Guide to the Human Genome
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Search of human proteins with 154146231

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154146231 DMRT-like family A2 [Homo sapiens]
         (542 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154146231 DMRT-like family A2 [Homo sapiens]                      1087   0.0  
gi|170763515 DMRT-like family A1 [Homo sapiens]                       275   8e-74
gi|11056048 doublesex and mab-3 related transcription factor 3 [...   149   8e-36
gi|62241026 doublesex and mab-3 related transcription factor 1 [...   124   2e-28
gi|195947401 doublesex and mab-3 related transcription factor 2 ...   117   3e-26
gi|5729806 doublesex and mab-3 related transcription factor 2 is...   117   3e-26
gi|153945850 doublesex and mab-3 related transcription factor 2 ...   117   3e-26
gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [...   100   6e-21
gi|94536830 DMRT-like family C2 [Homo sapiens]                         86   1e-16
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    76   7e-14
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      72   2e-12
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                68   2e-11
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    65   2e-10
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    65   2e-10
gi|153070260 myristoylated alanine-rich protein kinase C substra...    65   2e-10
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    62   1e-09
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    62   1e-09
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    62   1e-09
gi|126352446 elastin isoform d precursor [Homo sapiens]                60   4e-09
gi|126352322 elastin isoform c precursor [Homo sapiens]                60   4e-09
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    60   7e-09
gi|24432032 zinc finger protein 503 [Homo sapiens]                     59   9e-09
gi|119395716 forkhead box C1 [Homo sapiens]                            59   1e-08
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     59   1e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                57   3e-08
gi|126352608 elastin isoform e precursor [Homo sapiens]                56   1e-07
gi|126352440 elastin isoform a precursor [Homo sapiens]                56   1e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      56   1e-07
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          56   1e-07
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       55   1e-07

>gi|154146231 DMRT-like family A2 [Homo sapiens]
          Length = 542

 Score = 1087 bits (2810), Expect = 0.0
 Identities = 542/542 (100%), Positives = 542/542 (100%)

Query: 1   MELRSELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRA 60
           MELRSELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRA
Sbjct: 1   MELRSELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRA 60

Query: 61  AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA 120
           AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA
Sbjct: 61  AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA 120

Query: 121 QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180
           QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA
Sbjct: 121 QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180

Query: 181 AGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSE 240
           AGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSE
Sbjct: 181 AGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSE 240

Query: 241 NGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA 300
           NGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA
Sbjct: 241 NGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA 300

Query: 301 PAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAA 360
           PAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAA
Sbjct: 301 PAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAA 360

Query: 361 GLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLL 420
           GLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLL
Sbjct: 361 GLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLL 420

Query: 421 AGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGL 480
           AGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGL
Sbjct: 421 AGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGL 480

Query: 481 AFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGPMVNGAPE 540
           AFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGPMVNGAPE
Sbjct: 481 AFMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGPMVNGAPE 540

Query: 541 KQ 542
           KQ
Sbjct: 541 KQ 542


>gi|170763515 DMRT-like family A1 [Homo sapiens]
          Length = 504

 Score =  275 bits (703), Expect = 8e-74
 Identities = 207/520 (39%), Positives = 261/520 (50%), Gaps = 79/520 (15%)

Query: 8   PSVPGAATAAAATATGPPV----ASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEK 63
           P  P  A    +    PP      S+   AAAAAAAA+   S +GG    P L       
Sbjct: 28  PPPPSPALPVPSGMQVPPAFLRPPSLFLRAAAAAAAAAAATSGSGGCPPAPGLESGVGAV 87

Query: 64  ---YPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA 120
              YPRTPKCARCRNHGVVSALKGHKR+CRW+DC CAKCTLIAERQRVMAAQVALRRQQA
Sbjct: 88  GCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQA 147

Query: 121 QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180
           QEE+EAR LQ L     GL+        PP            A GGG  A  P  TGG A
Sbjct: 148 QEESEARGLQRLL--CSGLSW-------PPGGR---------ASGGGGRAENPQSTGGPA 189

Query: 181 AGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSP-DGADSGPG---TSSPEVRPG 236
           AGA      L++         +  +   P     +  S  +   +G     + S ++  G
Sbjct: 190 AGAALGLGALRQASGSATPAFEVFQQDYPEEKQEQKESKCESCQNGQEELISKSHQLYLG 249

Query: 237 SGSENGD--GESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADK 294
           S S +    G+   GS ++  S +         G   GGEE SP S S    ESG+E++ 
Sbjct: 250 SSSRSNGVIGKQSIGSSISEYSNKPDSILSPHPGEQSGGEE-SPRSLSSSDLESGNESEW 308

Query: 295 EEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHH 354
            +   A    L   S  R R PLDILT++FP +RR  LE +L+ C GDVVQAIEQVLN  
Sbjct: 309 VKDLTATKASLPTVSS-RPRDPLDILTKIFPNYRRSRLEGILRFCKGDVVQAIEQVLN-- 365

Query: 355 RGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
                   G    PD   +  +   ++    R  + + A                     
Sbjct: 366 --------GKEHKPDNRNLANSEELENTAFQRASSFSLAGI------------------- 398

Query: 415 HHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAA 474
                          G+L ++SAFSPLQ  ++ +G D+  Y +   +G+SPLRLAYS+A 
Sbjct: 399 -------------GFGTLGNKSAFSPLQTTSASYGGDSSLYGVNPRVGISPLRLAYSSA- 444

Query: 475 AHSRGLA-FMAPYSTAGLVPTLGFRPPMDYAFSDLMRDRS 513
              RGL+ FM+PY T GLVPTL FRP +DYAFS ++RD S
Sbjct: 445 --GRGLSGFMSPYLTPGLVPTLPFRPALDYAFSGMIRDSS 482


>gi|11056048 doublesex and mab-3 related transcription factor 3
           [Homo sapiens]
          Length = 472

 Score =  149 bits (375), Expect = 8e-36
 Identities = 141/429 (32%), Positives = 181/429 (42%), Gaps = 84/429 (19%)

Query: 50  LLRGPPLLLRAAEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVM 109
           L  G P+         RTPKCARCRNHGV+S LKGHKRYCR+KDC C KC LI ERQRVM
Sbjct: 9   LYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVM 68

Query: 110 AAQVALRRQQAQEENEA---RELQLLYG-TAEGLALAA--------ANGIIPPRPAYEVF 157
           AAQVALRRQQA E  E+     L+ L G    G A+AA         +   PPRPA E+ 
Sbjct: 69  AAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAEL- 127

Query: 158 GSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPL 217
                       A A A         G  +A+L K DL  + L       +      +  
Sbjct: 128 ------------AAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADN-----TEVF 170

Query: 218 SPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDS 277
           S    D     SSP+V    G        F+       S E GG    +    GG  E  
Sbjct: 171 SDKDTDQ---RSSPDVAKSKG-------CFTPESPEIVSVEEGGY---AVQKNGGNPESR 217

Query: 278 PGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQ 337
           P S      ++    +   G  +    L        R PL++L ++FP  +  VLEL+L+
Sbjct: 218 PDSPKCHAEQNHLLIEGPSGTVSLPFSL-----KANRPPLEVLKKIFPNQKPTVLELILK 272

Query: 338 GCGGDVVQAIEQVLNHHRGGLAAGLGPAAP----------------------PDKAAVGA 375
           GCGGD+V A+E +L+       A    A P                        K +VG+
Sbjct: 273 GCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGS 332

Query: 376 AAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSR 435
           A    D      D++           +P+PL AGP  PP  +P       P  L +  +R
Sbjct: 333 AFRVPDTLRFSADSSNV---------VPSPL-AGPLQPPFPQP----PRYPLMLRNTLAR 378

Query: 436 SAFSPLQPN 444
           S  SP  PN
Sbjct: 379 SQSSPFLPN 387


>gi|62241026 doublesex and mab-3 related transcription factor 1
           [Homo sapiens]
          Length = 373

 Score =  124 bits (312), Expect = 2e-28
 Identities = 65/119 (54%), Positives = 74/119 (62%), Gaps = 3/119 (2%)

Query: 5   SELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKY 64
           SE P  PG      A   G    ++   A+ ++A  S   S  GG   G   L   ++K 
Sbjct: 14  SEAPHAPGVPPQGRAGGFGKASGALVGAASGSSAGGS---SRGGGSGSGASDLGAGSKKS 70

Query: 65  PRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEE 123
           PR PKCARCRNHG  S LKGHKR+C W+DC C KC LIAERQRVMAAQVALRRQQAQEE
Sbjct: 71  PRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQEE 129


>gi|195947401 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score =  117 bits (293), Expect = 3e-26
 Identities = 62/118 (52%), Positives = 69/118 (58%), Gaps = 11/118 (9%)

Query: 8   PSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRT 67
           P +PG           PP+A  AS A         P   AGG             K  RT
Sbjct: 72  PGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTP---AGGGAE--------PRKLSRT 120

Query: 68  PKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENE 125
           PKCARCRNHGVVS LKGHKR+CRW+DC CA C L+ ERQRVMAAQVALRRQQA E+ +
Sbjct: 121 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKK 178



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 22/82 (26%), Positives = 25/82 (30%), Gaps = 5/82 (6%)

Query: 206 PGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPG 265
           P  P PPP      D  D   G        G G E G      G P  R   +       
Sbjct: 34  PPGPSPPPADGDCEDDEDDD-GVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAP 92

Query: 266 SAGPGGGGEED----SPGSASP 283
            A P G G  +    + G A P
Sbjct: 93  QASPAGTGPRERCTPAGGGAEP 114


>gi|5729806 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score =  117 bits (293), Expect = 3e-26
 Identities = 62/118 (52%), Positives = 69/118 (58%), Gaps = 11/118 (9%)

Query: 8   PSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRT 67
           P +PG           PP+A  AS A         P   AGG             K  RT
Sbjct: 72  PGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTP---AGGGAE--------PRKLSRT 120

Query: 68  PKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENE 125
           PKCARCRNHGVVS LKGHKR+CRW+DC CA C L+ ERQRVMAAQVALRRQQA E+ +
Sbjct: 121 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKK 178



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 22/82 (26%), Positives = 25/82 (30%), Gaps = 5/82 (6%)

Query: 206 PGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPG 265
           P  P PPP      D  D   G        G G E G      G P  R   +       
Sbjct: 34  PPGPSPPPADGDCEDDEDDD-GVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAP 92

Query: 266 SAGPGGGGEED----SPGSASP 283
            A P G G  +    + G A P
Sbjct: 93  QASPAGTGPRERCTPAGGGAEP 114


>gi|153945850 doublesex and mab-3 related transcription factor 2
           isoform 2 [Homo sapiens]
          Length = 561

 Score =  117 bits (293), Expect = 3e-26
 Identities = 62/118 (52%), Positives = 69/118 (58%), Gaps = 11/118 (9%)

Query: 8   PSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRT 67
           P +PG           PP+A  AS A         P   AGG             K  RT
Sbjct: 72  PGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTP---AGGGAE--------PRKLSRT 120

Query: 68  PKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENE 125
           PKCARCRNHGVVS LKGHKR+CRW+DC CA C L+ ERQRVMAAQVALRRQQA E+ +
Sbjct: 121 PKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKK 178



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 22/82 (26%), Positives = 25/82 (30%), Gaps = 5/82 (6%)

Query: 206 PGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPG 265
           P  P PPP      D  D   G        G G E G      G P  R   +       
Sbjct: 34  PPGPSPPPADGDCEDDEDDD-GVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAP 92

Query: 266 SAGPGGGGEED----SPGSASP 283
            A P G G  +    + G A P
Sbjct: 93  QASPAGTGPRERCTPAGGGAEP 114


>gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
           [Homo sapiens]
          Length = 342

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 56/121 (46%), Positives = 66/121 (54%), Gaps = 6/121 (4%)

Query: 61  AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA 120
           A+K  RTPKC+RCRNHG +  +KGH   CRWK CLC KC LI+ERQ++MAAQ  L+ Q A
Sbjct: 2   ADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAA 61

Query: 121 QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180
           +EE EA         A G A AA      P P      S+     G P   A  G  G A
Sbjct: 62  EEEQEAALCAQGPKQASGAAAAA------PAPVPVPAASLRPLSPGTPSGDADPGPEGRA 115

Query: 181 A 181
           A
Sbjct: 116 A 116


>gi|94536830 DMRT-like family C2 [Homo sapiens]
          Length = 367

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 39/54 (72%), Positives = 44/54 (81%)

Query: 66  RTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQ 119
           R+P CARCRNHGV + LKGHKR C ++ C C KC LI ER+RVMAAQVALRRQQ
Sbjct: 38  RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 113/405 (27%), Positives = 151/405 (37%), Gaps = 64/405 (15%)

Query: 140 ALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGG--AAGAGGSEAKLQKFDLFP 197
           A AA +  + PR   EV  +   A G    +G+PAG  G   AA A G+     +     
Sbjct: 35  ASAAHHHHLAPRTP-EVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG 93

Query: 198 KTLLQAGRPGSPLPP-PVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARAS 256
           +     G P  P PP P +PL P    +GP   + ++RP       +G + S +P+  A+
Sbjct: 94  RARPGGGGPQRPGPPSPRRPLVP----AGPAPPAAKLRPPP-----EGSAGSCAPVPAAA 144

Query: 257 KEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTP 316
             A G  P  AGP        P   + L + +G       G   P PG G  +GP     
Sbjct: 145 AVAAGPEPAPAGPA------KPAGPAALAARAGPGPGPGPGPG-PGPGPGKPAGPGAAQT 197

Query: 317 LDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAA 376
           L+    +   H      + L   G   +  + +         A G     PP    VGAA
Sbjct: 198 LNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-------APGTVIQTPP---FVGAA 247

Query: 377 AAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHH---RPLLAGAMAPGALGSLS 433
           A    A PS   AA A AA A  P  P P  A  A PP H    P  A A+ P       
Sbjct: 248 APPAPAAPSP-PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP------- 299

Query: 434 SRSAFSPLQPNASHFGADAGAYP-----LGAPLGLSPLRLAYSAAAAHSRGLAFMAPYST 488
                    P A+  G  AGA P      G P G+S      +AAAA + G+   +P   
Sbjct: 300 ---------PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350

Query: 489 AGLVPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKEPTYGGGLYGP 533
               P          A   L     A+ AA++   PT  G L  P
Sbjct: 351 VQAAPP---------AAQTLAASGPASTAASMVIGPTMQGALPSP 386



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 46/179 (25%), Positives = 66/179 (36%), Gaps = 21/179 (11%)

Query: 197 PKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARAS 256
           P     A  P  P P P     P G  +GP T++P V P + ++NG     + +P   A 
Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320

Query: 257 KEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA-PAPGLGGGSGPRQRT 315
             AG S  G  GPG      +PG          +E+ K   +AA PA      SGP    
Sbjct: 321 GPAGVS--GQPGPGAAAAAPAPGVK--------AESPKRVVQAAPPAAQTLAASGPASTA 370

Query: 316 PLDIL----------TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP 364
              ++              P    G    + +G  G V Q++ +       G+ A L P
Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP 429



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 42/156 (26%), Positives = 56/156 (35%), Gaps = 20/156 (12%)

Query: 148 IPPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGR 205
           +PP  A +  GS  AA    P AG PAG  G  G   A  + A   K +  PK ++QA  
Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE-SPKRVVQAA- 354

Query: 206 PGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPG 265
                PP  + L    A SGP +++  +  G   +          P   A        P 
Sbjct: 355 -----PPAAQTL----AASGPASTAASMVIGPTMQ-------GALPSPAAVPPPAPGTPT 398

Query: 266 SAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAP 301
               G  G      S +P  + SG  A       AP
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAP 434



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 93/400 (23%), Positives = 123/400 (30%), Gaps = 61/400 (15%)

Query: 6   ELPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYP 65
           + P   GAA   A  A  PP    A   AA AAA   P      L R P          P
Sbjct: 239 QTPPFVGAAAPPAPAAPSPP---AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295

Query: 66  RTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENE 125
             P  A  +N G   A               A        Q    A  A      + E+ 
Sbjct: 296 AVPPPAAAQNGGSAGAAPA--------PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347

Query: 126 ARELQLLYGTAEGLALA-----AANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180
            R +Q     A+ LA +     AA+ +I P     +           P  G P G   GA
Sbjct: 348 KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPP---PAPGTPTGLPKGA 404

Query: 181 AGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGS--- 237
           AG     A  Q     P T   +G   +  P  + P  P    +     + ++ PG    
Sbjct: 405 AG-----AVTQSLSRTP-TATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLV 458

Query: 238 GSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEG 297
            SENG         LA+   +A      +  P       +P SA P+           + 
Sbjct: 459 RSENGQLLMIPQQALAQMQAQAHAQPQTTMAP----RPATPTSAPPV-----------QI 503

Query: 298 EAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGG 357
               APG       RQ TP  I+ +V            LQ   G   Q +          
Sbjct: 504 STVQAPGT--PIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLV---------- 551

Query: 358 LAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAA 397
               LG AA    A++G A A     P R    A   ++A
Sbjct: 552 ----LGGAA--QTASLGTATAVQTGTPQRTVPGATTTSSA 585


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 91/337 (27%), Positives = 112/337 (33%), Gaps = 78/337 (23%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRP 206
            PP PA E          G PG   P G  G  G  G  G   +      FP     +G P
Sbjct: 927  PPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG----FPGLPGPSGEP 982

Query: 207  GSPLPP-------PVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEA 259
            G   P        P  P+ P G    PG S  E  PG+    G      GSP A+  +  
Sbjct: 983  GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGR----DGSPGAKGDR-- 1036

Query: 260  GGSCPGSAGPGGG-GEEDSPGSASPLGSESGSEADKEEGEAAPAPGLG--------GGSG 310
                 G  GP G  G   +PG+  P+G    S    E G A PA  +G        G  G
Sbjct: 1037 -----GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 311  PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP 368
            PR                         G  G+  +  ++ +  HRG  GL    GP   P
Sbjct: 1092 PR-------------------------GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 369  DKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL----------QAGPAAPPHHRP 418
             +   G + A+  A P     +A A    G  GLP P+           AGP  PP    
Sbjct: 1127 GEQ--GPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP---- 1180

Query: 419  LLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAY 455
                   PG  G  S+   FS L         D G Y
Sbjct: 1181 --GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRY 1215



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 89/319 (27%), Positives = 106/319 (33%), Gaps = 36/319 (11%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGS 208
            P  PA          D G PG   PAG  G     G   AK +  D   K       P  
Sbjct: 786  PSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG 845

Query: 209  PLPPPVKPLSPDGADSGPGTSSPEVRPGS----------GSENGDGESFSGSPLARASKE 258
            P  PP  P+   GA    G       PG+          G     G +    P   A KE
Sbjct: 846  PAGPP-GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904

