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Search of human proteins with 156564390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
(503 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 1016 0.0
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 981 0.0
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 695 0.0
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 695 0.0
gi|19923195 carcinoembryonic antigen-related cell adhesion molec... 197 2e-50
gi|68161541 carcinoembryonic antigen-related cell adhesion molec... 191 2e-48
gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 156 4e-38
gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 105 1e-22
gi|85861202 carcinoembryonic antigen-related cell adhesion molec... 103 3e-22
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi... 101 1e-21
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens] 100 3e-21
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [... 100 4e-21
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ... 100 4e-21
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [... 100 4e-21
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ... 97 3e-20
gi|21314600 carcinoembryonic antigen-related cell adhesion molec... 96 8e-20
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi... 96 8e-20
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 94 4e-19
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 93 6e-19
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi... 93 6e-19
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 91 2e-18
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ... 91 2e-18
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu... 86 1e-16
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi... 82 1e-15
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2... 82 1e-15
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2... 82 1e-15
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1... 82 1e-15
gi|148612793 carcinoembryonic antigen-related cell adhesion mole... 81 2e-15
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [... 80 6e-15
gi|52317156 carcinoembryonic antigen-related cell adhesion molec... 79 7e-15
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 1016 bits (2628), Expect = 0.0
Identities = 503/503 (100%), Positives = 503/503 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
Query: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN
Sbjct: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
Query: 421 ISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 480
ISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN
Sbjct: 421 ISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 480
Query: 481 MESIYEELVNPEPNTYIQINPSV 503
MESIYEELVNPEPNTYIQINPSV
Sbjct: 481 MESIYEELVNPEPNTYIQINPSV 503
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 981 bits (2537), Expect = 0.0
Identities = 491/503 (97%), Positives = 491/503 (97%), Gaps = 12/503 (2%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
Query: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN
Sbjct: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
Query: 421 ISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 480
ISQLQGRIRVEL TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN
Sbjct: 421 ISQLQGRIRVEL------------TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 468
Query: 481 MESIYEELVNPEPNTYIQINPSV 503
MESIYEELVNPEPNTYIQINPSV
Sbjct: 469 MESIYEELVNPEPNTYIQINPSV 491
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 695 bits (1794), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
Score = 337 bits (865), Expect = 1e-92
Identities = 194/303 (64%), Positives = 208/303 (68%), Gaps = 15/303 (4%)
Query: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
LS RT IH + R G Y C V N + S T+ + + ++
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
Query: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
+E + LT Q +S +W L EHL LII L G
Sbjct: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
Query: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
Y C N ARS + + + PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473
Query: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 440
ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE
Sbjct: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 533
Query: 441 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 500
ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN
Sbjct: 534 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 593
Query: 501 PSV 503
PSV
Sbjct: 594 PSV 596
Score = 102 bits (254), Expect = 8e-22
Identities = 59/184 (32%), Positives = 88/184 (47%)
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L P + S +E V C T + ++ + W + ++ E +QLS D + L I
Sbjct: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
+QR D+G Y CE + RS+P+ L + YGPD V I ES +E SS+T
Sbjct: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
+S P Y W L S H I A++ EH+G+Y C SNS T L+ ++
Sbjct: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432
Query: 247 VRVL 250
V+V+
Sbjct: 433 VKVV 436
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 695 bits (1794), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1 MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
Query: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61 HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
Score = 302 bits (774), Expect = 4e-82
Identities = 182/303 (60%), Positives = 196/303 (64%), Gaps = 27/303 (8%)
Query: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
LS RT IH + R G Y C V N + S T+ + + ++
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361
Query: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
+E + LT Q +S +W L EHL LII L G
Sbjct: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413
Query: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
Y C N ARS + + + PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473
Query: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 440
ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL
Sbjct: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL-------- 525
Query: 441 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 500
TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN
Sbjct: 526 ----TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 581
Query: 501 PSV 503
PSV
Sbjct: 582 PSV 584
Score = 102 bits (254), Expect = 8e-22
Identities = 59/184 (32%), Positives = 88/184 (47%)
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L P + S +E V C T + ++ + W + ++ E +QLS D + L I
Sbjct: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
+QR D+G Y CE + RS+P+ L + YGPD V I ES +E SS+T
Sbjct: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372
Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
+S P Y W L S H I A++ EH+G+Y C SNS T L+ ++
Sbjct: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432
Query: 247 VRVL 250
V+V+
Sbjct: 433 VKVV 436
>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 1 precursor [Homo sapiens]
Length = 526
Score = 197 bits (500), Expect = 2e-50
Identities = 123/366 (33%), Positives = 192/366 (52%), Gaps = 20/366 (5%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +N PQ + LS GAIAGIV
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434
Query: 360 IGILAVIA-VASELGYFLYIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSP 416
IG++A++A +A L FL+ R S R TE H+ S ++H +P ++
Sbjct: 435 IGVVALVALIAVALACFLHFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEV 491
Query: 417 EYCNIS 422
Y ++
Sbjct: 492 TYSTLN 497
Score = 86.3 bits (212), Expect = 6e-17
Identities = 50/127 (39%), Positives = 68/127 (53%)
