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Search of human proteins with 154350220
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154350220 DNA polymerase iota [Homo sapiens]
(740 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154350220 DNA polymerase iota [Homo sapiens] 1479 0.0
gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens] 144 2e-34
gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens] 128 2e-29
gi|84043967 REV1-like isoform 2 [Homo sapiens] 99 2e-20
gi|7706681 REV1-like isoform 1 [Homo sapiens] 90 9e-18
gi|46370086 transcription factor 12 isoform c [Homo sapiens] 35 0.33
gi|46370084 transcription factor 12 isoform b [Homo sapiens] 35 0.33
gi|46370082 transcription factor 12 isoform a [Homo sapiens] 35 0.33
gi|46370080 transcription factor 12 isoform a [Homo sapiens] 35 0.33
gi|4507391 transcription factor 12 isoform b [Homo sapiens] 35 0.33
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 34 0.43
gi|93141214 sodium channel, voltage-gated, type II, alpha isofor... 34 0.56
gi|93141212 sodium channel, voltage-gated, type II, alpha isofor... 34 0.56
gi|93141210 sodium channel, voltage-gated, type II, alpha isofor... 34 0.56
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 33 0.73
gi|38788260 bromodomain PHD finger transcription factor isoform ... 33 0.96
gi|28559039 mediator complex subunit 1 [Homo sapiens] 33 1.2
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 32 1.6
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 32 2.1
gi|124248546 HHIP-like 2 [Homo sapiens] 32 2.1
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 32 2.8
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 32 2.8
gi|42544159 heat shock 105kD [Homo sapiens] 32 2.8
gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [... 31 3.6
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 31 4.7
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 31 4.7
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 31 4.7
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 31 4.7
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 31 4.7
gi|62988361 absent in melanoma 1 [Homo sapiens] 30 6.2
>gi|154350220 DNA polymerase iota [Homo sapiens]
Length = 740
Score = 1479 bits (3829), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL 60
MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
Sbjct: 1 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL 60
Query: 61 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN 120
DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
Sbjct: 61 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN 120
Query: 121 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG 180
GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
Sbjct: 121 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG 180
Query: 181 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP 240
HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
Sbjct: 181 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP 240
Query: 241 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI 300
NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
Sbjct: 241 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI 300
Query: 301 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD 360
SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
Sbjct: 301 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD 360
Query: 361 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV 420
GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
Sbjct: 361 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV 420
