Guide to the Human Genome
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Name: POLI Sequence: fasta or formatted (740aa) NCBI GI: 154350220
Description:

DNA polymerase iota

Referenced in:

DNA Polymerases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.3         32           3
 C cysteine            1.9         14           1
 D aspartate           5.7         42           3
 E glutamate           8.4         62           3
 F phenylalanine       4.1         30           2
 G glycine             5.5         41           3
 H histidine           3.0         22           1
 I isoleucine          4.2         31           2
 K lysine              7.3         54           2
 L leucine             9.9         73           2
 M methionine          2.4         18           1
 N asparagine          4.5         33           2
 P proline             5.3         39           2
 Q glutamine           5.0         37           2
 R arginine            4.3         32           2
 S serine             10.3         76           5
 T threonine           4.2         31           2
 V valine              7.2         53           2
 W tryptophan          0.3          2           1
 Y tyrosine            2.4         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA polymerase iota 
POLH                  0.082   DNA-directed DNA polymerase eta 
POLK                  0.071   DNA-directed DNA polymerase kappa 
REV1                  0.051   REV1-like isoform 2 
REV1                  0.045   REV1-like isoform 1 
TCF12                 0.007   transcription factor 12 isoform c 
TCF12                 0.007   transcription factor 12 isoform b 
TCF12                 0.007   transcription factor 12 isoform a 
TCF12                 0.007   transcription factor 12 isoform a 
TCF12                 0.007   transcription factor 12 isoform b 
COL11A1               0.006   alpha 1 type XI collagen isoform B preproprotein [Ho...
SCN2A                 0.006   sodium channel, voltage-gated, type II, alpha isofor...
SCN2A                 0.006   sodium channel, voltage-gated, type II, alpha isofor...
SCN2A                 0.006   sodium channel, voltage-gated, type II, alpha isofor...
HUWE1                 0.006   HECT, UBA and WWE domain containing 1 
BPTF                  0.006   bromodomain PHD finger transcription factor isoform ...
MED1                  0.006   mediator complex subunit 1 
MUC12                 0.005   PREDICTED: mucin 12 
MLLT3                 0.005   myeloid/lymphoid or mixed-lineage leukemia (trithor...
HHIPL2                0.005   HHIP-like 2 
AMPH                  0.005   amphiphysin isoform 2 
AMPH                  0.005   amphiphysin isoform 1 
HSPH1                 0.005   heat shock 105kD 
DDX58                 0.004   DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide RIG-I [...
COL11A1               0.004   alpha 1 type XI collagen isoform C preproprotein [Ho...
COL11A1               0.004   alpha 1 type XI collagen isoform A preproprotein [Ho...
DMP1                  0.004   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
DMP1                  0.004   dentin matrix acidic phosphoprotein 1 isoform 2 pre...
KIAA1529              0.004   hypothetical protein LOC57653 
AIM1                  0.003   absent in melanoma 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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