Query: 259  AGGSCPGSAGPGG-GGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPR--QRT 315
             G    G  GP G  GE   PG   P G +    AD   G A   PG  G +G R     
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG-APGTPGPQGIAGQRGVVGL 963

Query: 316  PLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPDKAAV 373
            P     R FPG         L G  G+  +      +  RG  G     G A PP ++  
Sbjct: 964  PGQRGERGFPG---------LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR 1014

Query: 374  GAAAAADDAWPSRVDAAAA--------AAAAAGGPGLP-APLQAGPAAPPHHRPLLAGAM 424
              A  A+ + P R  +  A         A   G PG P AP   GPA     R     A 
Sbjct: 1015 EGAPGAEGS-PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAG 1073

Query: 425  APGALGSLSSRSAFSPLQP 443
              G +G + +R    P  P
Sbjct: 1074 PAGPVGPVGARGPAGPQGP 1092



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 97/346 (28%), Positives = 114/346 (32%), Gaps = 73/346 (21%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPP-PVKPLSPDGA 222
           G PGA   AG  G  G  GA G   K             AG  G P PP  V P   DG 
Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGK-------------AGERGVPGPPGAVGPAGKDGE 615

Query: 223 DSGPGTSSPEVRPGSGSENGDGES--FSG-----SPLARASKEAGGSCPGSAG------- 268
               G   P    G   E G   S  F G      P   A K      PG  G       
Sbjct: 616 AGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675

Query: 269 ------PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGP--RQRTPLDIL 320
                 PG  G +  PG A P G+      D  +G+A  APG  G  G    Q  P +  
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG-APGAPGSQGAPGLQGMPGERG 734

Query: 321 TRVFPGHRRGVLELVLQGCGG----DVVQAIEQVL----------NHHRGGLAAGLGP-- 364
               PG +    +   +G  G    D V+ +   +          +    G +   GP  
Sbjct: 735 AAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794

Query: 365 --AAPPDKAAVGAAAAADDAWPSRVDAAAAA------AAAAGGPGLPAPLQAGPAAPPHH 416
              AP D+   G    A  A P   D    A      A A G  G P P  AGPA PP  
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP--AGPAGPPGP 852

Query: 417 RPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLG 462
              +    APGA G+  S        P A+ F   AG      P G
Sbjct: 853 ---IGNVGAPGAKGARGSAG-----PPGATGFPGAAGRVGPPGPSG 890



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 90/335 (26%), Positives = 113/335 (33%), Gaps = 51/335 (15%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
           G PG   P G  G  G  G GG+ A    +    K+       G  +P P+ P  P G  
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKST-----GGISVPGPMGPSGPRGLP 190

Query: 224 SGPGTSSPEVRPGSGSENGD-------GESFSGSPLARASKEAGGSCPGSAG----PGGG 272
             PG   P+   G   E G+       G      P  +   +     PG  G    PG  
Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250

Query: 273 GEEDSPGSA---SPLGSESGSEADKEEGEAAPAPGLGGGSGPRQR-TPLDILTRVFPGHR 328
           G    PG+A      G    S  D  +G+A PA   G    P +   P  +  R  PG R
Sbjct: 251 GARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGER 310

Query: 329 RGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVD 388
                    G  G+              G     GPA PP     GA  A  +A P    
Sbjct: 311 GRPGAPGPAGARGNDGAT-------GAAGPPGPTGPAGPP--GFPGAVGAKGEAGPQGPR 361

Query: 389 AAAAAAAAAGGPGLPAPL-QAGPAAPP-----------HHRPLLAGAMA-PGALGSLSSR 435
            +       G PG P P   AGPA  P           +  P +AGA   PGA G    +
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421

Query: 436 SAFSPLQP--NASHFGA-----DAGAYPLGAPLGL 463
               P  P  N+   GA     D GA     P+G+
Sbjct: 422 GPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGV 456



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/326 (27%), Positives = 108/326 (33%), Gaps = 71/326 (21%)

Query: 149 PPRPAYEVFGSVCAADGGGPGAGAPAGTGGG------------AAGAGGSEAKLQKFDLF 196
           PP PA E        + G  G   P G  GG            A   G +  +       
Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518

Query: 197 PK-TLLQAGRPGSPLPPPVKPLS-------PDGADSGPGTSSPEVRPG----------SG 238
           PK +  +AGRPG    P  K L+       PDG    PG +  + RPG          +G
Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578

Query: 239 SENGDGESFSGSPLARASKEAGGSCPGSAGPGG----GGEEDSPGSASPLGSESGSEADK 294
                G   +     +A +      PG+ GP G     G +  PG A P G         
Sbjct: 579 VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG--------- 629

Query: 295 EEGEAAPA--PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLN 352
           E GE  PA  PG  G  GP             PG      E   QG  GD+         
Sbjct: 630 ERGEQGPAGSPGFQGLPGPAGP----------PGEAGKPGE---QGVPGDLGAPGPSGAR 676

Query: 353 HHRG-----GLAAGLGPAAPPD-KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA-P 405
             RG     G+    GPA P     A G   A  DA       A  A  + G PGL   P
Sbjct: 677 GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA------GAPGAPGSQGAPGLQGMP 730

Query: 406 LQAGPAAPPHHRPLLAGAMAPGALGS 431
            + G A  P  +     A   GA GS
Sbjct: 731 GERGAAGLPGPKGDRGDAGPKGADGS 756



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 83/298 (27%), Positives = 88/298 (29%), Gaps = 55/298 (18%)

Query: 150 PRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPG 207
           P PA            G PG   PAG  G  GA GA G EA  Q            G PG
Sbjct: 316 PGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKG-EAGPQGPRGSEGPQGVRGEPG 374

Query: 208 SPLPPPVK-PLSPDGADSGPGTSSPEVRPG-------SGSENGDGESFSGSPLARASKEA 259
            P P     P    GAD  PG       PG        G+    G    G P        
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434

Query: 260 GGSCPGSAGPGGGGEEDSP----GSASPLGSESGSEADKEEGEAA--PAPGLGGGSGPRQ 313
               PGS G  G   E  P    G   P G E    A  E G       PG  GG G   
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPG--- 491

Query: 314 RTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAV 373
                  +R FPG           G  G    A          G     GPA P  K + 
Sbjct: 492 -------SRGFPG---------ADGVAGPKGPA----------GERGSPGPAGP--KGSP 523

Query: 374 GAAAAADDAWPSRVDAAAAAAAAAGGPGLPAP-LQAGPAAPPHHRPLLAGAMAPGALG 430
           G A    +A          A    G PG P P  + GP  P            PGA G
Sbjct: 524 GEAGRPGEA------GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 110/411 (26%), Positives = 130/411 (31%), Gaps = 109/411 (26%)

Query: 164  DGGGPGA----GAPA--GTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-------L 210
            D G PGA    GAP   G  G    AG    K  + D  PK     G  GSP       L
Sbjct: 711  DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPK-----GADGSPGKDGVRGL 765

Query: 211  PPPVKPLSPDGADSGPGTSSPEVRPG-SGSENGDGE----------SFSGSPLARASKEA 259
              P+ P  P GA    G S P    G +G+    G+           F+G P A     A
Sbjct: 766  TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825

Query: 260  GGSC-----------PGSAGPGGG----GEEDSPGSASPLGSESGSEADKEEGEAAPA-- 302
             G             PG AGP G     G   +PG+    GS     A    G A     
Sbjct: 826  KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885

Query: 303  PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGL 362
            PG  G +GP             PG      +   +G  G+   A          G    +
Sbjct: 886  PGPSGNAGP-------------PGPPGPAGKEGGKGPRGETGPA----------GRPGEV 922

Query: 363  GPAAPPDKA-------AVGAAAAADDAWPSRVDAAAAAAAAAGG------PGLPAPL--- 406
            GP  PP  A       A G A A     P  +          G       PGLP P    
Sbjct: 923  GPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982

Query: 407  -QAGPAAPPHHR--------PLLAGAM-------APGALGSLSSRSAFSPLQPNASHFGA 450
             + GP+     R        P LAG         APGA GS     +     P A     
Sbjct: 983  GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGS-----PGAKGDRG 1037

Query: 451  DAG-AYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPP 500
            + G A P GAP           A  +  RG     P   AG V  +G R P
Sbjct: 1038 ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGET--GPAGPAGPVGPVGARGP 1086



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 58/247 (23%), Positives = 77/247 (31%), Gaps = 48/247 (19%)

Query: 206 PGSPLPP-PVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCP 264
           PG+ +P     P+ PDG++      SP  +  +G E   G++    P   A        P
Sbjct: 82  PGAEVPEGECCPVCPDGSE------SPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP 135

Query: 265 GSAG----PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDIL 320
           G  G    PG  G    PG       +     D++       PG  G SGPR        
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRG------- 188

Query: 321 TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPP-------DKAAV 373
               PG          QG  G+  +           G +  +GP  PP       D    
Sbjct: 189 ---LPGPPGAPGPQGFQGPPGEPGEP----------GASGPMGPRGPPGPPGKNGDDGEA 235

Query: 374 GAAAAADDAWPSRVDAAAAAAAAAGGPGLP----------APLQAGPAAPPHHRPLLAGA 423
           G      +  P     A      AG PG+           A   AGPA P          
Sbjct: 236 GKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295

Query: 424 MAPGALG 430
            APG +G
Sbjct: 296 GAPGQMG 302


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 93/316 (29%), Positives = 112/316 (35%), Gaps = 69/316 (21%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPP-PVKPLSPDGADS 224
           G PG   P G GG     G                 + G PG P PP P  P   DG + 
Sbjct: 717 GPPGVPGPPGPGGSPGLPG-----------------EIGFPGKPGPPGPTGPPGKDGPNG 759

Query: 225 GPGTSSPEVRPGSGSENG-------DGESFSGSPLARASKEAGGSCPGSAG-PGGGGEED 276
            PG    +  PG   E+G        GE        R  ++     PG+ G PG  GE+ 
Sbjct: 760 PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819

Query: 277 SPGSASPLGSESGSEADK-EEGEAAPA--PGLGGGSGPRQRTPLDILTRVFPGHRRGVLE 333
             G    LG   G + D+ E+GEA PA  PGL G             T +F  H R   E
Sbjct: 820 DQGEKGELGL-PGLKGDRGEKGEAGPAGPPGLPG------------TTSLFTPHPRMPGE 866

Query: 334 LVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAA 393
              +G  GD     E  L    G L    GP  PP     GA            + A  A
Sbjct: 867 QGPKGEKGDPGLPGEPGLQGRPGELGP-QGPTGPP-----GAKGQ---------EGAHGA 911

Query: 394 AAAAGGPGLPAPLQA-GPAAPPHH--RPLLAGAMAP----GALGSLSSRSAFSPLQPNAS 446
             AAG PG P  + A GP+ PP     P L G        G  G+     +  P+ P   
Sbjct: 912 PGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-- 969

Query: 447 HFGADAGAYPLGAPLG 462
               D GA  L  P G
Sbjct: 970 ---GDPGAPGLPGPPG 982



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 85/315 (26%), Positives = 111/315 (35%), Gaps = 79/315 (25%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG     G  G  G AG  G       F   P+           +P    P    G  
Sbjct: 828  GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR-----------MPGEQGPKGEKGDP 876

Query: 224  SGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGSAS 282
              PG    + RPG     G     +G P A+  + A G+ PG+AG PG  G   +PG + 
Sbjct: 877  GLPGEPGLQGRPGELGPQGP----TGPPGAKGQEGAHGA-PGAAGNPGAPGHVGAPGPSG 931

Query: 283  PLGS-----------ESGSEADK----EEGEAAP--------APGLGGGSG------PRQ 313
            P GS           + G   +K    EEG   P        APGL G  G      P  
Sbjct: 932  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGL 991

Query: 314  R----TPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPD 369
            R     P  + T+   G  RG     L G          Q +   RG  A G+ P +P  
Sbjct: 992  RGSPGLPGPLGTKAACGKVRGSENCALGG----------QCVKGDRG--APGI-PGSPGS 1038

Query: 370  KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPA----AP-------PHHRP 418
            +   G   A     PS       +  + G PG P P   GPA    AP       P  +P
Sbjct: 1039 RGDPGIGVAGPPG-PSGPPGDKGSPGSRGLPGFPGP--QGPAGRDGAPGNPGERGPPGKP 1095

Query: 419  LLAGAMAPGALGSLS 433
             L+  ++PG +  L+
Sbjct: 1096 GLSSLLSPGDINLLA 1110



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/173 (30%), Positives = 56/173 (32%), Gaps = 52/173 (30%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG   P G  G  G  G  G E K              GR G P PP        G  
Sbjct: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGK-------------EGRDGKPGPP-----GEPGKA 1260

Query: 224  SGPGTSSPEVR---PGSGSENGDGESFSGSPLARASKEAGG-----SCPGSAG------- 268
              PG   PE     PG     GD    SG+P  R    A G       PG  G       
Sbjct: 1261 GEPGLPGPEGARGPPGFKGHTGD----SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGP 1316

Query: 269  ---------PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPR 312
                     PG  G   SPG   P G+     +  E G    +PGL G  GPR
Sbjct: 1317 QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG----SPGLPGFLGPR 1365



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 51/182 (28%), Positives = 58/182 (31%), Gaps = 33/182 (18%)

Query: 158  GSVCAADGGGPGA-GAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-LPPPVK 215
            G     D G PG  G+P   G    G  G           P      G  G P  P P  
Sbjct: 1020 GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP----PGDKGSPGSRGLPGFPGPQG 1075

Query: 216  PLSPDGADSGPGTSSPEVRPGSGSENGDGE-----------------SFSGSPLARASKE 258
            P   DGA   PG   P  +PG  S    G+                    G P  +  K 
Sbjct: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 1135

Query: 259  AGGSCPGSAGPGGG-------GEEDSPGSASPLGSESGSEADKEEGEAAPA--PGLGGGS 309
              G  PG  G  G        G    PG A P GS+    AD E G+      PG+ G  
Sbjct: 1136 VPGK-PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194

Query: 310  GP 311
            GP
Sbjct: 1195 GP 1196



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 72/272 (26%), Positives = 88/272 (32%), Gaps = 49/272 (18%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG     G  G  G  G  G+E K            +AG PG P PP +    P G+ 
Sbjct: 1123 GLPGLPGFKGDKGVPGKPGREGTEGKKG----------EAGPPGLPGPPGIA--GPQGSQ 1170

Query: 224  SGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGE---EDSPGS 280
               G      + G     G    F G P       A G    +  PG  G    E  PG 
Sbjct: 1171 GERGADGEVGQKGDQGHPGV-PGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 1229

Query: 281  ASPLG-----SESGSEADKEEGEAAP--------APGLGGGSGPRQRTPLDILTRVFPGH 327
              P G      E G E    +G+  P         PGL G  G R           F GH
Sbjct: 1230 QGPSGLPGIPGEEGKEG--RDGKPGPPGEPGKAGEPGLPGPEGARGPPG-------FKGH 1280

Query: 328  RRGVLELVLQGCGGDVVQAIEQVLNHHRG-----GLAAGLGPAAPPDKAAVGAAAAADDA 382
                     +G  G +    ++ L    G     G     GP  PP K   G+  +  + 
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKN--GSPGSPGEP 1338

Query: 383  WPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
             PS       +    G PGLP  L  GP  PP
Sbjct: 1339 GPSGTPGQKGSKGENGSPGLPGFL--GPRGPP 1368



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 14/155 (9%)

Query: 166 GGPG-AGAPAGTGG-GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
           G PG  GAP   G  G  G  G + + +  D FP      G+ G P P  V    P G  
Sbjct: 578 GPPGRVGAPGLQGERGEKGTRGEKGE-RGLDGFPGKPGDTGQQGRPGPSGVA--GPQGEK 634

Query: 224 SGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASP 283
              G + P   PGS  +    +   G+P  R  + A G  PG+ GP G    D P     
Sbjct: 635 GDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGP-PGARGPIGPEGRDGPPGLQG 693

Query: 284 LGSESGSEADKE-------EGEAAPAPGLGGGSGP 311
           L  + G             +G   P PG+ G  GP
Sbjct: 694 LRGKKGDMGPPGIPGLLGLQGPPGP-PGVPGPPGP 727



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 64/240 (26%), Positives = 77/240 (32%), Gaps = 77/240 (32%)

Query: 204  GRPGSPLPPPVKP----LSPDGADSGPGTSSPEVRPGSGSENG----DGESFSGSPLARA 255
            G+PG P  P  K     + P G    PG + P   PG   + G     GES S   L R 
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGL---PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 1467

Query: 256  SKEAGG--------------------SCPGSAGPGGG-GEEDSPGSASPLGSESGSEADK 294
             +E  G                    S  G  GP G  G++  PG A P+G         
Sbjct: 1468 IQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG--------- 1518

Query: 295  EEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHH 354
            E G     PG GG  GP           + P   RG         G      +       
Sbjct: 1519 EPGR----PGQGGLEGPS--------GPIGPKGERGAK-------GDPGAPGV------- 1552

Query: 355  RGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
              GL   +GP   P +   G    A D  P  +         AG PGLP     GP  PP
Sbjct: 1553 --GLRGEMGPPGIPGQP--GEPGYAKDGLPG-IPGPQGETGPAGHPGLP-----GPPGPP 1602



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 63/252 (25%), Positives = 76/252 (30%), Gaps = 36/252 (14%)

Query: 209 PLPPPVKPLSPDGADSG----------------PGTSSPEVRPGSGSENGDGESFSGSPL 252
           P PPP +P +P     G                 G + P   PG   + G      G+P 
Sbjct: 453 PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIG-AIGPVGAPG 511

Query: 253 ARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPR 312
            +  K   G   G  G G  GE+ S G   P G +       E GE    PGL G  G R
Sbjct: 512 PKGEKGDVGI--GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELG-EPGLPGEVGMR 568

Query: 313 --QRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDK 370
             Q  P        PG    V    LQG  G      E+     +G       P  P D 
Sbjct: 569 GPQGPP------GLPGPPGRVGAPGLQGERG------EKGTRGEKGERGLDGFPGKPGDT 616

Query: 371 AAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQA--GPAAPPHHRPLLAGAMAPGA 428
              G    +  A P         A   G PG     +   G    P  R        PGA
Sbjct: 617 GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676

Query: 429 LGSLSSRSAFSP 440
            G +       P
Sbjct: 677 RGPIGPEGRDGP 688


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 80/296 (27%), Positives = 101/296 (34%), Gaps = 78/296 (26%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PLSPDGA 222
            G PG   P+G  G  GA GA G                  G PG   PP +  P    G 
Sbjct: 993  GFPGLPGPSGEPGKQGAPGASGDR----------------GPPGPVGPPGLTGPAGEPGR 1036

