Guide to the Human Genome
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Search of human proteins with 11140823

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]            630   0.0  
gi|23238204 tumor necrosis factor receptor superfamily, member 1...   189   3e-48
gi|23238202 tumor necrosis factor receptor superfamily, member 1...   189   3e-48
gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]          65   5e-11
gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ...    56   3e-08
gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ...    56   3e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    49   4e-06
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    48   9e-06
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    48   1e-05
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    48   1e-05
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    46   5e-05
gi|14790170 tumor necrosis factor receptor superfamily, member 6...    43   3e-04
gi|4507585 tumor necrosis factor receptor superfamily, member 6b...    43   3e-04
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    41   0.001
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  40   0.002
gi|148886654 polydom [Homo sapiens]                                    39   0.006
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]            37   0.027
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    37   0.027
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    36   0.047
gi|68348711 tumor necrosis factor receptor superfamily, member 8...    35   0.079
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    35   0.10 
gi|46909600 a disintegrin and metalloproteinase domain 15 isofor...    34   0.14 
gi|46909594 a disintegrin and metalloproteinase domain 15 isofor...    34   0.14 
gi|23200025 tumor necrosis factor receptor superfamily, member 2...    34   0.14 
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    34   0.14 
gi|6912694 tumor necrosis factor receptor 13B [Homo sapiens]           34   0.18 
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             34   0.18 
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            34   0.18 
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    34   0.18 
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    34   0.18 

>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score =  630 bits (1624), Expect = 0.0
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQS 60
           MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQS
Sbjct: 1   MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQS 60

Query: 61  CITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAF 120
           CITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAF
Sbjct: 61  CITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAF 120

Query: 121 QLSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEA 180
           QLSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEA
Sbjct: 121 QLSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEA 180

Query: 181 DKTAKEESLFPVPPSKETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCT 240
           DKTAKEESLFPVPPSKETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCT
Sbjct: 181 DKTAKEESLFPVPPSKETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCT 240

Query: 241 SESHSHWVHSPIECTELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVPFEVPSP 297
           SESHSHWVHSPIECTELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVPFEVPSP
Sbjct: 241 SESHSHWVHSPIECTELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVPFEVPSP 297


>gi|23238204 tumor necrosis factor receptor superfamily, member 19
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score =  189 bits (480), Expect = 3e-48
 Identities = 86/196 (43%), Positives = 116/196 (59%)

Query: 2   DCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSC 61
           DC++ E+ D+ G CV C +CGPG ELSK+CG+G G DA C  C   R+K  WG  +C+ C
Sbjct: 33  DCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPC 92

Query: 62  ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAFQ 121
           + CAV+NR QK NC+ATS+A+CGDCLP FYRKT++ G QD EC+PC    P  E  CA +
Sbjct: 93  LDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASK 152

Query: 122 LSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEAD 181
           ++LV+  +    P++  L A++ S L    LA L L  +YCK+ F        L   +  
Sbjct: 153 VNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQ 212

Query: 182 KTAKEESLFPVPPSKE 197
               E S F  P   E
Sbjct: 213 YNGSELSCFDRPQLHE 228


>gi|23238202 tumor necrosis factor receptor superfamily, member 19
           isoform 1 precursor [Homo sapiens]
          Length = 423

 Score =  189 bits (480), Expect = 3e-48
 Identities = 86/196 (43%), Positives = 116/196 (59%)

Query: 2   DCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSC 61
           DC++ E+ D+ G CV C +CGPG ELSK+CG+G G DA C  C   R+K  WG  +C+ C
Sbjct: 33  DCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPC 92

Query: 62  ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAFQ 121
           + CAV+NR QK NC+ATS+A+CGDCLP FYRKT++ G QD EC+PC    P  E  CA +
Sbjct: 93  LDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASK 152

Query: 122 LSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEAD 181
           ++LV+  +    P++  L A++ S L    LA L L  +YCK+ F        L   +  
Sbjct: 153 VNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQ 212

