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Search of human proteins with 157819143
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157819143 IgLON family member 5 [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157819143 IgLON family member 5 [Homo sapiens] 679 0.0
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 313 2e-85
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 312 2e-85
gi|45594240 limbic system-associated membrane protein [Homo sapi... 298 5e-81
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 295 5e-80
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 294 7e-80
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 289 3e-78
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 287 8e-78
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 259 2e-69
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 97 2e-20
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 97 2e-20
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 92 5e-19
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 92 5e-19
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 92 5e-19
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 92 5e-19
gi|110349719 titin isoform N2-A [Homo sapiens] 91 1e-18
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 91 2e-18
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 91 2e-18
gi|4827022 contactin 2 precursor [Homo sapiens] 86 5e-17
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 86 6e-17
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 85 8e-17
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 84 2e-16
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 83 4e-16
gi|118572606 hemicentin 1 [Homo sapiens] 82 9e-16
gi|4758822 nephrin precursor [Homo sapiens] 81 1e-15
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 81 1e-15
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 81 1e-15
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 77 2e-14
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 77 2e-14
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens] 77 2e-14
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 679 bits (1752), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHV 60
MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHV
Sbjct: 1 MPPPAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHV 60
Query: 61 TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP 120
TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP
Sbjct: 61 TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP 120
Query: 121 YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL 180
YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL
Sbjct: 121 YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL 180
Query: 181 EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA 240
EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA
Sbjct: 181 EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA 240
Query: 241 MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS 300
MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS
Sbjct: 241 MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS 300
Query: 301 SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM 336
SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM
Sbjct: 301 SASMRLLRPGSLENSAPRPPGLLALLSALGWLWWRM 336
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 313 bits (801), Expect = 2e-85
Identities = 167/328 (50%), Positives = 225/328 (68%), Gaps = 11/328 (3%)
Query: 11 RLLAAAALAGLAVISRGLLSQSLEFNSPA--DNYTVCEGDNATLSCFIDEHVTRVAWLNR 68
+ L +L L ++ G+ +S + P DN TV +G++ATL C ID+ VTRVAWLNR
Sbjct: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNR 71
Query: 69 SNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI 128
S ILYAGND+W+ DPRV +L+NTP ++SI+I V + DEG YTCS QT + P T++V+LI
Sbjct: 72 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
Query: 129 VHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLR----DGFTSEGEILEISD 184
V VP +I+NISS +TVNEG +V LLCLA+GRPEPTVTWR L GF SE E LEISD
Sbjct: 132 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 191
Query: 185 IQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVP 244
I+R Q+GEYEC N V +APD R+V +TVNYPP I+ + ++G+ +L CEA AVP
Sbjct: 192 IKRDQSGEYECSALNDV-AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVP 250
Query: 245 PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
A+FQW+K++ L++G +G++++ + S L F NVS + YGNYTC A N+LG ++AS+
Sbjct: 251 MAEFQWFKEETRLATGL-DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
Query: 305 RLLRPGSL---ENSAPRPPGLLALLSAL 329
L PG++ NSA R L L L
Sbjct: 310 TLYGPGAVIDGVNSASRALACLWLSGTL 337
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 312 bits (800), Expect = 2e-85
Identities = 162/302 (53%), Positives = 213/302 (70%), Gaps = 9/302 (2%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEE 94
F DN TV +G++ATL C ID+ VTRVAWLNRS ILYAGND+W+ DPRV +L+NTP +
Sbjct: 31 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 90
Query: 95 FSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLC 154
+SI+I V + DEG YTCS QT + P T++V+LIV VP +I+NISS +TVNEG +V LLC
Sbjct: 91 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 150
Query: 155 LAVGRPEPTVTWRQLR----DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
LA+GRPEPTVTWR L GF SE E LEISDI+R Q+GEYEC N V +APD R+V
Sbjct: 151 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-AAPDVRKV 209
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
+TVNYPP I+ + ++G+ +L CEA AVP A+FQW+K++ L++G +G++++ +
Sbjct: 210 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL-DGMRIENK 268
Query: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSL---ENSAPRPPGLLALLS 327
S L F NVS + YGNYTC A N+LG ++AS+ L PG++ NSA R L L
Sbjct: 269 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRALACLWLSG 328
Query: 328 AL 329
L
Sbjct: 329 TL 330
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 298 bits (763), Expect = 5e-81
Identities = 154/295 (52%), Positives = 203/295 (68%), Gaps = 6/295 (2%)
Query: 21 LAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWT 80
L ++ GL +S++FN DN TV +GD A L C +++ ++VAWLNRS I++AG+D+W+
Sbjct: 20 LCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWS 79
Query: 81 SDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS 140
DPRV L E+S+ I +V + DEG YTCS QT+H+P T+QVYLIV VP +I NISS
Sbjct: 80 LDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISS 139
Query: 141 PVTVNEGGNVNLLCLAVGRPEPTVTWRQLRD---GFTSEGEILEISDIQRGQAGEYECVT 197
VTVNEG NV L+C+A GRPEP +TWR L F E E LEI I R Q+G+YEC
Sbjct: 140 DVTVNEGSNVTLVCMANGRPEPVITWRHLTPTGREFEGEEEYLEILGITREQSGKYECKA 199
Query: 198 HNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
N V+SA D ++V VTVNYPPTIT+ S GR A L+CEA AVP DF+WY+DD +
Sbjct: 200 ANEVSSA-DVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRI 258
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSL 312
+S A GL++++ +S L NV+ HYGNYTC AAN+LG ++AS+ L RPGS+
Sbjct: 259 NS--ANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSV 311
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 295 bits (754), Expect = 5e-80
Identities = 163/327 (49%), Positives = 211/327 (64%), Gaps = 10/327 (3%)
Query: 11 RLLAAAALAGLAVISRGLLSQSLEFNSPA--DNYTVCEGDNATLSCFIDEHVTRVAWLNR 68
+ L +L L ++ G+ +S + P DN TV +G++ATL C ID VTRVAWLNR
Sbjct: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNR 71
Query: 69 SNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI 128
S ILYAGND+W DPRV LL NT ++SI I V + DEG YTCS QT + P T++V+LI
Sbjct: 72 STILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
Query: 129 VHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRD---GFTSEGEILEISDI 185
V V +IV ISS +++NEG N++L C+A GRPEPTVTWR + GF SE E LEI I
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPP 245
R Q+G+YEC N V +AP RRV VTVNYPP I++ +G+ L+CEA AVP
Sbjct: 192 TREQSGDYECSASNDV-AAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPS 250
Query: 246 ADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMR 305
A+FQWYKDD+ L G +G+KV+ S L+F NVS YGNYTC A+N+LG ++AS+
Sbjct: 251 AEFQWYKDDKRLIEG-KKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIM 309
Query: 306 LLRPGS---LENSAPRPPGLLALLSAL 329
L PG+ + N R G + LL L
Sbjct: 310 LFGPGAVSEVSNGTSRRAGCVWLLPLL 336
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 294 bits (753), Expect = 7e-80
Identities = 158/301 (52%), Positives = 199/301 (66%), Gaps = 8/301 (2%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEE 94
F DN TV +G++ATL C ID VTRVAWLNRS ILYAGND+W DPRV LL NT +
Sbjct: 38 FPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQ 97
Query: 95 FSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLC 154
+SI I V + DEG YTCS QT + P T++V+LIV V +IV ISS +++NEG N++L C
Sbjct: 98 YSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTC 157
Query: 155 LAVGRPEPTVTWRQLRD---GFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL 211
+A GRPEPTVTWR + GF SE E LEI I R Q+G+YEC N V +AP RRV
Sbjct: 158 IATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDV-AAPVVRRVK 216
Query: 212 VTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER 271
VTVNYPP I++ +G+ L+CEA AVP A+FQWYKDD+ L G +G+KV+
Sbjct: 217 VTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEG-KKGVKVENRP 275
Query: 272 TRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGS---LENSAPRPPGLLALLSA 328
S L+F NVS YGNYTC A+N+LG ++AS+ L PG+ + N R G + LL
Sbjct: 276 FLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPL 335
Query: 329 L 329
L
Sbjct: 336 L 336
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 289 bits (739), Expect = 3e-78
Identities = 158/322 (49%), Positives = 209/322 (64%), Gaps = 7/322 (2%)
Query: 11 RLLAAAALAGLAVISRGLLSQSLEFNSPA--DNYTVCEGDNATLSCFIDEHVTRVAWLNR 68
+ L +L L ++ G+ +S + P DN TV +G++ATL C ID VTRVAWLNR
Sbjct: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNR 71
Query: 69 SNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI 128
S ILYAGND+W DPRV LL NT ++SI I V + DEG YTCS QT + P T++V+LI
Sbjct: 72 STILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
Query: 129 VHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRD---GFTSEGEILEISDI 185
V V +IV ISS +++NEG N++L C+A GRPEPTVTWR + GF SE E LEI I
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPP 245
R Q+G+YEC N V +AP RRV VTVNYPP I++ +G+ L+CEA AVP
Sbjct: 192 TREQSGDYECSASNDV-AAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPS 250
Query: 246 ADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMR 305
A+FQWYKDD+ L G +G+KV+ S L+F NVS YGNYTC A+N+LG ++AS+
Sbjct: 251 AEFQWYKDDKRLIEG-KKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIM 309
Query: 306 LLRPGSLENSAPRPPGLLALLS 327
L + + + PG ++ +S
Sbjct: 310 LFEVKTTALTPWKGPGAVSEVS 331
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 287 bits (735), Expect = 8e-78
Identities = 155/301 (51%), Positives = 200/301 (66%), Gaps = 7/301 (2%)
Query: 11 RLLAAAALAGLAVISRGLLSQSLEFNSPA--DNYTVCEGDNATLSCFIDEHVTRVAWLNR 68
+ L +L L ++ G+ +S + P DN TV +G++ATL C ID VTRVAWLNR
Sbjct: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNR 71
Query: 69 SNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI 128
S ILYAGND+W DPRV LL NT ++SI I V + DEG YTCS QT + P T++V+LI
Sbjct: 72 STILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
Query: 129 VHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRD---GFTSEGEILEISDI 185
V V +IV ISS +++NEG N++L C+A GRPEPTVTWR + GF SE E LEI I
Sbjct: 132 VQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGI 191
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPP 245
R Q+G+YEC N V +AP RRV VTVNYPP I++ +G+ L+CEA AVP
Sbjct: 192 TREQSGDYECSASNDV-AAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPS 250
Query: 246 ADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMR 305
A+FQWYKDD+ L G +G+KV+ S L+F NVS YGNYTC A+N+LG ++AS+
Sbjct: 251 AEFQWYKDDKRLIEG-KKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIM 309
Query: 306 L 306
L
Sbjct: 310 L 310
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 259 bits (662), Expect = 2e-69
Identities = 136/304 (44%), Positives = 192/304 (63%), Gaps = 7/304 (2%)
Query: 15 AAALAGLAVISRGLL--SQSLEFNSPA-DNYTVCEGDNATLSCFIDEHVTRVAWLNRSNI 71
AA L L + L QS++F A DN V +GD A L C++++ ++ AWLNRS+I
Sbjct: 18 AAVLLSLCCLLPSCLPAGQSVDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSI 77
Query: 72 LYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHV 131
++AG D+W+ DPRV + ++S+ I V + D+G YTCS QT+H P T QV+L V V
Sbjct: 78 IFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQV 137
Query: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFT--SEGEILEISDIQRGQ 189
P +I +IS+ +TVNEG NV L CLA G+PEP+++WR + G+ L+I I R Q
Sbjct: 138 PPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQ 197
Query: 190 AGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQ 249
AGEYEC N V S PD R+V V VN+ PTI ++ S GR+ L+RCE VPP F+
Sbjct: 198 AGEYECSAENDV-SFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFE 256
Query: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRP 309
WYK ++ L +G +G+ +Q TRS+L NV+ H+GNYTC AAN+LG ++AS+ L P
Sbjct: 257 WYKGEKKLFNG-QQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPP 315
Query: 310 GSLE 313
+ +
Sbjct: 316 STAQ 319
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 97.4 bits (241), Expect = 2e-20
Identities = 62/235 (26%), Positives = 97/235 (41%), Gaps = 17/235 (7%)
Query: 89 INTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGG 148
I + + + I +V DE Y C + + ++L V +I + + +
Sbjct: 264 IFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEE 323
Query: 149 NVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILE---------------ISDIQRGQAGEY 193
V L C A G P P++TWR +SE + L+ + IQ AGEY
Sbjct: 324 QVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEY 383
Query: 194 ECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKD 253
C N + DS+ + + V Y P + + T G + CE A P A W++D
Sbjct: 384 ICTASNTIGQ--DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRD 441
Query: 254 DRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR 308
+LL S +K+ + S L S +GNY C A NR+G S L++
Sbjct: 442 GQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496
Score = 71.2 bits (173), Expect = 1e-12
Identities = 77/298 (25%), Positives = 116/298 (38%), Gaps = 35/298 (11%)
Query: 31 QSLEFNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLI 89
Q L F + EG++A + C + + + W ++ + D VR ++
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKD-------VRFIV 168
Query: 90 NTPEEFSILITEVGLGDEGLYTCSFQ--TRHQPYTTQVYLIVHVPARIVNISSPV--TVN 145
+ I + DEG Y C + R + + +IV+VP I + V T N
Sbjct: 169 LSNNYLQI--RGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATAN 226
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDG-------------FTSEGEILEISDIQRGQAGE 192
G +V L+C A G PEPT++W +DG F+ + L I + + E
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSW--TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAE 284
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTITDV-TSARTALGRAALLRCEAMAVPPADFQWY 251
Y C+ N + + + V P IT V L L CEA P W
Sbjct: 285 YICIAEN--KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR 342
Query: 252 KDDRLLSS--GTAEGLKVQTERTR-SMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
R +SS T +G V R S L ++ G Y C A+N +G S SM L
Sbjct: 343 TSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 400
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 16/237 (6%)
Query: 84 RVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV--NISSP 141
R+ ++ N ++ I + D G+Y C T ++ + V + +++ N +P
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQL-RDGFTSE--------GEILEISDIQRGQAGE 192
EG + ++C V PT+ W+ RD + L+I I++ G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQ 249
Y C + + + V VN PPTI ++ +A LG++ L C+A P
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 246
Query: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
W KD + + + ++ + S L V Y C A N+ G A++ L
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDS-SQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 97.4 bits (241), Expect = 2e-20
Identities = 62/235 (26%), Positives = 97/235 (41%), Gaps = 17/235 (7%)
Query: 89 INTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGG 148
I + + + I +V DE Y C + + ++L V +I + + +
Sbjct: 264 IFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEE 323
Query: 149 NVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILE---------------ISDIQRGQAGEY 193
V L C A G P P++TWR +SE + L+ + IQ AGEY
Sbjct: 324 QVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEY 383
Query: 194 ECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKD 253
C N + DS+ + + V Y P + + T G + CE A P A W++D
Sbjct: 384 ICTASNTIGQ--DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRD 441
Query: 254 DRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLR 308
+LL S +K+ + S L S +GNY C A NR+G S L++
Sbjct: 442 GQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496
Score = 71.2 bits (173), Expect = 1e-12
Identities = 77/298 (25%), Positives = 116/298 (38%), Gaps = 35/298 (11%)
Query: 31 QSLEFNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLI 89
Q L F + EG++A + C + + + W ++ + D VR ++
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKD-------VRFIV 168
Query: 90 NTPEEFSILITEVGLGDEGLYTCSFQ--TRHQPYTTQVYLIVHVPARIVNISSPV--TVN 145
+ I + DEG Y C + R + + +IV+VP I + V T N
Sbjct: 169 LSNNYLQI--RGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATAN 226
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDG-------------FTSEGEILEISDIQRGQAGE 192
G +V L+C A G PEPT++W +DG F+ + L I + + E
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSW--TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAE 284
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTITDV-TSARTALGRAALLRCEAMAVPPADFQWY 251
Y C+ N + + + V P IT V L L CEA P W
Sbjct: 285 YICIAEN--KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR 342
Query: 252 KDDRLLSS--GTAEGLKVQTERTR-SMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
R +SS T +G V R S L ++ G Y C A+N +G S SM L
Sbjct: 343 TSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL 400
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 16/237 (6%)
Query: 84 RVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV--NISSP 141
R+ ++ N ++ I + D G+Y C T ++ + V + +++ N +P
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQL-RDGFTSE--------GEILEISDIQRGQAGE 192
EG + ++C V PT+ W+ RD + L+I I++ G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQ 249
Y C + + + V VN PPTI ++ +A LG++ L C+A P
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 246
Query: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
W KD + + + ++ + S L V Y C A N+ G A++ L
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDS-SQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 92.4 bits (228), Expect = 5e-19
Identities = 79/278 (28%), Positives = 114/278 (41%), Gaps = 28/278 (10%)
Query: 38 PADNYTVCEGDNATLSC-FIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS 96
PA N TV G+ A LSC + E + W+ +L A S RV L + E S
Sbjct: 405 PAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPA------STGRVAQLADLSLEIS 458
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+I D G Y C + V+L+V ++ +S ++G V + C A
Sbjct: 459 GIIPT----DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA 514
Query: 157 VGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
G P P ++W + + I L I + AG Y C N V + D
Sbjct: 515 SGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT--DQET 572
Query: 210 VLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
V + PP+++ V + A+G A+L CEA VPP WY+ G E +
Sbjct: 573 VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR-------GGLEMILAP 625
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L R G YTCRA N LG +SA ++L
Sbjct: 626 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 663
Score = 75.5 bits (184), Expect = 6e-14
Identities = 83/329 (25%), Positives = 129/329 (39%), Gaps = 30/329 (9%)
Query: 4 PAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVT-R 62
P G R + +A+ A L+ ++ + + + +G +SC + T
Sbjct: 462 PTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPH 521
Query: 63 VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYT 122
++W S L D R I+ + +++I V D G Y+C
Sbjct: 522 ISWSRESQALQ-------EDSR----IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQ 570
Query: 123 TQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQ------LRDGFTSE 176
V L P + +++ V V G L+C A G P P V W + L +S
Sbjct: 571 ETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 630
Query: 177 GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTA-LGRAAL 235
G+ L I Q AG Y C N + A S + + V + P +T++ T LGR+AL
Sbjct: 631 GK-LRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQLTELPRDVTVELGRSAL 687
Query: 236 LRCEAMAVPPADFQWYKDDRL---LSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCR 292
L C A PP W + D L G G + + + +L F +V+ Y C
Sbjct: 688 LACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSR-QPDSGVLFFESVAPEDQAPYVCE 746
Query: 293 AANRLGASSASMRLL----RPGSLENSAP 317
A N G A RL+ P + +SAP
Sbjct: 747 ARNVFGKVQAEARLIVTGHAPPQIASSAP 775
Score = 75.1 bits (183), Expect = 8e-14
Identities = 73/229 (31%), Positives = 94/229 (41%), Gaps = 23/229 (10%)
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIV--HVPARIVNISSPVTVNEGGN 149
P+ + V D+ Y C + + LIV H P +I + + V V EG
Sbjct: 725 PDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQP 784
Query: 150 VNLLCLAV-GRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTH 198
V+L C+ + GRP P W L+DG ++G L + + AG Y CV
Sbjct: 785 VSLPCIVLAGRPLPERHW--LKDGRPLPPGSRHSIRADGS-LHLDRALQEHAGRYSCVAT 841
Query: 199 NGVNSAPDSRRVLVTVNYPPTI-TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
N S R V + V PP I T T G A L C A VP W K+ L
Sbjct: 842 NTAGS--QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL 899
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+S V E T LL A SA+ G Y C A N +G SS MRL
Sbjct: 900 TS-RGPHYNVSKEGT---LLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 944
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/218 (26%), Positives = 83/218 (38%), Gaps = 21/218 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G YTC + ++ L V ++ + VTV G + L C A GRP PTVT
Sbjct: 642 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 701
Query: 166 WRQ-------LRDGF-------TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL 211
WR+ LR G + +L + Y C N R++
Sbjct: 702 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 761
Query: 212 VTVNYPPTI-TDVTSARTALGRAALLRCEAMAVPP-ADFQWYKDDRLLSSGTAEGLKVQT 269
VT + PP I + + R G+ L C +A P + W KD R L G+ +
Sbjct: 762 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSI---- 817
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
R L H G Y+C A N G+ + L+
Sbjct: 818 -RADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELV 854
Score = 70.5 bits (171), Expect = 2e-12
Identities = 64/212 (30%), Positives = 86/212 (40%), Gaps = 26/212 (12%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR 167
G Y+C V L+V VP RI ++ NEG +L C+A G P PT+TW
Sbjct: 834 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 893
Query: 168 QLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPT 219
+ + TS G L I+ AG Y C N V + S+ + ++VN P
Sbjct: 894 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFS--SQEMRLSVNTKPR 951
Query: 220 ITDVTSARTA---------LGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE-GLKVQT 269
I + +R A G L CEA PP W KD R + T GL
Sbjct: 952 I-HMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGL---- 1006
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASS 301
L A V G+Y C A+N G++S
Sbjct: 1007 -LPSGSLRLAQVQVGDSGHYECTASNPAGSAS 1037
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 14/216 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +EG Y C+ +R + ++V P + + VTV+ G L C +G
Sbjct: 366 ILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG 425
Query: 159 RPEPTVTW-RQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
+TW R R S G + LEIS I G Y+CV N N +
Sbjct: 426 EAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTRASVW 484
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
L+ P +S + G + C A P W ++ + L E ++ +
Sbjct: 485 LLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQ----EDSRIHVD 540
Query: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L+ V+ GNY+C+A N +G ++ L
Sbjct: 541 -AQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 575
Score = 54.7 bits (130), Expect = 1e-07
Identities = 47/183 (25%), Positives = 71/183 (38%), Gaps = 28/183 (15%)
Query: 39 ADNYTVCEGDNATLSCFIDE-HVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSI 97
A ++ EG A+L C + W +N L + + N +E ++
Sbjct: 865 ATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHY----------NVSKEGTL 914
Query: 98 LITEVGLGDEGLYTCS------FQTRHQPYTTQVYLIVHV-PARIVNISSPVTVNEGGNV 150
LI + D G Y C+ F ++ + +H+ +R N+ VT G V
Sbjct: 915 LIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEV 974
Query: 151 NLLCLAVGRPEPTVTWRQ---------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGV 201
L C A G P P VTW + R G G L ++ +Q G +G YEC N
Sbjct: 975 TLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS-LRLAQVQVGDSGHYECTASNPA 1033
Query: 202 NSA 204
SA
Sbjct: 1034 GSA 1036
Score = 49.7 bits (117), Expect = 4e-06
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 167 RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSA 226
R ++ S EIL S + + G YEC + + +++VT + PP + +
Sbjct: 354 RHFQESGNSSWEILRAS---KAEEGTYECTAVSRAGTGRAKAQIVVT-DPPPQLVPAPNV 409
Query: 227 RTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHY 286
+ G A+L C + P + W +D R+L + T + L + +
Sbjct: 410 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGR----VAQLADLSLEISGIIPTDG 465
Query: 287 GNYTCRAANRLGASSASMRLL 307
G Y C A+N G + AS+ LL
Sbjct: 466 GRYQCVASNANGVTRASVWLL 486
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 92.4 bits (228), Expect = 5e-19
Identities = 79/278 (28%), Positives = 114/278 (41%), Gaps = 28/278 (10%)
Query: 38 PADNYTVCEGDNATLSC-FIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS 96
PA N TV G+ A LSC + E + W+ +L A S RV L + E S
Sbjct: 522 PAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPA------STGRVAQLADLSLEIS 575
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+I D G Y C + V+L+V ++ +S ++G V + C A
Sbjct: 576 GIIPT----DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA 631
Query: 157 VGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
G P P ++W + + I L I + AG Y C N V + D
Sbjct: 632 SGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT--DQET 689
Query: 210 VLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
V + PP+++ V + A+G A+L CEA VPP WY+ G E +
Sbjct: 690 VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR-------GGLEMILAP 742
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L R G YTCRA N LG +SA ++L
Sbjct: 743 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 780
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/237 (29%), Positives = 103/237 (43%), Gaps = 27/237 (11%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP---VTVNEGGNVNLL 153
+ + + L EG YTC + + L VHVP +I P V+V + G L
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 2279
Query: 154 CLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
C A G+P PTVTW RDG ++G+ L + Q G Y CV N
Sbjct: 2280 CNATGKPPPTVTWE--RDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 2337
Query: 204 APDSRRVLVTVNYPPTITD----VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSS 259
A R+ ++V PP + +T+ AL L CEAM +PP +W++ + +S
Sbjct: 2338 A--ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSP 2395
Query: 260 GTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLEN 314
G L ML + G Y+C A+N G + + S+ +L P S+EN
Sbjct: 2396 GEDTYLLA----GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIEN 2448
Score = 87.4 bits (215), Expect = 2e-17
Identities = 79/304 (25%), Positives = 121/304 (39%), Gaps = 34/304 (11%)
Query: 41 NYTVCEGDNATLSCFIDEH-VTRVAWLNRSNIL--------YAGNDRWTSDPRVRLLINT 91
N + G + TL C + V + WL + ++ Y + W RLL
Sbjct: 1309 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLL--- 1365
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVN--EGGN 149
E S+ + GD GLY+C + + +L+V P ++ + V G +
Sbjct: 1366 DEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGAD 1425
Query: 150 VNLLCLAVGRPEPTVTWRQLRDGFT---------SEGEILEISDIQRGQAGEYECVTHNG 200
