Guide to the Human Genome
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Search of human proteins with 156564388

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
         (491 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156564388 carcinoembryonic antigen-related cell adhesion mole...   990   0.0  
gi|156564390 carcinoembryonic antigen-related cell adhesion mole...   981   0.0  
gi|156564378 carcinoembryonic antigen-related cell adhesion mole...   695   0.0  
gi|156564393 carcinoembryonic antigen-related cell adhesion mole...   695   0.0  
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...   197   2e-50
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...   191   2e-48
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...   156   4e-38
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...   105   9e-23
gi|85861202 carcinoembryonic antigen-related cell adhesion molec...   103   3e-22
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi...   101   1e-21
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]   100   3e-21
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [...   100   4e-21
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ...   100   4e-21
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [...   100   4e-21
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ...    97   3e-20
gi|21314600 carcinoembryonic antigen-related cell adhesion molec...    96   7e-20
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi...    96   7e-20
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H...    94   4e-19
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...    93   6e-19
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...    93   6e-19
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [...    91   2e-18
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ...    91   2e-18
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu...    86   1e-16
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi...    82   1e-15
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2...    82   1e-15
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2...    82   1e-15
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1...    82   1e-15
gi|148612793 carcinoembryonic antigen-related cell adhesion mole...    81   2e-15
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [...    80   5e-15
gi|52317156 carcinoembryonic antigen-related cell adhesion molec...    79   7e-15

>gi|156564388 carcinoembryonic antigen-related cell adhesion
           molecule 20 4S [Homo sapiens]
          Length = 491

 Score =  990 bits (2560), Expect = 0.0
 Identities = 491/491 (100%), Positives = 491/491 (100%)

Query: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
           MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60

Query: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
           HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120

Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
           KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180

Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
           EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240

Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
           SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
           QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360

Query: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
           GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN
Sbjct: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420

Query: 421 ISQLQGRIRVELTKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPE 480
           ISQLQGRIRVELTKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPE
Sbjct: 421 ISQLQGRIRVELTKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPE 480

Query: 481 PNTYIQINPSV 491
           PNTYIQINPSV
Sbjct: 481 PNTYIQINPSV 491


>gi|156564390 carcinoembryonic antigen-related cell adhesion
           molecule 20 4L [Homo sapiens]
          Length = 503

 Score =  981 bits (2537), Expect = 0.0
 Identities = 491/503 (97%), Positives = 491/503 (97%), Gaps = 12/503 (2%)

Query: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
           MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60

Query: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
           HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120

Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
           KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180

Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
           EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240

Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
           SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360
           QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVI 360

Query: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420
           GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN
Sbjct: 361 GILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCN 420

Query: 421 ISQLQGRIRVEL------------TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 468
           ISQLQGRIRVEL            TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN
Sbjct: 421 ISQLQGRIRVELMQPPDLPEETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKN 480

Query: 469 MESIYEELVNPEPNTYIQINPSV 491
           MESIYEELVNPEPNTYIQINPSV
Sbjct: 481 MESIYEELVNPEPNTYIQINPSV 503


>gi|156564378 carcinoembryonic antigen-related cell adhesion
           molecule 20 5L [Homo sapiens]
          Length = 596

 Score =  695 bits (1794), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
           MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60

Query: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
           HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120

Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
           KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180

Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
           EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240

Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
           SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
           QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343



 Score =  302 bits (774), Expect = 4e-82
 Identities = 182/303 (60%), Positives = 196/303 (64%), Gaps = 27/303 (8%)

Query: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
           LS   RT  IH + R   G Y C V N  +   S     T+     +     +     ++
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361

Query: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
            +E   +  LT Q   +S      +W L        EHL        LII  L     G 
Sbjct: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413

Query: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
           Y C   N     ARS  + + +  PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473

Query: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL-------- 432
           ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVEL        
Sbjct: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELMQPPDLPE 533

Query: 433 ----TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 488
               TKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN
Sbjct: 534 ETYETKLPSASRRGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQIN 593

Query: 489 PSV 491
           PSV
Sbjct: 594 PSV 596



 Score =  102 bits (254), Expect = 8e-22
 Identities = 59/184 (32%), Positives = 88/184 (47%)

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L  P +  S    +E    V   C T + ++ + W  +   ++  E +QLS D + L I 
Sbjct: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312

Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
            +QR D+G Y CE  +     RS+P+ L + YGPD V I  ES       +E    SS+T
Sbjct: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372

Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
                +S P   Y W L  S   H      I A++ EH+G+Y C  SNS T L+   ++ 
Sbjct: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432

Query: 247 VRVL 250
           V+V+
Sbjct: 433 VKVV 436


>gi|156564393 carcinoembryonic antigen-related cell adhesion
           molecule 20 5S [Homo sapiens]
          Length = 584

 Score =  695 bits (1794), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60
           MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI
Sbjct: 1   MGPADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQI 60

Query: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120
           HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG
Sbjct: 61  HGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDG 120

Query: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180
           KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM
Sbjct: 121 KILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVM 180

Query: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
           EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS
Sbjct: 181 EGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240

Query: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300
           SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL
Sbjct: 241 SLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL 300

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343
           QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN
Sbjct: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN 343



 Score =  311 bits (797), Expect = 9e-85
 Identities = 182/291 (62%), Positives = 196/291 (67%), Gaps = 15/291 (5%)

Query: 208 LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLG---TLKVRVLETLTMPQVVPSSLN 264
           LS   RT  IH + R   G Y C V N  +   S     T+     +     +     ++
Sbjct: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMIS 361

Query: 265 LVENARSVDLTCQTVNQS---VNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGP 321
            +E   +  LT Q   +S      +W L        EHL        LII  L     G 
Sbjct: 362 TIEAELNSSLTLQCWAESKPGAEYRWTLEHST---GEHL-----GEQLIIRALTWEHDGI 413

Query: 322 YACEVWN-WGSRARSEPLELTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 380
           Y C   N     ARS  + + +  PQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN
Sbjct: 414 YNCTASNSLTGLARSTSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRN 473

Query: 381 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELTKLPSASR 440
           ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELTKLPSASR
Sbjct: 474 ARRPSRKTTEDPSHETSQPIPKEEHPTEPSSESLSPEYCNISQLQGRIRVELTKLPSASR 533

Query: 441 RGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 491
           RGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV
Sbjct: 534 RGNSFSPWKPPPKPLMPPLRLVSTVPKNMESIYEELVNPEPNTYIQINPSV 584



 Score =  102 bits (254), Expect = 8e-22
 Identities = 59/184 (32%), Positives = 88/184 (47%)

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L  P +  S    +E    V   C T + ++ + W  +   ++  E +QLS D + L I 
Sbjct: 253 LTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIH 312

Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
            +QR D+G Y CE  +     RS+P+ L + YGPD V I  ES       +E    SS+T
Sbjct: 313 GLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLT 372

Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
                +S P   Y W L  S   H      I A++ EH+G+Y C  SNS T L+   ++ 
Sbjct: 373 LQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVL 432

Query: 247 VRVL 250
           V+V+
Sbjct: 433 VKVV 436


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score =  197 bits (500), Expect = 2e-50
 Identities = 123/366 (33%), Positives = 192/366 (52%), Gaps = 20/366 (5%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           L V R D+G Y+CE ++ + + RSDP+ L+V YGPD   I       S        G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +      S+PP  Y+W L++     +T+   I  ++  + G Y C  +NS T  +     
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314

Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
            + V E    +  PQ+  S   +  +  SV+LTC T +  ++++WF   Q L  SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374

Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
           S  N TL I+ ++R D G Y CEV+N  S+ +S+P+ L +N    PQ + LS GAIAGIV
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434

Query: 360 IGILAVIA-VASELGYFLYIRNARRPS--RKTTEDPSHETSQPIPKEEHPTEPSSESLSP 416
           IG++A++A +A  L  FL+     R S  R  TE   H+ S     ++H  +P ++    
Sbjct: 435 IGVVALVALIAVALACFLHFGKTGRASDQRDLTE---HKPSVSNHTQDHSNDPPNKMNEV 491

Query: 417 EYCNIS 422
            Y  ++
Sbjct: 492 TYSTLN 497



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 50/127 (39%), Positives = 68/127 (53%)

Query: 54  TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
           T +T  +   S  +AKP I  S  T    KD V   C+T D  I+I W   N S+   ER
Sbjct: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371

Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
           M+LS+    L+I  V+RED+GTY CE  + +   +SDPI L+V Y   P E  L  G  +
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431

