2128
FRF+EEG+VNARFDY+Y N+FRVTSMQAVINETPLPIDLYRY DVSG+TEQFGKF VI Y
Sbjct: 2034 FRFSEEGLVNARFDYSY-NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINY 2092
Query: 2129 DINQIITTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYAN 2188
D+NQ+ITT VM HTK F A G++ EVQYEI +++ YWMT+QYDN+GR+V +++VG AN
Sbjct: 2093 DLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDAN 2152
Query: 2189 TTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRL 2248
TRY YEYDADGQLQTVS+NDK WRYSYDLNGN++LLS G SARLTPLRYD+RDRITRL
Sbjct: 2153 ITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRL 2212
Query: 2249 GDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSH 2308
G++QYKMDEDGFLRQRG DIFEYNS GLL KAYN+A W+V+Y YDGLGRRV+SKSS
Sbjct: 2213 GEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQ 2272
Query: 2309 HLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLA 2368
HLQFFYADLTNP +VTHLYNH+SSEITSLYYDLQGHL AMELSSG+E+Y+ACDN GTPLA
Sbjct: 2273 HLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLA 2332
Query: 2369 VFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRW 2428
VFS G +IK+ILYT YG+IY DT P+FQ+IIG+HGGLYD LTKLVH+G+RDYDV+AGRW
Sbjct: 2333 VFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRW 2392
Query: 2429 TSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPG 2488
T+P+H +WK L+ PFNLY F+NN P+ QD+ + TD+ SWL FGFQLHNV+PG
Sbjct: 2393 TTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPG 2451
Query: 2489 YPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTIT 2548
+PKP+++ +E +YEL+ Q KTQEWD K+ILG+QCE+QKQL+ F++L++
Sbjct: 2452 FPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDG 2511
Query: 2549 SCQQAPKTKKFASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLH 2608
C + K +FA+ SVFGKG+KFA+KDG VT DII VANED RR+AAILN+AHYLENLH
Sbjct: 2512 RCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLH 2571
Query: 2609 FTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQL 2668
FTI+G DTHYF+K G E DL ++G +GGRR LENGVNVTVSQ+ +VLNGRTRR+ DIQL
Sbjct: 2572 FTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQL 2631
Query: 2669 QYGALCLNTRYGTTLDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQV 2728
Q+GALC N RYGTT++EEK VLE+ARQRAV QAW +EQ+RL+EGEEG+RAWTEGEKQQ+
Sbjct: 2632 QHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQL 2691
Query: 2729 LSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769
LSTGRVQGYDG+FV+SVEQY ELSDSANNIHFMRQSE+GRR
Sbjct: 2692 LSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2732
>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
Length = 2731
Score = 3680 bits (9544), Expect = 0.0
Identities = 1753/2801 (62%), Positives = 2155/2801 (76%), Gaps = 102/2801 (3%)
Query: 1 MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSR 59
M+ + KPY+ L + + + + YTSSS +SE+G+ P++SY+S ETL Y+Q+ R+ Y S+
Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60
Query: 60 V---KDIVPQEAE-EFCRTGANFTLRELGLEEVTPPHGTLYRTDI-GLPHCGYSMGAGSD 114
K++ E EFC T + Y+TD+ + GY + GSD
Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLC--------------SGYQTDMHSVSRHGYQLEMGSD 106
Query: 115 ADMEADTVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQ--- 171
D E + SP+H +R+W R +S SSCLSSRANS L+LTDT+HE ++D G +
Sbjct: 107 VDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHER-KSDGENGFKFSP 165
Query: 172 --------------------NHARLRT--PPPPLSHAHTPNQHHAASINSLNRGNFTPRS 209
N R PPPP HA T + + +SL R + T RS
Sbjct: 166 VCCDMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRS 225
Query: 210 NPSPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMD 269
PSPA P Q+ H +W+LNSNIPLETR
Sbjct: 226 QPSPA-------APAPPTSTQDSVHLHNSWVLNSNIPLETR------------------- 259
Query: 270 ILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAF 328
HFLFK G G+S +F S YPLTS+TVYSPPPRPLPRSTF+RPAF
Sbjct: 260 --------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAF 305
Query: 329 NLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTAS 388
KP + CNWKC ALSA I+ TL +LLAY V +HLFGL W LQP+EG++Y +
Sbjct: 306 TFNKPYRCCNWKCTALSATAITVTLALLLAY-VIVHLFGLTWQLQPVEGELYANGVSKGN 364
Query: 389 SWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPP 448
D + P GG + ++K F + ID+GE+D+G + Q IPP
Sbjct: 365 RGTESMDTTYSPIGGKVSDKSEKK-----------VFQKGRAIDTGEVDIGAQVMQTIPP 413
Query: 449 GTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEAR 508
G FWR Q+ I HP++LKFN+SL K +L+GIYGR+ +PP+HTQFDFV+L+DG++L+ Q+++
Sbjct: 414 GLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSK 473
Query: 509 SLEGTPRQSRGTVPPSSHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPS 568
+ T R + S ETGFI+Y+D G W+LAFYNDGK+ E V LTTAIE +D+C +
Sbjct: 474 GSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCST 533
Query: 569 NCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTN 628
NC GNG+CISG CHCF GFLGPDC R SCPVLC GNG+Y KG C+C GWKG ECDVP
Sbjct: 534 NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEE 593
Query: 629 QCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTN 688
QCID C HGTCI G CIC PGYKGE CEE DC+DP CS G+CV+GECHCS GWGG N
Sbjct: 594 QCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVN 653
Query: 689 CETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCED 748
CETP C +QCSGHGTFL D G+CSCDP WTG DCS E+C +CG HGVC G C+CE+
Sbjct: 654 CETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEE 713
Query: 749 GWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNG 808
GW+G C++R+CH C EHG C+DGKCECSPGW G+HCTIAHYLD V++GCPGLC GNG
Sbjct: 714 GWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLD-AVRDGCPGLCFGNG 772
Query: 809 RCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPL 868
RCTLD NGWHCVCQ+GW G GC+ ME CGD+ DNDGDGL DC+DPDCC Q C+I+PL
Sbjct: 773 RCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPL 832
Query: 869 CLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQV 928
C GSP+PLD+IQ++Q SQ FYDRIKFL+G+DSTH+IP E FD ACVIRGQV
Sbjct: 833 CQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQV 892
Query: 929 MTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWL 988
+ DGTPLVGVN+SF+++ +G+TISRQDGSFDLV GGIS+IL F+R+PF+ ++ TLWL
Sbjct: 893 VAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWL 952
Query: 989 PWDRFFVMETIIMRHEENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQAL 1048
PW++F V+E + M+ ++ PSCD+SNF PNP+V PSPLTSF SC E+G IVPE+Q +
Sbjct: 953 PWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVV 1012
Query: 1049 QEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAA 1108
QEEI I +RLSYLSSRTPGYK++LRI LTH TIP ++KVHL VAVEGRL +KWF A
Sbjct: 1013 QEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPA 1072
Query: 1109 APDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKL 1168
A +L Y F W+KTD+Y QKV+GL+EA VSVGYEYE+CPD ILWE+RT VLQG+E+DAS L
Sbjct: 1073 AINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNL 1132
Query: 1169 GGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNK 1228
GGWSL+KHH LN QSGI+HKGNGEN F+SQQPPVI +IMGNG +RS++C +CNG A NK
Sbjct: 1133 GGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNK 1192
Query: 1229 LLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPM 1288
L APVAL G DGS+YVGDFN++RRIFPSGN +ILELRN+D RHS SPAHKYYLA DP+
Sbjct: 1193 LFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILELRNRDTRHSTSPAHKYYLAMDPV 1252
Query: 1289 SGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLT 1348
S +++LSD+N+R+V+K+KS V KDL KN EVVAGTGDQCLPFD + CGDGG+A+EA+L
Sbjct: 1253 SESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLN 1312
Query: 1349 NPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEW 1408
+PRGITVD+ G IYFVDGTMIR+ID+N +I+T++GSN LTS +PLSCDS MDI+QV LEW
Sbjct: 1313 SPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEW 1372
Query: 1409 PTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLE 1468
PTDLA+NPMDNSLYVLDNN+VLQISEN +VRI+AGRP+HCQVPGIDHFL+SKVAIH+TLE
Sbjct: 1373 PTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLE 1432
Query: 1469 SATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDD 1528
SA A++VSH+G+L+IAETDE+K+NRI+QVTT+GEI ++AGAP+ CDCK D NCDCFSGD
Sbjct: 1433 SARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDG 1492
Query: 1529 GYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYL 1588
GYAKDAK+ PSSLAV DG LYVADLGN+RIR I +N+ LN N+YE++SP DQELY
Sbjct: 1493 GYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQ 1552
Query: 1589 FDTTGKHLYTQSLPTGDYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQ 1648
F G HL+T +L T DY+YNFTY +GD+ IT +NGN V++RRD+ GMPLWLVVP GQ
Sbjct: 1553 FTVNGTHLHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQ 1612
Query: 1649 VYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTF 1708
VYW+T+ +N LK V+ QG+ LA+MTY GN+GLLATKSNENGWTT YEYD G LTN TF
Sbjct: 1613 VYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATF 1672
Query: 1709 PTGQVSSFRSDTDSSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSL 1768
PTG+VSSF SD + V+++TS++++V ++TNL+A+ Y L Q+ +++Y + DGSL
Sbjct: 1673 PTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSL 1732
Query: 1769 RLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFG 1828
R+ A+GME+ L +EPH+LAG VNPT+GK N++LP ++ NL+EWRQRKEQ +G V+ F
Sbjct: 1733 RVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFE 1792
Query: 1829 RRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYS 1888
RRLR HNRNLLS+DFD +TRT KIYDDHRKFTLRILYDQ GRP LWSP SR N VN+TYS
Sbjct: 1793 RRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYS 1852
Query: 1889 PGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFD 1948
P G + IQRG +E+MEYDQ+G+I SR +ADGK WSYTYLEKS++LLLHSQR+YIFE+D
Sbjct: 1853 PSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYD 1912
Query: 1949 KNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGR 2008
+ D L SVTMP++ R +L+T+ SVGYYRNIY PP+ + S IQD++ DG LL T +LGTGR
Sbjct: 1913 QPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGR 1972
Query: 2009 RVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQI 2068
RV+YKY K ++L+E LYDTT+V+ TY+E++G++KTI+L ++GF CTIRYRQ GPLI RQI
Sbjct: 1973 RVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQI 2032
Query: 2069 FRFTEEGMVNARFDYNYDNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYY 2128
FRF+EEG+VNARFDY+Y N+FRVTSMQAVINETPLPIDLYRY DVSG+TEQFGKF VI Y
Sbjct: 2033 FRFSEEGLVNARFDYSY-NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINY 2091
Query: 2129 DINQIITTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYAN 2188
D+NQ+ITT VM HTK F A G++ EVQYEI +++ YWMT+QYDN+GR+V +++VG AN
Sbjct: 2092 DLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDAN 2151
Query: 2189 TTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRL 2248
TRY YEYDADGQLQTVS+NDK WRYSYDLNGN++LLS G SARLTPLRYD+RDRITRL
Sbjct: 2152 ITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRL 2211
Query: 2249 GDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSH 2308
G++QYKMDEDGFLRQRG DIFEYNS GLL KAYN+A W+V+Y YDGLGRRV+SKSS
Sbjct: 2212 GEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQ 2271
Query: 2309 HLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLA 2368
HLQFFYADLTNP +VTHLYNH+SSEITSLYYDLQGHL AMELSSG+E+Y+ACDN GTPLA
Sbjct: 2272 HLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLA 2331
Query: 2369 VFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRW 2428
VFS G +IK+ILYT YG+IY DT P+FQ+IIG+HGGLYD LTKLVH+G+RDYDV+AGRW
Sbjct: 2332 VFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRW 2391
Query: 2429 TSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPG 2488
T+P+H +WK L+ PFNLY F+NN P+ QD+ + TD+ SWL FGFQLHNV+PG
Sbjct: 2392 TTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPG 2450
Query: 2489 YPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTIT 2548
+PKP+++ +E +YEL+ Q KTQEWD K+ILG+QCE+QKQL+ F++L++
Sbjct: 2451 FPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDG 2510
Query: 2549 SCQQAPKTKKFASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLH 2608
C + K +FA+ SVFGKG+KFA+KDG VT DII VANED RR+AAILN+AHYLENLH
Sbjct: 2511 RCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLH 2570
Query: 2609 FTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQL 2668
FTI+G DTHYF+K G E DL ++G +GGRR LENGVNVTVSQ+ +VLNGRTRR+ DIQL
Sbjct: 2571 FTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQL 2630
Query: 2669 QYGALCLNTRYGTTLDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQV 2728
Q+GALC N RYGTT++EEK VLE+ARQRAV QAW +EQ+RL+EGEEG+RAWTEGEKQQ+
Sbjct: 2631 QHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQL 2690
Query: 2729 LSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769
LSTGRVQGYDG+FV+SVEQY ELSDSANNIHFMRQSE+GRR
Sbjct: 2691 LSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2731
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 3668 bits (9511), Expect = 0.0
Identities = 1748/2801 (62%), Positives = 2150/2801 (76%), Gaps = 108/2801 (3%)
Query: 1 MDVKERKPYRSLTR-RRDAERRYTSSSADSEEGKAPQKSYSSSETLKAYDQDARLAYGSR 59
M+ + KPY+ L + + + + YTSSS +SE+G+ P++SY+S ETL Y+Q+ R+ Y S+
Sbjct: 1 MEQTDCKPYQPLPKVKHEMDLAYTSSSDESEDGRKPRQSYNSRETLHEYNQELRMNYNSQ 60
Query: 60 V---KDIVPQEAE-EFCRTGANFTLRELGLEEVTPPHGTLYRTDI-GLPHCGYSMGAGSD 114
K++ E EFC T + Y+TD+ + GY + GSD
Sbjct: 61 SRKRKEVEKSTQEMEFCETSHTLC--------------SGYQTDMHSVSRHGYQLEMGSD 106
Query: 115 ADMEADTVLSPEHPVRLWGRSTRSGRSSCLSSRANSNLTLTDTEHENTETDHPGGLQ--- 171
D E + SP+H +R+W R +S SSCLSSRANS L+LTDT+HE ++D G +
Sbjct: 107 VDTETEGAASPDHALRMWIRGMKSEHSSCLSSRANSALSLTDTDHER-KSDGENGFKFSP 165
Query: 172 --------------------NHARLRT--PPPPLSHAHTPNQHHAASINSLNRGNFTPRS 209
N R PPPP HA T + + +SL R + T RS
Sbjct: 166 VCCDMEAQAGSTQDVQSSPHNQFTFRPLPPPPPPPHACTCARKPPPAADSLQRRSMTTRS 225
Query: 210 NPSPAPTDHSLSGEPPAGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMD 269
PSPA P Q+ H +W+LNSNIPLETR
Sbjct: 226 QPSPA-------APAPPTSTQDSVHLHNSWVLNSNIPLETR------------------- 259
Query: 270 ILGASRHDGAYSDGHFLFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAF 328
HFLFK G G+S +F S YPLTS+TVYSPPPRPLPRSTF+RPAF
Sbjct: 260 --------------HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRSTFSRPAF 305
Query: 329 NLKKPSKYCNWKCAALSAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTAS 388
KP + CNWKC ALSA I+ TL +LLAY +A+HLFGL W LQP+EG++Y +
Sbjct: 306 TFNKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEGELYANGVSKGN 365
Query: 389 SWPVPTDVSLYPSGGTGLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPP 448
D + P GG + ++K F + ID+GE+D+G + Q IPP
Sbjct: 366 RGTESMDTTYSPIGGKVSDKSEKK-----------VFQKGRAIDTGEVDIGAQVMQTIPP 414
Query: 449 GTFWRSQVFIDHPVHLKFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEAR 508
G FWR Q+ I HP++LKFN+SL K +L+GIYGR+ +PP+HTQFDFV+L+DG++L+ Q+++
Sbjct: 415 GLFWRFQITIHHPIYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLVKQDSK 474
Query: 509 SLEGTPRQSRGTVPPSSHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPS 568
+ T R + S ETGFI+Y+D G W+LAFYNDGK+ E V LTTAIE +D+C +
Sbjct: 475 GSDDTQHSPRNLILTSLQETGFIEYMDQGPWYLAFYNDGKKMEQVFVLTTAIEIMDDCST 534
Query: 569 NCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTN 628
NC GNG+CISG CHCF GFLGPDC R SCPVLC GNG+Y KG C+C GWKG ECDVP
Sbjct: 535 NCNGNGECISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPEE 594
Query: 629 QCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTN 688
QCID C HGTCI G CIC PGYKGE CEE DC+DP CS G+CV+GECHCS GWGG N
Sbjct: 595 QCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGICVKGECHCSTGWGGVN 654
Query: 689 CETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCED 748
CETP C +QCSGHGTFL D G+CSCDP WTG DCS E+C +CG HGVC G C+CE+
Sbjct: 655 CETPLPVCQEQCSGHGTFLLDAGVCSCDPKWTGSDCSTELCTMECGSHGVCSRGICQCEE 714
Query: 749 GWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNG 808
GW+G C++R+CH C EHG C+DGKCECSPGW G+HCTIAHYLD V++GCPGLC GNG
Sbjct: 715 GWVGPTCEERSCHSHCTEHGQCKDGKCECSPGWEGDHCTIAHYLD-AVRDGCPGLCFGNG 773
Query: 809 RCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPL 868
RCTLD NGWHCVCQ+GW G GC+ ME CGD+ DNDGDGL DC+DPDCC Q C+I+PL
Sbjct: 774 RCTLDQNGWHCVCQVGWSGTGCNVVMEMLCGDNLDNDGDGLTDCVDPDCCQQSNCYISPL 833
Query: 869 CLGSPNPLDIIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQV 928
C GSP+PLD+IQ++Q SQ FYDRIKFL+G+DSTH+IP E FD ACVIRGQV
Sbjct: 834 CQGSPDPLDLIQQSQTLFSQHTSRLFYDRIKFLIGKDSTHVIPPEVSFDSRRACVIRGQV 893
Query: 929 MTSDGTPLVGVNISFVNNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWL 988
+ DGTPLVGVN+SF+++ +G+TISRQDGSFDLV GGIS+IL F+R+PF+ ++ TLWL
Sbjct: 894 VAIDGTPLVGVNVSFLHHSDYGFTISRQDGSFDLVAIGGISVILIFDRSPFLPEKRTLWL 953
Query: 989 PWDRFFVMETIIMRHEENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQAL 1048
PW++F V+E + M+ ++ PSCD+SNF PNP+V PSPLTSF SC E+G IVPE+Q +
Sbjct: 954 PWNQFIVVEKVTMQRVVSDPPSCDISNFISPNPIVLPSPLTSFGGSCPERGTIVPELQVV 1013
Query: 1049 QEEISISGCKMRLSYLSSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAA 1108
QEEI I +RLSYLSSRTPGYK++LRI LTH TIP ++KVHL VAVEGRL +KWF A
Sbjct: 1014 QEEIPIPSSFVRLSYLSSRTPGYKTLLRILLTHSTIPVGMIKVHLTVAVEGRLTQKWFPA 1073
Query: 1109 APDLSYYFIWDKTDVYNQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKL 1168
A +L Y F W+KTD+Y QKV+GL+EA VSVGYEYE+CPD ILWE+RT VLQG+E+DAS L
Sbjct: 1074 AINLVYTFAWNKTDIYGQKVWGLAEALVSVGYEYETCPDFILWEQRTVVLQGFEMDASNL 1133
Query: 1169 GGWSLDKHHALNIQSGILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNK 1228
GGWSL+KHH LN QSGI+HKGNGEN F+SQQPPVI +IMGNG +RS++C +CNG A NK
Sbjct: 1134 GGWSLNKHHILNPQSGIIHKGNGENMFISQQPPVISTIMGNGHQRSVACTNCNGPAHNNK 1193
Query: 1229 LLAPVALTCGSDGSLYVGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPM 1288
L APVAL G DGS+YVGDFN++RRIFPSGN +ILEL S SPAHKYYLA DP+
Sbjct: 1194 LFAPVALASGPDGSVYVGDFNFVRRIFPSGNSVSILEL-------STSPAHKYYLAMDPV 1246
Query: 1289 SGAVFLSDSNSRRVFKIKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLT 1348
S +++LSD+N+R+V+K+KS V KDL KN EVVAGTGDQCLPFD + CGDGG+A+EA+L
Sbjct: 1247 SESLYLSDTNTRKVYKLKSLVETKDLSKNFEVVAGTGDQCLPFDQSHCGDGGRASEASLN 1306
Query: 1349 NPRGITVDKFGLIYFVDGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEW 1408
+PRGITVD+ G IYFVDGTMIR+ID+N +I+T++GSN LTS +PLSCDS MDI+QV LEW
Sbjct: 1307 SPRGITVDRHGFIYFVDGTMIRKIDENAVITTVIGSNGLTSTQPLSCDSGMDITQVRLEW 1366
Query: 1409 PTDLAINPMDNSLYVLDNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLE 1468
PTDLA+NPMDNSLYVLDNN+VLQISEN +VRI+AGRP+HCQVPGIDHFL+SKVAIH+TLE
Sbjct: 1367 PTDLAVNPMDNSLYVLDNNIVLQISENRRVRIIAGRPIHCQVPGIDHFLVSKVAIHSTLE 1426
Query: 1469 SATALAVSHNGVLYIAETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDD 1528
SA A++VSH+G+L+IAETDE+K+NRI+QVTT+GEI ++AGAP+ CDCK D NCDCFSGD
Sbjct: 1427 SARAISVSHSGLLFIAETDERKVNRIQQVTTNGEIYIIAGAPTDCDCKIDPNCDCFSGDG 1486
Query: 1529 GYAKDAKLNTPSSLAVCADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYL 1588
GYAKDAK+ PSSLAV DG LYVADLGN+RIR I +N+ LN N+YE++SP DQELY
Sbjct: 1487 GYAKDAKMKAPSSLAVSPDGTLYVADLGNVRIRTISRNQAHLNDMNIYEIASPADQELYQ 1546
Query: 1589 FDTTGKHLYTQSLPTGDYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQ 1648
F G HL+T +L T DY+YNFTY +GD+ IT +NGN V++RRD+ GMPLWLVVP GQ
Sbjct: 1547 FTVNGTHLHTLNLITRDYVYNFTYNSEGDLGAITSSNGNSVHIRRDAGGMPLWLVVPGGQ 1606
Query: 1649 VYWVTMGTNSALKSVTTQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTF 1708
VYW+T+ +N LK V+ QG+ LA+MTY GN+GLLATKSNENGWTT YEYD G LTN TF
Sbjct: 1607 VYWLTISSNGVLKRVSAQGYNLALMTYPGNTGLLATKSNENGWTTVYEYDPEGHLTNATF 1666
Query: 1709 PTGQVSSFRSDTDSSVHVQVETSSKDDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSL 1768
PTG+VSSF SD + V+++TS++++V ++TNL+A+ Y L Q+ +++Y + DGSL
Sbjct: 1667 PTGEVSSFHSDLEKLTKVELDTSNRENVLMSTNLTATSTIYILKQENTQSTYRVNPDGSL 1726
Query: 1769 RLLLANGMEVALQTEPHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFG 1828
R+ A+GME+ L +EPH+LAG VNPT+GK N++LP ++ NL+EWRQRKEQ +G V+ F
Sbjct: 1727 RVTFASGMEIGLSSEPHILAGAVNPTLGKCNISLPGEHNANLIEWRQRKEQNKGNVSAFE 1786
Query: 1829 RRLRVHNRNLLSLDFDRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYS 1888
RRLR HNRNLLS+DFD +TRT KIYDDHRKFTLRILYDQ GRP LWSP SR N VN+TYS
Sbjct: 1787 RRLRAHNRNLLSIDFDHITRTGKIYDDHRKFTLRILYDQTGRPILWSPVSRYNEVNITYS 1846
Query: 1889 PGGYIAGIQRGIMSERMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFD 1948
P G + IQRG +E+MEYDQ+G+I SR +ADGK WSYTYLEKS++LLLHSQR+YIFE+D
Sbjct: 1847 PSGLVTFIQRGTWNEKMEYDQSGKIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYD 1906
Query: 1949 KNDRLSSVTMPNVARQTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGR 2008
+ D L SVTMP++ R +L+T+ SVGYYRNIY PP+ + S IQD++ DG LL T +LGTGR
Sbjct: 1907 QPDCLLSVTMPSMVRHSLQTMLSVGYYRNIYTPPDSSTSFIQDYSRDGRLLQTLHLGTGR 1966
Query: 2009 RVIYKYGKLSKLAETLYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQI 2068
RV+YKY K ++L+E LYDTT+V+ TY+E++G++KTI+L ++GF CTIRYRQ GPLI RQI
Sbjct: 1967 RVLYKYTKQARLSEVLYDTTQVTLTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQI 2026
Query: 2069 FRFTEEGMVNARFDYNYDNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYY 2128
FRF+EEG+VNARFDY+Y N+FRVTSMQAVINETPLPIDLYRY DVSG+TEQFGKF VI Y
Sbjct: 2027 FRFSEEGLVNARFDYSY-NNFRVTSMQAVINETPLPIDLYRYVDVSGRTEQFGKFSVINY 2085
Query: 2129 DINQIITTAVMTHTKHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYAN 2188
D+NQ+ITT VM HTK F A G++ EVQYEI +++ YWMT+QYDN+GR+V +++VG AN
Sbjct: 2086 DLNQVITTTVMKHTKIFSANGQVIEVQYEILKAIAYWMTIQYDNVGRMVICDIRVGVDAN 2145
Query: 2189 TTRYSYEYDADGQLQTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRL 2248
TRY YEYDADGQLQTVS+NDK WRYSYDLNGN++LLS G SARLTPLRYD+RDRITRL
Sbjct: 2146 ITRYFYEYDADGQLQTVSVNDKTQWRYSYDLNGNINLLSHGKSARLTPLRYDLRDRITRL 2205
Query: 2249 GDVQYKMDEDGFLRQRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSH 2308
G++QYKMDEDGFLRQRG DIFEYNS GLL KAYN+A W+V+Y YDGLGRRV+SKSS
Sbjct: 2206 GEIQYKMDEDGFLRQRGNDIFEYNSNGLLQKAYNKASGWTVQYYYDGLGRRVASKSSLGQ 2265
Query: 2309 HLQFFYADLTNPTKVTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLA 2368
HLQFFYADLTNP +VTHLYNH+SSEITSLYYDLQGHL AMELSSG+E+Y+ACDN GTPLA
Sbjct: 2266 HLQFFYADLTNPIRVTHLYNHTSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLA 2325
Query: 2369 VFSGTGLMIKQILYTAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRW 2428
VFS G +IK+ILYT YG+IY DT P+FQ+IIG+HGGLYD LTKLVH+G+RDYDV+AGRW
Sbjct: 2326 VFSSRGQVIKEILYTPYGDIYHDTYPDFQVIIGFHGGLYDFLTKLVHLGQRDYDVVAGRW 2385
Query: 2429 TSPDHELWKHLSSSNVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPG 2488
T+P+H +WK L+ PFNLY F+NN P+ QD+ + TD+ SWL FGFQLHNV+PG
Sbjct: 2386 TTPNHHIWKQLNLL-PKPFNLYSFENNYPVGKIQDVAKYTTDIRSWLELFGFQLHNVLPG 2444
Query: 2489 YPKPDMDAMEPSYELIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTIT 2548
+PKP+++ +E +YEL+ Q KTQEWD K+ILG+QCE+QKQL+ F++L++
Sbjct: 2445 FPKPELENLELTYELLRLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYNDG 2504
Query: 2549 SCQQAPKTKKFASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLH 2608
C + K +FA+ SVFGKG+KFA+KDG VT DII VANED RR+AAILN+AHYLENLH
Sbjct: 2505 RCLEGGKQPRFAAVPSVFGKGIKFAIKDGIVTADIIGVANEDSRRLAAILNNAHYLENLH 2564
Query: 2609 FTIDGVDTHYFVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQL 2668
FTI+G DTHYF+K G E DL ++G +GGRR LENGVNVTVSQ+ +VLNGRTRR+ DIQL
Sbjct: 2565 FTIEGRDTHYFIKLGSLEEDLVLIGNTGGRRILENGVNVTVSQMTSVLNGRTRRFADIQL 2624
Query: 2669 QYGALCLNTRYGTTLDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQV 2728
Q+GALC N RYGTT++EEK VLE+ARQRAV QAW +EQ+RL+EGEEG+RAWTEGEKQQ+
Sbjct: 2625 QHGALCFNIRYGTTVEEEKNHVLEIARQRAVAQAWTKEQRRLQEGEEGIRAWTEGEKQQL 2684
Query: 2729 LSTGRVQGYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769
LSTGRVQGYDG+FV+SVEQY ELSDSANNIHFMRQSE+GRR
Sbjct: 2685 LSTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR 2725
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 3650 bits (9464), Expect = 0.0
Identities = 1762/2854 (61%), Positives = 2183/2854 (76%), Gaps = 174/2854 (6%)
Query: 1 MDVKERKPYRSLTRRR-DAERRYTSSSADSEEGKAP-QKSYSSSETLKAYDQDARLAYGS 58
MDVK+R+ +RSLTR R E RYTSSS DSE+ + P QKSYSSSETLKAYD D+R+ YG+
Sbjct: 1 MDVKDRR-HRSLTRGRCGKECRYTSSSLDSEDCRVPTQKSYSSSETLKAYDHDSRMHYGN 59
Query: 59 RVKDIVPQEAEEFCRTGANFTLRELGLEEVTPPHGTLYRTDIGLPHCGYSMGAGSDADME 118
RV D++ +E++EF R G NFTL ELG+ E +P H + Y +D+G+ H GYS+ GSDAD +
Sbjct: 60 RVTDLIHRESDEFPRQGTNFTLAELGICEPSP-HRSGYCSDMGILHQGYSLSTGSDADSD 118
Query: 119 ADTVLSPEHPVRLW----------GRSTRSGRSSCLSSRANSN----------------- 151
+ +SPEH +RLW G S+R + L+ N N
Sbjct: 119 TEGGMSPEHAIRLWGRGIKSRRSSGLSSRENSALTLTDSDNENKSDDENGRPIPPTSSPS 178
Query: 152 ---------------------LTLTDTEHENTETD---------------------HPGG 169
L ++T H+ +T+ G
Sbjct: 179 LLPSAQLPSSHNPPPVSCQMPLLDSNTSHQIMDTNPDEEFSPNSYLLRACSGPQQASSSG 238
Query: 170 LQNHARLRT--PPPPLSHAHTPNQHHAASINSLNRGNFTPRSNP--SPAPTDHSLSGEPP 225
NH T PP P H HT + HH+ S NSLNR + T R + +PAP + L+ P
Sbjct: 239 PPNHHSQSTLRPPLPPPHNHTLSHHHS-SANSLNRNSLTNRRSQIHAPAPAPNDLATTP- 296
Query: 226 AGGAQEPAHAQENWLLNSNIPLETRNLGKQPFLGTLQDNLIEMDILGASRHDGAYSDGHF 285
E Q++W+LNSN+PLETR HF
Sbjct: 297 -----ESVQLQDSWVLNSNVPLETR---------------------------------HF 318
Query: 286 LFKPG-GTSPLFCTTSPGYPLTSSTVYSPPPRPLPRSTFARPAFNLKKPSKYCNWKCAAL 344
LFK G++PLF ++SPGYPLTS TVY+PPPR LPR+TF+R AF LKKPSKYC+WKCAAL
Sbjct: 319 LFKTSSGSTPLFSSSSPGYPLTSGTVYTPPPRLLPRNTFSRKAFKLKKPSKYCSWKCAAL 378
Query: 345 SAIVISATLVILLAYFVAMHLFGLNWHLQPMEGQMYEITEDTASSWPVPTDVSLYPSGGT 404
SAI + L ILLAYF+AMHL GLNW LQP +G + + P DV+ PSGG
Sbjct: 379 SAIAAALLLAILLAYFIAMHLLGLNWQLQPADGHTFN--NGIRTGLPGNDDVATMPSGGK 436
Query: 405 GLETPDRKGKGTTEGKPSSFFPEDSFIDSGEIDVGRRASQKIPPGTFWRSQVFIDHPVHL 464
P S ++S IDSGE +VGRR +Q++PPG FWRSQ+ I P L
Sbjct: 437 ---------------VPWSL--KNSSIDSGEAEVGRRVTQEVPPGVFWRSQIHISQPQFL 479
Query: 465 KFNVSLGKAALVGIYGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPS 524
KFN+SLGK AL G+Y R+GLPPSH Q+DF+E LDG+ E S+ +PR+ R
Sbjct: 480 KFNISLGKDALFGVYIRRGLPPSHAQYDFMERLDGK-----EKWSVVESPRERRSIQTLV 534
Query: 525 SHETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCF 584
+E F+QYLD G+WHLAFYNDGK+ E+VSF T ++SV +CP NC+GNG+C+SG CHCF
Sbjct: 535 QNEAVFVQYLDVGLWHLAFYNDGKDKEMVSFNTVVLDSVQDCPRNCHGNGECVSGVCHCF 594
Query: 585 LGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG 644
GFLG DC +A+CPVLCSGNGQY KG C C+SGWKGAECDVP NQCID +C HG+CI G
Sbjct: 595 PGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG 654