V L C G P P V W + R +G++L I+ G G Y+CV +
Sbjct: 1426 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP 1485
Query: 201 VNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
+R + V+ PPTI + L CEA VP + W+KD LL
Sbjct: 1486 AGQ--QARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 1543
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENS 315
+ T KV R L + G YTC+A+N +GA+ + RL P ++E +
Sbjct: 1544 PTST----KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGA 1599
Query: 316 APRP 319
RP
Sbjct: 1600 GGRP 1603
Score = 80.5 bits (197), Expect = 2e-15
Identities = 67/209 (32%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G Y C + + L+V VP I N ++ EG + L C A G PEP +T
Sbjct: 4011 DAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT 4070
Query: 166 WRQLRDG---------FTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV 214
W +DG FT + GE+L + +++ AG Y C N V A RRV +T+
Sbjct: 4071 WD--KDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRA--RRRVHLTI 4125
Query: 215 NYPPTITDVTSART-ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
P T + R+ LG LRC A P W +DR ++ G +E +
Sbjct: 4126 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSE------QDGG 4179
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSA 302
S L A VS G Y C A NR+G + A
Sbjct: 4180 STLQRAAVSREDSGTYVCWAENRVGRTQA 4208
Score = 80.1 bits (196), Expect = 3e-15
Identities = 66/210 (31%), Positives = 85/210 (40%), Gaps = 14/210 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +V L DEG+YTC+ +V L V VP I V E +V L CLA G
Sbjct: 1852 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 1911
Query: 159 RPEPTVTWRQLRDGFTS--------EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
P P V+W + +S +G +L I Q AG Y CV N S R
Sbjct: 1912 VPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST--ELRY 1969
Query: 211 LVTVNYPPTITDVTS--ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
+ VN PP IT S + L C A P W KD +S GL+V
Sbjct: 1970 GLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVF 2029
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLG 298
+L A+ A G Y+C A + +G
Sbjct: 2030 P--GGRVLTLASARASDSGRYSCVAVSAVG 2057
Score = 79.0 bits (193), Expect = 6e-15
Identities = 83/297 (27%), Positives = 110/297 (37%), Gaps = 35/297 (11%)
Query: 38 PADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS- 96
P D V GD A LSC D L W D + +L +
Sbjct: 3038 PQDAVLVRVGDKAVLSCETDA-------------LPEPTVTWYKDGQPLVLAQRTQALRG 3084
Query: 97 ---ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGN-VNL 152
+ I E + D+GLY+C L V VP N + G+ + L
Sbjct: 3085 GQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVL 3144
Query: 153 LCLAVGRPEPTVTWRQLR--------DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204
C G P PTVTW + R G S G L++S +Q QAG Y CV N A
Sbjct: 3145 TCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN--TQA 3202
Query: 205 PDSRRVLVTVNYPPTITDVTSAR---TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ +V V P I AR G+ L CEA PP D W KD L
Sbjct: 3203 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 3262
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSA 316
L+ + L+ + A G YTC A N G A ++ +L P +++ A
Sbjct: 3263 GPHLRFYLD--GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 3317
Score = 77.0 bits (188), Expect = 2e-14
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 26/224 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV---NISSPVTVNEGGNVNLLCL 155
I + L D G Y C + L V+VP RI ++ PV VN V L C
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN 2000
Query: 156 AVGRPEPTVTWRQLRDGFTSE------------GEILEISDIQRGQAGEYECVTHNGVNS 203
A G P PT+ W L+DG G +L ++ + +G Y CV + V
Sbjct: 2001 ATGAPSPTLMW--LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 2058
Query: 204 APDSRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
D + V++ V+ PP+I + + + L C++ A+PP W+KD R L
Sbjct: 2059 --DRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPG 2116
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V +++L G+YTC A N+ G S L
Sbjct: 2117 ----VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNL 2156
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/229 (28%), Positives = 91/229 (39%), Gaps = 23/229 (10%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVN----ISSPVTVNEGGNVNLLCLAVGRPEPT 163
G Y+C L+V P I+ + VTVN V+L C A+G P PT
Sbjct: 2817 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPT 2876
Query: 164 VTWRQLRDGFT--------SEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
++W Q F+ +G++L++S + A Y CV N SA + + V
Sbjct: 2877 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA--EKLFTLRVQ 2934
Query: 216 YPPTIT--DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP I D+ L + L C+ A P + WYKD + LS G L T
Sbjct: 2935 VPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH--- 2991
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENSAPRPP 320
L G YTC A N G ++L L P + APR P
Sbjct: 2992 -TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAF-RQAPRGP 3038
Score = 75.5 bits (184), Expect = 6e-14
Identities = 83/329 (25%), Positives = 129/329 (39%), Gaps = 30/329 (9%)
Query: 4 PAPGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVT-R 62
P G R + +A+ A L+ ++ + + + +G +SC + T
Sbjct: 579 PTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPH 638
Query: 63 VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYT 122
++W S L D R I+ + +++I V D G Y+C
Sbjct: 639 ISWSRESQALQ-------EDSR----IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQ 687
Query: 123 TQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQ------LRDGFTSE 176
V L P + +++ V V G L+C A G P P V W + L +S
Sbjct: 688 ETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 747
Query: 177 GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTA-LGRAAL 235
G+ L I Q AG Y C N + A S + + V + P +T++ T LGR+AL
Sbjct: 748 GK-LRIPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQLTELPRDVTVELGRSAL 804
Query: 236 LRCEAMAVPPADFQWYKDDRL---LSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCR 292
L C A PP W + D L G G + + + +L F +V+ Y C
Sbjct: 805 LACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSR-QPDSGVLFFESVAPEDQAPYVCE 863
Query: 293 AANRLGASSASMRLL----RPGSLENSAP 317
A N G A RL+ P + +SAP
Sbjct: 864 ARNVFGKVQAEARLIVTGHAPPQIASSAP 892
Score = 75.1 bits (183), Expect = 8e-14
Identities = 73/229 (31%), Positives = 94/229 (41%), Gaps = 23/229 (10%)
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIV--HVPARIVNISSPVTVNEGGN 149
P+ + V D+ Y C + + LIV H P +I + + V V EG
Sbjct: 842 PDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQP 901
Query: 150 VNLLCLAV-GRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTH 198
V+L C+ + GRP P W L+DG ++G L + + AG Y CV
Sbjct: 902 VSLPCIVLAGRPLPERHW--LKDGRPLPPGSRHSIRADGS-LHLDRALQEHAGRYSCVAT 958
Query: 199 NGVNSAPDSRRVLVTVNYPPTI-TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
N S R V + V PP I T T G A L C A VP W K+ L
Sbjct: 959 NTAGS--QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL 1016
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+S V E T LL A SA+ G Y C A N +G SS MRL
Sbjct: 1017 TS-RGPHYNVSKEGT---LLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 1061
Score = 75.1 bits (183), Expect = 8e-14
Identities = 63/207 (30%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR 167
G YTCS + V+L V + + S V V L C A G P PT+TW+
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 3982
Query: 168 Q----LRDGFTSE---GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI 220
+ + G +++ G L I+ AG Y C+ N SA R++V V PP I
Sbjct: 3983 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV--PPVI 4040
Query: 221 TD-VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFA 279
+ + T G A L C+A P + W KD + +S AEG T + LL
Sbjct: 4041 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG--AEG--KFTIQPSGELLVK 4096
Query: 280 NVSARHYGNYTCRAANRLGASSASMRL 306
N+ + G YTC A N +G + + L
Sbjct: 4097 NLEGQDAGTYTCTAENAVGRARRRVHL 4123
Score = 74.7 bits (182), Expect = 1e-13
Identities = 61/234 (26%), Positives = 92/234 (39%), Gaps = 12/234 (5%)
Query: 79 WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI 138
W D L + + S+ + VG GD G Y+C + L V P I +
Sbjct: 3440 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 3499
Query: 139 SSP--VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS-EGEILEISDIQRGQAGEYEC 195
P +++ G + LLC A G P+P +TW + T E ++ AG Y C
Sbjct: 3500 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 3559
Query: 196 VTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRA---ALLRCEAMAVPPADFQWYK 252
+ + + S R V V PP I R +G A +L C A P W++
Sbjct: 3560 LAESPAGAIEKSFR--VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 3617
Query: 253 DDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
D +L E Q L +S G+Y+C A N G++S + R+
Sbjct: 3618 DGIVLQ----EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 3667
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/233 (26%), Positives = 89/233 (38%), Gaps = 18/233 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
++L+T G D + C + VHVP I + + TV V L C
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH 3879
Query: 156 AVGRPEPTVTWRQLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVNSAPDS 207
+ G P PTV+W + + G LEI AG Y C N A
Sbjct: 3880 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVA--H 3937
Query: 208 RRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+ V +TV P + + S R LL CEA +P W K+ +++G + +
Sbjct: 3938 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV- 3996
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL--RPGSLENSAP 317
L A+ S GNY C A N G++ RL+ P +EN P
Sbjct: 3997 ----LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 4045
Score = 72.4 bits (176), Expect = 5e-13
Identities = 61/218 (27%), Positives = 93/218 (42%), Gaps = 12/218 (5%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
S+ + +V +GD G Y C+ + + L V VP ++ + V G ++L C+
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCV 1142
Query: 156 AVGRPEPTVTWRQLRDGFTSEGE----ILEISDIQRGQAGEYECVTHN--GVNSAPDSRR 209
A G PEP ++W +DG +G + + I+ AG Y C N GV++ R
Sbjct: 1143 AEGNPEPQLSWS--KDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELR 1200
Query: 210 VLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQT 269
VL ++ T R A G A L C A P W K SS G
Sbjct: 1201 VLEPPHWGADETSGLLERVA-GENASLPCPARGTPKPQVTWRKGP---SSEPLHGQPGVA 1256
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
L A+VS G+Y C+A N +G++S +L+
Sbjct: 1257 VLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLV 1294
Score = 72.4 bits (176), Expect = 5e-13
Identities = 69/237 (29%), Positives = 100/237 (42%), Gaps = 28/237 (11%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI--VNISSPVTVNEGGNVNLL 153
++ I++V L D G++TC + L V VP + V + V V G V L
Sbjct: 3368 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 3427
Query: 154 CLAVGRPEPTVTWRQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
C A G P P V+W ++DG +G L++ + G +G Y CV V+ A ++
Sbjct: 3428 CEARGVPLPLVSW--MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV---AVSEAGEA 3482
Query: 208 RR-VLVTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
RR +TV PP I D T G L C+A P + W+KD + L+
Sbjct: 3483 RRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR---- 3538
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPP 320
L+ + TR + R G YTC A + GA S R+ PR P
Sbjct: 3539 -LENNSRATRVL------RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGP 3588
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/218 (26%), Positives = 83/218 (38%), Gaps = 21/218 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G YTC + ++ L V ++ + VTV G + L C A GRP PTVT
Sbjct: 759 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 818
Query: 166 WRQ-------LRDGF-------TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL 211
WR+ LR G + +L + Y C N R++
Sbjct: 819 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 878
Query: 212 VTVNYPPTI-TDVTSARTALGRAALLRCEAMAVPP-ADFQWYKDDRLLSSGTAEGLKVQT 269
VT + PP I + + R G+ L C +A P + W KD R L G+ +
Sbjct: 879 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSI---- 934
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
R L H G Y+C A N G+ + L+
Sbjct: 935 -RADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELV 971
Score = 67.4 bits (163), Expect = 2e-11
Identities = 71/271 (26%), Positives = 93/271 (34%), Gaps = 31/271 (11%)
Query: 40 DNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSIL 98
+ T + +L C + H V W S L G + V LL P ++
Sbjct: 2945 EQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE-------VFLL---PGTHTLQ 2994
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI----SSPVTVNEGGNVNLLC 154
+ L D G+YTC V L V VP V V G L C
Sbjct: 2995 LGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 3054
Query: 155 LAVGRPEPTVTWRQ--------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
PEPTVTW + R G+ LEI + Q G Y C N A
Sbjct: 3055 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEA-- 3112
Query: 207 SRRVLVTVNYPPTITD--VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
R +TV PPT + + G +L C+ VP W KD + S G
Sbjct: 3113 VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHG 3172
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAAN 295
+ + R L + + G YTC A N
Sbjct: 3173 VVSRGGR----LQLSRLQPAQAGTYTCVAEN 3199
Score = 66.2 bits (160), Expect = 4e-11
Identities = 58/237 (24%), Positives = 89/237 (37%), Gaps = 24/237 (10%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVN--ISSPVTVNEGGNVNLLCLA 156
+T+ D GLY+C + V VP I N + + V +G +L+C
Sbjct: 2410 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 2469
Query: 157 VGRPEPTVTW----RQLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
G P+P +TW R L G + +G +L++ AG Y C+ N V ++
Sbjct: 2470 TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE--KTK 2527
Query: 209 RVLVTVNYPPTI------TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
++V PTI + + L CEA+A P + W KD +
Sbjct: 2528 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASR- 2586
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSAP 317
+Q L N G YTC N LG + + +L P S+ P
Sbjct: 2587 ---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 2640
Score = 65.1 bits (157), Expect = 9e-11
Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 31/221 (14%)
Query: 106 DEGLYTCSF--QTRHQP--YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
D G YTC Q H Y V++ P R S +TV EG +L C G P
Sbjct: 2135 DAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRE---SHTLTVREGHPTSLSCECRGVPF 2191
Query: 162 PTVTWRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
P ++WR +DG ++ G +L + Q Q G Y C N V ++ S+
Sbjct: 2192 PKISWR--KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS--SQD 2247
Query: 210 VLVTVNYPPTIT----DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+ + V+ PP I T A L C A PP W +D + + G GL
Sbjct: 2248 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGL 2305
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++Q + L A H G Y+C A N G + L
Sbjct: 2306 QLQNQ--GQSLHVERAQAAHTGRYSCVAENLAGRAERKFEL 2344
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/240 (25%), Positives = 89/240 (37%), Gaps = 46/240 (19%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-------SPVTVNEGGNVNLLCLAVG 158
D G YTC ++ V +P I V + L C +
Sbjct: 2606 DAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWA 2665
Query: 159 RPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
P PT+ W +DG EG +L+I Q +G Y CV N
Sbjct: 2666 VPPPTIRW--YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 2723
Query: 209 RVLVTVNYPPT---ITDVTSARTALGRA------------------ALLRCEAMAVPPAD 247
VL+ V PP + D ++A L R A L C+ A+PP D
Sbjct: 2724 NVLIQV--PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPD 2781
Query: 248 FQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
WY++D+ LS+G +V + +L V A + G Y+C+A+N +G LL
Sbjct: 2782 LTWYREDQPLSAGD----EVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELL 2837
Score = 63.9 bits (154), Expect = 2e-10
Identities = 64/263 (24%), Positives = 93/263 (35%), Gaps = 42/263 (15%)
Query: 79 WTSDPRVRLLINTP-----EEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPA 133
W P L P EE S+ + V D G Y C + + L+V+VP
Sbjct: 1240 WRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPP 1299
Query: 134 RIVNISSPVTVN--EGGNVNLLCLAVGRPEPTVTWRQLRDG------------------- 172
I V+ G ++ L C A G P P + W L+D
Sbjct: 1300 SIREDGRKANVSGMAGQSLTLECDANGFPVPEIVW--LKDAQLVGVPLGWAGYGWDLGWG 1357
Query: 173 ------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSA 226
EG+ L IQ G +G Y C N +A +LV PP++ +A
Sbjct: 1358 QVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLT--PPSVLGAGAA 1415
Query: 227 RTALGRAAL---LRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSA 283
+ LG A L+C VP +W KD + + G G +Q + +L
Sbjct: 1416 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPG---GPHLQVQEDGQVLRITGSHV 1472
Query: 284 RHYGNYTCRAANRLGASSASMRL 306
G Y C A + G + +L
Sbjct: 1473 GDEGRYQCVAFSPAGQQARDFQL 1495
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/231 (27%), Positives = 88/231 (38%), Gaps = 33/231 (14%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS-PVTVNE--GGNVNLLCLAVGRPEP 162
D G+YTC L V+VP I P V G V L C+A G P P
Sbjct: 1567 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 1626
Query: 163 TVTW--------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL--- 211
T++W ++G +L + +G Y CV S+P VL
Sbjct: 1627 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-----SSPAGEAVLQYS 1681
Query: 212 VTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK-V 267
V V PP + + T +G+ L C+A P QW ++ R AE L V
Sbjct: 1682 VEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGR-----PAEELAGV 1736
Query: 268 QTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL-----LRPGSLE 313
Q + L +V H G + C+A N G + A + + PG LE
Sbjct: 1737 QVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 1787
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 14/216 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +EG Y C+ +R + ++V P + + VTV+ G L C +G
Sbjct: 483 ILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG 542
Query: 159 RPEPTVTW-RQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
+TW R R S G + LEIS I G Y+CV N N +
Sbjct: 543 EAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTRASVW 601
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
L+ P +S + G + C A P W ++ + L E ++ +
Sbjct: 602 LLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQ----EDSRIHVD 657
Query: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L+ V+ GNY+C+A N +G ++ L
Sbjct: 658 -AQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 692
Score = 58.5 bits (140), Expect = 8e-09
Identities = 59/222 (26%), Positives = 88/222 (39%), Gaps = 22/222 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHV---PARIVNISSPVTVNEGGNVNLLCLAVGRPEP 162
D G Y C + R TQ VHV P S + GG++ L C+ G P P
Sbjct: 4191 DSGTYVCWAENRVG--RTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 4248
Query: 163 TVTWRQLRDGFTSEGEILE---------ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVT 213
+ W ++DG G L I +R AG Y+C+ N + A +LV
Sbjct: 4249 DIHW--IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV-ILVL 4305
Query: 214 VNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
+ P + G LRC+A P +W + + L + +++T
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR----RLRTLPDG 4361
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENS 315
S+ L NV G Y C A N LG+++A L+ G + S
Sbjct: 4362 SLWL-ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGS 4402
Score = 55.5 bits (132), Expect = 7e-08
Identities = 61/264 (23%), Positives = 85/264 (32%), Gaps = 72/264 (27%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR 167
G Y+C V L+V VP RI ++ NEG +L C+A G P PT+TW
Sbjct: 951 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 1010
Query: 168 QLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVN----------------- 202
+ + TS G L I+ AG Y C N V
Sbjct: 1011 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSK 1070
Query: 203 ----------------------------------SAPDSRRVLVTVNYPPTITDVTSA-R 227
+ S R ++ V PP + +
Sbjct: 1071 YVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLK 1130
Query: 228 TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYG 287
+G A L C A P W KD G+ +Q + + FA + G
Sbjct: 1131 VLVGEALDLNCVAEGNPEPQLSWSKD----------GVVLQGRGPQGSVHFAAIRTSDAG 1180
Query: 288 NYTCRAANRLG--ASSASMRLLRP 309
Y C A+N G A +R+L P
Sbjct: 1181 RYRCEASNSAGVDAWEVELRVLEP 1204
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/204 (28%), Positives = 77/204 (37%), Gaps = 17/204 (8%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLL--CLAVGRPEPT 163
D G Y+C+ R+ +T V V + S P VN N L C A G P P
Sbjct: 3646 DSGDYSCT--ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPL 3703
Query: 164 VTWRQLR---DGFTSEGEI-----LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
V+WR+ R D + EI L I + AG Y C+ N S R + V
Sbjct: 3704 VSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL-- 3761
Query: 216 YPPTITDVTSARTALGRA-ALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
PP I S T ALL CEA P W+KD + L +G +
Sbjct: 3762 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG--AYRLLPSN 3819
Query: 275 MLLFANVSARHYGNYTCRAANRLG 298
LL + + C +N +G
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSNEVG 3843
Score = 51.2 bits (121), Expect = 1e-06
Identities = 37/130 (28%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-SPVTVNEGGNVNLLC 154
S+ I D G Y C + +V ++V A + + +TV G +V L C
Sbjct: 4272 SLTIHRTERDDAGRYQCLAENE-MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 4330
Query: 155 LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDS 207
A G P PT+ W Q + + L + +++ G AG Y+CV HN + SA +
Sbjct: 4331 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA-TA 4389
Query: 208 RRVLVTVNYP 217
R LV P
Sbjct: 4390 RAFLVVRGEP 4399
Score = 50.1 bits (118), Expect = 3e-06
Identities = 57/264 (21%), Positives = 90/264 (34%), Gaps = 26/264 (9%)
Query: 46 EGDNATLSCFI-DEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGL 104
EG +A L C + W + ++T P LL+ E
Sbjct: 4051 EGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEG---------- 4100
Query: 105 GDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTV 164
D G YTC+ + +V+L + V + ++ G + L C A G P P +
Sbjct: 4101 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 4160
Query: 165 TW----RQLRDGFTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218
W R + +G + + G L+ + + R +G Y C N V V V P
Sbjct: 4161 GWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAP 4218
Query: 219 TITDVTSARTA--LGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSML 276
+ + +G + L C P D W KD L G ++ + L
Sbjct: 4219 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-----RGSHLRHQLQNGSL 4273
Query: 277 LFANVSARHYGNYTCRAANRLGAS 300
G Y C A N +G +
Sbjct: 4274 TIHRTERDDAGRYQCLAENEMGVA 4297
Score = 49.7 bits (117), Expect = 4e-06
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 167 RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSA 226
R ++ S EIL S + + G YEC + + +++VT + PP + +
Sbjct: 471 RHFQESGNSSWEILRAS---KAEEGTYECTAVSRAGTGRAKAQIVVT-DPPPQLVPAPNV 526
Query: 227 RTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHY 286
+ G A+L C + P + W +D R+L + T + L + +
Sbjct: 527 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGR----VAQLADLSLEISGIIPTDG 582
Query: 287 GNYTCRAANRLGASSASMRLL 307
G Y C A+N G + AS+ LL
Sbjct: 583 GRYQCVASNANGVTRASVWLL 603
Score = 49.3 bits (116), Expect = 5e-06
Identities = 57/234 (24%), Positives = 86/234 (36%), Gaps = 25/234 (10%)
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS--PVTVNEGGNVNLLCLAVGRP 160
G GLY+C + Q + V VP +++ VT G + L C A G P
Sbjct: 1658 GEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP 1717
Query: 161 EPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
PT+ W L++G S+G L I ++ +G + C N +A V
Sbjct: 1718 VPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEV 1775
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDR------LLSSGTAEG 264
V + P + +V + G A PP W + S G+ G
Sbjct: 1776 SVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWG 1835
Query: 265 LKVQTERTRSM---LLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLE 313
S+ L V R G YTC A N G S ++++L P ++E
Sbjct: 1836 EPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 1889
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 92.4 bits (228), Expect = 5e-19
Identities = 79/278 (28%), Positives = 114/278 (41%), Gaps = 28/278 (10%)
Query: 38 PADNYTVCEGDNATLSC-FIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS 96
PA N TV G+ A LSC + E + W+ +L A S RV L + E S
Sbjct: 521 PAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPA------STGRVAQLADLSLEIS 574
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+I D G Y C + V+L+V ++ +S ++G V + C A
Sbjct: 575 GIIPT----DGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA 630
Query: 157 VGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
G P P ++W + + I L I + AG Y C N V + D
Sbjct: 631 SGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT--DQET 688
Query: 210 VLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
V + PP+++ V + A+G A+L CEA VPP WY+ G E +
Sbjct: 689 VTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR-------GGLEMILAP 741
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L R G YTCRA N LG +SA ++L
Sbjct: 742 EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 779
Score = 60.8 bits (146), Expect = 2e-09
Identities = 52/216 (24%), Positives = 84/216 (38%), Gaps = 14/216 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +EG Y C+ +R + ++V P + + VTV+ G L C +G
Sbjct: 482 ILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLG 541
Query: 159 RPEPTVTW-RQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
+TW R R S G + LEIS I G Y+CV N N +
Sbjct: 542 EAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASN-ANGVTRASVW 600
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
L+ P +S + G + C A P W ++ + L E ++ +
Sbjct: 601 LLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQ----EDSRIHVD 656
Query: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L+ V+ GNY+C+A N +G ++ L
Sbjct: 657 -AQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTL 691
Score = 49.7 bits (117), Expect = 4e-06
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 8/141 (5%)
Query: 167 RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSA 226
R ++ S EIL S + + G YEC + + +++VT + PP + +
Sbjct: 470 RHFQESGNSSWEILRAS---KAEEGTYECTAVSRAGTGRAKAQIVVT-DPPPQLVPAPNV 525
Query: 227 RTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHY 286
+ G A+L C + P + W +D R+L + T + L + +
Sbjct: 526 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGR----VAQLADLSLEISGIIPTDG 581
Query: 287 GNYTCRAANRLGASSASMRLL 307
G Y C A+N G + AS+ LL
Sbjct: 582 GRYQCVASNANGVTRASVWLL 602
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 92.4 bits (228), Expect = 5e-19
Identities = 62/245 (25%), Positives = 96/245 (39%), Gaps = 27/245 (11%)
Query: 89 INTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGG 148
I + + + I +V DE Y C + + ++L V +I + + +
Sbjct: 264 IFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEE 323
Query: 149 NVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI-------------------------LEIS 183
V L C A G P P++TWR +SE + L +
Sbjct: 324 QVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLK 383
Query: 184 DIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAV 243
IQ AGEY C N + DS+ + + V Y P + + T G + CE A
Sbjct: 384 SIQYTDAGEYICTASNTIGQ--DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAY 441
Query: 244 PPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
P A W++D +LL S +K+ + S L S +GNY C A NR+G S
Sbjct: 442 PSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLE 501
Query: 304 MRLLR 308
L++
Sbjct: 502 FILVQ 506
Score = 67.4 bits (163), Expect = 2e-11
Identities = 77/308 (25%), Positives = 116/308 (37%), Gaps = 45/308 (14%)
Query: 31 QSLEFNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLI 89
Q L F + EG++A + C + + + W ++ + D VR ++
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKD-------VRFIV 168
Query: 90 NTPEEFSILITEVGLGDEGLYTCSFQ--TRHQPYTTQVYLIVHVPARIVNISSPV--TVN 145
+ I + DEG Y C + R + + +IV+VP I + V T N
Sbjct: 169 LSNNYLQI--RGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATAN 226