Query: 174 GEVVEVM 180
           G V+ V+
Sbjct: 432 GIVIGVV 438



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
           I  V++   G Y   V  S   ++   T +  V   L  P +  ++ N VE+  +V  TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167

Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
           +   Q     W+++ Q L  S  LQLS  NRTL +  + RNDTGPY CE+ N  S  RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227

Query: 337 PLELTI 342
           P+ L +
Sbjct: 228 PVTLNV 233



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL T W+PP  AQLT  + P +  + ++V+L V   P+  Q+ G S    + 
Sbjct: 15  WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
              V     I    + T   T    N     +  N S               L I  V +
Sbjct: 72  --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114

Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
            D+G Y  +  +  L+++ +   F      P P        ++S     V +  ++ F  
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167

Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
           E ++       W    S+       LS+  RT T+ +V+R   G Y C + N  +   S 
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226

Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
             + + V      P + PS       A ++ L+C    N      W ++G          
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276

Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
                + L I  +  N++G Y C   N
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A +S+ V L V   P TP               +SP          T+Y    +++
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256

Query: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
           ++ +  SN     S + +   Q S     +  + V   +SG+Y C A +++       + 
Sbjct: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314

Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
             +     PV  K +   +   V    +  ++T    + +    +  WF  +  L  + R
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371

Query: 214 --------TFTIHAVSREHEGLYRCLVSN 234
                   T +I+ V RE  G Y C V N
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score =  191 bits (484), Expect = 2e-48
 Identities = 113/319 (35%), Positives = 174/319 (54%), Gaps = 15/319 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTL 202

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           L V R D+G Y+CE ++ + + RSDP+ L+V YGPD   I       S        G+++
Sbjct: 203 LSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTI-------SPSDTYYRPGANL 255

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +      S+PP  Y+W L++     +T+   I  ++  + G Y C  +NS T  +     
Sbjct: 256 SLSCYAASNPPAQYSW-LINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVK 314

Query: 246 KVRVLE---TLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQL 302
            + V E    +  PQ+  S   +  +  SV+LTC T +  ++++WF   Q L  SE ++L
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKL 374

Query: 303 SADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTIN---CPQSSSLSSGAIAGIV 359
           S  N TL I+ ++R D G Y CEV+N  S+ +S+P+ L +N    PQ + LS GAIAGIV
Sbjct: 375 SQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIV 434

Query: 360 IGILAVIA-VASELGYFLY 377
           IG++A++A +A  L  FL+
Sbjct: 435 IGVVALVALIAVALACFLH 453



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 50/127 (39%), Positives = 68/127 (53%)

Query: 54  TPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHER 113
           T +T  +   S  +AKP I  S  T    KD V   C+T D  I+I W   N S+   ER
Sbjct: 312 TVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSER 371

Query: 114 MQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVAS 173
           M+LS+    L+I  V+RED+GTY CE  + +   +SDPI L+V Y   P E  L  G  +
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIA 431

Query: 174 GEVVEVM 180
           G V+ V+
Sbjct: 432 GIVIGVV 438



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 44/126 (34%), Positives = 64/126 (50%), Gaps = 1/126 (0%)

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC 276
           I  V++   G Y   V  S   ++   T +  V   L  P +  ++ N VE+  +V  TC
Sbjct: 109 IQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTC 167

Query: 277 QTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSE 336
           +   Q     W+++ Q L  S  LQLS  NRTL +  + RNDTGPY CE+ N  S  RS+
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSD 227

Query: 337 PLELTI 342
           P+ L +
Sbjct: 228 PVTLNV 233



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 47/327 (14%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL T W+PP  AQLT  + P +  + ++V+L V   P+  Q+ G S    + 
Sbjct: 15  WQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQ--QLFGYSWYKGE- 71

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
              V     I    + T   T    N     +  N S               L I  V +
Sbjct: 72  --RVDGNRQIVGYAIGTQQATPGPANSGRETIYPNAS---------------LLIQNVTQ 114

Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
            D+G Y  +  +  L+++ +   F      P P        ++S     V +  ++ F  
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167

Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
           E ++       W    S+       LS+  RT T+ +V+R   G Y C + N  +   S 
Sbjct: 168 EPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRS- 226

Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
             + + V      P + PS       A ++ L+C    N      W ++G          
Sbjct: 227 DPVTLNVTYGPDTPTISPSDTYYRPGA-NLSLSCYAASNPPAQYSWLING---------T 276

Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWN 328
                + L I  +  N++G Y C   N
Sbjct: 277 FQQSTQELFIPNITVNNSGSYTCHANN 303



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 44/209 (21%), Positives = 78/209 (37%), Gaps = 38/209 (18%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A +S+ V L V   P TP               +SP          T+Y    +++
Sbjct: 219 NPVSANRSDPVTLNVTYGPDTP--------------TISPSD--------TYYRPGANLS 256

Query: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
           ++ +  SN     S + +   Q S     +  + V   +SG+Y C A +++       + 
Sbjct: 257 LSCYAASNPPAQYSWLINGTFQQSTQELFIPNITV--NNSGSYTCHANNSVTGCNRTTVK 314

Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR 213
             +     PV  K +   +   V    +  ++T    + +    +  WF  +  L  + R
Sbjct: 315 TIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTC---STNDTGISIRWFFKNQSLPSSER 371

Query: 214 --------TFTIHAVSREHEGLYRCLVSN 234
                   T +I+ V RE  G Y C V N
Sbjct: 372 MKLSQGNTTLSINPVKREDAGTYWCEVFN 400


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score =  156 bits (395), Expect = 4e-38
 Identities = 93/278 (33%), Positives = 142/278 (51%), Gaps = 10/278 (3%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184
             V R D+ +Y+CE ++ + ++RSD + L+V YGPD P    L +   SGE        +
Sbjct: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244
           +       S+PP  Y+WF ++     +T+   I  ++  + G Y C   NS T L+    
Sbjct: 255 LNLSCHAASNPPAQYSWF-VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313

Query: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304
             + V      P +  ++ N VE+  +V LTC+   Q+    W+++ Q L  S  LQLS 
Sbjct: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373

Query: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           DNRTL +  + RND GPY C + N  S   S+P+ L +
Sbjct: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411



 Score =  154 bits (390), Expect = 1e-37
 Identities = 99/297 (33%), Positives = 141/297 (47%), Gaps = 16/297 (5%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KP I  +    +E +D V   C  +  N T  W  NN S+    R+QLS D + LT+
Sbjct: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           L V R D G Y+C  ++ L    SDP+ L+V YGPD   I       S        G ++
Sbjct: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +      S+PP  Y+W +  +I  HT   F I  ++ ++ GLY C  +NSA+  S     
Sbjct: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492

Query: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305
            + V   L  P +  ++   VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  
Sbjct: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552

Query: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL--------TINCPQSSSLSSGA 354
           NRTL +  + RND   Y C + N  S  RS+P+ L         I  P  SS  SGA
Sbjct: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGA 609



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)

Query: 2   GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48
           GP D     S+ ++  G+ LS S     +PPA     ++ N    TQ         ++  
Sbjct: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473

Query: 49  LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100
           L       +   H R        S EL KPSI+ +    +E KD V F C  +  N T  
Sbjct: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533

Query: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160
           W  N  S+    R+QLS   + LT+  V R D+  Y C  ++++ + RSDP+ LDV YGP
Sbjct: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593

Query: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220
           D       + + S      + G+++     + S+P   Y+W  ++ I    T+   I  +
Sbjct: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645

Query: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256
           +  + G Y C VSN AT  ++     + V  + T P
Sbjct: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 47/159 (29%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262
           L+ +I+ + T  +T+H +  +       LV+  AT        + RV   L  P +  ++
Sbjct: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153

Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
              VE+  +V  TC+   Q     W+++ Q L  S  LQLS  NRTL +  + RNDT  Y
Sbjct: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213

Query: 323 ACEVWNWGSRARSEPLELTI----NCPQSSSLSSGAIAG 357
            CE  N  S  RS+ + L +    + P  S L++   +G
Sbjct: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG 252



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 70/335 (20%), Positives = 128/335 (38%), Gaps = 47/335 (14%)

Query: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
           P   W   W  +LL+ASL T W+PP  A+LT+ + P +  + ++V+L V   P+   + G
Sbjct: 7   PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64

Query: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
            S            G  ++    +  Y         I          +  R  +  +  +
Sbjct: 65  YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107

Query: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181
           L   I+Q  D+G Y     +  L+++ +   F      P P        ++S     V +
Sbjct: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159

Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
             ++ F  E ++       W    S+       LS+  RT T+  V+R     Y+C   N
Sbjct: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219

Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
             +   S  ++ + VL     P + P + +   +  +++L+C    N      WF++G  
Sbjct: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275

Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                        + L I  +  N++G Y C+  N
Sbjct: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHN 303



 Score = 59.3 bits (142), Expect = 8e-09
 Identities = 81/345 (23%), Positives = 141/345 (40%), Gaps = 53/345 (15%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           N L    S+ V+L V   P  P I              SP          T+Y    +++
Sbjct: 397 NKLSVDHSDPVILNVLYGPDDPTI--------------SPS--------YTYYRPGVNLS 434

Query: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
           ++ H  SN     S +    +Q  +  + L I  +  ++SG Y C+A ++        + 
Sbjct: 435 LSCHAASNPPAQYSWLIDGNIQ--QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVK 492

Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207
                   P     +  ++S     V +  ++ F  E ++       W    S+      
Sbjct: 493 TITVSAELP-----KPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRL 547

Query: 208 -LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLV 266
            LS+  RT T+  V+R     Y C + NS +   S   + + VL     P + P   + +
Sbjct: 548 QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRS-DPVTLDVLYGPDTPIISPPDSSYL 606

Query: 267 ENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACE 325
             A +++L+C +  N S    W ++G   +P +H Q+      L I  +  N+ G YAC 
Sbjct: 607 SGA-NLNLSCHSASNPSPQYSWRING---IPQQHTQV------LFIAKITPNNNGTYACF 656

Query: 326 VWNWGS-RARSEPLELTINCPQSS-SLSSGAIAGIVIGILAVIAV 368
           V N  + R  S    +T++   +S  LS+GA  GI+IG+L  +A+
Sbjct: 657 VSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVAL 701



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 66/333 (19%), Positives = 124/333 (37%), Gaps = 56/333 (16%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A +S+ V+L V   P  P               +SP        + T Y + +++N
Sbjct: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256

Query: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153
           ++ H  SN     S   +   Q S     +  + V   +SG+Y C+A ++        + 
Sbjct: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314

Query: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207
               Y   P      +   +   VE  +  ++T   E ++     Y W++ +        
Sbjct: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368

Query: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265
             LS+  RT T+ +V+R   G Y C + N  + +     + + VL     P + P S   
Sbjct: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426

Query: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324
                ++ L+C    N      W + G          +    + L I  +   ++G Y C
Sbjct: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477

Query: 325 EVWNWG---SRARSEPLELTINCPQSSSLSSGA 354
           +  N     SR   + + ++   P+ S  S+ +
Sbjct: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNS 510


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score =  105 bits (262), Expect = 9e-23
 Identities = 60/175 (34%), Positives = 88/175 (50%), Gaps = 8/175 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           EL KPSI+ +    +E KD V F C  +  N T  W  N  S+    R+QLS     LT+
Sbjct: 143 ELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTL 202

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           L V+R D+G+Y+CE ++   + RSDP+ L+V YGPD   I       S        G ++
Sbjct: 203 LSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGPTI-------SPSKANYRPGENL 255

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLS 240
                  S+PP  Y+WF ++     +T+   I  ++  + G Y C   NSAT L+
Sbjct: 256 NLSCHAASNPPAQYSWF-INGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLN 309



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 78/367 (21%), Positives = 142/367 (38%), Gaps = 47/367 (12%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W  +LL+ASL T W+PP  A+LT+ + P +  + ++V+L     P+            + 
Sbjct: 15  WKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQN-----------RI 63

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
             +   G  ++   ++  Y         I          +  R  +  +  +L I  V +
Sbjct: 64  GYSWYKGERVDGNSLIVGY--------VIGTQQATPGPAYSGRETIYPNASLL-IQNVTQ 114

Query: 131 EDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLA 189
            D+G Y  +  +  L+++ +   F      P P        ++S     V +  ++ F  
Sbjct: 115 NDTGFYTLQVIKSDLVNEEATGQFHVYPELPKP-------SISSNNSNPVEDKDAVAFTC 167

Query: 190 ETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL 242
           E +        W    S+       LS+   T T+ +V R   G Y C + N A+   S 
Sbjct: 168 EPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRS- 226

Query: 243 GTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQ 301
             + + VL     P + PS  N      +++L+C    N      WF++G          
Sbjct: 227 DPVTLNVLYGPDGPTISPSKAN-YRPGENLNLSCHAASNPPAQYSWFING---------T 276

Query: 302 LSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAGIVIG 361
                + L I  +  N++G Y C+  N  +      + +      +  LS+ A  GI IG
Sbjct: 277 FQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIG 336

Query: 362 ILAVIAV 368
           +LA +A+
Sbjct: 337 VLARVAL 343


>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
           16 [Homo sapiens]
          Length = 484

 Score =  103 bits (258), Expect = 3e-22
 Identities = 71/293 (24%), Positives = 130/293 (44%), Gaps = 18/293 (6%)

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           LA+P++  +    +E++D +   C++      + W  N  ++    R+ LS DG++L   
Sbjct: 189 LAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARH 248

Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
            ++RE++G YQCE  + +   RS+PI L V +GP+ V I  +S   +G  ++V   +S+T
Sbjct: 249 GIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTTRTGCTIKVDFNTSLT 308

Query: 187 FLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLK 246
               ++S P   Y W      L +      I +++   EG Y C+  N+ T LS   ++ 
Sbjct: 309 LWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVV 368

Query: 247 VRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHL------ 300
           V++        +VP      E  + V LT Q   + + V  +  G    P+  L      
Sbjct: 369 VKLSAAAVATMIVPVPTKPTE-GQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427

Query: 301 -----------QLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
                      ++   N +L++  L   DTG Y  +      +  +  +EL +
Sbjct: 428 TWIAGPAHTGREVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQV 480



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 59/194 (30%), Positives = 89/194 (45%), Gaps = 27/194 (13%)

Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWF---------LLDSIL----------SHTTR-- 213
           E  +  EG ++T +    S    AY+W+         L+ S +          +HT R  
Sbjct: 86  EPAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHTGREA 145

Query: 214 -----TFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVEN 268
                +  I  +   H G Y     N     + +G   V+V E L  P V+ +S  LVE 
Sbjct: 146 VRPDGSLDIQGILPRHSGTYILQTFNRQLQ-TEVGYGHVQVHEILAQPTVLANSTALVER 204

Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
             ++ L C + + +  V+WF +G  L  +  L LS D R L  HG++R + G Y CEVWN
Sbjct: 205 RDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWN 264

Query: 329 WGSRARSEPLELTI 342
             S +RSEP+ LT+
Sbjct: 265 PVSVSRSEPINLTV 278


>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
           sapiens]
          Length = 426

 Score =  101 bits (252), Expect = 1e-21
 Identities = 81/343 (23%), Positives = 147/343 (42%), Gaps = 40/343 (11%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+PP  A++T+ A P   ++ +DV+L V   P+              
Sbjct: 15  WKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQN------------- 61

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
                PG    + +M   Y      +  I ++ +   +++   +   +       L I  
Sbjct: 62  ----LPGYFWYKGEMTDLY------HYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQN 111

Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
           V R+D+GTY        + +R D    ++++    + ++      S   +   E      
Sbjct: 112 VTRKDAGTYTLH-----IIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVR 166

Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
           L         +Y W++    L        S T RT  +  V++   G Y C + N  +  
Sbjct: 167 LICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVS-A 225

Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
           S    + + +L  L +P +  ++LN  EN   +  TC+  +++    W+L+GQ L  S  
Sbjct: 226 SRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPG 285

Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 286 VKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNV 328



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 66/213 (30%), Positives = 97/213 (45%), Gaps = 22/213 (10%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P           P I ++     E KD++ F C  K  N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLPI----------PYITINNLNPRENKDVLAFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+     ++   + +IL +  V R ++G YQCE RD     RS+P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNV 328

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD   I                G ++     T+S+PP  Y W +         + F 
Sbjct: 329 LYGPDLPRI-------YPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLF- 380

Query: 217 IHAVSREHEGLYRCLVSNSAT--HLSSLGTLKV 247
           I  ++R H GLY C V NSAT   +S   T+KV
Sbjct: 381 IPQITRNHSGLYACSVHNSATGKEISKSMTVKV 413



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 69/272 (25%), Positives = 116/272 (42%), Gaps = 27/272 (9%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KP I+ S     E  + V   C  + ++ +  W  N  S+    R+QLSK  + L +
Sbjct: 145 ETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQLSKTNRTLYL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE R+ + + RSDP+ L++     P+     + +   E  +V     +
Sbjct: 205 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPIPYITINNLNPRENKDV-----L 258

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
            F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +   
Sbjct: 259 AFTCEPKSE-NYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYG 317

Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLLP 296
            L S   + + VL    +P++ P S     +  ++DL+C T  N      W ++G     
Sbjct: 318 GLRS-NPVILNVLYGPDLPRIYP-SFTYYRSGENLDLSCFTESNPPAEYFWTING----- 370

Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
               +     + L I  + RN +G YAC V N
Sbjct: 371 ----KFQQSGQKLFIPQITRNHSGLYACSVHN 398


>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
          Length = 426

 Score =  100 bits (249), Expect = 3e-21
 Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
           W G+LL+ASL   W+ P  AQ+T+ A P   ++ +DV+L V   P+    +    G+ R+
Sbjct: 15  WKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L                  +T Y    D  I I+  +       +   + +     L I 
Sbjct: 75  LYH---------------YITSYVV--DGEIIIYGPA-------YSGRETAYSNASLLIQ 110

Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
            V RED+G+Y        +    +  + +  + L+    P P        ++S  +   E
Sbjct: 111 NVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLET---PKP-------SISSSNLNPRE 160

Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
            ME  S+T   ET   P  +Y W++    L        S T RT  +  V++   G Y C
Sbjct: 161 TMEAVSLTCDPET---PDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYEC 217

Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
            + N  +  S    + + +L  L  P +  ++LN  EN   ++ TC+  +++    W+L+
Sbjct: 218 EIRNPVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLN 276

Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS+P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328



 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 69/214 (32%), Positives = 102/214 (47%), Gaps = 22/214 (10%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P          KP I ++     E KD++ F C  K  N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVLNFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328

Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
            YGPD P      +   SGEV+ +             S+PP  Y+W + +       + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINEKFQLPGQKLF 380

Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
             H ++ +H GLY C V NSAT   S  ++ V V
Sbjct: 381 IRH-ITTKHSGLYVCSVRNSATGKESSKSMTVEV 413



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 63/273 (23%), Positives = 110/273 (40%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V+  C  +  + +  W  N  S+     ++LS+  + L +
Sbjct: 145 ETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
           L V +  +G Y+CE R+ + + RSDP+ L++         KL     +   +   E    
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
           + F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRY 316

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     +   + L+C    N      W ++ +  L
Sbjct: 317 GGIRS-DPVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQL 374

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
           P +          L I  +    +G Y C V N
Sbjct: 375 PGQ---------KLFIRHITTKHSGLYVCSVRN 398


>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
           [Homo sapiens]
          Length = 419

 Score =  100 bits (248), Expect = 4e-21
 Identities = 85/343 (24%), Positives = 148/343 (43%), Gaps = 40/343 (11%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+PP  AQ+T+ A P   ++ +DV+L V   P+    +         
Sbjct: 15  WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGY--------- 65

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
                    I  K  +T+        IT + V     +    +  R ++  +  +L I  
Sbjct: 66  ---------IWYKGQMTYLYHY----ITSYVVDGQRIIYGPAYSGRERVYSNASLL-IQN 111

Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
           V +ED+G+Y        + +R D       +    + ++      S   +   E      
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166

Query: 188 LAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
           L    + P  +Y W++    L        S T RT  I  V++   G Y C + N  +  
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225

Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEH 299
           S    + + +L  L+ P +  ++LN  EN   +  TC+  +++    W+L+GQ L  S  
Sbjct: 226 SRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPKSKNYTYIWWLNGQSLPVSPR 285

Query: 300 LQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           ++   +NR LI+  + RN+TGPY CE+ +     RS+P+ L +
Sbjct: 286 VKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 20/213 (9%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +              +L+KP I ++     E KD++TF C  K  N
Sbjct: 221 NPVSASRSDPVTLNLLP------------KLSKPYITINNLNPRENKDVLTFTCEPKSKN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD     L S   S       E   ++  AE  S+P   Y+W  ++     + +  +
Sbjct: 329 LYGPD-----LPSIYPSFTYYRSGENLYLSCFAE--SNPRAQYSW-TINGKFQLSGQKLS 380

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
           I  ++ +H GLY C V NSAT   S  ++ V+V
Sbjct: 381 IPQITTKHSGLYACSVRNSATGKESSKSITVKV 413


>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
           [Homo sapiens]
          Length = 419

 Score =  100 bits (248), Expect = 4e-21
 Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
           W G+LL+ASL   W+PP  AQ+T+ A P   ++ +DV+L V   P+    +    G+ R+
Sbjct: 15  WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L                  +T Y    D  I I+         +  R  +  +  +L I 
Sbjct: 75  LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110

Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
            V +ED+G+Y        +    +    +  ++L+    P P        ++S ++   E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160

Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
            ME  S+T   ET   P  +Y W++    L        S T RT  +  V++   G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217

Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
            + N  +  S      + +L  L  P +  ++L   EN   ++ TC+  +++    W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276

Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+   L +   P+ P          KP I ++     E KD++ F C  K  N
Sbjct: 221 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328

Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
            YGPD P      +   SGEV+ +             S+PP  Y+W +         + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 380

Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
            I  ++ +H GLY C V NSAT   S  ++ V+V
Sbjct: 381 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V+  C  +  + +  W  N  S+    R+QLS+  + L +
Sbjct: 145 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
           L V +  +G Y+CE R+ + + RSDP  L++         KL     +   ++  E    
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 257

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
           + F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 316

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     +   + L+C    N      W ++G+   
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 371

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                QLS   + L I  +    +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398


>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
           [Homo sapiens]
          Length = 426

 Score =  100 bits (248), Expect = 4e-21
 Identities = 91/352 (25%), Positives = 155/352 (44%), Gaps = 58/352 (16%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
           W G+LL+ASL   W+PP  AQ+T+ A P   ++ +DV+L V   P+    +    G+ R+
Sbjct: 15  WKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L                  +T Y    D  I I+         +  R  +  +  +L I 
Sbjct: 75  LYH---------------YITSYVV--DGQIIIY------GPAYSGRETIYSNASLL-IQ 110

Query: 127 IVQREDSGTYQC------EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--E 178
            V +ED+G+Y        +    +    +  ++L+    P P        ++S ++   E
Sbjct: 111 NVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLET---PKP-------SISSSKLNPRE 160

Query: 179 VMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRC 230
            ME  S+T   ET   P  +Y W++    L        S T RT  +  V++   G Y C
Sbjct: 161 AMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYEC 217

Query: 231 LVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLS 290
            + N  +  S      + +L  L  P +  ++L   EN   ++ TC+  +++    W+L+
Sbjct: 218 EIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLN 276

Query: 291 GQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 277 GQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+   L +   P+ P          KP I ++     E KD++ F C  K  N
Sbjct: 221 NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 328

Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
            YGPD P      +   SGEV+ +             S+PP  Y+W +         + F
Sbjct: 329 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 380

Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
            I  ++ +H GLY C V NSAT   S  ++ V+V
Sbjct: 381 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V+  C  +  + +  W  N  S+    R+QLS+  + L +
Sbjct: 145 ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
           L V +  +G Y+CE R+ + + RSDP  L++         KL     +   ++  E    
Sbjct: 205 LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 257

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
           + F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 258 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 316

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     +   + L+C    N      W ++G+   
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 371

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                QLS   + L I  +    +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398


>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
           [Homo sapiens]
          Length = 419

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 67/213 (31%), Positives = 100/213 (46%), Gaps = 20/213 (9%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P          KP I ++     E KD+ TF C  K  N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVSTFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RSDP+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD   I                G ++       S+PP  Y+W  ++     + +  +
Sbjct: 329 LYGPDLPRI-------YPSFTYYHSGQNLYLSCFADSNPPAQYSW-TINGKFQLSGQKLS 380

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
           I  ++ +H GLY C V NSAT   S  ++ VRV
Sbjct: 381 IPQITTKHSGLYACSVRNSATGKESSKSVTVRV 413



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 88/345 (25%), Positives = 146/345 (42%), Gaps = 44/345 (12%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIH----GRSRE 66
           W G+LL+ASL   W+PP  AQ+T+ A P   ++ +DV+L V   P+    +    G+ R+
Sbjct: 15  WKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L          T+      +  Y        T++   +N S++     Q  +D    T+ 
Sbjct: 75  LYHYV------TSYIVDGQIIKYGPAYSGRETVY---SNASLLIQNVTQ--EDTGSYTLH 123

Query: 127 IVQRED-SGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           I++R D +G         L  +   P      + P                 E  E   +
Sbjct: 124 IIKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPR----------------EATEAVIL 167

Query: 186 TFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
           T   ET   P  +Y W++    L        S T RT  +  V+    G Y C + N  +
Sbjct: 168 TCDPET---PDASYLWWMNGQSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVS 224

Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPS 297
             S    + + +L  L  P +  ++LN  EN      TC+  +++    W+L+GQ L  S
Sbjct: 225 -ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVS 283

Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
             ++   +NR LI+  + RN+TGPY CE+ +     RS+P+ L +
Sbjct: 284 PRVKRRIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNV 328



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 67/273 (24%), Positives = 113/273 (41%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W  N  S+     +QLS+  + L +
Sbjct: 145 ETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSETNRTLYL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V    +G Y+CE R+ + + RSDP+ L++         KL     +   +   E   +
Sbjct: 205 FGVTNYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257

Query: 186 -TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
            TF  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 258 STFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRY 316

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     + +++ L+C    N      W ++G+   
Sbjct: 317 GGIRS-DPVTLNVLYGPDLPRIYP-SFTYYHSGQNLYLSCFADSNPPAQYSWTINGK--- 371

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                QLS   + L I  +    +G YAC V N
Sbjct: 372 ----FQLS--GQKLSIPQITTKHSGLYACSVRN 398


>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
           8 [Homo sapiens]
          Length = 349

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 57/172 (33%), Positives = 84/172 (48%), Gaps = 8/172 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ +    +E KD V F C  +  N T  W  N  S+    R+QLS   + LT+
Sbjct: 143 ETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL 202

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
           L V R D G Y+CE ++   +  SDP+ L+V YGPD   I       S        G ++
Sbjct: 203 LSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTI-------SPSDTYYHAGVNL 255

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSAT 237
                  S+PP  Y+W +  +   +T + F I  ++ ++ G Y C  +NSAT
Sbjct: 256 NLSCHAASNPPSQYSWSVNGTFQQYTQKLF-IPNITTKNSGSYACHTTNSAT 306



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 90/380 (23%), Positives = 158/380 (41%), Gaps = 52/380 (13%)

Query: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62
           P+  W   W G+LL+ASL T W+PP  AQLT+ A P +A + ++V+L V   P+ P+ + 
Sbjct: 7   PSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRGYN 66

Query: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122
             +           G  ++    +  Y  +    IT     +N   ++     L ++   
Sbjct: 67  WYK-----------GETVDANRRIIGYVISNQ-QITPGPAYSNRETIYPNASLLMRN--- 111

Query: 123 LTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEG 182
                V R D+G+Y  +     L+  S+ +       P+  +  + S   +   VE  + 
Sbjct: 112 -----VTRNDTGSYTLQV--IKLNLMSEEVTGQFSVHPETPKPSISSN--NSNPVEDKDA 162

Query: 183 SSMTFLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSN 234
            + T   ET++     Y W++            LS+  RT T+ +V+R   G Y C + N
Sbjct: 163 VAFTCEPETQN---TTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQN 219

Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293
            A+   S   + + VL     P + PS         +++L+C    N      W ++G  
Sbjct: 220 PASANFS-DPVTLNVLYGPDAPTISPSD-TYYHAGVNLNLSCHAASNPPSQYSWSVNG-- 275

Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP----QSS 348
                        + L I  +   ++G YAC   N  + R R+    +T++       S 
Sbjct: 276 -------TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSP 328

Query: 349 SLSSGAIAGIVIGILAVIAV 368
            LS+ A   I+IG+LA +A+
Sbjct: 329 GLSARATVSIMIGVLARVAL 348


>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
           sapiens]
          Length = 428

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 89/348 (25%), Positives = 150/348 (43%), Gaps = 50/348 (14%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+A L   W+ P  AQ+T+ A P   ++ +DV+L V   P+              
Sbjct: 15  WKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQ-------------- 60

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSV---VFHERMQLSKDGKILTILI 127
           ++A       + KD+  +        IT + V   + +    +  R  +  +  +L I  
Sbjct: 61  NLAGYIWYKGQMKDLYHY--------ITSYVVDGQIIIYGPAYSGRETVYSNASLL-IQN 111

Query: 128 VQREDSGTYQC---EARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVV--EVMEG 182
           V RED+G+Y     +  D    +     F      P P        ++S  +   E ME 
Sbjct: 112 VTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKP-------SISSSNLYPREDMEA 164

Query: 183 SSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVSN 234
            S+T   ET   P  +Y W++    L        S   RT  +  V++   G Y C + N
Sbjct: 165 VSLTCDPET---PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRN 221

Query: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPL 294
             +  S    + + +L  L  P +  ++LN  EN   +  TC+  +++    W+L+GQ L
Sbjct: 222 PVS-ASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSL 280

Query: 295 LPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
             S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 281 PVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNV 328



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 64/213 (30%), Positives = 98/213 (46%), Gaps = 20/213 (9%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P          KP I ++     E KD++ F C  K  N
Sbjct: 221 NPVSASRSDPVTLNLL--PKLP----------KPYITINNLNPRENKDVLAFTCEPKSEN 268

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE +D     RS P+ L+V
Sbjct: 269 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNV 328

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD   I                G ++       S+PP  Y+W +         + F 
Sbjct: 329 LYGPDLPRI-------YPSFTYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLF- 380

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
           I  ++ +H GLY C V NSAT + S  ++ V+V
Sbjct: 381 IPQITTKHSGLYACSVRNSATGMESSKSMTVKV 413



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 67/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V+  C  +  + +  W  N  S+     +QLSK+ + L +
Sbjct: 145 ETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLQLSKNKRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
             V +  +G Y+CE R+ + + RSDP+ L++         KL     +   +   E    
Sbjct: 205 FGVTKYTAGPYECEIRNPVSASRSDPVTLNLL-------PKLPKPYITINNLNPRENKDV 257

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
           + F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 258 LAFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIQDRY 316

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     +  ++ L+C    N      W ++G+   
Sbjct: 317 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYHSGENLYLSCFADSNPPAEYSWTINGK--- 371

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                QLS   + L I  +    +G YAC V N
Sbjct: 372 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 398


>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
           sapiens]
          Length = 435

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 69/228 (30%), Positives = 104/228 (45%), Gaps = 21/228 (9%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P           P I ++     E+KD++ F C  K  N
Sbjct: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS+P+ L+V
Sbjct: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD   I                G ++       S+PP  Y+W +         + F 
Sbjct: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379

Query: 217 IHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLN 264
           I  ++  H GLY C V NSAT      ++ V+V ET + PQV  +  N
Sbjct: 380 IPQITTNHSGLYACSVRNSATGKEISKSMIVKVSETAS-PQVTYAGPN 426



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 89/349 (25%), Positives = 145/349 (41%), Gaps = 53/349 (15%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+ P  AQ+ + A P   ++ +DV+L V   P+    +         
Sbjct: 15  WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65

Query: 71  SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
                    I  K  +T    Y T+  V+  I +        +  R  +  +  +L I  
Sbjct: 66  ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110

Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
           V +ED+G+Y        + +R D        F    Y   P      S +   EV+E + 
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165

Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
                 L      P  +Y W L    L        S T RT  +  V++   G Y C + 
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219

Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
           N  +  S    + + +L  L MP +  ++LN  E    +  TC+  +++    W+L+GQ 
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278

Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 27/272 (9%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W+ N  ++    R+QLSK  + L +
Sbjct: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE R+ + + RSDP+ L++     P+     + +   E  +V     +
Sbjct: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPMPYITINNLNPREKKDV-----L 257

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
            F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +   
Sbjct: 258 AFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYG 316

Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLP 296
            + S   + + VL    +P++ P S     +  ++DL+C    N      W ++G+    
Sbjct: 317 GIRS-NPVTLNVLYGPDLPRIYP-SFTYYRSGENLDLSCFADSNPPAEYSWTINGK---- 370

Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
               QLS   + L I  +  N +G YAC V N
Sbjct: 371 ---FQLS--GQKLFIPQITTNHSGLYACSVRN 397


>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           +L KP I ++     E KD++ F C  K  N T  W  N  S+    R++   + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V R ++G Y+CE RD     RSDP+ L+V YGPD     L S   S       E   +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +  AE  S+PP  Y W  ++     + +  +I  ++ +H GLY C V NSAT   S  ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316

Query: 246 KVRV 249
            V V
Sbjct: 317 TVEV 320



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 1/134 (0%)

Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
           ++  +  I  V+RE  G Y   +         + G     +   L  P +  ++    EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161

Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
              +  TC+  +++    W+L+GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221

