Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 112734845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
         (1284 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]               2595   0.0  
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                459   e-128
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   427   e-119
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...   427   e-119
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         266   1e-70
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   208   3e-53
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]      183   8e-46
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        182   2e-45
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               169   1e-41
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]      159   2e-38
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]      159   2e-38
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]      155   2e-37
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]      155   2e-37
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]      152   3e-36
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]      152   3e-36
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    144   5e-34
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      144   5e-34
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     143   9e-34
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              143   9e-34
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  142   2e-33
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   142   2e-33
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   142   2e-33
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   142   2e-33
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   142   2e-33
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   141   4e-33
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   141   4e-33
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   141   4e-33
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      141   4e-33
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   141   5e-33
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   141   5e-33

>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score = 2595 bits (6727), Expect = 0.0
 Identities = 1284/1284 (100%), Positives = 1284/1284 (100%)

Query: 1    MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV 60
            MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV
Sbjct: 1    MSSGDPAHLGLCLWLWLGATLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQV 60

Query: 61   KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS 120
            KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS
Sbjct: 61   KPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSS 120

Query: 121  LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM 180
            LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM
Sbjct: 121  LDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADM 180

Query: 181  VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE 240
            VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE
Sbjct: 181  VFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKE 240

Query: 241  QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA 300
            QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA
Sbjct: 241  QVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAA 300

Query: 301  RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ 360
            RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ
Sbjct: 301  RVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQ 360

Query: 361  GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420
            GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR
Sbjct: 361  GGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420

Query: 421  EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP 480
            EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP
Sbjct: 421  EVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTP 480

Query: 481  RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR 540
            RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR
Sbjct: 481  RTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLR 540

Query: 541  GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG 600
            GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG
Sbjct: 541  GPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSG 600

Query: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
            QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG
Sbjct: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660

Query: 661  DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY 720
            DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY
Sbjct: 661  DAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAY 720

Query: 721  YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
            YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG
Sbjct: 721  YRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780

Query: 781  LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL 840
            LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL
Sbjct: 781  LGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSL 840

Query: 841  PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT 900
            PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT
Sbjct: 841  PGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHT 900

Query: 901  IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ 960
            IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ
Sbjct: 901  IVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQ 960

Query: 961  EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR 1020
            EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR
Sbjct: 961  EVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPR 1020

Query: 1021 SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP 1080
            SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP
Sbjct: 1021 SSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPP 1080

Query: 1081 GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE 1140
            GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE
Sbjct: 1081 GLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE 1140

Query: 1141 GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL 1200
            GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL
Sbjct: 1141 GTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL 1200

Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260
            VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR
Sbjct: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260

Query: 1261 GEPGAVGQMGSPGQQGASTQGLWE 1284
            GEPGAVGQMGSPGQQGASTQGLWE
Sbjct: 1261 GEPGAVGQMGSPGQQGASTQGLWE 1284


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score =  459 bits (1180), Expect = e-128
 Identities = 293/838 (34%), Positives = 453/838 (54%), Gaps = 63/838 (7%)

Query: 20  TLGREQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPK 79
           T+ + QV     LR  V+  D +Q+ W+   G   GY + V P +G    ++ L     K
Sbjct: 24  TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83

Query: 80  ATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPS 139
           A + GL P + YT+QI           A+ +F I+DL+                      
Sbjct: 84  AIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRK------------------- 124

Query: 140 HTGSPDPEQASEPQVAFTPSQDPRTPAGPQ---FRCLPPVPADMVFLVDGSWSIGHSHFQ 196
                DP    +P+V      +   P+ P+   F C  P  AD+V LVDGSWSIG  +F+
Sbjct: 125 -----DP----KPRVKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFR 175

Query: 197 QVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNT 256
            V+ FL +++  F++G +K ++GL QYSGD + EW LN+ STK++V+ AVR L YKGGNT
Sbjct: 176 LVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNT 235

Query: 257 FTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVK 316
            TGLAL ++   + +P AG R   +K+ IL+TDGKSQDD+   +R L++ GV +FA+GVK
Sbjct: 236 LTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVK 295

Query: 317 NADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDT 376
           NAD  EL+ +AS P    V++V +F  +  +   L+R +C R++    R+  A+A A+ T
Sbjct: 296 NADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVE-EQDREIKASAHAI-T 353

Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436
            P PT L+ S+VT+ S  ++WT AP +  KY +V+  +RGG P EVVV+G  +ST L NL
Sbjct: 354 GP-PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNL 412

Query: 437 ASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHY 496
            S TEY ++VF IY     EGLRG  TT  LP    L L  VT  ++ + W    GA+ Y
Sbjct: 413 MSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGY 472

Query: 497 LVRCSPASPKGEEEEREVQVG--RPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554
           L+  +P +     +E+E+++G    ++ L GL P  +Y V+V ++ G E S+    +  T
Sbjct: 473 LILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETT 532

Query: 555 PTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLG 614
             L+PPR+L  S+V  ++AR+ W+   R +   R+ Y +++G    + E     T+  L 
Sbjct: 533 LALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEV-DPITTFPLK 591

Query: 615 PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAW-VAAAPS 673
            L+  T YT+ +  +Y  G S  LTG  TT++ P+   L + E+  D+ ++ W   +A  
Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651

Query: 674 GVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLR 733
           G  ++++ W P+  GK  E+ +     + V+ GL   TEY+V++LA   DG+ S+ V+  
Sbjct: 652 G--LHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAV 709

Query: 734 YT--------PST----------VSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
            T        P+T          V ++   NL +  ET  SL+V W      V  + +TY
Sbjct: 710 GTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTY 769

Query: 776 APASGLGPEK----SVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             A G  PE+    +V VPG+++++ L  L   T+Y+V V+ IY  G   +VSA G+T
Sbjct: 770 MTAQG-DPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKT 826



 Score =  383 bits (984), Expect = e-106
 Identities = 212/526 (40%), Positives = 288/526 (54%), Gaps = 71/526 (13%)

Query: 823  VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881
            V  T    CP +  DG  L GF +M  F LVEK ++S+ GV+MEP  F   P + L KDA
Sbjct: 1209 VCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKDA 1268

Query: 882  QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941
             +++    ++P  LP ++TI FL R+LP+TP+E FALW++  ++  PL+GV+LD G K+L
Sbjct: 1269 LVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKTL 1328

Query: 942  TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001
            TYF+ D     Q  TF+  E+RKIF+GSFHK+H+ V  + V++ +DC++V E+ +    +
Sbjct: 1329 TYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASAN 1388

Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061
              + G   LG++ ++RGP  +SA FQLQM  IVCS +WA+ D+CCELP  RD E+CP   
Sbjct: 1389 ITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDLP 1448

Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP--------------------- 1100
             +CSCS       GP GPPG PG  G  G+QG PGP+GP                     
Sbjct: 1449 HSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQGP 1508

Query: 1101 -----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
                       PG KGEKGD GLPG QG PG  G PGR G  G +G+ G +G++G PGPP
Sbjct: 1509 SGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGPP 1568

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQA----- 1204
            GP G  G  G  G +G  GP G +GP G+PG KGERGE+G+ QS A +  +  Q      
Sbjct: 1569 GPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQLI 1628

Query: 1205 -SHVSKFDSF------------------HENTRPPMPILE-QKLEPGTEPL-------GS 1237
             SH++++ +                    E  RP  P    ++  PGT          G+
Sbjct: 1629 QSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGT 1688

Query: 1238 PGTRSKALVPGEWGRGGRHLEG-RGEPGAVG-----QMGSPGQQGA 1277
            PG R    + GE G  G   +G RG PG  G     + GSPG  G+
Sbjct: 1689 PGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGS 1734



 Score =  135 bits (341), Expect = 2e-31
 Identities = 77/208 (37%), Positives = 116/208 (55%), Gaps = 3/208 (1%)

Query: 158  PSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKV 216
            P+  P  P  P         AD+VF+VDGSWSIG  +F ++  FL S +    +IG D  
Sbjct: 1013 PTFPPTIP--PAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGT 1070

Query: 217  QVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGL 276
            QV + Q++ D +TE+ LN+  TKE +L A++ + YKGGNT TG A+ +V        +G 
Sbjct: 1071 QVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGT 1130

Query: 277  RPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVH 336
            R    KV++++TDG+SQDDV+  +R ++  G ++FA+GV +AD +EL  + S P    V 
Sbjct: 1131 RRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVF 1190

Query: 337  SVLDFLQLGALAGLLSRLICQRLQGGSP 364
             V DF     +   L   +C+      P
Sbjct: 1191 FVDDFDAFKKIEDELITFVCETASATCP 1218



 Score =  125 bits (315), Expect = 2e-28
 Identities = 123/483 (25%), Positives = 208/483 (43%), Gaps = 38/483 (7%)

Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA---SRGGTPREVVVEGPAASTEL 433
           LP  + L+L  VT +S+R+ W   P     YLI++        G  +E+ +       EL
Sbjct: 443 LPMASDLLLYDVTENSMRVKWDAVPGAS-GYLILYAPLTEGLAGDEKEMKIGETHTDIEL 501

Query: 434 HNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGA 493
             L   TEY V+V+ ++     + + G  TT  L PPR L ++ V   +  LTW P++  
Sbjct: 502 SGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQ 561

Query: 494 TH-YLVRCSPASPKGEEEEREVQVGRPEVL-LDGLEPGRDYEVSVQSLRGPEGSEARGIR 551
            + Y +  + A      E  EV+V       L GL P  +Y +++ S+     SE     
Sbjct: 562 INGYRIVYNNADGT---EINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGV 618

Query: 552 ARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSA 611
             T  +   ++L   +V+ D+ RV W        L ++ ++   GG + +        S 
Sbjct: 619 FTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSH 678

Query: 612 TLGPLSSSTTYTVRVTCLYPGGGSSTLTGRV-----------TTKKAPSPSQLSMTE--- 657
            +  L   T Y V +  +   G  S +   V            T   P+ S  S+ +   
Sbjct: 679 VIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGI 738

Query: 658 ---LPGD----AVQLAWVAAAPSGVLVYQITW-TPLGEGKAHEIS---VPGNLGTAVLPG 706
              + GD    ++++ W   + S V  +++T+ T  G+ +   I    VPG+    +L  
Sbjct: 739 RNLVVGDETTSSLRVKW-DISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKP 797

Query: 707 LGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG 766
           L   TEY VT+   Y DG   + VS+     T+  S P NL ++ E  + L+++W PP  
Sbjct: 798 LLPDTEYKVTVTPIYTDG---EGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSS 854

Query: 767 RVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSAT 826
            V  Y + Y P S  GP     V    + + + +L +   Y V + A  A+G S+A++  
Sbjct: 855 PVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGM 914

Query: 827 GQT 829
            +T
Sbjct: 915 VKT 917



 Score =  114 bits (284), Expect = 8e-25
 Identities = 73/199 (36%), Positives = 84/199 (42%), Gaps = 56/199 (28%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            RDG      +     SS  PGPPGP    G PG+PG  G+ G QG  GP G PG KGE+G
Sbjct: 1546 RDGSPGQRGLPGKDGSSGPPGPPGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERG 1605

Query: 1109 DHG-------------------------------------------LPGLQGHPGHQGIP 1125
            + G                                           + G  G PG  G P
Sbjct: 1606 ERGDLQSQAMVRSVARQVCEQLIQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSP 1665

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARG-----TSGERGPPGTVGPTG--- 1177
            G  G QGP G  G  G AG+PG PG RG  G+ G +G     T G RGPPG  GP+G   
Sbjct: 1666 GAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESR 1725

Query: 1178 --LPGPKGERGEKGEPQSL 1194
               PGP G  G +G P  L
Sbjct: 1726 PGSPGPPGSPGPRGPPGHL 1744



 Score =  100 bits (248), Expect = 1e-20
 Identities = 56/125 (44%), Positives = 65/125 (52%), Gaps = 12/125 (9%)

Query: 1058 PAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG 1117
            P+  S+       PG PG  G PG PG  G PG  GFPG  G PG  GE+G  G+ G +G
Sbjct: 1643 PSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKG 1702

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAG--LPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
            +PG       VG QGP+G  G  G +G   PG PGP    G  G RG  G  G PG  GP
Sbjct: 1703 NPG-------VGTQGPRGPPGPAGPSGESRPGSPGP---PGSPGPRGPPGHLGVPGPQGP 1752

Query: 1176 TGLPG 1180
            +G PG
Sbjct: 1753 SGQPG 1757



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 38/114 (33%), Positives = 43/114 (37%), Gaps = 34/114 (29%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL----------------- 1112
            +PG PG QGPPG PG  G  G  G PG RG  G+KGEKG+ G+                 
Sbjct: 1664 SPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGE 1723

Query: 1113 -----------------PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
                             PG  G PG QG  G+ G   P         A  P  P
Sbjct: 1724 SRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGVRAPHPDQP 1777



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 57/205 (27%), Positives = 91/205 (44%), Gaps = 14/205 (6%)

Query: 366  QGPAAAPALDTLPA--PTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWR-ASRGGTPRE 421
            +G + +    TLP+  P +L +S+   + +R++W P P  P+K Y IV++  S  G   E
Sbjct: 816  EGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDP-PSSPVKGYRIVYKPVSVPGPTLE 874

Query: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
              V     +  + NL S  +Y V +F     G  + L G+V T  L     L    V   
Sbjct: 875  TFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTN-LQAKHVEMT 933

Query: 482  TVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV----Q 537
            ++   WQ    AT Y V       + +++E  V  G       GL+P  +Y++SV    Q
Sbjct: 934  SLCAHWQVHRHATAYRVVIESLQDR-QKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQ 992

Query: 538  SLRGPEGS---EARGIRARTPTLAP 559
             + GP  S   + + +  R PT  P
Sbjct: 993  EIEGPSVSIMEKTQSLPTRPPTFPP 1017



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/95 (34%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802
           PP+ L  +  T  S  V+WT   G V  Y + Y P  G  P++ V V G  S   L +L 
Sbjct: 355 PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVV-VDGTVSSTVLKNLM 413

Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQTACPALRPD 837
           + T+Y++ V AIYA   SE +  T  T    +  D
Sbjct: 414 SLTEYQIAVFAIYAHTASEGLRGTETTLALPMASD 448


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
           [Homo sapiens]
          Length = 1899

 Score =  427 bits (1098), Expect = e-119
 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%)

Query: 172 CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231
           CL    AD+V LVDGSWSIG ++F+ V+ F++ ++  F+IGP +VQ+ L QYSGD +TEW
Sbjct: 28  CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 87

Query: 232 DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291
            LN+   K+ +L AV  L YKGGNT TG+AL  +  QN +  AG+RP A K+ +L+TDGK
Sbjct: 88  QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 147

Query: 292 SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351
           SQDDV   ++ LKD GV +FA+G+KNADE EL+++A+ P D   ++V DF  L  +   L
Sbjct: 148 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 207

Query: 352 SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411
           +  +C  ++G               L AP++LV+S+ T  S R+SWTP      +Y + +
Sbjct: 208 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 255

Query: 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471
               GG  +E  V     ST L +L   TEY+V+V+ + E    E L+G   T P+P   
Sbjct: 256 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 314

Query: 472 ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529
           +L +  V P T+H+ WQP  GAT Y++   P         +EV++G    ++ L  L P 
Sbjct: 315 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 374

Query: 530 RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589
            +Y V+VQ++     SE   +R  T  L  P+ L   DV+H    VFWE  P  VR   V
Sbjct: 375 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 434

Query: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649
            Y + E     + E   + TS +L  L S T YTV V+ ++  G S  +T + TT+  P+
Sbjct: 435 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 493

Query: 650 PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709
           P+ L +TE+  +  +  W   A S V +Y+ITW P G     E  + G+  T V   L  
Sbjct: 494 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 552

Query: 710 HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764
           +T Y+V+I A Y D + SD +  S R  P   +++P   P NL + + T +SL V W P 
Sbjct: 553 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 612

Query: 765 LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
            GRV  Y +TY P++G G E++ ++ G ++ V L  L+  T Y + VS++Y  G    ++
Sbjct: 613 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 672

Query: 825 ATGQT 829
             G+T
Sbjct: 673 GRGKT 677



 Score =  362 bits (930), Expect = e-99
 Identities = 199/494 (40%), Positives = 281/494 (56%), Gaps = 52/494 (10%)

Query: 823  VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881
            V  T  ++CP +  DG + PGF ++ A++L EK +AS++GV++E  +F     + + K+A
Sbjct: 1336 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 1395

Query: 882  QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941
             + +  +D++P  LPP +TI+ L RLLPETP + FA+WQ+T  D++P +GV+ D   K+L
Sbjct: 1396 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 1455

Query: 942  TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001
            ++F++D R  +Q  TFD +EV+ +F+GSFHKVH+ V    V++Y+DC ++ E+ + E G+
Sbjct: 1456 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 1515

Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061
                G+  LG+L K       SAAFQ+Q   IVCS  W   DRCC++P+ RD   CPAF 
Sbjct: 1516 ITTDGYEILGKLLKG---ERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 1572

Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            ++C+C+ ++ GPPGP GP G PG  G  GE+G  G  GPP   G +GD G PG QG PG 
Sbjct: 1573 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP---GPRGDIGPPGPQGPPGP 1629

Query: 1122 QG-----IPGRVGLQGPK------GMRGLEGTAGLPGPPGP------RGFQGMAGARGTS 1164
            QG     IPG  G QG K      G+ G  GT GLPGPPGP      RGF G  GA G  
Sbjct: 1630 QGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 1689

Query: 1165 GERGPPGTVGPTGL---------------PGPKGERGEKGEPQSLATLYQLVSQASHV-- 1207
            G  GPPG+ G  G+               PGP G +GEKG+   +A+   + + A  V  
Sbjct: 1690 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 1749

Query: 1208 ----SKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGE 1262
                 + + F++   + P      + +PG  P G PG    A   GE G GGR     G 
Sbjct: 1750 QLISGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGF 1803

Query: 1263 PGAVGQMGSPGQQG 1276
            PG  G  G PG++G
Sbjct: 1804 PGTPGMQGPPGERG 1817



 Score =  178 bits (452), Expect = 3e-44
 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%)

Query: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436
           +PAPT+L +++VTS   R +W         Y I W         E ++ G   +    NL
Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550

Query: 437 ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488
              T Y VS+  IY          G    L  L T AP   PR L +   T  ++ + W 
Sbjct: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 610

Query: 489 PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547
           P++G    Y +   P++ +G E+   +   +  V+L  L+P   Y ++V SL  P+G   
Sbjct: 611 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 669

Query: 548 RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606
           R   R +T  L   R+L   D S     V W+ A    R  ++ Y  + GG       PG
Sbjct: 670 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 729

Query: 607 NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           N   A L  L   T+YTV V  +Y    GG ++ TGR   +      Q+     P +++ 
Sbjct: 730 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 787

Query: 665 LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723
           + W   AP  VL Y++ ++P+ G   +  I VPGN     L  L   T Y V ++A Y D
Sbjct: 788 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 846

Query: 724 G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782
           G     P   R    T+ RS P NL +  ET +SL V+W    G V  Y + Y+P  G  
Sbjct: 847 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 902

Query: 783 PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            ++  +VPG R++V L  LQ  T Y++ V A+Y  G    ++  G+T
Sbjct: 903 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 949



 Score =  145 bits (367), Expect = 2e-34
 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%)

Query: 40   DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99
            D   +KW     +   Y +++ P  G   QE+ +          GLSP   Y + +F   
Sbjct: 1054 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 1109

Query: 100  GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159
                                      Q P   G       HT     E  +EP    TP 
Sbjct: 1110 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 1141

Query: 160  QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218
              P  P  P         AD+VFL D SWSIG  +F +V  F+ + +  F EI P  +QV
Sbjct: 1142 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 1199

Query: 219  GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278
               QYS + ++E+ LN+ + K   L A++ +RY+GGNT TG ALT +  + L   +G+R 
Sbjct: 1200 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 1259

Query: 279  EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338
               KV+++VTDG+SQD+V  AA V++  G +VF VGV + D  EL  +AS P +  V  V
Sbjct: 1260 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 1319

Query: 339  LDFLQLGALAGLLSRLICQRLQGGSP 364
             DF     +   L   +C+      P
Sbjct: 1320 DDFESFEKIEDNLITFVCETATSSCP 1345



 Score =  143 bits (360), Expect = 1e-33
 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%)

Query: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438
            P +L +   TS+S+ + W PA     KY I ++ S G G  +   + G   S  L  L  
Sbjct: 592  PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 651

Query: 439  RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497
             T Y ++V  +Y  G G  + G   T PL   R L +   +  T+++ W  + G    Y 
Sbjct: 652  DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 711

Query: 498  VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557
            +  +PA+  G EE   +       +L  L+P   Y V+V  +             RT   
Sbjct: 712  LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 770

Query: 558  APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616
               R++   + + ++  V W+ AP PV   RV Y   +G    ++   PGN     L  L
Sbjct: 771  GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 830

Query: 617  SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676
               T Y+V +  LY  G  +    +  T     P  L +     +++ +AW   A   V 
Sbjct: 831  IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 889

Query: 677  VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735
             Y+I ++P +G+      +VPG     +L  L   T Y +T++A Y DG   D   L   
Sbjct: 890  QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 946

Query: 736  PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795
              TV   PP N+ ++ E     +VSW P    VL Y + Y P     P +  +  G  + 
Sbjct: 947  GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 1004

Query: 796  VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             TL +L  +T Y V V A Y +G S  ++  G T
Sbjct: 1005 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 1038



 Score =  113 bits (283), Expect = 1e-24
 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%)

Query: 389  TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447
            T +S+ + W PAP   L+Y +V+    G  P E +VV G      L  L   T Y V++ 
Sbjct: 782  TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 841

Query: 448  PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506
             +Y  G G        T P   PR L +   T  ++ + W  + G    Y +  SP    
Sbjct: 842  ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 901

Query: 507  GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565
              +E   V   R  V+L  L+P   Y+++V ++    +G    G   RT  L PP+++  
Sbjct: 902  PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 960

Query: 566  SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625
            SD  +   RV W+ +P PV   ++ Y    G +       G  TS TL  L+ STTY V 
Sbjct: 961  SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 1019

Query: 626  VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685
            V   Y  G S  LT + TT    + + L   ++  D   + W  +       Y++  +P 
Sbjct: 1020 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 1076

Query: 686  GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717
               +  EI+V G+  +    GL   T+Y VT+
Sbjct: 1077 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 1108



 Score =  106 bits (264), Expect = 2e-22
 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            S   PGPPGP GPP      G+ G +G PGP G PG        G PG+QG PG +G+PG
Sbjct: 1773 SRNQPGPPGPPGPP------GSAGARGEPGPGGRPGFP------GTPGMQGPPGERGLPG 1820

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G +G     G  G  GLPGPPGP+G +   G  G++G RGPP   GP G PG  G RG
Sbjct: 1821 EKGERG----TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 1872

Query: 1187 EKGEP 1191
              G P
Sbjct: 1873 PPGPP 1877



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%)

Query: 363  SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420
            SP QG        TLP   P +L +   T++S+ ++W  A     +Y I++  + G    
Sbjct: 852  SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 904

Query: 421  E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479
            E   V G   +  L  L   T Y ++V  +YE G G  L G   T  L PP+ + ++   
Sbjct: 905  EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 964

Query: 480  PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538
                 ++W PS      L       P G  E  E  VG      L  L P   Y+V+V +
Sbjct: 965  YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 1022

Query: 539  LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598
             +   G         T        L    +  D   V W    R     R+    ++G  
Sbjct: 1023 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 1080

Query: 599  SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652
              +    G+ TS     LS  T Y V V    P   G   ++    T K   +P++
Sbjct: 1081 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 1136



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%)

Query: 42  LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101
           L ++W  +EG+   Y +   P AG  E+ V +   T  A +  L P   YT+ +  +   
Sbjct: 696 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 755

Query: 102 GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156
           G           +  ++S   R+  R L        PTP+       P P    + +V +
Sbjct: 756 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 804

Query: 157 TPSQDPR 163
           +P    R
Sbjct: 805 SPVDGTR 811


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score =  427 bits (1098), Expect = e-119
 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%)

Query: 172  CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231
            CL    AD+V LVDGSWSIG ++F+ V+ F++ ++  F+IGP +VQ+ L QYSGD +TEW
Sbjct: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 1251

Query: 232  DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291
             LN+   K+ +L AV  L YKGGNT TG+AL  +  QN +  AG+RP A K+ +L+TDGK
Sbjct: 1252 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 1311

Query: 292  SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351
            SQDDV   ++ LKD GV +FA+G+KNADE EL+++A+ P D   ++V DF  L  +   L
Sbjct: 1312 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 1371

Query: 352  SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411
            +  +C  ++G               L AP++LV+S+ T  S R+SWTP      +Y + +
Sbjct: 1372 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 1419

Query: 412  RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471
                GG  +E  V     ST L +L   TEY+V+V+ + E    E L+G   T P+P   
Sbjct: 1420 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 1478

Query: 472  ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529
            +L +  V P T+H+ WQP  GAT Y++   P         +EV++G    ++ L  L P 
Sbjct: 1479 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 1538

Query: 530  RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589
             +Y V+VQ++     SE   +R  T  L  P+ L   DV+H    VFWE  P  VR   V
Sbjct: 1539 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 1598

Query: 590  TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649
             Y + E     + E   + TS +L  L S T YTV V+ ++  G S  +T + TT+  P+
Sbjct: 1599 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 1657

Query: 650  PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709
            P+ L +TE+  +  +  W   A S V +Y+ITW P G     E  + G+  T V   L  
Sbjct: 1658 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 1716

Query: 710  HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764
            +T Y+V+I A Y D + SD +  S R  P   +++P   P NL + + T +SL V W P 
Sbjct: 1717 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 1776

Query: 765  LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
             GRV  Y +TY P++G G E++ ++ G ++ V L  L+  T Y + VS++Y  G    ++
Sbjct: 1777 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 1836

Query: 825  ATGQT 829
              G+T
Sbjct: 1837 GRGKT 1841



 Score =  362 bits (930), Expect = e-99
 Identities = 199/494 (40%), Positives = 281/494 (56%), Gaps = 52/494 (10%)

Query: 823  VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881
            V  T  ++CP +  DG + PGF ++ A++L EK +AS++GV++E  +F     + + K+A
Sbjct: 2500 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 2559

Query: 882  QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941
             + +  +D++P  LPP +TI+ L RLLPETP + FA+WQ+T  D++P +GV+ D   K+L
Sbjct: 2560 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 2619

Query: 942  TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001
            ++F++D R  +Q  TFD +EV+ +F+GSFHKVH+ V    V++Y+DC ++ E+ + E G+
Sbjct: 2620 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 2679

Query: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061
                G+  LG+L K       SAAFQ+Q   IVCS  W   DRCC++P+ RD   CPAF 
Sbjct: 2680 ITTDGYEILGKLLKG---ERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 2736

Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            ++C+C+ ++ GPPGP GP G PG  G  GE+G  G  GPP   G +GD G PG QG PG 
Sbjct: 2737 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP---GPRGDIGPPGPQGPPGP 2793

Query: 1122 QG-----IPGRVGLQGPK------GMRGLEGTAGLPGPPGP------RGFQGMAGARGTS 1164
            QG     IPG  G QG K      G+ G  GT GLPGPPGP      RGF G  GA G  
Sbjct: 2794 QGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853

Query: 1165 GERGPPGTVGPTGL---------------PGPKGERGEKGEPQSLATLYQLVSQASHV-- 1207
            G  GPPG+ G  G+               PGP G +GEKG+   +A+   + + A  V  
Sbjct: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913

Query: 1208 ----SKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGE 1262
                 + + F++   + P      + +PG  P G PG    A   GE G GGR     G 
Sbjct: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGF 2967

Query: 1263 PGAVGQMGSPGQQG 1276
            PG  G  G PG++G
Sbjct: 2968 PGTPGMQGPPGERG 2981



 Score =  302 bits (774), Expect = 1e-81
 Identities = 224/695 (32%), Positives = 336/695 (48%), Gaps = 24/695 (3%)

Query: 176  VPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNS 235
            + AD+VFLVDGS+SIG ++F +V+ FL  ++  FEI P++VQ+ L QYS D  TE+ L  
Sbjct: 437  IKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKK 496

Query: 236  LSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDD 295
             +  E ++ A+    Y+GG+T TG A+T+V  +   P+ G R    KV+IL+TDGKS D 
Sbjct: 497  FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556

Query: 296  VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355
                A  L++  V +FAVGVK+A  +EL  +ASPP +  V +V DF     ++  L++ I
Sbjct: 557  FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASR 415
            C R++     Q  AA      +P P  L  S+VTS   + +W+PA  +   Y I ++ + 
Sbjct: 617  CLRIE-----QELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAA 670

Query: 416  GGTPREVVVEGPAASTE--LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLP-PPRA 472
            G    EV V  PA+ST   L +L   T YLV+V   YE G    L G  TT  +   PR 
Sbjct: 671  GDD--EVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728

Query: 473  LTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRD 531
            L +   T  +  +TW  + G    Y +   P +  GE  E      +    L+ L P   
Sbjct: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTK 787

Query: 532  YEVSV--QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589
            YEVSV  +   GP G+   G  A       PR L  SD +    ++ W GAP  V+   V
Sbjct: 788  YEVSVIPEYFSGP-GTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLV 846

Query: 590  TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT-KKAP 648
            TY    GG + +    G+ T+  L  L   T Y + VT LY  G    L G  TT ++  
Sbjct: 847  TYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERG 906

Query: 649  SPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGL 707
            SP  L   ++   ++   W  +AP  V  Y+++W  L  +    E ++P +    ++  L
Sbjct: 907  SPQDLVTKDITDTSIGAYW-TSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENL 965

Query: 708  GRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGR 767
               T+Y +++ A Y  G   +P  L    +T        L +  ET ++++V+W P  G+
Sbjct: 966  QPETKYRISVFATYSSG-EGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022

Query: 768  VLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATG 827
            V++Y + Y P  G G +    VP   +   L  LQ  T Y + V  IY  G  +    +G
Sbjct: 1023 VVNYRVVYRP-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081

Query: 828  QTACPALRPDGSLPGFDLMVAFSLV-EKAYASIRG 861
             TA     P         M +F +  E A   ++G
Sbjct: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKG 1116



 Score =  199 bits (506), Expect = 1e-50
 Identities = 125/457 (27%), Positives = 227/457 (49%), Gaps = 58/457 (12%)

Query: 17  LGATLGREQVQAS----GLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVI 72
           LGA L    ++A       L   ++ E+ + M W +     +GY + V P      +E  
Sbjct: 12  LGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFT 71

Query: 73  LTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSG 132
           L+  T +  +  L P   Y + I                   D    S+    Q  + +G
Sbjct: 72  LSASTTETLLSELVPETEYVVTITSY----------------DEVEESVPVIGQLTIQTG 115

Query: 133 AP-EPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIG 191
           +  +P     G  + +                       +C      D+VFLVDGSWS+G
Sbjct: 116 SSTKPVEKKPGKTEIQ-----------------------KCSVSAWTDLVFLVDGSWSVG 152

Query: 192 HSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRY 251
            ++F+ + DF+A++++ F+IG +K +VG+ QYS D +TE++LN    ++++LAA++++ Y
Sbjct: 153 RNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPY 212

Query: 252 KGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVF 311
           KGGNT TG A+ +++      +AG R    KV I++TDGKSQD+V   AR L+++GV VF
Sbjct: 213 KGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVF 272

Query: 312 AVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAA 371
           ++G+K AD  EL+ +AS P   +++ V +     A+  + + +I Q   G   + G   +
Sbjct: 273 SLGIKAADAKELKQIASTP---SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVS 329

Query: 372 PALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAAST 431
              + +  P++L+  +V+S  ++L+W P+P     Y ++      G+ +  +  GP  +T
Sbjct: 330 -GEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTT 388

Query: 432 -ELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPL 467
             + +L++ TEY +SV           ++G+ ++ P+
Sbjct: 389 LSVRDLSADTEYQISV---------SAMKGMTSSEPI 416



 Score =  178 bits (452), Expect = 3e-44
 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%)

Query: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436
            +PAPT+L +++VTS   R +W         Y I W         E ++ G   +    NL
Sbjct: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 1714

Query: 437  ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488
               T Y VS+  IY          G    L  L T AP   PR L +   T  ++ + W 
Sbjct: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774

Query: 489  PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547
            P++G    Y +   P++ +G E+   +   +  V+L  L+P   Y ++V SL  P+G   
Sbjct: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 1833

Query: 548  RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606
            R   R +T  L   R+L   D S     V W+ A    R  ++ Y  + GG       PG
Sbjct: 1834 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 1893

Query: 607  NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
            N   A L  L   T+YTV V  +Y    GG ++ TGR   +      Q+     P +++ 
Sbjct: 1894 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 1951

Query: 665  LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723
            + W   AP  VL Y++ ++P+ G   +  I VPGN     L  L   T Y V ++A Y D
Sbjct: 1952 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 2010

Query: 724  G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782
            G     P   R    T+ RS P NL +  ET +SL V+W    G V  Y + Y+P  G  
Sbjct: 2011 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066

Query: 783  PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             ++  +VPG R++V L  LQ  T Y++ V A+Y  G    ++  G+T
Sbjct: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 2113



 Score =  177 bits (448), Expect = 8e-44
 Identities = 136/448 (30%), Positives = 205/448 (45%), Gaps = 12/448 (2%)

Query: 379  APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLAS 438
            AP +L ++  T+ S +++WT AP   L+Y I++R   GG  REV          L NL  
Sbjct: 725  APRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIP 784

Query: 439  RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPP-PRALTLAAVTPRTVHLTWQPSAGAT-HY 496
             T+Y VSV P Y  G G  L G   T  +   PR L ++  T  T+ L+W  + G    Y
Sbjct: 785  DTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQY 844

Query: 497  LVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR-GIRARTP 555
            LV  +P +  GE +E  V+      +L GL+ G  Y +SV +L      +A  G      
Sbjct: 845  LVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLE 903

Query: 556  TLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSS-EGGHSGQTEAPGNATSATLG 614
                P+ L   D++  +   +W  AP  VR  RV++ S  +   +G+   P +A    + 
Sbjct: 904  ERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIE 963

Query: 615  PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSG 674
             L   T Y + V   Y  G    LTG  TT+ +     L + E   + +++ W   AP  
Sbjct: 964  NLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK 1022

Query: 675  VLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRY 734
            V+ Y++ + P G GK     VP  + + VL  L   T YD+T+L  Y+ G       LR 
Sbjct: 1023 VVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK----LRQ 1078

Query: 735  -TPSTVSR-SPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGA 792
             + +T SR   P NL  +  T  S +V+W P  G V  Y +T+ P         + V   
Sbjct: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPY 1138

Query: 793  RSHVTLPDLQAATKYRVLVSAIYAAGRS 820
             + V L +L+A T Y+V V  ++  G S
Sbjct: 1139 DNTVVLEELRAGTTYKVNVFGMFDGGES 1166



 Score =  145 bits (367), Expect = 2e-34
 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%)

Query: 40   DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99
            D   +KW     +   Y +++ P  G   QE+ +          GLSP   Y + +F   
Sbjct: 2218 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 2273

Query: 100  GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159
                                      Q P   G       HT     E  +EP    TP 
Sbjct: 2274 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 2305

Query: 160  QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218
              P  P  P         AD+VFL D SWSIG  +F +V  F+ + +  F EI P  +QV
Sbjct: 2306 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 2363

Query: 219  GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278
               QYS + ++E+ LN+ + K   L A++ +RY+GGNT TG ALT +  + L   +G+R 
Sbjct: 2364 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 2423

Query: 279  EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338
               KV+++VTDG+SQD+V  AA V++  G +VF VGV + D  EL  +AS P +  V  V
Sbjct: 2424 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 2483

Query: 339  LDFLQLGALAGLLSRLICQRLQGGSP 364
             DF     +   L   +C+      P
Sbjct: 2484 DDFESFEKIEDNLITFVCETATSSCP 2509



 Score =  143 bits (360), Expect = 1e-33
 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%)

Query: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438
            P +L +   TS+S+ + W PA     KY I ++ S G G  +   + G   S  L  L  
Sbjct: 1756 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 1815

Query: 439  RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497
             T Y ++V  +Y  G G  + G   T PL   R L +   +  T+++ W  + G    Y 
Sbjct: 1816 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 1875

Query: 498  VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557
            +  +PA+  G EE   +       +L  L+P   Y V+V  +             RT   
Sbjct: 1876 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 1934

Query: 558  APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616
               R++   + + ++  V W+ AP PV   RV Y   +G    ++   PGN     L  L
Sbjct: 1935 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 1994

Query: 617  SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676
               T Y+V +  LY  G  +    +  T     P  L +     +++ +AW   A   V 
Sbjct: 1995 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 2053

Query: 677  VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735
             Y+I ++P +G+      +VPG     +L  L   T Y +T++A Y DG   D   L   
Sbjct: 2054 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 2110

Query: 736  PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795
              TV   PP N+ ++ E     +VSW P    VL Y + Y P     P +  +  G  + 
Sbjct: 2111 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 2168

Query: 796  VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             TL +L  +T Y V V A Y +G S  ++  G T
Sbjct: 2169 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202



 Score =  113 bits (283), Expect = 1e-24
 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%)

Query: 389  TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447
            T +S+ + W PAP   L+Y +V+    G  P E +VV G      L  L   T Y V++ 
Sbjct: 1946 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 2005

Query: 448  PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506
             +Y  G G        T P   PR L +   T  ++ + W  + G    Y +  SP    
Sbjct: 2006 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 2065

Query: 507  GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565
              +E   V   R  V+L  L+P   Y+++V ++    +G    G   RT  L PP+++  
Sbjct: 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 2124

Query: 566  SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625
            SD  +   RV W+ +P PV   ++ Y    G +       G  TS TL  L+ STTY V 
Sbjct: 2125 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 2183

Query: 626  VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685
            V   Y  G S  LT + TT    + + L   ++  D   + W  +       Y++  +P 
Sbjct: 2184 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 2240

Query: 686  GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717
               +  EI+V G+  +    GL   T+Y VT+
Sbjct: 2241 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 2272



 Score =  106 bits (264), Expect = 2e-22
 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            S   PGPPGP GPP      G+ G +G PGP G PG        G PG+QG PG +G+PG
Sbjct: 2937 SRNQPGPPGPPGPP------GSAGARGEPGPGGRPGFP------GTPGMQGPPGERGLPG 2984

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G +G     G  G  GLPGPPGP+G +   G  G++G RGPP   GP G PG  G RG
Sbjct: 2985 EKGERG----TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 3036

Query: 1187 EKGEP 1191
              G P
Sbjct: 3037 PPGPP 3041



 Score =  103 bits (256), Expect = 1e-21
 Identities = 80/275 (29%), Positives = 124/275 (45%), Gaps = 5/275 (1%)

Query: 374  LDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR-EVVVEGPAASTE 432
            L+   +P  LV   +T +SI   WT AP     Y + W++        E  +   A  T 
Sbjct: 902  LEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM 961

Query: 433  LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG 492
            + NL   T+Y +SVF  Y  G GE L G  TT      + L +   T  T+ +TW+P+ G
Sbjct: 962  IENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPG 1021

Query: 493  -ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGI 550
               +Y V   P   +G++   +V       +L  L+P   Y+++V  + +  EG   +G 
Sbjct: 1022 KVVNYRVVYRPHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080

Query: 551  RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTY-VSSEGGHSGQTEAPGNAT 609
                     PR+L  SD +  + RV WE AP  V+  +VT+  + +    G+        
Sbjct: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140

Query: 610  SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT 644
            +  L  L + TTY V V  ++ GG SS L G+  T
Sbjct: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMT 1175



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%)

Query: 363  SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420
            SP QG        TLP   P +L +   T++S+ ++W  A     +Y I++  + G    
Sbjct: 2016 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 2068

Query: 421  E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479
            E   V G   +  L  L   T Y ++V  +YE G G  L G   T  L PP+ + ++   
Sbjct: 2069 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 2128

Query: 480  PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538
                 ++W PS      L       P G  E  E  VG      L  L P   Y+V+V +
Sbjct: 2129 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 2186

Query: 539  LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598
             +   G         T        L    +  D   V W    R     R+    ++G  
Sbjct: 2187 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 2244

Query: 599  SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652
              +    G+ TS     LS  T Y V V    P   G   ++    T K   +P++
Sbjct: 2245 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 2300



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 24/87 (27%), Positives = 44/87 (50%)

Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802
           PPSNL     +   ++++W P    V  Y +   P +    + ++SV    + +++ DL 
Sbjct: 336 PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLS 395

Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQT 829
           A T+Y++ VSA+     SE +S   +T
Sbjct: 396 ADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 634 GSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEI 693
           G++ L   +  +  P PS L+   +  + V ++W A     ++ Y+IT  P  +G   E 
Sbjct: 13  GAALLLSSIEAEVDP-PSDLNFKIIDENTVHMSW-AKPVDPIVGYRITVDPTTDGPTKEF 70

Query: 694 SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPP 744
           ++  +    +L  L   TEY VTI + Y +   S PV  + T  T S + P
Sbjct: 71  TLSASTTETLLSELVPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKP 120



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 453 GVGEGLRGLVTTAPL-PPPRALTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEE 510
           GV E L  LV+   +  PP  L    V+ + V L W PS    T Y V  +P +    + 
Sbjct: 319 GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQH 378

Query: 511 EREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554
              V      + +  L    +Y++SV +++G   SE   I  +T
Sbjct: 379 ALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 21/71 (29%), Positives = 31/71 (43%)

Query: 32  LRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGY 91
           LR++      +++ W  + G    YLV   P+AG   QEV +   T    + GL     Y
Sbjct: 820 LRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQY 879

Query: 92  TLQIFELTGSG 102
            L +  L  SG
Sbjct: 880 ALSVTALYASG 890



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802
           PPS+L       +++ +SW  P+  ++ Y +T  P +  GP K  ++  + +   L +L 
Sbjct: 27  PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD-GPTKEFTLSASTTETLLSELV 85

Query: 803 AATKYRVLVSAIYAAGRSEAVSATGQ 828
             T+Y V +++       E+V   GQ
Sbjct: 86  PETEYVVTITSYDEV--EESVPVIGQ 109



 Score = 34.3 bits (77), Expect = 0.79
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 40  DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFE-- 97
           D  ++ W ++ G  L Y +  +P+AG   +EV       + T+  L P   Y + +    
Sbjct: 737 DSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796

Query: 98  LTGSGRFLL--ARREFV---IEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEP 152
            +G G  L   A  E V     DL+ S    S+ +   SGAP     +  +  P    E 
Sbjct: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET 856

Query: 153 Q 153
           Q
Sbjct: 857 Q 857



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 465 APLPPPRALTLAAVTPRTVHLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLL 523
           A + PP  L    +   TVH++W +P      Y +   P +  G  +E  +     E LL
Sbjct: 23  AEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLL 81

Query: 524 DGLEPGRDYEVSVQS 538
             L P  +Y V++ S
Sbjct: 82  SELVPETEYVVTITS 96



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%)

Query: 42   LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101
            L ++W  +EG+   Y +   P AG  E+ V +   T  A +  L P   YT+ +  +   
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 1919

Query: 102  GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156
            G           +  ++S   R+  R L        PTP+       P P    + +V +
Sbjct: 1920 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 1968

Query: 157  TPSQDPR 163
            +P    R
Sbjct: 1969 SPVDGTR 1975



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 27/126 (21%), Positives = 48/126 (38%), Gaps = 3/126 (2%)

Query: 559 PPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSS 618
           PP  L F  +  +   + W     P+   R+T   +  G + +     + T   L  L  
Sbjct: 27  PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVP 86

Query: 619 STTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDA-VQLAWVAAAPSGVLV 677
            T Y V +T       S  + G++T +   S   +   + PG   +Q   V+A    V +
Sbjct: 87  ETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVE--KKPGKTEIQKCSVSAWTDLVFL 144

Query: 678 YQITWT 683
              +W+
Sbjct: 145 VDGSWS 150


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  266 bits (679), Expect = 1e-70
 Identities = 229/687 (33%), Positives = 325/687 (47%), Gaps = 45/687 (6%)

Query: 159 SQDPRTPAGPQFR--CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFE--IGPD 214
           ++ PR  A  + R  C     AD+VFL+DGS SIG S+F++V+ FL  ++ PF       
Sbjct: 16  AEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQ 75

