BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] (1284 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 2595 0.0 gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 459 e-128 gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 427 e-119 gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 427 e-119 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 266 1e-70 gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s... 208 3e-53 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 183 8e-46 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 182 2e-45 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 169 1e-41 gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 159 2e-38 gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 159 2e-38 gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 155 2e-37 gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 155 2e-37 gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 152 3e-36 gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 152 3e-36 gi|48762934 alpha 2 type I collagen [Homo sapiens] 144 5e-34 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 144 5e-34 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 143 9e-34 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 143 9e-34 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 142 2e-33 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 142 2e-33 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 142 2e-33 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 142 2e-33 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 142 2e-33 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 141 4e-33 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 141 4e-33 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 141 4e-33 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 141 4e-33 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 141 5e-33 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 141 5e-33 >gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] Length = 1284 Score = 2595 bits (6727), Expect = 0.0 Identities = 1284/1284 (100%), Positives = 1284/1284 (100%) Query: 1 MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV 60 MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV Sbjct: 1 MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV 60 Query: 61 KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS 120 KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS Sbjct: 61 KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS 120 Query: 121 LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM 180 LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM Sbjct: 121 LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM 180 Query: 181 VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE 240 VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE Sbjct: 181 VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE 240 Query: 241 QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA 300 QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA Sbjct: 241 QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA 300 Query: 301 RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ 360 RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ Sbjct: 301 RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ 360 Query: 361 GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR Sbjct: 361 GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 Query: 421 EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP 480 EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP Sbjct: 421 EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP 480 Query: 481 RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR 540 RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR Sbjct: 481 RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR 540 Query: 541 GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG 600 GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG Sbjct: 541 GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG 600 Query: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG Sbjct: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 Query: 661 DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY 720 DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY Sbjct: 661 DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY 720 Query: 721 YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG Sbjct: 721 YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 Query: 781 LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL 840 LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL Sbjct: 781 LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL 840 Query: 841 PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT 900 PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT Sbjct: 841 PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT 900 Query: 901 IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ 960 IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ Sbjct: 901 IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ 960 Query: 961 EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR 1020 EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR Sbjct: 961 EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR 1020 Query: 1021 SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP 1080 SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP Sbjct: 1021 SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP 1080 Query: 1081 GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE 1140 GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE Sbjct: 1081 GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE 1140 Query: 1141 GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL 1200 GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL Sbjct: 1141 GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL 1200 Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR Sbjct: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260 Query: 1261 GEPGAVGQMGSPGQQGASTQGLWE 1284 GEPGAVGQMGSPGQQGASTQGLWE Sbjct: 1261 GEPGAVGQMGSPGQQGASTQGLWE 1284 >gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] Length = 1796 Score = 459 bits (1180), Expect = e-128 Identities = 293/838 (34%), Positives = 453/838 (54%), Gaps = 63/838 (7%) Query: 20 TLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPK 79 T+ + QV LR V+ D +Q+ W+ G GY + V P +G ++ L K Sbjct: 24 TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83 Query: 80 ATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPS 139 A + GL P + YT+QI A+ +F I+DL+ Sbjct: 84 AIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRK------------------- 124 Query: 140 HTGSPDPEQASEPQVAFTPSQDPRTPAGPQ---FRCLPPVPADMVFLVDGSWSIGHSHFQ 196 DP +P+V + P+ P+ F C P AD+V LVDGSWSIG +F+ Sbjct: 125 -----DP----KPRVKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFR 175 Query: 197 QVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNT 256 V+ FL +++ F++G +K ++GL QYSGD + EW LN+ STK++V+ AVR L YKGGNT Sbjct: 176 LVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNT 235 Query: 257 FTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVK 316 TGLAL ++ + +P AG R +K+ IL+TDGKSQDD+ +R L++ GV +FA+GVK Sbjct: 236 LTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVK 295 Query: 317 NADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDT 376 NAD EL+ +AS P V++V +F + + L+R +C R++ R+ A+A A+ T Sbjct: 296 NADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVE-EQDREIKASAHAI-T 353 Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436 P PT L+ S+VT+ S ++WT AP + KY +V+ +RGG P EVVV+G +ST L NL Sbjct: 354 GP-PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNL 412 Query: 437 ASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHY 496 S TEY ++VF IY EGLRG TT LP L L VT ++ + W GA+ Y Sbjct: 413 MSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGY 472 Query: 497 LVRCSPASPKGEEEEREVQVG--RPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554 L+ +P + +E+E+++G ++ L GL P +Y V+V ++ G E S+ + T Sbjct: 473 LILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETT 532 Query: 555 PTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLG 614 L+PPR+L S+V ++AR+ W+ R + R+ Y +++G + E T+ L Sbjct: 533 LALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEV-DPITTFPLK 591 Query: 615 PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAW-VAAAPS 673 L+ T YT+ + +Y G S LTG TT++ P+ L + E+ D+ ++ W +A Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651 Query: 674 GVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLR 733 G ++++ W P+ GK E+ + + V+ GL TEY+V++LA DG+ S+ V+ Sbjct: 652 G--LHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAV 709 Query: 734 YT--------PST----------VSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775 T P+T V ++ NL + ET SL+V W V + +TY Sbjct: 710 GTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTY 769 Query: 776 APASGLGPEK----SVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 A G PE+ +V VPG+++++ L L T+Y+V V+ IY G +VSA G+T Sbjct: 770 MTAQG-DPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKT 826 Score = 383 bits (984), Expect = e-106 Identities = 212/526 (40%), Positives = 288/526 (54%), Gaps = 71/526 (13%) Query: 823 VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881 V T CP + DG L GF +M F LVEK ++S+ GV+MEP F P + L KDA Sbjct: 1209 VCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKDA 1268 Query: 882 QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941 +++ ++P LP ++TI FL R+LP+TP+E FALW++ ++ PL+GV+LD G K+L Sbjct: 1269 LVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKTL 1328 Query: 942 TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001 TYF+ D Q TF+ E+RKIF+GSFHK+H+ V + V++ +DC++V E+ + + Sbjct: 1329 TYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASAN 1388 Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061 + G LG++ ++RGP +SA FQLQM IVCS +WA+ D+CCELP RD E+CP Sbjct: 1389 ITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDLP 1448 Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP--------------------- 1100 +CSCS GP GPPG PG G G+QG PGP+GP Sbjct: 1449 HSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQGP 1508 Query: 1101 -----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 PG KGEKGD GLPG QG PG G PGR G G +G+ G +G++G PGPP Sbjct: 1509 SGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGPP 1568 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQA----- 1204 GP G G G G +G GP G +GP G+PG KGERGE+G+ QS A + + Q Sbjct: 1569 GPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQLI 1628 Query: 1205 -SHVSKFDSF------------------HENTRPPMPILE-QKLEPGTEPL-------GS 1237 SH++++ + E RP P ++ PGT G+ Sbjct: 1629 QSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGT 1688 Query: 1238 PGTRSKALVPGEWGRGGRHLEG-RGEPGAVG-----QMGSPGQQGA 1277 PG R + GE G G +G RG PG G + GSPG G+ Sbjct: 1689 PGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGS 1734 Score = 135 bits (341), Expect = 2e-31 Identities = 77/208 (37%), Positives = 116/208 (55%), Gaps = 3/208 (1%) Query: 158 PSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKV 216 P+ P P P AD+VF+VDGSWSIG +F ++ FL S + +IG D Sbjct: 1013 PTFPPTIP--PAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGT 1070 Query: 217 QVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGL 276 QV + Q++ D +TE+ LN+ TKE +L A++ + YKGGNT TG A+ +V +G Sbjct: 1071 QVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGT 1130 Query: 277 RPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVH 336 R KV++++TDG+SQDDV+ +R ++ G ++FA+GV +AD +EL + S P V Sbjct: 1131 RRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVF 1190 Query: 337 SVLDFLQLGALAGLLSRLICQRLQGGSP 364 V DF + L +C+ P Sbjct: 1191 FVDDFDAFKKIEDELITFVCETASATCP 1218 Score = 125 bits (315), Expect = 2e-28 Identities = 123/483 (25%), Positives = 208/483 (43%), Gaps = 38/483 (7%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA---SRGGTPREVVVEGPAASTEL 433 LP + L+L VT +S+R+ W P YLI++ G +E+ + EL Sbjct: 443 LPMASDLLLYDVTENSMRVKWDAVPGAS-GYLILYAPLTEGLAGDEKEMKIGETHTDIEL 501 Query: 434 HNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGA 493 L TEY V+V+ ++ + + G TT L PPR L ++ V + LTW P++ Sbjct: 502 SGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQ 561 Query: 494 TH-YLVRCSPASPKGEEEEREVQVGRPEVL-LDGLEPGRDYEVSVQSLRGPEGSEARGIR 551 + Y + + A E EV+V L GL P +Y +++ S+ SE Sbjct: 562 INGYRIVYNNADGT---EINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGV 618 Query: 552 ARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSA 611 T + ++L +V+ D+ RV W L ++ ++ GG + + S Sbjct: 619 FTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSH 678 Query: 612 TLGPLSSSTTYTVRVTCLYPGGGSSTLTGRV-----------TTKKAPSPSQLSMTE--- 657 + L T Y V + + G S + V T P+ S S+ + Sbjct: 679 VIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGI 738 Query: 658 ---LPGD----AVQLAWVAAAPSGVLVYQITW-TPLGEGKAHEIS---VPGNLGTAVLPG 706 + GD ++++ W + S V +++T+ T G+ + I VPG+ +L Sbjct: 739 RNLVVGDETTSSLRVKW-DISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKP 797 Query: 707 LGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG 766 L TEY VT+ Y DG + VS+ T+ S P NL ++ E + L+++W PP Sbjct: 798 LLPDTEYKVTVTPIYTDG---EGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSS 854 Query: 767 RVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSAT 826 V Y + Y P S GP V + + + +L + Y V + A A+G S+A++ Sbjct: 855 PVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGM 914 Query: 827 GQT 829 +T Sbjct: 915 VKT 917 Score = 114 bits (284), Expect = 8e-25 Identities = 73/199 (36%), Positives = 84/199 (42%), Gaps = 56/199 (28%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 RDG + SS PGPPGP G PG+PG G+ G QG GP G PG KGE+G Sbjct: 1546 RDGSPGQRGLPGKDGSSGPPGPPGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERG 1605 Query: 1109 DHG-------------------------------------------LPGLQGHPGHQGIP 1125 + G + G G PG G P Sbjct: 1606 ERGDLQSQAMVRSVARQVCEQLIQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSP 1665 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARG-----TSGERGPPGTVGPTG--- 1177 G G QGP G G G AG+PG PG RG G+ G +G T G RGPPG GP+G Sbjct: 1666 GAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESR 1725 Query: 1178 --LPGPKGERGEKGEPQSL 1194 PGP G G +G P L Sbjct: 1726 PGSPGPPGSPGPRGPPGHL 1744 Score = 100 bits (248), Expect = 1e-20 Identities = 56/125 (44%), Positives = 65/125 (52%), Gaps = 12/125 (9%) Query: 1058 PAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG 1117 P+ S+ PG PG G PG PG G PG GFPG G PG GE+G G+ G +G Sbjct: 1643 PSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKG 1702 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAG--LPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 +PG VG QGP+G G G +G PG PGP G G RG G G PG GP Sbjct: 1703 NPG-------VGTQGPRGPPGPAGPSGESRPGSPGP---PGSPGPRGPPGHLGVPGPQGP 1752 Query: 1176 TGLPG 1180 +G PG Sbjct: 1753 SGQPG 1757 Score = 56.6 bits (135), Expect = 1e-07 Identities = 38/114 (33%), Positives = 43/114 (37%), Gaps = 34/114 (29%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL----------------- 1112 +PG PG QGPPG PG G G G PG RG G+KGEKG+ G+ Sbjct: 1664 SPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGE 1723 Query: 1113 -----------------PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 PG G PG QG G+ G P A P P Sbjct: 1724 SRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGVRAPHPDQP 1777 Score = 56.2 bits (134), Expect = 2e-07 Identities = 57/205 (27%), Positives = 91/205 (44%), Gaps = 14/205 (6%) Query: 366 QGPAAAPALDTLPA--PTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWR-ASRGGTPRE 421 +G + + TLP+ P +L +S+ + +R++W P P P+K Y IV++ S G E Sbjct: 816 EGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDP-PSSPVKGYRIVYKPVSVPGPTLE 874 Query: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481 V + + NL S +Y V +F G + L G+V T L L V Sbjct: 875 TFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTN-LQAKHVEMT 933 Query: 482 TVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV----Q 537 ++ WQ AT Y V + +++E V G GL+P +Y++SV Q Sbjct: 934 SLCAHWQVHRHATAYRVVIESLQDR-QKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQ 992 Query: 538 SLRGPEGS---EARGIRARTPTLAP 559 + GP S + + + R PT P Sbjct: 993 EIEGPSVSIMEKTQSLPTRPPTFPP 1017 Score = 52.8 bits (125), Expect = 2e-06 Identities = 33/95 (34%), Positives = 46/95 (48%), Gaps = 1/95 (1%) Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802 PP+ L + T S V+WT G V Y + Y P G P++ V V G S L +L Sbjct: 355 PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVV-VDGTVSSTVLKNLM 413 Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQTACPALRPD 837 + T+Y++ V AIYA SE + T T + D Sbjct: 414 SLTEYQIAVFAIYAHTASEGLRGTETTLALPMASD 448 >gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo sapiens] Length = 1899 Score = 427 bits (1098), Expect = e-119 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%) Query: 172 CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231 CL AD+V LVDGSWSIG ++F+ V+ F++ ++ F+IGP +VQ+ L QYSGD +TEW Sbjct: 28 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 87 Query: 232 DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291 LN+ K+ +L AV L YKGGNT TG+AL + QN + AG+RP A K+ +L+TDGK Sbjct: 88 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 147 Query: 292 SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351 SQDDV ++ LKD GV +FA+G+KNADE EL+++A+ P D ++V DF L + L Sbjct: 148 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 207 Query: 352 SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411 + +C ++G L AP++LV+S+ T S R+SWTP +Y + + Sbjct: 208 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 255 Query: 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471 GG +E V ST L +L TEY+V+V+ + E E L+G T P+P Sbjct: 256 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 314 Query: 472 ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529 +L + V P T+H+ WQP GAT Y++ P +EV++G ++ L L P Sbjct: 315 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 374 Query: 530 RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 +Y V+VQ++ SE +R T L P+ L DV+H VFWE P VR V Sbjct: 375 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 434 Query: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649 Y + E + E + TS +L L S T YTV V+ ++ G S +T + TT+ P+ Sbjct: 435 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 493 Query: 650 PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709 P+ L +TE+ + + W A S V +Y+ITW P G E + G+ T V L Sbjct: 494 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 552 Query: 710 HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764 +T Y+V+I A Y D + SD + S R P +++P P NL + + T +SL V W P Sbjct: 553 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 612 Query: 765 LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 GRV Y +TY P++G G E++ ++ G ++ V L L+ T Y + VS++Y G ++ Sbjct: 613 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 672 Query: 825 ATGQT 829 G+T Sbjct: 673 GRGKT 677 Score = 362 bits (930), Expect = e-99 Identities = 199/494 (40%), Positives = 281/494 (56%), Gaps = 52/494 (10%) Query: 823 VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881 V T ++CP + DG + PGF ++ A++L EK +AS++GV++E +F + + K+A Sbjct: 1336 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 1395 Query: 882 QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941 + + +D++P LPP +TI+ L RLLPETP + FA+WQ+T D++P +GV+ D K+L Sbjct: 1396 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 1455 Query: 942 TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001 ++F++D R +Q TFD +EV+ +F+GSFHKVH+ V V++Y+DC ++ E+ + E G+ Sbjct: 1456 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 1515 Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061 G+ LG+L K SAAFQ+Q IVCS W DRCC++P+ RD CPAF Sbjct: 1516 ITTDGYEILGKLLKG---ERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 1572 Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 ++C+C+ ++ GPPGP GP G PG G GE+G G GPP G +GD G PG QG PG Sbjct: 1573 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP---GPRGDIGPPGPQGPPGP 1629 Query: 1122 QG-----IPGRVGLQGPK------GMRGLEGTAGLPGPPGP------RGFQGMAGARGTS 1164 QG IPG G QG K G+ G GT GLPGPPGP RGF G GA G Sbjct: 1630 QGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 1689 Query: 1165 GERGPPGTVGPTGL---------------PGPKGERGEKGEPQSLATLYQLVSQASHV-- 1207 G GPPG+ G G+ PGP G +GEKG+ +A+ + + A V Sbjct: 1690 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 1749 Query: 1208 ----SKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGE 1262 + + F++ + P + +PG P G PG A GE G GGR G Sbjct: 1750 QLISGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGF 1803 Query: 1263 PGAVGQMGSPGQQG 1276 PG G G PG++G Sbjct: 1804 PGTPGMQGPPGERG 1817 Score = 178 bits (452), Expect = 3e-44 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436 +PAPT+L +++VTS R +W Y I W E ++ G + NL Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550 Query: 437 ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488 T Y VS+ IY G L L T AP PR L + T ++ + W Sbjct: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 610 Query: 489 PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547 P++G Y + P++ +G E+ + + V+L L+P Y ++V SL P+G Sbjct: 611 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 669 Query: 548 RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606 R R +T L R+L D S V W+ A R ++ Y + GG PG Sbjct: 670 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 729 Query: 607 NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 N A L L T+YTV V +Y GG ++ TGR + Q+ P +++ Sbjct: 730 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 787 Query: 665 LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723 + W AP VL Y++ ++P+ G + I VPGN L L T Y V ++A Y D Sbjct: 788 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 846 Query: 724 G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782 G P R T+ RS P NL + ET +SL V+W G V Y + Y+P G Sbjct: 847 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 902 Query: 783 PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 ++ +VPG R++V L LQ T Y++ V A+Y G ++ G+T Sbjct: 903 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 949 Score = 145 bits (367), Expect = 2e-34 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%) Query: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99 D +KW + Y +++ P G QE+ + GLSP Y + +F Sbjct: 1054 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 1109 Query: 100 GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159 Q P G HT E +EP TP Sbjct: 1110 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 1141 Query: 160 QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218 P P P AD+VFL D SWSIG +F +V F+ + + F EI P +QV Sbjct: 1142 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 1199 Query: 219 GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278 QYS + ++E+ LN+ + K L A++ +RY+GGNT TG ALT + + L +G+R Sbjct: 1200 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 1259 Query: 279 EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338 KV+++VTDG+SQD+V AA V++ G +VF VGV + D EL +AS P + V V Sbjct: 1260 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 1319 Query: 339 LDFLQLGALAGLLSRLICQRLQGGSP 364 DF + L +C+ P Sbjct: 1320 DDFESFEKIEDNLITFVCETATSSCP 1345 Score = 143 bits (360), Expect = 1e-33 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%) Query: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438 P +L + TS+S+ + W PA KY I ++ S G G + + G S L L Sbjct: 592 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 651 Query: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497 T Y ++V +Y G G + G T PL R L + + T+++ W + G Y Sbjct: 652 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 711 Query: 498 VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557 + +PA+ G EE + +L L+P Y V+V + RT Sbjct: 712 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 770 Query: 558 APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616 R++ + + ++ V W+ AP PV RV Y +G ++ PGN L L Sbjct: 771 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 830 Query: 617 SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676 T Y+V + LY G + + T P L + +++ +AW A V Sbjct: 831 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 889 Query: 677 VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735 Y+I ++P +G+ +VPG +L L T Y +T++A Y DG D L Sbjct: 890 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 946 Query: 736 PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795 TV PP N+ ++ E +VSW P VL Y + Y P P + + G + Sbjct: 947 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 1004 Query: 796 VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 TL +L +T Y V V A Y +G S ++ G T Sbjct: 1005 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 1038 Score = 113 bits (283), Expect = 1e-24 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%) Query: 389 TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447 T +S+ + W PAP L+Y +V+ G P E +VV G L L T Y V++ Sbjct: 782 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 841 Query: 448 PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506 +Y G G T P PR L + T ++ + W + G Y + SP Sbjct: 842 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 901 Query: 507 GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565 +E V R V+L L+P Y+++V ++ +G G RT L PP+++ Sbjct: 902 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 960 Query: 566 SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625 SD + RV W+ +P PV ++ Y G + G TS TL L+ STTY V Sbjct: 961 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 1019 Query: 626 VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685 V Y G S LT + TT + + L ++ D + W + Y++ +P Sbjct: 1020 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 1076 Query: 686 GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717 + EI+V G+ + GL T+Y VT+ Sbjct: 1077 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 1108 Score = 106 bits (264), Expect = 2e-22 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 S PGPPGP GPP G+ G +G PGP G PG G PG+QG PG +G+PG Sbjct: 1773 SRNQPGPPGPPGPP------GSAGARGEPGPGGRPGFP------GTPGMQGPPGERGLPG 1820 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G +G G G GLPGPPGP+G + G G++G RGPP GP G PG G RG Sbjct: 1821 EKGERG----TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 1872 Query: 1187 EKGEP 1191 G P Sbjct: 1873 PPGPP 1877 Score = 53.5 bits (127), Expect = 1e-06 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%) Query: 363 SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 SP QG TLP P +L + T++S+ ++W A +Y I++ + G Sbjct: 852 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 904 Query: 421 E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479 E V G + L L T Y ++V +YE G G L G T L PP+ + ++ Sbjct: 905 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 964 Query: 480 PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538 ++W PS L P G E E VG L L P Y+V+V + Sbjct: 965 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 1022 Query: 539 LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598 + G T L + D V W R R+ ++G Sbjct: 1023 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 1080 Query: 599 SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652 + G+ TS LS T Y V V P G ++ T K +P++ Sbjct: 1081 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 1136 Score = 32.7 bits (73), Expect = 2.3 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%) Query: 42 LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101 L ++W +EG+ Y + P AG E+ V + T A + L P YT+ + + Sbjct: 696 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 755 Query: 102 GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156 G + ++S R+ R L PTP+ P P + +V + Sbjct: 756 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 804 Query: 157 TPSQDPR 163 +P R Sbjct: 805 SPVDGTR 811 >gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo sapiens] Length = 3063 Score = 427 bits (1098), Expect = e-119 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%) Query: 172 CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231 CL AD+V LVDGSWSIG ++F+ V+ F++ ++ F+IGP +VQ+ L QYSGD +TEW Sbjct: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 1251 Query: 232 DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291 LN+ K+ +L AV L YKGGNT TG+AL + QN + AG+RP A K+ +L+TDGK Sbjct: 1252 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 1311 Query: 292 SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351 SQDDV ++ LKD GV +FA+G+KNADE EL+++A+ P D ++V DF L + L Sbjct: 1312 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 1371 Query: 352 SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411 + +C ++G L AP++LV+S+ T S R+SWTP +Y + + Sbjct: 1372 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 1419 Query: 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471 GG +E V ST L +L TEY+V+V+ + E E L+G T P+P Sbjct: 1420 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 1478 Query: 472 ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529 +L + V P T+H+ WQP GAT Y++ P +EV++G ++ L L P Sbjct: 1479 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 1538 Query: 530 RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 +Y V+VQ++ SE +R T L P+ L DV+H VFWE P VR V Sbjct: 1539 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 1598 Query: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649 Y + E + E + TS +L L S T YTV V+ ++ G S +T + TT+ P+ Sbjct: 1599 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 1657 Query: 650 PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709 P+ L +TE+ + + W A S V +Y+ITW P G E + G+ T V L Sbjct: 1658 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 1716 Query: 710 HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764 +T Y+V+I A Y D + SD + S R P +++P P NL + + T +SL V W P Sbjct: 1717 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 1776 Query: 765 LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 GRV Y +TY P++G G E++ ++ G ++ V L L+ T Y + VS++Y G ++ Sbjct: 1777 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 1836 Query: 825 ATGQT 829 G+T Sbjct: 1837 GRGKT 1841 Score = 362 bits (930), Expect = e-99 Identities = 199/494 (40%), Positives = 281/494 (56%), Gaps = 52/494 (10%) Query: 823 VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881 V T ++CP + DG + PGF ++ A++L EK +AS++GV++E +F + + K+A Sbjct: 2500 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 2559 Query: 882 QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941 + + +D++P LPP +TI+ L RLLPETP + FA+WQ+T D++P +GV+ D K+L Sbjct: 2560 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 2619 Query: 942 TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001 ++F++D R +Q TFD +EV+ +F+GSFHKVH+ V V++Y+DC ++ E+ + E G+ Sbjct: 2620 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 2679 Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061 G+ LG+L K SAAFQ+Q IVCS W DRCC++P+ RD CPAF Sbjct: 2680 ITTDGYEILGKLLKG---ERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 2736 Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 ++C+C+ ++ GPPGP GP G PG G GE+G G GPP G +GD G PG QG PG Sbjct: 2737 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP---GPRGDIGPPGPQGPPGP 2793 Query: 1122 QG-----IPGRVGLQGPK------GMRGLEGTAGLPGPPGP------RGFQGMAGARGTS 1164 QG IPG G QG K G+ G GT GLPGPPGP RGF G GA G Sbjct: 2794 QGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853 Query: 1165 GERGPPGTVGPTGL---------------PGPKGERGEKGEPQSLATLYQLVSQASHV-- 1207 G GPPG+ G G+ PGP G +GEKG+ +A+ + + A V Sbjct: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913 Query: 1208 ----SKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGE 1262 + + F++ + P + +PG P G PG A GE G GGR G Sbjct: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGF 2967 Query: 1263 PGAVGQMGSPGQQG 1276 PG G G PG++G Sbjct: 2968 PGTPGMQGPPGERG 2981 Score = 302 bits (774), Expect = 1e-81 Identities = 224/695 (32%), Positives = 336/695 (48%), Gaps = 24/695 (3%) Query: 176 VPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNS 235 + AD+VFLVDGS+SIG ++F +V+ FL ++ FEI P++VQ+ L QYS D TE+ L Sbjct: 437 IKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKK 496 Query: 236 LSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDD 295 + E ++ A+ Y+GG+T TG A+T+V + P+ G R KV+IL+TDGKS D Sbjct: 497 FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556 Query: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355 A L++ V +FAVGVK+A +EL +ASPP + V +V DF ++ L++ I Sbjct: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616 Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASR 415 C R++ Q AA +P P L S+VTS + +W+PA + Y I ++ + Sbjct: 617 CLRIE-----QELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAA 670 Query: 416 GGTPREVVVEGPAASTE--LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLP-PPRA 472 G EV V PA+ST L +L T YLV+V YE G L G TT + PR Sbjct: 671 GDD--EVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 Query: 473 LTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRD 531 L + T + +TW + G Y + P + GE E + L+ L P Sbjct: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTK 787 Query: 532 YEVSV--QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 YEVSV + GP G+ G A PR L SD + ++ W GAP V+ V Sbjct: 788 YEVSVIPEYFSGP-GTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLV 846 Query: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT-KKAP 648 TY GG + + G+ T+ L L T Y + VT LY G L G TT ++ Sbjct: 847 TYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERG 906 Query: 649 SPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGL 707 SP L ++ ++ W +AP V Y+++W L + E ++P + ++ L Sbjct: 907 SPQDLVTKDITDTSIGAYW-TSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENL 965 Query: 708 GRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGR 767 T+Y +++ A Y G +P L +T L + ET ++++V+W P G+ Sbjct: 966 QPETKYRISVFATYSSG-EGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022 Query: 768 VLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATG 827 V++Y + Y P G G + VP + L LQ T Y + V IY G + +G Sbjct: 1023 VVNYRVVYRP-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081 Query: 828 QTACPALRPDGSLPGFDLMVAFSLV-EKAYASIRG 861 TA P M +F + E A ++G Sbjct: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKG 1116 Score = 199 bits (506), Expect = 1e-50 Identities = 125/457 (27%), Positives = 227/457 (49%), Gaps = 58/457 (12%) Query: 17 LGATLGREQVQAS----GLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVI 72 LGA L ++A L ++ E+ + M W + +GY + V P +E Sbjct: 12 LGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFT 71 Query: 73 LTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSG 132 L+ T + + L P Y + I D S+ Q + +G Sbjct: 72 LSASTTETLLSELVPETEYVVTITSY----------------DEVEESVPVIGQLTIQTG 115 Query: 133 AP-EPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIG 191 + +P G + + +C D+VFLVDGSWS+G Sbjct: 116 SSTKPVEKKPGKTEIQ-----------------------KCSVSAWTDLVFLVDGSWSVG 152 Query: 192 HSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRY 251 ++F+ + DF+A++++ F+IG +K +VG+ QYS D +TE++LN ++++LAA++++ Y Sbjct: 153 RNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPY 212 Query: 252 KGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVF 311 KGGNT TG A+ +++ +AG R KV I++TDGKSQD+V AR L+++GV VF Sbjct: 213 KGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVF 272 Query: 312 AVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAA 371 ++G+K AD EL+ +AS P +++ V + A+ + + +I Q G + G + Sbjct: 273 SLGIKAADAKELKQIASTP---SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVS 329 Query: 372 PALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAAST 431 + + P++L+ +V+S ++L+W P+P Y ++ G+ + + GP +T Sbjct: 330 -GEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTT 388 Query: 432 -ELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPL 467 + +L++ TEY +SV ++G+ ++ P+ Sbjct: 389 LSVRDLSADTEYQISV---------SAMKGMTSSEPI 416 Score = 178 bits (452), Expect = 3e-44 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436 +PAPT+L +++VTS R +W Y I W E ++ G + NL Sbjct: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 1714 Query: 437 ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488 T Y VS+ IY G L L T AP PR L + T ++ + W Sbjct: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774 Query: 489 PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547 P++G Y + P++ +G E+ + + V+L L+P Y ++V SL P+G Sbjct: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 1833 Query: 548 RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606 R R +T L R+L D S V W+ A R ++ Y + GG PG Sbjct: 1834 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 1893 Query: 607 NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 N A L L T+YTV V +Y GG ++ TGR + Q+ P +++ Sbjct: 1894 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 1951 Query: 665 LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723 + W AP VL Y++ ++P+ G + I VPGN L L T Y V ++A Y D Sbjct: 1952 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 2010 Query: 724 G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782 G P R T+ RS P NL + ET +SL V+W G V Y + Y+P G Sbjct: 2011 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066 Query: 783 PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 ++ +VPG R++V L LQ T Y++ V A+Y G ++ G+T Sbjct: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 2113 Score = 177 bits (448), Expect = 8e-44 Identities = 136/448 (30%), Positives = 205/448 (45%), Gaps = 12/448 (2%) Query: 379 APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLAS 438 AP +L ++ T+ S +++WT AP L+Y I++R GG REV L NL Sbjct: 725 APRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIP 784 Query: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPP-PRALTLAAVTPRTVHLTWQPSAGAT-HY 496 T+Y VSV P Y G G L G T + PR L ++ T T+ L+W + G Y Sbjct: 785 DTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQY 844 Query: 497 LVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR-GIRARTP 555 LV +P + GE +E V+ +L GL+ G Y +SV +L +A G Sbjct: 845 LVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLE 903 Query: 556 TLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSS-EGGHSGQTEAPGNATSATLG 614 P+ L D++ + +W AP VR RV++ S + +G+ P +A + Sbjct: 904 ERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIE 963 Query: 615 PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSG 674 L T Y + V Y G LTG TT+ + L + E + +++ W AP Sbjct: 964 NLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK 1022 Query: 675 VLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRY 734 V+ Y++ + P G GK VP + + VL L T YD+T+L Y+ G LR Sbjct: 1023 VVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK----LRQ 1078 Query: 735 -TPSTVSR-SPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGA 792 + +T SR P NL + T S +V+W P G V Y +T+ P + V Sbjct: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPY 1138 Query: 793 RSHVTLPDLQAATKYRVLVSAIYAAGRS 820 + V L +L+A T Y+V V ++ G S Sbjct: 1139 DNTVVLEELRAGTTYKVNVFGMFDGGES 1166 Score = 145 bits (367), Expect = 2e-34 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%) Query: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99 D +KW + Y +++ P G QE+ + GLSP Y + +F Sbjct: 2218 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 2273 Query: 100 GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159 Q P G HT E +EP TP Sbjct: 2274 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 2305 Query: 160 QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218 P P P AD+VFL D SWSIG +F +V F+ + + F EI P +QV Sbjct: 2306 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 2363 Query: 219 GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278 QYS + ++E+ LN+ + K L A++ +RY+GGNT TG ALT + + L +G+R Sbjct: 2364 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 2423 Query: 279 EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338 KV+++VTDG+SQD+V AA V++ G +VF VGV + D EL +AS P + V V Sbjct: 2424 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 2483 Query: 339 LDFLQLGALAGLLSRLICQRLQGGSP 364 DF + L +C+ P Sbjct: 2484 DDFESFEKIEDNLITFVCETATSSCP 2509 Score = 143 bits (360), Expect = 1e-33 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%) Query: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438 P +L + TS+S+ + W PA KY I ++ S G G + + G S L L Sbjct: 1756 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 1815 Query: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497 T Y ++V +Y G G + G T PL R L + + T+++ W + G Y Sbjct: 1816 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 1875 Query: 498 VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557 + +PA+ G EE + +L L+P Y V+V + RT Sbjct: 1876 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 1934 Query: 558 APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616 R++ + + ++ V W+ AP PV RV Y +G ++ PGN L L Sbjct: 1935 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 1994 Query: 617 SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676 T Y+V + LY G + + T P L + +++ +AW A V Sbjct: 1995 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 2053 Query: 677 VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735 Y+I ++P +G+ +VPG +L L T Y +T++A Y DG D L Sbjct: 2054 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 2110 Query: 736 PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795 TV PP N+ ++ E +VSW P VL Y + Y P P + + G + Sbjct: 2111 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 2168 Query: 796 VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 TL +L +T Y V V A Y +G S ++ G T Sbjct: 2169 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202 Score = 113 bits (283), Expect = 1e-24 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%) Query: 389 TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447 T +S+ + W PAP L+Y +V+ G P E +VV G L L T Y V++ Sbjct: 1946 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 2005 Query: 448 PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506 +Y G G T P PR L + T ++ + W + G Y + SP Sbjct: 2006 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 2065 Query: 507 GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565 +E V R V+L L+P Y+++V ++ +G G RT L PP+++ Sbjct: 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 2124 Query: 566 SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625 SD + RV W+ +P PV ++ Y G + G TS TL L+ STTY V Sbjct: 2125 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 2183 Query: 626 VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685 V Y G S LT + TT + + L ++ D + W + Y++ +P Sbjct: 2184 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 2240 Query: 686 GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717 + EI+V G+ + GL T+Y VT+ Sbjct: 2241 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 2272 Score = 106 bits (264), Expect = 2e-22 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 S PGPPGP GPP G+ G +G PGP G PG G PG+QG PG +G+PG Sbjct: 2937 SRNQPGPPGPPGPP------GSAGARGEPGPGGRPGFP------GTPGMQGPPGERGLPG 2984 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G +G G G GLPGPPGP+G + G G++G RGPP GP G PG G RG Sbjct: 2985 EKGERG----TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 3036 Query: 1187 EKGEP 1191 G P Sbjct: 3037 PPGPP 3041 Score = 103 bits (256), Expect = 1e-21 Identities = 80/275 (29%), Positives = 124/275 (45%), Gaps = 5/275 (1%) Query: 374 LDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR-EVVVEGPAASTE 432 L+ +P LV +T +SI WT AP Y + W++ E + A T Sbjct: 902 LEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM 961 Query: 433 LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG 492 + NL T+Y +SVF Y G GE L G TT + L + T T+ +TW+P+ G Sbjct: 962 IENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPG 1021 Query: 493 -ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGI 550 +Y V P +G++ +V +L L+P Y+++V + + EG +G Sbjct: 1022 KVVNYRVVYRPHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080 Query: 551 RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTY-VSSEGGHSGQTEAPGNAT 609 PR+L SD + + RV WE AP V+ +VT+ + + G+ Sbjct: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140 Query: 610 SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT 644 + L L + TTY V V ++ GG SS L G+ T Sbjct: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMT 1175 Score = 53.5 bits (127), Expect = 1e-06 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%) Query: 363 SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 SP QG TLP P +L + T++S+ ++W A +Y I++ + G Sbjct: 2016 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 2068 Query: 421 E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479 E V G + L L T Y ++V +YE G G L G T L PP+ + ++ Sbjct: 2069 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 2128 Query: 480 PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538 ++W PS L P G E E VG L L P Y+V+V + Sbjct: 2129 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 2186 Query: 539 LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598 + G T L + D V W R R+ ++G Sbjct: 2187 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 2244 Query: 599 SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652 + G+ TS LS T Y V V P G ++ T K +P++ Sbjct: 2245 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 