Query: 645 TCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHG 704
C+C+ GYKGE CEEVDC+DPTCS GVCV GEC CS GWGG NCE R C DQCSGHG
Sbjct: 655 NCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHG 714
Query: 705 TFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRC 764
T+LPDTGLCSCDP+W G DCS+E+C+ DCG HGVC+GG CRCE+GW GAACDQR CHPRC
Sbjct: 715 TYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRC 774
Query: 765 AEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLG 824
EHGTC+DGKCEC GWNGEHCTI +GCP LCNGNGRCTL N W CVCQ G
Sbjct: 775 IEHGTCKDGKCECREGWNGEHCTI---------DGCPDLCNGNGRCTLGQNSWQCVCQTG 825
Query: 825 WRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLDIIQETQV 884
WRG GC+ +MET+C D+KDN+GDGLVDC+DPDCCLQ C + LC GS +PLDIIQ+ Q
Sbjct: 826 WRGPGCNVAMETSCADNKDNEGDGLVDCLDPDCCLQSACQNSLLCRGSRDPLDIIQQGQT 885
Query: 885 PVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQVMTSDGTPLVGVNISFV 944
+ SFYDRIK L G+DSTHIIPGENPF+ +IRGQV+T+DGTPLVGVN+SFV
Sbjct: 886 --DWPAVKSFYDRIKLLAGKDSTHIIPGENPFNSSLVSLIRGQVVTTDGTPLVGVNVSFV 943
Query: 945 NNPLFGYTISRQDGSFDLVTNGGISIILRFERAPFITQEHTLWLPWDRFFVMETIIMRHE 1004
P +GYTI+RQDG+FDL+ NGG S+ L FERAPF++QE T+WLPW+ F+ M+T++M+ E
Sbjct: 944 KYPKYGYTITRQDGTFDLIANGGASLTLHFERAPFMSQERTVWLPWNSFYAMDTLVMKTE 1003
Query: 1005 ENEIPSCDLSNFARPNPVVSPSPLTSFASSCAEKGPIVPEIQALQEEISISGCKMRLSYL 1064
EN IPSCDLS F RP+P++ SPL++F S+ + PIVPE Q L EEI + G ++L YL
Sbjct: 1004 ENSIPSCDLSGFVRPDPIIISSPLSTFFSAAPGQNPIVPETQVLHEEIELPGSNVKLRYL 1063
Query: 1065 SSRTPGYKSVLRISLTHPTIPFNLMKVHLMVAVEGRLFRKWFAAAPDLSYYFIWDKTDVY 1124
SSRT GYKS+L+I++T T+P NL++VHLMVAVEG LF+K F A+P+L+Y FIWDKTD Y
Sbjct: 1064 SSRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEGHLFQKSFQASPNLAYTFIWDKTDAY 1123
Query: 1125 NQKVFGLSEAFVSVGYEYESCPDLILWEKRTTVLQGYEIDASKLGGWSLDKHHALNIQSG 1184
Q+V+GLS+A VSVG+EYE+CP LILWEKRT +LQG+E+D S LGGWSLDKHH LN++SG
Sbjct: 1124 GQRVYGLSDAVVSVGFEYETCPSLILWEKRTALLQGFELDPSNLGGWSLDKHHILNVKSG 1183
Query: 1185 ILHKGNGENQFVSQQPPVIGSIMGNGRRRSISCPSCNGLADGNKLLAPVALTCGSDGSLY 1244
ILHKG GENQF++QQP +I SIMGNGRRRSISCPSCNGLA+GNKLLAPVAL G DGSLY
Sbjct: 1184 ILHKGTGENQFLTQQPAIITSIMGNGRRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLY 1243
Query: 1245 VGDFNYIRRIFPSGNVTNILELRNKDFRHSHSPAHKYYLATDPMSGAVFLSDSNSRRVFK 1304
VGDFNYIRRIFPS NVT+ILELRNK+F+HS++PAHKYYLA DP+SG++++SD+NSRR+++
Sbjct: 1244 VGDFNYIRRIFPSRNVTSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYR 1303
Query: 1305 IKSTVVVKDLVKNSEVVAGTGDQCLPFDDTRCGDGGKATEATLTNPRGITVDKFGLIYFV 1364
+KS KDL NSEVVAGTG+QCLPFD+ RCGDGGKA +ATL +PRGI VDK GL+YFV
Sbjct: 1304 VKSLSGTKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAIDATLMSPRGIAVDKNGLMYFV 1363
Query: 1365 DGTMIRRIDQNGIISTLLGSNDLTSARPLSCDSVMDISQVHLEWPTDLAINPMDNSLYVL 1424
D TMIR++DQNGIISTLLGSNDLT+ RPLSCDS MD++QV LEWPTDLA+NPMDNSLYVL
Sbjct: 1364 DATMIRKVDQNGIISTLLGSNDLTAVRPLSCDSSMDVAQVRLEWPTDLAVNPMDNSLYVL 1423
Query: 1425 DNNVVLQISENHQVRIVAGRPMHCQVPGIDHFLLSKVAIHATLESATALAVSHNGVLYIA 1484
+NNV+L+I+ENHQV I+AGRPMHCQVPGID + LSK+AIH+ LESA+A+A+SH GVLYI
Sbjct: 1424 ENNVILRITENHQVSIIAGRPMHCQVPGID-YSLSKLAIHSALESASAIAISHTGVLYIT 1482
Query: 1485 ETDEKKINRIRQVTTSGEISLVAGAPSGCDCKNDANCDCFSGDDGYAKDAKLNTPSSLAV 1544
ETDEKKINR+RQVTT+GEI L+AGA S CDCKND NC+C+SGDD YA DA LN+PSSLAV
Sbjct: 1483 ETDEKKINRLRQVTTNGEICLLAGAASDCDCKNDVNCNCYSGDDAYATDAILNSPSSLAV 1542
Query: 1545 CADGELYVADLGNIRIRFIRKNKPFLNTQNMYELSSPIDQELYLFDTTGKHLYTQSLPTG 1604
DG +Y+ADLGNIRIR + KNKP LN N YE +SP +QELY+F+ G H YT SL TG
Sbjct: 1543 APDGTIYIADLGNIRIRAVSKNKPVLNAFNQYEAASPGEQELYVFNADGIHQYTVSLVTG 1602
Query: 1605 DYLYNFTYTGDGDITLITDNNGNMVNVRRDSTGMPLWLVVPDGQVYWVTMGTNSALKSVT 1664
+YLYNFTY+ D D+T + DNNGN + +RRDS+GMP L++PD Q+ +T+GTN LK V+
Sbjct: 1603 EYLYNFTYSTDNDVTELIDNNGNSLKIRRDSSGMPRHLLMPDNQIITLTVGTNGGLKVVS 1662
Query: 1665 TQGHELAMMTYHGNSGLLATKSNENGWTTFYEYDSFGRLTNVTFPTGQVSSFRSDTDSSV 1724
TQ EL +MTY GN+GLLATKS+E GWTTFY+YD GRLTNVT PTG V+S + + S+
Sbjct: 1663 TQNLELGLMTYDGNTGLLATKSDETGWTTFYDYDHEGRLTNVTRPTGVVTSLHREMEKSI 1722
Query: 1725 HVQVETSSK-DDVTITTNLSASGAFYTLLQDQVRNSYYIGADGSLRLLLANGMEVALQTE 1783
+ +E S++ DDVT+ TNLS+ A YT++QDQVRNSY + +G+LR++ ANGM ++ +E
Sbjct: 1723 TIDIENSNRDDDVTVITNLSSVEASYTVVQDQVRNSYQLCNNGTLRVMYANGMGISFHSE 1782
Query: 1784 PHLLAGTVNPTVGKRNVTLPIDNGLNLVEWRQRKEQARGQVTVFGRRLRVHNRNLLSLDF 1843
PH+LAGT+ PT+G+ N++LP++NGLN +EWR RKEQ +G+VT+FGR+LRVH RNLLS+D+
Sbjct: 1783 PHVLAGTITPTIGRCNISLPMENGLNSIEWRLRKEQIKGKVTIFGRKLRVHGRNLLSIDY 1842
Query: 1844 DRVTRTEKIYDDHRKFTLRILYDQAGRPSLWSPSSRLNGVNVTYSPGGYIAGIQRGIMSE 1903
DR RTEKIYDDHRKFTLRI+YDQ GRP LW PSS L VNV+Y G +AG+QRG MSE
Sbjct: 1843 DRNIRTEKIYDDHRKFTLRIIYDQVGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSE 1902
Query: 1904 RMEYDQAGRITSRIFADGKTWSYTYLEKSMVLLLHSQRQYIFEFDKNDRLSSVTMPNVAR 1963
R + D+ GRI SR+FADGK WSY+YL+KSMVLLL SQRQYIFE+D +DRL +VTMP+VAR
Sbjct: 1903 RTDIDKQGRIVSRMFADGKVWSYSYLDKSMVLLLQSQRQYIFEYDSSDRLLAVTMPSVAR 1962
Query: 1964 QTLETIRSVGYYRNIYQPPEGNASVIQDFTEDGHLLHTFYLGTGRRVIYKYGKLSKLAET 2023
++ T S+GY RNIY PPE NASVI D+++DG +L T +LGTGR+V YKYGKLSKL+E
Sbjct: 1963 HSMSTHTSIGYIRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQVFYKYGKLSKLSEI 2022
Query: 2024 LYDTTKVSFTYDETAGMLKTINLQNEGFTCTIRYRQIGPLIDRQIFRFTEEGMVNARFDY 2083
+YD+T V+F YDET G+LK +NLQ+ GF+CTIRYR+IGPL+D+QI+RF+EEGMVNARFDY
Sbjct: 2023 VYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKIGPLVDKQIYRFSEEGMVNARFDY 2082
Query: 2084 NY-DNSFRVTSMQAVINETPLPIDLYRYDDVSGKTEQFGKFGVIYYDINQIITTAVMTHT 2142
Y DNSFR+ S++ VI+ETPLP+DLYRYD++SGK E FGKFGVIYYDINQIITTAVMT +
Sbjct: 2083 TYHDNSFRIASIKPVISETPLPVDLYRYDEISGKVEHFGKFGVIYYDINQIITTAVMTLS 2142
Query: 2143 KHFDAYGRMKEVQYEIFRSLMYWMTVQYDNMGRVVKKELKVGPYANTTRYSYEYDADGQL 2202
KHFD +GR+KEVQYE+FRSLMYWMTVQYD+MGRV+K+ELK+GPYANTT+Y+Y+YD DGQL
Sbjct: 2143 KHFDTHGRIKEVQYEMFRSLMYWMTVQYDSMGRVIKRELKLGPYANTTKYTYDYDGDGQL 2202
Query: 2203 QTVSINDKPLWRYSYDLNGNLHLLSPGNSARLTPLRYDIRDRITRLGDVQYKMDEDGFLR 2262
Q+V++ND+P WRYSYDLNGNLHLL+PGNS RL PLRYD+RDRITRLGDVQYK+D+DG+L
Sbjct: 2203 QSVAVNDRPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDVQYKIDDDGYLC 2262
Query: 2263 QRGGDIFEYNSAGLLIKAYNRAGSWSVRYRYDGLGRRVSSKSSHSHHLQFFYADLTNPTK 2322
QRG DIFEYNS GLL +AYN+A WSV+YRYDG+GRR S K++ HHLQ+FY+DL NPT+
Sbjct: 2263 QRGSDIFEYNSKGLLTRAYNKASGWSVQYRYDGVGRRASYKTNLGHHLQYFYSDLHNPTR 2322
Query: 2323 VTHLYNHSSSEITSLYYDLQGHLFAMELSSGDEFYIACDNIGTPLAVFSGTGLMIKQILY 2382
+TH+YNHS+SEITSLYYDLQGHLFAME SSG+E+Y+A DN GTPLAVFS GLMIKQ+ Y
Sbjct: 2323 ITHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVASDNTGTPLAVFSINGLMIKQLQY 2382
Query: 2383 TAYGEIYMDTNPNFQIIIGYHGGLYDPLTKLVHMGRRDYDVLAGRWTSPDHELWKHLSSS 2442
TAYGEIY D+NP+FQ++IG+HGGLYDPLTKLVH +RDYDVLAGRWTSPD+ +WK++
Sbjct: 2383 TAYGEIYYDSNPDFQMVIGFHGGLYDPLTKLVHFTQRDYDVLAGRWTSPDYTMWKNVGKE 2442
Query: 2443 NVMPFNLYMFKNNNPISNSQDIKCFMTDVNSWLLTFGFQLHNVIPGYPKPDMDAMEPSYE 2502
PFNLYMFK+NNP+S+ D+K ++TDV SWL+ FGFQL N+IPG+P+ M + P YE
Sbjct: 2443 PA-PFNLYMFKSNNPLSSELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVPPPYE 2501
Query: 2503 LIHTQMKTQEWDNSKSILGVQCEVQKQLKAFVTLERFDQLYGSTITSCQQAPKTKK---- 2558
L +Q +N + I GVQ ++ +AF+ LE G IT A +K
Sbjct: 2502 LSESQAS----ENGQLITGVQQTTERHNQAFMALE------GQVITKKLHASIREKAGHW 2551
Query: 2559 FASSGSVFGKGVKFALKDGRVTTDIISVANEDGRRVAAILNHAHYLENLHFTIDGVDTHY 2618
FA++ + GKG+ FA+K+GRVTT + S+A+ED R+VA++LN+A+YL+ +H++I+G DTHY
Sbjct: 2552 FATTTPIIGKGIMFAIKEGRVTTGVSSIASEDSRKVASVLNNAYYLDKMHYSIEGKDTHY 2611
Query: 2619 FVKPGPSEGDLAILGLSGGRRTLENGVNVTVSQINTVLNGRTRRYTDIQLQYGALCLNTR 2678
FVK G ++GDL LG + GR+ LE+GVNVTVSQ ++NGRTRR+T+I+ QY L L+ R
Sbjct: 2612 FVKIGSADGDLVTLGTTIGRKVLESGVNVTVSQPTLLVNGRTRRFTNIEFQYSTLLLSIR 2671
Query: 2679 YG---TTLDEEKARVLELARQRAVRQAWAREQQRLREGEEGLRAWTEGEKQQVLSTGRVQ 2735
YG TLDEEKARVL+ ARQRA+ AWA+EQQ+ R+G EG R WTEGEKQQ+LSTGRVQ
Sbjct: 2672 YGLTPDTLDEEKARVLDQARQRALGTAWAKEQQKARDGREGSRLWTEGEKQQLLSTGRVQ 2731
Query: 2736 GYDGFFVISVEQYPELSDSANNIHFMRQSEMGRR 2769
GY+G++V+ VEQYPEL+DS++NI F+RQ+EMG+R
Sbjct: 2732 GYEGYYVLPVEQYPELADSSSNIQFLRQNEMGKR 2765
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 223 bits (568), Expect = 2e-57
Identities = 114/302 (37%), Positives = 153/302 (50%), Gaps = 31/302 (10%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSG-NGQYMKGRCLCHSGWKGAECD 624
CPS+C G C++G C CF G+ G DC R CPV CS +G + G C+CH G+ G +C+
Sbjct: 221 CPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCN 280
Query: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
P C++ C N G C+ C+C+ G+ GE C E+ C + C RG C+ G C+C G+
Sbjct: 281 KPL--CLN-NCYNRGRCVENECVCDEGFTGEDCSELICPND-CFDRGRCINGTCYCEEGF 336
Query: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
G +C P TC C G + G C CD + G DCS + C ADC G CV G C
Sbjct: 337 TGEDCGKP--TCPHACHTQGRC--EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRC 392
Query: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
C+DG+ GA C + C C+ HG C +G+C C G+ GE C+ + CP C
Sbjct: 393 ECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS---------QLRCPNDC 443
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC-DTSMETAC--------GDSKDNDGDGLVDCMDP 855
+ GRC CVC+ G++G C D S C G +DG DC D
Sbjct: 444 HSRGRCV----EGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDR 499
Query: 856 DC 857
C
Sbjct: 500 QC 501
Score = 222 bits (565), Expect = 5e-57
Identities = 112/299 (37%), Positives = 151/299 (50%), Gaps = 32/299 (10%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
CP++C+ G CI+GTC+C GF G DCG+ +CP C G+ +G+C+C G+ G +C
Sbjct: 315 CPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS- 373
Query: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWG 685
+C C N G C+ G C C+ G+ G C E+ C + CSG G CV G+C C G+
Sbjct: 374 -EKRC-PADCHNRGRCVDGRCECDDGFTGADCGELKCPNG-CSGHGRCVNGQCVCDEGYT 430
Query: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR 745
G +C R C + C G + G C C+ + G+DCS C DC HG CV G C
Sbjct: 431 GEDCSQLR--CPNDCHSRGRCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCV 486
Query: 746 CEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCN 805
C+DG+ G C R C C+ G C DG+C C G+ G C + CP C+
Sbjct: 487 CDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDC---------AELSCPNDCH 537
Query: 806 GNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCH 864
G GRC +NG CVC G+ G C E C +D G C+D C +CH
Sbjct: 538 GQGRC---VNG-QCVCHEGFMGKDC---KEQRC----PSDCHGQGRCVDGQC----ICH 581
Score = 196 bits (499), Expect = 2e-49
Identities = 90/238 (37%), Positives = 129/238 (54%), Gaps = 17/238 (7%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
CP+ C G+G C++G C C G+ G DC + CP C G+ ++G+C+C G+KG +C
Sbjct: 408 CPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS- 466
Query: 626 PTNQCIDVACSN----HGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCS 681
D++C N HG C+ G C+C+ GY GE C + C CS RG+CV G+C C
Sbjct: 467 ------DMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQC-PRDCSNRGLCVDGQCVCE 519
Query: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVG 741
G+ G +C +C + C G G + G C C + G DC + C +DC G G CV
Sbjct: 520 DGFTGPDCA--ELSCPNDCHGQGRCV--NGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVD 575
Query: 742 GTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCT-IAHYLDRVVKE 798
G C C +G+ G C Q +C C G C G+C C+ G++GE C+ ++ D VV E
Sbjct: 576 GQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTE 633
Score = 182 bits (463), Expect = 3e-45
Identities = 108/337 (32%), Positives = 145/337 (43%), Gaps = 47/337 (13%)
Query: 570 CYGNGDCISGTCHCFL--GFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPT 627
C G G+ + C C G+ GP+C CP C G+ + G+C+C G+ G +C +
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDC---S 217
Query: 628 NQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGT 687
C++ G C+ G CIC GY G C C P G CV G C C G+ G
Sbjct: 218 QLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGD 277
Query: 688 NCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCE 747
+C P CL+ C G + + C CD +TG DCS IC DC G C+ GTC CE
Sbjct: 278 DCNKP--LCLNNCYNRGRCVENE--CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCE 333
Query: 748 DGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCT------IAHYLDRVV----- 796
+G+ G C + C C G C +G+C C G+ G C+ H R V
Sbjct: 334 EGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCE 393
Query: 797 -----------KEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC-------DTSMETAC 838
+ CP C+G+GRC +NG CVC G+ G C D C
Sbjct: 394 CDDGFTGADCGELKCPNGCSGHGRC---VNG-QCVCDEGYTGEDCSQLRCPNDCHSRGRC 449
Query: 839 GDSKDNDGDGL--VDCMDPDC---CLQPLCHINPLCL 870
+ K G DC D C C Q +N +C+
Sbjct: 450 VEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCV 486
Score = 107 bits (268), Expect = 1e-22
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 3/96 (3%)
Query: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
+CP++C+G G C++G C C GF+G DC CP C G G+ + G+C+CH G+ G +C
Sbjct: 531 SCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCG 590
Query: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV 660
C+N G C++G CICN GY GE C EV
Sbjct: 591 ---QHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEV 623
Score = 96.7 bits (239), Expect = 3e-19
Identities = 64/207 (30%), Positives = 86/207 (41%), Gaps = 37/207 (17%)
Query: 680 CSVGWGGTNCETPRATCLDQ---CSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGH 736
C+ G G C P LD CSG G F + C C+P W G +CS C +C
Sbjct: 140 CTAGAGC--CLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLR 197
Query: 737 GVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVV 796
G C+ G C C+DG+ G C Q AC C + G C +G C C G+ G C+
Sbjct: 198 GRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCS--------- 248
Query: 797 KEGCPGLCN-GNGRCTLDLNGWHCVCQLGWRGAGCDTSM--------------ETACGDS 841
+E CP C+ +G C L CVC G+ G C+ + E C +
Sbjct: 249 REICPVPCSEEHGTCVDGL----CVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEG 304
Query: 842 -KDNDGDGLV---DCMDPDCCLQPLCH 864
D L+ DC D C+ C+
Sbjct: 305 FTGEDCSELICPNDCFDRGRCINGTCY 331
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 220 bits (561), Expect = 1e-56
Identities = 114/305 (37%), Positives = 148/305 (48%), Gaps = 36/305 (11%)
Query: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
V +CP +C G C G C C+ G+ G DCG +CP C G G+ G C+C++G+ G +
Sbjct: 401 VRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
Query: 623 CDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSV 682
C V + C G C +G C+C PGY G C C C GRG CV G C C+
Sbjct: 461 CGV---RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD-CRGRGRCVDGRCVCNP 516
Query: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGG 742
G+ G +C + R C C GHG L + G+C CD ++G DCS C C G G C+ G
Sbjct: 517 GFTGEDCGSRR--CPGDCRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG 572
Query: 743 TCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
C CEDG+ G C R C C++HG C+DG C C G+ E C+I CP
Sbjct: 573 RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSI---------RTCPS 623
Query: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP- 861
C+G GRC C+C G+ G C T M A DC C+Q
Sbjct: 624 NCHGRGRC----EEGRCLCDPGYTGPTCATRMCPA-------------DCRGRGRCVQGV 666
Query: 862 -LCHI 865
LCH+
Sbjct: 667 CLCHV 671
Score = 215 bits (547), Expect = 6e-55
Identities = 107/266 (40%), Positives = 130/266 (48%), Gaps = 21/266 (7%)
Query: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
+CP +C G G C+ G C C GF GPDC + SCP CS G+ GRC+C G+ G +C
Sbjct: 217 SCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCG 276
Query: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
+ + CS G C G C+CNPGY GE C C CS RG C G C C G+
Sbjct: 277 M---RSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCKDGRCVCDPGY 332
Query: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
G +C T +C C G + G C C P +TG DCS C DC G G C G C
Sbjct: 333 TGEDCGT--RSCPWDCGEGGRCVD--GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGEC 388
Query: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
C+ G+ G C R+C C + G C DG+C C PG+ G C CP C
Sbjct: 389 ICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCG---------SRACPRDC 439
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC 830
G GRC NG CVC G+ G C
Sbjct: 440 RGRGRCE---NG-VCVCNAGYSGEDC 461
Score = 213 bits (541), Expect = 3e-54
Identities = 102/266 (38%), Positives = 130/266 (48%), Gaps = 21/266 (7%)
Query: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECD 624
+CP +C G C+ G C CF G+ GP CG SCP C G G+ ++G C+C +G+ G +C
Sbjct: 186 SCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDC- 244
Query: 625 VPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGW 684
+ + CS G C G C+C+PGY G+ C C CS RG C G C C+ G+
Sbjct: 245 --SQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSC-PRGCSQRGRCENGRCVCNPGY 301
Query: 685 GGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTC 744
G +C +C CS G G C CDP +TG DC C DCG G CV G C
Sbjct: 302 TGEDCGV--RSCPRGCSQRGRC--KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRC 357
Query: 745 RCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
C G+ G C R C C G C DG+C C G++G+ C + CPG C
Sbjct: 358 VCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGV---------RSCPGDC 408
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC 830
N GRC CVC G+ G C
Sbjct: 409 NQRGRC----EDGRCVCWPGYTGTDC 430
Score = 208 bits (530), Expect = 5e-53
Identities = 107/295 (36%), Positives = 141/295 (47%), Gaps = 23/295 (7%)
Query: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
V +CP +C G G C SG C C+ G+ G DCG +CP C G G+ + GRC+C+ G+ G +
Sbjct: 463 VRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGED 522
Query: 623 CDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSV 682
C + +C C HG C G C+C+ GY GE C C C GRG C+ G C C
Sbjct: 523 CG--SRRCPG-DCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGG-CRGRGQCLDGRCVCED 578
Query: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGG 742
G+ G +C + C + CS HG G+C C + DCSI C ++C G G C G
Sbjct: 579 GYSGEDCGVRQ--CPNDCSQHGVC--QDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
Query: 743 TCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
C C+ G+ G C R C C G C G C C G+ GE C + CPG
Sbjct: 635 RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCG----QEEPPASACPG 690
Query: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDC 857
C C CVC G+RG C +++T GD + G +C D C
Sbjct: 691 GCGPRELC----RAGQCVCVEGFRGPDC--AIQTCPGDCR-----GRGECHDGSC 734
Score = 205 bits (521), Expect = 6e-52
Identities = 116/332 (34%), Positives = 142/332 (42%), Gaps = 55/332 (16%)
Query: 563 VDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAE 622
V +CP C G C G C C G+ G DCG SCP C G+ + GRC+C G+ G +
Sbjct: 308 VRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGED 367
Query: 623 CDVPT-------------NQCI-DVA--------------CSNHGTCITGTCICNPGYKG 654
C T +CI D C+ G C G C+C PGY G
Sbjct: 368 CSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTG 427
Query: 655 ESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCS 714
C C C GRG C G C C+ G+ G +C +C C G G ++G C
Sbjct: 428 TDCGSRAC-PRDCRGRGRCENGVCVCNAGYSGEDCGV--RSCPGDCRGRGRC--ESGRCM 482
Query: 715 CDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGK 774
C P +TG DC C DC G G CV G C C G+ G C R C C HG C DG
Sbjct: 483 CWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGV 542
Query: 775 CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC---- 830
C C G++GE C+ CPG C G G+C L+G CVC+ G+ G C
Sbjct: 543 CVCDAGYSGEDCS---------TRSCPGGCRGRGQC---LDG-RCVCEDGYSGEDCGVRQ 589
Query: 831 ---DTSMETACGDSKDNDGDGLV--DCMDPDC 857
D S C D +G V DC C
Sbjct: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTC 621
Score = 179 bits (453), Expect = 4e-44
Identities = 89/226 (39%), Positives = 106/226 (46%), Gaps = 13/226 (5%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
CP +C G+G C G C C G+ G DC SCP C G GQ + GRC+C G+ G +C V
Sbjct: 528 CPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGV 587
Query: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWG 685
QC + CS HG C G CIC GY E C C C GRG C G C C G+
Sbjct: 588 --RQCPN-DCSQHGVCQDGVCICWEGYVSEDCSIRTCPS-NCHGRGRCEEGRCLCDPGYT 643
Query: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIE-----ICAADCGGHGVCV 740
G C T C C G G + G+C C + G DC E C CG +C
Sbjct: 644 GPTCAT--RMCPADCRGRGRCVQ--GVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR 699
Query: 741 GGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHC 786
G C C +G+ G C + C C G C DG C C G+ GE C
Sbjct: 700 AGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDC 745
Score = 176 bits (446), Expect = 3e-43
Identities = 92/275 (33%), Positives = 120/275 (43%), Gaps = 36/275 (13%)
Query: 571 YGNGDCISGTCHCFLGFLGPDCG---------------RASCPVLCSGNGQYMKGRCLCH 615
+G D TC C G+ GP C SCP C+ G+ ++GRC+C
Sbjct: 146 HGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCF 205
Query: 616 SGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVR 675
G+ G C P+ C G C+ G C+C G+ G C + C CS RG C
Sbjct: 206 PGYTGPSCGWPS---CPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSC-PRGCSQRGRCEG 261
Query: 676 GECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGG 735
G C C G+ G +C +C CS G + G C C+P +TG DC + C C
Sbjct: 262 GRCVCDPGYTGDDC--GMRSCPRGCSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQ 317
Query: 736 HGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRV 795
G C G C C+ G+ G C R+C C E G C DG+C C PG+ GE C+
Sbjct: 318 RGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCS-------- 369
Query: 796 VKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
CP C G GRC C+C G+ G C
Sbjct: 370 -TRTCPRDCRGRGRC----EDGECICDTGYSGDDC 399
Score = 173 bits (439), Expect = 2e-42
Identities = 94/275 (34%), Positives = 122/275 (44%), Gaps = 34/275 (12%)
Query: 593 GRASCPVLCSGNGQYMKGRCLC--HSGWKGAECDVPTNQCIDVA------------CSNH 638
G+ LCS +G + RC C GW G C PT+ I + C++
Sbjct: 135 GQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQ 194
Query: 639 GTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLD 698
G C+ G C+C PGY G SC C C GRG CV+G C C G+ G +C + +C
Sbjct: 195 GRCVRGRCVCFPGYTGPSCGWPSCPGD-CQGRGRCVQGVCVCRAGFSGPDCS--QRSCPR 251
Query: 699 QCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQR 758
CS G + G C CDP +TG DC + C C G C G C C G+ G C R
Sbjct: 252 GCSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVR 309
Query: 759 ACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWH 818
+C C++ G C+DG+C C PG+ GE C CP C GRC
Sbjct: 310 SCPRGCSQRGRCKDGRCVCDPGYTGEDCG---------TRSCPWDCGEGGRCV----DGR 356
Query: 819 CVCQLGWRGAGCDTSM--ETACGDSKDNDGDGLVD 851
CVC G+ G C T G + DG+ + D
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICD 391
Score = 112 bits (281), Expect = 4e-24
Identities = 50/130 (38%), Positives = 64/130 (49%), Gaps = 3/130 (2%)
Query: 562 SVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGA 621
S+ CPSNC+G G C G C C G+ GP C CP C G G+ ++G CLCH G+ G
Sbjct: 617 SIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGE 676
Query: 622 EC--DVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECH 679
+C + P C C G C+C G++G C C C GRG C G C
Sbjct: 677 DCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTC-PGDCRGRGECHDGSCV 735
Query: 680 CSVGWGGTNC 689
C G+ G +C
Sbjct: 736 CKDGYAGEDC 745
Score = 42.0 bits (97), Expect = 0.008
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 562 SVDNCPSNCYGNGDCISGTCHCFLGFLGPDCG 593
++ CP +C G G+C G+C C G+ G DCG
Sbjct: 715 AIQTCPGDCRGRGECHDGSCVCKDGYAGEDCG 746
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 147 bits (372), Expect = 1e-34
Identities = 108/355 (30%), Positives = 150/355 (42%), Gaps = 53/355 (14%)
Query: 563 VDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRASCPVLCS----GN--GQYMKGR 611
+D C SN C CI+G C C G P C L + GN G +
Sbjct: 683 IDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYK 742
Query: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGESCE-EVD-CMDP 665
CLC +GW G C+V N+C+ C N GTC + G C C G+KG +C+ +D C
Sbjct: 743 CLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASN 802
Query: 666 TCSGRGVC---VRG-ECHCSVGWGGTNCETPRATCLDQ-------CSGHGTFLPDTGLCS 714
C +G C + G CHC + + G NC+T A C C F ++ C
Sbjct: 803 PCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNF--ESYTCL 860
Query: 715 CDPSWTGHDCSIEI---CAADCGGHGVCVGG----TCRCEDGWMGAAC----DQRACHPR 763
C P W G C+I+I + C HG+C C C G+ G C D +P
Sbjct: 861 CAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANP- 919
Query: 764 CAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 819
C G+C DG C C PG+ G+ C + E C G C+ +N + C
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKC------QTDMNECLSEPCKNGGTCSDYVNSYTC 973
Query: 820 VCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPN 874
CQ G+ G C+ ++ C +S +G VD ++ CL P+ CL N
Sbjct: 974 KCQAGFDGVHCENNI-NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEIN 1027
Score = 139 bits (351), Expect = 3e-32
Identities = 115/416 (27%), Positives = 162/416 (38%), Gaps = 64/416 (15%)
Query: 570 CYGNGDCIS-----GTCHCFLGFLGPDC--------GRASCPVLCSGNGQYMKGRCLCHS 616
C G C++ G C C GFLG C R C K C C S
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 617 GWKGAECDVPTNQCIDVA--CSNHGTCI-----TGTCICNPGYKGESCEEVD-CMDPTCS 668
G+ G +C T+ V+ C N GTC T C C G+ G+ C+ D C+ C+
Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCA 154
Query: 669 GRGVCV----RGECHCSVGWGGTNCETPRATC--LDQCSGHGTFL--PDTGLCSCDPSWT 720
C + C C G+ G CET C C GT L P + C C +T
Sbjct: 155 NGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFT 214
Query: 721 GHDCSIEICAADCGGHGVCVGGTCR----------CEDGWMGAACDQRA--C-HPRCAEH 767
G C + C GGTCR C G+ G+ C++ C + RC
Sbjct: 215 GQYC--DSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNG 272
Query: 768 GTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQL 823
G C DG C C P W G+ CT +D + + P C G C G+ CVC
Sbjct: 273 GVCVDGVNTYNCRCPPQWTGQFCT--EDVDECLLQ--PNACQNGGTCANRNGGYGCVCVN 328
Query: 824 GWRGAGCDTSMETACGDSKDNDGDGLVD------CMDPDCCLQPLCHINPLCLGSPNPLD 877
GW G C +++ C + G +D CM P+ LCH++ C+ +P
Sbjct: 329 GWSGDDCSENIDD-CAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKG 387
Query: 878 IIQETQVPVSQQNLHSFYDRIKFLVGRDSTHIIPGENPFDGGHACVIRGQVMTSDG 933