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
            +  PG   P  R G+    GD          R    A G+ PG+ GP G     SPG A 
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGD----------RGETGAVGA-PGAPGPPG-----SPGPAG 1080

Query: 283  PLGS-----ESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQ 337
            P G      E+G++        A A G+ G  GPR                         
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR------------------------- 1115

Query: 338  GCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAA 397
            G  G+  +  E+ L  HRG       P  P      GA+  A  + P         +   
Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1175

Query: 398  GGPGLPAPL----------QAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQP 443
            G  G+P P+          + GPA PP + P   G   PG  G     SAF+ L P
Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG--PPGPPGPGIDMSAFAGLGP 1228



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 82/298 (27%), Positives = 97/298 (32%), Gaps = 67/298 (22%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPL-------S 218
           G PG   P G  G  +GA G +                GRPG P P   +          
Sbjct: 564 GRPGDAGPQGKVG-PSGAPGED----------------GRPGPPGPQGARGQPGVMGFPG 606

Query: 219 PDGADSGPGTSSPEVRPGSGSENG----DGESFSGSPLARASKEAGGSCPGSAGPGGGGE 274
           P GA+  PG +  +  PG+    G    DGE+ +  P   A     G       PG  G 
Sbjct: 607 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAG--PAGERGEQGAPGPSGF 664

Query: 275 EDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLEL 334
           +  PG   P G E G   D+     A APGL G  G R           FPG R      
Sbjct: 665 QGLPGPPGPPG-EGGKPGDQGVPGEAGAPGLVGPRGERG----------FPGERGSPGAQ 713

Query: 335 VLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP-------------DKAAVGAAAAA 379
            LQG  G         L    G  G     GPA PP             ++ A G A   
Sbjct: 714 GLQGPRG---------LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 764

Query: 380 DDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA 437
            D           A    GG GL  P+  GP  P            PG  GS  +R A
Sbjct: 765 GDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGA 820



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 94/320 (29%), Positives = 110/320 (34%), Gaps = 49/320 (15%)

Query: 142  AAANG----IIPPRPAYEVFGSVCAADGGGPGAGAPAGTGG-----GAAGAGGSEAKL-Q 191
            A ANG    + PP PA          + G  G   PAG  G     G  GA G + +  Q
Sbjct: 797  AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 856

Query: 192  KFDL-FPKTLLQAGRPGSPLPPPVK-PLSPDGADSGPG-TSSPEVRPGSGSENGDGESFS 248
            K D   P     +G PG   P  V  P    GA   PG T  P      G    +G    
Sbjct: 857  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 249  GSPLARASKEAGGSCPGSAGPGG-GGEEDSPGSASPLGSESGSEADKEEG-EAAPAP-GL 305
              P   + K+      G +GP G  GE    G A P G +     D   G E  P P GL
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 306  GGGSG----PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG----- 356
             G  G    P QR       R FPG         L G  G+  +      +  RG     
Sbjct: 977  AGQRGIVGLPGQRG-----ERGFPG---------LPGPSGEPGKQGAPGASGDRGPPGPV 1022

Query: 357  GLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAA-----AAAAAAGGPGLPAPL-QAGP 410
            G     GPA  P +     A    D  P R  AA          A G PG P P    GP
Sbjct: 1023 GPPGLTGPAGEPGREGSPGA----DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1078

Query: 411  AAPPHHRPLLAGAMAPGALG 430
            A P   +     A A G +G
Sbjct: 1079 AGPTGKQGDRGEAGAQGPMG 1098



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 75/277 (27%), Positives = 91/277 (32%), Gaps = 53/277 (19%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG   P G  G A   G   A+              G PG      V P+ P G    
Sbjct: 471 GEPGPAGPQGAPGPAGEEGKRGAR--------------GEPGG-----VGPIGPPGERGA 511

Query: 226 PGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAG----PGGGGEEDSPGS 280
           PG      + G +G +   GE     P   A  +     PG  G    PG  G    PG 
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGER---GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 568

Query: 281 ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCG 340
           A P G    S A  E+G   P PG  G  G             FPG +         G  
Sbjct: 569 AGPQGKVGPSGAPGEDGRPGP-PGPQGARGQPG-------VMGFPGPK---------GAN 611

Query: 341 GDVVQAIEQVLNHHRGGLAAGLGPAAPPDK-AAVGAAAAADDAWPSRVDAAAAAAAAAGG 399
           G+  +A E+       GL    G    P K    GAA     A P+       A   +G 
Sbjct: 612 GEPGKAGEK-------GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 400 PGLPAPL-QAGPAAPPHHRPLLAGAMAPGALGSLSSR 435
            GLP P    G    P  + +   A APG +G    R
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 701



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 81/332 (24%), Positives = 95/332 (28%), Gaps = 51/332 (15%)

Query: 166 GGPGAGAPAGTGGGAAG---------AGGSEAKLQKFDLFPKTLLQA------------- 203
           G PG   P G GG  A          AGG++  + +  + P                   
Sbjct: 165 GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQ 224

Query: 204 GRPGSPLPP----PVKPLSPDGADSGPGTSSPEVRPGSGSENG-----DGESFSGSPLAR 254
           G PG P  P    P+ P  P G    PG      +PG   E G         F G+P   
Sbjct: 225 GNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLP 284

Query: 255 ASKEAGG-----SCPGSAG-PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGG 308
             K   G        G AG PG  GE  SPG     G         E G   PA   G  
Sbjct: 285 GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 344

Query: 309 SGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPP 368
               Q  P      V P    G       G  G   +A         G       P  P 
Sbjct: 345 GNDGQPGPAGPPGPVGPAGGPG-----FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399

Query: 369 DKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGA 428
                GA+             +A A   AG PG P P   GP  P        GA  P  
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGP--RGPPGP-------QGATGPLG 450

Query: 429 LGSLSSRSAFSPLQPNASHFGADAGAYPLGAP 460
               +     +  +      G    A P GAP
Sbjct: 451 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 71/266 (26%), Positives = 84/266 (31%), Gaps = 60/266 (22%)

Query: 164 DGGGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PL 217
           + G PG   P G  G     G+ GA G +         P+ L   G PG+  P     P 
Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPGAQGLQG--------PRGL--PGTPGTDGPKGASGPA 737

Query: 218 SPDGADSGPGTSSPEVRPGS----GSENGDGESFSGSPLARASKEAGGSCPGSAGP---- 269
            P GA   PG        G+    G +   G+     P     K+ G    G  GP    
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 797

Query: 270 GGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRR 329
           G  GE+   G   P GS     A  E GE  P PG  G +GP                  
Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGP------------------ 838

Query: 330 GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDA 389
                   G  G      EQ       G A   G A  P     G + A     P+ V  
Sbjct: 839 -------PGADGQPGAKGEQ-------GEAGQKGDAGAP--GPQGPSGAPGPQGPTGVTG 882

Query: 390 AAAAAAAAGGPGLPA-PLQAGPAAPP 414
              A  A G PG    P  AG   PP
Sbjct: 883 PKGARGAQGPPGATGFPGAAGRVGPP 908



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 58/283 (20%)

Query: 164 DGGGPGAGAPAGTG-GGAAGAGGSEAKLQKFDLFPKTLL-QAGRPGSPLPPPVKPLSPDG 221
           DG    AGAP   G  G+ G  GS   +      P+ L  + GR G     P       G
Sbjct: 296 DGAKGEAGAPGVKGESGSPGENGSPGPMG-----PRGLPGERGRTG-----PAGAAGARG 345

Query: 222 ADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGG----GEEDS 277
            D  PG + P   PG     G G  F G+P A+   EAG +  G+ GP G     GE  +
Sbjct: 346 NDGQPGPAGP---PGPVGPAG-GPGFPGAPGAKG--EAGPT--GARGPEGAQGPRGEPGT 397

Query: 278 PGSASPLGSESGSEADKEEGE--AAPAPGLGGGSG-PRQRTPLDILTRVFPGHRRGVLEL 334
           PGS  P G+      D   G   +A APG+ G  G P  R P        PG +     L
Sbjct: 398 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP--------PGPQGATGPL 449

Query: 335 VLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAA 394
             +G  G+              G+A   G   P  K   G A       P+  +    A 
Sbjct: 450 GPKGQTGE-------------PGIAGFKGEQGP--KGEPGPAGPQGAPGPAGEEGKRGAR 494

Query: 395 AAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA 437
              GG         GP  PP  R        PG  G    + A
Sbjct: 495 GEPGG--------VGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 78/265 (29%), Positives = 91/265 (34%), Gaps = 65/265 (24%)

Query: 166 GGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPD 220
           G PGA  P G  G     GAAG  G +    + D+  K     G  G+P           
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKG--DRGDVGEK-----GPEGAP----------- 779

Query: 221 GADSGPGTSSPEVRPGSGSENGD-GESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPG 279
           G D G G + P   PG    NG+ GE     P         GS      PG  GE   PG
Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP--------AGSAGARGAPGERGETGPPG 831

Query: 280 SAS---PLGSESGSEADKEEGEA-----APAPGLGGGSG-PRQRTPLDILTRVFPGHRRG 330
            A    P G++    A  E+GEA     A APG  G SG P  + P  +     P   RG
Sbjct: 832 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV---TGPKGARG 888

Query: 331 VLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAA 390
                 QG  G               G     G   PP   + G         PS  D  
Sbjct: 889 A-----QGPPGAT-------------GFPGAAGRVGPP--GSNGNPGPPGPPGPSGKDGP 928

Query: 391 AAAAAAAGGPGLPA-PLQAGPAAPP 414
             A   +G PG    P   GPA PP
Sbjct: 929 KGARGDSGPPGRAGEPGLQGPAGPP 953



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 83/314 (26%), Positives = 97/314 (30%), Gaps = 87/314 (27%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG   PAG  G     G    K              G PG        P   DG    
Sbjct: 120 GPPGPQGPAGEQGPRGDRGDKGEK--------------GAPG--------PRGRDGEPGT 157

Query: 226 PGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGS----------------CPGSAG- 268
           PG   P   PG     G G +F+        ++AGG+                 PG AG 
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217

Query: 269 ------PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPA--PGLGGGSGPRQRTPLDIL 320
                  G  GE   PG + P+G         + G+   A  PG  G  GP    P    
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP----PGPQG 273

Query: 321 TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP----DKAAVG 374
            R FPG           G  G         +  HRG  GL    G A  P    +  + G
Sbjct: 274 ARGFPG---------TPGLPG---------VKGHRGYPGLDGAKGEAGAPGVKGESGSPG 315

Query: 375 AAAAADDAWPSRV------DAAAAAAAAAGGPGLPAPLQAGPAAP--PHHRPLLAGAMAP 426
              +     P  +         A AA A G  G P P  AGP  P  P   P   G  AP
Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP--AGPPGPVGPAGGPGFPG--AP 371

Query: 427 GALGSLSSRSAFSP 440
           GA G      A  P
Sbjct: 372 GAKGEAGPTGARGP 385


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 80/296 (27%), Positives = 101/296 (34%), Gaps = 78/296 (26%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PLSPDGA 222
            G PG   P+G  G  GA GA G                  G PG   PP +  P    G 
Sbjct: 924  GFPGLPGPSGEPGKQGAPGASGDR----------------GPPGPVGPPGLTGPAGEPGR 967

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
            +  PG   P  R G+    GD          R    A G+ PG+ GP G     SPG A 
Sbjct: 968  EGSPGADGPPGRDGAAGVKGD----------RGETGAVGA-PGAPGPPG-----SPGPAG 1011

Query: 283  PLGS-----ESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQ 337
            P G      E+G++        A A G+ G  GPR                         
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR------------------------- 1046

Query: 338  GCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAA 397
            G  G+  +  E+ L  HRG       P  P      GA+  A  + P         +   
Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1106

Query: 398  GGPGLPAPL----------QAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQP 443
            G  G+P P+          + GPA PP + P   G   PG  G     SAF+ L P
Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG--PPGPPGPGIDMSAFAGLGP 1159



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 82/298 (27%), Positives = 97/298 (32%), Gaps = 67/298 (22%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPL-------S 218
           G PG   P G  G  +GA G +                GRPG P P   +          
Sbjct: 495 GRPGDAGPQGKVG-PSGAPGED----------------GRPGPPGPQGARGQPGVMGFPG 537

Query: 219 PDGADSGPGTSSPEVRPGSGSENG----DGESFSGSPLARASKEAGGSCPGSAGPGGGGE 274
           P GA+  PG +  +  PG+    G    DGE+ +  P   A     G       PG  G 
Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAG--PAGERGEQGAPGPSGF 595

Query: 275 EDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLEL 334
           +  PG   P G E G   D+     A APGL G  G R           FPG R      
Sbjct: 596 QGLPGPPGPPG-EGGKPGDQGVPGEAGAPGLVGPRGERG----------FPGERGSPGAQ 644

Query: 335 VLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP-------------DKAAVGAAAAA 379
            LQG  G         L    G  G     GPA PP             ++ A G A   
Sbjct: 645 GLQGPRG---------LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 695

Query: 380 DDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA 437
            D           A    GG GL  P+  GP  P            PG  GS  +R A
Sbjct: 696 GDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGA 751



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 94/320 (29%), Positives = 110/320 (34%), Gaps = 49/320 (15%)

Query: 142  AAANG----IIPPRPAYEVFGSVCAADGGGPGAGAPAGTGG-----GAAGAGGSEAKL-Q 191
            A ANG    + PP PA          + G  G   PAG  G     G  GA G + +  Q
Sbjct: 728  AGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQ 787

Query: 192  KFDL-FPKTLLQAGRPGSPLPPPVK-PLSPDGADSGPG-TSSPEVRPGSGSENGDGESFS 248
            K D   P     +G PG   P  V  P    GA   PG T  P      G    +G    
Sbjct: 788  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847

Query: 249  GSPLARASKEAGGSCPGSAGPGG-GGEEDSPGSASPLGSESGSEADKEEG-EAAPAP-GL 305
              P   + K+      G +GP G  GE    G A P G +     D   G E  P P GL
Sbjct: 848  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 306  GGGSG----PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG----- 356
             G  G    P QR       R FPG         L G  G+  +      +  RG     
Sbjct: 908  AGQRGIVGLPGQRG-----ERGFPG---------LPGPSGEPGKQGAPGASGDRGPPGPV 953

Query: 357  GLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAA-----AAAAAAGGPGLPAPL-QAGP 410
            G     GPA  P +     A    D  P R  AA          A G PG P P    GP
Sbjct: 954  GPPGLTGPAGEPGREGSPGA----DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1009

Query: 411  AAPPHHRPLLAGAMAPGALG 430
            A P   +     A A G +G
Sbjct: 1010 AGPTGKQGDRGEAGAQGPMG 1029



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 75/277 (27%), Positives = 91/277 (32%), Gaps = 53/277 (19%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG   P G  G A   G   A+              G PG      V P+ P G    
Sbjct: 402 GEPGPAGPQGAPGPAGEEGKRGAR--------------GEPGG-----VGPIGPPGERGA 442

Query: 226 PGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAG----PGGGGEEDSPGS 280
           PG      + G +G +   GE     P   A  +     PG  G    PG  G    PG 
Sbjct: 443 PGNRGFPGQDGLAGPKGAPGER---GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD 499

Query: 281 ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCG 340
           A P G    S A  E+G   P PG  G  G             FPG +         G  
Sbjct: 500 AGPQGKVGPSGAPGEDGRPGP-PGPQGARGQPG-------VMGFPGPK---------GAN 542

Query: 341 GDVVQAIEQVLNHHRGGLAAGLGPAAPPDK-AAVGAAAAADDAWPSRVDAAAAAAAAAGG 399
           G+  +A E+       GL    G    P K    GAA     A P+       A   +G 
Sbjct: 543 GEPGKAGEK-------GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595

Query: 400 PGLPAPL-QAGPAAPPHHRPLLAGAMAPGALGSLSSR 435
            GLP P    G    P  + +   A APG +G    R
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 81/332 (24%), Positives = 95/332 (28%), Gaps = 51/332 (15%)

Query: 166 GGPGAGAPAGTGGGAAG---------AGGSEAKLQKFDLFPKTLLQA------------- 203
           G PG   P G GG  A          AGG++  + +  + P                   
Sbjct: 96  GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQ 155

Query: 204 GRPGSPLPP----PVKPLSPDGADSGPGTSSPEVRPGSGSENG-----DGESFSGSPLAR 254
           G PG P  P    P+ P  P G    PG      +PG   E G         F G+P   
Sbjct: 156 GNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLP 215

Query: 255 ASKEAGG-----SCPGSAG-PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGG 308
             K   G        G AG PG  GE  SPG     G         E G   PA   G  
Sbjct: 216 GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 275

Query: 309 SGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPP 368
               Q  P      V P    G       G  G   +A         G       P  P 
Sbjct: 276 GNDGQPGPAGPPGPVGPAGGPG-----FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 369 DKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGA 428
                GA+             +A A   AG PG P P   GP  P        GA  P  
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGP--RGPPGP-------QGATGPLG 381

Query: 429 LGSLSSRSAFSPLQPNASHFGADAGAYPLGAP 460
               +     +  +      G    A P GAP
Sbjct: 382 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 413



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 71/266 (26%), Positives = 84/266 (31%), Gaps = 60/266 (22%)

Query: 164 DGGGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PL 217
           + G PG   P G  G     G+ GA G +         P+ L   G PG+  P     P 
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQG--------PRGL--PGTPGTDGPKGASGPA 668

Query: 218 SPDGADSGPGTSSPEVRPGS----GSENGDGESFSGSPLARASKEAGGSCPGSAGP---- 269
            P GA   PG        G+    G +   G+     P     K+ G    G  GP    
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA 728

Query: 270 GGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRR 329
           G  GE+   G   P GS     A  E GE  P PG  G +GP                  
Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGP-PGPAGFAGP------------------ 769

Query: 330 GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDA 389
                   G  G      EQ       G A   G A  P     G + A     P+ V  
Sbjct: 770 -------PGADGQPGAKGEQ-------GEAGQKGDAGAP--GPQGPSGAPGPQGPTGVTG 813

Query: 390 AAAAAAAAGGPGLPA-PLQAGPAAPP 414
              A  A G PG    P  AG   PP
Sbjct: 814 PKGARGAQGPPGATGFPGAAGRVGPP 839



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 80/283 (28%), Positives = 100/283 (35%), Gaps = 58/283 (20%)

Query: 164 DGGGPGAGAPAGTG-GGAAGAGGSEAKLQKFDLFPKTLL-QAGRPGSPLPPPVKPLSPDG 221
           DG    AGAP   G  G+ G  GS   +      P+ L  + GR G     P       G
Sbjct: 227 DGAKGEAGAPGVKGESGSPGENGSPGPMG-----PRGLPGERGRTG-----PAGAAGARG 276