Query: 54 TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
T +T + S +AKP I S T KD V C+T D I+I W N S+ ER
Sbjct: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
M+LS+ L+I V+RED+GTY CE + + +SDPI L+V Y P E L G +
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431
Query: 174 GEVVEVM 180
G V+ V+
Sbjct: 432 GIVIGVV 438
Score = 73.2 bits (178), Expect = 5e-13
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
Query: 337 PLELTI 342
P+ L +
Sbjct: 228 PVTLNV 233
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
V I + T T N + N S L I V +
Sbjct: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + V P + PS A ++ L+C N W ++G
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
+ L I + N++G Y C N
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303
Score = 30.4 bits (67), Expect = 3.9
Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A +S+ V L V P TP +SP T+Y +++
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256
Query: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
++ + SN S + + Q S + + V +SG+Y C A +++ +
Sbjct: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314
Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
+ PV K + + V + ++T + + + WF + L + R
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371
Query: 214 --------TFTIHAVSREHEGLYRCLVSN 234
T +I+ V RE G Y C V N
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400
>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
1 isoform 2 precursor [Homo sapiens]
Length = 464
Score = 191 bits (484), Expect = 2e-48
Identities = 113/319 (35%), Positives = 174/319 (54%), Gaps = 15/319 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D+G Y+CE ++ + + RSDP+ L+V YGPD I S G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W L++ +T+ I ++ + G Y C +NS T +
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314
Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
+ V E + PQ+ S + + SV+LTC T + ++++WF Q L SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374
Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
S N TL I+ ++R D G Y CEV+N S+ +S+P+ L +N PQ + LS GAIAGIV
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434
Query: 360 IGILAVIA-VASELGYFLY 377
IG++A++A +A L FL+
Sbjct: 435 IGVVALVALIAVALACFLH 453
Score = 86.3 bits (212), Expect = 6e-17
Identities = 50/127 (39%), Positives = 68/127 (53%)
Query: 54 TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
T +T + S +AKP I S T KD V C+T D I+I W N S+ ER
Sbjct: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371
Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
M+LS+ L+I V+RED+GTY CE + + +SDPI L+V Y P E L G +
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431
Query: 174 GEVVEVM 180
G V+ V+
Sbjct: 432 GIVIGVV 438
Score = 73.2 bits (178), Expect = 5e-13
Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
I V++ G Y V S ++ T + V L P + ++ N VE+ +V TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167
Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
+ Q W+++ Q L S LQLS NRTL + + RNDTGPY CE+ N S RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227
Query: 337 PLELTI 342
P+ L +
Sbjct: 228 PVTLNV 233
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL T W+PP AQLT + P + + ++V+L V P+ Q+ G S +
Sbjct: 15 WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
V I + T T N + N S L I V +
Sbjct: 72 --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E ++ W S+ LS+ RT T+ +V+R G Y C + N + S
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + V P + PS A ++ L+C N W ++G
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
+ L I + N++G Y C N
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303
Score = 30.4 bits (67), Expect = 3.9
Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A +S+ V L V P TP +SP T+Y +++
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256
Query: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
++ + SN S + + Q S + + V +SG+Y C A +++ +
Sbjct: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314
Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
+ PV K + + V + ++T + + + WF + L + R
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371
Query: 214 --------TFTIHAVSREHEGLYRCLVSN 234
T +I+ V RE G Y C V N
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400
>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
5 preproprotein [Homo sapiens]
Length = 702
Score = 156 bits (395), Expect = 4e-38
Identities = 93/278 (33%), Positives = 142/278 (51%), Gaps = 10/278 (3%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + + T W NN S+ R+QLS + LT+
Sbjct: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184
V R D+ +Y+CE ++ + ++RSD + L+V YGPD P L + SGE +
Sbjct: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244
+ S+PP Y+WF ++ +T+ I ++ + G Y C NS T L+
Sbjct: 255 LNLSCHAASNPPAQYSWF-VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313
Query: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304
+ V P + ++ N VE+ +V LTC+ Q+ W+++ Q L S LQLS
Sbjct: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373
Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
DNRTL + + RND GPY C + N S S+P+ L +
Sbjct: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411
Score = 154 bits (390), Expect = 1e-37
Identities = 99/297 (33%), Positives = 141/297 (47%), Gaps = 16/297 (5%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KP I + +E +D V C + N T W NN S+ R+QLS D + LT+
Sbjct: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D G Y+C ++ L SDP+ L+V YGPD I S G ++
Sbjct: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ S+PP Y+W + +I HT F I ++ ++ GLY C +NSA+ S
Sbjct: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492
Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305
+ V L P + ++ VE+ +V TC+ Q+ W+++GQ L S LQLS
Sbjct: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
Query: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL--------TINCPQSSSLSSGA 354
NRTL + + RND Y C + N S RS+P+ L I P SS SGA
Sbjct: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGA 609
Score = 98.2 bits (243), Expect = 2e-20
Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)
Query: 2 GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48
GP D S+ ++ G+ LS S +PPA ++ N TQ ++
Sbjct: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473
Query: 49 LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100
L + H R S EL KPSI+ + +E KD V F C + N T
Sbjct: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533
Query: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160
W N S+ R+QLS + LT+ V R D+ Y C ++++ + RSDP+ LDV YGP
Sbjct: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593
Query: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220
D + + S + G+++ + S+P Y+W ++ I T+ I +
Sbjct: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645
Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256
+ + G Y C VSN AT ++ + V + T P
Sbjct: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
Score = 67.4 bits (163), Expect = 3e-11
Identities = 47/159 (29%), Positives = 75/159 (47%), Gaps = 18/159 (11%)
Query: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262
L+ +I+ + T +T+H + + LV+ AT + RV L P + ++
Sbjct: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
VE+ +V TC+ Q W+++ Q L S LQLS NRTL + + RNDT Y
Sbjct: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213
Query: 323 ACEVWNWGSRARSEPLELTI----NCPQSSSLSSGAIAG 357
CE N S RS+ + L + + P S L++ +G
Sbjct: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG 252
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/335 (20%), Positives = 128/335 (38%), Gaps = 47/335 (14%)
Query: 3 PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