2300 Score = 42.0 bits (97), Expect = 0.004 Identities = 24/87 (27%), Positives = 44/87 (50%) Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802 PPSNL + ++++W P V Y + P + + ++SV + +++ DL Sbjct: 336 PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLS 395 Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQT 829 A T+Y++ VSA+ SE +S +T Sbjct: 396 ADTEYQISVSAMKGMTSSEPISIMEKT 422 Score = 37.4 bits (85), Expect = 0.093 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%) Query: 634 GSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEI 693 G++ L + + P PS L+ + + V ++W A ++ Y+IT P +G E Sbjct: 13 GAALLLSSIEAEVDP-PSDLNFKIIDENTVHMSW-AKPVDPIVGYRITVDPTTDGPTKEF 70 Query: 694 SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPP 744 ++ + +L L TEY VTI + Y + S PV + T T S + P Sbjct: 71 TLSASTTETLLSELVPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKP 120 Score = 37.4 bits (85), Expect = 0.093 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 2/104 (1%) Query: 453 GVGEGLRGLVTTAPL-PPPRALTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEE 510 GV E L LV+ + PP L V+ + V L W PS T Y V +P + + Sbjct: 319 GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQH 378 Query: 511 EREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554 V + + L +Y++SV +++G SE I +T Sbjct: 379 ALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 Score = 37.0 bits (84), Expect = 0.12 Identities = 21/71 (29%), Positives = 31/71 (43%) Query: 32 LRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGY 91 LR++ +++ W + G YLV P+AG QEV + T + GL Y Sbjct: 820 LRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQY 879 Query: 92 TLQIFELTGSG 102 L + L SG Sbjct: 880 ALSVTALYASG 890 Score = 36.2 bits (82), Expect = 0.21 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%) Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802 PPS+L +++ +SW P+ ++ Y +T P + GP K ++ + + L +L Sbjct: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD-GPTKEFTLSASTTETLLSELV 85 Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQ 828 T+Y V +++ E+V GQ Sbjct: 86 PETEYVVTITSYDEV--EESVPVIGQ 109 Score = 34.3 bits (77), Expect = 0.79 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFE-- 97 D ++ W ++ G L Y + +P+AG +EV + T+ L P Y + + Sbjct: 737 DSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 Query: 98 LTGSGRFLL--ARREFV---IEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEP 152 +G G L A E V DL+ S S+ + SGAP + + P E Sbjct: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET 856 Query: 153 Q 153 Q Sbjct: 857 Q 857 Score = 33.9 bits (76), Expect = 1.0 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 465 APLPPPRALTLAAVTPRTVHLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLL 523 A + PP L + TVH++W +P Y + P + G +E + E LL Sbjct: 23 AEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLL 81 Query: 524 DGLEPGRDYEVSVQS 538 L P +Y V++ S Sbjct: 82 SELVPETEYVVTITS 96 Score = 32.7 bits (73), Expect = 2.3 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%) Query: 42 LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101 L ++W +EG+ Y + P AG E+ V + T A + L P YT+ + + Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 1919 Query: 102 GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156 G + ++S R+ R L PTP+ P P + +V + Sbjct: 1920 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 1968 Query: 157 TPSQDPR 163 +P R Sbjct: 1969 SPVDGTR 1975 Score = 31.6 bits (70), Expect = 5.1 Identities = 27/126 (21%), Positives = 48/126 (38%), Gaps = 3/126 (2%) Query: 559 PPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSS 618 PP L F + + + W P+ R+T + G + + + T L L Sbjct: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVP 86 Query: 619 STTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDA-VQLAWVAAAPSGVLV 677 T Y V +T S + G++T + S + + PG +Q V+A V + Sbjct: 87 ETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVE--KKPGKTEIQKCSVSAWTDLVFL 144 Query: 678 YQITWT 683 +W+ Sbjct: 145 VDGSWS 150 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 266 bits (679), Expect = 1e-70 Identities = 229/687 (33%), Positives = 325/687 (47%), Gaps = 45/687 (6%) Query: 159 SQDPRTPAGPQFR--CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFE--IGPD 214 ++ PR A + R C AD+VFL+DGS SIG S+F++V+ FL ++ PF Sbjct: 16 AEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQ 75 Query: 215 KVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAA 274 V+ QYS D +TE+ L++L + V+ A+R L YKGGNT TG A+ HV P Sbjct: 76 GVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL 135 Query: 275 GLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDIT 334 RP KV IL+TDGKSQD V TAA+ LK GV +FAVG+KNAD EL+ +AS P Sbjct: 136 A-RPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDF 194 Query: 335 VHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIR 394 V DF L L L+SR +C G P P D+ AP LVLS+ +S S+R Sbjct: 195 FFFVNDFSILRTLLPLVSRRVCTTAGG-----VPVTRPPDDSTSAPRDLVLSEPSSQSLR 249 Query: 395 LSWTPAPRHPLKYLIVWRASRG-GTP-----REVVVEGPAASTELHNLASRTEYLVSVFP 448 + WT A Y + + G G P +EV V S L L TEY V+V Sbjct: 250 VQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIA 309 Query: 449 IYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGE 508 +Y +GE + G T L P LT+ T ++ + W+ GAT Y V S G Sbjct: 310 LYANSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGATGYRVTWRVLS-GGP 367 Query: 509 EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP----PRHLG 564 +++E+ G+ VLL LEPG DYEV+V +L G A + ART P LG Sbjct: 368 TQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVILG 427 Query: 565 FSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEAPGNATSATLGPLSSSTTYT 623 + + + W P R R+ + G Q P + T L L T Y Sbjct: 428 PTSI-----LLSWNLVPE-ARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYR 481 Query: 624 VRVTCLYPGGGSSTLTGRVTT--KKAPSP-SQLSMTELPGDAVQLAWVAAAPSGVLVYQI 680 + + L G +T V T + SP + L TELPG V+++W + G Y+I Sbjct: 482 LTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW--SPVPGATQYRI 539 Query: 681 TWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYY--RDGARSDPVSLRYTPST 738 +G + +PG+ L + Y V + A R+G+ S +++R P T Sbjct: 540 I-VRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSAS-VLTVRREPET 597 Query: 739 VSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTL 798 P + ++ T ++V+W P G + ++G GPE S ++P + + Sbjct: 598 PLAVPGLRVVVSDAT--RVRVAWGPVPGA---SGFRISWSTGSGPESSQTLPPDSTATDI 652 Query: 799 PDLQAATKYRVLVSAIYAAGRSEAVSA 825 LQ T Y+V VS + GR E +A Sbjct: 653 TGLQPGTTYQVAVSVL--RGREEGPAA 677 Score = 144 bits (362), Expect = 7e-34 Identities = 140/512 (27%), Positives = 218/512 (42%), Gaps = 28/512 (5%) Query: 330 PRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVT 389 P D+T + LD LQ G L + + + +P P L P T L +++ Sbjct: 463 PSDVTRYQ-LDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPV-TDLQATELP 520 Query: 390 SSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPI 449 +R+SW+P P +Y I+ R+++G R +V+ G + +L ++ + Y V V Sbjct: 521 GQRVRVSWSPVPG-ATQYRIIVRSTQG-VERTLVLPGSQTAFDLDDVQAGLSYTVRVSA- 577 Query: 450 YEGGVGEGLRGLVTT-----APLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPAS 504 G EG ++T PL P + + R V + W P GA+ + + S S Sbjct: 578 -RVGPREGSASVLTVRREPETPLAVPGLRVVVSDATR-VRVAWGPVPGASGFRISWSTGS 635 Query: 505 PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLG 564 G E + + + GL+PG Y+V+V LRG E A I ART L P R + Sbjct: 636 --GPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVH 693 Query: 565 FSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTV 624 + S + + W P RV++ S+ G Q G AT A L L T YTV Sbjct: 694 VTQASSSSVTITWTRVPGATG-YRVSWHSAHGPEKSQL-VSGEATVAELDGLEPDTEYTV 751 Query: 625 RVTCLYPG--GGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITW 682 V G G +++ R + S+L + D +++ WV +G Y++ W Sbjct: 752 HVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGV--TGATAYRLAW 809 Query: 683 TPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRS 742 G +PGN +A + GL Y V + A D PVS+ T T + Sbjct: 810 GRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGD-REGTPVSIVVT--TPPEA 866 Query: 743 PPS--NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPD 800 PP+ L + SL++ W P+ R + L + P G E+S + S L Sbjct: 867 PPALGTLHVVQRGEHSLRLRW-EPVPRAQGFLLHWQPEG--GQEQSRVLGPELSSYHLDG 923 Query: 801 LQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832 L+ AT+YRV +S + AG + T +T P Sbjct: 924 LEPATQYRVRLSVLGPAGEGPSAEVTARTESP 955 Score = 144 bits (362), Expect = 7e-34 Identities = 102/276 (36%), Positives = 131/276 (47%), Gaps = 48/276 (17%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL------PGRNGTP---GEQGFPGPRG 1099 PA G+ P + S PG GP GP G PGR+G P GEQG PGP G Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGIP---------------GRVGLQGPKGMRGL----- 1139 PPG+ G+ G+ G PGL G G G P GR G GPKG RG Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884 Query: 1140 -EGTAGLPGPPGP--RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLAT 1196 +G GLPGP GP +GF G+ G G G+RG G+ G GLPG +G RGE G ++ Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDR 1944 Query: 1197 LYQLVS-QASHVSKF-DSFHENTRPPMPILEQKL----------EPGTE-PLGSPGTR-- 1241 L + +AS + + +++ E++ +P+ E++ PG E P+G PG R Sbjct: 1945 LLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGL 2004 Query: 1242 -SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G G L RG PG G G PG+ G Sbjct: 2005 KGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG 2040 Score = 134 bits (337), Expect = 6e-31 Identities = 97/258 (37%), Positives = 116/258 (44%), Gaps = 52/258 (20%) Query: 1070 TPGPPGP-----------------QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL 1112 TPGPPGP QGPPGL G G PG G GP+G GV G KGD G Sbjct: 2083 TPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142 Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---------------PGPRGFQGM 1157 PG +G G+ G+PG G+ GP+G GL+G G PGP GP G QG Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202 Query: 1158 AGARGTSGERGPP--GTVGPTGL------PGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 +G +G GE GPP G GPTG PGP G G +G P + + + Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262 Query: 1210 FDSFHENTR-----PPMPILEQKLEPGTEPLGSPGTRSKALV--PGEWGR----GGRHLE 1258 S + R P P L + P EP G G +A+V PG G GG + Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEP-GPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321 Query: 1259 GRGEPGAVGQMGSPGQQG 1276 GEPGA G G PG +G Sbjct: 2322 LVGEPGAKGDRGLPGPRG 2339 Score = 132 bits (331), Expect = 3e-30 Identities = 94/235 (40%), Positives = 107/235 (45%), Gaps = 24/235 (10%) Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 E CP + PG G +G G PG G PG G PGP+GPPG KG+ G PG Sbjct: 1245 EPCPVYCP--KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPG 1302 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV- 1173 G PG PGR G G G GL+G+ PG PGPRG G G RG GE G PG V Sbjct: 1303 ADGRPGS---PGRAGNPGTPGAPGLKGS---PGLPGPRGDPGERGPRGPKGEPGAPGQVI 1356 Query: 1174 ---GPTGLPGPKGERGEKGEPQSLATLYQLVSQA-----SHVSKFDSFHENTRPPMPILE 1225 GP GLPG KG+ G G P L + K D R P E Sbjct: 1357 GGEGP-GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE 1415 Query: 1226 QKLEPGTEPL----GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 + PG L GSPG + PG+ G G + G PG GQ GSPG+QG Sbjct: 1416 GGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED--GAPGLPGQPGSPGEQG 1468 Score = 130 bits (327), Expect = 8e-30 Identities = 93/218 (42%), Positives = 105/218 (48%), Gaps = 27/218 (12%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVK---GEKGDHGLPGLQGHPGHQGIP 1125 GP GP+G PGLPG G G +GF PGP+G PGV+ GEKGD G PGL G G G P Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------GTSGERGPPGTVGPTGLP 1179 G G GP G G G G G PG RG QG+ G G GE G PG G G P Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847 Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE-PLGSP 1238 G GE G KGE S AS D + R IL + PG P+G P Sbjct: 1848 GDPGEDGRKGEKGD--------SGASGREGRDG-PKGERGAPGILGPQGPPGLPGPVGPP 1898 Query: 1239 GTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G VPG G G RGE G+ G+ G PG++G Sbjct: 1899 GQGFPG-VPGGTGPKG----DRGETGSKGEQGLPGERG 1931 Score = 129 bits (323), Expect = 2e-29 Identities = 104/303 (34%), Positives = 124/303 (40%), Gaps = 35/303 (11%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P GE G A G +G L A+G + + ++ + A DR P G Sbjct: 2288 PKGEPGPTGAPGQAVVG-LPGAKGEKGAPGGLAGDLV----GEPGAKGDRGLPGPRGEKG 2342 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF--PGPRGPPGVKGEKGDHGL 1112 E A PG PG G G PG G G+ G PG GPPG G KGD GL Sbjct: 2343 EAGRA---------GEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393 Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 PGL G PG G PG+ G +G G G G GL GPPG G G G G G GPPG Sbjct: 2394 PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453 Query: 1173 VG--------PTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 G GLPGP+GERGE G Q + + + Sbjct: 2454 SGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSA 2513 Query: 1225 EQKLEPGTEP--LGSPGTRSKALVPGEWGRGGRHLEG-------RGEPGAVGQMGSPGQQ 1275 K + G LG PG R GE RG R L+G G+PG G G PG + Sbjct: 2514 GLKGDKGDSAVILGPPGPRGAKGDMGE--RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDK 2571 Query: 1276 GAS 1278 G++ Sbjct: 2572 GSA 2574 Score = 125 bits (315), Expect = 2e-28 Identities = 107/295 (36%), Positives = 133/295 (45%), Gaps = 52/295 (17%) Query: 997 GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056 GE GS P + RL + G ++S+ + +IV +TW DE LP Sbjct: 1934 GEPGSVP-----NVDRLLETAGIKASA------LREIV--ETW-DESSGSFLPV------ 1973 Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVK-GEKGDHGLPGL 1115 P S GPPG +GP G PG G G++G PGP+GPPG+ GE+G G GL Sbjct: 1974 -PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGL 2032 Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP---PGT 1172 G PG GIPG + G G G G PG RG +G G RG G GP PGT Sbjct: 2033 AGEPGKPGIPG---------LPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGT 2083 Query: 1173 VGPTGLPGPK--------GERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 GP G PGPK G GE+G P ++ S D + R I Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKG------AKGEPGSNGDQGPKGDRGVPGIK 2137 Query: 1225 EQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQGA 1277 + EPG G+PG + + G G+ G L+G RG PG VG G PG GA Sbjct: 2138 GDRGEPGPRGQDGNPGLPGERGMAGPEGKPG--LQGPRGPPGPVGGHGDPGPPGA 2190 Score = 124 bits (312), Expect = 4e-28 Identities = 91/228 (39%), Positives = 103/228 (45%), Gaps = 53/228 (23%) Query: 1071 PGPPGPQGP-----------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 PG PGPQGP PGLPG+ G+PGEQG PRGPPG G KGD G P Sbjct: 1429 PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG---PRGPPGAIGPKGDRGFP 1485 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG-- 1171 G G G + G G GP G RGL G AG PG GP G G G +G GE G PG Sbjct: 1486 GPLGEAGEK---GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542 Query: 1172 -TVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228 VGP + GPKGE+G+ G P+ + + R P P L Sbjct: 1543 AVVGP-AVAGPKGEKGDVGPAGPRGATGV-----------------QGERGP-PGLVLPG 1583 Query: 1229 EPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 +PG P G PG R + G G G G PG G G PG G Sbjct: 1584 DPG--PKGDPGDRGPIGLTGRAGPPG----DSGPPGEKGDPGRPGPPG 1625 Score = 124 bits (312), Expect = 4e-28 Identities = 89/228 (39%), Positives = 104/228 (45%), Gaps = 29/228 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPG +G GLPG G PG GFPG GP G G+ G G GL G PG +GIPG +G Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP 2441 Query: 1131 QGPKGMRGLEGTAGLPGP--------PGPRGFQGMAGARGTSGE---------RGPPGTV 1173 GP G G G +GL G PGPRG +G G RG G GPPG+ Sbjct: 2442 PGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSR 2501 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G G G G KG+ A + L +K D R P + K G Sbjct: 2502 GERGEKGDVGSAGLKGDKGDSAVI--LGPPGPRGAKGDM---GERGPRGLDGDKGPRGDN 2556 Query: 1234 PLGSPGTRSKALVPGEWGRGG----RHLEG-RGEPGAVGQMGSPGQQG 1276 G PG + PG+ G G R L G +G+PGA G G PG G Sbjct: 2557 --GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602 Score = 122 bits (306), Expect = 2e-27 Identities = 83/220 (37%), Positives = 101/220 (45%), Gaps = 30/220 (13%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 S+ PG G GP G PG G PG+ G PG G PG++GEKGD G G +G G +G+ G Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKG 2632 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP------TGLPG 1180 GL G KG +G G G PG G +G G G G SG G G +GP G PG Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692 Query: 1181 PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240 PKG++GEKGE + F N P PG P GS G Sbjct: 2693 PKGDQGEKGE-----------RGTPGIGGFPGPSGNDGSAGP-------PG--PPGSVGP 2732 Query: 1241 RSKALVPGEWGR----GGRHLEGRGEPGAVGQMGSPGQQG 1276 R + G+ G G R + G PGA G+ G G+ G Sbjct: 2733 RGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPG 2772 Score = 122 bits (305), Expect = 3e-27 Identities = 95/253 (37%), Positives = 113/253 (44%), Gaps = 53/253 (20%) Query: 1071 PGPPGPQGP------------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL 1112 PGPPGP GP PGLPG+ G G +G PG RGP G KG++GD G Sbjct: 1621 PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE 1680 Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGM-------------RGLEGTAGLPGPPGPRGFQGMAG 1159 G G PG G G G GP G +G G G GP GP+G G+ G Sbjct: 1681 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG 1740 Query: 1160 A---RGTSGERGPPGTVGPTGLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFD 1211 A RG G RGPPG G G+ GP GE+G++G P L + Sbjct: 1741 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800 Query: 1212 SFHENTRPPMPIL--EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR----GEPGA 1265 + R +P L EQ L PG P G PG K PGE G+ G L G+ G+PG Sbjct: 1801 KAGDPGRDGLPGLRGEQGL-PG--PSGPPGLPGK---PGEDGKPG--LNGKNGEPGDPGE 1852 Query: 1266 VGQMGSPGQQGAS 1278 G+ G G GAS Sbjct: 1853 DGRKGEKGDSGAS 1865 Score = 119 bits (299), Expect = 1e-26 Identities = 92/238 (38%), Positives = 111/238 (46%), Gaps = 40/238 (16%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG 1129 +PG GP+GP PG G G++GFPGP G G KGE+G G G +G PG G PG G Sbjct: 1463 SPGEQGPRGP---PGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKG 1519 Query: 1130 LQGPKGMRGLEGTAGLPGPP-----------GPRGFQ------GMAGARGTSGERGPPGT 1172 +GP G G +G G PG P GP+G + G GA G GERGPPG Sbjct: 1520 PEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL 1579 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228 V P G PGPKG+ G++G K D PP P+ + Sbjct: 1580 VLP-GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG--PPGPVGPRGRDGEV 1636 Query: 1229 -EPGTE-PLGSPGTRSKALVPGEWG-RGGRHLEG-------RGEPGAVGQMGSPGQQG 1276 E G E P G PG KA GE G RG + G +G+PG G+ GSPG G Sbjct: 1637 GEKGDEGPPGDPGLPGKA---GERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSG 1691 Score = 118 bits (296), Expect = 3e-26 Identities = 89/223 (39%), Positives = 102/223 (45%), Gaps = 21/223 (9%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP+G PG G G G G PG GPPG KG+ G G PG G G G G G Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 +GP G GL G AG G G G +G G +G G+ G G G G GPKG+RGE G Sbjct: 1642 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP 1701 Query: 1191 PQSLATLYQLVSQASHVSK-FDSFHENTRPPM--PIL-----EQKLE-----PGTEPLGS 1237 P L A + D E R P P L E+ +E PG P G Sbjct: 1702 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG--PQGD 1759 Query: 1238 PGTRSKALVPGEWGRGGRHLEGR----GEPGAVGQMGSPGQQG 1276 PG R A G+ RG L+GR G+PGA G G G G Sbjct: 1760 PGVRGPAGEKGD--RGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800 Score = 115 bits (289), Expect = 2e-25 Identities = 98/284 (34%), Positives = 122/284 (42%), Gaps = 62/284 (21%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLP---------GRNGTPGEQGFPGPRG 1099 P G+ P ++ + GPPG +G PG P GR+G GE+G GP G Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646 Query: 1100 PPGVKGEKGDHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP- 1146 PG+ G+ G+ GL G QG PG G G G GPKG RG G G P Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG 1706 Query: 1147 ---------------------GPPGPRGFQGMAGA---RGTSGERGPPGTVGPTGLPGPK 1182 GP GP+G G+ GA RG G RGPPG G G+ GP Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766 Query: 1183 GERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPIL--EQKLEPGTEPL 1235 GE+G++G P L + + R +P L EQ L PG P Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGL-PG--PS 1823 Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGR-GEPGAVGQMGSPGQQGAS 1278 G PG K PGE G+ G L G+ GEPG G+ G G++G S Sbjct: 1824 GPPGLPGK---PGEDGKPG--LNGKNGEPGDPGEDGRKGEKGDS 1862 Score = 115 bits (288), Expect = 3e-25 Identities = 128/482 (26%), Positives = 198/482 (41%), Gaps = 26/482 (5%) Query: 364 PRQGPAAAPALDTLPAPTSLV--LSQVTSSS--IRLSWTPAPRHPLKYLIVWRASRGGTP 419 PR+G A+ + P V L V S + +R++W P P + I W G Sbjct: 581 PREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGAS-GFRISWSTGSGPES 639 Query: 420 REVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479 + + A T++ L T Y V+V + G + T PL P R + + + Sbjct: 640 SQTLPPDSTA-TDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQAS 698 Query: 480 PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQS- 538 +V +TW GAT Y R S S G E+ + V LDGLEP +Y V V++ Sbjct: 699 SSSVTITWTRVPGATGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAH 756 Query: 539 LRGPEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGG 597 + G +G A + P + L + S D R+ W G R+ + SEGG Sbjct: 757 VAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAY-RLAWGRSEGG 815 Query: 598 HSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT--KKAPSPSQLSM 655 PGN SA + L +Y+VRVT L + ++ VTT + P+ L + Sbjct: 816 PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHV 875 Query: 656 TELPGDAVQLAWVAAAPS-GVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYD 714 + +++L W + G L++ W P G + + P L + L GL T+Y Sbjct: 876 VQRGEHSLRLRWEPVPRAQGFLLH---WQPEGGQEQSRVLGP-ELSSYHLDGLEPATQYR 931 Query: 715 VTILAYYRDGARSDPVSLRYTPSTVS-RSPPSNLALASETPDSLQVSWTPPLGRVLHYWL 773 V + G + S T T S R P L + + DS+ ++WT P+ R Y L Sbjct: 932 VRLSVL---GPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWT-PVSRASSYIL 987 Query: 774 TYAPASGLG---PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTA 830 ++ P G G P ++PG S + L+ Y ++ + R S T Sbjct: 988 SWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV 1047 Query: 831 CP 832 CP Sbjct: 1048 CP 1049 Score = 114 bits (285), Expect = 6e-25 Identities = 85/238 (35%), Positives = 101/238 (42%), Gaps = 42/238 (17%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPG-----------------------PRGPPGVKGEK 1107 PG GP+GPPG GR G GE G PG PRG GV+GE+ Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574 Query: 1108 GDHGL-----PGLQGHPGHQG---IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159 G GL PG +G PG +G + GR G G G G +G G PGPPGP G +G G Sbjct: 1575 GPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 G G+ GPPG GLPG GERG +G P + + Q E+ R Sbjct: 1635 EVGEKGDEGPPGD---PGLPGKAGERGLRGAPGVRGPVGEKGDQGDP-------GEDGRN 1684 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 P EP G PG + + G R RG+ G G G PG GA Sbjct: 1685 GSPGSSGPKGDRGEP-GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGA 1741 Score = 110 bits (276), Expect = 7e-24 Identities = 67/150 (44%), Positives = 74/150 (49%), Gaps = 22/150 (14%) Query: 1063 ACSCSSET--PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV------KGEKGDHGLPG 1114 AC E G GP G PGL G G GE G PG G PG KG++G G PG Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG------PRGFQGMAGARGTSGER- 1167 +G G +G G G+ G G G +G+AG PGPPG P G QG G RG GER Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752 Query: 1168 -------GPPGTVGPTGLPGPKGERGEKGE 1190 G PG G G PGP G RGEKGE Sbjct: 2753 VGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782 Score = 106 bits (265), Expect = 1e-22 Identities = 79/239 (33%), Positives = 108/239 (45%), Gaps = 62/239 (25%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGE---KGDHGLPGLQGH--------- 1118 PGP G +G PG+ G +G PG++G G GPPG +GE KGD G GL+G Sbjct: 2468 PGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILG 2527 Query: 1119 -PGHQGIPGRVGLQGPKGMRGLEG------------TAGLPGP------PGPRGFQGMAG 1159 PG +G G +G +GP+G+ G +G + G PG PG RG G G Sbjct: 2528 PPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG 2587 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKG--EPQSLATLYQLVSQASHVSKFDSFHENT 1217 G +G G PG+ G G+PG +GE+G+ G P+ L Sbjct: 2588 QPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG--------------------- 2626 Query: 1218 RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 E+ ++ G G + +A PG G G H GEPG GQ G+PG++G Sbjct: 2627 -------ERGVKGACGLDGEKGDKGEAGPPGRPGLAG-HKGEMGEPGVPGQSGAPGKEG 2677 Score = 92.0 bits (227), Expect = 3e-18 Identities = 52/122 (42%), Positives = 60/122 (49%), Gaps = 14/122 (11%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI------ 1124 PG PG G PG G G G++GF G GP G +GEKG+ G PG+ G PG G Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGPR--------GFQGMAGARGTSGERGPPGTVGPT 1176 PG G GP+G GL+G G GPPG R G G G +G G GP G G Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783 Query: 1177 GL 1178 L Sbjct: 2784 AL 2785 Score = 70.1 bits (170), Expect = 1e-11 Identities = 40/81 (49%), Positives = 46/81 (56%), Gaps = 5/81 (6%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG--LQGHPGHQGIPGR 1127 TPG G GP G G G PG G GPRGP G++G+KG+ G PG + G PG G PG Sbjct: 2705 TPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGE 2764 Query: 1128 VGLQG---PKGMRGLEGTAGL 1145 G QG P G RG +G A L Sbjct: 2765 RGEQGRPGPAGPRGEKGEAAL 2785 Score = 65.5 bits (158), Expect = 3e-10 Identities = 77/263 (29%), Positives = 117/263 (44%), Gaps = 30/263 (11%) Query: 612 TLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAA 671 TL PL S R C GG T R +P L ++E ++++ W AA+ Sbjct: 206 TLLPLVS------RRVCTTAGGVPVT---RPPDDSTSAPRDLVLSEPSSQSLRVQWTAAS 256 Query: 672 PSGVLVYQITWTPL-GEGKA-----HEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725 V Y++ +TPL G G+ E++VP + L GL TEY VT++A Y A Sbjct: 257 -GPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALY---A 312 Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785 S ++ T T + P L + + T SL V+W G Y +T+ SG GP + Sbjct: 313 NSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGAT-GYRVTWRVLSG-GPTQ 369 Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTAC---PALRPDGSLPG 842 + + V L DL+ T Y V VS ++ A S +T LRP L Sbjct: 370 QQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-VILGP 428 Query: 843 FDLMVAFSLVEKAYASIRGVAME 865 ++++++LV +A RG +E Sbjct: 429 TSILLSWNLVPEA----RGYRLE 447 Score = 65.5 bits (158), Expect = 3e-10 Identities = 99/387 (25%), Positives = 149/387 (38%), Gaps = 47/387 (12%) Query: 24 EQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVG 83 E A G L + E L+++W E G+L+ +P G EQ +L + + Sbjct: 865 EAPPALGTLHVVQRGEHSLRLRW-EPVPRAQGFLLHWQPEGGQ-EQSRVLGPELSSYHLD 922 Query: 84 GLSPSKGYTLQIFELTGSGRF----LLARREFV-IEDLKSSSLDRS-------------- 124 GL P+ Y +++ L +G + AR E + ++ +D S Sbjct: 923 GLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRA 982 Query: 125 -----SQRPLGS------GAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPA--GP--- 168 S RPL G+P+ P + S EP V++ S P GP Sbjct: 983 SSYILSWRPLRGPGQEVPGSPQTLPGISSS-QRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041 Query: 169 --QFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGD 226 Q P AD+VFL + H + V+A +GP VQVGL YS Sbjct: 1042 VTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHR 1101 Query: 227 AQTEWDLNSLSTKEQVLAAVRRLRY---KGGNTFTGLALTHVLGQNLQP-AAGLRPEAAK 282 + LN +L +R + Y G N T + H L P A G R Sbjct: 1102 PSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAH--RYMLAPDAPGRRQHVPG 1159 Query: 283 VVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDI-TVHSVLDF 341 V++L+ D + D+ + R + G+NV +G+ AD +LR LA + T +V D Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDG 1219 Query: 342 LQLGALAGLLSRLICQRLQGGSPRQGP 368 L L+ +CQ PR P Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRPEP 1246 Score = 55.8 bits (133), Expect = 3e-07 Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 51/151 (33%) Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---GPTGLPGPKGERGEKG 1189 PKG +G G GL G GP G G+ G G G +GPPG+ G G PG G G G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 + PGT G+PG + +PG Sbjct: 1312 RAGN------------------------------------PGTP--GAPGLKGSPGLPGP 1333 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280 RG+PG G G G+ GA Q Sbjct: 1334 ----------RGDPGERGPRGPKGEPGAPGQ 1354 Score = 34.7 bits (78), Expect = 0.60 Identities = 30/85 (35%), Positives = 36/85 (42%), Gaps = 19/85 (22%) Query: 1212 SFHENTRP-PMPIL---EQKLEPG-------TEPLGSPGTRSKALVPGEWG-------RG 1253 SF RP P P+ QK EPG P G PG + PG G +G Sbjct: 1237 SFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKG 1296 Query: 1254 GRHLEGR-GEPGAVGQMGSPGQQGA 1277 R G G PG+ G+ G+PG GA Sbjct: 1297 ERGFPGADGRPGSPGRAGNPGTPGA 1321 >gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo sapiens] Length = 921 Score = 208 bits (529), Expect = 3e-53 Identities = 155/472 (32%), Positives = 212/472 (44%), Gaps = 57/472 (12%) Query: 827 GQTACPALR-PDGSLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTR 885 G CP +R LPGFDL+ F V+KA AS R + + + L + Sbjct: 40 GNELCPKIRIGQDDLPGFDLISQFQ-VDKA-ASRRAIQRVVGSATLQVAYKLGNNVDFRI 97 Query: 886 RVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFH 945 ++YP+ LP E++ + R+ T ++ + +WQ+ + +G+ ++ +S+ + + Sbjct: 98 PTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSY 157 Query: 946 RDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAA 1005 + +LQ A F + +F +HK+ + V RS L+VDC ++ P+ G Sbjct: 158 KGLDGSLQTAAFS--NLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDID 215 Query: 1006 GFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACS 1065 GF LG+LA P+ S F+LQ + I C + C ELPA S Sbjct: 216 GFAVLGKLAD--NPQVS-VPFELQWMLIHCDPLRPRRETCHELPAR----------ITPS 262 Query: 1066 CSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 +++ GPPG QGPPG PG G PG G G RGP G G G G PG G PG G P Sbjct: 263 QTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTP 322 Query: 1126 GRVGLQGPKGMR---GLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT---------V 1173 G GL GP G G +G G PG PG RGF G RG G GPPGT V Sbjct: 323 GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRV 378 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 GP G PG +G G G P T+ FH+ P+ PG Sbjct: 379 GPVGDPGRRGPPGPPGPPGPRGTI--------------GFHDGD----PLCPNACPPGRS 420 Query: 1234 PL-GSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQGASTQGL 1282 G PG R GE G GR H G+ G +G++G+ G GA QGL Sbjct: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA--QGL 470 Score = 132 bits (333), Expect = 2e-30 Identities = 96/248 (38%), Positives = 107/248 (43%), Gaps = 42/248 (16%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG------LQGHPGHQG 1123 +PG PG GPPGLPG G G G PGP+G G GE+G+ G G L G G G Sbjct: 647 SPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706 Query: 1124 IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---------- 1173 PG GL+GP+G RGL G G GPPGPRG QG GA G G +GPPG Sbjct: 707 NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 766 Query: 1174 --------------------GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 G TGLPG G G G P Q+ + K Sbjct: 767 MRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 826 Query: 1214 HENTRPPMPILEQKLE---PGTEPLGSPGTRSKALVPG--EWGRGGRHLEGRGEPGAVGQ 1268 R P L +K E PG P G PG PG +GR GR E RG PG G Sbjct: 827 ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGE-RGPPGVAGI 885 Query: 1269 MGSPGQQG 1276 G PG G Sbjct: 886 PGVPGPPG 893 Score = 129 bits (325), Expect = 1e-29 Identities = 92/253 (36%), Positives = 112/253 (44%), Gaps = 47/253 (18%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 S+ PG PG G G PG+ G PGE G GP+G PG +GE G G PGL G G G PG Sbjct: 590 STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP----------------- 1169 GL GP G+ G++G G+ G PGP+G QG +G G +GERG Sbjct: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709 Query: 1170 -------------PGTVGPTGLPGPKGERGEKGE--------PQSLATLYQLVSQASHVS 1208 PG GP G PGP+G +GE+G P A Q + Q Sbjct: 710 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769 Query: 1209 KFDSFHENT----RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEP 1263 + F E RP PG P G PG + PG+ G G L G +G P Sbjct: 770 IQEHFAEMAASLKRPDSGATGLPGRPG--PPGPPGPPGENGFPGQMGIRG--LPGIKGPP 825 Query: 1264 GAVGQMGSPGQQG 1276 GA+G G G G Sbjct: 826 GALGLRGPKGDLG 838 Score = 129 bits (323), Expect = 2e-29 Identities = 86/218 (39%), Positives = 107/218 (49%), Gaps = 15/218 (6%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PG QG G PG G G++G G RG PG+ G KGD GLPG+ G G G+PG G Sbjct: 498 PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLP---GPKGE--- 1184 G G G G GLPG PG G +G+AG +G++G G PG +G +G P GP GE Sbjct: 558 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMP----ILEQKLEPGTEPLGSPGT 1240 RG +G P S L V K S P +P + K + G +G PG Sbjct: 618 RGPQGLPGSRGELGP-VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGP 674 Query: 1241 RSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQG 1276 + + GE G G L G PG G G+PG+ G Sbjct: 675 KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 712 Score = 127 bits (319), Expect = 7e-29 Identities = 92/240 (38%), Positives = 110/240 (45%), Gaps = 37/240 (15%) Query: 1053 DGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGD 1109 DGE P + GPPG GP G G G G G PGP+G PGV G G Sbjct: 489 DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTS---GE 1166 G+PG +G PG G PG GLQG G+ G+ G G+ G G G G G G S G+ Sbjct: 549 PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 608 Query: 1167 RGPPGTV---GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPI 1223 +GPPG V GP GLPG +GE G G P L L S P +P Sbjct: 609 QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS----------------PGLPG 652 Query: 1224 LEQKLEPGTEPLGSPGTRSKALVPGEWG----RGGRHLEGR-GEPGAVGQMGSPGQQGAS 1278 L PG P G PG + V GE G +G EG GE G +G +G PG +G++ Sbjct: 653 L-----PG--PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 705 Score = 124 bits (312), Expect = 4e-28 Identities = 96/251 (38%), Positives = 107/251 (42%), Gaps = 69/251 (27%) Query: 1071 PGPPGPQGPPGLPGRNGT---------------PGEQGFPGPRGPPGVKGEKGDHGLPGL 1115 PG GP GPPG PG GT PG G+PG G G KG KG+ G PG Sbjct: 384 PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 443 Query: 1116 QGHPGH---QGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------QGMAGARGT 1163 QGH G QG G VG QGP G +GL G G+ G G +G QG+ GA G Sbjct: 444 QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503 Query: 1164 SGERGPPGTVGPTG------------LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFD 1211 G+RGPPG GP G LPGPKG+ G G V D Sbjct: 504 QGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG-----------------VDGRD 546 Query: 1212 SFHENTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLE-----GRGEPGA 1265 P MP K EPG P G G + VPG G G E G+PG Sbjct: 547 GI-----PGMP--GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599 Query: 1266 VGQMGSPGQQG 1276 +G G PGQQG Sbjct: 600 MGNSGKPGQQG 610 Score = 104 bits (259), Expect = 6e-22 Identities = 61/125 (48%), Positives = 66/125 (52%), Gaps = 13/125 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP GPPG PGE GFPG G G+ G KG G GL+G G G G G Sbjct: 792 PGRPGPPGPPG------PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGP 845 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG- 1189 G +G GL G GLPG PGP + G G GERGPPG G G+PGP G G G Sbjct: 846 PG-RGPNGLPGAIGLPGDPGPASY----GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900 Query: 1190 -EPQS 1193 EP S Sbjct: 901 CEPAS 905 Score = 54.7 bits (130), Expect = 6e-07 Identities = 33/80 (41%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPG +GP GLPG G PG+ G P G G GE+G G+ G+ G PG G PG G Sbjct: 844 GPPG-RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901 Query: 1132 GPKGMRGLEGTAGLPGPPGP 1151 P G P P Sbjct: 902 EPASCTMQAGQRAFNKGPDP 921 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 183 bits (465), Expect = 8e-46 Identities = 144/496 (29%), Positives = 213/496 (42%), Gaps = 67/496 (13%) Query: 828 QTACPALRPDGSLP--GFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTR 885 ++ CP P + GFD+++ + +K I+ + P G + + L+ Sbjct: 214 ESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQ---LSPKKIKG---YEVTSKVDLSE 267 Query: 886 RVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFH 945 S+V+P LPP + V R ++ + LW++ D +P + V L+ K L + Sbjct: 268 LTSNVFPEGLPPSYVFVSTQRF---KVKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTT 324 Query: 946 RDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAA 1005 Q TF +V+ +F +H++ + V V LY+D +++ +PL P Sbjct: 325 TSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLH-----PVL 379 Query: 1006 GFVTLGR--LAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETC--PAFV 1061 G + G+ + K G + + F +Q L+I C + + CE+P +GE P+ V Sbjct: 380 GILINGQTQIGKYSG-KEETVQFDVQKLRIYCDPEQNNRETACEIPGF-NGECLNGPSDV 437 Query: 1062 SA----CSCSSETPGPPGPQGPPGLPGRNGTPGE-------------------------- 1091 + C C PG GP+G PGLPG G PG+ Sbjct: 438 GSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG 497 Query: 1092 -QGFPGPRGPPGVKGEKGD---------HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEG 1141 +G PG +G PG G+KGD HG+PG +G G +G G G G KG +G +G Sbjct: 498 ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557 Query: 1142 TAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLV 1201 AG PG PGP G G G G G G G G G PG G RGE G P L+ Sbjct: 558 NAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIP-GFPGNRGLM 616 Query: 1202 SQASHVSKFDSFHENTRPPMP-ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260 Q + + P MP ++ PG G+PG++ PG G G + Sbjct: 617 GQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP--GTPGSKGSKGEPGIQGMPGAS-GLK 673 Query: 1261 GEPGAVGQMGSPGQQG 1276 GEPGA G G PG G Sbjct: 674 GEPGATGSPGEPGYMG 689 Score = 125 bits (314), Expect = 3e-28 Identities = 77/206 (37%), Positives = 99/206 (48%), Gaps = 12/206 (5%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP G PG G++G G GF G G PG G+ G G PG+ G PG++G+ G+ G Sbjct: 562 PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE 621 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 GP G +G +G G+PG G G G G G+ G +G PG G G G KGE G G Sbjct: 622 IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEW 1250 P + Q K + + I QK E G + G PG + + G Sbjct: 682 PGEPGYMGLPGIQGKKGDKGNQGEKG------IQGQKGENGRQ--GIPGQQG---IQGHH 730 Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G G E +GEPG G +GS G+ G Sbjct: 731 GAKGERGE-KGEPGVRGAIGSKGESG 755 Score = 124 bits (312), Expect = 4e-28 Identities = 70/196 (35%), Positives = 113/196 (57%), Gaps = 6/196 (3%) Query: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236 P D+VF++DGS+S+G +F+ VK +L ++ F+IGP +QVG+ QYS E L S Sbjct: 35 PTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSY 94 Query: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDV 296 + E + AAV + Y GGNT TG A+ L ++ K+ +++TDGKSQDDV Sbjct: 95 DSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVLTDGKSQDDV 151 Query: 297 HTAARVLKDLGVNVFAVGV-KNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355 AA+ +D + +FA+GV ++AELR +A+ P V V D++ + + ++ + + Sbjct: 152 KDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKL 211 Query: 356 CQRLQGGSPRQGPAAA 371 C+ + P + P AA Sbjct: 212 CE--ESVCPTRIPVAA 225 Score = 121 bits (304), Expect = 4e-27 Identities = 74/207 (35%), Positives = 99/207 (47%), Gaps = 6/207 (2%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG 1129 +PG G G PG PG++GT GE G PG G G+ G+KG+ G PG QG G G+PG +G Sbjct: 582 SPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG 641 Query: 1130 LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG 1189 G G G G+ G G PG +G G +G +G G G PG G GLPG +G++G+KG Sbjct: 642 SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 Q + +K EPG G+ G++ ++ V G Sbjct: 702 NQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVR--GAIGSKGESGVDGL 759 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G G +G+PG G G PG G Sbjct: 760 MGPAG----PKGQPGDPGPQGPPGLDG 782 Score = 116 bits (291), Expect = 1e-25 Identities = 81/226 (35%), Positives = 111/226 (49%), Gaps = 22/226 (9%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG G +G PG G G PG G PG +G G KG +G+ G+ G +G G QGIPG+ G+ Sbjct: 667 PGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726 Query: 1131 Q---GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187 Q G KG RG +G G+ G G +G G+ G G +G +G PG GP G PG G+ G Sbjct: 727 QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGR 786 Query: 1188 KGEPQSLATL--------YQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSP 1238 + Q + + ++ Q+ + D ++ P +P + P P G P Sbjct: 787 EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP-EGPRGLP 845 Query: 1239 GTRSKALVPGEWG-------RGGRHLEGR-GEPGAVGQMGSPGQQG 1276 G + VPG G RG + L GR GE G+ G G PG+QG Sbjct: 846 GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQG 890 Score = 115 bits (289), Expect = 2e-25 Identities = 70/172 (40%), Positives = 84/172 (48%), Gaps = 11/172 (6%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPG QG G PG G G G PG G PG KG KG+ G+ G+ G G +G PG G Sbjct: 623 GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G G GL G G G G +G +G+ G +G +G +G PG G G G KGERGEKGEP Sbjct: 683 GEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEP 742 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243 + SK +S + P Q +PG P G PG K Sbjct: 743 GVRGAI---------GSKGESGVDGLMGPAGPKGQPGDPG--PQGPPGLDGK 783 Score = 98.6 bits (244), Expect = 3e-20 Identities = 63/155 (40%), Positives = 73/155 (47%), Gaps = 45/155 (29%) Query: 1071 PGPPGPQGPPGLPGRNGTP----------------------------------GEQGFPG 1096 PG PGPQGPPGL G+ G + G PG Sbjct: 769 PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828 Query: 1097 PRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQG 1156 GPPG G +G GLPGL PG G+PG VG+ G G+RGL+G LPG G +G QG Sbjct: 829 IPGPPGPIGPEGPRGLPGL---PGRDGVPGLVGVPGRPGVRGLKG---LPGRNGEKGSQG 882 Query: 1157 MAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G GE+GPPG GP G PG E G G+P Sbjct: 883 F----GYPGEQGPPGPPGPEGPPGISKE-GPPGDP 912 Score = 91.7 bits (226), Expect = 4e-18 Identities = 54/124 (43%), Positives = 63/124 (50%), Gaps = 15/124 (12%) Query: 1064 CSCSSETPGPPGPQGP---------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 C +PG PGP GP PGLPGR+G PG G PG G G+KG G +G G Sbjct: 820 CLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKG 879 Query: 1115 LQ--GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 Q G+PG QG PG G +GP G+ G PG PG G G G G G+ GPPG Sbjct: 880 SQGFGYPGEQGPPGPPGPEGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935 Query: 1173 VGPT 1176 P+ Sbjct: 936 CDPS 939 Score = 91.7 bits (226), Expect = 4e-18 Identities = 54/113 (47%), Positives = 58/113 (51%), Gaps = 6/113 (5%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPGP GP G G G PG G PG G PG G +G GLPG G G QG G G Sbjct: 830 PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGE 888 Query: 1131 QGPKGMRGLEGTAGLP--GPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP 1181 QGP G G EG G+ GPPG G G G G G +G PG P G+ P Sbjct: 889 QGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPG---PPGICDP 938 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 182 bits (462), Expect = 2e-45 Identities = 153/533 (28%), Positives = 221/533 (41%), Gaps = 100/533 (18%) Query: 817 AGRSEAVSATGQTACPALRPDG-----------SLPGFDLMVAFSLVEKAYASIRGVAME 865 A S V + +CP LR +G + GFDL +FSL S + Sbjct: 20 ASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----- 74 Query: 866 PSAFGGTPTFTLFK--DAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTA 923 T FK A L R ++P LP E+++ + R+ +E + LWQ+ Sbjct: 75 ----------TCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLN 124 Query: 924 EDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVR 983 + P + +++D GKK + + + + F +E+R +F +HK+ +++ + Sbjct: 125 QQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVIS 184 Query: 984 LYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADED 1043 LY+DC +A R E + G + A P +L L+I CS ++ Sbjct: 185 LYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKP----VDIELHQLKIYCSANLIAQE 240 Query: 1044 RCCELPASRD------GETCPAFVSA------------------CSCSSE--------TP 1071 CCE+ ++ G ++V+A C C P Sbjct: 241 TCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAP 300 Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---------KGEKGDHGLPGLQGHPGHQ 1122 G PG +G G PG NG G GFPG +G G KGE+G+ G P L G G Sbjct: 301 GSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGEN 360 Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPP---------GPRGFQGMAGARGTSGERGPPGTV 1173 G+ G +G GP G +G +G G PGPP GP+G G G RG G+ GPPG Sbjct: 361 GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP 420 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFH----ENTRPPMP----ILE 1225 GP PGP G G +G Q+L Y ++ + + E P P Sbjct: 421 GP---PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKG 477 Query: 1226 QKLEPGTEPL--GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 QK EPG EP G G R + V G G G G+PG G +GSPG +G Sbjct: 478 QKGEPG-EPFTKGEKGDRGEPGVIGSQGVKGE----PGDPGPPGLIGSPGLKG 525 Score = 132 bits (331), Expect = 3e-30 Identities = 92/239 (38%), Positives = 116/239 (48%), Gaps = 19/239 (7%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 G+ PA + S PG PGP G PG PG G G+ GFPGP GP G G G G+P Sbjct: 875 GDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 G QGI G+ G +GPKG RG +G G G G RG G+ G +G G GPPG Sbjct: 935 GA------QGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988 