Query: 182 KTAKEESLFPVPPSKE 197
               E S F  P   E
Sbjct: 213 YNGSELSCFDRPQLHE 228


>gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]
          Length = 448

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 43/133 (32%), Positives = 60/133 (45%), Gaps = 6/133 (4%)

Query: 2   DCQENEYWDQW-GRCVTCQRCGPGQELSKDCGYGEGGDAY-CTACPPRRYKSSWGHHRCQ 59
           +C ENEY++Q  G C  C  CGPG+E    CGYG   + Y C  CP  ++ S  G+  C+
Sbjct: 30  NCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKF-SKGGYQICR 88

Query: 60  SCITCAVINRVQKVNCTATSN-AVCGDCLPRFYR-KTRIGGLQDQECIPCTKQTPTSEVQ 117
               C    R   +      N A CG CLP +Y  + R   +    C  C    P ++ +
Sbjct: 89  RHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTK-E 147

Query: 118 CAFQLSLVEADAP 130
           C    S   A+ P
Sbjct: 148 CVGATSGASANFP 160


>gi|23238200 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 17  TCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCT 76
           T  +C PG+E   D G G      C  CPP  + ++WG   CQ    C++  R++     
Sbjct: 28  TLWQCPPGEEPDLDPGQG----TLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGM 83

Query: 77  ATSNAVCGDCLPRFYRKTRIGGLQDQECIPCT 108
           AT + +CGDC P ++      G+    C PC+
Sbjct: 84  ATRDTLCGDCWPGWFGP---WGVPRVPCQPCS 112


>gi|21361873 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 29/92 (31%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 17  TCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCT 76
           T  +C PG+E   D G G      C  CPP  + ++WG   CQ    C++  R++     
Sbjct: 28  TLWQCPPGEEPDLDPGQG----TLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGM 83

Query: 77  ATSNAVCGDCLPRFYRKTRIGGLQDQECIPCT 108
           AT + +CGDC P ++      G+    C PC+
Sbjct: 84  ATRDTLCGDCWPGWFGP---WGVPRVPCQPCS 112


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 39/107 (36%), Positives = 43/107 (40%), Gaps = 15/107 (14%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCI 62
           C E  YW Q   C  CQ C PG  L KDC       A C  C P     S  HH    C 
Sbjct: 27  CPERHYWAQGKLC--CQMCEPGTFLVKDCDQHRKA-AQCDPCIP-GVSFSPDHHTRPHCE 82

Query: 63  TCAVINRVQKV-NCTATSNAVCGDCLPRFYRKTRIG-GLQDQECIPC 107
           +C   N    V NCT T+NA C           R G   +D+EC  C
Sbjct: 83  SCRHCNSGLLVRNCTITANAECA---------CRNGWQCRDKECTEC 120


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 72/309 (23%), Positives = 107/309 (34%), Gaps = 65/309 (21%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHR-CQSC 61
           C + +Y       + C +C  G  L  DC  G G D  C  C    + +S  H R C SC
Sbjct: 44  CPQGKYIHPQNNSICCTKCHKGTYLYNDCP-GPGQDTDCRECESGSFTASENHLRHCLSC 102

Query: 62  ITC-AVINRVQKVNCTATSNAVCGDCLPRFYR-------------KTRIGG--------- 98
             C   + +V+  +CT   + VCG C    YR                + G         
Sbjct: 103 SKCRKEMGQVEISSCTVDRDTVCG-CRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEK 161

Query: 99  ------------LQDQECIPCTKQTPTSEVQCAFQLSLVEADAPTVPPQEATLVALVSSL 146
                       L++ EC+ C+    + E     +L L + +         T V L   L
Sbjct: 162 QNTVCTCHAGFFLRENECVSCSNCKKSLE---CTKLCLPQIENVKGTEDSGTTVLL--PL 216