P W W +LL+ASL T W+PP A+LT+ + P + + ++V+L V P+ + G
Sbjct: 7 PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64
Query: 63 RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
S G ++ + Y I + R + + +
Sbjct: 65 YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107
Query: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181
L I+Q D+G Y + L+++ + F P P ++S V +
Sbjct: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
++ F E ++ W S+ LS+ RT T+ V+R Y+C N
Sbjct: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
+ S ++ + VL P + P + + + +++L+C N WF++G
Sbjct: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ L I + N++G Y C+ N
Sbjct: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHN 303
Score = 59.3 bits (142), Expect = 8e-09
Identities = 81/345 (23%), Positives = 141/345 (40%), Gaps = 53/345 (15%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
N L S+ V+L V P P I SP T+Y +++
Sbjct: 397 NKLSVDHSDPVILNVLYGPDDPTI--------------SPS--------YTYYRPGVNLS 434
Query: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
++ H SN S + +Q + + L I + ++SG Y C+A ++ +
Sbjct: 435 LSCHAASNPPAQYSWLIDGNIQ--QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVK 492
Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207
P + ++S V + ++ F E ++ W S+
Sbjct: 493 TITVSAELP-----KPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRL 547
Query: 208 -LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLV 266
LS+ RT T+ V+R Y C + NS + S + + VL P + P + +
Sbjct: 548 QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRS-DPVTLDVLYGPDTPIISPPDSSYL 606
Query: 267 ENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACE 325
A +++L+C + N S W ++G +P +H Q+ L I + N+ G YAC
Sbjct: 607 SGA-NLNLSCHSASNPSPQYSWRING---IPQQHTQV------LFIAKITPNNNGTYACF 656
Query: 326 VWNWGS-RARSEPLELTINCPQSS-SLSSGAIAGIVIGILAVIAV 368
V N + R S +T++ +S LS+GA GI+IG+L +A+
Sbjct: 657 VSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVAL 701
Score = 42.0 bits (97), Expect = 0.001
Identities = 66/333 (19%), Positives = 124/333 (37%), Gaps = 56/333 (16%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A +S+ V+L V P P +SP + T Y + +++N
Sbjct: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256
Query: 97 ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
++ H SN S + Q S + + V +SG+Y C+A ++ +
Sbjct: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314
Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207
Y P + + VE + ++T E ++ Y W++ +
Sbjct: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368
Query: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
LS+ RT T+ +V+R G Y C + N + + + + VL P + P S
Sbjct: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426
Query: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324
++ L+C N W + G + + L I + ++G Y C
Sbjct: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477
Query: 325 EVWNWG---SRARSEPLELTINCPQSSSLSSGA 354
+ N SR + + ++ P+ S S+ +
Sbjct: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNS 510
>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
6 (non-specific cross reacting antigen) [Homo sapiens]
Length = 344
Score = 105 bits (262), Expect = 1e-22
Identities = 60/175 (34%), Positives = 88/175 (50%), Gaps = 8/175 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
EL KPSI+ + +E KD V F C + N T W N S+ R+QLS LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V+R D+G+Y+CE ++ + RSDP+ L+V YGPD I S G ++
Sbjct: 203 LSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGPTI-------SPSKANYRPGENL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
S+PP Y+WF ++ +T+ I ++ + G Y C NSAT L+
Sbjct: 256 NLSCHAASNPPAQYSWF-INGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLN 309
Score = 72.0 bits (175), Expect = 1e-12
Identities = 78/367 (21%), Positives = 142/367 (38%), Gaps = 47/367 (12%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W +LL+ASL T W+PP A+LT+ + P + + ++V+L P+ +
Sbjct: 15 WKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQN-----------RI 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
+ G ++ ++ Y I + R + + +L I V +
Sbjct: 64 GYSWYKGERVDGNSLIVGY--------VIGTQQATPGPAYSGRETIYPNASLL-IQNVTQ 114
Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
D+G Y + + L+++ + F P P ++S V + ++ F
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167
Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
E + W S+ LS+ T T+ +V R G Y C + N A+ S
Sbjct: 168 EPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRS- 226
Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
+ + VL P + PS N +++L+C N WF++G
Sbjct: 227 DPVTLNVLYGPDGPTISPSKAN-YRPGENLNLSCHAASNPPAQYSWFING---------T 276
Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVIG 361
+ L I + N++G Y C+ N + + + + LS+ A GI IG
Sbjct: 277 FQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIG 336
Query: 362 ILAVIAV 368
+LA +A+
Sbjct: 337 VLARVAL 343
>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
16 [Homo sapiens]
Length = 484
Score = 103 bits (258), Expect = 3e-22
Identities = 71/293 (24%), Positives = 130/293 (44%), Gaps = 18/293 (6%)
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
LA+P++ + +E++D + C++ + W N ++ R+ LS DG++L
Sbjct: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
++RE++G YQCE + + RS+PI L V +GP+ V I +S +G ++V +S+T
Sbjct: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308
Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
++S P Y W L + I +++ EG Y C+ N+ T LS ++
Sbjct: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368
Query: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300
V++ +VP E + V LT Q + + V + G P+ L
Sbjct: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427
Query: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
++ N +L++ L DTG Y + + + +EL +
Sbjct: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480
Score = 83.2 bits (204), Expect = 5e-16
Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 27/194 (13%)
Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213
E + EG ++T + S AY+W+ L+ S + +HT R
Sbjct: 86 EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145
Query: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
+ I + H G Y N + +G V+V E L P V+ +S LVE
Sbjct: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
++ L C + + + V+WF +G L + L LS D R L HG++R + G Y CEVWN
Sbjct: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264
Query: 329 WGSRARSEPLELTI 342
S +RSEP+ LT+
Sbjct: 265 PVSVSRSEPINLTV 278
>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
sapiens]
Length = 426
Score = 101 bits (252), Expect = 1e-21
Identities = 81/343 (23%), Positives = 147/343 (42%), Gaps = 40/343 (11%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP A++T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQN------------- 61
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
PG + +M Y + I ++ + +++ + + L I
Sbjct: 62 ----LPGYFWYKGEMTDLY------HYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V R+D+GTY + +R D ++++ + ++ S + E
Sbjct: 112 VTRKDAGTYTLH-----IIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVR 166
Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L +Y W++ L S T RT + V++ G Y C + N +
Sbjct: 167 LICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
S + + +L L +P + ++LN EN + TC+ +++ W+L+GQ L S
Sbjct: 226 SRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPG 285
Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 286 VKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNV 328
Score = 91.7 bits (226), Expect = 1e-18