Query: 421 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK 480
NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
Sbjct: 421 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK 480
Query: 481 DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQ 540
DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQ
Sbjct: 481 DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQ 540
Query: 541 EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC 600
EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
Sbjct: 541 EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC 600
Query: 601 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP 660
EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
Sbjct: 601 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP 660
Query: 661 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV 720
NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
Sbjct: 661 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV 720
Query: 721 QKELLAEWKRAGSDFHIGHK 740
QKELLAEWKRAGSDFHIGHK
Sbjct: 721 QKELLAEWKRAGSDFHIGHK 740
>gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]
Length = 713
Score = 144 bits (364), Expect = 2e-34
Identities = 129/465 (27%), Positives = 207/465 (44%), Gaps = 61/465 (13%)
Query: 53 RVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYL-----VVTCNYEARKLGVKKLMNVR 107
RV+ VD+DCF+ QVE NP L++KP V Q ++ +YEAR GV + M
Sbjct: 7 RVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWAD 66
Query: 108 DAKEKCPQLVLVNGED------LTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMV 161
DAK+ CP L+L + LT+YRE S +V E++ F+ V+ER DE +VDLT V
Sbjct: 67 DAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFA-VIERASIDEAYVDLTSAV 125
Query: 162 EKRLQQLQSDELSA-------------------VTVSGHVYNNQSI-NLLDVLHI----- 196
++RLQ+LQ +SA TV Q + LD L I
Sbjct: 126 QERLQKLQGQPISADLLPSTYIEGLPQGPTTAEETVQKEGMRKQGLFQWLDSLQIDNLTS 185
Query: 197 ---RLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQH 253
+L VG+ I EMR A+ + G AG++ NK+LAKL G+ KPN+QT++ S
Sbjct: 186 PDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQ 245
Query: 254 LIHSLNHIKEIPGIGYKT-AKCLEALGINSVRDLQTFSPKILEKELGISVAQRIQKLSFG 312
L + I++I +G K A +E LGI + +L F+ L+ G + + G
Sbjct: 246 LFSQM-PIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRG 304
Query: 313 EDNSPVILSGPPQSFSEEDSFKKCSSEVEAKN------KIEELLASLLNRVCQDGRKPHT 366
++ PV P++ +F ++ + ++ + L L + D + T
Sbjct: 305 IEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRNDNDRVAT 364
Query: 367 VRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMVNVKMPF 426
++ R +K R C + + K+ ++D T ++ + + +
Sbjct: 365 QLVVSIRVQGDKRLSSLRRCCALTRYDAHKM---SHDAFT----VIKNCNTSGIQTEWSP 417
Query: 427 HLTLLSVCFCNLKALNTAKKGLIDYYL------MPSLSTTSRSGK 465
LT+L +C A + I +L +P + TS K
Sbjct: 418 PLTMLFLCATKFSASAPSSSTDITSFLSSDPSSLPKVPVTSSEAK 462
>gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]
Length = 870
Score = 128 bits (322), Expect = 2e-29
Identities = 102/370 (27%), Positives = 173/370 (46%), Gaps = 47/370 (12%)
Query: 52 SRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKE 111
S IVH+D+D FYA VEM NPELKDKP+ V ++ T NY AR+ GV+ M AK
Sbjct: 100 SNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKR 159
Query: 112 KCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSD 171
CPQL++V + +YR +S +V E+L ++ P + DE ++++T+ +E+R +
Sbjct: 160 LCPQLIIV-PPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDK 218
Query: 172 ELSAVTVSGHVYNN---QSINLL------------------------------------D 192
+ + V N+ + +N L
Sbjct: 219 RRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQ 278
Query: 193 VLHIRLLVGS---QIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP- 248
