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Search of human proteins with 165932370
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
(4981 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 9948 0.0
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 1262 0.0
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 1242 0.0
gi|16933557 dachsous 1 precursor [Homo sapiens] 1152 0.0
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 1070 0.0
gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens] 1061 0.0
gi|47059046 dachsous 2 isoform 1 [Homo sapiens] 863 0.0
gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo ... 598 e-170
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 598 e-170
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s... 574 e-163
gi|216548385 dachsous 2 isoform 2 [Homo sapiens] 503 e-141
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 354 1e-96
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 354 1e-96
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 343 2e-93
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 343 2e-93
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 343 3e-93
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 343 3e-93
gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapi... 343 3e-93
gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapi... 343 3e-93
gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapi... 343 3e-93
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 343 3e-93
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 343 3e-93
gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi... 343 3e-93
gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi... 343 3e-93
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 338 6e-92
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 332 6e-90
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 329 5e-89
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 329 5e-89
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 329 5e-89
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 325 7e-88
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 9948 bits (25815), Expect = 0.0
Identities = 4981/4981 (100%), Positives = 4981/4981 (100%)
Query: 1 MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTL 60
MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTL
Sbjct: 1 MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTL 60
Query: 61 VGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTE 120
VGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTE
Sbjct: 61 VGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTE 120
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN
Sbjct: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
Query: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV
Sbjct: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
Query: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDP 300
QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDP
Sbjct: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDP 300
Query: 301 ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPA 360
ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPA
Sbjct: 301 ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPA 360
Query: 361 TSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLI 420
TSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLI
Sbjct: 361 TSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLI 420
Query: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY
Sbjct: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
Query: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGL 540
RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGL
Sbjct: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGL 540
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT
Sbjct: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL 660
ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL
Sbjct: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL 660
Query: 661 ATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGT 720
ATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGT
Sbjct: 661 ATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGT 720
Query: 721 NGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVT 780
NGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVT
Sbjct: 721 NGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVT 780
Query: 781 ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA
Sbjct: 781 ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESV 900
INQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESV
Sbjct: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESV 900
Query: 901 NVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAG 960
NVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAG
Sbjct: 901 NVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAG 960
Query: 961 SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQA 1020
SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQA
Sbjct: 961 SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQA 1020
Query: 1021 SDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPL 1080
SDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPL
Sbjct: 1021 SDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPL 1080
Query: 1081 SATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE 1140
SATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE
Sbjct: 1081 SATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE 1140
Query: 1141 MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYM 1200
MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYM
Sbjct: 1141 MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYM 1200
Query: 1201 KDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAI 1260
KDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAI
Sbjct: 1201 KDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAI 1260
Query: 1261 DSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTL 1320
DSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTL
Sbjct: 1261 DSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTL 1320
Query: 1321 FVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDF 1380
FVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDF
Sbjct: 1321 FVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDF 1380
Query: 1381 ETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVI 1440
ETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVI
Sbjct: 1381 ETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVI 1440
Query: 1441 SVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKAND 1500
SVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKAND
Sbjct: 1441 SVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKAND 1500
Query: 1501 QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGAN 1560
QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGAN
Sbjct: 1501 QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGAN 1560
Query: 1561 GEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTII 1620
GEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTII
Sbjct: 1561 GEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTII 1620
Query: 1621 LQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRL 1680
LQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRL
Sbjct: 1621 LQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRL 1680
Query: 1681 FTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVF 1740
FTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVF
Sbjct: 1681 FTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVF 1740
Query: 1741 PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATR 1800
PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATR
Sbjct: 1741 PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATR 1800
Query: 1801 RLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLV 1860
RLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLV
Sbjct: 1801 RLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLV 1860
Query: 1861 AAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAED 1920
AAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAED
Sbjct: 1861 AAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAED 1920
Query: 1921 GGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT 1980
GGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT
Sbjct: 1921 GGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT 1980
Query: 1981 YSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSII 2040
YSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSII
Sbjct: 1981 YSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSII 2040
Query: 2041 LLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
LLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG
Sbjct: 2041 LLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
Query: 2101 TIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYK 2160
TIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYK
Sbjct: 2101 TIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYK 2160
Query: 2161 VEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDRE 2220
VEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDRE
Sbjct: 2161 VEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDRE 2220
Query: 2221 KTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTIL 2280
KTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTIL
Sbjct: 2221 KTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTIL 2280
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG
Sbjct: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR
Sbjct: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
Query: 2401 IIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVN 2460
IIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVN
Sbjct: 2401 IIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVN 2460
Query: 2461 DNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRG 2520
DNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRG
Sbjct: 2461 DNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRG 2520
Query: 2521 AIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQ 2580
AIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQ
Sbjct: 2521 AIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQ 2580
Query: 2581 PVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIE 2640
PVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIE
Sbjct: 2581 PVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIE 2640
Query: 2641 ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPN 2700
ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPN
Sbjct: 2641 ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPN 2700
Query: 2701 GQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVM 2760
GQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVM
Sbjct: 2701 GQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVM 2760
Query: 2761 INILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTI 2820
INILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTI
Sbjct: 2761 INILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTI 2820
Query: 2821 NPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLD 2880
NPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLD
Sbjct: 2821 NPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLD 2880
Query: 2881 CPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTG 2940
CPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTG
Sbjct: 2881 CPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTG 2940
Query: 2941 FSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGT 3000
FSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGT
Sbjct: 2941 FSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGT 3000
Query: 3001 KLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVT 3060
KLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVT
Sbjct: 3001 KLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVT 3060
Query: 3061 AKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAM 3120
AKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAM
Sbjct: 3061 AKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAM 3120
Query: 3121 NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSV 3180
NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSV
Sbjct: 3121 NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSV 3180
Query: 3181 TVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDL 3240
TVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDL
Sbjct: 3181 TVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDL 3240
Query: 3241 FVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS 3300
FVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS
Sbjct: 3241 FVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS 3300
Query: 3301 KLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI 3360
KLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI
Sbjct: 3301 KLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI 3360
Query: 3361 LDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIG 3420
LDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIG
Sbjct: 3361 LDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIG 3420
Query: 3421 THVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSV 3480
THVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSV
Sbjct: 3421 THVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSV 3480
Query: 3481 LAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
LAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPN
Sbjct: 3481 LAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
Query: 3541 QGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTV 3600
QGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTV
Sbjct: 3541 QGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTV 3600
Query: 3601 HITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVTSLFS 3660
HITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVTSLFS
Sbjct: 3601 HITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVTSLFS 3660
Query: 3661 IPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVP 3720
IPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVP
Sbjct: 3661 IPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVP 3720
Query: 3721 TVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYEENNRTFLLAAVKRNHNQYVNPSGVA 3780
TVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYEENNRTFLLAAVKRNHNQYVNPSGVA
Sbjct: 3721 TVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYEENNRTFLLAAVKRNHNQYVNPSGVA 3780
Query: 3781 TFFESIKEILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVAN 3840
TFFESIKEILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVAN
Sbjct: 3781 TFFESIKEILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVAN 3840
Query: 3841 EPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERD 3900
EPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERD
Sbjct: 3841 EPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERD 3900
Query: 3901 INECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSY 3960
INECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSY
Sbjct: 3901 INECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSY 3960
Query: 3961 YCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTG 4020
YCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTG
Sbjct: 3961 YCHCPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTG 4020
Query: 4021 DRAEFLALEIAEERLRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSE 4080
DRAEFLALEIAEERLRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSE
Sbjct: 4021 DRAEFLALEIAEERLRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSE 4080
Query: 4081 NQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVN 4140
NQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVN
Sbjct: 4081 NQEPGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVN 4140
Query: 4141 GRPLEPSQALAAQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKS 4200
GRPLEPSQALAAQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKS
Sbjct: 4141 GRPLEPSQALAAQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKS 4200
Query: 4201 VTPDTALSLEGKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLI 4260
VTPDTALSLEGKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLI
Sbjct: 4201 VTPDTALSLEGKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLI 4260
Query: 4261 HIQESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSV 4320
HIQESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSV
Sbjct: 4261 HIQESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSV 4320
Query: 4321 DRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSG 4380
DRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSG
Sbjct: 4321 DRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSG 4380
Query: 4381 KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGS 4440
KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGS
Sbjct: 4381 KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRCVPPGDCASHPCQNGGS 4440
Query: 4441 CEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCVLSQGPEEISL 4500
CEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCVLSQGPEEISL
Sbjct: 4441 CEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCVLSQGPEEISL 4500
Query: 4501 PLWAVPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPD 4560
PLWAVPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPD
Sbjct: 4501 PLWAVPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPD 4560
Query: 4561 NIPPYGDDMTVRKQPEGNPKPDIIERENPYLIYDETDIPHNSETIPSAPLASPEQEIEHY 4620
NIPPYGDDMTVRKQPEGNPKPDIIERENPYLIYDETDIPHNSETIPSAPLASPEQEIEHY
Sbjct: 4561 NIPPYGDDMTVRKQPEGNPKPDIIERENPYLIYDETDIPHNSETIPSAPLASPEQEIEHY 4620
Query: 4621 DIDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPLGFARQSPMPLGASSLTYQPSYGQ 4680
DIDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPLGFARQSPMPLGASSLTYQPSYGQ
Sbjct: 4621 DIDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPLGFARQSPMPLGASSLTYQPSYGQ 4680
Query: 4681 GLRTSSLSHSACPTPNPLSRHSPAPFSKSSTFYRNSPARELHLPIRDGNTLEMHGDTCQP 4740
GLRTSSLSHSACPTPNPLSRHSPAPFSKSSTFYRNSPARELHLPIRDGNTLEMHGDTCQP
Sbjct: 4681 GLRTSSLSHSACPTPNPLSRHSPAPFSKSSTFYRNSPARELHLPIRDGNTLEMHGDTCQP 4740
Query: 4741 GIFNYATRLGRRSKSPQAMASHGSRPGSRLKQPIGQIPLESSPPVGLSIEEVERLNTPRP 4800
GIFNYATRLGRRSKSPQAMASHGSRPGSRLKQPIGQIPLESSPPVGLSIEEVERLNTPRP
Sbjct: 4741 GIFNYATRLGRRSKSPQAMASHGSRPGSRLKQPIGQIPLESSPPVGLSIEEVERLNTPRP 4800
Query: 4801 RNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSDSHESFTCSEMEYDREKP 4860
RNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSDSHESFTCSEMEYDREKP
Sbjct: 4801 RNPSICSADHGRSSSEEDCRRPLSRTRNPADGIPAPESSSDSDSHESFTCSEMEYDREKP 4860
Query: 4861 MVYTSRMPKLSQVNESDADDEDNYGARLKPRRYHGRRAEGGPVGTQAAAPGTADNTLPMK 4920
MVYTSRMPKLSQVNESDADDEDNYGARLKPRRYHGRRAEGGPVGTQAAAPGTADNTLPMK
Sbjct: 4861 MVYTSRMPKLSQVNESDADDEDNYGARLKPRRYHGRRAEGGPVGTQAAAPGTADNTLPMK 4920
Query: 4921 LGQQAGTFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAANEEGKAGTTKPVPKDGEAEQY 4980
LGQQAGTFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAANEEGKAGTTKPVPKDGEAEQY
Sbjct: 4921 LGQQAGTFNWDNLLNWGPGFGHYVDVFKDLASLPEKAAANEEGKAGTTKPVPKDGEAEQY 4980
Query: 4981 V 4981
V
Sbjct: 4981 V 4981
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 1262 bits (3265), Expect = 0.0
Identities = 1138/3894 (29%), Positives = 1806/3894 (46%), Gaps = 317/3894 (8%)
Query: 174 YRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGG----LDREVTPQYQLLVEVEDKGEPK 229
YRI+ G+E G F+ + + + FL + +KGG L+RE+ Y L+V+ +GE
Sbjct: 81 YRIVSGDEEGFFKAEEVI--IADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDL 138
Query: 230 RRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL 289
+ +VN+ V D+ND P+F + Y + E + +SV QV A DAD G+N + Y
Sbjct: 139 E-AWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYF 197
Query: 290 QDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVP-----SLTGRAEALIQLL 344
+++ F + P +G+I++ L+++ + +Y L + A+DRG+ ++ A+ + +
Sbjct: 198 KNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIE 257
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNI-SVQILGGNE 403
+N++ P + V + + A++TV D D ANG I SV I+ G+
Sbjct: 258 RINEHAPTIHV--------VTHVPFSLEKEPTYAVVTVDDLDD-GANGEIESVSIVAGDP 308
Query: 404 -QRHFEVQSSKVPNLSLIKVASALDRERIP-SYNLTVSVSDNYGAPPGAAVQARSSVASL 461
+ F + K N IK +D E P YNLT+ D G+P + S
Sbjct: 309 LDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDK-GSPQ------KCSALKA 361
Query: 462 VIFVNDINDHPPV-FSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGL 520
V N D P+ F ++VY V++SE +PPG V+ + + ++ Y + G
Sbjct: 362 VYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEP----IDVEYKLSPGEDA 417
Query: 521 GWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKP 580
+F I+ SGL+ T L+ L ++ ++ + AQ+ +++ D ND P
Sbjct: 418 VYFKINPRSGLIVTARP--LNTVKKEVYKLEVTNKEGDLK-----AQVTISIEDANDHTP 470
Query: 581 VFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGR 640
F QP YD V E+ P GT +L + A+D D G+NG + +S+ A + F ++ +G
Sbjct: 471 EFQQPL-YDAYVNESVPVGTSVLTVSASDKDKGENGYITYSI--ASLNLLPFVINQFTGV 527
Query: 641 LSTISSLDREEQA-FYSLLVLATDLGSPPQ-SSMARINVSLLDINDNSPVFYPVQYFAHI 698
+ST LD E Y +V A+D GSP + S + + + ++NDNSP+F V I
Sbjct: 528 ISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVI 587
Query: 699 KENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDRE--E 755
+ P G +IT VSA D D VKY I +G+ F +N SGV+ + +L +
Sbjct: 588 SYDFPVGGHITAVSAIDID--ELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIK 645
Query: 756 KTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFS----QVA-------------- 797
+ L+I ATDG NL P + I+VL + + FS +VA
Sbjct: 646 NGNFALRITATDGENLADPMS--INISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKAN 703
Query: 798 ------------YSF---------------VVFENVALGYHVGSVSASTMD--LNSNISY 828
YS V E++ +G ++ + A D N + +
Sbjct: 704 GKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLF 763
Query: 829 LITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA---SGGTVTGDTMVNITVKD 885
I+ G+ F I+ TGQL +DRE Y L + + ++ I V+D
Sbjct: 764 TISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVED 823
Query: 886 LNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEK 945
NDNSP F+Q SVN++E+ G I Q +A D D G NG V YS+ + + FAIN
Sbjct: 824 ANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQ-FAINSS 882
Query: 946 NGTISLLGPLDVHA-GSYQIEILASDMGVP--QLSSSVILTVYVHDVNDNSPVFDQLSYE 1002
G + + LD + +Y ++I A D QL S V L V++ DVND SP F SY
Sbjct: 883 TGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYS 942
Query: 1003 VTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDREL 1062
V + E PV + ++ D D G G++ Y++ G G + + ELD E
Sbjct: 943 VKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEK 1002
Query: 1063 QDRYVLMVVASDRAVE-PLSATVNVTVILEDVNDN--RPLFNSTNYTFYFEEEQRAGSFV 1119
Q Y L V A D+ LS+ V V + DVN+N P F +E R G+ V
Sbjct: 1003 QQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSV 1062
Query: 1120 GKVSAVDKDFGPNGEVRYSFEMVQP--DFELHAISGEITNTHQFDRESLMRRRGTAVFSF 1177
+V+A D+D G +GE++YS F + SG IT DRE++ +
Sbjct: 1063 LQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETM------GSYWL 1116
Query: 1178 TVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDV 1237
TV ATD+G+ PL V++ ++D+NDNAP + Y + E++ V+++ A D
Sbjct: 1117 TVYATDRGVV-PLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDP 1175
Query: 1238 DEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIG-KLDYEATPAYSLVIQAVDSGTIPLN 1296
D +N + Y I GN + FAI+ +G +T KLD E + L + D G P
Sbjct: 1176 DSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQ 1235
Query: 1297 STCTLNIDILDENDNTPSFPKSTLFVDVLENMRI--GELVSSVTATDSDSGDNADLYYSI 1354
ST + + +LDENDN P FP+ + + E R GE + A D D G NA++ YSI
Sbjct: 1236 STIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSI 1295
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFN 1414
N+ G F I P TG + K+ F S L I A D GRP +SST +H+
Sbjct: 1296 VDGNDDGKFFIDPKTGMVSSRKQ--FTAGSYDILTIKAVDNGRPQKSSTAR--LHIEWIK 1351
Query: 1415 DNPPSFPP----GDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH-- 1468
PPS P + V T ++ V + P N L + I+ GN
Sbjct: 1352 KPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQP---ANTPLWFDIVG----GNFDS 1404
Query: 1469 -FTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVP 1527
F ++ GTI +D E +++ ++V+ D A+ V I V D NDN P
Sbjct: 1405 AFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGT------NVAVTQVFIKVLDNNDNGP 1458
Query: 1528 MFISQNA-LAADPSAVIGSVLTTIMAADPDEG--ANGEIEYEIINGDTDTFIVDRYSGDL 1584
F N + + + + I A D DE + + I + F +D +G L
Sbjct: 1459 EFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVL 1518
Query: 1585 RVASAL---VPSQLIYNLIVSATDLGPERRKSTTELTIILQGLD-GPVFTQPKYITILKE 1640
A L + I N++V + P RR + + D P FT P Y + E
Sbjct: 1519 YTAERLDHEAQDKHILNIMVRDQEF-PYRRNLARVIVNVEDANDHSPYFTNPLYEASVFE 1577
Query: 1641 GEPIGTNVISIEAASP-RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDRE 1699
+G+ V+ + A +G A + Y I E G +F I GII D
Sbjct: 1578 SAALGSAVLQVTALDKDKGENAELIYTI-----EAGNTGNMFKIEPVLGIITICKEPDMT 1632
Query: 1700 QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKI 1759
L + S T + +T+ D N +P D V EN+ G+ +
Sbjct: 1633 TMGQFVLSIKVTDQGSPPMSATAIVRISVTMSD-NSHPKFIHKDY-QAEVNENVDIGTSV 1690
Query: 1760 MQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADD 1818
+ ++A+ + + + Y + G + F I+P SG + + LD ER S Y L+++A +
Sbjct: 1691 ILISAI-----SQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATN 1745
Query: 1819 GL-QSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAA-------ILATDDDS 1870
+S+ +NI + D ND+ P F YS + E S+V + I ATD DS
Sbjct: 1746 MAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADS 1805
Query: 1871 GVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT--- 1927
N + Y + E F ++ TG LD+E ++ V D G T
Sbjct: 1806 NRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAES 1865
Query: 1928 -IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
+ V + DVNDNPP+F+ + T L+ VG VL + TD D + +LTYS+ G
Sbjct: 1866 PVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEG 1925
Query: 1987 DSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVND 2046
SL F +D N + +K + S+ Y L+V+V D +F ST+ V+I++ + D
Sbjct: 1926 -SLDHFLIDSNSGVLTIKN-NNLSKDHYMLIVKVSD------GKFYSTSMVTIMVKEAMD 1977
Query: 2047 NPPTFL-SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE 2105
+ F S T I EN T V A + N ++Y++LNP GNKF I + G
Sbjct: 1978 SGLHFTQSFYSTSISENNTNITKVAIVNAVG--NRLNEPLKYSILNP-GNKFKIKSTSGV 2034
Query: 2106 VRLTG-ELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEIN 2164
++ TG DREE Y L V A+ + + V V + DINDN+P+F Y +
Sbjct: 2035 IQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQ 2094
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
+ GT I QV A D D+G NG+V Y V + F I+ +G + + + + + +
Sbjct: 2095 VDAEPGTLIYQVTAIDKDKGPNGEVTY--VLQDDYGHFEINPNSGNVILKEAFNSDLSNI 2152
Query: 2225 -YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV 2283
Y +T+ A D G P TS V + + +N +PVF+ Y+ +V E++ + IL +
Sbjct: 2153 EYGVTILAKD-GGKPSLSTS-VELPITIVNKAMPVFDKPFYTASVNEDI-RMNTPILSIN 2209
Query: 2284 ARDDDRGSNSKLSYVLFGGNEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSP 2342
A + + Y++ G+ F + +G L V LD E + L I A+D
Sbjct: 2210 ATSPE---GQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASD---- 2262
Query: 2343 ALTGTG---TINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI 2399
ALTG T++++V+DVNDN P F Y TT+ E + GT VL V + DAD+ N ++
Sbjct: 2263 ALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMV 2322
Query: 2400 RI------IGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVL 2453
F I+ S+G I+T+ +LD E + TL V D+G P LSS V
Sbjct: 2323 HYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPS-LSSEVLVH 2381
Query: 2454 VTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRNSEK 2512
+ ++DVNDNPP F Y +++ G FV V +DAD L YS LSG +
Sbjct: 2382 IYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTS 2441
Query: 2513 FHIDPLRGAIMAAGPLNGASEVTFSVHVK-DGGSFPKTDSTTVTVRFVNKADFPKVRAKE 2571
F +D G I + E +S++V G F T + V +R + A+ +
Sbjct: 2442 FLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLF--TSTAQVHIRVLG-ANLYSPAFSQ 2498
Query: 2572 QTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQL----TGQVSISQPL 2627
T++ + V++ I + G+P +Y S + N F D+ GQV ++ L
Sbjct: 2499 STYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITTERL 2558
Query: 2628 DFEKIQK--YVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR 2685
D E + +++ A DGG +++ + + V+D NDNAP F + + + ++
Sbjct: 2559 DRENPLEGDVSIFVRALDGGGR--TTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRG 2616
Query: 2686 KILT-VSAMDKDSGPNGQLDYEIVNG---NMENSFSINHATGEIRSVRPLDREKVSHYVL 2741
++T V A+D D G N ++ Y + + ++ + I+ G + + ++ K +
Sbjct: 2617 HLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSF 2676
Query: 2742 TIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVT--RVTTSD 2798
+K+ D G P + + + V I++L P F+Q +S + E++ +G TV R+ S
Sbjct: 2677 FVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQ 2736
Query: 2799 EDIGINAISRYSIMDASLP-------FTINPSTGDIVISRPLNREDTDRYRIRVSAH--- 2848
+S ++ P F I TG I + + L+RE + + +V+A
Sbjct: 2737 N-------VWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPL 2789
Query: 2849 ---DSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG 2905
D +TV DV I V D+NDN P F +SY E +G+K+TQV A D D G+NG
Sbjct: 2790 DKVDIVFTV--DVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANG 2847
Query: 2906 QVFYFIKSQS------EYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRG 2959
QV Y + S S E F I++ TG I + L ++ F+ F V +SD G
Sbjct: 2848 QVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFT--------FSVVASDLG 2899
Query: 2960 KP-SLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSE 3018
+ SL S V++ + D NDNAP F + Y V ++ G + ++ D +N +
Sbjct: 2900 EAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQ 2959
Query: 3019 VEYFISNDNHLGKFKLDN-DTGW-ISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVH 3076
V Y I+ N G+F L + W + V L + +F+ +TA D +QA V
Sbjct: 2960 VSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDG---LFVTQAMVE 3016
Query: 3077 ITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSI-SSGNEEG 3135
++V++ N ++P Q +A +PE I+ VSA+D D NG I+YS+ SGN E
Sbjct: 3017 VSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSE- 3075
Query: 3136 IFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVNDNSPV 3193
F ++ +G L LD E + + A DGG +C +++I DVNDN PV
Sbjct: 3076 -FFLDPESGELKTLALLDRERIPVYSLMAKATDGGG----RFCQSNIHLILEDVNDNPPV 3130
Query: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQ 3253
F SD Y V EN + + + A D D G N + Y++ S +F ID ++G+I +
Sbjct: 3131 FSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILE 3190
Query: 3254 GFLDFETKQSYHLTVKAFNV-PDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
LD E + SY+++V+A + P + S TV I + N+ P F + Y + E
Sbjct: 3191 QPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTS 3250
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
GT V VFA+ +D+GT+ E+ YLI + + F+IN KTG I VS +LD E +R L
Sbjct: 3251 PGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLV 3310
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDS 3431
V AK+ G+ + + TVN+ + D ND PP F+ ++YS ISE +G V + A D
Sbjct: 3311 VEAKDGGTPALSAV--ATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAEDV 3368
Query: 3432 DSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSAT 3491
DS P+ + + I +G+ + F+++P G + V +LDRE + Y+L V AVDSG P+ +
Sbjct: 3369 DSQPN-GQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMS 3427
Query: 3492 GSASLLVTLEDINDNGPMLTVSE--GEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL 3549
+A++ + + D+NDN P+ T + + ENK GT ++ L TD D N PF++ +L
Sbjct: 3428 STATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSIL 3487
Query: 3550 STGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
S G F L G+L + + ++ L V KDSG PQ S + + VI+++
Sbjct: 3488 S-GNEEEEFVLDPHGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEEST 3546
Query: 3610 NPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVTSLFSIPGGTCDLN 3669
+ + +EIF+ + FPGG++G + D D+ D +L S SLF + +
Sbjct: 3547 HKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKII 3606
Query: 3670 SQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNH 3729
+ G + L V +DG V ++ V + + N++ +R + +DF+ H
Sbjct: 3607 ALGGLDSGKYVLNVSVSDG-RFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLH 3665
Query: 3730 YLHFLR-IASSQLTGLGTAVQLYS--AYEENNRTFLLAAVKRNHNQYVNPSGVATFFESI 3786
F R + ++ LT ++++ S N+ +L AV+ + +++ P+ + +
Sbjct: 3666 MHGFRRTLRNAVLTQKQDSLRIISIQPVAGTNQLDMLFAVEMHSSEFYKPAYLIQKLSNA 3725
Query: 3787 K---EILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPL 3843
+ E ++R S + ++ C C+ G S S L + + + V
Sbjct: 3726 RRHLENIMRISAILEKNCSGLDCQEQHCEQGLS-----LDSHALMTYSTARISFVCPRFY 3780
Query: 3844 QPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGG---FSCSCPDGFTG 3894
+ C C G C D C+ PC C + F C CP G G
Sbjct: 3781 RNVRCTC----NGGLCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG 3830
Score = 1132 bits (2929), Expect = 0.0
Identities = 1011/3341 (30%), Positives = 1561/3341 (46%), Gaps = 247/3341 (7%)
Query: 51 VLEEQPPGTLVGTIQTRP---GFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDV 105
+ E PPG +V ++ P Y+LS E F IN +G + T ++ ++ +V
Sbjct: 385 ISEFSPPGVVVAIVKLSPEPIDVEYKLSPGEDAVYFKINPRSGLIVTARPLN--TVKKEV 442
Query: 106 INLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIG 165
L V + +V + + D ND+ P F P E G V+ +A+D D G
Sbjct: 443 YKLEVTNKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKG 502
Query: 166 SNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVS-KGGLDREVTPQ-YQLLVEVE 223
NG + +Y I + L P F ++S LD E +P+ Y+ +V
Sbjct: 503 ENG--YITYSI----------ASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRAS 550
Query: 224 DKGEPKRRGYLQVNVTVQ--DINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGT 281
D G P R +VNVT++ ++NDN P+F Q + D VG + V+A D DE
Sbjct: 551 DWGSPYRH-ESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELE 609
Query: 282 NADIRYRLQDEGTPFQMDPETGLITVREPLDFEARR--QYSLTVQAMDR---------GV 330
+ +E F ++P++G++ +++ L + ++L + A D +
Sbjct: 610 LVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINI 669
Query: 331 PSLTGR-------------AEALIQLL--------DVNDNDPVVKFRYFPATSRY----- 364
L G+ A+ L + L +N D + F Y
Sbjct: 670 SVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSF 729
Query: 365 ---ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIK 421
+V E+ VG + + DADS NG + I GN F + +K
Sbjct: 730 PSDVAVKEDLPVGANILKIKAYDADS-GFNGKVLFTISDGNTDSCFNIDM----ETGQLK 784
Query: 422 VASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYR 481
V +DRE Y L +++ D G P +SS L I V D ND+ PVF Q Y
Sbjct: 785 VLMPMDREHTDLYLLNITIYD-LGNP------QKSSWRLLTINVEDANDNSPVFIQDSYS 837
Query: 482 VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLD 541
VN+ E + G+ + + A D D G N + YS+++ F I+ +G+V LD
Sbjct: 838 VNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDT--QQFAINSSTGIVYVADQ--LD 893
Query: 542 RELASQIVLNISARDQGVHPK--VSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTG 599
RE + L I ARD+ + S L V L DVND P F P Y V V+E+ P G
Sbjct: 894 RESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFI-PSSYSVKVLEDLPVG 952
Query: 600 TELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLV 659
T + L D DLG G VR+SL R F +D SG + LD E+Q FY+L V
Sbjct: 953 TVIAWLETHDPDLGLGGQVRYSLVNDYNGR--FEIDKASGAIRLSKELDYEKQQFYNLTV 1010
Query: 660 LATDLGSPPQ-SSMARINVSLLDINDN--SPVFYPVQYFAHIKENEPGGSYITTVSATDP 716
A D G P SS++ + V ++D+N+N +P F +KEN G+ + V+A D
Sbjct: 1011 RAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDE 1070
Query: 717 DLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPN 775
D G +G ++YSI G RF ++ +SGVI+ LDRE +Y L + ATD G + +
Sbjct: 1071 DSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYS 1130
Query: 776 QAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTG 833
V I V D DN P+ S+ Y VV EN V + A D +SN ++Y IT+G
Sbjct: 1131 TIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSG 1190
Query: 834 DQKGMFAINQVTGQL-TTANVIDREEQSFYQLKV-VASGGTVTGDTMVNITVK--DLNDN 889
+ + FAIN TG + TT+ +DRE+Q+ + L+V V GG + + + V+ D NDN
Sbjct: 1191 NPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDN 1250
Query: 890 SPHFLQAIESVNVVE--NWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKN 946
P F + + + + E + G I++A A D DEG N + YS+ N F I+ K
Sbjct: 1251 KPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKT 1310
Query: 947 GTISLLGPLDVHAGSYQI-EILASDMGVPQLSSSVILTVYVHDVNDNSPV---FDQLSYE 1002
G +S AGSY I I A D G PQ SS+ L + SP+ FD+ Y
Sbjct: 1311 GMVS--SRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYN 1368
Query: 1003 VTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRE 1061
T+ ES+ V V AN + + I GN AF G + I LD E
Sbjct: 1369 FTVMESDRVTEIVGVVSVQP----ANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAE 1424
Query: 1062 LQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGK 1121
+ Y + V +D A V + + D NDN P F+ NY E+ + + +
Sbjct: 1425 QRSIYNMSVEVTDGT---NVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQ 1481
Query: 1122 VSAVDKD--FGPNGEVRYSFEMV-QPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFT 1178
+ A D+D + V S + + F + +G + + D E+ +
Sbjct: 1482 IEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKH------ILN 1535
Query: 1179 VIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVD 1238
++ DQ P ++ A V V ++D ND++P F Y+A++ ESAA + VL+V+A D D
Sbjct: 1536 IMVRDQEFPY-RRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKD 1594
Query: 1239 EGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNST 1298
+G N + Y+I GN F I+ G +T+ + D + L I+ D G+ P+++T
Sbjct: 1595 KGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSAT 1654
Query: 1299 CTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTN 1358
+ I + +++ P F +V EN+ IG V ++A + L Y + +
Sbjct: 1655 AIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQST-----LIYEVKDGD 1709
Query: 1359 NHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPP 1418
+G F+I+P +G I K LD+E S Y+L I A + +S +V I + D NDN P
Sbjct: 1710 INGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMA--GMASNATVNIQIVDENDNAP 1767
Query: 1419 SFPPGDIFKSIVENIPIGTSVIS-------VTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
F S+ E PI + V S + A D D++ N L Y I++ + FT+
Sbjct: 1768 VFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAK-KFFTV 1826
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
D G I T A +D E F V D P T ++ V I VTD+NDN P+F
Sbjct: 1827 DSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVE-VNIEVTDVNDNPPVFTQ 1885
Query: 1532 Q--NALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASA 1589
+ P+ +G + + A DPD E+ Y ++ G D F++D SG L + +
Sbjct: 1886 AVFETILLLPT-YVGVEVLKVSATDPDSEVPPELTYSLMEGSLDHFLIDSNSGVLTIKNN 1944
Query: 1590 LVPSQLIYNLIVSATDLGPERRKSTTELTIIL-QGLD-GPVFTQPKYITILKEGEPIGTN 1647
+ S+ Y LIV +D + ST+ +TI++ + +D G FTQ Y T + E T
Sbjct: 1945 NL-SKDHYMLIVKVSD---GKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITK 2000
Query: 1648 VISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAI-LDREQGACLYL 1706
V + A R +E P++Y I++ G F I +G+IQT + DRE+ L
Sbjct: 2001 VAIVNAVGNRLNE-PLKYSILN-------PGNKFKIKSTSGVIQTTGVPFDREEQELYEL 2052
Query: 1707 VDVYAIEKSTAFP--RTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTA 1764
V +E S R R V + ++DINDN PVF V+ + G+ I Q+TA
Sbjct: 2053 V----VEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTA 2108
Query: 1765 MDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRS-KYSLLVRADDGLQSS 1823
+D D+G N VTY ++ F I+P SG++I + + + +Y + + A DG + S
Sbjct: 2109 IDKDKGPNGEVTY-VLQDDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPS 2167
Query: 1824 -DMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE 1882
+ + ++ VN P F +P Y+ + ED + + +I AT + I YI+ +
Sbjct: 2168 LSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTPILSINATSPE---GQGIIYIIID 2224
Query: 1883 DDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDG-GGQFTTIRVYFNILDVNDNP 1941
D F ++ TGV + LDYEV Y LT+RA D G + V + DVNDNP
Sbjct: 2225 GDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDNP 2284
Query: 1942 PIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG--DSLGQFTVD-KNG 1998
PIF +Y+T+L E +G+ VL DAD N + Y I +S F +D +G
Sbjct: 2285 PIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSG 2344
Query: 1999 VLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL-T 2057
++ + LD E L V+ D P+ +S V I + DVNDNPP F +
Sbjct: 2345 LILTARMLDHELVQHCTLKVRSID-SGFPS--LSSEVLVHIYISDVNDNPPVFNQLIYES 2401
Query: 2058 YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGN---KFSIGTIDGEVRLTGELDR 2114
Y+ E P V QA+D DS +EY++L+ GN F + + G + L+ +
Sbjct: 2402 YVSELAPRGHFVTCVQASDADSSDFDRLEYSILS--GNDRTSFLMDSKSGVITLSNHRKQ 2459
Query: 2115 EEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDII 2174
Y+L V +D +S+ +V + VL N +P F+Q+ Y E+ EN GT +I
Sbjct: 2460 RMEPLYSLNVSVSD---GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVI 2516
Query: 2175 QVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREK--TPTYHLTVQAT 2232
V A DGD GT GQ+ Y I+N F IDS G + + LDRE + V+A
Sbjct: 2517 HVRATDGDPGTYGQISYAIINDFAKDRFLIDS-NGQVITTERLDRENPLEGDVSIFVRAL 2575
Query: 2233 DRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSN 2292
D G RT TV ++++D ND P F Y +V ++G + QV A D D G+N
Sbjct: 2576 DGGG--RTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGR-GHLVTQVQAIDPDDGAN 2632
Query: 2293 SKLSYVLFG-GNEDNAFTLSASGELG--VTQSLDRETKERFV-LMITATDSGSPALTGTG 2348
S+++Y L+ + A L + G VT+ + K + + A D G P
Sbjct: 2633 SRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLI 2692
Query: 2349 TINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQ- 2407
+ + V +P+F Y TI ED G+ V + S+N + G
Sbjct: 2693 PVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRIL---PSQNVWFSTVNGERPE 2749
Query: 2408 ------FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVND 2461
F I TG I LDRET + V + + + V + V D+ND
Sbjct: 2750 NNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLND 2809
Query: 2462 NPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNS-----EKFHID 2516
N P F+ Y T I G+ + V D D G N ++ YSL + E F+ID
Sbjct: 2810 NKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNID 2869
Query: 2517 PLRGAIMAAGPLNGASE--VTFSVHVKD-GGSFPKTDSTTVTVRFVNKADFPKVRAKE-- 2571
G I L+ ++ TFSV D G +F + + V+VR + D V A+E
Sbjct: 2870 SNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVY 2929
Query: 2572 ---QTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQID--QLTGQVSISQP 2626
P + V+ L T +S +SY+I GN F + Q +V + +P
Sbjct: 2930 RGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRP 2989
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRK 2686
LD E+ Y + I A DG F + ++++V DVNDN+P+ + + + + E++ K
Sbjct: 2990 LDREEQDIYFLNITATDG---LFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNK 3046
Query: 2687 -ILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKS 2745
IL VSA D D G NG + Y + G+ + F ++ +GE++++ LDRE++ Y L K+
Sbjct: 3047 IILKVSAKDADIGSNGYIRYSLY-GSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKA 3105
Query: 2746 SDKGSPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGIN 2804
+D G +++ +++ D NDN P F S ++ V EN+ +TRV D DIGIN
Sbjct: 3106 TDGGGRFCQSNIHLILE--DVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGIN 3163
Query: 2805 AISRYSIMD-ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDS--GWTVS--TDVT 2859
YS+ D A F+I+ S+G I++ +PL+RE Y I V A D G ++S T VT
Sbjct: 3164 RKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVT 3223
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEY-- 2917
I V DINDN P F R Y + PE T G++V VFAT D G+N ++ Y I+S +E
Sbjct: 3224 ITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGK 3283
Query: 2918 FRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSN 2977
F+IN TG I ++L Y+ R +V + D G P+L + TV IN+ D N
Sbjct: 3284 FKINPKTGGISVSEVLDYE--------LCKRFYLVVEAKDGGTPALSAVATVNINLTDVN 3335
Query: 2978 DNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDND 3037
DN P+F + Y ++++ VG +I + A +D D N ++ + I N + +F +D
Sbjct: 3336 DNPPKFSQDVYSAVISEDALVGDSVILLIA-EDVDSQPNGQIHFSIVNGDRDNEFTVDPV 3394
Query: 3038 TGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSAT 3097
G + V L + + + V A D G P +SS ATV+I +++ N ++P F+ ++ +A
Sbjct: 3395 LGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAV 3454
Query: 3098 IPESHSIGSIVRTVSARDRDAAMNG-LIKYSISSGNEEGIFAINSSTGILTLAKALDYEL 3156
I E+ +G+ + + DRD+ NG +SI SGNEE F ++ GIL A +
Sbjct: 3455 IQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPH-GILRSAVVFQHTE 3513
Query: 3157 CQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHL 3216
++ + + A D G + + + V VI+ + + P + + F +E+ G + +
Sbjct: 3514 SLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKI 3573
Query: 3217 NATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLD 3257
+ATD D V+ + ++S LF ++ + G I G LD
Sbjct: 3574 HATDQD--MYDVLTFALKSEQKSLFKVNSHDGKIIALGGLD 3612
Score = 1082 bits (2797), Expect = 0.0
Identities = 961/3308 (29%), Positives = 1541/3308 (46%), Gaps = 250/3308 (7%)
Query: 475 FSQQVYRVNLSEEAPPGSYVS-----GISATDGDSGLNANLRYSIVSGNGLGWFH----- 524
F+ +Y + E + +YV+ GI+ D L+ +++Y IVSG+ G+F
Sbjct: 43 FTHSIYNATVYENSAARTYVNSQSRMGITLID----LSWDIKYRIVSGDEEGFFKAEEVI 98
Query: 525 ISEHSGL---VTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPV 581
I++ L G+S L+RE+ +L + +G ++ ++ + +LD+ND +P+
Sbjct: 99 IADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRG-EDLEAWTKVNIQVLDMNDLRPL 157
Query: 582 FSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRL 641
FS P Y V++ E+ P T + + ATD D+G NG + + F + P SG +
Sbjct: 158 FS-PTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVD---LFSVHPTSGVI 213
Query: 642 STISSLDREEQAFYSLLVLATD-----LGSPPQSSMARINVSLLDINDNSPVFYPVQYFA 696
S L+ +E+ Y L +LA D G+ SS A++ V + IN+++P + V +
Sbjct: 214 SLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVP 273
Query: 697 HIKENEPGGSYITTVSATDPDLGTNGTVK-YSISAGDRSRFQVNAQSG------VISTRM 749
E EP + +T D D G NG ++ SI AGD A+ G I R
Sbjct: 274 FSLEKEPTYAVVT---VDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERK 330
Query: 750 ALDREE-KTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPV-FSQVAYSFVVFENVA 807
+D E Y L + A D G+ Q + T+D P+ F + Y + E
Sbjct: 331 QIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSP 390
Query: 808 LGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVV 867
G V V S + ++ Y ++ G+ F IN +G + TA ++ ++ Y+L+V
Sbjct: 391 PGVVVAIVKLSPEPI--DVEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVT 448
Query: 868 ASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGM 927
G + V I+++D ND++P F Q + V E+ G S+ A D D+G NG
Sbjct: 449 NKEGDL--KAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGY 506
Query: 928 VLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGS--YQIEILASDMGVP-QLSSSVILTV 984
+ YS+ F IN+ G IS LD + Y+ + ASD G P + S V +T+
Sbjct: 507 ITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTI 566
Query: 985 YVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAF 1044
+ +VNDNSP+F++++ + +S PV V A D D + Y I GN F
Sbjct: 567 RIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDE--LELVKYKIISGNELGFF 624
Query: 1045 GIFPD-GQLYIKSELDRE--LQDRYVLMVVASD--RAVEPLSATVNV------------- 1086
+ PD G L +K L + L + A+D +P+S ++V
Sbjct: 625 YLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKSFSCR 684
Query: 1087 --------------------TVILED-------VNDNRPLFN-STNYTFYFEEEQRAGSF 1118
+ LED +N P F+ S +E+ G+
Sbjct: 685 ETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGAN 744
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNTHQFDRESLMRRRGTAVFS 1176
+ K+ A D D G NG+V ++ D F + +G++ DRE T ++
Sbjct: 745 ILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREH------TDLYL 798
Query: 1177 FTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASD 1236
+ D G PQ + + ++D NDN+P F++D Y I ES+ T++++V A D
Sbjct: 799 LNITIYDLGNPQK-SSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARD 857
Query: 1237 VDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTI--P 1294
D G+NG + YS++ + +QFAI+S++G V + +LD E+ YSL I+A D
Sbjct: 858 KDLGSNGEVTYSVL--TDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQ 915
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
L S TL + + D ND +P+F S+ V VLE++ +G +++ + D D G + YS+
Sbjct: 916 LFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSL 975
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVV-IHVRDF 1413
N G F I +G+I L+K+LD+E Q Y L + AKD+GRP S++S V + V D
Sbjct: 976 VNDYN-GRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDV 1034
Query: 1414 NDN--PPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
N+N P FP + S+ EN IGTSV+ VTA D D+ +G++ Y+I G F+I
Sbjct: 1035 NENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLG-RFSI 1093
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
D+ G I +DRE + LTV A D+ V Y+ V I V D+NDN P+
Sbjct: 1094 DDESGVITAADILDRETMGSYWLTVYATDRGV---VPLYSTIEVYIEVEDVNDNAPLTSE 1150
Query: 1532 --QNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDTFI-VDRYSGDLRVAS 1588
+ + S SV+ I A DPD +N ++ Y I +G+ F ++ +G + S
Sbjct: 1151 PIYYPVVMENSPKDVSVI-QIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTS 1209
Query: 1589 ALV--PSQLIYNLIVSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYITIL---- 1638
+ Q + L V+ TD GP ++ST + +++Q LD P F + Y L
Sbjct: 1210 RKLDREQQAEHFLEVTVTDGGPSPKQST--IWVVVQVLDENDNKPQFPEKVYQIKLPERD 1267
Query: 1639 --KEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAIL 1696
K GEPI + G A + Y IV + K F I TG++ +
Sbjct: 1268 RKKRGEPI---YRAFAFDRDEGPNAEISYSIVDGNDDGK-----FFIDPKTGMVSSR--- 1316
Query: 1697 DREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEE----- 1751
++ A Y D+ I K+ R Q++ + PP P + LT +E
Sbjct: 1317 -KQFTAGSY--DILTI-KAVDNGRPQKSSTARLHIEWIKKPPPSP---IPLTFDEPFYNF 1369
Query: 1752 NIGDGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKY 1810
+ + ++ ++ + + + AN + + I+ G D +F + G ++ + LD E+RS Y
Sbjct: 1370 TVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIY 1429
Query: 1811 SLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDS 1870
++ V DG + ++ I V D ND+ P+FS+P Y I ED +P + + I ATD D
Sbjct: 1430 NMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDE 1489
Query: 1871 GVNGEITYIVNEDDED---GIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQF-- 1925
+++Y V+ + F ++P TGV LD+E Q +IL + D +
Sbjct: 1490 --KHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRR 1547
Query: 1926 TTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIAS 1985
RV N+ D ND+ P F+ Y S+ E+ +GS VL D D G N++L Y+I +
Sbjct: 1548 NLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEA 1607
Query: 1986 GDSLGQFTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDV 2044
G++ F ++ G++ + K D + + L ++V D P S T+ ++S+ + D
Sbjct: 1608 GNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSA-TAIVRISVTMSD- 1665
Query: 2045 NDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDG 2104
N +P + EN I T V A ++ I + F+I G
Sbjct: 1666 NSHPKFIHKDYQAEVNENVDIGTSVILISAI----SQSTLIYEVKDGDINGIFTINPYSG 1721
Query: 2105 EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEIN 2164
+ LD E S+Y L + AT+ ++S+ V + ++D NDN P+F + Y ++
Sbjct: 1722 VITTQKALDYERTSSYQLIIQATN--MAGMASNATVNIQIVDENDNAPVFLFSQYSGSLS 1779
Query: 2165 E--------NTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKP 2216
E +L + ++ + A D D N + Y IV + F +DS TGAI
Sbjct: 1780 EAAPINSIVRSLDNSPLV-IRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIAN 1838
Query: 2217 LDREKTPTYHLTVQATDRGSTPRTDTS--TVSIVLLDINDFVPVFELSPYS--VNVPENL 2272
LD E +H V D GS T S V+I + D+ND PVF + + + +P +
Sbjct: 1839 LDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYV 1898
Query: 2273 GTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVL 2332
G +L+V A D D +L+Y L G+ D+ S SG L + + +K+ ++L
Sbjct: 1899 GV---EVLKVSATDPDSEVPPELTYSLMEGSLDHFLIDSNSGVLTIKN--NNLSKDHYML 1953
Query: 2333 MITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDAD 2392
++ +D T + ++V + D+ F Y T+I E+ T V +VNA
Sbjct: 1954 IVKVSDG---KFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNR 2010
Query: 2393 ASKNAVIRIIGGNSQFTINPSTGQIITSAL-LDRETKDNYTLVVVCSDAGSPEPLSSSTS 2451
++ I+ ++F I ++G I T+ + DRE ++ Y LVV S +
Sbjct: 2011 LNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEAS-RELDHLRVARVV 2069
Query: 2452 VLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSE 2511
V V + D+NDN P F PY + PG+ ++ VT D D GPN E+ Y L +
Sbjct: 2070 VRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQD-DYG 2128
Query: 2512 KFHIDPLRGAIMAAGPLNG-ASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKADFPKVR 2568
F I+P G ++ N S + + V + KDGG + S + + VNKA P
Sbjct: 2129 HFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKA-MPVFD 2187
Query: 2569 AKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLD 2628
T E+ +++ + +I +S G+ + Y I G+ F ID TG + + PLD
Sbjct: 2188 KPFYTASVNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLD 2247
Query: 2629 FEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILE-NLSPRKI 2687
+E Y + I A D + +D+ V DVNDN PIF + + + + E +L +
Sbjct: 2248 YEVTSAYKLTIRASD-ALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPV 2306
Query: 2688 LTVSAMDKDSGPNGQLDYEIVNG--NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKS 2745
L V ++D DS N + Y+IV N + F I+ ++G I + R LD E V H L ++S
Sbjct: 2307 LQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRS 2366
Query: 2746 SDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGIN 2804
D G PS S+ V V I I D NDN P F+Q I+ ++V E +P G+ VT V SD D
Sbjct: 2367 IDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDF 2426
Query: 2805 AISRYSIMDAS--LPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFV 2862
YSI+ + F ++ +G I +S + Y + VS D +T + V I V
Sbjct: 2427 DRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRV 2486
Query: 2863 TDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQ--SEYFRI 2920
N +P FS+++Y + E G+KV V ATD D G+ GQ+ Y I + + F I
Sbjct: 2487 LGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLI 2546
Query: 2921 NATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
+ + G++ + L +N +V+I F+ G+ + TV + +VD NDNA
Sbjct: 2547 D-SNGQVITTERLDRENPLE-GDVSI----FVRALDGGGRTTF---CTVRVIVVDENDNA 2597
Query: 2981 PQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLG---KFKLDND 3037
PQF+ +Y V +V G + +V AID D G NS + Y + ++ + ++D D
Sbjct: 2598 PQFMTVEYRASVRADVGRGHLVTQVQAIDPDD-GANSRITYSLYSEASVSVADLLEIDPD 2656
Query: 3038 TGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSAT 3097
GW+ + N V A D G P S V+I V P F+QS S T
Sbjct: 2657 NGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFT 2716
Query: 3098 IPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELC 3157
I E +IGS V T+ + N+ GIF I TG + L K LD E
Sbjct: 2717 IAEDTAIGSTVDTLRILPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETS 2776
Query: 3158 QKHEMTISA-IDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHL 3216
++A I V V + V+D+NDN PVF + Y ++E P GT + +
Sbjct: 2777 PAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQV 2836
Query: 3217 NATDADSGTNAVIAYTVQSSDS-----DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAF 3271
A D D G N + Y++ S + F ID NTG I+T LD ET ++ +V A
Sbjct: 2837 RAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVAS 2896
Query: 3272 NVPDE-ERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG-T 3329
++ + S A V++++ N+ P F ++Y + E+ P G +V + DRD
Sbjct: 2897 DLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDV 2956
Query: 3330 DGEVHYLIFGNSRKKGFQIN--KKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADID 3387
+ +V Y I G + + F + + ++YV LDRE+++ L + A + G +
Sbjct: 2957 NRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATD-----GLFVT 3011
Query: 3388 EVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSD-SIPSWSRFSYFIG 3445
+ V V+V D ND P+ Y+ + E +P + VSA D+D + R+S + G
Sbjct: 3012 QAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLY-G 3070
Query: 3446 SGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDIND 3505
SGN F ++P++G++ A LDRE +P+Y+L A D G + L+ LED+ND
Sbjct: 3071 SGNSE--FFLDPESGELKTLALLDRERIPVYSLMAKATDGGGRFCQSNIHLI--LEDVND 3126
Query: 3506 NGPMLTVSEGE--VMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTA 3563
N P+ + V EN L+ +Q+ DPD+ N+ Y L+ + S++
Sbjct: 3127 NPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRK--VVYSLADSAGGVFSIDSSS 3184
Query: 3564 GVLSTTREIDREQIADFYLSVVTKDSGVPQ-MSSTGTVHITVIDQNDNPSQSRTVEIFVN 3622
G++ + +DREQ + + +SV D Q +SS TV ITV+D NDNP + V
Sbjct: 3185 GIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVT 3244
Query: 3623 YYGNLFPG 3630
+ PG
Sbjct: 3245 VPEDTSPG 3252
Score = 1063 bits (2750), Expect = 0.0
Identities = 1012/3577 (28%), Positives = 1614/3577 (45%), Gaps = 296/3577 (8%)
Query: 119 TEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIR 178
T+V + V D+ND P+F + VT E + V TATD+DIGSNG + ++
Sbjct: 142 TKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFK--- 198
Query: 179 GNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNV 238
N+ F + T SG + G L+ + +Y L + D+G K G V+
Sbjct: 199 -NKVDLFSVHPT---SGV-----ISLSGRLNYDEKNRYDLEILAVDRG-MKLYGNNGVSS 248
Query: 239 T------VQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDE 292
T ++ IN++ P H VP + V D D+G N +I
Sbjct: 249 TAKLYVHIERINEHAPTI---HVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIESVSIVA 305
Query: 293 GTP---FQMDPE-----TGLITVREPLDFEA-RRQYSLTVQAMDRGVPSLTGRAEALIQL 343
G P F + E I R+ +D+E+ Y+LT+QA D+G P +A+
Sbjct: 306 GDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIG 365
Query: 344 LDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNE 403
D P+ F S+ E + G VVA++ ++ ++ ++ G +
Sbjct: 366 NPTRDTVPI----RFEKEVYDVSISEFSPPGVVVAIVKLSPEPI-----DVEYKLSPGED 416
Query: 404 QRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVI 463
+F++ P LI A L+ + Y L V+ + A + I
Sbjct: 417 AVYFKIN----PRSGLIVTARPLNTVKKEVYKLEVTNKEG------------DLKAQVTI 460
Query: 464 FVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWF 523
+ D NDH P F Q +Y ++E P G+ V +SA+D D G N + YSI S N L F
Sbjct: 461 SIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLP-F 519
Query: 524 HISEHSGLVTTGSSGGLDRELASQIV-LNISARDQG-VHPKVSYAQLVVTLLDVNDEKPV 581
I++ +G+++T LD E + +I + A D G + S + + + +VND P+
Sbjct: 520 VINQFTGVISTTEE--LDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPL 577
Query: 582 FSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRL 641
F + V + + P G + + A D D + V++ + + F L+P SG L
Sbjct: 578 FEKVACQGV-ISYDFPVGGHITAVSAIDID--ELELVKYKIISG-NELGFFYLNPDSGVL 633
Query: 642 STISSLDRE--EQAFYSLLVLATDLGSPPQSSMARINVSL-------------------- 679
SL + ++L + ATD G M+ IN+S+
Sbjct: 634 QLKKSLTNSGIKNGNFALRITATD-GENLADPMS-INISVLHGKVSSKSFSCRETRVAQK 691
Query: 680 --------------LDINDNSPVFYPVQ----YF-------AHIKENEPGGSYITTVSAT 714
L++ D FY + YF +KE+ P G+ I + A
Sbjct: 692 LAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAY 751
Query: 715 DPDLGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQS 773
D D G NG V ++IS G+ S F ++ ++G + M +DRE Y L I D GN Q
Sbjct: 752 DADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQK 811
Query: 774 PNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLIT 831
+ ++TI V D DN PVF Q +YS + E+ +G + V A DL SN ++Y +
Sbjct: 812 SSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVL 871
Query: 832 TGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNIT-----VKDL 886
T Q+ FAIN TG + A+ +DRE ++ Y LK+ A +G + ++ + D+
Sbjct: 872 TDTQQ--FAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDV 929
Query: 887 NDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKN 946
ND SP F+ + SV V+E+ G I + DPD G+ G V YSL + F I++ +
Sbjct: 930 NDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKAS 989
Query: 947 GTISLLGPLDVHAGS-YQIEILASDMGVP-QLSSSVILTVYVHDVNDN--SPVFDQLSYE 1002
G I L LD Y + + A D G P LSS + V V DVN+N +P F +
Sbjct: 990 GAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVV 1049
Query: 1003 VTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRE 1061
++ E+ + + +V A D+DSG +GEI Y+I +G+ F I + G + LDRE
Sbjct: 1050 GSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRE 1109
Query: 1062 LQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGK 1121
Y L V A+DR V PL +T+ V + +EDVNDN PL + Y E V +
Sbjct: 1110 TMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQ 1169
Query: 1122 VSAVDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNT-HQFDRESLMRRRGTAVFSFT 1178
+ A D D N ++ Y P F ++ +G IT T + DRE F
Sbjct: 1170 IQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEH-------FL 1222
Query: 1179 VIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANL--TQVLRVSASD 1236
+ G P P + V V + D NDN P+F + YQ + E + R A D
Sbjct: 1223 EVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFD 1282
Query: 1237 VDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN 1296
DEG N I YSI+ GN++ +F ID +G V+ + + A L I+AVD+G +
Sbjct: 1283 RDEGPNAEISYSIVDGNDDGKFFIDPKTGMVS--SRKQFTAGSYDILTIKAVDNGRPQKS 1340
Query: 1297 STCTLNIDILDENDNTP---SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYS 1353
ST L+I+ + + +P +F + V+E+ R+ E+V V+ + N L++
Sbjct: 1341 STARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPA----NTPLWFD 1396
Query: 1354 ITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDF 1413
I G N F G+I +AK LD E +S+Y +++ D + V I V D
Sbjct: 1397 IVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTD---GTNVAVTQVFIKVLDN 1453
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMP--RGNHFTI 1471
NDN P F + +I E++ T ++ + A D D +LSYT+ + F I
Sbjct: 1454 NDNGPEFSQPNYDVTISEDVLPDTEILQIEA--TDRDEKHKLSYTVHSSIDSISMRKFRI 1511
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
D G +YT +D E + L + DQ P R L V + V D ND+ P F +
Sbjct: 1512 DPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPY---RRNLARVIVNVEDANDHSPYFTN 1568
Query: 1532 Q-NALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVA-- 1587
+ SA +GS + + A D D+G N E+ Y I G+T + F ++ G + +
Sbjct: 1569 PLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKE 1628
Query: 1588 -SALVPSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGT 1646
Q + ++ V+ P + +++ + P F Y + E IGT
Sbjct: 1629 PDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGT 1688
Query: 1647 NVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYL 1706
+VI I A S++ + Y + ++ + +FTI ++G+I T LD E+ + L
Sbjct: 1689 SVILISAI----SQSTLIYEV-----KDGDINGIFTINPYSGVITTQKALDYERTSSYQL 1739
Query: 1707 VDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQL---- 1762
+ I+ + A V I + D NDN PVF ++ E S + L
Sbjct: 1740 I----IQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSP 1795
Query: 1763 ---TAMDADEGANALVTYTII-SGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADD 1818
A DAD NAL+ Y I+ S A F +D +G + LD E + + V D
Sbjct: 1796 LVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRD 1855
Query: 1819 G-----LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVN 1873
S + +NI V+DVND+ P F++ V+ + T G V + ATD DS V
Sbjct: 1856 SGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVP 1915
Query: 1874 GEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFN 1933
E+TY + E D F ++ +GV LT + + +Y+L V+ D G ++T V
Sbjct: 1916 PELTYSLMEGSLDH-FLIDSNSGV--LTIKNNNLSKDHYMLIVKVSD-GKFYSTSMVTIM 1971
Query: 1934 ILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFT 1993
+ + D+ F+ + YSTS+ EN + V + N + +N L YSI + + +
Sbjct: 1972 VKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNA--VGNRLNEPLKYSILNPGNKFKIK 2029
Query: 1994 VDKNGVLKVLKALDRESQSFYNLVVQV-HDLPQIPASRFTSTAQVSIILLDVNDNPPTFL 2052
+ DRE Q Y LVV+ +L + +R V + + D+NDN P F+
Sbjct: 2030 STSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVV----VRVNIEDINDNSPVFV 2085
Query: 2053 S-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGE 2111
P + + T++++ A D D GPN + Y L + G+ F I G V L E
Sbjct: 2086 GLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGH-FEINPNSGNVILK-E 2143
Query: 2112 LDREEVSN--YTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLT 2169
++SN Y +T++A D G+PSLS+S E+ + + +N P+F + Y +NE+
Sbjct: 2144 AFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITI--VNKAMPVFDKPFYTASVNEDIRM 2201
Query: 2170 GTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTV 2229
T I+ + A EG + Y I++G+ ++F ID TG + V PLD E T Y LT+
Sbjct: 2202 NTPILSI-NATSPEGQG--IIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTI 2258
Query: 2230 QATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDR 2289
+A+D + R + TV +++ D+ND P+F+ Y+ + E + +LQVV+ D D
Sbjct: 2259 RASDALTGARAEV-TVDLLVNDVNDNPPIFDQPTYNTTLSE-ASLIGTPVLQVVSIDADS 2316
Query: 2290 GSNSKLSYVLFGG--NEDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGSPALTG 2346
+N + Y + N + F + S+SG + + LD E + L + + DSG P+L+
Sbjct: 2317 ENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSS 2376
Query: 2347 TGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADAS--KNAVIRIIGG 2404
+++ + DVNDN P F Y + + E AP G V V ASDAD+S I+ G
Sbjct: 2377 EVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSG 2436
Query: 2405 N--SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
N + F ++ +G I S + + Y+L V SD +S+ V + V N
Sbjct: 2437 NDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDG----LFTSTAQVHIRVLGANLY 2492
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRNSEKFHIDPLRGA 2521
P F YV + G+ V V TD D G ++ Y+ ++ ++F ID G
Sbjct: 2493 SPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDS-NGQ 2551
Query: 2522 IMAA------GPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTF 2574
++ PL G +V+ V DGG +T TV V V++ D P+ E
Sbjct: 2552 VITTERLDRENPLEG--DVSIFVRALDGGG--RTTFCTVRVIVVDENDNAPQFMTVEYRA 2607
Query: 2575 MFPENQPVSSLVTTI------TGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLD 2628
+ LVT + G++ R Y AS ++ + +ID G + +
Sbjct: 2608 SVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFN 2667
Query: 2629 FEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKIL 2688
K +++A DGG P S + I VL P F + + I E+ + +
Sbjct: 2668 QLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTV 2727
Query: 2689 TVSAMDKDSGPNGQLDYEIVNG-----NMENSFSINHATGEIRSVRPLDREKVSHYVLTI 2743
+ P+ + + VNG N F I TG I+ + LDRE + +
Sbjct: 2728 DTLRI----LPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKV 2783
Query: 2744 KSS-DKGSPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDI 2801
++ +V V I +LD NDN P F + + + E P+G +T+V D D
Sbjct: 2784 AATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDW 2843
Query: 2802 GINAISRYSIMDASLP------FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVS 2855
G N YS+ S P F I+ +TG I + L+ E + V A D G S
Sbjct: 2844 GANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFS 2903
Query: 2856 TD----VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGS-NGQVFYF 2910
V++ VTDINDNAP F++ Y + E G V + D D N QV Y
Sbjct: 2904 LSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYH 2963
Query: 2911 IKSQSEYFR----INATTGEIFNKQIL-KYQNVTGFSNVNINRHSFIVTSSDRGKPSLIS 2965
I + R + + +++ K+ L + + F N+ F ++
Sbjct: 2964 ITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLF------------VT 3011
Query: 2966 ETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN 3025
+ V +++ D NDN+P + Y + +++ +++V+A D D G N + Y +
Sbjct: 3012 QAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSA-KDADIGSNGYIRYSLYG 3070
Query: 3026 DNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 3085
+ +F LD ++G + + L + + + A D G Q+ +H+ + + N +
Sbjct: 3071 SGN-SEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGG--RFCQSNIHLILEDVNDN 3127
Query: 3086 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGI 3145
P FS H + + E+ + +++ V A D D +N + YS++ + G+F+I+SS+GI
Sbjct: 3128 PPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLAD-SAGGVFSIDSSSGI 3186
Query: 3146 LTLAKALDYELCQKHEMTISAID-GGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
+ L + LD E + +++ A D + + +VT+ V+D+NDN PVF DY TV
Sbjct: 3187 IILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVP 3246
Query: 3205 ENAPSGTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQGFLDFETKQS 3263
E+ GT V+ + AT D GTNA I Y ++S ++ F I+P TG I+ LD+E +
Sbjct: 3247 EDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKR 3306
Query: 3264 YHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFAS 3323
++L V+A + + ATVNI L N+ P+F +Y ISE A G V + A
Sbjct: 3307 FYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAE 3366
Query: 3324 DRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRG 3383
D D +G++H+ I R F ++ G + V LDRE+ SL V A + G
Sbjct: 3367 DVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGI--P 3424
Query: 3384 ADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY 3442
A TVN+ + D ND P+FT Y+ I E P+GT + + D DS + FS+
Sbjct: 3425 AMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSF 3484
Query: 3443 FIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLED 3502
I SGNE F ++P + E+L Y L V A DSG P + V + +
Sbjct: 3485 SILSGNEEEEFVLDPHGILRSAVVFQHTESLE-YVLCVQAKDSGKPQQVSHTYIRVRVIE 3543
Query: 3503 INDNGPMLTVSEGEV--MENKRPGTLVMTLQSTDPDL 3537
+ + P E + ME+ PG ++ + +TD D+
Sbjct: 3544 ESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDM 3580
Score = 922 bits (2384), Expect = 0.0
Identities = 840/2796 (30%), Positives = 1286/2796 (45%), Gaps = 213/2796 (7%)
Query: 50 QVLEEQPPGTLVGTIQTRP-----GFTYRLS---ESHALFAINSSTGALYTTSTIDRESL 101
+VLE+ P GT++ ++T G R S + + F I+ ++GA+ + +D E
Sbjct: 944 KVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEK- 1002
Query: 102 PSDVINLVVLSSAPTYPTE------VRVLVRDLNDN--APVFPDPSIVVTFKEDSSSGRQ 153
NL V + P V V V D+N+N P FPD ++V + KE+S G
Sbjct: 1003 -QQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTS 1061
Query: 154 VILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVT 213
V+ TA D D G +G Y I G+ GRF +D + SG + + LDRE
Sbjct: 1062 VLQVTARDEDSGRDG--EIQYSIRDGSGLGRFSID---DESGV-----ITAADILDRETM 1111
Query: 214 PQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVA 273
Y L V D+G ++V + V+D+NDN P+ Y V E++ SV+Q+
Sbjct: 1112 GSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQ 1171
Query: 274 AADADEGTNADIRYRLQDEGTP---FQMDPETGLI-TVREPLDFEARRQYSLTVQAMDRG 329
A D D +N + YR+ G P F ++ +TGLI T LD E + ++ L V D G
Sbjct: 1172 AEDPDSSSNEKLTYRI-TSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGG 1230
Query: 330 VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDE--NAQVGTVVALLTVTDADS 387
++Q+LD NDN P FP + E + G + D D
Sbjct: 1231 PSPKQSTIWVVVQVLDENDNKP-----QFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDE 1285
Query: 388 PAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYN-LTVSVSDNYGA 446
N IS I+ GN+ F + P ++ S+ + SY+ LT+ DN G
Sbjct: 1286 -GPNAEISYSIVDGNDDGKFFID----PKTGMV---SSRKQFTAGSYDILTIKAVDN-GR 1336
Query: 447 PPGAAVQARSSVASLVIFVNDINDHPP-----VFSQQVYRVNLSEEAPPGSYVSGISATD 501
P +SS A L + I PP F + Y + E V +S
Sbjct: 1337 P------QKSSTARL--HIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQP 1388
Query: 502 GDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHP 561
N L + IV GN F + G + LD E S +++ D
Sbjct: 1389 A----NTPLWFDIVGGNFDSAFDAEKGVGTIVIAKP--LDAEQRSIYNMSVEVTD---GT 1439
Query: 562 KVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFS 621
V+ Q+ + +LD ND P FSQP YDV++ E+ TE+L + ATD D +
Sbjct: 1440 NVAVTQVFIKVLDNNDNGPEFSQP-NYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVH 1498
Query: 622 LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
R FR+DP +G L T LD E Q + L ++ D P + ++AR+ V++ D
Sbjct: 1499 SSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVED 1558
Query: 682 INDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR-SRFQVNA 740
ND+SP F Y A + E+ GS + V+A D D G N + Y+I AG+ + F++
Sbjct: 1559 ANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEP 1618
Query: 741 QSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSF 800
G+I+ D + L I TD G+ AIV I+V + ++ P F Y
Sbjct: 1619 VLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQA 1678
Query: 801 VVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQS 860
V ENV +G V +SA + S + Y + GD G+F IN +G +TT +D E S
Sbjct: 1679 EVNENVDIGTSVILISAIS---QSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTS 1735
Query: 861 FYQLKVVASG-GTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVEN-------WQAGHSI 912
YQL + A+ + + VNI + D NDN+P FL + S ++ E +S
Sbjct: 1736 SYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSP 1795
Query: 913 FQAKAVDPDEGVNGMVLYSL-KQNPKNLFAINEKNGTISLLGPLDVHA-GSYQIEILASD 970
+A D D N +++Y + + K F ++ G I + LD + + D
Sbjct: 1796 LVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRD 1855
Query: 971 MGVPQLS--SSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGAN 1028
G PQL+ S V + + V DVNDN PVF Q +E L V KV A+D DS
Sbjct: 1856 SGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVP 1915
Query: 1029 GEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTV 1088
E+ Y++ EG+ G L IK+ + +D Y+L+V SD +T VT+
Sbjct: 1916 PELTYSLMEGSLDHFLIDSNSGVLTIKN--NNLSKDHYMLIVKVSD---GKFYSTSMVTI 1970
Query: 1089 ILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFEL 1148
++++ D+ F + Y+ E + V V+AV N ++YS F++
Sbjct: 1971 MVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRL--NEPLKYSILNPGNKFKI 2028
Query: 1149 HAISGEITNTH-QFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNA 1207
+ SG I T FDRE ++ V A+ + + + V V ++DINDN+
Sbjct: 2029 KSTSGVIQTTGVPFDREE------QELYELVVEASRE-LDHLRVARVVVRVNIEDINDNS 2081
Query: 1208 PKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQV 1267
P F+ Y A + A T + +V+A D D+G NG + Y + ++ F I+ SG V
Sbjct: 2082 PVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTY--VLQDDYGHFEINPNSGNV 2139
Query: 1268 TLIGKLDYE-ATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLE 1326
L + + + Y + I A D G L+++ L I I+ N P F K V E
Sbjct: 2140 ILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIV--NKAMPVFDKPFYTASVNE 2197
Query: 1327 NMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLY 1386
++R+ + S+ AT S + + Y I + F+I +TG + + LD+E S Y
Sbjct: 2198 DIRMNTPILSINAT---SPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAY 2254
Query: 1387 KLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHD 1446
KL I A D R+ ++V + V D NDNPP F ++ E IGT V+ V + D
Sbjct: 2255 KLTIRASDALTGARAE-VTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSID 2313
Query: 1447 PDADINGQLSYTIIQQMPRG-NHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPI 1505
D++ N + Y I+Q ++F ID G I T +D E L V++ D P
Sbjct: 2314 ADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPS 2373
Query: 1506 ETRRYALKNVTILVTDLNDNVPMFISQNALA----ADPSAVIGSVLTTIMAADPDEGANG 1561
+ V I ++D+NDN P+F N L A G +T + A+D D
Sbjct: 2374 LSSEVL---VHIYISDVNDNPPVF---NQLIYESYVSELAPRGHFVTCVQASDADSSDFD 2427
Query: 1562 EIEYEIING-DTDTFIVDRYSGDLRVAS-ALVPSQLIYNLIVSATDLGPERRKSTTELTI 1619
+EY I++G D +F++D SG + +++ + +Y+L VS +D G + + +
Sbjct: 2428 RLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSD-GLFTSTAQVHIRV 2486
Query: 1620 ILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVG 1678
+ L P F+Q Y+ ++E GT VI + A G+ + Y I++ +++
Sbjct: 2487 LGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDR--- 2543
Query: 1679 RLFTIGRHTGIIQTAAILDRE---QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDIND 1735
F I + +I T LDRE +G V ++ + RT V + + D ND
Sbjct: 2544 --FLIDSNGQVITTER-LDRENPLEGD----VSIF-VRALDGGGRTTFCTVRVIVVDEND 2595
Query: 1736 NPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGAD----DSFRIDP 1791
N P F T +V ++G G + Q+ A+D D+GAN+ +TY++ S A D IDP
Sbjct: 2596 NAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDP 2655
Query: 1792 ESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSF 1848
++G ++ ++ + + S V+A DG ++ S + + I V P F++ YSF
Sbjct: 2656 DNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSF 2715
Query: 1849 DIPEDTIPGSLVAAILATDDD----SGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLL 1904
I EDT GS V + S VNGE E+++ GIF + TG L + L
Sbjct: 2716 TIAEDTAIGSTVDTLRILPSQNVWFSTVNGERP----ENNKGGIFVIEQETGTIKLDKRL 2771
Query: 1905 DYEVQQYYILTVRAE---DGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGS 1961
D E + V A D T+ V +LD+NDN P+F +SY T +ME +PVG+
Sbjct: 2772 DRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGT 2831
Query: 1962 TVLVFNVTDADDGINSQLTYSIASGDS----LGQFTVDKN-GVLKVLKALDRESQSFYNL 2016
+ D D G N Q+TYS+ S + F +D N G + LK LD E+ +
Sbjct: 2832 KLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTF 2891
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT-YIPENTPIDTVVFKAQAT 2075
V DL + A +STA VS+ + D+NDN P F + E+ P VV
Sbjct: 2892 SVVASDLGE--AFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTW 2949
Query: 2076 DPD-SGPNSYIEYTLL--NPLGNKFSIGTIDGE--VRLTGELDREEVSNYTLTVVATDKG 2130
D D S N + Y + NP G +F++G + E V + LDREE Y L + ATD
Sbjct: 2950 DRDTSDVNRQVSYHITGGNPRG-RFALGLVQSEWKVYVKRPLDREEQDIYFLNITATD-- 3006
Query: 2131 QPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVR 2190
+ V V V D+NDN+P+ Q Y + E+ + I++V A D D G+NG +R
Sbjct: 3007 -GLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIR 3065
Query: 2191 YGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLL 2250
Y + G+ N EF +D +G + LDRE+ P Y L +ATD G R S + ++L
Sbjct: 3066 YSLY-GSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGG--RFCQSNIHLILE 3122
Query: 2251 DINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL 2310
D+ND PVF Y+ V EN T + +V A D D G N K+ Y L + F++
Sbjct: 3123 DVNDNPPVFSSDHYNTCVYENTAT-KALLTRVQAVDPDIGINRKVVYSL-ADSAGGVFSI 3180
Query: 2311 -SASGELGVTQSLDRETKERFVLMITATD-SGSPALTGTGTINVIVDDVNDNVPTFASKA 2368
S+SG + + Q LDRE + + + + ATD S +L+ T+ + V D+NDN P F +
Sbjct: 3181 DSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRD 3240
Query: 2369 YFTTIPEDAPTGTDVLLVNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLD 2424
Y T+PED GT VL V A+ D NA I I GN Q F INP TG I S +LD
Sbjct: 3241 YLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLD 3300
Query: 2425 RETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSF 2484
E + LVV D G+P LS+ +V + +TDVNDNPP+F Y I L G
Sbjct: 3301 YELCKRFYLVVEAKDGGTP-ALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDS 3359
Query: 2485 VFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLRGAIMAAGPLN--GASEVTFSVHVK 2541
V + D D PN ++H+S+ +G +F +DP+ G + L+ S + V
Sbjct: 3360 VILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAV 3419
Query: 2542 DGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSS----LVTTITGSSLRG 2596
D G + + TV + + D P T + EN+PV + LV T S G
Sbjct: 3420 DSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNG 3479
Query: 2597 EPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLD 2656
P S+ I SGN F +D G + + + +YV+ ++A+D G P S+ +
Sbjct: 3480 PPFSFSILSGNEEEEFVLDP-HGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIR 3538
Query: 2657 ITVLDVNDNAP-IFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYEI----VNGN 2711
+ V++ + + P + FI + ++ I + A D+D Y++ +
Sbjct: 3539 VRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDM-------YDVLTFALKSE 3591
Query: 2712 MENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSD 2747
++ F +N G+I ++ LD K YVL + SD
Sbjct: 3592 QKSLFKVNSHDGKIIALGGLDSGK---YVLNVSVSD 3624
Score = 894 bits (2310), Expect = 0.0
Identities = 766/2601 (29%), Positives = 1198/2601 (46%), Gaps = 177/2601 (6%)
Query: 43 AEPRQVFQVLEEQPPGTLVGTIQ-------TRPGFTYRLSESHA--LFAINSSTGALYTT 93
+EP V+E P V IQ + TYR++ + FAIN TG + TT
Sbjct: 1149 SEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTT 1208
Query: 94 ST-IDRESLPSDVINLVVLSSAPTYPTE---VRVLVRDLNDNAPVFPDP--SIVVTFKED 147
S +DRE + + V P+ V V V D NDN P FP+ I + ++
Sbjct: 1209 SRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDR 1268
Query: 148 SSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGG 207
G + A D D G N SY I+ GN+ G+F +D +G + + G
Sbjct: 1269 KKRGEPIYRAFAFDRDEGPNA--EISYSIVDGNDDGKFFID---PKTGMVSSRKQFTAGS 1323
Query: 208 LDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPP-----VFGSSHYQAGVPED 262
D L ++ D G P++ ++++ + I PP F Y V E
Sbjct: 1324 YDI-------LTIKAVDNGRPQKSSTARLHI--EWIKKPPPSPIPLTFDEPFYNFTVMES 1374
Query: 263 AVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLT 322
V V V+ A+ DI D F + G I + +PLD E R Y+++
Sbjct: 1375 DRVTEIVGVVSVQPANTPLWFDIVGGNFDSA--FDAEKGVGTIVIAKPLDAEQRSIYNMS 1432
Query: 323 VQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
V+ D ++T + I++LD NDN P F + ++ E+ T + +
Sbjct: 1433 VEVTDGTNVAVT---QVFIKVLDNNDNGPE-----FSQPNYDVTISEDVLPDTEILQIEA 1484
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSD 442
TD D + R F + P+ ++ A LD E + L + V D
Sbjct: 1485 TDRDEKHKLSYTVHSSIDSISMRKFRID----PSTGVLYTAERLDHEAQDKHILNIMVRD 1540
Query: 443 NYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDG 502
R ++A +++ V D NDH P F+ +Y ++ E A GS V ++A D
Sbjct: 1541 Q-------EFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDK 1593
Query: 503 DSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPK 562
D G NA L Y+I +GN F I G++T D Q VL+I DQG P
Sbjct: 1594 DKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEP--DMTTMGQFVLSIKVTDQGSPPM 1651
Query: 563 VSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSL 622
+ A + +++ ++ P F + Y V EN GT ++++ A T+ + +
Sbjct: 1652 SATAIVRISVTMSDNSHPKFIHKD-YQAEVNENVDIGTSVILISAIS-----QSTLIYEV 1705
Query: 623 QEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDI 682
++ + + F ++P SG ++T +LD E + Y L++ AT++ +S A +N+ ++D
Sbjct: 1706 KDGDING-IFTINPYSGVITTQKALDYERTSSYQLIIQATNMAG--MASNATVNIQIVDE 1762
Query: 683 NDNSPVFYPVQYFAHIKENEPGGSYITT-------VSATDPDLGTNGTVKYSISAGDRSR 735
NDN+PVF QY + E P S + + + ATD D N + Y I +
Sbjct: 1763 NDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKK 1822
Query: 736 F-QVNAQSGVISTRMALDREEKTAYQLQIVATDGGN--LQSPNQAIVTITVLDTQDNPPV 792
F V++ +G I T LD E + + D G+ L + + V I V D DNPPV
Sbjct: 1823 FFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPV 1882
Query: 793 FSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTT 850
F+Q + ++ +G V VSA+ D + ++Y + G F I+ +G LT
Sbjct: 1883 FTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSLDH-FLIDSNSGVLTI 1941
Query: 851 ANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGH 910
N + + Y L V S G +MV I VK+ D+ HF Q+ S ++ EN
Sbjct: 1942 KN--NNLSKDHYMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNIT 1999
Query: 911 SIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLG-PLDVHAGS-YQIEILA 968
+ AV +N + YS+ NP N F I +G I G P D Y++ + A
Sbjct: 2000 KVAIVNAVG--NRLNEPLKYSIL-NPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEA 2056
Query: 969 SDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGAN 1028
S + V++ V + D+NDNSPVF L Y + + ++V A DKD G N
Sbjct: 2057 SRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPN 2116
Query: 1029 GEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQD-RYVLMVVASDRAVEPLSATVNV 1086
GE+ Y + + F I P+ G + +K + +L + Y + ++A D LS +V +
Sbjct: 2117 GEVTYVLQDDY--GHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVEL 2174
Query: 1087 TVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGE-VRYSFEMVQP- 1144
+ + VN P+F+ YT E+ R + + ++A P G+ + Y P
Sbjct: 2175 PITI--VNKAMPVFDKPFYTASVNEDIRMNTPILSINATS----PEGQGIIYIIIDGDPF 2228
Query: 1145 -DFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDI 1203
F + +G + D E T+ + T+ A+D + + TV + + D+
Sbjct: 2229 KQFNIDFDTGVLKVVSPLDYEV------TSAYKLTIRASDA--LTGARAEVTVDLLVNDV 2280
Query: 1204 NDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKG--NEERQFAID 1261
NDN P F + Y T+SE++ T VL+V + D D NN ++HY I++ N F ID
Sbjct: 2281 NDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFHID 2340
Query: 1262 STSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLF 1321
S+SG + LD+E +L ++++DSG L+S ++I I D NDN P F +
Sbjct: 2341 SSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYE 2400
Query: 1322 VDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFE 1381
V E G V+ V A+D+DS D L YSI N+ +F + +G I L+
Sbjct: 2401 SYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQR 2460
Query: 1382 TQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVIS 1441
+ LY LN++ D +ST V I V N P+F + EN+ GT VI
Sbjct: 2461 MEPLYSLNVSVSDG---LFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIH 2517
Query: 1442 VTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQ 1501
V A D D GQ+SY II + + F ID G + T +DRE N E V +
Sbjct: 2518 VRATDGDPGTYGQISYAIINDFAK-DRFLIDS-NGQVITTERLDRE--NPLEGDVSIFVR 2573
Query: 1502 AVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAV-IGSVLTTIMAADPDEGAN 1560
A+ R V ++V D NDN P F++ A+ + V G ++T + A DPD+GAN
Sbjct: 2574 ALD-GGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGAN 2632
Query: 1561 GEIEYEIINGDT----DTFIVDRYSGDLRVASALVP-SQLIYNLIVSATDLGPERRKSTT 1615
I Y + + + D +D +G + + + V A D G + S
Sbjct: 2633 SRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLI 2692
Query: 1616 ELTIILQGLDG--PVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCE 1673
+ I + + P FTQ +Y + E IG+ V ++ + V + V+
Sbjct: 2693 PVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQN----VWFSTVNGERP 2748
Query: 1674 EKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDI 1733
E G +F I + TG I+ LDRE + V A +V+I + D+
Sbjct: 2749 ENNKGGIFVIEQETGTIKLDKRLDRETSPAFHF-KVAATIPLDKVDIVFTVDVDIKVLDL 2807
Query: 1734 NDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGAD-----DSFR 1788
NDN PVF T D + E + G+K+ Q+ A+D D GAN VTY++ S + ++F
Sbjct: 2808 NDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFN 2867
Query: 1789 IDPESGDLIATRRLDRERRSKYSLLVRADDGLQ----SSDMRINITVSDVNDHTPKFSRP 1844
ID +G + + LD E ++ V A D + SS +++ V+D+ND+ P F++
Sbjct: 2868 IDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQE 2927
Query: 1845 VYSFDIPEDTIPGSLVAAILATD-DDSGVNGEITYIVNEDDEDGIFFLNPITGVFNL--T 1901
VY ++ E PG +VA + D D S VN +++Y + + G F L + + +
Sbjct: 2928 VYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVK 2987
Query: 1902 RLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGS 1961
R LD E Q Y L + A DG T V ++ DVNDN P+ +Y+ L E++P
Sbjct: 2988 RPLDREEQDIYFLNITATDGLF-VTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNK 3046
Query: 1962 TVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVH 2021
+L + DAD G N + YS+ + F ++G LK L LDRE Y+L+ +
Sbjct: 3047 IILKVSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKAT 3106
Query: 2022 DLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL-TYIPENTPIDTVVFKAQATDPDSG 2080
D RF + + +IL DVNDNPP F S T + ENT ++ + QA DPD G
Sbjct: 3107 D----GGGRFCQS-NIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIG 3161
Query: 2081 PNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQ-PSLSSSTE 2139
N + Y+L + G FSI + G + L LDRE+ S+Y ++V ATD+ SLSS T
Sbjct: 3162 INRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTT 3221
Query: 2140 VVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTN 2199
V + VLDINDN P+F + Y V + E+T GT ++ VFA D GTN ++ Y I +GN
Sbjct: 3222 VTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQ 3281
Query: 2200 QEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVF 2259
+F+I+ TG I+V++ LD E ++L V+A D G+ + +TV+I L D+ND P F
Sbjct: 3282 GKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKF 3341
Query: 2260 ELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGELGV 2318
YS + E+ + +++ ++A D D N ++ + + G+ DN FT+ G + V
Sbjct: 3342 SQDVYSAVISED-ALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKV 3400
Query: 2319 TQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAP 2378
+ LDRE + L++ A DSG PA++ T T+N+ + DVNDN P F Y I E+ P
Sbjct: 3401 KKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKP 3460
Query: 2379 TGTDVLLVNASDADASKNA---VIRIIGGN--SQFTINPSTGQIITSALLDRETKD-NYT 2432
GT +L + +D D+ N I+ GN +F ++P I+ SA++ + T+ Y
Sbjct: 3461 VGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPH--GILRSAVVFQHTESLEYV 3518
Query: 2433 LVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTD 2492
L V D+G P+ + S T + V V + + + P PG + + TD
Sbjct: 3519 LCVQAKDSGKPQQV-SHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATD 3577
Query: 2493 ADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTD-- 2550
D+ L ++L F ++ G I+A G L+ V +V V DG D
Sbjct: 3578 QDM--YDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYV-LNVSVSDGRFQVPIDVV 3634
Query: 2551 -----------STTVTVRFVN 2560
TVT+RF N
Sbjct: 3635 VHVEQLVHEMLQNTVTIRFEN 3655
Score = 764 bits (1972), Expect = 0.0
Identities = 665/2292 (29%), Positives = 1059/2292 (46%), Gaps = 146/2292 (6%)
Query: 25 LRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPG-----FTYRLSESHA 79
L + W+ P + EP F V+E +VG + +P F +
Sbjct: 1345 LHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDS 1404
Query: 80 LFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPS 139
F G + +D E +++ V T+V + V D NDN P F P+
Sbjct: 1405 AFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPN 1464
Query: 140 IVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAF 199
VT ED +++ ATD D + + + + I +FR+D +
Sbjct: 1465 YDVTISEDVLPDTEILQIEATDRD-EKHKLSYTVHSSIDSISMRKFRIDPSTGV------ 1517
Query: 200 LHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGV 259
L + LD E ++ L + V D+ P RR +V V V+D ND+ P F + Y+A V
Sbjct: 1518 --LYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASV 1575
Query: 260 PEDAVVGSSVLQVAAADADEGTNADIRYRLQ--DEGTPFQMDPETGLITVREPLDFEARR 317
E A +GS+VLQV A D D+G NA++ Y ++ + G F+++P G+IT+ + D
Sbjct: 1576 FESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMG 1635
Query: 318 QYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVV 377
Q+ L+++ D+G P ++ A I + +++ P F A V+EN +GT V
Sbjct: 1636 QFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHP-----KFIHKDYQAEVNENVDIGTSV 1690
Query: 378 ALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLT 437
L+ S + + ++ G+ F + P +I ALD ER SY L
Sbjct: 1691 ILI------SAISQSTLIYEVKDGDINGIFTIN----PYSGVITTQKALDYERTSSYQLI 1740
Query: 438 VSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG- 496
+ ++ G A V I + D ND+ PVF Y +LSE AP S V
Sbjct: 1741 IQATNMAGMASNATVN---------IQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSL 1791
Query: 497 ------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVL 550
I ATD DS NA L Y IV +F + +G + T LD E +
Sbjct: 1792 DNSPLVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRT--IANLDHETIAHFHF 1849
Query: 551 NISARDQGVHPKV---SYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRA 607
++ RD G P++ S ++ + + DVND PVF+Q ++ ++ G E+L + A
Sbjct: 1850 HVHVRDSG-SPQLTAESPVEVNIEVTDVNDNPPVFTQAV-FETILLLPTYVGVEVLKVSA 1907
Query: 608 TDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSP 667
TD D + +SL E D F +D SG L TI + + + Y L+V +D G
Sbjct: 1908 TDPDSEVPPELTYSLMEGSLDH--FLIDSNSGVL-TIKN-NNLSKDHYMLIVKVSD-GKF 1962
Query: 668 PQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYS 727
+SM I V + D+ F Y I EN + + V+A L N +KYS
Sbjct: 1963 YSTSMVTIMVK--EAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRL--NEPLKYS 2018
Query: 728 ISAGDRSRFQVNAQSGVI-STRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDT 786
I ++F++ + SGVI +T + DREE+ Y+L + A+ + + +V + + D
Sbjct: 2019 I-LNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDI 2077
Query: 787 QDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTG 846
DN PVF + Y V + G + V+A D N D G F IN +G
Sbjct: 2078 NDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSG 2137
Query: 847 QLTTANVIDREEQSF-YQLKVVA-SGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVE 904
+ + + + Y + ++A GG + T V + + +N P F + + +V E
Sbjct: 2138 NVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNE 2197
Query: 905 NWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGS-YQ 963
+ + I A P+ G++ + +P F I+ G + ++ PLD S Y+
Sbjct: 2198 DIRMNTPILSINATSPEG--QGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYK 2255
Query: 964 IEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDK 1023
+ I ASD + + V + + V+DVNDN P+FDQ +Y TLSE+ + + +V + D
Sbjct: 2256 LTIRASD-ALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDA 2314
Query: 1024 DSGANGEIAYTIAEG--NTGDAFGIFPDGQLYIKSE-LDRELQDRYVLMVVASDRAVEPL 1080
DS N + Y I + N+ D F I L + + LD EL L V + D L
Sbjct: 2315 DSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSL 2374
Query: 1081 SATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF- 1139
S+ V V + + DVNDN P+FN Y Y E G FV V A D D + YS
Sbjct: 2375 SSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSIL 2434
Query: 1140 -EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHV 1198
+ F + + SG IT ++ ++R ++S V +D G+ A VH+
Sbjct: 2435 SGNDRTSFLMDSKSGVITLSNH------RKQRMEPLYSLNVSVSD-GL---FTSTAQVHI 2484
Query: 1199 YMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQF 1258
+ N +P F + Y A + E+ A T+V+ V A+D D G G I Y+II + +F
Sbjct: 2485 RVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRF 2544
Query: 1259 AIDSTSGQVTLIGKLDYE--ATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFP 1316
IDS +GQV +LD E S+ ++A+D G + CT+ + ++DENDN P F
Sbjct: 2545 LIDS-NGQVITTERLDRENPLEGDVSIFVRALDGG--GRTTFCTVRVIVVDENDNAPQFM 2601
Query: 1317 KSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI---TGTNNHGTFSISPNTGSIF 1373
V ++ G LV+ V A D D G N+ + YS+ + I P+ G +
Sbjct: 2602 TVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMV 2661
Query: 1374 LAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENI 1433
+ ++ + A D G P + S + V IHV PSF +I E+
Sbjct: 2662 TKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDT 2721
Query: 1434 PIGTSVISVTAHDPD----ADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFA 1489
IG++V ++ + +NG+ + +G F I++ GTI + +DRE +
Sbjct: 2722 AIGSTVDTLRILPSQNVWFSTVNGER-----PENNKGGIFVIEQETGTIKLDKRLDRETS 2776
Query: 1490 NLFELTVKANDQAVPIETRRYALK-NVTILVTDLNDNVPMF-ISQNALAADPSAVIGSVL 1547
F V A +P++ +V I V DLNDN P+F S +G+ L
Sbjct: 2777 PAFHFKVAA---TIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKL 2833
Query: 1548 TTIMAADPDEGANGEIEYEIINGD-----TDTFIVDRYSGDLRVASAL-VPSQLIYNLIV 1601
T + A D D GANG++ Y + + + F +D +G + L + + V
Sbjct: 2834 TQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSV 2893
Query: 1602 SATDLGPERRKSTTELTIILQ---GLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRG 1658
A+DLG S+T L + + PVF Q Y +KE +P G V+++ + R
Sbjct: 2894 VASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPG-EVVAVLSTWDRD 2952
Query: 1659 S---EAPVEYYIVSVRCEEKTVGRLFTIG--RHTGIIQTAAILDREQGACLYLVDVYAIE 1713
+ V Y+I + F +G + + LDRE+ +Y +++ A +
Sbjct: 2953 TSDVNRQVSYHITGGNPRGR-----FALGLVQSEWKVYVKRPLDREE-QDIYFLNITATD 3006
Query: 1714 KSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANA 1773
+A VE+++ D+NDN PV + E+I I++++A DAD G+N
Sbjct: 3007 GLF----VTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNG 3062
Query: 1774 LVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA-DDGLQSSDMRINITVS 1832
+ Y++ + F +DPESG+L LDRER YSL+ +A D G + I++ +
Sbjct: 3063 YIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGGRFCQSNIHLILE 3122
Query: 1833 DVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLN 1892
DVND+ P FS Y+ + E+T +L+ + A D D G+N ++ Y + D G+F ++
Sbjct: 3123 DVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSL-ADSAGGVFSID 3181
Query: 1893 PITGVFNLTRLLDYEVQQYYILTVRAED---GGGQFTTIRVYFNILDVNDNPPIFSLNSY 1949
+G+ L + LD E Q Y ++VRA D G + V +LD+NDNPP+F Y
Sbjct: 3182 SSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDY 3241
Query: 1950 STSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLKALDR 2008
++ E+ G+ VL T D G N+++TY I SG+ G+F ++ K G + V + LD
Sbjct: 3242 LVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDY 3301
Query: 2009 ESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT-YIPENTPIDT 2067
E + LVV+ D PA ++ A V+I L DVNDNPP F + I E+ +
Sbjct: 3302 ELCKRFYLVVEAKD-GGTPA--LSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGD 3358
Query: 2068 VVFKAQATDPDSGPNSYIEYTLLN-PLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVA 2126
V A D DS PN I ++++N N+F++ + G V++ +LDRE VS Y+L V A
Sbjct: 3359 SVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQA 3418
Query: 2127 TDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTN 2186
D G P++SS+ V + + D+NDN+P+F A Y I EN GT I+Q+ D D N
Sbjct: 3419 VDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHN 3478
Query: 2187 G-QVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTV 2245
G + I++GN +EF +D G + A ++ Y L VQA D G + + +
Sbjct: 3479 GPPFSFSILSGNEEEEFVLDP-HGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYI 3537
Query: 2246 SIVLLDINDFVP 2257
+ +++ + P
Sbjct: 3538 RVRVIEESTHKP 3549
Score = 117 bits (294), Expect = 2e-25
Identities = 52/118 (44%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
Query: 3859 CEIDIDECLPSPCHSGGTCHNLV-GGFSCSCPDGFTGRACERDINECLQSPCKNGAICQN 3917
C + D C SPC GG+C L GG+ C+C FTGR CE +I C +PC+NG C
Sbjct: 4018 CVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDP 4077
Query: 3918 FPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCEL 3975
+F C CK G TG CE +N CE C NGGSC + S+ C+C G G++C L
Sbjct: 4078 IGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGL 4135
Score = 109 bits (273), Expect = 6e-23
Identities = 51/132 (38%), Positives = 64/132 (48%), Gaps = 21/132 (15%)
Query: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
D+C PCQ+GGSC P + C CL + G CE +I
Sbjct: 4023 DACKRSPCQHGGSC---------------------TGLPSGGYQCTCLSQFTGRNCESEI 4061
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 3923
C P+PC +GG+C + F C+C G TG CE DINEC + C+NG C N GSF
Sbjct: 4062 TACFPNPCRNGGSCDPIGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFL 4121
Query: 3924 CVCKTGYTGKMC 3935
C C GY G+ C
Sbjct: 4122 CNCTPGYVGQYC 4133
Score = 99.8 bits (247), Expect = 6e-20
Identities = 87/348 (25%), Positives = 142/348 (40%), Gaps = 53/348 (15%)
Query: 4159 CPRLEGACTRSPCQHGGTCMDYWSWQQ---CHCKEGLTGKYCEKSVTPDTALSLEGKGRL 4215
CP C PC C+ Y + ++ C C G G+ + T+LS G +
Sbjct: 3792 CPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLGE-----CSGHTSLSFAGNSYI 3846
Query: 4216 DYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQESSNYTTVKIKN 4275
Y +S+N K E L ++ RT NG++++ + ++ +KI +
Sbjct: 3847 KYRLSENSKEEDF----------------KLALRLRTLQSNGIIMYTR-ANPCIILKIVD 3889
Query: 4276 GKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDR---------IYNR 4326
GK++F D G +G I V DG WH+ + N T LS+D +Y +
Sbjct: 3890 GKLWFQLDCG-SGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQ 3948
Query: 4327 DIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSGKHSLAS 4386
+ + + G V ++ + + + +GF GC+ S+ LP K S +
Sbjct: 3949 TLSTESSIYFGALVQADNIRSLTDTRVTQ--VLSGFQGCLDSVILNNNELPLQNKRSSFA 4006
Query: 4387 ISKTDPSVKIGC-RGPNICASNPCWG------------DLLCINQWYAYRCVPP-GDCAS 4432
+K+GC P+ C +PC C++Q+ C C
Sbjct: 4007 EVVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFP 4066
Query: 4433 HPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEM-VVACLGVLCPQGKVC 4479
+PC+NGGSC+P + + F C+C TG TCE + C C G C
Sbjct: 4067 NPCRNGGSCDP-IGNTFICNCKAGLTGVTCEEDINECEREECENGGSC 4113
Score = 80.9 bits (198), Expect = 3e-14
Identities = 87/307 (28%), Positives = 130/307 (42%), Gaps = 37/307 (12%)
Query: 3914 ICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDS---YYCHCPFGVFG 3970
+C F + C C G +C S + C PC C S S + C CP G G
Sbjct: 3775 VCPRFYRNVRCTCNGG----LCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG 3830
Query: 3971 KHCELNSYGFEELSYMEFPSLDPNNNYIYVKFA----TIKSHALLLYNYDNQTGDRAEFL 4026
+ S F SY+++ L N+ K A T++S+ +++Y N +
Sbjct: 3831 ECSGHTSLSFAGNSYIKY-RLSENSKEEDFKLALRLRTLQSNGIIMYTRANPC------I 3883
Query: 4027 ALEIAEERLRFSYNLGSGTYKL-TTMKKVSDGHFHTVIARRAGMAASLTVDSC--SENQE 4083
L+I + +L F + GSG L + + V+DG +H+V SL++D +
Sbjct: 3884 ILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRA 3943
Query: 4084 PGYCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGR- 4142
P Y + S + VQ + IRSL R V S F GC+ +N
Sbjct: 3944 PLYFQTLSTESSIYFGALVQADN-----IRSLTDT--RVTQVLS-GFQGCLDSVILNNNE 3995
Query: 4143 -PLEPSQALAAQ--GILDQ---CPRLEGACTRSPCQHGGTCMDYWS-WQQCHCKEGLTGK 4195
PL+ ++ A+ G+ + C AC RSPCQHGG+C S QC C TG+
Sbjct: 3996 LPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGR 4055
Query: 4196 YCEKSVT 4202
CE +T
Sbjct: 4056 NCESEIT 4062
Score = 37.4 bits (85), Expect = 0.38
Identities = 12/32 (37%), Positives = 20/32 (62%)
Query: 4166 CTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYC 4197
C R C++GG+C++ + C+C G G+YC
Sbjct: 4102 CEREECENGGSCVNVFGSFLCNCTPGYVGQYC 4133
Score = 35.4 bits (80), Expect = 1.4
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 23/66 (34%)
Query: 3794 SGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPG 3853
+GV E D + C C+NGGSC+ FLC C PG
Sbjct: 4091 TGVTCEE-DINECEREECENGGSCVNVFG----------------------SFLCNCTPG 4127
Query: 3854 YAGSWC 3859
Y G +C
Sbjct: 4128 YVGQYC 4133
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 1242 bits (3214), Expect = 0.0
Identities = 1120/3888 (28%), Positives = 1794/3888 (46%), Gaps = 300/3888 (7%)
Query: 174 YRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGG----LDREVTPQYQLLVEVEDKGEPK 229
Y+I+ G+ F+ + + G+ FL + +KGG L+REV Y L+V+ +K
Sbjct: 72 YKIVSGDSENLFKAEEYI--LGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNT-N 128
Query: 230 RRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL 289
+V V V D ND P+F + Y +PE+ + +S+ +V+A DAD GTN + Y
Sbjct: 129 VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSF 188
Query: 290 QDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVP-----SLTGRAEALIQLL 344
+D F + P +G+I + LD+ + Y + + A DRG+ ++ A+ + +
Sbjct: 189 KDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIE 248
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNI-SVQILGGNE 403
N+ PV+ T + +D + A++TV D D ANG+I S+ I+ G+
Sbjct: 249 QANECAPVIT----AVTLSPSELDRDP----AYAIVTVDDCDQ-GANGDIASLSIVAGDL 299
Query: 404 QRHFE-VQSSKVPNLSLIKVASALDRERIP-SYNLTVSVSDNYGAPPGAAVQARSSVASL 461
+ F V+S +K +D + P YNLT+ D G PP SSV +
Sbjct: 300 LQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDK-GTPPQF-----SSVKVI 353
Query: 462 VIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLG 521
+ P F + VYR +SE APP + V + A S +LRY S G
Sbjct: 354 HVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYS----HLRYVFKSTPGKA 409
Query: 522 WFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPV 581
F ++ ++GL++ + R+ A+ L ++ D+ KV +V +L N P
Sbjct: 410 KFSLNYNTGLISILEP--VKRQQAAHFELEVTTSDRKASTKV-----LVKVLGANSNPPE 462
Query: 582 FSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRL 641
F+Q Y + EN P GT ++ L A D D G+NG V +S+ A + F +D +G +
Sbjct: 463 FTQT-AYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSI--ANLNHVPFAIDHFTGAV 519
Query: 642 STISSLDREEQA-FYSLLVLATDLGSPPQSSMARI-NVSLLDINDNSPVFYPVQYFAHIK 699
ST +LD E Y+L + A+D G P + + + ++L ++NDN+P+F + I
Sbjct: 520 STSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIP 579
Query: 700 ENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDR---EE 755
+ G ITTVSA D D V+Y I AG+ F +N SGV+S + +L +
Sbjct: 580 RDLGVGEQITTVSAIDAD--ELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAK 637
Query: 756 KTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDN-------------------------- 789
+ + L+I ATDG N +P +T+ N
Sbjct: 638 VSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQG 697
Query: 790 ----------------PPVFSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLIT 831
P S + V EN +G V ++++ +D N + Y ++
Sbjct: 698 EVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVS 757
Query: 832 TGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDT---MVNITVKDLND 888
G++ F I+ TG L + +DRE Y L + + ++++ V D ND
Sbjct: 758 GGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDAND 817
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGT 948
N P FLQ V V E+ + I Q +A D D G NG V YS+ + + F+I+ G
Sbjct: 818 NPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDT-DTFSIDSVTGV 876
Query: 949 ISLLGPLD---VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTL 1005
+++ PLD H S +IE PQL S+V++ V + DVNDN P F +Y V +
Sbjct: 877 VNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKV 936
Query: 1006 SESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDR 1065
E P + ++A D D G +G++ Y++ + G+ G + I +LD E +
Sbjct: 937 REDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQV 996
Query: 1066 YVLMVVASDRAVE-PLSATVNVTVILEDVNDNR--PLFNSTNYTFYFEEEQRAGSFVGKV 1122
Y L V A D+ LS+T V V + DVN+N P+F+S +E+ GS V V
Sbjct: 997 YNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTV 1056
Query: 1123 SAVDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
SA D+D +GE+RYS F++ +G I + + DRES T+ + TV
Sbjct: 1057 SAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRES------TSHYWLTVF 1110
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEG 1240
ATDQG+ PL +++ ++D+NDNAP+ + Y I E++ V+++ A D D
Sbjct: 1111 ATDQGVV-PLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSS 1169
Query: 1241 NNGLIHYSIIKGNEERQFAIDSTSGQVTLIG-KLDYEATPAYSLVIQAVDSGTIPLNSTC 1299
+N + Y I GN + F+I +G +T KLD E + L + D+G+ P ++
Sbjct: 1170 SNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIA 1229
Query: 1300 TLNIDILDENDNTPSFPKSTLFVDVLENMRIG-------ELVSSVTATDSDSGDNADLYY 1352
+ + ILDENDN P F + + + E + E + V ATD D G NA++ Y
Sbjct: 1230 RVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISY 1289
Query: 1353 SITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYK-LNITAKDQGRPPRSSTMSVVIHVR 1411
SI N HG F I P TG + + F Y L+I A D GRP +SST +H+
Sbjct: 1290 SIEDGNEHGKFFIEPKTGVVSSKR---FSAAGEYDILSIKAVDNGRPQKSSTTR--LHIE 1344
Query: 1412 DFNDNPPSFPPGDIFKS-----IVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRG 1466
+ PS P +S ++E+ P+ + ++ P + + I
Sbjct: 1345 WISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPL-----WFDITGGNYD 1399
Query: 1467 NHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNV 1526
+HF +D+ GTI +D E + + LTV+A D I T+ V I V D ND+
Sbjct: 1400 SHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQ------VFIKVIDTNDHR 1453
Query: 1527 PMFISQNALAADPSAVIGSV-LTTIMAADPDEGANGEIEYEIING----DTDTFIVDRYS 1581
P F + P + I A D DE ++ Y + + F +D +
Sbjct: 1454 PQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTLQSSRDPLSLKKFRLDPAT 1511
Query: 1582 GDLRVASAL---VPSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITIL 1638
G L + L Q ++V D+ +R + + + P FT Y +
Sbjct: 1512 GSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRV 1571
Query: 1639 KEGEPIGTNVISIEAASP-RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILD 1697
E +G+ V+ + A +G A V Y I E +G F I G I+TA LD
Sbjct: 1572 YESAAVGSVVLQVTALDKDKGKNAEVLYSI-----ESGNIGNSFMIDPVLGSIKTAKELD 1626
Query: 1698 REQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGS 1757
R A Y + V A +K + P ++ V I + ++ P F + + + E + GS
Sbjct: 1627 RSNQA-EYDLMVKATDKGSP-PMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGS 1684
Query: 1758 KIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA 1816
+ +TA + + V Y I G D+F I+P SG +I + LD E Y+L+++
Sbjct: 1685 FVGMVTAH-----SQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQG 1739
Query: 1817 DD--GLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAA-------ILATD 1867
+ GL S++ + + + D ND+ P F + Y+ I E S+V I A D
Sbjct: 1740 TNMAGL-STNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAAD 1798
Query: 1868 DDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFT- 1926
D N + Y + E F ++ TG + LDYE + TV+ D G
Sbjct: 1799 ADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLF 1858
Query: 1927 ---TIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI 1983
V +++D+ND PP+F+ Y SL+ G V+ N TDAD SQL YSI
Sbjct: 1859 AEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSI 1918
Query: 1984 ASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILL 2042
G+ +F++D K G L V S+ Y L V+ D RF V I +
Sbjct: 1919 TEGNIGEKFSMDYKTGALTVQNTTQLRSR--YELTVRASD------GRFAGLTSVKINVK 1970
Query: 2043 DVNDNPPTFLSPKLTYIPE--NTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
+ ++ F + + + +T +T+ +P + P + Y +LNP +F I
Sbjct: 1971 ESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEP---LFYHILNP-DRRFKIS 2026
Query: 2101 TIDGEVRLTGE-LDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 2159
G + TG DRE+ + + V T++ +PS + V V+V D NDN P+F Y
Sbjct: 2027 RTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPY 2086
Query: 2160 KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDR 2219
+ +T G I V A D D G NG+V Y + + + F+I + G I++ K +
Sbjct: 2087 YAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHH--EHFQIGPL-GEISLKKQFEL 2143
Query: 2220 EK-TPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT 2278
+ Y +TV A D G+ + V I ++ N +PVFE YS + E++ +
Sbjct: 2144 DTLNKEYLVTVVAKDGGNPAFSAEVIVPITVM--NKAMPVFEKPFYSAEIAESI-QVHSP 2200
Query: 2279 ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSAS-GELGVTQSLDRETKERFVLMITAT 2337
++ V A + K+ Y + G+ + FT++ + G + V LD E + L I AT
Sbjct: 2201 VVHVQANSPE---GLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRAT 2257
Query: 2338 DSGSPALTGTGT---INVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADAS 2394
DS LTG +++IVDD+NDN P FA ++Y T+ E + GT V+ V A+D+D+
Sbjct: 2258 DS----LTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSE 2313
Query: 2395 KNAVI--RIIGGNSQ----FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSS 2448
N I ++ G +S+ F ++ STG I LD E +T+ V D G P LSS
Sbjct: 2314 PNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPT-LSS 2372
Query: 2449 STSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSG 2507
V V VTD+NDNPP F+ Y I G FV V DAD +L YS LSG
Sbjct: 2373 DVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSG 2432
Query: 2508 RNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK-DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ + F ID G I + A + +S+++ G F + VTV N P
Sbjct: 2433 NDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHS-PA 2491
Query: 2567 VRAKEQTFMFPENQPVSSLV----TTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVS 2622
E EN P+ +LV TT S + G ++Y+I + + F I++ GQ+
Sbjct: 2492 FLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH-VTYHIVNDFAKDRFYINE-RGQIF 2549
Query: 2623 ISQPLDFEKIQKYVVWIE--ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILE 2680
+ LD E + V+ + A+D G ++ +++ + D NDNAP F+ + I
Sbjct: 2550 TLEKLDRETPAEKVISVRLMAKDAGGKV--AFCTVNVILTDDNDNAPQFRATKYEVNIGS 2607
Query: 2681 NLSP-RKILTVSAMDKDSGPNGQLDYEIV--NGNMENSFSINHATGEIRSVRPLDREKVS 2737
+ + ++ V A D D G N + Y I + +++ + IN +G I + L +
Sbjct: 2608 SAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENE 2667
Query: 2738 HYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAH-VPENSPLGYTVTRVTT 2796
+ +++ D GSPS+ + V V + IL P+FS+ F V E+ P+G + +
Sbjct: 2668 FFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRA 2727
Query: 2797 SDEDIGINAISRYSIMDASLP-------FTINPSTGDIVISRPLNREDTDRYRIRVSAH- 2848
+ YS++ + P F I+ +G + + + L+ E T Y+ + A
Sbjct: 2728 EHSGTVL-----YSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARC 2782
Query: 2849 ---DSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG 2905
D S DV+I V D NDN+P F + Y E GS+V Q+ A+D D G+NG
Sbjct: 2783 TQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNG 2842
Query: 2906 QVFYFI-KSQS----EYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK 2960
QV Y + +SQS E F IN TG I + L ++ + + V +SD G+
Sbjct: 2843 QVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKR--------DNYQIKVVASDHGE 2894
Query: 2961 PSLISETTVT-INIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEV 3019
+S T + + + D ND+ P+F Y V+++ G + ++ D +N +V
Sbjct: 2895 KIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQV 2954
Query: 3020 EYFISNDNHLGKFKLDN-DTGW-ISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHI 3077
YFI+ + LG+F ++ W + V L + N+ +T+TA D SS+A V +
Sbjct: 2955 TYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDG---TFSSKAIVEV 3011
Query: 3078 TVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSI-SSGNEEGI 3136
V + N ++P ++ S TIPE G ++ +SA D D N I Y++ SG E+
Sbjct: 3012 KVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEK-- 3069
Query: 3137 FAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLS 3196
F +N TG L + LD E + + + A DGG R S+ + + DVNDN+P F +
Sbjct: 3070 FKLNPDTGELKTSTPLDREEQAVYHLLVRATDGG--GRFCQASIVLTLEDVNDNAPEFSA 3127
Query: 3197 DDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFL 3256
D Y TV EN GT + + ATDAD+G N I Y++ S F I+ +G+I + L
Sbjct: 3128 DPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPL 3187
Query: 3257 DFETKQSYHLTVKAFNVPDEERCSFA-TVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGT 3315
D E + Y L++KA + R + TV + + N+ P F + Y +SE GT
Sbjct: 3188 DRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGT 3247
Query: 3316 IVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLA 3375
V +V+A+ RD+ + E+ Y I + F I+ KTG +++ LD E L V A
Sbjct: 3248 EVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEA 3307
Query: 3376 KNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSI 3434
+ G+ +D+ TVNV V D ND P+F+ + Y+ ISE + V V A D+D
Sbjct: 3308 TDGGTPSLSDV--ATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADG- 3364
Query: 3435 PSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSA 3494
PS S Y I GN+ +F+I+P G++ VT LDRET+ Y L+V A D+G+P +
Sbjct: 3365 PSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTT 3424
Query: 3495 SLLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTG 3552
++ + + D+NDN P+ + V+ ENK G V+ L TD D N PF ++ + TG
Sbjct: 3425 TVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPF-FFTIVTG 3483
Query: 3553 PATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPS 3612
F ++ GVL T+ I R++ + L V D+G PQ+SS + I VI+++ P
Sbjct: 3484 NDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPP 3543
Query: 3613 QSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVTSLFSIPGGTCDLNSQP 3672
+EIF+ G + GG++G + D DV D+ SL + +LFS+ L +
Sbjct: 3544 AILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYSLDPQMDNLFSVSSTGGKLIAHK 3603
Query: 3673 RSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNHYLH 3732
+ G + L V DG +TV ++I V + ++++I +R T ++F+ +++ +
Sbjct: 3604 KLDIGQYLLNVSVTDGKFTTV-ADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRN 3662
Query: 3733 FLRIASSQLTGLGTAVQLYS--AYEENNRTFLLAAVKRNHNQYVNPSGVATFFESIKEIL 3790
F R + L +Q+ S + E + +L V++ + ++ + S +
Sbjct: 3663 FQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDI 3722
Query: 3791 LRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAV-SSVLKSRESLPVIIVANEPLQPFLCK 3849
GV++ +V C C C +++V SV+ + + + V + +C
Sbjct: 3723 EEIIGVRILNVFQKLCAGLDCP-WKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCL 3781
Query: 3850 CLPGYAGSWCEIDIDECLPSPCHSGGTCHN--LVGGFSCSCPDGFTGR 3895
C G C C PC G C + +C CP G G+
Sbjct: 3782 CKEGR----CPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQ 3825
Score = 1130 bits (2922), Expect = 0.0
Identities = 977/3345 (29%), Positives = 1555/3345 (46%), Gaps = 250/3345 (7%)
Query: 50 QVLEEQPPGTLVGTIQTRPGFT-----YRLSESHALFAINSSTGALYTTSTIDRESLPSD 104
++ E PP T V ++ P ++ ++ + A F++N +TG + + R+
Sbjct: 375 EISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAH- 433
Query: 105 VINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDI 164
L V +S T+V V V N N P F + F E+ G V+ +A D D
Sbjct: 434 -FELEVTTSDRKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDE 492
Query: 165 GSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKG-GLDREVTPQ-YQLLVEV 222
G NG + +Y I N P F VS LD E+ P+ Y L +
Sbjct: 493 GENG--YVTYSIANLNHV----------PFAIDHFTGAVSTSENLDYELMPRVYTLRIRA 540
Query: 223 EDKGEPKRRGY-LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGT 281
D G P RR + +T+ ++NDN P+F + + +P D VG + V+A DADE
Sbjct: 541 SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQ 600
Query: 282 NADIRYRLQDEGTPFQMDPETGLITVREPL---------------------DFEARRQYS 320
+ +E F ++P +G+++++ L +F +
Sbjct: 601 LVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYIN 660
Query: 321 LTVQAMDRGVP---SLTGRAEALIQ-LLDVN--DNDPVVKFRYFPATSRYA--------- 365
+TV A + V TG A+ L + LL N N V+ +F + S A
Sbjct: 661 ITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL 720
Query: 366 ----SVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIK 421
V EN VG+ V + TD D+ NG + + GGNE F + ++K
Sbjct: 721 PTGIQVKENQPVGSSVIFMNSTDLDT-GFNGKLVYAVSGGNEDSCFMIDM----ETGMLK 775
Query: 422 VASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYR 481
+ S LDRE Y L ++V D G P AA + L + V D ND+PP F Q+ Y
Sbjct: 776 ILSPLDRETTDKYTLNITVYD-LGIPQKAAWRL------LHVVVVDANDNPPEFLQESYF 828
Query: 482 VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLD 541
V +SE+ S + + ATD D G N ++ YSIV+ F I +G+V LD
Sbjct: 829 VEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDT--FSIDSVTGVVNIARP--LD 884
Query: 542 RELASQIVLNISARDQGVHPKVSYAQLV--VTLLDVNDEKPVFSQPEGYDVSVVENAPTG 599
REL + L I ARDQ ++ +V V+L DVND P F P Y V V E+ P G
Sbjct: 885 RELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFI-PPNYRVKVREDLPEG 943
Query: 600 TELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLV 659
T ++ L A D DLG +G VR+SL + +F +D +SG + + LD E++ Y+L V
Sbjct: 944 TVIMWLEAHDPDLGQSGQVRYSL--LDHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTV 1001
Query: 660 LATDLGSPPQ-SSMARINVSLLDINDN--SPVFYPVQYFAHIKENEPGGSYITTVSATDP 716
A D G P SS + V ++D+N+N PVF +KE+ P GS + TVSA D
Sbjct: 1002 RAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDE 1061
Query: 717 DLGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPN 775
D +G ++YSI G F++ ++GVI T LDRE + Y L + ATD G + +
Sbjct: 1062 DARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSS 1121
Query: 776 QAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTG 833
+ I V D DN P S+ Y + EN V + A D +SN + Y IT+G
Sbjct: 1122 FIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSG 1181
Query: 834 DQKGMFAINQVTGQL-TTANVIDREEQSFYQLKV-VASGGTVTGDTMVNITVK--DLNDN 889
+ +G F+I+ TG + TT+ +DRE+Q + L+V V G+ T+ + VK D NDN
Sbjct: 1182 NPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDN 1241
Query: 890 SPHFLQAIESVNVVENWQAGHS-------IFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFA 941
P FLQ + + E + ++ A D DEG N + YS++ N F
Sbjct: 1242 KPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFF 1301
Query: 942 INEKNGTISLLGPLDVHAGSYQI-EILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLS 1000
I K G +S AG Y I I A D G PQ SS+ L ++ ++ P + +S
Sbjct: 1302 IEPKTGVVS--SKRFSAAGEYDILSIKAVDNGRPQKSSTTRL--HIEWISKPKPSLEPIS 1357
Query: 1001 YE-----VTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYI 1054
+E T+ ES+PV + + + I GN F + G + +
Sbjct: 1358 FEESFFTFTVMESDPVAHMIGVISVEPPGI----PLWFDITGGNYDSHFDVDKGTGTIIV 1413
Query: 1055 KSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQR 1114
LD E + Y L V A+D L+ V + + D ND+RP F+++ Y E+
Sbjct: 1414 AKPLDAEQKSNYNLTVEATDGTTTILT---QVFIKVIDTNDHRPQFSTSKYEVVIPEDTA 1470
Query: 1115 AGSFVGKVSAVDKDFGPNGEVRYSFE-----MVQPDFELHAISGEITNTHQFDRESLMRR 1169
+ + ++SAVD+D ++ Y+ + + F L +G + + + D E++ +
Sbjct: 1471 PETEILQISAVDQD--EKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQH 1528
Query: 1170 RGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQV 1229
+ TV+ DQ +P ++ A + V + D ND+AP F Y+ + ESAA + V
Sbjct: 1529 ------TLTVMVRDQDVPVK-RNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVV 1581
Query: 1230 LRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVD 1289
L+V+A D D+G N + YSI GN F ID G + +LD Y L+++A D
Sbjct: 1582 LQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATD 1641
Query: 1290 SGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNAD 1349
G+ P++ ++ I + ++ +P F V++ E + IG V VTA S
Sbjct: 1642 KGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQSS----- 1696
Query: 1350 LYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIH 1409
+ Y I N F I+P++G+I K LDFET +Y L I + S+ +V++H
Sbjct: 1697 VVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMA--GLSTNTTVLVH 1754
Query: 1410 VRDFNDNPPSFPPGDIFKSIVENIPIGTSVIS-------VTAHDPDADINGQLSYTIIQQ 1462
++D NDN P F + I E+ I + V++ + A D D D N L Y I++
Sbjct: 1755 LQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEP 1814
Query: 1463 MPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDL 1522
+F ID G I+T +D E ++F TV+ +D P YA NVT+ V D+
Sbjct: 1815 SVH-TYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYA-ANVTVHVIDI 1872
Query: 1523 NDNVPMFIS--QNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDR 1579
ND P+F A P+ G + T+ A D D A ++ Y I G+ + F +D
Sbjct: 1873 NDCPPVFAKPLYEASLLLPT-YKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDY 1931
Query: 1580 YSGDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITILK 1639
+G L V + + Y L V A+D G ++ ++ + FTQ Y ++K
Sbjct: 1932 KTGALTVQNT-TQLRSRYELTVRASD-GRFAGLTSVKINVKESKESHLKFTQDVYSAVVK 1989
Query: 1640 EGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAI-LDR 1698
E + I A +E P+ Y+I++ R F I R +G++ T DR
Sbjct: 1990 ENSTEAETLAVITAIGNPINE-PLFYHILN-------PDRRFKISRTSGVLSTTGTPFDR 2041
Query: 1699 EQGACL-YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGS 1757
EQ +V+V K +A V++ ++D NDN PVF V+ + G
Sbjct: 2042 EQQEAFDVVVEVTEEHKPSA---VAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGH 2098
Query: 1758 KIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSL--LVR 1815
I +TA+D D G N V Y + + F+I P G++ ++ + + +K L +V
Sbjct: 2099 VIRYVTAVDRDSGRNGEVHY-YLKEHHEHFQIGP-LGEISLKKQFELDTLNKEYLVTVVA 2156
Query: 1816 ADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGE 1875
D G + + + ++ +N P F +P YS +I E S V + A +S +
Sbjct: 2157 KDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQA---NSPEGLK 2213
Query: 1876 ITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDG-GGQFTTIRVYFNI 1934
+ Y + + D F +N TGV N+ LD+E Y L++RA D G + V +
Sbjct: 2214 VFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIV 2273
Query: 1935 LDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLG--QF 1992
D+NDNPP+F+ SY+ +L E +G++V+ TD+D N ++Y + S F
Sbjct: 2274 DDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHF 2333
Query: 1993 TVDKN-GVLKVLKALDRESQSFYNLVVQVHD--LPQIPASRFTSTAQVSIILLDVNDNPP 2049
VD + G++ +L+ LD E + + V+ D +P + +S V++ + D+NDNPP
Sbjct: 2334 HVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTL-----SSDVIVTVDVTDLNDNPP 2388
Query: 2050 TFLSPKL-TYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK-FSIGTIDGEVR 2107
F I E+ P V +A D DS ++Y++L+ +K F I + G +
Sbjct: 2389 LFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIIT 2448
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENT 2167
L+ Y+L + +D SST+V V V+ N ++P F Q Y+VE+ EN
Sbjct: 2449 LSNLHRHALKPFYSLNLSVSD---GVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENA 2505
Query: 2168 LTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHL 2227
T +++V DGD G G V Y IVN F I+ G I + LDRE +
Sbjct: 2506 PLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINE-RGQIFTLEKLDRETPAEKVI 2564
Query: 2228 TVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDD 2287
+V+ + + + TV+++L D ND P F + Y VN+ + ++++V+A D
Sbjct: 2565 SVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSS-AAKGTSVVKVLASDA 2623
Query: 2288 DRGSNSKLSYVLFGGNE---DNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPAL 2344
D GSN+ ++Y + +E +N SG + +SL E F + A D+GSP+
Sbjct: 2624 DEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSK 2683
Query: 2345 TGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGG 2404
+ V + +P F+ Y T+ ED P GT++ L+ A+ S + ++ G
Sbjct: 2684 ESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIR---AEHSGTVLYSLVKG 2740
Query: 2405 NS-------QFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVT 2457
N+ F I+ +G++ LD ET Y ++ + +S V + V
Sbjct: 2741 NTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVK 2800
Query: 2458 DVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNS----EKF 2513
D NDN P F+ PY I GS V + +DAD G N ++ YSL S E F
Sbjct: 2801 DANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESF 2860
Query: 2514 HIDPLRGAIMAAGPLNGASEVTFSVHV--KDGGSFPKTDSTT---VTVRFVNKADFPKVR 2568
I+ G I L+ + + V D G + ST VTV VN + P+
Sbjct: 2861 AINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSP-PRFT 2919
Query: 2569 AKEQTFMFPENQP----VSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQ--VS 2622
A+ E+ P ++ L TT S ++Y+I G+ F ++ + + V
Sbjct: 2920 AEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVY 2979
Query: 2623 ISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENL 2682
+ +PLD EK Y++ I A DG FSS +++ VLD NDN+P+ ++ + I E++
Sbjct: 2980 VKKPLDREKRDNYLLTITATDG---TFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDV 3036
Query: 2683 SPRK-ILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVL 2741
P K I+ +SA D D N ++ Y ++ E F +N TGE+++ PLDRE+ + Y L
Sbjct: 3037 LPGKLIMQISATDADIRSNAEITYTLLGSGAE-KFKLNPDTGELKTSTPLDREEQAVYHL 3095
Query: 2742 TIKSSDKGSPSQSTSVKVMINILDENDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDED 2800
++++D G + +++ + D NDNAP FS ++ V EN+ G +TRV +D D
Sbjct: 3096 LVRATDGG--GRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDAD 3153
Query: 2801 IGINAISRYSIMD-ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG----WTVS 2855
G+N YS++D A F+IN +G I + +PL+RE Y + + A D G T +
Sbjct: 3154 AGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTAT 3213
Query: 2856 TDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQS 2915
V + V DINDN P F Y E +G++V QV+A D +N ++ Y I S +
Sbjct: 3214 GTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGN 3273
Query: 2916 EY--FRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINI 2973
E+ F I++ TG +F + L Y+ + + + V ++D G PSL TV +N+
Sbjct: 3274 EHGKFSIDSKTGAVFIIENLDYE--------SSHEYYLTVEATDGGTPSLSDVATVNVNV 3325
Query: 2974 VDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFK 3033
D NDN P F + Y T ++++ + +I V A DD D NS + Y I + N F
Sbjct: 3326 TDINDNTPVFSQDTYTTVISEDAVLEQSVITVMA-DDADGPSNSHIHYSIIDGNQGSSFT 3384
Query: 3034 LDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSH 3093
+D G + V L + + +TV A D G+PP + TV+I V++ N + P FS+ +
Sbjct: 3385 IDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGN 3444
Query: 3094 MSATIPESHSIGSIVRTVSARDRDAAMNG-LIKYSISSGNEEGIFAINSSTGILTLAKAL 3152
S I E+ +G V + D D++ NG ++I +GN+E F +N G+L + A+
Sbjct: 3445 YSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQ-GVLLTSSAI 3503
Query: 3153 DYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTT 3212
+ + + + D G + + + VI+ + P L + F T SG
Sbjct: 3504 KRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGV 3563
Query: 3213 VIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLD 3257
+ ++ATD D + Y++ +LF + G + LD
Sbjct: 3564 IGKIHATDQD--VYDTLTYSLDPQMDNLFSVSSTGGKLIAHKKLD 3606
Score = 1118 bits (2891), Expect = 0.0
Identities = 908/3021 (30%), Positives = 1429/3021 (47%), Gaps = 187/3021 (6%)
Query: 142 VTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLH 201
+ KE+ G VI +TD D G NG Y + GNE F +D+ E L
Sbjct: 724 IQVKENQPVGSSVIFMNSTDLDTGFNG--KLVYAVSGGNEDSCFMIDM------ETGMLK 775
Query: 202 LVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPE 261
++S LDRE T +Y L + V D G P++ + ++V V D NDNPP F Y V E
Sbjct: 776 ILSP--LDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSE 833
Query: 262 DAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSL 321
D V S ++QV A D D G N + Y + + F +D TG++ + PLD E + ++SL
Sbjct: 834 DKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSL 893
Query: 322 TVQAMD--RGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVAL 379
++A D R P L + L DVNDN P + P R V E+ GTV+
Sbjct: 894 KIEARDQAREEPQLFSTVVVKVSLEDVNDNPPT----FIPPNYR-VKVREDLPEGTVIMW 948
Query: 380 LTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVS 439
L D D +G + +L E +F+V +++ LD E+ YNLTV
Sbjct: 949 LEAHDPDL-GQSGQVRYSLLDHGE-GNFDVDKLS----GAVRIVQQLDFEKKQVYNLTVR 1002
Query: 440 VSDNYGAPPGAAVQARSSVASLVIFVNDIND--HPPVFSQQVYRVNLSEEAPPGSYVSGI 497
D G P + SS + + V D+N+ HPPVFS V + + E+AP GS V +
Sbjct: 1003 AKDK-GKP-----VSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTV 1056
Query: 498 SATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQ 557
SA D D+ + +RYSI G+G+G F I E +G++ T S LDRE S L + A DQ
Sbjct: 1057 SAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIET--SDRLDRESTSHYWLTVFATDQ 1114
Query: 558 GVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGT 617
GV P S+ ++ + + DVND P S+P Y ++EN+P ++ + A D D N
Sbjct: 1115 GVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYP-EIMENSPKDVSVVQIEAFDPDSSSNDK 1173
Query: 618 VRFSLQEAETDRRSFRLDPVSGRLSTIS-SLDREEQAFYSLLVLATDLGSPPQSSMARIN 676
+ + + + F + P +G ++T S LDRE+Q + L V TD GSPP+S++AR+
Sbjct: 1174 LMYKITSG-NPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVI 1232
Query: 677 VSLLDINDNSPVFYPVQYFAHIKENEPGG-------SYITTVSATDPDLGTNGTVKYSIS 729
V +LD NDN P F Y + E E + V ATD D G N + YSI
Sbjct: 1233 VKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIE 1292
Query: 730 AG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQD 788
G + +F + ++GV+S++ E L I A D G Q + + I +
Sbjct: 1293 DGNEHGKFFIEPKTGVVSSKRFSAAGEYDI--LSIKAVDNGRPQKSSTTRLHIEWISKPK 1350
Query: 789 ---NPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVT 845
P F + ++F V E+ + + +G +S + + + IT G+ F +++ T
Sbjct: 1351 PSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGI--PLWFDITGGNYDSHFDVDKGT 1408
Query: 846 GQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVEN 905
G + A +D E++S Y L V A+ GT T T V I V D ND+ P F + V + E+
Sbjct: 1409 GTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPED 1468
Query: 906 WQAGHSIFQAKAVDPDEGVNGMVLYSLK--QNPKNL--FAINEKNGTISLLGPLDVHA-G 960
I Q AVD DE ++Y+L+ ++P +L F ++ G++ LD A
Sbjct: 1469 TAPETEILQISAVDQDE--KNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVH 1526
Query: 961 SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQA 1020
+ + ++ D VP + + V V D ND++P F SY+ + ES V S +V A
Sbjct: 1527 QHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTA 1586
Query: 1021 SDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEP 1079
DKD G N E+ Y+I GN G++F I P G + ELDR Q Y LMV A+D+ P
Sbjct: 1587 LDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPP 1646
Query: 1080 LSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF 1139
+S +V + + ++ P F S Y+ E GSFVG V+A + V Y
Sbjct: 1647 MSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQ-----SSVVYEI 1701
Query: 1140 E--MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVH 1197
+ F+++ SG I D E+L +++ + T+ L TV
Sbjct: 1702 KDGNTGDAFDINPHSGTIITQKALDFETL------PIYTLIIQGTNMA---GLSTNTTVL 1752
Query: 1198 VYMKDINDNAPKFLKDFYQATISESAANLTQVLR-------VSASDVDEGNNGLIHYSII 1250
V+++D NDNAP F++ Y ISESA+ + VL + A+D D+ +N L+ Y I+
Sbjct: 1753 VHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIV 1812
Query: 1251 KGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLN--IDILDE 1308
+ + FAIDS++G + + LDYE T + +Q D GT L + N + ++D
Sbjct: 1813 EPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDI 1872
Query: 1309 NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN 1368
ND P F K +L G V +V ATD+DS + L YSIT N FS+
Sbjct: 1873 NDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYK 1932
Query: 1369 TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKS 1428
TG++ + + +S Y+L + A D GR + SV I+V++ ++ F D++ +
Sbjct: 1933 TGALTVQNTT--QLRSRYELTVRASD-GR--FAGLTSVKINVKESKESHLKFTQ-DVYSA 1986
Query: 1429 IV-ENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTI-YTNAEIDR 1486
+V EN ++ +TA IN L Y I+ R F I G + T DR
Sbjct: 1987 VVKENSTEAETLAVITA--IGNPINEPLFYHILNPDRR---FKISRTSGVLSTTGTPFDR 2041
Query: 1487 EFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALA-ADPSAVIGS 1545
E F++ V+ ++ P +K ++V D NDN P+F++ A +G
Sbjct: 2042 EQQEAFDVVVEVTEEHKPSAVAHVVVK---VIVEDQNDNAPVFVNLPYYAVVKVDTEVGH 2098
Query: 1546 VLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLIYNLIVSATD 1605
V+ + A D D G NGE+ Y + I L+ L Y + V A D
Sbjct: 2099 VIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLGEISLKKQFELDTLNKEYLVTVVAKD 2158
Query: 1606 LGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEY 1665
G + + I + PVF +P Y + E + + V+ ++A SP G + +
Sbjct: 2159 GGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLKV---F 2215
Query: 1666 YIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAE 1725
Y ++ + FTI +TG+I A LD E Y + + A + T
Sbjct: 2216 YSIT----DGDPFSQFTINFNTGVINVIAPLDFEAHPA-YKLSIRATDSLTG--AHAEVF 2268
Query: 1726 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII---SG 1782
V+I + DINDNPPVF +T+ E G+ ++Q+ A D+D N ++Y + S
Sbjct: 2269 VDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSK 2328
Query: 1783 ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTP 1839
+ D F +D +G + R LD E+ ++++ VRA DG SSD+ + + V+D+ND+ P
Sbjct: 2329 SHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPP 2388
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFN 1899
F + +Y I E G V + A D DS ++ Y + ++ F ++ TG+
Sbjct: 2389 LFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIIT 2448
Query: 1900 LTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPV 1959
L+ L + ++ +Y L + DG + +T +V+ ++ N + P F N Y L EN P+
Sbjct: 2449 LSNLHRHALKPFYSLNLSVSDGVFRSST-QVHVTVIGGNLHSPAFLQNEYEVELAENAPL 2507
Query: 1960 GSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQ 2019
+ V+ TD D GI +TY I + + +F +++ G + L+ LDRE+ + V+
Sbjct: 2508 HTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEKLDRETPA--EKVIS 2565
Query: 2020 VHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL-TYIPENTPIDTVVFKAQATDPD 2078
V L A + V++IL D NDN P F + K I + T V K A+D D
Sbjct: 2566 VR-LMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDAD 2624
Query: 2079 SGPNSYIEYTL---LNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLS 2135
G N+ I Y + + I + G + L E +T V A D G PS
Sbjct: 2625 EGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKE 2684
Query: 2136 SSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVN 2195
S V V +L P F++ Y ++E+ GT+I + A +G V Y +V
Sbjct: 2685 SVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEH-----SGTVLYSLVK 2739
Query: 2196 GNT-----NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQA-TDRGSTPRTDTSTVSIVL 2249
GNT ++ F ID +G + + K LD E T Y ++ A + + VSI +
Sbjct: 2740 GNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQV 2799
Query: 2250 LDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFT 2309
D ND PVFE SPY + ENL R ++Q+ A D D G+N ++ Y L
Sbjct: 2800 KDANDNSPVFESSPYEAFIVENLPGGSR-VIQIRASDADSGTNGQVMYSLDQSQSVEVIE 2858
Query: 2310 LSA----SGELGVTQSLDRETKERFVLMITATDSGSP-ALTGTGTINVIVDDVNDNVPTF 2364
A +G + + LD E ++ + + + A+D G L+ T ++V V DVND+ P F
Sbjct: 2859 SFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRF 2918
Query: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADA---SKNAVIRIIGGN--SQFTIN--PSTGQI 2417
++ Y T+ ED P G + +++ +DAD+ ++ I GG+ QF + + ++
Sbjct: 2919 TAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKV 2978
Query: 2418 ITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPS 2477
LDRE +DNY L + +D SS V V V D NDN P + Y IP
Sbjct: 2979 YVKKPLDREKRDNYLLTITATDG----TFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPE 3034
Query: 2478 PTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFS 2537
LPG + ++ TDADI N+E+ Y+L G +EKF ++P G + + PL+ + +
Sbjct: 3035 DVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYH 3094
Query: 2538 VHVK--DGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTI--TGSS 2593
+ V+ DGG S +T+ VN + P+ A EN +L+T + T +
Sbjct: 3095 LLVRATDGGGRFCQASIVLTLEDVND-NAPEFSADPYAITVFENTEPGTLLTRVQATDAD 3153
Query: 2594 LRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP-PFSSY 2652
Y + F I++L+G + + +PLD E Y + ++A D G P ++
Sbjct: 3154 AGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTAT 3213
Query: 2653 EKLDITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMDKDSGPNGQLDYEIVNGN 2711
+ ++VLD+NDN P+F+ + + + E+ L ++L V A +D N ++ Y I++GN
Sbjct: 3214 GTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGN 3273
Query: 2712 MENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAP 2771
FSI+ TG + + LD E Y LT++++D G+PS S V +N+ D NDN P
Sbjct: 3274 EHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTP 3333
Query: 2772 RFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDAS--LPFTINPSTGDIV 2828
FSQ ++ + E++ L +V V D D N+ YSI+D + FTI+P G++
Sbjct: 3334 VFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVK 3393
Query: 2829 ISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELT 2885
+++ L+RE Y + V A D+G +T V I V+D+NDNAP FSR +Y + E
Sbjct: 3394 VTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENK 3453
Query: 2886 EIGSKVTQVFATDPDEGSNGQVFYF---IKSQSEYFRINATTGEIFNKQILKYQNVTGFS 2942
+G V Q+ TD D NG F+F + + F +N G + +K +
Sbjct: 3454 PVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVN-PQGVLLTSSAIKRKEK---- 3508
Query: 2943 NVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKL 3002
+ + V +D GKP L S T + I +++ + P L + F + G +
Sbjct: 3509 ----DHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVI 3564
Query: 3003 IRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAK 3062
++ A D + + S D + + TG +A + D+ Q + + V+
Sbjct: 3565 GKIHATDQDVYDTLT-----YSLDPQMDNLFSVSSTGGKLIAHKKL-DIGQ-YLLNVSVT 3617
Query: 3063 DKGNPPLSSQATVHI-TVTEE 3082
D G + TVHI VT+E
Sbjct: 3618 D-GKFTTVADITVHIRQVTQE 3637
Score = 1096 bits (2835), Expect = 0.0
Identities = 982/3553 (27%), Positives = 1625/3553 (45%), Gaps = 271/3553 (7%)
Query: 64 IQTRPGFTYRLSESHALFAINSSTGALYTTSTID--------RESLPSDVINLVVLSSAP 115
I T F Y + +FAI+ ++G + T +D E L +D + SS
Sbjct: 178 IGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGI 237
Query: 116 TYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYR 175
+ ++ V + N+ APV + V + + T D D G+NG D S
Sbjct: 238 SSMAKLTVHIEQANECAPVI---TAVTLSPSELDRDPAYAIVTVDDCDQGANG-DIASLS 293
Query: 176 IIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTP-QYQLLVEVEDKGEPKRRGYL 234
I+ G+ +FR + S E + + GG+D + P Y L ++ +DKG P + +
Sbjct: 294 IVAGDLLQQFRTVRSFPGSKE---YKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSV 350
Query: 235 QV-NVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEG 293
+V +VT P F Y+A + E A + V+ V A A + +RY +
Sbjct: 351 KVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA----YSHLRYVF--KS 404
Query: 294 TP----FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDN 349
TP F ++ TGLI++ EP+ + + L V DR + L+++L N N
Sbjct: 405 TPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDR-----KASTKVLVKVLGANSN 459
Query: 350 DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
P F T+ A+ DEN +GT V L+ D D NG ++ I N V
Sbjct: 460 PP-----EFTQTAYKAAFDENVPIGTTVMSLSAVDPDE-GENGYVTYSIANLN-----HV 508
Query: 410 QSSKVPNLSLIKVASALDRERIPS-YNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDI 468
+ + + LD E +P Y L + SD +G P V+ +++ +N++
Sbjct: 509 PFAIDHFTGAVSTSENLDYELMPRVYTLRIRASD-WGLPYRREVEVLATIT-----LNNL 562
Query: 469 NDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEH 528
ND+ P+F + + + G ++ +SA D D ++Y I +GN L +F ++ +
Sbjct: 563 NDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADE--LQLVQYQIEAGNELDFFSLNPN 620
Query: 529 SGLVTTGSS--GGLDREL--------------------------ASQIVLNISARDQGVH 560
SG+++ S GL ++ AS ++N+ + GV
Sbjct: 621 SGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVA 680
Query: 561 PKVSYAQLVVTLL--------------DVNDEKPVFSQPEGYDVSVVENAPTGTELLMLR 606
++ L L VN P F + V EN P G+ ++ +
Sbjct: 681 KMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMN 740
Query: 607 ATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGS 666
+TD D G NG + +++ D F +D +G L +S LDRE Y+L + DLG
Sbjct: 741 STDLDTGFNGKLVYAVSGGNED-SCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGI 799
Query: 667 PPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKY 726
P +++ ++V ++D NDN P F YF + E++ S I V ATD DLG NG V Y
Sbjct: 800 PQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTY 859
Query: 727 SISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSP--NQAIVTITVL 784
SI D F +++ +GV++ LDRE + + L+I A D + + +V +++
Sbjct: 860 SI-VTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLE 918
Query: 785 DTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQ-KGMFAINQ 843
D DNPP F Y V E++ G + + A DL + + D +G F +++
Sbjct: 919 DVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDK 978
Query: 844 VTGQLTTANVIDREEQSFYQLKVVASGG----TVTGDTMVNITVKDLNDN--SPHFLQAI 897
++G + +D E++ Y L V A +++ V + V D+N+N P F +
Sbjct: 979 LSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFV 1038
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
E V E+ G + A D D +G + YS++ + +F I E+ G I LD
Sbjct: 1039 EKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLD 1098
Query: 957 VHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRF 1015
+ S Y + + A+D GV LSS + + + V DVNDN+P + Y + E+ P +
Sbjct: 1099 RESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSV 1158
Query: 1016 FKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKS--ELDRELQDRYVLMVVAS 1073
+++A D DS +N ++ Y I GN F I P L + +LDRE QD ++L V +
Sbjct: 1159 VQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVT 1218
Query: 1074 DRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAG-------SFVGKVSAVD 1126
D P S V V + D NDN+P F Y E ++ + V A D
Sbjct: 1219 DNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATD 1278
Query: 1127 KDFGPNGEVRYSFE--MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI---A 1181
KD GPN E+ YS E F + +G +++ +R +A + ++ A
Sbjct: 1279 KDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSS-----------KRFSAAGEYDILSIKA 1327
Query: 1182 TDQGIPQPLKDQATVHVYMKDINDNAP-----KFLKDFYQATISES--AANLTQVLRVSA 1234
D G PQ +T ++++ I+ P F + F+ T+ ES A++ V+ V
Sbjct: 1328 VDNGRPQ---KSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEP 1384
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
+ + + I GN + F +D +G + + LD E Y+L ++A D T
Sbjct: 1385 PGIP------LWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTI 1438
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
L + I ++D ND+ P F S V + E+ + ++A D D + L Y++
Sbjct: 1439 LTQ---VFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQD--EKNKLIYTL 1493
Query: 1355 TGTNNH---GTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
+ + F + P TGS++ ++KLD E + L + +DQ P + + +V++V
Sbjct: 1494 QSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVS 1553
Query: 1412 DFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
D ND+ P F + E+ +G+ V+ VTA D D N ++ Y+ I+ GN F I
Sbjct: 1554 DTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYS-IESGNIGNSFMI 1612
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
D V G+I T E+DR ++L VKA D+ P + + +V I VT ++ P F S
Sbjct: 1613 DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSE---ITSVRIFVTIADNASPKFTS 1669
Query: 1532 QN-ALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASA 1589
+ ++ + IGS + + A + + YEI +G+T D F ++ +SG + A
Sbjct: 1670 KEYSVELSETVSIGSFVGMVTA-----HSQSSVVYEIKDGNTGDAFDINPHSGTIITQKA 1724
Query: 1590 LVPSQL-IYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNV 1648
L L IY LI+ T++ +T + + + + PVF Q +Y ++ E I + V
Sbjct: 1725 LDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVV 1784
Query: 1649 IS-------IEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQ 1700
++ I AA + + S A + Y+IV E +V F I TG I T LD E+
Sbjct: 1785 LTDRNVPLVIRAADADKDSNALLVYHIV-----EPSVHTYFAIDSSTGAIHTVLSLDYEE 1839
Query: 1701 GACL-YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKI 1759
+ + V V+ + F A V + + DIND PPVF + + ++ G K+
Sbjct: 1840 TSIFHFTVQVHDMGTPRLFAE-YAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKV 1898
Query: 1760 MQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADD 1818
+ + A DAD A + + Y+I G + F +D ++G L T + + RS+Y L VRA D
Sbjct: 1899 ITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGAL--TVQNTTQLRSRYELTVRASD 1956
Query: 1819 GLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITY 1878
G + + I V + + KF++ VYS + E++ +A I A + +N + Y
Sbjct: 1957 GRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNP--INEPLFY 2014
Query: 1879 -IVNEDDEDGIFFLNPITGVFNLTRL-LDYEVQQYYILTVRAEDGGGQFTTIRVYFNIL- 1935
I+N D F ++ +GV + T D E Q+ + + V + V ++
Sbjct: 2015 HILNPDRR---FKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIV 2071
Query: 1936 -DVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTV 1994
D NDN P+F Y + + VG + D D G N ++ Y + F +
Sbjct: 2072 EDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHE--HFQI 2129
Query: 1995 DKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSP 2054
G + + K + ++ + LV V PA +A+V + + +N P F P
Sbjct: 2130 GPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPA----FSAEVIVPITVMNKAMPVFEKP 2185
Query: 2055 KLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELD 2113
+ I E+ + + V QA P+ G + T +P ++F+I G + + LD
Sbjct: 2186 FYSAEIAESIQVHSPVVHVQANSPE-GLKVFYSITDGDPF-SQFTINFNTGVINVIAPLD 2243
Query: 2114 REEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDI 2173
E Y L++ ATD + V ++V DINDN P+FAQ Y V ++E ++ GT +
Sbjct: 2244 FEAHPAYKLSIRATD-SLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSV 2302
Query: 2174 IQVFAADGDEGTNGQVRYGIV--NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQA 2231
+QV A D D N + Y + + ++ F +DS TG I++ + LD E++ + + V+A
Sbjct: 2303 VQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRA 2362
Query: 2232 TDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGS 2291
D G + V++ + D+ND P+FE Y + E+ + V A D D
Sbjct: 2363 VDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEH-APHGHFVTCVKAYDADSSD 2421
Query: 2292 NSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTIN 2351
KL Y + GN+ F + ++ + +L R + F + + G + ++
Sbjct: 2422 IDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDG--VFRSSTQVH 2479
Query: 2352 VIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADAS--KNAVIRIIG--GNSQ 2407
V V N + P F Y + E+AP T V+ V +D D+ + I+ +
Sbjct: 2480 VTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDR 2539
Query: 2408 FTINPSTGQIITSALLDRETKDNYTLVV--VCSDAGSPEPLSSSTSVLVTVTDVNDNPPR 2465
F IN GQI T LDRET + V + DAG + +V V +TD NDN P+
Sbjct: 2540 FYIN-ERGQIFTLEKLDRETPAEKVISVRLMAKDAGGK---VAFCTVNVILTDDNDNAPQ 2595
Query: 2466 FQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRN---SEKFHIDPLRGAI 2522
F+ Y +I S G+ V V +DAD G N+++ Y++ + E I+ L G I
Sbjct: 2596 FRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVI 2655
Query: 2523 MAAGPLNGASE--VTFSVHVKDGGSFPKTDSTTVTVRFV-NKADFPKVRAKEQTFMFPEN 2579
L G TF V D GS K V V+ + + PK TF E+
Sbjct: 2656 TTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSED 2715
Query: 2580 QPVSSLVTTITGSSLRGEPMSYYIASGNL-----GNTFQIDQLTGQVSISQPLDFEKIQK 2634
P+ + + I + Y + GN +F ID+ +G++ + + LD E +
Sbjct: 2716 VPIGTEIDLIRAE--HSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKW 2773
Query: 2635 YVVWIEAR--DGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENL-SPRKILTVS 2691
Y I AR +S + + I V D NDN+P+F+ P+ + I+ENL +++ +
Sbjct: 2774 YQFSILARCTQDDHEMVASVD-VSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIR 2832
Query: 2692 AMDKDSGPNGQLDYEIVNG---NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDK 2748
A D DSG NGQ+ Y + + SF+IN TG I +++ LD EK +Y + + +SD
Sbjct: 2833 ASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDH 2892
Query: 2749 GSPSQSTSVKVM-INILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDI-GINA 2805
G Q +S ++ + + D ND+ PRF ++I+ V E+ P G + ++T+D D IN
Sbjct: 2893 GEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINR 2952
Query: 2806 ISRYSIM--DASLPFTINPSTGD--IVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIF 2861
Y I D F + + + + +PL+RE D Y + ++A D ++ V +
Sbjct: 2953 QVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVK 3012
Query: 2862 VTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY-FIKSQSEYFRI 2920
V D NDN+P +T Y PE G + Q+ ATD D SN ++ Y + S +E F++
Sbjct: 3013 VLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKL 3072
Query: 2921 NATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
N TGE+ + T + +V ++D G + ++ + + D NDNA
Sbjct: 3073 NPDTGEL--------KTSTPLDREEQAVYHLLVRATDGG--GRFCQASIVLTLEDVNDNA 3122
Query: 2981 PQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGW 3040
P+F Y V +N + GT L RV A D D GLN ++ Y + D+ G+F ++ +G
Sbjct: 3123 PEFSADPYAITVFENTEPGTLLTRVQA-TDADAGLNRKILYSLI-DSADGQFSINELSGI 3180
Query: 3041 ISVASSLISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
I + L +L + +++ A D+G P L++ TV ++V + N + P F AT+
Sbjct: 3181 IQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVS 3240
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
E +G+ V V A RD N I YSI SGNE G F+I+S TG + + + LDYE +
Sbjct: 3241 EDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHE 3300
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+ +T+ A DGG + + +V VNV D+NDN+PVF D Y + E+A +VI + A
Sbjct: 3301 YYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMAD 3360
Query: 3220 DADSGTNAVIAYT-VQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEER 3278
DAD +N+ I Y+ + + F IDP G + LD ET Y LTV+A + R
Sbjct: 3361 DADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPR 3420
Query: 3279 CSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHY--L 3336
+ TVNI + N+ P F Y I E P G V ++ +D D +G + +
Sbjct: 3421 VNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTI 3480
Query: 3337 IFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVL 3396
+ GN +K F++N + G + S + R++++ L+V + G + + + + + V
Sbjct: 3481 VTGND-EKAFEVNPQ-GVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEE 3538
Query: 3397 DANDPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSIN 3456
P I L I+ E G + + A D D + +Y + +N FS++
Sbjct: 3539 SIYPPAILPLEIFITSSGEEYSGGV-IGKIHATDQD---VYDTLTYSLDPQMDN-LFSVS 3593
Query: 3457 PQTGQITVTAELD 3469
G++ +LD
Sbjct: 3594 STGGKLIAHKKLD 3606
Score = 1095 bits (2833), Expect = 0.0
Identities = 1047/3645 (28%), Positives = 1662/3645 (45%), Gaps = 297/3645 (8%)
Query: 119 TEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIR 178
T+VRV V D ND P+F S V+ E+++ + +ATD+DIG+NG + S++
Sbjct: 133 TKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFK--- 189
Query: 179 GNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDK-----GEPKRRGY 233
+ F + T SG +V G LD T Y++ + D+ G
Sbjct: 190 -DRTDMFAIHPT---SGV-----IVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSM 240
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEG 293
++ V ++ N+ PV + P + + V D D+G N DI G
Sbjct: 241 AKLTVHIEQANECAPVITAVTLS---PSELDRDPAYAIVTVDDCDQGANGDIASLSIVAG 297
Query: 294 TPFQM--------DPETGLITVREPLDFEARR-QYSLTVQAMDRGVPSLTGRAEALIQLL 344
Q + + +D+++ Y+LT+QA D+G P + +
Sbjct: 298 DLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTS 357
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ 404
PV F A + E A T V ++ A S ++ +
Sbjct: 358 PQFKAGPV----KFEKDVYRAEISEFAPPNTPVVMVKAIPAYS-----HLRYVFKSTPGK 408
Query: 405 RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIF 464
F + N LI + + R++ + L V+ SD R + +++
Sbjct: 409 AKFSLNY----NTGLISILEPVKRQQAAHFELEVTTSD------------RKASTKVLVK 452
Query: 465 VNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFH 524
V N +PP F+Q Y+ E P G+ V +SA D D G N + YSI + N + F
Sbjct: 453 VLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVP-FA 511
Query: 525 ISEHSGLVTTGSSGGLDRELASQI-VLNISARDQGVHPKVSYAQL-VVTLLDVNDEKPVF 582
I +G V+T S LD EL ++ L I A D G+ + L +TL ++ND P+F
Sbjct: 512 IDHFTGAVST--SENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLF 569
Query: 583 SQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLS 642
+ + ++ + G ++ + A D D + V++ + EA + F L+P SG LS
Sbjct: 570 -EKINCEGTIPRDLGVGEQITTVSAIDAD--ELQLVQYQI-EAGNELDFFSLNPNSGVLS 625
Query: 643 TISSLD---REEQAFYSLLVLATD---------LGSPPQSSMARINV------------- 677
SL + +F+SL + ATD + +S +N+
Sbjct: 626 LKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAE 685
Query: 678 SLLDIN-------------DNSPVFYPVQYF-------AHIKENEPGGSYITTVSATDPD 717
LL N D+ V + F +KEN+P GS + +++TD D
Sbjct: 686 KLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLD 745
Query: 718 LGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
G NG + Y++S G+ S F ++ ++G++ LDRE Y L I D G Q
Sbjct: 746 TGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAW 805
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL--NSNISYLITTGD 834
++ + V+D DNPP F Q +Y V E+ + + V A+ DL N +++Y I T
Sbjct: 806 RLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVT-- 863
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGT-----VTGDTMVNITVKDLNDN 889
F+I+ VTG + A +DRE Q + LK+ A + +V ++++D+NDN
Sbjct: 864 DTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDN 923
Query: 890 SPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTI 949
P F+ V V E+ G I +A DPD G +G V YSL + + F +++ +G +
Sbjct: 924 PPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAV 983
Query: 950 SLLGPLDVHAGS-YQIEILASDMGVP-QLSSSVILTVYVHDVNDN--SPVFDQLSYEVTL 1005
++ LD Y + + A D G P LSS+ + V V DVN+N PVF + T+
Sbjct: 984 RIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTV 1043
Query: 1006 SESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQD 1064
E PV S V A D+D+ +GEI Y+I +G+ F I + G + LDRE
Sbjct: 1044 KEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTS 1103
Query: 1065 RYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSA 1124
Y L V A+D+ V PLS+ + + + +EDVNDN P + Y E V ++ A
Sbjct: 1104 HYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEA 1163
Query: 1125 VDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNT-HQFDRESLMRRRGTAVFSFTVIA 1181
D D N ++ Y P F +H +G IT T + DRE ++ + TV
Sbjct: 1164 FDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDRE----QQDEHILEVTV-- 1217
Query: 1182 TDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESA-------ANLTQVLRVSA 1234
TD G P P A V V + D NDN P+FL+ FY+ + E A + V A
Sbjct: 1218 TDNGSP-PKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIA 1276
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLV-IQAVDSGTI 1293
+D DEG N I YSI GNE +F I+ +G ++ + A Y ++ I+AVD+G
Sbjct: 1277 TDKDEGPNAEISYSIEDGNEHGKFFIEPKTG---VVSSKRFSAAGEYDILSIKAVDNGRP 1333
Query: 1294 PLNSTCTLNIDILDE---NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADL 1350
+ST L+I+ + + + SF +S V+E+ + ++ + S L
Sbjct: 1334 QKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVI----SVEPPGIPL 1389
Query: 1351 YYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHV 1410
++ ITG N F + TG+I +AK LD E +S Y L + A D + V I V
Sbjct: 1390 WFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATD---GTTTILTQVFIKV 1446
Query: 1411 RDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRG---- 1466
D ND+ P F I E+ T ++ ++A D D +L YT+ Q R
Sbjct: 1447 IDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTL--QSSRDPLSL 1502
Query: 1467 NHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNV 1526
F +D G++YT+ ++D E + LTV DQ VP++ R +A + + V+D ND+
Sbjct: 1503 KKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVK-RNFA--RIVVNVSDTNDHA 1559
Query: 1527 PMFISQNALA-ADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDL 1584
P F + + SA +GSV+ + A D D+G N E+ Y I +G+ ++F++D G +
Sbjct: 1560 PWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSI 1619
Query: 1585 RVASALVPS-QLIYNLIVSATDLGPERRKSTTELTIILQGLD--GPVFTQPKYITILKEG 1641
+ A L S Q Y+L+V ATD G T + I + D P FT +Y L E
Sbjct: 1620 KTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSET 1679
Query: 1642 EPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQG 1701
IG+ V + A S++ V Y I ++ G F I H+G I T LD E
Sbjct: 1680 VSIGSFVGMVTA----HSQSSVVYEI-----KDGNTGDAFDINPHSGTIITQKALDFETL 1730
Query: 1702 ACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQ 1761
L+ I+ + + V + LQD NDN PVF + E+ S ++
Sbjct: 1731 PIYTLI----IQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLT 1786
Query: 1762 -------LTAMDADEGANALVTYTIIS-GADDSFRIDPESGDLIATRRLDRERRSKYSLL 1813
+ A DAD+ +NAL+ Y I+ F ID +G + LD E S +
Sbjct: 1787 DRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFT 1846
Query: 1814 VRADD---GLQSSDMRINITVS--DVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD 1868
V+ D ++ N+TV D+ND P F++P+Y + T G V + ATD
Sbjct: 1847 VQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDA 1906
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-GQFTT 1927
DS ++ Y + E + F ++ TG LT +++ Y LTVRA DG T+
Sbjct: 1907 DSSAFSQLIYSITEGNIGEKFSMDYKTGA--LTVQNTTQLRSRYELTVRASDGRFAGLTS 1964
Query: 1928 IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGD 1987
+++ N+ + ++ F+ + YS + EN T+ V +T + IN L Y I + D
Sbjct: 1965 VKI--NVKESKESHLKFTQDVYSAVVKENSTEAETLAV--ITAIGNPINEPLFYHILNPD 2020
Query: 1988 SLGQFTVDK-NGVLKVL-KALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
+F + + +GVL DRE Q +++VV+V + + A + V +I+ D N
Sbjct: 2021 R--RFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSA---VAHVVVKVIVEDQN 2075
Query: 2046 DNPPTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDG 2104
DN P F++ P + +T + V+ A D DSG N + Y L F IG + G
Sbjct: 2076 DNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHY-YLKEHHEHFQIGPL-G 2133
Query: 2105 EVRLTGELDREEVS-NYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEI 2163
E+ L + + + ++ Y +TVVA D G P+ S+ EV+V + +N P+F + Y EI
Sbjct: 2134 EISLKKQFELDTLNKEYLVTVVAKDGGNPAFSA--EVIVPITVMNKAMPVFEKPFYSAEI 2191
Query: 2164 NENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTP 2223
E+ + ++ V A+ EG +V Y I +G+ +F I+ TG I V PLD E P
Sbjct: 2192 AESIQVHSPVVHV-QANSPEGL--KVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHP 2248
Query: 2224 TYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV 2283
Y L+++ATD + + V I++ DIND PVF Y+V + E + +++QV
Sbjct: 2249 AYKLSIRATDSLTGAHAEV-FVDIIVDDINDNPPVFAQQSYAVTLSE-ASVIGTSVVQVR 2306
Query: 2284 ARDDDRGSNSKLSYVLFGG---NEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
A D D N +SY +FG + D+ S++G + + ++LD E + + + A D G
Sbjct: 2307 ATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGG 2366
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
P L+ + V V D+NDN P F + Y I E AP G V V A DAD+S ++
Sbjct: 2367 MPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQ 2426
Query: 2401 --IIGGN--SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTV 2456
I+ GN F I+ +TG I S L K Y+L + SD SST V VTV
Sbjct: 2427 YSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDG----VFRSSTQVHVTV 2482
Query: 2457 TDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHI 2515
N + P F + Y + + V V TD D G + Y + + ++F+I
Sbjct: 2483 IGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYI 2542
Query: 2516 DPLRGAIMAAGPLN--GASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKAD-FPKVRAK 2570
+ RG I L+ +E SV + KD G K TV V + D P+ RA
Sbjct: 2543 NE-RGQIFTLEKLDRETPAEKVISVRLMAKDAGG--KVAFCTVNVILTDDNDNAPQFRAT 2599
Query: 2571 EQTFMFPENQPVSSLVTTITGSSL---RGEPMSYYIA--SGNLGNTFQIDQLTGQVSISQ 2625
+ + + V + S ++Y I S ++ +I++L+G ++ +
Sbjct: 2600 KYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKE 2659
Query: 2626 PLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR 2685
L + + + ++ A D G P S + + +L P F E + + E++
Sbjct: 2660 SLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIG 2719
Query: 2686 KILTVSAMDKDSGPNGQLDYEIVNG-----NMENSFSINHATGEIRSVRPLDREKVSHYV 2740
+ + + +G + Y +V G N + SF I+ +G ++ + LD E Y
Sbjct: 2720 TEIDLIRAEH----SGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQ 2775
Query: 2741 LTIKS-SDKGSPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSD 2798
+I + + SV V I + D NDN+P F S + A + EN P G V ++ SD
Sbjct: 2776 FSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASD 2835
Query: 2799 EDIGINAISRYSI-----MDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWT 2853
D G N YS+ ++ F IN TG I + L+ E D Y+I+V A D G
Sbjct: 2836 ADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEK 2895
Query: 2854 VSTD----VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPD-EGSNGQVF 2908
+ V + VTD+ND+ PRF+ Y E G + + TD D E N QV
Sbjct: 2896 IQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVT 2955
Query: 2909 YFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETT 2968
YFI + T + K +K + + +T++D + S+
Sbjct: 2956 YFITGGDPLGQFAVETIQNEWKVYVK----KPLDREKRDNYLLTITATD---GTFSSKAI 3008
Query: 2969 VTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNH 3028
V + ++D+NDN+P K+ Y + ++V G KLI + D D N+E+ Y +
Sbjct: 3009 VEVKVLDANDNSPVCEKTLYSDTIPEDVLPG-KLIMQISATDADIRSNAEITYTLLGSG- 3066
Query: 3029 LGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPE 3088
KFKL+ DTG + ++ L + + + V A D G QA++ +T+ + N + PE
Sbjct: 3067 AEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGG--RFCQASIVLTLEDVNDNAPE 3124
Query: 3089 FSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTL 3148
FS + T+ E+ G+++ V A D DA +N I YS+ + +G F+IN +GI+ L
Sbjct: 3125 FSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLID-SADGQFSINELSGIIQL 3183
Query: 3149 AKALDYELCQKHEMTISAIDGGWVAR-TGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENA 3207
K LD EL + +++ A+D G R T +V V+V+D+NDN PVF +Y TV E+
Sbjct: 3184 EKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDI 3243
Query: 3208 PSGTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQGFLDFETKQSYHL 3266
GT V+ + A D NA I Y++ S ++ F ID TG + LD+E+ Y+L
Sbjct: 3244 LVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYL 3303
Query: 3267 TVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRD 3326
TV+A + ATVN+ + N+ P F Y ISE A V V A D D
Sbjct: 3304 TVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDAD 3363
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADI 3386
++ +HY I ++ F I+ G++ V+ +LDRE +L V A + GS +
Sbjct: 3364 GPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGS--PPRV 3421
Query: 3387 DEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIG 3445
+ TVN+ V D ND P+F+ YSV I E P+G V + D DS + F + I
Sbjct: 3422 NTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIV 3481
Query: 3446 SGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDIND 3505
+GN+ AF +NPQ G + ++ + R+ Y L V D+G P + + + + + +
Sbjct: 3482 TGNDEKAFEVNPQ-GVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESI 3540
Query: 3506 NGPMLTVSEGEVMEN--KRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSL-ST 3562
P + E + + + G ++ + +TD D+ TY L + FS+ ST
Sbjct: 3541 YPPAILPLEIFITSSGEEYSGGVIGKIHATDQDV---YDTLTYSL--DPQMDNLFSVSST 3595
Query: 3563 AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQ 3607
G L +++D I + L+V D ++ TVHI + Q
Sbjct: 3596 GGKLIAHKKLD---IGQYLLNVSVTDGKFTTVADI-TVHIRQVTQ 3636
Score = 1015 bits (2624), Expect = 0.0
Identities = 876/3028 (28%), Positives = 1412/3028 (46%), Gaps = 221/3028 (7%)
Query: 50 QVLEEQPPGTLV---GTIQTRPGFTYRL------SESHALFAINSSTGALYTTSTIDRES 100
QV E QP G+ V + GF +L + F I+ TG L S +DRE+
Sbjct: 725 QVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRET 784
Query: 101 LPSDVINLVVLSSAPTYPTEVRVL---VRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILD 157
+N+ V R+L V D NDN P F S V ED ++I
Sbjct: 785 TDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQV 844
Query: 158 TATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQ 217
ATD D+G NG H +Y I+ + F +D LDRE+ ++
Sbjct: 845 EATDKDLGPNG--HVTYSIV--TDTDTFSIDSVTGVVNIAR--------PLDRELQHEHS 892
Query: 218 LLVEVEDKG--EPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAA 275
L +E D+ EP+ + V V+++D+NDNPP F +Y+ V ED G+ ++ + A
Sbjct: 893 LKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAH 952
Query: 276 DADEGTNADIRYRLQDEGT-PFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVP-SL 333
D D G + +RY L D G F +D +G + + + LDFE ++ Y+LTV+A D+G P SL
Sbjct: 953 DPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSL 1012
Query: 334 TGRAEALIQLLDVNDN--DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAAN 391
+ ++++DVN+N PV F + +V E+A VG++V ++ D D+ +
Sbjct: 1013 SSTCYVEVEVVDVNENLHPPV-----FSSFVEKGTVKEDAPVGSLVMTVSAHDEDA-RRD 1066
Query: 392 GNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAA 451
G I I G+ F++ +I+ + LDRE Y LTV +D
Sbjct: 1067 GEIRYSIRDGSGVGVFKIGE----ETGVIETSDRLDRESTSHYWLTVFATDQ-------G 1115
Query: 452 VQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLR 511
V SS + I V D+ND+ P S+ VY + E +P V I A D DS N L
Sbjct: 1116 VVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLM 1175
Query: 512 YSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVT 571
Y I SGN G+F I +GL+TT +S LDRE + +L ++ D G PK + A+++V
Sbjct: 1176 YKITSGNPQGFFSIHPKTGLITT-TSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVK 1234
Query: 572 LLDVNDEKPVFSQPEGYDVSVVENAPTGTE-------LLMLRATDGDLGDNGTVRFSLQE 624
+LD ND KP F Q + Y + + E E L + ATD D G N + +S+++
Sbjct: 1235 ILDENDNKPQFLQ-KFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIED 1293
Query: 625 AETDRRSFRLDPVSGRLSTISSLDREEQAFYSLL-VLATDLGSPPQSSMARINVSLLDIN 683
+ F ++P +G +SS Y +L + A D G P +SS R+++ +
Sbjct: 1294 G-NEHGKFFIEPKTG---VVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKP 1349
Query: 684 DNS--PVFYPVQYFAH-IKENEPGGSYITTVSATDPDLGTNGTVKYSISAGD-RSRFQVN 739
S P+ + +F + E++P I +S P + + + I+ G+ S F V+
Sbjct: 1350 KPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGI----PLWFDITGGNYDSHFDVD 1405
Query: 740 AQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYS 799
+G I LD E+K+ Y L + ATDG + V I V+DT D+ P FS Y
Sbjct: 1406 KGTGTIIVAKPLDAEQKSNYNLTVEATDG---TTTILTQVFIKVIDTNDHRPQFSTSKYE 1462
Query: 800 FVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQK---GMFAINQVTGQLTTANVIDR 856
V+ E+ A + +SA D + + Y + + F ++ TG L T+ +D
Sbjct: 1463 VVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDH 1522
Query: 857 EEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIF 913
E + L V+ V + + V D ND++P F + V E+ G +
Sbjct: 1523 EAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVL 1582
Query: 914 QAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD-VHAGSYQIEILASDM 971
Q A+D D+G N VLYS++ N N F I+ G+I LD + Y + + A+D
Sbjct: 1583 QVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDK 1642
Query: 972 GVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEI 1031
G P +S + ++V ++ SP F Y V LSE+ + S V A + S +
Sbjct: 1643 GSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQSS-----V 1697
Query: 1032 AYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVIL 1090
Y I +GNTGDAF I P G + + LD E Y L++ ++ A LS V V L
Sbjct: 1698 VYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMA--GLSTNTTVLVHL 1755
Query: 1091 EDVNDNRPLFNSTNYTFYFEEEQRAGSFVGK-------VSAVDKDFGPNGEVRYSFEMVQ 1143
+D NDN P+F YT E S V + A D D N + Y +V+
Sbjct: 1756 QDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVY--HIVE 1813
Query: 1144 PD----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD-QATVHV 1198
P F + + +G I D E T++F FTV D G P+ + A V V
Sbjct: 1814 PSVHTYFAIDSSTGAIHTVLSLDYEE------TSIFHFTVQVHDMGTPRLFAEYAANVTV 1867
Query: 1199 YMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQF 1258
++ DIND P F K Y+A++ +V+ V+A+D D + YSI +GN +F
Sbjct: 1868 HVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKF 1927
Query: 1259 AIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKS 1318
++D +G +T+ + Y L ++A D L S + I++ + ++ F +
Sbjct: 1928 SMDYKTGALTVQNTTQLRS--RYELTVRASDGRFAGLTS---VKINVKESKESHLKFTQD 1982
Query: 1319 TLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSI-FLAKK 1377
V EN E ++ +TA + N L+Y I N F IS +G +
Sbjct: 1983 VYSAVVKENSTEAETLAVITAIGNPI--NEPLFYHI--LNPDRRFKISRTSGVLSTTGTP 2038
Query: 1378 LDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGT 1437
D E Q + + + ++ +P + + V + V D NDN P F + + + +G
Sbjct: 2039 FDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGH 2098
Query: 1438 SVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANL-FELTV 1496
+ VTA D D+ NG++ Y + + HF I + G I + + + N + +TV
Sbjct: 2099 VIRYVTAVDRDSGRNGEVHYYLKE---HHEHFQIGPL-GEISLKKQFELDTLNKEYLVTV 2154
Query: 1497 KANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAV-IGSVLTTIMAADP 1555
A D P + V + +T +N +P+F A ++ + S + + A P
Sbjct: 2155 VAKDGGNPAFS-----AEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSP 2209
Query: 1556 DEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATD-LGPERRK 1612
EG ++ Y I +GD F ++ +G + V + L + Y L + ATD L +
Sbjct: 2210 -EGL--KVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAE 2266
Query: 1613 STTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA-SPRGSEAPVEYYIVSVR 1671
++ + + PVF Q Y L E IGT+V+ + A S + Y +
Sbjct: 2267 VFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNH 2326
Query: 1672 CEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQ 1731
+ F + TG+I LD EQ + + V A++ T ++V +T+
Sbjct: 2327 SKSHD---HFHVDSSTGLISLLRTLDYEQSR-QHTIFVRAVDGGMP---TLSSDVIVTVD 2379
Query: 1732 --DINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDS-FR 1788
D+NDNPP+F + + + E+ G + + A DAD + Y+I+SG D F
Sbjct: 2380 VTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFV 2439
Query: 1789 IDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSF 1848
ID +G + + + YSL + DG+ S ++++TV N H+P F + Y
Sbjct: 2440 IDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEV 2499
Query: 1849 DIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV 1908
++ E+ +LV + TD DSG+ G +TY + D F++N +F L + LD E
Sbjct: 2500 ELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEK-LDRET 2558
Query: 1909 QQYYILTVR--AEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVF 1966
+++VR A+D GG+ V + D NDN P F Y ++ + G++V+
Sbjct: 2559 PAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKV 2618
Query: 1967 NVTDADDGINSQLTYSI-ASGDSLGQ-FTVDK-NGVLKVLKALDRESQSFYNLVVQVHDL 2023
+DAD+G N+ +TY+I A +S+ + ++K +GV+ ++L F+ V+ D
Sbjct: 2619 LASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVD- 2677
Query: 2024 PQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT------YIPENTPIDTVVFKAQATDP 2077
S ++ S++L+ V PP PK + + E+ PI T + +A
Sbjct: 2678 -------NGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRA--E 2728
Query: 2078 DSGPNSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNYTLTVVA-TDKGQPS 2133
SG Y P N+ F I G ++L LD E Y +++A +
Sbjct: 2729 HSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHE 2788
Query: 2134 LSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGI 2193
+ +S +V + V D NDN+P+F + Y+ I EN G+ +IQ+ A+D D GTNGQV Y +
Sbjct: 2789 MVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSL 2848
Query: 2194 VNGNT---NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPR-TDTSTVSIVL 2249
+ + F I+ TG IT K LD EK Y + V A+D G + + T+ V + +
Sbjct: 2849 DQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTV 2908
Query: 2250 LDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAF- 2308
D+ND P F Y V E+ + D N +++Y + GG+ F
Sbjct: 2909 TDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFA 2968
Query: 2309 --TLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFAS 2366
T+ ++ V + LDRE ++ ++L ITATD + + V V D NDN P
Sbjct: 2969 VETIQNEWKVYVKKPLDREKRDNYLLTITATDG---TFSSKAIVEVKVLDANDNSPVCEK 3025
Query: 2367 KAYFTTIPEDAPTGTDVLLVNASDADASKNAVI--RIIG-GNSQFTINPSTGQIITSALL 2423