+ +T P++ Q + + K G D T + E + C G+ + +DG
Sbjct: 388 ALCDTN-PLNGQYICTCPQGYK---GADCTEDV-DECAMANSNPCEHAGKCVNTDG 438
Score = 127 bits (319), Expect = 2e-28
Identities = 98/366 (26%), Positives = 136/366 (37%), Gaps = 77/366 (21%)
Query: 561 ESVDNCP----SNCYGNGDCISGT----CHCFLGFLGP-------DCGRASCPVLCSGNG 605
E VD C + C G C++ C C G+ GP +C C +
Sbjct: 414 EDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLD 473
Query: 606 QYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESC--EE 659
+ CLC G+KG C++ N+C C N+G C+ C+C PG+ G C +
Sbjct: 474 KIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI 533
Query: 660 VDCMDPTCSGRGVCVRG----ECHCSVGWGGTNCETPRATCLDQCSGHGTFLP--DTGLC 713
DC C C+ EC C+ G+ G CE C HG D+ C
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTC 593
Query: 714 SCDPSWTGHDCSIEI---CAADCGGHGVCV----GGTCRCEDGWMGAACDQR--ACHPRC 764
C+P + G CS +I ++ C G C+ G C C+ G G C+ C
Sbjct: 594 ICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP 653
Query: 765 AEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGC---PGLCNG----------- 806
HG C DG C CSPG+ G+ C I +D C NG
Sbjct: 654 CIHGICMDGINRYSCVCSPGFTGQRCNID--IDECASNPCRKGATCINGVNGFRCICPEG 711
Query: 807 -------------------NGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG- 846
+G CT L+G+ C+C GW G C+ + N G
Sbjct: 712 PHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGT 771
Query: 847 -DGLVD 851
D LV+
Sbjct: 772 CDNLVN 777
Score = 126 bits (317), Expect = 3e-28
Identities = 108/360 (30%), Positives = 142/360 (39%), Gaps = 71/360 (19%)
Query: 560 IESVDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRASCPVLCSGNGQYMKG---- 610
+ ++ C S+ C G C+ G C C LG+ G +C + LCS + KG
Sbjct: 1023 LHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNC--QTLVNLCSRSPCKNKGTCVQ 1080
Query: 611 -----RCLCHSGWKGAECDVPTNQC----------IDVACSNHGTCI----TGTCICNPG 651
+CLC SGW GA CDVP C ++ C + G CI T C C G
Sbjct: 1081 KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLG 1140
Query: 652 YKGESCEEV--DCMDPTCSGRGVC---VRG-ECHCSVGWGGTNCETPRATCLDQ-CSGHG 704
Y G CEE +C C C + G C C G+ G NCE C +Q C G
Sbjct: 1141 YTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGG 1200
Query: 705 TF--LPDTGLCSCDPSWTGHDC--SIEICA--ADCGGHGVCV----GGTCRCEDGWMGAA 754
T L + CSC P G C +I+ CA C G C+ G +CRC G+ G
Sbjct: 1201 TCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGER 1260
Query: 755 CD---QRACHPRCAEHGT------CRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGL-C 804
C+ C+ G+ D C C + G HC + CP + C
Sbjct: 1261 CEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHC-------ETFVDVCPQMPC 1313
Query: 805 NGNGRCTLDLN---GWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
G C + N G+ C C G+ GA C +S CG K G+ V C P
Sbjct: 1314 LNGGTCAVASNMPDGFICRCPPGFSGARCQSS----CGQVKCRKGEQCVHTASGPRCFCP 1369
Score = 122 bits (306), Expect = 5e-27
Identities = 102/367 (27%), Positives = 147/367 (40%), Gaps = 79/367 (21%)
Query: 570 CYGNGDCISGTCH-----------------CFLGFLGPDCGRA--SCPVLCSGNGQYMKG 610
C+ + CIS CH C G+ G DC C + + N G
Sbjct: 373 CHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDEC-AMANSNPCEHAG 431
Query: 611 RCL---------CHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESC 657
+C+ C G+ G C++ N+C C N TC+ TC+C PG+KG C
Sbjct: 432 KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHC 491
Query: 658 E-EV-DCMDPTCSGRGVCV----RGECHCSVGWGGTNCE--------TP---RATCLDQC 700
E E+ +C C G CV R +C C G+ G C+ TP A C+D
Sbjct: 492 ELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHP 551
Query: 701 SGHGTFLPDTGLCSCDPSWTGHDC--SIEICAADCGGHGVCVGG----TCRCEDGWMGAA 754
+G+ C C +TG C +I+ C D HG C G TC C G+MGA
Sbjct: 552 NGYE--------CQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAI 603
Query: 755 CDQRA--CHPR-CAEHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGN 807
C + C+ C G C D +C C PG +G +C I D C +
Sbjct: 604 CSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEIN--FDDCASNPCI-----H 656
Query: 808 GRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINP 867
G C +N + CVC G+ G C+ ++ C + G ++ ++ C+ P +P
Sbjct: 657 GICMDGINRYSCVCSPGFTGQRCNIDID-ECASNPCRKGATCINGVNGFRCICPEGPHHP 715
Query: 868 LCLGSPN 874
C N
Sbjct: 716 SCYSQVN 722
Score = 122 bits (305), Expect = 6e-27
Identities = 97/332 (29%), Positives = 132/332 (39%), Gaps = 55/332 (16%)
Query: 570 CYGNGDCI----SGTCHCFLGFLGPDCGR---ASCPVLCSGNGQYMKG----RCLCHSGW 618
C G C S TC C GF G C C G + G CLC G+
Sbjct: 958 CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Query: 619 KGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCEEVD--CMDPTCSGRGV 672
G+ C N+C C N GTC+ G C C GY G++C+ + C C +G
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGT 1077
Query: 673 CVR----GECHCSVGWGGTNCETPRATC-------------LDQCSGHGTFLPDTGLCSC 715
CV+ +C C GW G C+ P +C L Q SG +T C C
Sbjct: 1078 CVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQC 1137
Query: 716 DPSWTGHDC--SIEICAADCGGHGVC----VGG-TCRCEDGWMGAACDQRA--CHPR-CA 765
+TG C ++ CA++ HG +GG C C G+ G C+ C + C
Sbjct: 1138 PLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ 1197
Query: 766 EHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVC 821
GTC D KC C PG G C +D + P NG G+C + G+ C C
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLC--EENIDDCARG--PHCLNG-GQCMDRIGGYSCRC 1252
Query: 822 QLGWRGAGCDTSMETACGDSKDNDGDGLVDCM 853
G+ G C+ + S +G +DC+
Sbjct: 1253 LPGFAGERCEGDINECL--SNPCSSEGSLDCI 1282
Score = 119 bits (297), Expect = 5e-26
Identities = 102/365 (27%), Positives = 133/365 (36%), Gaps = 51/365 (13%)
Query: 534 LDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISG-----TCHCFLGFL 588
L+ G H+ + + + V F + D C S+ NG + +C C GF
Sbjct: 116 LNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKCLTGFT 175
Query: 589 GPDC----GRASCPVLCSGNGQYMK----GRCLCHSGWKGAECDVPTNQCIDVACSNHGT 640
G C P C G + +C C G+ G CD C C N GT
Sbjct: 176 GQKCETDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGT 235
Query: 641 C-----ITGTCICNPGYKGESCEEV--DCMDPTCSGRGVCVRG----ECHCSVGWGGTNC 689
C T C C PG++G +CE DC + C GVCV G C C W G C
Sbjct: 236 CRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295
Query: 690 ETPRATCLDQ---CSGHGTFLPDTGL--CSCDPSWTGHDCS--IEICA-ADCGGHGVCVG 741
CL Q C GT G C C W+G DCS I+ CA A C C+
Sbjct: 296 TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCID 355
Query: 742 G----TCRCEDGWMGA------ACDQRACHPRCAEHGTCRDGK--CECSPGWNGEHCTIA 789
+C C +G G AC CH +G+ C C G+ G CT
Sbjct: 356 RVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-- 413
Query: 790 HYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGL 849
+D C G+C +HC C G+ G C+ + D ND
Sbjct: 414 EDVDECAMANS-NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQND---- 468
Query: 850 VDCMD 854
C+D
Sbjct: 469 ATCLD 473
Score = 116 bits (291), Expect = 3e-25
Identities = 90/320 (28%), Positives = 129/320 (40%), Gaps = 54/320 (16%)
Query: 561 ESVDNCP-SNCYGNGDCI----SGTCHCFLGFLGPDCGRASCPV--------LCSGN--- 604
E++D+C ++C CI S +C C G G C + LC N
Sbjct: 337 ENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLN 396
Query: 605 GQYMKGRCLCHSGWKGAECDVPTNQCIDV---ACSNHGTCITGT----CICNPGYKGESC 657
GQY+ C C G+KGA+C ++C C + G C+ C C GY G C
Sbjct: 397 GQYI---CTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRC 453
Query: 658 EEV--DCMDPTCSGRGVCVRG----ECHCSVGWGGTNCETPRATCLDQ-CSGHGTFLPDT 710
E +C C C+ C C G+ G +CE C C +G +
Sbjct: 454 EMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKV 513
Query: 711 GL--CSCDPSWTGHDCSIEI---CAADCGGHGVCV----GGTCRCEDGWMGAACDQRA-- 759
C C P +TG C I+I + C C+ G C+C G+ G C++
Sbjct: 514 NRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDN 573
Query: 760 CHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLN 815
C P HG C+DG C C+PG+ G C+ + E C +GRC +N
Sbjct: 574 CDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQ------IDECYSSPCLNDGRCIDLVN 627
Query: 816 GWHCVCQLGWRGAGCDTSME 835
G+ C CQ G G C+ + +
Sbjct: 628 GYQCNCQPGTSGVNCEINFD 647
Score = 107 bits (266), Expect = 2e-22
Identities = 93/333 (27%), Positives = 127/333 (38%), Gaps = 56/333 (16%)
Query: 561 ESVDNC---PSNCYGNGDCISGT----CHCFLGFLGPDCGR-------ASCPVLCSGNGQ 606
E VD C P+ C G C + C C G+ G DC ASC + +
Sbjct: 297 EDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDR 356
Query: 607 YMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT------CICNPGYKGESC-EE 659
C+C G G C + + CI C C T C C GYKG C E+
Sbjct: 357 VASFSCMCPEGKAGLLCHLD-DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTED 415
Query: 660 VD----CMDPTCSGRGVCVRGE----CHCSVGWGGTNCETPRATC-LDQCSGHGTFLPDT 710
VD C G CV + C C G+ G CE C D C T L
Sbjct: 416 VDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKI 475
Query: 711 G--LCSCDPSWTGHDCSIEI--CAAD-CGGHGVCVGGT----CRCEDGWMGAAC----DQ 757
G C C P + G C +EI C ++ C +G CV C C G+ G C D
Sbjct: 476 GGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDD 535
Query: 758 RACHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLD 813
+ P C C D +C+C+ G+ G C + + P C+ +G+C
Sbjct: 536 CSSTP-CLNGAKCIDHPNGYECQCATGFTGVLC------EENIDNCDPDPCH-HGQCQDG 587
Query: 814 LNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG 846
++ + C+C G+ GA C ++ NDG
Sbjct: 588 IDSYTCICNPGYMGAICSDQIDECYSSPCLNDG 620
Score = 99.8 bits (247), Expect = 3e-20
Identities = 103/388 (26%), Positives = 140/388 (36%), Gaps = 121/388 (31%)
Query: 570 CYGNGDCISGT----CHCFLGFLGPDCGR-----ASCP----VLCSGNGQYMKG-RCLCH 615
C +G CI+ C C LG+ G C AS P CS ++ G RC C
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCS---DFIGGYRCECV 1176
Query: 616 SGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEV--DCM-DPTCS 668
G++G C+ ++C + C N GTCI C C PG +G CEE DC P C
Sbjct: 1177 PGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCL 1236
Query: 669 GRGVCVRG----ECHCSVGWGGTNCETPRATCLDQ-CSGHGTF----LPDTGLCSCDPSW 719
G C+ C C G+ G CE CL CS G+ L + LC C ++
Sbjct: 1237 NGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAF 1296
Query: 720 TGHDCS--IEICAA-DCGGHGVCV-------GGTCRCEDGWMGAACDQ------------ 757
TG C +++C C G C G CRC G+ GA C
Sbjct: 1297 TGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQ 1356
Query: 758 ---------------RACHPRCAEH-----GTCRDGK------CECSPGWNGEHC----- 786
R C CA G+C + C+C+P ++G C
Sbjct: 1357 CVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTA 1416
Query: 787 --------TIAHYLDRVVKEG-CPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMET- 836
++ Y ++G C CN + CQ W G C +ME
Sbjct: 1417 PPSTPPATCLSQYCADKARDGVCDEACNSH------------ACQ--WDGGDCSLTMENP 1462
Query: 837 --------ACGDSKDNDGDGL---VDCM 853
C D +N D L V+C+
Sbjct: 1463 WANCSSPLPCWDYINNQCDELCNTVECL 1490
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 139 bits (351), Expect = 3e-32
Identities = 104/342 (30%), Positives = 132/342 (38%), Gaps = 87/342 (25%)
Query: 570 CYGNGDCISGTCHCFLG----FLGP--DCGRASCPVL----CSGNGQYMKGRCLCHSGWK 619
C+G G C G C C + F GP +C C C+G+G+ G+C C GW
Sbjct: 63 CHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKCDCGKCKCDQGWY 122
Query: 620 GAECDVPTN-------------QCIDVACSNHGTCITGTCICNPG-------YKGESCEE 659
G C PTN D+ CSN GTC G C C+ K C++
Sbjct: 123 GDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDD 182
Query: 660 VDCMD----PTCSGRGVCVRGECHCSVGWGGTNCE-----TP-----RATCLDQ--CSGH 703
+C+D C G G C G C+C GW G CE TP R T D CS
Sbjct: 183 RECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNR 242
Query: 704 GTFLPDTGLCSC---DPSWTGHDCSIEICAAD---------------CGGHGVCVGGTCR 745
GT + G C+C DP+ D + C D C GHG C G C
Sbjct: 243 GTCV--CGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCD 300
Query: 746 CEDGWMGAACDQ------------RACHPR----CAEHGTCRDGKCEC-SPGWNGEHCTI 788
C+ GW G C+ R C C+ G C GKC C PG +
Sbjct: 301 CKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKT 360
Query: 789 AHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
DR ++ +C G+G C+ CVC+ GW G C
Sbjct: 361 CECDDRRCEDLDGVVCGGHGTCSCG----RCVCERGWFGKLC 398
Score = 135 bits (339), Expect = 7e-31
Identities = 102/349 (29%), Positives = 129/349 (36%), Gaps = 100/349 (28%)
Query: 570 CYGNGDCISGTCHC------------FLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSG 617
C G C G C C F +C +C G+G+ G C C +G
Sbjct: 151 CSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAG 210
Query: 618 WKGAECDVPTN--------QCIDV---ACSNHGTCITGTCICNP--------GYKGESCE 658
W G +C+ + +C CSN GTC+ G C C+ G++CE
Sbjct: 211 WHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCE 270
Query: 659 --EVDCM-------DPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLD----------- 698
E DC D CSG G C G C C GW G CE P++ L
Sbjct: 271 CDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGS 330
Query: 699 ---QCSGHGTFLPDTGLCSCDPSWT----GHDCSI------EICAADCGGHGVCVGGTCR 745
CSG G + G C+C P G C ++ CGGHG C G C
Sbjct: 331 SDLPCSGRGKC--ECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCV 388
Query: 746 CEDGWMGAACDQRACHPR--------------------CAEHGTCRDGKCECS-PGW--N 782
CE GW G C HPR C+ G+C GKC CS W +
Sbjct: 389 CERGWFGKLCQ----HPRKCNMTEEQSKNLCESADGILCSGKGSCHCGKCICSAEEWYIS 444
Query: 783 GEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD 831
GE C DR + +C GNG C+ +C C GW G C+
Sbjct: 445 GEFCDCD---DRDCDKHDGLICTGNGICSCG----NCECWDGWNGNACE 486
Score = 133 bits (334), Expect = 3e-30
Identities = 109/373 (29%), Positives = 132/373 (35%), Gaps = 102/373 (27%)
Query: 568 SNCYGNGDCISGTCHCFLGFLGPDCG----------------RASCPVLCSGNGQYMKGR 611
S C G+G C G C C G+ G C + S ++CS G GR
Sbjct: 102 STCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTCHCGR 161
Query: 612 CLCHSG-----WKGAECDVPTNQCID----VACSNHGTCITGTCICNPGYKGESCE---- 658
C C + G C+ +CID C HG C G C C G+ G+ CE
Sbjct: 162 CKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCD 221
Query: 659 ------EVDCMDP---TCSGRGVCVRGECHC-----SVGWG---GTNCETPRATCL---- 697
+ C P CS RG CV GEC C + WG G CE C
Sbjct: 222 ITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYD 281
Query: 698 ----DQCSGHGTFLPDTGLCSCDPSWTGHDC------------SIEICAAD----CGGHG 737
D CSGHG + G C C W G C SI C C G G
Sbjct: 282 RYSDDFCSGHGQC--NCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSSDLPCSGRG 339
Query: 738 VCVGGTCRCEDG------WMGAACDQRACHPR----CAEHGTCRDGKCECSPGWNGE--- 784
C G C C CD R C C HGTC G+C C GW G+
Sbjct: 340 KCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGKLCQ 399
Query: 785 ---HCTIAHYLDRVVKEGCPG-LCNGNGRCTLDLNGWHCVCQL-GW--RGAGCDTSMETA 837
C + + + E G LC+G G C + C+C W G CD
Sbjct: 400 HPRKCNMTEEQSKNLCESADGILCSGKGSC----HCGKCICSAEEWYISGEFCD------ 449
Query: 838 CGDSKDNDGDGLV 850
C D + DGL+
Sbjct: 450 CDDRDCDKHDGLI 462
Score = 118 bits (296), Expect = 7e-26
Identities = 92/302 (30%), Positives = 108/302 (35%), Gaps = 79/302 (26%)
Query: 564 DNCPSNCYGNGDCISGTCHCFLGFLGPDCG------------RASCP--VLCSGNGQYMK 609
D C G+G C G C+C G+ G C R + P +CS G +
Sbjct: 188 DETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVC 247
Query: 610 GRCLCHS-----GW---KGAECDVPTNQC-------IDVACSNHGTCITGTCICNPGYKG 654
G C CH W G C+ C D CS HG C G C C G+ G
Sbjct: 248 GECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYG 307
Query: 655 ESCEEVDCM---------------DPTCSGRGVCVRGECHCSVGWG----GTNCETPRAT 695
+ CE D CSGRG C G+C C G CE
Sbjct: 308 KKCEHPQSCTLSAEESIRKCQGSSDLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRR 367
Query: 696 CLDQ----CSGHGTFLPDTGLCSCDPSWTGHDC------------SIEIC-AAD---CGG 735
C D C GHGT G C C+ W G C S +C +AD C G
Sbjct: 368 CEDLDGVVCGGHGTC--SCGRCVCERGWFGKLCQHPRKCNMTEEQSKNLCESADGILCSG 425
Query: 736 HGVCVGGTCRCE-DGWMGAA----CDQRACHPR----CAEHGTCRDGKCECSPGWNGEHC 786
G C G C C + W + CD R C C +G C G CEC GWNG C
Sbjct: 426 KGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICSCGNCECWDGWNGNAC 485
Query: 787 TI 788
I
Sbjct: 486 EI 487
Score = 97.1 bits (240), Expect = 2e-19
Identities = 79/267 (29%), Positives = 98/267 (36%), Gaps = 64/267 (23%)
Query: 623 CDVPTNQCIDVACSNHGTCITGTCICN---PG-YKGESCE--EVDCMD---PTCSGRGVC 673
C P C G C G CIC+ PG + G CE E C TC+G G C
Sbjct: 51 CRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEWVCETYDGSTCAGHGKC 110
Query: 674 VRGECHCSVGWGGTNCETPRATCLDQ--------------CSGHGTFLPDTGLCSCDPSW 719
G+C C GW G C+ P L + CS GT G C CD S
Sbjct: 111 DCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNAGTC--HCGRCKCDNSD 168
Query: 720 TGH-------DCSIEICAAD-----CGGHGVCVGGTCRCEDGWMGAACD----------Q 757
+C C D CGGHG C G C C+ GW G C+ +
Sbjct: 169 GSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDKCEFQCDITPWESK 228
Query: 758 RACHPR----CAEHGTCRDGKCEC-----SPGWNGEHCTIAHYLDR----VVKEGCPGLC 804
R C C+ GTC G+C C + W H +R V C
Sbjct: 229 RRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERDCRAVYDRYSDDFC 288
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGCD 831
+G+G+C N C C+ GW G C+
Sbjct: 289 SGHGQC----NCGRCDCKAGWYGKKCE 311
Score = 73.6 bits (179), Expect = 3e-12
Identities = 58/223 (26%), Positives = 83/223 (37%), Gaps = 46/223 (20%)
Query: 684 WGGTNCETPRATCLDQCSG----------HGTFLPDTGLCSCDPSWTGH------DCSIE 727
W G C RA +C HG D G+C C + G +C
Sbjct: 35 WPGAACRLSRAESERRCRAPGQPPGAALCHGRGRCDCGVCICHVTEPGMFFGPLCECHEW 94
Query: 728 IC----AADCGGHGVCVGGTCRCEDGWMGAAC------------DQRACHPR----CAEH 767
+C + C GHG C G C+C+ GW G AC + C C+
Sbjct: 95 VCETYDGSTCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKSNQMCKNSQDIICSNA 154
Query: 768 GTCRDGKCEC--SPGWNGEHCTIAHYLDR-VVKEGCPGLCNGNGRCTLDLNGWHCVCQLG 824
GTC G+C+C S G + DR + + +C G+G+C +C C+ G
Sbjct: 155 GTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCG----NCYCKAG 210
Query: 825 WRGAGCDTSMETACGDSKD--NDGDGLVDCMDPDC-CLQPLCH 864
W G C+ + +SK DG + C C + CH
Sbjct: 211 WHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCH 253
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 139 bits (349), Expect = 5e-32
Identities = 94/273 (34%), Positives = 114/273 (41%), Gaps = 41/273 (15%)
Query: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPTCSGR 670
C C G+ G+ C T C D C NHG CI C C PG+ G +C+E C +P C
Sbjct: 1314 CKCKPGYIGSNCQ--TALC-DPDCKNHGKCIKPNICQCLPGHGGATCDEEHC-NPPCQHG 1369
Query: 671 GVCVRGE-CHCSVGWGGTNCETPRATCLDQCSGHGTFL-PDTGLCSCDPSWTGHDCSIEI 728
G C+ G C C G+ G CET C C G L PD +C C P W G CS +
Sbjct: 1370 GTCLAGNLCTCPYGFVGPRCET--MVCNRHCENGGQCLTPD--ICQCKPGWYGPTCSTAL 1425
Query: 729 CAADCGGHGVC-VGGTCRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHC 786
C C G C TC C +G+ G C CHP C G C R+ C C G+ G
Sbjct: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGR-- 1483
Query: 787 TIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG 846
R K C C G+C + C C GW G C+T + C N G
Sbjct: 1484 -------RFQKSICDPTCMNGGKC---VGPSTCSCPSGWSGKRCNTPI---CLQKCKNGG 1530
Query: 847 DGLVDCMDPDCCLQP------LCHI---NPLCL 870
+C+ P C P C I NP CL
Sbjct: 1531 ----ECIAPSICHCPSSWEGVRCQIPICNPKCL 1559
Score = 129 bits (323), Expect = 5e-29
Identities = 76/230 (33%), Positives = 100/230 (43%), Gaps = 15/230 (6%)
Query: 564 DNCPSNCYGNGDCISGT-CHCFLGFLGPDCGRASCPVLCSGNGQYMKGR-CLCHSGWKGA 621
++C C G C++G C C GF+GP C C C GQ + C C GW G
Sbjct: 1360 EHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGP 1419
Query: 622 ECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGE-CH 679
C T C D C N G+C TC+C G+ GE C+ C P C G C+R C
Sbjct: 1420 TCS--TALC-DPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFC-HPPCKNGGHCMRNNVCV 1475
Query: 680 CSVGWGGTNCETPRATCLDQCSGHGTFL-PDTGLCSCDPSWTGHDCSIEICAADCGGHGV 738
C G+ G + ++ C C G + P T CSC W+G C+ IC C G
Sbjct: 1476 CREGYTGRRFQ--KSICDPTCMNGGKCVGPST--CSCPSGWSGKRCNTPICLQKCKNGGE 1531
Query: 739 CVGGT-CRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHC 786
C+ + C C W G C C+P+C G C C C ++G C
Sbjct: 1532 CIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKC 1581
Score = 99.8 bits (247), Expect = 3e-20
Identities = 92/332 (27%), Positives = 125/332 (37%), Gaps = 64/332 (19%)
Query: 545 NDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGT----------CHCFLGFLGPDC-- 592
ND ++E + ++S D C G C+S C C GF G C
Sbjct: 1163 NDDCDAETRVTIEVTVKSCD-----CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEV 1217
Query: 593 GRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGY 652
+ C G G Y+ SG+ CD P ++ N T T T +
Sbjct: 1218 DISGCQSNPCGLGSYI-------SGFHSYSCDCPPELKVETQFVNQFT--TQTVVLTRSD 1268
Query: 653 KGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGL 712
K + EE D GR V+ + G T C+ P G +
Sbjct: 1269 KSVNKEEDD---KNAQGRKRHVKP----TSGNAFTICKYP--------CGKSRECVAPNI 1313
Query: 713 CSCDPSWTGHDCSIEICAADCGGHGVCV-GGTCRCEDGWMGAACDQRACHPRCAEHGTCR 771
C C P + G +C +C DC HG C+ C+C G GA CD+ C+P C GTC
Sbjct: 1314 CKCKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTCL 1373
Query: 772 DGK-CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRC-TLDLNGWHCVCQLGWRGAG 829
G C C G+ G C + +V C C G+C T D+ C C+ GW G
Sbjct: 1374 AGNLCTCPYGFVGPRC------ETMV---CNRHCENGGQCLTPDI----CQCKPGWYGPT 1420
Query: 830 CDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
C T++ C N G C P+ CL P
Sbjct: 1421 CSTAL---CDPVCLNGG----SCNKPNTCLCP 1445
Score = 84.7 bits (208), Expect = 1e-15
Identities = 51/167 (30%), Positives = 66/167 (39%), Gaps = 11/167 (6%)
Query: 566 CPSNCYGNGDCIS-GTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGR-CLCHSGWKGAEC 623
C C G C TC C GF G C A C C G M+ C+C G+ G
Sbjct: 1426 CDPVCLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRF 1485
Query: 624 DVPTNQCIDVACSNHGTCI-TGTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGE-CHCS 681
D C N G C+ TC C G+ G+ C C+ C G C+ CHC
Sbjct: 1486 Q---KSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQK-CKNGGECIAPSICHCP 1541
Query: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEI 728
W G C+ P C +C G + +CSC ++G C +I
Sbjct: 1542 SSWEGVRCQIP--ICNPKCLYGGRCI-FPNVCSCRTEYSGVKCEKKI 1585
Score = 35.4 bits (80), Expect = 0.79
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 597 CPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVA-CSNHGTC 641
CP LCSGNGQ M+ C C + +C ++ ++ N G C
Sbjct: 890 CPNLCSGNGQCMEWGCACSPSFSSYDCSDSYDKAPEITELGNAGFC 935
Score = 34.3 bits (77), Expect = 1.8
Identities = 15/33 (45%), Positives = 17/33 (51%)
Query: 560 IESVDNCPSNCYGNGDCISGTCHCFLGFLGPDC 592
I SV CP+ C GNG C+ C C F DC
Sbjct: 884 ILSVLKCPNLCSGNGQCMEWGCACSPSFSSYDC 916
Score = 34.3 bits (77), Expect = 1.8
Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 4/38 (10%)
Query: 800 CPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETA 837
CP LC+GNG+C W C C + C S + A
Sbjct: 890 CPNLCSGNGQCM----EWGCACSPSFSSYDCSDSYDKA 923
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 139 bits (349), Expect = 5e-32
Identities = 96/319 (30%), Positives = 125/319 (39%), Gaps = 67/319 (21%)
Query: 578 SGTCHCFLGFLGPDCGRASCPVLCSGNGQYMK--GRCLCHSGWKGAECD--VPTNQCIDV 633
+G C G++GP+C RA C CS K G C C GW+G CD +P C+
Sbjct: 215 NGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHG 274
Query: 634 ACS------------------------NHGTCITG-----------TCICNPGYKGESCE 658
C+ H C+ G C C GY G +CE
Sbjct: 275 ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE 334
Query: 659 --EVDCMDPTCSGRGVC----VRGECHCSVGWGGTNCETPRATCL-DQCSGHGTF--LPD 709
E C+ C RG C + EC CS GW G C T C + CS GT L +
Sbjct: 335 IAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVN 394
Query: 710 TGLCSCDPSWTGHDCSI---EICAADCGGHGVC----VGGTCRCEDGWMGAACDQRA--C 760
C C P WTG C + E A C C C C GWMG CD C
Sbjct: 395 GFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC 454
Query: 761 HPRCAEHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNG 816
+C +CRD +C C PG+ G+HC +R + E C G C ++N
Sbjct: 455 LGQCQNDASCRDLVNGYRCICPPGYAGDHC------ERDIDECASNPCLNGGHCQNEINR 508
Query: 817 WHCVCQLGWRGAGCDTSME 835
+ C+C G+ G C ++
Sbjct: 509 FQCLCPTGFSGNLCQLDID 527
Score = 134 bits (336), Expect = 2e-30
Identities = 97/310 (31%), Positives = 120/310 (38%), Gaps = 43/310 (13%)
Query: 557 TTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHS 616
TT E +D+C N D G + GP C G K C C+
Sbjct: 569 TTPCEVIDSCTVAMASN-DTPEGVRYISSNVCGP---HGKCKSQSGG-----KFTCDCNK 619
Query: 617 GWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEV--DCMDPTCSGR 670
G+ G C N C C N GTCI G CIC+ G++G CE DC C
Sbjct: 620 GFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNG 679
Query: 671 GVCVR----GECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTG---LCSCDPSWTGHD 723
G C C C GW G C + + C + +G D G C C W G
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTT 739
Query: 724 CSI---EICAAD-CGGHGVCVGG----TCRCEDGWMGAACDQRA--CHPR-CAEHGTCRD 772
C+I C + C G CV TC C++GW G C Q C P C GTC D
Sbjct: 740 CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVD 799
Query: 773 G----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGA 828
G +CEC+PG+ G C I + E C C ++NG+ CVC G GA
Sbjct: 800 GDNWYRCECAPGFAGPDCRIN------INECQSSPCAFGATCVDEINGYRCVCPPGHSGA 853
Query: 829 GCDTSMETAC 838
C C
Sbjct: 854 KCQEVSGRPC 863
Score = 118 bits (295), Expect = 9e-26
Identities = 95/352 (26%), Positives = 139/352 (39%), Gaps = 56/352 (15%)
Query: 562 SVDNCPSNCYGNGDC---ISG-TCHCFLGFLGPDCGR-----ASCPVLCSGNGQYMKGR- 611
++++C C + C ++G C C G+ G C R AS P L G+ Q R
Sbjct: 450 NINDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRF 509
Query: 612 -CLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEVD--CMD 664
CLC +G+ G C + + C C N C C C Y+G++C + C
Sbjct: 510 QCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRT 569
Query: 665 PTCSGRGVCV----RGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWT 720
C C + V + +N P C Q G T C C+ +T
Sbjct: 570 TPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFT-------CDCNKGFT 622
Query: 721 GHDC--SIEICAAD-CGGHGVCVGGT----CRCEDGWMGAACD-------QRACHPRCAE 766
G C +I C ++ C G C+ G C C DGW GA C+ Q CH
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCH----N 678
Query: 767 HGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQ 822
GTCRD C+C GW G+ C H D E CN G C + + + C+C
Sbjct: 679 GGTCRDLVNDFYCDCKNGWKGKTC---HSRDSQCDEAT---CNNGGTCYDEGDAFKCMCP 732
Query: 823 LGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPN 874
GW G C+ + ++C + ++G V + C+ P+C + N
Sbjct: 733 GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTN 784
Score = 102 bits (255), Expect = 4e-21
