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Search of human proteins with 11056046
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 876 0.0
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 790 0.0
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 387 e-107
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 274 1e-73
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 271 1e-72
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 227 1e-59
gi|51593098 class-I MHC-restricted T cell associated molecule [H... 95 1e-19
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 94 2e-19
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 94 2e-19
gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens] 94 3e-19
gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens] 94 3e-19
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 85 1e-16
gi|166295173 kin of IRRE like [Homo sapiens] 84 2e-16
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 83 6e-16
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 82 9e-16
gi|157819143 IgLON family member 5 [Homo sapiens] 81 2e-15
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 81 2e-15
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 80 4e-15
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 80 4e-15
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 80 5e-15
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 78 1e-14
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 77 4e-14
gi|68163411 activated leukocyte cell adhesion molecule [Homo sap... 75 9e-14
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 74 2e-13
gi|45594240 limbic system-associated membrane protein [Homo sapi... 73 4e-13
gi|110349719 titin isoform N2-A [Homo sapiens] 73 6e-13
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 72 7e-13
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 72 7e-13
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens] 72 7e-13
gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens] 72 7e-13
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 876 bits (2264), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML 60
MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML
Sbjct: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML 60
Query: 61 ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 120
ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV
Sbjct: 61 ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 120
Query: 121 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 180
TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD
Sbjct: 121 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 180
Query: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS
Sbjct: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
Query: 241 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 300
IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL
Sbjct: 241 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 300
Query: 301 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 360
WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS
Sbjct: 301 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 360
Query: 361 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 420
STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG
Sbjct: 361 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 420
Query: 421 QSGGDDKKEYFI 432
QSGGDDKKEYFI
Sbjct: 421 QSGGDDKKEYFI 432
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 790 bits (2041), Expect = 0.0
Identities = 398/432 (92%), Positives = 398/432 (92%), Gaps = 34/432 (7%)
Query: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDGYWQEQDLELGTLAPLDEAISSTVWSSPDML 60
MGAPAASLLLLLLLFACCWAPGGANLSQD
Sbjct: 1 MGAPAASLLLLLLLFACCWAPGGANLSQD------------------------------- 29
Query: 61 ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 120
DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV
Sbjct: 30 ---DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 86
Query: 121 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 180
TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD
Sbjct: 87 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 146
Query: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS
Sbjct: 147 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 206
Query: 241 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 300
IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL
Sbjct: 207 IVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYL 266
Query: 301 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 360
WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS
Sbjct: 267 WEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 326
Query: 361 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 420
STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG
Sbjct: 327 STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGG 386
Query: 421 QSGGDDKKEYFI 432
QSGGDDKKEYFI
Sbjct: 387 QSGGDDKKEYFI 398
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 387 bits (993), Expect = e-107
Identities = 197/414 (47%), Positives = 266/414 (64%), Gaps = 43/414 (10%)
Query: 62 SQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVT 121
SQ P T + TVV GGT +L C+V ++++SLQWSNPAQQTLYF +K+ALRDNRI+LV
Sbjct: 24 SQGQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVR 83
Query: 122 STPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDT 181
++ HELSIS+S+V+L+DEG+YTCS+FTMPV+T+K+ +TVLG+P+KP I+G+ S + E D
Sbjct: 84 ASWHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDL 143
Query: 182 ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASI 241
L C++SGSKPAA + W K D+E+ +ED N KTFTVSS++ F+V R DDG ++
Sbjct: 144 MQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAV 203
Query: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLW 301
+C V+HESL + Q +E+ YTP+ I P P P+EGQ L+L CE +G P+P+ LW
Sbjct: 204 ICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQEGQPLILTCESKGKPLPEPVLW 263
Query: 302 EKEGSV---PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL---------- 348
K+G P + L FLNK+D+GTY C AT+ +G A Y L
Sbjct: 264 TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTLL 323
Query: 349 ------------------------------NVNDPSPVPSSSSTYHAIIGGIVAFIVFLL 378
++ DP+ + + HA+IGGIVA +VF+
Sbjct: 324 PTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFVT 383
Query: 379 LIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 432
L + LG YL RHKGTYLT+EAKG++DAPDADTAIINAEG Q ++KKEYFI
Sbjct: 384 LCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 274 bits (701), Expect = 1e-73
Identities = 154/387 (39%), Positives = 230/387 (59%), Gaps = 11/387 (2%)
Query: 53 VWSSPDMLASQDSQP-WTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRA 111
++S+ ++ + D Q +T D TV+ G + CQV +DS +Q NP +QT+YF + R
Sbjct: 32 LFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRP 91
Query: 112 LRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG 171
L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + + +TVL P+ +I
Sbjct: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
Query: 172 YKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQ 231
K + E + +NC + SKPA + W KG+ EL G+ + ++E + +TV+S + +
Sbjct: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEWSD--MYTVTSQLMLK 208
Query: 232 VTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP---HPREGQKLLLHC 288
V +EDDG ++C V H ++ G + T + +EV Y P I+ P REG L L C
Sbjct: 209 VHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
Query: 289 EGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYT 347
E G P P W + + +P + L LNK+D+GTY C A++ +G + Y
Sbjct: 268 EAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
Query: 348 LNVNDPSPVPSSS--STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSD 405
L V D S + HA+IGG+VA +VF +L +LI LG Y RHKGTY THEAKG+D
Sbjct: 328 LYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGAD 387
Query: 406 DAPDADTAIINAEGGQSGGDDKKEYFI 432
DA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 388 DAADADTAIINAEGGQNNSEEKKEYFI 414
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 271 bits (692), Expect = 1e-72
Identities = 157/415 (37%), Positives = 236/415 (56%), Gaps = 39/415 (9%)
Query: 53 VWSSPDMLASQDSQP-WTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRA 111
++S+ ++ + D Q +T D TV+ G + CQV +DS +Q NP +QT+YF + R
Sbjct: 32 LFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRP 91
Query: 112 LRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG 171
L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + + +TVL P+ +I
Sbjct: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
Query: 172 YKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQ 231
K + E + +NC + SKPA + W KG+ EL G+ + ++E + +TV+S + +
Sbjct: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEWSD--MYTVTSQLMLK 208
Query: 232 VTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP---HPREGQKLLLHC 288
V +EDDG ++C V H ++ G + T + +EV Y P I+ P REG L L C
Sbjct: 209 VHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
Query: 289 EGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYT 347
E G P P W + + +P + L LNK+D+GTY C A++ +G + Y
Sbjct: 268 EAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
Query: 348 LNVNDPS---PVPSSSSTY---------------------------HAIIGGIVAFIVFL 377
L V DP P P++++T HA+IGG+VA +VF
Sbjct: 328 LYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAVDHAVIGGVVAVVVFA 387
Query: 378 LLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 432
+L +LI LG Y RHKGTY THEAKG+DDA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 388 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 442
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 227 bits (579), Expect = 1e-59
Identities = 136/375 (36%), Positives = 207/375 (55%), Gaps = 12/375 (3%)
Query: 61 ASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLV 120
A Q+ Q T + TV GG + C++ ++ S + NPA+QTL+F RAL+D R QL
Sbjct: 23 AGQEVQ--TENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNGTRALKDERFQLE 80
Query: 121 TSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD 180
+P + I +S+ L DEG Y C ++T + +TVL P+ P++ + ++ E
Sbjct: 81 EFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPVVEVREQAV-EGG 139
Query: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
L+C S+PAA L W + +EL G + NGK ++V+S+V F+V R+DDG
Sbjct: 140 EVELSCLVPRSRPAATLRWYRDRKELKGVSS---SQENGKVWSVASTVRFRVDRKDDGGI 196
Query: 241 IVCSVNHESL-KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQY 299
I+C +++L G + T ++V Y+PTA I REG L+L C GNP P Q
Sbjct: 197 IICEAQNQALPSGHSKQTQYVLDVQYSPTARIHASQAVVREGDTLVLTCAVTGNPRPNQI 256
Query: 300 LWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP-SPVP 357
W + S+P L P L +D+GTY C A++ G +A Y L V DP + V
Sbjct: 257 RWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVE 316
Query: 358 SSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINA 417
+ +S +AI+GGI+A +VFL++ +L+ + +R KG+YLTHEA G D+ +A A +N