Y TIPED G ++ ++A+DAD NA I ++G G +F +NP TG++ TS L
Sbjct: 3026 TLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPL 3085
Query: 2424 DRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGS 2483
DRE + Y L+V +D G S+++T+ DVNDN P F PY + T PG+
Sbjct: 3086 DREEQAVYHLLVRATDGGG---RFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGT 3142
Query: 2484 FVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK-- 2541
+ V TDAD G N ++ YSL +F I+ L G I PL+ + +++ +K
Sbjct: 3143 LLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAV 3202
Query: 2542 DGGSFPK--TDSTTVTVRFVNKADFPKV-RAKEQTFMFPENQPVSSLVTTITGSSLRGE- 2597
D G P+ T + TV V ++ D P V +E E+ V + V + +S E
Sbjct: 3203 DQG-LPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEA 3261
Query: 2598 --PMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKL 2655
++Y I SGN F ID TG V I + LD+E +Y + +EA DGG P S +
Sbjct: 3262 NAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATV 3321
Query: 2656 DITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMDKDSGPNGQLDYEIVNGNMEN 2714
++ V D+NDN P+F +D + + I E+ + + ++TV A D D N + Y I++GN +
Sbjct: 3322 NVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGS 3381
Query: 2715 SFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFS 2774
SF+I+ GE++ + LDRE +S Y LT+++SD GSP + + V I++ D NDNAP FS
Sbjct: 3382 SFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFS 3441
Query: 2775 Q-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM---DASLPFTINPSTGDIVIS 2830
+ +S + EN P+G++V ++ +DED N + + + F +NP G ++ S
Sbjct: 3442 RGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQ-GVLLTS 3500
Query: 2831 RPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEI 2887
+ R++ D Y ++V D+G + T + I V + + P ++
Sbjct: 3501 SAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYS 3560
Query: 2888 GSKVTQVFATDPDEGSNGQVFYFIKSQSE-YFRINATTGEIFNKQILKYQNVTGFSNVNI 2946
G + ++ ATD D + Y + Q + F +++T G++ ++I
Sbjct: 3561 GGVIGKIHATDQDVYDT--LTYSLDPQMDNLFSVSSTGGKLI-----------AHKKLDI 3607
Query: 2947 NRHSFIVTSSDRGKPSLISETTVTINIV 2974
++ V+ +D GK + +++ TV I V
Sbjct: 3608 GQYLLNVSVTD-GKFTTVADITVHIRQV 3634
Score = 876 bits (2264), Expect = 0.0
Identities = 792/2756 (28%), Positives = 1277/2756 (46%), Gaps = 241/2756 (8%)
Query: 996 FDQLSYEVTLSESEPVNSRF-FKVQASDKDSGANGEIAYTIAEGNTGDAF-------GIF 1047
F L Y VT+ E+ + V+ + E+ Y I G++ + F G F
Sbjct: 34 FTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYILGDF 93
Query: 1048 PDGQLYIKSE----LDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNST 1103
++ K L+RE++D Y L+V A ++ + A V V + D ND RPLF+ T
Sbjct: 94 CFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTN-VEARTKVRVQVLDTNDLRPLFSPT 152
Query: 1104 NYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDR 1163
+Y+ E + + +VSA D D G NGE YSF+ F +H SG I T + D
Sbjct: 153 SYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDY 212
Query: 1164 ESLMRRRGTAVFSFTVIATDQGI----PQPLKDQATVHVYMKDINDNAPKFLKDFYQATI 1219
T ++ ++A D+G+ + A + V+++ N+ AP T+
Sbjct: 213 LE------TKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVIT----AVTL 262
Query: 1220 SESAANLTQVLR-VSASDVDEGNNG-LIHYSIIKGNEERQFAI-----DSTSGQVTLIGK 1272
S S + V+ D D+G NG + SI+ G+ +QF S +V IG
Sbjct: 263 SPSELDRDPAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGG 322
Query: 1273 LDYEATP-AYSLVIQAVDSGTIP-LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRI 1330
+D+++ P Y+L +QA D GT P +S +++ F K ++ E
Sbjct: 323 IDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPP 382
Query: 1331 GELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNI 1390
V V A + S L Y T FS++ NTG I + + + + + ++L +
Sbjct: 383 NTPVVMVKAIPAYS----HLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEV 438
Query: 1391 TAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDAD 1450
T D R ++ V++ V N NPP F + EN+PIGT+V+S++A DPD
Sbjct: 439 TTSD-----RKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEG 493
Query: 1451 INGQLSYTIIQQMPRGNH--FTIDEVKGTIYTNAEIDRE-FANLFELTVKANDQAVPIET 1507
NG ++Y+I NH F ID G + T+ +D E ++ L ++A+D +P
Sbjct: 494 ENGYVTYSIANL----NHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPY-- 547
Query: 1508 RRYALKNVTILVTDLNDNVPMFISQNALAADPSAV-IGSVLTTIMAADPDEGANGEIEYE 1566
RR TI + +LNDN P+F N P + +G +TT+ A D DE ++Y+
Sbjct: 548 RREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADE--LQLVQYQ 605
Query: 1567 IING-DTDTFIVDRYSGDLRVASALV----------------------PSQLIYNLIVSA 1603
I G + D F ++ SG L + +L+ + L N+ V+A
Sbjct: 606 IEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAA 665
Query: 1604 TDLGPERRKSTTELTIIL------------QGLDGPVF---------------TQPKYIT 1636
+ + T + +L QG +F T P I
Sbjct: 666 SHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQ 725
Query: 1637 ILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAIL 1696
+ KE +P+G++VI + + Y VS E+ F I TG+++ + L
Sbjct: 726 V-KENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDS----CFMIDMETGMLKILSPL 780
Query: 1697 DREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDG 1756
DRE Y +++ + R + + + D NDNPP F + + V E+
Sbjct: 781 DRET-TDKYTLNITVYDLGIPQKAAWRL-LHVVVVDANDNPPEFLQESYFVEVSEDKEVH 838
Query: 1757 SKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA 1816
S+I+Q+ A D D G N VTY+I++ D+F ID +G + R LDRE + ++SL + A
Sbjct: 839 SEIIQVEATDKDLGPNGHVTYSIVTDT-DTFSIDSVTGVVNIARPLDRELQHEHSLKIEA 897
Query: 1817 DDGLQS-----SDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSG 1871
D + S + + +++ DVND+ P F P Y + ED G+++ + A D D G
Sbjct: 898 RDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLG 957
Query: 1872 VNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG---GQFTTI 1928
+G++ Y + D +G F ++ ++G + + LD+E +Q Y LTVRA+D G +T
Sbjct: 958 QSGQVRYSL-LDHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTC 1016
Query: 1929 RVYFNILDVNDN--PPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
V ++DVN+N PP+FS ++ E+ PVGS V+ + D D + ++ YSI G
Sbjct: 1017 YVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDG 1076
Query: 1987 DSLGQFTV-DKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
+G F + ++ GV++ LDRES S Y L V D +P S F ++ I + DVN
Sbjct: 1077 SGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSF---IEIYIEVEDVN 1133
Query: 2046 DNPPTFLSPKLTYIP---ENTPIDTVVFKAQATDPDSGPNSYIEYTLL--NPLGNKFSIG 2100
DN P P Y P EN+P D V + +A DPDS N + Y + NP G FSI
Sbjct: 1134 DNAPQTSEP--VYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQG-FFSIH 1190
Query: 2101 TIDGEVRLTG-ELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 2159
G + T +LDRE+ + L V TD G P S+ V+V +LD NDN P F Q Y
Sbjct: 1191 PKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFY 1250
Query: 2160 KVEI-------NENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAIT 2212
K+ + E + V A D DEG N ++ Y I +GN + +F I+ TG ++
Sbjct: 1251 KIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVS 1310
Query: 2213 VAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI--VLLDINDFVPV-FELSPYSVNVP 2269
+ + L+++A D G ++ T+ + I + P+ FE S ++ V
Sbjct: 1311 SKRFSAAGEYDI--LSIKAVDNGRPQKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVM 1368
Query: 2270 ENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRETKE 2328
E+ + ++ L + + GGN D+ F + +G + V + LD E K
Sbjct: 1369 ES-----DPVAHMIGVISVEPPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKS 1423
Query: 2329 RFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNA 2388
+ L + ATD + LT + + V D ND+ P F++ Y IPED T++L ++A
Sbjct: 1424 NYNLTVEATDGTTTILT---QVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISA 1480
Query: 2389 SDADASKNAVIRIIGGN------SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGS 2442
D D KN +I + + +F ++P+TG + TS LD E +TL V+ D
Sbjct: 1481 VDQD-EKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDV 1539
Query: 2443 PEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELH 2502
P + ++V V+D ND+ P F Y + GS V VT D D G N+E+
Sbjct: 1540 PVK-RNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVL 1598
Query: 2503 YSL-SGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFV 2559
YS+ SG F IDP+ G+I A L+ +++ + + VK D GS P ++ T+V + FV
Sbjct: 1599 YSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRI-FV 1657
Query: 2560 NKAD--FPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQL 2617
AD PK +KE + E + S V +T S + Y I GN G+ F I+
Sbjct: 1658 TIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHS--QSSVVYEIKDGNTGDAFDINPH 1715
Query: 2618 TGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISE 2677
+G + + LDFE + Y + I+ + S+ + + + D NDNAP+F + +
Sbjct: 1716 SGTIITQKALDFETLPIYTLIIQGTN--MAGLSTNTTVLVHLQDENDNAPVFMQAEYTGL 1773
Query: 2678 ILENLSPRKI--------LTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVR 2729
I E+ S + L + A D D N L Y IV ++ F+I+ +TG I +V
Sbjct: 1774 ISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVL 1833
Query: 2730 PLDREKVSHYVLTIKSSDKGSPS--QSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSP 2786
LD E+ S + T++ D G+P + V ++++D ND P F++ ++ A + +
Sbjct: 1834 SLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTY 1893
Query: 2787 LGYTVTRVTTSDEDIGINAISRYSIMDASL--PFTINPSTGDIVISRPLNREDTDRYRIR 2844
G V V +D D + YSI + ++ F+++ TG + + + RY +
Sbjct: 1894 KGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQN--TTQLRSRYELT 1951
Query: 2845 VSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSN 2904
V A D + T V I V + ++ +F++ Y E + + + A N
Sbjct: 1952 VRASDGRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAI--GNPIN 2009
Query: 2905 GQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLI 2964
+FY I + F+I+ T+G + T F +V ++ KPS +
Sbjct: 2010 EPLFYHILNPDRRFKISRTSGVLST-------TGTPFDREQQEAFDVVVEVTEEHKPSAV 2062
Query: 2965 SETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFIS 3024
+ V + + D NDNAP F+ Y+ V + +VG + VTA+ D+D G N EV Y++
Sbjct: 2063 AHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAV-DRDSGRNGEVHYYLK 2121
Query: 3025 NDNHLGKFKLDNDTGWISVASSL-ISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEEN 3083
H F++ G IS+ + LN+ + +TV AKD GNP S++ V ITV N
Sbjct: 2122 --EHHEHFQI-GPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVM--N 2176
Query: 3084 YHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSST 3143
P F + SA I ES + S V V A + + YSI+ G+ F IN +T
Sbjct: 2177 KAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLK---VFYSITDGDPFSQFTINFNT 2233
Query: 3144 GILTLAKALDYELCQKHEMTISAIDGGWVARTG-YCSVTVNVI--DVNDNSPVFLSDDYF 3200
G++ + LD+E ++++I A D + TG + V V++I D+NDN PVF Y
Sbjct: 2234 GVINVIAPLDFEAHPAYKLSIRATD----SLTGAHAEVFVDIIVDDINDNPPVFAQQSYA 2289
Query: 3201 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTV---QSSDSDLFVIDPNTGVITTQGFLD 3257
T+ E + GT+V+ + ATD+DS N I+Y + S D F +D +TG+I+ LD
Sbjct: 2290 VTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLD 2349
Query: 3258 FETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIV 3317
+E + + + V+A + S V + + N+ P F ++Y ISE AP G V
Sbjct: 2350 YEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFV 2409
Query: 3318 GEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK-VLAK 3376
V A D D ++ Y I + K F I+ TG I +S + R +LK +
Sbjct: 2410 TCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNL------HRHALKPFYSL 2463
Query: 3377 NFGSIRGADIDEVTVNVTVLDAN-DPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIP 3435
N G V+VTV+ N P F N Y V+++E P+ T V V D DS
Sbjct: 2464 NLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDS-G 2522
Query: 3436 SWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRET--LPIYNLSVLAVDSGTPSATGS 3493
+ +Y I + F IN + GQI +LDRET + ++ ++A D+G A +
Sbjct: 2523 IYGHVTYHIVNDFAKDRFYIN-ERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCT 2581
Query: 3494 ASLLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLST 3551
++++T D NDN P ++ EV + GT V+ + ++D D N TY + +
Sbjct: 2582 VNVILT--DDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSN-ADITYAIEAD 2638
Query: 3552 GPAT--SYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVI 3605
+ + +GV++T + + F V D+G P S V++ ++
Sbjct: 2639 SESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKIL 2694
Score = 774 bits (1999), Expect = 0.0
Identities = 675/2381 (28%), Positives = 1122/2381 (47%), Gaps = 170/2381 (7%)
Query: 25 LRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRP-------GFTYRLSES 77
L + W+ P + E F V+E P ++G I P T +S
Sbjct: 1341 LHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPLWFDITGGNYDS 1400
Query: 78 HALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPD 137
H F ++ TG + +D E + + + T T+V + V D ND+ P F
Sbjct: 1401 H--FDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFST 1458
Query: 138 PSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEG 197
V ED++ +++ +A D D N + + +FRLD
Sbjct: 1459 SKYEVVIPEDTAPETEILQISAVDQD-EKNKLIYTLQSSRDPLSLKKFRLD--------P 1509
Query: 198 AFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQA 257
A L + LD E Q+ L V V D+ P +R + ++ V V D ND+ P F +S Y+
Sbjct: 1510 ATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKG 1569
Query: 258 GVPEDAVVGSSVLQVAAADADEGTNADIRYRLQ--DEGTPFQMDPETGLITVREPLDFEA 315
V E A VGS VLQV A D D+G NA++ Y ++ + G F +DP G I + LD
Sbjct: 1570 RVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSN 1629
Query: 316 RRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVD--ENAQV 373
+ +Y L V+A D+G P ++ I + ++ P KF TS+ SV+ E +
Sbjct: 1630 QAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASP--KF-----TSKEYSVELSETVSI 1682
Query: 374 GTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPS 433
G+ V ++T S + +I GN F++ P+ I ALD E +P
Sbjct: 1683 GSFVGMVTAHSQSS------VVYEIKDGNTGDAFDIN----PHSGTIITQKALDFETLPI 1732
Query: 434 YNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSY 493
Y L + G + S+ ++++ + D ND+ PVF Q Y +SE A S
Sbjct: 1733 YTLIIQ---------GTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSV 1783
Query: 494 VSG-------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELAS 546
V I A D D NA L Y IV + +F I +G + T S LD E S
Sbjct: 1784 VLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLS--LDYEETS 1841
Query: 547 QIVLNISARDQGVHPKV---SYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELL 603
+ D G P++ A + V ++D+ND PVF++P Y+ S++ G +++
Sbjct: 1842 IFHFTVQVHDMGT-PRLFAEYAANVTVHVIDINDCPPVFAKPL-YEASLLLPTYKGVKVI 1899
Query: 604 MLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATD 663
+ ATD D + +S+ E + F +D +G L+ ++ + Y L V A+D
Sbjct: 1900 TVNATDADSSAFSQLIYSITEGNIGEK-FSMDYKTGALTVQNTTQLRSR--YELTVRASD 1956
Query: 664 LGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGT 723
+ + + +++ + ++ F Y A +KEN + ++A + N
Sbjct: 1957 ---GRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPI--NEP 2011
Query: 724 VKYSISAGDRSRFQVNAQSGVISTR-MALDREEKTAYQLQIVATDGGNLQSPNQAIVTIT 782
+ Y I DR RF+++ SGV+ST DRE++ A+ + + T+ + +V +
Sbjct: 2012 LFYHILNPDR-RFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVI 2070
Query: 783 VLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAIN 842
V D DN PVF + Y VV + +G+ + V+A D N + F I
Sbjct: 2071 VEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIG 2130
Query: 843 QVTGQLTTAN--VIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESV 900
+ G+++ +D + + V GG V + + +N P F + S
Sbjct: 2131 PL-GEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSA 2189
Query: 901 NVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLDVHA 959
+ E+ Q + +A P EG+ V YS+ +P + F IN G I+++ PLD A
Sbjct: 2190 EIAESIQVHSPVVHVQANSP-EGLK--VFYSITDGDPFSQFTINFNTGVINVIAPLDFEA 2246
Query: 960 -GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKV 1018
+Y++ I A+D + + V + + V D+NDN PVF Q SY VTLSE+ + + +V
Sbjct: 2247 HPAYKLSIRATD-SLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQV 2305
Query: 1019 QASDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASD 1074
+A+D DS N I+Y + GN + F G + + LD E ++ + V A D
Sbjct: 2306 RATDSDSEPNRGISYQMF-GNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVD 2364
Query: 1075 RAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGE 1134
+ LS+ V VTV + D+NDN PLF Y E G FV V A D D +
Sbjct: 2365 GGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDK 2424
Query: 1135 VRYSF--EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD 1192
++YS F + + +G IT ++ + R F ++ G+ +
Sbjct: 2425 LQYSILSGNDHKHFVIDSATGIITLSN-------LHRHALKPFYSLNLSVSDGV---FRS 2474
Query: 1193 QATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKG 1252
VHV + N ++P FL++ Y+ ++E+A T V+ V +D D G G + Y I+
Sbjct: 2475 STQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVND 2534
Query: 1253 NEERQFAIDSTSGQVTLIGKLDYEATPAYSLV---IQAVDSGTIPLNSTCTLNIDILDEN 1309
+ +F I+ GQ+ + KLD E TPA ++ + A D+G + CT+N+ + D+N
Sbjct: 2535 FAKDRFYINE-RGQIFTLEKLDRE-TPAEKVISVRLMAKDAG--GKVAFCTVNVILTDDN 2590
Query: 1310 DNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNN--HGTFSISP 1367
DN P F + V++ + G V V A+D+D G NAD+ Y+I + I+
Sbjct: 2591 DNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINK 2650
Query: 1368 NTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFK 1427
+G I + L + + A D G P + S + V + + P F
Sbjct: 2651 LSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTF 2710
Query: 1428 SIVENIPIGTSVISVTAHDPDADINGQLSYTIIQ----QMPRGNHFTIDEVKGTIYTNAE 1483
++ E++PIGT + + A+ +G + Y++++ + R F ID G +
Sbjct: 2711 TVSEDVPIGTEIDLIR-----AEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKS 2765
Query: 1484 IDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALA-ADPSAV 1542
+D E ++ ++ A + + A +V+I V D NDN P+F S A +
Sbjct: 2766 LDHETTKWYQFSILA--RCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLP 2823
Query: 1543 IGSVLTTIMAADPDEGANGEIEYEIINGDT----DTFIVDRYSGDLRVASALVPSQL-IY 1597
GS + I A+D D G NG++ Y + + ++F ++ +G + L + Y
Sbjct: 2824 GGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNY 2883
Query: 1598 NLIVSATDLGPERRKSTT---ELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA 1654
+ V A+D G + + S+T ++T+ P FT Y + E +P G VI+I +
Sbjct: 2884 QIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQG-GVIAILST 2942
Query: 1655 SPRGSE---APVEYYIVSVRCEEKTVGR--LFTIGRHTGIIQTAAILDREQGACLYLVDV 1709
+ SE V Y+I +G+ + TI ++ + LDRE+ YL+ +
Sbjct: 2943 TDADSEEINRQVTYFITG----GDPLGQFAVETI-QNEWKVYVKKPLDREK-RDNYLLTI 2996
Query: 1710 YAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADE 1769
A + + + +A VE+ + D NDN PV + T+ E++ G IMQ++A DAD
Sbjct: 2997 TATDGTF----SSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADI 3052
Query: 1770 GANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA-DDGLQSSDMRIN 1828
+NA +TYT++ + F+++P++G+L + LDRE ++ Y LLVRA D G + I
Sbjct: 3053 RSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQASIV 3112
Query: 1829 ITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGI 1888
+T+ DVND+ P+FS Y+ + E+T PG+L+ + ATD D+G+N +I Y + D DG
Sbjct: 3113 LTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSL-IDSADGQ 3171
Query: 1889 FFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG---GQFTTIRVYFNILDVNDNPPIFS 1945
F +N ++G+ L + LD E+Q Y L+++A D G T V ++LD+NDNPP+F
Sbjct: 3172 FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFE 3231
Query: 1946 LNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLK 2004
Y ++ E++ VG+ VL D N+++TYSI SG+ G+F++D K G + +++
Sbjct: 3232 YREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIE 3291
Query: 2005 ALDRESQSFYNLVVQVHD--LPQIPASRFTSTAQVSIILLDVNDNPPTFLSPK-LTYIPE 2061
LD ES Y L V+ D P + + A V++ + D+NDN P F T I E
Sbjct: 3292 NLDYESSHEYYLTVEATDGGTPSL-----SDVATVNVNVTDINDNTPVFSQDTYTTVISE 3346
Query: 2062 NTPIDTVVFKAQATDPDSGPNSYIEYTLLN-PLGNKFSIGTIDGEVRLTGELDREEVSNY 2120
+ ++ V A D D NS+I Y++++ G+ F+I + GEV++T LDRE +S Y
Sbjct: 3347 DAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGY 3406
Query: 2121 TLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAAD 2180
TLTV A+D G P ++T V + V D+NDN P+F++ Y V I EN G ++Q+ D
Sbjct: 3407 TLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTD 3466
Query: 2181 GDEGTNG-QVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPR 2239
D NG + IV GN + F ++ G + + + R++ Y L V+ D G
Sbjct: 3467 EDSSHNGPPFFFTIVTGNDEKAFEVNP-QGVLLTSSAIKRKEKDHYLLQVKVADNGKPQL 3525
Query: 2240 TDTSTVSIVLLDINDFVP-VFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYV 2298
+ + + I +++ + + P + L + + E I ++ A D D L+Y
Sbjct: 3526 SSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYS--GGVIGKIHATDQD--VYDTLTYS 3581
Query: 2299 LFGGNEDNAFTLSAS-GELGVTQSLDRETKERFVLMITATD 2338
L DN F++S++ G+L + LD +++L ++ TD
Sbjct: 3582 L-DPQMDNLFSVSSTGGKLIAHKKLD---IGQYLLNVSVTD 3618
Score = 589 bits (1518), Expect = e-167
Identities = 582/2047 (28%), Positives = 909/2047 (44%), Gaps = 237/2047 (11%)
Query: 1775 VTYTIISGADDSF--------------RIDPESGDLIATRRLDRERRSKYSLLVRADDGL 1820
V Y I+SG ++ RI + G+ T L+RE + Y+L+V+A +
Sbjct: 70 VRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGN---TAILNREVKDHYTLIVKALEKN 126
Query: 1821 QSSDMR--INITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITY 1878
+ + R + + V D ND P FS YS +PE+T + +A + ATD D G NGE Y
Sbjct: 127 TNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYY 186
Query: 1879 IVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-------GQFTTIRVY 1931
D +F ++P +GV LT LDY + Y + + A D G G + ++
Sbjct: 187 SFK--DRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLT 244
Query: 1932 FNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQL-TYSIASGDSLG 1990
+I N+ P+ + + S S ++ P + V V D D G N + + SI +GD L
Sbjct: 245 VHIEQANECAPVITAVTLSPSELDRDPAYAIV---TVDDCDQGANGDIASLSIVAGDLLQ 301
Query: 1991 QFTV------DKNGVLKVLKALDRESQSF-YNLVVQVHDLPQIPASRFTSTAQVSIILLD 2043
QF K +K + +D +S F YNL +Q D P +F+S + +
Sbjct: 302 QFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPP--QFSSVKVIHVTSPQ 359
Query: 2044 VNDNPPTFLSPKLT-----YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGN-KF 2097
P F + P NTP+ V+ KA S++ Y + G KF
Sbjct: 360 FKAGPVKFEKDVYRAEISEFAPPNTPV--VMVKAIPA------YSHLRYVFKSTPGKAKF 411
Query: 2098 SIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
S+ G + + + R++ +++ L V +D+ +ST+V+V VL N N P F Q
Sbjct: 412 SLNYNTGLISILEPVKRQQAAHFELEVTTSDR-----KASTKVLVKVLGANSNPPEFTQT 466
Query: 2158 LYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPL 2217
YK +EN GT ++ + A D DEG NG V Y I N N + F ID TGA++ ++ L
Sbjct: 467 AYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLN-HVPFAIDHFTGAVSTSENL 525
Query: 2218 DREKTP-TYHLTVQATDRGSTPRTDTSTV-SIVLLDINDFVPVFELSPYSVNVPENLGTL 2275
D E P Y L ++A+D G R + + +I L ++ND P+FE +P +LG +
Sbjct: 526 DYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLG-V 584
Query: 2276 PRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA-SGELGVTQSL--DRETKERF-V 2331
I V A D D + Y + GNE + F+L+ SG L + +SL K F
Sbjct: 585 GEQITTVSAIDAD--ELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHS 642
Query: 2332 LMITATDSGSPA--------------------------------------LTGTGTINVI 2353
L ITATD + A L G + I
Sbjct: 643 LRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDI 702
Query: 2354 VDD---VNDNVPTFASK-AYFTTIPEDAPTGTDVLLVNASDADASKNA--VIRIIGGN-- 2405
D VN ++P F S + E+ P G+ V+ +N++D D N V + GGN
Sbjct: 703 FFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNED 762
Query: 2406 SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPR 2465
S F I+ TG + + LDRET D YTL + D G P+ ++ + V V D NDNPP
Sbjct: 763 SCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQK-AAWRLLHVVVVDANDNPPE 821
Query: 2466 FQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAA 2525
F Y + S + V TD D+GPN + YS+ +++ F ID + G + A
Sbjct: 822 FLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIV-TDTDTFSIDSVTGVVNIA 880
Query: 2526 GPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFP-------E 2578
PL+ + S+ ++ + TV V K V TF+ P E
Sbjct: 881 RPLDRELQHEHSLKIEARDQAREEPQLFSTV--VVKVSLEDVNDNPPTFIPPNYRVKVRE 938
Query: 2579 NQPVSSLVTTITGSSL---RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKY 2635
+ P +++ + + + Y + GN F +D+L+G V I Q LDFEK Q Y
Sbjct: 939 DLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN-FDVDKLSGAVRIVQQLDFEKKQVY 997
Query: 2636 VVWIEARDGGFP-PFSSYEKLDITVLDVNDN--APIF---------KEDPFISEILENLS 2683
+ + A+D G P SS +++ V+DVN+N P+F KED + +
Sbjct: 998 NLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSL----- 1052
Query: 2684 PRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTI 2743
++TVSA D+D+ +G++ Y I +G+ F I TG I + LDRE SHY LT+
Sbjct: 1053 ---VMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTV 1109
Query: 2744 KSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIG 2802
++D+G S+ +++ I + D NDNAP+ S+ ++ + ENSP +V ++ D D
Sbjct: 1110 FATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSS 1169
Query: 2803 INAISRYSIMDASLP--FTINPSTGDI-VISRPLNREDTDRYRIRVSAHDSG---WTVST 2856
N Y I + F+I+P TG I SR L+RE D + + V+ D+G +
Sbjct: 1170 SNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIA 1229
Query: 2857 DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSK-------VTQVFATDPDEGSNGQVFY 2909
V + + D NDN P+F + Y + PE + + + V ATD DEG N ++ Y
Sbjct: 1230 RVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISY 1289
Query: 2910 FIKSQSEY--FRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET 2967
I+ +E+ F I TG + +K+ + G ++ + + D G+P S T
Sbjct: 1290 SIEDGNEHGKFFIEPKTGVVSSKRF----SAAGEYDI------LSIKAVDNGRPQKSSTT 1339
Query: 2968 TVTINIVDSNDNA--PQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN 3025
+ I + + P + +FT +I V +++ L + I+
Sbjct: 1340 RLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPL----WFDITG 1395
Query: 3026 DNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 3085
N+ F +D TG I VA L ++ N+ +TV A D G + +Q V I V + N H
Sbjct: 1396 GNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATD-GTTTILTQ--VFIKVIDTNDH 1452
Query: 3086 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEE---GIFAINSS 3142
P+FS S IPE + + + +SA D+D N LI Y++ S + F ++ +
Sbjct: 1453 RPQFSTSKYEVVIPEDTAPETEILQISAVDQD-EKNKLI-YTLQSSRDPLSLKKFRLDPA 1510
Query: 3143 TGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 3202
TG L ++ LD+E +H +T+ D + + + VNV D ND++P F + Y
Sbjct: 1511 TGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGR 1570
Query: 3203 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFETK 3261
V E+A G+ V+ + A D D G NA + Y+++S + + F+IDP G I T LD +
Sbjct: 1571 VYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQ 1630
Query: 3262 QSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVF 3321
Y L VKA + +V I + + P+F SK Y E+SE G+ VG V
Sbjct: 1631 AEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVT 1690
Query: 3322 ASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSI 3381
A + V Y I + F IN +G I LD E +L + N +
Sbjct: 1691 AH-----SQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGL 1745
Query: 3382 RGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHV-------TFVSAFDSDS 3433
TV V + D ND P+F Y+ ISE I + V + A D+D
Sbjct: 1746 S----TNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADK 1801
Query: 3434 IPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPS--AT 3491
S + Y I + + F+I+ TG I LD E I++ +V D GTP A
Sbjct: 1802 -DSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAE 1860
Query: 3492 GSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL 3549
+A++ V + DIND P+ + E ++ G V+T+ +TD D + Y +
Sbjct: 1861 YAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDAD--SSAFSQLIYSI 1918
Query: 3550 STGPATSYFSLS-TAGVLS-------------TTREIDREQIADFYLSVVTKDSGVPQMS 3595
+ G FS+ G L+ T R D + + K+S +
Sbjct: 1919 TEGNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASDGRFAGLTSVKINVKESKESHLK 1978
Query: 3596 STGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGV 3655
T V+ V+ +N +++ V + GN + + D F S TSGV
Sbjct: 1979 FTQDVYSAVVKENSTEAETLAV---ITAIGNPINEPLFYHILNPD----RRFKISRTSGV 2031
Query: 3656 TSLFSIP 3662
S P
Sbjct: 2032 LSTTGTP 2038
Score = 272 bits (696), Expect = 5e-72
Identities = 263/995 (26%), Positives = 456/995 (45%), Gaps = 115/995 (11%)
Query: 2699 PNGQLDYEIVNGNMENSFSIN-HATGEIRSVRP---------LDREKVSHYVLTIKSSDK 2748
P ++ Y+IV+G+ EN F + G+ +R L+RE HY L +K+ +K
Sbjct: 66 PAWEVRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEK 125
Query: 2749 GSPSQSTSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAIS 2807
+ ++ + KV + +LD ND P FS +S +PEN+ + ++ RV+ +D DIG N
Sbjct: 126 NTNVEART-KVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEF 184
Query: 2808 RYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHD--------SGWTVSTDVT 2859
YS D + F I+P++G IV++ L+ +T Y + + A D SG + +T
Sbjct: 185 YYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLT 244
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 2919
+ + N+ AP + + P + V D D+G+NG + + +
Sbjct: 245 VHIEQANECAPVITAVTL---SPSELDRDPAYAIVTVDDCDQGANGDIASLSIVAGDLLQ 301
Query: 2920 INATTGEIFNKQILKYQNVTGFSNVNINRHSF----IVTSSDRGKPSLISETTVTINIVD 2975
T + K + + G ++ + H F + + D+G P S V I++
Sbjct: 302 QFRTVRSFPGSKEYKVKAIGG---IDWDSHPFGYNLTLQAKDKGTPPQFSSVKV-IHVTS 357
Query: 2976 SNDNA--PQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFK 3033
A +F K Y +++ T ++ V AI S + Y + KF
Sbjct: 358 PQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIP-----AYSHLRYVFKSTPGKAKFS 412
Query: 3034 LDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSH 3093
L+ +TG IS+ + +F + VT D+ + V + V N + PEF+Q+
Sbjct: 413 LNYNTGLISILEPVKRQQAAHFELEVTTSDR-----KASTKVLVKVLGANSNPPEFTQTA 467
Query: 3094 MSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALD 3153
A E+ IG+ V ++SA D D NG + YSI++ N FAI+ TG ++ ++ LD
Sbjct: 468 YKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVP-FAIDHFTGAVSTSENLD 526
Query: 3154 YELCQK-HEMTISAIDGGW-VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGT 3211
YEL + + + I A D G R T+ + ++NDN+P+F + T+ + G
Sbjct: 527 YELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGE 586
Query: 3212 TVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQGFL--DFETKQSYHLTV 3268
+ ++A DAD ++ Y +++ ++ D F ++PN+GV++ + L K S+H
Sbjct: 587 QITTVSAIDADE--LQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFH--- 641
Query: 3269 KAFNVPDEERCSFAT--------------VNIQLKGT----------------------- 3291
+ + + +FAT VN+Q + T
Sbjct: 642 -SLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVE 700
Query: 3292 ---------NEYVPRFVSKL-YYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNS 3341
N ++P+F S L ++ E P G+ V + ++D D G +G++ Y + G +
Sbjct: 701 DIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGN 760
Query: 3342 RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND- 3400
F I+ +TG + + LDRE ++ +L + + G + A ++V V+DAND
Sbjct: 761 EDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWR--LLHVVVVDANDN 818
Query: 3401 PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTG 3460
PP F Y V++SE + + + V A D D P+ +Y I + + FSI+ TG
Sbjct: 819 PPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPN-GHVTYSIVT--DTDTFSIDSVTG 875
Query: 3461 QITVTAELDRETLPIYNLSVLAVDSG--TPSATGSASLLVTLEDINDNGPMLTVS--EGE 3516
+ + LDRE ++L + A D P + + V+LED+NDN P +
Sbjct: 876 VVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVK 935
Query: 3517 VMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQ 3576
V E+ GT++M L++ DPDL G Y LL G ++ +G + +++D E+
Sbjct: 936 VREDLPEGTVIMWLEAHDPDL-GQSGQVRYSLLDHGEG-NFDVDKLSGAVRIVQQLDFEK 993
Query: 3577 IADFYLSVVTKDSGVP-QMSSTGTVHITVIDQNDN 3610
+ L+V KD G P +SST V + V+D N+N
Sbjct: 994 KQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNEN 1028
Score = 124 bits (311), Expect = 2e-27
Identities = 59/171 (34%), Positives = 80/171 (46%), Gaps = 22/171 (12%)
Query: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
+ C PCQNGG C P + CKC Y G+ CEI +
Sbjct: 4015 EDCASNPCQNGGVC---------------------NPSPAGGYYCKCSALYIGTHCEISV 4053
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 3923
+ C PC GGTC GGF C C +TG+ C+ C PCKNG C +
Sbjct: 4054 NPCSSKPCLYGGTCVVDNGGFVCQCRGLYTGQRCQLS-PYCKDEPCKNGGTCFDSLDGAV 4112
Query: 3924 CVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCE 3974
C C +G+ G+ C+S ++ C NPC +G C++ SY+C+C G+HCE
Sbjct: 4113 CQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCE 4163
Score = 110 bits (275), Expect = 3e-23
Identities = 92/362 (25%), Positives = 152/362 (41%), Gaps = 54/362 (14%)
Query: 4158 QCPRLEGACTRSPCQHGGTCM-DYWSWQQ-CHCKEGLTGKYCEKSVTPDTALSLEGKGRL 4215
+CP + C PC G C+ D W + C C G G+ C S ++++L G +
Sbjct: 3786 RCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQ-CPGS----SSMTLTGNSYV 3840
Query: 4216 DYHMSQNEKREYLLRQSLRGAMLEPFGVNSLEVKFRTRSENGVLIHIQESSNYTTVKIKN 4275
Y +++NE + + L ++ RT S + V+++ + ++Y+ ++I +
Sbjct: 3841 KYRLTENENKLEM----------------KLTMRLRTYSTHAVVMYAR-GTDYSILEIHH 3883
Query: 4276 GKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDF 4335
G++ + D G +G ++ + V DG WH + NG L +D+++ P
Sbjct: 3884 GRLQYKFDCG-SGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAP---- 3938
Query: 4336 GGLDVLTIS----LGGIPPNQAHRDAQTA----GFDGCIASMWYGGESLPFSGKHSLASI 4387
G L L + GG Q R ++ GF GC+ S++ G+ LP + K +
Sbjct: 3939 GTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAH 3998
Query: 4388 SKTDPSVKIGC--RGPNICASNPCWGDLLCINQ---WYAYRC----------VPPGDCAS 4432
+ V GC CASNPC +C Y +C + C+S
Sbjct: 3999 IEESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSS 4058
Query: 4433 HPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEMVVACLGVLCPQGKVCKAGSPAGHVCVLS 4492
PC GG+C + GF C C +TG+ C++ C C G C S G VC
Sbjct: 4059 KPCLYGGTCVVD-NGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTC-FDSLDGAVCQCD 4116
Query: 4493 QG 4494
G
Sbjct: 4117 SG 4118
Score = 81.3 bits (199), Expect = 2e-14
Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 36/296 (12%)
Query: 3924 CVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGV--DSYYCHCPFGVFGKHCELNSYGFE 3981
C+CK G C + CE +PC G C S + + C CP G FG+ +S
Sbjct: 3780 CLCKEG----RCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLT 3835
Query: 3982 ELSYMEFPSLDPNNNYIYVKFA----TIKSHALLLYNYDNQTGDRAEFLALEIAEERLRF 4037
SY+++ L N N + +K T +HA+++Y ++ LEI RL++
Sbjct: 3836 GNSYVKY-RLTENENKLEMKLTMRLRTYSTHAVVMY------ARGTDYSILEIHHGRLQY 3888
Query: 4038 SYNLGSGTYKLTTMK-KVSDGHFHTVIARRAGMAASLTVDSCSENQEPGYCTVSNVAVSD 4096
++ GSG ++ +V+DG +H V G A L +D T S A
Sbjct: 3889 KFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVH--------TASGTAPGT 3940
Query: 4097 DWTLDVQPNRVTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPL----EPSQALAA 4152
TL++ N V GG + R + F GC+ +NG+ L +P
Sbjct: 3941 LKTLNLD-NYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHI 3999
Query: 4153 QGILDQCP----RLEGACTRSPCQHGGTC-MDYWSWQQCHCKEGLTGKYCEKSVTP 4203
+ +D P C +PCQ+GG C C C G +CE SV P
Sbjct: 4000 EESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNP 4055
Score = 68.9 bits (167), Expect = 1e-10
Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 3903 ECLQSPCKNGAICQNFP-GSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYY 3961
+C +PC+NG +C P G + C C Y G CE SVN C PC GG+C +
Sbjct: 4016 DCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGFV 4075
Query: 3962 CHCPFGVFGKHCELNSYGFEE 3982
C C G+ C+L+ Y +E
Sbjct: 4076 CQCRGLYTGQRCQLSPYCKDE 4096
Score = 38.9 bits (89), Expect = 0.13
Identities = 14/41 (34%), Positives = 20/41 (48%)
Query: 4161 RLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCEKSV 4201
+L C PC++GGTC D C C G G+ C+ +
Sbjct: 4088 QLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDI 4128
Score = 37.4 bits (85), Expect = 0.38
Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
Query: 4398 CRGPNICASNPCWGDLLCINQWYAYRCVPPGD-CASHPCQNGGSCEPGLHSGFTCSCPDS 4456
C+ C + C + + RC D C+ +PC +G CE H + C+C
Sbjct: 4098 CKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCE-NTHGSYHCNCSHE 4156
Query: 4457 HTGRTCE 4463
+ GR CE
Sbjct: 4157 YRGRHCE 4163
Score = 33.9 bits (76), Expect = 4.2
Identities = 12/42 (28%), Positives = 20/42 (47%)
Query: 4157 DQCPRLEGACTRSPCQHGGTCMDYWSWQQCHCKEGLTGKYCE 4198
++C C+ +PC HG C + C+C G++CE
Sbjct: 4122 ERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCE 4163
>gi|16933557 dachsous 1 precursor [Homo sapiens]
Length = 3298
Score = 1152 bits (2981), Expect = 0.0
Identities = 895/2945 (30%), Positives = 1397/2945 (47%), Gaps = 194/2945 (6%)
Query: 582 FSQPEGYDVSVVENAPTGTELLMLRATDGDLGDN---GTVR-----FSLQEAETDRRSFR 633
+ Q D+ + E P GT + GD+ GT S QE
Sbjct: 41 WGQAGSLDLQIDEEQPAGTLI-------GDISAGLPAGTAAPLMYFISAQEGSGVGTDLA 93
Query: 634 LDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQ 693
+D SG + T LDRE++ Y + P + + V + DIND++P F +
Sbjct: 94 IDEHSGVVRTARVLDREQRDRYRFTAVT------PDGATVEVTVRVADINDHAPAFPQAR 147
Query: 694 YFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISA-GDRSRFQVNAQSGVISTRMA-- 750
+ E+ G+ A D D G GT Y++S G F++ + G T +
Sbjct: 148 AALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPEL 207
Query: 751 -----LDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFEN 805
LDRE ++ Y LQ+ A DGG+ QA++ +T+LD D+ P F+Q Y VV E+
Sbjct: 208 VVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSES 267
Query: 806 VALGYHVGSVSASTMD--LNSNISYLITTGDQKG--MFAINQVTGQLTTANVIDREEQSF 861
+A G V V AS D +N ++Y I +G F+I+ TG L +D E++
Sbjct: 268 LAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRV 327
Query: 862 YQLKVVASGGTV---TGDTMVNITVKDLNDNSPH----FLQAIESVNVVENWQAGHSIFQ 914
++L V A G G V + V+D NDN P FL A S V E G + +
Sbjct: 328 HELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVAR 387
Query: 915 AKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLL---GPLD-VHAGSYQIEILASD 970
DPD+G V SL + + FA++ ++ I L+ LD +Y + + A+D
Sbjct: 388 ISVSDPDDGDFAHVNVSL-EGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATD 446
Query: 971 MGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVT-LSESEPVNSRFFKVQASDKDSGANG 1029
G P L + ++V DVNDN+P FD+ Y L E S +V A D D G NG
Sbjct: 447 SGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNG 506
Query: 1030 EIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTV 1088
++ Y++A G F I P G + + LD EL+ + L+VVA+D + PL+++ V+V
Sbjct: 507 QVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSV 566
Query: 1089 ILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF-----EMVQ 1143
L+DVNDN P F T Y E + G+ +V+A D D GP G + YS
Sbjct: 567 ALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGS 626
Query: 1144 PDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDI 1203
P F + A SG++ T DR+ +G + F FTV A D G LK V V++ D
Sbjct: 627 PPFRIDAHSGDVCTTRTLDRD-----QGPSSFDFTVTAVDGG---GLKSMVYVKVFLSDE 678
Query: 1204 NDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDST 1263
NDN P+F Y A+IS + T VLR+ A D D+G++G + Y I+ GN F +D
Sbjct: 679 NDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQ 738
Query: 1264 SGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVD 1323
SG +T+ L A L I A D G + + ++I I+ P F +
Sbjct: 739 SGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFS 798
Query: 1324 VLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQ 1383
V E++ G V V A + G A + S++G + G FS+ +G + + LD E
Sbjct: 799 VPEDVAPGTSVGIVQA-HNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELL 857
Query: 1384 S-LYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISV 1442
+ +L + A G PP + V + + D NDN P+FP + + N GT + ++
Sbjct: 858 GPVLELEVRA-GSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTL 916
Query: 1443 TAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQA 1502
A DPD+ +N ++++T++ G FT+D G + + EL ++A D
Sbjct: 917 RALDPDSGVNSRVTFTLLAG--GGGAFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGG 974
Query: 1503 VPIETRRYALKNVTILVTDLNDN--VPMFISQNALAADPSAVI-GSVLTTIMAADPDEGA 1559
P T + L+ ++V D+ P F S PS G+ + + A PD
Sbjct: 975 SPPRTSHFRLR---VVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPD--- 1028
Query: 1560 NGEIEYEII-NGDTDTFIVDRYSGDLRVASALV-PSQLIYNLIVSAT-----DLGPERRK 1612
G I Y + G + F ++ SG L V +AL +Q +Y L V A +LG +
Sbjct: 1029 GGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGT 1088
Query: 1613 STTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYYIVSVR 1671
+T ++I+ Q P ++ + E +P GT+V + A G + Y + +
Sbjct: 1089 ATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLS 1148
Query: 1672 CEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQ 1731
+ K F I TG + T LDREQ + L+ ++ + PR+ V + +
Sbjct: 1149 EDSKA----FRIHPQTGEVTTLQTLDREQQSSYQLL--VQVQDGGSPPRSTTGTVHVAVL 1202
Query: 1732 DINDNPPVFPTDM------LDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADD 1785
D+NDN P F L + V + + G+ + L A D DEG N + YT+ +
Sbjct: 1203 DLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSE 1262
Query: 1786 SFRIDPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITV----------S 1832
F + P SG+L+ L R R Y L + A D +S+ +++ + V
Sbjct: 1263 LFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPP 1322
Query: 1833 DVNDHTPKFSRPVY-SFDIPEDTIPGSLVAAILATDDDSGVNGEITY-IVNEDDEDGIFF 1890
D+ + P PV + E PGSL+ ++ A + +GV G +TY +V D +G F
Sbjct: 1323 DLAERDPAAPVPVVLTVTAAEGLRPGSLLGSV-AAPEPAGV-GALTYTLVGGADPEGTFA 1380
Query: 1891 LNPITGVFNLTRLLDYEV-QQYYILTVRAED-GGGQFTTIRVYFNILDVNDNPPIFSLNS 1948
L+ +G L R LD+E + LTVRAE GG +RV + D N++ P F+ +
Sbjct: 1381 LDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDP 1440
Query: 1949 YSTSLMENLPVGSTVLVFNVTDADD-GINSQLTYSIASGDS-LGQFTVD-KNGVLKVLKA 2005
+ +L EN G+ + F +DAD G NS + Y + + + +D + G L +
Sbjct: 1441 LALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRG 1500
Query: 2006 LDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPI 2065
LDRE+ L+V+ D P + R + + + D NDN P F SP +PE+ P
Sbjct: 1501 LDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASPSRVRLPEDQPP 1560
Query: 2066 DTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVV 2125
A DPD G + + Y L + F + + G + + LDRE+ + + LTVV
Sbjct: 1561 GPAALHVVARDPDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVV 1620
Query: 2126 ATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGT 2185
A+D G P S++ + V V D+ND P F Q Y V + EN GT ++ + A D D G
Sbjct: 1621 ASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGA 1680
Query: 2186 NGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTV 2245
NGQV YG G +++ F +D TG +T + LDRE+ +LTV A DRGS P+ TV
Sbjct: 1681 NGQVTYG---GVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTV 1737
Query: 2246 SIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNED 2305
+ + D ND P F + S+ VPE G P+T+ + A D D G+N +L Y + G+
Sbjct: 1738 RVAVEDENDHAPTFGSAHLSLEVPE--GQDPQTLTMLRASDPDVGANGQLQYRILDGDPS 1795
Query: 2306 NAFTLS-ASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTF 2364
AF L ASGE G + LDRE + F L I A D G PAL+ T + V V D ND+ P F
Sbjct: 1796 GAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAF 1855
Query: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRI---IGGNSQFTINPSTGQIITSA 2421
AY +PED P GT +L + A D DA N + G F + PS+G++ T+A
Sbjct: 1856 PVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAA 1915
Query: 2422 LLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSP--- 2478
LDRE +YT V D + PLS++ SV +TV DVND+ P F P +P P
Sbjct: 1916 ALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPS 1975
Query: 2479 -TLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAI-MAAGPLN-GASEVT 2535
+ P + + D D G N+ + Y L+G +D G I +A P+ G +
Sbjct: 1976 FSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRV 2035
Query: 2536 FSVHVKDGGSFPKTDSTTVTVRFVNKAD----FPKVRAKEQTFMFPENQPVSSLVTTITG 2591
+ D G ++ + + V +A+ FP+ + E T EN P + + +
Sbjct: 2036 LFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRA-SSEATIR--ENAPPGTPIVSPRA 2092
Query: 2592 SSLRGE--PMSYYIASGNLGNTFQIDQLTGQVSI--SQPLDFEKIQKYVVWIEARDGGFP 2647
G P++Y I SGN TF I TG +++ ++ LDFE + + ++A GG
Sbjct: 2093 VHAGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAF 2152
Query: 2648 PFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLS-PRKILTVSAMDKDSGPNGQLDYE 2706
F+ L +T+ D NDNAP F +++ + E+ +L V A D D G GQ+ Y
Sbjct: 2153 AFT---VLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYS 2209
Query: 2707 IVNGN-MENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILD 2765
+ F ++ TG I + LDRE + L + ++D+GSP+ S + + ++D
Sbjct: 2210 LAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVID 2269
Query: 2766 ENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTG 2825
NDN P Q + V E++ LG + +VT +D D G S PF++ G
Sbjct: 2270 TNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQDPFSVGRYGG 2329
Query: 2826 DIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELT 2885
+ ++ PL+ E DRY++++ AHD ++T+ V D+NDNAP FS++ Y + E T
Sbjct: 2330 RVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHT 2389
Query: 2886 EIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVN 2945
GS + V ATD D G+NG + Y + S ++ F ++ G +F G V+
Sbjct: 2390 PPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVD 2449
Query: 2946 INRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRV 3005
+ ++ + D G P + TV + + D ND+AP F S Y VT+++ G+ L+ +
Sbjct: 2450 V-----VLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTL 2504
Query: 3006 TAIDDKDFGLNSEVEYFISNDNHLGKFKLD--------------NDTGWISVASSLISDL 3051
A D ++ V+Y I + N F+L+ G + + L +
Sbjct: 2505 EATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFES 2564
Query: 3052 NQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
+ +TV A D+G PP SS V +TV + N + P F+++ T+PE +G+ + V
Sbjct: 2565 LTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHV 2624
Query: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
A D D +GL+++++SSG+ G+F ++ S+G L LA ALD E +H++ + A D
Sbjct: 2625 EASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAG 2684
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAY 3231
A VT+ V DVND+ P F + +V EN P GT V L+A D D+G + Y
Sbjct: 2685 -AHFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRY 2743
Query: 3232 TVQSS-----DSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNI 3286
++ + + F ++ +TG + + D+E +S+ L V A + + + TV++
Sbjct: 2744 SLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGN--LSASVTVSV 2801
Query: 3287 QLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGF 3346
+ G +EY P F++ ++F++ E A +G +G V A+D D G DG V Y + +S F
Sbjct: 2802 LVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSS--PYF 2859
Query: 3347 QINKKTGQIYV----------------SGILDREKEERVSLKVLAKNFGSIRGADIDEVT 3390
IN+ TG +Y+ G RE + L+V+A+ G + G+ V
Sbjct: 2860 GINQTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVIAR--GPLPGSRSATVP 2917
Query: 3391 VNVTV 3395
V V +
Sbjct: 2918 VTVDI 2922
Score = 1116 bits (2886), Expect = 0.0
Identities = 916/2936 (31%), Positives = 1389/2936 (47%), Gaps = 188/2936 (6%)
Query: 5 PDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTI 64
P + RP L L L LL + L + +PG AW G Q+ EEQP GTL+G I
Sbjct: 12 PGMKSPRPHLLLPLL----LLLLLLLGAGVPG-AW--GQAGSLDLQIDEEQPAGTLIGDI 64
Query: 65 Q------TRPGFTYRLSESHAL-----FAINSSTGALYTTSTIDRESLPSDVINLVVLSS 113
T Y +S AI+ +G + T +DRE V
Sbjct: 65 SAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPDG 124
Query: 114 APTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRS 173
A EV V V D+ND+AP FP + E ++ G + L+ A D+D G G +
Sbjct: 125 ATV---EVTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYA 181
Query: 174 YRIIRGNEAGR-FRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRG 232
+ G+ AG FRL+ P G LV G LDRE Y L +E D G P RR
Sbjct: 182 ---LSGDGAGETFRLETRPGPDGTPV-PELVVTGELDRENRSHYMLQLEAYDGGSPPRRA 237
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRY---RL 289
++VT+ DIND+ P F S Y A V E GS VLQV A+DAD G N + Y R
Sbjct: 238 QALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRR 297
Query: 290 QDEGT-PFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVND 348
Q EG PF +D TGL+ + PLDFE RR + L VQA D G G A + + D ND
Sbjct: 298 QSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDAND 357
Query: 349 NDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFE 408
N P + + A V E A G +VA ++V+D D +++V + GG + HF
Sbjct: 358 NQPSMTVIFLSADGS-PQVSEAAPPGQLVARISVSDPDD-GDFAHVNVSLEGG--EGHFA 413
Query: 409 VQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDI 468
+ S++ + L+ VA LDRE +YNL V+ +D+ G+PP A A+ V+ V D+
Sbjct: 414 L-STQDSVIYLVCVARRLDREERDAYNLRVTATDS-GSPPLRA------EAAFVLHVTDV 465
Query: 469 NDHPPVFSQQVYRVN-LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISE 527
ND+ P F +Q+YR L E A PGS+V ++A D D G N + YS+ G WF I
Sbjct: 466 NDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDP 525
Query: 528 HSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEG 587
SG++TT +S LD EL Q L + A D G+ P S A + V L DVND +P F Q
Sbjct: 526 TSGIITTAAS--LDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQF-QRTF 582
Query: 588 YDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQE--AETDRRSFRLDPVSGRLSTIS 645
Y+ S+ E GT L + ATD D G G + +SL + FR+D SG + T
Sbjct: 583 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTR 642
Query: 646 SLDREE-QAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPG 704
+LDR++ + + V A D G SM + V L D NDN P FYP +Y A I P
Sbjct: 643 TLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVFLSDENDNPPQFYPREYAASISAQSPP 700
Query: 705 GSYITTVSATDPDLGTNGTVKYSISAGDR-SRFQVNAQSGVISTRMALDREEKTAYQLQI 763
G+ + + A DPD G++G + Y I AG+ F ++ QSG+++ L R + QL+I
Sbjct: 701 GTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLTVAWPLARRANSVVQLEI 760
Query: 764 VATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSA-STMDL 822
A DGG LQ+ A V I+++ PP+F Q+ Y F V E+VA G VG V A +
Sbjct: 761 GAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPGR 820
Query: 823 NSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQS-FYQLKVVASGGTVTGDTM--V 879
+ ++ ++ GD +G+F+++ V+G L T +DRE +L+V A G + V
Sbjct: 821 LAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARV 880
Query: 880 NITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNL 939
+ + D+NDNSP F ++V + N G I+ +A+DPD GVN V ++L
Sbjct: 881 RVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGGA 940
Query: 940 FAINEKNGTISLLGPLDVHAG-SYQIEILASDMGVPQLSSSVILTVYVHDVNDN--SPVF 996
F ++ G + L+ PL G ++++E+ A D G P +S L V V DV +P F
Sbjct: 941 FTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRF 1000
Query: 997 DQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIK 1055
+ +Y V L ++ +VQA D G I Y +A FG+ P G L+++
Sbjct: 1001 NSPTYRVDLPSGTTAGTQVLQVQAQAPD---GGPITYHLAAEGASSPFGLEPQSGWLWVR 1057
Query: 1056 SELDRELQDRYVLMVVA---SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEE 1112
+ LDRE Q+ Y+L V+A S + + T V V + + N++ P + E
Sbjct: 1058 AALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAEN 1117
Query: 1113 QRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD---FELHAISGEITNTHQFDRESLMRR 1169
Q G+ VG+V A D+D GPNG + YS + + D F +H +GE+T DRE
Sbjct: 1118 QPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQ---- 1173
Query: 1170 RGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQA------TISESA 1223
+ + V D G P P TVHV + D+NDN+P FL+ A + +
Sbjct: 1174 --QSSYQLLVQVQDGGSP-PRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRV 1230
Query: 1224 ANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSL 1283
T V + A D DEG NG I Y+ + G F++ SG++ L P Y L
Sbjct: 1231 PPGTLVTTLQAKDPDEGENGTILYT-LTGPGSELFSLHPHSGELLTAAPLIRAERPHYVL 1289
Query: 1284 VIQAVDSGTIPLNSTCTLNIDIL----------DENDNTPSFP-KSTLFVDVLENMRIGE 1332
+ A D G+ P +++ L + +L D + P+ P L V E +R G
Sbjct: 1290 TLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGS 1349
Query: 1333 LVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYK-LNIT 1391
L+ SV A + +G A Y + G + GTF++ +G ++LA+ LDFE ++ L +
Sbjct: 1350 LLGSVAAPE-PAGVGALTYTLVGGADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVR 1408
Query: 1392 AKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDA-D 1450
A+ G + + V + V+D N++ P+F + ++ EN G ++ + A D D
Sbjct: 1409 AEGPG-GAGARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPG 1467
Query: 1451 INGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRY 1510
N + Y +++Q P +D G + +DRE L V+A D+ RR
Sbjct: 1468 PNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRA 1527
Query: 1511 ALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIING 1570
A + + VTD NDN P+F S + + G ++A DPD G + Y + +G
Sbjct: 1528 ARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASG 1587
Query: 1571 DTDTFIVDRYSGDLRVASALVPSQLI-YNLIVSATDLGPERRKSTTELTIILQGL--DGP 1627
F + +G L V L Q + L V A+D G R +T LT+ + + + P
Sbjct: 1588 GDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAP 1647
Query: 1628 VFTQPKYITILKEGEPIGTNVISIEAASPR-GSEAPVEYYIVSVRCEEKTVGRLFTIGRH 1686
F Q +Y +L+E P GT+++++ A P G+ V Y VS F++
Sbjct: 1648 TFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTYGGVS--------SESFSLDPD 1699
Query: 1687 TGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLD 1746
TG++ T LDRE+ + L VYA ++ + P+ V + ++D ND+ P F + L
Sbjct: 1700 TGVLTTLRALDREEQEEINLT-VYAQDRGSP-PQLTHVTVRVAVEDENDHAPTFGSAHLS 1757
Query: 1747 LTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRE 1805
L V E D + L A D D GAN + Y I+ G +F +D SG+ R LDRE
Sbjct: 1758 LEVPEG-QDPQTLTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTMRPLDRE 1816
Query: 1806 RRSKYSLLVRADDGLQ---SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAA 1862
+ L + A DG Q S+ + + +TV D NDH P F P YS ++PED G+L+
Sbjct: 1817 VEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQ 1876
Query: 1863 ILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDG- 1921
+ A D D+G NG +TY + G F L P +G LD E Y +V A DG
Sbjct: 1877 LQAHDPDAGANGHVTYYLGAGTA-GAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGA 1935
Query: 1922 --GGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGST----VLVFNVTDADDGI 1975
G TT+ V + DVND+ P F + L P ST + D D G
Sbjct: 1936 AAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGA 1995
Query: 1976 NSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTA 2035
N+ + Y +A G G ++V ++ L + DL + PA ++T
Sbjct: 1996 NASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGR-PAR--SATG 2052
Query: 2036 QVSIILLDVNDNPPTF--LSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPL 2093
+ + L + P F S + T I EN P T + +A G N I Y++L+
Sbjct: 2053 VIIVGLQGEAERGPRFPRASSEAT-IRENAPPGTPIVSPRAVHA-GGTNGPITYSILS-- 2108
Query: 2094 GNK---FSIGTIDG--EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDIN 2148
GN+ FSI G VR LD E L + A G + T + + + D N
Sbjct: 2109 GNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGG---AFAFTVLTLTLQDAN 2165
Query: 2149 DNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQE-FRIDSV 2207
DN P F + Y + E+ ++QV A D D+G+ GQ+ Y + + F +D
Sbjct: 2166 DNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPT 2225
Query: 2208 TGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVN 2267
TG IT LDRE L + ATDRGS ++T++++++D ND P P+ +
Sbjct: 2226 TGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIP-QPWELR 2284
Query: 2268 VPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA-SGELGVTQSLDRET 2326
V E+ L I QV D D G L YVL + F++ G + +T LD E
Sbjct: 2285 VSED-ALLGSEIAQVTGNDVDSG--PVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQ 2341
Query: 2327 KERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLV 2386
+R+ L + A D G + V+V+DVNDN P F+ Y + E P G+ +L V
Sbjct: 2342 CDRYQLQLLAHDGPH---EGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSV 2398
Query: 2387 NASDADASKNAVI--RIIGGNSQFTINPSTGQIIT---SALLDRETKDNYTLVVVCSDAG 2441
+A+D D+ N I + F+++P+ G + T + L + +V+ D G
Sbjct: 2399 SATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHG 2458
Query: 2442 SPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDAD-IGPNSE 2500
+P + +T V V + D ND+ P F Y + PGS + + TDAD ++
Sbjct: 2459 APGRAARAT-VHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAA 2517
Query: 2501 LHYS-LSGRNSEKFHIDP-LRGAIMAAGP---------------LNGASEVTFSVHVKDG 2543
+ YS +SG F ++P L A +AGP ++ +V D
Sbjct: 2518 VDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADR 2577
Query: 2544 GSFPKTDSTTVTVRFVNKADFPKVRAK-EQTFMFPENQPVSSLVTTITGSSLRGEP---M 2599
G P++ VTV ++ D P V + PE+ PV + + + S P +
Sbjct: 2578 GQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLV 2637
Query: 2600 SYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITV 2659
+ ++SG+ F++D+ +G + ++ LD E ++ + ++A D F + + I V
Sbjct: 2638 RFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHF-ALAPVTIEV 2696
Query: 2660 LDVNDNAPIFKEDPFISEILENLSPRKIL-TVSAMDKDSGPNGQLDYEIVNGNM----EN 2714
DVND+ P F + + + EN P ++ T+ A+D D+G G+L Y ++
Sbjct: 2697 QDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGRE 2756
Query: 2715 SFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRF- 2773
+F++N +TGE+R+ P D E + L + ++D G+ S S +V V++ DE D P F
Sbjct: 2757 AFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYD--PVFL 2814
Query: 2774 SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTGDIVI 2829
+ F VPE + G+++ V +DED G + + YS+ +S F IN +TG + +
Sbjct: 2815 APAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYL 2870
Score = 933 bits (2411), Expect = 0.0
Identities = 839/2894 (28%), Positives = 1314/2894 (45%), Gaps = 209/2894 (7%)
Query: 804 ENVALGYHVGSVSAST-MDLNSNISYLITTGDQKGM---FAINQVTGQLTTANVIDREEQ 859
E G +G +SA + + Y I+ + G+ AI++ +G + TA V+DRE++
Sbjct: 53 EEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQR 112
Query: 860 SFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVD 919
Y+ V G V + V D+ND++P F QA ++ V E+ G A D
Sbjct: 113 DRYRFTAVTPDGATVE---VTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPARD 169
Query: 920 PDEGVNGMVLYSLK-QNPKNLFAINEKNGT-------ISLLGPLDVHAGS-YQIEILASD 970
D G G Y+L F + + G + + G LD S Y +++ A D
Sbjct: 170 ADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAYD 229
Query: 971 MGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGE 1030
G P + +L V + D+ND++P F+Q Y +SES S +V ASD D+G NG
Sbjct: 230 GGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGA 289
Query: 1031 IAYTIAEGNT-GDA-FGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVT 1087
+ Y I + GD F I G L ++ LD E + + L+V A D P + VT
Sbjct: 290 VTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVT 349
Query: 1088 VILEDVNDNRP----LFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQ 1143
V + D NDN+P +F S + + E G V ++S D D G V S E +
Sbjct: 350 VHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGE 409
Query: 1144 PDFELHAISGEI---TNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYM 1200
F L I + DRE ++ V ATD G P PL+ +A +++
Sbjct: 410 GHFALSTQDSVIYLVCVARRLDREE------RDAYNLRVTATDSGSP-PLRAEAAFVLHV 462
Query: 1201 KDINDNAPKFLKDFYQAT-ISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFA 1259
D+NDNAP F + Y+ + E A + V+RV+A D D+G NG + YS+ G F+
Sbjct: 463 TDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFS 522
Query: 1260 IDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKST 1319
ID TSG +T LDYE P L++ A D G PL S+ T+++ + D NDN P F ++
Sbjct: 523 IDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTF 582
Query: 1320 LFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI---TGTNNHGTFSISPNTGSIFLAK 1376
+ E + G VTATD+DSG L YS+ G++ F I ++G + +
Sbjct: 583 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTR 642
Query: 1377 KLDFET-QSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI 1435
LD + S + +TA D G S + V + + D NDNPP F P + SI P
Sbjct: 643 TLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVFLSDENDNPPQFYPREYAASISAQSPP 700
Query: 1436 GTSVISVTAHDPDADINGQLSYTIIQQMPRGNH---FTIDEVKGTIYTNAEIDREFANLF 1492
GT+V+ + AHDPD +G+LSY I+ GN FT+DE G + + R ++
Sbjct: 701 GTAVLRLRAHDPDQGSHGRLSYHILA----GNSPPLFTLDEQSGLLTVAWPLARRANSVV 756
Query: 1493 ELTVKAND----QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLT 1548
+L + A D QA P V I + P+F + + P V
Sbjct: 757 QLEIGAEDGGGLQAEPSA-------RVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSV 809
Query: 1549 TIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASALVPSQL--IYNLIVSATD 1605
I+ A G + + GD F +D SG L+ L L + L V A
Sbjct: 810 GIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGS 869
Query: 1606 LGPERRKSTTELTIILQGLD--GPVFTQPKYITILKEGEPIGTNVISIEAASP-RGSEAP 1662
G + + ++L ++ P F P+ +L GT + ++ A P G +
Sbjct: 870 -GVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSR 928
Query: 1663 VEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQ 1722
V + +++ G FT+ TG ++ L G + +++ A + + PRT
Sbjct: 929 VTFTLLAGG------GGAFTVDPTTGHVRLMRPLGPSGGPA-HELELEARDGGSP-PRTS 980
Query: 1723 RAEVEITLQDINDN--PPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII 1780
+ + +QD+ P F + + + G++++Q+ A D G +TY +
Sbjct: 981 HFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGGP---ITYHLA 1037
Query: 1781 S-GADDSFRIDPESGDLIATRRLDRERRSKYSLLV------RADDGLQSSDMRINITVSD 1833
+ GA F ++P+SG L LDRE + Y L V +A+ G Q+ + +++ +
Sbjct: 1038 AEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILN 1097
Query: 1834 VNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDG-IFFLN 1892
N+H+P+ S + E+ PG+ V + ATD DSG NG +TY + + ED F ++
Sbjct: 1098 QNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIH 1157
Query: 1893 PITGVFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVYFNILDVNDNPPIFSLNSYS 1950
P TG + LD E Q Y L V+ +DGG + TT V+ +LD+NDN P F S +
Sbjct: 1158 PQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGA 1217
Query: 1951 TS------LMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLK 2004
+ + +P G+ V D D+G N + Y++ S +G L
Sbjct: 1218 AGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHSGELLTAA 1277
Query: 2005 ALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTP 2064
L R + Y L + HD P S V ++ PP L+ + P P
Sbjct: 1278 PLIRAERPHYVLTLSAHDQGSPPRSASLQLL-VQVLPSARLAEPPPDLAERDPAAP--VP 1334
Query: 2065 IDTVVFKAQATDPDSGPNSY----------IEYTLL---NPLGNKFSIGTIDGEVRLTGE 2111
+ V A+ P S S + YTL+ +P G F++ G + L
Sbjct: 1335 VVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVGGADPEGT-FALDAASGRLYLARP 1393
Query: 2112 LDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGT 2171
LD E + V + + + V V V D N++ P FA+ + + EN G
Sbjct: 1394 LDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGA 1453
Query: 2172 DIIQVFAADGD-EGTNGQVRYGIVNGNTN-QEFRIDSVTGAITVAKPLDREKTPTYHLTV 2229
+ A+D D G N VRY ++ R+D+ TGA++ + LDRE TP L V
Sbjct: 1454 ALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLV 1513
Query: 2230 QATDR---GSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARD 2286
+ATDR S R + + + D ND PVF SP V +PE+ P L VVARD
Sbjct: 1514 EATDRPANASRRRAARVSARVFVTDENDNAPVFA-SPSRVRLPEDQPPGPAA-LHVVARD 1571
Query: 2287 DDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTG 2346
D G +++SY L G + + S++G L V + LDRE + VL + A+D GSP +
Sbjct: 1572 PDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSA 1631
Query: 2347 TGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNS 2406
T + V V DVND PTF + Y + E+ P GT +L + A+D D N + G +S
Sbjct: 1632 TQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTYGGVSS 1691
Query: 2407 Q-FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPR 2465
+ F+++P TG + T LDRE ++ L V D GSP L+ T V V V D ND+ P
Sbjct: 1692 ESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVT-VRVAVEDENDHAPT 1750
Query: 2466 FQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRNSEKFHIDPLRGAIMA 2524
F +P P + + +D D+G N +L Y L G S F +D G
Sbjct: 1751 FGSAHLSLEVPEGQDPQTLTM-LRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGT 1809
Query: 2525 AGPLNGASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKADF-PKVRAKEQTFMFPENQP 2581
PL+ E F + + +DGG + + +TV ++ D P + PE+ P
Sbjct: 1810 MRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVP 1869
Query: 2582 VSSLVTTITG----SSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVV 2637
+L+ + + G ++YY+ +G G F ++ +G++ + LD E+ Y
Sbjct: 1870 AGTLLLQLQAHDPDAGANGH-VTYYLGAGTAG-AFLLEPSSGELRTAAALDREQCPSYTF 1927
Query: 2638 WIEARDGGFP-PFSSYEKLDITVLDVNDNAPIFKEDPFISEILE-----NLSPRKILTVS 2691
+ A DG P S+ + ITV DVND+AP F P + + + T+
Sbjct: 1928 SVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLR 1987
Query: 2692 AMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVR------PLDREKVSHYVLTIKS 2745
A D+D+G N + Y + G +++ TGEIR R P DR VL I +
Sbjct: 1988 AEDRDAGANASILYRLA-GTPPPGTTVDSYTGEIRVARSPVALGPRDR------VLFIVA 2040
Query: 2746 SDKGSPSQSTSVKVMINILDENDNAPRFSQIFS-AHVPENSPLGYTVTRVTTSDEDIGIN 2804
+D G P++S + +++ + E + PRF + S A + EN+P G + G N
Sbjct: 2041 TDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTN 2099
Query: 2805 AISRYSIMDASLP--FTINPSTGDIVI--SRPLNREDTDRYRIRVSAHDSGWTVSTDVTI 2860
YSI+ + F+I PSTG I + + L+ E + R R+ + A G T +T+
Sbjct: 2100 GPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAFTVLTL 2159
Query: 2861 FVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE---Y 2917
+ D NDNAPRF R Y PE + + QV A D D+GS GQ+ Y + +
Sbjct: 2160 TLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGL 2219
Query: 2918 FRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSN 2977
F ++ TTG I IL + ++ ++DRG P+L+ T+T+ ++D+N
Sbjct: 2220 FHVDPTTGTITTTAILDREIWA--------ETRLVLMATDRGSPALVGSATLTVMVIDTN 2271
Query: 2978 DNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDND 3037
DN P + + V+++ +G+++ +VT +D D G + Y +S F +
Sbjct: 2272 DNRPT-IPQPWELRVSEDALLGSEIAQVTG-NDVDSG--PVLWYVLSPSGPQDPFSVGRY 2327
Query: 3038 TGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSAT 3097
G +S+ L + + + + A D P +A + + V + N + P FSQS
Sbjct: 2328 GGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVNDNAPAFSQSLYQVM 2384
Query: 3098 IPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTL---AKALDY 3154
+ E GS + +VSA DRD+ NG I Y ++S + F+++ + G L AL +
Sbjct: 2385 LLEHTPPGSAILSVSATDRDSGANGHISYHLASPADG--FSVDPNNGTLFTIVGTVALGH 2442
Query: 3155 ELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVI 3214
+ ++ + A D G R +V V + D ND++P F Y V E+ P G+T++
Sbjct: 2443 DGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLL 2502
Query: 3215 HLNATDAD-SGTNAVIAYTVQSSD-SDLFVIDPNT--------------GVITTQGFLDF 3258
L ATDAD S ++A + Y++ S + +F ++P G + LDF
Sbjct: 2503 TLEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDF 2562
Query: 3259 ETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVG 3318
E+ Y+LTV A + + S V + + N+ P F Y + E P G +
Sbjct: 2563 ESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELL 2622
Query: 3319 EVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNF 3378
V ASD D G G V + + F++++ +G + ++ LD E + R L V A +
Sbjct: 2623 HVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADP 2682
Query: 3379 GSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSW 3437
GA V + V D ND P F LN+ S ++E P GT VT + A D D+ ++
Sbjct: 2683 A---GAHFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDA-GAF 2738
Query: 3438 SRFSYFI---GSGNENG-AFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGS 3493
R Y + G G E AF++N TG++ D E + L V A D+G SA+ +
Sbjct: 2739 GRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVT 2798
Query: 3494 ASLLVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGP 3553
S+LVT ED D + +V E R G + +Q+TD D G L S
Sbjct: 2799 VSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDED----GGADGLVLYSLAT 2854
Query: 3554 ATSYFSLS-TAGVL 3566
++ YF ++ T G L
Sbjct: 2855 SSPYFGINQTTGAL 2868
Score = 879 bits (2270), Expect = 0.0
Identities = 769/2629 (29%), Positives = 1218/2629 (46%), Gaps = 208/2629 (7%)
Query: 1110 EEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM-----VQPDFELHAISGEITNTHQFDRE 1164
+EEQ AG+ +G +SA G + Y V D + SG + DRE
Sbjct: 52 DEEQPAGTLIGDISA-GLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDRE 110
Query: 1165 SLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMK--DINDNAPKFLKDFYQATISES 1222
R R TAV D ATV V ++ DIND+AP F + + E
Sbjct: 111 QRDRYRFTAV---------------TPDGATVEVTVRVADINDHAPAFPQARAALQVPEH 155
Query: 1223 AANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSG-------QVTLIGKLDY 1275
A T+ A D D G G Y++ F +++ G ++ + G+LD
Sbjct: 156 TAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDR 215
Query: 1276 EATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVS 1335
E Y L ++A D G+ P + L++ +LD ND+ P+F +S V E++ G V
Sbjct: 216 ENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVL 275
Query: 1336 SVTATDSDSGDNADLYYSITGTNNHGT--FSISPNTGSIFLAKKLDFETQSLYKLNITAK 1393
V A+D+D+G N + Y I + G FSI +TG + L + LDFE + +++L + A+
Sbjct: 276 QVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQAR 335
Query: 1394 DQGRPPRSSTMSVVIHVRDFNDNPPS----FPPGDIFKSIVENIPIGTSVISVTAHDPDA 1449
D G P + V +HVRD NDN PS F D + E P G V ++ DPD
Sbjct: 336 DGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPD- 394
Query: 1450 DINGQLSYTIIQQMPRGNHFTIDEVKGTIY---TNAEIDREFANLFELTVKANDQAVPIE 1506
+G ++ + HF + IY +DRE + + L V A D P
Sbjct: 395 --DGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPL 452
Query: 1507 TRRYALKNVTILVTDLNDNVPMFISQNALAADPS---AVIGSVLTTIMAADPDEGANGEI 1563
A + VTD+NDN P F Q +P A+ GS + + A DPD+G NG++
Sbjct: 453 RAEAAF---VLHVTDVNDNAPAFDRQ-LYRPEPLPEVALPGSFVVRVTARDPDQGTNGQV 508
Query: 1564 EYEIING-DTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
Y + G T F +D SG + A++L + LIV ATD G S+ +++ L
Sbjct: 509 TYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVAL 568
Query: 1622 QGLDG--PVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGR 1679
Q ++ P F + Y L EG GT + + A P S+ + G
Sbjct: 569 QDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATD--ADSGPFGLLSYSLGAGLGSSGS 626
Query: 1680 L-FTIGRHTGIIQTAAILDREQGACLYLVDVYAIE----KSTAFPRTQRAEVEITLQDIN 1734
F I H+G + T LDR+QG + V A++ KS + V++ L D N
Sbjct: 627 PPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVY-------VKVFLSDEN 679
Query: 1735 DNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPES 1793
DNPP F ++ G+ +++L A D D+G++ ++Y I++G + F +D +S
Sbjct: 680 DNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQS 739
Query: 1794 GDLIATRRLDRERRSKYSLLVRADDG--LQSS-DMRINITVSDVNDHTPKFSRPVYSFDI 1850
G L L R S L + A+DG LQ+ R++I++ P F + Y F +
Sbjct: 740 GLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSV 799
Query: 1851 PEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQ 1910
PED PG+ V + A + G +T ++ D G+F L+ ++G+ R LD E+
Sbjct: 800 PEDVAPGTSVGIVQA-HNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLG 858
Query: 1911 YYI-LTVRAEDG-GGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNV 1968
+ L VRA G F RV + DVNDN P F + L N G+ +
Sbjct: 859 PVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRA 918
Query: 1969 TDADDGINSQLTYSIASGDSLGQFTVDKN-GVLKVLKALDRESQSFYNLVVQVHDLPQIP 2027
D D G+NS++T+++ +G G FTVD G +++++ L + L ++ D P
Sbjct: 919 LDPDSGVNSRVTFTLLAGGG-GAFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPP 977
Query: 2028 ASRFTSTAQVSIILLDVNDN--PPTFLSPKLTY---IPENTPIDTVVFKAQATDPDSGPN 2082
TS ++ +++ DV P F SP TY +P T T V + QA PD GP
Sbjct: 978 R---TSHFRLRVVVQDVGTRGLAPRFNSP--TYRVDLPSGTTAGTQVLQVQAQAPDGGPI 1032
Query: 2083 SYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSST---E 2139
+Y + + F + G + + LDRE Y L V+A + L T
Sbjct: 1033 TY--HLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTAT 1090
Query: 2140 VVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVN-GNT 2198
V V +L+ N+++P ++ + + EN GT + +VFA D D G NG++ Y +
Sbjct: 1091 VRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSED 1150
Query: 2199 NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPV 2258
++ FRI TG +T + LDRE+ +Y L VQ D GS PR+ T TV + +LD+ND P
Sbjct: 1151 SKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPT 1210
Query: 2259 FELSPYS------VNVPENL--GTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL 2310
F + + + VP+ + GTL T+ A+D D G N + Y L G +
Sbjct: 1211 FLQASGAAGGGLPIQVPDRVPPGTLVTTLQ---AKDPDEGENGTILYTLTGPGSELFSLH 1267
Query: 2311 SASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIV----------DDVNDN 2360
SGEL L R + +VL ++A D GSP + + + V V D+ +
Sbjct: 1268 PHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAER 1327
Query: 2361 VPTFASKAYFT-TIPEDAPTGTDVLLVNASDADASKNAVIRIIGG---NSQFTINPSTGQ 2416
P T T E G+ + V A + ++GG F ++ ++G+
Sbjct: 1328 DPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVGGADPEGTFALDAASGR 1387
Query: 2417 IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIP 2476
+ + LD E + + V ++ G + V V V D N++ P F P +P
Sbjct: 1388 LYLARPLDFEAGPPWRALTVRAE-GPGGAGARLLRVQVQVQDENEHAPAFARDPLALALP 1446
Query: 2477 SPTLPGSFVFAVTVTDAD-IGPNSELHYSLSGRNSE--KFHIDPLRGAIMAAGPLNGASE 2533
PG+ ++ +DAD GPNS++ Y L + +D GA+ A L+ +
Sbjct: 1447 ENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETT 1506
Query: 2534 VTFSVHVKD-----GGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTT 2588
+ V+ S + + V ++ D V A PE+QP
Sbjct: 1507 PALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAALH 1566
Query: 2589 IT------GSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEAR 2642
+ G + R +SY +ASG G+ F++ TG +S+ +PLD E+ ++V+ + A
Sbjct: 1567 VVARDPDLGEAAR---VSYRLASGGDGH-FRLHSSTGALSVVRPLDREQRAEHVLTVVAS 1622
Query: 2643 DGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNG 2701
D G PP S+ + L ++V DVND AP F++ + + EN P +LT+ A D D G NG
Sbjct: 1623 DHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANG 1682
Query: 2702 QLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMI 2761
Q+ Y G SFS++ TG + ++R LDRE+ LT+ + D+GSP Q T V V +
Sbjct: 1683 QVTY---GGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRV 1739
Query: 2762 NILDENDNAPRFSQIFSAHVPENSPLGY---TVTRVTTSDEDIGINAISRYSIMDA--SL 2816
+ DEND+AP F SAH+ P G T+T + SD D+G N +Y I+D S
Sbjct: 1740 AVEDENDHAPTFG---SAHLSLEVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSG 1796
Query: 2817 PFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDINDNAPRFS 2873
F ++ ++G+ RPL+RE +++R+ A D G + + +T+ V D ND+AP F
Sbjct: 1797 AFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFP 1856
Query: 2874 RTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE-YFRINATTGEIFNKQI 2932
+Y ++ PE G+ + Q+ A DPD G+NG V Y++ + + F + ++GE+
Sbjct: 1857 VPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAA 1916
Query: 2933 LKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET-TVTINIVDSNDNAPQFLKSKYFTP 2991
L + ++ F V++ D +S T +VTI + D ND+AP F S
Sbjct: 1917 LDREQCPSYT--------FSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLR 1968
Query: 2992 VTK---NVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLI 3048
+ + + T + +D+D G N+ + Y ++ G +D+ TG I VA S +
Sbjct: 1969 LPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARSPV 2027
Query: 3049 SDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIV 3108
+ ++ + + A D G P S+ + + + E P F ++ ATI E+ G+ +
Sbjct: 2028 ALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPI 2087
Query: 3109 RTVSARDRDAA-MNGLIKYSISSGNEEGIFAINSSTGILTL--AKALDYELCQKHEMTIS 3165
VS R A NG I YSI SGNE+G F+I STG +T+ A+ LD+E+ + + +
Sbjct: 2088 --VSPRAVHAGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQ 2145
Query: 3166 AIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGT 3225
A GG A T +T+ + D NDN+P FL Y + E+ P ++ + A D D G+
Sbjct: 2146 AESGGAFAFT---VLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGS 2202
Query: 3226 NAVIAYTVQSSDS--DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFAT 3283
I+Y++ +S LF +DP TG ITT LD E L + A + AT
Sbjct: 2203 GGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSAT 2262
Query: 3284 VNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
+ + + TN+ P + + + +SE A G+ + +V +D D G + Y++ + +
Sbjct: 2263 LTVMVIDTNDNRPT-IPQPWELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQ 2319
Query: 3344 KGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PP 3402
F + + G++ ++G LD E+ +R L++LA + G + V V D ND P
Sbjct: 2320 DPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHD-----GPHEGRANLTVLVEDVNDNAP 2374
Query: 3403 IFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQ- 3461
F+ ++Y V + E P G+ + VSA D DS + SY + S + FS++P G
Sbjct: 2375 AFSQSLYQVMLLEHTPPGSAILSVSATDRDSGAN-GHISYHLASPADG--FSVDPNNGTL 2431
Query: 3462 --ITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM- 3518
I T L + ++ + A D G P A++ V L+D ND+ P T+S V
Sbjct: 2432 FTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAV 2491
Query: 3519 -ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLS---------------T 3562
E+ PG+ ++TL++TD D + Y ++S G F L
Sbjct: 2492 TEDLPPGSTLLTLEATDADGSRSHAAVDYSIIS-GNWGRVFQLEPRLAEAGESAGPGPRA 2550
Query: 3563 AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNP 3611
G L +D E + + L+V D G P SS V +TV+D NDNP
Sbjct: 2551 LGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNP 2599
Score = 808 bits (2087), Expect = 0.0
Identities = 727/2483 (29%), Positives = 1158/2483 (46%), Gaps = 164/2483 (6%)
Query: 1259 AIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKS 1318
AID SG V LD E Y D T+ + + + D ND+ P+FP++
Sbjct: 93 AIDEHSGVVRTARVLDREQRDRYRFTAVTPDGATVEVT------VRVADINDHAPAFPQA 146
Query: 1319 TLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG-------S 1371
+ V E+ G A D+D+G Y+++G TF + G
Sbjct: 147 RAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPE 206
Query: 1372 IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVE 1431
+ + +LD E +S Y L + A D G PPR + + + + D ND+ P+F + E
Sbjct: 207 LVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSE 266
Query: 1432 NIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH-FTIDEVKGTIYTNAEIDREFAN 1490
++ G+ V+ V A D DA +NG ++Y I ++ G+ F+ID G + +D E
Sbjct: 267 SLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRR 326
Query: 1491 LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVI------G 1544
+ EL V+A D E VT+ V D NDN P ++ L+AD S + G
Sbjct: 327 VHELVVQARDGGAHPEL---GSAFVTVHVRDANDNQPS-MTVIFLSADGSPQVSEAAPPG 382
Query: 1545 SVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASALV---PSQLIYNLIV 1601
++ I +DPD+G + + G+ + + S V A + YNL V
Sbjct: 383 QLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRV 442
Query: 1602 SATDLG--PERRKSTTELTIILQGLDGPVFTQPKYITI-LKEGEPIGTNVISIEAASP-R 1657
+ATD G P R ++ L + + P F + Y L E G+ V+ + A P +
Sbjct: 443 TATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQ 502
Query: 1658 GSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTA 1717
G+ V Y + F+I +GII TAA LD E L+ V A +
Sbjct: 503 GTNGQVTYSLAP-----GAHTHWFSIDPTSGIITTAASLDYELEPQPQLI-VVATDGGLP 556
Query: 1718 FPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTY 1777
P A V + LQD+NDN P F + ++ E G+ +Q+TA DAD G L++Y
Sbjct: 557 -PLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSY 615
Query: 1778 TIISGADDS----FRIDPESGDLIATRRLDRERR-SKYSLLVRA-DDGLQSSDMRINITV 1831
++ +G S FRID SGD+ TR LDR++ S + V A D G S + + + +
Sbjct: 616 SLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFL 675
Query: 1832 SDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFL 1891
SD ND+ P+F Y+ I + PG+ V + A D D G +G ++Y + + +F L
Sbjct: 676 SDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTL 735
Query: 1892 NPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFT--TIRVYFNILDVNDNPPIFSLNSY 1949
+ +G+ + L L + AEDGGG + RV +I+ PPIF Y
Sbjct: 736 DEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQY 795
Query: 1950 STSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDK-NGVLKVLKALDR 2008
S+ E++ G++V + + G + +T S++ GD G F++D +G+L+ L+ LDR
Sbjct: 796 VFSVPEDVAPGTSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDR 854
Query: 2009 ESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYI-PENTPIDT 2067
E L ++V +P + + A+V ++L DVNDN P F +P+ T + P NT T
Sbjct: 855 ELLGPV-LELEVRAGSGVPPA--FAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGT 911
Query: 2068 VVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVAT 2127
++ +A DPDSG NS + +TLL G F++ G VRL L + L + A
Sbjct: 912 PIYTLRALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHVRLMRPLGPSGGPAHELELEAR 971
Query: 2128 DKGQPSLSSSTEVVVMVLDINDNN--PIFAQALYKVEINENTLTGTDIIQVFAADGDEGT 2185
D G P +S + V+V D+ P F Y+V++ T GT ++QV A D
Sbjct: 972 DGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPD--- 1028
Query: 2186 NGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTP---RTDT 2242
G + Y + + F ++ +G + V LDRE Y L V A +T T
Sbjct: 1029 GGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGT 1088
Query: 2243 STVSIVLLDINDFVPVFELSPYSVNVPENL--GTLPRTILQVVARDDDRGSNSKLSYVLF 2300
+TV + +L+ N+ P P + V EN GT ++ +V A D D G N +L+Y L
Sbjct: 1089 ATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGT---SVGRVFATDRDSGPNGRLTYSLQ 1145
Query: 2301 GGNEDN-AFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVN 2358
+ED+ AF + +GE+ Q+LDRE + + L++ D GSP + TGT++V V D+N
Sbjct: 1146 QLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLN 1205
Query: 2359 DNVPTF------ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI--RIIG-GNSQFT 2409
DN PTF A +P+ P GT V + A D D +N I + G G+ F+
Sbjct: 1206 DNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFS 1265
Query: 2410 INPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTD---VNDNPPRF 2466
++P +G+++T+A L R + +Y L + D GSP P S+S +LV V + + PP
Sbjct: 1266 LHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSP-PRSASLQLLVQVLPSARLAEPPPDL 1324
Query: 2467 QHHPYVTHIP--------SPTLPGSFVFAVTVTD-ADIGPNSELHYSLSGRNSEK--FHI 2515
+P PGS + +V + A +G L Y+L G + F +
Sbjct: 1325 AERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGA---LTYTLVGGADPEGTFAL 1381
Query: 2516 DPLRGAIMAAGPLN---GASEVTFSVHVKD-GGSFPKTDSTTVTVRFVNKADFPKVRAKE 2571
D G + A PL+ G +V + GG+ + V V+ N+ P
Sbjct: 1382 DAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENE-HAPAFARDP 1440
Query: 2572 QTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGN-----TFQIDQLTGQVSISQP 2626
PEN + + T S G + + L ++D TG +S +
Sbjct: 1441 LALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRG 1500
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLD-----ITVLDVNDNAPIFKEDPFISEILEN 2681
LD E ++ +EA D P +S + + V D NDNAP+F P + E+
Sbjct: 1501 LDRETTPALLLLVEATDR--PANASRRRAARVSARVFVTDENDNAPVFAS-PSRVRLPED 1557
Query: 2682 LSPRKI-LTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYV 2740
P L V A D D G ++ Y + +G + F ++ +TG + VRPLDRE+ + +V
Sbjct: 1558 QPPGPAALHVVARDPDLGEAARVSYRLASGG-DGHFRLHSSTGALSVVRPLDREQRAEHV 1616
Query: 2741 LTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDE 2799
LT+ +SD GSP +S + + +++ D ND AP F Q +S + EN+P G ++ + +D
Sbjct: 1617 LTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDP 1676
Query: 2800 DIGINAISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVST 2856
D+G N Y + +S F+++P TG + R L+RE+ + + V A D G
Sbjct: 1677 DVGANGQVTYGGV-SSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHV 1735
Query: 2857 DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKS--Q 2914
V + V D ND+AP F L+ PE + +T + A+DPD G+NGQ+ Y I
Sbjct: 1736 TVRVAVEDENDHAPTFGSAHLSLEVPEGQD-PQTLTMLRASDPDVGANGQLQYRILDGDP 1794
Query: 2915 SEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV 2974
S F ++ +GE + L + F + + D G+P+L + +T+ ++
Sbjct: 1795 SGAFVLDLASGEFGTMRPLDREVEPAFQ--------LRIEARDGGQPALSATLLLTVTVL 1846
Query: 2975 DSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKL 3034
D+ND+AP F Y V ++V GT L+++ A D D G N V Y++ G F L
Sbjct: 1847 DANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQA-HDPDAGANGHVTYYLGAGT-AGAFLL 1904
Query: 3035 DNDTGWISVASSLISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTEENYHTPEFSQSH 3093
+ +G + A++L + ++ +V+A D PLS+ +V ITV + N H P F S
Sbjct: 1905 EPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSP 1964
Query: 3094 MSATIPE---SHSIGSI-VRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLA 3149
+ +P S S ++ + T+ A DRDA N I Y ++ G ++S TG + +A
Sbjct: 1965 LRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVA 2023
Query: 3150 KALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPS 3209
++ + + I A D G AR+ + V + + P F T+ ENAP
Sbjct: 2024 RSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPP 2083
Query: 3210 GTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQGF--LDFETKQSYHL 3266
GT ++ A A GTN I Y++ S ++ F I P+TG IT + LDFE L
Sbjct: 2084 GTPIVSPRAVHA-GGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRL 2142
Query: 3267 TVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRD 3326
++A +F + + L+ N+ PRF+ Y + E+ P + +V A D D
Sbjct: 2143 VLQA---ESGGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLD 2199
Query: 3327 LGTDGEVHYLIFGNSRKKG-FQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGAD 3385
G+ G++ Y + + +G F ++ TG I + ILDRE L ++A + GS A
Sbjct: 2200 QGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGS--PAL 2257
Query: 3386 IDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPS-WSRFSYFI 3444
+ T+ V V+D ND + +++SE +G+ + V+ D DS P W Y +
Sbjct: 2258 VGSATLTVMVIDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLW----YVL 2313
Query: 3445 GSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDIN 3504
FS+ G++++T LD E Y L +LA D G A+L V +ED+N
Sbjct: 2314 SPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVN 2370
Query: 3505 DNGPMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST 3562
DN P + S +VM E+ PG+ ++++ +TD D N G +Y+L S PA +
Sbjct: 2371 DNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGAN-GHISYHLAS--PADGFSVDPN 2427
Query: 3563 AGVLST---TREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEI 3619
G L T T + + + + +D G P ++ TVH+ + DQND+
Sbjct: 2428 NGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHY 2487
Query: 3620 FVNYYGNLFPGGILGSVKPQDPD 3642
V +L PG L +++ D D
Sbjct: 2488 RVAVTEDLPPGSTLLTLEATDAD 2510
Score = 781 bits (2016), Expect = 0.0
Identities = 703/2438 (28%), Positives = 1092/2438 (44%), Gaps = 177/2438 (7%)
Query: 1319 TLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGT---FSISPNTGSIFLA 1375
+L + + E G L+ ++A +G A L Y I+ G +I ++G + A
Sbjct: 46 SLDLQIDEEQPAGTLIGDISA-GLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTA 104
Query: 1376 KKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI 1435
+ LD E + Y+ D +T+ V + V D ND+ P+FP + E+
Sbjct: 105 RVLDREQRDRYRFTAVTPD------GATVEVTVRVADINDHAPAFPQARAALQVPEHTAF 158
Query: 1436 GTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGT-------IYTNAEIDREF 1488
GT A D DA G Y + G F ++ G + E+DRE
Sbjct: 159 GTRYPLEPARDADAGRLGTQGYALSGD-GAGETFRLETRPGPDGTPVPELVVTGELDREN 217
Query: 1489 ANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI-SQNALAADPSAVIGSVL 1547
+ + L ++A D P R AL +VT+L D+ND+ P F S+ S GS +
Sbjct: 218 RSHYMLQLEAYDGGSP-PRRAQALLDVTLL--DINDHAPAFNQSRYHAVVSESLAPGSPV 274
Query: 1548 TTIMAADPDEGANGEIEYEIINGDTD---TFIVDRYSGDLRVASAL-VPSQLIYNLIVSA 1603
+ A+D D G NG + YEI ++ F +D ++G L++ L + ++ L+V A
Sbjct: 275 LQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQA 334
Query: 1604 TDLGPERRKSTTELTIILQGLDGPVFTQPKYITI---------LKEGEPIGTNVISIEAA 1654
D G + +T+ ++ + QP I + E P G V I +
Sbjct: 335 RDGGAHPELGSAFVTVHVRDAND---NQPSMTVIFLSADGSPQVSEAAPPGQLVARISVS 391
Query: 1655 SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAI---LDREQGACLYLVDVYA 1711
P + + VS+ E F + +I + LDRE+ Y + V A
Sbjct: 392 DP--DDGDFAHVNVSLEGGEGH----FALSTQDSVIYLVCVARRLDREERDA-YNLRVTA 444
Query: 1712 IEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML-DLTVEENIGDGSKIMQLTAMDADEG 1770
+ + R + A V + + D+NDN P F + + E GS ++++TA D D+G
Sbjct: 445 TDSGSPPLRAEAAFV-LHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQG 503
Query: 1771 ANALVTYTIISGADDS-FRIDPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMR 1826
N VTY++ GA F IDP SG + LD E + L+V A DG +S
Sbjct: 504 TNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSAT 563
Query: 1827 INITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE---D 1883
+++ + DVND+ P+F R Y+ +PE T PG+ + ATD DSG G ++Y +
Sbjct: 564 VSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGS 623
Query: 1884 DEDGIFFLNPITGVFNLTRLLDYEV-QQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPP 1942
F ++ +G TR LD + + TV A DGGG + + V + D NDNPP
Sbjct: 624 SGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPP 683
Query: 1943 IFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDK-NGVLK 2001
F Y+ S+ P G+ VL D D G + +L+Y I +G+S FT+D+ +G+L
Sbjct: 684 QFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLT 743
Query: 2002 VLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IP 2060
V L R + S L + D + A +A+V I ++ PP F + + +P
Sbjct: 744 VAWPLARRANSVVQLEIGAEDGGGLQAE---PSARVDISIVPGTPTPPIFEQLQYVFSVP 800
Query: 2061 ENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEV 2117
E+ T V QA +P P TL G+ FS+ + G ++ LDRE +
Sbjct: 801 EDVAPGTSVGIVQAHNP---PGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELL 857
Query: 2118 SNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVF 2177
V G P + V V++ D+NDN+P F V + NT GT I +
Sbjct: 858 GPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLR 917
Query: 2178 AADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGST 2237
A D D G N +V + ++ G F +D TG + + +PL P + L ++A D GS
Sbjct: 918 ALDPDSGVNSRVTFTLLAGGGGA-FTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSP 976
Query: 2238 PRTDTSTVSIVLLDIND--FVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKL 2295
PRT + +V+ D+ P F Y V++P T +LQV A+ D G +
Sbjct: 977 PRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGT-TAGTQVLQVQAQAPDGGP---I 1032
Query: 2296 SYVLFGGNEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPAL---TGTGTIN 2351
+Y L + F L SG L V +LDRE +E ++L + A L TGT T+
Sbjct: 1033 TYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVR 1092
Query: 2352 VIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI-----RIIGGNS 2406
V + + N++ P + F + E+ P GT V V A+D D+ N + ++ +
Sbjct: 1093 VSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSK 1152
Query: 2407 QFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRF 2466
F I+P TG++ T LDRE + +Y L+V D GSP P S++ +V V V D+NDN P F
Sbjct: 1153 AFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSP-PRSTTGTVHVAVLDLNDNSPTF 1211
Query: 2467 QHHPYVT------HIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRG 2520
+P PG+ V + D D G N + Y+L+G SE F + P G
Sbjct: 1212 LQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHSG 1271
Query: 2521 AIMAAGPLNGASE----VTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMF 2576
++ A PL A +T S H D GS P++ S + V+ + P R E
Sbjct: 1272 ELLTAAPLIRAERPHYVLTLSAH--DQGSPPRSASLQLLVQVL-----PSARLAEPPPDL 1324
Query: 2577 PENQPVSSLVTTITGSSLRG-------------EP-----MSYYIASG-NLGNTFQIDQL 2617
E P + + +T ++ G EP ++Y + G + TF +D
Sbjct: 1325 AERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLVGGADPEGTFALDAA 1384
Query: 2618 TGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISE 2677
+G++ +++PLDFE + +G + ++ + V D N++AP F DP
Sbjct: 1385 SGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDPLALA 1444
Query: 2678 ILENLSPRKIL-TVSAMDKDS-GPNGQLDYEIVNGNME-NSFSINHATGEIRSVRPLDRE 2734
+ EN P L T A D D GPN + Y ++ + ++ TG + + R LDRE
Sbjct: 1445 LPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRE 1504
Query: 2735 KVSHYVLTIKSSDK---GSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTV 2791
+L ++++D+ S ++ V + + DENDNAP F+ +PE+ P G
Sbjct: 1505 TTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAA 1564
Query: 2792 TRVTTSDEDIGINAISRYSIMDASLP-FTINPSTGDIVISRPLNREDTDRYRIRVSAHDS 2850
V D D+G A Y + F ++ STG + + RPL+RE + + V A D
Sbjct: 1565 LHVVARDPDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDH 1624
Query: 2851 GW---TVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQV 2907
G + + +T+ V D+ND AP F + Y + E G+ + + ATDPD G+NGQV
Sbjct: 1625 GSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQV 1684
Query: 2908 FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET 2967
Y S SE F ++ TG + + L + +N+ V + DRG P ++
Sbjct: 1685 TYGGVS-SESFSLDPDTGVLTTLRALDREEQ---EEINLT-----VYAQDRGSPPQLTHV 1735
Query: 2968 TVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDN 3027
TV + + D ND+AP F + V + T + + D D G N +++Y I + +
Sbjct: 1736 TVRVAVEDENDHAPTFGSAHLSLEVPEGQDPQT--LTMLRASDPDVGANGQLQYRILDGD 1793
Query: 3028 HLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTP 3087
G F LD +G L ++ F + + A+D G P LS+ + +TV + N H P
Sbjct: 1794 PSGAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAP 1853
Query: 3088 EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILT 3147
F S +PE G+++ + A D DA NG + Y + +G G F + S+G L
Sbjct: 1854 AFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTA-GAFLLEPSSGELR 1912
Query: 3148 LAKALDYELCQKHEMTISAIDG---GWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
A ALD E C + ++SA+DG G ++ T SVT+ V DVND++P F + +
Sbjct: 1913 TAAALDREQCPSYTFSVSAVDGAAAGPLSTT--VSVTITVRDVNDHAPTFPTSPLRLRLP 1970
Query: 3205 ENAPSGTT----VIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFET 3260
PS +T + L A D D+G NA I Y + + +D TG I
Sbjct: 1971 RPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALG 2030
Query: 3261 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 3320
+ L + A ++ R + + + L+G E PRF I E AP GT +
Sbjct: 2031 PRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSP 2090
Query: 3321 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNF 3378
A GT+G + Y I + K F I TG I V LD E R+ L + A++
Sbjct: 2091 RAVHAG-GTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESG 2149
Query: 3379 GSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSW 3437
G+ + +T+ DAND P F Y + E P+ + V A D D S
Sbjct: 2150 GAFAFT-----VLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQ-GSG 2203
Query: 3438 SRFSYFIGSGNE-NGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASL 3496
+ SY + + G F ++P TG IT TA LDRE L ++A D G+P+ GSA+L
Sbjct: 2204 GQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATL 2263
Query: 3497 LVTLEDINDNGPMLTVS-EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLS-TGPA 3554
V + D NDN P + E V E+ G+ + + D D GP +Y+LS +GP
Sbjct: 2264 TVMVIDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVD----SGPVLWYVLSPSGPQ 2319
Query: 3555 TSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVI--DQNDNPS 3612
+ G +S T +D EQ + L ++ D G ++TV+ D NDN
Sbjct: 2320 DPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG-----PHEGRANLTVLVEDVNDNAP 2374
Query: 3613 QSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCS 3650
V + PG + SV D D + H S
Sbjct: 2375 AFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHIS 2412
Score = 502 bits (1292), Expect = e-141
Identities = 476/1669 (28%), Positives = 738/1669 (44%), Gaps = 105/1669 (6%)
Query: 2093 LGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNP 2152
+G +I G VR LDRE+ Y T V D ++ EV V V DIND+ P
Sbjct: 88 VGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPD------GATVEVTVRVADINDHAP 141
Query: 2153 IFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGA-- 2210
F QA +++ E+T GT A D D G G Y + + FR+++ G
Sbjct: 142 AFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDG 201
Query: 2211 -----ITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYS 2265
+ V LDRE Y L ++A D GS PR + + + LLDIND P F S Y
Sbjct: 202 TPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYH 261
Query: 2266 VNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNE--DNAFTLSA-SGELGVTQSL 2322
V E+L +LQV A D D G N ++Y + D F++ A +G L + + L
Sbjct: 262 AVVSESLAP-GSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPL 320
Query: 2323 DRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPT----FASKAYFTTIPEDAP 2378
D E + L++ A D G+ G+ + V V D NDN P+ F S + E AP
Sbjct: 321 DFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAP 380
Query: 2379 TGTDVLLVNASDADASKNAVIRII--GGNSQFTINPSTGQIITSAL---LDRETKDNYTL 2433
G V ++ SD D A + + GG F ++ I + LDRE +D Y L
Sbjct: 381 PGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNL 440
Query: 2434 VVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTH-IPSPTLPGSFVFAVTVTD 2492
V +D+GSP PL + + ++ VTDVNDN P F Y +P LPGSFV VT D
Sbjct: 441 RVTATDSGSP-PLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARD 499
Query: 2493 ADIGPNSELHYSLS-GRNSEKFHIDPLRGAIMAAGPLNGASEVT--FSVHVKDGGSFPKT 2549
D G N ++ YSL+ G ++ F IDP G I A L+ E V DGG P
Sbjct: 500 PDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLA 559
Query: 2550 DSTTVTVRFVNKADF-PKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEP---MSYYIAS 2605
S TV+V + D P+ + PE + +T + P +SY + +
Sbjct: 560 SSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGA 619
Query: 2606 GNLGNT----FQIDQLTGQVSISQPLDFEK-IQKYVVWIEARDGGFPPFSSYEKLDITVL 2660
G LG++ F+ID +G V ++ LD ++ + + A DGG Y K+ ++
Sbjct: 620 G-LGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLS-- 676
Query: 2661 DVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSIN 2719
D NDN P F + + I P +L + A D D G +G+L Y I+ GN F+++
Sbjct: 677 DENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLD 736
Query: 2720 HATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQI-FS 2778
+G + PL R S L I + D G S +V I+I+ P F Q+ +
Sbjct: 737 EQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYV 796
Query: 2779 AHVPENSPLGYTVTRVTTSDEDIGINAIS-RYSIMDASLPFTINPSTGDIVISRPLNRE- 2836
VPE+ G +V V + + ++ S D F+++ +G + RPL+RE
Sbjct: 797 FSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDREL 856
Query: 2837 --DTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQV 2894
+R + V + + D+NDN+P F + P T G+ + +
Sbjct: 857 LGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTL 916
Query: 2895 FATDPDEGSNGQV-FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIV 2953
A DPD G N +V F + F ++ TTG + ++++ +G H +
Sbjct: 917 RALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHV---RLMRPLGPSGGP-----AHELEL 968
Query: 2954 TSSDRGKPSLISE--TTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDK 3011
+ D G P S V + V + AP+F Y + GT++++V A
Sbjct: 969 EARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQA-QAP 1027
Query: 3012 DFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSS 3071
D G + Y ++ + F L+ +GW+ V ++L + + + + V A L
Sbjct: 1028 DGG---PITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQ 1084
Query: 3072 Q---ATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSI 3128
Q ATV +++ +N H+P S+ + E+ G+ V V A DRD+ NG + YS+
Sbjct: 1085 QTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSL 1144
Query: 3129 SSGNEEG-IFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDV 3187
+E+ F I+ TG +T + LD E +++ + DGG R+ +V V V+D+
Sbjct: 1145 QQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDL 1204
Query: 3188 NDNSPVFLSDDYFP------TVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLF 3241
NDNSP FL V + P GT V L A D D G N I YT+ S+LF
Sbjct: 1205 NDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSELF 1264
Query: 3242 VIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTN---EYVPRF 3298
+ P++G + T L + Y LT+ A + R + + +Q+ + E P
Sbjct: 1265 SLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDL 1324
Query: 3299 VSK--------LYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
+ + +E G+++G V A+ G + L+ G + F ++
Sbjct: 1325 AERDPAAPVPVVLTVTAAEGLRPGSLLGSV-AAPEPAGVGALTYTLVGGADPEGTFALDA 1383
Query: 3351 KTGQIYVSGILDREKEERV-SLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNI 3408
+G++Y++ LD E +L V A+ G GA + V V V D N+ P F +
Sbjct: 1384 ASGRLYLARPLDFEAGPPWRALTVRAEGPG---GAGARLLRVQVQVQDENEHAPAFARDP 1440
Query: 3409 YSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY-FIGSGNENGAFSINPQTGQITVTAE 3467
++ + E G + A D+D S Y + A ++ +TG ++
Sbjct: 1441 LALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRG 1500
Query: 3468 LDRETLPIYNLSVLAVD-----SGTPSATGSASLLVTLEDINDNGPML-TVSEGEVMENK 3521
LDRET P L V A D S +A SA + VT D NDN P+ + S + E++
Sbjct: 1501 LDRETTPALLLLVEATDRPANASRRRAARVSARVFVT--DENDNAPVFASPSRVRLPEDQ 1558
Query: 3522 RPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFY 3581
PG + + + DPDL + Y L++G + S+ G LS R +DREQ A+
Sbjct: 1559 PPGPAALHVVARDPDL--GEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHV 1616
Query: 3582 LSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDP 3641
L+VV D G P S+T + ++V D ND + E V N PG L +++ DP
Sbjct: 1617 LTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDP 1676
Query: 3642 DVLDSFHCSLTSGVTSLFSI---PGGTCDLNSQPRSTDGTFDLTVLSND 3687
DV + + + FS+ G L + R +LTV + D
Sbjct: 1677 DVGANGQVTYGGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQD 1725
Score = 172 bits (435), Expect = 1e-41
Identities = 153/542 (28%), Positives = 237/542 (43%), Gaps = 58/542 (10%)
Query: 51 VLEEQPPGTLVGTIQTRPG-------FTYRLSESHALFAINSSTGALYT-TSTIDRESLP 102
+LE PPG+ + ++ +Y L+ F+++ + G L+T T+
Sbjct: 2385 LLEHTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDG 2444
Query: 103 SDVINLVVLSSAPTYP-----TEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILD 157
S +++V+ + P V V ++D ND+AP F V ED G ++
Sbjct: 2445 SGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTL 2504
Query: 158 TATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGA------FLHLVSKGGLDRE 211
ATD+D GS Y II GN F+L+ L +GE A LV LD E
Sbjct: 2505 EATDAD-GSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFE 2563
Query: 212 VTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQ 271
QY L V D+G+P + + V VTV D+NDNPPVF + Y+ VPED VG+ +L
Sbjct: 2564 SLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLH 2623
Query: 272 VAAADADEGTNADIRYRLQ--DEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRG 329
V A+DAD G + +R+ + D F++D +G + + LD E + ++ L VQA D
Sbjct: 2624 VEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPA 2683
Query: 330 VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPA 389
A I++ DVND+ P FP SV EN GT+V L D D+
Sbjct: 2684 GAHF-ALAPVTIEVQDVNDHGPA-----FPLNLLSTSVAENQPPGTLVTTLHAIDGDA-G 2736
Query: 390 ANGNISVQIL----GGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYG 445
A G + +L G + F + SS ++ D E S+ L V +D
Sbjct: 2737 AFGRLRYSLLEAGPGPEGREAFALNSS----TGELRARVPFDYEHTESFRLLVGAAD--- 2789
Query: 446 APPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSG 505
S+ ++ + V +++ PVF + + E A G + + ATD D G
Sbjct: 2790 ------AGNLSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGG 2843
Query: 506 LNANLRYSIVSGN---------GLGWFHISEH---SGLVTTGSSGGLDRELASQIVLNIS 553
+ + YS+ + + G + + SG T+G G RE ++ L +
Sbjct: 2844 ADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVI 2903
Query: 554 AR 555
AR
Sbjct: 2904 AR 2905
Score = 35.8 bits (81), Expect = 1.1
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 27/141 (19%)
Query: 3473 LPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTLQS 3532
LP+ L +L + +G P A G A L + ++ E + GTL+ + +
Sbjct: 23 LPLLLLLLLLLGAGVPGAWGQAGSL----------------DLQIDEEQPAGTLIGDISA 66
Query: 3533 TDPDLPPNQGPFTYYLLS---TGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDS 3589
P P Y++ + +G T +GV+ T R +DREQ + + VT D
Sbjct: 67 GLP--AGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPD- 123
Query: 3590 GVPQMSSTGTVHITVIDQNDN 3610
+T V + V D ND+
Sbjct: 124 -----GATVEVTVRVADINDH 139
Score = 35.4 bits (80), Expect = 1.4
Identities = 14/32 (43%), Positives = 21/32 (65%)
Query: 4926 GTFNWDNLLNWGPGFGHYVDVFKDLASLPEKA 4957
G++NWD LL+W P F VF ++A L ++A
Sbjct: 3159 GSYNWDYLLSWCPQFQPLASVFTEIARLKDEA 3190
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 1070 bits (2766), Expect = 0.0
Identities = 935/3280 (28%), Positives = 1498/3280 (45%), Gaps = 253/3280 (7%)
Query: 187 LDITLNPSGEGAFLHLVSKGGL-------DREVTPQYQLLVEVEDKGEPKRRGYLQVNVT 239
L L PS E L ++ GL D YQL + P + + V +
Sbjct: 393 LQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTS----PGQASTVVV-ID 447
Query: 240 VQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD-EGTPFQM 298
+ D N++ P+F S Y + E+ G+SVL V A D D G N + Y + + PF +
Sbjct: 448 IVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALPFSI 507
Query: 299 DPETGLITVREPLDFEA-RRQYSLTVQAMDRGVPSLTGRAEAL-IQLLDVNDNDPVVKFR 356
DP G+I+ +P+D+E +R Y+ V+A D G P + ++ +QL ++NDN P+
Sbjct: 508 DPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPM---- 563
Query: 357 YFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPN 416
F + S+ ++ VG + ++ D D N+ +I+ GNE +F++
Sbjct: 564 -FEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQ---NLKYEIVSGNELEYFDLNHFSGV- 618
Query: 417 LSLIKVASALDRERIPSYNLTVSVSD--NYGAPP---------------------GAAVQ 453
+SL + L + SY+L ++ SD NY +P G Q
Sbjct: 619 ISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQ 678
Query: 454 ARSSVASLVIFVNDINDHPPVFSQQVYRVN---------------LSEEAPPGSYVSGIS 498
++ + N + S Y++N + E P + ++ ++
Sbjct: 679 FTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLA 738
Query: 499 ATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQG 558
ATD D+G N L Y I GN G F I +GL+T + LD E + +LN++ D G
Sbjct: 739 ATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAP--LDYEATNFYILNVTVYDLG 796
Query: 559 VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV 618
K S+ L V + D ND P F P GY +++ E+ GT + L D D DNG V
Sbjct: 797 TPQKSSWKLLTVNVKDWNDNAPRFP-PGGYQLTISEDTEVGTTIAELTTKDADSEDNGRV 855
Query: 619 RFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQS--SMARIN 676
R++L + F L P++G L LDRE + Y L V A D S S+ +
Sbjct: 856 RYTLL---SPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLI 912
Query: 677 VSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRF 736
++L D+NDNSP + E+ P G+ +T + A+DPDLG G V+Y + G F
Sbjct: 913 ITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTF 972
Query: 737 QVNAQSGVISTRMALDREEKTAYQLQIVATDGGN-LQSPNQAIVTITVLDTQDN--PPVF 793
+V+ +G + LD E + Y L + A+DGG L V + VLD +N PP F
Sbjct: 973 RVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHF 1032
Query: 794 SQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTTA 851
+ + V EN G V V+A D L+ + Y + G F+INQ TG + T
Sbjct: 1033 ASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTL 1092
Query: 852 NVIDREEQSFYQLKVVA-SGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQA 908
+DRE S+Y L V+A G+V + T V I V D NDN P QA+ ++ E+
Sbjct: 1093 APLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPV 1152
Query: 909 GHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD-VHAGSYQIEI 966
G S+ Q A DPD G + +++ N F I+ G +S LD + + +E+
Sbjct: 1153 GTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEV 1212
Query: 967 LASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSES-EPVN-SRFFKVQASDKD 1024
D G P L S+ + V + DVNDN P+F + V L E PV+ +++ ASD D
Sbjct: 1213 TVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLD 1272
Query: 1025 SGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRY-VLMVVASDRAVEPLSAT 1083
G NG + Y+I E + +AF I D + S Y +L + A+D PLSA+
Sbjct: 1273 EGLNGRVTYSI-EDSDEEAFSI--DLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSAS 1329
Query: 1084 VNVTVILEDVNDNRP-----LFNSTNYTFYFEEEQRAGSFVGKVSAVDKD----FGPNGE 1134
V + + E + RP F+ T Y+F E VG +S + F +G
Sbjct: 1330 VRLHI--EWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVEGRPGLFWFNISGG 1387
Query: 1135 VRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQA 1194
+ DF++ +G I D RRR ++ TV TD + A
Sbjct: 1388 DK------DMDFDIEKTTGSIVIARPLDT----RRRSN--YNLTVEVTDGS-----RTIA 1430
Query: 1195 T-VHVYM-KDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGL--IHYSII 1250
T VH++M +IN + P+FL+ Y+ + + ++LRV A D D+G + + IH S
Sbjct: 1431 TQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQD 1490
Query: 1251 KGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT-LNIDILDEN 1309
G+ F +D +SG + +GKLD + P+ + V IP+ + I + D N
Sbjct: 1491 PGSASL-FQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGN 1549
Query: 1310 DNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNT 1369
+ P F + V + + G + V A D+D G NA+++YS+ N+ G F+I+
Sbjct: 1550 LHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINALL 1609
Query: 1370 GSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSI 1429
G I LA+KLD + + L + A+DQG P +V+IHV + + P F + F I
Sbjct: 1610 GIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEI 1669
Query: 1430 VENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFA 1489
E+IP+G+ ++ V+A P +++Y + ++ + F+++ G I T ++D E
Sbjct: 1670 PESIPVGSPILLVSAMSPS-----EVTYEL-REGNKDGVFSMNSYSGLISTQKKLDHEKI 1723
Query: 1490 NLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAA-DPSAVIGSVLT 1548
+ ++L ++ ++ A + V + + D NDN PMF+ + +A + S++
Sbjct: 1724 SSYQLKIRGSNMA-----GAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIM 1778
Query: 1549 -------TIMAADPDEGANGEIEYEIINGDTDTFI-VDRYSGDLRVASAL-VPSQLIYNL 1599
I A+D D+ AN + Y+I+ + F +D G L + S + S +
Sbjct: 1779 DKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQF 1838
Query: 1600 IVSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYITILKEGEPIGTNVISIEAAS 1655
V D G + +I+ D P F++ Y + G ++ + A+
Sbjct: 1839 CVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASD 1898
Query: 1656 PRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKS 1715
++ V Y I + +E TI TG I A L L I S
Sbjct: 1899 ---EDSEVNYSIKTGNADEAV-----TIHPVTGSISVL------NPAFLGLSRKLTIRAS 1944
Query: 1716 TAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALV 1775
+ A V+I+L + D F D+ V+EN+ D ++ L A N +
Sbjct: 1945 DGLYQ-DTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQG--NHLNDTL 2001
Query: 1776 TYTIISGADDSFRIDPESGDLIATRRL--DRERRSKYSLLVRADDGLQSSDMR---INIT 1830
+Y +++G D + +S ++ TR + DRE++ + L V D + + ++
Sbjct: 2002 SYFLLNGTDMFHMV--QSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVS 2059
Query: 1831 VSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFF 1890
+ DVND+ PKF Y I + T PG ++ + ATD+D G NG +TY ED F
Sbjct: 2060 IEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYT--YFR 2117
Query: 1891 LNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYS 1950
++P G +L + DY+ Y L V A DGG + N + P+F Y
Sbjct: 2118 IDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYK 2177
Query: 1951 TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLKALDRE 2009
+ EN+ + + +L T A +L Y+I + L FT D K GVL V LD E
Sbjct: 2178 VRVPENITLYTPILH---TQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYE 2234
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLS-PKLTYIPENTPIDTV 2068
S++ + V+ D A S A V +++ DVNDNPPTF T I E P T
Sbjct: 2235 SKTKHVFTVRATDT----ALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTP 2290
Query: 2069 VFKAQATDPDSGPNSYIEYTLL---NPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVV 2125
V + A+D DSG N + Y ++ + + F I GE+ ELD E ++ + V
Sbjct: 2291 VIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVR 2350
Query: 2126 ATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGT 2185
A DKG P L+ T VVV V DINDN P F Q Y+ ++E G +++V A D D
Sbjct: 2351 AMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRD 2410
Query: 2186 NGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTPRTDT 2242
++ Y I++GN ++ F I+S +G I++ + +Y+L V A+D R + P
Sbjct: 2411 TSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVP---- 2466
Query: 2243 STVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGG 2302
V I + N + P F+ Y + EN + ++ ++A D D G + Y +
Sbjct: 2467 --VYINTTNANKYSPEFQQHLYEAELAEN-AMVGTKVIDLLAIDKDSGPYGTIDYTIINK 2523
Query: 2303 NEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVP 2362
F+++ +G++ Q LDRE V+ I T+ +I+ D NDN P
Sbjct: 2524 LASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPP 2583
Query: 2363 TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQFT-----INPSTGQI 2417
F + Y +I + + V+ V A DAD +NA + INP TG +
Sbjct: 2584 QFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVV 2643
Query: 2418 -ITSALLDRETKDNYTL-VVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHI 2475
+ +L+ E N TL + + G P +S V + V + P+F Y
Sbjct: 2644 KVKDSLVGLE---NQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSA 2700
Query: 2476 PSPTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEK-----FHIDPLRGAIMAAGPLN 2529
P GS + V A + YSL G E F +DP G I P++
Sbjct: 2701 PEDLPEGSEIGIVKAVAAQ----DPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMD 2756
Query: 2530 GASEVTFSVHVKDGGSFPKTD-----STTVTVRFVNKADFPKVRAKEQTFMFPENQPVSS 2584
S + + V TD S + V VN + P A + EN PV +
Sbjct: 2757 HESTKLYQIDVM-AHCLQNTDVVSLVSVNIQVGDVND-NRPVFEADPYKAVLTENMPVGT 2814
Query: 2585 LVTTITG---SSLRGEPMSYYIAS---GNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVW 2638
V +T + R +SY +++ N+ F ID +G ++ Q LD E Q Y
Sbjct: 2815 SVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFH 2874
Query: 2639 IEARDGGFP-PFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKIL-TVSAMDKD 2696
+ A D G SS + +++ D NDNAP F + + ++EN P +++ T+ +D D
Sbjct: 2875 VVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDAD 2934
Query: 2697 -SGPNGQLDYEIVNGNMENSFSINHATGE--IRSVRPLDREKVSHYVLTIKSSDKGSPSQ 2753
S N Q+ I G+ F I+ E I S + LDRE + Y+L + +SD
Sbjct: 2935 ISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDG---KF 2991
Query: 2754 STSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM 2812
SV V I +LD NDN+P+ SQ+ ++ V E+ G+ + +V+ +D D NA YS+
Sbjct: 2992 QASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLH 3051
Query: 2813 DASL-PFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTDINDNAP 2870
F ++P TG++ L+RE D + + A D G + D+T+ V D+NDNAP
Sbjct: 3052 GPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQADITLHVEDVNDNAP 3111
Query: 2871 RFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE-YFRINATTGEIFN 2929
RF + + + T + + V VFA DPD+G+N QV Y + +E +F I+ATTG I
Sbjct: 3112 RFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRL 3171
Query: 2930 KQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET-TVTINIVDSNDNAPQFLKSKY 2988
++ L+ + V +SD G P +S TVT+++V D P FL +++
Sbjct: 3172 EKPLQVRPQAPLE--------LTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEH 3223
Query: 2989 FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLI 3048
V ++ GT+++++ + + Y + + N G+F+LD TG + V +SL
Sbjct: 3224 SVQVPEDAPPGTEVLQLATLTRPGA---EKTGYRVVSGNEQGRFRLDARTGILYVNASLD 3280
Query: 3049 SDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIV 3108
+ + +F+++ K + LS TV + +T+ N H P+F Q S + E+ +G ++
Sbjct: 3281 FETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVI 3340
Query: 3109 RTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAID 3168
TVSA D D +N I YS+ GN+ G F I+ G L +AKALD E + + + A D
Sbjct: 3341 LTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATD 3400
Query: 3169 GGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNA- 3227
G + + V DVNDN P F +Y TV EN+P G+ V+ L +D DS N
Sbjct: 3401 SGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGP 3460
Query: 3228 -VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNI 3286
+ ++ F + P+ ++T +G L ++ Y L ++A + S +V +
Sbjct: 3461 PYSFRITKGNNGSAFRVTPDGWLVTAEG-LSRRAQEWYQLQIQASDSGIPPLSSLTSVRV 3519
Query: 3287 QLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRD 3326
+ + Y P + + + E +G +VG++ A+DRD
Sbjct: 3520 HVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRD 3559
Score = 1068 bits (2762), Expect = 0.0
Identities = 1061/3745 (28%), Positives = 1669/3745 (44%), Gaps = 333/3745 (8%)
Query: 174 YRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGG----LDREVTPQYQLLVEVEDKGEPK 229
YRII G+ A F+ + + G FL + +K L+REV Y L+++ +K +
Sbjct: 71 YRIISGDVANVFKTEEYV--VGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEK-TLE 127
Query: 230 RRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL 289
+V V + D ND P+F Y+ + ED + S + +V A DAD G NA+ Y
Sbjct: 128 LEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAF 187
Query: 290 QDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDN 349
F + P +G++TV L+ R ++ L V A+DR G + L V+
Sbjct: 188 NTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVE 247
Query: 350 DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
+ R PA + ++ GT A + V DA+S A SV+++GG+ +HF+
Sbjct: 248 PAL---RKPPAIASVVVTPPDSNDGTTYATVLV-DANSSGAEVE-SVEVVGGDPGKHFKA 302
Query: 410 QSS--KVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQAR------SSVASL 461
S + SL+ V E + +NL++ G+ P Q R S ++SL
Sbjct: 303 IKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARS--GSGPYFYSQIRGFHLPPSKLSSL 360
Query: 462 VIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLG 521
F + VYRV LSE +PPGS V + T NL+Y + +
Sbjct: 361 K------------FEKAVYRVQLSEFSPPGSRVVMVRVTPAFP----NLQYVLKPSSENV 404
Query: 522 WFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPV 581
F ++ +GL+TT Q+ + S P + +V+ ++D N+ P+
Sbjct: 405 GFKLNARTGLITTTKLMDFHDRAHYQLHIRTS-------PGQASTVVVIDIVDCNNHAPL 457
Query: 582 FSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRL 641
F++ YD ++ EN P GT +L + ATD D G+NG V +S+ A F +DP G +
Sbjct: 458 FNR-SSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI--AGPKALPFSIDPYLGII 514
Query: 642 STISSLDRE-EQAFYSLLVLATDLGSP-PQSSMARINVSLLDINDNSPVFYPVQYFAHIK 699
ST +D E + Y+ V A+D GSP + I + L ++NDN P+F V I+
Sbjct: 515 STSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIR 574
Query: 700 ENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSR-FQVNAQSGVISTR---MALDREE 755
++ P G I T+SA D D N +KY I +G+ F +N SGVIS + + L +
Sbjct: 575 QDWPVGKSIMTMSAIDVDELQN--LKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQ 632
Query: 756 KTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPV----------FSQVAYSFV---- 801
T+Y L+I A+DG N SP +T+ V D PV F++ F+
Sbjct: 633 PTSYSLKITASDGKNYASPTTLNITV-VKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQN 691
Query: 802 --------------------------------VFENVALGYHVGSVSASTMD--LNSNIS 827
V E+V + + ++A+ D N +
Sbjct: 692 QESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLV 751
Query: 828 YLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKV-VASGGTVTGDT--MVNITVK 884
Y+I G+++G F I TG LT A +D E +FY L V V GT + ++ + VK
Sbjct: 752 YVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVK 811
Query: 885 DLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINE 944
D NDN+P F + + E+ + G +I + D D NG V Y+L +P F+++
Sbjct: 812 DWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLL-SPTEKFSLHP 870
Query: 945 KNGTISLLGPLDVHAGS-YQIEILASDMGVP--QLSSSVILTVYVHDVNDNSPVFDQLSY 1001
G + + G LD + Y +++ A D QL S L + + DVNDNSP
Sbjct: 871 LTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHN 930
Query: 1002 EVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRE 1061
+ + E P + + ASD D G GE+ Y + +G G G L ++ ELD E
Sbjct: 931 RLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFE 990
Query: 1062 LQDRYVLMVVASDRAVEPLSATV--NVTVILEDVNDNR--PLFNSTNYTFYFEEEQRAGS 1117
+ Y L + ASD PL+ +V VI+ DVN+N P F S + +E +G+
Sbjct: 991 RRAGYNLSLWASDGG-RPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGT 1049
Query: 1118 FVGKVSAVDKDFGPNGEVRYSFEMVQ--PDFELHAISGEITNTHQFDRESLMRRRGTAVF 1175
V V+A D D G +GE++Y F ++ +G I DRE + +
Sbjct: 1050 QVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREF------ASYY 1103
Query: 1176 SFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSAS 1235
TV+A D+G PL V++ + D NDN P+ + + +I E A T VL++ A
Sbjct: 1104 WLTVLAVDRG-SVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAW 1162
Query: 1236 DVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPL 1295
D D + G + ++I GN F I +G ++ +LD E + L + +D+G L
Sbjct: 1163 DPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSL 1222
Query: 1296 NSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVT--------ATDSDSGDN 1347
ST + + ILD NDN P +F L N+R+ E +S V+ A+D D G N
Sbjct: 1223 KSTSRVVVGILDVNDNPP------IFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLN 1276
Query: 1348 ADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVV 1407
+ YSI ++ FSI TG + + F L I A D G+PP S+ SV
Sbjct: 1277 GRVTYSIEDSDEEA-FSIDLVTGVV--SSSSTFTAGEYNILTIKATDSGQPPLSA--SVR 1331
Query: 1408 IHVRDFNDNPPSFPP---GDIFKS--IVENIPIG--TSVISVTAHDPDADINGQLSYTII 1460
+H+ PS P + + S ++E P+ VISV L + I
Sbjct: 1332 LHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVEGRPG-------LFWFNI 1384
Query: 1461 QQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVT 1520
+ F I++ G+I +D + + LTV+ D + I T+ + ++
Sbjct: 1385 SGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIF-----MIA 1439
Query: 1521 DLNDNVPMFISQNALAADPSAVIGSV-LTTIMAADPDEGANGEIEYEIIN----GDTDTF 1575
++N + P F+ P + V L + A D D+G + + Y I G F
Sbjct: 1440 NINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKS--LIYTIHGSQDPGSASLF 1497
Query: 1576 IVDRYSGDLRVASALV----PSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQ 1631
+D SG L L PSQ ++V ++ +R + + L P FTQ
Sbjct: 1498 QLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQ 1557
Query: 1632 PKYITILKEGEPIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGII 1690
Y + + GT ++ + A + RG A V Y ++ E F I GII
Sbjct: 1558 LHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEG-----FFNINALLGII 1612
Query: 1691 QTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVE 1750
A LD+ A + + V A ++ + A V I + + + P+F + +
Sbjct: 1613 TLAQKLDQANHAP-HTLTVKAEDQGSP-QWHDLATVIIHVYPSDRSAPIFSKSEYFVEIP 1670
Query: 1751 ENIGDGSKIMQLTAMDADEGANALVTYTIISGADDS-FRIDPESGDLIATRRLDRERRSK 1809
E+I GS I+ ++AM E VTY + G D F ++ SG + ++LD E+ S
Sbjct: 1671 ESIPVGSPILLVSAMSPSE-----VTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISS 1725
Query: 1810 YSLLVRADDGLQS-SDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVA------- 1861
Y L +R + + +D+ + + + D ND+ P F + + I E S++
Sbjct: 1726 YQLKIRGSNMAGAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPF 1785
Query: 1862 AILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDG 1921
I A+D D N + Y + E + F ++P G + +DYE + V D
Sbjct: 1786 VIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQ 1845
Query: 1922 GGQFT----TIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINS 1977
G +V ++ DVND+PP FS Y +++ + G +L+ +D D +N
Sbjct: 1846 GSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSEVN- 1904
Query: 1978 QLTYSIASGDSLGQFTVDK-NGVLKVLK----ALDRESQSFYNLVVQVHDLPQIPASRFT 2032
YSI +G++ T+ G + VL L R+ L ++ D +
Sbjct: 1905 ---YSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRK------LTIRASD------GLYQ 1949
Query: 2033 STAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDT---VVFKAQATDPDSGPNSYIEYTL 2089
TA V I L V D F + D V+ AQ N + Y L
Sbjct: 1950 DTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHL----NDTLSYFL 2005
Query: 2090 LNPLGNKFSIGTIDGEVRLTG-ELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDIN 2148
LN + F + G ++ G DRE+ + L V D P + V V + D+N
Sbjct: 2006 LNGT-DMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVN 2064
Query: 2149 DNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVT 2208
DN P F Y I + T G + QV A D D GTNG V Y T FRID
Sbjct: 2065 DNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTY--FRIDPYL 2122
Query: 2209 GAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNV 2268
G I++ KP D + YHL V A D G TP + +V + N P+F+ Y V V
Sbjct: 2123 GDISLKKPFDYQALNKYHLKVIARD-GGTPSLQSEEEVLVTVR-NKSNPLFQSPYYKVRV 2180
Query: 2269 PENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGELGVTQSLDRETK 2327
PEN+ TL IL AR + +L Y + FT +G L VT LD E+K
Sbjct: 2181 PENI-TLYTPILHTQARSPE---GLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESK 2236
Query: 2328 ERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVN 2387
+ V + ATD+ + + T+ V+V+DVNDN PTF+ Y T+I E P T V+ +
Sbjct: 2237 TKHVFTVRATDTALGSFS-EATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLL 2295
Query: 2388 ASDADASKNAVI--RIIGGNSQ----FTINPSTGQIITSALLDRETKDNYTLVVVCSDAG 2441
ASD D+ +N + +I+ S F IN STG++ T LD E + ++ + V D G
Sbjct: 2296 ASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKG 2355
Query: 2442 SPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSEL 2501
P PL+ T V+V V+D+NDNPP F+ Y ++ G V V D D S L
Sbjct: 2356 DP-PLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRL 2414
Query: 2502 HYS-LSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVN 2560
Y LSG F I+ G I + ++++ V G+ TV V ++N
Sbjct: 2415 EYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRV---GASDGVFRATVPV-YIN 2470
Query: 2561 KADFPKVRAKEQTFMFP----ENQPVSSLVTTITGSSLRGEP---MSYYIASGNLGNTFQ 2613
+ K + Q ++ EN V + V + P + Y I + F
Sbjct: 2471 TTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFS 2530
Query: 2614 IDQLTGQVSISQPLDFEKIQKYVVWIE--ARDGGFPPFSSYEKLDITVLDVNDNAPIFKE 2671
I+ GQ++ Q LD E + V+ I+ ARDGG K+ +T D NDN P FK
Sbjct: 2531 INP-NGQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILT--DENDNPPQFKA 2587
Query: 2672 DPFISEILENLSPRK-ILTVSAMDKDSGPNGQLDYEIVNGNM-ENSFSINHATGEIR--- 2726
+ I N+S ++ V A D D G N + Y + ++ ++ IN TG ++
Sbjct: 2588 SEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKD 2647
Query: 2727 SVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ---IFSA--HV 2781
S+ L+ + + + IK+ D G P ++ V V + ++ + + P+FS+ FSA +
Sbjct: 2648 SLVGLENQTLDFF---IKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDL 2704
Query: 2782 PENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLP-------FTINPSTGDIVISRPLN 2834
PE S +G V V D I YS++ + P F+++P TG I + +P++
Sbjct: 2705 PEGSEIGI-VKAVAAQDPVI-------YSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMD 2756
Query: 2835 REDTDRYRIRVSAH---DSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKV 2891
E T Y+I V AH ++ V I V D+NDN P F Y E +G+ V
Sbjct: 2757 HESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSV 2816
Query: 2892 TQVFATDPDEGSNGQVFYFIKSQS-----EYFRINATTGEIFNKQILKYQNVTGFSNVNI 2946
QV A D D G +GQV Y + + E F I++ +G I Q L +
Sbjct: 2817 IQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETC-------- 2868
Query: 2947 NRHSFIVTSSDRGKP-SLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRV 3005
+ F V + D G+ L S+ V ++I D NDNAP+F +Y V +N + G + +
Sbjct: 2869 QTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATL 2928
Query: 3006 TAIDDKDFGLNSEVEYFISNDNHLGKFKLDN--DTGWISVASSLISDLNQNFFITVTAKD 3063
+D N +V +I+ + LG+F + D IS +L + + + VTA D
Sbjct: 2929 KTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASD 2988
Query: 3064 KGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGL 3123
+ TV I V + N ++P+ SQ + + E G + VSA D D N
Sbjct: 2989 G---KFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQ 3045
Query: 3124 IKYSISS-GNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTV 3182
I YS+ G E F ++ TG LT ALD E + A DGG R+ +T+
Sbjct: 3046 ITYSLHGPGAHE--FKLDPHTGELTTLTALDRERKDVFNLVAKATDGG--GRSCQADITL 3101
Query: 3183 NVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFV 3242
+V DVNDN+P F V +N T V + A D D G NA + Y++ S F
Sbjct: 3102 HVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFS 3161
Query: 3243 IDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCS-FATVNIQLKGTNEYVPRFVSK 3301
ID TGVI + L + LTV+A ++ S TV + + G +Y+P F++
Sbjct: 3162 IDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNT 3221
Query: 3302 LYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGIL 3361
+ ++ E AP GT V ++ R G + + ++ GN + + F+++ +TG +YV+ L
Sbjct: 3222 EHSVQVPEDAPPGTEVLQLATLTRP-GAEKTGYRVVSGNEQGR-FRLDARTGILYVNASL 3279
Query: 3362 DREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGT 3421
D E + L + S +D+ V VN+T ++ + P F + YS ++ E +G
Sbjct: 3280 DFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQ-FPQDPYSTRVLENALVGD 3338
Query: 3422 HVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVL 3481
+ VSA D D P S +Y + GN+ G F+I+P+ G++ V LDRE Y+L +
Sbjct: 3339 VILTVSATDEDG-PLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLR 3397
Query: 3482 AVDSGTPSATGSASLLVTLEDINDNGP---MLTVSEGEVMENKRPGTLVMTLQSTDPDLP 3538
A DSG P + + + D+NDN P L S V EN G+ V+ L +DPD P
Sbjct: 3398 ATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYST-TVQENSPIGSKVLQLILSDPDSP 3456
Query: 3539 PNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTG 3598
N P+++ + + G S F ++ G L T + R + L + DSG+P +SS
Sbjct: 3457 ENGPPYSFRI-TKGNNGSAFRVTPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLT 3515
Query: 3599 TVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTSGVT-- 3656
+V + V +Q+ + +EIF+ + F GG++G + D D D+ SL T
Sbjct: 3516 SVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLG 3575
Query: 3657 SLFSIPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLR 3716
FS+ + + G + V +DG +T T+ + V+ + ++ +
Sbjct: 3576 RHFSVGAPDGKIIAAQGLPRGHYSFNVTVSDGTFTT-TAGVHVYVWHVGQEALQQAMWMG 3634
Query: 3717 LGVPTVKDFLTNHYLHFLRIASSQL 3741
T ++ +++H+ + R S +L
Sbjct: 3635 FYQLTPEELVSDHWRNLQRFLSHKL 3659
Score = 1047 bits (2708), Expect = 0.0
Identities = 957/3347 (28%), Positives = 1546/3347 (46%), Gaps = 266/3347 (7%)
Query: 50 QVLEEQPPGTLVGTIQTRPGF-----TYRLSESHALFAINSSTGALYTTSTIDRESLPSD 104
Q+ E PPG+ V ++ P F + S + F +N+ TG + TT +D
Sbjct: 370 QLSEFSPPGSRVVMVRVTPAFPNLQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAH- 428
Query: 105 VINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDI 164
L + +S T V + + D N++AP+F S T E+ G V+ TATD D
Sbjct: 429 -YQLHIRTSPGQASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDH 487
Query: 165 GSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKG-GLDREVTPQ-YQLLVEV 222
G NG + +Y I AG L +++P +L ++S +D E+ + Y V
Sbjct: 488 GENG--YVTYSI-----AGPKALPFSIDP-----YLGIISTSKPMDYELMKRIYTFRVRA 535
Query: 223 EDKGEP-KRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGT 281
D G P +R + + + ++++NDN P+F + + +D VG S++ ++A D DE
Sbjct: 536 SDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQ 595
Query: 282 NADIRYRLQDEGTPFQMDPETGLITVREP---LDFEARRQYSLTVQAMDR---------- 328
N +E F ++ +G+I+++ P L YSL + A D
Sbjct: 596 NLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLN 655
Query: 329 --------------------------------GVPSLTGRAEALIQLLDVNDNDPVVKFR 356
G+ + E L N +F
Sbjct: 656 ITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFE 715
Query: 357 -YFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVP 415
+FP + V E+ + T +A L TD D+ NG + I GNE+ F+++
Sbjct: 716 DHFPQS---IDVLESVPINTPLARLAATDPDA-GFNGKLVYVIADGNEEGCFDIEL---- 767
Query: 416 NLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVF 475
L+ VA+ LD E Y L V+V D G P +SS L + V D ND+ P F
Sbjct: 768 ETGLLTVAAPLDYEATNFYILNVTVYD-LGTP------QKSSWKLLTVNVKDWNDNAPRF 820
Query: 476 SQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTG 535
Y++ +SE+ G+ ++ ++ D DS N +RY+++S H +VT
Sbjct: 821 PPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVT-- 878
Query: 536 SSGGLDRELASQIVLNISARDQGV--HPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVV 593
G LDRE + +L + ARDQ H S L++TL DVND P E + V
Sbjct: 879 --GHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQ-CITEHNRLKVP 935
Query: 594 ENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQA 653
E+ P GT L L A+D DLG G VR+ L + +FR+D ++G L LD E +A
Sbjct: 936 EDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGA--HGTFRVDLMTGALILERELDFERRA 993
Query: 654 FYSLLVLATDLGSP-PQSSMARINVSLLDINDN--SPVFYPVQYFAHIKENEPGGSYITT 710
Y+L + A+D G P + ++ + V +LD+N+N P F + ++EN P G+ +
Sbjct: 994 GYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIV 1053
Query: 711 VSATDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
V+A D D G +G ++Y + AG + F +N +G+I T LDRE + Y L ++A D G
Sbjct: 1054 VAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRG 1113
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNS--NIS 827
++ + V I V D DNPP SQ + + E+ +G V + A D +S ++
Sbjct: 1114 SVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLT 1173
Query: 828 YLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKV-VASGG--TVTGDTMVNITVK 884
+ IT+G+ G F I+ VTG L+TA +DRE + + L+V V G ++ + V + +
Sbjct: 1174 FNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGIL 1233
Query: 885 DLNDNSPHFLQAIESVNVVENWQ--AGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAI 942
D+NDN P F + +V + E + +++ A D DEG+NG V YS++ + + F+I
Sbjct: 1234 DVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSDEEAFSI 1293
Query: 943 NEKNGTISLLGPLDVHAGSYQI-EILASDMGVPQLSSSVILTVYVHDVNDNSPV---FDQ 998
+ G +S AG Y I I A+D G P LS+SV L + S + FD+
Sbjct: 1294 DLVTGVVSSSSTFT--AGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDE 1351
Query: 999 LSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI-FPDGQLYIKSE 1057
Y T+ E++PVN + G G + I+ G+ F I G + I
Sbjct: 1352 TYYSFTVMETDPVNHMVGVISV----EGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARP 1407
Query: 1058 LDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGS 1117
LD + Y L V +D + ++ V++ +I ++N +RP F T Y ++ G
Sbjct: 1408 LDTRRRSNYNLTVEVTDGS-RTIATQVHIFMI-ANINHHRPQFLETRYEVRVPQDTVPGV 1465
Query: 1118 FVGKVSAVDKDFGPNGEVRYSFEMVQPD-----FELHAISGEITNTHQFDRESLMRRRGT 1172
+ +V A+D+D G + + Y+ Q F+L SG + + D S G
Sbjct: 1466 ELLRVQAIDQDKGKS--LIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGS-----GP 1518
Query: 1173 AVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV 1232
+ + TV+ DQ IP ++ V ++++D N + P+F + Y+A++ ++ A T++L+V
Sbjct: 1519 SQHTLTVMVRDQEIPIK-RNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQV 1577
Query: 1233 SASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGT 1292
A D D G N +HYS++KGN E F I++ G +TL KLD ++L ++A D G+
Sbjct: 1578 RAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGS 1637
Query: 1293 IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYY 1352
+ T+ I + + + P F KS FV++ E++ +G + V+A +++ Y
Sbjct: 1638 PQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSP-----SEVTY 1692
Query: 1353 SITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
+ N G FS++ +G I KKLD E S Y+L I + + + VV+ + D
Sbjct: 1693 ELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMA--GAFTDVMVVVDIID 1750
Query: 1413 FNDNPPSFPPGDIFKSIVENIPIGTSVIS-------VTAHDPDADINGQLSYTIIQQMPR 1465
NDN P F I E P+ + ++ + A D D + N L Y I++
Sbjct: 1751 ENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEAL 1810
Query: 1466 GNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALK--NVTILVTDLN 1523
F ID GT+ +E+D E F+ V +DQ P+ +A + V I V D+N
Sbjct: 1811 -KFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPV---LFAPRPAQVIIHVRDVN 1866
Query: 1524 DNVPMFISQNALAADPSAV-IGSVLTTIMAADPDEGANGEIEYEIINGDTDTFI-VDRYS 1581
D+ P F Q A + G L + A+D D E+ Y I G+ D + + +
Sbjct: 1867 DSPPRFSEQIYEVAIVGPIHPGMELLMVRASDED----SEVNYSIKTGNADEAVTIHPVT 1922
Query: 1582 GDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPV-FTQPKYITILKE 1640
G + V + L L + A+D G + + +++ + Q LD + F Q Y +KE
Sbjct: 1923 GSISVLNPAFLG-LSRKLTIRASD-GLYQDTALVKIS-LTQVLDKSLQFDQDVYWAAVKE 1979
Query: 1641 GEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAI-LDRE 1699
+ I A + Y++++ +F + + G++QT + DRE
Sbjct: 1980 NLQ-DRKALVILGAQGNHLNDTLSYFLLNGT-------DMFHMVQSAGVLQTRGVAFDRE 2031
Query: 1700 QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKI 1759
Q L + + R + V ++++D+NDNPP F +++ G +
Sbjct: 2032 QQDTHEL--AVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVL 2089
Query: 1760 MQLTAMDADEGANALVTYTIISGADD--SFRIDPESGDLIATRRLDRERRSKYSLLVRAD 1817
Q++A D D G N VTY A+D FRIDP GD+ + D + +KY L V A
Sbjct: 2090 FQVSATDEDLGTNGAVTYEF---AEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIAR 2146
Query: 1818 DG----LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVN 1873
DG LQS + + V+ N P F P Y +PE+ +L IL T S
Sbjct: 2147 DGGTPSLQSEE---EVLVTVRNKSNPLFQSPYYKVRVPENI---TLYTPILHTQARSPEG 2200
Query: 1874 GEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-GQFTTIRVYF 1932
+ Y + E++ +F + TGV +T LDYE + ++ TVRA D G F+ V
Sbjct: 2201 LRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEV 2260
Query: 1933 NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIA-SGDSLGQ 1991
+ DVNDNPP FS Y+TS+ E LP + V+ +D D G N ++Y I G + +
Sbjct: 2261 LVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSK 2320
Query: 1992 F--TVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPP 2049
F G + ++ LD E+Q +++ V+ D P T V + + D+NDNPP
Sbjct: 2321 FFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPP---LTGETLVVVNVSDINDNPP 2377
Query: 2050 TFLSPKL-TYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDGE 2105
F P+ + E +V K QA DPDS S +EY +L+ GN+ F I + G
Sbjct: 2378 EFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILS--GNQDRHFFINSSSGI 2435
Query: 2106 VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINE 2165
+ + + S+Y L V A+D ++ V + + N +P F Q LY+ E+ E
Sbjct: 2436 ISMFNLCKKHLDSSYNLRVGASD---GVFRATVPVYINTTNANKYSPEFQQHLYEAELAE 2492
Query: 2166 NTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTY 2225
N + GT +I + A D D G G + Y I+N +++F I+ G I + LDRE +
Sbjct: 2493 NAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINP-NGQIATLQKLDRENSTER 2551
Query: 2226 HLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVAR 2285
+ ++ R R TV I+L D ND P F+ S Y+V++ N+ + ++QV+A
Sbjct: 2552 VIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNV-SKDSPVIQVLAY 2610
Query: 2286 DDDRGSNSKLSYVLFGGN--EDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPA 2343
D D G N+ ++Y + + +D +G + V SL + I A D G P
Sbjct: 2611 DADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPH 2670
Query: 2344 LTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIG 2403
+ + V ++P F+ Y + PED P G+++ +V A A + ++
Sbjct: 2671 WNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKA--VAAQDPVIYSLVR 2728
Query: 2404 GNSQ-------FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTV 2456
G + F+++P TG I +D E+ Y + V+ + + + S SV + V
Sbjct: 2729 GTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTD-VVSLVSVNIQV 2787
Query: 2457 TDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLS---GRN-SEK 2512
DVNDN P F+ PY + G+ V VT D D G + ++ Y LS G N E
Sbjct: 2788 GDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHEL 2847
Query: 2513 FHIDPLRGAIMAAGPLNGASEVTFSVHV---KDGGSFPKTDSTTVTVRFVNKAD-FPKVR 2568
F ID G I L+ + T+ HV G + + V V ++ D P+
Sbjct: 2848 FAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFA 2907
Query: 2569 AKEQTFMFPENQPVSSLVTTI----TGSSLRGEPMSYYIASGNLGNTFQIDQLTGQ--VS 2622
++E EN LV T+ S + ++ YI G+ F I Q+ + +S
Sbjct: 2908 SEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRIS 2967
Query: 2623 ISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENL 2682
+ LD E KY++ + A DG F + ++I VLDVNDN+P + + ++ E++
Sbjct: 2968 SRKTLDREHTAKYLLRVTASDG---KFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDV 3024
Query: 2683 SP-RKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVL 2741
P IL VSA D D+ N Q+ Y + +G + F ++ TGE+ ++ LDRE+ + L
Sbjct: 3025 FPGHFILKVSATDLDTDTNAQITYSL-HGPGAHEFKLDPHTGELTTLTALDRERKDVFNL 3083
Query: 2742 TIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAH----VPENSPLGYTVTRVTTS 2797
K++D G +S + +++ D NDNAPRF F +H V +N+ + V V
Sbjct: 3084 VAKATDGG--GRSCQADITLHVEDVNDNAPRF---FPSHCAVAVFDNTTVKTPVAVVFAR 3138
Query: 2798 DEDIGINAISRYSIMD-ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVST 2856
D D G NA YS+ D A F+I+ +TG I + +PL + V A D G +
Sbjct: 3139 DPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPL 3198
Query: 2857 D----VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFA-TDPDEGSNGQVFYFI 2911
VT+ V + D P F T + + PE G++V Q+ T P G Y +
Sbjct: 3199 STLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTG---YRV 3255
Query: 2912 KSQSEY--FRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTV 2969
S +E FR++A TG ++ L ++ ++ + S + SL TTV
Sbjct: 3256 VSGNEQGRFRLDARTGILYVNASLDFETSP--------KYFLSIECSRKSSSSLSDVTTV 3307
Query: 2970 TINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHL 3029
+NI D N++ PQF + Y T V +N VG ++ V+A D+ D LNS++ Y + N L
Sbjct: 3308 MVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDE-DGPLNSDITYSLIGGNQL 3366
Query: 3030 GKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 3089
G F + G + VA +L + ++ + + A D G PPL + I V + N + P F
Sbjct: 3367 GHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRF 3426
Query: 3090 SQSHMSATIPESHSIGSIVRTVSARDRDAAMNG-LIKYSISSGNEEGIFAINSSTGILTL 3148
Q + S T+ E+ IGS V + D D+ NG + I+ GN F + + G L
Sbjct: 3427 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRV-TPDGWLVT 3485
Query: 3149 AKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAP 3208
A+ L + +++ I A D G + SV V+V + + +P L + F TV E+
Sbjct: 3486 AEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEF 3545
Query: 3209 SGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVID-PNTGVITTQG 3254
G V ++ATD D + + + F + P+ +I QG
Sbjct: 3546 QGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQG 3592
Score = 989 bits (2557), Expect = 0.0
Identities = 987/3667 (26%), Positives = 1603/3667 (43%), Gaps = 306/3667 (8%)
Query: 93 TSTIDRESLPSDVINLVVLSSAPTYP----TEVRVLVRDLNDNAPVFPDPSIVVTFKEDS 148
T+ ++RE D L++ ++ T T V V + D ND P+F PS VT ED
Sbjct: 104 TALLNREV--RDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDM 161
Query: 149 SSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGL 208
+ TATD+D+G N + ++ + F + T L++ +G
Sbjct: 162 PLKSPICKVTATDADLGQNAEFYYAFN----TRSEMFAIHPTSGVVTVAGKLNVTWRGKH 217
Query: 209 DREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSS 268
+ +V ++ E G + V V+ PP S D ++
Sbjct: 218 ELQVLAVDRMRKISEGNGFGSLAALV---VHVEPALRKPPAIASVVVTPPDSNDGTTYAT 274
Query: 269 VLQVAAADADEGTNADIRYRLQDEGTPFQM------DPETGLITVREPLDFEARRQYSLT 322
VL A + E + ++ D G F+ E L++V++ E ++L+
Sbjct: 275 VLVDANSSGAEVESVEVVGG--DPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLS 332
Query: 323 VQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+QA P + + ++ A R + E + G+ V ++ V
Sbjct: 333 LQARSGSGPYFYSQIRGFHL-----PPSKLSSLKFEKAVYR-VQLSEFSPPGSRVVMVRV 386
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSD 442
T A N+ + +E F++ + LI +D Y L + S
Sbjct: 387 TPAFP-----NLQYVLKPSSENVGFKLNA----RTGLITTTKLMDFHDRAHYQLHIRTS- 436
Query: 443 NYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDG 502
PG A S+V +VI + D N+H P+F++ Y L E PPG+ V ++ATD
Sbjct: 437 -----PGQA----STV--VVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDR 485
Query: 503 DSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQI-VLNISARDQGV-H 560
D G N + YSI L F I + G+++T S +D EL +I + A D G
Sbjct: 486 DHGENGYVTYSIAGPKALP-FSIDPYLGIIST--SKPMDYELMKRIYTFRVRASDWGSPF 542
Query: 561 PKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRF 620
+ + + L ++ND +P+F + S+ ++ P G ++ + A D D N +++
Sbjct: 543 RREKEVSIFLQLRNLNDNQPMFEEVNCTG-SIRQDWPVGKSIMTMSAIDVDELQN--LKY 599
Query: 621 SLQEAETDRRSFRLDPVSGRLST---ISSLDREEQAFYSLLVLATD-------------- 663
+ + F L+ SG +S +L + YSL + A+D
Sbjct: 600 EIVSGN-ELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITV 658
Query: 664 ------------------------------LGSPPQSSMARINVSLLDINDNSPVF---Y 690
L + S ++S IN +P F +
Sbjct: 659 VKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHF 718
Query: 691 PVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSR-FQVNAQSGVISTRM 749
P + E+ P + + ++ATDPD G NG + Y I+ G+ F + ++G+++
Sbjct: 719 PQSI--DVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAA 776
Query: 750 ALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALG 809
LD E Y L + D G Q + ++T+ V D DN P F Y + E+ +G
Sbjct: 777 PLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVG 836
Query: 810 YHVGSVSASTMDLNSN--ISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVV 867
+ ++ D N + Y + + +K F+++ +TG+L +DRE + Y LKV
Sbjct: 837 TTIAELTTKDADSEDNGRVRYTLLSPTEK--FSLHPLTGELVVTGHLDRESEPRYILKVE 894
Query: 868 A-----SGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDE 922
A G + T + IT++D+NDNSP + + V E+ G + A DPD
Sbjct: 895 ARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDL 954
Query: 923 GVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHA-GSYQIEILASDMGVPQLSSSVI 981
G G V Y L F ++ G + L LD Y + + ASD G P ++
Sbjct: 955 GPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLC 1014
Query: 982 -LTVYVHDVNDN--SPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEG 1038
+ V V DVN+N P F ++ + E+ P ++ V A D DSG +GE+ Y + G
Sbjct: 1015 HVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAG 1074
Query: 1039 NTGDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNR 1097
AF I D G + + LDRE Y L V+A DR PLS+ V + + D NDN
Sbjct: 1075 TGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNP 1134
Query: 1098 PLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM--VQPDFELHAISGEI 1155
P + + +E+ G+ V ++ A D D G++ ++ F +H ++G +
Sbjct: 1135 PQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLL 1194
Query: 1156 TNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFY 1215
+ Q DRE+ + + TV+ D G P LK + V V + D+NDN P F +
Sbjct: 1195 STAQQLDREN----KDEHILEVTVL--DNGEPS-LKSTSRVVVGILDVNDNPPIFSHKLF 1247
Query: 1216 QATISESAANLTQ--VLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKL 1273
+ E + ++ V R+ ASD+DEG NG + YSI + ++E F+ID +G V+
Sbjct: 1248 NVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSI-EDSDEEAFSIDLVTGVVS--SSS 1304
Query: 1274 DYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILD--ENDNTP-SFPKSTLFVDVLENMRI 1330
+ A L I+A DSG PL+++ L+I+ + + P +F ++ V+E +
Sbjct: 1305 TFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPV 1364
Query: 1331 GELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNI 1390
+V ++ G +++I+G + F I TGSI +A+ LD +S Y L +
Sbjct: 1365 NHMVGVISV----EGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTV 1420
Query: 1391 TAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDAD 1450
D R +T + + + N + P F + ++ G ++ V A D D
Sbjct: 1421 EVTDGSRT--IATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDK- 1477
Query: 1451 INGQLSYTIIQQMPRGNH--FTIDEVKGTIYTNAEIDREFA-NLFELTVKANDQAVPIET 1507
L YTI G+ F +D G + T ++D + LTV DQ +PI+
Sbjct: 1478 -GKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIK- 1535
Query: 1508 RRYALKNVTILVTDLNDNVPMFISQNALAADPSAVI-GSVLTTIMAADPDEGANGEIEYE 1566
R + VTI V D N + P F + A+ P + G+ L + A D D G N E+ Y
Sbjct: 1536 RNFVW--VTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYS 1593
Query: 1567 IINGDTDTFI-VDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIILQGL 1624
++ G+++ F ++ G + +A L + + L V A D G + + I +
Sbjct: 1594 LLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPS 1653
Query: 1625 D--GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFT 1682
D P+F++ +Y + E P+G+ ++ + A SP SE V+ E +F+
Sbjct: 1654 DRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSP--SE-------VTYELREGNKDGVFS 1704
Query: 1683 IGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPT 1742
+ ++G+I T LD E+ + Y + + + AF V + + D NDN P+F
Sbjct: 1705 MNSYSGLISTQKKLDHEKISS-YQLKIRGSNMAGAFTDVM---VVVDIIDENDNAPMFLK 1760
Query: 1743 DMLDLTVEENIGDGSKIMQ-------LTAMDADEGANALVTYTIISG-ADDSFRIDPESG 1794
+ E S IM + A D+D+ AN+L+ Y I+ A F+IDP G
Sbjct: 1761 STFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMG 1820
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGLQSSDM-------RINITVSDVNDHTPKFSRPVYS 1847
L +D E + V D Q S + ++ I V DVND P+FS +Y
Sbjct: 1821 TLTIVSEMDYESMPSFQFCVYVHD--QGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYE 1878
Query: 1848 FDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYE 1907
I PG + + A+D+DS VN Y + + D ++P+TG ++
Sbjct: 1879 VAIVGPIHPGMELLMVRASDEDSEVN----YSIKTGNADEAVTIHPVTGSISVLNPAFLG 1934
Query: 1908 VQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFN 1967
+ + LT+RA DG Q T + V ++ V D F + Y ++ ENL +++
Sbjct: 1935 LSRK--LTIRASDGLYQDTAL-VKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILG 1991
Query: 1968 VTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLK-ALDRESQSFYNLVVQVHD--LP 2024
+ +N L+Y + +G + V GVL+ A DRE Q + L V+V D P
Sbjct: 1992 AQG--NHLNDTLSYFLLNGTDMFHM-VQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTP 2048
Query: 2025 QIPASRFTSTAQVSIILLDVNDNPPTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNS 2083
Q A V + + DVNDNPP F P T I + T V+F+ ATD D G N
Sbjct: 2049 QRVAQGL-----VRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNG 2103
Query: 2084 YIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVM 2143
+ Y F I G++ L D + ++ Y L V+A D G PSL S EV+V
Sbjct: 2104 AVTYEFAEDY-TYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVT 2162
Query: 2144 VLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFR 2203
V N +NP+F YKV + EN T I+ A EG ++ Y IV F
Sbjct: 2163 VR--NKSNPLFQSPYYKVRVPENITLYTPILHT-QARSPEGL--RLIYNIVEEEPLMLFT 2217
Query: 2204 IDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSP 2263
D TG +TV PLD E + TV+ATD ++ +TV +++ D+ND P F
Sbjct: 2218 TDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSE-ATVEVLVEDVNDNPPTFSQLV 2276
Query: 2264 YSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLF--GGNEDNAFTLSAS-GELGVTQ 2320
Y+ ++ E L ++Q++A D D G N +SY + G + F ++ S GE+ Q
Sbjct: 2277 YTTSISEGLPA-QTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQ 2335
Query: 2321 SLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTG 2380
LD E ++ F + + A D G P LTG + V V D+NDN P F Y + E A G
Sbjct: 2336 ELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCG 2395
Query: 2381 TDVLLVNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLDRETKDNYTLVVV 2436
VL V A D D+ + + I+ GN F IN S+G I L + +Y L V
Sbjct: 2396 HLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVG 2455
Query: 2437 CSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG 2496
SD ++ V + T+ N P FQ H Y + + G+ V + D D G
Sbjct: 2456 ASDG----VFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSG 2511
Query: 2497 PNSELHYSLSGR-NSEKFHIDPLRGAIMAAGPLNGASE----VTFSVHVKDGGSFPKTDS 2551
P + Y++ + SEKF I+P G I L+ + + V +DGG +
Sbjct: 2512 PYGTIDYTIINKLASEKFSINP-NGQIATLQKLDRENSTERVIAIKVMARDGGG--RVAF 2568
Query: 2552 TTVTVRFVNKADFP-KVRAKEQTFMFPENQPVSSLVTTITGSSL---RGEPMSYYIASGN 2607
TV + ++ D P + +A E T N S V + + ++Y + +
Sbjct: 2569 CTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPED 2628
Query: 2608 L-GNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNA 2666
L + +I+ +TG V + L + Q +I+A+DGG P ++S + + V+ +
Sbjct: 2629 LVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSL 2688
Query: 2667 PIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYEIVNG-----NMENSFSINHA 2721
P F E + E+L + + P + Y +V G N + FS++
Sbjct: 2689 PKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDP---VIYSLVRGTTPESNKDGVFSLDPD 2745
Query: 2722 TGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRF-SQIFSAH 2780
TG I+ +P+D E Y + + + + + V V I + D NDN P F + + A
Sbjct: 2746 TGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAV 2805
Query: 2781 VPENSPLGYTVTRVTTSDEDIGINAISRYSIM-----DASLPFTINPSTGDIVISRPLNR 2835
+ EN P+G +V +VT D+D G + Y + + F I+ +G I + L+
Sbjct: 2806 LTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDC 2865
Query: 2836 EDTDRYRIRVSAHDSGWTVSTD----VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKV 2891
E Y V A+D G T+ V + +TD NDNAPRF+ Y E +E G V
Sbjct: 2866 ETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELV 2925
Query: 2892 TQVFATDPD-EGSNGQVFYFIKSQSEY--FRINATTGE--IFNKQILKYQNVTGFSNVNI 2946
+ D D N QV +I F I+ E I +++ L ++
Sbjct: 2926 ATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTA------- 2978
Query: 2947 NRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVT 3006
++ VT+SD GK + TV I ++D NDN+PQ + Y V ++V G +++V+
Sbjct: 2979 -KYLLRVTASD-GK--FQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVS 3034
Query: 3007 AIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGN 3066
A D D N+++ Y + +FKLD TG ++ ++L + F + A D G
Sbjct: 3035 ATD-LDTDTNAQITYSLHGPG-AHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGG 3092
Query: 3067 PPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKY 3126
+ T+H+ +N P F SH + + ++ ++ + V V ARD D N + Y
Sbjct: 3093 RSCQADITLHVEDVNDN--APRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVY 3150
Query: 3127 SISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW-VARTGYCSVTVNVI 3185
S+ + EG F+I+++TG++ L K L E+T+ A D G + + +VTV+V+
Sbjct: 3151 SLPD-SAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVV 3209
Query: 3186 DVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDP 3245
+ D PVFL+ ++ V E+AP GT V+ L AT G V ++ F +D
Sbjct: 3210 GLEDYLPVFLNTEHSVQVPEDAPPGTEVLQL-ATLTRPGAEKTGYRVVSGNEQGRFRLDA 3268
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
TG++ LDFET Y L+++ TV + + NE+ P+F Y
Sbjct: 3269 RTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYST 3328
Query: 3306 EISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK 3365
+ E A G ++ V A+D D + ++ Y + G ++ F I+ K G++ V+ LDRE+
Sbjct: 3329 RVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQ 3388
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVTF 3425
SLK+ A + G + ++ + V ++ N P F LN YS + E PIG+ V
Sbjct: 3389 ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLN-YSTTVQENSPIGSKVLQ 3447
Query: 3426 VSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDS 3485
+ D DS + +S+ I GN AF + P G + L R Y L + A DS
Sbjct: 3448 LILSDPDSPENGPPYSFRITKGNNGSAFRVTPD-GWLVTAEGLSRRAQEWYQLQIQASDS 3506
Query: 3486 GTPSATGSASLLVTLEDINDNGP-------MLTVSEGEVMENKRPGTLVMTLQSTDPDLP 3538
G P + S+ V + + + P +TV E E G +V + +TD D
Sbjct: 3507 GIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQ-----GGMVGKIHATDRD-- 3559
Query: 3539 PNQGPFTYYLLSTGPATSYFSLSTA-GVLSTTREIDREQIADFYLSVVTKDSGVPQMSST 3597
Q TY L +FS+ G + + + R Y VT G ++T
Sbjct: 3560 -PQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQGLPR----GHYSFNVTVSDGT--FTTT 3612
Query: 3598 GTVHITV 3604
VH+ V
Sbjct: 3613 AGVHVYV 3619
Score = 933 bits (2411), Expect = 0.0
Identities = 860/3015 (28%), Positives = 1345/3015 (44%), Gaps = 227/3015 (7%)
Query: 47 QVFQVLEEQPPGT-LVGTIQTRP--GFTYRL------SESHALFAINSSTGALYTTSTID 97
Q VLE P T L T P GF +L F I TG L + +D
Sbjct: 720 QSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLD 779
Query: 98 RESLPSDVINLVVLSSAPTYPTEVRVL---VRDLNDNAPVFPDPSIVVTFKEDSSSGRQV 154
E+ ++N+ V + ++L V+D NDNAP FP +T ED+ G +
Sbjct: 780 YEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTI 839
Query: 155 ILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNP-SGEGAFLHLVSKGGLDREVT 213
T D+D NG Y ++ E +L+P +GE LV G LDRE
Sbjct: 840 AELTTKDADSEDNG--RVRYTLLSPTE------KFSLHPLTGE-----LVVTGHLDRESE 886
Query: 214 PQYQLLVEVEDKGEPKRR--GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQ 271
P+Y L VE D+ + + +T++D+NDN P + H + VPED G+ +
Sbjct: 887 PRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTF 946
Query: 272 VAAADADEGTNADIRYRLQD--EGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRG 329
+ A+D D G ++RY L D GT F++D TG + + LDFE R Y+L++ A D G
Sbjct: 947 LDASDPDLGPAGEVRYVLMDGAHGT-FRVDLMTGALILERELDFERRAGYNLSLWASDGG 1005
Query: 330 VPSLTGRAEALIQ--LLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADS 387
P L R ++ +LDVN+N + +F + V EN+ GT V ++ D DS
Sbjct: 1006 RP-LARRTLCHVEVIVLDVNEN---LHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDS 1061
Query: 388 PAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAP 447
+G + + G F + + +I+ + LDRE Y LTV D P
Sbjct: 1062 -GLDGELQYFLRAGTGLAAFSINQ----DTGMIQTLAPLDREFASYYWLTVLAVDRGSVP 1116
Query: 448 PGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLN 507
SSV + I V D ND+PP SQ V+ ++ E+AP G+ V + A D DS
Sbjct: 1117 -------LSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSK 1169
Query: 508 ANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQ 567
L ++I SGN +G+F I +GL++T LDRE + +L ++ D G S ++
Sbjct: 1170 GKLTFNITSGNYMGFFMIHPVTGLLSTAQQ--LDRENKDEHILEVTVLDNGEPSLKSTSR 1227
Query: 568 LVVTLLDVNDEKPVFSQPEGYDVSVVEN-APTGT-ELLMLRATDGDLGDNGTVRFSLQEA 625
+VV +LDVND P+FS + ++V + E +P + L A+D D G NG V +S++
Sbjct: 1228 VVVGILDVNDNPPIFSH-KLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIE-- 1284
Query: 626 ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDN 685
++D +F +D V+G +S+ S+ E + L + ATD G PP S+ R+++ +
Sbjct: 1285 DSDEEAFSIDLVTGVVSSSSTFTAGE--YNILTIKATDSGQPPLSASVRLHIEWIPWPRP 1342
Query: 686 SPV---FYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSR-FQVNAQ 741
S + F Y + E +P + +S G G ++IS GD+ F +
Sbjct: 1343 SSIPLAFDETYYSFTVMETDPVNHMVGVISVE----GRPGLFWFNISGGDKDMDFDIEKT 1398
Query: 742 SGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+G I LD ++ Y L + TDG + I I + + P F + Y
Sbjct: 1399 TGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIA--NINHHRPQFLETRYEVR 1456
Query: 802 VFENVALGYHVGSVSASTMDLNSNISYLITTGDQKG---MFAINQVTGQLTTANVID-RE 857
V ++ G + V A D ++ Y I G +F ++ +G L T +D
Sbjct: 1457 VPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGS 1516
Query: 858 EQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQ 914
S + L V+ + V I V+D N + P F Q +V + G + Q
Sbjct: 1517 GPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQ 1576
Query: 915 AKAVDPDEGVNGMVLYS-LKQNPKNLFAINEKNGTISLLGPLD-VHAGSYQIEILASDMG 972
+A+D D GVN V YS LK N + F IN G I+L LD + + + + A D G
Sbjct: 1577 VRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQG 1636
Query: 973 VPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIA 1032
PQ + ++V+ + ++P+F + Y V + ES PV S V A + E+
Sbjct: 1637 SPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAM-----SPSEVT 1691
Query: 1033 YTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILE 1091
Y + EGN F + G + + +LD E Y L + S+ A V V +I
Sbjct: 1692 YELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDII-- 1749
Query: 1092 DVNDNRPLFNSTNYTFYFEE---------EQRAGSFVGKVSAVDKDFGPNGEVRYSFEMV 1142
D NDN P+F + + E ++ FV + A D D N + Y +++
Sbjct: 1750 DENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFV--IHASDSDKEANSLLVY--KIL 1805
Query: 1143 QPD----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP---QPLKDQAT 1195
+P+ F++ G +T + D ES+ F F V DQG P P Q
Sbjct: 1806 EPEALKFFKIDPSMGTLTIVSEMDYESM------PSFQFCVYVHDQGSPVLFAPRPAQVI 1859
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEE 1255
+HV +D+ND+ P+F + Y+ I ++L V ASD D ++YSI GN +
Sbjct: 1860 IHV--RDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSE----VNYSIKTGNAD 1913
Query: 1256 RQFAIDSTSGQVTLIGKLDYEATPAY-----SLVIQAVDSGTIPLNSTCTLNIDILDEND 1310
I +G ++++ PA+ L I+A D T + I + D
Sbjct: 1914 EAVTIHPVTGSISVL-------NPAFLGLSRKLTIRASDG---LYQDTALVKISLTQVLD 1963
Query: 1311 NTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG 1370
+ F + + V EN++ + + + A + D Y+ + GT+ F + + G
Sbjct: 1964 KSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLS-YFLLNGTD---MFHMVQSAG 2019
Query: 1371 SI-FLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSI 1429
+ D E Q ++L + +D P R + V + + D NDNPP F + I
Sbjct: 2020 VLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTII 2079
Query: 1430 VENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFA 1489
+ G + V+A D D NG ++Y + +F ID G I D +
Sbjct: 2080 QDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDY---TYFRIDPYLGDISLKKPFDYQAL 2136
Query: 1490 NLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTT 1549
N + L V A D P +LVT N + P+F S P + ++ T
Sbjct: 2137 NKYHLKVIARDGGTP-----SLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENI--TLYTP 2189
Query: 1550 IMAADPDEGANGEIEYEIINGD-TDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLG 1607
I+ + Y I+ + F D +G L V L S+ + V ATD
Sbjct: 2190 ILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTA 2249
Query: 1608 -PERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA-SPRGSEAPVEY 1665
++T E+ + + P F+Q Y T + EG P T VI + A+ G V Y
Sbjct: 2250 LGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSY 2309
Query: 1666 YIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAE 1725
IV + V + F I TG + T LD E + V V A++K P T
Sbjct: 2310 QIVE---DGSDVSKFFQINGSTGEMSTVQELDYEAQQHFH-VKVRAMDKGDP-PLTGETL 2364
Query: 1726 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADD 1785
V + + DINDNPP F + V E G ++++ A+D D + + Y I+SG D
Sbjct: 2365 VVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQD 2424
Query: 1786 -SFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRP 1844
F I+ SG + + S Y+L V A DG+ + + + I ++ N ++P+F +
Sbjct: 2425 RHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQH 2484
Query: 1845 VYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRL- 1903
+Y ++ E+ + G+ V +LA D DSG G I Y + F +NP + L +L
Sbjct: 2485 LYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQKLD 2544
Query: 1904 LDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ ++ + V A DGGG+ V + D NDNPP F + Y+ S+ N+ S V
Sbjct: 2545 RENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPV 2604
Query: 1964 LVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDR----ESQSFYNLVVQ 2019
+ DAD+G N+ +TYS+ + + L + ++ N V V+K D E+Q+ +
Sbjct: 2605 IQVLAYDADEGQNADVTYSV-NPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKA 2663
Query: 2020 VHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-----IPENTPIDTVVFKAQA 2074
P + S V + ++ + P F P T+ +PE + I +V A
Sbjct: 2664 QDGGP----PHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIG-IVKAVAA 2718
Query: 2075 TDPDSGPNSYIEYTLL---NPLGNK---FSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
DP + Y+L+ P NK FS+ G +++ +D E Y + V+A
Sbjct: 2719 QDP-------VIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHC 2771
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
+ S V + V D+NDN P+F YK + EN GT +IQV A D D G +GQ
Sbjct: 2772 LQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQ 2831
Query: 2189 VRYGI---VNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPR-TDTST 2244
V Y + N ++ F IDS +G IT + LD E TYH V A D G T + + +
Sbjct: 2832 VSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQAL 2891
Query: 2245 VSIVLLDINDFVPVFELSPYSVNVPENL--GTLPRTILQVVARDDDRGSNSKLSYVLFGG 2302
V + + D ND P F Y +V EN G L T+ + A D N +++ + G
Sbjct: 2892 VQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDA--DISEQNRQVTCYITEG 2949
Query: 2303 NEDNAFTLSASGE---LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVND 2359
+ F +S G+ + ++LDRE +++L +TA+D A + T+ + V DVND
Sbjct: 2950 DPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQA---SVTVEIFVLDVND 3006
Query: 2360 NVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII---GGNSQFTINPSTGQ 2416
N P + Y + ED G +L V+A+D D NA I G +F ++P TG+
Sbjct: 3007 NSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGE 3066
Query: 2417 IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIP 2476
+ T LDRE KD + LV +D G S + + V DVNDN PRF +
Sbjct: 3067 LTTLTALDRERKDVFNLVAKATDGGG---RSCQADITLHVEDVNDNAPRFFPSHCAVAVF 3123
Query: 2477 SPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTF 2536
T + V V D D G N+++ YSL F ID G I PL +
Sbjct: 3124 DNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPL 3183
Query: 2537 SVHVKD---GGSFPKTDSTTVTVRFVNKADF-PKVRAKEQTFMFPENQPVSSLVTTITGS 2592
+ V+ G P + TVTV V D+ P E + PE+ P + V +
Sbjct: 3184 ELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATL 3243
Query: 2593 SLRG-EPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSS 2651
+ G E Y + SGN F++D TG + ++ LDFE KY + IE S
Sbjct: 3244 TRPGAEKTGYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSD 3303
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMDKDSGPNGQLDYEIVNG 2710
+ + + DVN++ P F +DP+ + +LEN L ILTVSA D+D N + Y ++ G
Sbjct: 3304 VTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGG 3363
Query: 2711 NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNA 2770
N F+I+ GE++ + LDRE+ S Y L ++++D G P + I + D NDN
Sbjct: 3364 NQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNP 3423
Query: 2771 PRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINA---ISRYSIMDASLPFTINPSTGD 2826
PRF Q+ +S V ENSP+G V ++ SD D N R + + F + P G
Sbjct: 3424 PRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPD-GW 3482
Query: 2827 IVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRFSRTSYYLDCPE 2883
+V + L+R + Y++++ A DSG + T V + VT+ + AP ++ E
Sbjct: 3483 LVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGE 3542
Query: 2884 LTEIGSKVTQVFATDPDEGSNGQVFYFIKSQ---SEYFRINATTGEIFNKQILKYQNVTG 2940
G V ++ ATD D + Y + + +F + A G+I Q L + +
Sbjct: 3543 DEFQGGMVGKIHATDRD--PQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQGLPRGHYS- 3599
Query: 2941 FSNVNINRHSFIVTS 2955
NV ++ +F T+
Sbjct: 3600 -FNVTVSDGTFTTTA 3613
Score = 592 bits (1526), Expect = e-168
Identities = 592/2207 (26%), Positives = 985/2207 (44%), Gaps = 257/2207 (11%)
Query: 1563 IEYEIINGD------TDTFIVDRYSGDLRVASALVPSQLI-------YNLIVSATDLGPE 1609
+ Y II+GD T+ ++V + LR+ + + L+ Y LI+ AT+ E
Sbjct: 69 VRYRIISGDVANVFKTEEYVVGNFCF-LRIRTKSSNTALLNREVRDSYTLIIQATEKTLE 127
Query: 1610 RRKSTTELTIILQGLD-GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIV 1668
T + IL D P+F+ P Y + E P+ + + + A + YY
Sbjct: 128 LEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAF 187
Query: 1669 SVRCEEKTVGRLFTIGRHTGIIQTAAILD-----REQGACLYLVDVYAIEKSTAF----- 1718
+ R E +F I +G++ A L+ + + L + + I + F
Sbjct: 188 NTRSE------MFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAA 241
Query: 1719 ------PRTQR----AEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDAD 1768
P ++ A V +T D ND T + V+ N G+++ + + D
Sbjct: 242 LVVHVEPALRKPPAIASVVVTPPDSNDG-----TTYATVLVDAN-SSGAEVESVEVVGGD 295
Query: 1769 EGAN--ALVTYTIISGADDSFRIDPESGDLIATRRLD-RERRSKYSLLVRADDG----LQ 1821
G + A+ +Y + F L++ + ++ E ++L ++A G
Sbjct: 296 PGKHFKAIKSY----ARSNEF-------SLVSVKDINWMEYLHGFNLSLQARSGSGPYFY 344
Query: 1822 SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVN 1881
S ++ S ++ + KF + VY + E + PGS V + T + Y++
Sbjct: 345 SQIRGFHLPPSKLS--SLKFEKAVYRVQLSEFSPPGSRVVMVRVTP----AFPNLQYVLK 398
Query: 1882 EDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNP 1941
E+ F LN TG+ T+L+D+ + +Y L +R GQ +T+ V +I+D N++
Sbjct: 399 PSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSP--GQASTV-VVIDIVDCNNHA 455
Query: 1942 PIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKN-GVL 2000
P+F+ +SY +L EN+P G++VL TD D G N +TYSIA +L F++D G++
Sbjct: 456 PLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKAL-PFSIDPYLGII 514
Query: 2001 KVLKALDRE-SQSFYNLVVQVHDLPQIPASRFTSTAQVSII--LLDVNDNPPTFLSPKLT 2057
K +D E + Y V+ D S F +VSI L ++NDN P F T
Sbjct: 515 STSKPMDYELMKRIYTFRVRASDW----GSPFRREKEVSIFLQLRNLNDNQPMFEEVNCT 570
Query: 2058 -YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTG---ELD 2113
I ++ P+ + A D D N E N L F + G + L L
Sbjct: 571 GSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNEL-EYFDLNHFSGVISLKRPFINLT 629
Query: 2114 REEVSNYTLTVVATDKGQPSLSSSTEVVVMVLD--------------------------- 2146
+ ++Y+L + A+D G+ S +T + +V D
Sbjct: 630 AGQPTSYSLKITASD-GKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIG 688
Query: 2147 ------------------INDNNPIFAQAL-YKVEINENTLTGTDIIQVFAADGDEGTNG 2187
IN P F +++ E+ T + ++ A D D G NG
Sbjct: 689 LQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNG 748
Query: 2188 QVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
++ Y I +GN F I+ TG +TVA PLD E T Y L V D G+ ++ +++
Sbjct: 749 KLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTV 808
Query: 2248 VLLDINDFVPVFELSPYSVNVPEN--LGTLPRTILQVVARDDDRGSNSKLSYVLFGGNED 2305
+ D ND P F Y + + E+ +GT TI ++ +D D N ++ Y L E
Sbjct: 809 NVKDWNDNAPRFPPGGYQLTISEDTEVGT---TIAELTTKDADSEDNGRVRYTLLSPTE- 864
Query: 2306 NAFTL-SASGELGVTQSLDRETKERFVLMITATDSGSPA--LTGTGTINVIVDDVNDNVP 2362
F+L +GEL VT LDRE++ R++L + A D S L + + ++DVNDN P
Sbjct: 865 -KFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSP 923
Query: 2363 TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII---GGNSQFTINPSTGQIIT 2419
++ +PED P GT + ++ASD D +R + G + F ++ TG +I
Sbjct: 924 QCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALIL 983
Query: 2420 SALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN--PPRFQHHPYVTHIPS 2477
LD E + Y L + SD G P + V V V DVN+N PP F + +
Sbjct: 984 ERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQE 1043
Query: 2478 PTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLRGAIMAAGPLNG--ASEV 2534
+ G+ V V D D G + EL Y L +G F I+ G I PL+ AS
Sbjct: 1044 NSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYY 1103
Query: 2535 TFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFP---ENQPVSSLVTTITG 2591
+V D GS P + T V + + D P Q +P E+ PV + V +
Sbjct: 1104 WLTVLAVDRGSVPLSSVTEVYIEVTDANDNPP--QMSQAVFYPSIQEDAPVGTSVLQLDA 1161
Query: 2592 ----SSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP 2647
SS +G+ +++ I SGN F I +TG +S +Q LD E ++++ + D G P
Sbjct: 1162 WDPDSSSKGK-LTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEP 1220
Query: 2648 PFSSYEKLDITVLDVNDNAPIFKEDPF---ISEILENLSPRKILTVSAMDKDSGPNGQLD 2704
S ++ + +LDVNDN PIF F + E L +SP + + A D D G NG++
Sbjct: 1221 SLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVT 1280
Query: 2705 YEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINIL 2764
Y I + + E +FSI+ TG + S + + +LTIK++D G P S SV++ I +
Sbjct: 1281 YSIEDSD-EEAFSIDLVTGVVSSSSTFTAGE--YNILTIKATDSGQPPLSASVRLHIEWI 1337
Query: 2765 DENDNAPRFSQI--------FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM--DA 2814
PR S I +S V E P+ + V ++ G + ++I D
Sbjct: 1338 P----WPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVE----GRPGLFWFNISGGDK 1389
Query: 2815 SLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIF-VTDINDNAPRFS 2873
+ F I +TG IVI+RPL+ Y + V D T++T V IF + +IN + P+F
Sbjct: 1390 DMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQFL 1449
Query: 2874 RTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE-----YFRINATTGEIF 2928
T Y + P+ T G ++ +V A D D+G + + Y I + F+++ ++G +
Sbjct: 1450 ETRYEVRVPQDTVPGVELLRVQAIDQDKGKS--LIYTIHGSQDPGSASLFQLDPSSGVLV 1507
Query: 2929 NKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKY 2988
+ K +G S +H+ V D+ P + VTI++ D N + P+F + Y
Sbjct: 1508 T--VGKLDLGSGPS-----QHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHY 1560
Query: 2989 FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLI 3048
V + GT+L++V A+ D D G+N+EV Y + N G F ++ G I++A L
Sbjct: 1561 EASVPDTIAPGTELLQVRAM-DADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLD 1619
Query: 3049 SDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIV 3108
+ +TV A+D+G+P ATV I V + P FS+S IPES +GS +
Sbjct: 1620 QANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPI 1679
Query: 3109 RTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTI--SA 3166
VSA + Y + GN++G+F++NS +G+++ K LD+E +++ I S
Sbjct: 1680 LLVSAMSPSE-----VTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSN 1734
Query: 3167 IDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLN-------AT 3219
+ G + V V++ID NDN+P+FL + + E AP + ++ N A+
Sbjct: 1735 MAGAFTD----VMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHAS 1790
Query: 3220 DADSGTNAVIAYTVQSSDS-DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDE 3276
D+D N+++ Y + ++ F IDP+ G +T +D+E+ S+ V + P
Sbjct: 1791 DSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVL 1850
Query: 3277 ERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYL 3336
A V I ++ N+ PRF ++Y I G + V ASD D EV+Y
Sbjct: 1851 FAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDE----DSEVNYS 1906
Query: 3337 IFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVL 3396
I + + I+ TG I V +++++ + G D V +++
Sbjct: 1907 IKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIR-------ASDGLYQDTALVKISLT 1959
Query: 3397 DANDPPI-FTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSI 3455
D + F ++Y + E + + + A + + SYF+ +G + F +
Sbjct: 1960 QVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDT---LSYFLLNGTD--MFHM 2014
Query: 3456 NPQTGQI-TVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPML---- 3510
G + T DRE + L+V D+ TP + V++ED+NDN P
Sbjct: 2015 VQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLP 2074
Query: 3511 --TVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLS 3567
T+ + + PG ++ + +TD DL N G TY +YF + G +S
Sbjct: 2075 YYTI----IQDGTEPGDVLFQVSATDEDLGTN-GAVTYEFAED---YTYFRIDPYLGDIS 2126
Query: 3568 TTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQS 3614