Query: 329 WGSRARSEPLELTI 342
                RS+P+ L +
Sbjct: 222 RDGGMRSDPVTLNV 235



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 73/346 (21%), Positives = 128/346 (36%), Gaps = 48/346 (13%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+ P  AQ+T+ A P   ++ +DV+L V   P+              
Sbjct: 15  WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
                 G  ++    +T Y     +NI            +  R  +  +  +L I  V R
Sbjct: 64  GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114

Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
           ED+G+Y        + +R D       Y    + +KL     +    +  E    + F  
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169

Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
           E KS     Y W+L    L  +         R   + +V+R   G Y C + +    + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228

Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
              + + VL    +P + P S     +  ++ L+C    N      W ++G         
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP 345
           +     + L I  +     G Y C V N  + +  S+ + + ++ P
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323


>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 8/184 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           +L KP I ++     E KD++ F C  K  N T  W  N  S+    R++   + +IL +
Sbjct: 145 KLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILIL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V R ++G Y+CE RD     RSDP+ L+V YGPD     L S   S       E   +
Sbjct: 205 PSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPD-----LPSIYPSFTYYRSGENLYL 259

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +  AE  S+PP  Y W  ++     + +  +I  ++ +H GLY C V NSAT   S  ++
Sbjct: 260 SCFAE--SNPPAEYFW-TINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSM 316

Query: 246 KVRV 249
            V V
Sbjct: 317 TVEV 320



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 1/134 (0%)

Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSL-GTLKVRVLETLTMPQVVPSSLNLVEN 268
           ++  +  I  V+RE  G Y   +         + G     +   L  P +  ++    EN
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPREN 161

Query: 269 ARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
              +  TC+  +++    W+L+GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +
Sbjct: 162 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRD 221

Query: 329 WGSRARSEPLELTI 342
                RS+P+ L +
Sbjct: 222 RDGGMRSDPVTLNV 235



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 73/346 (21%), Positives = 128/346 (36%), Gaps = 48/346 (13%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+ P  AQ+T+ A P   ++ +DV+L V   P+              
Sbjct: 15  WKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQN-----------LA 63

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILIVQR 130
                 G  ++    +T Y     +NI            +  R  +  +  +L I  V R
Sbjct: 64  GYIWYKGQLMDLYHYITSYVVDGQINI--------YGPAYTGRETVYSNASLL-IQNVTR 114

Query: 131 EDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS-MTFLA 189
           ED+G+Y        + +R D       Y    + +KL     +    +  E    + F  
Sbjct: 115 EDAGSYTLH-----IIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTC 169

Query: 190 ETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSATHLSS 241
           E KS     Y W+L    L  +         R   + +V+R   G Y C + +    + S
Sbjct: 170 EPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRS 228

Query: 242 LGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSEHL 300
              + + VL    +P + P S     +  ++ L+C    N      W ++G         
Sbjct: 229 -DPVTLNVLYGPDLPSIYP-SFTYYRSGENLYLSCFAESNPPAEYFWTING--------- 277

Query: 301 QLSADNRTLIIHGLQRNDTGPYACEVWNWGS-RARSEPLELTINCP 345
           +     + L I  +     G Y C V N  + +  S+ + + ++ P
Sbjct: 278 KFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAP 323


>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
           [Homo sapiens]
          Length = 424

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 89/349 (25%), Positives = 145/349 (41%), Gaps = 53/349 (15%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+ P  AQ+ + A P   ++ +DV+L V   P+    +         
Sbjct: 15  WKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTGY--------- 65

Query: 71  SIAVSPGTAIEQKDMVT---FYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTILI 127
                    I  K  +T    Y T+  V+  I +        +  R  +  +  +L I  
Sbjct: 66  ---------IWYKGQMTDLYHYITSYVVHGQIIY-----GPAYSGRETVYSNASLL-IQN 110

Query: 128 VQREDSGTYQCEARDALLSQRSDPI------FLDVKYGPDPVEIKLESGVASGEVVEVME 181
           V +ED+G+Y        + +R D        F    Y   P      S +   EV+E + 
Sbjct: 111 VTQEDAGSYTLH-----IIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVR 165

Query: 182 GSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYRCLVS 233
                 L      P  +Y W L    L        S T RT  +  V++   G Y C + 
Sbjct: 166 ------LICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIR 219

Query: 234 NSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQP 293
           N  +  S    + + +L  L MP +  ++LN  E    +  TC+  +++    W+L+GQ 
Sbjct: 220 NPVS-ASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQS 278

Query: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 279 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327



 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 61/201 (30%), Positives = 91/201 (45%), Gaps = 20/201 (9%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+ V L +   P+ P           P I ++     E+KD++ F C  K  N
Sbjct: 220 NPVSASRSDPVTLNLL--PKLPM----------PYITINNLNPREKKDVLAFTCEPKSRN 267

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS+P+ L+V
Sbjct: 268 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNV 327

Query: 157 KYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFT 216
            YGPD   I                G ++       S+PP  Y+W +         + F 
Sbjct: 328 LYGPDLPRI-------YPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLF- 379

Query: 217 IHAVSREHEGLYRCLVSNSAT 237
           I  ++  H GLY C V NSAT
Sbjct: 380 IPQITTNHSGLYACSVRNSAT 400



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 69/272 (25%), Positives = 118/272 (43%), Gaps = 27/272 (9%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W+ N  ++    R+QLSK  + L +
Sbjct: 144 ETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNGQNLPMTHRLQLSKTNRTLYL 203

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE R+ + + RSDP+ L++     P+     + +   E  +V     +
Sbjct: 204 FGVTKYIAGPYECEIRNPVSASRSDPVTLNL-LPKLPMPYITINNLNPREKKDV-----L 257

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSAT 237
            F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +   
Sbjct: 258 AFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYG 316

Query: 238 HLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLP 296
            + S   + + VL    +P++ P S     +  ++DL+C    N      W ++G+    
Sbjct: 317 GIRS-NPVTLNVLYGPDLPRIYP-SFTYYRSGENLDLSCFADSNPPAEYSWTINGK---- 370

Query: 297 SEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
               QLS   + L I  +  N +G YAC V N
Sbjct: 371 ---FQLS--GQKLFIPQITTNHSGLYACSVRN 397


>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
           [Homo sapiens]
          Length = 297

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 67/214 (31%), Positives = 100/214 (46%), Gaps = 22/214 (10%)

Query: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96
           NP+ A++S+   L +   P+ P          KP I ++     E KD++ F C  K  N
Sbjct: 99  NPVSASRSDPFTLNLL--PKLP----------KPYITINNLKPRENKDVLNFTCEPKSEN 146

Query: 97  ITIHWVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDV 156
            T  W  N  S+    R++   + +IL +  V R ++G YQCE RD     RS P+ L+V
Sbjct: 147 YTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 206

Query: 157 KYGPD-PVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTF 215
            YGPD P      +   SGEV+ +             S+PP  Y+W +         + F
Sbjct: 207 LYGPDLPRIYPSFTYYRSGEVLYLS--------CSADSNPPAQYSWTINGKFQLSGQKLF 258

Query: 216 TIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRV 249
            I  ++ +H GLY C V NSAT   S  ++ V+V
Sbjct: 259 -IPQITTKHSGLYACSVRNSATGKESSKSMTVKV 291



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 12/173 (6%)

Query: 178 EVMEGSSMTFLAETKSHPPCAYTWFLLDSIL--------SHTTRTFTIHAVSREHEGLYR 229
           E ME  S+T   ET   P  +Y W++    L        S T RT  +  V++   G Y 
Sbjct: 38  EAMEAVSLTCDPET---PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYE 94

Query: 230 CLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFL 289
           C + N  +  S      + +L  L  P +  ++L   EN   ++ TC+  +++    W+L
Sbjct: 95  CEIRNPVS-ASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWL 153

Query: 290 SGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342
           +GQ L  S  ++   +NR LI+  + RN+TGPY CE+ +     RS P+ L +
Sbjct: 154 NGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNV 206



 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 34/87 (39%), Positives = 47/87 (54%)

Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
           P +  S LN  E   +V LTC       +  W+++GQ L  S  LQLS  NRTL + G+ 
Sbjct: 27  PSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVT 86

Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
           +   GPY CE+ N  S +RS+P  L +
Sbjct: 87  KYTAGPYECEIRNPVSASRSDPFTLNL 113



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 29/273 (10%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V+  C  +  + +  W  N  S+    R+QLS+  + L +
Sbjct: 23  ETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRLQLSETNRTLFL 82

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSS- 184
           L V +  +G Y+CE R+ + + RSDP  L++         KL     +   ++  E    
Sbjct: 83  LGVTKYTAGPYECEIRNPVSASRSDPFTLNLL-------PKLPKPYITINNLKPRENKDV 135