Query: 222 ADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGG----GEEDS 277
            D  PG + P   PG     G G  F G+P A+   EAG +  G+ GP G     GE  +
Sbjct: 277 NDGQPGPAGP---PGPVGPAG-GPGFPGAPGAKG--EAGPT--GARGPEGAQGPRGEPGT 328

Query: 278 PGSASPLGSESGSEADKEEGE--AAPAPGLGGGSG-PRQRTPLDILTRVFPGHRRGVLEL 334
           PGS  P G+      D   G   +A APG+ G  G P  R P        PG +     L
Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP--------PGPQGATGPL 380

Query: 335 VLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAA 394
             +G  G+              G+A   G   P  K   G A       P+  +    A 
Sbjct: 381 GPKGQTGE-------------PGIAGFKGEQGP--KGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 395 AAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA 437
              GG         GP  PP  R        PG  G    + A
Sbjct: 426 GEPGG--------VGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 78/265 (29%), Positives = 91/265 (34%), Gaps = 65/265 (24%)

Query: 166 GGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPD 220
           G PGA  P G  G     GAAG  G +    + D+  K     G  G+P           
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKG--DRGDVGEK-----GPEGAP----------- 710

Query: 221 GADSGPGTSSPEVRPGSGSENGD-GESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPG 279
           G D G G + P   PG    NG+ GE     P         GS      PG  GE   PG
Sbjct: 711 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP--------AGSAGARGAPGERGETGPPG 762

Query: 280 SAS---PLGSESGSEADKEEGEA-----APAPGLGGGSG-PRQRTPLDILTRVFPGHRRG 330
            A    P G++    A  E+GEA     A APG  G SG P  + P  +     P   RG
Sbjct: 763 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV---TGPKGARG 819

Query: 331 VLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAA 390
                 QG  G               G     G   PP   + G         PS  D  
Sbjct: 820 A-----QGPPGAT-------------GFPGAAGRVGPP--GSNGNPGPPGPPGPSGKDGP 859

Query: 391 AAAAAAAGGPGLPA-PLQAGPAAPP 414
             A   +G PG    P   GPA PP
Sbjct: 860 KGARGDSGPPGRAGEPGLQGPAGPP 884



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 83/314 (26%), Positives = 97/314 (30%), Gaps = 87/314 (27%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG   PAG  G     G    K              G PG        P   DG    
Sbjct: 51  GPPGPQGPAGEQGPRGDRGDKGEK--------------GAPG--------PRGRDGEPGT 88

Query: 226 PGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGS----------------CPGSAG- 268
           PG   P   PG     G G +F+        ++AGG+                 PG AG 
Sbjct: 89  PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148

Query: 269 ------PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPA--PGLGGGSGPRQRTPLDIL 320
                  G  GE   PG + P+G         + G+   A  PG  G  GP    P    
Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP----PGPQG 204

Query: 321 TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP----DKAAVG 374
            R FPG           G  G         +  HRG  GL    G A  P    +  + G
Sbjct: 205 ARGFPG---------TPGLPG---------VKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 375 AAAAADDAWPSRV------DAAAAAAAAAGGPGLPAPLQAGPAAP--PHHRPLLAGAMAP 426
              +     P  +         A AA A G  G P P  AGP  P  P   P   G  AP
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP--AGPPGPVGPAGGPGFPG--AP 302

Query: 427 GALGSLSSRSAFSP 440
           GA G      A  P
Sbjct: 303 GAKGEAGPTGARGP 316


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 82/310 (26%), Positives = 111/310 (35%), Gaps = 65/310 (20%)

Query: 158 GSVCAAD-----GGGPGAGAP-AGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLP 211
           GS  AAD       G GA +P A   G  A A   EA     +       +A  PGSP  
Sbjct: 62  GSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPTA 121

Query: 212 PPVK----------PLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGG 261
              +          P + DGA   P   +P+ +    S     +  SG    +  KEAG 
Sbjct: 122 AEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFK-LSGFSFKKNKKEAGE 180

Query: 262 SCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILT 321
                A    GG++++ G A+   +E+G+ +    GE A APG    +G           
Sbjct: 181 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAAS----GEQAAAPGEEAAAGEEG-------- 228

Query: 322 RVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADD 381
                             GGD  +A  Q          A + P  PP   A     AA++
Sbjct: 229 ----------------AAGGDPQEAKPQ---------EAAVAPEKPP---ASDETKAAEE 260

Query: 382 AWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPH------HRPLLAGAMAPGALGSLSSR 435
             PS+V+   A  A A      AP  AGP APP         P  A A +  A  S  ++
Sbjct: 261 --PSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEEPAAAAASSACAAPSQEAQ 318

Query: 436 SAFSPLQPNA 445
              SP  P A
Sbjct: 319 PECSPEAPPA 328



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 27/89 (30%), Positives = 36/89 (40%)

Query: 359 AAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRP 418
           A G  PAA  ++ A   + AA  +   + + AAAAA  AG   +     A   A     P
Sbjct: 60  ANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSP 119

Query: 419 LLAGAMAPGALGSLSSRSAFSPLQPNASH 447
             A   A  A  S SS  A     P+ S+
Sbjct: 120 TAAEGEAASAASSTSSPKAEDGATPSPSN 148



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 36/147 (24%), Positives = 52/147 (35%), Gaps = 35/147 (23%)

Query: 254 RASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQ 313
           R  + A  S P  A     G     G ASP  +ESG++ + +   +APA           
Sbjct: 18  RPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKE------- 70

Query: 314 RTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP---AAPPDK 370
                              E    G G     A E      +G  AA   P   A+P +K
Sbjct: 71  -------------------EPAAAGSGAASPSAAE------KGEPAAAAAPEAGASPVEK 105

Query: 371 AAVGAAAAADDAWPSRVDAAAAAAAAA 397
            A     AA+   P+  +  AA+AA++
Sbjct: 106 EAPAEGEAAEPGSPTAAEGEAASAASS 132



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 241 NGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAA 300
           NGD    +    A+   +A GS P +       +++ P +A   G+ S S A+K E  AA
Sbjct: 42  NGDASPAAAESGAKEELQANGSAPAA-------DKEEPAAAGS-GAASPSAAEKGEPAAA 93

Query: 301 PAPGLG 306
            AP  G
Sbjct: 94  AAPEAG 99



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 366 APPDKAAVGAAAAADDAWPSRVDAAAAAAAAA--GGPGLPAPLQAGPAAPPHHRPLLAGA 423
           A  +  A G+A AAD   P+   + AA+ +AA  G P   A  +AG +      P    A
Sbjct: 54  AKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA 113

Query: 424 MAPGALGSLSSRSAFSPLQPNASHFGADAGAYP 456
             PG+  +    +A +    + S   A+ GA P
Sbjct: 114 AEPGSPTAAEGEAASA--ASSTSSPKAEDGATP 144


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 102/346 (29%), Positives = 124/346 (35%), Gaps = 66/346 (19%)

Query: 132  LYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQ 191
            L G      +A  +G   PR    +FG     D G  G   P G  G     G    K +
Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQ--KGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1223

Query: 192  KFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGS-GSENGDGESFSGS 250
              D+ P      G PG P   P  P  P+GAD       P+  PGS GS  G GE   G 
Sbjct: 1224 NGDVGPM-----GPPGPP--GPRGPQGPNGADG------PQGPPGSVGSVGGVGEK--GE 1268

Query: 251  PLARASKEAGG-SCPGSAGPGGG-------GEEDSPGSASPLGSESGSEADKEEGEAAPA 302
            P      EAG    PG AG GG        GE   PG+A P G++     D  +G   P 
Sbjct: 1269 P-----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 303  PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGL 362
             G  G  GP             PG      +    G GGD  +  +        G +   
Sbjct: 1324 -GFPGDPGP-------------PGEPGPAGQ---DGVGGDKGEDGDPG-QPGPPGPSGEA 1365

Query: 363  GPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPPHHRPLLA 421
            GP  PP K     AA A+     +   A   A A G PG   P+   GPA  P    L  
Sbjct: 1366 GPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1423

Query: 422  GAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLR 467
                PG +G            P A+  G D    P+G P GL  L+
Sbjct: 1424 ---IPGPVGEQG--------LPGAA--GQDGPPGPMGPP-GLPGLK 1455



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 91/328 (27%), Positives = 108/328 (32%), Gaps = 71/328 (21%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRP 206
            PP P  E      A   G  G   P G  G  G AG  G          FP    + G P
Sbjct: 1001 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------FPG---ERGLP 1047

Query: 207  GSPLPPPVK----PLSPDGADSGPG------TSSPEVRPG----------SGSENGDGES 246
            G+   P +K    P  P G    PG      T+ P   PG          +G +   GE 
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1107

Query: 247  FSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADK-EEGEAAP---- 301
                P  R   +     PG AGP G   ED          + GS+ DK E G   P    
Sbjct: 1108 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ 1167

Query: 302  ----APGLGGGS---GPRQRTPL-----DILTRVFPGHRRGVLELVLQGCGGDVVQAIEQ 349
                APG+ GG    GPR +  +     D   R FPG       + LQG  G   +  E 
Sbjct: 1168 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGE- 1223

Query: 350  VLNHHRGGLAAGLGPAAPPDKAAVGAAAAAD--DAWPSRVDAAAAAA-----AAAGGPGL 402
                   G    +GP  PP          AD     P  V +            AG PG 
Sbjct: 1224 ------NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1277

Query: 403  PAPLQAGPAAPPHHRPLLAGAMAPGALG 430
            P   +AG   P   R     A  PGA G
Sbjct: 1278 PG--EAGVGGPKGERGEKGEAGPPGAAG 1303



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/148 (31%), Positives = 52/148 (35%), Gaps = 26/148 (17%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG     G  G   G G S AK              G  G P      P  P G    
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAK--------------GESGDP-----GPQGPRGVQGP 581

Query: 226 PG-TSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPL 284
           PG T  P  R   G++ G G    G P A+  +   G  PG   PG  G     G   P 
Sbjct: 582 PGPTGKPGKRGRPGADGGRG--MPGEPGAKGDRGFDG-LPGL--PGDKGHRGERGPQGPP 636

Query: 285 GSESGSEADKEEGEAAPAPGLGGGSGPR 312
           G         E+GE  P  GL G +GPR
Sbjct: 637 GPPGDDGMRGEDGEIGPR-GLPGEAGPR 663



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 79/314 (25%), Positives = 104/314 (33%), Gaps = 65/314 (20%)

Query: 164 DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDL----FPKTLL-QAGRPGSPLPPPVKP 216
           D G  G   P G  G  G  G  G + ++    L     P+ LL   G PG+P  P +  
Sbjct: 623 DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG 682

Query: 217 LSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEED 276
           +  DG     G   P+  PG   + G+       P      +     PG  GP     + 
Sbjct: 683 V--DGPPGPKGNMGPQGEPGPPGQQGNP-----GPQGLPGPQGPIGPPGEKGP-----QG 730

Query: 277 SPGSASPLGSESGSEADKEEGEAAPAPGLG--------GGSGPRQRTPLDILTRV----- 323
            PG A   G++       +EG++     LG        G  GPR     D +  +     
Sbjct: 731 KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 790

Query: 324 ------FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAA 377
                 FPG +    ++ L+G  G+V Q           G     GP  P      G A 
Sbjct: 791 EKGEDGFPGFKG---DMGLKGDRGEVGQI----------GPRGEDGPEGPK-----GRAG 832

Query: 378 AADDAWPSRVDAAAAAAAAAGGPGLPA-PLQAGPAAPPHHRPLLAGAM----APGALGSL 432
              D  PS     A      G PGLP  P + GP       P   GA     A G  G  
Sbjct: 833 PTGDPGPS---GQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKP 888

Query: 433 SSRSAFSPLQPNAS 446
             R    P  P  S
Sbjct: 889 GPRGQRGPTGPRGS 902



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 73/305 (23%), Positives = 89/305 (29%), Gaps = 84/305 (27%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG   P G+ G  G  GA G +               AG+PG     P     P G  
Sbjct: 856  GYPGRQGPKGSTGFPGFPGANGEKGARGV----------AGKPG-----PRGQRGPTGPR 900

Query: 224  SGPGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
               G   P  +PG  G+  GDG                        PG  GE    G   
Sbjct: 901  GSRGARGPTGKPGPKGTSGGDGP-----------------------PGPPGERGPQGPQG 937

Query: 283  PLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGD 342
            P+G                 PG  G  GP  +  L       PGH     E   QG  G 
Sbjct: 938  PVG----------------FPGPKGPPGPPGKDGL-------PGHPGQRGETGFQGKTGP 974

Query: 343  VVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGL 402
                         GG+    GP    +   +G         P        AA   G  G 
Sbjct: 975  ----------PGPGGVVGPQGPTG--ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 1022

Query: 403  PAPL----QAGPAAP---PHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAY 455
            P P     + GPA     P  R L     APG  G    +    P+  +    G+   A 
Sbjct: 1023 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV-GSPGERGSAGTAG 1081

Query: 456  PLGAP 460
            P+G P
Sbjct: 1082 PIGLP 1086



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 45/165 (27%), Positives = 57/165 (34%), Gaps = 17/165 (10%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-LPPPVKPLSPDGA 222
            G PG+    G  G  G  G  G + +     L P T    G  G   +P P  PL P G 
Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGTQGSPGAKGDGGIPGPAGPLGPPGP 1514

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSP--GS 280
               PG   P+   GS    G  +  SG P            PGS GP G   +  P   S
Sbjct: 1515 PGLPGPQGPKGNKGSTGPAGQ-KGDSGLP----------GPPGSPGPPGEVIQPLPILSS 1563

Query: 281  ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFP 325
                    G +AD ++     + G+    G       DI    FP
Sbjct: 1564 KKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFP 1608



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 76/317 (23%), Positives = 87/317 (27%), Gaps = 77/317 (24%)

Query: 169 GAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGT 228
           G G PA T        G  A  +K       +++   PG  +  P  P  P G    PG 
Sbjct: 414 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVE---PGMLVEGPPGPAGPAGIMGPPGL 470

Query: 229 SSPEVRPGSGSENG--------DGESFSGSPLARASKEAGGSCPGSAGP----------- 269
             P   PG   + G          +   G P             GS GP           
Sbjct: 471 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 530

Query: 270 ----------GGGGEEDSPGSASPLGSESGSEADKEEGEAAP--------APGLGGGSGP 311
                     G  G     G   P+G    S A  E G+  P         PG  G  G 
Sbjct: 531 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 590

Query: 312 RQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPD 369
           R R   D   R  PG           G  GD            RG  GL     P  P D
Sbjct: 591 RGRPGAD-GGRGMPGE---------PGAKGD------------RGFDGL-----PGLPGD 623

Query: 370 KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGAL 429
           K   G         P   D         G  GLP   +AGP      R LL     PGA 
Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG--EAGP------RGLLGPRGTPGAP 675

Query: 430 GSLSSRSAFSPLQPNAS 446
           G         P  P  +
Sbjct: 676 GQPGMAGVDGPPGPKGN 692


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 102/346 (29%), Positives = 124/346 (35%), Gaps = 66/346 (19%)

Query: 132  LYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQ 191
            L G      +A  +G   PR    +FG     D G  G   P G  G     G    K +
Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQ--KGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1172

Query: 192  KFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGS-GSENGDGESFSGS 250
              D+ P      G PG P   P  P  P+GAD       P+  PGS GS  G GE   G 
Sbjct: 1173 NGDVGPM-----GPPGPP--GPRGPQGPNGADG------PQGPPGSVGSVGGVGEK--GE 1217

Query: 251  PLARASKEAGG-SCPGSAGPGGG-------GEEDSPGSASPLGSESGSEADKEEGEAAPA 302
            P      EAG    PG AG GG        GE   PG+A P G++     D  +G   P 
Sbjct: 1218 P-----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 303  PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGL 362
             G  G  GP             PG      +    G GGD  +  +        G +   
Sbjct: 1273 -GFPGDPGP-------------PGEPGPAGQ---DGVGGDKGEDGDPG-QPGPPGPSGEA 1314

Query: 363  GPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPPHHRPLLA 421
            GP  PP K     AA A+     +   A   A A G PG   P+   GPA  P    L  
Sbjct: 1315 GPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1372

Query: 422  GAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLR 467
                PG +G            P A+  G D    P+G P GL  L+
Sbjct: 1373 ---IPGPVGEQG--------LPGAA--GQDGPPGPMGPP-GLPGLK 1404



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 91/328 (27%), Positives = 108/328 (32%), Gaps = 71/328 (21%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRP 206
            PP P  E      A   G  G   P G  G  G AG  G          FP    + G P
Sbjct: 950  PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------FPG---ERGLP 996

Query: 207  GSPLPPPVK----PLSPDGADSGPG------TSSPEVRPG----------SGSENGDGES 246
            G+   P +K    P  P G    PG      T+ P   PG          +G +   GE 
Sbjct: 997  GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1056

Query: 247  FSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADK-EEGEAAP---- 301
                P  R   +     PG AGP G   ED          + GS+ DK E G   P    
Sbjct: 1057 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ 1116

Query: 302  ----APGLGGGS---GPRQRTPL-----DILTRVFPGHRRGVLELVLQGCGGDVVQAIEQ 349
                APG+ GG    GPR +  +     D   R FPG       + LQG  G   +  E 
Sbjct: 1117 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGE- 1172

Query: 350  VLNHHRGGLAAGLGPAAPPDKAAVGAAAAAD--DAWPSRVDAAAAAA-----AAAGGPGL 402
                   G    +GP  PP          AD     P  V +            AG PG 
Sbjct: 1173 ------NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1226

Query: 403  PAPLQAGPAAPPHHRPLLAGAMAPGALG 430
            P   +AG   P   R     A  PGA G
Sbjct: 1227 PG--EAGVGGPKGERGEKGEAGPPGAAG 1252



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/148 (31%), Positives = 52/148 (35%), Gaps = 26/148 (17%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG     G  G   G G S AK              G  G P      P  P G    
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAK--------------GESGDP-----GPQGPRGVQGP 530

Query: 226 PG-TSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPL 284
           PG T  P  R   G++ G G    G P A+  +   G  PG   PG  G     G   P 
Sbjct: 531 PGPTGKPGKRGRPGADGGRG--MPGEPGAKGDRGFDG-LPGL--PGDKGHRGERGPQGPP 585

Query: 285 GSESGSEADKEEGEAAPAPGLGGGSGPR 312
           G         E+GE  P  GL G +GPR
Sbjct: 586 GPPGDDGMRGEDGEIGPR-GLPGEAGPR 612



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 79/314 (25%), Positives = 104/314 (33%), Gaps = 65/314 (20%)