Identities = 66/213 (30%), Positives = 97/213 (45%), Gaps = 22/213 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P P I ++ E KD++ F C K N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLPI----------PYITINNLNPRENKDVLAFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ ++ + +IL + V R ++G YQCE RD RS+P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNV 328
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ T+S+PP Y W + + F
Sbjct: 329 LYGPDLPRI-------YPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLF- 380
Query: 217 IHAVSREHEGLYRCLVSNSAT--HLSSLGTLKV 247
I ++R H GLY C V NSAT +S T+KV
Sbjct: 381 IPQITRNHSGLYACSVHNSATGKEISKSMTVKV 413
Score = 71.2 bits (173), Expect = 2e-12
Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 27/272 (9%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KP I+ S E + V C + ++ + W N S+ R+QLSK + L +
Sbjct: 145 ETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R+ + + RSDP+ L++ P+ + + E +V +
Sbjct: 205 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPIPYITINNLNPRENKDV-----L 258
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 259 AFTCEPKSE-NYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYG 317
Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLLP 296
L S + + VL +P++ P S + ++DL+C T N W ++G
Sbjct: 318 GLRS-NPVILNVLYGPDLPRIYP-SFTYYRSGENLDLSCFTESNPPAEYFWTING----- 370
Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ + L I + RN +G YAC V N
Sbjct: 371 ----KFQQSGQKLFIPQITRNHSGLYACSVHN 398
>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
Length = 426
Score = 100 bits (249), Expect = 3e-21
Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + + + + L I
Sbjct: 75 LYH---------------YITSYVV--DGEIIIYGPA-------YSGRETAYSNASLLIQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V RED+G+Y + + + + + L+ P P ++S + E
Sbjct: 111 NVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLET---PKP-------SISSSNLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 TMEAVSLTCDPET---PDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + + +L L P + ++LN EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS+P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Score = 97.1 bits (240), Expect = 3e-20
Identities = 69/214 (32%), Positives = 102/214 (47%), Gaps = 22/214 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P KP I ++ E KD++ F C K N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVLNFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
YGPD P + SGEV+ + S+PP Y+W + + + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINEKFQLPGQKLF 380
Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
H ++ +H GLY C V NSAT S ++ V V
Sbjct: 381 IRH-ITTKHSGLYVCSVRNSATGKESSKSMTVEV 413
Score = 58.5 bits (140), Expect = 1e-08
Identities = 63/273 (23%), Positives = 110/273 (40%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ ++LS+ + L +
Sbjct: 145 ETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
L V + +G Y+CE R+ + + RSDP+ L++ KL + + E
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRY 316
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + + L+C N W ++ + L
Sbjct: 317 GGIRS-DPVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQL 374
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
P + L I + +G Y C V N
Sbjct: 375 PGQ---------KLFIRHITTKHSGLYVCSVRN 398
>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
[Homo sapiens]
Length = 419
Score = 100 bits (248), Expect = 4e-21
Identities = 85/343 (24%), Positives = 148/343 (43%), Gaps = 40/343 (11%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ +
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
I K +T+ IT + V + + R ++ + +L I
Sbjct: 66 ---------IWYKGQMTYLYHY----ITSYVVDGQRIIYGPAYSGRERVYSNASLL-IQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V +ED+G+Y + +R D + + ++ S + E
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166
Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L + P +Y W++ L S T RT I V++ G Y C + N +
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
S + + +L L+ P + ++LN EN + TC+ +++ W+L+GQ L S
Sbjct: 226 SRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPR 285
Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
++ +NR LI+ + RN+TGPY CE+ + RS+P+ L +
Sbjct: 286 VKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Score = 95.1 bits (235), Expect = 1e-19
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 20/213 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + +L+KP I ++ E KD++TF C K N
Sbjct: 221 NPVSASRSDPVTLNLLP------------KLSKPYITINNLNPRENKDVLTFTCEPKSKN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD L S S E ++ AE S+P Y+W ++ + + +
Sbjct: 329 LYGPD-----LPSIYPSFTYYRSGENLYLSCFAE--SNPRAQYSW-TINGKFQLSGQKLS 380
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ V+V
Sbjct: 381 IPQITTKHSGLYACSVRNSATGKESSKSITVKV 413
>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
[Homo sapiens]
Length = 419
Score = 100 bits (248), Expect = 4e-21
Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V +ED+G+Y + + + ++L+ P P ++S ++ E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + +L L P + ++L EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ L + P+ P KP I ++ E KD++ F C K N
Sbjct: 221 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328
Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
YGPD P + SGEV+ + S+PP Y+W + + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 380
Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ V+V
Sbjct: 381 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ R+QLS+ + L +
Sbjct: 145 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
L V + +G Y+CE R+ + + RSDP L++ KL + ++ E
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 257
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 316
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + + L+C N W ++G+
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 371
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398
>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
[Homo sapiens]
Length = 426
Score = 100 bits (248), Expect = 4e-21
Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110
Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
V +ED+G+Y + + + ++L+ P P ++S ++ E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160
Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
ME S+T ET P +Y W++ L S T RT + V++ G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217
Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
+ N + S + +L L P + ++L EN ++ TC+ +++ W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276
Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ L + P+ P KP I ++ E KD++ F C K N
Sbjct: 221 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328
Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
YGPD P + SGEV+ + S+PP Y+W + + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 380
Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ V+V
Sbjct: 381 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ R+QLS+ + L +
Sbjct: 145 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
L V + +G Y+CE R+ + + RSDP L++ KL + ++ E
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 257
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 316
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + + L+C N W ++G+
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 371
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398
>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
[Homo sapiens]
Length = 419
Score = 97.1 bits (240), Expect = 3e-20
Identities = 67/213 (31%), Positives = 100/213 (46%), Gaps = 20/213 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P KP I ++ E KD+ TF C K N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVSTFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ S+PP Y+W ++ + + +