Query: 215 KVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAA 274
            V+    QYS D +TE+ L++L +   V+ A+R L YKGGNT TG A+ HV      P  
Sbjct: 76  GVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL 135

Query: 275 GLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDIT 334
             RP   KV IL+TDGKSQD V TAA+ LK  GV +FAVG+KNAD  EL+ +AS P    
Sbjct: 136 A-RPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDF 194

Query: 335 VHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIR 394
              V DF  L  L  L+SR +C    G      P   P  D+  AP  LVLS+ +S S+R
Sbjct: 195 FFFVNDFSILRTLLPLVSRRVCTTAGG-----VPVTRPPDDSTSAPRDLVLSEPSSQSLR 249

Query: 395 LSWTPAPRHPLKYLIVWRASRG-GTP-----REVVVEGPAASTELHNLASRTEYLVSVFP 448
           + WT A      Y + +    G G P     +EV V     S  L  L   TEY V+V  
Sbjct: 250 VQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIA 309

Query: 449 IYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGE 508
           +Y   +GE + G   T  L  P  LT+   T  ++ + W+   GAT Y V     S  G 
Sbjct: 310 LYANSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGATGYRVTWRVLS-GGP 367

Query: 509 EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP----PRHLG 564
            +++E+  G+  VLL  LEPG DYEV+V +L G     A  + ART         P  LG
Sbjct: 368 TQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVILG 427

Query: 565 FSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEAPGNATSATLGPLSSSTTYT 623
            + +      + W   P   R  R+ +    G    Q    P + T   L  L   T Y 
Sbjct: 428 PTSI-----LLSWNLVPE-ARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYR 481

Query: 624 VRVTCLYPGGGSSTLTGRVTT--KKAPSP-SQLSMTELPGDAVQLAWVAAAPSGVLVYQI 680
           + +  L  G   +T    V T  +   SP + L  TELPG  V+++W  +   G   Y+I
Sbjct: 482 LTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW--SPVPGATQYRI 539

Query: 681 TWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYY--RDGARSDPVSLRYTPST 738
                 +G    + +PG+     L  +     Y V + A    R+G+ S  +++R  P T
Sbjct: 540 I-VRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSAS-VLTVRREPET 597

Query: 739 VSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTL 798
               P   + ++  T   ++V+W P  G         + ++G GPE S ++P   +   +
Sbjct: 598 PLAVPGLRVVVSDAT--RVRVAWGPVPGA---SGFRISWSTGSGPESSQTLPPDSTATDI 652

Query: 799 PDLQAATKYRVLVSAIYAAGRSEAVSA 825
             LQ  T Y+V VS +   GR E  +A
Sbjct: 653 TGLQPGTTYQVAVSVL--RGREEGPAA 677



 Score =  144 bits (362), Expect = 7e-34
 Identities = 140/512 (27%), Positives = 218/512 (42%), Gaps = 28/512 (5%)

Query: 330 PRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVT 389
           P D+T +  LD LQ G    L    + +  +  +P       P L   P  T L  +++ 
Sbjct: 463 PSDVTRYQ-LDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPV-TDLQATELP 520

Query: 390 SSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPI 449
              +R+SW+P P    +Y I+ R+++G   R +V+ G   + +L ++ +   Y V V   
Sbjct: 521 GQRVRVSWSPVPG-ATQYRIIVRSTQG-VERTLVLPGSQTAFDLDDVQAGLSYTVRVSA- 577

Query: 450 YEGGVGEGLRGLVTT-----APLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPAS 504
              G  EG   ++T       PL  P    + +   R V + W P  GA+ + +  S  S
Sbjct: 578 -RVGPREGSASVLTVRREPETPLAVPGLRVVVSDATR-VRVAWGPVPGASGFRISWSTGS 635

Query: 505 PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLG 564
             G E  + +        + GL+PG  Y+V+V  LRG E   A  I ART  L P R + 
Sbjct: 636 --GPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVH 693

Query: 565 FSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTV 624
            +  S  +  + W   P      RV++ S+ G    Q    G AT A L  L   T YTV
Sbjct: 694 VTQASSSSVTITWTRVPGATG-YRVSWHSAHGPEKSQL-VSGEATVAELDGLEPDTEYTV 751

Query: 625 RVTCLYPG--GGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITW 682
            V     G  G  +++  R   +     S+L +     D +++ WV    +G   Y++ W
Sbjct: 752 HVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGV--TGATAYRLAW 809

Query: 683 TPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRS 742
                G      +PGN  +A + GL     Y V + A   D     PVS+  T  T   +
Sbjct: 810 GRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGD-REGTPVSIVVT--TPPEA 866

Query: 743 PPS--NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPD 800
           PP+   L +      SL++ W  P+ R   + L + P    G E+S  +    S   L  
Sbjct: 867 PPALGTLHVVQRGEHSLRLRW-EPVPRAQGFLLHWQPEG--GQEQSRVLGPELSSYHLDG 923

Query: 801 LQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832
           L+ AT+YRV +S +  AG   +   T +T  P
Sbjct: 924 LEPATQYRVRLSVLGPAGEGPSAEVTARTESP 955



 Score =  144 bits (362), Expect = 7e-34
 Identities = 102/276 (36%), Positives = 131/276 (47%), Gaps = 48/276 (17%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL------PGRNGTP---GEQGFPGPRG 1099
            PA   G+  P  +   S     PG  GP GP G       PGR+G P   GEQG PGP G
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGIP---------------GRVGLQGPKGMRGL----- 1139
            PPG+ G+ G+ G PGL G  G  G P               GR G  GPKG RG      
Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 1140 -EGTAGLPGPPGP--RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLAT 1196
             +G  GLPGP GP  +GF G+ G  G  G+RG  G+ G  GLPG +G RGE G   ++  
Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDR 1944

Query: 1197 LYQLVS-QASHVSKF-DSFHENTRPPMPILEQKL----------EPGTE-PLGSPGTR-- 1241
            L +    +AS + +  +++ E++   +P+ E++            PG E P+G PG R  
Sbjct: 1945 LLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGL 2004

Query: 1242 -SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                  PG  G  G  L  RG PG  G  G PG+ G
Sbjct: 2005 KGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG 2040



 Score =  134 bits (337), Expect = 6e-31
 Identities = 97/258 (37%), Positives = 116/258 (44%), Gaps = 52/258 (20%)

Query: 1070 TPGPPGP-----------------QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL 1112
            TPGPPGP                 QGPPGL G  G PG  G  GP+G  GV G KGD G 
Sbjct: 2083 TPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142

Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---------------PGPRGFQGM 1157
            PG +G  G+ G+PG  G+ GP+G  GL+G  G PGP                GP G QG 
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202

Query: 1158 AGARGTSGERGPP--GTVGPTGL------PGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            +G +G  GE GPP  G  GPTG       PGP G  G +G P     + +     +    
Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262

Query: 1210 FDSFHENTR-----PPMPILEQKLEPGTEPLGSPGTRSKALV--PGEWGR----GGRHLE 1258
              S  +  R     P  P L   + P  EP G  G   +A+V  PG  G     GG   +
Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEP-GPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321

Query: 1259 GRGEPGAVGQMGSPGQQG 1276
              GEPGA G  G PG +G
Sbjct: 2322 LVGEPGAKGDRGLPGPRG 2339



 Score =  132 bits (331), Expect = 3e-30
 Identities = 94/235 (40%), Positives = 107/235 (45%), Gaps = 24/235 (10%)

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
            E CP +          PG  G +G  G PG  G PG  G PGP+GPPG    KG+ G PG
Sbjct: 1245 EPCPVYCP--KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPG 1302

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV- 1173
              G PG    PGR G  G  G  GL+G+   PG PGPRG  G  G RG  GE G PG V 
Sbjct: 1303 ADGRPGS---PGRAGNPGTPGAPGLKGS---PGLPGPRGDPGERGPRGPKGEPGAPGQVI 1356

Query: 1174 ---GPTGLPGPKGERGEKGEPQSLATLYQLVSQA-----SHVSKFDSFHENTRPPMPILE 1225
               GP GLPG KG+ G  G P     L     +          K D      R P    E
Sbjct: 1357 GGEGP-GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE 1415

Query: 1226 QKLEPGTEPL----GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              + PG   L    GSPG +     PG+ G  G   +  G PG  GQ GSPG+QG
Sbjct: 1416 GGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED--GAPGLPGQPGSPGEQG 1468



 Score =  130 bits (327), Expect = 8e-30
 Identities = 93/218 (42%), Positives = 105/218 (48%), Gaps = 27/218 (12%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVK---GEKGDHGLPGLQGHPGHQGIP 1125
            GP GP+G PGLPG  G  G +GF   PGP+G PGV+   GEKGD G PGL G  G  G P
Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------GTSGERGPPGTVGPTGLP 1179
            G  G  GP G  G  G  G  G PG RG QG+ G        G  GE G PG  G  G P
Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847

Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE-PLGSP 1238
            G  GE G KGE           S AS     D   +  R    IL  +  PG   P+G P
Sbjct: 1848 GDPGEDGRKGEKGD--------SGASGREGRDG-PKGERGAPGILGPQGPPGLPGPVGPP 1898

Query: 1239 GTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G      VPG  G  G     RGE G+ G+ G PG++G
Sbjct: 1899 GQGFPG-VPGGTGPKG----DRGETGSKGEQGLPGERG 1931



 Score =  129 bits (323), Expect = 2e-29
 Identities = 104/303 (34%), Positives = 124/303 (40%), Gaps = 35/303 (11%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P GE G   A G   +G L  A+G + +       ++     +  A  DR    P    G
Sbjct: 2288 PKGEPGPTGAPGQAVVG-LPGAKGEKGAPGGLAGDLV----GEPGAKGDRGLPGPRGEKG 2342

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF--PGPRGPPGVKGEKGDHGL 1112
            E   A           PG PG  G  G PG  G  G+ G   PG  GPPG  G KGD GL
Sbjct: 2343 EAGRA---------GEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393

Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
            PGL G PG  G PG+ G +G  G  G  G  GL GPPG  G  G  G  G  G  GPPG 
Sbjct: 2394 PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453

Query: 1173 VG--------PTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
             G          GLPGP+GERGE G         Q   +              +  +   
Sbjct: 2454 SGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSA 2513

Query: 1225 EQKLEPGTEP--LGSPGTRSKALVPGEWGRGGRHLEG-------RGEPGAVGQMGSPGQQ 1275
              K + G     LG PG R      GE  RG R L+G        G+PG  G  G PG +
Sbjct: 2514 GLKGDKGDSAVILGPPGPRGAKGDMGE--RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDK 2571

Query: 1276 GAS 1278
            G++
Sbjct: 2572 GSA 2574



 Score =  125 bits (315), Expect = 2e-28
 Identities = 107/295 (36%), Positives = 133/295 (45%), Gaps = 52/295 (17%)

Query: 997  GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056
            GE GS P      + RL +  G ++S+      + +IV  +TW DE     LP       
Sbjct: 1934 GEPGSVP-----NVDRLLETAGIKASA------LREIV--ETW-DESSGSFLPV------ 1973

Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVK-GEKGDHGLPGL 1115
             P         S   GPPG +GP G PG  G  G++G PGP+GPPG+  GE+G  G  GL
Sbjct: 1974 -PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGL 2032

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP---PGT 1172
             G PG  GIPG         + G  G  G  G PG RG +G  G RG  G  GP   PGT
Sbjct: 2033 AGEPGKPGIPG---------LPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGT 2083

Query: 1173 VGPTGLPGPK--------GERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
             GP G PGPK        G  GE+G P          ++    S  D   +  R    I 
Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKG------AKGEPGSNGDQGPKGDRGVPGIK 2137

Query: 1225 EQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQGA 1277
              + EPG     G+PG   +  + G  G+ G  L+G RG PG VG  G PG  GA
Sbjct: 2138 GDRGEPGPRGQDGNPGLPGERGMAGPEGKPG--LQGPRGPPGPVGGHGDPGPPGA 2190



 Score =  124 bits (312), Expect = 4e-28
 Identities = 91/228 (39%), Positives = 103/228 (45%), Gaps = 53/228 (23%)

Query: 1071 PGPPGPQGP-----------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            PG PGPQGP                 PGLPG+ G+PGEQG   PRGPPG  G KGD G P
Sbjct: 1429 PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG---PRGPPGAIGPKGDRGFP 1485

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG-- 1171
            G  G  G +   G  G  GP G RGL G AG PG  GP G  G  G +G  GE G PG  
Sbjct: 1486 GPLGEAGEK---GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 1172 -TVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228
              VGP  + GPKGE+G+ G   P+    +                 +  R P P L    
Sbjct: 1543 AVVGP-AVAGPKGEKGDVGPAGPRGATGV-----------------QGERGP-PGLVLPG 1583

Query: 1229 EPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            +PG  P G PG R    + G  G  G      G PG  G  G PG  G
Sbjct: 1584 DPG--PKGDPGDRGPIGLTGRAGPPG----DSGPPGEKGDPGRPGPPG 1625



 Score =  124 bits (312), Expect = 4e-28
 Identities = 89/228 (39%), Positives = 104/228 (45%), Gaps = 29/228 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPG +G  GLPG  G PG  GFPG  GP G  G+ G  G  GL G PG +GIPG +G 
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP 2441

Query: 1131 QGPKGMRGLEGTAGLPGP--------PGPRGFQGMAGARGTSGE---------RGPPGTV 1173
             GP G  G  G +GL G         PGPRG +G  G RG  G           GPPG+ 
Sbjct: 2442 PGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSR 2501

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G  G  G  G KG+    A +  L       +K D      R P  +   K   G  
Sbjct: 2502 GERGEKGDVGSAGLKGDKGDSAVI--LGPPGPRGAKGDM---GERGPRGLDGDKGPRGDN 2556

Query: 1234 PLGSPGTRSKALVPGEWGRGG----RHLEG-RGEPGAVGQMGSPGQQG 1276
              G PG +     PG+ G  G    R L G +G+PGA G  G PG  G
Sbjct: 2557 --GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602



 Score =  122 bits (306), Expect = 2e-27
 Identities = 83/220 (37%), Positives = 101/220 (45%), Gaps = 30/220 (13%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            S+  PG  G  GP G PG  G PG+ G PG  G PG++GEKGD G  G +G  G +G+ G
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKG 2632

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP------TGLPG 1180
              GL G KG +G  G  G PG  G +G  G  G  G SG  G  G +GP       G PG
Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692

Query: 1181 PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240
            PKG++GEKGE                +  F     N     P       PG  P GS G 
Sbjct: 2693 PKGDQGEKGE-----------RGTPGIGGFPGPSGNDGSAGP-------PG--PPGSVGP 2732

Query: 1241 RSKALVPGEWGR----GGRHLEGRGEPGAVGQMGSPGQQG 1276
            R    + G+ G     G R +   G PGA G+ G  G+ G
Sbjct: 2733 RGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPG 2772



 Score =  122 bits (305), Expect = 3e-27
 Identities = 95/253 (37%), Positives = 113/253 (44%), Gaps = 53/253 (20%)

Query: 1071 PGPPGPQGP------------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL 1112
            PGPPGP GP                  PGLPG+ G  G +G PG RGP G KG++GD G 
Sbjct: 1621 PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE 1680

Query: 1113 PGLQGHPGHQGIPGRVGLQGPKGM-------------RGLEGTAGLPGPPGPRGFQGMAG 1159
             G  G PG  G  G  G  GP G              +G  G  G  GP GP+G  G+ G
Sbjct: 1681 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG 1740

Query: 1160 A---RGTSGERGPPGTVGPTGLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFD 1211
            A   RG  G RGPPG  G  G+ GP GE+G++G P       L         +       
Sbjct: 1741 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800

Query: 1212 SFHENTRPPMPIL--EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR----GEPGA 1265
               +  R  +P L  EQ L PG  P G PG   K   PGE G+ G  L G+    G+PG 
Sbjct: 1801 KAGDPGRDGLPGLRGEQGL-PG--PSGPPGLPGK---PGEDGKPG--LNGKNGEPGDPGE 1852

Query: 1266 VGQMGSPGQQGAS 1278
             G+ G  G  GAS
Sbjct: 1853 DGRKGEKGDSGAS 1865



 Score =  119 bits (299), Expect = 1e-26
 Identities = 92/238 (38%), Positives = 111/238 (46%), Gaps = 40/238 (16%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG 1129
            +PG  GP+GP   PG  G  G++GFPGP G  G KGE+G  G  G +G PG  G PG  G
Sbjct: 1463 SPGEQGPRGP---PGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKG 1519

Query: 1130 LQGPKGMRGLEGTAGLPGPP-----------GPRGFQ------GMAGARGTSGERGPPGT 1172
             +GP G  G +G  G PG P           GP+G +      G  GA G  GERGPPG 
Sbjct: 1520 PEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL 1579

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228
            V P G PGPKG+ G++G                   K D       PP P+  +      
Sbjct: 1580 VLP-GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG--PPGPVGPRGRDGEV 1636

Query: 1229 -EPGTE-PLGSPGTRSKALVPGEWG-RGGRHLEG-------RGEPGAVGQMGSPGQQG 1276
             E G E P G PG   KA   GE G RG   + G       +G+PG  G+ GSPG  G
Sbjct: 1637 GEKGDEGPPGDPGLPGKA---GERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSG 1691



 Score =  118 bits (296), Expect = 3e-26
 Identities = 89/223 (39%), Positives = 102/223 (45%), Gaps = 21/223 (9%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP+G PG  G  G  G  G PG  GPPG KG+ G  G PG  G  G  G  G  G 
Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
            +GP G  GL G AG  G  G  G +G  G +G  G+ G  G  G  G  GPKG+RGE G 
Sbjct: 1642 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP 1701

Query: 1191 PQSLATLYQLVSQASHVSK-FDSFHENTRPPM--PIL-----EQKLE-----PGTEPLGS 1237
            P     L      A    +  D   E  R P   P L     E+ +E     PG  P G 
Sbjct: 1702 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG--PQGD 1759

Query: 1238 PGTRSKALVPGEWGRGGRHLEGR----GEPGAVGQMGSPGQQG 1276
            PG R  A   G+  RG   L+GR    G+PGA G  G  G  G
Sbjct: 1760 PGVRGPAGEKGD--RGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800



 Score =  115 bits (289), Expect = 2e-25
 Identities = 98/284 (34%), Positives = 122/284 (42%), Gaps = 62/284 (21%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLP---------GRNGTPGEQGFPGPRG 1099
            P    G+  P  ++  +      GPPG +G PG P         GR+G  GE+G  GP G
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646

Query: 1100 PPGVKGEKGDHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP- 1146
             PG+ G+ G+ GL G             QG PG  G  G  G  GPKG RG  G  G P 
Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG 1706

Query: 1147 ---------------------GPPGPRGFQGMAGA---RGTSGERGPPGTVGPTGLPGPK 1182
                                 GP GP+G  G+ GA   RG  G RGPPG  G  G+ GP 
Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 1183 GERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPIL--EQKLEPGTEPL 1235
            GE+G++G P       L         +          +  R  +P L  EQ L PG  P 
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGL-PG--PS 1823

Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGR-GEPGAVGQMGSPGQQGAS 1278
            G PG   K   PGE G+ G  L G+ GEPG  G+ G  G++G S
Sbjct: 1824 GPPGLPGK---PGEDGKPG--LNGKNGEPGDPGEDGRKGEKGDS 1862



 Score =  115 bits (288), Expect = 3e-25
 Identities = 128/482 (26%), Positives = 198/482 (41%), Gaps = 26/482 (5%)

Query: 364  PRQGPAAAPALDTLPAPTSLV--LSQVTSSS--IRLSWTPAPRHPLKYLIVWRASRGGTP 419
            PR+G A+   +   P     V  L  V S +  +R++W P P     + I W    G   
Sbjct: 581  PREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGAS-GFRISWSTGSGPES 639

Query: 420  REVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479
             + +     A T++  L   T Y V+V  +     G     +  T PL P R + +   +
Sbjct: 640  SQTLPPDSTA-TDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQAS 698

Query: 480  PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQS- 538
              +V +TW    GAT Y  R S  S  G E+ + V        LDGLEP  +Y V V++ 
Sbjct: 699  SSSVTITWTRVPGATGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAH 756

Query: 539  LRGPEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGG 597
            + G +G  A  +    P  +     L   + S D  R+ W G        R+ +  SEGG
Sbjct: 757  VAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAY-RLAWGRSEGG 815

Query: 598  HSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT--KKAPSPSQLSM 655
                   PGN  SA +  L    +Y+VRVT L      + ++  VTT  +  P+   L +
Sbjct: 816  PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHV 875

Query: 656  TELPGDAVQLAWVAAAPS-GVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYD 714
             +    +++L W     + G L++   W P G  +   +  P  L +  L GL   T+Y 
Sbjct: 876  VQRGEHSLRLRWEPVPRAQGFLLH---WQPEGGQEQSRVLGP-ELSSYHLDGLEPATQYR 931

Query: 715  VTILAYYRDGARSDPVSLRYTPSTVS-RSPPSNLALASETPDSLQVSWTPPLGRVLHYWL 773
            V +      G   +  S   T  T S R P   L +   + DS+ ++WT P+ R   Y L
Sbjct: 932  VRLSVL---GPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWT-PVSRASSYIL 987

Query: 774  TYAPASGLG---PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTA 830
            ++ P  G G   P    ++PG  S   +  L+    Y   ++ +    R    S T    
Sbjct: 988  SWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV 1047

Query: 831  CP 832
            CP
Sbjct: 1048 CP 1049



 Score =  114 bits (285), Expect = 6e-25
 Identities = 85/238 (35%), Positives = 101/238 (42%), Gaps = 42/238 (17%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPG-----------------------PRGPPGVKGEK 1107
            PG  GP+GPPG  GR G  GE G PG                       PRG  GV+GE+
Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574

Query: 1108 GDHGL-----PGLQGHPGHQG---IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159
            G  GL     PG +G PG +G   + GR G  G  G  G +G  G PGPPGP G +G  G
Sbjct: 1575 GPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
              G  G+ GPPG     GLPG  GERG +G P     + +   Q           E+ R 
Sbjct: 1635 EVGEKGDEGPPGD---PGLPGKAGERGLRGAPGVRGPVGEKGDQGDP-------GEDGRN 1684

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
              P          EP G PG   + +  G   R       RG+ G  G  G PG  GA
Sbjct: 1685 GSPGSSGPKGDRGEP-GPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGA 1741



 Score =  110 bits (276), Expect = 7e-24
 Identities = 67/150 (44%), Positives = 74/150 (49%), Gaps = 22/150 (14%)

Query: 1063 ACSCSSET--PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV------KGEKGDHGLPG 1114
            AC    E    G  GP G PGL G  G  GE G PG  G PG       KG++G  G PG
Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG------PRGFQGMAGARGTSGER- 1167
             +G  G +G  G  G+ G  G  G +G+AG PGPPG      P G QG  G RG  GER 
Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752

Query: 1168 -------GPPGTVGPTGLPGPKGERGEKGE 1190
                   G PG  G  G PGP G RGEKGE
Sbjct: 2753 VGAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782



 Score =  106 bits (265), Expect = 1e-22
 Identities = 79/239 (33%), Positives = 108/239 (45%), Gaps = 62/239 (25%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGE---KGDHGLPGLQGH--------- 1118
            PGP G +G PG+ G +G PG++G  G  GPPG +GE   KGD G  GL+G          
Sbjct: 2468 PGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILG 2527

Query: 1119 -PGHQGIPGRVGLQGPKGMRGLEG------------TAGLPGP------PGPRGFQGMAG 1159
             PG +G  G +G +GP+G+ G +G            + G PG       PG RG  G  G
Sbjct: 2528 PPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG 2587

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKG--EPQSLATLYQLVSQASHVSKFDSFHENT 1217
              G +G  G PG+ G  G+PG +GE+G+ G   P+ L                       
Sbjct: 2588 QPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG--------------------- 2626

Query: 1218 RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                   E+ ++      G  G + +A  PG  G  G H    GEPG  GQ G+PG++G
Sbjct: 2627 -------ERGVKGACGLDGEKGDKGEAGPPGRPGLAG-HKGEMGEPGVPGQSGAPGKEG 2677



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 52/122 (42%), Positives = 60/122 (49%), Gaps = 14/122 (11%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI------ 1124
            PG PG  G PG  G  G  G++GF G  GP G +GEKG+ G PG+ G PG  G       
Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGPR--------GFQGMAGARGTSGERGPPGTVGPT 1176
            PG  G  GP+G  GL+G  G  GPPG R        G  G  G +G  G  GP G  G  
Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783

Query: 1177 GL 1178
             L
Sbjct: 2784 AL 2785



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 40/81 (49%), Positives = 46/81 (56%), Gaps = 5/81 (6%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG--LQGHPGHQGIPGR 1127
            TPG  G  GP G  G  G PG  G  GPRGP G++G+KG+ G PG  + G PG  G PG 
Sbjct: 2705 TPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGE 2764

Query: 1128 VGLQG---PKGMRGLEGTAGL 1145
             G QG   P G RG +G A L
Sbjct: 2765 RGEQGRPGPAGPRGEKGEAAL 2785



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 77/263 (29%), Positives = 117/263 (44%), Gaps = 30/263 (11%)

Query: 612 TLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAA 671
           TL PL S      R  C   GG   T   R       +P  L ++E    ++++ W AA+
Sbjct: 206 TLLPLVS------RRVCTTAGGVPVT---RPPDDSTSAPRDLVLSEPSSQSLRVQWTAAS 256

Query: 672 PSGVLVYQITWTPL-GEGKA-----HEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
              V  Y++ +TPL G G+       E++VP    +  L GL   TEY VT++A Y   A
Sbjct: 257 -GPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALY---A 312

Query: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
            S   ++  T  T +   P  L + + T  SL V+W    G    Y +T+   SG GP +
Sbjct: 313 NSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGAT-GYRVTWRVLSG-GPTQ 369

Query: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTAC---PALRPDGSLPG 842
              +   +  V L DL+  T Y V VS ++      A S   +T       LRP   L  
Sbjct: 370 QQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-VILGP 428

Query: 843 FDLMVAFSLVEKAYASIRGVAME 865
             ++++++LV +A    RG  +E
Sbjct: 429 TSILLSWNLVPEA----RGYRLE 447



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 99/387 (25%), Positives = 149/387 (38%), Gaps = 47/387 (12%)

Query: 24   EQVQASGLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVG 83
            E   A G L +    E  L+++W E      G+L+  +P  G  EQ  +L  +     + 
Sbjct: 865  EAPPALGTLHVVQRGEHSLRLRW-EPVPRAQGFLLHWQPEGGQ-EQSRVLGPELSSYHLD 922

Query: 84   GLSPSKGYTLQIFELTGSGRF----LLARREFV-IEDLKSSSLDRS-------------- 124
            GL P+  Y +++  L  +G      + AR E   +  ++   +D S              
Sbjct: 923  GLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRA 982

Query: 125  -----SQRPLGS------GAPEPTPSHTGSPDPEQASEPQVAFTPSQDPRTPA--GP--- 168
                 S RPL        G+P+  P  + S       EP V++  S  P      GP   
Sbjct: 983  SSYILSWRPLRGPGQEVPGSPQTLPGISSS-QRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041

Query: 169  --QFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGD 226
              Q    P   AD+VFL   +    H      +     V+A   +GP  VQVGL  YS  
Sbjct: 1042 VTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHR 1101

Query: 227  AQTEWDLNSLSTKEQVLAAVRRLRY---KGGNTFTGLALTHVLGQNLQP-AAGLRPEAAK 282
                + LN       +L  +R + Y    G N  T +   H     L P A G R     
Sbjct: 1102 PSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAH--RYMLAPDAPGRRQHVPG 1159

Query: 283  VVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDI-TVHSVLDF 341
            V++L+ D   + D+ +  R  +  G+NV  +G+  AD  +LR LA     + T  +V D 
Sbjct: 1160 VMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDG 1219

Query: 342  LQLGALAGLLSRLICQRLQGGSPRQGP 368
              L      L+  +CQ      PR  P
Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRPEP 1246



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 44/151 (29%), Positives = 54/151 (35%), Gaps = 51/151 (33%)

Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---GPTGLPGPKGERGEKG 1189
            PKG +G  G  GL G  GP G  G+ G  G  G +GPPG+    G  G PG  G  G  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
               +                                    PGT   G+PG +    +PG 
Sbjct: 1312 RAGN------------------------------------PGTP--GAPGLKGSPGLPGP 1333

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280
                      RG+PG  G  G  G+ GA  Q
Sbjct: 1334 ----------RGDPGERGPRGPKGEPGAPGQ 1354



 Score = 34.7 bits (78), Expect = 0.60
 Identities = 30/85 (35%), Positives = 36/85 (42%), Gaps = 19/85 (22%)

Query: 1212 SFHENTRP-PMPIL---EQKLEPG-------TEPLGSPGTRSKALVPGEWG-------RG 1253
            SF    RP P P+     QK EPG         P G PG   +   PG  G       +G
Sbjct: 1237 SFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKG 1296

Query: 1254 GRHLEGR-GEPGAVGQMGSPGQQGA 1277
             R   G  G PG+ G+ G+PG  GA
Sbjct: 1297 ERGFPGADGRPGSPGRAGNPGTPGA 1321


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
            sapiens]
          Length = 921

 Score =  208 bits (529), Expect = 3e-53
 Identities = 155/472 (32%), Positives = 212/472 (44%), Gaps = 57/472 (12%)

Query: 827  GQTACPALR-PDGSLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTR 885
            G   CP +R     LPGFDL+  F  V+KA AS R +     +      + L  +     
Sbjct: 40   GNELCPKIRIGQDDLPGFDLISQFQ-VDKA-ASRRAIQRVVGSATLQVAYKLGNNVDFRI 97

Query: 886  RVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFH 945
               ++YP+ LP E++ +   R+   T ++ + +WQ+     +  +G+ ++   +S+ + +
Sbjct: 98   PTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSY 157

Query: 946  RDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAA 1005
            +    +LQ A F    +  +F   +HK+ + V RS   L+VDC ++   P+   G     
Sbjct: 158  KGLDGSLQTAAFS--NLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDID 215

Query: 1006 GFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFVSACS 1065
            GF  LG+LA    P+ S   F+LQ + I C       + C ELPA              S
Sbjct: 216  GFAVLGKLAD--NPQVS-VPFELQWMLIHCDPLRPRRETCHELPAR----------ITPS 262

Query: 1066 CSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
             +++  GPPG QGPPG PG  G PG  G  G RGP G  G  G  G PG  G PG  G P
Sbjct: 263  QTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTP 322

Query: 1126 GRVGLQGPKGMR---GLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT---------V 1173
            G  GL GP G     G +G  G PG PG RGF G    RG  G  GPPGT         V
Sbjct: 323  GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRV 378

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            GP G PG +G  G  G P    T+               FH+      P+      PG  
Sbjct: 379  GPVGDPGRRGPPGPPGPPGPRGTI--------------GFHDGD----PLCPNACPPGRS 420

Query: 1234 PL-GSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQGASTQGL 1282
               G PG R      GE G  GR  H    G+ G +G++G+ G  GA  QGL
Sbjct: 421  GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA--QGL 470



 Score =  132 bits (333), Expect = 2e-30
 Identities = 96/248 (38%), Positives = 107/248 (43%), Gaps = 42/248 (16%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG------LQGHPGHQG 1123
            +PG PG  GPPGLPG  G  G  G PGP+G  G  GE+G+ G  G      L G  G  G
Sbjct: 647  SPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706

Query: 1124 IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---------- 1173
             PG  GL+GP+G RGL G  G  GPPGPRG QG  GA G  G +GPPG            
Sbjct: 707  NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 766

Query: 1174 --------------------GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
                                G TGLPG  G  G  G P       Q+  +     K    
Sbjct: 767  MRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 826

Query: 1214 HENTRPPMPILEQKLE---PGTEPLGSPGTRSKALVPG--EWGRGGRHLEGRGEPGAVGQ 1268
                R P   L +K E   PG  P G PG       PG   +GR GR  E RG PG  G 
Sbjct: 827  ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGE-RGPPGVAGI 885

Query: 1269 MGSPGQQG 1276
             G PG  G
Sbjct: 886  PGVPGPPG 893



 Score =  129 bits (325), Expect = 1e-29
 Identities = 92/253 (36%), Positives = 112/253 (44%), Gaps = 47/253 (18%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            S+  PG PG  G  G PG+ G PGE G  GP+G PG +GE G  G PGL G  G  G PG
Sbjct: 590  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP----------------- 1169
              GL GP G+ G++G  G+ G PGP+G QG +G  G +GERG                  
Sbjct: 650  LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709

Query: 1170 -------------PGTVGPTGLPGPKGERGEKGE--------PQSLATLYQLVSQASHVS 1208
                         PG  GP G PGP+G +GE+G         P   A   Q + Q     
Sbjct: 710  EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769

Query: 1209 KFDSFHENT----RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEP 1263
              + F E      RP          PG  P G PG   +   PG+ G  G  L G +G P
Sbjct: 770  IQEHFAEMAASLKRPDSGATGLPGRPG--PPGPPGPPGENGFPGQMGIRG--LPGIKGPP 825

Query: 1264 GAVGQMGSPGQQG 1276
            GA+G  G  G  G
Sbjct: 826  GALGLRGPKGDLG 838



 Score =  129 bits (323), Expect = 2e-29
 Identities = 86/218 (39%), Positives = 107/218 (49%), Gaps = 15/218 (6%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PG QG  G PG  G  G++G  G RG PG+ G KGD GLPG+ G  G  G+PG  G 
Sbjct: 498  PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLP---GPKGE--- 1184
             G  G  G  G  GLPG PG  G +G+AG +G++G  G PG +G +G P   GP GE   
Sbjct: 558  PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMP----ILEQKLEPGTEPLGSPGT 1240
            RG +G P S   L   V       K  S      P +P    +   K + G   +G PG 
Sbjct: 618  RGPQGLPGSRGELGP-VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGP 674

Query: 1241 RSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQG 1276
            + +    GE G  G    L   G PG  G  G+PG+ G
Sbjct: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 712



 Score =  127 bits (319), Expect = 7e-29
 Identities = 92/240 (38%), Positives = 110/240 (45%), Gaps = 37/240 (15%)

Query: 1053 DGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGD 1109
            DGE  P  +          GPPG  GP G  G  G  G  G PGP+G    PGV G  G 
Sbjct: 489  DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTS---GE 1166
             G+PG +G PG  G PG  GLQG  G+ G+ G  G+ G  G  G  G  G  G S   G+
Sbjct: 549  PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 608

Query: 1167 RGPPGTV---GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPI 1223
            +GPPG V   GP GLPG +GE G  G P     L  L S                P +P 
Sbjct: 609  QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS----------------PGLPG 652

Query: 1224 LEQKLEPGTEPLGSPGTRSKALVPGEWG----RGGRHLEGR-GEPGAVGQMGSPGQQGAS 1278
            L     PG  P G PG +    V GE G    +G    EG  GE G +G +G PG +G++
Sbjct: 653  L-----PG--PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 705



 Score =  124 bits (312), Expect = 4e-28
 Identities = 96/251 (38%), Positives = 107/251 (42%), Gaps = 69/251 (27%)

Query: 1071 PGPPGPQGPPGLPGRNGT---------------PGEQGFPGPRGPPGVKGEKGDHGLPGL 1115
            PG  GP GPPG PG  GT               PG  G+PG  G  G KG KG+ G PG 
Sbjct: 384  PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 443

Query: 1116 QGHPGH---QGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------QGMAGARGT 1163
            QGH G    QG  G VG QGP G +GL G  G+ G  G +G          QG+ GA G 
Sbjct: 444  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503

Query: 1164 SGERGPPGTVGPTG------------LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFD 1211
             G+RGPPG  GP G            LPGPKG+ G  G                 V   D
Sbjct: 504  QGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG-----------------VDGRD 546

Query: 1212 SFHENTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLE-----GRGEPGA 1265
                   P MP    K EPG   P G  G +    VPG  G  G   E       G+PG 
Sbjct: 547  GI-----PGMP--GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599

Query: 1266 VGQMGSPGQQG 1276
            +G  G PGQQG
Sbjct: 600  MGNSGKPGQQG 610



 Score =  104 bits (259), Expect = 6e-22
 Identities = 61/125 (48%), Positives = 66/125 (52%), Gaps = 13/125 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP GPPG       PGE GFPG  G  G+ G KG  G  GL+G  G  G  G  G 
Sbjct: 792  PGRPGPPGPPG------PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGP 845

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG- 1189
             G +G  GL G  GLPG PGP  +    G  G  GERGPPG  G  G+PGP G  G  G 
Sbjct: 846  PG-RGPNGLPGAIGLPGDPGPASY----GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900

Query: 1190 -EPQS 1193
             EP S
Sbjct: 901  CEPAS 905



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 33/80 (41%), Positives = 38/80 (47%), Gaps = 2/80 (2%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPG +GP GLPG  G PG+ G P   G  G  GE+G  G+ G+ G PG  G PG  G  
Sbjct: 844  GPPG-RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901

Query: 1132 GPKGMRGLEGTAGLPGPPGP 1151
             P       G       P P
Sbjct: 902  EPASCTMQAGQRAFNKGPDP 921


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score =  183 bits (465), Expect = 8e-46
 Identities = 144/496 (29%), Positives = 213/496 (42%), Gaps = 67/496 (13%)

Query: 828  QTACPALRPDGSLP--GFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDAQLTR 885
            ++ CP   P  +    GFD+++   + +K    I+   + P    G   + +     L+ 
Sbjct: 214  ESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQ---LSPKKIKG---YEVTSKVDLSE 267

Query: 886  RVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSLTYFH 945
              S+V+P  LPP +  V   R      ++ + LW++   D +P + V L+   K L +  
Sbjct: 268  LTSNVFPEGLPPSYVFVSTQRF---KVKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTT 324

Query: 946  RDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGSPPAA 1005
                   Q  TF   +V+ +F   +H++ + V    V LY+D +++  +PL      P  
Sbjct: 325  TSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLH-----PVL 379

Query: 1006 GFVTLGR--LAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETC--PAFV 1061
            G +  G+  + K  G +  +  F +Q L+I C     + +  CE+P   +GE    P+ V
Sbjct: 380  GILINGQTQIGKYSG-KEETVQFDVQKLRIYCDPEQNNRETACEIPGF-NGECLNGPSDV 437

Query: 1062 SA----CSCSSETPGPPGPQGPPGLPGRNGTPGE-------------------------- 1091
             +    C C    PG  GP+G PGLPG  G PG+                          
Sbjct: 438  GSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG 497

Query: 1092 -QGFPGPRGPPGVKGEKGD---------HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEG 1141
             +G PG +G PG  G+KGD         HG+PG +G  G +G  G  G  G KG +G +G
Sbjct: 498  ARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKG 557

Query: 1142 TAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLV 1201
             AG PG PGP G  G  G  G  G  G  G  G  G PG  G RGE G P        L+
Sbjct: 558  NAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIP-GFPGNRGLM 616

Query: 1202 SQASHVSKFDSFHENTRPPMP-ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGR 1260
             Q   +       +   P MP ++     PG    G+PG++     PG  G  G     +
Sbjct: 617  GQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQP--GTPGSKGSKGEPGIQGMPGAS-GLK 673

Query: 1261 GEPGAVGQMGSPGQQG 1276
            GEPGA G  G PG  G
Sbjct: 674  GEPGATGSPGEPGYMG 689



 Score =  125 bits (314), Expect = 3e-28
 Identities = 77/206 (37%), Positives = 99/206 (48%), Gaps = 12/206 (5%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP G PG  G++G  G  GF G  G PG  G+ G  G PG+ G PG++G+ G+ G 
Sbjct: 562  PGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGE 621

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             GP G +G +G  G+PG  G  G  G  G  G+ G +G PG  G  G  G KGE G  G 
Sbjct: 622  IGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGS 681

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEW 1250
            P     +     Q     K +   +       I  QK E G +  G PG +    + G  
Sbjct: 682  PGEPGYMGLPGIQGKKGDKGNQGEKG------IQGQKGENGRQ--GIPGQQG---IQGHH 730

Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G  G   E +GEPG  G +GS G+ G
Sbjct: 731  GAKGERGE-KGEPGVRGAIGSKGESG 755



 Score =  124 bits (312), Expect = 4e-28
 Identities = 70/196 (35%), Positives = 113/196 (57%), Gaps = 6/196 (3%)

Query: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236
           P D+VF++DGS+S+G  +F+ VK +L ++   F+IGP  +QVG+ QYS     E  L S 
Sbjct: 35  PTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSY 94

Query: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDV 296
            + E + AAV  + Y GGNT TG A+   L      ++       K+ +++TDGKSQDDV
Sbjct: 95  DSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVLTDGKSQDDV 151

Query: 297 HTAARVLKDLGVNVFAVGV-KNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355
             AA+  +D  + +FA+GV    ++AELR +A+ P    V  V D++ +  +  ++ + +
Sbjct: 152 KDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKL 211

Query: 356 CQRLQGGSPRQGPAAA 371
           C+  +   P + P AA
Sbjct: 212 CE--ESVCPTRIPVAA 225



 Score =  121 bits (304), Expect = 4e-27
 Identities = 74/207 (35%), Positives = 99/207 (47%), Gaps = 6/207 (2%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG 1129
            +PG  G  G PG PG++GT GE G PG  G  G+ G+KG+ G PG QG  G  G+PG +G
Sbjct: 582  SPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMG 641

Query: 1130 LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG 1189
              G  G  G  G+ G  G PG +G  G +G +G  G  G PG  G  GLPG +G++G+KG
Sbjct: 642  SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
                     Q               +          +K EPG    G+ G++ ++ V G 
Sbjct: 702  NQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVR--GAIGSKGESGVDGL 759

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             G  G     +G+PG  G  G PG  G
Sbjct: 760  MGPAG----PKGQPGDPGPQGPPGLDG 782



 Score =  116 bits (291), Expect = 1e-25
 Identities = 81/226 (35%), Positives = 111/226 (49%), Gaps = 22/226 (9%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG  G +G PG  G  G PG  G PG +G  G KG +G+ G+ G +G  G QGIPG+ G+
Sbjct: 667  PGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI 726

Query: 1131 Q---GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187
            Q   G KG RG +G  G+ G  G +G  G+ G  G +G +G PG  GP G PG  G+ G 
Sbjct: 727  QGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGR 786

Query: 1188 KGEPQSLATL--------YQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSP 1238
            +   Q +  +          ++ Q+  +   D    ++  P +P     + P   P G P
Sbjct: 787  EFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGP-EGPRGLP 845

Query: 1239 GTRSKALVPGEWG-------RGGRHLEGR-GEPGAVGQMGSPGQQG 1276
            G   +  VPG  G       RG + L GR GE G+ G  G PG+QG
Sbjct: 846  GLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-FGYPGEQG 890



 Score =  115 bits (289), Expect = 2e-25
 Identities = 70/172 (40%), Positives = 84/172 (48%), Gaps = 11/172 (6%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPG QG  G PG  G  G  G PG  G PG KG KG+ G+ G+ G  G +G PG  G  
Sbjct: 623  GPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSP 682

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G  G  GL G  G  G  G +G +G+ G +G +G +G PG  G  G  G KGERGEKGEP
Sbjct: 683  GEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEP 742

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243
                 +          SK +S  +    P     Q  +PG  P G PG   K
Sbjct: 743  GVRGAI---------GSKGESGVDGLMGPAGPKGQPGDPG--PQGPPGLDGK 783



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 63/155 (40%), Positives = 73/155 (47%), Gaps = 45/155 (29%)

Query: 1071 PGPPGPQGPPGLPGRNGTP----------------------------------GEQGFPG 1096
            PG PGPQGPPGL G+ G                                     + G PG
Sbjct: 769  PGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPG 828

Query: 1097 PRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQG 1156
              GPPG  G +G  GLPGL   PG  G+PG VG+ G  G+RGL+G   LPG  G +G QG
Sbjct: 829  IPGPPGPIGPEGPRGLPGL---PGRDGVPGLVGVPGRPGVRGLKG---LPGRNGEKGSQG 882

Query: 1157 MAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
                 G  GE+GPPG  GP G PG   E G  G+P
Sbjct: 883  F----GYPGEQGPPGPPGPEGPPGISKE-GPPGDP 912