Query: 147 LVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEADKTAKEESLFPVPPSKETSAESQVSE 206
           ++ F L  L L F+     + R   +  L      K+          P KE   E     
Sbjct: 217 VIFFGLCLLSLLFIGLMYRYQR--WKSKLYSIVCGKST---------PEKEGELEGTT-- 263

Query: 207 NIFQTQPLNPILEDDCSSTSGF-PTQESFTMASCTSESHSHWVHSPIECTELDLQKFSSS 265
               T+PL P      S T GF PT     + S T  S S   ++P +C      +   +
Sbjct: 264 ----TKPLAP--NPSFSPTPGFTPTLGFSPVPSSTFTSSS--TYTPGDCPNFAAPRREVA 315

Query: 266 ASYTGAETL 274
             Y GA+ +
Sbjct: 316 PPYQGADPI 324


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/131 (29%), Positives = 52/131 (39%), Gaps = 24/131 (18%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSC 61
           C+  EY+DQ  + + C +C PGQ     C   +  D  C +C    Y   W     C SC
Sbjct: 40  CRLREYYDQTAQ-MCCSKCSPGQHAKVFCT--KTSDTVCDSCEDSTYTQLWNWVPECLSC 96

Query: 62  ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQE----CIPCTKQTP----- 112
            +    ++V+   CT   N +C  C P +Y       L  QE    C P  K  P     
Sbjct: 97  GSRCSSDQVETQACTREQNRIC-TCRPGWY-----CALSKQEGCRLCAPLRKCRPGFGVA 150

Query: 113 -----TSEVQC 118
                TS+V C
Sbjct: 151 RPGTETSDVVC 161



 Score = 28.1 bits (61), Expect = 9.7
 Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 7/76 (9%)

Query: 42  TACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQD 101
           + C  R Y        C  C       +  KV CT TS+ VC  C    Y  T++     
Sbjct: 38  STCRLREYYDQTAQMCCSKCSP----GQHAKVFCTKTSDTVCDSCEDSTY--TQLWNWV- 90

Query: 102 QECIPCTKQTPTSEVQ 117
            EC+ C  +  + +V+
Sbjct: 91  PECLSCGSRCSSDQVE 106


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 38/118 (32%), Positives = 51/118 (43%), Gaps = 14/118 (11%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSW-GHHRCQSC 61
           C+E+EY      C  C +C PG  + + CG   G    C  CPP  Y +   G  +C  C
Sbjct: 42  CKEDEY-PVGSEC--CPKCSPGYRVKEACGELTG--TVCEPCPPGTYIAHLNGLSKCLQC 96

Query: 62  ITC--AVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQ 117
             C  A+  R  + NC+ T NAVCG C P  +   + G      C  C     +S  Q
Sbjct: 97  QMCDPAMGLRASR-NCSRTENAVCG-CSPGHFCIVQDG----DHCAACRAYATSSPGQ 148



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 16/56 (28%), Positives = 20/56 (35%), Gaps = 2/56 (3%)

Query: 10  DQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCA 65
           D    C       PGQ + K  G  E  D  C  CPP  +  +     CQ    C+
Sbjct: 133 DHCAACRAYATSSPGQRVQK--GGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCS 186


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 78/339 (23%), Positives = 120/339 (35%), Gaps = 68/339 (20%)

Query: 4   QENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHR-CQSCI 62
           QE EY++   R + C RC PG  +S  C      D  C  C    Y   W +   CQ C 
Sbjct: 46  QEKEYYEPQHR-ICCSRCPPGTYVSAKC--SRIRDTVCATCAENSYNEHWNYLTICQLCR 102

Query: 63  TCAVINRVQKV-NCTATSNAVC---------------------GDCLPRFYRKTRIG-GL 99
            C  +  ++++  CT+     C                      DC P    + +   G 
Sbjct: 103 PCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGK 162