Sbjct: 329 LYGPDLPRI-------YPSFTYYHSGQNLYLSCFADSNPPAQYSW-TINGKFQLSGQKLS 380
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ VRV
Sbjct: 381 IPQITTKHSGLYACSVRNSATGKESSKSVTVRV 413
Score = 96.7 bits (239), Expect = 4e-20
Identities = 88/345 (25%), Positives = 146/345 (42%), Gaps = 44/345 (12%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+ + G+ R+
Sbjct: 15 WKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L T+ + Y T++ +N S++ Q +D T+
Sbjct: 75 LYHYV------TSYIVDGQIIKYGPAYSGRETVY---SNASLLIQNVTQ--EDTGSYTLH 123
Query: 127 IVQRED-SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
I++R D +G L + P + P E E +
Sbjct: 124 IIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPR----------------EATEAVIL 167
Query: 186 TFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
T ET P +Y W++ L S T RT + V+ G Y C + N +
Sbjct: 168 TCDPET---PDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVS 224
Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPS 297
S + + +L L P + ++LN EN TC+ +++ W+L+GQ L S
Sbjct: 225 -ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVS 283
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
++ +NR LI+ + RN+TGPY CE+ + RS+P+ L +
Sbjct: 284 PRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/273 (24%), Positives = 113/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ +QLS+ + L +
Sbjct: 145 ETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSETNRTLYL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V +G Y+CE R+ + + RSDP+ L++ KL + + E +
Sbjct: 205 FGVTNYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257
Query: 186 -TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
TF E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 STFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRY 316
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + +++ L+C N W ++G+
Sbjct: 317 GGIRS-DPVTLNVLYGPDLPRIYP-SFTYYHSGQNLYLSCFADSNPPAQYSWTINGK--- 371
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 372 ----FQLS--GQKLSIPQITTKHSGLYACSVRN 398
>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
8 [Homo sapiens]
Length = 349
Score = 95.9 bits (237), Expect = 8e-20
Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ + +E KD V F C + N T W N S+ R+QLS + LT+
Sbjct: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
L V R D G Y+CE ++ + SDP+ L+V YGPD I S G ++
Sbjct: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTI-------SPSDTYYHAGVNL 255
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
S+PP Y+W + + +T + F I ++ ++ G Y C +NSAT
Sbjct: 256 NLSCHAASNPPSQYSWSVNGTFQQYTQKLF-IPNITTKNSGSYACHTTNSAT 306
Score = 82.0 bits (201), Expect = 1e-15
Identities = 90/380 (23%), Positives = 158/380 (41%), Gaps = 52/380 (13%)
Query: 3 PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
P+ W W G+LL+ASL T W+PP AQLT+ A P +A + ++V+L V P+ P+ +
Sbjct: 7 PSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYN 66
Query: 63 RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
+ G ++ + Y + IT +N ++ L ++
Sbjct: 67 WYK-----------GETVDANRRIIGYVISNQ-QITPGPAYSNRETIYPNASLLMRN--- 111
Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
V R D+G+Y + L+ S+ + P+ + + S + VE +
Sbjct: 112 -----VTRNDTGSYTLQV--IKLNLMSEEVTGQFSVHPETPKPSISSN--NSNPVEDKDA 162
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
+ T ET++ Y W++ LS+ RT T+ +V+R G Y C + N
Sbjct: 163 VAFTCEPETQN---TTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
A+ S + + VL P + PS +++L+C N W ++G
Sbjct: 220 PASANFS-DPVTLNVLYGPDAPTISPSD-TYYHAGVNLNLSCHAASNPPSQYSWSVNG-- 275
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP----QSS 348
+ L I + ++G YAC N + R R+ +T++ S
Sbjct: 276 -------TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSP 328
Query: 349 SLSSGAIAGIVIGILAVIAV 368
LS+ A I+IG+LA +A+
Sbjct: 329 GLSARATVSIMIGVLARVAL 348
>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
sapiens]
Length = 428
Score = 95.9 bits (237), Expect = 8e-20
Identities = 89/348 (25%), Positives = 150/348 (43%), Gaps = 50/348 (14%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+A L W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ-------------- 60
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
++A + KD+ + IT + V + + + R + + +L I
Sbjct: 61 NLAGYIWYKGQMKDLYHY--------ITSYVVDGQIIIYGPAYSGRETVYSNASLL-IQN 111
Query: 128 VQREDSGTYQC---EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--EVMEG 182
V RED+G+Y + D + F P P ++S + E ME
Sbjct: 112 VTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKP-------SISSSNLYPREDMEA 164
Query: 183 SSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSN 234
S+T ET P +Y W++ L S RT + V++ G Y C + N
Sbjct: 165 VSLTCDPET---PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRN 221
Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPL 294
+ S + + +L L P + ++LN EN + TC+ +++ W+L+GQ L
Sbjct: 222 PVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSL 280
Query: 295 LPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 281 PVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNV 328
Score = 91.7 bits (226), Expect = 1e-18
Identities = 64/213 (30%), Positives = 98/213 (46%), Gaps = 20/213 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P KP I ++ E KD++ F C K N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVLAFTCEPKSEN 268
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE +D RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNV 328
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ S+PP Y+W + + F
Sbjct: 329 LYGPDLPRI-------YPSFTYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLF- 380
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT + S ++ V+V
Sbjct: 381 IPQITTKHSGLYACSVRNSATGMESSKSMTVKV 413
Score = 62.8 bits (151), Expect = 7e-10
Identities = 67/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ +QLSK+ + L +
Sbjct: 145 ETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLQLSKNKRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
V + +G Y+CE R+ + + RSDP+ L++ KL + + E
Sbjct: 205 FGVTKYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 LAFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRY 316
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + ++ L+C N W ++G+
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYHSGENLYLSCFADSNPPAEYSWTINGK--- 371
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 93.6 bits (231), Expect = 4e-19
Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 21/228 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P P I ++ E+KD++ F C K N
Sbjct: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS+P+ L+V
Sbjct: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ S+PP Y+W + + F
Sbjct: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379
Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLN 264
I ++ H GLY C V NSAT ++ V+V ET + PQV + N
Sbjct: 380 IPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETAS-PQVTYAGPN 426
Score = 91.3 bits (225), Expect = 2e-18
Identities = 89/349 (25%), Positives = 145/349 (41%), Gaps = 53/349 (15%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+ + A P ++ +DV+L V P+ +
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
I K +T Y T+ V+ I + + R + + +L I
Sbjct: 66 ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
V +ED+G+Y + +R D F Y P S + EV+E +
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
L P +Y W L L S T RT + V++ G Y C +
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
N + S + + +L L MP + ++LN E + TC+ +++ W+L+GQ
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
Score = 70.1 bits (170), Expect = 4e-12
Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 27/272 (9%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W+ N ++ R+QLSK + L +