Query: 1174 GPTGLPGPKGERGEKGEP--QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP- 1230 G G PG +G G G P + A ++ + + + F E R + + + KL Sbjct: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEE--RMAVFLSQLKLPAA 1046 Query: 1231 --GTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQGASTQGL 1282 + G PG K +PG G +G R +G RGEPG +G GSPG G S GL Sbjct: 1047 MLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGL 1104 Score = 127 bits (320), Expect = 5e-29 Identities = 91/236 (38%), Positives = 104/236 (44%), Gaps = 35/236 (14%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLP--GRNGTPG---------EQGFPGPRGP 1100 R G P S PG PGP GPPG+P RNG +PGP GP Sbjct: 787 RTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGP 846 Query: 1101 PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA 1160 PG KG+ G G PG G PG +G PG G +GP G G+ G +G PG PGP G G G Sbjct: 847 PGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGE 906 Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP 1220 RG G+ G PG GP+G PG G+ G G +Q D + R Sbjct: 907 RGPVGDIGFPGPEGPSGKPGINGKDGIPG------------AQGIMGKPGDRGPKGERGD 954 Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 I PG GS G R K PG G G + G PG G MGSPG QG Sbjct: 955 QGI------PGDR--GSQGERGK---PGLTGMKGA-IGPMGPPGNKGSMGSPGHQG 998 Score = 119 bits (298), Expect = 2e-26 Identities = 85/232 (36%), Positives = 104/232 (44%), Gaps = 43/232 (18%) Query: 1071 PGPPGPQGPPGLPGRN-----------------------GTPGEQGFPGPRGPPGVKGEK 1107 PGPPGP GPPG+ G + G GE G PG G G KG+K Sbjct: 420 PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQK 479 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER 1167 G+ G P +G G +G PG +G QG KG G G GL G PG +G QG AG+ G G Sbjct: 480 GEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP 539 Query: 1168 GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQK 1227 G G G G+PG +G +GEKG+P + L PP L Sbjct: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAG----------PPGKSLPG- 588 Query: 1228 LEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQ--MGSPGQQGA 1277 EPG + G+PG GE G G H G PG +G +G PG+ GA Sbjct: 589 -EPGLD--GNPGAPGPRGPKGERGLPGVH----GSPGDIGPQGIGIPGRTGA 633 Score = 117 bits (294), Expect = 5e-26 Identities = 95/266 (35%), Positives = 110/266 (41%), Gaps = 64/266 (24%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRG-------PPGVKGEKGDHGLPG--LQG 1117 S+ + GP GP G GLPG +G PG+QG G +G PPG+ G KG+ G PG L G Sbjct: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPG 588 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPG-----------------PPGPRGFQGMAGA 1160 PG G PG G +GPKG RGL G G PG P G G QG G Sbjct: 589 EPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGL 648 Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL-------------------- 1200 G G G PG G G G G G G+P +L L + Sbjct: 649 PGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKS 708 Query: 1201 ----VSQASHVSKFDSFHE----NTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWG 1251 A K+DS R P I PG E P GS G R +PGE Sbjct: 709 NKGEEGGAGEPGKYDSMARKGDIGPRGPPGI------PGREGPKGSKGERGYPGIPGE-- 760 Query: 1252 RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 +G L+G G PGA G G PG G Sbjct: 761 KGDEGLQGIPGIPGAPGPTGPPGLMG 786 Score = 115 bits (289), Expect = 2e-25 Identities = 79/224 (35%), Positives = 110/224 (49%), Gaps = 28/224 (12%) Query: 1065 SCSSETPG---PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 +C + PG G +G G PG+ + +G GPRGPPG+ G +G G G +G+P Sbjct: 698 NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP-- 755 Query: 1122 QGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP 1181 GIPG +G +G++G+ G G PGP GP G G G G +G +G G+ GP G PGP Sbjct: 756 -GIPGE---KGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811 Query: 1182 KGERG-EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240 G G E +++LY++ + S+ PP P K +PG P+G PG Sbjct: 812 PGPPGIPFNERNGMSSLYKIKGGVN----VPSYPGPPGPPGP----KGDPG--PVGEPGA 861 Query: 1241 RSKALVPGEWG-RGGRHLEG-------RGEPGAVGQMGSPGQQG 1276 + G G +G R G G+PGA G G PG+ G Sbjct: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPG 905 Score = 107 bits (266), Expect = 1e-22 Identities = 83/227 (36%), Positives = 95/227 (41%), Gaps = 25/227 (11%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P + GE F PG G QG G PG G PG G PG +G G G G Sbjct: 475 PKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168 G PG G PG GIPG+ G++G KG G G G PG PGP+G G G G Sbjct: 535 PRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPG----KSLPG 588 Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-- 1226 PG G G PGP+G +GE+G P H S D + P Q Sbjct: 589 EPGLDGNPGAPGPRGPKGERGLP------------GVHGSPGDIGPQGIGIPGRTGAQGP 636 Query: 1227 KLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSP 1272 EPG + P G PG PG G GR G+PG G G P Sbjct: 637 AGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD----GKPGLPGPPGDP 679 Score = 86.3 bits (212), Expect = 2e-16 Identities = 64/215 (29%), Positives = 75/215 (34%), Gaps = 87/215 (40%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG---------------- 1114 PGP GP G PG+ G++G PG QG G G G KGE+GD G+PG Sbjct: 916 PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGM 975 Query: 1115 --------------LQGHPGHQGIPGRVGLQG---------------------------- 1132 G PGHQG PG G+ G Sbjct: 976 KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 Query: 1133 -------------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG-----ERG 1168 G G +G G PG PGP+G++G G RG G G Sbjct: 1036 VFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPG 1095 Query: 1169 PPGTV-----GPTGLPGPKGERGEKGEPQSLATLY 1198 PGT G G PGP+G G G LY Sbjct: 1096 LPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLY 1130 Score = 56.6 bits (135), Expect = 1e-07 Identities = 34/82 (41%), Positives = 40/82 (48%), Gaps = 10/82 (12%) Query: 1063 ACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP--------PGVKGEKGDH--GL 1112 A +++ G PGP G GLPG G PG QG+ G +G PG G G GL Sbjct: 1045 AAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGL 1104 Query: 1113 PGLQGHPGHQGIPGRVGLQGPK 1134 PG G PG QG PG G P+ Sbjct: 1105 PGSPGAPGPQGPPGPSGRCNPE 1126 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 169 bits (429), Expect = 1e-41 Identities = 143/486 (29%), Positives = 196/486 (40%), Gaps = 71/486 (14%) Query: 831 CPALRPDGS-----------LPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFK 879 CP++R +G + GFDLM FS+ E G G P Sbjct: 223 CPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFP------ 276 Query: 880 DAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKK 939 + + DV+P LP E+ V R + +E + +WQ+ + P + + LD K Sbjct: 277 ---VVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENK 333 Query: 940 SLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEM 999 ++ Y F V +F +HK+ +++ V L++DC V P+ E Sbjct: 334 AVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEER 393 Query: 1000 GSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPAS-------- 1051 + G +G+ R S F LQ + I C A+ + CC++P+ Sbjct: 394 ENIDIQGKTVIGK----RLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVT 449 Query: 1052 ------------RDGETCPAFVSA--CSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGP 1097 G F+ CSC + G G GP GLPG G + G GP Sbjct: 450 EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG---DIGAIGP 506 Query: 1098 RGPPGVKGEKGDHGL----PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRG 1153 G PG KGEKGD G+ G +G G G+PG G G KGMRG G G PG PG Sbjct: 507 VGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE-- 564 Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 GM G +G G GPPG VG GL G +GE+G +GE K Sbjct: 565 -VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL-------DGFPGKPGDT 616 Query: 1214 HENTRP-PMPILEQKLEPG-TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGS 1271 + RP P + + E G P G PG VPG + +G PG G G+ Sbjct: 617 GQQGRPGPSGVAGPQGEKGDVGPAGPPG------VPGSVVQQEGLKGEQGAPGPRGHQGA 670 Query: 1272 PGQQGA 1277 PG GA Sbjct: 671 PGPPGA 676 Score = 143 bits (360), Expect = 1e-33 Identities = 90/214 (42%), Positives = 105/214 (49%), Gaps = 16/214 (7%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPGP G PGLPG G PG+ G PGP GPPG G G G PG +G PG +G G G Sbjct: 722 PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G +G G +G AG PG G G G G G GE+G G G GLPG KG+RGEKGE Sbjct: 782 PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841 Query: 1191 -----PQSLATLYQLVSQASHV-SKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSK 1243 P L L + + + E P +P EPG + G G + Sbjct: 842 AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP-----GEPGLQGRPGELGPQGP 896 Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG G+ G H G PGA G G+PG GA Sbjct: 897 TGPPGAKGQEGAH----GAPGAAGNPGAPGHVGA 926 Score = 140 bits (352), Expect = 1e-32 Identities = 109/296 (36%), Positives = 136/296 (45%), Gaps = 17/296 (5%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P G G P GF + A GPR S A L + + D D P G Sbjct: 1268 PEGARGPP---GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK---DGDTGPTGPQGPQG 1321 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEK---GDHG 1111 P + S PGP G G G G NG+PG GF GPRGPPG GEK G G Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381 Query: 1112 LPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171 +PG G PG +G G G++G KG G +G G PG PG +G G+ G +G GE GP Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP-- 1439 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQ--ASHVSKFDSFHENTRPPMPILEQKLE 1229 VGP G PG G G +GE S+ TL +L+ + + ++ PP + + Sbjct: 1440 -VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGR 1498 Query: 1230 PGTE-PLGSPGTRSKALVPGEWGRGGR-HLEGRGEP-GAVGQMGSPGQQGASTQGL 1282 PG P G G +A GE GR G+ LEG P G G+ G+ G GA GL Sbjct: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGL 1554 Score = 139 bits (350), Expect = 2e-32 Identities = 97/283 (34%), Positives = 128/283 (45%), Gaps = 64/283 (22%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG 1111 +DG+T P GP GPQGP G PG+NG+PG G PGP G PG KG KG++G Sbjct: 1307 KDGDTGPT------------GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354 Query: 1112 LPGLQG---------HPGHQGIPGRVG------------------LQGPKGMRGLEGTAG 1144 PGL G PG +G+PG+ G ++G KG G +G G Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414 Query: 1145 LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQ----- 1199 PG PG +G G+ G +G GE GP G GP G PG G RGE ++L L Q Sbjct: 1415 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474 Query: 1200 -LVSQASHV------SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG- 1251 L ++ +++ + S PP P + L P+G PG + + G G Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534 Query: 1252 ---RGGRHLEG---------RGEPGAVGQMGSPGQQGASTQGL 1282 +G R +G RGE G G G PG+ G + GL Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL 1577 Score = 138 bits (347), Expect = 4e-32 Identities = 75/184 (40%), Positives = 113/184 (61%), Gaps = 3/184 (1%) Query: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238 D+VFL+D S S+G F++V+ ++A+++ FE+GPD+ +VG+ +YS T ++L + Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPE---AAKVVILVTDGKSQDD 295 +E+V AA RRL Y GGNT TG AL ++ ++ P AG RP +V IL+TDG+SQD Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157 Query: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355 V AA G+ +FAVGV A + EL +AS P+ V V DF + + G L R + Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217 Query: 356 CQRL 359 C+ + Sbjct: 218 CENV 221 Score = 132 bits (332), Expect = 2e-30 Identities = 84/221 (38%), Positives = 101/221 (45%), Gaps = 21/221 (9%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQ-------- 1122 PG PGP G G+ G G PG QG PG GPPG +G G G+PG +G G Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256 Query: 1123 -------GIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 G+PG G +GP G +G G +G PGP G G G+ G G G+ G G GP Sbjct: 1257 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 1316 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G GP+G G+ G P S + SK EN P +P P EP Sbjct: 1317 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK----GENGSPGLPGFLGPRGPPGEP- 1371 Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G G K VPG+ G G E RG+PG G G PG +G Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKGPPGGKG 1411 Score = 132 bits (331), Expect = 3e-30 Identities = 97/263 (36%), Positives = 113/263 (42%), Gaps = 39/263 (14%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPG---------RNGTPG--------- 1090 P DG A S GPPGPQGP GLPG R+G PG Sbjct: 1202 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 1261 Query: 1091 EQGFPGP---RGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL------------QGPKG 1135 E G PGP RGPPG KG GD G PG +G G G+PG+ GL QGP+G Sbjct: 1262 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 1321 Query: 1136 MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLA 1195 RG G G PG PG G G G +G+ GE G PG G G GP GE GEKG P Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381 Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255 + + D + + P Q +PG PG + + G G G Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI-----PGHKGHTGLMGPQGLPGE 1436 Query: 1256 HLEGRGEPGAVGQMGSPGQQGAS 1278 + G PG GQ G PG +G S Sbjct: 1437 N-GPVGPPGPPGQPGFPGLRGES 1458 Score = 131 bits (329), Expect = 5e-30 Identities = 94/242 (38%), Positives = 107/242 (44%), Gaps = 44/242 (18%) Query: 1072 GPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 GP G +G PGLPG G PGE G GP GPPG KG++G HG PG G+PG G G Sbjct: 868 GPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---- 1184 G GP G G G G PG G RG +G AG G+ G GP G G GLPGP G+ Sbjct: 928 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 987 Query: 1185 ----RGEKGEPQSLATLY---------------QLVS--------QASHVSKFDSFHENT 1217 RG G P L T Q V S S+ D Sbjct: 988 EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047 Query: 1218 RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PP P PG + GSPG+R PG G GR G PG G+ G PG+ G Sbjct: 1048 GPPGP----SGPPGDK--GSPGSRGLPGFPGPQGPAGRD----GAPGNPGERGPPGKPGL 1097 Query: 1278 ST 1279 S+ Sbjct: 1098 SS 1099 Score = 125 bits (315), Expect = 2e-28 Identities = 86/238 (36%), Positives = 106/238 (44%), Gaps = 32/238 (13%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG---LPGLQGHPGHQGIPG 1126 T G G GPPGLPG G G QG G RG G G+KGD G +PG G PG+ G PG Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 1204 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER---------GPPGTVGPTG 1177 G+ G G G++G+ G GPPGP+G G+ G G G+ G PG G G Sbjct: 1205 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264 Query: 1178 LPGPKGERGEKG-----------EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ 1226 LPGP+G RG G P+ + L Q K D T P P + Sbjct: 1265 LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK-DGDTGPTGPQGPQGPR 1323 Query: 1227 KLEPGTEPLGSPGTRSKALVPGEWGRGGRH--------LEGRGEPGAVGQMGSPGQQG 1276 GSPG + PG+ G G + L RG PG G+ G PG++G Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381 Score = 123 bits (309), Expect = 1e-27 Identities = 88/225 (39%), Positives = 111/225 (49%), Gaps = 45/225 (20%) Query: 1072 GPPGPQGPPGLPG----RNGTPGEQGFPGPRG------PPGVKGE---KGDHGLPGLQGH 1118 G GP GPPG+PG + G GEQG PGPRG PPG +G +G G PGLQG Sbjct: 635 GDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGL 694 Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178 G +G G G+ G G++G G G+PGPPGP G G+ G G G+ GPPG PTG Sbjct: 695 RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPG---PTGP 751 Query: 1179 P------GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 P GP G G KGEP E+ P P L ++ G Sbjct: 752 PGKDGPNGPPGPPGTKGEPGERG-------------------EDGLPGKPGLRGEI--GE 790 Query: 1233 EPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 + L G PG + +A +PG G G E +G+ G G++G PG +G Sbjct: 791 QGLAGRPGEKGEAGLPGAPGFPGVRGE-KGDQGEKGELGLPGLKG 834 Score = 123 bits (309), Expect = 1e-27 Identities = 87/263 (33%), Positives = 105/263 (39%), Gaps = 76/263 (28%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL------PGLQGHPGHQGI 1124 PG GP+GPPG PG G PG++G PG G PG KGE+GD G+ PG +G PG GI Sbjct: 1359 PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI 1418 Query: 1125 PGR---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA--------------------- 1160 PG GL GP+G+ G G G PGPPG GF G+ G Sbjct: 1419 PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLET 1478 Query: 1161 --------------RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASH 1206 + + G GPPG G GLPG G GE G P Sbjct: 1479 RLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ------------- 1525 Query: 1207 VSKFDSFHENTRPPMPILEQ--KLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG----- 1259 + P P E+ K +PG +G G +PG+ G G +G Sbjct: 1526 ----GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1581 Query: 1260 --------RGEPGAVGQMGSPGQ 1274 G PG G G PGQ Sbjct: 1582 GPQGETGPAGHPGLPGPPGPPGQ 1604 Score = 123 bits (308), Expect = 1e-27 Identities = 84/224 (37%), Positives = 100/224 (44%), Gaps = 58/224 (25%) Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPGHQGIPG 1126 PPGP G PGLPG G G G PG G G KGE G GLPG QG G +G G Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA------RGTSGERGPPGTVGPTGLPG 1180 VG +G +G G+ G G PG PGP G G+AGA +G+ G+ GPPG GP+GLPG Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 1181 PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240 GE G++G +PG P G PG Sbjct: 1238 IPGEEGKEGRDG------------------------------------KPG--PPGEPGK 1259 Query: 1241 RSKALVPGEWGRGG-----RHLEGRGEPGAVGQ---MGSPGQQG 1276 + +PG G G H G PG G+ MG PGQ+G Sbjct: 1260 AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303 Score = 122 bits (306), Expect = 2e-27 Identities = 88/245 (35%), Positives = 103/245 (42%), Gaps = 50/245 (20%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV----------------KGEKGDHGLPGL 1115 G G +G GLPG G GE+G GP GPPG+ +G KG+ G PGL Sbjct: 819 GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 878 Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 G PG QG PG +G QGP G G +G G G PG G G G G G GPPG+VG Sbjct: 879 PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938 Query: 1176 TGL---PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GL PG GERGEKG + + P +P PG Sbjct: 939 PGLRGTPGKDGERGEKG----------AAGEEGSPGPVGPRGDPGAPGLP-----GPPGK 983 Query: 1233 EPLGSPGTRSKALVPGEWGR---------------GGRHLEG-RGEPGAVGQMGSPGQQG 1276 G PG R +PG G GG+ ++G RG PG G GS G G Sbjct: 984 GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG 1043 Query: 1277 ASTQG 1281 G Sbjct: 1044 IGVAG 1048 Score = 119 bits (298), Expect = 2e-26 Identities = 92/268 (34%), Positives = 114/268 (42%), Gaps = 49/268 (18%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGL-----PGRNGTPGEQGFPGPRGPPGV 1103 R E C PG PG +G PG+ PG +G PG++G PG RG PG Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGF 1070 Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQG------------------PKGMRGLEGTAGL 1145 G +G G G G+PG +G PG+ GL P G GL G G Sbjct: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF 1130 Query: 1146 PGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQA- 1204 G G G G G G GE GPPG GP G+ GP+G +GE+G + Q Q Sbjct: 1131 KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG---QKGDQGH 1187 Query: 1205 SHVSKFDSFHENTRPP----------MPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRG 1253 V F N PP P ++ PG E P G G +PGE G+ Sbjct: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQG--SPGKEGPPGPQGPSGLPGIPGEEGKE 1245 Query: 1254 GRHLEGR----GEPGAVGQMGSPGQQGA 1277 GR +G+ GEPG G+ G PG +GA Sbjct: 1246 GR--DGKPGPPGEPGKAGEPGLPGPEGA 1271 Score = 112 bits (281), Expect = 2e-24 Identities = 89/265 (33%), Positives = 108/265 (40%), Gaps = 98/265 (36%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGE--QGFPGPRGPPGVKGE--------------------- 1106 +PGP GP+G PG PG G PG+ G PG RG PG+ G Sbjct: 962 SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021 Query: 1107 --KGDHGLPGLQGHPGHQGIPG-----RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159 KGD G PG+ G PG +G PG G GP G +G G+ GLPG PGP+G G G Sbjct: 1022 CVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081 Query: 1160 ARGTSGERGPPGTVG------------------------PTGLPGPKGERGEKGEPQSLA 1195 A G GERGPPG G P GLPG G +G+KG P Sbjct: 1082 APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG--- 1138 Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255 +PG E G+ G + +A PG G G Sbjct: 1139 ---------------------------------KPGRE--GTEGKKGEAGPPGLPGPPG- 1162 Query: 1256 HLEG----RGEPGAVGQMGSPGQQG 1276 + G +GE GA G++G G QG Sbjct: 1163 -IAGPQGSQGERGADGEVGQKGDQG 1186 Score = 112 bits (280), Expect = 2e-24 Identities = 96/284 (33%), Positives = 114/284 (40%), Gaps = 63/284 (22%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPP---GLPGRNGTPGEQGFPGPRGPPGVKGEKGDH 1110 G T P + PG G G P G PG +G PG G PG RG PG GE+G+ Sbjct: 895 GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 954 Query: 1111 GLPGLQGHP---GHQGIPGRVGLQGPKGM-----RGLEGTAGLPGPPGP----------- 1151 G G +G P G +G PG GL GP G GL G+ GLPGP G Sbjct: 955 GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014 Query: 1152 ---------RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQS--LATLYQL 1200 +G +G G G+ G RG PG +G G PGP G G+KG P S L Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073 Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-----------------GSPGTRSK 1243 A + E P P L L PG L G PG + Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133 Query: 1244 ALVPGEWGRGGRHLEGR----------GEPGAVGQMGSPGQQGA 1277 VPG+ GR G EG+ G PG G GS G++GA Sbjct: 1134 KGVPGKPGREG--TEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175 Score = 96.3 bits (238), Expect = 2e-19 Identities = 59/130 (45%), Positives = 67/130 (51%), Gaps = 21/130 (16%) Query: 1058 PAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKG 1108 PA++ + S PGPPGP G GLPGR G GE G PG P GP G +G KG Sbjct: 1489 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545 Query: 1109 DHGLPG--LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE 1166 D G PG L+G G GIPG+ G G GLPG PGP+G G AG G G Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPG-------YAKDGLPGIPGPQGETGPAGHPGLPGP 1598 Query: 1167 RGPPGTVGPT 1176 GPPG P+ Sbjct: 1599 PGPPGQCDPS 1608 >gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] Length = 2296 Score = 159 bits (402), Expect = 2e-38 Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + A +PPP L + P T+ +T Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286 Query: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542 W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342 Query: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402 Query: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461 Query: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520 Query: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776 G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T PA Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634 Score = 148 bits (373), Expect = 4e-35 Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425 P + + +P PT L + + ++R++W P P L +V + E+ + Sbjct: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317 Query: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485 + L NL TEY+VSV +YE LRG T L P + + +T + + Sbjct: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376 Query: 486 TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544 W P A T Y +R P G E V R + L L PG +Y VS+ +L G E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 545 SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603 S I ++ PR L + + + W+ VR R+TY GG+S E Sbjct: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494 Query: 604 -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659 PG+ ++AT+ L YT+ V + G S + ++ + PSQ+ +T++ Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 +++ + W+ ++ S V Y++T TP G G + + + GL EY V++ Sbjct: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777 A G S P+ + V+ P P++L TP SL WTPP ++ Y + P Sbjct: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668 Query: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814 GP K +++ S V + L ATKY V V A+ Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705 Score = 145 bits (367), Expect = 2e-34 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%) Query: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421 ++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130 Query: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481 V + + S + L EY+ ++ + +G + PL PP L L A P Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187 Query: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T LT W+ S T Y + +P + +G E V + D L PG +Y VSV Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591 +++ + S P + PP L F+++ D RV W AP P LVR + Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304 Query: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651 V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+ Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362 Query: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710 + +++ ++ + W+A + + Y+I P G+ E VP + + L L Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421 Query: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770 TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V + Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477 Query: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531 Score = 127 bits (320), Expect = 5e-29 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + P P+ L T + Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 D +++ W + + + ++P+ E E+S+ + VL L TEY V++ Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778 + Y + + LR T P+ + + T +S V W P + Y + + P Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395 Query: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828 G + VP +R+ +TL +L T+Y +VS + GR E+ GQ Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443 Score = 115 bits (288), Expect = 3e-25 Identities = 119/490 (24%), Positives = 213/490 (43%), Gaps = 26/490 (5%) Query: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437 P L + T +S+ +SW AP ++Y + GG +E V G ++ + L Sbjct: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509 Query: 438 SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493 +Y ++V+ + G ++ + P + + V ++ + W PS+ Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553 T Y V +P + G + + + E+ ++GL+P +Y VSV + + P G ++ Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628 Query: 554 TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609 T+ P L F+ V+ + W P V+L VRVT G AP +++ Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685 Query: 610 SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668 S + L +T Y V V L S G VTT + SP + + +T+ + ++W Sbjct: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745 Query: 669 AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728 + + +Q+ P + ++ ++ + + GL T+Y + + D ARS Sbjct: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803 Query: 729 PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788 PV + ++ + PSNL + TP+SL VSW PP R+ Y + Y G P + V Sbjct: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859 Query: 789 VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT-ACPAL--RPDGSLPGFD 844 P + T+ L+ T+Y + V A+ +SE + +T P L P +L G + Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919 Query: 845 LMVAFSLVEK 854 ++ S V+K Sbjct: 1920 ILDVPSTVQK 1929 Score = 104 bits (259), Expect = 6e-22 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774 ++ +D S P+S P+ PP++L + PD+++V+W PP + ++ + Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Y+P +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 94.4 bits (233), Expect = 6e-19 Identities = 112/484 (23%), Positives = 182/484 (37%), Gaps = 42/484 (8%) Query: 360 QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418 Q S P A+ T+PAPT L +QVT +S+ WTP Y + V + G Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674 Query: 419 PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477 +E+ + ++S + L T+Y VSV+ + + +G+VTT + PPR + Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734 Query: 478 VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T T+ ++W+ T + V PA+ + +R ++ + GL+PG DY++ + Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596 +L S I A T + P +L F + ++ V W+ P R+ + Sbjct: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850 Query: 597 GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653 G + P T AT+ L T YT+ V L S L GR T + P Sbjct: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP----- 1905 Query: 654 SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEY 713 + LP + + PS V P G + I +PG G P +G+ + Sbjct: 1906 QLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-GYDTGNGIQLPGTSGQQ--PSVGQQMIF 1962 Query: 714 DVTILAYYRDGARSDPVSLR---YTPST-----VSRSPPS---------------NLALA 750 + + P+ R Y P+ + P N + Sbjct: 1963 EEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTG 2022 Query: 751 SETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVL 810 E +SW P Y ++ P VPG + TL L Y ++ Sbjct: 2023 QEALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081 Query: 811 VSAI 814 V A+ Sbjct: 2082 VEAL 2085 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 32.3 bits (72), Expect = 3.0 Identities = 15/64 (23%), Positives = 27/64 (42%) Query: 485 LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544 ++W P + Y++ C P E + V L GL G Y + V++L+ + Sbjct: 2031 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090 Query: 545 SEAR 548 + R Sbjct: 2091 HKVR 2094 >gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] Length = 2176 Score = 159 bits (402), Expect = 2e-38 Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + A +PPP L + P T+ +T Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286 Query: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542 W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342 Query: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402 Query: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461 Query: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520 Query: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776 G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T PA Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634 Score = 148 bits (373), Expect = 4e-35 Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425 P + + +P PT L + + ++R++W P P L +V + E+ + Sbjct: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317 Query: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485 + L NL TEY+VSV +YE LRG T L P + + +T + + Sbjct: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376 Query: 486 TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544 W P A T Y +R P G E V R + L L PG +Y VS+ +L G E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 545 SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603 S I ++ PR L + + + W+ VR R+TY GG+S E Sbjct: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494 Query: 604 -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659 PG+ ++AT+ L YT+ V + G S + ++ + PSQ+ +T++ Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 +++ + W+ ++ S V Y++T TP G G + + + GL EY V++ Sbjct: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777 A G S P+ + V+ P P++L TP SL WTPP ++ Y + P Sbjct: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668 Query: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814 GP K +++ S V + L ATKY V V A+ Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705 Score = 145 bits (367), Expect = 2e-34 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%) Query: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421 ++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130 Query: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481 V + + S + L EY+ ++ + +G + PL PP L L A P Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187 Query: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T LT W+ S T Y + +P + +G E V + D L PG +Y VSV Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591 +++ + S P + PP L F+++ D RV W AP P LVR + Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304 Query: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651 V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+ Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362 Query: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710 + +++ ++ + W+A + + Y+I P G+ E VP + + L L Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421 Query: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770 TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V + Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477 Query: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531 Score = 127 bits (320), Expect = 5e-29 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + P P+ L T + Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 D +++ W + + + ++P+ E E+S+ + VL L TEY V++ Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778 + Y + + LR T P+ + + T +S V W P + Y + + P Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395 Query: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828 G + VP +R+ +TL +L T+Y +VS + GR E+ GQ Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443 Score = 115 bits (289), Expect = 2e-25 Identities = 113/467 (24%), Positives = 202/467 (43%), Gaps = 23/467 (4%) Query: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437 P L + T +S+ +SW AP ++Y + GG +E V G ++ + L Sbjct: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509 Query: 438 SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493 +Y ++V+ + G ++ + P + + V ++ + W PS+ Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553 T Y V +P + G + + + E+ ++GL+P +Y VSV + + P G ++ Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628 Query: 554 TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609 T+ P L F+ V+ + W P V+L VRVT G AP +++ Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685 Query: 610 SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668 S + L +T Y V V L S G VTT + SP + + +T+ + ++W Sbjct: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745 Query: 669 AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728 + + +Q+ P + ++ ++ + + GL T+Y + + D ARS Sbjct: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803 Query: 729 PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788 PV + ++ + PSNL + TP+SL VSW PP R+ Y + Y G P + V Sbjct: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859 Query: 789 VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPAL 834 P + T+ L+ T+Y + V A+ +SE + +T AL Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEAL 1906 Score = 104 bits (259), Expect = 6e-22 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774 ++ +D S P+S P+ PP++L + PD+++V+W PP + ++ + Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Y+P +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 94.7 bits (234), Expect = 5e-19 Identities = 96/367 (26%), Positives = 155/367 (42%), Gaps = 24/367 (6%) Query: 360 QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418 Q S P A+ T+PAPT L +QVT +S+ WTP Y + V + G Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674 Query: 419 PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477 +E+ + ++S + L T+Y VSV+ + + +G+VTT + PPR + Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734 Query: 478 VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T T+ ++W+ T + V PA+ + +R ++ + GL+PG DY++ + Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596 +L S I A T + P +L F + ++ V W+ P R+ + Sbjct: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850 Query: 597 GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653 G + P T AT+ L T YT+ V L S L GR K L Sbjct: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR----KKTGQEAL 1906 Query: 654 SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTE 712 S T ++W A Y I+ P+G + + + VPG +A L GL R Sbjct: 1907 SQT-------TISW--APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 1957 Query: 713 YDVTILA 719 Y++ + A Sbjct: 1958 YNIIVEA 1964 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 62.8 bits (151), Expect = 2e-09 Identities = 111/525 (21%), Positives = 185/525 (35%), Gaps = 87/525 (16%) Query: 69 QEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARR--------------EFVIE 114 QE + AT+ GL P YT+ ++ +TG G + + + + Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1551 Query: 115 DLKSSSLD----RSSQRPLG-------SGAPEPTPSHTGSPDPEQAS----EPQVAFTPS 159 D++ +S+ SS G P PT + T PD + + +P V + S Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611 Query: 160 QDPRTPAGPQFRCLP------PVPADMVFL------VDGSWSIGHSHFQQVKDFLASVIA 207 + P+G + P P D+ F + W+ + Q+ + V Sbjct: 1612 VYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNV---QLTGYRVRVTP 1668 Query: 208 PFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLG 267 + GP K ++ L S + ++TK +V Y +T T V+ Sbjct: 1669 KEKTGPMK-EINLAPDSSSVVVSGLM--VATKYEVSV------YALKDTLTSRPAQGVVT 1719 Query: 268 --QNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRL 325 +N+ P R A + +++ + T G V AV N R Sbjct: 1720 TLENVSPPRRARVTDATETTITISWRTKTETIT--------GFQVDAVPA-NGQTPIQRT 1770 Query: 326 LASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVL 385 + R T+ G G ++ L + R P A + AP++L Sbjct: 1771 IKPDVRSYTI--------TGLQPGTDYKIYLYTLNDNA-RSSPVVIDASTAIDAPSNLRF 1821 Query: 386 SQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTE--LHNLASRTEYL 443 T +S+ +SW P PR + I+ G PREVV TE + L TEY Sbjct: 1822 LATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 1880 Query: 444 VSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPA 503 + V + E L G T A++ T+ +W P + Y++ C P Sbjct: 1881 IYVIALKNNQKSEPLIGRKKTGQ---------EALSQTTI--SWAPFQDTSEYIISCHPV 1929 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548 E + V L GL G Y + V++L+ + + R Sbjct: 1930 GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 1974 >gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] Length = 2355 Score = 155 bits (392), Expect = 2e-37 Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + A +PPP L + P T+ +T Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286 Query: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542 W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342 Query: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402 Query: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461 Query: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520 Query: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776 G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630 Score = 146 bits (369), Expect = 1e-34 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434 L +PT + S +T++S + W APR + Y I G PRE V S L Sbjct: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416 Query: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493 NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+ Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549 +Y + +E V + + GL+PG DY ++V ++ G P S+ Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535 Query: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608 I RT + P + +DV ++ V W + PV RVT G +T+ G + Sbjct: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594 Query: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668 T T+ L + Y V V P G S L T P L+ T++ D++++AW Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652 Query: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725 +P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D Sbjct: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709 Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785 S P L T ST +P ++L TP SL WTPP ++ Y + P GP K Sbjct: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766 Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814 +++ S V + L ATKY V V A+ Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795 Score = 145 bits (367), Expect = 2e-34 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%) Query: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421 ++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130 Query: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481 V + + S + L EY+ ++ + +G + PL PP L L A P Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187 Query: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T LT W+ S T Y + +P + +G E V + D L PG +Y VSV Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591 +++ + S P + PP L F+++ D RV W AP P LVR + Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304 Query: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651 V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+ Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362 Query: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710 + +++ ++ + W+A + + Y+I P G+ E VP + + L L Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421 Query: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770 TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V + Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477 Query: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531 Score = 127 bits (320), Expect = 5e-29 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + P P+ L T + Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 D +++ W + + + ++P+ E E+S+ + VL L TEY V++ Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778 + Y + + LR T P+ + + T +S V W P + Y + + P Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395 Query: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828 G + VP +R+ +TL +L T+Y +VS + GR E+ GQ Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443 Score = 114 bits (286), Expect = 5e-25 Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%) Query: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418 +G SP P + + P+ + ++ V +SI + W P+ Y + G Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477 P + GP + L EY+VSV+ G + L T + P+ L Sbjct: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642 Query: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527 V ++ + W+ P + Y V S +P GEE+ E+Q GL Sbjct: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693 Query: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586 PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L Sbjct: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750 Query: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643 VRVT G AP +++S + L +T Y V V L S G VT Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809 Query: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702 T + SP + + +T+ + ++W + + +Q+ P + ++ ++ + Sbjct: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868 Query: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762 + GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW Sbjct: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924 Query: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821 PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE Sbjct: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983 Query: 822 AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854 + +T P L P +L G +++ S V+K Sbjct: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2019 Score = 104 bits (259), Expect = 6e-22 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774 ++ +D S P+S P+ PP++L + PD+++V+W PP + ++ + Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Y+P +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 34.3 bits (77), Expect = 0.79 Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 2/83 (2%) Query: 466 PLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDG 525 P P P + A++ T+ +W P + Y++ C P E + V L G Sbjct: 2073 PRPYPPNVGQEALSQTTI--SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 2130 Query: 526 LEPGRDYEVSVQSLRGPEGSEAR 548 L G Y + V++L+ + + R Sbjct: 2131 LTRGATYNIIVEALKDQQRHKVR 2153 >gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] Length = 2330 Score = 155 bits (392), Expect = 2e-37 Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + A +PPP L + P T+ +T Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286 Query: 487 WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542 W P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342 Query: 543 EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402 Query: 601 QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461 Query: 661 DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ A Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520 Query: 720 YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776 G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 777 PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630 Score = 146 bits (369), Expect = 1e-34 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434 L +PT + S +T++S + W APR + Y I G PRE V S L Sbjct: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416 Query: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493 NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+ Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549 +Y + +E V + + GL+PG DY ++V ++ G P S+ Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535 Query: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608 I RT + P + +DV ++ V W + PV RVT G +T+ G + Sbjct: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594 Query: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668 T T+ L + Y V V P G S L T P L+ T++ D++++AW Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652 Query: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725 +P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D Sbjct: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709 Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785 S P L T ST +P ++L TP SL WTPP ++ Y + P GP K Sbjct: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766 Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814 +++ S V + L ATKY V V A+ Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795 Score = 145 bits (367), Expect = 2e-34 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%) Query: 365 RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421 ++ P A TL +S+ ++VT ++I ++WTPAPR K + R S+GG PRE Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130 Query: 422 VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481 V + + S + L EY+ ++ + +G + PL PP L L A P Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187 Query: 482 TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536 T LT W+ S T Y + +P + +G E V + D L PG +Y VSV Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247 Query: 537 QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591 +++ + S P + PP L F+++ D RV W AP P LVR + Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304 Query: 592 VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651 V +E + + +P + + L L T Y V V+ +Y S+ L GR T SP+ Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362 Query: 652 QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710 + +++ ++ + W+A + + Y+I P G+ E VP + + L L Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421 Query: 711 TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770 TEY V+I+A +G P+ + STVS P +L + + TP SL +SW P V + Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477 Query: 771 YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Y +TY G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531 Score = 127 bits (320), Expect = 5e-29 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + P P+ L T + Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 D +++ W + + + ++P+ E E+S+ + VL L TEY V++ Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778 + Y + + LR T P+ + + T +S V W P + Y + + P Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395 Query: 779 SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828 G + VP +R+ +TL +L T+Y +VS + GR E+ GQ Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443 Score = 115 bits (287), Expect = 4e-25 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%) Query: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418 +G SP P + + P+ + ++ V +SI + W P+ Y + G Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477 P + GP + L EY+VSV+ G + L T + P+ L Sbjct: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642 Query: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527 V ++ + W+ P + Y V S +P GEE+ E+Q GL Sbjct: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693 Query: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586 PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L Sbjct: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750 Query: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643 VRVT G AP +++S + L +T Y V V L S G VT Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809 Query: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702 T + SP + + +T+ + ++W + + +Q+ P + ++ ++ + Sbjct: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868 Query: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762 + GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW Sbjct: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924 Query: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821 PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE Sbjct: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983 Query: 822 AVSATGQTACPALRPDGSLPGFD 844 + G+ P + PG+D Sbjct: 1984 PL--IGRKKTVQKTPFVTHPGYD 2004 Score = 104 bits (259), Expect = 6e-22 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774 ++ +D S P+S P+ PP++L + PD+++V+W PP + ++ + Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Y+P +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 46.2 bits (108), Expect = 2e-04 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424 R P A + AP++L T +S+ +SW P PR + I+ G PREVV Sbjct: 1891 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 1949 Query: 425 EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456 TE + L TEY + V P Y+ G G Sbjct: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009 Query: 457 GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489 L G P PP T PR ++W P Sbjct: 2010 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069 Query: 490 SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548 + Y++ C P E + V L GL G Y + V++L+ + + R Sbjct: 2070 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2128 >gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] Length = 2477 Score = 152 bits (383), Expect = 3e-36 Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425 P + + +P T L +T SSI L WTP + Y I A+ G P E V+ Sbjct: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317 Query: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485 + L +Y +SV + GG TA +PPP L + P T+ + Sbjct: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376 Query: 486 TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541 TW P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433 Query: 542 PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ Sbjct: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610 Query: 719 AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775 A G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667 Query: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T Sbjct: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721 Score = 146 bits (369), Expect = 1e-34 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434 L +PT + S +T++S + W APR + Y I G PRE V S L Sbjct: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507 Query: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493 NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+ Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549 +Y + +E V + + GL+PG DY ++V ++ G P S+ Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626 Query: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608 I RT + P + +DV ++ V W + PV RVT G +T+ G + Sbjct: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685 Query: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668 T T+ L + Y V V P G S L T P L+ T++ D++++AW Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743 Query: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725 +P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D Sbjct: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800 Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785 S P L T ST +P ++L TP SL WTPP ++ Y + P GP K Sbjct: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857 Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814 +++ S V + L ATKY V V A+ Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886 Score = 136 bits (343), Expect = 1e-31 Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + + P + LS ++ Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 ++ L W S ++ Y+IT GEG E V ++G + GL +YD++++ Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777 +G S P +L + PP++L + PD+++V+W PP + ++ + Y+P Sbjct: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395 Query: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447 Score = 133 bits (335), Expect = 1e-30 Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + +P L+ +T ++ L Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286 Query: 487 WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541 W P +T R + + GE E+ + VG V GLEPG DY++SV +L Sbjct: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343 Query: 542 PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596 G A + + PP L F+++ D RV W AP P LVR + V +E Sbjct: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400 Query: 597 GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656 + + +P + + L L T Y V V+ +Y S+ L GR T SP+ + + Sbjct: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458 Query: 657 ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 ++ ++ + W+A + + Y+I P G+ E VP + + L L TEY V Sbjct: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775 +I+A +G P+ + STVS P +L + + TP SL +SW P V +Y +TY Sbjct: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573 Query: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622 Score = 114 bits (286), Expect = 5e-25 Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%) Query: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418 +G SP P + + P+ + ++ V +SI + W P+ Y + G Sbjct: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674 Query: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477 P + GP + L EY+VSV+ G + L T + P+ L Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733 Query: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527 V ++ + W+ P + Y V S +P GEE+ E+Q GL Sbjct: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784 Query: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586 PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L Sbjct: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841 Query: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643 VRVT G AP +++S + L +T Y V V L S G VT Sbjct: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900 Query: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702 T + SP + + +T+ + ++W + + +Q+ P + ++ ++ + Sbjct: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959 Query: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762 + GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW Sbjct: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015 Query: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821 PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE Sbjct: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074 Query: 822 AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854 + +T P L P +L G +++ S V+K Sbjct: 2075 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2110 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 91.3 bits (225), Expect = 5e-18 Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774 ++ +D S P+S P ++L+ T S+ + WTP ++ Y +T Sbjct: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832 A P V + + T+ L+ Y + V + G S + T QTA P Sbjct: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 32.3 bits (72), Expect = 3.0 Identities = 15/64 (23%), Positives = 27/64 (42%) Query: 485 LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544 ++W P + Y++ C P E + V L GL G Y + V++L+ + Sbjct: 2212 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271 Query: 545 SEAR 548 + R Sbjct: 2272 HKVR 2275 >gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] Length = 2421 Score = 152 bits (383), Expect = 3e-36 Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425 P + + +P T L +T SSI L WTP + Y I A+ G P E V+ Sbjct: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317 Query: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485 + L +Y +SV + GG TA +PPP L + P T+ + Sbjct: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376 Query: 486 TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541 TW P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+ Sbjct: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433 Query: 542 PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599 E E+ +R R T L P + FSD++ ++ V W + R+ + G Sbjct: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + P + S TL L+ T Y V + L S L G+ +T + P L + Sbjct: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 ++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+ Sbjct: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610 Query: 719 AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775 A G A S P+S+ Y PS + + +S+ V W P V Y +T Sbjct: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667 Query: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T Sbjct: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721 Score = 146 bits (369), Expect = 1e-34 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%) Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434 L +PT + S +T++S + W APR + Y I G PRE V S L Sbjct: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507 Query: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493 NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+ Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566 Query: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549 +Y + +E V + + GL+PG DY ++V ++ G P S+ Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626 Query: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608 I RT + P + +DV ++ V W + PV RVT G +T+ G + Sbjct: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685 Query: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668 T T+ L + Y V V P G S L T P L+ T++ D++++AW Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743 Query: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725 +P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D Sbjct: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800 Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785 S P L T ST +P ++L TP SL WTPP ++ Y + P GP K Sbjct: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857 Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814 +++ S V + L ATKY V V A+ Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886 Score = 136 bits (343), Expect = 1e-31 Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%) Query: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427 P A L APT+L T S++ + WTP Y + +R G PR+ V Sbjct: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047 Query: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483 + L NL +EY VS+ I G+ TT + +PP VT T+ Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103 Query: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543 +TW P A + +G E REV +++ GL PG +Y ++Q LR + Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160 Query: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599 +A + L+PP +L ++ V WE + P + R+T + G G+S Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659 + + +S T LS Y V V + S ++ + + P + LS ++ Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279 Query: 660 GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718 ++ L W S ++ Y+IT GEG E V ++G + GL +YD++++ Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339 Query: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777 +G S P +L + PP++L + PD+++V+W PP + ++ + Y+P Sbjct: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395 Query: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 +S+ + + V L +L T+Y V VS++Y S + +T Sbjct: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447 Score = 133 bits (335), Expect = 1e-30 Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%) Query: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370 F +GV+ + E PR++T S + G G+ Q L+ G R P Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426 + L PT+L L + + +SW + + Y I + G G E VV Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227 Query: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486 +S NL+ EY VSV+ + + + + +P L+ +T ++ L Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286 Query: 487 WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541 W P +T R + + GE E+ + VG V GLEPG DY++SV +L Sbjct: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343 Query: 542 PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596 G A + + PP L F+++ D RV W AP P LVR + V +E Sbjct: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400 Query: 597 GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656 + + +P + + L L T Y V V+ +Y S+ L GR T SP+ + + Sbjct: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458 Query: 657 ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 ++ ++ + W+A + + Y+I P G+ E VP + + L L TEY V Sbjct: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775 +I+A +G P+ + STVS P +L + + TP SL +SW P V +Y +TY Sbjct: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573 Query: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 G P + +VPG++S T+ L+ Y + V A+ G S A S Sbjct: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622 Score = 115 bits (287), Expect = 4e-25 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%) Query: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418 +G SP P + + P+ + ++ V +SI + W P+ Y + G Sbjct: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674 Query: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477 P + GP + L EY+VSV+ G + L T + P+ L Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733 Query: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527 V ++ + W+ P + Y V S +P GEE+ E+Q GL Sbjct: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784 Query: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586 PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L Sbjct: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841 Query: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643 VRVT G AP +++S + L +T Y V V L S G VT Sbjct: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900 Query: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702 T + SP + + +T+ + ++W + + +Q+ P + ++ ++ + Sbjct: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959 Query: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762 + GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW Sbjct: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015 Query: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821 PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE Sbjct: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074 Query: 822 AVSATGQTACPALRPDGSLPGFD 844 + G+ P + PG+D Sbjct: 2075 PL--IGRKKTVQKTPFVTHPGYD 2095 Score = 102 bits (255), Expect = 2e-21 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%) Query: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414 CQ LQ GP +T P +S + W P P H KY++ WR Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648 Query: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469 G +E + G S + L Y + I + G E R TT+ P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514 P T +VT T ++W S + + V + E + ++ Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572 V + L PGR Y V+V + E E I + + T AP P V + Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826 Query: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632 V W P+ R+ Y S G S + P A S TL L Y + + + Sbjct: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886 Query: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686 S+ + TG + PSP L E+ V + W S V Y++ P+ Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945 Query: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745 H +P + T A + GL Y + A G S P++ + T P+ Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001 Query: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805 NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+ Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060 Query: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847 +Y V + AI G E+ ATG L+P S+P ++ V Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098 Score = 91.3 bits (225), Expect = 5e-18 Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423 +Q P DT+P+P L +VT + + WTP Y + V + G + + Sbjct: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954 Query: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483 E+ L+ Y VF + G + L TT L P L T TV Sbjct: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013 Query: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541 + W P A T Y + + +G+ + V + L L+P +Y VS+ +++G Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072 Query: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599 E +A G+ + + PP + ++V+ + W APR + V S+GG + Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127 Query: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658 + E ++ S + L+ Y + L G + + +V T +P P+ L + Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185 Query: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715 P V ++W + + Y+IT TP +G + E V + + L EY+V Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245 Query: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774 ++ +D S P+S P ++L+ T S+ + WTP ++ Y +T Sbjct: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301 Query: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832 A P V + + T+ L+ Y + V + G S + T QTA P Sbjct: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359 Score = 74.7 bits (182), Expect = 5e-13 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%) Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503 Y G+GE + T P P +T P + + W QPS + Y++R P Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648 Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560 + G +E + + GL+PG YE + S++ E T + + P Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708 Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604 ++++ + V W A V RV Y SE G Q + Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768 Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 P ATS + L Y V V + G S + T +P ++ ++ ++ Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828 Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724 + W + + + Y+I ++P EG + E+++P + L L +Y++TI A + Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886 Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780 S PV ++ TP + + P +L T + + WTPP V Y + P + Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945 Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833 L E +P +R + + L Y V A+ S+ ++A T A Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999 Score = 65.5 bits (158), Expect = 3e-10 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%) Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699 T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663 Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749 + + GL Y+ +++ + G + + S T +TV+ +P S L Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723 Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804 SE T S VSW V + + Y + + + +P + V +PDL Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783 Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861 KY V V I G + +T QT P PD ++ D ++V +S + R Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842 Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892 + PS G + L + A + +SD+ P Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872 Score = 46.2 bits (108), Expect = 2e-04 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%) Query: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424 R P A + AP++L T +S+ +SW P PR + I+ G PREVV Sbjct: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 2040 Query: 425 EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456 TE + L TEY + V P Y+ G G Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2100 Query: 457 GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489 L G P PP T PR ++W P Sbjct: 2101 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2160 Query: 490 SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548 + Y++ C P E + V L GL G Y + V++L+ + + R Sbjct: 2161 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2219 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 144 bits (363), Expect = 5e-34 Identities = 95/231 (41%), Positives = 115/231 (49%), Gaps = 41/231 (17%) Query: 1072 GPPGPQGPPGLPG------------RNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP 1119 GP G +GP GLPG G PG GFPGP+GP G G+ GD G GL G Sbjct: 460 GPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGAR 519 Query: 1120 GHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---GTVGPT 1176 G G G G QGP G +G++G G GPPGP GFQG+ G G +GE G P G G Sbjct: 520 GAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEF 579 Query: 1177 GLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG----- 1231 GLPGP G RGE+G P S A+ + + PP P K EPG Sbjct: 580 GLPGPAGPRGERGPPGE--------SGAAGPTGPIGSRGPSGPPGPD-GNKGEPGVVGAV 630 Query: 1232 -----TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 + P G PG R A +PG G+G +GEPG G++G+PG+ GA Sbjct: 631 GTAGPSGPSGLPGERGAAGIPG--GKG-----EKGEPGLRGEIGNPGRDGA 674 Score = 134 bits (336), Expect = 7e-31 Identities = 94/258 (36%), Positives = 110/258 (42%), Gaps = 36/258 (13%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPG---RNGTPGEQGFPGPRGPPGVKGEKGDH 1110 GE PA S + PG GPQGPPG G + G GE G GP GPPG++G G Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSR 405 Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP---GPRGFQGMAGARGTSGER 1167 GLPG G G G PG G GP G+RG G AG PG P GPRG G G G +G+ Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE 465 Query: 1168 GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR--------- 1218 GP G G G PGP G G +GEP ++ D H Sbjct: 466 GPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525 Query: 1219 -------PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG-------RHLEGR---- 1260 PP P Q ++ G G PG +PG G G R L G Sbjct: 526 GNNGAQGPPGP---QGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLP 582 Query: 1261 GEPGAVGQMGSPGQQGAS 1278 G G G+ G PG+ GA+ Sbjct: 583 GPAGPRGERGPPGESGAA 600 Score = 133 bits (335), Expect = 1e-30 Identities = 90/206 (43%), Positives = 97/206 (47%), Gaps = 20/206 (9%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP G GPPG PG G GE G G GP G G +G+ GLPGL G G G PG GL Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G KG GL G AG PG PGPRG G GA G +G RG G GP G KGE G KGEP Sbjct: 307 GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG---SKGESGNKGEP 363 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEW 1250 S S E R P PG L GSPG+R +PG Sbjct: 364 G---------SAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRG---LPGAD 411 Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276 GR G G PG+ G G G +G Sbjct: 412 GRAG----VMGPPGSRGASGPAGVRG 433 Score = 122 bits (307), Expect = 2e-27 Identities = 96/273 (35%), Positives = 111/273 (40%), Gaps = 61/273 (22%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL-------------------------- 1082 P RDGE P + PGPPGP GPPGL Sbjct: 49 PPGRDGEDGP---------TGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR 99 Query: 1083 --PGRNGTPGEQGFPGPRGPPG---------VKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 PG G PG QGF GP G PG +G G G G GHPG G PG G+ Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV 159 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR---GTSGERGPPGTVGPTGLPGPKGERGEK 1188 GP+G RG GT GLPG G RG G+ G + G G +G PG G G PG G RG Sbjct: 160 GPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLP 219 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 GE + ++ S D P PI PG G+PG + + G Sbjct: 220 GERGRVGAPGPAGARGS-----DGSVGPVGPAGPI-GSAGPPGFP--GAPGPKGEIGAVG 271 Query: 1249 EWGRGGRHLEGRGE---PGAVGQMGSPGQQGAS 1278 G G RGE PG G +G PG GA+ Sbjct: 272 NAGPAG-PAGPRGEVGLPGLSGPVGPPGNPGAN 303 Score = 120 bits (302), Expect = 6e-27 Identities = 90/253 (35%), Positives = 104/253 (41%), Gaps = 55/253 (21%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPG---EQGFPGPRGPPGVKG 1105 PA GE P S + + G GP GPPG G G PG G GP GP G+ G Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPG 643 Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA----- 1160 E+G G+PG +G G G+ G +G G G RG G G PGP G G +G AGA Sbjct: 644 ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703 Query: 1161 ----RGTSGERGPPGTVGPTGL---------PGPKGERGEKGEPQSLATLYQLVSQASHV 1207 RG+ GERG G GP G PG KGERG KG Sbjct: 704 PAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKG------------------ 745 Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGA 1265 P E + T P+G+ G PG G RG G G PGA Sbjct: 746 --------------PKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGA 791 Query: 1266 VGQMGSPGQQGAS 1278 G+ G PG G S Sbjct: 792 AGRTGPPGPSGIS 804 Score = 120 bits (301), Expect = 8e-27 Identities = 93/288 (32%), Positives = 116/288 (40%), Gaps = 59/288 (20%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPR---------- 1098 PA G+ P ++ ++ GPPGP G G PG G G++G GPR Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832 Query: 1099 -----GPPGVKGEKGDHGLPGLQGHPGHQ------GIPGRVGLQGPKGMRGLEGTAGLPG 1147 GPPG GEKG G G G PG G PG +GL G +G RGL G AG G Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892 Query: 1148 PPGPRGFQGMAGAR---------------GTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192 PGP G G GAR G +G G PG GP G G G +GE+G P Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952 Query: 1193 SLATLYQLVSQASHVSKFDSFHENTR---------------------PPMPILEQKLEPG 1231 ++ + + H + R P I K EPG Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012 Query: 1232 TE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 + P G PG + + G G G H + +G PG+VG G G G S Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGD-QGAPGSVGPAGPRGPAGPS 1059 Score = 120 bits (301), Expect = 8e-27 Identities = 61/115 (53%), Positives = 67/115 (58%), Gaps = 3/115 (2%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP GP GP G+ G G PGE+G PRG PG+KG G GLPG+ GH G QG PG VG Sbjct: 994 GPRGPSGPQGIRGDKGEPGEKG---PRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPA 1050 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 GP+G G G AG G G G G AG RG G +GP G GP G PGP G G Sbjct: 1051 GPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Score = 119 bits (299), Expect = 1e-26 Identities = 86/229 (37%), Positives = 98/229 (42%), Gaps = 20/229 (8%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ---GFPGPRGPPGVKGEKGDH 1110 G+T PA + G G G PG PG G G Q GFPG G PG KG +G + Sbjct: 124 GQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHN 183 Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170 GL GL+G PG G+ G G G G G G GLPG G G G AGARG+ G GP Sbjct: 184 GLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPV 243 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230 G GP G GP G G G + V A P P E L Sbjct: 244 GPAGPIGSAGPPGFPGAPGPKGEIGA----VGNAGPAG----------PAGPRGEVGLPG 289 Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278 + P+G PG + G G G L G G PG G G PG GA+ Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAG--LPGVAGAPGLPGPRGIPGPVGAA 336 Score = 119 bits (297), Expect = 2e-26 Identities = 82/213 (38%), Positives = 102/213 (47%), Gaps = 28/213 (13%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G GP G G +G GE G GP+GPPG GE+G G G G G G PG G Sbjct: 343 GLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSP 402 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPTGLPGPKGERGEK 1188 G +G+ G +G AG+ GPPG RG G AG RG +G+ G PG +GP GLPG G G Sbjct: 403 GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462 Query: 1189 GE--PQSLATLYQLVSQASHVSKFDSFHENTRP-PMPILEQKLEPGTEPLGSPGTRSKAL 1245 G+ P L + + RP P+ + EPG +G PG + Sbjct: 463 GKEGPVGLPGI------------------DGRPGPIGPAGARGEPGN--IGFPGPKGPTG 502 Query: 1246 VPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 PG+ G +G L G RG PG G G+ G G Sbjct: 503 DPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPG 535 Score = 118 bits (295), Expect = 4e-26 Identities = 82/211 (38%), Positives = 101/211 (47%), Gaps = 21/211 (9%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL- 1130 GP G +GPPG PGR+G G G PGP GPPG PGL G+ Q VGL Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGP---------PGLGGNFAAQYDGKGVGLG 89 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 GP G+ G G G G PGP+GFQG AG G G+ GP G GP G PG GE G G+ Sbjct: 90 PGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGK 149 Query: 1191 PQSLATLYQLVSQASH----VSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246 P + Q + F + R + K +P G+PG + + Sbjct: 150 PGRPGERGVVGPQGARGFPGTPGLPGF-KGIRGHNGLDGLKGQP-----GAPGVKGEPGA 203 Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PGE G G+ RG PG G++G+PG GA Sbjct: 204 PGENGTPGQ-TGARGLPGERGRVGAPGPAGA 233 Score = 117 bits (293), Expect = 7e-26 Identities = 77/208 (37%), Positives = 87/208 (41%), Gaps = 30/208 (14%) Query: 1072 GPPGPQGPPGLPGRNGTPG---EQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 GP G G PG G G G E G GP GP G G G +G PG G G G PG Sbjct: 727 GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G G G G G +G+ GPPGP G G G RG G++GP G G G GP G GEK Sbjct: 787 GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEK 846 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 G T PP Q L LG PG+R + +PG Sbjct: 847 GPSGEAGT--------------------AGPPGTPGPQGLLGAPGILGLPGSRGERGLPG 886 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G GEPG +G G PG +G Sbjct: 887 VAG-------AVGEPGPLGIAGPPGARG 907 Score = 114 bits (285), Expect = 6e-25 Identities = 81/208 (38%), Positives = 99/208 (47%), Gaps = 21/208 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G GP GP G PG G+ G+ G PG G PG G G G G+ G PG G G+ GL+ Sbjct: 760 GAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLR 819 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL---PGPKGERGEK 1188 GP+G +G G G G GP GF G G G +G GPPGT GP GL PG G G + Sbjct: 820 GPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSR 879 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 GE + L + V + + PP + PG +GSPG PG Sbjct: 880 GE-RGLPGVAGAVGEPGPLG-------IAGPP----GARGPPGA--VGSPGVNG---APG 922 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 E GR G + G PG GQ G G++G Sbjct: 923 EAGRDG-NPGNDGPPGRDGQPGHKGERG 949 Score = 114 bits (285), Expect = 6e-25 Identities = 80/215 (37%), Positives = 97/215 (45%), Gaps = 22/215 (10%) Query: 997 GEMGSPPAAGFV----TLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASR 1052 GE G P AG V LG +A G R A + + D + + P R Sbjct: 880 GERGLPGVAGAVGEPGPLG-IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938 Query: 1053 DGET-------CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQG------FPGPRG 1099 DG+ P + + PGP GP GP G G G G G GPRG Sbjct: 939 DGQPGHKGERGYPGNIGPVGAAG-APGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRG 997 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPG---PPGPRGFQG 1156 P G +G +GD G PG +G G G+ G GLQG G+ G G G PG P GPRG G Sbjct: 998 PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAG 1057 Query: 1157 MAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 +G G G G PGTVGP G+ GP+G +G G P Sbjct: 1058 PSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPP 1092 Score = 112 bits (281), Expect = 2e-24 Identities = 78/224 (34%), Positives = 92/224 (41%), Gaps = 51/224 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGP------RGPPGVK---------GEKGDHGLPGL 1115 PGP GP G G PG G GE G PGP RGPPG G +G G PG Sbjct: 558 PGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGP 617 Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGL---EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 G+ G G+ G VG GP G GL G AG+PG G +G G+ G G G G G Sbjct: 618 DGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGA 677 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 G G PGP G G++GE + P P Sbjct: 678 PGAVGAPGPAGATGDRGEAGAAG-----------------------PAGP---------A 705 Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P GSPG R + G G G G+PGA G+ G+ G +G Sbjct: 706 GPRGSPGERGEVGPAGPNGFAG-PAGAAGQPGAKGERGAKGPKG 748 Score = 110 bits (275), Expect = 9e-24 Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 36/241 (14%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP------PGVKGEK 1107 G T P + + + PGP G +G G PG G PG G GP GP PG G Sbjct: 754 GPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPA 813 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGF---QGMA 1158 G GL G +G G G G VG GP KG G GTAG PG PGP+G G+ Sbjct: 814 GKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGIL 873 Query: 1159 GARGTSGERGPPGTVGPTGLPGP---KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHE 1215 G G+ GERG PG G G PGP G G +G P ++ + V+ A + D Sbjct: 874 GLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS--PGVNGAPGEAGRDGNPG 931 Query: 1216 NTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQ 1275 N P PG + G PG + + PG G G G PG G +G G+ Sbjct: 932 NDGP----------PGRD--GQPGHKGERGYPGNIGPVG----AAGAPGPHGPVGPAGKH 975 Query: 1276 G 1276 G Sbjct: 976 G 976 Score = 62.4 bits (150), Expect = 3e-09 Identities = 61/188 (32%), Positives = 74/188 (39%), Gaps = 45/188 (23%) Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT----------------VG 1174 +GP G RG G G PGPPG G G G G G GPPG G Sbjct: 32 KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91 Query: 1175 PTGL------------PGPKGERGEKGEPQSLATLYQLVSQ--ASHVSKFDSFHENTRPP 1220 P GL PGP+G +G GEP ++ A K +P Sbjct: 92 PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151 Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----------RGEPGAVGQM 1269 P E+ + G PGT +PG G RG L+G +GEPGA G+ Sbjct: 152 RP-GERGVVGPQGARGFPGTPG---LPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207 Query: 1270 GSPGQQGA 1277 G+PGQ GA Sbjct: 208 GTPGQTGA 215 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 144 bits (363), Expect = 5e-34 Identities = 94/237 (39%), Positives = 111/237 (46%), Gaps = 33/237 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P GE P ++ G GP GPPG G NG G GFPGP+GPPG G+ G Sbjct: 914 PTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973 Query: 1109 DHGLPGLQGHPGHQGI------PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAG 1159 G PG +G G QG PG VG QGP G G G G PGPPGP +G G+AG Sbjct: 974 LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 GT G+ GP G G G PG +G G++G P + L N P Sbjct: 1034 KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL--------------GLKGNEGP 1079 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P P PG P GSPG R A G G GR +G PG G+ G+PG++G Sbjct: 1080 PGP-------PG--PAGSPGERGPAGAAGPIGIPGRP-GPQGPPGPAGEKGAPGEKG 1126 Score = 142 bits (358), Expect = 2e-33 Identities = 97/250 (38%), Positives = 114/250 (45%), Gaps = 56/250 (22%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ---------------G 1093 PA GE PA + PG PGPQGPPG G G PGE+ G Sbjct: 1085 PAGSPGERGPAGAAG---PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG 1141 Query: 1094 FPGPR---GPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG 1150 PGP GPPG G+KG+ G PG +G G +G G G GP+G G G +G G PG Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201 Query: 1151 PRGFQGMAGARGTSGER---GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHV 1207 PRG QG+ G +G G R GPPG VG GLPGP GE+GE G+ + Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMG------------ 1249 Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAV 1266 PP P PG P G+PG PG G G E +GEPG Sbjct: 1250 -----------PPGP-------PGPRGPSGAPGADGPQGPPGGIGNPGAVGE-KGEPGEA 1290 Query: 1267 GQMGSPGQQG 1276 G+ G PG+ G Sbjct: 1291 GEPGLPGEGG 1300 Score = 140 bits (353), Expect = 8e-33 Identities = 88/218 (40%), Positives = 97/218 (44%), Gaps = 45/218 (20%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPG------------VKGEKGDHGLPGLQGH 1118 PGPPG GP G G G GE+G PGP GPPG KG+ G GLPG G Sbjct: 993 PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052 Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178 PG +G PG GL GP G GL+G G PGPPGP G G G G +G G PG GP G Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGP 1112 Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSP 1238 PGP GE+G GE P P L+ P+G P Sbjct: 1113 PGPAGEKGAPGE--------------------------KGPQGPAGRDGLQ---GPVGLP 1143 Query: 1239 GTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G PGE G G GEPG G G G+QG Sbjct: 1144 GPAGPVGPPGEDGDKGE----IGEPGQKGSKGDKGEQG 1177 Score = 139 bits (349), Expect = 2e-32 Identities = 85/209 (40%), Positives = 99/209 (47%), Gaps = 27/209 (12%) Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 S GPPGP+GPPG G G+PG GFPG GPPG G G G PG +G G G G Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376 Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187 G G G G G G PGP GP G QG GA+G +G GPPG GP GP+G G+ Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI---GPQGAPGK 1433 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247 G P L + P P+ EQ L P G PG +P Sbjct: 1434 PG-PDGLRGI----------------------PGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470 Query: 1248 GEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G G G E +G PG +G +G PG+QG Sbjct: 1471 GLKGDSGPKGE-KGHPGLIGLIGPPGEQG 1498 Score = 134 bits (336), Expect = 7e-31 Identities = 91/224 (40%), Positives = 105/224 (46%), Gaps = 24/224 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGP G GP G PG G PG G G GP G G +G+ G PG QG+PG QG+PG G Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737 Query: 1131 QGPKGMRGLEGTAGLPGPP---GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187 GP G +G G GLPG P GP G G G G G +GPPG GP G PGP+G +G Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA 797 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQKLE-----------PGT 1232 G T + K D + R PP P E E PG Sbjct: 798 DGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG- 856 Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PLG PG + K VPG G GR +G G++G G PG G Sbjct: 857 -PLGPPGEKGKLGVPGLPGYPGR----QGPKGSIGFPGFPGANG 895 Score = 132 bits (331), Expect = 3e-30 Identities = 90/220 (40%), Positives = 104/220 (47%), Gaps = 29/220 (13%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPG G PG PG+ G G QG GP GPPGV G +G G G G GH G PG G Sbjct: 966 PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGE 1025 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---------GPTGLPGP 1181 QG G+ G EGT G PGP G G G G RG G+RG PG V GP G PGP Sbjct: 1026 QGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGP 1085 Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----PLGS 1237 G GE+G P A + + PP P E K PG + P G Sbjct: 1086 AGSPGERG-PAGAAGPIGIPGRPGPQG----------PPGPAGE-KGAPGEKGPQGPAGR 1133 Query: 1238 PGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 G + +PG G G GE G G++G PGQ+G+ Sbjct: 1134 DGLQGPVGLPGPAGPVG----PPGEDGDKGEIGEPGQKGS 1169 Score = 131 bits (330), Expect = 4e-30 Identities = 97/256 (37%), Positives = 109/256 (42%), Gaps = 35/256 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 PA G+ P + PGP G G G G G PG G PG RGP G G G Sbjct: 1043 PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102 Query: 1109 DHGLPGLQGHP---GHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGP------------RG 1153 G PG QG P G +G PG G QGP G GL+G GLPGP GP G Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIG 1162 Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 G G++G GE+GPPG GP G G G G GEP Q K D Sbjct: 1163 EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------QQGLFGQKGDEG 1216 Query: 1214 HEN-TRPPMPILEQKL--EPGTE----------PLGSPGTRSKALVPGEWGRGGRHLEGR 1260 PP P+ Q L PG + P G PG R + PG G G G Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPP-GGI 1275 Query: 1261 GEPGAVGQMGSPGQQG 1276 G PGAVG+ G PG+ G Sbjct: 1276 GNPGAVGEKGEPGEAG 1291 Score = 128 bits (322), Expect = 3e-29 Identities = 86/215 (40%), Positives = 100/215 (46%), Gaps = 23/215 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG-- 1129 G PGP GPPG G+ G PG G+PG +GP KG G G PG G G +G PG+ G Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGP---KGSIGFPGFPGANGEKGGRGTPGKPGPR 909 Query: 1130 -LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 +GP G RG G G+ G PGP+G G G G GERGP G GPTG PGPKG G Sbjct: 910 GQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969 Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243 G+ H + F T PP P + Q T P+G G Sbjct: 970 GKD----------GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019 Query: 1244 ALVPGEWGRGG-RHLEG-RGEPGAVGQMGSPGQQG 1276 PGE G G EG +G+PG G G G G Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054 Score = 128 bits (321), Expect = 4e-29 Identities = 85/217 (39%), Positives = 101/217 (46%), Gaps = 33/217 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGH---PGHQGIPGRV 1128 GPPGP G PG GR G+ G +G PG GP G +G G GLPG +GH PG G PG Sbjct: 598 GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGF---------QGMAGARGTSGERGPPGTVGPTGLP 1179 G G +G G G GLPG PGPRG G G G G+ GP G VGP G P Sbjct: 658 GDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP 717 Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239 GP G++G G Q L + +P +P + PG + G PG Sbjct: 718 GPPGQQGNPG-AQGLPGPQGAIGPPGEKGPLG------KPGLPGM-----PGAD--GPPG 763 Query: 1240 TRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 K PGE G G+G PG G +G PG +G Sbjct: 764 HPGKEGPPGEKG-------GQGPPGPQGPIGYPGPRG 793 Score = 127 bits (320), Expect = 5e-29 Identities = 92/223 (41%), Positives = 103/223 (46%), Gaps = 52/223 (23%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGP GPQGP G PG +G GE PGPRG G+ G+KGD G G G PG G+ G G Sbjct: 1179 PGPTGPQGPIGQPGPSGADGE---PGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGP 1235 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG------------ERGPPGTVGPTGL 1178 G KG G G G PGPPGPRG G GA G G E+G PG G GL Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGL 1295 Query: 1179 PG---PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR-PPMPILEQKLEPGTE- 1233 PG P G +GE+GE K +S PP P K PG + Sbjct: 1296 PGEGGPPGPKGERGE------------------KGESGPSGAAGPPGP----KGPPGDDG 1333 Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P GSPG PG+ G GEPG GQ G PG +G Sbjct: 1334 PKGSPGPVG---FPGDPG-------PPGEPGPAGQDGPPGDKG 1366 Score = 127 bits (318), Expect = 9e-29 Identities = 86/207 (41%), Positives = 96/207 (46%), Gaps = 40/207 (19%) Query: 1075 GPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPK 1134 GP GP GL GR PGP GPPG G KG+ G G QG G QG PG G G + Sbjct: 559 GPAGPMGLTGR---------PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609 