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDG-------------FTSEGEILEISDIQRGQAGE 192
G +V L+C A G PEPT++W +DG F+ + L I + + E
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSW--TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAE 284
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTITDV-TSARTALGRAALLRCEAMAVPPADFQWY 251
Y C+ N + + + V P IT V L L CEA P W
Sbjct: 285 YICIAEN--KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWR 342
Query: 252 KDDRLLSS------------GTAEGLKVQTERTR-SMLLFANVSARHYGNYTCRAANRLG 298
R +SS T +G V R S L ++ G Y C A+N +G
Sbjct: 343 TSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIG 402
Query: 299 ASSASMRL 306
S SM L
Sbjct: 403 QDSQSMYL 410
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 16/237 (6%)
Query: 84 RVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV--NISSP 141
R+ ++ N ++ I + D G+Y C T ++ + V + +++ N +P
Sbjct: 68 RISVVWNDDSSSTLTIYNANIDDAGIYKC-VVTGEDGSESEATVNVKIFQKLMFKNAPTP 126
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQL-RDGFTSE--------GEILEISDIQRGQAGE 192
EG + ++C V PT+ W+ RD + L+I I++ G
Sbjct: 127 QEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGT 186
Query: 193 YECVTHNGVNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQ 249
Y C + + + V VN PPTI ++ +A LG++ L C+A P
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 246
Query: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
W KD + + + ++ + S L V Y C A N+ G A++ L
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDS-SQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 91.3 bits (225), Expect = 1e-18
Identities = 75/277 (27%), Positives = 118/277 (42%), Gaps = 33/277 (11%)
Query: 44 VCEGDNATLSCFIDEHVT-----RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSIL 98
V G++A C HVT R+ W + + G + + + NTP +
Sbjct: 6282 VIAGESADFEC----HVTGAQPMRITWSKDNKEIRPGGNY-----TITCVGNTPH---LR 6329
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVN-ISSPVTVNEGGNVNLLCLAV 157
I +VG GD G YTC L V P + V + + +G ++ L C
Sbjct: 6330 ILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKIS 6389
Query: 158 GRPEPTVTW----RQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
G PE V+W +L + F + +L I++ +G+Y C HNGV A S
Sbjct: 6390 GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDA--S 6447
Query: 208 RRVLVTVNYPPTITDVTSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+TV PP T S AL G +L+CE PP + W KD + + + ++ K
Sbjct: 6448 CSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRN--SKKFK 6505
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
+ ++ + L N+ A G Y C+A N +G+ + S
Sbjct: 6506 ITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCS 6542
Score = 84.3 bits (207), Expect = 1e-16
Identities = 72/272 (26%), Positives = 106/272 (38%), Gaps = 33/272 (12%)
Query: 47 GDNATLSCFIDEHVT-----RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITE 101
G++ T C HVT ++ W + + G + ++ L+ NT ++ + +
Sbjct: 7226 GESGTFKC----HVTGTAPIKITWAKDNREIRPGGNY-----KMTLVENTA---TLTVLK 7273
Query: 102 VGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVT-VNEGGNVNLLCLAVGRP 160
VG GD G YTC + L V P R + P V + C G P
Sbjct: 7274 VGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSP 7333
Query: 161 EPTVTW----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
E V W + R F +LE+ ++ +G+Y C HN SA S +
Sbjct: 7334 EIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 7393
Query: 211 LVTVNYPPTITDVTSA-RTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQT 269
V PP T G L CE PP WYKD R L SG + K+ +
Sbjct: 7394 --KVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSG--KKYKIMS 7449
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASS 301
E + + NV A G Y C+A N +G+ +
Sbjct: 7450 ENFLTSIHILNVDAADIGEYQCKATNDVGSDT 7481
Score = 75.9 bits (185), Expect = 5e-14
Identities = 61/222 (27%), Positives = 96/222 (43%), Gaps = 18/222 (8%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
++ I V G G YTC + +L+V PA+IV + V V E + L C+
Sbjct: 5104 TLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECV 5163
Query: 156 AVGRPEPTVTWRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
G PE V W L+DG F + I + + +G+Y N S
Sbjct: 5164 VAGTPELKVKW--LKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 5221
Query: 204 AP-DSRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ D+ ++ N PP+ T +T LG + + C+ P QW+KD + +S+ +
Sbjct: 5222 SSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST-S 5280
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
A+ V ER+ S L N+ NYTC+ +N G + S
Sbjct: 5281 AKYRLVCHERSVS-LEVNNLELEDTANYTCKVSNVAGDDACS 5321
Score = 74.7 bits (182), Expect = 1e-13
Identities = 67/283 (23%), Positives = 110/283 (38%), Gaps = 28/283 (9%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLINTPE 93
F D V G N T + + V+W S+ L G+ R ++ +
Sbjct: 7777 FVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGD---------RCNVSLED 7827
Query: 94 EFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNL 152
+ L + +V G YTC + +L + PA+ V + ++ +G + L
Sbjct: 7828 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLIL 7887
Query: 153 LCLAVGRPEPTVTWRQLRDGF------------TSEGEILEISDIQRGQAGEYECVTHNG 200
G P +VTW+ ++G T + ILEI AG+Y C N
Sbjct: 7888 EGTFTGTPPISVTWK--KNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENA 7945
Query: 201 VNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSG 260
S ++L+ + P + + + ++G +A L+C+ P WYK D L
Sbjct: 7946 SGKDSCSAQILI-LEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPT 8004
Query: 261 TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
T K+ + L+F V G Y C+A N +G SAS
Sbjct: 8005 TT--YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSAS 8045
Score = 70.9 bits (172), Expect = 2e-12
Identities = 59/214 (27%), Positives = 89/214 (41%), Gaps = 19/214 (8%)
Query: 102 VGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
+ + G YTC + L V PA + S +V G ++ L G
Sbjct: 5955 IDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLP 6014
Query: 162 PTVTWRQLRDGF------------TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
+VTW+ +DGF T + ILEI + + AG+Y C N + D
Sbjct: 6015 ISVTWK--KDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN--EAGRDVCG 6070
Query: 210 VLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
LV+ PP +T++ A+G + L+C+ P WYK D L T E
Sbjct: 6071 ALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRP-TPEYRTYF 6129
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
T + L+F V+ G YTC+A N +G +S+
Sbjct: 6130 TNNV-ATLVFNKVNINDSGEYTCKAENSIGTASS 6162
Score = 70.1 bits (170), Expect = 3e-12
Identities = 83/340 (24%), Positives = 132/340 (38%), Gaps = 47/340 (13%)
Query: 20 GLAVISRGLLSQSLEF----NSPADNYT-----VCEGDNATLSCFIDEHVTRVAWLNRSN 70
G I++ L SLE S + YT V G + + F+ E T V L S
Sbjct: 4250 GSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQ 4309
Query: 71 ILYAGND-----RWTSDPRVRLL---------------INTPEEFSIL-ITEVGLGDEGL 109
+L G+ + T P +++ ++ E ++L +T+VG+ D G
Sbjct: 4310 LLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGE 4369
Query: 110 YTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQ- 168
Y C Q +IV P+ V + +V LL G P +TW +
Sbjct: 4370 YMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKD 4429
Query: 169 ---LRDGFTSEGEI------LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPT 219
LR G + I L+I AGEY+C N V S+ S RV T+ PP+
Sbjct: 4430 NTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARV--TLREPPS 4487
Query: 220 -ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLF 278
I + S + G A + P W KD ++ + +++ E + L
Sbjct: 4488 FIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITED--DNIRMTFENNVASLYL 4545
Query: 279 ANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLENSA 316
+ + +H G Y C+A N G SA + + P ++ A
Sbjct: 4546 SGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEA 4585
Score = 69.7 bits (169), Expect = 3e-12
Identities = 56/213 (26%), Positives = 85/213 (39%), Gaps = 15/213 (7%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
+ G Y C + + + L V P + PV V + +V L C G P VT
Sbjct: 4928 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVT 4987
Query: 166 W----RQLRDG--FTSEGEI----LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
W R++R +T + L I+ GEY+C+ N S S R V +
Sbjct: 4988 WLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTR--VALK 5045
Query: 216 YPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
PP+ I + + T L +A + PP W KDD++L + + + + +
Sbjct: 5046 EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDED--DNVYISFVDSVA 5103
Query: 275 MLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
L +V H G YTC+A N G LL
Sbjct: 5104 TLQIRSVDNGHSGRYTCQAKNESGVERCYAFLL 5136
Score = 69.7 bits (169), Expect = 3e-12
Identities = 50/210 (23%), Positives = 87/210 (41%), Gaps = 24/210 (11%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVN-ISSPVTVNEGGNVNLLCLAVGRPEPTVTW 166
G YTC + L+V P + V + + V G + L C G PE V W
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457
Query: 167 ----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV-- 214
+ R F +++++++ +G++ C N S S +V+V
Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 5517
Query: 215 ---NYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER 271
++PP + + +A +L CE PP + WYKD R L S ++ K+ ++
Sbjct: 5518 VFSSFPPIVETLKNAEVSL------ECELSGTPPFEVVWYKDKRQLRS--SKKYKIASKN 5569
Query: 272 TRSMLLFANVSARHYGNYTCRAANRLGASS 301
+ + NV G Y C+A N +G+ +
Sbjct: 5570 FHTSIHILNVDTSDIGEYHCKAQNEVGSDT 5599
Score = 69.7 bits (169), Expect = 3e-12
Identities = 60/241 (24%), Positives = 97/241 (40%), Gaps = 21/241 (8%)
Query: 83 PRVRLLINTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP 141
P R I T E+ +IL I + D G Y C + + +++ P V P
Sbjct: 7910 PSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEP 7969
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQ----------LRDGFTSEGEILEISDIQRGQAG 191
V V+ G + +L C G PE V+W + + F + L + + +G
Sbjct: 7970 VKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSG 8029
Query: 192 EYECVTHNGVNSAPDSRRVLV-TVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQ 249
EY C N V S + V PP+ + + + +G + C P
Sbjct: 8030 EYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVS 8089
Query: 250 WYKDDRLLSSGTAEGLKVQT---ERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
WYKD + L + VQT + T ++ +F G Y+C A N +G++S+S RL
Sbjct: 8090 WYKDGKPLK----DSPNVQTSFLDNTATLNIF-KTDRSLAGQYSCTATNPIGSASSSARL 8144
Query: 307 L 307
+
Sbjct: 8145 I 8145
Score = 69.3 bits (168), Expect = 5e-12
Identities = 53/213 (24%), Positives = 78/213 (36%), Gaps = 14/213 (6%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G Y+C + + P V P+ G +V+L C G PE TV+
Sbjct: 6052 DAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 6111
Query: 166 WR----------QLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
W + R FT+ L + + +GEY C N + +A +
Sbjct: 6112 WYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQER 6171
Query: 216 Y-PPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP+ + +G L C P WY+D LL E L+
Sbjct: 6172 QLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDD--ENLQTSFVDNV 6229
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L H G Y+C A+N LG +S+S RL
Sbjct: 6230 ATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Score = 67.8 bits (164), Expect = 1e-11
Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 16/207 (7%)
Query: 104 LGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP-VTVNEGGNVNLLCLAVGRPEP 162
L D G Y C+ + + V P V P + G + L C G P
Sbjct: 3708 LKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVI 3767
Query: 163 TVTW----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLV 212
VTW +R F + IL+I+D++ +G Y C N V S DS +
Sbjct: 3768 QVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS--DSCSTEI 3825
Query: 213 TVNYPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER 271
+ PP+ I + A G ALL+CE P + W+KD + + S ++ ++ +++
Sbjct: 3826 VIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS--SKKYRLFSQK 3883
Query: 272 TRSMLLFANVSARHYGNYTCRAANRLG 298
+ L + ++ G Y C AN +G
Sbjct: 3884 SLVCLEIFSFNSADVGEYECVVANEVG 3910
Score = 67.0 bits (162), Expect = 2e-11
Identities = 70/286 (24%), Positives = 115/286 (40%), Gaps = 26/286 (9%)
Query: 29 LSQSLEFNSPADNYTVCEGDNATLSCFID-EHVTRVAWLNRSNILYAGNDRWTSDPRVRL 87
L + F S ++ TV G+ A L I+ V WL + R + + R+
Sbjct: 5606 LKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI----RESENIRITF 5661
Query: 88 LINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEG 147
+ N ++ + + G Y C + L+V PA IV + P+TV G
Sbjct: 5662 VENVA---TLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVG 5718
Query: 148 GNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRGQAGEYECVT 197
L C G PE +V W ++ + F ++ L I ++R AG Y
Sbjct: 5719 ETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQV 5778
Query: 198 HNGVNSAPDSRRVLVTVN-YPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDR 255
N V + + V V+ PP+ T + + LG + +L C+ P W+ +
Sbjct: 5779 QNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKT 5838
Query: 256 LLSSGTAEGLKVQTERTRSM--LLFANVSARHYGNYTCRAANRLGA 299
+ SG K QT + ++ L ++ + GNYTC AAN G+
Sbjct: 5839 KIVSGA----KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGS 5880
Score = 65.9 bits (159), Expect = 5e-11
Identities = 55/226 (24%), Positives = 83/226 (36%), Gaps = 17/226 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVH---VPARIVNISSPVTVNEGGNVNL 152
+++ +V + D G Y C + + +L V +P V G V
Sbjct: 8017 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVF 8076
Query: 153 LCLAVGRPEPTVTW----RQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVN 202
C G +V+W + L+D F L I R AG+Y C N +
Sbjct: 8077 DCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIG 8136
Query: 203 SAPDSRRVLVTVNYPPTITDVTSA--RTALGRAALLRCEAMAVPPADFQWYKDDRLLSSG 260
SA S R+++T P D+ A +G +A C P W KD R + SG
Sbjct: 8137 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 8196
Query: 261 TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++ + L V G YTC A N +G S + +L
Sbjct: 8197 GK--YQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 8240
Score = 63.5 bits (153), Expect = 2e-10
Identities = 61/258 (23%), Positives = 96/258 (37%), Gaps = 26/258 (10%)
Query: 63 VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYT 122
V WL S D T D +R+ S+ ++ + + +G Y C +
Sbjct: 4517 VTWLKDS-------DEITEDDNIRMTFEN-NVASLYLSGIEVKHDGKYVCQAKNDAGIQR 4568
Query: 123 TQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG---------- 172
L V PA I + + V +G L G E T W +DG
Sbjct: 4569 CSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKW--FKDGQELTLGSKYK 4626
Query: 173 --FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV-LVTVNYPPTITDVTSARTA 229
T IL+I ++ +GEY N V + R+ ++ + PP+ T +
Sbjct: 4627 ISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDS 4686
Query: 230 L-GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGN 288
+ G L C P QW+KDD+ +S+ +E K + L + + G
Sbjct: 4687 IKGSFIDLECIVAGSHPISIQWFKDDQEISA--SEKYKFSFHDNTAFLEISQLEGTDSGT 4744
Query: 289 YTCRAANRLGASSASMRL 306
YTC A N+ G + S L
Sbjct: 4745 YTCSATNKAGHNQCSGHL 4762
Score = 63.5 bits (153), Expect = 2e-10
Identities = 57/244 (23%), Positives = 84/244 (34%), Gaps = 15/244 (6%)
Query: 77 DRWTSDPRVRLLINTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI 135
D + R I E+ +IL I E + D Y+C + + + V P
Sbjct: 6963 DEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYF 7022
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTW----RQLRDG------FTSEGEILEISDI 185
+ V G L C G PE ++W +LR F + L I+ +
Sbjct: 7023 IEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKV 7082
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI--TDVTSARTALGRAALLRCEAMAV 243
GEY C N V + S +++ P + LG C
Sbjct: 7083 DHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGS 7142
Query: 244 PPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
P WYKD LL L+ + L H G Y C A+N LG +S+S
Sbjct: 7143 EPLQVSWYKDGVLLKDDA--NLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSS 7200
Query: 304 MRLL 307
+L+
Sbjct: 7201 AKLI 7204
Score = 63.2 bits (152), Expect = 3e-10
Identities = 65/301 (21%), Positives = 108/301 (35%), Gaps = 40/301 (13%)
Query: 37 SPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS 96
+P + EG A C + +V+W ++ D+ R + + +
Sbjct: 3349 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSK--------DKKIKPSRFFRMTQFEDTYQ 3400
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS----------------- 139
+ I E DEG YT ++ L + P I++
Sbjct: 3401 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKR 3460
Query: 140 --SPVTVNEGGNVNLLCLAVGRPEPTVTWRQL-RDGFTSEG---------EILEISDIQR 187
P+ V G C P W + R+ + S+ LEI Q
Sbjct: 3461 KIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQV 3520
Query: 188 GQAGEYECVTHNGVNSAPDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVPPA 246
GEY C N S + + VT YPPT ++ S T +G+AA C P
Sbjct: 3521 VDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI 3580
Query: 247 DFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ W KD LS + ++ + +L +N++ + G Y+C+A+N+ GA L
Sbjct: 3581 ETIWQKDGAALS--PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAEL 3638
Query: 307 L 307
+
Sbjct: 3639 I 3639
Score = 61.6 bits (148), Expect = 9e-10
Identities = 52/223 (23%), Positives = 89/223 (39%), Gaps = 20/223 (8%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
++ + + D G+Y+C + Q LI+ + PV V+L C
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDE 3669
Query: 159 RPEPTVTWRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
+ TVTW +DG F + LEI + +G Y C N S+
Sbjct: 3670 DRKVTVTWS--KDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSS-- 3725
Query: 207 SRRVLVTVNYPPTITDVTSARTAL--GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
S VTV PP+ + G +A L C+ P W+K+++ LS
Sbjct: 3726 SCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNT-- 3783
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
+++ + ++L +V G+Y+C A N +G+ S S ++
Sbjct: 3784 VRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIV 3826
Score = 58.5 bits (140), Expect = 8e-09
Identities = 57/228 (25%), Positives = 88/228 (38%), Gaps = 24/228 (10%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
+ G Y C + L V PARI+ P+TV G L C+ G PE +
Sbjct: 6618 NSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAK 6677
Query: 166 WRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVT 213
W +DG F ++ L+I + G Y N V + + V V+
Sbjct: 6678 W--FKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS 6735
Query: 214 --VNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTER 271
+ P I + LG + +L C P W++D + SG K Q+
Sbjct: 6736 DRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGP----KCQSSF 6791
Query: 272 TRSM--LLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLENS 315
+ ++ L + + G YTC AAN G+ SA + + P S E +
Sbjct: 6792 SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT 6839
Score = 58.2 bits (139), Expect = 1e-08
Identities = 59/293 (20%), Positives = 113/293 (38%), Gaps = 23/293 (7%)
Query: 28 LLSQSLEFNSPADNYTVCEGDNATLSCFI-DEHVTRVAWLNRSNILYAGNDRWTSDPRVR 86
LL + F D+ G TL + V W+ ++ D +++
Sbjct: 3919 LLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVI-------REDGKIK 3971
Query: 87 LLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNE 146
+ + ++I +V + G YTC + T+ LIV PA+I+ + + V
Sbjct: 3972 MSFSNGVAV-LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTA 4030
Query: 147 GGNVNLLCLAVGRPE----------PTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECV 196
G L G PE P V ++ R F + L+ + +G+Y
Sbjct: 4031 GDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFE 4090
Query: 197 THNGVNSAP-DSRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
N V S+ ++ ++ + P T + + + + L C+ P W+KD
Sbjct: 4091 ISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDG 4150
Query: 255 RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
+ +++ ++ ++ + L V GN+TCRA N +G+ +S L+
Sbjct: 4151 KEIAA--SDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALI 4201
Score = 58.2 bits (139), Expect = 1e-08
Identities = 57/259 (22%), Positives = 94/259 (36%), Gaps = 29/259 (11%)
Query: 63 VAWLNRSNILYAGNDRWTS--DPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP 120
V+W + N + +G T+ D L +N EE D G YTC
Sbjct: 7713 VSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEE----------SDSGDYTCIATNMAGS 7762
Query: 121 YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW----RQLRDGFTSE 176
L V P V P+ V G NV + G P +V+W +L G
Sbjct: 7763 DECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCN 7822
Query: 177 GEI------LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLV--TVNYPPTITDVTSART 228
+ LE+ D+ Q+GEY C+ N A + + + + + D + +
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEK- 7881
Query: 229 ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGN 288
G+ +L PP W K+ ++ ++ + T ++L + + G
Sbjct: 7882 --GKPLILEGTFTGTPPISVTWKKNG--INVTPSQRCNITTTEKSAILEIPSSTVEDAGQ 7937
Query: 289 YTCRAANRLGASSASMRLL 307
Y C N G S S ++L
Sbjct: 7938 YNCYIENASGKDSCSAQIL 7956
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/220 (24%), Positives = 83/220 (37%), Gaps = 16/220 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
SI I V D G Y C Q T + + P R V+ + +TV G L
Sbjct: 5573 SIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQAS 5632
Query: 156 AVGRPEPTVTWRQLRDGFTSEGEILEISDIQR-----------GQAGEYECVTHNGVNSA 204
G V W + ++ E E + I+ ++ AG+Y C N
Sbjct: 5633 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMR 5692
Query: 205 PDSRRVLVTVNYPPTITDVTSART-ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
+ ++V P I + T +G L C+ P +WYKD +LL+S ++
Sbjct: 5693 ENMATLMVL--EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS--SQ 5748
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
K S L +V + G YT + N +G SS +
Sbjct: 5749 KHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCT 5788
Score = 57.0 bits (136), Expect = 2e-08
Identities = 54/225 (24%), Positives = 83/225 (36%), Gaps = 18/225 (8%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
++ + V + G YTC + L V PA IV + V G L C
Sbjct: 7549 TLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECT 7608
Query: 156 AVGRPEPTVTWRQLRDGFTSEGEI----------LEISDIQRGQAGEYECVTHNGVNSAP 205
G PE + W + TS+ + L+I ++ +G Y N V
Sbjct: 7609 VAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDS 7668
Query: 206 DSRRVLVT-VNYPPTITDVTSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
+ + V+ PP+ T L G + ++ C+ PP W+ + +SSG
Sbjct: 7669 CTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGR-- 7726
Query: 264 GLKVQTERTRS--MLLFANVSARHYGNYTCRAANRLGASSASMRL 306
K QT T + L + G+YTC A N G+ S L
Sbjct: 7727 --KYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPL 7769
Score = 56.6 bits (135), Expect = 3e-08
Identities = 61/248 (24%), Positives = 88/248 (35%), Gaps = 25/248 (10%)
Query: 63 VAWLNRSNILYAGNDRWT--SDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP 120
VAW + + +G T SD L +N+ + D G YTC
Sbjct: 5831 VAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDS----------SDMGNYTCVAANVAGS 5880
Query: 121 YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW----RQLRDG---- 172
+ L V P V P+ V G NV + G P V W R+L G
Sbjct: 5881 DECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCN 5940
Query: 173 --FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTAL 230
F LE+ +I Q+GEY CV N A + R+ V + ++
Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVK-EPAAFLKRLSDHSVEP 5999
Query: 231 GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYT 290
G++ +L P W KD + T+E + T +L N + R G Y+
Sbjct: 6000 GKSIILESTYTGTLPISVTWKKDG--FNITTSEKCNIVTTEKTCILEILNSTKRDAGQYS 6057
Query: 291 CRAANRLG 298
C N G
Sbjct: 6058 CEIENEAG 6065
Score = 55.5 bits (132), Expect = 7e-08
Identities = 68/322 (21%), Positives = 107/322 (33%), Gaps = 39/322 (12%)
Query: 27 GLLSQSLE---FNSPADNYTVCEGDNATLSCFI--DEHVTRVAWLNRSNILYAGNDRWTS 81
G L +LE F + + GD+ +L C + +T V+W Y G+ +
Sbjct: 6070 GALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEIT-VSW-------YKGDTKLRP 6121
Query: 82 DPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIV---HVPARIVNI 138
P R T +++ +V + D G YTC + +++ + +P
Sbjct: 6122 TPEYRTYF-TNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 6180
Query: 139 SSPVTVNEGGNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRG 188
+ G V L C G V W L+ F L+I
Sbjct: 6181 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLS 6240
Query: 189 QAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDV--TSARTALGRAALLRCEAMAVPPA 246
+G+Y C N + +A S R+ D+ S G +A C P
Sbjct: 6241 HSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPM 6300
Query: 247 DFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
W KD++ + G + L V G YTC+A N +G S +L
Sbjct: 6301 RITWSKDNKEIRPG--GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Query: 307 LRPGSLENSAPRPPGLLALLSA 328
S PP + L A
Sbjct: 6359 --------SVKEPPKFVKKLEA 6372
Score = 55.1 bits (131), Expect = 9e-08
Identities = 56/227 (24%), Positives = 83/227 (36%), Gaps = 22/227 (9%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVN---- 151
S+ I V D G YT FQ ++ + +V V R V S + G V
Sbjct: 5760 SLRILSVERQDAGTYT--FQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASC 5817
Query: 152 -LLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNG 200
L C G +V W + + F+ L+++ + G Y CV N
Sbjct: 5818 ILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANV 5877
Query: 201 VNSAPDSRRVLVTVNYPPTITDVTSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSS 259
S D R ++TV PP+ L G+ PP W++ R L
Sbjct: 5878 AGS--DECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVK 5935
Query: 260 GTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
G + + E T + L N+ G YTC +N G +S + RL
Sbjct: 5936 G--DRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL 5980
Score = 55.1 bits (131), Expect = 9e-08
Identities = 59/229 (25%), Positives = 85/229 (37%), Gaps = 16/229 (6%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ I E D G Y C + L V P SPV +G +V L C
Sbjct: 6422 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEI 6481
Query: 157 VGRPEPTVTW----RQLRDG----FTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPD 206
G P V W +Q+R+ TS+ L I +++ GEY C N V S D
Sbjct: 6482 SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGS--D 6539
Query: 207 SRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+ V PP + ++ T +G A LR P W K DR +E
Sbjct: 6540 TCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK-DRGEVIRESENT 6598
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSL 312
++ + L + A + G Y C+ N G SA + +L P +
Sbjct: 6599 RISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARI 6647
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/256 (23%), Positives = 95/256 (37%), Gaps = 46/256 (17%)
Query: 93 EEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVP--------------ARIVNI 138
+E+++L+ E D +YTC + + TT L V VP A I +
Sbjct: 3292 QEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPL 3351
Query: 139 SSPVTVNEGGNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRG 188
VT +EG C G + V+W R R + LEI++
Sbjct: 3352 QDTVT-SEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3409
Query: 189 QAGEYECVTHNGVNS----------APDS-------RRVLVTVNYPPTIT-DVTSARTAL 230
G Y V N V AP+S + + + + P I + AL
Sbjct: 3410 DEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVAL 3469
Query: 231 GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYT 290
G A CE + P FQW+K R + ++ +++ + S L G YT
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGREIYE--SDKCSIRSSKYISSLEILRTQVVDCGEYT 3527
Query: 291 CRAANRLGASSASMRL 306
C+A+N G+ S + L
Sbjct: 3528 CKASNEYGSVSCTATL 3543
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/285 (24%), Positives = 107/285 (37%), Gaps = 27/285 (9%)
Query: 47 GDNATLSCFI-DEHVTRVAWLNRSNILYAGND-RWTSDPRVRLLINTPEEFSILITEVGL 104
GD++ L C I RV W + L A + R T V ++ + + L TE
Sbjct: 5438 GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI-----QMNNLSTE--- 5489
Query: 105 GDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTV 164
D G + C Q + +IV P + V + V+L C G P V
Sbjct: 5490 -DSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEV 5548
Query: 165 TW----RQLRDG----FTSEG--EILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV 214
W RQLR S+ + I ++ GEY C N V S D+ V +
Sbjct: 5549 VWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS--DTCVCTVKL 5606
Query: 215 NYPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP ++ + S G A L+ P QW K+ + +E +++
Sbjct: 5607 KEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIR-ESENIRITFVENV 5665