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 54/124 (43%), Positives = 63/124 (50%), Gaps = 15/124 (12%)

Query: 1064 CSCSSETPGPPGPQGP---------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
            C     +PG PGP GP         PGLPGR+G PG  G PG  G  G+KG  G +G  G
Sbjct: 820  CLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKG 879

Query: 1115 LQ--GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
             Q  G+PG QG PG  G +GP G+       G PG PG  G  G  G  G  G+ GPPG 
Sbjct: 880  SQGFGYPGEQGPPGPPGPEGPPGI----SKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGI 935

Query: 1173 VGPT 1176
              P+
Sbjct: 936  CDPS 939



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 54/113 (47%), Positives = 58/113 (51%), Gaps = 6/113 (5%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPGP GP G  G  G PG  G PG  G PG  G +G  GLPG  G  G QG  G  G 
Sbjct: 830  PGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-GYPGE 888

Query: 1131 QGPKGMRGLEGTAGLP--GPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP 1181
            QGP G  G EG  G+   GPPG  G  G  G  G  G +G PG   P G+  P
Sbjct: 889  QGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPG---PPGICDP 938


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  182 bits (462), Expect = 2e-45
 Identities = 153/533 (28%), Positives = 221/533 (41%), Gaps = 100/533 (18%)

Query: 817  AGRSEAVSATGQTACPALRPDG-----------SLPGFDLMVAFSLVEKAYASIRGVAME 865
            A  S  V    + +CP LR +G            + GFDL  +FSL      S +     
Sbjct: 20   ASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----- 74

Query: 866  PSAFGGTPTFTLFK--DAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTA 923
                      T FK   A L R    ++P  LP E+++  + R+     +E + LWQ+  
Sbjct: 75   ----------TCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLN 124

Query: 924  EDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVR 983
            +   P + +++D GKK + +  +     +    F  +E+R +F   +HK+ +++    + 
Sbjct: 125  QQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVIS 184

Query: 984  LYVDCRKVAERPLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADED 1043
            LY+DC  +A R   E  +    G   +   A    P       +L  L+I CS     ++
Sbjct: 185  LYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKP----VDIELHQLKIYCSANLIAQE 240

Query: 1044 RCCELPASRD------GETCPAFVSA------------------CSCSSE--------TP 1071
             CCE+  ++       G    ++V+A                  C C            P
Sbjct: 241  TCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAP 300

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---------KGEKGDHGLPGLQGHPGHQ 1122
            G PG +G  G PG NG  G  GFPG +G  G          KGE+G+ G P L G  G  
Sbjct: 301  GSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGEN 360

Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPP---------GPRGFQGMAGARGTSGERGPPGTV 1173
            G+ G +G  GP G +G +G  G PGPP         GP+G  G  G RG  G+ GPPG  
Sbjct: 361  GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP 420

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFH----ENTRPPMP----ILE 1225
            GP   PGP G  G +G  Q+L   Y   ++ +   +         E   P  P       
Sbjct: 421  GP---PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKG 477

Query: 1226 QKLEPGTEPL--GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            QK EPG EP   G  G R +  V G  G  G      G+PG  G +GSPG +G
Sbjct: 478  QKGEPG-EPFTKGEKGDRGEPGVIGSQGVKGE----PGDPGPPGLIGSPGLKG 525



 Score =  132 bits (331), Expect = 3e-30
 Identities = 92/239 (38%), Positives = 116/239 (48%), Gaps = 19/239 (7%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            G+  PA     +  S  PG PGP G PG PG  G  G+ GFPGP GP G  G  G  G+P
Sbjct: 875  GDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            G       QGI G+ G +GPKG RG +G  G  G  G RG  G+ G +G  G  GPPG  
Sbjct: 935  GA------QGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988

Query: 1174 GPTGLPGPKGERGEKGEP--QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP- 1230
            G  G PG +G  G  G P   + A  ++ + +  +      F E  R  + + + KL   
Sbjct: 989  GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEE--RMAVFLSQLKLPAA 1046

Query: 1231 --GTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQGASTQGL 1282
                +  G PG   K  +PG  G    +G R  +G RGEPG +G  GSPG  G S  GL
Sbjct: 1047 MLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGL 1104



 Score =  127 bits (320), Expect = 5e-29
 Identities = 91/236 (38%), Positives = 104/236 (44%), Gaps = 35/236 (14%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLP--GRNGTPG---------EQGFPGPRGP 1100
            R G   P        S   PG PGP GPPG+P   RNG               +PGP GP
Sbjct: 787  RTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGP 846

Query: 1101 PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA 1160
            PG KG+ G  G PG  G PG +G PG  G +GP G  G+ G +G PG PGP G  G  G 
Sbjct: 847  PGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGE 906

Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP 1220
            RG  G+ G PG  GP+G PG  G+ G  G            +Q       D   +  R  
Sbjct: 907  RGPVGDIGFPGPEGPSGKPGINGKDGIPG------------AQGIMGKPGDRGPKGERGD 954

Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              I      PG    GS G R K   PG  G  G  +   G PG  G MGSPG QG
Sbjct: 955  QGI------PGDR--GSQGERGK---PGLTGMKGA-IGPMGPPGNKGSMGSPGHQG 998



 Score =  119 bits (298), Expect = 2e-26
 Identities = 85/232 (36%), Positives = 104/232 (44%), Gaps = 43/232 (18%)

Query: 1071 PGPPGPQGPPGLPGRN-----------------------GTPGEQGFPGPRGPPGVKGEK 1107
            PGPPGP GPPG+ G +                       G  GE G PG  G  G KG+K
Sbjct: 420  PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQK 479

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER 1167
            G+ G P  +G  G +G PG +G QG KG  G  G  GL G PG +G QG AG+ G  G  
Sbjct: 480  GEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP 539

Query: 1168 GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQK 1227
            G  G  G  G+PG +G +GEKG+P  +     L                  PP   L   
Sbjct: 540  GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAG----------PPGKSLPG- 588

Query: 1228 LEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQ--MGSPGQQGA 1277
             EPG +  G+PG        GE G  G H    G PG +G   +G PG+ GA
Sbjct: 589  -EPGLD--GNPGAPGPRGPKGERGLPGVH----GSPGDIGPQGIGIPGRTGA 633



 Score =  117 bits (294), Expect = 5e-26
 Identities = 95/266 (35%), Positives = 110/266 (41%), Gaps = 64/266 (24%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRG-------PPGVKGEKGDHGLPG--LQG 1117
            S+ + GP GP G  GLPG +G PG+QG  G +G       PPG+ G KG+ G PG  L G
Sbjct: 529  SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPG 588

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPG-----------------PPGPRGFQGMAGA 1160
             PG  G PG  G +GPKG RGL G  G PG                 P G  G QG  G 
Sbjct: 589  EPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGL 648

Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQL-------------------- 1200
             G  G  G PG  G  G  G  G  G  G+P +L  L  +                    
Sbjct: 649  PGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKS 708

Query: 1201 ----VSQASHVSKFDSFHE----NTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWG 1251
                   A    K+DS         R P  I      PG E P GS G R    +PGE  
Sbjct: 709  NKGEEGGAGEPGKYDSMARKGDIGPRGPPGI------PGREGPKGSKGERGYPGIPGE-- 760

Query: 1252 RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
            +G   L+G  G PGA G  G PG  G
Sbjct: 761  KGDEGLQGIPGIPGAPGPTGPPGLMG 786



 Score =  115 bits (289), Expect = 2e-25
 Identities = 79/224 (35%), Positives = 110/224 (49%), Gaps = 28/224 (12%)

Query: 1065 SCSSETPG---PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            +C +  PG     G +G  G PG+  +   +G  GPRGPPG+ G +G  G  G +G+P  
Sbjct: 698  NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP-- 755

Query: 1122 QGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP 1181
             GIPG    +G +G++G+ G  G PGP GP G  G  G  G +G +G  G+ GP G PGP
Sbjct: 756  -GIPGE---KGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811

Query: 1182 KGERG-EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240
             G  G    E   +++LY++    +      S+     PP P    K +PG  P+G PG 
Sbjct: 812  PGPPGIPFNERNGMSSLYKIKGGVN----VPSYPGPPGPPGP----KGDPG--PVGEPGA 861

Query: 1241 RSKALVPGEWG-RGGRHLEG-------RGEPGAVGQMGSPGQQG 1276
                 + G  G +G R   G        G+PGA G  G PG+ G
Sbjct: 862  MGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPG 905



 Score =  107 bits (266), Expect = 1e-22
 Identities = 83/227 (36%), Positives = 95/227 (41%), Gaps = 25/227 (11%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P  + GE    F          PG  G QG  G PG  G PG  G PG +G  G  G  G
Sbjct: 475  PKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168
              G PG  G PG  GIPG+ G++G KG  G  G  G PG PGP+G  G  G        G
Sbjct: 535  PRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPG----KSLPG 588

Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-- 1226
             PG  G  G PGP+G +GE+G P              H S  D   +    P     Q  
Sbjct: 589  EPGLDGNPGAPGPRGPKGERGLP------------GVHGSPGDIGPQGIGIPGRTGAQGP 636

Query: 1227 KLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSP 1272
              EPG + P G PG       PG  G  GR     G+PG  G  G P
Sbjct: 637  AGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD----GKPGLPGPPGDP 679



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 64/215 (29%), Positives = 75/215 (34%), Gaps = 87/215 (40%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG---------------- 1114
            PGP GP G PG+ G++G PG QG  G  G  G KGE+GD G+PG                
Sbjct: 916  PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGM 975

Query: 1115 --------------LQGHPGHQGIPGRVGLQG---------------------------- 1132
                            G PGHQG PG  G+ G                            
Sbjct: 976  KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035

Query: 1133 -------------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG-----ERG 1168
                                 G  G +G  G PG PGP+G++G  G RG  G       G
Sbjct: 1036 VFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPG 1095

Query: 1169 PPGTV-----GPTGLPGPKGERGEKGEPQSLATLY 1198
             PGT      G  G PGP+G  G  G       LY
Sbjct: 1096 LPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLY 1130



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 34/82 (41%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 1063 ACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP--------PGVKGEKGDH--GL 1112
            A   +++  G PGP G  GLPG  G PG QG+ G +G         PG  G  G    GL
Sbjct: 1045 AAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGL 1104

Query: 1113 PGLQGHPGHQGIPGRVGLQGPK 1134
            PG  G PG QG PG  G   P+
Sbjct: 1105 PGSPGAPGPQGPPGPSGRCNPE 1126


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  169 bits (429), Expect = 1e-41
 Identities = 143/486 (29%), Positives = 196/486 (40%), Gaps = 71/486 (14%)

Query: 831  CPALRPDGS-----------LPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFK 879
            CP++R +G            + GFDLM  FS+ E       G        G  P      
Sbjct: 223  CPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFP------ 276

Query: 880  DAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKK 939
               + +   DV+P  LP E+  V   R    + +E + +WQ+  +   P + + LD   K
Sbjct: 277  ---VVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENK 333

Query: 940  SLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEM 999
            ++ Y             F    V  +F   +HK+ +++    V L++DC  V   P+ E 
Sbjct: 334  AVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEER 393

Query: 1000 GSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPAS-------- 1051
             +    G   +G+    R   S    F LQ + I C    A+ + CC++P+         
Sbjct: 394  ENIDIQGKTVIGK----RLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVT 449

Query: 1052 ------------RDGETCPAFVSA--CSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGP 1097
                          G     F+    CSC +   G  G  GP GLPG  G   + G  GP
Sbjct: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG---DIGAIGP 506

Query: 1098 RGPPGVKGEKGDHGL----PGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRG 1153
             G PG KGEKGD G+     G +G  G  G+PG  G  G KGMRG  G  G PG PG   
Sbjct: 507  VGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE-- 564

Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
              GM G +G  G  GPPG VG  GL G +GE+G +GE                  K    
Sbjct: 565  -VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL-------DGFPGKPGDT 616

Query: 1214 HENTRP-PMPILEQKLEPG-TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGS 1271
             +  RP P  +   + E G   P G PG      VPG   +       +G PG  G  G+
Sbjct: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPG------VPGSVVQQEGLKGEQGAPGPRGHQGA 670

Query: 1272 PGQQGA 1277
            PG  GA
Sbjct: 671  PGPPGA 676



 Score =  143 bits (360), Expect = 1e-33
 Identities = 90/214 (42%), Positives = 105/214 (49%), Gaps = 16/214 (7%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPGP G PGLPG  G PG+ G PGP GPPG  G  G  G PG +G PG +G  G  G 
Sbjct: 722  PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G +G  G +G AG PG  G  G  G  G  G  GE+G  G  G  GLPG KG+RGEKGE
Sbjct: 782  PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841

Query: 1191 -----PQSLATLYQLVSQASHV-SKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSK 1243
                 P  L     L +    +  +     E   P +P      EPG +   G  G +  
Sbjct: 842  AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP-----GEPGLQGRPGELGPQGP 896

Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
               PG  G+ G H    G PGA G  G+PG  GA
Sbjct: 897  TGPPGAKGQEGAH----GAPGAAGNPGAPGHVGA 926



 Score =  140 bits (352), Expect = 1e-32
 Identities = 109/296 (36%), Positives = 136/296 (45%), Gaps = 17/296 (5%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P G  G P   GF      + A GPR  S A  L   + +      D D     P    G
Sbjct: 1268 PEGARGPP---GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK---DGDTGPTGPQGPQG 1321

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEK---GDHG 1111
               P   +    S   PGP G  G  G  G NG+PG  GF GPRGPPG  GEK   G  G
Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381

Query: 1112 LPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171
            +PG  G PG +G  G  G++G KG  G +G  G PG PG +G  G+ G +G  GE GP  
Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP-- 1439

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQ--ASHVSKFDSFHENTRPPMPILEQKLE 1229
             VGP G PG  G  G +GE  S+ TL +L+ +     +    ++     PP  +   +  
Sbjct: 1440 -VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGR 1498

Query: 1230 PGTE-PLGSPGTRSKALVPGEWGRGGR-HLEGRGEP-GAVGQMGSPGQQGASTQGL 1282
            PG   P G  G   +A   GE GR G+  LEG   P G  G+ G+ G  GA   GL
Sbjct: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGL 1554



 Score =  139 bits (350), Expect = 2e-32
 Identities = 97/283 (34%), Positives = 128/283 (45%), Gaps = 64/283 (22%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG 1111
            +DG+T P             GP GPQGP G PG+NG+PG  G PGP G PG KG KG++G
Sbjct: 1307 KDGDTGPT------------GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354

Query: 1112 LPGLQG---------HPGHQGIPGRVG------------------LQGPKGMRGLEGTAG 1144
             PGL G          PG +G+PG+ G                  ++G KG  G +G  G
Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414

Query: 1145 LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQ----- 1199
             PG PG +G  G+ G +G  GE GP G  GP G PG  G RGE    ++L  L Q     
Sbjct: 1415 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474

Query: 1200 -LVSQASHV------SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG- 1251
             L ++ +++      +   S      PP P  +  L     P+G PG   +  + G  G 
Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534

Query: 1252 ---RGGRHLEG---------RGEPGAVGQMGSPGQQGASTQGL 1282
               +G R  +G         RGE G  G  G PG+ G +  GL
Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL 1577



 Score =  138 bits (347), Expect = 4e-32
 Identities = 75/184 (40%), Positives = 113/184 (61%), Gaps = 3/184 (1%)

Query: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238
           D+VFL+D S S+G   F++V+ ++A+++  FE+GPD+ +VG+ +YS    T ++L    +
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPE---AAKVVILVTDGKSQDD 295
           +E+V AA RRL Y GGNT TG AL ++  ++  P AG RP      +V IL+TDG+SQD 
Sbjct: 98  QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157

Query: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355
           V  AA      G+ +FAVGV  A + EL  +AS P+   V  V DF  +  + G L R +
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217

Query: 356 CQRL 359
           C+ +
Sbjct: 218 CENV 221



 Score =  132 bits (332), Expect = 2e-30
 Identities = 84/221 (38%), Positives = 101/221 (45%), Gaps = 21/221 (9%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQ-------- 1122
            PG PGP G  G+ G  G PG QG PG  GPPG +G  G  G+PG +G  G          
Sbjct: 1197 PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256

Query: 1123 -------GIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
                   G+PG  G +GP G +G  G +G PGP G  G  G+ G  G  G+ G  G  GP
Sbjct: 1257 PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 1316

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G  GP+G  G+ G P S        +     SK     EN  P +P       P  EP 
Sbjct: 1317 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK----GENGSPGLPGFLGPRGPPGEP- 1371

Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G  G   K  VPG+ G  G   E RG+PG  G  G PG +G
Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKGPPGGKG 1411



 Score =  132 bits (331), Expect = 3e-30
 Identities = 97/263 (36%), Positives = 113/263 (42%), Gaps = 39/263 (14%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPG---------RNGTPG--------- 1090
            P   DG    A       S    GPPGPQGP GLPG         R+G PG         
Sbjct: 1202 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 1261

Query: 1091 EQGFPGP---RGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL------------QGPKG 1135
            E G PGP   RGPPG KG  GD G PG +G  G  G+PG+ GL            QGP+G
Sbjct: 1262 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 1321

Query: 1136 MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLA 1195
             RG  G  G PG PG  G  G  G +G+ GE G PG  G  G  GP GE GEKG P    
Sbjct: 1322 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381

Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255
               +         + D   +  + P     Q  +PG      PG +    + G  G  G 
Sbjct: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI-----PGHKGHTGLMGPQGLPGE 1436

Query: 1256 HLEGRGEPGAVGQMGSPGQQGAS 1278
            +    G PG  GQ G PG +G S
Sbjct: 1437 N-GPVGPPGPPGQPGFPGLRGES 1458



 Score =  131 bits (329), Expect = 5e-30
 Identities = 94/242 (38%), Positives = 107/242 (44%), Gaps = 44/242 (18%)

Query: 1072 GPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            GP G +G PGLPG     G PGE G  GP GPPG KG++G HG PG  G+PG  G  G  
Sbjct: 868  GPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---- 1184
            G  GP G  G  G  G PG  G RG +G AG  G+ G  GP G  G  GLPGP G+    
Sbjct: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 987

Query: 1185 ----RGEKGEPQSLATLY---------------QLVS--------QASHVSKFDSFHENT 1217
                RG  G P  L T                 Q V           S  S+ D      
Sbjct: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047

Query: 1218 RPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
             PP P       PG +  GSPG+R     PG  G  GR     G PG  G+ G PG+ G 
Sbjct: 1048 GPPGP----SGPPGDK--GSPGSRGLPGFPGPQGPAGRD----GAPGNPGERGPPGKPGL 1097

Query: 1278 ST 1279
            S+
Sbjct: 1098 SS 1099



 Score =  125 bits (315), Expect = 2e-28
 Identities = 86/238 (36%), Positives = 106/238 (44%), Gaps = 32/238 (13%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG---LPGLQGHPGHQGIPG 1126
            T G  G  GPPGLPG  G  G QG  G RG  G  G+KGD G   +PG  G PG+ G PG
Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 1204

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER---------GPPGTVGPTG 1177
              G+ G  G  G++G+ G  GPPGP+G  G+ G  G  G+          G PG  G  G
Sbjct: 1205 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264

Query: 1178 LPGPKGERGEKG-----------EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ 1226
            LPGP+G RG  G            P+  +    L  Q     K D     T P  P   +
Sbjct: 1265 LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK-DGDTGPTGPQGPQGPR 1323

Query: 1227 KLEPGTEPLGSPGTRSKALVPGEWGRGGRH--------LEGRGEPGAVGQMGSPGQQG 1276
                     GSPG    +  PG+ G  G +        L  RG PG  G+ G PG++G
Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381



 Score =  123 bits (309), Expect = 1e-27
 Identities = 88/225 (39%), Positives = 111/225 (49%), Gaps = 45/225 (20%)

Query: 1072 GPPGPQGPPGLPG----RNGTPGEQGFPGPRG------PPGVKGE---KGDHGLPGLQGH 1118
            G  GP GPPG+PG    + G  GEQG PGPRG      PPG +G    +G  G PGLQG 
Sbjct: 635  GDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGL 694

Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178
             G +G  G  G+ G  G++G  G  G+PGPPGP G  G+ G  G  G+ GPPG   PTG 
Sbjct: 695  RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPG---PTGP 751

Query: 1179 P------GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
            P      GP G  G KGEP                       E+  P  P L  ++  G 
Sbjct: 752  PGKDGPNGPPGPPGTKGEPGERG-------------------EDGLPGKPGLRGEI--GE 790

Query: 1233 EPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            + L G PG + +A +PG  G  G   E +G+ G  G++G PG +G
Sbjct: 791  QGLAGRPGEKGEAGLPGAPGFPGVRGE-KGDQGEKGELGLPGLKG 834



 Score =  123 bits (309), Expect = 1e-27
 Identities = 87/263 (33%), Positives = 105/263 (39%), Gaps = 76/263 (28%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGL------PGLQGHPGHQGI 1124
            PG  GP+GPPG PG  G PG++G PG  G PG KGE+GD G+      PG +G PG  GI
Sbjct: 1359 PGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGI 1418

Query: 1125 PGR---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA--------------------- 1160
            PG     GL GP+G+ G  G  G PGPPG  GF G+ G                      
Sbjct: 1419 PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLET 1478

Query: 1161 --------------RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASH 1206
                          + + G  GPPG  G  GLPG  G  GE G P               
Sbjct: 1479 RLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ------------- 1525

Query: 1207 VSKFDSFHENTRPPMPILEQ--KLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG----- 1259
                      + P  P  E+  K +PG   +G  G      +PG+ G  G   +G     
Sbjct: 1526 ----GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1581

Query: 1260 --------RGEPGAVGQMGSPGQ 1274
                     G PG  G  G PGQ
Sbjct: 1582 GPQGETGPAGHPGLPGPPGPPGQ 1604



 Score =  123 bits (308), Expect = 1e-27
 Identities = 84/224 (37%), Positives = 100/224 (44%), Gaps = 58/224 (25%)

Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPGHQGIPG 1126
            PPGP G PGLPG  G  G  G PG  G  G KGE G  GLPG       QG  G +G  G
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA------RGTSGERGPPGTVGPTGLPG 1180
             VG +G +G  G+ G  G PG PGP G  G+AGA      +G+ G+ GPPG  GP+GLPG
Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237

Query: 1181 PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGT 1240
              GE G++G                                       +PG  P G PG 
Sbjct: 1238 IPGEEGKEGRDG------------------------------------KPG--PPGEPGK 1259

Query: 1241 RSKALVPGEWGRGG-----RHLEGRGEPGAVGQ---MGSPGQQG 1276
              +  +PG  G  G      H    G PG  G+   MG PGQ+G
Sbjct: 1260 AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303



 Score =  122 bits (306), Expect = 2e-27
 Identities = 88/245 (35%), Positives = 103/245 (42%), Gaps = 50/245 (20%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV----------------KGEKGDHGLPGL 1115
            G  G +G  GLPG  G  GE+G  GP GPPG+                +G KG+ G PGL
Sbjct: 819  GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 878

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
             G PG QG PG +G QGP G  G +G  G  G PG  G  G  G  G  G  GPPG+VG 
Sbjct: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938

Query: 1176 TGL---PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             GL   PG  GERGEKG             +           +   P +P       PG 
Sbjct: 939  PGLRGTPGKDGERGEKG----------AAGEEGSPGPVGPRGDPGAPGLP-----GPPGK 983

Query: 1233 EPLGSPGTRSKALVPGEWGR---------------GGRHLEG-RGEPGAVGQMGSPGQQG 1276
               G PG R    +PG  G                GG+ ++G RG PG  G  GS G  G
Sbjct: 984  GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG 1043

Query: 1277 ASTQG 1281
                G
Sbjct: 1044 IGVAG 1048



 Score =  119 bits (298), Expect = 2e-26
 Identities = 92/268 (34%), Positives = 114/268 (42%), Gaps = 49/268 (18%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGL-----PGRNGTPGEQGFPGPRGPPGV 1103
            R  E C             PG PG    +G PG+     PG +G PG++G PG RG PG 
Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGF 1070

Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQG------------------PKGMRGLEGTAGL 1145
             G +G  G  G  G+PG +G PG+ GL                    P G  GL G  G 
Sbjct: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF 1130

Query: 1146 PGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQA- 1204
             G  G  G  G  G  G  GE GPPG  GP G+ GP+G +GE+G    +    Q   Q  
Sbjct: 1131 KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG---QKGDQGH 1187

Query: 1205 SHVSKFDSFHENTRPP----------MPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRG 1253
              V  F     N  PP           P ++    PG E P G  G      +PGE G+ 
Sbjct: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQG--SPGKEGPPGPQGPSGLPGIPGEEGKE 1245

Query: 1254 GRHLEGR----GEPGAVGQMGSPGQQGA 1277
            GR  +G+    GEPG  G+ G PG +GA
Sbjct: 1246 GR--DGKPGPPGEPGKAGEPGLPGPEGA 1271



 Score =  112 bits (281), Expect = 2e-24
 Identities = 89/265 (33%), Positives = 108/265 (40%), Gaps = 98/265 (36%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGE--QGFPGPRGPPGVKGE--------------------- 1106
            +PGP GP+G PG PG  G PG+   G PG RG PG+ G                      
Sbjct: 962  SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021

Query: 1107 --KGDHGLPGLQGHPGHQGIPG-----RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159
              KGD G PG+ G PG +G PG       G  GP G +G  G+ GLPG PGP+G  G  G
Sbjct: 1022 CVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081

Query: 1160 ARGTSGERGPPGTVG------------------------PTGLPGPKGERGEKGEPQSLA 1195
            A G  GERGPPG  G                        P GLPG  G +G+KG P    
Sbjct: 1082 APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG--- 1138

Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255
                                             +PG E  G+ G + +A  PG  G  G 
Sbjct: 1139 ---------------------------------KPGRE--GTEGKKGEAGPPGLPGPPG- 1162

Query: 1256 HLEG----RGEPGAVGQMGSPGQQG 1276
             + G    +GE GA G++G  G QG
Sbjct: 1163 -IAGPQGSQGERGADGEVGQKGDQG 1186



 Score =  112 bits (280), Expect = 2e-24
 Identities = 96/284 (33%), Positives = 114/284 (40%), Gaps = 63/284 (22%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPP---GLPGRNGTPGEQGFPGPRGPPGVKGEKGDH 1110
            G T P        +   PG  G  G P   G PG +G PG  G PG RG PG  GE+G+ 
Sbjct: 895  GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 954

Query: 1111 GLPGLQGHP---GHQGIPGRVGLQGPKGM-----RGLEGTAGLPGPPGP----------- 1151
            G  G +G P   G +G PG  GL GP G       GL G+ GLPGP G            
Sbjct: 955  GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014

Query: 1152 ---------RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQS--LATLYQL 1200
                     +G +G  G  G+ G RG PG +G  G PGP G  G+KG P S  L      
Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073

Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-----------------GSPGTRSK 1243
               A       +  E   P  P L   L PG   L                 G PG +  
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133

Query: 1244 ALVPGEWGRGGRHLEGR----------GEPGAVGQMGSPGQQGA 1277
              VPG+ GR G   EG+          G PG  G  GS G++GA
Sbjct: 1134 KGVPGKPGREG--TEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 59/130 (45%), Positives = 67/130 (51%), Gaps = 21/130 (16%)

Query: 1058 PAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKG 1108
            PA++ +   S   PGPPGP G  GLPGR G  GE G PG         P GP G +G KG
Sbjct: 1489 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545

Query: 1109 DHGLPG--LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE 1166
            D G PG  L+G  G  GIPG+ G  G           GLPG PGP+G  G AG  G  G 
Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPG-------YAKDGLPGIPGPQGETGPAGHPGLPGP 1598

Query: 1167 RGPPGTVGPT 1176
             GPPG   P+
Sbjct: 1599 PGPPGQCDPS 1608


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score =  159 bits (402), Expect = 2e-38
 Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286

Query: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342

Query: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402

Query: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461

Query: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520

Query: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T  PA
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634



 Score =  148 bits (373), Expect = 4e-35
 Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425
            P +   +  +P PT L  + +   ++R++W P P   L   +V  +         E+ + 
Sbjct: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317

Query: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
                +  L NL   TEY+VSV  +YE      LRG   T  L  P  +  + +T  +  +
Sbjct: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376

Query: 486  TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
             W  P A  T Y +R  P    G   E  V   R  + L  L PG +Y VS+ +L G E 
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 545  SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603
            S    I  ++     PR L     +  +  + W+     VR  R+TY    GG+S   E 
Sbjct: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494

Query: 604  -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659
              PG+ ++AT+  L     YT+ V  +   G S   +  ++     +   PSQ+ +T++ 
Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             +++ + W+ ++ S V  Y++T TP  G G     +   +     + GL    EY V++ 
Sbjct: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777
            A    G  S P+      + V+  P P++L     TP SL   WTPP  ++  Y +   P
Sbjct: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668

Query: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814
                GP K +++    S V +  L  ATKY V V A+
Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705



 Score =  145 bits (367), Expect = 2e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130

Query: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187

Query: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304

Query: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362

Query: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421

Query: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531



 Score =  127 bits (320), Expect = 5e-29
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395

Query: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443



 Score =  115 bits (288), Expect = 3e-25
 Identities = 119/490 (24%), Positives = 213/490 (43%), Gaps = 26/490 (5%)

Query: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437
            P  L +   T +S+ +SW  AP   ++Y  +     GG    +E  V G  ++  +  L 
Sbjct: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509

Query: 438  SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493
               +Y ++V+ +   G        ++      +  P  + +  V   ++ + W PS+   
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553
            T Y V  +P +  G  + +     + E+ ++GL+P  +Y VSV + + P G     ++  
Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628

Query: 554  TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609
              T+  P  L F+ V+  +    W   P  V+L    VRVT     G       AP +++
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685

Query: 610  SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668
            S  +  L  +T Y V V  L     S    G VTT +  SP + + +T+     + ++W 
Sbjct: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745

Query: 669  AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728
                + +  +Q+   P       + ++  ++ +  + GL   T+Y + +     D ARS 
Sbjct: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803

Query: 729  PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788
            PV +    ++ +   PSNL   + TP+SL VSW PP  R+  Y + Y    G  P + V 
Sbjct: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859

Query: 789  VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT-ACPAL--RPDGSLPGFD 844
             P    +  T+  L+  T+Y + V A+    +SE +    +T   P L   P  +L G +
Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919

Query: 845  LMVAFSLVEK 854
            ++   S V+K
Sbjct: 1920 ILDVPSTVQK 1929



 Score =  104 bits (259), Expect = 6e-22
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 112/484 (23%), Positives = 182/484 (37%), Gaps = 42/484 (8%)

Query: 360  QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418
            Q  S    P    A+ T+PAPT L  +QVT +S+   WTP       Y + V    + G 
Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674

Query: 419  PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477
             +E+ +   ++S  +  L   T+Y VSV+ + +       +G+VTT   + PPR   +  
Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734

Query: 478  VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
             T  T+ ++W+      T + V   PA+ +    +R ++       + GL+PG DY++ +
Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596
             +L     S    I A T  +  P +L F   + ++  V W+  P   R+        + 
Sbjct: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850

Query: 597  GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653
            G   +   P      T AT+  L   T YT+ V  L     S  L GR  T + P     
Sbjct: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP----- 1905

Query: 654  SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEY 713
             +  LP   +    +   PS V        P G    + I +PG  G    P +G+   +
Sbjct: 1906 QLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-GYDTGNGIQLPGTSGQQ--PSVGQQMIF 1962

Query: 714  DVTILAYYRDGARSDPVSLR---YTPST-----VSRSPPS---------------NLALA 750
            +            + P+  R   Y P+      +   P                 N +  
Sbjct: 1963 EEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTG 2022

Query: 751  SETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVL 810
             E      +SW  P      Y ++  P           VPG  +  TL  L     Y ++
Sbjct: 2023 QEALSQTTISWA-PFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2081

Query: 811  VSAI 814
            V A+
Sbjct: 2082 VEAL 2085



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 15/64 (23%), Positives = 27/64 (42%)

Query: 485  LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
            ++W P    + Y++ C P     E  +  V        L GL  G  Y + V++L+  + 
Sbjct: 2031 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2090

Query: 545  SEAR 548
             + R
Sbjct: 2091 HKVR 2094


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score =  159 bits (402), Expect = 2e-38
 Identities = 149/537 (27%), Positives = 234/537 (43%), Gaps = 31/537 (5%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286

Query: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342

Query: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402

Query: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461

Query: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520

Query: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T  PA
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPA 1634



 Score =  148 bits (373), Expect = 4e-35
 Identities = 125/457 (27%), Positives = 200/457 (43%), Gaps = 19/457 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRA--SRGGTPREVVVE 425
            P +   +  +P PT L  + +   ++R++W P P   L   +V  +         E+ + 
Sbjct: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317

Query: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
                +  L NL   TEY+VSV  +YE      LRG   T  L  P  +  + +T  +  +
Sbjct: 1318 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTV 1376

Query: 486  TW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
             W  P A  T Y +R  P    G   E  V   R  + L  L PG +Y VS+ +L G E 
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 545  SEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTE- 603
            S    I  ++     PR L     +  +  + W+     VR  R+TY    GG+S   E 
Sbjct: 1437 SPLL-IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY-GETGGNSPVQEF 1494

Query: 604  -APGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTK---KAPSPSQLSMTELP 659
              PG+ ++AT+  L     YT+ V  +   G S   +  ++     +   PSQ+ +T++ 
Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             +++ + W+ ++ S V  Y++T TP  G G     +   +     + GL    EY V++ 
Sbjct: 1555 DNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1613

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSP-PSNLALASETPDSLQVSWTPPLGRVLHYWLTYAP 777
            A    G  S P+      + V+  P P++L     TP SL   WTPP  ++  Y +   P
Sbjct: 1614 AQNPSG-ESQPL----VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTP 1668

Query: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAI 814
                GP K +++    S V +  L  ATKY V V A+
Sbjct: 1669 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1705



 Score =  145 bits (367), Expect = 2e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130

Query: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187

Query: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304

Query: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362

Query: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421

Query: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531



 Score =  127 bits (320), Expect = 5e-29
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395

Query: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443



 Score =  115 bits (289), Expect = 2e-25
 Identities = 113/467 (24%), Positives = 202/467 (43%), Gaps = 23/467 (4%)

Query: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTP--REVVVEGPAASTELHNLA 437
            P  L +   T +S+ +SW  AP   ++Y  +     GG    +E  V G  ++  +  L 
Sbjct: 1451 PRDLEVVAATPTSLLISWD-APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509

Query: 438  SRTEYLVSVFPIYEGGVGEGLRGLVTT---APLPPPRALTLAAVTPRTVHLTWQPSAG-A 493
               +Y ++V+ +   G        ++      +  P  + +  V   ++ + W PS+   
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRAR 553
            T Y V  +P +  G  + +     + E+ ++GL+P  +Y VSV + + P G     ++  
Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA-QNPSGESQPLVQTA 1628

Query: 554  TPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL----VRVTYVSSEGGHSGQTEAPGNAT 609
              T+  P  L F+ V+  +    W   P  V+L    VRVT     G       AP +++
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQW--TPPNVQLTGYRVRVTPKEKTGPMKEINLAP-DSS 1685

Query: 610  SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLS-MTELPGDAVQLAWV 668
            S  +  L  +T Y V V  L     S    G VTT +  SP + + +T+     + ++W 
Sbjct: 1686 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745

Query: 669  AAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSD 728
                + +  +Q+   P       + ++  ++ +  + GL   T+Y + +     D ARS 
Sbjct: 1746 TKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNARSS 1803

Query: 729  PVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVS 788
            PV +    ++ +   PSNL   + TP+SL VSW PP  R+  Y + Y    G  P + V 
Sbjct: 1804 PVVI---DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY-EKPGSPPREVVP 1859

Query: 789  VP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPAL 834
             P    +  T+  L+  T+Y + V A+    +SE +    +T   AL
Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEAL 1906



 Score =  104 bits (259), Expect = 6e-22
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 94.7 bits (234), Expect = 5e-19
 Identities = 96/367 (26%), Positives = 155/367 (42%), Gaps = 24/367 (6%)

Query: 360  QGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGT 418
            Q  S    P    A+ T+PAPT L  +QVT +S+   WTP       Y + V    + G 
Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674

Query: 419  PREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAP-LPPPRALTLAA 477
             +E+ +   ++S  +  L   T+Y VSV+ + +       +G+VTT   + PPR   +  
Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734

Query: 478  VTPRTVHLTWQPSAGA-THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
             T  T+ ++W+      T + V   PA+ +    +R ++       + GL+PG DY++ +
Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1793

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEG 596
             +L     S    I A T  +  P +L F   + ++  V W+  P   R+        + 
Sbjct: 1794 YTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQ--PPRARITGYIIKYEKP 1850

Query: 597  GHSGQTEAP---GNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQL 653
            G   +   P      T AT+  L   T YT+ V  L     S  L GR    K      L
Sbjct: 1851 GSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR----KKTGQEAL 1906

Query: 654  SMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTE 712
            S T        ++W  A       Y I+  P+G + +  +  VPG   +A L GL R   
Sbjct: 1907 SQT-------TISW--APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 1957

Query: 713  YDVTILA 719
            Y++ + A
Sbjct: 1958 YNIIVEA 1964



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 111/525 (21%), Positives = 185/525 (35%), Gaps = 87/525 (16%)

Query: 69   QEVILTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARR--------------EFVIE 114
            QE  +      AT+ GL P   YT+ ++ +TG G    + +              +  + 
Sbjct: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1551

Query: 115  DLKSSSLD----RSSQRPLG-------SGAPEPTPSHTGSPDPEQAS----EPQVAFTPS 159
            D++ +S+      SS    G          P PT + T  PD  + +    +P V +  S
Sbjct: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611

Query: 160  QDPRTPAGPQFRCLP------PVPADMVFL------VDGSWSIGHSHFQQVKDFLASVIA 207
               + P+G     +       P P D+ F       +   W+  +    Q+  +   V  
Sbjct: 1612 VYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNV---QLTGYRVRVTP 1668

Query: 208  PFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLG 267
              + GP K ++ L   S        +  ++TK +V        Y   +T T      V+ 
Sbjct: 1669 KEKTGPMK-EINLAPDSSSVVVSGLM--VATKYEVSV------YALKDTLTSRPAQGVVT 1719

Query: 268  --QNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRL 325
              +N+ P    R   A    +    +++ +  T        G  V AV   N      R 
Sbjct: 1720 TLENVSPPRRARVTDATETTITISWRTKTETIT--------GFQVDAVPA-NGQTPIQRT 1770

Query: 326  LASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVL 385
            +    R  T+         G   G   ++    L   + R  P    A   + AP++L  
Sbjct: 1771 IKPDVRSYTI--------TGLQPGTDYKIYLYTLNDNA-RSSPVVIDASTAIDAPSNLRF 1821

Query: 386  SQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTE--LHNLASRTEYL 443
               T +S+ +SW P PR  +   I+     G  PREVV       TE  +  L   TEY 
Sbjct: 1822 LATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 1880

Query: 444  VSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPA 503
            + V  +      E L G   T            A++  T+  +W P    + Y++ C P 
Sbjct: 1881 IYVIALKNNQKSEPLIGRKKTGQ---------EALSQTTI--SWAPFQDTSEYIISCHPV 1929

Query: 504  SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548
                E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 1930 GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 1974


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score =  155 bits (392), Expect = 2e-37
 Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286

Query: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342

Query: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402

Query: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461

Query: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520

Query: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630



 Score =  146 bits (369), Expect = 1e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416

Query: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535

Query: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594

Query: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652

Query: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709

Query: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766

Query: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
             +++    S V +  L  ATKY V V A+
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795



 Score =  145 bits (367), Expect = 2e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130

Query: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187

Query: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304

Query: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362

Query: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421

Query: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531



 Score =  127 bits (320), Expect = 5e-29
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395

Query: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443



 Score =  114 bits (286), Expect = 5e-25
 Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%)

Query: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642

Query: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693

Query: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750

Query: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809

Query: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868

Query: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924

Query: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983

Query: 822  AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854
             +    +T   P L   P  +L G +++   S V+K
Sbjct: 1984 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2019



 Score =  104 bits (259), Expect = 6e-22
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 34.3 bits (77), Expect = 0.79
 Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query: 466  PLPPPRALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDG 525
            P P P  +   A++  T+  +W P    + Y++ C P     E  +  V        L G
Sbjct: 2073 PRPYPPNVGQEALSQTTI--SWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 2130

Query: 526  LEPGRDYEVSVQSLRGPEGSEAR 548
            L  G  Y + V++L+  +  + R
Sbjct: 2131 LTRGATYNIIVEALKDQQRHKVR 2153


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score =  155 bits (392), Expect = 2e-37
 Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286

Query: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342

Query: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402

Query: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461

Query: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520

Query: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630



 Score =  146 bits (369), Expect = 1e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416

Query: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535

Query: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594

Query: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652

Query: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709

Query: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766

Query: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
             +++    S V +  L  ATKY V V A+
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795



 Score =  145 bits (367), Expect = 2e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130

Query: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187

Query: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247

Query: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304

Query: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362

Query: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421

Query: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531



 Score =  127 bits (320), Expect = 5e-29
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395

Query: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443



 Score =  115 bits (287), Expect = 4e-25
 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%)

Query: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642

Query: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693

Query: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750

Query: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809

Query: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868

Query: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924

Query: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983

Query: 822  AVSATGQTACPALRPDGSLPGFD 844
             +   G+       P  + PG+D
Sbjct: 1984 PL--IGRKKTVQKTPFVTHPGYD 2004



 Score =  104 bits (259), Expect = 6e-22
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424
            R  P    A   + AP++L     T +S+ +SW P PR  +   I+     G  PREVV 
Sbjct: 1891 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 1949

Query: 425  EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456
                  TE  +  L   TEY + V                           P Y+ G G 
Sbjct: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009

Query: 457  GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489
             L G     P                 PP   T     PR               ++W P
Sbjct: 2010 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069

Query: 490  SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548
                + Y++ C P     E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 2070 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2128


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score =  152 bits (383), Expect = 3e-36
 Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425
            P +   +  +P  T L    +T SSI L WTP     +  Y I   A+  G P  E  V+
Sbjct: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317

Query: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
                   +  L    +Y +SV  +  GG          TA +PPP  L    + P T+ +
Sbjct: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376

Query: 486  TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541
            TW P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+  
Sbjct: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433

Query: 542  PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599
             E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G  
Sbjct: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +    
Sbjct: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
              ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ 
Sbjct: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610

Query: 719  AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
            A    G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T 
Sbjct: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667

Query: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721



 Score =  146 bits (369), Expect = 1e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507

Query: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626

Query: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685

Query: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743

Query: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800

Query: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857

Query: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
             +++    S V +  L  ATKY V V A+
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886



 Score =  136 bits (343), Expect = 1e-31
 Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +   + P  + LS  ++ 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
              ++ L W     S ++ Y+IT    GEG    E  V  ++G   + GL    +YD++++
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777
                +G  S P +L    +     PP++L   +  PD+++V+W PP    + ++ + Y+P
Sbjct: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395

Query: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
                     +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447



 Score =  133 bits (335), Expect = 1e-30
 Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +    +P    L+   +T  ++ L 
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286

Query: 487  WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541
            W P   +T    R +  +  GE     E+  +  VG   V   GLEPG DY++SV +L  
Sbjct: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343

Query: 542  PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596
              G  A     +   + PP  L F+++  D  RV W  AP P       LVR + V +E 
Sbjct: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400

Query: 597  GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656
              +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+ +  +
Sbjct: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458

Query: 657  ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            ++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   TEY V
Sbjct: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
            +I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +Y +TY
Sbjct: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573

Query: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
                G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622



 Score =  114 bits (286), Expect = 5e-25
 Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%)

Query: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674

Query: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733

Query: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784

Query: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841

Query: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900

Query: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959

Query: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015

Query: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074

Query: 822  AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854
             +    +T   P L   P  +L G +++   S V+K
Sbjct: 2075 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2110



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774
            ++    +D   S P+S    P        ++L+    T  S+ + WTP     ++ Y +T
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832
               A    P     V  +  + T+  L+    Y + V  +   G S   + T QTA P
Sbjct: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 15/64 (23%), Positives = 27/64 (42%)

Query: 485  LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
            ++W P    + Y++ C P     E  +  V        L GL  G  Y + V++L+  + 
Sbjct: 2212 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271