+L ++ G+ ++ E+R + + LT AG+A N +LAK+ S KPN Q +LP
Sbjct: 279 ILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPN 338
Query: 249 -ESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVAQRIQ 307
++ I L I+++ GIG T K L+ALGI + +L +L +
Sbjct: 339 RQAVMDFIKDL-PIRKVSGIGKVTEKMLKALGIITCTELYQ-QRALLSLLFSETSWHYFL 396
Query: 308 KLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTV 367
+S G ++ + G +S S E +F + + E + +EL + L + ++ K TV
Sbjct: 397 HISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTV 456
Query: 368 RLIIRRYSSE 377
+ ++ + E
Sbjct: 457 TIKLKNVNFE 466
>gi|84043967 REV1-like isoform 2 [Homo sapiens]
Length = 1250
Score = 98.6 bits (244), Expect = 2e-20
Identities = 97/388 (25%), Positives = 158/388 (40%), Gaps = 94/388 (24%)
Query: 44 VLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGV--------------------- 82
VL +P S I+HVD+DCF+ V + + P+LK KP+ V
Sbjct: 409 VLNSPRHQS-CIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLEW 467
Query: 83 ---QQKYL-------------------------------VVTCNYEARKLGVKKLMNVRD 108
Q K L + +C+YEAR+LG+K M
Sbjct: 468 QYYQNKILKGKADIPDSSLWENPDSAQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGH 527
Query: 109 AKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQL 168
AK+ CP L V D Y+E++ + E L ++ +E + DE VD+TE++ + +L
Sbjct: 528 AKQLCPNLQAVP-YDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAET--KL 584
Query: 169 QSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNK 228
DE A +R + +Q G+ SN
Sbjct: 585 TPDEF-------------------------------ANAVRMEIKDQTKCAASVGIGSNI 613
Query: 229 LLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQT 288
LLA++ + KP+ Q L PE I + +PG+G+ L +LGI + DLQ
Sbjct: 614 LLARMATRKAKPDGQYHLKPEEVDDFIRG-QLVTNLPGVGHSMESKLASLGIKTCGDLQY 672
Query: 289 FSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFK-KCSSEVEAKNKIE 347
+ L+KE G Q + + G D+ PV +S S E ++ + + EA+ +
Sbjct: 673 MTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLL 732
Query: 348 ELLASLLNRVCQDGRKPH--TVRLIIRR 373
L + R+ G K T+++++R+
Sbjct: 733 SLSEEIQRRLEATGMKGKRLTLKIMVRK 760
>gi|7706681 REV1-like isoform 1 [Homo sapiens]
Length = 1251
Score = 89.7 bits (221), Expect = 9e-18
Identities = 76/289 (26%), Positives = 129/289 (44%), Gaps = 38/289 (13%)
Query: 88 VVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVER 147
+ +C+YEAR+LG+K M AK+ CP L V D Y+E++ + E L ++ +E
Sbjct: 508 IASCSYEARQLGIKNGMFFGHAKQLCPNLQAVP-YDFHAYKEVAQTLYETLASYTHNIEA 566
Query: 148 LGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAE 207
+ DE VD+TE++ + +L DE A
Sbjct: 567 VSCDEALVDITEILAET--KLTPDEF-------------------------------ANA 593
Query: 208 MREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGI 267
+R + +Q G+ SN LLA++ + KP+ Q L PE I + +PG+
Sbjct: 594 VRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVDDFIRG-QLVTNLPGV 652
Query: 268 GYKTAKCLEALGINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSF 327
G+ L +LGI + DLQ + L+KE G Q + + G D+ PV +S
Sbjct: 653 GHSMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSV 712
Query: 328 SEEDSFK-KCSSEVEAKNKIEELLASLLNRVCQDGRKPH--TVRLIIRR 373
S E ++ + + EA+ + L + R+ G K T+++++R+
Sbjct: 713 SAEINYGIRFTQPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKIMVRK 761
>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
Length = 512
Score = 34.7 bits (78), Expect = 0.33
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 571 FFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLK 630
F S MQD N D SSS +S +PG G +S+S+MS Y N
Sbjct: 51 FASTFFMQDGTHNSSDLWSSSNGMS-----QPGFGGILGTSTSHMSQSSSYG----NLHS 101
Query: 631 DERISQGPKEPQGFHFTNSNPAVSAFH 657
+R+S P S P +S+FH
Sbjct: 102 HDRLSYPPHSVSPTDINTSLPPMSSFH 128