Sbjct: 317 AQTSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLN- 375
Query: 418 EGGQSGGDDKKEYFI 432
G G K+E+FI
Sbjct: 376 --GSDGHKRKEEFFI 388
>gi|51593098 class-I MHC-restricted T cell associated molecule [Homo
sapiens]
Length = 393
Score = 95.1 bits (235), Expect = 1e-19
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 7/201 (3%)
Query: 69 TSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELS 128
T TV G T+ LKC ++SSLQW P+ T++ E AL++++ QL+ + ++LS
Sbjct: 23 TETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLS 82
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE---KDTATLN 185
I++ NV L DEG Y C ++ V T + V VL P KPI+ S +R+ ++ L
Sbjct: 83 ITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEA--SVIRKQNGEEHVVLM 140
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSV 245
C + SKP ++TW G+ T + + +GK +S++ ++ +++ C +
Sbjct: 141 CSTMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKN--STVDCII 198
Query: 246 NHESLKGADRSTSQRIEVLYT 266
H L+G R E L T
Sbjct: 199 RHRGLQGRKLVAPFRFEDLVT 219
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 94.4 bits (233), Expect = 2e-19
Identities = 75/258 (29%), Positives = 120/258 (46%), Gaps = 10/258 (3%)
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185
S+ + + + DEG YTC T P + ++S+ L + KP T K L +
Sbjct: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244
C S+G +P A++TW +L G P Q T TV+S + + DG ++ C
Sbjct: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303
V HES + T + V Y P I + GQ + L C+ R NP P Y W
Sbjct: 223 VEHESFEKPQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
Query: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSST 362
G +PP + Q + L+ ++K + T C T+ +G+ +A T+ V + P S +
Sbjct: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGIS 341
Query: 363 YHAIIGGIVAFIVFLLLI 380
+AII ++ +VFL+L+
Sbjct: 342 RNAIIFLVLGILVFLILL 359
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 94.4 bits (233), Expect = 2e-19
Identities = 75/258 (29%), Positives = 120/258 (46%), Gaps = 10/258 (3%)
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185
S+ + + + DEG YTC T P + ++S+ L + KP T K L +
Sbjct: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244
C S+G +P A++TW +L G P Q T TV+S + + DG ++ C
Sbjct: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303
V HES + T + V Y P I + GQ + L C+ R NP P Y W
Sbjct: 223 VEHESFEKPQLLTVN-LTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
Query: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSST 362
G +PP + Q + L+ ++K + T C T+ +G+ +A T+ V + P S +
Sbjct: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGIS 341
Query: 363 YHAIIGGIVAFIVFLLLI 380
+AII ++ +VFL+L+
Sbjct: 342 RNAIIFLVLGILVFLILL 359
>gi|239787787 kin of IRRE like 3 isoform 2 [Homo sapiens]
Length = 600
Score = 93.6 bits (231), Expect = 3e-19
Identities = 65/240 (27%), Positives = 106/240 (44%), Gaps = 8/240 (3%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST--PHELS 128
D+ VV+G V L C + ++ D + W + L G R L LV E
Sbjct: 56 DQVVVSGQPVTLLCAIPEY-DGFVLW---IKDGLALGVGRDLSSYPQYLVVGNHLSGEHH 111
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 187
+ I L D+ Y C +R+ + +TVL P P+I G SLR D L C
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCH 171
Query: 188 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNH 247
+ +KPAA + W + + ++G +GK ++ S++ ++G SIVC +
Sbjct: 172 ADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATN 231
Query: 248 ESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 307
+++ G + TS I++ + P + +P E + HC + NP QY W K G +
Sbjct: 232 KAIPGG-KETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQI 290
Score = 30.0 bits (66), Expect = 4.3
Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 23/186 (12%)
Query: 218 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 277
+G + ++T + R++D VC + +R + + P + H
Sbjct: 373 SGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVN---GPPIISSTQTQH 429
Query: 278 PREGQKLLLHCEGRGNPVPQQYLWEKEGSV----------PPLKMTQE---SALIFPFLN 324
G+K + C R P P + W + +V T+E S L +
Sbjct: 430 ALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
Query: 325 KSDSGT-YGCTATSNMGSYKAYYTL-----NVNDPSPVPSSSSTYHAIIG-GIVAFIVFL 377
++D T Y CTA ++ GS L + + + + S IIG + A + FL
Sbjct: 490 RADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFL 549
Query: 378 LLIMLI 383
+L+ I
Sbjct: 550 VLMATI 555
>gi|26006461 kin of IRRE like 3 isoform 1 [Homo sapiens]
Length = 778
Score = 93.6 bits (231), Expect = 3e-19
Identities = 65/240 (27%), Positives = 106/240 (44%), Gaps = 8/240 (3%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTST--PHELS 128
D+ VV+G V L C + ++ D + W + L G R L LV E
Sbjct: 56 DQVVVSGQPVTLLCAIPEY-DGFVLW---IKDGLALGVGRDLSSYPQYLVVGNHLSGEHH 111
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 187
+ I L D+ Y C +R+ + +TVL P P+I G SLR D L C
Sbjct: 112 LKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCH 171
Query: 188 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNH 247
+ +KPAA + W + + ++G +GK ++ S++ ++G SIVC +
Sbjct: 172 ADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATN 231
Query: 248 ESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV 307
+++ G + TS I++ + P + +P E + HC + NP QY W K G +
Sbjct: 232 KAIPGG-KETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQI 290
Score = 30.0 bits (66), Expect = 4.3
Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 23/186 (12%)
Query: 218 NGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPH 277
+G + ++T + R++D VC + +R + + P + H
Sbjct: 373 SGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVN---GPPIISSTQTQH 429
Query: 278 PREGQKLLLHCEGRGNPVPQQYLWEKEGSV----------PPLKMTQE---SALIFPFLN 324
G+K + C R P P + W + +V T+E S L +
Sbjct: 430 ALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIV 489
Query: 325 KSDSGT-YGCTATSNMGSYKAYYTL-----NVNDPSPVPSSSSTYHAIIG-GIVAFIVFL 377
++D T Y CTA ++ GS L + + + + S IIG + A + FL
Sbjct: 490 RADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFL 549
Query: 378 LLIMLI 383
+L+ I
Sbjct: 550 VLMATI 555
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 84.7 bits (208), Expect = 1e-16
Identities = 71/243 (29%), Positives = 109/243 (44%), Gaps = 11/243 (4%)
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185
S+ + + + DEG YTC T P + ++S+ L + KP T K L +
Sbjct: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244
C S+G +P A++TW +L G P Q T TV+S + + DG ++ C
Sbjct: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303
V HES + T + V Y P I + GQ + L C+ R NP P Y W
Sbjct: 223 VEHESFEKPQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
Query: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSST 362
G +PP + Q + L+ ++K + T C T+ +G+ +A T+ V + P S T
Sbjct: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKE-GPPSEHSGT 340
Query: 363 YHA 365
HA
Sbjct: 341 EHA 343
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 84.0 bits (206), Expect = 2e-16
Identities = 63/239 (26%), Positives = 112/239 (46%), Gaps = 8/239 (3%)
Query: 70 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRD-NRIQLVTSTPH-EL 127
+D+TVVAG VL C + ++ +QW+ L G + L+ R ++V S +
Sbjct: 28 ADQTVVAGQRAVLPCVLLNYS-GIVQWTKDG---LALGMGQGLKAWPRYRVVGSADAGQY 83
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTA-TLNC 186
++ I++ L+D+ Y C +R+ ++ +TVL P+ I G L + T L C
Sbjct: 84 NLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTC 143
Query: 187 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
++ +KPAA + W + + G + +GK T S + T D G C
Sbjct: 144 RAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSM 203
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG 305
+E++ + TS ++V + PT + +P +EG++++ C+ NP Y W K G
Sbjct: 204 NEAIPSG-KETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGG 261
Score = 54.3 bits (129), Expect = 2e-07
Identities = 66/307 (21%), Positives = 124/307 (40%), Gaps = 30/307 (9%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWS-NPAQQTLYF--GEKRALRDNRIQLVTSTPHEL 127
++T + GG V+L H + ++ PA ++F G ++ +L+ E
Sbjct: 121 EDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRET 180
Query: 128 SIS--ISNVALADEGE-YTCSIFTMPVRTAKSLVTVLGIPQKPIITGY--KSSLREKDTA 182
++S + N D G +TC + + K L + P +T +++E +
Sbjct: 181 TVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERV 240
Query: 183 TLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIV 242
CQ++ + W KG + ED + + + +F +
Sbjct: 241 VFTCQATANPEILGYRWAKGGFLI--------EDAHESRYETNVDYSFFTE------PVS 286
Query: 243 CSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWE 302
C V++ K + S + V + P ++ P P G + L C GNP P W
Sbjct: 287 CEVHN---KVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNP-PLTLTWT 342
Query: 303 KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTA-TSNMGSYKAYYTLNVNDPSPVPSSSS 361
K+ S + ++ + L+ + ++D+GTY C A +G + L VN P P+ SS +
Sbjct: 343 KKDS--NMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGP-PIISSEA 399
Query: 362 TYHAIIG 368
+A+ G
Sbjct: 400 VQYAVRG 406
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 82.8 bits (203), Expect = 6e-16
Identities = 67/254 (26%), Positives = 113/254 (44%), Gaps = 9/254 (3%)
Query: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 183
+ ++++ + + DEG YTC T P + + + T L + KP K + + T
Sbjct: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
Query: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243
C S +P AR++W + + T++ G T TV+S T + DG ++ C
Sbjct: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
Query: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 302
V HES + + V Y P I + G+ L C+ R NP P Y W
Sbjct: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
Query: 303 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361
G+ P + Q S L+ ++ + T+ CT T+ +G +A + V + +P + +
Sbjct: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPNTAGAG 356
Query: 362 TYHAIIGGIVAFIV 375
IIGGI+A I+
Sbjct: 357 ATGGIIGGIIAAII 370
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 82.0 bits (201), Expect = 9e-16
Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 22/283 (7%)
Query: 116 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 173
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
Query: 174 SSLREKD-----TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 226
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
Query: 227 SVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLL 285
+RE S+ C VN+ + + T + V Y P I D + +
Sbjct: 210 RYRLVPSREAHQQSLACIVNYHMDRFKESLT---LNVQYEPEVTIEGFDGNWYLQRMDVK 266
Query: 286 LHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYK 343
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 267 LTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTRS 326
Query: 344 AYYTLNVND-PSPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFL 385
+N+ + P P S + G + F++ + ++ + FL
Sbjct: 327 GQVEVNITEKPRPQRGLGSAARLLAGTVAVFLILVAVLTVFFL 369
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/281 (26%), Positives = 113/281 (40%), Gaps = 30/281 (10%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TV G L C + +H + + W N + LY G R D R++L+ +TP E SI I+