Query: 545  SEAR 548
             + R
Sbjct: 2272 HKVR 2275


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score =  152 bits (383), Expect = 3e-36
 Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425
            P +   +  +P  T L    +T SSI L WTP     +  Y I   A+  G P  E  V+
Sbjct: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317

Query: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
                   +  L    +Y +SV  +  GG          TA +PPP  L    + P T+ +
Sbjct: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376

Query: 486  TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541
            TW P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+  
Sbjct: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433

Query: 542  PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599
             E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G  
Sbjct: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +    
Sbjct: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
              ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ 
Sbjct: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610

Query: 719  AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
            A    G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T 
Sbjct: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667

Query: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
             P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721



 Score =  146 bits (369), Expect = 1e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507

Query: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566

Query: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626

Query: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685

Query: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743

Query: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800

Query: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857

Query: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
             +++    S V +  L  ATKY V V A+
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886



 Score =  136 bits (343), Expect = 1e-31
 Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%)

Query: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047

Query: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103

Query: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160

Query: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
             +     + +S T   LS    Y V V  +     S  ++  +   + P  + LS  ++ 
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279

Query: 660  GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
              ++ L W     S ++ Y+IT    GEG    E  V  ++G   + GL    +YD++++
Sbjct: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339

Query: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777
                +G  S P +L    +     PP++L   +  PD+++V+W PP    + ++ + Y+P
Sbjct: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395

Query: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
                     +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447



 Score =  133 bits (335), Expect = 1e-30
 Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%)

Query: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227

Query: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
              +S    NL+   EY VSV+ + +      +   +    +P    L+   +T  ++ L 
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286

Query: 487  WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541
            W P   +T    R +  +  GE     E+  +  VG   V   GLEPG DY++SV +L  
Sbjct: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343

Query: 542  PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596
              G  A     +   + PP  L F+++  D  RV W  AP P       LVR + V +E 
Sbjct: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400

Query: 597  GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656
              +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+ +  +
Sbjct: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458

Query: 657  ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            ++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   TEY V
Sbjct: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
            +I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +Y +TY
Sbjct: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573

Query: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
                G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622



 Score =  115 bits (287), Expect = 4e-25
 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%)

Query: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674

Query: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733

Query: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784

Query: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841

Query: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900

Query: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959

Query: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015

Query: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074

Query: 822  AVSATGQTACPALRPDGSLPGFD 844
             +   G+       P  + PG+D
Sbjct: 2075 PL--IGRKKTVQKTPFVTHPGYD 2095



 Score =  102 bits (255), Expect = 2e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648

Query: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826

Query: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886

Query: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945

Query: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001

Query: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060

Query: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098



 Score = 91.3 bits (225), Expect = 5e-18
 Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954

Query: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013

Query: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072

Query: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127

Query: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185

Query: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245

Query: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774
            ++    +D   S P+S    P        ++L+    T  S+ + WTP     ++ Y +T
Sbjct: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301

Query: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832
               A    P     V  +  + T+  L+    Y + V  +   G S   + T QTA P
Sbjct: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359



 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648

Query: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708

Query: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768

Query: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828

Query: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886

Query: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945

Query: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663

Query: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723

Query: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783

Query: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842

Query: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%)

Query: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424
            R  P    A   + AP++L     T +S+ +SW P PR  +   I+     G  PREVV 
Sbjct: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 2040

Query: 425  EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456
                  TE  +  L   TEY + V                           P Y+ G G 
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2100

Query: 457  GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489
             L G     P                 PP   T     PR               ++W P
Sbjct: 2101 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2160

Query: 490  SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548
                + Y++ C P     E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 2161 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2219


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  144 bits (363), Expect = 5e-34
 Identities = 95/231 (41%), Positives = 115/231 (49%), Gaps = 41/231 (17%)

Query: 1072 GPPGPQGPPGLPG------------RNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP 1119
            GP G +GP GLPG              G PG  GFPGP+GP G  G+ GD G  GL G  
Sbjct: 460  GPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGAR 519

Query: 1120 GHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---GTVGPT 1176
            G  G  G  G QGP G +G++G  G  GPPGP GFQG+ G  G +GE G P   G  G  
Sbjct: 520  GAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEF 579

Query: 1177 GLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG----- 1231
            GLPGP G RGE+G P          S A+  +        + PP P    K EPG     
Sbjct: 580  GLPGPAGPRGERGPPGE--------SGAAGPTGPIGSRGPSGPPGPD-GNKGEPGVVGAV 630

Query: 1232 -----TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 + P G PG R  A +PG  G+G      +GEPG  G++G+PG+ GA
Sbjct: 631  GTAGPSGPSGLPGERGAAGIPG--GKG-----EKGEPGLRGEIGNPGRDGA 674



 Score =  134 bits (336), Expect = 7e-31
 Identities = 94/258 (36%), Positives = 110/258 (42%), Gaps = 36/258 (13%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPG---RNGTPGEQGFPGPRGPPGVKGEKGDH 1110
            GE  PA     S +   PG  GPQGPPG  G   + G  GE G  GP GPPG++G  G  
Sbjct: 346  GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSR 405

Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP---GPRGFQGMAGARGTSGER 1167
            GLPG  G  G  G PG  G  GP G+RG  G AG PG P   GPRG  G  G  G +G+ 
Sbjct: 406  GLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE 465

Query: 1168 GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR--------- 1218
            GP G  G  G PGP G  G +GEP ++                D  H             
Sbjct: 466  GPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525

Query: 1219 -------PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG-------RHLEGR---- 1260
                   PP P   Q ++ G    G PG      +PG  G  G       R L G     
Sbjct: 526  GNNGAQGPPGP---QGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLP 582

Query: 1261 GEPGAVGQMGSPGQQGAS 1278
            G  G  G+ G PG+ GA+
Sbjct: 583  GPAGPRGERGPPGESGAA 600



 Score =  133 bits (335), Expect = 1e-30
 Identities = 90/206 (43%), Positives = 97/206 (47%), Gaps = 20/206 (9%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP G  GPPG PG  G  GE G  G  GP G  G +G+ GLPGL G  G  G PG  GL 
Sbjct: 247  GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G KG  GL G AG PG PGPRG  G  GA G +G RG  G  GP G    KGE G KGEP
Sbjct: 307  GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG---SKGESGNKGEP 363

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEW 1250
                      S         S  E  R P         PG   L GSPG+R    +PG  
Sbjct: 364  G---------SAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRG---LPGAD 411

Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            GR G      G PG+ G  G  G +G
Sbjct: 412  GRAG----VMGPPGSRGASGPAGVRG 433



 Score =  122 bits (307), Expect = 2e-27
 Identities = 96/273 (35%), Positives = 111/273 (40%), Gaps = 61/273 (22%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL-------------------------- 1082
            P  RDGE  P         +  PGPPGP GPPGL                          
Sbjct: 49   PPGRDGEDGP---------TGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR 99

Query: 1083 --PGRNGTPGEQGFPGPRGPPG---------VKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
              PG  G PG QGF GP G PG          +G  G  G  G  GHPG  G PG  G+ 
Sbjct: 100  GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV 159

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR---GTSGERGPPGTVGPTGLPGPKGERGEK 1188
            GP+G RG  GT GLPG  G RG  G+ G +   G  G +G PG  G  G PG  G RG  
Sbjct: 160  GPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLP 219

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            GE   +       ++ S     D       P  PI      PG    G+PG + +    G
Sbjct: 220  GERGRVGAPGPAGARGS-----DGSVGPVGPAGPI-GSAGPPGFP--GAPGPKGEIGAVG 271

Query: 1249 EWGRGGRHLEGRGE---PGAVGQMGSPGQQGAS 1278
              G  G     RGE   PG  G +G PG  GA+
Sbjct: 272  NAGPAG-PAGPRGEVGLPGLSGPVGPPGNPGAN 303



 Score =  120 bits (302), Expect = 6e-27
 Identities = 90/253 (35%), Positives = 104/253 (41%), Gaps = 55/253 (21%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPG---EQGFPGPRGPPGVKG 1105
            PA   GE  P   S  +  +   G  GP GPPG  G  G PG     G  GP GP G+ G
Sbjct: 584  PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPG 643

Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA----- 1160
            E+G  G+PG +G  G  G+ G +G  G  G RG  G  G PGP G  G +G AGA     
Sbjct: 644  ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703

Query: 1161 ----RGTSGERGPPGTVGPTGL---------PGPKGERGEKGEPQSLATLYQLVSQASHV 1207
                RG+ GERG  G  GP G          PG KGERG KG                  
Sbjct: 704  PAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKG------------------ 745

Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGA 1265
                          P  E  +   T P+G+ G       PG  G RG     G  G PGA
Sbjct: 746  --------------PKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGA 791

Query: 1266 VGQMGSPGQQGAS 1278
             G+ G PG  G S
Sbjct: 792  AGRTGPPGPSGIS 804



 Score =  120 bits (301), Expect = 8e-27
 Identities = 93/288 (32%), Positives = 116/288 (40%), Gaps = 59/288 (20%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPR---------- 1098
            PA   G+  P  ++    ++   GPPGP G  G PG  G  G++G  GPR          
Sbjct: 773  PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832

Query: 1099 -----GPPGVKGEKGDHGLPGLQGHPGHQ------GIPGRVGLQGPKGMRGLEGTAGLPG 1147
                 GPPG  GEKG  G  G  G PG        G PG +GL G +G RGL G AG  G
Sbjct: 833  EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892

Query: 1148 PPGPRGFQGMAGAR---------------GTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192
             PGP G  G  GAR               G +G  G PG  GP G  G  G +GE+G P 
Sbjct: 893  EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952

Query: 1193 SLATLYQLVSQASHVSKFDSFHENTR---------------------PPMPILEQKLEPG 1231
            ++  +    +   H     +     R                      P  I   K EPG
Sbjct: 953  NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012

Query: 1232 TE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
             + P G PG +    + G  G  G H + +G PG+VG  G  G  G S
Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGD-QGAPGSVGPAGPRGPAGPS 1059



 Score =  120 bits (301), Expect = 8e-27
 Identities = 61/115 (53%), Positives = 67/115 (58%), Gaps = 3/115 (2%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP GP GP G+ G  G PGE+G   PRG PG+KG  G  GLPG+ GH G QG PG VG  
Sbjct: 994  GPRGPSGPQGIRGDKGEPGEKG---PRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPA 1050

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
            GP+G  G  G AG  G  G  G  G AG RG  G +GP G  GP G PGP G  G
Sbjct: 1051 GPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score =  119 bits (299), Expect = 1e-26
 Identities = 86/229 (37%), Positives = 98/229 (42%), Gaps = 20/229 (8%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ---GFPGPRGPPGVKGEKGDH 1110
            G+T PA     +      G  G  G PG PG  G  G Q   GFPG  G PG KG +G +
Sbjct: 124  GQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHN 183

Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170
            GL GL+G PG  G+ G  G  G  G  G  G  GLPG  G  G  G AGARG+ G  GP 
Sbjct: 184  GLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPV 243

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230
            G  GP G  GP G  G  G    +      V  A              P  P  E  L  
Sbjct: 244  GPAGPIGSAGPPGFPGAPGPKGEIGA----VGNAGPAG----------PAGPRGEVGLPG 289

Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278
             + P+G PG      + G  G  G  L G  G PG  G  G PG  GA+
Sbjct: 290  LSGPVGPPGNPGANGLTGAKGAAG--LPGVAGAPGLPGPRGIPGPVGAA 336



 Score =  119 bits (297), Expect = 2e-26
 Identities = 82/213 (38%), Positives = 102/213 (47%), Gaps = 28/213 (13%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G  GP G  G +G  GE G  GP+GPPG  GE+G  G  G  G  G  G PG  G  
Sbjct: 343  GLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSP 402

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPTGLPGPKGERGEK 1188
            G +G+ G +G AG+ GPPG RG  G AG RG +G+    G PG +GP GLPG  G  G  
Sbjct: 403  GSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA 462

Query: 1189 GE--PQSLATLYQLVSQASHVSKFDSFHENTRP-PMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G+  P  L  +                  + RP P+     + EPG   +G PG +    
Sbjct: 463  GKEGPVGLPGI------------------DGRPGPIGPAGARGEPGN--IGFPGPKGPTG 502

Query: 1246 VPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
             PG+ G +G   L G RG PG  G  G+ G  G
Sbjct: 503  DPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPG 535



 Score =  118 bits (295), Expect = 4e-26
 Identities = 82/211 (38%), Positives = 101/211 (47%), Gaps = 21/211 (9%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL- 1130
            GP G +GPPG PGR+G  G  G PGP GPPG          PGL G+   Q     VGL 
Sbjct: 39   GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGP---------PGLGGNFAAQYDGKGVGLG 89

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             GP G+ G  G  G  G PGP+GFQG AG  G  G+ GP G  GP G PG  GE G  G+
Sbjct: 90   PGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGK 149

Query: 1191 PQSLATLYQLVSQASH----VSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246
            P        +  Q +           F +  R    +   K +P     G+PG + +   
Sbjct: 150  PGRPGERGVVGPQGARGFPGTPGLPGF-KGIRGHNGLDGLKGQP-----GAPGVKGEPGA 203

Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            PGE G  G+    RG PG  G++G+PG  GA
Sbjct: 204  PGENGTPGQ-TGARGLPGERGRVGAPGPAGA 233



 Score =  117 bits (293), Expect = 7e-26
 Identities = 77/208 (37%), Positives = 87/208 (41%), Gaps = 30/208 (14%)

Query: 1072 GPPGPQGPPGLPGRNGTPG---EQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            GP G  G PG  G  G  G   E G  GP GP G  G  G +G PG  G  G  G PG  
Sbjct: 727  GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G  G  G  G  G +G+ GPPGP G  G  G RG  G++GP G  G  G  GP G  GEK
Sbjct: 787  GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEK 846

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            G      T                      PP     Q L      LG PG+R +  +PG
Sbjct: 847  GPSGEAGT--------------------AGPPGTPGPQGLLGAPGILGLPGSRGERGLPG 886

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G         GEPG +G  G PG +G
Sbjct: 887  VAG-------AVGEPGPLGIAGPPGARG 907



 Score =  114 bits (285), Expect = 6e-25
 Identities = 81/208 (38%), Positives = 99/208 (47%), Gaps = 21/208 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  GP GP G PG  G+ G+ G PG  G PG  G  G  G  G+ G PG  G  G+ GL+
Sbjct: 760  GAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLR 819

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL---PGPKGERGEK 1188
            GP+G +G  G  G  G  GP GF G  G  G +G  GPPGT GP GL   PG  G  G +
Sbjct: 820  GPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSR 879

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            GE + L  +   V +   +           PP      +  PG   +GSPG       PG
Sbjct: 880  GE-RGLPGVAGAVGEPGPLG-------IAGPP----GARGPPGA--VGSPGVNG---APG 922

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            E GR G +    G PG  GQ G  G++G
Sbjct: 923  EAGRDG-NPGNDGPPGRDGQPGHKGERG 949



 Score =  114 bits (285), Expect = 6e-25
 Identities = 80/215 (37%), Positives = 97/215 (45%), Gaps = 22/215 (10%)

Query: 997  GEMGSPPAAGFV----TLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASR 1052
            GE G P  AG V     LG +A   G R    A     +     +   D +   + P  R
Sbjct: 880  GERGLPGVAGAVGEPGPLG-IAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938

Query: 1053 DGET-------CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQG------FPGPRG 1099
            DG+         P  +     +   PGP GP GP G  G  G  G  G        GPRG
Sbjct: 939  DGQPGHKGERGYPGNIGPVGAAG-APGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRG 997

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPG---PPGPRGFQG 1156
            P G +G +GD G PG +G  G  G+ G  GLQG  G+ G  G  G PG   P GPRG  G
Sbjct: 998  PSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAG 1057

Query: 1157 MAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
             +G  G  G  G PGTVGP G+ GP+G +G  G P
Sbjct: 1058 PSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPP 1092



 Score =  112 bits (281), Expect = 2e-24
 Identities = 78/224 (34%), Positives = 92/224 (41%), Gaps = 51/224 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGP------RGPPGVK---------GEKGDHGLPGL 1115
            PGP GP G  G PG  G  GE G PGP      RGPPG           G +G  G PG 
Sbjct: 558  PGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGP 617

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGL---EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
             G+ G  G+ G VG  GP G  GL    G AG+PG  G +G  G+ G  G  G  G  G 
Sbjct: 618  DGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGA 677

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             G  G PGP G  G++GE  +                         P  P          
Sbjct: 678  PGAVGAPGPAGATGDRGEAGAAG-----------------------PAGP---------A 705

Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             P GSPG R +    G  G  G      G+PGA G+ G+ G +G
Sbjct: 706  GPRGSPGERGEVGPAGPNGFAG-PAGAAGQPGAKGERGAKGPKG 748



 Score =  110 bits (275), Expect = 9e-24
 Identities = 86/241 (35%), Positives = 105/241 (43%), Gaps = 36/241 (14%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP------PGVKGEK 1107
            G T P   +  +  +  PGP G +G  G PG  G PG  G  GP GP      PG  G  
Sbjct: 754  GPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPA 813

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGF---QGMA 1158
            G  GL G +G  G  G  G VG  GP      KG  G  GTAG PG PGP+G     G+ 
Sbjct: 814  GKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGIL 873

Query: 1159 GARGTSGERGPPGTVGPTGLPGP---KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHE 1215
            G  G+ GERG PG  G  G PGP    G  G +G P ++ +    V+ A   +  D    
Sbjct: 874  GLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS--PGVNGAPGEAGRDGNPG 931

Query: 1216 NTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQ 1275
            N  P          PG +  G PG + +   PG  G  G      G PG  G +G  G+ 
Sbjct: 932  NDGP----------PGRD--GQPGHKGERGYPGNIGPVG----AAGAPGPHGPVGPAGKH 975

Query: 1276 G 1276
            G
Sbjct: 976  G 976



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 61/188 (32%), Positives = 74/188 (39%), Gaps = 45/188 (23%)

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT----------------VG 1174
            +GP G RG  G  G PGPPG  G  G  G  G  G  GPPG                  G
Sbjct: 32   KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 1175 PTGL------------PGPKGERGEKGEPQSLATLYQLVSQ--ASHVSKFDSFHENTRPP 1220
            P GL            PGP+G +G  GEP          ++  A    K        +P 
Sbjct: 92   PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151

Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----------RGEPGAVGQM 1269
             P  E+ +       G PGT     +PG  G RG   L+G          +GEPGA G+ 
Sbjct: 152  RP-GERGVVGPQGARGFPGTPG---LPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207

Query: 1270 GSPGQQGA 1277
            G+PGQ GA
Sbjct: 208  GTPGQTGA 215


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  144 bits (363), Expect = 5e-34
 Identities = 94/237 (39%), Positives = 111/237 (46%), Gaps = 33/237 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P    GE  P  ++         G  GP GPPG  G NG  G  GFPGP+GPPG  G+ G
Sbjct: 914  PTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973

Query: 1109 DHGLPGLQGHPGHQGI------PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAG 1159
              G PG +G  G QG       PG VG QGP G  G  G  G PGPPGP   +G  G+AG
Sbjct: 974  LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG 1033

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
              GT G+ GP G  G  G PG +G  G++G P  +  L                  N  P
Sbjct: 1034 KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL--------------GLKGNEGP 1079

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P P       PG  P GSPG R  A   G  G  GR    +G PG  G+ G+PG++G
Sbjct: 1080 PGP-------PG--PAGSPGERGPAGAAGPIGIPGRP-GPQGPPGPAGEKGAPGEKG 1126



 Score =  142 bits (358), Expect = 2e-33
 Identities = 97/250 (38%), Positives = 114/250 (45%), Gaps = 56/250 (22%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ---------------G 1093
            PA   GE  PA  +        PG PGPQGPPG  G  G PGE+               G
Sbjct: 1085 PAGSPGERGPAGAAG---PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG 1141

Query: 1094 FPGPR---GPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG 1150
             PGP    GPPG  G+KG+ G PG +G  G +G  G  G  GP+G  G  G +G  G PG
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201

Query: 1151 PRGFQGMAGARGTSGER---GPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHV 1207
            PRG QG+ G +G  G R   GPPG VG  GLPGP GE+GE G+   +             
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMG------------ 1249

Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAV 1266
                       PP P       PG   P G+PG       PG  G  G   E +GEPG  
Sbjct: 1250 -----------PPGP-------PGPRGPSGAPGADGPQGPPGGIGNPGAVGE-KGEPGEA 1290

Query: 1267 GQMGSPGQQG 1276
            G+ G PG+ G
Sbjct: 1291 GEPGLPGEGG 1300



 Score =  140 bits (353), Expect = 8e-33
 Identities = 88/218 (40%), Positives = 97/218 (44%), Gaps = 45/218 (20%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPG------------VKGEKGDHGLPGLQGH 1118
            PGPPG  GP G  G  G  GE+G PGP GPPG             KG+ G  GLPG  G 
Sbjct: 993  PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGP 1052

Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178
            PG +G PG  GL GP G  GL+G  G PGPPGP G  G  G  G +G  G PG  GP G 
Sbjct: 1053 PGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGP 1112

Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSP 1238
            PGP GE+G  GE                            P  P     L+    P+G P
Sbjct: 1113 PGPAGEKGAPGE--------------------------KGPQGPAGRDGLQ---GPVGLP 1143

Query: 1239 GTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G       PGE G  G      GEPG  G  G  G+QG
Sbjct: 1144 GPAGPVGPPGEDGDKGE----IGEPGQKGSKGDKGEQG 1177



 Score =  139 bits (349), Expect = 2e-32
 Identities = 85/209 (40%), Positives = 99/209 (47%), Gaps = 27/209 (12%)

Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            S   GPPGP+GPPG  G  G+PG  GFPG  GPPG  G  G  G PG +G  G  G  G 
Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376

Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187
             G  G  G  G  G  G PGP GP G QG  GA+G +G  GPPG  GP    GP+G  G+
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI---GPQGAPGK 1433

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247
             G P  L  +                      P P+ EQ L     P G PG      +P
Sbjct: 1434 PG-PDGLRGI----------------------PGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470

Query: 1248 GEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G  G  G   E +G PG +G +G PG+QG
Sbjct: 1471 GLKGDSGPKGE-KGHPGLIGLIGPPGEQG 1498



 Score =  134 bits (336), Expect = 7e-31
 Identities = 91/224 (40%), Positives = 105/224 (46%), Gaps = 24/224 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGP G  GP G PG  G PG  G  G  GP G  G +G+ G PG QG+PG QG+PG  G 
Sbjct: 678  PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 1131 QGPKGMRGLEGTAGLPGPP---GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187
             GP G +G  G  GLPG P   GP G  G  G  G  G +GPPG  GP G PGP+G +G 
Sbjct: 738  IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA 797

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQKLE-----------PGT 1232
             G      T  +         K D   +  R    PP P  E   E           PG 
Sbjct: 798  DGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPG- 856

Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PLG PG + K  VPG  G  GR    +G  G++G  G PG  G
Sbjct: 857  -PLGPPGEKGKLGVPGLPGYPGR----QGPKGSIGFPGFPGANG 895



 Score =  132 bits (331), Expect = 3e-30
 Identities = 90/220 (40%), Positives = 104/220 (47%), Gaps = 29/220 (13%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPG  G PG PG+ G  G QG  GP GPPGV G +G  G  G  G  GH G PG  G 
Sbjct: 966  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGE 1025

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV---------GPTGLPGP 1181
            QG  G+ G EGT G PGP G  G  G  G RG  G+RG PG V         GP G PGP
Sbjct: 1026 QGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGP 1085

Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----PLGS 1237
             G  GE+G P   A    +  +               PP P  E K  PG +    P G 
Sbjct: 1086 AGSPGERG-PAGAAGPIGIPGRPGPQG----------PPGPAGE-KGAPGEKGPQGPAGR 1133

Query: 1238 PGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
             G +    +PG  G  G      GE G  G++G PGQ+G+
Sbjct: 1134 DGLQGPVGLPGPAGPVG----PPGEDGDKGEIGEPGQKGS 1169



 Score =  131 bits (330), Expect = 4e-30
 Identities = 97/256 (37%), Positives = 109/256 (42%), Gaps = 35/256 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            PA   G+  P  +         PGP G  G  G  G  G PG  G PG RGP G  G  G
Sbjct: 1043 PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102

Query: 1109 DHGLPGLQGHP---GHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGP------------RG 1153
              G PG QG P   G +G PG  G QGP G  GL+G  GLPGP GP             G
Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIG 1162

Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
              G  G++G  GE+GPPG  GP G  G  G  G  GEP           Q     K D  
Sbjct: 1163 EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------QQGLFGQKGDEG 1216

Query: 1214 HEN-TRPPMPILEQKL--EPGTE----------PLGSPGTRSKALVPGEWGRGGRHLEGR 1260
                  PP P+  Q L   PG +          P G PG R  +  PG  G  G    G 
Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPP-GGI 1275

Query: 1261 GEPGAVGQMGSPGQQG 1276
            G PGAVG+ G PG+ G
Sbjct: 1276 GNPGAVGEKGEPGEAG 1291



 Score =  128 bits (322), Expect = 3e-29
 Identities = 86/215 (40%), Positives = 100/215 (46%), Gaps = 23/215 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVG-- 1129
            G PGP GPPG  G+ G PG  G+PG +GP   KG  G  G PG  G  G +G PG+ G  
Sbjct: 853  GDPGPLGPPGEKGKLGVPGLPGYPGRQGP---KGSIGFPGFPGANGEKGGRGTPGKPGPR 909

Query: 1130 -LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
              +GP G RG  G  G+ G PGP+G  G  G  G  GERGP G  GPTG PGPKG  G  
Sbjct: 910  GQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969

Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243
            G+               H  +     F   T PP P   +  Q     T P+G  G    
Sbjct: 970  GKD----------GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019

Query: 1244 ALVPGEWGRGG-RHLEG-RGEPGAVGQMGSPGQQG 1276
               PGE G  G    EG +G+PG  G  G  G  G
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPG 1054



 Score =  128 bits (321), Expect = 4e-29
 Identities = 85/217 (39%), Positives = 101/217 (46%), Gaps = 33/217 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGH---PGHQGIPGRV 1128
            GPPGP G PG  GR G+ G +G PG  GP G +G  G  GLPG +GH   PG  G PG  
Sbjct: 598  GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGF---------QGMAGARGTSGERGPPGTVGPTGLP 1179
            G  G +G  G  G  GLPG PGPRG           G  G  G  G+ GP G VGP G P
Sbjct: 658  GDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEP 717

Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239
            GP G++G  G  Q L      +                +P +P +     PG +  G PG
Sbjct: 718  GPPGQQGNPG-AQGLPGPQGAIGPPGEKGPLG------KPGLPGM-----PGAD--GPPG 763

Query: 1240 TRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
               K   PGE G       G+G PG  G +G PG +G
Sbjct: 764  HPGKEGPPGEKG-------GQGPPGPQGPIGYPGPRG 793



 Score =  127 bits (320), Expect = 5e-29
 Identities = 92/223 (41%), Positives = 103/223 (46%), Gaps = 52/223 (23%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGP GPQGP G PG +G  GE   PGPRG  G+ G+KGD G  G  G PG  G+ G  G 
Sbjct: 1179 PGPTGPQGPIGQPGPSGADGE---PGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGP 1235

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG------------ERGPPGTVGPTGL 1178
             G KG  G  G  G PGPPGPRG  G  GA G  G            E+G PG  G  GL
Sbjct: 1236 PGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGL 1295

Query: 1179 PG---PKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR-PPMPILEQKLEPGTE- 1233
            PG   P G +GE+GE                  K +S       PP P    K  PG + 
Sbjct: 1296 PGEGGPPGPKGERGE------------------KGESGPSGAAGPPGP----KGPPGDDG 1333

Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P GSPG       PG+ G         GEPG  GQ G PG +G
Sbjct: 1334 PKGSPGPVG---FPGDPG-------PPGEPGPAGQDGPPGDKG 1366



 Score =  127 bits (318), Expect = 9e-29
 Identities = 86/207 (41%), Positives = 96/207 (46%), Gaps = 40/207 (19%)

Query: 1075 GPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPK 1134
            GP GP GL GR         PGP GPPG  G KG+ G  G QG  G QG PG  G  G +
Sbjct: 559  GPAGPMGLTGR---------PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609

Query: 1135 GMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE- 1190
            G  G +G  G+P   GP G RGF G+AG  G  G RG PG  GP G PG  GERG+ GE 
Sbjct: 610  GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEV 669

Query: 1191 -PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
             P+ L                         P  +L  K  PG  P G PG       PG 
Sbjct: 670  GPRGL--------------------PGEPGPRGLLGPKGPPG--PPGPPGVTGMDGQPGP 707

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             G  G     +GEPG  GQ G+PG QG
Sbjct: 708  KGNVG----PQGEPGPPGQQGNPGAQG 730



 Score =  125 bits (315), Expect = 2e-28
 Identities = 82/211 (38%), Positives = 99/211 (46%), Gaps = 39/211 (18%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PGP GPPG  G  G PG+ G   P+GP GV+G  G  G PG +G  G  G  G  G  
Sbjct: 568  GRPGPVGPPGSGGLKGEPGDVG---PQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQT 624

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMA---GARGTSGERGPPGTVGPTGL---PGPKGER 1185
            GPKG RG +G AGLPG  G RG  G +   G  G  GERG  G VGP GL   PGP+G  
Sbjct: 625  GPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLL 684

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G KG P                           PP P     ++    P G+ G + +  
Sbjct: 685  GPKGPP--------------------------GPPGPPGVTGMDGQPGPKGNVGPQGEPG 718

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PG+ G  G     +G PG  G +G PG++G
Sbjct: 719  PPGQQGNPG----AQGLPGPQGAIGPPGEKG 745



 Score =  121 bits (304), Expect = 4e-27
 Identities = 86/226 (38%), Positives = 103/226 (45%), Gaps = 40/226 (17%)

Query: 1071 PGPPGPQGP------PGLPGRNG------TPGEQGFPGPRGPPGVKGEKGDHGLPGLQGH 1118
            PG PG QGP      PG PG NG      TPG+ G  G RGP G +GE+G  G+ G  G 
Sbjct: 873  PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932

Query: 1119 PGHQG------IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
             G+ G       PG  G  GP+G  G  G  G PGPPG  G  G  G RG +G +G  G 
Sbjct: 933  KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             GP G+ GP+G  GE G           + +  H            PP P  EQ L    
Sbjct: 993  PGPPGVVGPQGPTGETGP----------MGERGHPG----------PPGPPGEQGLPGLA 1032

Query: 1233 EPLGSPGTRSKALVPGEWGRGG-RHLEG-RGEPGAVGQMGSPGQQG 1276
               G+ G    A +PG+ G  G R   G RG PG VG +G  G +G
Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG 1078



 Score =  121 bits (303), Expect = 5e-27
 Identities = 86/236 (36%), Positives = 105/236 (44%), Gaps = 45/236 (19%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE---QGFPGPRGP------------------PGVKGEKGD 1109
            PG PG  GPPG PG+ G PGE   QG PGP+GP                   G KGEKG+
Sbjct: 753  PGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE 812

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---------PGPRGFQGMAGA 1160
             G PG +G  G +G  G +G  GP+G  G EG  G  GP         PG +G  G+ G 
Sbjct: 813  DGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL 872

Query: 1161 RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP 1220
             G  G +GP G++G  G PG  GE+G +G P       Q         +  +     R P
Sbjct: 873  PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQ---------RGPTGPRGERGP 923

Query: 1221 MPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              I     +PG  P G+ G    A  PGE G  G      G PG  G  G PG+ G
Sbjct: 924  RGITG---KPG--PKGNSGGDGPAGPPGERGPNGPQ-GPTGFPGPKGPPGPPGKDG 973



 Score =  120 bits (300), Expect = 1e-26
 Identities = 61/119 (51%), Positives = 68/119 (57%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP G  G+PG  G  G  G PGP GPPG  G  G  GL G  G  G +G PG +GL
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKG 1189
             GP G +G +G  GLPGP G  G +G  G  G SG  GPPG  G  G PGPKG +G  G
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSG 1549



 Score =  118 bits (296), Expect = 3e-26
 Identities = 59/120 (49%), Positives = 67/120 (55%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP GPPG  G  G PG +G  GP+G  G  G  G  G PG QG  G +G+PG  G 
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             GPKG +G+ G +G  GPPGP G  G  G +G  G  GP G  G  G PGP G  G  GE
Sbjct: 1512 SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 66/224 (29%), Positives = 88/224 (39%), Gaps = 14/224 (6%)

Query: 1062 SACSCSSETPGPPGPQGPPGLPGRNGTPG----EQGFPGPRGPPGVKGEKGDHGLPGLQG 1117
            +A + +S  P PP  +G   L G          ++ +  P   P     +   G+P  Q 
Sbjct: 380  TADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQD 439

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTA----GLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
               ++GI G  G +G KG   +        G PGP GP G  G  G  G +G+ G PG  
Sbjct: 440  TI-YEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGER 498

Query: 1174 GPTGLPGPKGERGEKGEPQSLATL-YQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
            GP G PG  G  G  G P ++  L ++        SK             IL+Q      
Sbjct: 499  GPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALR 558

Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             P G  G   +    G  G GG     +GEPG VG  G  G QG
Sbjct: 559  GPAGPMGLTGRPGPVGPPGSGGL----KGEPGDVGPQGPRGVQG 598



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 5/140 (3%)

Query: 863  AMEPSAFGGTPTFTLFKDAQLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMT 922
            A   S+ G    + + KDAQL+     +YPA   PE   + L  +  +   +AF +    
Sbjct: 63   ATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSI-LTTVKAKKGSQAFLVSIYN 121

Query: 923  AEDFQPLLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKV 982
             +  Q    + L+ G+ S  + + D         +       +  G +H++ ++V +  V
Sbjct: 122  EQGIQQ---IGLELGR-SPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNV 177

Query: 983  RLYVDCRKVAERPLGEMGSP 1002
             L +DC+K   + L     P
Sbjct: 178  TLILDCKKKTTKFLDRSDHP 197


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  143 bits (361), Expect = 9e-34
 Identities = 104/294 (35%), Positives = 117/294 (39%), Gaps = 71/294 (24%)

Query: 1032 QIVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETP---------------GPPGP 1076
            +++C D   DE + C      +GE CP     C   SE+P               GP GP
Sbjct: 67   KVLCDDVICDETKNCPGAEVPEGECCPV----CPDGSESPTDQETTGVEGPKGDTGPRGP 122

Query: 1077 QGPPGLPGRNGTPGEQGFPGPRGP-------------------------------PGVKG 1105
            +GP G PGR+G PG+ G PGP GP                               PG  G
Sbjct: 123  RGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG 182

Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              G  GLPG  G PG QG  G  G  G  G  G  G  G PGPPG  G  G AG  G  G
Sbjct: 183  PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
            ERGPPG  G  GLPG  G  G KG                  S  D    +  P  P   
Sbjct: 243  ERGPPGPQGARGLPGTAGLPGMKGH--------------RGFSGLDGAKGDAGPAGP--- 285

Query: 1226 QKLEPGTE-PLGSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMGSPGQQG 1276
             K EPG+    G+PG      +PGE GR G       RG  GA G  G PG  G
Sbjct: 286  -KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTG 338



 Score =  140 bits (354), Expect = 6e-33
 Identities = 100/249 (40%), Positives = 113/249 (45%), Gaps = 57/249 (22%)

Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQG------------FP---------GPRGPPGVKGE 1106
            PGPPGP G   P G PG +G PG +G            FP         GP GPPG KG 
Sbjct: 373  PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432

Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGP---------KGMRGLEGTAGLPGPPGPR----- 1152
             G+ G PG +G  G +G PG VG+QGP         +G RG  G  GLPGPPG R     
Sbjct: 433  SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492

Query: 1153 ----GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
                G  G+AG +G +GERG PG  GP G PG  G  GE G P +        S      
Sbjct: 493  RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP--- 549

Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQ 1268
                    T PP P   Q   PG  P G PG R +A V G  G  G      GEPG  G+
Sbjct: 550  -----DGKTGPPGP-AGQDGRPG--PPGPPGARGQAGVMGFPGPKG----AAGEPGKAGE 597

Query: 1269 MGSPGQQGA 1277
             G PG  GA
Sbjct: 598  RGVPGPPGA 606



 Score =  139 bits (349), Expect = 2e-32
 Identities = 95/232 (40%), Positives = 108/232 (46%), Gaps = 49/232 (21%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---------------GPRGPPGVKGEKGDHGLPGL 1115
            PGP GP GP GLPG  G PG QGF                GPRGPPG  G+ GD G  G 
Sbjct: 178  PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP---PGT 1172
             G PG +G P      GP+G RGL GTAGLPG  G RGF G+ GA+G +G  GP   PG+
Sbjct: 238  PGRPGERGPP------GPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 1173 VGPTGLP---GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229
             G  G P   GP+G  GE+G P +           +     D       PP P       
Sbjct: 292  PGENGAPGQMGPRGLPGERGRPGA--------PGPAGARGNDGATGAAGPPGP------- 336

Query: 1230 PGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQQG 1276
              T P G PG        GE G +G R  EG    RGEPG  G  G+ G  G
Sbjct: 337  --TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386



 Score =  135 bits (341), Expect = 2e-31
 Identities = 88/213 (41%), Positives = 102/213 (47%), Gaps = 30/213 (14%)

Query: 1071 PGPPGP------QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            PGPPGP      +GP G  G  G PGE G PGP GP G KG  G  G  G  G PG QGI
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
             G+ G+ G  G RG  G  GLPGP G  G QG +GA   SGERGPPG +GP GL GP GE
Sbjct: 955  AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA---SGERGPPGPMGPPGLAGPPGE 1011

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244
             G +G P +  +  +  S  +   + +                    T P G PG     
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGE--------------------TGPAGPPGAPGAP 1051

Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
              PG  G  G+  + RGE G  G  G  G  GA
Sbjct: 1052 GAPGPVGPAGKSGD-RGETGPAGPAGPVGPVGA 1083



 Score =  135 bits (340), Expect = 3e-31
 Identities = 89/219 (40%), Positives = 101/219 (46%), Gaps = 20/219 (9%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPGR 1127
            PG PGP G PG  G +G  GE+G PGP GPPG+    GE G  G PG +G PG  G PG 
Sbjct: 973  PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGA 1032

Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL---PGPKGE 1184
             G +G  G  G  G  G PG PGP G  G +G RG +G  GP G VGP G     GP+G 
Sbjct: 1033 KGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP 1092

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244
            RG+KGE     T  Q          F        PP    EQ     + P G  G    A
Sbjct: 1093 RGDKGE-----TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147

Query: 1245 LVPGEWGRGGRHLEG-------RGEPGAVGQMGSPGQQG 1276
              PG+ G  G  L G       RG  G  G +G PG  G
Sbjct: 1148 GAPGKDGLNG--LPGPIGPPGPRGRTGDAGPVGPPGPPG 1184



 Score =  129 bits (325), Expect = 1e-29
 Identities = 89/228 (39%), Positives = 97/228 (42%), Gaps = 49/228 (21%)

Query: 1072 GPPGPQGP------------------PGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDH 1110
            GPPGP GP                  PG PG  G PG QG PG RG    PG KG++GD 
Sbjct: 689  GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA 748

Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170
            G  G  G PG  G+ G  G  GP G  G  G  G  GP GP G  G  GA G  GE GPP
Sbjct: 749  GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230
            G  G  G PG  G+ G KGEP                +K D+      PP P        
Sbjct: 809  GPAGFAGPPGADGQPGAKGEPGDAG------------AKGDA-----GPPGP-------- 843

Query: 1231 GTEPLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
               P G PG       PG  G RG     G  G PGA G++G PG  G
Sbjct: 844  -AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890



 Score =  129 bits (324), Expect = 2e-29
 Identities = 83/207 (40%), Positives = 95/207 (45%), Gaps = 3/207 (1%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP GP+GPPG PG+NG  GE G PG  G  G  G +G  GLPG  G PG +G  G  GL 
Sbjct: 215  GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G KG  G  G  G PG PG  G  G  G RG  GERG PG  GP G  G  G  G  G P
Sbjct: 275  GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251
                         +  +K ++  +  R        + EPG  P G  G    A  PG  G
Sbjct: 335  GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG--PPGPAGAAGPAGNPGADG 392

Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            + G      G PG  G  G PG +G S
Sbjct: 393  QPGAK-GANGAPGIAGAPGFPGARGPS 418



 Score =  129 bits (324), Expect = 2e-29
 Identities = 89/230 (38%), Positives = 103/230 (44%), Gaps = 28/230 (12%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            GE+ P+  +  + +   PG  G  GPPG  G  G PG  G PG +G PG  G KGD G P
Sbjct: 782  GESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP 841

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            G  G  G  G  G VG  G KG RG  G  G  G PG  G  G  G  G +G  GPPG  
Sbjct: 842  GPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPA 901

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G  GP+GE G  G P  +                        PP P  E K  PG +
Sbjct: 902  GKEGGKGPRGETGPAGRPGEVGP--------------------PGPPGPAGE-KGSPGAD 940

Query: 1234 -PLGSPGTRSKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQGAS 1278
             P G+PGT     + G+ G  G  L G    RG PG  G  G PG+QG S
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVVG--LPGQRGERGFPGLPGPSGEPGKQGPS 988



 Score =  127 bits (320), Expect = 5e-29
 Identities = 91/240 (37%), Positives = 104/240 (43%), Gaps = 39/240 (16%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            R G   PA       ++   GPPGP    GPPG PG  G  GE G  GPRG  G +G +G
Sbjct: 312  RPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRG 371

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168
            + G PG  G  G  G PG  G  G KG  G  G AG PG PG R   G +G +G  G  G
Sbjct: 372  EPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR---GPSGPQGPGGPPG 428

Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-- 1226
            P G  G  G PG KG+ G KGEP  +                        PP P  E+  
Sbjct: 429  PKGNSGEPGAPGSKGDTGAKGEPGPVGV--------------------QGPPGPAGEEGK 468

Query: 1227 ---KLEPGTEPL-------GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
               + EPG   L       G PG+R      G  G  G   E RG PG  G  GSPG+ G
Sbjct: 469  RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE-RGSPGPAGPKGSPGEAG 527



 Score =  127 bits (318), Expect = 9e-29
 Identities = 100/296 (33%), Positives = 121/296 (40%), Gaps = 31/296 (10%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P GE G P + GF     +A  +GP     +                  +     A R G
Sbjct: 483  PPGERGGPGSRGFPGADGVAGPKGPAGERGS------------PGPAGPKGSPGEAGRPG 530

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
            E         + S  +PGP G  GPPG  G++G PG  G PG RG  GV G  G  G  G
Sbjct: 531  EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAG 590

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174
              G  G +G+PG  G  GP G  G  G  G PGP GP G +G  G  G+ G +G PG  G
Sbjct: 591  EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650

Query: 1175 PTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE--PGT 1232
            P   PG  G+ GE+G P  L       S A     F        PP P   +     PG 
Sbjct: 651  P---PGEAGKPGEQGVPGDLGA--PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 1233 E----PLGSPGTRSKALVPGEWG----RGGRHLEG----RGEPGAVGQMGSPGQQG 1276
            +      G+PG       PG  G    RG   L G    RG+ G  G  GSPG+ G
Sbjct: 706  DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761



 Score =  124 bits (311), Expect = 6e-28
 Identities = 90/242 (37%), Positives = 96/242 (39%), Gaps = 51/242 (21%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG------------- 1117
            PG PG QG PGL G  G  G  G PGP+G  G  G KG  G PG  G             
Sbjct: 715  PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774

Query: 1118 --HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA------------RGT 1163
               PG +G  G  G  GP G RG  G  G PGPPGP GF G  GA             G 
Sbjct: 775  AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA 834

Query: 1164 SGERGPPGTVGPTGLPGP---------KGERGEKGEPQSLATLYQLVSQASHVSKFDSFH 1214
             G+ GPPG  GP G PGP         KG RG  G P +          A  V       
Sbjct: 835  KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG----FPGAAGRVGP-PGPS 889

Query: 1215 ENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQ 1274
             N  PP P      E G  P G  G   +   PGE G         G PG  G+ GSPG 
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGR---PGEVG-------PPGPPGPAGEKGSPGA 939

Query: 1275 QG 1276
             G
Sbjct: 940  DG 941



 Score =  124 bits (310), Expect = 8e-28
 Identities = 97/285 (34%), Positives = 116/285 (40%), Gaps = 73/285 (25%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLP------------------GRNGTPG 1090
            PA +DG   P         +   G PGP+G  G P                  G++G  G
Sbjct: 558  PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617