Identities = 83/281 (29%), Positives = 108/281 (38%), Gaps = 54/281 (19%)
Query: 561 ESVDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCL-- 613
E++++C SN C G CI G C C G+ G C CS N + G C
Sbjct: 628 ENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIND--CSQNPCHNGGTCRDL 685
Query: 614 -------CHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE---E 659
C +GWKG C +QC + C+N GTC C+C G++G +C
Sbjct: 686 VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARN 745
Query: 660 VDCMDPTCSGRGVCV-RGE---CHCSVGWGGTNCETPRATCLDQ-CSGHGTFLPDTGL-- 712
C+ C G CV GE C C GW G C C C GT +
Sbjct: 746 SSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYR 805
Query: 713 CSCDPSWTGHDCSIEI--C-AADCGGHGVCV----GGTCRCEDGWMGAACDQRACHPRCA 765
C C P + G DC I I C ++ C CV G C C G GA C + + P C
Sbjct: 806 CECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRP-CI 864
Query: 766 EHGT----------------CRDGKCECSPGWNGEHCTIAH 790
G+ C +G+ CS W G + H
Sbjct: 865 TMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLH 905
Score = 84.7 bits (208), Expect = 1e-15
Identities = 68/228 (29%), Positives = 90/228 (39%), Gaps = 27/228 (11%)
Query: 648 CNPGYKGESCEEVDCMDPTCSGRGVCVR-GECHCSVGWGGTNCETPRATCLDQCSG-HGT 705
C+ Y G C + G C + G C GW G C RA C CS HG+
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECN--RAICRQGCSPKHGS 244
Query: 706 F-LPDTGLCSCDPSWTGHDCSIEICAADCGGHGVC-VGGTCRCEDGWMGAACDQR----A 759
LP G C C W G C I C HG+C C CE W G CD+
Sbjct: 245 CKLP--GDCRCQYGWQGLYCDKCIPHPGCV-HGICNEPWQCLCETNWGGQLCDKDLNYCG 301
Query: 760 CHPRCAEHGTCRDG-----KCECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGNGRCTLD 813
H C GTC + +C C G++G +C IA + C C+ G C
Sbjct: 302 THQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEH-------ACLSDPCHNRGSCKET 354
Query: 814 LNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
G+ C C GW G C T+++ C + + G D ++ C+ P
Sbjct: 355 SLGFECECSPGWTGPTCSTNIDD-CSPNNCSHGGTCQDLVNGFKCVCP 401
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 137 bits (346), Expect = 1e-31
Identities = 95/327 (29%), Positives = 137/327 (41%), Gaps = 47/327 (14%)
Query: 571 YGNGDCISGTCHCFLGFLGPDCGRASCPVLCS--GNGQYMKGRCLCHSGWKGAECDVPTN 628
YGN C+ G ++G +C A C C+ G + G C C GW+G CD
Sbjct: 226 YGNKACMDG-------WMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD---- 274
Query: 629 QCIDVACSNHGTCI-TGTCICNPGYKGESCEE---VDCMDPTCSGRGVCVRGE-----CH 679
+C+ HG+C+ C C + G C++ C+ G C+ E C
Sbjct: 275 ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCT 334
Query: 680 CSVGWGGTNCETPRATCL-DQCSGHGTF--LPDTGLCSCDPSWTGHDCSIEI--CAAD-C 733
C G+ G NCE C + C+ G+ +P C C W+G C+++I CA++ C
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 734 GGHGVCV----GGTCRCEDGWMGAAC--DQRACHPR-CAEHGTCRD----GKCECSPGWN 782
G CV G C C + W+GA C D C + C +C++ C+C PGW
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWK 454
Query: 783 GEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSK 842
G +C + C G C G C +NG+ CVC G+ G C+ + C S
Sbjct: 455 GINC-------HINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERD-ECASSP 506
Query: 843 DNDGDGLVDCMDPDCCLQPLCHINPLC 869
+ G D D C P PLC
Sbjct: 507 CHSGGLCEDLADGFHCHCPQGFSGPLC 533
Score = 133 bits (335), Expect = 2e-30
Identities = 106/364 (29%), Positives = 139/364 (38%), Gaps = 58/364 (15%)
Query: 576 CISGTCHCFLGF---LGPDCGRASCPVLCSGNGQYMKG-----RCLCHSGWKGAECDVPT 627
C G C G GP + +C +G+ + C+C SG+ G C
Sbjct: 578 CPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 637
Query: 628 NQCIDVACSNHGTCITGT----CICNPGYKGESCEEV--DCMDPTCSGRGVCVR----GE 677
+ C+ C N GTCI C C G++GE C+ DC+ C RG C
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 697
Query: 678 CHCSVGWGGTNCETPRATC-LDQCSGHGTFLP--DTGLCSCDPSWTGHDCSI---EICAA 731
C C GW G C + C CS GT DT C+C P W G C++ C
Sbjct: 698 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP 757
Query: 732 D-CGGHGVCVGG----TCRCEDGWMGAACDQRA--CHPR-CAEHGTCRDG----KCECSP 779
+ C G CVG +C C DGW G C C+P C G C DG +CEC+P
Sbjct: 758 NPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAP 817
Query: 780 GWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD--TSMETA 837
G+ G C I + E C C ++NG+ C C G G C +
Sbjct: 818 GFAGPDCRIN------IDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 871
Query: 838 C---GDSKDNDGDGLVDCMDPDC------CLQPLCHINP-LCLGSPNPLDIIQETQVPVS 887
C G + + DC C C + C P L G P L Q P+
Sbjct: 872 CWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEAL----SAQCPLG 927
Query: 888 QQNL 891
Q+ L
Sbjct: 928 QRCL 931
Score = 120 bits (302), Expect = 1e-26
Identities = 111/395 (28%), Positives = 143/395 (36%), Gaps = 93/395 (23%)
Query: 558 TAIESVDNCPSN-CYGNGDCISGT----CHCFLGFLGPDC-------------GRASCPV 599
T +D C SN C G C+ C C ++G C SC
Sbjct: 381 TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKN 440
Query: 600 LCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGE 655
L G C C GWKG C + N C C + GTC + G C+C G+ G
Sbjct: 441 LIGGY------YCDCIPGWKGINCHINVNDCRG-QCQHGGTCKDLVNGYQCVCPRGFGGR 493
Query: 656 SCE--EVDCMDPTCSGRGVCVR----GECHCSVGWGGTNCETPRATCLDQCSGHGTF--- 706
CE +C C G+C CHC G+ G CE C +G
Sbjct: 494 HCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYN 553
Query: 707 LPDTGLCSCDPSWTGHDCS-------------IEICAAD-------------CGGHGVCV 740
L C+C + G +CS I+ C +D CG HG CV
Sbjct: 554 LEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCV 613
Query: 741 ---GG--TCRCEDGWMGAACDQR---ACHPRCAEHGTCRDG----KCECSPGWNGEHCTI 788
GG +C C+ G+ G C + C GTC D +C C GW GE C
Sbjct: 614 SQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC-- 671
Query: 789 AHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDG 848
D + P C+ GRC +N ++C C GW+G C S E C ++G
Sbjct: 672 ----DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH-SREFQCDAYTCSNGGT 726
Query: 849 LVDCMDPDCCLQP------LCHI--NPLCLGSPNP 875
D D C P C + N CL PNP
Sbjct: 727 CYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNP 759
Score = 112 bits (280), Expect = 5e-24
Identities = 101/368 (27%), Positives = 141/368 (38%), Gaps = 66/368 (17%)
Query: 570 CYGNGDCISGT-----CHCFLGFLGPDCGRA--SCPVLCSGNG----QYMKG-RCLCHSG 617
C G CI+ C C G+ G +C +A +C NG + G C C SG
Sbjct: 317 CTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 618 WKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESC--EEVDCMDPTCSGRG 671
W G C + ++C C+ GTC+ CIC + G +C + +C C
Sbjct: 377 WSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAF 436
Query: 672 VC---VRG-ECHCSVGWGGTNCETPRATCLDQCSGHGTF--LPDTGLCSCDPSWTGHDCS 725
C + G C C GW G NC C QC GT L + C C + G C
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 496
Query: 726 I---EICAADCGGHGVCV----GGTCRCEDGWMGAAC--DQRACHPR-CAEHGTC----R 771
+ E ++ C G+C G C C G+ G C D C P C C
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556
Query: 772 DGKCECSPGWNGEHCTIAHY-----LDRVVKEGC-------------PGLCNGNGRCTLD 813
D C C + G++C++ RV+ +GC G+C +GRC
Sbjct: 557 DYYCACPDDFGGKNCSVPREPCPGGACRVI-DGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 814 LNG-WHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP------LCHIN 866
G + C+C G+ G C +++ G N G +D +D C P LC N
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT-CIDEVDAFRCFCPSGWEGELCDTN 674
Query: 867 PL-CLGSP 873
P CL P
Sbjct: 675 PNDCLPDP 682
Score = 109 bits (272), Expect = 4e-23
Identities = 93/308 (30%), Positives = 107/308 (34%), Gaps = 62/308 (20%)
Query: 564 DNCPSN-CYGNGDCISGT----CHCFLGFLGPDC-------------GRASCPVLCSGNG 605
D C S+ C+ G C CHC GF GP C A C L G
Sbjct: 500 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNL---EG 556
Query: 606 QYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEVDCMDP 665
Y C C + G C VP C AC C + PG G + V
Sbjct: 557 DYY---CACPDDFGGKNCSVPREPCPGGACRVIDGCGSDA---GPGMPGTAASGV----- 605
Query: 666 TCSGRGVCVRG-----ECHCSVGWGGTNCETPRATCLDQ-CSGHGTFLP--DTGLCSCDP 717
C G CV C C G+ GT C CL Q C GT + D C C
Sbjct: 606 -CGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPS 664
Query: 718 SWTGHDCSIEI--CAAD-CGGHGVCVGGT----CRCEDGWMGAACDQRA--CHP-RCAEH 767
W G C C D C G C C C+DGW G C R C C+
Sbjct: 665 GWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNG 724
Query: 768 GTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGNGRCTLDLNGWHCVCQ 822
GTC D +C C PGW G C +A C P C G C + C+C+
Sbjct: 725 GTCYDSGDTFRCACPPGWKGSTCAVAK------NSSCLPNPCVNGGTCVGSGASFSCICR 778
Query: 823 LGWRGAGC 830
GW G C
Sbjct: 779 DGWEGRTC 786
Score = 100 bits (248), Expect = 3e-20
Identities = 73/245 (29%), Positives = 101/245 (41%), Gaps = 44/245 (17%)
Query: 611 RCLCHSGWKGAECDV---PTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPT 666
R C + A C+ P N H TC G C G+ G+ C+E C
Sbjct: 195 RVRCDENYYSATCNKFCRPRNDFF-----GHYTCDQYGNKACMDGWMGKECKEAVCKQGC 249
Query: 667 CSGRGVC-VRGECHCSVGWGGTNCE--TPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHD 723
G C V GEC CS GW G C+ P C+ HG+ + + C+C+ +W G
Sbjct: 250 NLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCV-----HGSCV-EPWQCNCETNWGGLL 303
Query: 724 CSIEICAADCGGHGVCV-GGT----------CRCEDGWMGAACD--QRACHPR-CAEHGT 769
C ++ CG H C GGT C C DG+ G C+ + AC CA G+
Sbjct: 304 CDKDL--NYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGS 361
Query: 770 CRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGW 825
C + +C C GW+G C + + E C G C ++G+ C+C W
Sbjct: 362 CHEVPSGFECHCPSGWSGPTCALD------IDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 826 RGAGC 830
GA C
Sbjct: 416 VGATC 420
Score = 71.6 bits (174), Expect = 1e-11
Identities = 53/186 (28%), Positives = 71/186 (38%), Gaps = 18/186 (9%)
Query: 694 ATCLDQCSGHGTFL-----PDTGLCSCDPSWTGHDCSIEICAADCGG-HGVC-VGGTCRC 746
ATC C F G +C W G +C +C C HG C V G CRC
Sbjct: 205 ATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRC 264
Query: 747 EDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHCTIAHYLDRVVKE-GCPGLC 804
GW G CD+ +P C HG+C +C C W G C D+ + G C
Sbjct: 265 SYGWQGRFCDECVPYPGCV-HGSCVEPWQCNCETNWGGLLC------DKDLNYCGSHHPC 317
Query: 805 NGNGRC-TLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLC 863
G C + + + C C G+ G C+ + E AC + +G + C P
Sbjct: 318 TNGGTCINAEPDQYRCTCPDGYSGRNCEKA-EHACTSNPCANGGSCHEVPSGFECHCPSG 376
Query: 864 HINPLC 869
P C
Sbjct: 377 WSGPTC 382
Score = 68.9 bits (167), Expect = 6e-11
Identities = 46/141 (32%), Positives = 58/141 (41%), Gaps = 24/141 (17%)
Query: 570 CYGNGDCISGTCHCFLGFLGPDCGRA---SC---PVL----CSGNGQYMKGRCLCHSGWK 619
CY +GD C C G+ G C A SC P + C G+G C+C GW+
Sbjct: 727 CYDSGDTFR--CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS--CICRDGWE 782
Query: 620 GAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCE-EVD-CMDPTCSGRGVC 673
G C TN C + C N G C+ G C C PG+ G C +D C C+ C
Sbjct: 783 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATC 842
Query: 674 VRG----ECHCSVGWGGTNCE 690
V C C G G C+
Sbjct: 843 VDEINGYRCSCPPGRAGPRCQ 863
Score = 58.9 bits (141), Expect = 7e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 32/162 (19%)
Query: 557 TTAIESVDNC-PSNCYGNGDCI----SGTCHCFLGFLGPDCGRAS--C-PVLCSGNGQYM 608
T A+ +C P+ C G C+ S +C C G+ G C + C P+ C G +
Sbjct: 746 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 805
Query: 609 KG----RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEV 660
G RC C G+ G +C + ++C C+ TC+ C C PG G C+EV
Sbjct: 806 DGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEV 865
Query: 661 DCMDPTCSGRGV----------------CVRGECHCSVGWGG 686
+C RG C+ G CS W G
Sbjct: 866 IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCG 907
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 137 bits (345), Expect = 1e-31
Identities = 98/356 (27%), Positives = 138/356 (38%), Gaps = 47/356 (13%)
Query: 562 SVDNCPSN-CYGNGDCISG----TCHCFLGFLGPDCGRA-----SCPVLCSGNGQYMKG- 610
++D C N C+ G C G TC C G+ P C S P + + G
Sbjct: 678 NIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGY 737
Query: 611 RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEE--VDCMD 664
+C C GW G CD+ N+C C N GTC T C C G+ G +C+ +C
Sbjct: 738 KCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECAS 797
Query: 665 PTCSGRGVCVRG----ECHCSVGWGGTNCETPRATCL-DQCSGHGTFLP----DTGLCSC 715
C +G C+ +C+C + + G CE A C C G ++ C C
Sbjct: 798 NPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVC 857
Query: 716 DPSWTGHDCSIEI--CAADCGGHGVCVGGT-----CRCEDGWMGAAC--DQRACHPR-CA 765
W G C ++I C HG T C C+ G+ G C D C P C
Sbjct: 858 PTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCH 917
Query: 766 EHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVC 821
G+C DG C+C PG+ G C + + E C CT ++ + C C
Sbjct: 918 NGGSCTDGINTAFCDCLPGFRGTFC------EEDINECASDPCRNGANCTDCVDSYTCTC 971
Query: 822 QLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPNPLD 877
G+ G C+ + C +S +G VD ++ CL P C N D
Sbjct: 972 PAGFSGIHCENNTPD-CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECD 1026
Score = 133 bits (334), Expect = 3e-30
Identities = 94/342 (27%), Positives = 136/342 (39%), Gaps = 43/342 (12%)
Query: 568 SNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCL---------CHSGW 618
SNC N C C G+ GP C + N G+C+ C G+
Sbjct: 385 SNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGY 444
Query: 619 KGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE--EVDCMDPTCSGRGV 672
G C++ N+C+ C N TC+ CIC PGY+G CE +C C G
Sbjct: 445 TGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGR 504
Query: 673 CV----RGECHCSVGWGGTNCETPRATCLDQCSGHGTFL---PDTGLCSCDPSWTGHDCS 725
C+ +C C G+ G C+ C +G P+T C C +TG C
Sbjct: 505 CLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Query: 726 IEI--CAADCGGHGVCVGG----TCRCEDGWMGAACD---QRACHPRCAEHGTCRDGK-- 774
++I C D +G C G TC C G+ G C+ C GTC+D
Sbjct: 565 VDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNA 624
Query: 775 --CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDT 832
C C G G +C I LD C +G C ++G+ C C+ G+ G+ C+
Sbjct: 625 YLCFCLKGTTGPNCEI--NLDDCASSPC-----DSGTCLDKIDGYECACEPGYTGSMCNI 677
Query: 833 SMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSPN 874
+++ G+ N G D ++ C P + +P CL N
Sbjct: 678 NIDECAGNPCHNGGT-CEDGINGFTCRCPEGYHDPTCLSEVN 718
Score = 126 bits (317), Expect = 3e-28
Identities = 102/355 (28%), Positives = 137/355 (38%), Gaps = 56/355 (15%)
Query: 570 CYGNGDC--ISGT--CHCFLGFLGPDCGRA----SCPVLCSGNGQYMKGR------CLCH 615
C G C +GT C C F+GP C S P +G + R C C
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCA 90
Query: 616 SGWKGAECDVPT-NQCIDVACSNHGTCITGT-----CICNPGYKGESCEEVD-CMDPTCS 668
G+ G C P N C+ C N GTC T C C PG+ G+SC++ D C C+
Sbjct: 91 LGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCA 150
Query: 669 GRGVCVRGE----CHCSVGWGGTNCETPRATCLDQ---CSGHGTFLPDTGL--CSCDPSW 719
G C+ E CHC + G C C + C GT + G C C +
Sbjct: 151 NGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATH 210
Query: 720 TGHDCS---IEICAADCGGHGVC-----VGGTCRCEDGWMGAACDQRACH---PRCAEHG 768
TG +C + + C G C V C C G+ G C++ C G
Sbjct: 211 TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGG 270
Query: 769 TCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLG 824
C DG C C P W G++CT D + P C G C G++CVC G
Sbjct: 271 ACVDGVNTYNCRCPPEWTGQYCTE----DVDECQLMPNACQNGGTCHNTHGGYNCVCVNG 326
Query: 825 WRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP------LCHINPLCLGSP 873
W G C +++ C + G D + C P LCH+N C+ +P
Sbjct: 327 WTGEDCSENIDD-CASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
Score = 126 bits (317), Expect = 3e-28
Identities = 100/345 (28%), Positives = 135/345 (39%), Gaps = 67/345 (19%)
Query: 561 ESVDNCPSNCYGNG----DCI-SGTCHCFLGFLG-------PDCGRASCPVLCSGNGQYM 608
E ++ C S+ NG DC+ S TC C GF G PDC +SC G +
Sbjct: 944 EDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSC----FNGGTCV 999
Query: 609 KG----RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEV 660
G CLC G+ G+ C N+C C + GTC G C C GY G +C+ +
Sbjct: 1000 DGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNL 1059
Query: 661 D--CMDPTCSGRGVC----VRGECHCSVGWGGTNCETPRATC----------LDQCSGHG 704
C C G C + C C GW G C+ P +C + + HG
Sbjct: 1060 VHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHG 1119
Query: 705 TFLPDTGL---CSCDPSWTGHDCS--IEICA-ADCGGHGVCV----GGTCRCEDGWMGAA 754
D G C C +TG C ++ C+ + C C G +C+C G+ G
Sbjct: 1120 GLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVN 1179
Query: 755 C----DQRACHPRCAEHGTCRD----GKCECSPGWNGEHCTIA-----HYLDRVVKEGCP 801
C D+ HP C GTC D KC C G G HC I +D V +
Sbjct: 1180 CSEEIDECLSHP-CQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSP-- 1236
Query: 802 GLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG 846
C NG C + G+ C C G+ G C+ + + D G
Sbjct: 1237 -KCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARG 1280
Score = 117 bits (294), Expect = 1e-25
Identities = 89/318 (27%), Positives = 119/318 (37%), Gaps = 54/318 (16%)
Query: 581 CHCFLGFLGPDCGRA--SC-PVLCSGNGQYMKGR----CLCHSGWKGAECDVPTNQCIDV 633
CHC G+ G +C C P C G G C C G++G C+ N+C
Sbjct: 893 CHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASD 952
Query: 634 ACSNHGTCI----TGTCICNPGYKGESCEE--VDCMDPTCSGRGVCVRG----ECHCSVG 683
C N C + TC C G+ G CE DC + +C G CV G C C G
Sbjct: 953 PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPG 1012
Query: 684 WGGTNCETPRATCLDQCSGHGTFLPD---TGLCSCDPSWTGHDCS--IEIC-AADCGGHG 737
+ G+ C+ C Q HG D + C+C +TG +C + C ++ C G
Sbjct: 1013 FTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG 1072
Query: 738 VC----VGGTCRCEDGWMGAACD------------QRACHPRCAEHG-TCRDG----KCE 776
C C C GW G CD Q R +HG C D C
Sbjct: 1073 KCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCR 1132
Query: 777 CSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMET 836
C G+ G +C + +V E P C CT L G+ C C G+ G C ++
Sbjct: 1133 CQAGYTGSYC------EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDE 1186
Query: 837 ACGDSKDNDGDGLVDCMD 854
N G C+D
Sbjct: 1187 CLSHPCQNGG----TCLD 1200
Score = 115 bits (288), Expect = 6e-25
Identities = 107/438 (24%), Positives = 151/438 (34%), Gaps = 132/438 (30%)
Query: 561 ESVDNCPSN-CYGNGDCISG----TCHCFLGFLGPDCGR-----ASCPVLCSGNG----Q 606
E++D+CP N C G C+ G C C + G C P C G
Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
Query: 607 YMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTC---------------------ITGT 645
+ C+C +GW G +C + C AC + TC +
Sbjct: 316 HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375
Query: 646 CICNPGYKGESCE------EVDCMDPT--------------------CSGRGVCVRG--- 676
CI NP +G +C+ + C P+ C G C+
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
Query: 677 -ECHCSVGWGGTNCETP-----------RATCLDQ------------------------- 699
EC C G+ G CE ATCLDQ
Sbjct: 436 FECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECA 495
Query: 700 ---CSGHGTFLPDTG--LCSCDPSWTGHDCSIEI--CAA-DCGGHGVCVGG----TCRCE 747
C +G L C C +TGH C ++ CA+ C C+ G TC C
Sbjct: 496 SSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCT 555
Query: 748 DGWMGAAC--DQRACHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCP 801
+G+ G C D C P +G+C+DG C C PG+ G HC + + E
Sbjct: 556 EGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC------ETNINECSS 609
Query: 802 GLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP 861
C G C N + C C G G C+ +++ C S + G L +C +P
Sbjct: 610 QPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD-CASSPCDSGTCLDKIDGYECACEP 668
Query: 862 -----LCHIN-PLCLGSP 873
+C+IN C G+P
Sbjct: 669 GYTGSMCNINIDECAGNP 686
Score = 81.6 bits (200), Expect = 1e-14
Identities = 87/328 (26%), Positives = 111/328 (33%), Gaps = 88/328 (26%)
Query: 561 ESVDNCPSN-CYGNGDCI----SGTCHCFLGFLG-------PDCGRASCPVL----CSGN 604
E +D C S+ C G C+ + C C G G DC PV C N
Sbjct: 1182 EEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNN 1241
Query: 605 G----QYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGT--CITGT----CICNPGYKG 654
G Q C C G+ G C+ N+C+ C GT C+ C C G+ G
Sbjct: 1242 GTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTG 1301
Query: 655 ESCEEV--DCMDPTCSGRGVC------VRG-ECHCSVGWGGTNCETPRATCLD-QCSGHG 704
CE V C C G C RG C C G+ G CE TC +C G
Sbjct: 1302 RRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGG 1361
Query: 705 TFL--PDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHP 762
T + P + C C +TG +C + C+GG
Sbjct: 1362 TCISGPRSPTCLCLGPFTGPECQFPASSP-------CLGGN------------------- 1395
Query: 763 RCAEHGTCRDG------KCECSPGWNGEHCTIAHYL----------DRVVKEGCP-GLCN 805
C GTC +C C +NG C I Y +++E C C
Sbjct: 1396 PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
Query: 806 ---GNGRCTLDLNGWHCVCQLGWRGAGC 830
GN C+L N C GW G C
Sbjct: 1456 EDAGNKVCSLQCNNHAC----GWDGGDC 1479
Score = 58.5 bits (140), Expect = 9e-08
Identities = 64/285 (22%), Positives = 99/285 (34%), Gaps = 61/285 (21%)
Query: 567 PSNCYGNGDCISGT----CHCFLGFLGPDC-------------GRASCPVLCSGNGQYMK 609
P + G +C+ C C G G C +C V + ++
Sbjct: 1275 PCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFI- 1333
Query: 610 GRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE---EVDC 662
C C +G++GA C+ C + C N GTCI+G TC+C + G C+ C
Sbjct: 1334 --CKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPC 1391
Query: 663 MDPT-CSGRGVCVRG------ECHCSVGWGGTNCETPRATCLDQCSGHGT---FLPDTGL 712
+ C +G C C C + G C LD G G P
Sbjct: 1392 LGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCH-----ILDYSFGGGAGRDIPPPLIE 1446
Query: 713 CSCDPSWTGHDCSIEICAADCGGHGV-CVGGTC--RCEDGWMGAA-------------CD 756
+C+ D ++C+ C H GG C D W CD
Sbjct: 1447 EACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCD 1506
Query: 757 QRACHPRCAEHG-TCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC 800
+ C G C+ + +C+P ++ ++C H+ D +GC
Sbjct: 1507 SQCNSAGCLFDGFDCQRAEGQCNPLYD-QYCK-DHFSDGHCDQGC 1549
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 135 bits (341), Expect = 4e-31
Identities = 108/343 (31%), Positives = 135/343 (39%), Gaps = 80/343 (23%)
Query: 563 VDNCPSNCYGNGDCIS-GTCHCFLGFLGPDCGRAS--------CPVLCS-GNGQY---MK 609
V +C C +G CI+ TC C G+ G +C A C C NG +
Sbjct: 106 VPHCADKCV-HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPIT 164
Query: 610 GRCLCHSGWKGAECD------VPTNQCID-VACSNHGTC--ITGTCICNPGYKGESCEEV 660
G C C +G++G C+ N C C N TC +TG C C PGY G CE++
Sbjct: 165 GACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDL 224
Query: 661 DCMD----PTCSGR------GVC--VRGECHCSVGWGGTNCETP------RATCLDQCSG 702
C P C R GVC V GEC C GW GT C P C +C
Sbjct: 225 -CPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQC 283
Query: 703 H--GTFLPDTGLCSCDPSWTGHDCSIE--------ICAADC----GGHGVCVGGTCRCED 748
H GT TG C C P +TG C E +CA C GG V G C CE
Sbjct: 284 HNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEA 343
Query: 749 GWMGAACDQRACHP-----RCAEHGTCR----------DGKCECSPGWNG----EHCTIA 789
G+ G C+ R C +C + C G+C C PGW+G E C+
Sbjct: 344 GFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPG 403
Query: 790 HYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDT 832
Y E C +C+ D C C G++G C T
Sbjct: 404 FY-----GEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST 441
Score = 132 bits (331), Expect = 6e-30
Identities = 108/382 (28%), Positives = 147/382 (38%), Gaps = 84/382 (21%)
Query: 565 NCPSNCYGNGDCI----SGTCHCFLGFLGPDCG------------RASCPVLCSGNGQYM 608
NC S C D + G+C C G+ G DC +C L G +
Sbjct: 451 NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTL 510
Query: 609 KGRCLCHSGWKGAECDVPTNQ------CIDVA-CSNHGTC--ITGTCICNPGYKGESCEE 659
G C C GW+G +C++P C + CS+ C TG C C PG+ G C+
Sbjct: 511 DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS 570
Query: 660 VDCMD----PTCSGRGVCVRGE--------CHCSVGWGGTNCE---TP-------RATCL 697
V C + P CS C G C C+ G+ GT C+ +P TC
Sbjct: 571 V-CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCP 629
Query: 698 DQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAAD-----------CGGHGVC--VGGTC 744
G TGLC C P +TG C+ E+C + C +G C + +C
Sbjct: 630 QCVHSSGPCHHITGLCDCLPGFTGALCN-EVCPSGRFGKNCAGICTCTNNGTCNPIDRSC 688
Query: 745 RCEDGWMGAACDQRA--CH--PRCAEHGTCR--------DGKCECSPGWNGEHCTIAHYL 792
+C GW+G+ C Q H P C C DG+C+C+PGW G +CT L
Sbjct: 689 QCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPL 748
Query: 793 DRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG-DGLVD 851
K+ C +C D C C+ G+ G C E C G + D
Sbjct: 749 GFYGKD-CALICQCQNGADCDHISGQCTCRTGFMGRHC----EQKCPSGTYGYGCRQICD 803
Query: 852 CMDPDCCLQPLCHINPLCLGSP 873
C++ C HI C SP
Sbjct: 804 CLNNSTC----DHITGTCYCSP 821
Score = 123 bits (309), Expect = 2e-27
Identities = 99/346 (28%), Positives = 124/346 (35%), Gaps = 90/346 (26%)
Query: 565 NCPSNCY----GNGDCISGTCHCFLGFLGPDCGRASCPV-----LCS--------GNGQY 607
NC C G D +G CHC G+ G C + CPV LC+ G +
Sbjct: 276 NCSQECQCHNGGTCDAATGQCHCSPGYTGERC-QDECPVGTYGVLCAETCQCVNGGKCYH 334
Query: 608 MKGRCLCHSGWKGAECDVPT--NQCIDVACSNHGTC----------ITGTCICNPGYKGE 655
+ G CLC +G+ G C+ + C C ++G C C PG+ G
Sbjct: 335 VSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGL 394
Query: 656 SCEEV--------DCMDP-TCSGRGVC--VRGECHCSVGWGGTNCETP------RATCLD 698
C E C +C C V G+C C+ G+ G +C TP C
Sbjct: 395 YCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSS 454
Query: 699 Q--CSGHGTFLPDTGLCSCDPSWTGHDCSIEI--------CAADC----GGHGVCVGGTC 744
+ C P G C+C W G DCSI C C GG + GTC
Sbjct: 455 RCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTC 514
Query: 745 RCEDGWMGAACDQRACHP-----RCAEHGTC--------RDGKCECSPGWNGEHCTIAHY 791
C GW G C + C CAE C G C C PGW+G HC
Sbjct: 515 TCAPGWRGEKC-ELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHC----- 568
Query: 792 LDRVVKEG-------CPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
D V EG P C C+ D C C G+RG C
Sbjct: 569 -DSVCAEGRWGPNCSLPCYCKNGASCSPD--DGICECAPGFRGTTC 611
Score = 108 bits (271), Expect = 6e-23
Identities = 86/280 (30%), Positives = 110/280 (39%), Gaps = 70/280 (25%)
Query: 609 KGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEV---DCMD 664
K +C C ++ E VP C D HG CI TC C PG+ G +C D
Sbjct: 91 KSQC-CPGFYESGEMCVP--HCADKCV--HGRCIAPNTCQCEPGWGGTNCSSACDGDHWG 145
Query: 665 PTCSGRGVC--------VRGECHCSVGWGGTNCE------TPRATCLD--QCSGHGTFLP 708
P C+ R C + G CHC+ G+ G CE T C QC T
Sbjct: 146 PHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDH 205
Query: 709 DTGLCSCDPSWTGHDCSIEICA-----------ADCGGHGVC--VGGTCRCEDGWMGAAC 755