Query: 164 DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDL----FPKTLL-QAGRPGSPLPPPVKP 216
           D G  G   P G  G  G  G  G + ++    L     P+ LL   G PG+P  P +  
Sbjct: 572 DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG 631

Query: 217 LSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEED 276
           +  DG     G   P+  PG   + G+       P      +     PG  GP     + 
Sbjct: 632 V--DGPPGPKGNMGPQGEPGPPGQQGNP-----GPQGLPGPQGPIGPPGEKGP-----QG 679

Query: 277 SPGSASPLGSESGSEADKEEGEAAPAPGLG--------GGSGPRQRTPLDILTRV----- 323
            PG A   G++       +EG++     LG        G  GPR     D +  +     
Sbjct: 680 KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 739

Query: 324 ------FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAA 377
                 FPG +    ++ L+G  G+V Q           G     GP  P      G A 
Sbjct: 740 EKGEDGFPGFKG---DMGLKGDRGEVGQI----------GPRGEDGPEGPK-----GRAG 781

Query: 378 AADDAWPSRVDAAAAAAAAAGGPGLPA-PLQAGPAAPPHHRPLLAGAM----APGALGSL 432
              D  PS     A      G PGLP  P + GP       P   GA     A G  G  
Sbjct: 782 PTGDPGPS---GQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKP 837

Query: 433 SSRSAFSPLQPNAS 446
             R    P  P  S
Sbjct: 838 GPRGQRGPTGPRGS 851



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 73/305 (23%), Positives = 89/305 (29%), Gaps = 84/305 (27%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG   P G+ G  G  GA G +               AG+PG     P     P G  
Sbjct: 805  GYPGRQGPKGSTGFPGFPGANGEKGARGV----------AGKPG-----PRGQRGPTGPR 849

Query: 224  SGPGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
               G   P  +PG  G+  GDG                        PG  GE    G   
Sbjct: 850  GSRGARGPTGKPGPKGTSGGDGP-----------------------PGPPGERGPQGPQG 886

Query: 283  PLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGD 342
            P+G                 PG  G  GP  +  L       PGH     E   QG  G 
Sbjct: 887  PVG----------------FPGPKGPPGPPGKDGL-------PGHPGQRGETGFQGKTGP 923

Query: 343  VVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGL 402
                         GG+    GP    +   +G         P        AA   G  G 
Sbjct: 924  ----------PGPGGVVGPQGPTG--ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 971

Query: 403  PAPL----QAGPAAP---PHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAY 455
            P P     + GPA     P  R L     APG  G    +    P+  +    G+   A 
Sbjct: 972  PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV-GSPGERGSAGTAG 1030

Query: 456  PLGAP 460
            P+G P
Sbjct: 1031 PIGLP 1035



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 45/165 (27%), Positives = 57/165 (34%), Gaps = 17/165 (10%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-LPPPVKPLSPDGA 222
            G PG+    G  G  G  G  G + +     L P T    G  G   +P P  PL P G 
Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGTQGSPGAKGDGGIPGPAGPLGPPGP 1463

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSP--GS 280
               PG   P+   GS    G  +  SG P            PGS GP G   +  P   S
Sbjct: 1464 PGLPGPQGPKGNKGSTGPAGQ-KGDSGLP----------GPPGSPGPPGEVIQPLPILSS 1512

Query: 281  ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFP 325
                    G +AD ++     + G+    G       DI    FP
Sbjct: 1513 KKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFP 1557



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 76/317 (23%), Positives = 87/317 (27%), Gaps = 77/317 (24%)

Query: 169 GAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGT 228
           G G PA T        G  A  +K       +++   PG  +  P  P  P G    PG 
Sbjct: 363 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVE---PGMLVEGPPGPAGPAGIMGPPGL 419

Query: 229 SSPEVRPGSGSENG--------DGESFSGSPLARASKEAGGSCPGSAGP----------- 269
             P   PG   + G          +   G P             GS GP           
Sbjct: 420 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479

Query: 270 ----------GGGGEEDSPGSASPLGSESGSEADKEEGEAAP--------APGLGGGSGP 311
                     G  G     G   P+G    S A  E G+  P         PG  G  G 
Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 539

Query: 312 RQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPD 369
           R R   D   R  PG           G  GD            RG  GL     P  P D
Sbjct: 540 RGRPGAD-GGRGMPGE---------PGAKGD------------RGFDGL-----PGLPGD 572

Query: 370 KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGAL 429
           K   G         P   D         G  GLP   +AGP      R LL     PGA 
Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG--EAGP------RGLLGPRGTPGAP 624

Query: 430 GSLSSRSAFSPLQPNAS 446
           G         P  P  +
Sbjct: 625 GQPGMAGVDGPPGPKGN 641


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 102/346 (29%), Positives = 124/346 (35%), Gaps = 66/346 (19%)

Query: 132  LYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQ 191
            L G      +A  +G   PR    +FG     D G  G   P G  G     G    K +
Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQ--KGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211

Query: 192  KFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGS-GSENGDGESFSGS 250
              D+ P      G PG P   P  P  P+GAD       P+  PGS GS  G GE   G 
Sbjct: 1212 NGDVGPM-----GPPGPP--GPRGPQGPNGADG------PQGPPGSVGSVGGVGEK--GE 1256

Query: 251  PLARASKEAGG-SCPGSAGPGGG-------GEEDSPGSASPLGSESGSEADKEEGEAAPA 302
            P      EAG    PG AG GG        GE   PG+A P G++     D  +G   P 
Sbjct: 1257 P-----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 303  PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGL 362
             G  G  GP             PG      +    G GGD  +  +        G +   
Sbjct: 1312 -GFPGDPGP-------------PGEPGPAGQ---DGVGGDKGEDGDPG-QPGPPGPSGEA 1353

Query: 363  GPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPPHHRPLLA 421
            GP  PP K     AA A+     +   A   A A G PG   P+   GPA  P    L  
Sbjct: 1354 GPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1411

Query: 422  GAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLR 467
                PG +G            P A+  G D    P+G P GL  L+
Sbjct: 1412 ---IPGPVGEQG--------LPGAA--GQDGPPGPMGPP-GLPGLK 1443



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 91/328 (27%), Positives = 108/328 (32%), Gaps = 71/328 (21%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRP 206
            PP P  E      A   G  G   P G  G  G AG  G          FP    + G P
Sbjct: 989  PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------FPG---ERGLP 1035

Query: 207  GSPLPPPVK----PLSPDGADSGPG------TSSPEVRPG----------SGSENGDGES 246
            G+   P +K    P  P G    PG      T+ P   PG          +G +   GE 
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1095

Query: 247  FSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADK-EEGEAAP---- 301
                P  R   +     PG AGP G   ED          + GS+ DK E G   P    
Sbjct: 1096 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ 1155

Query: 302  ----APGLGGGS---GPRQRTPL-----DILTRVFPGHRRGVLELVLQGCGGDVVQAIEQ 349
                APG+ GG    GPR +  +     D   R FPG       + LQG  G   +  E 
Sbjct: 1156 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG---PIGLQGLPGPPGEKGE- 1211

Query: 350  VLNHHRGGLAAGLGPAAPPDKAAVGAAAAAD--DAWPSRVDAAAAAA-----AAAGGPGL 402
                   G    +GP  PP          AD     P  V +            AG PG 
Sbjct: 1212 ------NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1265

Query: 403  PAPLQAGPAAPPHHRPLLAGAMAPGALG 430
            P   +AG   P   R     A  PGA G
Sbjct: 1266 PG--EAGVGGPKGERGEKGEAGPPGAAG 1291



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/148 (31%), Positives = 52/148 (35%), Gaps = 26/148 (17%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG     G  G   G G S AK              G  G P      P  P G    
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAK--------------GESGDP-----GPQGPRGVQGP 569

Query: 226 PG-TSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPL 284
           PG T  P  R   G++ G G    G P A+  +   G  PG   PG  G     G   P 
Sbjct: 570 PGPTGKPGKRGRPGADGGRG--MPGEPGAKGDRGFDG-LPGL--PGDKGHRGERGPQGPP 624

Query: 285 GSESGSEADKEEGEAAPAPGLGGGSGPR 312
           G         E+GE  P  GL G +GPR
Sbjct: 625 GPPGDDGMRGEDGEIGPR-GLPGEAGPR 651



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 79/314 (25%), Positives = 104/314 (33%), Gaps = 65/314 (20%)

Query: 164 DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDL----FPKTLL-QAGRPGSPLPPPVKP 216
           D G  G   P G  G  G  G  G + ++    L     P+ LL   G PG+P  P +  
Sbjct: 611 DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG 670

Query: 217 LSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEED 276
           +  DG     G   P+  PG   + G+       P      +     PG  GP     + 
Sbjct: 671 V--DGPPGPKGNMGPQGEPGPPGQQGNP-----GPQGLPGPQGPIGPPGEKGP-----QG 718

Query: 277 SPGSASPLGSESGSEADKEEGEAAPAPGLG--------GGSGPRQRTPLDILTRV----- 323
            PG A   G++       +EG++     LG        G  GPR     D +  +     
Sbjct: 719 KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 778

Query: 324 ------FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAA 377
                 FPG +    ++ L+G  G+V Q           G     GP  P      G A 
Sbjct: 779 EKGEDGFPGFKG---DMGLKGDRGEVGQI----------GPRGEDGPEGPK-----GRAG 820

Query: 378 AADDAWPSRVDAAAAAAAAAGGPGLPA-PLQAGPAAPPHHRPLLAGAM----APGALGSL 432
              D  PS     A      G PGLP  P + GP       P   GA     A G  G  
Sbjct: 821 PTGDPGPS---GQAGEKGKLGVPGLPGYPGRQGPKGSTGF-PGFPGANGEKGARGVAGKP 876

Query: 433 SSRSAFSPLQPNAS 446
             R    P  P  S
Sbjct: 877 GPRGQRGPTGPRGS 890



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 73/305 (23%), Positives = 89/305 (29%), Gaps = 84/305 (27%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG   P G+ G  G  GA G +               AG+PG     P     P G  
Sbjct: 844  GYPGRQGPKGSTGFPGFPGANGEKGARGV----------AGKPG-----PRGQRGPTGPR 888

Query: 224  SGPGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
               G   P  +PG  G+  GDG                        PG  GE    G   
Sbjct: 889  GSRGARGPTGKPGPKGTSGGDGP-----------------------PGPPGERGPQGPQG 925

Query: 283  PLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGD 342
            P+G                 PG  G  GP  +  L       PGH     E   QG  G 
Sbjct: 926  PVG----------------FPGPKGPPGPPGKDGL-------PGHPGQRGETGFQGKTGP 962

Query: 343  VVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGL 402
                         GG+    GP    +   +G         P        AA   G  G 
Sbjct: 963  ----------PGPGGVVGPQGPTG--ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 1010

Query: 403  PAPL----QAGPAAP---PHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAY 455
            P P     + GPA     P  R L     APG  G    +    P+  +    G+   A 
Sbjct: 1011 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV-GSPGERGSAGTAG 1069

Query: 456  PLGAP 460
            P+G P
Sbjct: 1070 PIGLP 1074



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 45/165 (27%), Positives = 57/165 (34%), Gaps = 17/165 (10%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-LPPPVKPLSPDGA 222
            G PG+    G  G  G  G  G + +     L P T    G  G   +P P  PL P G 
Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL-PGTQGSPGAKGDGGIPGPAGPLGPPGP 1502

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSP--GS 280
               PG   P+   GS    G  +  SG P            PGS GP G   +  P   S
Sbjct: 1503 PGLPGPQGPKGNKGSTGPAGQ-KGDSGLP----------GPPGSPGPPGEVIQPLPILSS 1551

Query: 281  ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFP 325
                    G +AD ++     + G+    G       DI    FP
Sbjct: 1552 KKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFP 1596



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 76/317 (23%), Positives = 87/317 (27%), Gaps = 77/317 (24%)

Query: 169 GAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGT 228
           G G PA T        G  A  +K       +++   PG  +  P  P  P G    PG 
Sbjct: 402 GPGVPAETDITETSINGHGAYGEKGQKGEPAVVE---PGMLVEGPPGPAGPAGIMGPPGL 458

Query: 229 SSPEVRPGSGSENG--------DGESFSGSPLARASKEAGGSCPGSAGP----------- 269
             P   PG   + G          +   G P             GS GP           
Sbjct: 459 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 518

Query: 270 ----------GGGGEEDSPGSASPLGSESGSEADKEEGEAAP--------APGLGGGSGP 311
                     G  G     G   P+G    S A  E G+  P         PG  G  G 
Sbjct: 519 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 578

Query: 312 RQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPD 369
           R R   D   R  PG           G  GD            RG  GL     P  P D
Sbjct: 579 RGRPGAD-GGRGMPGE---------PGAKGD------------RGFDGL-----PGLPGD 611

Query: 370 KAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGAL 429
           K   G         P   D         G  GLP   +AGP      R LL     PGA 
Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG--EAGP------RGLLGPRGTPGAP 663

Query: 430 GSLSSRSAFSPLQPNAS 446
           G         P  P  +
Sbjct: 664 GQPGMAGVDGPPGPKGN 680


>gi|126352446 elastin isoform d precursor [Homo sapiens]
          Length = 711

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 115/412 (27%), Positives = 148/412 (35%), Gaps = 59/412 (14%)

Query: 146 GIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFD--LFP------ 197
           G+  P       G      GG P    P G  G   GAG        F   L P      
Sbjct: 40  GVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADA 99

Query: 198 KTLLQAGRPGSPLP--PPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARA 255
               +A + G+ L   P V  L    A S PG   P+  PG+G + G      G P    
Sbjct: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGV-GLP---- 152

Query: 256 SKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRT 315
               GG  PG+  PG G     PG   P G+    +A    G  A  PG+G   GP+   
Sbjct: 153 GVYPGGVLPGARFPGVGV---LPGV--PTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 207

Query: 316 PLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGA 375
           PL      +P     +    L G  G      +    +  GG+A   G A  P    VG 
Sbjct: 208 PLG-----YP-----IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 257

Query: 376 AAAADDAWPSRVDAAAAAAAAAGGPG----LPAPLQAGPAAPPHHRPLLAGAMAPGALGS 431
            AAA         AAAA AAA  G G    LP    AG    P   P + G    G   +
Sbjct: 258 QAAA---------AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308

Query: 432 LSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGL 491
            ++ +A +     A+ +GA AG  P G P G  P  +    A     G+    P +   +
Sbjct: 309 AAAAAAAA----KAAKYGAAAGLVP-GGP-GFGPGVVGVPGAGVPGVGV----PGAGIPV 358

Query: 492 VPTLGF-RPPMDYAFSDLMRDRSAAAAAAVHKEPTYG-GGL--YGPMVNGAP 539
           VP  G     +    S     ++AA AA     P  G GG+  YG    G P
Sbjct: 359 VPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFP 410



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 89/309 (28%), Positives = 105/309 (33%), Gaps = 56/309 (18%)

Query: 165 GGGPGAG-------------APAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAG---RPGS 208
           GG PG G             A  G G  AA A  + AK  +F L P   +  G    PG 
Sbjct: 435 GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGV 494

Query: 209 PLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAG-GSCPGSA 267
            + P V  L+P G    PG     V PG G   G G     +    A+K A       +A
Sbjct: 495 GVAPGVG-LAP-GVGVAPGVG---VAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 549

Query: 268 GPGGGGEEDSPGSASP-LGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPG 326
           G G G      G   P LG  +G       G  A  PG G   G              PG
Sbjct: 550 GLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 606

Query: 327 HRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSR 386
              G+  L   G  G VV                G GPAA    AA  A AAA  A    
Sbjct: 607 VLGGLGALGGVGIPGGVV----------------GAGPAA----AAAAAKAAAKAAQFGL 646

Query: 387 VDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAF--SPLQPN 444
           V AA       GG G+P     G   P         A A  A   +++R  F  SP+ P 
Sbjct: 647 VGAAGLGGLGVGGLGVPGVGGLGGIPP--------AAAAKAAKYGVAARPGFGLSPIFPG 698

Query: 445 ASHFGADAG 453
            +  G   G
Sbjct: 699 GACLGKACG 707



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 104/385 (27%), Positives = 137/385 (35%), Gaps = 82/385 (21%)

Query: 136 AEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDL 195
           A+     AA G++P  P +   G V     G PGAG P   G G  GAG          +
Sbjct: 316 AKAAKYGAAAGLVPGGPGFGP-GVV-----GVPGAGVP---GVGVPGAG--------IPV 358

Query: 196 FPKTLLQAGRPGSPLPPPVKP---------LSPDGADSGPGTSS-PEVRPGSGSENGDGE 245
            P     AG PG+ +P  V P          +  GA  G G    P    G+G   G G 
Sbjct: 359 VPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414

Query: 246 SFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGSASPLGSESG-----SEADKEEGEA 299
              G P        GG  PG  G PG G   ++  +A+   ++ G     + A K   +A
Sbjct: 415 GVGGIPGVAGVPGVGG-VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 473

Query: 300 AP---APGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG 356
           A     PG+G   G            V PG   GV   V    G  V   +         
Sbjct: 474 AQFGLVPGVGVAPG----------VGVAPGV--GVAPGVGLAPGVGVAPGV--------- 512

Query: 357 GLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA-----PLQAGPA 411
           G+A G+G A       V AAA +     ++    AAA   AG PGL        L  G  
Sbjct: 513 GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAG 572

Query: 412 APPHHRPLLAGA------MAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSP 465
            P     L  GA        PGAL +  +    + +       GA  G    G  +G  P
Sbjct: 573 VP----GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 628

Query: 466 LRLAYSAAAAHSRGLAFMAPYSTAG 490
                +AAAA ++  A  A +   G
Sbjct: 629 -----AAAAAAAKAAAKAAQFGLVG 648


>gi|126352322 elastin isoform c precursor [Homo sapiens]
          Length = 692

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 115/412 (27%), Positives = 148/412 (35%), Gaps = 59/412 (14%)

Query: 146 GIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFD--LFP------ 197
           G+  P       G      GG P    P G  G   GAG        F   L P      
Sbjct: 40  GVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADA 99

Query: 198 KTLLQAGRPGSPLP--PPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARA 255
               +A + G+ L   P V  L    A S PG   P+  PG+G + G      G P    
Sbjct: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGV-GLP---- 152

Query: 256 SKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRT 315
               GG  PG+  PG G     PG   P G+    +A    G  A  PG+G   GP+   
Sbjct: 153 GVYPGGVLPGARFPGVGV---LPGV--PTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 207

Query: 316 PLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGA 375
           PL      +P     +    L G  G      +    +  GG+A   G A  P    VG 
Sbjct: 208 PLG-----YP-----IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 257