Query: 1091 EQGFPGPRGPPGVKGEKGDHGLPGLQ------------GHPGHQGIPGRVGLQGP---KG 1135
             QG PGP GP G +GE+G  G PG Q            G PG QG+PG +G  GP   +G
Sbjct: 618  AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG 677

Query: 1136 MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------------------PGTVGPTG 1177
             RG  G  G+ GPPGP G +G  GA G  G +G                   PG  G  G
Sbjct: 678  ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGS 1237
            LPGPKG+RG+ G              A      D     T P  P       PG  P G+
Sbjct: 738  LPGPKGDRGDAGP-----------KGADGSPGKDGVRGLTGPIGP-------PG--PAGA 777

Query: 1238 PGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGASTQ 1280
            PG + ++   G  G  G R   G RGEPG  G  G  G  GA  Q
Sbjct: 778  PGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ 822



 Score =  121 bits (303), Expect = 5e-27
 Identities = 85/247 (34%), Positives = 97/247 (39%), Gaps = 42/247 (17%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGL---PGRNGTPGEQGFPGPRGP----- 1100
            P    G   PA       +   PGP G  GPPG    PG  G PG  G  GP+GP     
Sbjct: 453  PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG 512

Query: 1101 ----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPG 1150
                      PG  G  G+ GLPG +G  G  G PG  G  GP G  G +G  G PGPPG
Sbjct: 513  SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG 572

Query: 1151 PRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210
             RG  G+ G  G  G  G PG  G  G+PGP G  G  G+                    
Sbjct: 573  ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK-------------------- 612

Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270
            D       PP P           P GSPG +      G  G  G+     GE G  G +G
Sbjct: 613  DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK----PGEQGVPGDLG 668

Query: 1271 SPGQQGA 1277
            +PG  GA
Sbjct: 669  APGPSGA 675



 Score =  105 bits (262), Expect = 3e-22
 Identities = 72/217 (33%), Positives = 83/217 (38%), Gaps = 72/217 (33%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P+   G+  P+  S         GPPG  GPPG  GR G PG +G PG  G PG KG++G
Sbjct: 978  PSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037

Query: 1109 DHGLPGLQGHPGHQGIPGRVGL------------------------------QGP----- 1133
            + G  G  G PG  G PG VG                               QGP     
Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKG 1097

Query: 1134 ----------KGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG--------- 1174
                      KG RG  G  G PGPPG  G QG +GA G +G RGPPG+ G         
Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157

Query: 1175 ------------------PTGLPGPKGERGEKGEPQS 1193
                              P G PGP G  G  G P +
Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 61/152 (40%), Positives = 68/152 (44%), Gaps = 22/152 (14%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVK 1104
            GET PA  +         GP GPQGP G  G  G  G++G  G         P GPPG  
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 1105 GEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTS 1164
            GE+G     G  G  G +G PG  G  G  G+ GL G     GPPGPRG  G AG  G  
Sbjct: 1127 GEQGP---SGASGPAGPRGPPGSAGAPGKDGLNGLPGPI---GPPGPRGRTGDAGPVGPP 1180

Query: 1165 GERGPPGTVGPTG-------LPGPKGERGEKG 1189
            G  GPPG  GP         LP P  E+   G
Sbjct: 1181 GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 45/141 (31%), Positives = 54/141 (38%), Gaps = 35/141 (24%)

Query: 1138 GLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATL 1197
            G+EG  G  GP GPRG  G  G  G  G+ G PG  GP G PGP G  G           
Sbjct: 109  GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGN---------- 158

Query: 1198 YQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHL 1257
                 Q S+      + E +   + +      PG  P+G  G R     PG         
Sbjct: 159  --FAPQLSY-----GYDEKSTGGISV------PG--PMGPSGPRGLPGPPG--------- 194

Query: 1258 EGRGEPGAVGQMGSPGQQGAS 1278
               G  G  G  G PG+ GAS
Sbjct: 195  -APGPQGFQGPPGEPGEPGAS 214


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  143 bits (361), Expect = 9e-34
 Identities = 93/227 (40%), Positives = 112/227 (49%), Gaps = 32/227 (14%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE---QGFPGPRGPPGVKGEKG------------DHGLPGL 1115
            PGP G  G PG+PG  GTPGE   QG PG RGPPG++G KG            + G  GL
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
            +G PG QG PGR G QG  G RG  G+ G PG PGP G  G  G  G  G +GP G +GP
Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE-- 1233
             G  GPKG  G  GEP        L  +A    K D     T     ++ Q+ EPG E  
Sbjct: 1143 PGEMGPKGPPGAVGEP-------GLPGEAG--MKGDLGPLGTPGEQGLIGQRGEPGLEGD 1193

Query: 1234 --PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
              P+G  G +     PG  G  G     +G+ G +G+ G PG  G +
Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGE----KGQEGLMGEDGPPGPPGVT 1236



 Score =  140 bits (353), Expect = 8e-33
 Identities = 93/233 (39%), Positives = 108/233 (46%), Gaps = 36/233 (15%)

Query: 1071 PGPPGPQGPPG---LPGRNGT------PGEQGFPGPRG---PPGVKGEKGDHGLPGLQGH 1118
            PGPPGP+G PG    PG NG       PG +G PGPRG   P G +G  G  G PGL+G 
Sbjct: 903  PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962

Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178
            PG +G PGR GL G KG  G  G  G  G  G  GF G+ G  G  GE+G  G +GP G+
Sbjct: 963  PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022

Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----P 1234
            PGPKG  G  G P  + T  +   Q             +R P  +   K   G      P
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGP---------PGSRGPPGMRGAKGRRGPRGPDGP 1073

Query: 1235 LGSPGTRSKALVPGEWGRGGR-----------HLEGRGEPGAVGQMGSPGQQG 1276
             G  G+R     PG  GR GR           HL  RG PG  G  G PG +G
Sbjct: 1074 AGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKG 1126



 Score =  138 bits (347), Expect = 4e-32
 Identities = 105/293 (35%), Positives = 123/293 (41%), Gaps = 48/293 (16%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P G+ G P   G   L  +  ARGPR     +    L           D       + DG
Sbjct: 629  PKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDG 688

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
                  +   S +   PGPPG +G  G PG  G PGEQG PGP G PG KG  G  GLPG
Sbjct: 689  AKGDMGLPGLSGN---PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPG 745

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---G 1171
              G PG +G  G +GL G  G+ G +G  GLPG PG RG  GM G  G  GERGPP   G
Sbjct: 746  PVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDG 805

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
              G  GLPGP G  G  G+   L                                     
Sbjct: 806  NPGELGLPGPPGVPGLIGDLGVLG------------------------------------ 829

Query: 1232 TEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQG-ASTQGL 1282
              P+G PG +    + G  G  G  L+G +GE G  G  G PG QG   +QGL
Sbjct: 830  --PIGYPGPKGMKGLMGSVGEPG--LKGDKGEQGVPGVSGDPGFQGDKGSQGL 878



 Score =  137 bits (344), Expect = 9e-32
 Identities = 82/218 (37%), Positives = 109/218 (50%), Gaps = 36/218 (16%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPG +GP G  G  G PG+ G+PG  G  G++G+ G  G PG   HPG +G PG  G 
Sbjct: 1342 PGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPG---HPGPRGWPGPKGS 1398

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
            +G +G +G +G AG PG  G +G QG+ G RG  G +G  G  GP GLPG  G+ G++GE
Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL----GSPGTRSKALV 1246
                                    +    PM    ++  PG   L    G PG + ++ +
Sbjct: 1459 QGD---------------------DGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGL 1497

Query: 1247 PGEWG-RGGRHLEGR-------GEPGAVGQMGSPGQQG 1276
            PG+ G  G R  EGR       GEPG+ GQ G  G+ G
Sbjct: 1498 PGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMG 1535



 Score =  129 bits (325), Expect = 1e-29
 Identities = 90/232 (38%), Positives = 107/232 (46%), Gaps = 24/232 (10%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPGLQ---GHPG 1120
            S    GP G QG  G PGR G  G QG PGPR   G  G++G  G  GLPG     G  G
Sbjct: 1398 SKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG 1457

Query: 1121 HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPG 1180
             QG  G  G  GP G RG  G AGLPG  GP GF+G +G  G  G  G  GT G TGLPG
Sbjct: 1458 EQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPG 1517

Query: 1181 PKGERGEKGEP--------QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG- 1231
             +GE G KG+P          +A L+        +  F    +  R P  ++ ++   G 
Sbjct: 1518 NQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG-FKGI-QGPRGPPGLMGKEGIVGP 1575

Query: 1232 ---TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280
                 P G PG +      G+WG  G     RG PG  G+ G PG  G   Q
Sbjct: 1576 LGILGPSGLPGPKGDKGSRGDWGLQG----PRGPPGPRGRPGPPGPPGGPIQ 1623



 Score =  128 bits (321), Expect = 4e-29
 Identities = 86/232 (37%), Positives = 105/232 (45%), Gaps = 51/232 (21%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRG---------PPGVKGEKGDHGLPGLQGHPGHQ 1122
            G PGP G PGL G  G  G  G+PGP+G          PG+KG+KG+ G+PG+ G PG Q
Sbjct: 811  GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQ 870

Query: 1123 G---------IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            G          PG  G  GP G  G +G+ G PGPPGP GF G  G  G +G  G  G  
Sbjct: 871  GDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKP 930

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  GLPGP+G+ G +G+   +                        P  P LE   +PG +
Sbjct: 931  GARGLPGPRGQLGPEGDEGPMGP----------------------PGAPGLEG--QPGRK 966

Query: 1234 PL-GSPGTRSKALVPGEWGRGGRHLEGR--------GEPGAVGQMGSPGQQG 1276
               G PG       PG+ GR G   E          GEPG VG+ G  G  G
Sbjct: 967  GFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018



 Score =  128 bits (321), Expect = 4e-29
 Identities = 89/216 (41%), Positives = 103/216 (47%), Gaps = 42/216 (19%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G  GPPG+PG  G+ G  G PG  G PG   E G  G PG +G PG +G  GR G +
Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPG---EPGPQGPPGSRGPPGMRGAKGRRGPR 1068

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGF------QGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185
            GP G  G +G+ GL GPPGP+G       QG+AG RG  G RG PG  GP+G PG KG  
Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244
            GE G PQ                          P  PI      PG   P G PG   + 
Sbjct: 1129 GEPG-PQG-------------------------PQGPI----GPPGEMGPKGPPGAVGEP 1158

Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQGAS 1278
             +PGE G  G    L   GE G +GQ G PG +G S
Sbjct: 1159 GLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDS 1194



 Score =  126 bits (316), Expect = 2e-28
 Identities = 87/227 (38%), Positives = 106/227 (46%), Gaps = 33/227 (14%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGP---------RGPPGVKGEKGDHGLPGLQGHPGH 1121
            PG PGP GPPG  G  G PG QG  GP         +GPPG  GE G  G  G++G  G 
Sbjct: 1113 PGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGP 1172

Query: 1122 QGIPGRVGLQGPKGMRGLEGTAGLPGP---------PGPRGFQGMAGARGTSGERGPPGT 1172
             G PG  GL G +G  GLEG +G  GP         PGP G  G  G  G  GE GPPG 
Sbjct: 1173 LGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGP 1232

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             G TG+ GP+G+ G++GE            +    +K    ++     M +      PGT
Sbjct: 1233 PGVTGVRGPEGKSGKQGE------------KGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280

Query: 1233 E-PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
              P GS G+      PG  G +G   L G  G  G VG +G PG +G
Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKG 1327



 Score =  124 bits (312), Expect = 4e-28
 Identities = 88/231 (38%), Positives = 106/231 (45%), Gaps = 57/231 (24%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPGHQGIP 1125
            G  GP GP GL G  G PG  G  G +G  G+ GE G  G PG+      +G  G QG  
Sbjct: 1192 GDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEK 1251

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT------------- 1172
            GR G +G KG +G  G  G+PG PGP G  G  G+RG+ G  G PG              
Sbjct: 1252 GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311

Query: 1173 -----VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQK 1227
                 VGP G PGPKGE+GE+GE                    D   E   PP P     
Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGE--------------------DGKAEG--PPGP----- 1344

Query: 1228 LEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276
              PG   P+G  G R +   PG  G+ G  ++G RG+PG  GQ G PG +G
Sbjct: 1345 --PGDRGPVGDRGDRGEPGDPGYPGQEG--VQGLRGKPGQQGQPGHPGPRG 1391



 Score =  117 bits (292), Expect = 9e-26
 Identities = 94/275 (34%), Positives = 116/275 (42%), Gaps = 69/275 (25%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL--------------- 1115
            PG  G  GP G PG  G PG QG PGP G PG KG +G  GLPGL               
Sbjct: 720  PGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779

Query: 1116 ------------------QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP---PGPRGF 1154
                              +G PG  G PG +GL GP G+ GL G  G+ GP   PGP+G 
Sbjct: 780  PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839

Query: 1155 QGMAGA------RGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
            +G+ G+      +G  GE+G PG  G  G  G KG +G  G P +      L       S
Sbjct: 840  KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899

Query: 1209 -------KFDSFHENTRPP----------------MPILEQKLEP-GTE-PLGSPGTRSK 1243
                     + F  +  PP                +P    +L P G E P+G PG    
Sbjct: 900  IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 1244 ALVPGEWGRGGR-HLEG-RGEPGAVGQMGSPGQQG 1276
               PG  G  GR  L+G +GEPG  G+ G  G+QG
Sbjct: 960  EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQG 994



 Score =  114 bits (284), Expect = 8e-25
 Identities = 80/228 (35%), Positives = 100/228 (43%), Gaps = 18/228 (7%)

Query: 990  KVAERPLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELP 1049
            K AE P G+ G   A G   +  L    GPR       L+ +         D     +  
Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458

Query: 1050 ASRDGETCPAFVSACSCSSETPGPPGPQGPPGL------------PGRNGTPGEQGFPGP 1097
               DG+  P   +    +    G PG QGPPG             PG+ GT G  G PG 
Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGN 1518

Query: 1098 RGPPGVKGEKGDHG---LPGLQGHPGHQGIPGRVG---LQGPKGMRGLEGTAGLPGPPGP 1151
            +G PG KG+ GD G    PG+ G  G +G PG +G   +QGP+G  GL G  G+ GP G 
Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578

Query: 1152 RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQ 1199
             G  G+ G +G  G RG  G  GP G PGP+G  G  G P     L Q
Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQ 1626



 Score =  111 bits (278), Expect = 4e-24
 Identities = 86/261 (32%), Positives = 103/261 (39%), Gaps = 64/261 (24%)

Query: 1071 PGPPGP---------------------------------QGPPGLPGRNGTPGEQGFPGP 1097
            PGPPG                                   G PG PG  GTPG +G  G 
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 1098 RGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEG----TAGLPGPPGPR- 1152
             GP G  G  G  G PGL G+ GH+GI G +G  GPKG +G +G      G PGPPG R 
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349

Query: 1153 -----------------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLA 1195
                             G +G+ G RG  G++G PG  GP G PGPKG +G +G      
Sbjct: 1350 PVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK-- 1407

Query: 1196 TLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGR 1255
               Q  + A              P   +  Q LE    P G PG   +A   GE G  G 
Sbjct: 1408 ---QGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDG- 1463

Query: 1256 HLEGRGEPGAVGQMGSPGQQG 1276
                 G  G  G+ G+PG  G
Sbjct: 1464 ---DPGPMGPAGKRGNPGVAG 1481



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 74/206 (35%), Positives = 91/206 (44%), Gaps = 35/206 (16%)

Query: 1090 GEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
            G   FP   GPPG    KGD GLPG  G PG  GIP   G +GP+G  G  G  GLPGPP
Sbjct: 616  GSTPFPLLMGPPGP---KGDCGLPGPPGLPGLPGIP---GARGPRGPPGPYGNPGLPGPP 669

Query: 1150 GPR---------------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSL 1194
            G +               G +G  G  G SG  GPPG  G  G PGP G  GE+G+P   
Sbjct: 670  GAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPG-- 727

Query: 1195 ATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL----GSPGTRSKALVPGEW 1250
                    + S  +K     +    P+     K   G   L    G PG+  +  +PG  
Sbjct: 728  -------PEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVP 780

Query: 1251 GRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G+ G+ +   G PG  G+ G PG  G
Sbjct: 781  GKRGK-MGMPGFPGVFGERGPPGLDG 805



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 26/80 (32%), Positives = 31/80 (38%), Gaps = 19/80 (23%)

Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-------R 1260
            S +  FH     P P+L          +G PG +    +PG  G  G  L G       R
Sbjct: 607  SGYSIFHLAGSTPFPLL----------MGPPGPKGDCGLPGPPGLPG--LPGIPGARGPR 654

Query: 1261 GEPGAVGQMGSPGQQGASTQ 1280
            G PG  G  G PG  GA  Q
Sbjct: 655  GPPGPYGNPGLPGPPGAKGQ 674


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  142 bits (359), Expect = 2e-33
 Identities = 96/220 (43%), Positives = 106/220 (48%), Gaps = 38/220 (17%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP---GLQGHPGHQGIPGR 1127
            PGPPGP GPPG PG++G  GE G PG  GPPG KG  G  G P   GL G PG  G+ GR
Sbjct: 31   PGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGR 90

Query: 1128 VGLQGPKGMRGLEGTAGLPGP--------PGPRGFQGMAGARGTSGERGPPGTVGPTGLP 1179
             G  GPKG  G  G+ G PGP        PGP G  G++G  G  G RGPPG  G  GLP
Sbjct: 91   DGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLP 150

Query: 1180 GPKGERGEKGEPQSL---ATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLG 1236
            GP G  G  G P  L   AT  Q  S                PP P       PG  P G
Sbjct: 151  GPPGPPGPPGHPGVLPEGATDLQCPSIC--------------PPGP-------PG--PPG 187

Query: 1237 SPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PG +      GE G  G+  E +G+PG  G  G PG  G
Sbjct: 188  MPGFKGPTGYKGEQGEVGKDGE-KGDPGPPGPAGLPGSVG 226



 Score =  138 bits (348), Expect = 3e-32
 Identities = 94/237 (39%), Positives = 114/237 (48%), Gaps = 38/237 (16%)

Query: 1071 PGPPGPQGPPGLPG---------------RNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115
            PGPPGP GPPG PG                 G PG  G PG +GP G KGE+G+ G  G 
Sbjct: 150  PGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGE 209

Query: 1116 QGHPGHQG---IPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
            +G PG  G   +PG VGLQGP+G+RGL G  G PG  GP GF+G  G  G  G+ G  G 
Sbjct: 210  KGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGE 269

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE-QKLEPG 1231
             GP G  GPKG+ G  G P+    +     +     K      + +  +P L+ QK E G
Sbjct: 270  RGPEGFRGPKGDLGRPG-PKGTPGVAGPSGEPGMPGK------DGQNGVPGLDGQKGEAG 322

Query: 1232 TE-------PLGSPGTRSKALVPGEWGRGGRHLE-----GRGEPGAVGQMGSPGQQG 1276
                     P G PG   +A   GE G  GR  E       GEPG  G  G PG++G
Sbjct: 323  RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERG 379



 Score =  124 bits (312), Expect = 4e-28
 Identities = 91/252 (36%), Positives = 110/252 (43%), Gaps = 39/252 (15%)

Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGP---QGPPGLPGRN---GTPGEQGFPGPRGPP 1101
            LP       CP+      C    PGPPG    +GP G  G     G  GE+G PGP GP 
Sbjct: 165  LPEGATDLQCPSI-----CPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPA 219

Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIP---GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158
            G+ G  G  G  GL+G PG  G P   G +G +GP G+ G  G AG  G  GP GF+G  
Sbjct: 220  GLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPK 279

Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218
            G  G  G +G PG  GP+G PG  G+ G+ G P        L  Q     +  +  E   
Sbjct: 280  GDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP-------GLDGQKGEAGRNGAPGEKGP 332

Query: 1219 PPMPILE-------QKLEPG-------TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPG 1264
              +P L        +K E G         P G PG    A +PGE G  G     RG  G
Sbjct: 333  NGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGH----RGSAG 388

Query: 1265 AVGQMGSPGQQG 1276
            A+G  G PG  G
Sbjct: 389  ALGPQGPPGAPG 400



 Score =  120 bits (300), Expect = 1e-26
 Identities = 87/233 (37%), Positives = 109/233 (46%), Gaps = 40/233 (17%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  GP G PG+PG  G PGE+G  G RG  G  G +G  G PG++G  G +G  G  GL 
Sbjct: 358  GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP 417

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            GP+G+RG  G  G  G  GP+G QG+AG+ G  G++   G +GP+GL GPKGE G +GE 
Sbjct: 418  GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDK---GELGPSGLVGPKGESGSRGEL 474

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE--PG-TEPLGSPGTRS------ 1242
                T  Q  +  S V           PP P+  Q +   PG T   G PG  +      
Sbjct: 475  GPKGT--QGPNGTSGVQGVPG------PPGPLGLQGVPGVPGITGKPGVPGKEASEQRIR 526

Query: 1243 -------------------KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                               K L PG  GR G      G PG  G +G PG +G
Sbjct: 527  ELCGGMISEQIAQLAAHLRKPLAPGSIGRPG-PAGPPGPPGPPGSIGHPGARG 578



 Score =  119 bits (299), Expect = 1e-26
 Identities = 87/234 (37%), Positives = 102/234 (43%), Gaps = 48/234 (20%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPG------------PRGPPGVKGEKGDHGLP----- 1113
            PG PGP GP G PG+ G PGE G PG            P GP G  GE+G  G P     
Sbjct: 55   PGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGL 114

Query: 1114 ---GLQGHPGHQGI---PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGER 1167
               GL G PG  G+   PG +GL+GP G  GL G  G PGPPGP G  G+     T  + 
Sbjct: 115  GGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQC 174

Query: 1168 G---PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
                PPG  GP G+PG KG  G KGE   +                D    +  PP P  
Sbjct: 175  PSICPPGPPGPPGMPGFKGPTGYKGEQGEVGK--------------DGEKGDPGPPGP-- 218

Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH--LEGRGEPGAVGQMGSPGQQG 1276
                 PG+  +G  G R    +PG  G  G    +  RG PG  G  G  G +G
Sbjct: 219  --AGLPGS--VGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG 268



 Score =  118 bits (295), Expect = 4e-26
 Identities = 88/239 (36%), Positives = 113/239 (47%), Gaps = 25/239 (10%)

Query: 1070 TPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPGVKGEKGDHGLPGL------QGHPG 1120
            TPG  GP G PG+PG+   NG PG  G  G  G  G  GEKG +GLPGL      +G  G
Sbjct: 290  TPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKG 349

Query: 1121 HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP---------G 1171
             +G  G +G  GP G  G+ G AG+PG  G  G +G AGA G  G  G P         G
Sbjct: 350  ERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKG 409

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
            ++G  GLPGP+G RG+ G+            Q    S      +    P  ++  K E G
Sbjct: 410  SMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESG 469

Query: 1232 TE----PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGASTQGLWE 1284
            +     P G+ G    + V G  G  G   L+G  G PG  G+ G PG++ AS Q + E
Sbjct: 470  SRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKE-ASEQRIRE 527



 Score =  117 bits (293), Expect = 7e-26
 Identities = 81/213 (38%), Positives = 102/213 (47%), Gaps = 22/213 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGD---HGLPGLQGHPGHQGIPGRV 1128
            G PGP+G PG+ G +G PG  G  G  G PG+ G+KG+   +G PG +G  G  G+PGR 
Sbjct: 283  GRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRA 342

Query: 1129 GLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185
            G +G KG RG  G  G  GP   PG  G  GM G RG +G RG  G +GP G PG  G R
Sbjct: 343  GSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVR 402

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G+  S+        Q       D      R P             P G  G      
Sbjct: 403  GFQGQKGSMGDPGLPGPQGLRGDVGD------RGP--------GGAAGPKGDQGIAGSDG 448

Query: 1246 VPGEWGR-GGRHLEG-RGEPGAVGQMGSPGQQG 1276
            +PG+ G  G   L G +GE G+ G++G  G QG
Sbjct: 449  LPGDKGELGPSGLVGPKGESGSRGELGPKGTQG 481



 Score =  117 bits (292), Expect = 9e-26
 Identities = 82/226 (36%), Positives = 102/226 (45%), Gaps = 20/226 (8%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP GP G PG+ G  G  G  G PG  GP G++G+ GD G  G  G  G QGI G  GL 
Sbjct: 391  GPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP 450

Query: 1132 G------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185
            G      P G+ G +G +G  G  GP+G QG  G  G  G  GPPG +G  G+PG  G  
Sbjct: 451  GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT-------EPLGSP 1238
            G+ G P   A+  ++      +       E        L + L PG+        P G P
Sbjct: 511  GKPGVPGKEASEQRIRELCGGM-----ISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565

Query: 1239 GTRSKALVPGEWGRGG-RHLEGR-GEPGAVGQMGSPGQQGASTQGL 1282
            G       PG  G  G R   G  G+PG  G  G  G +GA+  GL
Sbjct: 566  GPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGL 611



 Score =  105 bits (262), Expect = 3e-22
 Identities = 80/241 (33%), Positives = 100/241 (41%), Gaps = 60/241 (24%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            S   PG  G  GP GL G  G  G +G  GP+G  G  G  G  G+PG  G  G QG+PG
Sbjct: 446  SDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPG 505

Query: 1127 RVGLQGPKGMRGLE-------------------------------GTAGLPGPPGPRGFQ 1155
              G+ G  G+ G E                               G+ G PGP GP G  
Sbjct: 506  VPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565

Query: 1156 GMAGARGTSGERGPPGTVGPTGL---PGPKGERGEKGEPQSLATLYQLVSQASHVSKFDS 1212
            G  G+ G  G RGPPG  GPTG    PGP+G +G++G+            + +  +  D 
Sbjct: 566  GPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGD------------KGAAGAGLDG 613

Query: 1213 FHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSP 1272
               +  P  P    +  PGT   G  G       PGE G  G      G PGA+G  G+P
Sbjct: 614  PEGDQGPQGP----QGVPGTSKDGQDG------APGEPGPPG----DPGLPGAIGAQGTP 659

Query: 1273 G 1273
            G
Sbjct: 660  G 660



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 57/131 (43%), Positives = 69/131 (52%), Gaps = 11/131 (8%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQG--IPGRV 1128
            PGP GP GPPG PG  G PG +G PG RGP G  G+ G  G  G +G  G  G  + G  
Sbjct: 556  PGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPE 615

Query: 1129 GLQGPKGMRGLEGTA-----GLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGP-K 1182
            G QGP+G +G+ GT+     G PG PGP G  G+ GA G    +G PG    +   G   
Sbjct: 616  GDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGA---QGTPGICDTSACQGAVL 672

Query: 1183 GERGEKGEPQS 1193
            G  GEK   +S
Sbjct: 673  GGVGEKSGSRS 683



 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 64/178 (35%), Positives = 71/178 (39%), Gaps = 45/178 (25%)

Query: 1111 GLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170
            GLPG  G PG  G PG+ G+ G  G        GLPGPPGP+G  G  G  G +G  G P
Sbjct: 29   GLPGPPGPPGPPGKPGQDGIDGEAG------PPGLPGPPGPKGAPGKPGKPGEAGLPGLP 82

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230
            G  G TG  GP G +G  GE  SL                        PP P       P
Sbjct: 83   GVDGLTGRDGPPGPKGAPGERGSLG-----------------------PPGP-------P 112

Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEGR-------GEPGAVGQMGSPGQQGASTQG 1281
            G    G PG   +A V G    GG  L G        G PG  G  G PG  G   +G
Sbjct: 113  GLGGKGLPGPPGEAGVSGP--PGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEG 168


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  142 bits (358), Expect = 2e-33
 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122
            GPPGP G PG PG+ G+PG  G  G RG PG KGE+GD G PG          +G PG +
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G    PG  G +G  GM GL+G  GLP   GPPGPRG  G  G  G  G RG PG++G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
            G+PG KG+RG  G P       L  ++ L            + E TRP  P         
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067

Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
              P G PG        GE G+ G   HL   G  GA G  GSPG  G
Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113



 Score =  138 bits (347), Expect = 4e-32
 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            PGPPGP G PGLPG  G  GE G P      GP GP G  G  G  GLPG  G  G  G 
Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177
             G  GL GP G+RG  G  G PG PGP   RG QG  G  G +GE+G  G +    GP G
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236
             PG +G +G++G P       +  +      +  +  E   P  P L   + PG T   G
Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242

Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282
             PG+R     PG  G  G H+ G             +G PG  G MG PG+ GA  T GL
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302



 Score =  129 bits (325), Expect = 1e-29
 Identities = 85/210 (40%), Positives = 99/210 (47%), Gaps = 31/210 (14%)

Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126
            PGPPG  G   PG  G  G PG +G PG  GPPG  G    G  G  G  GHPG +G PG
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  GT GLPGP G  GFQG  G +G  G  G  G++GP G  GPKG  G
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246
             +G+P +L              K  S   +  PP          GT   G PG + +   
Sbjct: 1344 VRGDPGTL--------------KIISLPGSPGPP----------GTP--GEPGMQGEPGP 1377

Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            PG  G  G     RG+PG  G+ G+PG  G
Sbjct: 1378 PGPPGNLGP-CGPRGKPGKDGKPGTPGPAG 1406



 Score =  127 bits (320), Expect = 5e-29
 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%)

Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107
            S S+  PGPPGP GPPG PG  G P         G+ G PGP G PG+         G K
Sbjct: 649  SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159
            GD G PG +      G  G  G+PG+ GL G KG     + G  G PG PG RG  G  G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203
              G  G  G PGT G  GL GP+G+ G+ G P                Q L  L  L  Q
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828

Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263
                 K     +   P +P L++   PG    GSPG      +PG  G  G  L  RG P
Sbjct: 829  QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876

Query: 1264 GAVGQMGSPGQQG 1276
            G  G +G PG+ G
Sbjct: 877  GNPGILGPPGEDG 889



 Score =  123 bits (309), Expect = 1e-27
 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%)

Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109
            PGP GP+G PGLPG                +G+PG  G PG  GP      PG  G KG+
Sbjct: 72   PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161
             G PGL G  G+ GIPG  GL+G KG    E        G  GLPG PGP+G  G  G  
Sbjct: 132  QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221
            G  G  GPPG  G  G  GP+G +G  GE        +++               T PP 
Sbjct: 192  GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239

Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
            P       PGT  +   G  ++  + GE G  G      GEPG  G  G PG+   S +G
Sbjct: 240  P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288



 Score =  121 bits (304), Expect = 4e-27
 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090
            P    G   P        S   PG PGP                  +GPPGLPG  G+PG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123
              G                          PGPRG PG +G KGD G PG  G PG +G  
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157
                                    IPG+ G +GP G RG  G  G PGPPG    G +G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196
             G+ G  G +GPPGT             G  GLPGP+G+         +GEKG P  L +
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256
            +                     PP PI   K  PG    G PGT     +PG  G  G  
Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365

Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276
                GEPG  G+ G PG  G
Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382



 Score =  120 bits (300), Expect = 1e-26
 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106
            GPPG +GPPGLPG  G+PG  G                          PGPRG PG +G 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190

Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164
            KGD G PG  G PG +G  G  G +GP G+ G  G  GLPG   PG  G +G  G+RG+ 
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
            G  GPPG  G + + G KG++G  G P                          + P    
Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285

Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 PG   LG+PGT     +PG  G  G     +G PG  G+ G+PG  G+
Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329



 Score =  120 bits (300), Expect = 1e-26
 Identities = 69/147 (46%), Positives = 78/147 (53%), Gaps = 24/147 (16%)

Query: 1072 GPPGPQGPPGL------PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
            G PGP+GPPG       PGR G PG  G PGPRG PG +G  G  G  G  G  G  G P
Sbjct: 1274 GHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPP 1333

Query: 1126 GRVGLQGPKGMRGLEGT---AGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP------- 1175
            G +G +GP G+RG  GT     LPG PGP G  G  G +G  G  GPPG +GP       
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393

Query: 1176 -----TGLPGP---KGERGEKGEPQSL 1194
                  G PGP   KG +G KGEP+SL
Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEPESL 1420



 Score =  119 bits (298), Expect = 2e-26
 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%)

Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            PA    C C  +      G  G +G  G PG  G+PG++GF GP G PG +G KG  GLP
Sbjct: 25   PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            GL G  G +GI G   L G  G  GL GT G  GP G  G  G +G++G  G  G PGT+
Sbjct: 85   GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G+PG  G +G+KG P                +K D        P  +      PG  
Sbjct: 142  GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192

Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P+G PG       PG  G        G R +  +GE G  G  G PG  G
Sbjct: 193  PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242



 Score =  119 bits (298), Expect = 2e-26
 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118
            PG PGPQGPPG+PG  G  G+ G PGP G PG+ G         KGD G PG +G     
Sbjct: 664  PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723

Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174
               G  G+PG+ GL G KG     + G  G PG PG RG  G  G  G  G  G PGT G
Sbjct: 724  GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783

Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218
              GL GP+G+ G+ G P                Q L  L  L  Q     K     +   
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840

Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260
            P +P L++   PG               PLG    PG       PGE G  G     G  
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280
                  G PG  GQ GSPG  G   Q
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQ 926



 Score =  117 bits (293), Expect = 7e-26
 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%)

Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106
            C+ S   PG PGP GPPG +  R G PG+ G PG  G PG+      KGE          
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              G  GLPGL G  G +GIPGR G  G KG  G  G  GLPG PG  G QG  G +G  G
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            E                RG PG  G  G+PG  G +G  G    LA   +   Q      
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268
                     PP        +PG+   GSPG    A  PG   +G   L+G +G PGA G 
Sbjct: 597  ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638

Query: 1269 MGSPGQQG 1276
             G  G +G
Sbjct: 639  PGEAGPRG 646



 Score =  117 bits (293), Expect = 7e-26
 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%)

Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102
            C+     PGPPG  G PGL                     PG  G PG  GFPG +G PG
Sbjct: 476  CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535

Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158
            +KGEKG+     G  G+ G PG +G PGR GL    G+ G  G  GLPGP G     G  
Sbjct: 536  LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592

Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218
            G +G  G+ G PG+ GP G  GP G  G +GEP    T  Q V  A              
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649

Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274
               P+      PG  P G PG +    +PG  G+ G   L G  GEPG   +G  G PG 
Sbjct: 650  VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 1275 QG 1276
            +G
Sbjct: 708  KG 709



 Score =  116 bits (291), Expect = 1e-25
 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%)

Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114
            S  +PGP GP GPPG      PG  GT G  G PGP G  G +GE        G  G PG
Sbjct: 603  SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662

Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              GHPG QG PG           GL GP G  G+ G  G PGPPGP+G QG  G   T G
Sbjct: 663  PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
              G PG +G  GLPG  G  G KGEP                                + 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274
                PGT   G PG R  +   GE G           G   L+G RG+PG  G  G  G 
Sbjct: 748  MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1275 QGASTQG 1281
             G   +G
Sbjct: 806  PGRCIEG 812



 Score =  116 bits (290), Expect = 2e-25
 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%)

Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125
            G PG    G PG PG  G+PG  G PGP GPPG     KG  GDHGLPG  G PG   IP
Sbjct: 407  GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463

Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
            G   + GPKG  GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TG
Sbjct: 464  G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236
            LPG  G  G +G+P       + +     V          +P    L+    PGT  + G
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578

Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282
             PG + +  + GE G  G   +    G PG  G  G PG       GL
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626



 Score =  115 bits (288), Expect = 3e-25
 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107
            G   P+ +S        PG  G  G PG  G  G PG       +G PGP GPPG +G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166
            G  G P   G PG +GIPG +G  G  G +G  GT G PG  G  G  G+ G +G  GE 
Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
                    GPPG  G  GLPG  G++GE G+P                           P
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274
            P  +     E      GSPG   K    G+ G +G + L G    RG PG  G  GSPG 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 1275 QG 1276
             G
Sbjct: 1151 MG 1152



 Score =  113 bits (283), Expect = 1e-24
 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%)

Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099
            PGPPG QGPPG           LPG NG  G+QG                    FPG  G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144
             PG+ G +G+ G  G +G+PG+ GI               PG +G  GP G  G  G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189
             PG PG +G +G  GA+G  G++G                PG  G  G PG KG RG  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
             P  L  L  L   A              P  P L + +      +G PG++ K    G 
Sbjct: 977  MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
             GR GR     G PG  G  G  G+ G S
Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059



 Score =  113 bits (282), Expect = 1e-24
 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122
            G PG  G PG PG  G  G +GFPG  G  G+KG+KGD G PG +G           G +
Sbjct: 297  GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175
            G PG  G +G +G +G  G  G+PG PG      RG  G  G +G+ GERG PG   +G 
Sbjct: 357  GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G PG  G  G  G P                           PP  I+ +K  PG    
Sbjct: 417  PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451

Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278
            G PG      +PG  G  G          ++ G     G PG  G  G PG+QGA+
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507



 Score =  112 bits (281), Expect = 2e-24
 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%)

Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116
            PG PGPQG   PPG PG  G PG  GF       GPRGP G  GE     KG+ G+ GL 
Sbjct: 176  PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235

Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165
            G PG  G    V L GP      KG +G +G  G PGPPGP G  G +     GA G  G
Sbjct: 236  GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
             +G PG  G  G PG +G +G +G P  +              K D      R P    +
Sbjct: 295  LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
               E G E  G+PG       PG  G        RG  G  G  G PG  G+S  GL
Sbjct: 349  TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390



 Score =  112 bits (281), Expect = 2e-24
 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%)

Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085
            TPGPPGP+         GPPG+PG                                    
Sbjct: 358  TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136
                  G+PG  G PGP GPPG     KG  GDHGLPG  G P   GIP   G+ GPKG 
Sbjct: 418  GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471

Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
             GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TGLPG  G  G +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247
            G+P       + +     V           P  P L  + +PG + L G PGT     +P
Sbjct: 532  GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580

Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276
            G   +G   L G +G+ G  G  GSPG  G
Sbjct: 581  GP--KGELALSGEKGDQGPPGDPGSPGSPG 608



 Score =  107 bits (268), Expect = 6e-23
 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102
            PG PGP GPPG PG  G PG                        +G  GP GPPG     
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142
                     +KGEKGD G  G  G PG  G+PG             GLQG  G  G+ G 
Sbjct: 248  LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187
             G  G  G RGF G+ G  G  G++   GPPG  GPT            G PGP G RG 
Sbjct: 308  PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247
            +G PQ                       +  P +P       PG    G+PG        
Sbjct: 368  RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403

Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276
            GE GR G+   G  G PG  G  G PG  G
Sbjct: 404  GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433



 Score =  102 bits (255), Expect = 2e-21
 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%)

Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102
            G T P   V    CS    G  G QG PGLPG     G PG  G  G +G P        
Sbjct: 112  GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167

Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156
              KG+ G  G PG QG PG  G PG VG  GP G  G  G  G  GP G       G +G
Sbjct: 168  DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227

Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
              G +G +G  GPPGTV     GP   T L G KG++G  GEP                 
Sbjct: 228  ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274

Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267
                   +  P      +K  PG   L G PG       PG  G  G     RG PG +G
Sbjct: 275  ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324

Query: 1268 QMGSPGQQG 1276
            + G  GQ+G
Sbjct: 325  EDGIKGQKG 333


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  142 bits (358), Expect = 2e-33
 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122
            GPPGP G PG PG+ G+PG  G  G RG PG KGE+GD G PG          +G PG +
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G    PG  G +G  GM GL+G  GLP   GPPGPRG  G  G  G  G RG PG++G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
            G+PG KG+RG  G P       L  ++ L            + E TRP  P         
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067

Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
              P G PG        GE G+ G   HL   G  GA G  GSPG  G
Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113



 Score =  138 bits (347), Expect = 4e-32
 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            PGPPGP G PGLPG  G  GE G P      GP GP G  G  G  GLPG  G  G  G 
Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177
             G  GL GP G+RG  G  G PG PGP   RG QG  G  G +GE+G  G +    GP G
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236
             PG +G +G++G P       +  +      +  +  E   P  P L   + PG T   G
Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242

Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282
             PG+R     PG  G  G H+ G             +G PG  G MG PG+ GA  T GL
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302



 Score =  135 bits (340), Expect = 3e-31
 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%)

Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126
            PGPPG  G   PG  G  G PG +G PG  GPPG  G    G  G  G  GHPG +G PG
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  GT GLPGP G  GFQG  G +G  G  G  G++GP G  GPKG  G
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
             +G+P +L  +    S     +  +        PP P     L P   P G PG   K  
Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PG  G  G +   +GEPG  G  G PG +G
Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430



 Score =  127 bits (320), Expect = 5e-29
 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%)

Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107
            S S+  PGPPGP GPPG PG  G P         G+ G PGP G PG+         G K
Sbjct: 649  SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159
            GD G PG +      G  G  G+PG+ GL G KG     + G  G PG PG RG  G  G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203
              G  G  G PGT G  GL GP+G+ G+ G P                Q L  L  L  Q
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828

Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263
                 K     +   P +P L++   PG    GSPG      +PG  G  G  L  RG P
Sbjct: 829  QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876

Query: 1264 GAVGQMGSPGQQG 1276
            G  G +G PG+ G
Sbjct: 877  GNPGILGPPGEDG 889



 Score =  123 bits (309), Expect = 1e-27
 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%)

Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109
            PGP GP+G PGLPG                +G+PG  G PG  GP      PG  G KG+
Sbjct: 72   PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161
             G PGL G  G+ GIPG  GL+G KG    E        G  GLPG PGP+G  G  G  
Sbjct: 132  QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221
            G  G  GPPG  G  G  GP+G +G  GE        +++               T PP 
Sbjct: 192  GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239

Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
            P       PGT  +   G  ++  + GE G  G      GEPG  G  G PG+   S +G
Sbjct: 240  P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288



 Score =  121 bits (304), Expect = 4e-27
 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090
            P    G   P        S   PG PGP                  +GPPGLPG  G+PG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123
              G                          PGPRG PG +G KGD G PG  G PG +G  
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157
                                    IPG+ G +GP G RG  G  G PGPPG    G +G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196
             G+ G  G +GPPGT             G  GLPGP+G+         +GEKG P  L +
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256
            +                     PP PI   K  PG    G PGT     +PG  G  G  
Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365

Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276
                GEPG  G+ G PG  G
Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382



 Score =  120 bits (300), Expect = 1e-26
 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106
            GPPG +GPPGLPG  G+PG  G                          PGPRG PG +G 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190

Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164
            KGD G PG  G PG +G  G  G +GP G+ G  G  GLPG   PG  G +G  G+RG+ 
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
            G  GPPG  G + + G KG++G  G P                          + P    
Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285

Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 PG   LG+PGT     +PG  G  G     +G PG  G+ G+PG  G+
Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329



 Score =  119 bits (299), Expect = 1e-26
 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117
            TPG PGP+G PG  G  G  GE+G P            GP+GPPGV+G+ G   +  L G
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358

Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171
             PG  G PG  G+Q      GP G  G  G  G PG  G  G  G AG +G  G +G PG
Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
              G  GLPG KG+RG+ G P +  T   + ++ S  +   S  E T P
Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466



 Score =  119 bits (298), Expect = 2e-26
 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%)

Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            PA    C C  +      G  G +G  G PG  G+PG++GF GP G PG +G KG  GLP
Sbjct: 25   PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            GL G  G +GI G   L G  G  GL GT G  GP G  G  G +G++G  G  G PGT+
Sbjct: 85   GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G+PG  G +G+KG P                +K D        P  +      PG  
Sbjct: 142  GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192

Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P+G PG       PG  G        G R +  +GE G  G  G PG  G
Sbjct: 193  PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242



 Score =  119 bits (298), Expect = 2e-26
 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118
            PG PGPQGPPG+PG  G  G+ G PGP G PG+ G         KGD G PG +G     
Sbjct: 664  PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723

Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174
               G  G+PG+ GL G KG     + G  G PG PG RG  G  G  G  G  G PGT G
Sbjct: 724  GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783

Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218
              GL GP+G+ G+ G P                Q L  L  L  Q     K     +   
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840

Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260
            P +P L++   PG               PLG    PG       PGE G  G     G  
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280
                  G PG  GQ GSPG  G   Q
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQ 926



 Score =  117 bits (293), Expect = 7e-26
 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%)

Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106
            C+ S   PG PGP GPPG +  R G PG+ G PG  G PG+      KGE          
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              G  GLPGL G  G +GIPGR G  G KG  G  G  GLPG PG  G QG  G +G  G
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            E                RG PG  G  G+PG  G +G  G    LA   +   Q      
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268
                     PP        +PG+   GSPG    A  PG   +G   L+G +G PGA G 
Sbjct: 597  ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638

Query: 1269 MGSPGQQG 1276
             G  G +G
Sbjct: 639  PGEAGPRG 646



 Score =  117 bits (293), Expect = 7e-26
 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%)

Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102
            C+     PGPPG  G PGL                     PG  G PG  GFPG +G PG
Sbjct: 476  CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535

Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158
            +KGEKG+     G  G+ G PG +G PGR GL    G+ G  G  GLPGP G     G  
Sbjct: 536  LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592

Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218
            G +G  G+ G PG+ GP G  GP G  G +GEP    T  Q V  A              
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649

Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274
               P+      PG  P G PG +    +PG  G+ G   L G  GEPG   +G  G PG 
Sbjct: 650  VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 1275 QG 1276
            +G
Sbjct: 708  KG 709



 Score =  116 bits (291), Expect = 1e-25
 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%)

Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114
            S  +PGP GP GPPG      PG  GT G  G PGP G  G +GE        G  G PG
Sbjct: 603  SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662

Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              GHPG QG PG           GL GP G  G+ G  G PGPPGP+G QG  G   T G
Sbjct: 663  PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
              G PG +G  GLPG  G  G KGEP                                + 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274
                PGT   G PG R  +   GE G           G   L+G RG+PG  G  G  G 
Sbjct: 748  MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1275 QGASTQG 1281
             G   +G
Sbjct: 806  PGRCIEG 812



 Score =  116 bits (290), Expect = 2e-25
 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%)

Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125
            G PG    G PG PG  G+PG  G PGP GPPG     KG  GDHGLPG  G PG   IP
Sbjct: 407  GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463

Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
            G   + GPKG  GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TG
Sbjct: 464  G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236
            LPG  G  G +G+P       + +     V          +P    L+    PGT  + G
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578

Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282
             PG + +  + GE G  G   +    G PG  G  G PG       GL
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626



 Score =  115 bits (288), Expect = 3e-25
 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107
            G   P+ +S        PG  G  G PG  G  G PG       +G PGP GPPG +G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166
            G  G P   G PG +GIPG +G  G  G +G  GT G PG  G  G  G+ G +G  GE 
Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
                    GPPG  G  GLPG  G++GE G+P                           P
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274
            P  +     E      GSPG   K    G+ G +G + L G    RG PG  G  GSPG 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 1275 QG 1276
             G
Sbjct: 1151 MG 1152



 Score =  113 bits (283), Expect = 1e-24
 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%)

Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099
            PGPPG QGPPG           LPG NG  G+QG                    FPG  G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144
             PG+ G +G+ G  G +G+PG+ GI               PG +G  GP G  G  G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189
             PG PG +G +G  GA+G  G++G                PG  G  G PG KG RG  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
             P  L  L  L   A              P  P L + +      +G PG++ K    G 
Sbjct: 977  MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
             GR GR     G PG  G  G  G+ G S
Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059



 Score =  113 bits (282), Expect = 1e-24
 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122
            G PG  G PG PG  G  G +GFPG  G  G+KG+KGD G PG +G           G +
Sbjct: 297  GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175
            G PG  G +G +G +G  G  G+PG PG      RG  G  G +G+ GERG PG   +G 
Sbjct: 357  GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G PG  G  G  G P                           PP  I+ +K  PG    
Sbjct: 417  PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451

Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278
            G PG      +PG  G  G          ++ G     G PG  G  G PG+QGA+
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507



 Score =  112 bits (281), Expect = 2e-24
 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%)

Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116
            PG PGPQG   PPG PG  G PG  GF       GPRGP G  GE     KG+ G+ GL 
Sbjct: 176  PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235

Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165
            G PG  G    V L GP      KG +G +G  G PGPPGP G  G +     GA G  G
Sbjct: 236  GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
             +G PG  G  G PG +G +G +G P  +              K D      R P    +
Sbjct: 295  LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
               E G E  G+PG       PG  G        RG  G  G  G PG  G+S  GL
Sbjct: 349  TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390



 Score =  112 bits (281), Expect = 2e-24
 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%)

Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085
            TPGPPGP+         GPPG+PG                                    
Sbjct: 358  TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136
                  G+PG  G PGP GPPG     KG  GDHGLPG  G P   GIP   G+ GPKG 
Sbjct: 418  GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471

Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
             GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TGLPG  G  G +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247
            G+P       + +     V           P  P L  + +PG + L G PGT     +P
Sbjct: 532  GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580

Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276
            G   +G   L G +G+ G  G  GSPG  G
Sbjct: 581  GP--KGELALSGEKGDQGPPGDPGSPGSPG 608



 Score =  107 bits (268), Expect = 6e-23
 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102
            PG PGP GPPG PG  G PG                        +G  GP GPPG     
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142
                     +KGEKGD G  G  G PG  G+PG             GLQG  G  G+ G 
Sbjct: 248  LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187
             G  G  G RGF G+ G  G  G++   GPPG  GPT            G PGP G RG 
Sbjct: 308  PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247
            +G PQ                       +  P +P       PG    G+PG        
Sbjct: 368  RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403

Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276
            GE GR G+   G  G PG  G  G PG  G
Sbjct: 404  GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433



 Score =  102 bits (255), Expect = 2e-21
 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%)

Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102
            G T P   V    CS    G  G QG PGLPG     G PG  G  G +G P        
Sbjct: 112  GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167

Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156
              KG+ G  G PG QG PG  G PG VG  GP G  G  G  G  GP G       G +G
Sbjct: 168  DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227

Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
              G +G +G  GPPGTV     GP   T L G KG++G  GEP                 
Sbjct: 228  ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274

Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267
                   +  P      +K  PG   L G PG       PG  G  G     RG PG +G
Sbjct: 275  ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324

Query: 1268 QMGSPGQQG 1276
            + G  GQ+G
Sbjct: 325  EDGIKGQKG 333


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  142 bits (358), Expect = 2e-33
 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122
            GPPGP G PG PG+ G+PG  G  G RG PG KGE+GD G PG          +G PG +
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G    PG  G +G  GM GL+G  GLP   GPPGPRG  G  G  G  G RG PG++G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
            G+PG KG+RG  G P       L  ++ L            + E TRP  P         
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067

Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
              P G PG        GE G+ G   HL   G  GA G  GSPG  G
Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113



 Score =  138 bits (347), Expect = 4e-32
 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            PGPPGP G PGLPG  G  GE G P      GP GP G  G  G  GLPG  G  G  G 
Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177
             G  GL GP G+RG  G  G PG PGP   RG QG  G  G +GE+G  G +    GP G
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236
             PG +G +G++G P       +  +      +  +  E   P  P L   + PG T   G
Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242

Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282
             PG+R     PG  G  G H+ G             +G PG  G MG PG+ GA  T GL
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302



 Score =  135 bits (340), Expect = 3e-31
 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%)

Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126
            PGPPG  G   PG  G  G PG +G PG  GPPG  G    G  G  G  GHPG +G PG
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  GT GLPGP G  GFQG  G +G  G  G  G++GP G  GPKG  G
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
             +G+P +L  +    S     +  +        PP P     L P   P G PG   K  
Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PG  G  G +   +GEPG  G  G PG +G
Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430



 Score =  127 bits (320), Expect = 5e-29
 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%)

Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107
            S S+  PGPPGP GPPG PG  G P         G+ G PGP G PG+         G K
Sbjct: 649  SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159
            GD G PG +      G  G  G+PG+ GL G KG     + G  G PG PG RG  G  G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203
              G  G  G PGT G  GL GP+G+ G+ G P                Q L  L  L  Q
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828

Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263
                 K     +   P +P L++   PG    GSPG      +PG  G  G  L  RG P
Sbjct: 829  QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876

Query: 1264 GAVGQMGSPGQQG 1276
            G  G +G PG+ G
Sbjct: 877  GNPGILGPPGEDG 889



 Score =  123 bits (309), Expect = 1e-27
 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%)

Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109
            PGP GP+G PGLPG                +G+PG  G PG  GP      PG  G KG+
Sbjct: 72   PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161
             G PGL G  G+ GIPG  GL+G KG    E        G  GLPG PGP+G  G  G  
Sbjct: 132  QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221
            G  G  GPPG  G  G  GP+G +G  GE        +++               T PP 
Sbjct: 192  GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239

Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
            P       PGT  +   G  ++  + GE G  G      GEPG  G  G PG+   S +G
Sbjct: 240  P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288



 Score =  121 bits (304), Expect = 4e-27
 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090
            P    G   P        S   PG PGP                  +GPPGLPG  G+PG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123
              G                          PGPRG PG +G KGD G PG  G PG +G  
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157
                                    IPG+ G +GP G RG  G  G PGPPG    G +G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196
             G+ G  G +GPPGT             G  GLPGP+G+         +GEKG P  L +
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256
            +                     PP PI   K  PG    G PGT     +PG  G  G  
Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365

Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276
                GEPG  G+ G PG  G
Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382



 Score =  120 bits (300), Expect = 1e-26
 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106
            GPPG +GPPGLPG  G+PG  G                          PGPRG PG +G 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190

Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164
            KGD G PG  G PG +G  G  G +GP G+ G  G  GLPG   PG  G +G  G+RG+ 
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
            G  GPPG  G + + G KG++G  G P                          + P    
Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285

Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 PG   LG+PGT     +PG  G  G     +G PG  G+ G+PG  G+
Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329



 Score =  119 bits (299), Expect = 1e-26
 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117
            TPG PGP+G PG  G  G  GE+G P            GP+GPPGV+G+ G   +  L G
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358

Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171
             PG  G PG  G+Q      GP G  G  G  G PG  G  G  G AG +G  G +G PG
Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
              G  GLPG KG+RG+ G P +  T   + ++ S  +   S  E T P
Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466



 Score =  119 bits (298), Expect = 2e-26
 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%)

Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            PA    C C  +      G  G +G  G PG  G+PG++GF GP G PG +G KG  GLP
Sbjct: 25   PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            GL G  G +GI G   L G  G  GL GT G  GP G  G  G +G++G  G  G PGT+
Sbjct: 85   GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G+PG  G +G+KG P                +K D        P  +      PG  
Sbjct: 142  GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192

Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P+G PG       PG  G        G R +  +GE G  G  G PG  G
Sbjct: 193  PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242



 Score =  119 bits (298), Expect = 2e-26
 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118
            PG PGPQGPPG+PG  G  G+ G PGP G PG+ G         KGD G PG +G     
Sbjct: 664  PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723

Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174
               G  G+PG+ GL G KG     + G  G PG PG RG  G  G  G  G  G PGT G
Sbjct: 724  GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783

Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218
              GL GP+G+ G+ G P                Q L  L  L  Q     K     +   
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840

Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260
            P +P L++   PG               PLG    PG       PGE G  G     G  
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280
                  G PG  GQ GSPG  G   Q
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQ 926



 Score =  117 bits (293), Expect = 7e-26
 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%)

Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106
            C+ S   PG PGP GPPG +  R G PG+ G PG  G PG+      KGE          
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              G  GLPGL G  G +GIPGR G  G KG  G  G  GLPG PG  G QG  G +G  G
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            E                RG PG  G  G+PG  G +G  G    LA   +   Q      
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268
                     PP        +PG+   GSPG    A  PG   +G   L+G +G PGA G 
Sbjct: 597  ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638

Query: 1269 MGSPGQQG 1276
             G  G +G
Sbjct: 639  PGEAGPRG 646



 Score =  117 bits (293), Expect = 7e-26
 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%)

Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102
            C+     PGPPG  G PGL                     PG  G PG  GFPG +G PG
Sbjct: 476  CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535

Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158
            +KGEKG+     G  G+ G PG +G PGR GL    G+ G  G  GLPGP G     G  
Sbjct: 536  LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592

Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218
            G +G  G+ G PG+ GP G  GP G  G +GEP    T  Q V  A              
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649

Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274
               P+      PG  P G PG +    +PG  G+ G   L G  GEPG   +G  G PG 
Sbjct: 650  VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 1275 QG 1276
            +G
Sbjct: 708  KG 709



 Score =  116 bits (291), Expect = 1e-25
 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%)

Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114
            S  +PGP GP GPPG      PG  GT G  G PGP G  G +GE        G  G PG
Sbjct: 603  SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662

Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              GHPG QG PG           GL GP G  G+ G  G PGPPGP+G QG  G   T G
Sbjct: 663  PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
              G PG +G  GLPG  G  G KGEP                                + 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274
                PGT   G PG R  +   GE G           G   L+G RG+PG  G  G  G 
Sbjct: 748  MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1275 QGASTQG 1281
             G   +G
Sbjct: 806  PGRCIEG 812



 Score =  116 bits (290), Expect = 2e-25
 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%)

Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125
            G PG    G PG PG  G+PG  G PGP GPPG     KG  GDHGLPG  G PG   IP
Sbjct: 407  GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463

Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
            G   + GPKG  GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TG
Sbjct: 464  G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236
            LPG  G  G +G+P       + +     V          +P    L+    PGT  + G
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578

Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282
             PG + +  + GE G  G   +    G PG  G  G PG       GL
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626



 Score =  115 bits (288), Expect = 3e-25
 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107
            G   P+ +S        PG  G  G PG  G  G PG       +G PGP GPPG +G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166
            G  G P   G PG +GIPG +G  G  G +G  GT G PG  G  G  G+ G +G  GE 
Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
                    GPPG  G  GLPG  G++GE G+P                           P
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274
            P  +     E      GSPG   K    G+ G +G + L G    RG PG  G  GSPG 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 1275 QG 1276
             G
Sbjct: 1151 MG 1152



 Score =  113 bits (283), Expect = 1e-24
 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%)

Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099
            PGPPG QGPPG           LPG NG  G+QG                    FPG  G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144
             PG+ G +G+ G  G +G+PG+ GI               PG +G  GP G  G  G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189
             PG PG +G +G  GA+G  G++G                PG  G  G PG KG RG  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
             P  L  L  L   A              P  P L + +      +G PG++ K    G 
Sbjct: 977  MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
             GR GR     G PG  G  G  G+ G S
Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059



 Score =  113 bits (282), Expect = 1e-24
 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122
            G PG  G PG PG  G  G +GFPG  G  G+KG+KGD G PG +G           G +
Sbjct: 297  GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175
            G PG  G +G +G +G  G  G+PG PG      RG  G  G +G+ GERG PG   +G 
Sbjct: 357  GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G PG  G  G  G P                           PP  I+ +K  PG    
Sbjct: 417  PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451

Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278
            G PG      +PG  G  G          ++ G     G PG  G  G PG+QGA+
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507



 Score =  112 bits (281), Expect = 2e-24
 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%)

Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116
            PG PGPQG   PPG PG  G PG  GF       GPRGP G  GE     KG+ G+ GL 
Sbjct: 176  PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235

Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165
            G PG  G    V L GP      KG +G +G  G PGPPGP G  G +     GA G  G
Sbjct: 236  GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
             +G PG  G  G PG +G +G +G P  +              K D      R P    +
Sbjct: 295  LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
               E G E  G+PG       PG  G        RG  G  G  G PG  G+S  GL
Sbjct: 349  TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390



 Score =  112 bits (281), Expect = 2e-24
 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%)

Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085
            TPGPPGP+         GPPG+PG                                    
Sbjct: 358  TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136
                  G+PG  G PGP GPPG     KG  GDHGLPG  G P   GIP   G+ GPKG 
Sbjct: 418  GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471

Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
             GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TGLPG  G  G +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247
            G+P       + +     V           P  P L  + +PG + L G PGT     +P
Sbjct: 532  GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580

Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276
            G   +G   L G +G+ G  G  GSPG  G
Sbjct: 581  GP--KGELALSGEKGDQGPPGDPGSPGSPG 608



 Score =  107 bits (268), Expect = 6e-23
 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102
            PG PGP GPPG PG  G PG                        +G  GP GPPG     
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142
                     +KGEKGD G  G  G PG  G+PG             GLQG  G  G+ G 
Sbjct: 248  LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187
             G  G  G RGF G+ G  G  G++   GPPG  GPT            G PGP G RG 
Sbjct: 308  PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247
            +G PQ                       +  P +P       PG    G+PG        
Sbjct: 368  RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403

Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276
            GE GR G+   G  G PG  G  G PG  G
Sbjct: 404  GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433



 Score =  102 bits (255), Expect = 2e-21
 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%)

Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102
            G T P   V    CS    G  G QG PGLPG     G PG  G  G +G P        
Sbjct: 112  GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167

Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156
              KG+ G  G PG QG PG  G PG VG  GP G  G  G  G  GP G       G +G
Sbjct: 168  DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227

Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
              G +G +G  GPPGTV     GP   T L G KG++G  GEP                 
Sbjct: 228  ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274

Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267
                   +  P      +K  PG   L G PG       PG  G  G     RG PG +G
Sbjct: 275  ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324

Query: 1268 QMGSPGQQG 1276
            + G  GQ+G
Sbjct: 325  EDGIKGQKG 333


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  142 bits (358), Expect = 2e-33
 Identities = 94/227 (41%), Positives = 109/227 (48%), Gaps = 36/227 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL---------QGHPGHQ 1122
            GPPGP G PG PG+ G+PG  G  G RG PG KGE+GD G PG          +G PG +
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 1123 GI---PGRVGLQGPKGMRGLEGTAGLP---GPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G    PG  G +G  GM GL+G  GLP   GPPGPRG  G  G  G  G RG PG++G  
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020

Query: 1177 GLPGPKGERGEKGEP-----QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
            G+PG KG+RG  G P       L  ++ L            + E TRP  P         
Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE----PGYSEGTRPGPP--------- 1067

Query: 1232 TEPLGSPGTRSKALVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
              P G PG        GE G+ G   HL   G  GA G  GSPG  G
Sbjct: 1068 -GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPG 1113



 Score =  138 bits (347), Expect = 4e-32
 Identities = 95/240 (39%), Positives = 112/240 (46%), Gaps = 29/240 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP------GPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            PGPPGP G PGLPG  G  GE G P      GP GP G  G  G  GLPG  G  G  G 
Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123

Query: 1125 PGRVGLQGPKGMRGLEGTAGLPGPPGP---RGFQGMAGARGTSGERGPPGTV----GPTG 1177
             G  GL GP G+RG  G  G PG PGP   RG QG  G  G +GE+G  G +    GP G
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLG 1236
             PG +G +G++G P       +  +      +  +  E   P  P L   + PG T   G
Sbjct: 1184 NPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRG 1242

Query: 1237 SPGTRSKALVPGEWGRGGRHLEG-------------RGEPGAVGQMGSPGQQGA-STQGL 1282
             PG+R     PG  G  G H+ G             +G PG  G MG PG+ GA  T GL
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302



 Score =  135 bits (340), Expect = 3e-31
 Identities = 87/211 (41%), Positives = 101/211 (47%), Gaps = 9/211 (4%)

Query: 1071 PGPPGPQGP--PGLPGRNGTPGEQGFPGPRGPPGVKGEK--GDHGLPGLQGHPGHQGIPG 1126
            PGPPG  G   PG  G  G PG +G PG  GPPG  G    G  G  G  GHPG +G PG
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  GT GLPGP G  GFQG  G +G  G  G  G++GP G  GPKG  G
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFD-SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
             +G+P +L  +    S     +  +        PP P     L P   P G PG   K  
Sbjct: 1344 VRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP--PGNLGP-CGPRGKPGKDGKPG 1400

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             PG  G  G +   +GEPG  G  G PG +G
Sbjct: 1401 TPGPAGEKG-NKGSKGEPGPAGSDGLPGLKG 1430



 Score =  127 bits (320), Expect = 5e-29
 Identities = 95/253 (37%), Positives = 112/253 (44%), Gaps = 53/253 (20%)

Query: 1065 SCSSETPGPPGPQGPPGLPGRNGTP---------GEQGFPGPRGPPGV--------KGEK 1107
            S S+  PGPPGP GPPG PG  G P         G+ G PGP G PG+         G K
Sbjct: 649  SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 1108 GDHGLPGLQ------GHPGHQGIPGRVGLQGPKG--MRGLEGTAGLPGPPGPRGFQGMAG 1159
            GD G PG +      G  G  G+PG+ GL G KG     + G  G PG PG RG  G  G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEP----------------QSLATLYQLVSQ 1203
              G  G  G PGT G  GL GP+G+ G+ G P                Q L  L  L  Q
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQ 828

Query: 1204 ASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP 1263
                 K     +   P +P L++   PG    GSPG      +PG  G  G  L  RG P
Sbjct: 829  QGRRGKTGPKGD---PGIPGLDRSGFPG--ETGSPG------IPGHQGEMG-PLGQRGYP 876

Query: 1264 GAVGQMGSPGQQG 1276
            G  G +G PG+ G
Sbjct: 877  GNPGILGPPGEDG 889



 Score =  123 bits (309), Expect = 1e-27
 Identities = 87/240 (36%), Positives = 105/240 (43%), Gaps = 52/240 (21%)

Query: 1071 PGPPGPQGPPGLPGR---------------NGTPGEQGFPGPRGP------PGVKGEKGD 1109
            PGP GP+G PGLPG                +G+PG  G PG  GP      PG  G KG+
Sbjct: 72   PGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGE 131

Query: 1110 HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLE--------GTAGLPGPPGPRGFQGMAGAR 1161
             G PGL G  G+ GIPG  GL+G KG    E        G  GLPG PGP+G  G  G  
Sbjct: 132  QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP 191

Query: 1162 GTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPM 1221
            G  G  GPPG  G  G  GP+G +G  GE        +++               T PP 
Sbjct: 192  GPVGPPGPPGFFGFPGAMGPRGPKGHMGE--------RVIGHKGE----RGVKGLTGPPG 239

Query: 1222 PILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
            P       PGT  +   G  ++  + GE G  G      GEPG  G  G PG+   S +G
Sbjct: 240  P-------PGTVIVTLTGPDNRTDLKGEKGDKG----AMGEPGPPGPSGLPGESYGSEKG 288



 Score =  121 bits (304), Expect = 4e-27
 Identities = 101/320 (31%), Positives = 117/320 (36%), Gaps = 119/320 (37%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGP------------------QGPPGLPGRNGTPG 1090
            P    G   P        S   PG PGP                  +GPPGLPG  G+PG
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 1091 EQGF-------------------------PGPRGPPGVKGEKGDHGLPGLQGHPGHQG-- 1123
              G                          PGPRG PG +G KGD G PG  G PG +G  
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 1124 ------------------------IPGRVGLQGPKGMRGLEGTAGLPGPPGPR--GFQGM 1157
                                    IPG+ G +GP G RG  G  G PGPPG    G +G 
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGD 1269

Query: 1158 AGARGTSGERGPPGTV------------GPTGLPGPKGE---------RGEKGEPQSLAT 1196
             G+ G  G +GPPGT             G  GLPGP+G+         +GEKG P  L +
Sbjct: 1270 KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 1197 LYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH 1256
            +                     PP PI   K  PG    G PGT     +PG  G  G  
Sbjct: 1330 I--------------------GPPGPI-GPKGPPGVR--GDPGTLKIISLPGSPGPPGT- 1365

Query: 1257 LEGRGEPGAVGQMGSPGQQG 1276
                GEPG  G+ G PG  G
Sbjct: 1366 ---PGEPGMQGEPGPPGPPG 1382



 Score =  120 bits (300), Expect = 1e-26
 Identities = 83/233 (35%), Positives = 103/233 (44%), Gaps = 61/233 (26%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGF-------------------------PGPRGPPGVKGE 1106
            GPPG +GPPGLPG  G+PG  G                          PGPRG PG +G 
Sbjct: 1131 GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGA 1190

Query: 1107 KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGP--PGPRGFQGMAGARGTS 1164
            KGD G PG  G PG +G  G  G +GP G+ G  G  GLPG   PG  G +G  G+RG+ 
Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 1165 GERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPIL 1224
            G  GPPG  G + + G KG++G  G P                          + P    
Sbjct: 1251 GAPGPPGPPG-SHVIGIKGDKGSMGHP------------------------GPKGPPGTA 1285

Query: 1225 EQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 PG   LG+PGT     +PG  G  G     +G PG  G+ G+PG  G+
Sbjct: 1286 GDMGPPGR--LGAPGTPG---LPGPRGDPGF----QGFPGVKGEKGNPGFLGS 1329



 Score =  119 bits (299), Expect = 1e-26
 Identities = 68/168 (40%), Positives = 84/168 (50%), Gaps = 18/168 (10%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFP------------GPRGPPGVKGEKGDHGLPGLQG 1117
            TPG PGP+G PG  G  G  GE+G P            GP+GPPGV+G+ G   +  L G
Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPG 1358

Query: 1118 HPGHQGIPGRVGLQ------GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171
             PG  G PG  G+Q      GP G  G  G  G PG  G  G  G AG +G  G +G PG
Sbjct: 1359 SPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
              G  GLPG KG+RG+ G P +  T   + ++ S  +   S  E T P
Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVP 1466



 Score =  119 bits (298), Expect = 2e-26
 Identities = 84/230 (36%), Positives = 103/230 (44%), Gaps = 23/230 (10%)

Query: 1058 PAFVSACSCSSE----TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            PA    C C  +      G  G +G  G PG  G+PG++GF GP G PG +G KG  GLP
Sbjct: 25   PAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLP 84

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV 1173
            GL G  G +GI G   L G  G  GL GT G  GP G  G  G +G++G  G  G PGT+
Sbjct: 85   GLTGSKGVRGISG---LPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            G  G+PG  G +G+KG P                +K D        P  +      PG  
Sbjct: 142  GYPGIPGAAGLKGQKGAPAK-------EEDIELDAKGDPGLPGAPGPQGLPGPPGFPG-- 192

Query: 1234 PLGSPGTRSKALVPGEWG-------RGGRHLEGRGEPGAVGQMGSPGQQG 1276
            P+G PG       PG  G        G R +  +GE G  G  G PG  G
Sbjct: 193  PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242



 Score =  119 bits (298), Expect = 2e-26
 Identities = 96/266 (36%), Positives = 110/266 (41%), Gaps = 59/266 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG--------EKGDHGLPGLQGH---- 1118
            PG PGPQGPPG+PG  G  G+ G PGP G PG+ G         KGD G PG +G     
Sbjct: 664  PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723

Query: 1119 --PGHQGIPGRVGLQGPKGMRG--LEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG 1174
               G  G+PG+ GL G KG     + G  G PG PG RG  G  G  G  G  G PGT G
Sbjct: 724  GKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPG 783

Query: 1175 PTGLPGPKGERGEKGEP----------------QSLATLYQLVSQASHVSKFDSFHENTR 1218
              GL GP+G+ G+ G P                Q L  L  L  Q     K     +   
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD--- 840

Query: 1219 PPMPILEQKLEPGTE-------------PLGS---PGTRSKALVPGEWGR-GGRHLEGR- 1260
            P +P L++   PG               PLG    PG       PGE G  G     G  
Sbjct: 841  PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900

Query: 1261 ------GEPGAVGQMGSPGQQGASTQ 1280
                  G PG  GQ GSPG  G   Q
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQ 926



 Score =  117 bits (293), Expect = 7e-26
 Identities = 92/248 (37%), Positives = 107/248 (43%), Gaps = 58/248 (23%)

Query: 1064 CSCSSETPGPPGPQGPPG-LPGRNGTPGEQGFPGPRGPPGV------KGE---------- 1106
            C+ S   PG PGP GPPG +  R G PG+ G PG  G PG+      KGE          
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 1107 -KGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              G  GLPGL G  G +GIPGR G  G KG  G  G  GLPG PG  G QG  G +G  G
Sbjct: 482  IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541

Query: 1166 E----------------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            E                RG PG  G  G+PG  G +G  G    LA   +   Q      
Sbjct: 542  ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG----- 596

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEG-RGEPGAVGQ 1268
                     PP        +PG+   GSPG    A  PG   +G   L+G +G PGA G 
Sbjct: 597  ---------PPG-------DPGSP--GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638

Query: 1269 MGSPGQQG 1276
             G  G +G
Sbjct: 639  PGEAGPRG 646



 Score =  117 bits (293), Expect = 7e-26
 Identities = 90/242 (37%), Positives = 107/242 (44%), Gaps = 37/242 (15%)

Query: 1064 CSCSSETPGPPGPQGPPGL---------------------PGRNGTPGEQGFPGPRGPPG 1102
            C+     PGPPG  G PGL                     PG  G PG  GFPG +G PG
Sbjct: 476  CTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPG 535

Query: 1103 VKGEKGD----HGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMA 1158
            +KGEKG+     G  G+ G PG +G PGR GL    G+ G  G  GLPGP G     G  
Sbjct: 536  LKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLD---GIPGTPGVKGLPGPKGELALSGEK 592

Query: 1159 GARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR 1218
            G +G  G+ G PG+ GP G  GP G  G +GEP    T  Q V  A              
Sbjct: 593  GDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGT--QGVPGAPGPPGEAGPRGELS 649

Query: 1219 PPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-GGRHLEG-RGEPG--AVGQMGSPGQ 1274
               P+      PG  P G PG +    +PG  G+ G   L G  GEPG   +G  G PG 
Sbjct: 650  VSTPVPGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 1275 QG 1276
            +G
Sbjct: 708  KG 709



 Score =  116 bits (291), Expect = 1e-25
 Identities = 91/247 (36%), Positives = 101/247 (40%), Gaps = 69/247 (27%)

Query: 1067 SSETPGPPGPQGPPGL-----PGRNGTPGEQGFPGPRGPPGVKGE-------KGDHGLPG 1114
            S  +PGP GP GPPG      PG  GT G  G PGP G  G +GE        G  G PG
Sbjct: 603  SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG 662

Query: 1115 LQGHPGHQGIPG---------RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
              GHPG QG PG           GL GP G  G+ G  G PGPPGP+G QG  G   T G
Sbjct: 663  PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-GFPGPPGPKGDQGFPG---TKG 718

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
              G PG +G  GLPG  G  G KGEP                                + 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPA-------------------------------VA 747

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGR----------GGRHLEG-RGEPGAVGQMGSPGQ 1274
                PGT   G PG R  +   GE G           G   L+G RG+PG  G  G  G 
Sbjct: 748  MPGGPGTP--GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1275 QGASTQG 1281
             G   +G
Sbjct: 806  PGRCIEG 812



 Score =  116 bits (290), Expect = 2e-25
 Identities = 87/228 (38%), Positives = 106/228 (46%), Gaps = 25/228 (10%)

Query: 1072 GPPGPQ--GPPGLPGRNGTPGEQGFPGPRGPPGV----KGEKGDHGLPGLQGHPGHQGIP 1125
            G PG    G PG PG  G+PG  G PGP GPPG     KG  GDHGLPG  G PG   IP
Sbjct: 407  GRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG---IP 463

Query: 1126 GRVGLQGPKGMRGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
            G   + GPKG  GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TG
Sbjct: 464  G---VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG 520

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-G 1236
            LPG  G  G +G+P       + +     V          +P    L+    PGT  + G
Sbjct: 521  LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI--PGTPGVKG 578

Query: 1237 SPGTRSKALVPGEWGRGGRHLE--GRGEPGAVGQMGSPGQQGASTQGL 1282
             PG + +  + GE G  G   +    G PG  G  G PG       GL
Sbjct: 579  LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626



 Score =  115 bits (288), Expect = 3e-25
 Identities = 85/242 (35%), Positives = 102/242 (42%), Gaps = 48/242 (19%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGE------QGFPGPRGPPGVKGEK 1107
            G   P+ +S        PG  G  G PG  G  G PG       +G PGP GPPG +G+ 
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 1108 GDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE- 1166
            G  G P   G PG +GIPG +G  G  G +G  GT G PG  G  G  G+ G +G  GE 
Sbjct: 1000 GSTGNP---GEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1167 -------RGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRP 1219
                    GPPG  G  GLPG  G++GE G+P                           P
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP--------------------------GP 1090

Query: 1220 PMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVGQMGSPGQ 1274
            P  +     E      GSPG   K    G+ G +G + L G    RG PG  G  GSPG 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 1275 QG 1276
             G
Sbjct: 1151 MG 1152



 Score =  113 bits (283), Expect = 1e-24
 Identities = 89/269 (33%), Positives = 108/269 (40%), Gaps = 67/269 (24%)

Query: 1071 PGPPGPQGPPG-----------LPGRNGTPGEQG--------------------FPGPRG 1099
            PGPPG QGPPG           LPG NG  G+QG                    FPG  G
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 1100 PPGVKGEKGDHGLPGLQGHPGHQGI---------------PGRVGLQGPKGMRGLEGTAG 1144
             PG+ G +G+ G  G +G+PG+ GI               PG +G  GP G  G  G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 1145 LPGPPGPRGFQGMAGARGTSGERG---------------PPGTVGPTGLPGPKGERGEKG 1189
             PG PG +G +G  GA+G  G++G                PG  G  G PG KG RG  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 1190 EPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGE 1249
             P  L  L  L   A              P  P L + +      +G PG++ K    G 
Sbjct: 977  MP-GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL-RGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 1250 WGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
             GR GR     G PG  G  G  G+ G S
Sbjct: 1035 PGRAGR----PGLPGIHGLQGDKGEPGYS 1059



 Score =  113 bits (282), Expect = 1e-24
 Identities = 82/236 (34%), Positives = 101/236 (42%), Gaps = 54/236 (22%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQG---------HPGHQ 1122
            G PG  G PG PG  G  G +GFPG  G  G+KG+KGD G PG +G           G +
Sbjct: 297  GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDE 356

Query: 1123 GIPGRVGLQGPKGMRGLEGTAGLPGPPGP-----RGFQGMAGARGTSGERGPPG--TVGP 1175
            G PG  G +G +G +G  G  G+PG PG      RG  G  G +G+ GERG PG   +G 
Sbjct: 357  GTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGT 416

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G PG  G  G  G P                           PP  I+ +K  PG    
Sbjct: 417  PGSPGCAGSPGLPGSPGP-----------------------PGPPGDIVFRKGPPGDH-- 451

Query: 1236 GSPGTRSKALVPGEWGRGGR---------HLEG----RGEPGAVGQMGSPGQQGAS 1278
            G PG      +PG  G  G          ++ G     G PG  G  G PG+QGA+
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507



 Score =  112 bits (281), Expect = 2e-24
 Identities = 90/237 (37%), Positives = 103/237 (43%), Gaps = 47/237 (19%)

Query: 1071 PGPPGPQG---PPGLPGRNGTPGEQGF------PGPRGPPGVKGE-----KGDHGLPGLQ 1116
            PG PGPQG   PPG PG  G PG  GF       GPRGP G  GE     KG+ G+ GL 
Sbjct: 176  PGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235

Query: 1117 GHPGHQGIPGRVGLQGP------KGMRGLEGTAGLPGPPGPRGFQGMA-----GARGTSG 1165
            G PG  G    V L GP      KG +G +G  G PGPPGP G  G +     GA G  G
Sbjct: 236  GPPGPPGTV-IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
             +G PG  G  G PG +G +G +G P  +              K D      R P    +
Sbjct: 295  LQGKPGKDGVPGFPGSEGVKGNRGFPGLMG------EDGIKGQKGDIGPPGFRGPTEYYD 348

Query: 1226 QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
               E G E  G+PG       PG  G        RG  G  G  G PG  G+S  GL
Sbjct: 349  TYQEKGDE--GTPGP------PGPRG-------ARGPQGPSGPPGVPGSPGSSRPGL 390



 Score =  112 bits (281), Expect = 2e-24
 Identities = 94/270 (34%), Positives = 115/270 (42%), Gaps = 82/270 (30%)

Query: 1070 TPGPPGPQ---------GPPGLPGR----------------------------------- 1085
            TPGPPGP+         GPPG+PG                                    
Sbjct: 358  TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 1086 -----NGTPGEQGFPGPRGPPG----VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGM 1136
                  G+PG  G PGP GPPG     KG  GDHGLPG  G P   GIP   G+ GPKG 
Sbjct: 418  GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP---GIP---GVDGPKGE 471

Query: 1137 RGL--------EGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
             GL         G  GLPG PG  G +G+ G +G +G +G PG+ G TGLPG  G  G +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVP 1247
            G+P       + +     V           P  P L  + +PG + L G PGT     +P
Sbjct: 532  GDPGLKGEKGETLQPEGQVGV---------PGDPGL--RGQPGRKGLDGIPGTPGVKGLP 580

Query: 1248 GEWGRGGRHLEG-RGEPGAVGQMGSPGQQG 1276
            G   +G   L G +G+ G  G  GSPG  G
Sbjct: 581  GP--KGELALSGEKGDQGPPGDPGSPGSPG 608



 Score =  107 bits (268), Expect = 6e-23
 Identities = 90/270 (33%), Positives = 102/270 (37%), Gaps = 88/270 (32%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGE-----------------------QGFPGPRGPPG----- 1102
            PG PGP GPPG PG  G PG                        +G  GP GPPG     
Sbjct: 188  PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 1103 ---------VKGEKGDHGLPGLQGHPGHQGIPGR-----------VGLQGPKGMRGLEGT 1142
                     +KGEKGD G  G  G PG  G+PG             GLQG  G  G+ G 
Sbjct: 248  LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF 307

Query: 1143 AGLPGPPGPRGFQGMAGARGTSGER---GPPGTVGPT------------GLPGPKGERGE 1187
             G  G  G RGF G+ G  G  G++   GPPG  GPT            G PGP G RG 
Sbjct: 308  PGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGA 367

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVP 1247
            +G PQ                       +  P +P       PG    G+PG        
Sbjct: 368  RG-PQG---------------------PSGPPGVPGSPGSSRPGLR--GAPGWPGLKGSK 403

Query: 1248 GEWGRGGRHLEGR-GEPGAVGQMGSPGQQG 1276
            GE GR G+   G  G PG  G  G PG  G
Sbjct: 404  GERGRPGKDAMGTPGSPGCAGSPGLPGSPG 433



 Score =  102 bits (255), Expect = 2e-21
 Identities = 89/249 (35%), Positives = 101/249 (40%), Gaps = 53/249 (21%)

Query: 1054 GETCP-AFVSACSCSSETPGPPGPQGPPGLPGR---NGTPGEQGFPGPRGPPG------- 1102
            G T P   V    CS    G  G QG PGLPG     G PG  G  G +G P        
Sbjct: 112  GNTGPYGLVGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL 167

Query: 1103 -VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR-----GFQG 1156
              KG+ G  G PG QG PG  G PG VG  GP G  G  G  G  GP G       G +G
Sbjct: 168  DAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKG 227

Query: 1157 MAGARGTSGERGPPGTV-----GP---TGLPGPKGERGEKGEPQSLATLYQLVSQASHVS 1208
              G +G +G  GPPGTV     GP   T L G KG++G  GEP                 
Sbjct: 228  ERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG------------- 274

Query: 1209 KFDSFHENTRPPMPILEQKLEPGTEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVG 1267
                   +  P      +K  PG   L G PG       PG  G  G     RG PG +G
Sbjct: 275  ------PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG----NRGFPGLMG 324

Query: 1268 QMGSPGQQG 1276
            + G  GQ+G
Sbjct: 325  EDGIKGQKG 333


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  141 bits (356), Expect = 4e-33
 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120
            PGPPGP G  GLPG  G  G +G PGP+G      P G++G  G+ GLPG QG PG    
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173
               QG PG VG  G +G  G  G  GLPG PGP+G  G AG +G  GE+GP G       
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1118

Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             GP GLPGP G  G  GE      + +   + S   K ++      PP P       PG 
Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1166

Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
            + P+G+PG       PG  G+ G   + +G+ GA G  G PG  G   QGL
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1214



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127
            T G  GP GPPG  G  G  G  GFPGP+GPPG  G+ G  G PG +G  G QG  G   
Sbjct: 917  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976

Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183
                VG QGP G  G  G  G PGPPGP G QG+ GA G  G +G PG  G +G  GP G
Sbjct: 977  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036

Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243
             RG  GE        + +  A              PP P+            GSPG R  
Sbjct: 1037 LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1076

Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            A   G  G  GR    +G PG  G+ G+PG++G
Sbjct: 1077 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1108



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGPQGPPG  G  G PGE+G  GP G  GV+G  G  G  G  G PG  G  G +G 
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1145

Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169
             G KG +G +G  G PGPPG                  PRG QGM G +G  G RG   P
Sbjct: 1146 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1205

Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229
            PG +G  GLPGP GE+GE G+   +                        PP P   Q   
Sbjct: 1206 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1245

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                P G PG+       GE          +GEPG  G  G PG+ G
Sbjct: 1246 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1282



 Score =  133 bits (334), Expect = 1e-30
 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%)

Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
            GPPGP G      P G PG +G  GE G PGP+GP GV+G  G  G PG +G PG  G  
Sbjct: 541  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173
            G  G  G KG RG +G  GLPG            PPGP G  GM G  G  G RG PG  
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            GP GL GP+G  G  G+P        +           +      P  P   Q+  PG  
Sbjct: 661  GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 709

Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            P G PG +     PGE G  G+     G PGA G  G PG++G S
Sbjct: 710  PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 753



 Score =  131 bits (329), Expect = 5e-30
 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%)

Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            PGP G   PQG PG PG+ G PG QG PGP+GP G  GEKG  G PGL G PG  G PG 
Sbjct: 687  PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
             G +G  G +G  G  G  GP   PGPRG +G  G RG  G +G  G  G  G  G  G 
Sbjct: 747  PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 806

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244
            +G++GE   +    +               +    P        +PG  P G  G + K 
Sbjct: 807  KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 849

Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             VPG  G  GR    +G  G+ G  G PG  G
Sbjct: 850  GVPGLPGYPGR----QGPKGSTGFPGFPGANG 877



 Score =  131 bits (329), Expect = 5e-30
 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPGP G  GLPG  G  GE G  GP GPPG  G +G  G  G  G    QG PG VG 
Sbjct: 1203 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1259

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G  G +G  G AG PGPPG  G  G  G RG  GE GPPG  GP G  GP G+ G KG 
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242
            P  +               F         P P  +  +        +PG    G PG   
Sbjct: 1320 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1363

Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            +A  PG  G+       RG PGA G  G  G++GA
Sbjct: 1364 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1391



 Score =  131 bits (329), Expect = 5e-30
 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPG +GPPG  G  G PG  GFPG  GPPG  G  G  G+ G +G  G  G PG  G  
Sbjct: 1303 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1362

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G  G  G  G  G PG  G  G QG  GA+G +G  GPPG  GP G  GP G+ G    P
Sbjct: 1363 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1418

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251
            + L  +                      P P+ EQ L       G PG      +PG  G
Sbjct: 1419 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1456

Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G   E +G PG +G +G PG+QG
Sbjct: 1457 DPGSKGE-KGHPGLIGLIGPPGEQG 1480



 Score =  130 bits (327), Expect = 8e-30
 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%)

Query: 997  GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056
            GE GS   AG + L      +GP   +             +  A  ++  + PA RDG  
Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1119

Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116
             P  +   +  + +PG  G +G  G PG+ G+ G++G  GP GPPG++G  G  G+ G  
Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1179

Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G PG +      G QG  G +G EG  G PGPPGP G QG+ G  G  GE G  G +GP 
Sbjct: 1180 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233

Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229
            G PGP+G +G  G   PQ                          PP  +     + +K E
Sbjct: 1234 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1268

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            PG    G+PG   +A V G  G  G   E  G PGA G  G+ G  G
Sbjct: 1269 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1312



 Score =  122 bits (305), Expect = 3e-27
 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P GE G P   G          RGP  ++ A   Q       +  A  +   E P  + G
Sbjct: 1361 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1405

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
               P   +         G PGP G  GLP   G  G+ G PGP GPPG+ G KGD G  G
Sbjct: 1406 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1462

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159
             +GHPG  G+ G  G QG KG RGL GT G P               GPPGP G  G  G
Sbjct: 1463 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1522

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             +G  G  GP G  G +GLPGP G  G  GE
Sbjct: 1523 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553



 Score =  120 bits (302), Expect = 6e-27
 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128
            G PGP G  G  G+ G PG  G+PG +GP   KG  G  G PG  G  G +G+   PG  
Sbjct: 835  GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 891

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G +GP G RG  G  G  G PGP+G  G  G  G  GERGP G  GP G PGPKG  G  
Sbjct: 892  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 951

Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243
            G+               H  +     F   T PP P   +  Q     T P+G  G    
Sbjct: 952  GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001

Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
               PGE G  G    EG +G+PG  G  G  G  G
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036