TG C C P +TG C ++C C GVC V G C C GWMG C
Sbjct: 206 VTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVC 264
Query: 756 DQ--------RACHPRCAEH--GTC--RDGKCECSPGWNGEHCTIAHYLDRVVKEGCPG- 802
Q + C C H GTC G+C CSPG+ GE C ++ CP
Sbjct: 265 GQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC----------QDECPVG 314
Query: 803 ----LCNGNGRCTLDLNGWH----CVCQLGWRGAGCDTSM 834
LC +C +H C+C+ G+ G C+ +
Sbjct: 315 TYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL 354
Score = 88.6 bits (218), Expect = 8e-17
Identities = 77/254 (30%), Positives = 100/254 (39%), Gaps = 64/254 (25%)
Query: 565 NCPSNCY-GNGDCIS---GTCHCFLGFLGPDCGRA------------SCP--VLCSGNGQ 606
NC CY NG S G C C GF G C R +CP V SG
Sbjct: 580 NCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCH 639
Query: 607 YMKGRCLCHSGWKGAECD--VPTNQ----CIDVA-CSNHGTC--ITGTCICNPGYKGESC 657
++ G C C G+ GA C+ P+ + C + C+N+GTC I +C C PG+ G C
Sbjct: 640 HITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDC 699
Query: 658 EEV--------DCMDP-TCSGRGVCVR--GECHCSVGWGGTNCETPRA---------TCL 697
+ +C+ C C GEC C+ GW G C T R +
Sbjct: 700 SQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYC-TQRCPLGFYGKDCALI 758
Query: 698 DQCSGHGTFLPDTGLCSCDPSWTGHDCSI------------EICAADCGGHGVC--VGGT 743
QC +G C+C + G C +IC DC + C + GT
Sbjct: 759 CQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQIC--DCLNNSTCDHITGT 816
Query: 744 CRCEDGWMGAACDQ 757
C C GW GA CDQ
Sbjct: 817 CYCSPGWKGARCDQ 830
Score = 33.1 bits (74), Expect = 3.9
Identities = 49/179 (27%), Positives = 62/179 (34%), Gaps = 36/179 (20%)
Query: 696 CLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAAC 755
CL C GT P L DP+ H S + + H C D C
Sbjct: 13 CLLLCHWIGTASP---LNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKC 69
Query: 756 DQRACHPRCA-EHG--TCRDGKCECSPGW--NGEHCTIAHYLDRVVKEGCPGLCNGNGRC 810
+ R A HG T K +C PG+ +GE C + H D+ V +GRC
Sbjct: 70 TRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMC-VPHCADKCV----------HGRC 118
Query: 811 TLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLC 869
C C+ GW G C +AC DGD P C + C LC
Sbjct: 119 IAPNT---CQCEPGWGGTNC----SSAC------DGDH----WGPHCTSRCQCKNGALC 160
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 133 bits (335), Expect = 2e-30
Identities = 106/364 (29%), Positives = 139/364 (38%), Gaps = 58/364 (15%)
Query: 576 CISGTCHCFLGF---LGPDCGRASCPVLCSGNGQYMKG-----RCLCHSGWKGAECDVPT 627
C G C G GP + +C +G+ + C+C SG+ G C
Sbjct: 540 CPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENI 599
Query: 628 NQCIDVACSNHGTCITGT----CICNPGYKGESCEEV--DCMDPTCSGRGVCVR----GE 677
+ C+ C N GTCI C C G++GE C+ DC+ C RG C
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 659
Query: 678 CHCSVGWGGTNCETPRATC-LDQCSGHGTFLP--DTGLCSCDPSWTGHDCSI---EICAA 731
C C GW G C + C CS GT DT C+C P W G C++ C
Sbjct: 660 CACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLP 719
Query: 732 D-CGGHGVCVGG----TCRCEDGWMGAACDQRA--CHPR-CAEHGTCRDG----KCECSP 779
+ C G CVG +C C DGW G C C+P C G C DG +CEC+P
Sbjct: 720 NPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAP 779
Query: 780 GWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD--TSMETA 837
G+ G C I + E C C ++NG+ C C G G C +
Sbjct: 780 GFAGPDCRIN------IDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRS 833
Query: 838 C---GDSKDNDGDGLVDCMDPDC------CLQPLCHINP-LCLGSPNPLDIIQETQVPVS 887
C G + + DC C C + C P L G P L Q P+
Sbjct: 834 CWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEAL----SAQCPLG 889
Query: 888 QQNL 891
Q+ L
Sbjct: 890 QRCL 893
Score = 132 bits (333), Expect = 4e-30
Identities = 92/319 (28%), Positives = 135/319 (42%), Gaps = 51/319 (15%)
Query: 571 YGNGDCISGTCHCFLGFLGPDCGRASCPVLCS--GNGQYMKGRCLCHSGWKGAECDVPTN 628
YGN C+ G ++G +C A C C+ G + G C C GW+G CD
Sbjct: 226 YGNKACMDG-------WMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD---- 274
Query: 629 QCIDVACSNHGTCI-TGTCICNPGYKGESCEE---VDCMDPTCSGRGVCVRGE-----CH 679
+C+ HG+C+ C C + G C++ C+ G C+ E C
Sbjct: 275 ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCT 334
Query: 680 CSVGWGGTNCETPRATCL-DQCSGHGTF--LPDTGLCSCDPSWTGHDCSIEI--CAAD-C 733
C G+ G NCE C + C+ G+ +P C C W+G C+++I CA++ C
Sbjct: 335 CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 734 GGHGVCV----GGTCRCEDGWMGAAC--DQRACHPRCAEHGTCRD----GKCECSPGWNG 783
G CV G C C + W+GA C D C +C GTC+D +C C G+ G
Sbjct: 395 AAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGG 454
Query: 784 EHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKD 843
HC + E C+ G C +G+HC C G+ G C+ ++ C S
Sbjct: 455 RHCELER------DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVD-LCEPSPC 507
Query: 844 NDG------DGLVDCMDPD 856
+G +G C PD
Sbjct: 508 RNGARCYNLEGDYYCACPD 526
Score = 127 bits (319), Expect = 2e-28
Identities = 114/381 (29%), Positives = 144/381 (37%), Gaps = 81/381 (21%)
Query: 566 CPSN-CYGNGDCI---SG-TCHCFLGFLGPDCGR-----ASCPVLCSGN--GQYMKGRCL 613
C SN C G C SG CHC G+ GP C AS P G Q C+
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECI 410
Query: 614 CHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGESCE--EVDCMDPTC 667
C W GA C + N C C + GTC + G C+C G+ G CE +C C
Sbjct: 411 CPEQWVGATCQLDVNDCRG-QCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPC 469
Query: 668 SGRGVCVR----GECHCSVGWGGTNCETPRATCLDQCSGHGTF---LPDTGLCSCDPSWT 720
G+C CHC G+ G CE C +G L C+C +
Sbjct: 470 HSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFG 529
Query: 721 GHDCS-------------IEICAAD-------------CGGHGVCV---GG--TCRCEDG 749
G +CS I+ C +D CG HG CV GG +C C+ G
Sbjct: 530 GKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSG 589
Query: 750 WMGAACDQR---ACHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
+ G C + C GTC D +C C GW GE C D + P
Sbjct: 590 FTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC------DTNPNDCLPD 643
Query: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQP- 861
C+ GRC +N ++C C GW+G C S E C ++G D D C P
Sbjct: 644 PCHSRGRCYDLVNDFYCACDDGWKGKTCH-SREFQCDAYTCSNGGTCYDSGDTFRCACPP 702
Query: 862 -----LCHI--NPLCLGSPNP 875
C + N CL PNP
Sbjct: 703 GWKGSTCAVAKNSSCL--PNP 721
Score = 110 bits (276), Expect = 1e-23
Identities = 97/374 (25%), Positives = 128/374 (34%), Gaps = 107/374 (28%)
Query: 558 TAIESVDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRA--SCPVLCSGNG---QY 607
T +D C SN C G C+ C C ++G C C C G
Sbjct: 381 TCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDL 440
Query: 608 MKG-RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCE-EVD 661
+ G +C+C G+ G C++ ++C C + G C C C G+ G CE +VD
Sbjct: 441 VNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVD 500
Query: 662 CMDPT-CSGRGVCVRGE----CHCSVGWGGTNCETPRATC-------LDQC-SGHGTFLP 708
+P+ C C E C C +GG NC PR C +D C S G +P
Sbjct: 501 LCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMP 560
Query: 709 DTGL-------------------CSCDPSWTGHDC--SIEICAAD-CGGHGVCVGGT--- 743
T C CD +TG C +I+ C C G C+
Sbjct: 561 GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 620
Query: 744 -CRCEDGWMGAACDQ---------------------------------RACHPR------ 763
C C GW G CD + CH R
Sbjct: 621 RCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA 680
Query: 764 --CAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGNGRCTLDLNG 816
C+ GTC D +C C PGW G C +A C P C G C
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAK------NSSCLPNPCVNGGTCVGSGAS 734
Query: 817 WHCVCQLGWRGAGC 830
+ C+C+ GW G C
Sbjct: 735 FSCICRDGWEGRTC 748
Score = 102 bits (254), Expect = 5e-21
Identities = 83/300 (27%), Positives = 115/300 (38%), Gaps = 60/300 (20%)
Query: 611 RCLCHSGWKGAECDV---PTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEVDCMDPT 666
R C + A C+ P N H TC G C G+ G+ C+E C
Sbjct: 195 RVRCDENYYSATCNKFCRPRNDFF-----GHYTCDQYGNKACMDGWMGKECKEAVCKQGC 249
Query: 667 CSGRGVC-VRGECHCSVGWGGTNCE--TPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHD 723
G C V GEC CS GW G C+ P C+ HG+ + + C+C+ +W G
Sbjct: 250 NLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCV-----HGSCV-EPWQCNCETNWGGLL 303
Query: 724 CSIEICAADCGGHGVCV-GGT----------CRCEDGWMGAACD--QRACHPR-CAEHGT 769
C ++ CG H C GGT C C DG+ G C+ + AC CA G+
Sbjct: 304 CDKDL--NYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGS 361
Query: 770 CRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGW 825
C + +C C GW+G C + + E C G C ++G+ C+C W
Sbjct: 362 CHEVPSGFECHCPSGWSGPTCALD------IDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 826 RGAGCDTSMETACGDSKDND---------------GDGLVDC-MDPDCCLQPLCHINPLC 869
GA C + G + G G C ++ D C CH LC
Sbjct: 416 VGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLC 475
Score = 68.9 bits (167), Expect = 6e-11
Identities = 46/141 (32%), Positives = 58/141 (41%), Gaps = 24/141 (17%)
Query: 570 CYGNGDCISGTCHCFLGFLGPDCGRA---SC---PVL----CSGNGQYMKGRCLCHSGWK 619
CY +GD C C G+ G C A SC P + C G+G C+C GW+
Sbjct: 689 CYDSGDTFR--CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS--CICRDGWE 744
Query: 620 GAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCE-EVD-CMDPTCSGRGVC 673
G C TN C + C N G C+ G C C PG+ G C +D C C+ C
Sbjct: 745 GRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATC 804
Query: 674 VRG----ECHCSVGWGGTNCE 690
V C C G G C+
Sbjct: 805 VDEINGYRCSCPPGRAGPRCQ 825
Score = 58.9 bits (141), Expect = 7e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 32/162 (19%)
Query: 557 TTAIESVDNC-PSNCYGNGDCI----SGTCHCFLGFLGPDCGRAS--C-PVLCSGNGQYM 608
T A+ +C P+ C G C+ S +C C G+ G C + C P+ C G +
Sbjct: 708 TCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICV 767
Query: 609 KG----RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEV 660
G RC C G+ G +C + ++C C+ TC+ C C PG G C+EV
Sbjct: 768 DGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEV 827
Query: 661 DCMDPTCSGRGV----------------CVRGECHCSVGWGG 686
+C RG C+ G CS W G
Sbjct: 828 IGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCG 869
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 133 bits (335), Expect = 2e-30
Identities = 102/348 (29%), Positives = 129/348 (37%), Gaps = 47/348 (13%)
Query: 558 TAIESVDNC------PSNCYGNGDCI----SGTCHCFLGFLGPDCGRASCPVL---CSGN 604
T + +D C PS C G C+ S C C G+ G C L C
Sbjct: 428 TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPG 487
Query: 605 GQYMK----GRCLCHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGES 656
+ CLC G +G C+V TN+C C NH C + G CIC PG+ G
Sbjct: 488 STCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTR 547
Query: 657 CEE--VDCMDPTCSGRGVCV----RGECHCSVGWGGTNCETPRATCL-DQCSGHGTF--L 707
CEE +C C+ G C C C G+ G C+T CL D C + L
Sbjct: 548 CEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDL 607
Query: 708 PDTGLCSCDPSWTGHDCSIEICAAD-CGGHGVCVG----GTCRCEDGWMGAACDQRACHP 762
P C C +TG C + +CA + C +C C C DG G A + C
Sbjct: 608 PGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNC-- 665
Query: 763 RCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGNGRCTLDLNGWHCVC 821
HG C+ C C GW G C GC C G C +G++C C
Sbjct: 666 -TCHHGHCQRSSCVCDVGWTGPEC-------EAELGGCISAPCAHGGTCYPQPSGYNCTC 717
Query: 822 QLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLC 869
G+ G C M TAC +G C P H P C
Sbjct: 718 PTGYTGPTCSEEM-TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQC 764
Score = 127 bits (318), Expect = 2e-28
Identities = 106/376 (28%), Positives = 136/376 (36%), Gaps = 76/376 (20%)
Query: 567 PSNCYGNGDCIS-----GTCHCFLGFLGPDC-------------GRASCPVL-------- 600
P C G C+S GTC C GFLG C SC L
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
Query: 601 CSGNGQYMKGRCLCHSGWKGAECDVP-TNQCIDVACSNHGTC---ITG--TCICNPGYKG 654
S + C C G+ G C + C CS G C +G C C PG+ G
Sbjct: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
Query: 655 ESCEEVD-CMDPTCSGRGVCV----RGECHCSVGWGGTNCETPRATCLDQ-------CSG 702
E C+ D C C GVC+ + +CHC G+ G CE C S
Sbjct: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
Query: 703 HGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR-------------CEDG 749
H T + C C G C E+ A C G GGTC+ C G
Sbjct: 212 HNTL--GSFQCLCPVGQEGPRC--ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
Query: 750 WMGAACD---QRACHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
++G C+ +C GTC+DG C C W G C + +D +G P
Sbjct: 268 FIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC--SEDVDECETQG-PP 324
Query: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSME-----TACGDSKDNDGDGLVDCMDPDC 857
C G C +HCVC GW G C+ +++ T S D G C+ P
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Query: 858 CLQPLCHINPLCLGSP 873
LCH+ +CL P
Sbjct: 385 RTGLLCHLEDMCLSQP 400
Score = 122 bits (307), Expect = 4e-27
Identities = 87/315 (27%), Positives = 126/315 (40%), Gaps = 55/315 (17%)
Query: 570 CYGNGDCI---SG-TCHCFLGFLGPDCGRA-----SCPVLCSGNGQYMKGR--CLCHSGW 618
C G C SG C C G+ GP C S P L G+ G C C
Sbjct: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH 759
Query: 619 KGAECDVPTNQCIDVACSNHGTCI----TGTCICNPGYKGESCE---EVDCMDPTCSGRG 671
G +C T+ C+ C N GTC+ T +C+C G++G CE C D C R
Sbjct: 760 TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
Query: 672 VCVRG----ECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGL---CSCDPSWTGHDC 724
C C C G+ G +C+T C + + TG C C WTG C
Sbjct: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
Query: 725 SIEICAAD-------------CGGHGVCVGGT----CRCEDGWMGAACDQRA--CHPRCA 765
++ + + C G+CV C C G+ G+ C C R
Sbjct: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPC 939
Query: 766 EHG-TCRDGK----CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCV 820
++G TC C+C+PG++G++C+ LD + C + +G CT G+HC
Sbjct: 940 QNGATCMAQPSGYLCQCAPGYDGQNCS--KELDACQSQPC----HNHGTCTPKPGGFHCA 993
Query: 821 CQLGWRGAGCDTSME 835
C G+ G C+ ++
Sbjct: 994 CPPGFVGLRCEGDVD 1008
Score = 117 bits (294), Expect = 1e-25
Identities = 120/437 (27%), Positives = 160/437 (36%), Gaps = 119/437 (27%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRAS--CPVLCSGNG---QYMKGR------CLC 614
CP + S C C +G GP C + CP NG Q M + CLC
Sbjct: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 615 HSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESC-EEVDCMD----P 665
G+ G +C+V + C+ C N GTC G TC+C + G C E+VD + P
Sbjct: 265 PPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP 324
Query: 666 TCSGRGVCVRG----ECHCSVGWGGTNCE-----------TPRATCLDQCSGHGTFLPDT 710
C G C C C GWGGT+CE P +TC+D+ G+F
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRV---GSF---- 377
Query: 711 GLCSCDPSWTGHDCSIE-ICAAD-CGGHGVC-----VGGT-CRCEDGWMGAACDQRACH- 761
C C P TG C +E +C + C G C G T C C+ G+ G C Q
Sbjct: 378 -SCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 762 ------PRCAEHG-----TCRDGKCECSPGWNGEHCTIAH-------------YLDRVVK 797
P EHG T C C PG+ G C H LD +
Sbjct: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLAT 496
Query: 798 EGC---PGL----------------CNGNGRCTLDLNGWHCVCQLGWRGAGCDTSME--- 835
C PGL C + C LNG+ C+C G+ G C+ ++
Sbjct: 497 FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR 556
Query: 836 -TAC---GDSKDNDGDGLVDCM----------DPDCCLQPLCHINPLCLGSPNPLDII-- 879
+ C G +D G C+ + D CL C + CL P +
Sbjct: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
Query: 880 -----QETQVPVSQQNL 891
Q +VP+ NL
Sbjct: 617 SGFTGQLCEVPLCAPNL 633
Score = 117 bits (293), Expect = 2e-25
Identities = 104/371 (28%), Positives = 141/371 (38%), Gaps = 86/371 (23%)
Query: 562 SVDNCPSN-CYGNGDCIS--GT--CHCFLGFLGPDCG---RASCP-------VLCSGNGQ 606
S D C S C+ G C++ GT C C +GF GP C R SC C + Q
Sbjct: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
Query: 607 YMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCI-TGT---CICNPGYKGESC----- 657
RCLC +G+ G C + C C + C+ TG C+C G+ G C
Sbjct: 827 --GPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLS 884
Query: 658 --------EEVDCMDPTCSGRGVCVRGE----CHCSVGWGGTNCETPRATCLDQ-CSGHG 704
+ +D + C G+CV CHC G+ G+ C+ C + C
Sbjct: 885 SCQKAALSQGID-VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGA 943
Query: 705 TFL--PDTGLCSCDPSWTGHDCSIEICAAD---CGGHGVCV----GGTCRCEDGWMGAAC 755
T + P LC C P + G +CS E+ A C HG C G C C G++G C
Sbjct: 944 TCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRC 1003
Query: 756 D-------QRACHPR--CAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC--PGLC 804
+ + CHP A H C+C PG G+ C + +D + C G C
Sbjct: 1004 EGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVE--IDPCHSQPCFHGGTC 1061
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCH 864
L G+ C C G+ G C + +CG CH
Sbjct: 1062 EATAGSPL---GFICHCPKGFEGPTC-SHRAPSCGFHH--------------------CH 1097
Query: 865 INPLCLGSPNP 875
LCL SP P
Sbjct: 1098 HGGLCLPSPKP 1108
Score = 103 bits (258), Expect = 2e-21
Identities = 84/303 (27%), Positives = 118/303 (38%), Gaps = 68/303 (22%)
Query: 590 PDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG----T 645
P C C +G + C+C GW G EC+ CI C++ GTC
Sbjct: 656 PGCAPPEDNCTCH-HGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYN 714
Query: 646 CICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT 705
C C GY G +C E + T G C+ G C+ GG
Sbjct: 715 CTCPTGYTGPTCSE----EMTACHSGPCLNGG-SCNPSPGGY------------------ 751
Query: 706 FLPDTGLCSCDPSWTGHDC--SIEIC-AADCGGHGVCVG--GT--CRCEDGWMGAACDQR 758
C+C PS TG C S + C +A C G CV GT C C G+ G C+ +
Sbjct: 752 ------YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
Query: 759 ACHPRCAE-----HGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGR 809
P CA+ TC+D +C C G+ G C +D ++ CP N
Sbjct: 806 -LRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT--LMDLCAQKPCP----RNSH 858
Query: 810 CTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLC 869
C +HC+C GW G C+ + ++C + + G +D + LCH LC
Sbjct: 859 CLQTGPSFHCLCLQGWTGPLCNLPL-SSCQKAALSQG---ID-------VSSLCHNGGLC 907
Query: 870 LGS 872
+ S
Sbjct: 908 VDS 910
Score = 81.6 bits (200), Expect = 1e-14
Identities = 82/308 (26%), Positives = 113/308 (36%), Gaps = 56/308 (18%)
Query: 561 ESVDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRA-----SCPVLCSGNGQYMKG 610
+ V+ C S C C++ C C G+ G +C + S P G G
Sbjct: 929 DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPG 988
Query: 611 --RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT------CICNPGYKGESCE-EVD 661
C C G+ G C+ ++C+D C GT + C C PG+ G+ CE E+D
Sbjct: 989 GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEID 1048
Query: 662 -CMDPTCSGRGVCVRGE-------CHCSVGWGGTNCETPRATC-LDQCSGHGTFLPD--- 709
C C G C CHC G+ G C +C C G LP
Sbjct: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP 1108
Query: 710 --TGLCSCDPSWTGHDCSIEICAADCGGHGVCV-GGTCRCEDGWMG----AACDQRACHP 762
C+C + G DC CG C+ G+C G G +C + P
Sbjct: 1109 GFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP 1168
Query: 763 RCAE------HGTCRDGKCE--CS-PG--WNGEHCTIAHYLDRVVKEGCPGLCNGNGRCT 811
RC + G DG C+ CS PG W+G C++ V + G C + RC
Sbjct: 1169 RCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLG------VPDPWKG-CPSHSRCW 1221
Query: 812 LDLNGWHC 819
L C
Sbjct: 1222 LLFRDGQC 1229
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 131 bits (330), Expect = 8e-30
Identities = 109/371 (29%), Positives = 141/371 (38%), Gaps = 62/371 (16%)
Query: 561 ESVDNC--PSNCYGNGDCI----SGTCHCFLGFLGPDCGRA--SC-PVLCSGNGQYMKG- 610
+ VD C P+ C +G C S +C C G+ GP C + C P C G G
Sbjct: 809 QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV 868
Query: 611 ---RCLCHSGWKGAECDVPTNQCIDVACSNHGTCI----TGTCICNPGYKGESCEE--VD 661
C C G+ G C ++C+ C GTC + TC C PGY G CE+ D
Sbjct: 869 GSFSCSCLPGFAGPRCARDVDECLSNPCGP-GTCTDHVASFTCTCPPGYGGFHCEQDLPD 927
Query: 662 CMDPTCSGRGVCVRG----ECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTG---LCS 714
C +C G CV G C C G+ G +C+ CL + HG C+
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCT 987
Query: 715 CDPSWTGHDCS--IEICAAD-CGGHGVCV--GGTCRCEDGWMGAACDQRACHPR------ 763
C S+TG C ++ C+ C G CV G C C GW G CD R+ R
Sbjct: 988 CLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQI 1047
Query: 764 -------CAEHGTCRDGK----CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTL 812
C G C D C C G G HC ++ V C G C
Sbjct: 1048 GVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHC------EQEVDPCLAQPCQHGGTCRG 1101
Query: 813 DLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVD------CMDPDCCLQPLCHIN 866
+ G+ C C G+ G C+ ++ C G +D C P L LC IN
Sbjct: 1102 YMGGYMCECLPGYNGDNCEDDVD-ECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEIN 1160
Query: 867 PLCLGSPNPLD 877
G PLD
Sbjct: 1161 EDDCGPGPPLD 1171
Score = 128 bits (321), Expect = 9e-29
Identities = 107/362 (29%), Positives = 146/362 (40%), Gaps = 66/362 (18%)
Query: 564 DNCPSN-CYGNGDC----ISGT--CHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCL--- 613
D C SN C+ + C ++G C C GF G C + N GRC+
Sbjct: 353 DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ 412
Query: 614 ------CHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE-EVD- 661
C G+ G C+ N+C+ C N TC+ TCIC G+ G CE ++D
Sbjct: 413 GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE 472
Query: 662 CMDPTCSGRGVC---VRG-ECHCSVGWGGTNCE--------TP---RATCLDQCSGHGTF 706
C C GVC V G C C G+ G+ C+ TP A C+DQ
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQ------- 525
Query: 707 LPDTGLCSCDPSWTGHDC--SIEICAADCGGHGVCVGG----TCRCEDGWMGAACDQRAC 760
PD C C + G C +++ C+ D HG CV G +C C G+ G C+ +
Sbjct: 526 -PDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVD 584
Query: 761 HPR---CAEHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLD 813
R C G C D C C G G +C + +D C G C
Sbjct: 585 ECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEV--NIDDCASNPCT-----FGVCRDG 637
Query: 814 LNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLCLGSP 873
+N + CVCQ G+ G C+ + C S +G VD + CL P + PLCL
Sbjct: 638 INRYDCVCQPGFTGPLCNVEI-NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS 696
Query: 874 NP 875
+P
Sbjct: 697 HP 698
Score = 127 bits (320), Expect = 1e-28
Identities = 97/344 (28%), Positives = 135/344 (39%), Gaps = 69/344 (20%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPV-LCSGNGQYMKGRCLCHSGWKGAECD 624
CP G + CH GP GR C + +G ++ C C G++G +C
Sbjct: 67 CPPGWVGERCQLEDPCHS-----GPCAGRGVCQSSVVAGTARFS---CRCPRGFRGPDCS 118
Query: 625 VPTNQCIDVACSNHGTCITGT-----CICNPGYKGESCE-EVD-C-MDPTCSGRGVCVRG 676
+P + C+ C++ C G C C PGY+G SC +VD C + C G C+
Sbjct: 119 LP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT 177
Query: 677 ----ECHCSVGWGGTNCETPRATCLDQ-CSGHGTFLPDTGL---CSCDPSWTGHDCSIEI 728
C C G+ G CE P C C GT L C+C P + G +C + +
Sbjct: 178 PGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV 237
Query: 729 CAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDG----KCECSPGWNGE 784
DC GH RC GTC DG C+C P W G+
Sbjct: 238 --DDCPGH--------------------------RCLNGGTCVDGVNTYNCQCPPEWTGQ 269
Query: 785 HCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDN 844
CT +D + P C+ G C L G CVC GW G C +++ C +
Sbjct: 270 FCT--EDVDECQLQ--PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDD-CATAVCF 324
Query: 845 DGDGLVDCMDPDCCLQP------LCHINPLCLGSPNPLDIIQET 882
G D + C P LCH++ C+ +P D I +T
Sbjct: 325 HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDT 368
Score = 119 bits (299), Expect = 3e-26
Identities = 98/344 (28%), Positives = 125/344 (36%), Gaps = 65/344 (18%)
Query: 557 TTAIESVDNCPSNCYGNGDCISG----TCHCFLGFLGPDCGRA-----SCPVLCSGNGQY 607
T +VD+C + +G C+ G +C C G+ G C S P C G+
Sbjct: 540 TLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKC 597
Query: 608 M----KGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESC-- 657
+ K C C SG G C+V + C C+ G C G C+C PG+ G C
Sbjct: 598 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCT-FGVCRDGINRYDCVCQPGFTGPLCNV 656
Query: 658 EEVDCMDPTCSGRGVCVRGE----CHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTG-- 711
E +C C G CV GE C C G C P C + HG G
Sbjct: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGF 716
Query: 712 LCSCDPSWTGHDCSIEICAADCGGHGVCVGGT---------CRCEDGWMGAACDQRA-CH 761
C C+P W+G CS + C GGT C C G G C+ + C
Sbjct: 717 RCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCT 776
Query: 762 PRCAEH-GTCRDGK-----CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLN 815
P EH G C C C GW G C V + P C +G CT
Sbjct: 777 PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-----QDVDECAGPAPCGPHGICTNLAG 831
Query: 816 GWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCL 859
+ C C G+ G CD + DC DP+ CL
Sbjct: 832 SFSCTCHGGYTGPSCDQDIN---------------DC-DPNPCL 859
Score = 116 bits (291), Expect = 3e-25
Identities = 100/331 (30%), Positives = 132/331 (39%), Gaps = 76/331 (22%)
Query: 564 DNCPSN-CYGNGDC----ISGT----CHCFLGFLGPDCG------------RASCPVLCS 602
D C S C G G C ++GT C C GF GPDC A C V
Sbjct: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSV--G 137
Query: 603 GNGQYMKGRCLCHSGWKGAECDVPTNQC-IDVACSNHGTCI----TGTCICNPGYKGESC 657
+G+++ C C G++G C ++C + C + GTC+ + C C GY G C
Sbjct: 138 PDGRFL---CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Query: 658 EE--VDCMDPTCSGRGVCVRG-----ECHCSVGWGGTNCETPRATCLDQCSGH-----GT 705
E V C C G C + +C C G+ G NCE +D C GH GT
Sbjct: 195 ENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN----VDDCPGHRCLNGGT 250
Query: 706 FLP--DTGLCSCDPSWTGHDCSIEICAAD-----CGGHGVCV----GGTCRCEDGWMGAA 754
+ +T C C P WTG C+ ++ C G C G +C C +GW G +
Sbjct: 251 CVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES 310
Query: 755 CDQRA--CHPRCAEHG-TCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGC--PGLCN 805
C Q C HG TC D C C G G C H D V C +C+
Sbjct: 311 CSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC---HLDDACVSNPCHEDAICD 367
Query: 806 GNGRCTLDLNGWH-CVCQLGWRGAGCDTSME 835
N +NG C C G+ G CD ++
Sbjct: 368 TN-----PVNGRAICTCPPGFTGGACDQDVD 393
Score = 94.7 bits (234), Expect = 1e-18
Identities = 93/333 (27%), Positives = 120/333 (36%), Gaps = 74/333 (22%)
Query: 563 VDNCPSN-CYGNGDCISGTCHCFL--GFLGPDCGRASCPV-------------LCSGNGQ 606
VD C C G C+ +C G+ G C S P LC GQ
Sbjct: 1001 VDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQ 1060
Query: 607 YM----KGRCLCHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGESCE 658
+ C+C G G+ C+ + C+ C + GTC + G C C PGY G++CE
Sbjct: 1061 CVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