Query: 274 SMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSA 316
+ L FA + G Y C+ N G + A++ +L P + A
Sbjct: 5666 ATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKA 5710
Score = 53.1 bits (126), Expect = 3e-07
Identities = 51/213 (23%), Positives = 74/213 (34%), Gaps = 16/213 (7%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G YTCS + +L V P V VN V L L G T+
Sbjct: 4741 DSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIK 4800
Query: 166 W----RQLRDGFT------SEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
W ++L G LE+ + +G Y C N V +A + + + V
Sbjct: 4801 WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTA--TSKATLFVK 4858
Query: 216 YPPTITDVTSARTAL--GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP S L G++ C+ P WY D +++ G+
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 4918
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ A V + G Y C A N G +S S+ L
Sbjct: 4919 FQISGARV--ENSGTYVCEARNDAGTASCSIEL 4949
Score = 52.8 bits (125), Expect = 4e-07
Identities = 55/244 (22%), Positives = 92/244 (37%), Gaps = 20/244 (8%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-SPVTVN--EGGNVNL 152
++ I + L G Y+CS ++ L P + PV+++ G + +
Sbjct: 6231 TLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADF 6290
Query: 153 LCLAVGRPEPTVTW----RQLRDG----FTSEGEI--LEISDIQRGQAGEYECVTHNGVN 202
C G +TW +++R G T G L I + +G +G+Y C N V
Sbjct: 6291 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 6350
Query: 203 SAPDSRRVLVTVNYPPTITDVTSARTAL--GRAALLRCEAMAVPPADFQWYKDDRLLSSG 260
D ++V PP A G + L C+ P W+++D L
Sbjct: 6351 K--DMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 6408
Query: 261 TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL-LRPGSLENSAPRP 319
+ + ++L SA G+Y C A N +G +S S L ++ + P P
Sbjct: 6409 WKYNMSFIN--SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSP 6466
Query: 320 PGLL 323
G L
Sbjct: 6467 VGAL 6470
Score = 52.0 bits (123), Expect = 7e-07
Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 15/147 (10%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS---SPVTVNEGGNVNLLCL 155
+ + G+ D GLYTC +++ P + +PVTV+EG V L C
Sbjct: 8309 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCH 8368
Query: 156 AVGRPEPTVTW----RQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAP 205
G + W R+++ F S +LE+ D+ + +G+Y C N S
Sbjct: 8369 VQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGS-- 8426
Query: 206 DSRRVLVTVNYPPTITDVTSARTALGR 232
D+ + VT+ P + T GR
Sbjct: 8427 DTTKSKVTIKDKPAVAPATKKAAVDGR 8453
Score = 52.0 bits (123), Expect = 7e-07
Identities = 73/280 (26%), Positives = 107/280 (38%), Gaps = 49/280 (17%)
Query: 33 LEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWL-NRSNILYAGNDRWTSDPRVRLLI-- 89
+EF P ++ TV EG A L C + +V W N + IL + +D RVR L+
Sbjct: 12285 VEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIH 12344
Query: 90 -NTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVT---VN 145
TPE+ YTC + + T L V P V P+T V
Sbjct: 12345 DCTPEDIK------------TYTCD----AKDFKTSCNLNVVPPH--VEFLRPLTDLQVR 12386
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEG--EILEISDIQRGQAGEY 193
E C + R V W +DG S+G IL I+ EY
Sbjct: 12387 EKEMARFEC-ELSRENAKVKW--FKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 12443
Query: 194 ECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYK- 252
C V +A S + V ++ + + L CE ++ P A+ WYK
Sbjct: 12444 SC----EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCE-VSKPGAEVIWYKG 12498
Query: 253 DDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCR 292
D+ ++ +G E + TE + +L+ N GNY CR
Sbjct: 12499 DEEIIETGRYE---ILTEGRKRILVIQNAHLEDAGNYNCR 12535
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/281 (20%), Positives = 104/281 (37%), Gaps = 35/281 (12%)
Query: 47 GDNATLSCFIDEHVT-----RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITE 101
G++A C HVT +V+W S + +G ++ L N+ + + +
Sbjct: 8167 GESADFEC----HVTGTQPIKVSWAKDSREIRSGGKY-----QISYLENSAH---LTVLK 8214
Query: 102 VGLGDEGLYTCSF--QTRHQPYTTQVYLIVHV--PARIVNISSPVTVNEGGNVNLLCLAV 157
V GD G YTC + T Q+ + + P+ +S V EG + L
Sbjct: 8215 VDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVA 8274
Query: 158 GRPEPTVTWRQ----------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
G TV W + F + +L++ AG Y C N SA +
Sbjct: 8275 GSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCT 8334
Query: 208 RRVLVTVNYPPTITD--VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+++ P + D +T + G L C P QW K R + ++
Sbjct: 8335 SSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKP--SDRC 8392
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++L +V+ G+Y C+A+N G+ + ++
Sbjct: 8393 SFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKV 8433
Score = 49.7 bits (117), Expect = 4e-06
Identities = 46/204 (22%), Positives = 73/204 (35%), Gaps = 15/204 (7%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G+YTC L V P V V G ++ + G P V
Sbjct: 6807 DTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVK 6866
Query: 166 W----RQLRDGFTSEGEI------LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
W R+L G + + LE+ ++Q ++G+Y C+ N SA + + V
Sbjct: 6867 WFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF--VK 6924
Query: 216 YPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
P T + + G +L PP W KD+ L+S +E + +
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQ--SERCSITMTEKST 6982
Query: 275 MLLFANVSARHYGNYTCRAANRLG 298
+L + Y Y+C N G
Sbjct: 6983 ILEILESTIEDYAQYSCLIENEAG 7006
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 13/169 (7%)
Query: 148 GNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRGQAGEYECVT 197
G L C G V+W + R F LEI + AG + C
Sbjct: 4128 GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 4187
Query: 198 HNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
N V S DS L+ P +T S G A L+ P +W+K ++ L
Sbjct: 4188 TNSVGS-KDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL 4246
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
SG + + E S L V G YTC+ +N G S L
Sbjct: 4247 VSGGS--CYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL 4293
Score = 49.3 bits (116), Expect = 5e-06
Identities = 49/226 (21%), Positives = 86/226 (38%), Gaps = 18/226 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIV---HVPARIVNISSPVTVNEGGNVNL 152
S I V D G YT + + YL V ++P + + G ++++
Sbjct: 5197 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHM 5256
Query: 153 LCLAVGRPEPTVTWRQLRDGFTSEGEI----------LEISDIQRGQAGEYECVTHNGVN 202
C G + W + ++ + LE+++++ Y C N
Sbjct: 5257 ECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG 5316
Query: 203 SAPDSRRVLVTVNYPPTITDVTSARTALGRAAL-LRCEAMAVPPADFQWYKDDRLLSSGT 261
D+ ++TV PP+ + A+ + + + PP +W+KDD L SG
Sbjct: 5317 D--DACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGP 5374
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
+ E + S L +V A G YTC N +G+ S + LL
Sbjct: 5375 K--CFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLL 5418
Score = 48.9 bits (115), Expect = 6e-06
Identities = 57/255 (22%), Positives = 96/255 (37%), Gaps = 33/255 (12%)
Query: 28 LLSQSLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGND-RWTSDPRVR 86
++ EF ++ TV E D+A SC + V W + G ++ D +
Sbjct: 12818 IIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIH 12877
Query: 87 LLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNE 146
LI I + L DE Y C + R + + +P I+ +
Sbjct: 12878 RLI---------IKDCRLDDECEYACGVEDRK---SRARLFVEEIPVEIIRPPQDILEAP 12925
Query: 147 GGNVNLLCLAVGRPEPTVTWRQLRDGFT----------SEGEI--LEISDIQRGQAGEYE 194
G +V L + + + V W LR+ SEG+I L+I DI+ GEY
Sbjct: 12926 GADVVFLA-ELNKDKVEVQW--LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYR 12982
Query: 195 CVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
+ + ++R L P T +G+ + A P A+ +W+K++
Sbjct: 12983 FIAKD-----KEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKEN 13037
Query: 255 RLLSSGTAEGLKVQT 269
LS+ T + QT
Sbjct: 13038 EPLSTKTIDTTAEQT 13052
Score = 48.5 bits (114), Expect = 8e-06
Identities = 56/240 (23%), Positives = 89/240 (37%), Gaps = 29/240 (12%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ I+E D G YT F + +Y+ P +++ PVTV G +
Sbjct: 3205 MFISETRQSDAGEYT--FVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVI 3262
Query: 157 VGRPEPTVTW----RQLRDGF------TSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
GRP+P ++W + L GF + L + + A Y C N A
Sbjct: 3263 SGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATT 3322
Query: 207 SRRVLVTVN-----------YPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
S + V V YPP IT + T+ G+ A +C WY D
Sbjct: 3323 SASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKD 3381
Query: 255 RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSL 312
+ + + ++ L A G YT A+N +G +S+A++ L P S+
Sbjct: 3382 KKIK--PSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3439
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/181 (23%), Positives = 73/181 (40%), Gaps = 18/181 (9%)
Query: 138 ISSPVTVNEGGNVNLLCLAVGRPEPTVTW----RQLRDGFTSEGEILE------ISDIQR 187
+S + + E G C G +TW R++R G + ++E + + +
Sbjct: 7219 VSVDLALGESGTFK--CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGK 7276
Query: 188 GQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLR--CEAMAVPP 245
G AG+Y C N + DS + V PP + + R C+ P
Sbjct: 7277 GDAGQYTCYASN--IAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPE 7334
Query: 246 ADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMR 305
WYKD+ + + ++ + ++L N+S G+YTC A N G++S+S
Sbjct: 7335 IKVLWYKDETEIQESSK--FRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTS 7392
Query: 306 L 306
L
Sbjct: 7393 L 7393
Score = 45.4 bits (106), Expect = 7e-05
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 12/124 (9%)
Query: 192 EYECVTHNGVNSAPDSRR----VLVTVNYPPTITDVTSARTAL-----GRAALLRCEAMA 242
++ + VN +P S ++ N PP I D++ A +L G L
Sbjct: 19263 QFRAIARTAVNISPPSEPSDPVTILAENVPPRI-DLSVAMKSLLTVKAGTNVCLDATVFG 19321
Query: 243 VPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
P W KD LL AEG+K+ +R L +V+ + G+YT A N G+ SA
Sbjct: 19322 KPMPTVSWKKDGTLLKP--AEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSA 19379
Query: 303 SMRL 306
+++L
Sbjct: 19380 TIKL 19383
Score = 45.4 bits (106), Expect = 7e-05
Identities = 42/201 (20%), Positives = 76/201 (37%), Gaps = 19/201 (9%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDIQRGQAG 191
VT G L C VGRP P + W R+ + L + ++ G
Sbjct: 30542 VTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEG 30601
Query: 192 EYECVTHNGVNSAPDSRRVLV--TVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQ 249
Y C+ N V S ++L+ T + P A+G L + P
Sbjct: 30602 VYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMT 30661
Query: 250 WYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSAR-HYGNYTCRAANRLGASSASMRLLR 308
W+ +LL + +E + ++ + L+ NV + H G Y + +N G A + +
Sbjct: 30662 WFHGQKLLQN--SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDV-- 30717
Query: 309 PGSLENSAPRPPGLLALLSAL 329
+++ +P G + + + L
Sbjct: 30718 --EIQDKPDKPTGPIVIEALL 30736
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Query: 172 GFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTAL- 230
G L + + + G+Y C N V S DS ++ V PP A +
Sbjct: 5379 GLEGSTSFLNLYSVDASKTGQYTCHVTNDVGS--DSCTTMLLVTEPPKFVKKLEASKIVK 5436
Query: 231 -GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNY 289
G ++ L C+ P W++++ L + ++ ++ + +++ N+S G++
Sbjct: 5437 AGDSSRLECKIAGSPEIRVVWFRNEHELPA--SDKYRMTFIDSVAVIQMNNLSTEDSGDF 5494
Query: 290 TCRAANRLGASSASMRLL 307
C A N G++S S +++
Sbjct: 5495 ICEAQNPAGSTSCSTKVI 5512
Score = 43.9 bits (102), Expect = 2e-04
Identities = 45/199 (22%), Positives = 73/199 (36%), Gaps = 17/199 (8%)
Query: 122 TTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW----------RQLRD 171
T+Q V A I S+ +++NEG + L G + V W + R
Sbjct: 33028 TSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATD--VKWVLNGVELTNSEEYRY 33085
Query: 172 GFTSEGEILEISDIQRGQAGEYECV--THNGVNSAPDSRRVLVTVNYPPT-ITDVTSART 228
G + + L I G C+ T G+ + ++ P I+ S
Sbjct: 33086 GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNI 33145
Query: 229 ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGN 288
G+ L CE P + +W+K++ L + + + R L N S G
Sbjct: 33146 NEGQNVLFTCEISGEPSPEIEWFKNN--LPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203
Query: 289 YTCRAANRLGASSASMRLL 307
YT +A N G SA+ L+
Sbjct: 33204 YTIKAKNFRGQCSATASLM 33222
Score = 43.1 bits (100), Expect = 3e-04
Identities = 52/220 (23%), Positives = 82/220 (37%), Gaps = 26/220 (11%)
Query: 47 GDNATLSCFIDEHVTRVAWL-NRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLG 105
G +A C + W+ + SNI + R+ +D + R L I +V L
Sbjct: 11133 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLH---------IIDVQLS 11183
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIV-HVPARIV-NISSPVTVNEGGNVNLLCLAVGRPEPT 163
D G YTC + ++ T+ L+V +P R V + VTV +G + L C E
Sbjct: 11184 DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERD 11241
Query: 164 VTWR-----------QLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLV 212
V WR ++ G L I+D AG Y N N S +V
Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301
Query: 213 TVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYK 252
V + + A+ C+ +A + +W+K
Sbjct: 11302 EVIRDWLVKPIRDQHVKPKGTAIFACD-IAKDTPNIKWFK 11340
Score = 42.4 bits (98), Expect = 6e-04
Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 2/140 (1%)
Query: 168 QLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR 227
+++D + G +LE ++ + E E +A + L + P ++
Sbjct: 30484 RIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 30543
Query: 228 TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYG 287
T LG AA L C+ + P D +WY+ + L + K+ ++ L G
Sbjct: 30544 TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ--SRKYKMSSDGRTHTLTVMTEEQEDEG 30601
Query: 288 NYTCRAANRLGASSASMRLL 307
YTC A N +G S +LL
Sbjct: 30602 VYTCIATNEVGEVETSSKLL 30621
Score = 42.4 bits (98), Expect = 6e-04
Identities = 46/190 (24%), Positives = 68/190 (35%), Gaps = 32/190 (16%)
Query: 143 TVNEGGNVNLLCLAVGRPEPTVTW----RQLRDG-----FTSEGEI----LEISDIQRGQ 189
T G NV PEP VTW ++++ G +T E + L I+ +
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759
Query: 190 AGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDV--------TSARTALGRAALLRCEAM 241
EY V N ++ VT++ PPT + + +A G++
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVS 31819
Query: 242 AVPPADFQWYKDDRLLSSG-----TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANR 296
+PP +W KD + LS G EGL R L G Y A N
Sbjct: 31820 GIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTL------PEDTGYYRVTATNT 31873
Query: 297 LGASSASMRL 306
G++S L
Sbjct: 31874 AGSTSCQAHL 31883
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 218 PTITDVTSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSML 276
PT T + L G A P + W++D +++S+ T G+++ R+ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 277 LFANVSARHYGNYTCRAANRLGASSASMRLL 307
V+ + G Y+ +A N G ++++ LL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELL 96
Score = 40.8 bits (94), Expect = 0.002
Identities = 63/288 (21%), Positives = 106/288 (36%), Gaps = 41/288 (14%)
Query: 33 LEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDR-WTSDPRVRLLINT 91
+EF P + V E + A C + +V W + G S VR+L+
Sbjct: 12374 VEFLRPLTDLQVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILV-- 12431
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVN 151
I + L DE Y+C +T T+ + ++ A + + V+E +
Sbjct: 12432 -------INKCLLDDEAEYSCEVRTAR---TSGMLTVLEEEAVFTKNLANIEVSETDTIK 12481
Query: 152 LLCLAVGRPEPTVTWRQLRDGFTSEGE----------ILEISDIQRGQAGEYECVTHNGV 201
L+C V +P V W + + G IL I + AG Y C
Sbjct: 12482 LVC-EVSKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC------ 12534
Query: 202 NSAPDSR---RVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS 258
P SR +V V I+ + G A C +++ QW +DD+ L
Sbjct: 12535 -RLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC-SISKESFPVQWKRDDKTLE 12592
Query: 259 SGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
SG + V + + +L+ + + + G Y +GA+ A+ L
Sbjct: 12593 SG--DKYDVIADGKKRVLVVKDATLQDMGTYVV----MVGAARAAAHL 12634
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/208 (21%), Positives = 80/208 (38%), Gaps = 27/208 (12%)
Query: 128 IVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQR 187
I + V++S +GG+ + R P W + +E + + IS + +
Sbjct: 26776 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFI-ISGLTQ 26834
Query: 188 GQAGEYECVTHNGVNSAPDSRRVL-----------VTVNYPPTITDVTSARTALGRAALL 236
E+ N V S + V+ ++ P T+V R G + L
Sbjct: 26835 NSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRA--GTSVKL 26892
Query: 237 RCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANR 296
R P +WYKDD+ L + + V+ + +L + + G Y + N
Sbjct: 26893 RAGISGKPAPTIEWYKDDKELQTNAL--VCVENTTDLASILIKDADRLNSGCYELKLRNA 26950
Query: 297 LGASSASMR---LLRPGSLENSAPRPPG 321
+G++SA++R L +PG PPG
Sbjct: 26951 MGSASATIRVQILDKPG--------PPG 26970
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 10/111 (9%)
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGF----------TSEGEILEISDI 185
V + + V G +V +L GRP PTVTWR+ T +L I +
Sbjct: 27275 VALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQV 27334
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALL 236
R G+Y NGV S + ++ P + + G LL
Sbjct: 27335 TRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 27385
Score = 38.9 bits (89), Expect = 0.007
Identities = 24/97 (24%), Positives = 37/97 (38%), Gaps = 2/97 (2%)
Query: 210 VLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQT 269
V + V P ++ + + G + L C P WY++D + S + Q+
Sbjct: 936 VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS 995
Query: 270 ERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
R L+ A G +TC A N G S S L
Sbjct: 996 GIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYL 1030
Score = 37.7 bits (86), Expect = 0.015
Identities = 51/239 (21%), Positives = 74/239 (30%), Gaps = 59/239 (24%)
Query: 132 PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI------------ 179
P +V+ VTV EG +V L C G P PTVTW R+ + E I
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTW--YREDYQIESSIDFQITFQSGIAR 999
Query: 180 LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN------------------------ 215
L I + +G + C N + S + V V+
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059
Query: 216 ---------------------YPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
P IT + G + + C+ P W K
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSG 1119
Query: 255 RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLE 313
L++G + + L+ + A G YT N+ G +SAS LL E
Sbjct: 1120 VPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 133 ARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG------------FTSEGEIL 180
ARI+ +TV EG + C G P PTVTW LR G T
Sbjct: 32561 ARILTKPRSMTVYEGESARFSCDTDGEPVPTVTW--LRKGQVLSTSARHQVTTTKYKSTF 32618
Query: 181 EISDIQRGQAGEYECVTHN 199
EIS +Q G Y V N
Sbjct: 32619 EISSVQASDEGNYSVVVEN 32637
Score = 37.4 bits (85), Expect = 0.019
Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 19/119 (15%)
Query: 119 QPYTTQVYLIVHVPARI---VNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGF-- 173
+P L +VP RI V + S +TV G NV L G+P PTV+W+ +DG
Sbjct: 19279 EPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWK--KDGTLL 19336
Query: 174 -TSEGE---------ILEISDIQRGQAGEYECVTHN--GVNSAPDSRRVLVTVNYPPTI 220
+EG LE+ + R +G+Y N G SA +VL P ++
Sbjct: 19337 KPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 19395
Score = 37.0 bits (84), Expect = 0.025
Identities = 67/291 (23%), Positives = 108/291 (37%), Gaps = 42/291 (14%)
Query: 33 LEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTP 92
L+F SP ++ TV EG+ AT C + V W ND R L+ +
Sbjct: 11574 LKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFK--------NDAKLHTSRTVLISSEG 11625
Query: 93 EEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNL 152
+ + + EV L D + Q + T Q+ ++ P V + V E + L
Sbjct: 11626 KTHKLEMKEVTLDD--ISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV-EKDEITL 11682
Query: 153 LCLAVGRPEPTVTWRQLRDG----------FTSEG--EILEISDIQRGQAGEYEC---VT 197
C V + P V W +DG ++G IL+I GEY C
Sbjct: 11683 KC-EVSKDVP-VKW--FKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTD 11738
Query: 198 HNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQW-YKDDRL 256
N ++R L+ V P + +G A E ++ P QW K L
Sbjct: 11739 KTKANVTVEAR--LIKVEKP-----LYGVEVFVGETAHFEIE-LSEPDVHGQWKLKGQPL 11790
Query: 257 LSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
+S E + + + +L+ N G + +AAN A++ ++ L
Sbjct: 11791 TASPDCE---IIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKEL 11838
Score = 37.0 bits (84), Expect = 0.025
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEP 162
G+G+ G T + + + + + L V RIV V+ GG + ++ G+P P
Sbjct: 16502 GIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIV-------VHAGGVIRIIAYVSGKPPP 16554
Query: 163 TVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEYECVTHN 199
TVTW E I + I + QR G Y + N
Sbjct: 16555 TVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKN 16599
Score = 37.0 bits (84), Expect = 0.025
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQ--------LRDGF--TSEGEILEISDIQRGQAG 191
V G N+ + +GRP+PTVTW++ R F T+ IL I++ R +G
Sbjct: 21075 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSG 21134
Query: 192 EYECVTHNGVNSAPDSRRVLV-TVNYPPT 219
Y N V D + V + PPT
Sbjct: 21135 PYPLTARNIVGEVGDVITIQVHDIPGPPT 21163
Score = 36.6 bits (83), Expect = 0.033
Identities = 48/185 (25%), Positives = 68/185 (36%), Gaps = 37/185 (20%)
Query: 43 TVCEGDNATLSCFID-EHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSIL-IT 100
TV EG+ LSC + R+ WL AG + SD R + ++L +
Sbjct: 8356 TVSEGEYVQLSCHVQGSEPIRIQWLK------AGREIKPSD---RCSFSFASGTAVLELR 8406
Query: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVH-------------VPARIVNISSP--VTVN 145
+V D G Y C TT+ + + V R+ +S P + V
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVV 8466
Query: 146 EGGNVNLLCLAVGRPEPTVTW-----RQLRDG----FTSEGEI--LEISDIQRGQAGEYE 194
E + G P P V W RQL G +G+ LEI D + +G Y
Sbjct: 8467 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYR 8526
Query: 195 CVTHN 199
CV N
Sbjct: 8527 CVAFN 8531
Score = 35.8 bits (81), Expect = 0.056
Identities = 46/174 (26%), Positives = 68/174 (39%), Gaps = 26/174 (14%)
Query: 68 RSNILYAGNDRW-------TSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQP 120
++NI A + +W T+ R ++ ++ ++ I + DEG+ TC +T+
Sbjct: 33059 KANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQ-TLTIKQASHRDEGILTCISKTKEGI 33117
Query: 121 YTTQVYLIVH-----VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW--RQLRDGF 173
Q L + PA I S +NEG NV C G P P + W L
Sbjct: 33118 VKCQYDLTLSKELSDAPAFISQPRSQ-NINEGQNVLFTCEISGEPSPEIEWFKNNLPISI 33176
Query: 174 TSEGEI--------LEISDIQRGQAGEYECVTHN--GVNSAPDSRRVLVTVNYP 217
+S I LEI + +G+Y N G SA S VL V P
Sbjct: 33177 SSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEP 33230
Score = 35.4 bits (80), Expect = 0.073
Identities = 38/182 (20%), Positives = 64/182 (35%), Gaps = 19/182 (10%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEILEISDIQRG------------Q 189
+ V N L+C G P+P V W + ++G I + + G
Sbjct: 30937 LNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDD 30996
Query: 190 AGEYECVTHNGVNSAPDSRRVLVTV----NYPPTITDVTSARTALGRAALLRCEAMAVPP 245
A Y+ N S + + V V + P T+ + + G ++ P
Sbjct: 30997 ATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPD 31056
Query: 246 ADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFAN-VSARHYGNYTCRAANRLGASSASM 304
W K L+ + +V R+ + L+F N V + G Y A NR G ++
Sbjct: 31057 PVITWQKGQDLIDNN--GHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 31114
Query: 305 RL 306
L
Sbjct: 31115 EL 31116
Score = 35.0 bits (79), Expect = 0.095
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 12/95 (12%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTW----RQLRDG----FTSEGEILEISDIQRGQAGEY 193
+ + GG++ L GRP P V W ++RD TS L + ++ R +G+Y
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKY 23011
Query: 194 ECVTHN--GVNSAPDSRRVLVTVNYPPT--ITDVT 224
N G SA + RVL T + P +T++T
Sbjct: 23012 TLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEIT 23046
Score = 35.0 bits (79), Expect = 0.095
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 12/106 (11%)
Query: 137 NISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRG 188
N V G ++ L GRP PT W + + +I L + + R
Sbjct: 28362 NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421
Query: 189 QAGEYECVTHN--GVNSAPDSRRVLVTVNYPPTIT--DVTSARTAL 230
AG+Y N G S + +VL T P IT DVT L
Sbjct: 28422 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATL 28467
Score = 35.0 bits (79), Expect = 0.095
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 12/91 (13%)
Query: 137 NISSPVTVNEGGNVNLLCLAVGRPEPTVTW---------RQLRDGFTSEGEILEISDIQR 187
++ VT+ G ++ L+ GRP P +TW R + D T +L + + R
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIID-TTESYSLLIVDKVNR 29509
Query: 188 GQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218
AG+Y N S S VLV V P
Sbjct: 29510 YDAGKYTIEAEN--QSGKKSATVLVKVYDTP 29538
Score = 34.3 bits (77), Expect = 0.16
Identities = 27/113 (23%), Positives = 47/113 (41%), Gaps = 9/113 (7%)
Query: 180 LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCE 239
L + + Q G Y V + SA + ++ + + DVT G+ + C+
Sbjct: 8714 LRVKNCQLKDQGNYRLVCGPHIASA---KLTVIEPAWERHLQDVTLKE---GQTCTMTCQ 8767
Query: 240 AMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCR 292
+VP +W+++ R+L K + E L A+V A G YTC+
Sbjct: 8768 -FSVPNVKSEWFRNGRILKPQGRH--KTEVEHKVHKLTIADVRAEDQGQYTCK 8817
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 13/98 (13%)
Query: 131 VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS----------EGEIL 180
+P +I+ + +T+ G + + G+P PT W++ D + IL
Sbjct: 18898 LPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 18956
Query: 181 EISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218
I D+ R +G Y N +S D++++ V V P
Sbjct: 18957 IIKDVTRKDSGYYSLTAEN--SSGTDTQKIKVVVMDAP 18992
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEY 193
+ V GG+ + GRP P +TW + FT + +I L I + R AG+Y
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 24093
Query: 194 ECVTHN--GVNSAPDSRRVLVTVNYPPTI 220
N G SA + +VL T P +
Sbjct: 24094 ILKLENSSGSKSAFVTVKVLDTPGPPQNL 24122
Score = 33.5 bits (75), Expect = 0.28
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 9/55 (16%)
Query: 128 IVHVPARIVNIS--SPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL 180
I+H P ++++ +TV G + +L GRPEP +TW T EG++L
Sbjct: 17902 ILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW-------TKEGKVL 17949
Score = 33.5 bits (75), Expect = 0.28
Identities = 36/154 (23%), Positives = 58/154 (37%), Gaps = 23/154 (14%)
Query: 75 GNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRH---QPYTTQVYLIVH- 130
G+D+W + V++ T IT + G+E + S Q P V +I
Sbjct: 22091 GSDKWATCATVKVTEAT-------ITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD 22143
Query: 131 --VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR----------QLRDGFTSEGE 178
+P + + TV G ++ + +GRP P VTW ++ T
Sbjct: 22144 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNS 22203
Query: 179 ILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLV 212
+L I D R G Y N A ++ V+V
Sbjct: 22204 LLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 33.1 bits (74), Expect = 0.36
Identities = 12/36 (33%), Positives = 21/36 (58%)
Query: 131 VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW 166
+P +I + S ++++EG + + C G P P VTW
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTW 33362
Score = 32.3 bits (72), Expect = 0.61
Identities = 41/156 (26%), Positives = 58/156 (37%), Gaps = 27/156 (17%)
Query: 120 PYTTQVYLIVHVPARIVNISSPVTVNE----GGNVNLLCLAVGRPEPTVTWRQLRDG--- 172
P+T Y + VP + V + + E G + CL V TW ++DG
Sbjct: 11105 PFT---YQLKAVPLKFVKEIKDIILTESEFVGSSAIFECL-VSPSTAITTW--MKDGSNI 11158
Query: 173 -------FTSEGEI--LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDV 223
F ++G+ L I D+Q AGEY CV G N S LV P
Sbjct: 11159 RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLG-NKEKTSTAKLVVEELPVRFVKT 11217
Query: 224 TSARTAL--GRAALLRCEAMAVPPADFQWYKDDRLL 257
+ G+ L CE D W KD +++
Sbjct: 11218 LEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIV 11251
Score = 32.3 bits (72), Expect = 0.61
Identities = 38/146 (26%), Positives = 56/146 (38%), Gaps = 12/146 (8%)
Query: 159 RPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYECVTHN--GVNSAPDSRRVLVT--- 213