 Score =  120 bits (300), Expect = 1e-26
 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%)

Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115
            S     S  PGP GP   QGPPG    PG+ G PG  G  G  G PG KG++G  GLPGL
Sbjct: 561  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 620

Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151
             G  GH+G          PG  G++G               P+G+ G  GT G PG PG 
Sbjct: 621  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680

Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199
             G  G  G +G     GE GPP   G  GP GLPGP+      GE+G +G+P  LA L  
Sbjct: 681  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 739

Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256
                  H  K     E     PP P           P+G PG R      G  G +G + 
Sbjct: 740  ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 790

Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276
             +G  G PG  G MG  G +G
Sbjct: 791  EKGEDGFPGFKGDMGLKGDRG 811



 Score =  120 bits (300), Expect = 1e-26
 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G  GP G  G  G  G  G  G  GP G  GEKG  G+PGL G+PG QG  G  G  
Sbjct: 811  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185
            G  G  G +G  G+ G PGPRG +G  G RG+ G RGP G  GP G       PGP GER
Sbjct: 871  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G PQ                    F     PP P  +  L       G  G + K  
Sbjct: 931  GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282
             PG  G  G      GE G +G+ G PG  G    QGL
Sbjct: 974  PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 1010



 Score =  117 bits (293), Expect = 7e-26
 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%)

Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            PG PG QGP      PG PG NG  G +G    PGPRG  G  G +G  G  G  G PG 
Sbjct: 855  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 914

Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
            +G          PG  G QGP+G  G  G  G PGPPG  G  G  G RG +G +G  G 
Sbjct: 915  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 974

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228
             GP G+ GP+G  GE G           + +  H            PP P  EQ L    
Sbjct: 975  PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 1014

Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275
                   +PG + + G  G       PGE G  G         G G  G  G +GSPG++
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 1276 GAS 1278
            G++
Sbjct: 1075 GSA 1077



 Score =  117 bits (292), Expect = 9e-26
 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%)

Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114
            GPPGP GP G+   PG  G  G  G PG RGPPG  G  G  GLPG              
Sbjct: 454  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513

Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
                                     L+G PG  G+ GR G  G  G  G +G +G PGP 
Sbjct: 514  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            GPRG QG  G  G  G+RG PG  G  G+PG  G +G++G       L  L     H  +
Sbjct: 574  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 629

Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254
                     PP P            I  + L     P G  G R     PG+ G  G   
Sbjct: 630  ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 685

Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276
                  ++  +GEPG  GQ G+PG QG
Sbjct: 686  PPGPKGNMGPQGEPGPPGQQGNPGPQG 712



 Score =  116 bits (290), Expect = 2e-25
 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%)

Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125
            G PG QG PGL G  G    PG  G PG RG  G  G  G  G PG QG P   G +G P
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170
            G  G QGP G  G++G  GLPGP GP G                +G  G +G +G  GPP
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1164

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226
            G  GP G PG  G  GE G P+          Q     K D   E  R    PP PI  Q
Sbjct: 1165 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1212

Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275
             L   PG +       P+G PG       PG  G +G    +G +G PG+VG +G  G++
Sbjct: 1213 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266

Query: 1276 G 1276
            G
Sbjct: 1267 G 1267



 Score =  104 bits (259), Expect = 6e-22
 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103
            PGPPG +GPPG  G  G  GE+G                         PGP   RG PG 
Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427

Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163
             GE+G  G  G  G PG  G PG  GL+G  G +G +G  GL G  GP G QG  G RG 
Sbjct: 1428 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1487

Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191
             G +G PG  G  G+PGP G  G  G P
Sbjct: 1488 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%)

Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132
            PP  +  PG+P       E    G     G  GEKG  G P +         PG + ++G
Sbjct: 408  PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 454

Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192
            P            PGP GP G  G  G +G +G  G PG  GP G PG  G  G  G P 
Sbjct: 455  P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 502

Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240
            ++  L          SK  +          IL+Q     +  PG         P+G PG+
Sbjct: 503  TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 560

Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277
                   G+ G +G R ++G          RG PGA G  G PG+ GA
Sbjct: 561  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            PGP GP GPPG PG  G        GP+G  G  G  G  G  GL G PG  G PG V
Sbjct: 1503 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%)

Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928
           G    + + K AQL+     ++P    P + +I+F V+     P++    + ++  +   
Sbjct: 69  GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123

Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988
           +  + ++ G+  +  F  D         +       I  G +H+V ++V +  V + VDC
Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182

Query: 989 RKVAERPL 996
           +K   +PL
Sbjct: 183 KKKTTKPL 190


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  141 bits (356), Expect = 4e-33
 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120
            PGPPGP G  GLPG  G  G +G PGP+G      P G++G  G+ GLPG QG PG    
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173
               QG PG VG  G +G  G  G  GLPG PGP+G  G AG +G  GE+GP G       
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1067

Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             GP GLPGP G  G  GE      + +   + S   K ++      PP P       PG 
Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1115

Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
            + P+G+PG       PG  G+ G   + +G+ GA G  G PG  G   QGL
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1163



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127
            T G  GP GPPG  G  G  G  GFPGP+GPPG  G+ G  G PG +G  G QG  G   
Sbjct: 866  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925

Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183
                VG QGP G  G  G  G PGPPGP G QG+ GA G  G +G PG  G +G  GP G
Sbjct: 926  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985

Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243
             RG  GE        + +  A              PP P+            GSPG R  
Sbjct: 986  LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1025

Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            A   G  G  GR    +G PG  G+ G+PG++G
Sbjct: 1026 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1057



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGPQGPPG  G  G PGE+G  GP G  GV+G  G  G  G  G PG  G  G +G 
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1094

Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169
             G KG +G +G  G PGPPG                  PRG QGM G +G  G RG   P
Sbjct: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154

Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229
            PG +G  GLPGP GE+GE G+   +                        PP P   Q   
Sbjct: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1194

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                P G PG+       GE          +GEPG  G  G PG+ G
Sbjct: 1195 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1231



 Score =  133 bits (334), Expect = 1e-30
 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%)

Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
            GPPGP G      P G PG +G  GE G PGP+GP GV+G  G  G PG +G PG  G  
Sbjct: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549

Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173
            G  G  G KG RG +G  GLPG            PPGP G  GM G  G  G RG PG  
Sbjct: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            GP GL GP+G  G  G+P        +           +      P  P   Q+  PG  
Sbjct: 610  GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 658

Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            P G PG +     PGE G  G+     G PGA G  G PG++G S
Sbjct: 659  PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 702



 Score =  131 bits (329), Expect = 5e-30
 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%)

Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            PGP G   PQG PG PG+ G PG QG PGP+GP G  GEKG  G PGL G PG  G PG 
Sbjct: 636  PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
             G +G  G +G  G  G  GP   PGPRG +G  G RG  G +G  G  G  G  G  G 
Sbjct: 696  PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244
            +G++GE   +    +               +    P        +PG  P G  G + K 
Sbjct: 756  KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 798

Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             VPG  G  GR    +G  G+ G  G PG  G
Sbjct: 799  GVPGLPGYPGR----QGPKGSTGFPGFPGANG 826



 Score =  131 bits (329), Expect = 5e-30
 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPGP G  GLPG  G  GE G  GP GPPG  G +G  G  G  G    QG PG VG 
Sbjct: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1208

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G  G +G  G AG PGPPG  G  G  G RG  GE GPPG  GP G  GP G+ G KG 
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242
            P  +               F         P P  +  +        +PG    G PG   
Sbjct: 1269 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1312

Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            +A  PG  G+       RG PGA G  G  G++GA
Sbjct: 1313 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1340



 Score =  131 bits (329), Expect = 5e-30
 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPG +GPPG  G  G PG  GFPG  GPPG  G  G  G+ G +G  G  G PG  G  
Sbjct: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G  G  G  G  G PG  G  G QG  GA+G +G  GPPG  GP G  GP G+ G    P
Sbjct: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1367

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251
            + L  +                      P P+ EQ L       G PG      +PG  G
Sbjct: 1368 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1405

Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G   E +G PG +G +G PG+QG
Sbjct: 1406 DPGSKGE-KGHPGLIGLIGPPGEQG 1429



 Score =  130 bits (327), Expect = 8e-30
 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%)

Query: 997  GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056
            GE GS   AG + L      +GP   +             +  A  ++  + PA RDG  
Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1068

Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116
             P  +   +  + +PG  G +G  G PG+ G+ G++G  GP GPPG++G  G  G+ G  
Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1128

Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G PG +      G QG  G +G EG  G PGPPGP G QG+ G  G  GE G  G +GP 
Sbjct: 1129 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182

Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229
            G PGP+G +G  G   PQ                          PP  +     + +K E
Sbjct: 1183 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1217

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            PG    G+PG   +A V G  G  G   E  G PGA G  G+ G  G
Sbjct: 1218 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1261



 Score =  122 bits (305), Expect = 3e-27
 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P GE G P   G          RGP  ++ A   Q       +  A  +   E P  + G
Sbjct: 1310 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1354

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
               P   +         G PGP G  GLP   G  G+ G PGP GPPG+ G KGD G  G
Sbjct: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1411

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159
             +GHPG  G+ G  G QG KG RGL GT G P               GPPGP G  G  G
Sbjct: 1412 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1471

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             +G  G  GP G  G +GLPGP G  G  GE
Sbjct: 1472 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502



 Score =  120 bits (302), Expect = 6e-27
 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128
            G PGP G  G  G+ G PG  G+PG +GP   KG  G  G PG  G  G +G+   PG  
Sbjct: 784  GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 840

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G +GP G RG  G  G  G PGP+G  G  G  G  GERGP G  GP G PGPKG  G  
Sbjct: 841  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 900

Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243
            G+               H  +     F   T PP P   +  Q     T P+G  G    
Sbjct: 901  GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950

Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
               PGE G  G    EG +G+PG  G  G  G  G
Sbjct: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985



 Score =  120 bits (300), Expect = 1e-26
 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%)

Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115
            S     S  PGP GP   QGPPG    PG+ G PG  G  G  G PG KG++G  GLPGL
Sbjct: 510  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 569

Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151
             G  GH+G          PG  G++G               P+G+ G  GT G PG PG 
Sbjct: 570  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629

Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199
             G  G  G +G     GE GPP   G  GP GLPGP+      GE+G +G+P  LA L  
Sbjct: 630  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 688

Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256
                  H  K     E     PP P           P+G PG R      G  G +G + 
Sbjct: 689  ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 739

Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276
             +G  G PG  G MG  G +G
Sbjct: 740  EKGEDGFPGFKGDMGLKGDRG 760



 Score =  120 bits (300), Expect = 1e-26
 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G  GP G  G  G  G  G  G  GP G  GEKG  G+PGL G+PG QG  G  G  
Sbjct: 760  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185
            G  G  G +G  G+ G PGPRG +G  G RG+ G RGP G  GP G       PGP GER
Sbjct: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G PQ                    F     PP P  +  L       G  G + K  
Sbjct: 880  GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282
             PG  G  G      GE G +G+ G PG  G    QGL
Sbjct: 923  PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 959



 Score =  117 bits (293), Expect = 7e-26
 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%)

Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            PG PG QGP      PG PG NG  G +G    PGPRG  G  G +G  G  G  G PG 
Sbjct: 804  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863

Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
            +G          PG  G QGP+G  G  G  G PGPPG  G  G  G RG +G +G  G 
Sbjct: 864  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228
             GP G+ GP+G  GE G           + +  H            PP P  EQ L    
Sbjct: 924  PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 963

Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275
                   +PG + + G  G       PGE G  G         G G  G  G +GSPG++
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 1276 GAS 1278
            G++
Sbjct: 1024 GSA 1026



 Score =  117 bits (292), Expect = 9e-26
 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%)

Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114
            GPPGP GP G+   PG  G  G  G PG RGPPG  G  G  GLPG              
Sbjct: 403  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462

Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
                                     L+G PG  G+ GR G  G  G  G +G +G PGP 
Sbjct: 463  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            GPRG QG  G  G  G+RG PG  G  G+PG  G +G++G       L  L     H  +
Sbjct: 523  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 578

Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254
                     PP P            I  + L     P G  G R     PG+ G  G   
Sbjct: 579  ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 634

Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276
                  ++  +GEPG  GQ G+PG QG
Sbjct: 635  PPGPKGNMGPQGEPGPPGQQGNPGPQG 661



 Score =  116 bits (290), Expect = 2e-25
 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%)

Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125
            G PG QG PGL G  G    PG  G PG RG  G  G  G  G PG QG P   G +G P
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170
            G  G QGP G  G++G  GLPGP GP G                +G  G +G +G  GPP
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226
            G  GP G PG  G  GE G P+          Q     K D   E  R    PP PI  Q
Sbjct: 1114 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1161

Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275
             L   PG +       P+G PG       PG  G +G    +G +G PG+VG +G  G++
Sbjct: 1162 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215

Query: 1276 G 1276
            G
Sbjct: 1216 G 1216



 Score =  104 bits (259), Expect = 6e-22
 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103
            PGPPG +GPPG  G  G  GE+G                         PGP   RG PG 
Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376

Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163
             GE+G  G  G  G PG  G PG  GL+G  G +G +G  GL G  GP G QG  G RG 
Sbjct: 1377 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1436

Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191
             G +G PG  G  G+PGP G  G  G P
Sbjct: 1437 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%)

Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132
            PP  +  PG+P       E    G     G  GEKG  G P +         PG + ++G
Sbjct: 357  PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 403

Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192
            P            PGP GP G  G  G +G +G  G PG  GP G PG  G  G  G P 
Sbjct: 404  P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 451

Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240
            ++  L          SK  +          IL+Q     +  PG         P+G PG+
Sbjct: 452  TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 509

Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277
                   G+ G +G R ++G          RG PGA G  G PG+ GA
Sbjct: 510  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            PGP GP GPPG PG  G        GP+G  G  G  G  G  GL G PG  G PG V
Sbjct: 1452 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%)

Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928
           G    + + K AQL+     ++P    P + +I+F V+     P++    + ++  +   
Sbjct: 69  GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123

Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988
           +  + ++ G+  +  F  D         +       I  G +H+V ++V +  V + VDC
Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182

Query: 989 RKVAERPL 996
           +K   +PL
Sbjct: 183 KKKTTKPL 190


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  141 bits (356), Expect = 4e-33
 Identities = 94/231 (40%), Positives = 115/231 (49%), Gaps = 34/231 (14%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRG------PPGVKGEKGDHGLPGLQGHPG---- 1120
            PGPPGP G  GLPG  G  G +G PGP+G      P G++G  G+ GLPG QG PG    
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 1121 --HQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTV----- 1173
               QG PG VG  G +G  G  G  GLPG PGP+G  G AG +G  GE+GP G       
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1106

Query: 1174 -GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGT 1232
             GP GLPGP G  G  GE      + +   + S   K ++      PP P       PG 
Sbjct: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN-----GPPGP-------PGL 1154

Query: 1233 E-PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQGL 1282
            + P+G+PG       PG  G+ G   + +G+ GA G  G PG  G   QGL
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQ-KGDEGARGFPGPPGPIG--LQGL 1202



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/213 (40%), Positives = 100/213 (46%), Gaps = 27/213 (12%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR-- 1127
            T G  GP GPPG  G  G  G  GFPGP+GPPG  G+ G  G PG +G  G QG  G   
Sbjct: 905  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964

Query: 1128 ----VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKG 1183
                VG QGP G  G  G  G PGPPGP G QG+ GA G  G +G PG  G +G  GP G
Sbjct: 965  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024

Query: 1184 ERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSK 1243
             RG  GE        + +  A              PP P+            GSPG R  
Sbjct: 1025 LRGFPGE--------RGLPGAQGAPGLKGGEGPQGPPGPV------------GSPGERGS 1064

Query: 1244 ALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            A   G  G  GR    +G PG  G+ G+PG++G
Sbjct: 1065 AGTAGPIGLPGRP-GPQGPPGPAGEKGAPGEKG 1096



 Score =  133 bits (335), Expect = 1e-30
 Identities = 86/227 (37%), Positives = 99/227 (43%), Gaps = 51/227 (22%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGPQGPPG  G  G PGE+G  GP G  GV+G  G  G  G  G PG  G  G +G 
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGE 1133

Query: 1131 QGPKGMRGLEGTAGLPGPPG------------------PRGFQGMAGARGTSGERG---P 1169
             G KG +G +G  G PGPPG                  PRG QGM G +G  G RG   P
Sbjct: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193

Query: 1170 PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229
            PG +G  GLPGP GE+GE G+   +                        PP P   Q   
Sbjct: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGP--------------------PGPPGPRGPQGPN 1233

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                P G PG+       GE          +GEPG  G  G PG+ G
Sbjct: 1234 GADGPQGPPGSVGSVGGVGE----------KGEPGEAGNPGPPGEAG 1270



 Score =  133 bits (334), Expect = 1e-30
 Identities = 90/225 (40%), Positives = 104/225 (46%), Gaps = 30/225 (13%)

Query: 1072 GPPGPQG------PPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
            GPPGP G      P G PG +G  GE G PGP+GP GV+G  G  G PG +G PG  G  
Sbjct: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 1126 GRVGLQGPKGMRGLEGTAGLPG------------PPGPRGFQGMAGARGTSGERGPPGTV 1173
            G  G  G KG RG +G  GLPG            PPGP G  GM G  G  G RG PG  
Sbjct: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648

Query: 1174 GPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE 1233
            GP GL GP+G  G  G+P        +           +      P  P   Q+  PG  
Sbjct: 649  GPRGLLGPRGTPGAPGQP-------GMAGVDGPPGPKGNMGPQGEPGPP--GQQGNPG-- 697

Query: 1234 PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            P G PG +     PGE G  G+     G PGA G  G PG++G S
Sbjct: 698  PQGLPGPQGPIGPPGEKGPQGKP-GLAGLPGADGPPGHPGKEGQS 741



 Score =  131 bits (329), Expect = 5e-30
 Identities = 83/212 (39%), Positives = 99/212 (46%), Gaps = 27/212 (12%)

Query: 1071 PGPPG---PQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            PGP G   PQG PG PG+ G PG QG PGP+GP G  GEKG  G PGL G PG  G PG 
Sbjct: 675  PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 1128 VGLQGPKGMRGLEGTAGLPGP---PGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
             G +G  G +G  G  G  GP   PGPRG +G  G RG  G +G  G  G  G  G  G 
Sbjct: 735  PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKA 1244
            +G++GE   +    +               +    P        +PG  P G  G + K 
Sbjct: 795  KGDRGEVGQIGPRGE---------------DGPEGPKGRAGPTGDPG--PSGQAGEKGKL 837

Query: 1245 LVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             VPG  G  GR    +G  G+ G  G PG  G
Sbjct: 838  GVPGLPGYPGR----QGPKGSTGFPGFPGANG 865



 Score =  131 bits (329), Expect = 5e-30
 Identities = 86/215 (40%), Positives = 97/215 (45%), Gaps = 34/215 (15%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PGPPGP G  GLPG  G  GE G  GP GPPG  G +G  G  G  G    QG PG VG 
Sbjct: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP---QGPPGSVGS 1247

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G  G +G  G AG PGPPG  G  G  G RG  GE GPPG  GP G  GP G+ G KG 
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--------EPGTEPLGSPGTRS 1242
            P  +               F         P P  +  +        +PG    G PG   
Sbjct: 1308 PGPVG--------------FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP--GPPGPSG 1351

Query: 1243 KALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            +A  PG  G+       RG PGA G  G  G++GA
Sbjct: 1352 EAGPPGPPGK-------RGPPGAAGAEGRQGEKGA 1379



 Score =  131 bits (329), Expect = 5e-30
 Identities = 80/205 (39%), Positives = 94/205 (45%), Gaps = 27/205 (13%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPG +GPPG  G  G PG  GFPG  GPPG  G  G  G+ G +G  G  G PG  G  
Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1350

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G  G  G  G  G PG  G  G QG  GA+G +G  GPPG  GP G  GP G+ G    P
Sbjct: 1351 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG----P 1406

Query: 1192 QSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG 1251
            + L  +                      P P+ EQ L       G PG      +PG  G
Sbjct: 1407 EGLRGI----------------------PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1444

Query: 1252 RGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G   E +G PG +G +G PG+QG
Sbjct: 1445 DPGSKGE-KGHPGLIGLIGPPGEQG 1468



 Score =  130 bits (327), Expect = 8e-30
 Identities = 96/287 (33%), Positives = 127/287 (44%), Gaps = 53/287 (18%)

Query: 997  GEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGET 1056
            GE GS   AG + L      +GP   +             +  A  ++  + PA RDG  
Sbjct: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAG------------EKGAPGEKGPQGPAGRDGVQ 1107

Query: 1057 CPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQ 1116
             P  +   +  + +PG  G +G  G PG+ G+ G++G  GP GPPG++G  G  G+ G  
Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1167

Query: 1117 GHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
            G PG +      G QG  G +G EG  G PGPPGP G QG+ G  G  GE G  G +GP 
Sbjct: 1168 GEPGPR------GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221

Query: 1177 GLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPI-----LEQKLE 1229
            G PGP+G +G  G   PQ                          PP  +     + +K E
Sbjct: 1222 GPPGPRGPQGPNGADGPQG-------------------------PPGSVGSVGGVGEKGE 1256

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            PG    G+PG   +A V G  G  G   E  G PGA G  G+ G  G
Sbjct: 1257 PG--EAGNPGPPGEAGVGGPKGERGEKGEA-GPPGAAGPPGAKGPPG 1300



 Score =  122 bits (305), Expect = 3e-27
 Identities = 81/211 (38%), Positives = 93/211 (44%), Gaps = 33/211 (15%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P GE G P   G          RGP  ++ A   Q       +  A  +   E P  + G
Sbjct: 1349 PSGEAGPPGPPG---------KRGPPGAAGAEGRQ------GEKGAKGEAGAEGPPGKTG 1393

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG 1114
               P   +         G PGP G  GLP   G  G+ G PGP GPPG+ G KGD G  G
Sbjct: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLP---GAAGQDGPPGPMGPPGLPGLKGDPGSKG 1450

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---------------GPPGPRGFQGMAG 1159
             +GHPG  G+ G  G QG KG RGL GT G P               GPPGP G  G  G
Sbjct: 1451 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1510

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             +G  G  GP G  G +GLPGP G  G  GE
Sbjct: 1511 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541



 Score =  120 bits (302), Expect = 6e-27
 Identities = 83/215 (38%), Positives = 96/215 (44%), Gaps = 23/215 (10%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI---PGRV 1128
            G PGP G  G  G+ G PG  G+PG +GP   KG  G  G PG  G  G +G+   PG  
Sbjct: 823  GDPGPSGQAGEKGKLGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGVAGKPGPR 879

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G +GP G RG  G  G  G PGP+G  G  G  G  GERGP G  GP G PGPKG  G  
Sbjct: 880  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 939

Query: 1189 GEPQSLATLYQLVSQASHVSK--FDSFHENTRPPMP---ILEQKLEPGTEPLGSPGTRSK 1243
            G+               H  +     F   T PP P   +  Q     T P+G  G    
Sbjct: 940  GKD----------GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989

Query: 1244 ALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
               PGE G  G    EG +G+PG  G  G  G  G
Sbjct: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024



 Score =  120 bits (300), Expect = 1e-26
 Identities = 96/261 (36%), Positives = 114/261 (43%), Gaps = 56/261 (21%)

Query: 1062 SACSCSSETPGPPGP---QGPPG---LPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGL 1115
            S     S  PGP GP   QGPPG    PG+ G PG  G  G  G PG KG++G  GLPGL
Sbjct: 549  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 608

Query: 1116 QGHPGHQGI---------PGRVGLQG---------------PKGMRGLEGTAGLPGPPGP 1151
             G  GH+G          PG  G++G               P+G+ G  GT G PG PG 
Sbjct: 609  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668

Query: 1152 RGFQGMAGARGT---SGERGPP---GTVGPTGLPGPK------GERGEKGEPQSLATLYQ 1199
             G  G  G +G     GE GPP   G  GP GLPGP+      GE+G +G+P  LA L  
Sbjct: 669  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP-GLAGLPG 727

Query: 1200 LVSQASHVSKFDSFHEN--TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWG-RGGRH 1256
                  H  K     E     PP P           P+G PG R      G  G +G + 
Sbjct: 728  ADGPPGHPGKEGQSGEKGALGPPGP---------QGPIGYPGPRGVKGADGVRGLKGSKG 778

Query: 1257 LEGR-GEPGAVGQMGSPGQQG 1276
             +G  G PG  G MG  G +G
Sbjct: 779  EKGEDGFPGFKGDMGLKGDRG 799



 Score =  120 bits (300), Expect = 1e-26
 Identities = 84/218 (38%), Positives = 95/218 (43%), Gaps = 25/218 (11%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G  GP G  G  G  G  G  G  GP G  GEKG  G+PGL G+PG QG  G  G  
Sbjct: 799  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL------PGPKGER 1185
            G  G  G +G  G+ G PGPRG +G  G RG+ G RGP G  GP G       PGP GER
Sbjct: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G PQ                    F     PP P  +  L       G  G + K  
Sbjct: 919  GPQG-PQGPV----------------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG-ASTQGL 1282
             PG  G  G      GE G +G+ G PG  G    QGL
Sbjct: 962  PPGPGGVVGPQ-GPTGETGPIGERGHPGPPGPPGEQGL 998



 Score =  117 bits (293), Expect = 7e-26
 Identities = 86/243 (35%), Positives = 104/243 (42%), Gaps = 55/243 (22%)

Query: 1071 PGPPGPQGP------PGLPGRNGTPGEQGF---PGPRGPPGVKGEKGDHGLPGLQGHPGH 1121
            PG PG QGP      PG PG NG  G +G    PGPRG  G  G +G  G  G  G PG 
Sbjct: 843  PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902

Query: 1122 QGI---------PGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGT 1172
            +G          PG  G QGP+G  G  G  G PGPPG  G  G  G RG +G +G  G 
Sbjct: 903  KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962

Query: 1173 VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL---- 1228
             GP G+ GP+G  GE G           + +  H            PP P  EQ L    
Sbjct: 963  PGPGGVVGPQGPTGETGP----------IGERGHPG----------PPGPPGEQGLPGAA 1002

Query: 1229 -------EPGTEPL-GSPGTRSKALVPGEWGRGGRH-----LEGRGEPGAVGQMGSPGQQ 1275
                   +PG + + G  G       PGE G  G         G G  G  G +GSPG++
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 1276 GAS 1278
            G++
Sbjct: 1063 GSA 1065



 Score =  117 bits (292), Expect = 9e-26
 Identities = 89/267 (33%), Positives = 106/267 (39%), Gaps = 70/267 (26%)

Query: 1072 GPPGPQGPPGL---PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPG-------------- 1114
            GPPGP GP G+   PG  G  G  G PG RGPPG  G  G  GLPG              
Sbjct: 442  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501

Query: 1115 -------------------------LQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
                                     L+G PG  G+ GR G  G  G  G +G +G PGP 
Sbjct: 502  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            GPRG QG  G  G  G+RG PG  G  G+PG  G +G++G       L  L     H  +
Sbjct: 562  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG----FDGLPGLPGDKGHRGE 617

Query: 1210 FDSFHENTRPPMP------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGG--- 1254
                     PP P            I  + L     P G  G R     PG+ G  G   
Sbjct: 618  ----RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 673

Query: 1255 -----RHLEGRGEPGAVGQMGSPGQQG 1276
                  ++  +GEPG  GQ G+PG QG
Sbjct: 674  PPGPKGNMGPQGEPGPPGQQGNPGPQG 700



 Score =  116 bits (290), Expect = 2e-25
 Identities = 93/241 (38%), Positives = 109/241 (45%), Gaps = 54/241 (22%)

Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIP 1125
            G PG QG PGL G  G    PG  G PG RG  G  G  G  G PG QG P   G +G P
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGF---------------QGMAGARGTSGERGPP 1170
            G  G QGP G  G++G  GLPGP GP G                +G  G +G +G  GPP
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTR----PPMPILEQ 1226
            G  GP G PG  G  GE G P+          Q     K D   E  R    PP PI  Q
Sbjct: 1153 GLQGPVGAPGIAGGDGEPG-PRG--------QQGMFGQKGD---EGARGFPGPPGPIGLQ 1200

Query: 1227 KL--EPGTE-------PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQ 1275
             L   PG +       P+G PG       PG  G +G    +G +G PG+VG +G  G++
Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGP------PGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254

Query: 1276 G 1276
            G
Sbjct: 1255 G 1255



 Score =  104 bits (259), Expect = 6e-22
 Identities = 62/148 (41%), Positives = 70/148 (47%), Gaps = 27/148 (18%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGF------------------------PGP---RGPPGV 1103
            PGPPG +GPPG  G  G  GE+G                         PGP   RG PG 
Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415

Query: 1104 KGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGT 1163
             GE+G  G  G  G PG  G PG  GL+G  G +G +G  GL G  GP G QG  G RG 
Sbjct: 1416 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1475

Query: 1164 SGERGPPGTVGPTGLPGPKGERGEKGEP 1191
             G +G PG  G  G+PGP G  G  G P
Sbjct: 1476 PGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 68/228 (29%), Positives = 88/228 (38%), Gaps = 50/228 (21%)

Query: 1073 PPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQG 1132
            PP  +  PG+P       E    G     G  GEKG  G P +         PG + ++G
Sbjct: 396  PPNEEFGPGVPAETDIT-ETSINGH----GAYGEKGQKGEPAVVE-------PGML-VEG 442

Query: 1133 PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQ 1192
            P            PGP GP G  G  G +G +G  G PG  GP G PG  G  G  G P 
Sbjct: 443  P------------PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 490

Query: 1193 SLATLYQLVSQASHVSKFDSFHENTRPPMPILEQ-----KLEPG-------TEPLGSPGT 1240
            ++  L          SK  +          IL+Q     +  PG         P+G PG+
Sbjct: 491  TMLML--PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGS 548

Query: 1241 RSKALVPGEWG-RGGRHLEG----------RGEPGAVGQMGSPGQQGA 1277
                   G+ G +G R ++G          RG PGA G  G PG+ GA
Sbjct: 549  SGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 28/58 (48%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            PGP GP GPPG PG  G        GP+G  G  G  G  G  GL G PG  G PG V
Sbjct: 1491 PGPAGPLGPPGPPGLPGP------QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 7/128 (5%)

Query: 870 GGTPTFTLFKDAQLTRRVSDVYPA-PLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQP 928
           G    + + K AQL+     ++P    P + +I+F V+     P++    + ++  +   
Sbjct: 69  GSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVK-----PKKGIQSFLLSIYNEHG 123

Query: 929 LLGVLLDAGKKSLTYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDC 988
           +  + ++ G+  +  F  D         +       I  G +H+V ++V +  V + VDC
Sbjct: 124 IQQIGVEVGRSPVFLFE-DHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDC 182

Query: 989 RKVAERPL 996
           +K   +PL
Sbjct: 183 KKKTTKPL 190


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  141 bits (356), Expect = 4e-33
 Identities = 93/228 (40%), Positives = 112/228 (49%), Gaps = 21/228 (9%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PG  GP G  G  G PGE+G PG  G PG KG  G HG  G +G PG  G PG  G 
Sbjct: 698  PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G +GM G  G AG PGP G RG  G  GA GT+G  G  G  GP G PGP G  GEKGE
Sbjct: 758  PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817

Query: 1191 PQSLATLYQLVSQASHVSKFDSFHEN----TRPPMP-----ILEQKLEPGTE-PLGSPGT 1240
            P     +    S+ +  S+ ++          P  P     +  +  EPG +   GSPG 
Sbjct: 818  PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877

Query: 1241 RSKALVPGEWG-------RGGRHLEG----RGEPGAVGQMGSPGQQGA 1277
            +  A  PG  G       +GGR  +G     G PG+ G++G PG  GA
Sbjct: 878  QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGA 925



 Score =  135 bits (341), Expect = 2e-31
 Identities = 87/214 (40%), Positives = 106/214 (49%), Gaps = 18/214 (8%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            GPPG +G PG  G NG  G  GF GP+GP   PGVKGE G+ G  G  G PG QG+ G  
Sbjct: 825  GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP 884

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G  GP G+ GL+G  G  GPPG  GF G AG  G  G  G PG  GP G PG +G  G +
Sbjct: 885  GPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTE----PLGSPGTRSKA 1244
            G+P S    +  V             +   P      +  +PG +    P G+ G R   
Sbjct: 945  GDPGS----HGRVGDRGPAGPPGGPGDKGDP-----GEDGQPGPDGPPGPAGTTGQRGIV 995

Query: 1245 LVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
             +PG+ G RG   L G  G PG VG  G+ G +G
Sbjct: 996  GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKG 1029



 Score =  133 bits (335), Expect = 1e-30
 Identities = 89/216 (41%), Positives = 103/216 (47%), Gaps = 27/216 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP G PG  G  G  G++G PGP GPPG  G  G+   PG +G  G+ G PGR G 
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE---PGPEGPAGNDGTPGRDGA 1063

Query: 1131 QGPKGMRGLEGTAGLPGP------PGPRGFQGMAGARGTSGERGP---PGTVGPTGLPGP 1181
             G +G RG  G AGLPG       PGP G  G AG RG  G RGP   PG  G  GLPGP
Sbjct: 1064 VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGP 1123

Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241
            +G RG+KG+            Q  H   F        PP P  EQ         G PG  
Sbjct: 1124 QGPRGDKGDHGDRGDR----GQKGH-RGFTGLQGLPGPPGPNGEQ------GSAGIPGPF 1172

Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
                 PG  G  G+     G PG +G +G PG +G+
Sbjct: 1173 GPRGPPGPVGPSGK----EGNPGPLGPIGPPGVRGS 1204



 Score =  132 bits (332), Expect = 2e-30
 Identities = 83/208 (39%), Positives = 105/208 (50%), Gaps = 27/208 (12%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG +GPPGL G  G+ G  G  GP GPPG  G+KGD   PG  G PG  G PG  G  
Sbjct: 933  GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD---PGEDGQPGPDGPPGPAGTT 989

Query: 1132 GPKG---MRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G +G   M G  G  G+PG PGP G  G  G  G +G++GPPG VGP G  GP GE G +
Sbjct: 990  GQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE 1049

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            G   +  T  +  +      + D        P P       PG++  G+PGT      PG
Sbjct: 1050 GPAGNDGTPGRDGAVGERGDRGD--------PGP----AGLPGSQ--GAPGTPGPVGAPG 1095

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            + G+       RG+PG+ G +G PG+ G
Sbjct: 1096 DAGQ-------RGDPGSRGPIGPPGRAG 1116



 Score =  130 bits (328), Expect = 6e-30
 Identities = 87/220 (39%), Positives = 99/220 (45%), Gaps = 28/220 (12%)

Query: 1072 GPPGPQGPPGLPGRNG------TPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIP 1125
            GP GP+GP GL G+ G       PGE G PGP GP G +G +G  G PG  G PG  G P
Sbjct: 216  GPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP 275

Query: 1126 GRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGER 1185
            G VG  G  G RG  G  GLPG  G RG +G+ G +G  G  G  G  GPTG  G  G  
Sbjct: 276  GEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPL 335

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G P     L    +           H     P P+          PLG PG+     
Sbjct: 336  GPRGMPGERGRLGPQGAPGQR-----GAHGMPGKPGPM---------GPLGIPGSSGFPG 381

Query: 1246 VPGEWGR----GGRHLEG----RGEPGAVGQMGSPGQQGA 1277
             PG  G     G R  EG    RGE G  G +GSPG  GA
Sbjct: 382  NPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421



 Score =  130 bits (327), Expect = 8e-30
 Identities = 110/326 (33%), Positives = 129/326 (39%), Gaps = 92/326 (28%)

Query: 995  PLGEMGSPPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDG 1054
            P+G +G P ++GF     +    GP  +                     R  E P  + G
Sbjct: 367  PMGPLGIPGSSGFPGNPGMKGEAGPTGA---------------------RGPEGPQGQRG 405

Query: 1055 ETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGT------------PGEQGFPGPRGPPG 1102
            ET               GPPGP G PGLPG  GT            PG  G PG  GPPG
Sbjct: 406  ET---------------GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 1103 VKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP------GPRGFQG 1156
              G +G  G  G++G PG  G+PG  G  GPKG  G  G  G  GPP      GPRG  G
Sbjct: 451  SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510

Query: 1157 MAGARGTSGERGPPGT---VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
              G  G  GERG PG     G  GLPGPKG +GE+G   S                  S 
Sbjct: 511  TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK-------------GSQ 557

Query: 1214 HENTRPPMPILEQKL----EPGTE-------PLGSPGTRSKALVPGEWG----RGGRHLE 1258
             +  RP  P L         PG +       PLG+PG   +   PG  G     G   L 
Sbjct: 558  GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLP 617

Query: 1259 G-------RGEPGAVGQMGSPGQQGA 1277
            G        G+PG  G  G PGQ+GA
Sbjct: 618  GPKGSSGDPGKPGEAGNAGVPGQRGA 643



 Score =  129 bits (324), Expect = 2e-29
 Identities = 86/236 (36%), Positives = 104/236 (44%), Gaps = 22/236 (9%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P    G+  P  +     S    G  GP GPPG PG  G PGE G PGP GPPG  G  G
Sbjct: 931  PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168
              G+ G+ G  G +G+PG  G  G  G  G  G  G  GPPGP G  G  G  G  G  G
Sbjct: 991  QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG 1050

Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPI----- 1223
            P G  G  G  G  GERG++G+P                +           P P+     
Sbjct: 1051 PAGNDGTPGRDGAVGERGDRGDPGP--------------AGLPGSQGAPGTPGPVGAPGD 1096

Query: 1224 LEQKLEPGTE-PLGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
              Q+ +PG+  P+G PG   K  +PG  G RG +   G RG+ G  G  G  G QG
Sbjct: 1097 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152



 Score =  128 bits (322), Expect = 3e-29
 Identities = 82/213 (38%), Positives = 102/213 (47%), Gaps = 13/213 (6%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG  GPPG  G  G PG +GFPG  G PG KG +G+ G  G  G  G QG PGR G  
Sbjct: 507  GDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVG------PTGLPGPKGER 1185
            G  G RGL G    PG  GP G  G  GA G  G  GPPG++G        GLPGPKG  
Sbjct: 567  GLPGARGLTGN---PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G+ G+P           + +     +        P  +  ++ E G  P G  G +    
Sbjct: 624  GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG--PPGPTGFQGLPG 681

Query: 1246 VPGEWGRGGRHLEG--RGEPGAVGQMGSPGQQG 1276
             PG  G GG+  +    G+PGAVG +G  G++G
Sbjct: 682  PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERG 714



 Score =  127 bits (320), Expect = 5e-29
 Identities = 83/209 (39%), Positives = 98/209 (46%), Gaps = 18/209 (8%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            G  GP GP G+PG  G  G QG PG RG    PG  G  G  G+PG  G PG+ G+ G  
Sbjct: 330  GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389

Query: 1129 GLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            G  G +G  G +G  G  GPPGP G  G+ GA GT G    PG  GPTG PG  G  G  
Sbjct: 390  GPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT---PGAKGPTGSPGTSGPPGSA 446

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            G P S         Q       D       P +P  + +  P  EP G  G +     PG
Sbjct: 447  GPPGSPGPQGSTGPQGIRGQPGD-------PGVPGFKGEAGPKGEP-GPHGIQGPIGPPG 498

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            E G+ G     RG+PG VG  G  G++GA
Sbjct: 499  EEGKRG----PRGDPGTVGPPGPVGERGA 523



 Score =  127 bits (319), Expect = 7e-29
 Identities = 89/226 (39%), Positives = 109/226 (48%), Gaps = 27/226 (11%)

Query: 1071 PGPPGP---------QGPPGLPGRNGTPGEQGFPGP---RGPPGVKGEKGDHGLPGLQGH 1118
            PG PGP         +GPPG PG +G PG  G PG     G PG +G  G  GLPGL+GH
Sbjct: 242  PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301

Query: 1119 PGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGL 1178
             GH+      GL+GPKG  G  G+ G  GP GP G  G  G RG  GER   G +GP G 
Sbjct: 302  RGHK------GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGER---GRLGPQGA 352

Query: 1179 PGPKGERGEKGEPQSLATLYQLVSQ---ASHVSKFDSFHENTRPPMPILEQKLEPGTE-P 1234
            PG +G  G  G+P  +  L    S     +   K ++     R P     Q+ E G   P
Sbjct: 353  PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412

Query: 1235 LGSPGTRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278
            +GSPG        G  G +G     G  G PG+ G  GSPG QG++
Sbjct: 413  VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458



 Score =  127 bits (319), Expect = 7e-29
 Identities = 84/209 (40%), Positives = 103/209 (49%), Gaps = 11/209 (5%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG QGP G  G  G PGE G PGP G  G++G+ G  GLPG +G  G  G PG  G  
Sbjct: 576  GNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G  G RG  G  G  GP GP G  G+AG R   GE+GPPG  G  GLPGP G  GE G+P
Sbjct: 636  GVPGQRGAPGKDGEVGPSGPVGPPGLAGER---GEQGPPGPTGFQGLPGPPGPPGEGGKP 692

Query: 1192 --QSLATLYQLVSQASHVSKFDSFHENTRPPMPIL--EQKLEPGTEPLGSPGTRSKALVP 1247
              Q +      V       +  +  E   P +  L  E+ +  G  P G  G+   +  P
Sbjct: 693  GDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTP 752

Query: 1248 GEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            G+ G  G     +G PG  G  G+PG +G
Sbjct: 753  GDTGPPGL----QGMPGERGIAGTPGPKG 777



 Score =  126 bits (317), Expect = 1e-28
 Identities = 86/227 (37%), Positives = 103/227 (45%), Gaps = 31/227 (13%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPR---------GPPGVKGEKGDHGLPGLQGHPG 1120
            T GPPGP G  G PG  G PG  G PGP+         G  G KG +GD G PG  G PG
Sbjct: 511  TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570

Query: 1121 HQGIPGRVGLQGPKGM---RGLEGTAGLPGPPGPRGFQ------GMAGARGTSGERGPPG 1171
             +G+ G  G+QGP+G     G  G  G PGPPG  G +      G+ G +G+SG+ G PG
Sbjct: 571  ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG 630

Query: 1172 TVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLE 1229
              G  G+PG +G  G+ GE  P        L  +               PP P   Q L 
Sbjct: 631  EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG----------PPGPTGFQGLP 680

Query: 1230 PGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
                P G  G      VPG+ G  G  L  RGE G  G+ G PG  G
Sbjct: 681  GPPGPPGEGGKPGDQGVPGDPGAVG-PLGPRGERGNPGERGEPGITG 726



 Score =  125 bits (315), Expect = 2e-28
 Identities = 79/214 (36%), Positives = 96/214 (44%), Gaps = 33/214 (15%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            +PG  G  G PGLPG  G  G +G  GP+   G PG KGE G  G  G  G  G +G+PG
Sbjct: 283  SPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPG 342

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP+G  G  G  G+PG PGP G  G+ G+ G  G  G  G  GPTG  GP+G +G
Sbjct: 343  ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQG 402

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246
            ++GE                          T PP P+    L       G+PG +     
Sbjct: 403  QRGE--------------------------TGPPGPVGSPGLPGAIGTDGTPGAKGPTGS 436

Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280
            PG  G  G      G PG+ G  GS G QG   Q
Sbjct: 437  PGTSGPPG----SAGPPGSPGPQGSTGPQGIRGQ 466



 Score =  125 bits (315), Expect = 2e-28
 Identities = 82/236 (34%), Positives = 108/236 (45%), Gaps = 30/236 (12%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHP---GHQGIPGR 1127
            PG PGP GP G+PG +G PG  G  G  GP G +G +G  G  G  G P   G  G+PG 
Sbjct: 362  PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421

Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGE 1187
            +G  G  G +G  G+ G  GPPG  G  G  G +G++G +G  G  G  G+PG KGE G 
Sbjct: 422  IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481

Query: 1188 KGEPQSLATLYQLVSQASHVSKFDSFHENT-RPPMPILEQKLE-----PGTE-------- 1233
            KGEP        +        +       T  PP P+ E+        PG++        
Sbjct: 482  KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541

Query: 1234 -----PLGSPGTRSKALVPGEWGR----GGRHLEG----RGEPGAVGQMGSPGQQG 1276
                 P+GS G +     PG  G     G R L G    +G  G +G +G+PG+ G
Sbjct: 542  QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDG 597