>gi|46370084 transcription factor 12 isoform b [Homo sapiens]
Length = 682
Score = 34.7 bits (78), Expect = 0.33
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 571 FFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLK 630
F S MQD N D SSS +S +PG G +S+S+MS Y N
Sbjct: 221 FASTFFMQDGTHNSSDLWSSSNGMS-----QPGFGGILGTSTSHMSQSSSYG----NLHS 271
Query: 631 DERISQGPKEPQGFHFTNSNPAVSAFH 657
+R+S P S P +S+FH
Sbjct: 272 HDRLSYPPHSVSPTDINTSLPPMSSFH 298
>gi|46370082 transcription factor 12 isoform a [Homo sapiens]
Length = 706
Score = 34.7 bits (78), Expect = 0.33
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 571 FFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLK 630
F S MQD N D SSS +S +PG G +S+S+MS Y N
Sbjct: 221 FASTFFMQDGTHNSSDLWSSSNGMS-----QPGFGGILGTSTSHMSQSSSYG----NLHS 271
Query: 631 DERISQGPKEPQGFHFTNSNPAVSAFH 657
+R+S P S P +S+FH
Sbjct: 272 HDRLSYPPHSVSPTDINTSLPPMSSFH 298
>gi|46370080 transcription factor 12 isoform a [Homo sapiens]
Length = 706
Score = 34.7 bits (78), Expect = 0.33
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 571 FFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLK 630
F S MQD N D SSS +S +PG G +S+S+MS Y N
Sbjct: 221 FASTFFMQDGTHNSSDLWSSSNGMS-----QPGFGGILGTSTSHMSQSSSYG----NLHS 271
Query: 631 DERISQGPKEPQGFHFTNSNPAVSAFH 657
+R+S P S P +S+FH
Sbjct: 272 HDRLSYPPHSVSPTDINTSLPPMSSFH 298
>gi|4507391 transcription factor 12 isoform b [Homo sapiens]
Length = 682
Score = 34.7 bits (78), Expect = 0.33
Identities = 28/87 (32%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 571 FFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLK 630
F S MQD N D SSS +S +PG G +S+S+MS Y N
Sbjct: 221 FASTFFMQDGTHNSSDLWSSSNGMS-----QPGFGGILGTSTSHMSQSSSYG----NLHS 271
Query: 631 DERISQGPKEPQGFHFTNSNPAVSAFH 657
+R+S P S P +S+FH
Sbjct: 272 HDRLSYPPHSVSPTDINTSLPPMSSFH 298
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 34.3 bits (77), Expect = 0.43
Identities = 47/206 (22%), Positives = 86/206 (41%), Gaps = 22/206 (10%)
Query: 527 VDQEVFKQLPVDIQEEILSG--KSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINP 584
+D+EVF+ DIQ+ +++G K+ + S C A + Q Q+ I+
Sbjct: 211 LDEEVFEG---DIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAA-------QAQEPQIDE 260
Query: 585 RDHLSSSKQVSSVSP-CEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQG 643
+ + K++ +V+ + + F S SS+K SY + K + + Q
Sbjct: 261 KKKSNFKKKMRTVATKSKEKSKKFTPPKSEKFSSKKKKSYQASAKAKLGVKANIVDDFQE 320
Query: 644 FHF-------TNSNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPD 696
+++ T + VS + PN E++F+ + T + +S + L EN+E D
Sbjct: 321 YNYGTMESYQTEAPRHVSGTNE-PN-PVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEID 378
Query: 697 SVDEKITFPSDIDPQVFYELPEAVQK 722
D + D+ FYE E K
Sbjct: 379 GRDSDLLVDGDLGEYDFYEYKEYEDK 404
>gi|93141214 sodium channel, voltage-gated, type II, alpha isoform 2
[Homo sapiens]
Length = 2005
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 30/133 (22%)
Query: 572 FSKKQMQDIPINPRDHLSSSKQ--VSSVSPCEPG------------TSGFNSSSSSYMSS 617
F +KQ I P + L++ K +S+ + E G TSG SS Y+
Sbjct: 1029 FVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVD 1088
Query: 618 QKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSH 677
+ DY +++N T + P F NL +E+ S + +S
Sbjct: 1089 ESDYMSFINNP----------------SLTVTVPIAVGESDFENLNTEEFSSESDMEESK 1132
Query: 678 KQTVATDSHEGLT 690
++ AT S EG T
Sbjct: 1133 EKLNATSSSEGST 1145
>gi|93141212 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 30/133 (22%)
Query: 572 FSKKQMQDIPINPRDHLSSSKQ--VSSVSPCEPG------------TSGFNSSSSSYMSS 617
F +KQ I P + L++ K +S+ + E G TSG SS Y+
Sbjct: 1029 FVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVD 1088