R P W + E E +S + A E+ + N G S P +T
Sbjct: 21396 RDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD 21454
Query: 214 -VNYPPTITDVTSARTAL---GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQT 269
V P DV T + G A L + PP +W KD + L GTA+ L+++
Sbjct: 21455 DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAK-LEIKI 21512
Query: 270 ERTRSMLLFANVSARHYGNYTCRAAN 295
+ L+ + + R G YT A N
Sbjct: 21513 ADFSTNLVNKDSTRRDSGAYTLTATN 21538
Score = 31.6 bits (70), Expect = 1.0
Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 10/90 (11%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEY 193
V + + L GRPEP V W + T +I L I ++ R +G Y
Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 25176
Query: 194 ECVTHN--GVNSAPDSRRVLVTVNYPPTIT 221
N G +A + RVL + + P +T
Sbjct: 25177 NLTLENNSGSKTAFVNVRVLDSPSAPVNLT 25206
Score = 31.6 bits (70), Expect = 1.0
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 14/72 (19%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGF------------TSEGEILEISDIQRGQ 189
VTV G NV+L G+P+P+++W L+DG T L I + ++
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISW--LKDGLPLKESEFVRFSKTENKITLSIKNAKKEH 27630
Query: 190 AGEYECVTHNGV 201
G+Y + N V
Sbjct: 27631 GGKYTVILDNAV 27642
Score = 31.2 bits (69), Expect = 1.4
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 9/67 (13%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLR-DGFTSEGEI--------LEISDIQRGQAGE 192
V V G + L + GRP P VTWR++ D +G++ L I + R +G+
Sbjct: 18616 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGK 18675
Query: 193 YECVTHN 199
Y N
Sbjct: 18676 YSLTLVN 18682
Score = 30.8 bits (68), Expect = 1.8
Identities = 27/100 (27%), Positives = 38/100 (38%), Gaps = 9/100 (9%)
Query: 137 NISSPVTVNEGGNVNLLCLAVGRPEPTVTWR--------QLRDGFTSEGEILEISDIQRG 188
N++ + G + L + G P P VTW+ + R T G LEI +
Sbjct: 17223 NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHE 17282
Query: 189 QAGEYECVTHNGVNSAPDSRRVLVTVN-YPPTITDVTSAR 227
G Y N S S +VLV PP +V+ R
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIR 17322
Score = 30.4 bits (67), Expect = 2.3
Identities = 34/178 (19%), Positives = 65/178 (36%), Gaps = 19/178 (10%)
Query: 146 EGGNVNLLCLAVGRPEPTVTW----RQLRDGFTSEGEILE-------ISDIQRGQAGEYE 194
EG VGRP P W +Q+ + +T + I E I +GE+
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1529
Query: 195 CVTHNGVNSAPDSRRVLVTVNY------PPTITDVTSARTALGRAALLRCEAMAVPPADF 248
V N + S V++TV P + + + G ++ A P D
Sbjct: 1530 VVAQN--RAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587
Query: 249 QWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
W K+ ++ ++++ + + L + ++ YT A N+ G + ++
Sbjct: 1588 VWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1645
Score = 30.4 bits (67), Expect = 2.3
Identities = 19/93 (20%), Positives = 39/93 (41%), Gaps = 14/93 (15%)
Query: 143 TVNEGGNVNLLCLAVGRPEPTVTWRQLRDG------------FTSEGEILEISDIQRGQA 190
++ G ++ + +GRP P ++W ++DG T+ +L I + +
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISW--VKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDF 24379
Query: 191 GEYECVTHNGVNSAPDSRRVLVTVNYPPTITDV 223
G+Y N +A ++ V+V P + V
Sbjct: 24380 GKYTVTATNSAGTATENLSVIVLEKPGPPVGPV 24412
Score = 30.4 bits (67), Expect = 2.3
Identities = 23/105 (21%), Positives = 34/105 (32%), Gaps = 10/105 (9%)
Query: 135 IVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGE----------ILEISD 184
IV TV+ A G P PT W + T G+ LEI
Sbjct: 32854 IVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHK 32913
Query: 185 IQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTA 229
+G Y C N S S ++ + V++ +T+
Sbjct: 32914 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTS 32958
Score = 29.6 bits (65), Expect = 4.0
Identities = 21/81 (25%), Positives = 30/81 (37%), Gaps = 5/81 (6%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVH-----VPARIVNISSPVTVNEGGNV 150
S++I D G +T Q R + V L V V V V + EG +
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRL 1573
Query: 151 NLLCLAVGRPEPTVTWRQLRD 171
+ A G P P + W + D
Sbjct: 1574 EMKVRATGNPNPDIVWLKNSD 1594
Score = 29.6 bits (65), Expect = 4.0
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 14/104 (13%)
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTW----------RQLRDGFTSEGEILEISDI 185
V + + +TV G + L G+PEP +TW +++ + + I D
Sbjct: 13694 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS 13753
Query: 186 QRGQAGEY--ECVTHNGVNSAPDSRRVLVTVNYPPT--ITDVTS 225
+R G Y E V G +A VL P ITDVT+
Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTN 13797
Score = 29.6 bits (65), Expect = 4.0
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTW 166
+++ + V EG NVN++ G P PT+TW
Sbjct: 16120 IDLKEFMEVEEGTNVNIVAKIKGVPFPTLTW 16150
Score = 29.6 bits (65), Expect = 4.0
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 19/104 (18%)
Query: 144 VNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI-LEISDI-----------QRGQAG 191
+ G ++ + L GRP P VTW +DG E + +EI+D+ R G
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTW--FKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 192 EYECVTHNGVNSAPDSRRVLV-----TVNYPPTITDVTSARTAL 230
Y N SA +V V V P T++T + L
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTL 28071
Score = 29.3 bits (64), Expect = 5.2
Identities = 34/158 (21%), Positives = 65/158 (41%), Gaps = 24/158 (15%)
Query: 76 NDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLY---TCSFQTRHQPYTTQVYLIVH-- 130
+++W+ RV+ L +IT + G+E L+ + + R P + V ++
Sbjct: 23174 SEKWSECARVKSL-------QAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDL 23226
Query: 131 -VPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW--------RQLRDGFTSEGEI-- 179
+ + S +V G ++ + GRP+PT+TW + R T ++
Sbjct: 23227 VIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 23286
Query: 180 LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYP 217
L I + + G+Y N V S + VT++ P
Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTASIEI-VTLDKP 23323
Score = 28.9 bits (63), Expect = 6.8
Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 14/131 (10%)
Query: 182 ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN---YPPTITDVTSAR-----TALGRA 233
+ ++ Q E+ N + + S + V + PPTI S R G
Sbjct: 15356 VENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEP 15415
Query: 234 ALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERT-----RSMLLFANVSARHYGN 288
+ + +P +W K++ ++ T + L++ E ++ L G
Sbjct: 15416 VHIPADVTGLPMPKIEWSKNETVIEKPT-DALQITKEEVSRSEAKTELSIPKAVREDKGT 15474
Query: 289 YTCRAANRLGA 299
YT A+NRLG+
Sbjct: 15475 YTVTASNRLGS 15485
Score = 28.9 bits (63), Expect = 6.8
Identities = 16/64 (25%), Positives = 27/64 (42%), Gaps = 10/64 (15%)
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI----------LEISDIQRGQAGEYEC 195
E N L G+P P+V+W++ D ++ + L + D Q+ AG+Y
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20055
Query: 196 VTHN 199
N
Sbjct: 20056 TLKN 20059
Score = 28.5 bits (62), Expect = 8.9
Identities = 13/32 (40%), Positives = 14/32 (43%)
Query: 135 IVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW 166
IV PV V EG C G P+P V W
Sbjct: 1843 IVLYPEPVRVLEGETARFRCRVTGYPQPKVNW 1874
Score = 28.5 bits (62), Expect = 8.9
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 223 VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVS 282
V A T + A++R VP +W D + T E V+T+ S+L N
Sbjct: 17521 VVKAGTTVRFPAIIR----GVPVPTAKWTTDGSEIK--TDEHYTVETDNFSSVLTIKNCL 17574
Query: 283 ARHYGNYTCRAANRLGASSASMRL 306
R G Y +N G+ + ++ L
Sbjct: 17575 RRDTGEYQITVSNAAGSKTVAVHL 17598
Score = 28.5 bits (62), Expect = 8.9
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEY 193
+ V +GG + L G+P P W + + I L I + RG +G Y
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTY 30205
Query: 194 ECVTHN--GVNSAPDSRRVLVTVNYP 217
+ V N G + RV+ + N P
Sbjct: 30206 DLVLENKCGKKAVYIKVRVIGSPNSP 30231
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/237 (29%), Positives = 103/237 (43%), Gaps = 27/237 (11%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP---VTVNEGGNVNLL 153
+ + + L EG YTC + + L VHVP +I P V+V + G L
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 1088
Query: 154 CLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
C A G+P PTVTW RDG ++G+ L + Q G Y CV N
Sbjct: 1089 CNATGKPPPTVTWE--RDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1146
Query: 204 APDSRRVLVTVNYPPTITD----VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSS 259
A R+ ++V PP + +T+ AL L CEAM +PP +W++ + +S
Sbjct: 1147 A--ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSP 1204
Query: 260 GTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLEN 314
G L ML + G Y+C A+N G + + S+ +L P S+EN
Sbjct: 1205 GEDTYLLA----GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIEN 1257
Score = 80.5 bits (197), Expect = 2e-15
Identities = 67/209 (32%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G Y C + + L+V VP I N ++ EG + L C A G PEP +T
Sbjct: 2820 DAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT 2879
Query: 166 WRQLRDG---------FTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV 214
W +DG FT + GE+L + +++ AG Y C N V A RRV +T+
Sbjct: 2880 WD--KDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRA--RRRVHLTI 2934
Query: 215 NYPPTITDVTSART-ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
P T + R+ LG LRC A P W +DR ++ G +E +
Sbjct: 2935 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSE------QDGG 2988
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSA 302
S L A VS G Y C A NR+G + A
Sbjct: 2989 STLQRAAVSREDSGTYVCWAENRVGRTQA 3017
Score = 80.1 bits (196), Expect = 3e-15
Identities = 66/210 (31%), Positives = 85/210 (40%), Gaps = 14/210 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +V L DEG+YTC+ +V L V VP I V E +V L CLA G
Sbjct: 661 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 720
Query: 159 RPEPTVTWRQLRDGFTS--------EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
P P V+W + +S +G +L I Q AG Y CV N S R
Sbjct: 721 VPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST--ELRY 778
Query: 211 LVTVNYPPTITDVTS--ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
+ VN PP IT S + L C A P W KD +S GL+V
Sbjct: 779 GLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVF 838
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLG 298
+L A+ A G Y+C A + +G
Sbjct: 839 P--GGRVLTLASARASDSGRYSCVAVSAVG 866
Score = 79.0 bits (193), Expect = 6e-15
Identities = 83/297 (27%), Positives = 110/297 (37%), Gaps = 35/297 (11%)
Query: 38 PADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS- 96
P D V GD A LSC D L W D + +L +
Sbjct: 1847 PQDAVLVRVGDKAVLSCETDA-------------LPEPTVTWYKDGQPLVLAQRTQALRG 1893
Query: 97 ---ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGN-VNL 152
+ I E + D+GLY+C L V VP N + G+ + L
Sbjct: 1894 GQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVL 1953
Query: 153 LCLAVGRPEPTVTWRQLR--------DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204
C G P PTVTW + R G S G L++S +Q QAG Y CV N A
Sbjct: 1954 TCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN--TQA 2011
Query: 205 PDSRRVLVTVNYPPTITDVTSAR---TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ +V V P I AR G+ L CEA PP D W KD L
Sbjct: 2012 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 2071
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSA 316
L+ + L+ + A G YTC A N G A ++ +L P +++ A
Sbjct: 2072 GPHLRFYLD--GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 2126
Score = 77.4 bits (189), Expect = 2e-14
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 26/224 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV---NISSPVTVNEGGNVNLLCL 155
I + L D G Y C + L V+VP RI ++ PV VN V L C
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN 809
Query: 156 AVGRPEPTVTWRQLRDGFTSE------------GEILEISDIQRGQAGEYECVTHNGVNS 203
A G P PT+ W L+DG G +L ++ + +G Y CV + V
Sbjct: 810 ATGAPSPTLMW--LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 867
Query: 204 APDSRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
D + V++ V+ PP+I + + + L C++ A+PP W+KD R L
Sbjct: 868 --DRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPG 925
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V +++L G+YTC A N+ G S L
Sbjct: 926 ----VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNL 965
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/229 (28%), Positives = 91/229 (39%), Gaps = 23/229 (10%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVN----ISSPVTVNEGGNVNLLCLAVGRPEPT 163
G Y+C L+V P I+ + VTVN V+L C A+G P PT
Sbjct: 1626 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPT 1685
Query: 164 VTWRQLRDGFT--------SEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
++W Q F+ +G++L++S + A Y CV N SA + + V
Sbjct: 1686 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA--EKLFTLRVQ 1743
Query: 216 YPPTIT--DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP I D+ L + L C+ A P + WYKD + LS G L T
Sbjct: 1744 VPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH--- 1800
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENSAPRPP 320
L G YTC A N G ++L L P + APR P
Sbjct: 1801 -TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAF-RQAPRGP 1847
Score = 75.1 bits (183), Expect = 8e-14
Identities = 63/207 (30%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR 167
G YTCS + V+L V + + S V V L C A G P PT+TW+
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2791
Query: 168 Q----LRDGFTSE---GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI 220
+ + G +++ G L I+ AG Y C+ N SA R++V V PP I
Sbjct: 2792 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV--PPVI 2849
Query: 221 TD-VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFA 279
+ + T G A L C+A P + W KD + +S AEG T + LL
Sbjct: 2850 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG--AEG--KFTIQPSGELLVK 2905
Query: 280 NVSARHYGNYTCRAANRLGASSASMRL 306
N+ + G YTC A N +G + + L
Sbjct: 2906 NLEGQDAGTYTCTAENAVGRARRRVHL 2932
Score = 74.7 bits (182), Expect = 1e-13
Identities = 61/234 (26%), Positives = 92/234 (39%), Gaps = 12/234 (5%)
Query: 79 WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI 138
W D L + + S+ + VG GD G Y+C + L V P I +
Sbjct: 2249 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2308
Query: 139 SSP--VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS-EGEILEISDIQRGQAGEYEC 195
P +++ G + LLC A G P+P +TW + T E ++ AG Y C
Sbjct: 2309 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 2368
Query: 196 VTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRA---ALLRCEAMAVPPADFQWYK 252
+ + + S R V V PP I R +G A +L C A P W++
Sbjct: 2369 LAESPAGAIEKSFR--VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 2426
Query: 253 DDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
D +L E Q L +S G+Y+C A N G++S + R+
Sbjct: 2427 DGIVLQ----EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 2476
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/233 (26%), Positives = 89/233 (38%), Gaps = 18/233 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
++L+T G D + C + VHVP I + + TV V L C
Sbjct: 2629 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH 2688
Query: 156 AVGRPEPTVTWRQLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVNSAPDS 207
+ G P PTV+W + + G LEI AG Y C N A
Sbjct: 2689 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVA--H 2746
Query: 208 RRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+ V +TV P + + S R LL CEA +P W K+ +++G + +
Sbjct: 2747 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV- 2805
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL--RPGSLENSAP 317
L A+ S GNY C A N G++ RL+ P +EN P
Sbjct: 2806 ----LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 2854
Score = 72.8 bits (177), Expect = 4e-13
Identities = 54/187 (28%), Positives = 78/187 (41%), Gaps = 20/187 (10%)
Query: 147 GGNVNLLCLAVGRPEPTVTWRQLRDGFT---------SEGEILEISDIQRGQAGEYECVT 197
G +V L C G P P V W + R +G++L I+ G G Y+CV
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVA 291
Query: 198 HNGVNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
+ +R + V+ PPTI + L CEA VP + W+KD
Sbjct: 292 FSPAGQ--QARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDG 349
Query: 255 RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSL 312
LL + T KV R L + G YTC+A+N +GA+ + RL P ++
Sbjct: 350 ALLPTST----KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI 405
Query: 313 ENSAPRP 319
E + RP
Sbjct: 406 EGAGGRP 412
Score = 72.4 bits (176), Expect = 5e-13
Identities = 69/237 (29%), Positives = 100/237 (42%), Gaps = 28/237 (11%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI--VNISSPVTVNEGGNVNLL 153
++ I++V L D G++TC + L V VP + V + V V G V L
Sbjct: 2177 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2236
Query: 154 CLAVGRPEPTVTWRQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
C A G P P V+W ++DG +G L++ + G +G Y CV V+ A ++
Sbjct: 2237 CEARGVPLPLVSW--MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV---AVSEAGEA 2291
Query: 208 RR-VLVTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
RR +TV PP I D T G L C+A P + W+KD + L+
Sbjct: 2292 RRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR---- 2347
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPP 320
L+ + TR + R G YTC A + GA S R+ PR P
Sbjct: 2348 -LENNSRATRVL------RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGP 2397
Score = 72.0 bits (175), Expect = 7e-13
Identities = 70/241 (29%), Positives = 95/241 (39%), Gaps = 29/241 (12%)
Query: 79 WTSDPRVRLL----INTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPA 133
WT D + L + E+ +L IT +GDEG Y C + L VH P
Sbjct: 251 WTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPP 310
Query: 134 RI--VNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEGEILE 181
I N + V V E V LLC A G P P +TW +DG +T G L+
Sbjct: 311 TIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITW--FKDGALLPTSTKVVYTRGGRQLQ 368
Query: 182 ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTS----ARTALGRAALLR 237
+ Q AG Y C N V +A + R+ V V PPTI + GR L
Sbjct: 369 LGRAQSSDAGVYTCKASNAVGAAEKATRLDVYV--PPTIEGAGGRPYVVKAVAGRPVALE 426
Query: 238 CEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRL 297
C A P W+ + AE + + E S+L + G Y+C A++
Sbjct: 427 CVARGHPSPTLSWHHE----GLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPA 482
Query: 298 G 298
G
Sbjct: 483 G 483
Score = 67.4 bits (163), Expect = 2e-11
Identities = 71/271 (26%), Positives = 93/271 (34%), Gaps = 31/271 (11%)
Query: 40 DNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSIL 98
+ T + +L C + H V W S L G + V LL P ++
Sbjct: 1754 EQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE-------VFLL---PGTHTLQ 1803
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI----SSPVTVNEGGNVNLLC 154
+ L D G+YTC V L V VP V V G L C
Sbjct: 1804 LGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1863
Query: 155 LAVGRPEPTVTWRQ--------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
PEPTVTW + R G+ LEI + Q G Y C N A
Sbjct: 1864 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEA-- 1921
Query: 207 SRRVLVTVNYPPTITD--VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
R +TV PPT + + G +L C+ VP W KD + S G
Sbjct: 1922 VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHG 1981
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAAN 295
+ + R L + + G YTC A N
Sbjct: 1982 VVSRGGR----LQLSRLQPAQAGTYTCVAEN 2008
Score = 66.2 bits (160), Expect = 4e-11
Identities = 58/237 (24%), Positives = 89/237 (37%), Gaps = 24/237 (10%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVN--ISSPVTVNEGGNVNLLCLA 156
+T+ D GLY+C + V VP I N + + V +G +L+C
Sbjct: 1219 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 1278
Query: 157 VGRPEPTVTW----RQLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
G P+P +TW R L G + +G +L++ AG Y C+ N V ++
Sbjct: 1279 TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE--KTK 1336
Query: 209 RVLVTVNYPPTI------TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
++V PTI + + L CEA+A P + W KD +
Sbjct: 1337 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASR- 1395
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSAP 317
+Q L N G YTC N LG + + +L P S+ P
Sbjct: 1396 ---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 1449
Score = 64.7 bits (156), Expect = 1e-10
Identities = 60/221 (27%), Positives = 87/221 (39%), Gaps = 31/221 (14%)
Query: 106 DEGLYTCSFQTR----HQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
D G YTC + + Y V++ P R S +TV EG +L C G P
Sbjct: 944 DAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRE---SHTLTVREGHPTSLSCECRGVPF 1000
Query: 162 PTVTWRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
P ++WR +DG ++ G +L + Q Q G Y C N V ++ S+
Sbjct: 1001 PKISWR--KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS--SQD 1056
Query: 210 VLVTVNYPPTIT----DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+ + V+ PP I T A L C A PP W +D + + G GL
Sbjct: 1057 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGL 1114
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++Q + L A H G Y+C A N G + L
Sbjct: 1115 QLQNQ--GQSLHVERAQAAHTGRYSCVAENLAGRAERKFEL 1153
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/240 (25%), Positives = 89/240 (37%), Gaps = 46/240 (19%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-------SPVTVNEGGNVNLLCLAVG 158
D G YTC ++ V +P I V + L C +
Sbjct: 1415 DAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWA 1474
Query: 159 RPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
P PT+ W +DG EG +L+I Q +G Y CV N
Sbjct: 1475 VPPPTIRW--YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 1532
Query: 209 RVLVTVNYPPT---ITDVTSARTALGRA------------------ALLRCEAMAVPPAD 247
VL+ V PP + D ++A L R A L C+ A+PP D
Sbjct: 1533 NVLIQV--PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPD 1590
Query: 248 FQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
WY++D+ LS+G +V + +L V A + G Y+C+A+N +G LL
Sbjct: 1591 LTWYREDQPLSAGD----EVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELL 1646
Score = 58.5 bits (140), Expect = 8e-09
Identities = 59/222 (26%), Positives = 88/222 (39%), Gaps = 22/222 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHV---PARIVNISSPVTVNEGGNVNLLCLAVGRPEP 162
D G Y C + R TQ VHV P S + GG++ L C+ G P P
Sbjct: 3000 DSGTYVCWAENRVG--RTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 3057
Query: 163 TVTWRQLRDGFTSEGEILE---------ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVT 213
+ W ++DG G L I +R AG Y+C+ N + A +LV
Sbjct: 3058 DIHW--IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVV-ILVL 3114
Query: 214 VNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
+ P + G LRC+A P +W + + L + +++T
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR----RLRTLPDG 3170
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENS 315
S+ L NV G Y C A N LG+++A L+ G + S
Sbjct: 3171 SLWL-ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGS 3211
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/204 (28%), Positives = 77/204 (37%), Gaps = 17/204 (8%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLL--CLAVGRPEPT 163
D G Y+C+ R+ +T V V + S P VN N L C A G P P
Sbjct: 2455 DSGDYSCT--ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPL 2512
Query: 164 VTWRQLR---DGFTSEGEI-----LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
V+WR+ R D + EI L I + AG Y C+ N S R + V
Sbjct: 2513 VSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL-- 2570
Query: 216 YPPTITDVTSARTALGRA-ALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
PP I S T ALL CEA P W+KD + L +G +
Sbjct: 2571 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG--AYRLLPSN 2628
Query: 275 MLLFANVSARHYGNYTCRAANRLG 298
LL + + C +N +G
Sbjct: 2629 ALLLTAPGPQDSAQFECVVSNEVG 2652
Score = 51.2 bits (121), Expect = 1e-06
Identities = 37/130 (28%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-SPVTVNEGGNVNLLC 154
S+ I D G Y C + +V ++V A + + +TV G +V L C
Sbjct: 3081 SLTIHRTERDDAGRYQCLAENE-MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 3139
Query: 155 LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDS 207
A G P PT+ W Q + + L + +++ G AG Y+CV HN + SA +
Sbjct: 3140 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA-TA 3198
Query: 208 RRVLVTVNYP 217
R LV P
Sbjct: 3199 RAFLVVRGEP 3208
Score = 50.1 bits (118), Expect = 3e-06
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
Query: 154 CLAVGRPEPTVTWRQLRDGFTSEGE----ILE-----ISDIQRGQAGEYECVTHNGVNSA 204
C G P+P VTWR+ G+ +LE ++ + +G+YEC N V S
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGST 83
Query: 205 PDSRRVLVTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
SRR + V PP+I + + G++ L C+A P + W KD +L+
Sbjct: 84 --SRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLV 137
Score = 50.1 bits (118), Expect = 3e-06
Identities = 57/264 (21%), Positives = 90/264 (34%), Gaps = 26/264 (9%)
Query: 46 EGDNATLSCFI-DEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGL 104
EG +A L C + W + ++T P LL+ E
Sbjct: 2860 EGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEG---------- 2909
Query: 105 GDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTV 164
D G YTC+ + +V+L + V + ++ G + L C A G P P +
Sbjct: 2910 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 2969
Query: 165 TW----RQLRDGFTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218
W R + +G + + G L+ + + R +G Y C N V V V P
Sbjct: 2970 GWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAP 3027
Query: 219 TITDVTSARTA--LGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSML 276
+ + +G + L C P D W KD L G ++ + L
Sbjct: 3028 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-----RGSHLRHQLQNGSL 3082
Query: 277 LFANVSARHYGNYTCRAANRLGAS 300
G Y C A N +G +
Sbjct: 3083 TIHRTERDDAGRYQCLAENEMGVA 3106
Score = 49.3 bits (116), Expect = 5e-06
Identities = 57/234 (24%), Positives = 86/234 (36%), Gaps = 25/234 (10%)
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS--PVTVNEGGNVNLLCLAVGRP 160
G GLY+C + Q + V VP +++ VT G + L C A G P
Sbjct: 467 GEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP 526
Query: 161 EPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
PT+ W L++G S+G L I ++ +G + C N +A V
Sbjct: 527 VPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEV 584
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDR------LLSSGTAEG 264
V + P + +V + G A PP W + S G+ G
Sbjct: 585 SVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWG 644
Query: 265 LKVQTERTRSM---LLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLE 313
S+ L V R G YTC A N G S ++++L P ++E
Sbjct: 645 EPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 698
Score = 45.1 bits (105), Expect = 9e-05
Identities = 59/274 (21%), Positives = 88/274 (32%), Gaps = 51/274 (18%)
Query: 79 WTSDPRVRLLINTP-----EEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPA 133
W P L P EE S+ + V D G Y C + + L+V+VP
Sbjct: 36 WRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPP 95
Query: 134 RIVNISSPVTVN--EGGNVNLLCLAVGRPEPTVTWRQLRDG------------------- 172
I V+ G ++ L C A G P P + W L+D
Sbjct: 96 SIREDGRKANVSGMAGQSLTLECDANGFPVPEIVW--LKDAQLVGVPLGWAGYGWDLGWG 153
Query: 173 ------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNY---------- 216
EG+ L IQ G++G + L
Sbjct: 154 QVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPP 213
Query: 217 -PPTITDVTSARTALGRAAL---LRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERT 272
PP++ +A+ LG A L+C VP +W KD + + G G +Q +
Sbjct: 214 APPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPG---GPHLQVQED 270
Query: 273 RSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+L G Y C A + G + +L
Sbjct: 271 GQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQL 304
Score = 29.3 bits (64), Expect = 5.2
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 3/70 (4%)
Query: 238 CEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRL 297
C P W K G+ V E + L A+VS G+Y C+A N +
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS---LFLASVSPADSGDYECQATNEV 80
Query: 298 GASSASMRLL 307
G++S +L+
Sbjct: 81 GSTSRRAKLV 90
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/237 (29%), Positives = 103/237 (43%), Gaps = 27/237 (11%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP---VTVNEGGNVNLL 153
+ + + L EG YTC + + L VHVP +I P V+V + G L
Sbjct: 938 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLE 997
Query: 154 CLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