Sbjct: 43 TVCEGDNATLSCFIDEHV-TRVAWLNRSN-ILYAGNDRWTSDPRVRLLINTPEEFSILIT 100
Query: 133 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 192
V L DEG YTCS T + ++ +P + + ++ E L C + G +
Sbjct: 101 EVGLGDEGLYTCSFQTRHQPYTTQVYLIVHVPARIVNISSPVTVNEGGNVNLLCLAVG-R 159
Query: 193 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 252
P +TWR+ E G+ +S Q + V H +
Sbjct: 160 PEPTVTWRQLRDGFTSE---------GEILEISDIQRGQAGEYE-------CVTHNGVNS 203
Query: 253 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE------GS 306
A S + V Y PT + G+ LL CE P P + W K+ G+
Sbjct: 204 APDSRRVLVTVNYPPT-ITDVTSARTALGRAALLRCEAMAVP-PADFQWYKDDRLLSSGT 261
Query: 307 VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKA 344
LK+ E S L+F ++ G Y C A + +G+ A
Sbjct: 262 AEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSA 302
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 80.9 bits (198), Expect = 2e-15
Identities = 67/239 (28%), Positives = 107/239 (44%), Gaps = 10/239 (4%)
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG--YKSSLREKDTATLN 185
S+ + + + DEG YTC T P + ++S+ L + KP T K L +
Sbjct: 107 SLRMFGLRVEDEGNYTCLFVTFP-QGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMAR 165
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN-GKTFTVSSSVTFQVTREDDGASIVCS 244
C S+G +P A++TW +L G P Q T TV+S + + DG ++ C
Sbjct: 166 CVSTGGRPPAQITWHS---DLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCK 222
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWEK 303
V HES + T + V Y P I + GQ + L C+ R NP P Y W
Sbjct: 223 VEHESFEKPQLLT-VNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWST 281
Query: 304 E-GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361
G +PP + Q + L+ ++K + T C T+ +G+ +A T+ V +S++
Sbjct: 282 TMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKGTEHASASAN 340
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 80.1 bits (196), Expect = 4e-15
Identities = 76/288 (26%), Positives = 125/288 (43%), Gaps = 20/288 (6%)
Query: 124 PHELSISISNVALADEGEYTCSIFTMPVRT--AKSLVTVLGIPQKPIITGYKSSLREKDT 181
P + S+ + N ADEGEY C + T P + A+ + VL P + G + T
Sbjct: 107 PLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLT 166
Query: 182 ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASI 241
+C + GS PA +TW D E+ G T + + ++ V+S +R +G +
Sbjct: 167 LAASCTAEGS-PAPSVTW---DTEVKGT-TSSRSFKHSRSAAVTSEFHLVPSRSMNGQPL 221
Query: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHP-----REGQKLLLHCEGRGNPVP 296
C V+H L D+ + + V + A +R REG +L C G P P
Sbjct: 222 TCVVSHPGLL-QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGA--MLKCLSEGQP-P 277
Query: 297 QQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP-- 353
Y W + +G +P L FP L SG Y C ++ S + T++V DP
Sbjct: 278 PSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQE 337
Query: 354 -SPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHE 400
S + ++ G++A ++F LL++++ L R K +T +
Sbjct: 338 DSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 80.1 bits (196), Expect = 4e-15
Identities = 77/297 (25%), Positives = 129/297 (43%), Gaps = 21/297 (7%)
Query: 73 TVVAGGTVVLKCQVKDHED-SSLQWSN---PAQQTL------YFGEKRALRDNRIQLVTS 122
T V G V LKC ++ +E + + W + QT+ Y + R+
Sbjct: 67 TAVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNY 126
Query: 123 TPHELSISISNVALADEGEYTCSIFTMPVRTAKS--LVTVLGIPQKPIITGYKSSL-REK 179
+ ++ +I++ N+ +D G+Y C T P+ A+S VTVL P +I G S +
Sbjct: 127 SLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGN 186
Query: 180 DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA 239
+T C ++ KP A + W E+ T PN +T T+ S TR G
Sbjct: 187 ETVAAICIAATGKPVAHIDWEGDLGEMESTTTSF---PN-ETATIISQYKLFPTRFARGR 242
Query: 240 SIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQK-LLLHCEGRGNPVPQQ 298
I C V H +L+ D S +++ Y P + + G+K + L C NP P +
Sbjct: 243 RITCVVKHPALE-KDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFK 301
Query: 299 YLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
+W + +G P + ++ L F L + SG Y C T+++G + ++DP
Sbjct: 302 SVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDP 358
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 79.7 bits (195), Expect = 5e-15
Identities = 88/306 (28%), Positives = 133/306 (43%), Gaps = 33/306 (10%)
Query: 116 RIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYK 173
R++ + + + +I +S + L DEG Y C T P +S + L + KP I G +
Sbjct: 96 RVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGNRESQLN-LTVMAKPTNWIEGTQ 154
Query: 174 SSLREK-----DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE--DPNGKTFTVSS 226
+ LR K C S+ KP + ++W + L GE QE +PNG T TV S
Sbjct: 155 AVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLKGE-AEYQEIRNPNG-TVTVIS 209
Query: 227 SVTFQVTREDDGASIVCSVNHESLKGADR-STSQRIEVLYTPTAMIRP-DPPHPREGQKL 284
+RE S+ C VN+ DR S + V Y P I D + +
Sbjct: 210 RYRLVPSREAHQQSLACIVNYH----MDRFKESLTLNVQYEPEVTIEGFDGNWYLQRMDV 265
Query: 285 LLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPF-LNKSDSGTYGCTATSNMGSY 342
L C+ NP +Y W GS+P Q L F +N S +GTY C AT+ +G+
Sbjct: 266 KLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPINYSLAGTYICEATNPIGTR 325
Query: 343 KAYYTLNVND----PSPVP---SSSSTYHAIIGGIVAFIVFLLLI---MLIFLGHYLIRH 392
+N+ + PSP + AIIGG+ I+ +L++ +++ L
Sbjct: 326 SGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGSILLVLIVVGGIVVALRRRRHTF 385
Query: 393 KGTYLT 398
KG Y T
Sbjct: 386 KGDYST 391
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 78.2 bits (191), Expect = 1e-14
Identities = 75/326 (23%), Positives = 128/326 (39%), Gaps = 37/326 (11%)
Query: 67 PWTSDETVVA--GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTP 124
PW + + ++ G T VL+C ++D W N + G+K ++ D R+ + T
Sbjct: 41 PWAAVDNMMVRKGDTAVLRCYLEDGASKGA-WLNRSSIIFAGGDKWSV-DPRVSISTLNK 98
Query: 125 HELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL 184
+ S+ I NV + D+G YTCS+ T + + +P K ++ E TL
Sbjct: 99 RDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTL 158
Query: 185 NCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCS 244
C ++G KP ++WR P+ K F + D CS
Sbjct: 159 TCLATG-KPEPSISWR-------------HISPSAKPFENGQYLDIYGITRDQAGEYECS 204
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAM-IRPDPPHPREGQKLLLHCEGRGNPVP------- 296
++ R ++ V + PT I+ P G+ L+ CEG G P P
Sbjct: 205 AENDVSFPDVRKV--KVVVNFAPTIQEIKSGTVTP--GRSGLIRCEGAGVPPPAFEWYKG 260
Query: 297 QQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 356
++ L+ + + + S L + + G Y C A + +G+ A LN
Sbjct: 261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN------- 313
Query: 357 PSSSSTYHAIIGGIVAFIVFLLLIML 382
P S++ Y V F + L++ L
Sbjct: 314 PPSTAQYGITGSADVLFSCWYLVLTL 339
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 76.6 bits (187), Expect = 4e-14
Identities = 68/270 (25%), Positives = 116/270 (42%), Gaps = 9/270 (3%)
Query: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPI--ITGYKSSLREKDTAT 183
+ ++++ + + DEG YTC T P + + + T L + KP K + + T
Sbjct: 122 DATLALHGLTVEDEGNYTCEFATFPKGSVRGM-TWLRVIAKPKNQAEAQKVTFSQDPTTV 180
Query: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243
C S +P AR++W + + T++ G T TV+S T + DG ++ C
Sbjct: 181 ALCISKEGRPPARISWLSS-LDWEAKETQVSGTLAG-TVTVTSRFTLVPSGRADGVTVTC 238
Query: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQ-KLLLHCEGRGNPVPQQYLWE 302
V HES + + V Y P I + G+ L C+ R NP P Y W
Sbjct: 239 KVEHESFE-EPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWS 297
Query: 303 -KEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361
G+ P + Q S L+ ++ + T+ CT T+ +G +A + V + +P S
Sbjct: 298 TTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRE-TPRASPRD 356
Query: 362 TYHAIIGGIVAFIVFLLLIMLIFLGHYLIR 391
+ G + ++ LLL+ L L+R
Sbjct: 357 VGPLVWGAVGGTLLVLLLLAGGSLAFILLR 386
>gi|68163411 activated leukocyte cell adhesion molecule [Homo
sapiens]
Length = 583
Score = 75.5 bits (184), Expect = 9e-14
Identities = 57/220 (25%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Query: 128 SISISNVALADEGEYTCSIFTMP-VRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL-N 185
++SISN ++DE + C + T V A ++V V P KP I L + L +
Sbjct: 97 TLSISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLETEQLKKLGD 156
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRI------QEDPNGKTFTVSSSVTFQVTREDDGA 239
C S S P +TW + + LH + + DP + +T++S++ ++ T+ D
Sbjct: 157 CISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQLYTMTSTLEYKTTKADIQM 216
Query: 240 SIVCSVNHESLKGADRSTS-QRIEVLYTPTAMIR----PDPPHPREGQKLLLHCEGRGNP 294
CSV + G S Q + +Y PT + P +EG + L C G GNP
Sbjct: 217 PFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQVTIQVLPPKNAIKEGDNITLKCLGNGNP 276
Query: 295 VPQQYLWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGCT 334
P+++L+ G P + + + ++ +G Y C+
Sbjct: 277 PPEEFLFYLPGQ--PEGIRSSNTYTLTDVRRNATGDYKCS 314
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 74.3 bits (181), Expect = 2e-13
Identities = 70/238 (29%), Positives = 102/238 (42%), Gaps = 23/238 (9%)
Query: 131 ISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQKPIITGYKSS-LREKDTATLNC 186
I N+ + + G YTC RT + +TV P KP IT S+ + ++D L C
Sbjct: 286 IPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTC 345
Query: 187 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
+ W +Q L P R+Q + +T T+ S VTR D G C +
Sbjct: 346 EPEIQN--TTYLWWVNNQSLPVSP-RLQLSNDNRTLTLLS-----VTRNDVG-PYECGIQ 396
Query: 247 HESLKGADRSTSQRIEVLYTP-TAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG 305
++ D S + VLY P I P + R G L L C NP P QY W +G
Sbjct: 397 NK--LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNP-PAQYSWLIDG 453
Query: 306 SVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYK--AYYTLNVNDPSPVPSSSS 361
++ + TQE L + + +SG Y C A ++ + T+ V+ P PS SS
Sbjct: 454 NIQ--QHTQE--LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISS 507
Score = 73.9 bits (180), Expect = 3e-13
Identities = 76/256 (29%), Positives = 107/256 (41%), Gaps = 25/256 (9%)
Query: 125 HELSISISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQKPIITGYKSS-LREKD 180
H + ISN+ + G YTC RT +TV KP I+ S + +KD
Sbjct: 458 HTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKD 517
Query: 181 TATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGAS 240
C+ L W G Q L P R+Q +T T+ F VTR +D +
Sbjct: 518 AVAFTCEPEAQN-TTYLWWVNG-QSLPVSP-RLQLSNGNRTLTL-----FNVTR-NDARA 568
Query: 241 IVCSVNHESLKGADRSTSQRIEVLYTP-TAMIRPDPPHPREGQKLLLHCEGRGNPVPQQY 299
VC + + A+RS ++VLY P T +I P G L L C NP P QY
Sbjct: 569 YVCGIQNSV--SANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSP-QY 625
Query: 300 LWEKEGSVPPLKMTQESALIFPFLNKSDSGTYGC----TATSNMGSYKAYYTLNVNDPSP 355
W G P + TQ L + +++GTY C AT S T++ + SP
Sbjct: 626 SWRINGI--PQQHTQ--VLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
Query: 356 VPSSSSTYHAIIGGIV 371
S+ +T +IG +V
Sbjct: 682 GLSAGATVGIMIGVLV 697
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 73.2 bits (178), Expect = 4e-13
Identities = 74/294 (25%), Positives = 124/294 (42%), Gaps = 26/294 (8%)