Query: 618 QKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSH 677
+ DY +++N T + P F NL +E+ S + +S
Sbjct: 1089 ESDYMSFINNP----------------SLTVTVPIAVGESDFENLNTEEFSSESDMEESK 1132
Query: 678 KQTVATDSHEGLT 690
++ AT S EG T
Sbjct: 1133 EKLNATSSSEGST 1145
>gi|93141210 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 33.9 bits (76), Expect = 0.56
Identities = 33/133 (24%), Positives = 52/133 (39%), Gaps = 30/133 (22%)
Query: 572 FSKKQMQDIPINPRDHLSSSKQ--VSSVSPCEPG------------TSGFNSSSSSYMSS 617
F +KQ I P + L++ K +S+ + E G TSG SS Y+
Sbjct: 1029 FVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVD 1088
Query: 618 QKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSH 677
+ DY +++N T + P F NL +E+ S + +S
Sbjct: 1089 ESDYMSFINNP----------------SLTVTVPIAVGESDFENLNTEEFSSESDMEESK 1132
Query: 678 KQTVATDSHEGLT 690
++ AT S EG T
Sbjct: 1133 EKLNATSSSEGST 1145
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 33.5 bits (75), Expect = 0.73
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 463 SGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLC- 521
SG+ + +D+ + T + +S E PL +T+ S+E+D PL
Sbjct: 2907 SGESAQPPEDSSPPASSESSSTRDSAVAISGADSRGILEEPLPSTS-SEEED----PLAG 2961
Query: 522 -SLPEGVDQEVFKQLPVDIQEEILSGK 547
SLPEGVD LP DI+ E+L +
Sbjct: 2962 ISLPEGVDPSFLAALPDDIRREVLQNQ 2988
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 33.1 bits (74), Expect = 0.96
Identities = 47/228 (20%), Positives = 87/228 (38%), Gaps = 25/228 (10%)
Query: 480 KDKETNRDFLPSGR---IESTRTRESPLDTTNFSKE--KDINEFPLCSLPEGVDQEVFKQ 534
K + +N+ FL + +ES R ++ +D +E KD NE S ++E F+
Sbjct: 540 KARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFED 599
Query: 535 LPVDIQEEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQV 594
++ + K+ + +G P + + N D+ +++
Sbjct: 600 QSLEKDSD---DKTPDDDPEQGKSEEPTEVG---------DKGNSVSANLGDNTTNATS- 646
Query: 595 SSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVS 654
SP E S +S D S + ++ E P+EP +SN + +
Sbjct: 647 EETSPSE------GRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKT-CESSNTSAT 699
Query: 655 AFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKI 702
PNL++ S +++ S A D G E+ P S+ E+I
Sbjct: 700 TTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEI 747
Score = 31.6 bits (70), Expect = 2.8
Identities = 45/201 (22%), Positives = 73/201 (36%), Gaps = 28/201 (13%)
Query: 444 AKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESP 503
AKKG ID P + ++ E+ KD E NR+ +E ++P
Sbjct: 562 AKKGDIDNVKSPEETEKDKN----------ETENDSKDAEKNREEFEDQSLEKDSDDKTP 611
Query: 504 LDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQEEILSGKSREKF--QGKGSVSCP 561
D K ++ E + + ++ + + S E +G+ V C
Sbjct: 612 DDDPEQGKSEEPTEVG----------DKGNSVSANLGDNTTNATSEETSPSEGRSPVGC- 660
Query: 562 LHASRGVLSFFSKKQM----QDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSS 617
L + + KK QD+P P SS ++ + +P N SSS SS
Sbjct: 661 LSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSN-SSSELNSS 719
Query: 618 QKDYSYYLDNRLKDERISQGP 638
Q + + D+ ER S P
Sbjct: 720 QSESAKAADDPENGERESHTP 740
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 32.7 bits (73), Expect = 1.2
Identities = 54/223 (24%), Positives = 85/223 (38%), Gaps = 25/223 (11%)
Query: 461 SRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPL 520
SR+ + K KD PK K+ + + S R P T K
Sbjct: 996 SRTPSNDGKSKDKP----PKRKKADTEGKSPSHSSSNRPFTPPTSTGG---SKSPGSAGR 1048
Query: 521 CSLPEGVDQEVFKQLPVDIQE-EILSGK--SREKFQGKGSVSCP------LHASRGVLSF 571
P GV ++ + I + ++ GK S ++ GSVS H+S S
Sbjct: 1049 SQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA 1108
Query: 572 FSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKD 631
+ +M+ + + SSS ++SS G+SG + S +S S K S +