C A G+P PTVTW RDG ++G+ L + Q G Y CV N
Sbjct: 998 CNATGKPPPTVTWE--RDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGR 1055
Query: 204 APDSRRVLVTVNYPPTITD----VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSS 259
A R+ ++V PP + +T+ AL L CEAM +PP +W++ + +S
Sbjct: 1056 A--ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSP 1113
Query: 260 GTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLEN 314
G L ML + G Y+C A+N G + + S+ +L P S+EN
Sbjct: 1114 GEDTYLLA----GGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIEN 1166
Score = 87.4 bits (215), Expect = 2e-17
Identities = 79/304 (25%), Positives = 121/304 (39%), Gaps = 34/304 (11%)
Query: 41 NYTVCEGDNATLSCFIDEH-VTRVAWLNRSNIL--------YAGNDRWTSDPRVRLLINT 91
N + G + TL C + V + WL + ++ Y + W RLL
Sbjct: 27 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLL--- 83
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVN--EGGN 149
E S+ + GD GLY+C + + +L+V P ++ + V G +
Sbjct: 84 DEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGAD 143
Query: 150 VNLLCLAVGRPEPTVTWRQLRDGFT---------SEGEILEISDIQRGQAGEYECVTHNG 200
V L C G P P V W + R +G++L I+ G G Y+CV +
Sbjct: 144 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP 203
Query: 201 VNSAPDSRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
+R + V+ PPTI + L CEA VP + W+KD LL
Sbjct: 204 AGQ--QARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL 261
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENS 315
+ T KV R L + G YTC+A+N +GA+ + RL P ++E +
Sbjct: 262 PTST----KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGA 317
Query: 316 APRP 319
RP
Sbjct: 318 GGRP 321
Score = 80.5 bits (197), Expect = 2e-15
Identities = 67/209 (32%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G Y C + + L+V VP I N ++ EG + L C A G PEP +T
Sbjct: 2729 DAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNIT 2788
Query: 166 WRQLRDG---------FTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTV 214
W +DG FT + GE+L + +++ AG Y C N V A RRV +T+
Sbjct: 2789 WD--KDGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRA--RRRVHLTI 2843
Query: 215 NYPPTITDVTSART-ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
P T + R+ LG LRC A P W +DR ++ G +E +
Sbjct: 2844 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSE------QDGG 2897
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSA 302
S L A VS G Y C A NR+G + A
Sbjct: 2898 STLQRAAVSREDSGTYVCWAENRVGRTQA 2926
Score = 80.1 bits (196), Expect = 3e-15
Identities = 66/210 (31%), Positives = 85/210 (40%), Gaps = 14/210 (6%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +V L DEG+YTC+ +V L V VP I V E +V L CLA G
Sbjct: 570 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASG 629
Query: 159 RPEPTVTWRQLRDGFTS--------EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
P P V+W + +S +G +L I Q AG Y CV N S R
Sbjct: 630 VPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST--ELRY 687
Query: 211 LVTVNYPPTITDVTS--ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
+ VN PP IT S + L C A P W KD +S GL+V
Sbjct: 688 GLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVF 747
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLG 298
+L A+ A G Y+C A + +G
Sbjct: 748 P--GGRVLTLASARASDSGRYSCVAVSAVG 775
Score = 79.0 bits (193), Expect = 6e-15
Identities = 83/297 (27%), Positives = 110/297 (37%), Gaps = 35/297 (11%)
Query: 38 PADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS- 96
P D V GD A LSC D L W D + +L +
Sbjct: 1756 PQDAVLVRVGDKAVLSCETDA-------------LPEPTVTWYKDGQPLVLAQRTQALRG 1802
Query: 97 ---ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGN-VNL 152
+ I E + D+GLY+C L V VP N + G+ + L
Sbjct: 1803 GQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVL 1862
Query: 153 LCLAVGRPEPTVTWRQLR--------DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204
C G P PTVTW + R G S G L++S +Q QAG Y CV N A
Sbjct: 1863 TCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN--TQA 1920
Query: 205 PDSRRVLVTVNYPPTITDVTSAR---TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ +V V P I AR G+ L CEA PP D W KD L
Sbjct: 1921 EARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM 1980
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSA 316
L+ + L+ + A G YTC A N G A ++ +L P +++ A
Sbjct: 1981 GPHLRFYLD--GGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGA 2035
Score = 77.0 bits (188), Expect = 2e-14
Identities = 62/224 (27%), Positives = 92/224 (41%), Gaps = 26/224 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV---NISSPVTVNEGGNVNLLCL 155
I + L D G Y C + L V+VP RI ++ PV VN V L C
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTP--VRLTCN 718
Query: 156 AVGRPEPTVTWRQLRDGFTSE------------GEILEISDIQRGQAGEYECVTHNGVNS 203
A G P PT+ W L+DG G +L ++ + +G Y CV + V
Sbjct: 719 ATGAPSPTLMW--LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 776
Query: 204 APDSRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
D + V++ V+ PP+I + + + L C++ A+PP W+KD R L
Sbjct: 777 --DRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPG 834
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V +++L G+YTC A N+ G S L
Sbjct: 835 ----VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNL 874
Score = 77.0 bits (188), Expect = 2e-14
Identities = 66/229 (28%), Positives = 91/229 (39%), Gaps = 23/229 (10%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVN----ISSPVTVNEGGNVNLLCLAVGRPEPT 163
G Y+C L+V P I+ + VTVN V+L C A+G P PT
Sbjct: 1535 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPT 1594
Query: 164 VTWRQLRDGFT--------SEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
++W Q F+ +G++L++S + A Y CV N SA + + V
Sbjct: 1595 ISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA--EKLFTLRVQ 1652
Query: 216 YPPTIT--DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
PP I D+ L + L C+ A P + WYKD + LS G L T
Sbjct: 1653 VPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH--- 1709
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENSAPRPP 320
L G YTC A N G ++L L P + APR P
Sbjct: 1710 -TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAF-RQAPRGP 1756
Score = 75.1 bits (183), Expect = 8e-14
Identities = 63/207 (30%), Positives = 90/207 (43%), Gaps = 14/207 (6%)
Query: 108 GLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR 167
G YTCS + V+L V + + S V V L C A G P PT+TW+
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2700
Query: 168 Q----LRDGFTSE---GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI 220
+ + G +++ G L I+ AG Y C+ N SA R++V V PP I
Sbjct: 2701 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQV--PPVI 2758
Query: 221 TD-VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFA 279
+ + T G A L C+A P + W KD + +S AEG T + LL
Sbjct: 2759 ENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG--AEG--KFTIQPSGELLVK 2814
Query: 280 NVSARHYGNYTCRAANRLGASSASMRL 306
N+ + G YTC A N +G + + L
Sbjct: 2815 NLEGQDAGTYTCTAENAVGRARRRVHL 2841
Score = 74.7 bits (182), Expect = 1e-13
Identities = 61/234 (26%), Positives = 92/234 (39%), Gaps = 12/234 (5%)
Query: 79 WTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI 138
W D L + + S+ + VG GD G Y+C + L V P I +
Sbjct: 2158 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2217
Query: 139 SSP--VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTS-EGEILEISDIQRGQAGEYEC 195
P +++ G + LLC A G P+P +TW + T E ++ AG Y C
Sbjct: 2218 GQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLRVRDAGLYTC 2277
Query: 196 VTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRA---ALLRCEAMAVPPADFQWYK 252
+ + + S R V V PP I R +G A +L C A P W++
Sbjct: 2278 LAESPAGAIEKSFR--VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 2335
Query: 253 DDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
D +L E Q L +S G+Y+C A N G++S + R+
Sbjct: 2336 DGIVLQ----EDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 2385
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/233 (26%), Positives = 89/233 (38%), Gaps = 18/233 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
++L+T G D + C + VHVP I + + TV V L C
Sbjct: 2538 ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCH 2597
Query: 156 AVGRPEPTVTWRQLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVNSAPDS 207
+ G P PTV+W + + G LEI AG Y C N A
Sbjct: 2598 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVA--H 2655
Query: 208 RRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+ V +TV P + + S R LL CEA +P W K+ +++G + +
Sbjct: 2656 KHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV- 2714
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL--RPGSLENSAP 317
L A+ S GNY C A N G++ RL+ P +EN P
Sbjct: 2715 ----LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 2763
Score = 72.4 bits (176), Expect = 5e-13
Identities = 69/237 (29%), Positives = 100/237 (42%), Gaps = 28/237 (11%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI--VNISSPVTVNEGGNVNLL 153
++ I++V L D G++TC + L V VP + V + V V G V L
Sbjct: 2086 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2145
Query: 154 CLAVGRPEPTVTWRQLRDG------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
C A G P P V+W ++DG +G L++ + G +G Y CV V+ A ++
Sbjct: 2146 CEARGVPLPLVSW--MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCV---AVSEAGEA 2200
Query: 208 RR-VLVTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
RR +TV PP I D T G L C+A P + W+KD + L+
Sbjct: 2201 RRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR---- 2256
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPP 320
L+ + TR + R G YTC A + GA S R+ PR P
Sbjct: 2257 -LENNSRATRVL------RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGP 2306
Score = 67.4 bits (163), Expect = 2e-11
Identities = 71/271 (26%), Positives = 93/271 (34%), Gaps = 31/271 (11%)
Query: 40 DNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSIL 98
+ T + +L C + H V W S L G + V LL P ++
Sbjct: 1663 EQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE-------VFLL---PGTHTLQ 1712
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI----SSPVTVNEGGNVNLLC 154
+ L D G+YTC V L V VP V V G L C
Sbjct: 1713 LGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1772
Query: 155 LAVGRPEPTVTWRQ--------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
PEPTVTW + R G+ LEI + Q G Y C N A
Sbjct: 1773 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEA-- 1830
Query: 207 SRRVLVTVNYPPTITD--VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
R +TV PPT + + G +L C+ VP W KD + S G
Sbjct: 1831 VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHG 1890
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAAN 295
+ + R L + + G YTC A N
Sbjct: 1891 VVSRGGR----LQLSRLQPAQAGTYTCVAEN 1917
Score = 66.2 bits (160), Expect = 4e-11
Identities = 58/237 (24%), Positives = 89/237 (37%), Gaps = 24/237 (10%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVN--ISSPVTVNEGGNVNLLCLA 156
+T+ D GLY+C + V VP I N + + V +G +L+C
Sbjct: 1128 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 1187
Query: 157 VGRPEPTVTW----RQLRDG----FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
G P+P +TW R L G + +G +L++ AG Y C+ N V ++
Sbjct: 1188 TGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGE--KTK 1245
Query: 209 RVLVTVNYPPTI------TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
++V PTI + + L CEA+A P + W KD +
Sbjct: 1246 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASR- 1304
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG--ASSASMRLLRPGSLENSAP 317
+Q L N G YTC N LG + + +L P S+ P
Sbjct: 1305 ---NIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDP 1358
Score = 64.7 bits (156), Expect = 1e-10
Identities = 62/221 (28%), Positives = 86/221 (38%), Gaps = 31/221 (14%)
Query: 106 DEGLYTCSF--QTRHQP--YTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
D G YTC Q H Y V++ P R S +TV EG L C G P
Sbjct: 853 DAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRE---SHTLTVREGHPTRLSCECRGVPF 909
Query: 162 PTVTWRQLRDG------------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
P ++WR +DG ++ G +L + Q Q G Y C N V ++ S+
Sbjct: 910 PKISWR--KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS--SQD 965
Query: 210 VLVTVNYPPTIT----DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+ + V+ PP I T A L C A PP W +D + + G GL
Sbjct: 966 LQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGL 1023
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++Q + L A H G Y+C A N G + L
Sbjct: 1024 QLQNQ--GQSLHVERAQAAHTGRYSCVAENLAGRAERKFEL 1062
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/240 (25%), Positives = 89/240 (37%), Gaps = 46/240 (19%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-------SPVTVNEGGNVNLLCLAVG 158
D G YTC ++ V +P I V + L C +
Sbjct: 1324 DAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWA 1383
Query: 159 RPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
P PT+ W +DG EG +L+I Q +G Y CV N
Sbjct: 1384 VPPPTIRW--YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDF 1441
Query: 209 RVLVTVNYPPT---ITDVTSARTALGRA------------------ALLRCEAMAVPPAD 247
VL+ V PP + D ++A L R A L C+ A+PP D
Sbjct: 1442 NVLIQV--PPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPD 1499
Query: 248 FQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
WY++D+ LS+G +V + +L V A + G Y+C+A+N +G LL
Sbjct: 1500 LTWYREDQPLSAGD----EVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELL 1555
Score = 62.4 bits (150), Expect = 6e-10
Identities = 63/231 (27%), Positives = 88/231 (38%), Gaps = 33/231 (14%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS-PVTVNE--GGNVNLLCLAVGRPEP 162
D G+YTC L V+VP I P V G V L C+A G P P
Sbjct: 285 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 344
Query: 163 TVTW--------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL--- 211
T++W ++G +L + +G Y CV S+P VL
Sbjct: 345 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-----SSPAGEAVLQYS 399
Query: 212 VTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK-V 267
V V PP + + T +G+ L C+A P QW ++ R AE L V
Sbjct: 400 VEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGR-----PAEELAGV 454
Query: 268 QTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL-----LRPGSLE 313
Q + L +V H G + C+A N G + A + + PG LE
Sbjct: 455 QVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLE 505
Score = 58.5 bits (140), Expect = 8e-09
Identities = 59/222 (26%), Positives = 88/222 (39%), Gaps = 22/222 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHV---PARIVNISSPVTVNEGGNVNLLCLAVGRPEP 162
D G Y C + R TQ VHV P S + GG++ L C+ G P P
Sbjct: 2909 DSGTYVCWAENRVG--RTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVP 2966
Query: 163 TVTWRQLRDGFTSEGEILE---------ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVT 213
+ W ++DG G L I +R AG Y+C+ N + A +LV
Sbjct: 2967 DIHW--IKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVV-ILVL 3023
Query: 214 VNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTR 273
+ P + G LRC+A P +W + + L + +++T
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR----RLRTLPDG 3079
Query: 274 SMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENS 315
S+ L NV G Y C A N LG+++A L+ G + S
Sbjct: 3080 SLWL-ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGS 3120
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/204 (28%), Positives = 77/204 (37%), Gaps = 17/204 (8%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLL--CLAVGRPEPT 163
D G Y+C+ R+ +T V V + S P VN N L C A G P P
Sbjct: 2364 DSGDYSCT--ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPL 2421
Query: 164 VTWRQLR---DGFTSEGEI-----LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
V+WR+ R D + EI L I + AG Y C+ N S R + V
Sbjct: 2422 VSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL-- 2479
Query: 216 YPPTITDVTSARTALGRA-ALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
PP I S T ALL CEA P W+KD + L +G +
Sbjct: 2480 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQG--AYRLLPSN 2537
Query: 275 MLLFANVSARHYGNYTCRAANRLG 298
LL + + C +N +G
Sbjct: 2538 ALLLTAPGPQDSAQFECVVSNEVG 2561
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/130 (28%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-SPVTVNEGGNVNLLC 154
S+ I D G Y C + +V ++V A + + +TV G +V L C
Sbjct: 2990 SLTIRRTERDDAGRYQCLAENE-MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRC 3048
Query: 155 LAVGRPEPTVTWRQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDS 207
A G P PT+ W Q + + L + +++ G AG Y+CV HN + SA +
Sbjct: 3049 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA-TA 3107
Query: 208 RRVLVTVNYP 217
R LV P
Sbjct: 3108 RAFLVVRGEP 3117
Score = 50.4 bits (119), Expect = 2e-06
Identities = 57/264 (21%), Positives = 90/264 (34%), Gaps = 26/264 (9%)
Query: 46 EGDNATLSCFI-DEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGL 104
EG +A L C + W + ++T P LL+ E
Sbjct: 2769 EGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEG---------- 2818
Query: 105 GDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTV 164
D G YTC+ + +V+L + V + ++ G + L C A G P P +
Sbjct: 2819 QDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRI 2878
Query: 165 TW----RQLRDGFTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP 218
W R + +G + + G L+ + + R +G Y C N V V V P
Sbjct: 2879 GWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEAP 2936
Query: 219 TITDVTSARTA--LGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSML 276
+ + +G + L C P D W KD L G ++ + L
Sbjct: 2937 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-----RGSHLRHQLQNGSL 2991
Query: 277 LFANVSARHYGNYTCRAANRLGAS 300
G Y C A N +G +
Sbjct: 2992 TIRRTERDDAGRYQCLAENEMGVA 3015
Score = 49.3 bits (116), Expect = 5e-06
Identities = 57/234 (24%), Positives = 86/234 (36%), Gaps = 25/234 (10%)
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISS--PVTVNEGGNVNLLCLAVGRP 160
G GLY+C + Q + V VP +++ VT G + L C A G P
Sbjct: 376 GEASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSP 435
Query: 161 EPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
PT+ W L++G S+G L I ++ +G + C N +A V
Sbjct: 436 VPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEV 493
Query: 211 LVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDR------LLSSGTAEG 264
V + P + +V + G A PP W + S G+ G
Sbjct: 494 SVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWG 553
Query: 265 LKVQTERTRSM---LLFANVSARHYGNYTCRAANRLGAS--SASMRLLRPGSLE 313
S+ L V R G YTC A N G S ++++L P ++E
Sbjct: 554 EPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 607
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 85.9 bits (211), Expect = 5e-17
Identities = 81/314 (25%), Positives = 122/314 (38%), Gaps = 36/314 (11%)
Query: 17 ALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCF-IDEHVTRVAWLNRSNILYAG 75
A LA L + S++ PA+ Y + G TL CF V R+ W L
Sbjct: 225 AQLNLAAEDTRLFAPSIKARFPAETYALV-GQQVTLECFAFGNPVPRIKWRKVDGSL--- 280
Query: 76 NDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI 135
+ +WT+ E ++ I V DEG Y C + T Q +IV
Sbjct: 281 SPQWTT-----------AEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEW 329
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEI------LEISDIQRGQ 189
+ + S + G N+ C A G+P PTV W + + S+ + L S +
Sbjct: 330 LKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSLED 389
Query: 190 AGEYECVTHNGVNSAPDSRRVLVTVNYP-----PTITDVTSARTALGRAALLRCEAMAVP 244
+G Y+CV N + S + V P P + +AR G L+ C+ A P
Sbjct: 390 SGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAAR---GGEILIPCQPRAAP 446
Query: 245 PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG-ASSAS 303
A W K +L + + T L+ N+S G YTC A N +G A+S
Sbjct: 447 KAVVLWSKGTEILVNSSR-----VTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTG 501
Query: 304 MRLLRPGSLENSAP 317
+ +R + AP
Sbjct: 502 ILSVRDATKITLAP 515
Score = 62.8 bits (151), Expect = 4e-10
Identities = 68/274 (24%), Positives = 102/274 (37%), Gaps = 34/274 (12%)
Query: 63 VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYT 122
V WL L + N RV +L + +++ L D G+Y C + +H
Sbjct: 358 VRWLRNGEPLASQN-------RVEVLAG-----DLRFSKLSLEDSGMYQCVAENKHGTIY 405
Query: 123 TQVYLIVHVPA---RIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQ--------LRD 171
L V A R+ + + GG + + C P+ V W + R
Sbjct: 406 ASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRV 465
Query: 172 GFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALG 231
T +G ++ I +I R G+Y C N + A +S +L + +SA LG
Sbjct: 466 TVTPDGTLI-IRNISRSDEGKYTCFAENFMGKA-NSTGILSVRDATKITLAPSSADINLG 523
Query: 232 RAALLRCEAMAVPPAD--FQWYKDDRLLSSGTAEG--LKVQTERTRSMLLFANVSARHYG 287
L+C A P D F W DD + G + + T L N RH G
Sbjct: 524 DNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGG 583
Query: 288 NYTCRAANRLGASSASMRLLRPGSLENSAPRPPG 321
YTC A + ++S +L G P PPG
Sbjct: 584 KYTCMAQTVVDSASKEATVLVRG-----PPGPPG 612
Score = 32.3 bits (72), Expect = 0.61
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 7/81 (8%)
Query: 235 LLRCEAMAVPPADFQWYKD--DRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCR 292
LL C A A PPA ++W + + L G+ L ++++ A+ G Y C
Sbjct: 58 LLACRARASPPATYRWKMNGTEMKLEPGSRHQLV-----GGNLVIMNPTKAQDAGVYQCL 112
Query: 293 AANRLGASSASMRLLRPGSLE 313
A+N +G + +LR G L+
Sbjct: 113 ASNPVGTVVSREAILRFGFLQ 133
Score = 32.0 bits (71), Expect = 0.80
Identities = 36/168 (21%), Positives = 63/168 (37%), Gaps = 17/168 (10%)
Query: 150 VNLLCLAVGRPEPTVTWR------QLRDGFTSE---GEILEISDIQRGQAGEYECVTHNG 200
V L C A P T W+ +L G + G ++ ++ + AG Y+C+ N
Sbjct: 57 VLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNP 116
Query: 201 VNSAPDSRRVL---VTVNYPPTITDVTSARTALGRAALLRCEAMA-VPPADFQWYKDDRL 256
V + +L + D A G +L C A P ++W ++
Sbjct: 117 VGTVVSREAILRFGFLQEFSKEERDPVKAHEGWG--VMLPCNPPAHYPGLSYRWLLNE-- 172
Query: 257 LSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
+ + +T L A +A GNY+C A + + S+ S+
Sbjct: 173 FPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSV 220
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 85.5 bits (210), Expect = 6e-17
Identities = 71/282 (25%), Positives = 116/282 (41%), Gaps = 42/282 (14%)
Query: 41 NYTVCEGDNATLSCFID-EHVTRVAWLNRSNILYAGNDRW-----TSDPRVRLLINTPEE 94
N T G+ T SC ++W R+ L N+++ ++ VR +IN+
Sbjct: 219 NATAERGEEMTFSCRASGSPEPAISWF-RNGKLIEENEKYILKGSNTELTVRNIINS--- 274
Query: 95 FSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLC 154
D G Y C + Q +L V V I+ + + T E G V L+C
Sbjct: 275 -----------DGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTY-ENGQVTLVC 322
Query: 155 LAVGRPEPTVTWRQLRDGFT-SEGE----------------ILEISDIQRGQAGEYECVT 197
A G P P +TW++ DGFT +EG+ L I D++ +G Y+C
Sbjct: 323 DAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEA 382
Query: 198 HNGVNSAPDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRL 256
+ + S + + + Y P I++ T + G + C+ + PPA W +D +
Sbjct: 383 ASRIGGHQKS--MYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLV 440
Query: 257 LSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
L + LK + + +L A S +G Y C A N +G
Sbjct: 441 LPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 68.6 bits (166), Expect = 8e-12
Identities = 71/297 (23%), Positives = 116/297 (39%), Gaps = 35/297 (11%)
Query: 31 QSLEFNSPADNYTVCEGDNATLSCFIDEH-VTRVAWLNRSNILYAGNDRWTSDPRVRLLI 89
Q L F +G++A + C + V+WL + + SD R +L
Sbjct: 113 QKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTT-----ISDNRFAMLA 167
Query: 90 NTPEEFSILITEVGLGDEGLYTCS--FQTRHQPYTTQVYLIVHVPARIV--NISSPVTVN 145
N ++ I + DEG+Y C + R + + +IV+VP I S T
Sbjct: 168 NN----NLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAE 223
Query: 146 EGGNVNLLCLAVGRPEPTVTW-----------RQLRDGFTSEGEILEISDIQRGQAGEYE 194
G + C A G PEP ++W + + G +E L + +I G Y
Sbjct: 224 RGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTE---LTVRNIINSDGGPYV 280
Query: 195 CVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYK-- 252
C N + D ++ + V P I + + T L C+A P + W +
Sbjct: 281 CRATN--KAGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAV 338
Query: 253 DDRLLSSG--TAEG-LKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
D + G + +G ++V+ + S L +V G Y C AA+R+G SM L
Sbjct: 339 DGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYL 395
Score = 65.5 bits (158), Expect = 7e-11
Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 17/215 (7%)
Query: 97 ILITEVGLGDEGLYTC-SFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
+ I + D G+Y C + + Q V L ++ + SP +G + ++C
Sbjct: 78 LTIYNANIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEFKQGEDAEVVCR 137
Query: 156 AVGRPEPTVTWRQLRDGFTSEGEI---------LEISDIQRGQAGEYECVTHNGVNSAPD 206
P P V+W + T+ + L+I +I + G Y C D
Sbjct: 138 VSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEID 197
Query: 207 SRRVLVTVNYPPTIT---DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
R ++V VN PP I+ +A G C A P W+++ +L+ E
Sbjct: 198 FRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIE----E 253
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
K + + + L N+ G Y CRA N+ G
Sbjct: 254 NEKYILKGSNTELTVRNIINSDGGPYVCRATNKAG 288
Score = 44.3 bits (103), Expect = 2e-04
Identities = 39/177 (22%), Positives = 66/177 (37%), Gaps = 16/177 (9%)
Query: 41 NYTVCEGDNATLSCFID-EHVTRVAWLNR-SNILYAGNDRWTSDPRVRLLINTPEEFSIL 98
N T E TL C + E + + W + D+ + D R+ + S+
Sbjct: 309 NETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDK-SLDGRIEVK-GQHGSSSLH 366
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +V L D G Y C +R + +YL + + ++ + EG +N+ C
Sbjct: 367 IKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKS 426
Query: 159 RPEPTVTWRQ------------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
P ++ WR+ L+ T ILEI+ G Y C N + +
Sbjct: 427 NPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGT 483
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 85.1 bits (209), Expect = 8e-17
Identities = 61/209 (29%), Positives = 87/209 (41%), Gaps = 16/209 (7%)
Query: 107 EGLYTCSFQTRHQPYTTQVYLIVH-VPARIVNISSPV-TVNEGGNVNLLCLAVGRPEPTV 164
+G Y C L++ +P+ ++NI + V TV G V CLA+G P+P V
Sbjct: 3461 QGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQV 3520
Query: 165 TWRQ----LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI 220
TW + LR G G ++ I+ ++ AG+Y C N + VL+ V P I
Sbjct: 3521 TWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTT--QSHVLLLVQALPQI 3578
Query: 221 TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFAN 280
+ R G AA+ C A P D W K D L + +ML+ +
Sbjct: 3579 SMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLD--------GSLPPDSRLENNMLMLPS 3630
Query: 281 VSARHYGNYTCRAANRLGASSASMRLLRP 309
V + G Y C A NR G A L P
Sbjct: 3631 VRPQDAGTYVCTATNRQGKVKAFAHLQVP 3659
Score = 78.2 bits (191), Expect = 1e-14
Identities = 65/233 (27%), Positives = 90/233 (38%), Gaps = 29/233 (12%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPA------RIVNISSPVTVNEGGNVNLLCLAVGR 159
D G Y C Q QV +IV A ++ + +TV G L C A G
Sbjct: 3179 DAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGS 3238
Query: 160 PEPTVTWRQLRDGF----TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
P PT+ W +LR EG+ L I + + +G+Y C + A +++ V
Sbjct: 3239 PAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHA--EATIILHVE 3296
Query: 216 YPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRS 274
PP T V A G L+C A PP FQW S L +
Sbjct: 3297 SPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQW--------SRVGSSLPGRATARNE 3348
Query: 275 MLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGLLALLS 327
+L F + G Y CR N++G++ A +LL G PPG L S
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQG--------PPGSLPATS 3393
Score = 67.4 bits (163), Expect = 2e-11
Identities = 79/291 (27%), Positives = 112/291 (38%), Gaps = 32/291 (10%)
Query: 44 VCEGDNATLSCFIDEHV-TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEV 102
V EG L+C + +V W R L A + S R+RLL TP + + V
Sbjct: 2448 VAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGS--RLRLLQVTPADSGEYVCRV 2505
Query: 103 GLGDEGLYTCS-FQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
+G G S T Q + V P RI SS ++ G ++L CL +
Sbjct: 2506 -VGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIE--SSSASLANGHTLDLNCLVASQAP 2562
Query: 162 PTVTWRQLRDGFTSEGEI----LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN-- 215
T+TW + S +I L I + +GEY C NG S S ++VT+
Sbjct: 2563 HTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETS--LIVTIQGS 2620
Query: 216 --------YPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKV 267
PP + +S G+ L C P A WYK L S
Sbjct: 2621 GSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPS-------- 2672