 Score =  124 bits (310), Expect = 8e-28
 Identities = 90/236 (38%), Positives = 114/236 (48%), Gaps = 36/236 (15%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PGP GPPG  G  G  G +G PGPRGP G+ GE G  G PG  G PGH   PG  GL 
Sbjct: 129  GRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188

Query: 1132 GP--KGMRGLEGTAGL----------PGPPGPRGFQGMAGARGTSGERGPP--------- 1170
             P    M GL+  +GL           GP GPRG QG+ G +G +G  GPP         
Sbjct: 189  RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPM 248

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK-FDSFHENTRPPMPILE---- 1225
            G +G  G  GP G+ GE GEP       ++    S  ++ F        P +P L+    
Sbjct: 249  GPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG-----APGLPGLKGHRG 303

Query: 1226 -QKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEP---GAVGQMGSPGQQGA 1277
             + LE     +G+PG++ +A   G  G  G  L  RG P   G +G  G+PGQ+GA
Sbjct: 304  HKGLEGPKGEVGAPGSKGEAGPTGPMGAMG-PLGPRGMPGERGRLGPQGAPGQRGA 358



 Score =  123 bits (309), Expect = 1e-27
 Identities = 63/134 (47%), Positives = 75/134 (55%), Gaps = 9/134 (6%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRG---------PPGVKGEKGDHGLPGLQG 1117
            S   PG PGP G PG  G+ G PG +G  GP G         P G +G+KGDHG  G +G
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
              GH+G  G  GL GP G  G +G+AG+PGP GPRG  G  G  G  G  GP G +GP G
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG 1200

Query: 1178 LPGPKGERGEKGEP 1191
            + G  GE G +G P
Sbjct: 1201 VRGSVGEAGPEGPP 1214



 Score =  122 bits (307), Expect = 2e-27
 Identities = 90/236 (38%), Positives = 105/236 (44%), Gaps = 30/236 (12%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGP---PGLPGRNGTPGEQGFPGPRGPPGVKG 1105
            P    G+  P        S+   G PGP+GP    G PGR+G  GE+G  G  GP G+ G
Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080

Query: 1106 EKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSG 1165
             +G  G PG  G PG  G  G  G +GP G  G  G  GLPGP GPRG +G  G RG  G
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 1166 ERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILE 1225
            ++G  G  G  GLPGP G  GE+G              A     F        PP P+  
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQG-------------SAGIPGPFGP----RGPPGPVGP 1183

Query: 1226 QKLE--PG-TEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
               E  PG   P+G PG R      GE G  G      GEPG  G  G PG   A+
Sbjct: 1184 SGKEGNPGPLGPIGPPGVRGSV---GEAGPEG----PPGEPGPPGPPGPPGHLTAA 1232



 Score =  121 bits (304), Expect = 4e-27
 Identities = 90/249 (36%), Positives = 109/249 (43%), Gaps = 39/249 (15%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGP---PGVKGEKGDHGLPGLQGH----- 1118
            SS  PG PG  G  G+PG+ G PG+ G  GP GP   PG+ GE+G+ G PG  G      
Sbjct: 622  SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPG 681

Query: 1119 ----------PGHQGIPGRVGLQGPKGMRGLEGT---------AGLPGPPGPRGFQGMAG 1159
                      PG QG+PG  G  GP G RG  G           GLPG  G  G  G  G
Sbjct: 682  PPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG 741

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHEN--- 1216
             +G+ G  G PG  GP GL G  GERG  G P        +  + +  +  +        
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801

Query: 1217 -TRPPMPI--LEQKLEPGTEPL-GSPGTRSKALVPGEWG-RGGRHLEG----RGEPGAVG 1267
               PP P     +K EPG   L G PG+R      GE G  G     G     G+PG  G
Sbjct: 802  PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861

Query: 1268 QMGSPGQQG 1276
            + G PGQ+G
Sbjct: 862  EPGEPGQKG 870



 Score =  120 bits (302), Expect = 6e-27
 Identities = 87/246 (35%), Positives = 104/246 (42%), Gaps = 36/246 (14%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQ------GPPGLPGRNGTPGEQGFPGPRGPP- 1101
            P+   G+T P  +          G PGP+      G  G  G  G  G +G PGP GPP 
Sbjct: 748  PSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG 807

Query: 1102 --GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159
              G  GEKG+ G  GL G PG +G PG  G  GP G  G  G  G  G PG +G  G  G
Sbjct: 808  PAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG 867

Query: 1160 ARGTSGERGP------PGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
             +G +G  GP      PG  GP G+PG KG RG +G P +              + F   
Sbjct: 868  QKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGA--------------TGFPGS 913

Query: 1214 HENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWGRGGR--HLEGRGEPGAVGQMG 1270
                 PP P       PG   PLG PG      + G+ G  GR       G PG  G  G
Sbjct: 914  AGRVGPPGP----AGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG 969

Query: 1271 SPGQQG 1276
             PG+ G
Sbjct: 970  DPGEDG 975



 Score =  117 bits (294), Expect = 5e-26
 Identities = 94/261 (36%), Positives = 110/261 (42%), Gaps = 41/261 (15%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNG---TPGEQGF---PGPRGP-- 1100
            P SR GE  P      +      G PG +G PG PG+ G   +PG QG    PGP GP  
Sbjct: 833  PGSR-GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNG 891

Query: 1101 -PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAG 1159
             PG+KG +G  G PG  G PG     GRVG  GP G  G  G  G PG  GP G +G  G
Sbjct: 892  VPGLKGGRGTQGPPGATGFPGS---AGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPG 948

Query: 1160 ARGTSGERGPPGTVGPTGLPGPKGERGEKGE--PQSLATLYQLVSQASHVSKFDSFHENT 1217
            + G  G+RGP    GP G PG KG+ GE G+  P           Q   V       E  
Sbjct: 949  SHGRVGDRGP---AGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERG 1005

Query: 1218 RPPMP-------------ILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRH-------- 1256
             P +P                 K  PG  P+G PG+      PG  G  G          
Sbjct: 1006 MPGLPGPAGTPGKVGPTGATGDKGPPG--PVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063

Query: 1257 LEGRGEPGAVGQMGSPGQQGA 1277
            +  RG+ G  G  G PG QGA
Sbjct: 1064 VGERGDRGDPGPAGLPGSQGA 1084



 Score =  115 bits (289), Expect = 2e-25
 Identities = 85/226 (37%), Positives = 99/226 (43%), Gaps = 38/226 (16%)

Query: 1067 SSETPGPPGPQ---------GPPGLPGRNGTPGEQGFPGPR---GPPGVKGEKGDHGLPG 1114
            S   PGP G Q         GP G  G  G PGE G PG R   G PGV+G +G  G  G
Sbjct: 532  SDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLG 591

Query: 1115 LQGHPGHQGIPGRVGLQGPKGMRGL---EGTAGLPGPPGPRGFQGMAGARGTSGERGPPG 1171
              G  G  G PG +G++G  G  GL   +G++G PG PG  G  G+ G RG  G+ G  G
Sbjct: 592  APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG 651

Query: 1172 TVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG 1231
              GP G PG  GERGE+G P                     F     PP P  E   +PG
Sbjct: 652  PSGPVGPPGLAGERGEQGPPGP-----------------TGFQGLPGPPGPPGEGG-KPG 693

Query: 1232 TEPL-GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
             + + G PG        GE G  G     RGEPG  G  G  G  G
Sbjct: 694  DQGVPGDPGAVGPLGPRGERGNPGE----RGEPGITGLPGEKGMAG 735



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 85/262 (32%), Positives = 101/262 (38%), Gaps = 60/262 (22%)

Query: 1033 IVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQ 1092
            I+C      +   C  P +  GE CP         S+TPG           G N   G  
Sbjct: 69   ILCDKIECQDVLDCADPVTPPGECCPV-------CSQTPG-----------GGNTNFG-- 108

Query: 1093 GFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR 1152
                       +G KG  G PGL   P   GI GR G  GP G +G  G  G  G PGPR
Sbjct: 109  -----------RGRKGQKGEPGLV--PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPR 155

Query: 1153 GFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDS 1212
            G QG+ G  G  G+ G PG  G    PGP G       P S A +  L  ++   S+   
Sbjct: 156  GPQGIDGEPGVPGQPGAPGPPGHPSHPGPDG----LSRPFS-AQMAGLDEKSGLGSQVGL 210

Query: 1213 FHENTRPPMPILEQKL--------------EPGTE----PLGSPGTRSKALVPGEWGRGG 1254
               +  P  P   Q L              EPG      P+GS G       PGE G  G
Sbjct: 211  MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG 270

Query: 1255 RHLEGRGEPGAVGQMGSPGQQG 1276
            R+    G PG VG  GSPG +G
Sbjct: 271  RN----GNPGEVGFAGSPGARG 288



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 51/165 (30%), Positives = 65/165 (39%), Gaps = 44/165 (26%)

Query: 1116 QGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
            +G  G +G PG V +    G+RG  G AG PG  GPRG +G    +G  G RGP G  G 
Sbjct: 109  RGRKGQKGEPGLVPVV--TGIRGRPGPAGPPGSQGPRGERG---PKGRPGPRGPQGIDGE 163

Query: 1176 TGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPL 1235
             G+PG  G  G  G P             SH                       PG + L
Sbjct: 164  PGVPGQPGAPGPPGHP-------------SH-----------------------PGPDGL 187

Query: 1236 GSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQ 1280
              P +   A +  + G G    +    PG+VG +G  G QG   Q
Sbjct: 188  SRPFSAQMAGLDEKSGLGS---QVGLMPGSVGPVGPRGPQGLQGQ 229


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  141 bits (355), Expect = 5e-33
 Identities = 92/225 (40%), Positives = 107/225 (47%), Gaps = 43/225 (19%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKGDHGLPGLQG 1117
            S+  PGPPGP GP G  G  G  G+ G PG         P GPPG KGE GD G  G +G
Sbjct: 910  SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
             PG QG+ G+ G+ G  G RG  G  GLPGP G  G QG  GA   SG+RGPPG VGP G
Sbjct: 970  PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA---SGDRGPPGPVGPPG 1026

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP-----MPILEQKLEPGT 1232
            L GP GE G +G P +                         PP       +   + E G 
Sbjct: 1027 LTGPAGEPGREGSPGA-----------------------DGPPGRDGAAGVKGDRGETGA 1063

Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
              +G+PG       PG  G  G+  + RGE GA G MG  G  GA
Sbjct: 1064 --VGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGA 1105



 Score =  134 bits (338), Expect = 4e-31
 Identities = 95/262 (36%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGPQGP------PGLPGRNGTPGEQGFPGPRGPP 1101
            LP  R G T PA  +    +   PGP GP GP      PG PG  G  GE G  G RGP 
Sbjct: 328  LPGER-GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR--------- 1152
            G +G +G+ G PG  G  G  G PG  G+ G KG  G  G AG PG PGPR         
Sbjct: 387  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 1153 ---------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---RGEKGEPQSLATLYQL 1200
                     G  G+AG +G  G +G PG  GP G PGP GE   RG +GEP  +  +   
Sbjct: 447  GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWG-RGGRHLE 1258
              + +  ++     +    P     ++   G   P G+ G   +   PGE G  G R L 
Sbjct: 507  GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR---PGEPGLPGARGLT 563

Query: 1259 GR----GEPGAVGQMGSPGQQG 1276
            GR    G  G VG  G+PG+ G
Sbjct: 564  GRPGDAGPQGKVGPSGAPGEDG 585



 Score =  134 bits (338), Expect = 4e-31
 Identities = 99/255 (38%), Positives = 113/255 (44%), Gaps = 58/255 (22%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVKGEKG 1108
            +DGET  A            GPPGP GP G  G  G PG  GF   PGP GPPG  G+ G
Sbjct: 634  KDGETGAA------------GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681

Query: 1109 DHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGT---AGLPGPPGPRG 1153
            D G+PG             +G PG +G PG  GLQGP+G+ G  GT    G  GP GP G
Sbjct: 682  DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 741

Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
             QG  G +G  GERG  G  GP G  G  GE+G +G P                   D  
Sbjct: 742  AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-----------------DGG 784

Query: 1214 HENTRP-----PMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG--RGEPGA 1265
               T P     P     +K E G   P GS G R     PGE G  G        G PGA
Sbjct: 785  RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETGPPGPAGFAGPPGA 841

Query: 1266 VGQMGSPGQQGASTQ 1280
             GQ G+ G+QG + Q
Sbjct: 842  DGQPGAKGEQGEAGQ 856



 Score =  134 bits (336), Expect = 7e-31
 Identities = 91/246 (36%), Positives = 106/246 (43%), Gaps = 33/246 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            PA   GE         S     PGPPGP G  G PG  G PGE G PG  GP G +G  G
Sbjct: 646  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 705

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA-------- 1160
            + G PG QG  G +G+PG  G  GPKG  G  G  G  GPPG +G  G  GA        
Sbjct: 706  ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765

Query: 1161 -RGTSGERGPPGT---------VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210
             RG  GE+GP G           GP G PGP G  GEKGE           ++ +   + 
Sbjct: 766  DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825

Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270
            +     T PP P             G PG   +    GE G  G+  +  G PG  G  G
Sbjct: 826  E-----TGPPGP---------AGFAGPPGADGQPGAKGEQGEAGQKGDA-GAPGPQGPSG 870

Query: 1271 SPGQQG 1276
            +PG QG
Sbjct: 871  APGPQG 876



 Score =  134 bits (336), Expect = 7e-31
 Identities = 97/274 (35%), Positives = 114/274 (41%), Gaps = 52/274 (18%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            GE  P   +  + +   PG  G  GPPG  G  G PG  G PG +G  G  G+KGD G P
Sbjct: 804  GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 863

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGL------------------PGPPGPRGFQ 1155
            G QG  G  G  G  G+ GPKG RG +G  G                   PGPPGP G  
Sbjct: 864  GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923

Query: 1156 GMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP--------QSLATLYQLVSQASHV 1207
            G  G +G  G+ GPPG  G  GL GP G  GEKGEP        +       L  Q   V
Sbjct: 924  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 983

Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-------------PLGSPGTRSKALVPGEWGR-- 1252
                   E   P +P      EPG +             P+G PG    A  PG  G   
Sbjct: 984  GLPGQRGERGFPGLP--GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1041

Query: 1253 --------GGRHLEG-RGEPGAVGQMGSPGQQGA 1277
                    G   ++G RGE GAVG  G+PG  G+
Sbjct: 1042 ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075



 Score =  132 bits (331), Expect = 3e-30
 Identities = 94/248 (37%), Positives = 104/248 (41%), Gaps = 60/248 (24%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLP---------------GRNGTPGEQGFPGPR 1098
            GE     V   S S    G PGP GP GLP               G +G PG  G PGP 
Sbjct: 300  GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 359

Query: 1099 GP---------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
            GP         PG KGE G  G  G +G  G +G PG  G  GP G  G  GT G+PG  
Sbjct: 360  GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            G  G  G+AGA G  G RGPPG  G TG  GPKG+ GE G                    
Sbjct: 420  GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG-------------------- 459

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQM 1269
                         I   K E G  P G PG       PG  G  G+    RGEPG VG +
Sbjct: 460  -------------IAGFKGEQG--PKGEPGPAGPQGAPGPAGEEGKR-GARGEPGGVGPI 503

Query: 1270 GSPGQQGA 1277
            G PG++GA
Sbjct: 504  GPPGERGA 511



 Score =  130 bits (326), Expect = 1e-29
 Identities = 87/221 (39%), Positives = 98/221 (44%), Gaps = 37/221 (16%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPGP G PG  G  G PGE G PG  GP G +G  G  G PG  G  G  G  G  G  
Sbjct: 210  GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------------GTSGERGPPGTVGPTGLP 1179
            GP+G RG  GT GLPG  G RG+ G+ GA+            G+ GE G PG +GP GLP
Sbjct: 270  GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329

Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239
            G +G  G  G              A+     D       PP P+          P G PG
Sbjct: 330  GERGRTGPAG--------------AAGARGNDGQPGPAGPPGPV---------GPAGGPG 366

Query: 1240 TRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278
                    GE G  G R  EG +G  G  G  GSPG  GAS
Sbjct: 367  FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 407



 Score =  127 bits (320), Expect = 5e-29
 Identities = 83/212 (39%), Positives = 96/212 (45%), Gaps = 17/212 (8%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP G PG  G  G  G++G PGP GPPG+ G  G+   PG +G PG  G PGR G 
Sbjct: 995  PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGREGSPGADGPPGRDGA 1051

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G KG RG  G  G PG PGP G  G AG  G  G+RG  G  GP G  GP G RG +G 
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1111

Query: 1191 PQSLATLYQLVSQASHVSK----FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246
                    +         K    F        PP P  +Q     + P G  G R     
Sbjct: 1112 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ---GASGPAGPSGPRGP--- 1165

Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            PG  G  G+     G  G  G +G PG +G S
Sbjct: 1166 PGPVGPSGKD----GANGIPGPIGPPGPRGRS 1193



 Score =  127 bits (319), Expect = 7e-29
 Identities = 85/211 (40%), Positives = 101/211 (47%), Gaps = 27/211 (12%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G +GP G PG++G  G  G  GP GP G  GEKG+ G PG  G  G +G PG  G  
Sbjct: 768  GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185
            GP G  G  G  G  G PG +G QG AG +G +G  GP      PG  GPTG+ GPKG R
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G P +          A  V    S + N  PP P       PG  P G  G +    
Sbjct: 888  GAQGPPGATG----FPGAAGRVGPPGS-NGNPGPPGP-------PG--PSGKDGPKG--- 930

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G+ G  GR     GEPG  G  G PG++G
Sbjct: 931  ARGDSGPPGR----AGEPGLQGPAGPPGEKG 957



 Score =  125 bits (314), Expect = 3e-28
 Identities = 84/213 (39%), Positives = 95/213 (44%), Gaps = 20/213 (9%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPG 1126
            T GP G  GP G PG  G PG QG PG RG  G+   KG++GD G  G +G PG  G  G
Sbjct: 727  TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 786

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  G  G  GPPGP G  G  GA G  GE GPPG  G  G PG  G+ G
Sbjct: 787  LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKAL 1245
             KGE            Q     K D+     + P      +   G T P G+ G +    
Sbjct: 847  AKGE------------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 894

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
              G  G  GR     G PG+ G  G PG  G S
Sbjct: 895  ATGFPGAAGRV----GPPGSNGNPGPPGPPGPS 923



 Score =  125 bits (313), Expect = 3e-28
 Identities = 86/220 (39%), Positives = 97/220 (44%), Gaps = 24/220 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---GPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            PGP GPQG PG  G  G  G +G P   GP GPPG +G  G+ G PG  G  G +G PG 
Sbjct: 473  PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532

Query: 1128 ---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
                GL GPKG  G  G  G PG PG RG  G  G  G  G+ GP G  G  G PGP G 
Sbjct: 533  RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 592

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--EPGTEPL-GSPGTR 1241
            +G +G+P               V  F         P    E+ L   PG   L G  G  
Sbjct: 593  QGARGQP--------------GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 638

Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
              A  PG  G  G   E +G PG  G  G PG  G   +G
Sbjct: 639  GAAGPPGPAGPAGERGE-QGAPGPSGFQGLPGPPGPPGEG 677



 Score =  124 bits (310), Expect = 8e-28
 Identities = 85/219 (38%), Positives = 100/219 (45%), Gaps = 23/219 (10%)

Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            S  PG  G  GPPG  G  G PG  GFPGP+G  G  G+ G+ GLPG  G  G  G  G 
Sbjct: 578  SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637

Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE------RGPPGTVGPTGLPGP 1181
             G  GP G  G  G  G  G PGP GFQG+ G  G  GE      +G PG  G  GL GP
Sbjct: 638  TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 697

Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241
            +GERG  GE  S        +Q     +       T  P         PG +  G PG +
Sbjct: 698  RGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ--GPPGLQ 749

Query: 1242 SKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQG 1276
                +PGE  RG   + G    RG+ G  G  G+PG+ G
Sbjct: 750  G---MPGE--RGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783



 Score =  122 bits (306), Expect = 2e-27
 Identities = 80/233 (34%), Positives = 101/233 (43%), Gaps = 31/233 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P+ +DG   P      S      G PG QGP G PG  G PG+ G  G  GPPG +G  G
Sbjct: 922  PSGKDG---PKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168
              G+ GL G  G +G PG  G  G  G +G  G +G  GPPGP G  G+ G  G  G  G
Sbjct: 979  QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 1038

Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228
             PG  GP G  G  G +G++GE  ++                        P  P      
Sbjct: 1039 SPGADGPPGRDGAAGVKGDRGETGAVGA----------------------PGAPGPPGSP 1076

Query: 1229 EPGTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
             P   P G  G R +A   G  G     G R ++G +G  G  G+ G PG++G
Sbjct: 1077 GP-AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1128



 Score =  120 bits (302), Expect = 6e-27
 Identities = 82/214 (38%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG  G  GLPG++G  G  G PGP GP G +GE+G  G  G QG PG  G PG  G  
Sbjct: 621  GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 680

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185
            G +G+ G  G  GL GP G RGF G  G+ G  G +GP      PGT GP G  GP G  
Sbjct: 681  GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 740

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244
            G +G P       +  +      K D      + P     +    G T P+G PG     
Sbjct: 741  GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 800

Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
               GE G  G       RG PG  G+ G PG  G
Sbjct: 801  GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834



 Score =  120 bits (300), Expect = 1e-26
 Identities = 101/317 (31%), Positives = 123/317 (38%), Gaps = 80/317 (25%)

Query: 1033 IVCSDTWADEDRCCELPASRDGETCPAFVSACSCSSETPGP------------------- 1073
            ++C D   ++ + C  P    GE CP   +  + +S  PGP                   
Sbjct: 62   VLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGP 121

Query: 1074 PGPQGP------------------PGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHG---- 1111
            PGPQGP                  PG  GR+G PG  G PGP GPPG  G  G  G    
Sbjct: 122  PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181

Query: 1112 -----------------LPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLP---GPPGP 1151
                             + G  G  G +G PG  G  GP+G +G  G  G P   GP GP
Sbjct: 182  QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 241

Query: 1152 RGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFD 1211
            RG  G  G  G  GE G PG  G  G PGP+G RG  G P     L  +     +     
Sbjct: 242  RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP----GLPGVKGHRGYPGLDG 297

Query: 1212 SFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGR-------GGRHLEGR---- 1260
            +  E   P   +  +   PG    GSPG      +PGE GR       G R  +G+    
Sbjct: 298  AKGEAGAP--GVKGESGSPGEN--GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353

Query: 1261 GEPGAVGQMGSPGQQGA 1277
            G PG VG  G PG  GA
Sbjct: 354  GPPGPVGPAGGPGFPGA 370



 Score =  117 bits (292), Expect = 9e-26
 Identities = 83/208 (39%), Positives = 92/208 (44%), Gaps = 42/208 (20%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG  G PGLPG  G  G  G  GP+G  G  G  G+ G PG  G  G +G PG +G  
Sbjct: 546  GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 605

Query: 1132 GPKGMRGLEGTAG---LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            GPKG  G  G AG   LPG P         G RG  G+ G  G  GP G  GP GERGE+
Sbjct: 606  GPKGANGEPGKAGEKGLPGAP---------GLRGLPGKDGETGAAGPPGPAGPAGERGEQ 656

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            G P                     F     PP P       PG    G PG +    VPG
Sbjct: 657  GAPGP-----------------SGFQGLPGPPGP-------PGEG--GKPGDQG---VPG 687

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            E G  G  +  RGE G  G+ GSPG QG
Sbjct: 688  EAGAPGL-VGPRGERGFPGERGSPGAQG 714



 Score =  101 bits (251), Expect = 5e-21
 Identities = 56/120 (46%), Positives = 62/120 (51%), Gaps = 6/120 (5%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP GP GP       G  G QG  GPRG  G  GE G+ GL G +G  G QG+PG  G  
Sbjct: 1095 GPMGPSGPA------GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G +G  G  G +G  GPPGP G  G  GA G  G  GPPG  G +G  GP G  G  G P
Sbjct: 1149 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 45/116 (38%), Positives = 49/116 (42%), Gaps = 24/116 (20%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP G +G  G PG  G  G +GF G +G PG  G  GD G  G  G  G +G PG VG  
Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1172

Query: 1132 G------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
            G            P G RG  G  G  GPP            G  G  GPPG  GP
Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPP------------GNPGPPGPPGPPGP 1216



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 44/111 (39%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            +S   GP GP+GPPG  G +G  G  G PGP GPPG +G  G+ G  G  G+PG  G PG
Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212

Query: 1127 RVGLQGPKGMRGLEGTAGL-PGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
              G     G+  +   AGL P   GP   Q M   +   G R     V  T
Sbjct: 1213 PPG----PGI-DMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDAT 1258



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 24/57 (42%), Positives = 27/57 (47%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG 1105
            P+   G   P   S    ++  PGP GP GP G  G  G  G  G PGP GPPG  G
Sbjct: 1159 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/60 (43%), Positives = 27/60 (45%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            PA   G   P      S      G PGP GPPG  GR+G  G  G PG  GPPG  G  G
Sbjct: 1156 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1215


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  141 bits (355), Expect = 5e-33
 Identities = 92/225 (40%), Positives = 107/225 (47%), Gaps = 43/225 (19%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPG---------PRGPPGVKGEKGDHGLPGLQG 1117
            S+  PGPPGP GP G  G  G  G+ G PG         P GPPG KGE GD G  G +G
Sbjct: 841  SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900

Query: 1118 HPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTG 1177
             PG QG+ G+ G+ G  G RG  G  GLPGP G  G QG  GA   SG+RGPPG VGP G
Sbjct: 901  PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA---SGDRGPPGPVGPPG 957

Query: 1178 LPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPP-----MPILEQKLEPGT 1232
            L GP GE G +G P +                         PP       +   + E G 
Sbjct: 958  LTGPAGEPGREGSPGA-----------------------DGPPGRDGAAGVKGDRGETGA 994

Query: 1233 EPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
              +G+PG       PG  G  G+  + RGE GA G MG  G  GA
Sbjct: 995  --VGAPGAPGPPGSPGPAGPTGKQGD-RGEAGAQGPMGPSGPAGA 1036



 Score =  134 bits (338), Expect = 4e-31
 Identities = 95/262 (36%), Positives = 118/262 (45%), Gaps = 37/262 (14%)

Query: 1048 LPASRDGETCPAFVSACSCSSETPGPPGPQGP------PGLPGRNGTPGEQGFPGPRGPP 1101
            LP  R G T PA  +    +   PGP GP GP      PG PG  G  GE G  G RGP 
Sbjct: 259  LPGER-GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317

Query: 1102 GVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPR--------- 1152
            G +G +G+ G PG  G  G  G PG  G+ G KG  G  G AG PG PGPR         
Sbjct: 318  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377

Query: 1153 ---------GFQGMAGARGTSGERGPPGTVGPTGLPGPKGE---RGEKGEPQSLATLYQL 1200
                     G  G+AG +G  G +G PG  GP G PGP GE   RG +GEP  +  +   
Sbjct: 378  GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437

Query: 1201 VSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKALVPGEWG-RGGRHLE 1258
              + +  ++     +    P     ++   G   P G+ G   +   PGE G  G R L 
Sbjct: 438  GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR---PGEPGLPGARGLT 494

Query: 1259 GR----GEPGAVGQMGSPGQQG 1276
            GR    G  G VG  G+PG+ G
Sbjct: 495  GRPGDAGPQGKVGPSGAPGEDG 516



 Score =  134 bits (338), Expect = 4e-31
 Identities = 99/255 (38%), Positives = 113/255 (44%), Gaps = 58/255 (22%)

Query: 1052 RDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGF---PGPRGPPGVKGEKG 1108
            +DGET  A            GPPGP GP G  G  G PG  GF   PGP GPPG  G+ G
Sbjct: 565  KDGETGAA------------GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612

Query: 1109 DHGLPGL------------QGHPGHQGIPGRVGLQGPKGMRGLEGT---AGLPGPPGPRG 1153
            D G+PG             +G PG +G PG  GLQGP+G+ G  GT    G  GP GP G
Sbjct: 613  DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 672

Query: 1154 FQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSF 1213
             QG  G +G  GERG  G  GP G  G  GE+G +G P                   D  
Sbjct: 673  AQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK-----------------DGG 715

Query: 1214 HENTRP-----PMPILEQKLEPGTE-PLGSPGTRSKALVPGEWGRGGRHLEG--RGEPGA 1265
               T P     P     +K E G   P GS G R     PGE G  G        G PGA
Sbjct: 716  RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETGPPGPAGFAGPPGA 772

Query: 1266 VGQMGSPGQQGASTQ 1280
             GQ G+ G+QG + Q
Sbjct: 773  DGQPGAKGEQGEAGQ 787



 Score =  134 bits (336), Expect = 7e-31
 Identities = 91/246 (36%), Positives = 106/246 (43%), Gaps = 33/246 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            PA   GE         S     PGPPGP G  G PG  G PGE G PG  GP G +G  G
Sbjct: 577  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGA-------- 1160
            + G PG QG  G +G+PG  G  GPKG  G  G  G  GPPG +G  G  GA        
Sbjct: 637  ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696

Query: 1161 -RGTSGERGPPGT---------VGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210
             RG  GE+GP G           GP G PGP G  GEKGE           ++ +   + 
Sbjct: 697  DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756

Query: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270
            +     T PP P             G PG   +    GE G  G+  +  G PG  G  G
Sbjct: 757  E-----TGPPGP---------AGFAGPPGADGQPGAKGEQGEAGQKGDA-GAPGPQGPSG 801

Query: 1271 SPGQQG 1276
            +PG QG
Sbjct: 802  APGPQG 807



 Score =  134 bits (336), Expect = 7e-31
 Identities = 97/274 (35%), Positives = 114/274 (41%), Gaps = 52/274 (18%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP 1113
            GE  P   +  + +   PG  G  GPPG  G  G PG  G PG +G  G  G+KGD G P
Sbjct: 735  GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAP 794

Query: 1114 GLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGL------------------PGPPGPRGFQ 1155
            G QG  G  G  G  G+ GPKG RG +G  G                   PGPPGP G  
Sbjct: 795  GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854

Query: 1156 GMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP--------QSLATLYQLVSQASHV 1207
            G  G +G  G+ GPPG  G  GL GP G  GEKGEP        +       L  Q   V
Sbjct: 855  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914

Query: 1208 SKFDSFHENTRPPMPILEQKLEPGTE-------------PLGSPGTRSKALVPGEWGR-- 1252
                   E   P +P      EPG +             P+G PG    A  PG  G   
Sbjct: 915  GLPGQRGERGFPGLP--GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972

Query: 1253 --------GGRHLEG-RGEPGAVGQMGSPGQQGA 1277
                    G   ++G RGE GAVG  G+PG  G+
Sbjct: 973  ADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006



 Score =  132 bits (331), Expect = 3e-30
 Identities = 94/248 (37%), Positives = 104/248 (41%), Gaps = 60/248 (24%)

Query: 1054 GETCPAFVSACSCSSETPGPPGPQGPPGLP---------------GRNGTPGEQGFPGPR 1098
            GE     V   S S    G PGP GP GLP               G +G PG  G PGP 
Sbjct: 231  GEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPV 290

Query: 1099 GP---------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149
            GP         PG KGE G  G  G +G  G +G PG  G  GP G  G  GT G+PG  
Sbjct: 291  GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350

Query: 1150 GPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSK 1209
            G  G  G+AGA G  G RGPPG  G TG  GPKG+ GE G                    
Sbjct: 351  GSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG-------------------- 390

Query: 1210 FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQM 1269
                         I   K E G  P G PG       PG  G  G+    RGEPG VG +
Sbjct: 391  -------------IAGFKGEQG--PKGEPGPAGPQGAPGPAGEEGKR-GARGEPGGVGPI 434

Query: 1270 GSPGQQGA 1277
            G PG++GA
Sbjct: 435  GPPGERGA 442



 Score =  130 bits (326), Expect = 1e-29
 Identities = 87/221 (39%), Positives = 98/221 (44%), Gaps = 37/221 (16%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GPPGP G PG  G  G PGE G PG  GP G +G  G  G PG  G  G  G  G  G  
Sbjct: 141  GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGAR------------GTSGERGPPGTVGPTGLP 1179
            GP+G RG  GT GLPG  G RG+ G+ GA+            G+ GE G PG +GP GLP
Sbjct: 201  GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260

Query: 1180 GPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPG 1239
            G +G  G  G              A+     D       PP P+          P G PG
Sbjct: 261  GERGRTGPAG--------------AAGARGNDGQPGPAGPPGPV---------GPAGGPG 297

Query: 1240 TRSKALVPGEWG-RGGRHLEG-RGEPGAVGQMGSPGQQGAS 1278
                    GE G  G R  EG +G  G  G  GSPG  GAS
Sbjct: 298  FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338



 Score =  127 bits (320), Expect = 5e-29
 Identities = 83/212 (39%), Positives = 96/212 (45%), Gaps = 17/212 (8%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130
            PG PGP G PG  G  G  G++G PGP GPPG+ G  G+   PG +G PG  G PGR G 
Sbjct: 926  PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE---PGREGSPGADGPPGRDGA 982

Query: 1131 QGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGE 1190
             G KG RG  G  G PG PGP G  G AG  G  G+RG  G  GP G  GP G RG +G 
Sbjct: 983  AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1042

Query: 1191 PQSLATLYQLVSQASHVSK----FDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALV 1246
                    +         K    F        PP P  +Q     + P G  G R     
Sbjct: 1043 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ---GASGPAGPSGPRGP--- 1096

Query: 1247 PGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
            PG  G  G+     G  G  G +G PG +G S
Sbjct: 1097 PGPVGPSGKD----GANGIPGPIGPPGPRGRS 1124



 Score =  127 bits (319), Expect = 7e-29
 Identities = 85/211 (40%), Positives = 101/211 (47%), Gaps = 27/211 (12%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G  G +GP G PG++G  G  G  GP GP G  GEKG+ G PG  G  G +G PG  G  
Sbjct: 699  GDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185
            GP G  G  G  G  G PG +G QG AG +G +G  GP      PG  GPTG+ GPKG R
Sbjct: 759  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKAL 1245
            G +G P +          A  V    S + N  PP P       PG  P G  G +    
Sbjct: 819  GAQGPPGATG----FPGAAGRVGPPGS-NGNPGPPGP-------PG--PSGKDGPKG--- 861

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
              G+ G  GR     GEPG  G  G PG++G
Sbjct: 862  ARGDSGPPGR----AGEPGLQGPAGPPGEKG 888



 Score =  125 bits (314), Expect = 3e-28
 Identities = 84/213 (39%), Positives = 95/213 (44%), Gaps = 20/213 (9%)

Query: 1070 TPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGV---KGEKGDHGLPGLQGHPGHQGIPG 1126
            T GP G  GP G PG  G PG QG PG RG  G+   KG++GD G  G +G PG  G  G
Sbjct: 658  TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRG 717

Query: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186
              G  GP G  G  G  G  GPPGP G  G  GA G  GE GPPG  G  G PG  G+ G
Sbjct: 718  LTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 777

Query: 1187 EKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKAL 1245
             KGE            Q     K D+     + P      +   G T P G+ G +    
Sbjct: 778  AKGE------------QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 825

Query: 1246 VPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGAS 1278
              G  G  GR     G PG+ G  G PG  G S
Sbjct: 826  ATGFPGAAGRV----GPPGSNGNPGPPGPPGPS 854



 Score =  125 bits (313), Expect = 3e-28
 Identities = 86/220 (39%), Positives = 97/220 (44%), Gaps = 24/220 (10%)

Query: 1071 PGPPGPQGPPGLPGRNGTPGEQGFP---GPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            PGP GPQG PG  G  G  G +G P   GP GPPG +G  G+ G PG  G  G +G PG 
Sbjct: 404  PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 463

Query: 1128 ---VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGE 1184
                GL GPKG  G  G  G PG PG RG  G  G  G  G+ GP G  G  G PGP G 
Sbjct: 464  RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 523

Query: 1185 RGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL--EPGTEPL-GSPGTR 1241
            +G +G+P               V  F         P    E+ L   PG   L G  G  
Sbjct: 524  QGARGQP--------------GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569

Query: 1242 SKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGASTQG 1281
              A  PG  G  G   E +G PG  G  G PG  G   +G
Sbjct: 570  GAAGPPGPAGPAGERGE-QGAPGPSGFQGLPGPPGPPGEG 608



 Score =  124 bits (310), Expect = 8e-28
 Identities = 85/219 (38%), Positives = 100/219 (45%), Gaps = 23/219 (10%)

Query: 1068 SETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGR 1127
            S  PG  G  GPPG  G  G PG  GFPGP+G  G  G+ G+ GLPG  G  G  G  G 
Sbjct: 509  SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568

Query: 1128 VGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGE------RGPPGTVGPTGLPGP 1181
             G  GP G  G  G  G  G PGP GFQG+ G  G  GE      +G PG  G  GL GP
Sbjct: 569  TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 628

Query: 1182 KGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTR 1241
            +GERG  GE  S        +Q     +       T  P         PG +  G PG +
Sbjct: 629  RGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ--GPPGLQ 680

Query: 1242 SKALVPGEWGRGGRHLEG----RGEPGAVGQMGSPGQQG 1276
                +PGE  RG   + G    RG+ G  G  G+PG+ G
Sbjct: 681  G---MPGE--RGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714



 Score =  122 bits (306), Expect = 2e-27
 Identities = 80/233 (34%), Positives = 101/233 (43%), Gaps = 31/233 (13%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            P+ +DG   P      S      G PG QGP G PG  G PG+ G  G  GPPG +G  G
Sbjct: 853  PSGKDG---PKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909

Query: 1109 DHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERG 1168
              G+ GL G  G +G PG  G  G  G +G  G +G  GPPGP G  G+ G  G  G  G
Sbjct: 910  QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969

Query: 1169 PPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKL 1228
             PG  GP G  G  G +G++GE  ++                        P  P      
Sbjct: 970  SPGADGPPGRDGAAGVKGDRGETGAVGA----------------------PGAPGPPGSP 1007

Query: 1229 EPGTEPLGSPGTRSKALVPGEWG----RGGRHLEG-RGEPGAVGQMGSPGQQG 1276
             P   P G  G R +A   G  G     G R ++G +G  G  G+ G PG++G
Sbjct: 1008 GP-AGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERG 1059



 Score =  120 bits (302), Expect = 6e-27
 Identities = 82/214 (38%), Positives = 97/214 (45%), Gaps = 9/214 (4%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG  G  GLPG++G  G  G PGP GP G +GE+G  G  G QG PG  G PG  G  
Sbjct: 552  GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP 611

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGP------PGTVGPTGLPGPKGER 1185
            G +G+ G  G  GL GP G RGF G  G+ G  G +GP      PGT GP G  GP G  
Sbjct: 612  GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP 671

Query: 1186 GEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPG-TEPLGSPGTRSKA 1244
            G +G P       +  +      K D      + P     +    G T P+G PG     
Sbjct: 672  GAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN 731

Query: 1245 LVPGEWGRGG--RHLEGRGEPGAVGQMGSPGQQG 1276
               GE G  G       RG PG  G+ G PG  G
Sbjct: 732  GEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765



 Score =  118 bits (296), Expect = 3e-26
 Identities = 83/227 (36%), Positives = 95/227 (41%), Gaps = 48/227 (21%)

Query: 1072 GPPGPQGPPGLPGRNGT---PGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRV 1128
            GPPGPQGP G  G  G     GE+G PGPRG  G  G  G+ G PG  G PG  G+ G  
Sbjct: 51   GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110

Query: 1129 G------------------LQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPP 1170
                               +QGP G  G  G  G  G PGP+GFQG  G  G  G  GP 
Sbjct: 111  AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 170

Query: 1171 GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEP 1230
            G  GP G PG  G+ GE G+P                           PP P   +   P
Sbjct: 171  GPRGPPGPPGKPGDDGEAGKPGKAG--------------------ERGPPGPQGARGF-P 209

Query: 1231 GTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPGQQGA 1277
            GT   G PG +     PG  G  G      G PG  G+ GSPG+ G+
Sbjct: 210  GTP--GLPGVKGHRGYPGLDGAKGE----AGAPGVKGESGSPGENGS 250



 Score =  117 bits (292), Expect = 9e-26
 Identities = 83/208 (39%), Positives = 92/208 (44%), Gaps = 42/208 (20%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            G PG  G PGLPG  G  G  G  GP+G  G  G  G+ G PG  G  G +G PG +G  
Sbjct: 477  GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536

Query: 1132 GPKGMRGLEGTAG---LPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEK 1188
            GPKG  G  G AG   LPG P         G RG  G+ G  G  GP G  GP GERGE+
Sbjct: 537  GPKGANGEPGKAGEKGLPGAP---------GLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587

Query: 1189 GEPQSLATLYQLVSQASHVSKFDSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPG 1248
            G P                     F     PP P       PG    G PG +    VPG
Sbjct: 588  GAPGP-----------------SGFQGLPGPPGP-------PGEG--GKPGDQG---VPG 618

Query: 1249 EWGRGGRHLEGRGEPGAVGQMGSPGQQG 1276
            E G  G  +  RGE G  G+ GSPG QG
Sbjct: 619  EAGAPGL-VGPRGERGFPGERGSPGAQG 645



 Score =  101 bits (251), Expect = 5e-21
 Identities = 56/120 (46%), Positives = 62/120 (51%), Gaps = 6/120 (5%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP GP GP       G  G QG  GPRG  G  GE G+ GL G +G  G QG+PG  G  
Sbjct: 1026 GPMGPSGPA------GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079

Query: 1132 GPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEP 1191
            G +G  G  G +G  GPPGP G  G  GA G  G  GPPG  G +G  GP G  G  G P
Sbjct: 1080 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139



 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 75/243 (30%), Positives = 89/243 (36%), Gaps = 84/243 (34%)

Query: 1066 CSSETPGPPGPQGPPGLPGR-NGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGI 1124
            C  +    PGP+G  G PG      G +G PGP+GP G +G +GD G  G +G PG    
Sbjct: 23   CQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP--- 79

Query: 1125 PGRVGLQGPKGMRGLEGTAGLP------GPPGPRGFQGMAG------------------- 1159
                        RG +G  G P      GPPGP G  G+ G                   
Sbjct: 80   ------------RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127

Query: 1160 --ARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKFDSFHENT 1217
               +G  G  GP G  GP G PGP+G +G  GEP                          
Sbjct: 128  GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG------------------------- 162

Query: 1218 RPPMPILEQKLEPGTE----PLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMGSPG 1273
                       EPG      P G PG   K    GE G+ G+  E RG PG  G  G PG
Sbjct: 163  -----------EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE-RGPPGPQGARGFPG 210

Query: 1274 QQG 1276
              G
Sbjct: 211  TPG 213



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 45/116 (38%), Positives = 49/116 (42%), Gaps = 24/116 (20%)

Query: 1072 GPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQ 1131
            GP G +G  G PG  G  G +GF G +G PG  G  GD G  G  G  G +G PG VG  
Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1103

Query: 1132 G------------PKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGP 1175
            G            P G RG  G  G  GPP            G  G  GPPG  GP
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPP------------GNPGPPGPPGPPGP 1147



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 44/111 (39%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126
            +S   GP GP+GPPG  G +G  G  G PGP GPPG +G  G+ G  G  G+PG  G PG
Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143

Query: 1127 RVGLQGPKGMRGLEGTAGL-PGPPGPRGFQGMAGARGTSGERGPPGTVGPT 1176
              G     G+  +   AGL P   GP   Q M   +   G R     V  T
Sbjct: 1144 PPG----PGI-DMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDAEVDAT 1189



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 24/57 (42%), Positives = 27/57 (47%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKG 1105
            P+   G   P   S    ++  PGP GP GP G  G  G  G  G PGP GPPG  G
Sbjct: 1090 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/60 (43%), Positives = 27/60 (45%)

Query: 1049 PASRDGETCPAFVSACSCSSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKG 1108
            PA   G   P      S      G PGP GPPG  GR+G  G  G PG  GPPG  G  G
Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG 1146


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,988,410
Number of Sequences: 37866
Number of extensions: 3872368
Number of successful extensions: 62059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 281
Number of HSP's successfully gapped in prelim test: 589
Number of HSP's that attempted gapping in prelim test: 14284
Number of HSP's gapped (non-prelim): 8657
length of query: 1284
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1170
effective length of database: 13,930,794
effective search space: 16299028980
effective search space used: 16299028980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press