+ D + + ++L V+ +D G P + S V +TV ++++ QS
Sbjct: 2127 LKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQS 2173
Score = 572 bits (1473), Expect = e-162
Identities = 578/2129 (27%), Positives = 919/2129 (43%), Gaps = 176/2129 (8%)
Query: 1629 FTQPKYITILKEGEPIGTNVISIEAASPRGSEAP--VEYYIVS------VRCEEKTVGRL 1680
FT Y + E T V S E +E V Y I+S + EE VG
Sbjct: 33 FTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVANVFKTEEYVVGNF 92
Query: 1681 FTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVF 1740
+ T TA +L+RE L+ + A EK+ R V I D ND P+F
Sbjct: 93 CFLRIRTKSSNTA-LLNREVRDSYTLI-IQATEKTLELEALTRVVVHIL--DQNDLKPLF 148
Query: 1741 PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATR 1800
+T+ E++ S I ++TA DAD G NA Y + + F I P SG +
Sbjct: 149 SPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYA-FNTRSEMFAIHPTSGVVTVAG 207
Query: 1801 RLDRERRSKYSLLVRADDGLQ--SSDMRINITVSDVNDHTPKFSRPVYSFDI---PEDTI 1855
+L+ R K+ L V A D ++ S + V P +P + P D+
Sbjct: 208 KLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPPDSN 267
Query: 1856 PGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPI--TGVFNLTRLLDYEVQQY-- 1911
G+ A +L + SG E +V D + + F+L + D +Y
Sbjct: 268 DGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLH 327
Query: 1912 -YILTVRAEDGGGQFTTIRVY-FNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVT 1969
+ L+++A G G + ++ F++ + F Y L E P GS V++ VT
Sbjct: 328 GFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVT 387
Query: 1970 DADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPAS 2029
A + L S +++G + G++ K +D ++ Y L I S
Sbjct: 388 PAFPNLQYVLK---PSSENVGFKLNARTGLITTTKLMDFHDRAHYQL--------HIRTS 436
Query: 2030 RFTSTAQVSIILLDVNDNPPTF-LSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYT 2088
++ V I ++D N++ P F S + EN P T V ATD D G N Y+ Y+
Sbjct: 437 PGQASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYS 496
Query: 2089 LLNPLGNKFSIGTIDGEVRLTGELDREEVSN-YTLTVVATDKGQP-SLSSSTEVVVMVLD 2146
+ P FSI G + + +D E + YT V A+D G P + + + +
Sbjct: 497 IAGPKALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRN 556
Query: 2147 INDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDS 2206
+NDN P+F + I ++ G I+ + A D DE N ++Y IV+GN + F ++
Sbjct: 557 LNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQN--LKYEIVSGNELEYFDLNH 614
Query: 2207 VTGAITVAKP---LDREKTPTYHLTVQATD--RGSTPRT--------------------- 2240
+G I++ +P L + +Y L + A+D ++P T
Sbjct: 615 FSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFEVPVTCDKTG 674
Query: 2241 ---------------------DTSTVSIVLLDINDFVPVFE-LSPYSVNVPENLGTLPRT 2278
D S+ IN + P FE P S++V E++ +
Sbjct: 675 VLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESV-PINTP 733
Query: 2279 ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITAT 2337
+ ++ A D D G N KL YV+ GNE+ F + +G L V LD E ++L +T
Sbjct: 734 LARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVY 793
Query: 2338 DSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA 2397
D G+P + + V V D NDN P F Y TI ED GT + + DAD+ N
Sbjct: 794 DLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNG 853
Query: 2398 VIR--IIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSP-EPLSSSTSVLV 2454
+R ++ +F+++P TG+++ + LDRE++ Y L V D S L S T +++
Sbjct: 854 RVRYTLLSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLII 913
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFH 2514
T+ DVNDN P+ +P PG+ + + +D D+GP E+ Y L F
Sbjct: 914 TLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFR 973
Query: 2515 IDPLRGAIMAAGPLNGASEVTF--SVHVKDGGSFPKTDSTTVTVRFV-----NKADFPKV 2567
+D + GA++ L+ + S+ DGG P T V + P
Sbjct: 974 VDLMTGALILERELDFERRAGYNLSLWASDGGR-PLARRTLCHVEVIVLDVNENLHPPHF 1032
Query: 2568 RAKEQTFMFPENQPVSSLVTTITG----SSLRGEPMSYYIASGNLGNTFQIDQLTGQVSI 2623
+ EN P + V + S L GE + Y++ +G F I+Q TG +
Sbjct: 1033 ASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGE-LQYFLRAGTGLAAFSINQDTGMIQT 1091
Query: 2624 SQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLS 2683
PLD E Y + + A D G P SS ++ I V D NDN P + F I E+
Sbjct: 1092 LAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAP 1151
Query: 2684 -PRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLT 2742
+L + A D DS G+L + I +GN F I+ TG + + + LDRE ++L
Sbjct: 1152 VGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILE 1211
Query: 2743 IKSSDKGSPSQSTSVKVMINILDENDNAPRFS-QIFSAHVPEN-SPLG-YTVTRVTTSDE 2799
+ D G PS ++ +V++ ILD NDN P FS ++F+ +PE SP+ V R+ SD
Sbjct: 1212 VTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDL 1271
Query: 2800 DIGINAISRYSIMDA-SLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTD 2857
D G+N YSI D+ F+I+ TG V+S + + + A DSG +S
Sbjct: 1272 DEGLNGRVTYSIEDSDEEAFSIDLVTG--VVSSSSTFTAGEYNILTIKATDSGQPPLSAS 1329
Query: 2858 VTIFVTDINDNAP-----RFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIK 2912
V + + I P F T Y E + V + EG G ++ I
Sbjct: 1330 VRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISV----EGRPGLFWFNIS 1385
Query: 2913 --SQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVT 2970
+ F I TTG I I + + SN N+ + VT R I+
Sbjct: 1386 GGDKDMDFDIEKTTGSIV---IARPLDTRRRSNYNL---TVEVTDGSR----TIATQVHI 1435
Query: 2971 INIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLG 3030
I + N + PQFL+++Y V ++ G +L+RV AI D+D G + Y I G
Sbjct: 1436 FMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAI-DQDKG--KSLIYTIHGSQDPG 1492
Query: 3031 K---FKLDNDTGWISVASSL-ISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
F+LD +G + L + +TV +D+ P + V I V + N H
Sbjct: 1493 SASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHP 1552
Query: 3087 PEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGIL 3146
P F+Q H A++P++ + G+ + V A D D +N + YS+ GN EG F IN+ GI+
Sbjct: 1553 PRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGII 1612
Query: 3147 TLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLEN 3206
TLA+ LD H +T+ A D G +V ++V + ++P+F +YF + E+
Sbjct: 1613 TLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPES 1672
Query: 3207 APSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-LFVIDPNTGVITTQGFLDFETKQSYH 3265
P G+ ++ ++A + Y ++ + D +F ++ +G+I+TQ LD E SY
Sbjct: 1673 IPVGSPILLVSAMSPSE-----VTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQ 1727
Query: 3266 LTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE------ 3319
L ++ N+ + V + + N+ P F+ + +ISEAAP +++ +
Sbjct: 1728 LKIRGSNMAG--AFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPF 1785
Query: 3320 -VFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNF 3378
+ ASD D + + Y I K F+I+ G + + +D E V +
Sbjct: 1786 VIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQ 1845
Query: 3379 GSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSW 3437
GS V + V D ND PP F+ IY V I + G + V A D D
Sbjct: 1846 GSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDED----- 1900
Query: 3438 SRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLL 3497
S +Y I +GN + A +I+P TG I+V L+ L + + G T A +
Sbjct: 1901 SEVNYSIKTGNADEAVTIHPVTGSISV---LNPAFLGLSRKLTIRASDGLYQDT--ALVK 1955
Query: 3498 VTLEDINDNGPML--TVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPAT 3555
++L + D V V EN + ++ L + L +Y+LL+
Sbjct: 1956 ISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHL---NDTLSYFLLN--GTD 2010
Query: 3556 SYFSLSTAGVLSTTR-EIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQS 3614
+ + +AGVL T DREQ L+V +D+ PQ + G V +++ D NDNP +
Sbjct: 2011 MFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKF 2070
Query: 3615 RTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+ + + PG +L V D D+
Sbjct: 2071 KHLPYYTIIQDGTEPGDVLFQVSATDEDL 2099
Score = 65.9 bits (159), Expect = 1e-09
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 3859 CEIDIDECLPSPCHSGGTCHNLVG-GFSCSCPDGFTGRACERDINECLQSPCKNGAICQN 3917
C + D C + C +GG C G G+ C CP F+G+ CE+ C +PC G C
Sbjct: 3944 CCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCIL 4003
Query: 3918 FPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSG 3956
P +C C YTG CE C C Q G
Sbjct: 4004 SPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRG 4042
Score = 62.8 bits (151), Expect = 8e-09
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 21/106 (19%)
Query: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
D C C NGG C ++CKC P ++G CE
Sbjct: 3949 DYCSQNTCLNGGKCSWTHGAG---------------------YVCKCPPQFSGKHCEQGR 3987
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPC 3909
+ C +PC GGTC G SC+CP +TG CE + C + C
Sbjct: 3988 ENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHC 4033
Score = 57.4 bits (137), Expect = 4e-07
Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 3904 CLQSPCKNGAICQNFPGS-FNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYC 3962
C Q+ C NG C G+ + C C ++GK CE C PC GG+C C
Sbjct: 3951 CSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASC 4010
Query: 3963 HCPFGVFGKHCELNSYGFEE 3982
+CP G CE+ + G E
Sbjct: 4011 NCPHPYTGDRCEMEARGCSE 4030
Score = 56.2 bits (134), Expect = 8e-07
Identities = 57/240 (23%), Positives = 100/240 (41%), Gaps = 38/240 (15%)
Query: 3973 CELNSYGFEELSYMEFPSLDPNNNYIYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAE 4032
C + F SY+ + + N +I+ T++ A+LL+ N+T ++L++A
Sbjct: 3771 CNGTATRFSGQSYVRYRAPAARNWHIHFYLKTLQPQAILLFT--NETAS----VSLKLAS 3824
Query: 4033 ERLRFSYNLGSGTY-KLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSENQEPGYCTVSN 4091
+ Y+ G Y L++ + V+D +H+++ + L VDS
Sbjct: 3825 GVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTS--------- 3875
Query: 4092 VAVSDDWTLDVQPNR-VTVGGIRSLEPILQRRGHVESHDFVGCIMEFAVNGRPLE---PS 4147
V + ++P R + +GG+ IL S F GC+ VN L+ P
Sbjct: 3876 -LVVPENCRGLRPERHLLLGGL-----ILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPG 3929
Query: 4148 QALAA---QGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQ-----CHCKEGLTGKYCEK 4199
+ +A L QC C+++ C +GG C SW C C +GK+CE+
Sbjct: 3930 KTVAGLLETQALTQCCLHSDYCSQNTCLNGGKC----SWTHGAGYVCKCPPQFSGKHCEQ 3985
Score = 55.8 bits (133), Expect = 1e-06
Identities = 62/268 (23%), Positives = 105/268 (39%), Gaps = 51/268 (19%)
Query: 4298 YVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDA 4357
+V D WH+ L+ + + L VD + N ++ P G + LGG+ + +
Sbjct: 3846 HVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLGGLILLHSSSNV 3905
Query: 4358 QTAGFDGCIASMWYGGESLPF--SGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLC 4415
+ GF+GC+ ++ E+L GK ++A + +T A C C
Sbjct: 3906 -SQGFEGCLDAVVVNEEALDLLAPGK-TVAGLLETQ-------------ALTQC-----C 3945
Query: 4416 INQWYAYRCVPPGDCASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTCEM------VVACL 4469
++ Y C+ + C NGG C +G+ C CP +G+ CE CL
Sbjct: 3946 LHSDY---------CSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCL 3996
Query: 4470 G----VLCPQGKVCKAGSP-AGHVCVL-----SQG----PEEISLPLWAVPAIVGSCATV 4515
+L P+G C P G C + S+G EI W ++ V
Sbjct: 3997 EGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAV 4056
Query: 4516 LALLVLSLILCNQCRGKKAKNPKEEKKP 4543
+++ ++ L CR K+ P + P
Sbjct: 4057 AFIIISTVGLLFYCRRCKSHKPVAMEDP 4084
>gi|189571674 cadherin-like 23 isoform 1 precursor [Homo sapiens]
Length = 3354
Score = 1061 bits (2745), Expect = 0.0
Identities = 880/2873 (30%), Positives = 1352/2873 (47%), Gaps = 195/2873 (6%)
Query: 76 ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVF 135
E+ FA+ TG ++ +DRE+ + V +V + V D+NDNAP F
Sbjct: 73 EASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTF 132
Query: 136 PDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSG 195
+ V E++ G + + ATD D+G+ G S++ + F +D S
Sbjct: 133 HNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQ----PPSQFFAID-----SA 183
Query: 196 EGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYL-QVNVTVQDINDNPPVFGSSH 254
G + LD E T YQL V D+ + + L + + + D+ D P+F +
Sbjct: 184 RGIVTVIRE---LDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLP 240
Query: 255 YQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP--FQMDPETGLITVREPLD 312
Y + E + G++V + A D D+G I Y + T F +D +G++T+ LD
Sbjct: 241 YSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLD 300
Query: 313 FE---ARRQYSLTVQAM----DRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYA 365
E + LTV+ DR T I ++D+NDN P F ++
Sbjct: 301 RENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAP-----EFNSSEYSV 355
Query: 366 SVDENAQVGTVVAL-LTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLS--LIKV 422
++ E AQVG + L + V D D ++ L GN HF + + V + I+V
Sbjct: 356 AITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRV 415
Query: 423 ASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRV 482
A LD E + Y+ + ++ +V A + I + + ND+ P+FSQ +Y +
Sbjct: 416 AIPLDYETVDRYDFDLFANE--------SVPDHVGYAKVKITLINENDNRPIFSQPLYNI 467
Query: 483 NLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDR 542
+L E G+ V + ATD D+G + Y + F + + +GL+ LD
Sbjct: 468 SLYENVTVGTSVLTVLATDNDAGTFGEVSYFF--SDDPDRFSLDKDTGLIML--IARLDY 523
Query: 543 ELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
EL + L I ARD G + + ++ + +LDVND P F Q + Y ++ EN P+ T+L
Sbjct: 524 ELIQRFTLTIIARDGG--GEETTGRVRINVLDVNDNVPTF-QKDAYVGALRENEPSVTQL 580
Query: 603 LMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGR--LSTISSLDREE--QAFYSLL 658
+ LRATD D N + +S+ A F + G +S LD E+ L
Sbjct: 581 VRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLT 640
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDL 718
V+A D G+PP +S + + + D NDN P F YF + EN G+ + ++ATD D
Sbjct: 641 VMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDR 700
Query: 719 GTN-GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDG--GNLQSPN 775
G S ++F++NA+SG I+T LDRE K+ Y L + A DG G+ Q
Sbjct: 701 SREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTG 760
Query: 776 QAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQ 835
A V IT+LD DN P + Y + E V +V A DL N + + +
Sbjct: 761 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPP 820
Query: 836 KGMFAINQVTGQL-TTANVIDREEQSFYQL----KVVASGG-------TVTGDTMVNITV 883
+++N TG++ TT ++DRE ++ K+V S T V + +
Sbjct: 821 NKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNL 880
Query: 884 KDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQN-PKNLFAI 942
DLNDN P F V+E AG SI+Q A+D DEG+NG+V Y + P+ F I
Sbjct: 881 LDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLI 940
Query: 943 NEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSY 1001
N +G + LD YQ+ ++ASD G P SS+ LT++V DVND +P F Y
Sbjct: 941 NSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVY 1000
Query: 1002 EVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI-FPDGQLYIKSELDR 1060
V++SE P R + +D D G N E++Y I GN F + + D + LDR
Sbjct: 1001 NVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDR 1060
Query: 1061 ELQDRYVLMVVASDRAV----EPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAG 1116
E Y+L++ A D +ATV VTV+ DVNDNRP+F ++Y E+ G
Sbjct: 1061 ETTAAYMLILEAIDNGPVGKRHTGTATVFVTVL--DVNDNRPIFLQSSYEASVPEDIPEG 1118
Query: 1117 SFVGKVSAVDKDFGPNGEVRYSFEMVQ--PDFELHAISGEI-TNTHQFDRESLMRRRGTA 1173
+ ++ A D D G G V Y +F +H +G + DRE R +
Sbjct: 1119 HSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRE----RNSSH 1174
Query: 1174 VFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFY-QATISESAANLTQVLRV 1232
V D G P++ V VY++DIND AP F + Y + + E+A T V+ V
Sbjct: 1175 VLIVEAYNHDLG---PMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVV 1231
Query: 1233 SASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGT 1292
A+D D G+ GL++Y I+ G E +F ID ++G + + LDYE +Y + + A D
Sbjct: 1232 QATDRDSGDGGLVNYRILSG-AEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAP 1290
Query: 1293 IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADL-Y 1351
C++ I +L+E D F ++ +LEN+ +G + V A D+ + +
Sbjct: 1291 PFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRF 1350
Query: 1352 YSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
+ T T F I TG I + +D E Y L + A D G P ST+ V I V
Sbjct: 1351 NAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVA-DDGGPKVDSTVKVYITVL 1409
Query: 1412 DFNDNPPSFP-PGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRG--NH 1468
D NDN P F D SI E+ P+G V +V A DPDA NGQ+ +++ G
Sbjct: 1410 DENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEI 1469
Query: 1469 FTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPM 1528
T ++ G ++ +DRE + + L V A+D+ P + + L+ VTIL D+NDN P+
Sbjct: 1470 VTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQ-VTIL--DINDNPPV 1526
Query: 1529 FISQNA--LAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTD-TFIVDRYSGDL- 1584
S ++ + + G+ + + A D D G N + Y I G+ D F +DR SG++
Sbjct: 1527 IESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIA 1586
Query: 1585 -RVASALVPSQLIYNLIVSATDLGPERRKSTTE--LTIILQGLDGPVFTQPKYITILKEG 1641
R A Q Y+L+ + D G +TT +TI+ + + P+F QP Y +L EG
Sbjct: 1587 TRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEG 1646
Query: 1642 -EPIGTNVISIEAAS-PRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDRE 1699
+ + T++I+I+A G V Y IV+ + F I RH G+I A LD E
Sbjct: 1647 PDTLNTSLITIQALDLDEGPNGTVTYAIVA-----GNIVNTFRIDRHMGVITAAKELDYE 1701
Query: 1700 QGACLYLVDVYAIEKSTAFPR--TQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGS 1757
Y + V A ++ T V + + DINDN P FP D G
Sbjct: 1702 ISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPGP 1761
Query: 1758 KIMQLTAMDADEGANALVTYTIISGAD-DSFRIDPESGDLIATR--RLDRERRSKYSLLV 1814
++ A D D G N V Y+I+ G F I P G L + LDRE + Y+L +
Sbjct: 1762 RVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTI 1821
Query: 1815 RA-DDGLQ--SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSG 1871
A D G+ SS M + I V D+ND+ P + I E++ S VA +LA+D DSG
Sbjct: 1822 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSG 1881
Query: 1872 VNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVY 1931
N +T+ + + + FF+N TG+ + R LD E Y LT+ +D R
Sbjct: 1882 CNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRD 1941
Query: 1932 FNIL-----DVNDNPPIFSLNSYSTSLMENLPVGSTVLVFN----VTDADDGINSQLTYS 1982
+++L D NDN P+F+ ++Y +MEN P G+ + V N DAD I + +TY
Sbjct: 1942 YDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQ 2001
Query: 1983 IASGDSLGQFTVDKN-GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIIL 2041
+ S G F ++ + GV+ V + + ++F ++++ L + STA + I +
Sbjct: 2002 LLGAQS-GLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAE-DIGLLNSTAHLLITI 2059
Query: 2042 LDVNDNPPTFLSPKLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
LD NDN PTF LT ++ EN P V + ATD DSG N + Y + ++F I
Sbjct: 2060 LDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIH 2119
Query: 2101 TIDGEVRL-TGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 2159
+ G +R+ +DREE +Y LTVVATD+G LS + V +++ DIND+ P F +
Sbjct: 2120 LVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQ 2179
Query: 2160 KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVN-----------GNTNQEFRIDSVT 2208
V + E+ GT I + A D D N ++ Y IV N F ++ T
Sbjct: 2180 TVSVLESAEPGTVIANITAIDHD--LNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINT 2237
Query: 2209 GAITVAKPLDREKTPTYHLTVQATDRGS-TPRTDTST----VSIVLLDINDFVPVFE--- 2260
G++ V P++RE TY +T+ D S P S +++ +LD+ND P F+
Sbjct: 2238 GSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFG 2297
Query: 2261 LSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL--SASGELGV 2318
++ Y + E T T++ V A D D+G N ++Y L L S++G++
Sbjct: 2298 ITYYMERILEG-ATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIA 2356
Query: 2319 TQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAP 2378
+++D E + A+D+GSP + + + D+NDN P F +Y + ED P
Sbjct: 2357 NRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVP 2416
Query: 2379 TGTDVLLVNASDADASKNAVIR--IIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVV 2436
GT +L V A+DAD+ A+I + G S+F INP+TG I + LDRE KD+Y L +
Sbjct: 2417 VGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYILTAL 2476
Query: 2437 CSDAGSPEPLSS-----STSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVT 2491
D +P ++S S V++ V DVND P+F + T + G+ V + T
Sbjct: 2477 AKD--NPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMAT 2534
Query: 2492 DADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTDS 2551
D D GPN EL YSL G E FH+D G + PL + + +V DGG P +
Sbjct: 2535 DQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGT 2594
Query: 2552 TTVTVRFVNKADFPK--VRAKEQTFM-----FPENQPVSSLVTTITGSSLRGE-PMSYYI 2603
T + V ++ D VR T + P V + T L G S+
Sbjct: 2595 TMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLK 2654
Query: 2604 ASGNLG-NTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP-PFSSYEKLDITVLD 2661
+GN F ID ++G + +Q LD E Y + + A D G P P+ + + L + + D
Sbjct: 2655 TAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALED 2714
Query: 2662 VNDNAPIFKEDPFISEILENL-----SPRKIL---TVSAMDKDSGPNGQLDYEIVNGNME 2713
++DN P+F P S + L SPR L A+D D GPN + Y I GN E
Sbjct: 2715 IDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEE 2774
Query: 2714 NSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGS------PSQS-------TSVKVM 2760
+F + G + +R LDRE+ + + +K+S S PS + T +V
Sbjct: 2775 KNFHL-QPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVR 2833
Query: 2761 INILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM 2812
+ + D ND PRF++ ++A V ++ +G + +V D DIG N++ YSI+
Sbjct: 2834 VVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYSIL 2886
Score = 1024 bits (2648), Expect = 0.0
Identities = 894/2943 (30%), Positives = 1374/2943 (46%), Gaps = 227/2943 (7%)
Query: 364 YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
Y + E+ VG+ V L D D N + + G R F V+ P+ ++ +
Sbjct: 39 YLLISEDTPVGSSVTQLLAQDMD----NDPLVFGVSGEEASRFFAVE----PDTGVVWLR 90
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
LDRE + + SVSD+ G + I V D+ND+ P F Q Y V
Sbjct: 91 QPLDRETKSEFTVEFSVSDHQGV----------ITRKVNIQVGDVNDNAPTFHNQPYSVR 140
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ E P G+ + ++ATD D G ++ YS + +F I G+VT LD E
Sbjct: 141 IPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQ--FFAIDSARGIVTVIRE--LDYE 196
Query: 544 LASQIVLNISARDQG-VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
L ++A DQ P + A L + + DV D P+F Y ++ E++P GT +
Sbjct: 197 TTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLP-YSTNIYEHSPPGTTV 255
Query: 603 LMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAF---YSLLV 659
++ A D D G + +++ T+ F LD +SG L+ LDRE + + L V
Sbjct: 256 RIITAIDQDKGRPRGIGYTIVSGNTNS-IFALDYISGVLTLNGLLDRENPLYSHGFILTV 314
Query: 660 LATDLGSPPQSSMARI----NVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---VS 712
T+L S A + N+ ++DINDN+P F +Y I E G + V
Sbjct: 315 KGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVV 374
Query: 713 ATDPDLGTNGTVKYSISAGDRSRFQVNAQS----GVISTRMA--LDREEKTAYQLQIVAT 766
D +LG N + + + F ++ S I R+A LD E Y + A
Sbjct: 375 DKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFAN 434
Query: 767 DGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNS-- 824
+ A V IT+++ DN P+FSQ Y+ ++ENV +G V +V A+ D +
Sbjct: 435 ESVP-DHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFG 493
Query: 825 NISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA-SGGTVTGDTMVNITV 883
+SY + D F++++ TG + +D E + L ++A GG V I V
Sbjct: 494 EVSYFFS--DDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINV 551
Query: 884 KDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPK--NLFA 941
D+NDN P F + + EN + + + +A D D N + YS+ + F
Sbjct: 552 LDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFD 611
Query: 942 IN--EKNGTISLLGPLD---VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVF 996
I+ E G IS+ PLD + G + ++A D G P L+S+V +T+ V D NDN P F
Sbjct: 612 ISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTF 671
Query: 997 DQLSYEVTLSESEPVNSRFFKVQASDKDSG---ANGEIAYTIAEGNTGDAFGIFPDGQLY 1053
+ +Y V++ E+ + + A+D D I Y++ EG+T G++
Sbjct: 672 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSL-EGSTQFRINA-RSGEIT 729
Query: 1054 IKSELDRELQDRYVLMVVASDRAV----EPLSATVNVTVILEDVNDNRPLFNSTNYTFYF 1109
S LDRE + Y+L+V A D V + ATVN+T++ D+NDN P + Y
Sbjct: 730 TTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLL--DINDNHPTWKDAPYYINL 787
Query: 1110 EEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTH-QFDRESLMR 1168
E S V V AVD D G NG + YS + + L++ +G+I TH DRE+
Sbjct: 788 VEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDP 847
Query: 1169 RRGTAVFSFTVIATDQGIPQPLK--DQATVHVYMKDINDNAPKFLKDFYQATISESAANL 1226
+ V TD G P PLK ATV V + D+NDN P F + A + E
Sbjct: 848 HEAELMRKIVVSVTDCGRP-PLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAG 906
Query: 1227 TQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQ 1286
+ +V A D+DEG NGL+ Y + G F I+S+SG V +LD E Y L +
Sbjct: 907 VSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVV 966
Query: 1287 AVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGD 1346
A D+GT +ST TL I +LD ND TP+F + V V E++ V + TD+D G
Sbjct: 967 ASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGL 1026
Query: 1347 NADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPR--SSTM 1404
NA+L Y ITG N G FS+ + LD ET + Y L + A D G + + T
Sbjct: 1027 NAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTA 1086
Query: 1405 SVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMP 1464
+V + V D NDN P F S+ E+IP G S++ + A D D G++ Y I+
Sbjct: 1087 TVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHG-N 1145
Query: 1465 RGNHFTIDEVKGTIYTNAE-IDREFANLFELTVKA-NDQAVPIETRRYALKNVTILVTDL 1522
GN+F I G + +DRE + L V+A N P+ + V + V D+
Sbjct: 1146 HGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSS----VRVIVYVEDI 1201
Query: 1523 NDNVPMFISQ--NALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRY 1580
ND P+F Q + L +A IG+ + + A D D G G + Y I++G F +D
Sbjct: 1202 NDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDES 1261
Query: 1581 SGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTI-ILQGLDGPV-FTQPKYITI 1637
+G + + L ++ Y + VSATD P + + I +L LD V F+ Y
Sbjct: 1262 TGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAA 1321
Query: 1638 LKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILD 1697
+ E +GT ++ ++A S + + K LF I TG+I ++D
Sbjct: 1322 ILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKA---LFKIDAITGVITVQGLVD 1378
Query: 1698 REQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFP-TDMLDLTVEENIGDG 1756
RE+G Y + V A + T +V IT+ D NDN P F T +++ E+ G
Sbjct: 1379 REKGD-FYTLTVVADDGGPKVDST--VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVG 1435
Query: 1757 SKIMQLTAMDADEGANALVTYTI----ISGADDSFRIDPESGDLIATRRLDRERRSKYSL 1812
++ + A D D G+N V +++ I+GA + + G++ R LDRE Y L
Sbjct: 1436 QRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYIL 1495
Query: 1813 LVRADD---GLQSSDMRINITVSDVNDHTPKFSRPV-YSFDIPEDTIPGSLVAAILATDD 1868
V A D + D + +T+ D+ND+ P P Y+ + E+ G+ V + ATD
Sbjct: 1496 QVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDR 1555
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITG-VFNLTRLLDYEVQQYYILTVRAEDGGGQ--F 1925
D G+N ++Y + E ++D F ++ I+G + D E Q +Y L ED G
Sbjct: 1556 DIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLS 1615
Query: 1926 TTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLV-FNVTDADDGINSQLTYSIA 1984
T VY I+D NDN P+F Y L E +T L+ D D+G N +TY+I
Sbjct: 1616 ATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIV 1675
Query: 1985 SGDSLGQFTVDKN-GVLKVLKALDRE-SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILL 2042
+G+ + F +D++ GV+ K LD E S Y L+V D I + R TST V + +
Sbjct: 1676 AGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVN 1735
Query: 2043 DVNDNPPTFLSPK----LTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLL--NPLGNK 2096
D+NDN PTF P+ + E P V+ A D DSGPN +EY+++ +PLG +
Sbjct: 1736 DINDNVPTF--PRDYEGPFEVTEGQP-GPRVWTFLAHDRDSGPNGQVEYSIMDGDPLG-E 1791
Query: 2097 FSIGTIDG--EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIF 2154
F I ++G VR ELDRE ++ Y LT+ A D+G P LSS+ V + VLDINDN+P+
Sbjct: 1792 FVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVL 1851
Query: 2155 AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVA 2214
+ I+EN+ + + V A+D D G N ++ + I GN + F I++ TG +TV
Sbjct: 1852 LNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVN 1911
Query: 2215 KPLDREKTPTYHLTVQATDRGSTP---RTDTSTVSIVLLDINDFVPVFELSPYSVNVPEN 2271
+PLDRE+ P Y LT+ D P R D + I L D ND P+F S Y V EN
Sbjct: 1912 RPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMEN 1971
Query: 2272 --LGTLPRTILQ--VVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQS---LDR 2324
GT P T+L ++A D D+ + ++Y L G + F +++S + +S +DR
Sbjct: 1972 SPAGT-PLTVLNGPILALDADQDIYAVVTYQLLGA-QSGLFDINSSTGVVTVRSGVIIDR 2029
Query: 2325 ETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVL 2384
E +L + L T + + + D NDN PTF+ + E+ P G VL
Sbjct: 2030 EAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVL 2089
Query: 2385 LVNASDADASKNA--VIRI-IGGNSQFTINPSTGQI-ITSALLDRETKDNYTLVVVCSDA 2440
V A+D D+ N V RI G +F I+ TG I + +A +DRE +++Y L VV +D
Sbjct: 2090 QVTATDEDSGLNGELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDR 2149
Query: 2441 GSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSE 2500
G+ PLS + V + + D+ND+ P F + + PG+ + +T D D+ P E
Sbjct: 2150 GT-VPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLE 2208
Query: 2501 LHY----------SLSGRNSEKFHIDPLRGAIMAAGPLN----GASEVTFSVHVKDGGSF 2546
H L + F ++ G++M P+N EVT SV + +
Sbjct: 2209 YHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSV-IDNASDL 2267
Query: 2547 PKTD------STTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITG-------SS 2593
P+ TV V VN + P+ + T+ ++ TT+
Sbjct: 2268 PERSVSVPNAKLTVNVLDVND-NTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKG 2326
Query: 2594 LRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYE 2653
L G + G D G+V ++ +D+E++ + A D G PP ++
Sbjct: 2327 LNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEI 2386
Query: 2654 KLDITVLDVNDNAPIFKEDPFISEILENLSPRK-ILTVSAMDKDSGPNGQLDYEIVNGNM 2712
+ + ++D+NDN PIF + + + E++ ILTV+A D DSG ++Y + G+
Sbjct: 2387 PVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSL--GDG 2444
Query: 2713 ENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDK----GSPSQSTSVKVMINILDEND 2768
E+ F+IN TG+I + LDREK HY+LT + D S + SV+V+I +LD ND
Sbjct: 2445 ESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVND 2504
Query: 2769 NAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL-PFTINPSTGD 2826
P+FS+ FS V EN P G +V + +D+D G N YS+ + F ++ +G
Sbjct: 2505 CRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGL 2564
Query: 2827 IVISRPLNREDTDRYRIRVSAHDSG----WTVSTDVTIFVTDINDNAPRFSR--TSYYLD 2880
+ RPL + +++ + V A D G W +T + + V D+NDN P F R L
Sbjct: 2565 VTTQRPL--QSYEKFSLTVVATDGGEPPLWG-TTMLLVEVIDVNDNRPVFVRPPNGTILH 2621
Query: 2881 CPELTEIGSKVTQVFATDPDEGSNGQVFY-FIKSQS----EYFRINATTGEIFNKQILKY 2935
E + S V +V+ATD DEG NG V Y F+K+ E+F I+ +G I Q L
Sbjct: 2622 IREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDR 2681
Query: 2936 QNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV--DSNDNAPQFLKSKYFTP-- 2991
++ + S I+ +SD G+P + ET + + D +DN P F++ +P
Sbjct: 2682 ESQAVY--------SLILVASDLGQP-VPYETMQPLQVALEDIDDNEPLFVRPPKGSPQY 2732
Query: 2992 ----VTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSL 3047
V ++ GT + VT D D G N+ V YFI+ N F L D G + V L
Sbjct: 2733 QLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPD-GCLLVLRDL 2791
Query: 3048 ISDLNQ--NFFITVTAKDKGNPPLSSQAT-----------VHITVTEENYHTPEFSQSHM 3094
+ +F + ++ PP T V + + + N P F+++
Sbjct: 2792 DREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2851
Query: 3095 SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSI-----------SSGNEEGIFAINSST 3143
+A + +GS + V A D D N L+ YSI S + +F + S
Sbjct: 2852 TAGVATDAKVGSELIQVLALDADIGNNSLVFYSILAIHYFRALANDSEDVGQVFTMGSMD 2911
Query: 3144 GIL 3146
GIL
Sbjct: 2912 GIL 2914
Score = 1020 bits (2638), Expect = 0.0
Identities = 883/2908 (30%), Positives = 1371/2908 (47%), Gaps = 222/2908 (7%)
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+SE+ P GS V+ + A D D N L + + +F + +G+V LDRE
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEEASRFFAVEPDTGVVWLRQP--LDRE 96
Query: 544 LASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVF-SQPEGYDVSVVENAPTGTEL 602
S+ + S D H V ++ + + DVND P F +QP Y V + EN P GT +
Sbjct: 97 TKSEFTVEFSVSD---HQGVITRKVNIQVGDVNDNAPTFHNQP--YSVRIPENTPVGTPI 151
Query: 603 LMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLAT 662
++ ATD DLG G+V +S Q + F +D G ++ I LD E Y L V AT
Sbjct: 152 FIVNATDPDLGAGGSVLYSFQPPS---QFFAIDSARGIVTVIRELDYETTQAYQLTVNAT 208
Query: 663 DLGSP-PQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
D P S++A + + + D+ D P+F + Y +I E+ P G+ + ++A D D G
Sbjct: 209 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRP 268
Query: 722 GTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKT---AYQLQIVATDGGNLQSPNQA 777
+ Y+I +G+ S F ++ SGV++ LDRE + L + T+ + ++P+ A
Sbjct: 269 RGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDA 328
Query: 778 IVTIT----VLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNIS------ 827
VT T V+D DN P F+ YS + E +G+ + + +D + N+
Sbjct: 329 TVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFAL-PLFIQVVDKDENLGLNSMFE 387
Query: 828 -YLITTGDQKGMFAINQVTGQ----LTTANVIDREEQSFYQLKVVASGGTV--TGDTMVN 880
YL+ + + V G+ + A +D E Y + A+ G V
Sbjct: 388 VYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVK 447
Query: 881 ITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLF 940
IT+ + NDN P F Q + ++++ EN G S+ A D D G G V Y +P F
Sbjct: 448 ITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDR-F 506
Query: 941 AINEKNGTISLLGPLDVHA-GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL 999
++++ G I L+ LD + + I+A D G + + V + V DVNDN P F +
Sbjct: 507 SLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVL--DVNDNVPTFQKD 564
Query: 1000 SYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLY------ 1053
+Y L E+EP ++ +++A+D+DS N +I Y+I + AFG + D LY
Sbjct: 565 AYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSAS---AFGSYFDISLYEGYGVI 621
Query: 1054 -IKSELDRELQDRYV--LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFE 1110
+ LD E + L V+A D PL++TV VT+ + D NDN P F+ Y
Sbjct: 622 SVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVV 681
Query: 1111 EEQRAGSFVGKVSAVDKD----FGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESL 1166
E AG+ V ++A D D +G + YS E F ++A SGEIT T DRE+
Sbjct: 682 ENIMAGATVLFLNATDLDRSREYGQESII-YSLEG-STQFRINARSGEITTTSLLDRET- 738
Query: 1167 MRRRGTAVFSFTVIATDQGIPQPLKDQ-ATVHVYMKDINDNAPKFLKDFYQATISESAAN 1225
+ + V A D G+ K ATV++ + DINDN P + Y + E
Sbjct: 739 -----KSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPP 793
Query: 1226 LTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQV-TLIGKLD------YEAT 1278
+ V V A D D G NG + YSI N + ++++ST+G++ T LD +EA
Sbjct: 794 DSDVTTVVAVDPDLGENGTLVYSIQPPN--KFYSLNSTTGKIRTTHAMLDRENPDPHEAE 851
Query: 1279 PAYSLVIQAVDSGTIPLNST--CTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSS 1336
+V+ D G PL +T T+ +++LD NDN P+F +VLE + G +
Sbjct: 852 LMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQ 911
Query: 1337 VTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQG 1396
V A D D G N + Y + F I+ ++G + +LD E + Y+L + A D G
Sbjct: 912 VVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAG 971
Query: 1397 RPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLS 1456
P +SST ++ IHV D ND P+F P S+ E++P V+ + D D +N +LS
Sbjct: 972 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELS 1031
Query: 1457 YTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVT 1516
Y I G F++ + T +DRE + L ++A D P+ R V
Sbjct: 1032 YFITGGNVDGK-FSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNG-PVGKRHTGTATVF 1089
Query: 1517 ILVTDLNDNVPMFISQNALAADPSAVI-GSVLTTIMAADPDEGANGEIEYEIINGDT-DT 1574
+ V D+NDN P+F+ + A+ P + G + + A D DEG G + Y I++G+ +
Sbjct: 1090 VTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNN 1149
Query: 1575 FIVDRYSGDLRVASALVPSQL--IYNLIVSAT--DLGPERRKSTTELTIILQGL--DGPV 1628
F + +G L + + + LIV A DLGP R S+ + + ++ + + PV
Sbjct: 1150 FRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMR--SSVRVIVYVEDINDEAPV 1207
Query: 1629 FTQPKYITI-LKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHT 1687
FTQ +Y + L+E IGT+VI ++A + + Y + E K F I T
Sbjct: 1208 FTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGK-----FEIDEST 1262
Query: 1688 GIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDL 1747
G+I T LD E Y+++V A +++ F + V ITL + D F +
Sbjct: 1263 GLIITVNYLDYETKTS-YMMNVSATDQAPPFNQGF-CSVYITLLNELDEAVQFSNASYEA 1320
Query: 1748 TVEENIGDGSKIMQLTAMDADEGANALVTYTIISG--ADDSFRIDPESGDLIATRRLDRE 1805
+ EN+ G++I+++ A D + + A F+ID +G + +DRE
Sbjct: 1321 AILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDRE 1380
Query: 1806 RRSKYSLLVRADDGLQSSD--MRINITVSDVNDHTPKFSRPVYS-FDIPEDTIPGSLVAA 1862
+ Y+L V ADDG D +++ ITV D ND++P+F S IPED G VA
Sbjct: 1381 KGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVAT 1440
Query: 1863 ILATDDDSGVNGEITYIVNEDDEDGIFFL---NPITGVFNLTRLLDYEVQQYYILTVRAE 1919
+ A D D+G NG++ + + + G F + N G + R LD E +YIL V A
Sbjct: 1441 VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVAS 1500
Query: 1920 DGGGQFTTIR-----VYFNILDVNDNPPIF-SLNSYSTSLMENLPVGSTVLVFNVTDADD 1973
D G T R + ILD+NDNPP+ S Y+ S+ EN+ G+ V+ TD D
Sbjct: 1501 DRG---TPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDI 1557
Query: 1974 GINSQLTYSIASGDSLGQFTVDK-NGVLKVLKAL-DRESQSFYNLVVQVHDLPQIPASRF 2031
GINS L+Y I G+ F +D+ +G + A DRE QSFY+LV V D
Sbjct: 1558 GINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEG---TPTL 1614
Query: 2032 TSTAQVSIILLDVNDNPPTFLSPKLTYIPENTP--IDTVVFKAQATDPDSGPNSYIEYTL 2089
++T V + ++D NDN P F P + + P ++T + QA D D GPN + Y +
Sbjct: 1615 SATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAI 1674
Query: 2090 L-NPLGNKFSIGTIDGEVRLTGELDRE-EVSNYTLTVVATDKG---QPSLSSSTEVVVMV 2144
+ + N F I G + ELD E YTL V ATD+ L+S+T V+V V
Sbjct: 1675 VAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNV 1734
Query: 2145 LDINDNNPIFAQALY-KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFR 2203
DINDN P F + E+ E G + A D D G NGQV Y I++G+ EF
Sbjct: 1735 NDINDNVPTFPRDYEGPFEVTEGQ-PGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFV 1793
Query: 2204 IDSVTGAITVAKP--LDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL 2261
I V G + V K LDRE Y+LT+ A DRG P + T V I +LDIND PV
Sbjct: 1794 ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLN 1853
Query: 2262 SPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSAS-GELGVTQ 2320
P ++ + EN + + V+A D D G N++L++ + GN + AF ++A+ G + V +
Sbjct: 1854 LPMNITISEN-SPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNR 1912
Query: 2321 SLDRETKERFVLMITATDSGSP---ALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDA 2377
LDRE + L I+ D+ A + + + D NDN P F Y + E++
Sbjct: 1913 PLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENS 1972
Query: 2378 PTGTDVLLVN----ASDADASKNAVI--RIIGGNSQ-FTINPSTGQII--TSALLDRE-- 2426
P GT + ++N A DAD AV+ +++G S F IN STG + + ++DRE
Sbjct: 1973 PAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAF 2032
Query: 2427 TKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVF 2486
+ L+++ D G L+S+ +L+T+ D NDN P F H+ PG V
Sbjct: 2033 SPPILELLLLAEDIGL---LNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVL 2089
Query: 2487 AVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASE---VTFSVHVKDG 2543
VT TD D G N EL Y + ++F I + G I E +V D
Sbjct: 2090 QVTATDEDSGLNGELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDR 2149
Query: 2544 GSFPKTDSTTVTVRFVNKADF-PKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYY 2602
G+ P + + VT+ + D P+ QT E+ +++ IT P Y
Sbjct: 2150 GTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEY 2209
Query: 2603 IASG------------NLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP-PF 2649
G N + F ++ TG V + P++ E + Y V + D P
Sbjct: 2210 HIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPE 2269
Query: 2650 SSYE----KLDITVLDVNDNAPIFKE---DPFISEILENLSP-RKILTVSAMDKDSGPNG 2701
S KL + VLDVNDN P FK ++ ILE +P ++ V+A+D D G NG
Sbjct: 2270 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNG 2329
Query: 2702 QLDYEIVNGNMENSFSINHAT-GEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVM 2760
+ Y +++ + ++ G++ + R +D E+V T+++SD GSP ++ + V
Sbjct: 2330 LVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVY 2389
Query: 2761 INILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFT 2819
+ I+D NDN P F Q + V E+ P+G + VT +D D G A+ YS+ D F
Sbjct: 2390 LEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFA 2449
Query: 2820 INPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTV-------STDVTIFVTDINDNAPRF 2872
INP+TGDI + L+RE D Y + A D+ V S V I V D+ND P+F
Sbjct: 2450 INPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQF 2509
Query: 2873 SRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQS-EYFRINATTGEIFNKQ 2931
S+ + E G+ V + ATD DEG NG++ Y ++ E F ++ +G + ++
Sbjct: 2510 SKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQR 2569
Query: 2932 ILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFT- 2990
L+ + + S V ++D G+P L T + + ++D NDN P F++ T
Sbjct: 2570 PLQ----------SYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTI 2619
Query: 2991 -PVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFI---SNDNHLGKFKLDNDTGWISVASS 3046
+ + + + + + V A D KD GLN V Y + + F +D +G I A
Sbjct: 2620 LHIREEIPLRSNVYEVYATD-KDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQR 2678
Query: 3047 LISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTEENYHTPEF------SQSHMSATIP 3099
L + + + + A D G P P + + + + + + + P F S + T+P
Sbjct: 2679 LDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVP 2738
Query: 3100 ESHSIGSIVRTVS-ARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQ 3158
E G++V V+ A D D N ++ Y I++GNEE F + G L + + LD E
Sbjct: 2739 EHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPD-GCLLVLRDLDREREA 2797
Query: 3159 KHEMTISAIDG-GW------------VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLE 3205
+ A W VA V V + D+ND P F +Y V
Sbjct: 2798 IFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVAT 2857
Query: 3206 NAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+A G+ +I + A DAD G N+++ Y++
Sbjct: 2858 DAKVGSELIQVLALDADIGNNSLVFYSI 2885
Score = 1020 bits (2637), Expect = 0.0
Identities = 889/2903 (30%), Positives = 1338/2903 (46%), Gaps = 225/2903 (7%)
Query: 177 IRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQV 236
+ G EA RF + P +L + LDRE ++ + V D R +V
Sbjct: 69 VSGEEASRF---FAVEPDTGVVWL----RQPLDRETKSEFTVEFSVSDHQGVITR---KV 118
Query: 237 NVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPF 296
N+ V D+NDN P F + Y +PE+ VG+ + V A D D G + Y Q F
Sbjct: 119 NIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFF 178
Query: 297 QMDPETGLITVREPLDFEARRQYSLTVQAMDRG-VPSLTGRAEALIQLLDVNDNDPVVKF 355
+D G++TV LD+E + Y LTV A D+ L+ A I + DV D DP+ F
Sbjct: 179 AIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPI--F 236
Query: 356 RYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVP 415
P ++ ++ E++ GT V ++T D D G I I+ GN F +
Sbjct: 237 INLPYST---NIYEHSPPGTTVRIITAIDQDKGRPRG-IGYTIVSGNTNSIFALDYIS-- 290
Query: 416 NLSLIKVASALDRERIPSYN----LTVSVSD-NYGAPPGAAVQARSSVASLVIFVNDIND 470
++ + LDRE P Y+ LTV ++ N P A + + I V DIND
Sbjct: 291 --GVLTLNGLLDREN-PLYSHGFILTVKGTELNDDRTPSDA----TVTTTFNILVIDIND 343
Query: 471 HPPVFSQQVYRVNLSEEAPPG-SYVSGISATDGDSGLNANLRYSI-VSGNGLGWFHISEH 528
+ P F+ Y V ++E A G + I D D L N + + + GN S H
Sbjct: 344 NAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNN------SHH 397
Query: 529 SGLVTTGSSGGLDRELASQIVLNISARD---------QGVHPKVSYAQLVVTLLDVNDEK 579
+ T G D + I L+ D + V V YA++ +TL++ ND +
Sbjct: 398 FIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNR 457
Query: 580 PVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSG 639
P+FSQP Y++S+ EN GT +L + ATD D G G V + + D F LD +G
Sbjct: 458 PIFSQPL-YNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSD---DPDRFSLDKDTG 513
Query: 640 RLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIK 699
+ I+ LD E ++L ++A D G + RINV LD+NDN P F Y ++
Sbjct: 514 LIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINV--LDVNDNVPTFQKDAYVGALR 571
Query: 700 ENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR--SRFQVNAQS--GVISTRMALDREE 755
ENEP + + + ATD D N + YSI + S F ++ GVIS LD E+
Sbjct: 572 ENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQ 631
Query: 756 --KTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVG 813
L ++A D GN + VTI V D DNPP FS+ AY V EN+ G V
Sbjct: 632 ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVL 691
Query: 814 SVSASTMDLNSNISY--LITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG 871
++A+ +D + +I + + F IN +G++TT +++DRE +S Y L V A G
Sbjct: 692 FLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDG 751
Query: 872 TV-----TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNG 926
V TG VNIT+ D+NDN P + A +N+VE + AVDPD G NG
Sbjct: 752 GVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENG 811
Query: 927 MVLYSLKQNPKNLFAINEKNGTISLLGPL------DVHAGSYQIEILAS--DMGVPQLSS 978
++YS+ Q P +++N G I + D H +I+ S D G P L +
Sbjct: 812 TLVYSI-QPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKA 870
Query: 979 SVILTVYVH--DVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIA 1036
+ TV+V+ D+NDN P F L + + E P ++V A D D G NG ++Y +
Sbjct: 871 TSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMP 930
Query: 1037 EGNTGDAFGI-FPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVND 1095
G F I G + +ELDRE Y L VVASD S+T +T+ + DVND
Sbjct: 931 VGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVND 990
Query: 1096 NRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE--MVQPDFELHAISG 1153
P F Y E+ V ++ D D G N E+ Y V F +
Sbjct: 991 ETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDA 1050
Query: 1154 EITNTHQFDRESLMRRRGTAVFSFTVIATDQG-IPQPLKDQATVHVYMKDINDNAPKFLK 1212
+ DRE+ TA + + A D G + + ATV V + D+NDN P FL+
Sbjct: 1051 VVRTVVGLDRET------TAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQ 1104
Query: 1213 DFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGK 1272
Y+A++ E +L++ A+D DEG G + Y I+ GN F I ++G + +
Sbjct: 1105 SSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1164
Query: 1273 -LDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLF-VDVLENMRI 1330
LD E ++ L+++A + P+ S+ + + + D ND P F + + + E I
Sbjct: 1165 PLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGI 1224
Query: 1331 GELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNI 1390
G V V ATD DSGD + Y I + G F I +TG I LD+ET++ Y +N+
Sbjct: 1225 GTSVIVVQATDRDSGDGGLVNYRIL-SGAEGKFEIDESTGLIITVNYLDYETKTSYMMNV 1283
Query: 1391 TAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDAD 1450
+A DQ P SV I + + D F +I+EN+ +GT ++ V A+ D
Sbjct: 1284 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNL 1343
Query: 1451 INGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRY 1510
+ F ID + G I +DRE + + LTV A+D ++
Sbjct: 1344 NQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVD---- 1399
Query: 1511 ALKNVTILVTDLNDNVPM--FISQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEII 1568
+ V I V D NDN P F S +A++ +G + T+ A DPD G+NG++ + +
Sbjct: 1400 STVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLA 1459
Query: 1569 NGDT----DTFIVDRYSGDLRVASALVPSQL-IYNLIVSATDLG--PERRKSTTELTIIL 1621
+G+ + + G++ VA L +L Y L V A+D G P ++ ++TI+
Sbjct: 1460 SGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILD 1519
Query: 1622 QGLDGPVFTQP-KYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYYIVSVRCEEKTVGR 1679
+ PV P Y + E GT V+ + A G + + YYI E
Sbjct: 1520 INDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYIT-----EGNKDM 1574
Query: 1680 LFTIGRHTGIIQT-AAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPP 1738
F + R +G I T A DRE+ + +LV E + T V +T+ D NDN P
Sbjct: 1575 AFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSAT--THVYVTIVDENDNAP 1632
Query: 1739 VFPTDMLDLTVEENIGD-GSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDL 1796
+F ++ ++E + ++ + A+D DEG N VTY I++G ++FRID G +
Sbjct: 1633 MFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVI 1692
Query: 1797 IATRRLDRE-RRSKYSLLVRADDGLQ------SSDMRINITVSDVNDHTPKFSRPVYS-F 1848
A + LD E +Y+L+V A D +S + + V+D+ND+ P F R F
Sbjct: 1693 TAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPF 1752
Query: 1849 DIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTR--LLDY 1906
++ E PG V LA D DSG NG++ Y + + D G F ++P+ GV + + LD
Sbjct: 1753 EVTEGQ-PGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDR 1811
Query: 1907 EVQQYYILTVRAEDGG--GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVL 1964
E +Y LT+ A D G +T+ V +LD+NDN P+ + ++ EN PV S V
Sbjct: 1812 ETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVA 1871
Query: 1965 VFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDL 2023
+DAD G N++LT++I +G+ F ++ G++ V + LDRE Y L + V D
Sbjct: 1872 HVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDN 1931
Query: 2024 PQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-------IPENTPIDTVVFKAQATD 2076
P+ P + I L D NDN P F K TY P TP+ + A D
Sbjct: 1932 PENPRIARRDYDLLLIFLSDENDNHPLF--TKSTYQAEVMENSPAGTPLTVLNGPILALD 1989
Query: 2077 PDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGE--LDREEVSNYTLTVVATDKGQPSL 2134
D + + Y LL F I + G V + +DRE S L ++ + L
Sbjct: 1990 ADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLL 2049
Query: 2135 SSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIV 2194
+S+ +++ +LD NDN P F+ A V + EN G ++QV A D D G NG++ Y I
Sbjct: 2050 NSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIE 2109
Query: 2195 NGNTNQEFRIDSVTGAITVAK-PLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDIN 2253
G F I VTG I V +DRE+ +Y LTV ATDRG+ P + T+ V+I++ DIN
Sbjct: 2110 AG-AQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2168
Query: 2254 DFVPVFELSPYSVNVPENL--GTLPRTILQVVARDDDRGSNSKLSYVLFG---------- 2301
D P F +V+V E+ GT+ I + A D D N KL Y + G
Sbjct: 2169 DSRPEFLNPIQTVSVLESAEPGTV---IANITAIDHD--LNPKLEYHIVGIVAKDDTDRL 2223
Query: 2302 -GNEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGS-----PALTGTGTINVIV 2354
N+++AF ++ +G + V ++RE + + ++ D+ S + V V
Sbjct: 2224 VPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNV 2283
Query: 2355 DDVNDNVP---TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR------IIGGN 2405
DVNDN P F Y I E A GT ++ V A D D N ++ + G
Sbjct: 2284 LDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGY 2343
Query: 2406 SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPR 2465
Q + S G++I + +D E V SD GSP P ++ V + + D+NDN P
Sbjct: 2344 VQLE-DSSAGKVIANRTVDYEEVHWLNFTVRASDNGSP-PRAAEIPVYLEIVDINDNNPI 2401
Query: 2466 FQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAA 2525
F Y + G+ + VT TDAD G + + YSL G KF I+P G I
Sbjct: 2402 FDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSL-GDGESKFAINPTTGDIYVL 2460
Query: 2526 GPLNGASEVTFSV------HVKDGGSFPKTDSTTVTVRFVNKADF-PKVRAKEQTFMFPE 2578
L+ + + + + D S + +S V ++ ++ D P+ + + E
Sbjct: 2461 SSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYE 2520
Query: 2579 NQPVSSLVTTITGSSLRGEPMS--YYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYV 2636
N+P + V T+ + P Y G F +D +G V+ +PL + +K+
Sbjct: 2521 NEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPL--QSYEKFS 2578
Query: 2637 VWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP--FISEILENLSPR-KILTVSAM 2693
+ + A DGG PP L + V+DVNDN P+F P I I E + R + V A
Sbjct: 2579 LTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYAT 2638
Query: 2694 DKDSGPNGQLDYEIVN--GNME-NSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGS 2750
DKD G NG + Y + GN + F I+ +G I++ + LDRE + Y L + +SD G
Sbjct: 2639 DKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQ 2698
Query: 2751 P-SQSTSVKVMINILDENDNAPRF-------SQIFSAHVPENSPLGYTVTRVTTS-DEDI 2801
P T + + + D +DN P F Q VPE+SP G V VT + D D
Sbjct: 2699 PVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADE 2758
Query: 2802 GINAISRYSIM--DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDS-GWT----- 2853
G NAI Y I + F + P G +++ R L+RE + V A + WT
Sbjct: 2759 GPNAIVYYFIAAGNEEKNFHLQPD-GCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2817
Query: 2854 ----------VSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGS 2903
+V + + DIND PRF++ Y ++GS++ QV A D D G+
Sbjct: 2818 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGN 2877
Query: 2904 NGQVFYFIKSQSEYFRINATTGE 2926
N VFY I + YFR A E
Sbjct: 2878 NSLVFYSILA-IHYFRALANDSE 2899
Score = 1002 bits (2591), Expect = 0.0
Identities = 878/2890 (30%), Positives = 1368/2890 (47%), Gaps = 202/2890 (6%)
Query: 801 VVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQS 860
++ E+ +G V + A MD N + + ++ + FA+ TG + +DRE +S
Sbjct: 41 LISEDTPVGSSVTQLLAQDMD-NDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKS 99
Query: 861 FYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDP 920
+ ++ S VNI V D+NDN+P F SV + EN G IF A DP
Sbjct: 100 EFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDP 159
Query: 921 DEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAG-SYQIEILASDMGVPQ-LSS 978
D G G VLYS Q P FAI+ G ++++ LD +YQ+ + A+D + LS+
Sbjct: 160 DLGAGGSVLYSF-QPPSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLST 218
Query: 979 SVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEG 1038
L + + DV D P+F L Y + E P + + A D+D G I YTI G
Sbjct: 219 LANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSG 278
Query: 1039 NTGDAFGI-FPDGQLYIKSELDRE---LQDRYVLMVVAS----DRAVEPLSATVNVTVIL 1090
NT F + + G L + LDRE ++L V + DR + T +++
Sbjct: 279 NTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILV 338
Query: 1091 EDVNDNRPLFNSTNYTFYFEEEQRAGSFVGK-VSAVDKDFGPNGEVRYSFEMVQPDFELH 1149
D+NDN P FNS+ Y+ E + G + + VDKD N + FE+ H
Sbjct: 339 IDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKD--ENLGLNSMFEVYLVGNNSH 396
Query: 1150 -------AISGE----ITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHV 1198
++ G+ I D E++ R + F + A ++ +P + A V +
Sbjct: 397 HFIISPTSVQGKADIRIRVAIPLDYETVDR------YDFDLFA-NESVPDHV-GYAKVKI 448
Query: 1199 YMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQF 1258
+ + NDN P F + Y ++ E+ T VL V A+D D G G + Y ++ +F
Sbjct: 449 TLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFF--SDDPDRF 506
Query: 1259 AIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKS 1318
++D +G + LI +LDYE ++L I A D G +T + I++LD NDN P+F K
Sbjct: 507 SLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE--ETTGRVRINVLDVNDNVPTFQKD 564
Query: 1319 TLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTF---SISPNTGSIFLA 1375
+ EN + + ATD DS N + YSI + G++ S+ G I ++
Sbjct: 565 AYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVS 624
Query: 1376 KKLDFE--TQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENI 1433
+ LD+E + L L + A D G PP +ST+ V I V D NDNPP+F F S+VENI
Sbjct: 625 RPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENI 684
Query: 1434 PIGTSVISVTAHDPDADIN-GQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLF 1492
G +V+ + A D D GQ S II + F I+ G I T + +DRE + +
Sbjct: 685 MAGATVLFLNATDLDRSREYGQES--IIYSLEGSTQFRINARSGEITTTSLLDRETKSEY 742
Query: 1493 ELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQ----NALAADPSAVIGSVLT 1548
L V+A D V ++ + V I + D+NDN P + N + P S +T
Sbjct: 743 ILIVRAVDGGVG-HNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPP---DSDVT 798
Query: 1549 TIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASALVP--------SQLIYNLI 1600
T++A DPD G NG + Y I + ++ +G +R A++ ++L+ ++
Sbjct: 799 TVVAVDPDLGENGTLVYSI-QPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIV 857
Query: 1601 VSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYITILKEGEPIGTNVISIEAAS- 1655
VS TD G K+T+ T+ + LD P F ++ + EG P G ++ + A
Sbjct: 858 VSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDL 917
Query: 1656 PRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKS 1715
G +VS R F I +G++ T LDRE+ A Y + V A +
Sbjct: 918 DEGLNG-----LVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIA-EYQLRVVASDAG 971
Query: 1716 TAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALV 1775
T ++ + + I + D+ND P F + +++V E++ +++ L D D G NA +
Sbjct: 972 TP-TKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAEL 1030
Query: 1776 TYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDG-----LQSSDMRINI 1829
+Y I G D F + + LDRE + Y L++ A D + + +
Sbjct: 1031 SYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFV 1090
Query: 1830 TVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIF 1889
TV DVND+ P F + Y +PED G + + ATD D G G + Y + + F
Sbjct: 1091 TVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNF 1150
Query: 1890 FLNPITGVFNL-TRLLDYEVQQYYILTVRA--EDGGGQFTTIRVYFNILDVNDNPPIFSL 1946
++ G+ R LD E ++L V A D G +++RV + D+ND P+F+
Sbjct: 1151 RIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQ 1210
Query: 1947 NSYST-SLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKN-GVLKVLK 2004
YS L E +G++V+V TD D G + Y I SG G+F +D++ G++ +
Sbjct: 1211 QQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAE-GKFEIDESTGLIITVN 1269
Query: 2005 ALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL-TYIPENT 2063
LD E+++ Y + V D F S V I LL+ D F + I EN
Sbjct: 1270 YLDYETKTSYMMNVSATDQAPPFNQGFCS---VYITLLNELDEAVQFSNASYEAAILENL 1326
Query: 2064 PIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--FSIGTIDGEVRLTGELDREEVSNYT 2121
+ T + + QA D+ + K F I I G + + G +DRE+ YT
Sbjct: 1327 ALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYT 1386
Query: 2122 LTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFA-QALYKVEINENTLTGTDIIQVFAAD 2180
LTVVA D G P + S+ +V + VLD NDN+P F + V I E+ G + V A D
Sbjct: 1387 LTVVADDGG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWD 1445
Query: 2181 GDEGTNGQVRYGIVNGNTNQEFRI----DSVTGAITVAKPLDREKTPTYHLTVQATDRGS 2236
D G+NGQV + + +GN F I DS+ G + VA+PLDRE+ Y L V A+DRG+
Sbjct: 1446 PDAGSNGQVVFSLASGNIAGAFEIVTTNDSI-GEVFVARPLDREELDHYILQVVASDRGT 1504
Query: 2237 TPRTDTSTVSIVLLDINDFVPVFELSP--YSVNVPENLGTLPRTILQVVARDDDRGSNSK 2294
PR + + +LDIND PV E SP Y+V+V EN+G ++QV A D D G NS
Sbjct: 1505 PPRKKDHILQVTILDINDNPPVIE-SPFGYNVSVNENVGG-GTAVVQVRATDRDIGINSV 1562
Query: 2295 LSYVLFGGNEDNAFTLSA-SGELGVTQSL-DRETKERFVLMITATDSGSPALTGTGTINV 2352
LSY + GN+D AF + SGE+ + DRE + + L+ T D G+P L+ T + V
Sbjct: 1563 LSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYV 1622
Query: 2353 IVDDVNDNVPTFASKAYFTTIPEDAPT-GTDVLLVNASDADASKNAVIR--IIGGN--SQ 2407
+ D NDN P F Y + E T T ++ + A D D N + I+ GN +
Sbjct: 1623 TIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNT 1682
Query: 2408 FTINPSTGQIITSALLDRE-TKDNYTLVVVCSDAGS--PEPLSSSTSVLVTVTDVNDNPP 2464
F I+ G I + LD E + YTL+V +D L+S+T+VLV V D+NDN P
Sbjct: 1683 FRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVP 1742
Query: 2465 RFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLRGAIM 2523
F + PG V+ D D GPN ++ YS+ G +F I P+ G +
Sbjct: 1743 TFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLR 1802
Query: 2524 AAGPLNGASEV----TFSVHVKDGGSFPKTDSTTVTVRFVNKADF-PKVRAKEQTFMFPE 2578
+ E ++ +D G P + + V +R ++ D P + E
Sbjct: 1803 VRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISE 1862
Query: 2579 NQPVSSLVTTITGSSLRG---EPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKY 2635
N PVSS V + S +++ I +GN F I+ TG V++++PLD E+I +Y
Sbjct: 1863 NSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEY 1922
Query: 2636 VVWIEARDGGFPPFSS---YEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVS- 2691
+ I +D P + Y+ L I + D NDN P+F + + +E++EN LTV
Sbjct: 1923 KLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLN 1982
Query: 2692 ----AMDKDSGPNGQLDYEIVNGNMENSFSINHATG--EIRSVRPLDREKVSHYVLTIKS 2745
A+D D + Y+++ G F IN +TG +RS +DRE S +L +
Sbjct: 1983 GPILALDADQDIYAVVTYQLL-GAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLL 2041
Query: 2746 SDKGSPSQSTSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGIN 2804
+ +++ ++I ILD+NDN P FS + H+ EN P G++V +VT +DED G+N
Sbjct: 2042 LAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLN 2101
Query: 2805 AISRYSI-MDASLPFTINPSTGDIVISRP-LNREDTDRYRIRVSAHDSGWTVSTD---VT 2859
Y I A F I+ TG I + ++RE+ + YR+ V A D G + VT
Sbjct: 2102 GELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVT 2161
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFI-------- 2911
I + DIND+ P F + E E G+ + + A D D N ++ Y I
Sbjct: 2162 ILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHD--LNPKLEYHIVGIVAKDD 2219
Query: 2912 -----KSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSL-IS 2965
+Q + F +N TG + K + + V + V + S I +SD + S+ +
Sbjct: 2220 TDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYE-VTL---SVIDNASDLPERSVSVP 2275
Query: 2966 ETTVTINIVDSNDNAPQFLK---SKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYF 3022
+T+N++D NDN PQF + Y + + GT LI V A+D D GLN V Y
Sbjct: 2276 NAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDP-DKGLNGLVTYT 2334
Query: 3023 ISNDNHLGKFKLDNDTGWISVASSLISDLNQNFF-ITVTAKDKGNPPLSSQATVHITVTE 3081
+ + G +L++ + +A+ + ++ TV A D G+PP +++ V++ + +
Sbjct: 2335 LLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVD 2394
Query: 3082 ENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINS 3141
N + P F Q + E +G+I+ TV+A D D+ LI+YS+ G E FAIN
Sbjct: 2395 INDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDG--ESKFAINP 2452
Query: 3142 STGILTLAKALDYELCQKHEMTISAIDG-GWVA---RTGYCSVTVNVIDVNDNSPVFLSD 3197
+TG + + +LD E + +T A D G VA R V + V+DVND P F
Sbjct: 2453 TTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKP 2512
Query: 3198 DYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLD 3257
+ +V EN P+GT+VI + ATD D G N + Y+++ + F +D ++G++TTQ L
Sbjct: 2513 QFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPL- 2571
Query: 3258 FETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFV--SKLYYFEISEAAPKGT 3315
++ + + LTV A + + + +++ N+ P FV I E P +
Sbjct: 2572 -QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRS 2630
Query: 3316 IVGEVFASDRDLGTDGEVHYLIF---GNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
V EV+A+D+D G +G V Y GN + F I+ +G I + LDRE + SL
Sbjct: 2631 NVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLI 2690
Query: 3373 VLAKNFGS-IRGADIDEVTVNVTVLDAND-----PPIFTLNIYSVQISEGVPIGTHVTFV 3426
++A + G + + + V + +D N+ PP + + + E P GT V V
Sbjct: 2691 LVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNV 2750
Query: 3427 S-AFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVD- 3484
+ A D+D P+ + YFI +GNE F + P G + V +LDRE I++ V A
Sbjct: 2751 TGAVDADEGPN-AIVYYFIAAGNEEKNFHLQPD-GCLLVLRDLDREREAIFSFIVKASSN 2808
Query: 3485 -SGTPSATGSASL-----------LVTLEDINDNGPMLTVSE--GEVMENKRPGTLVMTL 3530
S TP S +L V LEDIND P T +E V + + G+ ++ +
Sbjct: 2809 RSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQV 2868
Query: 3531 QSTDPDLPPN 3540
+ D D+ N
Sbjct: 2869 LALDADIGNN 2878
Score = 1002 bits (2591), Expect = 0.0
Identities = 875/2925 (29%), Positives = 1354/2925 (46%), Gaps = 209/2925 (7%)
Query: 592 VVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREE 651
+ E+ P G+ + L A D D N + F + E R F ++P +G + LDRE
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEEASR-FFAVEPDTGVVWLRQPLDRET 97
Query: 652 QAFYSLLVLATDLGSPPQSSMAR-INVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT 710
++ +++ +D Q + R +N+ + D+NDN+P F+ Y I EN P G+ I
Sbjct: 98 KSEFTVEFSVSD----HQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFI 153
Query: 711 VSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGN 770
V+ATDPDLG G+V YS + F +++ G+++ LD E AYQL + ATD
Sbjct: 154 VNATDPDLGAGGSVLYSFQPPSQF-FAIDSARGIVTVIRELDYETTQAYQLTVNATDQDK 212
Query: 771 LQSPNQ-AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNS--NIS 827
+ + A + I + D QD P+F + YS ++E+ G V ++A D I
Sbjct: 213 TRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIG 272
Query: 828 YLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGD----------T 877
Y I +G+ +FA++ ++G LT ++DRE + ++ GT D T
Sbjct: 273 YTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTT 332
Query: 878 MVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSI-FQAKAVDPDE--GVNGMVLYSLKQ 934
NI V D+NDN+P F + SV + E Q G ++ + VD DE G+N M L
Sbjct: 333 TFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVG 392
Query: 935 NPKNLFAIN------EKNGTISLLGPLDVHA-GSYQIEILASDMGVPQLSSSVILTVYVH 987
N + F I+ + + I + PLD Y ++ A++ VP + + +
Sbjct: 393 NNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANE-SVPDHVGYAKVKITLI 451
Query: 988 DVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIF 1047
+ NDN P+F Q Y ++L E+ V + V A+D D+G GE++Y ++ D F +
Sbjct: 452 NENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDP--DRFSLD 509
Query: 1048 PD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYT 1106
D G + + + LD EL R+ L ++A D E + V + V+ DVNDN P F Y
Sbjct: 510 KDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVL--DVNDNVPTFQKDAYV 567
Query: 1107 FYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQP-----DFELHAISGEITNTHQF 1161
E + + + + ++ A D+D PN ++ YS D L+ G I+ +
Sbjct: 568 GALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPL 627
Query: 1162 DRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISE 1221
D E + + TV+A D G P PL V + + D NDN P F K Y ++ E
Sbjct: 628 DYEQI----SNGLIYLTVMAMDAGNP-PLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVE 682
Query: 1222 SAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAY 1281
+ VL ++A+D+D I QF I++ SG++T LD E Y
Sbjct: 683 NIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEY 742
Query: 1282 SLVIQAVDSGTIPLNST--CTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTA 1339
L+++AVD G T T+NI +LD NDN P++ + +++++E V++V A
Sbjct: 743 ILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVA 802
Query: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKL-------DFETQSLYKLNITA 1392
D D G+N L YSI N +S++ TG I + E + + K+ ++
Sbjct: 803 VDPDLGENGTLVYSIQPPNKF--YSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSV 860
Query: 1393 KDQGRPPRSSTMSVVIHVR--DFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDAD 1450
D GRPP +T S + V D NDN P+F ++E IP G S+ V A D D
Sbjct: 861 TDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEG 920
Query: 1451 INGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRY 1510
+NG +SY + MPR + F I+ G + T E+DRE ++L V A+D P ++
Sbjct: 921 LNGLVSYRMPVGMPRMD-FLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKS--- 976
Query: 1511 ALKNVTILVTDLNDNVPMFI-SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIIN 1569
+ +TI V D+ND P F + ++ + + D D G N E+ Y I
Sbjct: 977 STSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITG 1036
Query: 1570 GDTD-TFIVDRYSGDLRVASALV-PSQLIYNLIVSATDLGPERRKSTTELTIILQGLD-- 1625
G+ D F V +R L + Y LI+ A D GP ++ T T+ + LD
Sbjct: 1037 GNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVN 1096
Query: 1626 --GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTI 1683
P+F Q Y + E P G +++ ++A E +Y R G F I
Sbjct: 1097 DNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWY----RILHGNHGNNFRI 1152
Query: 1684 GRHTGIIQTAAI-LDREQGAC-LYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFP 1741
G++ LDRE+ + + +V+ Y + P V + ++DIND PVF
Sbjct: 1153 HVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLG---PMRSSVRVIVYVEDINDEAPVFT 1209
Query: 1742 TDMLD-LTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATR 1800
L + E G G+ ++ + A D D G LV Y I+SGA+ F ID +G +I
Sbjct: 1210 QQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVN 1269
Query: 1801 RLDRERRSKYSLLVRADDGLQSSDM---RINITVSDVNDHTPKFSRPVYSFDIPEDTIPG 1857
LD E ++ Y + V A D + + IT+ + D +FS Y I E+ G
Sbjct: 1270 YLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALG 1329
Query: 1858 SLVAAILATDDDSGVNGEITYIVN---EDDEDGIFFLNPITGVFNLTRLLDYEVQQYYIL 1914
+ + + A D+ +ITY N +F ++ ITGV + L+D E +Y L
Sbjct: 1330 TEIVRVQAYSIDN--LNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTL 1387
Query: 1915 TVRAEDGGGQF-TTIRVYFNILDVNDNPPIFSLNSYST-SLMENLPVGSTVLVFNVTDAD 1972
TV A+DGG + +T++VY +LD NDN P F S S S+ E+ PVG V D D
Sbjct: 1388 TVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPD 1447
Query: 1973 DGINSQLTYSIASGDSLGQFTV----DKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPA 2028
G N Q+ +S+ASG+ G F + D G + V + LDRE Y L V D P
Sbjct: 1448 AGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPR 1507
Query: 2029 SRFTSTAQVSIILLDVNDNPPTFLSP--KLTYIPENTPIDTVVFKAQATDPDSGPNSYIE 2086
+ + + +LD+NDNPP SP + EN T V + +ATD D G NS +
Sbjct: 1508 KK---DHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLS 1564
Query: 2087 YTLLNPLGNK---FSIGTIDGEVRLT-GELDREEVSNYTLTVVATDKGQPSLSSSTEVVV 2142
Y + GNK F + I GE+ DRE S Y L D+G P+LS++T V V
Sbjct: 1565 YYITE--GNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYV 1622
Query: 2143 MVLDINDNNPIFAQALYKVEINENTLT-GTDIIQVFAADGDEGTNGQVRYGIVNGNTNQE 2201
++D NDN P+F Q Y+V ++E T T +I + A D DEG NG V Y IV GN
Sbjct: 1623 TIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNT 1682
Query: 2202 FRIDSVTGAITVAKPLDREKTP-TYHLTVQATDRG---STPRTDTSTVSIVLLDINDFVP 2257
FRID G IT AK LD E + Y L V ATD+ S T T+TV + + DIND VP
Sbjct: 1683 FRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVP 1742
Query: 2258 VFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGEL 2316
F Y G + +A D D G N ++ Y + G+ F +S G L
Sbjct: 1743 TFPRD-YEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVL 1801
Query: 2317 GVTQS--LDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIP 2374
V + LDRET + L I A D G P L+ T + + V D+NDN P + TI
Sbjct: 1802 RVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITIS 1861
Query: 2375 EDAPTGTDVLLVNASDADASKNA--VIRIIGGNSQ--FTINPSTGQIITSALLDRETKDN 2430
E++P + V V ASDAD+ NA I GN + F IN +TG + + LDRE
Sbjct: 1862 ENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPE 1921
Query: 2431 YTLVVVCSDAGSPEPLSSSTS--VLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFA- 2487
Y L + D ++ +L+ ++D NDN P F Y + + G+ +
Sbjct: 1922 YKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVL 1981
Query: 2488 ---VTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHV---- 2540
+ DAD + + Y L G S F I+ G + + E FS +
Sbjct: 1982 NGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREA-FSPPILELL 2040
Query: 2541 ---KDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITG----SS 2593
+D G T +T+ N + P T EN P V +T S
Sbjct: 2041 LLAEDIGLLNSTAHLLITILDDND-NRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSG 2099
Query: 2594 LRGEPMSYYIASGNLGNTFQIDQLTGQVSISQP-LDFEKIQKYVVWIEARDGGFPPFSSY 2652
L GE + Y I +G + F I +TG + + +D E+ + Y + + A D G P S
Sbjct: 2100 LNGE-LVYRIEAG-AQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGT 2157
Query: 2653 EKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILT-VSAMDKDSGPNGQLDYEIVN-- 2709
+ I + D+ND+ P F +LE+ P ++ ++A+D D P +L+Y IV
Sbjct: 2158 AIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNP--KLEYHIVGIV 2215
Query: 2710 ---------GNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGS--PSQSTSV- 2757
N E++F++N TG + P++RE V+ Y +T+ D S P +S SV
Sbjct: 2216 AKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVP 2275
Query: 2758 --KVMINILDENDNAPRFSQI----FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSI 2811
K+ +N+LD NDN P+F + + E + G T+ V D D G+N + Y++
Sbjct: 2276 NAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTL 2335
Query: 2812 MDASLPFTI---NPSTGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDI 2865
+D P + + S G ++ +R ++ E+ V A D+G V + + DI
Sbjct: 2336 LDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDI 2395
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTG 2925
NDN P F + SY E +G+ + V ATD D G+ + Y + F IN TTG
Sbjct: 2396 NDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTG 2455
Query: 2926 EIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLK 2985
+I+ L + + + + + +S+R + S+ V I ++D ND PQF K
Sbjct: 2456 DIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSV----QVVIQVLDVNDCRPQFSK 2511
Query: 2986 SKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVAS 3045
++ T V +N GT +I + A D +D G N E+ Y + + F +D D+G ++
Sbjct: 2512 PQFSTSVYENEPAGTSVITMMATD-QDEGPNGELTYSLEGPG-VEAFHVDMDSGLVTTQR 2569
Query: 3046 SLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSAT--IPESHS 3103
L S + F +TV A D G PPL + + V + N + P F + I E
Sbjct: 2570 PLQS--YEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIP 2627
Query: 3104 IGSIVRTVSARDRDAAMNGLIKYSI--SSGNEEG-IFAINSSTGILTLAKALDYELCQKH 3160
+ S V V A D+D +NG ++YS ++GN + F I+ +G++ A+ LD E +
Sbjct: 2628 LRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVY 2687
Query: 3161 EMTISAIDGGW-VARTGYCSVTVNVIDVNDNSPVFL-----SDDY-FPTVLENAPSGTTV 3213
+ + A D G V + V + D++DN P+F+ S Y TV E++P GT V
Sbjct: 2688 SLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLV 2747
Query: 3214 IHLN-ATDADSGTNAVIAYTVQSSDSDL-FVIDPNTGVITTQGFLDFETKQSYHLTVKAF 3271
++ A DAD G NA++ Y + + + + F + P+ G + LD E + + VKA
Sbjct: 2748 GNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPD-GCLLVLRDLDREREAIFSFIVKAS 2806
Query: 3272 N----------VPDEERCSFAT---VNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVG 3318
+ P + + T V + L+ N+ PRF Y ++ A G+ +
Sbjct: 2807 SNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELI 2866
Query: 3319 EVFASDRDLGTDGEVHYLIFGNSRKKGF-QINKKTGQIYVSGILD 3362
+V A D D+G + V Y I + ++ GQ++ G +D
Sbjct: 2867 QVLALDADIGNNSLVFYSILAIHYFRALANDSEDVGQVFTMGSMD 2911
Score = 976 bits (2522), Expect = 0.0
Identities = 873/2919 (29%), Positives = 1373/2919 (47%), Gaps = 229/2919 (7%)
Query: 259 VPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP--FQMDPETGLITVREPLDFEAR 316
+ ED VGSSV Q+ A D D N + + + E F ++P+TG++ +R+PLD E +
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK 98
Query: 317 RQYSLTVQAMD-RGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGT 375
++++ D +GV +T + IQ+ DVNDN P F P + R + EN VGT
Sbjct: 99 SEFTVEFSVSDHQGV--ITRKVN--IQVGDVNDNAPT--FHNQPYSVR---IPENTPVGT 149
Query: 376 VVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYN 435
+ ++ TD D A SV + F + S++ ++ V LD E +Y
Sbjct: 150 PIFIVNATDPDLGAGG---SVLYSFQPPSQFFAIDSAR----GIVTVIRELDYETTQAYQ 202
Query: 436 LTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVS 495
LTV+ +D P S++A+L I + D+ D P+F Y N+ E +PPG+ V
Sbjct: 203 LTVNATDQDKTRP------LSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVR 256
Query: 496 GISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE---LASQIVLNI 552
I+A D D G + Y+IVSGN F + SG++T +G LDRE + +L +
Sbjct: 257 IITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTL--NGLLDRENPLYSHGFILTV 314
Query: 553 SARDQGVHPKVSYAQLVVT----LLDVNDEKPVFSQPEGYDVSVVENAPTGTEL-LMLRA 607
+ S A + T ++D+ND P F+ E Y V++ E A G L L ++
Sbjct: 315 KGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE-YSVAITELAQVGFALPLFIQV 373
Query: 608 TDGDLGDNGTVRFSLQEAETDRRSFRLDPVSG------RLSTISSLDREEQAFYSLLVLA 661
D D F + + F + P S R+ LD E Y + A
Sbjct: 374 VDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFA 433
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+ P A++ ++L++ NDN P+F Y + EN G+ + TV ATD D GT
Sbjct: 434 NE-SVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTF 492
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V Y S D RF ++ +G+I LD E + L I+A DGG ++ + V I
Sbjct: 493 GEVSYFFS-DDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGR--VRI 549
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL--NSNISYLITTGDQKGMF 839
VLD DN P F + AY + EN + + A+ D N+ I+Y I + G +
Sbjct: 550 NVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSY 609
Query: 840 ---AINQVTGQLTTANVIDREEQS----FYQLKVVASGGTVTGDTM-VNITVKDLNDNSP 891
++ + G ++ + +D E+ S + + + +G T+ V I V D NDN P
Sbjct: 610 FDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPP 669
Query: 892 HFLQAIESVNVVENWQAGHSIFQAKAVDPD---EGVNGMVLYSLKQNPKNLFAINEKNGT 948
F + V+VVEN AG ++ A D D E ++YSL+ + + F IN ++G
Sbjct: 670 TFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQ--FRINARSGE 727
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVH--DVNDNSPVFDQLSYEVTL 1005
I+ LD S Y + + A D GV + I TV + D+NDN P + Y + L
Sbjct: 728 ITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINL 787
Query: 1006 SESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDR 1065
E P +S V A D D G NG + Y+I N + + LDRE D
Sbjct: 788 VEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDP 847
Query: 1066 Y------VLMVVASDRAVEPLSATVNVTVI--LEDVNDNRPLFNSTNYTFYFEEEQRAGS 1117
+ ++V +D PL AT + TV L D+NDN P F + + E AG
Sbjct: 848 HEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGV 907
Query: 1118 FVGKVSAVDKDFGPNGEVRYSFEMVQP--DFELHAISGEITNTHQFDRESLMRRRGTAVF 1175
+ +V A+D D G NG V Y + P DF +++ SG + T + DRE + A +
Sbjct: 908 SIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERI------AEY 961
Query: 1176 SFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSAS 1235
V+A+D G P +T+ +++ D+ND P F Y ++SE +V+ ++ +
Sbjct: 962 QLRVVASDAGTPTK-SSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCT 1020
Query: 1236 DVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPL 1295
D D G N + Y I GN + +F++ V + LD E T AY L+++A+D+G +
Sbjct: 1021 DNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGK 1080
Query: 1296 --NSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYS 1353
T T+ + +LD NDN P F +S+ V E++ G + + ATD+D G+ ++Y
Sbjct: 1081 RHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYR 1140
Query: 1354 ITGTNNHGTFSISPNTGSIFLA-KKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
I N+ F I + G + + LD E S + L + A + P S++ V+++V D
Sbjct: 1141 ILHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVED 1200
Query: 1413 FNDNPPSFPPGDIFK-SIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
ND P F + + E IGTSVI V A D D+ G ++Y I+ F I
Sbjct: 1201 INDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAE--GKFEI 1258
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
DE G I T +D E + + V A DQA P + + +T+L +L++ V +
Sbjct: 1259 DESTGLIITVNYLDYETKTSYMMNVSATDQAPPF-NQGFCSVYITLL-NELDEAVQFSNA 1316
Query: 1532 QNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDT-----FIVDRYSGDLRV 1586
A + +G+ + + A D +I Y N T T F +D +G + V
Sbjct: 1317 SYEAAILENLALGTEIVRVQAYSIDN--LNQITYR-FNAYTSTQAKALFKIDAITGVITV 1373
Query: 1587 ASALVPSQL--IYNLIVSATDLGPERRKSTTELTIILQGLDGPV---FTQPKYITILKEG 1641
LV + Y L V A D GP+ + +L D FT ++I E
Sbjct: 1374 -QGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI-PED 1431
Query: 1642 EPIGTNVISIEAASP-RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQ 1700
P+G V +++A P GS V + + S + T G + A LDRE+
Sbjct: 1432 CPVGQRVATVKAWDPDAGSNGQVVFSLASGNI--AGAFEIVTTNDSIGEVFVARPLDREE 1489
Query: 1701 GACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDM-LDLTVEENIGDGSKI 1759
Y++ V A ++ T PR + +++T+ DINDNPPV + +++V EN+G G+ +
Sbjct: 1490 -LDHYILQVVASDRGTP-PRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAV 1547
Query: 1760 MQLTAMDADEGANALVTYTIISGADD-SFRIDPESGDLIATRRL--DRERRSKYSLLVRA 1816
+Q+ A D D G N++++Y I G D +FR+D SG+ IATR DRER+S Y L+
Sbjct: 1548 VQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGE-IATRPAPPDRERQSFYHLVATV 1606
Query: 1817 DD---GLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPE--DTIPGSLVAAILATDDDSG 1871
+D S+ + +T+ D ND+ P F +P Y + E DT+ SL+ I A D D G
Sbjct: 1607 EDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLI-TIQALDLDEG 1665
Query: 1872 VNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQ-YYILTVRAED-----GGGQF 1925
NG +TY + + F ++ GV + LDYE+ Y L V A D
Sbjct: 1666 PNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLT 1725
Query: 1926 TTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIAS 1985
+T V N+ D+NDN P F + + G V F D D G N Q+ YSI
Sbjct: 1726 STTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMD 1785
Query: 1986 GDSLGQFTVDK-NGVLKVLK--ALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILL 2042
GD LG+F + GVL+V K LDRE+ +FYNL + D P S ST V I +L
Sbjct: 1786 GDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLS---STMLVGIRVL 1842
Query: 2043 DVNDNPPTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FS 2098
D+NDN P L+ P I EN+P+ + V A+D DSG N+ + + + GN+ F
Sbjct: 1843 DINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNI--TAGNRERAFF 1900
Query: 2099 IGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTE---VVVMVLDINDNNPIFA 2155
I G V + LDRE + Y LT+ D + + + +++ + D NDN+P+F
Sbjct: 1901 INATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFT 1960
Query: 2156 QALYKVEINENTLTGTDII----QVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAI 2211
++ Y+ E+ EN+ GT + + A D D+ V Y ++ G + F I+S TG +
Sbjct: 1961 KSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLL-GAQSGLFDINSSTGVV 2019
Query: 2212 TVAKP--LDRE--KTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVN 2267
TV +DRE P L + A D G T+ + I +LD ND P F + +V+
Sbjct: 2020 TVRSGVIIDREAFSPPILELLLLAEDIGLL--NSTAHLLITILDDNDNRPTFSPATLTVH 2077
Query: 2268 VPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGV-TQSLDRET 2326
+ EN ++LQV A D+D G N +L Y + G +D +G + V ++DRE
Sbjct: 2078 LLENCPP-GFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREE 2136
Query: 2327 KERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLV 2386
+E + L + ATD G+ L+GT + +++DD+ND+ P F + ++ E A GT + +
Sbjct: 2137 QESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANI 2196
Query: 2387 NASDADASKNAVIRIIG-------------GNSQFTINPSTGQIITSALLDRETKDNYTL 2433
A D D + I+G F +N +TG ++ + ++RE Y +
Sbjct: 2197 TAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEV 2256
Query: 2434 VVVCSDAGSPEPLSS----STSVLVTVTDVNDNPPRFQHHP---YVTHIPSPTLPGSFVF 2486
+ D S P S + + V V DVNDN P+F+ Y+ I PG+ +
Sbjct: 2257 TLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLI 2316
Query: 2487 AVTVTDADIGPNSELHYSLSGRNSEKF--HIDPLRGAIMAAGPLN--GASEVTFSVHVKD 2542
AV D D G N + Y+L + D G ++A ++ + F+V D
Sbjct: 2317 AVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASD 2376
Query: 2543 GGSFPKTDSTTVTVRFV----NKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEP 2598
GS P+ V + V N F + +E F E+ PV +++ T+T + +
Sbjct: 2377 NGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVF---EDVPVGTIILTVTATD--ADS 2431
Query: 2599 MSYYIASGNLG---NTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYE-- 2653
++ + +LG + F I+ TG + + LD EK Y++ A+D S+
Sbjct: 2432 GNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRREN 2491
Query: 2654 --KLDITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMDKDSGPNGQLDYEIVNG 2710
++ I VLDVND P F + F + + EN + ++T+ A D+D GPNG+L Y +
Sbjct: 2492 SVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGP 2551
Query: 2711 NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNA 2770
+E +F ++ +G + + RPL + + LT+ ++D G P + +++ ++D NDN
Sbjct: 2552 GVE-AFHVDMDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNR 2608
Query: 2771 PRFSQIFSA---HVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLP-----FTINP 2822
P F + + H+ E PL V V +D+D G+N RYS + + F I+P
Sbjct: 2609 PVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDP 2668
Query: 2823 STGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTD----VTIFVTDINDNAPRFSRTS-- 2876
+G I ++ L+RE Y + + A D G V + + + + DI+DN P F R
Sbjct: 2669 ISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKG 2728
Query: 2877 ----YYLDCPELTEIGSKVTQVF-ATDPDEGSNGQVFYFIKSQSEYFRIN-ATTGEIFNK 2930
L PE + G+ V V A D DEG N V+YFI + +E + G +
Sbjct: 2729 SPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCLLVL 2788
Query: 2931 QILKYQNVTGFSNVNINRHSFIVTSSDRGKP---SLISETT---VTINIVDSNDNAPQFL 2984
+ L + FS + + S + RG L+++ T V + + D ND P+F
Sbjct: 2789 RDLDREREAIFSFI-VKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFT 2847
Query: 2985 KSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFI 3023
K++Y V + KVG++LI+V A+ D D G NS V Y I
Sbjct: 2848 KAEYTAGVATDAKVGSELIQVLAL-DADIGNNSLVFYSI 2885
Score = 970 bits (2507), Expect = 0.0
Identities = 855/2630 (32%), Positives = 1249/2630 (47%), Gaps = 209/2630 (7%)
Query: 51 VLEEQPPGTLVGTIQT------RP---GFTYRLSESHALFAINSSTGALYTTSTIDRES- 100
+ E PPGT V I RP G+T ++++FA++ +G L +DRE+
Sbjct: 245 IYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENP 304
Query: 101 ---------LPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSG 151
+ +N S T T +LV D+NDNAP F V E + G
Sbjct: 305 LYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVG 364
Query: 152 RQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEG-AFLHLVSKGGLDR 210
+ L + G++ + GN + F + T S +G A + + LD
Sbjct: 365 FALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPT---SVQGKADIRIRVAIPLDY 421
Query: 211 EVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL 270
E +Y + ++ P GY +V +T+ + NDN P+F Y + E+ VG+SVL
Sbjct: 422 ETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVL 480
Query: 271 QVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGV 330
V A D D GT ++ Y D+ F +D +TGLI + LD+E ++++LT+ A D G
Sbjct: 481 TVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGG 540
Query: 331 PSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
TGR I +LDVNDN P F + ++ EN T + L TD DSP
Sbjct: 541 EETTGRVR--INVLDVNDNVPT-----FQKDAYVGALRENEPSVTQLVRLRATDEDSP-P 592
Query: 391 NGNISVQILGGNE-QRHFEVQSSKVPNLSLIKVASALDRERIPS--YNLTVSVSDNYGAP 447
N I+ I+ + +F++ S +I V+ LD E+I + LTV D G P
Sbjct: 593 NNQITYSIVSASAFGSYFDI--SLYEGYGVISVSRPLDYEQISNGLIYLTVMAMD-AGNP 649
Query: 448 PGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLN 507
P +S + I V D ND+PP FS+ Y V++ E G+ V ++ATD D
Sbjct: 650 P------LNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSRE 703
Query: 508 ANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGV--HPKVSY 565
I S G F I+ SG +TT S LDRE S+ +L + A D GV + K
Sbjct: 704 YGQESIIYSLEGSTQFRINARSGEITTTSL--LDRETKSEYILIVRAVDGGVGHNQKTGI 761
Query: 566 AQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEA 625
A + +TLLD+ND P + Y +++VE P +++ + A D DLG+NGT+ +S+Q
Sbjct: 762 ATVNITLLDINDNHPTWKDAP-YYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQ-- 818
Query: 626 ETDRRSFRLDPVSGRL-STISSLDREE------QAFYSLLVLATDLGSPP--QSSMARIN 676
+ + L+ +G++ +T + LDRE + ++V TD G PP +S A +
Sbjct: 819 -PPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVF 877
Query: 677 VSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAG-DRSR 735
V+LLD+NDN P F + + A + E P G I V A D D G NG V Y + G R
Sbjct: 878 VNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMD 937
Query: 736 FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQ 795
F +N+ SGV+ T LDRE YQL++VA+D G + + +TI VLD D P F
Sbjct: 938 FLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFP 997
Query: 796 VAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTTANV 853
Y+ V E+V + V ++ + D LN+ +SY IT G+ G F++ + T
Sbjct: 998 AVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVG 1057
Query: 854 IDREEQSFYQLKVVA-----SGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQA 908
+DRE + Y L + A G TG V +TV D+NDN P FLQ+ +V E+
Sbjct: 1058 LDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPE 1117
Query: 909 GHSIFQAKAVDPDEGVNGMVLYS-LKQNPKNLFAINEKNGTISLLG--PLDVHAGSYQIE 965
GHSI Q KA D DEG G V Y L N N F I+ NG + + G PLD S +
Sbjct: 1118 GHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLL-MRGPRPLDRERNSSHVL 1176
Query: 966 IL-ASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSY-EVTLSESEPVNSRFFKVQASDK 1023
I+ A + + + SSV + VYV D+ND +PVF Q Y + L E+ + + VQA+D+
Sbjct: 1177 IVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDR 1236
Query: 1024 DSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSAT 1083
DSG G + Y I G G G + + LD E + Y++ V A+D+A
Sbjct: 1237 DSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGF 1296
Query: 1084 VNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE--- 1140
+V + L + D F++ +Y E G+ + +V A D ++ Y F
Sbjct: 1297 CSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSID--NLNQITYRFNAYT 1354
Query: 1141 --MVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHV 1198
+ F++ AI+G IT DRE ++ TV+A D G K +TV V
Sbjct: 1355 STQAKALFKIDAITGVITVQGLVDREK------GDFYTLTVVADDGG----PKVDSTVKV 1404
Query: 1199 YMK--DINDNAPKFLKDFYQ---ATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGN 1253
Y+ D NDN+P+F DF +I E +V V A D D G+NG + +S+ GN
Sbjct: 1405 YITVLDENDNSPRF--DFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGN 1462
Query: 1254 EERQFAIDSTS---GQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDEND 1310
F I +T+ G+V + LD E Y L + A D GT P L + ILD ND
Sbjct: 1463 IAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDIND 1522
Query: 1311 NTPSFPKSTLF-VDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNT 1369
N P + V V EN+ G V V ATD D G N+ L Y IT N F + +
Sbjct: 1523 NPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRIS 1582
Query: 1370 GSIFL-AKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKS 1428
G I D E QS Y L T +D+G P S+T V + + D NDN P F ++
Sbjct: 1583 GEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPH-YEV 1641
Query: 1429 IVENIP--IGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDR 1486
+++ P + TS+I++ A D D NG ++Y I+ N F ID G I E+D
Sbjct: 1642 LLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAG-NIVNTFRIDRHMGVITAAKELDY 1700
Query: 1487 EFAN-LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAAD-PSAVIG 1544
E ++ + L V A DQ + R + V + V D+NDNVP F + G
Sbjct: 1701 EISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPG 1760
Query: 1545 SVLTTIMAADPDEGANGEIEYEIINGD-TDTFIVDRYSGDLRVASALVPSQ---LIYNLI 1600
+ T +A D D G NG++EY I++GD F++ G LRV + + YNL
Sbjct: 1761 PRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLT 1820
Query: 1601 VSATDLGPERRKSTTELTIILQGL---DGPVFTQPKYITILKEGEPIGTNVISIEAA-SP 1656
+ A D G ST + I + + D + P ITI E P+ + V + A+ +
Sbjct: 1821 ICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITI-SENSPVSSFVAHVLASDAD 1879
Query: 1657 RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKST 1716
G A + + I + E R F I TGI+ LDRE+ L +++ +
Sbjct: 1880 SGCNARLTFNITAGNRE-----RAFFINATTGIVTVNRPLDRERIPEYKL--TISVKDNP 1932
Query: 1717 AFPRTQRAEVE---ITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLT----AMDADE 1769
PR R + + I L D NDN P+F V EN G+ + L A+DAD+
Sbjct: 1933 ENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQ 1992
Query: 1770 GANALVTYTIISGADDSFRIDPESGDLIATRR----LDRERRSK--YSLLVRADD-GLQS 1822
A+VTY ++ F I+ +G + T R +DRE S LL+ A+D GL +
Sbjct: 1993 DIYAVVTYQLLGAQSGLFDINSSTG--VVTVRSGVIIDREAFSPPILELLLLAEDIGLLN 2050
Query: 1823 SDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE 1882
S + IT+ D ND+ P FS + + E+ PG V + ATD+DSG+NGE+ Y +
Sbjct: 2051 STAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEA 2110
Query: 1883 DDEDGIFFLNPITGVFNL-TRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNIL--DVND 1939
+D F ++ +TGV + +D E Q+ Y LTV A D G + IL D+ND
Sbjct: 2111 GAQDR-FLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIND 2169
Query: 1940 NPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIAS-----------GDS 1988
+ P F + S++E+ G+ ++ N+T D +N +L Y I +
Sbjct: 2170 SRPEFLNPIQTVSVLESAEPGT--VIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQ 2227
Query: 1989 LGQFTVDKN-GVLKVLKALDRESQSFYNLVVQV----HDLPQIPASRFTSTAQVSIILLD 2043
F V+ N G + V ++RE + Y + + V DLP+ S A++++ +LD
Sbjct: 2228 EDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVS--VPNAKLTVNVLD 2285
Query: 2044 VNDNPPTFLSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKF 2097
VNDN P F +TY I E T + A DPD G N + YTLL+ P G
Sbjct: 2286 VNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQ 2345
Query: 2098 SIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
+ G+V +D EEV TV A+D G P ++ V + ++DINDNNPIF Q
Sbjct: 2346 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2405
Query: 2158 LYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPL 2217
Y+ + E+ GT I+ V A D D G + Y + G+ +F I+ TG I V L
Sbjct: 2406 SYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSL--GDGESKFAINPTTGDIYVLSSL 2463
Query: 2218 DREKTPTYHLTVQATDR----GSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPEN-- 2271
DREK Y LT A D S R ++ V I +LD+ND P F +S +V EN
Sbjct: 2464 DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEP 2523
Query: 2272 LGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFV 2331
GT +++ ++A D D G N +L+Y L G + AF + L VT ++ E+F
Sbjct: 2524 AGT---SVITMMATDQDEGPNGELTYSLEGPGVE-AFHVDMDSGL-VTTQRPLQSYEKFS 2578
Query: 2332 LMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTT--IPEDAPTGTDVLLVNAS 2389
L + ATD G P L GT + V V DVNDN P F T I E+ P ++V V A+
Sbjct: 2579 LTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYAT 2638
Query: 2390 DADASKNAVIRI----IGGNSQ---FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGS 2442
D D N +R GN F I+P +G I T+ LDRE++ Y+L++V SD G
Sbjct: 2639 DKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQ 2698
Query: 2443 PEPLSSSTSVLVTVTDVNDNPPRFQHHP----------YVTHIPSPTLPGSFVFAVTVTD 2492
P P + + V + D++DN P F P H P TL G+ AV D
Sbjct: 2699 PVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAV---D 2755
Query: 2493 ADIGPNSELHYSLSGRNSEK-FHIDPLRGAIMAAGPLNGASEVTFSVHVK 2541
AD GPN+ ++Y ++ N EK FH+ P G ++ L+ E FS VK
Sbjct: 2756 ADEGPNAIVYYFIAAGNEEKNFHLQP-DGCLLVLRDLDREREAIFSFIVK 2804
Score = 969 bits (2505), Expect = 0.0
Identities = 899/2894 (31%), Positives = 1334/2894 (46%), Gaps = 212/2894 (7%)
Query: 902 VVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGS 961
+ E+ G S+ Q A D D + +V + FA+ G + L PLD S
Sbjct: 42 ISEDTPVGSSVTQLLAQDMDN--DPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKS 99
Query: 962 -YQIEILASD-MGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQ 1019
+ +E SD GV + + V DVNDN+P F Y V + E+ PV + F V
Sbjct: 100 EFTVEFSVSDHQGVITRK----VNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVN 155
Query: 1020 ASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVASDR-AVE 1078
A+D D GA G + Y+ + A G + + ELD E Y L V A+D+
Sbjct: 156 ATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQDKTR 214
Query: 1079 PLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYS 1138
PLS N+ +I+ DV D P+F + Y+ E G+ V ++A+D+D G + Y+
Sbjct: 215 PLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYT 274
Query: 1139 FEMVQPD--FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIAT---DQGIPQPLKDQ 1193
+ F L ISG +T DRE+ + G F TV T D P
Sbjct: 275 IVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHG---FILTVKGTELNDDRTPSDATVT 331
Query: 1194 ATVHVYMKDINDNAPKFLKDFYQATISESAA---NLTQVLRVSASDVDEGNNGLIHYSII 1250
T ++ + DINDNAP+F Y I+E A L ++V D + G N + ++
Sbjct: 332 TTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLV 391
Query: 1251 KGNEERQFAIDSTSGQ------VTLIGKLDYEATPAYSLVIQAVDSGTIPLN-STCTLNI 1303
GN F I TS Q + + LDYE Y + A +S +P + + I
Sbjct: 392 -GNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANES--VPDHVGYAKVKI 448
Query: 1304 DILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTF 1363
+++ENDN P F + + + EN+ +G V +V ATD+D+G ++ Y + ++ F
Sbjct: 449 TLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFS--DDPDRF 506
Query: 1364 SISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPG 1423
S+ +TG I L +LD+E + L I A+D G +T V I+V D NDN P+F
Sbjct: 507 SLDKDTGLIMLIARLDYELIQRFTLTIIARDGGG--EETTGRVRINVLDVNDNVPTFQKD 564
Query: 1424 DIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTID--EVKGTIYTN 1481
++ EN P T ++ + A D D+ N Q++Y+I+ G++F I E G I +
Sbjct: 565 AYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVS 624
Query: 1482 AEIDREFAN--LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNA--LAA 1537
+D E + L LTV A D P VTI V D NDN P F S+ A ++
Sbjct: 625 RPLDYEQISNGLIYLTVMAMDAGNPPLNSTVP---VTIEVFDENDNPPTF-SKPAYFVSV 680
Query: 1538 DPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDT-FIVDRYSGDLRVASALV-PSQL 1595
+ + G+ + + A D D E I + + T F ++ SG++ S L ++
Sbjct: 681 VENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKS 740
Query: 1596 IYNLIVSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYITILKEGEPIGTNVISI 1651
Y LIV A D G + T T+ + LD P + Y L E P ++V ++
Sbjct: 741 EYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTV 800
Query: 1652 EAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTA-AILDREQG----ACLYL 1706
A P E Y + + + +++ TG I+T A+LDRE A L
Sbjct: 801 VAVDPDLGENGTLVYSI------QPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMR 854
Query: 1707 VDVYAIEKSTAFP--RTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTA 1764
V ++ P T A V + L D+NDN P F V E I G I Q+ A
Sbjct: 855 KIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVA 914
Query: 1765 MDADEGANALVTYTIISGADD-SFRIDPESGDLIATRRLDRERRSKYSLLVRADDG---L 1820
+D DEG N LV+Y + G F I+ SG ++ T LDRER ++Y L V A D
Sbjct: 915 IDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPT 974
Query: 1821 QSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIV 1880
+SS + I V DVND TP F VY+ + ED V + TD+D G+N E++Y +
Sbjct: 975 KSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFI 1034
Query: 1881 NEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGG----QFTTIRVYFNILD 1936
+ DG F + V LD E Y+L + A D G T V+ +LD
Sbjct: 1035 TGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLD 1094
Query: 1937 VNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD- 1995
VNDN PIF +SY S+ E++P G ++L TDAD+G ++ Y I G+ F +
Sbjct: 1095 VNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHV 1154
Query: 1996 KNGVL-KVLKALDRESQSFYNLVVQV--HDLPQIPASRFTSTAQVSIILLDVNDNPPTFL 2052
NG+L + + LDRE S + L+V+ HDL + S+ +V + + D+ND P F
Sbjct: 1155 SNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPM-----RSSVRVIVYVEDINDEAPVFT 1209
Query: 2053 SPKLTYIP--ENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTG 2110
+ + + E I T V QATD DSG + Y +L+ KF I G +
Sbjct: 1210 QQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVN 1269
Query: 2111 ELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTG 2170
LD E ++Y + V ATD+ P V + +L+ D F+ A Y+ I EN G
Sbjct: 1270 YLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALG 1329
Query: 2171 TDIIQVFAADGDEGTNGQVRYGIVNGNTNQE-FRIDSVTGAITVAKPLDREKTPTYHLTV 2229
T+I++V A D R+ + F+ID++TG ITV +DREK Y LTV
Sbjct: 1330 TEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTV 1389
Query: 2230 QATDRGSTPRTDTST-VSIVLLDINDFVPVFEL-SPYSVNVPENLGTLPRTILQVVARDD 2287
A D G P+ D++ V I +LD ND P F+ S +V++PE+ R + V A D
Sbjct: 1390 VADDGG--PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQR-VATVKAWDP 1446
Query: 2288 DRGSNSKLSYVLFGGNEDNAF----TLSASGELGVTQSLDRETKERFVLMITATDSGSPA 2343
D GSN ++ + L GN AF T + GE+ V + LDRE + ++L + A+D G+P
Sbjct: 1447 DAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPP 1506
Query: 2344 LTGTGTINVIVDDVNDNVPTFASK-AYFTTIPEDAPTGTDVLLVNASDADASKNAVIR-- 2400
+ V + D+NDN P S Y ++ E+ GT V+ V A+D D N+V+
Sbjct: 1507 RKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYY 1566
Query: 2401 IIGGNSQ--FTINPSTGQIITS-ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVT 2457
I GN F ++ +G+I T A DRE + Y LV D G+P LS++T V VT+
Sbjct: 1567 ITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPT-LSATTHVYVTIV 1625
Query: 2458 DVNDNPPRFQHHPYVTHIPS-PTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHI 2515
D NDN P FQ Y + P + + + D D GPN + Y++ +G F I
Sbjct: 1626 DENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRI 1685
Query: 2516 DPLRGAIMAAGPLN---GASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-------FP 2565
D G I AA L+ T V D T+ T VN D FP
Sbjct: 1686 DRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFP 1745
Query: 2566 KVRAKEQTFMFPENQPVSSLVTTITGSSLRGE--PMSYYIASGNLGNTFQIDQLTGQVSI 2623
R E F E QP + T + G + Y I G+ F I + G + +
Sbjct: 1746 --RDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRV 1803
Query: 2624 SQP--LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILEN 2681
+ LD E I Y + I ARD G PP SS + I VLD+NDN P+ P I EN
Sbjct: 1804 RKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISEN 1863
Query: 2682 LSPRKILT-VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYV 2740
+ V A D DSG N +L + I GN E +F IN TG + RPLDRE++ Y
Sbjct: 1864 SPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYK 1923
Query: 2741 LTIKSSDKGSPSQSTSVK-----VMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT-- 2792
LTI S K +P + ++I + DENDN P F++ + A V ENSP G +T
Sbjct: 1924 LTI--SVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVL 1981
Query: 2793 --RVTTSDEDIGINAISRYSIMDA-SLPFTINPSTGDIVISRP--LNRE--DTDRYRIRV 2845
+ D D I A+ Y ++ A S F IN STG + + ++RE + +
Sbjct: 1982 NGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLL 2041
Query: 2846 SAHDSGWTVST-DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSN 2904
A D G ST + I + D NDN P FS + + E G V QV ATD D G N
Sbjct: 2042 LAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLN 2101
Query: 2905 GQVFYFIKSQSE-YFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSL 2963
G++ Y I++ ++ F I+ TG +++ N T + V ++DRG L
Sbjct: 2102 GELVYRIEAGAQDRFLIHLVTG------VIRVGNAT-IDREEQESYRLTVVATDRGTVPL 2154
Query: 2964 ISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFI 3023
VTI I D ND+ P+FL V ++ + GT + +TAID LN ++EY I
Sbjct: 2155 SGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHD---LNPKLEYHI 2211
Query: 3024 SN-----------DNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGN--PPLS 3070
N F ++ +TG + V S + +L + +T++ D + P S
Sbjct: 2212 VGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERS 2271
Query: 3071 ---SQATVHITVTEENYHTPEFSQ---SHMSATIPESHSIGSIVRTVSARDRDAAMNGLI 3124
A + + V + N +TP+F ++ I E + G+ + V+A D D +NGL+
Sbjct: 2272 VSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLV 2331
Query: 3125 KYSISSGNEEGIFAI-NSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVN 3183
Y++ G + +SS G + + +DYE T+ A D G R V +
Sbjct: 2332 TYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLE 2391
Query: 3184 VIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVI 3243
++D+NDN+P+F Y V E+ P GT ++ + ATDADSG A+I Y++ +S F I
Sbjct: 2392 IVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESK-FAI 2450
Query: 3244 DPNTGVITTQGFLDFETKQSYHLTVKAFNVPDE----ERCSFATVNIQLKGTNEYVPRFV 3299
+P TG I LD E K Y LT A + P + R + V IQ+ N+ P+F
Sbjct: 2451 NPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFS 2510
Query: 3300 SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSG 3359
+ + E P GT V + A+D+D G +GE+ Y + G + F ++ +G +
Sbjct: 2511 KPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPG-VEAFHVDMDSGLVTTQR 2569
Query: 3360 ILDREKEERVSLKVLAKNFGS--IRGADIDEVTVNVTVLDANDP-PIFTL--NIYSVQIS 3414
L + E+ SL V+A + G + G + + V V+D ND P+F N + I
Sbjct: 2570 PL--QSYEKFSLTVVATDGGEPPLWGTTM----LLVEVIDVNDNRPVFVRPPNGTILHIR 2623
Query: 3415 EGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSI-NPQTGQITVTAELDRET 3472
E +P+ ++V V A D D + R+S+ +GN + F I +P +G I LDRE+
Sbjct: 2624 EEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRES 2683
Query: 3473 LPIYNLSVLAVDSGTPSATGSAS-LLVTLEDINDNGPMLT-VSEGE-------VMENKRP 3523
+Y+L ++A D G P + L V LEDI+DN P+ +G V E+
Sbjct: 2684 QAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPR 2743
Query: 3524 GTLVMTLQ-STDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQ--IADF 3580
GTLV + + D D PN YY ++ G F L G L R++DRE+ I F
Sbjct: 2744 GTLVGNVTGAVDADEGPNA--IVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSF 2801
Query: 3581 YLSVVTKDSGVPQMSSTGT-----------VHITVIDQNDNPSQSRTVEIFVNYYGNLFP 3629
+ + S P + T V + + D ND P + E +
Sbjct: 2802 IVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKV 2861
Query: 3630 GGILGSVKPQDPDV 3643
G L V D D+
Sbjct: 2862 GSELIQVLALDADI 2875
Score = 927 bits (2397), Expect = 0.0
Identities = 780/2504 (31%), Positives = 1211/2504 (48%), Gaps = 185/2504 (7%)
Query: 1324 VLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQ 1383
+ E+ +G V+ + A D D N L + ++G F++ P+TG ++L + LD ET+
Sbjct: 42 ISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK 98
Query: 1384 SLYKLNITAKD-QGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISV 1442
S + + + D QG T V I V D NDN P+F I EN P+GT + V
Sbjct: 99 SEFTVEFSVSDHQG----VITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 1443 TAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQ- 1501
A DPD G + Y+ P F ID +G + E+D E ++LTV A DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQD 211
Query: 1502 -AVPIETRRYALKNVTILVTDLNDNVPMFI----SQNALAADPSAVIGSVLTTIMAADPD 1556
P+ T L N+ I++TD+ D P+FI S N P G+ + I A D D
Sbjct: 212 KTRPLST----LANLAIIITDVQDMDPIFINLPYSTNIYEHSPP---GTTVRIITAIDQD 264
Query: 1557 EGANGEIEYEIINGDTDT-FIVDRYSGDLRVASALVPSQLIYN----LIVSATDLGPERR 1611
+G I Y I++G+T++ F +D SG L + L +Y+ L V T+L +R
Sbjct: 265 KGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRT 324
Query: 1612 KS----TTELTIILQGLD--GPVFTQPKYITILKEGEPIGTN----VISIEAASPRGSEA 1661
S TT I++ ++ P F +Y + E +G + ++ G +
Sbjct: 325 PSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNS 384
Query: 1662 PVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRT 1721
E Y+V + G+ I+ A LD E Y D++A E
Sbjct: 385 MFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET-VDRYDFDLFANESVP--DHV 441
Query: 1722 QRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIIS 1781
A+V+ITL + NDN P+F + ++++ EN+ G+ ++ + A D D G V+Y S
Sbjct: 442 GYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSY-FFS 500
Query: 1782 GADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA-DDGLQSSDMRINITVSDVNDHTPK 1840
D F +D ++G ++ RLD E +++L + A D G + + R+ I V DVND+ P
Sbjct: 501 DDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT 560
Query: 1841 FSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFF---LNPITGV 1897
F + Y + E+ + + + ATD+DS N +ITY + G +F L GV
Sbjct: 561 FQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGV 620
Query: 1898 FNLTRLLDYEV--QQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSL 1953
+++R LDYE LTV A D G +T+ V + D NDNPP FS +Y S+
Sbjct: 621 ISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSV 680
Query: 1954 MENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLKALDRESQS 2012
+EN+ G+TVL N TD D I S + QF ++ ++G + LDRE++S
Sbjct: 681 VENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKS 740
Query: 2013 FYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFL-SPKLTYIPENTPIDTVVFK 2071
Y L+V+ D + ++ T A V+I LLD+NDN PT+ +P + E TP D+ V
Sbjct: 741 EYILIVRAVD-GGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTT 799
Query: 2072 AQATDPDSGPNSYIEYTLLNPLGNKF-SIGTIDGEVRLT-GELDREEVSNYT------LT 2123
A DPD G N + Y++ P NKF S+ + G++R T LDRE + +
Sbjct: 800 VVAVDPDLGENGTLVYSIQPP--NKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIV 857
Query: 2124 VVATDKGQPSL--SSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADG 2181
V TD G+P L +SS V V +LD+NDN+P F + E+ E G I QV A D
Sbjct: 858 VSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDL 917
Query: 2182 DEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTD 2241
DEG NG V Y + G +F I+S +G + LDRE+ Y L V A+D G+ ++
Sbjct: 918 DEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSS 977
Query: 2242 TSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT--ILQVVARDDDRGSNSKLSYVL 2299
TST++I +LD+ND P F + Y+V+V E++ PR ++ + D+D G N++LSY +
Sbjct: 978 TSTLTIHVLDVNDETPTFFPAVYNVSVSEDV---PREFRVVWLNCTDNDVGLNAELSYFI 1034
Query: 2300 FGGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITATDSGSPAL--TGTGTINVIVDD 2356
GGN D F++ + LDRET ++L++ A D+G TGT T+ V V D
Sbjct: 1035 TGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLD 1094
Query: 2357 VNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI--RIIGGN--SQFTINP 2412
VNDN P F +Y ++PED P G +L + A+DAD + + RI+ GN + F I+
Sbjct: 1095 VNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHV 1154
Query: 2413 STGQIITSAL-LDRETKDNYTLVVVC--SDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHH 2469
S G ++ LDRE ++ L+V D G P+ SS V+V V D+ND P F
Sbjct: 1155 SNGLLMRGPRPLDRERNSSHVLIVEAYNHDLG---PMRSSVRVIVYVEDINDEAPVFTQQ 1211
Query: 2470 PYVTHIPSPTLP-GSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPL 2528
Y T G+ V V TD D G ++Y + KF ID G I+ L
Sbjct: 1212 QYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYL 1271
Query: 2529 NGASEVTFSVHVKDGGSFPKTDS--TTVTVRFVNKADFPKVRAKEQTF--MFPENQPVSS 2584
+ ++ ++ ++V P + +V + +N+ D V+ ++ EN + +
Sbjct: 1272 DYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELD-EAVQFSNASYEAAILENLALGT 1330
Query: 2585 LVTTITGSSLRGEPMSYY----IASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIE 2640
+ + S+ Y S F+ID +TG +++ +D EK Y + +
Sbjct: 1331 EIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVV 1390
Query: 2641 ARDGGFPPFSSYEKLDITVLDVNDNAPIFK--EDPFISEILENLSPRKILTVSAMDKDSG 2698
A DGG P S K+ ITVLD NDN+P F D +S + +++ TV A D D+G
Sbjct: 1391 ADDGG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAG 1449
Query: 2699 PNGQLDYEIVNGNMENSFSI---NHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQST 2755
NGQ+ + + +GN+ +F I N + GE+ RPLDRE++ HY+L + +SD+G+P +
Sbjct: 1450 SNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKK 1509
Query: 2756 SVKVMINILDENDNAPRFSQIFSAHVPENSPLG--YTVTRVTTSDEDIGINAISRYSIMD 2813
+ + ILD NDN P F +V N +G V +V +D DIGIN++ Y I +
Sbjct: 1510 DHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITE 1569
Query: 2814 AS--LPFTINPSTGDIVIS-RPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDIND 2867
+ + F ++ +G+I P +RE Y + + D G + +T V + + D ND
Sbjct: 1570 GNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDEND 1629
Query: 2868 NAPRFSRTSYYLDCPELTE-IGSKVTQVFATDPDEGSNGQVFYFIKSQS--EYFRINATT 2924
NAP F + Y + E + + + + + A D DEG NG V Y I + + FRI+
Sbjct: 1630 NAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1689
Query: 2925 GEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRG---KPSLISETTVTINIVDSNDNAP 2981
G I + L Y+ ++ R++ IVT++D+ L S TTV +N+ D NDN P
Sbjct: 1690 GVITAAKELDYE-------ISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVP 1742
Query: 2982 QFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWI 3041
F + Y P + D+D G N +VEY I + + LG+F + G +
Sbjct: 1743 TFPRD-YEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVL 1801
Query: 3042 SVASSLISDLNQNFF--ITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
V + D F +T+ A+D+G PPLSS V I V + N + P M+ TI
Sbjct: 1802 RVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITIS 1861
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
E+ + S V V A D D+ N + ++I++GN E F IN++TGI+T+ + LD E +
Sbjct: 1862 ENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPE 1921
Query: 3160 HEMTISAID---GGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHL 3216
+++TIS D +AR Y + + + D NDN P+F Y V+EN+P+GT + L
Sbjct: 1922 YKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVL 1981
Query: 3217 N----ATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQG--FLDFETKQSYHLTVKA 3270
N A DAD AV+ Y + + S LF I+ +TGV+T + +D E L +
Sbjct: 1982 NGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLL 2041
Query: 3271 FNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTD 3330
S A + I + N+ P F + E P G V +V A+D D G +
Sbjct: 2042 LAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLN 2101
Query: 3331 GEVHYLIFGNSRKKGFQINKKTGQIYV-SGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
GE+ Y I ++ + F I+ TG I V + +DRE++E L V+A + G++ + V
Sbjct: 2102 GELVYRIEAGAQDR-FLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIV 2160
Query: 3390 TVNVTVLDANDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGS-- 3446
T+ + D ND P F I +V + E GT + ++A D D P + Y I
Sbjct: 2161 TILID--DINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNP---KLEYHIVGIV 2215
Query: 3447 ---------GNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGT-----PSATG 3492
N+ AF++N TG + V + ++RE + Y +++ +D+ + +
Sbjct: 2216 AKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVP 2275
Query: 3493 SASLLVTLEDINDNGPM-----LTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYY 3547
+A L V + D+NDN P +T ++E PGT ++ + + DPD N G TY
Sbjct: 2276 NAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLN-GLVTYT 2334
Query: 3548 LLSTGPATSYFSL--STAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVI 3605
LL P Y L S+AG + R +D E++ +V D+G P ++ V++ ++
Sbjct: 2335 LLDLVP-PGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIV 2393
Query: 3606 DQNDN------PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV--LDSFHCSLTSGVTS 3657
D NDN PS V + ++ G I+ +V D D SL G S
Sbjct: 2394 DINDNNPIFDQPSYQEAV------FEDVPVGTIILTVTATDADSGNFALIEYSLGDG-ES 2446
Query: 3658 LFSIPGGTCD---LNSQPRSTDGTFDLTVLSNDGVHSTVTSNIR 3698
F+I T D L+S R + LT L+ D V SN R
Sbjct: 2447 KFAINPTTGDIYVLSSLDREKKDHYILTALAKDN-PGDVASNRR 2489
Score = 865 bits (2236), Expect = 0.0
Identities = 778/2653 (29%), Positives = 1227/2653 (46%), Gaps = 214/2653 (8%)
Query: 1098 PLFNSTNYTFYF--EEEQRAGSFVGKVSAVDKD-----FGPNGEVRYSFEMVQPDFELHA 1150
P F + + Y E+ GS V ++ A D D FG +GE F V+PD
Sbjct: 29 PFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPD----- 83
Query: 1151 ISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKF 1210
+G + DRE+ + T FS ++ QG+ V++ + D+NDNAP F
Sbjct: 84 -TGVVWLRQPLDRET--KSEFTVEFS---VSDHQGVIT-----RKVNIQVGDVNDNAPTF 132
Query: 1211 LKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLI 1270
Y I E+ T + V+A+D D G G + YS ++ FAIDS G VT+I
Sbjct: 133 HNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF--FAIDSARGIVTVI 190
Query: 1271 GKLDYEATPAYSLVIQAVDSG-TIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMR 1329
+LDYE T AY L + A D T PL++ L I I D D P F ++ E+
Sbjct: 191 RELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSP 250
Query: 1330 IGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQS----- 1384
G V +TA D D G + Y+I N + F++ +G + L LD E
Sbjct: 251 PGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGF 310
Query: 1385 LYKLNITAKDQGRPPRSSTMSVVIHVR--DFNDNPPSFPPGDIFKSIVENIPIGTSV--- 1439
+ + T + R P +T++ ++ D NDN P F + +I E +G ++
Sbjct: 311 ILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLF 370
Query: 1440 ISVTAHDPDADINGQLSYTIIQQMPRGNHFTID--EVKGT----IYTNAEIDREFANLFE 1493
I V D + +N ++ +HF I V+G I +D E + ++
Sbjct: 371 IQVVDKDENLGLNSMFEVYLVGN--NSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYD 428
Query: 1494 LTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQ-NALAADPSAVIGSVLTTIMA 1552
+ AN+ +VP YA +T++ + NDN P+F ++ + +G+ + T++A
Sbjct: 429 FDLFANE-SVPDHVG-YAKVKITLI--NENDNRPIFSQPLYNISLYENVTVGTSVLTVLA 484
Query: 1553 ADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLI--YNLIVSATDLGPER 1610
D D G GE+ Y + D D F +D+ +G L + A + +LI + L + A D G E
Sbjct: 485 TDNDAGTFGEVSY-FFSDDPDRFSLDKDTG-LIMLIARLDYELIQRFTLTIIARDGGGEE 542
Query: 1611 RKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA---SPRGSEAPVEYYI 1667
+ ++ + P F + Y+ L+E EP T ++ + A SP ++ + Y I
Sbjct: 543 TTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQ--ITYSI 600
Query: 1668 VSVRCEEKTVGRLFTIGRHTG--IIQTAAILDREQ--GACLYLVDVYAIEKSTAFPRTQR 1723
VS G F I + G +I + LD EQ +YL V A++ P
Sbjct: 601 VSA----SAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLT-VMAMDAGNP-PLNST 654
Query: 1724 AEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDAD---EGANALVTYTII 1780
V I + D NDNPP F ++V ENI G+ ++ L A D D E + Y++
Sbjct: 655 VPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLE 714
Query: 1781 SGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMR-----INITVSDVN 1835
FRI+ SG++ T LDRE +S+Y L+VRA DG + + +NIT+ D+N
Sbjct: 715 GSTQ--FRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDIN 772
Query: 1836 DHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPIT 1895
D+ P + Y ++ E T P S V ++A D D G NG + Y + ++ + LN T
Sbjct: 773 DNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNK--FYSLNSTT 830
Query: 1896 GVFNLTR-LLD------YEVQQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIF 1944
G T +LD +E + + V D G ++ V+ N+LD+NDN P F
Sbjct: 831 GKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTF 890
Query: 1945 SLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKN-GVLKVL 2003
+ ++E +P G ++ D D+G+N ++Y + G F ++ + GV+
Sbjct: 891 QNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTT 950
Query: 2004 KALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPEN 2062
LDRE + Y L V D S ST+ ++I +LDVND PTF + E+
Sbjct: 951 TELDRERIAEYQLRVVASDAGTPTKS---STSTLTIHVLDVNDETPTFFPAVYNVSVSED 1007
Query: 2063 TPIDTVVFKAQATDPDSGPNSYIEYTLLNP-LGNKFSIGTIDGEVRLTGELDREEVSNYT 2121
P + V TD D G N+ + Y + + KFS+G D VR LDRE + Y
Sbjct: 1008 VPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYM 1067
Query: 2122 LTVVATDKGQPSL--SSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAA 2179
L + A D G + + V V VLD+NDN PIF Q+ Y+ + E+ G I+Q+ A
Sbjct: 1068 LILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKAT 1127
Query: 2180 DGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVA-KPLDREKTPTYHLTVQATDRGSTP 2238
D DEG G+V Y I++GN FRI G + +PLDRE+ ++ L V+A + P
Sbjct: 1128 DADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGP 1187
Query: 2239 RTDTSTVSIVLLDINDFVPVFELSPYS-VNVPENLGTLPRTILQVVARDDDRGSNSKLSY 2297
+ V + + DIND PVF YS + + E G + +++ V A D D G ++Y
Sbjct: 1188 MRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAG-IGTSVIVVQATDRDSGDGGLVNY 1246
Query: 2298 VLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDV 2357
+ G E ++G + LD ETK +++ ++ATD P G ++ + + +
Sbjct: 1247 RILSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNE 1306
Query: 2358 NDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQ-----FTINP 2412
D F++ +Y I E+ GT+++ V A D R S F I+
Sbjct: 1307 LDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDA 1366
Query: 2413 STGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQH-HPY 2471
TG I L+DRE D YTL VV D G + S+ V +TV D NDN PRF
Sbjct: 1367 ITGVITVQGLVDREKGDFYTLTVVADDGGPK--VDSTVKVYITVLDENDNSPRFDFTSDS 1424
Query: 2472 VTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLR---GAIMAAGP 2527
IP G V V D D G N ++ +SL SG + F I G + A P
Sbjct: 1425 AVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1484
Query: 2528 LNGAS--EVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSL 2585
L+ V D G+ P+ + V ++ D P V + N+ V
Sbjct: 1485 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGG 1544
Query: 2586 VTTITGSSLRGE-----PMSYYIASGNLGNTFQIDQLTGQVSISQ-PLDFEKIQKYVVWI 2639
+ + + +SYYI GN F++D+++G+++ P D E+ Y +
Sbjct: 1545 TAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVA 1604
Query: 2640 EARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP----RKILTVSAMDK 2695
D G P S+ + +T++D NDNAP+F++ + E+L + P ++T+ A+D
Sbjct: 1605 TVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHY--EVLLDEGPDTLNTSLITIQALDL 1662
Query: 2696 DSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSH--YVLTIKSSDKG---S 2750
D GPNG + Y IV GN+ N+F I+ G I + + LD E +SH Y L + ++D+ S
Sbjct: 1663 DEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDYE-ISHGRYTLIVTATDQCPILS 1721
Query: 2751 PSQSTSVKVMINILDENDNAPRFSQIFSA--HVPENSPLGYTVTRVTTSDEDIGINAISR 2808
+++ V++N+ D NDN P F + + V E P G V D D G N
Sbjct: 1722 HRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQP-GPRVWTFLAHDRDSGPNGQVE 1780
Query: 2809 YSIMDASL--PFTINPSTGDIVISRP--LNREDTDRYRIRVSAHDSGWTVSTD---VTIF 2861
YSIMD F I+P G + + + L+RE Y + + A D G + V I
Sbjct: 1781 YSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIR 1840
Query: 2862 VTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKS--QSEYFR 2919
V DINDN P + E + + S V V A+D D G N ++ + I + + F
Sbjct: 1841 VLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFF 1900
Query: 2920 INATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DS 2976
INATTG + + L + + + ++ D + I+ + ++ D
Sbjct: 1901 INATTGIVTVNRPLDRERIP--------EYKLTISVKDNPENPRIARRDYDLLLIFLSDE 1952
Query: 2977 NDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHL-----GK 3031
NDN P F KS Y V +N GT L T ++ L+++ + + L G
Sbjct: 1953 NDNHPLFTKSTYQAEVMENSPAGTPL---TVLNGPILALDADQDIYAVVTYQLLGAQSGL 2009
Query: 3032 FKLDNDTGWISVASSLISDLNQN----FFITVTAKDKGNPPLSSQATVHITVTEENYHTP 3087
F +++ TG ++V S +I D + + A+D G L+S A + IT+ ++N + P
Sbjct: 2010 FDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGL--LNSTAHLLITILDDNDNRP 2067
Query: 3088 EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILT 3147
FS + ++ + E+ G V V+A D D+ +NG + Y I +G ++ F I+ TG++
Sbjct: 2068 TFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDR-FLIHLVTGVIR 2126
Query: 3148 LAKA-LDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLEN 3206
+ A +D E + + +T+ A D G V +G VT+ + D+ND+ P FL+ +VLE+
Sbjct: 2127 VGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLES 2186
Query: 3207 APSGTTVIHLNATDADSGTNAVIAYTVQS------------SDSDLFVIDPNTGVITTQG 3254
A GT + ++ A D D N + Y + + D F ++ NTG + +
Sbjct: 2187 AEPGTVIANITAIDHD--LNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKS 2244
Query: 3255 FLDFETKQSYHLTVKAF-NVPDEERCSFATVNIQLK----GTNEYVPRF--VSKLYYFE- 3306
++ E +Y +T+ N D S + N +L N+ P+F YY E
Sbjct: 2245 PMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMER 2304
Query: 3307 ISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI-NKKTGQIYVSGILDREK 3365
I E A GT + V A D D G +G V Y + Q+ + G++ + +D E+
Sbjct: 2305 ILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEE 2364
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVPIGTHVT 3424
++ V A + GS A E+ V + ++D ND PIF Y + E VP+GT +
Sbjct: 2365 VHWLNFTVRASDNGSPPRAA--EIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIIL 2422
Query: 3425 FVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVD 3484
V+A D+DS +++ Y +G G F+INP TG I V + LDRE Y L+ LA D
Sbjct: 2423 TVTATDADS-GNFALIEYSLGDGESK--FAINPTTGDIYVLSSLDREKKDHYILTALAKD 2479
Query: 3485 SGTPSATG----SASLLVTLEDINDNGPMLTVSE--GEVMENKRPGTLVMTLQSTDPDLP 3538
+ A+ S +++ + D+ND P + + V EN+ GT V+T+ +TD D
Sbjct: 2480 NPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEG 2539
Query: 3539 PNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSST 3597
PN G TY L GP F + +G+++T R + + F L+VV D G P + T
Sbjct: 2540 PN-GELTYSL--EGPGVEAFHVDMDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGT 2594
Query: 3598 GTVHITVIDQNDN 3610
+ + VID NDN
Sbjct: 2595 TMLLVEVIDVNDN 2607
Score = 593 bits (1528), Expect = e-168
Identities = 520/1719 (30%), Positives = 807/1719 (46%), Gaps = 151/1719 (8%)
Query: 74 LSESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPT---EVRVLVRDLND 130
LS + F I+ STG + T + +D E+ S ++N+ AP + V + + + D
Sbjct: 1249 LSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELD 1308
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
A F + S E+ + G +++ A D N + +R F++D
Sbjct: 1309 EAVQFSNASYEAAILENLALGTEIVRVQAYSID-NLNQITYRFNAYTSTQAKALFKIDAI 1367
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVF 250
+ +G +DRE Y L V V D G PK ++V +TV D NDN P F
Sbjct: 1368 TGV--------ITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRF 1418
Query: 251 G-SSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPET-----GL 304
+S +PED VG V V A D D G+N + + L + T G
Sbjct: 1419 DFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGE 1478
Query: 305 ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRY 364
+ V PLD E Y L V A DRG P + +LD+NDN PV++ +
Sbjct: 1479 VFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPF----GYN 1534
Query: 365 ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVAS 424
SV+EN GT V + TD D N +S I GN+ F + ++ + A
Sbjct: 1535 VSVNENVGGGTAVVQVRATDRDI-GINSVLSYYITEGNKDMAFRMD--RISGEIATRPAP 1591
Query: 425 ALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNL 484
DRER Y+L +V D G P S+ + + + D ND+ P+F Q Y V L
Sbjct: 1592 P-DRERQSFYHLVATVEDE-GTP------TLSATTHVYVTIVDENDNAPMFQQPHYEV-L 1642
Query: 485 SEEAPPGSYVS--GISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDR 542
+E P S I A D D G N + Y+IV+GN + F I H G++T LD
Sbjct: 1643 LDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKE--LDY 1700
Query: 543 ELA-SQIVLNISARDQGV---HPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPT 598
E++ + L ++A DQ H S ++V + D+ND P F + V E P
Sbjct: 1701 EISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQP- 1759
Query: 599 GTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSG--RLSTISSLDREEQAFYS 656
G + A D D G NG V +S+ + + F + PV G R+ LDRE AFY+
Sbjct: 1760 GPRVWTFLAHDRDSGPNGQVEYSIMDGDP-LGEFVISPVEGVLRVRKDVELDRETIAFYN 1818
Query: 657 LLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDP 716
L + A D G PP SS + + +LDINDN PV + I EN P S++ V A+D
Sbjct: 1819 LTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDA 1878
Query: 717 DLGTNGTVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPN 775
D G N + ++I+AG+R R F +NA +G+++ LDRE Y+L I D N ++P
Sbjct: 1879 DSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKD--NPENPR 1936
Query: 776 QA-----IVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNIS-YL 829
A ++ I + D DN P+F++ Y V EN G + ++ + L+++ Y
Sbjct: 1937 IARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYA 1996
Query: 830 ITT----GDQKGMFAINQVTGQLTTAN--VIDREEQS--FYQLKVVASG-GTVTGDTMVN 880
+ T G Q G+F IN TG +T + +IDRE S +L ++A G + +
Sbjct: 1997 VVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLL 2056
Query: 881 ITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLF 940
IT+ D NDN P F A +V+++EN G S+ Q A D D G+NG ++Y ++ ++ F
Sbjct: 2057 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRF 2116
Query: 941 AINEKNGTISLLGPLDV---HAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFD 997
I+ G I + G + SY++ ++A+D G LS + I+T+ + D+ND+ P F
Sbjct: 2117 LIHLVTGVIRV-GNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFL 2175
Query: 998 QLSYEVTLSESEPVNSRFFKVQASDKDSGANGE--IAYTIAEGNTG-------DAFGI-F 1047
V++ ES + + A D D E I +A+ +T DAF +
Sbjct: 2176 NPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNI 2235
Query: 1048 PDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNV-----TVILEDVNDNRPLFNS 1102
G + +KS ++REL Y + + D A + +V+V TV + DVNDN P F
Sbjct: 2236 NTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKP 2295
Query: 1103 TNYTFYFE---EEQRAGSFVGKVSAVDKDFGPNGEVRYSF-EMVQPDFEL--HAISGEIT 1156
T+Y E E G+ + V+AVD D G NG V Y+ ++V P + + +G++
Sbjct: 2296 FGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVI 2355
Query: 1157 NTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQ 1216
D E + +FTV A+D G P P + V++ + DINDN P F + YQ
Sbjct: 2356 ANRTVDYEEVHW------LNFTVRASDNGSP-PRAAEIPVYLEIVDINDNNPIFDQPSYQ 2408
Query: 1217 ATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYE 1276
+ E T +L V+A+D D GN LI YS+ G+ E +FAI+ T+G + ++ LD E
Sbjct: 2409 EAVFEDVPVGTIILTVTATDADSGNFALIEYSL--GDGESKFAINPTTGDIYVLSSLDRE 2466
Query: 1277 ATPAYSLVIQAVDS-GTIPLN---STCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGE 1332
Y L A D+ G + N ++ + I +LD ND P F K V EN G
Sbjct: 2467 KKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGT 2526
Query: 1333 LVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITA 1392
V ++ ATD D G N +L YS+ G F + ++G + + L ++ + L + A
Sbjct: 2527 SVITMMATDQDEGPNGELTYSLEGPGVEA-FHVDMDSGLVTTQRPL--QSYEKFSLTVVA 2583
Query: 1393 KDQGRPPRSSTMSVVIHVRDFNDNPPSF--PPGDIFKSIVENIPIGTSVISVTAHDPDAD 1450
D G PP T +++ V D NDN P F PP I E IP+ ++V V A D D
Sbjct: 2584 TDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEG 2643
Query: 1451 INGQLSYTIIQQMPRGNH----FTIDEVKGTIYTNAEIDREFANLFELTVKAND--QAVP 1504
+NG + Y+ ++ GN F ID + G I T +DRE ++ L + A+D Q VP
Sbjct: 2644 LNGAVRYSFLKTA--GNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVP 2701
Query: 1505 IETRRYALKNVTILVTDLNDNVPMFI-------SQNALAADPSAVIGSVLTTIMAA-DPD 1556
ET ++ + + + D++DN P+F+ L + G+++ + A D D
Sbjct: 2702 YET----MQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2757
Query: 1557 EGANGEIEYEIINGDTDTFIVDRYSGDLRVASALVPS-QLIYNLIVSATD---LGPERRK 1612
EG N + Y I G+ + + G L V L + I++ IV A+ P R
Sbjct: 2758 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2817
Query: 1613 STT----------ELTIILQGLDG--PVFTQPKYITILKEGEPIGTNVISIEAASPR-GS 1659
S T E+ ++L+ ++ P FT+ +Y + +G+ +I + A G+
Sbjct: 2818 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGN 2877
Query: 1660 EAPVEYYIVSVRC------EEKTVGRLFTIGRHTGIIQT 1692
+ V Y I+++ + + VG++FT+G GI++T
Sbjct: 2878 NSLVFYSILAIHYFRALANDSEDVGQVFTMGSMDGILRT 2916
Score = 391 bits (1005), Expect = e-108
Identities = 333/1096 (30%), Positives = 521/1096 (47%), Gaps = 66/1096 (6%)
Query: 2559 VNKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLT 2618
VN+ F + + E+ PV S VT + + +P+ + ++ F ++ T
Sbjct: 25 VNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDT 84
Query: 2619 GQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEI 2678
G V + QPLD E ++ V D K++I V DVNDNAP F P+ I
Sbjct: 85 GVVWLRQPLDRETKSEFTVEFSVSD---HQGVITRKVNIQVGDVNDNAPTFHNQPYSVRI 141
Query: 2679 LENLS-PRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVS 2737
EN I V+A D D G G + Y + F+I+ A G + +R LD E
Sbjct: 142 PENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPS--QFFAIDSARGIVTVIRELDYETTQ 199
Query: 2738 HYVLTIKSSDKGSPSQ-STSVKVMINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVT 2795
Y LT+ ++D+ ST + I I D D P F + +S ++ E+SP G TV +T
Sbjct: 200 AYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIIT 259
Query: 2796 TSDEDIGINAISRYSIMDASLP--FTINPSTGDIVISRPLNRED---TDRYRIRVSAHD- 2849
D+D G Y+I+ + F ++ +G + ++ L+RE+ + + + V +
Sbjct: 260 AIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL 319
Query: 2850 ------SGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKV---TQVFATDPD 2900
S TV+T I V DINDNAP F+ + Y + EL ++G + QV D +
Sbjct: 320 NDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEN 379
Query: 2901 EGSNGQV-FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRG 2959
G N Y + + S +F I+ T+ + K ++ + ++R+ F + +++
Sbjct: 380 LGLNSMFEVYLVGNNSHHFIISPTS--VQGKADIRIRVAIPLDYETVDRYDFDLFANE-S 436
Query: 2960 KPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEV 3019
P + V I +++ NDN P F + Y + +NV VGT ++ V A D+ D G EV
Sbjct: 437 VPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDN-DAGTFGEV 495
Query: 3020 EYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITV 3079
YF S+D +F LD DTG I + + L +L Q F +T+ A+D G + + V I V
Sbjct: 496 SYFFSDDP--DRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGR--VRINV 551
Query: 3080 TEENYHTPEFSQ-SHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIF- 3137
+ N + P F + +++ A S+ +VR + A D D+ N I YSI S + G +
Sbjct: 552 LDVNDNVPTFQKDAYVGALRENEPSVTQLVR-LRATDEDSPPNNQITYSIVSASAFGSYF 610
Query: 3138 --AINSSTGILTLAKALDYELCQKH--EMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV 3193
++ G++++++ LDYE +T+ A+D G VT+ V D NDN P
Sbjct: 611 DISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 670
Query: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADS----GTNAVIAYTVQSSDSDLFVIDPNTGV 3249
F YF +V+EN +G TV+ LNATD D G ++I Y+++ S F I+ +G
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESII-YSLEGSTQ--FRINARSGE 727
Query: 3250 ITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
ITT LD ETK Y L V+A + V ++ ATVNI L N+ P + YY +
Sbjct: 728 ITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINL 787
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVS-GILDREKE 3366
E P + V V A D DLG +G + Y I K + +N TG+I + +LDRE
Sbjct: 788 VEMTPPDSDVTTVVAVDPDLGENGTLVYSI--QPPNKFYSLNSTTGKIRTTHAMLDRENP 845
Query: 3367 ERVSLKVLAKNFGSIRGAD------IDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPI 3419
+ +++ K S+ TV V +LD ND P F + ++ EG+P
Sbjct: 846 DPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPA 905
Query: 3420 GTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
G + V A D D + SY + G F IN +G + T ELDRE + Y L
Sbjct: 906 GVSIYQVVAIDLDEGLN-GLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLR 964
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPML--TVSEGEVMENKRPGTLVMTLQSTDPDL 3537
V+A D+GTP+ + +++L + + D+ND P V V E+ V+ L TD D+
Sbjct: 965 VVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDV 1024
Query: 3538 PPNQGPFTYYLLSTGPATSYFSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGV--PQM 3594
N Y ++ G FS+ V+ T +DRE A + L + D+G +
Sbjct: 1025 GLNAE--LSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRH 1082
Query: 3595 SSTGTVHITVIDQNDN 3610
+ T TV +TV+D NDN
Sbjct: 1083 TGTATVFVTVLDVNDN 1098
Score = 239 bits (609), Expect = 7e-62
Identities = 226/745 (30%), Positives = 329/745 (44%), Gaps = 93/745 (12%)
Query: 45 PRQVFQVLEEQPPGTLVGTIQT-----RPGFTYRL-------------SESHALFAINSS 86
P Q VLE PGT++ I P Y + FA+N +
Sbjct: 2177 PIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNIN 2236
Query: 87 TGALYTTSTIDRESLPSDVINLVVLSSAPTYP--------TEVRVLVRDLNDNAPVFPDP 138
TG++ S ++RE + + + L V+ +A P ++ V V D+NDN P F
Sbjct: 2237 TGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPF 2296
Query: 139 SIVVTFK---EDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSG 195
I + E ++ G +I A D D G NG+ +Y ++ G +L+
Sbjct: 2297 GITYYMERILEGATPGTTLIAVAAVDPDKGLNGLV--TYTLLDLVPPGYVQLE------- 2347
Query: 196 EGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHY 255
+ + +++ +D E V D G P R + V + + DINDN P+F Y
Sbjct: 2348 DSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSY 2407
Query: 256 QAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEA 315
Q V ED VG+ +L V A DAD G A I Y L D + F ++P TG I V LD E
Sbjct: 2408 QEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREK 2467
Query: 316 RRQYSLTVQAMDRGVPSLTGRAE----ALIQLLDVNDNDPVVKFRYFPATSRYASVDENA 371
+ Y LT A D + R E +IQ+LDVND P F SV EN
Sbjct: 2468 KDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRP-----QFSKPQFSTSVYENE 2522
Query: 372 QVGTVVALLTVTDADSPAANGNISVQILG-GNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT V + TD D NG ++ + G G E H ++ S V + +
Sbjct: 2523 PAGTSVITMMATDQDE-GPNGELTYSLEGPGVEAFHVDMDSG--------LVTTQRPLQS 2573
Query: 431 IPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYR--VNLSEEA 488
++LTV +D G PP L++ V D+ND+ PVF + +++ EE
Sbjct: 2574 YEKFSLTVVATDG-GEPP------LWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEI 2626
Query: 489 PPGSYVSGISATDGDSGLNANLRYSIVSGNG---LGWFHISEHSGLVTTGSSGGLDRELA 545
P S V + ATD D GLN +RYS + G +F I SGL+ T LDRE
Sbjct: 2627 PLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQR--LDRESQ 2684
Query: 546 SQIVLNISARDQGVH-PKVSYAQLVVTLLDVNDEKPVF-----SQPEGYDVSVVENAPTG 599
+ L + A D G P + L V L D++D +P+F P+ ++V E++P G
Sbjct: 2685 AVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRG 2744
Query: 600 TEL-LMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLL 658
T + + A D D G N V + + A + ++F L P G L + LDRE +A +S +
Sbjct: 2745 TLVGNVTGAVDADEGPNAIVYYFI-AAGNEEKNFHLQP-DGCLLVLRDLDREREAIFSFI 2802
Query: 659 VLATDLGS--PPQS-----------SMARINVSLLDINDNSPVFYPVQYFAHIKENEPGG 705
V A+ S PP+ ++ + V L DIND P F +Y A + + G
Sbjct: 2803 VKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVG 2862
Query: 706 SYITTVSATDPDLGTNGTVKYSISA 730
S + V A D D+G N V YSI A
Sbjct: 2863 SELIQVLALDADIGNNSLVFYSILA 2887
Score = 130 bits (326), Expect = 4e-29
Identities = 157/545 (28%), Positives = 231/545 (42%), Gaps = 64/545 (11%)
Query: 3194 FLSDDYFPTVL---ENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD-SDLFVIDPNTGV 3249
F ++ +F T L E+ P G++V L A D D N + + V + S F ++P+TGV
Sbjct: 30 FFTNHFFDTYLLISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEEASRFFAVEPDTGV 86
Query: 3250 ITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISE 3309
+ + LD ETK + TV+ F+V D + VNIQ+ N+ P F ++ Y I E
Sbjct: 87 VWLRQPLDRETKSEF--TVE-FSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPE 143
Query: 3310 AAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERV 3369
P GT + V A+D DLG G V Y S+ F I+ G + V LD E +
Sbjct: 144 NTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQF--FAIDSARGIVTVIRELDYETTQAY 201
Query: 3370 SLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSA 3428
L V A + R + + + D D PIF YS I E P GT V ++A
Sbjct: 202 QLTVNATDQDKTRPLST-LANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITA 260
Query: 3429 FDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAV----- 3483
D D Y I SGN N F+++ +G +T+ LDRE P+Y+ +
Sbjct: 261 IDQDKGRPRG-IGYTIVSGNTNSIFALDYISGVLTLNGLLDREN-PLYSHGFILTVKGTE 318
Query: 3484 --DSGTPS-ATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKRPG-TLVMTLQSTDPDL 3537
D TPS AT + + + + DINDN P SE V E + G L + +Q D D
Sbjct: 319 LNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKD- 377
Query: 3538 PPNQG---PFTYYLLSTGPATSYFSLSTAGV-------LSTTREIDREQIADFYLSVVTK 3587
N G F YL+ G + +F +S V + +D E + + +
Sbjct: 378 -ENLGLNSMFEVYLV--GNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFAN 434
Query: 3588 DSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPG-------------GILG 3634
+S VP V IT+I++NDN ++ Y N+ G G G
Sbjct: 435 ES-VPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFG 493
Query: 3635 SVKPQDPDVLDSFHCSLTSGVTSLFSIPGGTCDLNSQPRSTDGTFDLTVLSNDGVHSTVT 3694
V D D F +G+ L + D R F LT+++ DG T
Sbjct: 494 EVSYFFSDDPDRFSLDKDTGLIMLIA----RLDYELIQR-----FTLTIIARDGGGEETT 544
Query: 3695 SNIRV 3699
+R+
Sbjct: 545 GRVRI 549
>gi|47059046 dachsous 2 isoform 1 [Homo sapiens]
Length = 2916
Score = 863 bits (2229), Expect = 0.0
Identities = 727/2530 (28%), Positives = 1142/2530 (45%), Gaps = 197/2530 (7%)
Query: 1017 KVQASDKDSGANGEIAYTIAEG----NTGDAFGIFP-DGQLYIKSELDRELQDR-YVLMV 1070
+V ASD DSG G I Y++ +G AF I P DGQ+ + ++DRE Y L+V
Sbjct: 78 EVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLV 137
Query: 1071 VASDRAVEP----------LSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVG 1120
A D + LSA V V LEDVNDN P+FN + Y +E + G+ +
Sbjct: 138 EAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEII 197
Query: 1121 KVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
V A D+D G G V Y I G +++ D + + + S
Sbjct: 198 NVLATDQDSGIYGTVAYEL-----------IPGNVSSLFTIDSTTGLYSPEVEILSAVNF 246
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQAT---ISESAANLTQVLRVSASDV 1237
+ D+ + L+ + + K + + K F + + L+V
Sbjct: 247 SADKEVMNSLEMFLPLLRHFKKVERDEEAAEKKFEASRGWFMRFKGRRHLHYLKVQDEAA 306
Query: 1238 DEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNS 1297
Y A G + L L + + SL++ A D G +
Sbjct: 307 SADGEAAARYVA-------NLAKILGEGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVI 359
Query: 1298 TCTLNIDILDENDNTPSF--PKSTLFV--DVLENMRIGELVSSVTATDSDSGDNADLYYS 1353
+ I I F PK T V DV E+ IG + + S+ ++Y
Sbjct: 360 NADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPIGTVKAREPLNSSEP-----IFYR 414
Query: 1354 ITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDF 1413
I+ + G FSI P G+I K LD ETQ + L + A+ G P S+ V I V D
Sbjct: 415 ISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQ-LGSAPACSSTEVNITVMDV 473
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDE 1473
NDN P+F I + P GT++ A D D+ NG + Y+I P F ID
Sbjct: 474 NDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQP--GVFAIDR 531
Query: 1474 VKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMF---- 1529
G ++ N + LT++A DQ V + AL +T+++ + ++ P +
Sbjct: 532 ALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQA---ALLVLTVVI-EKREHSPSWTFEH 587
Query: 1530 -ISQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIING-DTDTFIVDRYSGDLRVA 1587
+ Q ++ S + + T P A+ + Y + D+ F + Y+G + +
Sbjct: 588 LVYQVEVSESLSPMTQMLQTQAHPLGPQRAAS-PLRYSLEPSVDSAMFGIRPYTGWIYLR 646
Query: 1588 SAL-VPSQLIYNLIVSA--TDLGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPI 1644
S YN V A + G + STT + + D + + E P+
Sbjct: 647 RQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPV 706
Query: 1645 GTNVISIEAA--SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGA 1702
VI A G + Y+++S G+ F + +TG T ++ GA
Sbjct: 707 PQGVIGKITAIDMDSGKNGQLLYFLLSD-------GKFFKMNPNTGPAGTIYVITWADGA 759
Query: 1703 CLY----------------------------LVDVYAIEKST--------------AFPR 1720
+ L++ A+++ + PR
Sbjct: 760 AAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDREHRGHHEMTVLVTDRGSPPR 819
Query: 1721 TQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLT----AMDADEGANALVT 1776
V +++ DINDN P FP + + + +G + L A D DEG NA VT
Sbjct: 820 NATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVT 879
Query: 1777 YTIIS-GADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDG----LQSSDMRINITV 1831
Y++ S + D F+ID +G++ T L + R Y + V A D LQ + +NI V
Sbjct: 880 YSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRMSVIATDQGVPPLQGQAV-VNIQV 938
Query: 1832 SDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD-DSGVNGEITYIVNEDDEDGIFF 1890
++ S+ + IPE+ P +++ I ++D NG++ + + DD+DG F
Sbjct: 939 IPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFE 998
Query: 1891 LNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFT---TIRVYFNILDVNDNPPIFSLN 1947
++ TG L++ LDYE +Y+ V D + T+ + ++ D ND+ P F
Sbjct: 999 IDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLSIDVEDQNDHSPSFQDE 1058
Query: 1948 SYSTSLMENLPVGSTVLVFNVTDADDG--INSQLTYSIASGD-SLGQFTVDKN-GVLKVL 2003
S+ EN+P+G+ V VFN D DDG +NS++ Y I S + F + + G L +
Sbjct: 1059 LIVISVEENVPIGTLVYVFNAKD-DDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTV 1117
Query: 2004 KALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENT 2063
LDRES L V D R + I++LDVND+ PTF+S ++ E+
Sbjct: 1118 SRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFPNAHVKEDV 1177
Query: 2064 PIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK-FSIGTIDGEVRLTGELDREEVSNYTL 2122
+ ++V A DPD G N + Y++L+ N F + G + T LD E + + L
Sbjct: 1178 TVGSLVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHIL 1237
Query: 2123 TVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGD 2182
TV+A D G P+LSSS + V VLD+ND P+F Q LY+ + EN G + +V A D D
Sbjct: 1238 TVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRD 1297
Query: 2183 EGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDT 2242
G N ++++ I+ G + + F I+S TG + LDRE + L V D G + T
Sbjct: 1298 SGVNSKLQFEIMPGASFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSST 1357
Query: 2243 STVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGG 2302
+T+ + D ND P F +S Y + V EN P + V+A D D G+N + Y + G
Sbjct: 1358 TTILCTVEDENDHAPEFIVSSYDIEVLENQE--PEVVYTVLASDMDAGNNRAVEYHIIDG 1415
Query: 2303 NEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNV 2361
N D FT++ SGEL T++LDRE F L+I +D G P + + V V D ND+
Sbjct: 1416 NTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHS 1475
Query: 2362 PTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII---GGNSQFTINPSTGQII 2418
P+F + Y +++ EDA GT VL+++A D D N + FTI+P +G +
Sbjct: 1476 PSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLK 1535
Query: 2419 TSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSP 2478
TS LDRE + +T V D S++ + V VTDVNDN P + +P+ +
Sbjct: 1536 TSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPE 1595
Query: 2479 TLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIM-AAGPLNGASEVTFS 2537
+ V D D+GPN + +S + S F ID G I P + +
Sbjct: 1596 SPTNQTTVIVRADDLDLGPNGTVVFSFAETQS-MFSIDKYTGEIQFQQNPSSEYFPIWLQ 1654
Query: 2538 VHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTF--MFPENQPVSSLVTTITGSSLR 2595
+ V D G P +T + V + D K+ + + EN + + T+ +
Sbjct: 1655 LKVTDQG-IPARTTTGLLVIHMEGEDV-KISFSHHLYKGLVTENCEAGTSIVTVKAFAPD 1712
Query: 2596 G--EPMSYYIASGNLGNTFQIDQLTGQVSISQP--LDFEKIQKYVVWIEARDGGFPPFSS 2651
+ M Y I SGN + +GQ+++ +P LDFE + + + A G +
Sbjct: 1713 SIQDSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSGH---RA 1769
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMDKDSGPNGQLDYEIVNG 2710
Y K+ + + D NDN+P F++ + + + E+ L ++ V A D DSG NG ++Y I++G
Sbjct: 1770 YCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSG 1829
Query: 2711 NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNA 2770
N E +F I+ +G I + LD E S Y L ++++DKG P S + + + + D NDNA
Sbjct: 1830 NQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNA 1889
Query: 2771 PRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLP---FTINPSTGDI 2827
P F + + E+S G VT V+ D D+ N+ +S S P F I+ +TG +
Sbjct: 1890 PAFLPSEAVEITEDSLPGVIVTHVSVHDVDL--NSAFIFSFAKESNPGTKFAIDQNTGVV 1947
Query: 2828 VISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEI 2887
V+ + L+ E+ Y + + DS + + V D+NDN P FS+ Y + PE +
Sbjct: 1948 VLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPV 2007
Query: 2888 GSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNIN 2947
G V + ATD + SN + Y I S S+ F I+ G IF + + I+
Sbjct: 2008 GYSVLTLSATDLE--SNENISYRILSSSKEFSIDPKNGTIFTISPVLLLDT-------IS 2058
Query: 2948 RHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTA 3007
F+V +SD G P L + T V I I D N+ AP+F Y ++++ VG+ L+ +
Sbjct: 2059 TTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSN 2118
Query: 3008 IDDKDFGLNSEVEYFISNDNHLGKFKLDN----------DTGWISVASSLISDLNQNFFI 3057
ID N+ VEY I + N F ++ G++ + SL + + + +
Sbjct: 2119 IDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHEL 2178
Query: 3058 TVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRD 3117
+ A D G PPLSS A + I V + N + P FS + ES +GS + VSA DRD
Sbjct: 2179 VILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRD 2238
Query: 3118 AAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGY 3177
+ I Y+I SGNE+G F + +TG+L L K LDYE K +T+ A D +
Sbjct: 2239 TGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAE-KKHFSF 2297
Query: 3178 CSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV---- 3233
V V+V+D ND++P F+ + V EN P +T+ +NA D D+G + Y++
Sbjct: 2298 AVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVSPC 2357
Query: 3234 -----QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
S D DLF+IDP TG I + LD+E Y LTV+A + D V+I+
Sbjct: 2358 FLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGDATASLVVWVDIE- 2416
Query: 3289 KGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI 3348
G +E+ P F Y+F + E ++G V ASD D G DG + Y + + F +
Sbjct: 2417 -GIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL--GTSSPFFSV 2473
Query: 3349 NKKTGQIYVSGIL-----DREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPI 3403
NK G IY+ L KE+ + +K++A + S V VNV+ P
Sbjct: 2474 NKTNGNIYLIRALPLIKSQLNKEDTLEMKIIAHSPKSDSKFASCTVFVNVSFSSEGTPLA 2533
Query: 3404 FTLNIYSVQI 3413
+ +S+ +
Sbjct: 2534 VFASSFSISL 2543
Score = 743 bits (1917), Expect = 0.0
Identities = 708/2564 (27%), Positives = 1142/2564 (44%), Gaps = 245/2564 (9%)
Query: 43 AEPRQVFQVLEEQPPGTLVGTIQTRPGFTYRLSESHALFAINSSTGALYTTSTIDRESLP 102
A+P + +V L G I+ + E+ F I+ G + + IDRE P
Sbjct: 71 AKPVKETEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDP 130
Query: 103 SD--------------VINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDS 148
+ + +L ++ + VRV + D+NDN PVF + V + +++
Sbjct: 131 ATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDET 190
Query: 149 SSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGL 208
G ++I ATD D G G +Y +I GN + F +D T +
Sbjct: 191 QPGTEIINVLATDQDSGIYGT--VAYELIPGNVSSLFTIDSTTGLYSPEVEILSAVNFSA 248
Query: 209 DREVTPQYQLLVEV--------------EDKGEPKRRGYLQVNVTVQDINDNPPVFGSSH 254
D+EV ++ + + E K E R +++ G H
Sbjct: 249 DKEVMNSLEMFLPLLRHFKKVERDEEAAEKKFEASRGWFMRFK-------------GRRH 295
Query: 255 YQAGVPEDAVVGSSVLQVAAADADEGTN--ADIRYRLQDEGTPFQMDPETGLITVREPLD 312
+D + A+AD + A++ L + G+I + PL
Sbjct: 296 LHYLKVQD--------EAASADGEAAARYVANLAKILGE-----------GIIYLTLPLS 336
Query: 313 FEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQ 372
SL V A D G + A+ I + P R Y V E++
Sbjct: 337 HLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTT-LAPAEFERPKYTFLVYEDVPEDSP 395
Query: 373 VGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIP 432
+GTV A + S IS LGG H P L I+ LD E P
Sbjct: 396 IGTVKAREPLN--SSEPIFYRISSGDLGGKFSIH--------PRLGTIRTRKPLDHETQP 445
Query: 433 SYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGS 492
LTV G+ P S + I V D+ND+ P F + + +S+ PPG+
Sbjct: 446 VVVLTVQA--QLGSAPAC------SSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGT 497
Query: 493 YVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNI 552
+ A D DSG N +RYSI S G F I G++ S G + ++ L +
Sbjct: 498 ALYLARAEDRDSGRNGLIRYSIASPQP-GVFAIDRALGVLFLNGSLGAGEQ--RELTLTL 554
Query: 553 SARDQGVHPKVSYAQLVVTLLDVNDEKPVFS-QPEGYDVSVVENAPTGTELLMLRATD-G 610
A DQGVHP+ + L V +++ + P ++ + Y V V E+ T++L +A G
Sbjct: 555 RAEDQGVHPQAALLVLTV-VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLG 613
Query: 611 DLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQS 670
+R+SL E D F + P +G + D E Y+ V A P
Sbjct: 614 PQRAASPLRYSL-EPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFA---WIPEDG 669
Query: 671 SMARINVSLL----DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKY 726
+ ++ +++ D NDNSP F F ++E+ I ++A D D G NG + Y
Sbjct: 670 FLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLY 729
Query: 727 SISAGDRSRFQVNAQSGVIST--------------------------------------- 747
+ D F++N +G T
Sbjct: 730 FL-LSDGKFFKMNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGE 788
Query: 748 -----RMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQV----AY 798
+ALDRE + +++ ++ TD G+ V ++V D DN P F Q
Sbjct: 789 GELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKEL 848
Query: 799 SFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTTANVIDR 856
V E + V +V A D N+ ++Y +++ D F I+ G++ T ++
Sbjct: 849 HVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSY 908
Query: 857 EEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIF 913
+ + Y++ V+A+ V G +VNI V L+ Q I + + EN + +
Sbjct: 909 DYRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMS 968
Query: 914 QAKAVDP-DEGVNGMVLYSLKQNPKN-LFAINEKNGTISLLGPLDVHAGS-YQIEILASD 970
K+ D + NG + +S+ + K+ F I+ G + L LD S Y ++ +D
Sbjct: 969 LIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTD 1028
Query: 971 MGVP-QLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKD-SGAN 1028
LSS+V L++ V D ND+SP F +++ E+ P+ + + A D D S N
Sbjct: 1029 HSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLN 1088
Query: 1029 GEIAYTIAEGNTG-DAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLS---AT 1083
I Y I N G + F I P G L S LDRE +L V ASD+AV +
Sbjct: 1089 SRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRS 1148
Query: 1084 VNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQ 1143
+ +++ DVND+ P F S + +E+ GS V ++A D D G NG+V YS
Sbjct: 1149 LTAQIVILDVNDHNPTFISFP-NAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSGN 1207
Query: 1144 PD--FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMK 1201
+ F L SG +T T D E + TV+A D G P L T+ V +
Sbjct: 1208 ENMTFMLDESSGLLTTTCPLDYEMKTQH------ILTVLALDDGTP-ALSSSQTLTVTVL 1260
Query: 1202 DINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAID 1261
D+ND AP F + Y+A++ E+ V RV A D D G N + + I+ G F I+
Sbjct: 1261 DVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEIN 1320
Query: 1262 STSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLF 1321
S +G+V LD E ++L + D G L+ST T+ + DEND+ P F S+
Sbjct: 1321 SDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYD 1380
Query: 1322 VDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFE 1381
++VLEN E+V +V A+D D+G+N + Y I N F+I+ +G + + LD E
Sbjct: 1381 IEVLENQE-PEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSGELSTTRALDRE 1439
Query: 1382 TQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVIS 1441
S + L I D G PPRSS + + + V D ND+ PSFP S+ E+ +GT V+
Sbjct: 1440 QISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLV 1499
Query: 1442 VTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQ 1501
++A D D +NGQ Y + + FTID + GT+ T+ +DRE + + A D
Sbjct: 1500 LSAVDKDEGLNGQTEYFLTDE--ASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARD- 1556
Query: 1502 AVPIETRRYALKNVTILVTDLNDNVPMFISQNA--LAADPSAVIGSVLTTIMAADPDEGA 1559
I+ R + + VTD+NDN P+ + QN + P + + A D D G
Sbjct: 1557 -CSIQGSRSTTVIIKVYVTDVNDNDPV-LEQNPFDVFLSPESPTNQTTVIVRADDLDLGP 1614
Query: 1560 NGEIEYEIINGDTDTFIVDRYSGDLRVASALVPSQLIYNLIVSATDLGPERRKSTTELTI 1619
NG + + + F +D+Y+G+++ L + TD G R +T L I
Sbjct: 1615 NGTVVFSFAETQS-MFSIDKYTGEIQFQQNPSSEYFPIWLQLKVTDQGIPARTTTGLLVI 1673
Query: 1620 ILQGLDGPV-FTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVG 1678
++G D + F+ Y ++ E GT++++++A +P + ++Y I S E+ +
Sbjct: 1674 HMEGEDVKISFSHHLYKGLVTENCEAGTSIVTVKAFAPDSIQDSMKYSIFSGN-EDGVLS 1732
Query: 1679 RLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPP 1738
G+ T ++ LD E + L+ + A+ +V + +QD NDN P
Sbjct: 1733 LCSKSGQLT--VKEPKFLDFEVRNEVQLIVLAESSGHRAY-----CKVAVLIQDENDNSP 1785
Query: 1739 VFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLI 1797
F + +V E+ + ++Q+ A D D G N L+ Y+I+SG +++F+ID SG +
Sbjct: 1786 CFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVIT 1845
Query: 1798 ATRRLDRERRSKYSLLVRA-DDGLQ--SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDT 1854
LD E S YSL+V+A D G+ S+ I + V+D+ND+ P F P + +I ED+
Sbjct: 1846 TKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAF-LPSEAVEITEDS 1904
Query: 1855 IPGSLVAAILATDDDSGVNGEITYIVNEDDEDGI-FFLNPITGVFNLTRLLDYEVQQYYI 1913
+PG +V + D D +N + ++ G F ++ TGV L + LD+E Y
Sbjct: 1905 LPGVIVTHVSVHDVD--LNSAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYE 1962
Query: 1914 LTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADD 1973
L ++ D +T + +LDVNDNPP+FS + Y ++ E++PVG +VL + TD +
Sbjct: 1963 LLIQISD-SVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLES 2021
Query: 1974 GINSQLTYSIASGDSLGQFTVD-KNG-VLKVLKALDRESQSFYNLVVQVHDLPQIPASRF 2031
N ++Y I S S +F++D KNG + + L ++ S +V+ D P R
Sbjct: 2022 --NENISYRILS--SSKEFSIDPKNGTIFTISPVLLLDTISTTQFLVEASDGGN-PDLRA 2076
Query: 2032 TSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPD-SGPNSYIEYTL 2089
+ ++ I D+N+ P F + E+ + + + D D + N+Y+EY++
Sbjct: 2077 LTLVEIGI--EDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSI 2134
Query: 2090 LNPLG-NKFSIGT----------IDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSST 2138
++ N F + T G + L LDRE +++ L ++A+D G P LSS+
Sbjct: 2135 ISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSSTA 2194
Query: 2139 EVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNT 2198
+ + VLD+NDN P F+ Y + E+T G+ I V A D D G++ ++ Y I++GN
Sbjct: 2195 VISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEIIYNIISGNE 2254
Query: 2199 NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPV 2258
F ++ TG + + KPLD EK + LTVQA+D + V + +LD ND P
Sbjct: 2255 KGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD-AEKKHFSFAVVFVSVLDDNDHAPQ 2313
Query: 2259 FELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSY-------VLFGGNEDNAFTL- 2310
F S +S VPENL + TI + A D D G +L+Y + G + D+ L
Sbjct: 2314 FMFSSFSCIVPENL-PISSTICSINALDFDAGPYGELTYSIVSPCFLTHGMSYDHDLFLI 2372
Query: 2311 -SASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAY 2369
+G++ Q LD E ++ L + A D G T + + V ++ +++ P F Y
Sbjct: 2373 DPLTGDIHAKQILDYENGNKYCLTVQAKDKGD--ATASLVVWVDIEGIDEFEPIFTQDQY 2430
Query: 2370 FTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQ--FTINPSTGQI-------ITS 2420
F T+PE + V ASDADA + VI G S F++N + G I +
Sbjct: 2431 FFTLPEKNKDRQLIGRVEASDADAGIDGVILYSLGTSSPFFSVNKTNGNIYLIRALPLIK 2490
Query: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPP 2464
+ L++E D + ++ S +S T V V V+ ++ P
Sbjct: 2491 SQLNKE--DTLEMKIIAHSPKSDSKFASCT-VFVNVSFSSEGTP 2531
Score = 711 bits (1836), Expect = 0.0
Identities = 678/2531 (26%), Positives = 1127/2531 (44%), Gaps = 258/2531 (10%)
Query: 139 SIVVTFKEDSSSGRQVILDTATDSDIGSNG-VDHRSYRIIRGNEAGR-FRLDITLNPSGE 196
+IV +E+++ + TA+D+D G G +++ Y EA + FR+D +
Sbjct: 61 AIVFRSQEENAKPVKETEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRID-----PHD 115
Query: 197 GAFLHLVSKGGLDREVTPQ-YQLLVEVEDKGEPKRRGYLQ-----------VNVTVQDIN 244
G + +DRE P Y LLVE +D G+ +R +L V V ++D+N
Sbjct: 116 G---QICVSQDIDRERDPATYDLLVEAKD-GDEQRMTHLALVKGGLSAQAFVRVDLEDVN 171
Query: 245 DNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL--QDEGTPFQMDPET 302
DN PVF S Y + ++ G+ ++ V A D D G + Y L + + F +D T
Sbjct: 172 DNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTT 231
Query: 303 GL----ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYF 358
GL + + ++F A ++ + +++ +P L++ + D + F
Sbjct: 232 GLYSPEVEILSAVNFSADKE---VMNSLEMFLP--------LLRHFKKVERDEEAAEKKF 280
Query: 359 PATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLS 418
A+ + + + + L V D ++ +A+G + + + +K+
Sbjct: 281 EASRGWFMRFKGRRH---LHYLKVQD-EAASADGEAAAR---------YVANLAKILGEG 327
Query: 419 LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQ 478
+I + L + +L VS D G A + A + I + P F +
Sbjct: 328 IIYLTLPLSHLESTTLSLMVSAQDGGGLT--AVINA-----DVTIHIFQTTLAPAEFERP 380
Query: 479 VYRVNLSEEAPPGSYVSGISATDGDSGLNAN--LRYSIVSGNGLGWFHISEHSGLVTTGS 536
Y + E+ P S + + A + LN++ + Y I SG+ G F I G + T
Sbjct: 381 KYTFLVYEDVPEDSPIGTVKAREP---LNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRK 437
Query: 537 SGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENA 596
LD E +VL + A+ G P S ++ +T++DVND P F + ++ + +
Sbjct: 438 P--LDHETQPVVVLTVQAQ-LGSAPACSSTEVNITVMDVNDNHPAFLRTSD-EIRISQTT 493
Query: 597 PTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYS 656
P GT L + RA D D G NG +R+S+ A F +D G L SL EQ +
Sbjct: 494 PPGTALYLARAEDRDSGRNGLIRYSI--ASPQPGVFAIDRALGVLFLNGSLGAGEQRELT 551
Query: 657 LLVLATDLGSPPQSSMARINVSLLDINDNSP--VFYPVQYFAHIKEN-EPGGSYITTVSA 713
L + A D G PQ+++ + V +++ ++SP F + Y + E+ P + T +
Sbjct: 552 LTLRAEDQGVHPQAALLVLTV-VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAH 610
Query: 714 TDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVA--TDGGN 770
++YS+ D + F + +G I R D E Y ++ A + G
Sbjct: 611 PLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGF 670
Query: 771 LQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLI 830
LQ+ + ++ + V D DN P F V E+ +G ++A MD N L
Sbjct: 671 LQNVSTTVI-VRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLY 729
Query: 831 TTGDQKGMFAINQVTGQLTTANVI------------------------------------ 854
F +N TG T VI
Sbjct: 730 FLLSDGKFFKMNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEG 789
Query: 855 --------DREEQSFYQLKVVAS--GGTVTGDTM-VNITVKDLNDNSPHFLQAIES---- 899
DRE + +++ V+ + G TM V ++V D+NDN P F Q +
Sbjct: 790 ELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELH 849
Query: 900 VNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK-QNPKNLFAINEKNGTISLLGPLDV- 957
V V+E + A DPDEG N V YS+ ++ + F I+ NG I L
Sbjct: 850 VKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYD 909
Query: 958 HAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFK 1017
+ SY++ ++A+D GVP L ++ + V ++ + Q + + E+
Sbjct: 910 YRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSL 969
Query: 1018 VQASDK-DSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDR 1075
+++SD NG++ ++I + F I G L++ ELD E Y+ V+ +D
Sbjct: 970 IKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDH 1029
Query: 1076 AVE-PLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG-PNG 1133
+ LS+TV +++ +ED ND+ P F EE G+ V +A D D N
Sbjct: 1030 SKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNS 1089
Query: 1134 EVRYSFEMVQPD---FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
++Y E P F +H G + + DRES+ TV A+DQ +
Sbjct: 1090 RIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESI------PTVILTVTASDQAVNVTD 1143
Query: 1191 KD--QATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYS 1248
+ T + + D+ND+ P F+ F A + E + V ++A D DEG NG + YS
Sbjct: 1144 RRLRSLTAQIVILDVNDHNPTFIS-FPNAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYS 1202
Query: 1249 IIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDE 1308
I+ GNE F +D +SG +T LDYE + L + A+D GT L+S+ TL + +LD
Sbjct: 1203 ILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDV 1262
Query: 1309 NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN 1368
ND P F + V EN GE V+ V A D DSG N+ L + I + F I+ +
Sbjct: 1263 NDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINSD 1322
Query: 1369 TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKS 1428
TG + LD E Q ++ L + +D G P SST +++ V D ND+ P F
Sbjct: 1323 TGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIE 1382
Query: 1429 IVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH---FTIDEVKGTIYTNAEID 1485
++EN V +V A D DA N + Y II GN FTI+E+ G + T +D
Sbjct: 1383 VLEN-QEPEVVYTVLASDMDAGNNRAVEYHIID----GNTDECFTINEMSGELSTTRALD 1437
Query: 1486 REFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS---QNALAADPSAV 1542
RE + F L + +D P R ++ ++ + V D ND+ P F + Q+++ D A
Sbjct: 1438 REQISNFTLVILCSDLGDP---PRSSVIHLQVRVLDANDHSPSFPTLYYQSSVRED--AE 1492
Query: 1543 IGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASAL---VPSQLIYNL 1599
+G+V+ + A D DEG NG+ EY + + + F +D SG L+ ++ L SQ ++
Sbjct: 1493 VGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLKTSNTLDREARSQHTFSA 1552
Query: 1600 IVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGS 1659
+ A D + +STT + + Y+T + + +P+ SP
Sbjct: 1553 V--ARDCSIQGSRSTTVIIKV-------------YVTDVNDNDPVLEQNPFDVFLSP--- 1594
Query: 1660 EAPVEYYIVSVRCEEKTVG-------------RLFTIGRHTGIIQTAAILDREQGACLYL 1706
E+P V VR ++ +G +F+I ++TG IQ + + +
Sbjct: 1595 ESPTNQTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDKYTGEIQ----FQQNPSSEYFP 1650
Query: 1707 VDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMD 1766
+ + P + + + D F + V EN G+ I+ + A
Sbjct: 1651 IWLQLKVTDQGIPARTTTGLLVIHMEGEDVKISFSHHLYKGLVTENCEAGTSIVTVKAFA 1710
Query: 1767 ADEGANALVTYTIISGADDS-FRIDPESGDLIA--TRRLDRERRSKYSLLVRADDGLQSS 1823
D +++ Y+I SG +D + +SG L + LD E R++ L+V A+ +
Sbjct: 1711 PDSIQDSM-KYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSGHRA 1769
Query: 1824 DMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNED 1883
++ + + D ND++P F + +Y + E + + V + ATD DSG+NG I Y +
Sbjct: 1770 YCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSG 1829
Query: 1884 DEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG----GQFTTIRVYFNILDVND 1939
+++ F ++ ++GV +LDYE+ Y L V+A D G T I+V + D+ND
Sbjct: 1830 NQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKV--QVTDIND 1887
Query: 1940 NPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLG-QFTVDKN- 1997
N P F L S + + E+ G V+V +V+ D +NS +S A + G +F +D+N
Sbjct: 1888 NAPAF-LPSEAVEITEDSLPG--VIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQNT 1944
Query: 1998 GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSP-KL 2056
GV+ ++K LD E + Y L++Q+ D + +T A V + +LDVNDNPP F
Sbjct: 1945 GVVVLVKTLDFEEMTEYELLIQISD-----SVHYTEGALV-VRVLDVNDNPPVFSQDFYQ 1998
Query: 2057 TYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEV-RLTGELDRE 2115
+PE+ P+ V ATD +S N I Y +L+ +FSI +G + ++ L +
Sbjct: 1999 VTVPESIPVGYSVLTLSATDLESNEN--ISYRILSS-SKEFSIDPKNGTIFTISPVLLLD 2055
Query: 2116 EVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQ 2175
+S V A+D G P L + T V + + D+N+ P F Y + ++E+ L G+ ++
Sbjct: 2056 TISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVT 2115
Query: 2176 VFAADGD-EGTNGQVRYGIVNGNTNQEFRIDS----------VTGAITVAKPLDREKTPT 2224
D D N V Y I++GN+ F +++ G + + LDRE + +
Sbjct: 2116 FSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASAS 2175
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVA 2284
+ L + A+D G P + T+ +SI +LD+ND P F Y +V E+ L I V A
Sbjct: 2176 HELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKEST-PLGSHITVVSA 2234
Query: 2285 RDDDRGSNSKLSYVLFGGNEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPA 2343
D D GS++++ Y + GNE F L +G L + + LD E +F L + A+D+
Sbjct: 2235 NDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEKKH 2294
Query: 2344 LTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR--- 2400
+ ++DD ND+ P F ++ +PE+ P + + +NA D DA +
Sbjct: 2295 FSFAVVFVSVLDD-NDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSI 2353
Query: 2401 -----IIGGNSQ----FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTS 2451
+ G S F I+P TG I +LD E + Y L V D G ++S
Sbjct: 2354 VSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGD---ATASLV 2410
Query: 2452 VLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSE 2511
V V + +++ P F Y +P + V +DAD G + + YSL G +S
Sbjct: 2411 VWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL-GTSSP 2469
Query: 2512 KFHIDPLRGAI 2522
F ++ G I
Sbjct: 2470 FFSVNKTNGNI 2480
Score = 697 bits (1798), Expect = 0.0
Identities = 637/2317 (27%), Positives = 1034/2317 (44%), Gaps = 194/2317 (8%)
Query: 1425 IFKSIVENI-PIGTSVISVTAHDPDADINGQLSYTIIQ-----QMPRGNHFTIDEVKGTI 1478
+F+S EN P+ + VTA D D+ + G + Y++ + P+ F ID G I
Sbjct: 63 VFRSQEENAKPVKET--EVTASDADSGLYGFIEYSLYDGFLSYEAPQA--FRIDPHDGQI 118
Query: 1479 YTNAEIDREF-ANLFELTVKANDQAVPIETRRYALKN-------VTILVTDLNDNVPMFI 1530
+ +IDRE ++L V+A D T +K V + + D+NDN P+F
Sbjct: 119 CVSQDIDRERDPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFN 178
Query: 1531 -SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDT-FIVDR----YSGDL 1584
S + G+ + ++A D D G G + YE+I G+ + F +D YS ++
Sbjct: 179 PSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEV 238
Query: 1585 RVASAL-------VPSQLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKYITI 1637
+ SA+ V + L L + ER + E F +++
Sbjct: 239 EILSAVNFSADKEVMNSLEMFLPLLRHFKKVERDEEAAEKKFEASRGWFMRFKGRRHLHY 298
Query: 1638 LKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILD 1697
LK + EAAS G A Y+ ++ K +G GII L
Sbjct: 299 LK---------VQDEAASADGEAAA--RYVANLA---KILGE--------GIIYLTLPLS 336
Query: 1698 REQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGS 1757
+ L L+ + + A+V I + P F V E++ + S
Sbjct: 337 HLESTTLSLM--VSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDS 394
Query: 1758 KIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLLVRA 1816
I + A + + + Y I SG F I P G + + LD E + L V+A
Sbjct: 395 PIGTVKAREPLNSSEPIF-YRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQA 453
Query: 1817 DDGLQS--SDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNG 1874
G S +NITV DVND+ P F R I + T PG+ + A D DSG NG
Sbjct: 454 QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNG 513
Query: 1875 EITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQ-FTTIRVYFN 1933
I Y + + G+F ++ GV L L Q+ LT+RAED G + V
Sbjct: 514 LIRYSI-ASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTV 572
Query: 1934 ILDVNDNPPIFSLNS--YSTSLMENLPVGSTVLVFNVTD-ADDGINSQLTYSIASGDSLG 1990
+++ ++ P ++ Y + E+L + +L S L YS+
Sbjct: 573 VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSA 632
Query: 1991 QFTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILL--DVNDN 2047
F + G + + + D ES YN V IP F ++I+ D NDN
Sbjct: 633 MFGIRPYTGWIYLRRQFDYESTQTYNFRV----FAWIPEDGFLQNVSTTVIVRVWDENDN 688
Query: 2048 PPTFLSPKLTYIPENTPIDT-VVFKAQATDPDSGPNSYIEYTLLN------------PLG 2094
PTFL L E +P+ V+ K A D DSG N + Y LL+ P G
Sbjct: 689 SPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGKFFKMNPNTGPAG 748
Query: 2095 NKFSIGTIDGEVRLTGE-------------------------------LDREEVSNYTLT 2123
+ I DG +G LDRE ++ +T
Sbjct: 749 TIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDREHRGHHEMT 808
Query: 2124 VVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDI----IQVFAA 2179
V+ TD+G P +++ V V V DINDN P F Q L E++ L G + VFA
Sbjct: 809 VLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAK 868
Query: 2180 DGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPR 2239
D DEG N +V Y + + +++ F+ID+ G I L + P+Y ++V ATD+G P
Sbjct: 869 DPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRMSVIATDQGVPPL 928
Query: 2240 TDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDD--DRGSNSKLSY 2297
+ V+I ++ ++ + + + +PENL P I+ ++ D + N KL +
Sbjct: 929 QGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLK--PTKIMSLIKSSDHLQQHYNGKLHF 986
Query: 2298 VLFGGNEDNAFTL-SASGELGVTQSLDRETKERFVLMITATD-SGSPALTGTGTINVIVD 2355
+ ++D F + S++G+L +++ LD ET ++ + TD S + +L+ T +++ V+
Sbjct: 987 SIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLSIDVE 1046
Query: 2356 DVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADAS-KNAVIRII-----GGNSQFT 2409
D ND+ P+F + ++ E+ P GT V + NA D D S N+ I+ G + F
Sbjct: 1047 DQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGTNPFL 1106
Query: 2410 INPSTGQIITSALLDRETKDNYTLVVVCSDAG---SPEPLSSSTSVLVTVTDVNDNPPRF 2466
I+PS G ++T + LDRE+ L V SD + L S T+ +V + DVND+ P F
Sbjct: 1107 IHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIV-ILDVNDHNPTF 1165
Query: 2467 QHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRNSEKFHIDPLRGAIMAA 2525
P H+ GS V +T D D G N ++ YS LSG + F +D G +
Sbjct: 1166 ISFPNA-HVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLTTT 1224
Query: 2526 GPLNGASEVT--FSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPV 2582
PL+ + +V D G+ + S T+TV ++ D P + ENQ
Sbjct: 1225 CPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNP 1284
Query: 2583 SSLVTTITG---SSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWI 2639
VT + S + + I G F+I+ TG+V + LD E + + + +
Sbjct: 1285 GEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINSDTGEVVTTTILDREIQEVFTLRV 1344
Query: 2640 EARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGP 2699
RDGGFP SS + TV D ND+AP F + E+LEN P + TV A D D+G
Sbjct: 1345 LVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQEPEVVYTVLASDMDAGN 1404
Query: 2700 NGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
N ++Y I++GN + F+IN +GE+ + R LDRE++S++ L I SD G P +S+ + +
Sbjct: 1405 NRAVEYHIIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHL 1464
Query: 2760 MINILDENDNAPRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMD-ASLP 2817
+ +LD ND++P F + + + V E++ +G V ++ D+D G+N + Y + D AS
Sbjct: 1465 QVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGA 1524
Query: 2818 FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVT----IFVTDINDNAPRFS 2873
FTI+P +G + S L+RE ++ A D S T ++VTD+NDN P
Sbjct: 1525 FTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLE 1584
Query: 2874 RTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQIL 2933
+ + + + V A D D G NG V + F I+ TGEI +Q
Sbjct: 1585 QNPFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDKYTGEIQFQQNP 1644
Query: 2934 KYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVT 2993
+ + + + +D+G P+ + + I+ ++ D F Y VT
Sbjct: 1645 SSEYFPIWLQLKV---------TDQGIPARTTTGLLVIH-MEGEDVKISFSHHLYKGLVT 1694
Query: 2994 KNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISD--L 3051
+N + GT ++ V A + ++Y I + N G L + +G ++V D +
Sbjct: 1695 ENCEAGTSIVTVKAFAPD--SIQDSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEV 1752
Query: 3052 NQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
+ V A+ G+ + V + + +EN ++P F QS A++ ES + V V
Sbjct: 1753 RNEVQLIVLAESSGH---RAYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQV 1809
Query: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
A D D+ +NGLI+YSI SGN+E F I++ +G++T LDYEL + + + A D G
Sbjct: 1810 FATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGM 1869
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAY 3231
+ + V V D+NDN+P FL + + E++ G V H++ D D + + ++
Sbjct: 1870 PRLSNTTVIKVQVTDINDNAPAFLPSEAV-EITEDSLPGVIVTHVSVHDVDLNSAFIFSF 1928
Query: 3232 TVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGT 3291
+S+ F ID NTGV+ LDFE Y L ++ + D + + +++
Sbjct: 1929 AKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELLIQ---ISDSVHYTEGALVVRVLDV 1985