Query: 62 SQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVT 121
S D T + TV G T +L+C V+D ++S + W N + ++ G + D R++L
Sbjct: 31 SVDFNRGTDNITVRQGDTAILRCVVED-KNSKVAWLNRSG-IIFAGHDKWSLDPRVELEK 88
Query: 122 STPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDT 181
E S+ I V + DEG YTCS+ T + ++ +P K ++ E
Sbjct: 89 RHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSN 148
Query: 182 ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASI 241
TL C ++G +P +TWR H PT + + + + +TRE G
Sbjct: 149 VTLVCMANG-RPEPVITWR------HLTPTGREFEGEEEYLEI-----LGITREQSG-KY 195
Query: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLW 301
C +E + AD ++ V Y PT + G++ L CE P P + W
Sbjct: 196 ECKAANE-VSSAD-VKQVKVTVNYPPT-ITESKSNEATTGRQASLKCEASAVPAP-DFEW 251
Query: 302 EKE------GSVPPLKMTQ-ESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL 348
++ + +K T+ +S+L + + G Y C A + +G A L
Sbjct: 252 YRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVL 305
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 72.8 bits (177), Expect = 6e-13
Identities = 84/338 (24%), Positives = 138/338 (40%), Gaps = 31/338 (9%)
Query: 44 PLDEAISSTVWSSPDMLASQ--DSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQ 101
PL A SS ++ + S D +P + D V+AG + +C V + + WS +
Sbjct: 6252 PLGTASSSARLTAREPKKSPFFDIKPVSID--VIAGESADFECHVTGAQPMRITWSKDNK 6309
Query: 102 QTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVL 161
E R + I V +TPH + I V D G+YTC + S +
Sbjct: 6310 ------EIRPGGNYTITCVGNTPH---LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSV 6360
Query: 162 GIPQKPIITGYKSSL-REKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGK 220
P K + S + ++ ++ L C+ SGS P +++W + D ELH E + N
Sbjct: 6361 KEPPKFVKKLEASKVAKQGESIQLECKISGS-PEIKVSWFRNDSELH-ESWKY----NMS 6414
Query: 221 TFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPRE 280
+ +T +D +C ++ D S S + V P +P P +
Sbjct: 6415 FINSVALLTINEASAEDSGDYICEAHNGV---GDASCSTALTVKAPPVFTQKPSPVGALK 6471
Query: 281 GQKLLLHCEGRGNPVPQQYLWEKE----GSVPPLKMTQ---ESALIFPFLNKSDSGTYGC 333
G ++L CE G P P + +W K+ + K+T +++L L SD G Y C
Sbjct: 6472 GSDVILQCEISGTP-PFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHC 6530
Query: 334 TATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIV 371
AT+ +GS ++ +P S +IG V
Sbjct: 6531 KATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAV 6568
Score = 59.3 bits (142), Expect = 7e-09
Identities = 77/339 (22%), Positives = 132/339 (38%), Gaps = 39/339 (11%)
Query: 44 PLDEAISST--VWSSPDMLASQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQ 101
PL A SS + S ++ D +P + D + GT KC V + W+
Sbjct: 7193 PLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGT--FKCHVTGTAPIKITWAK--- 7247
Query: 102 QTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVL 161
+ R +R +T + ++++ V D G+YTC + + S L
Sbjct: 7248 ------DNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTC--YASNIAGKDSCSAQL 7299
Query: 162 GIPQKP-IITGYKSS--LREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPN 218
G+ + P I + S +++ + C+ GS P ++ W K + T IQE
Sbjct: 7300 GVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGS-PEIKVLWYKDE-------TEIQESSK 7351
Query: 219 GKTFTVSSSVTFQVTR--EDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP 276
+ V S ++ +D C H + A STS ++V P +P P
Sbjct: 7352 FRMSFVDSVAVLEMHNLSVEDSGDYTCEA-HNAAGSASSSTS--LKVKEPPIFRKKPHPI 7408
Query: 277 HPREGQKLLLHCEGRGNPVPQQYLWEKEG----SVPPLKMTQESALIFPFL---NKSDSG 329
+G + L CE +G P P W K+ S K+ E+ L + + +D G
Sbjct: 7409 ETLKGADVHLECELQGTP-PFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIG 7467
Query: 330 TYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIG 368
Y C AT+++GS ++ + P S ++G
Sbjct: 7468 EYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVG 7506
Score = 56.6 bits (135), Expect = 4e-08
Identities = 62/275 (22%), Positives = 108/275 (39%), Gaps = 32/275 (11%)
Query: 99 PAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLV 158
P + +++ +KR LR ++ + S SI I NV +D GEY C + + V
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCK--AQNEVGSDTCV 5601
Query: 159 TVLGIPQKPIITGYKSSLR--EKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 216
+ + + P +SL + A L G++P + W K +E+ I+E
Sbjct: 5602 CTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIF-VQWLKEKEEV------IRES 5654
Query: 217 PNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPD 274
N + V + T Q + + + +C + ++ G R + VL + +
Sbjct: 5655 ENIRITFVENVATLQFAKAEPANAGKYICQIKND---GGMRENMATLMVLEPAVIVEKAG 5711
Query: 275 PPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLNK--------- 325
P G+ L C+ G P W K+G + +T F F NK
Sbjct: 5712 PMTVTVGETCTLECKVAGTP-ELSVEWYKDGKL----LTSSQKHKFSFYNKISSLRILSV 5766
Query: 326 --SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 358
D+GTY +N+G ++V+D + PS
Sbjct: 5767 ERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPS 5801
Score = 55.8 bits (133), Expect = 7e-08
Identities = 67/299 (22%), Positives = 117/299 (39%), Gaps = 50/299 (16%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 136
G +V L+CQV + ++ W Y G+ + LR T + ++ + V +
Sbjct: 6093 GDSVSLQCQVAGTPEITVSW--------YKGDTK-LRPTPEYRTYFTNNVATLVFNKVNI 6143
Query: 137 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTA-----TLNCQSSGS 191
D GEYTC + TA S TV I ++ + + L++ + TL C+ +GS
Sbjct: 6144 NDSGEYTCKAENS-IGTASSK-TVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS 6201
Query: 192 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHES 249
P +R G +++D N +T V + T ++ + D CS ++
Sbjct: 6202 APIQVCWYRDG--------VLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPL 6253
Query: 250 LKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE----- 304
+ + E +P I+P G+ C G P + W K+
Sbjct: 6254 GTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQ-PMRITWSKDNKEIR 6312
Query: 305 ----------GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
G+ P L++ + + K DSG Y C AT+++G L+V +P
Sbjct: 6313 PGGNYTITCVGNTPHLRILK--------VGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 6363
Score = 52.4 bits (124), Expect = 8e-07
Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 34/292 (11%)
Query: 74 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 133
V G C+++ + QW ++ +Y +K ++R S+ + S+ I
Sbjct: 3467 VALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR--------SSKYISSLEILR 3517
Query: 134 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE--KDTATLNCQSSGS 191
+ D GEYTC + + + P SL A C +G+
Sbjct: 3518 TQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGT 3577
Query: 192 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLK 251
P W+K L P D K S++T Q D C +++
Sbjct: 3578 -PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQ-----DRGVYSCKASNKF-- 3629
Query: 252 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHC---EGRGNPVPQQYLWEKEGS-V 307
GAD ++ I ++ P + +P +K+ L C E R V W K+G +
Sbjct: 3630 GADICQAELI-IIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVT----WSKDGQKL 3684
Query: 308 PPLK------MTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
PP K + + L P DSGTY CTA++ GS T+ V +P
Sbjct: 3685 PPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP 3736
Score = 51.6 bits (122), Expect = 1e-06
Identities = 75/322 (23%), Positives = 130/322 (40%), Gaps = 39/322 (12%)
Query: 65 SQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTP 124
++P + D V+ G V LK S+ Q S P + G K + +T
Sbjct: 4210 TKPGSKD--VLPGSAVCLK--------STFQGSTPLTIRWFKGNKELVSGGSCY-ITKEA 4258
Query: 125 HELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTAT- 183
E S+ + V +D G YTC + + S + P + S L +K AT
Sbjct: 4259 LESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQ 4318
Query: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRE--DDGASI 241
L C+ +G+ P ++TW D+E I+E + V S+ ++T +D
Sbjct: 4319 LACKVTGTPPI-KITWFANDRE-------IKESSKHRMSFVESTAVLRLTDVGIEDSGEY 4370
Query: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLW 301
+C +E+ G+D +S I V +P P + ++L E G P P + W
Sbjct: 4371 MCEAQNEA--GSDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTP-PFEITW 4426
Query: 302 EKEGSVPPLKMTQE----------SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVN 351
K+ ++ L+ ++ S I F+ +D+G Y C T+ +GS + +
Sbjct: 4427 FKDNTI--LRSGRKYKTFIQDHLVSLQILKFV-AADAGEYQCRVTNEVGSSICSARVTLR 4483
Query: 352 DPSPVPSSSSTYHAIIGGIVAF 373
+P + ++ GG AF
Sbjct: 4484 EPPSFIKKIESTSSLRGGTAAF 4505
Score = 51.6 bits (122), Expect = 1e-06
Identities = 63/311 (20%), Positives = 119/311 (38%), Gaps = 40/311 (12%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 136
G V+L+C++ P + ++ +++ +R+++ +TS + S+ I N+
Sbjct: 6472 GSDVILQCEIS---------GTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEA 6522
Query: 137 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR 196
+D GEY C S P + + +S D L G +P +
Sbjct: 6523 SDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPIS- 6581
Query: 197 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQV--TREDDGASIVCSVNHESLKGAD 254
+ W K E+ I+E N + + + T Q+ + +C + +++
Sbjct: 6582 VVWLKDRGEV------IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDA---GM 6632
Query: 255 RSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQ 314
R S + VL + +P+P G L C G P W K+G +++
Sbjct: 6633 RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTP-ELSAKWFKDGR----ELSA 6687
Query: 315 ESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS---SS 360
+S F+NK SD G Y +++G +++V+D PS
Sbjct: 6688 DSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKL 6747
Query: 361 STYHAIIGGIV 371
+AI+G V
Sbjct: 6748 KDVNAILGASV 6758
Score = 50.4 bits (119), Expect = 3e-06
Identities = 69/308 (22%), Positives = 117/308 (37%), Gaps = 49/308 (15%)
Query: 70 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSI 129
SD +V G +++L+ S+ W F + + N + +T +
Sbjct: 5993 SDHSVEPGKSIILESTYTGTLPISVTWKKDG-----FNITTSEKCN----IVTTEKTCIL 6043
Query: 130 SISNVALADEGEYTCSIFTMPVR-TAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 187
I N D G+Y+C I R +LV+ L P +T + D+ +L CQ
Sbjct: 6044 EILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPY--FVTELEPLEAAVGDSVSLQCQ 6101
Query: 188 SSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVT--FQVTREDDGASIVCSV 245
+G+ P ++W KGD T+++ P +T+ ++ T F +D C
Sbjct: 6102 VAGT-PEITVSWYKGD-------TKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA 6153
Query: 246 NHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 304
+ S+ A T RI+ P + R G + L C G+ P Q W ++
Sbjct: 6154 EN-SIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS-APIQVCWYRD 6211
Query: 305 G---------------SVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLN 349
G +V LK+ Q S SG Y C+A++ +G+ + L
Sbjct: 6212 GVLLRDDENLQTSFVDNVATLKILQTDL--------SHSGQYSCSASNPLGTASSSARLT 6263
Query: 350 VNDPSPVP 357
+P P
Sbjct: 6264 AREPKKSP 6271
Score = 50.4 bits (119), Expect = 3e-06
Identities = 74/316 (23%), Positives = 120/316 (37%), Gaps = 32/316 (10%)
Query: 70 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEK-RALRDNRIQLVTSTPHELS 128
SD + V G V L+ ++ E S+ W F +K +R++ ++ + + +