Query: 1135 GMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE- 1190 G G +G G+P GP G RGF G+AG G G RG PG GP G PG GERG+ GE Sbjct: 610 GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEV 669 Query: 1191 -PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 P+ L P +L K PG P G PG PG Sbjct: 670 GPRGL--------------------PGEPGPRGLLGPKGPPG--PPGPPGVTGMDGQPGP 707 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G G +GEPG GQ G+PG QG Sbjct: 708 KGNVG----PQGEPGPPGQQGNPGAQG 730 Score = 125 bits (315), Expect = 2e-28 Identities = 82/211 (38%), Positives = 99/211 (46%), Gaps = 39/211 (18%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PGP GPPG G G PG+ G P+GP GV+G G G PG +G G G G G Sbjct: 568 GRPGPVGPPGSGGLKGEPGDVG---PQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQT 624 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMA---GARGTSGERGPPGTVGPTGL---PGPKGER 1185 GPKG RG +G AGLPG G RG G + G G GERG G VGP GL PGP+G Sbjct: 625 GPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLL 684 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G KG P PP P ++ P G+ G + + Sbjct: 685 GPKGPP--------------------------GPPGPPGVTGMDGQPGPKGNVGPQGEPG 718 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG+ G G +G PG G +G PG++G Sbjct: 719 PPGQQGNPG----AQGLPGPQGAIGPPGEKG 745 Score = 121 bits (304), Expect = 4e-27 Identities = 86/226 (38%), Positives = 103/226 (45%), Gaps = 40/226 (17%) Query: 1071 PGPPGPQGP------PGLPGRNG------TPGEQGFPGPRGPPGVKGEKGDHGLPGLQGH 1118 PG PG QGP PG PG NG TPG+ G G RGP G +GE+G G+ G G Sbjct: 873 PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932 Query: 1119 PGHQG------IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 G+ G PG G GP+G G G G PGPPG G G G RG +G +G G Sbjct: 933 KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GP G+ GP+G GE G + + H PP P EQ L Sbjct: 993 PGPPGVVGPQGPTGETGP----------MGERGHPG----------PPGPPGEQGLPGLA 1032 Query: 1233 EPLGSPGTRSKALVPGEWGRGG-RHLEG-RGEPGAVGQMGSPGQQG 1276 G+ G A +PG+ G G R G RG PG VG +G G +G Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG 1078 Score = 121 bits (303), Expect = 5e-27 Identities = 86/236 (36%), Positives = 105/236 (44%), Gaps = 45/236 (19%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE---QGFPGPRGP------------------PGVKGEKGD 1109 PG PG GPPG PG+ G PGE QG PGP+GP G KGEKG+ Sbjct: 753 PGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE 812 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---------PGPRGFQGMAGA 1160 G PG +G G +G G +G GP+G G EG G GP PG +G G+ G Sbjct: 813 DGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL 872 Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP 1220 G G +GP G++G G PG GE+G +G P Q + + R P Sbjct: 873 PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQ---------RGPTGPRGERGP 923 Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 I +PG P G+ G A PGE G G G PG G G PG+ G Sbjct: 924 RGITG---KPG--PKGNSGGDGPAGPPGERGPNGPQ-GPTGFPGPKGPPGPPGKDG 973 Score = 120 bits (300), Expect = 1e-26 Identities = 61/119 (51%), Positives = 68/119 (57%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP G G+PG G G G PGP GPPG G G GL G G G +G PG +GL Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG 1189 GP G +G +G GLPGP G G +G G G SG GPPG G G PGPKG +G G Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG 1549 Score = 118 bits (296), Expect = 3e-26 Identities = 59/120 (49%), Positives = 67/120 (55%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP GPPG G G PG +G GP+G G G G G PG QG G +G+PG G Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 GPKG +G+ G +G GPPGP G G G +G G GP G G G PGP G G GE Sbjct: 1512 SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571 Score = 72.4 bits (176), Expect = 3e-12 Identities = 66/224 (29%), Positives = 88/224 (39%), Gaps = 14/224 (6%) Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPG----EQGFPGPRGPPGVKGEKGDHGLPGLQG 1117 +A + +S P PP +G L G ++ + P P + G+P Q Sbjct: 380 TADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQD 439 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTA----GLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 ++GI G G +G KG + G PGP GP G G G G +G+ G PG Sbjct: 440 TI-YEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGER 498 Query: 1174 GPTGLPGPKGERGEKGEPQSLATL-YQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GP G PG G G G P ++ L ++ SK IL+Q Sbjct: 499 GPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALR 558 Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P G G + G G GG +GEPG VG G G QG Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGL----KGEPGDVGPQGPRGVQG 598 Score = 32.7 bits (73), Expect = 2.3 Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 5/140 (3%) Query: 863 AMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMT 922 A S+ G + + KDAQL+ +YPA PE + L + + +AF + Sbjct: 63 ATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSI-LTTVKAKKGSQAFLVSIYN 121 Query: 923 AEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKV 982 + Q + L+ G+ S + + D + + G +H++ ++V + V Sbjct: 122 EQGIQQ---IGLELGR-SPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNV 177 Query: 983 RLYVDCRKVAERPLGEMGSP 1002 L +DC+K + L P Sbjct: 178 TLILDCKKKTTKFLDRSDHP 197 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 143 bits (361), Expect = 9e-34 Identities = 104/294 (35%), Positives = 117/294 (39%), Gaps = 71/294 (24%) Query: 1032 QIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETP---------------GPPGP 1076 +++C D DE + C +GE CP C SE+P GP GP Sbjct: 67 KVLCDDVICDETKNCPGAEVPEGECCPV----CPDGSESPTDQETTGVEGPKGDTGPRGP 122 Query: 1077 QGPPGLPGRNGTPGEQGFPGPRGP-------------------------------PGVKG 1105 +GP G PGR+G PG+ G PGP GP PG G Sbjct: 123 RGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG 182 Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 G GLPG G PG QG G G G G G G G PGPPG G G AG G G Sbjct: 183 PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 ERGPPG G GLPG G G KG S D + P P Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGH--------------RGFSGLDGAKGDAGPAGP--- 285 Query: 1226 QKLEPGTE-PLGSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQG 1276 K EPG+ G+PG +PGE GR G RG GA G G PG G Sbjct: 286 -KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG 338 Score = 140 bits (354), Expect = 6e-33 Identities = 100/249 (40%), Positives = 113/249 (45%), Gaps = 57/249 (22%) Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQG------------FP---------GPRGPPGVKGE 1106 PGPPGP G P G PG +G PG +G FP GP GPPG KG Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432 Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGP---------KGMRGLEGTAGLPGPPGPR----- 1152 G+ G PG +G G +G PG VG+QGP +G RG G GLPGPPG R Sbjct: 433 SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492 Query: 1153 ----GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 G G+AG +G +GERG PG GP G PG G GE G P + S Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP--- 549 Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQ 1268 T PP P Q PG P G PG R +A V G G G GEPG G+ Sbjct: 550 -----DGKTGPPGP-AGQDGRPG--PPGPPGARGQAGVMGFPGPKG----AAGEPGKAGE 597 Query: 1269 MGSPGQQGA 1277 G PG GA Sbjct: 598 RGVPGPPGA 606 Score = 139 bits (349), Expect = 2e-32 Identities = 95/232 (40%), Positives = 108/232 (46%), Gaps = 49/232 (21%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---------------GPRGPPGVKGEKGDHGLPGL 1115 PGP GP GP GLPG G PG QGF GPRGPPG G+ GD G G Sbjct: 178 PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237 Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP---PGT 1172 G PG +G P GP+G RGL GTAGLPG G RGF G+ GA+G +G GP PG+ Sbjct: 238 PGRPGERGPP------GPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291 Query: 1173 VGPTGLP---GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229 G G P GP+G GE+G P + + D PP P Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGA--------PGPAGARGNDGATGAAGPPGP------- 336 Query: 1230 PGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQQG 1276 T P G PG GE G +G R EG RGEPG G G+ G G Sbjct: 337 --TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386 Score = 135 bits (341), Expect = 2e-31 Identities = 88/213 (41%), Positives = 102/213 (47%), Gaps = 30/213 (14%) Query: 1071 PGPPGP------QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 PGPPGP +GP G G G PGE G PGP GP G KG G G G G PG QGI Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 G+ G+ G G RG G GLPGP G G QG +GA SGERGPPG +GP GL GP GE Sbjct: 955 AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA---SGERGPPGPMGPPGLAGPPGE 1011 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244 G +G P + + + S + + + T P G PG Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGE--------------------TGPAGPPGAPGAP 1051 Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG G G+ + RGE G G G G GA Sbjct: 1052 GAPGPVGPAGKSGD-RGETGPAGPAGPVGPVGA 1083 Score = 135 bits (340), Expect = 3e-31 Identities = 89/219 (40%), Positives = 101/219 (46%), Gaps = 20/219 (9%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPGR 1127 PG PGP G PG G +G GE+G PGP GPPG+ GE G G PG +G PG G PG Sbjct: 973 PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032 Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL---PGPKGE 1184 G +G G G G G PG PGP G G +G RG +G GP G VGP G GP+G Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP 1092 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244 RG+KGE T Q F PP EQ + P G G A Sbjct: 1093 RGDKGE-----TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147 Query: 1245 LVPGEWGRGGRHLEG-------RGEPGAVGQMGSPGQQG 1276 PG+ G G L G RG G G +G PG G Sbjct: 1148 GAPGKDGLNG--LPGPIGPPGPRGRTGDAGPVGPPGPPG 1184 Score = 129 bits (325), Expect = 1e-29 Identities = 89/228 (39%), Positives = 97/228 (42%), Gaps = 49/228 (21%) Query: 1072 GPPGPQGP------------------PGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDH 1110 GPPGP GP PG PG G PG QG PG RG PG KG++GD Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA 748 Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170 G G G PG G+ G G GP G G G G GP GP G G GA G GE GPP Sbjct: 749 GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230 G G G PG G+ G KGEP +K D+ PP P Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAG------------AKGDA-----GPPGP-------- 843 Query: 1231 GTEPLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 P G PG PG G RG G G PGA G++G PG G Sbjct: 844 -AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890 Score = 129 bits (324), Expect = 2e-29 Identities = 83/207 (40%), Positives = 95/207 (45%), Gaps = 3/207 (1%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP GP+GPPG PG+NG GE G PG G G G +G GLPG G PG +G G GL Sbjct: 215 GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G KG G G G PG PG G G G RG GERG PG GP G G G G G P Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251 + +K ++ + R + EPG P G G A PG G Sbjct: 335 GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG--PPGPAGAAGPAGNPGADG 392 Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 + G G PG G G PG +G S Sbjct: 393 QPGAK-GANGAPGIAGAPGFPGARGPS 418 Score = 129 bits (324), Expect = 2e-29 Identities = 89/230 (38%), Positives = 103/230 (44%), Gaps = 28/230 (12%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 GE+ P+ + + + PG G GPPG G G PG G PG +G PG G KGD G P Sbjct: 782 GESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP 841 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 G G G G G VG G KG RG G G G PG G G G G +G GPPG Sbjct: 842 GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA 901 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G GP+GE G G P + PP P E K PG + Sbjct: 902 GKEGGKGPRGETGPAGRPGEVGP--------------------PGPPGPAGE-KGSPGAD 940 Query: 1234 -PLGSPGTRSKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQGAS 1278 P G+PGT + G+ G G L G RG PG G G PG+QG S Sbjct: 941 GPAGAPGTPGPQGIAGQRGVVG--LPGQRGERGFPGLPGPSGEPGKQGPS 988 Score = 127 bits (320), Expect = 5e-29 Identities = 91/240 (37%), Positives = 104/240 (43%), Gaps = 39/240 (16%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 R G PA ++ GPPGP GPPG PG G GE G GPRG G +G +G Sbjct: 312 RPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRG 371 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168 + G PG G G G PG G G KG G G AG PG PG R G +G +G G G Sbjct: 372 EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR---GPSGPQGPGGPPG 428 Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-- 1226 P G G G PG KG+ G KGEP + PP P E+ Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGV--------------------QGPPGPAGEEGK 468 Query: 1227 ---KLEPGTEPL-------GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 + EPG L G PG+R G G G E RG PG G GSPG+ G Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE-RGSPGPAGPKGSPGEAG 527 Score = 127 bits (318), Expect = 9e-29 Identities = 100/296 (33%), Positives = 121/296 (40%), Gaps = 31/296 (10%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P GE G P + GF +A +GP + + A R G Sbjct: 483 PPGERGGPGSRGFPGADGVAGPKGPAGERGS------------PGPAGPKGSPGEAGRPG 530 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 E + S +PGP G GPPG G++G PG G PG RG GV G G G G Sbjct: 531 EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAG 590 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174 G G +G+PG G GP G G G G PGP GP G +G G G+ G +G PG G Sbjct: 591 EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650 Query: 1175 PTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE--PGT 1232 P PG G+ GE+G P L S A F PP P + PG Sbjct: 651 P---PGEAGKPGEQGVPGDLGA--PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705 Query: 1233 E----PLGSPGTRSKALVPGEWG----RGGRHLEG----RGEPGAVGQMGSPGQQG 1276 + G+PG PG G RG L G RG+ G G GSPG+ G Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761 Score = 124 bits (311), Expect = 6e-28 Identities = 90/242 (37%), Positives = 96/242 (39%), Gaps = 51/242 (21%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG------------- 1117 PG PG QG PGL G G G G PGP+G G G KG G PG G Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774 Query: 1118 --HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA------------RGT 1163 PG +G G G GP G RG G G PGPPGP GF G GA G Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA 834 Query: 1164 SGERGPPGTVGPTGLPGP---------KGERGEKGEPQSLATLYQLVSQASHVSKFDSFH 1214 G+ GPPG GP G PGP KG RG G P + A V Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG----FPGAAGRVGP-PGPS 889 Query: 1215 ENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQ 1274 N PP P E G P G G + PGE G G PG G+ GSPG Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGR---PGEVG-------PPGPPGPAGEKGSPGA 939 Query: 1275 QG 1276 G Sbjct: 940 DG 941 Score = 124 bits (310), Expect = 8e-28 Identities = 97/285 (34%), Positives = 116/285 (40%), Gaps = 73/285 (25%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLP------------------GRNGTPG 1090 PA +DG P + G PGP+G G P G++G G Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617 Query: 1091 EQGFPGPRGPPGVKGEKGDHGLPGLQ------------GHPGHQGIPGRVGLQGP---KG 1135 QG PGP GP G +GE+G G PG Q G PG QG+PG +G GP +G Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG 677 Query: 1136 MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------------------PGTVGPTG 1177 RG G G+ GPPGP G +G GA G G +G PG G G Sbjct: 678 ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGS 1237 LPGPKG+RG+ G A D T P P PG P G+ Sbjct: 738 LPGPKGDRGDAGP-----------KGADGSPGKDGVRGLTGPIGP-------PG--PAGA 777 Query: 1238 PGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGASTQ 1280 PG + ++ G G G R G RGEPG G G G GA Q Sbjct: 778 PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ 822 Score = 121 bits (303), Expect = 5e-27 Identities = 85/247 (34%), Positives = 97/247 (39%), Gaps = 42/247 (17%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL---PGRNGTPGEQGFPGPRGP----- 1100 P G PA + PGP G GPPG PG G PG G GP+GP Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512 Query: 1101 ----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG 1150 PG G G+ GLPG +G G G PG G GP G G +G G PGPPG Sbjct: 513 SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572 Query: 1151 PRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210 RG G+ G G G G PG G G+PGP G G G+ Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK-------------------- 612 Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270 D PP P P GSPG + G G G+ GE G G +G Sbjct: 613 DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK----PGEQGVPGDLG 668 Query: 1271 SPGQQGA 1277 +PG GA Sbjct: 669 APGPSGA 675 Score = 105 bits (262), Expect = 3e-22 Identities = 72/217 (33%), Positives = 83/217 (38%), Gaps = 72/217 (33%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P+ G+ P+ S GPPG GPPG GR G PG +G PG G PG KG++G Sbjct: 978 PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037 Query: 1109 DHGLPGLQGHPGHQGIPGRVGL------------------------------QGP----- 1133 + G G G PG G PG VG QGP Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKG 1097 Query: 1134 ----------KGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG--------- 1174 KG RG G G PGPPG G QG +GA G +G RGPPG+ G Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157 Query: 1175 ------------------PTGLPGPKGERGEKGEPQS 1193 P G PGP G G G P + Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194 Score = 92.4 bits (228), Expect = 2e-18 Identities = 61/152 (40%), Positives = 68/152 (44%), Gaps = 22/152 (14%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVK 1104 GET PA + GP GPQGP G G G G++G G P GPPG Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126 Query: 1105 GEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTS 1164 GE+G G G G +G PG G G G+ GL G GPPGPRG G AG G Sbjct: 1127 GEQGP---SGASGPAGPRGPPGSAGAPGKDGLNGLPGPI---GPPGPRGRTGDAGPVGPP 1180 Query: 1165 GERGPPGTVGPTG-------LPGPKGERGEKG 1189 G GPPG GP LP P E+ G Sbjct: 1181 GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212 Score = 52.0 bits (123), Expect = 4e-06 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 35/141 (24%) Query: 1138 GLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATL 1197 G+EG G GP GPRG G G G G+ G PG GP G PGP G G Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGN---------- 158 Query: 1198 YQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHL 1257 Q S+ + E + + + PG P+G G R PG Sbjct: 159 --FAPQLSY-----GYDEKSTGGISV------PG--PMGPSGPRGLPGPPG--------- 194 Query: 1258 EGRGEPGAVGQMGSPGQQGAS 1278 G G G G PG+ GAS Sbjct: 195 -APGPQGFQGPPGEPGEPGAS 214 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 143 bits (361), Expect = 9e-34 Identities = 93/227 (40%), Positives = 112/227 (49%), Gaps = 32/227 (14%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE---QGFPGPRGPPGVKGEKG------------DHGLPGL 1115 PGP G G PG+PG GTPGE QG PG RGPPG++G KG + G GL Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082 Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 +G PG QG PGR G QG G RG G+ G PG PGP G G G G G +GP G +GP Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE-- 1233 G GPKG G GEP L +A K D T ++ Q+ EPG E Sbjct: 1143 PGEMGPKGPPGAVGEP-------GLPGEAG--MKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193 Query: 1234 --PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 P+G G + PG G G +G+ G +G+ G PG G + Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGE----KGQEGLMGEDGPPGPPGVT 1236 Score = 140 bits (353), Expect = 8e-33 Identities = 93/233 (39%), Positives = 108/233 (46%), Gaps = 36/233 (15%) Query: 1071 PGPPGPQGPPG---LPGRNGT------PGEQGFPGPRG---PPGVKGEKGDHGLPGLQGH 1118 PGPPGP+G PG PG NG PG +G PGPRG P G +G G G PGL+G Sbjct: 903 PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962 Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178 PG +G PGR GL G KG G G G G G GF G+ G G GE+G G +GP G+ Sbjct: 963 PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022 Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----P 1234 PGPKG G G P + T + Q +R P + K G P Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGP---------PGSRGPPGMRGAKGRRGPRGPDGP 1073 Query: 1235 LGSPGTRSKALVPGEWGRGGR-----------HLEGRGEPGAVGQMGSPGQQG 1276 G G+R PG GR GR HL RG PG G G PG +G Sbjct: 1074 AGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG 1126 Score = 138 bits (347), Expect = 4e-32 Identities = 105/293 (35%), Positives = 123/293 (41%), Gaps = 48/293 (16%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P G+ G P G L + ARGPR + L D + DG Sbjct: 629 PKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDG 688 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 + S + PGPPG +G G PG G PGEQG PGP G PG KG G GLPG Sbjct: 689 AKGDMGLPGLSGN---PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPG 745 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---G 1171 G PG +G G +GL G G+ G +G GLPG PG RG GM G G GERGPP G Sbjct: 746 PVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDG 805 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 G GLPGP G G G+ L Sbjct: 806 NPGELGLPGPPGVPGLIGDLGVLG------------------------------------ 829 Query: 1232 TEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQG-ASTQGL 1282 P+G PG + + G G G L+G +GE G G G PG QG +QGL Sbjct: 830 --PIGYPGPKGMKGLMGSVGEPG--LKGDKGEQGVPGVSGDPGFQGDKGSQGL 878 Score = 137 bits (344), Expect = 9e-32 Identities = 82/218 (37%), Positives = 109/218 (50%), Gaps = 36/218 (16%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPG +GP G G G PG+ G+PG G G++G+ G G PG HPG +G PG G Sbjct: 1342 PGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPG---HPGPRGWPGPKGS 1398 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 +G +G +G +G AG PG G +G QG+ G RG G +G G GP GLPG G+ G++GE Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL----GSPGTRSKALV 1246 + PM ++ PG L G PG + ++ + Sbjct: 1459 QGD---------------------DGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGL 1497 Query: 1247 PGEWG-RGGRHLEGR-------GEPGAVGQMGSPGQQG 1276 PG+ G G R EGR GEPG+ GQ G G+ G Sbjct: 1498 PGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMG 1535 Score = 129 bits (325), Expect = 1e-29 Identities = 90/232 (38%), Positives = 107/232 (46%), Gaps = 24/232 (10%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPGLQ---GHPG 1120 S GP G QG G PGR G G QG PGPR G G++G G GLPG G G Sbjct: 1398 SKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG 1457 Query: 1121 HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPG 1180 QG G G GP G RG G AGLPG GP GF+G +G G G G GT G TGLPG Sbjct: 1458 EQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPG 1517 Query: 1181 PKGERGEKGEP--------QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG- 1231 +GE G KG+P +A L+ + F + R P ++ ++ G Sbjct: 1518 NQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG-FKGI-QGPRGPPGLMGKEGIVGP 1575 Query: 1232 ---TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280 P G PG + G+WG G RG PG G+ G PG G Q Sbjct: 1576 LGILGPSGLPGPKGDKGSRGDWGLQG----PRGPPGPRGRPGPPGPPGGPIQ 1623 Score = 128 bits (321), Expect = 4e-29 Identities = 86/232 (37%), Positives = 105/232 (45%), Gaps = 51/232 (21%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRG---------PPGVKGEKGDHGLPGLQGHPGHQ 1122 G PGP G PGL G G G G+PGP+G PG+KG+KG+ G+PG+ G PG Q Sbjct: 811 GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQ 870 Query: 1123 G---------IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 G PG G GP G G +G+ G PGPPGP GF G G G +G G G Sbjct: 871 GDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKP 930 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G GLPGP+G+ G +G+ + P P LE +PG + Sbjct: 931 GARGLPGPRGQLGPEGDEGPMGP----------------------PGAPGLEG--QPGRK 966 Query: 1234 PL-GSPGTRSKALVPGEWGRGGRHLEGR--------GEPGAVGQMGSPGQQG 1276 G PG PG+ GR G E GEPG VG+ G G G Sbjct: 967 GFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018 Score = 128 bits (321), Expect = 4e-29 Identities = 89/216 (41%), Positives = 103/216 (47%), Gaps = 42/216 (19%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G GPPG+PG G+ G G PG G PG E G G PG +G PG +G GR G + Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPG---EPGPQGPPGSRGPPGMRGAKGRRGPR 1068 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGF------QGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185 GP G G +G+ GL GPPGP+G QG+AG RG G RG PG GP+G PG KG Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244 GE G PQ P PI PG P G PG + Sbjct: 1129 GEPG-PQG-------------------------PQGPI----GPPGEMGPKGPPGAVGEP 1158 Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQGAS 1278 +PGE G G L GE G +GQ G PG +G S Sbjct: 1159 GLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDS 1194 Score = 126 bits (316), Expect = 2e-28 Identities = 87/227 (38%), Positives = 106/227 (46%), Gaps = 33/227 (14%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGP---------RGPPGVKGEKGDHGLPGLQGHPGH 1121 PG PGP GPPG G G PG QG GP +GPPG GE G G G++G G Sbjct: 1113 PGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP 1172 Query: 1122 QGIPGRVGLQGPKGMRGLEGTAGLPGP---------PGPRGFQGMAGARGTSGERGPPGT 1172 G PG GL G +G GLEG +G GP PGP G G G G GE GPPG Sbjct: 1173 LGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGP 1232 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 G TG+ GP+G+ G++GE + +K ++ M + PGT Sbjct: 1233 PGVTGVRGPEGKSGKQGE------------KGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280 Query: 1233 E-PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 P GS G+ PG G +G L G G G VG +G PG +G Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKG 1327 Score = 124 bits (312), Expect = 4e-28 Identities = 88/231 (38%), Positives = 106/231 (45%), Gaps = 57/231 (24%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPGHQGIP 1125 G GP GP GL G G PG G G +G G+ GE G G PG+ +G G QG Sbjct: 1192 GDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEK 1251 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT------------- 1172 GR G +G KG +G G G+PG PGP G G G+RG+ G G PG Sbjct: 1252 GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311 Query: 1173 -----VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQK 1227 VGP G PGPKGE+GE+GE D E PP P Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGE--------------------DGKAEG--PPGP----- 1344 Query: 1228 LEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276 PG P+G G R + PG G+ G ++G RG+PG GQ G PG +G Sbjct: 1345 --PGDRGPVGDRGDRGEPGDPGYPGQEG--VQGLRGKPGQQGQPGHPGPRG 1391 Score = 117 bits (292), Expect = 9e-26 Identities = 94/275 (34%), Positives = 116/275 (42%), Gaps = 69/275 (25%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL--------------- 1115 PG G GP G PG G PG QG PGP G PG KG +G GLPGL Sbjct: 720 PGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779 Query: 1116 ------------------QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---PGPRGF 1154 +G PG G PG +GL GP G+ GL G G+ GP PGP+G Sbjct: 780 PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839 Query: 1155 QGMAGA------RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 +G+ G+ +G GE+G PG G G G KG +G G P + L S Sbjct: 840 KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899 Query: 1209 -------KFDSFHENTRPP----------------MPILEQKLEP-GTE-PLGSPGTRSK 1243 + F + PP +P +L P G E P+G PG Sbjct: 900 IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959 Query: 1244 ALVPGEWGRGGR-HLEG-RGEPGAVGQMGSPGQQG 1276 PG G GR L+G +GEPG G+ G G+QG Sbjct: 960 EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQG 994 Score = 114 bits (284), Expect = 8e-25 Identities = 80/228 (35%), Positives = 100/228 (43%), Gaps = 18/228 (7%) Query: 990 KVAERPLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELP 1049 K AE P G+ G A G + L GPR L+ + D + Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458 Query: 1050 ASRDGETCPAFVSACSCSSETPGPPGPQGPPGL------------PGRNGTPGEQGFPGP 1097 DG+ P + + G PG QGPPG PG+ GT G G PG Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGN 1518 Query: 1098 RGPPGVKGEKGDHG---LPGLQGHPGHQGIPGRVG---LQGPKGMRGLEGTAGLPGPPGP 1151 +G PG KG+ GD G PG+ G G +G PG +G +QGP+G GL G G+ GP G Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578 Query: 1152 RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQ 1199 G G+ G +G G RG G GP G PGP+G G G P L Q Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQ 1626 Score = 111 bits (278), Expect = 4e-24 Identities = 86/261 (32%), Positives = 103/261 (39%), Gaps = 64/261 (24%) Query: 1071 PGPPGP---------------------------------QGPPGLPGRNGTPGEQGFPGP 1097 PGPPG G PG PG GTPG +G G Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289 Query: 1098 RGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEG----TAGLPGPPGPR- 1152 GP G G G G PGL G+ GH+GI G +G GPKG +G +G G PGPPG R Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349 Query: 1153 -----------------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLA 1195 G +G+ G RG G++G PG GP G PGPKG +G +G Sbjct: 1350 PVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK-- 1407 Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255 Q + A P + Q LE P G PG +A GE G G Sbjct: 1408 ---QGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDG- 1463 Query: 1256 HLEGRGEPGAVGQMGSPGQQG 1276 G G G+ G+PG G Sbjct: 1464 ---DPGPMGPAGKRGNPGVAG 1481 Score = 94.4 bits (233), Expect = 6e-19 Identities = 74/206 (35%), Positives = 91/206 (44%), Gaps = 35/206 (16%) Query: 1090 GEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 G FP GPPG KGD GLPG G PG GIP G +GP+G G G GLPGPP Sbjct: 616 GSTPFPLLMGPPGP---KGDCGLPGPPGLPGLPGIP---GARGPRGPPGPYGNPGLPGPP 669 Query: 1150 GPR---------------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSL 1194 G + G +G G G SG GPPG G G PGP G GE+G+P Sbjct: 670 GAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPG-- 727 Query: 1195 ATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL----GSPGTRSKALVPGEW 1250 + S +K + P+ K G L G PG+ + +PG Sbjct: 728 -------PEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVP 780 Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G+ G+ + G PG G+ G PG G Sbjct: 781 GKRGK-MGMPGFPGVFGERGPPGLDG 805 Score = 32.0 bits (71), Expect = 3.9 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 19/80 (23%) Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-------R 1260 S + FH P P+L +G PG + +PG G G L G R Sbjct: 607 SGYSIFHLAGSTPFPLL----------MGPPGPKGDCGLPGPPGLPG--LPGIPGARGPR 654 Query: 1261 GEPGAVGQMGSPGQQGASTQ 1280 G PG G G PG GA Q Sbjct: 655 GPPGPYGNPGLPGPPGAKGQ 674 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 142 bits (359), Expect = 2e-33 Identities = 96/220 (43%), Positives = 106/220 (48%), Gaps = 38/220 (17%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP---GLQGHPGHQGIPGR 1127 PGPPGP GPPG PG++G GE G PG GPPG KG G G P GL G PG G+ GR Sbjct: 31 PGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGR 90 Query: 1128 VGLQGPKGMRGLEGTAGLPGP--------PGPRGFQGMAGARGTSGERGPPGTVGPTGLP 1179 G GPKG G G+ G PGP PGP G G++G G G RGPPG G GLP Sbjct: 91 DGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLP 150 Query: 1180 GPKGERGEKGEPQSL---ATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLG 1236 GP G G G P L AT Q S PP P PG P G Sbjct: 151 GPPGPPGPPGHPGVLPEGATDLQCPSIC--------------PPGP-------PG--PPG 187 Query: 1237 SPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG + GE G G+ E +G+PG G G PG G Sbjct: 188 MPGFKGPTGYKGEQGEVGKDGE-KGDPGPPGPAGLPGSVG 226 Score = 138 bits (348), Expect = 3e-32 Identities = 94/237 (39%), Positives = 114/237 (48%), Gaps = 38/237 (16%) Query: 1071 PGPPGPQGPPGLPG---------------RNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115 PGPPGP GPPG PG G PG G PG +GP G KGE+G+ G G Sbjct: 150 PGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGE 209 Query: 1116 QGHPGHQG---IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 +G PG G +PG VGLQGP+G+RGL G G PG GP GF+G G G G+ G G Sbjct: 210 KGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE 269 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE-QKLEPG 1231 GP G GPKG+ G G P+ + + K + + +P L+ QK E G Sbjct: 270 RGPEGFRGPKGDLGRPG-PKGTPGVAGPSGEPGMPGK------DGQNGVPGLDGQKGEAG 322 Query: 1232 TE-------PLGSPGTRSKALVPGEWGRGGRHLE-----GRGEPGAVGQMGSPGQQG 1276 P G PG +A GE G GR E GEPG G G PG++G Sbjct: 323 RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERG 379 Score = 124 bits (312), Expect = 4e-28 Identities = 91/252 (36%), Positives = 110/252 (43%), Gaps = 39/252 (15%) Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRN---GTPGEQGFPGPRGPP 1101 LP CP+ C PGPPG +GP G G G GE+G PGP GP Sbjct: 165 LPEGATDLQCPSI-----CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPA 219 Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIP---GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158 G+ G G G GL+G PG G P G +G +GP G+ G G AG G GP GF+G Sbjct: 220 GLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPK 279 Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218 G G G +G PG GP+G PG G+ G+ G P L Q + + E Sbjct: 280 GDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP-------GLDGQKGEAGRNGAPGEKGP 332 Query: 1219 PPMPILE-------QKLEPG-------TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPG 1264 +P L +K E G P G PG A +PGE G G RG G Sbjct: 333 NGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH----RGSAG 388 Query: 1265 AVGQMGSPGQQG 1276 A+G G PG G Sbjct: 389 ALGPQGPPGAPG 400 Score = 120 bits (300), Expect = 1e-26 Identities = 87/233 (37%), Positives = 109/233 (46%), Gaps = 40/233 (17%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G GP G PG+PG G PGE+G G RG G G +G G PG++G G +G G GL Sbjct: 358 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP 417 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 GP+G+RG G G G GP+G QG+AG+ G G++ G +GP+GL GPKGE G +GE Sbjct: 418 GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDK---GELGPSGLVGPKGESGSRGEL 474 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE--PG-TEPLGSPGTRS------ 1242 T Q + S V PP P+ Q + PG T G PG + Sbjct: 475 GPKGT--QGPNGTSGVQGVPG------PPGPLGLQGVPGVPGITGKPGVPGKEASEQRIR 526 Query: 1243 -------------------KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 K L PG GR G G PG G +G PG +G Sbjct: 527 ELCGGMISEQIAQLAAHLRKPLAPGSIGRPG-PAGPPGPPGPPGSIGHPGARG 578 Score = 119 bits (299), Expect = 1e-26 Identities = 87/234 (37%), Positives = 102/234 (43%), Gaps = 48/234 (20%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPG------------PRGPPGVKGEKGDHGLP----- 1113 PG PGP GP G PG+ G PGE G PG P GP G GE+G G P Sbjct: 55 PGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL 114 Query: 1114 ---GLQGHPGHQGI---PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER 1167 GL G PG G+ PG +GL+GP G GL G G PGPPGP G G+ T + Sbjct: 115 GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQC 174 Query: 1168 G---PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 PPG GP G+PG KG G KGE + D + PP P Sbjct: 175 PSICPPGPPGPPGMPGFKGPTGYKGEQGEVGK--------------DGEKGDPGPPGP-- 218 Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH--LEGRGEPGAVGQMGSPGQQG 1276 PG+ +G G R +PG G G + RG PG G G G +G Sbjct: 219 --AGLPGS--VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG 268 Score = 118 bits (295), Expect = 4e-26 Identities = 88/239 (36%), Positives = 113/239 (47%), Gaps = 25/239 (10%) Query: 1070 TPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPG 1120 TPG GP G PG+PG+ NG PG G G G G GEKG +GLPGL +G G Sbjct: 290 TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349 Query: 1121 HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---------G 1171 +G G +G GP G G+ G AG+PG G G +G AGA G G G P G Sbjct: 350 ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 ++G GLPGP+G RG+ G+ Q S + P ++ K E G Sbjct: 410 SMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESG 469 Query: 1232 TE----PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGASTQGLWE 1284 + P G+ G + V G G G L+G G PG G+ G PG++ AS Q + E Sbjct: 470 SRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE-ASEQRIRE 527 Score = 117 bits (293), Expect = 7e-26 Identities = 81/213 (38%), Positives = 102/213 (47%), Gaps = 22/213 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGD---HGLPGLQGHPGHQGIPGRV 1128 G PGP+G PG+ G +G PG G G G PG+ G+KG+ +G PG +G G G+PGR Sbjct: 283 GRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRA 342 Query: 1129 GLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185 G +G KG RG G G GP PG G GM G RG +G RG G +GP G PG G R Sbjct: 343 GSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVR 402 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G+ S+ Q D R P P G G Sbjct: 403 GFQGQKGSMGDPGLPGPQGLRGDVGD------RGP--------GGAAGPKGDQGIAGSDG 448 Query: 1246 VPGEWGR-GGRHLEG-RGEPGAVGQMGSPGQQG 1276 +PG+ G G L G +GE G+ G++G G QG Sbjct: 449 LPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481 Score = 117 bits (292), Expect = 9e-26 Identities = 82/226 (36%), Positives = 102/226 (45%), Gaps = 20/226 (8%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP GP G PG+ G G G G PG GP G++G+ GD G G G G QGI G GL Sbjct: 391 GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP 450 Query: 1132 G------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185 G P G+ G +G +G G GP+G QG G G G GPPG +G G+PG G Sbjct: 451 GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT-------EPLGSP 1238 G+ G P A+ ++ + E L + L PG+ P G P Sbjct: 511 GKPGVPGKEASEQRIRELCGGM-----ISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565 Query: 1239 GTRSKALVPGEWGRGG-RHLEGR-GEPGAVGQMGSPGQQGASTQGL 1282 G PG G G R G G+PG G G G +GA+ GL Sbjct: 566 GPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL 611 Score = 105 bits (262), Expect = 3e-22 Identities = 80/241 (33%), Positives = 100/241 (41%), Gaps = 60/241 (24%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 S PG G GP GL G G G +G GP+G G G G G+PG G G QG+PG Sbjct: 446 SDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPG 505 Query: 1127 RVGLQGPKGMRGLE-------------------------------GTAGLPGPPGPRGFQ 1155 G+ G G+ G E G+ G PGP GP G Sbjct: 506 VPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565 Query: 1156 GMAGARGTSGERGPPGTVGPTGL---PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDS 1212 G G+ G G RGPPG GPTG PGP+G +G++G+ + + + D Sbjct: 566 GPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD------------KGAAGAGLDG 613 Query: 1213 FHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSP 1272 + P P + PGT G G PGE G G G PGA+G G+P Sbjct: 614 PEGDQGPQGP----QGVPGTSKDGQDG------APGEPGPPG----DPGLPGAIGAQGTP 659 Query: 1273 G 1273 G Sbjct: 660 G 660 Score = 91.7 bits (226), Expect = 4e-18 Identities = 57/131 (43%), Positives = 69/131 (52%), Gaps = 11/131 (8%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQG--IPGRV 1128 PGP GP GPPG PG G PG +G PG RGP G G+ G G G +G G G + G Sbjct: 556 PGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615 Query: 1129 GLQGPKGMRGLEGTA-----GLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP-K 1182 G QGP+G +G+ GT+ G PG PGP G G+ GA G +G PG + G Sbjct: 616 GDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGA---QGTPGICDTSACQGAVL 672 Query: 1183 GERGEKGEPQS 1193 G GEK +S Sbjct: 673 GGVGEKSGSRS 683 Score = 80.9 bits (198), Expect = 7e-15 Identities = 64/178 (35%), Positives = 71/178 (39%), Gaps = 45/178 (25%) Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170 GLPG G PG G PG+ G+ G G GLPGPPGP+G G G G +G G P Sbjct: 29 GLPGPPGPPGPPGKPGQDGIDGEAG------PPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230 G G TG GP G +G GE SL PP P P Sbjct: 83 GVDGLTGRDGPPGPKGAPGERGSLG-----------------------PPGP-------P 112 Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEGR-------GEPGAVGQMGSPGQQGASTQG 1281 G G PG +A V G GG L G G PG G G PG G +G Sbjct: 113 GLGGKGLPGPPGEAGVSGP--PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG 168 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 142 bits (358), Expect = 2e-33 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122 GPPGP G PG PG+ G+PG G G RG PG KGE+GD G PG +G PG + Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG G +G GM GL+G GLP GPPGPRG G G G G RG PG++G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 G+PG KG+RG G P L ++ L + E TRP P Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067 Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 P G PG GE G+ G HL G GA G GSPG G Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113 Score = 138 bits (347), Expect = 4e-32 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 PGPPGP G PGLPG G GE G P GP GP G G G GLPG G G G Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177 G GL GP G+RG G G PG PGP RG QG G G +GE+G G + GP G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236 PG +G +G++G P + + + + E P P L + PG T G Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242 Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282 PG+R PG G G H+ G +G PG G MG PG+ GA T GL Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302 Score = 129 bits (325), Expect = 1e-29 Identities = 85/210 (40%), Positives = 99/210 (47%), Gaps = 31/210 (14%) Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126 PGPPG G PG G G PG +G PG GPPG G G G G GHPG +G PG Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G GT GLPGP G GFQG G +G G G G++GP G GPKG G Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246 +G+P +L K S + PP GT G PG + + Sbjct: 1344 VRGDPGTL--------------KIISLPGSPGPP----------GTP--GEPGMQGEPGP 1377 Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G G RG+PG G+ G+PG G Sbjct: 1378 PGPPGNLGP-CGPRGKPGKDGKPGTPGPAG 1406 Score = 127 bits (320), Expect = 5e-29 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%) Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107 S S+ PGPPGP GPPG PG G P G+ G PGP G PG+ G K Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708 Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159 GD G PG + G G G+PG+ GL G KG + G G PG PG RG G G Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203 G G G PGT G GL GP+G+ G+ G P Q L L L Q Sbjct: 769 EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828 Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263 K + P +P L++ PG GSPG +PG G G L RG P Sbjct: 829 QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876 Query: 1264 GAVGQMGSPGQQG 1276 G G +G PG+ G Sbjct: 877 GNPGILGPPGEDG 889 Score = 123 bits (309), Expect = 1e-27 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%) Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109 PGP GP+G PGLPG +G+PG G PG GP PG G KG+ Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161 G PGL G G+ GIPG GL+G KG E G GLPG PGP+G G G Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191 Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221 G G GPPG G G GP+G +G GE +++ T PP Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239 Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 P PGT + G ++ + GE G G GEPG G G PG+ S +G Sbjct: 240 P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288 Score = 121 bits (304), Expect = 4e-27 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090 P G P S PG PGP +GPPGLPG G+PG Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123 G PGPRG PG +G KGD G PG G PG +G Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157 IPG+ G +GP G RG G G PGPPG G +G Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269 Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196 G+ G G +GPPGT G GLPGP+G+ +GEKG P L + Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256 + PP PI K PG G PGT +PG G G Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365 Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276 GEPG G+ G PG G Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382 Score = 120 bits (300), Expect = 1e-26 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106 GPPG +GPPGLPG G+PG G PGPRG PG +G Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164 KGD G PG G PG +G G G +GP G+ G G GLPG PG G +G G+RG+ Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 G GPPG G + + G KG++G G P + P Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285 Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG LG+PGT +PG G G +G PG G+ G+PG G+ Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329 Score = 120 bits (300), Expect = 1e-26 Identities = 69/147 (46%), Positives = 78/147 (53%), Gaps = 24/147 (16%) Query: 1072 GPPGPQGPPGL------PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 G PGP+GPPG PGR G PG G PGPRG PG +G G G G G G G P Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333 Query: 1126 GRVGLQGPKGMRGLEGT---AGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP------- 1175 G +G +GP G+RG GT LPG PGP G G G +G G GPPG +GP Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 1176 -----TGLPGP---KGERGEKGEPQSL 1194 G PGP KG +G KGEP+SL Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPESL 1420 Score = 119 bits (298), Expect = 2e-26 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%) Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 PA C C + G G +G G PG G+PG++GF GP G PG +G KG GLP Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 GL G G +GI G L G G GL GT G GP G G G +G++G G G PGT+ Sbjct: 85 GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G+PG G +G+KG P +K D P + PG Sbjct: 142 GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192 Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276 P+G PG PG G G R + +GE G G G PG G Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 119 bits (298), Expect = 2e-26 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118 PG PGPQGPPG+PG G G+ G PGP G PG+ G KGD G PG +G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174 G G+PG+ GL G KG + G G PG PG RG G G G G G PGT G Sbjct: 724 GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783 Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218 GL GP+G+ G+ G P Q L L L Q K + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840 Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260 P +P L++ PG PLG PG PGE G G G Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280 G PG GQ GSPG G Q Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 117 bits (293), Expect = 7e-26 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%) Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106 C+ S PG PGP GPPG + R G PG+ G PG G PG+ KGE Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 G GLPGL G G +GIPGR G G KG G G GLPG PG G QG G +G G Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 E RG PG G G+PG G +G G LA + Q Sbjct: 542 ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268 PP +PG+ GSPG A PG +G L+G +G PGA G Sbjct: 597 ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1269 MGSPGQQG 1276 G G +G Sbjct: 639 PGEAGPRG 646 Score = 117 bits (293), Expect = 7e-26 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%) Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102 C+ PGPPG G PGL PG G PG GFPG +G PG Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158 +KGEKG+ G G+ G PG +G PGR GL G+ G G GLPGP G G Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592 Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218 G +G G+ G PG+ GP G GP G G +GEP T Q V A Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649 Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274 P+ PG P G PG + +PG G+ G L G GEPG +G G PG Sbjct: 650 VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1275 QG 1276 +G Sbjct: 708 KG 709 Score = 116 bits (291), Expect = 1e-25 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%) Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114 S +PGP GP GPPG PG GT G G PGP G G +GE G G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662 Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 GHPG QG PG GL GP G G+ G G PGPPGP+G QG G T G Sbjct: 663 PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 G PG +G GLPG G G KGEP + Sbjct: 719 SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274 PGT G PG R + GE G G L+G RG+PG G G G Sbjct: 748 MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Query: 1275 QGASTQG 1281 G +G Sbjct: 806 PGRCIEG 812 Score = 116 bits (290), Expect = 2e-25 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%) Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125 G PG G PG PG G+PG G PGP GPPG KG GDHGLPG G PG IP Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463 Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 G + GPKG GL G GLPG PG G +G+ G +G +G +G PG+ G TG Sbjct: 464 G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236 LPG G G +G+P + + V +P L+ PGT + G Sbjct: 521 LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578 Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282 PG + + + GE G G + G PG G G PG GL Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 115 bits (288), Expect = 3e-25 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107 G P+ +S PG G G PG G G PG +G PGP GPPG +G+ Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166 G G P G PG +GIPG +G G G +G GT G PG G G G+ G +G GE Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056 Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 GPPG G GLPG G++GE G+P P Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274 P + E GSPG K G+ G +G + L G RG PG G GSPG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 1275 QG 1276 G Sbjct: 1151 MG 1152 Score = 113 bits (283), Expect = 1e-24 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%) Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099 PGPPG QGPPG LPG NG G+QG FPG G Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144 PG+ G +G+ G G +G+PG+ GI PG +G GP G G G G Sbjct: 857 SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189 PG PG +G +G GA+G G++G PG G G PG KG RG G Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 P L L L A P P L + + +G PG++ K G Sbjct: 977 MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 GR GR G PG G G G+ G S Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059 Score = 113 bits (282), Expect = 1e-24 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122 G PG G PG PG G G +GFPG G G+KG+KGD G PG +G G + Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356 Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175 G PG G +G +G +G G G+PG PG RG G G +G+ GERG PG +G Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G PG G G G P PP I+ +K PG Sbjct: 417 PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451 Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278 G PG +PG G G ++ G G PG G G PG+QGA+ Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Score = 112 bits (281), Expect = 2e-24 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%) Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116 PG PGPQG PPG PG G PG GF GPRGP G GE KG+ G+ GL Sbjct: 176 PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235 Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165 G PG G V L GP KG +G +G G PGPPGP G G + GA G G Sbjct: 236 GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 +G PG G G PG +G +G +G P + K D R P + Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 E G E G+PG PG G RG G G G PG G+S GL Sbjct: 349 TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390 Score = 112 bits (281), Expect = 2e-24 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%) Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085 TPGPPGP+ GPPG+PG Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417 Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136 G+PG G PGP GPPG KG GDHGLPG G P GIP G+ GPKG Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471 Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GL G GLPG PG G +G+ G +G +G +G PG+ G TGLPG G G + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247 G+P + + V P P L + +PG + L G PGT +P Sbjct: 532 GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580 Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276 G +G L G +G+ G G GSPG G Sbjct: 581 GP--KGELALSGEKGDQGPPGDPGSPGSPG 608 Score = 107 bits (268), Expect = 6e-23 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102 PG PGP GPPG PG G PG +G GP GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142 +KGEKGD G G G PG G+PG GLQG G G+ G Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307 Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187 G G G RGF G+ G G G++ GPPG GPT G PGP G RG Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247 +G PQ + P +P PG G+PG Sbjct: 368 RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403 Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276 GE GR G+ G G PG G G PG G Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Score = 102 bits (255), Expect = 2e-21 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%) Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102 G T P V CS G G QG PGLPG G PG G G +G P Sbjct: 112 GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167 Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156 KG+ G G PG QG PG G PG VG GP G G G G GP G G +G Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227 Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 G +G +G GPPGTV GP T L G KG++G GEP Sbjct: 228 ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274 Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267 + P +K PG L G PG PG G G RG PG +G Sbjct: 275 ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324 Query: 1268 QMGSPGQQG 1276 + G GQ+G Sbjct: 325 EDGIKGQKG 333 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 142 bits (358), Expect = 2e-33 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122 GPPGP G PG PG+ G+PG G G RG PG KGE+GD G PG +G PG + Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG G +G GM GL+G GLP GPPGPRG G G G G RG PG++G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 G+PG KG+RG G P L ++ L + E TRP P Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067 Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 P G PG GE G+ G HL G GA G GSPG G Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113 Score = 138 bits (347), Expect = 4e-32 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 PGPPGP G PGLPG G GE G P GP GP G G G GLPG G G G Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177 G GL GP G+RG G G PG PGP RG QG G G +GE+G G + GP G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236 PG +G +G++G P + + + + E P P L + PG T G Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242 Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282 PG+R PG G G H+ G +G PG G MG PG+ GA T GL Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302 Score = 135 bits (340), Expect = 3e-31 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%) Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126 PGPPG G PG G G PG +G PG GPPG G G G G GHPG +G PG Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G GT GLPGP G GFQG G +G G G G++GP G GPKG G Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 +G+P +L + S + + PP P L P P G PG K Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G G + +GEPG G G PG +G Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430 Score = 127 bits (320), Expect = 5e-29 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%) Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107 S S+ PGPPGP GPPG PG G P G+ G PGP G PG+ G K Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708 Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159 GD G PG + G G G+PG+ GL G KG + G G PG PG RG G G Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203 G G G PGT G GL GP+G+ G+ G P Q L L L Q Sbjct: 769 EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828 Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263 K + P +P L++ PG GSPG +PG G G L RG P Sbjct: 829 QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876 Query: 1264 GAVGQMGSPGQQG 1276 G G +G PG+ G Sbjct: 877 GNPGILGPPGEDG 889 Score = 123 bits (309), Expect = 1e-27 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%) Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109 PGP GP+G PGLPG +G+PG G PG GP PG G KG+ Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161 G PGL G G+ GIPG GL+G KG E G GLPG PGP+G G G Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191 Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221 G G GPPG G G GP+G +G GE +++ T PP Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239 Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 P PGT + G ++ + GE G G GEPG G G PG+ S +G Sbjct: 240 P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288 Score = 121 bits (304), Expect = 4e-27 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090 P G P S PG PGP +GPPGLPG G+PG Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123 G PGPRG PG +G KGD G PG G PG +G Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157 IPG+ G +GP G RG G G PGPPG G +G Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269 Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196 G+ G G +GPPGT G GLPGP+G+ +GEKG P L + Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256 + PP PI K PG G PGT +PG G G Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365 Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276 GEPG G+ G PG G Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382 Score = 120 bits (300), Expect = 1e-26 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106 GPPG +GPPGLPG G+PG G PGPRG PG +G Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164 KGD G PG G PG +G G G +GP G+ G G GLPG PG G +G G+RG+ Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 G GPPG G + + G KG++G G P + P Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285 Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG LG+PGT +PG G G +G PG G+ G+PG G+ Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329 Score = 119 bits (299), Expect = 1e-26 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117 TPG PGP+G PG G G GE+G P GP+GPPGV+G+ G + L G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358 Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171 PG G PG G+Q GP G G G G PG G G G AG +G G +G PG Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 G GLPG KG+RG+ G P + T + ++ S + S E T P Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466 Score = 119 bits (298), Expect = 2e-26 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%) Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 PA C C + G G +G G PG G+PG++GF GP G PG +G KG GLP Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 GL G G +GI G L G G GL GT G GP G G G +G++G G G PGT+ Sbjct: 85 GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G+PG G +G+KG P +K D P + PG Sbjct: 142 GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192 Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276 P+G PG PG G G R + +GE G G G PG G Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 119 bits (298), Expect = 2e-26 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118 PG PGPQGPPG+PG G G+ G PGP G PG+ G KGD G PG +G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174 G G+PG+ GL G KG + G G PG PG RG G G G G G PGT G Sbjct: 724 GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783 Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218 GL GP+G+ G+ G P Q L L L Q K + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840 Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260 P +P L++ PG PLG PG PGE G G G Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280 G PG GQ GSPG G Q Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 117 bits (293), Expect = 7e-26 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%) Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106 C+ S PG PGP GPPG + R G PG+ G PG G PG+ KGE Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 G GLPGL G G +GIPGR G G KG G G GLPG PG G QG G +G G Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 E RG PG G G+PG G +G G LA + Q Sbjct: 542 ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268 PP +PG+ GSPG A PG +G L+G +G PGA G Sbjct: 597 ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1269 MGSPGQQG 1276 G G +G Sbjct: 639 PGEAGPRG 646 Score = 117 bits (293), Expect = 7e-26 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%) Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102 C+ PGPPG G PGL PG G PG GFPG +G PG Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158 +KGEKG+ G G+ G PG +G PGR GL G+ G G GLPGP G G Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592 Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218 G +G G+ G PG+ GP G GP G G +GEP T Q V A Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649 Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274 P+ PG P G PG + +PG G+ G L G GEPG +G G PG Sbjct: 650 VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1275 QG 1276 +G Sbjct: 708 KG 709 Score = 116 bits (291), Expect = 1e-25 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%) Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114 S +PGP GP GPPG PG GT G G PGP G G +GE G G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662 Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 GHPG QG PG GL GP G G+ G G PGPPGP+G QG G T G Sbjct: 663 PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 G PG +G GLPG G G KGEP + Sbjct: 719 SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274 PGT G PG R + GE G G L+G RG+PG G G G Sbjct: 748 MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Query: 1275 QGASTQG 1281 G +G Sbjct: 806 PGRCIEG 812 Score = 116 bits (290), Expect = 2e-25 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%) Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125 G PG G PG PG G+PG G PGP GPPG KG GDHGLPG G PG IP Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463 Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 G + GPKG GL G GLPG PG G +G+ G +G +G +G PG+ G TG Sbjct: 464 G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236 LPG G G +G+P + + V +P L+ PGT + G Sbjct: 521 LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578 Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282 PG + + + GE G G + G PG G G PG GL Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 115 bits (288), Expect = 3e-25 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107 G P+ +S PG G G PG G G PG +G PGP GPPG +G+ Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166 G G P G PG +GIPG +G G G +G GT G PG G G G+ G +G GE Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056 Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 GPPG G GLPG G++GE G+P P Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274 P + E GSPG K G+ G +G + L G RG PG G GSPG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 1275 QG 1276 G Sbjct: 1151 MG 1152 Score = 113 bits (283), Expect = 1e-24 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%) Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099 PGPPG QGPPG LPG NG G+QG FPG G Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144 PG+ G +G+ G G +G+PG+ GI PG +G GP G G G G Sbjct: 857 SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189 PG PG +G +G GA+G G++G PG G G PG KG RG G Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 P L L L A P P L + + +G PG++ K G Sbjct: 977 MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 GR GR G PG G G G+ G S Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059 Score = 113 bits (282), Expect = 1e-24 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122 G PG G PG PG G G +GFPG G G+KG+KGD G PG +G G + Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356 Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175 G PG G +G +G +G G G+PG PG RG G G +G+ GERG PG +G Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G PG G G G P PP I+ +K PG Sbjct: 417 PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451 Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278 G PG +PG G G ++ G G PG G G PG+QGA+ Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Score = 112 bits (281), Expect = 2e-24 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%) Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116 PG PGPQG PPG PG G PG GF GPRGP G GE KG+ G+ GL Sbjct: 176 PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235 Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165 G PG G V L GP KG +G +G G PGPPGP G G + GA G G Sbjct: 236 GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 +G PG G G PG +G +G +G P + K D R P + Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 E G E G+PG PG G RG G G G PG G+S GL Sbjct: 349 TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390 Score = 112 bits (281), Expect = 2e-24 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%) Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085 TPGPPGP+ GPPG+PG Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417 Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136 G+PG G PGP GPPG KG GDHGLPG G P GIP G+ GPKG Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471 Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GL G GLPG PG G +G+ G +G +G +G PG+ G TGLPG G G + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247 G+P + + V P P L + +PG + L G PGT +P Sbjct: 532 GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580 Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276 G +G L G +G+ G G GSPG G Sbjct: 581 GP--KGELALSGEKGDQGPPGDPGSPGSPG 608 Score = 107 bits (268), Expect = 6e-23 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102 PG PGP GPPG PG G PG +G GP GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142 +KGEKGD G G G PG G+PG GLQG G G+ G Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307 Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187 G G G RGF G+ G G G++ GPPG GPT G PGP G RG Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247 +G PQ + P +P PG G+PG Sbjct: 368 RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403 Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276 GE GR G+ G G PG G G PG G Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Score = 102 bits (255), Expect = 2e-21 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%) Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102 G T P V CS G G QG PGLPG G PG G G +G P Sbjct: 112 GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167 Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156 KG+ G G PG QG PG G PG VG GP G G G G GP G G +G Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227 Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 G +G +G GPPGTV GP T L G KG++G GEP Sbjct: 228 ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274 Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267 + P +K PG L G PG PG G G RG PG +G Sbjct: 275 ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324 Query: 1268 QMGSPGQQG 1276 + G GQ+G Sbjct: 325 EDGIKGQKG 333 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 142 bits (358), Expect = 2e-33 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122 GPPGP G PG PG+ G+PG G G RG PG KGE+GD G PG +G PG + Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG G +G GM GL+G GLP GPPGPRG G G G G RG PG++G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 G+PG KG+RG G P L ++ L + E TRP P Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067 Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 P G PG GE G+ G HL G GA G GSPG G Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113 Score = 138 bits (347), Expect = 4e-32 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 PGPPGP G PGLPG G GE G P GP GP G G G GLPG G G G Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177 G GL GP G+RG G G PG PGP RG QG G G +GE+G G + GP G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236 PG +G +G++G P + + + + E P P L + PG T G Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242 Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282 PG+R PG G G H+ G +G PG G MG PG+ GA T GL Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302 Score = 135 bits (340), Expect = 3e-31 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%) Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126 PGPPG G PG G G PG +G PG GPPG G G G G GHPG +G PG Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G GT GLPGP G GFQG G +G G G G++GP G GPKG G Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 +G+P +L + S + + PP P L P P G PG K Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G G + +GEPG G G PG +G Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430 Score = 127 bits (320), Expect = 5e-29 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%) Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107 S S+ PGPPGP GPPG PG G P G+ G PGP G PG+ G K Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708 Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159 GD G PG + G G G+PG+ GL G KG + G G PG PG RG G G Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203 G G G PGT G GL GP+G+ G+ G P Q L L L Q Sbjct: 769 EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828 Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263 K + P +P L++ PG GSPG +PG G G L RG P Sbjct: 829 QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876 Query: 1264 GAVGQMGSPGQQG 1276 G G +G PG+ G Sbjct: 877 GNPGILGPPGEDG 889 Score = 123 bits (309), Expect = 1e-27 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%) Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109 PGP GP+G PGLPG +G+PG G PG GP PG G KG+ Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161 G PGL G G+ GIPG GL+G KG E G GLPG PGP+G G G Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191 Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221 G G GPPG G G GP+G +G GE +++ T PP Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239 Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 P PGT + G ++ + GE G G GEPG G G PG+ S +G Sbjct: 240 P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288 Score = 121 bits (304), Expect = 4e-27 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090 P G P S PG PGP +GPPGLPG G+PG Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123 G PGPRG PG +G KGD G PG G PG +G Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157 IPG+ G +GP G RG G G PGPPG G +G Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269 Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196 G+ G G +GPPGT G GLPGP+G+ +GEKG P L + Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256 + PP PI K PG G PGT +PG G G Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365 Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276 GEPG G+ G PG G Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382 Score = 120 bits (300), Expect = 1e-26 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106 GPPG +GPPGLPG G+PG G PGPRG PG +G Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164 KGD G PG G PG +G G G +GP G+ G G GLPG PG G +G G+RG+ Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 G GPPG G + + G KG++G G P + P Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285 Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG LG+PGT +PG G G +G PG G+ G+PG G+ Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329 Score = 119 bits (299), Expect = 1e-26 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117 TPG PGP+G PG G G GE+G P GP+GPPGV+G+ G + L G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358 Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171 PG G PG G+Q GP G G G G PG G G G AG +G G +G PG Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 G GLPG KG+RG+ G P + T + ++ S + S E T P Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466 Score = 119 bits (298), Expect = 2e-26 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%) Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 PA C C + G G +G G PG G+PG++GF GP G PG +G KG GLP Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 GL G G +GI G L G G GL GT G GP G G G +G++G G G PGT+ Sbjct: 85 GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G+PG G +G+KG P +K D P + PG Sbjct: 142 GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192 Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276 P+G PG PG G G R + +GE G G G PG G Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 119 bits (298), Expect = 2e-26 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118 PG PGPQGPPG+PG G G+ G PGP G PG+ G KGD G PG +G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174 G G+PG+ GL G KG + G G PG PG RG G G G G G PGT G Sbjct: 724 GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783 Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218 GL GP+G+ G+ G P Q L L L Q K + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840 Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260 P +P L++ PG PLG PG PGE G G G Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280 G PG GQ GSPG G Q Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 117 bits (293), Expect = 7e-26 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%) Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106 C+ S PG PGP GPPG + R G PG+ G PG G PG+ KGE Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 G GLPGL G G +GIPGR G G KG G G GLPG PG G QG G +G G Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 E RG PG G G+PG G +G G LA + Q Sbjct: 542 ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268 PP +PG+ GSPG A PG +G L+G +G PGA G Sbjct: 597 ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1269 MGSPGQQG 1276 G G +G Sbjct: 639 PGEAGPRG 646 Score = 117 bits (293), Expect = 7e-26 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%) Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102 C+ PGPPG G PGL PG G PG GFPG +G PG Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158 +KGEKG+ G G+ G PG +G PGR GL G+ G G GLPGP G G Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592 Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218 G +G G+ G PG+ GP G GP G G +GEP T Q V A Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649 Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274 P+ PG P G PG + +PG G+ G L G GEPG +G G PG Sbjct: 650 VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1275 QG 1276 +G Sbjct: 708 KG 709 Score = 116 bits (291), Expect = 1e-25 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%) Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114 S +PGP GP GPPG PG GT G G PGP G G +GE G G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662 Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 GHPG QG PG GL GP G G+ G G PGPPGP+G QG G T G Sbjct: 663 PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 G PG +G GLPG G G KGEP + Sbjct: 719 SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274 PGT G PG R + GE G G L+G RG+PG G G G Sbjct: 748 MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Query: 1275 QGASTQG 1281 G +G Sbjct: 806 PGRCIEG 812 Score = 116 bits (290), Expect = 2e-25 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%) Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125 G PG G PG PG G+PG G PGP GPPG KG GDHGLPG G PG IP Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463 Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 G + GPKG GL G GLPG PG G +G+ G +G +G +G PG+ G TG Sbjct: 464 G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236 LPG G G +G+P + + V +P L+ PGT + G Sbjct: 521 LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578 Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282 PG + + + GE G G + G PG G G PG GL Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 115 bits (288), Expect = 3e-25 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107 G P+ +S PG G G PG G G PG +G PGP GPPG +G+ Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166 G G P G PG +GIPG +G G G +G GT G PG G G G+ G +G GE Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056 Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 GPPG G GLPG G++GE G+P P Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274 P + E GSPG K G+ G +G + L G RG PG G GSPG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 1275 QG 1276 G Sbjct: 1151 MG 1152 Score = 113 bits (283), Expect = 1e-24 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%) Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099 PGPPG QGPPG LPG NG G+QG FPG G Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144 PG+ G +G+ G G +G+PG+ GI PG +G GP G G G G Sbjct: 857 SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189 PG PG +G +G GA+G G++G PG G G PG KG RG G Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 P L L L A P P L + + +G PG++ K G Sbjct: 977 MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 GR GR G PG G G G+ G S Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059 Score = 113 bits (282), Expect = 1e-24 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122 G PG G PG PG G G +GFPG G G+KG+KGD G PG +G G + Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356 Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175 G PG G +G +G +G G G+PG PG RG G G +G+ GERG PG +G Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G PG G G G P PP I+ +K PG Sbjct: 417 PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451 Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278 G PG +PG G G ++ G G PG G G PG+QGA+ Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Score = 112 bits (281), Expect = 2e-24 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%) Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116 PG PGPQG PPG PG G PG GF GPRGP G GE KG+ G+ GL Sbjct: 176 PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235 Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165 G PG G V L GP KG +G +G G PGPPGP G G + GA G G Sbjct: 236 GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 +G PG G G PG +G +G +G P + K D R P + Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 E G E G+PG PG G RG G G G PG G+S GL Sbjct: 349 TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390 Score = 112 bits (281), Expect = 2e-24 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%) Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085 TPGPPGP+ GPPG+PG Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417 Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136 G+PG G PGP GPPG KG GDHGLPG G P GIP G+ GPKG Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471 Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GL G GLPG PG G +G+ G +G +G +G PG+ G TGLPG G G + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247 G+P + + V P P L + +PG + L G PGT +P Sbjct: 532 GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580 Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276 G +G L G +G+ G G GSPG G Sbjct: 581 GP--KGELALSGEKGDQGPPGDPGSPGSPG 608 Score = 107 bits (268), Expect = 6e-23 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102 PG PGP GPPG PG G PG +G GP GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142 +KGEKGD G G G PG G+PG GLQG G G+ G Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307 Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187 G G G RGF G+ G G G++ GPPG GPT G PGP G RG Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247 +G PQ + P +P PG G+PG Sbjct: 368 RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403 Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276 GE GR G+ G G PG G G PG G Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Score = 102 bits (255), Expect = 2e-21 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%) Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102 G T P V CS G G QG PGLPG G PG G G +G P Sbjct: 112 GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167 Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156 KG+ G G PG QG PG G PG VG GP G G G G GP G G +G Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227 Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 G +G +G GPPGTV GP T L G KG++G GEP Sbjct: 228 ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274 Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267 + P +K PG L G PG PG G G RG PG +G Sbjct: 275 ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324 Query: 1268 QMGSPGQQG 1276 + G GQ+G Sbjct: 325 EDGIKGQKG 333 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 142 bits (358), Expect = 2e-33 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122 GPPGP G PG PG+ G+PG G G RG PG KGE+GD G PG +G PG + Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG G +G GM GL+G GLP GPPGPRG G G G G RG PG++G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 G+PG KG+RG G P L ++ L + E TRP P Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067 Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 P G PG GE G+ G HL G GA G GSPG G Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113 Score = 138 bits (347), Expect = 4e-32 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 PGPPGP G PGLPG G GE G P GP GP G G G GLPG G G G Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177 G GL GP G+RG G G PG PGP RG QG G G +GE+G G + GP G Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236 PG +G +G++G P + + + + E P P L + PG T G Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242 Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282 PG+R PG G G H+ G +G PG G MG PG+ GA T GL Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302 Score = 135 bits (340), Expect = 3e-31 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%) Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126 PGPPG G PG G G PG +G PG GPPG G G G G GHPG +G PG Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G GT GLPGP G GFQG G +G G G G++GP G GPKG G Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 +G+P +L + S + + PP P L P P G PG K Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G G + +GEPG G G PG +G Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430 Score = 127 bits (320), Expect = 5e-29 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%) Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107 S S+ PGPPGP GPPG PG G P G+ G PGP G PG+ G K Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708 Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159 GD G PG + G G G+PG+ GL G KG + G G PG PG RG G G Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203 G G G PGT G GL GP+G+ G+ G P Q L L L Q Sbjct: 769 EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828 Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263 K + P +P L++ PG GSPG +PG G G L RG P Sbjct: 829 QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876 Query: 1264 GAVGQMGSPGQQG 1276 G G +G PG+ G Sbjct: 877 GNPGILGPPGEDG 889 Score = 123 bits (309), Expect = 1e-27 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%) Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109 PGP GP+G PGLPG +G+PG G PG GP PG G KG+ Sbjct: 72 PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131 Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161 G PGL G G+ GIPG GL+G KG E G GLPG PGP+G G G Sbjct: 132 QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191 Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221 G G GPPG G G GP+G +G GE +++ T PP Sbjct: 192 GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239 Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 P PGT + G ++ + GE G G GEPG G G PG+ S +G Sbjct: 240 P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288 Score = 121 bits (304), Expect = 4e-27 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090 P G P S PG PGP +GPPGLPG G+PG Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123 G PGPRG PG +G KGD G PG G PG +G Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157 IPG+ G +GP G RG G G PGPPG G +G Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269 Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196 G+ G G +GPPGT G GLPGP+G+ +GEKG P L + Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329 Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256 + PP PI K PG G PGT +PG G G Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365 Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276 GEPG G+ G PG G Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382 Score = 120 bits (300), Expect = 1e-26 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106 GPPG +GPPGLPG G+PG G PGPRG PG +G Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190 Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164 KGD G PG G PG +G G G +GP G+ G G GLPG PG G +G G+RG+ Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224 G GPPG G + + G KG++G G P + P Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285 Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG LG+PGT +PG G G +G PG G+ G+PG G+ Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329 Score = 119 bits (299), Expect = 1e-26 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117 TPG PGP+G PG G G GE+G P GP+GPPGV+G+ G + L G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358 Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171 PG G PG G+Q GP G G G G PG G G G AG +G G +G PG Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 G GLPG KG+RG+ G P + T + ++ S + S E T P Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466 Score = 119 bits (298), Expect = 2e-26 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%) Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 PA C C + G G +G G PG G+PG++GF GP G PG +G KG GLP Sbjct: 25 PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173 GL G G +GI G L G G GL GT G GP G G G +G++G G G PGT+ Sbjct: 85 GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 G G+PG G +G+KG P +K D P + PG Sbjct: 142 GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192 Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276 P+G PG PG G G R + +GE G G G PG G Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Score = 119 bits (298), Expect = 2e-26 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118 PG PGPQGPPG+PG G G+ G PGP G PG+ G KGD G PG +G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174 G G+PG+ GL G KG + G G PG PG RG G G G G G PGT G Sbjct: 724 GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783 Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218 GL GP+G+ G+ G P Q L L L Q K + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840 Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260 P +P L++ PG PLG PG PGE G G G Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280 G PG GQ GSPG G Q Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQ 926 Score = 117 bits (293), Expect = 7e-26 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%) Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106 C+ S PG PGP GPPG + R G PG+ G PG G PG+ KGE Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 G GLPGL G G +GIPGR G G KG G G GLPG PG G QG G +G G Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 E RG PG G G+PG G +G G LA + Q Sbjct: 542 ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268 PP +PG+ GSPG A PG +G L+G +G PGA G Sbjct: 597 ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1269 MGSPGQQG 1276 G G +G Sbjct: 639 PGEAGPRG 646 Score = 117 bits (293), Expect = 7e-26 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%) Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102 C+ PGPPG G PGL PG G PG GFPG +G PG Sbjct: 476 CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535 Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158 +KGEKG+ G G+ G PG +G PGR GL G+ G G GLPGP G G Sbjct: 536 LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592 Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218 G +G G+ G PG+ GP G GP G G +GEP T Q V A Sbjct: 593 GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649 Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274 P+ PG P G PG + +PG G+ G L G GEPG +G G PG Sbjct: 650 VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 1275 QG 1276 +G Sbjct: 708 KG 709 Score = 116 bits (291), Expect = 1e-25 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%) Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114 S +PGP GP GPPG PG GT G G PGP G G +GE G G PG Sbjct: 603 SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662 Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 GHPG QG PG GL GP G G+ G G PGPPGP+G QG G T G Sbjct: 663 PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 G PG +G GLPG G G KGEP + Sbjct: 719 SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274 PGT G PG R + GE G G L+G RG+PG G G G Sbjct: 748 MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805 Query: 1275 QGASTQG 1281 G +G Sbjct: 806 PGRCIEG 812 Score = 116 bits (290), Expect = 2e-25 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%) Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125 G PG G PG PG G+PG G PGP GPPG KG GDHGLPG G PG IP Sbjct: 407 GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463 Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 G + GPKG GL G GLPG PG G +G+ G +G +G +G PG+ G TG Sbjct: 464 G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236 LPG G G +G+P + + V +P L+ PGT + G Sbjct: 521 LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578 Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282 PG + + + GE G G + G PG G G PG GL Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Score = 115 bits (288), Expect = 3e-25 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107 G P+ +S PG G G PG G G PG +G PGP GPPG +G+ Sbjct: 940 GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999 Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166 G G P G PG +GIPG +G G G +G GT G PG G G G+ G +G GE Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056 Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219 GPPG G GLPG G++GE G+P P Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090 Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274 P + E GSPG K G+ G +G + L G RG PG G GSPG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 1275 QG 1276 G Sbjct: 1151 MG 1152 Score = 113 bits (283), Expect = 1e-24 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%) Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099 PGPPG QGPPG LPG NG G+QG FPG G Sbjct: 797 PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856 Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144 PG+ G +G+ G G +G+PG+ GI PG +G GP G G G G Sbjct: 857 SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189 PG PG +G +G GA+G G++G PG G G PG KG RG G Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976 Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249 P L L L A P P L + + +G PG++ K G Sbjct: 977 MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034 Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 GR GR G PG G G G+ G S Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059 Score = 113 bits (282), Expect = 1e-24 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122 G PG G PG PG G G +GFPG G G+KG+KGD G PG +G G + Sbjct: 297 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356 Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175 G PG G +G +G +G G G+PG PG RG G G +G+ GERG PG +G Sbjct: 357 GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G PG G G G P PP I+ +K PG Sbjct: 417 PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451 Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278 G PG +PG G G ++ G G PG G G PG+QGA+ Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Score = 112 bits (281), Expect = 2e-24 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%) Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116 PG PGPQG PPG PG G PG GF GPRGP G GE KG+ G+ GL Sbjct: 176 PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235 Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165 G PG G V L GP KG +G +G G PGPPGP G G + GA G G Sbjct: 236 GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 +G PG G G PG +G +G +G P + K D R P + Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 E G E G+PG PG G RG G G G PG G+S GL Sbjct: 349 TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390 Score = 112 bits (281), Expect = 2e-24 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%) Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085 TPGPPGP+ GPPG+PG Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417 Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136 G+PG G PGP GPPG KG GDHGLPG G P GIP G+ GPKG Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471 Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GL G GLPG PG G +G+ G +G +G +G PG+ G TGLPG G G + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247 G+P + + V P P L + +PG + L G PGT +P Sbjct: 532 GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580 Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276 G +G L G +G+ G G GSPG G Sbjct: 581 GP--KGELALSGEKGDQGPPGDPGSPGSPG 608 Score = 107 bits (268), Expect = 6e-23 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%) Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102 PG PGP GPPG PG G PG +G GP GPPG Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142 +KGEKGD G G G PG G+PG GLQG G G+ G Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307 Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187 G G G RGF G+ G G G++ GPPG GPT G PGP G RG Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247 +G PQ + P +P PG G+PG Sbjct: 368 RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403 Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276 GE GR G+ G G PG G G PG G Sbjct: 404 GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433 Score = 102 bits (255), Expect = 2e-21 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%) Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102 G T P V CS G G QG PGLPG G PG G G +G P Sbjct: 112 GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167 Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156 KG+ G G PG QG PG G PG VG GP G G G G GP G G +G Sbjct: 168 DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227 Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208 G +G +G GPPGTV GP T L G KG++G GEP Sbjct: 228 ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274 Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267 + P +K PG L G PG PG G G RG PG +G Sbjct: 275 ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324 Query: 1268 QMGSPGQQG 1276 + G GQ+G Sbjct: 325 EDGIKGQKG 333 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 141 bits (356), Expect = 4e-33 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120 PGPPGP G GLPG G G +G PGP+G P G++G G+ GLPG QG PG Sbjct: 999 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058 Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173 QG PG VG G +G G G GLPG PGP+G G AG +G GE+GP G Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1118 Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GP GLPGP G G GE + + + S K ++ PP P PG Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1166 Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 + P+G+PG PG G+ G + +G+ GA G G PG G QGL Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1214 Score = 133 bits (335), Expect = 1e-30 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127 T G GP GPPG G G G GFPGP+GPPG G+ G G PG +G G QG G Sbjct: 917 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976 Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183 VG QGP G G G G PGPPGP G QG+ GA G G +G PG G +G GP G Sbjct: 977 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036 Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243 RG GE + + A PP P+ GSPG R Sbjct: 1037 LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1076 Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 A G G GR +G PG G+ G+PG++G Sbjct: 1077 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1108 Score = 133 bits (335), Expect = 1e-30 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGPQGPPG G G PGE+G GP G GV+G G G G G PG G G +G Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145 Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169 G KG +G +G G PGPPG PRG QGM G +G G RG P Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1205 Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229 PG +G GLPGP GE+GE G+ + PP P Q Sbjct: 1206 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1245 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P G PG+ GE +GEPG G G PG+ G Sbjct: 1246 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1282 Score = 133 bits (334), Expect = 1e-30 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%) Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 GPPGP G P G PG +G GE G PGP+GP GV+G G G PG +G PG G Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600 Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173 G G G KG RG +G GLPG PPGP G GM G G G RG PG Sbjct: 601 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 GP GL GP+G G G+P + + P P Q+ PG Sbjct: 661 GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 709 Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 P G PG + PGE G G+ G PGA G G PG++G S Sbjct: 710 PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 753 Score = 131 bits (329), Expect = 5e-30 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%) Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 PGP G PQG PG PG+ G PG QG PGP+GP G GEKG G PGL G PG G PG Sbjct: 687 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746 Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 G +G G +G G G GP PGPRG +G G RG G +G G G G G G Sbjct: 747 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 806 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244 +G++GE + + + P +PG P G G + K Sbjct: 807 KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 849 Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 VPG G GR +G G+ G G PG G Sbjct: 850 GVPGLPGYPGR----QGPKGSTGFPGFPGANG 877 Score = 131 bits (329), Expect = 5e-30 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPGP G GLPG G GE G GP GPPG G +G G G G QG PG VG Sbjct: 1203 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1259 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G G +G G AG PGPPG G G G RG GE GPPG GP G GP G+ G KG Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242 P + F P P + + +PG G PG Sbjct: 1320 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1363 Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 +A PG G+ RG PGA G G G++GA Sbjct: 1364 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1391 Score = 131 bits (329), Expect = 5e-30 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPG +GPPG G G PG GFPG GPPG G G G+ G +G G G PG G Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G G G G G PG G G QG GA+G +G GPPG GP G GP G+ G P Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1418 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251 + L + P P+ EQ L G PG +PG G Sbjct: 1419 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1456 Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276 G E +G PG +G +G PG+QG Sbjct: 1457 DPGSKGE-KGHPGLIGLIGPPGEQG 1480 Score = 130 bits (327), Expect = 8e-30 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%) Query: 997 GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056 GE GS AG + L +GP + + A ++ + PA RDG Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1119 Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116 P + + + +PG G +G G PG+ G+ G++G GP GPPG++G G G+ G Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1179 Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG + G QG G +G EG G PGPPGP G QG+ G G GE G G +GP Sbjct: 1180 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233 Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229 G PGP+G +G G PQ PP + + +K E Sbjct: 1234 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1268 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G+PG +A V G G G E G PGA G G+ G G Sbjct: 1269 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1312 Score = 122 bits (305), Expect = 3e-27 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P GE G P G RGP ++ A Q + A + E P + G Sbjct: 1361 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1405 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 P + G PGP G GLP G G+ G PGP GPPG+ G KGD G G Sbjct: 1406 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1462 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159 +GHPG G+ G G QG KG RGL GT G P GPPGP G G G Sbjct: 1463 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1522 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 +G G GP G G +GLPGP G G GE Sbjct: 1523 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553 Score = 120 bits (302), Expect = 6e-27 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128 G PGP G G G+ G PG G+PG +GP KG G G PG G G +G+ PG Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 891 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G +GP G RG G G G PGP+G G G G GERGP G GP G PGPKG G Sbjct: 892 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 951 Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243 G+ H + F T PP P + Q T P+G G Sbjct: 952 GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 PGE G G EG +G+PG G G G G Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036 Score = 120 bits (300), Expect = 1e-26 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%) Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115 S S PGP GP QGPPG PG+ G PG G G G PG KG++G GLPGL Sbjct: 561 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 620 Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151 G GH+G PG G++G P+G+ G GT G PG PG Sbjct: 621 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680 Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199 G G G +G GE GPP G GP GLPGP+ GE+G +G+P LA L Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 739 Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256 H K E PP P P+G PG R G G +G + Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 790 Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276 +G G PG G MG G +G Sbjct: 791 EKGEDGFPGFKGDMGLKGDRG 811 Score = 120 bits (300), Expect = 1e-26 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G GP G G G G G G GP G GEKG G+PGL G+PG QG G G Sbjct: 811 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185 G G G +G G+ G PGPRG +G G RG+ G RGP G GP G PGP GER Sbjct: 871 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G PQ F PP P + L G G + K Sbjct: 931 GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282 PG G G GE G +G+ G PG G QGL Sbjct: 974 PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 1010 Score = 117 bits (293), Expect = 7e-26 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%) Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 PG PG QGP PG PG NG G +G PGPRG G G +G G G G PG Sbjct: 855 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914 Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 +G PG G QGP+G G G G PGPPG G G G RG +G +G G Sbjct: 915 KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 974 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228 GP G+ GP+G GE G + + H PP P EQ L Sbjct: 975 PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 1014 Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275 +PG + + G G PGE G G G G G G +GSPG++ Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074 Query: 1276 GAS 1278 G++ Sbjct: 1075 GSA 1077 Score = 117 bits (292), Expect = 9e-26 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%) Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114 GPPGP GP G+ PG G G G PG RGPPG G G GLPG Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 L+G PG G+ GR G G G G +G +G PGP Sbjct: 514 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 GPRG QG G G G+RG PG G G+PG G +G++G L L H + Sbjct: 574 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 629 Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254 PP P I + L P G G R PG+ G G Sbjct: 630 ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 685 Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276 ++ +GEPG GQ G+PG QG Sbjct: 686 PPGPKGNMGPQGEPGPPGQQGNPGPQG 712 Score = 116 bits (290), Expect = 2e-25 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%) Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125 G PG QG PGL G G PG G PG RG G G G G PG QG P G +G P Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170 G G QGP G G++G GLPGP GP G +G G +G +G GPP Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1164 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226 G GP G PG G GE G P+ Q K D E R PP PI Q Sbjct: 1165 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1212 Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275 L PG + P+G PG PG G +G +G +G PG+VG +G G++ Sbjct: 1213 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266 Query: 1276 G 1276 G Sbjct: 1267 G 1267 Score = 104 bits (259), Expect = 6e-22 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103 PGPPG +GPPG G G GE+G PGP RG PG Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427 Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163 GE+G G G G PG G PG GL+G G +G +G GL G GP G QG G RG Sbjct: 1428 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1487 Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G +G PG G G+PGP G G G P Sbjct: 1488 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515 Score = 67.0 bits (162), Expect = 1e-10 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%) Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132 PP + PG+P E G G GEKG G P + PG + ++G Sbjct: 408 PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 454 Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192 P PGP GP G G G +G +G G PG GP G PG G G G P Sbjct: 455 P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 502 Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240 ++ L SK + IL+Q + PG P+G PG+ Sbjct: 503 TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 560 Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277 G+ G +G R ++G RG PGA G G PG+ GA Sbjct: 561 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608 Score = 52.4 bits (124), Expect = 3e-06 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 PGP GP GPPG PG G GP+G G G G G GL G PG G PG V Sbjct: 1503 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554 Score = 35.8 bits (81), Expect = 0.27 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928 G + + K AQL+ ++P P + +I+F V+ P++ + ++ + Sbjct: 69 GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123 Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988 + + ++ G+ + F D + I G +H+V ++V + V + VDC Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182 Query: 989 RKVAERPL 996 +K +PL Sbjct: 183 KKKTTKPL 190 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 141 bits (356), Expect = 4e-33 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120 PGPPGP G GLPG G G +G PGP+G P G++G G+ GLPG QG PG Sbjct: 948 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007 Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173 QG PG VG G +G G G GLPG PGP+G G AG +G GE+GP G Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1067 Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GP GLPGP G G GE + + + S K ++ PP P PG Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1115 Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 + P+G+PG PG G+ G + +G+ GA G G PG G QGL Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1163 Score = 133 bits (335), Expect = 1e-30 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127 T G GP GPPG G G G GFPGP+GPPG G+ G G PG +G G QG G Sbjct: 866 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925 Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183 VG QGP G G G G PGPPGP G QG+ GA G G +G PG G +G GP G Sbjct: 926 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985 Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243 RG GE + + A PP P+ GSPG R Sbjct: 986 LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1025 Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 A G G GR +G PG G+ G+PG++G Sbjct: 1026 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1057 Score = 133 bits (335), Expect = 1e-30 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGPQGPPG G G PGE+G GP G GV+G G G G G PG G G +G Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094 Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169 G KG +G +G G PGPPG PRG QGM G +G G RG P Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154 Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229 PG +G GLPGP GE+GE G+ + PP P Q Sbjct: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1194 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P G PG+ GE +GEPG G G PG+ G Sbjct: 1195 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1231 Score = 133 bits (334), Expect = 1e-30 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%) Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 GPPGP G P G PG +G GE G PGP+GP GV+G G G PG +G PG G Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549 Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173 G G G KG RG +G GLPG PPGP G GM G G G RG PG Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 GP GL GP+G G G+P + + P P Q+ PG Sbjct: 610 GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 658 Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 P G PG + PGE G G+ G PGA G G PG++G S Sbjct: 659 PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 702 Score = 131 bits (329), Expect = 5e-30 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%) Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 PGP G PQG PG PG+ G PG QG PGP+GP G GEKG G PGL G PG G PG Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695 Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 G +G G +G G G GP PGPRG +G G RG G +G G G G G G Sbjct: 696 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244 +G++GE + + + P +PG P G G + K Sbjct: 756 KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 798 Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 VPG G GR +G G+ G G PG G Sbjct: 799 GVPGLPGYPGR----QGPKGSTGFPGFPGANG 826 Score = 131 bits (329), Expect = 5e-30 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPGP G GLPG G GE G GP GPPG G +G G G G QG PG VG Sbjct: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1208 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G G +G G AG PGPPG G G G RG GE GPPG GP G GP G+ G KG Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242 P + F P P + + +PG G PG Sbjct: 1269 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1312 Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 +A PG G+ RG PGA G G G++GA Sbjct: 1313 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1340 Score = 131 bits (329), Expect = 5e-30 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPG +GPPG G G PG GFPG GPPG G G G+ G +G G G PG G Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G G G G G PG G G QG GA+G +G GPPG GP G GP G+ G P Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1367 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251 + L + P P+ EQ L G PG +PG G Sbjct: 1368 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1405 Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276 G E +G PG +G +G PG+QG Sbjct: 1406 DPGSKGE-KGHPGLIGLIGPPGEQG 1429 Score = 130 bits (327), Expect = 8e-30 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%) Query: 997 GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056 GE GS AG + L +GP + + A ++ + PA RDG Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1068 Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116 P + + + +PG G +G G PG+ G+ G++G GP GPPG++G G G+ G Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1128 Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG + G QG G +G EG G PGPPGP G QG+ G G GE G G +GP Sbjct: 1129 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182 Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229 G PGP+G +G G PQ PP + + +K E Sbjct: 1183 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1217 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G+PG +A V G G G E G PGA G G+ G G Sbjct: 1218 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1261 Score = 122 bits (305), Expect = 3e-27 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P GE G P G RGP ++ A Q + A + E P + G Sbjct: 1310 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1354 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 P + G PGP G GLP G G+ G PGP GPPG+ G KGD G G Sbjct: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1411 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159 +GHPG G+ G G QG KG RGL GT G P GPPGP G G G Sbjct: 1412 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1471 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 +G G GP G G +GLPGP G G GE Sbjct: 1472 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502 Score = 120 bits (302), Expect = 6e-27 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128 G PGP G G G+ G PG G+PG +GP KG G G PG G G +G+ PG Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 840 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G +GP G RG G G G PGP+G G G G GERGP G GP G PGPKG G Sbjct: 841 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 900 Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243 G+ H + F T PP P + Q T P+G G Sbjct: 901 GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 PGE G G EG +G+PG G G G G Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985 Score = 120 bits (300), Expect = 1e-26 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%) Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115 S S PGP GP QGPPG PG+ G PG G G G PG KG++G GLPGL Sbjct: 510 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 569 Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151 G GH+G PG G++G P+G+ G GT G PG PG Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629 Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199 G G G +G GE GPP G GP GLPGP+ GE+G +G+P LA L Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 688 Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256 H K E PP P P+G PG R G G +G + Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 739 Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276 +G G PG G MG G +G Sbjct: 740 EKGEDGFPGFKGDMGLKGDRG 760 Score = 120 bits (300), Expect = 1e-26 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G GP G G G G G G GP G GEKG G+PGL G+PG QG G G Sbjct: 760 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185 G G G +G G+ G PGPRG +G G RG+ G RGP G GP G PGP GER Sbjct: 820 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G PQ F PP P + L G G + K Sbjct: 880 GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282 PG G G GE G +G+ G PG G QGL Sbjct: 923 PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 959 Score = 117 bits (293), Expect = 7e-26 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%) Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 PG PG QGP PG PG NG G +G PGPRG G G +G G G G PG Sbjct: 804 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863 Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 +G PG G QGP+G G G G PGPPG G G G RG +G +G G Sbjct: 864 KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228 GP G+ GP+G GE G + + H PP P EQ L Sbjct: 924 PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 963 Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275 +PG + + G G PGE G G G G G G +GSPG++ Sbjct: 964 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023 Query: 1276 GAS 1278 G++ Sbjct: 1024 GSA 1026 Score = 117 bits (292), Expect = 9e-26 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%) Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114 GPPGP GP G+ PG G G G PG RGPPG G G GLPG Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 L+G PG G+ GR G G G G +G +G PGP Sbjct: 463 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 GPRG QG G G G+RG PG G G+PG G +G++G L L H + Sbjct: 523 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 578 Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254 PP P I + L P G G R PG+ G G Sbjct: 579 ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 634 Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276 ++ +GEPG GQ G+PG QG Sbjct: 635 PPGPKGNMGPQGEPGPPGQQGNPGPQG 661 Score = 116 bits (290), Expect = 2e-25 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%) Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125 G PG QG PGL G G PG G PG RG G G G G PG QG P G +G P Sbjct: 994 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170 G G QGP G G++G GLPGP GP G +G G +G +G GPP Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226 G GP G PG G GE G P+ Q K D E R PP PI Q Sbjct: 1114 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1161 Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275 L PG + P+G PG PG G +G +G +G PG+VG +G G++ Sbjct: 1162 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215 Query: 1276 G 1276 G Sbjct: 1216 G 1216 Score = 104 bits (259), Expect = 6e-22 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103 PGPPG +GPPG G G GE+G PGP RG PG Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376 Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163 GE+G G G G PG G PG GL+G G +G +G GL G GP G QG G RG Sbjct: 1377 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1436 Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G +G PG G G+PGP G G G P Sbjct: 1437 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464 Score = 67.0 bits (162), Expect = 1e-10 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%) Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132 PP + PG+P E G G GEKG G P + PG + ++G Sbjct: 357 PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 403 Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192 P PGP GP G G G +G +G G PG GP G PG G G G P Sbjct: 404 P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 451 Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240 ++ L SK + IL+Q + PG P+G PG+ Sbjct: 452 TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 509 Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277 G+ G +G R ++G RG PGA G G PG+ GA Sbjct: 510 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557 Score = 52.4 bits (124), Expect = 3e-06 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 PGP GP GPPG PG G GP+G G G G G GL G PG G PG V Sbjct: 1452 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503 Score = 35.8 bits (81), Expect = 0.27 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928 G + + K AQL+ ++P P + +I+F V+ P++ + ++ + Sbjct: 69 GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123 Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988 + + ++ G+ + F D + I G +H+V ++V + V + VDC Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182 Query: 989 RKVAERPL 996 +K +PL Sbjct: 183 KKKTTKPL 190 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 141 bits (356), Expect = 4e-33 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120 PGPPGP G GLPG G G +G PGP+G P G++G G+ GLPG QG PG Sbjct: 987 PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046 Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173 QG PG VG G +G G G GLPG PGP+G G AG +G GE+GP G Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1106 Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232 GP GLPGP G G GE + + + S K ++ PP P PG Sbjct: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1154 Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282 + P+G+PG PG G+ G + +G+ GA G G PG G QGL Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1202 Score = 133 bits (335), Expect = 1e-30 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127 T G GP GPPG G G G GFPGP+GPPG G+ G G PG +G G QG G Sbjct: 905 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964 Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183 VG QGP G G G G PGPPGP G QG+ GA G G +G PG G +G GP G Sbjct: 965 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024 Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243 RG GE + + A PP P+ GSPG R Sbjct: 1025 LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1064 Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 A G G GR +G PG G+ G+PG++G Sbjct: 1065 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1096 Score = 133 bits (335), Expect = 1e-30 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGPQGPPG G G PGE+G GP G GV+G G G G G PG G G +G Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133 Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169 G KG +G +G G PGPPG PRG QGM G +G G RG P Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193 Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229 PG +G GLPGP GE+GE G+ + PP P Q Sbjct: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1233 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P G PG+ GE +GEPG G G PG+ G Sbjct: 1234 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1270 Score = 133 bits (334), Expect = 1e-30 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%) Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 GPPGP G P G PG +G GE G PGP+GP GV+G G G PG +G PG G Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588 Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173 G G G KG RG +G GLPG PPGP G GM G G G RG PG Sbjct: 589 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648 Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233 GP GL GP+G G G+P + + P P Q+ PG Sbjct: 649 GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 697 Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 P G PG + PGE G G+ G PGA G G PG++G S Sbjct: 698 PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 741 Score = 131 bits (329), Expect = 5e-30 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%) Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 PGP G PQG PG PG+ G PG QG PGP+GP G GEKG G PGL G PG G PG Sbjct: 675 PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734 Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 G +G G +G G G GP PGPRG +G G RG G +G G G G G G Sbjct: 735 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244 +G++GE + + + P +PG P G G + K Sbjct: 795 KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 837 Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 VPG G GR +G G+ G G PG G Sbjct: 838 GVPGLPGYPGR----QGPKGSTGFPGFPGANG 865 Score = 131 bits (329), Expect = 5e-30 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PGPPGP G GLPG G GE G GP GPPG G +G G G G QG PG VG Sbjct: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1247 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G G +G G AG PGPPG G G G RG GE GPPG GP G GP G+ G KG Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242 P + F P P + + +PG G PG Sbjct: 1308 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1351 Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 +A PG G+ RG PGA G G G++GA Sbjct: 1352 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1379 Score = 131 bits (329), Expect = 5e-30 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPG +GPPG G G PG GFPG GPPG G G G+ G +G G G PG G Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G G G G G PG G G QG GA+G +G GPPG GP G GP G+ G P Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1406 Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251 + L + P P+ EQ L G PG +PG G Sbjct: 1407 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1444 Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276 G E +G PG +G +G PG+QG Sbjct: 1445 DPGSKGE-KGHPGLIGLIGPPGEQG 1468 Score = 130 bits (327), Expect = 8e-30 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%) Query: 997 GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056 GE GS AG + L +GP + + A ++ + PA RDG Sbjct: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1107 Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116 P + + + +PG G +G G PG+ G+ G++G GP GPPG++G G G+ G Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1167 Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G PG + G QG G +G EG G PGPPGP G QG+ G G GE G G +GP Sbjct: 1168 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221 Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229 G PGP+G +G G PQ PP + + +K E Sbjct: 1222 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1256 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 PG G+PG +A V G G G E G PGA G G+ G G Sbjct: 1257 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1300 Score = 122 bits (305), Expect = 3e-27 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P GE G P G RGP ++ A Q + A + E P + G Sbjct: 1349 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1393 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114 P + G PGP G GLP G G+ G PGP GPPG+ G KGD G G Sbjct: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1450 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159 +GHPG G+ G G QG KG RGL GT G P GPPGP G G G Sbjct: 1451 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1510 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 +G G GP G G +GLPGP G G GE Sbjct: 1511 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541 Score = 120 bits (302), Expect = 6e-27 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128 G PGP G G G+ G PG G+PG +GP KG G G PG G G +G+ PG Sbjct: 823 GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 879 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G +GP G RG G G G PGP+G G G G GERGP G GP G PGPKG G Sbjct: 880 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 939 Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243 G+ H + F T PP P + Q T P+G G Sbjct: 940 GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 PGE G G EG +G+PG G G G G Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024 Score = 120 bits (300), Expect = 1e-26 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%) Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115 S S PGP GP QGPPG PG+ G PG G G G PG KG++G GLPGL Sbjct: 549 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 608 Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151 G GH+G PG G++G P+G+ G GT G PG PG Sbjct: 609 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668 Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199 G G G +G GE GPP G GP GLPGP+ GE+G +G+P LA L Sbjct: 669 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 727 Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256 H K E PP P P+G PG R G G +G + Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 778 Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276 +G G PG G MG G +G Sbjct: 779 EKGEDGFPGFKGDMGLKGDRG 799 Score = 120 bits (300), Expect = 1e-26 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G GP G G G G G G GP G GEKG G+PGL G+PG QG G G Sbjct: 799 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185 G G G +G G+ G PGPRG +G G RG+ G RGP G GP G PGP GER Sbjct: 859 GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G PQ F PP P + L G G + K Sbjct: 919 GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282 PG G G GE G +G+ G PG G QGL Sbjct: 962 PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 998 Score = 117 bits (293), Expect = 7e-26 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%) Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121 PG PG QGP PG PG NG G +G PGPRG G G +G G G G PG Sbjct: 843 PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902 Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172 +G PG G QGP+G G G G PGPPG G G G RG +G +G G Sbjct: 903 KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962 Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228 GP G+ GP+G GE G + + H PP P EQ L Sbjct: 963 PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 1002 Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275 +PG + + G G PGE G G G G G G +GSPG++ Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062 Query: 1276 GAS 1278 G++ Sbjct: 1063 GSA 1065 Score = 117 bits (292), Expect = 9e-26 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%) Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114 GPPGP GP G+ PG G G G PG RGPPG G G GLPG Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 L+G PG G+ GR G G G G +G +G PGP Sbjct: 502 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 GPRG QG G G G+RG PG G G+PG G +G++G L L H + Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 617 Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254 PP P I + L P G G R PG+ G G Sbjct: 618 ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 673 Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276 ++ +GEPG GQ G+PG QG Sbjct: 674 PPGPKGNMGPQGEPGPPGQQGNPGPQG 700 Score = 116 bits (290), Expect = 2e-25 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%) Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125 G PG QG PGL G G PG G PG RG G G G G PG QG P G +G P Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170 G G QGP G G++G GLPGP GP G +G G +G +G GPP Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226 G GP G PG G GE G P+ Q K D E R PP PI Q Sbjct: 1153 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1200 Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275 L PG + P+G PG PG G +G +G +G PG+VG +G G++ Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254 Query: 1276 G 1276 G Sbjct: 1255 G 1255 Score = 104 bits (259), Expect = 6e-22 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103 PGPPG +GPPG G G GE+G PGP RG PG Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415 Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163 GE+G G G G PG G PG GL+G G +G +G GL G GP G QG G RG Sbjct: 1416 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1475 Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G +G PG G G+PGP G G G P Sbjct: 1476 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503 Score = 67.0 bits (162), Expect = 1e-10 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%) Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132 PP + PG+P E G G GEKG G P + PG + ++G Sbjct: 396 PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 442 Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192 P PGP GP G G G +G +G G PG GP G PG G G G P Sbjct: 443 P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 490 Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240 ++ L SK + IL+Q + PG P+G PG+ Sbjct: 491 TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 548 Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277 G+ G +G R ++G RG PGA G G PG+ GA Sbjct: 549 SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596 Score = 52.4 bits (124), Expect = 3e-06 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 PGP GP GPPG PG G GP+G G G G G GL G PG G PG V Sbjct: 1491 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542 Score = 35.8 bits (81), Expect = 0.27 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928 G + + K AQL+ ++P P + +I+F V+ P++ + ++ + Sbjct: 69 GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123 Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988 + + ++ G+ + F D + I G +H+V ++V + V + VDC Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182 Query: 989 RKVAERPL 996 +K +PL Sbjct: 183 KKKTTKPL 190 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 141 bits (356), Expect = 4e-33 Identities = 93/228 (40%), Positives = 112/228 (49%), Gaps = 21/228 (9%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PG GP G G G PGE+G PG G PG KG G HG G +G PG G PG G Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G +GM G G AG PGP G RG G GA GT+G G G GP G PGP G GEKGE Sbjct: 758 PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817 Query: 1191 PQSLATLYQLVSQASHVSKFDSFHEN----TRPPMP-----ILEQKLEPGTE-PLGSPGT 1240 P + S+ + S+ ++ P P + + EPG + GSPG Sbjct: 818 PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877 Query: 1241 RSKALVPGEWG-------RGGRHLEG----RGEPGAVGQMGSPGQQGA 1277 + A PG G +GGR +G G PG+ G++G PG GA Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGA 925 Score = 135 bits (341), Expect = 2e-31 Identities = 87/214 (40%), Positives = 106/214 (49%), Gaps = 18/214 (8%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 GPPG +G PG G NG G GF GP+GP PGVKGE G+ G G G PG QG+ G Sbjct: 825 GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP 884 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G GP G+ GL+G G GPPG GF G AG G G G PG GP G PG +G G + Sbjct: 885 GPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----PLGSPGTRSKA 1244 G+P S + V + P + +PG + P G+ G R Sbjct: 945 GDPGS----HGRVGDRGPAGPPGGPGDKGDP-----GEDGQPGPDGPPGPAGTTGQRGIV 995 Query: 1245 LVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 +PG+ G RG L G G PG VG G+ G +G Sbjct: 996 GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKG 1029 Score = 133 bits (335), Expect = 1e-30 Identities = 89/216 (41%), Positives = 103/216 (47%), Gaps = 27/216 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP G PG G G G++G PGP GPPG G G+ PG +G G+ G PGR G Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE---PGPEGPAGNDGTPGRDGA 1063 Query: 1131 QGPKGMRGLEGTAGLPGP------PGPRGFQGMAGARGTSGERGP---PGTVGPTGLPGP 1181 G +G RG G AGLPG PGP G G AG RG G RGP PG G GLPGP Sbjct: 1064 VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGP 1123 Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241 +G RG+KG+ Q H F PP P EQ G PG Sbjct: 1124 QGPRGDKGDHGDRGDR----GQKGH-RGFTGLQGLPGPPGPNGEQ------GSAGIPGPF 1172 Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 PG G G+ G PG +G +G PG +G+ Sbjct: 1173 GPRGPPGPVGPSGK----EGNPGPLGPIGPPGVRGS 1204 Score = 132 bits (332), Expect = 2e-30 Identities = 83/208 (39%), Positives = 105/208 (50%), Gaps = 27/208 (12%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG +GPPGL G G+ G G GP GPPG G+KGD PG G PG G PG G Sbjct: 933 GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD---PGEDGQPGPDGPPGPAGTT 989 Query: 1132 GPKG---MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G +G M G G G+PG PGP G G G G +G++GPPG VGP G GP GE G + Sbjct: 990 GQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE 1049 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 G + T + + + D P P PG++ G+PGT PG Sbjct: 1050 GPAGNDGTPGRDGAVGERGDRGD--------PGP----AGLPGSQ--GAPGTPGPVGAPG 1095 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 + G+ RG+PG+ G +G PG+ G Sbjct: 1096 DAGQ-------RGDPGSRGPIGPPGRAG 1116 Score = 130 bits (328), Expect = 6e-30 Identities = 87/220 (39%), Positives = 99/220 (45%), Gaps = 28/220 (12%) Query: 1072 GPPGPQGPPGLPGRNG------TPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125 GP GP+GP GL G+ G PGE G PGP GP G +G +G G PG G PG G P Sbjct: 216 GPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP 275 Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185 G VG G G RG G GLPG G RG +G+ G +G G G G GPTG G G Sbjct: 276 GEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPL 335 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G P L + H P P+ PLG PG+ Sbjct: 336 GPRGMPGERGRLGPQGAPGQR-----GAHGMPGKPGPM---------GPLGIPGSSGFPG 381 Query: 1246 VPGEWGR----GGRHLEG----RGEPGAVGQMGSPGQQGA 1277 PG G G R EG RGE G G +GSPG GA Sbjct: 382 NPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421 Score = 130 bits (327), Expect = 8e-30 Identities = 110/326 (33%), Positives = 129/326 (39%), Gaps = 92/326 (28%) Query: 995 PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054 P+G +G P ++GF + GP + R E P + G Sbjct: 367 PMGPLGIPGSSGFPGNPGMKGEAGPTGA---------------------RGPEGPQGQRG 405 Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGT------------PGEQGFPGPRGPPG 1102 ET GPPGP G PGLPG GT PG G PG GPPG Sbjct: 406 ET---------------GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450 Query: 1103 VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP------GPRGFQG 1156 G +G G G++G PG G+PG G GPKG G G G GPP GPRG G Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510 Query: 1157 MAGARGTSGERGPPGT---VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 G G GERG PG G GLPGPKG +GE+G S S Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK-------------GSQ 557 Query: 1214 HENTRPPMPILEQKL----EPGTE-------PLGSPGTRSKALVPGEWG----RGGRHLE 1258 + RP P L PG + PLG+PG + PG G G L Sbjct: 558 GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLP 617 Query: 1259 G-------RGEPGAVGQMGSPGQQGA 1277 G G+PG G G PGQ+GA Sbjct: 618 GPKGSSGDPGKPGEAGNAGVPGQRGA 643 Score = 129 bits (324), Expect = 2e-29 Identities = 86/236 (36%), Positives = 104/236 (44%), Gaps = 22/236 (9%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P G+ P + S G GP GPPG PG G PGE G PGP GPPG G G Sbjct: 931 PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168 G+ G+ G G +G+PG G G G G G G GPPGP G G G G G G Sbjct: 991 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG 1050 Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPI----- 1223 P G G G G GERG++G+P + P P+ Sbjct: 1051 PAGNDGTPGRDGAVGERGDRGDPGP--------------AGLPGSQGAPGTPGPVGAPGD 1096 Query: 1224 LEQKLEPGTE-PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 Q+ +PG+ P+G PG K +PG G RG + G RG+ G G G G QG Sbjct: 1097 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152 Score = 128 bits (322), Expect = 3e-29 Identities = 82/213 (38%), Positives = 102/213 (47%), Gaps = 13/213 (6%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG GPPG G G PG +GFPG G PG KG +G+ G G G G QG PGR G Sbjct: 507 GDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG------PTGLPGPKGER 1185 G G RGL G PG GP G G GA G G GPPG++G GLPGPKG Sbjct: 567 GLPGARGLTGN---PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G+ G+P + + + P + ++ E G P G G + Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG--PPGPTGFQGLPG 681 Query: 1246 VPGEWGRGGRHLEG--RGEPGAVGQMGSPGQQG 1276 PG G GG+ + G+PGAVG +G G++G Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714 Score = 127 bits (320), Expect = 5e-29 Identities = 83/209 (39%), Positives = 98/209 (46%), Gaps = 18/209 (8%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 G GP GP G+PG G G QG PG RG PG G G G+PG G PG+ G+ G Sbjct: 330 GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389 Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 G G +G G +G G GPPGP G G+ GA GT G PG GPTG PG G G Sbjct: 390 GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT---PGAKGPTGSPGTSGPPGSA 446 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 G P S Q D P +P + + P EP G G + PG Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGD-------PGVPGFKGEAGPKGEP-GPHGIQGPIGPPG 498 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 E G+ G RG+PG VG G G++GA Sbjct: 499 EEGKRG----PRGDPGTVGPPGPVGERGA 523 Score = 127 bits (319), Expect = 7e-29 Identities = 89/226 (39%), Positives = 109/226 (48%), Gaps = 27/226 (11%) Query: 1071 PGPPGP---------QGPPGLPGRNGTPGEQGFPGP---RGPPGVKGEKGDHGLPGLQGH 1118 PG PGP +GPPG PG +G PG G PG G PG +G G GLPGL+GH Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301 Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178 GH+ GL+GPKG G G+ G GP GP G G G RG GER G +GP G Sbjct: 302 RGHK------GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGER---GRLGPQGA 352 Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQ---ASHVSKFDSFHENTRPPMPILEQKLEPGTE-P 1234 PG +G G G+P + L S + K ++ R P Q+ E G P Sbjct: 353 PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412 Query: 1235 LGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278 +GSPG G G +G G G PG+ G GSPG QG++ Sbjct: 413 VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458 Score = 127 bits (319), Expect = 7e-29 Identities = 84/209 (40%), Positives = 103/209 (49%), Gaps = 11/209 (5%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG QGP G G G PGE G PGP G G++G+ G GLPG +G G G PG G Sbjct: 576 GNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G G RG G G GP GP G G+AG R GE+GPPG G GLPGP G GE G+P Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGER---GEQGPPGPTGFQGLPGPPGPPGEGGKP 692 Query: 1192 --QSLATLYQLVSQASHVSKFDSFHENTRPPMPIL--EQKLEPGTEPLGSPGTRSKALVP 1247 Q + V + + E P + L E+ + G P G G+ + P Sbjct: 693 GDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTP 752 Query: 1248 GEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G+ G G +G PG G G+PG +G Sbjct: 753 GDTGPPGL----QGMPGERGIAGTPGPKG 777 Score = 126 bits (317), Expect = 1e-28 Identities = 86/227 (37%), Positives = 103/227 (45%), Gaps = 31/227 (13%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPR---------GPPGVKGEKGDHGLPGLQGHPG 1120 T GPPGP G G PG G PG G PGP+ G G KG +GD G PG G PG Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570 Query: 1121 HQGIPGRVGLQGPKGM---RGLEGTAGLPGPPGPRGFQ------GMAGARGTSGERGPPG 1171 +G+ G G+QGP+G G G G PGPPG G + G+ G +G+SG+ G PG Sbjct: 571 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG 630 Query: 1172 TVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229 G G+PG +G G+ GE P L + PP P Q L Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG----------PPGPTGFQGLP 680 Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 P G G VPG+ G G L RGE G G+ G PG G Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVG-PLGPRGERGNPGERGEPGITG 726 Score = 125 bits (315), Expect = 2e-28 Identities = 79/214 (36%), Positives = 96/214 (44%), Gaps = 33/214 (15%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 +PG G G PGLPG G G +G GP+ G PG KGE G G G G G +G+PG Sbjct: 283 SPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPG 342 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP+G G G G+PG PGP G G+ G+ G G G G GPTG GP+G +G Sbjct: 343 ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQG 402 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246 ++GE T PP P+ L G+PG + Sbjct: 403 QRGE--------------------------TGPPGPVGSPGLPGAIGTDGTPGAKGPTGS 436 Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280 PG G G G PG+ G GS G QG Q Sbjct: 437 PGTSGPPG----SAGPPGSPGPQGSTGPQGIRGQ 466 Score = 125 bits (315), Expect = 2e-28 Identities = 82/236 (34%), Positives = 108/236 (45%), Gaps = 30/236 (12%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIPGR 1127 PG PGP GP G+PG +G PG G G GP G +G +G G G G P G G+PG Sbjct: 362 PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421 Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187 +G G G +G G+ G GPPG G G G +G++G +G G G G+PG KGE G Sbjct: 422 IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481 Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENT-RPPMPILEQKLE-----PGTE-------- 1233 KGEP + + T PP P+ E+ PG++ Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541 Query: 1234 -----PLGSPGTRSKALVPGEWGR----GGRHLEG----RGEPGAVGQMGSPGQQG 1276 P+GS G + PG G G R L G +G G +G +G+PG+ G Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDG 597 Score = 124 bits (310), Expect = 8e-28 Identities = 90/236 (38%), Positives = 114/236 (48%), Gaps = 36/236 (15%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PGP GPPG G G G +G PGPRGP G+ GE G G PG G PGH PG GL Sbjct: 129 GRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188 Query: 1132 GP--KGMRGLEGTAGL----------PGPPGPRGFQGMAGARGTSGERGPP--------- 1170 P M GL+ +GL GP GPRG QG+ G +G +G GPP Sbjct: 189 RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPM 248 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK-FDSFHENTRPPMPILE---- 1225 G +G G GP G+ GE GEP ++ S ++ F P +P L+ Sbjct: 249 GPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG-----APGLPGLKGHRG 303 Query: 1226 -QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP---GAVGQMGSPGQQGA 1277 + LE +G+PG++ +A G G G L RG P G +G G+PGQ+GA Sbjct: 304 HKGLEGPKGEVGAPGSKGEAGPTGPMGAMG-PLGPRGMPGERGRLGPQGAPGQRGA 358 Score = 123 bits (309), Expect = 1e-27 Identities = 63/134 (47%), Positives = 75/134 (55%), Gaps = 9/134 (6%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRG---------PPGVKGEKGDHGLPGLQG 1117 S PG PGP G PG G+ G PG +G GP G P G +G+KGDHG G +G Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 GH+G G GL GP G G +G+AG+PGP GPRG G G G G GP G +GP G Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG 1200 Query: 1178 LPGPKGERGEKGEP 1191 + G GE G +G P Sbjct: 1201 VRGSVGEAGPEGPP 1214 Score = 122 bits (307), Expect = 2e-27 Identities = 90/236 (38%), Positives = 105/236 (44%), Gaps = 30/236 (12%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGP---PGLPGRNGTPGEQGFPGPRGPPGVKG 1105 P G+ P S+ G PGP+GP G PGR+G GE+G G GP G+ G Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080 Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165 +G G PG G PG G G G +GP G G G GLPGP GPRG +G G RG G Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140 Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225 ++G G G GLPGP G GE+G A F PP P+ Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQG-------------SAGIPGPFGP----RGPPGPVGP 1183 Query: 1226 QKLE--PG-TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 E PG P+G PG R GE G G GEPG G G PG A+ Sbjct: 1184 SGKEGNPGPLGPIGPPGVRGSV---GEAGPEG----PPGEPGPPGPPGPPGHLTAA 1232 Score = 121 bits (304), Expect = 4e-27 Identities = 90/249 (36%), Positives = 109/249 (43%), Gaps = 39/249 (15%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGH----- 1118 SS PG PG G G+PG+ G PG+ G GP GP PG+ GE+G+ G PG G Sbjct: 622 SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG 681 Query: 1119 ----------PGHQGIPGRVGLQGPKGMRGLEGT---------AGLPGPPGPRGFQGMAG 1159 PG QG+PG G GP G RG G GLPG G G G G Sbjct: 682 PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHEN--- 1216 +G+ G G PG GP GL G GERG G P + + + + + Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801 Query: 1217 -TRPPMPI--LEQKLEPGTEPL-GSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVG 1267 PP P +K EPG L G PG+R GE G G G G+PG G Sbjct: 802 PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861 Query: 1268 QMGSPGQQG 1276 + G PGQ+G Sbjct: 862 EPGEPGQKG 870 Score = 120 bits (302), Expect = 6e-27 Identities = 87/246 (35%), Positives = 104/246 (42%), Gaps = 36/246 (14%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQ------GPPGLPGRNGTPGEQGFPGPRGPP- 1101 P+ G+T P + G PGP+ G G G G G +G PGP GPP Sbjct: 748 PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807 Query: 1102 --GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159 G GEKG+ G GL G PG +G PG G GP G G G G G PG +G G G Sbjct: 808 PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG 867 Query: 1160 ARGTSGERGP------PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 +G +G GP PG GP G+PG KG RG +G P + + F Sbjct: 868 QKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGA--------------TGFPGS 913 Query: 1214 HENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMG 1270 PP P PG PLG PG + G+ G GR G PG G G Sbjct: 914 AGRVGPPGP----AGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG 969 Query: 1271 SPGQQG 1276 PG+ G Sbjct: 970 DPGEDG 975 Score = 117 bits (294), Expect = 5e-26 Identities = 94/261 (36%), Positives = 110/261 (42%), Gaps = 41/261 (15%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNG---TPGEQGF---PGPRGP-- 1100 P SR GE P + G PG +G PG PG+ G +PG QG PGP GP Sbjct: 833 PGSR-GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG 891 Query: 1101 -PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159 PG+KG +G G PG G PG GRVG GP G G G G PG GP G +G G Sbjct: 892 VPGLKGGRGTQGPPGATGFPGS---AGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPG 948 Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENT 1217 + G G+RGP GP G PG KG+ GE G+ P Q V E Sbjct: 949 SHGRVGDRGP---AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERG 1005 Query: 1218 RPPMP-------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH-------- 1256 P +P K PG P+G PG+ PG G G Sbjct: 1006 MPGLPGPAGTPGKVGPTGATGDKGPPG--PVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063 Query: 1257 LEGRGEPGAVGQMGSPGQQGA 1277 + RG+ G G G PG QGA Sbjct: 1064 VGERGDRGDPGPAGLPGSQGA 1084 Score = 115 bits (289), Expect = 2e-25 Identities = 85/226 (37%), Positives = 99/226 (43%), Gaps = 38/226 (16%) Query: 1067 SSETPGPPGPQ---------GPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPG 1114 S PGP G Q GP G G G PGE G PG R G PGV+G +G G G Sbjct: 532 SDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLG 591 Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGL---EGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171 G G G PG +G++G G GL +G++G PG PG G G+ G RG G+ G G Sbjct: 592 APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG 651 Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231 GP G PG GERGE+G P F PP P E +PG Sbjct: 652 PSGPVGPPGLAGERGEQGPPGP-----------------TGFQGLPGPPGPPGEGG-KPG 693 Query: 1232 TEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 + + G PG GE G G RGEPG G G G G Sbjct: 694 DQGVPGDPGAVGPLGPRGERGNPGE----RGEPGITGLPGEKGMAG 735 Score = 85.5 bits (210), Expect = 3e-16 Identities = 85/262 (32%), Positives = 101/262 (38%), Gaps = 60/262 (22%) Query: 1033 IVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ 1092 I+C + C P + GE CP S+TPG G N G Sbjct: 69 ILCDKIECQDVLDCADPVTPPGECCPV-------CSQTPG-----------GGNTNFG-- 108 Query: 1093 GFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR 1152 +G KG G PGL P GI GR G GP G +G G G G PGPR Sbjct: 109 -----------RGRKGQKGEPGLV--PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPR 155 Query: 1153 GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDS 1212 G QG+ G G G+ G PG G PGP G P S A + L ++ S+ Sbjct: 156 GPQGIDGEPGVPGQPGAPGPPGHPSHPGPDG----LSRPFS-AQMAGLDEKSGLGSQVGL 210 Query: 1213 FHENTRPPMPILEQKL--------------EPGTE----PLGSPGTRSKALVPGEWGRGG 1254 + P P Q L EPG P+GS G PGE G G Sbjct: 211 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG 270 Query: 1255 RHLEGRGEPGAVGQMGSPGQQG 1276 R+ G PG VG GSPG +G Sbjct: 271 RN----GNPGEVGFAGSPGARG 288 Score = 57.4 bits (137), Expect = 9e-08 Identities = 51/165 (30%), Positives = 65/165 (39%), Gaps = 44/165 (26%) Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 +G G +G PG V + G+RG G AG PG GPRG +G +G G RGP G G Sbjct: 109 RGRKGQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGERG---PKGRPGPRGPQGIDGE 163 Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235 G+PG G G G P SH PG + L Sbjct: 164 PGVPGQPGAPGPPGHP-------------SH-----------------------PGPDGL 187 Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280 P + A + + G G + PG+VG +G G QG Q Sbjct: 188 SRPFSAQMAGLDEKSGLGS---QVGLMPGSVGPVGPRGPQGLQGQ 229 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 141 bits (355), Expect = 5e-33 Identities = 92/225 (40%), Positives = 107/225 (47%), Gaps = 43/225 (19%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKGDHGLPGLQG 1117 S+ PGPPGP GP G G G G+ G PG P GPPG KGE GD G G +G Sbjct: 910 SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 PG QG+ G+ G+ G G RG G GLPGP G G QG GA SG+RGPPG VGP G Sbjct: 970 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA---SGDRGPPGPVGPPG 1026 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP-----MPILEQKLEPGT 1232 L GP GE G +G P + PP + + E G Sbjct: 1027 LTGPAGEPGREGSPGA-----------------------DGPPGRDGAAGVKGDRGETGA 1063 Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 +G+PG PG G G+ + RGE GA G MG G GA Sbjct: 1064 --VGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGA 1105 Score = 134 bits (338), Expect = 4e-31 Identities = 95/262 (36%), Positives = 118/262 (45%), Gaps = 37/262 (14%) Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGPQGP------PGLPGRNGTPGEQGFPGPRGPP 1101 LP R G T PA + + PGP GP GP PG PG G GE G G RGP Sbjct: 328 LPGER-GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386 Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR--------- 1152 G +G +G+ G PG G G G PG G+ G KG G G AG PG PGPR Sbjct: 387 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446 Query: 1153 ---------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---RGEKGEPQSLATLYQL 1200 G G+AG +G G +G PG GP G PGP GE RG +GEP + + Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506 Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWG-RGGRHLE 1258 + + ++ + P ++ G P G+ G + PGE G G R L Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR---PGEPGLPGARGLT 563 Query: 1259 GR----GEPGAVGQMGSPGQQG 1276 GR G G VG G+PG+ G Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDG 585 Score = 134 bits (338), Expect = 4e-31 Identities = 99/255 (38%), Positives = 113/255 (44%), Gaps = 58/255 (22%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVKGEKG 1108 +DGET A GPPGP GP G G G PG GF PGP GPPG G+ G Sbjct: 634 KDGETGAA------------GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681 Query: 1109 DHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGT---AGLPGPPGPRG 1153 D G+PG +G PG +G PG GLQGP+G+ G GT G GP GP G Sbjct: 682 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 741 Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 QG G +G GERG G GP G G GE+G +G P D Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-----------------DGG 784 Query: 1214 HENTRP-----PMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG--RGEPGA 1265 T P P +K E G P GS G R PGE G G G PGA Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETGPPGPAGFAGPPGA 841 Query: 1266 VGQMGSPGQQGASTQ 1280 GQ G+ G+QG + Q Sbjct: 842 DGQPGAKGEQGEAGQ 856 Score = 134 bits (336), Expect = 7e-31 Identities = 91/246 (36%), Positives = 106/246 (43%), Gaps = 33/246 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 PA GE S PGPPGP G G PG G PGE G PG GP G +G G Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA-------- 1160 + G PG QG G +G+PG G GPKG G G G GPPG +G G GA Sbjct: 706 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765 Query: 1161 -RGTSGERGPPGT---------VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210 RG GE+GP G GP G PGP G GEKGE ++ + + Sbjct: 766 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825 Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270 + T PP P G PG + GE G G+ + G PG G G Sbjct: 826 E-----TGPPGP---------AGFAGPPGADGQPGAKGEQGEAGQKGDA-GAPGPQGPSG 870 Query: 1271 SPGQQG 1276 +PG QG Sbjct: 871 APGPQG 876 Score = 134 bits (336), Expect = 7e-31 Identities = 97/274 (35%), Positives = 114/274 (41%), Gaps = 52/274 (18%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 GE P + + + PG G GPPG G G PG G PG +G G G+KGD G P Sbjct: 804 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGL------------------PGPPGPRGFQ 1155 G QG G G G G+ GPKG RG +G G PGPPGP G Sbjct: 864 GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923 Query: 1156 GMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP--------QSLATLYQLVSQASHV 1207 G G +G G+ GPPG G GL GP G GEKGEP + L Q V Sbjct: 924 GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983 Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-------------PLGSPGTRSKALVPGEWGR-- 1252 E P +P EPG + P+G PG A PG G Sbjct: 984 GLPGQRGERGFPGLP--GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041 Query: 1253 --------GGRHLEG-RGEPGAVGQMGSPGQQGA 1277 G ++G RGE GAVG G+PG G+ Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Score = 132 bits (331), Expect = 3e-30 Identities = 94/248 (37%), Positives = 104/248 (41%), Gaps = 60/248 (24%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLP---------------GRNGTPGEQGFPGPR 1098 GE V S S G PGP GP GLP G +G PG G PGP Sbjct: 300 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 359 Query: 1099 GP---------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 GP PG KGE G G G +G G +G PG G GP G G GT G+PG Sbjct: 360 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 G G G+AGA G G RGPPG G TG GPKG+ GE G Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG-------------------- 459 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQM 1269 I K E G P G PG PG G G+ RGEPG VG + Sbjct: 460 -------------IAGFKGEQG--PKGEPGPAGPQGAPGPAGEEGKR-GARGEPGGVGPI 503 Query: 1270 GSPGQQGA 1277 G PG++GA Sbjct: 504 GPPGERGA 511 Score = 130 bits (326), Expect = 1e-29 Identities = 87/221 (39%), Positives = 98/221 (44%), Gaps = 37/221 (16%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPGP G PG G G PGE G PG GP G +G G G PG G G G G G Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------------GTSGERGPPGTVGPTGLP 1179 GP+G RG GT GLPG G RG+ G+ GA+ G+ GE G PG +GP GLP Sbjct: 270 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329 Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239 G +G G G A+ D PP P+ P G PG Sbjct: 330 GERGRTGPAG--------------AAGARGNDGQPGPAGPPGPV---------GPAGGPG 366 Query: 1240 TRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278 GE G G R EG +G G G GSPG GAS Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 407 Score = 127 bits (320), Expect = 5e-29 Identities = 83/212 (39%), Positives = 96/212 (45%), Gaps = 17/212 (8%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP G PG G G G++G PGP GPPG+ G G+ PG +G PG G PGR G Sbjct: 995 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGREGSPGADGPPGRDGA 1051 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G KG RG G G PG PGP G G AG G G+RG G GP G GP G RG +G Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1111 Query: 1191 PQSLATLYQLVSQASHVSK----FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246 + K F PP P +Q + P G G R Sbjct: 1112 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ---GASGPAGPSGPRGP--- 1165 Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 PG G G+ G G G +G PG +G S Sbjct: 1166 PGPVGPSGKD----GANGIPGPIGPPGPRGRS 1193 Score = 127 bits (319), Expect = 7e-29 Identities = 85/211 (40%), Positives = 101/211 (47%), Gaps = 27/211 (12%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G +GP G PG++G G G GP GP G GEKG+ G PG G G +G PG G Sbjct: 768 GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185 GP G G G G G PG +G QG AG +G +G GP PG GPTG+ GPKG R Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G P + A V S + N PP P PG P G G + Sbjct: 888 GAQGPPGATG----FPGAAGRVGPPGS-NGNPGPPGP-------PG--PSGKDGPKG--- 930 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G+ G GR GEPG G G PG++G Sbjct: 931 ARGDSGPPGR----AGEPGLQGPAGPPGEKG 957 Score = 125 bits (314), Expect = 3e-28 Identities = 84/213 (39%), Positives = 95/213 (44%), Gaps = 20/213 (9%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPG 1126 T GP G GP G PG G PG QG PG RG G+ KG++GD G G +G PG G G Sbjct: 727 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 786 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G G G GPPGP G G GA G GE GPPG G G PG G+ G Sbjct: 787 LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKAL 1245 KGE Q K D+ + P + G T P G+ G + Sbjct: 847 AKGE------------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 894 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 G G GR G PG+ G G PG G S Sbjct: 895 ATGFPGAAGRV----GPPGSNGNPGPPGPPGPS 923 Score = 125 bits (313), Expect = 3e-28 Identities = 86/220 (39%), Positives = 97/220 (44%), Gaps = 24/220 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---GPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 PGP GPQG PG G G G +G P GP GPPG +G G+ G PG G G +G PG Sbjct: 473 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532 Query: 1128 ---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 GL GPKG G G G PG PG RG G G G G+ GP G G G PGP G Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 592 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--EPGTEPL-GSPGTR 1241 +G +G+P V F P E+ L PG L G G Sbjct: 593 QGARGQP--------------GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638 Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 A PG G G E +G PG G G PG G +G Sbjct: 639 GAAGPPGPAGPAGERGE-QGAPGPSGFQGLPGPPGPPGEG 677 Score = 124 bits (310), Expect = 8e-28 Identities = 85/219 (38%), Positives = 100/219 (45%), Gaps = 23/219 (10%) Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 S PG G GPPG G G PG GFPGP+G G G+ G+ GLPG G G G G Sbjct: 578 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637 Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE------RGPPGTVGPTGLPGP 1181 G GP G G G G G PGP GFQG+ G G GE +G PG G GL GP Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 697 Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241 +GERG GE S +Q + T P PG + G PG + Sbjct: 698 RGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ--GPPGLQ 749 Query: 1242 SKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQG 1276 +PGE RG + G RG+ G G G+PG+ G Sbjct: 750 G---MPGE--RGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783 Score = 122 bits (306), Expect = 2e-27 Identities = 80/233 (34%), Positives = 101/233 (43%), Gaps = 31/233 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P+ +DG P S G PG QGP G PG G PG+ G G GPPG +G G Sbjct: 922 PSGKDG---PKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168 G+ GL G G +G PG G G G +G G +G GPPGP G G+ G G G G Sbjct: 979 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 1038 Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228 PG GP G G G +G++GE ++ P P Sbjct: 1039 SPGADGPPGRDGAAGVKGDRGETGAVGA----------------------PGAPGPPGSP 1076 Query: 1229 EPGTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 P P G G R +A G G G R ++G +G G G+ G PG++G Sbjct: 1077 GP-AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1128 Score = 120 bits (302), Expect = 6e-27 Identities = 82/214 (38%), Positives = 97/214 (45%), Gaps = 9/214 (4%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG G GLPG++G G G PGP GP G +GE+G G G QG PG G PG G Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185 G +G+ G G GL GP G RGF G G+ G G +GP PGT GP G GP G Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244 G +G P + + K D + P + G T P+G PG Sbjct: 741 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800 Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 GE G G RG PG G+ G PG G Sbjct: 801 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834 Score = 120 bits (300), Expect = 1e-26 Identities = 101/317 (31%), Positives = 123/317 (38%), Gaps = 80/317 (25%) Query: 1033 IVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGP------------------- 1073 ++C D ++ + C P GE CP + + +S PGP Sbjct: 62 VLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGP 121 Query: 1074 PGPQGP------------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG---- 1111 PGPQGP PG GR+G PG G PGP GPPG G G G Sbjct: 122 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181 Query: 1112 -----------------LPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---GPPGP 1151 + G G G +G PG G GP+G +G G G P GP GP Sbjct: 182 QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 241 Query: 1152 RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFD 1211 RG G G G GE G PG G G PGP+G RG G P L + + Sbjct: 242 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP----GLPGVKGHRGYPGLDG 297 Query: 1212 SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-------GGRHLEGR---- 1260 + E P + + PG GSPG +PGE GR G R +G+ Sbjct: 298 AKGEAGAP--GVKGESGSPGEN--GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353 Query: 1261 GEPGAVGQMGSPGQQGA 1277 G PG VG G PG GA Sbjct: 354 GPPGPVGPAGGPGFPGA 370 Score = 117 bits (292), Expect = 9e-26 Identities = 83/208 (39%), Positives = 92/208 (44%), Gaps = 42/208 (20%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG G PGLPG G G G GP+G G G G+ G PG G G +G PG +G Sbjct: 546 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 605 Query: 1132 GPKGMRGLEGTAG---LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GPKG G G AG LPG P G RG G+ G G GP G GP GERGE+ Sbjct: 606 GPKGANGEPGKAGEKGLPGAP---------GLRGLPGKDGETGAAGPPGPAGPAGERGEQ 656 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 G P F PP P PG G PG + VPG Sbjct: 657 GAPGP-----------------SGFQGLPGPPGP-------PGEG--GKPGDQG---VPG 687 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 E G G + RGE G G+ GSPG QG Sbjct: 688 EAGAPGL-VGPRGERGFPGERGSPGAQG 714 Score = 101 bits (251), Expect = 5e-21 Identities = 56/120 (46%), Positives = 62/120 (51%), Gaps = 6/120 (5%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP GP GP G G QG GPRG G GE G+ GL G +G G QG+PG G Sbjct: 1095 GPMGPSGPA------GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G +G G G +G GPPGP G G GA G G GPPG G +G GP G G G P Sbjct: 1149 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208 Score = 73.2 bits (178), Expect = 2e-12 Identities = 45/116 (38%), Positives = 49/116 (42%), Gaps = 24/116 (20%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP G +G G PG G G +GF G +G PG G GD G G G G +G PG VG Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1172 Query: 1132 G------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 G P G RG G G GPP G G GPPG GP Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPP------------GNPGPPGPPGPPGP 1216 Score = 69.3 bits (168), Expect = 2e-11 Identities = 44/111 (39%), Positives = 53/111 (47%), Gaps = 6/111 (5%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 +S GP GP+GPPG G +G G G PGP GPPG +G G+ G G G+PG G PG Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212 Query: 1127 RVGLQGPKGMRGLEGTAGL-PGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G G+ + AGL P GP Q M + G R V T Sbjct: 1213 PPG----PGI-DMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDAT 1258 Score = 47.4 bits (111), Expect = 9e-05 Identities = 24/57 (42%), Positives = 27/57 (47%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG 1105 P+ G P S ++ PGP GP GP G G G G G PGP GPPG G Sbjct: 1159 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/60 (43%), Positives = 27/60 (45%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 PA G P S G PGP GPPG GR+G G G PG GPPG G G Sbjct: 1156 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 141 bits (355), Expect = 5e-33 Identities = 92/225 (40%), Positives = 107/225 (47%), Gaps = 43/225 (19%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKGDHGLPGLQG 1117 S+ PGPPGP GP G G G G+ G PG P GPPG KGE GD G G +G Sbjct: 841 SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900 Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177 PG QG+ G+ G+ G G RG G GLPGP G G QG GA SG+RGPPG VGP G Sbjct: 901 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA---SGDRGPPGPVGPPG 957 Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP-----MPILEQKLEPGT 1232 L GP GE G +G P + PP + + E G Sbjct: 958 LTGPAGEPGREGSPGA-----------------------DGPPGRDGAAGVKGDRGETGA 994 Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 +G+PG PG G G+ + RGE GA G MG G GA Sbjct: 995 --VGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGA 1036 Score = 134 bits (338), Expect = 4e-31 Identities = 95/262 (36%), Positives = 118/262 (45%), Gaps = 37/262 (14%) Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGPQGP------PGLPGRNGTPGEQGFPGPRGPP 1101 LP R G T PA + + PGP GP GP PG PG G GE G G RGP Sbjct: 259 LPGER-GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR--------- 1152 G +G +G+ G PG G G G PG G+ G KG G G AG PG PGPR Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 1153 ---------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---RGEKGEPQSLATLYQL 1200 G G+AG +G G +G PG GP G PGP GE RG +GEP + + Sbjct: 378 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437 Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWG-RGGRHLE 1258 + + ++ + P ++ G P G+ G + PGE G G R L Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR---PGEPGLPGARGLT 494 Query: 1259 GR----GEPGAVGQMGSPGQQG 1276 GR G G VG G+PG+ G Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDG 516 Score = 134 bits (338), Expect = 4e-31 Identities = 99/255 (38%), Positives = 113/255 (44%), Gaps = 58/255 (22%) Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVKGEKG 1108 +DGET A GPPGP GP G G G PG GF PGP GPPG G+ G Sbjct: 565 KDGETGAA------------GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612 Query: 1109 DHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGT---AGLPGPPGPRG 1153 D G+PG +G PG +G PG GLQGP+G+ G GT G GP GP G Sbjct: 613 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 672 Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213 QG G +G GERG G GP G G GE+G +G P D Sbjct: 673 AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-----------------DGG 715 Query: 1214 HENTRP-----PMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG--RGEPGA 1265 T P P +K E G P GS G R PGE G G G PGA Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETGPPGPAGFAGPPGA 772 Query: 1266 VGQMGSPGQQGASTQ 1280 GQ G+ G+QG + Q Sbjct: 773 DGQPGAKGEQGEAGQ 787 Score = 134 bits (336), Expect = 7e-31 Identities = 91/246 (36%), Positives = 106/246 (43%), Gaps = 33/246 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 PA GE S PGPPGP G G PG G PGE G PG GP G +G G Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA-------- 1160 + G PG QG G +G+PG G GPKG G G G GPPG +G G GA Sbjct: 637 ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696 Query: 1161 -RGTSGERGPPGT---------VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210 RG GE+GP G GP G PGP G GEKGE ++ + + Sbjct: 697 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756 Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270 + T PP P G PG + GE G G+ + G PG G G Sbjct: 757 E-----TGPPGP---------AGFAGPPGADGQPGAKGEQGEAGQKGDA-GAPGPQGPSG 801 Query: 1271 SPGQQG 1276 +PG QG Sbjct: 802 APGPQG 807 Score = 134 bits (336), Expect = 7e-31 Identities = 97/274 (35%), Positives = 114/274 (41%), Gaps = 52/274 (18%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113 GE P + + + PG G GPPG G G PG G PG +G G G+KGD G P Sbjct: 735 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794 Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGL------------------PGPPGPRGFQ 1155 G QG G G G G+ GPKG RG +G G PGPPGP G Sbjct: 795 GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854 Query: 1156 GMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP--------QSLATLYQLVSQASHV 1207 G G +G G+ GPPG G GL GP G GEKGEP + L Q V Sbjct: 855 GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914 Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-------------PLGSPGTRSKALVPGEWGR-- 1252 E P +P EPG + P+G PG A PG G Sbjct: 915 GLPGQRGERGFPGLP--GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972 Query: 1253 --------GGRHLEG-RGEPGAVGQMGSPGQQGA 1277 G ++G RGE GAVG G+PG G+ Sbjct: 973 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Score = 132 bits (331), Expect = 3e-30 Identities = 94/248 (37%), Positives = 104/248 (41%), Gaps = 60/248 (24%) Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLP---------------GRNGTPGEQGFPGPR 1098 GE V S S G PGP GP GLP G +G PG G PGP Sbjct: 231 GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 290 Query: 1099 GP---------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 GP PG KGE G G G +G G +G PG G GP G G GT G+PG Sbjct: 291 GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350 Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209 G G G+AGA G G RGPPG G TG GPKG+ GE G Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG-------------------- 390 Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQM 1269 I K E G P G PG PG G G+ RGEPG VG + Sbjct: 391 -------------IAGFKGEQG--PKGEPGPAGPQGAPGPAGEEGKR-GARGEPGGVGPI 434 Query: 1270 GSPGQQGA 1277 G PG++GA Sbjct: 435 GPPGERGA 442 Score = 130 bits (326), Expect = 1e-29 Identities = 87/221 (39%), Positives = 98/221 (44%), Gaps = 37/221 (16%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GPPGP G PG G G PGE G PG GP G +G G G PG G G G G G Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------------GTSGERGPPGTVGPTGLP 1179 GP+G RG GT GLPG G RG+ G+ GA+ G+ GE G PG +GP GLP Sbjct: 201 GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260 Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239 G +G G G A+ D PP P+ P G PG Sbjct: 261 GERGRTGPAG--------------AAGARGNDGQPGPAGPPGPV---------GPAGGPG 297 Query: 1240 TRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278 GE G G R EG +G G G GSPG GAS Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338 Score = 127 bits (320), Expect = 5e-29 Identities = 83/212 (39%), Positives = 96/212 (45%), Gaps = 17/212 (8%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 PG PGP G PG G G G++G PGP GPPG+ G G+ PG +G PG G PGR G Sbjct: 926 PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGREGSPGADGPPGRDGA 982 Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190 G KG RG G G PG PGP G G AG G G+RG G GP G GP G RG +G Sbjct: 983 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1042 Query: 1191 PQSLATLYQLVSQASHVSK----FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246 + K F PP P +Q + P G G R Sbjct: 1043 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ---GASGPAGPSGPRGP--- 1096 Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 PG G G+ G G G +G PG +G S Sbjct: 1097 PGPVGPSGKD----GANGIPGPIGPPGPRGRS 1124 Score = 127 bits (319), Expect = 7e-29 Identities = 85/211 (40%), Positives = 101/211 (47%), Gaps = 27/211 (12%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G G +GP G PG++G G G GP GP G GEKG+ G PG G G +G PG G Sbjct: 699 GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185 GP G G G G G PG +G QG AG +G +G GP PG GPTG+ GPKG R Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245 G +G P + A V S + N PP P PG P G G + Sbjct: 819 GAQGPPGATG----FPGAAGRVGPPGS-NGNPGPPGP-------PG--PSGKDGPKG--- 861 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 G+ G GR GEPG G G PG++G Sbjct: 862 ARGDSGPPGR----AGEPGLQGPAGPPGEKG 888 Score = 125 bits (314), Expect = 3e-28 Identities = 84/213 (39%), Positives = 95/213 (44%), Gaps = 20/213 (9%) Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPG 1126 T GP G GP G PG G PG QG PG RG G+ KG++GD G G +G PG G G Sbjct: 658 TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 717 Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 G GP G G G G GPPGP G G GA G GE GPPG G G PG G+ G Sbjct: 718 LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 777 Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKAL 1245 KGE Q K D+ + P + G T P G+ G + Sbjct: 778 AKGE------------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 825 Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278 G G GR G PG+ G G PG G S Sbjct: 826 ATGFPGAAGRV----GPPGSNGNPGPPGPPGPS 854 Score = 125 bits (313), Expect = 3e-28 Identities = 86/220 (39%), Positives = 97/220 (44%), Gaps = 24/220 (10%) Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---GPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 PGP GPQG PG G G G +G P GP GPPG +G G+ G PG G G +G PG Sbjct: 404 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 463 Query: 1128 ---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184 GL GPKG G G G PG PG RG G G G G+ GP G G G PGP G Sbjct: 464 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 523 Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--EPGTEPL-GSPGTR 1241 +G +G+P V F P E+ L PG L G G Sbjct: 524 QGARGQP--------------GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569 Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281 A PG G G E +G PG G G PG G +G Sbjct: 570 GAAGPPGPAGPAGERGE-QGAPGPSGFQGLPGPPGPPGEG 608 Score = 124 bits (310), Expect = 8e-28 Identities = 85/219 (38%), Positives = 100/219 (45%), Gaps = 23/219 (10%) Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127 S PG G GPPG G G PG GFPGP+G G G+ G+ GLPG G G G G Sbjct: 509 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568 Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE------RGPPGTVGPTGLPGP 1181 G GP G G G G G PGP GFQG+ G G GE +G PG G GL GP Sbjct: 569 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 628 Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241 +GERG GE S +Q + T P PG + G PG + Sbjct: 629 RGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ--GPPGLQ 680 Query: 1242 SKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQG 1276 +PGE RG + G RG+ G G G+PG+ G Sbjct: 681 G---MPGE--RGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714 Score = 122 bits (306), Expect = 2e-27 Identities = 80/233 (34%), Positives = 101/233 (43%), Gaps = 31/233 (13%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 P+ +DG P S G PG QGP G PG G PG+ G G GPPG +G G Sbjct: 853 PSGKDG---PKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909 Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168 G+ GL G G +G PG G G G +G G +G GPPGP G G+ G G G G Sbjct: 910 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969 Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228 PG GP G G G +G++GE ++ P P Sbjct: 970 SPGADGPPGRDGAAGVKGDRGETGAVGA----------------------PGAPGPPGSP 1007 Query: 1229 EPGTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQG 1276 P P G G R +A G G G R ++G +G G G+ G PG++G Sbjct: 1008 GP-AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1059 Score = 120 bits (302), Expect = 6e-27 Identities = 82/214 (38%), Positives = 97/214 (45%), Gaps = 9/214 (4%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG G GLPG++G G G PGP GP G +GE+G G G QG PG G PG G Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185 G +G+ G G GL GP G RGF G G+ G G +GP PGT GP G GP G Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671 Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244 G +G P + + K D + P + G T P+G PG Sbjct: 672 GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731 Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276 GE G G RG PG G+ G PG G Sbjct: 732 GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765 Score = 118 bits (296), Expect = 3e-26 Identities = 83/227 (36%), Positives = 95/227 (41%), Gaps = 48/227 (21%) Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128 GPPGPQGP G G G GE+G PGPRG G G G+ G PG G PG G+ G Sbjct: 51 GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110 Query: 1129 G------------------LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170 +QGP G G G G G PGP+GFQG G G G GP Sbjct: 111 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 170 Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230 G GP G PG G+ GE G+P PP P + P Sbjct: 171 GPRGPPGPPGKPGDDGEAGKPGKAG--------------------ERGPPGPQGARGF-P 209 Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277 GT G PG + PG G G G PG G+ GSPG+ G+ Sbjct: 210 GTP--GLPGVKGHRGYPGLDGAKGE----AGAPGVKGESGSPGENGS 250 Score = 117 bits (292), Expect = 9e-26 Identities = 83/208 (39%), Positives = 92/208 (44%), Gaps = 42/208 (20%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 G PG G PGLPG G G G GP+G G G G+ G PG G G +G PG +G Sbjct: 477 GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536 Query: 1132 GPKGMRGLEGTAG---LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188 GPKG G G AG LPG P G RG G+ G G GP G GP GERGE+ Sbjct: 537 GPKGANGEPGKAGEKGLPGAP---------GLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587 Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248 G P F PP P PG G PG + VPG Sbjct: 588 GAPGP-----------------SGFQGLPGPPGP-------PGEG--GKPGDQG---VPG 618 Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276 E G G + RGE G G+ GSPG QG Sbjct: 619 EAGAPGL-VGPRGERGFPGERGSPGAQG 645 Score = 101 bits (251), Expect = 5e-21 Identities = 56/120 (46%), Positives = 62/120 (51%), Gaps = 6/120 (5%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP GP GP G G QG GPRG G GE G+ GL G +G G QG+PG G Sbjct: 1026 GPMGPSGPA------GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079 Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191 G +G G G +G GPPGP G G GA G G GPPG G +G GP G G G P Sbjct: 1080 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139 Score = 90.5 bits (223), Expect = 9e-18 Identities = 75/243 (30%), Positives = 89/243 (36%), Gaps = 84/243 (34%) Query: 1066 CSSETPGPPGPQGPPGLPGR-NGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124 C + PGP+G G PG G +G PGP+GP G +G +GD G G +G PG Sbjct: 23 CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP--- 79 Query: 1125 PGRVGLQGPKGMRGLEGTAGLP------GPPGPRGFQGMAG------------------- 1159 RG +G G P GPPGP G G+ G Sbjct: 80 ------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127 Query: 1160 --ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENT 1217 +G G GP G GP G PGP+G +G GEP Sbjct: 128 GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG------------------------- 162 Query: 1218 RPPMPILEQKLEPGTE----PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPG 1273 EPG P G PG K GE G+ G+ E RG PG G G PG Sbjct: 163 -----------EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE-RGPPGPQGARGFPG 210 Query: 1274 QQG 1276 G Sbjct: 211 TPG 213 Score = 73.2 bits (178), Expect = 2e-12 Identities = 45/116 (38%), Positives = 49/116 (42%), Gaps = 24/116 (20%) Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131 GP G +G G PG G G +GF G +G PG G GD G G G G +G PG VG Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1103 Query: 1132 G------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175 G P G RG G G GPP G G GPPG GP Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPP------------GNPGPPGPPGPPGP 1147 Score = 69.3 bits (168), Expect = 2e-11 Identities = 44/111 (39%), Positives = 53/111 (47%), Gaps = 6/111 (5%) Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 +S GP GP+GPPG G +G G G PGP GPPG +G G+ G G G+PG G PG Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143 Query: 1127 RVGLQGPKGMRGLEGTAGL-PGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176 G G+ + AGL P GP Q M + G R V T Sbjct: 1144 PPG----PGI-DMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDAT 1189 Score = 47.4 bits (111), Expect = 9e-05 Identities = 24/57 (42%), Positives = 27/57 (47%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG 1105 P+ G P S ++ PGP GP GP G G G G G PGP GPPG G Sbjct: 1090 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146 Score = 46.2 bits (108), Expect = 2e-04 Identities = 26/60 (43%), Positives = 27/60 (45%) Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108 PA G P S G PGP GPPG GR+G G G PG GPPG G G Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.134 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,988,410 Number of Sequences: 37866 Number of extensions: 3872368 Number of successful extensions: 62059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 281 Number of HSP's successfully gapped in prelim test: 589 Number of HSP's that attempted gapping in prelim test: 14284 Number of HSP's gapped (non-prelim): 8657 length of query: 1284 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1170 effective length of database: 13,930,794 effective search space: 16299028980 effective search space used: 16299028980 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.