Query: 3292 NEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKK 3351
N+ P F Y + E+ P G V + S DL ++ + Y I +S K F I+ K
Sbjct: 1986 NDNPPVFSQDFYQVTVPESIPVGYSV--LTLSATDLESNENISYRILSSS--KEFSIDPK 2041
Query: 3352 TGQIY-VSGILDREKEERVSLKVLAKNFGSIRGADIDEVT-VNVTVLDAND-PPIFTLNI 3408
G I+ +S +L + V A + G+ D+ +T V + + D N+ P FT+
Sbjct: 2042 NGTIFTISPVLLLDTISTTQFLVEASDGGN---PDLRALTLVEIGIEDMNNYAPEFTVKS 2098
Query: 3409 YSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSIN----------PQ 3458
Y++ +SE +G+ + S D D + Y I SGN F + Q
Sbjct: 2099 YNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQ 2158
Query: 3459 TGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--VSEGE 3516
G + + LDRE + L +LA DSG P + +A + + + D+NDN P +
Sbjct: 2159 VGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTH 2218
Query: 3517 VMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQ 3576
V E+ G+ + + + D D + Y ++S ++ GVL + +D E+
Sbjct: 2219 VKESTPLGSHITVVSANDRD-TGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEK 2277
Query: 3577 IADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQ 3613
+ F L+V D+ S V ++V+D ND+ Q
Sbjct: 2278 MTKFTLTVQASDAEKKHF-SFAVVFVSVLDDNDHAPQ 2313
Score = 677 bits (1746), Expect = 0.0
Identities = 635/2235 (28%), Positives = 1015/2235 (45%), Gaps = 214/2235 (9%)
Query: 259 VPEDAVVGSSVLQVAAADADEGTNADIRYRLQ--DEGTPFQMDPETGLITVREPLDFEAR 316
VPED+ +G+ A ++ I YR+ D G F + P G I R+PLD E +
Sbjct: 390 VPEDSPIGT-----VKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQ 444
Query: 317 RQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTV 376
LTVQA P+ + E I ++DVNDN P F TS + + GT
Sbjct: 445 PVVVLTVQAQLGSAPACSS-TEVNITVMDVNDNHPA-----FLRTSDEIRISQTTPPGTA 498
Query: 377 VALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNL 436
+ L D DS NG I I + F + + L ++ + +L L
Sbjct: 499 LYLARAEDRDS-GRNGLIRYSI-ASPQPGVFAIDRA----LGVLFLNGSLGAGEQRELTL 552
Query: 437 TVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPP--VFSQQVYRVNLSEEAPPGSYV 494
T+ D G QA V ++VI + +H P F VY+V +SE P + +
Sbjct: 553 TLRAEDQ-----GVHPQAALLVLTVVI---EKREHSPSWTFEHLVYQVEVSESLSPMTQM 604
Query: 495 SGISATD-GDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNIS 553
A G + LRYS+ F I ++G + + +
Sbjct: 605 LQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAW 664
Query: 554 ARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSV--VENAPTGTELL-MLRATDG 610
+ G VS ++V + D ND P F +DV VE +P ++ + A D
Sbjct: 665 IPEDGFLQNVS-TTVIVRVWDENDNSPTFL----HDVLFLKVEESPVPQGVIGKITAIDM 719
Query: 611 DLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTIS------------------------- 645
D G NG + + L +D + F+++P +G TI
Sbjct: 720 DSGKNGQLLYFLL---SDGKFFKMNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQA 776
Query: 646 -------------------SLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNS 686
+LDRE + + + VL TD GSPP+++ + VS+ DINDN
Sbjct: 777 FVLKSLFCELGEGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNR 836
Query: 687 PVFYP-----VQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRS-RFQVNA 740
P F+P + + E +P +TTV A DPD G N V YS+S+ D S F+++A
Sbjct: 837 P-FFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDA 895
Query: 741 QSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSF 800
+G I T L + + +Y++ ++ATD G QA+V I V+ + SQ
Sbjct: 896 NNGEIRTTTILSYDYRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHL 955
Query: 801 VVFENVALGYHVGSVSAS---TMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDRE 857
++ EN+ + + +S N + + I D+ G F I+ TG L + +D E
Sbjct: 956 IIPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYE 1015
Query: 858 EQSFYQLKVVASGG----TVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIF 913
S Y +V+ + +++ ++I V+D ND+SP F + ++V EN G ++
Sbjct: 1016 TTSHYLFRVITTDHSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVY 1075
Query: 914 QAKAVDPDEG-VNGMVLYSLK-QNP-KNLFAINEKNGTISLLGPLDVHA-GSYQIEILAS 969
A D D +N + Y ++ NP N F I+ GT+ + LD + + + + AS
Sbjct: 1076 VFNAKDDDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVILTVTAS 1135
Query: 970 DMGV---PQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSG 1026
D V + S+ + + DVND++P F + E V S + A D D G
Sbjct: 1136 DQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFP-NAHVKEDVTVGSLVHHITAHDPDEG 1194
Query: 1027 ANGEIAYTIAEGNTGDAFGI-FPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVN 1085
NG++ Y+I GN F + G L LD E++ +++L V+A D LS++
Sbjct: 1195 RNGKVTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQT 1254
Query: 1086 VTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRY------SF 1139
+TV + DVND P+F Y +E Q G FV +V A+D+D G N ++++ SF
Sbjct: 1255 LTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASF 1314
Query: 1140 EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVY 1199
E+ FE+++ +GE+ T DRE VF+ V+ D G P L T+
Sbjct: 1315 EL----FEINSDTGEVVTTTILDREI------QEVFTLRVLVRDGGFPS-LSSTTTILCT 1363
Query: 1200 MKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFA 1259
++D ND+AP+F+ Y + E+ V V ASD+D GNN + Y II GN + F
Sbjct: 1364 VEDENDHAPEFIVSSYDIEVLEN-QEPEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFT 1422
Query: 1260 IDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKST 1319
I+ SG+++ LD E ++LVI D G P +S L + +LD ND++PSFP
Sbjct: 1423 INEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLY 1482
Query: 1320 LFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLD 1379
V E+ +G +V ++A D D G N Y +T + G F+I P +G++ + LD
Sbjct: 1483 YQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEAS-GAFTIDPMSGTLKTSNTLD 1541
Query: 1380 FETQSLYKLNITAKDQG-RPPRSSTMSVVIHVRDFNDNPPSFP--PGDIFKSIVENIPIG 1436
E +S + + A+D + RS+T+ + ++V D NDN P P D+F S P
Sbjct: 1542 REARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLS--PESPTN 1599
Query: 1437 TSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTV 1496
+ + V A D D NG + ++ + + F+ID+ G I E+ ++ L +
Sbjct: 1600 QTTVIVRADDLDLGPNGTVVFSFAETQ---SMFSIDKYTGEIQFQQNPSSEYFPIW-LQL 1655
Query: 1497 KANDQAVPIETRRYALKNVTILVTDL-NDNVPMFISQNAL--AADPSAVIGSVLTTIMAA 1553
K DQ +P T +LV + ++V + S + + G+ + T+ A
Sbjct: 1656 KVTDQGIPART------TTGLLVIHMEGEDVKISFSHHLYKGLVTENCEAGTSIVTVKAF 1709
Query: 1554 DPDEGANGEIEYEIINGDTDTFI-VDRYSGDLRVASALVPSQLIYN---LIVSATDLGPE 1609
PD ++Y I +G+ D + + SG L V + N LIV A G
Sbjct: 1710 APD-SIQDSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSG-- 1766
Query: 1610 RRKSTTELTIILQ--GLDGPVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYY 1666
++ ++ +++Q + P F Q Y + E + +VI + A G +EY
Sbjct: 1767 -HRAYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYS 1825
Query: 1667 IVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEV 1726
I+S EE F I +G+I T AILD E + L+ V A +K PR V
Sbjct: 1826 ILSGNQEE-----AFQIDALSGVITTKAILDYELTSSYSLI-VQATDK--GMPRLSNTTV 1877
Query: 1727 -EITLQDINDNPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGAD 1784
++ + DINDN P F P++ +++T E+ G + ++ D D + + ++ S
Sbjct: 1878 IKVQVTDINDNAPAFLPSEAVEIT--EDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPG 1935
Query: 1785 DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRP 1844
F ID +G ++ + LD E ++Y LL++ D + ++ + + V DVND+ P FS+
Sbjct: 1936 TKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVLDVNDNPPVFSQD 1995
Query: 1845 VYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITG-VFNLTRL 1903
Y +PE G V + ATD +S N I+Y + ++ F ++P G +F ++ +
Sbjct: 1996 FYQVTVPESIPVGYSVLTLSATDLES--NENISYRILSSSKE--FSIDPKNGTIFTISPV 2051
Query: 1904 LDYEVQQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGS 1961
L + V A DGG V I D+N+ P F++ SY+ SL E+ VGS
Sbjct: 2052 LLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGS 2111
Query: 1962 TVLVFNVTDAD-DGINSQLTYSIASGDSLGQFTVDKN-----------GVLKVLKALDRE 2009
T++ F+ D D N+ + YSI SG+S F V+ G L +L +LDRE
Sbjct: 2112 TLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDRE 2171
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL-TYIPENTPIDTV 2068
+ + + LV+ D P S STA +SI +LDVNDNPP F S T++ E+TP+ +
Sbjct: 2172 ASASHELVILASDSGCPPLS---STAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSH 2228
Query: 2069 VFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNYTLTVV 2125
+ A D D+G ++ I Y +++ GN+ F + G + L LD E+++ +TLTV
Sbjct: 2229 ITVVSANDRDTGSHAEIIYNIIS--GNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQ 2286
Query: 2126 ATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGT 2185
A+D + S + V V VLD ND+ P F + + + EN + I + A D D G
Sbjct: 2287 ASDAEKKHFSFAV-VFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGP 2345
Query: 2186 NGQVRYGIVN--------GNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGST 2237
G++ Y IV+ + F ID +TG I + LD E Y LTVQA D+G
Sbjct: 2346 YGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGDA 2405
Query: 2238 PRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSY 2297
T + V + + I++F P+F Y +PE + I +V A D D G + + Y
Sbjct: 2406 --TASLVVWVDIEGIDEFEPIFTQDQYFFTLPEK-NKDRQLIGRVEASDADAGIDGVILY 2462
Query: 2298 VL------FGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTIN 2351
L F N+ N + L++E ++ + S S + T +N
Sbjct: 2463 SLGTSSPFFSVNKTNGNIYLIRALPLIKSQLNKEDTLEMKIIAHSPKSDSKFASCTVFVN 2522
Query: 2352 VIVDDVNDNVPTFAS 2366
V + FAS
Sbjct: 2523 VSFSSEGTPLAVFAS 2537
Score = 676 bits (1743), Expect = 0.0
Identities = 597/1992 (29%), Positives = 926/1992 (46%), Gaps = 187/1992 (9%)
Query: 75 SESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP------TYPTEVRVLVRDL 128
S A+F I TG +Y D ES + N V + P T V V V D
Sbjct: 628 SVDSAMFGIRPYTGWIYLRRQFDYES--TQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDE 685
Query: 129 NDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGV-------DHRSYRI----- 176
NDN+P F + + +E + TA D D G NG D + +++
Sbjct: 686 NDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGKFFKMNPNTG 745
Query: 177 -----------------------IRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVT 213
+E F L GEG ++ V+ LDRE
Sbjct: 746 PAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVA---LDREHR 802
Query: 214 PQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVF----GSSHYQAGVPEDAVVGSSV 269
+++ V V D+G P R + V V+V DINDN P F V E V V
Sbjct: 803 GHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLV 862
Query: 270 LQVAAADADEGTNADIRYRL--QDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMD 327
V A D DEG NA++ Y + +D F++D G I L ++ R Y ++V A D
Sbjct: 863 TTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRMSVIATD 922
Query: 328 RGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADS 387
+GVP L G+A IQ++ ++ ++ R+ + EN + +++L+ +D
Sbjct: 923 QGVPPLQGQAVVNIQVIPLSKGRAIMS-----QNIRHLIIPENLKPTKIMSLIKSSDHLQ 977
Query: 388 PAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAP 447
NG + I+ ++ HFE+ SS +L L K LD E Y V +D+
Sbjct: 978 QHYNGKLHFSIVADDKDGHFEIDSS-TGDLFLSK---ELDYETTSHYLFRVITTDH---- 1029
Query: 448 PGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGD-SGL 506
+ + SS L I V D NDH P F ++ +++ E P G+ V +A D D S L
Sbjct: 1030 --SKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFL 1087
Query: 507 NANLRYSIVSGN-GLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVH---PK 562
N+ ++Y I S N G F I G + T S LDRE ++L ++A DQ V+ +
Sbjct: 1088 NSRIQYYIESHNPGTNPFLIHPSFGTLVTVSR--LDRESIPTVILTVTASDQAVNVTDRR 1145
Query: 563 VSYAQLVVTLLDVNDEKPVF-SQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFS 621
+ + +LDVND P F S P + V E+ G+ + + A D D G NG V +S
Sbjct: 1146 LRSLTAQIVILDVNDHNPTFISFPNAH---VKEDVTVGSLVHHITAHDPDEGRNGKVTYS 1202
Query: 622 LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+ + +F LD SG L+T LD E + + L VLA D G+P SS + V++LD
Sbjct: 1203 ILSG-NENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLD 1261
Query: 682 INDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAG-DRSRFQVNA 740
+ND +PVF Y A +KEN+ G ++T V A D D G N +++ I G F++N+
Sbjct: 1262 VNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINS 1321
Query: 741 QSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSF 800
+G + T LDRE + + L+++ DGG + + TV D D+ P F +Y
Sbjct: 1322 DTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDI 1381
Query: 801 VVFENVALGYHVGSVSASTMDLNSN--ISYLITTGDQKGMFAINQVTGQLTTANVIDREE 858
V EN V +V AS MD +N + Y I G+ F IN+++G+L+T +DRE+
Sbjct: 1382 EVLENQEPEV-VYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSGELSTTRALDREQ 1440
Query: 859 QSFYQLKVVASG-GTVTGDTMVNITVK--DLNDNSPHFLQAIESVNVVENWQAGHSIFQA 915
S + L ++ S G +++++ V+ D ND+SP F +V E+ + G +
Sbjct: 1441 ISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVL 1500
Query: 916 KAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGS-YQIEILASDMGVP 974
AVD DEG+NG Y L F I+ +GT+ LD A S + +A D +
Sbjct: 1501 SAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQ 1560
Query: 975 -QLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAY 1033
S++VI+ VYV DVNDN PV +Q ++V LS P N V+A D D G NG + +
Sbjct: 1561 GSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVF 1620
Query: 1034 TIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILED 1092
+ AE T F I G++ + E + L + +D+ + P T + VI +
Sbjct: 1621 SFAE--TQSMFSIDKYTGEIQFQQNPSSEYFPIW-LQLKVTDQGI-PARTTTGLLVIHME 1676
Query: 1093 VNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD--FELHA 1150
D + F+ Y E AG+ + V A D ++YS D L +
Sbjct: 1677 GEDVKISFSHHLYKGLVTENCEAGTSIVTVKAFAPD-SIQDSMKYSIFSGNEDGVLSLCS 1735
Query: 1151 ISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKF 1210
SG++T + +R V+A G + V V ++D NDN+P F
Sbjct: 1736 KSGQLTVKEPKFLDFEVRNE----VQLIVLAESSG----HRAYCKVAVLIQDENDNSPCF 1787
Query: 1211 LKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLI 1270
+ YQA++SES V++V A+D+D G NGLI YSI+ GN+E F ID+ SG +T
Sbjct: 1788 EQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTK 1847
Query: 1271 GKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRI 1330
LDYE T +YSL++QA D G L++T + + + D NDN P+F S V++ E+
Sbjct: 1848 AILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAFLPSEA-VEITEDSLP 1906
Query: 1331 GELVSSVTATDSDSGDNADLYYSITGTNNHGT-FSISPNTGSIFLAKKLDFETQSLYKLN 1389
G +V+ V+ D D N+ +S +N GT F+I NTG + L K LDFE + Y+L
Sbjct: 1907 GVIVTHVSVHDVDL--NSAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELL 1964
Query: 1390 ITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDA 1449
I D + ++V+ V D NDNPP F ++ E+IP+G SV++++A D
Sbjct: 1965 IQISDS---VHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLTLSA--TDL 2019
Query: 1450 DINGQLSYTIIQQMPRGNHFTIDEVKGTIYT-NAEIDREFANLFELTVKANDQAVPIETR 1508
+ N +SY I+ F+ID GTI+T + + + + + V+A+D P + R
Sbjct: 2020 ESNENISYRILSS---SKEFSIDPKNGTIFTISPVLLLDTISTTQFLVEASDGGNP-DLR 2075
Query: 1509 RYALKNVTILVTDLNDNVPMF-ISQNALAADPSAVIGSVLTTIMAADPD-EGANGEIEYE 1566
AL V I + D+N+ P F + L+ A++GS L T D D N +EY
Sbjct: 2076 --ALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYS 2133
Query: 1567 IINGDT-DTFIVD----------RYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKST 1614
II+G++ + F V+ + G L + +L + + L++ A+D G ST
Sbjct: 2134 IISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSST 2193
Query: 1615 TELTI-ILQGLDGPV-FTQPKYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYYIVSVR 1671
++I +L D P F+ Y T +KE P+G+++ + A GS A + Y I+S
Sbjct: 2194 AVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEIIYNIIS-- 2251
Query: 1672 CEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAE------ 1725
EK F + +TG+ LYL+ EK T F T +A
Sbjct: 2252 GNEK---GHFYLEENTGV--------------LYLIKPLDYEKMTKFTLTVQASDAEKKH 2294
Query: 1726 -----VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTII 1780
V +++ D ND+ P F V EN+ S I + A+D D G +TY+I+
Sbjct: 2295 FSFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIV 2354
Query: 1781 SGA---------DDSFRIDPESGDLIATRRLDRERRSKYSLLVRA-DDGLQSSDMRINIT 1830
S D F IDP +GD+ A + LD E +KY L V+A D G ++ + + +
Sbjct: 2355 SPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGDATASLVVWVD 2414
Query: 1831 VSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFF 1890
+ +++ P F++ Y F +PE L+ + A+D D+G++G I Y + F
Sbjct: 2415 IEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSLGTSSP--FFS 2472
Query: 1891 LNPITGVFNLTRLLDYEVQQY-------YILTVRAEDGGGQFTTIRVYFNILDVNDNPPI 1943
+N G L R L Q + + +F + V+ N+ ++ P+
Sbjct: 2473 VNKTNGNIYLIRALPLIKSQLNKEDTLEMKIIAHSPKSDSKFASCTVFVNVSFSSEGTPL 2532
Query: 1944 -FSLNSYSTSLM 1954
+S+S SL+
Sbjct: 2533 AVFASSFSISLV 2544
Score = 651 bits (1679), Expect = 0.0
Identities = 657/2490 (26%), Positives = 1090/2490 (43%), Gaps = 232/2490 (9%)
Query: 1221 ESAANLTQVLRVSASDVDEGNNGLIHYSIIKG----NEERQFAIDSTSGQVTLIGKLDYE 1276
E A + V+ASD D G G I YS+ G + F ID GQ+ + +D E
Sbjct: 68 EENAKPVKETEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRE 127
Query: 1277 ATPA-YSLVIQAVDSGTIP----------LNSTCTLNIDILDENDNTPSFPKSTLFVDVL 1325
PA Y L+++A D L++ + +D+ D NDN P F ST +
Sbjct: 128 RDPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSIS 187
Query: 1326 ENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSL 1385
+ + G + +V ATD DSG + Y + N F+I TG E + L
Sbjct: 188 DETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGLY------SPEVEIL 241
Query: 1386 YKLNITAKDQGRPPRSSTMSVVIHVRDFN-DNPPSFPPGDIFKSIVENIPIGTSVISVTA 1444
+N +A + + ++ H + D + + + + +
Sbjct: 242 SAVNFSADKEVMNSLEMFLPLLRHFKKVERDEEAAEKKFEASRGWFMRFKGRRHLHYLKV 301
Query: 1445 HDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVP 1504
D A +G+ + + + + + E G IY + + L V A D
Sbjct: 302 QDEAASADGEAAARYVANLAK----ILGE--GIIYLTLPLSHLESTTLSLMVSAQDGGG- 354
Query: 1505 IETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLTTIMAAD-PDEGANGEI 1563
L +N +V + I Q LA P+ T ++ D P++ G +
Sbjct: 355 -------------LTAVINADVTIHIFQTTLA--PAEFERPKYTFLVYEDVPEDSPIGTV 399
Query: 1564 E------------YEIINGDTD-TFIVDRYSGDLRVASALVPSQLIYNLIVSATDLGPER 1610
+ Y I +GD F + G +R L ++ LG
Sbjct: 400 KAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQLGSAP 459
Query: 1611 RKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYYI 1667
S+TE+ I + ++ P F + + + P GT + A G + Y I
Sbjct: 460 ACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSI 519
Query: 1668 VSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVE 1727
S + +F I R G++ L + L L E P+ +
Sbjct: 520 ASPQ------PGVFAIDRALGVLFLNGSLGAGEQRELTLT--LRAEDQGVHPQAALLVLT 571
Query: 1728 ITLQDINDNPP-VFPTDMLDLTVEENIGDGSKIMQLTAMD-ADEGANALVTYTIISGADD 1785
+ ++ +P F + + V E++ ++++Q A + A + + Y++ D
Sbjct: 572 VVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDS 631
Query: 1786 S-FRIDPESGDLIATRRLDRERRSKYSLLVRA---DDG-LQSSDMRINITVSDVNDHTPK 1840
+ F I P +G + R+ D E Y+ V A +DG LQ+ + + V D ND++P
Sbjct: 632 AMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNSPT 691
Query: 1841 FSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITG---- 1896
F V + E +P ++ I A D DSG NG++ Y + D + F +NP TG
Sbjct: 692 FLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGK--FFKMNPNTGPAGT 749
Query: 1897 --------------------------VFNLTRL--------------LDYEVQQYYILTV 1916
F L L LD E + ++ +TV
Sbjct: 750 IYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDREHRGHHEMTV 809
Query: 1917 RAEDGGG--QFTTIRVYFNILDVNDNPPIFSL----NSYSTSLMENLPVGSTVLVFNVTD 1970
D G + T+ VY ++ D+NDN P F ++E PV V D
Sbjct: 810 LVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKD 869
Query: 1971 ADDGINSQLTYSIASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPAS 2029
D+G N+++TYS++S DS F +D NG ++ L + + Y + V D +P
Sbjct: 870 PDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRMSVIATD-QGVPPL 928
Query: 2030 RFTSTAQVSIILLDVNDNPPTFLSPKLTY--IPENTPIDTVVFKAQATDP-DSGPNSYIE 2086
+ + + +I L +S + + IPEN ++ +++D N +
Sbjct: 929 QGQAVVNIQVIPLSKGR---AIMSQNIRHLIIPENLKPTKIMSLIKSSDHLQQHYNGKLH 985
Query: 2087 YTLL-NPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQP-SLSSSTEVVVMV 2144
++++ + F I + G++ L+ ELD E S+Y V+ TD + SLSS+ + + V
Sbjct: 986 FSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLSIDV 1045
Query: 2145 LDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGT--NGQVRYGIVNGNTNQE- 2201
D ND++P F L + + EN GT ++ VF A D+G+ N +++Y I + N
Sbjct: 1046 EDQNDHSPSFQDELIVISVEENVPIGT-LVYVFNAKDDDGSFLNSRIQYYIESHNPGTNP 1104
Query: 2202 FRIDSVTGAITVAKPLDREKTPTYHLTVQATDRG---STPRTDTSTVSIVLLDINDFVPV 2258
F I G + LDRE PT LTV A+D+ + R + T IV+LD+ND P
Sbjct: 1105 FLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPT 1164
Query: 2259 FELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGELG 2317
F P + +V E++ T+ + + A D D G N K++Y + GNE+ F L +SG L
Sbjct: 1165 FISFP-NAHVKEDV-TVGSLVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDESSGLLT 1222
Query: 2318 VTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDA 2377
T LD E K + +L + A D G+PAL+ + T+ V V DVND P F Y ++ E+
Sbjct: 1223 TTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQ 1282
Query: 2378 PTGTDVLLVNASDADASKNAVIR--IIGGNS--QFTINPSTGQIITSALLDRETKDNYTL 2433
G V V A D D+ N+ ++ I+ G S F IN TG+++T+ +LDRE ++ +TL
Sbjct: 1283 NPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINSDTGEVVTTTILDREIQEVFTL 1342
Query: 2434 VVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDA 2493
V+ D G P LSS+T++L TV D ND+ P F Y + P V+ V +D
Sbjct: 1343 RVLVRDGGFPS-LSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQEP-EVVYTVLASDM 1400
Query: 2494 DIGPNSELHYSL-SGRNSEKFHIDPLRGAIMAAGPLNGA--SEVTFSVHVKDGGSFPKTD 2550
D G N + Y + G E F I+ + G + L+ S T + D G P++
Sbjct: 1401 DAGNNRAVEYHIIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSS 1460
Query: 2551 STTVTVRFVNKADF-PKVRAKEQTFMFPENQPVSSLVTTITG----SSLRGEPMSYYIAS 2605
+ VR ++ D P E+ V ++V ++ L G+ + Y +
Sbjct: 1461 VIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQ--TEYFLT 1518
Query: 2606 GNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKL-DITVLDVND 2664
F ID ++G + S LD E ++ ARD S + + V DVND
Sbjct: 1519 DEASGAFTIDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVND 1578
Query: 2665 NAPIFKEDPFISEILENLSPRKILTV--SAMDKDSGPNGQLDYEIVNGNMENSFSINHAT 2722
N P+ +++PF L SP TV A D D GPNG + + ++ FSI+ T
Sbjct: 1579 NDPVLEQNPF-DVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFAE--TQSMFSIDKYT 1635
Query: 2723 GEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
GEI+ + E + L +K +D+G P+++T+ ++I++ E+ ++ V
Sbjct: 1636 GEIQFQQNPSSEYFPIW-LQLKVTDQGIPARTTTGLLVIHMEGEDVKISFSHHLYKGLVT 1694
Query: 2783 ENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTIN--PSTGDIVISRP--LNREDT 2838
EN G ++ V D I +YSI + ++ +G + + P L+ E
Sbjct: 1695 ENCEAGTSIVTVKAFAPD-SIQDSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVR 1753
Query: 2839 DRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATD 2898
+ ++ V A SG V + + D NDN+P F ++ Y E + V QVFATD
Sbjct: 1754 NEVQLIVLAESSGHRAYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATD 1813
Query: 2899 PDEGSNGQVFYFIKS--QSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSS 2956
D G NG + Y I S Q E F+I+A +G I K IL Y+ + +S IV ++
Sbjct: 1814 LDSGLNGLIEYSILSGNQEEAFQIDALSGVITTKAILDYELTSSYS--------LIVQAT 1865
Query: 2957 DRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLN 3016
D+G P L + T + + + D NDNAP FL S+ +T++ G + VT + D LN
Sbjct: 1866 DKGMPRLSNTTVIKVQVTDINDNAPAFLPSEA-VEITEDSLPG---VIVTHVSVHDVDLN 1921
Query: 3017 SEVEYFISNDNHLG-KFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATV 3075
S + + +++ G KF +D +TG + + +L + + + + D + ++ +
Sbjct: 1922 SAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSVH---YTEGAL 1978
Query: 3076 HITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEG 3135
+ V + N + P FSQ T+PES +G V T+SA D ++ N I Y I S ++E
Sbjct: 1979 VVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLESNEN--ISYRILSSSKE- 2035
Query: 3136 IFAINSSTG-ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVF 3194
F+I+ G I T++ L + + + A DGG V + + D+N+ +P F
Sbjct: 2036 -FSIDPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEF 2094
Query: 3195 LSDDYFPTVLENAPSGTTVIHLNATDAD-SGTNAVIAYTVQSSDS-DLFVIDPN------ 3246
Y ++ E+A G+T++ + D D + N + Y++ S +S + F ++
Sbjct: 2095 TVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEY 2154
Query: 3247 ----TGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKL 3302
G + LD E S+ L + A + S A ++IQ+ N+ P F S
Sbjct: 2155 PYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLS 2214
Query: 3303 YYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILD 3362
Y+ + E+ P G+ + V A+DRD G+ E+ Y I + K F + + TG +Y+ LD
Sbjct: 2215 YHTHVKESTPLGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLD 2274
Query: 3363 REKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGT 3421
EK + +L V A + V V+VLD ND P F + +S + E +PI +
Sbjct: 2275 YEKMTKFTLTVQASD---AEKKHFSFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISS 2331
Query: 3422 HVTFVSAFDSDSIPSWSRFSYFI--------GSGNENGAFSINPQTGQITVTAELDRETL 3473
+ ++A D D+ P + +Y I G ++ F I+P TG I LD E
Sbjct: 2332 TICSINALDFDAGP-YGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENG 2390
Query: 3474 PIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSE--GEVMENKRPGTLVMTLQ 3531
Y L+V A D G AT S + V +E I++ P+ T + + E + L+ ++
Sbjct: 2391 NKYCLTVQAKDKG--DATASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVE 2448
Query: 3532 STDPDLPPNQGPFTYYLLSTGPATSYFSLS 3561
++D D G L S G ++ +FS++
Sbjct: 2449 ASDAD----AGIDGVILYSLGTSSPFFSVN 2474
Score = 625 bits (1613), Expect = e-178
Identities = 607/2236 (27%), Positives = 1002/2236 (44%), Gaps = 210/2236 (9%)
Query: 45 PRQVFQVLEEQPPGTLVGTIQTRPGFT------YRLSESH--ALFAINSSTGALYTTSTI 96
P+ F V E+ P + +GT++ R YR+S F+I+ G + T +
Sbjct: 380 PKYTFLVYEDVPEDSPIGTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPL 439
Query: 97 DRESLPSDVINLVV-LSSAPTYP-TEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQV 154
D E+ P V+ + L SAP TEV + V D+NDN P F S + + + G +
Sbjct: 440 DHETQPVVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTAL 499
Query: 155 ILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTP 214
L A D D G NG+ S I + G F +D L FL+ G RE+T
Sbjct: 500 YLARAEDRDSGRNGLIRYS---IASPQPGVFAIDRALGV----LFLNGSLGAGEQRELT- 551
Query: 215 QYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPP-VFGSSHYQAGVPEDAVVGSSVLQVA 273
L + ED+G + L + V ++ +P F YQ V E + +LQ
Sbjct: 552 ---LTLRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQ 608
Query: 274 AAD-ADEGTNADIRYRLQD--EGTPFQMDPETGLITVREPLDFEARRQYSLTVQAM---D 327
A + + +RY L+ + F + P TG I +R D+E+ + Y+ V A D
Sbjct: 609 AHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPED 668
Query: 328 RGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADS 387
+ +++ ++++ D NDN P F + V+E+ V+ +T D DS
Sbjct: 669 GFLQNVS--TTVIVRVWDENDNSPT-----FLHDVLFLKVEESPVPQGVIGKITAIDMDS 721
Query: 388 PAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVAS----------------------- 424
NG + +L + + + +I A
Sbjct: 722 -GKNGQLLYFLLSDGKFFKMNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLK 780
Query: 425 ---------------ALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIN 469
ALDRE + +TV V+D G+PP R++ ++ + V DIN
Sbjct: 781 SLFCELGEGELINWVALDREHRGHHEMTVLVTDR-GSPP------RNATMAVYVSVTDIN 833
Query: 470 DHPPVFSQ----QVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
D+ P F Q + V + E P V+ + A D D G NA + YS+ S + F I
Sbjct: 834 DNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKI 893
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQP 585
++G + T + L + +++ A DQGV P A + + ++ ++ + + SQ
Sbjct: 894 DANNGEIRTTTI--LSYDYRPSYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQN 951
Query: 586 EGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTIS 645
+ + PT L+ + NG + FS+ + D F +D +G L
Sbjct: 952 IRHLIIPENLKPTKIMSLIKSSDHLQQHYNGKLHFSIVADDKDGH-FEIDSSTGDLFLSK 1010
Query: 646 SLDREEQAFYSLLVLATDLG-SPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPG 704
LD E + Y V+ TD + SS +++ + D ND+SP F ++EN P
Sbjct: 1011 ELDYETTSHYLFRVITTDHSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPI 1070
Query: 705 GSYITTVSATDPDLG-TNGTVKYSISAGD--RSRFQVNAQSGVISTRMALDREEKTAYQL 761
G+ + +A D D N ++Y I + + + F ++ G + T LDRE L
Sbjct: 1071 GTLVYVFNAKDDDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVIL 1130
Query: 762 QIVATDGG-NLQSPNQAIVT--ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSAS 818
+ A+D N+ +T I +LD D+ P F + V E+V +G V ++A
Sbjct: 1131 TVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFPNAHVK-EDVTVGSLVHHITAH 1189
Query: 819 TMD--LNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA-SGGT--V 873
D N ++Y I +G++ F +++ +G LTT +D E ++ + L V+A GT +
Sbjct: 1190 DPDEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPAL 1249
Query: 874 TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK 933
+ + +TV D+ND +P F Q + +V EN G + + +A+D D GVN + + +
Sbjct: 1250 SSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIM 1309
Query: 934 QNPK-NLFAINEKNGTISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVND 991
LF IN G + LD + + +L D G P LSS+ + V D ND
Sbjct: 1310 PGASFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDEND 1369
Query: 992 NSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DG 1050
++P F SY++ + E++ + V ASD D+G N + Y I +GNT + F I G
Sbjct: 1370 HAPEFIVSSYDIEVLENQEPEV-VYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSG 1428
Query: 1051 QLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFE 1110
+L LDRE + L+++ SD P S+ +++ V + D ND+ P F + Y
Sbjct: 1429 ELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVR 1488
Query: 1111 EEQRAGSFVGKVSAVDKDFGPNGEVRYSF-EMVQPDFELHAISGEITNTHQFDRESLMRR 1169
E+ G+ V +SAVDKD G NG+ Y + F + +SG + ++ DRE+ +
Sbjct: 1489 EDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLKTSNTLDREARSQH 1548
Query: 1170 RGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATIS-ESAANLTQ 1228
+F+ +A D I + VY+ D+NDN P ++ + +S ES N T
Sbjct: 1549 ------TFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTNQTT 1602
Query: 1229 VLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAV 1288
V+ V A D+D G NG + +S + F+ID +G++ E P + L ++
Sbjct: 1603 VI-VRADDLDLGPNGTVVFSF--AETQSMFSIDKYTGEIQFQQNPSSEYFPIW-LQLKVT 1658
Query: 1289 DSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNA 1348
D G IP +T L + ++ D SF V EN G + +V A DS ++
Sbjct: 1659 DQG-IPARTTTGLLVIHMEGEDVKISFSHHLYKGLVTENCEAGTSIVTVKAFAPDSIQDS 1717
Query: 1349 DLYYSITGTNNHGTFSISPNTGSIFL--AKKLDFETQSLYKLNITAKDQGRPPRSSTMSV 1406
+ YSI N G S+ +G + + K LDFE ++ +L + A+ G + V
Sbjct: 1718 -MKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSG---HRAYCKV 1773
Query: 1407 VIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRG 1466
+ ++D NDN P F S+ E+ VI V A D D+ +NG + Y+I+ G
Sbjct: 1774 AVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILS----G 1829
Query: 1467 NH---FTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTIL---VT 1520
N F ID + G I T A +D E + + L V+A D+ +P L N T++ VT
Sbjct: 1830 NQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP------RLSNTTVIKVQVT 1883
Query: 1521 DLNDNVPMFISQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRY 1580
D+NDN P F+ A+ ++ G ++T + D D + + + F +D+
Sbjct: 1884 DINDNAPAFLPSEAVEITEDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQN 1943
Query: 1581 SGDLRVASALVPSQLI-YNLIVSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYI 1635
+G + + L ++ Y L++ +D TE ++++ LD PVF+Q Y
Sbjct: 1944 TGVVVLVKTLDFEEMTEYELLIQISD-----SVHYTEGALVVRVLDVNDNPPVFSQDFYQ 1998
Query: 1636 TILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAA- 1694
+ E P+G +V+++ A +E + Y I+S E F+I G I T +
Sbjct: 1999 VTVPESIPVGYSVLTLSATDLESNE-NISYRILSSSKE-------FSIDPKNGTIFTISP 2050
Query: 1695 --ILDREQGACLYLVDVYAIEKSTAFPRTQRA--EVEITLQDINDNPPVFPTDMLDLTVE 1750
+LD + +E S RA VEI ++D+N+ P F +L++
Sbjct: 2051 VLLLD------TISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLS 2104
Query: 1751 ENIGDGSKIMQLTAMDAD-EGANALVTYTIISG-ADDSFRID----------PESGDLIA 1798
E+ GS ++ + +D D N V Y+IISG + ++F ++ + G L+
Sbjct: 2105 EDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVL 2164
Query: 1799 TRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTI 1855
LDRE + + L++ A D SS I+I V DVND+ P FS Y + E T
Sbjct: 2165 LHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTP 2224
Query: 1856 PGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILT 1915
GS + + A D D+G + EI Y + +E G F+L TGV L + LDYE + LT
Sbjct: 2225 LGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLT 2284
Query: 1916 VRAEDGGGQ-FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDG 1974
V+A D + F+ V+ ++LD ND+ P F +S+S + ENLP+ ST+ N D D G
Sbjct: 2285 VQASDAEKKHFSFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAG 2344
Query: 1975 INSQLTYSIASGDSLGQ--------FTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQ 2025
+LTYSI S L F +D G + + LD E+ + Y L VQ D
Sbjct: 2345 PYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKD--- 2401
Query: 2026 IPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDSGPNSY 2084
T++ V + + +++ P F + + +PE ++ + +A+D D+G +
Sbjct: 2402 --KGDATASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGV 2459
Query: 2085 IEYTLLNPLGNKFSIGTIDGEVRL-------TGELDREEVSNYTLTVVATDKGQPSLSSS 2137
I Y+ L FS+ +G + L +L++E+ + ++A S +S
Sbjct: 2460 ILYS-LGTSSPFFSVNKTNGNIYLIRALPLIKSQLNKED--TLEMKIIAHSPKSDSKFAS 2516
Query: 2138 TEVVVMVLDINDNNPI 2153
V V V ++ P+
Sbjct: 2517 CTVFVNVSFSSEGTPL 2532
Score = 201 bits (510), Expect = 2e-50
Identities = 257/1059 (24%), Positives = 453/1059 (42%), Gaps = 140/1059 (13%)
Query: 2680 ENLSPRKILTVSAMDKDSGPNGQLDYEIVNGNME----NSFSINHATGEIRSVRPLDREK 2735
EN P K V+A D DSG G ++Y + +G + +F I+ G+I + +DRE+
Sbjct: 69 ENAKPVKETEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRER 128
Query: 2736 -VSHYVLTIKSSD------------KGSPSQSTSVKVMINILDENDNAPRFS-QIFSAHV 2781
+ Y L +++ D KG S V+V ++ D NDN P F+ + +
Sbjct: 129 DPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRV--DLEDVNDNHPVFNPSTYVTSI 186
Query: 2782 PENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLP--FTINPSTGDIVISRPLNREDTD 2839
+ + G + V +D+D GI Y ++ ++ FTI+ +TG
Sbjct: 187 SDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTG-------------- 232
Query: 2840 RYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDP 2899
S +V I ++ +N +A + S + P L A +
Sbjct: 233 -------------LYSPEVEI-LSAVNFSADKEVMNSLEMFLPLLRHFKKVERDEEAAEK 278
Query: 2900 D-EGSNGQVFYFI-KSQSEYFRIN----ATTGEIFNKQILKYQNVTG---------FSNV 2944
E S G F + Y ++ + GE + + + G S++
Sbjct: 279 KFEASRGWFMRFKGRRHLHYLKVQDEAASADGEAAARYVANLAKILGEGIIYLTLPLSHL 338
Query: 2945 NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
S +V++ D G + + VTI+I + +F + KY V ++V + +
Sbjct: 339 ESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPIGT 398
Query: 3005 VTAIDDKDFGLNSE--VEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAK 3062
V A + LNS + Y IS+ + GKF + G I L + +TV A+
Sbjct: 399 VKAREP----LNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQ 454
Query: 3063 DKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNG 3122
G+ P S V+ITV + N + P F ++ I ++ G+ + A DRD+ NG
Sbjct: 455 -LGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNG 513
Query: 3123 LIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTV 3182
LI+YSI+S + G+FAI+ + G+L L +L ++ +T+ A D G + +TV
Sbjct: 514 LIRYSIASP-QPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTV 572
Query: 3183 NVIDVNDNSPVFLSDD--YFPTVLENAPSGTTVIHLNATDADSGTNAV-IAYTVQSS-DS 3238
VI+ ++SP + + Y V E+ T ++ A A + Y+++ S DS
Sbjct: 573 -VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDS 631
Query: 3239 DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCS--FATVNIQLKGTNEYVP 3296
+F I P TG I + D+E+ Q+Y+ V A+ +P++ TV +++ N+ P
Sbjct: 632 AMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAW-IPEDGFLQNVSTTVIVRVWDENDNSP 690
Query: 3297 RFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQ-- 3354
F+ + + ++ E+ ++G++ A D D G +G++ Y + + K F++N TG
Sbjct: 691 TFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDG--KFFKMNPNTGPAG 748
Query: 3355 -IYV----------SGI-------------------------------LDREKEERVSLK 3372
IYV SG LDRE +
Sbjct: 749 TIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDREHRGHHEMT 808
Query: 3373 VLAKNFGSI-RGADIDEVTVNVTVLDAND-----PPIFTLNIYSVQISEGVPIGTHVTFV 3426
VL + GS R A + V V+V D ND P V++ EG P+ VT V
Sbjct: 809 VLVTDRGSPPRNATM---AVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTV 865
Query: 3427 SAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSG 3486
A D D + + +Y + S + + F I+ G+I T L + P Y +SV+A D G
Sbjct: 866 FAKDPDEGNN-AEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRMSVIATDQG 924
Query: 3487 TPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPF 3544
P G A + + + ++ +++ + ++ EN +P ++ ++S+D G
Sbjct: 925 VPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSDHLQQHYNGKL 984
Query: 3545 TYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKD-SGVPQMSSTGTVHIT 3603
+ +++ + S+ G L ++E+D E + + V+T D S +SST + I
Sbjct: 985 HFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLSID 1044
Query: 3604 VIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPD 3642
V DQND+ + I ++ N+ G ++ +D D
Sbjct: 1045 VEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDD 1083
Score = 122 bits (306), Expect = 9e-27
Identities = 146/589 (24%), Positives = 245/589 (41%), Gaps = 77/589 (13%)
Query: 3070 SSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIV-------------RTVSARDR 3116
S+ A V+ + N SQ + PE+ G+IV V+A D
Sbjct: 25 STDACVYEVYVKINSIVKSQSQCGLKRGSPETELWGAIVFRSQEENAKPVKETEVTASDA 84
Query: 3117 DAAMNGLIKYSISSG----NEEGIFAINSSTGILTLAKALDYELCQK-HEMTISAIDGGW 3171
D+ + G I+YS+ G F I+ G + +++ +D E +++ + A DG
Sbjct: 85 DSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGDE 144
Query: 3172 VART----------GYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDA 3221
T V V++ DVNDN PVF Y ++ + GT +I++ ATD
Sbjct: 145 QRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQ 204
Query: 3222 DSGTNAVIAYT-VQSSDSDLFVIDPNTGVITTQGFL--------DFETKQSYHLTVKAFN 3272
DSG +AY + + S LF ID TG+ + + + D E S + +
Sbjct: 205 DSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEVEILSAVNFSADKEVMNSLEMFLPLLR 264
Query: 3273 VPDEERCSFATVNIQLKGTNEYVPRFVSK--LYYFEISEAAPKGTIVGEVFASDRDLGTD 3330
+ + + + + RF + L+Y ++ + A D
Sbjct: 265 HFKKVERDEEAAEKKFEASRGWFMRFKGRRHLHYLKVQDEAASA---------------D 309
Query: 3331 GEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVT 3390
GE N K + G IY++ L + +SL V A++ G + +VT
Sbjct: 310 GEAAARYVANLAKILGE-----GIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVT 364
Query: 3391 VNV---TVLDAN-DPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGS 3446
+++ T+ A + P +T +Y + E PIGT V A + + S Y I S
Sbjct: 365 IHIFQTTLAPAEFERPKYTFLVYE-DVPEDSPIGT----VKA--REPLNSSEPIFYRISS 417
Query: 3447 GNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDN 3506
G+ G FSI+P+ G I LD ET P+ L+V A G+ A S + +T+ D+NDN
Sbjct: 418 GDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQA-QLGSAPACSSTEVNITVMDVNDN 476
Query: 3507 GP--MLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTA- 3563
P + T E + + PGT + ++ D D N G Y + S P F++ A
Sbjct: 477 HPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRN-GLIRYSIAS--PQPGVFAIDRAL 533
Query: 3564 GVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPS 3612
GVL + + + L++ +D GV ++ + + + + +PS
Sbjct: 534 GVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPS 582
Score = 84.7 bits (208), Expect = 2e-15
Identities = 59/179 (32%), Positives = 87/179 (48%), Gaps = 29/179 (16%)
Query: 2060 PENTPIDTVVFKAQ-------------ATDPDSGPNSYIEYTLLNPL-----GNKFSIGT 2101
PE +VF++Q A+D DSG +IEY+L + F I
Sbjct: 54 PETELWGAIVFRSQEENAKPVKETEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDP 113
Query: 2102 IDGEVRLTGELDRE-EVSNYTLTVVATDKGQP----------SLSSSTEVVVMVLDINDN 2150
DG++ ++ ++DRE + + Y L V A D + LS+ V V + D+NDN
Sbjct: 114 HDGQICVSQDIDRERDPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDN 173
Query: 2151 NPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTG 2209
+P+F + Y I++ T GT+II V A D D G G V Y ++ GN + F IDS TG
Sbjct: 174 HPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTG 232
>gi|13325064 cadherin EGF LAG seven-pass G-type receptor 2 [Homo
sapiens]
Length = 2923
Score = 598 bits (1543), Expect = e-170
Identities = 518/1819 (28%), Positives = 804/1819 (44%), Gaps = 195/1819 (10%)
Query: 2750 SPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISR 2808
SP +S + N+ + AP+F + A VPEN P G V + D D G
Sbjct: 162 SPEESLGGRRKRNV----NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLE 217
Query: 2809 YSIMDASLP------FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVT 2859
Y+ MDA F+++P TG + + L+RE + RV+A D G + +T
Sbjct: 218 YT-MDALFDSRSNQFFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLT 276
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIK-----SQ 2914
I VTD ND+ P F + Y E E+G +V V ATD D N + Y + S
Sbjct: 277 ILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSP 336
Query: 2915 SEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETT--VTIN 2972
SE F I+ +G I + + + V + V +SD+G+ TT V ++
Sbjct: 337 SEVFEIDPRSGVIRTRGPVDREEVESYQ--------LTVEASDQGRDPGPRSTTAAVFLS 388
Query: 2973 IVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKF 3032
+ D NDNAPQF + +Y V ++V G ++RVTA D+D G N+ V Y I + N G+F
Sbjct: 389 VEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTA-SDRDKGSNAVVHYSIMSGNARGQF 447
Query: 3033 KLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSS-QATVHITVTEENYHTPEFSQ 3091
LD TG + V S L + + + + V A+D G PPLS+ V + V + N + P F
Sbjct: 448 YLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVS 507
Query: 3092 SHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKA 3151
+ AT+ ES +G +V V A D DA N ++Y ++ + F IN+ TG +++A
Sbjct: 508 TPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAE 567
Query: 3152 LDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGT 3211
LD E + + A D G A T SV+V V+DVNDN+P F +Y + E+A GT
Sbjct: 568 LDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGT 627
Query: 3212 TVIHLNATDADSGTNAVIAYTVQSSDS-DLFVIDPNT--GVITTQGFLDFETKQSYHLTV 3268
+V+ ++A D D+ ++VI Y + S ++ + F I + G+++ LD++ ++ Y L V
Sbjct: 628 SVVTVSAVDRDA--HSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAV 685
Query: 3269 KAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG 3328
A D R A + + + N + P F S Y ++E P GT V + A+D D G
Sbjct: 686 TA---SDGTRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTG 742
Query: 3329 TDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDE 3388
+ + Y F F+I+ TG + LD E + +L + A++ G + + D
Sbjct: 743 ENARITY--FMEDSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKS--DT 798
Query: 3389 VTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSG 3447
+ + V D ND P F + Y + E VP T V +SA D DS + F F G
Sbjct: 799 TYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGD 858
Query: 3448 NENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNG 3507
+ +G F + +G + LDRE + Y L AVD G P A + VT+ D+NDN
Sbjct: 859 DGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNP 918
Query: 3508 PMLTVSEGEVM--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AG 3564
P+ E +V EN G V + +TDPD N Y + G F L +G
Sbjct: 919 PVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQ--IMYQIVEGNIPEVFQLDIFSG 976
Query: 3565 VLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYY 3624
L+ ++D E ++ L V + + P + S TVH+ ++D+NDNP EI N Y
Sbjct: 977 ELTALVDLDYEDRPEYVL--VIQATSAP-LVSRATVHVRLLDRNDNPPVLGNFEILFNNY 1033
Query: 3625 ----GNLFPGGILGSVKPQDPDVLDSFHCSLTSG-VTSLFSIPGGTCDLNSQPRSTDGTF 3679
+ FPGG +G V DPD+ DS S G SL + T +L R+ D
Sbjct: 1034 VTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNASTGELKLS-RALDNNR 1092
Query: 3680 DL----TVLSNDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNHYLHFLR 3735
L +VL +DGVHS VT+ + ++ + +SI LRL + + FL+ F++
Sbjct: 1093 PLEAIMSVLVSDGVHS-VTAQCALRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQ 1151
Query: 3736 IASSQLTGLGTAVQLYSAYEENNRT-FLLAAVKRNHNQYVNPSGVATFFES--------- 3785
++ L V +++ + + + V + Q P G F S
Sbjct: 1152 AVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPPGPGGGPPFLPSEDLQERLYL 1211
Query: 3786 IKEILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQP 3845
+ +L S +V D + C+ PC+N C+ L S S V+ P+
Sbjct: 1212 NRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAPFIASSSVLFRPIHPVGG 1271
Query: 3846 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDI--NE 3903
C+C PG+ G +CE ++D C PC G C + GG++C C DG+TG CE
Sbjct: 1272 LRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGR 1331
Query: 3904 CLQSPCKNGAICQN-FPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYC 3962
C CKNG C N G F C
Sbjct: 1332 CTPGVCKNGGTCVNLLVGGFKC-------------------------------------- 1353
Query: 3963 HCPFGVFGK-HCELNSYGFEELSYMEFPSLDPNNNY-IYVKFATIKSHALLLYNYDNQTG 4020
CP G F K +C++ + F S++ F L ++ + + FAT + LLLYN +
Sbjct: 1354 DCPSGDFEKPYCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYN--GRFN 1411
Query: 4021 DRAEFLALEIAEERLRFSYNLGSGTYKLTTMKK--VSDGHFHTV--------IARRAGM- 4069
++ +F+ALE+ +E+++ +++ G T ++ VSDG +HTV + + G+
Sbjct: 1412 EKHDFVALEVIQEQVQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLP 1471
Query: 4070 -------AASLTVDSCSENQEPGY--------CTVSNVAVSDDWTLDVQPNRVTVGGIRS 4114
A +TVD C + C +LD+ + +GG+
Sbjct: 1472 QGPSEQKVAVVTVDGCDTGVALRFGSVLGNYSCAAQGTQGGSKKSLDL-TGPLLLGGV-- 1528
Query: 4115 LEPILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALAAQGILDQCPRLEGACTRSPCQHG 4174
P L V FVGC+ V+ R ++ + +A G + CP + C + C +G
Sbjct: 1529 --PDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCHNG 1586
Query: 4175 GTCMDYWSWQQCHCKEGLTGKYC-EKSVTPDTALSLEGKGRLDYHMSQNEKREYLLRQSL 4233
GTC++ W C C G GK C ++ P L G + +H L
Sbjct: 1587 GTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFL---GSSLVAWH-------------GL 1630
Query: 4234 RGAMLEPFGVNSLEVKFRTRSENGVLIH-IQESSNYTTVKIKNGKVYFTSDAGIAGKVER 4292
+ +P+ L + FRTR +GVL+ I + T++++ G V + +
Sbjct: 1631 SLPISQPW---YLSLMFRTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSL 1687
Query: 4293 NIPEVYVADGHWH--TFLIGKNGTA--TVLSVDRIYNRDIIHPTQDFGGLDVLTISLGGI 4348
+ DG WH +G +G +LS D R + GL + I++GGI
Sbjct: 1688 RLEPGRANDGDWHHAQLALGASGGPGHAILSFDYGQQRAEGNLGPRLHGLHLSNITVGGI 1747
Query: 4349 PPNQAHRDAQTAGFDGCIASMWYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNP 4408
P GF GC+ + G +SL +V+ GC P+ C SNP
Sbjct: 1748 P---GPAGGVARGFRGCLQGVRVSDTP---EGVNSLDPSHGESINVEQGCSLPDPCDSNP 1801
Query: 4409 CWGDLLCINQWYAYRC-VPPG--------DCASHPCQNGGSC--EPGLHSGFTCSCPDSH 4457
C + C N W +Y C PG C +PC++ C +P G+TC CP ++
Sbjct: 1802 CPANSYCSNDWDSYSCSCDPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNY 1861
Query: 4458 TGRTCEMVVACLGVLCPQG 4476
G CE + CP+G
Sbjct: 1862 LGPYCE---TRIDQPCPRG 1877
Score = 465 bits (1197), Expect = e-130
Identities = 325/916 (35%), Positives = 470/916 (51%), Gaps = 53/916 (5%)
Query: 584 QPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRS---FRLDPVSGR 640
QP Y +V EN P GT + LRA D D G+ G + +++ +A D RS F LDPV+G
Sbjct: 182 QPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTM-DALFDSRSNQFFSLDPVTGA 240
Query: 641 LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKE 700
++T LDRE ++ + V A D G P +S++A + + + D ND+ PVF +Y ++E
Sbjct: 241 VTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRE 300
Query: 701 NEPGGSYITTVSATDPDLGTNGTVKYSI---SAGDRSR-FQVNAQSGVISTRMALDREEK 756
N G + TV ATD D N + Y + S G S F+++ +SGVI TR +DREE
Sbjct: 301 NLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPVDREEV 360
Query: 757 TAYQLQIVATDGGNLQSPNQ--AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGS 814
+YQL + A+D G P A V ++V D DN P FS+ Y V E+V G V
Sbjct: 361 ESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLR 420
Query: 815 VSASTMDLNSN--ISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG- 871
V+AS D SN + Y I +G+ +G F ++ TG L + +D E Y L+V A G
Sbjct: 421 VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGG 480
Query: 872 -----TVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNG 926
V+G +V + V D+NDN+P F+ V+E+ G+ + +A+D D G N
Sbjct: 481 RPPLSNVSG--LVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNA 538
Query: 927 MVLYSLKQNPKNL-FAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTV 984
+ Y L + F IN G IS+ LD Y + A D G P L++S ++V
Sbjct: 539 RLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSV 598
Query: 985 YVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAF 1044
V DVNDN+P F Q Y V L+E V + V A D+D A+ I Y I GNT + F
Sbjct: 599 TVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD--AHSVITYQITSGNTRNRF 656
Query: 1045 GIFPD---GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFN 1101
I G + + LD +L+ +YVL V ASD + T + V + D N +RP+F
Sbjct: 657 SITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQD---TAQIVVNVTDANTHRPVFQ 713
Query: 1102 STNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQF 1161
S++YT E++ AG+ V +SA D+D G N + Y E P F + A +G +T +
Sbjct: 714 SSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAEL 773
Query: 1162 DRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISE 1221
D E + ++ + A D GIPQ D + + + D+NDNAP+FL+D YQ ++ E
Sbjct: 774 DYEDQVS------YTLAITARDNGIPQK-SDTTYLEILVNDVNDNAPQFLRDSYQGSVYE 826
Query: 1222 SAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE-ERQFAIDSTSGQVTLIGKLDYEATPA 1280
T VL++SA+D D G NG + Y+ G++ + F ++STSG V + +LD E
Sbjct: 827 DVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQ 886
Query: 1281 YSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTAT 1340
Y L AVD G P + + + +LD NDN P F + V V EN IG V+ VTAT
Sbjct: 887 YVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTAT 946
Query: 1341 DSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPR 1400
D D G NA + Y I N F + +G + LD+E + Y L I A P
Sbjct: 947 DPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATS---APL 1003
Query: 1401 SSTMSVVIHVRDFNDNPPSFPPGDI-FKSIVEN----IPIGTSVISVTAHDPDADINGQL 1455
S +V + + D NDNPP +I F + V N P G ++ V AHDP DI+ L
Sbjct: 1004 VSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFP-GGAIGRVPAHDP--DISDSL 1060
Query: 1456 SYTIIQQMPRGNHFTI 1471
+Y+ RGN ++
Sbjct: 1061 TYS----FERGNELSL 1072
Score = 428 bits (1100), Expect = e-119
Identities = 328/1019 (32%), Positives = 492/1019 (48%), Gaps = 57/1019 (5%)
Query: 358 FPATSRYASVDENAQVGTVVALLTVTDADSPAANG-NISVQILGGNEQRHFEVQSSKVPN 416
F S A+V EN GT VA L D D A ++ L + F S P
Sbjct: 181 FQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQF---FSLDPV 237
Query: 417 LSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFS 476
+ A LDRE ++ V+ D +G P RS++A+L I V D NDH PVF
Sbjct: 238 TGAVTTAEELDRETKSTHVFRVTAQD-HGMP------RRSALATLTILVTDTNDHDPVFE 290
Query: 477 QQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNG---LGWFHISEHSGLVT 533
QQ Y+ +L E G V + ATDGD+ NAN+ Y ++ G+G F I SG++
Sbjct: 291 QQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIR 350
Query: 534 TGSSGGLDRELASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVS 591
T G +DRE L + A DQG P+ + A + +++ D ND P FS+ + Y V
Sbjct: 351 T--RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSE-KRYVVQ 407
Query: 592 VVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREE 651
V E+ G +L + A+D D G N V +S+ R F LD +G L +S LD E
Sbjct: 408 VREDVTPGAPVLRVTASDRDKGSNAVVHYSIMSGNA-RGQFYLDAQTGALDVVSPLDYET 466
Query: 652 QAFYSLLVLATDLGSPPQSSMA-RINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT 710
Y+L V A D G PP S+++ + V +LDINDN+P+F + A + E+ P G +
Sbjct: 467 TKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLH 526
Query: 711 VSATDPDLGTNGTVKYSIS-AGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
V A D D G N ++Y ++ G F +N +G IS LDREE Y + A D G
Sbjct: 527 VQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHG 586
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYL 829
A V++TVLD DN P F+Q Y+ + E+ A+G V +VSA D +S I+Y
Sbjct: 587 TPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQ 646
Query: 830 ITTGDQKGMFAINQVT--GQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLN 887
IT+G+ + F+I + G ++ A +D + + Y L V AS GT + + V D N
Sbjct: 647 ITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDAN 706
Query: 888 DNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNG 947
+ P F + +VNV E+ AG ++ A D D G N + Y ++ + F I+ G
Sbjct: 707 THRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQ-FRIDADTG 765
Query: 948 TISLLGPLDVH-AGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLS 1006
++ LD SY + I A D G+PQ S + L + V+DVNDN+P F + SY+ ++
Sbjct: 766 AVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVY 825
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKS--ELDRELQD 1064
E P + ++ A+D+DSG NG + YT G+ GD I +++ LDRE
Sbjct: 826 EDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVA 885
Query: 1065 RYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSA 1124
+YVL A D+ + P + VTV + DVNDN P+F + + EE G V +V+A
Sbjct: 886 QYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTA 945
Query: 1125 VDKDFGPNGEVRYSF--EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIAT 1182
D D G N ++ Y + F+L SGE+T D E +
Sbjct: 946 TDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPE----------YVLV 995
Query: 1183 DQGIPQPLKDQATVHVYMKDINDNAP-----KFLKDFYQATISESAANLTQVLRVSASDV 1237
Q PL +ATVHV + D NDN P + L + Y S S + RV A D
Sbjct: 996 IQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPG-GAIGRVPAHDP 1054
Query: 1238 DEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNS 1297
D ++ + YS +GNE +++++G++ L LD P +++ V G + +
Sbjct: 1055 DISDS--LTYSFERGNELSLVLLNASTGELKLSRALD-NNRPLEAIMSVLVSDGVHSVTA 1111
Query: 1298 TCTLNIDILDENDNTPSFPKSTLFVDVLENMR-----IGELVSSVTATDSDSGDNADLY 1351
C L + I+ + T S TL ++ + R +G + +V AT + D+ ++
Sbjct: 1112 QCALRVTIITDEMLTHSI---TLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVVVF 1167
Score = 425 bits (1093), Expect = e-118
Identities = 324/999 (32%), Positives = 499/999 (49%), Gaps = 55/999 (5%)
Query: 1942 PIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI-ASGDSLGQ--FTVDK-N 1997
P F SY ++ EN P G+ V D D+G +L Y++ A DS F++D
Sbjct: 179 PQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVT 238
Query: 1998 GVLKVLKALDRESQS--FYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPK 2055
G + + LDRE++S + + Q H +P R ++ A ++I++ D ND+ P F +
Sbjct: 239 GAVTTAEELDRETKSTHVFRVTAQDHGMP-----RRSALATLTILVTDTNDHDPVFEQQE 293
Query: 2056 LTY-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK----FSIGTIDGEVRLTG 2110
+ EN + V +ATD D+ PN+ I Y LL G F I G +R G
Sbjct: 294 YKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRG 353
Query: 2111 ELDREEVSNYTLTVVATDKGQ-PSLSSSTEVVVM-VLDINDNNPIFAQALYKVEINENTL 2168
+DREEV +Y LTV A+D+G+ P S+T V + V D NDN P F++ Y V++ E+
Sbjct: 354 PVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVT 413
Query: 2169 TGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLT 2228
G +++V A+D D+G+N V Y I++GN +F +D+ TGA+ V PLD E T Y L
Sbjct: 414 PGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLR 473
Query: 2229 VQATDRGSTPRTDTS-TVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDD 2287
V+A D G P ++ S V++ +LDIND P+F +P+ V E++ L +L V A D
Sbjct: 474 VRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESV-PLGYLVLHVQAIDA 532
Query: 2288 DRGSNSKLSYVLFGGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITATDSGSPALTG 2346
D G N++L Y L G D FT++ +G + V LDRE + + + A D G+PALT
Sbjct: 533 DAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTA 592
Query: 2347 TGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN- 2405
+ +++V V DVNDN PTF Y + EDA GT V+ V+A D DA +I GN
Sbjct: 593 SASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNT 652
Query: 2406 -SQFTI-NPSTGQIITSAL-LDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
++F+I + S G +++ AL LD + + Y L V SD + + ++V VTD N +
Sbjct: 653 RNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQD----TAQIVVNVTDANTH 708
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAI 2522
P FQ Y ++ G+ V ++ TD D G N+ + Y + + +F ID GA+
Sbjct: 709 RPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMED-SIPQFRIDADTGAV 767
Query: 2523 MAAGPLNGASEV--TFSVHVKDGGSFPKTDST--TVTVRFVNKADFPKVRAKEQTFMFPE 2578
L+ +V T ++ +D G K+D+T + V VN +R Q ++ +
Sbjct: 768 TTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYED 827
Query: 2579 NQPVSSLV---TTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKY 2635
P +S++ T S L G + + F ++ +G V + LD E + +Y
Sbjct: 828 VPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQY 887
Query: 2636 VVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTVSAM 2693
V+ A D G PP + ++ +TVLDVNDN P+F++D F + EN SP + V+A
Sbjct: 888 VLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEEN-SPIGLAVARVTAT 946
Query: 2694 DKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQ 2753
D D G N Q+ Y+IV GN+ F ++ +GE+ ++ LD E YVL I+++ S+
Sbjct: 947 DPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSR 1006
Query: 2754 STSVKVMINILDENDNAP---RFSQIFSAHVPENSPL--GYTVTRVTTSDEDIGINAISR 2808
+T V + +LD NDN P F +F+ +V S G + RV D DI +
Sbjct: 1007 AT---VHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYS 1063
Query: 2809 YSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDN 2868
+ + +N STG++ +SR L+ + V D +V+ + VT I D
Sbjct: 1064 FERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDE 1123
Query: 2869 APRFSRTSYYLD-------CPELTEIGSKVTQVFATDPD 2900
S T D P L V AT PD
Sbjct: 1124 MLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPD 1162
Score = 408 bits (1049), Expect = e-113
Identities = 312/967 (32%), Positives = 476/967 (49%), Gaps = 56/967 (5%)
Query: 1418 PSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTI--IQQMPRGNHFTIDEVK 1475
P F P ++ EN P GT V S+ A DPD G+L YT+ + F++D V
Sbjct: 179 PQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVT 238
Query: 1476 GTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNAL 1535
G + T E+DRE + V A D +P RR AL +TILVTD ND+ P+F Q
Sbjct: 239 GAVTTAEELDRETKSTHVFRVTAQDHGMP---RRSALATLTILVTDTNDHDPVFEQQEYK 295
Query: 1536 AA-DPSAVIGSVLTTIMAADPDEGANGEIEYEIINGD----TDTFIVDRYSGDLRVASAL 1590
+ + +G + T+ A D D N I Y ++ G ++ F +D SG +R +
Sbjct: 296 ESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPV 355
Query: 1591 VPSQL-IYNLIVSATDLGPERRKSTTELTIILQGLD----GPVFTQPKYITILKEGEPIG 1645
++ Y L V A+D G + +T + L D P F++ +Y+ ++E G
Sbjct: 356 DREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG 415
Query: 1646 TNVISIEAAS-PRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACL 1704
V+ + A+ +GS A V Y I+S + F + TG + + LD E
Sbjct: 416 APVLRVTASDRDKGSNAVVHYSIMSGNARGQ-----FYLDAQTGALDVVSPLDYETTK-E 469
Query: 1705 YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTA 1764
Y + V A + V + + DINDN P+F + TV E++ G ++ + A
Sbjct: 470 YTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQA 529
Query: 1765 MDADEGANALVTYTIIS-GADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDG---L 1820
+DAD G NA + Y + G D F I+ +G + LDRE YS V A D
Sbjct: 530 IDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPA 589
Query: 1821 QSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIV 1880
++ +++TV DVND+ P F++P Y+ + ED G+ V + A D D+ + ITY +
Sbjct: 590 LTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVITYQI 647
Query: 1881 NEDDEDGIFFLNPITG--VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVN 1938
+ F + +G + +L LDY++++ Y+L V A DG Q T ++ N+ D N
Sbjct: 648 TSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQ-DTAQIVVNVTDAN 706
Query: 1939 DNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKN- 1997
+ P+F + Y+ ++ E+ P G+TV++ + TD D G N+++TY + DS+ QF +D +
Sbjct: 707 THRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME--DSIPQFRIDADT 764
Query: 1998 GVLKVLKALDRESQSFYNLVVQVHD--LPQIPASRFTSTAQVSIILLDVNDNPPTFLSPK 2055
G + LD E Q Y L + D +PQ + T + I++ DVNDN P FL
Sbjct: 765 GAVTTQAELDYEDQVSYTLAITARDNGIPQK-----SDTTYLEILVNDVNDNAPQFLRDS 819
Query: 2056 LT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLL--NPLGNKFSIGTIDGEVRLTGEL 2112
+ E+ P T V + ATD DSG N + YT + F + + G VR L
Sbjct: 820 YQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRL 879
Query: 2113 DREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTD 2172
DRE V+ Y L A DKG P + EV V VLD+NDN P+F Q + V + EN+ G
Sbjct: 880 DRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLA 939
Query: 2173 IIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQAT 2232
+ +V A D DEGTN Q+ Y IV GN + F++D +G +T LD E P Y L +QAT
Sbjct: 940 VARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQAT 999
Query: 2233 DRGSTPRTDTSTVSIVLLDINDFVPV---FELSPYSVNVPENLGTLP-RTILQVVARDDD 2288
S P +TV + LLD ND PV FE+ ++ V + P I +V A D D
Sbjct: 1000 ---SAPLVSRATVHVRLLDRNDNPPVLGNFEIL-FNNYVTNRSSSFPGGAIGRVPAHDPD 1055
Query: 2289 RGSNSKLSYVLFGGNEDNAFTLSAS-GELGVTQSLDRETKERFVLMITATDSGSPALTGT 2347
+ L+Y GNE + L+AS GEL ++++LD ++ + +D G ++T
Sbjct: 1056 --ISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSD-GVHSVTAQ 1112
Query: 2348 GTINVIV 2354
+ V +
Sbjct: 1113 CALRVTI 1119
Score = 399 bits (1026), Expect = e-110
Identities = 313/996 (31%), Positives = 492/996 (49%), Gaps = 75/996 (7%)
Query: 51 VLEEQPPGTLVGTIQT---RPGFTYRL---------SESHALFAINSSTGALYTTSTIDR 98
V E QP GT V +++ G RL S S+ F+++ TGA+ T +DR
Sbjct: 190 VPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDPVTGAVTTAEELDR 249
Query: 99 ESLPSDVINLVVLSSAPTYPTEVR---VLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVI 155
E+ + V + + + +LV D ND+ PVF + +E+ G +V+
Sbjct: 250 ETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKESLRENLEVGYEVL 309
Query: 156 LDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQ 215
ATD D N + YR++ G+ + SG + ++G +DRE
Sbjct: 310 TVRATDGDAPPNA--NILYRLLEGSGGSPSEVFEIDPRSGV-----IRTRGPVDREEVES 362
Query: 216 YQLLVEVEDKGEP--KRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVA 273
YQL VE D+G R V ++V+D NDN P F Y V ED G+ VL+V
Sbjct: 363 YQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVT 422
Query: 274 AADADEGTNADIRYRLQDEGT--PFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVP 331
A+D D+G+NA + Y + F +D +TG + V PLD+E ++Y+L V+A D G P
Sbjct: 423 ASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRP 482
Query: 332 SLTGRAEAL-IQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
L+ + + +Q+LD+NDN P+ F +T A+V E+ +G +V + DAD+
Sbjct: 483 PLSNVSGLVTVQVLDINDNAPI-----FVSTPFQATVLESVPLGYLVLHVQAIDADA-GD 536
Query: 391 NGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGA 450
N + ++ G F + + I VA+ LDRE + Y+ V D +G P
Sbjct: 537 NARLEYRLAGVGHDFPFTINN----GTGWISVAAELDREEVDFYSFGVEARD-HGTP--- 588
Query: 451 AVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANL 510
A ++ AS+ + V D+ND+ P F+Q Y V L+E+A G+ V +SA D D+ ++ +
Sbjct: 589 ---ALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVI 643
Query: 511 RYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVV 570
Y I SGN F I+ SG + LD +L Q VL ++A D + AQ+VV
Sbjct: 644 TYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASD---GTRQDTAQIVV 700
Query: 571 TLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR 630
+ D N +PVF Q Y V+V E+ P GT ++++ ATD D G+N + + ++++
Sbjct: 701 NVTDANTHRPVF-QSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIP--- 756
Query: 631 SFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFY 690
FR+D +G ++T + LD E+Q Y+L + A D G P +S + + + D+NDN+P F
Sbjct: 757 QFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFL 816
Query: 691 PVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGD--RSRFQVNAQSGVISTR 748
Y + E+ P + + +SATD D G NG V Y+ GD F V + SG++ T
Sbjct: 817 RDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTL 876
Query: 749 MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVAL 808
LDRE Y L+ A D G + VT+TVLD DNPPVF Q + V EN +
Sbjct: 877 RRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPI 936
Query: 809 GYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKV 866
G V V+A+ D N+ I Y I G+ +F ++ +G+LT +D E++ Y L +
Sbjct: 937 GLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVI 996
Query: 867 VASGGTVTGDTMVNITVKDLNDNSPHFLQAIESV--NVVENWQA---GHSIFQAKAVDPD 921
A+ + V++ + D NDN P L E + N V N + G +I + A DPD
Sbjct: 997 QATSAPLVSRATVHVRLLDRNDNPP-VLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPD 1055
Query: 922 EGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLDVHAGSYQI-EILASDMGVPQLSSS 979
++ + YS ++ N +L +N G + L LD + I +L SD GV +++
Sbjct: 1056 --ISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSD-GVHSVTAQ 1112
Query: 980 VILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRF 1015
L V + + D + L++ +TL + RF
Sbjct: 1113 CALRVTI--ITD-----EMLTHSITLRLEDMSPERF 1141
Score = 390 bits (1003), Expect = e-107
Identities = 280/932 (30%), Positives = 447/932 (47%), Gaps = 51/932 (5%)
Query: 2359 DNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII-------GGNSQFTIN 2411
+ P F +Y T+PE+ P GT V + A D D + + N F+++
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLD 235
Query: 2412 PSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPY 2471
P TG + T+ LDRETK + V D G P S+ ++ + VTD ND+ P F+ Y
Sbjct: 236 PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPR-RSALATLTILVTDTNDHDPVFEQQEY 294
Query: 2472 VTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL----SGRNSEKFHIDPLRGAIMAAGP 2527
+ G V V TD D PN+ + Y L G SE F IDP G I GP
Sbjct: 295 KESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGP 354
Query: 2528 LNGASEVTF--SVHVKDGGSFPKTDSTTVTVRFVNKAD----FPKVRAKEQTFMFPENQP 2581
++ ++ +V D G P STT V F++ D P+ K E+
Sbjct: 355 VDREEVESYQLTVEASDQGRDPGPRSTTAAV-FLSVEDDNDNAPQFSEKRYVVQVREDVT 413
Query: 2582 VSSLVTTITGSSL---RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVW 2638
+ V +T S + Y I SGN F +D TG + + PLD+E ++Y +
Sbjct: 414 PGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLR 473
Query: 2639 IEARDGGFPPFSSYEKL-DITVLDVNDNAPIFKEDPFISEILENLS-PRKILTVSAMDKD 2696
+ A+DGG PP S+ L + VLD+NDNAPIF PF + +LE++ +L V A+D D
Sbjct: 474 VRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDAD 533
Query: 2697 SGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTS 2756
+G N +L+Y + + F+IN+ TG I LDRE+V Y +++ D G+P+ + S
Sbjct: 534 AGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTAS 593
Query: 2757 VKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDAS 2815
V + +LD NDN P F+Q ++ + E++ +G +V V+ D D +++ Y I +
Sbjct: 594 ASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD--AHSVITYQITSGN 651
Query: 2816 L--PFTINPSTGD--IVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPR 2871
F+I +G + ++ PL+ + +Y + V+A D + + + VTD N + P
Sbjct: 652 TRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPV 711
Query: 2872 FSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQ 2931
F + Y ++ E G+ V + ATD D G N ++ YF++ FRI+A TG + +
Sbjct: 712 FQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQA 771
Query: 2932 ILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTP 2991
L Y++ + + +T+ D G P T + I + D NDNAPQFL+ Y
Sbjct: 772 ELDYEDQVSY--------TLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGS 823
Query: 2992 VTKNVKVGTKLIRVTAIDDKDFGLNSEVEY-FISNDNHLGKFKLDNDTGWISVASSLISD 3050
V ++V T +++++A D+D GLN V Y F D+ G F +++ +G + L +
Sbjct: 824 VYEDVPPFTSVLQISA-TDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRE 882
Query: 3051 LNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRT 3110
+ + A DKG PP + V +TV + N + P F Q + E+ IG V
Sbjct: 883 NVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVAR 942
Query: 3111 VSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGG 3170
V+A D D N I Y I GN +F ++ +G LT LDYE ++ + I A
Sbjct: 943 VTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAP 1002
Query: 3171 WVARTGYCSVTVNVIDVNDNSPV-----FLSDDYFPTVLENAPSGTTVIHLNATDADSGT 3225
V+R +V V ++D NDN PV L ++Y + P G + + A D D
Sbjct: 1003 LVSR---ATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGG-AIGRVPAHDPDISD 1058
Query: 3226 NAVIAYTVQSSDSDLFVIDPNTGVITTQGFLD 3257
+ ++ + ++ L +++ +TG + LD
Sbjct: 1059 SLTYSFE-RGNELSLVLLNASTGELKLSRALD 1089
Score = 375 bits (964), Expect = e-103
Identities = 307/1040 (29%), Positives = 483/1040 (46%), Gaps = 68/1040 (6%)
Query: 888 DNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK----QNPKNLFAIN 943
+ +P F V EN AG + +A+DPDEG G + Y++ F+++
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLD 235
Query: 944 EKNGTISLLGPLDVHAGSYQI-EILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE 1002
G ++ LD S + + A D G+P+ S+ LT+ V D ND+ PVF+Q Y+
Sbjct: 236 PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYK 295
Query: 1003 VTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP----DGQLYIKSEL 1058
+L E+ V V+A+D D+ N I Y + EG+ G +F G + + +
Sbjct: 296 ESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRTRGPV 355
Query: 1059 DRELQDRYVLMVVASDRAVEP--LSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAG 1116
DRE + Y L V ASD+ +P S T V + +ED NDN P F+ Y E+ G
Sbjct: 356 DREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG 415
Query: 1117 SFVGKVSAVDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFDRESLMRRRGTAV 1174
+ V +V+A D+D G N V YS + F L A +G + D E+ T
Sbjct: 416 APVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYET------TKE 469
Query: 1175 FSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSA 1234
++ V A D G P V V + DINDNAP F+ +QAT+ ES VL V A
Sbjct: 470 YTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQA 529
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
D D G+N + Y + + F I++ +G +++ +LD E YS ++A D GT
Sbjct: 530 IDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPA 589
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
L ++ ++++ +LD NDN P+F + V + E+ +G V +V+A D D+ ++ + Y I
Sbjct: 590 LTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVITYQI 647
Query: 1355 TGTNNHGTFSISPNTGS--IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
T N FSI+ +G + LA LD++ + Y L +TA D R T +V++V D
Sbjct: 648 TSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASD---GTRQDTAQIVVNVTD 704
Query: 1413 FNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTID 1472
N + P F ++ E+ P GT+V+ ++A D D N +++Y + +P+ F ID
Sbjct: 705 ANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQ---FRID 761
Query: 1473 EVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI-- 1530
G + T AE+D E + L + A D +P ++ L+ ILV D+NDN P F+
Sbjct: 762 ADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLE---ILVNDVNDNAPQFLRD 818
Query: 1531 SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGD--TDTFIVDRYSGDLRVAS 1588
S + SVL I A D D G NG + Y GD FIV+ SG +R
Sbjct: 819 SYQGSVYEDVPPFTSVL-QISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLR 877
Query: 1589 ALVPSQLI-YNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
L + Y L A D G ++ E+T+ + ++ PVF Q ++ ++E PIG
Sbjct: 878 RLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIG 937
Query: 1646 TNVISIEAASP-RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACL 1704
V + A P G+ A + Y IV E + +F + +G + LD E
Sbjct: 938 LAVARVTATDPDEGTNAQIMYQIV-----EGNIPEVFQLDIFSGELTALVDLDYEDRP-- 990
Query: 1705 YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML----DLTVEENIGDGSKIM 1760
+ + ++T+ P RA V + L D NDNPPV + +T + G I
Sbjct: 991 ---EYVLVIQATSAPLVSRATVHVRLLDRNDNPPVLGNFEILFNNYVTNRSSSFPGGAIG 1047
Query: 1761 QLTAMDADEGANALVTYTIISGADDSF-RIDPESGDLIATRRLDRERRSKYSLLVRADDG 1819
++ A D D + +TY+ G + S ++ +G+L +R LD R + + V DG
Sbjct: 1048 RVPAHDPD--ISDSLTYSFERGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDG 1105
Query: 1820 LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSL-------VAAILATDDDSGV 1872
+ S + + V+ + D S + D+ + L VAA LAT D V
Sbjct: 1106 VHSVTAQCALRVTIITDEMLTHSITLRLEDMSPERFLSPLLGLFIQAVAATLATPPDHVV 1165
Query: 1873 NGEITYIVNEDDEDGIFFLN 1892
+ + + D G LN
Sbjct: 1166 ---VFNVQRDTDAPGGHILN 1182
Score = 347 bits (889), Expect = 2e-94
Identities = 300/997 (30%), Positives = 453/997 (45%), Gaps = 81/997 (8%)
Query: 130 DNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDI 189
+ AP F PS T E+ +G V A D D G G + + + + +F
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSNQF---F 232
Query: 190 TLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPV 249
+L+P GA + + LDRE + V +D G P+R + + V D ND+ PV
Sbjct: 233 SLDPV-TGA---VTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPV 288
Query: 250 FGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD--EGTP---FQMDPETGL 304
F Y+ + E+ VG VL V A D D NA+I YRL + G+P F++DP +G+
Sbjct: 289 FEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGV 348
Query: 305 ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRY 364
I R P+D E Y LTV+A D+G A + L +DND +F + RY
Sbjct: 349 IRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQF----SEKRY 404
Query: 365 -ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
V E+ G V +T +D D +N + I+ GN + F + + + V
Sbjct: 405 VVQVREDVTPGAPVLRVTASDRDK-GSNAVVHYSIMSGNARGQFYLDA----QTGALDVV 459
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLV-IFVNDINDHPPVFSQQVYRV 482
S LD E Y L V D G PP S+V+ LV + V DIND+ P+F ++
Sbjct: 460 SPLDYETTKEYTLRVRAQDG-GRPP------LSNVSGLVTVQVLDINDNAPIFVSTPFQA 512
Query: 483 NLSEEAPPGSYVSGISATDGDSGLNANLRYSIVS---------GNGLGWFHISEHSGLVT 533
+ E P G V + A D D+G NA L Y + NG GW ++
Sbjct: 513 TVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAE----- 567
Query: 534 TGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVV 593
LDRE + ARD G + A + VT+LDVND P F+QPE Y V +
Sbjct: 568 ------LDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPE-YTVRLN 620
Query: 594 ENAPTGTELLMLRATDGDLGDNGTVRFSLQEAET-DRRSFRLDPVSGRLSTISSLDREEQ 652
E+A GT ++ + A D D + + + + T +R S G +S LD + +
Sbjct: 621 EDAAVGTSVVTVSAVDRDA--HSVITYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLE 678
Query: 653 AFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVS 712
Y L V A+D + A+I V++ D N + PVF Y ++ E+ P G+ + +S
Sbjct: 679 RQYVLAVTASD---GTRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLIS 735
Query: 713 ATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQ 772
ATD D G N + Y + +F+++A +G ++T+ LD E++ +Y L I A D G Q
Sbjct: 736 ATDEDTGENARITYFME-DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQ 794
Query: 773 SPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLI 830
+ + I V D DN P F + +Y V+E+V V +SA+ D LN + Y
Sbjct: 795 KSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTF 854
Query: 831 TTGDQ-KGMFAINQVTGQLTTANVIDREEQSFYQLKVVA-SGGTVTGDT--MVNITVKDL 886
GD G F + +G + T +DRE + Y L+ A G T V +TV D+
Sbjct: 855 QGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDV 914
Query: 887 NDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEK 945
NDN P F Q V V EN G ++ + A DPDEG N ++Y + + N +F ++
Sbjct: 915 NDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIF 974
Query: 946 NGTISLLGPLDVH-AGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL----- 999
+G ++ L LD Y + I A+ L S + V + D NDN PV
Sbjct: 975 SGELTALVDLDYEDRPEYVLVIQATS---APLVSRATVHVRLLDRNDNPPVLGNFEILFN 1031
Query: 1000 SYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI-FPDGQLYIKSEL 1058
+Y S S P +V A D D + + Y+ GN + G+L + L
Sbjct: 1032 NYVTNRSSSFP-GGAIGRVPAHDPD--ISDSLTYSFERGNELSLVLLNASTGELKLSRAL 1088
Query: 1059 DRELQDRYVLMVVASDRAVEPLSA--TVNVTVILEDV 1093
D ++ V+ SD V ++A + VT+I +++
Sbjct: 1089 DNNRPLEAIMSVLVSD-GVHSVTAQCALRVTIITDEM 1124
Score = 57.8 bits (138), Expect = 3e-07
Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 19/117 (16%)
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGS-- 3921
D C +PC + C N +SCSC G+ G C N C +PC++ ++C P +
Sbjct: 1795 DPCDSNPCPANSYCSNDWDSYSCSCDPGYYGDNC---TNVCDLNPCEHQSVCTRKPSAPH 1851
Query: 3922 -FNCVCKTGYTGKMCESSVN---------YCECNPC----FNGGSCQSGVDSYYCHC 3964
+ C C Y G CE+ ++ + C PC G S CHC
Sbjct: 1852 GYTCECPPNYLGPYCETRIDQPCPRGWWGHPTCGPCNCDVSKGFDPDCNKTSGECHC 1908
Score = 53.5 bits (127), Expect = 5e-06
Identities = 43/147 (29%), Positives = 56/147 (38%), Gaps = 23/147 (15%)
Query: 3837 IVANEPLQP--FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTG 3894
+ +P P + C+C P Y G +CE ID+ PC G H G +C GF
Sbjct: 1842 VCTRKPSAPHGYTCECPPNYLGPYCETRIDQ----PCPRGWWGHPTCGPCNCDVSKGF-D 1896
Query: 3895 RACERDINECLQSPCKNGAICQNFPGSFNCVC----KTGYTGKMCESSVNYCECNPCFNG 3950
C + EC CK PGS C+ TG ++C+ C C P G
Sbjct: 1897 PDCNKTSGEC---HCKENH--YRPPGSPTCLLCDCYPTGSLSRVCDPEDGQCPCKPGVIG 1951
Query: 3951 GSCQSGVDSYYCHCPFG-VFGKHCELN 3976
C C PF V CE+N
Sbjct: 1952 RQCDR------CDNPFAEVTTNGCEVN 1972
Score = 53.1 bits (126), Expect = 7e-06
Identities = 41/159 (25%), Positives = 57/159 (35%), Gaps = 28/159 (17%)
Query: 3846 FLCKCLPGYAGSWCEIDIDECLPSPCHSGGTC---HNLVGGFSCSCPDGFTGRACERDIN 3902
+ C C PGY G C + C +PC C + G++C CP + G CE I+
Sbjct: 1815 YSCSCDPGYYGDNC---TNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYLGPYCETRID 1871
Query: 3903 ECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECN---------------PC 3947
+ PC G G NC G+ C + C C C
Sbjct: 1872 Q----PCPRGWWGHPTCGPCNCDVSKGFDPD-CNKTSGECHCKENHYRPPGSPTCLLCDC 1926
Query: 3948 FNGGSCQSGVD--SYYCHCPFGVFGKHCELNSYGFEELS 3984
+ GS D C C GV G+ C+ F E++
Sbjct: 1927 YPTGSLSRVCDPEDGQCPCKPGVIGRQCDRCDNPFAEVT 1965
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 598 bits (1543), Expect = e-170
Identities = 514/1809 (28%), Positives = 811/1809 (44%), Gaps = 204/1809 (11%)
Query: 2771 PRFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM----DASLP-FTINPST 2824
P+F Q + VPEN G V RV D D G YS+ SL F+I+P +
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 2825 GDIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRFSRTSYYLDC 2881
G I + L+RE +R+ +RV+A D G + +T V + V D ND++P F + Y
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETL 442
Query: 2882 PELTEIGSKVTQVFATDPDEGSNGQVFY-FI------KSQSEYFRINATTGEIFNKQILK 2934
E E G + Q+ ATD D N + Y F+ + + F I+ +G I +
Sbjct: 443 RENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVD 502
Query: 2935 YQNVTGFSNVNINRHSFIVTSSDRGK-PSLISETT-VTINIVDSNDNAPQFLKSKYFTPV 2992
+++ + +V +SD+G+ P S T V I ++D NDNAPQF + +Y V
Sbjct: 503 REHMESYE--------LVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQV 554
Query: 2993 TKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLN 3052
++V+ T ++RVTA D +D N V Y I + N G F +D+ TG I V + L +
Sbjct: 555 REDVRPHTVVLRVTATD-RDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAE 613
Query: 3053 QNFFITVTAKDKGNPPLSSQATV-HITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
+ + + + A+D G PPLS+ + I V + N H P F + ++ E+ +G V +
Sbjct: 614 REYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHI 673
Query: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
A D D N ++YS++ + F INS+TG ++++ LD E + + + A D G
Sbjct: 674 QAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGS 733
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAY 3231
+ SVTV V+DVNDN P F +Y + E+A GT+V+ + A D D+ N+ I+Y
Sbjct: 734 PPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--NSAISY 791
Query: 3232 TVQSSDS-DLFVIDPNTGV--ITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
+ ++ + F I GV +T LD++ ++ + L + A + + C V+I +
Sbjct: 792 QITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRALHDHC---YVHINI 848
Query: 3289 KGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI 3348
N + P F S Y ++E P G+ + + ASD D+G + + YL+ N + F+I
Sbjct: 849 TDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQ--FRI 906
Query: 3349 NKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLN 3407
+ +G I + LD E + +L + A++ G + A D V V V D ND P F +
Sbjct: 907 DADSGAITLQAPLDYEDQVTYTLAITARDNGIPQKA--DTTYVEVMVNDVNDNAPQFVAS 964
Query: 3408 IYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNE-NGAFSINPQTGQITVTA 3466
Y+ +SE P T V +SA D D+ + R Y +G + +G F+I P +G +
Sbjct: 965 HYTGLVSEDAPPFTSVLQISATDRDAHAN-GRVQYTFQNGEDGDGDFTIEPTSGIVRTVR 1023
Query: 3467 ELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPG 3524
LDRE + +Y L+ AVD G P S+ V ++D+NDN P+ E E V EN G
Sbjct: 1024 RLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVG 1083
Query: 3525 TLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLS 3583
++V + + DPD PN Y + G F + +G L+ ++D E ++
Sbjct: 1084 SVVAQITAVDPDEGPN--AHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYV-- 1139
Query: 3584 VVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYY----GNLFPGGILGSVKPQ 3639
+V + + P + S TVH+ ++DQNDN +I N Y + FP GI+G +
Sbjct: 1140 IVVQATSAP-LVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAY 1198
Query: 3640 DPDVLDSFHCSLTSGVTSLFSIPGGTCDLNSQPRSTDGTFDLT----VLSNDGVHSTVTS 3695
DPDV D S G + T R D L V DG+HS VT+
Sbjct: 1199 DPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHS-VTA 1257
Query: 3696 NIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYE 3755
+ + + NS+ +RL + FL+ FL ++ L V +++
Sbjct: 1258 QCVLRVVIITEELLANSLTVRLENMWQERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQN 1317
Query: 3756 ENN--RTFLLAAVKRNHNQYVNPSGVATFFES---IKEILLRQSGVKVESV------DHD 3804
+ + T L + + +F S +++ +R++ + S+ D +
Sbjct: 1318 DTDVGGTVLNVSFSALAPRGAGAGAAGPWFSSEELQEQLYVRRAALAARSLLDVLPFDDN 1377
Query: 3805 SCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVAN---EPLQPFL---CKCLPGYAGSW 3858
C+ PC+N C+ SVL+ S P + A+ P+QP C+C PG+ G +
Sbjct: 1378 VCLREPCENYMKCV------SVLRFDSSAPFLASASTLFRPIQPIAGLRCRCPPGFTGDF 1431
Query: 3859 CEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERD--INECLQSPCKNGAICQ 3916
CE ++D C +PC +GG C GG++C C FTG CE D C+ C+NG C
Sbjct: 1432 CETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDCELDTEAGRCVPGVCRNGGTCT 1491
Query: 3917 NFP-GSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVF-GKHCE 3974
+ P G F C C G G F G CE
Sbjct: 1492 DAPNGGFRCQCPAG-------------------------------------GAFEGPRCE 1514
Query: 3975 LNSYGFEELSYMEFPSLDPNNNY-IYVKFATIKSHALLLYNYDNQTGDRAEFLALEIAEE 4033
+ + F S++ F L + + + FAT++ LL YN + ++ +FLALE+
Sbjct: 1515 VAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYN--GRLNEKHDFLALELVAG 1572
Query: 4034 RLRFSYNLGSGTYKL--TTMKKVSDGHFHTVIAR----------------RAGMAASLTV 4075
++R +Y+ G + T +SDG +HTV R A L+V
Sbjct: 1573 QVRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPSKDKVAVLSV 1632
Query: 4076 DSCSE------NQEPG--YCTVSNVAVSDDWTLDVQPNRVTVGGIRSLEPILQRRGHVES 4127
D C E G C + V S +LD+ + +GG+ P L V
Sbjct: 1633 DDCDVAVALQFGAEIGNYSCAAAGVQTSSKKSLDL-TGPLLLGGV----PNLPENFPVSH 1687
Query: 4128 HDFVGCIMEFAVNGRPLEPSQALAAQGILDQCPRLEGACTRSPCQHGGTCMDYWSWQQCH 4187
DF+GC+ + ++GR ++ + +A G + C C PC++ G C + W C
Sbjct: 1688 KDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQAKLHFCDSGPCKNSGFCSERWGSFSCD 1747
Query: 4188 CKEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQNEKREYLLRQSLRGAMLEPFGVNSLE 4247
C G GK C+ +T G G L ++ + A+ P+ L
Sbjct: 1748 CPVGFGGKDCQ--LTMAHPHHFRGNGTLSWNFGSDM------------AVSVPW---YLG 1790
Query: 4248 VKFRTRSENGVLIHIQESSNYTTV-KIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHT 4306
+ FRTR+ GVL+ +Q + T + ++ G + T G + +V V+DG WH
Sbjct: 1791 LAFRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHD 1850
Query: 4307 FLI-------GKNG-TATVLSVDRIYNRDIIHPTQDFGGLDVLTISLGGIPPNQAHRDAQ 4358
+ G+ G ++S+D +D + + GL V + +GG+PP A Q
Sbjct: 1851 LRLELQEEPGGRRGHHVLMVSLDFSLFQDTMAVGSELQGLKVKQLHVGGLPPGSAEEAPQ 1910
Query: 4359 TAGFDGCIASMWYGGESLPFSGKHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQ 4418
G GCI +W G S P SG +L S + + GC N CAS PC C +
Sbjct: 1911 --GLVGCIQGVWLG--STP-SGSPALLPPSHR-VNAEPGCVVTNACASGPCPPHADCRDL 1964
Query: 4419 WYAYRCV-PPG--------DCASHPCQNGGSCE--PGLHSGFTCSCPDSHTGRTCEMVVA 4467
W + C PG C +PCQN GSC PG G+TC C + G CE
Sbjct: 1965 WQTFSCTCQPGYYGPGCVDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCE---H 2021
Query: 4468 CLGVLCPQG 4476
+ CP+G
Sbjct: 2022 RMDQQCPRG 2030
Score = 443 bits (1139), Expect = e-123
Identities = 321/952 (33%), Positives = 472/952 (49%), Gaps = 55/952 (5%)
Query: 580 PVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDR--RSFRLDPV 637
P F Q Y V EN GT +L + A D D G+ G + +SL R F +DP
Sbjct: 323 PQFPQ-YNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQ 381
Query: 638 SGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAH 697
SG + T ++LDRE + L V A D GSP S+ + V++ D ND+SPVF QY
Sbjct: 382 SGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRET 441
Query: 698 IKENEPGGSYITTVSATDPDLGTNGTVKY------SISAGDRSRFQVNAQSGVISTRMAL 751
++EN G I + ATD D N ++Y + A + F+++ +SG+IST +
Sbjct: 442 LRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRV 501
Query: 752 DREEKTAYQLQIVATDGGNLQSPNQAIVT--ITVLDTQDNPPVFSQVAYSFVVFENVALG 809
DRE +Y+L + A+D G P A V ITVLD DN P FS+ Y V E+V
Sbjct: 502 DREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPH 561
Query: 810 YHVGSVSASTMDLNSN--ISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVV 867
V V+A+ D ++N + Y I +G+ +G FAI+ +TG++ +D E + Y L++
Sbjct: 562 TVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIR 621
Query: 868 ASGG---TVTGDT-MVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEG 923
A ++ +T + +I V D+ND+ P F+ V+V+EN GHS+ +AVD D G
Sbjct: 622 AQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHG 681
Query: 924 VNGMVLYSLK-QNPKNLFAINEKNGTISLLGPLDVHA-GSYQIEILASDMGVPQLSSSVI 981
N + YSL P F IN G +S+ GPLD + Y + A D G P LS+S
Sbjct: 682 ENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASAS 741
Query: 982 LTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTG 1041
+TV V DVNDN P F Y + L+E V + V A D+D AN I+Y I GNT
Sbjct: 742 VTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRD--ANSAISYQITGGNTR 799
Query: 1042 DAFGIFPDGQLYIKS---ELDRELQDRYVLMVVASDRAV-EPLSATVNVTVILEDVNDNR 1097
+ F I G + + + LD + + + L++ ASDRA+ + +N+T D N +R
Sbjct: 800 NRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRALHDHCYVHINIT----DANTHR 855
Query: 1098 PLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITN 1157
P+F S +Y+ E++ GS + +SA D D G N + Y E P F + A SG IT
Sbjct: 856 PVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITL 915
Query: 1158 THQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQA 1217
D E ++ + A D GIPQ D V V + D+NDNAP+F+ Y
Sbjct: 916 QAPLDYED------QVTYTLAITARDNGIPQK-ADTTYVEVMVNDVNDNAPQFVASHYTG 968
Query: 1218 TISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE-ERQFAIDSTSGQVTLIGKLDYE 1276
+SE A T VL++SA+D D NG + Y+ G + + F I+ TSG V + +LD E
Sbjct: 969 LVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDRE 1028
Query: 1277 ATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSS 1336
A Y L AVD G PL + ++ + + D NDN P FP V V EN +G +V+
Sbjct: 1029 AVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQ 1088
Query: 1337 VTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQG 1396
+TA D D G NA + Y I N F + +G + LD+E + Y + + A
Sbjct: 1089 ITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATS-- 1146
Query: 1397 RPPRSSTMSVVIHVRDFNDNPPSFPPGDI-FKSIVEN----IPIGTSVISVTAHDPDADI 1451
P S +V + + D NDN P I F + V N P G + + A+DP D+
Sbjct: 1147 -APLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGI-IGRIPAYDP--DV 1202
Query: 1452 NGQLSYTIIQQMPRGNH---FTIDEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ L Y+ RGN +++ G + + ++D + + V D
Sbjct: 1203 SDHLFYS----FERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTD 1250
Score = 414 bits (1064), Expect = e-114
Identities = 295/926 (31%), Positives = 473/926 (51%), Gaps = 46/926 (4%)
Query: 1942 PIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIAS---GDSLGQFTVD-KN 1997
P F +Y T + EN G+ VL D D G +L YS+A+ SL F++D ++
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 1998 GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT 2057
G+++ ALDRES + L V D + R ++T V++ + D ND+ P F +
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHG---SPRLSATTMVAVTVADRNDHSPVFEQAQYR 439
Query: 2058 Y-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK------FSIGTIDGEVRLTG 2110
+ EN + + +ATD D+ PN+ + Y + P + F I G + +G
Sbjct: 440 ETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSG 499
Query: 2111 ELDREEVSNYTLTVVATDKGQPS--LSSSTEVVVMVLDINDNNPIFAQALYKVEINENTL 2168
+DRE + +Y L V A+D+GQ S++ V + VLD NDN P F++ Y ++ E+
Sbjct: 500 RVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVR 559
Query: 2169 TGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLT 2228
T +++V A D D+ NG V Y I++GN+ F IDS+TG I V PLD E Y L
Sbjct: 560 PHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALR 619
Query: 2229 VQATDRGSTPRTD-TSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDD 2287
++A D G P ++ T SI ++DIND +P+F +P+ V+V EN L +++ + A D
Sbjct: 620 IRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLEN-APLGHSVIHIQAVDA 678
Query: 2288 DRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGSPALTG 2346
D G N++L Y L G D F + SA+G + V+ LDRE+ E + + A D GSP L+
Sbjct: 679 DHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSA 738
Query: 2347 TGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN- 2405
+ ++ V V DVNDN P F K Y + EDA GT V+ V A D DA+ +I GGN
Sbjct: 739 SASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNT 798
Query: 2406 -SQFTINPSTG-QIITSAL-LDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
++F I+ G ++T AL LD + + + LV+ SD L V + +TD N +
Sbjct: 799 RNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASD----RALHDHCYVHINITDANTH 854
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAI 2522
P FQ Y + GS + ++ +D D+G N+ + Y L N +F ID GAI
Sbjct: 855 RPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLED-NLPQFRIDADSGAI 913
Query: 2523 MAAGPLNGASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPEN 2579
PL+ +VT+++ + +D G K D+T V V + D P+ A T + E+
Sbjct: 914 TLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSED 973
Query: 2580 QPVSSLVTTITGSSLRGEP---MSYYIASGNLGN-TFQIDQLTGQVSISQPLDFEKIQKY 2635
P + V I+ + + Y +G G+ F I+ +G V + LD E + Y
Sbjct: 974 APPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVY 1033
Query: 2636 VVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILEN-LSPRKILTVSAMD 2694
+ A D G PP + + + V DVNDNAP+F + F + EN + + ++A+D
Sbjct: 1034 ELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVD 1093
Query: 2695 KDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQS 2754
D GPN + Y+IV GN+ F ++ +GE+ ++ LD E YV+ ++++ S++
Sbjct: 1094 PDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSRA 1153
Query: 2755 TSVKVMINILDENDNAP---RFSQIFSAHVPENS---PLGYTVTRVTTSDEDIGINAISR 2808
T V + ++D+NDN+P F +F+ +V S P G + R+ D D+ +
Sbjct: 1154 T---VHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSG-IIGRIPAYDPDVSDHLFYS 1209
Query: 2809 YSIMDASLPFTINPSTGDIVISRPLN 2834
+ + +N ++G++ +SR L+
Sbjct: 1210 FERGNELQLLVVNQTSGELRLSRKLD 1235
Score = 365 bits (938), Expect = e-100
Identities = 283/939 (30%), Positives = 453/939 (48%), Gaps = 70/939 (7%)
Query: 75 SESHALFAINSSTGALYTTSTIDRESLPSDVINLVVL---SSAPTYPTEVRVLVRDLNDN 131
S S LF+I+ +G + T + +DRES+ + + S + T V V V D ND+
Sbjct: 370 SRSLELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDH 429
Query: 132 APVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRII-----RGNEAGRFR 186
+PVF T +E+ G ++ ATD D N + YR + R A F
Sbjct: 430 SPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNA--NLRYRFVGPPAARAAAAAAFE 487
Query: 187 LDITLNPSGEGAFLHLVSKGG-LDREVTPQYQLLVEVEDKGEP--KRRGYLQVNVTVQDI 243
+D SG L+S G +DRE Y+L+VE D+G+ R ++V++TV D
Sbjct: 488 ID---PRSG------LISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDE 538
Query: 244 NDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGT--PFQMDPE 301
NDN P F Y A V ED + VL+V A D D+ N + Y + + F +D
Sbjct: 539 NDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSL 598
Query: 302 TGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAE-ALIQLLDVNDNDPVVKFRYFPA 360
TG I V PLDFEA R+Y+L ++A D G P L+ A IQ++D+ND+ P+ F +
Sbjct: 599 TGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPI-----FVS 653
Query: 361 TSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLI 420
T SV ENA +G V + DAD N + + G F + S+ +
Sbjct: 654 TPFQVSVLENAPLGHSVIHIQAVDADH-GENARLEYSLTGVAPDTPFVINSA----TGWV 708
Query: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
V+ LDRE + Y V D +G+PP S+ AS+ + V D+ND+ P F+ + Y
Sbjct: 709 SVSGPLDRESVEHYFFGVEARD-HGSPP------LSASASVTVTVLDVNDNRPEFTMKEY 761
Query: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGL 540
+ L+E+A G+ V ++A D D+ N+ + Y I GN F IS G+ + L
Sbjct: 762 HLRLNEDAAVGTSVVSVTAVDRDA--NSAISYQITGGNTRNRFAISTQGGVGLVTLALPL 819
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
D + L ++A D+ +H + + + + D N +PVF Q Y VSV E+ P G+
Sbjct: 820 DYKQERYFKLVLTASDRALH---DHCYVHINITDANTHRPVF-QSAHYSVSVNEDRPMGS 875
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL 660
++++ A+D D+G+N + + L E + FR+D SG ++ + LD E+Q Y+L +
Sbjct: 876 TIVVISASDDDVGENARITYLL---EDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAIT 932
Query: 661 ATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGT 720
A D G P ++ + V + D+NDN+P F Y + E+ P + + +SATD D
Sbjct: 933 ARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHA 992
Query: 721 NGTVKYSISAGD--RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAI 778
NG V+Y+ G+ F + SG++ T LDRE + Y+L A D G
Sbjct: 993 NGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVS 1052
Query: 779 VTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQK 836
+ + V D DN PVF + V EN +G V ++A D N++I Y I G+
Sbjct: 1053 IQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIP 1112
Query: 837 GMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQA 896
+F ++ +G+LT +D E + Y + V A+ + V++ + D NDNSP
Sbjct: 1113 ELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSRATVHVRLVDQNDNSP----V 1168
Query: 897 IESVNVV-ENWQAGHS-------IFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ + ++ N+ + S I + A DPD V+ + YS ++ N L +N+ +G
Sbjct: 1169 LNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPD--VSDHLFYSFERGNELQLLVVNQTSG 1226
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYV 986
+ L LD + ++ G+ +++ +L V +
Sbjct: 1227 ELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVI 1265
Score = 363 bits (933), Expect = 2e-99
Identities = 299/968 (30%), Positives = 457/968 (47%), Gaps = 56/968 (5%)
Query: 1418 PSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH--FTIDEVK 1475
P FP + + EN GT+V+ V A DPDA G+L Y++ M + F+ID
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 1476 GTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI-SQNA 1534
G I T A +DRE L V A D P R A V + V D ND+ P+F +Q
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHGSP---RLSATTMVAVTVADRNDHSPVFEQAQYR 439
Query: 1535 LAADPSAVIGSVLTTIMAADPDEGANGEIEYEIIN------GDTDTFIVDRYSGDLRVAS 1588
+ G + + A D D N + Y + F +D SG + +
Sbjct: 440 ETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSG 499
Query: 1589 ALVPSQL-IYNLIVSATDLG--PERRKSTTE--LTIILQGLDGPVFTQPKYITILKEGEP 1643
+ + Y L+V A+D G P R +T +T++ + + P F++ +Y+ ++E
Sbjct: 500 RVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVR 559
Query: 1644 IGTNVISIEAAS-PRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGA 1702
T V+ + A + + V Y I+S F I TG IQ A LD E
Sbjct: 560 PHTVVLRVTATDRDKDANGLVHYNIISGNSRGH-----FAIDSLTGEIQVVAPLDFEAER 614
Query: 1703 CLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQL 1762
Y + + A + I + DIND+ P+F + ++V EN G ++ +
Sbjct: 615 -EYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHI 673
Query: 1763 TAMDADEGANALVTYTIISGADDS-FRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQ 1821
A+DAD G NA + Y++ A D+ F I+ +G + + LDRE Y V A D
Sbjct: 674 QAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGS 733
Query: 1822 ---SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITY 1878
S+ + +TV DVND+ P+F+ Y + ED G+ V ++ A D D+ N I+Y
Sbjct: 734 PPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--NSAISY 791
Query: 1879 IVNEDDEDGIFFLNPITGV--FNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILD 1936
+ + F ++ GV L LDY+ ++Y+ L + A D V+ NI D
Sbjct: 792 QITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA-LHDHCYVHINITD 850
Query: 1937 VNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDK 1996
N + P+F YS S+ E+ P+GST++V + +D D G N+++TY + D+L QF +D
Sbjct: 851 ANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLE--DNLPQFRIDA 908
Query: 1997 N-GVLKVLKALDRESQSFYNLVVQVHD--LPQIPASRFTSTAQVSIILLDVNDNPPTFLS 2053
+ G + + LD E Q Y L + D +PQ T V +++ DVNDN P F++
Sbjct: 909 DSGAITLQAPLDYEDQVTYTLAITARDNGIPQK-----ADTTYVEVMVNDVNDNAPQFVA 963
Query: 2054 PKLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--FSIGTIDGEVRLTG 2110
T + E+ P T V + ATD D+ N ++YT N F+I G VR
Sbjct: 964 SHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVR 1023
Query: 2111 ELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTG 2170
LDRE VS Y LT A D+G P L + + VMV D+NDN P+F ++V + EN++ G
Sbjct: 1024 RLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVG 1083
Query: 2171 TDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQ 2230
+ + Q+ A D DEG N + Y IV GN + F++D +G +T LD E Y + VQ
Sbjct: 1084 SVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQ 1143
Query: 2231 ATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVN--VPENLGTLPRTIL-QVVARDD 2287
AT S P +TV + L+D ND PV N V T P I+ ++ A D
Sbjct: 1144 AT---SAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDP 1200
Query: 2288 DRGSNSKLSYVLFGGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITATDSGSPALTG 2346
D + L Y GNE ++ SGEL +++ LD +++T TD G ++T
Sbjct: 1201 D--VSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTD-GLHSVTA 1257
Query: 2347 TGTINVIV 2354
+ V++
Sbjct: 1258 QCVLRVVI 1265
Score = 362 bits (928), Expect = 7e-99
Identities = 308/1047 (29%), Positives = 474/1047 (45%), Gaps = 76/1047 (7%)
Query: 1095 DNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFE--MVQPDFELHAI- 1151
+ P F NY E + AG+ V +V A D D G G + YS M EL +I
Sbjct: 320 NRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSID 379
Query: 1152 --SGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPK 1209
SG I DRES+ R V A D G P+ L V V + D ND++P
Sbjct: 380 PQSGLIRTAAALDRESMERH------YLRVTAQDHGSPR-LSATTMVAVTVADRNDHSPV 432
Query: 1210 FLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSII-----KGNEERQFAIDSTS 1264
F + Y+ T+ E+ +L++ A+D D N + Y + + F ID S
Sbjct: 433 FEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRS 492
Query: 1265 GQVTLIGKLDYEATPAYSLVIQAVDSGTI--PLNSTCTLNIDILDENDNTPSFPKSTLFV 1322
G ++ G++D E +Y LV++A D G P ++T ++I +LDENDN P F +
Sbjct: 493 GLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVA 552
Query: 1323 DVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFET 1382
V E++R +V VTATD D N ++Y+I N+ G F+I TG I + LDFE
Sbjct: 553 QVREDVRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEA 612
Query: 1383 QSLYKLNITAKDQGRPPRSSTMSVV-IHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVIS 1441
+ Y L I A+D GRPP S+ + I V D ND+ P F S++EN P+G SVI
Sbjct: 613 EREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIH 672
Query: 1442 VTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQ 1501
+ A D D N +L Y++ P F I+ G + + +DRE + V+A D
Sbjct: 673 IQAVDADHGENARLEYSLTGVAP-DTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDH 731
Query: 1502 AVPIETRRYALKNVTILVTDLNDNVPMF-ISQNALAADPSAVIGSVLTTIMAADPDEGAN 1560
P + A +VT+ V D+NDN P F + + L + A +G+ + ++ A D D AN
Sbjct: 732 GSPPLS---ASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRD--AN 786
Query: 1561 GEIEYEIINGDTDTFIVDRYSGDLRVASALVP----SQLIYNLIVSATDLGPERRKSTTE 1616
I Y+I G+T G + + + +P + + L+++A+D
Sbjct: 787 SAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRALHDH-CYVH 845
Query: 1617 LTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ I PVF Y + E P+G+ ++ I A+ E Y++ +
Sbjct: 846 INITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQ-- 903
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDN 1736
F I +G I A LD E Y + + A + + VE+ + D+NDN
Sbjct: 904 ----FRIDADSGAITLQAPLDYED-QVTYTLAITARDNGIP-QKADTTYVEVMVNDVNDN 957
Query: 1737 PPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG--ADDSFRIDPESG 1794
P F V E+ + ++Q++A D D AN V YT +G D F I+P SG
Sbjct: 958 APQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSG 1017
Query: 1795 DLIATRRLDRERRSKYSLLVRA-DDGLQ--SSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ RRLDRE S Y L A D G+ + + I + V DVND+ P F + +
Sbjct: 1018 IVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVK 1077
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQY 1911
E++I GS+VA I A D D G N I Y + E + +F ++ +G LDYE +Q
Sbjct: 1078 ENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQE 1137
Query: 1912 YILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFS-----LNSYSTSLMENLPVGSTVLVF 1966
Y++ V+A + V+ ++D NDN P+ + N+Y ++ + P G ++
Sbjct: 1138 YVIVVQA-TSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSG---IIG 1193
Query: 1967 NVTDADDGINSQLTYSIASGDSLGQFTVDK-NGVLKVLKALDRESQSFYNLVVQVHD-LP 2024
+ D ++ L YS G+ L V++ +G L++ + LD +++V V D L
Sbjct: 1194 RIPAYDPDVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLH 1253
Query: 2025 QIPASRFTSTAQVSIILLDVNDNPPT----------FLSPKLTYIPEN------TPI-DT 2067
+ A +V II ++ N T FLSP L E TP D
Sbjct: 1254 SVTAQ---CVLRVVIITEELLANSLTVRLENMWQERFLSPLLGRFLEGVAAVLATPAEDV 1310
Query: 2068 VVFKAQATDPDSGPNSYIEYTLLNPLG 2094
+F Q G + ++ L P G
Sbjct: 1311 FIFNIQNDTDVGGTVLNVSFSALAPRG 1337
Score = 359 bits (922), Expect = 3e-98
Identities = 284/962 (29%), Positives = 456/962 (47%), Gaps = 60/962 (6%)
Query: 891 PHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSL----KQNPKNLFAINEKN 946
P F Q V EN AG ++ + A DPD G G ++YSL LF+I+ ++
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSIDPQS 382
Query: 947 GTISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTL 1005
G I LD + + + + A D G P+LS++ ++ V V D ND+SPVF+Q Y TL
Sbjct: 383 GLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRETL 442
Query: 1006 SESEPVNSRFFKVQASDKDSGANGEIAYTI-----AEGNTGDAFGIFP-DGQLYIKSELD 1059
E+ +++A+D D+ N + Y A AF I P G + +D
Sbjct: 443 RENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTSGRVD 502
Query: 1060 RELQDRYVLMVVASDRAVEP--LSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGS 1117
RE + Y L+V ASD+ EP SATV V + + D NDN P F+ Y E+ R +
Sbjct: 503 REHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDVRPHT 562
Query: 1118 FVGKVSAVDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFDRESLMRRRGTAVF 1175
V +V+A D+D NG V Y+ + F + +++GEI D E+ +
Sbjct: 563 VVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAERE------Y 616
Query: 1176 SFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSAS 1235
+ + A D G P + + + DIND+ P F+ +Q ++ E+A V+ + A
Sbjct: 617 ALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAV 676
Query: 1236 DVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPL 1295
D D G N + YS+ + F I+S +G V++ G LD E+ Y ++A D G+ PL
Sbjct: 677 DADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPL 736
Query: 1296 NSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSIT 1355
+++ ++ + +LD NDN P F + + E+ +G V SVTA D D+ N+ + Y IT
Sbjct: 737 SASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--NSAISYQIT 794
Query: 1356 GTNNHGTFSISP--NTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDF 1413
G N F+IS G + LA LD++ + +KL +TA D+ V I++ D
Sbjct: 795 GGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDA 851
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDE 1473
N + P F S+ E+ P+G++++ ++A D D N +++Y + +P+ F ID
Sbjct: 852 NTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQ---FRIDA 908
Query: 1474 VKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQN 1533
G I A +D E + L + A D +P ++ V ++V D+NDN P F++ +
Sbjct: 909 DSGAITLQAPLDYEDQVTYTLAITARDNGIP---QKADTTYVEVMVNDVNDNAPQFVASH 965
Query: 1534 --ALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGD--TDTFIVDRYSGDLRVASA 1589
L ++ + SVL I A D D ANG ++Y NG+ F ++ SG +R
Sbjct: 966 YTGLVSEDAPPFTSVL-QISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRR 1024
Query: 1590 LVPSQL-IYNLIVSATDLGPERRKSTTELTIILQGL--DGPVFTQPKYITILKEGEPIGT 1646
L + +Y L A D G ++ + +++Q + + PVF ++ +KE +G+
Sbjct: 1025 LDREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGS 1084
Query: 1647 NVISIEAASP-RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLY 1705
V I A P G A + Y IV E + LF + +G + LD E
Sbjct: 1085 VVAQITAVDPDEGPNAHIMYQIV-----EGNIPELFQMDIFSGELTALIDLDYEARQ--- 1136
Query: 1706 LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPT-DMLDLTVEENIGD---GSKIMQ 1761
+ + ++T+ P RA V + L D NDN PV +L N D I +
Sbjct: 1137 --EYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGR 1194
Query: 1762 LTAMDADEGANALVTYTIISGAD-DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGL 1820
+ A D D + + Y+ G + ++ SG+L +R+LD R S+LV DGL
Sbjct: 1195 IPAYDPDVSDH--LFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGL 1252
Query: 1821 QS 1822
S
Sbjct: 1253 HS 1254
Score = 350 bits (897), Expect = 3e-95
Identities = 302/1004 (30%), Positives = 465/1004 (46%), Gaps = 71/1004 (7%)
Query: 122 RVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNG-VDHRSYRIIRGN 180
R R + P FP + E+ ++G V+ A D D G G + + ++
Sbjct: 312 RARFRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSR 371
Query: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
F +D SG + + LDRE ++ L V +D G P+ V VTV
Sbjct: 372 SLELFSID---PQSGL-----IRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTV 423
Query: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL-------QDEG 293
D ND+ PVF + Y+ + E+ G +LQ+ A D D NA++RYR
Sbjct: 424 ADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAA 483
Query: 294 TPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVP----SLTGRAEALIQLLDVNDN 349
F++DP +GLI+ +D E Y L V+A D+G S T R I +LD NDN
Sbjct: 484 AAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVH--ITVLDENDN 541
Query: 350 DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
P F A V E+ + TVV +T TD D ANG + I+ GN + HF +
Sbjct: 542 AP-----QFSEKRYVAQVREDVRPHTVVLRVTATDRDKD-ANGLVHYNIISGNSRGHFAI 595
Query: 410 QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIN 469
S I+V + LD E Y L + D G PP + + +AS I V DIN
Sbjct: 596 DSL----TGEIQVVAPLDFEAEREYALRIRAQD-AGRPP---LSNNTGLAS--IQVVDIN 645
Query: 470 DHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHS 529
DH P+F ++V++ E AP G V I A D D G NA L YS+ F I+ +
Sbjct: 646 DHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSAT 705
Query: 530 GLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYD 589
G V+ SG LDRE + ARD G P + A + VT+LDVND +P F+ E Y
Sbjct: 706 GWVSV--SGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKE-YH 762
Query: 590 VSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSG-RLSTIS-SL 647
+ + E+A GT ++ + A D D N + + + T R F + G L T++ L
Sbjct: 763 LRLNEDAAVGTSVVSVTAVDRDA--NSAISYQITGGNT-RNRFAISTQGGVGLVTLALPL 819
Query: 648 DREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSY 707
D +++ ++ L++ A+D +++++ D N + PVF Y + E+ P GS
Sbjct: 820 DYKQERYFKLVLTASDRA---LHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGST 876
Query: 708 ITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD 767
I +SA+D D+G N + Y + + +F+++A SG I+ + LD E++ Y L I A D
Sbjct: 877 IVVISASDDDVGENARITYLLE-DNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARD 935
Query: 768 GGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN-- 825
G Q + V + V D DN P F Y+ +V E+ V +SA+ D ++N
Sbjct: 936 NGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGR 995
Query: 826 ISYLITTG-DQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNI 881
+ Y G D G F I +G + T +DRE S Y+L A V + +
Sbjct: 996 VQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQV 1055
Query: 882 TVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLF 940
V+D+NDN+P F V V EN G + Q AVDPDEG N ++Y + + N LF
Sbjct: 1056 MVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPELF 1115
Query: 941 AINEKNGTISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL- 999
++ +G ++ L LD A + I+ P +S + + V + D NDNSPV +
Sbjct: 1116 QMDIFSGELTALIDLDYEARQEYV-IVVQATSAPLVSRATV-HVRLVDQNDNSPVLNNFQ 1173
Query: 1000 ----SYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI-FPDGQLYI 1054
+Y S++ P + ++ A D D + + Y+ GN + G+L +
Sbjct: 1174 ILFNNYVSNRSDTFP-SGIIGRIPAYDPD--VSDHLFYSFERGNELQLLVVNQTSGELRL 1230
Query: 1055 KSELDRELQDRYVLMVVASDRAVEPLSA--TVNVTVILEDVNDN 1096
+LD ++V +D + ++A + V +I E++ N
Sbjct: 1231 SRKLDNNRPLVASMLVTVTD-GLHSVTAQCVLRVVIITEELLAN 1273
Score = 350 bits (897), Expect = 3e-95
Identities = 287/974 (29%), Positives = 460/974 (47%), Gaps = 65/974 (6%)
Query: 2149 DNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRY---GIVNGNTNQEFRID 2205
+ +P F Q Y+ + EN GT +++V A D D G G++ Y ++N + + F ID
Sbjct: 320 NRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFSID 379
Query: 2206 SVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYS 2265
+G I A LDRE ++L V A D GS + T+ V++ + D ND PVFE + Y
Sbjct: 380 PQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYR 439
Query: 2266 VNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA------SGELGVT 2319
+ EN+ ILQ+ A D D N+ L Y G A +A SG + +
Sbjct: 440 ETLRENVEE-GYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLISTS 498
Query: 2320 QSLDRETKERFVLMITATDSGSP--ALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDA 2377
+DRE E + L++ A+D G + T +++ V D NDN P F+ K Y + ED
Sbjct: 499 GRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVREDV 558
Query: 2378 PTGTDVLLVNASDADASKNAVI--RIIGGNSQ--FTINPSTGQIITSALLDRETKDNYTL 2433
T VL V A+D D N ++ II GNS+ F I+ TG+I A LD E + Y L
Sbjct: 559 RPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYAL 618
Query: 2434 VVVCSDAGSPEPLSSSTSVL-VTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTD 2492
+ DAG P PLS++T + + V D+ND+ P F P+ + G V + D
Sbjct: 619 RIRAQDAGRP-PLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVD 677
Query: 2493 ADIGPNSELHYSLSG-RNSEKFHIDPLRGAIMAAGPLNGAS--EVTFSVHVKDGGSFPKT 2549
AD G N+ L YSL+G F I+ G + +GPL+ S F V +D GS P +
Sbjct: 678 ADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLS 737
Query: 2550 DSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSSLVTTITGSSL-RGEPMSYYIASGN 2607
S +VTV ++ D P+ KE E+ V + V ++T +SY I GN
Sbjct: 738 ASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGN 797
Query: 2608 LGNTFQIDQL--TGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDN 2665
N F I G V+++ PLD+++ + + + + A D + + I + D N +
Sbjct: 798 TRNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDANTH 854
Query: 2666 APIFKEDPFISEILENL-SPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGE 2724
P+F+ + + E+ I+ +SA D D G N ++ Y ++ N+ F I+ +G
Sbjct: 855 RPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITY-LLEDNLP-QFRIDADSGA 912
Query: 2725 IRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPE 2783
I PLD E Y L I + D G P ++ + V + + D NDNAP+F + ++ V E
Sbjct: 913 ITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSE 972
Query: 2784 NSPLGYTVTRVTTSDEDIGINAISRYSIM---DASLPFTINPSTGDIVISRPLNREDTDR 2840
++P +V +++ +D D N +Y+ D FTI P++G + R L+RE
Sbjct: 973 DAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSV 1032
Query: 2841 YRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFAT 2897
Y + A D G + + V D+NDNAP F + + E + +GS V Q+ A
Sbjct: 1033 YELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAV 1092
Query: 2898 DPDEGSNGQVFYFIKSQS--EYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTS 2955
DPDEG N + Y I + E F+++ +GE+ L Y+ R +++
Sbjct: 1093 DPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYE----------ARQEYVIVV 1142
Query: 2956 SDRGKPSLISETTVTINIVDSNDNAP-----QFLKSKYFTPVTKNVKVGTKLIRVTAIDD 3010
P L+S TV + +VD NDN+P Q L + Y + + G + R+ A D
Sbjct: 1143 QATSAP-LVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGI-IGRIPAYDP 1200
Query: 3011 KDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISD--LNQNFFITVTAKDKGNPP 3068
++ + Y N L ++ +G + ++ L ++ L + +TVT G
Sbjct: 1201 ---DVSDHLFYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVT---DGLHS 1254
Query: 3069 LSSQATVHITVTEE 3082
+++Q + + + E
Sbjct: 1255 VTAQCVLRVVIITE 1268
Score = 146 bits (368), Expect = 6e-34
Identities = 120/416 (28%), Positives = 191/416 (45%), Gaps = 39/416 (9%)
Query: 46 RQVFQ-------VLEEQPPGTLVGTIQTRPG-------FTYRLSESHALFAINSSTGALY 91
R VFQ V E++P G+ + I TY L ++ F I++ +GA+
Sbjct: 855 RPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAIT 914
Query: 92 TTSTIDRESLPSDVINLVVLSSA---PTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDS 148
+ +D E + + + + T V V+V D+NDNAP F ED+
Sbjct: 915 LQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDA 974
Query: 149 SSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGL 208
V+ +ATD D +NG Y G + D T+ P+ + V + L
Sbjct: 975 PPFTSVLQISATDRDAHANG--RVQYTFQNGEDGDG---DFTIEPT--SGIVRTVRR--L 1025
Query: 209 DREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSS 268
DRE Y+L D+G P R + + V VQD+NDN PVF + ++ V E+++VGS
Sbjct: 1026 DREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSV 1085
Query: 269 VLQVAAADADEGTNADIRYRLQDEGTP--FQMDPETGLITVREPLDFEARRQYSLTVQAM 326
V Q+ A D DEG NA I Y++ + P FQMD +G +T LD+EAR++Y + VQA
Sbjct: 1086 VAQITAVDPDEGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQAT 1145
Query: 327 DRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDAD 386
L RA ++L+D NDN PV+ + + Y S + ++ + D
Sbjct: 1146 S---APLVSRATVHVRLVDQNDNSPVLN-NFQILFNNYVSNRSDTFPSGIIGRIPAYD-- 1199
Query: 387 SPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSD 442
P + ++ GNE + V + ++++ LD R ++ V+V+D
Sbjct: 1200 -PDVSDHLFYSFERGNELQLLVVNQTS----GELRLSRKLDNNRPLVASMLVTVTD 1250
Score = 65.9 bits (159), Expect = 1e-09
Identities = 47/158 (29%), Positives = 67/158 (42%), Gaps = 22/158 (13%)
Query: 3844 QPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVG---GFSCSCPDGFTGRACERD 3900
Q F C C PGY G C +D CL +PC + G+C +L G G++C C G+ G CE
Sbjct: 1966 QTFSCTCQPGYYGPGC---VDACLLNPCQNQGSCRHLPGAPHGYTCDCVGGYFGHHCEHR 2022
Query: 3901 IN-ECLQ--------SPCKNGAICQNFPGSFN-----CVCKTGYTGKMCESSVNYCECNP 3946
++ +C + PC N + + F + N C CK + S C+C P
Sbjct: 2023 MDQQCPRGWWGSPTCGPC-NCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYP 2081
Query: 3947 CFNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGFEELS 3984
S S C C G G+ C F E++
Sbjct: 2082 -VGSTSRSCAPHSGQCPCRPGALGRQCNSCDSPFAEVT 2118
Score = 61.6 bits (148), Expect = 2e-08
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 19/115 (16%)
Query: 3866 CLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGS---F 3922
C PC C +L FSC+C G+ G C ++ CL +PC+N C++ PG+ +
Sbjct: 1950 CASGPCPPHADCRDLWQTFSCTCQPGYYGPGC---VDACLLNPCQNQGSCRHLPGAPHGY 2006
Query: 3923 NCVCKTGYTGKMCESSVN-YC--------ECNPC----FNGGSCQSGVDSYYCHC 3964
C C GY G CE ++ C C PC G + CHC
Sbjct: 2007 TCDCVGGYFGHHCEHRMDQQCPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHC 2061
Score = 47.4 bits (111), Expect = 4e-04
Identities = 45/171 (26%), Positives = 59/171 (34%), Gaps = 47/171 (27%)
Query: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
D+C+ PCQN GSC R L + + C C+ GY G CE +
Sbjct: 1983 DACLLNPCQNQGSC-RHLPGAP------------------HGYTCDCVGGYFGHHCEHRM 2023
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNF----P 3919
D+ P TC G +C GF C + +C C+ F
Sbjct: 2024 DQQCPRGWWGSPTC----GPCNCDVHKGFDPN-CNKTNGQC---------HCKEFHYRPR 2069
Query: 3920 GSFNCV----CKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPF 3966
GS +C+ G T + C C C P G C S C PF
Sbjct: 2070 GSDSCLPCDCYPVGSTSRSCAPHSGQCPCRPGALGRQCNS------CDSPF 2114
>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
sapiens]
Length = 3014
Score = 574 bits (1479), Expect = e-163
Identities = 492/1765 (27%), Positives = 786/1765 (44%), Gaps = 210/1765 (11%)
Query: 2818 FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDINDNAPRFSR 2874
F I+ +TG + L+RE + + +RV A D + +T +T+ V D ND++P F +
Sbjct: 296 FRIDSATGAVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQ 355
Query: 2875 TSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQS-EYFRINATTGEIFNKQIL 2933
+ Y E E+G +V + A+D D N + Y + + + F++N ++G + + +L
Sbjct: 356 SEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVL 415
Query: 2934 KYQNVTGFSNVNINRHSFIVTSSDRGK-PSLISET-TVTINIVDSNDNAPQFLKSKYFTP 2991
+ + +V ++D+G+ P +S T TV I + D NDN PQF + Y
Sbjct: 416 DREEAA--------EYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQ 467
Query: 2992 VTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDL 3051
V ++V + T ++RV A D +D G N+ + Y I + N G+F L + +G + V + L +
Sbjct: 468 VPEDVGLNTAVLRVQATD-RDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFED 526
Query: 3052 NQNFFITVTAKDKGNPPL-SSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRT 3110
Q + +++ A+D G PPL +S V + V + N + P F S AT+ E+ +G V
Sbjct: 527 VQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVH 586
Query: 3111 VSARDRDAAMNGLIKYSI-----------SSGNEEGI------FAINSSTGILTLAKALD 3153
+ A D D+ N + Y + S+G + F I++S+G +T+ LD
Sbjct: 587 IQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELD 646
Query: 3154 YELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTV 3213
E + + + A+D G + SV++ V+DVNDN PVF Y + E+A G++V
Sbjct: 647 REEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSV 706
Query: 3214 IHLNATDADSGTNAVIAYTVQSSDS-DLFVIDPNTG--VITTQGFLDFETKQSYHLTVKA 3270
+ L A D D+ N+VI Y + ++ + F + G +IT LD++ +Q Y L V A
Sbjct: 707 LTLQARDRDA--NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTA 764
Query: 3271 FNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTD 3330
D R A V I + N + P F S Y +SE P GT + + A+D D G +
Sbjct: 765 ---SDGTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGEN 821
Query: 3331 GEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVT 3390
+ Y+I F+I+ +G +Y LD E + +L ++A++ G + +D T
Sbjct: 822 ARITYVI--QDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDT--TT 877
Query: 3391 VNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNE 3449
+ + +LDAND P F + Y I E P T + VSA D DS P+ F G +
Sbjct: 878 LEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDG 937
Query: 3450 NGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA-TGSASLLVTLEDINDNGP 3508
+G F I P +G I LDRE + +YNL LAVD G+P+ + S + VT+ DINDN P
Sbjct: 938 DGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAP 997
Query: 3509 MLTVSEGE--VMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTA-GV 3565
M E E V EN G++V +++ DPD PN Y + G +F L G
Sbjct: 998 MFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQ--IMYQIVEGDMRHFFQLDLLNGD 1055
Query: 3566 LSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYY- 3624
L E+D E ++ L V + + P + S TVHI ++DQNDNP +I N Y
Sbjct: 1056 LRAMVELDFEVRREYVL--VVQATSAP-LVSRATVHILLVDQNDNPPVLPDFQILFNNYV 1112
Query: 3625 ---GNLFPGGILGSVKPQDPDVLDSFHCSLTSG-VTSLFSIPGGTCDLNSQPRSTDGTFD 3680
N FP G++G + DPDV DS + + G L + T +L R D
Sbjct: 1113 TNKSNSFPTGVIGCIPAHDPDVSDSLNYTFVQGNELRLLLLDPATGELQLS-RDLDNNRP 1171
Query: 3681 LTVLS----NDGVHSTVTSNIRVFFAGFSNATVDNSILLRLGVPTVKDFLTNHYLHFLRI 3736
L L +DG+HS VT+ + ++ + NSI +RL + + FL+ F+
Sbjct: 1172 LEALMEVSVSDGIHS-VTAFCTLRVTIITDDMLTNSITVRLENMSQEKFLSPLLALFVEG 1230
Query: 3737 ASSQLTGLGTAVQLYSAYEENNRTFLLAAVKRNHNQYVNPSGVATFF---ESIKE----- 3788
++ L+ V +++ N T + + + + P GV F E ++E
Sbjct: 1231 VAAVLSTTKDDVFVFNV---QNDTDVSSNILNVTFSALLPGGVRGQFFPSEDLQEQIYLN 1287
Query: 3789 --ILLRQSGVKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPF 3846
+L S +V D + C+ PC+N C+ L S S V+ P+
Sbjct: 1288 RTLLTTISTQRVLPFDDNICLREPCENYMKCVSVLRFDSSAPFLSSTTVLFRPIHPINGL 1347
Query: 3847 LCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDI--NEC 3904
C+C PG+ G +CE +ID C PC + G C + GG++C C + FTG CE D C
Sbjct: 1348 RCRCPPGFTGDYCETEIDLCYSDPCGANGRCRSREGGYTCECFEDFTGEHCEVDARSGRC 1407
Query: 3905 LQSPCKNGAICQN-FPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCH 3963
CKNG C N G F+CVC G +
Sbjct: 1408 ANGVCKNGGTCVNLLIGGFHCVCPPGEYER------------------------------ 1437
Query: 3964 CPFGVFGKHCELNSYGFEELSYMEFPSLDPNNNY-IYVKFATIKSHALLLYNYDNQTGDR 4022
+CE+ + F S++ F L ++ I + FAT + + LLLYN + ++
Sbjct: 1438 -------PYCEVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYN--GRFNEK 1488
Query: 4023 AEFLALEIAEERLRFSYNLGSGTYKLT--TMKKVSDGHFHTVIAR--------------- 4065
+F+ALEI +E+++ +++ G T + VSDG +H+V +
Sbjct: 1489 HDFIALEIVDEQVQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHG 1548
Query: 4066 -RAGMAASLTVDSCSENQEPGY--------CTVSNVAVSDDWTLDVQPNRVTVGGIRSLE 4116
A +TVD C + C +LD+ + +GG+
Sbjct: 1549 PSGEKMAVVTVDDCDTTMAVRFGKDIGNYSCAAQGTQTGSKKSLDL-TGPLLLGGV---- 1603
Query: 4117 PILQRRGHVESHDFVGCIMEFAVNGRPLEPSQALAAQGILDQCPRLEGACTRSPCQHGGT 4176
P L V + FVGC+ +V+G+ ++ + +A G + C C CQ+GGT
Sbjct: 1604 PNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRCQNGGT 1663
Query: 4177 CMDYWSWQQCHCKEGLTGKYCEKSVTPDTALSLEGKGRLDYHMSQNEKREYLLRQSLRGA 4236
C++ W+ C C GK CE+++ S E + L
Sbjct: 1664 CVNRWNMYLCECPLRFGGKNCEQAMPHPQLFSGE---------------SVVSWSDLNII 1708
Query: 4237 MLEPFGVNSLEVKFRTRSENGVLIHIQESSNYT-TVKIKNGKVYFTSDAGIAGKVERNIP 4295
+ P+ L + FRTR E+ VL+ + ++I N + F G + +
Sbjct: 1709 ISVPW---YLGLMFRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLS 1765
Query: 4296 EVYVADGHWHTFLIGKNGTATVLSVDRIYNRDIIHPTQDFG-------------GLDVLT 4342
+ V DG WH LI + + ++ T D+G GL V +
Sbjct: 1766 GLRVTDGEWHHLLIELKNVKEDSEM-----KHLVTMTLDYGMDQNKADIGGMLPGLTVRS 1820
Query: 4343 ISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSGKHSLASISKTDPSVKIGCRGPN 4402
+ +GG ++ + GF GC+ + GG + +L + VK GC +
Sbjct: 1821 VVVGGASEDKV---SVRRGFRGCMQGVRMGGTP---TNVATLNMNNALKVRVKDGCDVDD 1874
Query: 4403 ICASNPCWGDLLCINQWYAYRCVPP---------GDCASHPCQNGGSC--EPGLHSGFTC 4451
C S+PC + C + W Y CV C +PC+N G+C PG G+ C
Sbjct: 1875 PCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVC 1934
Query: 4452 SCPDSHTGRTCEMVVACLGVLCPQG 4476
C SH G CE L + CP+G
Sbjct: 1935 ECGPSHYGPYCENK---LDLPCPRG 1956
Score = 465 bits (1197), Expect = e-130
Identities = 334/982 (34%), Positives = 487/982 (49%), Gaps = 70/982 (7%)
Query: 588 YDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTIS 645
Y V++ EN P GT +L L A G+ V + ++ E R FR+D +G +ST S
Sbjct: 250 YQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAVSTDS 309
Query: 646 SLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGG 705
LDRE + + L V A D +PP+S+ I V + D ND+SPVF +Y ++EN G
Sbjct: 310 VLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVG 369
Query: 706 SYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVA 765
+ T+ A+D D N ++Y + G FQ+N SGV+STR LDREE YQL + A
Sbjct: 370 YEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLLVEA 429
Query: 766 TDGGNLQSPNQAIVT--ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN 823
D G P A T I V D DN P FS+ Y V E+V L V V A+ D
Sbjct: 430 NDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQG 489
Query: 824 SN--ISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG----TVTGDT 877
N I Y I +G+ G F ++ ++G L N +D E+ Y L + A G +
Sbjct: 490 QNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSG 549
Query: 878 MVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSL----- 932
+V++ V D+NDN P F+ + V+EN G+ + +AVD D G N + Y L
Sbjct: 550 VVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTAS 609
Query: 933 ------KQNPKN-------LFAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSS 978
PKN F I+ +G I++ LD Y + A D G P +SS
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 979 SVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEG 1038
S +++ V DVNDN PVF Q +YE+ L+E V S +QA D+D AN I Y + G
Sbjct: 670 STSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSVITYQLTGG 727
Query: 1039 NTGDAFGIFPD---GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVND 1095
NT + F + G + + LD + + +YVL V ASD S T +V + + D N
Sbjct: 728 NTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGT---RSHTAHVLINVTDANT 784
Query: 1096 NRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEI 1155
+RP+F S++YT E++ G+ + +SA D+D G N + Y + P F + SG +
Sbjct: 785 HRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTM 844
Query: 1156 TNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFY 1215
+ D E+ ++ T++A D GIPQ D T+ + + D NDNAP+FL DFY
Sbjct: 845 YTMMELDYEN------QVAYTLTIMAQDNGIPQK-SDTTTLEILILDANDNAPQFLWDFY 897
Query: 1216 QATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE-ERQFAIDSTSGQVTLIGKLD 1274
Q +I E A T +L+VSA+D D G NG + Y+ G++ + F I+ TSG + +LD
Sbjct: 898 QGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLD 957
Query: 1275 YEATPAYSLVIQAVDSGT-IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGEL 1333
E Y+L AVD G+ PL+++ + + ILD NDN P F K L + V EN +G +
Sbjct: 958 RENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSV 1017
Query: 1334 VSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAK 1393
V+ + A D D G NA + Y I + F + G + +LDFE + Y L + A
Sbjct: 1018 VAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQAT 1077
Query: 1394 DQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDI-FKSIVEN----IPIGTSVISVTAHDPD 1448
P S +V I + D NDNPP P I F + V N P G + + AHDP
Sbjct: 1078 S---APLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGV-IGCIPAHDP- 1132
Query: 1449 ADINGQLSYTIIQQMPRGNH---FTIDEVKGTIYTNAEID--REFANLFELTVKANDQAV 1503
D++ L+YT +Q GN +D G + + ++D R L E++V +V
Sbjct: 1133 -DVSDSLNYTFVQ----GNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSV 1187
Query: 1504 PIETRRYALKNVTILVTDLNDN 1525
+ VTI+ D+ N
Sbjct: 1188 ----TAFCTLRVTIITDDMLTN 1205
Score = 416 bits (1069), Expect = e-115
Identities = 322/1000 (32%), Positives = 481/1000 (48%), Gaps = 73/1000 (7%)
Query: 1740 FPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDS----FRIDPESGD 1795
FP + + EN G+ I+QL A EG V+Y + D+ FRID +G
Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGA 304
Query: 1796 LIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIPE 1852
+ LDRE + + L V+A D +S+ I + V D NDH+P F + Y + E
Sbjct: 305 VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRE 364
Query: 1853 DTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYY 1912
+ G V I A+D DS +N + Y V D +F LN +GV + +LD E Y
Sbjct: 365 NLEVGYEVLTIRASDRDSPINANLRYRVLGGAWD-VFQLNESSGVVSTRAVLDREEAAEY 423
Query: 1913 ILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNV 1968
L V A D G T VY + D NDN P FS +Y + E++ + + VL
Sbjct: 424 QLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQA 483
Query: 1969 TDADDGINSQLTYSIASGDSLGQFTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIP 2027
TD D G N+ + YSI SG+ GQF + +G+L V+ LD E Y+L ++ D + P
Sbjct: 484 TDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPP 543
Query: 2028 ASRFTSTAQVSIILLDVNDNPPTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIE 2086
S+ VS+ +LDVNDN P F+S P + EN P+ V QA D DSG N+ +
Sbjct: 544 L--INSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLH 601
Query: 2087 YTLLNPLGN------------------KFSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
Y L++ F I G + + ELDREEV +Y+ V A D
Sbjct: 602 YRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVD 661
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P +SSST V + VLD+NDN+P+F Q Y++ +NE+ G+ ++ + A D D N
Sbjct: 662 HGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSV 719
Query: 2189 VRYGIVNGNTNQEFRIDSVTGA--ITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVS 2246
+ Y + GNT F + S G IT+A PLD ++ Y L V A+D R+ T+ V
Sbjct: 720 ITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD---GTRSHTAHVL 776
Query: 2247 IVLLDINDFVPVFELSPYSVNVPEN--LGTLPRTILQVVARDDDRGSNSKLSYVLFGGNE 2304
I + D N PVF+ S Y+V+V E+ +GT +I + A D+D G N++++YV+ +
Sbjct: 777 INVTDANTHRPVFQSSHYTVSVSEDRPVGT---SIATLSANDEDTGENARITYVI--QDP 831
Query: 2305 DNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPT 2363
F + SG + LD E + + L I A D+G P + T T+ +++ D NDN P
Sbjct: 832 VPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQ 891
Query: 2364 FASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII-----GGNSQFTINPSTGQII 2418
F Y +I EDAP T +L V+A+D D+ N + G+ F I P++G I
Sbjct: 892 FLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 2419 TSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSP 2478
T LDRE Y L + D GSP PLS+S + VT+ D+NDN P F+ +
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEEN 1011
Query: 2479 TLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLRGAIMAAGPLNGASEVTFS 2537
GS V + D D GPN+++ Y + G F +D L G + A L+ +
Sbjct: 1012 NPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREY- 1070
Query: 2538 VHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQ-TFMFPENQPVSSLVTTITGSSLRG 2596
V V S P TV + V++ D P V Q F +S T + G
Sbjct: 1071 VLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAH 1130
Query: 2597 EP-----MSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSS 2651
+P ++Y GN +D TG++ +S+ LD + + ++ + D G ++
Sbjct: 1131 DPDVSDSLNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSD-GIHSVTA 1189
Query: 2652 YEKLDITVL--DVNDNAPIFKEDPFISEILENLSPRKILT 2689
+ L +T++ D+ N+ I+ LEN+S K L+
Sbjct: 1190 FCTLRVTIITDDMLTNS--------ITVRLENMSQEKFLS 1221
Score = 402 bits (1034), Expect = e-111
Identities = 290/952 (30%), Positives = 475/952 (49%), Gaps = 57/952 (5%)
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVN---EDDEDGIFFLNPITG 1896
KF P Y + E+ G+L+ + A G ++Y + ++ G F ++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 1897 VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNIL--DVNDNPPIFSLNSYSTSLM 1954
+ +LD E ++ ++L V+A D + Y +L D ND+ P+F + Y +
Sbjct: 304 AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVR 363
Query: 1955 ENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQSFY 2014
ENL VG VL +D D IN+ L Y + G + +GV+ LDRE + Y
Sbjct: 364 ENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEY 423
Query: 2015 NLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPK-LTYIPENTPIDTVVFKAQ 2073
L+V+ +D + P ++TA V I + D NDN P F + +PE+ ++T V + Q
Sbjct: 424 QLLVEANDQGRNPGP-LSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQ 482
Query: 2074 ATDPDSGPNSYIEYTLLNP-LGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQP 2132
ATD D G N+ I Y++L+ + +F + ++ G + + LD E+V Y+L++ A D G+P
Sbjct: 483 ATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRP 542
Query: 2133 SLSSSTEVV-VMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRY 2191
L +S+ VV V VLD+NDN PIF + ++ + EN G ++ + A D D G N ++ Y
Sbjct: 543 PLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHY 602
Query: 2192 GIVN-----------GNTNQE------FRIDSVTGAITVAKPLDREKTPTYHLTVQATDR 2234
+V+ G N F+I + +G ITV LDRE+ Y V+A D
Sbjct: 603 RLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDH 662
Query: 2235 GSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSK 2294
GS P + +++VSI +LD+ND PVF Y + + E+ + ++L + ARD D +NS
Sbjct: 663 GSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNED-AAVGSSVLTLQARDRD--ANSV 719
Query: 2295 LSYVLFGGNEDNAFTLSAS---GELGVTQSLDRETKERFVLMITATDSGSPALTGTGTIN 2351
++Y L GGN N F LS+ G + + LD + ++++VL +TA+D G+ + T IN
Sbjct: 720 ITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD-GTRSHTAHVLIN 778
Query: 2352 VIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNS--QFT 2409
V D N + P F S Y ++ ED P GT + ++A+D D +NA I + + QF
Sbjct: 779 VT--DANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFR 836
Query: 2410 INPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHH 2469
I+P +G + T LD E + YTL ++ D G P+ S +T++ + + D NDN P+F
Sbjct: 837 IDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQK-SDTTTLEILILDANDNAPQFLWD 895
Query: 2470 PYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEK--FHIDPLRGAIMAAGP 2527
Y I P + + V+ TD D GPN L Y+ G + F+I+P G I
Sbjct: 896 FYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRR 955
Query: 2528 LNGASEVTFSVH---VKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMF-PENQPVS 2583
L+ + +++ V G P + S + V ++ D + K++ +F EN PV
Sbjct: 956 LDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVG 1015
Query: 2584 SLVTTITGSSLRGEP---MSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIE 2640
S+V I + P + Y I G++ + FQ+D L G + LDFE ++YV+ ++
Sbjct: 1016 SVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQ 1075
Query: 2641 ARDGGFPPFSSYEKLDITVLDVNDNAPIFKE-----DPFISEILENLSPRKILTVSAMDK 2695
A P S + I ++D NDN P+ + + +++ + I + A D
Sbjct: 1076 ATSA---PLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDP 1132
Query: 2696 DSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSD 2747
D + L+Y V GN ++ ATGE++ R LD + ++ + SD
Sbjct: 1133 DVSDS--LNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSD 1182
Score = 384 bits (986), Expect = e-105
Identities = 325/1052 (30%), Positives = 488/1052 (46%), Gaps = 77/1052 (7%)
Query: 996 FDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQ 1051
F +Y+V L E+EP + ++ A G ++Y + + G F G
Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGA 304
Query: 1052 LYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEE 1111
+ S LDRE ++ +VL V A D + P SAT +TV+++D ND+ P+F + Y E
Sbjct: 305 VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRE 364
Query: 1112 EQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD-FELHAISGEITNTHQFDRESLMRRR 1170
G V + A D+D N +RY D F+L+ SG ++ DRE
Sbjct: 365 NLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREE----- 419
Query: 1171 GTAVFSFTVIATDQGI-PQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQV 1229
A + V A DQG P PL ATV++ ++D NDN P+F + Y + E T V
Sbjct: 420 -AAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAV 478
Query: 1230 LRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVD 1289
LRV A+D D+G N IHYSI+ GN QF + S SG + +I LD+E YSL I+A D
Sbjct: 479 LRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQD 538
Query: 1290 SGTIPL-NSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNA 1348
G PL NS+ +++ +LD NDN P F S VLEN+ +G V + A D+DSG+NA
Sbjct: 539 GGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENA 598
Query: 1349 DLYYSITGTNN-----------------HGTFSISPNTGSIFLAKKLDFETQSLYKLNIT 1391
L+Y + T + F I ++G I + +LD E Y +
Sbjct: 599 RLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVE 658
Query: 1392 AKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADI 1451
A D G PP SS+ SV I V D NDN P F + E+ +G+SV+++ A D DA
Sbjct: 659 AVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDA-- 716
Query: 1452 NGQLSYTIIQQMPRGNHFTIDEVKG--TIYTNAEIDREFANLFELTVKANDQAVPIETRR 1509
N ++Y + R N F + +G I +D + + L V A+D R
Sbjct: 717 NSVITYQLTGGNTR-NRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGT------R 769
Query: 1510 YALKNVTILVTDLNDNVPMFISQN-ALAADPSAVIGSVLTTIMAADPDEGANGEIEYEII 1568
+V I VTD N + P+F S + ++ +G+ + T+ A D D G N I Y +I
Sbjct: 770 SHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITY-VI 828
Query: 1569 NGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIILQGLD-- 1625
F +D SG + L +Q+ Y L + A D G ++ TT L I++ +
Sbjct: 829 QDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDN 888
Query: 1626 GPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGR 1685
P F Y + E P T+++ + A P + + + + G F I
Sbjct: 889 APQFLWDFYQGSIFEDAPPSTSILQVSATDR--DSGPNGRLLYTFQGGDDGDGD-FYIEP 945
Query: 1686 HTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML 1745
+G+I+T LDRE A +Y + A+++ + P + E+++T+ DINDN P+F D L
Sbjct: 946 TSGVIRTQRRLDRENVA-VYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDEL 1004
Query: 1746 DLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDR 1804
+L VEEN GS + ++ A D DEG NA + Y I+ G F++D +GDL A LD
Sbjct: 1005 ELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDF 1064
Query: 1805 ERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFD----IPEDTIPGSLV 1860
E R +Y L+V+A S ++I + D ND+ P F+ ++ P ++
Sbjct: 1065 EVRREYVLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVI 1124
Query: 1861 AAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAED 1920
I A D D V+ + Y + +E + L+P TG L+R LD ++ V D
Sbjct: 1125 GCIPAHDPD--VSDSLNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSD 1182
Query: 1921 G---GGQFTTIRVYFNILDVNDNPPIFSLNSYS-----TSLMENLPVG---------STV 1963
G F T+RV D+ N L + S + L+ G V
Sbjct: 1183 GIHSVTAFCTLRVTIITDDMLTNSITVRLENMSQEKFLSPLLALFVEGVAAVLSTTKDDV 1242
Query: 1964 LVFNV---TDADDGINSQLTYSIASGDSLGQF 1992
VFNV TD I + ++ G GQF
Sbjct: 1243 FVFNVQNDTDVSSNILNVTFSALLPGGVRGQF 1274
Score = 377 bits (968), Expect = e-103
Identities = 293/896 (32%), Positives = 435/896 (48%), Gaps = 93/896 (10%)
Query: 45 PRQVFQVLEEQPPGTLVGTIQ---TRPGFTYRLS---------ESHALFAINSSTGALYT 92
P + E +P GTL+ + T G R+S S F I+S+TGA+ T
Sbjct: 248 PNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGAVST 307
Query: 93 TSTIDRESLPSDVINLVVLS------SAPTYPTEVRVLVRDLNDNAPVFPDPSIVVTFKE 146
S +DRE+ + V+ + + SA TY T VLV+D ND++PVF +E
Sbjct: 308 DSVLDRETKETHVLRVKAVDYSTPPRSATTYIT---VLVKDTNDHSPVFEQSEYRERVRE 364
Query: 147 DSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKG 206
+ G +V+ A+D D N + YR++ G D+ G + ++
Sbjct: 365 NLEVGYEVLTIRASDRDSPINA--NLRYRVLGG------AWDVFQLNESSGV---VSTRA 413
Query: 207 GLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVT----VQDINDNPPVFGSSHYQAGVPED 262
LDRE +YQLLVE D+G + G L T V+D NDN P F +Y VPED
Sbjct: 414 VLDREEAAEYQLLVEANDQG--RNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPED 471
Query: 263 AVVGSSVLQVAAADADEGTNADIRYRLQDEGT--PFQMDPETGLITVREPLDFEARRQYS 320
+ ++VL+V A D D+G NA I Y + F + +G++ V PLDFE ++YS
Sbjct: 472 VGLNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYS 531
Query: 321 LTVQAMDRGVPSLTGRAEAL-IQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVAL 379
L+++A D G P L + + +Q+LDVNDN+P+ F ++ A+V EN +G V
Sbjct: 532 LSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPI-----FVSSPFQATVLENVPLGYPVVH 586
Query: 380 LTVTDADSPAANGNISVQI-------LGGNE----------QRHFEVQSSKVPNLSLIKV 422
+ DADS N + ++ LGG F++ +S I V
Sbjct: 587 IQAVDADS-GENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSS----GWITV 641
Query: 423 ASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRV 482
+ LDRE + Y+ V D +G+PP SS S+ I V D+ND+ PVF+Q Y +
Sbjct: 642 CAELDREEVEHYSFGVEAVD-HGSPP------MSSSTSVSITVLDVNDNDPVFTQPTYEL 694
Query: 483 NLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEH--SGLVTTGSSGGL 540
L+E+A GS V + A D D+ N+ + Y + GN F +S GL+T L
Sbjct: 695 RLNEDAAVGSSVLTLQARDRDA--NSVITYQLTGGNTRNRFALSSQRGGGLITLALP--L 750
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
D + Q VL ++A D + A +++ + D N +PVF Q Y VSV E+ P GT
Sbjct: 751 DYKQEQQYVLAVTASD---GTRSHTAHVLINVTDANTHRPVF-QSSHYTVSVSEDRPVGT 806
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVL 660
+ L A D D G+N + + +Q+ FR+DP SG + T+ LD E Q Y+L ++
Sbjct: 807 SIATLSANDEDTGENARITYVIQDPVP---QFRIDPDSGTMYTMMELDYENQVAYTLTIM 863
Query: 661 ATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGT 720
A D G P +S + + +LD NDN+P F Y I E+ P + I VSATD D G
Sbjct: 864 AQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGP 923
Query: 721 NGTVKYSISAGD--RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAI 778
NG + Y+ GD F + SGVI T+ LDRE Y L +A D G+ + ++
Sbjct: 924 NGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASV 983
Query: 779 -VTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQ 835
+ +T+LD DN P+F + V EN +G V + A+ D N+ I Y I GD
Sbjct: 984 EIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDM 1043
Query: 836 KGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSP 891
+ F ++ + G L +D E + Y L V A+ + V+I + D NDN P
Sbjct: 1044 RHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSRATVHILLVDQNDNPP 1099
Score = 367 bits (943), Expect = e-100
Identities = 275/841 (32%), Positives = 404/841 (48%), Gaps = 79/841 (9%)
Query: 80 LFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYP------TEVRVLVRDLNDNAP 133
+F +N S+G + T + +DRE + LV + P V + V D NDN P
Sbjct: 399 VFQLNESSGVVSTRAVLDREEAAEYQL-LVEANDQGRNPGPLSATATVYIEVEDENDNYP 457
Query: 134 VFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNP 193
F + + VV ED V+ ATD D G N H Y I+ GN AG+F L
Sbjct: 458 QFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIH--YSILSGNVAGQFYL------ 509
Query: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKR-RGYLQVNVTVQDINDNPPVFGS 252
L +++ LD E +Y L ++ +D G P V+V V D+NDN P+F S
Sbjct: 510 HSLSGILDVINP--LDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVS 567
Query: 253 SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGT------------------ 294
S +QA V E+ +G V+ + A DAD G NA + YRL D +
Sbjct: 568 SPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPD 627
Query: 295 -PFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVV 353
PFQ+ +G ITV LD E YS V+A+D G P ++ I +LDVNDNDPV
Sbjct: 628 FPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPV- 686
Query: 354 KFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSK 413
F + ++E+A VG+ V L D D AN I+ Q+ GGN + F + S +
Sbjct: 687 ----FTQPTYELRLNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNTRNRFALSSQR 739
Query: 414 VPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPP 473
LI +A LD ++ Y L V+ SD RS A ++I V D N H P
Sbjct: 740 --GGGLITLALPLDYKQEQQYVLAVTASDG----------TRSHTAHVLINVTDANTHRP 787
Query: 474 VFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVT 533
VF Y V++SE+ P G+ ++ +SA D D+G NA + Y V + + F I SG +
Sbjct: 788 VFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITY--VIQDPVPQFRIDPDSGTMY 845
Query: 534 TGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVV 593
T LD E L I A+D G+ K L + +LD ND P F + Y S+
Sbjct: 846 TMME--LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLW-DFYQGSIF 902
Query: 594 ENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQA 653
E+AP T +L + ATD D G NG + ++ Q + F ++P SG + T LDRE A
Sbjct: 903 EDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVA 962
Query: 654 FYSLLVLATDLGSP-PQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVS 712
Y+L LA D GSP P S+ I V++LDINDN+P+F + ++EN P GS + +
Sbjct: 963 VYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIR 1022
Query: 713 ATDPDLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNL 771
A DPD G N + Y I GD R FQ++ +G + + LD E + Y L + AT +
Sbjct: 1023 ANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLV 1082
Query: 772 QSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYH-------VGSVSASTMDLNS 824
++A V I ++D DNPPV ++F N +G + A D++
Sbjct: 1083 ---SRATVHILLVDQNDNPPVLPDFQ---ILFNNYVTNKSNSFPTGVIGCIPAHDPDVSD 1136
Query: 825 NISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG--TVTGDTMVNIT 882
+++Y G++ + ++ TG+L + +D ++V S G +VT + +T
Sbjct: 1137 SLNYTFVQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVT 1196
Query: 883 V 883
+
Sbjct: 1197 I 1197
Score = 358 bits (918), Expect = 1e-97
Identities = 267/942 (28%), Positives = 450/942 (47%), Gaps = 67/942 (7%)
Query: 2364 FASKAYFTTIPEDAPTGTDVLLVNAS-DADASKNAVIRIIGG------NSQFTINPSTGQ 2416
F Y + E+ P GT +L ++A + + V + G F I+ +TG
Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGA 304
Query: 2417 IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIP 2476
+ T ++LDRETK+ + L V D +P P S++T + V V D ND+ P F+ Y +
Sbjct: 305 VSTDSVLDRETKETHVLRVKAVDYSTP-PRSATTYITVLVKDTNDHSPVFEQSEYRERVR 363
Query: 2477 SPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNG--ASEV 2534
G V + +D D N+ L Y + G + F ++ G + L+ A+E
Sbjct: 364 ENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEY 423
Query: 2535 TFSVHVKDGGSFPKTDSTTVTVRFVNKAD----FPKVRAKEQTFMFPENQPVSSLVTTIT 2590
V D G P S T TV ++ D +P+ + PE+ +++ V +
Sbjct: 424 QLLVEANDQGRNPGPLSATATV-YIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQ 482
Query: 2591 GSSL---RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP 2647
+ + + Y I SGN+ F + L+G + + PLDFE +QKY + I+A+DGG P
Sbjct: 483 ATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRP 542
Query: 2648 PF-SSYEKLDITVLDVNDNAPIFKEDPFISEILENLS-PRKILTVSAMDKDSGPNGQLDY 2705
P +S + + VLDVNDN PIF PF + +LEN+ ++ + A+D DSG N +L Y
Sbjct: 543 PLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHY 602
Query: 2706 EIVNG-----------------NMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDK 2748
+V+ + F I++++G I LDRE+V HY +++ D
Sbjct: 603 RLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDH 662
Query: 2749 GSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAIS 2807
GSP S+S V I +LD NDN P F+Q + + E++ +G +V + D D N++
Sbjct: 663 GSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSVI 720
Query: 2808 RYSIMDASL--PFTINPSTGD--IVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVT 2863
Y + + F ++ G I ++ PL+ + +Y + V+A D + + V I VT
Sbjct: 721 TYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVT 780
Query: 2864 DINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINAT 2923
D N + P F + Y + E +G+ + + A D D G N ++ Y I+ FRI+
Sbjct: 781 DANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPD 840
Query: 2924 TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQF 2983
+G ++ L Y+N + + + + D G P TT+ I I+D+NDNAPQF
Sbjct: 841 SGTMYTMMELDYENQVAY--------TLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF 892
Query: 2984 LKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY-FISNDNHLGKFKLDNDTGWIS 3042
L Y + ++ T +++V+A D+D G N + Y F D+ G F ++ +G I
Sbjct: 893 LWDFYQGSIFEDAPPSTSILQVSA-TDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 3043 VASSLISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTEENYHTPEFSQSHMSATIPES 3101
L + + + A D+G+P PLS+ + +T+ + N + P F + + + E+
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEEN 1011
Query: 3102 HSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHE 3161
+ +GS+V + A D D N I Y I G+ F ++ G L LD+E+ +++
Sbjct: 1012 NPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYV 1071
Query: 3162 MTISAIDGGWVARTGYCSVTVNVIDVNDNSPV-----FLSDDYFPTVLENAPSGTTVIHL 3216
+ + A V+R +V + ++D NDN PV L ++Y + P+G + +
Sbjct: 1072 LVVQATSAPLVSR---ATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG-VIGCI 1127
Query: 3217 NATDADSGTNAVIAYT-VQSSDSDLFVIDPNTGVITTQGFLD 3257
A D D + + YT VQ ++ L ++DP TG + LD
Sbjct: 1128 PAHDPDVSDS--LNYTFVQGNELRLLLLDPATGELQLSRDLD 1167
Score = 343 bits (879), Expect = 3e-93
Identities = 296/1000 (29%), Positives = 453/1000 (45%), Gaps = 77/1000 (7%)
Query: 135 FPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNG-VDHRSYRIIRGNEAGRFRLDITLNP 193
FP P+ V E+ +G ++ A + G V + + G FR+D
Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRID----- 299
Query: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSS 253
S GA + + LDRE + L V+ D P R + V V+D ND+ PVF S
Sbjct: 300 SATGA---VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQS 356
Query: 254 HYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDEGTPFQMDPETGLITVREPLD 312
Y+ V E+ VG VL + A+D D NA++RYR L FQ++ +G+++ R LD
Sbjct: 357 EYRERVRENLEVGYEVLTIRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLD 416
Query: 313 FEARRQYSLTVQAMDRG--VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
E +Y L V+A D+G L+ A I++ D NDN P F + V E+
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYP-----QFSEQNYVVQVPED 471
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
+ T V + TD D N I IL GN F + S ++ V + LD E
Sbjct: 472 VGLNTAVLRVQATDRDQ-GQNAAIHYSILSGNVAGQFYLHSLS----GILDVINPLDFED 526
Query: 431 IPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPP 490
+ Y+L++ D G PP + S V S+ + D+ND+ P+F ++ + E P
Sbjct: 527 VQKYSLSIKAQDG-GRPP---LINSSGVVSVQVL--DVNDNEPIFVSSPFQATVLENVPL 580
Query: 491 GSYVSGISATDGDSGLNANLRYSIVS------GNGLGW-----------FHISEHSGLVT 533
G V I A D DSG NA L Y +V G G F I SG +T
Sbjct: 581 GYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWIT 640
Query: 534 TGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVV 593
+ LDRE + A D G P S + +T+LDVND PVF+QP Y++ +
Sbjct: 641 VCAE--LDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPT-YELRLN 697
Query: 594 ENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTIS-SLDREEQ 652
E+A G+ +L L+A D D N + + L T R G L T++ LD +++
Sbjct: 698 EDAAVGSSVLTLQARDRDA--NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQE 755
Query: 653 AFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVS 712
Y L V A+D +S A + +++ D N + PVF Y + E+ P G+ I T+S
Sbjct: 756 QQYVLAVTASD---GTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLS 812
Query: 713 ATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQ 772
A D D G N + Y I +F+++ SG + T M LD E + AY L I+A D G Q
Sbjct: 813 ANDEDTGENARITYVIQ-DPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQ 871
Query: 773 SPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDL--NSNISYLI 830
+ + I +LD DN P F Y +FE+ + VSA+ D N + Y
Sbjct: 872 KSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTF 931
Query: 831 TTGDQ-KGMFAINQVTGQLTTANVIDREEQSFYQLKVVA----SGGTVTGDTMVNITVKD 885
GD G F I +G + T +DRE + Y L +A S ++ + +T+ D
Sbjct: 932 QGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILD 991
Query: 886 LNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINE 944
+NDN+P F + + V EN G + + +A DPDEG N ++Y + + + ++ F ++
Sbjct: 992 INDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRHFFQLDL 1051
Query: 945 KNGTISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL----- 999
NG + + LD + ++ P +S + + + V D NDN PV
Sbjct: 1052 LNGDLRAMVELDFEVRREYV-LVVQATSAPLVSRATVHILLV-DQNDNPPVLPDFQILFN 1109
Query: 1000 SYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSEL 1058
+Y S S P + A D D + + YT +GN + P G+L + +L
Sbjct: 1110 NYVTNKSNSFPTGV-IGCIPAHDPD--VSDSLNYTFVQGNELRLLLLDPATGELQLSRDL 1166
Query: 1059 DRELQDRYVLMVVASDRAVEPLSA--TVNVTVILEDVNDN 1096
D + LM V+ + ++A T+ VT+I +D+ N
Sbjct: 1167 DNN-RPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLTN 1205
Score = 325 bits (832), Expect = 9e-88
Identities = 242/807 (29%), Positives = 400/807 (49%), Gaps = 58/807 (7%)
Query: 2871 RFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE-----YFRINATTG 2925
+F +Y + E G+ + Q+ A EG +V Y+++ + YFRI++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 2926 EIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLK 2985
+ +L + H V + D P + T +T+ + D+ND++P F +
Sbjct: 304 AVSTDSVLDRETK--------ETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQ 355
Query: 2986 SKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVAS 3045
S+Y V +N++VG +++ + A D+D +N+ + Y + F+L+ +G +S +
Sbjct: 356 SEYRERVRENLEVGYEVLTIRA-SDRDSPINANLRYRVLG-GAWDVFQLNESSGVVSTRA 413
Query: 3046 SLISDLNQNFFITVTAKDKG-NP-PLSSQATVHITVTEENYHTPEFSQSHMSATIPESHS 3103
L + + + V A D+G NP PLS+ ATV+I V +EN + P+FS+ + +PE
Sbjct: 414 VLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG 473
Query: 3104 IGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMT 3163
+ + V V A DRD N I YSI SGN G F ++S +GIL + LD+E QK+ ++
Sbjct: 474 LNTAVLRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLS 533
Query: 3164 ISAIDGG---WVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATD 3220
I A DGG + +G V+V V+DVNDN P+F+S + TVLEN P G V+H+ A D
Sbjct: 534 IKAQDGGRPPLINSSGV--VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVD 591
Query: 3221 ADSGTNAVIAYTVQSSDSDL------------------FVIDPNTGVITTQGFLDFETKQ 3262
ADSG NA + Y + + S F I ++G IT LD E +
Sbjct: 592 ADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVE 651
Query: 3263 SYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFA 3322
Y V+A + S +V+I + N+ P F Y ++E A G+ V + A
Sbjct: 652 HYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQA 711
Query: 3323 SDRDLGTDGEVHYLIFGNSRKKGFQINKKT--GQIYVSGILDREKEERVSLKVLAKNFGS 3380
DRD + + Y + G + + F ++ + G I ++ LD ++E++ L V A +
Sbjct: 712 RDRD--ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD--- 766
Query: 3381 IRGADIDEVTVNVTVLDAN-DPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSR 3439
G V + V DAN P+F + Y+V +SE P+GT + +SA D D+ + +R
Sbjct: 767 --GTRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGEN-AR 823
Query: 3440 FSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVT 3499
+Y I + F I+P +G + ELD E Y L+++A D+G P + + +L +
Sbjct: 824 ITYVI--QDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEIL 881
Query: 3500 LEDINDNGP--MLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
+ D NDN P + +G + E+ P T ++ + +TD D PN G Y
Sbjct: 882 ILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPN-GRLLYTFQGGDDGDGD 940
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVP-QMSSTGTVHITVIDQNDNPSQSR 3615
F + T+GV+ T R +DRE +A + L + D G P +S++ + +T++D NDN
Sbjct: 941 FYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFE 1000
Query: 3616 TVEIFVNYYGNLFPGGILGSVKPQDPD 3642
E+ + N G ++ ++ DPD
Sbjct: 1001 KDELELFVEENNPVGSVVAKIRANDPD 1027
Score = 62.4 bits (150), Expect = 1e-08
Identities = 41/129 (31%), Positives = 56/129 (43%), Gaps = 29/129 (22%)
Query: 3859 CEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNF 3918
C++D D C SPC CH+ +SC C G+ G C ++ C +PC+N C
Sbjct: 1870 CDVD-DPCTSSPCPPNSRCHDAWEDYSCVCDKGYLGINC---VDACHLNPCENMGACVRS 1925
Query: 3919 PGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGK------H 3972
PGS GY CEC P G C++ +D CP G +G H
Sbjct: 1926 PGS-----PQGYV----------CECGPSHYGPYCENKLD---LPCPRGWWGNPVCGPCH 1967
Query: 3973 CELNSYGFE 3981
C + S GF+
Sbjct: 1968 CAV-SKGFD 1975
Score = 49.7 bits (117), Expect = 7e-05
Identities = 44/181 (24%), Positives = 68/181 (37%), Gaps = 45/181 (24%)
Query: 3804 DSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDI 3863
D+C PC+N G+C+R P Q ++C+C P + G +CE +
Sbjct: 1909 DACHLNPCENMGACVRS------------------PGSP-QGYVCECGPSHYGPYCENKL 1949
Query: 3864 DECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFN 3923
D PC G + + G C+ GF + D N+ NG
Sbjct: 1950 D----LPCPRGWWGNPVCGPCHCAVSKGF-----DPDCNK------TNG----------Q 1984
Query: 3924 CVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGFEEL 3983
C CK Y + + + C+C P S + + C C GV G+ C F E+
Sbjct: 1985 CQCKENYYKLLAQDTCLPCDCFP-HGSHSRTCDMATGQCACKPGVIGRQCNRCDNPFAEV 2043
Query: 3984 S 3984
+
Sbjct: 2044 T 2044
>gi|216548385 dachsous 2 isoform 2 [Homo sapiens]
Length = 1369
Score = 503 bits (1295), Expect = e-141
Identities = 418/1312 (31%), Positives = 620/1312 (47%), Gaps = 132/1312 (10%)
Query: 39 WVHGAEPRQVFQVL----EEQPPGTLVGTI-------QTRPGFTYRLSE----SHAL--F 81
W Q+F + E PP TLVG I Q + G + LSE S L F
Sbjct: 57 WAASGSSAQLFNLTLSVDEGLPPDTLVGDIRAGLPAAQQQEGSGFFLSEDSDDSPLLDDF 116
Query: 82 AINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVLVRDLNDNAPVFPDPSIV 141
++ TG + T +DRE L A +V + V D+ND++P FP S+
Sbjct: 117 HVHPDTGIIRTARRLDRERRDHYSFVAATLLGAVV---QVEIRVNDVNDHSPRFPLDSLQ 173
Query: 142 VTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNE-----AGRF---------RL 187
+ E S G L A D D G + Y +++ ++ AG F L
Sbjct: 174 LDVSELSPPGTAFRLPVAHDPDAGLFST--QGYTLVQPSDLPKDPAGPFFQLRYRTPGPL 231
Query: 188 DITLNPSGEGAF--LHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDIND 245
L P L LV LDRE ++L +E D G P+R G L V + V D ND
Sbjct: 232 PSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDEND 291
Query: 246 NPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP---------- 295
NPPVF Y+A V EDA G+ V +V A D D G N +RY ++ P
Sbjct: 292 NPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALG 351
Query: 296 ----FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDP 351
F ++ +G++ V PLD EA+ + L V+A D G I +LDVNDN P
Sbjct: 352 DAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRP 411
Query: 352 VVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSP--------------AANGNISVQ 397
+ F A V E A+ G VA ++V+DAD +G+IS+
Sbjct: 412 AIHV-LFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLS 470
Query: 398 ILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSS 457
+ GG + F + P + + V LDRE Y L + V+ + G+PP S+
Sbjct: 471 LEGG--EGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLL-VATDAGSPP------LST 521
Query: 458 VASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGD--SGLNANLRYSIV 515
+L++ V D+ND PP+FSQQ Y+ ++SE A PG+ V +SA+D D +A LRY++V
Sbjct: 522 EETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVV 581
Query: 516 SGN---GLG--------------WFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQG 558
+ LG F I SG ++T + LDRE+ + L + A+D G
Sbjct: 582 QLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRT--LDREVQEAVELKVVAQDLG 639
Query: 559 VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV 618
P + + +T+ DVND +P+F + + Y+ ++ E+AP G L + A+D D G G +
Sbjct: 640 EPPLSATCLVSITVDDVNDNEPIFWR-QVYNATIAEHAPVGHCFLQVTASDADSGLYGFI 698
Query: 619 RFSLQE---AETDRRSFRLDPVSGRLSTISSLDRE-EQAFYSLLVLATDLGSPPQSSMAR 674
+SL + + ++FR+DP G++ +DRE + A Y LLV A D G S+ A
Sbjct: 699 EYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGG--LSAQAF 756
Query: 675 INVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGD-R 733
+ V L D+NDN PVF P Y I + G+ I V ATD D G GTV Y + G+
Sbjct: 757 VRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVS 816
Query: 734 SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVF 793
S F +++ +G+I + L E T L + A DGG L + A VTI + T P F
Sbjct: 817 SLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEF 876
Query: 794 SQVAYSFVVFENVALGYHVGSVSA-STMDLNSNISYLITTGDQKGMFAINQVTGQLTTAN 852
+ Y+F+V+E+V +G+V A ++ + I Y I++GD G F+I+ G + T
Sbjct: 877 ERPKYTFLVYEDVPEDSPIGTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRK 936
Query: 853 VIDREEQSFYQLKVVASGGT--VTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGH 910
+D E Q L V A G+ T VNITV D+NDN P FL+ + + + + G
Sbjct: 937 PLDHETQPVVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGT 996
Query: 911 SIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDV-HAGSYQIEILAS 969
+++ A+A D D G NG++ YS+ +FAI+ G + L G L + + A
Sbjct: 997 ALYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAE 1056
Query: 970 DMGVPQLSSSVILTVYVHDVNDNSP--VFDQLSYEVTLSESEPVNSRFFKVQASD-KDSG 1026
D GV ++ ++LTV + + ++SP F+ L Y+V +SES ++ + QA
Sbjct: 1057 DQGVHPQAALLVLTVVI-EKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQR 1115
Query: 1027 ANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLMVVA---SDRAVEPLSA 1082
A + Y++ FGI P G +Y++ + D E Y V A D ++ +S
Sbjct: 1116 AASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVST 1175
Query: 1083 TVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMV 1142
TV V V D NDN P F EE +GK++A+D D G NG++ Y
Sbjct: 1176 TVIVRV--WDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSD 1233
Query: 1143 QPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKD 1202
F+++ +GE+ N DRE RG TV+ TD+G P P V+V + D
Sbjct: 1234 GKFFKMNPNTGELINWVALDRE----HRGH--HEMTVLVTDRGSP-PRNATMAVYVSVTD 1286
Query: 1203 INDNAPKFL-----KDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSI 1249
INDN P F K+ + + N+ V V A D DEGNN + YS+
Sbjct: 1287 INDNRPFFPQCLPGKELHVKVLEGQPVNML-VTTVFAKDPDEGNNAEVTYSV 1337
Score = 424 bits (1089), Expect = e-117
Identities = 379/1294 (29%), Positives = 562/1294 (43%), Gaps = 147/1294 (11%)
Query: 1640 EGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDRE 1699
EG P T V I A P + + +S ++ + F + TGII+TA LDRE
Sbjct: 75 EGLPPDTLVGDIRAGLPAAQQQEGSGFFLSEDSDDSPLLDDFHVHPDTGIIRTARRLDRE 134
Query: 1700 QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKI 1759
+ D Y+ +T +VEI + D+ND+ P FP D L L V E G+
Sbjct: 135 RR------DHYSFVAATLLGAV--VQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAF 186
Query: 1760 MQLTAMDADEGANALVTYTIISGADDSFRIDP---------------------------E 1792
A D D G + YT++ +D DP E
Sbjct: 187 RLPVAHDPDAGLFSTQGYTLVQPSD--LPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLE 244
Query: 1793 SGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFD 1849
DL+ RRLDRE + + L + A DG ++ + + + V D ND+ P F + Y
Sbjct: 245 PLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAA 304
Query: 1850 IPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGI------------FFLNPITGV 1897
+ ED PG+ V + ATD D G NG + Y V G F + ++GV
Sbjct: 305 VREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGV 364
Query: 1898 FNLTRLLDYEVQQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPP----IFSLNSYST 1951
+ R LD E Q ++ L V A DGG + T+RV +LDVNDN P +F
Sbjct: 365 VRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVA 424
Query: 1952 SLMENLPVGSTVLVFNVTDAD------DGINSQLTYSIASGD-------SLGQFTVDKNG 1998
+ E G V +V+DAD D +L + G G F + G
Sbjct: 425 RVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGG 484
Query: 1999 -----VLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLS 2053
L V LDRES+ Y L++ D P S + + + + D+ND PP F
Sbjct: 485 PPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLS---TEETLLLRVADLNDQPPLFSQ 541
Query: 2054 PKL-TYIPENTPIDTVVFKAQATDPDSG--PNSYIEYTLLN------------------P 2092
+ E TVV A+D D ++++ YT++
Sbjct: 542 QHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAE 601
Query: 2093 LGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNP 2152
G F+I + G + LDRE L VVA D G+P LS++ V + V D+NDN P
Sbjct: 602 CGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEP 661
Query: 2153 IFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNG----NTNQEFRIDSVT 2208
IF + +Y I E+ G +QV A+D D G G + Y + +G Q FRID
Sbjct: 662 IFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHD 721
Query: 2209 GAITVAKPLDREKTP-TYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVN 2267
G I V++ +DRE+ P TY L V+A D G + + V + L D+ND PVF S Y +
Sbjct: 722 GQICVSQDIDRERDPATYDLLVEAKDGGGL--SAQAFVRVDLEDVNDNHPVFNPSTYVTS 779
Query: 2268 VPENLGTLPRT-ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRE 2325
+ + T P T I+ V+A D D G ++Y L GN + FT+ S +G + +T L
Sbjct: 780 ISDE--TQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGIIYLTLPLSHL 837
Query: 2326 TKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAY----FTTIPEDAPTGT 2381
LM++A D G + + + F Y + +PED+P GT
Sbjct: 838 ESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPIGT 897
Query: 2382 DVLLVNASDA-DASKNAVIRIIGGN--SQFTINPSTGQIITSALLDRETKDNYTLVVVCS 2438
V A + ++S+ RI G+ +F+I+P G I T LD ET+ L V +
Sbjct: 898 ----VKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQ-A 952
Query: 2439 DAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPN 2498
GS P SST V +TV DVNDN P F I T PG+ ++ D D G N
Sbjct: 953 QLGSA-PACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRN 1011
Query: 2499 SELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGAS--EVTFSVHVKDGGSFPKTDSTTVTV 2556
+ YS++ F ID G + G L E+T ++ +D G P+ +TV
Sbjct: 1012 GLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTV 1071
Query: 2557 RFVNKADFPKVRAKEQTFMFPENQPVSSLVTTIT------GSSLRGEPMSYYIASGNLGN 2610
+ P + + ++ +S + + G P+ Y +
Sbjct: 1072 VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSA 1131
Query: 2611 TFQIDQLTGQVSISQPLDFEKIQKY----VVWIEARDGGFPPFSSYEKLDITVLDVNDNA 2666
F I TG + + + D+E Q Y WI DG S+ + + V D NDN+
Sbjct: 1132 MFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIP-EDGFLQNVST--TVIVRVWDENDNS 1188
Query: 2667 PIFKEDPFISEILENLSPRKIL-TVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEI 2725
P F D ++ E+ P+ ++ ++A+D DSG NGQL Y +++ F +N TGE+
Sbjct: 1189 PTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDG--KFFKMNPNTGEL 1246
Query: 2726 RSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAH----- 2780
+ LDRE H+ +T+ +D+GSP ++ ++ V +++ D NDN P F Q
Sbjct: 1247 INWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVK 1306
Query: 2781 VPENSPLGYTVTRVTTSDEDIGINAISRYSIMDA 2814
V E P+ VT V D D G NA YS+ A
Sbjct: 1307 VLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSA 1340
Score = 423 bits (1088), Expect = e-117
Identities = 386/1306 (29%), Positives = 592/1306 (45%), Gaps = 138/1306 (10%)
Query: 258 GVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGT--PFQMDPETGLITVREPLDFEA 315
G+P D +VG + AA EG+ + D F + P+TG+I LD E
Sbjct: 76 GLPPDTLVGDIRAGLPAAQQQEGSGFFLSEDSDDSPLLDDFHVHPDTGIIRTARRLDRER 135
Query: 316 RRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGT 375
R YS + L + I++ DVND+ P FP S V E + GT
Sbjct: 136 RDHYSFVAATL------LGAVVQVEIRVNDVNDHSP-----RFPLDSLQLDVSELSPPGT 184
Query: 376 VVALLTVTDADSP--AANGNISVQI-------LGGNEQRHFEV-----------QSSKVP 415
L D D+ + G VQ G Q + SS +
Sbjct: 185 AFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLE 244
Query: 416 NLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVF 475
L L+ + LDRE ++ L + D G P R+ + S+ + V D ND+PPVF
Sbjct: 245 PLDLV-LLRRLDREEAAAHRLQIEAWDG-GRP------RRTGLLSVELRVLDENDNPPVF 296
Query: 476 SQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI----VSGNGLG--------WF 523
Q YR + E+A PG+ V + ATD D G N +RYS+ V G G G +F
Sbjct: 297 EQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYF 356
Query: 524 HISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKP--- 580
+ E SG+V LDRE + L + ARD G P+V+ ++ + +LDVND +P
Sbjct: 357 AVEELSGVVRVWRP--LDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIH 414
Query: 581 VFSQPEGYDVSVVENAPTGTELLMLRATDGD----------------LGDNGTVRFSLQE 624
V EG V E A G + + +D D LGD G++ SL+
Sbjct: 415 VLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGD-GSISLSLEG 473
Query: 625 AETDRRSFRLDPVSGR----LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLL 680
E D F L P L LDRE + Y LL++ATD GSPP S+ + + +
Sbjct: 474 GEGD---FALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVA 530
Query: 681 DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLG--TNGTVKYSI---------- 728
D+ND P+F Y A + E G+ + VSA+D D + ++Y++
Sbjct: 531 DLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLG 590
Query: 729 --------SAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVT 780
+A F ++++SG IST LDRE + A +L++VA D G +V+
Sbjct: 591 SLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVS 650
Query: 781 ITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTG----D 834
ITV D DN P+F + Y+ + E+ +G+ V+AS D L I Y + G +
Sbjct: 651 ITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYSLYDGFLSYE 710
Query: 835 QKGMFAINQVTGQLTTANVIDRE-EQSFYQLKVVAS-GGTVTGDTMVNITVKDLNDNSPH 892
F I+ GQ+ + IDRE + + Y L V A GG ++ V + ++D+NDN P
Sbjct: 711 APQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVRVDLEDVNDNHPV 770
Query: 893 FLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSL-KQNPKNLFAINEKNGTISL 951
F + ++ + Q G I A D D G+ G V Y L N +LF I+ G I L
Sbjct: 771 FNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGIIYL 830
Query: 952 LGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEP 1010
PL + + + + + A D G + +T+++ F++ Y + E P
Sbjct: 831 TLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVP 890
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPD-GQLYIKSELDRELQDRYVLM 1069
+S V+A + + + I Y I+ G+ G F I P G + + LD E Q VL
Sbjct: 891 EDSPIGTVKAREPLNSSE-PIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLT 949
Query: 1070 VVASDRAVEPLSAT-VNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKD 1128
V A + S+T VN+TV+ DVNDN P F T+ + G+ + A D+D
Sbjct: 950 VQAQLGSAPACSSTEVNITVM--DVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRD 1007
Query: 1129 FGPNGEVRYSFEMVQPD-FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGI- 1186
G NG +RYS QP F + G + F SL + + T+ A DQG+
Sbjct: 1008 SGRNGLIRYSIASPQPGVFAIDRALGVL-----FLNGSLGAGEQREL-TLTLRAEDQGVH 1061
Query: 1187 PQPLKDQATVHVYMKDINDNAPKFLKDF--YQATISESAANLTQVLRVSASDVDEGNNGL 1244
PQ TV + ++ ++P + + YQ +SES + +TQ+L+ A +
Sbjct: 1062 PQAALLVLTVVIEKRE---HSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAAS 1118
Query: 1245 -IHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQA-VDSGTIPLNSTCTLN 1302
+ YS+ + F I +G + L + DYE+T Y+ + A + N + T+
Sbjct: 1119 PLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVI 1178
Query: 1303 IDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGT 1362
+ + DENDN+P+F LF+ V E+ ++ +TA D DSG N L Y +
Sbjct: 1179 VRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGKF-- 1236
Query: 1363 FSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFP- 1421
F ++PNTG + LD E + +++ + D+G PPR++TM+V + V D NDN P FP
Sbjct: 1237 FKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQ 1296
Query: 1422 --PG-DIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMP 1464
PG ++ ++E P+ V +V A DPD N +++Y++ P
Sbjct: 1297 CLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSARP 1342
Score = 382 bits (982), Expect = e-105
Identities = 357/1245 (28%), Positives = 567/1245 (45%), Gaps = 130/1245 (10%)
Query: 1258 FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPK 1317
F + +G + +LD E YS V + L + + I + D ND++P FP
Sbjct: 116 FHVHPDTGIIRTARRLDRERRDHYSFVAATL------LGAVVQVEIRVNDVNDHSPRFPL 169
Query: 1318 STLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNN-----HGTF--------- 1363
+L +DV E G A D D+G + Y++ ++ G F
Sbjct: 170 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 229
Query: 1364 ----SISPNTGS------IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDF 1413
+ P + S + L ++LD E + ++L I A D GRP R+ +SV + V D
Sbjct: 230 PLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDE 289
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTI-IQQMPRGN----- 1467
NDNPP F + ++ E+ G V V A D D NG + Y++ +Q+P
Sbjct: 290 NDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGA 349
Query: 1468 -----HFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDL 1522
+F ++E+ G + +DRE +L V+A D E A V+I V D+
Sbjct: 350 LGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEV---ATVRVSIAVLDV 406
Query: 1523 NDNVP----MFISQNALA-ADPSAVIGSVLTTIMAADPD------EGANGEIEYEIINGD 1571
NDN P +F+++ +A A G + + +D D + A GE+ + +G
Sbjct: 407 NDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGS 466
Query: 1572 TDTFIVDRYSGDLRVASALVP--------------SQLIYNLIVSATDLGPERRKSTTEL 1617
+ ++ GD + P S+ +Y L++ ATD G +TE
Sbjct: 467 I-SLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSP--PLSTEE 523
Query: 1618 TIILQGLD----GPVFTQPKYITILKEGEPIGTNVISIEA--ASPRGSE-APVEYYIVSV 1670
T++L+ D P+F+Q Y + E GT V+ + A A GS+ A + Y +V +
Sbjct: 524 TLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQL 583
Query: 1671 RC-------EEKTV-----GRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAF 1718
+ K V G F I +G I T LDRE + L V +
Sbjct: 584 SAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVV--AQDLGEP 641
Query: 1719 PRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYT 1778
P + V IT+ D+NDN P+F + + T+ E+ G +Q+TA DAD G + Y+
Sbjct: 642 PLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYS 701
Query: 1779 IISG-----ADDSFRIDPESGDLIATRRLDRER-RSKYSLLVRA-DDGLQSSDMRINITV 1831
+ G A +FRIDP G + ++ +DRER + Y LLV A D G S+ + + +
Sbjct: 702 LYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVRVDL 761
Query: 1832 SDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFL 1891
DVND+ P F+ Y I ++T PG+ + +LATD DSG+ G + Y + + +F +
Sbjct: 762 EDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTI 821
Query: 1892 NPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIR--VYFNILDVNDNPPIFSLNSY 1949
+ TG+ LT L + L V A+DGGG I V +I P F Y
Sbjct: 822 DSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKY 881
Query: 1950 STSLMENLPVGSTVLVFNVTDADDGINSQ--LTYSIASGDSLGQFTV-DKNGVLKVLKAL 2006
+ + E++P S + A + +NS + Y I+SGD G+F++ + G ++ K L
Sbjct: 882 TFLVYEDVPEDSPI---GTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPL 938
Query: 2007 DRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFL-SPKLTYIPENTPI 2065
D E+Q L VQ Q+ ++ S+ +V+I ++DVNDN P FL + I + TP
Sbjct: 939 DHETQPVVVLTVQA----QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPP 994
Query: 2066 DTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVV 2125
T ++ A+A D DSG N I Y++ +P F+I G + L G L E TLT+