Query: 659 E--VDCMDPTCSGRGVCV----RGECHCSVGWGGTNCETPRATC-----LD---QCSGHG 704
+ +C C G C+ R C C G G CE C LD +C +G
Sbjct: 1121 DDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNG 1180
Query: 705 TFLPDTG--LCSCDPSWTGHDCSIEI---------------CAADCGGHGVCVGGTCRCE 747
T + G C+C P +TG C +I C D GG G C C
Sbjct: 1181 TCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGG-----GFRCLCH 1235
Query: 748 DGWMGAACDQ--RACHPRCAEHGTCRDGKCECSPGWNGE-----HCTIAHYLDRV--VKE 798
G+ G C C + +HG G+C SPG G HC + R V
Sbjct: 1236 AGFSGPRCQTVLSPCESQPCQHG----GQCRPSPGPGGGLTFTCHCAQPFWGPRCERVAR 1291
Query: 799 GCPGL-CNGNGRCTLDLNGWHCVCQLGWRGAGC 830
C L C C G C C G G C
Sbjct: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1324
Score = 77.0 bits (188), Expect = 2e-13
Identities = 82/332 (24%), Positives = 108/332 (32%), Gaps = 58/332 (17%)
Query: 570 CYGNGDCISGT----CHCFLGFLG-------PDCGRASCPVLCSGNGQYMKG---RCLCH 615
C NG C+ C C G+ G +C +C + + G RCLCH
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
Query: 616 SGWKGAECDVPTNQCIDVACSNHGTC---------ITGTCICNPGYKGESCEEV--DCMD 664
+G+ G C + C C + G C +T TC C + G CE V C +
Sbjct: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295
Query: 665 PTCSGRGVC---VRG-ECHCSVGWGGTNCET-------------PRATCLDQCSGHGTFL 707
C C RG C C G G +C + A CL S L
Sbjct: 1296 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL 1355
Query: 708 PDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEH 767
C+C WTG C A + C C+ + G CD+ P C
Sbjct: 1356 APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDRECNSPGCGWD 1413
Query: 768 GTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRG 827
G G C S G C C C+ + C D + C G R
Sbjct: 1414 G----GDCSLSVGDPWRQCEALQCWRLFNNSRCDPACS-SPACLYD----NFDCHAGGRE 1464
Query: 828 AGCDTSMETACGDSKDNDGDGLVD--CMDPDC 857
C+ E C D+ DG D C +C
Sbjct: 1465 RTCNPVYEKYCA---DHFADGRCDQGCNTEEC 1493
Score = 42.4 bits (98), Expect = 0.006
Identities = 37/138 (26%), Positives = 49/138 (35%), Gaps = 36/138 (26%)
Query: 764 CAEHGTC-----RDGKCECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGNGRCTLDLNG- 816
CA G C R+ C C PGW GE C + ++ C G C G G C +
Sbjct: 49 CANGGRCTQLPSREAACLCPPGWVGERCQL--------EDPCHSGPCAGRGVCQSSVVAG 100
Query: 817 ---WHCVCQLGWRGAGC---DTSMETACGD----SKDNDGDGLVDCMD-----------P 855
+ C C G+RG C D + + C S DG L C
Sbjct: 101 TARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
Query: 856 DCCLQPLCHINPLCLGSP 873
+C + C CL +P
Sbjct: 161 ECRVGEPCRHGGTCLNTP 178
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 131 bits (330), Expect = 8e-30
Identities = 107/389 (27%), Positives = 142/389 (36%), Gaps = 108/389 (27%)
Query: 570 CYGNGDCISGT-----CHCFLGFLGP-------DCGRASCPVLCSGNGQYMKGRCLCHSG 617
C N C++ C C F G DC SC RC+C G
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
Query: 618 WKGAECDVPTNQCIDVACSNHGTCITGT-------------------------------- 645
+ G+ C++ N+C C N+GTC+ T
Sbjct: 920 FSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEE 979
Query: 646 ----------CICNPGYKGESCEEV--DCMDPTCSGRGVCVRG----ECHCSVGWGGTNC 689
C+C PGY G +CE +C+ C GVC+ G C C G+ GT+C
Sbjct: 980 NCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHC 1039
Query: 690 ETPRATCLDQCSGHG--TFLPDTGLCSCDPSWTGHDCSIEI---CAADCGGHGVCV---- 740
ET CL HG T L + CSCD T C I+I + C G C
Sbjct: 1040 ETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH 1099
Query: 741 GGTCRCEDGWMGAACDQ---RACHPR-----CAEHGTCRDGK-----CECSPGWNGEHCT 787
G TC C G+ GA C++ P C G C DG C C PG++G+ C
Sbjct: 1100 GFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCE 1159
Query: 788 IAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGD 847
I + E C C +NG+ C CQ GW G C+ +E
Sbjct: 1160 IN------INECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE------------ 1201
Query: 848 GLVDCMDPDCCLQPLCHIN---PLCLGSP 873
C+ P+ C+ LC N CL +P
Sbjct: 1202 ----CI-PNSCVHELCMENEPGSTCLCTP 1225
Score = 116 bits (290), Expect = 4e-25
Identities = 95/317 (29%), Positives = 131/317 (41%), Gaps = 50/317 (15%)
Query: 561 ESVDNCPSN-CYGNGDC----ISGTCHCFLGFLGPDCGRAS--CPVL-CSGNGQ----YM 608
+ +D+C N C N C +S C C + G C + S C + C N Y
Sbjct: 732 QDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYK 791
Query: 609 KGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT------CICNPGYKGESCEE--- 659
RC C SGW G C N+C C N G C T C+C P Y G+ C +
Sbjct: 792 SYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYN 851
Query: 660 -VDCMDPTCSGRGVCV-----RGECHCSVGWGGTNCETPRATCLD-QCSGHGTF--LPDT 710
D + C C+ C C + G NCE CL C +G + +
Sbjct: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNN 911
Query: 711 GLCSCDPSWTGHDCSIEI--CAAD-CGGHGVCVGGT----CRCEDGWMGAAC--DQRACH 761
C C P ++G C IEI C+++ C +G CV T C CE + G C D C
Sbjct: 912 FRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCK 971
Query: 762 -PRCAEHGTC---RDG-KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNG 816
C + C DG C C+PG+ G +C I LD + E C +G C +N
Sbjct: 972 ISPCLDEENCVYRTDGYNCLCAPGYTGINCEI--NLDECLSEP----CLHDGVCIDGINH 1025
Query: 817 WHCVCQLGWRGAGCDTS 833
+ C C+ G+ G C+T+
Sbjct: 1026 YTCDCKSGFFGTHCETN 1042
Score = 112 bits (279), Expect = 7e-24
Identities = 90/331 (27%), Positives = 131/331 (39%), Gaps = 65/331 (19%)
Query: 591 DCGRASCPVLCSGNGQYMKGRCL--CHSGWKGAECDVPTNQCIDVACSNHGTCITG---- 644
DC ASC +++G C G+KG +C++ ++C C N TCI
Sbjct: 646 DCKSASCKN--GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNY 703
Query: 645 --------------TCICNPGYKGESCEE--VDCMDPTCSGRGVC----VRGECHCSVGW 684
+C+CNPGY G CE+ DC+ C C + +C C W
Sbjct: 704 FCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDW 763
Query: 685 GGTNCETPRATC-LDQCSGHGTF--LPDTGLCSCDPSWTGHDCSIEI--CAAD-CGGHGV 738
G CE C ++ C + T L + C C WTG +CS EI C +D C G+
Sbjct: 764 EGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGL 823
Query: 739 CVGGT------CRCEDGWMGAACDQR-----ACHPRCAEHGTC-----RDGKCECSPGWN 782
C T C C + G C QR H C + TC + C C +
Sbjct: 824 CHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883
Query: 783 GEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSK 842
G++C I VK+ C G C +N + C+C+ G+ G+ C+ + +
Sbjct: 884 GKNCEID------VKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPC 937
Query: 843 DNDGDGLVDCMDPD----CCLQPLCHINPLC 869
N+G C+D C +P H P C
Sbjct: 938 KNNG----TCVDLTNRFFCNCEPEYH-GPFC 963
Score = 103 bits (258), Expect = 2e-21
Identities = 73/290 (25%), Positives = 113/290 (38%), Gaps = 48/290 (16%)
Query: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTC----ITGTCICNPGYKGESCEEV--DCMDP 665
CLC+ G+ G C+ + CI AC ++ TC ++ C+C ++G CE+ +C
Sbjct: 719 CLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMN 778
Query: 666 TCSGRGVCV----RGECHCSVGWGGTNC-----ETPRATCLDQCSGHGTFLPDTGLCSCD 716
C C C C+ GW G NC E C++ H + +P +C C
Sbjct: 779 PCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCP 838
Query: 717 PSWTGHDCSIEICAAD-----CGGHGVCV-----GGTCRCEDGWMGAAC--DQRAC-HPR 763
P +TG C D C + C+ C C + + G C D + C
Sbjct: 839 PLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLS 898
Query: 764 CAEHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 819
C ++G C D +C C PG++G C I + E C NG C N + C
Sbjct: 899 CQDYGDCEDMVNNFRCICRPGFSGSLCEIE------INECSSEPCKNNGTCVDLTNRFFC 952
Query: 820 VCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCCLQPLCHINPLC 869
C+ + G C+ + + C+D + C+ N LC
Sbjct: 953 NCEPEYHGPFCELDVNKC----------KISPCLDEENCVYRTDGYNCLC 992
Score = 58.9 bits (141), Expect = 7e-08
Identities = 59/272 (21%), Positives = 94/272 (34%), Gaps = 53/272 (19%)
Query: 635 CSNHGTCI------TGTCICNPGYKGESCEEVD-CMDPTCSGRGVCVRG---------EC 678
CS HG C+ T +C C P + G+ C+E+D C C G C+ EC
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 679 HCSVGWGGTNCETPRATCLDQCSGHG---TFLPDTGLCSCDPSWTGHDCSIEICAADCGG 735
C + G NC C HG ++ +C CD ++G C E+ A C
Sbjct: 243 VCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFC--EVSAKPCVS 300
Query: 736 -----HGVCVGG----TCRCEDG--WMGAACDQRACHPRCAEHGT-----CRDGKCECSP 779
G+C T C G D ++GT D C CSP
Sbjct: 301 LLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSP 360
Query: 780 GWNGEHCTIAHYLDRVVKEGCPGL-CNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETAC 838
+ C + ++ C N C + C C G+ C+ +++
Sbjct: 361 IFTDLLC-------KSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCK 413
Query: 839 GDSKDNDGDGLVDCMDPDCCLQPLCHINPLCL 870
S ++C++ + C + +C+
Sbjct: 414 LLS--------INCLNEEWCFNIIGRFKYVCI 437
Score = 55.1 bits (131), Expect = 1e-06
Identities = 47/168 (27%), Positives = 68/168 (40%), Gaps = 34/168 (20%)
Query: 563 VDNCPS-NCYGNGDCISG----TCHCFLGFLGPDCGRA--SCP------VLCSGNGQYMK 609
+++C S C G C TC C G+ G C ++ +C V+C G +
Sbjct: 1080 INDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVD 1139
Query: 610 GR-----CLCHSGWKGAECDVPTNQCIDVACSNHGTC---ITG-TCICNPGYKGESCE-E 659
G C C G+ G C++ N+C C + C I G C C PG+ G CE E
Sbjct: 1140 GPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENE 1199
Query: 660 VDCMDPTC----------SGRGVCVRGECHCSVGWGGTNCETPRATCL 697
++C+ +C +C G CS+G E R TCL
Sbjct: 1200 LECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGL-LCGDEIRRITCL 1246
Score = 43.9 bits (102), Expect = 0.002
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 10/66 (15%)
Query: 635 CSNHGTC-ITGT---CICNPGYKGESCEE-VDCMDPTCSGRGVCVRGE-----CHCSVGW 684
C N G C + GT C C P + G +C + V C++ C + +C+ + C C++GW
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGW 2943
Query: 685 GGTNCE 690
G CE
Sbjct: 2944 VGRYCE 2949
Score = 43.1 bits (100), Expect = 0.004
Identities = 28/127 (22%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 724 CSIEICAADCGGHGVCVGG------TCRCEDGWMGAACDQ-RACHPR-CAEHGTCRDGK- 774
C + + C GHG C+ +C C+ + G C + AC + C +G+C + +
Sbjct: 174 CQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRE 233
Query: 775 --------CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWR 826
C C P + G++C+ ++ + P +C + N + C C +
Sbjct: 234 NWDEQAYECVCHPPFTGKNCS------EIIGQCQPHVCFHGNCSNITSNSFICECDEQFS 287
Query: 827 GAGCDTS 833
G C+ S
Sbjct: 288 GPFCEVS 294
Score = 40.0 bits (92), Expect = 0.032
Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 7/88 (7%)
Query: 763 RCAEHGTCRDGK----CECSPGWNGEHCT-IAHYLDRVVKEGCPGLCNGNGRCTLDLNGW 817
+C GTC + C C+ GW G CT D + P C+ C +G+
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCD--PEHDPPHHCSRGATCISLPHGY 2675
Query: 818 HCVCQLGWRGAGCDTSMETACGDSKDND 845
C C LG G C+ ++ + + N+
Sbjct: 2676 TCFCPLGTTGIYCEQALSISDPSFRSNE 2703
Score = 39.3 bits (90), Expect = 0.055
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 11/76 (14%)
Query: 623 CDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCEEVDCMDPTCSGRGVCVRGE- 677
C VP C C N+GTCI+ C C Y G+ C+ C + C CV
Sbjct: 2334 CHVPW--CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSG 2391
Query: 678 ----CHCSVGWGGTNC 689
C C G G C
Sbjct: 2392 TDIVCLCPYGRSGPLC 2407
Score = 38.9 bits (89), Expect = 0.071
Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 27/97 (27%)
Query: 755 CDQRACHPRCAEHGTCRDG----------KCECSPGWNGEHCTIAHYLDRVVKEGC-PGL 803
CD AC + TCR+G C C P W G C + C L
Sbjct: 2874 CDGTACG-----YNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQS--------VSCLNNL 2920
Query: 804 CNGNGRCTLDLN-GWHCVCQLGWRGAGCD--TSMETA 837
C C D + + C+C LGW G C+ TS TA
Sbjct: 2921 CLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTA 2957
Score = 38.1 bits (87), Expect = 0.12
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 23/94 (24%)
Query: 592 CGRASCPVLCSGNGQYMKGRCL---------CHSGWKGAECDVPTNQCIDV-----ACSN 637
C + C ++ GNG G C+ C +GWKG+ C + C CS
Sbjct: 2609 CHASPCSLMKCGNG----GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSR 2664
Query: 638 HGTCIT----GTCICNPGYKGESCEE-VDCMDPT 666
TCI+ TC C G G CE+ + DP+
Sbjct: 2665 GATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 37.4 bits (85), Expect = 0.21
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 12/96 (12%)
Query: 649 NPGYKGESCEEVDCMDPTCSGRGVCVRGE----CHCSVGWGGTNCETPRATCLDQ----- 699
N G C C C G C+ C+C+ GW G+ C +TC +
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 700 -CSGHGT--FLPDTGLCSCDPSWTGHDCSIEICAAD 732
CS T LP C C TG C + +D
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISD 2696
Score = 37.0 bits (84), Expect = 0.27
Identities = 25/85 (29%), Positives = 29/85 (34%), Gaps = 11/85 (12%)
Query: 651 GYKGES----CEEVDCMDPTCSGRGVC-VRG---ECHCSVGWGGTNCETPRATCLDQCSG 702
G KG S C+ C TC G C V G C C W G C + + C
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLH 2923
Query: 703 HGTFLPDTGL---CSCDPSWTGHDC 724
+PD C C W G C
Sbjct: 2924 QSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 37.0 bits (84), Expect = 0.27
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 11/80 (13%)
Query: 686 GTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAAD--CGGHGVCV--- 740
GT C +C+ +GT T C C P W G+ C+ + + C +C+
Sbjct: 2876 GTACGYNTCRNGGECTVNGT----TFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQ 2931
Query: 741 --GGTCRCEDGWMGAACDQR 758
+C C GW+G C+ +
Sbjct: 2932 SFSYSCLCTLGWVGRYCENK 2951
Score = 36.2 bits (82), Expect = 0.46
Identities = 29/101 (28%), Positives = 35/101 (34%), Gaps = 26/101 (25%)
Query: 702 GHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCV-GGT---CRCEDGWMGAACDQ 757
GH G C P CS+ CG G C+ GT C C GW G+ C +
Sbjct: 2598 GHPNAGRSVGQCHASP------CSL----MKCGNGGTCIESGTSVYCNCTTGWKGSFCTE 2647
Query: 758 --RACHP------RCAEHGTC----RDGKCECSPGWNGEHC 786
C P C+ TC C C G G +C
Sbjct: 2648 TVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
Score = 35.4 bits (80), Expect = 0.79
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 10/77 (12%)
Query: 589 GPDCGRASCPV--LCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG-- 644
G CG +C C+ NG RCL W G C+ + C++ C + CI
Sbjct: 2876 GTACGYNTCRNGGECTVNGTTFSCRCL--PDWAGNTCNQSVS-CLNNLCLHQSLCIPDQS 2932
Query: 645 ---TCICNPGYKGESCE 658
+C+C G+ G CE
Sbjct: 2933 FSYSCLCTLGWVGRYCE 2949
Score = 35.0 bits (79), Expect = 1.0
Identities = 84/409 (20%), Positives = 123/409 (30%), Gaps = 117/409 (28%)
Query: 561 ESVDNCPSN-CYGNGDCISGT---------CHCFLGFLGPDC----GRASCPVLCSGNGQ 606
+ +D C C NG CI+ C C F G +C G+ V GN
Sbjct: 212 QELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271
Query: 607 YMKGR---CLCHSGWKGAECDVPTNQCID------------------------------- 632
+ C C + G C+V C+
Sbjct: 272 NITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGET 331
Query: 633 -------VACSNHGTCITGT----CICNPGYKGESCEEV--DCMDPTCSGRGVCVRGE-- 677
V C N CI + CIC+P + C+ + C C + E
Sbjct: 332 DVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKD 391
Query: 678 --CHCSVGWGGTNCETP-------RATCLDQ-----CSGHGTFLPDTGLCSCDPSWTGHD 723
C C G+ NCE CL++ G ++ G C+ +P W +
Sbjct: 392 YPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG-CTKNPCWFLKN 450
Query: 724 CSI---EICAADCGGHGVCVG-GTCRCEDGWM--GAACDQRACH----------PRCAEH 767
+ +C HG+C G + E W A + C C E
Sbjct: 451 VYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTED 510
Query: 768 GTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTL--DLNGWHCVCQLGW 825
T + P N C H EG +C C D + +C L W
Sbjct: 511 ATYVN-----DPEDNNSSCWFPH-------EGTKEICANGCSCLSEEDSQEYRYLCFLRW 558
Query: 826 RGAGCDTSMETACGDSKDNDGDGLVDCMD----PDCCLQPLCHINPLCL 870
G + +E D ++N+ C D P C L +I LC+
Sbjct: 559 AG---NMYLENTT-DDQENECQHEAVCKDEINRPRCSCS-LSYIGRLCV 602
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 131 bits (329), Expect = 1e-29
Identities = 100/335 (29%), Positives = 124/335 (37%), Gaps = 79/335 (23%)
Query: 569 NCYGNGDCI--SGTCHCFLGFLGPDCGRASCP---------VLCSGNGQY------MKGR 611
+C + C +G C C GF G C CP C+ + ++ M G
Sbjct: 320 DCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGE 379
Query: 612 CLCHSGWKGAECDVPTNQCID-VACSNHGTCI--------TGTCICNPGYKGESCEEV-- 660
C C GW G C+ Q C H C+ +G C C PGY G C +
Sbjct: 380 CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCP 439
Query: 661 -DCMDPTCSGRGVC--------VRGECHCSVGWGGTNCETP----------RATCLDQCS 701
D CS R C + GEC C GW NC P A+C QC+
Sbjct: 440 PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASC--QCA 497
Query: 702 GHGTFLPDTGLCSCDPSWTGHDCSI--------EICAA--DCGGHGVC--VGGTCRCEDG 749
P TG C+C P W G C + E CA+ DC C V G C+C+ G
Sbjct: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAG 557
Query: 750 WMGAACD------------QRACHPRCAEHGTC--RDGKCECSPGWNGEHCTIAHYLDRV 795
WMGA C C C GTC +G C C+PG+ G C + R
Sbjct: 558 WMGARCHLSCPEGLWGVNCSNTC--TCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRY 615
Query: 796 VKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
K P C + C NG C C GW G C
Sbjct: 616 GKRCVPCKCANHSFCH-PSNG-TCYCLAGWTGPDC 648
Score = 119 bits (298), Expect = 4e-26
Identities = 88/308 (28%), Positives = 118/308 (38%), Gaps = 61/308 (19%)
Query: 583 CFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAEC--DVPTNQ----CIDVA-C 635
C GF GP+C + C G G+C C G+ G C + P + C + C
Sbjct: 263 CPEGFHGPNCSQ-ECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC 321
Query: 636 SNHGTCI--TGTCICNPGYKGESCEEVDCMDP----TCSGRGVCVR----------GECH 679
+ C G C+C G+ G+ C + C D +C C R GEC
Sbjct: 322 APDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECS 381
Query: 680 CSVGWGGTNCET--PRATCLDQCSGH------GTFLPDTGLCSCDPSWTGHDCSIEICAA 731
C GW G +C P+ T C H G +GLC C P +TG C+ +C
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCA-SLCPP 440
Query: 732 D-----CGGHGVC--------VGGTCRCEDGWMGAACDQRACHP-----------RCAEH 767
D C C + G C C++GW C C P +CA
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV-PCPPGTWGFSCNASCQCAHE 499
Query: 768 GTC--RDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGW 825
C + G C C+PGW+G HC + + EGC C+ + D C CQ GW
Sbjct: 500 AVCSPQTGACTCTPGWHGAHCQLPCPKGQF-GEGCASRCDCDHSDGCDPVHGRCQCQAGW 558
Query: 826 RGAGCDTS 833
GA C S
Sbjct: 559 MGARCHLS 566
Score = 111 bits (278), Expect = 9e-24
Identities = 79/271 (29%), Positives = 103/271 (38%), Gaps = 70/271 (25%)
Query: 565 NCPSNCYGNGDCI----SGTCHCFLGFLGPDCGRASCPVLCSGNG-------------QY 607
+C ++C + + +G C C G+ G C + CP G G
Sbjct: 489 SCNASCQCAHEAVCSPQTGACTCTPGWHGAHC-QLPCPKGQFGEGCASRCDCDHSDGCDP 547
Query: 608 MKGRCLCHSGWKGAECDVP----------TNQCIDVACSNHGTCI--TGTCICNPGYKGE 655
+ GRC C +GW GA C + +N C C N GTC+ G C+C PG++G
Sbjct: 548 VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC---TCKNGGTCLPENGNCVCAPGFRGP 604
Query: 656 SCEEV--------DCMDPTCSGRGVC--VRGECHCSVGWGGTNCETP------RATCLDQ 699
SC+ C+ C+ C G C+C GW G +C P C
Sbjct: 605 SCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQT 664
Query: 700 CSGH--GTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQ 757
C H GT P G C C WTGH C +E C G G C+C G
Sbjct: 665 CQCHHGGTCHPQDGSCICPLGWTGHHC-LEGC--PLGTFGANCSQPCQCGPG-------- 713
Query: 758 RACHPRCAEHGTCRDGKCECSPGWNGEHCTI 788
CHP G C C PG +G C I
Sbjct: 714 EKCHP--------ETGACVCPPGHSGAPCRI 736
Score = 103 bits (257), Expect = 2e-21
Identities = 95/327 (29%), Positives = 110/327 (33%), Gaps = 86/327 (26%)
Query: 566 CPSNCYGNGDCIS-GTCHCFLGFLGPDCGRASCPVL----------CSGNGQY--MKGRC 612
C C +G C++ C C G+ G DC P + C N G C
Sbjct: 105 CAQECV-HGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVC 163
Query: 613 LCHSGWKGAECDVPT-----NQCIDVACSNHGTCI---TGTCICNPGYKGESCEEVDCMD 664
C SG + C P C HG TG C C G SC +V C
Sbjct: 164 SCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSC-DVSCSQ 222
Query: 665 PT----------CSGRGV--CVRGECHCSVGWGGTNCETP------RATCLDQCSGHGTF 706
T C GV +G C C GW GT C P C +C H
Sbjct: 223 GTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGG 282
Query: 707 LPD--TGLCSCDPSWTGHDCSIEI--------CA--ADCGGHGVC--VGGTCRCEDGWMG 752
L D TG C C P +TG C E CA DC C G C CE G+ G
Sbjct: 283 LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTG 342
Query: 753 AACDQRACHP-----RCAEHGTC----------RDGKCECSPGWNGEHCTIAHYLDRVVK 797
C R C C TC +G+C C PGW G HC
Sbjct: 343 DRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHC----------N 392
Query: 798 EGCPGLCNGNGRCTLDLNGWHCVCQLG 824
E CP +G G C HC+C G
Sbjct: 393 ESCPQDTHGPG-CQ-----EHCLCLHG 413
Score = 79.3 bits (194), Expect = 5e-14
Identities = 61/209 (29%), Positives = 81/209 (38%), Gaps = 45/209 (21%)
Query: 564 DNCPSNC---YGNG-DCISGTCHCFLGFLGPDCGRASCP-----------VLCSGNGQYM 608
+ C S C + +G D + G C C G++G C SCP C G +
Sbjct: 531 EGCASRCDCDHSDGCDPVHGRCQCQAGWMGARC-HLSCPEGLWGVNCSNTCTCKNGGTCL 589
Query: 609 --KGRCLCHSGWKGAECDVPTN------QCIDVACSNHGTC--ITGTCICNPGYKGESCE 658
G C+C G++G C +C+ C+NH C GTC C G+ G C
Sbjct: 590 PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCS 649
Query: 659 EV--------DCMDPT-CSGRGVC--VRGECHCSVGWGGTNC------ETPRATCLDQCS 701
+ +C C G C G C C +GW G +C T A C C
Sbjct: 650 QPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQ 709
Query: 702 -GHGTFL-PDTGLCSCDPSWTGHDCSIEI 728
G G P+TG C C P +G C I I
Sbjct: 710 CGPGEKCHPETGACVCPPGHSGAPCRIGI 738
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 130 bits (326), Expect = 2e-29
Identities = 63/155 (40%), Positives = 80/155 (51%), Gaps = 7/155 (4%)
Query: 635 CSNHGTCITGTC--ICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETP 692
CS HG +C ICN G+ G++C E C CS RGVCV G+C C + G +C
Sbjct: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYC-PLGCSSRGVCVDGQCICDSEYSGDDCSEL 233
Query: 693 RATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMG 752
R C CS G + G C C+ +TG DC C DC G G C GTC CE+G++G
Sbjct: 234 R--CPTDCSSRGLCVD--GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVG 289
Query: 753 AACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCT 787
C QR C C+ G C +G C C G+ G C+
Sbjct: 290 EDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCS 324
Score = 111 bits (277), Expect = 1e-23
Identities = 60/168 (35%), Positives = 77/168 (45%), Gaps = 19/168 (11%)
Query: 665 PTCSGRGVCVRGECH--CSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGH 722
P CSG G C C+ GW G NC P C CS G + G C CD ++G
Sbjct: 173 PHCSGHGNFSFESCGCICNEGWFGKNCSEP--YCPLGCSSRGVCV--DGQCICDSEYSGD 228
Query: 723 DCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWN 782
DCS C DC G+CV G C CE+ + G C + C C+ G C +G C C G+
Sbjct: 229 DCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYV 288
Query: 783 GEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
GE C + C C+G G+C L CVC+ G++G C
Sbjct: 289 GEDCG---------QRQCLNACSGRGQCEEGL----CVCEEGYQGPDC 323
Score = 107 bits (267), Expect = 2e-22
Identities = 57/182 (31%), Positives = 79/182 (43%), Gaps = 17/182 (9%)
Query: 680 CSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVC 739
C+ + T + + CSGHG F ++ C C+ W G +CS C C GVC
Sbjct: 155 CNANCCQESAATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVC 214
Query: 740 VGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEG 799
V G C C+ + G C + C C+ G C DG+C C + GE C +
Sbjct: 215 VDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCR---------ELR 265
Query: 800 CPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMD----P 855
CPG C+G GRC NG C+C+ G+ G C + +GL C + P
Sbjct: 266 CPGDCSGKGRCA---NG-TCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGP 321
Query: 856 DC 857
DC
Sbjct: 322 DC 323
Score = 106 bits (265), Expect = 3e-22
Identities = 66/213 (30%), Positives = 89/213 (41%), Gaps = 11/213 (5%)
Query: 479 YGRKGLPPSHTQFDFVELLDGRRLLTQEARSLEGTPRQSRGTVPPSSHETGFIQYLD--S 536
+ +K P + + ELL +L +E L Q S TG + Y+ S
Sbjct: 120 FPKKACPCASSAQVLQELLSRIEMLEREVSVLRD---QCNANCCQESAATGQLDYIPHCS 176
Query: 537 GIWHLAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCFLGFLGPDCGRAS 596
G + +F + G F E CP C G C+ G C C + G DC
Sbjct: 177 GHGNFSFESCGCICNEGWFGKNCSEPY--CPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
Query: 597 CPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGES 656
CP CS G + G C+C + G +C CS G C GTC+C GY GE
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDC---RELRCPGDCSGKGRCANGTCLCEEGYVGED 291
Query: 657 CEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNC 689
C + C++ CSGRG C G C C G+ G +C
Sbjct: 292 CGQRQCLN-ACSGRGQCEEGLCVCEEGYQGPDC 323
Score = 90.5 bits (223), Expect = 2e-17
Identities = 39/95 (41%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
CP++C G C+ G C C + G DC CP CSG G+ G CLC G+ G +C
Sbjct: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCG- 293
Query: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV 660
QC++ ACS G C G C+C GY+G C V
Sbjct: 294 -QRQCLN-ACSGRGQCEEGLCVCEEGYQGPDCSAV 326
Score = 36.6 bits (83), Expect = 0.35
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCP 598
C + C G G C G C C G+ GPDC + P
Sbjct: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP 329
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 129 bits (323), Expect = 5e-29
Identities = 105/351 (29%), Positives = 136/351 (38%), Gaps = 86/351 (24%)
Query: 575 DCISGTC--HCFLGFLGPDCGRASCPV---------LCSGNG---QYMKGRCLCHSGWKG 620
D +SG C C GF G DCG+ CPV CS G + G+C C G G
Sbjct: 708 DSVSGECGKRCPAGFQGEDCGQ-ECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTG 766
Query: 621 AEC--DVPTNQ----CIDV--ACSNHGTCI--TGTCICNPGYKGESCEEVDCMDPTCSGR 670
+C D P + C ++ AC + C TG C+C PG+ G C++V
Sbjct: 767 EDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV---------- 816
Query: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEI-- 728
C GW G +C+T C C+ G P TG CSC P WTG C
Sbjct: 817 ---------CPAGWYGPSCQT---RC--SCANDGHCHPATGHCSCAPGWTGFSCQRACDT 862
Query: 729 ------CAADC---GGHGVC--VGGTCRCEDGWMGAACDQR--------ACHPRC-AEHG 768
C+ C GHG C + G C CE G++G C+Q+ C RC +HG
Sbjct: 863 GHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHG 922
Query: 769 TCRD---GKCECSPGWNG---EHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQ 822
D G C C GW G EH A + C CN D C+C
Sbjct: 923 AACDHVSGACTCPAGWRGTFCEHACPAGFFGL----DCRSACNCTAGAACDAVNGSCLCP 978
Query: 823 LGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCC--LQPLCHINPLCLG 871
G RG C ET + ++ C + C + CH P +G
Sbjct: 979 AGRRGPRC---AETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMG 1026
Score = 116 bits (290), Expect = 4e-25
Identities = 94/337 (27%), Positives = 125/337 (37%), Gaps = 70/337 (20%)
Query: 564 DNCPSNCY----GNGDCISGTCHCFLGFLGPDCGRASCP----VLCSGNGQYMKG----- 610
DNC +C G D +SG C C G+ G C + P C +G + G
Sbjct: 1040 DNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDP 1099