Query: 268 QTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL-LRPGSLENSAP 317
+ + S L +S G Y CRA N + A AS+ + + P + SAP
Sbjct: 2673 RHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAP 2723
Score = 66.6 bits (161), Expect = 3e-11
Identities = 65/282 (23%), Positives = 99/282 (35%), Gaps = 38/282 (13%)
Query: 43 TVCEGDNATLSCFIDEHVTRVA--WLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILIT 100
TV +G +A+ C I + ++ W R+ L + V + +P I I
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLEWKTRNQEL---------EDNVHI---SPNGSIITIV 3079
Query: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARI-VNISSPVTVNEGGNVNLLCLAVGR 159
+ G Y C + + V L VH P + V PV V G V L C++ G
Sbjct: 3080 GTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGE 3139
Query: 160 PEPTVTWRQLRD----------GFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
P + W ++ G +L+IS + AG Y C+ N + +A
Sbjct: 3140 PRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVE 3199
Query: 210 VLVTV-----NYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
V+V P + G A LRC A P W K
Sbjct: 3200 VIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSK--------LRSP 3251
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
L Q L+ V+ + G Y C A + G + A++ L
Sbjct: 3252 LPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIIL 3293
Score = 60.8 bits (146), Expect = 2e-09
Identities = 62/234 (26%), Positives = 93/234 (39%), Gaps = 20/234 (8%)
Query: 97 ILITEVGLGDEGLYTCS----FQTRHQPYTTQVYLIVHVPARIVNISSP-VTVNEGGNVN 151
+ I V L D G Y C+ F T V + A +V+I P +TV G
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAE 1884
Query: 152 LLCLAVGRPEPTVTWR-----QLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
C A G P PT+ W QL G IL + ++ +Y C H+
Sbjct: 1885 FRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQV- 1943
Query: 207 SRRVLVTVNYPPTITDVTSARTAL--GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
+R VL V+ RT + GR L C A VP A W K+ G +
Sbjct: 1944 ARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKE------GGSLP 1997
Query: 265 LKVQTERTR-SMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAP 317
+ ++ERT + LL ++ G Y C A + G + A ++++ + + S P
Sbjct: 1998 PQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPP 2051
Score = 57.8 bits (138), Expect = 1e-08
Identities = 74/324 (22%), Positives = 116/324 (35%), Gaps = 68/324 (20%)
Query: 33 LEFNSPADNYTVCEGDNATLSCFIDEHVTRV-AWLNRSNILYAGNDRWTSDPRVRLLINT 91
+E +SP TV EG L+C + + W R L + + S R+
Sbjct: 2634 IESSSP----TVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLH----- 2684
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVH------------VPARIVNIS 139
++ + D G Y C + + V +P RI + S
Sbjct: 2685 ---------QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSS 2735
Query: 140 SPVTVNEGGNVNLLCLAVGRPEPTVTWRQ----LRDGFTSEGEILEISDIQRGQAGEYEC 195
S V EG ++L C+ G+ VTW + L + G L + + +GEY C
Sbjct: 2736 SHVA--EGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVC 2793
Query: 196 VTHNGVNSAPDSRRVLVTVNY--------------PPTITDVTSARTALGRAALLRCEAM 241
+S P VLVT+ PP + +S+R A G+ L+C
Sbjct: 2794 RVMG--SSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVP 2851
Query: 242 AVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASS 301
A W+K L + + +L VS G Y+C+ G
Sbjct: 2852 GQAHAQVTWHK--------RGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLE 2903
Query: 302 ASMRLLRPGSLENSAPRP---PGL 322
AS+ + ++E S+P P PGL
Sbjct: 2904 ASVLV----TIEPSSPGPIPAPGL 2923
Score = 56.6 bits (135), Expect = 3e-08
Identities = 66/295 (22%), Positives = 118/295 (40%), Gaps = 27/295 (9%)
Query: 39 ADNYTVCEGDNATLSCFIDEHV-TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSI 97
A + V EG L+C + +V W R L A + T ++RL + +P +
Sbjct: 2931 ASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQ--THGSQLRLHLVSPADSGE 2988
Query: 98 LITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPV-TVNEGGNVNLLCLA 156
+ G SF P Y + + +++I P TV +G + + CL
Sbjct: 2989 YVCRAASGPGPEQEASFTVTVPPSEGSSY---RLRSPVISIDPPSSTVQQGQDASFKCLI 3045
Query: 157 VGRPEP-TVTWR----QLRDG--FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRR 209
P ++ W+ +L D + G I+ I + G Y CV N A
Sbjct: 3046 HDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSV-- 3103
Query: 210 VLVTVNYPPTITDVTSART--ALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKV 267
V ++V+ PPT++ + +G+A L C + P + +W + S T L+
Sbjct: 3104 VNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTR-----ISSTPAKLEQ 3158
Query: 268 QTER---TRSMLLFANVSARHYGNYTCRAANRLGASSASMR-LLRPGSLENSAPR 318
+T + ++L ++ G Y C A N LG + + ++ G++ AP+
Sbjct: 3159 RTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQ 3213
Score = 56.2 bits (134), Expect = 4e-08
Identities = 53/229 (23%), Positives = 83/229 (36%), Gaps = 25/229 (10%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
+++I V D G Y C+ + + L V P + +V G V L CL
Sbjct: 3262 TLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCL 3321
Query: 156 AVGRPEPTVTWRQLRDGF----TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVL 211
A G P T W ++ T+ E+L +G Y C N V SA ++L
Sbjct: 3322 AHGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 212 V------------TVNYPPTITDVTSART-ALGRAALLRCEAMAVPPADFQWYKDDRLLS 258
V PT+ T ++G + C + +W+K+ L
Sbjct: 3382 VQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLP 3441
Query: 259 SGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLL 307
G + VQ +L N+ G Y C+A G + AS +L+
Sbjct: 3442 PGHS----VQD----GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLV 3482
Score = 55.8 bits (133), Expect = 5e-08
Identities = 63/241 (26%), Positives = 83/241 (34%), Gaps = 24/241 (9%)
Query: 79 WTSDPRVRLLINTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPA--RI 135
WT P +L IL + V D+ Y C + + L VH R+
Sbjct: 1899 WTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Query: 136 VNISSPVTVNEGGNVNLLCLAVGRPEPTVTWR--------QLRDGFTSEGEILEISDIQR 187
V+ G V L C A G P T+TWR Q R T +L I I
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLL-IPAITT 2017
Query: 188 GQAGEYECVTHNGVNSAPDSRRVLV----TVNYPPTITDVTSARTALGRAALLRCEAMAV 243
AG Y CV + +A +V+V + PP + +S G+ L C
Sbjct: 2018 ADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGS 2077
Query: 244 PPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
A WY+ L T+ S L VS G Y CR N G AS
Sbjct: 2078 AHAQVTWYR--------RGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEAS 2129
Query: 304 M 304
+
Sbjct: 2130 I 2130
Score = 55.8 bits (133), Expect = 5e-08
Identities = 72/291 (24%), Positives = 105/291 (36%), Gaps = 33/291 (11%)
Query: 44 VCEGDNATLSCFID-EHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEV 102
V EG L+C + + +V W R L + T +RL +P + + V
Sbjct: 2352 VAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQ--THGSLLRLYQASPADSGEYVCRV 2409
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEP 162
LG S +P + L V RI + SS V EG ++L CL G+
Sbjct: 2410 -LGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVA--EGQTLDLNCLVAGQAHA 2466
Query: 163 TVTWRQLRDGFTS----EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN--- 215
VTW + + G L + + +GEY C +S VLVT+
Sbjct: 2467 QVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVG--SSGTQEASVLVTIQQRL 2524
Query: 216 ---------YPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
YP I + +SA A G L C + P WYK L S
Sbjct: 2525 SGSHSQGVAYPVRI-ESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPS------- 2576
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAP 317
+ + S L V+ G Y C +N G+ S+ + GS + P
Sbjct: 2577 -RHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVP 2626
Score = 53.9 bits (128), Expect = 2e-07
Identities = 71/283 (25%), Positives = 100/283 (35%), Gaps = 58/283 (20%)
Query: 44 VCEGDNATLSCFIDEHV-TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEV 102
V EG L+C + +V W R L A + T +RL TP
Sbjct: 2163 VAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQ--THGSLLRLHQVTP---------- 2210
Query: 103 GLGDEGLYTCSFQTRHQPYTTQVYLIVHV--------PARIVNISSPVTVNEGGNVNLLC 154
D G Y C P V + + P RI + SS TV EG ++L C
Sbjct: 2211 --ADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSS--TVAEGQTLDLSC 2266
Query: 155 LAVGRPEPTVTWRQLRDGFTS----EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRV 210
+ G+ VTW + + G L I AG+Y C NG+ ++ +
Sbjct: 2267 VVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEAS-----I 2321
Query: 211 LVTVN--------YP-----PTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLL 257
VTV YP P + +S++ A G+ L C A W+K
Sbjct: 2322 TVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHK----- 2376
Query: 258 SSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS 300
L V+ + S+L S G Y CR LG+S
Sbjct: 2377 ---RGGSLPVRHQTHGSLLRLYQASPADSGEYVCRV---LGSS 2413
Score = 52.4 bits (124), Expect = 6e-07
Identities = 54/224 (24%), Positives = 83/224 (37%), Gaps = 46/224 (20%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIV-HVPARIVNIS----SPVTVNEGGNVNLLCLAVGR- 159
D G+Y C+ + HQ T++ L+V P++ + ++ +V G +V +C A +
Sbjct: 1740 DAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKS 1799
Query: 160 PEPTVTWRQLRDG-----FTSEGEILEISDIQRGQAGEYECVTHN--------------- 199
P T+ W +L +G IL I ++Q AG Y C N
Sbjct: 1800 PAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA 1859
Query: 200 -GVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS 258
G SAP V +PP +T G+ A RC A P +W +
Sbjct: 1860 SGTLSAP------VVSIHPPQLT------VQPGQLAEFRCSATGSPTPTLEW-------T 1900
Query: 259 SGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
G L + + +L V Y CRA + G A
Sbjct: 1901 GGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVA 1944
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/232 (21%), Positives = 80/232 (34%), Gaps = 27/232 (11%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVH-----VPARIVNISSPVTVNE---------GGNVN 151
D G Y C + L+V +PA + S TV G +V
Sbjct: 3359 DSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVE 3418
Query: 152 LLCLAVGRPEPTVTW----RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
C + W QL G + + +L I ++ + G Y C H A S
Sbjct: 3419 FHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQAS 3478
Query: 208 RRVLVTVNYPPTITDVTSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
++++ I TS +T + G A C A+ P W K L G +
Sbjct: 3479 AQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQ--- 3535
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPR 318
+ ++ A+V G Y C A N G + + + LL + S P+
Sbjct: 3536 -----SGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQ 3582
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/281 (21%), Positives = 97/281 (34%), Gaps = 30/281 (10%)
Query: 44 VCEGDNATLSCFIDEHV-TRVAWLNRSNILYAGNDRWTSDPRVRLLINTPE---EFSILI 99
V EG L C + +V W R L A + P +RL +P E+S +
Sbjct: 2838 VAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQ--VHGPLLRLNQVSPADSGEYSCQV 2895
Query: 100 TEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGR 159
T G G S +P + + I +S V EG ++L C+ G+
Sbjct: 2896 T----GSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQ 2951
Query: 160 PEPTVTWRQ----LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVN---------SAPD 206
VTW + L + G L + + +GEY C +G + P
Sbjct: 2952 AHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPP 3011
Query: 207 SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAM-AVPPADFQWYKDDRLLSSGTAEGL 265
S + P D S+ G+ A +C P +W ++ L
Sbjct: 3012 SEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELED------ 3065
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V S++ ++G Y C A+N G + + + L
Sbjct: 3066 NVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 3106
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/221 (25%), Positives = 78/221 (35%), Gaps = 33/221 (14%)
Query: 120 PYTTQVYLIVHV-PARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW-----RQLRDGF 173
P T Q L+V V PAR + V +GG+ +L C G P W R + G
Sbjct: 1670 PETNQAPLVVEVHPARSI-------VPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGT 1722
Query: 174 TS--EGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPP-----TITDVTSA 226
+G L +Q AG Y C N ++ + SR L+ P T+ + S
Sbjct: 1723 QQRHQGSELHFPSVQPSDAGVYICTCRN-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQ 1781
Query: 227 RTALGRAALLRCEAMAVPPA-DFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARH 285
G C A + PA W + L +G L + +L NV
Sbjct: 1782 SVRPGADVTFICTAKSKSPAYTLVWTR----LHNGK---LPTRAMDFNGILTIRNVQLSD 1834
Query: 286 YGNYTCRAANRLGASSASMRLLRPGSLENSAP----RPPGL 322
G Y C +N + L S SAP PP L
Sbjct: 1835 AGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQL 1875
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 11/125 (8%)
Query: 188 GQAGEY--ECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTAL--GRAALLRCEAMAV 243
G G+Y +C N + + L N P + +V AR+ + G + LRC+
Sbjct: 1644 GYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGS 1703
Query: 244 PPADFQWYKDD-RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
PP F W ++D R + SGT Q S L F +V G Y C N ++++
Sbjct: 1704 PPHYFYWSREDGRPVPSGT------QQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTS 1757
Query: 303 SMRLL 307
LL
Sbjct: 1758 RAELL 1762
Score = 34.7 bits (78), Expect = 0.12
Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 13/89 (14%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWR--------QLRDGFTSEG--EILEISDIQRGQAG 191
+ + G V C+A+G P P + WR R TSEG L I D++ G
Sbjct: 416 IQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQG 475
Query: 192 EYECVTHNG---VNSAPDSRRVLVTVNYP 217
Y C N V PD LV P
Sbjct: 476 AYTCEAMNARGMVFGIPDGVLELVPQRGP 504
Score = 29.6 bits (65), Expect = 4.0
Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 2/74 (2%)
Query: 225 SARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSAR 284
S + + G+ C A+ VP W + + S + V +E R L+ +V
Sbjct: 415 SIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPR--VTVTSEGGRGTLIIRDVKES 472
Query: 285 HYGNYTCRAANRLG 298
G YTC A N G
Sbjct: 473 DQGAYTCEAMNARG 486
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 84.0 bits (206), Expect = 2e-16
Identities = 59/223 (26%), Positives = 89/223 (39%), Gaps = 23/223 (10%)
Query: 99 ITEVGLGDEGLYTCSFQTRH--QPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ +V G EG Y C T H Y+ + L V+V +T+ L C A
Sbjct: 564 LRQVTFGHEGRYQCVI-TNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTTMARLECAA 622
Query: 157 VGRPEPTVTWRQLRDGFTS-------------EGEILEISDIQRGQAGEYECVTHNGVNS 203
G P P + W+ +DG T + ++ I+D++ AG Y C N S
Sbjct: 623 TGHPNPQIAWQ--KDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAGS 680
Query: 204 APDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
+ L + P + + ++G L+C+A PP W+K DR LS
Sbjct: 681 I-SANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERH 739
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
L + +L+ NV A G YTC +N LG A +L
Sbjct: 740 HLTPDNQ----LLVVQNVVAEDAGRYTCEMSNTLGTERAHSQL 778
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/177 (26%), Positives = 73/177 (41%), Gaps = 22/177 (12%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEHVT-RVAWLNRSNILYAGNDRWTSDP--RVRLLINT 91
F + T+ A L C H ++AW D T P R R +
Sbjct: 601 FTKTPHDITIRTTTMARLECAATGHPNPQIAWQK---------DGGTDFPAARERRMHVM 651
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYL-IVHVPARIVNISSPVTVNEGGNV 150
P++ IT+V + D G+Y+C+ Q + L ++ P+ +V + V V+ G V
Sbjct: 652 PDDDVFFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRV-VSVGETV 710
Query: 151 NLLCLAVGRPEPTVTW----RQL----RDGFTSEGEILEISDIQRGQAGEYECVTHN 199
L C A G P P +TW R L R T + ++L + ++ AG Y C N
Sbjct: 711 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 767
Score = 45.4 bits (106), Expect = 7e-05
Identities = 37/132 (28%), Positives = 52/132 (39%), Gaps = 9/132 (6%)
Query: 179 ILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTIT----DVTSARTALGRAA 234
IL + + G G Y+CV N S S + +TVN P+ T D+T T + R
Sbjct: 561 ILHLRQVTFGHEGRYQCVITNHFGST-YSHKARLTVNVLPSFTKTPHDITIRTTTMAR-- 617
Query: 235 LLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAA 294
L C A P W KD A ++ + +V G Y+C A
Sbjct: 618 -LECAATGHPNPQIAWQKDGG-TDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQ 675
Query: 295 NRLGASSASMRL 306
N G+ SA+ L
Sbjct: 676 NSAGSISANATL 687
Score = 30.8 bits (68), Expect = 1.8
Identities = 25/115 (21%), Positives = 41/115 (35%), Gaps = 8/115 (6%)
Query: 194 ECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVP--PADFQWY 251
E + + S P V P IT + +G+ C A + P F W
Sbjct: 472 ESLKGQSIFSVPPESFVCDDFLKPQIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWK 531
Query: 252 KDDRLLSSGTAEGL------KVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS 300
KD+ +L++ E + ++L V+ H G Y C N G++
Sbjct: 532 KDNEVLTNADMENFVHVHAQDGEVMEYTTILHLRQVTFGHEGRYQCVITNHFGST 586
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 82.8 bits (203), Expect = 4e-16
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 57/303 (18%)
Query: 41 NYTVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSIL 98
N TV EG A L+C +D++ T + W N + LY + + D R+ L+ + E SI
Sbjct: 33 NVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRASWHELSIS 92
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPAR--IVNISSPVTVNEGGNVNLLCLA 156
+++V L DEG YTCS T + ++ VP + I SSPV EG + L C
Sbjct: 93 VSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVM--EGDLMQLTCKT 150
Query: 157 VG-RPEPTVTWRQLRDGFTSEGEILEISDIQRGQAGEYEC-------------------- 195
G +P + W F ++ EI ++ ++ A
Sbjct: 151 SGSKPAADIRW------FKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVI 204
Query: 196 --VTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR-TALGRAALLRCEAMAVP-PADFQWY 251
V H +N+ P ++ ++Y P++ + S G+ +L CE+ P P W
Sbjct: 205 CRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLWT 264
Query: 252 KD-------DRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
KD DR++ SG +LF N + G Y C A N +G SSA
Sbjct: 265 KDGGELPDPDRMVVSG-----------RELNILFLNKTDN--GTYRCEATNTIGQSSAEY 311
Query: 305 RLL 307
L+
Sbjct: 312 VLI 314
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 81.6 bits (200), Expect = 9e-16
Identities = 67/278 (24%), Positives = 107/278 (38%), Gaps = 28/278 (10%)
Query: 40 DNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDR---WTSDPRVRLLINTPEEFS 96
+N TV G+ A L+C I V N+ + NDR R+R L N S
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDY-------NLTWQRNDRDVRLAEPARIRTLAN----LS 575
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ + V D G Y C + V+L V P ++ + + G V+++C A
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSA 635
Query: 157 VGRPEPTVTWR--------QLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
G P+P + W R TS+G + I + AG Y C+ N +
Sbjct: 636 TGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF-IKNAAPKDAGIYGCLASNSAGT-DKQN 693
Query: 209 RVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQ 268
L + P + + ALG ++ C+ +PP +W+K D L T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF----LI 749
Query: 269 TERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ +L G+YTC A N G ++ + L
Sbjct: 750 IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITL 787
Score = 81.6 bits (200), Expect = 9e-16
Identities = 68/220 (30%), Positives = 94/220 (42%), Gaps = 16/220 (7%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
+I I L G YTC + V L VH P I S + V + L C
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCE 4010
Query: 156 AVGRPEPTVTWRQLRDGFTSEGEI--------LEISDIQRGQAGEYECVTHNGVNSAPDS 207
A G P P +TW++ + G L+IS R AG Y CV N +A
Sbjct: 4011 ATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTA--L 4068
Query: 208 RRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
++ + V PP I+ + A+ + L CEA +PP D W+KD R + E ++
Sbjct: 4069 GKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI----VESIR 4124
Query: 267 VQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
Q + L A V G+YTC AAN G+SS S +L
Sbjct: 4125 -QRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 79.7 bits (195), Expect = 3e-15
Identities = 61/213 (28%), Positives = 93/213 (43%), Gaps = 19/213 (8%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
S+ I V GD G YTC +T L VHVP RI + TVNE L C+
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCV 4191
Query: 156 AVGRPEPTVTWRQ-------LRDGFTSE--GEILEISDIQRGQAGEYECVTHNGVNSAPD 206
A G P P + W++ L +T+E GE++ + ++ +G Y CV +N + D
Sbjct: 4192 ADGIPTPAINWKKDNVLLANLLGKYTAEPYGELI-LENVVLEDSGFYTCVANNA--AGED 4248
Query: 207 SRRVLVTVNYPPTITDVT-SARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+ V +TV+ PT T++ G L C+A +P W ++ ++ +
Sbjct: 4249 THTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPA------ 4302
Query: 266 KVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
+ S L+ VS G Y C A N +G
Sbjct: 4303 HFDSVNGHSELVIERVSKEDSGTYVCTAENSVG 4335
Score = 79.0 bits (193), Expect = 6e-15
Identities = 71/279 (25%), Positives = 105/279 (37%), Gaps = 30/279 (10%)
Query: 43 TVCEGDNATLSCFIDEHVTRV-AWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITE 101
+V G+ TL C + + W + ++ + R T P S+ ITE
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP----------SGSMKITE 1139
Query: 102 VGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
D G+Y C T V L VHVP +I + V G V++ C A G P
Sbjct: 1140 TRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPL 1199
Query: 162 PTVTWRQLRDGFTSEGE--------ILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVT 213
P +TW + +GE L I AG Y CV N + D + +
Sbjct: 1200 PVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN--IAGTDETEITLH 1257
Query: 214 VNYPPTITDV------TSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKV 267
V PPT+ D+ T + C A P +W + R L +G G+ +
Sbjct: 1258 VQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 268 QTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ T +L+ A+V+ G Y C A N G + L
Sbjct: 1317 LEDGT--LLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Score = 76.3 bits (186), Expect = 4e-14
Identities = 76/286 (26%), Positives = 109/286 (38%), Gaps = 40/286 (13%)
Query: 37 SPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGN-DRWTSDPRVRLLINTPEEF 95
S +YTV E A L C D T + N+L A ++T++P L++
Sbjct: 4173 STEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN---- 4228
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
V L D G YTC T V L VHV + V++N+G + L C
Sbjct: 4229 ------VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCK 4282
Query: 156 AVGRPEPTVTWRQLR-------DGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
A G P P +TW D E++ I + + +G Y C N V
Sbjct: 4283 ATGIPLPKLTWTFNNNIIPAHFDSVNGHSELV-IERVSKEDSGTYVCTAENSVGFVKAIG 4341
Query: 209 RVLVTVNYPPTITDVTSAR--TALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
V V PP + LG A+L CE P QW + +G+
Sbjct: 4342 --FVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNR----------KGVD 4389
Query: 267 VQ-TERTR-----SMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++ + R R S+ ++ V+ G+YTC A N G SM L
Sbjct: 4390 IEISHRIRQLGNGSLAIYGTVN-EDAGDYTCVATNEAGVVERSMSL 4434
Score = 75.5 bits (184), Expect = 6e-14
Identities = 70/284 (24%), Positives = 111/284 (39%), Gaps = 35/284 (12%)
Query: 40 DNYTVCEGDNATLSCFID-EHVTRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSI 97
+ TV +A + C R +W +L + ++ S+ R+ ++NT
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ----- 2934
Query: 98 LITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP-VTVNEGGNVNLLCLA 156
+ D G Y C + L VHVP ++ S +TV ++L C
Sbjct: 2935 ------ITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEV 2988
Query: 157 VGRPEPTVTWRQLRDGFTSE--------GEILEISDIQRGQAGEYECVTHNGVNSAPDSR 208
G P P ++W + G L+I + GEY C+ +N A +S+
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIA---INQAGESK 3045
Query: 209 RVL-VTVNYPPTITDVTSARTAL-----GRAALLRCEAMAVPPADFQWYKDDRLLSSGTA 262
+ +TV PP+I D S ++ G + L CE+ AVPP WYK+ R+++ T
Sbjct: 3046 KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITEST- 3104
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V+ ML G Y CRA N G + L
Sbjct: 3105 ---HVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHL 3145
Score = 74.7 bits (182), Expect = 1e-13
Identities = 78/280 (27%), Positives = 110/280 (39%), Gaps = 31/280 (11%)
Query: 32 SLEFNSPADNYTVCEGDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINT 91
SLE N TV + L C + V + N L +G+ T R ++
Sbjct: 1920 SLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI---- 1975
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVN 151
I I + D G+Y C L VHV I ++ V V V
Sbjct: 1976 -----IDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVR 2030
Query: 152 LLCLAVGRPEPTVTWRQLRDG-----------FTSEGEILEISDIQRGQAGEYECVTHNG 200
L C A G P P++TW L+DG S G IL ++ Q G Y CV
Sbjct: 2031 LECEARGIPAPSLTW--LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCV---A 2085
Query: 201 VNSAPDSRR-VLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS 258
VN+A + +R + + V PP I + + + +A L C++ A+PP W KD L
Sbjct: 2086 VNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL 2145
Query: 259 SGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
GL + RS+L + + G YTC A N G
Sbjct: 2146 K--KPGLSI--SENRSVLKIEDAQVQDTGRYTCEATNVAG 2181
Score = 72.0 bits (175), Expect = 7e-13
Identities = 59/220 (26%), Positives = 92/220 (41%), Gaps = 25/220 (11%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS-SPVTVNEGGNVNLLCL 155
++I + + + GLY C + + + VHVP I + S V + V L C+
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCI 1849
Query: 156 AVGRPEPTVTWRQLRDG-----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204
A G P P++TW L+D S G +L+I+ AG Y CV N
Sbjct: 1850 ANGIPNPSITW--LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGET 1907
Query: 205 PDSRRVLVTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ + + V+ PP++ D + + + L C+A P WYKD+RLLS T
Sbjct: 1908 --QQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST 1965
Query: 262 AEGLKVQTERTRSMLL-FANVSARHYGNYTCRAANRLGAS 300
+ T R ++ + G Y C A N GA+
Sbjct: 1966 S-----MTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Score = 72.0 bits (175), Expect = 7e-13
Identities = 63/225 (28%), Positives = 96/225 (42%), Gaps = 26/225 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV-NISSP--VTVNEGGNVNLLCL 155
+ + + D G Y C + L VH P I+ N SP ++V E +V+L C
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 156 AVGRPEPTVTWRQLRDGFT----------SEGEILEISDIQRGQAGEYECVTHNGVNSAP 205
A G P P++TW +DG+ S G +L + AG+Y CV N +A
Sbjct: 2410 ASGIPLPSITW--FKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN---AAG 2464
Query: 206 DSRRVL-VTVNYPPTITD---VTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
+ R++ ++V PP I + + ++ L CE P + W+KD + L
Sbjct: 2465 EERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
A + + R L NV H G YTC A++ G S S L
Sbjct: 2525 AHHI-ISGGR---FLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 71.2 bits (173), Expect = 1e-12
Identities = 60/216 (27%), Positives = 86/216 (39%), Gaps = 27/216 (12%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP--VTVNEGGNVNLLCLA 156
I+ + D G YTC + + + VHVP I P +TV V L C +
Sbjct: 3586 ISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKS 3645
Query: 157 VGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
P P +TW LR+G S G L+I++ G Y CV N +
Sbjct: 3646 DAVPPPVITW--LRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN--IAGKT 3701
Query: 207 SRRVLVTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
+R ++TVN PP I S L ++ +L C A VP W KD +L+ A
Sbjct: 3702 TREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYS 3761
Query: 266 KVQTERTRSMLLFANVSARHY---GNYTCRAANRLG 298
++ F ++ + H G Y C A N G
Sbjct: 3762 ILENG-------FLHIQSAHVTDTGRYLCMATNAAG 3790
Score = 71.2 bits (173), Expect = 1e-12
Identities = 70/276 (25%), Positives = 101/276 (36%), Gaps = 28/276 (10%)
Query: 43 TVCEGDNATLSCFIDEHVTRV-AWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITE 101
TV TL C D V WL +R + PRVR+L + I
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNG-------ERLQATPRVRILSGGRY---LQINN 3681
Query: 102 VGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPE 161
LGD YTC T + L V+VP I + + + L C+A G P
Sbjct: 3682 ADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPT 3741
Query: 162 PTVTWRQLRDGFTSEGEILEISDIQRG----------QAGEYECVTHNGVNSAPDSRRVL 211
P +TWR +DG G S ++ G G Y C+ N + D RR+
Sbjct: 3742 PRITWR--KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGT--DRRRID 3797
Query: 212 VTVNYPPTIT-DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTE 270
+ V+ PP+I T+ + L CEA +P W K+ LL+ +
Sbjct: 3798 LQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLN--VDQNQNSYRL 3855