Sbjct: 995 GTALYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLR 1054
Query: 2126 ATDKGQPSLSSSTEVVVMVLDINDNNP--IFAQALYKVEINENTLTGTDIIQVFAAD-GD 2182
A D+G ++ V+ +V++ +++P F +Y+VE++E+ T ++Q A G
Sbjct: 1055 AEDQGVHP-QAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGP 1113
Query: 2183 EGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQA--TDRGSTPRT 2240
+ +RY + + F I TG I + + D E T TY+ V A + G
Sbjct: 1114 QRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNV 1173
Query: 2241 DTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTIL-QVVARDDDRGSNSKLSYVL 2299
T TV + + D ND P F + V E+ +P+ ++ ++ A D D G N +L Y L
Sbjct: 1174 ST-TVIVRVWDENDNSPTFLHDVLFLKVEES--PVPQGVIGKITAIDMDSGKNGQLLYFL 1230
Query: 2300 FGGNEDNAFTLSA-SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVN 2358
++ F ++ +GEL +LDRE + + + TD GSP T + V V D+N
Sbjct: 1231 L--SDGKFFKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDIN 1288
Query: 2359 DNVPTF----ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI 2399
DN P F K + E P V V A D D NA +
Sbjct: 1289 DNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEV 1333
Score = 372 bits (955), Expect = e-102
Identities = 353/1248 (28%), Positives = 547/1248 (43%), Gaps = 141/1248 (11%)
Query: 1785 DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRP 1844
D F + P++G + RRLDRERR YS + L + +++ I V+DVNDH+P+F
Sbjct: 114 DDFHVHPDTGIIRTARRLDRERRDHYSFVAAT---LLGAVVQVEIRVNDVNDHSPRFPLD 170
Query: 1845 VYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE-----DDEDGIFF--------- 1890
D+ E + PG+ +A D D+G+ Y + + D G FF
Sbjct: 171 SLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPGP 230
Query: 1891 ------------LNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT--IRVYFNILD 1936
L P+ V L R LD E + L + A DGG T + V +LD
Sbjct: 231 LPSPLLPGSSSPLEPLDLV--LLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLD 288
Query: 1937 VNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI---------ASGD 1987
NDNPP+F + Y ++ E+ G+ V TD D G N + YS+ + G
Sbjct: 289 ENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGG 348
Query: 1988 SLGQ---FTVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLD 2043
+LG F V++ +GV++V + LDRE+Q+++ LVV+ D P +T +VSI +LD
Sbjct: 349 ALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPE---VATVRVSIAVLD 405
Query: 2044 VNDNPPT----FLSP-KLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFS 2098
VNDN P FL+ + + E V + +D D E T +
Sbjct: 406 VNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEAT------GELG 459
Query: 2099 IGTIDGEVRLT------------------------GELDREEVSNYTLTVVATDKGQPSL 2134
+G DG + L+ G LDRE Y L +VATD G P L
Sbjct: 460 VGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPL 519
Query: 2135 SSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDE--GTNGQVRYG 2192
S+ +++ V D+ND P+F+Q YK ++E GT ++ V A+D DE + +RY
Sbjct: 520 STEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYT 579
Query: 2193 IV-----------------NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRG 2235
+V F IDS +GAI+ + LDRE L V A D G
Sbjct: 580 VVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLG 639
Query: 2236 STPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKL 2295
P + T VSI + D+ND P+F Y+ + E+ + LQV A D D G +
Sbjct: 640 EPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEH-APVGHCFLQVTASDADSGLYGFI 698
Query: 2296 SYVLFGG----NEDNAFTLSA-SGELGVTQSLDRE-TKERFVLMITATDSGSPALTGTGT 2349
Y L+ G AF + G++ V+Q +DRE + L++ A D G L+
Sbjct: 699 EYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGG--GLSAQAF 756
Query: 2350 INVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI--RIIGGN-- 2405
+ V ++DVNDN P F Y T+I ++ GT+++ V A+D D+ + +I GN
Sbjct: 757 VRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVS 816
Query: 2406 SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPR 2465
S FTI+ +TG I + L +L+V D G + ++ V + + P
Sbjct: 817 SLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINA-DVTIHIFQTTLAPAE 875
Query: 2466 FQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSL-SGRNSEKFHIDPLRGAIMA 2524
F+ P T + +P + + + Y + SG KF I P G I
Sbjct: 876 FE-RPKYTFLVYEDVPEDSPIGTVKAREPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRT 934
Query: 2525 AGPLNGASEVTFSVHVK-DGGSFPKTDST--TVTVRFVNKADFPKVRAKEQTFMFPENQP 2581
PL+ ++ + V+ GS P ST +TV VN +R ++ + P
Sbjct: 935 RKPLDHETQPVVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPP 994
Query: 2582 VSS--LVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWI 2639
++ L S R + Y IAS G F ID+ G + ++ L + ++ + +
Sbjct: 995 GTALYLARAEDRDSGRNGLIRYSIASPQPG-VFAIDRALGVLFLNGSLGAGEQRELTLTL 1053
Query: 2640 EARDGGFPPFSSYEKLDITVLDVNDNAP--IFKEDPFISEILENLSPRKILTVSAMDKDS 2697
A D G P ++ L + V++ +++P F+ + E+ E+LSP + +
Sbjct: 1054 RAEDQGVHPQAALLVLTV-VIEKREHSPSWTFEHLVYQVEVSESLSPMTQM-LQTQAHPL 1111
Query: 2698 GPN---GQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKS-SDKGSPSQ 2753
GP L Y + F I TG I R D E Y + + + Q
Sbjct: 1112 GPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQ 1171
Query: 2754 STSVKVMINILDENDNAPRFSQIFSAHVPENSPLGY-TVTRVTTSDEDIGINAISRYSIM 2812
+ S V++ + DENDN+P F E SP+ + ++T D D G N Y ++
Sbjct: 1172 NVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLL 1231
Query: 2813 DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNA 2869
F +NP+TG+++ L+RE + + V D G + V + VTDINDN
Sbjct: 1232 SDGKFFKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNR 1291
Query: 2870 PRFSR----TSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKS 2913
P F + ++ E + VT VFA DPDEG+N +V Y + S
Sbjct: 1292 PFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSS 1339
Score = 370 bits (949), Expect = e-101
Identities = 344/1227 (28%), Positives = 535/1227 (43%), Gaps = 144/1227 (11%)
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRL---- 289
+QV + V D+ND+ P F Q V E + G++ A D D G + Y L
Sbjct: 151 VQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPS 210
Query: 290 ---QDEGTPF-QMDPET----------GLITVREPLDFEARRQ--------YSLTVQAMD 327
+D PF Q+ T G + EPLD R+ + L ++A D
Sbjct: 211 DLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWD 270
Query: 328 RGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADS 387
G P TG +++LD NDN PV F A+V E+AQ G V + TD D
Sbjct: 271 GGRPRRTGLLSVELRVLDENDNPPV-----FEQDEYRAAVREDAQPGAEVCRVRATDRD- 324
Query: 388 PAANGNISVQILGGNEQRHFEVQSSKVPNLS-------------------LIKVASALDR 428
LG N + V++ +VP +++V LDR
Sbjct: 325 -----------LGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDR 373
Query: 429 ERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPP----VFSQQVYRVNL 484
E + L V D P A V R S+A L D+ND+ P +F + +
Sbjct: 374 EAQAWHQLVVEARDGGAEPEVATV--RVSIAVL-----DVNDNRPAIHVLFLTEGGVARV 426
Query: 485 SEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEH---------------S 529
SE A PG YV+ +S +D D + G GLG IS
Sbjct: 427 SEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPP 486
Query: 530 GLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYD 589
G+ G LDRE L + A D G P + L++ + D+ND+ P+FSQ + Y
Sbjct: 487 GVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQ-QHYK 545
Query: 590 VSVVENAPTGTELLMLRATDGDLG--DNGTVRFSLQEAETDRR----------------S 631
SV E A GT ++ + A+D D D+ +R+++ + S
Sbjct: 546 ASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPS 605
Query: 632 FRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYP 691
F +D SG +STI +LDRE Q L V+A DLG PP S+ +++++ D+NDN P+F+
Sbjct: 606 FAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWR 665
Query: 692 VQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRS-----RFQVNAQSGVIS 746
Y A I E+ P G V+A+D D G G ++YS+ G S F+++ G I
Sbjct: 666 QVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQIC 725
Query: 747 TRMALDREEKTA-YQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFEN 805
+DRE A Y L + A DGG L + QA V + + D DN PVF+ Y + +
Sbjct: 726 VSQDIDRERDPATYDLLVEAKDGGGLSA--QAFVRVDLEDVNDNHPVFNPSTYVTSISDE 783
Query: 806 VALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQ 863
G + +V A+ D + ++Y + G+ +F I+ TG + + E +
Sbjct: 784 TQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGIIYLTLPLSHLESTTLS 843
Query: 864 LKVVA-SGGTVTGDTMVNITVKDLNDN--SPHFLQAIESVNVVENWQAGHSIFQAKAVDP 920
L V A GG +T ++T+ F + + V E+ I KA +P
Sbjct: 844 LMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPIGTVKAREP 903
Query: 921 DEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGSYQIEILASDMGVPQLSSSV 980
+ + F+I+ + GTI PLD + + + +G SS
Sbjct: 904 LNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQLGSAPACSST 963
Query: 981 ILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNT 1040
+ + V DVNDN P F + S E+ +S++ P + + +A D+DSG NG I Y+IA
Sbjct: 964 EVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQP 1023
Query: 1041 GDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPL 1099
G F I G L++ L Q L + A D+ V P +A + +TV++E ++ P
Sbjct: 1024 G-VFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEK-REHSPS 1081
Query: 1100 FNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPN---GEVRYSFE--MVQPDFELHAISGE 1154
+ + + E + + GP +RYS E + F + +G
Sbjct: 1082 WTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGW 1141
Query: 1155 ITNTHQFDRESLMRRRGTAVFSFTVIA--TDQGIPQPLKDQATVHVYMKDINDNAPKFLK 1212
I QFD ES T ++F V A + G Q + V V+ D NDN+P FL
Sbjct: 1142 IYLRRQFDYES------TQTYNFRVFAWIPEDGFLQNVSTTVIVRVW--DENDNSPTFLH 1193
Query: 1213 DFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGK 1272
D + ES + +++A D+D G NG + Y ++ ++ + F ++ +G++
Sbjct: 1194 DVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLL--SDGKFFKMNPNTGELINWVA 1251
Query: 1273 LDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPK----STLFVDVLENM 1328
LD E + + + D G+ P N+T + + + D NDN P FP+ L V VLE
Sbjct: 1252 LDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 1311
Query: 1329 RIGELVSSVTATDSDSGDNADLYYSIT 1355
+ LV++V A D D G+NA++ YS++
Sbjct: 1312 PVNMLVTTVFAKDPDEGNNAEVTYSVS 1338
Score = 355 bits (912), Expect = 5e-97
Identities = 347/1248 (27%), Positives = 546/1248 (43%), Gaps = 146/1248 (11%)
Query: 1998 GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLT 2057
G+++ + LDRE + Y+ V A+ + QV I + DVND+ P F L
Sbjct: 123 GIIRTARRLDRERRDHYSFVA---------ATLLGAVVQVEIRVNDVNDHSPRFPLDSLQ 173
Query: 2058 Y-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLL-------NPLGNKFSI-----GTIDG 2104
+ E +P T A DPD+G S YTL+ +P G F + G +
Sbjct: 174 LDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPGPLPS 233
Query: 2105 -------------EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN 2151
++ L LDREE + + L + A D G+P + V + VLD NDN
Sbjct: 234 PLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNP 293
Query: 2152 PIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGI----VNG--------NTN 2199
P+F Q Y+ + E+ G ++ +V A D D G NG VRY + V G
Sbjct: 294 PVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDA 353
Query: 2200 QEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVP-- 2257
F ++ ++G + V +PLDRE + L V+A D G+ P T VSI +LD+ND P
Sbjct: 354 AYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAI 413
Query: 2258 --VFELSPYSVNVPENLGTLPRTILQVVARDDDRG----------------SNSKLSYVL 2299
+F V E G P + V+ D G + +S L
Sbjct: 414 HVLFLTEGGVARVSE--GARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSL 471
Query: 2300 FGGNEDNAFTLSASGELG-----VTQSLDRETKERFVLMITATDSGSPALTGTGTINVIV 2354
GG D F L G G V LDRE+++ + L++ ATD+GSP L+ T+ + V
Sbjct: 472 EGGEGD--FALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRV 529
Query: 2355 DDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADAS-------------------- 2394
D+ND P F+ + Y ++ E A GT V+ V+ASDAD +
Sbjct: 530 ADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNL 589
Query: 2395 ---KNAVIRIIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTS 2451
++ ++ F I+ +G I T LDRE ++ L VV D G P PLS++
Sbjct: 590 GSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEP-PLSATCL 648
Query: 2452 VLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-----LS 2506
V +TV DVNDN P F Y I G VT +DAD G + YS LS
Sbjct: 649 VSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYSLYDGFLS 708
Query: 2507 GRNSEKFHIDPLRGAIMAAGPLNGASE-VTFS--VHVKDGGSFPKTDSTTVTVRFVNKAD 2563
+ F IDP G I + ++ + T+ V KDGG V + VN
Sbjct: 709 YEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVRVDLEDVNDNH 768
Query: 2564 FPKVRAKEQTFMFPENQPVSSLVTTITGSSLRG--EPMSYYIASGNLGNTFQIDQLTGQV 2621
+ T + E QP + ++ + G ++Y + GN+ + F ID TG +
Sbjct: 769 PVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGII 828
Query: 2622 SISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITV-LDVNDNAPIFKEDPFISEILE 2680
++ PL + + + A+DGG ++ D+T+ + AP E P + ++
Sbjct: 829 YLTLPLSHLESTTLSLMVSAQDGG--GLTAVINADVTIHIFQTTLAPAEFERPKYTFLVY 886
Query: 2681 NLSPR--KILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSH 2738
P I TV A + + + Y I +G++ FSI+ G IR+ +PLD E
Sbjct: 887 EDVPEDSPIGTVKARE-PLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPV 945
Query: 2739 YVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIF-SAHVPENSPLGYTVTRVTTS 2797
VLT++ + GS +S +V I ++D NDN P F + + + +P G +
Sbjct: 946 VVLTVQ-AQLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAE 1004
Query: 2798 DEDIGINAISRYSIMDASL-PFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVST 2856
D D G N + RYSI F I+ + G + ++ L + + + A D G
Sbjct: 1005 DRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQA 1064
Query: 2857 DVTIF--VTDINDNAP--RFSRTSYYLDCPELTEIGSKVTQVFATD-----PDEGSNGQV 2907
+ + V + +++P F Y + E++E S +TQ+ T P ++
Sbjct: 1065 ALLVLTVVIEKREHSPSWTFEHLVYQV---EVSESLSPMTQMLQTQAHPLGPQRAASPLR 1121
Query: 2908 FYFIKS-QSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISE 2966
+ S S F I TG I+ ++ Y+ S N F D ++
Sbjct: 1122 YSLEPSVDSAMFGIRPYTGWIYLRRQFDYE-----STQTYNFRVFAWIPEDGFLQNV--S 1174
Query: 2967 TTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISND 3026
TTV + + D NDN+P FL F V ++ + ++TAI D D G N ++ YF+ +D
Sbjct: 1175 TTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAI-DMDSGKNGQLLYFLLSD 1233
Query: 3027 NHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
FK++ +TG + +L + + +TV D+G+PP ++ V+++VT+ N +
Sbjct: 1234 GKF--FKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNR 1291
Query: 3087 PEFSQ----SHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISS 3130
P F Q + + E + +V TV A+D D N + YS+SS
Sbjct: 1292 PFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSS 1339
Score = 350 bits (899), Expect = 2e-95
Identities = 348/1252 (27%), Positives = 529/1252 (42%), Gaps = 135/1252 (10%)
Query: 736 FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQ 795
F V+ +G+I T LDRE + Y G +Q V I V D D+ P F
Sbjct: 116 FHVHPDTGIIRTARRLDRERRDHYSFVAATLLGAVVQ------VEIRVNDVNDHSPRFPL 169
Query: 796 VAYSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTG-----DQKG-MFAINQVTG- 846
+ V E G A D L S Y + D G F + T
Sbjct: 170 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 229
Query: 847 -----------------QLTTANVIDREEQSFYQLKVVASGG---TVTGDTMVNITVKDL 886
L +DREE + ++L++ A G TG V + V D
Sbjct: 230 PLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDE 289
Query: 887 NDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNP---------- 936
NDN P F Q V E+ Q G + + +A D D G NG V YS++
Sbjct: 290 NDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGA 349
Query: 937 ---KNLFAINEKNGTISLLGPLDVHAGSY-QIEILASDMGVPQLSSSVILTVYVHDVNDN 992
FA+ E +G + + PLD A ++ Q+ + A D G ++V +++ V DVNDN
Sbjct: 350 LGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDN 409
Query: 993 SPVFDQLSYE----VTLSESEPVNSRFFKVQASD------KDSGANGEIAYTIA------ 1036
P L +SE +V SD K+ A GE+ +
Sbjct: 410 RPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISL 469
Query: 1037 --EGNTGDAFGIFPDGQ-----LYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVI 1089
EG GD F + P G L ++ LDRE +D Y L++VA+D PLS + +
Sbjct: 470 SLEGGEGD-FALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLR 528
Query: 1090 LEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQ------ 1143
+ D+ND PLF+ +Y E G+ V VSA D D + + +VQ
Sbjct: 529 VADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCN 588
Query: 1144 ---------------PDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQ 1188
P F + + SG I+ DRE V+A D G P
Sbjct: 589 LGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREV------QEAVELKVVAQDLGEP- 641
Query: 1189 PLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYS 1248
PL V + + D+NDN P F + Y ATI+E A L+V+ASD D G G I YS
Sbjct: 642 PLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYS 701
Query: 1249 IIKG----NEERQFAIDSTSGQVTLIGKLDYEATPA-YSLVIQAVDSGTIPLNSTCTLNI 1303
+ G + F ID GQ+ + +D E PA Y L+++A D G L++ + +
Sbjct: 702 LYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGG--LSAQAFVRV 759
Query: 1304 DILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTF 1363
D+ D NDN P F ST + + + G + +V ATD DSG + Y + N F
Sbjct: 760 DLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLF 819
Query: 1364 SISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPG 1423
+I TG I+L L + L ++A+D G V IH+ P F
Sbjct: 820 TIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERP 879
Query: 1424 DIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAE 1483
+ E++P + + +V A +P + + + Y I G F+I GTI T
Sbjct: 880 KYTFLVYEDVPEDSPIGTVKAREP-LNSSEPIFYR-ISSGDLGGKFSIHPRLGTIRTRKP 937
Query: 1484 IDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI-SQNALAADPSAV 1542
+D E + LTV+A + P + V I V D+NDN P F+ + + + +
Sbjct: 938 LDHETQPVVVLTVQAQLGSAP----ACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTP 993
Query: 1543 IGSVLTTIMAADPDEGANGEIEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIV 1601
G+ L A D D G NG I Y I + F +DR G L + +L Q L +
Sbjct: 994 PGTALYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLTL 1053
Query: 1602 SATDLGPERRKSTTELTIILQGLD-GPVFTQPKYITILKEGEPIG--TNVISIEA--ASP 1656
A D G + + LT++++ + P +T + ++ E + T ++ +A P
Sbjct: 1054 RAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGP 1113
Query: 1657 RGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKST 1716
+ + +P+ Y + E +F I +TG I D E Y V+A
Sbjct: 1114 QRAASPLRYSL-----EPSVDSAMFGIRPYTGWIYLRRQFDYE-STQTYNFRVFAWIPED 1167
Query: 1717 AFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVT 1776
F + V + + D NDN P F D+L L VEE+ I ++TA+D D G N +
Sbjct: 1168 GFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLL 1227
Query: 1777 YTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADD---GLQSSDMRINITVSD 1833
Y ++S F+++P +G+LI LDRE R + + V D +++ M + ++V+D
Sbjct: 1228 YFLLSDG-KFFKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTD 1286
Query: 1834 VNDHTPKFSRPVYSFDIPEDTIPGS----LVAAILATDDDSGVNGEITYIVN 1881
+ND+ P F + + ++ + G LV + A D D G N E+TY V+
Sbjct: 1287 INDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVS 1338
Score = 340 bits (871), Expect = 3e-92
Identities = 353/1262 (27%), Positives = 535/1262 (42%), Gaps = 150/1262 (11%)
Query: 632 FRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYP 691
F + P +G + T LDRE + YS V AT LG+ + ++ + + D+ND+SP F
Sbjct: 116 FHVHPDTGIIRTARRLDRERRDHYSF-VAATLLGA-----VVQVEIRVNDVNDHSPRFPL 169
Query: 692 VQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSI---------SAGDRSRFQVNAQS 742
+ E P G+ A DPD G T Y++ AG + +
Sbjct: 170 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 229
Query: 743 GVISTRMA----------------LDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDT 786
+ S + LDREE A++LQI A DGG + V + VLD
Sbjct: 230 PLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDE 289
Query: 787 QDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGDQKGM------ 838
DNPPVF Q Y V E+ G V V A+ DL N + Y + G
Sbjct: 290 NDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGA 349
Query: 839 ------FAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTM---VNITVKDLNDN 889
FA+ +++G + +DRE Q+++QL V A G + V+I V D+NDN
Sbjct: 350 LGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDN 409
Query: 890 SP--HFLQAIES--VNVVENWQAGHSIFQAKAVDPD------EGVNGMVLYSLKQNPKNL 939
P H L E V E + G + + D D + G + L +L
Sbjct: 410 RPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISL 469
Query: 940 FAINEKNGTISLL-------------GPLDVHAGS-YQIEILASDMGVPQLSSSVILTVY 985
++ G +LL GPLD + Y++ ++A+D G P LS+ L +
Sbjct: 470 -SLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLR 528
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGE--IAYTIAE------ 1037
V D+ND P+F Q Y+ ++SE+ + V ASD D + + YT+ +
Sbjct: 529 VADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCN 588
Query: 1038 -----------GNTGDAFGIFPD-GQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVN 1085
G +F I + G + LDRE+Q+ L VVA D PLSAT
Sbjct: 589 LGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCL 648
Query: 1086 VTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYS------- 1138
V++ ++DVNDN P+F Y E G +V+A D D G G + YS
Sbjct: 649 VSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGFIEYSLYDGFLS 708
Query: 1139 FEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHV 1198
+E Q F + G+I + DRE R A + V A D G L QA V V
Sbjct: 709 YEAPQA-FRIDPHDGQICVSQDIDRE-----RDPATYDLLVEAKDGG---GLSAQAFVRV 759
Query: 1199 YMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQF 1258
++D+NDN P F Y +IS+ T+++ V A+D D G G + Y +I GN F
Sbjct: 760 DLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLF 819
Query: 1259 AIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF--P 1316
IDST+G + L L + + SL++ A D G + + I I F P
Sbjct: 820 TIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERP 879
Query: 1317 KSTLFV--DVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFL 1374
K T V DV E+ IG + + S+ ++Y I+ + G FSI P G+I
Sbjct: 880 KYTFLVYEDVPEDSPIGTVKAREPLNSSEP-----IFYRISSGDLGGKFSIHPRLGTIRT 934
Query: 1375 AKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIP 1434
K LD ETQ + L + A+ G P S+ V I V D NDN P+F I + P
Sbjct: 935 RKPLDHETQPVVVLTVQAQ-LGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTP 993
Query: 1435 IGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFEL 1494
GT++ A D D+ NG + Y+I P F ID G ++ N + L
Sbjct: 994 PGTALYLARAEDRDSGRNGLIRYSIASPQP--GVFAIDRALGVLFLNGSLGAGEQRELTL 1051
Query: 1495 TVKANDQAVPIETRRYALKNVTILVTDLNDNVPMF-----ISQNALAADPSAVIGSVLTT 1549
T++A DQ V + AL +T+++ + ++ P + + Q ++ S + + T
Sbjct: 1052 TLRAEDQGVHPQA---ALLVLTVVI-EKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQ 1107
Query: 1550 IMAADPDEGANGEIEYEIING-DTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSA--TD 1605
P A+ + Y + D+ F + Y+G + + S YN V A +
Sbjct: 1108 AHPLGPQRAAS-PLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPE 1166
Query: 1606 LGPERRKSTTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAA--SPRGSEAPV 1663
G + STT + + D + + E P+ VI A G +
Sbjct: 1167 DGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQL 1226
Query: 1664 EYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQR 1723
Y+++S G+ F + +TG + LDRE + + V ++ + PR
Sbjct: 1227 LYFLLSD-------GKFFKMNPNTGELINWVALDREHRGH-HEMTVLVTDRGSP-PRNAT 1277
Query: 1724 AEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLT----AMDADEGANALVTYTI 1779
V +++ DINDN P FP + + + +G + L A D DEG NA VTY++
Sbjct: 1278 MAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSV 1337
Query: 1780 IS 1781
S
Sbjct: 1338 SS 1339
Score = 330 bits (846), Expect = 2e-89
Identities = 349/1300 (26%), Positives = 555/1300 (42%), Gaps = 154/1300 (11%)
Query: 2059 IPENTPIDTVVFKAQATDPDSGPNSYIEYTLL-----NPLGNKFSIGTIDGEVRLTGELD 2113
+ E P DT+V +A P + + L +PL + F + G +R LD
Sbjct: 73 VDEGLPPDTLVGDIRAGLPAAQQQEGSGFFLSEDSDDSPLLDDFHVHPDTGIIRTARRLD 132
Query: 2114 REEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDI 2173
RE +Y+ V AT L + +V + V D+ND++P F +++++E + GT
Sbjct: 133 RERRDHYSF-VAAT-----LLGAVVQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAF 186
Query: 2174 IQVFAADGDEG---TNG------------------QVRY--------GIVNGNTNQEFRI 2204
A D D G T G Q+RY ++ G+++ +
Sbjct: 187 RLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPL 246
Query: 2205 DSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPY 2264
D + + + LDRE+ + L ++A D G RT +V + +LD ND PVFE Y
Sbjct: 247 D-----LVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEY 301
Query: 2265 SVNVPENLGTLPRTILQVVARDDDRGSNSKLSY------VLFGGNEDNAFTLSA------ 2312
V E+ + +V A D D G N + Y V G+ A +A
Sbjct: 302 RAAVRED-AQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEE 360
Query: 2313 -SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPT----FASK 2367
SG + V + LDRE + L++ A D G+ T +++ V DVNDN P F ++
Sbjct: 361 LSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTE 420
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDAD-----------------ASKNAVIRIIGGNSQFTI 2410
+ E A G V V+ SDAD + + + GG F +
Sbjct: 421 GGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGGEGDFAL 480
Query: 2411 ----NPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRF 2466
P + LDRE++D Y L++V +DAGSP PLS+ ++L+ V D+ND PP F
Sbjct: 481 LPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSP-PLSTEETLLLRVADLNDQPPLF 539
Query: 2467 QHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSE--LHYSL------------------S 2506
Y + PG+ V V+ +DAD + L Y++ +
Sbjct: 540 SQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHT 599
Query: 2507 GRNSEKFHIDPLRGAIMAAGPLNGASE--VTFSVHVKDGGSFP--KTDSTTVTVRFVNKA 2562
F ID GAI L+ + V V +D G P T ++TV VN
Sbjct: 600 AECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDN 659
Query: 2563 DFPKVRAKEQTFMFPENQPVSSLVTTITG----SSLRGEPMSYYIASGNLG----NTFQI 2614
+ P + E+ PV +T S L G + Y + G L F+I
Sbjct: 660 E-PIFWRQVYNATIAEHAPVGHCFLQVTASDADSGLYGF-IEYSLYDGFLSYEAPQAFRI 717
Query: 2615 DQLTGQVSISQPLDFEK-IQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP 2673
D GQ+ +SQ +D E+ Y + +EA+DGG ++ ++D+ DVNDN P+F
Sbjct: 718 DPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVRVDLE--DVNDNHPVFNPST 775
Query: 2674 FISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLD 2732
+++ I + P +I+ V A D+DSG G + YE++ GN+ + F+I+ TG I PL
Sbjct: 776 YVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGIIYLTLPLS 835
Query: 2733 REKVSHYVLTIKSSDKGSPSQSTSVKVMINILD-----ENDNAPRFSQIFSAHVPENSPL 2787
+ + L + + D G + + V I+I P+++ + VPE+SP+
Sbjct: 836 HLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPI 895
Query: 2788 GYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSA 2847
G R + + R S D F+I+P G I +PL+ E + V A
Sbjct: 896 GTVKAREPLNSSE---PIFYRISSGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQA 952
Query: 2848 H--DSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG 2905
+ ST+V I V D+NDN P F RTS + + T G+ + A D D G NG
Sbjct: 953 QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNG 1012
Query: 2906 QVFYFIKS-QSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRH-SFIVTSSDRGKPSL 2963
+ Y I S Q F I+ G +F + G R + + + D+G
Sbjct: 1013 LIRYSIASPQPGVFAIDRALGVLF---------LNGSLGAGEQRELTLTLRAEDQGVHPQ 1063
Query: 2964 ISETTVTINIVDSNDNAPQ--FLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY 3021
+ +T+ +++ +++P F Y V++++ T++++ A S + Y
Sbjct: 1064 AALLVLTV-VIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLGPQRAASPLRY 1122
Query: 3022 FISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSS-QATVHITVT 3080
+ F + TGWI + + Q + V A + L + TV + V
Sbjct: 1123 SLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVW 1182
Query: 3081 EENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
+EN ++P F + + ES ++ ++A D D+ NG + Y + S + F +N
Sbjct: 1183 DENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGK--FFKMN 1240
Query: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVF----LS 3196
+TG L ALD E HEMT+ D G R +V V+V D+NDN P F
Sbjct: 1241 PNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPG 1300
Query: 3197 DDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSS 3236
+ VLE P V + A D D G NA + Y+V S+
Sbjct: 1301 KELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSA 1340
Score = 327 bits (837), Expect = 2e-88
Identities = 337/1330 (25%), Positives = 563/1330 (42%), Gaps = 176/1330 (13%)
Query: 2408 FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQ 2467
F ++P TG I T+ LDRE +D+Y+ V L + V + V DVND+ P
Sbjct: 116 FHVHPDTGIIRTARRLDRERRDHYSFVAATL-------LGAVVQVEIRVNDVNDHSP--- 165
Query: 2468 HHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGP 2527
+F +D L+ + P
Sbjct: 166 --------------------------------------------RFPLDSLQLDVSELSP 181
Query: 2528 LNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVT 2587
A + + H D G F +T V +D PK A F P
Sbjct: 182 PGTAFRLPVA-HDPDAGLF-----STQGYTLVQPSDLPKDPAGP-FFQLRYRTPGPLPSP 234
Query: 2588 TITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFP 2647
+ GSS EP+ + + LD E+ + + IEA DGG P
Sbjct: 235 LLPGSSSPLEPLDLVLL--------------------RRLDREEAAAHRLQIEAWDGGRP 274
Query: 2648 PFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYE 2706
+ +++ VLD NDN P+F++D + + + E+ P ++ V A D+D GPNG + Y
Sbjct: 275 RRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYS 334
Query: 2707 IVNGNMENS------------FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQS 2754
+ + + F++ +G +R RPLDRE + + L +++ D G+ +
Sbjct: 335 VRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEV 394
Query: 2755 TSVKVMINILDENDNAPRFSQIFS-----AHVPENSPLGYTVTRVTTSD-------EDIG 2802
+V+V I +LD NDN P +F A V E + G V RV+ SD ED
Sbjct: 395 ATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEA 454
Query: 2803 INAISRYSIMDASLPFTINPSTGD-------------IVISRPLNREDTDRYRIRVSAHD 2849
+ + D S+ ++ GD + + PL+RE D Y + + A D
Sbjct: 455 TGELG-VGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATD 513
Query: 2850 SGWT-VSTDVTIF--VTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQ 2906
+G +ST+ T+ V D+ND P FS+ Y E G+ V V A+D DE +
Sbjct: 514 AGSPPLSTEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDH 573
Query: 2907 VFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVN----------INRH-----SF 2951
+ ++ G + +K + + F+ + ++R
Sbjct: 574 AW--LRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVEL 631
Query: 2952 IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDK 3011
V + D G+P L + V+I + D NDN P F + Y + ++ VG ++VTA D
Sbjct: 632 KVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTA-SDA 690
Query: 3012 DFGLNSEVEYFISNDNHLG-----KFKLDNDTGWISVASSLISDLNQ-NFFITVTAKDKG 3065
D GL +EY + D L F++D G I V+ + + + + + V AKD G
Sbjct: 691 DSGLYGFIEYSLY-DGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGG 749
Query: 3066 NPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIK 3125
LS+QA V + + + N + P F+ S +I + G+ + V A D+D+ + G +
Sbjct: 750 G--LSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVA 807
Query: 3126 YSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI 3185
Y + GN +F I+S+TGI+ L L + + +SA DGG + VT+++
Sbjct: 808 YELIPGNVSSLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIF 867
Query: 3186 DVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD-SDLFVID 3244
F Y V E+ P + + + A + + + + Y + S D F I
Sbjct: 868 QTTLAPAEFERPKYTFLVYEDVPEDSPIGTVKAREPLNSSEPIF-YRISSGDLGGKFSIH 926
Query: 3245 PNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYY 3304
P G I T+ LD ET+ LTV+A + CS VNI + N+ P F+
Sbjct: 927 PRLGTIRTRKPLDHETQPVVVLTVQA-QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDE 985
Query: 3305 FEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDRE 3364
IS+ P GT + A DRD G +G + Y I + + F I++ G ++++G L
Sbjct: 986 IRISQTTPPGTALYLARAEDRDSGRNGLIRYSI-ASPQPGVFAIDRALGVLFLNGSLGAG 1044
Query: 3365 KEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVT 3424
++ ++L + A++ G A + +TV + + + F +Y V++SE + T +
Sbjct: 1045 EQRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQML 1104
Query: 3425 FVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLA-V 3483
A + S Y + ++ F I P TG I + + D E+ YN V A +
Sbjct: 1105 QTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWI 1164
Query: 3484 DSGTPSATGSASLLVTLEDINDNGP--MLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQ 3541
S +++V + D NDN P + V +V E+ P ++ + + D D N
Sbjct: 1165 PEDGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKN- 1223
Query: 3542 GPFTYYLLSTGPATSYFSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTV 3600
G Y+LLS G +F ++ G L +DRE ++V+ D G P ++T V
Sbjct: 1224 GQLLYFLLSDG---KFFKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAV 1280
Query: 3601 HITVIDQNDN--------PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLT 3652
+++V D NDN P + V++ N+ ++ +V +DPD + + +T
Sbjct: 1281 YVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNM----LVTTVFAKDPD--EGNNAEVT 1334
Query: 3653 SGVTSLFSIP 3662
V+S +P
Sbjct: 1335 YSVSSARPMP 1344
Score = 323 bits (829), Expect = 2e-87
Identities = 286/1034 (27%), Positives = 449/1034 (43%), Gaps = 75/1034 (7%)
Query: 79 ALFAINSSTGALYTTSTIDRESLPSD--VINLVVLSSAPTYPT-EVRVLVRDLNDNAP-- 133
A FA+ +G + +DRE+ V+ + P T V + V D+NDN P
Sbjct: 354 AYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAI 413
Query: 134 --VFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRL---- 187
+F V E + G V + +D+D D + + G G L
Sbjct: 414 HVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEG 473
Query: 188 ---DITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDIN 244
D L P G L +G LDRE Y+LL+ D G P + + V D+N
Sbjct: 474 GEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLN 533
Query: 245 DNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEG--TNADIRYRLQDEGTP------- 295
D PP+F HY+A V E A G+ V+ V+A+DADE +A +RY + P
Sbjct: 534 DQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQ 593
Query: 296 ------------FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQL 343
F +D E+G I+ LD E + L V A D G P L+ I +
Sbjct: 594 SKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITV 653
Query: 344 LDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNE 403
DVNDN+P+ + + AT + E+A VG +T +DADS G I + G
Sbjct: 654 DDVNDNEPIFWRQVYNAT-----IAEHAPVGHCFLQVTASDADS-GLYGFIEYSLYDGFL 707
Query: 404 QRHFEVQSSKVPNLSLIKVASALDRERIPS-YNLTVSVSDNYGAPPGAAVQARSSVASLV 462
P+ I V+ +DRER P+ Y+L V D G A V+
Sbjct: 708 SYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVR--------- 758
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGW 522
+ + D+ND+ PVF+ Y ++S+E PG+ + + ATD DSG+ + Y ++ GN
Sbjct: 759 VDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSL 818
Query: 523 FHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVF 582
F I +G++ L ++ + L +SA+D G V A + + + F
Sbjct: 819 FTIDSTTGIIYLTLP--LSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEF 876
Query: 583 SQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLS 642
+P+ Y V E+ P + + ++A + L + + + + + + F + P G +
Sbjct: 877 ERPK-YTFLVYEDVPEDSPIGTVKARE-PLNSSEPIFYRISSGDLGGK-FSIHPRLGTIR 933
Query: 643 TISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENE 702
T LD E Q L V A LGS P S +N++++D+NDN P F I +
Sbjct: 934 TRKPLDHETQPVVVLTVQA-QLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTT 992
Query: 703 PGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQ 762
P G+ + A D D G NG ++YSI++ F ++ GV+ +L E+ L
Sbjct: 993 PPGTALYLARAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLT 1052
Query: 763 IVATDGGNLQSPNQAIVTITV-LDTQDNPP--VFSQVAYSFVVFENVALGYHVGSVSAST 819
+ A D G P A++ +TV ++ +++ P F + Y V E+++ + A
Sbjct: 1053 LRAEDQG--VHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHP 1110
Query: 820 MDLN---SNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA----SGGT 872
+ S + Y + MF I TG + D E Y +V A G
Sbjct: 1111 LGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPEDGFL 1170
Query: 873 VTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSL 932
T V + V D NDNSP FL + + V E+ I + A+D D G NG +LY L
Sbjct: 1171 QNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFL 1230
Query: 933 KQNPKNLFAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVND 991
+ K F +N G + LD H G +++ +L +D G P ++++ + V V D+ND
Sbjct: 1231 LSDGK-FFKMNPNTGELINWVALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDIND 1289
Query: 992 NSPVFDQL----SYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIF 1047
N P F Q V + E +PVN V A D D G N E+ Y+++ G
Sbjct: 1290 NRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSVSSARPMPLKGKT 1349
Query: 1048 PDGQLYIKSELDRE 1061
G+ K + +++
Sbjct: 1350 AFGKQSCKKQTNKQ 1363
Score = 283 bits (723), Expect = 4e-75
Identities = 285/1065 (26%), Positives = 463/1065 (43%), Gaps = 126/1065 (11%)
Query: 2637 VWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKD 2696
VW+ A G SS + ++T L V++ P D + +I L A +
Sbjct: 54 VWLWAASG-----SSAQLFNLT-LSVDEGLP---PDTLVGDIRAGLP--------AAQQQ 96
Query: 2697 SGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTS 2756
G L + + + + F ++ TG IR+ R LDRE+ HY S +
Sbjct: 97 EGSGFFLSEDSDDSPLLDDFHVHPDTGIIRTARRLDRERRDHY------SFVAATLLGAV 150
Query: 2757 VKVMINILDENDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDAS 2815
V+V I + D ND++PRF V E SP G D D G+ + Y+++ S
Sbjct: 151 VQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPS 210
Query: 2816 --------------------LPFTINPSTG------DIVISRPLNREDTDRYRIRVSAHD 2849
LP + P + D+V+ R L+RE+ +R+++ A D
Sbjct: 211 DLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWD 270
Query: 2850 SGWTVST---DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQ 2906
G T V + V D NDN P F + Y E + G++V +V ATD D G NG
Sbjct: 271 GGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGF 330
Query: 2907 VFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNV--NINR-----HSFIVTSSDRG 2959
V Y ++++ + + G + + + ++G V ++R H +V + D G
Sbjct: 331 VRYSVRAR-QVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGG 389
Query: 2960 KPSLISETTVTINIVDSNDNAPQ----FLKSKYFTPVTKNVKVGTKLIRVTAID-DKDFG 3014
++ V+I ++D NDN P FL V++ + G + RV+ D D D+
Sbjct: 390 AEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWE 449
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTG---------------WISVASSLISDLNQNFFITV 3059
E + G L + G ++ V L + + + +
Sbjct: 450 KEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLL 509
Query: 3060 TAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAA 3119
A D G+PPLS++ T+ + V + N P FSQ H A++ E+ + G++V VSA D D A
Sbjct: 510 VATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEA 569
Query: 3120 -------------------MNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKH 3160
+ L + + FAI+S +G ++ + LD E+ +
Sbjct: 570 GSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAV 629
Query: 3161 EMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATD 3220
E+ + A D G + C V++ V DVNDN P+F Y T+ E+AP G + + A+D
Sbjct: 630 ELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASD 689
Query: 3221 ADSGTNAVIAYTVQS-----SDSDLFVIDPNTGVITTQGFLDFE-TKQSYHLTVKAFNVP 3274
ADSG I Y++ F IDP+ G I +D E +Y L V+A +
Sbjct: 690 ADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGG 749
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVH 3334
+F V + L+ N+ P F Y IS+ GT + V A+D+D G G V
Sbjct: 750 GLSAQAF--VRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVA 807
Query: 3335 YLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNV- 3393
Y + + F I+ TG IY++ L + +SL V A++ G + +VT+++
Sbjct: 808 YELIPGNVSSLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIF 867
Query: 3394 --TVLDAN-DPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNEN 3450
T+ A + P +T +Y + E PIGT V A + + S Y I SG+
Sbjct: 868 QTTLAPAEFERPKYTFLVYE-DVPEDSPIGT----VKA--REPLNSSEPIFYRISSGDLG 920
Query: 3451 GAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP-- 3508
G FSI+P+ G I LD ET P+ L+V A G+ A S + +T+ D+NDN P
Sbjct: 921 GKFSIHPRLGTIRTRKPLDHETQPVVVLTVQA-QLGSAPACSSTEVNITVMDVNDNHPAF 979
Query: 3509 MLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTA-GVLS 3567
+ T E + + PGT + ++ D D N G Y + S P F++ A GVL
Sbjct: 980 LRTSDEIRISQTTPPGTALYLARAEDRDSGRN-GLIRYSIAS--PQPGVFAIDRALGVLF 1036
Query: 3568 TTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPS 3612
+ + + L++ +D GV ++ + + + + +PS
Sbjct: 1037 LNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPS 1081
Score = 266 bits (680), Expect = 4e-70
Identities = 338/1309 (25%), Positives = 526/1309 (40%), Gaps = 143/1309 (10%)
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQL 1455
G + S + +++HV + + S ++ S+ E +P T V + A P A
Sbjct: 40 GARTQRSLLWLLVHVWLWAASGSSAQLFNLTLSVDEGLPPDTLVGDIRAGLPAAQQQEGS 99
Query: 1456 SYTIIQQM---PRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYAL 1512
+ + + P + F + G I T +DRE + + T A+
Sbjct: 100 GFFLSEDSDDSPLLDDFHVHPDTGIIRTARRLDRERRDHYSFVAA---------TLLGAV 150
Query: 1513 KNVTILVTDLNDNVPMFISQNALAADPSAVI--GSVLTTIMAADPDEGANGEIEYEII-- 1568
V I V D+ND+ P F ++L D S + G+ +A DPD G Y ++
Sbjct: 151 VQVEIRVNDVNDHSPRF-PLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQP 209
Query: 1569 ----NGDTDTFIVDRYSGDLRVASALVPSQ--------------------LIYNLIVSAT 1604
F RY + S L+P + L + A
Sbjct: 210 SDLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAW 269
Query: 1605 DLGPERRKS--TTELTIILQGLDGPVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEA 1661
D G RR + EL ++ + + PVF Q +Y ++E G V + A G
Sbjct: 270 DGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNG 329
Query: 1662 PVEYYIVSVRCEEKTVG-------RLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEK 1714
V Y + + + G F + +G+++ LDRE A L V
Sbjct: 330 FVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQL--VVEARD 387
Query: 1715 STAFPRTQRAEVEITLQDINDNPP----VFPTDMLDLTVEENIGDGSKIMQLTAMDAD-- 1768
A P V I + D+NDN P +F T+ V E G + +++ DAD
Sbjct: 388 GGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGD 447
Query: 1769 -EGANALVTYTIISGADDSFRIDPESGD---------------LIATRRLDRERRSKYSL 1812
E + + D S + E G+ L LDRE R Y L
Sbjct: 448 WEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYEL 507
Query: 1813 LVRADDGLQ---SSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDD 1869
L+ A D S++ + + V+D+ND P FS+ Y + E PG++V + A+D D
Sbjct: 508 LLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDAD 567
Query: 1870 SGVNGEI-------------------TYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQ 1910
+ + +V+ + F ++ +G + R LD EVQ+
Sbjct: 568 EAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQE 627
Query: 1911 YYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNV 1968
L V A+D G T V + DVNDN PIF Y+ ++ E+ PVG L
Sbjct: 628 AVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTA 687
Query: 1969 TDADDGINSQLTYSIASG----DSLGQFTVD-KNGVLKVLKALDRE-SQSFYNLVVQVHD 2022
+DAD G+ + YS+ G ++ F +D +G + V + +DRE + Y+L+V+ D
Sbjct: 688 SDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKD 747
Query: 2023 LPQIPASRFTSTAQVSIILLDVNDNPPTF-LSPKLTYIPENTPIDTVVFKAQATDPDSGP 2081
+ A F V + L DVNDN P F S +T I + T T + ATD DSG
Sbjct: 748 GGGLSAQAF-----VRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGI 802
Query: 2082 NSYIEYTLLNPLGNKFSIGTID---GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSST 2138
+ Y L+ GN S+ TID G + LT L E + +L V A D G + +
Sbjct: 803 YGTVAYELIP--GNVSSLFTIDSTTGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINA 860
Query: 2139 EVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNT 2198
+V + + F + Y + E+ + I V A + ++ + Y I +G+
Sbjct: 861 DVTIHIFQTTLAPAEFERPKYTFLVYEDVPEDSPIGTVKARE-PLNSSEPIFYRISSGDL 919
Query: 2199 NQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPV 2258
+F I G I KPLD E P LTVQA GS P ++ V+I ++D+ND P
Sbjct: 920 GGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQA-QLGSAPACSSTEVNITVMDVNDNHPA 978
Query: 2259 FELSPYSVNVPENLGTLPRTILQVV-ARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGEL 2316
F + + + + T P T L + A D D G N + Y + + F + A G L
Sbjct: 979 FLRTSDEIRISQT--TPPGTALYLARAEDRDSGRNGLIRYSI-ASPQPGVFAIDRALGVL 1035
Query: 2317 GVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVP--TFASKAYFTTIP 2374
+ SL + L + A D G + V+++ ++ P TF Y +
Sbjct: 1036 FLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEK-REHSPSWTFEHLVYQVEVS 1094
Query: 2375 EDAPTGTDVLLVNASDADASKNA-----VIRIIGGNSQFTINPSTGQIITSALLDRETKD 2429
E T +L A + A + ++ F I P TG I D E+
Sbjct: 1095 ESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQ 1154
Query: 2430 NYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVT 2489
Y V + ST+V+V V D NDN P F H + +P + +T
Sbjct: 1155 TYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKIT 1214
Query: 2490 VTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLN----GASEVTFSVHVKDGGS 2545
D D G N +L Y L + + F ++P G ++ L+ G E+T V V D GS
Sbjct: 1215 AIDMDSGKNGQLLYFLLS-DGKFFKMNPNTGELINWVALDREHRGHHEMT--VLVTDRGS 1271
Query: 2546 FPKTDSTTVTVRFV----NKADFPK-VRAKEQTFMFPENQPVSSLVTTI 2589
P+ + V V N+ FP+ + KE E QPV+ LVTT+
Sbjct: 1272 PPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTV 1320
Score = 176 bits (447), Expect = 4e-43
Identities = 187/670 (27%), Positives = 284/670 (42%), Gaps = 55/670 (8%)
Query: 76 ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTE--VRVLVRDLNDNAP 133
E+ F I+ G + + IDRE P+ LV + VRV + D+NDN P
Sbjct: 710 EAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGGGLSAQAFVRVDLEDVNDNHP 769
Query: 134 VFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLNP 193
VF + V + +++ G ++I ATD D G G +Y +I GN + F +D T
Sbjct: 770 VFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTV--AYELIPGNVSSLFTIDSTTG- 826
Query: 194 SGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSS 253
++L L + L+V +D G V + + P F
Sbjct: 827 -----IIYLTLP--LSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERP 879
Query: 254 HYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQ--DEGTPFQMDPETGLITVREPL 311
Y V ED S + V A + ++ I YR+ D G F + P G I R+PL
Sbjct: 880 KYTFLVYEDVPEDSPIGTVKAREP-LNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPL 938
Query: 312 DFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENA 371
D E + LTVQA P+ + E I ++DVNDN P F TS + +
Sbjct: 939 DHETQPVVVLTVQAQLGSAPACSS-TEVNITVMDVNDNHPA-----FLRTSDEIRISQTT 992
Query: 372 QVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERI 431
GT + L D DS NG I I + F + + L ++ + +L
Sbjct: 993 PPGTALYLARAEDRDS-GRNGLIRYSI-ASPQPGVFAIDRA----LGVLFLNGSLGAGEQ 1046
Query: 432 PSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPP--VFSQQVYRVNLSEEAP 489
LT+ D G QA V ++VI + +H P F VY+V +SE
Sbjct: 1047 RELTLTLRAEDQ-----GVHPQAALLVLTVVI---EKREHSPSWTFEHLVYQVEVSESLS 1098
Query: 490 PGSYVSGISATD-GDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQI 548
P + + A G + LRYS+ F I ++G + +
Sbjct: 1099 PMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNF 1158
Query: 549 VLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSV--VENAPTGTELL-ML 605
+ + G VS ++V + D ND P F +DV VE +P ++ +
Sbjct: 1159 RVFAWIPEDGFLQNVS-TTVIVRVWDENDNSPTFL----HDVLFLKVEESPVPQGVIGKI 1213
Query: 606 RATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L +D + F+++P +G L +LDRE + + + VL TD G
Sbjct: 1214 TAIDMDSGKNGQLLYFLL---SDGKFFKMNPNTGELINWVALDREHRGHHEMTVLVTDRG 1270
Query: 666 SPPQSSMARINVSLLDINDNSPVFYPV-----QYFAHIKENEPGGSYITTVSATDPDLGT 720
SPP+++ + VS+ DINDN P F+P + + E +P +TTV A DPD G
Sbjct: 1271 SPPRNATMAVYVSVTDINDNRP-FFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGN 1329
Query: 721 NGTVKYSISA 730
N V YS+S+
Sbjct: 1330 NAEVTYSVSS 1339
Score = 175 bits (444), Expect = 9e-43
Identities = 208/777 (26%), Positives = 315/777 (40%), Gaps = 113/777 (14%)
Query: 3021 YFISNDNH----LGKFKLDNDTGWISVASSLISDLNQNF-FITVTAKDKGNPPLSSQATV 3075
+F+S D+ L F + DTG I A L + ++ F+ T L + V
Sbjct: 101 FFLSEDSDDSPLLDDFHVHPDTGIIRTARRLDRERRDHYSFVAATL-------LGAVVQV 153
Query: 3076 HITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSI------- 3128
I V + N H+P F + + E G+ R A D DA + Y++
Sbjct: 154 EIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLP 213
Query: 3129 -------------SSGNEEGIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGW 3171
+ G SS+ + L L + LD E H + I A DGG
Sbjct: 214 KDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGR 273
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAY 3231
RTG SV + V+D NDN PVF D+Y V E+A G V + ATD D G N + Y
Sbjct: 274 PRRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRY 333
Query: 3232 TVQS-------------SDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEER 3278
+V++ D+ F ++ +GV+ LD E + + L V+A + E
Sbjct: 334 SVRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPE 393
Query: 3279 CSFATVNIQLKGTNEYVPR----FVSKLYYFEISEAAPKGTIVGEVFASDRD-------- 3326
+ V+I + N+ P F+++ +SE A G V V SD D
Sbjct: 394 VATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDE 453
Query: 3327 ----LGT---DGEVHYLIFGNSRKKGFQINKKTGQIY--VSGILDREKEERVSLKVLAKN 3377
LG DG + + G G + V G LDRE + L ++A +
Sbjct: 454 ATGELGVGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATD 513
Query: 3378 FGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPS 3436
GS + E T+ + V D ND PP+F+ Y +SE GT V +VSA D+D S
Sbjct: 514 AGSPPLS--TEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGS 571
Query: 3437 ---WSRF---------------SYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNL 3478
W R+ S + + +F+I+ ++G I+ LDRE L
Sbjct: 572 DHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVEL 631
Query: 3479 SVLAVDSGTPSATGSASLLVTLEDINDNGPML--TVSEGEVMENKRPGTLVMTLQSTDPD 3536
V+A D G P + + + +T++D+NDN P+ V + E+ G + + ++D D
Sbjct: 632 KVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQVTASDAD 691
Query: 3537 LPPNQGPFTYYLLSTG----PATSYFSLST-AGVLSTTREIDREQ-IADFYLSVVTKDSG 3590
F Y L G A F + G + +++IDRE+ A + L V KD G
Sbjct: 692 --SGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGG 749
Query: 3591 VPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSV--KPQDPDVLDSFH 3648
+S+ V + + D NDN + PG + +V QD + +
Sbjct: 750 --GLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVA 807
Query: 3649 CSLTSG-VTSLFSIPGGTCDLN-----SQPRSTDGTFDLTVLSNDGVHSTVTSNIRV 3699
L G V+SLF+I T + S ST T L V + DG T N V
Sbjct: 808 YELIPGNVSSLFTIDSTTGIIYLTLPLSHLEST--TLSLMVSAQDGGGLTAVINADV 862
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 354 bits (908), Expect = 1e-96
Identities = 263/805 (32%), Positives = 414/805 (51%), Gaps = 67/805 (8%)
Query: 25 LRVFWLLSLLPGQAWVHGAEPRQ-VFQVLEEQPPGTLVGTIQ-------------TRPGF 70
LR F+LL+ L + A ++ ++ + EE P +G I T
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 71 TYRLSESHA---LFAINSSTGALYTTST-IDRESLPSDV-----------INLVVLSSAP 115
YRL L ++SSTG ++TTS IDRE L + + +V+L +
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDF 122
Query: 116 TYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYR 175
+++++V+D NDNAP+FP P I ++ E++ + + +ATD D G NGV H Y
Sbjct: 123 FRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQH--YE 180
Query: 176 IIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQ 235
++ G F LDI P GE + L+ + LDRE Y + ++VED G P++
Sbjct: 181 LLNGQSV--FGLDIVETPEGE-KWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAI 237
Query: 236 VNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP 295
+ VTV D+NDN PVF + +PE+A VG+SV+Q+ A DAD G+NA+IRY + P
Sbjct: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
Query: 296 -----FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDND 350
F ++ TGLITV+ LD E + +TV A D S RA I + DVNDN
Sbjct: 298 ATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGS--STPARATVTINVTDVNDNP 355
Query: 351 PVVKFRY-FPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
P + RY + + E V T +AL+TV+D D+ NG + I + F +
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD-VNGKVICFI---EREVPFHL 411
Query: 410 QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIN 469
+ + N L++ +S LD E ++ + SD+ G P + + A + + + D N
Sbjct: 412 K-AVYDNQYLLETSSLLDYEGTKEFSFKIVASDS-GKP------SLNQTALVRVKLEDEN 463
Query: 470 DHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHS 529
D+PP+F+Q V +++SE G Y++ ISATD DSG NA++ Y + G +F + +
Sbjct: 464 DNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKT 521
Query: 530 GLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYD 589
G++T +S DRE + + ++ARD G P S A ++VT+LD ND P F+ +
Sbjct: 522 GVLT--ASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH-NHFQ 578
Query: 590 VSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDR 649
V EN P + + ++ TD D G+N V S+ D +F LDP SG + + S DR
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSIL---NDNDNFVLDPYSGVIKSNVSFDR 635
Query: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPV---QYFAHIKENEPGGS 706
E+Q+ Y+ V ATD G PP+SS A++ ++++D+NDNSPV F + + GS
Sbjct: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
Query: 707 YITTVSATDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVA 765
+ V A D D G N +KY+I +G ++ F+++ +G I+ + ++L +
Sbjct: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
Query: 766 TDGGNLQSPNQ-AIVTITVLDTQDN 789
+D G +S + +V + V DT N
Sbjct: 756 SDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 306 bits (783), Expect = 4e-82
Identities = 236/739 (31%), Positives = 352/739 (47%), Gaps = 51/739 (6%)
Query: 804 ENVALG-----YHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQL-TTANVIDRE 857
ENV +G ++ ++A+T S + L++ + ++ TG++ TT+N IDRE
Sbjct: 36 ENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDRE 95
Query: 858 E-----------QSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENW 906
+ + F++L+VV + I VKD NDN+P F + ++++ EN
Sbjct: 96 KLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT 155
Query: 907 QAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAIN-------EKNGTISLLGPLD-VH 958
A DPD G NG+ Y L N +++F ++ EK + + LD
Sbjct: 156 LINSRFPIPSATDPDTGFNGVQHYELL-NGQSVFGLDIVETPEGEKWPQLIVQQNLDREQ 214
Query: 959 AGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKV 1018
+Y ++I D G PQ SS+ IL V V DVNDN PVF + EV + E+ PV + ++
Sbjct: 215 KDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQL 274
Query: 1019 QASDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASD 1074
A+D D G+N EI Y +F G + ++ LDRE + + V+ASD
Sbjct: 275 HATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
Query: 1075 RAVEPLSATVNVTVILEDVNDNRP------LFNSTNYTFYFEEEQRAGSFVGKVSAVDKD 1128
+ P ATV + V DVNDN P + + N T Y E+ + + ++ DKD
Sbjct: 335 GSSTPARATVTINV--TDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD 392
Query: 1129 FGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQ 1188
NG+V E P F L A+ N + + SL+ GT FSF ++A+D G P
Sbjct: 393 TDVNGKVICFIEREVP-FHLKAV---YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPS 448
Query: 1189 PLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYS 1248
L A V V ++D NDN P F + + ++SE+ + +SA+D D G N I Y
Sbjct: 449 -LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
Query: 1249 IIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDE 1308
+ G F +D +G +T D E + + A D+GT PL S + + +LDE
Sbjct: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
Query: 1309 NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN 1368
NDN+P F + V EN+ V +T TD+D+G+N + SI N++ F + P
Sbjct: 566 NDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSI--LNDNDNFVLDPY 623
Query: 1369 TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPP---SFPPGDI 1425
+G I D E QS Y ++ A D G+PPRSST V I+V D NDN P S P
Sbjct: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
Query: 1426 FKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEID 1485
FK + + G+ V V A D D +N +L YTI+ +G F ID V G I +
Sbjct: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKG-LFRIDPVTGNITLEEKPA 742
Query: 1486 REFANLFELTVKANDQAVP 1504
L L V +D P
Sbjct: 743 PTDVGLHRLVVNISDLGYP 761
Score = 299 bits (765), Expect = 5e-80
Identities = 214/671 (31%), Positives = 334/671 (49%), Gaps = 58/671 (8%)
Query: 982 LTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTG 1041
+ + V D NDN+P+F +++ E+ +NSRF A+D D+G NG Y + G +
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS- 186
Query: 1042 DAFGI----FPDG----QLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDV 1093
FG+ P+G QL ++ LDRE +D YV+ + D S+T + V + DV
Sbjct: 187 -VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 1094 NDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF-EMVQPD----FEL 1148
NDNRP+F + E G+ V ++ A D D G N E+RY F V P F L
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 1149 HAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAP 1208
+ +G IT DRE TA+ TV+A+D G P + ATV + + D+NDN P
Sbjct: 306 NNTTGLITVQRSLDREE------TAIHKVTVLASD-GSSTPAR--ATVTINVTDVNDNPP 356
Query: 1209 ----KFLKDFYQATI--SESAANLTQVLRVSASDVDEGNNGLIHYSI-------IKGNEE 1255
+++ T+ SE T++ ++ SD D NG + I +K +
Sbjct: 357 NIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD 416
Query: 1256 RQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF 1315
Q+ ++++S LDYE T +S I A DSG LN T + + + DENDN P F
Sbjct: 417 NQYLLETSS-------LLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIF 469
Query: 1316 PKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLA 1375
+ + + V EN R G +++++ATD DSG NAD+ Y + N F + TG + +
Sbjct: 470 NQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKTGVLTAS 527
Query: 1376 KKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI 1435
+ D E Q + +TA+D G PP S +V++ V D NDN P F + EN+P
Sbjct: 528 RVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK 587
Query: 1436 GTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELT 1495
++V +T D DA N ++ +I+ ++F +D G I +N DRE + +
Sbjct: 588 YSTVGVITVTDADAGENKAVTLSILND---NDNFVLDPYSGVIKSNVSFDREQQSSYTFD 644
Query: 1496 VKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAA----DPSAVIGSVLTTIM 1551
VKA D P R + VTI V D+NDN P+ IS + + SA+ GSV+ +
Sbjct: 645 VKATDGGQP---PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVF 701
Query: 1552 AADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASALVPSQL-IYNLIVSATDLGPE 1609
A D D G N E++Y I++G+ F +D +G++ + P+ + ++ L+V+ +DLG
Sbjct: 702 AVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
Query: 1610 RRKSTTELTII 1620
+ T L +
Sbjct: 762 KSLHTLVLVFL 772
Score = 295 bits (755), Expect = 8e-79
Identities = 223/718 (31%), Positives = 352/718 (49%), Gaps = 55/718 (7%)
Query: 2577 PENQPVSSL-----VTTITGSSLRGEPMSYYIASGNLGNT--FQIDQLTGQV-SISQPLD 2628
PEN P+ ++ ++ I ++ + Y + S G+ ++ TG++ + S +D
Sbjct: 35 PENVPIGNIPKDLNISHINAATGTSASLVYRLVS-KAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 2629 FEKIQKYVVWIEARDGGFP--------PFSSYEKLDITVLDVNDNAPIFKEDPFISEILE 2680
EK+ + E + F F K+ I V D NDNAP+F I E
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPE 153
Query: 2681 N-LSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSI-----NHATGEIRSVRPLDRE 2734
N L + SA D D+G NG YE++NG I ++ + LDRE
Sbjct: 154 NTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDRE 213
Query: 2735 KVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTR 2793
+ YV+ IK D G+P +S++ + + + D NDN P F + H+PEN+P+G +V +
Sbjct: 214 QKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQ 273
Query: 2794 VTTSDEDIGINAISRYSIMDASLP-----FTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+ +D DIG NA RY P F +N +TG I + R L+RE+T +++ V A
Sbjct: 274 LHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLAS 333
Query: 2849 DSGWTVS-TDVTIFVTDINDNAPRFSRTSYYLDCP--------ELTEIGSKVTQVFATDP 2899
D T + VTI VTD+NDN P Y+ P E + +K+ + +D
Sbjct: 334 DGSSTPARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDK 391
Query: 2900 DEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRG 2959
D NG+V FI+ + F + A N+ +L+ ++ + SF + +SD G
Sbjct: 392 DTDVNGKVICFIEREVP-FHLKAVYD---NQYLLETSSLLDYEGTK--EFSFKIVASDSG 445
Query: 2960 KPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEV 3019
KPSL V + + D NDN P F + V++N + G L ++A D+ D G N+++
Sbjct: 446 KPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDE-DSGKNADI 504
Query: 3020 EYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITV 3079
Y + + F LD TG ++ + + + F TVTA+D G PPL SQA V +TV
Sbjct: 505 VYQLGPNASF--FDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTV 562
Query: 3080 TEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAI 3139
+EN ++P+F+ +H + E+ S V ++ D DA N + SI + N+ F +
Sbjct: 563 LDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN--FVL 620
Query: 3140 NSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFL---S 3196
+ +G++ + D E + + A DGG R+ VT+NV+DVNDNSPV + S
Sbjct: 621 DPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS 680
Query: 3197 DDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQ 3253
+ F V +A G+ V + A D D+G NA + YT+ S ++ LF IDP TG IT +
Sbjct: 681 NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
Score = 294 bits (753), Expect = 1e-78
Identities = 239/766 (31%), Positives = 362/766 (47%), Gaps = 66/766 (8%)
Query: 698 IKENEPGGSYIT--TVSATDPDLGTNGTVKYSI--SAGDRSRFQVNAQSG-VISTRMALD 752
+ EN P G+ +S + GT+ ++ Y + AGD +V++ +G + +T +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 753 REEKTA-----------YQLQIVATDGGNLQSPNQAI----VTITVLDTQDNPPVFSQVA 797
RE+ A ++L++V PN + I V DT DN P+F
Sbjct: 94 REKLCAGASYAEENECFFELEVVIL-------PNDFFRLIKIKIIVKDTNDNAPMFPSPV 146
Query: 798 YSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQK-GMFAINQVTG----QLTT 850
+ + EN + SA+ D N Y + G G+ + G QL
Sbjct: 147 INISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIV 206
Query: 851 ANVIDREEQSFYQLKV-VASGGT--VTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQ 907
+DRE++ Y +K+ V GGT + ++ +TV D+NDN P F + V++ EN
Sbjct: 207 QQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
Query: 908 AGHSIFQAKAVDPDEGVNGMVLY----SLKQNPKNLFAINEKNGTISLLGPLD-VHAGSY 962
G S+ Q A D D G N + Y + K LFA+N G I++ LD +
Sbjct: 267 VGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIH 326
Query: 963 QIEILASDMGVPQLSSSVILTVYVHDVNDNSP------VFDQLSYEVTLSESEPVNSRFF 1016
++ +LASD ++V T+ V DVNDN P + ++ V LSE +PVN++
Sbjct: 327 KVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIA 384
Query: 1017 KVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ--LYIKSELDRELQDRYVLMVVASD 1074
+ SDKD+ NG++ I ++ D Q L S LD E + +VASD
Sbjct: 385 LITVSDKDTDVNGKVICFIEREVPFHLKAVY-DNQYLLETSSLLDYEGTKEFSFKIVASD 443
Query: 1075 RAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGE 1134
L+ T V V LED NDN P+FN E R G ++ +SA D+D G N +
Sbjct: 444 SGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD 503
Query: 1135 VRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQA 1194
+ Y F+L +G +T + FDRE R F FTV A D G P PL+ QA
Sbjct: 504 IVYQLGPNASFFDLDRKTGVLTASRVFDREEQER------FIFTVTARDNGTP-PLQSQA 556
Query: 1195 TVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE 1254
V V + D NDN+PKF + +Q +SE+ + V ++ +D D G N + SI+ N+
Sbjct: 557 AVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND 616
Query: 1255 ERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTP- 1313
F +D SG + D E +Y+ ++A D G P +ST + I+++D NDN+P
Sbjct: 617 --NFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPV 674
Query: 1314 --SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGS 1371
S P +T F V + G +V+ V A D D+G NA+L Y+I NN G F I P TG+
Sbjct: 675 VISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
Query: 1372 IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVV-IHVRDFNDN 1416
I L +K L++L + D G P T+ +V ++V D N
Sbjct: 735 ITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 286 bits (732), Expect = 4e-76
Identities = 232/760 (30%), Positives = 363/760 (47%), Gaps = 61/760 (8%)
Query: 1953 LMENLPVGSTVLVFNVT--DADDGINSQLTYSIAS--GDS-LGQFTVDKNGVLKVLKALD 2007
L EN+P+G+ N++ +A G ++ L Y + S GD+ L + + + +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 2008 RE-----------SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL 2056
RE ++ F+ L V + LP + F ++ II+ D NDN P F SP +
Sbjct: 94 REKLCAGASYAEENECFFELEVVI--LP----NDFFRLIKIKIIVKDTNDNAPMFPSPVI 147
Query: 2057 TY-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKFSIGTIDGE----VRLT 2109
IPENT I++ ATDPD+G N Y LLN + + T +GE + +
Sbjct: 148 NISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQ 207
Query: 2110 GELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLT 2169
LDRE+ Y + + D G P SS+ + V V D+NDN P+F + +V I EN
Sbjct: 208 QNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
Query: 2170 GTDIIQVFAADGDEGTNGQVRY---GIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYH 2226
GT +IQ+ A D D G+N ++RY V T + F +++ TG ITV + LDRE+T +
Sbjct: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
Query: 2227 LTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL----SPYSVNV-PENLGTLPRTILQ 2281
+TV A+D STP T T+++ D+ND P +L SP + V + I
Sbjct: 328 VTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIAL 385
Query: 2282 VVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE----LGVTQSLDRETKERFVLMITAT 2337
+ D D N K+ + + F L A + L + LD E + F I A+
Sbjct: 386 ITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 2338 DSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA 2397
DSG P+L T + V ++D NDN P F ++ E+ G + ++A+D D+ KNA
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 2398 -VIRIIGGN-SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
++ +G N S F ++ TG + S + DRE ++ + V D G+P PL S +V+VT
Sbjct: 503 DIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTP-PLQSQAAVIVT 561
Query: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHI 2515
V D NDN P+F H+ + + S V +TVTDAD G N + S+ N + F +
Sbjct: 562 VLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDN-DNFVL 620
Query: 2516 DPLRGAIMA--AGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQT 2573
DP G I + + S TF V DGG P++ + VT+ ++ D V +
Sbjct: 621 DPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS 680
Query: 2574 FMFPENQPVSSL-------VTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQP 2626
+ P+S++ V + + + Y I SGN F+ID +TG +++ +
Sbjct: 681 NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEK 740
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNA 2666
+ + + + D G+P S L + L VND A
Sbjct: 741 PAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVNDTA 778
Score = 281 bits (718), Expect = 1e-74
Identities = 221/757 (29%), Positives = 351/757 (46%), Gaps = 63/757 (8%)
Query: 1753 IGDGSKIMQLTAMDADEGANALVTYTIISGADDS--FRIDPESGDLIAT-RRLDRERRSK 1809
IG+ K + ++ ++A G +A + Y ++S A D+ ++ +G++ T R+DRE+
Sbjct: 40 IGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCA 99
Query: 1810 YSLLVRADDGLQSSDM-----------RINITVSDVNDHTPKFSRPVYSFDIPEDTIPGS 1858
+ ++ ++ +I I V D ND+ P F PV + IPE+T+ S
Sbjct: 100 GASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINS 159
Query: 1859 LVAAILATDDDSGVNGEITY-IVNEDDEDGIFFLNPITG----VFNLTRLLDYEVQQYYI 1913
ATD D+G NG Y ++N G+ + G + + LD E + Y+
Sbjct: 160 RFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYV 219
Query: 1914 LTVRAEDGG--GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDA 1971
+ ++ EDGG + +T + + DVNDN P+F + EN PVG++V+ + TDA
Sbjct: 220 MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDA 279
Query: 1972 DDGINSQLTY----SIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIP 2027
D G N+++ Y +A + G++ V ++LDRE + + + V D P
Sbjct: 280 DIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP 339
Query: 2028 ASRFTSTAQVSIILLDVNDNPPT-----FLSP--KLTYIPENTPIDTVVFKAQATDPDSG 2080
A A V+I + DVNDNPP +SP Y+ E P++T + +D D+
Sbjct: 340 A-----RATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD 394
Query: 2081 PNS----YIE----YTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQP 2132
N +IE + L N++ + T + LD E ++ +VA+D G+P
Sbjct: 395 VNGKVICFIEREVPFHLKAVYDNQYLLET-------SSLLDYEGTKEFSFKIVASDSGKP 447
Query: 2133 SLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYG 2192
SL+ + V V + D NDN PIF Q + ++ ++EN G + + A D D G N + Y
Sbjct: 448 SLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
Query: 2193 IVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDI 2252
+ G F +D TG +T ++ DRE+ + TV A D G+ P + V + +LD
Sbjct: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
Query: 2253 NDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA 2312
ND P F + + V ENL T+ + D D G N ++ + N DN
Sbjct: 566 NDNSPKFTHNHFQFFVSENLPKY-STVGVITVTDADAGENKAVTLSILNDN-DNFVLDPY 623
Query: 2313 SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTF---ASKAY 2369
SG + S DRE + + + ATD G P + T + + V DVNDN P S
Sbjct: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
Query: 2370 FTTIPEDAPTGTDVLLVNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLDR 2425
F +P A G+ V V A D D NA ++ I+ GN++ F I+P TG I
Sbjct: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAP 743
Query: 2426 ETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
+ LVV SD G P+ L + V + V D N
Sbjct: 744 TDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 275 bits (702), Expect = 1e-72
Identities = 226/747 (30%), Positives = 345/747 (46%), Gaps = 61/747 (8%)
Query: 1638 LKEGEPIGT-----NVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTG-IIQ 1691
L E PIG N+ I AA+ G+ A + Y +VS + V + TG I
Sbjct: 34 LPENVPIGNIPKDLNISHINAAT--GTSASLVYRLVSKAGDAPLV----KVSSSTGEIFT 87
Query: 1692 TAAILDRE----------QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFP 1741
T+ +DRE + C + ++V + + +++I ++D NDN P+FP
Sbjct: 88 TSNRIDREKLCAGASYAEENECFFELEVVILPNDFF----RLIKIKIIVKDTNDNAPMFP 143
Query: 1742 TDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRID----PES---G 1794
+ ++++++ EN S+ +A D D G N + Y +++G F +D PE
Sbjct: 144 SPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG-QSVFGLDIVETPEGEKWP 202
Query: 1795 DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
LI + LDRE++ Y + ++ +DG +SS + +TVSDVND+ P F IP
Sbjct: 203 QLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDG---IFFLNPITGVFNLTRLLDYEV 1908
E+ G+ V + ATD D G N EI YI +F LN TG+ + R LD E
Sbjct: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREE 322
Query: 1909 QQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPP------IFSLNSYSTSLMENLPVGST 1962
+ +TV A DG V N+ DVNDNPP I S + + L E PV +
Sbjct: 323 TAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 1963 VLVFNVTDADDGINSQLTYSIASGDSLGQFTV-DKNGVLKVLKALDRESQSFYNLVVQVH 2021
+ + V+D D +N ++ I V D +L+ LD E ++ +
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 2022 DLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDSG 2080
D + TA V + L D NDNPP F P + + EN + ATD DSG
Sbjct: 443 DSGK---PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSG 499
Query: 2081 PNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEV 2140
N+ I Y L P + F + G + + DREE + TV A D G P L S V
Sbjct: 500 KNADIVYQ-LGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAV 558
Query: 2141 VVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQ 2200
+V VLD NDN+P F ++ ++EN + + + D D G N V I+N N N
Sbjct: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN- 617
Query: 2201 EFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFE 2260
F +D +G I DRE+ +Y V+ATD G PR+ T+ V+I ++D+ND PV
Sbjct: 618 -FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVI 676
Query: 2261 LSPYSVN---VPENLGTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGE 2315
P + + VP L +P +++ +V A D D G N++L Y + GN F + +G
Sbjct: 677 SPPSNTSFKLVP--LSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
Query: 2316 LGVTQSLDRETKERFVLMITATDSGSP 2342
+ + + L++ +D G P
Sbjct: 735 ITLEEKPAPTDVGLHRLVVNISDLGYP 761
Score = 251 bits (641), Expect = 1e-65
Identities = 202/673 (30%), Positives = 315/673 (46%), Gaps = 51/673 (7%)
Query: 2245 VSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV-ARDDDRGSNSKLSYVLFGGN 2303
+ I++ D ND P+F ++++PEN TL + + A D D G N Y L G
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPEN--TLINSRFPIPSATDPDTGFNGVQHYELLNGQ 185
Query: 2304 EDNAFTLSASGE------LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDV 2357
+ + E L V Q+LDRE K+ +V+ I D G+P + T + V V DV
Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 2358 NDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGG-------NSQFTI 2410
NDN P F IPE+AP GT V+ ++A+DAD NA IR I G F +
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 2411 NPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHP 2470
N +TG I LDRE + + V+ SD GS P + +V + VTDVNDNPP
Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASD-GSSTP--ARATVTINVTDVNDNPPNIDLRY 362
Query: 2471 YVT------HIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPL--RGAI 2522
++ ++ + + +TV+D D N ++ + FH+ + +
Sbjct: 363 IISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI--EREVPFHLKAVYDNQYL 420
Query: 2523 MAAGPL---NGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKV-RAKEQTFMFPE 2578
+ L G E +F + D G + V V+ ++ D P + E
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 2579 NQPVSSLVTTITGSSL-RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVV 2637
N +TTI+ + G+ G + F +D+ TG ++ S+ D E+ ++++
Sbjct: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
Query: 2638 WIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP---FISEILENLSPRKILTVSAMD 2694
+ ARD G PP S + +TVLD NDN+P F + F+SE L S ++TV+ D
Sbjct: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT--D 598
Query: 2695 KDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQS 2754
D+G N + I+N N ++F ++ +G I+S DRE+ S Y +K++D G P +S
Sbjct: 599 ADAGENKAVTLSILNDN--DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS 656
Query: 2755 TSVKVMINILDENDNAPRF----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYS 2810
++ KV IN++D NDN+P S VP ++ G V V D D G+NA +Y+
Sbjct: 657 STAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYT 716
Query: 2811 IMDASLP--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFV-TDIND 2867
I+ + F I+P TG+I + D +R+ V+ D G+ S + V +ND
Sbjct: 717 IVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVND 776
Query: 2868 NAPRFSRTSYYLD 2880
A SY D
Sbjct: 777 TA---GNASYIYD 786
Score = 248 bits (634), Expect = 8e-65
Identities = 230/765 (30%), Positives = 359/765 (46%), Gaps = 58/765 (7%)
Query: 1425 IFKSIVENIPIGT--SVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA 1482
I + + EN+PIG ++++ + + L Y ++ + + G I+T +
Sbjct: 30 IREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTS 89
Query: 1483 E-IDREFANLFELTVKAND-----QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALA 1536
IDRE + N+ + V + + L + I+V D NDN PMF S
Sbjct: 90 NRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINI 149
Query: 1537 ADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASALVPS 1593
+ P + +I S A DPD G NG YE++NG + IV+ G+ + +V
Sbjct: 150 SIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGE-KWPQLIVQQ 208
Query: 1594 QL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
L Y + + D G ++ ST L + + ++ PVF + + + E P+G
Sbjct: 209 NLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVG 268
Query: 1646 TNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACL 1704
T+VI + A + GS A + YI + T RLF + TG+I LDRE+ A +
Sbjct: 269 TSVIQLHATDADIGSNAEIR-YIFGAQVAPAT-KRLFALNNTTGLITVQRSLDREETA-I 325
Query: 1705 YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGDGSK 1758
+ V V A + S+ RA V I + D+NDNPP + + + E +K
Sbjct: 326 HKVTVLASDGSST---PARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 1759 IMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRR-LDRERRSKYSL-LVRA 1816
I +T D D N V I + ++ L+ T LD E ++S +V +
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 1817 DDGLQSSDMR--INITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNG 1874
D G S + + + + D ND+ P F++PV + E+ G + I ATD+DSG N
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 1875 EITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQ--FTTIRVYF 1932
+I Y + + F L+ TGV +R+ D E Q+ +I TV A D G + V
Sbjct: 503 DIVYQLGPN--ASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIV 560
Query: 1933 NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQF 1992
+LD NDN P F+ N + + ENLP STV V VTDAD G N +T SI + + F
Sbjct: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND--NF 618
Query: 1993 TVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+D +GV+K + DRE QS Y V+ D Q P S STA+V+I ++DVNDN P
Sbjct: 619 VLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS---STAKVTINVMDVNDNSPVV 675
Query: 2052 LSP----KLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDG 2104
+SP +P + +VV + A D D+G N+ ++YT+++ GN F I + G
Sbjct: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVS--GNNKGLFRIDPVTG 733
Query: 2105 EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDIND 2149
+ L + +V + L V +D G P S +V++ L +ND
Sbjct: 734 NITLEEKPAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVND 776
Score = 248 bits (633), Expect = 1e-64
Identities = 223/773 (28%), Positives = 357/773 (46%), Gaps = 63/773 (8%)
Query: 259 VPEDAVVGS--SVLQVAAADADEGTNADIRYRLQDEGTP---FQMDPETG-LITVREPLD 312
+PE+ +G+ L ++ +A GT+A + YRL + ++ TG + T +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 313 FE---ARRQYSLTVQAM-DRGVPSLTGRAEALIQLL----DVNDNDPVVKFRYFPATSRY 364
E A Y+ + + V L LI++ D NDN P+ FP+
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPM-----FPSPVIN 148
Query: 365 ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV----QSSKVPNLSLI 420
S+ EN + + + + TD D+ NG ++L G ++ + K P L
Sbjct: 149 ISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLI-- 205
Query: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
V LDRE+ +Y + + V D G P +SS A L + V+D+ND+ PVF +
Sbjct: 206 -VQQNLDREQKDTYVMKIKVEDG-GTPQ------KSSTAILQVTVSDVNDNRPVFKEGQV 257
Query: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI---VSGNGLGWFHISEHSGLVTTGSS 537
V++ E AP G+ V + ATD D G NA +RY V+ F ++ +GL+T S
Sbjct: 258 EVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRS 317
Query: 538 GGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFS-----QPEGYDVSV 592
LDRE + + + A D P + A + + + DVND P P V +
Sbjct: 318 --LDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNIDLRYIISPINGTVYL 373
Query: 593 VENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGR---LSTISSLDR 649
E P T++ ++ +D D NG V ++ F L V L T S LD
Sbjct: 374 SEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP----FHLKAVYDNQYLLETSSLLDY 429
Query: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYIT 709
E +S ++A+D G P + A + V L D NDN P+F + EN G Y+T
Sbjct: 430 EGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLT 489
Query: 710 TVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
T+SATD D G N + Y + + S F ++ ++GV++ DREE+ + + A D G
Sbjct: 490 TISATDEDSGKNADIVYQLGP-NASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNG 548
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYL 829
+QA V +TVLD DN P F+ + F V EN+ VG ++ + D N +
Sbjct: 549 TPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVT 608
Query: 830 ITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG---TVTGDTMVNITVKDL 886
++ + F ++ +G + + DRE+QS Y V A+ G + V I V D+
Sbjct: 609 LSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDV 668
Query: 887 NDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDEGVNGMVLYSL-KQNPKNLFAI 942
NDNSP + + + V + G + + AVD D G+N + Y++ N K LF I
Sbjct: 669 NDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRI 728
Query: 943 NEKNGTISL-LGPLDVHAGSYQIEILASDMGVPQ-LSSSVILTVYVHDVNDNS 993
+ G I+L P G +++ + SD+G P+ L + V++ +YV+D N+
Sbjct: 729 DPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNA 781
Score = 238 bits (607), Expect = 1e-61
Identities = 178/580 (30%), Positives = 285/580 (49%), Gaps = 34/580 (5%)
Query: 1696 LDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGD 1755
LDREQ Y++ + +E ++ A +++T+ D+NDN PVF +++ + EN
Sbjct: 210 LDREQKDT-YVMKI-KVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
Query: 1756 GSKIMQLTAMDADEGANALVTY----TIISGADDSFRIDPESGDLIATRRLDRERRSKYS 1811
G+ ++QL A DAD G+NA + Y + F ++ +G + R LDRE + +
Sbjct: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
Query: 1812 LLVRADDGLQS-SDMRINITVSDVNDHTPKFS-----RPVY-SFDIPEDTIPGSLVAAIL 1864
+ V A DG + + + I V+DVND+ P P+ + + E + +A I
Sbjct: 328 VTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
Query: 1865 ATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-- 1922
+D D+ VNG++ + + + + + + LLDYE + + + A D G
Sbjct: 388 VSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKP 447
Query: 1923 --GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT 1980
Q +RV + D NDNPPIF+ S+ EN G + + TD D G N+ +
Sbjct: 448 SLNQTALVRV--KLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIV 505
Query: 1981 YSIASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSI 2039
Y + G + F +D K GVL + DRE Q + V D P S A V +
Sbjct: 506 YQL--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPP---LQSQAAVIV 560
Query: 2040 ILLDVNDNPPTFLSPKLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFS 2098
+LD NDN P F ++ EN P + V TD D+G N + ++LN N F
Sbjct: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN-FV 619
Query: 2099 IGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIF---- 2154
+ G ++ DRE+ S+YT V ATD GQP SS+ +V + V+D+NDN+P+
Sbjct: 620 LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP 679
Query: 2155 AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVA 2214
+ +K+ + + + G+ + +VFA D D G N +++Y IV+GN FRID VTG IT+
Sbjct: 680 SNTSFKL-VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
Query: 2215 KPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDIND 2254
+ + L V +D G P++ T+ +V L +ND
Sbjct: 739 EKPAPTDVGLHRLVVNISDLG-YPKS-LHTLVLVFLYVND 776
Score = 206 bits (524), Expect = 5e-52
Identities = 178/695 (25%), Positives = 317/695 (45%), Gaps = 51/695 (7%)
Query: 2880 DCPELTEIGS--KVTQVFATDPDEGSNGQVFYFIKSQS---EYFRINATTGEIF--NKQI 2932
+ PE IG+ K + + G++ + Y + S++ +++++TGEIF + +I
Sbjct: 33 ELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRI 92
Query: 2933 LKYQNVTGFSNVNINRHSF----IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKY 2988
+ + G S N F ++ +D + I + D+NDNAP F
Sbjct: 93 DREKLCAGASYAEENECFFELEVVILPND-----FFRLIKIKIIVKDTNDNAPMFPSPVI 147
Query: 2989 FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLD-----NDTGW--I 3041
+ +N + ++ + + D D G N Y + N + F LD W +
Sbjct: 148 NISIPENTLINSRF-PIPSATDPDTGFNGVQHYELLNGQSV--FGLDIVETPEGEKWPQL 204
Query: 3042 SVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPES 3101
V +L + + + + +D G P SS A + +TV++ N + P F + + IPE+
Sbjct: 205 IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPEN 264
Query: 3102 HSIGSIVRTVSARDRDAAMNGLIKYSISSG---NEEGIFAINSSTGILTLAKALDYELCQ 3158
+G+ V + A D D N I+Y + + +FA+N++TG++T+ ++LD E
Sbjct: 265 APVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETA 324
Query: 3159 KHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL--ENAPSGTT 3212
H++T+ A DG + +VT+NV DVNDN P ++ TV E P T
Sbjct: 325 IHKVTVLASDGS--STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 3213 VIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAF 3271
+ + +D D+ N VI + + L + N ++ T LD+E + + + A
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 3272 NVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDG 3331
+ A V ++L+ N+ P F + +SE +G + + A+D D G +
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 3332 EVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTV 3391
++ Y + N+ F +++KTG + S + DRE++ER V A++ G+ + V
Sbjct: 503 DIVYQLGPNA--SFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQS--QAAV 558
Query: 3392 NVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNEN 3450
VTVLD ND P FT N + +SE +P + V ++ D+D+ + + N+N
Sbjct: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADA---GENKAVTLSILNDN 615
Query: 3451 GAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPML 3510
F ++P +G I DRE Y V A D G P + +A + + + D+NDN P++
Sbjct: 616 DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVV 675
Query: 3511 -----TVSEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
S V + PG++V + + D D N
Sbjct: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMN 710
Score = 197 bits (502), Expect = 2e-49
Identities = 196/673 (29%), Positives = 301/673 (44%), Gaps = 54/673 (8%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEE 3134
+ I V + N + P F ++ +IPE+ I S SA D D NG+ Y + +G
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSV 187
Query: 3135 -GIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ + + G L + + LD E + M I DGG ++ + V V DVND
Sbjct: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND 247
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYT----VQSSDSDLFVIDP 3245
N PVF + ENAP GT+VI L+ATDAD G+NA I Y V + LF ++
Sbjct: 248 NRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNN 307
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTN------EYVPRFV 3299
TG+IT Q LD E + +TV A + + T+N+ N Y+ +
Sbjct: 308 TTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPI 367
Query: 3300 SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
+ Y +SE P T + + SD+D +G+V I R+ F + Y+
Sbjct: 368 NGTVY--LSEKDPVNTKIALITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLE 422
Query: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
S +LD E + S K++A + G + + V V + D ND PPIF + + +SE
Sbjct: 423 TSSLLDYEGTKEFSFKIVASDSG--KPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
G ++T +SA D DS + + Y +G F ++ +TG +T + DRE
Sbjct: 481 NNRRGLYLTTISATDEDSGKN-ADIVYQLGPNAS--FFDLDRKTGVLTASRVFDREEQER 537
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
+ +V A D+GTP A+++VT+ D NDN P T + + V EN + V + T
Sbjct: 538 FIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT 597
Query: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
D D N+ LS F L +GV+ + DREQ + + V D G P
Sbjct: 598 DADAGENKA----VTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
Query: 3593 QMSSTGTVHITVIDQNDN------PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV--- 3643
SST V I V+D NDN P + + ++ + PG ++ V D D
Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPL---SAIPGSVVAEVFAVDVDTGMN 710
Query: 3644 LDSFHCSLTSGVTSLFSIP--GGTCDLNSQPRSTD-GTFDLTV-LSNDGVHSTVTSNIRV 3699
+ + ++ LF I G L +P TD G L V +S+ G ++ + + V
Sbjct: 711 AELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLV 770
Query: 3700 FFAGFSNATVDNS 3712
F + N T N+
Sbjct: 771 FL--YVNDTAGNA 781
Score = 174 bits (442), Expect = 2e-42
Identities = 160/546 (29%), Positives = 254/546 (46%), Gaps = 44/546 (8%)
Query: 3098 IPESHSIGSIVRTVSARDRDAAMN---GLIKYSISSGNEEGIFAINSSTG-ILTLAKALD 3153
+PE+ IG+I + ++ +AA L+ +S + + ++SSTG I T + +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 3154 YE-LCQK----------HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 3202
E LC E+ + + + + + V D NDN+P+F S +
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFR---LIKIKIIVKDTNDNAPMFPSPVINIS 150
Query: 3203 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGV----ITTQGFL 3256
+ EN + +ATD D+G N V Y + + S L +++ G + Q L
Sbjct: 151 IPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNL 210
Query: 3257 DFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTI 3316
D E K +Y + +K + ++ S A + + + N+ P F I E AP GT
Sbjct: 211 DREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTS 270
Query: 3317 VGEVFASDRDLGTDGEVHYLIFGN----SRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
V ++ A+D D+G++ E+ Y IFG + K+ F +N TG I V LDRE+ +
Sbjct: 271 VIQLHATDADIGSNAEIRY-IFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVT 329
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYS-----VQISEGVPIGTHVTFVS 3427
VLA + S VT+NVT ++ N P I I S V +SE P+ T + ++
Sbjct: 330 VLASDGSSTPARAT--VTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
Query: 3428 AFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGT 3487
D D+ + + FI ++ + ++ LD E ++ ++A DSG
Sbjct: 388 VSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGK 446
Query: 3488 PSATGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFT 3545
PS +A + V LED NDN P+ V E V EN R G + T+ +TD D N
Sbjct: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKN-ADIV 505
Query: 3546 YYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITV 3604
Y L GP S+F L GVL+ +R DRE+ F +V +D+G P + S V +TV
Sbjct: 506 YQL---GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTV 562
Query: 3605 IDQNDN 3610
+D+NDN
Sbjct: 563 LDENDN 568
Score = 129 bits (324), Expect = 7e-29
Identities = 129/475 (27%), Positives = 206/475 (43%), Gaps = 57/475 (12%)
Query: 3206 NAPSGTTVIHLNATDADSGTNAVIAYTVQSS--DSDLFVIDPNTG-VITTQGFLDFETKQ 3262
N P + H+NA +GT+A + Y + S D+ L + +TG + TT +D E
Sbjct: 42 NIPKDLNISHINAA---TGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREK-- 96
Query: 3263 SYHLTVKAFNVPDEERCSFAT--------------VNIQLKGTNEYVPRFVSKLYYFEIS 3308
+ +E C F + I +K TN+ P F S + I+
Sbjct: 97 ----LCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPV----IN 148
Query: 3309 EAAPKGTIVGEVF----ASDRDLGTDGEVHYLIFGNSRKKGFQI-----NKKTGQIYVSG 3359
+ P+ T++ F A+D D G +G HY + G I +K Q+ V
Sbjct: 149 ISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQ 208
Query: 3360 ILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVP 3418
LDRE+++ +K+ ++ G+ + + + VTV D ND P+F V I E P
Sbjct: 209 NLDREQKDTYVMKIKVEDGGTPQKSST--AILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
Query: 3419 IGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FSINPQTGQITVTAELDRETLPI 3475
+GT V + A D+D I S + Y G+ F++N TG ITV LDRE I
Sbjct: 267 VGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAI 325
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGP------MLTVSEGEV-MENKRP-GTLV 3527
+ ++VLA D + A + ++ VT D+NDN P +++ G V + K P T +
Sbjct: 326 HKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKI 383
Query: 3528 MTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTK 3587
+ +D D N G ++ P +L T+ +D E +F +V
Sbjct: 384 ALITVSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 3588 DSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPD 3642
DSG P ++ T V + + D+NDNP I ++ N G L ++ D D
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDED 497
Score = 57.8 bits (138), Expect = 3e-07
Identities = 81/333 (24%), Positives = 134/333 (40%), Gaps = 54/333 (16%)
Query: 3408 IYSV--QISEGVPIGT-----HVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTG 3460
IY++ ++ E VPIG +++ ++A S R + + ++ TG
Sbjct: 27 IYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL---VSKAGDAPLVKVSSSTG 83
Query: 3461 QITVTAE-LDRETLP-----------IYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP 3508
+I T+ +DRE L + L V+ + + + + ++D NDN P
Sbjct: 84 EIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAP 140
Query: 3509 MLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGV- 3565
M V + EN + +TDPD N G Y LL+ S F L
Sbjct: 141 MFPSPVINISIPENTLINSRFPIPSATDPDTGFN-GVQHYELLN---GQSVFGLDIVETP 196
Query: 3566 -------LSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVE 3618
L + +DREQ + + + +D G PQ SST + +TV D NDN + +
Sbjct: 197 EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQ 256
Query: 3619 IFVNYYGNLFPGGILGSVKPQDPDVLDS------FHCSLTSGVTSLFSIPGGTCDLNSQP 3672
+ V+ N G + + D D+ + F + LF++ T L +
Sbjct: 257 VEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL-NNTTGLITVQ 315
Query: 3673 RSTD----GTFDLTVLSNDG----VHSTVTSNI 3697
RS D +TVL++DG +TVT N+
Sbjct: 316 RSLDREETAIHKVTVLASDGSSTPARATVTINV 348
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 354 bits (908), Expect = 1e-96
Identities = 263/805 (32%), Positives = 414/805 (51%), Gaps = 67/805 (8%)
Query: 25 LRVFWLLSLLPGQAWVHGAEPRQ-VFQVLEEQPPGTLVGTIQ-------------TRPGF 70
LR F+LL+ L + A ++ ++ + EE P +G I T
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
Query: 71 TYRLSESHA---LFAINSSTGALYTTST-IDRESLPSDV-----------INLVVLSSAP 115
YRL L ++SSTG ++TTS IDRE L + + +V+L +
Sbjct: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDF 122
Query: 116 TYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYR 175
+++++V+D NDNAP+FP P I ++ E++ + + +ATD D G NGV H Y
Sbjct: 123 FRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQH--YE 180
Query: 176 IIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQ 235
++ G F LDI P GE + L+ + LDRE Y + ++VED G P++
Sbjct: 181 LLNGQSV--FGLDIVETPEGE-KWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAI 237
Query: 236 VNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP 295
+ VTV D+NDN PVF + +PE+A VG+SV+Q+ A DAD G+NA+IRY + P
Sbjct: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
Query: 296 -----FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDND 350
F ++ TGLITV+ LD E + +TV A D S RA I + DVNDN
Sbjct: 298 ATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGS--STPARATVTINVTDVNDNP 355
Query: 351 PVVKFRY-FPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
P + RY + + E V T +AL+TV+D D+ NG + I + F +
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD-VNGKVICFI---EREVPFHL 411
Query: 410 QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIN 469
+ + N L++ +S LD E ++ + SD+ G P + + A + + + D N
Sbjct: 412 K-AVYDNQYLLETSSLLDYEGTKEFSFKIVASDS-GKP------SLNQTALVRVKLEDEN 463
Query: 470 DHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHS 529
D+PP+F+Q V +++SE G Y++ ISATD DSG NA++ Y + G +F + +
Sbjct: 464 DNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKT 521
Query: 530 GLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYD 589
G++T +S DRE + + ++ARD G P S A ++VT+LD ND P F+ +
Sbjct: 522 GVLT--ASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH-NHFQ 578
Query: 590 VSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDR 649
V EN P + + ++ TD D G+N V S+ D +F LDP SG + + S DR
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSIL---NDNDNFVLDPYSGVIKSNVSFDR 635
Query: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPV---QYFAHIKENEPGGS 706
E+Q+ Y+ V ATD G PP+SS A++ ++++D+NDNSPV F + + GS
Sbjct: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
Query: 707 YITTVSATDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVA 765
+ V A D D G N +KY+I +G ++ F+++ +G I+ + ++L +
Sbjct: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
Query: 766 TDGGNLQSPNQ-AIVTITVLDTQDN 789
+D G +S + +V + V DT N
Sbjct: 756 SDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 306 bits (783), Expect = 4e-82
Identities = 236/739 (31%), Positives = 352/739 (47%), Gaps = 51/739 (6%)
Query: 804 ENVALG-----YHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQL-TTANVIDRE 857
ENV +G ++ ++A+T S + L++ + ++ TG++ TT+N IDRE
Sbjct: 36 ENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDRE 95
Query: 858 E-----------QSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENW 906
+ + F++L+VV + I VKD NDN+P F + ++++ EN
Sbjct: 96 KLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT 155
Query: 907 QAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAIN-------EKNGTISLLGPLD-VH 958
A DPD G NG+ Y L N +++F ++ EK + + LD
Sbjct: 156 LINSRFPIPSATDPDTGFNGVQHYELL-NGQSVFGLDIVETPEGEKWPQLIVQQNLDREQ 214
Query: 959 AGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKV 1018
+Y ++I D G PQ SS+ IL V V DVNDN PVF + EV + E+ PV + ++
Sbjct: 215 KDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQL 274
Query: 1019 QASDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASD 1074
A+D D G+N EI Y +F G + ++ LDRE + + V+ASD
Sbjct: 275 HATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
Query: 1075 RAVEPLSATVNVTVILEDVNDNRP------LFNSTNYTFYFEEEQRAGSFVGKVSAVDKD 1128
+ P ATV + V DVNDN P + + N T Y E+ + + ++ DKD
Sbjct: 335 GSSTPARATVTINV--TDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD 392
Query: 1129 FGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQ 1188
NG+V E P F L A+ N + + SL+ GT FSF ++A+D G P
Sbjct: 393 TDVNGKVICFIEREVP-FHLKAV---YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPS 448
Query: 1189 PLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYS 1248
L A V V ++D NDN P F + + ++SE+ + +SA+D D G N I Y
Sbjct: 449 -LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
Query: 1249 IIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDE 1308
+ G F +D +G +T D E + + A D+GT PL S + + +LDE
Sbjct: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
Query: 1309 NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN 1368
NDN+P F + V EN+ V +T TD+D+G+N + SI N++ F + P
Sbjct: 566 NDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSI--LNDNDNFVLDPY 623
Query: 1369 TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPP---SFPPGDI 1425
+G I D E QS Y ++ A D G+PPRSST V I+V D NDN P S P
Sbjct: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
Query: 1426 FKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEID 1485
FK + + G+ V V A D D +N +L YTI+ +G F ID V G I +
Sbjct: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKG-LFRIDPVTGNITLEEKPA 742
Query: 1486 REFANLFELTVKANDQAVP 1504
L L V +D P
Sbjct: 743 PTDVGLHRLVVNISDLGYP 761
Score = 299 bits (765), Expect = 5e-80
Identities = 214/671 (31%), Positives = 334/671 (49%), Gaps = 58/671 (8%)
Query: 982 LTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTG 1041
+ + V D NDN+P+F +++ E+ +NSRF A+D D+G NG Y + G +
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS- 186
Query: 1042 DAFGI----FPDG----QLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDV 1093
FG+ P+G QL ++ LDRE +D YV+ + D S+T + V + DV
Sbjct: 187 -VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 1094 NDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF-EMVQPD----FEL 1148
NDNRP+F + E G+ V ++ A D D G N E+RY F V P F L
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 1149 HAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAP 1208
+ +G IT DRE TA+ TV+A+D G P + ATV + + D+NDN P
Sbjct: 306 NNTTGLITVQRSLDREE------TAIHKVTVLASD-GSSTPAR--ATVTINVTDVNDNPP 356
Query: 1209 ----KFLKDFYQATI--SESAANLTQVLRVSASDVDEGNNGLIHYSI-------IKGNEE 1255
+++ T+ SE T++ ++ SD D NG + I +K +
Sbjct: 357 NIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD 416
Query: 1256 RQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF 1315
Q+ ++++S LDYE T +S I A DSG LN T + + + DENDN P F
Sbjct: 417 NQYLLETSS-------LLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIF 469
Query: 1316 PKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLA 1375
+ + + V EN R G +++++ATD DSG NAD+ Y + N F + TG + +
Sbjct: 470 NQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKTGVLTAS 527
Query: 1376 KKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI 1435
+ D E Q + +TA+D G PP S +V++ V D NDN P F + EN+P
Sbjct: 528 RVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK 587
Query: 1436 GTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELT 1495
++V +T D DA N ++ +I+ ++F +D G I +N DRE + +
Sbjct: 588 YSTVGVITVTDADAGENKAVTLSILND---NDNFVLDPYSGVIKSNVSFDREQQSSYTFD 644
Query: 1496 VKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAA----DPSAVIGSVLTTIM 1551
VKA D P R + VTI V D+NDN P+ IS + + SA+ GSV+ +
Sbjct: 645 VKATDGGQP---PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVF 701
Query: 1552 AADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASALVPSQL-IYNLIVSATDLGPE 1609
A D D G N E++Y I++G+ F +D +G++ + P+ + ++ L+V+ +DLG
Sbjct: 702 AVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
Query: 1610 RRKSTTELTII 1620
+ T L +
Sbjct: 762 KSLHTLVLVFL 772
Score = 295 bits (755), Expect = 8e-79
Identities = 223/718 (31%), Positives = 352/718 (49%), Gaps = 55/718 (7%)
Query: 2577 PENQPVSSL-----VTTITGSSLRGEPMSYYIASGNLGNT--FQIDQLTGQV-SISQPLD 2628
PEN P+ ++ ++ I ++ + Y + S G+ ++ TG++ + S +D
Sbjct: 35 PENVPIGNIPKDLNISHINAATGTSASLVYRLVS-KAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 2629 FEKIQKYVVWIEARDGGFP--------PFSSYEKLDITVLDVNDNAPIFKEDPFISEILE 2680
EK+ + E + F F K+ I V D NDNAP+F I E
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPE 153
Query: 2681 N-LSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSI-----NHATGEIRSVRPLDRE 2734
N L + SA D D+G NG YE++NG I ++ + LDRE
Sbjct: 154 NTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDRE 213
Query: 2735 KVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTR 2793
+ YV+ IK D G+P +S++ + + + D NDN P F + H+PEN+P+G +V +
Sbjct: 214 QKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQ 273
Query: 2794 VTTSDEDIGINAISRYSIMDASLP-----FTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+ +D DIG NA RY P F +N +TG I + R L+RE+T +++ V A
Sbjct: 274 LHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLAS 333
Query: 2849 DSGWTVS-TDVTIFVTDINDNAPRFSRTSYYLDCP--------ELTEIGSKVTQVFATDP 2899
D T + VTI VTD+NDN P Y+ P E + +K+ + +D
Sbjct: 334 DGSSTPARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDK 391
Query: 2900 DEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRG 2959
D NG+V FI+ + F + A N+ +L+ ++ + SF + +SD G
Sbjct: 392 DTDVNGKVICFIEREVP-FHLKAVYD---NQYLLETSSLLDYEGTK--EFSFKIVASDSG 445
Query: 2960 KPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEV 3019
KPSL V + + D NDN P F + V++N + G L ++A D+ D G N+++
Sbjct: 446 KPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDE-DSGKNADI 504
Query: 3020 EYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITV 3079
Y + + F LD TG ++ + + + F TVTA+D G PPL SQA V +TV
Sbjct: 505 VYQLGPNASF--FDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTV 562
Query: 3080 TEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAI 3139
+EN ++P+F+ +H + E+ S V ++ D DA N + SI + N+ F +
Sbjct: 563 LDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN--FVL 620
Query: 3140 NSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFL---S 3196
+ +G++ + D E + + A DGG R+ VT+NV+DVNDNSPV + S
Sbjct: 621 DPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS 680
Query: 3197 DDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQ 3253
+ F V +A G+ V + A D D+G NA + YT+ S ++ LF IDP TG IT +
Sbjct: 681 NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
Score = 294 bits (753), Expect = 1e-78
Identities = 239/766 (31%), Positives = 362/766 (47%), Gaps = 66/766 (8%)
Query: 698 IKENEPGGSYIT--TVSATDPDLGTNGTVKYSI--SAGDRSRFQVNAQSG-VISTRMALD 752
+ EN P G+ +S + GT+ ++ Y + AGD +V++ +G + +T +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 753 REEKTA-----------YQLQIVATDGGNLQSPNQAI----VTITVLDTQDNPPVFSQVA 797
RE+ A ++L++V PN + I V DT DN P+F
Sbjct: 94 REKLCAGASYAEENECFFELEVVIL-------PNDFFRLIKIKIIVKDTNDNAPMFPSPV 146
Query: 798 YSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQK-GMFAINQVTG----QLTT 850
+ + EN + SA+ D N Y + G G+ + G QL
Sbjct: 147 INISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIV 206
Query: 851 ANVIDREEQSFYQLKV-VASGGT--VTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQ 907
+DRE++ Y +K+ V GGT + ++ +TV D+NDN P F + V++ EN
Sbjct: 207 QQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
Query: 908 AGHSIFQAKAVDPDEGVNGMVLY----SLKQNPKNLFAINEKNGTISLLGPLD-VHAGSY 962
G S+ Q A D D G N + Y + K LFA+N G I++ LD +
Sbjct: 267 VGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIH 326
Query: 963 QIEILASDMGVPQLSSSVILTVYVHDVNDNSP------VFDQLSYEVTLSESEPVNSRFF 1016
++ +LASD ++V T+ V DVNDN P + ++ V LSE +PVN++
Sbjct: 327 KVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIA 384
Query: 1017 KVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ--LYIKSELDRELQDRYVLMVVASD 1074
+ SDKD+ NG++ I ++ D Q L S LD E + +VASD
Sbjct: 385 LITVSDKDTDVNGKVICFIEREVPFHLKAVY-DNQYLLETSSLLDYEGTKEFSFKIVASD 443
Query: 1075 RAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGE 1134
L+ T V V LED NDN P+FN E R G ++ +SA D+D G N +
Sbjct: 444 SGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD 503
Query: 1135 VRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQA 1194
+ Y F+L +G +T + FDRE R F FTV A D G P PL+ QA
Sbjct: 504 IVYQLGPNASFFDLDRKTGVLTASRVFDREEQER------FIFTVTARDNGTP-PLQSQA 556
Query: 1195 TVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE 1254
V V + D NDN+PKF + +Q +SE+ + V ++ +D D G N + SI+ N+
Sbjct: 557 AVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND 616
Query: 1255 ERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTP- 1313
F +D SG + D E +Y+ ++A D G P +ST + I+++D NDN+P
Sbjct: 617 --NFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPV 674
Query: 1314 --SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGS 1371
S P +T F V + G +V+ V A D D+G NA+L Y+I NN G F I P TG+
Sbjct: 675 VISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
Query: 1372 IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVV-IHVRDFNDN 1416
I L +K L++L + D G P T+ +V ++V D N
Sbjct: 735 ITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 286 bits (732), Expect = 4e-76
Identities = 232/760 (30%), Positives = 363/760 (47%), Gaps = 61/760 (8%)
Query: 1953 LMENLPVGSTVLVFNVT--DADDGINSQLTYSIAS--GDS-LGQFTVDKNGVLKVLKALD 2007
L EN+P+G+ N++ +A G ++ L Y + S GD+ L + + + +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 2008 RE-----------SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL 2056
RE ++ F+ L V + LP + F ++ II+ D NDN P F SP +
Sbjct: 94 REKLCAGASYAEENECFFELEVVI--LP----NDFFRLIKIKIIVKDTNDNAPMFPSPVI 147
Query: 2057 TY-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKFSIGTIDGE----VRLT 2109
IPENT I++ ATDPD+G N Y LLN + + T +GE + +
Sbjct: 148 NISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQ 207
Query: 2110 GELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLT 2169
LDRE+ Y + + D G P SS+ + V V D+NDN P+F + +V I EN
Sbjct: 208 QNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
Query: 2170 GTDIIQVFAADGDEGTNGQVRY---GIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYH 2226
GT +IQ+ A D D G+N ++RY V T + F +++ TG ITV + LDRE+T +
Sbjct: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
Query: 2227 LTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL----SPYSVNV-PENLGTLPRTILQ 2281
+TV A+D STP T T+++ D+ND P +L SP + V + I
Sbjct: 328 VTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIAL 385
Query: 2282 VVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE----LGVTQSLDRETKERFVLMITAT 2337
+ D D N K+ + + F L A + L + LD E + F I A+
Sbjct: 386 ITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 2338 DSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA 2397
DSG P+L T + V ++D NDN P F ++ E+ G + ++A+D D+ KNA
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 2398 -VIRIIGGN-SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
++ +G N S F ++ TG + S + DRE ++ + V D G+P PL S +V+VT
Sbjct: 503 DIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTP-PLQSQAAVIVT 561
Query: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHI 2515
V D NDN P+F H+ + + S V +TVTDAD G N + S+ N + F +
Sbjct: 562 VLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDN-DNFVL 620
Query: 2516 DPLRGAIMA--AGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQT 2573
DP G I + + S TF V DGG P++ + VT+ ++ D V +
Sbjct: 621 DPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS 680
Query: 2574 FMFPENQPVSSL-------VTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQP 2626
+ P+S++ V + + + Y I SGN F+ID +TG +++ +
Sbjct: 681 NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEK 740
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNA 2666
+ + + + D G+P S L + L VND A
Sbjct: 741 PAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVNDTA 778
Score = 281 bits (718), Expect = 1e-74
Identities = 221/757 (29%), Positives = 351/757 (46%), Gaps = 63/757 (8%)
Query: 1753 IGDGSKIMQLTAMDADEGANALVTYTIISGADDS--FRIDPESGDLIAT-RRLDRERRSK 1809
IG+ K + ++ ++A G +A + Y ++S A D+ ++ +G++ T R+DRE+
Sbjct: 40 IGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCA 99
Query: 1810 YSLLVRADDGLQSSDM-----------RINITVSDVNDHTPKFSRPVYSFDIPEDTIPGS 1858
+ ++ ++ +I I V D ND+ P F PV + IPE+T+ S
Sbjct: 100 GASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINS 159
Query: 1859 LVAAILATDDDSGVNGEITY-IVNEDDEDGIFFLNPITG----VFNLTRLLDYEVQQYYI 1913
ATD D+G NG Y ++N G+ + G + + LD E + Y+
Sbjct: 160 RFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYV 219
Query: 1914 LTVRAEDGG--GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDA 1971
+ ++ EDGG + +T + + DVNDN P+F + EN PVG++V+ + TDA
Sbjct: 220 MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDA 279
Query: 1972 DDGINSQLTY----SIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIP 2027
D G N+++ Y +A + G++ V ++LDRE + + + V D P
Sbjct: 280 DIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP 339
Query: 2028 ASRFTSTAQVSIILLDVNDNPPT-----FLSP--KLTYIPENTPIDTVVFKAQATDPDSG 2080
A A V+I + DVNDNPP +SP Y+ E P++T + +D D+
Sbjct: 340 A-----RATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD 394
Query: 2081 PNS----YIE----YTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQP 2132
N +IE + L N++ + T + LD E ++ +VA+D G+P
Sbjct: 395 VNGKVICFIEREVPFHLKAVYDNQYLLET-------SSLLDYEGTKEFSFKIVASDSGKP 447
Query: 2133 SLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYG 2192
SL+ + V V + D NDN PIF Q + ++ ++EN G + + A D D G N + Y
Sbjct: 448 SLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
Query: 2193 IVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDI 2252
+ G F +D TG +T ++ DRE+ + TV A D G+ P + V + +LD
Sbjct: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
Query: 2253 NDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA 2312
ND P F + + V ENL T+ + D D G N ++ + N DN
Sbjct: 566 NDNSPKFTHNHFQFFVSENLPKY-STVGVITVTDADAGENKAVTLSILNDN-DNFVLDPY 623
Query: 2313 SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTF---ASKAY 2369
SG + S DRE + + + ATD G P + T + + V DVNDN P S
Sbjct: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
Query: 2370 FTTIPEDAPTGTDVLLVNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLDR 2425
F +P A G+ V V A D D NA ++ I+ GN++ F I+P TG I
Sbjct: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAP 743
Query: 2426 ETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
+ LVV SD G P+ L + V + V D N
Sbjct: 744 TDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Score = 275 bits (702), Expect = 1e-72
Identities = 226/747 (30%), Positives = 345/747 (46%), Gaps = 61/747 (8%)
Query: 1638 LKEGEPIGT-----NVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTG-IIQ 1691
L E PIG N+ I AA+ G+ A + Y +VS + V + TG I
Sbjct: 34 LPENVPIGNIPKDLNISHINAAT--GTSASLVYRLVSKAGDAPLV----KVSSSTGEIFT 87
Query: 1692 TAAILDRE----------QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFP 1741
T+ +DRE + C + ++V + + +++I ++D NDN P+FP
Sbjct: 88 TSNRIDREKLCAGASYAEENECFFELEVVILPNDFF----RLIKIKIIVKDTNDNAPMFP 143
Query: 1742 TDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRID----PES---G 1794
+ ++++++ EN S+ +A D D G N + Y +++G F +D PE
Sbjct: 144 SPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG-QSVFGLDIVETPEGEKWP 202
Query: 1795 DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
LI + LDRE++ Y + ++ +DG +SS + +TVSDVND+ P F IP
Sbjct: 203 QLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDG---IFFLNPITGVFNLTRLLDYEV 1908
E+ G+ V + ATD D G N EI YI +F LN TG+ + R LD E
Sbjct: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREE 322
Query: 1909 QQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPP------IFSLNSYSTSLMENLPVGST 1962
+ +TV A DG V N+ DVNDNPP I S + + L E PV +
Sbjct: 323 TAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 1963 VLVFNVTDADDGINSQLTYSIASGDSLGQFTV-DKNGVLKVLKALDRESQSFYNLVVQVH 2021
+ + V+D D +N ++ I V D +L+ LD E ++ +
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 2022 DLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDSG 2080
D + TA V + L D NDNPP F P + + EN + ATD DSG
Sbjct: 443 DSGK---PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSG 499
Query: 2081 PNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEV 2140
N+ I Y L P + F + G + + DREE + TV A D G P L S V
Sbjct: 500 KNADIVYQ-LGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAV 558
Query: 2141 VVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQ 2200
+V VLD NDN+P F ++ ++EN + + + D D G N V I+N N N
Sbjct: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN- 617
Query: 2201 EFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFE 2260
F +D +G I DRE+ +Y V+ATD G PR+ T+ V+I ++D+ND PV
Sbjct: 618 -FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVI 676
Query: 2261 LSPYSVN---VPENLGTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGE 2315
P + + VP L +P +++ +V A D D G N++L Y + GN F + +G
Sbjct: 677 SPPSNTSFKLVP--LSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
Query: 2316 LGVTQSLDRETKERFVLMITATDSGSP 2342
+ + + L++ +D G P
Sbjct: 735 ITLEEKPAPTDVGLHRLVVNISDLGYP 761
Score = 251 bits (641), Expect = 1e-65
Identities = 202/673 (30%), Positives = 315/673 (46%), Gaps = 51/673 (7%)
Query: 2245 VSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV-ARDDDRGSNSKLSYVLFGGN 2303
+ I++ D ND P+F ++++PEN TL + + A D D G N Y L G
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPEN--TLINSRFPIPSATDPDTGFNGVQHYELLNGQ 185
Query: 2304 EDNAFTLSASGE------LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDV 2357
+ + E L V Q+LDRE K+ +V+ I D G+P + T + V V DV
Sbjct: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
Query: 2358 NDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGG-------NSQFTI 2410
NDN P F IPE+AP GT V+ ++A+DAD NA IR I G F +
Sbjct: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
Query: 2411 NPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHP 2470
N +TG I LDRE + + V+ SD GS P + +V + VTDVNDNPP
Sbjct: 306 NNTTGLITVQRSLDREETAIHKVTVLASD-GSSTP--ARATVTINVTDVNDNPPNIDLRY 362
Query: 2471 YVT------HIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPL--RGAI 2522
++ ++ + + +TV+D D N ++ + FH+ + +
Sbjct: 363 IISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI--EREVPFHLKAVYDNQYL 420
Query: 2523 MAAGPL---NGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKV-RAKEQTFMFPE 2578
+ L G E +F + D G + V V+ ++ D P + E
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 2579 NQPVSSLVTTITGSSL-RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVV 2637
N +TTI+ + G+ G + F +D+ TG ++ S+ D E+ ++++
Sbjct: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
Query: 2638 WIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP---FISEILENLSPRKILTVSAMD 2694
+ ARD G PP S + +TVLD NDN+P F + F+SE L S ++TV+ D
Sbjct: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT--D 598
Query: 2695 KDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQS 2754
D+G N + I+N N ++F ++ +G I+S DRE+ S Y +K++D G P +S
Sbjct: 599 ADAGENKAVTLSILNDN--DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS 656
Query: 2755 TSVKVMINILDENDNAPRF----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYS 2810
++ KV IN++D NDN+P S VP ++ G V V D D G+NA +Y+
Sbjct: 657 STAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYT 716
Query: 2811 IMDASLP--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFV-TDIND 2867
I+ + F I+P TG+I + D +R+ V+ D G+ S + V +ND
Sbjct: 717 IVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVND 776
Query: 2868 NAPRFSRTSYYLD 2880
A SY D
Sbjct: 777 TA---GNASYIYD 786
Score = 248 bits (634), Expect = 8e-65
Identities = 230/765 (30%), Positives = 359/765 (46%), Gaps = 58/765 (7%)
Query: 1425 IFKSIVENIPIGT--SVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA 1482
I + + EN+PIG ++++ + + L Y ++ + + G I+T +
Sbjct: 30 IREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTS 89
Query: 1483 E-IDREFANLFELTVKAND-----QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALA 1536
IDRE + N+ + V + + L + I+V D NDN PMF S
Sbjct: 90 NRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINI 149
Query: 1537 ADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASALVPS 1593
+ P + +I S A DPD G NG YE++NG + IV+ G+ + +V
Sbjct: 150 SIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGE-KWPQLIVQQ 208
Query: 1594 QL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
L Y + + D G ++ ST L + + ++ PVF + + + E P+G
Sbjct: 209 NLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVG 268
Query: 1646 TNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACL 1704
T+VI + A + GS A + YI + T RLF + TG+I LDRE+ A +
Sbjct: 269 TSVIQLHATDADIGSNAEIR-YIFGAQVAPAT-KRLFALNNTTGLITVQRSLDREETA-I 325
Query: 1705 YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGDGSK 1758
+ V V A + S+ RA V I + D+NDNPP + + + E +K
Sbjct: 326 HKVTVLASDGSST---PARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 1759 IMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRR-LDRERRSKYSL-LVRA 1816
I +T D D N V I + ++ L+ T LD E ++S +V +
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 1817 DDGLQSSDMR--INITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNG 1874
D G S + + + + D ND+ P F++PV + E+ G + I ATD+DSG N
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 1875 EITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQ--FTTIRVYF 1932
+I Y + + F L+ TGV +R+ D E Q+ +I TV A D G + V
Sbjct: 503 DIVYQLGPN--ASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIV 560
Query: 1933 NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQF 1992
+LD NDN P F+ N + + ENLP STV V VTDAD G N +T SI + + F
Sbjct: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND--NF 618
Query: 1993 TVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+D +GV+K + DRE QS Y V+ D Q P S STA+V+I ++DVNDN P
Sbjct: 619 VLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS---STAKVTINVMDVNDNSPVV 675
Query: 2052 LSP----KLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDG 2104
+SP +P + +VV + A D D+G N+ ++YT+++ GN F I + G
Sbjct: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVS--GNNKGLFRIDPVTG 733
Query: 2105 EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDIND 2149
+ L + +V + L V +D G P S +V++ L +ND
Sbjct: 734 NITLEEKPAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVND 776
Score = 248 bits (633), Expect = 1e-64
Identities = 223/773 (28%), Positives = 357/773 (46%), Gaps = 63/773 (8%)
Query: 259 VPEDAVVGS--SVLQVAAADADEGTNADIRYRLQDEGTP---FQMDPETG-LITVREPLD 312
+PE+ +G+ L ++ +A GT+A + YRL + ++ TG + T +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 313 FE---ARRQYSLTVQAM-DRGVPSLTGRAEALIQLL----DVNDNDPVVKFRYFPATSRY 364
E A Y+ + + V L LI++ D NDN P+ FP+
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPM-----FPSPVIN 148
Query: 365 ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV----QSSKVPNLSLI 420
S+ EN + + + + TD D+ NG ++L G ++ + K P L
Sbjct: 149 ISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLI-- 205
Query: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
V LDRE+ +Y + + V D G P +SS A L + V+D+ND+ PVF +
Sbjct: 206 -VQQNLDREQKDTYVMKIKVEDG-GTPQ------KSSTAILQVTVSDVNDNRPVFKEGQV 257
Query: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI---VSGNGLGWFHISEHSGLVTTGSS 537
V++ E AP G+ V + ATD D G NA +RY V+ F ++ +GL+T S
Sbjct: 258 EVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRS 317
Query: 538 GGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFS-----QPEGYDVSV 592
LDRE + + + A D P + A + + + DVND P P V +
Sbjct: 318 --LDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNIDLRYIISPINGTVYL 373
Query: 593 VENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGR---LSTISSLDR 649
E P T++ ++ +D D NG V ++ F L V L T S LD
Sbjct: 374 SEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP----FHLKAVYDNQYLLETSSLLDY 429
Query: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYIT 709
E +S ++A+D G P + A + V L D NDN P+F + EN G Y+T
Sbjct: 430 EGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLT 489
Query: 710 TVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
T+SATD D G N + Y + + S F ++ ++GV++ DREE+ + + A D G
Sbjct: 490 TISATDEDSGKNADIVYQLGP-NASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNG 548
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYL 829
+QA V +TVLD DN P F+ + F V EN+ VG ++ + D N +
Sbjct: 549 TPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVT 608
Query: 830 ITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG---TVTGDTMVNITVKDL 886
++ + F ++ +G + + DRE+QS Y V A+ G + V I V D+
Sbjct: 609 LSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDV 668
Query: 887 NDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDEGVNGMVLYSL-KQNPKNLFAI 942
NDNSP + + + V + G + + AVD D G+N + Y++ N K LF I
Sbjct: 669 NDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRI 728
Query: 943 NEKNGTISL-LGPLDVHAGSYQIEILASDMGVPQ-LSSSVILTVYVHDVNDNS 993
+ G I+L P G +++ + SD+G P+ L + V++ +YV+D N+
Sbjct: 729 DPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNA 781
Score = 238 bits (607), Expect = 1e-61
Identities = 178/580 (30%), Positives = 285/580 (49%), Gaps = 34/580 (5%)
Query: 1696 LDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGD 1755
LDREQ Y++ + +E ++ A +++T+ D+NDN PVF +++ + EN
Sbjct: 210 LDREQKDT-YVMKI-KVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
Query: 1756 GSKIMQLTAMDADEGANALVTY----TIISGADDSFRIDPESGDLIATRRLDRERRSKYS 1811
G+ ++QL A DAD G+NA + Y + F ++ +G + R LDRE + +
Sbjct: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
Query: 1812 LLVRADDGLQS-SDMRINITVSDVNDHTPKFS-----RPVY-SFDIPEDTIPGSLVAAIL 1864
+ V A DG + + + I V+DVND+ P P+ + + E + +A I
Sbjct: 328 VTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
Query: 1865 ATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-- 1922
+D D+ VNG++ + + + + + + LLDYE + + + A D G
Sbjct: 388 VSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKP 447
Query: 1923 --GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT 1980
Q +RV + D NDNPPIF+ S+ EN G + + TD D G N+ +
Sbjct: 448 SLNQTALVRV--KLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIV 505
Query: 1981 YSIASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSI 2039
Y + G + F +D K GVL + DRE Q + V D P S A V +
Sbjct: 506 YQL--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPP---LQSQAAVIV 560
Query: 2040 ILLDVNDNPPTFLSPKLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFS 2098
+LD NDN P F ++ EN P + V TD D+G N + ++LN N F
Sbjct: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN-FV 619
Query: 2099 IGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIF---- 2154
+ G ++ DRE+ S+YT V ATD GQP SS+ +V + V+D+NDN+P+
Sbjct: 620 LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP 679
Query: 2155 AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVA 2214
+ +K+ + + + G+ + +VFA D D G N +++Y IV+GN FRID VTG IT+
Sbjct: 680 SNTSFKL-VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
Query: 2215 KPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDIND 2254
+ + L V +D G P++ T+ +V L +ND
Sbjct: 739 EKPAPTDVGLHRLVVNISDLG-YPKS-LHTLVLVFLYVND 776
Score = 206 bits (524), Expect = 5e-52
Identities = 178/695 (25%), Positives = 317/695 (45%), Gaps = 51/695 (7%)
Query: 2880 DCPELTEIGS--KVTQVFATDPDEGSNGQVFYFIKSQS---EYFRINATTGEIF--NKQI 2932
+ PE IG+ K + + G++ + Y + S++ +++++TGEIF + +I
Sbjct: 33 ELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRI 92
Query: 2933 LKYQNVTGFSNVNINRHSF----IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKY 2988
+ + G S N F ++ +D + I + D+NDNAP F
Sbjct: 93 DREKLCAGASYAEENECFFELEVVILPND-----FFRLIKIKIIVKDTNDNAPMFPSPVI 147
Query: 2989 FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLD-----NDTGW--I 3041
+ +N + ++ + + D D G N Y + N + F LD W +
Sbjct: 148 NISIPENTLINSRF-PIPSATDPDTGFNGVQHYELLNGQSV--FGLDIVETPEGEKWPQL 204
Query: 3042 SVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPES 3101
V +L + + + + +D G P SS A + +TV++ N + P F + + IPE+
Sbjct: 205 IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPEN 264
Query: 3102 HSIGSIVRTVSARDRDAAMNGLIKYSISSG---NEEGIFAINSSTGILTLAKALDYELCQ 3158
+G+ V + A D D N I+Y + + +FA+N++TG++T+ ++LD E
Sbjct: 265 APVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETA 324
Query: 3159 KHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL--ENAPSGTT 3212
H++T+ A DG + +VT+NV DVNDN P ++ TV E P T
Sbjct: 325 IHKVTVLASDGS--STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
Query: 3213 VIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAF 3271
+ + +D D+ N VI + + L + N ++ T LD+E + + + A
Sbjct: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 3272 NVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDG 3331
+ A V ++L+ N+ P F + +SE +G + + A+D D G +
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
Query: 3332 EVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTV 3391
++ Y + N+ F +++KTG + S + DRE++ER V A++ G+ + V
Sbjct: 503 DIVYQLGPNA--SFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQS--QAAV 558
Query: 3392 NVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNEN 3450
VTVLD ND P FT N + +SE +P + V ++ D+D+ + + N+N
Sbjct: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADA---GENKAVTLSILNDN 615
Query: 3451 GAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPML 3510
F ++P +G I DRE Y V A D G P + +A + + + D+NDN P++
Sbjct: 616 DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVV 675
Query: 3511 -----TVSEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
S V + PG++V + + D D N
Sbjct: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMN 710
Score = 197 bits (502), Expect = 2e-49
Identities = 196/673 (29%), Positives = 301/673 (44%), Gaps = 54/673 (8%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEE 3134
+ I V + N + P F ++ +IPE+ I S SA D D NG+ Y + +G
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSV 187
Query: 3135 -GIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ + + G L + + LD E + M I DGG ++ + V V DVND
Sbjct: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND 247
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYT----VQSSDSDLFVIDP 3245
N PVF + ENAP GT+VI L+ATDAD G+NA I Y V + LF ++
Sbjct: 248 NRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNN 307
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTN------EYVPRFV 3299
TG+IT Q LD E + +TV A + + T+N+ N Y+ +
Sbjct: 308 TTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPI 367
Query: 3300 SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
+ Y +SE P T + + SD+D +G+V I R+ F + Y+
Sbjct: 368 NGTVY--LSEKDPVNTKIALITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLE 422
Query: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
S +LD E + S K++A + G + + V V + D ND PPIF + + +SE
Sbjct: 423 TSSLLDYEGTKEFSFKIVASDSG--KPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
G ++T +SA D DS + + Y +G F ++ +TG +T + DRE
Sbjct: 481 NNRRGLYLTTISATDEDSGKN-ADIVYQLGPNAS--FFDLDRKTGVLTASRVFDREEQER 537
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
+ +V A D+GTP A+++VT+ D NDN P T + + V EN + V + T
Sbjct: 538 FIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT 597
Query: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
D D N+ LS F L +GV+ + DREQ + + V D G P
Sbjct: 598 DADAGENKA----VTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
Query: 3593 QMSSTGTVHITVIDQNDN------PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV--- 3643
SST V I V+D NDN P + + ++ + PG ++ V D D
Sbjct: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPL---SAIPGSVVAEVFAVDVDTGMN 710
Query: 3644 LDSFHCSLTSGVTSLFSIP--GGTCDLNSQPRSTD-GTFDLTV-LSNDGVHSTVTSNIRV 3699
+ + ++ LF I G L +P TD G L V +S+ G ++ + + V
Sbjct: 711 AELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLV 770
Query: 3700 FFAGFSNATVDNS 3712
F + N T N+
Sbjct: 771 FL--YVNDTAGNA 781
Score = 174 bits (442), Expect = 2e-42
Identities = 160/546 (29%), Positives = 254/546 (46%), Gaps = 44/546 (8%)
Query: 3098 IPESHSIGSIVRTVSARDRDAAMN---GLIKYSISSGNEEGIFAINSSTG-ILTLAKALD 3153
+PE+ IG+I + ++ +AA L+ +S + + ++SSTG I T + +D
Sbjct: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
Query: 3154 YE-LCQK----------HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 3202
E LC E+ + + + + + V D NDN+P+F S +
Sbjct: 94 REKLCAGASYAEENECFFELEVVILPNDFFR---LIKIKIIVKDTNDNAPMFPSPVINIS 150
Query: 3203 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGV----ITTQGFL 3256
+ EN + +ATD D+G N V Y + + S L +++ G + Q L
Sbjct: 151 IPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNL 210
Query: 3257 DFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTI 3316
D E K +Y + +K + ++ S A + + + N+ P F I E AP GT
Sbjct: 211 DREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTS 270
Query: 3317 VGEVFASDRDLGTDGEVHYLIFGN----SRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
V ++ A+D D+G++ E+ Y IFG + K+ F +N TG I V LDRE+ +
Sbjct: 271 VIQLHATDADIGSNAEIRY-IFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVT 329
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYS-----VQISEGVPIGTHVTFVS 3427
VLA + S VT+NVT ++ N P I I S V +SE P+ T + ++
Sbjct: 330 VLASDGSSTPARAT--VTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
Query: 3428 AFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGT 3487
D D+ + + FI ++ + ++ LD E ++ ++A DSG
Sbjct: 388 VSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGK 446
Query: 3488 PSATGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFT 3545
PS +A + V LED NDN P+ V E V EN R G + T+ +TD D N
Sbjct: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKN-ADIV 505
Query: 3546 YYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITV 3604
Y L GP S+F L GVL+ +R DRE+ F +V +D+G P + S V +TV
Sbjct: 506 YQL---GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTV 562
Query: 3605 IDQNDN 3610
+D+NDN
Sbjct: 563 LDENDN 568
Score = 129 bits (324), Expect = 7e-29
Identities = 129/475 (27%), Positives = 206/475 (43%), Gaps = 57/475 (12%)
Query: 3206 NAPSGTTVIHLNATDADSGTNAVIAYTVQSS--DSDLFVIDPNTG-VITTQGFLDFETKQ 3262
N P + H+NA +GT+A + Y + S D+ L + +TG + TT +D E
Sbjct: 42 NIPKDLNISHINAA---TGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREK-- 96
Query: 3263 SYHLTVKAFNVPDEERCSFAT--------------VNIQLKGTNEYVPRFVSKLYYFEIS 3308
+ +E C F + I +K TN+ P F S + I+
Sbjct: 97 ----LCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPV----IN 148
Query: 3309 EAAPKGTIVGEVF----ASDRDLGTDGEVHYLIFGNSRKKGFQI-----NKKTGQIYVSG 3359
+ P+ T++ F A+D D G +G HY + G I +K Q+ V
Sbjct: 149 ISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQ 208
Query: 3360 ILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVP 3418
LDRE+++ +K+ ++ G+ + + + VTV D ND P+F V I E P
Sbjct: 209 NLDREQKDTYVMKIKVEDGGTPQKSST--AILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
Query: 3419 IGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FSINPQTGQITVTAELDRETLPI 3475
+GT V + A D+D I S + Y G+ F++N TG ITV LDRE I
Sbjct: 267 VGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAI 325
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGP------MLTVSEGEV-MENKRP-GTLV 3527
+ ++VLA D + A + ++ VT D+NDN P +++ G V + K P T +
Sbjct: 326 HKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKI 383
Query: 3528 MTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTK 3587
+ +D D N G ++ P +L T+ +D E +F +V
Sbjct: 384 ALITVSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
Query: 3588 DSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPD 3642
DSG P ++ T V + + D+NDNP I ++ N G L ++ D D
Sbjct: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDED 497
Score = 57.8 bits (138), Expect = 3e-07
Identities = 81/333 (24%), Positives = 134/333 (40%), Gaps = 54/333 (16%)
Query: 3408 IYSV--QISEGVPIGT-----HVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTG 3460
IY++ ++ E VPIG +++ ++A S R + + ++ TG
Sbjct: 27 IYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL---VSKAGDAPLVKVSSSTG 83
Query: 3461 QITVTAE-LDRETLP-----------IYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP 3508
+I T+ +DRE L + L V+ + + + + ++D NDN P
Sbjct: 84 EIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAP 140
Query: 3509 MLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGV- 3565
M V + EN + +TDPD N G Y LL+ S F L
Sbjct: 141 MFPSPVINISIPENTLINSRFPIPSATDPDTGFN-GVQHYELLN---GQSVFGLDIVETP 196
Query: 3566 -------LSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVE 3618
L + +DREQ + + + +D G PQ SST + +TV D NDN + +
Sbjct: 197 EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQ 256
Query: 3619 IFVNYYGNLFPGGILGSVKPQDPDVLDS------FHCSLTSGVTSLFSIPGGTCDLNSQP 3672
+ V+ N G + + D D+ + F + LF++ T L +
Sbjct: 257 VEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL-NNTTGLITVQ 315
Query: 3673 RSTD----GTFDLTVLSNDG----VHSTVTSNI 3697
RS D +TVL++DG +TVT N+
Sbjct: 316 RSLDREETAIHKVTVLASDGSSTPARATVTINV 348
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 343 bits (881), Expect = 2e-93
Identities = 258/802 (32%), Positives = 391/802 (48%), Gaps = 58/802 (7%)
Query: 22 SQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFT-----YRLSE 76
S LL + LL+ PG A R V++V EEQPP TL+G++ GF Y+L
Sbjct: 41 SMLLALLLLLAPSPGHA------TRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEV 94
Query: 77 SHALFAINSSTGALYTTST-IDRESL-------PSDVINL--------VVLSSAPTYPTE 120
++ TG ++TT T IDRE L P D L +V + +P E
Sbjct: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRL-LE 153
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
++ V+D+NDN P F P I + E+++ G + A+D D G NGV SY + G
Sbjct: 154 GQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGV--ASYELQAGP 211
Query: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
EA + + E L+ G LDRE Y L ++V+D G P R + VTV
Sbjct: 212 EAQEL-FGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTV 270
Query: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP----F 296
D NDN P F Y+A + E++ +G SV+QV A D+D+G NA+I Y
Sbjct: 271 LDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLL 330
Query: 297 QMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFR 356
++D TGLITV+ P+D E +V A DRG + RA+ ++ + D+NDN P ++ R
Sbjct: 331 RLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR 390
Query: 357 YFPATSR---YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGG--NEQRHFEVQS 411
+ A++ E+ T VAL+ V+D D N ++ + G + R
Sbjct: 391 GIGLVTHQDGMANISEDVAEETAVALVQVSDRDE-GENAAVTCVVAGDVPFQLRQASETG 449
Query: 412 SKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDH 471
S ++ + LD E++ Y + + D+ G PP SS SL + V D+ND+
Sbjct: 450 SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPP------LSSTNSLKVQVVDVNDN 502
Query: 472 PPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI-VSGNGLGWFHISEHSG 530
PVF+Q V V E PG ++ I+A+D DSG NA L YS+ G F IS +G
Sbjct: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ +S LDRE L + A D+G A ++V +LD ND P F GY+
Sbjct: 563 EIQVKTS--LDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKF-MLSGYNF 619
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
SV+EN P + + M+ DGD G+N V+ S+ E D F + +G + + S DRE
Sbjct: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSV---EQDNGDFVIQNGTGTILSSLSFDRE 676
Query: 651 EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAH--IKENEPGGSYI 708
+Q+ Y+ + A D G PP+S+ + +++LD NDN+P +H + G +
Sbjct: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETV 736
Query: 709 TTVSATDPDLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD 767
+ V+A D D G N + YSI+ G+ FQ+ + SG I+ ++R ++L + +D
Sbjct: 737 SQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSD 796
Query: 768 GGNLQSPNQAIVTITVLDTQDN 789
G A+V + V +T N
Sbjct: 797 RGKPPRYGTALVHLYVNETLAN 818
Score = 290 bits (743), Expect = 2e-77
Identities = 229/764 (29%), Positives = 367/764 (48%), Gaps = 79/764 (10%)
Query: 287 YRLQDEGTPFQMDPETG-LITVREPLDFEARRQ---------------YSLTVQAMDRGV 330
Y+L+ ++D +TG + T +D E R+ S+T + G
Sbjct: 90 YKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSIT-DLVQNGS 148
Query: 331 PSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
P L E I++ D+NDN P F + ++ EN +G++ + +D D+
Sbjct: 149 PRLL---EGQIEVQDINDNTP-----NFASPVITLAIPENTNIGSLFPIPLASDRDA-GP 199
Query: 391 NGNISVQILGGNEQRHF------EVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNY 444
NG S ++ G E + E Q K P L V LDRER SY+LT+ V D
Sbjct: 200 NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLI---VMGNLDRERWDSYDLTIKVQDG- 255
Query: 445 GAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDS 504
G+PP R+S A L + V D ND+ P F + Y LSE +P G V + A D D
Sbjct: 256 GSPP------RASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ 309
Query: 505 GLNANLRYSIVSGNGL--GWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPK 562
G NA + Y+ + + ++GL+T G +DRE S + ++ A+D+G +PK
Sbjct: 310 GANAEIEYTFHQAPEVVRRLLRLDRNTGLITV--QGPVDREDLSTLRFSVLAKDRGTNPK 367
Query: 563 VSYAQLVVTLLDVNDEKPVF--------SQPEGYDVSVVENAPTGTELLMLRATDGDLGD 614
+ AQ+VVT+ D+ND P + +G ++ E+ T + +++ +D D G+
Sbjct: 368 SARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGM-ANISEDVAEETAVALVQVSDRDEGE 426
Query: 615 N--------GTVRFSLQEA-ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
N G V F L++A ET S + L T + LD E+ Y++ ++A D G
Sbjct: 427 NAAVTCVVAGDVPFQLRQASETGSDSKK----KYFLQTTTPLDYEKVKDYTIEIVAVDSG 482
Query: 666 SPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVK 725
+PP SS + V ++D+NDN+PVF EN G I ++A+D D G+N +
Sbjct: 483 NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELV 542
Query: 726 YSISAGDRSR--FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITV 783
YS+ ++ F ++ ++G I + +LDRE++ +Y+L++VA D G+ A V + V
Sbjct: 543 YSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNV 602
Query: 784 LDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQ 843
LD DN P F Y+F V EN+ VG V+ D N ++ G F I
Sbjct: 603 LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQN 662
Query: 844 VTGQLTTANVIDREEQSFY--QLKVVASGGTVTGDTMVNITVK--DLNDNSPHFLQAIES 899
TG + ++ DRE+QS Y QLK V GG V +T+ D NDN+P+ +
Sbjct: 663 GTGTILSSLSFDREQQSTYTFQLKAV-DGGVPPRSAYVGVTINVLDENDNAPYITAPSNT 721
Query: 900 VN--VVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK-QNPKNLFAINEKNGTISLLGPLD 956
+ + + G ++ Q A D D GVN ++YS+ NP LF I +G I+L ++
Sbjct: 722 SHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIE 781
Query: 957 -VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL 999
H G +++ + SD G P + ++ +YV++ N + + L
Sbjct: 782 RRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETL 825
Score = 290 bits (741), Expect = 3e-77
Identities = 224/688 (32%), Positives = 324/688 (47%), Gaps = 53/688 (7%)
Query: 963 QIEILASDM---GVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQ 1019
+ E+ +D+ G P+L I V D+NDN+P F + + E+ + S F
Sbjct: 135 EFEVSITDLVQNGSPRLLEGQI---EVQDINDNTPNFASPVITLAIPENTNIGSLFPIPL 191
Query: 1020 ASDKDSGANGEIAYTIAEG-NTGDAFGIF-------PDGQLYIKSELDRELQDRYVLMVV 1071
ASD+D+G NG +Y + G + FG+ QL + LDRE D Y L +
Sbjct: 192 ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIK 251
Query: 1072 ASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGP 1131
D P +++ + V + D NDN P F +Y E G V +V A D D G
Sbjct: 252 VQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGA 311
Query: 1132 NGEVRYSF----EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
N E+ Y+F E+V+ L +G IT DRE L R F+V+A D+G
Sbjct: 312 NAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLR------FSVLAKDRGT- 364
Query: 1188 QPLKDQATVHVYMKDINDNAPKF--------LKDFYQATISESAANLTQVLRVSASDVDE 1239
P +A V V +KD+NDNAP A ISE A T V V SD DE
Sbjct: 365 NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDE 424
Query: 1240 GNNGLIHYSIIKGNEERQFAIDSTSGQ-------VTLIGKLDYEATPAYSLVIQAVDSGT 1292
G N + ++ G+ Q S +G + LDYE Y++ I AVDSG
Sbjct: 425 GENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGN 483
Query: 1293 IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYY 1352
PL+ST +L + ++D NDN P F +S V EN + GE+++ +TA+D+DSG NA+L Y
Sbjct: 484 PPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVY 543
Query: 1353 SI-TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
S+ G F+ISP TG I + LD E + Y+L + A D+G P T +V+++V
Sbjct: 544 SLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVL 603
Query: 1412 DFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
D NDN P F S++EN+P + V VT D D N Q+ ++ Q F I
Sbjct: 604 DCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD---NGDFVI 660
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
GTI ++ DRE + + +KA D VP R A VTI V D NDN P +
Sbjct: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVP---PRSAYVGVTINVLDENDNAPYITA 717
Query: 1532 QNALA---ADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVA 1587
+ + P +G ++ + A D D G N E+ Y I G+ F + +SG + +
Sbjct: 718 PSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLE 777
Query: 1588 SALVPSQL-IYNLIVSATDLGPERRKST 1614
+ ++ L+V +D G R T
Sbjct: 778 KEIERRHHGLHRLVVKVSDRGKPPRYGT 805
Score = 284 bits (726), Expect = 2e-75
Identities = 222/762 (29%), Positives = 351/762 (46%), Gaps = 58/762 (7%)
Query: 698 IKENEPGGSYITTVSATD--PDLGTNGTVKYSISAGDRSRFQVNAQSG-VISTRMALDRE 754
+ E +P + I +++A PD+G Y + G +V+ ++G + +T ++DRE
Sbjct: 64 VPEEQPPNTLIGSLAADYGFPDVGH----LYKLEVG-APYLRVDGKTGDIFTTETSIDRE 118
Query: 755 -----------EKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVF 803
+ + ++ TD SP I V D DN P F+ + +
Sbjct: 119 GLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIP 178
Query: 804 ENVALGYHVGSVSASTMDLNSN--ISYLITTGDQ-KGMFAIN------QVTGQLTTANVI 854
EN +G AS D N SY + G + + +F + + QL +
Sbjct: 179 ENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNL 238
Query: 855 DREEQSFYQLKV-VASGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHS 911
DRE Y L + V GG+ ++ +TV D NDN+P F + + EN GHS
Sbjct: 239 DRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHS 298
Query: 912 IFQAKAVDPDEGVNGMVLYSLKQNP---KNLFAINEKNGTISLLGPLDVH-AGSYQIEIL 967
+ Q KA D D+G N + Y+ Q P + L ++ G I++ GP+D + + +L
Sbjct: 299 VIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVL 358
Query: 968 ASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVT--------LSESEPVNSRFFKVQ 1019
A D G S+ + V V D+NDN+P + + +SE + VQ
Sbjct: 359 AKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQ 418
Query: 1020 ASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ-------LYIKSELDRELQDRYVLMVVA 1072
SD+D G N + +A G L + LD E Y + +VA
Sbjct: 419 VSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVA 478
Query: 1073 SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPN 1132
D PLS+T ++ V + DVNDN P+F + F E + G + +++A D D G N
Sbjct: 479 VDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
Query: 1133 GEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD 1192
E+ YS E L IS E T + ++ + R + V+A D+G P L+
Sbjct: 539 AELVYSLEPEPAAKGLFTISPE---TGEIQVKTSLDREQRESYELKVVAADRGSPS-LQG 594
Query: 1193 QATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKG 1252
ATV V + D NDN PKF+ Y ++ E+ L+ V V+ D D+G N + S+ +
Sbjct: 595 TATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD 654
Query: 1253 NEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNT 1312
N + F I + +G + D E Y+ ++AVD G P ++ + I++LDENDN
Sbjct: 655 NGD--FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNA 712
Query: 1313 P--SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG 1370
P + P +T + R+GE VS V A D DSG NA+L YSI G N +G F I ++G
Sbjct: 713 PYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSG 772
Query: 1371 SIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
+I L K+++ L++L + D+G+PPR T V ++V +
Sbjct: 773 AITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNE 814
Score = 276 bits (705), Expect = 5e-73
Identities = 213/674 (31%), Positives = 322/674 (47%), Gaps = 53/674 (7%)
Query: 2018 VQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATD 2076
V + DL Q + R + I + D+NDN P F SP +T IPENT I ++ A+D
Sbjct: 138 VSITDLVQNGSPRLL---EGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASD 194
Query: 2077 PDSGPNSYIEYTL-LNPLGNK-FSIGTIDGEVR------LTGELDREEVSNYTLTVVATD 2128
D+GPN Y L P + F + + + + G LDRE +Y LT+ D
Sbjct: 195 RDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQD 254
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P +SS + V VLD NDN P F + Y+ E++EN+ G +IQV A D D+G N +
Sbjct: 255 GGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAE 314
Query: 2189 VRYGIVNGN--TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVS 2246
+ Y + R+D TG ITV P+DRE T +V A DRG+ P++ + V
Sbjct: 315 IEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
Query: 2247 IVLLDINDFVPVFELSPYSV--------NVPENLGTLPRTILQVVARDDDRGSNSKLSYV 2298
+ + D+ND P E+ + N+ E++ L V+ D D G N+ ++ V
Sbjct: 375 VTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS-DRDEGENAAVTCV 433
Query: 2299 LFGGNEDNAFTLSASGELG----------VTQSLDRETKERFVLMITATDSGSPALTGTG 2348
+ G D F L + E G T LD E + + + I A DSG+P L+ T
Sbjct: 434 VAG---DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN 490
Query: 2349 TINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII-----G 2403
++ V V DVNDN P F PE+ G + + ASDAD+ NA +
Sbjct: 491 SLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA 550
Query: 2404 GNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNP 2463
FTI+P TG+I LDRE +++Y L VV +D GSP L + +VLV V D NDN
Sbjct: 551 AKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPS-LQGTATVLVNVLDCNDND 609
Query: 2464 PRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIM 2523
P+F Y + S V VTV D D G N+++ S+ N + F I G I+
Sbjct: 610 PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTIL 668
Query: 2524 AAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQT---FMFP 2577
++ + + T++ +K DGG P++ VT+ +++ D P + A T + P
Sbjct: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
Query: 2578 EN---QPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQK 2634
+ + VS + S + E + Y IA GN FQI +G +++ + ++
Sbjct: 729 QTRLGETVSQVAAEDFDSGVNAE-LIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
Query: 2635 YVVWIEARDGGFPP 2648
+ + ++ D G PP
Sbjct: 788 HRLVVKVSDRGKPP 801
Score = 274 bits (701), Expect = 1e-72
Identities = 216/706 (30%), Positives = 326/706 (46%), Gaps = 55/706 (7%)
Query: 1788 RIDPESGDLIATRR-LDRERRSKYSLLVRAD-----------DGLQSSDMRI---NITVS 1832
R+D ++GD+ T +DRE + + D D +Q+ R+ I V
Sbjct: 100 RVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQ 159
Query: 1833 DVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLN 1892
D+ND+TP F+ PV + IPE+T GSL LA+D D+G NG +Y + E F
Sbjct: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGL 219
Query: 1893 PITG-------VFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVYFNILDVNDNPPI 1943
+ + LD E Y LT++ +DGG + ++ + +LD NDN P
Sbjct: 220 QVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPK 279
Query: 1944 FSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ--FTVDKN-GVL 2000
F SY L EN P+G +V+ D+D G N+++ Y+ + + +D+N G++
Sbjct: 280 FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLI 339
Query: 2001 KVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFL-------- 2052
V +DRE S V D P S + AQV + + D+NDN PT
Sbjct: 340 TVQGPVDREDLSTLRFSVLAKDRGTNPKS---ARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
Query: 2053 -SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE------ 2105
+ I E+ +T V Q +D D G N+ + + + + + G
Sbjct: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
Query: 2106 -VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEIN 2164
++ T LD E+V +YT+ +VA D G P LSS+ + V V+D+NDN P+F Q++ +V
Sbjct: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGI-VNGNTNQEFRIDSVTGAITVAKPLDREKTP 2223
EN G I ++ A+D D G+N ++ Y + F I TG I V LDRE+
Sbjct: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
Query: 2224 TYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV 2283
+Y L V A DRGS T+TV + +LD ND P F LS Y+ +V EN+ L + V
Sbjct: 577 SYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL-SPVGMVT 635
Query: 2284 ARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPA 2343
D D+G N+++ + N D + +G + + S DRE + + + A D G P
Sbjct: 636 VIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPP 694
Query: 2344 LTGTGTINVIVDDVNDNVP--TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA--VI 2399
+ + + V D NDN P T S + G V V A D D+ NA +
Sbjct: 695 RSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIY 754
Query: 2400 RIIGGN--SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSP 2443
I GGN F I +G I ++R + LVV SD G P
Sbjct: 755 SIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
Score = 273 bits (698), Expect = 3e-72
Identities = 215/727 (29%), Positives = 338/727 (46%), Gaps = 56/727 (7%)
Query: 1719 PRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYT 1778
PR ++E+ QDINDN P F + ++ L + EN GS A D D G N + +Y
Sbjct: 149 PRLLEGQIEV--QDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
Query: 1779 IISG--ADDSFRI------DPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRI 1827
+ +G A + F + + + LI LDRER Y L ++ DG ++S +
Sbjct: 207 LQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALL 266
Query: 1828 NITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDE-- 1885
+TV D ND+ PKF RP Y ++ E++ G V + A D D G N EI Y ++ E
Sbjct: 267 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVV 326
Query: 1886 DGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIR--VYFNILDVNDNPPI 1943
+ L+ TG+ + +D E +V A+D G + R V + D+NDN P
Sbjct: 327 RRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPT 386
Query: 1944 FSLNSYS--------TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD 1995
+ ++ E++ + V + V+D D+G N+ +T +A
Sbjct: 387 IEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS 446
Query: 1996 KNG-------VLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNP 2048
+ G L+ LD E Y + + D P S ST + + ++DVNDN
Sbjct: 447 ETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLS---STNSLKVQVVDVNDNA 503
Query: 2049 PTFL-SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--FSIGTIDGE 2105
P F S PEN V+ + A+D DSG N+ + Y+L K F+I GE
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 2106 VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINE 2165
+++ LDRE+ +Y L VVA D+G PSL + V+V VLD NDN+P F + Y + E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 2166 NTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTY 2225
N + + V DGD+G N QV+ + N +F I + TG I + DRE+ TY
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--DFVIQNGTGTILSSLSFDREQQSTY 681
Query: 2226 HLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL---SPYSVNVPENLGTLPRTILQV 2282
++A D G PR+ V+I +LD ND P + + + P+ L T+ QV
Sbjct: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQT--RLGETVSQV 739
Query: 2283 VARDDDRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGS 2341
A D D G N++L Y + GGN F + S SG + + + ++R L++ +D G
Sbjct: 740 AAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGK 799
Query: 2342 PALTGTGTINVIVDDVNDNVPTFASKAYF-TTIPEDAPTGTDVLLVNASDADASK---NA 2397
P GT +++ V++ T A++ T + T D+ + + + SK N
Sbjct: 800 PPRYGTALVHLYVNE------TLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNI 853
Query: 2398 VIRIIGG 2404
+ ++ G
Sbjct: 854 LFGVVAG 860
Score = 260 bits (665), Expect = 2e-68
Identities = 197/663 (29%), Positives = 309/663 (46%), Gaps = 31/663 (4%)
Query: 2657 ITVLDVNDNAPIFKEDPFISEILENLSPRKILTVS-AMDKDSGPNGQLDYEIVNG-NMEN 2714
I V D+NDN P F I EN + + + A D+D+GPNG YE+ G +
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 2715 SFSINHATGEIRS------VRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDEND 2768
F + A + + LDRE+ Y LTIK D GSP +++S + + +LD ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 2769 NAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDA----SLPFTINPS 2823
NAP+F + + A + ENSP+G++V +V +D D G NA Y+ A ++ +
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
Query: 2824 TGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDINDNAPRFSRTSYYL- 2879
TG I + P++RED R V A D G + V + V D+NDNAP L
Sbjct: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
Query: 2880 -------DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQI 2932
+ E + V V +D DEG N V + + A+ +K+
Sbjct: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKK 455
Query: 2933 LKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPV 2992
Q T + ++ + + D G P L S ++ + +VD NDNAP F +S
Sbjct: 456 YFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF 515
Query: 2993 TKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHL-GKFKLDNDTGWISVASSLISDL 3051
+N K G + +TA D D G N+E+ Y + + G F + +TG I V +SL +
Sbjct: 516 PENNKPGEVIAEITA-SDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQ 574
Query: 3052 NQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
+++ + V A D+G+P L ATV + V + N + P+F S + ++ E+ S V V
Sbjct: 575 RESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMV 634
Query: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
+ D D N ++ S+ N G F I + TG + + + D E + + A+DGG
Sbjct: 635 TVIDGDKGENAQVQLSVEQDN--GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGV 692
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFL--SDDYFPTVLENAPSGTTVIHLNATDADSGTNAVI 3229
R+ Y VT+NV+D NDN+P S+ + G TV + A D DSG NA +
Sbjct: 693 PPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAEL 752
Query: 3230 AYTVQSSDS-DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
Y++ + LF I ++G IT + ++ + L VK + R A V++ +
Sbjct: 753 IYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
Query: 3289 KGT 3291
T
Sbjct: 813 NET 815
Score = 260 bits (664), Expect = 3e-68
Identities = 212/669 (31%), Positives = 298/669 (44%), Gaps = 47/669 (7%)
Query: 2124 VVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDE 2183
V TD Q E + V DINDN P FA + + I ENT G+ A+D D
Sbjct: 138 VSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDA 197
Query: 2184 GTNGQVRYGIVNGNTNQEF-------RIDSVTGAITVAKPLDREKTPTYHLTVQATDRGS 2236
G NG Y + G QE + + V LDRE+ +Y LT++ D GS
Sbjct: 198 GPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGS 257
Query: 2237 TPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLS 2296
PR ++ + + +LD ND P FE Y + EN + +++QV A D D+G+N+++
Sbjct: 258 PPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN-SPIGHSVIQVKANDSDQGANAEIE 316
Query: 2297 YVLFGGNEDNAFTLSA---SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVI 2353
Y E L +G + V +DRE + A D G+ + + V
Sbjct: 317 YTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVT 376
Query: 2354 VDDVNDNVPTFASKAY--------FTTIPEDAPTGTDVLLVNASDADASKNAVIR-IIGG 2404
V D+NDN PT + I ED T V LV SD D +NA + ++ G
Sbjct: 377 VKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG 436
Query: 2405 NSQFTINPS--TGQ-------IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
+ F + + TG + T+ LD E +YT+ +V D+G+P PLSS+ S+ V
Sbjct: 437 DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNP-PLSSTNSLKVQ 495
Query: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEK--F 2513
V DVNDN P F P PG + +T +DAD G N+EL YSL + K F
Sbjct: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
Query: 2514 HIDPLRGAIMAAGPLNGASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKAD-FPKVRAK 2570
I P G I L+ ++ + V D GS + TV V ++ D PK
Sbjct: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLS 615
Query: 2571 EQTFMFPENQPVSS---LVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPL 2627
F EN P S +VT I G +GE ++ F I TG + S
Sbjct: 616 GYNFSVMENMPALSPVGMVTVIDGD--KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSF 673
Query: 2628 DFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR-- 2685
D E+ Y ++A DGG PP S+Y + I VLD NDNAP S L L+P+
Sbjct: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL--LTPQTR 731
Query: 2686 ---KILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLT 2742
+ V+A D DSG N +L Y I GN F I +G I + ++R + L
Sbjct: 732 LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
Query: 2743 IKSSDKGSP 2751
+K SD+G P
Sbjct: 792 VKVSDRGKP 800
Score = 259 bits (662), Expect = 5e-68
Identities = 237/745 (31%), Positives = 342/745 (45%), Gaps = 73/745 (9%)
Query: 2276 PRTILQVVARD---DDRGSNSKLS----YVLFGGNEDNAFTLSASGEL-GVTQSLDRETK 2327
P T++ +A D D G KL Y+ G + FT S + G+ + ++
Sbjct: 70 PNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPG 129
Query: 2328 ERFVLM--ITATD---SGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTD 2382
+ +L ++ TD +GSP L G I V D+NDN P FAS IPE+ G+
Sbjct: 130 DPCILEFEVSITDLVQNGSPRLL-EGQIEV--QDINDNTPNFASPVITLAIPENTNIGSL 186
Query: 2383 VLLVNASDADASKNAVI-----------RIIGGNSQFTINPSTGQIITSALLDRETKDNY 2431
+ ASD DA N V + G Q+I LDRE D+Y
Sbjct: 187 FPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSY 246
Query: 2432 TLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVT 2491
L + D GSP P +SS + VTV D NDN P+F+ Y + + G V V
Sbjct: 247 DLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKAN 305
Query: 2492 DADIGPNSELHYSLSGRNS---EKFHIDPLRGAIMAAGPLN--GASEVTFSVHVKDGGSF 2546
D+D G N+E+ Y+ +D G I GP++ S + FSV KD G+
Sbjct: 306 DSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTN 365
Query: 2547 PKTDSTTVTVRFVNKAD-FPKVRAK------EQTFMFPENQPVSS-LVTTITGSSLRGEP 2598
PK+ V V + D P + + Q M ++ V+ + S R E
Sbjct: 366 PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEG 425
Query: 2599 MSYYIASGNLGNT-FQIDQLTGQVSISQ---------PLDFEKIQKYVVWIEARDGGFPP 2648
+ + G+ FQ+ Q + S S+ PLD+EK++ Y + I A D G PP
Sbjct: 426 ENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPP 485
Query: 2649 FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILT-VSAMDKDSGPNGQLDYEI 2707
SS L + V+DVNDNAP+F + EN P +++ ++A D DSG N +L Y +
Sbjct: 486 LSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL 545
Query: 2708 -VNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDE 2766
+ F+I+ TGEI+ LDRE+ Y L + ++D+GSPS + V++N+LD
Sbjct: 546 EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDC 605
Query: 2767 NDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTG 2825
NDN P+F ++ V EN P V VT D D G NA + S+ + F I TG
Sbjct: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTG 665
Query: 2826 DIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRF---SRTSYYL 2879
I+ S +RE Y ++ A D G + VTI V D NDNAP S TS+ L
Sbjct: 666 TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL 725
Query: 2880 DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEY--FRINATTGEI-FNKQILKYQ 2936
P+ T +G V+QV A D D G N ++ Y I + Y F+I + +G I K+I +
Sbjct: 726 LTPQ-TRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRH 784
Query: 2937 NVTGFSNVNINRHSFIVTSSDRGKP 2961
+ H +V SDRGKP
Sbjct: 785 H---------GLHRLVVKVSDRGKP 800
Score = 238 bits (607), Expect = 1e-61
Identities = 198/680 (29%), Positives = 301/680 (44%), Gaps = 53/680 (7%)
Query: 219 LVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADAD 278
+ ++ G P+ L+ + VQDINDN P F S +PE+ +GS A+D D
Sbjct: 140 ITDLVQNGSPR---LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRD 196
Query: 279 EGTNADIRYRLQDEGTPFQM---------DPETGLITVREPLDFEARRQYSLTVQAMDRG 329
G N Y LQ ++ + + + V LD E Y LT++ D G
Sbjct: 197 AGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGG 256
Query: 330 VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPA 389
P A + +LD NDN P F S A + EN+ +G V + D+D
Sbjct: 257 SPPRASSALLRVTVLDTNDNAPK-----FERPSYEAELSENSPIGHSVIQVKANDSDQ-G 310
Query: 390 ANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPG 449
AN I E ++ + N LI V +DRE + + +V D P
Sbjct: 311 ANAEIEYTFHQAPEVVRRLLRLDR--NTGLITVQGPVDREDLSTLRFSVLAKDRGTNP-- 366
Query: 450 AAVQARSSVASLVIFVNDINDHPPVF--------SQQVYRVNLSEEAPPGSYVSGISATD 501
+S+ A +V+ V D+ND+ P + Q N+SE+ + V+ + +D
Sbjct: 367 -----KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSD 421
Query: 502 GDSGLNANLRYSIVSGNGLGWFHISEHSG--------LVTTGSSGGLDRELASQIVLNIS 553
D G NA + +V+G+ + +G L TT LD E + I
Sbjct: 422 RDEGENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIV 477
Query: 554 ARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLG 613
A D G P S L V ++DVND PVF+Q +V+ EN G + + A+D D G
Sbjct: 478 AVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVT-EVAFPENNKPGEVIAEITASDADSG 536
Query: 614 DNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMA 673
N + +SL+ + F + P +G + +SLDRE++ Y L V+A D GSP A
Sbjct: 537 SNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTA 596
Query: 674 RINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR 733
+ V++LD NDN P F Y + EN P S + V+ D D G N V+ S+ D
Sbjct: 597 TVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQ-DN 655
Query: 734 SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVF 793
F + +G I + ++ DRE+++ Y Q+ A DGG VTI VLD DN P
Sbjct: 656 GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYI 715
Query: 794 SQVAYSF--VVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLT 849
+ + + ++ LG V V+A D +N+ + Y I G+ G+F I +G +T
Sbjct: 716 TAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAIT 775
Query: 850 TANVIDREEQSFYQLKVVAS 869
I+R ++L V S
Sbjct: 776 LEKEIERRHHGLHRLVVKVS 795
Score = 236 bits (601), Expect = 6e-61
Identities = 201/691 (29%), Positives = 313/691 (45%), Gaps = 46/691 (6%)
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 2919
I V DINDN P F+ L PE T IGS A+D D G NG Y +++ E
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPE--- 212
Query: 2920 INATTGEIFNKQILKYQN-----VTGFSNVNINR---HSFIVTSSDRGKPSLISETTVTI 2971
E+F Q+ + Q + N++ R + + D G P S + +
Sbjct: 213 ----AQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
Query: 2972 NIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK 3031
++D+NDNAP+F + Y +++N +G +I+V A +D D G N+E+EY + +
Sbjct: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKA-NDSDQGANAEIEYTFHQAPEVVR 327
Query: 3032 --FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 3089
+LD +TG I+V + + +V AKD+G P S++A V +TV + N + P
Sbjct: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
Query: 3090 S------QSHMS--ATIPESHSIGSIVRTVSARDRDAAMN--------GLIKYSISSGNE 3133
+H A I E + + V V DRD N G + + + +E
Sbjct: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
Query: 3134 EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV 3193
G + + L LDYE + + + I A+D G + S+ V V+DVNDN+PV
Sbjct: 448 TG--SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
Query: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGVIT 3251
F EN G + + A+DADSG+NA + Y+++ + LF I P TG I
Sbjct: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ 565
Query: 3252 TQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAA 3311
+ LD E ++SY L V A + ATV + + N+ P+F+ Y F + E
Sbjct: 566 VKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM 625
Query: 3312 PKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSL 3371
P + VG V D D G + +V + F I TG I S DRE++ +
Sbjct: 626 PALSPVGMVTVIDGDKGENAQVQLSV--EQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 3372 KVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTL--NIYSVQISEGVPIGTHVTFVSA 3428
++ A + G + VT+NV LD ND P T N ++ +G V+ V+A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINV--LDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
Query: 3429 FDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTP 3488
D DS + + Y I GN G F I +G IT+ E++R ++ L V D G P
Sbjct: 742 EDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
Query: 3489 SATGSASLLVTLEDINDNGPMLTVSEGEVME 3519
G+A + + + + N +L G ++
Sbjct: 801 PRYGTALVHLYVNETLANRTLLETLLGHSLD 831
Score = 233 bits (593), Expect = 5e-60
Identities = 182/675 (26%), Positives = 306/675 (45%), Gaps = 54/675 (8%)
Query: 2761 INILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM---DASL 2816
I + D NDN P F S + + +PEN+ +G SD D G N ++ Y + +A
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 2817 PFTINPSTGD------IVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDIND 2867
F + + +++ L+RE D Y + + D G S + + V D ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 2868 NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEI 2927
NAP+F R SY + E + IG V QV A D D+G+N ++ Y E R
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVR-------- 327
Query: 2928 FNKQILKYQNVTGFSNV-------NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
++L+ TG V +++ F V + DRG + V + + D NDNA
Sbjct: 328 ---RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNA 384
Query: 2981 PQF--------LKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKF 3032
P ++++V T + + + D+D G N+ V ++ D +
Sbjct: 385 PTIEIRGIGLVTHQDGMANISEDVAEETA-VALVQVSDRDEGENAAVTCVVAGDVPF-QL 442
Query: 3033 KLDNDTG-------WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 3085
+ ++TG ++ + L + +++ I + A D GNPPLSS ++ + V + N +
Sbjct: 443 RQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDN 502
Query: 3086 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS-SGNEEGIFAINSSTG 3144
P F+QS PE++ G ++ ++A D D+ N + YS+ +G+F I+ TG
Sbjct: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
+ + +LD E + +E+ + A D G + G +V VNV+D NDN P F+ Y +V+
Sbjct: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVM 622
Query: 3205 ENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSY 3264
EN P+ + V + D D G NA + +V+ + D FVI TG I + D E + +Y
Sbjct: 623 ENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTY 681
Query: 3265 HLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFV--SKLYYFEISEAAPKGTIVGEVFA 3322
+KA + R ++ V I + N+ P S + ++ G V +V A
Sbjct: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
Query: 3323 SDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKE--ERVSLKVLAKNFGS 3380
D D G + E+ Y I G + FQI +G I + ++R R+ +KV +
Sbjct: 742 EDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPP 801
Query: 3381 IRGADIDEVTVNVTV 3395
G + + VN T+
Sbjct: 802 RYGTALVHLYVNETL 816
Score = 224 bits (570), Expect = 2e-57
Identities = 219/771 (28%), Positives = 334/771 (43%), Gaps = 92/771 (11%)
Query: 1539 PSAVIGSVLTTIMAAD---PDEGANGEIE----YEIINGDTDTFIVDRYSGD---LRVAS 1588
P+ +IGS +AAD PD G ++E Y ++G T S D LR
Sbjct: 70 PNTLIGS-----LAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQ 124
Query: 1589 ALVPSQ-LIYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
+P I VS TDL E I +Q ++ P F P + E IG
Sbjct: 125 NQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIG 184
Query: 1646 TNVISIEAASPR--------------GSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQ 1691
+ + I AS R G EA + + +E+ +L +G
Sbjct: 185 S-LFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGN------ 237
Query: 1692 TAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEE 1751
LDRE+ L ++ + PR A + +T+ D NDN P F + + E
Sbjct: 238 ----LDRERWDSYDLT--IKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSE 291
Query: 1752 NIGDGSKIMQLTAMDADEGANALVTYTIISGAD---DSFRIDPESGDLIATRRLDRERRS 1808
N G ++Q+ A D+D+GANA + YT + R+D +G + +DRE S
Sbjct: 292 NSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLS 351
Query: 1809 KYSLLVRADD---GLQSSDMRINITVSDVNDHTPKFSRPVYSF--------DIPEDTIPG 1857
V A D +S+ ++ +TV D+ND+ P +I ED
Sbjct: 352 TLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEE 411
Query: 1858 SLVAAILATDDDSGVNGEITYIVNED-------------DEDGIFFLNPITGVFNLTRLL 1904
+ VA + +D D G N +T +V D D +FL T L
Sbjct: 412 TAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTP-------L 464
Query: 1905 DYEVQQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGST 1962
DYE + Y + + A D G +T + ++DVNDN P+F+ + + EN G
Sbjct: 465 DYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEV 524
Query: 1963 VLVFNVTDADDGINSQLTYSIASGDSL-GQFTVD-KNGVLKVLKALDRESQSFYNLVVQV 2020
+ +DAD G N++L YS+ + G FT+ + G ++V +LDRE + Y L V
Sbjct: 525 IAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVA 584
Query: 2021 HDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDS 2079
D P+ + T+T V++ LD NDN P F+ + + EN P + V D D
Sbjct: 585 ADRGS-PSLQGTATVLVNV--LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDK 641
Query: 2080 GPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTE 2139
G N+ ++ ++ G+ F I G + + DRE+ S YT + A D G P S+
Sbjct: 642 GENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG 700
Query: 2140 VVVMVLDINDNNPIF---AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNG 2196
V + VLD NDN P + +K+ + T G + QV A D D G N ++ Y I G
Sbjct: 701 VTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGG 759
Query: 2197 NTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
N F+I S +GAIT+ K ++R + L V+ +DRG PR T+ V +
Sbjct: 760 NPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
Score = 213 bits (542), Expect = 4e-54
Identities = 192/745 (25%), Positives = 306/745 (41%), Gaps = 55/745 (7%)
Query: 2899 PDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQ-------ILKYQNVTGFSNVNINRHSF 2951
PD G Y ++ + Y R++ TG+IF + + + QN +
Sbjct: 84 PDVGH----LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVS 139
Query: 2952 IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDK 3011
I G P L+ I + D NDN P F + +N +G+ L + D+
Sbjct: 140 ITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGS-LFPIPLASDR 195
Query: 3012 DFGLNSEVEYFIS---NDNHLGKFKLDNDTG----WISVASSLISDLNQNFFITVTAKDK 3064
D G N Y + L ++ D + V +L + ++ +T+ +D
Sbjct: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDG 255
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLI 3124
G+PP +S A + +TV + N + P+F + A + E+ IG V V A D D N I
Sbjct: 256 GSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEI 315
Query: 3125 KYSISSGNE--EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTV 3182
+Y+ E + ++ +TG++T+ +D E ++ A D G ++ V V
Sbjct: 316 EYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVV 375
Query: 3183 NVIDVNDNSPVF--------LSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQ 3234
V D+NDN+P D + E+ T V + +D D G NA + V
Sbjct: 376 TVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVA 435
Query: 3235 SSDSDLFVIDPNTG-------VITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQ 3287
TG + T LD+E + Y + + A + + S ++ +Q
Sbjct: 436 GDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQ 495
Query: 3288 LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-F 3346
+ N+ P F + E G ++ E+ ASD D G++ E+ Y + KG F
Sbjct: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
Query: 3347 QINKKTGQIYVSGILDREKEERVSLKVLAKNFGS--IRGADIDEVTVNVTVLDAND-PPI 3403
I+ +TG+I V LDRE+ E LKV+A + GS ++G TV V VLD ND P
Sbjct: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT----ATVLVNVLDCNDNDPK 611
Query: 3404 FTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQIT 3463
F L+ Y+ + E +P + V V+ D D + +NG F I TG I
Sbjct: 612 FMLSGYNFSVMENMPALSPVGMVTVIDGDK---GENAQVQLSVEQDNGDFVIQNGTGTIL 668
Query: 3464 VTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT----VSEGEVME 3519
+ DRE Y + AVD G P + + + + D NDN P +T S +
Sbjct: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
Query: 3520 NKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIAD 3579
R G V + + D D N Y + P + S +G ++ +EI+R
Sbjct: 729 QTRLGETVSQVAAEDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
Query: 3580 FYLSVVTKDSGVPQMSSTGTVHITV 3604
L V D G P T VH+ V
Sbjct: 788 HRLVVKVSDRGKPPRYGTALVHLYV 812
Score = 209 bits (532), Expect = 6e-53
Identities = 173/565 (30%), Positives = 270/565 (47%), Gaps = 40/565 (7%)
Query: 3077 ITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNE-EG 3135
I V + N +TP F+ ++ IPE+ +IGS+ A DRDA NG+ Y + +G E +
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 3136 IFAINSSTGI------LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
+F + + L + LD E +++TI DGG R + V V+D ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS---DLFVIDPN 3246
N+P F Y + EN+P G +VI + A D+D G NA I YT + L +D N
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
Query: 3247 TGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVP----RFVSKL 3302
TG+IT QG +D E + +V A + + + A V + +K N+ P R + +
Sbjct: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
Query: 3303 YYFE----ISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI---------N 3349
+ + ISE + T V V SDRD G + V ++ G+ FQ+ +
Sbjct: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVP---FQLRQASETGSDS 452
Query: 3350 KKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNI 3408