Query: 100 QDQECIPC------TKQTPTSEVQ----CAFQLSLVEAD--------------APTVPPQ 135
            +  C+PC         +P++  Q    C  Q  LVEA                P  P  
Sbjct: 163 GNNHCVPCKAGHFQNTSSPSARCQPHTRCENQ-GLVEAAPGTAQSDTTCKNPLEPLPPEM 221

Query: 136 EATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEADKTAKEESLFPVPPS 195
             T++ L   L + F L    +F    K   +   + G LL+    +  + E   PV  S
Sbjct: 222 SGTMLMLAVLLPLAFFLLLATVFSCIWKSHPSLCRKLGSLLK----RRPQGEGPNPVAGS 277

Query: 196 KETSAESQVSENIFQTQPLNPILEDDCSSTSGFPTQESFTMASCTSESHSHWVHSPIECT 255
            E         ++   QPL PI  D    ++G P       A+   E+      SP++ T
Sbjct: 278 WEPPKAHPYFPDL--VQPLLPISGDVSPVSTGLP-------AAPVLEAGVPQQQSPLDLT 328

Query: 256 ---ELDLQKFSSSASYTGAETLGGNTVESTGDRLELNVP 291
              +L+  + S  A  T    + G ++  TG+    N P
Sbjct: 329 REPQLEPGEQSQVAHGTNGIHVTGGSMTITGNIYIYNGP 367


>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 9/111 (8%)

Query: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSCITCAVINRVQ 71
           G  + C +C PG  + + C         C  CPPR Y   W +  RC+ C         +
Sbjct: 44  GERLVCAQCPPGTFVQRPCR--RDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE 101

Query: 72  KVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIP----CTKQTPTSEVQC 118
              C AT N  C  C   F+       L+   C P        TP+   QC
Sbjct: 102 ARACHATHNRAC-RCRTGFFAHAGF-CLEHASCPPGAGVIAPGTPSQNTQC 150


>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
           [Homo sapiens]
          Length = 300

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/111 (27%), Positives = 40/111 (36%), Gaps = 9/111 (8%)

Query: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRCQSCITCAVINRVQ 71
           G  + C +C PG  + + C         C  CPPR Y   W +  RC+ C         +
Sbjct: 44  GERLVCAQCPPGTFVQRPCR--RDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEE 101

Query: 72  KVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIP----CTKQTPTSEVQC 118
              C AT N  C  C   F+       L+   C P        TP+   QC
Sbjct: 102 ARACHATHNRAC-RCRTGFFAHAGF-CLEHASCPPGAGVIAPGTPSQNTQC 150


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 8/85 (9%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHH-RC--- 58
           C   ++++  GRC  C +C PG+ +S  C      D+ C  C P  Y  SW    +C   
Sbjct: 34  CTSEKHYEHLGRC--CNKCEPGKYMSSKCT--TTSDSVCLPCGPDEYLDSWNEEDKCLLH 89

Query: 59  QSCITCAVINRVQKVNCTATSNAVC 83
           + C T   +  V   N T      C
Sbjct: 90  KVCDTGKALVAVVAGNSTTPRRCAC 114



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 21/90 (23%), Positives = 34/90 (37%), Gaps = 8/90 (8%)

Query: 3   CQENEYWDQWGRCVTCQR---CGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH-HRC 58
           C    +W Q   C  C+R   C PG          +  D  C  C    +  ++    +C
Sbjct: 114 CTAGYHWSQ--DCECCRRNTECAPGLGAQHPLQLNK--DTVCKPCLAGYFSDAFSSTDKC 169

Query: 59  QSCITCAVINRVQKVNCTATSNAVCGDCLP 88
           +    C  + +  + + T  S+AVC   LP
Sbjct: 170 RPWTNCTFLGKRVEHHGTEKSDAVCSSSLP 199


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 7/79 (8%)