Query: 376 AAAADDAWPSRVDAAAAAAAAAGGPG----LPAPLQAGPAAPPHHRPLLAGAMAPGALGS 431
            AAA         AAAA AAA  G G    LP    AG    P   P + G    G   +
Sbjct: 258 QAAA---------AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308

Query: 432 LSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGL 491
            ++ +A +     A+ +GA AG  P G P G  P  +    A     G+    P +   +
Sbjct: 309 AAAAAAAA----KAAKYGAAAGLVP-GGP-GFGPGVVGVPGAGVPGVGV----PGAGIPV 358

Query: 492 VPTLGF-RPPMDYAFSDLMRDRSAAAAAAVHKEPTYG-GGL--YGPMVNGAP 539
           VP  G     +    S     ++AA AA     P  G GG+  YG    G P
Sbjct: 359 VPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFP 410



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 85/296 (28%), Positives = 101/296 (34%), Gaps = 43/296 (14%)

Query: 165 GGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAG---RPGSPLPPPVKPLSPDG 221
           GG PG G   G G        + AK  K+ L P   +  G    PG  + P V  L+P G
Sbjct: 429 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG-LAP-G 486

Query: 222 ADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAG-GSCPGSAGPGGGGEEDSPGS 280
               PG     V PG G   G G     +    A+K A       +AG G G      G 
Sbjct: 487 VGVAPGVG---VAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGV 543

Query: 281 ASP-LGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGC 339
             P LG  +G       G  A  PG G   G              PG   G+  L   G 
Sbjct: 544 GVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600

Query: 340 GGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGG 399
            G VV                G GPAA    AA  A AAA  A    V AA       GG
Sbjct: 601 PGGVV----------------GAGPAA----AAAAAKAAAKAAQFGLVGAAGLGGLGVGG 640

Query: 400 PGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAF--SPLQPNASHFGADAG 453
            G+P     G   P         A A  A   +++R  F  SP+ P  +  G   G
Sbjct: 641 LGVPGVGGLGGIPP--------AAAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 688



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 100/377 (26%), Positives = 131/377 (34%), Gaps = 85/377 (22%)

Query: 136 AEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDL 195
           A+     AA G++P  P +   G V     G PGAG P   G G  GAG          +
Sbjct: 316 AKAAKYGAAAGLVPGGPGFGP-GVV-----GVPGAGVP---GVGVPGAG--------IPV 358

Query: 196 FPKTLLQAGRPGSPLPPPVKP---------LSPDGADSGPGTSS-PEVRPGSGSENGDGE 245
            P     AG PG+ +P  V P          +  GA  G G    P    G+G   G G 
Sbjct: 359 VPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414

Query: 246 SFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPG 304
              G P        GG  PG  G PG G   ++  +A+   ++ G           P  G
Sbjct: 415 GVGGIPGVAGVPGVGG-VPGVGGVPGVGISPEAQAAAAAKAAKYG---------LVPGVG 464

Query: 305 LGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP 364
           +  G G            V PG   GV   V    G  V   +         G+A G+G 
Sbjct: 465 VAPGVG------------VAPGV--GVAPGVGLAPGVGVAPGV---------GVAPGVGV 501

Query: 365 AAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA-----PLQAGPAAPPHHRPL 419
           A       V AAA +     ++    AAA   AG PGL        L  G   P     L
Sbjct: 502 APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP----GL 557

Query: 420 LAGA------MAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAA 473
             GA        PGAL +  +    + +       GA  G    G  +G  P     +AA
Sbjct: 558 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP-----AAA 612

Query: 474 AAHSRGLAFMAPYSTAG 490
           AA ++  A  A +   G
Sbjct: 613 AAAAKAAAKAAQFGLVG 629


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 88/309 (28%), Positives = 103/309 (33%), Gaps = 44/309 (14%)

Query: 137 EGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLF 196
           E +A A+  G+ PP  A+       AA        A  G G    G G S A+       
Sbjct: 94  EHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPP 153

Query: 197 PKTLLQAGRPGSPLPPPVKPL--------SPDGADSGPGTSSPEVRPGSGSENGDGESFS 248
              L     P  P PPP  P         S  G  SG G S   V     S      +  
Sbjct: 154 APPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMH 213

Query: 249 GSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGG 308
           G+PL    +   GS    A P        P SA    S SG+ A           G  G 
Sbjct: 214 GAPLGGEQRSGTGSPQHPAPP--------PHSAGMFISASGTYA-----------GPDGS 254

Query: 309 SGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPP 368
            GP     L        GH   +   +  G       A  ++        A   G A   
Sbjct: 255 GGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDA--- 311

Query: 369 DKAAVGAAAAAD----DAWPSRVDAAAAAAAAAGGPG------LPAPLQAGPAAP---PH 415
              AV AAAAA      A    ++ AAAAAAAA GPG       P P    P AP   PH
Sbjct: 312 HYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPPAPAQHPH 371

Query: 416 -HRPLLAGA 423
            H P L GA
Sbjct: 372 QHHPHLPGA 380



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 84/347 (24%), Positives = 113/347 (32%), Gaps = 58/347 (16%)

Query: 170 AGAPAGTGGGAAGAG------GSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
           AG PA +   AA A       G++  +    L P+ + QA   G   P    P  P+   
Sbjct: 60  AGPPAHSQLRAAVAHLRLRDLGADPGVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPA 119

Query: 224 SGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASP 283
           +    ++    PG+GS    G S    P          S P    P        P + SP
Sbjct: 120 AAARAAALVAHPGAGSYPCGGGSSGAQP----------SAPPPPAP------PLPPTPSP 163

Query: 284 LGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRG-VLELVLQGCGGD 342
                        G      G GG SG               GH R  VL   L      
Sbjct: 164 PPPPPPPPPPALSGYTTTNSGGGGSSG--------------KGHSRDFVLRRDLSATAPA 209

Query: 343 VVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGL 402
                  +    R G  +   PA PP  A +  +A+   A P            +GGP L
Sbjct: 210 AAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPD----------GSGGPAL 259

Query: 403 PAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA---------FSPLQPNASHFGADAG 453
              L   P AP  H   L G M  G   + ++ +A         F+P   +A H+GA A 
Sbjct: 260 FPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDA-HYGAVAA 318

Query: 454 AYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRPP 500
           A    A  G   + L  + AAA +   A   P+      P     PP
Sbjct: 319 A-AAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPPPPP 364


>gi|24432032 zinc finger protein 503 [Homo sapiens]
          Length = 646

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 96/366 (26%), Positives = 117/366 (31%), Gaps = 52/366 (14%)

Query: 154 YEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPP 213
           Y   GS     GGG G G   G GGG   +  S  ++      P T     R GSP    
Sbjct: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFT----PRTGSP-SSS 232

Query: 214 VKPLSPDGADSGPGTSSPEVRP-------GSGSENGDGESFSGSPLARASKEAGGSCPGS 266
               SP G  S  G  +PE +        G G +   G S  G P   A      SC G 
Sbjct: 233 ASACSPGGMLSSAG-GAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRI--SCGGG 289

Query: 267 AGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPG 326
                    D       LGS+ G  +           G   GSGP   T   +L      
Sbjct: 290 INVDVNQHPDGGPGGKALGSDCGGSS-----------GSSSGSGPSAPTSSSVLGS---- 334

Query: 327 HRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSR 386
              G++  V     G  V  +      + G LA G     PP     G A   D   P  
Sbjct: 335 ---GLVAPVSPYKPGQTVFPLPPAGMTYPGSLA-GAYAGYPPQFLPHGVAL--DPTKPGS 388

Query: 387 VDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNAS 446
           +  A  AAAAAG  G   P  + P         LAGA  P  + +   R  +      AS
Sbjct: 389 LVGAQLAAAAAGSLGCSKPAGSSP---------LAGASPPSVMTASLCRDPYCLSYHCAS 439

Query: 447 HFGADAGAY------PLGAPLGL-SPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRP 499
           H    A A       P  A   L S   L Y     H    +  A  +     P+L   P
Sbjct: 440 HLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHP 499

Query: 500 PMDYAF 505
              Y F
Sbjct: 500 LYPYGF 505



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 104/392 (26%), Positives = 131/392 (33%), Gaps = 69/392 (17%)

Query: 174 AGTGGGAAGAGGSEAKLQKFDLFPKTLLQAG-RPGSPLPPPVKPLSPDGADSGPGTSSPE 232
           A  GGGA GAGG  A  +     P  L   G    S   P  KP S      G G     
Sbjct: 138 ASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGG-- 195

Query: 233 VRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGS--ASPLGSESGS 290
              G G   G G S   S     S       P +  P       SPG   +S  G+  G 
Sbjct: 196 ---GGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGK 252

Query: 291 EADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQV 350
           +  K+        G GG S     T L         H R         CGG +   + Q 
Sbjct: 253 DDKKDTDVGGGGKGTGGASAEGGPTGL--------AHGR-------ISCGGGINVDVNQH 297

Query: 351 LNHHRGGLA------------AGLGPAAPPDKAAVGAAAAA--------DDAWP----SR 386
            +   GG A            +G GP+AP   + +G+   A           +P      
Sbjct: 298 PDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGM 357

Query: 387 VDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGA-MAPGALGSL--SSRSAFSPLQP 443
               + A A AG P  P  L  G A  P     L GA +A  A GSL  S  +  SPL  
Sbjct: 358 TYPGSLAGAYAGYP--PQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPL-- 413

Query: 444 NASHFGADAGAYP---LGAPLGLSPLRLAYSAAA--AHSRGLAFMAPYSTAGLVPTLGFR 498
                   AGA P   + A L   P  L+Y  A+  A +   +    +  A     L   
Sbjct: 414 --------AGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSG 465

Query: 499 PPMDYAFSDL--MRDRSAAAAAAVHKEPTYGG 528
            P+ Y    L  +     AAAAA    P+  G
Sbjct: 466 YPLVYPTHPLHGVHSSLTAAAAAGATPPSLAG 497


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 82/296 (27%), Positives = 111/296 (37%), Gaps = 43/296 (14%)

Query: 144 ANGIIP-PRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEA--KLQKFDLFPKTL 200
           A+G  P P+P       +   +G  P    P      A G+G + A  K++  D    +L
Sbjct: 209 ADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAA-ALGSGSAAAVPKIESPDSSSSSL 267

Query: 201 LQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGE----SFSGSPLARAS 256
                P   LP   +PLS DGADS P   +P   P   S+    +    S  GSP + A+
Sbjct: 268 SSGSSPPGSLPS-ARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAA 326

Query: 257 KEAGGSCPGSAGPGGGGEED-------SPGS----ASPLGSESGSEADKEEGEAAPAPGL 305
           + + G    +A     G          SPG     +SP    S + +    G  A A G 
Sbjct: 327 ELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGG 386

Query: 306 GGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGD-------------VVQAIEQVLN 352
            GG+G      L  ++    G R G L+    G GG              V  +    L+
Sbjct: 387 AGGAG-TYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLS 445

Query: 353 HHRGGLAAGLGPAAPPDKAAVGAA-------AAADDAWPSRVDAAAAAAAAAGGPG 401
           H  GG   G G  A    AA            A  D     + +AAAAAAAAG PG
Sbjct: 446 HGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDL--GHLASAAAAAAAAGYPG 499



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 79/338 (23%), Positives = 116/338 (34%), Gaps = 72/338 (21%)

Query: 8   PSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPRT 67
           P  P AA  + + A  P + S  S +++ ++ +S P    G L    PL L  A+  P  
Sbjct: 239 PLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPP----GSLPSARPLSLDGADSAPPP 294

Query: 68  PKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEAR 127
           P  +    H                              +  +    +   +   ++ A 
Sbjct: 295 PAPSAPPPH----------------------------HSQGFSVDNIMTSLRGSPQSAAA 326

Query: 128 ELQLLYGTAEGLALAAANGIIPPRP--AYE-----VFGSVCA---ADGGGPGAGAPAGTG 177
           EL    G     A ++  GI PP    AY      ++ S C+   + G   G G  AG  
Sbjct: 327 ELSS--GLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAA 384

Query: 178 GGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGS 237
           GGA GAG     LQ   L+      AG  G  L          GA  G G          
Sbjct: 385 GGAGGAGTYHCNLQAMSLY-----AAGERGGHL---------QGAPGGAG---------- 420

Query: 238 GSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASPLGSESG---SEADK 294
           GS   D       P   +S  +  S  G  G GGGG+E     A+  G  +    ++A  
Sbjct: 421 GSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGG 480

Query: 295 EEGEAAPAPGLGGGSG-PRQRTPLDILTRVFPGHRRGV 331
           + G  A A      +G P Q+     +  +F   R G+
Sbjct: 481 DLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGL 518



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 79/329 (24%), Positives = 111/329 (33%), Gaps = 36/329 (10%)

Query: 206 PGSPLPPPVKPLSPDGADSGPGTSSPEVR-PGSGSENGDGESFSGSPLARASKEAGGSC- 263
           P    PPP  P   DG  + PG   P VR     +ENG   S    PL+ A+    GS  
Sbjct: 196 PPGRQPPPAPPEQADG--NAPGPQPPPVRIQDIKTENGTCPS-PPQPLSPAAALGSGSAA 252

Query: 264 --PGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILT 321
             P    P       S GS+ P    S      +  ++AP P       P    P     
Sbjct: 253 AVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPP-------PAPSAPP---- 301

Query: 322 RVFPGHRRGV-LELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAAD 380
              P H +G  ++ ++    G    A  ++ +      AA       P  A    +    
Sbjct: 302 ---PHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQS 358

Query: 381 DAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAM-APGALGSLSSRSAFS 439
             + S     ++A ++ GG G          A  +H  L A ++ A G  G         
Sbjct: 359 SLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERG--------G 410

Query: 440 PLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLG--- 496
            LQ      G  A   PL     L P+  + S++ +H  G         AG  P      
Sbjct: 411 HLQGAPGGAGGSAVDDPL-PDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGR 469

Query: 497 -FRPPMDYAFSDLMRDRSAAAAAAVHKEP 524
                ++ A  DL    SAAAAAA    P
Sbjct: 470 LTSWYLNQAGGDLGHLASAAAAAAAAGYP 498


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 86/302 (28%), Positives = 105/302 (34%), Gaps = 40/302 (13%)

Query: 162 AADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDG 221
           A   G PGA  P G  G    AG +     + ++        G PG  L  PV P    G
Sbjct: 252 AGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV--------GLPG--LSGPVGPPGNPG 301

Query: 222 ADSGPGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGG----GEED 276
           A+   G       PG +G+    G      P+  A         G  GP G     G + 
Sbjct: 302 ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361

Query: 277 SPGSASPLG--SESGSEADK----EEGEAAP--APGLGGGSGPRQRTPLDILTRVF--PG 326
            PGSA P G    SG E  +    E G A P   PGL G  G R     D    V   PG
Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 327 HRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPDKAAVGAAAAADDAWP 384
            R       ++G  GD  +  E  L   RG  G    +GPA    +  VG      D  P
Sbjct: 422 SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG--KEGPVGLPGI--DGRP 477

Query: 385 SRVDAAAAAAAAAGGPGLPAPLQAGPAAPP------HHRPLLAGAMAPGALGSLSSRSAF 438
             +   A A    G  G P P   GP   P       H  L     APG  G+  ++   
Sbjct: 478 GPI-GPAGARGEPGNIGFPGP--KGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534

Query: 439 SP 440
            P
Sbjct: 535 GP 536



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 83/304 (27%), Positives = 98/304 (32%), Gaps = 46/304 (15%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP--LPPPVK--PLSP 219
           G  GA  PAG  G  G AG  G           P  +   G PGSP  + P  K  P+  
Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGE----------PGLMGPRGLPGSPGNIGPAGKEGPVGL 470

Query: 220 DGADSGPGTSSPEVRPGSGSENG--DGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDS 277
            G D  PG   P    G     G    +  +G P     K   G       PG  G   +
Sbjct: 471 PGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGA 530

Query: 278 PGSASPLGSESGSEADKEEGEAAPA--PGLGGGSGPRQRTPLDILTRVFPGHRRGVLELV 335
            G   P G + G     E+G   P    GL G SGP             PG R    E  
Sbjct: 531 QGPPGPQGVQGGK---GEQGPPGPPGFQGLPGPSGPAGEVGK-------PGERGLHGEFG 580

Query: 336 LQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP-------DKAAVGAAAAADDAWPSR 386
           L G  G   +      +   G  G     GP+ PP       +   VGA   A  + PS 
Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640

Query: 387 VDAAAAAAAAAGG------PGLPAPLQAGPAAPPHHRPLLAGAMAP-GALGSLSSRSAFS 439
           +     AA   GG      PGL   +           P   GA  P GA G      A  
Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAG 700

Query: 440 PLQP 443
           P  P
Sbjct: 701 PAGP 704



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 72/251 (28%), Positives = 84/251 (33%), Gaps = 48/251 (19%)

Query: 162 AADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PLSPD 220
           A + G PG   PAG  G A   G +               + G PG P  P  +  + P 
Sbjct: 117 AGEPGEPGQTGPAGARGPAGPPGKAG--------------EDGHPGKPGRPGERGVVGPQ 162

Query: 221 GADSGPGTSSPEVRPGSGSENG-DGESFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSP 278
           GA   PGT       G    NG DG    G P A   K   G+ PG  G PG  G    P
Sbjct: 163 GARGFPGTPGLPGFKGIRGHNGLDG--LKGQPGAPGVKGEPGA-PGENGTPGQTGARGLP 219

Query: 279 GSASPLGSESGSEADKEEGEAAPAPGLG--GGSGPRQRTPLDILTRVFPGHRRGVLELVL 336
           G    +G+   + A   +G   P    G  G +GP            FPG      E+  
Sbjct: 220 GERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPG----------FPGAPGPKGEIGA 269

Query: 337 QGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAA 394
            G  G    A        RG  GL    GP  PP          A          AA   
Sbjct: 270 VGNAGPAGPA------GPRGEVGLPGLSGPVGPPGNPGANGLTGA--------KGAAGLP 315

Query: 395 AAAGGPGLPAP 405
             AG PGLP P
Sbjct: 316 GVAGAPGLPGP 326



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 77/291 (26%), Positives = 97/291 (33%), Gaps = 63/291 (21%)

Query: 166 GGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQ--AGRPGSPLPP------ 212
           GG G   P G  G     G +G  G   K  +  L  +  L   AG  G   PP      
Sbjct: 541 GGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAA 600

Query: 213 -PVKPLSPDGADSGPGTSSPEVRPG----------SGSENGDGE-SFSGSPLARASKEAG 260
            P  P+   G    PG    +  PG          SG     GE   +G P  +  K   
Sbjct: 601 GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEP 660