KK + + LD EK + +++++A + G+ + + ++ V V+D ND P+FT ++
Sbjct: 453 KKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN--SLKVQVVDVNDNAPVFTQSV 510
Query: 3409 YSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAEL 3468
V E G + ++A D+DS + G F+I+P+TG+I V L
Sbjct: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
Query: 3469 DRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP--MLTVSEGEVMENKRPGTL 3526
DRE Y L V+A D G+PS G+A++LV + D NDN P ML+ VMEN +
Sbjct: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
Query: 3527 VMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVV 3585
V + D D +G LS F + G + ++ DREQ + + +
Sbjct: 631 VGMVTVIDGD----KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLK 686
Query: 3586 TKDSGVPQMSSTGTVHITVIDQNDN 3610
D GVP S+ V I V+D+NDN
Sbjct: 687 AVDGGVPPRSAYVGVTINVLDENDN 711
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 343 bits (881), Expect = 2e-93
Identities = 258/802 (32%), Positives = 391/802 (48%), Gaps = 58/802 (7%)
Query: 22 SQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFT-----YRLSE 76
S LL + LL+ PG A R V++V EEQPP TL+G++ GF Y+L
Sbjct: 41 SMLLALLLLLAPSPGHA------TRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEV 94
Query: 77 SHALFAINSSTGALYTTST-IDRESL-------PSDVINL--------VVLSSAPTYPTE 120
++ TG ++TT T IDRE L P D L +V + +P E
Sbjct: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRL-LE 153
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
++ V+D+NDN P F P I + E+++ G + A+D D G NGV SY + G
Sbjct: 154 GQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGV--ASYELQAGP 211
Query: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
EA + + E L+ G LDRE Y L ++V+D G P R + VTV
Sbjct: 212 EAQEL-FGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTV 270
Query: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP----F 296
D NDN P F Y+A + E++ +G SV+QV A D+D+G NA+I Y
Sbjct: 271 LDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLL 330
Query: 297 QMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFR 356
++D TGLITV+ P+D E +V A DRG + RA+ ++ + D+NDN P ++ R
Sbjct: 331 RLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR 390
Query: 357 YFPATSR---YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGG--NEQRHFEVQS 411
+ A++ E+ T VAL+ V+D D N ++ + G + R
Sbjct: 391 GIGLVTHQDGMANISEDVAEETAVALVQVSDRDE-GENAAVTCVVAGDVPFQLRQASETG 449
Query: 412 SKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDH 471
S ++ + LD E++ Y + + D+ G PP SS SL + V D+ND+
Sbjct: 450 SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPP------LSSTNSLKVQVVDVNDN 502
Query: 472 PPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI-VSGNGLGWFHISEHSG 530
PVF+Q V V E PG ++ I+A+D DSG NA L YS+ G F IS +G
Sbjct: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ +S LDRE L + A D+G A ++V +LD ND P F GY+
Sbjct: 563 EIQVKTS--LDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKF-MLSGYNF 619
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
SV+EN P + + M+ DGD G+N V+ S+ E D F + +G + + S DRE
Sbjct: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSV---EQDNGDFVIQNGTGTILSSLSFDRE 676
Query: 651 EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAH--IKENEPGGSYI 708
+Q+ Y+ + A D G PP+S+ + +++LD NDN+P +H + G +
Sbjct: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETV 736
Query: 709 TTVSATDPDLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD 767
+ V+A D D G N + YSI+ G+ FQ+ + SG I+ ++R ++L + +D
Sbjct: 737 SQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSD 796
Query: 768 GGNLQSPNQAIVTITVLDTQDN 789
G A+V + V +T N
Sbjct: 797 RGKPPRYGTALVHLYVNETLAN 818
Score = 290 bits (743), Expect = 2e-77
Identities = 229/764 (29%), Positives = 367/764 (48%), Gaps = 79/764 (10%)
Query: 287 YRLQDEGTPFQMDPETG-LITVREPLDFEARRQ---------------YSLTVQAMDRGV 330
Y+L+ ++D +TG + T +D E R+ S+T + G
Sbjct: 90 YKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSIT-DLVQNGS 148
Query: 331 PSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
P L E I++ D+NDN P F + ++ EN +G++ + +D D+
Sbjct: 149 PRLL---EGQIEVQDINDNTP-----NFASPVITLAIPENTNIGSLFPIPLASDRDA-GP 199
Query: 391 NGNISVQILGGNEQRHF------EVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNY 444
NG S ++ G E + E Q K P L V LDRER SY+LT+ V D
Sbjct: 200 NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLI---VMGNLDRERWDSYDLTIKVQDG- 255
Query: 445 GAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDS 504
G+PP R+S A L + V D ND+ P F + Y LSE +P G V + A D D
Sbjct: 256 GSPP------RASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ 309
Query: 505 GLNANLRYSIVSGNGL--GWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPK 562
G NA + Y+ + + ++GL+T G +DRE S + ++ A+D+G +PK
Sbjct: 310 GANAEIEYTFHQAPEVVRRLLRLDRNTGLITV--QGPVDREDLSTLRFSVLAKDRGTNPK 367
Query: 563 VSYAQLVVTLLDVNDEKPVF--------SQPEGYDVSVVENAPTGTELLMLRATDGDLGD 614
+ AQ+VVT+ D+ND P + +G ++ E+ T + +++ +D D G+
Sbjct: 368 SARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGM-ANISEDVAEETAVALVQVSDRDEGE 426
Query: 615 N--------GTVRFSLQEA-ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
N G V F L++A ET S + L T + LD E+ Y++ ++A D G
Sbjct: 427 NAAVTCVVAGDVPFQLRQASETGSDSKK----KYFLQTTTPLDYEKVKDYTIEIVAVDSG 482
Query: 666 SPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVK 725
+PP SS + V ++D+NDN+PVF EN G I ++A+D D G+N +
Sbjct: 483 NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELV 542
Query: 726 YSISAGDRSR--FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITV 783
YS+ ++ F ++ ++G I + +LDRE++ +Y+L++VA D G+ A V + V
Sbjct: 543 YSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNV 602
Query: 784 LDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQ 843
LD DN P F Y+F V EN+ VG V+ D N ++ G F I
Sbjct: 603 LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQN 662
Query: 844 VTGQLTTANVIDREEQSFY--QLKVVASGGTVTGDTMVNITVK--DLNDNSPHFLQAIES 899
TG + ++ DRE+QS Y QLK V GG V +T+ D NDN+P+ +
Sbjct: 663 GTGTILSSLSFDREQQSTYTFQLKAV-DGGVPPRSAYVGVTINVLDENDNAPYITAPSNT 721
Query: 900 VN--VVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK-QNPKNLFAINEKNGTISLLGPLD 956
+ + + G ++ Q A D D GVN ++YS+ NP LF I +G I+L ++
Sbjct: 722 SHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIE 781
Query: 957 -VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL 999
H G +++ + SD G P + ++ +YV++ N + + L
Sbjct: 782 RRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETL 825
Score = 290 bits (741), Expect = 3e-77
Identities = 224/688 (32%), Positives = 324/688 (47%), Gaps = 53/688 (7%)
Query: 963 QIEILASDM---GVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQ 1019
+ E+ +D+ G P+L I V D+NDN+P F + + E+ + S F
Sbjct: 135 EFEVSITDLVQNGSPRLLEGQI---EVQDINDNTPNFASPVITLAIPENTNIGSLFPIPL 191
Query: 1020 ASDKDSGANGEIAYTIAEG-NTGDAFGIF-------PDGQLYIKSELDRELQDRYVLMVV 1071
ASD+D+G NG +Y + G + FG+ QL + LDRE D Y L +
Sbjct: 192 ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIK 251
Query: 1072 ASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGP 1131
D P +++ + V + D NDN P F +Y E G V +V A D D G
Sbjct: 252 VQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGA 311
Query: 1132 NGEVRYSF----EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
N E+ Y+F E+V+ L +G IT DRE L R F+V+A D+G
Sbjct: 312 NAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLR------FSVLAKDRGT- 364
Query: 1188 QPLKDQATVHVYMKDINDNAPKF--------LKDFYQATISESAANLTQVLRVSASDVDE 1239
P +A V V +KD+NDNAP A ISE A T V V SD DE
Sbjct: 365 NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDE 424
Query: 1240 GNNGLIHYSIIKGNEERQFAIDSTSGQ-------VTLIGKLDYEATPAYSLVIQAVDSGT 1292
G N + ++ G+ Q S +G + LDYE Y++ I AVDSG
Sbjct: 425 GENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGN 483
Query: 1293 IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYY 1352
PL+ST +L + ++D NDN P F +S V EN + GE+++ +TA+D+DSG NA+L Y
Sbjct: 484 PPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVY 543
Query: 1353 SI-TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
S+ G F+ISP TG I + LD E + Y+L + A D+G P T +V+++V
Sbjct: 544 SLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVL 603
Query: 1412 DFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
D NDN P F S++EN+P + V VT D D N Q+ ++ Q F I
Sbjct: 604 DCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD---NGDFVI 660
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
GTI ++ DRE + + +KA D VP R A VTI V D NDN P +
Sbjct: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVP---PRSAYVGVTINVLDENDNAPYITA 717
Query: 1532 QNALA---ADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVA 1587
+ + P +G ++ + A D D G N E+ Y I G+ F + +SG + +
Sbjct: 718 PSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLE 777
Query: 1588 SALVPSQL-IYNLIVSATDLGPERRKST 1614
+ ++ L+V +D G R T
Sbjct: 778 KEIERRHHGLHRLVVKVSDRGKPPRYGT 805
Score = 284 bits (726), Expect = 2e-75
Identities = 222/762 (29%), Positives = 351/762 (46%), Gaps = 58/762 (7%)
Query: 698 IKENEPGGSYITTVSATD--PDLGTNGTVKYSISAGDRSRFQVNAQSG-VISTRMALDRE 754
+ E +P + I +++A PD+G Y + G +V+ ++G + +T ++DRE
Sbjct: 64 VPEEQPPNTLIGSLAADYGFPDVGH----LYKLEVG-APYLRVDGKTGDIFTTETSIDRE 118
Query: 755 -----------EKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVF 803
+ + ++ TD SP I V D DN P F+ + +
Sbjct: 119 GLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIP 178
Query: 804 ENVALGYHVGSVSASTMDLNSN--ISYLITTGDQ-KGMFAIN------QVTGQLTTANVI 854
EN +G AS D N SY + G + + +F + + QL +
Sbjct: 179 ENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNL 238
Query: 855 DREEQSFYQLKV-VASGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHS 911
DRE Y L + V GG+ ++ +TV D NDN+P F + + EN GHS
Sbjct: 239 DRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHS 298
Query: 912 IFQAKAVDPDEGVNGMVLYSLKQNP---KNLFAINEKNGTISLLGPLDVH-AGSYQIEIL 967
+ Q KA D D+G N + Y+ Q P + L ++ G I++ GP+D + + +L
Sbjct: 299 VIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVL 358
Query: 968 ASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVT--------LSESEPVNSRFFKVQ 1019
A D G S+ + V V D+NDN+P + + +SE + VQ
Sbjct: 359 AKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQ 418
Query: 1020 ASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ-------LYIKSELDRELQDRYVLMVVA 1072
SD+D G N + +A G L + LD E Y + +VA
Sbjct: 419 VSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVA 478
Query: 1073 SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPN 1132
D PLS+T ++ V + DVNDN P+F + F E + G + +++A D D G N
Sbjct: 479 VDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
Query: 1133 GEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD 1192
E+ YS E L IS E T + ++ + R + V+A D+G P L+
Sbjct: 539 AELVYSLEPEPAAKGLFTISPE---TGEIQVKTSLDREQRESYELKVVAADRGSPS-LQG 594
Query: 1193 QATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKG 1252
ATV V + D NDN PKF+ Y ++ E+ L+ V V+ D D+G N + S+ +
Sbjct: 595 TATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD 654
Query: 1253 NEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNT 1312
N + F I + +G + D E Y+ ++AVD G P ++ + I++LDENDN
Sbjct: 655 NGD--FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNA 712
Query: 1313 P--SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG 1370
P + P +T + R+GE VS V A D DSG NA+L YSI G N +G F I ++G
Sbjct: 713 PYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSG 772
Query: 1371 SIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
+I L K+++ L++L + D+G+PPR T V ++V +
Sbjct: 773 AITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNE 814
Score = 276 bits (705), Expect = 5e-73
Identities = 213/674 (31%), Positives = 322/674 (47%), Gaps = 53/674 (7%)
Query: 2018 VQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATD 2076
V + DL Q + R + I + D+NDN P F SP +T IPENT I ++ A+D
Sbjct: 138 VSITDLVQNGSPRLL---EGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASD 194
Query: 2077 PDSGPNSYIEYTL-LNPLGNK-FSIGTIDGEVR------LTGELDREEVSNYTLTVVATD 2128
D+GPN Y L P + F + + + + G LDRE +Y LT+ D
Sbjct: 195 RDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQD 254
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P +SS + V VLD NDN P F + Y+ E++EN+ G +IQV A D D+G N +
Sbjct: 255 GGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAE 314
Query: 2189 VRYGIVNGN--TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVS 2246
+ Y + R+D TG ITV P+DRE T +V A DRG+ P++ + V
Sbjct: 315 IEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
Query: 2247 IVLLDINDFVPVFELSPYSV--------NVPENLGTLPRTILQVVARDDDRGSNSKLSYV 2298
+ + D+ND P E+ + N+ E++ L V+ D D G N+ ++ V
Sbjct: 375 VTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS-DRDEGENAAVTCV 433
Query: 2299 LFGGNEDNAFTLSASGELG----------VTQSLDRETKERFVLMITATDSGSPALTGTG 2348
+ G D F L + E G T LD E + + + I A DSG+P L+ T
Sbjct: 434 VAG---DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN 490
Query: 2349 TINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII-----G 2403
++ V V DVNDN P F PE+ G + + ASDAD+ NA +
Sbjct: 491 SLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA 550
Query: 2404 GNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNP 2463
FTI+P TG+I LDRE +++Y L VV +D GSP L + +VLV V D NDN
Sbjct: 551 AKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPS-LQGTATVLVNVLDCNDND 609
Query: 2464 PRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIM 2523
P+F Y + S V VTV D D G N+++ S+ N + F I G I+
Sbjct: 610 PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTIL 668
Query: 2524 AAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQT---FMFP 2577
++ + + T++ +K DGG P++ VT+ +++ D P + A T + P
Sbjct: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
Query: 2578 EN---QPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQK 2634
+ + VS + S + E + Y IA GN FQI +G +++ + ++
Sbjct: 729 QTRLGETVSQVAAEDFDSGVNAE-LIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
Query: 2635 YVVWIEARDGGFPP 2648
+ + ++ D G PP
Sbjct: 788 HRLVVKVSDRGKPP 801
Score = 274 bits (701), Expect = 1e-72
Identities = 216/706 (30%), Positives = 326/706 (46%), Gaps = 55/706 (7%)
Query: 1788 RIDPESGDLIATRR-LDRERRSKYSLLVRAD-----------DGLQSSDMRI---NITVS 1832
R+D ++GD+ T +DRE + + D D +Q+ R+ I V
Sbjct: 100 RVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQ 159
Query: 1833 DVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLN 1892
D+ND+TP F+ PV + IPE+T GSL LA+D D+G NG +Y + E F
Sbjct: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGL 219
Query: 1893 PITG-------VFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVYFNILDVNDNPPI 1943
+ + LD E Y LT++ +DGG + ++ + +LD NDN P
Sbjct: 220 QVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPK 279
Query: 1944 FSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ--FTVDKN-GVL 2000
F SY L EN P+G +V+ D+D G N+++ Y+ + + +D+N G++
Sbjct: 280 FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLI 339
Query: 2001 KVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFL-------- 2052
V +DRE S V D P S + AQV + + D+NDN PT
Sbjct: 340 TVQGPVDREDLSTLRFSVLAKDRGTNPKS---ARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
Query: 2053 -SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE------ 2105
+ I E+ +T V Q +D D G N+ + + + + + G
Sbjct: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
Query: 2106 -VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEIN 2164
++ T LD E+V +YT+ +VA D G P LSS+ + V V+D+NDN P+F Q++ +V
Sbjct: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGI-VNGNTNQEFRIDSVTGAITVAKPLDREKTP 2223
EN G I ++ A+D D G+N ++ Y + F I TG I V LDRE+
Sbjct: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
Query: 2224 TYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV 2283
+Y L V A DRGS T+TV + +LD ND P F LS Y+ +V EN+ L + V
Sbjct: 577 SYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL-SPVGMVT 635
Query: 2284 ARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPA 2343
D D+G N+++ + N D + +G + + S DRE + + + A D G P
Sbjct: 636 VIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPP 694
Query: 2344 LTGTGTINVIVDDVNDNVP--TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA--VI 2399
+ + + V D NDN P T S + G V V A D D+ NA +
Sbjct: 695 RSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIY 754
Query: 2400 RIIGGN--SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSP 2443
I GGN F I +G I ++R + LVV SD G P
Sbjct: 755 SIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
Score = 273 bits (698), Expect = 3e-72
Identities = 215/727 (29%), Positives = 338/727 (46%), Gaps = 56/727 (7%)
Query: 1719 PRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYT 1778
PR ++E+ QDINDN P F + ++ L + EN GS A D D G N + +Y
Sbjct: 149 PRLLEGQIEV--QDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
Query: 1779 IISG--ADDSFRI------DPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRI 1827
+ +G A + F + + + LI LDRER Y L ++ DG ++S +
Sbjct: 207 LQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALL 266
Query: 1828 NITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDE-- 1885
+TV D ND+ PKF RP Y ++ E++ G V + A D D G N EI Y ++ E
Sbjct: 267 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVV 326
Query: 1886 DGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIR--VYFNILDVNDNPPI 1943
+ L+ TG+ + +D E +V A+D G + R V + D+NDN P
Sbjct: 327 RRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPT 386
Query: 1944 FSLNSYS--------TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD 1995
+ ++ E++ + V + V+D D+G N+ +T +A
Sbjct: 387 IEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS 446
Query: 1996 KNG-------VLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNP 2048
+ G L+ LD E Y + + D P S ST + + ++DVNDN
Sbjct: 447 ETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLS---STNSLKVQVVDVNDNA 503
Query: 2049 PTFL-SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--FSIGTIDGE 2105
P F S PEN V+ + A+D DSG N+ + Y+L K F+I GE
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 2106 VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINE 2165
+++ LDRE+ +Y L VVA D+G PSL + V+V VLD NDN+P F + Y + E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 2166 NTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTY 2225
N + + V DGD+G N QV+ + N +F I + TG I + DRE+ TY
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--DFVIQNGTGTILSSLSFDREQQSTY 681
Query: 2226 HLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL---SPYSVNVPENLGTLPRTILQV 2282
++A D G PR+ V+I +LD ND P + + + P+ L T+ QV
Sbjct: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQT--RLGETVSQV 739
Query: 2283 VARDDDRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGS 2341
A D D G N++L Y + GGN F + S SG + + + ++R L++ +D G
Sbjct: 740 AAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGK 799
Query: 2342 PALTGTGTINVIVDDVNDNVPTFASKAYF-TTIPEDAPTGTDVLLVNASDADASK---NA 2397
P GT +++ V++ T A++ T + T D+ + + + SK N
Sbjct: 800 PPRYGTALVHLYVNE------TLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNI 853
Query: 2398 VIRIIGG 2404
+ ++ G
Sbjct: 854 LFGVVAG 860
Score = 260 bits (665), Expect = 2e-68
Identities = 197/663 (29%), Positives = 309/663 (46%), Gaps = 31/663 (4%)
Query: 2657 ITVLDVNDNAPIFKEDPFISEILENLSPRKILTVS-AMDKDSGPNGQLDYEIVNG-NMEN 2714
I V D+NDN P F I EN + + + A D+D+GPNG YE+ G +
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 2715 SFSINHATGEIRS------VRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDEND 2768
F + A + + LDRE+ Y LTIK D GSP +++S + + +LD ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 2769 NAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDA----SLPFTINPS 2823
NAP+F + + A + ENSP+G++V +V +D D G NA Y+ A ++ +
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
Query: 2824 TGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDINDNAPRFSRTSYYL- 2879
TG I + P++RED R V A D G + V + V D+NDNAP L
Sbjct: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
Query: 2880 -------DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQI 2932
+ E + V V +D DEG N V + + A+ +K+
Sbjct: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKK 455
Query: 2933 LKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPV 2992
Q T + ++ + + D G P L S ++ + +VD NDNAP F +S
Sbjct: 456 YFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF 515
Query: 2993 TKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHL-GKFKLDNDTGWISVASSLISDL 3051
+N K G + +TA D D G N+E+ Y + + G F + +TG I V +SL +
Sbjct: 516 PENNKPGEVIAEITA-SDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQ 574
Query: 3052 NQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
+++ + V A D+G+P L ATV + V + N + P+F S + ++ E+ S V V
Sbjct: 575 RESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMV 634
Query: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
+ D D N ++ S+ N G F I + TG + + + D E + + A+DGG
Sbjct: 635 TVIDGDKGENAQVQLSVEQDN--GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGV 692
Query: 3172 VARTGYCSVTVNVIDVNDNSPVFL--SDDYFPTVLENAPSGTTVIHLNATDADSGTNAVI 3229
R+ Y VT+NV+D NDN+P S+ + G TV + A D DSG NA +
Sbjct: 693 PPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAEL 752
Query: 3230 AYTVQSSDS-DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
Y++ + LF I ++G IT + ++ + L VK + R A V++ +
Sbjct: 753 IYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
Query: 3289 KGT 3291
T
Sbjct: 813 NET 815
Score = 260 bits (664), Expect = 3e-68
Identities = 212/669 (31%), Positives = 298/669 (44%), Gaps = 47/669 (7%)
Query: 2124 VVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDE 2183
V TD Q E + V DINDN P FA + + I ENT G+ A+D D
Sbjct: 138 VSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDA 197
Query: 2184 GTNGQVRYGIVNGNTNQEF-------RIDSVTGAITVAKPLDREKTPTYHLTVQATDRGS 2236
G NG Y + G QE + + V LDRE+ +Y LT++ D GS
Sbjct: 198 GPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGS 257
Query: 2237 TPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLS 2296
PR ++ + + +LD ND P FE Y + EN + +++QV A D D+G+N+++
Sbjct: 258 PPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN-SPIGHSVIQVKANDSDQGANAEIE 316
Query: 2297 YVLFGGNEDNAFTLSA---SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVI 2353
Y E L +G + V +DRE + A D G+ + + V
Sbjct: 317 YTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVT 376
Query: 2354 VDDVNDNVPTFASKAY--------FTTIPEDAPTGTDVLLVNASDADASKNAVIR-IIGG 2404
V D+NDN PT + I ED T V LV SD D +NA + ++ G
Sbjct: 377 VKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG 436
Query: 2405 NSQFTINPS--TGQ-------IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
+ F + + TG + T+ LD E +YT+ +V D+G+P PLSS+ S+ V
Sbjct: 437 DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNP-PLSSTNSLKVQ 495
Query: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEK--F 2513
V DVNDN P F P PG + +T +DAD G N+EL YSL + K F
Sbjct: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
Query: 2514 HIDPLRGAIMAAGPLNGASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKAD-FPKVRAK 2570
I P G I L+ ++ + V D GS + TV V ++ D PK
Sbjct: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLS 615
Query: 2571 EQTFMFPENQPVSS---LVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPL 2627
F EN P S +VT I G +GE ++ F I TG + S
Sbjct: 616 GYNFSVMENMPALSPVGMVTVIDGD--KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSF 673
Query: 2628 DFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR-- 2685
D E+ Y ++A DGG PP S+Y + I VLD NDNAP S L L+P+
Sbjct: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL--LTPQTR 731
Query: 2686 ---KILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLT 2742
+ V+A D DSG N +L Y I GN F I +G I + ++R + L
Sbjct: 732 LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
Query: 2743 IKSSDKGSP 2751
+K SD+G P
Sbjct: 792 VKVSDRGKP 800
Score = 259 bits (662), Expect = 5e-68
Identities = 237/745 (31%), Positives = 342/745 (45%), Gaps = 73/745 (9%)
Query: 2276 PRTILQVVARD---DDRGSNSKLS----YVLFGGNEDNAFTLSASGEL-GVTQSLDRETK 2327
P T++ +A D D G KL Y+ G + FT S + G+ + ++
Sbjct: 70 PNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPG 129
Query: 2328 ERFVLM--ITATD---SGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTD 2382
+ +L ++ TD +GSP L G I V D+NDN P FAS IPE+ G+
Sbjct: 130 DPCILEFEVSITDLVQNGSPRLL-EGQIEV--QDINDNTPNFASPVITLAIPENTNIGSL 186
Query: 2383 VLLVNASDADASKNAVI-----------RIIGGNSQFTINPSTGQIITSALLDRETKDNY 2431
+ ASD DA N V + G Q+I LDRE D+Y
Sbjct: 187 FPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSY 246
Query: 2432 TLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVT 2491
L + D GSP P +SS + VTV D NDN P+F+ Y + + G V V
Sbjct: 247 DLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKAN 305
Query: 2492 DADIGPNSELHYSLSGRNS---EKFHIDPLRGAIMAAGPLN--GASEVTFSVHVKDGGSF 2546
D+D G N+E+ Y+ +D G I GP++ S + FSV KD G+
Sbjct: 306 DSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTN 365
Query: 2547 PKTDSTTVTVRFVNKAD-FPKVRAK------EQTFMFPENQPVSS-LVTTITGSSLRGEP 2598
PK+ V V + D P + + Q M ++ V+ + S R E
Sbjct: 366 PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEG 425
Query: 2599 MSYYIASGNLGNT-FQIDQLTGQVSISQ---------PLDFEKIQKYVVWIEARDGGFPP 2648
+ + G+ FQ+ Q + S S+ PLD+EK++ Y + I A D G PP
Sbjct: 426 ENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPP 485
Query: 2649 FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILT-VSAMDKDSGPNGQLDYEI 2707
SS L + V+DVNDNAP+F + EN P +++ ++A D DSG N +L Y +
Sbjct: 486 LSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL 545
Query: 2708 -VNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDE 2766
+ F+I+ TGEI+ LDRE+ Y L + ++D+GSPS + V++N+LD
Sbjct: 546 EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDC 605
Query: 2767 NDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTG 2825
NDN P+F ++ V EN P V VT D D G NA + S+ + F I TG
Sbjct: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTG 665
Query: 2826 DIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRF---SRTSYYL 2879
I+ S +RE Y ++ A D G + VTI V D NDNAP S TS+ L
Sbjct: 666 TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL 725
Query: 2880 DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEY--FRINATTGEI-FNKQILKYQ 2936
P+ T +G V+QV A D D G N ++ Y I + Y F+I + +G I K+I +
Sbjct: 726 LTPQ-TRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRH 784
Query: 2937 NVTGFSNVNINRHSFIVTSSDRGKP 2961
+ H +V SDRGKP
Sbjct: 785 H---------GLHRLVVKVSDRGKP 800
Score = 238 bits (607), Expect = 1e-61
Identities = 198/680 (29%), Positives = 301/680 (44%), Gaps = 53/680 (7%)
Query: 219 LVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADAD 278
+ ++ G P+ L+ + VQDINDN P F S +PE+ +GS A+D D
Sbjct: 140 ITDLVQNGSPR---LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRD 196
Query: 279 EGTNADIRYRLQDEGTPFQM---------DPETGLITVREPLDFEARRQYSLTVQAMDRG 329
G N Y LQ ++ + + + V LD E Y LT++ D G
Sbjct: 197 AGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGG 256
Query: 330 VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPA 389
P A + +LD NDN P F S A + EN+ +G V + D+D
Sbjct: 257 SPPRASSALLRVTVLDTNDNAPK-----FERPSYEAELSENSPIGHSVIQVKANDSDQ-G 310
Query: 390 ANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPG 449
AN I E ++ + N LI V +DRE + + +V D P
Sbjct: 311 ANAEIEYTFHQAPEVVRRLLRLDR--NTGLITVQGPVDREDLSTLRFSVLAKDRGTNP-- 366
Query: 450 AAVQARSSVASLVIFVNDINDHPPVF--------SQQVYRVNLSEEAPPGSYVSGISATD 501
+S+ A +V+ V D+ND+ P + Q N+SE+ + V+ + +D
Sbjct: 367 -----KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSD 421
Query: 502 GDSGLNANLRYSIVSGNGLGWFHISEHSG--------LVTTGSSGGLDRELASQIVLNIS 553
D G NA + +V+G+ + +G L TT LD E + I
Sbjct: 422 RDEGENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIV 477
Query: 554 ARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLG 613
A D G P S L V ++DVND PVF+Q +V+ EN G + + A+D D G
Sbjct: 478 AVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVT-EVAFPENNKPGEVIAEITASDADSG 536
Query: 614 DNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMA 673
N + +SL+ + F + P +G + +SLDRE++ Y L V+A D GSP A
Sbjct: 537 SNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTA 596
Query: 674 RINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR 733
+ V++LD NDN P F Y + EN P S + V+ D D G N V+ S+ D
Sbjct: 597 TVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQ-DN 655
Query: 734 SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVF 793
F + +G I + ++ DRE+++ Y Q+ A DGG VTI VLD DN P
Sbjct: 656 GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYI 715
Query: 794 SQVAYSF--VVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLT 849
+ + + ++ LG V V+A D +N+ + Y I G+ G+F I +G +T
Sbjct: 716 TAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAIT 775
Query: 850 TANVIDREEQSFYQLKVVAS 869
I+R ++L V S
Sbjct: 776 LEKEIERRHHGLHRLVVKVS 795
Score = 236 bits (601), Expect = 6e-61
Identities = 201/691 (29%), Positives = 313/691 (45%), Gaps = 46/691 (6%)
Query: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 2919
I V DINDN P F+ L PE T IGS A+D D G NG Y +++ E
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPE--- 212
Query: 2920 INATTGEIFNKQILKYQN-----VTGFSNVNINR---HSFIVTSSDRGKPSLISETTVTI 2971
E+F Q+ + Q + N++ R + + D G P S + +
Sbjct: 213 ----AQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
Query: 2972 NIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK 3031
++D+NDNAP+F + Y +++N +G +I+V A +D D G N+E+EY + +
Sbjct: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKA-NDSDQGANAEIEYTFHQAPEVVR 327
Query: 3032 --FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 3089
+LD +TG I+V + + +V AKD+G P S++A V +TV + N + P
Sbjct: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
Query: 3090 S------QSHMS--ATIPESHSIGSIVRTVSARDRDAAMN--------GLIKYSISSGNE 3133
+H A I E + + V V DRD N G + + + +E
Sbjct: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
Query: 3134 EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV 3193
G + + L LDYE + + + I A+D G + S+ V V+DVNDN+PV
Sbjct: 448 TG--SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
Query: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGVIT 3251
F EN G + + A+DADSG+NA + Y+++ + LF I P TG I
Sbjct: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ 565
Query: 3252 TQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAA 3311
+ LD E ++SY L V A + ATV + + N+ P+F+ Y F + E
Sbjct: 566 VKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM 625
Query: 3312 PKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSL 3371
P + VG V D D G + +V + F I TG I S DRE++ +
Sbjct: 626 PALSPVGMVTVIDGDKGENAQVQLSV--EQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 3372 KVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTL--NIYSVQISEGVPIGTHVTFVSA 3428
++ A + G + VT+NV LD ND P T N ++ +G V+ V+A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINV--LDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
Query: 3429 FDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTP 3488
D DS + + Y I GN G F I +G IT+ E++R ++ L V D G P
Sbjct: 742 EDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
Query: 3489 SATGSASLLVTLEDINDNGPMLTVSEGEVME 3519
G+A + + + + N +L G ++
Sbjct: 801 PRYGTALVHLYVNETLANRTLLETLLGHSLD 831
Score = 233 bits (593), Expect = 5e-60
Identities = 182/675 (26%), Positives = 306/675 (45%), Gaps = 54/675 (8%)
Query: 2761 INILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM---DASL 2816
I + D NDN P F S + + +PEN+ +G SD D G N ++ Y + +A
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 2817 PFTINPSTGD------IVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDIND 2867
F + + +++ L+RE D Y + + D G S + + V D ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 2868 NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEI 2927
NAP+F R SY + E + IG V QV A D D+G+N ++ Y E R
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVR-------- 327
Query: 2928 FNKQILKYQNVTGFSNV-------NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
++L+ TG V +++ F V + DRG + V + + D NDNA
Sbjct: 328 ---RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNA 384
Query: 2981 PQF--------LKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKF 3032
P ++++V T + + + D+D G N+ V ++ D +
Sbjct: 385 PTIEIRGIGLVTHQDGMANISEDVAEETA-VALVQVSDRDEGENAAVTCVVAGDVPF-QL 442
Query: 3033 KLDNDTG-------WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 3085
+ ++TG ++ + L + +++ I + A D GNPPLSS ++ + V + N +
Sbjct: 443 RQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDN 502
Query: 3086 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS-SGNEEGIFAINSSTG 3144
P F+QS PE++ G ++ ++A D D+ N + YS+ +G+F I+ TG
Sbjct: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
+ + +LD E + +E+ + A D G + G +V VNV+D NDN P F+ Y +V+
Sbjct: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVM 622
Query: 3205 ENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSY 3264
EN P+ + V + D D G NA + +V+ + D FVI TG I + D E + +Y
Sbjct: 623 ENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTY 681
Query: 3265 HLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFV--SKLYYFEISEAAPKGTIVGEVFA 3322
+KA + R ++ V I + N+ P S + ++ G V +V A
Sbjct: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
Query: 3323 SDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKE--ERVSLKVLAKNFGS 3380
D D G + E+ Y I G + FQI +G I + ++R R+ +KV +
Sbjct: 742 EDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPP 801
Query: 3381 IRGADIDEVTVNVTV 3395
G + + VN T+
Sbjct: 802 RYGTALVHLYVNETL 816
Score = 224 bits (570), Expect = 2e-57
Identities = 219/771 (28%), Positives = 334/771 (43%), Gaps = 92/771 (11%)
Query: 1539 PSAVIGSVLTTIMAAD---PDEGANGEIE----YEIINGDTDTFIVDRYSGD---LRVAS 1588
P+ +IGS +AAD PD G ++E Y ++G T S D LR
Sbjct: 70 PNTLIGS-----LAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQ 124
Query: 1589 ALVPSQ-LIYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
+P I VS TDL E I +Q ++ P F P + E IG
Sbjct: 125 NQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIG 184
Query: 1646 TNVISIEAASPR--------------GSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQ 1691
+ + I AS R G EA + + +E+ +L +G
Sbjct: 185 S-LFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGN------ 237
Query: 1692 TAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEE 1751
LDRE+ L ++ + PR A + +T+ D NDN P F + + E
Sbjct: 238 ----LDRERWDSYDLT--IKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSE 291
Query: 1752 NIGDGSKIMQLTAMDADEGANALVTYTIISGAD---DSFRIDPESGDLIATRRLDRERRS 1808
N G ++Q+ A D+D+GANA + YT + R+D +G + +DRE S
Sbjct: 292 NSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLS 351
Query: 1809 KYSLLVRADD---GLQSSDMRINITVSDVNDHTPKFSRPVYSF--------DIPEDTIPG 1857
V A D +S+ ++ +TV D+ND+ P +I ED
Sbjct: 352 TLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEE 411
Query: 1858 SLVAAILATDDDSGVNGEITYIVNED-------------DEDGIFFLNPITGVFNLTRLL 1904
+ VA + +D D G N +T +V D D +FL T L
Sbjct: 412 TAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTP-------L 464
Query: 1905 DYEVQQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGST 1962
DYE + Y + + A D G +T + ++DVNDN P+F+ + + EN G
Sbjct: 465 DYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEV 524
Query: 1963 VLVFNVTDADDGINSQLTYSIASGDSL-GQFTVD-KNGVLKVLKALDRESQSFYNLVVQV 2020
+ +DAD G N++L YS+ + G FT+ + G ++V +LDRE + Y L V
Sbjct: 525 IAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVA 584
Query: 2021 HDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDS 2079
D P+ + T+T V++ LD NDN P F+ + + EN P + V D D
Sbjct: 585 ADRGS-PSLQGTATVLVNV--LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDK 641
Query: 2080 GPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTE 2139
G N+ ++ ++ G+ F I G + + DRE+ S YT + A D G P S+
Sbjct: 642 GENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG 700
Query: 2140 VVVMVLDINDNNPIF---AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNG 2196
V + VLD NDN P + +K+ + T G + QV A D D G N ++ Y I G
Sbjct: 701 VTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGG 759
Query: 2197 NTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
N F+I S +GAIT+ K ++R + L V+ +DRG PR T+ V +
Sbjct: 760 NPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
Score = 213 bits (542), Expect = 4e-54
Identities = 192/745 (25%), Positives = 306/745 (41%), Gaps = 55/745 (7%)
Query: 2899 PDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQ-------ILKYQNVTGFSNVNINRHSF 2951
PD G Y ++ + Y R++ TG+IF + + + QN +
Sbjct: 84 PDVGH----LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVS 139
Query: 2952 IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDK 3011
I G P L+ I + D NDN P F + +N +G+ L + D+
Sbjct: 140 ITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGS-LFPIPLASDR 195
Query: 3012 DFGLNSEVEYFIS---NDNHLGKFKLDNDTG----WISVASSLISDLNQNFFITVTAKDK 3064
D G N Y + L ++ D + V +L + ++ +T+ +D
Sbjct: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDG 255
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLI 3124
G+PP +S A + +TV + N + P+F + A + E+ IG V V A D D N I
Sbjct: 256 GSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEI 315
Query: 3125 KYSISSGNE--EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTV 3182
+Y+ E + ++ +TG++T+ +D E ++ A D G ++ V V
Sbjct: 316 EYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVV 375
Query: 3183 NVIDVNDNSPVF--------LSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQ 3234
V D+NDN+P D + E+ T V + +D D G NA + V
Sbjct: 376 TVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVA 435
Query: 3235 SSDSDLFVIDPNTG-------VITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQ 3287
TG + T LD+E + Y + + A + + S ++ +Q
Sbjct: 436 GDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQ 495
Query: 3288 LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-F 3346
+ N+ P F + E G ++ E+ ASD D G++ E+ Y + KG F
Sbjct: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
Query: 3347 QINKKTGQIYVSGILDREKEERVSLKVLAKNFGS--IRGADIDEVTVNVTVLDAND-PPI 3403
I+ +TG+I V LDRE+ E LKV+A + GS ++G TV V VLD ND P
Sbjct: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT----ATVLVNVLDCNDNDPK 611
Query: 3404 FTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQIT 3463
F L+ Y+ + E +P + V V+ D D + +NG F I TG I
Sbjct: 612 FMLSGYNFSVMENMPALSPVGMVTVIDGDK---GENAQVQLSVEQDNGDFVIQNGTGTIL 668
Query: 3464 VTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT----VSEGEVME 3519
+ DRE Y + AVD G P + + + + D NDN P +T S +
Sbjct: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
Query: 3520 NKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIAD 3579
R G V + + D D N Y + P + S +G ++ +EI+R
Sbjct: 729 QTRLGETVSQVAAEDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
Query: 3580 FYLSVVTKDSGVPQMSSTGTVHITV 3604
L V D G P T VH+ V
Sbjct: 788 HRLVVKVSDRGKPPRYGTALVHLYV 812
Score = 209 bits (532), Expect = 6e-53
Identities = 173/565 (30%), Positives = 270/565 (47%), Gaps = 40/565 (7%)
Query: 3077 ITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNE-EG 3135
I V + N +TP F+ ++ IPE+ +IGS+ A DRDA NG+ Y + +G E +
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
Query: 3136 IFAINSSTGI------LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
+F + + L + LD E +++TI DGG R + V V+D ND
Sbjct: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS---DLFVIDPN 3246
N+P F Y + EN+P G +VI + A D+D G NA I YT + L +D N
Sbjct: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
Query: 3247 TGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVP----RFVSKL 3302
TG+IT QG +D E + +V A + + + A V + +K N+ P R + +
Sbjct: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
Query: 3303 YYFE----ISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI---------N 3349
+ + ISE + T V V SDRD G + V ++ G+ FQ+ +
Sbjct: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVP---FQLRQASETGSDS 452
Query: 3350 KKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNI 3408
KK + + LD EK + +++++A + G+ + + ++ V V+D ND P+FT ++
Sbjct: 453 KKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN--SLKVQVVDVNDNAPVFTQSV 510
Query: 3409 YSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAEL 3468
V E G + ++A D+DS + G F+I+P+TG+I V L
Sbjct: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
Query: 3469 DRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP--MLTVSEGEVMENKRPGTL 3526
DRE Y L V+A D G+PS G+A++LV + D NDN P ML+ VMEN +
Sbjct: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
Query: 3527 VMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVV 3585
V + D D +G LS F + G + ++ DREQ + + +
Sbjct: 631 VGMVTVIDGD----KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLK 686
Query: 3586 TKDSGVPQMSSTGTVHITVIDQNDN 3610
D GVP S+ V I V+D+NDN
Sbjct: 687 AVDGGVPPRSAYVGVTINVLDENDN 711
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
Length = 1955
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 216
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 217 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 276
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 277 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 336
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 337 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 396
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 397 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 454
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 455 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 509
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 510 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 566
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 627 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 683
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 684 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 737
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 738 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 796 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 855
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 856 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 914
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 974
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1034
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1035 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1089
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1090 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1149
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1150 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1209
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1210 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1256
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 195 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 254
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 255 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 314
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 315 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 374
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 375 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 434
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 435 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 492
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 553 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 611
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 612 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 668
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 669 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 728
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 729 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 786
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 906
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 907 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 961
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 962 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1021
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1022 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1077
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1078 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1137
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1138 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1197
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1198 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1226
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 246
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 247 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 306
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 307 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 365
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 366 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 414
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 415 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 466
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 467 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 517
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 518 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 574
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 575 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 634
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 635 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 690
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 691 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 749
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 750 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 807
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 808 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 867
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 868 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 928 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 987
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 988 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1046
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1047 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1102
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1103 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1162
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1163 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1215
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1216 SYFKFQVIATD 1226
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 202 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 261
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 262 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 321
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 322 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 381
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 382 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 441
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 442 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 501
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 502 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 560
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 561 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 613 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 668
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 669 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 727
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 728 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 784
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 785 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 844
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 845 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 902
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 903 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 962
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 963 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1020
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1021 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1075
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1076 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1135
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1136 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1194
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1195 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 381 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 439
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 440 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 492
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 553 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 613 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 664
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 665 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 712
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 770
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 771 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 826
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 827 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 883
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 884 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 943
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 944 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1003
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1004 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1062
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1063 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1121
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1122 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1181
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1182 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1240
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1241 --------SVVNQLDMQVIVSNVPP 1257
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 189 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 428
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 429 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 482
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 483 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 539
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 540 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 598
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 599 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 655
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 656 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 712
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 713 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 768
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 769 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 828
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 829 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 886
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 887 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 946
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 947 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1062 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1119
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1120 RVPSKSNTAKVYIEIQDENNHP 1141
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 191
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 250
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 431 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 489
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 490 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 543
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 544 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 603
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 604 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 656
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 657 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 712
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 769
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 770 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 829
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 830 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 887
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1004
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1005 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1056
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1057 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1114
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1115 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1174
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1175 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1234
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1235 KADVLVSVVNQLDMQVIV 1252
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 190 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 249
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 250 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 309
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 310 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 365
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 366 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 418
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 419 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 478
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 479 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 532
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 589
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 590 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 646
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 647 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 705
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 706 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 764
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 765 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 824 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 881
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 882 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 941
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 942 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1001
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1002 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1060
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1061 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1114
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1115 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1173
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1174 GNYSVMAYRLI 1184
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 200
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 201 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 310
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 431 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 488
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 548
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 549 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 608
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 609 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 665
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 666 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 722
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 723 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 773
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 833
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 834 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 889
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 890 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 923
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 445 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 504
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 505 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 561
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 562 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 613
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 672
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 673 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 730
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 731 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 778
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 779 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 831
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 832 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 887
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 888 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 945
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1062 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1120
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1121 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1180
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1181 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1240
Query: 882 TV 883
+V
Sbjct: 1241 SV 1242
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 556 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 613
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 668
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 669 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 720 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 776
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 777 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 831
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 832 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 884
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 885 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 936
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 937 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 994
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 995 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1053
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1054 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1108
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1109 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1168
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1169 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1228
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1229 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1260
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 638 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 697
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 698 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 753
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 754 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 800
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 860
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 921 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 974
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1030
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1031 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1082
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1083 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1140
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1141 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1199
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1200 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1244
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 225
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 226 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 285
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 286 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 345
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 346 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 523
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 524 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 582
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 583 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 642
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 643 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 697
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 698 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 754
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 755 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 812
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 813 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 848
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 312
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 313 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 372
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 373 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 432
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 433 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 488
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 547
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 548 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 606
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 607 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 660
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 661 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 720 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 773
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
Length = 1932
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 77 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 134
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 135 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 194
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 195 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 254
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 255 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 314
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 315 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 374
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 375 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 432
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 433 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 487
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 488 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 544
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 545 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 604
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 605 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 661
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 662 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 715
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 716 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 773
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 774 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 833
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 834 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 892
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 893 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 952
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 953 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1012
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1013 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1067
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1068 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1127
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1128 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1187
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1188 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1234
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 113 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 172
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 173 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 232
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 233 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 292
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 293 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 352
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 353 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 412
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 413 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 470
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 471 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 530
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 531 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 589
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 590 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 646
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 647 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 706
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 707 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 764
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 765 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 824
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 825 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 884
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 885 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 939
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 940 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 999
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1000 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1055
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1056 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1115
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1116 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1175
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1176 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1204
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 110 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 169
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 170 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 224
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 225 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 284
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 285 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 343
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 344 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 392
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 393 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 444
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 445 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 495
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 496 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 552
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 553 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 612
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 613 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 668
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 669 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 727
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 728 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 785
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 786 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 845
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 846 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 905
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 906 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 965
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 966 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1024
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1025 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1080
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1081 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1140
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1141 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1193
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1194 SYFKFQVIATD 1204
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 180 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 239
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 240 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 299
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 300 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 359
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 360 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 419
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 420 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 479
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 480 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 538
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 539 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 590
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 591 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 646
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 647 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 705
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 706 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 762
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 763 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 822
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 823 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 880
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 881 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 940
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 941 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 998
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 999 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1053
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1054 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1113
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1114 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1172
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1173 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1225
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 359 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 417
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 418 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 470
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 471 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 530
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 531 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 590
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 591 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 642
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 643 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 690
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 691 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 748
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 749 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 804
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 805 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 861
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 862 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 921
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 922 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 981
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 982 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1040
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1041 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1099
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1100 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1159
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1160 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1218
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1219 --------SVVNQLDMQVIVSNVPP 1235
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 108 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 166
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 167 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 226
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 227 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 286
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 287 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 346
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 347 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 406
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 407 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 460
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 461 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 517
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 518 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 576
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 577 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 633
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 634 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 690
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 691 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 746
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 747 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 806
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 807 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 864
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 865 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 924
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 925 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 984 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1039
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1040 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1097
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1098 RVPSKSNTAKVYIEIQDENNHP 1119
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 169
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 170 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 228
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 229 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 288
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 289 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 348
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 349 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 408
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 409 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 467
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 468 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 521
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 522 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 581
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 582 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 634
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 635 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 690
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 691 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 747
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 748 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 807
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 808 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 865
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 866 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 923
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 982
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 983 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1034
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1035 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1092
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1093 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1152
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1153 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1212
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1213 KADVLVSVVNQLDMQVIV 1230
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 108 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 167
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 168 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 227
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 228 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 287
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 288 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 343
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 344 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 396
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 397 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 456
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 457 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 510
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 511 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 567
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 568 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 624
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 625 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 683
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 684 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 742
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 743 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 801
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 802 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 859
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 860 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 919
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 920 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 979
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 980 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1038
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1039 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1092
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1093 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1151
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1152 GNYSVMAYRLI 1162
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 59 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 118
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 119 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 178
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 179 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 230
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 231 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 288
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 289 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 348
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 349 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 408
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 409 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 466
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 467 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 526
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 527 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 586
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 587 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 643
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 644 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 700
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 701 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 751
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 752 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 811
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 812 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 867
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 868 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 901
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 423 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 482
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 483 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 539
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 540 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 591
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 592 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 650
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 651 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 708
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 709 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 756
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 757 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 809
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 810 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 865
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 866 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 923
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 984 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1039
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1040 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1098
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1099 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1158
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1159 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1218
Query: 882 TV 883
+V
Sbjct: 1219 SV 1220
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 534 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 591
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 592 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 646
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 647 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 697
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 698 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 754
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 755 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 809
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 810 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 862
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 863 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 914
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 915 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 972
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 973 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1031
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1032 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1086
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1087 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1146
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1147 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1206
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1207 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1238
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 616 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 675
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 676 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 731
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 732 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 778
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 779 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 838
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 839 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 898
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 899 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 952
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 953 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1008
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1009 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1060
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1061 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1118
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1119 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1177
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1178 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1222
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 87 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 146
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 147 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 203
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 204 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 263
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 264 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 323
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 324 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 383
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 384 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 443
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 444 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 501
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 502 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 560
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 561 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 620
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 621 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 675
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 676 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 732
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 733 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 790
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 791 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 826
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 170
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 171 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 230
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 231 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 290
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 291 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 350
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 351 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 410
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 411 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 466
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 467 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 525
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 526 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 584
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 585 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 638
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 639 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 697
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 698 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 751
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 752 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 800
>gi|218505793 protocadherin 15 isoform CD3-2 precursor [Homo sapiens]
Length = 1677
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 216
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 217 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 276
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 277 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 336
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 337 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 396
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 397 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 454
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 455 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 509
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 510 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 566
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 627 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 683
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 684 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 737
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 738 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 796 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 855
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 856 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 914
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 974
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1034
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1035 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1089
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1090 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1149
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1150 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1209
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1210 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1256
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 195 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 254
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 255 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 314
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 315 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 374
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 375 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 434
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 435 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 492
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 553 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 611
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 612 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 668
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 669 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 728
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 729 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 786
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 906
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 907 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 961
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 962 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1021
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1022 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1077
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1078 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1137
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1138 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1197
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1198 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1226
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 246
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 247 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 306
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 307 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 365
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 366 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 414
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 415 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 466
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 467 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 517
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 518 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 574
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 575 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 634
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 635 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 690
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 691 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 749
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 750 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 807
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 808 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 867
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 868 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 928 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 987
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 988 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1046
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1047 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1102
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1103 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1162
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1163 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1215
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1216 SYFKFQVIATD 1226
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 202 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 261
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 262 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 321
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 322 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 381
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 382 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 441
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 442 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 501
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 502 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 560
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 561 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 613 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 668
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 669 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 727
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 728 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 784
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 785 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 844
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 845 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 902
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 903 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 962
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 963 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1020
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1021 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1075
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1076 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1135
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1136 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1194
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1195 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 381 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 439
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 440 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 492
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 553 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 613 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 664
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 665 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 712
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 770
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 771 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 826
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 827 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 883
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 884 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 943
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 944 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1003
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1004 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1062
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1063 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1121
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1122 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1181
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1182 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1240
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1241 --------SVVNQLDMQVIVSNVPP 1257
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 189 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 428
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 429 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 482
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 483 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 539
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 540 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 598
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 599 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 655
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 656 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 712
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 713 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 768
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 769 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 828
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 829 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 886
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 887 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 946
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 947 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1062 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1119
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1120 RVPSKSNTAKVYIEIQDENNHP 1141
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 191
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 250
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 431 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 489
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 490 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 543
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 544 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 603
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 604 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 656
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 657 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 712
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 769
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 770 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 829
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 830 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 887
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1004
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1005 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1056
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1057 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1114
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1115 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1174
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1175 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1234
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1235 KADVLVSVVNQLDMQVIV 1252
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 190 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 249
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 250 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 309
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 310 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 365
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 366 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 418
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 419 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 478
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 479 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 532
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 589
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 590 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 646
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 647 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 705
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 706 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 764
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 765 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 824 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 881
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 882 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 941
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 942 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1001
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1002 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1060
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1061 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1114
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1115 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1173
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1174 GNYSVMAYRLI 1184
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 200
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 201 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 310
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 431 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 488
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 548
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 549 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 608
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 609 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 665
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 666 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 722
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 723 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 773
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 833
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 834 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 889
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 890 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 923
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 445 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 504
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 505 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 561
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 562 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 613
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 672
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 673 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 730
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 731 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 778
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 779 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 831
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 832 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 887
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 888 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 945
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1062 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1120
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1121 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1180
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1181 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1240
Query: 882 TV 883
+V
Sbjct: 1241 SV 1242
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 556 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 613
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 668
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 669 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 720 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 776
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 777 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 831
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 832 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 884
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 885 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 936
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 937 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 994
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 995 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1053
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1054 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1108
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1109 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1168
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1169 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1228
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1229 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1260
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 638 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 697
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 698 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 753
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 754 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 800
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 860
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 921 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 974
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1030
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1031 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1082
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1083 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1140
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1141 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1199
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1200 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1244
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 225
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 226 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 285
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 286 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 345
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 346 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 523
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 524 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 582
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 583 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 642
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 643 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 697
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 698 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 754
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 755 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 812
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 813 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 848
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 312
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 313 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 372
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 373 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 432
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 433 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 488
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 547
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 548 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 606
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 607 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 660
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 661 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 720 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 773
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
>gi|218505791 protocadherin 15 isoform CD3-1 precursor [Homo sapiens]
Length = 1682
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 104 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 161
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 162 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 221
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 222 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 281
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 282 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 341
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 342 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 401
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 402 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 459
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 460 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 514
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 515 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 571
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 572 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 631
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 632 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 688
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 689 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 742
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 743 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 800
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 801 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 860
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 861 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 919
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 920 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 979
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 980 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1039
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1040 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1094
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1095 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1154
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1155 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1214
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1215 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1261
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 199
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 200 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 259
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 260 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 319
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 320 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 379
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 380 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 439
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 440 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 497
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 498 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 557
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 558 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 616
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 617 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 673
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 674 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 733
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 734 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 791
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 792 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 851
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 852 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 911
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 912 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 966
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 967 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1026
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1027 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1082
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1083 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1142
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1143 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1202
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1203 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1231
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 137 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 251
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 252 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 311
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 312 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 370
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 371 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 419
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 420 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 471
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 472 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 522
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 523 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 579
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 580 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 639
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 640 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 695
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 696 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 754
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 755 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 812
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 813 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 872
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 873 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 932
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 933 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 992
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 993 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1051
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1052 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1107
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1108 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1167
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1168 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1220
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1221 SYFKFQVIATD 1231
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 207 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 266
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 267 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 326
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 327 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 386
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 387 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 446
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 447 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 506
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 507 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 565
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 566 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 617
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 618 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 673
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 674 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 732
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 733 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 789
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 790 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 849
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 850 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 907
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 908 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 967
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 968 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1025
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1026 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1080
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1081 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1140
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1141 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1199
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1200 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1252
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 386 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 444
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 445 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 497
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 498 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 557
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 558 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 617
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 618 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 669
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 670 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 717
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 718 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 775
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 776 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 831
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 832 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 888
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 889 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 948
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 949 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1008
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1009 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1067
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1068 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1126
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1127 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1186
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1187 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1245
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1246 --------SVVNQLDMQVIVSNVPP 1262
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 193
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 194 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 253
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 254 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 313
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 314 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 373
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 374 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 433
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 434 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 487
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 488 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 544
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 545 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 603
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 604 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 660
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 661 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 717
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 718 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 773
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 774 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 833
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 834 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 891
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 892 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 951
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 952 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1011 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1066
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1067 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1124
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1125 RVPSKSNTAKVYIEIQDENNHP 1146
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 196
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 255
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 256 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 315
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 436 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 494
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 495 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 548
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 549 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 608
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 609 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 661
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 662 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 717
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 718 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 774
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 775 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 834
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 835 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 892
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 893 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 950
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1009
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1010 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1061
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1062 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1119
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1120 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1179
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1180 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1239
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1240 KADVLVSVVNQLDMQVIV 1257
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 194
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 195 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 254
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 255 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 314
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 315 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 370
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 371 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 423
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 424 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 483
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 484 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 537
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 538 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 594
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 595 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 651
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 652 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 710
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 711 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 769
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 770 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 828
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 829 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 886
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 887 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 946
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 947 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1006
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1007 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1065
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1066 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1119
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1120 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1178
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1179 GNYSVMAYRLI 1189
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 86 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 145
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 146 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 205
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 206 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 315
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 436 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 493
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 494 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 553
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 554 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 613
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 614 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 670
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 671 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 727
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 728 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 778
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 779 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 838
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 839 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 894
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 895 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 928
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 450 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 509
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 510 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 566
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 567 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 618
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 619 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 677
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 678 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 735
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 736 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 783
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 784 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 836
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 837 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 892
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 893 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 950
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1011 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1066
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1067 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1125
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1126 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1185
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1186 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1245
Query: 882 TV 883
+V
Sbjct: 1246 SV 1247
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 561 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 618
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 619 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 673
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 674 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 724
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 725 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 781
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 782 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 836
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 837 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 889
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 890 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 941
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 942 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 999
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 1000 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1058
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1059 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1113
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1114 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1173
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1174 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1233
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1234 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1265
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 643 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 702
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 703 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 758
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 759 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 805
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 806 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 865
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 866 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 925
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 926 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 979
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 980 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1035
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1036 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1087
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1088 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1145
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1146 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1204
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1205 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1249
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 114 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 173
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 174 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 230
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 231 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 290
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 291 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 350
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 351 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 410
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 411 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 470
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 471 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 528
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 529 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 587
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 588 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 647
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 648 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 702
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 703 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 759
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 760 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 817
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 818 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 853
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 198 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 317
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 318 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 377
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 378 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 437
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 438 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 493
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 494 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 552
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 553 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 611
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 612 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 665
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 666 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 724
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 725 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 778
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 779 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 827
>gi|218505789 protocadherin 15 isoform CD2-2 precursor [Homo sapiens]
Length = 1539
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 216
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 217 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 276
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 277 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 336
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 337 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 396
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 397 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 454
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 455 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 509
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 510 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 566
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 627 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 683
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 684 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 737
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 738 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 796 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 855
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 856 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 914
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 974
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1034
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1035 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1089
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1090 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1149
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1150 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1209
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1210 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1256
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 195 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 254
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 255 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 314
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 315 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 374
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 375 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 434
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 435 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 492
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 553 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 611
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 612 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 668
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 669 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 728
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 729 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 786
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 906
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 907 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 961
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 962 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1021
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1022 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1077
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1078 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1137
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1138 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1197
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1198 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1226
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 246
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 247 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 306
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 307 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 365
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 366 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 414
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 415 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 466
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 467 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 517
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 518 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 574
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 575 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 634
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 635 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 690
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 691 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 749
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 750 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 807
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 808 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 867
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 868 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 928 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 987
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 988 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1046
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1047 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1102
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1103 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1162
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1163 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1215
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1216 SYFKFQVIATD 1226
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 202 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 261
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 262 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 321
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 322 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 381
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 382 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 441
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 442 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 501
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 502 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 560
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 561 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 613 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 668
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 669 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 727
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 728 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 784
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 785 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 844
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 845 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 902
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 903 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 962
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 963 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1020
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1021 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1075
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1076 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1135
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1136 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1194
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1195 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 381 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 439
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 440 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 492
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 553 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 613 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 664
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 665 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 712
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 770
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 771 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 826
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 827 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 883
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 884 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 943
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 944 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1003
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1004 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1062
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1063 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1121
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1122 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1181
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1182 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1240
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1241 --------SVVNQLDMQVIVSNVPP 1257
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 189 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 428
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 429 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 482
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 483 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 539
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 540 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 598
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 599 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 655
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 656 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 712
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 713 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 768
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 769 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 828
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 829 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 886
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 887 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 946
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 947 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1062 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1119
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1120 RVPSKSNTAKVYIEIQDENNHP 1141
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 191
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 250
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 431 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 489
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 490 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 543
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 544 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 603
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 604 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 656
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 657 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 712
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 769
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 770 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 829
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 830 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 887
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1004
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1005 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1056
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1057 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1114
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1115 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1174
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1175 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1234
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1235 KADVLVSVVNQLDMQVIV 1252
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 190 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 249
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 250 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 309
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 310 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 365
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 366 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 418
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 419 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 478
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 479 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 532
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 589
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 590 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 646
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 647 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 705
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 706 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 764
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 765 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 824 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 881
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 882 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 941
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 942 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1001
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1002 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1060
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1061 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1114
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1115 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1173
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1174 GNYSVMAYRLI 1184
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 200
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 201 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 310
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 431 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 488
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 548
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 549 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 608
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 609 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 665
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 666 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 722
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 723 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 773
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 833
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 834 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 889
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 890 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 923
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 445 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 504
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 505 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 561
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 562 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 613
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 672
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 673 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 730
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 731 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 778
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 779 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 831
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 832 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 887
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 888 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 945
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1062 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1120
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1121 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1180
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1181 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1240
Query: 882 TV 883
+V
Sbjct: 1241 SV 1242
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 556 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 613
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 668
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 669 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 720 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 776
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 777 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 831
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 832 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 884
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 885 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 936
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 937 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 994
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 995 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1053
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1054 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1108
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1109 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1168
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1169 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1228
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1229 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1260
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 638 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 697
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 698 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 753
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 754 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 800
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 860
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 921 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 974
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1030
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1031 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1082
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1083 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1140
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1141 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1199
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1200 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1244
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 225
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 226 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 285
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 286 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 345
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 346 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 523
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 524 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 582
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 583 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 642
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 643 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 697
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 698 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 754
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 755 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 812
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 813 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 848
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 312
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 313 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 372
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 373 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 432
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 433 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 488
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 547
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 548 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 606
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 607 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 660
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 661 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 720 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 773
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
Length = 1935
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 77 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 134
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 135 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 194
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 195 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 254
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 255 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 314
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 315 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 374
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 375 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 432
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 433 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 487
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 488 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 544
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 545 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 604
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 605 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 661
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 662 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 715
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 716 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 773
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 774 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 833
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 834 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 892
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 893 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 952
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 953 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1012
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1013 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1067
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1068 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1127
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1128 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1187
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1188 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1234
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 113 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 172
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 173 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 232
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 233 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 292
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 293 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 352
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 353 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 412
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 413 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 470
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 471 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 530
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 531 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 589
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 590 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 646
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 647 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 706
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 707 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 764
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 765 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 824
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 825 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 884
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 885 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 939
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 940 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 999
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1000 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1055
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1056 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1115
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1116 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1175
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1176 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1204
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 110 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 169
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 170 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 224
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 225 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 284
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 285 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 343
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 344 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 392
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 393 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 444
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 445 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 495
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 496 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 552
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 553 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 612
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 613 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 668
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 669 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 727
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 728 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 785
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 786 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 845
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 846 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 905
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 906 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 965
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 966 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1024
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1025 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1080
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1081 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1140
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1141 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1193
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1194 SYFKFQVIATD 1204
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 180 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 239
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 240 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 299
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 300 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 359
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 360 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 419
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 420 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 479
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 480 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 538
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 539 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 590
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 591 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 646
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 647 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 705
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 706 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 762
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 763 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 822
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 823 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 880
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 881 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 940
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 941 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 998
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 999 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1053
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1054 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1113
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1114 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1172
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1173 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1225
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 359 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 417
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 418 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 470
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 471 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 530
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 531 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 590
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 591 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 642
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 643 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 690
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 691 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 748
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 749 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 804
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 805 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 861
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 862 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 921
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 922 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 981
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 982 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1040
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1041 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1099
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1100 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1159
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1160 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1218
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1219 --------SVVNQLDMQVIVSNVPP 1235
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 108 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 166
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 167 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 226
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 227 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 286
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 287 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 346
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 347 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 406
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 407 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 460
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 461 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 517
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 518 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 576
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 577 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 633
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 634 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 690
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 691 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 746
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 747 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 806
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 807 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 864
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 865 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 924
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 925 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 984 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1039
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1040 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1097
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1098 RVPSKSNTAKVYIEIQDENNHP 1119