Query: 611 ---RCLCHSGWKGAECDVPTNQ-CIDVACSNHGTC--------ITGTCICNPGYKGESCE 658
RCLC +GW G +C P + AC+ +C +TG C C PG+ G CE
Sbjct: 1100 HTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCE 1159
Query: 659 EV--------DCMDPT-CSGRGVCVR---GECHCSVGWGGTNCET--------PRATCLD 698
+ DC C G G C C+ G+ G +C+ P L
Sbjct: 1160 QACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
Query: 699 QCSGHGTFLPDTGLCSCDPSWTGHDCSIEI--------CAADCG-GHGVC---VGGTCRC 746
C G+ TG C C + G DC++ C CG G G V GTC C
Sbjct: 1220 GCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLC 1279
Query: 747 EDGWMGAACDQRACHPR----------CAEHGTCR--DGKCECSPGWNGEHCTIAHYLDR 794
G G C++ R C G C +G C C GW G HC +A R
Sbjct: 1280 PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGR 1339
Query: 795 VVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD 831
C C+ + T + C C G+ G C+
Sbjct: 1340 -YGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Score = 115 bits (288), Expect = 6e-25
Identities = 106/354 (29%), Positives = 140/354 (39%), Gaps = 89/354 (25%)
Query: 564 DNCPSNCYGNGD---C--ISGTCHCFLGFLGPDC------GR--ASCPVLCS----GNGQ 606
++C C G+ C +GTC C G+ GP C GR C LC G+
Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCD 1228
Query: 607 YMKGRCLCHSGWKGAECDVPTNQ------CIDVA-CSNHGTC--ITGTCICNPGYKGESC 657
G C C +G+ G +C++ Q C V C C +TGTC+C PG G C
Sbjct: 1229 AATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288
Query: 658 EE--------VDCMDPTCSGR--GVC--VRGECHCSVGWGGTNCETP------RATCLDQ 699
E V C + TCS R G+C G C C +GW G +CE A C +
Sbjct: 1289 ERGCPQNRFGVGC-EHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE 1347
Query: 700 CSGHG--TFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQ 757
CS H T P TG C C P + G C C G HG G C C+ G A CD
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACE-HPCPP--GFHGAGCQGLCWCQHG---APCDP 1401
Query: 758 RACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVK-----EGCPGLCNGNGRCTL 812
+ G+C C G++G H+ +R + EGC C+ +G
Sbjct: 1402 IS-------------GRCLCPAGFHG------HFCERGCEPGSFGEGCHQRCDCDGGAPC 1442
Query: 813 DLNGWHCVCQLGWRGAGCD-----------TSMETACGDSKDNDG-DGLVDCMD 854
D C+C G GA C+ ++ CG D D G C+D
Sbjct: 1443 DPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVD 1496
Score = 113 bits (282), Expect = 3e-24
Identities = 107/386 (27%), Positives = 134/386 (34%), Gaps = 100/386 (25%)
Query: 564 DNCPSNCYG-----------NGDC--ISGTCHCFLGFLGPDCGRA----------SCPVL 600
D CP+ YG +G C +G C C G+ G C RA S P
Sbjct: 815 DVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCN 874
Query: 601 CS---GNGQYMKGRCLCHSGWKGAECDVPTNQ------CIDVACSNHGTC---ITGTCIC 648
CS G+ + G CLC +G+ G C+ Q C HG ++G C C
Sbjct: 875 CSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTC 934
Query: 649 NPGYKGESCEE--------VDCMDP-TCSGRGVC--VRGECHCSVGWGGTNCETPRATCL 697
G++G CE +DC C+ C V G C C G G C TC
Sbjct: 935 PAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE---TCP 991
Query: 698 DQCSGHGTFL-----------PDTGLCSCDPSWTGHDCSIEICAAD-----------CGG 735
GH P G C C P W G C ++ C A C
Sbjct: 992 AHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQN 1050
Query: 736 HGVC--VGGTCRCEDGWMGAACDQRACHPR-----CAEHGTC--------RDGKCECSPG 780
G C V G C C +GW G AC ++ C PR C G C G+C C G
Sbjct: 1051 GGTCDPVSGHCACPEGWAGLAC-EKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAG 1109
Query: 781 WNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGD 840
W G+ C + L E C C+ C C G+ G+GC E AC
Sbjct: 1110 WTGDKCQ-SPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC----EQACPP 1164
Query: 841 SKDNDGDGLVDCMDPDCC--LQPLCH 864
+ DC C P CH
Sbjct: 1165 GSFGE-----DCAQMCQCPGENPACH 1185
Score = 95.9 bits (237), Expect = 5e-19
Identities = 78/251 (31%), Positives = 99/251 (39%), Gaps = 64/251 (25%)
Query: 565 NCPSNC-YGNG---DCISGTCHCFLGFLGPDCGRA--------SCPVLCS----GNGQYM 608
NC C G G D ++GTC C G G C R C CS G
Sbjct: 1257 NCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHAS 1316
Query: 609 KGRCLCHSGWKGAECDV--PTNQC-----IDVACSNHGTC--ITGTCICNPGYKGESCEE 659
G C C GW G C++ P + ++ +C N+ TC TGTC C PG+ G++CE
Sbjct: 1317 NGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEH 1376
Query: 660 VDCMDPTCSG---RGVC----------VRGECHCSVGWGGTNCETP----------RATC 696
P G +G+C + G C C G+ G CE C
Sbjct: 1377 P--CPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRC 1434
Query: 697 LDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEI--------CA--ADCGGHGVC--VGGTC 744
C G P TGLC C P +G C+++ C DCGG C V G C
Sbjct: 1435 --DCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQC 1492
Query: 745 RCEDGWMGAAC 755
C DG+MG C
Sbjct: 1493 HCVDGYMGPTC 1503
Score = 85.5 bits (210), Expect = 7e-16
Identities = 96/338 (28%), Positives = 110/338 (32%), Gaps = 86/338 (25%)
Query: 583 CFLGFLGPDCGRASCPVLCSGNGQYMKGR--CLCHSGWKGAECDVPT-------NQCIDV 633
C G DC +C C G + G C C GW G C+ N
Sbjct: 511 CLDDSFGHDCS-LTCDD-CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSC 568
Query: 634 ACSNHGTC--ITGTCICNPGYKGESCEE--------VDCMDP-TCSGRGVCVR--GECHC 680
+C N GTC +TG C C PG G +CE+ C C+ RG C R G C C
Sbjct: 569 SCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLC 628
Query: 681 SVGWGGTNCETPRATCLDQCSGHG------TFLPDT-------GLCSCDPSWTGHDCSIE 727
G G C TC G G P T G CSC + G C E
Sbjct: 629 DPGLYGRFC---HLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAE 685
Query: 728 ------------ICAADCGGHGVCVGGTC--RCEDGWMGAACDQRA--------CHPRCA 765
C G V G C RC G+ G C Q C C+
Sbjct: 686 CELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCS 745
Query: 766 EHGT-CR--DGKCECSPGWNGEHCTIAHYLDR---VVKEGCPGLCNGNGRCTLDLNGWHC 819
G C G+C C PG GE C R +E CP C RC + C
Sbjct: 746 CGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPA-CQHAARCDPETGACLC 804
Query: 820 -----------VCQLGWRGAGCDTSMETACGDSKDNDG 846
VC GW G C T A NDG
Sbjct: 805 LPGFVGSRCQDVCPAGWYGPSCQTRCSCA------NDG 836
Score = 58.9 bits (141), Expect = 7e-08
Identities = 88/330 (26%), Positives = 120/330 (36%), Gaps = 76/330 (23%)
Query: 562 SVDNCPSNCYGNGDCISGT---CHCFLGFLGPDC---------GRASCPVLCSGN-GQYM 608
S + S C+ G C+ G+ CHC GF GP C C C G Y+
Sbjct: 125 SAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYL 184
Query: 609 KGRCLCHSGWK---GAECDVPTNQCI--DVACSNHGTCITGT---CICNPGYK----GES 656
C C G++ + + N C + C +H +T T C C PG++ G
Sbjct: 185 ---CECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRH 241
Query: 657 C-EEVDC--MDPTCSGRGVCVRG--ECHCSVGW----GGTNCE--TPRATCLDQCSGHGT 705
C C + +C R VRG C C VG+ G CE A L QC+ HG
Sbjct: 242 CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCA-HGC 300
Query: 706 FLPDTGL-CSCDPSW----TGHDC------SIEICAADCGG--HG---VCVGGTCRCEDG 749
C C + G C + C A+ GG HG G C C G
Sbjct: 301 LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRG 360
Query: 750 WMGAACDQRAC--HPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGC------- 800
+ DQR C CA+ C+ C +PG C + R+ +GC
Sbjct: 361 Y-ELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGY---RLSADGCGCEDVDE 415
Query: 801 ----PGLCNGNGRCTLDLNGWHCVCQLGWR 826
G C + CT + C C+ G+R
Sbjct: 416 CASSRGGCEHH--CTNLAGSFQCSCEAGYR 443
Score = 57.0 bits (136), Expect = 3e-07
Identities = 94/376 (25%), Positives = 119/376 (31%), Gaps = 108/376 (28%)
Query: 546 DGKESEVVSFLTTAIESVDNCPSNCYGNGDCISGTCHCF--LGFLGPDCGRASCPVLCS- 602
DGK E V + + N G+ C+ CH LG G C R ++ S
Sbjct: 279 DGKACEDVDECAAGLAQCAHGCLNTQGSFKCV---CHAGYELGADGRQCYRIEMEIVNSC 335
Query: 603 --GNGQYMKG--------RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGTCICNP-- 650
NG G C C G+ E D CIDV C C NP
Sbjct: 336 EANNGGCSHGCSHTSAGPLCTCPRGY---ELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 392
Query: 651 -------GYK----GESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCE--------- 690
GY+ G CE+V D S RG C E HC+ G C
Sbjct: 393 YECGCYAGYRLSADGCGCEDV---DECASSRGGC---EHHCTNLAGSFQCSCEAGYRLHE 446
Query: 691 -----TPRATCLDQCSGHGTFL-------------------PDTGLCSCDPSWTGHDCSI 726
+P + G F+ D G + G
Sbjct: 447 DRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLT 506
Query: 727 E--ICAADCGGH------------GVCVGGT--CRCEDGWMGAACDQRACHP-------- 762
E +C D GH G C+ G C C +GW G C++ C P
Sbjct: 507 EKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNE-TCPPDTFGKNCS 565
Query: 763 ---RCAEHGTCRD--GKCECSPGWNGEHCTIA---HYLDRVVKEGCPGLCNGNGRCTLDL 814
C GTC G C C PG +G +C Y + ++ C C GRC L
Sbjct: 566 FSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCN--CANRGRCH-RL 622
Query: 815 NGWHCVCQLGWRGAGC 830
G C+C G G C
Sbjct: 623 YG-ACLCDPGLYGRFC 637
Score = 46.6 bits (109), Expect = 3e-04
Identities = 37/128 (28%), Positives = 48/128 (37%), Gaps = 34/128 (26%)
Query: 566 CPSNCYGNG-------------DCISGTCHCFLGFLGPDCGRA--------SCPVLCSGN 604
CP +G G D ISG C C GF G C R C C +
Sbjct: 1378 CPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD 1437
Query: 605 G----QYMKGRCLCHSGWKGAECDVPTNQC-IDVACSNHGTC--------ITGTCICNPG 651
G + G CLC G GA C++ + +C+ H C ++G C C G
Sbjct: 1438 GGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDG 1497
Query: 652 YKGESCEE 659
Y G +C E
Sbjct: 1498 YMGPTCRE 1505
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 127 bits (320), Expect = 1e-28
Identities = 111/407 (27%), Positives = 144/407 (35%), Gaps = 83/407 (20%)
Query: 526 HETGFIQYLDSGIWHLAFYNDGKESEVVSFLTTAIESVDNCPSNCYGNGDC--ISGTCHC 583
H G ++ A Y + E F + + +C +C+ G C +G C C
Sbjct: 278 HHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHC--DCHNGGQCSPTTGACEC 335
Query: 584 FLGFLGPDCGRASCPVLCSGNG---------------QYMKGRCLCHSGWKGAECDVPT- 627
G+ GP C CP G G + G C C GW G C+
Sbjct: 336 EPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCP 395
Query: 628 -----NQC-IDVACSNHGTC--ITGTCICNPGYKGESCEEVDCMDPT----------CSG 669
+ C + C N C ITG C C PG+ GE C V C T C+
Sbjct: 396 VGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVC-AVSCAAGTYGPNCSSICSCNN 454
Query: 670 RGVC--VRGECHCSVGWGGTNCETP------RATCLDQ--CSGHGTFLPDTGLCSCDPSW 719
G C V G C C GW G +C P C + C+ P G CSC P W
Sbjct: 455 GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGW 514
Query: 720 TGHDCSIE----ICAADCGGHGVC--------VGGTCRCEDGWMGAACDQRACHP----- 762
G C + +C H C V G C C GW G CD C P
Sbjct: 515 LGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDS-TCPPGRWGP 573
Query: 763 ------RCAEHGTC--RDGKCECSPGWNGEHC---TIAHYLDRVVKEGCPGLCNGNGRCT 811
C G+C DG CEC+PG+ G C + + CP LC + R
Sbjct: 574 NCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP-LCVHSSRPC 632
Query: 812 LDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCMDPDCC 858
++G C C G+ GA C+ + G D L C + C
Sbjct: 633 HHISG-ICECLPGFSGALCN---QVCAGGYFGQDCAQLCSCANNGTC 675
Score = 122 bits (307), Expect = 4e-27
Identities = 99/348 (28%), Positives = 125/348 (35%), Gaps = 86/348 (24%)
Query: 566 CPSNCYG---NGDC----------ISGTCHCFLGFLGPDCGRASCP-----VLCSGNGQY 607
CPS +G N C I G+C C G+LG C CP + CS +
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCPDGTFGLNCSEHCDC 538
Query: 608 --------MKGRCLCHSGWKGAECDVPT-------NQCIDVACSNHGTCIT--GTCICNP 650
+ G C C +GW G CD N + +C N G+C G+C C P
Sbjct: 539 SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAP 598
Query: 651 GYKGESCEEVDCMDPTCSGRG------VCVR---------GECHCSVGWGGTNCETPRA- 694
G++G C+ + P G G +CV G C C G+ G C A
Sbjct: 599 GFRGPLCQRI--CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAG 656
Query: 695 -------TCLDQCSGHGTFLPDTGLCSCDPSWTGHDCS------------IEICAADCGG 735
L C+ +GT P G C C P W G DCS C+ G
Sbjct: 657 GYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA 716
Query: 736 HGVCVGGTCRCEDGWMGAACDQRA--------CHPRC-AEHGTCRD---GKCECSPGWNG 783
G C C GW G C QR C C ++G D GKC C G+ G
Sbjct: 717 SCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTG 776
Query: 784 EHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD 831
+HC GC LC T D C C G++G CD
Sbjct: 777 QHCE-QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCD 823
Score = 122 bits (305), Expect = 6e-27
Identities = 95/326 (29%), Positives = 123/326 (37%), Gaps = 78/326 (23%)
Query: 577 ISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMK-------------GRCLCHSGWKGAEC 623
I+G C C GF G C P G G + G CLC G+ G C
Sbjct: 157 ITGACVCAAGFRGWRCEELCAPGT-HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYC 215
Query: 624 D--VPTNQ----C-IDVACSNHGTC--ITGTCICNPGYKGESCEEV--------DC-MDP 665
+ P C + C N GTC ITG C C PG+ G C + +C D
Sbjct: 216 EELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC 275
Query: 666 TCSGRGVC--VRGECHCSVGWGGTNC--ETPRATCLDQCSGH------GTFLPDTGLCSC 715
C G C V G+CHC+ G+ G C E P + QCS H G P TG C C
Sbjct: 276 PCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACEC 335
Query: 716 DPSWTGHDCSIEICAADCGGHGVC---------------VGGTCRCEDGWMGAACDQR-- 758
+P + G C +C G G V G C C+ GW G C++
Sbjct: 336 EPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCP 395
Query: 759 ------ACHPRCAEHGTCRDGK--------CECSPGWNGEHCTIAHYLDRVVKEGCPGLC 804
C C TC++G C C+PG+ GE C ++ C +C
Sbjct: 396 VGYYGDGCQLPC----TCQNGADCHSITGGCTCAPGFMGEVCAVS-CAAGTYGPNCSSIC 450
Query: 805 NGNGRCTLDLNGWHCVCQLGWRGAGC 830
+ N T C C+ GW+G C
Sbjct: 451 SCNNGGTCSPVDGSCTCKEGWQGLDC 476
Score = 119 bits (297), Expect = 5e-26
Identities = 88/315 (27%), Positives = 118/315 (37%), Gaps = 69/315 (21%)
Query: 565 NCPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVL-----------CSGNGQYMK--GR 611
+CP + G D ++G CHC G++G C + CP C GQ G
Sbjct: 274 DCPCHHGGQCDHVTGQCHCTAGYMGDRC-QEECPFGSFGFQCSQHCDCHNGGQCSPTTGA 332
Query: 612 CLCHSGWKGAECD--------------VPTNQCIDVACSNHGTCITGTCICNPGYKGESC 657
C C G+KG C +P D S H +TG C C PG+ G C
Sbjct: 333 CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHP--VTGACTCQPGWSGHHC 390
Query: 658 EEV--------DCMDP-TCSGRGVC--VRGECHCSVGWGGTNCET--------PRATCLD 698
E C P TC C + G C C+ G+ G C P + +
Sbjct: 391 NESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSIC 450
Query: 699 QCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQR 758
C+ GT P G C+C W G DC++ G G+ +C C +G
Sbjct: 451 SCNNGGTCSPVDGSCTCKEGWQGLDCTL---PCPSGTWGLNCNESCTCANG--------A 499
Query: 759 ACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWH 818
AC P DG C C+PGW G+ C + D C C+ + D H
Sbjct: 500 ACSP--------IDGSCSCTPGWLGDTCELP-CPDGTFGLNCSEHCDCSHADGCDPVTGH 550
Query: 819 CVCQLGWRGAGCDTS 833
C C GW G CD++
Sbjct: 551 CCCLAGWTGIRCDST 565
Score = 90.5 bits (223), Expect = 2e-17
Identities = 74/250 (29%), Positives = 99/250 (39%), Gaps = 62/250 (24%)
Query: 569 NCYGNGDCI--SGTCHCFLGFLGPDCGRASCPVLCSGNG---------------QYMKGR 611
+C G C G+C C GF GP C R CP G+G ++ G
Sbjct: 580 SCENGGSCSPEDGSCECAPGFRGPLCQRI-CPPGFYGHGCAQPCPLCVHSSRPCHHISGI 638
Query: 612 CLCHSGWKGAECDVPT------NQCIDV-ACSNHGTC--ITGTCICNPGYKGESCEEV-- 660
C C G+ GA C+ C + +C+N+GTC I G+C C PG+ G+ C +
Sbjct: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACP 698
Query: 661 -DCMDPTCSGRGVCVRGE--------CHCSVGWGGTNCETPRATC---------LDQCSG 702
P C C G CHC+ GW G C T R + QC
Sbjct: 699 PGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC-TQRCPAAFFGKDCGRVCQCQN 757
Query: 703 HGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHG---VC----------VGGTCRCEDG 749
+ +G C+C +TG C + CA G+G +C V GTC C G
Sbjct: 758 GASCDHISGKCTCRTGFTGQHCE-QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPG 816
Query: 750 WMGAACDQRA 759
+ G CDQ A
Sbjct: 817 FKGIRCDQAA 826
Score = 82.0 bits (201), Expect = 7e-15
Identities = 65/194 (33%), Positives = 80/194 (41%), Gaps = 34/194 (17%)
Query: 648 CNPGY--KGESCEEVDCMDPTCSGRGVCVRGE-CHCSVGWGGTNCET--------PRATC 696
C PGY G+ C + C + GR CV + CHC GWGG +C + P +
Sbjct: 88 CCPGYYESGDFCIPL-CTEECVHGR--CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
Query: 697 LDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACD 756
QC P TG C C + G C E+CA G HG C+C GA+CD
Sbjct: 145 RCQCQNGALCNPITGACVCAAGFRGWRCE-ELCAP--GTHGKGCQLPCQCRH---GASCD 198
Query: 757 QRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNG 816
RA CA T + C PG +G HC + CP C G C + G
Sbjct: 199 PRAGECLCAPGYTGVYCEELCPPGSHGAHCELR----------CP--CQNGGTCH-HITG 245
Query: 817 WHCVCQLGWRGAGC 830
C C GW GA C
Sbjct: 246 -ECACPPGWTGAVC 258
Score = 63.9 bits (154), Expect = 2e-09
Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 31/122 (25%)
Query: 569 NCYGNGDCIS--GTCHCFLG-------------FLGPDCGRASCPVLCSGNGQYMKGRCL 613
+C+ C + G CHC G F G DCGR C + ++ G+C
Sbjct: 711 SCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV-CQCQNGASCDHISGKCT 769
Query: 614 CHSGWKGAECDVPTNQCID----------VACSNHGTC--ITGTCICNPGYKGESCEEVD 661
C +G+ G C+ +C C N+ TC +TGTC C+PG+KG C++
Sbjct: 770 CRTGFTGQHCE---QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
Query: 662 CM 663
M
Sbjct: 827 LM 828
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 127 bits (319), Expect = 2e-28
Identities = 99/332 (29%), Positives = 125/332 (37%), Gaps = 62/332 (18%)
Query: 567 PSNCYGNGDCIS-GTCHCFLGFLG-------------PDCGRASCPVLCSGNGQYMKGRC 612
P C + C+ G C C GF G PDC R SCP G + G C
Sbjct: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC-RESCPCHPHGQCEPATGAC 118
Query: 613 LCHSGWKGAECDVPTNQCIDVACSNHGTC--ITGTCICNPGYKGESCEEVDCMDPTCSGR 670
C + GA C+ P AC HG C TG C C PG+ +C C T + R
Sbjct: 119 QCQADRWGARCEFP------CACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171
Query: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEIC 729
G C C GW G C +C+ HG+ D+G C+C P W G +C +
Sbjct: 172 CEQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222
Query: 730 AADC-GGHGVCVGGTCRCEDGWMGAACD---------QRACHP--RCAEHGTCR--DGKC 775
+C G G C C G+ GA C+ + H RC + C G C
Sbjct: 223 -CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281
Query: 776 E-CSPGWNGEHC---TIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCV-CQLGWRGAGC 830
E C PGWNG C + ++ CP C C D HC C GW G C
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPH-CRHGEACEPDTG--HCQRCDPGWLGPRC 338
Query: 831 DTSMETA-----CGDSKDNDGDGLVDCMDPDC 857
+ T CG + G D + DC
Sbjct: 339 EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDC 370
Score = 115 bits (287), Expect = 8e-25
Identities = 85/311 (27%), Positives = 112/311 (36%), Gaps = 49/311 (15%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
C +G D +G CHC G+ C R + + G C+C GW G C
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESC-EEVDCMDPTCSGRGVCVRGECHCSVGW 684
N C C +G C C PG+ G C ++ +C+ CS GEC C G+
Sbjct: 193 RCN-CHGSPCEQD----SGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPGF 243
Query: 685 GGTNCETP---------RATCLDQCSGHGTFLPDTGLC-SCDPSWTGHDCSIEICAADCG 734
G CE P A +C + PDTG C SC+P W G C
Sbjct: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP------- 296
Query: 735 GHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCE-CSPGWNGEHCTIAHYLD 793
C G G +C+Q+ H R E G C+ C PGW G C
Sbjct: 297 -----------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344
Query: 794 RVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCM 853
E C C + + D CVC G+ G C+ S + +C
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---------NCS 395
Query: 854 DPDCCLQPLCH 864
P C + LCH
Sbjct: 396 VPCECPEGLCH 406
Score = 105 bits (263), Expect = 5e-22
Identities = 78/258 (30%), Positives = 97/258 (37%), Gaps = 52/258 (20%)
Query: 614 CHSGW--KGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEE--------VDC 662
C +GW K EC +P + D AC C+ G C C PG+ G C DC
Sbjct: 41 CCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 663 MDP-TCSGRGVC--VRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSW 719
+ C G C G C C G CE P A C HG P TG+C C+P W
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-----CGPHGRCDPATGVCHCEPGW 154
Query: 720 TGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGT-CR--DGKCE 776
C G C C+ GW G R C RC HG+ C G+C
Sbjct: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209
Query: 777 CSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD----- 831
C PGW G C ++ C + GRC+ C C G+RGA C+
Sbjct: 210 CRPGWWGPEC----------QQQCECV---RGRCS--AASGECTCPPGFRGARCELPCPA 254
Query: 832 ----TSMETACGDSKDND 845
+CG K N+
Sbjct: 255 GSHGVQCAHSCGRCKHNE 272
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 127 bits (319), Expect = 2e-28
Identities = 99/332 (29%), Positives = 125/332 (37%), Gaps = 62/332 (18%)
Query: 567 PSNCYGNGDCIS-GTCHCFLGFLG-------------PDCGRASCPVLCSGNGQYMKGRC 612
P C + C+ G C C GF G PDC R SCP G + G C
Sbjct: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC-RESCPCHPHGQCEPATGAC 118
Query: 613 LCHSGWKGAECDVPTNQCIDVACSNHGTC--ITGTCICNPGYKGESCEEVDCMDPTCSGR 670
C + GA C+ P AC HG C TG C C PG+ +C C T + R
Sbjct: 119 QCQADRWGARCEFP------CACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171
Query: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEIC 729
G C C GW G C +C+ HG+ D+G C+C P W G +C +
Sbjct: 172 CEQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222
Query: 730 AADC-GGHGVCVGGTCRCEDGWMGAACD---------QRACHP--RCAEHGTCR--DGKC 775
+C G G C C G+ GA C+ + H RC + C G C
Sbjct: 223 -CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281
Query: 776 E-CSPGWNGEHC---TIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCV-CQLGWRGAGC 830
E C PGWNG C + ++ CP C C D HC C GW G C
Sbjct: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPH-CRHGEACEPDTG--HCQRCDPGWLGPRC 338
Query: 831 DTSMETA-----CGDSKDNDGDGLVDCMDPDC 857
+ T CG + G D + DC
Sbjct: 339 EDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDC 370
Score = 115 bits (287), Expect = 8e-25
Identities = 85/311 (27%), Positives = 112/311 (36%), Gaps = 49/311 (15%)
Query: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
C +G D +G CHC G+ C R + + G C+C GW G C
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESC-EEVDCMDPTCSGRGVCVRGECHCSVGW 684
N C C +G C C PG+ G C ++ +C+ CS GEC C G+
Sbjct: 193 RCN-CHGSPCEQD----SGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPGF 243
Query: 685 GGTNCETP---------RATCLDQCSGHGTFLPDTGLC-SCDPSWTGHDCSIEICAADCG 734
G CE P A +C + PDTG C SC+P W G C
Sbjct: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP------- 296
Query: 735 GHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCE-CSPGWNGEHCTIAHYLD 793
C G G +C+Q+ H R E G C+ C PGW G C
Sbjct: 297 -----------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCE-DPCPT 344
Query: 794 RVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDGLVDCM 853
E C C + + D CVC G+ G C+ S + +C
Sbjct: 345 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---------NCS 395
Query: 854 DPDCCLQPLCH 864
P C + LCH
Sbjct: 396 VPCECPEGLCH 406
Score = 105 bits (263), Expect = 5e-22
Identities = 78/258 (30%), Positives = 97/258 (37%), Gaps = 52/258 (20%)
Query: 614 CHSGW--KGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEE--------VDC 662
C +GW K EC +P + D AC C+ G C C PG+ G C DC
Sbjct: 41 CCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 663 MDP-TCSGRGVC--VRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSW 719
+ C G C G C C G CE P A C HG P TG+C C+P W
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-----CGPHGRCDPATGVCHCEPGW 154
Query: 720 TGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGT-CR--DGKCE 776
C G C C+ GW G R C RC HG+ C G+C
Sbjct: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209
Query: 777 CSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD----- 831
C PGW G C ++ C + GRC+ C C G+RGA C+
Sbjct: 210 CRPGWWGPEC----------QQQCECV---RGRCS--AASGECTCPPGFRGARCELPCPA 254
Query: 832 ----TSMETACGDSKDND 845
+CG K N+
Sbjct: 255 GSHGVQCAHSCGRCKHNE 272
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 120 bits (301), Expect = 2e-26
Identities = 62/157 (39%), Positives = 76/157 (48%), Gaps = 10/157 (6%)
Query: 635 CSNHGTCITGT-CICNPGYKGESCEEVDCMDPTCSGRGVCVR-GECHCSVGWGGTNCETP 692
C N G C C C G+ G CE+ C P C G+CV G C C G+ G NC+
Sbjct: 186 CRNGGFCNERRICECPDGFHGPHCEKALCT-PRCMNGGLCVTPGFCICPPGFYGVNCD-- 242
Query: 693 RATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVCVGGT-CRCEDGW 750
+A C C GT F P G C C P G C I C C G C+G + C+C G+
Sbjct: 243 KANCSTTCFNGGTCFYP--GKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGY 300
Query: 751 MGAACDQRACHPRCAEHGTCRD-GKCECSPGWNGEHC 786
G C + C P C HGTC + KC+C GW+G HC
Sbjct: 301 QGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHC 337
Score = 106 bits (264), Expect = 4e-22
Identities = 60/164 (36%), Positives = 71/164 (43%), Gaps = 11/164 (6%)
Query: 566 CPSNCYGNGDCISGT-CHCFLGFLGPDCGRASCPVLCSGNGQYMK-GRCLCHSGWKGAEC 623
CP C G C C C GF GP C +A C C G + G C+C G+ G C
Sbjct: 182 CPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNC 241
Query: 624 DVPTNQCIDVACSNHGTCI-TGTCICNPGYKGESCEEVDCMDPTCSGRGVCV-RGECHCS 681
D C N GTC G CIC PG +GE CE C P C G C+ + +C CS
Sbjct: 242 DKAN---CSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQP-CRNGGKCIGKSKCKCS 297
Query: 682 VGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCS 725
G+ G C P C C HGT + C C W G C+
Sbjct: 298 KGYQGDLCSKP--VCEPGCGAHGT-CHEPNKCQCQEGWHGRHCN 338
Score = 104 bits (260), Expect = 1e-21
Identities = 58/171 (33%), Positives = 79/171 (46%), Gaps = 11/171 (6%)
Query: 592 CGRASCPVLCSGNGQYMKGR-CLCHSGWKGAECDVPTNQCIDVACSNHGTCIT-GTCICN 649
C +A CP C G + R C C G+ G C+ C N G C+T G CIC
Sbjct: 177 CQQAECPGGCRNGGFCNERRICECPDGFHGPHCE---KALCTPRCMNGGLCVTPGFCICP 233
Query: 650 PGYKGESCEEVDCMDPTCSGRGVCVR-GECHCSVGWGGTNCETPRATCLDQCSGHGTFLP 708
PG+ G +C++ +C TC G C G+C C G G CE + C C G +
Sbjct: 234 PGFYGVNCDKANC-STTCFNGGTCFYPGKCICPPGLEGEQCEISK--CPQPCRNGGKCIG 290
Query: 709 DTGLCSCDPSWTGHDCSIEICAADCGGHGVC-VGGTCRCEDGWMGAACDQR 758
+ C C + G CS +C CG HG C C+C++GW G C++R
Sbjct: 291 KSK-CKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHGRHCNKR 340
Score = 85.1 bits (209), Expect = 9e-16
Identities = 54/167 (32%), Positives = 71/167 (42%), Gaps = 24/167 (14%)
Query: 685 GGTNCETPR-----ATCLD-QCSG---HGTFLPDTGLCSCDPSWTGHDCSIEICAADCGG 735
G T +TP+ TC +C G +G F + +C C + G C +C C
Sbjct: 161 GNTILQTPQNAIFFKTCQQAECPGGCRNGGFCNERRICECPDGFHGPHCEKALCTPRCMN 220
Query: 736 HGVCVG-GTCRCEDGWMGAACDQRACHPRCAEHGTC-RDGKCECSPGWNGEHCTIAHYLD 793
G+CV G C C G+ G CD+ C C GTC GKC C PG GE C I+
Sbjct: 221 GGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISK--- 277
Query: 794 RVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSM-ETACG 839