Query: 261 GSCPGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDIL 320
           G       PG  G   +PG+   +G+   + A  + GEA  A G  G +GPR        
Sbjct: 661 GLRGEIGNPGRDGARGAPGA---VGAPGPAGATGDRGEAG-AAGPAGPAGPRGS------ 710

Query: 321 TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG-----------------GLAAGLG 363
               PG R  V      G  G    A +      RG                 G A   G
Sbjct: 711 ----PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAG 766

Query: 364 PAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
           P  PP     G A +  D  P  +     AA   G PG P+ + +GP  PP
Sbjct: 767 PNGPP-----GPAGSRGDGGPPGMTGFPGAAGRTGPPG-PSGI-SGPPGPP 810



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 78/298 (26%), Positives = 90/298 (30%), Gaps = 53/298 (17%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G  G   P G  G A  AG   AK ++    PK     G  G      V P  P GA   
Sbjct: 715 GEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPK-----GENGV-----VGPTGPVGAAGP 764

Query: 226 PGTSSPEVRPGSGSENGDG--ESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASP 283
            G + P   PG     GDG     +G P A       G    S  PG  G     G   P
Sbjct: 765 AGPNGP---PGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGP 821

Query: 284 LGSESGSEADKEEGEAAPAPGLGGGSGPRQRT----------PLDILTRV----FPGHRR 329
            G +       E G   P PG  G  GP              P  +L        PG R 
Sbjct: 822 RGDQGPVGRTGEVGAVGP-PGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRG 880

Query: 330 GVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDA 389
              E  L G  G V             G    LG A PP     GA           V+ 
Sbjct: 881 ---ERGLPGVAGAV-------------GEPGPLGIAGPP-----GARGPPGAVGSPGVNG 919

Query: 390 AAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASH 447
           A   A   G PG   P   G    P H+         G +G+  +     P+ P   H
Sbjct: 920 APGEAGRDGNPGNDGP--PGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKH 975



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 75/284 (26%), Positives = 95/284 (33%), Gaps = 58/284 (20%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G  GA  P G  G  G +G  G+                AG PG+P P  +  L   G  
Sbjct: 832  GEVGAVGPPGFAGEKGPSGEAGT----------------AGPPGTPGPQGL--LGAPGIL 873

Query: 224  SGPGTSSPEVRPGSGSENGDGE--SFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSA 281
              PG+      PG     G+      +G P AR    A GS   +  PG  G + +PG+ 
Sbjct: 874  GLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGND 933

Query: 282  SPLGSESGSEADKEEG--------EAAPAPGLGGGSGPRQR----------TPLDILTRV 323
             P G +       E G         AA APG  G  GP  +           P+     V
Sbjct: 934  GPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993

Query: 324  FPGHRRGVLELVLQGCGGDVVQAIEQ------VLNHHRG-----GLAAGLG-PAAPPDKA 371
             P    G      QG  GD  +  E+       L  H G     G+A   G   AP    
Sbjct: 994  GPRGPSGP-----QGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVG 1048

Query: 372  AVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPP 414
              G    A  + P+  D         G  G+  P    GPA PP
Sbjct: 1049 PAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPP 1092



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 87/326 (26%), Positives = 108/326 (33%), Gaps = 72/326 (22%)

Query: 204 GRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSE-----NGDGESFSGSPLARASKE 258
           G  G P PP       DG    PG   P   PG G       +G G      P+      
Sbjct: 42  GERGPPGPPGRD--GEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR 99

Query: 259 AGGSCPGSAGPGG----GGEEDSPGSASPLGS--------ESGSEADK-------EEGEA 299
                 G+ GP G     GE   PG   P G+        ++G +          E G  
Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVV 159

Query: 300 AP--------APGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVL 351
            P         PGL G  G R    LD L +  PG      E    G  G   Q   + L
Sbjct: 160 GPQGARGFPGTPGLPGFKGIRGHNGLDGL-KGQPGAPGVKGEPGAPGENGTPGQTGARGL 218

Query: 352 NHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL----- 406
              RG + A  GPA        GA  +     P        +A   G PG P P      
Sbjct: 219 PGERGRVGAP-GPA--------GARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGA 269

Query: 407 --QAGPAAPPHHR-----PLLAGAMA----PGALGSLSSRSAFSPLQPNASHFGADAGAY 455
              AGPA P   R     P L+G +     PGA G   ++         A+     AGA 
Sbjct: 270 VGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK--------GAAGLPGVAGAP 321

Query: 456 PLGAPLGL-SPLRLAYSAAAAHSRGL 480
            L  P G+  P+    +A A  +RGL
Sbjct: 322 GLPGPRGIPGPVG---AAGATGARGL 344



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 24/86 (27%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 164  DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDG 221
            D G PG+  PAG  G  G +G  G + +              G PG+  P  ++   P G
Sbjct: 1040 DQGAPGSVGPAGPRGPAGPSGPAGKDGR-------------TGHPGTVGPAGIR--GPQG 1084

Query: 222  ADSGPGTSSPEVRPGSGSENGDGESF 247
                 G   P   PG    +G G  F
Sbjct: 1085 HQGPAGPPGPPGPPGPPGVSGGGYDF 1110


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 82/311 (26%), Positives = 99/311 (31%), Gaps = 44/311 (14%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
           G PG   P G  G     G  +  L             G+PG   PP    +   G    
Sbjct: 83  GKPGPRGPPGPPGFPGKPGMGKPGLH------------GQPGPAGPPGFSRMGKAGPPGL 130

Query: 226 PGTSSPEVRPGSGSENG--DGESFSGSPLARASKEAGG-SCPGSAG-------PGGGGEE 275
           PG   P  +PG   E G    +   G P         G + PG  G       PG  GE 
Sbjct: 131 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP 190

Query: 276 DSPGSASPLGSESGSEADKEEGEAA--PAPGLGGGSGPRQRT-PLDILTRVFPGHRRGVL 332
              G   P G + G + D   G+     APG GG  GP     P  +      G      
Sbjct: 191 GPQGEPGPPG-DRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDG------ 243

Query: 333 ELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAA 392
              L G  GD  ++    +   RG   A +GP  PP    VG   AA    P     A  
Sbjct: 244 ---LPGAPGDKGESGPPGVPGPRGEPGA-VGPKGPPGVDGVGVPGAAGLPGPQGPSGAKG 299

Query: 393 AAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADA 452
                G PGL  P   G    P  +     A  PG LG           +P       + 
Sbjct: 300 EPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRG--------EPGEDGEPGEQ 351

Query: 453 GAYPLGAPLGL 463
           G   LG P GL
Sbjct: 352 GPQGLGGPPGL 362



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 69/255 (27%), Positives = 84/255 (32%), Gaps = 27/255 (10%)

Query: 166 GGPGAGAPAG----TGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDG 221
           G PG   P G    TG G  G  G +       + P  L   G PG    P  +   P G
Sbjct: 299 GEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGV-PGLLGDRGEPGEDGEPGEQ--GPQG 355

Query: 222 ADSGPGTSSPEVRPGS-GSENGDGESFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPG 279
               PG       PG  G     GE+  G P             G AG PG  GE   PG
Sbjct: 356 LGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPG 415

Query: 280 SASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGC 339
           +  P G  +G + +         PG+ G  G +     D+     PG R       LQG 
Sbjct: 416 AHGPPGP-TGPKGEPGFTGRPGGPGVAGALGQKG----DLGLPGQPGLRGPSGIPGLQGP 470

Query: 340 GGDV-VQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAG 398
            G +  Q +         GL    G   PP +   G    A    P  V  +       G
Sbjct: 471 AGPIGPQGLP--------GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG 522

Query: 399 GPGLPAPLQAGPAAP 413
            PG P P    P AP
Sbjct: 523 PPGPPGP----PGAP 533



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 32/114 (28%), Positives = 39/114 (34%), Gaps = 15/114 (13%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP------LPPPVKPL 217
           G PG   P+G  G  G AG  G +         P    + G PG P       P    P 
Sbjct: 454 GQPGLRGPSGIPGLQGPAGPIGPQG-------LPGLKGEPGLPGPPGEGRAGEPGTAGPT 506

Query: 218 SPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGG 271
            P G    PG + P   PG     G   +F  + +A      GG      G GG
Sbjct: 507 GPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGG 560


>gi|126352608 elastin isoform e precursor [Homo sapiens]
          Length = 705

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 119/426 (27%), Positives = 154/426 (36%), Gaps = 56/426 (13%)

Query: 138 GLALAAANGIIPPRPAYEVFGSVCAADGGG---PGAGAPAGTGGGAAGAGGSEAKLQKFD 194
           G+ L   + + P RP   V G++     GG   PGAG  A  GGGA G GG   K     
Sbjct: 12  GVLLLLLSILHPSRPG-GVPGAIPGGVPGGVFYPGAGLGA-LGGGALGPGGKPLKPVPGG 69

Query: 195 LFPKTLLQAGRPGSPLPPPVKPLSPDG-ADSGPGTSSPEVRPGSGSENGDGESFSGSPLA 253
           L    L  AG    P       L P G AD+     + +   G G   G G     +   
Sbjct: 70  LAGAGL-GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128

Query: 254 RASKEAG---GSCPGSAGPGGGGEEDSPGS---------ASPLGSESGSEADKEEGEAAP 301
                AG   G  PG   PG       PG+           P G+    +A    G  A 
Sbjct: 129 VPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAG 188

Query: 302 APGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAG 361
            PG+G   GP+   PL      +P     +    L G  G      +    +  GG+A  
Sbjct: 189 IPGVGPFGGPQPGVPLG-----YP-----IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGA 238

Query: 362 LGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPG----LPAPLQAGPAAPPHHR 417
            G A  P    VG  AAA         AAAA AAA  G G    LP    AG    P   
Sbjct: 239 AGKAGYPTGTGVGPQAAA---------AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI 289

Query: 418 PLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHS 477
           P + G    G   + ++ +A +     A+ +GA AG  P G P G  P  +    A    
Sbjct: 290 PGIGGIAGVGTPAAAAAAAAAA----KAAKYGAAAGLVP-GGP-GFGPGVVGVPGAGVPG 343

Query: 478 RGLAFMAPYSTAGLVPTLGF-RPPMDYAFSDLMRDRSAAAAAAVHKEPTYG-GGL--YGP 533
            G+    P +   +VP  G     +    S     ++AA AA     P  G GG+  YG 
Sbjct: 344 VGV----PGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399

Query: 534 MVNGAP 539
              G P
Sbjct: 400 GAGGFP 405



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 126/481 (26%), Positives = 158/481 (32%), Gaps = 95/481 (19%)

Query: 7   LPSVPGAATAAAATATGPPVASVASVAAAAAAAASLPVSVAGGLLRGPPLLLRAAEKYPR 66
           +P VPGA       A    V + A+ AAAAAAA +     A GL+ G P         P 
Sbjct: 282 VPGVPGAIPGIGGIAG---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG 338

Query: 67  TPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQAQEENEA 126
               A     GV                  A   ++       AA   +   +A  +  A
Sbjct: 339 ----AGVPGVGVPG----------------AGIPVVPGAGIPGAAVPGVVSPEAAAKAAA 378

Query: 127 RELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTG----GGAAG 182
           +  +  YG   G+ +          P Y V        G G G G P   G    GG  G
Sbjct: 379 KAAK--YGARPGVGVGGI-------PTYGVGAGGFPGFGVGVG-GIPGVAGVPGVGGVPG 428

Query: 183 AGG-------------SEAKLQKFDLFPKTLLQAG---RPGSPLPPPVKPLSPDGADSGP 226
            GG             + AK  K+ L P   +  G    PG  + P V  L+P G    P
Sbjct: 429 VGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV-GLAP-GVGVAP 486

Query: 227 GTSSPEVRPGSGSENGDGESFSGSPLARASKEAG-GSCPGSAGPGGGGEEDSPGSASP-L 284
           G     V PG G   G G     +    A+K A       +AG G G      G   P L
Sbjct: 487 GVG---VAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 543

Query: 285 GSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVV 344
           G  +G       G  A  PG G   G              PG   G+  L   G  G VV
Sbjct: 544 GVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 600

Query: 345 QAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA 404
                           G GPAA    AA  A AAA  A    V AA       GG G+P 
Sbjct: 601 ----------------GAGPAA----AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG 640

Query: 405 -------PLQAGPAAPPHHRPLLAGAMAPGA---LGSLSSRSAF--SPLQPNASHFGADA 452
                  P  A   A  +    L G +       LG +++R  F  SP+ P  +  G   
Sbjct: 641 VGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKAC 700

Query: 453 G 453
           G
Sbjct: 701 G 701



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 115/429 (26%), Positives = 146/429 (34%), Gaps = 102/429 (23%)

Query: 136 AEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDL 195
           A+     AA G++P  P +   G V     G PGAG P   G G  GAG          +
Sbjct: 311 AKAAKYGAAAGLVPGGPGFGP-GVV-----GVPGAGVP---GVGVPGAG--------IPV 353

Query: 196 FPKTLLQAGRPGSPLPPPVKP---------LSPDGADSGPGTSS-PEVRPGSGSENGDGE 245
            P     AG PG+ +P  V P          +  GA  G G    P    G+G   G G 
Sbjct: 354 VPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409

Query: 246 SFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPG 304
              G P        GG  PG  G PG G   ++  +A+   ++ G           P  G
Sbjct: 410 GVGGIPGVAGVPGVGG-VPGVGGVPGVGISPEAQAAAAAKAAKYG---------LVPGVG 459

Query: 305 LGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGP 364
           +  G G            V PG   GV   V    G  V   +         G+A G+G 
Sbjct: 460 VAPGVG------------VAPGV--GVAPGVGLAPGVGVAPGV---------GVAPGVGV 496

Query: 365 AAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA-----PLQAGPAAPPHHRPL 419
           A       V AAA +     ++    AAA   AG PGL        L  G   P     L
Sbjct: 497 APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP----GL 552

Query: 420 LAGA------MAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAA 473
             GA        PGAL +  +    + +       GA  G    G  +G  P   A +A 
Sbjct: 553 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 612

Query: 474 AAHSR------GLAFMAPYSTAGL----VPTLGFRPPMDYAFSDLMRDRSAAAAAAVHKE 523
           AA         G A +      GL    V  LG  PP            +AAA AA +  
Sbjct: 613 AAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPP------------AAAAKAAKYGA 660

Query: 524 PTYGGGLYG 532
              GG L G
Sbjct: 661 AGLGGVLGG 669


>gi|126352440 elastin isoform a precursor [Homo sapiens]
          Length = 724

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 119/426 (27%), Positives = 154/426 (36%), Gaps = 56/426 (13%)

Query: 138 GLALAAANGIIPPRPAYEVFGSVCAADGGG---PGAGAPAGTGGGAAGAGGSEAKLQKFD 194
           G+ L   + + P RP   V G++     GG   PGAG  A  GGGA G GG   K     
Sbjct: 12  GVLLLLLSILHPSRPG-GVPGAIPGGVPGGVFYPGAGLGA-LGGGALGPGGKPLKPVPGG 69

Query: 195 LFPKTLLQAGRPGSPLPPPVKPLSPDG-ADSGPGTSSPEVRPGSGSENGDGESFSGSPLA 253
           L    L  AG    P       L P G AD+     + +   G G   G G     +   
Sbjct: 70  LAGAGL-GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128

Query: 254 RASKEAG---GSCPGSAGPGGGGEEDSPGS---------ASPLGSESGSEADKEEGEAAP 301
                AG   G  PG   PG       PG+           P G+    +A    G  A 
Sbjct: 129 VPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAG 188

Query: 302 APGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAG 361
            PG+G   GP+   PL      +P     +    L G  G      +    +  GG+A  
Sbjct: 189 IPGVGPFGGPQPGVPLG-----YP-----IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGA 238

Query: 362 LGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPG----LPAPLQAGPAAPPHHR 417
            G A  P    VG  AAA         AAAA AAA  G G    LP    AG    P   
Sbjct: 239 AGKAGYPTGTGVGPQAAA---------AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI 289

Query: 418 PLLAGAMAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSPLRLAYSAAAAHS 477
           P + G    G   + ++ +A +     A+ +GA AG  P G P G  P  +    A    
Sbjct: 290 PGIGGIAGVGTPAAAAAAAAAA----KAAKYGAAAGLVP-GGP-GFGPGVVGVPGAGVPG 343

Query: 478 RGLAFMAPYSTAGLVPTLGF-RPPMDYAFSDLMRDRSAAAAAAVHKEPTYG-GGL--YGP 533
            G+    P +   +VP  G     +    S     ++AA AA     P  G GG+  YG 
Sbjct: 344 VGV----PGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399

Query: 534 MVNGAP 539
              G P
Sbjct: 400 GAGGFP 405



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 91/319 (28%), Positives = 109/319 (34%), Gaps = 58/319 (18%)

Query: 165 GGGPGAG-------------APAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAG---RPGS 208
           GG PG G             A  G G  AA A  + AK  +F L P   +  G    PG 
Sbjct: 430 GGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGVGVAPGV 489

Query: 209 PLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAG-GSCPGSA 267
            + P V  L+P G    PG     V PG G   G G     +    A+K A       +A
Sbjct: 490 GVAPGV-GLAP-GVGVAPGVG---VAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 544

Query: 268 GPGGGGEEDSPGSASP-LGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPG 326
           G G G      G   P LG  +G       G  A  PG G   G              PG
Sbjct: 545 GLGAGIPGLGVGVGVPGLGVGAGVPG---LGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 601

Query: 327 HRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSR 386
              G+  L   G  G VV                G GPAA    AA  A AAA  A    
Sbjct: 602 VLGGLGALGGVGIPGGVV----------------GAGPAA----AAAAAKAAAKAAQFGL 641

Query: 387 VDAAAAAAAAAGGPGLPA-------PLQAGPAAPPHHRPLLAGAMAPGA---LGSLSSRS 436
           V AA       GG G+P        P  A   A  +    L G +       LG +++R 
Sbjct: 642 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 701

Query: 437 AF--SPLQPNASHFGADAG 453
            F  SP+ P  +  G   G
Sbjct: 702 GFGLSPIFPGGACLGKACG 720



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 119/437 (27%), Positives = 152/437 (34%), Gaps = 99/437 (22%)

Query: 136 AEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDL 195
           A+     AA G++P  P +   G V     G PGAG P   G G  GAG          +
Sbjct: 311 AKAAKYGAAAGLVPGGPGFGP-GVV-----GVPGAGVP---GVGVPGAG--------IPV 353

Query: 196 FPKTLLQAGRPGSPLPPPVKP---------LSPDGADSGPGTSS-PEVRPGSGSENGDGE 245
            P     AG PG+ +P  V P          +  GA  G G    P    G+G   G G 
Sbjct: 354 VPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409