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 169
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 170 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 228
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 229 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 288
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 289 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 348
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 349 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 408
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 409 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 467
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 468 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 521
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 522 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 581
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 582 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 634
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 635 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 690
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 691 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 747
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 748 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 807
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 808 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 865
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 866 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 923
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 982
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 983 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1034
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1035 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1092
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1093 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1152
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1153 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1212
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1213 KADVLVSVVNQLDMQVIV 1230
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 108 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 167
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 168 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 227
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 228 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 287
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 288 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 343
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 344 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 396
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 397 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 456
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 457 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 510
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 511 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 567
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 568 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 624
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 625 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 683
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 684 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 742
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 743 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 801
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 802 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 859
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 860 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 919
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 920 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 979
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 980 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1038
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1039 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1092
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1093 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1151
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1152 GNYSVMAYRLI 1162
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 59 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 118
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 119 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 178
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 179 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 230
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 231 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 288
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 289 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 348
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 349 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 408
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 409 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 466
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 467 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 526
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 527 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 586
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 587 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 643
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 644 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 700
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 701 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 751
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 752 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 811
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 812 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 867
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 868 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 901
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 423 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 482
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 483 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 539
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 540 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 591
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 592 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 650
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 651 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 708
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 709 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 756
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 757 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 809
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 810 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 865
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 866 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 923
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 924 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 983
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 984 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1039
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1040 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1098
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1099 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1158
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1159 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1218
Query: 882 TV 883
+V
Sbjct: 1219 SV 1220
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 534 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 591
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 592 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 646
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 647 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 697
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 698 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 754
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 755 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 809
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 810 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 862
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 863 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 914
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 915 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 972
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 973 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1031
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1032 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1086
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1087 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1146
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1147 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1206
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1207 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1238
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 616 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 675
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 676 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 731
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 732 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 778
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 779 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 838
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 839 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 898
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 899 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 952
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 953 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1008
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1009 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1060
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1061 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1118
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1119 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1177
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1178 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1222
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 87 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 146
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 147 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 203
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 204 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 263
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 264 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 323
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 324 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 383
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 384 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 443
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 444 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 501
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 502 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 560
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 561 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 620
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 621 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 675
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 676 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 732
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 733 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 790
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 791 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 826
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 111 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 170
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 171 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 230
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 231 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 290
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 291 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 350
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 351 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 410
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 411 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 466
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 467 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 525
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 526 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 584
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 585 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 638
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 639 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 697
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 698 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 751
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 752 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 800
>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens]
Length = 1952
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 216
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 217 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 276
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 277 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 336
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 337 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 396
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 397 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 454
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 455 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 509
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 510 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 566
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 627 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 683
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 684 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 737
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 738 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 796 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 855
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 856 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 914
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 974
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1034
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1035 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1089
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1090 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1149
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1150 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1209
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1210 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1256
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 195 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 254
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 255 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 314
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 315 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 374
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 375 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 434
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 435 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 492
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 553 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 611
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 612 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 668
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 669 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 728
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 729 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 786
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 906
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 907 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 961
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 962 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1021
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1022 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1077
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1078 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1137
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1138 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1197
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1198 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1226
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 246
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 247 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 306
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 307 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 365
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 366 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 414
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 415 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 466
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 467 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 517
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 518 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 574
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 575 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 634
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 635 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 690
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 691 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 749
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 750 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 807
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 808 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 867
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 868 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 928 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 987
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 988 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1046
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1047 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1102
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1103 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1162
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1163 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1215
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1216 SYFKFQVIATD 1226
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 202 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 261
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 262 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 321
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 322 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 381
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 382 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 441
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 442 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 501
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 502 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 560
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 561 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 613 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 668
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 669 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 727
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 728 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 784
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 785 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 844
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 845 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 902
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 903 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 962
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 963 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1020
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1021 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1075
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1076 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1135
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1136 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1194
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1195 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 381 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 439
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 440 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 492
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 553 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 613 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 664
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 665 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 712
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 770
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 771 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 826
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 827 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 883
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 884 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 943
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 944 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1003
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1004 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1062
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1063 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1121
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1122 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1181
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1182 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1240
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1241 --------SVVNQLDMQVIVSNVPP 1257
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 189 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 428
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 429 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 482
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 483 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 539
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 540 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 598
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 599 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 655
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 656 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 712
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 713 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 768
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 769 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 828
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 829 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 886
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 887 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 946
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 947 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1062 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1119
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1120 RVPSKSNTAKVYIEIQDENNHP 1141
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 191
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 250
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 431 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 489
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 490 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 543
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 544 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 603
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 604 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 656
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 657 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 712
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 769
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 770 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 829
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 830 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 887
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1004
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1005 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1056
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1057 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1114
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1115 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1174
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1175 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1234
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1235 KADVLVSVVNQLDMQVIV 1252
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 190 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 249
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 250 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 309
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 310 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 365
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 366 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 418
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 419 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 478
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 479 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 532
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 589
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 590 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 646
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 647 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 705
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 706 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 764
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 765 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 824 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 881
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 882 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 941
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 942 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1001
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1002 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1060
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1061 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1114
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1115 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1173
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1174 GNYSVMAYRLI 1184
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 200
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 201 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 310
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 431 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 488
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 548
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 549 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 608
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 609 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 665
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 666 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 722
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 723 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 773
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 833
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 834 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 889
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 890 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 923
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 445 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 504
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 505 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 561
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 562 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 613
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 672
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 673 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 730
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 731 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 778
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 779 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 831
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 832 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 887
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 888 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 945
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1062 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1120
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1121 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1180
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1181 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1240
Query: 882 TV 883
+V
Sbjct: 1241 SV 1242
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 556 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 613
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 668
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 669 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 720 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 776
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 777 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 831
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 832 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 884
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 885 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 936
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 937 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 994
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 995 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1053
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1054 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1108
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1109 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1168
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1169 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1228
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1229 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1260
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 638 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 697
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 698 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 753
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 754 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 800
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 860
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 921 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 974
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1030
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1031 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1082
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1083 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1140
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1141 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1199
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1200 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1244
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 225
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 226 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 285
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 286 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 345
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 346 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 523
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 524 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 582
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 583 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 642
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 643 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 697
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 698 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 754
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 755 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 812
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 813 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 848
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 312
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 313 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 372
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 373 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 432
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 433 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 488
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 547
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 548 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 606
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 607 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 660
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 661 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 720 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 773
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
>gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapiens]
Length = 1957
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 216
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 217 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 276
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 277 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 336
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 337 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 396
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 397 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 454
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 455 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 509
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 510 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 566
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 627 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 683
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 684 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 737
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 738 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 795
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 796 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 855
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 856 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 914
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 915 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 974
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1034
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1035 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1089
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1090 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1149
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1150 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1209
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1210 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1256
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 195 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 254
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 255 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 314
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 315 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 374
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 375 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 434
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 435 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 492
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 553 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 611
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 612 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 668
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 669 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 728
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 729 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 786
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 787 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 846
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 847 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 906
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 907 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 961
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 962 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1021
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1022 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1077
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1078 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1137
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1138 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1197
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1198 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1226
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 246
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 247 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 306
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 307 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 365
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 366 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 414
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 415 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 466
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 467 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 517
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 518 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 574
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 575 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 634
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 635 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 690
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 691 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 749
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 750 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 807
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 808 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 867
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 868 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 927
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 928 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 987
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 988 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1046
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1047 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1102
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1103 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1162
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1163 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1215
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1216 SYFKFQVIATD 1226
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 202 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 261
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 262 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 321
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 322 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 381
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 382 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 441
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 442 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 501
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 502 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 560
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 561 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 613 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 668
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 669 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 727
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 728 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 784
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 785 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 844
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 845 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 902
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 903 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 962
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 963 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1020
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1021 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1075
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1076 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1135
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1136 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1194
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1195 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1247
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 381 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 439
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 440 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 492
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 493 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 552
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 553 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 612
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 613 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 664
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 665 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 712
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 713 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 770
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 771 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 826
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 827 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 883
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 884 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 943
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 944 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1003
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1004 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1062
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1063 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1121
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1122 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1181
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1182 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1240
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1241 --------SVVNQLDMQVIVSNVPP 1257
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 189 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 248
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 249 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 308
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 309 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 368
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 369 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 428
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 429 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 482
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 483 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 539
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 540 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 598
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 599 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 655
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 656 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 712
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 713 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 768
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 769 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 828
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 829 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 886
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 887 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 946
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 947 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1062 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1119
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1120 RVPSKSNTAKVYIEIQDENNHP 1141
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 191
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 192 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 250
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 431 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 489
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 490 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 543
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 544 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 603
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 604 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 656
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 657 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 712
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 713 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 769
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 770 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 829
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 830 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 887
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 888 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 945
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1004
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1005 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1056
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1057 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1114
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1115 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1174
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1175 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1234
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1235 KADVLVSVVNQLDMQVIV 1252
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 190 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 249
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 250 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 309
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 310 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 365
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 366 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 418
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 419 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 478
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 479 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 532
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 533 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 589
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 590 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 646
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 647 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 705
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 706 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 764
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 765 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 824 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 881
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 882 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 941
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 942 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1001
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1002 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1060
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1061 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1114
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1115 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1173
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1174 GNYSVMAYRLI 1184
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 200
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 201 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 310
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 431 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 488
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 548
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 549 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 608
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 609 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 665
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 666 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 722
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 723 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 773
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 833
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 834 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 889
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 890 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 923
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 445 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 504
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 505 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 561
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 562 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 613
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 672
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 673 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 730
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 731 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 778
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 779 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 831
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 832 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 887
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 888 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 945
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 946 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1005
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1006 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1061
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1062 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1120
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1121 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1180
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1181 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1240
Query: 882 TV 883
+V
Sbjct: 1241 SV 1242
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 556 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 613
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 614 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 668
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 669 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 720 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 776
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 777 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 831
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 832 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 884
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 885 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 936
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 937 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 994
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 995 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1053
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1054 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1108
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1109 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1168
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1169 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1228
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1229 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1260
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 638 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 697
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 698 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 753
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 754 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 800
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 801 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 860
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 861 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 920
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 921 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 974
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 975 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1030
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1031 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1082
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1083 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1140
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1141 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1199
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1200 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1244
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 225
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 226 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 285
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 286 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 345
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 346 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 405
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 406 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 465
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 466 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 523
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 524 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 582
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 583 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 642
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 643 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 697
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 698 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 754
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 755 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 812
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 813 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 848
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 252
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 253 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 312
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 313 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 372
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 373 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 432
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 433 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 488
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 489 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 547
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 548 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 606
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 607 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 660
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 661 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 719
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 720 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 773
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 774 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 822
>gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapiens]
Length = 1962
Score = 343 bits (879), Expect = 3e-93
Identities = 319/1192 (26%), Positives = 533/1192 (44%), Gaps = 135/1192 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 104 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 161
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 162 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 221
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 222 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 281
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 282 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 341
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 342 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 401
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYSIASGDSLGQFTV 1994
+ SY ++E+ PVG+T+ N+T D +D + +L + D FTV
Sbjct: 402 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFL--NDYTSVFTV 459
Query: 1995 DKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
+ G+ L +L+ +DRE Q Y + D Q + V+I ++D NDN PTF
Sbjct: 460 TQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDANDNTPTF 514
Query: 2052 LSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVR 2107
P+++Y + P D+V+ + A D D G N I Y +L F I G +
Sbjct: 515 --PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLIT 571
Query: 2108 LTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALYKVEIN 2164
+ ++ Y LTV A D P+ ++ V + + NN P F Q +Y +EI+
Sbjct: 572 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 631
Query: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPT 2224
E G ++ + A D + + Y I NG+ + F + TG +T+ K LDRE T
Sbjct: 632 EAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDR 688
Query: 2225 YHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT----IL 2280
Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL + +
Sbjct: 689 YILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEANAFVG 742
Query: 2281 QVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSG 2340
QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++ ATD
Sbjct: 743 QVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGA 800
Query: 2341 SPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIR 2400
T T+ + V D++DN P F + Y + E+ P GT +L + A D D N R
Sbjct: 801 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYR 860
Query: 2401 IIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSSTSVLV 2454
I + F ++P TG++ LD E + + T +V D P +T V V
Sbjct: 861 IRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIAT-VTV 919
Query: 2455 TVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSGRN--- 2509
V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 920 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 979
Query: 2510 -SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKADFPK 2566
+ F ++ G ++ LN F + V D G + S TV + ++ + P+
Sbjct: 980 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 1039
Query: 2567 VRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQV 2621
+E PVS L T + ++ + + Y I SGN +TF I+ +TG +
Sbjct: 1040 FTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVI 1094
Query: 2622 SISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 2674
++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F++ +
Sbjct: 1095 YVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFY 1154
Query: 2675 ISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEIRSVRP 2730
I + E+ +L V A DKD+G + Y ++ + + F + TG I++
Sbjct: 1155 IGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAML 1214
Query: 2731 LDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
+ S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1215 FHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1261
Score = 331 bits (849), Expect = 1e-89
Identities = 298/1109 (26%), Positives = 500/1109 (45%), Gaps = 88/1109 (7%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 199
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 200 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 259
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 260 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 319
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 320 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 379
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLG 719
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+
Sbjct: 380 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 439
Query: 720 TNGTVKYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQ 776
+ + D + Q+G+ ++ +DREE+ Y I A DG +Q
Sbjct: 440 DTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEP 497
Query: 777 AIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGD 834
IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G
Sbjct: 498 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 557
Query: 835 QKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------ND 888
Q G F IN+ TG +T A ++ Y L V A+ + +I + N
Sbjct: 558 Q-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQ 616
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNG 947
+ P F Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G
Sbjct: 617 SPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTG 673
Query: 948 TISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSE 1007
++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 674 ILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVV 733
Query: 1008 SEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYV 1067
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y
Sbjct: 734 EEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYE 791
Query: 1068 LMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDK 1127
L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D
Sbjct: 792 LVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDV 851
Query: 1128 DFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
D G N R V+ F LH +GE++ D E+ + + F +P
Sbjct: 852 DLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 911
Query: 1188 QPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
+ ATV V +KD+ND P F K Y+ ++ A T + V A D D GL
Sbjct: 912 PGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPAS 966
Query: 1248 SIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCT 1300
+ ++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T
Sbjct: 967 RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSAT 1026
Query: 1301 LNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNH 1360
+ I +L + + V E G +V ++A + N + YSI N
Sbjct: 1027 VKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEE 1082
Query: 1361 GTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDF 1413
TF I+ TG I++ LD+ET++ Y L + A + P +S+T V I ++D
Sbjct: 1083 DTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDE 1142
Query: 1414 NDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTI 1471
N++PP F + E+ + TSV+ V A D D ++Y II + G F +
Sbjct: 1143 NNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVV 1202
Query: 1472 DEVKGTIYTNAEIDREFANLFELTVKAND 1500
+ G I T + F+ V A D
Sbjct: 1203 ETYTGLIKTAMLFHNMRRSYFKFQVIATD 1231
Score = 298 bits (764), Expect = 7e-80
Identities = 309/1151 (26%), Positives = 507/1151 (44%), Gaps = 143/1151 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 137 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 251
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 252 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 311
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 312 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 370
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTV 382
+A D G P L A I++LD N+ P YF S + E+A VG +
Sbjct: 371 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATI----- 419
Query: 383 TDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL-------------------IKVA 423
S + N ++I+ ++ +++ +K P L L + +
Sbjct: 420 ----SDSLNLTSPLRIVALDK----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLL 471
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+DRE +Y +++ D S + I V D ND+ P F + Y V
Sbjct: 472 QPVDREEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVY 522
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ + PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++
Sbjct: 523 VYTDMRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMI 579
Query: 544 LASQIVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTE 601
+ L + A D + S + + +L N++ P Y + + E G
Sbjct: 580 VGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAV 639
Query: 602 LLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLA 661
LL L+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A
Sbjct: 640 LLNLQATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITA 695
Query: 662 TDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTN 721
+D G P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G N
Sbjct: 696 SD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN 754
Query: 722 GTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
G V YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I
Sbjct: 755 GQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAI 812
Query: 782 TVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAI 841
VLD DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA+
Sbjct: 813 KVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFAL 872
Query: 842 NQVTGQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFL 894
+ TG+L+ + D+E + ++ GT+ G V + VKD+ND P F
Sbjct: 873 HPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFS 932
Query: 895 QAIESVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGT 948
+ I V + G I A+ DP V Y + P ++F + E +G
Sbjct: 933 KRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGR 992
Query: 949 ISLLGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLS 1006
+ L+ + +++ ++A D G P +SSS + + V + P F Q Y +S
Sbjct: 993 VITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVS 1051
Query: 1007 ESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDR 1065
E + + A + N I Y+I GN D FGI G +Y+ LD E +
Sbjct: 1052 ELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTS 1107
Query: 1066 YVLM-------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSF 1118
YVL VV ++ V S T V + ++D N++ P+F Y E+ R +
Sbjct: 1108 YVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTS 1167
Query: 1119 VGKVSAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGT 1172
V +V A DKD G + Y ++ P F + +G I F MRR
Sbjct: 1168 VLRVKATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR--- 1220
Query: 1173 AVFSFTVIATD 1183
+ F F VIATD
Sbjct: 1221 SYFKFQVIATD 1231
Score = 288 bits (737), Expect = 9e-77
Identities = 286/1073 (26%), Positives = 476/1073 (44%), Gaps = 100/1073 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 207 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 266
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 267 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 326
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 327 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 386
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI
Sbjct: 387 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 446
Query: 2810 SIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSAHDSGW-TVSTDVTIFVTD 2864
+ D + FT+ + T + + +P++RE+ Y ++A D + V I V D
Sbjct: 447 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMD 506
Query: 2865 INDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQSEYFRINA 2922
NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q ++ IN
Sbjct: 507 ANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFI-INK 565
Query: 2923 TTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV---DSNDN 2979
TTG I G + ++ V ++D P+ + T+ I +N +
Sbjct: 566 TTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 617
Query: 2980 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTG 3039
P+F + Y +++ ++VG L+ + A D + + Y I N + F L TG
Sbjct: 618 PPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSETTG 673
Query: 3040 WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIP 3099
+++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 674 ILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 732
Query: 3100 ESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQK 3159
+ V V A D DA +NG + YS+ GN +F I S+ I T K L+ E+
Sbjct: 733 VEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-LNREVRDY 789
Query: 3160 HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT 3219
+E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT++ + A
Sbjct: 790 YELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAK 849
Query: 3220 DADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLTVKAFNVP 3274
D D G N ++Y ++S + F + P TG ++ LD+E + S V+AF++
Sbjct: 850 DVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIY 907
Query: 3275 DEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLG--TDGE 3332
ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 908 GTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASR 967
Query: 3333 VHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEV 3389
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 968 VRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGEPVMSSSA 1025
Query: 3390 TVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGN 3448
TV + VL + P FT Y +SE GT V +SA + Y I SGN
Sbjct: 1026 TVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIVYSIVSGN 1080
Query: 3449 ENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSASLLVTLE 3501
E F IN TG I V LD ET Y +L V+ + PS + +A + + ++
Sbjct: 1081 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1140
Query: 3502 DINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--STGPATSY 3557
D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1141 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPPIKEGKEG 1199
Query: 3558 FSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1200 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1252
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 386 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 444
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 445 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 497
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 498 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 557
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 558 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 617
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 618 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 669
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 670 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 717
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 718 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 775
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 776 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 831
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 832 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 888
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 889 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 948
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 949 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 1008
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 1009 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1067
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1068 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1126
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1127 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1186
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1187 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1245
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1246 --------SVVNQLDMQVIVSNVPP 1262
Score = 268 bits (686), Expect = 8e-71
Identities = 283/1042 (27%), Positives = 475/1042 (45%), Gaps = 112/1042 (10%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 193
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 194 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 253
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 254 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 313
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 314 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 373
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 374 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 433
Query: 2897 TDPD--EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVT 2954
D D + + ++ F+ + F + T + + Q V ++F +T
Sbjct: 434 LDKDIEDTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSIT 487
Query: 2955 SSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFG 3014
+ D + S V I ++D+NDN P F + Y V +++ G +I++TA+D D G
Sbjct: 488 AFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEG 544
Query: 3015 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQ 3072
N E+ Y I G F ++ TG I++A + + + + +TV A D P +S
Sbjct: 545 SNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSI 603
Query: 3073 ATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSG 3131
TV+I V N +P F Q S I E+ +G+++ + A DR+ I Y+I +G
Sbjct: 604 CTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENG 660
Query: 3132 NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVND 3189
+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN++ DVND
Sbjct: 661 DPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVND 717
Query: 3190 NSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNT 3247
N+PVF D Y P L + V + ATD D+G N + Y++ + ++LF I N
Sbjct: 718 NAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN- 773
Query: 3248 GVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEI 3307
G I T L+ E + Y L V A + R S T+ I++ ++ P F + Y +
Sbjct: 774 GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLV 833
Query: 3308 SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK-- 3365
E P GT + ++ A D DLG + V Y I K F ++ TG++ + LD E
Sbjct: 834 EENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFP 891
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVT 3424
++ S+ L + F TV V V D ND PP+F+ IY ++ GT +T
Sbjct: 892 DQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPIT 951
Query: 3425 FVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLS 3479
V A D+D +P+ SR Y + F + +G++ L+ E I+ L
Sbjct: 952 TVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 3480 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPD 3536
V+A D G P + SA++ + + + P T E V E GT+V + +
Sbjct: 1011 VVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA--- 1066
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDS 3589
NQ Y ++S ++ + GV+ +D E + L VV +
Sbjct: 1067 -AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANL 1124
Query: 3590 GVPQMSSTGTVHITVIDQNDNP 3611
VP S+T V+I + D+N++P
Sbjct: 1125 RVPSKSNTAKVYIEIQDENNHP 1146
Score = 260 bits (665), Expect = 2e-68
Identities = 303/1158 (26%), Positives = 498/1158 (43%), Gaps = 135/1158 (11%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 196
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 255
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 256 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 315
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHD 1446
P + + I + D N+ P F I+E+ P+G TS + + A D
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVP 1504
D + + + FT+ + T Y +DRE + ++ A D
Sbjct: 436 KDIEDTKDPELHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE 494
Query: 1505 IETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGE 1562
E V I V D NDN P F IS + SV+ + A D DEG+NGE
Sbjct: 495 SEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGE 548
Query: 1563 IEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIIL 1621
I YEI+ G FI+++ +G + +A + + Y L V A D P + + T+ +
Sbjct: 549 ITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYI 608
Query: 1622 QGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKT 1676
+ L P F Q Y + E +G +++++A G ++ E
Sbjct: 609 EVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGD 661
Query: 1677 VGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDIND 1735
R+F + TGI+ LDRE L+ I S P T A V I + D+ND
Sbjct: 662 PQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVND 717
Query: 1736 NPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESG 1794
N PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G
Sbjct: 718 NAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNG 774
Query: 1795 DLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
+ +L+RE R Y L+V A DG + S + + I V D++D++P F+ Y+ +
Sbjct: 775 SIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVE 834
Query: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV--- 1908
E+ G+ + I A D D G N ++Y + + F L+P TG +L R LDYE
Sbjct: 835 ENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 892
Query: 1909 -QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTV 1963
+ V A D G T+ V + D+ND PP+FS Y + + G+ +
Sbjct: 893 QEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPI 950
Query: 1964 LVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNL 2016
DAD G+ S++ Y + S+ + D V+ + L+ E + + L
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKL 1009
Query: 2017 VVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATD 2076
VV D + S S+A V I++L + P F + Y P P+ + K
Sbjct: 1010 VVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVG 1061
Query: 2077 PDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTV 2124
S N I Y++++ GN+ F I I G + + G LD E ++Y +L V
Sbjct: 1062 VISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEV 1119
Query: 2125 VATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEG 2184
V + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G
Sbjct: 1120 VLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTG 1179
Query: 2185 TNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTP 2238
+ Y ++ + F +++ TG I A + + V ATD +G +
Sbjct: 1180 NYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSG 1239
Query: 2239 RTDTSTVSIVLLDINDFV 2256
+ D + LD+ V
Sbjct: 1240 KADVLVSVVNQLDMQVIV 1257
Score = 250 bits (639), Expect = 2e-65
Identities = 288/1091 (26%), Positives = 459/1091 (42%), Gaps = 109/1091 (9%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 194
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 195 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 254
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 255 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 314
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 315 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 370
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG-- 496
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S
Sbjct: 371 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 423
Query: 497 -------ISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIV 549
I A D D + + + F +++ +DRE
Sbjct: 424 NLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYT 483
Query: 550 LNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLR 606
+I+A D Q P + + + ++D ND P F PE YDV V + G ++ L
Sbjct: 484 FSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVIQLT 537
Query: 607 ATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
A D D G NG + + L A+ D F ++ +G ++ ++ Y+L V A D
Sbjct: 538 AVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 594
Query: 666 SPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATDPDLGTNG 722
P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD +
Sbjct: 595 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GD 651
Query: 723 TVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI 781
++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G + A V I
Sbjct: 652 SITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 710
Query: 782 TVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFA 840
V D DN PVF + + V E A + VG V A+ D N + G+ +F
Sbjct: 711 VVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFR 769
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNSPHFLQAI 897
I G + TA ++RE + +Y+L VVA+ G V + I V D++DNSP F +
Sbjct: 770 ITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 828
Query: 898 ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLD 956
+V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +SLL LD
Sbjct: 829 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 886
Query: 957 VHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPV 1011
A S + A D+ +TV V D+ND PVF + Y+ ++
Sbjct: 887 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 946
Query: 1012 NSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDR 1065
+ V A D D + Y + + IF G++ + L+ E
Sbjct: 947 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 1006
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSA 1124
+ L+VVA D +S++ V +++ + P F Y E G+ VG +SA
Sbjct: 1007 FKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA 1065
Query: 1125 VDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGTAVFSFTV 1179
N + YS + F ++ I+G I D R S + R S V
Sbjct: 1066 A----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--VQADSLEV 1119
Query: 1180 IATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDE 1239
+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV A+D D
Sbjct: 1120 VLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDT 1178
Query: 1240 GNNGLIHYSII 1250
GN ++ Y +I
Sbjct: 1179 GNYSVMAYRLI 1189
Score = 234 bits (598), Expect = 1e-60
Identities = 238/874 (27%), Positives = 378/874 (43%), Gaps = 99/874 (11%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 86 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 145
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 146 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 205
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 206 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 315
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARD 3115
PL + A +HI + +EN +P F+ I ES +G+ + + A D
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 3116 RDAAMNGLIKYSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVA 3173
+D + + + +F + + T LTL + +D E Q + +I+A DG V
Sbjct: 436 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQ 493
Query: 3174 RTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTV 3233
+ V + V+D NDN+P F Y V + G +VI L A DAD G+N I Y +
Sbjct: 494 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 553
Query: 3234 QSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKG 3290
F+I+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L
Sbjct: 554 LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPP 613
Query: 3291 TNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINK 3350
N+ PRF +Y EISEA G ++ + A+DR+ + Y I ++ F +++
Sbjct: 614 NNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSE 670
Query: 3351 KTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFT 3405
TG + + LDRE +R L + A + R TVN+ V D ND P
Sbjct: 671 TTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLP 727
Query: 3406 LNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITV 3464
N+ V+ +G V A D D+ I +S GN N F I G I
Sbjct: 728 RNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYT 778
Query: 3465 TAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKR 3522
+L+RE Y L V+A D + +L + + DI+DN P+ T S V+ EN
Sbjct: 779 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLP 838
Query: 3523 PGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFY 3581
GT ++ +++ D DL N Y + + +F+L G LS R +D E D
Sbjct: 839 AGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQE 894
Query: 3582 LSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
S+ D TV + V D ND P
Sbjct: 895 ASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 928
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 450 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 509
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 510 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 566
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 567 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 618
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 619 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 677
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 678 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 735
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 736 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 783
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 784 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 836
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 837 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 892
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 893 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 950
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 951 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 1010
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 1011 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1066
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1067 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1125
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1126 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1185
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1186 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1245
Query: 882 TV 883
+V
Sbjct: 1246 SV 1247
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 561 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 618
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 619 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 673
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 674 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 724
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 725 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 781
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 782 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 836
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 837 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 889
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 890 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 941
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 942 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 999
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 1000 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1058
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1059 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1113
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1114 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1173
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1174 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1233
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1234 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1265
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 643 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 702
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 703 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 758
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 759 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 805
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 806 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 865
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 866 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 925
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 926 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 979
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 980 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1035
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1036 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1087
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1088 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1145
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1146 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1204
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1205 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1249
Score = 169 bits (429), Expect = 5e-41
Identities = 196/756 (25%), Positives = 323/756 (42%), Gaps = 74/756 (9%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 114 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 173
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 174 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 230
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 231 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 290
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 291 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 350
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 351 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 410
Query: 3205 ENAPSGTTV---------IHLNATDAD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITT 3252
E+AP G T+ + + A D D T + + + +F + T +T
Sbjct: 411 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 470
Query: 3253 QGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAP 3312
+D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y +
Sbjct: 471 LQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMR 528
Query: 3313 KGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++ +L
Sbjct: 529 PGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALT 587
Query: 3373 VLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFD 3430
V A + TV + VL N+ PP F +YS++ISE + +G + + A D
Sbjct: 588 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 647
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 3490
+ +Y I +G+ F+++ TG +T+ LDRE+ Y L + A D G P
Sbjct: 648 REG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 702
Query: 3491 TGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
T +A++ + + D+NDN P+ + + + V +++TDPD N G Y
Sbjct: 703 TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY-- 759
Query: 3549 LSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQ 3607
S G + F +++ G + T +++RE + D+Y L VV D V ST T+ I V+D
Sbjct: 760 -SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDI 817
Query: 3608 NDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
+DN V NL G + ++ +D D+
Sbjct: 818 DDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 853
Score = 153 bits (387), Expect = 4e-36
Identities = 184/709 (25%), Positives = 296/709 (41%), Gaps = 90/709 (12%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 198 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 317
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 318 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 377
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 378 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 437
Query: 3327 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGA 3384
+ + +F N F + + Y++ + +DRE+++ + + A F ++
Sbjct: 438 IEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ-- 493
Query: 3385 DIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYF 3443
+ + V VN+ V+DAND P F Y V + + G V ++A D+D S +Y
Sbjct: 494 ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYE 552
Query: 3444 IGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDI 3503
I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E +
Sbjct: 553 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 611
Query: 3504 NDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY 3557
N P L S E+ E R G +++ LQ+TD +G Y + G
Sbjct: 612 PPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRV 665
Query: 3558 FSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----P 3611
F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P
Sbjct: 666 FNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDP 724
Query: 3612 SQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCD 3667
R + + V N F +G VK DPD + H SL +LF I G
Sbjct: 725 YLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYT 778
Query: 3668 LNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
R ++L V++ DG HST+T I+V ++ NS
Sbjct: 779 AVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 827
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 338 bits (868), Expect = 6e-92
Identities = 319/1197 (26%), Positives = 532/1197 (44%), Gaps = 138/1197 (11%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 104 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 161
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPE------SGDLIA 1798
E G+ I A D D+G N + Y I DD D +G+++
Sbjct: 162 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNIVL 221
Query: 1799 TRRLDRERRSKYSLLVRADDGLQSSDMR------INITVSDVNDHTPKF----------- 1841
+RL+ E +++Y ++++A+D Q+ + R + + V D +D P F
Sbjct: 222 RKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRD 281
Query: 1842 SRPV-YSFDIPEDTIPGSLVAAIL-----ATDDDSGVNGE-----ITYIV---NEDDEDG 1887
RP+ Y IPE P L I+ A D D + I Y + +D
Sbjct: 282 CRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPR 341
Query: 1888 IFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTI--RVYFNILDVNDNPPIFS 1945
F ++P T +L ++ + Q + L ++AE G ++ ILD N+ P F+
Sbjct: 342 FFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFT 401
Query: 1946 LNSYSTSLMENLPVGSTVL-VFNVT----------DADDGINSQLTYS-----IASGDSL 1989
+ SY ++E+ PVG+T+ N+T D +D S + + D
Sbjct: 402 MPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDVPPSGVPTKDPELHLFLNDYT 461
Query: 1990 GQFTVDKNGV---LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVND 2046
FTV + G+ L +L+ +DRE Q Y + D Q + V+I ++D ND
Sbjct: 462 SVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQE-----SEPVIVNIQVMDAND 516
Query: 2047 NPPTFLSPKLTY----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTI 2102
N PTF P+++Y + P D+V+ + A D D G N I Y +L F I
Sbjct: 517 NTPTF--PEISYDVYVYTDMRPGDSVI-QLTAVDADEGSNGEITYEILVGAQGDFIINKT 573
Query: 2103 DGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNN---PIFAQALY 2159
G + + ++ Y LTV A D P+ ++ V + + NN P F Q +Y
Sbjct: 574 TGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMY 633
Query: 2160 KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDR 2219
+EI+E G ++ + A D + + Y I NG+ + F + TG +T+ K LDR
Sbjct: 634 SLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDR 690
Query: 2220 EKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT- 2278
E T Y L + A+D G T T+TV+IV+ D+ND PVF+ PY +P NL +
Sbjct: 691 ESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD--PY---LPRNLSVVEEEA 744
Query: 2279 ---ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMIT 2335
+ QV A D D G N ++ Y L GN +N F ++++G + L+RE ++ + L++
Sbjct: 745 NAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVV 802
Query: 2336 ATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASK 2395
ATD T T+ + V D++DN P F + Y + E+ P GT +L + A D D
Sbjct: 803 ATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGA 862
Query: 2396 NAVIRIIGGNSQ--FTINPSTGQIITSALLDRET----KDNYTLVVVCSDAGSPEPLSSS 2449
N RI + F ++P TG++ LD E + + T +V D P +
Sbjct: 863 NVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIA 922
Query: 2450 TSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG--PNSELHYSLSG 2507
T V V V D+ND PP F Y + + G+ + V DAD P S + Y +
Sbjct: 923 T-VTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDD 981
Query: 2508 RN----SEKFHIDPLRGAIMAAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNK 2561
+ F ++ G ++ LN F + V D G + S TV + ++
Sbjct: 982 VQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHP 1041
Query: 2562 ADFPKVRAKEQTFMFPENQPVSSLVTT-----ITGSSLRGEPMSYYIASGNLGNTFQIDQ 2616
+ P+ +E PVS L T + ++ + + Y I SGN +TF I+
Sbjct: 1042 GEIPRFTQEEY-----RPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINN 1096
Query: 2617 LTGQVSISQPLDFEKIQKYVVWIEA-------RDGGFPPFSSYEKLDITVLDVNDNAPIF 2669
+TG + ++ PLD+E YV+ ++A + P S+ K+ I + D N++ P+F
Sbjct: 1097 ITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVF 1156
Query: 2670 KEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIVNGNM---ENSFSINHATGEI 2725
++ +I + E+ +L V A DKD+G + Y ++ + + F + TG I
Sbjct: 1157 QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLI 1216
Query: 2726 RSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVP 2782
++ + S++ + ++D S V+++++++ D Q+ ++VP
Sbjct: 1217 KTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD-----MQVIVSNVP 1268
Score = 326 bits (835), Expect = 4e-88
Identities = 299/1116 (26%), Positives = 504/1116 (45%), Gaps = 95/1116 (8%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 140 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 199
Query: 518 NGLGWFHISEHSGLVTTGS---SGGLDRELASQIVLNISARDQGVH---PKVSYAQLVVT 571
+ + L+ TG+ L+ E ++ + I A D+ + + + L V
Sbjct: 200 PDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVD 259
Query: 572 LLDVNDEKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-- 613
+LD +D P+F +P Y ++ E P ++ ++A D D
Sbjct: 260 VLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQ 319
Query: 614 ---DNGTVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPP 668
D + +S+ E R F + P + LS + ++R+ + L++ A P
Sbjct: 320 PPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP 379
Query: 669 QSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYIT-TVSATDP----------- 716
+ A +++ +LD N+ SP F Y +I E+ P G+ I+ +++ T P
Sbjct: 380 LPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIE 439
Query: 717 DLGTNGTV----KYSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGG 769
D+ +G + + D + Q+G+ ++ +DREE+ Y I A DG
Sbjct: 440 DVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG- 498
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--IS 827
+Q IV I V+D DN P F +++Y V+ ++ G V ++A D SN I+
Sbjct: 499 -VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEIT 557
Query: 828 YLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL- 886
Y I G Q G F IN+ TG +T A ++ Y L V A+ + +I +
Sbjct: 558 YEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIE 616
Query: 887 -----NDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLF 940
N + P F Q + S+ + E + G + +A D + + Y+++ +P+ +F
Sbjct: 617 VLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVF 673
Query: 941 AINEKNGTISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLS 1000
++E G ++L LD + I I+ + G P +S+ + + V DVNDN+PVFD
Sbjct: 674 NLSETTGILTLGKALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYL 733
Query: 1001 YEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDR 1060
E N+ +V+A+D D+G NG++ Y++ GN + F I +G +Y +L+R
Sbjct: 734 PRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNR 791
Query: 1061 ELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVG 1120
E++D Y L+VVA+D AV P +T+ + + + D++DN P+F ++ YT EE AG+ +
Sbjct: 792 EVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTIL 851
Query: 1121 KVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
++ A D D G N R V+ F LH +GE++ D E+ + + F
Sbjct: 852 QIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAF 911
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEG 1240
+P + ATV V +KD+ND P F K Y+ ++ A T + V A D D
Sbjct: 912 DIYGTMPPGI---ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP- 967
Query: 1241 NNGLIHYSIIKGNEERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTI 1293
GL + ++ Q F ++ SG+V L+ E T + LV+ A D G
Sbjct: 968 -PGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEP 1026
Query: 1294 PLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYS 1353
++S+ T+ I +L + + V E G +V ++A + N + YS
Sbjct: 1027 VMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYS 1082
Query: 1354 ITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSV 1406
I N TF I+ TG I++ LD+ET++ Y L + A + P +S+T V
Sbjct: 1083 IVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKV 1142
Query: 1407 VIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPR 1465
I ++D N++PP F + E+ + TSV+ V A D D ++Y II +
Sbjct: 1143 YIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKE 1202
Query: 1466 GNH-FTIDEVKGTIYTNAEIDREFANLFELTVKAND 1500
G F ++ G I T + F+ V A D
Sbjct: 1203 GKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATD 1238
Score = 296 bits (757), Expect = 4e-79
Identities = 307/1147 (26%), Positives = 503/1147 (43%), Gaps = 128/1147 (11%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVIL-----DTATDSDIGSNGVDHRSY 174
EVR++VRD NDN+P F S T E + G + + ATD D G NG
Sbjct: 137 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 196
Query: 175 RIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGE---PKRR 231
+ + +I L +G ++V + L+ E +Y ++++ D+ + +R
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTG-----NIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRT 251
Query: 232 GYLQVNVTVQDINDNPPVF------------GSSHYQAGVPE-------DAVVGSSVLQV 272
+ V V D +D P+F YQA +PE + ++ + +Q
Sbjct: 252 TTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQA 311
Query: 273 AAADADEGTNAD---IRYRLQDEGTP------FQMDPETGLITVREPLDFEARRQYSLTV 323
D + +D I Y + GTP F M P T +++ EP++ + +++ L +
Sbjct: 312 IDQDRNIQPPSDRPGILYSIL-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVI 370
Query: 324 QA-MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVA---- 378
+A D G P L A I++LD N+ P YF S + E+A VG ++
Sbjct: 371 KAEQDNGHP-LPAFAGLHIEILDENNQSP-----YFTMPSYQGYILESAPVGATISDSLN 424
Query: 379 -----LLTVTDAD------SPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ D D S + + + + F V + + + + +D
Sbjct: 425 LTSPLRIVALDKDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITR--YLTLLQPVD 482
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE +Y +++ D S + I V D ND+ P F + Y V + +
Sbjct: 483 REEQQTYTFSITAFDGV---------QESEPVIVNIQVMDANDNTPTFPEISYDVYVYTD 533
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQ 547
PG V ++A D D G N + Y I+ G G F I++ +GL+T + G++ +
Sbjct: 534 MRPGDSVIQLTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMIVGRT 590
Query: 548 IVLNISARDQG--VHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLML 605
L + A D + S + + +L N++ P Y + + E G LL L
Sbjct: 591 YALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNL 650
Query: 606 RATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
+ATD + GD ++ ++++ + +R F L +G L+ +LDRE Y L++ A+D G
Sbjct: 651 QATDRE-GD--SITYAIENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITASD-G 705
Query: 666 SPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVK 725
P +S A +N+ + D+NDN+PVF P E +++ V ATDPD G NG V
Sbjct: 706 RPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVH 765
Query: 726 YSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLD 785
YS+ G+ + +G I T + L+RE + Y+L +VATDG + + I VLD
Sbjct: 766 YSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLD 823
Query: 786 TQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVT 845
DN PVF+ Y+ +V EN+ G + + A +DL +N+SY I + + K FA++ T
Sbjct: 824 IDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFT 883
Query: 846 GQLTTANVI------DREEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFLQAIE 898
G+L+ + D+E + ++ GT+ G V + VKD+ND P F + I
Sbjct: 884 GELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIY 943
Query: 899 SVNVVENWQAGHSI--FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGTISLL 952
V + G I A+ DP V Y + P ++F + E +G +
Sbjct: 944 KGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITR 1003
Query: 953 GPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLSESEP 1010
L+ + +++ ++A D G P +SSS + + V + P F Q Y +SE
Sbjct: 1004 VNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELAT 1062
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLM 1069
+ + A + N I Y+I GN D FGI G +Y+ LD E + YVL
Sbjct: 1063 KGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR 1118
Query: 1070 -------VVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKV 1122
VV ++ V S T V + ++D N++ P+F Y E+ R + V +V
Sbjct: 1119 VQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRV 1178
Query: 1123 SAVDKDFGPNGEVRYSFEMVQP------DFELHAISGEITNTHQFDRESLMRRRGTAVFS 1176
A DKD G + Y ++ P F + +G I F MRR + F
Sbjct: 1179 KATDKDTGNYSVMAYRL-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR---SYFK 1231
Query: 1177 FTVIATD 1183
F VIATD
Sbjct: 1232 FQVIATD 1238
Score = 288 bits (736), Expect = 1e-76
Identities = 287/1080 (26%), Positives = 474/1080 (43%), Gaps = 107/1080 (9%)
Query: 2610 NTFQID-QLTGQVSISQPLDFEKIQKYVVWIEARDGGF---PPFSSYEKLDITVLDVNDN 2665
+TF+I LTG + + + L++E +Y V I+A D ++ L + VLD +D
Sbjct: 207 DTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDL 266
Query: 2666 APIF------------KEDPFISEILENLSPRK----ILT--VSAMDKDSGPNGQLD--- 2704
P+F + + + I E +P + I+T + A+D+D D
Sbjct: 267 GPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPG 326
Query: 2705 --YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKV 2759
Y I+ G E+ F ++ T E+ + P++R+ + L IK+ +
Sbjct: 327 ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGL 386
Query: 2760 MINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT---------RVTTSDEDIGINAISRY 2809
I ILDEN+ +P F+ + ++ E++P+G T++ R+ D+DI S
Sbjct: 387 HIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDVPPSGV 446
Query: 2810 SIMDASLPFTINPSTGDIVISR-----------PLNREDTDRYRIRVSAHDSGW-TVSTD 2857
D L +N T +++ P++RE+ Y ++A D +
Sbjct: 447 PTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVI 506
Query: 2858 VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFY--FIKSQS 2915
V I V D NDN P F SY + G V Q+ A D DEGSNG++ Y + +Q
Sbjct: 507 VNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQG 566
Query: 2916 EYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIV- 2974
++ IN TTG I G + ++ V ++D P+ + T+ I
Sbjct: 567 DFI-INKTTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEV 617
Query: 2975 --DSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKF 3032
+N + P+F + Y +++ ++VG L+ + A D + + Y I N + F
Sbjct: 618 LPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVF 673
Query: 3033 KLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQS 3092
L TG +++ +L + + + +TA D G P +S ATV+I VT+ N + P F
Sbjct: 674 NLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPY 732
Query: 3093 HMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKAL 3152
+ V V A D DA +NG + YS+ GN +F I S+ I T K L
Sbjct: 733 LPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVK-L 789
Query: 3153 DYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTT 3212
+ E+ +E+ + A DG R ++ + V+D++DNSPVF + Y V EN P+GTT
Sbjct: 790 NREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTT 849
Query: 3213 VIHLNATDADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET----KQSYHLT 3267
++ + A D D G N ++Y ++S + F + P TG ++ LD+E + S
Sbjct: 850 ILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFL 907
Query: 3268 VKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDL 3327
V+AF++ ATV + +K N+Y P F ++Y ++ A KGT + V+A D D
Sbjct: 908 VEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP 967
Query: 3328 G--TDGEVHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIR 3382
V Y + F++ + +G++ L+ E L V+A F
Sbjct: 968 PGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVA--FDDGE 1025
Query: 3383 GADIDEVTVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFDSDSIPSWSRFS 3441
TV + VL + P FT Y +SE GT V +SA +
Sbjct: 1026 PVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAAIN-----QSIV 1080
Query: 3442 YFIGSGNENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAVDSGTPSATGSA 3494
Y I SGNE F IN TG I V LD ET Y +L V+ + PS + +A
Sbjct: 1081 YSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTA 1140
Query: 3495 SLLVTLEDINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLL--S 3550
+ + ++D N++ P+ G V E+ R T V+ +++TD D N Y L+
Sbjct: 1141 KVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNYSVMAYRLIIPP 1199
Query: 3551 TGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQND 3609
F + T G++ T + + F V+ D +S V ++V++Q D
Sbjct: 1200 IKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLD 1259
Score = 282 bits (722), Expect = 5e-75
Identities = 254/852 (29%), Positives = 385/852 (45%), Gaps = 78/852 (9%)
Query: 190 TLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGYLQVNVTVQDINDN 246
T+ +G +L L+ +DRE Y + D + EP + VN+ V D NDN
Sbjct: 465 TVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP-----VIVNIQVMDANDN 517
Query: 247 PPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDEGTPFQMDPETGLI 305
P F Y V D G SV+Q+ A DADEG+N +I Y L F ++ TGLI
Sbjct: 518 TPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLI 577
Query: 306 TVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDNDPVVKFRYFPATSR 363
T+ ++ R Y+LTVQA D P+ I++L N+ P FP
Sbjct: 578 TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP----PRFPQLMY 633
Query: 364 YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
+ E +VG V+ L TD + +I+ I G+ QR F + + ++ +
Sbjct: 634 SLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLSET----TGILTLG 685
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
ALDRE Y L ++ SD G P G +S A++ I V D+ND+ PVF + R
Sbjct: 686 KALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVNDNAPVFDPYLPRNL 737
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
E ++V + ATD D+G+N + YS+ + N L F I+ + + T L+RE
Sbjct: 738 SVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGSIYTAVK---LNRE 792
Query: 544 LASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELL 603
+ L + A D VHP+ S L + +LD++D PVF+ Y V V EN P GT +L
Sbjct: 793 VRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTVLVEENLPAGTTIL 851
Query: 604 MLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE----EQAFYSLLV 659
+ A D DLG N + R E + F L P +G LS + SLD E ++A + LV
Sbjct: 852 QIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYEAFPDQEASITFLV 908
Query: 660 LATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLG 719
A D+ +A + V + D+ND PVF Y + + G+ ITTV A D D
Sbjct: 909 EAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPP 968
Query: 720 --TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQS 773
V+Y + S F+V SG + TR+ L+ E T ++L +VA D G
Sbjct: 969 GLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVM 1028
Query: 774 PNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTG 833
+ A V I VL + P + V E G VG +SA+ +N +I Y I +G
Sbjct: 1029 SSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA--INQSIVYSIVSG 1086
Query: 834 DQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV----------TGDTMVNITV 883
+++ F IN +TG + +D E ++ Y L+V A V + V I +
Sbjct: 1087 NEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEI 1146
Query: 884 KDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNP----KNL 939
+D N++ P F + V E+ + S+ + KA D D G ++ Y L P K
Sbjct: 1147 QDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEG 1206
Query: 940 FAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQ 998
F + G I ++ ++ +++A+D LS + V V +Q
Sbjct: 1207 FVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV---------SVVNQ 1257
Query: 999 LSYEVTLSESEP 1010
L +V +S P
Sbjct: 1258 LDMQVIVSNVPP 1269
Score = 278 bits (712), Expect = 7e-74
Identities = 315/1205 (26%), Positives = 524/1205 (43%), Gaps = 142/1205 (11%)
Query: 820 MDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA------SGGTV 873
+ L N+ Y + K M +N +T V+DR+ VV GT+
Sbjct: 80 LSLKDNVDYWVLMDPVKQMLFLN------STGRVLDRDPPMNIHSIVVQVQCINKKVGTI 133
Query: 874 TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQA-----KAVDPDEGVNGMV 928
V I V+D NDNSP F V E G +IF A D D+G NG +
Sbjct: 134 IYHE-VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQI 192
Query: 929 LYSLKQNPKNLFAINEKNGTISLLGPLDVH-------AGSYQIEILASDMGV---PQLSS 978
Y ++ NP + + + + L G + + Y + I A+D + ++
Sbjct: 193 EYVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTT 252
Query: 979 SVILTVYVHDVNDNSPVF------------DQLSYEVTLSE---SEPVNSRFF--KVQAS 1021
+ LTV V D +D P+F L+Y+ + E E +N +QA
Sbjct: 253 TTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAI 312
Query: 1022 DKDSGANGE-----IAYTIAEGNTGD---AFGIFP-DGQLYIKSELDRELQDRYVLMVVA 1072
D+D I Y+I G D F + P +L + ++R+ ++ L++ A
Sbjct: 313 DQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKA 372
Query: 1073 SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVG---------KVS 1123
PL A + + + D N+ P F +Y Y E G+ + ++
Sbjct: 373 EQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIV 432
Query: 1124 AVDKDF---GPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMR---------RRG 1171
A+DKD P+G + D ELH + T+ + + R R
Sbjct: 433 ALDKDIEDVPPSG-------VPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREE 485
Query: 1172 TAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLR 1231
++F++ A D G+ + + V++ + D NDN P F + Y + V++
Sbjct: 486 QQTYTFSITAFD-GVQE--SEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ 542
Query: 1232 VSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
++A D DEG+NG I Y I+ G + F I+ T+G +T+ ++ Y+L +QA D+
Sbjct: 543 LTAVDADEGSNGEITYEILVG-AQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNA 601
Query: 1292 --TIPLNSTCTLNIDILDENDNT-PSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNA 1348
NS CT+ I++L N+ + P FP+ +++ E MR+G ++ ++ ATD + GD+
Sbjct: 602 PPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE-GDS- 659
Query: 1349 DLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVI 1408
+ Y+I + F++S TG + L K LD E+ Y L ITA D GRP +ST +V I
Sbjct: 660 -ITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNI 717
Query: 1409 HVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH 1468
V D NDN P F P V V V A DPDA INGQ+ Y++ GN
Sbjct: 718 VVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL------GNF 771
Query: 1469 FTIDEV--KGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNV 1526
+ + G+IYT +++RE + +EL V A D AV R++ + I V D++DN
Sbjct: 772 NNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAV---HPRHSTLTLAIKVLDIDDNS 828
Query: 1527 PMFI-SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDTDTFI-VDRYSGDL 1584
P+F S + + + G+ + I A D D GAN + Y I + + F + ++G+L
Sbjct: 829 PVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGEL 886
Query: 1585 RVASAL----VPSQ-LIYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITI 1637
+ +L P Q +V A D+ +T+I++ ++ PVF++ Y +
Sbjct: 887 SLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGM 946
Query: 1638 LKEGEPIGTNVISI--EAASPRGSEAP-VEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAA 1694
+ GT + ++ E A P G A V Y + V+ +F + +G + T
Sbjct: 947 VAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYP--ASIFEVEEDSGRVITRV 1004
Query: 1695 ILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIG 1754
L+ E LV V A + + A V+I + + P + V E
Sbjct: 1005 NLNEEPTTIFKLV-VVAFDDGEPV-MSSSATVKILVLHPGEIPRFTQEEYRPPPVSELAT 1062
Query: 1755 DGSKIMQLTAMDADEGANALVTYTIISG-ADDSFRIDPESGDLIATRRLDRERRSKYSLL 1813
G+ + ++A N + Y+I+SG +D+F I+ +G + LD E R+ Y L
Sbjct: 1063 KGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR 1118
Query: 1814 VRADD----------GLQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAI 1863
V+AD +S+ ++ I + D N+H P F + Y + ED + V +
Sbjct: 1119 VQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRV 1178
Query: 1864 LATDDDSGVNGEITYIV----NEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAE 1919
ATD D+G + Y + ++ ++G F + TG+ L + Y+ V A
Sbjct: 1179 KATDKDTGNYSVMAYRLIIPPIKEGKEG-FVVETYTGLIKTAMLFHNMRRSYFKFQVIAT 1237
Query: 1920 DGGGQ 1924
D G+
Sbjct: 1238 DDYGK 1242
Score = 273 bits (698), Expect = 3e-72
Identities = 343/1312 (26%), Positives = 567/1312 (43%), Gaps = 148/1312 (11%)
Query: 585 PEGYDVSVVENAPTGTEL---LMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRL 641
P V++ E + GT L ++++ T G G + T+ SL++ D +DPV L
Sbjct: 44 PPATIVAIDEESRNGTILVDNMLIKGTAG--GPDPTIELSLKD-NVDYWVL-MDPVKQML 99
Query: 642 ---STISSLDREEQAFYSLLVLATDLGSPPQSSMA--RINVSLLDINDNSPVFYPVQYFA 696
ST LDR+ +V+ + ++ + + + D NDNSP F Y+A
Sbjct: 100 FLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYA 159
Query: 697 HIKENEPGGSYITT-----VSATDPDLGTNGTVKYSISAG-----DRSRFQVNAQ-SGVI 745
+ E P G+ I T ATD D G NG ++Y I F++ +G I
Sbjct: 160 TVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLMLTGNI 219
Query: 746 STRMALDREEKTAYQLQIVATDGG---NLQSPNQAIVTITVLDTQDNPPVF--------- 793
R L+ E+KT Y + I A D N + +T+ VLD D P+F
Sbjct: 220 VLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNT 279
Query: 794 ---SQVAYSFVVFE---NVALGYHVGSVSASTMDLNSNIS---------YLITTG---DQ 835
+ Y + E L + + +D + NI Y I G D
Sbjct: 280 RDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDY 339
Query: 836 KGMFAINQVTGQLTTANVIDREEQSFYQLKVVA---SGGTVTGDTMVNITVKDLNDNSPH 892
F ++ T +L+ ++R+ + L + A +G + ++I + D N+ SP+
Sbjct: 340 PRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPY 399
Query: 893 FLQAIESVNVVENWQAGHSI---------FQAKAVD------PDEGV--NGMVLYSLKQN 935
F ++E+ G +I + A+D P GV L+ +
Sbjct: 400 FTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDVPPSGVPTKDPELHLFLND 459
Query: 936 PKNLFAINEKNGT--ISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDN 992
++F + + T ++LL P+D +Y I A D GV Q S VI+ + V D NDN
Sbjct: 460 YTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD-GV-QESEPVIVNIQVMDANDN 517
Query: 993 SPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQL 1052
+P F ++SY+V + ++ A D D G+NGEI Y I G GD G +
Sbjct: 518 TPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLI 577
Query: 1053 YIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDV---NDNRPLFNSTNYTFYF 1109
I ++ + Y L V A+D A TV +E + N + P F Y+
Sbjct: 578 TIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEI 637
Query: 1110 EEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNTHQFDRESLM 1167
E R G+ + + A D++ + Y+ E P F L +G +T DRES
Sbjct: 638 SEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTD 694
Query: 1168 RRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFY---QATISESAA 1224
R +I G P ATV++ + D+NDNAP F D Y ++ E A
Sbjct: 695 R-------YILIITASDGRPDG-TSTATVNIVVTDVNDNAPVF--DPYLPRNLSVVEEEA 744
Query: 1225 NLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLV 1284
N V +V A+D D G NG +HYS+ GN F I S +G + KL+ E Y LV
Sbjct: 745 N-AFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITS-NGSIYTAVKLNREVRDYYELV 800
Query: 1285 IQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDS 1344
+ A D P +ST TL I +LD +DN+P F ST V V EN+ G + + A D D
Sbjct: 801 VVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 860
Query: 1345 GDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQG------RP 1398
G A++ Y I F++ P TG + L + LD+E + +IT + P
Sbjct: 861 G--ANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMP 918
Query: 1399 PRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI-GTSVISVTAHDPDAD--INGQL 1455
P +T++V+ V+D ND PP F I+K +V + GT + +V A D D ++
Sbjct: 919 PGIATVTVI--VKDMNDYPPVFSK-RIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRV 975
Query: 1456 SYTI--IQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALK 1513
Y + +Q + F ++E G + T ++ E +F+L V A D P+ + +K
Sbjct: 976 RYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVK 1035
Query: 1514 NVTILVTDLNDNVPMFISQNALAADPS--AVIGSVLTTIMAADPDEGANGEIEYEIING- 1570
ILV + +P F + S A G+++ I AA N I Y I++G
Sbjct: 1036 ---ILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA----AINQSIVYSIVSGN 1087
Query: 1571 DTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSA-------TDLGPERRKSTTELTIILQ 1622
+ DTF ++ +G + V L ++ Y L V A +L + +T ++ I +Q
Sbjct: 1088 EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQ 1147
Query: 1623 GLDG--PVFTQPKYITILKEGEPIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGR 1679
+ PVF + YI + E + T+V+ ++A G+ + + Y ++ +E G
Sbjct: 1148 DENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEG- 1206
Query: 1680 LFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDIND-NPP 1738
F + +TG+I+TA + + + + + + + + + ++ + +N +
Sbjct: 1207 -FVVETYTGLIKTAMLFHNMRRSYF----KFQVIATDDYGKGLSGKADVLVSVVNQLDMQ 1261
Query: 1739 VFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRID 1790
V +++ VE+ I D ++I+ + GA +V D+F ++
Sbjct: 1262 VIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAFSLE 1313
Score = 266 bits (681), Expect = 3e-70
Identities = 322/1154 (27%), Positives = 503/1154 (43%), Gaps = 132/1154 (11%)
Query: 779 VTITVLDTQDNPPVFSQVAYSFVVFENVALGYHV-----GSVSASTMD--LNSNISYLIT 831
V I V D DN P F +Y V E +G + G A+ +D N I Y+I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 832 TG----DQKGMFAIN-QVTGQLTTANVIDREEQSFYQLKVVASGGTV------TGDTMVN 880
F I +TG + ++ E+++ Y + + A+ T T +
Sbjct: 198 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 881 ITVKDLNDNSPHFLQAI-----------------------ESVNVVENWQAGHSIFQAKA 917
+ V D +D P FL + E +N + +I Q +
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 317
Query: 918 VDPDEGVNGMVLYSLKQNPKN---LFAINEKNGTISLLGPL--DVHAGSYQIEILASDMG 972
+ P G++ L P++ F ++ + +SLL P+ D H + + I A
Sbjct: 318 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQ-KFDLVIKAEQDN 376
Query: 973 VPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRF---------FKVQASDK 1023
L + L + + D N+ SP F SY+ + ES PV + ++ A DK
Sbjct: 377 GHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDK 436
Query: 1024 D------SGA-NGEIAYTIAEGNTGDAFGIFPDG---QLYIKSELDRELQDRYVLMVVAS 1073
D SG + + + F + G L + +DRE Q Y + A
Sbjct: 437 DIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAF 496
Query: 1074 DRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNG 1133
D E VN+ V+ D NDN P F +Y Y + R G V +++AVD D G NG
Sbjct: 497 DGVQESEPVIVNIQVM--DANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG 554
Query: 1134 EVRYSFEM-VQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD 1192
E+ Y + Q DF ++ +G IT E ++ R ++ TV A D P ++
Sbjct: 555 EITYEILVGAQGDFIINKTTGLITIAPGV--EMIVGR----TYALTVQAADNAPPAERRN 608
Query: 1193 Q-ATVHV-YMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSII 1250
TV++ + N + P+F + Y ISE+ +L + A+D EG++ I Y+I
Sbjct: 609 SICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD-REGDS--ITYAIE 665
Query: 1251 KGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDEND 1310
G+ +R F + T+G +TL LD E+T Y L+I A D G ST T+NI + D ND
Sbjct: 666 NGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVND 724
Query: 1311 NTPSF----PKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSIS 1366
N P F P++ V+ N +G+ V ATD D+G N ++YS+ NN F I+
Sbjct: 725 NAPVFDPYLPRNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSLGNFNN--LFRIT 778
Query: 1367 PNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIF 1426
N GSI+ A KL+ E + Y+L + A D PR ST+++ I V D +DN P F
Sbjct: 779 SN-GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYT 837
Query: 1427 KSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNH-FTIDEVKGTIYTNAEID 1485
+ EN+P GT+++ + A D D+ +SY I + P H F + G + +D
Sbjct: 838 VLVEENLPAGTTILQIEA--KDVDLGANVSYRI--RSPEVKHFFALHPFTGELSLLRSLD 893
Query: 1486 REFANLFELTVKANDQAVPI-ETRRYALKNVTILVTDLNDNVPMF---ISQNALAADPSA 1541
E E ++ +A I T + VT++V D+ND P+F I + +A P A
Sbjct: 894 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVA--PDA 951
Query: 1542 VIGSVLTTIMA--ADPDEGANGEIEYEIINGD----TDTFIVDRYSGDL--RVASALVPS 1593
V G+ +TT+ A ADP + Y + + F V+ SG + RV P+
Sbjct: 952 VKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPT 1011
Query: 1594 QLIYNLIVSATDLGPERRKSTTELTIILQGLDGPVFTQPKY-ITILKEGEPIGTNVISIE 1652
+ ++V+ D P S T ++L + P FTQ +Y + E GT V I
Sbjct: 1012 TIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVIS 1071
Query: 1653 AASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYL-VDVYA 1711
AA+ S + Y IVS EE T G I TG+I LD E L V +
Sbjct: 1072 AAAINQS---IVYSIVSGN-EEDTFG----INNITGVIYVNGPLDYETRTSYVLRVQADS 1123
Query: 1712 IEKSTAFPR----TQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDA 1767
+E A R + A+V I +QD N++PPVF V E+ + ++++ A D
Sbjct: 1124 LEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDK 1183
Query: 1768 DEGANALVTYTI----ISGADDSFRIDPESGDLIATRRLDRERRSKY--SLLVRADDGLQ 1821
D G +++ Y + I + F ++ +G LI T L R Y ++ DD +
Sbjct: 1184 DTGNYSVMAYRLIIPPIKEGKEGFVVETYTG-LIKTAMLFHNMRRSYFKFQVIATDDYGK 1242
Query: 1822 SSDMRINITVSDVN 1835
+ ++ VS VN
Sbjct: 1243 GLSGKADVLVSVVN 1256
Score = 265 bits (676), Expect = 1e-69
Identities = 283/1049 (26%), Positives = 474/1049 (45%), Gaps = 119/1049 (11%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 193
Query: 2705 YEIV----NGNMENSFSIN-HATGEIRSVRPLDREKVSHYVLTIKSSDKG---SPSQSTS 2756
Y I + ++F I TG I + L+ E + Y + I+++D+ + ++T+
Sbjct: 194 YVIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTT 253
Query: 2757 VKVMINILDENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----D 2798
+ +++LD +D P F + A +PE +P VT D
Sbjct: 254 TTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAID 313
Query: 2799 EDIGINAISR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH 2848
+D I S YSI+ D F ++P T ++ + P+NR+ ++ + + A
Sbjct: 314 QDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAE 373
Query: 2849 -DSGWTVST--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFA 2896
D+G + + I + D N+ +P F+ SY E +G+ ++ ++ A
Sbjct: 374 QDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVA 433
Query: 2897 TDPD---------EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNIN 2947
D D + ++ F+ + F + T + + Q V
Sbjct: 434 LDKDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQ 487
Query: 2948 RHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTA 3007
++F +T+ D + S V I ++D+NDN P F + Y V +++ G +I++TA
Sbjct: 488 TYTFSITAFDGVQES--EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 545
Query: 3008 IDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNP 3067
+D D G N E+ Y I G F ++ TG I++A + + + + +TV A D P
Sbjct: 546 VD-ADEGSNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPP 603
Query: 3068 P--LSSQATVHITVTEENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLI 3124
+S TV+I V N +P F Q S I E+ +G+++ + A DR+ I
Sbjct: 604 AERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---I 660
Query: 3125 KYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNV 3184
Y+I +G+ + +F ++ +TGILTL KALD E ++ + I+A DG G + TVN+
Sbjct: 661 TYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNI 717
Query: 3185 I--DVNDNSPVFLSDDYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDL 3240
+ DVNDN+PVF D Y P L + V + ATD D+G N + Y++ + ++L
Sbjct: 718 VVTDVNDNAPVF--DPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNL 774
Query: 3241 FVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS 3300
F I N G I T L+ E + Y L V A + R S T+ I++ ++ P F +
Sbjct: 775 FRITSN-GSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN 833
Query: 3301 KLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI 3360
Y + E P GT + ++ A D DLG + V Y I K F ++ TG++ +
Sbjct: 834 STYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRS 891
Query: 3361 LDREK--EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGV 3417
LD E ++ S+ L + F TV V V D ND PP+F+ IY ++
Sbjct: 892 LDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDA 951
Query: 3418 PIGTHVTFVSAFDSD--SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRET 3472
GT +T V A D+D +P+ SR Y + F + +G++ L+ E
Sbjct: 952 VKGTPITTVYAEDADPPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEP 1010
Query: 3473 LPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMT 3529
I+ L V+A D G P + SA++ + + + P T E V E GT+V
Sbjct: 1011 TTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGV 1069
Query: 3530 LQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL------- 3582
+ + NQ Y ++S ++ + GV+ +D E + L
Sbjct: 1070 ISAA----AINQS-IVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSL 1124
Query: 3583 SVVTKDSGVPQMSSTGTVHITVIDQNDNP 3611
VV + VP S+T V+I + D+N++P
Sbjct: 1125 EVVLANLRVPSKSNTAKVYIEIQDENNHP 1153
Score = 258 bits (658), Expect = 1e-67
Identities = 304/1164 (26%), Positives = 500/1164 (42%), Gaps = 140/1164 (12%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y +I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-VI 196
Query: 1251 KGNEERQFAIDS------TSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLN----STCT 1300
+ N + + D+ +G + L +L+YE Y ++IQA D LN +T T
Sbjct: 197 QYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQ-NLNERRTTTTT 255
Query: 1301 LNIDILDENDNTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSD 1343
L +D+LD +D P F L + + +R E ++ + T D D
Sbjct: 256 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 315
Query: 1344 SG-----DNADLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQ 1395
D + YSI T + F + P T + L + ++ + + L I A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 1396 GRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVI-SVTAHDP------D 1448
P + + I + D N+ P F I+E+ P+G ++ S+ P D
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 1449 ADINGQLSYTIIQQMPR--------GNHFTIDEVKGTIYTNA--EIDREFANLFELTVKA 1498
DI + + P + FT+ + T Y +DRE + ++ A
Sbjct: 436 KDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA 495
Query: 1499 NDQAVPIETRRYALKNVTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPD 1556
D E V I V D NDN P F IS + SV+ + A D D
Sbjct: 496 FDGVQESEP-----VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDAD 549
Query: 1557 EGANGEIEYEIINGDTDTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTT 1615
EG+NGEI YEI+ G FI+++ +G + +A + + Y L V A D P + +
Sbjct: 550 EGSNGEITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNS 609
Query: 1616 ELTIILQGL-----DGPVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSV 1670
T+ ++ L P F Q Y + E +G +++++A G ++
Sbjct: 610 ICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITY 662
Query: 1671 RCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEIT 1729
E R+F + TGI+ LDRE L+ I S P T A V I
Sbjct: 663 AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIV 718
Query: 1730 LQDINDNPPVF-PTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFR 1788
+ D+NDN PVF P +L+V E + + + Q+ A D D G N V Y+ + ++ FR
Sbjct: 719 VTDVNDNAPVFDPYLPRNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFR 776
Query: 1789 IDPESGDLIATRRLDRERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPV 1845
I +G + +L+RE R Y L+V A DG + S + + I V D++D++P F+
Sbjct: 777 I-TSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 835
Query: 1846 YSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLD 1905
Y+ + E+ G+ + I A D D G N ++Y + + F L+P TG +L R LD
Sbjct: 836 YTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLD 893
Query: 1906 YEV----QQYYILTVRAEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENL 1957
YE + V A D G T+ V + D+ND PP+FS Y + +
Sbjct: 894 YEAFPDQEASITFLVEAFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDA 951
Query: 1958 PVGSTVLVFNVTDAD-DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRES 2010
G+ + DAD G+ S++ Y + S+ + D V+ + L+ E
Sbjct: 952 VKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEP 1010
Query: 2011 QSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVF 2070
+ + LVV D + S S+A V I++L + P F + Y P P+ +
Sbjct: 1011 TTIFKLVVVAFDDGEPVMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELAT 1062
Query: 2071 KAQATDPDSGP--NSYIEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY----- 2120
K S N I Y++++ GN+ F I I G + + G LD E ++Y
Sbjct: 1063 KGTMVGVISAAAINQSIVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1120
Query: 2121 --TLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFA 2178
+L VV + PS S++ +V + + D N++ P+F + Y ++E+ T +++V A
Sbjct: 1121 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1180
Query: 2179 ADGDEGTNGQVRYGIV---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD-- 2233
D D G + Y ++ + F +++ TG I A + + V ATD
Sbjct: 1181 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1240
Query: 2234 -RGSTPRTDTSTVSIVLLDINDFV 2256
+G + + D + LD+ V
Sbjct: 1241 GKGLSGKADVLVSVVNQLDMQVIV 1264
Score = 249 bits (636), Expect = 5e-65
Identities = 288/1098 (26%), Positives = 466/1098 (42%), Gaps = 116/1098 (10%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 135 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 194
Query: 288 RLQ-DEGTPFQMDP------ETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEAL 340
+Q + P D TG I +R+ L++E + +Y + +QA DR R
Sbjct: 195 VIQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTT 254
Query: 341 IQLLDVNDND-------------------PVVKFRYFPATSRYASVDENAQVGTVVALLT 381
+DV D D P+ P ++ + A+
Sbjct: 255 TLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQ 314
Query: 382 VTDADSPAANGNISVQILGGNEQ---RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTV 438
+ P+ I IL G + R F + P + + + ++R+ ++L +
Sbjct: 315 DRNIQPPSDRPGILYSILVGTPEDYPRFFHMH----PRTAELSLLEPVNRDFHQKFDLVI 370
Query: 439 SVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVS-GI 497
+ G P A A L I + D N+ P F+ Y+ + E AP G+ +S +
Sbjct: 371 KAEQDNGHPLPA-------FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSL 423
Query: 498 SATDGDSGLNANLRYSIVSGNGLG------WFHISEHSGLVTTGSSG---------GLDR 542
+ T + + V +G+ +++++ + T +G +DR
Sbjct: 424 NLTSPLRIVALDKDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDR 483
Query: 543 ELASQIVLNISARD--QGVHPKVSYAQLVVTLLDVNDEKPVFSQPE-GYDVSVVENAPTG 599
E +I+A D Q P + + + ++D ND P F PE YDV V + G
Sbjct: 484 EEQQTYTFSITAFDGVQESEPVI----VNIQVMDANDNTPTF--PEISYDVYVYTDMRPG 537
Query: 600 TELLMLRATDGDLGDNGTVRFS-LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLL 658
++ L A D D G NG + + L A+ D F ++ +G ++ ++ Y+L
Sbjct: 538 DSVIQLTAVDADEGSNGEITYEILVGAQGD---FIINKTTGLITIAPGVEMIVGRTYALT 594
Query: 659 VLATDLGSPPQ--SSMARINVSLLDINDNSPVFYP-VQYFAHIKENEPGGSYITTVSATD 715
V A D P + +S+ + + +L N+ SP +P + Y I E G+ + + ATD
Sbjct: 595 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 654
Query: 716 PDLGTNGTVKYSISAGDRSR-FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSP 774
+ ++ Y+I GD R F ++ +G+++ ALDRE Y L I A+D G
Sbjct: 655 RE---GDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGT 710
Query: 775 NQAIVTITVLDTQDNPPVFS-QVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTG 833
+ A V I V D DN PVF + + V E A + VG V A+ D N + G
Sbjct: 711 STATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSLG 769
Query: 834 DQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLNDNS 890
+ +F I G + TA ++RE + +Y+L VVA+ G V + I V D++DNS
Sbjct: 770 NFNNLFRITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNS 828
Query: 891 PHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTI 949
P F + +V V EN AG +I Q +A D D G N V Y ++ K+ FA++ G +
Sbjct: 829 PVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGEL 886
Query: 950 SLLGPLDVHA-----GSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVT 1004
SLL LD A S + A D+ +TV V D+ND PVF + Y+
Sbjct: 887 SLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGM 946
Query: 1005 LSESEPVNSRFFKVQASDKDSGA--NGEIAYTIAEGNTGDAFGIF----PDGQLYIKSEL 1058
++ + V A D D + Y + + IF G++ + L
Sbjct: 947 VAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNL 1006
Query: 1059 DRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNY-TFYFEEEQRAGS 1117
+ E + L+VVA D +S++ V +++ + P F Y E G+
Sbjct: 1007 NEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGT 1065
Query: 1118 FVGKVSAVDKDFGPNGEVRYSFEM--VQPDFELHAISGEITNTHQFD---RESLMRRRGT 1172
VG +SA N + YS + F ++ I+G I D R S + R
Sbjct: 1066 MVGVISAA----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLR--V 1119
Query: 1173 AVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV 1232
S V+ + +P + A V++ ++D N++ P F K FY +SE A T VLRV
Sbjct: 1120 QADSLEVVLANLRVPSK-SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRV 1178
Query: 1233 SASDVDEGNNGLIHYSII 1250
A+D D GN ++ Y +I
Sbjct: 1179 KATDKDTGNYSVMAYRLI 1196
Score = 230 bits (587), Expect = 2e-59
Identities = 240/881 (27%), Positives = 382/881 (43%), Gaps = 106/881 (12%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 86 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 145
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 146 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPTS 205
Query: 2921 NAT-------TGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK---PSLISETTVT 2970
N T TG I ++ L Y++ T R+ I+ ++DR + + TT+T
Sbjct: 206 NDTFEIPLMLTGNIVLRKRLNYEDKT--------RYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 2971 INIVDSNDNAPQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-D 3010
++++D +D P FL + TP N + T I+ AID D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQD 315
Query: 3011 KDFGLNSE---VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK 3064
++ S+ + Y I + +++ F + T +S+ + D +Q F + + A+
Sbjct: 316 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 375
Query: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---TVSARDRDAAMN 3121
PL + A +HI + +EN +P F+ I ES +G+ + +++ R A++
Sbjct: 376 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 435
Query: 3122 GLIKYSISSG-------------NEEGIFAINSS--TGILTLAKALDYELCQKHEMTISA 3166
I+ SG + +F + + T LTL + +D E Q + +I+A
Sbjct: 436 KDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA 495
Query: 3167 IDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTN 3226
DG V + V + V+D NDN+P F Y V + G +VI L A DAD G+N
Sbjct: 496 FDG--VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSN 553
Query: 3227 AVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATV 3284
I Y + F+I+ TG+IT ++ ++Y LTV+A + P E R S TV
Sbjct: 554 GEITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTV 613
Query: 3285 NIQ-LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
I+ L N+ PRF +Y EISEA G ++ + A+DR+ + Y I +
Sbjct: 614 YIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQ 670
Query: 3344 KGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND--- 3400
+ F +++ TG + + LDRE +R L + A + R TVN+ V D ND
Sbjct: 671 RVFNLSETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAP 727
Query: 3401 --PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINP 3457
P N+ V+ +G V A D D+ I +S GN N F I
Sbjct: 728 VFDPYLPRNLSVVEEEANAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT- 778
Query: 3458 QTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEV 3517
G I +L+RE Y L V+A D + +L + + DI+DN P+ T S V
Sbjct: 779 SNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTV 838
Query: 3518 M--ENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDR 3574
+ EN GT ++ +++ D DL N Y + + +F+L G LS R +D
Sbjct: 839 LVEENLPAGTTILQIEAKDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDY 894
Query: 3575 EQIADFYLSVV----TKDSGVPQMSSTGTVHITVIDQNDNP 3611
E D S+ D TV + V D ND P
Sbjct: 895 EAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYP 935
Score = 218 bits (555), Expect = 1e-55
Identities = 249/864 (28%), Positives = 380/864 (43%), Gaps = 79/864 (9%)
Query: 52 LEEQPPGTLVGTIQTRPGFTYRLSESHALFAINSSTGALYTT--STIDRESLPSDVINLV 109
+E+ PP G P L++ ++F + + Y T +DRE + ++
Sbjct: 438 IEDVPPS---GVPTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSIT 494
Query: 110 VLSSAP-TYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNG 168
+ P V + V D NDN P FP+ S V D G VI TA D+D GSNG
Sbjct: 495 AFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG 554
Query: 169 VDHRSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEP 228
+Y I+ G + G F ++ T + G++ V Y L V+ D P
Sbjct: 555 --EITYEILVGAQ-GDFIINKTTG--------LITIAPGVEMIVGRTYALTVQAADNAPP 603
Query: 229 KRRGYLQVNVTVQDI---NDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADI 285
R V ++ + N +PP F Y + E VG+ +L + A D EG +
Sbjct: 604 AERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITY 662
Query: 286 RYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLD 345
D F + TG++T+ + LD E+ +Y L + A D G P T A I + D
Sbjct: 663 AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTD 721
Query: 346 VNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQR 405
VNDN PV Y P + NA VG V A TD D+ NG + + GN
Sbjct: 722 VNDNAPVFD-PYLPRNLSVVEEEANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNN 773
Query: 406 HFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFV 465
F + S+ I A L+RE Y L V +D AV R S +L I V
Sbjct: 774 LFRITSN-----GSIYTAVKLNREVRDYYELVVVATD-------GAVHPRHSTLTLAIKV 821
Query: 466 NDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
DI+D+ PVF+ Y V + E P G+ + I A D D L AN+ Y I S +F +
Sbjct: 822 LDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFAL 879
Query: 526 SEHSGLVTTGSSGGLDREL----ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKP 580
+G ++ S LD E + I + A D G P A + V + D+ND P
Sbjct: 880 HPFTGELSLLRS--LDYEAFPDQEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPP 936
Query: 581 VFSQPEGYDVSVVENAPTGTELLMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDP 636
VFS+ Y V +A GT + + A D D VR+ + + + + F ++
Sbjct: 937 VFSK-RIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEE 995
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF- 695
SGR+ T +L+ E + L+V+A D G P SS A + + +L + P F +Y
Sbjct: 996 DSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRP 1054
Query: 696 AHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDRE 754
+ E G+ + +SA N ++ YSI +G + F +N +GVI LD E
Sbjct: 1055 PPVSELATKGTMVGVISAA----AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYE 1110
Query: 755 EKTAYQLQIVATD----GGNLQSP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVA 807
+T+Y L++ A NL+ P N A V I + D ++PPVF + Y V E+
Sbjct: 1111 TRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDAR 1170
Query: 808 LGYHVGSVSASTMDLN--SNISY-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFY 862
+ V V A+ D S ++Y LI ++G F + TG + TA + +S++
Sbjct: 1171 MFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYF 1230
Query: 863 QLKVVAS---GGTVTGDTMVNITV 883
+ +V+A+ G ++G V ++V
Sbjct: 1231 KFQVIATDDYGKGLSGKADVLVSV 1254
Score = 186 bits (471), Expect = 7e-46
Identities = 205/752 (27%), Positives = 325/752 (43%), Gaps = 78/752 (10%)
Query: 81 FAINSSTGALYTTSTIDRESLPSDVINLVVLSSAPTYPTEVR-----VLVRDL---NDNA 132
F IN +TG + ++ + + + +AP P E R V + L N +
Sbjct: 568 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAP--PAERRNSICTVYIEVLPPNNQSP 625
Query: 133 PVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDITLN 192
P FP + E G ++ ATD + D +Y I G+ F L T
Sbjct: 626 PRFPQLMYSLEISEAMRVGAVLLNLQATDRE-----GDSITYAIENGDPQRVFNLSETTG 680
Query: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGS 252
G LDRE T +Y L++ D G P VN+ V D+NDN PVF
Sbjct: 681 ILTLGK--------ALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDP 731
Query: 253 --SHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREP 310
+ V E+A + V QV A D D G N + Y L + F++ G I
Sbjct: 732 YLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAVK 788
Query: 311 LDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDEN 370
L+ E R Y L V A D V I++LD++DN PV F ++ V+EN
Sbjct: 789 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPV-----FTNSTYTVLVEEN 843
Query: 371 AQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRER 430
GT + + D D A N+S +I E +HF LSL++ +LD E
Sbjct: 844 LPAGTTILQIEAKDVDLGA---NVSYRIRSP-EVKHFFALHPFTGELSLLR---SLDYEA 896
Query: 431 IP----SYNLTVSVSDNYGA-PPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLS 485
P S V D YG PPG +A++ + V D+ND+PPVFS+++Y+ ++
Sbjct: 897 FPDQEASITFLVEAFDIYGTMPPG--------IATVTVIVKDMNDYPPVFSKRIYKGMVA 948
Query: 486 EEAPPGSYVSGISATDGDS-GLNAN-LRYSIVSGN---GLGWFHISEHSGLVTTGSSGGL 540
+A G+ ++ + A D D GL A+ +RY + F + E SG V T + L
Sbjct: 949 PDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN--L 1006
Query: 541 DRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGT 600
+ E + L + A D G P +S + V L+ E P F+Q E V E A GT
Sbjct: 1007 NEEPTTIFKLVVVAFDDG-EPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGT 1065
Query: 601 ELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFY----- 655
+ ++ A N ++ +S+ + +F ++ ++G + LD E + Y
Sbjct: 1066 MVGVISAA----AINQSIVYSIVSGN-EEDTFGINNITGVIYVNGPLDYETRTSYVLRVQ 1120
Query: 656 --SLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSA 713
SL V+ +L P +S+ A++ + + D N++ PVF Y + E+ + + V A
Sbjct: 1121 ADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKA 1180
Query: 714 TDPDLGTNGTVKYSISAGD----RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
TD D G + Y + + F V +G+I T M ++ ++ Q++ATD
Sbjct: 1181 TDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDY 1240
Query: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+A V ++V++ D + S V + V
Sbjct: 1241 GKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1272
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 650 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 709
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 710 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 765
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 766 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 812
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 813 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 872
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 873 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 932
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 933 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 986
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 987 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 1042
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 1043 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1094
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1095 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1152
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1153 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1211
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1212 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1256
Score = 170 bits (430), Expect = 4e-41
Identities = 198/763 (25%), Positives = 324/763 (42%), Gaps = 81/763 (10%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 114 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 173
Query: 3005 VTAID----DKDFGLNSEVEYFI--------SNDNHLGKFKLDNDTGWISVASSLISDLN 3052
+ D D D G N ++EY I SND L TG I + L +
Sbjct: 174 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPTSNDTFEIPLML---TGNIVLRKRLNYEDK 230
Query: 3053 QNFFITVTAKDKG---NPPLSSQATVHITVTEENYHTPEFSQSHM------------SAT 3097
+F+ + A D+ N ++ T+ + V + + P F + A
Sbjct: 231 TRYFVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAA 290
Query: 3098 IPE---SHSIGSIVRT--VSARDRDAAMNGL-----IKYSISSGNEEG---IFAINSSTG 3144
IPE + I+ T + A D+D + I YSI G E F ++ T
Sbjct: 291 IPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTA 350
Query: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
L+L + ++ + QK ++ I A + + + ++D N+ SP F Y +L
Sbjct: 351 ELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 410
Query: 3205 ENAPSGTTV---------IHLNATDADSGTNAVIAYTVQSSDSDLFVID-------PNTG 3248
E+AP G T+ + + A D D + + LF+ D TG
Sbjct: 411 ESAPVGATISDSLNLTSPLRIVALDKDIEDVPPSGVPTKDPELHLFLNDYTSVFTVTQTG 470
Query: 3249 V---ITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
+ +T +D E +Q+Y ++ AF+ E VNIQ+ N+ P F Y
Sbjct: 471 ITRYLTLLQPVDREEQQTYTFSITAFDGVQESEP--VIVNIQVMDANDNTPTFPEISYDV 528
Query: 3306 EISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK 3365
+ G V ++ A D D G++GE+ Y I + + F INK TG I ++ ++
Sbjct: 529 YVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA-QGDFIINKTTGLITIAPGVEMIV 587
Query: 3366 EERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND--PPIFTLNIYSVQISEGVPIGTHV 3423
+L V A + TV + VL N+ PP F +YS++ISE + +G +
Sbjct: 588 GRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVL 647
Query: 3424 TFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAV 3483
+ A D + +Y I +G+ F+++ TG +T+ LDRE+ Y L + A
Sbjct: 648 LNLQATDREG----DSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITAS 703
Query: 3484 DSGTPSATGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQ 3541
D G P T +A++ + + D+NDN P+ + + + V +++TDPD N
Sbjct: 704 D-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGIN- 761
Query: 3542 GPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFY-LSVVTKDSGVPQMSSTGTV 3600
G Y S G + F +++ G + T +++RE + D+Y L VV D V ST T+
Sbjct: 762 GQVHY---SLGNFNNLFRITSNGSIYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTL 817
Query: 3601 HITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV 3643
I V+D +DN V NL G + ++ +D D+
Sbjct: 818 AIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDL 860
Score = 150 bits (379), Expect = 3e-35
Identities = 187/718 (26%), Positives = 299/718 (41%), Gaps = 101/718 (14%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 138 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 197
Query: 3130 SGNEE----GIFAINSS-TGILTLAKALDYELCQKHEMTISAIDGGW---VARTGYCSVT 3181
++ F I TG + L K L+YE ++ + I A D RT ++T
Sbjct: 198 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTTLT 257
Query: 3182 VNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD-- 3239
V+V+D +D P+FL P + P + ++ +Q+ D D
Sbjct: 258 VDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRN 317
Query: 3240 ------------------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPD 3275
F + P T ++ ++ + Q + L +KA
Sbjct: 318 IQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNG 377
Query: 3276 EERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRD 3326
+FA ++I++ N P F Y I E+AP G + + + A D+D
Sbjct: 378 HPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKD 437
Query: 3327 LGT---------DGEVHYLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLA 3375
+ D E+H +F N F + + Y++ + +DRE+++ + + A
Sbjct: 438 IEDVPPSGVPTKDPELH--LFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA 495
Query: 3376 KNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSI 3434
F ++ + + V VN+ V+DAND P F Y V + + G V ++A D+D
Sbjct: 496 --FDGVQ--ESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE- 550
Query: 3435 PSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSA 3494
S +Y I G + G F IN TG IT+ ++ Y L+V A D+ P+ ++
Sbjct: 551 GSNGEITYEILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNS 609
Query: 3495 SLLVTLEDINDNG------PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYL 3548
V +E + N P L S E+ E R G +++ LQ+TD +G Y
Sbjct: 610 ICTVYIEVLPPNNQSPPRFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYA 663
Query: 3549 LSTGPATSYFSLS-TAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQ 3607
+ G F+LS T G+L+ + +DRE D Y+ ++T G P +ST TV+I V D
Sbjct: 664 IENGDPQRVFNLSETTGILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDV 722
Query: 3608 NDN-----PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFS 3660
NDN P R + + V N F +G VK DPD + H SL +LF
Sbjct: 723 NDNAPVFDPYLPRNLSV-VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFR 776
Query: 3661 IP--GGTCDLNSQPRSTDGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
I G R ++L V++ DG HST+T I+V ++ NS
Sbjct: 777 ITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 834
>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
Length = 1915
Score = 332 bits (851), Expect = 6e-90
Identities = 310/1165 (26%), Positives = 514/1165 (44%), Gaps = 118/1165 (10%)
Query: 1692 TAAILDREQGACLY--LVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTV 1749
T +LDR+ ++ +V V I K EV I ++D NDN P F + TV
Sbjct: 99 TGRVLDRDPPMNIHSIVVQVQCINKKVG--TIIYHEVRIVVRDRNDNSPTFKHESYYATV 156
Query: 1750 EENIGDGSKIM-----QLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDR 1804
E G+ I A D D+G N + Y I DD R + L+
Sbjct: 157 NELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPDDPDR----------AQNLNE 206
Query: 1805 ERRSKYSLLVRADDGLQSSDMRIN-ITVSDVNDHTP-KFSRPVYSFDIPEDTIPGSLVAA 1862
R + +L V DG M + + V + D P + + PE+ P +
Sbjct: 207 RRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPP 266
Query: 1863 ILATDDDSGVNGE-----ITYIV---NEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYIL 1914
I A D D + I Y + +D F ++P T +L ++ + Q + L
Sbjct: 267 IQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDL 326
Query: 1915 TVRAEDGGGQFTTI--RVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVL-VFNVT-- 1969
++AE G ++ ILD N+ P F++ SY ++E+ PVG+T+ N+T
Sbjct: 327 VIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSP 386
Query: 1970 --------DADDGINSQLTYSIASGDSLGQFTVDKNGV---LKVLKALDRESQSFYNLVV 2018
D +D + +L + D FTV + G+ L +L+ +DRE Q Y +
Sbjct: 387 LRIVALDKDIEDTKDPELHLFL--NDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSI 444
Query: 2019 QVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY----IPENTPIDTVVFKAQA 2074
D Q + V+I ++D NDN PTF P+++Y + P D+V+ + A
Sbjct: 445 TAFDGVQE-----SEPVIVNIQVMDANDNTPTF--PEISYDVYVYTDMRPGDSVI-QLTA 496
Query: 2075 TDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSL 2134
D D G N I Y +L F I G + + ++ Y LTV A D P+
Sbjct: 497 VDADEGSNGEITYEILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAE 556
Query: 2135 SSSTEVVVMVLDINDNN---PIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRY 2191
++ V + + NN P F Q +Y +EI+E G ++ + A D + + Y
Sbjct: 557 RRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITY 613
Query: 2192 GIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLD 2251
I NG+ + F + TG +T+ K LDRE T Y L + A+D G T T+TV+IV+ D
Sbjct: 614 AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTD 672
Query: 2252 INDFVPVFELSPYSVNVPENLGTLPRT----ILQVVARDDDRGSNSKLSYVLFGGNEDNA 2307
+ND PVF+ PY +P NL + + QV A D D G N ++ Y L GN +N
Sbjct: 673 VNDNAPVFD--PY---LPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNL 725
Query: 2308 FTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASK 2367
F ++++G + L+RE ++ + L++ ATD T T+ + V D++DN P F +
Sbjct: 726 FRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 785
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQ--FTINPSTGQIITSALLDR 2425
Y + E+ P GT +L + A D D N RI + F ++P TG++ LD
Sbjct: 786 TYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDY 845
Query: 2426 ET----KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLP 2481
E + + T +V D P +T V V V D+ND PP F Y + +
Sbjct: 846 EAFPDQEASITFLVEAFDIYGTMPPGIAT-VTVIVKDMNDYPPVFSKRIYKGMVAPDAVK 904
Query: 2482 GSFVFAVTVTDADIG--PNSELHYSLSGRN----SEKFHIDPLRGAIMAAGPLNGASEVT 2535
G+ + V DAD P S + Y + + F ++ G ++ LN
Sbjct: 905 GTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTI 964
Query: 2536 FSVHVK--DGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTT----- 2588
F + V D G + S TV + ++ + P+ +E PVS L T
Sbjct: 965 FKLVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEY-----RPPPVSELATKGTMVG 1019
Query: 2589 ITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEA------- 2641
+ ++ + + Y I SGN +TF I+ +TG + ++ PLD+E YV+ ++A
Sbjct: 1020 VISAAAINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVL 1079
Query: 2642 RDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPN 2700
+ P S+ K+ I + D N++ P+F++ +I + E+ +L V A DKD+G
Sbjct: 1080 ANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNY 1139
Query: 2701 GQLDYEIVNGNM---ENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSV 2757
+ Y ++ + + F + TG I++ + S++ + ++D S
Sbjct: 1140 SVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKA 1199
Query: 2758 KVMINILDENDNAPRFSQIFSAHVP 2782
V+++++++ D Q+ ++VP
Sbjct: 1200 DVLVSVVNQLD-----MQVIVSNVP 1219
Score = 332 bits (851), Expect = 6e-90
Identities = 320/1144 (27%), Positives = 508/1144 (44%), Gaps = 100/1144 (8%)
Query: 338 EALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQ 397
E I + D NDN P K S YA+V+E VGT + T D+ A + +
Sbjct: 132 EVRIVVRDRNDNSPTFKHE-----SYYATVNELTPVGTTI--FTGFSGDNGATDIDD--- 181
Query: 398 ILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSS 457
G N Q + +Q N A L+ R + LTV V D P
Sbjct: 182 --GPNGQIEYVIQY----NPDDPDRAQNLNERRTTTTTLTVDVLDGDDLGP--------M 227
Query: 458 VASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNA-----NLRY 512
V+ N + P + + + EE P I A D D + + Y
Sbjct: 228 FLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILY 287
Query: 513 SIVSGNGLGW---FHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLV 569
SI+ G + FH+ H ++R+ + L I A HP ++A L
Sbjct: 288 SILVGTPEDYPRFFHM--HPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAGLH 345
Query: 570 VTLLDVNDEKPVFSQPEGYDVSVVENAPTG---------TELLMLRATDGDLGDNGTVRF 620
+ +LD N++ P F+ P Y ++E+AP G T L + A D D+ D
Sbjct: 346 IEILDENNQSPYFTMP-SYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPEL 404
Query: 621 SL-QEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSL 679
L T + ++ L+ + +DREEQ Y+ + A D +S +N+ +
Sbjct: 405 HLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFD--GVQESEPVIVNIQV 462
Query: 680 LDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVN 739
+D NDN+P F + Y ++ + G + ++A D D G+NG + Y I G + F +N
Sbjct: 463 MDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIIN 522
Query: 740 AQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTI---TVLDTQDNPPVFSQV 796
+G+I+ ++ Y L + A D +I T+ + +PP F Q+
Sbjct: 523 KTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQL 582
Query: 797 AYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDR 856
YS + E + +G + ++ A+ + +I+Y I GD + +F +++ TG LT +DR
Sbjct: 583 MYSLEISEAMRVGAVLLNLQATDRE-GDSITYAIENGDPQRVFNLSETTGILTLGKALDR 641
Query: 857 EEQSFYQLKVVASGGTVTGDT--MVNITVKDLNDNSPHFLQAI-ESVNVVENWQAGHSIF 913
E Y L + AS G G + VNI V D+NDN+P F + +++VVE +A +
Sbjct: 642 ESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEE-EANAFVG 700
Query: 914 QAKAVDPDEGVNGMVLYSLKQNPKNLFAINEKNGTISLLGPLDVHAGS-YQIEILASDMG 972
Q KA DPD G+NG V YSL N NLF I NG+I L+ Y++ ++A+D
Sbjct: 701 QVKATDPDAGINGQVHYSL-GNFNNLFRIT-SNGSIYTAVKLNREVRDYYELVVVATDGA 758
Query: 973 VPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIA 1032
V S++ L + V D++DNSPVF +Y V + E+ P + +++A D D GAN ++
Sbjct: 759 VHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VS 816
Query: 1033 YTIAEGNTGDAFGIFP-DGQLYIKSELDREL----QDRYVLMVVASDRAVEPLSATVNVT 1087
Y I F + P G+L + LD E + +V A D VT
Sbjct: 817 YRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVT 876
Query: 1088 VILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG--PNGEVRYSFEMVQ-- 1143
VI++D+ND P+F+ Y + G+ + V A D D P VRY + VQ
Sbjct: 877 VIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFP 936
Query: 1144 ---PDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYM 1200
FE+ SG + + E T +F V+A D G P + ATV + +
Sbjct: 937 YPASIFEVEEDSGRVITRVNLNEEP------TTIFKLVVVAFDDGEP-VMSSSATVKILV 989
Query: 1201 KDINDNAPKFLKDFYQ-ATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFA 1259
+ P+F ++ Y+ +SE A T V +SA+ +++ I YSI+ GNEE F
Sbjct: 990 LHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAAAINQS----IVYSIVSGNEEDTFG 1044
Query: 1260 IDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPL--------NSTCTLNIDILDENDN 1311
I++ +G + + G LDYE +Y L +QA DS + L ++T + I+I DEN++
Sbjct: 1045 INNITGVIYVNGPLDYETRTSYVLRVQA-DSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1103
Query: 1312 TPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI---TGTNNHGTFSISPN 1368
P F K V E+ R+ V V ATD D+G+ + + Y + F +
Sbjct: 1104 PPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETY 1163
Query: 1369 TGSIFLAKKLDFETQSLYKLNITAKD---QGRPPRSSTMSVVIHVRDFNDNPPSFPPGDI 1425
TG I A +S +K + A D +G ++ + V++ D + PP +
Sbjct: 1164 TGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLV 1223
Query: 1426 FKSI 1429
K I
Sbjct: 1224 EKKI 1227
Score = 323 bits (828), Expect = 3e-87
Identities = 294/1103 (26%), Positives = 489/1103 (44%), Gaps = 113/1103 (10%)
Query: 463 IFVNDINDHPPVFSQQVYRVNLSEEAPPGSYV-SGIS----ATDGDSGLNANLRYSIVSG 517
I V D ND+ P F + Y ++E P G+ + +G S ATD D G N + Y I
Sbjct: 135 IVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYN 194
Query: 518 NGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVND 577
D + A N++ R + + L V +LD +D
Sbjct: 195 PD---------------------DPDRAQ----NLNER------RTTTTTLTVDVLDGDD 223
Query: 578 EKPVF-----------SQPEGYDVSVVE-NAPTGTELLM----LRATDGDLG-----DNG 616
P+F +P Y ++ E P ++ ++A D D D
Sbjct: 224 LGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRP 283
Query: 617 TVRFSLQEA--ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMAR 674
+ +S+ E R F + P + LS + ++R+ + L++ A P + A
Sbjct: 284 GILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAG 343
Query: 675 INVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITT---------VSATDPDLGTNGTVK 725
+++ +LD N+ SP F Y +I E+ P G+ I+ + A D D+ +
Sbjct: 344 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE 403
Query: 726 YSISAGDRSRFQVNAQSGV---ISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTIT 782
+ D + Q+G+ ++ +DREE+ Y I A DG +Q IV I
Sbjct: 404 LHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEPVIVNIQ 461
Query: 783 VLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSN--ISYLITTGDQKGMFA 840
V+D DN P F +++Y V+ ++ G V ++A D SN I+Y I G Q G F
Sbjct: 462 VMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQ-GDFI 520
Query: 841 INQVTGQLTTANVIDREEQSFYQLKVVASGGTVTGDTMVNITVKDL------NDNSPHFL 894
IN+ TG +T A ++ Y L V A+ + +I + N + P F
Sbjct: 521 INKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFP 580
Query: 895 QAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQ-NPKNLFAINEKNGTISLLG 953
Q + S+ + E + G + +A D + + Y+++ +P+ +F ++E G ++L
Sbjct: 581 QLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGK 637
Query: 954 PLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNS 1013
LD + I I+ + G P +S+ + + V DVNDN+PVFD E N+
Sbjct: 638 ALDRESTDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANA 697
Query: 1014 RFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMVVAS 1073
+V+A+D D+G NG++ Y++ GN + F I +G +Y +L+RE++D Y L+VVA+
Sbjct: 698 FVGQVKATDPDAGINGQVHYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVAT 755
Query: 1074 DRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNG 1133
D AV P +T+ + + + D++DN P+F ++ YT EE AG+ + ++ A D D G N
Sbjct: 756 DGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANV 815
Query: 1134 EVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQ 1193
R V+ F LH +GE++ D E+ + + F +P +
Sbjct: 816 SYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGI--- 872
Query: 1194 ATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGN 1253
ATV V +KD+ND P F K Y+ ++ A T + V A D D GL +
Sbjct: 873 ATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP--PGLPASRVRYRV 930
Query: 1254 EERQ-------FAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDIL 1306
++ Q F ++ SG+V L+ E T + LV+ A D G ++S+ T+ I +L
Sbjct: 931 DDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVL 990
Query: 1307 DENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSIS 1366
+ + V E G +V ++A + N + YSI N TF I+
Sbjct: 991 HPGEIPRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGIN 1046
Query: 1367 PNTGSIFLAKKLDFETQSLYKLNITA-------KDQGRPPRSSTMSVVIHVRDFNDNPPS 1419
TG I++ LD+ET++ Y L + A + P +S+T V I ++D N++PP
Sbjct: 1047 NITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPV 1106
Query: 1420 FPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSY-TIIQQMPRGNH-FTIDEVKGT 1477
F + E+ + TSV+ V A D D ++Y II + G F ++ G
Sbjct: 1107 FQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGL 1166
Query: 1478 IYTNAEIDREFANLFELTVKAND 1500
I T + F+ V A D
Sbjct: 1167 IKTAMLFHNMRRSYFKFQVIATD 1189
Score = 289 bits (740), Expect = 4e-77
Identities = 307/1131 (27%), Positives = 495/1131 (43%), Gaps = 140/1131 (12%)
Query: 120 EVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRG 179
EVR++VRD NDN+P F S T E + G + T D G+ +D
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIF--TGFSGDNGATDIDD-------- 181
Query: 180 NEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVT 239
G+ I NP +L + T L V+V D G+ +L V
Sbjct: 182 GPNGQIEYVIQYNPDDPDRAQNL------NERRTTTTTLTVDVLD-GDDLGPMFLPC-VL 233
Query: 240 VQDINDNPPVFGSSHYQAGVPE-------DAVVGSSVLQVAAADADEGTNAD---IRYRL 289
V + D P+ YQA +PE + ++ + +Q D + +D I Y +
Sbjct: 234 VPNTRDCRPLT----YQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSI 289
Query: 290 QDEGTP------FQMDPETGLITVREPLDFEARRQYSLTVQA-MDRGVPSLTGRAEALIQ 342
GTP F M P T +++ EP++ + +++ L ++A D G P L A I+
Sbjct: 290 L-VGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP-LPAFAGLHIE 347
Query: 343 LLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGN 402
+LD N+ P YF S + E+A VG + S + N ++I+ +
Sbjct: 348 ILDENNQSP-----YFTMPSYQGYILESAPVGATI---------SDSLNLTSPLRIVALD 393
Query: 403 EQRHFEVQSSKVPNLSL-------------------IKVASALDRERIPSYNLTVSVSDN 443
+ +++ +K P L L + + +DRE +Y +++ D
Sbjct: 394 K----DIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG 449
Query: 444 YGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGD 503
S + I V D ND+ P F + Y V + + PG V ++A D D
Sbjct: 450 V---------QESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDAD 500
Query: 504 SGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQG--VHP 561
G N + Y I+ G G F I++ +GL+T + G++ + L + A D
Sbjct: 501 EGSNGEITYEILVG-AQGDFIINKTTGLITI--APGVEMIVGRTYALTVQAADNAPPAER 557
Query: 562 KVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFS 621
+ S + + +L N++ P Y + + E G LL L+ATD + GD ++ ++
Sbjct: 558 RNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE-GD--SITYA 614
Query: 622 LQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
++ + +R F L +G L+ +LDRE Y L++ A+D G P +S A +N+ + D
Sbjct: 615 IENGD-PQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTD 672
Query: 682 INDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQ 741
+NDN+PVF P E +++ V ATDPD G NG V YS+ G+ +
Sbjct: 673 VNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITS 730
Query: 742 SGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFV 801
+G I T + L+RE + Y+L +VATDG + + I VLD DN PVF+ Y+ +
Sbjct: 731 NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVL 790
Query: 802 VFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVI------D 855
V EN+ G + + A +DL +N+SY I + + K FA++ TG+L+ + D
Sbjct: 791 VEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPD 850
Query: 856 REEQSFYQLKVVASGGTV-TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSI-- 912
+E + ++ GT+ G V + VKD+ND P F + I V + G I
Sbjct: 851 QEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITT 910
Query: 913 FQAKAVDPDEGVNGMVLYSLKQ----NPKNLFAINEKNGTISLLGPLDVHAGS-YQIEIL 967
A+ DP V Y + P ++F + E +G + L+ + +++ ++
Sbjct: 911 VYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVV 970
Query: 968 ASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYE-VTLSESEPVNSRFFKVQASDKDSG 1026
A D G P +SSS + + V + P F Q Y +SE + + A +
Sbjct: 971 AFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA----AA 1025
Query: 1027 ANGEIAYTIAEGNTGDAFGIFP-DGQLYIKSELDRELQDRYVLM-------VVASDRAVE 1078
N I Y+I GN D FGI G +Y+ LD E + YVL VV ++ V
Sbjct: 1026 INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVP 1085
Query: 1079 PLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYS 1138
S T V + ++D N++ P+F Y E+ R + V +V A DKD G + Y
Sbjct: 1086 SKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYR 1145
Query: 1139 FEMVQP------DFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATD 1183
++ P F + +G I F MRR + F F VIATD
Sbjct: 1146 L-IIPPIKEGKEGFVVETYTGLIKTAMLFHN---MRR---SYFKFQVIATD 1189