Sbjct: 7499 SDISTVVGKEVQLQTTIEGAEPISVVW---------FKDKGEIVRESDNIWISYSENIAT 7549
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK--DTATLNC 186
+ S V A+ G+YTC I + L + + I S++ DT TL C
Sbjct: 7550 LQFSRVEPANAGKYTCQIKNDA--GMQECFATLSVLEPATIVEKPESIKVTTGDTCTLEC 7607
Query: 187 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
+G+ P W K +EL + N VS V D G V S
Sbjct: 7608 TVAGT-PELSTKWFKDGKELTSDNKYKISFFN----KVSGLKIINVAPSDSG---VYSFE 7659
Query: 247 HESLKGADRSTS--QRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 304
++ G D T+ Q + P+ + + G +++ C+ G+P P W E
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSP-PISVSWFHE 7718
Query: 305 GSVPPLKMTQES-------ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVP 357
G+ ++ AL L +SDSG Y C AT+ GS + L V +P
Sbjct: 7719 GNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFV 7778
Query: 358 SSSSTYHAIIGGIVAF 373
+ G V F
Sbjct: 7779 QKPDPMDVLTGTNVTF 7794
Score = 49.7 bits (117), Expect = 5e-06
Identities = 68/299 (22%), Positives = 122/299 (40%), Gaps = 34/299 (11%)
Query: 74 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 133
V G + L+CQ+ + + W Y G+ + LR + + ++ +
Sbjct: 7972 VSVGDSASLQCQLAGTPEIGVSW--------YKGDTK-LRPTTTYKMHFRNNVATLVFNQ 8022
Query: 134 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLRE-KDTATL----NCQS 188
V + D GEY C + S T L + ++ + + LR+ ++T L +C
Sbjct: 8023 VDINDSGEYICKAENSVGEVSAS--TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAI 8080
Query: 189 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 248
SGS+P + ++W K G+P +++ PN +T + ++ T + + D + S
Sbjct: 8081 SGSEPIS-VSWYKD-----GKP--LKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTAT 8132
Query: 249 SLKGADRSTSQRI--EVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE-- 304
+ G+ S+++ I E P IR P G+ C G P + W K+
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQ-PIKVSWAKDSR 8191
Query: 305 ----GSVPPLKMTQESA-LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 358
G + + SA L ++K DSG Y C A + +G LN+ + PS
Sbjct: 8192 EIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPS 8250
Score = 48.1 bits (113), Expect = 2e-05
Identities = 64/292 (21%), Positives = 110/292 (37%), Gaps = 30/292 (10%)
Query: 74 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 133
++ G + L C++K +P Q +F + L ++ + E + I++
Sbjct: 3749 MLPGESARLHCKLK---------GSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITD 3799
Query: 134 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKP 193
V + D G Y+C + S V+ P I T + + A L C+ SG+ P
Sbjct: 3800 VKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP 3859
Query: 194 AARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQV--TREDDGASIVCSVNHESLK 251
++W K + +I+ + F+ S V ++ D C V +E K
Sbjct: 3860 -FEISWFK-------DKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 3911
Query: 252 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK-------E 304
+T E PT + + D GQ + L RG+ P W K +
Sbjct: 3912 CGCMATHLLKE---PPTFVKKVDDLIALGGQTVTLQAAVRGSE-PISVTWMKGQEVIRED 3967
Query: 305 GSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 356
G + + LI P + S G Y C A + GS + L V +P+ +
Sbjct: 3968 GKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKI 4019
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/252 (22%), Positives = 108/252 (42%), Gaps = 26/252 (10%)
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKP-IITGYKSS--LREKDTATLN 185
+++ +V + G+YTC + T V + S T+L + + P + ++S ++ D++ L
Sbjct: 5387 LNLYSVDASKTGQYTCHV-TNDVGS-DSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLE 5444
Query: 186 CQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTR--EDDGASIVC 243
C+ +GS P R+ W + + EL D TF + S Q+ +D +C
Sbjct: 5445 CKIAGS-PEIRVVWFRNEHELPAS------DKYRMTF-IDSVAVIQMNNLSTEDSGDFIC 5496
Query: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK 303
+ + S S ++ V P P + ++ L CE G P P + +W K
Sbjct: 5497 EAQNPA---GSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTP-PFEVVWYK 5552
Query: 304 EG----SVPPLKMTQES---ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 356
+ S K+ ++ ++ ++ SD G Y C A + +GS T+ + +P
Sbjct: 5553 DKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRF 5612
Query: 357 PSSSSTYHAIIG 368
S ++ + G
Sbjct: 5613 VSKLNSLTVVAG 5624
Score = 46.2 bits (108), Expect = 6e-05
Identities = 61/287 (21%), Positives = 112/287 (39%), Gaps = 31/287 (10%)
Query: 85 QVKDHEDSSLQWS---NPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGE 141
QV + ++L+++ P + ++ + R L ++ ++ + + + L D G+
Sbjct: 4027 QVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQ 4086
Query: 142 YTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKD-----TATLNCQSSGSKPAAR 196
YT I + S T + + I + LR D T L+C+ +GS P R
Sbjct: 4087 YTFEISNEV--GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPM-R 4143
Query: 197 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKGAD 254
++W K +E I + V + + ++ R D D + C +
Sbjct: 4144 VSWFKDGKE-------IAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSV---GS 4193
Query: 255 RSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE-------GSV 307
+ +S + V P+ + +P G + L +G+ P W K GS
Sbjct: 4194 KDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGS-TPLTIRWFKGNKELVSGGSC 4252
Query: 308 PPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPS 354
K ES+L + SDSGTY C ++ G + L V +P+
Sbjct: 4253 YITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 4299
Score = 45.8 bits (107), Expect = 7e-05
Identities = 57/232 (24%), Positives = 94/232 (40%), Gaps = 20/232 (8%)
Query: 120 VTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREK 179
+T+T + I + + D G+Y C I + + S ++ P + +
Sbjct: 7916 ITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVG 7975
Query: 180 DTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA 239
D+A+L CQ +G+ P ++W KGD +L T N V++ V QV D G
Sbjct: 7976 DSASLQCQLAGT-PEIGVSWYKGDTKLRPTTTYKMHFRN----NVATLVFNQVDINDSGE 8030
Query: 240 SIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQ 298
I + N S+ ST ++ P + R G ++ C G+ P
Sbjct: 8031 YICKAEN--SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSE-PIS 8087
Query: 299 YLWEKEGSVPPLK---------MTQESALIFPFLNKSDSGTYGCTATSNMGS 341
W K+G PLK + + L ++S +G Y CTAT+ +GS
Sbjct: 8088 VSWYKDGK--PLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 8137
Score = 45.1 bits (105), Expect = 1e-04
Identities = 65/290 (22%), Positives = 119/290 (41%), Gaps = 34/290 (11%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELS-ISISNVA 135
G V +C++ E + W + + L+D+ L TS H ++ + I
Sbjct: 7130 GFPVAFECRINGSEPLQVSW---------YKDGVLLKDDA-NLQTSFVHNVATLQILQTD 7179
Query: 136 LADEGEYTCSIFTMPVRTAKSLVTVL----GIPQKPIITGYKSSLREKDTATLNCQSSGS 191
+ G+Y CS + P+ TA S ++ +P + L ++ T C +G+
Sbjct: 7180 QSHIGQYNCSA-SNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGT 7238
Query: 192 KPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLK 251
P ++TW K ++E I+ N K V ++ T V + G + + ++
Sbjct: 7239 API-KITWAKDNRE-------IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIA 7290
Query: 252 GADRSTSQRIEVLYTPTAMIRPDPPH-PREGQKLLLHCEGRGNPVPQQYLWEK------E 304
G D S S ++ V P + + +P ++ + C+ G+P + LW K E
Sbjct: 7291 GKD-SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSP-EIKVLWYKDETEIQE 7348
Query: 305 GSVPPLKMTQESALI-FPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
S + A++ L+ DSG Y C A + GS + +L V +P
Sbjct: 7349 SSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP 7398
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/297 (21%), Positives = 112/297 (37%), Gaps = 41/297 (13%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 136
G V L+C+++ + W + +KR LR + + S SI I NV
Sbjct: 7413 GADVHLECELQGTPPFHVSW---------YKDKRELRSGKKYKIMSENFLTSIHILNVDA 7463
Query: 137 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSS--GSKPA 194
AD GEY C T V + + V + + P S + + Q++ G++P
Sbjct: 7464 ADIGEYQCKA-TNDV-GSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPI 7521
Query: 195 ARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRED--DGASIVCSVNHESLKG 252
+ + W K E+ ++E N + T Q +R + + C + +++
Sbjct: 7522 S-VVWFKDKGEI------VRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDA--- 7571
Query: 253 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKM 312
+ + VL T + +P+ G L C G P W K+G ++
Sbjct: 7572 GMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTP-ELSTKWFKDGK----EL 7626
Query: 313 TQESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 358
T ++ F NK SDSG Y + +G +L V+D + PS
Sbjct: 7627 TSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPS 7683
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 15/238 (6%)
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 188
+ + +V + GEYTC + + + + + P K + S+ + L
Sbjct: 7832 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTF 7891
Query: 189 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 248
+G+ P + +TW+K +G + N T S+ + + +D C + E
Sbjct: 7892 TGTPPIS-VTWKK-----NGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYI--E 7943
Query: 249 SLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVP 308
+ G D S S +I +L P + + +P G L C+ G P ++ + +
Sbjct: 7944 NASGKD-SCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLR 8002
Query: 309 PL---KM---TQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSS 360
P KM + L+F ++ +DSG Y C A +++G A L V + PS S
Sbjct: 8003 PTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8060
Score = 43.5 bits (101), Expect = 4e-04
Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 131 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSG 190
I+ L DE EY+C VRTA++ + + ++ + T +++ +T T+
Sbjct: 12432 INKCLLDDEAEYSCE-----VRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV 12486
Query: 191 SKPAARLTWRKGDQEL 206
SKP A + W KGD+E+
Sbjct: 12487 SKPGAEVIWYKGDEEI 12502
Score = 43.1 bits (100), Expect = 5e-04
Identities = 61/291 (20%), Positives = 104/291 (35%), Gaps = 35/291 (12%)
Query: 75 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGE-KRALRDNRIQLVTSTPHELSISISN 133
+ G + L+C V S+QW Q+ + K + DN L IS
Sbjct: 4687 IKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFL----------EISQ 4736
Query: 134 VALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKP 193
+ D G YTCS S + P + + L G+ P
Sbjct: 4737 LEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAP 4796
Query: 194 AARLTWRKGDQELHGEPTR-IQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 252
+ W K ++ELH R + +D S+S+ + D + +C ++++
Sbjct: 4797 MT-IKWFKDNKELHSGAARSVWKDDT------STSLELFAAKATDSGTYICQLSNDVGTA 4849
Query: 253 ADRSTSQRIEVLYTPTAMIRPDPPHP-REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLK 311
++T + V P + +P P R GQ C+ G P + W +G+ +
Sbjct: 4850 TSKAT---LFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTP-KIRVSWYLDGN--EIT 4903
Query: 312 MTQESALIF---------PFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
Q+ + F +SGTY C A ++ G+ L V +P
Sbjct: 4904 AIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEP 4954
Score = 42.7 bits (99), Expect = 6e-04
Identities = 65/317 (20%), Positives = 120/317 (37%), Gaps = 41/317 (12%)