Sbjct: 1109 STSGKMK----SSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLS 1164
Query: 632 ERISQGPKEPQG-----FHFTNSNPAVSAFHSFPNLQSEQLFS 669
S +PQG + + S P +S HS P S++L S
Sbjct: 1165 SGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLAS 1207
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 32.3 bits (72), Expect = 1.6
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 18/126 (14%)
Query: 595 SSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGF----HFTNSN 650
S +SP T+ S ++ S+K ++Y R D +S G ++S
Sbjct: 2498 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 2557
Query: 651 PAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATD-------------SHEGLTENREPDS 697
P + +FP+ + SR H+T SH +TD S E T + P S
Sbjct: 2558 PGSTHTTAFPDSTTTPGLSR-HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGS 2616
Query: 698 VDEKIT 703
D ++
Sbjct: 2617 TDTALS 2622
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 32.0 bits (71), Expect = 2.1
Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 2/145 (1%)
Query: 589 SSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTN 648
SSS SS S +S +SSSSS SS S+ ++L E + K+ +
Sbjct: 159 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAF 218
Query: 649 SNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDI 708
P S H+ + +S + N K E ++EP +T S
Sbjct: 219 KEP--SRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQ 276
Query: 709 DPQVFYELPEAVQKELLAEWKRAGS 733
D + + P E L+ KR S
Sbjct: 277 DKKAPSKRPPISDSEELSAKKRKKS 301
>gi|124248546 HHIP-like 2 [Homo sapiens]
Length = 724
Score = 32.0 bits (71), Expect = 2.1
Identities = 25/70 (35%), Positives = 33/70 (47%), Gaps = 6/70 (8%)
Query: 313 EDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIR 372
+ +S + SGP Q SE+ S KK +S +KN + RV PH VR R
Sbjct: 646 KSSSATLASGPAQGLSEKGSSKKLASPTSSKNTLRGPGTKKKARV-----GPH-VRQGKR 699
Query: 373 RYSSEKHYGR 382
R S + H GR
Sbjct: 700 RKSLKSHSGR 709
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 8/104 (7%)
Query: 472 DTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEV 531
DT++ FP K NR S ++ + L+ SK KD + Q+V
Sbjct: 122 DTYLGQFPDIK--NRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKV 179
Query: 532 FKQLPVDIQEEILSGKSR------EKFQGKGSVSCPLHASRGVL 569
F++ VD+QEE+ S SR F+ S+ H VL
Sbjct: 180 FEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVL 223
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 8/104 (7%)
Query: 472 DTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEV 531
DT++ FP K NR S ++ + L+ SK KD + Q+V
Sbjct: 122 DTYLGQFPDIK--NRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKV 179
Query: 532 FKQLPVDIQEEILSGKSR------EKFQGKGSVSCPLHASRGVL 569
F++ VD+QEE+ S SR F+ S+ H VL
Sbjct: 180 FEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVL 223
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 31.6 bits (70), Expect = 2.8
Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 27/174 (15%)
Query: 30 DVGAAASSQGVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVV 89
D+ A A + G++ Q LP+ + R++V VD+ QV + + K K LG +
Sbjct: 173 DMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLG 232
Query: 90 TCNYEAR-----------------KLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSY 132
N++ + K ++ L+ + EK +L+ N DL ++
Sbjct: 233 GKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDL----PLNI 288
Query: 133 KVTELLEEFSPVVERLGFDENFVDLTEMVEKRL------QQLQSDELSAVTVSG 180
+ ++ S + R F+E +L + +E L L+ +++SAV + G
Sbjct: 289 ECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVG 342
>gi|27881482 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I
[Homo sapiens]
Length = 925
Score = 31.2 bits (69), Expect = 3.6