Query: 185 MTFLAETKSHPPCAYTWFLLDSILSHT--------TRTFTIHAVSREHEGLYRCLVSNSA 236
           + F  E KS     Y W+L    L  +         R   + +V+R   G Y+C + +  
Sbjct: 136 LNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQY 194

Query: 237 THLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQT-VNQSVNVQWFLSGQPLL 295
             + S   + + VL    +P++ P S     +   + L+C    N      W ++G+   
Sbjct: 195 GGIRSY-PVTLNVLYGPDLPRIYP-SFTYYRSGEVLYLSCSADSNPPAQYSWTINGK--- 249

Query: 296 PSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
                QLS   + L I  +    +G YAC V N
Sbjct: 250 ----FQLS--GQKLFIPQITTKHSGLYACSVRN 276


>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
           7 [Homo sapiens]
          Length = 265

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 4/117 (3%)

Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
           P +  ++ N VEN   V LTCQ   Q+    W+++ Q LL S  L LS DNRTL++    
Sbjct: 148 PSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSAT 207

Query: 316 RNDTGPYACEVWNWGSRARSEPLELTINC----PQSSSLSSGAIAGIVIGILAVIAV 368
           +ND GPY CE+ N    +RS+P+ L +        S  LS+G    I+IG+LA +A+
Sbjct: 208 KNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMAL 264



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 11/126 (8%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI  +    +E KD+V   C  +  N T  W  NN S++   R+ LS D + L +
Sbjct: 144 EPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVL 203

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKY------GPDPVEIKLESGVASGEVVEV 179
           L   + D G Y+CE ++ + + RSDP+ L+V+Y       PD     L +G A   ++ V
Sbjct: 204 LSATKNDIGPYECEIQNPVGASRSDPVTLNVRYESVQASSPD-----LSAGTAVSIMIGV 258

Query: 180 MEGSSM 185
           + G ++
Sbjct: 259 LAGMAL 264



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 16/41 (39%), Positives = 27/41 (65%)

Query: 11 WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPV 51
          W G+LL+ASL T W+ P +AQ  ++  P +  + ++V+L V
Sbjct: 15 WQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVV 55


>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
           sapiens]
          Length = 335

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/184 (28%), Positives = 85/184 (46%), Gaps = 8/184 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W  N  S+    R QLS+  + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE R++  + RSDP+ L++ +GPD   I                G ++
Sbjct: 205 FGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRI-------HPSYTNYRSGDNL 257

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
                  S+PP  Y+W  ++     + +   I  ++ +H GLY C V NSAT   S  +L
Sbjct: 258 YLSCFANSNPPAQYSW-TINGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSL 316

Query: 246 KVRV 249
            V+V
Sbjct: 317 TVKV 320



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 45/140 (32%), Positives = 68/140 (48%), Gaps = 11/140 (7%)

Query: 209 SHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSS 262
           +++  +  I  V+RE  G Y   +          GT  V    T T+      P +  S+
Sbjct: 101 AYSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSN 155

Query: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322
           LN  E   +V LTC       + QW+++GQ L  +   QLS  NRTL + G+ +   GPY
Sbjct: 156 LNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPY 215

Query: 323 ACEVWNWGSRARSEPLELTI 342
            CE+ N GS +RS+P+ L +
Sbjct: 216 ECEIRNSGSASRSDPVTLNL 235



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 83/369 (22%), Positives = 139/369 (37%), Gaps = 64/369 (17%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
           W G+L++ASL   W+ P  AQ+T+ A P   ++ +DV+L V   P+         G+ R+
Sbjct: 15  WKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L                  +T Y    D  I I+  +       +   + +     L I 
Sbjct: 75  L---------------YHYITSYVV--DGQIIIYGPA-------YSGRETAYSNASLLIQ 110

Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
            V RED+G+Y        + +R D       Y    + ++      S   +   E     
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165

Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
            L      P  +Y W++            LS T RT  +  V++   G Y C + NS + 
Sbjct: 166 ILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGS- 224

Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
            S    + + +L    +P++ PS  N   +  ++ L+C    N      W ++G+     
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIHPSYTN-YRSGDNLYLSCFANSNPPAQYSWTINGK----- 278

Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINCPQSSSLSSGAIAG 357
              Q S  N  L I  +    +G Y C V N  +   S           S+SL+    A 
Sbjct: 279 --FQQSGQN--LFIPQITTKHSGLYVCSVRNSATGEES-----------STSLTVKVSAS 323

Query: 358 IVIGILAVI 366
             IG+L ++
Sbjct: 324 TRIGLLPLL 332


>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W  N  S+    RMQLS+  + L +
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE  ++  + RSDP+ L++ +GPD   I          V     G ++
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
                  S+PP  Y+W +         + F I  ++ +H GLY C   NSAT   S  +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194

Query: 246 KVRVL 250
            +RV+
Sbjct: 195 TIRVI 199



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 34/87 (39%), Positives = 51/87 (58%)

Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
           P +  S+LN  E   +V LTC       +  W+++GQ L  +  +QLS  NRTL + G+ 
Sbjct: 27  PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86

Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
           +   GPY CE+WN GS +RS+P+ L +
Sbjct: 87  KYTAGPYECEIWNSGSASRSDPVTLNL 113


>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W  N  S+    RMQLS+  + L +
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE  ++  + RSDP+ L++ +GPD   I          V     G ++
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 135

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
                  S+PP  Y+W +         + F I  ++ +H GLY C   NSAT   S  +L
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 194

Query: 246 KVRVL 250
            +RV+
Sbjct: 195 TIRVI 199



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 34/87 (39%), Positives = 51/87 (58%)

Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
           P +  S+LN  E   +V LTC       +  W+++GQ L  +  +QLS  NRTL + G+ 
Sbjct: 27  PSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVT 86

Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
           +   GPY CE+WN GS +RS+P+ L +
Sbjct: 87  KYTAGPYECEIWNSGSASRSDPVTLNL 113


>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
           [Homo sapiens]
          Length = 335

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 54/185 (29%), Positives = 85/185 (45%), Gaps = 8/185 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C  +  + +  W  N  S+    RMQLS+  + L +
Sbjct: 145 ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE  ++  + RSDP+ L++ +GPD   I          V     G ++
Sbjct: 205 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI-------FPSVTSYYSGENL 257

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
                  S+PP  Y+W +         + F I  ++ +H GLY C   NSAT   S  +L
Sbjct: 258 DLSCFANSNPPAQYSWTINGKFQLSGQKLF-IPQITPKHNGLYACSARNSATGEESSTSL 316

Query: 246 KVRVL 250
            +RV+
Sbjct: 317 TIRVI 321



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 11/139 (7%)

Query: 210 HTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTM------PQVVPSSL 263
           ++  +  I  V+RE  G Y   +          GT  V    T T+      P +  S+L
Sbjct: 102 YSNASLLIQNVTREDAGSYTLHIIKRGD-----GTRGVTGYFTFTLYLETPKPSISSSNL 156

Query: 264 NLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYA 323
           N  E   +V LTC       +  W+++GQ L  +  +QLS  NRTL + G+ +   GPY 
Sbjct: 157 NPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYE 216

Query: 324 CEVWNWGSRARSEPLELTI 342
           CE+WN GS +RS+P+ L +
Sbjct: 217 CEIWNSGSASRSDPVTLNL 235



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 75/331 (22%), Positives = 125/331 (37%), Gaps = 53/331 (16%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQ----IHGRSRE 66
           W G+LL+A L   W+ P  AQ+ + A P   ++ +DV+L V   P+         G+ R+
Sbjct: 15  WKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRD 74

Query: 67  LAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTIL 126
           L                  +T Y    D  I I+         +  R  +  +  +L I 
Sbjct: 75  L---------------YHYITSYVV--DGQIIIY------GPAYSGRETVYSNASLL-IQ 110

Query: 127 IVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMT 186
            V RED+G+Y        + +R D       Y    + ++      S   +   E     
Sbjct: 111 NVTREDAGSYTLH-----IIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETV 165

Query: 187 FLAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATH 238
            L      P  +Y W++            LS T RT  +  V++   G Y C + NS + 
Sbjct: 166 ILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGS- 224

Query: 239 LSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPS 297
            S    + + +L    +P++ P S+    +  ++DL+C    N      W ++G+     
Sbjct: 225 ASRSDPVTLNLLHGPDLPRIFP-SVTSYYSGENLDLSCFANSNPPAQYSWTINGK----- 278

Query: 298 EHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
              QLS   + L I  +     G YAC   N
Sbjct: 279 --FQLS--GQKLFIPQITPKHNGLYACSARN 305