Query: 75 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNV 134
V G + +C V + + W+ + R +R ++ + +++ V
Sbjct: 8165 VVGESADFECHVTGTQPIKVSWAK---------DSREIRSGGKYQISYLENSAHLTVLKV 8215
Query: 135 ALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTAT------LNCQS 188
D G+YTC + + S L I ++ I + L E T L +
Sbjct: 8216 DKGDSGQYTC--YAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRV 8273
Query: 189 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTRE--DDGASIVCSVN 246
+GS+P + W K + E IQ N + ++++ QV + +D C V+
Sbjct: 8274 AGSQPIT-VAWYKNNIE-------IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVS 8325
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 306
+++ S+ E P P EG+ + L C +G+ P + W K G
Sbjct: 8326 NDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE-PIRIQWLKAGR 8384
Query: 307 VPPLKMTQESALIFPF---------LNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVP 357
+K + + F + K+DSG Y C A++ GS + + D V
Sbjct: 8385 --EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAV- 8441
Query: 358 SSSSTYHAIIGGIVAFI 374
+ +T A + G + F+
Sbjct: 8442 -APATKKAAVDGRLFFV 8457
Score = 42.0 bits (97), Expect = 0.001
Identities = 68/306 (22%), Positives = 115/306 (37%), Gaps = 54/306 (17%)
Query: 75 VAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNV 134
V G ++ ++C+V S QW ++ + R + R +S+ ++N+
Sbjct: 5249 VLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHER---------SVSLEVNNL 5299
Query: 135 ALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPA 194
L D YTC + + A S + + P ++ + T G+ P
Sbjct: 5300 ELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGT-PP 5358
Query: 195 ARLTWRKGDQELHGEPTRIQEDPNGKT-----FTVSSSVTFQVTREDDGASIVCSVNHES 249
++ W K D EL P + G T ++V +S T Q T C V ++
Sbjct: 5359 FKIKWFKDDVELVSGP-KCFIGLEGSTSFLNLYSVDASKTGQYT---------CHVTND- 5407
Query: 250 LKGADRSTSQRIEVLYTPTAMIRPDPPH----------PREGQKLLLHCEGRGNPVPQQY 299
G+D T T ++ +PP + G L C+ G+P +
Sbjct: 5408 -VGSDSCT----------TMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVV 5456
Query: 300 LWEKEGSVP---PLKMT-QESALIFPFLNKS--DSGTYGCTATSNMGSYKAYYTLNVNDP 353
+ E +P +MT +S + N S DSG + C A + GS + V +P
Sbjct: 5457 WFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP 5516
Query: 354 SPVPSS 359
PV SS
Sbjct: 5517 -PVFSS 5521
Score = 42.0 bits (97), Expect = 0.001
Identities = 65/319 (20%), Positives = 117/319 (36%), Gaps = 30/319 (9%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TVVAG L+ ++ + +QW ++ + R++ +T + ++ +
Sbjct: 5620 TVVAGEPAELQASIEGAQPIFVQWLKEKEEVI--------RESENIRITFVENVATLQFA 5671
Query: 133 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 192
A+ G+Y C I ++ P + ++ +T TL C+ +G+
Sbjct: 5672 KAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGT- 5730
Query: 193 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKG 252
P + W K + L T Q+ +SS V R+D G + V + K
Sbjct: 5731 PELSVEWYKDGKLL----TSSQKHKFSFYNKISSLRILSVERQDAG-TYTFQVQNNVGKS 5785
Query: 253 ADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGN-PVPQQYLWEKEGSVPPLK 311
+ + + P+ R G +L C+ G+ P+ + EK V K
Sbjct: 5786 SCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAK 5845
Query: 312 MTQESA-----LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP----------SPV 356
+ L L+ SD G Y C A + GS + L V +P +
Sbjct: 5846 YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVL 5905
Query: 357 PSSSSTYHAIIGGIVAFIV 375
P + T+ ++I G F V
Sbjct: 5906 PGKNVTFTSVIRGTPPFKV 5924
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/298 (24%), Positives = 116/298 (38%), Gaps = 45/298 (15%)
Query: 74 VVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISN 133
V G L+ + ++ + +W Q+ L G K + VT T L I +
Sbjct: 4590 VTQGDPATLQVKFSGTKEITAKWFKDGQE-LTLGSKYKIS------VTDTVSILKII--S 4640
Query: 134 VALADEGEYTCSIFTMPVRTA-KSLVTVLGIPQKPIITGYKSSLREKDTAT-----LNCQ 187
D GEYT + R++ K+ + VL + P T L++ D+ L C
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFT---KKLKKMDSIKGSFIDLECI 4697
Query: 188 SSGSKPAARLTWRKGDQELHG-EPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
+GS P + + W K DQE+ E + N +S Q+ D G + CS
Sbjct: 4698 VAGSHPIS-IQWFKDDQEISASEKYKFSFHDNTAFLEIS-----QLEGTDSG-TYTCSAT 4750
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDP----PHPREGQKLLLHCEGRGNPVPQQYLWE 302
+ K S + V P + +P P+ R K L+ G P W
Sbjct: 4751 N---KAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALV-----GGTAPMTIKWF 4802
Query: 303 KE------GSVPPLKMTQESALIFPFLNKS-DSGTYGCTATSNMGSYKAYYTLNVNDP 353
K+ G+ + S + F K+ DSGTY C ++++G+ + TL V +P
Sbjct: 4803 KDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Score = 38.5 bits (88), Expect = 0.012
Identities = 43/236 (18%), Positives = 90/236 (38%), Gaps = 15/236 (6%)
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 188
+ + N+ ++ GEYTC + + + + + P + S+ + L
Sbjct: 5950 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTY 6009
Query: 189 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 248
+G+ P + +TW+K G E N T + + + + D C + +E
Sbjct: 6010 TGTLPIS-VTWKKD-----GFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENE 6063
Query: 249 SLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVP 308
+ + + +E Y T + +P G + L C+ G P ++ + +
Sbjct: 6064 AGRDVCGALVSTLEPPYFVTEL---EPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 6120
Query: 309 PLK------MTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPS 358
P + L+F +N +DSG Y C A +++G+ + + + PS
Sbjct: 6121 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPS 6176
Score = 38.5 bits (88), Expect = 0.012
Identities = 28/88 (31%), Positives = 37/88 (42%), Gaps = 11/88 (12%)
Query: 279 REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT---------QESALIFPFLNKSDSG 329
+ G + L RG P P+ W K+ L + S +SD G
Sbjct: 18214 KAGDTIRLEAGVRGKPFPE-VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272
Query: 330 TYGCTATSNMGSYKAYYTLNVND-PSPV 356
Y TAT+ GS+ AY T+NV D P PV
Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPV 18300
Score = 37.7 bits (86), Expect = 0.020
Identities = 57/291 (19%), Positives = 110/291 (37%), Gaps = 37/291 (12%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 136
GGT + +K ++ W + + R +N + S+ +S + +
Sbjct: 4500 GGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVA---------SLYLSGIEV 4550
Query: 137 ADEGEYTCSIFT-MPVRTAKSLVTVLGIPQKPIITGYKSSL--REKDTATLNCQSSGSKP 193
+G+Y C ++ +L L + + IT S+ + D ATL + SG+K
Sbjct: 4551 KHDGKYVCQAKNDAGIQRCSAL---LSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKE 4607
Query: 194 AARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGA 253
++ G + G +I T TVS ++D G V ++ + +
Sbjct: 4608 ITAKWFKDGQELTLGSKYKISV-----TDTVSILKIISTEKKDSG-EYTFEVQNDVGRSS 4661
Query: 254 DRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT 313
++ ++++ P+ + +G + L C G+ P W K+ +++
Sbjct: 4662 CKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSH-PISIQWFKDDQ----EIS 4716
Query: 314 QESALIFPF-----------LNKSDSGTYGCTATSNMGSYKAYYTLNVNDP 353
F F L +DSGTY C+AT+ G + L V +P
Sbjct: 4717 ASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP 4767
Score = 37.0 bits (84), Expect = 0.035
Identities = 65/303 (21%), Positives = 112/303 (36%), Gaps = 51/303 (16%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TV G L+C V + S +W F + R L + +T S+ I
Sbjct: 6655 TVTTGNPFALECVVTGTPELSAKW---------FKDGRELSADSKHHITFINKVASLKIP 6705
Query: 133 NVALADEGEYTCSIFTMPVRTAKSLVTV-LGIPQKPIITGYKSSLREKD-----TATLNC 186
++D+G Y+ F + KS TV + + + + + L++ + + L C
Sbjct: 6706 CAEMSDKGLYS---FEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLEC 6762
Query: 187 QSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
+ SGS P + ++ G++ + G + N T +S + D G + N
Sbjct: 6763 RVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSL-----LEPSDTGIYTCVAAN 6817
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK--- 303
+ G+D ++ + V P+ PD G L RG P P + W K
Sbjct: 6818 ---VAGSDECSAV-LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTP-PFKVKWFKGSR 6872
Query: 304 ------------EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVN 351
E V L++ + L +SG Y C T++ GS L V
Sbjct: 6873 ELVPGESCNISLEDFVTELELFEVQPL--------ESGDYSCLVTNDAGSASCTTHLFVK 6924
Query: 352 DPS 354
+P+
Sbjct: 6925 EPA 6927
Score = 36.2 bits (82), Expect = 0.059
Identities = 67/326 (20%), Positives = 125/326 (38%), Gaps = 38/326 (11%)
Query: 70 SDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSI 129
SD + + G V L+ V+ + S+ W + + R + RI + + ++
Sbjct: 6558 SDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVI-----RESENTRISFIDNIA---TL 6609
Query: 130 SISNVALADEGEYTCSIFT-MPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQS 188
+ + ++ G+Y C I +R +++TVL P + I ++ + L C
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-PARIIEKPEPMTVTTGNPFALECVV 6668
Query: 189 SGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHE 248
+G+ P W K +EL + + TF ++ + ++ + + S +
Sbjct: 6669 TGT-PELSAKWFKDGRELSAD------SKHHITF-INKVASLKIPCAEMSDKGLYSFEVK 6720
Query: 249 SLKGADRST-SQRIEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG- 305
+ G T S + P + IR + G ++L C G+ P W ++G
Sbjct: 6721 NSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS-APISVGWFQDGN 6779
Query: 306 ---SVPPLKMTQES---ALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP------ 353
S P + + L L SD+G Y C A + GS + L V +P
Sbjct: 6780 EIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT 6839
Query: 354 ----SPVPSSSSTYHAIIGGIVAFIV 375
+P S T+ ++I G F V
Sbjct: 6840 PDSVEVLPGMSLTFTSVIRGTPPFKV 6865
Score = 36.2 bits (82), Expect = 0.059
Identities = 55/219 (25%), Positives = 89/219 (40%), Gaps = 40/219 (18%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHEL-SI 129
D T+ G T + CQ +S P ++ +F R L+ + T H++ +
Sbjct: 8753 DVTLKEGQTCTMTCQ----------FSVPNVKSEWFRNGRILKPQG-RHKTEVEHKVHKL 8801
Query: 130 SISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSS---LREKDTATLNC 186
+I++V D+G+YTC + L I +PI + + E +AT C
Sbjct: 8802 TIADVRAEDQGQYTCKYEDLETSAE------LRIEAEPIQFTKRIQNIVVSEHQSATFEC 8855
Query: 187 QSSGSKPAARLTWRKGDQEL-HGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSV 245
+ S A +TW KG EL + + D T+ + VT +D+G V +
Sbjct: 8856 EVSFDD--AIVTWYKGPTELTESQKYNFRNDGRCHYMTIHN-----VTPDDEGVYSV--I 8906
Query: 246 NHESLKGADRSTSQRIEVLYTPTAMIR-----PDPPHPR 279
+G RST++ LY T I+ PD P R
Sbjct: 8907 ARLEPRGEARSTAE----LYLTTKEIKLELKPPDIPDSR 8941
Score = 35.8 bits (81), Expect = 0.078
Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 254 DRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT 313
++ST+++I+ + +P EG+ C+ G PVP W ++G V
Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVP-TVTWLRKGQVLSTSAR 32606
Query: 314 QE-------SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNV 350
+ S + SD G Y ++ G +A +TL +
Sbjct: 32607 HQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 16/128 (12%)
Query: 249 SLKGADRSTSQRIEV--LYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 306
++K DR T+ +++ + T ++R G + L +G P P +W K S
Sbjct: 28345 TIKAVDRLTAPELDIDANFKQTHVVRA-------GASIRLFIAYQGRPTPTA-VWSKPDS 28396