Sbjct: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R+ + + RSDP+ L++ P+ + + E +V +
Sbjct: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPMPYITINNLNPREKKDV-----L 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 AFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYG 316
Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLP 296
+ S + + VL +P++ P S + ++DL+C N W ++G+
Sbjct: 317 GIRS-NPVTLNVLYGPDLPRIYP-SFTYYRSGENLDLSCFADSNPPAEYSWTINGK---- 370
Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + N +G YAC V N
Sbjct: 371 ---FQLS--GQKLFIPQITTNHSGLYACSVRN 397
>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 92.8 bits (229), Expect = 6e-19
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
+L KP I ++ E KD++ F C K N T W N S+ R++ + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V R ++G Y+CE RD RSDP+ L+V YGPD L S S E +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+PP Y W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
Query: 246 KVRV 249
V V
Sbjct: 317 TVEV 320
Score = 59.7 bits (143), Expect = 6e-09
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 1/134 (0%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V+RE G Y + + G + L P + ++ EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ TC+ +++ W+L+GQ L S ++ +NR LI+ + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 329 WGSRARSEPLELTI 342
RS+P+ L +
Sbjct: 222 RDGGMRSDPVTLNV 235
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/346 (21%), Positives = 128/346 (36%), Gaps = 48/346 (13%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
G ++ +T Y +NI + R + + +L I V R
Sbjct: 64 GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114
Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
ED+G+Y + +R D Y + +KL + + E + F
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169
Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
E KS Y W+L L + R + +V+R G Y C + + + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228
Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
+ + VL +P + P S + ++ L+C N W ++G
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP 345
+ + L I + G Y C V N + + S+ + + ++ P
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323
>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
sapiens]
Length = 335
Score = 92.8 bits (229), Expect = 6e-19
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
+L KP I ++ E KD++ F C K N T W N S+ R++ + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V R ++G Y+CE RD RSDP+ L+V YGPD L S S E +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+PP Y W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316
Query: 246 KVRV 249
V V
Sbjct: 317 TVEV 320
Score = 59.7 bits (143), Expect = 6e-09
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 1/134 (0%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
++ + I V+RE G Y + + G + L P + ++ EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161
Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
+ TC+ +++ W+L+GQ L S ++ +NR LI+ + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221
Query: 329 WGSRARSEPLELTI 342
RS+P+ L +
Sbjct: 222 RDGGMRSDPVTLNV 235
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/346 (21%), Positives = 128/346 (36%), Gaps = 48/346 (13%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
G ++ +T Y +NI + R + + +L I V R
Sbjct: 64 GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114
Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
ED+G+Y + +R D Y + +KL + + E + F
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169
Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
E KS Y W+L L + R + +V+R G Y C + + + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228
Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
+ + VL +P + P S + ++ L+C N W ++G
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277
Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP 345
+ + L I + G Y C V N + + S+ + + ++ P
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 91.3 bits (225), Expect = 2e-18
Identities = 89/349 (25%), Positives = 145/349 (41%), Gaps = 53/349 (15%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+ P AQ+ + A P ++ +DV+L V P+ +
Sbjct: 15 WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65
Query: 71 SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
I K +T Y T+ V+ I + + R + + +L I
Sbjct: 66 ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110
Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
V +ED+G+Y + +R D F Y P S + EV+E +
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165
Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
L P +Y W L L S T RT + V++ G Y C +
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219
Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
N + S + + +L L MP + ++LN E + TC+ +++ W+L+GQ
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278
Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
Score = 88.6 bits (218), Expect = 1e-17
Identities = 61/201 (30%), Positives = 91/201 (45%), Gaps = 20/201 (9%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ V L + P+ P P I ++ E+KD++ F C K N
Sbjct: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS+P+ L+V
Sbjct: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327
Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
YGPD I G ++ S+PP Y+W + + F
Sbjct: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379
Query: 217 IHAVSREHEGLYRCLVSNSAT 237
I ++ H GLY C V NSAT
Sbjct: 380 IPQITTNHSGLYACSVRNSAT 400
Score = 70.1 bits (170), Expect = 4e-12
Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 27/272 (9%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W+ N ++ R+QLSK + L +
Sbjct: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R+ + + RSDP+ L++ P+ + + E +V +
Sbjct: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPMPYITINNLNPREKKDV-----L 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 258 AFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYG 316
Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLP 296
+ S + + VL +P++ P S + ++DL+C N W ++G+
Sbjct: 317 GIRS-NPVTLNVLYGPDLPRIYP-SFTYYRSGENLDLSCFADSNPPAEYSWTINGK---- 370
Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + N +G YAC V N
Sbjct: 371 ---FQLS--GQKLFIPQITTNHSGLYACSVRN 397
>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
[Homo sapiens]
Length = 297
Score = 90.9 bits (224), Expect = 2e-18
Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)
Query: 37 NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
NP+ A++S+ L + P+ P KP I ++ E KD++ F C K N
Sbjct: 99 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 146
Query: 97 ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
T W N S+ R++ + +IL + V R ++G YQCE RD RS P+ L+V
Sbjct: 147 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 206
Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
YGPD P + SGEV+ + S+PP Y+W + + F
Sbjct: 207 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 258
Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
I ++ +H GLY C V NSAT S ++ V+V
Sbjct: 259 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 291
Score = 77.8 bits (190), Expect = 2e-14
Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 12/173 (6%)
Query: 178 EVMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYR 229
E ME S+T ET P +Y W++ L S T RT + V++ G Y
Sbjct: 38 EAMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYE 94
Query: 230 CLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFL 289
C + N + S + +L L P + ++L EN ++ TC+ +++ W+L
Sbjct: 95 CEIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWL 153
Query: 290 SGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