>gi|148612793 carcinoembryonic antigen-related cell adhesion
           molecule isoform 1 [Homo sapiens]
          Length = 293

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 62/196 (31%), Positives = 93/196 (47%), Gaps = 14/196 (7%)

Query: 220 VSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV 279
           V+ E  G Y   V+   + +    +  +RV E++  P +  SS  + E   SV LTC T 
Sbjct: 112 VTLEDTGYYNLQVTYRNSQIEQ-ASHHLRVYESVAQPSIQASSTTVTEKG-SVVLTCHTN 169

Query: 280 NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
           N   + QW  + Q L  ++ ++LS  N  L I  +++ D G Y CEV N  S  RS+PL+
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229

Query: 340 LTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 399
           LT+   +S   + G + G+++G L V A+      FL +R   R S     D S    Q 
Sbjct: 230 LTV---KSDDNTLGILIGVLVGSLLVAALVC----FLLLRKTGRAS-----DQSDFREQQ 277

Query: 400 IPKEEHPTEPSSESLS 415
            P       PS  S+S
Sbjct: 278 PPASTPGHGPSDSSIS 293



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 9/130 (6%)

Query: 54  TPRTPQIHGRSREL------AKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLS 107
           T R  QI   S  L      A+PSI  S  T + +K  V   C T +   +  W+ NN  
Sbjct: 125 TYRNSQIEQASHHLRVYESVAQPSIQAS-STTVTEKGSVVLTCHTNNTGTSFQWIFNNQR 183

Query: 108 VVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKL 167
           +   +RM+LS    +LTI  +++ED+G YQCE  + + S RSDP+ L VK   + + I +
Sbjct: 184 LQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKSDDNTLGILI 243

Query: 168 ESGVASGEVV 177
             GV  G ++
Sbjct: 244 --GVLVGSLL 251



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 57/248 (22%), Positives = 90/248 (36%), Gaps = 44/248 (17%)

Query: 1   MGPADSWGHH----WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPR 56
           MGP  +  H     W G+LL+ASL T W+ P  A L + + P +  + E+V L V   P 
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 57  TPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQL 116
               +G  +           G  +E   ++  Y     V              +  R  +
Sbjct: 61  NLYSYGWYK-----------GKTVEPNQLIAAYVIDTHVRTP--------GPAYSGRETI 101

Query: 117 SKDGKILTILIVQREDSGTY--QCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
           S  G  L    V  ED+G Y  Q   R++ + Q S  + +        ++    +    G
Sbjct: 102 SPSGD-LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKG 160

Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR--------TFTIHAVSREHEG 226
            VV          L    ++   ++ W   +  L  T R          TI  + +E  G
Sbjct: 161 SVV----------LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAG 210

Query: 227 LYRCLVSN 234
            Y+C VSN
Sbjct: 211 EYQCEVSN 218


>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
           [Homo sapiens]
          Length = 326

 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 57/184 (30%), Positives = 88/184 (47%), Gaps = 8/184 (4%)

Query: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125
           E  KPSI+ S     E  + V   C       +  W  N  S+    R+QLSK  + L I
Sbjct: 145 ETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFI 204

Query: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185
             V +  +G Y+CE R+ + + RSDP+ L++ +GPD     L S   S       E   +
Sbjct: 205 FGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPD-----LPSIYPSFTYYRSGENLYL 259

Query: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245
           +  AE  S+P   Y+W  ++     + +  +I  ++ +H GLY C V NSAT   S  ++
Sbjct: 260 SCFAE--SNPRAQYSW-TINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSI 316

Query: 246 KVRV 249
            V+V
Sbjct: 317 TVKV 320



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 35/87 (40%), Positives = 51/87 (58%)

Query: 256 PQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQ 315
           P +  S+LN  E   +V LTC     + + QW+++GQ L  +  LQLS  NRTL I G+ 
Sbjct: 149 PSISSSNLNPREAMEAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVT 208

Query: 316 RNDTGPYACEVWNWGSRARSEPLELTI 342
           +   GPY CE+ N  S +RS+P+ L +
Sbjct: 209 KYIAGPYECEIRNPVSASRSDPVTLNL 235



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 71/330 (21%), Positives = 125/330 (37%), Gaps = 51/330 (15%)

Query: 11  WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKP 70
           W G+LL+ASL   W+PP  AQ+T+ A P   ++ +DV+L V   P+              
Sbjct: 15  WKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ-------------- 60

Query: 71  SIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVF---HERMQLSKDGKILTILI 127
               +    I  K  +T+       +    +V +   +++   +   +       L I  
Sbjct: 61  ----NLAGYIWYKGQMTYL-----YHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQN 111

Query: 128 VQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTF 187
           V +ED+G+Y        + +R D       +    + ++      S   +   E      
Sbjct: 112 VTQEDAGSYTLH-----IIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166

Query: 188 LAETKSHPPCAYTWFLLDSI--------LSHTTRTFTIHAVSREHEGLYRCLVSNSATHL 239
           L    + P  +Y W++            LS T RT  I  V++   G Y C + N  +  
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVS-A 225

Query: 240 SSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTC-QTVNQSVNVQWFLSGQPLLPSE 298
           S    + + +L    +P + P S     +  ++ L+C    N      W ++G+      
Sbjct: 226 SRSDPVTLNLLHGPDLPSIYP-SFTYYRSGENLYLSCFAESNPRAQYSWTINGK------ 278

Query: 299 HLQLSADNRTLIIHGLQRNDTGPYACEVWN 328
             QLS   + L I  +    +G YAC V N
Sbjct: 279 -FQLS--GQKLSIPQITTKHSGLYACSVRN 305


>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
           isoform 2 [Homo sapiens]
          Length = 292

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 61/196 (31%), Positives = 90/196 (45%), Gaps = 15/196 (7%)

Query: 220 VSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV 279
           V+ E  G Y   V+   + +    +  +RV E++  P +  SS  + E   SV LTC T 
Sbjct: 112 VTLEDTGYYNLQVTYRNSQIEQ-ASHHLRVYESVAQPSIQASSTTVTEKG-SVVLTCHTN 169

Query: 280 NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLE 339
           N   + QW  + Q L  ++ ++LS  N  L I  +++ D G Y CEV N  S  RS+PL+
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229

Query: 340 LTINCPQSSSLSSGAIAGIVIGILAVIAVASELGYFLYIRNARRPSRKTTEDPSHETSQP 399
           LT+    +         GI+IG+L    + + L  FL +R   R S     D S    Q 
Sbjct: 230 LTVKYDNT--------LGILIGVLVGSLLVAALVCFLLLRKTGRAS-----DQSDFREQQ 276

Query: 400 IPKEEHPTEPSSESLS 415
            P       PS  S+S
Sbjct: 277 PPASTPGHGPSDSSIS 292



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 42/111 (37%), Positives = 59/111 (53%), Gaps = 7/111 (6%)

Query: 54  TPRTPQIHGRSREL------AKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLS 107
           T R  QI   S  L      A+PSI  S  T + +K  V   C T +   +  W+ NN  
Sbjct: 125 TYRNSQIEQASHHLRVYESVAQPSIQAS-STTVTEKGSVVLTCHTNNTGTSFQWIFNNQR 183

Query: 108 VVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKY 158
           +   +RM+LS    +LTI  +++ED+G YQCE  + + S RSDP+ L VKY
Sbjct: 184 LQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 57/248 (22%), Positives = 90/248 (36%), Gaps = 44/248 (17%)

Query: 1   MGPADSWGHH----WMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPR 56
           MGP  +  H     W G+LL+ASL T W+ P  A L + + P +  + E+V L V   P 
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 57  TPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQL 116
               +G  +           G  +E   ++  Y     V              +  R  +
Sbjct: 61  NLYSYGWYK-----------GKTVEPNQLIAAYVIDTHVRTP--------GPAYSGRETI 101

Query: 117 SKDGKILTILIVQREDSGTY--QCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASG 174
           S  G  L    V  ED+G Y  Q   R++ + Q S  + +        ++    +    G
Sbjct: 102 SPSGD-LHFQNVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKG 160

Query: 175 EVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTR--------TFTIHAVSREHEG 226
            VV          L    ++   ++ W   +  L  T R          TI  + +E  G
Sbjct: 161 SVV----------LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAG 210

Query: 227 LYRCLVSN 234
            Y+C VSN
Sbjct: 211 EYQCEVSN 218


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,426,465
Number of Sequences: 37866
Number of extensions: 977233
Number of successful extensions: 6899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 4785
Number of HSP's gapped (non-prelim): 1581
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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