Query: 8   YWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCA-V 66
           Y ++    + C +C PG  L + C         C  CP   Y  SW  H    C+ C+ V
Sbjct: 31  YDEETSHQLLCDKCPPGTYLKQHC--TAKWKTVCAPCPDHYYTDSW--HTSDECLYCSPV 86

Query: 67  INRVQ--KVNCTATSNAVC 83
              +Q  K  C  T N VC
Sbjct: 87  CKELQYVKQECNRTHNRVC 105


>gi|148886654 polydom [Homo sapiens]
          Length = 3571

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 22/74 (29%), Positives = 29/74 (39%)

Query: 10  DQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINR 69
           D+ G C      G  + + +   YG+G    CTACP   YK         SCI C   N 
Sbjct: 289 DRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENH 348

Query: 70  VQKVNCTATSNAVC 83
                 T+  + VC
Sbjct: 349 TSPPGSTSPEDCVC 362



 Score = 28.1 bits (61), Expect = 9.7
 Identities = 19/73 (26%), Positives = 27/73 (36%), Gaps = 15/73 (20%)

Query: 3    CQENEYWDQWGRCVTCQRCGPGQELS-------KDCG-------YGEGGDAYCTACPPRR 48
            C+   Y D+ G+ + C+ C  G            DC        Y   G   C +CP   
Sbjct: 1018 CRIGSYQDEEGQ-LECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGT 1076

Query: 49   YKSSWGHHRCQSC 61
            Y+  +G   C SC
Sbjct: 1077 YQPKFGSRSCLSC 1089


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 21/98 (21%)

Query: 11  QWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRV 70
           +W   V   RC PG + ++       GD  C ACP   YKSS G+  C  C         
Sbjct: 291 KWMVAVGGCRCQPGYQPAR-------GDKACQACPRGLYKSSAGNAPCSPC--------P 335

Query: 71  QKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCT 108
            + +    +  VC  CL  FYR +      D    PCT
Sbjct: 336 ARSHAPNPAAPVC-PCLEGFYRAS-----SDPPEAPCT 367


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 58  CQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPT---- 113
           CQ C+ C  ++R  ++ C+      CG CLP FY            C+ C    P+    
Sbjct: 138 CQPCLDCGALHRHTRLLCSRRDTD-CGTCLPGFYE-------HGDGCVSCPTPPPSLAGA 189

Query: 114 --SEVQCAFQLSLVEADAPTVPPQEATLVALVSSLLVVFTLAF 154
               VQ A  LS V      V   +  L  LV  LL+  TL +
Sbjct: 190 PWGAVQSAVPLS-VAGGRVGVFWVQVLLAGLVVPLLLGATLTY 231


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 35.8 bits (81), Expect = 0.047
 Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 13/82 (15%)

Query: 58  CQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTS--- 114
           CQ C+ C  ++R  ++ C+      CG CLP FY            C+ C   T  S   
Sbjct: 138 CQPCLDCGALHRHTRLLCSRRDTD-CGTCLPGFYE-------HGDGCVSCPTSTLGSCPE 189

Query: 115 --EVQCAFQLSLVEADAPTVPP 134
                C ++ +    +A T PP
Sbjct: 190 RCAAVCGWRQNEAGMEALTPPP 211


>gi|68348711 tumor necrosis factor receptor superfamily, member 8
           isoform 1 precursor [Homo sapiens]
          Length = 595

 Score = 35.0 bits (79), Expect = 0.079
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 9/108 (8%)

Query: 23  PGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAV 82
           PG   ++ C  G G       C P  Y    G  RC +C++C+  + V+K  C   S+  
Sbjct: 225 PGLSPTQPCPEGSGDCR--KQCEPDYYLDEAG--RCTACVSCSRDDLVEKTPCAWNSSRT 280