+GQ L S ++ +NR LI+ + RN+TGPY CE+ + RS P+ L +
Sbjct: 154 NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 206
Score = 66.2 bits (160), Expect = 6e-11
Identities = 34/87 (39%), Positives = 47/87 (54%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S LN E +V LTC + W+++GQ L S LQLS NRTL + G+
Sbjct: 27 PSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
+ GPY CE+ N S +RS+P L +
Sbjct: 87 KYTAGPYECEIRNPVSASRSDPFTLNL 113
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V+ C + + + W N S+ R+QLS+ + L +
Sbjct: 23 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
L V + +G Y+CE R+ + + RSDP L++ KL + ++ E
Sbjct: 83 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 135
Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
+ F E KS Y W+L L + R + +V+R G Y+C + +
Sbjct: 136 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 194
Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
+ S + + VL +P++ P S + + L+C N W ++G+
Sbjct: 195 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 249
Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 250 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 276
>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
7 [Homo sapiens]
Length = 265
Score = 85.5 bits (210), Expect = 1e-16
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 4/117 (3%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + ++ N VEN V LTCQ Q+ W+++ Q LL S L LS DNRTL++
Sbjct: 148 PSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSAT 207
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINC----PQSSSLSSGAIAGIVIGILAVIAV 368
+ND GPY CE+ N +RS+P+ L + S LS+G I+IG+LA +A+
Sbjct: 208 KNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMAL 264
Score = 70.1 bits (170), Expect = 4e-12
Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 11/126 (8%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI + +E KD+V C + N T W NN S++ R+ LS D + L +
Sbjct: 144 EPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVL 203
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKY------GPDPVEIKLESGVASGEVVEV 179
L + D G Y+CE ++ + + RSDP+ L+V+Y PD L +G A ++ V
Sbjct: 204 LSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPD-----LSAGTAVSIMIGV 258
Query: 180 MEGSSM 185
+ G ++
Sbjct: 259 LAGMAL 264
Score = 39.3 bits (90), Expect = 0.008
Identities = 16/41 (39%), Positives = 27/41 (65%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPV 51
W G+LL+ASL T W+ P +AQ ++ P + + ++V+L V
Sbjct: 15 WQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVV 55
>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
sapiens]
Length = 335
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/184 (28%), Positives = 85/184 (46%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ R QLS+ + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R++ + RSDP+ L++ +GPD I G ++
Sbjct: 205 FGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRI-------HPSYTNYRSGDNL 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W ++ + + I ++ +H GLY C V NSAT S +L
Sbjct: 258 YLSCFANSNPPAQYSW-TINGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSL 316
Query: 246 KVRV 249
V+V
Sbjct: 317 TVKV 320
Score = 72.4 bits (176), Expect = 9e-13
Identities = 45/140 (32%), Positives = 68/140 (48%), Gaps = 11/140 (7%)
Query: 209 SHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSS 262
+++ + I V+RE G Y + GT V T T+ P + S+
Sbjct: 101 AYSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSN 155
Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
LN E +V LTC + QW+++GQ L + QLS NRTL + G+ + GPY
Sbjct: 156 LNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPY 215
Query: 323 ACEVWNWGSRARSEPLELTI 342
CE+ N GS +RS+P+ L +
Sbjct: 216 ECEIRNSGSASRSDPVTLNL 235
Score = 59.7 bits (143), Expect = 6e-09
Identities = 83/369 (22%), Positives = 139/369 (37%), Gaps = 64/369 (17%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
W G+L++ASL W+ P AQ+T+ A P ++ +DV+L V P+ G+ R+
Sbjct: 15 WKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + + + + L I
Sbjct: 75 L---------------YHYITSYVV--DGQIIIYGPA-------YSGRETAYSNASLLIQ 110
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
V RED+G+Y + +R D Y + ++ S + E
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165
Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
L P +Y W++ LS T RT + V++ G Y C + NS +
Sbjct: 166 ILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGS- 224
Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
S + + +L +P++ PS N + ++ L+C N W ++G+
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIHPSYTN-YRSGDNLYLSCFANSNPPAQYSWTINGK----- 278
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAG 357
Q S N L I + +G Y C V N + S S+SL+ A
Sbjct: 279 --FQQSGQN--LFIPQITTKHSGLYVCSVRNSATGEES-----------STSLTVKVSAS 323
Query: 358 IVIGILAVI 366
IG+L ++
Sbjct: 324 TRIGLLPLL 332
>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 81.6 bits (200), Expect = 1e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194
Query: 246 KVRVL 250
+RV+
Sbjct: 195 TIRVI 199
Score = 73.9 bits (180), Expect = 3e-13
Identities = 34/87 (39%), Positives = 51/87 (58%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + W+++GQ L + +QLS NRTL + G+
Sbjct: 27 PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
+ GPY CE+WN GS +RS+P+ L +
Sbjct: 87 KYTAGPYECEIWNSGSASRSDPVTLNL 113
>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
[Homo sapiens]
Length = 213
Score = 81.6 bits (200), Expect = 1e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 23 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 83 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194
Query: 246 KVRVL 250
+RV+
Sbjct: 195 TIRVI 199
Score = 73.9 bits (180), Expect = 3e-13
Identities = 34/87 (39%), Positives = 51/87 (58%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + W+++GQ L + +QLS NRTL + G+
Sbjct: 27 PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
+ GPY CE+WN GS +RS+P+ L +
Sbjct: 87 KYTAGPYECEIWNSGSASRSDPVTLNL 113
>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
[Homo sapiens]
Length = 335
Score = 81.6 bits (200), Expect = 1e-15
Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + + + W N S+ RMQLS+ + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE ++ + RSDP+ L++ +GPD I V G ++
Sbjct: 205 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 257
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
S+PP Y+W + + F I ++ +H GLY C NSAT S +L
Sbjct: 258 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 316
Query: 246 KVRVL 250
+RV+
Sbjct: 317 TIRVI 321
Score = 75.5 bits (184), Expect = 1e-13
Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 11/139 (7%)
Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSSL 263
++ + I V+RE G Y + GT V T T+ P + S+L
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSNL 156
Query: 264 NLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
N E +V LTC + W+++GQ L + +QLS NRTL + G+ + GPY
Sbjct: 157 NPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYE 216
Query: 324 CEVWNWGSRARSEPLELTI 342
CE+WN GS +RS+P+ L +
Sbjct: 217 CEIWNSGSASRSDPVTLNL 235
Score = 56.6 bits (135), Expect = 5e-08
Identities = 75/331 (22%), Positives = 125/331 (37%), Gaps = 53/331 (16%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
W G+LL+A L W+ P AQ+ + A P ++ +DV+L V P+ G+ R+
Sbjct: 15 WKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74
Query: 67 LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
L +T Y D I I+ + R + + +L I
Sbjct: 75 L---------------YHYITSYVV--DGQIIIY------GPAYSGRETVYSNASLL-IQ 110
Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
V RED+G+Y + +R D Y + ++ S + E
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165
Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