Score = 287 bits (734), Expect = 2e-76
Identities = 303/1110 (27%), Positives = 481/1110 (43%), Gaps = 117/1110 (10%)
Query: 937 KNLFAINEKNGTISLLGPLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVF 996
K + +N + P+++H+ Q++ + +G + + V D NDNSP F
Sbjct: 91 KQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHE---VRIVVRDRNDNSPTF 147
Query: 997 DQLSYEVTLSESEPVNSRFF-----KVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ 1051
SY T++E PV + F A+D D G NG+I Y I + N D PD
Sbjct: 148 KHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI-QYNPDD-----PDR- 200
Query: 1052 LYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPL-FNSTNYTFYFE 1110
L+ L V D + L V++ + D RPL + +
Sbjct: 201 ---AQNLNERRTTTTTLTVDVLDG--DDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTP 255
Query: 1111 EEQRAGSFVGKVSAVDKD--FGPNGE---VRYSFEMVQPD-----FELHAISGEITNTHQ 1160
EE + A+D+D P + + YS + P+ F +H + E++
Sbjct: 256 EELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEP 315
Query: 1161 FDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATIS 1220
+R+ + F VI +Q PL A +H+ + D N+ +P F YQ I
Sbjct: 316 VNRDFHQK------FDL-VIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYIL 368
Query: 1221 ESA---------ANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDST--SGQVTL 1269
ESA NLT LR+ A D D + + + F + T + +TL
Sbjct: 369 ESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTL 428
Query: 1270 IGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMR 1329
+ +D E Y+ I A D + + +NI ++D NDNTP+FP+ + V V +MR
Sbjct: 429 LQPVDREEQQTYTFSITAFDG--VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMR 486
Query: 1330 IGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLN 1389
G+ V +TA D+D G N ++ Y I G F I+ TG I +A ++ Y L
Sbjct: 487 PGDSVIQLTAVDADEGSNGEITYEIL-VGAQGDFIINKTTGLITIAPGVEMIVGRTYALT 545
Query: 1390 ITAKDQGRPP--RSSTMSVVIHV-RDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHD 1446
+ A D P R+S +V I V N +PP FP I E + +G ++++ A D
Sbjct: 546 VQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD 605
Query: 1447 PDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIE 1506
+ D ++Y I P+ F + E G + +DRE + + L + A+D P
Sbjct: 606 REGD---SITYAIENGDPQ-RVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG 660
Query: 1507 TRRYALKNVTILVTDLNDNVPMF---ISQNALAADPSAVIGSVLTTIMAADPDEGANGEI 1563
T + V I+VTD+NDN P+F + +N + A + + + A DPD G NG++
Sbjct: 661 T---STATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEA--NAFVGQVKATDPDAGINGQV 715
Query: 1564 EYEIINGDTDTFIVDRYSGDLRVASALVPS-QLIYNLIVSATDLGPERRKSTTELTIILQ 1622
Y + G+ + +G + A L + Y L+V ATD R ST L I +
Sbjct: 716 HYSL--GNFNNLFRITSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVL 773
Query: 1623 GLD--GPVFTQPKYITILKEGEPIGTNVISIEAAS-PRGSEAPVEYYIVSVRCEEKTVGR 1679
+D PVFT Y +++E P GT ++ IEA G+ VS R V
Sbjct: 774 DIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN-------VSYRIRSPEVKH 826
Query: 1680 LFTIGRHTGIIQTAAILDRE-----QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDIN 1734
F + TG + LD E + + +LV+ + I T P A V + ++D+N
Sbjct: 827 FFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDI-YGTMPPGI--ATVTVIVKDMN 883
Query: 1735 DNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADD--------S 1786
D PPVF + V + G+ I + A DAD L + DD
Sbjct: 884 DYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD--PPGLPASRVRYRVDDVQFPYPASI 941
Query: 1787 FRIDPESGDLIATRRLDRERRSKYSLLVRA-DDG--LQSSDMRINITVSDVNDHTPKFSR 1843
F ++ +SG +I L+ E + + L+V A DDG + SS + I V + P+F++
Sbjct: 942 FEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQ 1000
Query: 1844 PVY-SFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTR 1902
Y + E G++V I A + +N I Y + +E+ F +N ITGV +
Sbjct: 1001 EEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGINNITGVIYVNG 1056
Query: 1903 LLDYEVQQYYILTVRAED---------GGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSL 1953
LDYE + Y+L V+A+ + T +VY I D N++PP+F Y +
Sbjct: 1057 PLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGV 1116
Query: 1954 MENLPVGSTVLVFNVTDADDGINSQLTYSI 1983
E+ + ++VL TD D G S + Y +
Sbjct: 1117 SEDARMFTSVLRVKATDKDTGNYSVMAYRL 1146
Score = 283 bits (724), Expect = 3e-75
Identities = 267/925 (28%), Positives = 409/925 (44%), Gaps = 83/925 (8%)
Query: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
+ + + D N+ +P F PS E + G + S + +D + +
Sbjct: 344 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD-KDIEDTKDP 402
Query: 181 EAGRFRLD----ITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVED---KGEPKRRGY 233
E F D T+ +G +L L+ +DRE Y + D + EP
Sbjct: 403 ELHLFLNDYTSVFTVTQTGITRYLTLLQP--VDREEQQTYTFSITAFDGVQESEP----- 455
Query: 234 LQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYR-LQDE 292
+ VN+ V D NDN P F Y V D G SV+Q+ A DADEG+N +I Y L
Sbjct: 456 VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGA 515
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPS--LTGRAEALIQLLDVNDND 350
F ++ TGLIT+ ++ R Y+LTVQA D P+ I++L N+
Sbjct: 516 QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQS 575
Query: 351 PVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQ 410
P FP + E +VG V+ L TD + +I+ I G+ QR F +
Sbjct: 576 P----PRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITYAIENGDPQRVFNLS 627
Query: 411 SSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIND 470
+ ++ + ALDRE Y L ++ SD G P G +S A++ I V D+ND
Sbjct: 628 ET----TGILTLGKALDRESTDRYILIITASD--GRPDG------TSTATVNIVVTDVND 675
Query: 471 HPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSG 530
+ PVF + R E ++V + ATD D+G+N + YS+ + N L F I+ +
Sbjct: 676 NAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNL--FRITSNGS 733
Query: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
+ T L+RE+ L + A D VHP+ S L + +LD++D PVF+ Y V
Sbjct: 734 IYTAVK---LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN-STYTV 789
Query: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
V EN P GT +L + A D DLG N + R E + F L P +G LS + SLD E
Sbjct: 790 LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEV---KHFFALHPFTGELSLLRSLDYE 846
Query: 651 ----EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGS 706
++A + LV A D+ +A + V + D+ND PVF Y + + G+
Sbjct: 847 AFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGT 906
Query: 707 YITTVSATDPDLG--TNGTVKYSIS----AGDRSRFQVNAQSGVISTRMALDREEKTAYQ 760
ITTV A D D V+Y + S F+V SG + TR+ L+ E T ++
Sbjct: 907 PITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFK 966
Query: 761 LQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTM 820
L +VA D G + A V I VL + P + V E G VG +SA+
Sbjct: 967 LVVVAFDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA- 1025
Query: 821 DLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGGTV------- 873
+N +I Y I +G+++ F IN +TG + +D E ++ Y L+V A V
Sbjct: 1026 -INQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRV 1084
Query: 874 ---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLY 930
+ V I ++D N++ P F + V E+ + S+ + KA D D G ++ Y
Sbjct: 1085 PSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAY 1144
Query: 931 SLKQNP----KNLFAINEKNGTISLLGPL-DVHAGSYQIEILASDMGVPQLSSSVILTVY 985
L P K F + G I ++ ++ +++A+D LS + V
Sbjct: 1145 RLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV- 1203
Query: 986 VHDVNDNSPVFDQLSYEVTLSESEP 1010
V +QL +V +S P
Sbjct: 1204 --------SVVNQLDMQVIVSNVPP 1220
Score = 278 bits (711), Expect = 1e-73
Identities = 261/971 (26%), Positives = 431/971 (44%), Gaps = 78/971 (8%)
Query: 2690 VSAMDKDSGPNGQLD-----YEIVNGNMENS---FSINHATGEIRSVRPLDREKVSHYVL 2741
+ A+D+D D Y I+ G E+ F ++ T E+ + P++R+ + L
Sbjct: 267 IQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDL 326
Query: 2742 TIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVT-------- 2792
IK+ + I ILDEN+ +P F+ + ++ E++P+G T++
Sbjct: 327 VIKAEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSP 386
Query: 2793 -RVTTSDEDIGINAISRYSIM--DASLPFTINPS--TGDIVISRPLNREDTDRYRIRVSA 2847
R+ D+DI + D + FT+ + T + + +P++RE+ Y ++A
Sbjct: 387 LRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA 446
Query: 2848 HDSGW-TVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQ 2906
D + V I V D NDN P F SY + G V Q+ A D DEGSNG+
Sbjct: 447 FDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGE 506
Query: 2907 VFY--FIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLI 2964
+ Y + +Q ++ IN TTG I G + ++ V ++D P+
Sbjct: 507 ITYEILVGAQGDFI-INKTTGLI--------TIAPGVEMIVGRTYALTVQAADNAPPAER 557
Query: 2965 SETTVTINIV---DSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY 3021
+ T+ I +N + P+F + Y +++ ++VG L+ + A D + + Y
Sbjct: 558 RNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE----GDSITY 613
Query: 3022 FISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTE 3081
I N + F L TG +++ +L + + + +TA D G P +S ATV+I VT+
Sbjct: 614 AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTD 672
Query: 3082 ENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINS 3141
N + P F + V V A D DA +NG + YS+ GN +F I S
Sbjct: 673 VNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRITS 730
Query: 3142 STGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFP 3201
+ I T K L+ E+ +E+ + A DG R ++ + V+D++DNSPVF + Y
Sbjct: 731 NGSIYTAVK-LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTV 789
Query: 3202 TVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSD-SDLFVIDPNTGVITTQGFLDFET 3260
V EN P+GTT++ + A D D G N ++Y ++S + F + P TG ++ LD+E
Sbjct: 790 LVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEA 847
Query: 3261 ----KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTI 3316
+ S V+AF++ ATV + +K N+Y P F ++Y ++ A KGT
Sbjct: 848 FPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTP 907
Query: 3317 VGEVFASDRDLG--TDGEVHYLIFGNS---RKKGFQINKKTGQIYVSGILDREKEERVSL 3371
+ V+A D D V Y + F++ + +G++ L+ E L
Sbjct: 908 ITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKL 967
Query: 3372 KVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIY-SVQISEGVPIGTHVTFVSAFD 3430
V+A F TV + VL + P FT Y +SE GT V +SA
Sbjct: 968 VVVA--FDDGEPVMSSSATVKILVLHPGEIPRFTQEEYRPPPVSELATKGTMVGVISAAA 1025
Query: 3431 SDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIY-------NLSVLAV 3483
+ Y I SGNE F IN TG I V LD ET Y +L V+
Sbjct: 1026 IN-----QSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLA 1080
Query: 3484 DSGTPSATGSASLLVTLEDINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLPPNQ 3541
+ PS + +A + + ++D N++ P+ G V E+ R T V+ +++TD D N
Sbjct: 1081 NLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKD-TGNY 1139
Query: 3542 GPFTYYLL--STGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTG 3598
Y L+ F + T G++ T + + F V+ D +S
Sbjct: 1140 SVMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKA 1199
Query: 3599 TVHITVIDQND 3609
V ++V++Q D
Sbjct: 1200 DVLVSVVNQLD 1210
Score = 254 bits (649), Expect = 1e-66
Identities = 275/1034 (26%), Positives = 459/1034 (44%), Gaps = 133/1034 (12%)
Query: 2652 YEKLDITVLDVNDNAPIFKEDPFISEILENLSP--RKILTV-----SAMDKDSGPNGQLD 2704
Y ++ I V D NDN+P FK + + + + E L+P I T A D D GPNGQ++
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIE 188
Query: 2705 YEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINIL 2764
Y I P D ++ + + ++T+ + +++L
Sbjct: 189 YVI-------------------QYNPDDPDRAQNL----------NERRTTTTTLTVDVL 219
Query: 2765 DENDNAPRFSQI-------------FSAHVPE-NSPLGYTVTRVTTS----DEDIGINAI 2806
D +D P F + A +PE +P VT D+D I
Sbjct: 220 DGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPP 279
Query: 2807 SR-----YSIM-----DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAH-DSGWTVS 2855
S YSI+ D F ++P T ++ + P+NR+ ++ + + A D+G +
Sbjct: 280 SDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLP 339
Query: 2856 T--DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVT---------QVFATDPD--EG 2902
+ I + D N+ +P F+ SY E +G+ ++ ++ A D D +
Sbjct: 340 AFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDT 399
Query: 2903 SNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPS 2962
+ ++ F+ + F + T + + Q V ++F +T+ D + S
Sbjct: 400 KDPELHLFLNDYTSVFTVTQTG---ITRYLTLLQPV---DREEQQTYTFSITAFDGVQES 453
Query: 2963 LISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYF 3022
V I ++D+NDN P F + Y V +++ G +I++TA+D D G N E+ Y
Sbjct: 454 --EPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVD-ADEGSNGEITYE 510
Query: 3023 ISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPP--LSSQATVHITVT 3080
I G F ++ TG I++A + + + + +TV A D P +S TV+I V
Sbjct: 511 ILVGAQ-GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVL 569
Query: 3081 EENYHTP-EFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAI 3139
N +P F Q S I E+ +G+++ + A DR+ I Y+I +G+ + +F +
Sbjct: 570 PPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS---ITYAIENGDPQRVFNL 626
Query: 3140 NSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVI--DVNDNSPVFLSD 3197
+ +TGILTL KALD E ++ + I+A DG G + TVN++ DVNDN+PVF D
Sbjct: 627 SETTGILTLGKALDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVF--D 681
Query: 3198 DYFPTVLE--NAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGF 3255
Y P L + V + ATD D+G N + Y++ + ++LF I N G I T
Sbjct: 682 PYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL-GNFNNLFRITSN-GSIYTAVK 739
Query: 3256 LDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGT 3315
L+ E + Y L V A + R S T+ I++ ++ P F + Y + E P GT
Sbjct: 740 LNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGT 799
Query: 3316 IVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREK--EERVSLKV 3373
+ ++ A D DLG + V Y I K F ++ TG++ + LD E ++ S+
Sbjct: 800 TILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITF 857
Query: 3374 LAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSD 3432
L + F TV V V D ND PP+F+ IY ++ GT +T V A D+D
Sbjct: 858 LVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDAD 917
Query: 3433 --SIPSWSRFSYFIGSGN---ENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGT 3487
+P+ SR Y + F + +G++ L+ E I+ L V+A D G
Sbjct: 918 PPGLPA-SRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGE 976
Query: 3488 PSATGSASLLVTLEDINDNGPMLTVSEGE---VMENKRPGTLVMTLQSTDPDLPPNQGPF 3544
P + SA++ + + + P T E V E GT+V + + NQ
Sbjct: 977 PVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMVGVISAA----AINQS-I 1030
Query: 3545 TYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYL-------SVVTKDSGVPQMSST 3597
Y ++S ++ + GV+ +D E + L VV + VP S+T
Sbjct: 1031 VYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNT 1090
Query: 3598 GTVHITVIDQNDNP 3611
V+I + D+N++P
Sbjct: 1091 AKVYIEIQDENNHP 1104
Score = 240 bits (613), Expect = 2e-62
Identities = 291/1148 (25%), Positives = 478/1148 (41%), Gaps = 152/1148 (13%)
Query: 1196 VHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRV-----SASDVDEGNNGLIHYSII 1250
V + ++D NDN+P F + Y AT++E T + A+D+D+G NG I Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 1251 KGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDEND 1310
++ A + + T T TL +D+LD +D
Sbjct: 193 YNPDDPDRAQNLNERRTT-----------------------------TTTLTVDVLDGDD 223
Query: 1311 NTPSFPKSTL-----------FVDVLENMRIGELVSSVTAT------DSDSG-----DNA 1348
P F L + + +R E ++ + T D D D
Sbjct: 224 LGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRP 283
Query: 1349 DLYYSI---TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMS 1405
+ YSI T + F + P T + L + ++ + + L I A+ P +
Sbjct: 284 GILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAG 343
Query: 1406 VVIHVRDFNDNPPSFPPGDIFKSIVENIPIG---------TSVISVTAHDPDADINGQLS 1456
+ I + D N+ P F I+E+ P+G TS + + A D D +
Sbjct: 344 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE 403
Query: 1457 YTIIQQMPRGNHFTIDEVKGTIYTNA--EIDREFANLFELTVKANDQAVPIETRRYALKN 1514
+ + FT+ + T Y +DRE + ++ A D E
Sbjct: 404 LHLFLN-DYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEP-----VI 457
Query: 1515 VTILVTDLNDNVPMF--ISQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT 1572
V I V D NDN P F IS + SV+ + A D DEG+NGEI YEI+ G
Sbjct: 458 VNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQ-LTAVDADEGSNGEITYEILVGAQ 516
Query: 1573 DTFIVDRYSGDLRVASAL-VPSQLIYNLIVSATDLGPERRKSTTELTIILQGL-----DG 1626
FI+++ +G + +A + + Y L V A D P + + T+ ++ L
Sbjct: 517 GDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 576
Query: 1627 PVFTQPKYITILKEGEPIGTNVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRH 1686
P F Q Y + E +G +++++A G ++ E R+F +
Sbjct: 577 PRFPQLMYSLEISEAMRVGAVLLNLQATDREGDS-------ITYAIENGDPQRVFNLSET 629
Query: 1687 TGIIQTAAILDREQGACLYLVDVYAIEKSTAFP-RTQRAEVEITLQDINDNPPVF-PTDM 1744
TGI+ LDRE L+ I S P T A V I + D+NDN PVF P
Sbjct: 630 TGILTLGKALDRESTDRYILI----ITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLP 685
Query: 1745 LDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDR 1804
+L+V E + + + Q+ A D D G N V Y+ + ++ FRI +G + +L+R
Sbjct: 686 RNLSVVEEEAN-AFVGQVKATDPDAGINGQVHYS-LGNFNNLFRI-TSNGSIYTAVKLNR 742
Query: 1805 ERRSKYSLLVRADDGL---QSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVA 1861
E R Y L+V A DG + S + + I V D++D++P F+ Y+ + E+ G+ +
Sbjct: 743 EVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTIL 802
Query: 1862 AILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEV----QQYYILTVR 1917
I A D D G N ++Y + + F L+P TG +L R LDYE + V
Sbjct: 803 QIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVE 860
Query: 1918 AEDGGGQ----FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDAD- 1972
A D G T+ V + D+ND PP+FS Y + + G+ + DAD
Sbjct: 861 AFDIYGTMPPGIATVTVI--VKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADP 918
Query: 1973 DGI-NSQLTYSIASGD-----SLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQI 2026
G+ S++ Y + S+ + D V+ + L+ E + + LVV D +
Sbjct: 919 PGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVN-LNEEPTTIFKLVVVAFDDGEP 977
Query: 2027 PASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGP--NSY 2084
S S+A V I++L + P F + Y P P+ + K S N
Sbjct: 978 VMS---SSATVKILVLHPGE-IPRFTQEE--YRP--PPVSELATKGTMVGVISAAAINQS 1029
Query: 2085 IEYTLLNPLGNK---FSIGTIDGEVRLTGELDREEVSNY-------TLTVVATDKGQPSL 2134
I Y++++ GN+ F I I G + + G LD E ++Y +L VV + PS
Sbjct: 1030 IVYSIVS--GNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSK 1087
Query: 2135 SSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIV 2194
S++ +V + + D N++ P+F + Y ++E+ T +++V A D D G + Y ++
Sbjct: 1088 SNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLI 1147
Query: 2195 ---NGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATD---RGSTPRTDTSTVSIV 2248
+ F +++ TG I A + + V ATD +G + + D +
Sbjct: 1148 IPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1207
Query: 2249 LLDINDFV 2256
LD+ V
Sbjct: 1208 QLDMQVIV 1215
Score = 237 bits (604), Expect = 2e-61
Identities = 279/1065 (26%), Positives = 448/1065 (42%), Gaps = 94/1065 (8%)
Query: 233 YLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVL-----QVAAADADEGTNADIRY 287
Y +V + V+D NDN P F Y A V E VG+++ A D D+G N I Y
Sbjct: 130 YHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEY 189
Query: 288 RLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVN 347
+Q DP+ + L+ +LTV +D L + + +
Sbjct: 190 VIQYNPD----DPDRA-----QNLNERRTTTTTLTVDVLDG--DDLGPMFLPCVLVPNTR 238
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ--- 404
D P+ P ++ + A+ + P+ I IL G +
Sbjct: 239 DCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYP 298
Query: 405 RHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIF 464
R F + P + + + ++R+ ++L + + G P A A L I
Sbjct: 299 RFFHMH----PRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPA-------FAGLHIE 347
Query: 465 VNDINDHPPVFSQQVYRVNLSEEAPPGSYVSG---------ISATDGDSGLNANLRYSIV 515
+ D N+ P F+ Y+ + E AP G+ +S I A D D + +
Sbjct: 348 ILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLF 407
Query: 516 SGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARD--QGVHPKVSYAQLVVTLL 573
+ F +++ +DRE +I+A D Q P + + + ++
Sbjct: 408 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVI----VNIQVM 463
Query: 574 DVNDEKPVFSQPE-GYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFS-LQEAETDRRS 631
D ND P F PE YDV V + G ++ L A D D G NG + + L A+ D
Sbjct: 464 DANDNTPTF--PEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGD--- 518
Query: 632 FRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQ--SSMARINVSLLDINDNSPVF 689
F ++ +G ++ ++ Y+L V A D P + +S+ + + +L N+ SP
Sbjct: 519 FIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPR 578
Query: 690 YP-VQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSR-FQVNAQSGVIST 747
+P + Y I E G+ + + ATD + ++ Y+I GD R F ++ +G+++
Sbjct: 579 FPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTL 635
Query: 748 RMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFS-QVAYSFVVFENV 806
ALDRE Y L I A+D G + A V I V D DN PVF + + V E
Sbjct: 636 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEE 694
Query: 807 ALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKV 866
A + VG V A+ D N + G+ +F I G + TA ++RE + +Y+L V
Sbjct: 695 ANAF-VGQVKATDPDAGINGQVHYSLGNFNNLFRITS-NGSIYTAVKLNREVRDYYELVV 752
Query: 867 VASGGTV---TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEG 923
VA+ G V + I V D++DNSP F + +V V EN AG +I Q +A D D G
Sbjct: 753 VATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLG 812
Query: 924 VNGMVLYSLKQ-NPKNLFAINEKNGTISLLGPLDVHA-----GSYQIEILASDMGVPQLS 977
N V Y ++ K+ FA++ G +SLL LD A S + A D+
Sbjct: 813 AN--VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP 870
Query: 978 SSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGA--NGEIAYTI 1035
+TV V D+ND PVF + Y+ ++ + V A D D + Y +
Sbjct: 871 GIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRV 930
Query: 1036 AEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILE 1091
+ IF G++ + L+ E + L+VVA D +S++ V +++
Sbjct: 931 DDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVL 990
Query: 1092 DVNDNRPLFNSTNY-TFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM--VQPDFEL 1148
+ P F Y E G+ VG +SA N + YS + F +
Sbjct: 991 HPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA----AINQSIVYSIVSGNEEDTFGI 1045
Query: 1149 HAISGEITNTHQFD---RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDIND 1205
+ I+G I D R S + R S V+ + +P + A V++ ++D N+
Sbjct: 1046 NNITGVIYVNGPLDYETRTSYVLR--VQADSLEVVLANLRVPSK-SNTAKVYIEIQDENN 1102
Query: 1206 NAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSII 1250
+ P F K FY +SE A T VLRV A+D D GN ++ Y +I
Sbjct: 1103 HPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLI 1147
Score = 218 bits (554), Expect = 2e-55
Identities = 229/864 (26%), Positives = 362/864 (41%), Gaps = 116/864 (13%)
Query: 2806 ISRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDI 2865
+ + +MD STG ++ P + +++ G + +V I V D
Sbjct: 81 VDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCINKKVGTIIYHEVRIVVRDR 140
Query: 2866 NDNAPRFSRTSYYLDCPELTEIGSKVTQVF-----ATDPDEGSNGQVFYFIKSQSEYFRI 2920
NDN+P F SYY ELT +G+ + F ATD D+G NGQ+ Y I+ +
Sbjct: 141 NDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPD---- 196
Query: 2921 NATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
+ N+N R + TT+T++++D +D
Sbjct: 197 ----------------DPDRAQNLNERR---------------TTTTTLTVDVLDGDDLG 225
Query: 2981 PQFLK-------------------SKYFTPVTKNVKVGTKLIRVTAID-DKDFGLNSE-- 3018
P FL + TP N + T I+ AID D++ S+
Sbjct: 226 PMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQ--AIDQDRNIQPPSDRP 283
Query: 3019 -VEYFI---SNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQAT 3074
+ Y I + +++ F + T +S+ + D +Q F + + A+ PL + A
Sbjct: 284 GILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAG 343
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVR---------TVSARDRDAAMNGLIK 3125
+HI + +EN +P F+ I ES +G+ + + A D+D +
Sbjct: 344 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE 403
Query: 3126 YSISSGNEEGIFAINSS--TGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVN 3183
+ + +F + + T LTL + +D E Q + +I+A DG V + V +
Sbjct: 404 LHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEPVIVNIQ 461
Query: 3184 VIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVI 3243
V+D NDN+P F Y V + G +VI L A DAD G+N I Y + F+I
Sbjct: 462 VMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFII 521
Query: 3244 DPNTGVITTQGFLDFETKQSYHLTVKAFN--VPDEERCSFATVNIQ-LKGTNEYVPRFVS 3300
+ TG+IT ++ ++Y LTV+A + P E R S TV I+ L N+ PRF
Sbjct: 522 NKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQ 581
Query: 3301 KLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGI 3360
+Y EISEA G ++ + A+DR+ + Y I ++ F +++ TG + +
Sbjct: 582 LMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIENGDPQRVFNLSETTGILTLGKA 638
Query: 3361 LDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-----PPIFTLNIYSVQISE 3415
LDRE +R L + A + R TVN+ V D ND P N+ V+
Sbjct: 639 LDRESTDRYILIITASDG---RPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEA 695
Query: 3416 GVPIGTHVTFVSAFDSDS-IPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLP 3474
+G V A D D+ I +S GN N F I G I +L+RE
Sbjct: 696 NAFVGQ----VKATDPDAGINGQVHYSL----GNFNNLFRIT-SNGSIYTAVKLNREVRD 746
Query: 3475 IYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMTLQS 3532
Y L V+A D + +L + + DI+DN P+ T S V+ EN GT ++ +++
Sbjct: 747 YYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEA 806
Query: 3533 TDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVV----TK 3587
D DL N Y + + +F+L G LS R +D E D S+
Sbjct: 807 KDVDLGAN----VSYRIRSPEVKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAF 862
Query: 3588 DSGVPQMSSTGTVHITVIDQNDNP 3611
D TV + V D ND P
Sbjct: 863 DIYGTMPPGIATVTVIVKDMNDYP 886
Score = 216 bits (550), Expect = 5e-55
Identities = 244/842 (28%), Positives = 373/842 (44%), Gaps = 76/842 (9%)
Query: 74 LSESHALFAINSSTGALYTT--STIDRESLPSDVINLVVLSSAP-TYPTEVRVLVRDLND 130
L++ ++F + + Y T +DRE + ++ + P V + V D ND
Sbjct: 408 LNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQESEPVIVNIQVMDAND 467
Query: 131 NAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDIT 190
N P FP+ S V D G VI TA D+D GSNG +Y I+ G + G F ++ T
Sbjct: 468 NTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNG--EITYEILVGAQ-GDFIINKT 524
Query: 191 LNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDI---NDNP 247
+ G++ V Y L V+ D P R V ++ + N +P
Sbjct: 525 TG--------LITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSP 576
Query: 248 PVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITV 307
P F Y + E VG+ +L + A D EG + D F + TG++T+
Sbjct: 577 PRFPQLMYSLEISEAMRVGAVLLNLQATDR-EGDSITYAIENGDPQRVFNLSETTGILTL 635
Query: 308 REPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASV 367
+ LD E+ +Y L + A D G P T A I + DVNDN PV Y P
Sbjct: 636 GKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFD-PYLPRNLSVVEE 693
Query: 368 DENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALD 427
+ NA VG V A TD D+ NG + + GN F + S+ I A L+
Sbjct: 694 EANAFVGQVKA----TDPDA-GINGQVHYSL--GNFNNLFRITSN-----GSIYTAVKLN 741
Query: 428 RERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEE 487
RE Y L V +D AV R S +L I V DI+D+ PVF+ Y V + E
Sbjct: 742 REVRDYYELVVVATD-------GAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEEN 794
Query: 488 APPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDREL--- 544
P G+ + I A D D L AN+ Y I S +F + +G ++ S LD E
Sbjct: 795 LPAGTTILQIEAKDVD--LGANVSYRIRSPEVKHFFALHPFTGELSLLRS--LDYEAFPD 850
Query: 545 -ASQIVLNISARD-QGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTEL 602
+ I + A D G P A + V + D+ND PVFS+ Y V +A GT +
Sbjct: 851 QEASITFLVEAFDIYGTMPP-GIATVTVIVKDMNDYPPVFSK-RIYKGMVAPDAVKGTPI 908
Query: 603 LMLRATDGDLG--DNGTVRFSLQEAETDRRS--FRLDPVSGRLSTISSLDREEQAFYSLL 658
+ A D D VR+ + + + + F ++ SGR+ T +L+ E + L+
Sbjct: 909 TTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNEEPTTIFKLV 968
Query: 659 VLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYF-AHIKENEPGGSYITTVSATDPD 717
V+A D G P SS A + + +L + P F +Y + E G+ + +SA
Sbjct: 969 VVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISAA--- 1024
Query: 718 LGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD----GGNLQ 772
N ++ YSI +G + F +N +GVI LD E +T+Y L++ A NL+
Sbjct: 1025 -AINQSIVYSIVSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQADSLEVVLANLR 1083
Query: 773 SP---NQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLN--SNIS 827
P N A V I + D ++PPVF + Y V E+ + V V A+ D S ++
Sbjct: 1084 VPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMA 1143
Query: 828 Y-LITTGDQKGM--FAINQVTGQLTTANVIDREEQSFYQLKVVAS---GGTVTGDTMVNI 881
Y LI ++G F + TG + TA + +S+++ +V+A+ G ++G V +
Sbjct: 1144 YRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLV 1203
Query: 882 TV 883
+V
Sbjct: 1204 SV 1205
Score = 172 bits (436), Expect = 7e-42
Identities = 186/645 (28%), Positives = 296/645 (45%), Gaps = 61/645 (9%)
Query: 60 LVGTIQTRPGFTYRLS--ESHALFAINSSTGALYTTSTIDRESLPSDVINLVVLSSAP-- 115
L T + TY + + +F ++ +TG L +DRES ++ + P
Sbjct: 601 LQATDREGDSITYAIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGRPDG 660
Query: 116 TYPTEVRVLVRDLNDNAPVFPDP----SIVVTFKEDSSSGRQVILDTATDSDIGSNGVDH 171
T V ++V D+NDNAPVF DP ++ V +E ++ QV ATD D G NG H
Sbjct: 661 TSTATVNIVVTDVNDNAPVF-DPYLPRNLSVVEEEANAFVGQV---KATDPDAGINGQVH 716
Query: 172 RSYRIIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRR 231
S GN FR IT N S + + L+REV Y+L+V D R
Sbjct: 717 YSL----GNFNNLFR--ITSNGS-------IYTAVKLNREVRDYYELVVVATDGAVHPRH 763
Query: 232 GYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD 291
L + + V DI+DN PVF +S Y V E+ G+++LQ+ A D D G N R R +
Sbjct: 764 STLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPE 823
Query: 292 EGTPFQMDPETGLITVREPLDFEA--RRQYSLT--VQAMDRGVPSLTGRAEALIQLLDVN 347
F + P TG +++ LD+EA ++ S+T V+A D G A + + D+N
Sbjct: 824 VKHFFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMN 883
Query: 348 DNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHF 407
D PV R + V +A GT + + DAD P + V+ + Q +
Sbjct: 884 DYPPVFSKRIYK-----GMVAPDAVKGTPITTVYAEDADPPGLPAS-RVRYRVDDVQFPY 937
Query: 408 EVQSSKVPNLS-LIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVN 466
+V S + L+ E + L V D+ G P + + ++V LV+
Sbjct: 938 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDD-GEP---VMSSSATVKILVLHPG 993
Query: 467 DINDHPPVFSQQVYR-VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHI 525
+I P F+Q+ YR +SE A G+ V ISA + +N ++ YSIVSGN F I
Sbjct: 994 EI----PRFTQEEYRPPPVSELATKGTMVGVISA----AAINQSIVYSIVSGNEEDTFGI 1045
Query: 526 SEHSGLVTTGSSGGLDRELASQIVLNISA-------RDQGVHPKVSYAQLVVTLLDVNDE 578
+ +G++ +G LD E + VL + A + V K + A++ + + D N+
Sbjct: 1046 NNITGVIYV--NGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNH 1103
Query: 579 KPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTV--RFSLQEAETDRRSFRLDP 636
PVF Q + Y V E+A T +L ++ATD D G+ + R + + + F ++
Sbjct: 1104 PPVF-QKKFYIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVET 1162
Query: 637 VSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLD 681
+G + T ++++ V+ATD S A + VS+++
Sbjct: 1163 YTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVN 1207
Score = 165 bits (417), Expect = 1e-39
Identities = 189/731 (25%), Positives = 310/731 (42%), Gaps = 61/731 (8%)
Query: 2946 INRHSFIV-TSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 3004
+N HS +V K I V I + D NDN+P F Y+ V + VGT +
Sbjct: 109 MNIHSIVVQVQCINKKVGTIIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFT 168
Query: 3005 VTAID----DKDFGLNSEVEYFISND-------NHLGKFKLDNDTGWISVASSLISDLNQ 3053
+ D D D G N ++EY I + +L + + T + V DL
Sbjct: 169 GFSGDNGATDIDDGPNGQIEYVIQYNPDDPDRAQNLNERRTTTTTLTVDVLDG--DDLGP 226
Query: 3054 NFFITVTAKD-KGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVS 3112
F V + + PL+ QA + TPE + + P +I
Sbjct: 227 MFLPCVLVPNTRDCRPLTYQAAI------PELRTPE--ELNPIIVTPPIQAIDQDRNIQP 278
Query: 3113 ARDRDAAMNGLIKYSISSGNEEG---IFAINSSTGILTLAKALDYELCQKHEMTISAIDG 3169
DR I YSI G E F ++ T L+L + ++ + QK ++ I A
Sbjct: 279 PSDRPG-----ILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 333
Query: 3170 GWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTV---------IHLNATD 3220
+ + + ++D N+ SP F Y +LE+AP G T+ + + A D
Sbjct: 334 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 393
Query: 3221 AD-SGTNAVIAYTVQSSDSDLFVIDPN--TGVITTQGFLDFETKQSYHLTVKAFNVPDEE 3277
D T + + + +F + T +T +D E +Q+Y ++ AF+ E
Sbjct: 394 KDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAFDGVQES 453
Query: 3278 RCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLI 3337
VNIQ+ N+ P F Y + G V ++ A D D G++GE+ Y I
Sbjct: 454 EP--VIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI 511
Query: 3338 FGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLD 3397
+ + F INK TG I ++ ++ +L V A + TV + VL
Sbjct: 512 LVGA-QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLP 570
Query: 3398 AND--PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSI 3455
N+ PP F +YS++ISE + +G + + A D + +Y I +G+ F++
Sbjct: 571 PNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDREG----DSITYAIENGDPQRVFNL 626
Query: 3456 NPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--VS 3513
+ TG +T+ LDRE+ Y L + A D G P T +A++ + + D+NDN P+ +
Sbjct: 627 SETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVNDNAPVFDPYLP 685
Query: 3514 EGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREID 3573
+ + V +++TDPD N G Y S G + F +++ G + T +++
Sbjct: 686 RNLSVVEEEANAFVGQVKATDPDAGIN-GQVHY---SLGNFNNLFRITSNGSIYTAVKLN 741
Query: 3574 REQIADFY-LSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGI 3632
RE + D+Y L VV D V ST T+ I V+D +DN V NL G
Sbjct: 742 RE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTT 800
Query: 3633 LGSVKPQDPDV 3643
+ ++ +D D+
Sbjct: 801 ILQIEAKDVDL 811
Score = 139 bits (351), Expect = 5e-32
Identities = 174/701 (24%), Positives = 282/701 (40%), Gaps = 111/701 (15%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV-----SARDRDAAMNGLIKYSIS 3129
V I V + N ++P F AT+ E +G+ + T A D D NG I+Y I
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192
Query: 3130 SGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
++ A N + RT ++TV+V+D +D
Sbjct: 193 YNPDDPDRAQNLNE-----------------------------RRTTTTTLTVDVLDGDD 223
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD---------- 3239
P+FL P + P + ++ +Q+ D D
Sbjct: 224 LGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPPSDRP 283
Query: 3240 ----------------LFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFAT 3283
F + P T ++ ++ + Q + L +KA +FA
Sbjct: 284 GILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFAG 343
Query: 3284 VNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE---------VFASDRDLGTDGEVH 3334
++I++ N P F Y I E+AP G + + + A D+D+ +
Sbjct: 344 LHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPE 403
Query: 3335 YLIFGNSRKKGFQINKKTGQIYVSGI--LDREKEERVSLKVLAKNFGSIRGADIDEVTVN 3392
+F N F + + Y++ + +DRE+++ + + A F ++ + + V VN
Sbjct: 404 LHLFLNDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITA--FDGVQ--ESEPVIVN 459
Query: 3393 VTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENG 3451
+ V+DAND P F Y V + + G V ++A D+D S +Y I G + G
Sbjct: 460 IQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADE-GSNGEITYEILVGAQ-G 517
Query: 3452 AFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNG---- 3507
F IN TG IT+ ++ Y L+V A D+ P+ ++ V +E + N
Sbjct: 518 DFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPP 577
Query: 3508 --PMLTVSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLS-TAG 3564
P L S E+ E R G +++ LQ+TD +G Y + G F+LS T G
Sbjct: 578 RFPQLMYSL-EISEAMRVGAVLLNLQATD-----REGDSITYAIENGDPQRVFNLSETTG 631
Query: 3565 VLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDN-----PSQSRTVEI 3619
+L+ + +DRE D Y+ ++T G P +ST TV+I V D NDN P R + +
Sbjct: 632 ILTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSV 690
Query: 3620 FVNYYGNLFPGGILGSVKPQDPD--VLDSFHCSLTSGVTSLFSIP--GGTCDLNSQPRST 3675
V N F +G VK DPD + H SL +LF I G R
Sbjct: 691 -VEEEANAF----VGQVKATDPDAGINGQVHYSL-GNFNNLFRITSNGSIYTAVKLNREV 744
Query: 3676 DGTFDLTVLSNDGV----HSTVTSNIRVFFAGFSNATVDNS 3712
++L V++ DG HST+T I+V ++ NS
Sbjct: 745 RDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNS 785
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 329 bits (843), Expect = 5e-89
Identities = 246/764 (32%), Positives = 380/764 (49%), Gaps = 50/764 (6%)
Query: 80 LFAINSSTGALYTTST-IDRESLPSDV---------INLVVLSSAPTYPTEVRVLVRDLN 129
L I TG ++TT IDRE L + + + + +L ++R L+ D+N
Sbjct: 106 LIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN 165
Query: 130 DNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDI 189
DNAP+FP I ++ E+S+ + L A D D+G NGV ++Y +I+ F LD+
Sbjct: 166 DNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGV--QNYELIKSQNI--FGLDV 221
Query: 190 TLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPV 249
P G+ L+ + LDRE Y + V+VED G P+R + V+V D NDN PV
Sbjct: 222 IETPEGD-KMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV 280
Query: 250 FGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD-----EGTPFQMDPETGL 304
F + + +PE+A VG+SV Q+ A DAD G NA I + + F ++ TGL
Sbjct: 281 FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL 340
Query: 305 ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYF-PATSR 363
IT++EPLD E + L V A D G+ + RA L+ + DVNDN P + RY +
Sbjct: 341 ITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVND 398
Query: 364 YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
+ EN + T +AL+TVTD D+ NG ++ + + F ++ N L++ A
Sbjct: 399 TVVLSENIPLNTKIALITVTDKDAD-HNGRVTCFT---DHEIPFRLR-PVFSNQFLLENA 453
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+ LD E Y + + +D G PP + A L I V D ND+ PVF+Q V+
Sbjct: 454 AYLDYESTKEYAIKLLAAD-AGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVS 506
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ E PG + +SATD DSG NA + Y ++ + F + +G++T LDRE
Sbjct: 507 IPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKK--LDRE 563
Query: 544 LASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELL 603
+ + I A+D GV P S + V+++D ND PVF+ E Y V EN P +
Sbjct: 564 KEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNE-YKFYVPENLPRHGTVG 622
Query: 604 MLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATD 663
++ TD D GDN V S+ + D F +D +G + S DRE+Q Y+ V A D
Sbjct: 623 LITVTDPDYGDNSAVTLSILDENDD---FTIDSQTGVIRPNISFDREKQESYTFYVKAED 679
Query: 664 LGSPPQSSMARINVSLLDINDNSPVF----YPVQYFAHIKENEPGGSYITTVSATDPDLG 719
G +SS A++ ++++D+NDN PVF Y Y + P G+ + V A D D G
Sbjct: 680 GGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTG 738
Query: 720 TNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSP-NQA 777
N V+YSI G+ R F ++ ++G I+ D + +++ + A D G S +
Sbjct: 739 MNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVV 798
Query: 778 IVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD 821
IV + V ++ N + +++ + V + VS+ T D
Sbjct: 799 IVNLFVNESVTNATLINELVRKSIE-APVTPNTEIADVSSPTSD 841
Score = 298 bits (763), Expect = 9e-80
Identities = 233/759 (30%), Positives = 365/759 (48%), Gaps = 38/759 (5%)
Query: 1670 VRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEIT 1729
+R EE T G +FT G + A + R++ C Y V+V AI F + ++
Sbjct: 107 IRIEEDT-GEIFTTGARIDREKLCAGIPRDEH-CFYEVEV-AILPDEIF---RLVKIRFL 160
Query: 1730 LQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRI 1789
++DINDN P+FP ++++++ EN SK A+D D G N + Y +I + + F +
Sbjct: 161 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK-SQNIFGL 219
Query: 1790 D----PESG---DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTP 1839
D PE LI + LDRE + Y + V+ +DG +SS + ++V+D ND+ P
Sbjct: 220 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 279
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE---DDEDGIFFLNPITG 1896
F IPE+ G+ V + ATD D G N +I + + + +F LN TG
Sbjct: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
Query: 1897 VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLN------SYS 1950
+ + LD E + L V A DGG V N+ DVNDN P + + +
Sbjct: 340 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 399
Query: 1951 TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKA-LDRE 2009
L EN+P+ + + + VTD D N ++T V N L A LD E
Sbjct: 400 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 459
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTV 2068
S Y + + D + P ++ +A + I + D NDN P F +T IPEN
Sbjct: 460 STKEYAIKLLAADAGKPPLNQ---SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
Query: 2069 VFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
+ K ATD DSGPN+ I Y L +FS+ G + + +LDRE+ Y T++A D
Sbjct: 517 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 576
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P L+S+ V V ++D NDN+P+F YK + EN + + D D G N
Sbjct: 577 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSA 636
Query: 2189 VRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIV 2248
V I+ + N +F IDS TG I DREK +Y V+A D G R+ ++ V+I
Sbjct: 637 VTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
Query: 2249 LLDINDFVPVFELSPYSVNVPENL-GTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDN 2306
++D+ND PVF + PY+ + L T P T++ QV+A D+D G N+++ Y + GGN +
Sbjct: 695 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
Query: 2307 AFTL-SASGELGVTQSLDRETKERFVLMITATDSGSP-ALTGTGTINVIVDDVNDNVPTF 2364
F + +G + + + D +++ A D G P +L +N+ V++ N T
Sbjct: 755 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA-TL 813
Query: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIG 2403
++ +I T++ V++ +D K V + G
Sbjct: 814 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAG 852
Score = 295 bits (755), Expect = 8e-79
Identities = 213/679 (31%), Positives = 336/679 (49%), Gaps = 47/679 (6%)
Query: 954 PLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNS 1013
P D H Y++E+ + +L V + + D+NDN+P+F +++ E+ +NS
Sbjct: 133 PRDEHC-FYEVEVAILPDEIFRL---VKIRFLIEDINDNAPLFPATVINISIPENSAINS 188
Query: 1014 RFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI----FPDG----QLYIKSELDRELQDR 1065
++ A D D G NG Y + + + FG+ P+G QL ++ ELDRE +D
Sbjct: 189 KYTLPAAVDPDVGINGVQNYELIKSQ--NIFGLDVIETPEGDKMPQLIVQKELDREEKDT 246
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAV 1125
YV+ V D S+T + V + D NDN P+F T E G+ V ++ A
Sbjct: 247 YVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHAT 306
Query: 1126 DKDFGPNGEVRYSFEMVQPD-----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
D D G N ++ +SF + + F L+A +G IT DRE T V+
Sbjct: 307 DADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE------TPNHKLLVL 360
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAP----KFLKDFYQATI--SESAANLTQVLRVSA 1234
A+D G+ + +A V V + D+NDN P +++ + T+ SE+ T++ ++
Sbjct: 361 ASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITV 417
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
+D D +NG + R + S + LDYE+T Y++ + A D+G P
Sbjct: 418 TDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPP 477
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
LN + L I + DENDN P F +S + V + EN G + V+ATD+DSG NA++ Y +
Sbjct: 478 LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-L 536
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFN 1414
G + FS+ TG + + KKLD E + Y I AKD G PP +S ++V + + D N
Sbjct: 537 LGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQN 596
Query: 1415 DNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEV 1474
DN P F + + EN+P +V +T DPD N ++ +I+ + + FTID
Sbjct: 597 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE---NDDFTIDSQ 653
Query: 1475 KGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI---- 1530
G I N DRE + VKA D R + VTI V D+NDN P+FI
Sbjct: 654 TGVIRPNISFDREKQESYTFYVKAEDGG---RVSRSSSAKVTINVVDVNDNKPVFIVPPY 710
Query: 1531 SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASA 1589
+ + PS G+V+ ++A D D G N E+ Y I+ G+T D F +D+ +G++ +
Sbjct: 711 NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEK 770
Query: 1590 LVPSQL-IYNLIVSATDLG 1607
+ L ++ ++V A DLG
Sbjct: 771 CDVTDLGLHRVLVKANDLG 789
Score = 278 bits (712), Expect = 7e-74
Identities = 218/680 (32%), Positives = 331/680 (48%), Gaps = 50/680 (7%)
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ 404
D+NDN P+ FPAT S+ EN+ + + L D D NG + +++
Sbjct: 163 DINDNAPL-----FPATVINISIPENSAINSKYTLPAAVDPDV-GINGVQNYELIKSQNI 216
Query: 405 RHFEV----QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVAS 460
+V + K+P L + K LDRE +Y + V V D G P RSS A
Sbjct: 217 FGLDVIETPEGDKMPQLIVQK---ELDREEKDTYVMKVKVEDG-GFPQ------RSSTAI 266
Query: 461 LVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYS---IVSG 517
L + V D ND+ PVF + V++ E AP G+ V+ + ATD D G NA + +S +VS
Sbjct: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
Query: 518 NGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVND 577
FH++ +GL+T LDRE L + A D G+ P + A ++V + DVND
Sbjct: 327 IARRLFHLNATTGLITIKEP--LDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVND 382
Query: 578 EKPVFS-----QPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR-S 631
P P V + EN P T++ ++ TD D NG V TD
Sbjct: 383 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-----CFTDHEIP 437
Query: 632 FRLDPVSGR---LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPV 688
FRL PV L + LD E Y++ +LA D G PP + A + + + D NDN+PV
Sbjct: 438 FRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPV 497
Query: 689 FYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTR 748
F I EN G + VSATD D G N + Y + F ++ ++G+++
Sbjct: 498 FTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVV 557
Query: 749 MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVAL 808
LDRE++ Y I+A D G + V ++++D DN PVF+ Y F V EN+
Sbjct: 558 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR 617
Query: 809 GYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA 868
VG ++ + D N + ++ D+ F I+ TG + DRE+Q Y V A
Sbjct: 618 HGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKA 677
Query: 869 -SGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDE 922
GG V + V I V D+NDN P F+ + + V+ + G +FQ AVD D
Sbjct: 678 EDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDT 737
Query: 923 GVNGMVLYSL-KQNPKNLFAINEKNGTISLLGPLDV-HAGSYQIEILASDMGVP-QLSSS 979
G+N V YS+ N ++LFAI+++ G I+L+ DV G +++ + A+D+G P L S
Sbjct: 738 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 797
Query: 980 VILTVYVHDVNDNSPVFDQL 999
VI+ ++V++ N+ + ++L
Sbjct: 798 VIVNLFVNESVTNATLINEL 817
Score = 278 bits (711), Expect = 1e-73
Identities = 213/704 (30%), Positives = 317/704 (45%), Gaps = 41/704 (5%)
Query: 613 GDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSM 672
GD +R E R+D R + + R+E FY + V P
Sbjct: 102 GDVPLIRIEEDTGEIFTTGARID----REKLCAGIPRDEHCFYEVEVAIL-----PDEIF 152
Query: 673 ARINVSLL--DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISA 730
+ + L DINDN+P+F I EN S T +A DPD+G NG Y +
Sbjct: 153 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 212
Query: 731 G------DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVL 784
D + + + LDREEK Y +++ DGG Q + AI+ ++V
Sbjct: 213 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 272
Query: 785 DTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMF 839
DT DN PVF + + EN +G V + A+ D+ N + + + +F
Sbjct: 273 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 332
Query: 840 AINQVTGQLTTANVIDREEQSFYQLKVVAS-GGTVTGDTMVNITVKDLNDNSP-----HF 893
+N TG +T +DREE ++L V+AS GG + MV + V D+NDN P +
Sbjct: 333 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 392
Query: 894 LQAI-ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVL-YSLKQNPKNLFAINEKNGTISL 951
+ + ++V + EN I D D NG V ++ + P L + +
Sbjct: 393 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN 452
Query: 952 LGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEP 1010
LD + Y I++LA+D G P L+ S +L + V D NDN+PVF Q V++ E+
Sbjct: 453 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 512
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMV 1070
+ KV A+D DSG N EI Y + + G L + +LDRE +D+Y+ +
Sbjct: 513 PGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTI 572
Query: 1071 VASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG 1130
+A D V PL++ V V V + D NDN P+F Y FY E VG ++ D D+G
Sbjct: 573 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYG 632
Query: 1131 PNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
N V S DF + + +G I FDRE ++F V A D G
Sbjct: 633 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREK------QESYTFYVKAEDGG-RVSR 685
Query: 1191 KDQATVHVYMKDINDNAPKFLKDFYQAT---ISESAANLTQVLRVSASDVDEGNNGLIHY 1247
A V + + D+NDN P F+ Y + + S T V +V A D D G N + Y
Sbjct: 686 SSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRY 745
Query: 1248 SIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
SI+ GN FAID +G +TL+ K D + ++++A D G
Sbjct: 746 SIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLG 789
Score = 264 bits (674), Expect = 2e-69
Identities = 214/729 (29%), Positives = 342/729 (46%), Gaps = 56/729 (7%)
Query: 718 LGTNGTVKYSISAGDRSRFQVNAQSGVISTRMA----------LDREEKTAYQLQIVATD 767
L T K GD ++ +G I T A + R+E Y++++
Sbjct: 89 LTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAI-- 146
Query: 768 GGNLQSPNQAIVTITVL--DTQDNPPVFSQVAYSFVVFENVALG--YHVGSVSASTMDLN 823
L +V I L D DN P+F + + EN A+ Y + + + +N
Sbjct: 147 ---LPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGIN 203
Query: 824 SNISY-LITTGDQKGMFAINQVTG----QLTTANVIDREEQSFYQLKVVASGGTV---TG 875
+Y LI + + G+ I G QL +DREE+ Y +KV G +
Sbjct: 204 GVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSS 263
Query: 876 DTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQN 935
++ ++V D NDN P F + V++ EN G S+ Q A D D G N + +S
Sbjct: 264 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 323
Query: 936 PKN----LFAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVN 990
N LF +N G I++ PLD ++++ +LASD G+ + + ++ V V DVN
Sbjct: 324 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVN 381
Query: 991 DNSPVFD------QLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAF 1044
DN P D ++ V LSE+ P+N++ + +DKD+ NG +
Sbjct: 382 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 1045 GIFPDGQLYIKSE-LDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNST 1103
+F + L + LD E Y + ++A+D PL+ + + + ++D NDN P+F +
Sbjct: 442 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 501
Query: 1104 NYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM-VQPDFELHAISGEITNTHQFD 1162
T E G + KVSA D D GPN E+ Y P+F L +G +T + D
Sbjct: 502 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 561
Query: 1163 RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISES 1222
RE + + FT++A D G+P PL TV V + D NDN+P F + Y+ + E+
Sbjct: 562 REKEDK------YLFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPEN 614
Query: 1223 AANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYS 1282
V ++ +D D G+N + SI+ N++ F IDS +G + D E +Y+
Sbjct: 615 LPRHGTVGLITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYT 672
Query: 1283 LVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF---PKSTLFVDVLENMRIGELVSSVTA 1339
++A D G + +S+ + I+++D NDN P F P + + VL + G +V V A
Sbjct: 673 FYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIA 732
Query: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPP 1399
D+D+G NA++ YSI G N F+I TG+I L +K D L+++ + A D G+P
Sbjct: 733 VDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP- 791
Query: 1400 RSSTMSVVI 1408
S SVVI
Sbjct: 792 -DSLFSVVI 799
Score = 250 bits (638), Expect = 3e-65
Identities = 233/805 (28%), Positives = 367/805 (45%), Gaps = 72/805 (8%)
Query: 1425 IFKSIVENIPIGTSVISVTAH-DPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTN-A 1482
I + I EN+ IG + + P+ + + + ++ + I+E G I+T A
Sbjct: 62 IREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGA 121
Query: 1483 EIDREFAN---------LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQN 1533
IDRE +E+ V + + L + L+ D+NDN P+F +
Sbjct: 122 RIDREKLCAGIPRDEHCFYEVEVAILPDEI------FRLVKIRFLIEDINDNAPLFPATV 175
Query: 1534 ALAADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASAL 1590
+ P ++ I S T A DPD G NG YE+I +++ GD ++ +
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGD-KMPQLI 234
Query: 1591 VPSQL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGE 1642
V +L Y + V D G +R ST L + + + PVF + + + E
Sbjct: 235 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENA 294
Query: 1643 PIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQG 1701
P+GT+V + A + G A + + ++ RLF + TG+I LDRE+
Sbjct: 295 PVGTSVTQLHATDADIGENAKIHFSFSNL--VSNIARRLFHLNATTGLITIKEPLDREET 352
Query: 1702 ACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGD 1755
L+ + S RA V + + D+NDN P + + + ENI
Sbjct: 353 PNHKLL----VLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPL 408
Query: 1756 GSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGD---LIATRRLDRERRSKYSL 1812
+KI +T D D N V T + + FR+ P + L LD E +Y++
Sbjct: 409 NTKIALITVTDKDADHNGRV--TCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAI 466
Query: 1813 -LVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD 1868
L+ AD G L S M + I V D ND+ P F++ + IPE+ PG + + ATD
Sbjct: 467 KLLAADAGKPPLNQSAM-LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDA 525
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT- 1927
DSG N EI Y++ D F L+ TG+ + + LD E + Y+ T+ A+D G T
Sbjct: 526 DSGPNAEINYLLGPDAPPE-FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTS 584
Query: 1928 -IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
+ V+ +I+D NDN P+F+ N Y + ENLP TV + VTD D G NS +T SI
Sbjct: 585 NVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-- 642
Query: 1987 DSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
D FT+D + GV++ + DRE Q Y V+ D ++ S S+A+V+I ++DVN
Sbjct: 643 DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRS---SSAKVTINVVDVN 699
Query: 2046 DNPPTFLSPKLTY-----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
DN P F+ P Y +P P TVVF+ A D D+G N+ + Y+++ GN +
Sbjct: 700 DNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLF 756
Query: 2101 TID---GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
ID G + L + D ++ + + V A D GQP S +V + ++ + N
Sbjct: 757 AIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINE 816
Query: 2158 LYKVEINENTLTGTDIIQVFAADGD 2182
L + I T+I V + D
Sbjct: 817 LVRKSIEAPVTPNTEIADVSSPTSD 841
Score = 249 bits (637), Expect = 4e-65
Identities = 217/719 (30%), Positives = 323/719 (44%), Gaps = 67/719 (9%)
Query: 2203 RIDSVTGAI-TVAKPLDREKT----PTYHLTVQATDRGSTPRTDTSTVSIVLL--DINDF 2255
RI+ TG I T +DREK P + P V I L DIND
Sbjct: 108 RIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDN 167
Query: 2256 VPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA--- 2312
P+F + ++++PEN + L A D D G N +Y L N F L
Sbjct: 168 APLFPATVINISIPENSAINSKYTLPA-AVDPDVGINGVQNYELI--KSQNIFGLDVIET 224
Query: 2313 -----SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASK 2367
+L V + LDRE K+ +V+ + D G P + T + V V D NDN P F
Sbjct: 225 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 284
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN-------SQFTINPSTGQIITS 2420
+IPE+AP GT V ++A+DAD +NA I N F +N +TG I
Sbjct: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
Query: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYV-----THI 2475
LDRE N+ L+V+ SD G + + VLV VTDVNDN P V T +
Sbjct: 345 EPLDREETPNHKLLVLASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVV 401
Query: 2476 PSPTLP-GSFVFAVTVTDADIGPNS--------ELHYSLSGRNSEKFHIDPLRGAIMAAG 2526
S +P + + +TVTD D N E+ + L S +F ++ A
Sbjct: 402 LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN-----AAYL 456
Query: 2527 PLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSSL 2585
E + D G P S + ++ ++ D P T PEN
Sbjct: 457 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
Query: 2586 VTTITGSSLRGEPMS--YYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARD 2643
+ ++ + P + Y+ + F +D+ TG +++ + LD EK KY+ I A+D
Sbjct: 517 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 576
Query: 2644 GGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR--KILTVSAMDKDSGPNG 2701
G PP +S + ++++D NDN+P+F + + + ENL PR + ++ D D G N
Sbjct: 577 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENL-PRHGTVGLITVTDPDYGDNS 635
Query: 2702 QLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMI 2761
+ I++ N + F+I+ TG IR DREK Y +K+ D G S+S+S KV I
Sbjct: 636 AVTLSILDEN--DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
Query: 2762 NILDENDNAPRF-----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL 2816
N++D NDN P F + + +P +P G V +V D D G+NA RYSI+ +
Sbjct: 694 NVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNT 752
Query: 2817 P--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVS----TDVTIFVTDINDNA 2869
F I+ TG+I + + D +R+ V A+D G S V +FV + NA
Sbjct: 753 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA 811
Score = 236 bits (603), Expect = 3e-61
Identities = 209/719 (29%), Positives = 335/719 (46%), Gaps = 68/719 (9%)
Query: 2410 INPSTGQIITS-ALLDRET------KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
I TG+I T+ A +DRE +D + V A P+ + + + D+NDN
Sbjct: 109 IEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEV-EVAILPDEIFRLVKIRFLIEDINDN 167
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGA- 2521
P F IP + S D D+G N +Y L ++ F +D +
Sbjct: 168 APLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELI-KSQNIFGLDVIETPE 226
Query: 2522 ------IMAAGPLNGASEVTFSVHVK-DGGSFPKTDSTTVTVRFVNKAD--FPKVRAKEQ 2572
++ L+ + T+ + VK + G FP+ ST + V + P + E
Sbjct: 227 GDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 286
Query: 2573 TFMFPENQPVSSLVTTITGSSLR-GEPMSYYIASGNLGNT-----FQIDQLTGQVSISQP 2626
PEN PV + VT + + GE + + NL + F ++ TG ++I +P
Sbjct: 287 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 346
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEI------LE 2680
LD E+ + + + A DGG P + +++T DVNDN P ++ + E
Sbjct: 347 LDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSE 404
Query: 2681 NLSPR-KILTVSAMDKDSGPNGQL----DYEI---VNGNMENSFSINHATGEIRSVRPLD 2732
N+ KI ++ DKD+ NG++ D+EI + N F + +A LD
Sbjct: 405 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY-------LD 457
Query: 2733 REKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIF-SAHVPENSPLGYTV 2791
E Y + + ++D G P + S + I + DENDNAP F+Q F + +PEN+ G +
Sbjct: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 517
Query: 2792 TRVTTSDEDIGINAISRYSI-MDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDS 2850
+V+ +D D G NA Y + DA F+++ TG + + + L+RE D+Y + A D+
Sbjct: 518 MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 577
Query: 2851 GWT-VSTDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQV 2907
G ++++VT+FV+ D NDN+P F+ Y PE V + TDPD G N V
Sbjct: 578 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 637
Query: 2908 FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET 2967
I +++ F I++ TG I N++ F ++F V + D G+ S S
Sbjct: 638 TLSILDENDDFTIDSQTGVI-------RPNIS-FDREKQESYTFYVKAEDGGRVSRSSSA 689
Query: 2968 TVTINIVDSNDNAPQFLKSKY---FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFIS 3024
VTIN+VD NDN P F+ Y + V + GT + +V A+D+ D G+N+EV Y I
Sbjct: 690 KVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDN-DTGMNAEVRYSIV 748
Query: 3025 NDNHLGKFKLDNDTGWISVASSL-ISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTE 3081
N F +D +TG I++ ++DL + + V A D G P L S V++ V E
Sbjct: 749 GGNTRDLFAIDQETGNITLMEKCDVTDLGLH-RVLVKANDLGQPDSLFSVVIVNLFVNE 806
Score = 220 bits (560), Expect = 3e-56
Identities = 187/661 (28%), Positives = 306/661 (46%), Gaps = 38/661 (5%)
Query: 2858 VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG-QVFYFIKSQSE 2916
+ + DINDNAP F T + PE + I SK T A DPD G NG Q + IKSQ+
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 2917 YFRINATTGE-------IFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTV 2969
+ T E I K++ + + T V + D G P S +
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVE---------DGGFPQRSSTAIL 267
Query: 2970 TINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN-DNH 3028
+++ D+NDN P F +++ + +N VGT + ++ A D D G N+++ + SN ++
Sbjct: 268 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD-ADIGENAKIHFSFSNLVSN 326
Query: 3029 LGK--FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
+ + F L+ TG I++ L + N + V A D G P ++A V + VT+ N +
Sbjct: 327 IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNV 384
Query: 3087 PEFSQSHM------SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
P ++ + + E+ + + + ++ D+DA NG + + +
Sbjct: 385 PSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF 444
Query: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYF 3200
S+ +L A LDYE +++ + + A D G + + V D NDN+PVF
Sbjct: 445 SNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT 504
Query: 3201 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFET 3260
++ EN G ++ ++ATDADSG NA I Y + F +D TG++T LD E
Sbjct: 505 VSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREK 564
Query: 3261 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 3320
+ Y T+ A + S TV + + N+ P F Y F + E P+ VG +
Sbjct: 565 EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLI 624
Query: 3321 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGS 3380
+D D G + V I F I+ +TG I + DREK+E + V A++ G
Sbjct: 625 TVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGR 682
Query: 3381 IRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPI---GTHVTFVSAFDSDSIPS 3436
+ + +VT+N V+D ND P+F + Y+ +P GT V V A D+D+ +
Sbjct: 683 VSRSSSAKVTIN--VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 740
Query: 3437 WSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASL 3496
+ Y I GN F+I+ +TG IT+ + D L ++ + V A D G P + S +
Sbjct: 741 -AEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 799
Query: 3497 L 3497
+
Sbjct: 800 V 800
Score = 219 bits (558), Expect = 5e-56
Identities = 181/643 (28%), Positives = 290/643 (45%), Gaps = 31/643 (4%)
Query: 2919 RINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSND 2978
RI TGEIF + + + + H F + + I D ND
Sbjct: 108 RIEEDTGEIFTTGA-RIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIND 166
Query: 2979 NAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY-FISNDNHLGKFKLDND 3037
NAP F + + +N + +K A+D D G+N Y I + N G ++
Sbjct: 167 NAPLFPATVINISIPENSAINSKYTLPAAVDP-DVGINGVQNYELIKSQNIFGLDVIETP 225
Query: 3038 TG----WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSH 3093
G + V L + + + V +D G P SS A + ++VT+ N + P F ++
Sbjct: 226 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETE 285
Query: 3094 MSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS---SGNEEGIFAINSSTGILTLAK 3150
+ +IPE+ +G+ V + A D D N I +S S S +F +N++TG++T+ +
Sbjct: 286 IEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKE 345
Query: 3151 ALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL-- 3204
LD E H++ + A DGG + V VNV DVNDN P ++ + TV+
Sbjct: 346 PLDREETPNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 403
Query: 3205 ENAPSGTTVIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQS 3263
EN P T + + TD D+ N V +T L + N ++ +LD+E+ +
Sbjct: 404 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKE 463
Query: 3264 YHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFAS 3323
Y + + A + A + I++K N+ P F I E G + +V A+
Sbjct: 464 YAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSAT 523
Query: 3324 DRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRG 3383
D D G + E++YL+ G F ++++TG + V LDREKE++ +LAK+ G
Sbjct: 524 DADSGPNAEINYLL-GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGV--P 580
Query: 3384 ADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY 3442
VTV V+++D ND P+FT N Y + E +P V ++ D D +
Sbjct: 581 PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY---GDNSAV 637
Query: 3443 FIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLED 3502
+ +EN F+I+ QTG I DRE Y V A D G S + SA + + + D
Sbjct: 638 TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVD 697
Query: 3503 INDNGPMLTV-----SEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
+NDN P+ V S V+ + PGT+V + + D D N
Sbjct: 698 VNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 740
Score = 186 bits (471), Expect = 7e-46
Identities = 165/558 (29%), Positives = 262/558 (46%), Gaps = 35/558 (6%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYS-ISSGNE 3133
+ + + N + P F + ++ +IPE+ +I S +A D D +NG+ Y I S N
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 3134 EGIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ I + G L + K LD E + M + DGG+ R+ + V+V D ND
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 276
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD----LFVIDP 3245
N PVF + ++ ENAP GT+V L+ATDAD G NA I ++ + S+ LF ++
Sbjct: 277 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 336
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
TG+IT + LD E ++ L V A + + VN+ N+ VP +
Sbjct: 337 TTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVN 394
Query: 3306 EI------SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
+ SE P T + + +D+D +G V + F++ ++
Sbjct: 395 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF---TDHEIPFRLRPVFSNQFLLE 451
Query: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
+ LD E + ++K+LA + G + + + V D ND P+FT + +V I E
Sbjct: 452 NAAYLDYESTKEYAIKLLAADAG--KPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPE 509
Query: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
G + VSA D+DS P+ + +Y +G + FS++ +TG +TV +LDRE
Sbjct: 510 NNSPGIQLMKVSATDADSGPN-AEINYLLGP-DAPPEFSLDRRTGMLTVVKKLDREKEDK 567
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
Y ++LA D+G P T + ++ V++ D NDN P+ T +E + V EN V + T
Sbjct: 568 YLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVT 627
Query: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSL-STAGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
DPD N LS F++ S GV+ DRE+ + V +D G
Sbjct: 628 DPDYGDNSA----VTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRV 683
Query: 3593 QMSSTGTVHITVIDQNDN 3610
SS+ V I V+D NDN
Sbjct: 684 SRSSSAKVTINVVDVNDN 701
Score = 110 bits (275), Expect = 3e-23
Identities = 132/499 (26%), Positives = 210/499 (42%), Gaps = 41/499 (8%)
Query: 3234 QSSDSDLFVIDPNTGVITTQGF-LDFET-------KQSYHLTVKAFNVPDEERCSFATVN 3285
++ D L I+ +TG I T G +D E + V+ +PDE F V
Sbjct: 100 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDE---IFRLVK 156
Query: 3286 IQ--LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
I+ ++ N+ P F + + I E + + A D D+G +G +Y + +
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 3344 KGFQI-----NKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDA 3398
G + K Q+ V LDRE+++ +KV ++ G + + + V+VT D
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT--DT 274
Query: 3399 NDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FS 3454
ND P+F V I E P+GT VT + A D+D I ++ + + N A F
Sbjct: 275 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFH 333
Query: 3455 INPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--- 3511
+N TG IT+ LDRE P + L VLA D G A A +LV + D+NDN P +
Sbjct: 334 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR--AMVLVNVTDVNDNVPSIDIRY 391
Query: 3512 ----VSEGEVMENKRP-GTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVL 3566
V++ V+ P T + + TD D N G T + P S +L
Sbjct: 392 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHN-GRVTCFTDHEIPFRLRPVFSNQFLL 450
Query: 3567 STTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGN 3626
+D E ++ + ++ D+G P ++ + + I V D+NDN + V+ N
Sbjct: 451 ENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN 510
Query: 3627 LFPGGILGSVKPQDPDVLDSFHCSLTSGVT-----SLFSIPGGTCDLNSQPRSTDGTFDL 3681
PG L V D D + + G SL G + R + +
Sbjct: 511 NSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF 570
Query: 3682 TVLSNDGVHSTVTSNIRVF 3700
T+L+ D +TSN+ VF
Sbjct: 571 TILAKDNGVPPLTSNVTVF 589
Score = 34.7 bits (78), Expect = 2.4
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 27/161 (16%)
Query: 4505 VPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPDNIPP 4564
V A+ G+ V+ + + +++ C Q KA +K +N + P+ P
Sbjct: 847 VAAVAGTITVVVVIFITAVVRCRQAPHLKAA------------QKNMQNSEWATPN---P 891
Query: 4565 YGDDMTV----RKQPEGNPKP---DIIERENPYLIYDETDIPHNSETIPSAPLASPEQEI 4617
M + +K+ + +PK +++ E D+ D N T+ P+ EQ +
Sbjct: 892 ENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKA--DDVDSDGNRVTL-DLPIDLEEQTM 948
Query: 4618 EHYD-IDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPL 4657
Y+ + ++ P D+ +HYK S P F IQ +PL
Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKS-ASPQPAFQIQPETPL 988
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 329 bits (843), Expect = 5e-89
Identities = 246/764 (32%), Positives = 380/764 (49%), Gaps = 50/764 (6%)
Query: 80 LFAINSSTGALYTTST-IDRESLPSDV---------INLVVLSSAPTYPTEVRVLVRDLN 129
L I TG ++TT IDRE L + + + + +L ++R L+ D+N
Sbjct: 106 LIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN 165
Query: 130 DNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDI 189
DNAP+FP I ++ E+S+ + L A D D+G NGV ++Y +I+ F LD+
Sbjct: 166 DNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGV--QNYELIKSQNI--FGLDV 221
Query: 190 TLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPV 249
P G+ L+ + LDRE Y + V+VED G P+R + V+V D NDN PV
Sbjct: 222 IETPEGD-KMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV 280
Query: 250 FGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD-----EGTPFQMDPETGL 304
F + + +PE+A VG+SV Q+ A DAD G NA I + + F ++ TGL
Sbjct: 281 FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL 340
Query: 305 ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYF-PATSR 363
IT++EPLD E + L V A D G+ + RA L+ + DVNDN P + RY +
Sbjct: 341 ITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVND 398
Query: 364 YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
+ EN + T +AL+TVTD D+ NG ++ + + F ++ N L++ A
Sbjct: 399 TVVLSENIPLNTKIALITVTDKDAD-HNGRVTCFT---DHEIPFRLR-PVFSNQFLLENA 453
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+ LD E Y + + +D G PP + A L I V D ND+ PVF+Q V+
Sbjct: 454 AYLDYESTKEYAIKLLAAD-AGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVS 506
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ E PG + +SATD DSG NA + Y ++ + F + +G++T LDRE
Sbjct: 507 IPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKK--LDRE 563
Query: 544 LASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELL 603
+ + I A+D GV P S + V+++D ND PVF+ E Y V EN P +
Sbjct: 564 KEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNE-YKFYVPENLPRHGTVG 622
Query: 604 MLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATD 663
++ TD D GDN V S+ + D F +D +G + S DRE+Q Y+ V A D
Sbjct: 623 LITVTDPDYGDNSAVTLSILDENDD---FTIDSQTGVIRPNISFDREKQESYTFYVKAED 679
Query: 664 LGSPPQSSMARINVSLLDINDNSPVF----YPVQYFAHIKENEPGGSYITTVSATDPDLG 719
G +SS A++ ++++D+NDN PVF Y Y + P G+ + V A D D G
Sbjct: 680 GGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTG 738
Query: 720 TNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSP-NQA 777
N V+YSI G+ R F ++ ++G I+ D + +++ + A D G S +
Sbjct: 739 MNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVV 798
Query: 778 IVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD 821
IV + V ++ N + +++ + V + VS+ T D
Sbjct: 799 IVNLFVNESVTNATLINELVRKSIE-APVTPNTEIADVSSPTSD 841
Score = 298 bits (763), Expect = 9e-80
Identities = 233/759 (30%), Positives = 365/759 (48%), Gaps = 38/759 (5%)
Query: 1670 VRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEIT 1729
+R EE T G +FT G + A + R++ C Y V+V AI F + ++
Sbjct: 107 IRIEEDT-GEIFTTGARIDREKLCAGIPRDEH-CFYEVEV-AILPDEIF---RLVKIRFL 160
Query: 1730 LQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRI 1789
++DINDN P+FP ++++++ EN SK A+D D G N + Y +I + + F +
Sbjct: 161 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK-SQNIFGL 219
Query: 1790 D----PESG---DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTP 1839
D PE LI + LDRE + Y + V+ +DG +SS + ++V+D ND+ P
Sbjct: 220 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 279
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE---DDEDGIFFLNPITG 1896
F IPE+ G+ V + ATD D G N +I + + + +F LN TG
Sbjct: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
Query: 1897 VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLN------SYS 1950
+ + LD E + L V A DGG V N+ DVNDN P + + +
Sbjct: 340 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 399
Query: 1951 TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKA-LDRE 2009
L EN+P+ + + + VTD D N ++T V N L A LD E
Sbjct: 400 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 459
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTV 2068
S Y + + D + P ++ +A + I + D NDN P F +T IPEN
Sbjct: 460 STKEYAIKLLAADAGKPPLNQ---SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
Query: 2069 VFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
+ K ATD DSGPN+ I Y L +FS+ G + + +LDRE+ Y T++A D
Sbjct: 517 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 576
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P L+S+ V V ++D NDN+P+F YK + EN + + D D G N
Sbjct: 577 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSA 636
Query: 2189 VRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIV 2248
V I+ + N +F IDS TG I DREK +Y V+A D G R+ ++ V+I
Sbjct: 637 VTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
Query: 2249 LLDINDFVPVFELSPYSVNVPENL-GTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDN 2306
++D+ND PVF + PY+ + L T P T++ QV+A D+D G N+++ Y + GGN +
Sbjct: 695 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
Query: 2307 AFTL-SASGELGVTQSLDRETKERFVLMITATDSGSP-ALTGTGTINVIVDDVNDNVPTF 2364
F + +G + + + D +++ A D G P +L +N+ V++ N T
Sbjct: 755 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA-TL 813
Query: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIG 2403
++ +I T++ V++ +D K V + G
Sbjct: 814 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAG 852
Score = 295 bits (755), Expect = 8e-79
Identities = 213/679 (31%), Positives = 336/679 (49%), Gaps = 47/679 (6%)
Query: 954 PLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNS 1013
P D H Y++E+ + +L V + + D+NDN+P+F +++ E+ +NS
Sbjct: 133 PRDEHC-FYEVEVAILPDEIFRL---VKIRFLIEDINDNAPLFPATVINISIPENSAINS 188
Query: 1014 RFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI----FPDG----QLYIKSELDRELQDR 1065
++ A D D G NG Y + + + FG+ P+G QL ++ ELDRE +D
Sbjct: 189 KYTLPAAVDPDVGINGVQNYELIKSQ--NIFGLDVIETPEGDKMPQLIVQKELDREEKDT 246
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAV 1125
YV+ V D S+T + V + D NDN P+F T E G+ V ++ A
Sbjct: 247 YVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHAT 306
Query: 1126 DKDFGPNGEVRYSFEMVQPD-----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
D D G N ++ +SF + + F L+A +G IT DRE T V+
Sbjct: 307 DADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE------TPNHKLLVL 360
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAP----KFLKDFYQATI--SESAANLTQVLRVSA 1234
A+D G+ + +A V V + D+NDN P +++ + T+ SE+ T++ ++
Sbjct: 361 ASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITV 417
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
+D D +NG + R + S + LDYE+T Y++ + A D+G P
Sbjct: 418 TDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPP 477
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
LN + L I + DENDN P F +S + V + EN G + V+ATD+DSG NA++ Y +
Sbjct: 478 LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-L 536
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFN 1414
G + FS+ TG + + KKLD E + Y I AKD G PP +S ++V + + D N
Sbjct: 537 LGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQN 596
Query: 1415 DNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEV 1474
DN P F + + EN+P +V +T DPD N ++ +I+ + + FTID
Sbjct: 597 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE---NDDFTIDSQ 653
Query: 1475 KGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI---- 1530
G I N DRE + VKA D R + VTI V D+NDN P+FI
Sbjct: 654 TGVIRPNISFDREKQESYTFYVKAEDGG---RVSRSSSAKVTINVVDVNDNKPVFIVPPY 710
Query: 1531 SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASA 1589
+ + PS G+V+ ++A D D G N E+ Y I+ G+T D F +D+ +G++ +
Sbjct: 711 NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEK 770
Query: 1590 LVPSQL-IYNLIVSATDLG 1607
+ L ++ ++V A DLG
Sbjct: 771 CDVTDLGLHRVLVKANDLG 789
Score = 278 bits (712), Expect = 7e-74
Identities = 218/680 (32%), Positives = 331/680 (48%), Gaps = 50/680 (7%)
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ 404
D+NDN P+ FPAT S+ EN+ + + L D D NG + +++
Sbjct: 163 DINDNAPL-----FPATVINISIPENSAINSKYTLPAAVDPDV-GINGVQNYELIKSQNI 216
Query: 405 RHFEV----QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVAS 460
+V + K+P L + K LDRE +Y + V V D G P RSS A
Sbjct: 217 FGLDVIETPEGDKMPQLIVQK---ELDREEKDTYVMKVKVEDG-GFPQ------RSSTAI 266
Query: 461 LVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYS---IVSG 517
L + V D ND+ PVF + V++ E AP G+ V+ + ATD D G NA + +S +VS
Sbjct: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
Query: 518 NGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVND 577
FH++ +GL+T LDRE L + A D G+ P + A ++V + DVND
Sbjct: 327 IARRLFHLNATTGLITIKEP--LDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVND 382
Query: 578 EKPVFS-----QPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR-S 631
P P V + EN P T++ ++ TD D NG V TD
Sbjct: 383 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-----CFTDHEIP 437
Query: 632 FRLDPVSGR---LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPV 688
FRL PV L + LD E Y++ +LA D G PP + A + + + D NDN+PV
Sbjct: 438 FRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPV 497
Query: 689 FYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTR 748
F I EN G + VSATD D G N + Y + F ++ ++G+++
Sbjct: 498 FTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVV 557
Query: 749 MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVAL 808
LDRE++ Y I+A D G + V ++++D DN PVF+ Y F V EN+
Sbjct: 558 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR 617
Query: 809 GYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA 868
VG ++ + D N + ++ D+ F I+ TG + DRE+Q Y V A
Sbjct: 618 HGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKA 677
Query: 869 -SGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDE 922
GG V + V I V D+NDN P F+ + + V+ + G +FQ AVD D
Sbjct: 678 EDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDT 737
Query: 923 GVNGMVLYSL-KQNPKNLFAINEKNGTISLLGPLDV-HAGSYQIEILASDMGVP-QLSSS 979
G+N V YS+ N ++LFAI+++ G I+L+ DV G +++ + A+D+G P L S
Sbjct: 738 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 797
Query: 980 VILTVYVHDVNDNSPVFDQL 999
VI+ ++V++ N+ + ++L
Sbjct: 798 VIVNLFVNESVTNATLINEL 817
Score = 278 bits (711), Expect = 1e-73
Identities = 213/704 (30%), Positives = 317/704 (45%), Gaps = 41/704 (5%)
Query: 613 GDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSM 672
GD +R E R+D R + + R+E FY + V P
Sbjct: 102 GDVPLIRIEEDTGEIFTTGARID----REKLCAGIPRDEHCFYEVEVAIL-----PDEIF 152
Query: 673 ARINVSLL--DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISA 730
+ + L DINDN+P+F I EN S T +A DPD+G NG Y +
Sbjct: 153 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 212
Query: 731 G------DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVL 784
D + + + LDREEK Y +++ DGG Q + AI+ ++V
Sbjct: 213 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 272
Query: 785 DTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMF 839
DT DN PVF + + EN +G V + A+ D+ N + + + +F
Sbjct: 273 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 332
Query: 840 AINQVTGQLTTANVIDREEQSFYQLKVVAS-GGTVTGDTMVNITVKDLNDNSP-----HF 893
+N TG +T +DREE ++L V+AS GG + MV + V D+NDN P +
Sbjct: 333 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 392
Query: 894 LQAI-ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVL-YSLKQNPKNLFAINEKNGTISL 951
+ + ++V + EN I D D NG V ++ + P L + +
Sbjct: 393 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN 452
Query: 952 LGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEP 1010
LD + Y I++LA+D G P L+ S +L + V D NDN+PVF Q V++ E+
Sbjct: 453 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 512
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMV 1070
+ KV A+D DSG N EI Y + + G L + +LDRE +D+Y+ +
Sbjct: 513 PGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTI 572
Query: 1071 VASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG 1130
+A D V PL++ V V V + D NDN P+F Y FY E VG ++ D D+G
Sbjct: 573 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYG 632
Query: 1131 PNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
N V S DF + + +G I FDRE ++F V A D G
Sbjct: 633 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREK------QESYTFYVKAEDGG-RVSR 685
Query: 1191 KDQATVHVYMKDINDNAPKFLKDFYQAT---ISESAANLTQVLRVSASDVDEGNNGLIHY 1247
A V + + D+NDN P F+ Y + + S T V +V A D D G N + Y
Sbjct: 686 SSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRY 745
Query: 1248 SIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
SI+ GN FAID +G +TL+ K D + ++++A D G
Sbjct: 746 SIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLG 789
Score = 264 bits (674), Expect = 2e-69
Identities = 214/729 (29%), Positives = 342/729 (46%), Gaps = 56/729 (7%)
Query: 718 LGTNGTVKYSISAGDRSRFQVNAQSGVISTRMA----------LDREEKTAYQLQIVATD 767
L T K GD ++ +G I T A + R+E Y++++
Sbjct: 89 LTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAI-- 146
Query: 768 GGNLQSPNQAIVTITVL--DTQDNPPVFSQVAYSFVVFENVALG--YHVGSVSASTMDLN 823
L +V I L D DN P+F + + EN A+ Y + + + +N
Sbjct: 147 ---LPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGIN 203
Query: 824 SNISY-LITTGDQKGMFAINQVTG----QLTTANVIDREEQSFYQLKVVASGGTV---TG 875
+Y LI + + G+ I G QL +DREE+ Y +KV G +
Sbjct: 204 GVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSS 263
Query: 876 DTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQN 935
++ ++V D NDN P F + V++ EN G S+ Q A D D G N + +S
Sbjct: 264 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 323
Query: 936 PKN----LFAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVN 990
N LF +N G I++ PLD ++++ +LASD G+ + + ++ V V DVN
Sbjct: 324 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVN 381
Query: 991 DNSPVFD------QLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAF 1044
DN P D ++ V LSE+ P+N++ + +DKD+ NG +
Sbjct: 382 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 1045 GIFPDGQLYIKSE-LDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNST 1103
+F + L + LD E Y + ++A+D PL+ + + + ++D NDN P+F +
Sbjct: 442 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 501
Query: 1104 NYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM-VQPDFELHAISGEITNTHQFD 1162
T E G + KVSA D D GPN E+ Y P+F L +G +T + D
Sbjct: 502 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 561
Query: 1163 RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISES 1222
RE + + FT++A D G+P PL TV V + D NDN+P F + Y+ + E+
Sbjct: 562 REKEDK------YLFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPEN 614
Query: 1223 AANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYS 1282
V ++ +D D G+N + SI+ N++ F IDS +G + D E +Y+
Sbjct: 615 LPRHGTVGLITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYT 672
Query: 1283 LVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF---PKSTLFVDVLENMRIGELVSSVTA 1339
++A D G + +S+ + I+++D NDN P F P + + VL + G +V V A
Sbjct: 673 FYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIA 732
Query: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPP 1399
D+D+G NA++ YSI G N F+I TG+I L +K D L+++ + A D G+P
Sbjct: 733 VDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP- 791
Query: 1400 RSSTMSVVI 1408
S SVVI
Sbjct: 792 -DSLFSVVI 799
Score = 250 bits (638), Expect = 3e-65
Identities = 233/805 (28%), Positives = 367/805 (45%), Gaps = 72/805 (8%)
Query: 1425 IFKSIVENIPIGTSVISVTAH-DPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTN-A 1482
I + I EN+ IG + + P+ + + + ++ + I+E G I+T A
Sbjct: 62 IREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGA 121
Query: 1483 EIDREFAN---------LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQN 1533
IDRE +E+ V + + L + L+ D+NDN P+F +
Sbjct: 122 RIDREKLCAGIPRDEHCFYEVEVAILPDEI------FRLVKIRFLIEDINDNAPLFPATV 175
Query: 1534 ALAADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASAL 1590
+ P ++ I S T A DPD G NG YE+I +++ GD ++ +
Sbjct: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGD-KMPQLI 234
Query: 1591 VPSQL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGE 1642
V +L Y + V D G +R ST L + + + PVF + + + E
Sbjct: 235 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENA 294
Query: 1643 PIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQG 1701
P+GT+V + A + G A + + ++ RLF + TG+I LDRE+
Sbjct: 295 PVGTSVTQLHATDADIGENAKIHFSFSNL--VSNIARRLFHLNATTGLITIKEPLDREET 352
Query: 1702 ACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGD 1755
L+ + S RA V + + D+NDN P + + + ENI
Sbjct: 353 PNHKLL----VLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPL 408
Query: 1756 GSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGD---LIATRRLDRERRSKYSL 1812
+KI +T D D N V T + + FR+ P + L LD E +Y++
Sbjct: 409 NTKIALITVTDKDADHNGRV--TCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAI 466
Query: 1813 -LVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD 1868
L+ AD G L S M + I V D ND+ P F++ + IPE+ PG + + ATD
Sbjct: 467 KLLAADAGKPPLNQSAM-LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDA 525
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT- 1927
DSG N EI Y++ D F L+ TG+ + + LD E + Y+ T+ A+D G T
Sbjct: 526 DSGPNAEINYLLGPDAPPE-FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTS 584
Query: 1928 -IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
+ V+ +I+D NDN P+F+ N Y + ENLP TV + VTD D G NS +T SI
Sbjct: 585 NVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-- 642
Query: 1987 DSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
D FT+D + GV++ + DRE Q Y V+ D ++ S S+A+V+I ++DVN
Sbjct: 643 DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRS---SSAKVTINVVDVN 699
Query: 2046 DNPPTFLSPKLTY-----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
DN P F+ P Y +P P TVVF+ A D D+G N+ + Y+++ GN +
Sbjct: 700 DNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLF 756
Query: 2101 TID---GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
ID G + L + D ++ + + V A D GQP S +V + ++ + N
Sbjct: 757 AIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINE 816
Query: 2158 LYKVEINENTLTGTDIIQVFAADGD 2182
L + I T+I V + D
Sbjct: 817 LVRKSIEAPVTPNTEIADVSSPTSD 841
Score = 249 bits (637), Expect = 4e-65
Identities = 217/719 (30%), Positives = 323/719 (44%), Gaps = 67/719 (9%)
Query: 2203 RIDSVTGAI-TVAKPLDREKT----PTYHLTVQATDRGSTPRTDTSTVSIVLL--DINDF 2255
RI+ TG I T +DREK P + P V I L DIND
Sbjct: 108 RIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDN 167
Query: 2256 VPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA--- 2312
P+F + ++++PEN + L A D D G N +Y L N F L
Sbjct: 168 APLFPATVINISIPENSAINSKYTLPA-AVDPDVGINGVQNYELI--KSQNIFGLDVIET 224
Query: 2313 -----SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASK 2367
+L V + LDRE K+ +V+ + D G P + T + V V D NDN P F
Sbjct: 225 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 284
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN-------SQFTINPSTGQIITS 2420
+IPE+AP GT V ++A+DAD +NA I N F +N +TG I
Sbjct: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
Query: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYV-----THI 2475
LDRE N+ L+V+ SD G + + VLV VTDVNDN P V T +
Sbjct: 345 EPLDREETPNHKLLVLASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVV 401
Query: 2476 PSPTLP-GSFVFAVTVTDADIGPNS--------ELHYSLSGRNSEKFHIDPLRGAIMAAG 2526
S +P + + +TVTD D N E+ + L S +F ++ A
Sbjct: 402 LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN-----AAYL 456
Query: 2527 PLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSSL 2585
E + D G P S + ++ ++ D P T PEN
Sbjct: 457 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
Query: 2586 VTTITGSSLRGEPMS--YYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARD 2643
+ ++ + P + Y+ + F +D+ TG +++ + LD EK KY+ I A+D
Sbjct: 517 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 576
Query: 2644 GGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR--KILTVSAMDKDSGPNG 2701
G PP +S + ++++D NDN+P+F + + + ENL PR + ++ D D G N
Sbjct: 577 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENL-PRHGTVGLITVTDPDYGDNS 635
Query: 2702 QLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMI 2761
+ I++ N + F+I+ TG IR DREK Y +K+ D G S+S+S KV I
Sbjct: 636 AVTLSILDEN--DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
Query: 2762 NILDENDNAPRF-----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL 2816
N++D NDN P F + + +P +P G V +V D D G+NA RYSI+ +
Sbjct: 694 NVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNT 752
Query: 2817 P--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVS----TDVTIFVTDINDNA 2869
F I+ TG+I + + D +R+ V A+D G S V +FV + NA
Sbjct: 753 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA 811
Score = 236 bits (603), Expect = 3e-61
Identities = 209/719 (29%), Positives = 335/719 (46%), Gaps = 68/719 (9%)
Query: 2410 INPSTGQIITS-ALLDRET------KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
I TG+I T+ A +DRE +D + V A P+ + + + D+NDN
Sbjct: 109 IEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEV-EVAILPDEIFRLVKIRFLIEDINDN 167
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGA- 2521
P F IP + S D D+G N +Y L ++ F +D +
Sbjct: 168 APLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELI-KSQNIFGLDVIETPE 226
Query: 2522 ------IMAAGPLNGASEVTFSVHVK-DGGSFPKTDSTTVTVRFVNKAD--FPKVRAKEQ 2572
++ L+ + T+ + VK + G FP+ ST + V + P + E
Sbjct: 227 GDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 286
Query: 2573 TFMFPENQPVSSLVTTITGSSLR-GEPMSYYIASGNLGNT-----FQIDQLTGQVSISQP 2626
PEN PV + VT + + GE + + NL + F ++ TG ++I +P
Sbjct: 287 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 346
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEI------LE 2680
LD E+ + + + A DGG P + +++T DVNDN P ++ + E
Sbjct: 347 LDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSE 404
Query: 2681 NLSPR-KILTVSAMDKDSGPNGQL----DYEI---VNGNMENSFSINHATGEIRSVRPLD 2732
N+ KI ++ DKD+ NG++ D+EI + N F + +A LD
Sbjct: 405 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY-------LD 457
Query: 2733 REKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIF-SAHVPENSPLGYTV 2791
E Y + + ++D G P + S + I + DENDNAP F+Q F + +PEN+ G +
Sbjct: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 517
Query: 2792 TRVTTSDEDIGINAISRYSI-MDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDS 2850
+V+ +D D G NA Y + DA F+++ TG + + + L+RE D+Y + A D+
Sbjct: 518 MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 577
Query: 2851 GWT-VSTDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQV 2907
G ++++VT+FV+ D NDN+P F+ Y PE V + TDPD G N V
Sbjct: 578 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 637
Query: 2908 FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET 2967
I +++ F I++ TG I N++ F ++F V + D G+ S S
Sbjct: 638 TLSILDENDDFTIDSQTGVI-------RPNIS-FDREKQESYTFYVKAEDGGRVSRSSSA 689
Query: 2968 TVTINIVDSNDNAPQFLKSKY---FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFIS 3024
VTIN+VD NDN P F+ Y + V + GT + +V A+D+ D G+N+EV Y I
Sbjct: 690 KVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDN-DTGMNAEVRYSIV 748
Query: 3025 NDNHLGKFKLDNDTGWISVASSL-ISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTE 3081
N F +D +TG I++ ++DL + + V A D G P L S V++ V E
Sbjct: 749 GGNTRDLFAIDQETGNITLMEKCDVTDLGLH-RVLVKANDLGQPDSLFSVVIVNLFVNE 806
Score = 220 bits (560), Expect = 3e-56
Identities = 187/661 (28%), Positives = 306/661 (46%), Gaps = 38/661 (5%)
Query: 2858 VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG-QVFYFIKSQSE 2916
+ + DINDNAP F T + PE + I SK T A DPD G NG Q + IKSQ+
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 2917 YFRINATTGE-------IFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTV 2969
+ T E I K++ + + T V + D G P S +
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVE---------DGGFPQRSSTAIL 267
Query: 2970 TINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN-DNH 3028
+++ D+NDN P F +++ + +N VGT + ++ A D D G N+++ + SN ++
Sbjct: 268 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD-ADIGENAKIHFSFSNLVSN 326
Query: 3029 LGK--FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
+ + F L+ TG I++ L + N + V A D G P ++A V + VT+ N +
Sbjct: 327 IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNV 384
Query: 3087 PEFSQSHM------SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
P ++ + + E+ + + + ++ D+DA NG + + +
Sbjct: 385 PSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF 444
Query: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYF 3200
S+ +L A LDYE +++ + + A D G + + V D NDN+PVF
Sbjct: 445 SNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT 504
Query: 3201 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFET 3260
++ EN G ++ ++ATDADSG NA I Y + F +D TG++T LD E
Sbjct: 505 VSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREK 564
Query: 3261 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 3320
+ Y T+ A + S TV + + N+ P F Y F + E P+ VG +
Sbjct: 565 EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLI 624
Query: 3321 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGS 3380
+D D G + V I F I+ +TG I + DREK+E + V A++ G
Sbjct: 625 TVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGR 682
Query: 3381 IRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPI---GTHVTFVSAFDSDSIPS 3436
+ + +VT+N V+D ND P+F + Y+ +P GT V V A D+D+ +
Sbjct: 683 VSRSSSAKVTIN--VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 740
Query: 3437 WSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASL 3496
+ Y I GN F+I+ +TG IT+ + D L ++ + V A D G P + S +
Sbjct: 741 -AEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 799
Query: 3497 L 3497
+
Sbjct: 800 V 800
Score = 219 bits (558), Expect = 5e-56
Identities = 181/643 (28%), Positives = 290/643 (45%), Gaps = 31/643 (4%)
Query: 2919 RINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSND 2978
RI TGEIF + + + + H F + + I D ND
Sbjct: 108 RIEEDTGEIFTTGA-RIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIND 166
Query: 2979 NAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY-FISNDNHLGKFKLDND 3037
NAP F + + +N + +K A+D D G+N Y I + N G ++
Sbjct: 167 NAPLFPATVINISIPENSAINSKYTLPAAVDP-DVGINGVQNYELIKSQNIFGLDVIETP 225
Query: 3038 TG----WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSH 3093
G + V L + + + V +D G P SS A + ++VT+ N + P F ++
Sbjct: 226 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETE 285
Query: 3094 MSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS---SGNEEGIFAINSSTGILTLAK 3150
+ +IPE+ +G+ V + A D D N I +S S S +F +N++TG++T+ +
Sbjct: 286 IEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKE 345
Query: 3151 ALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL-- 3204
LD E H++ + A DGG + V VNV DVNDN P ++ + TV+
Sbjct: 346 PLDREETPNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 403
Query: 3205 ENAPSGTTVIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQS 3263
EN P T + + TD D+ N V +T L + N ++ +LD+E+ +
Sbjct: 404 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKE 463
Query: 3264 YHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFAS 3323
Y + + A + A + I++K N+ P F I E G + +V A+
Sbjct: 464 YAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSAT 523
Query: 3324 DRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRG 3383
D D G + E++YL+ G F ++++TG + V LDREKE++ +LAK+ G
Sbjct: 524 DADSGPNAEINYLL-GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGV--P 580
Query: 3384 ADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY 3442
VTV V+++D ND P+FT N Y + E +P V ++ D D +
Sbjct: 581 PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY---GDNSAV 637
Query: 3443 FIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLED 3502
+ +EN F+I+ QTG I DRE Y V A D G S + SA + + + D
Sbjct: 638 TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVD 697
Query: 3503 INDNGPMLTV-----SEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
+NDN P+ V S V+ + PGT+V + + D D N
Sbjct: 698 VNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 740
Score = 186 bits (471), Expect = 7e-46
Identities = 165/558 (29%), Positives = 262/558 (46%), Gaps = 35/558 (6%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYS-ISSGNE 3133
+ + + N + P F + ++ +IPE+ +I S +A D D +NG+ Y I S N
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 3134 EGIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ I + G L + K LD E + M + DGG+ R+ + V+V D ND
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 276
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD----LFVIDP 3245
N PVF + ++ ENAP GT+V L+ATDAD G NA I ++ + S+ LF ++
Sbjct: 277 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 336
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
TG+IT + LD E ++ L V A + + VN+ N+ VP +
Sbjct: 337 TTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVN 394
Query: 3306 EI------SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
+ SE P T + + +D+D +G V + F++ ++
Sbjct: 395 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF---TDHEIPFRLRPVFSNQFLLE 451
Query: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
+ LD E + ++K+LA + G + + + V D ND P+FT + +V I E
Sbjct: 452 NAAYLDYESTKEYAIKLLAADAG--KPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPE 509
Query: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
G + VSA D+DS P+ + +Y +G + FS++ +TG +TV +LDRE
Sbjct: 510 NNSPGIQLMKVSATDADSGPN-AEINYLLGP-DAPPEFSLDRRTGMLTVVKKLDREKEDK 567
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
Y ++LA D+G P T + ++ V++ D NDN P+ T +E + V EN V + T
Sbjct: 568 YLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVT 627
Query: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSL-STAGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
DPD N LS F++ S GV+ DRE+ + V +D G
Sbjct: 628 DPDYGDNSA----VTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRV 683
Query: 3593 QMSSTGTVHITVIDQNDN 3610
SS+ V I V+D NDN
Sbjct: 684 SRSSSAKVTINVVDVNDN 701
Score = 110 bits (275), Expect = 3e-23
Identities = 132/499 (26%), Positives = 210/499 (42%), Gaps = 41/499 (8%)
Query: 3234 QSSDSDLFVIDPNTGVITTQGF-LDFET-------KQSYHLTVKAFNVPDEERCSFATVN 3285
++ D L I+ +TG I T G +D E + V+ +PDE F V
Sbjct: 100 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDE---IFRLVK 156
Query: 3286 IQ--LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
I+ ++ N+ P F + + I E + + A D D+G +G +Y + +
Sbjct: 157 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 216
Query: 3344 KGFQI-----NKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDA 3398
G + K Q+ V LDRE+++ +KV ++ G + + + V+VT D
Sbjct: 217 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT--DT 274
Query: 3399 NDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FS 3454
ND P+F V I E P+GT VT + A D+D I ++ + + N A F
Sbjct: 275 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFH 333
Query: 3455 INPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--- 3511
+N TG IT+ LDRE P + L VLA D G A A +LV + D+NDN P +
Sbjct: 334 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR--AMVLVNVTDVNDNVPSIDIRY 391
Query: 3512 ----VSEGEVMENKRP-GTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVL 3566
V++ V+ P T + + TD D N G T + P S +L
Sbjct: 392 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHN-GRVTCFTDHEIPFRLRPVFSNQFLL 450
Query: 3567 STTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGN 3626
+D E ++ + ++ D+G P ++ + + I V D+NDN + V+ N
Sbjct: 451 ENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN 510
Query: 3627 LFPGGILGSVKPQDPDVLDSFHCSLTSGVT-----SLFSIPGGTCDLNSQPRSTDGTFDL 3681
PG L V D D + + G SL G + R + +
Sbjct: 511 NSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF 570
Query: 3682 TVLSNDGVHSTVTSNIRVF 3700
T+L+ D +TSN+ VF
Sbjct: 571 TILAKDNGVPPLTSNVTVF 589
Score = 34.7 bits (78), Expect = 2.4
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 27/161 (16%)
Query: 4505 VPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPDNIPP 4564
V A+ G+ V+ + + +++ C Q KA +K +N + P+ P
Sbjct: 847 VAAVAGTITVVVVIFITAVVRCRQAPHLKAA------------QKNMQNSEWATPN---P 891
Query: 4565 YGDDMTV----RKQPEGNPKP---DIIERENPYLIYDETDIPHNSETIPSAPLASPEQEI 4617
M + +K+ + +PK +++ E D+ D N T+ P+ EQ +
Sbjct: 892 ENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKA--DDVDSDGNRVTL-DLPIDLEEQTM 948
Query: 4618 EHYD-IDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPL 4657
Y+ + ++ P D+ +HYK S P F IQ +PL
Sbjct: 949 GKYNWVTTPTTFKPDSPDLARHYKS-ASPQPAFQIQPETPL 988
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 329 bits (843), Expect = 5e-89
Identities = 246/764 (32%), Positives = 380/764 (49%), Gaps = 50/764 (6%)
Query: 80 LFAINSSTGALYTTST-IDRESLPSDV---------INLVVLSSAPTYPTEVRVLVRDLN 129
L I TG ++TT IDRE L + + + + +L ++R L+ D+N
Sbjct: 95 LIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN 154
Query: 130 DNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAGRFRLDI 189
DNAP+FP I ++ E+S+ + L A D D+G NGV ++Y +I+ F LD+
Sbjct: 155 DNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGV--QNYELIKSQNI--FGLDV 210
Query: 190 TLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPV 249
P G+ L+ + LDRE Y + V+VED G P+R + V+V D NDN PV
Sbjct: 211 IETPEGD-KMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV 269
Query: 250 FGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD-----EGTPFQMDPETGL 304
F + + +PE+A VG+SV Q+ A DAD G NA I + + F ++ TGL
Sbjct: 270 FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL 329
Query: 305 ITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYF-PATSR 363
IT++EPLD E + L V A D G+ + RA L+ + DVNDN P + RY +
Sbjct: 330 ITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVND 387
Query: 364 YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVA 423
+ EN + T +AL+TVTD D+ NG ++ + + F ++ N L++ A
Sbjct: 388 TVVLSENIPLNTKIALITVTDKDAD-HNGRVTCFT---DHEIPFRLR-PVFSNQFLLENA 442
Query: 424 SALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVN 483
+ LD E Y + + +D G PP + A L I V D ND+ PVF+Q V+
Sbjct: 443 AYLDYESTKEYAIKLLAAD-AGKPP------LNQSAMLFIKVKDENDNAPVFTQSFVTVS 495
Query: 484 LSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRE 543
+ E PG + +SATD DSG NA + Y ++ + F + +G++T LDRE
Sbjct: 496 IPENNSPGIQLMKVSATDADSGPNAEINY-LLGPDAPPEFSLDRRTGMLTVVKK--LDRE 552
Query: 544 LASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELL 603
+ + I A+D GV P S + V+++D ND PVF+ E Y V EN P +
Sbjct: 553 KEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNE-YKFYVPENLPRHGTVG 611
Query: 604 MLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATD 663
++ TD D GDN V S+ + D F +D +G + S DRE+Q Y+ V A D
Sbjct: 612 LITVTDPDYGDNSAVTLSILDENDD---FTIDSQTGVIRPNISFDREKQESYTFYVKAED 668
Query: 664 LGSPPQSSMARINVSLLDINDNSPVF----YPVQYFAHIKENEPGGSYITTVSATDPDLG 719
G +SS A++ ++++D+NDN PVF Y Y + P G+ + V A D D G
Sbjct: 669 GGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTG 727
Query: 720 TNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSP-NQA 777
N V+YSI G+ R F ++ ++G I+ D + +++ + A D G S +
Sbjct: 728 MNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVV 787
Query: 778 IVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMD 821
IV + V ++ N + +++ + V + VS+ T D
Sbjct: 788 IVNLFVNESVTNATLINELVRKSIE-APVTPNTEIADVSSPTSD 830
Score = 298 bits (763), Expect = 9e-80
Identities = 233/759 (30%), Positives = 365/759 (48%), Gaps = 38/759 (5%)
Query: 1670 VRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEIT 1729
+R EE T G +FT G + A + R++ C Y V+V AI F + ++
Sbjct: 96 IRIEEDT-GEIFTTGARIDREKLCAGIPRDEH-CFYEVEV-AILPDEIF---RLVKIRFL 149
Query: 1730 LQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRI 1789
++DINDN P+FP ++++++ EN SK A+D D G N + Y +I + + F +
Sbjct: 150 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK-SQNIFGL 208
Query: 1790 D----PESG---DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTP 1839
D PE LI + LDRE + Y + V+ +DG +SS + ++V+D ND+ P
Sbjct: 209 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 268
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE---DDEDGIFFLNPITG 1896
F IPE+ G+ V + ATD D G N +I + + + +F LN TG
Sbjct: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
Query: 1897 VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLN------SYS 1950
+ + LD E + L V A DGG V N+ DVNDN P + + +
Sbjct: 329 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 388
Query: 1951 TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKA-LDRE 2009
L EN+P+ + + + VTD D N ++T V N L A LD E
Sbjct: 389 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 448
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTV 2068
S Y + + D + P ++ +A + I + D NDN P F +T IPEN
Sbjct: 449 STKEYAIKLLAADAGKPPLNQ---SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 505
Query: 2069 VFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
+ K ATD DSGPN+ I Y L +FS+ G + + +LDRE+ Y T++A D
Sbjct: 506 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 565
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P L+S+ V V ++D NDN+P+F YK + EN + + D D G N
Sbjct: 566 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSA 625
Query: 2189 VRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIV 2248
V I+ + N +F IDS TG I DREK +Y V+A D G R+ ++ V+I
Sbjct: 626 VTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
Query: 2249 LLDINDFVPVFELSPYSVNVPENL-GTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDN 2306
++D+ND PVF + PY+ + L T P T++ QV+A D+D G N+++ Y + GGN +
Sbjct: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
Query: 2307 AFTL-SASGELGVTQSLDRETKERFVLMITATDSGSP-ALTGTGTINVIVDDVNDNVPTF 2364
F + +G + + + D +++ A D G P +L +N+ V++ N T
Sbjct: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA-TL 802
Query: 2365 ASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIG 2403
++ +I T++ V++ +D K V + G
Sbjct: 803 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAG 841
Score = 295 bits (755), Expect = 8e-79
Identities = 213/679 (31%), Positives = 336/679 (49%), Gaps = 47/679 (6%)
Query: 954 PLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNS 1013
P D H Y++E+ + +L V + + D+NDN+P+F +++ E+ +NS
Sbjct: 122 PRDEHC-FYEVEVAILPDEIFRL---VKIRFLIEDINDNAPLFPATVINISIPENSAINS 177
Query: 1014 RFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI----FPDG----QLYIKSELDRELQDR 1065
++ A D D G NG Y + + + FG+ P+G QL ++ ELDRE +D
Sbjct: 178 KYTLPAAVDPDVGINGVQNYELIKSQ--NIFGLDVIETPEGDKMPQLIVQKELDREEKDT 235
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAV 1125
YV+ V D S+T + V + D NDN P+F T E G+ V ++ A
Sbjct: 236 YVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHAT 295
Query: 1126 DKDFGPNGEVRYSFEMVQPD-----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
D D G N ++ +SF + + F L+A +G IT DRE T V+
Sbjct: 296 DADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE------TPNHKLLVL 349
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAP----KFLKDFYQATI--SESAANLTQVLRVSA 1234
A+D G+ + +A V V + D+NDN P +++ + T+ SE+ T++ ++
Sbjct: 350 ASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITV 406
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
+D D +NG + R + S + LDYE+T Y++ + A D+G P
Sbjct: 407 TDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPP 466
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
LN + L I + DENDN P F +S + V + EN G + V+ATD+DSG NA++ Y +
Sbjct: 467 LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY-L 525
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFN 1414
G + FS+ TG + + KKLD E + Y I AKD G PP +S ++V + + D N
Sbjct: 526 LGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQN 585
Query: 1415 DNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEV 1474
DN P F + + EN+P +V +T DPD N ++ +I+ + + FTID
Sbjct: 586 DNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE---NDDFTIDSQ 642
Query: 1475 KGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFI---- 1530
G I N DRE + VKA D R + VTI V D+NDN P+FI
Sbjct: 643 TGVIRPNISFDREKQESYTFYVKAEDGG---RVSRSSSAKVTINVVDVNDNKPVFIVPPY 699
Query: 1531 SQNALAADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASA 1589
+ + PS G+V+ ++A D D G N E+ Y I+ G+T D F +D+ +G++ +
Sbjct: 700 NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEK 759
Query: 1590 LVPSQL-IYNLIVSATDLG 1607
+ L ++ ++V A DLG
Sbjct: 760 CDVTDLGLHRVLVKANDLG 778
Score = 278 bits (712), Expect = 7e-74
Identities = 218/680 (32%), Positives = 331/680 (48%), Gaps = 50/680 (7%)
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ 404
D+NDN P+ FPAT S+ EN+ + + L D D NG + +++
Sbjct: 152 DINDNAPL-----FPATVINISIPENSAINSKYTLPAAVDPDV-GINGVQNYELIKSQNI 205
Query: 405 RHFEV----QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVAS 460
+V + K+P L + K LDRE +Y + V V D G P RSS A
Sbjct: 206 FGLDVIETPEGDKMPQLIVQK---ELDREEKDTYVMKVKVEDG-GFPQ------RSSTAI 255
Query: 461 LVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYS---IVSG 517
L + V D ND+ PVF + V++ E AP G+ V+ + ATD D G NA + +S +VS
Sbjct: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 315
Query: 518 NGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVND 577
FH++ +GL+T LDRE L + A D G+ P + A ++V + DVND
Sbjct: 316 IARRLFHLNATTGLITIKEP--LDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVND 371
Query: 578 EKPVFS-----QPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR-S 631
P P V + EN P T++ ++ TD D NG V TD
Sbjct: 372 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-----CFTDHEIP 426
Query: 632 FRLDPVSGR---LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPV 688
FRL PV L + LD E Y++ +LA D G PP + A + + + D NDN+PV
Sbjct: 427 FRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPV 486
Query: 689 FYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTR 748
F I EN G + VSATD D G N + Y + F ++ ++G+++
Sbjct: 487 FTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVV 546
Query: 749 MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVAL 808
LDRE++ Y I+A D G + V ++++D DN PVF+ Y F V EN+
Sbjct: 547 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPR 606
Query: 809 GYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA 868
VG ++ + D N + ++ D+ F I+ TG + DRE+Q Y V A
Sbjct: 607 HGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKA 666
Query: 869 -SGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDE 922
GG V + V I V D+NDN P F+ + + V+ + G +FQ AVD D
Sbjct: 667 EDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDT 726
Query: 923 GVNGMVLYSL-KQNPKNLFAINEKNGTISLLGPLDV-HAGSYQIEILASDMGVP-QLSSS 979
G+N V YS+ N ++LFAI+++ G I+L+ DV G +++ + A+D+G P L S
Sbjct: 727 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 786
Query: 980 VILTVYVHDVNDNSPVFDQL 999
VI+ ++V++ N+ + ++L
Sbjct: 787 VIVNLFVNESVTNATLINEL 806
Score = 278 bits (711), Expect = 1e-73
Identities = 213/704 (30%), Positives = 317/704 (45%), Gaps = 41/704 (5%)
Query: 613 GDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSM 672
GD +R E R+D R + + R+E FY + V P
Sbjct: 91 GDVPLIRIEEDTGEIFTTGARID----REKLCAGIPRDEHCFYEVEVAIL-----PDEIF 141
Query: 673 ARINVSLL--DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISA 730
+ + L DINDN+P+F I EN S T +A DPD+G NG Y +
Sbjct: 142 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 201
Query: 731 G------DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVL 784
D + + + LDREEK Y +++ DGG Q + AI+ ++V
Sbjct: 202 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 261
Query: 785 DTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMF 839
DT DN PVF + + EN +G V + A+ D+ N + + + +F
Sbjct: 262 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 321
Query: 840 AINQVTGQLTTANVIDREEQSFYQLKVVAS-GGTVTGDTMVNITVKDLNDNSP-----HF 893
+N TG +T +DREE ++L V+AS GG + MV + V D+NDN P +
Sbjct: 322 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 381
Query: 894 LQAI-ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVL-YSLKQNPKNLFAINEKNGTISL 951
+ + ++V + EN I D D NG V ++ + P L + +
Sbjct: 382 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN 441
Query: 952 LGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEP 1010
LD + Y I++LA+D G P L+ S +L + V D NDN+PVF Q V++ E+
Sbjct: 442 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 501
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMV 1070
+ KV A+D DSG N EI Y + + G L + +LDRE +D+Y+ +
Sbjct: 502 PGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTI 561
Query: 1071 VASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG 1130
+A D V PL++ V V V + D NDN P+F Y FY E VG ++ D D+G
Sbjct: 562 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYG 621
Query: 1131 PNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
N V S DF + + +G I FDRE ++F V A D G
Sbjct: 622 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREK------QESYTFYVKAEDGG-RVSR 674
Query: 1191 KDQATVHVYMKDINDNAPKFLKDFYQAT---ISESAANLTQVLRVSASDVDEGNNGLIHY 1247
A V + + D+NDN P F+ Y + + S T V +V A D D G N + Y
Sbjct: 675 SSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRY 734
Query: 1248 SIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
SI+ GN FAID +G +TL+ K D + ++++A D G
Sbjct: 735 SIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLG 778
Score = 264 bits (674), Expect = 2e-69
Identities = 214/729 (29%), Positives = 342/729 (46%), Gaps = 56/729 (7%)
Query: 718 LGTNGTVKYSISAGDRSRFQVNAQSGVISTRMA----------LDREEKTAYQLQIVATD 767
L T K GD ++ +G I T A + R+E Y++++
Sbjct: 78 LTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAI-- 135
Query: 768 GGNLQSPNQAIVTITVL--DTQDNPPVFSQVAYSFVVFENVALG--YHVGSVSASTMDLN 823
L +V I L D DN P+F + + EN A+ Y + + + +N
Sbjct: 136 ---LPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGIN 192
Query: 824 SNISY-LITTGDQKGMFAINQVTG----QLTTANVIDREEQSFYQLKVVASGGTV---TG 875
+Y LI + + G+ I G QL +DREE+ Y +KV G +
Sbjct: 193 GVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSS 252
Query: 876 DTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQN 935
++ ++V D NDN P F + V++ EN G S+ Q A D D G N + +S
Sbjct: 253 TAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNL 312
Query: 936 PKN----LFAINEKNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVN 990
N LF +N G I++ PLD ++++ +LASD G+ + + ++ V V DVN
Sbjct: 313 VSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVN 370
Query: 991 DNSPVFD------QLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAF 1044
DN P D ++ V LSE+ P+N++ + +DKD+ NG +
Sbjct: 371 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
Query: 1045 GIFPDGQLYIKSE-LDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNST 1103
+F + L + LD E Y + ++A+D PL+ + + + ++D NDN P+F +
Sbjct: 431 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 490
Query: 1104 NYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEM-VQPDFELHAISGEITNTHQFD 1162
T E G + KVSA D D GPN E+ Y P+F L +G +T + D
Sbjct: 491 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 550
Query: 1163 RESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISES 1222
RE + + FT++A D G+P PL TV V + D NDN+P F + Y+ + E+
Sbjct: 551 REKEDK------YLFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPEN 603
Query: 1223 AANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYS 1282
V ++ +D D G+N + SI+ N++ F IDS +G + D E +Y+
Sbjct: 604 LPRHGTVGLITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYT 661
Query: 1283 LVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF---PKSTLFVDVLENMRIGELVSSVTA 1339
++A D G + +S+ + I+++D NDN P F P + + VL + G +V V A
Sbjct: 662 FYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIA 721
Query: 1340 TDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPP 1399
D+D+G NA++ YSI G N F+I TG+I L +K D L+++ + A D G+P
Sbjct: 722 VDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP- 780
Query: 1400 RSSTMSVVI 1408
S SVVI
Sbjct: 781 -DSLFSVVI 788
Score = 250 bits (638), Expect = 3e-65
Identities = 233/805 (28%), Positives = 367/805 (45%), Gaps = 72/805 (8%)
Query: 1425 IFKSIVENIPIGTSVISVTAH-DPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTN-A 1482
I + I EN+ IG + + P+ + + + ++ + I+E G I+T A
Sbjct: 51 IREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGA 110
Query: 1483 EIDREFAN---------LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQN 1533
IDRE +E+ V + + L + L+ D+NDN P+F +
Sbjct: 111 RIDREKLCAGIPRDEHCFYEVEVAILPDEI------FRLVKIRFLIEDINDNAPLFPATV 164
Query: 1534 ALAADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASAL 1590
+ P ++ I S T A DPD G NG YE+I +++ GD ++ +
Sbjct: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGD-KMPQLI 223
Query: 1591 VPSQL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGE 1642
V +L Y + V D G +R ST L + + + PVF + + + E
Sbjct: 224 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENA 283
Query: 1643 PIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQG 1701
P+GT+V + A + G A + + ++ RLF + TG+I LDRE+
Sbjct: 284 PVGTSVTQLHATDADIGENAKIHFSFSNL--VSNIARRLFHLNATTGLITIKEPLDREET 341
Query: 1702 ACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGD 1755
L+ + S RA V + + D+NDN P + + + ENI
Sbjct: 342 PNHKLL----VLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPL 397
Query: 1756 GSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGD---LIATRRLDRERRSKYSL 1812
+KI +T D D N V T + + FR+ P + L LD E +Y++
Sbjct: 398 NTKIALITVTDKDADHNGRV--TCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAI 455
Query: 1813 -LVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD 1868
L+ AD G L S M + I V D ND+ P F++ + IPE+ PG + + ATD
Sbjct: 456 KLLAADAGKPPLNQSAM-LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDA 514
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT- 1927
DSG N EI Y++ D F L+ TG+ + + LD E + Y+ T+ A+D G T
Sbjct: 515 DSGPNAEINYLLGPDAPPE-FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTS 573
Query: 1928 -IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
+ V+ +I+D NDN P+F+ N Y + ENLP TV + VTD D G NS +T SI
Sbjct: 574 NVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-- 631
Query: 1987 DSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
D FT+D + GV++ + DRE Q Y V+ D ++ S S+A+V+I ++DVN
Sbjct: 632 DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRS---SSAKVTINVVDVN 688
Query: 2046 DNPPTFLSPKLTY-----IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
DN P F+ P Y +P P TVVF+ A D D+G N+ + Y+++ GN +
Sbjct: 689 DNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLF 745
Query: 2101 TID---GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
ID G + L + D ++ + + V A D GQP S +V + ++ + N
Sbjct: 746 AIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINE 805
Query: 2158 LYKVEINENTLTGTDIIQVFAADGD 2182
L + I T+I V + D
Sbjct: 806 LVRKSIEAPVTPNTEIADVSSPTSD 830
Score = 249 bits (637), Expect = 4e-65
Identities = 217/719 (30%), Positives = 323/719 (44%), Gaps = 67/719 (9%)
Query: 2203 RIDSVTGAI-TVAKPLDREKT----PTYHLTVQATDRGSTPRTDTSTVSIVLL--DINDF 2255
RI+ TG I T +DREK P + P V I L DIND
Sbjct: 97 RIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDN 156
Query: 2256 VPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA--- 2312
P+F + ++++PEN + L A D D G N +Y L N F L
Sbjct: 157 APLFPATVINISIPENSAINSKYTLPA-AVDPDVGINGVQNYELI--KSQNIFGLDVIET 213
Query: 2313 -----SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASK 2367
+L V + LDRE K+ +V+ + D G P + T + V V D NDN P F
Sbjct: 214 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 273
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN-------SQFTINPSTGQIITS 2420
+IPE+AP GT V ++A+DAD +NA I N F +N +TG I
Sbjct: 274 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 333
Query: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYV-----THI 2475
LDRE N+ L+V+ SD G + + VLV VTDVNDN P V T +
Sbjct: 334 EPLDREETPNHKLLVLASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVV 390
Query: 2476 PSPTLP-GSFVFAVTVTDADIGPNS--------ELHYSLSGRNSEKFHIDPLRGAIMAAG 2526
S +P + + +TVTD D N E+ + L S +F ++ A
Sbjct: 391 LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLEN-----AAYL 445
Query: 2527 PLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSSL 2585
E + D G P S + ++ ++ D P T PEN
Sbjct: 446 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 505
Query: 2586 VTTITGSSLRGEPMS--YYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARD 2643
+ ++ + P + Y+ + F +D+ TG +++ + LD EK KY+ I A+D
Sbjct: 506 LMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKD 565
Query: 2644 GGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR--KILTVSAMDKDSGPNG 2701
G PP +S + ++++D NDN+P+F + + + ENL PR + ++ D D G N
Sbjct: 566 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENL-PRHGTVGLITVTDPDYGDNS 624
Query: 2702 QLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMI 2761
+ I++ N + F+I+ TG IR DREK Y +K+ D G S+S+S KV I
Sbjct: 625 AVTLSILDEN--DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 682
Query: 2762 NILDENDNAPRF-----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL 2816
N++D NDN P F + + +P +P G V +V D D G+NA RYSI+ +
Sbjct: 683 NVVDVNDNKPVFIVPPYNYSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNT 741
Query: 2817 P--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVS----TDVTIFVTDINDNA 2869
F I+ TG+I + + D +R+ V A+D G S V +FV + NA
Sbjct: 742 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA 800
Score = 236 bits (603), Expect = 3e-61
Identities = 209/719 (29%), Positives = 335/719 (46%), Gaps = 68/719 (9%)
Query: 2410 INPSTGQIITS-ALLDRET------KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
I TG+I T+ A +DRE +D + V A P+ + + + D+NDN
Sbjct: 98 IEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEV-EVAILPDEIFRLVKIRFLIEDINDN 156
Query: 2463 PPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGA- 2521
P F IP + S D D+G N +Y L ++ F +D +
Sbjct: 157 APLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELI-KSQNIFGLDVIETPE 215
Query: 2522 ------IMAAGPLNGASEVTFSVHVK-DGGSFPKTDSTTVTVRFVNKAD--FPKVRAKEQ 2572
++ L+ + T+ + VK + G FP+ ST + V + P + E
Sbjct: 216 GDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 275
Query: 2573 TFMFPENQPVSSLVTTITGSSLR-GEPMSYYIASGNLGNT-----FQIDQLTGQVSISQP 2626
PEN PV + VT + + GE + + NL + F ++ TG ++I +P
Sbjct: 276 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 335
Query: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEI------LE 2680
LD E+ + + + A DGG P + +++T DVNDN P ++ + E
Sbjct: 336 LDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSE 393
Query: 2681 NLSPR-KILTVSAMDKDSGPNGQL----DYEI---VNGNMENSFSINHATGEIRSVRPLD 2732
N+ KI ++ DKD+ NG++ D+EI + N F + +A LD
Sbjct: 394 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY-------LD 446
Query: 2733 REKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIF-SAHVPENSPLGYTV 2791
E Y + + ++D G P + S + I + DENDNAP F+Q F + +PEN+ G +
Sbjct: 447 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 506
Query: 2792 TRVTTSDEDIGINAISRYSI-MDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDS 2850
+V+ +D D G NA Y + DA F+++ TG + + + L+RE D+Y + A D+
Sbjct: 507 MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 566
Query: 2851 GWT-VSTDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQV 2907
G ++++VT+FV+ D NDN+P F+ Y PE V + TDPD G N V
Sbjct: 567 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 626
Query: 2908 FYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISET 2967
I +++ F I++ TG I N++ F ++F V + D G+ S S
Sbjct: 627 TLSILDENDDFTIDSQTGVI-------RPNIS-FDREKQESYTFYVKAEDGGRVSRSSSA 678
Query: 2968 TVTINIVDSNDNAPQFLKSKY---FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFIS 3024
VTIN+VD NDN P F+ Y + V + GT + +V A+D+ D G+N+EV Y I
Sbjct: 679 KVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDN-DTGMNAEVRYSIV 737
Query: 3025 NDNHLGKFKLDNDTGWISVASSL-ISDLNQNFFITVTAKDKGNP-PLSSQATVHITVTE 3081
N F +D +TG I++ ++DL + + V A D G P L S V++ V E
Sbjct: 738 GGNTRDLFAIDQETGNITLMEKCDVTDLGLH-RVLVKANDLGQPDSLFSVVIVNLFVNE 795
Score = 220 bits (560), Expect = 3e-56
Identities = 187/661 (28%), Positives = 306/661 (46%), Gaps = 38/661 (5%)
Query: 2858 VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG-QVFYFIKSQSE 2916
+ + DINDNAP F T + PE + I SK T A DPD G NG Q + IKSQ+
Sbjct: 146 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 205
Query: 2917 YFRINATTGE-------IFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTV 2969
+ T E I K++ + + T V + D G P S +
Sbjct: 206 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVE---------DGGFPQRSSTAIL 256
Query: 2970 TINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN-DNH 3028
+++ D+NDN P F +++ + +N VGT + ++ A D D G N+++ + SN ++
Sbjct: 257 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD-ADIGENAKIHFSFSNLVSN 315
Query: 3029 LGK--FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
+ + F L+ TG I++ L + N + V A D G P ++A V + VT+ N +
Sbjct: 316 IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNV 373
Query: 3087 PEFSQSHM------SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
P ++ + + E+ + + + ++ D+DA NG + + +
Sbjct: 374 PSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF 433
Query: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYF 3200
S+ +L A LDYE +++ + + A D G + + V D NDN+PVF
Sbjct: 434 SNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT 493
Query: 3201 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFET 3260
++ EN G ++ ++ATDADSG NA I Y + F +D TG++T LD E
Sbjct: 494 VSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREK 553
Query: 3261 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 3320
+ Y T+ A + S TV + + N+ P F Y F + E P+ VG +
Sbjct: 554 EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLI 613
Query: 3321 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGS 3380
+D D G + V I F I+ +TG I + DREK+E + V A++ G
Sbjct: 614 TVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGR 671
Query: 3381 IRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPI---GTHVTFVSAFDSDSIPS 3436
+ + +VT+N V+D ND P+F + Y+ +P GT V V A D+D+ +
Sbjct: 672 VSRSSSAKVTIN--VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 729
Query: 3437 WSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASL 3496
+ Y I GN F+I+ +TG IT+ + D L ++ + V A D G P + S +
Sbjct: 730 -AEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 788
Query: 3497 L 3497
+
Sbjct: 789 V 789
Score = 219 bits (558), Expect = 5e-56
Identities = 181/643 (28%), Positives = 290/643 (45%), Gaps = 31/643 (4%)
Query: 2919 RINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSND 2978
RI TGEIF + + + + H F + + I D ND
Sbjct: 97 RIEEDTGEIFTTGA-RIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIND 155
Query: 2979 NAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEY-FISNDNHLGKFKLDND 3037
NAP F + + +N + +K A+D D G+N Y I + N G ++
Sbjct: 156 NAPLFPATVINISIPENSAINSKYTLPAAVDP-DVGINGVQNYELIKSQNIFGLDVIETP 214
Query: 3038 TG----WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSH 3093
G + V L + + + V +D G P SS A + ++VT+ N + P F ++
Sbjct: 215 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETE 274
Query: 3094 MSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS---SGNEEGIFAINSSTGILTLAK 3150
+ +IPE+ +G+ V + A D D N I +S S S +F +N++TG++T+ +
Sbjct: 275 IEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKE 334
Query: 3151 ALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL-- 3204
LD E H++ + A DGG + V VNV DVNDN P ++ + TV+
Sbjct: 335 PLDREETPNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 392
Query: 3205 ENAPSGTTVIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQS 3263
EN P T + + TD D+ N V +T L + N ++ +LD+E+ +
Sbjct: 393 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKE 452
Query: 3264 YHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFAS 3323
Y + + A + A + I++K N+ P F I E G + +V A+
Sbjct: 453 YAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSAT 512
Query: 3324 DRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRG 3383
D D G + E++YL+ G F ++++TG + V LDREKE++ +LAK+ G
Sbjct: 513 DADSGPNAEINYLL-GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGV--P 569
Query: 3384 ADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY 3442
VTV V+++D ND P+FT N Y + E +P V ++ D D +
Sbjct: 570 PLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDY---GDNSAV 626
Query: 3443 FIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLED 3502
+ +EN F+I+ QTG I DRE Y V A D G S + SA + + + D
Sbjct: 627 TLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVD 686
Query: 3503 INDNGPMLTV-----SEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
+NDN P+ V S V+ + PGT+V + + D D N
Sbjct: 687 VNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMN 729
Score = 186 bits (471), Expect = 7e-46
Identities = 165/558 (29%), Positives = 262/558 (46%), Gaps = 35/558 (6%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYS-ISSGNE 3133
+ + + N + P F + ++ +IPE+ +I S +A D D +NG+ Y I S N
Sbjct: 146 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 205
Query: 3134 EGIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ I + G L + K LD E + M + DGG+ R+ + V+V D ND
Sbjct: 206 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 265
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD----LFVIDP 3245
N PVF + ++ ENAP GT+V L+ATDAD G NA I ++ + S+ LF ++
Sbjct: 266 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 325
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
TG+IT + LD E ++ L V A + + VN+ N+ VP +
Sbjct: 326 TTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVN 383
Query: 3306 EI------SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
+ SE P T + + +D+D +G V + F++ ++
Sbjct: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF---TDHEIPFRLRPVFSNQFLLE 440
Query: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
+ LD E + ++K+LA + G + + + V D ND P+FT + +V I E
Sbjct: 441 NAAYLDYESTKEYAIKLLAADAG--KPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPE 498
Query: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
G + VSA D+DS P+ + +Y +G + FS++ +TG +TV +LDRE
Sbjct: 499 NNSPGIQLMKVSATDADSGPN-AEINYLLGP-DAPPEFSLDRRTGMLTVVKKLDREKEDK 556
Query: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
Y ++LA D+G P T + ++ V++ D NDN P+ T +E + V EN V + T
Sbjct: 557 YLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVT 616
Query: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSL-STAGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
DPD N LS F++ S GV+ DRE+ + V +D G
Sbjct: 617 DPDYGDNSA----VTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRV 672
Query: 3593 QMSSTGTVHITVIDQNDN 3610
SS+ V I V+D NDN
Sbjct: 673 SRSSSAKVTINVVDVNDN 690
Score = 110 bits (275), Expect = 3e-23
Identities = 132/499 (26%), Positives = 210/499 (42%), Gaps = 41/499 (8%)
Query: 3234 QSSDSDLFVIDPNTGVITTQGF-LDFET-------KQSYHLTVKAFNVPDEERCSFATVN 3285
++ D L I+ +TG I T G +D E + V+ +PDE F V
Sbjct: 89 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDE---IFRLVK 145
Query: 3286 IQ--LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
I+ ++ N+ P F + + I E + + A D D+G +G +Y + +
Sbjct: 146 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 205
Query: 3344 KGFQI-----NKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDA 3398
G + K Q+ V LDRE+++ +KV ++ G + + + V+VT D
Sbjct: 206 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT--DT 263
Query: 3399 NDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FS 3454
ND P+F V I E P+GT VT + A D+D I ++ + + N A F
Sbjct: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFH 322
Query: 3455 INPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--- 3511
+N TG IT+ LDRE P + L VLA D G A A +LV + D+NDN P +
Sbjct: 323 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR--AMVLVNVTDVNDNVPSIDIRY 380
Query: 3512 ----VSEGEVMENKRP-GTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVL 3566
V++ V+ P T + + TD D N G T + P S +L
Sbjct: 381 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHN-GRVTCFTDHEIPFRLRPVFSNQFLL 439
Query: 3567 STTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGN 3626
+D E ++ + ++ D+G P ++ + + I V D+NDN + V+ N
Sbjct: 440 ENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN 499
Query: 3627 LFPGGILGSVKPQDPDVLDSFHCSLTSGVT-----SLFSIPGGTCDLNSQPRSTDGTFDL 3681
PG L V D D + + G SL G + R + +
Sbjct: 500 NSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLF 559
Query: 3682 TVLSNDGVHSTVTSNIRVF 3700
T+L+ D +TSN+ VF
Sbjct: 560 TILAKDNGVPPLTSNVTVF 578
Score = 34.7 bits (78), Expect = 2.4
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 27/161 (16%)
Query: 4505 VPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPDNIPP 4564
V A+ G+ V+ + + +++ C Q KA +K +N + P+ P
Sbjct: 836 VAAVAGTITVVVVIFITAVVRCRQAPHLKAA------------QKNMQNSEWATPN---P 880
Query: 4565 YGDDMTV----RKQPEGNPKP---DIIERENPYLIYDETDIPHNSETIPSAPLASPEQEI 4617
M + +K+ + +PK +++ E D+ D N T+ P+ EQ +
Sbjct: 881 ENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKA--DDVDSDGNRVTL-DLPIDLEEQTM 937
Query: 4618 EHYD-IDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPL 4657
Y+ + ++ P D+ +HYK S P F IQ +PL
Sbjct: 938 GKYNWVTTPTTFKPDSPDLARHYKS-ASPQPAFQIQPETPL 977
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 325 bits (833), Expect = 7e-88
Identities = 250/811 (30%), Positives = 394/811 (48%), Gaps = 66/811 (8%)
Query: 24 LLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVG----------------TIQTR 67
LL ++ ++L H + + + EE P L+G T +
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 68 PGFTYRLSESHALFAINSSTGALYTTST-IDRESLPSDV---------INLVVLSSAPTY 117
Y+ + L I TG ++TT IDRE L + + + + +L
Sbjct: 63 FKLVYKTGDV-PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFR 121
Query: 118 PTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRII 177
++R L+ D+NDNAP+FP I ++ E+S+ + L A D D+G NGV ++Y +I
Sbjct: 122 LVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGV--QNYELI 179
Query: 178 RGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVN 237
+ F LD+ P G+ L+ + LDRE Y + V+VED G P+R +
Sbjct: 180 KSQNI--FGLDVIETPEGD-KMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQ 236
Query: 238 VTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQD-----E 292
V+V D NDN PVF + + +PE+A VG+SV Q+ A DAD G NA I + +
Sbjct: 237 VSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIA 296
Query: 293 GTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPV 352
F ++ TGLIT++EPLD E + L V A D G+ + RA L+ + DVNDN P
Sbjct: 297 RRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPS 354
Query: 353 VKFRYF-PATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQS 411
+ RY + + EN + T +AL+TVTD D+ NG ++ + + F ++
Sbjct: 355 IDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDAD-HNGRVTCFT---DHEIPFRLR- 409
Query: 412 SKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDH 471
N L++ A+ LD E Y + + +D G PP + A L I V D ND+
Sbjct: 410 PVFSNQFLLETAAYLDYESTKEYAIKLLAAD-AGKPP------LNQSAMLFIKVKDENDN 462
Query: 472 PPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGL 531
PVF+Q V++ E PG ++ +SA D DSG NA + Y ++ + F + +G+
Sbjct: 463 APVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LLGPDAPPEFSLDCRTGM 521
Query: 532 VTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVS 591
+T LDRE + + I A+D GV P S + V+++D ND PVF+ E Y+
Sbjct: 522 LTVVKK--LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNE-YNFY 578
Query: 592 VVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREE 651
V EN P + ++ TD D GDN V S+ + D F +D +G + S DRE+
Sbjct: 579 VPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD---FTIDSQTGVIRPNISFDREK 635
Query: 652 QAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFY----PVQYFAHIKENEPGGSY 707
Q Y+ V A D G +SS A++ ++++D+NDN PVF Y + P G+
Sbjct: 636 QESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTV 694
Query: 708 ITTVSATDPDLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVAT 766
+ V A D D G N V+YSI G+ R F ++ ++G I+ D + +++ + A
Sbjct: 695 VFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKAN 754
Query: 767 DGGNLQSP-NQAIVTITVLDTQDNPPVFSQV 796
D G S + IV + V ++ N + +++
Sbjct: 755 DLGQPDSLFSVVIVNLFVNESVTNATLINEL 785
Score = 298 bits (763), Expect = 9e-80
Identities = 231/737 (31%), Positives = 357/737 (48%), Gaps = 49/737 (6%)
Query: 804 ENVALGYHVGSVSASTMDLNS-----NISYLITTGDQKGMFAINQVTGQL-TTANVIDRE 857
ENV +G + ++ S + S + TGD + I + TG++ TT IDRE
Sbjct: 36 ENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVP-LIRIEEDTGEIFTTGARIDRE 94
Query: 858 ---------EQSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQA 908
E FY+++V + + ++D+NDN+P F + ++++ EN
Sbjct: 95 KLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAI 154
Query: 909 GHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAIN-------EKNGTISLLGPLD-VHAG 960
AVDPD G+NG+ Y L ++ +N+F ++ +K + + LD
Sbjct: 155 NSKYTLPAAVDPDVGINGVQNYELIKS-QNIFGLDVIETPEGDKMPQLIVQKELDREEKD 213
Query: 961 SYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQA 1020
+Y +++ D G PQ SS+ IL V V D NDN PVF + EV++ E+ PV + ++ A
Sbjct: 214 TYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHA 273
Query: 1021 SDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASDRA 1076
+D D G N +I ++ + + A +F G + IK LDRE + L+V+ASD
Sbjct: 274 TDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGG 333
Query: 1077 VEPLSATVNVTVILEDVNDNRP------LFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG 1130
+ P A V V V DVNDN P + N N T E + + ++ DKD
Sbjct: 334 LMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDAD 391
Query: 1131 PNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
NG V + P F L + +N + + + T ++ ++A D G P PL
Sbjct: 392 HNGRVTCFTDHEIP-FRLRPV---FSNQFLLETAAYLDYESTKEYAIKLLAADAGKP-PL 446
Query: 1191 KDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSII 1250
A + + +KD NDNAP F + F +I E+ + Q+ +VSA D D G N I+Y ++
Sbjct: 447 NQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LL 505
Query: 1251 KGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDEND 1310
+ +F++D +G +T++ KLD E Y I A D+G PL S T+ + I+D+ND
Sbjct: 506 GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQND 565
Query: 1311 NTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG 1370
N+P F + V EN+ V +T TD D GDN+ + SI N+ F+I TG
Sbjct: 566 NSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDEND--DFTIDSQTG 623
Query: 1371 SIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSF--PPGDI-FK 1427
I D E Q Y + A+D GR RSS+ V I+V D NDN P F PP + ++
Sbjct: 624 VIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYE 683
Query: 1428 SIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDRE 1487
++ + GT V V A D D +N ++ Y+I+ R + F ID+ G I + D
Sbjct: 684 LVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR-DLFAIDQETGNITLMEKCDVT 742
Query: 1488 FANLFELTVKANDQAVP 1504
L + VKAND P
Sbjct: 743 DLGLHRVLVKANDLGQP 759
Score = 293 bits (749), Expect = 4e-78
Identities = 212/679 (31%), Positives = 335/679 (49%), Gaps = 47/679 (6%)
Query: 954 PLDVHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNS 1013
P D H Y++E+ + +L V + + D+NDN+P+F +++ E+ +NS
Sbjct: 101 PRDEHC-FYEVEVAILPDEIFRL---VKIRFLIEDINDNAPLFPATVINISIPENSAINS 156
Query: 1014 RFFKVQASDKDSGANGEIAYTIAEGNTGDAFGI----FPDG----QLYIKSELDRELQDR 1065
++ A D D G NG Y + + + FG+ P+G QL ++ ELDRE +D
Sbjct: 157 KYTLPAAVDPDVGINGVQNYELIKSQ--NIFGLDVIETPEGDKMPQLIVQKELDREEKDT 214
Query: 1066 YVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAV 1125
YV+ V D S+T + V + D NDN P+F T E G+ V ++ A
Sbjct: 215 YVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHAT 274
Query: 1126 DKDFGPNGEVRYSFEMVQPD-----FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVI 1180
D D G N ++ +SF + + F L+A +G IT DRE T V+
Sbjct: 275 DADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE------TPNHKLLVL 328
Query: 1181 ATDQGIPQPLKDQATVHVYMKDINDNAP----KFLKDFYQATI--SESAANLTQVLRVSA 1234
A+D G+ + +A V V + D+NDN P +++ + T+ SE+ T++ ++
Sbjct: 329 ASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITV 385
Query: 1235 SDVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIP 1294
+D D +NG + R + S + LDYE+T Y++ + A D+G P
Sbjct: 386 TDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPP 445
Query: 1295 LNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSI 1354
LN + L I + DENDN P F +S + V + EN G ++ V+A D+DSG NA + Y +
Sbjct: 446 LNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-L 504
Query: 1355 TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFN 1414
G + FS+ TG + + KKLD E + Y I AKD G PP +S ++V + + D N
Sbjct: 505 LGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQN 564
Query: 1415 DNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEV 1474
DN P F + + EN+P +V +T DPD N ++ +I+ + + FTID
Sbjct: 565 DNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDE---NDDFTIDSQ 621
Query: 1475 KGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNA 1534
G I N DRE + VKA D R + VTI V D+NDN P+FI +
Sbjct: 622 TGVIRPNISFDREKQESYTFYVKAEDGG---RVSRSSSAKVTINVVDVNDNKPVFIVPPS 678
Query: 1535 LAAD----PSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASA 1589
+ PS G+V+ ++A D D G N E+ Y I+ G+T D F +D+ +G++ +
Sbjct: 679 NCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEK 738
Query: 1590 LVPSQL-IYNLIVSATDLG 1607
+ L ++ ++V A DLG
Sbjct: 739 CDVTDLGLHRVLVKANDLG 757
Score = 290 bits (742), Expect = 2e-77
Identities = 229/762 (30%), Positives = 363/762 (47%), Gaps = 44/762 (5%)
Query: 1670 VRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEIT 1729
+R EE T G +FT G + A + R++ C Y V+V AI F + ++
Sbjct: 75 IRIEEDT-GEIFTTGARIDREKLCAGIPRDEH-CFYEVEV-AILPDEIF---RLVKIRFL 128
Query: 1730 LQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRI 1789
++DINDN P+FP ++++++ EN SK A+D D G N + Y +I + + F +
Sbjct: 129 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK-SQNIFGL 187
Query: 1790 D----PESG---DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTP 1839
D PE LI + LDRE + Y + V+ +DG +SS + ++V+D ND+ P
Sbjct: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
Query: 1840 KFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNE---DDEDGIFFLNPITG 1896
F IPE+ G+ V + ATD D G N +I + + + +F LN TG
Sbjct: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
Query: 1897 VFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLN------SYS 1950
+ + LD E + L V A DGG V N+ DVNDN P + + +
Sbjct: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
Query: 1951 TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNG-VLKVLKALDRE 2009
L EN+P+ + + + VTD D N ++T V N +L+ LD E
Sbjct: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
Query: 2010 SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTV 2068
S Y + + D + P ++ +A + I + D NDN P F +T IPEN
Sbjct: 428 STKEYAIKLLAADAGKPPLNQ---SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 2069 VFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATD 2128
+ K A D DSGPN+ I Y L +FS+ G + + +LDRE+ Y T++A D
Sbjct: 485 LTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKD 544
Query: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
G P L+S+ V V ++D NDN+P+F Y + EN + + D D G N
Sbjct: 545 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSA 604
Query: 2189 VRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIV 2248
V I+ + N +F IDS TG I DREK +Y V+A D G R+ ++ V+I
Sbjct: 605 VTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
Query: 2249 LLDINDFVPVFELSP----YSVNVPE-NLGTLPRTILQVVARDDDRGSNSKLSYVLFGGN 2303
++D+ND PVF + P Y + +P N GT+ + QV+A D+D G N+++ Y + GGN
Sbjct: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTV---VFQVIAVDNDTGMNAEVRYSIVGGN 719
Query: 2304 EDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGSP-ALTGTGTINVIVDDVNDNV 2361
+ F + +G + + + D +++ A D G P +L +N+ V++ N
Sbjct: 720 TRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA 779
Query: 2362 PTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIG 2403
T ++ + T++ V++ +D K V + G
Sbjct: 780 -TLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAG 820
Score = 283 bits (723), Expect = 4e-75
Identities = 224/705 (31%), Positives = 342/705 (48%), Gaps = 51/705 (7%)
Query: 345 DVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQ 404
D+NDN P+ FPAT S+ EN+ + + L D D NG + +++
Sbjct: 131 DINDNAPL-----FPATVINISIPENSAINSKYTLPAAVDPDV-GINGVQNYELIKSQNI 184
Query: 405 RHFEV----QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVAS 460
+V + K+P L + K LDRE +Y + V V D G P RSS A
Sbjct: 185 FGLDVIETPEGDKMPQLIVQK---ELDREEKDTYVMKVKVEDG-GFPQ------RSSTAI 234
Query: 461 LVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYS---IVSG 517
L + V D ND+ PVF + V++ E AP G+ V+ + ATD D G NA + +S +VS
Sbjct: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
Query: 518 NGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVND 577
FH++ +GL+T LDRE L + A D G+ P + A ++V + DVND
Sbjct: 295 IARRLFHLNATTGLITIKEP--LDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVND 350
Query: 578 EKPVFS-----QPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRR-S 631
P P V + EN P T++ ++ TD D NG V TD
Sbjct: 351 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-----CFTDHEIP 405
Query: 632 FRLDPVSGR---LSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPV 688
FRL PV L T + LD E Y++ +LA D G PP + A + + + D NDN+PV
Sbjct: 406 FRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPV 465
Query: 689 FYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTR 748
F I EN G +T VSA D D G N + Y + F ++ ++G+++
Sbjct: 466 FTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVV 525
Query: 749 MALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVAL 808
LDRE++ Y I+A D G + V ++++D DN PVF+ Y+F V EN+
Sbjct: 526 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR 585
Query: 809 GYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVA 868
VG ++ + D N + ++ D+ F I+ TG + DRE+Q Y V A
Sbjct: 586 HGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKA 645
Query: 869 -SGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDE 922
GG V + V I V D+NDN P F+ + + V+ + G +FQ AVD D
Sbjct: 646 EDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDT 705
Query: 923 GVNGMVLYSL-KQNPKNLFAINEKNGTISLLGPLDV-HAGSYQIEILASDMGVP-QLSSS 979
G+N V YS+ N ++LFAI+++ G I+L+ DV G +++ + A+D+G P L S
Sbjct: 706 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 765
Query: 980 VILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKD 1024
VI+ ++V++ N+ + ++L + T + P N+ V + D
Sbjct: 766 VIVNLFVNESVTNATLINELVRKSTEAPVTP-NTEIADVSSPTSD 809
Score = 275 bits (702), Expect = 1e-72
Identities = 211/704 (29%), Positives = 315/704 (44%), Gaps = 41/704 (5%)
Query: 613 GDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSM 672
GD +R E R+D R + + R+E FY + V P
Sbjct: 70 GDVPLIRIEEDTGEIFTTGARID----REKLCAGIPRDEHCFYEVEVAIL-----PDEIF 120
Query: 673 ARINVSLL--DINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISA 730
+ + L DINDN+P+F I EN S T +A DPD+G NG Y +
Sbjct: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
Query: 731 G------DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVL 784
D + + + LDREEK Y +++ DGG Q + AI+ ++V
Sbjct: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
Query: 785 DTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMF 839
DT DN PVF + + EN +G V + A+ D+ N + + + +F
Sbjct: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
Query: 840 AINQVTGQLTTANVIDREEQSFYQLKVVAS-GGTVTGDTMVNITVKDLNDNSP-----HF 893
+N TG +T +DREE ++L V+AS GG + MV + V D+NDN P +
Sbjct: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
Query: 894 LQAI-ESVNVVENWQAGHSIFQAKAVDPDEGVNGMVL-YSLKQNPKNLFAINEKNGTISL 951
+ + ++V + EN I D D NG V ++ + P L + +
Sbjct: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
Query: 952 LGPLDVHAGS-YQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEP 1010
LD + Y I++LA+D G P L+ S +L + V D NDN+PVF Q V++ E+
Sbjct: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 1011 VNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLYIKSELDRELQDRYVLMV 1070
+ KV A D DSG N +I Y + + G L + +LDRE +D+Y+ +
Sbjct: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 1071 VASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFG 1130
+A D V PL++ V V V + D NDN P+F Y FY E VG ++ D D+G
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 1131 PNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPL 1190
N V S DF + + +G I FDRE ++F V A D G
Sbjct: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREK------QESYTFYVKAEDGG-RVSR 653
Query: 1191 KDQATVHVYMKDINDNAPKFL---KDFYQATISESAANLTQVLRVSASDVDEGNNGLIHY 1247
A V + + D+NDN P F+ + + S T V +V A D D G N + Y
Sbjct: 654 SSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRY 713
Query: 1248 SIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSG 1291
SI+ GN FAID +G +TL+ K D + ++++A D G
Sbjct: 714 SIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLG 757
Score = 263 bits (673), Expect = 2e-69
Identities = 197/656 (30%), Positives = 318/656 (48%), Gaps = 39/656 (5%)
Query: 779 VTITVLDTQDNPPVFSQVAYSFVVFENVALG--YHVGSVSASTMDLNSNISY-LITTGDQ 835
+ + D DN P+F + + EN A+ Y + + + +N +Y LI + +
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 184
Query: 836 KGMFAINQVTG----QLTTANVIDREEQSFYQLKVVASGGTV---TGDTMVNITVKDLND 888
G+ I G QL +DREE+ Y +KV G + ++ ++V D ND
Sbjct: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 244
Query: 889 NSPHFLQAIESVNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKN----LFAINE 944
N P F + V++ EN G S+ Q A D D G N + +S N LF +N
Sbjct: 245 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 304
Query: 945 KNGTISLLGPLD-VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFD------ 997
G I++ PLD ++++ +LASD G+ + + ++ V V DVNDN P D
Sbjct: 305 TTGLITIKEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVN 362
Query: 998 QLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQLY-IKS 1056
++ V LSE+ P+N++ + +DKD+ NG + +F + L +
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 1057 ELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAG 1116
LD E Y + ++A+D PL+ + + + ++D NDN P+F + T E G
Sbjct: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
Query: 1117 SFVGKVSAVDKDFGPNGEVRYSFEM-VQPDFELHAISGEITNTHQFDRESLMRRRGTAVF 1175
+ KVSA+D D GPN ++ Y P+F L +G +T + DRE + +
Sbjct: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDK------Y 536
Query: 1176 SFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSAS 1235
FT++A D G+P PL TV V + D NDN+P F + Y + E+ V ++ +
Sbjct: 537 LFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVT 595
Query: 1236 DVDEGNNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPL 1295
D D G+N + SI+ N++ F IDS +G + D E +Y+ ++A D G +
Sbjct: 596 DPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR 653
Query: 1296 NSTCTLNIDILDENDNTPSF---PKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYY 1352
+S+ + I+++D NDN P F P + + VL + G +V V A D+D+G NA++ Y
Sbjct: 654 SSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRY 713
Query: 1353 SITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVI 1408
SI G N F+I TG+I L +K D L+++ + A D G+P S SVVI
Sbjct: 714 SIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP--DSLFSVVI 767
Score = 249 bits (636), Expect = 5e-65
Identities = 218/719 (30%), Positives = 322/719 (44%), Gaps = 67/719 (9%)
Query: 2203 RIDSVTGAI-TVAKPLDREKT----PTYHLTVQATDRGSTPRTDTSTVSIVLL--DINDF 2255
RI+ TG I T +DREK P + P V I L DIND
Sbjct: 76 RIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDN 135
Query: 2256 VPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA--- 2312
P+F + ++++PEN + L A D D G N +Y L N F L
Sbjct: 136 APLFPATVINISIPENSAINSKYTLPA-AVDPDVGINGVQNYELI--KSQNIFGLDVIET 192
Query: 2313 -----SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASK 2367
+L V + LDRE K+ +V+ + D G P + T + V V D NDN P F
Sbjct: 193 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 252
Query: 2368 AYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGN-------SQFTINPSTGQIITS 2420
+IPE+AP GT V ++A+DAD +NA I N F +N +TG I
Sbjct: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
Query: 2421 ALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYV-----THI 2475
LDRE N+ L+V+ SD G + + VLV VTDVNDN P V T +
Sbjct: 313 EPLDREETPNHKLLVLASDGGL---MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVV 369
Query: 2476 PSPTLP-GSFVFAVTVTDADIGPNS--------ELHYSLSGRNSEKFHIDPLRGAIMAAG 2526
S +P + + +TVTD D N E+ + L S +F ++ A
Sbjct: 370 LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE-----TAAYL 424
Query: 2527 PLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQTFMFPENQPVSSL 2585
E + D G P S + ++ ++ D P T PEN
Sbjct: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 2586 VTTITGSSLRGEPMS--YYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARD 2643
+T ++ P + Y+ + F +D TG +++ + LD EK KY+ I A+D
Sbjct: 485 LTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKD 544
Query: 2644 GGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR--KILTVSAMDKDSGPNG 2701
G PP +S + ++++D NDN+P+F + + + ENL PR + ++ D D G N
Sbjct: 545 NGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENL-PRHGTVGLITVTDPDYGDNS 603
Query: 2702 QLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMI 2761
+ I++ N + F+I+ TG IR DREK Y +K+ D G S+S+S KV I
Sbjct: 604 AVTLSILDEN--DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
Query: 2762 NILDENDNAPRF-----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASL 2816
N++D NDN P F + + +P +P G V +V D D G+NA RYSI+ +
Sbjct: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
Query: 2817 P--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVS----TDVTIFVTDINDNA 2869
F I+ TG+I + + D +R+ V A+D G S V +FV + NA
Sbjct: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNA 779
Score = 240 bits (613), Expect = 2e-62
Identities = 228/805 (28%), Positives = 365/805 (45%), Gaps = 72/805 (8%)
Query: 1425 IFKSIVENIPIGTSVISVTAH-DPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTN-A 1482
I + + EN+ IG + + P+ + + + ++ + I+E G I+T A
Sbjct: 30 IREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGA 89
Query: 1483 EIDREFAN---------LFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQN 1533
IDRE +E+ V + + L + L+ D+NDN P+F +
Sbjct: 90 RIDREKLCAGIPRDEHCFYEVEVAILPDEI------FRLVKIRFLIEDINDNAPLFPATV 143
Query: 1534 ALAADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASAL 1590
+ P ++ I S T A DPD G NG YE+I +++ GD ++ +
Sbjct: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGD-KMPQLI 202
Query: 1591 VPSQL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGE 1642
V +L Y + V D G +R ST L + + + PVF + + + E
Sbjct: 203 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENA 262
Query: 1643 PIGTNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQG 1701
P+GT+V + A + G A + + ++ RLF + TG+I LDRE+
Sbjct: 263 PVGTSVTQLHATDADIGENAKIHFSFSNL--VSNIARRLFHLNATTGLITIKEPLDREET 320
Query: 1702 ACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGD 1755
L+ + S RA V + + D+NDN P + + + ENI
Sbjct: 321 PNHKLL----VLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPL 376
Query: 1756 GSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGD---LIATRRLDRERRSKYSL 1812
+KI +T D D N V T + + FR+ P + L LD E +Y++
Sbjct: 377 NTKIALITVTDKDADHNGRV--TCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAI 434
Query: 1813 -LVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDD 1868
L+ AD G L S M + I V D ND+ P F++ + IPE+ PG + + A D
Sbjct: 435 KLLAADAGKPPLNQSAM-LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDA 493
Query: 1869 DSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTT- 1927
DSG N +I Y++ D F L+ TG+ + + LD E + Y+ T+ A+D G T
Sbjct: 494 DSGPNAKINYLLGPDAPPE-FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTS 552
Query: 1928 -IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASG 1986
+ V+ +I+D NDN P+F+ N Y+ + ENLP TV + VTD D G NS +T SI
Sbjct: 553 NVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSIL-- 610
Query: 1987 DSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVN 2045
D FT+D + GV++ + DRE Q Y V+ D ++ S S+A+V+I ++DVN
Sbjct: 611 DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRS---SSAKVTINVVDVN 667
Query: 2046 DNPPTFLSPKLT-----YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIG 2100
DN P F+ P +P P TVVF+ A D D+G N+ + Y+++ GN +
Sbjct: 668 DNKPVFIVPPSNCSYELVLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLF 724
Query: 2101 TID---GEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQA 2157
ID G + L + D ++ + + V A D GQP S +V + ++ + N
Sbjct: 725 AIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINE 784
Query: 2158 LYKVEINENTLTGTDIIQVFAADGD 2182
L + T+I V + D
Sbjct: 785 LVRKSTEAPVTPNTEIADVSSPTSD 809
Score = 235 bits (600), Expect = 7e-61
Identities = 214/745 (28%), Positives = 343/745 (46%), Gaps = 68/745 (9%)
Query: 2384 LLVNASDADASKNAVIRIIGGNSQFTINPSTGQIITS-ALLDRET------KDNYTLVVV 2436
L+ N S A + ++ G I TG+I T+ A +DRE +D + V
Sbjct: 51 LIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEV 110
Query: 2437 CSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIG 2496
A P+ + + + D+NDN P F IP + S D D+G
Sbjct: 111 -EVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 169
Query: 2497 PNSELHYSLSGRNSEKFHIDPLRGA-------IMAAGPLNGASEVTFSVHVK-DGGSFPK 2548
N +Y L ++ F +D + ++ L+ + T+ + VK + G FP+
Sbjct: 170 INGVQNYELI-KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQ 228
Query: 2549 TDSTTVTVRFVNKAD--FPKVRAKEQTFMFPENQPVSSLVTTITGSSLR-GEPMSYYIAS 2605
ST + V + P + E PEN PV + VT + + GE + +
Sbjct: 229 RSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSF 288
Query: 2606 GNLGNT-----FQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVL 2660
NL + F ++ TG ++I +PLD E+ + + + A DGG P + +++T
Sbjct: 289 SNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT-- 346
Query: 2661 DVNDNAPIFKEDPFISEI------LENLSPR-KILTVSAMDKDSGPNGQL----DYEI-- 2707
DVNDN P ++ + EN+ KI ++ DKD+ NG++ D+EI
Sbjct: 347 DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPF 406
Query: 2708 -VNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDE 2766
+ N F + A LD E Y + + ++D G P + S + I + DE
Sbjct: 407 RLRPVFSNQFLLETAAY-------LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
Query: 2767 NDNAPRFSQIF-SAHVPENSPLGYTVTRVTTSDEDIGINAISRYSI-MDASLPFTINPST 2824
NDNAP F+Q F + +PEN+ G +T+V+ D D G NA Y + DA F+++ T
Sbjct: 460 NDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRT 519
Query: 2825 GDIVISRPLNREDTDRYRIRVSAHDSGWT-VSTDVTIFVT--DINDNAPRFSRTSYYLDC 2881
G + + + L+RE D+Y + A D+G ++++VT+FV+ D NDN+P F+ Y
Sbjct: 520 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYV 579
Query: 2882 PELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGF 2941
PE V + TDPD G N V I +++ F I++ TG I N++ F
Sbjct: 580 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVI-------RPNIS-F 631
Query: 2942 SNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFL---KSKYFTPVTKNVKV 2998
++F V + D G+ S S VTIN+VD NDN P F+ + + V +
Sbjct: 632 DREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNP 691
Query: 2999 GTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSL-ISDLNQNFFI 3057
GT + +V A+D+ D G+N+EV Y I N F +D +TG I++ ++DL + +
Sbjct: 692 GTVVFQVIAVDN-DTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLH-RV 749
Query: 3058 TVTAKDKGNP-PLSSQATVHITVTE 3081
V A D G P L S V++ V E
Sbjct: 750 LVKANDLGQPDSLFSVVIVNLFVNE 774
Score = 214 bits (546), Expect = 1e-54
Identities = 202/734 (27%), Positives = 327/734 (44%), Gaps = 60/734 (8%)
Query: 2858 VTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNG-QVFYFIKSQSE 2916
+ + DINDNAP F T + PE + I SK T A DPD G NG Q + IKSQ+
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 184
Query: 2917 YFRINATTGE-------IFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTV 2969
+ T E I K++ + + T V + D G P S +
Sbjct: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVE---------DGGFPQRSSTAIL 235
Query: 2970 TINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISN-DNH 3028
+++ D+NDN P F +++ + +N VGT + ++ A D D G N+++ + SN ++
Sbjct: 236 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD-ADIGENAKIHFSFSNLVSN 294
Query: 3029 LGK--FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHT 3086
+ + F L+ TG I++ L + N + V A D G P ++A V + VT+ N +
Sbjct: 295 IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDNV 352
Query: 3087 PEFSQSHM------SATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
P ++ + + E+ + + + ++ D+DA NG + + +
Sbjct: 353 PSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF 412
Query: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYF 3200
S+ +L A LDYE +++ + + A D G + + V D NDN+PVF
Sbjct: 413 SNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT 472
Query: 3201 PTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFET 3260
++ EN G + ++A DADSG NA I Y + F +D TG++T LD E
Sbjct: 473 VSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREK 532
Query: 3261 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 3320
+ Y T+ A + S TV + + N+ P F Y F + E P+ VG +
Sbjct: 533 EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLI 592
Query: 3321 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGS 3380
+D D G + V I F I+ +TG I + DREK+E + V A++ G
Sbjct: 593 TVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGR 650
Query: 3381 IRGADIDEVTVNVTVLDAND-PPIFTL---NIYSVQISEGVPIGTHVTFVSAFDSDSIPS 3436
+ + +VT+N V+D ND P+F + N + GT V V A D+D+ +
Sbjct: 651 VSRSSSAKVTIN--VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMN 708
Query: 3437 WSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASL 3496
+ Y I GN F+I+ +TG IT+ + D L ++ + V A D G P + S +
Sbjct: 709 -AEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV-V 766
Query: 3497 LVTLEDINDNGPMLTVSEGEVMENKRPGTLVMTL--QSTDPDLPPNQGPFTYYLLSTGPA 3554
+V L V E+ TL+ L +ST+ + PN T + P
Sbjct: 767 IVNL---------------FVNESVTNATLINELVRKSTEAPVTPN----TEIADVSSPT 807
Query: 3555 TSYFSLSTAGVLST 3568
+ Y + A V T
Sbjct: 808 SDYVKILVAAVAGT 821
Score = 189 bits (481), Expect = 5e-47
Identities = 165/555 (29%), Positives = 260/555 (46%), Gaps = 29/555 (5%)
Query: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYS-ISSGNE 3133
+ + + N + P F + ++ +IPE+ +I S +A D D +NG+ Y I S N
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 184
Query: 3134 EGIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
G+ I + G L + K LD E + M + DGG+ R+ + V+V D ND
Sbjct: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 244
Query: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD----LFVIDP 3245
N PVF + ++ ENAP GT+V L+ATDAD G NA I ++ + S+ LF ++
Sbjct: 245 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 304
Query: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYF 3305
TG+IT + LD E ++ L V A + + VN+ N+ VP +
Sbjct: 305 TTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVN 362
Query: 3306 EI------SEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSG 3359
+ SE P T + + +D+D +G V + + + +
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 3360 ILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVP 3418
LD E + ++K+LA + G + + + V D ND P+FT + +V I E
Sbjct: 423 YLDYESTKEYAIKLLAADAG--KPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 3419 IGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNL 3478
G +T VSA D+DS P+ ++ +Y +G + FS++ +TG +TV +LDRE Y
Sbjct: 481 PGIQLTKVSAMDADSGPN-AKINYLLGP-DAPPEFSLDCRTGMLTVVKKLDREKEDKYLF 538
Query: 3479 SVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQSTDPD 3536
++LA D+G P T + ++ V++ D NDN P+ T +E V EN V + TDPD
Sbjct: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPD 598
Query: 3537 LPPNQGPFTYYLLSTGPATSYFSL-STAGVLSTTREIDREQIADFYLSVVTKDSGVPQMS 3595
N LS F++ S GV+ DRE+ + V +D G S
Sbjct: 599 YGDNSA----VTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRS 654
Query: 3596 STGTVHITVIDQNDN 3610
S+ V I V+D NDN
Sbjct: 655 SSAKVTINVVDVNDN 669
Score = 173 bits (438), Expect = 4e-42
Identities = 148/488 (30%), Positives = 233/488 (47%), Gaps = 31/488 (6%)
Query: 3186 DVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVI 3243
D+NDN+P+F + ++ EN+ + A D D G N V Y + S + L VI
Sbjct: 131 DINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVI 190
Query: 3244 DPNTG----VITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFV 3299
+ G + Q LD E K +Y + VK + +R S A + + + TN+ P F
Sbjct: 191 ETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFK 250
Query: 3300 SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYL---IFGNSRKKGFQINKKTGQIY 3356
I E AP GT V ++ A+D D+G + ++H+ + N ++ F +N TG I
Sbjct: 251 ETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLIT 310
Query: 3357 VSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYS-----V 3411
+ LDRE+ L VLA + G + + V VNVT ++ N P I I + V
Sbjct: 311 IKEPLDREETPNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTV 368
Query: 3412 QISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQ---ITVTAEL 3468
+SE +P+ T + ++ D D+ + R + F + F + P + A L
Sbjct: 369 VLSENIPLNTKIALITVTDKDADHN-GRVTCFT---DHEIPFRLRPVFSNQFLLETAAYL 424
Query: 3469 DRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVS--EGEVMENKRPGTL 3526
D E+ Y + +LA D+G P SA L + ++D NDN P+ T S + EN PG
Sbjct: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
Query: 3527 VMTLQSTDPDLPPNQGPFTYYLLSTGP-ATSYFSLST-AGVLSTTREIDREQIADFYLSV 3584
+ + + D D PN YLL GP A FSL G+L+ +++DRE+ + ++
Sbjct: 485 LTKVSAMDADSGPNAK--INYLL--GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 3585 VTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVL 3644
+ KD+GVP ++S TV +++IDQNDN E NL G +G + DPD
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 3645 DSFHCSLT 3652
D+ +L+
Sbjct: 601 DNSAVTLS 608
Score = 135 bits (340), Expect = 1e-30
Identities = 121/420 (28%), Positives = 192/420 (45%), Gaps = 34/420 (8%)
Query: 90 LYTTSTIDRESLPSDVINLVVLSSAPTYPTEVRVL---VRDLNDNAPVFPDPSIVVTFKE 146
L T + +D ES I L+ + + +L V+D NDNAPVF + V+ E
Sbjct: 418 LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPE 477
Query: 147 DSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGNEAG-RFRLDITLNPSGEGAFLHLVSK 205
++S G Q+ +A D+D G N + G +A F LD L +V K
Sbjct: 478 NNSPGIQLTKVSAMDADSGPNA----KINYLLGPDAPPEFSLDCRTG------MLTVVKK 527
Query: 206 GGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVV 265
LDRE +Y + +D G P + V V++ D NDN PVF + Y VPE+
Sbjct: 528 --LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPR 585
Query: 266 GSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQA 325
+V + D D G N+ + + DE F +D +TG+I D E + Y+ V+A
Sbjct: 586 HGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKA 645
Query: 326 MDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDA 385
D G S + A+ I ++DVNDN PV F P+ Y V + GTVV + D
Sbjct: 646 EDGGRVSRSSSAKVTINVVDVNDNKPV--FIVPPSNCSYELVLPSTNPGTVVFQVIAVDN 703
Query: 386 DSPAANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYG 445
D+ N + I+GGN + F + + N++L++ D + + + V +D G
Sbjct: 704 DT-GMNAEVRYSIVGGNTRDLFAI-DQETGNITLMEKCDVTD---LGLHRVLVKAND-LG 757
Query: 446 APPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAP--PGSYVSGISATDGD 503
P + SV + +FVN+ + + ++ V + S EAP P + ++ +S+ D
Sbjct: 758 QP-----DSLFSVVIVNLFVNESVTNATLINELVRK---STEAPVTPNTEIADVSSPTSD 809
Score = 112 bits (281), Expect = 7e-24
Identities = 133/499 (26%), Positives = 211/499 (42%), Gaps = 41/499 (8%)
Query: 3234 QSSDSDLFVIDPNTGVITTQGF-LDFET-------KQSYHLTVKAFNVPDEERCSFATVN 3285
++ D L I+ +TG I T G +D E + V+ +PDE F V
Sbjct: 68 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDE---IFRLVK 124
Query: 3286 IQ--LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRK 3343
I+ ++ N+ P F + + I E + + A D D+G +G +Y + +
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNI 184
Query: 3344 KGFQI-----NKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDA 3398
G + K Q+ V LDRE+++ +KV ++ G + + + V+VT D
Sbjct: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT--DT 242
Query: 3399 NDP-PIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FS 3454
ND P+F V I E P+GT VT + A D+D I ++ + + N A F
Sbjct: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDAD-IGENAKIHFSFSNLVSNIARRLFH 301
Query: 3455 INPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT--- 3511
+N TG IT+ LDRE P + L VLA D G A A +LV + D+NDN P +
Sbjct: 302 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR--AMVLVNVTDVNDNVPSIDIRY 359
Query: 3512 ----VSEGEVMENKRP-GTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVL 3566
V++ V+ P T + + TD D N G T + P S +L
Sbjct: 360 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHN-GRVTCFTDHEIPFRLRPVFSNQFLL 418
Query: 3567 STTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGN 3626
T +D E ++ + ++ D+G P ++ + + I V D+NDN + V+ N
Sbjct: 419 ETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPEN 478
Query: 3627 LFPGGILGSVKPQDPDVLDSFHCSLTSGVT-----SLFSIPGGTCDLNSQPRSTDGTFDL 3681
PG L V D D + + G SL G + R + +
Sbjct: 479 NSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLF 538
Query: 3682 TVLSNDGVHSTVTSNIRVF 3700
T+L+ D +TSN+ VF
Sbjct: 539 TILAKDNGVPPLTSNVTVF 557
Score = 36.2 bits (82), Expect = 0.84
Identities = 39/159 (24%), Positives = 67/159 (42%), Gaps = 23/159 (14%)
Query: 4505 VPAIVGSCATVLALLVLSLILCNQCRGKKAKNPKEEKKPKEKKKKGSENVAFDDPDNIPP 4564
V A+ G+ V+ + + +++ C Q KA +K K+ SE A +P+N
Sbjct: 815 VAAVAGTITVVVVIFITAVVRCRQAPHLKAA---------QKNKQNSE-WATPNPEN--- 861
Query: 4565 YGDDMTVRKQPEGNPKPDIIERENPYLIYDET-----DIPHNSETIPSAPLASPEQEIEH 4619
M + K+ + K ++ +ET D N T+ P+ EQ +
Sbjct: 862 --RQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTL-DLPIDLEEQTMGK 918
Query: 4620 YD-IDNASSIAPSDADIIQHYKQFRSHTPKFSIQRHSPL 4657
Y+ + ++ P D+ +HYK S P F IQ +PL
Sbjct: 919 YNWVTTPTTFKPDSPDLARHYKS-ASPQPAFQIQPETPL 956
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 191,584,920
Number of Sequences: 37866
Number of extensions: 9307246
Number of successful extensions: 79560
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 343
Number of HSP's successfully gapped in prelim test: 254
Number of HSP's that attempted gapping in prelim test: 22321
Number of HSP's gapped (non-prelim): 8375
length of query: 4981
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4857
effective length of database: 13,552,134
effective search space: 65822714838
effective search space used: 65822714838
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.