Query: 83  CGDCLPRFYRKTRIGGLQDQECIP---CTKQTPTSEVQCAFQLSLVEA 127
           C +C P     T     +   C+P   C  +T T     A + +  EA
Sbjct: 281 C-ECRPGMICATSATNSR-ARCVPYPICAAETVTKPQDMAEKDTTFEA 326



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 14  RCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKV 73
           RC  C RC  G   ++ C   +        C P  Y       RC +C+TC+  + V+K 
Sbjct: 43  RC--CYRCPMGLFPTQQCP--QRPTDCRKQCEPDYYLDE--ADRCTACVTCSRDDLVEKT 96

Query: 74  NCTATSNAVCGDCLPRFYRKT 94
            C   S+ VC +C P  +  T
Sbjct: 97  PCAWNSSRVC-ECRPGMFCST 116



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/89 (24%), Positives = 33/89 (37%), Gaps = 6/89 (6%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSK-DCGYGEGGDAYCTACPPRRYKSSWGHHRCQSC 61
           C+ + Y D+  RC  C  C     + K  C +     +    C P  + S+   + C  C
Sbjct: 69  CEPDYYLDEADRCTACVTCSRDDLVEKTPCAW---NSSRVCECRPGMFCSTSAVNSCARC 125

Query: 62  ITCAV--INRVQKVNCTATSNAVCGDCLP 88
              +V     + K   TA  N VC    P
Sbjct: 126 FFHSVCPAGMIVKFPGTAQKNTVCEPASP 154


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 21/117 (17%)

Query: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRY-KSSWGHHRCQSCITCAVINRVQ 71
           G+ +TC +C  G  +S+ C         C++CP   + +   G  +C  C        ++
Sbjct: 62  GQVLTCDKCPAGTYVSEHC--TNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIE 119

Query: 72  KVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCT----------KQTPTSEVQC 118
           K+ C A ++  C  C P  ++        +  C P T          K T T +V+C
Sbjct: 120 KLPCAALTDREC-TCPPGMFQ-------SNATCAPHTVCPVGWGVRKKGTETEDVRC 168


>gi|46909600 a disintegrin and metalloproteinase domain 15 isoform 6
           preproprotein [Homo sapiens]
          Length = 863

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 142 LVSSLLVVFTLAFLGLFFLYCKQFFNRHCQ-RGGLLQFEADKTAKEESLFPVPPSKETSA 200
           L+ SLLV+  L  LG  + Y  +   R CQ +G   Q+ A ++   E   P PP +   A
Sbjct: 698 LLLSLLVLLVLVMLGASYWYRARLHQRLCQLKGPTCQYRAAQSGPSER--PGPPQRALLA 755

Query: 201 E--SQVSENIFQTQPLNPILEDDCS 223
               Q S   F   P  P+  D  S
Sbjct: 756 RGTKQASALSFPAPPSRPLPPDPVS 780


>gi|46909594 a disintegrin and metalloproteinase domain 15 isoform 3
           preproprotein [Homo sapiens]
          Length = 839

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 5/85 (5%)

Query: 142 LVSSLLVVFTLAFLGLFFLYCKQFFNRHCQ-RGGLLQFEADKTAKEESLFPVPPSKETSA 200
           L+ SLLV+  L  LG  + Y  +   R CQ +G   Q+ A ++   E   P PP +   A
Sbjct: 698 LLLSLLVLLVLVMLGASYWYRARLHQRLCQLKGPTCQYRAAQSGPSER--PGPPQRALLA 755

Query: 201 E--SQVSENIFQTQPLNPILEDDCS 223
               Q S   F   P  P+  D  S
Sbjct: 756 RGTKQASALSFPAPPSRPLPPDPVS 780


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 8/54 (14%)

Query: 58  CQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQT 111
           CQ C+ C  ++R  ++ C+      CG CLP FY            C+ C   T
Sbjct: 93  CQPCLDCGALHRHTRLLCSRRDTD-CGTCLPGFYE-------HGDGCVSCPTST 138