CP C G+C + C C G++G C + E CG
Sbjct: 278 ------CPQPCRNGGKC---IGKSKCKCSKGYQGDLCSKPVCEPGCG 315
Score = 63.2 bits (152), Expect = 4e-09
Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 565 NCPSNCYGNGDCI-SGTCHCFLGFLGPDCGRASCPVLCSGNGQYM-KGRCLCHSGWKGAE 622
NC + C+ G C G C C G G C + CP C G+ + K +C C G++G
Sbjct: 245 NCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDL 304
Query: 623 CDVPTNQCIDVACSNHGTC-ITGTCICNPGYKGESCEE 659
C P + C HGTC C C G+ G C +
Sbjct: 305 CSKPV---CEPGCGAHGTCHEPNKCQCQEGWHGRHCNK 339
Score = 47.4 bits (111), Expect = 2e-04
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 2/64 (3%)
Query: 563 VDNCPSNCYGNGDCI-SGTCHCFLGFLGPDCGRASCPVLCSGNGQ-YMKGRCLCHSGWKG 620
+ CP C G CI C C G+ G C + C C +G + +C C GW G
Sbjct: 275 ISKCPQPCRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGAHGTCHEPNKCQCQEGWHG 334
Query: 621 AECD 624
C+
Sbjct: 335 RHCN 338
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 120 bits (301), Expect = 2e-26
Identities = 98/350 (28%), Positives = 131/350 (37%), Gaps = 57/350 (16%)
Query: 541 LAFYNDGKESEVVSFLTTAIESVDNCPSN--------CYGNGDCISG------TCHCFLG 586
+ F ND +V+ T + V C C G G C + +C C
Sbjct: 282 IGFVNDSVTKSIVALRLTLVVKVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQ 341
Query: 587 FLGP------DCGRASCP--VLCSGNGQYMKGR---CLCHSGWKGAECDVPTNQCIDVAC 635
++G C R C C + G C+C G+ G C + CI C
Sbjct: 342 YVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPC 401
Query: 636 SNHGTCITG----TCICNPGYKGESCEE-VD-CMDPTCSGRGVC----VRGECHCSVGWG 685
N TCI+ TC C GY G +CEE VD C C G C V C+CS G+
Sbjct: 402 RNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFT 461
Query: 686 GTNCETPRATCLDQCSGHGTF--LPDTGLCSCDPSWTGHDCSIEI---CAADCGGHGVCV 740
G C C HGT + + C CDP + G C E +A C C
Sbjct: 462 GPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCR 521
Query: 741 ----GGTCRCEDGWMGAACD---QRACHPRCAEHGTCR----DGKCECSPGWNGEHCTIA 789
G C C + G C+ + C TC +G C C+PG+ GE C I
Sbjct: 522 DLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDID 581
Query: 790 HYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACG 839
+ E C+ G C NG++C C GW GA C+ ++ G
Sbjct: 582 ------INECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSG 625
Score = 101 bits (251), Expect = 1e-20
Identities = 84/305 (27%), Positives = 112/305 (36%), Gaps = 55/305 (18%)
Query: 619 KGAECDVPTNQCIDVACSNHGTCITG------TCICNPGYKGESCEEVD-CMDPTCSGRG 671
K + C + D+ CS G C T +C C Y G CEE D C C
Sbjct: 303 KVSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNA 362
Query: 672 VCVRGE---------CHCSVGWGGTNCETPRATC-LDQCSGHGTFLPDTG--LCSCDPSW 719
C+ C C G+ G C++ C LD C T + C C +
Sbjct: 363 SCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGY 422
Query: 720 TGHDCS--IEICAAD-CGGHGVC----VGGTCRCEDGWMGAACDQRA--CHPRCAEHGTC 770
G C ++ CA+ C +G C V TC C G+ G C Q C HGTC
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTC 482
Query: 771 RDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWR 826
R KC C PG++G +C + E C C +NG+ CVC ++
Sbjct: 483 RSVGTSYKCLCDPGYHGLYC------EEEYNECLSAPCLNAATCRDLVNGYECVCLAEYK 536
Query: 827 GAGC----DTSMETACGDSKDNDGDGL------------VDC-MDPDCCLQPLCHINPLC 869
G C D +C + D DGL +C +D + C CH C
Sbjct: 537 GTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSC 596
Query: 870 LGSPN 874
L PN
Sbjct: 597 LDQPN 601
Score = 45.4 bits (106), Expect = 8e-04
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT--------CICNPGYKGESCEE 659
C C +G GA C + + C C +HG C + + CICN GY+G +CE+
Sbjct: 80 CTCPAGISGANCQLVADPCASNPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 33.9 bits (76), Expect = 2.3
Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 19/120 (15%)
Query: 721 GHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRA----CHPRCA-EHGTCRDGKC 775
G + + AA G C CR G C R HP A E G C
Sbjct: 30 GSSLANPVPAAPLSAPGPCAAQPCR-----NGGVCTSRPEPDPQHPAPAGEPGY----SC 80
Query: 776 ECSPGWNGEHCTIAHYLDRVVKEGCP-GLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSM 834
C G +G +C + D C G C+ + + D G+ C+C G+ G C+ ++
Sbjct: 81 TCPAGISGANCQLV--ADPCASNPCHHGNCSSSSSSSSD--GYLCICNEGYEGPNCEQAL 136
Score = 33.9 bits (76), Expect = 2.3
Identities = 22/87 (25%), Positives = 27/87 (31%), Gaps = 6/87 (6%)
Query: 644 GTCICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLD----- 698
G C P G C DP C C G G NC+ C
Sbjct: 46 GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 699 -QCSGHGTFLPDTGLCSCDPSWTGHDC 724
CS + D LC C+ + G +C
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNC 132
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 120 bits (300), Expect = 2e-26
Identities = 102/361 (28%), Positives = 134/361 (37%), Gaps = 57/361 (15%)
Query: 563 VDNCPSN-CYGNGDCISGT----CHCFLGFLGPDCGRASCPV---LCSGNGQYM----KG 610
V+ C S C G C G C C GF GP C A P C GQ
Sbjct: 312 VNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSA 371
Query: 611 RCLCHSGWKGAECDVPTNQCIDVACSNHGTCI----TGTCICNPGYKGESCEEVD----- 661
C+C +G+ GA C++ + C C N G+C+ TC+C +KG CE D
Sbjct: 372 VCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPD 431
Query: 662 -CMDPTCSGRGVCVRGE----CHCSVGWGGTNCETPRATCLDQCSGHGTFL-PDTGLCSC 715
C+ C G CV + C C G+ G +C R +C G L +T LC C
Sbjct: 432 ACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRE-RVPDDCECRNGGRCLGANTTLCQC 490
Query: 716 DPSWTGHDCSIEICAADCGGHGVCV-GGTCRCEDGWMGAAC--DQRACH--PRCAEHGTC 770
+ G C EI A C + C GG C G C D A H P + C
Sbjct: 491 PLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC 550
Query: 771 RDG----------KCECSPGWNGEHCTIAHYLDRVVKEGCP-GLCNGNGRCTLDLNGWHC 819
+G CEC G++G+HC ++ C G C G C +HC
Sbjct: 551 FNGGSCDAHDDSYTCECPRGFHGKHC------EKARPHLCSSGPCRNGGTCKEAGGEYHC 604
Query: 820 VCQLGWRGAGCDTSMETACGDSKDNDGD------GLVDCMDPDCCLQPLCHINPL-CLGS 872
C + G C+ +C ++G G C P C I P C S
Sbjct: 605 SCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
Query: 873 P 873
P
Sbjct: 665 P 665
Score = 95.1 bits (235), Expect = 8e-19
Identities = 98/350 (28%), Positives = 129/350 (36%), Gaps = 61/350 (17%)
Query: 566 CPSN-CYGNGDCI----SGTCHCFLGFLGPDCGRASCPVLCSG----NGQYMKG-----R 611
C S+ C+ G C S TC C GF G C +A P LCS NG K
Sbjct: 545 CDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKAR-PHLCSSGPCRNGGTCKEAGGEYH 603
Query: 612 CLCHSGWKGAECDV-PTNQCIDVACSNHGTCI----TGTCICNPGYKGESCEEVD--CMD 664
C C + G C++ + C C N GTC C C PG+ G CE C
Sbjct: 604 CSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFR 663
Query: 665 PTCSGRGVCVRGE----CHCSVGWGGTNCET------PRATCLDQCSGHGTFLPDTGLCS 714
C G C + CHC G+ G C+ P +GT L L +
Sbjct: 664 SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYA 723
Query: 715 CDPSWTGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGK 774
CD G+ S C HGV +C + D+ P C G+C+D
Sbjct: 724 CD---RGYSLSAPSRIRVCQPHGVW-SEPPQCLE------IDECRSQP-CLHGGSCQDRV 772
Query: 775 ----CECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
C CS G+ G HC L+R P C G C + C C G+ G C
Sbjct: 773 AGYLCLCSTGYEGAHCE----LERDECRAHP--CRNGGSCRNLPGAYVCRCPAGFVGVHC 826
Query: 831 DTSMETACGDS------KDNDGDGLVDCMDPDCCLQPLCH-INPLCLGSP 873
+T ++ AC S + G G C+ P+ C ++ C SP
Sbjct: 827 ETEVD-ACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSP 875
Score = 91.7 bits (226), Expect = 9e-18
Identities = 93/380 (24%), Positives = 122/380 (32%), Gaps = 92/380 (24%)
Query: 574 GDCISGTCHCFLGFLGPDCGRASCPVLC-SGNGQYMKGRCLCHSGWKGAECDVPTNQCID 632
G C T C L P C C +GN Y C C SG+ G C + N+C
Sbjct: 263 GGCGHTTSVCLA--LRPCLNGGKCIDDCVTGNPSYT---CSCLSGFTGRRCHLDVNECAS 317
Query: 633 VACSNHGTCITG------------------------------------------TCICNP 650
C N GTC G C+C
Sbjct: 318 QPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQA 377
Query: 651 GYKGESCE--EVDCMDPTCSGRGVCV----RGECHCSVGWGGTNCET-----PRATCLDQ 699
GY G +CE DC C G CV C C+ + G CET P A
Sbjct: 378 GYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP 437
Query: 700 CSGHGTFL-PDTG-LCSCDPSWTGHDCSIEI-CAADCGGHGVCVGGT---CRCEDGWMGA 753
C GT + D G +C C + G DC + +C G C+G C+C G+ G
Sbjct: 438 CHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGL 497
Query: 754 ACDQRACHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGN-----G 808
C+ C + C DG G G + + H D P C+ + G
Sbjct: 498 LCEFEITAMPCNMNTQCPDGGYCMEHG--GSYLCVCH-TDHNASHSLPSPCDSDPCFNGG 554
Query: 809 RCTLDLNGWHCVCQLGWRGAGCDTSMETAC--------GDSKDNDGDGLVDCM------- 853
C + + C C G+ G C+ + C G K+ G+ C
Sbjct: 555 SCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRH 614
Query: 854 ----DPDCCLQPLCHINPLC 869
PD C CH C
Sbjct: 615 CEIGKPDSCASGPCHNGGTC 634
Score = 87.4 bits (215), Expect = 2e-16
Identities = 89/324 (27%), Positives = 115/324 (35%), Gaps = 73/324 (22%)
Query: 570 CYGNGDCISGT----CHCFLGFLGPDCGRASCPVLCSG---NG----QYM-KGRCLCHSG 617
C G C C C F G C SG NG Y+ K +C C G
Sbjct: 589 CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG 648
Query: 618 WKGAECDVPTNQCIDVACSNHGTCITGT----CICNPGYKGESCE-EVDCMDPT------ 666
+ G C++ + C C N GTC C C GY G C+ EVDC P
Sbjct: 649 FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHAT 708
Query: 667 --CSGRGVCVRGECHCSVGWG-------------GTNCETPRATCLDQCSG----HGTFL 707
+G + C G+ G E P+ +D+C HG
Sbjct: 709 LRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC 768
Query: 708 PDTG---LCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR---------CEDGWMGAAC 755
D LC C + G C +E +C H GG+CR C G++G C
Sbjct: 769 QDRVAGYLCLCSTGYEGAHCELE--RDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHC 826
Query: 756 DQR--ACHPRCAEHG-TCRDGK----CECSPGWNGEHCTIAHYLDRVVKEGC-PGLCNGN 807
+ AC +HG C G C C + G HC V + C C G
Sbjct: 827 ETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHC-------ETVSDPCFSSPCGGR 879
Query: 808 GRCTLDLNGWH-CVCQLGWRGAGC 830
G C L NG H C C++G+ G C
Sbjct: 880 GYC-LASNGSHSCTCKVGYTGEDC 902
Score = 75.1 bits (183), Expect = 9e-13
Identities = 46/130 (35%), Positives = 63/130 (48%), Gaps = 13/130 (10%)
Query: 612 CLCHSGWKGAECDVPTNQCIDVACSNHGTC--ITG--TCICNPGYKGESCE-EVDCMDPT 666
CLC +G++GA C++ ++C C N G+C + G C C G+ G CE EVD D +
Sbjct: 777 CLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSS 836
Query: 667 -CSGRGVCVRGE----CHCSVGWGGTNCETPRATCLDQ-CSGHGTFLPDTG--LCSCDPS 718
C G C G C C + G +CET C C G G L G C+C
Sbjct: 837 PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVG 896
Query: 719 WTGHDCSIEI 728
+TG DC+ E+
Sbjct: 897 YTGEDCAKEL 906
Score = 62.4 bits (150), Expect = 6e-09
Identities = 50/186 (26%), Positives = 67/186 (36%), Gaps = 42/186 (22%)
Query: 721 GHDCSIEICAADCGGHGVCVGG--------TCRCEDGWMGAAC--DQRACHPR-CAEHGT 769
GH S+ + C G C+ TC C G+ G C D C + C GT
Sbjct: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGT 325
Query: 770 CRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGW 825
C G +C+C G+ G C A KE C G+C ++ CVCQ G+
Sbjct: 326 CTHGINSFRCQCPAGFGGPTCETAQS-PCDTKE-----CQHGGQCQVENGSAVCVCQAGY 379
Query: 826 RGAGCDTSMETACGDSKDNDGD-----GLVDCM----------------DPDCCLQPLCH 864
GA C+ ++ D N G G C+ PD CL CH
Sbjct: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCH 439
Query: 865 INPLCL 870
C+
Sbjct: 440 NGGTCV 445
Score = 39.7 bits (91), Expect = 0.042
Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 5/39 (12%)
Query: 624 DVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE 658
+VP N C + C N GTC+ G +C C PG+KG CE
Sbjct: 1306 NVPGN-CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 118 bits (296), Expect = 7e-26
Identities = 91/282 (32%), Positives = 116/282 (41%), Gaps = 36/282 (12%)
Query: 579 GTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCID-VACSN 637
G C C +G+ G C C +C C GW G C+ N C C N
Sbjct: 241 GECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKN 300
Query: 638 HGTCI-TG----TCICNPGYKGESCE-EVDCMDPT-CSGRGVCVRGE----CHCSVGWGG 686
TC TG TC C PGY G +CE +D DP+ C G C E C C G+ G
Sbjct: 301 GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYG 360
Query: 687 TNCETPRATCLD-QC--SGHGTFLPDTGL-CSCDPSWTGHDCS--IEICAAD-CGGHGVC 739
CE TC D C G + PD G C C ++G +C I+ C++ C C
Sbjct: 361 KICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC 420
Query: 740 V----GGTCRCEDGWMGAACDQRA---CHPRCAEHGTCRDG----KCECSPGWNGEHCTI 788
V CRC+ G+ G CD CA GTCRDG C C PG+ G +C+
Sbjct: 421 VDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSA 480
Query: 789 AHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGC 830
+ R E P C+ C + + C C G+ G C
Sbjct: 481 P--VSRC--EHAP--CHNGATCHERGHRYVCECARGYGGPNC 516
Score = 105 bits (263), Expect = 5e-22
Identities = 76/265 (28%), Positives = 107/265 (40%), Gaps = 53/265 (20%)
Query: 570 CYGNGDCISGTC------HCFLGFLGPDCGR--------------ASCPVLCSGNGQYMK 609
C C+ GTC +C G+ G C + A+C +G G Y
Sbjct: 257 CIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTN--TGQGSYT- 313
Query: 610 GRCLCHSGWKGAECDVPTNQCIDVACSNHGTCI----TGTCICNPGYKGESCE--EVDCM 663
C C G+ GA C++ ++C C N G+C + +C C PG+ G+ CE + C
Sbjct: 314 --CSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCA 371
Query: 664 DPTCSGRGVCVRG-----ECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTG---LCSC 715
D C G C C C VG+ G NCE C +G D G LC C
Sbjct: 372 DGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRC 431
Query: 716 DPSWTGHDC--SIEICAAD-CGGHGVCVGG----TCRCEDGWMGAACD---QRACHPRCA 765
++G C +++ CA+ C G C G +C C G+ G C R H C
Sbjct: 432 QAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 766 EHGTCRDG----KCECSPGWNGEHC 786
TC + CEC+ G+ G +C
Sbjct: 492 NGATCHERGHRYVCECARGYGGPNC 516
Score = 103 bits (256), Expect = 3e-21
Identities = 76/275 (27%), Positives = 109/275 (39%), Gaps = 49/275 (17%)
Query: 609 KGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEEV----DCM 663
+G +C+ GWKG C P C+ HG C G C C G++G C+E C+
Sbjct: 207 RGEKVCNPGWKGPYCTEPI--CLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCL 264
Query: 664 DPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGH-----GTFLPDTG----LCS 714
TC +C+C GWGG C L+ C+ H G +TG CS
Sbjct: 265 HGTCQQPW-----QCNCQEGWGGLFCNQD----LNYCTHHKPCKNGATCTNTGQGSYTCS 315
Query: 715 CDPSWTGHDCSIEICAAD---CGGHGVCV----GGTCRCEDGWMGAACDQRA---CHPRC 764
C P +TG C + I D C G C +C C G+ G C+ A C
Sbjct: 316 CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPC 375
Query: 765 AEHGTCRDG-----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 819
G C D C C G++G +C ++ + C+ +C + + C
Sbjct: 376 FNGGRCSDSPDGGYSCRCPVGYSGFNC------EKKIDYCSSSPCSNGAKCVDLGDAYLC 429
Query: 820 VCQLGWRGAGCDTSMETACGDSKDNDG---DGLVD 851
CQ G+ G CD +++ N G DG+ D
Sbjct: 430 RCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND 464
Score = 101 bits (252), Expect = 9e-21
Identities = 81/271 (29%), Positives = 109/271 (40%), Gaps = 40/271 (14%)
Query: 611 RCLCHSGWKGAECDVPTNQCIDVACSNHGTC-ITGTCICNPGYKGESCEEVDCMDPTCSG 669
R +C + G C V D H TC G +CNPG+KG C E C+
Sbjct: 176 RFVCDEHYYGEGCSVFCRPRDDAF--GHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQ 233
Query: 670 RGVCVR-GECHCSVGWGGTNCE--TPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSI 726
G C + GEC C VGW G C+ CL HGT C+C W G C+
Sbjct: 234 HGFCDKPGECKCRVGWQGRYCDECIRYPGCL-----HGT-CQQPWQCNCQEGWGGLFCNQ 287
Query: 727 EICAADCGGHGVCVGG-----------TCRCEDGWMGAACDQ--RACHPR-CAEHGTCRD 772
++ C H C G TC C G+ GA C+ C P C G+C D
Sbjct: 288 DL--NYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTD 345
Query: 773 ----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLN-GWHCVCQLGWRG 827
C C PG+ G+ C ++ G C GRC+ + G+ C C +G+ G
Sbjct: 346 LENSYSCTCPPGFYGKICELS------AMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 828 AGCDTSMETACGDSKDNDGDGLVDCMDPDCC 858
C+ ++ C S ++G VD D C
Sbjct: 400 FNCEKKID-YCSSSPCSNGAKCVDLGDAYLC 429
Score = 80.5 bits (197), Expect = 2e-14
Identities = 60/201 (29%), Positives = 79/201 (39%), Gaps = 27/201 (13%)
Query: 680 CSVGWGGTNCET---PRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGG- 735
C + G C PR D GH T + G C+P W G C+ IC C
Sbjct: 179 CDEHYYGEGCSVFCRPR----DDAFGHFT-CGERGEKVCNPGWKGPYCTEPICLPGCDEQ 233
Query: 736 HGVC-VGGTCRCEDGWMGAACDQRACHPRCAEHGTCRD-GKCECSPGWNGEHCT-----I 788
HG C G C+C GW G CD+ +P C HGTC+ +C C GW G C
Sbjct: 234 HGFCDKPGECKCRVGWQGRYCDECIRYPGCL-HGTCQQPWQCNCQEGWGGLFCNQDLNYC 292
Query: 789 AHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGDG 848
H+ + K G G G T C C+ G+ GA C+ ++ C S +G
Sbjct: 293 THH--KPCKNGATCTNTGQGSYT-------CSCRPGYTGATCELGID-ECDPSPCKNGGS 342
Query: 849 LVDCMDPDCCLQPLCHINPLC 869
D + C P +C
Sbjct: 343 CTDLENSYSCTCPPGFYGKIC 363
Score = 70.9 bits (172), Expect = 2e-11
Identities = 46/147 (31%), Positives = 65/147 (44%), Gaps = 30/147 (20%)
Query: 570 CYGNGDCISG-----TCHCFLGFLGPDCGR-----ASCPVLCSGNGQYMK----GRCLCH 615
C+ G C +C C +G+ G +C + +S P CS + + C C
Sbjct: 375 CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSP--CSNGAKCVDLGDAYLCRCQ 432
Query: 616 SGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGES-------CEEVDCMD 664
+G+ G CD + C C+N GTC G +C C PGY G + CE C +
Sbjct: 433 AGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHN 492
Query: 665 -PTCSGRGVCVRGECHCSVGWGGTNCE 690
TC RG R C C+ G+GG NC+
Sbjct: 493 GATCHERG--HRYVCECARGYGGPNCQ 517
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 118 bits (296), Expect = 7e-26
Identities = 94/347 (27%), Positives = 132/347 (38%), Gaps = 72/347 (20%)
Query: 564 DNCPSN-CYGNGDCI------SGTCHCFLGFLGP-------DCGRASCPV--LCSGNGQY 607
D C SN C G+ C+ S C C G+ G CG+ SC +C + Y
Sbjct: 72 DPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIY 131
Query: 608 MKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE-EVD- 661
C+C +G+ G C++ ++C C N C G +C C PGY+G C+ EVD
Sbjct: 132 PV--CICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE 189
Query: 662 CMDPTCSGRGVCV----RGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDT---GLCS 714
C C C+ R C C + G NCE C Q +G D C
Sbjct: 190 CASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
Query: 715 CDPSWTGHDCSI---EICAADCGGHGVCVGG----TCRCE-DGWMGAACD--QRACHPR- 763
C P + G C + E + C G+CV G +C C G+ G C+ C +
Sbjct: 250 CAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 764 CAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTL------- 812
C + TC D C C PG+ G C I + E C NG C
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEID------LNECNSNPCQSNGECVELSSEKQY 363
Query: 813 -------------DLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDG 846
+ +G+ C+CQ G+ G C+ + + N G
Sbjct: 364 GRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGG 410
Score = 103 bits (258), Expect = 2e-21
Identities = 79/292 (27%), Positives = 118/292 (40%), Gaps = 44/292 (15%)
Query: 587 FLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDVPTNQCIDVACSNHGTC----I 642
F P G A+C V G ++ C C G+ G C+ C +C + G C I
Sbjct: 75 FSNPCQGSATC-VNTPGERSFL---CKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPI 130
Query: 643 TGTCICNPGYKGESCE--EVDCMDPTCSGRGVCVRG----ECHCSVGWGGTNCETPRATC 696
CIC GY G CE +C C VC G C C G+ G +C+ C
Sbjct: 131 YPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC 190
Query: 697 L-DQCSGHGTFLPDTG--LCSCDPSWTGHDCSIEICAADCGGHGVCVGGTCR-------- 745
D C T L + G C C +++G +C +EI +C G TC+
Sbjct: 191 ASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEI--DECWSQPCLNGATCQDALGAYFC 248
Query: 746 -CEDGWMGAAC----DQRACHPRCAEHGTCRDGK----CECS-PGWNGEHCTIAHYLDRV 795
C G++G C D+ A P C G C DG+ C C+ G+ G HC + +
Sbjct: 249 DCAPGFLGDHCELNTDECASQP-CLHGGLCVDGENRYSCNCTGSGFTGTHC------ETL 301
Query: 796 VKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMETACGDSKDNDGD 847
+ C+ N C ++ + C C G+ GA C+ + + ++G+
Sbjct: 302 MPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGE 353
Score = 94.0 bits (232), Expect = 2e-18
Identities = 96/377 (25%), Positives = 135/377 (35%), Gaps = 112/377 (29%)
Query: 562 SVDNCPSN-CYGNGDC----ISGTCHCFLGFLGPDCGR-----ASCPVLCSGNGQYMKG- 610
++ +C N C G C I C C G+ G C AS P C G
Sbjct: 110 TIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHDECASSP--CQNGAVCQDGI 167
Query: 611 ---RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITG----TCICNPGYKGESCE-EVD- 661
C C G++G CD+ ++C C N TC+ TCIC Y G +CE E+D
Sbjct: 168 DGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDE 227
Query: 662 --------------------------------------CMDPTCSGRGVCVRGE----CH 679
C C G+CV GE C+
Sbjct: 228 CWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCN 287
Query: 680 CS-VGWGGTNCETPRATCLDQ-CSGHGTF--LPDTGLCSCDPSWTGHDCSIEI--CAAD- 732
C+ G+ GT+CET C + C + T D C C P +TG C I++ C ++
Sbjct: 288 CTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP 347
Query: 733 CGGHGVCV------------------------GGTCRCEDGWMGAACDQRACHPRCAEHG 768
C +G CV G C C+ G+ G C++ C+ +
Sbjct: 348 CQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDV--NECSSNP 405
Query: 769 TCRDGKCECSPGWNGEHCTIAHYLDRVVKEG--CPGL--------CNGNGRCTLDL---- 814
G CE PG HC + L R G C + C NG C
Sbjct: 406 CQNGGTCENLPGNYTCHCPFDN-LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQ 464
Query: 815 NGWHCVCQLGWRGAGCD 831
+G+ C+C G+ G+ C+
Sbjct: 465 HGFSCLCPSGYTGSLCE 481
Score = 84.7 bits (208), Expect = 1e-15
Identities = 74/307 (24%), Positives = 104/307 (33%), Gaps = 88/307 (28%)
Query: 619 KGAECDVPTNQCIDVACSNHGTCI-----------------------------------T 643
K + C+ +C+ +C N+ TC +
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 644 GTCI-----------CNPGYKGESCEEV--DCMDPTCSGRGVC----VRGECHCSVGWGG 686
TC+ C PGY G CE C +C G+C + C C G+ G
Sbjct: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
Query: 687 TNCETPRATCLDQCSGHGTFLPDTGL----CSCDPSWTGHDCSIEI--CAAD-CGGHGVC 739
CE C +G D G+ C C P + G C +E+ CA+D C C
Sbjct: 143 RFCEIDHDECASSPCQNGAVCQD-GIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
Query: 740 VGG----TCRCEDGWMGAACD---QRACHPRCAEHGTCRDGK----CECSPGWNGEHCTI 788
+ TC C + G C+ C TC+D C+C+PG+ G+HC +
Sbjct: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 789 AHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQ-LGWRGAGCDTSM----------ETA 837
E C G C N + C C G+ G C+T M
Sbjct: 262 N------TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNAT 315
Query: 838 CGDSKDN 844
C DS DN
Sbjct: 316 CEDSVDN 322
Score = 77.0 bits (188), Expect = 2e-13
Identities = 53/212 (25%), Positives = 80/212 (37%), Gaps = 41/212 (19%)
Query: 646 CICNPGYKGESCEEVDCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT 705
C NP G +CE++ C C +GW G +CE C HG
Sbjct: 1143 CNSNPCLHGGNCEDIYSSY------------HCSCPLGWSGKHCELNIDECFSNPCIHGN 1190
Query: 706 FLPDTGL--CSCDPSWTGHDCSIEI--CAA-DCGGHGVCV----GGTCRCEDGWMGAACD 756
C+C+P +TG +C ++I C + C C+ G +C C + G C
Sbjct: 1191 CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Query: 757 Q----------RACHPRCAEHGTCRDG----KCECSPGWNGEHCTIAHYLDRVVKEGCPG 802
Q + C G C + KC C PG+ GE C ++ + E
Sbjct: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWC------EKDIDECASD 1304
Query: 803 LCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSM 834
C G C LN + C+C + + G C+ +
Sbjct: 1305 PCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 64.3 bits (155), Expect = 2e-09
Identities = 56/221 (25%), Positives = 87/221 (39%), Gaps = 35/221 (15%)
Query: 543 FYNDGKESEVVSFLTTAIES----VDNCPSN-CYGNGDC----ISGTCHCFLGFLGPDCG 593
F N +E + + T ++ + ++ C SN C G+C S C C LG+ G C
Sbjct: 1116 FINKPQEEQFLKISTNSVVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCE 1175
Query: 594 RA-----SCPVLCSGNGQYMKG-RCLCHSGWKGAECDVPTNQCIDVACSNHGTCITGT-- 645
S P + + C C G+ G C+V + C C+N TCI+ T
Sbjct: 1176 LNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG 1235
Query: 646 --CICNPGYKGESCEEV---------DCMDPTCSGRGVCVRGE----CHCSVGWGGTNCE 690
C+C + G+ C + + + TC G C + C C G+ G CE
Sbjct: 1236 YSCLCFGNFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCE 1295
Query: 691 TPRATCL-DQCSGHGTF--LPDTGLCSCDPSWTGHDCSIEI 728
C D C G L + C CD ++ G C +++
Sbjct: 1296 KDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 57.4 bits (137), Expect = 2e-07
Identities = 42/143 (29%), Positives = 56/143 (39%), Gaps = 31/143 (21%)
Query: 563 VDNCPSNCYGNG-DCISGT----CHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSG 617
+DNC S+ NG CIS T C CF F G C ++ P GN K C++G
Sbjct: 1215 IDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE---KTNLTCYNG 1271
Query: 618 WKGAECDVPTNQCIDVACSNHGTCITGTCICNPGYKGESCEEV--DCMDPTCSGRGVCV- 674
E C+C PG+ GE CE+ +C C G+C
Sbjct: 1272 GNCTEFQTELK-----------------CMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 675 ---RGECHCSVGWGGTNCETPRA 694
+ +C C V + G CE A
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDLA 1337
Score = 46.2 bits (108), Expect = 4e-04
Identities = 21/76 (27%), Positives = 34/76 (44%), Gaps = 11/76 (14%)
Query: 764 CAEHGTCRD----GKCECSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHC 819
C G C D C C GW+G+HC + +D C +G C+ + +HC
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELN--IDECFSNPCI-----HGNCSDRVAAYHC 1200
Query: 820 VCQLGWRGAGCDTSME 835
C+ G+ G C+ ++
Sbjct: 1201 TCEPGYTGVNCEVDID 1216
Score = 33.9 bits (76), Expect = 2.3
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 25/114 (21%)
Query: 561 ESVDNCPSN-CYGNGDC--ISG--TCHCFLGFL------GPDCGRASCPVL---CSGNG- 605
E V+ C SN C G C + G TCHC L G DC C NG
Sbjct: 396 EDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGT 455
Query: 606 ---QYMKGR----CLCHSGWKGAECDVPTNQCID---VACSNHGTCITGTCICN 649
+ G+ CLC SG+ G+ C++ T + G+ T +CN
Sbjct: 456 CIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVTTKGSVCN 509
Score = 33.9 bits (76), Expect = 2.3
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 7/47 (14%)
Query: 796 VKEGCPGL--CNGN-----GRCTLDLNGWHCVCQLGWRGAGCDTSME 835
V GC L CN N G C + +HC C LGW G C+ +++
Sbjct: 1133 VVTGCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNID 1179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,896,653
Number of Sequences: 37866
Number of extensions: 5757317
Number of successful extensions: 22805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 284
Number of HSP's that attempted gapping in prelim test: 15304
Number of HSP's gapped (non-prelim): 2466
length of query: 2769
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2649
effective length of database: 13,703,598
effective search space: 36300831102
effective search space used: 36300831102
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.