Query: 307 VPPLKMTQESALIFPFL-----NKSDSGTYGCTATSNMGSYKAYYTLNVNDPSPVPSSSS 361
L+ + F L N++D+G Y T +N GS +T+ V D +P P
Sbjct: 28397 NLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLD-TPGPPGPI 28455
Query: 362 TYHAIIGG 369
T+ + G
Sbjct: 28456 TFKDVTRG 28463
Score = 34.3 bits (77), Expect = 0.23
Identities = 34/141 (24%), Positives = 56/141 (39%), Gaps = 25/141 (17%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSIS 130
D+TV G T VL+C+V E++ ++W + L + + D R++ +
Sbjct: 12293 DQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR---------KLV 12342
Query: 131 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSL-----REKDTATLN 185
I + D YTC AK T + P + L REK+ A
Sbjct: 12343 IHDCTPEDIKTYTCD--------AKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFE 12394
Query: 186 CQSSGSKPAARLTWRKGDQEL 206
C+ S+ A++ W K E+
Sbjct: 12395 CEL--SRENAKVKWFKDGAEI 12413
Score = 33.9 bits (76), Expect = 0.29
Identities = 53/229 (23%), Positives = 89/229 (38%), Gaps = 30/229 (13%)
Query: 152 RTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPT 211
RTA TV I GY++S+ ATL + S + A ++T + T
Sbjct: 810 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSET 869
Query: 212 RIQEDPN--------GKTFTVSSSVTFQVTREDDGASI----VCSVNHESLKGADRSTSQ 259
R++ +P T S +V +E G SI V E L G + ++
Sbjct: 870 RVRAEPTPLPQFPFADTPDTYKSEAGVEVKKE-VGVSITGTTVREERFEVLHGREAKVTE 928
Query: 260 R------IEVLYTPTAMIRP-DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEG----SVP 308
+E+ TP ++ EG+ + L C G P P W +E S
Sbjct: 929 TARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSP-TVTWYREDYQIESSI 987
Query: 309 PLKMTQESALIFPFLNKS---DSGTYGCTATSNMG--SYKAYYTLNVND 352
++T +S + + ++ DSG + C+A + G S Y + V++
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 33.9 bits (76), Expect = 0.29
Identities = 52/270 (19%), Positives = 106/270 (39%), Gaps = 27/270 (10%)
Query: 99 PAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLV 158
P + +F R ++++ ++ + +++V + D GEY C S +
Sbjct: 4327 PPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI 4386
Query: 159 TVLGIPQKPIITG-YK--SSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQE 215
+ + + P T +K L+E D L + +G+ P +TW K + T ++
Sbjct: 4387 VI--VKESPYFTKEFKPIEVLKEYDVMLL-AEVAGTPPF-EITWFKDN-------TILRS 4435
Query: 216 DPNGKTFTVSSSVTFQVTR--EDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRP 273
KTF V+ Q+ + D C V +E S R+ + P+ + +
Sbjct: 4436 GRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEV---GSSICSARVTLREPPSFIKKI 4492
Query: 274 DPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFLNKSD-- 327
+ G +G+ +P W K+ ++MT E+ + +L+ +
Sbjct: 4493 ESTSSLRGGTAAFQATLKGS-LPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVK 4551
Query: 328 -SGTYGCTATSNMGSYKAYYTLNVNDPSPV 356
G Y C A ++ G + L+V +P+ +
Sbjct: 4552 HDGKYVCQAKNDAGIQRCSALLSVKEPATI 4581
Score = 33.5 bits (75), Expect = 0.38
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 22/152 (14%)
Query: 230 FQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLY------TPTAMIRP---DPPHPRE 280
F VT +G + ++ GA + S+ E + PT ++ P D +
Sbjct: 20333 FTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKA 20392
Query: 281 GQKLLLHCEG-RGNPVPQQYLWEKEGS-VPPLKMTQ------ESALIFPFLNKSDSGTYG 332
G ++L+ G P+P+ W K G + P +TQ S L + + D+G Y
Sbjct: 20393 GDTIVLNAISILGKPLPKSS-WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 20451
Query: 333 CTATSNMGSYKAYYTLNVND----PSPVPSSS 360
TAT+ G+ + + V D P PV S+
Sbjct: 20452 ITATNPFGTKVEHVKVTVLDVPGPPGPVEISN 20483
Score = 33.5 bits (75), Expect = 0.38
Identities = 56/253 (22%), Positives = 91/253 (35%), Gaps = 62/253 (24%)
Query: 148 TMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR-LTWRKGDQEL 206
T P T K V L + P IT + + K+ A L C S A+ +TW K ++L
Sbjct: 32701 TKPTPTEK--VQHLPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKL 32758
Query: 207 HGEPTRIQEDPNGK-TFTVSSSVTFQVT----REDDGASIVCSVN--------------- 246
NG F S+ T+++ E D VC ++
Sbjct: 32759 K---------ENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQ 32809
Query: 247 -----HESL-KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLH------------- 287
HE + K ++ S + T T P P P + +++
Sbjct: 32810 AFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVA 32869
Query: 288 ---CEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFLNK---SDSGTYGCTATS 337
+ G P P +W K+G K++++ F ++K SDSG Y CT +
Sbjct: 32870 KFAVKATGEPRPTA-IWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKN 32928
Query: 338 NMGSYKAYYTLNV 350
+ GS + L +
Sbjct: 32929 SAGSVSSSCKLTI 32941
Score = 33.1 bits (74), Expect = 0.50
Identities = 33/114 (28%), Positives = 45/114 (39%), Gaps = 13/114 (11%)
Query: 73 TVVAGGTVVLKC-QVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISI 131
T+ AG T+VL + WS + +R + I +TSTP ++I
Sbjct: 20389 TIKAGDTIVLNAISILGKPLPKSSWSKAGKD---------IRPSDITQITSTPTSSMLTI 20439
Query: 132 SNVALADEGEYTCSIFTMPVRTAKS--LVTVLGIPQKPIITGYKSSLREKDTAT 183
D GEYT + T P T VTVL +P P + EK T T
Sbjct: 20440 KYATRKDAGEYTITA-TNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLT 20492
Score = 32.7 bits (73), Expect = 0.66
Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 25/145 (17%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TV G V L C V+ E +QW R ++ + + + +
Sbjct: 8356 TVSEGEYVQLSCHVQGSEPIRIQWLKAG---------REIKPSDRCSFSFASGTAVLELR 8406
Query: 133 NVALADEGEYTCSIFTMP-VRTAKSLVTVLGIP------QKPIITG------YKSSLR-- 177
+VA AD G+Y C + T KS VT+ P +K + G S+R
Sbjct: 8407 DVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVV 8466
Query: 178 EKDTATLNCQSSGSKPAARLTWRKG 202
EK TAT + G P + W KG
Sbjct: 8467 EKTTATFIAKVGGD-PIPNVKWTKG 8490
Score = 32.7 bits (73), Expect = 0.66
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query: 279 REGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQESALIFPFL---NKSDSGTY 331
+ G + L G P+P W+K+G++ +KM + L L N+ DSG Y
Sbjct: 19308 KAGTNVCLDATVFGKPMPT-VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 332 GCTATSNMGSYKAYYTLNVNDPSPVPSS 359
TA ++ GS A L V D P+S
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPAS 19394
Score = 31.6 bits (70), Expect = 1.5
Identities = 34/142 (23%), Positives = 57/142 (40%), Gaps = 25/142 (17%)
Query: 175 SLREKDTATLNCQSSGSKPAARLTWRKGDQELH-GEPTRIQEDPNGKTFTVSSSVTFQVT 233
+++ DT LN S KP + +W K +++ + T+I P T+ T
Sbjct: 20389 TIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIK-----YAT 20443
Query: 234 REDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPRE-----GQKLLL-- 286
R+D G + + N K + ++V T + P PP P E +K L
Sbjct: 20444 RKDAGEYTITATNPFGTK------VEHVKV----TVLDVPGPPGPVEISNVSAEKATLTW 20493
Query: 287 --HCEGRGNPVPQQYLWEKEGS 306
E G+P+ L ++E S
Sbjct: 20494 TPPLEDGGSPIKSYILEKRETS 20515
Score = 31.6 bits (70), Expect = 1.5
Identities = 43/184 (23%), Positives = 66/184 (35%), Gaps = 17/184 (9%)
Query: 175 SLREKDTATLNCQSSGSKPAARLTWRKGDQEL-HGEPTRIQEDPNGKTFTVSSSVTFQVT 233
S+ E L +G A + W EL + E R + +T T+ Q +
Sbjct: 33049 SINEGQRLVLKANIAG---ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIK-----QAS 33100
Query: 234 REDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGN 293
D+G S E + + E+ P + +P + EGQ +L CE G
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 33160
Query: 294 PVPQQYLWEK-------EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYY 346
P P + W K +V + +L + SDSG Y A + G A
Sbjct: 33161 PSP-EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATA 33219
Query: 347 TLNV 350
+L V
Sbjct: 33220 SLMV 33223
Score = 31.6 bits (70), Expect = 1.5
Identities = 61/311 (19%), Positives = 110/311 (35%), Gaps = 53/311 (17%)
Query: 65 SQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTP 124
SQP + + G V+ C++ ++W F + + ++ +
Sbjct: 33138 SQP--RSQNINEGQNVLFTCEISGEPSPEIEW---------FKNNLPISISSNVSISRSR 33186
Query: 125 HELSISISNVALADEGEY-------------TCSIFTMPVRTAKSLVTVLGIPQKPIITG 171
+ S+ I N +++D G+Y T S+ +P+ S VL + G
Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246
Query: 172 YKSSLREKDTAT---LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSV 228
SS + +A+ + S S A+ +T K + +QE +F SS
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQE-----SFVEMSSS 33301
Query: 229 TFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHC 288
+F + + S + LK R +IE L P EG+ L + C
Sbjct: 33302 SFMGI---SNMTQLESSTSKMLKAGIRGIPPKIEAL--------PSDISIDEGKVLTVAC 33350
Query: 289 EGRGNPVPQQYLW---------EKEGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNM 339
G P P + W +++G + LI + K D G Y + +
Sbjct: 33351 AFTGEPTP-EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEF 33409
Query: 340 GSYKAYYTLNV 350
GS A +++
Sbjct: 33410 GSDSATVNIHI 33420
Score = 31.2 bits (69), Expect = 1.9
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQ-LVTSTPHELSI 129
D V+ G VL+C+V + +S++W Y +++ D+R+Q +V T L I
Sbjct: 2453 DVNVIEGTKAVLECKVSVPDVTSVKW--------YLNDEQIKPDDRVQAIVKGTKQRLVI 2504
Query: 130 SISNVALADEGEY 142
+ ++ +DEG Y
Sbjct: 2505 NRTHA--SDEGPY 2515
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/329 (21%), Positives = 121/329 (36%), Gaps = 58/329 (17%)
Query: 55 SSPDMLA-SQDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALR 113
S+P++ A ++DS T V GGT + ++ + ++W+ ++TL LR
Sbjct: 24906 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTL-----TDLR 24960
Query: 114 DNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYK 173
L +E ++ N A E S+F R +L G P P +T
Sbjct: 24961 LRVTGLTEGHSYEFRVAAENAAGVGEPSEP-SVF---YRACDALYPP-GPPSNPKVT--- 25012
Query: 174 SSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSV----- 228
DT+ + + SKP G + G ++E + T +
Sbjct: 25013 ------DTSRSSVSLAWSKPIY-----DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGK 25061
Query: 229 TFQVTREDDGASI---VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHP------- 278
F VT+ + +C++N E + + + + A R +PP
Sbjct: 25062 QFTVTKLKENTEYNFRICAINSEGV-------GEPATLPGSVVAQERIEPPEIELDADLR 25114
Query: 279 -----REGQKLLLHCEGRGNPVPQQYLWEKEGSV----PPLKMTQE-SALIFPFLNKSDS 328
R L L +G P P+ WEK + +++T + L+ + + DS
Sbjct: 25115 KVVVLRASATLRLFVTIKGRPEPE-VKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS 25173
Query: 329 GTYGCTATSNMGSYKAYYTLNVNDPSPVP 357
G Y T +N GS A+ + V D P
Sbjct: 25174 GRYNLTLENNSGSKTAFVNVRVLDSPSAP 25202
Score = 30.8 bits (68), Expect = 2.5
Identities = 54/296 (18%), Positives = 106/296 (35%), Gaps = 44/296 (14%)
Query: 77 GGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVAL 136
G + +CQ+ + W L E A++ + I + + IS +
Sbjct: 4876 GQSTTFECQITGTPKIRVSWY------LDGNEITAIQKHGISFIDGLA---TFQISGARV 4926
Query: 137 ADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAAR 196
+ G Y C + S+ + P I + + L C+ +G+ P
Sbjct: 4927 ENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPF-E 4985
Query: 197 LTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVT---FQVTRED--DGASIVCSVNHESLK 251
+TW K ++E+ + K +T++ V+ +T+ D D C V++E
Sbjct: 4986 VTWLKNNREIR----------SSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNE--- 5032
Query: 252 GADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLK 311
G S S R+ + P+ + + + G+P P W K+ +