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 136 ELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQS 170
+ L++F V GFDE DLT+ E++LQ+L+S
Sbjct: 565 DYLKDFFSNVRAAGFDEIEQDLTQRFEEKLQELES 599
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 30.8 bits (68), Expect = 4.7
Identities = 16/58 (27%), Positives = 26/58 (44%)
Query: 665 EQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAVQK 722
E++F+ + T + +S + L EN+E D D + D+ FYE E K
Sbjct: 296 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDK 353
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 30.8 bits (68), Expect = 4.7
Identities = 16/58 (27%), Positives = 26/58 (44%)
Query: 665 EQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAVQK 722
E++F+ + T + +S + L EN+E D D + D+ FYE E K
Sbjct: 335 EEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDK 392
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 30.8 bits (68), Expect = 4.7
Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 7/142 (4%)
Query: 573 SKKQMQDIPINPRDHLSSSKQ--VSSVSPCEPG-TSGFNSSSSSYMSSQKDYSYYLDNRL 629
S + Q+ ++ +++ S S++ VS P T+ + SS++D S+ L +
Sbjct: 337 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK 396
Query: 630 KDERISQGPKEP-QGFHFTNSNPAVSAFH---SFPNLQSEQLFSRNHTTDSHKQTVATDS 685
+ R Q E + +F+ +P S LQS + + + +SH + +DS
Sbjct: 397 SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 456
Query: 686 HEGLTENREPDSVDEKITFPSD 707
+ + +S + K + D
Sbjct: 457 QDSSRSKEDSNSTESKSSSEED 478
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 30.8 bits (68), Expect = 4.7
Identities = 29/142 (20%), Positives = 60/142 (42%), Gaps = 7/142 (4%)
Query: 573 SKKQMQDIPINPRDHLSSSKQ--VSSVSPCEPG-TSGFNSSSSSYMSSQKDYSYYLDNRL 629
S + Q+ ++ +++ S S++ VS P T+ + SS++D S+ L +
Sbjct: 321 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSK 380
Query: 630 KDERISQGPKEP-QGFHFTNSNPAVSAFH---SFPNLQSEQLFSRNHTTDSHKQTVATDS 685
+ R Q E + +F+ +P S LQS + + + +SH + +DS
Sbjct: 381 SESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDS 440
Query: 686 HEGLTENREPDSVDEKITFPSD 707
+ + +S + K + D
Sbjct: 441 QDSSRSKEDSNSTESKSSSEED 462
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 30.8 bits (68), Expect = 4.7
Identities = 23/118 (19%), Positives = 47/118 (39%), Gaps = 10/118 (8%)
Query: 438 LKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIEST 497
LK LN+ L Y+ + + + +G+ FK + + P K R++
Sbjct: 757 LKELNSYSSALSQYFFVREIFEQNLAGEVIFKFRQPEAHEKPSQK----------RVKKL 806
Query: 498 RTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQEEILSGKSREKFQGK 555
R ++ + S+E + E V++E +++ I EE+L + + K
Sbjct: 807 RKKQGSKEDMTRSEESISSGTSTARSVEEVEEENDQEMESFITEEVLGQQKKSPLHAK 864
>gi|62988361 absent in melanoma 1 [Homo sapiens]
Length = 1723
Score = 30.4 bits (67), Expect = 6.2
Identities = 28/147 (19%), Positives = 56/147 (38%), Gaps = 8/147 (5%)
Query: 441 LNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPKDKETNRDF-------LPSGR 493
LN + L+ + + S S HS +HME +P+ ++T D LP +
Sbjct: 888 LNKEQSNLLPDNSLKVFNFNSSSTSHSSLKSPSHMEKYPQKEKTKEDLDSRSNLHLPETK 947
Query: 494 I-ESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQEEILSGKSREKF 552
E ++ + ++ N + + P C+ + +FK D +
Sbjct: 948 FSELSKLKNDDMEKANHIESVIKSNLPNCANSDTDFMGLFKSSRYDPSISFSGMSLSDTM 1007
Query: 553 QGKGSVSCPLHASRGVLSFFSKKQMQD 579
+GSV L+ G + +S+ + +
Sbjct: 1008 TLRGSVQNKLNPRPGKVVIYSEPDVSE 1034
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,645,800
Number of Sequences: 37866
Number of extensions: 1329099
Number of successful extensions: 3636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3528
Number of HSP's gapped (non-prelim): 126
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.