L P +Y W++ LS T RT + V++ G Y C + NS +
Sbjct: 166 ILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGS- 224
Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
S + + +L +P++ P S+ + ++DL+C N W ++G+
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIFP-SVTSYYSGENLDLSCFANSNPPAQYSWTINGK----- 278
Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + G YAC N
Sbjct: 279 --FQLS--GQKLFIPQITPKHNGLYACSARN 305
>gi|148612793 carcinoembryonic antigen-related cell adhesion
molecule isoform 1 [Homo sapiens]
Length = 293
Score = 81.3 bits (199), Expect = 2e-15
Identities = 62/196 (31%), Positives = 93/196 (47%), Gaps = 14/196 (7%)
Query: 220 VSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV 279
V+ E G Y V+ + + + +RV E++ P + SS + E SV LTC T
Sbjct: 112 VTLEDTGYYNLQVTYRNSQIEQ-ASHHLRVYESVAQPSIQASSTTVTEKG-SVVLTCHTN 169
Query: 280 NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
N + QW + Q L ++ ++LS N L I +++ D G Y CEV N S RS+PL+
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229
Query: 340 LTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 399
LT+ +S + G + G+++G L V A+ FL +R R S D S Q
Sbjct: 230 LTV---KSDDNTLGILIGVLVGSLLVAALVC----FLLLRKTGRAS-----DQSDFREQQ 277
Query: 400 IPKEEHPTEPSSESLS 415
P PS S+S
Sbjct: 278 PPASTPGHGPSDSSIS 293
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 54 TPRTPQIHGRSREL------AKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLS 107
T R QI S L A+PSI S T + +K V C T + + W+ NN
Sbjct: 125 TYRNSQIEQASHHLRVYESVAQPSIQAS-STTVTEKGSVVLTCHTNNTGTSFQWIFNNQR 183
Query: 108 VVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKL 167
+ +RM+LS +LTI +++ED+G YQCE + + S RSDP+ L VK + + I +
Sbjct: 184 LQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLGILI 243
Query: 168 ESGVASGEVV 177
GV G ++
Sbjct: 244 --GVLVGSLL 251
Score = 48.9 bits (115), Expect = 1e-05
Identities = 57/248 (22%), Positives = 90/248 (36%), Gaps = 44/248 (17%)
Query: 1 MGPADSWGHH----WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPR 56
MGP + H W G+LL+ASL T W+ P A L + + P + + E+V L V P
Sbjct: 1 MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60
Query: 57 TPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQL 116
+G + G +E ++ Y V + R +
Sbjct: 61 NLYSYGWYK-----------GKTVEPNQLIAAYVIDTHVRTP--------GPAYSGRETI 101
Query: 117 SKDGKILTILIVQREDSGTY--QCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
S G L V ED+G Y Q R++ + Q S + + ++ + G
Sbjct: 102 SPSGD-LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKG 160
Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR--------TFTIHAVSREHEG 226
VV L ++ ++ W + L T R TI + +E G
Sbjct: 161 SVV----------LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAG 210
Query: 227 LYRCLVSN 234
Y+C VSN
Sbjct: 211 EYQCEVSN 218
>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
[Homo sapiens]
Length = 326
Score = 79.7 bits (195), Expect = 6e-15
Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 8/184 (4%)
Query: 66 ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
E KPSI+ S E + V C + W N S+ R+QLSK + L I
Sbjct: 145 ETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFI 204
Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
V + +G Y+CE R+ + + RSDP+ L++ +GPD L S S E +
Sbjct: 205 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD-----LPSIYPSFTYYRSGENLYL 259
Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
+ AE S+P Y+W ++ + + +I ++ +H GLY C V NSAT S ++
Sbjct: 260 SCFAE--SNPRAQYSW-TINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSI 316
Query: 246 KVRV 249
V+V
Sbjct: 317 TVKV 320
Score = 69.3 bits (168), Expect = 8e-12
Identities = 35/87 (40%), Positives = 51/87 (58%)
Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
P + S+LN E +V LTC + + QW+++GQ L + LQLS NRTL I G+
Sbjct: 149 PSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVT 208
Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
+ GPY CE+ N S +RS+P+ L +
Sbjct: 209 KYIAGPYECEIRNPVSASRSDPVTLNL 235
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/330 (21%), Positives = 125/330 (37%), Gaps = 51/330 (15%)
Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
W G+LL+ASL W+PP AQ+T+ A P ++ +DV+L V P+
Sbjct: 15 WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ-------------- 60
Query: 71 SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
+ I K +T+ + +V + +++ + + L I
Sbjct: 61 ----NLAGYIWYKGQMTYL-----YHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQN 111
Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
V +ED+G+Y + +R D + + ++ S + E
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166
Query: 188 LAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
L + P +Y W++ LS T RT I V++ G Y C + N +
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225
Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSE 298
S + + +L +P + P S + ++ L+C N W ++G+
Sbjct: 226 SRSDPVTLNLLHGPDLPSIYP-SFTYYRSGENLYLSCFAESNPRAQYSWTINGK------ 278
Query: 299 HLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
QLS + L I + +G YAC V N
Sbjct: 279 -FQLS--GQKLSIPQITTKHSGLYACSVRN 305
>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
isoform 2 [Homo sapiens]
Length = 292
Score = 79.3 bits (194), Expect = 7e-15
Identities = 61/196 (31%), Positives = 90/196 (45%), Gaps = 15/196 (7%)
Query: 220 VSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV 279
V+ E G Y V+ + + + +RV E++ P + SS + E SV LTC T
Sbjct: 112 VTLEDTGYYNLQVTYRNSQIEQ-ASHHLRVYESVAQPSIQASSTTVTEKG-SVVLTCHTN 169
Query: 280 NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
N + QW + Q L ++ ++LS N L I +++ D G Y CEV N S RS+PL+
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229
Query: 340 LTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 399
LT+ + GI+IG+L + + L FL +R R S D S Q
Sbjct: 230 LTVKYDNT--------LGILIGVLVGSLLVAALVCFLLLRKTGRAS-----DQSDFREQQ 276
Query: 400 IPKEEHPTEPSSESLS 415
P PS S+S
Sbjct: 277 PPASTPGHGPSDSSIS 292
Score = 70.1 bits (170), Expect = 4e-12
Identities = 42/111 (37%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 54 TPRTPQIHGRSREL------AKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLS 107
T R QI S L A+PSI S T + +K V C T + + W+ NN
Sbjct: 125 TYRNSQIEQASHHLRVYESVAQPSIQAS-STTVTEKGSVVLTCHTNNTGTSFQWIFNNQR 183
Query: 108 VVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
+ +RM+LS +LTI +++ED+G YQCE + + S RSDP+ L VKY
Sbjct: 184 LQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234
Score = 48.9 bits (115), Expect = 1e-05
Identities = 57/248 (22%), Positives = 90/248 (36%), Gaps = 44/248 (17%)
Query: 1 MGPADSWGHH----WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPR 56
MGP + H W G+LL+ASL T W+ P A L + + P + + E+V L V P
Sbjct: 1 MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60
Query: 57 TPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQL 116
+G + G +E ++ Y V + R +
Sbjct: 61 NLYSYGWYK-----------GKTVEPNQLIAAYVIDTHVRTP--------GPAYSGRETI 101
Query: 117 SKDGKILTILIVQREDSGTY--QCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
S G L V ED+G Y Q R++ + Q S + + ++ + G
Sbjct: 102 SPSGD-LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKG 160
Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR--------TFTIHAVSREHEG 226
VV L ++ ++ W + L T R TI + +E G
Sbjct: 161 SVV----------LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAG 210
Query: 227 LYRCLVSN 234
Y+C VSN
Sbjct: 211 EYQCEVSN 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,319,500
Number of Sequences: 37866
Number of extensions: 1051646
Number of successful extensions: 7316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 5145
Number of HSP's gapped (non-prelim): 1687
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.