Sbjct: 5033 GGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSP-PISITWLKDDQI---- 5087
Query: 312 MTQESALIFPFLNK-----------SDSGTYGCTATSNMGSYKAYYTLNVNDPSPV 356
+ ++ + F++ SG Y C A + G + Y L V +P+ +
Sbjct: 5088 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI 5143
Score = 30.4 bits (67), Expect = 3.3
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 281 GQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMT-----QESALIFPFLNKSDSGTYGCTA 335
G+ L + G PVP + ++EG + ++ +S LI + D G Y TA
Sbjct: 15119 GKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITA 15178
Query: 336 TSNMGSYKAYYTLNVND-PSPV 356
T++ GS A + V D P PV
Sbjct: 15179 TNSCGSKFAAARVEVFDVPGPV 15200
Score = 30.4 bits (67), Expect = 3.3
Identities = 84/375 (22%), Positives = 136/375 (36%), Gaps = 73/375 (19%)
Query: 32 WQEQDLELGTLAPLDEAISSTVWSSPDMLASQDSQPWTSDETVVAGGTVVLKCQVKD--- 88
W + D +L T A +D S T + + + + + + V++ ++ L +V D
Sbjct: 26220 WSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG 26279
Query: 89 -----------HEDSSLQWSNP-----AQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
E + L W P A Y EKR VT+ + LS ++
Sbjct: 26280 PPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVT 26339
Query: 133 NVA--------LADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATL 184
N+ ++ E E+ I P T + + I +KP S EK T
Sbjct: 26340 NLQEGAIYYFRVSGENEFGVGI---PAETKEGVK----ITEKP-------SPPEKLGVT- 26384
Query: 185 NCQSSGSKPAARLTWRK-----GDQELHGEPTRIQE-DPNGKTFTVSSSVTFQVTREDDG 238
S SK + LTW K G + +H +++ N V+ S V+ +
Sbjct: 26385 ----SISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLREN 26440
Query: 239 ASIVCSVNHESLKGADRSTSQRIEVLYT-----PTAMIRPDPPHP---REGQKLLLHCEG 290
+ V E+ G + VL P ++ P H R G L +
Sbjct: 26441 SEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPI 26500
Query: 291 RGNPVPQQYLWEKEGSVPPLKMTQESALIFPFLN---------KSDSGTYGCTATSNMGS 341
G P+P+ L ++G PLK T N +D+G Y TA ++ G+
Sbjct: 26501 SGKPLPKVTL-SRDGV--PLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGT 26557
Query: 342 YKAYYTLNVND-PSP 355
KA+ + V D P P
Sbjct: 26558 TKAFINIVVLDRPGP 26572
Score = 30.0 bits (66), Expect = 4.3
Identities = 58/240 (24%), Positives = 90/240 (37%), Gaps = 37/240 (15%)
Query: 128 SISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQ 187
S++I NV D +YT + TA V I + I K + EK A C+
Sbjct: 3024 SLNIRNVHFGDAADYTF-VAGKATSTATLYVEARHIEFRKHIKDIK--VLEKKRAMFECE 3080
Query: 188 SSGSKPAARLTWRKGDQELH-GEPTRIQEDPNGKTFTVSSSVTFQVTREDDGA--SIVCS 244
S +P + W K DQEL + +IQ++ + S TR D ++V
Sbjct: 3081 VS--EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPS------TRMSDAGKYTVVAG 3132
Query: 245 VNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKE 304
N + K RI + +I E Q+ ++ E + V W K+
Sbjct: 3133 GNVSTAKLFVEGRDVRIRSIKKEVQVI--------EKQRAVVEFEVNEDDVDAH--WYKD 3182
Query: 305 GSVPPLKMTQESALIFP------FLN---KSDSGTYGCTATSNMGSYKAYYTLNVNDPSP 355
G ++ + + F++ +SD+G Y A N S TL VN P P
Sbjct: 3183 GIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS----VTLYVNAPEP 3238
Score = 29.6 bits (65), Expect = 5.6
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 71 DETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSIS 130
D+T V + LKC+V +D ++W ++ + K +++ + ++ + +
Sbjct: 11671 DKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVP-SPKYSIKADGLRRI--------LK 11719
Query: 131 ISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSG 190
I L D+GEY C T + ++ L +KP+ Y + +TA +
Sbjct: 11720 IKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL---YGVEVFVGETAHFEIEL-- 11774
Query: 191 SKPAARLTWRKGDQELHGEP 210
S+P W+ Q L P
Sbjct: 11775 SEPDVHGQWKLKGQPLTASP 11794
Score = 29.3 bits (64), Expect = 7.3
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 15/99 (15%)
Query: 271 IRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGSV-----PPLKMTQESA-------- 317
+R D + G+ + + + G P+P+ W K +V L++T+E
Sbjct: 15403 VRGDTIKVKAGEPVHIPADVTGLPMPK-IEWSKNETVIEKPTDALQITKEEVSRSEAKTE 15461
Query: 318 LIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVND-PSP 355
L P + D GTY TA++ +GS + V D PSP
Sbjct: 15462 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSP 15500
Score = 29.3 bits (64), Expect = 7.3
Identities = 15/44 (34%), Positives = 22/44 (50%)
Query: 307 VPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNV 350
V L + L+ P +SD+G Y TA +N+G+ LNV
Sbjct: 16170 VNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 28.9 bits (63), Expect = 9.5
Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 12/104 (11%)
Query: 279 REGQKLLLHCEGRGNPVPQQYLWEKEGSVPPLKMTQ----ESALIFPFLN-----KSDSG 329
+ G + + G P P W+K + LK TQ E+ LN +SDSG
Sbjct: 21078 KAGDNIKVEIPVLGRPKPT-VTWKKGDQI--LKQTQRVNFETTATSTILNINECVRSDSG 21134
Query: 330 TYGCTATSNMGSYKAYYTLNVNDPSPVPSSSSTYHAIIGGIVAF 373
Y TA + +G T+ V+D P+ + + V F
Sbjct: 21135 PYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 21178
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 72.4 bits (176), Expect = 7e-13
Identities = 74/286 (25%), Positives = 128/286 (44%), Gaps = 30/286 (10%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TV G + L+C + D + + W N + LY G + D R+ ++ +TP + SI I
Sbjct: 39 TVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 96
Query: 133 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 192
NV + DEG YTCS+ T + ++ +P + + ++ E + TL C + G +
Sbjct: 97 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG-R 155
Query: 193 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVT--REDDGASIVCSVNHESL 250
P +TWR ++E G+ F VS +++ + D CS ++
Sbjct: 156 PEPTVTWRH---------LSVKE---GQGF-VSEDEYLEISDIKRDQSGEYECSALNDVA 202
Query: 251 KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS---- 306
R +I V Y P + + GQK +L CE P+ + + W KE +
Sbjct: 203 APDVRKV--KITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAE-FQWFKEETRLAT 258
Query: 307 -VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL 348
+ +++ + S L F +++ D G Y C AT+ +G+ A TL
Sbjct: 259 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 304
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 72.4 bits (176), Expect = 7e-13
Identities = 74/286 (25%), Positives = 128/286 (44%), Gaps = 30/286 (10%)
Query: 73 TVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISIS 132
TV G + L+C + D + + W N + LY G + D R+ ++ +TP + SI I
Sbjct: 46 TVRQGESATLRCTIDDRV-TRVAWLNRST-ILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
Query: 133 NVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSK 192
NV + DEG YTCS+ T + ++ +P + + ++ E + TL C + G +
Sbjct: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG-R 162
Query: 193 PAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVT--REDDGASIVCSVNHESL 250
P +TWR ++E G+ F VS +++ + D CS ++
Sbjct: 163 PEPTVTWRH---------LSVKE---GQGF-VSEDEYLEISDIKRDQSGEYECSALNDVA 209
Query: 251 KGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS---- 306
R +I V Y P + + GQK +L CE P+ + + W KE +
Sbjct: 210 APDVRKV--KITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAE-FQWFKEETRLAT 265
Query: 307 -VPPLKMTQE---SALIFPFLNKSDSGTYGCTATSNMGSYKAYYTL 348
+ +++ + S L F +++ D G Y C AT+ +G+ A TL
Sbjct: 266 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
Length = 708
Score = 72.4 bits (176), Expect = 7e-13
Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 3/180 (1%)
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 187
+ I V L DE Y C +R+ + + VL P+ P + G S SL A L C+
Sbjct: 88 LHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCR 147
Query: 188 SSG-SKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
S G ++P L W + L G G +V S++T DDGA+ VC
Sbjct: 148 SRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRAR 207
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 306
++L R T+ + + Y P + P +EG+K++ C+ P Y W K GS
Sbjct: 208 SQALP-TGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVTGYRWAKGGS 266
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/249 (23%), Positives = 105/249 (42%), Gaps = 26/249 (10%)
Query: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS--SLREKDTAT 183
E +++++ + D + C + + T + L + P +T S +++E +
Sbjct: 186 ESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVI 245
Query: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243
CQ++ P W KG G P P + +S +T V+ C
Sbjct: 246 FLCQATAQPPVTGYRWAKG-----GSPVLGARGPRLEVVADASFLTEPVS---------C 291
Query: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK 303
V++ ++ A+RST+ ++VL+ P +P+P G+ C RGNP+P + W +
Sbjct: 292 EVSN-AVGSANRSTA--LDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLP-RVTWTR 347
Query: 304 EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYK---AYYTLNVNDPSPVPSSS 360
G L + L P + D+G Y C A + + + A L VN P PV ++
Sbjct: 348 RGGAQVL--GSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAP-PVVTAL 404
Query: 361 STYHAIIGG 369
+ A + G
Sbjct: 405 HSAPAFLRG 413
>gi|145275172 kin of IRRE-like 2 isoform b [Homo sapiens]
Length = 583
Score = 72.4 bits (176), Expect = 7e-13
Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 3/180 (1%)
Query: 129 ISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS-SLREKDTATLNCQ 187
+ I V L DE Y C +R+ + + VL P+ P + G S SL A L C+
Sbjct: 38 LHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCR 97
Query: 188 SSG-SKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVN 246
S G ++P L W + L G G +V S++T DDGA+ VC
Sbjct: 98 SRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRAR 157
Query: 247 HESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEKEGS 306
++L R T+ + + Y P + P +EG+K++ C+ P Y W K GS
Sbjct: 158 SQALP-TGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVTGYRWAKGGS 216
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/249 (23%), Positives = 105/249 (42%), Gaps = 26/249 (10%)
Query: 126 ELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITGYKS--SLREKDTAT 183
E +++++ + D + C + + T + L + P +T S +++E +
Sbjct: 136 ESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVI 195
Query: 184 LNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVC 243
CQ++ P W KG G P P + +S +T V+ C
Sbjct: 196 FLCQATAQPPVTGYRWAKG-----GSPVLGARGPRLEVVADASFLTEPVS---------C 241
Query: 244 SVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHPREGQKLLLHCEGRGNPVPQQYLWEK 303
V++ ++ A+RST+ ++VL+ P +P+P G+ C RGNP+P + W +
Sbjct: 242 EVSN-AVGSANRSTA--LDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLP-RVTWTR 297
Query: 304 EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYK---AYYTLNVNDPSPVPSSS 360
G L + L P + D+G Y C A + + + A L VN P PV ++
Sbjct: 298 RGGAQVL--GSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAP-PVVTAL 354
Query: 361 STYHAIIGG 369
+ A + G
Sbjct: 355 HSAPAFLRG 363
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,341,465
Number of Sequences: 37866
Number of extensions: 895597
Number of successful extensions: 4148
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 285
Number of HSP's that attempted gapping in prelim test: 2379
Number of HSP's gapped (non-prelim): 1416
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.