Guide to the Human Genome
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Name: POLH Sequence: fasta or formatted (713aa) NCBI GI: 5729982
Description:

DNA-directed DNA polymerase eta

Referenced in:

DNA Polymerases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.9         56           2
 C cysteine            2.4         17           2
 D aspartate           3.5         25           2
 E glutamate           6.3         45           2
 F phenylalanine       3.2         23           2
 G glycine             5.0         36           3
 H histidine           2.0         14           1
 I isoleucine          3.1         22           2
 K lysine              6.7         48           2
 L leucine             9.5         68           3
 M methionine          2.5         18           1
 N asparagine          3.4         24           2
 P proline             6.6         47           2
 Q glutamine           7.0         50           2
 R arginine            4.5         32           2
 S serine             10.9         78           3
 T threonine           6.3         45           2
 V valine              6.5         46           2
 W tryptophan          1.3          9           2
 Y tyrosine            1.4         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA-directed DNA polymerase eta 
POLI                  0.085   DNA polymerase iota 
POLK                  0.059   DNA-directed DNA polymerase kappa 
REV1                  0.031   REV1-like isoform 2 
REV1                  0.031   REV1-like isoform 1 
LOC100134138          0.013   PREDICTED: similar to mucin, partial 
LOC100133408          0.012   PREDICTED: similar to mucin 
MUC17                 0.012   mucin 17 
LOC100288540          0.011   PREDICTED: hypothetical protein XP_002342775 
POM121C               0.011   POM121 membrane glycoprotein (rat)-like 
ANKHD1                0.011   ankyrin repeat and KH domain containing 1 isoform 1 ...
ANKHD1-EIF4EBP3       0.011   ANKHD1-EIF4EBP3 protein 
POM121                0.010   nuclear pore membrane protein 121 
BAT2D1                0.010   HBxAg transactivated protein 2 
MUC5AC                0.010   mucin 5AC 
FLJ22184              0.010   PREDICTED: hypothetical protein FLJ22184 
LOC100131251          0.010   PREDICTED: hypothetical protein 
LOC100131251          0.010   PREDICTED: hypothetical protein 
MUC5B                 0.010   mucin 5, subtype B, tracheobronchial 
MUC21                 0.010   mucin 21 
MAP4                  0.010   microtubule-associated protein 4 isoform 4 
MAP4                  0.010   microtubule-associated protein 4 isoform 1 
CRTC3                 0.010   transducer of regulated CREB protein 3 isoform a [H...
SRRM2                 0.010   splicing coactivator subunit SRm300 
CRTC3                 0.009   transducer of regulated CREB protein 3 isoform b [H...
LOC100134147          0.009   PREDICTED: hypothetical protein 
NOLC1                 0.009   nucleolar and coiled-body phosphoprotein 1 
BCL9L                 0.009   B-cell CLL/lymphoma 9-like 
BCL9                  0.009   B-cell CLL/lymphoma 9 
MUC3A                 0.009   PREDICTED: mucin 3A, cell surface associated, parti...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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