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 34.3 bits (77), Expect = 0.14
 Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 8/54 (14%)

Query: 58  CQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQT 111
           CQ C+ C  ++R  ++ C+      CG CLP FY            C+ C   T
Sbjct: 138 CQPCLDCGALHRHTRLLCSRRDTD-CGTCLPGFYE-------HGDGCVSCPTST 183


>gi|6912694 tumor necrosis factor receptor 13B [Homo sapiens]
          Length = 293

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 3  CQENEYWDQW-GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSC 61
          C E +YWD   G C++C+     Q   + C       A+C +   R+ +  +  H  + C
Sbjct: 34 CPEEQYWDPLLGTCMSCKTICNHQS-QRTCA------AFCRSLSCRKEQGKFYDHLLRDC 86

Query: 62 ITCAVI 67
          I+CA I
Sbjct: 87 ISCASI 92


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 26/126 (20%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWG-------H 55
           C+E +Y     +C  C  C PGQ+L  DC   E  +  C  C    +  +W        H
Sbjct: 26  CREKQYLIN-SQC--CSLCQPGQKLVSDC--TEFTETECLPCGESEFLDTWNRETHCHQH 80

Query: 56  HRCQSCI-----------TCAVINRVQKVNCTATSNAVC---GDCLPRFYRKTRIGGLQD 101
             C   +           T  +    +  +CT+ +   C     C P F  K    G+ D
Sbjct: 81  KYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSD 140

Query: 102 QECIPC 107
             C PC
Sbjct: 141 TICEPC 146


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 26/126 (20%)

Query: 3   CQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWG-------H 55
           C+E +Y     +C  C  C PGQ+L  DC   E  +  C  C    +  +W        H
Sbjct: 26  CREKQYLIN-SQC--CSLCQPGQKLVSDC--TEFTETECLPCGESEFLDTWNRETHCHQH 80

Query: 56  HRCQSCI-----------TCAVINRVQKVNCTATSNAVC---GDCLPRFYRKTRIGGLQD 101
             C   +           T  +    +  +CT+ +   C     C P F  K    G+ D
Sbjct: 81  KYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSD 140

Query: 102 QECIPC 107
             C PC
Sbjct: 141 TICEPC 146



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 29/121 (23%), Positives = 50/121 (41%), Gaps = 14/121 (11%)

Query: 1   MDCQENEYWDQWGRCVTCQR---CGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHR 57
           + C E+E+ D W R   C +   C P   L          D  CT C    + +S     
Sbjct: 60  LPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICT-CEEGWHCTS---EA 115

Query: 58  CQSCI---TCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTS 114
           C+SC+   +C+    V+++  T  S+ +C  C   F+          ++C P T+   ++
Sbjct: 116 CESCVLHRSCSPGFGVKQI-ATGVSDTICEPCPVGFFSNV---SSAFEKCHPWTRSPGSA 171

Query: 115 E 115
           E
Sbjct: 172 E 172


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 6/80 (7%)

Query: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH--HRCQSCITCAVINRV 70
           GRC+TC+    G +  + C  G  G+     CPP R   +  H   +C  C    + +R 
Sbjct: 300 GRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRC 359

Query: 71  QKVNCTATSNA----VCGDC 86
           +      T       VC DC
Sbjct: 360 ETKCSNGTYGEDCAFVCADC 379


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 6/80 (7%)

Query: 13  GRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGH--HRCQSCITCAVINRV 70
           GRC+TC+    G +  + C  G  G+     CPP R   +  H   +C  C    + +R 
Sbjct: 300 GRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRC 359

Query: 71  QKVNCTATSNA----VCGDC 86
           +      T       VC DC
Sbjct: 360 ETKCSNGTYGEDCAFVCADC 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,098,580
Number of Sequences: 37866
Number of extensions: 604597
Number of successful extensions: 2152
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 2026
Number of HSP's gapped (non-prelim): 183
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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