Query: 271 RTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
+ L+ + S Y C N G ++ L
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDL 3891
Score = 70.1 bits (170), Expect = 3e-12
Identities = 62/218 (28%), Positives = 83/218 (38%), Gaps = 26/218 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV--NISSPVTVNEGGNVNLLCLA 156
+ + + D G YTC + L V VP IV N V V E +V L C
Sbjct: 2444 LMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEV 2503
Query: 157 VGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
G P P +TW +DG S G L+I+++Q G Y C+ + +
Sbjct: 2504 TGNPVPEITWH--KDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASS--PAGHK 2559
Query: 207 SRRVLVTVNYPPTITDVTS------ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSG 260
SR + V PTI V S L L CEA + PPA W+KD L S
Sbjct: 2560 SRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN 2619
Query: 261 TAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
++ L N + G Y+C A N G
Sbjct: 2620 R----NIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 69.7 bits (169), Expect = 3e-12
Identities = 58/214 (27%), Positives = 81/214 (37%), Gaps = 18/214 (8%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGN-VNLLCLAV 157
I + + D G Y C +L V+VP I V V N V L C A
Sbjct: 3117 IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDAT 3176
Query: 158 GRPEPTVTWRQ----------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPDS 207
G P PT+ W + L S G L+I+ Q +G Y C+ N A
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKA--Q 3234
Query: 208 RRVLVTVNYPPTITDV---TSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEG 264
+ +++ PP++ + LG L C A +P QW KD + ++SG E
Sbjct: 3235 KYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 265 LKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
++V S L G YTC A N G
Sbjct: 3295 IRVSA--NGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 67.4 bits (163), Expect = 2e-11
Identities = 57/219 (26%), Positives = 92/219 (42%), Gaps = 19/219 (8%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG 158
I +V L DEG Y C + Q + V P ++ + + VTV G L CL +
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 159 RPEPTVTW-RQLRDGFTSE--------GEILEISDIQRGQAGEYEC-VTHNGVNSAPDSR 208
+ +TW R RD +E LE+ ++ AGEY C V+ G +SA
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS-- 603
Query: 209 RVLVTVNYPPTITDVTSARTALGRAAL-LRCEAMAVPPADFQWYKDDRLLSSGTAEGLKV 267
V +TV PP +T + ++ G + + + C A P W +D + + ++
Sbjct: 604 -VFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG--SHRYRM 660
Query: 268 QTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
++ T L N + + G Y C A+N G + L
Sbjct: 661 TSDGT---LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696
Score = 67.4 bits (163), Expect = 2e-11
Identities = 69/243 (28%), Positives = 95/243 (39%), Gaps = 27/243 (11%)
Query: 80 TSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNIS 139
TS +V +L P + I + D G YTC + Q + V VP I +
Sbjct: 2819 TSSDKVLIL---PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGAN 2875
Query: 140 SP----VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDI 185
S VTV + + CL+ G P P +W+ +DG F S G IL+I +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQ--KDGQPLLEDDHHKFLSNGRILQILNT 2933
Query: 186 QRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSAR--TALGRAALLRCEAMAV 243
Q G Y CV N SA + + V+ PP++ S + L CE
Sbjct: 2934 QITDIGRYVCVAENTAGSA--KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGF 2991
Query: 244 PPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
PP D W K+++ + T L V RT L G YTC A N+ G S
Sbjct: 2992 PPPDLSWLKNEQPIKLNT-NTLIVPGGRT---LQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 304 MRL 306
L
Sbjct: 3048 FSL 3050
Score = 66.2 bits (160), Expect = 4e-11
Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 23/243 (9%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ +T + D G YTC + L V+VP I+ V+V V LLC +
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQS 2127
Query: 157 VGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
P PT+TW L+DG + +L+I D Q G Y C N
Sbjct: 2128 DAIPPPTLTW--LKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 207 SRRVLVTVNYPPTI---TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAE 263
+ V + V PP I ++T G L CE+ +PP + W K + + +
Sbjct: 2186 NYNVNIWV--PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMG 2243
Query: 264 GLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL---LRPGSLENSAPRPP 320
+++ + + + A S Y+C A+N G + L +RP ++ NS P
Sbjct: 2244 RVRILSGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQVYIRP-TITNSGSHPT 2300
Query: 321 GLL 323
++
Sbjct: 2301 EII 2303
Score = 64.3 bits (155), Expect = 1e-10
Identities = 62/224 (27%), Positives = 78/224 (34%), Gaps = 32/224 (14%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSP-----VTVNEGGNVNLL 153
IT V + G YTC + + L V V I + S VTV +L+
Sbjct: 2537 ITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLV 2596
Query: 154 CLAVGRPEPTVTWRQLRDGFTSE----------GEILEISDIQRGQAGEYECVTHNGVNS 203
C A P T+TW +DG E G L+I + Q AG Y CV N
Sbjct: 2597 CEAYSYPPATITW--FKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 204 APDSRRVLVTVNYPPTIT---------DVTSARTALGRAALLRCEAMAVPPADFQWYKDD 254
V V + PP I + + L CEA A+P A WYKD
Sbjct: 2655 MIKHYEVKVYI--PPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDG 2712
Query: 255 RLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
+ L S V L G YTC A+N G
Sbjct: 2713 QPLKSDD----HVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/217 (24%), Positives = 85/217 (39%), Gaps = 23/217 (10%)
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNI--SSPVTVNEGGNVNLLC 154
I I + D +YTC R L V P + N + +TV +G + ++ C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 155 LAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSA 204
+ G P P++ W LRDG ++ G +L++ + +G+Y C+ N
Sbjct: 3458 ITDGTPAPSMAW--LRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEV 3515
Query: 205 PDSRRVLVTVNYPPTIT---DVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGT 261
S+ ++ V PP I + + L C A +P W KD R L
Sbjct: 3516 --SKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD 3573
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
+VQT +L + G YTC A++ G
Sbjct: 3574 ----QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAG 3606
Score = 63.9 bits (154), Expect = 2e-10
Identities = 56/180 (31%), Positives = 84/180 (46%), Gaps = 21/180 (11%)
Query: 150 VNLLCLAVGRPEPTVTWRQ------LRDGFTS--EGEILEISDIQRGQAGEYECVTHNGV 201
+ L C G P PT+ W + RDGF G L I+ Q G Y C+
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMA---A 1808
Query: 202 NSAPDSRRVL-VTVNYPPTI--TDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLS 258
N+A D ++ VTV+ PPTI + ++ + L+C A +P W KDD+ ++
Sbjct: 1809 NTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVN 1868
Query: 259 SGTAEG-LKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRL--LRPGSLENS 315
TA+G LK+Q+ + +L A G YTC A N G + ++L P SLE++
Sbjct: 1869 --TAQGNLKIQS--SGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Score = 63.5 bits (153), Expect = 2e-10
Identities = 65/236 (27%), Positives = 93/236 (39%), Gaps = 36/236 (15%)
Query: 84 RVRLLINTPEEFSILITEVGLGDEGLYTCSFQ----TRHQPYTTQVYLIVHVPARIVNIS 139
RVR+L + + I I E D LY+C T + Y QVY + I N
Sbjct: 2244 RVRIL-SGGRQLQISIAEKS--DAALYSCVASNVAGTAKKEYNLQVY----IRPTITNSG 2296
Query: 140 SPVT---VNEGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQ 186
S T V G +++L C G P PTVTW ++DG EG IL++ +I
Sbjct: 2297 SHPTEIIVTRGKSISLECEVQGIPPPTVTW--MKDGHPLIKAKGVEILDEGHILQLKNIH 2354
Query: 187 RGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI----TDVTSARTALGRAALLRCEAMA 242
G Y CV N ++ ++V+ PP+I + + L CEA
Sbjct: 2355 VSDTGRYVCVAVNVAGMT--DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASG 2412
Query: 243 VPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
+P W+KD +S + V+ ML + G YTC N G
Sbjct: 2413 IPLPSITWFKDGWPVSLSNS----VRILSGGRMLRLMQTTMEDAGQYTCVVRNAAG 2464
Score = 62.4 bits (150), Expect = 6e-10
Identities = 62/227 (27%), Positives = 82/227 (36%), Gaps = 29/227 (12%)
Query: 96 SILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCL 155
S++I + D Y C+ V L V VP I + + V + + C
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCT 3919
Query: 156 AVGRPEPTVTWRQ-------LRDGF--TSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
A G P P++ W + DG+ S G I EI Q AG Y CV N SA
Sbjct: 3920 ASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI-EILATQLNHAGRYTCVARNAAGSA-- 3976
Query: 207 SRRVLVTVNYPPTITDVTS-ARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGL 265
R V + V+ PP I S L LL CEA P W K EG+
Sbjct: 3977 HRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQK----------EGI 4026
Query: 266 KVQTERTRSMLL------FANVSARHYGNYTCRAANRLGASSASMRL 306
V T +L + G Y C A N G + ++L
Sbjct: 4027 NVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKL 4073
Score = 61.6 bits (148), Expect = 9e-10
Identities = 64/250 (25%), Positives = 95/250 (38%), Gaps = 25/250 (10%)
Query: 72 LYAGNDRWTSDPRVRLLINTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVH 130
L+ G + +P + +L E+ ++L I V D G Y C + L VH
Sbjct: 1301 LHNGRELTGREPGISIL----EDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH 1356
Query: 131 VPARIVNISSPVTVNEGGN--VNLLCLAVGRPEPTVTWR----QLRDGFT----SEGEIL 180
VP I + V+ N NL C G P P + W Q+ + T + G+IL
Sbjct: 1357 VPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKIL 1416
Query: 181 EISDIQRGQAGEYECVTHNGVNSAPDSRRVL-VTVNYPPTITDVT---SARTALGRAALL 236
++ AG Y C +N A S++ + V PPTI L R L
Sbjct: 1417 KLFRATPEDAGRYSC---KAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVAL 1473
Query: 237 RCEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANR 296
C+ P D W+KD + L G V+ +L N G Y C +N
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP---NVELLDRGQVLHLKNARRNDKGRYQCTVSNA 1530
Query: 297 LGASSASMRL 306
G + ++L
Sbjct: 1531 AGKQAKDIKL 1540
Score = 61.2 bits (147), Expect = 1e-09
Identities = 62/216 (28%), Positives = 87/216 (40%), Gaps = 24/216 (11%)
Query: 99 ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV-NISSPVT--VNEGGNVNLLCL 155
I + D YTC ++ V+VP I N+++P+ V ++ L C
Sbjct: 1605 IPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECK 1664
Query: 156 AVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVNSAP 205
A G P P +TW L+DG + G+ LEI Q G+Y CV +
Sbjct: 1665 AAGNPSPILTW--LKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKE 1722
Query: 206 DSRRVLVTVNYPPTIT--DVTSARTALGRAAL-LRCEAMAVPPADFQWYKDDRLLSSGTA 262
V V V PP I D TS + L L C PP W KD +L+
Sbjct: 1723 IKYEVDVLV--PPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDE--R 1778
Query: 263 EGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLG 298
+G K+ + ++ A VS + G Y C AAN G
Sbjct: 1779 DGFKILLNGRKLVIAQAQVS--NTGLYRCMAANTAG 1812
Score = 59.7 bits (143), Expect = 4e-09
Identities = 56/210 (26%), Positives = 81/210 (38%), Gaps = 19/210 (9%)
Query: 106 DEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVT 165
D G YTC T ++ L V P + + V++ G NV L C G PEPT+
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIK 825
Query: 166 WRQLRDG--FTSEGEILEISDIQRG----------QAGEYECVTHNGVNSAPDSRRVLVT 213
WR+L + F+ + IS ++ G G Y C N V VT
Sbjct: 826 WRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Query: 214 VNYPPTITDVTSARTAL-GRAALLRCEAMAVPP-ADFQWYKDDRLLSSGTAEGLKVQTER 271
P I S + G+ L C +A P + +W K+ +L T R
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN-----PYITVR 940
Query: 272 TRSMLLFANVSARHYGNYTCRAANRLGASS 301
+ L V + G YTC A+N G ++
Sbjct: 941 SDGSLHIERVQLQDGGEYTCVASNVAGTNN 970
Score = 59.3 bits (142), Expect = 5e-09
Identities = 69/285 (24%), Positives = 102/285 (35%), Gaps = 63/285 (22%)
Query: 44 VCEGDNATLSCFIDEHVTRVAWLNRSNILYAGND----RWTSDPRVRL---LINTPEEFS 96
V EG TL C L AGN RW + + L I + S
Sbjct: 901 VIEGQQLTLPC----------------TLLAGNPIPERRWIKNSAMLLQNPYITVRSDGS 944
Query: 97 ILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLA 156
+ I V L D G YTC ++VHV I + ++ EG V L C A
Sbjct: 945 LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKA 1004
Query: 157 VGRPEPTVTWRQLRDGFTSEGEILEISDIQRG---------------QAGEYECVTHNGV 201
G P+P+V W + +GE++ S + ++GEY C N
Sbjct: 1005 SGNPKPSVIW-------SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTA 1057
Query: 202 NSAPDSRRVLVTVNYPPTI---------TDVTSARTALGRAALLRCEAMAVPPADFQWYK 252
A R+V +TV P + G L CE ++PP W K
Sbjct: 1058 GYA--KRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK 1115
Query: 253 DDRLLSSGT-------AEGLKVQTERTRSMLLFANVSARHYGNYT 290
+ +L+S + + +K+ RT ++ V+ GN T
Sbjct: 1116 ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVT 1160
Score = 53.1 bits (126), Expect = 3e-07
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 17/176 (9%)
Query: 47 GDNATLSCFIDEHVTRVAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGD 106
G NA L+C + T NR + D + I S+ I D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGV----------DIEISHRIRQLGNGSLAIYGTVNED 4413
Query: 107 EGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTW 166
G YTC + L + P I +N GG + L C A G P+PT+TW
Sbjct: 4414 AGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITW 4473
Query: 167 RQLRDGFTSEGEI-------LEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVN 215
+ + + + L I+D Q+ E+ECV N + S V+V V+
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVH 4529
Score = 52.0 bits (123), Expect = 7e-07
Identities = 54/241 (22%), Positives = 93/241 (38%), Gaps = 29/241 (12%)
Query: 75 GNDRWTSDPRVRLLINTPEEFSIL-ITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPA 133
G + DP V LL + +L + D+G Y C+ + L +++P
Sbjct: 1491 GKPLFLGDPNVELL----DRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Query: 134 RIV--NISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEGEILE 181
I N+++ ++V + L C G P P +TW +DG + +G+ L
Sbjct: 1547 SIKGGNVTTDISVLINSLIKLECETRGLPMPAITW--YKDGQPIMSSSQALYIDKGQYLH 1604
Query: 182 ISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTI----TDVTSARTALGRAALLR 237
I Q + Y C N +A S V V V PP I + + + + L
Sbjct: 1605 IPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV--PPMIEGNLATPLNKQVVIAHSLTLE 1662
Query: 238 CEAMAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRL 297
C+A P W KD + + + ++++ + ++ A R G Y C A +
Sbjct: 1663 CKAAGNPSPILTWLKDGVPVKAN--DNIRIEAGGKKLEIMSAQEIDR--GQYICVATSVA 1718
Query: 298 G 298
G
Sbjct: 1719 G 1719
Score = 49.7 bits (117), Expect = 4e-06
Identities = 46/191 (24%), Positives = 66/191 (34%), Gaps = 29/191 (15%)
Query: 142 VTVNEGGNVNLLCLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAG 191
V + + L C A P +++W +DG + G L+I + Q G
Sbjct: 2684 VKIKVNNTLTLECEAYAIPSASLSW--YKDGQPLKSDDHVNIAANGHTLQIKEAQISDTG 2741
Query: 192 EYECVTHN-----------GVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEA 240
Y CV N + P +++ N T + + + L CE
Sbjct: 2742 RYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCET 2801
Query: 241 MAVPPADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGAS 300
A PP WYKD L+S KV +L G YTC A N G
Sbjct: 2802 NAAPPPTLTWYKDGHPLTSSD----KVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857
Query: 301 SA--SMRLLRP 309
S +R+L P
Sbjct: 2858 SLQYDVRVLVP 2868
Score = 49.3 bits (116), Expect = 5e-06
Identities = 70/298 (23%), Positives = 113/298 (37%), Gaps = 38/298 (12%)
Query: 38 PADNYTVCEGDNATLSCFIDEHVTR-VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFS 96
P+D +V G+N L C + T + WL + +G R+R+ N +
Sbjct: 3253 PSD-VSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE-----RIRVSANGS---T 3303
Query: 97 ILITEVGLGDEGLYTCSFQT----RHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNL 152
+ I D G YTC + + VY+ + +T+ + ++N+
Sbjct: 3304 LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT-SINI 3362
Query: 153 LCLAVGRPEPTVTWRQLRDG----------FTSEGEILEISDIQRGQAGEYECVTHNGVN 202
C A G P P + W L++G + G+++ I Q Y CV N
Sbjct: 3363 ECRATGTPPPQINW--LKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN--R 3418
Query: 203 SAPDSRRVLVTVNYPPTITDV--TSARTAL-GRAALLRCEAMAVPPADFQWYKDDRLLSS 259
+ D++ + V PP + + T T L G + + C P W +D + L
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL-- 3476
Query: 260 GTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS--MRLLRPGSLENS 315
G L V T LL A G YTC A+N G S +++L P + S
Sbjct: 3477 GLDAHLTVSTHGMVLQLLKA--ETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGS 3532
>gi|4758822 nephrin precursor [Homo sapiens]
Length = 1241
Score = 81.3 bits (199), Expect = 1e-15
Identities = 80/270 (29%), Positives = 117/270 (43%), Gaps = 37/270 (13%)
Query: 83 PRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPV 142
PR R+L + ++ + V D+GLY Q ++ L VH I + P
Sbjct: 694 PRHRILSSG----ALHLWNVTRADDGLYQLHCQNSEGTAEARLRLDVHYAPTIRALQDPT 749
Query: 143 TVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSEGEIL-EISDIQRG------------- 188
VN GG+V+++C P + R G E + L ++ I RG
Sbjct: 750 EVNVGGSVDIVCTVDANPILPGMFNWERLGEDEEDQSLDDMEKISRGPTGRLRIHHAKLA 809
Query: 189 QAGEYECVTHNGVNSAPDSRRVL-------VTVNYPPTITDVTSARTALGRAALLRCEAM 241
QAG Y+C+ NGV AP +RR+L V +P +T V +A + +A L C A
Sbjct: 810 QAGAYQCIVDNGV--APPARRLLRLVVRFAPQVEHPTPLTKVAAAGDSTS-SATLHCRAR 866
Query: 242 AVPPADFQWYKDD---RLLSSGTAEGLKVQTERTRSMLLFANVS-ARHYGNYTCRAANRL 297
VP F W K+ L E Q S+L ANVS A+ Y +TC A N L
Sbjct: 867 GVPNIVFTWTKNGVPLDLQDPRYTEHTYHQGGVHSSLLTIANVSAAQDYALFTCTATNAL 926
Query: 298 GASSASMRLLRPGSLENSAPRPPGLLALLS 327
G+ +++L + S P PP L ++S
Sbjct: 927 GSDQTNIQL-----VSISRPDPPSGLKVVS 951
Score = 42.0 bits (97), Expect = 8e-04
Identities = 75/325 (23%), Positives = 129/325 (39%), Gaps = 45/325 (13%)
Query: 16 AALAGLAVISRGLLSQSLEFNSPA------DNYTVCEGDNATLSCFIDEHVTRVAWLNRS 69
A+L L +++ GL ++ + P +N TV EG + L C + + V W +
Sbjct: 9 ASLLLLGLLTEGLAQLAIPASVPRGFWALPENLTVVEGASVELRCGVSTPGSAVQWA-KD 67
Query: 70 NILYAGNDRWTSDPRVRLLINTPE-EFSILITEVGLGDEGLYTCSF---QTRHQPYTTQV 125
+L + R PR RL + EF + I L D+ Y C + + + +V
Sbjct: 68 GLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPELVSPRV 127
Query: 126 YLIVHVPARIVNIS----SPVTVNEGGNVNLLCLA-VGRPEPTVTWRQLRDGFTSEGEIL 180
L + VP +++ ++ + VT G + C++ +P P +T L G T
Sbjct: 128 ILSILVPPKLLLLTPEAGTMVTWVAGQEYVVNCVSGDAKPAPDIT--ILLSGQTISDISA 185
Query: 181 EISDIQRGQAGEYECVTHNGVNSAPDSRRVLV----------------TVNY-----PPT 219
+++ + + E S+ D+R++LV TVN PP
Sbjct: 186 NVNEGSQQKLFTVEATARVTPRSS-DNRQLLVCEASSPALEAPIKASFTVNVLFPPGPPV 244
Query: 220 I--TDVTSARTALGRAALLRCEAMAVPP-ADFQWYKDDRLLSSGTAEGLKVQTERTRSML 276
I + G++ L C A P A QW K+ + +S TA G + RS+L
Sbjct: 245 IEWPGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVS--TAWGTEHTQAVARSVL 302
Query: 277 LFANVSARHYGNYTCRAANRLGASS 301
+ H +C A N + A +
Sbjct: 303 VMTVRPEDHGAQLSCEAHNSVSAGT 327
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 81.3 bits (199), Expect = 1e-15
Identities = 74/281 (26%), Positives = 113/281 (40%), Gaps = 30/281 (10%)
Query: 43 TVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSILIT 100
TV G L C + +H + + W N + LY G R D R++L+ +TP E SI I+
Sbjct: 39 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 98
Query: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG-R 159
V L DEG YTCS T + ++ +P + + ++ E L C + G +
Sbjct: 99 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 158
Query: 160 PEPTVTWRQLRDGFTSE---------GEILEISDIQRGQAGEYE-------CVTHNGVNS 203
P +TWR+ E G+ +S Q + V H +
Sbjct: 159 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 218
Query: 204 APDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVP-PADFQWYKDDRLLSSGT 261
A S + V Y PT + G+ LL CE P P + W K+ G+
Sbjct: 219 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE------GS 272
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
LK+ E S L+F ++ G Y C A + +G+ A
Sbjct: 273 VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKA 310
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 81.3 bits (199), Expect = 1e-15
Identities = 74/281 (26%), Positives = 113/281 (40%), Gaps = 30/281 (10%)
Query: 43 TVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSILIT 100
TV G L C + +H + + W N + LY G R D R++L+ +TP E SI I+
Sbjct: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
Query: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG-R 159
V L DEG YTCS T + ++ +P + + ++ E L C + G +
Sbjct: 133 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 192
Query: 160 PEPTVTWRQLRDGFTSE---------GEILEISDIQRGQAGEYE-------CVTHNGVNS 203
P +TWR+ E G+ +S Q + V H +
Sbjct: 193 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 252
Query: 204 APDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVP-PADFQWYKDDRLLSSGT 261
A S + V Y PT + G+ LL CE P P + W K+ G+
Sbjct: 253 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE------GS 306
Query: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
LK+ E S L+F ++ G Y C A + +G+ A
Sbjct: 307 VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKA 344
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 77.4 bits (189), Expect = 2e-14
Identities = 57/225 (25%), Positives = 82/225 (36%), Gaps = 27/225 (12%)
Query: 99 ITEVGLGDEGLYTCSFQTRH-QPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAV 157
+ EV EG Y C Y+ + L V++ +T+ G L C AV
Sbjct: 568 LREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAV 627
Query: 158 GRPEPTVTW-----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
G P P + W R+ R E ++ I D++ G Y C N S
Sbjct: 628 GHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI-S 686
Query: 207 SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+ L + P + + G A+L+C A PP W KDD L
Sbjct: 687 ANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--------- 737
Query: 267 VQTER-----TRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V TER +L+ + G YTC +N LG ++RL
Sbjct: 738 VVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRL 782
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/182 (24%), Positives = 69/182 (37%), Gaps = 23/182 (12%)
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDGF--------------TSEGEILEISDIQR---- 187
+G N++ +C A + +T+ +D GE++E + I R
Sbjct: 512 KGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREV 571
Query: 188 --GQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSART-ALGRAALLRCEAMAVP 244
G+Y+CV N S+ S + +TVN P+ T T G A L C A+ P
Sbjct: 572 EFASEGKYQCVISNHFGSS-YSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHP 630
Query: 245 PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
W KD A ++ + +V G Y+C A N G+ SA+
Sbjct: 631 APQIAWQKDGG-TDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANA 689
Query: 305 RL 306
L
Sbjct: 690 TL 691
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/189 (24%), Positives = 72/189 (38%), Gaps = 20/189 (10%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEH-VTRVAWLNRSNILYAGNDRWTSDP--RVRLLINT 91
F + T+ G A L C H ++AW D T P R R +
Sbjct: 605 FTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQK---------DGGTDFPAARERRMHVM 655
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVN 151
PE+ I +V + D G+Y+C+ Q + L V + TV +G
Sbjct: 656 PEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAV 715
Query: 152 LLCLAVGRPEPTVTWRQ--------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
L C+A G P P + W + R F + ++L I D AG+Y C N + +
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGT 775
Query: 204 APDSRRVLV 212
+ R+ V
Sbjct: 776 ERGNVRLSV 784
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 77.4 bits (189), Expect = 2e-14
Identities = 57/225 (25%), Positives = 82/225 (36%), Gaps = 27/225 (12%)
Query: 99 ITEVGLGDEGLYTCSFQTRH-QPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAV 157
+ EV EG Y C Y+ + L V++ +T+ G L C AV
Sbjct: 508 LREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAV 567
Query: 158 GRPEPTVTW-----------RQLRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNSAPD 206
G P P + W R+ R E ++ I D++ G Y C N S
Sbjct: 568 GHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSI-S 626
Query: 207 SRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQWYKDDRLLSSGTAEGLK 266
+ L + P + + G A+L+C A PP W KDD L
Sbjct: 627 ANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPL--------- 677
Query: 267 VQTER-----TRSMLLFANVSARHYGNYTCRAANRLGASSASMRL 306
V TER +L+ + G YTC +N LG ++RL
Sbjct: 678 VVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRL 722
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/182 (24%), Positives = 69/182 (37%), Gaps = 23/182 (12%)
Query: 146 EGGNVNLLCLAVGRPEPTVTWRQLRDGF--------------TSEGEILEISDIQR---- 187
+G N++ +C A + +T+ +D GE++E + I R
Sbjct: 452 KGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREV 511
Query: 188 --GQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSART-ALGRAALLRCEAMAVP 244
G+Y+CV N S+ S + +TVN P+ T T G A L C A+ P
Sbjct: 512 EFASEGKYQCVISNHFGSS-YSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHP 570
Query: 245 PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
W KD A ++ + +V G Y+C A N G+ SA+
Sbjct: 571 APQIAWQKDGG-TDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANA 629
Query: 305 RL 306
L
Sbjct: 630 TL 631
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/189 (24%), Positives = 72/189 (38%), Gaps = 20/189 (10%)
Query: 35 FNSPADNYTVCEGDNATLSCFIDEH-VTRVAWLNRSNILYAGNDRWTSDP--RVRLLINT 91
F + T+ G A L C H ++AW D T P R R +
Sbjct: 545 FTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQK---------DGGTDFPAARERRMHVM 595
Query: 92 PEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVN 151
PE+ I +V + D G+Y+C+ Q + L V + TV +G
Sbjct: 596 PEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAV 655
Query: 152 LLCLAVGRPEPTVTWRQ--------LRDGFTSEGEILEISDIQRGQAGEYECVTHNGVNS 203
L C+A G P P + W + R F + ++L I D AG+Y C N + +
Sbjct: 656 LQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGT 715
Query: 204 APDSRRVLV 212
+ R+ V
Sbjct: 716 ERGNVRLSV 724
>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
Length = 956
Score = 77.0 bits (188), Expect = 2e-14
Identities = 51/172 (29%), Positives = 77/172 (44%), Gaps = 19/172 (11%)
Query: 143 TVNEGGNVNLLCLAVGRPEPTVTWRQLRDGFTSE-------GEILEISDIQRGQAGEYEC 195
T+ EG + L CL G P P + W + + E L I++IQR Q G Y C
Sbjct: 51 TIREGETLELTCLVTGHPRPQIRWTKTAGSASDRFQDSSVFNETLRITNIQRHQGGRYYC 110
Query: 196 VTHNGVNSAPDSRRVLVTVNY--PPTITDVTSARTA-----LGRAALLRCEAMAVPPADF 248
NG+ S P + + V V Y P +T S A R LRC A + PP +
Sbjct: 111 KAENGLGS-PAIKSIRVDVYYLDDPVVTVHQSIGEAKEQFYYERTVFLRCVANSNPPVRY 169
Query: 249 QWYKDDRLLSSGTAEGLKVQ----TERTRSMLLFANVSARHYGNYTCRAANR 296
W + +L G+ +G+++ T+ +L N+ + Y NY+C A+ R
Sbjct: 170 SWRRGQEVLLQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYSCIASVR 221
Score = 68.2 bits (165), Expect = 1e-11
Identities = 57/235 (24%), Positives = 97/235 (41%), Gaps = 29/235 (12%)
Query: 91 TPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIV--NIS-----SPVT 143
+P ++ I ++ D G YTC + + + + V++ + V N++ SP+
Sbjct: 396 SPGTTNLDIIDLKFTDFGTYTCVASLKGGGIS-DISIDVNISSSTVPPNLTVPQEKSPLV 454
Query: 144 VNEGGNVNLLCLAVGRPEPTVTWRQ------LRDG---FTSEGEILEISDIQRGQAGEYE 194
EG + L C G+P+P + W + + DG S L I ++ R +G Y
Sbjct: 455 TREGDTIELQCQVTGKPKPIILWSRADKEVAMPDGSMQMESYDGTLRIVNVSREMSGMYR 514
Query: 195 CVT--HNGVNSAPDSRRVLVTVNYPPTITDV-TSARTALGRAALLRCEAMAVPP---ADF 248
C T +NG N P V + V YPP + R R+ + C + P +
Sbjct: 515 CQTSQYNGFNVKPREALVQLIVQYPPAVEPAFLEIRQGQDRSVTMSCRVLRAYPIRVLTY 574
Query: 249 QWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSAS 303
+W ++LL +G + + +S+ S +YG Y C N GA S
Sbjct: 575 EWRLGNKLLRTGQFDSQEYTEYAVKSL------SNENYGVYNCSIINEAGAGRCS 623
Score = 56.2 bits (134), Expect = 4e-08
Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 24/184 (13%)
Query: 138 ISSPVTVNEGGNVNLLCLAV-GRPEPTVTWRQ----LRDGFTSEGEILEISDIQRGQAGE 192
+ P+ VN G + L+C+ G P P++TW + L + G L I I AG
Sbjct: 248 VDDPIVVNPGEAITLVCVTTGGEPAPSLTWVRSFGTLPEKTVLNGGTLTIPAITSDDAGT 307
Query: 193 YECVTHNGV-NSAPDSRRVLVT--------VNYPPTITDVTSARTALGRAALLRCEAMAV 243
Y C+ +N V N A S ++V + P D +GR + C+ AV
Sbjct: 308 YSCIANNNVGNPAKKSTNIIVRALKKGRFWITPDPYHKD---DNIQIGREVKISCQVEAV 364
Query: 244 PPAD--FQWYKDDRLLSSGTAEGLKVQTERTRS----MLLFANVSARHYGNYTCRAANRL 297
P + F W+K+ R L S + + QT+ S L ++ +G YTC A+ +
Sbjct: 365 PSEELTFSWFKNGRPLRS-SERMVITQTDPDVSPGTTNLDIIDLKFTDFGTYTCVASLKG 423
Query: 298 GASS 301
G S
Sbjct: 424 GGIS 427
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,018,382
Number of Sequences: 37866
Number of extensions: 592732
Number of successful extensions: 4762
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 1842
Number of HSP's gapped (non-prelim): 1718
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.