Query: 246 SFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGSASPLGSESG-----SEADKEEGEA 299
              G P        GG  PG  G PG G   ++  +A+   ++ G     + A K   +A
Sbjct: 410 GVGGIPGVAGVPGVGG-VPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKA 468

Query: 300 AP---APGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG 356
           A     PG+G   G            V PG   GV   V    G  V   +         
Sbjct: 469 AQFGLVPGVGVAPG----------VGVAPGV--GVAPGVGLAPGVGVAPGV--------- 507

Query: 357 GLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPA-----PLQAGPA 411
           G+A G+G A       V AAA +     ++    AAA   AG PGL        L  G  
Sbjct: 508 GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAG 567

Query: 412 APPHHRPLLAGA------MAPGALGSLSSRSAFSPLQPNASHFGADAGAYPLGAPLGLSP 465
            P     L  GA        PGAL +  +    + +       GA  G    G  +G  P
Sbjct: 568 VP----GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 623

Query: 466 LRLAYSAAAAHSR------GLAFMAPYSTAGL----VPTLGFRPPMDYAFSDLMRDRSAA 515
              A +A AA         G A +      GL    V  LG  PP            +AA
Sbjct: 624 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPP------------AAA 671

Query: 516 AAAAVHKEPTYGGGLYG 532
           A AA +     GG L G
Sbjct: 672 AKAAKYGAAGLGGVLGG 688


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 77/293 (26%), Positives = 93/293 (31%), Gaps = 68/293 (23%)

Query: 162 AADGGGPGAGAPAGTGG-----------------GAAGAGGSEAKLQKFDLFPKTLLQAG 204
           A + G PG   P G  G                 G+ G  GS+ K       P +  ++G
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP----PGSQGESG 561

Query: 205 RPGSPLPPPVKPLSPDGADSGPGTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSC 263
           RPG P   P  P    G    PG    +  PG +G   G G      P  +  +      
Sbjct: 562 RPGPP--GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGP 619

Query: 264 PGSAGPGGG----------GEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSG--- 310
           PG  GPGG           G +  PG+  P G E+G   +      A APG  GG G   
Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-ENGKPGEPGPKGDAGAPGAPGGKGDAG 678

Query: 311 -PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPD 369
            P +R P  +     PG R G       G  G              GG  A  GP  PP 
Sbjct: 679 APGERGPPGLAGA--PGLRGGA------GPPGP------------EGGKGAA-GPPGPPG 717

Query: 370 KAAV-------GAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPP 414
            A         G         P           A G PG   P    GP  PP
Sbjct: 718 AAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 87/322 (27%), Positives = 108/322 (33%), Gaps = 64/322 (19%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP----LPPPVKPLSP 219
           G PG   P+G  G  GA G  G   K            ++GRPG P    LP P     P
Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDG----------ESGRPGRPGERGLPGPPGIKGP 253

Query: 220 DGADSGPGTSSPEVRPGSGSENGD-------GESF----SGSPLARASKEAGGS-----C 263
            G    PG        G   E G+       GE+     +G+P     + A G       
Sbjct: 254 AGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL 313

Query: 264 PGSAGPGGG----GEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDI 319
           PG+AG  G     G +  PG   P G+     +   +GE  PA   G    P QR     
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE--- 370

Query: 320 LTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAA 379
                PG          QG  G         +N   GG    +GPA  P   A G   A 
Sbjct: 371 -----PGP---------QGHAGAQGPPGPPGINGSPGG-KGEMGPAGIP--GAPGLMGAR 413

Query: 380 DDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSA-F 438
               P+  + A      AG PG     + G    P  R     A  PG  G+        
Sbjct: 414 GPPGPAGANGAPGLRGGAGEPG-----KNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468

Query: 439 SPLQPNASHFGADAGAYPLGAP 460
           SP +P A+  G    A   GAP
Sbjct: 469 SPGEPGAN--GLPGAAGERGAP 488



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 83/312 (26%), Positives = 101/312 (32%), Gaps = 69/312 (22%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLS----- 218
            G PGA  P G  G  GA G  G                  G  GSP P  VK  S     
Sbjct: 939  GPPGAPGPLGIAGITGARGLAGPPG-------------MPGPRGSPGPQGVKGESGKPGA 985

Query: 219  --------PDGADSGPGTSSPEVRPG-SGSENGDG-ESFSGSPLARASKEAGGSCPGSAG 268
                    P G    PG +     PG  G+   DG     GSP  +  +   GS      
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGS------ 1039

Query: 269  PGGGGEEDSPGSASPLGSESGSEADKEEGEAAPA--------PGLGGGSGPR-------Q 313
            PG  G    PG   P+G    S    E G A PA         G  G  GPR       +
Sbjct: 1040 PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGE 1099

Query: 314  RTPLDIL-TRVFPGHRRGVLELVLQGCGGDVVQAIEQ--VLNHHRGGLAAGLGPAAPPDK 370
            R    I   R FPG+          G  G    A +Q  + +    G    +GP+ PP K
Sbjct: 1100 RGAAGIKGHRGFPGN---------PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGK 1150

Query: 371  AAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALG 430
               G +       P           + G PG P   Q GP  PP       G +   A+ 
Sbjct: 1151 D--GTSGHPGPIGPPGPRGNRGERGSEGSPGHPG--QPGPPGPPGAPGPCCGGVGAAAIA 1206

Query: 431  SLSSRSA--FSP 440
             +    A  F+P
Sbjct: 1207 GIGGEKAGGFAP 1218



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 79/284 (27%), Positives = 96/284 (33%), Gaps = 52/284 (18%)

Query: 162 AADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSP 219
           A   G PG   PAG  G  G AG  G+  +  + D  P      G PGSP  P       
Sbjct: 494 AGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR-DGVPGGPGMRGMPGSPGGP-----GS 547

Query: 220 DGADSGPGTSSPEVRPGSGSENGDG--ESFSGSPLARASKEAGGSCPGSAGPGGGGEEDS 277
           DG    PG+     RPG    +G        G P  + +  A G      GPGG G +  
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607

Query: 278 PGS---ASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLEL 334
           PG      P G    +    ++G+  P PG  G  G                        
Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGP-PGPQGLQG------------------------ 642

Query: 335 VLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAA 394
            L G GG   +  +      +G   A   P AP  K   G A A  +  P  +   A A 
Sbjct: 643 -LPGTGGPPGENGKPGEPGPKGDAGA---PGAPGGK---GDAGAPGERGPPGL---AGAP 692

Query: 395 AAAGGPGLPAPLQAGPAAPPHHRPLLAGAMA----PGALGSLSS 434
              GG G P P     AA P   P  AG       PG  G L S
Sbjct: 693 GLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 93/339 (27%), Positives = 109/339 (32%), Gaps = 61/339 (17%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRP 206
            PP PA +          G PG   P G+ G  G  G  G          FP    Q G P
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG-------FPGAPGQNGEP 821

Query: 207  GSP----LPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGD-----GESFSGSPLARASK 257
            G       P       P G    PG S P   PG     G+     G   +G P AR   
Sbjct: 822  GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLP 881

Query: 258  EAGGS--CPGSAGPGGG-GEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSG---- 310
               GS   PG  GP G  G++  PG A   G+         +G+A   PG  G  G    
Sbjct: 882  GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG-QPGEKGSPGAQGP 940

Query: 311  PRQRTPLDILTRV----------FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG---- 356
            P    PL I               PG R        QG  G+  +     L+  RG    
Sbjct: 941  PGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP---QGVKGESGKPGANGLSGERGPPGP 997

Query: 357  -GLAAGLGPAAPPDKAAVGAAAAADDAWPSR-----------VDAAAAAAAAAGGPGLPA 404
             GL    G A  P +          D  P R            + +  A  A G PG P 
Sbjct: 998  QGLPGLAGTAGEPGR----DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG 1053

Query: 405  PLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQP 443
            P+  GPA     R     A   GA G   SR A  P  P
Sbjct: 1054 PV--GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP 1090



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 76/300 (25%), Positives = 96/300 (32%), Gaps = 74/300 (24%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
           GGPGA    G  G  G  G  G      +    P    + G PG  LP    P    G  
Sbjct: 747 GGPGADGVPGKDGPRGPTGPIGPPGPAGQ----PGDKGEGGAPG--LPGIAGPRGSPGER 800

Query: 224 SGPGTSSPEVRPGSGSENGD--GESFSGSPLARASKEAGGSCPGSAGPGGG--------- 272
              G   P   PG+  +NG+  G+   G+P     ++  G  PG AGP GG         
Sbjct: 801 GETGPPGPAGFPGAPGQNGEPGGKGERGAP----GEKGEGGPPGVAGPPGGSGPAGPPGP 856

Query: 273 ----GEEDSPG--------SASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDIL 320
               GE  SPG         A  L    GS  +      + +PG  G  GP   T     
Sbjct: 857 QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA--- 913

Query: 321 TRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAAD 380
               PG         + G  GD  Q                     P +K + GA     
Sbjct: 914 ----PGSPG------VSGPKGDAGQ---------------------PGEKGSPGAQGPPG 942

Query: 381 DAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSP 440
              P  +     A   AG PG+P     GP   P  + +   +  PGA G    R    P
Sbjct: 943 APGPLGIAGITGARGLAGPPGMP-----GPRGSPGPQGVKGESGKPGANGLSGERGPPGP 997



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 74/280 (26%), Positives = 90/280 (32%), Gaps = 59/280 (21%)

Query: 166 GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSP-LPPPVKPLSPDGA 222
           G PG    AG  G  G  G  GS     K ++ P     AG PG+P L     P  P GA
Sbjct: 369 GEPGPQGHAGAQGPPGPPGINGSPGG--KGEMGP-----AGIPGAPGLMGARGPPGPAGA 421

Query: 223 DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAG-------------- 268
           +  PG     +R G+G    +G      P     +      PG+ G              
Sbjct: 422 NGAPG-----LRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN 476

Query: 269 --PGGGGEEDSPGSASPLGSESGSEADK----EEGEAAPAPGLGGGSGP-RQRTPLDILT 321
             PG  GE  +PG   P G  +G   +K    E G   PA   G    P R   P     
Sbjct: 477 GLPGAAGERGAPGFRGPAG-PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGM 535

Query: 322 RVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADD 381
           R  PG   G       G  G          +    G     GP+ P  +  V        
Sbjct: 536 RGMPGSPGGPGSDGKPGPPG----------SQGESGRPGPPGPSGPRGQPGVMGFPG--- 582

Query: 382 AWPSRVDAAAAAAAAAGGPGLPAPL-------QAGPAAPP 414
             P   D A       GGPG P P        + GP  PP
Sbjct: 583 --PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPP 620



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 86/323 (26%), Positives = 105/323 (32%), Gaps = 37/323 (11%)

Query: 157 FGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAK--LQKFDLFPKTLLQAGRPGSPLPPPV 214
           FG  CA     P A      G G  G  G      +   +  P    Q G PGSP PP +
Sbjct: 81  FGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI 140

Query: 215 KPLSPDGADS-GPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAG-PGGG 272
               P G  +  P   S +V+ G       G      P            PGS G PG  
Sbjct: 141 CESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQ 200

Query: 273 GEEDSPGSASPLG--------SESGSEADKEEGEAAPAPGLGGGSGPRQ-RTPLDILTRV 323
           G    PG A P G          SG      E      PG  G  GP   + P  I    
Sbjct: 201 GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGI--PG 258

Query: 324 FPGHR--RGVLELVLQGCGGDVVQAIEQVLNHHRG-----GLAAGLGP-AAPPDKAAVGA 375
           FPG +  RG       G  G+  +     L    G     G    +GP  AP ++   G 
Sbjct: 259 FPGMKGHRG-----FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL 313

Query: 376 AAAADDAWPSRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSR 435
             AA        D A  +    G PG P    AG    P  +  +  A +PG+ G+   R
Sbjct: 314 PGAAG---ARGNDGARGSDGQPGPPGPPG--TAGFPGSPGAKGEVGPAGSPGSNGAPGQR 368

Query: 436 SAFSPLQPNASHFGADAGAYPLG 458
               P      H GA     P G
Sbjct: 369 GEPGP----QGHAGAQGPPGPPG 387



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/156 (30%), Positives = 54/156 (34%), Gaps = 34/156 (21%)

Query: 162  AADGGGPGAGAPAGTGG-----GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKP 216
            A   G PG   P G  G     GAAG  G          FP      G PG+P  P   P
Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRG-------FP------GNPGAPGSPG--P 1123

Query: 217  LSPDGADSGPGTSSPEVRPG-SGSENGDGESFSGSPLA----RASKEAGGSCPGSAGPGG 271
                GA   PG + P    G SG    DG S    P+     R ++   GS      PG 
Sbjct: 1124 AGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQ 1183

Query: 272  GGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGG 307
             G    PG+  P     G         AA   G+GG
Sbjct: 1184 PGPPGPPGAPGPCCGGVG---------AAAIAGIGG 1210


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 78/286 (27%), Positives = 92/286 (32%), Gaps = 42/286 (14%)

Query: 164  DGGGPGAGAPAGTGG--GAAGAGGSEAK--LQKFDLFPKTLLQAGRPGSPLPP----PVK 215
            D G PG     G  G  G  G  G E K  LQ     P  +   G PG P  P    P  
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 216  PLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEE 275
            P  P G    PG + P   PG G     G      P   +        PG   PG  GE 
Sbjct: 2199 PQGPSGLKGEPGETGP---PGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGL--PGQVGET 2253

Query: 276  DSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELV 335
              PG+    G+ SG + D+       +PGL G  GP+            P    G   + 
Sbjct: 2254 GKPGAPGRDGA-SGKDGDRGSPGVPGSPGLPGPVGPKGEPG--------PTGAPGQAVVG 2304

Query: 336  LQGCGGDVVQAIEQVLNHHRGGLAAGLG-----------PAAPPDKAAVGAAAAADDAWP 384
            L G  G+             GGLA  L            P    +K   G A    D   
Sbjct: 2305 LPGAKGE---------KGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGE 2355

Query: 385  SRVDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALG 430
                 A       G PG+  P   GP  PP  +  L     PGA G
Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 85/328 (25%), Positives = 101/328 (30%), Gaps = 87/328 (26%)

Query: 166  GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK---------- 215
            G  GA  P G  G A   G  E      D  P +  +AG PG+P  P +K          
Sbjct: 1278 GRTGAPGPQGPPGSATAKG--ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335

Query: 216  ------PLSPDGADSGPGTSSPEVRPGSGSENGD----GESFSGSPLARASKEAGGSCPG 265
                  P  P G    PG       PG     GD    G      PL           PG
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 266  SA--------------GPGGG----------GEEDSPGSASPLG--SESGSEADKEEGEA 299
            +A              GPG G          G   SPG   P+G   + G + D E+G  
Sbjct: 1396 TAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDG-- 1453

Query: 300  APAPGLGGGSG-PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG-- 356
              APGL G  G P ++ P      + P   RG       G  G+  +  E+      G  
Sbjct: 1454 --APGLPGQPGSPGEQGPRGPPGAIGPKGDRG-----FPGPLGEAGEKGERGPPGPAGSR 1506

Query: 357  ------GLAAGLGPAAPP----------------DKAAVGAAAAA-----DDAWPSRVDA 389
                  G     GP  PP                D A VG A A       D  P+    
Sbjct: 1507 GLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRG 1566

Query: 390  AAAAAAAAGGPGLPAPLQAGPAAPPHHR 417
            A       G PGL  P   GP   P  R
Sbjct: 1567 ATGVQGERGPPGLVLPGDPGPKGDPGDR 1594



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 72/269 (26%), Positives = 88/269 (32%), Gaps = 42/269 (15%)

Query: 202  QAGRPGSP-LPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAG 260
            Q G PG   L   V P    G     G   P+  PGS +  G+     G P A     + 
Sbjct: 1255 QKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGE----RGFPGADGRPGSP 1310

Query: 261  GSCPGSAGPGGGGEEDSPGSASPLG--SESGSEADKEE---------GEAAPAPGLGGGS 309
            G       PG  G + SPG   P G   E G    K E         GE    PG  G  
Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDP 1370

Query: 310  GPR----QRTPLDILTRVFPGHR--RGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLG 363
            GP      R PL       PG R   G+    ++G  GD            RG    G G
Sbjct: 1371 GPSGPPGPRGPLG-----DPGPRGPPGLPGTAMKGDKGD---------RGERGPPGPGEG 1416

Query: 364  PAAPPDKAAVGAAAAADDAWP-----SRVDAAAAAAAAAGGPGLP-APLQAGPAAPPHHR 417
              AP +    G   +     P      + +   +   A G PG P +P + GP  PP   
Sbjct: 1417 GIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI 1476

Query: 418  PLLAGAMAPGALGSLSSRSAFSPLQPNAS 446
                    PG LG    +    P  P  S
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGS 1505



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 46/148 (31%), Positives = 56/148 (37%), Gaps = 23/148 (15%)

Query: 166  GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
            G PGA  P+G  G AAG  G   +    D  P    + G PG P  PP  P  P G D  
Sbjct: 1785 GKPGAAGPSGPNG-AAGKAGDPGR----DGLPGLRGEQGLPG-PSGPPGLPGKP-GEDGK 1837

Query: 226  PGTSSPEVRPGSGSENG-DGESFSGSPLARASKE-------AGG--------SCPGSAGP 269
            PG +     PG   E+G  GE        R  ++       A G          PG  GP
Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGP 1897

Query: 270  GGGGEEDSPGSASPLGSESGSEADKEEG 297
             G G    PG   P G    + +  E+G
Sbjct: 1898 PGQGFPGVPGGTGPKGDRGETGSKGEQG 1925



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 95/347 (27%), Positives = 113/347 (32%), Gaps = 65/347 (18%)

Query: 166  GGPGAGAPAGTGG--------GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPL 217
            G PG   P G  G        G AG  G E         P  L   G PGS  PP    L
Sbjct: 2404 GFPGQTGPRGEMGQPGPSGERGLAGPPGREG-------IPGPLGPPGPPGSVGPPGASGL 2456

Query: 218  SPDGADSG---PGTSSPEVRPGSGSENG-----DGESFSGSPLARASKEAGGSCPGSAGP 269
              D  D G   PG       PG   E+G          +G P +R  +   G   GSAG 
Sbjct: 2457 KGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDV-GSAGL 2515

Query: 270  GGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPR--QRTPLDILTRVFPGH 327
             G    D   SA  LG      A  + GE  P  GL G  GPR     P D  ++  PG 
Sbjct: 2516 KG----DKGDSAVILGPPGPRGAKGDMGERGPR-GLDGDKGPRGDNGDPGDKGSKGEPGD 2570

Query: 328  R--------RGVL----ELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPPDKAAV 373
            +        RG+L    +    G  GD     +  +   RG  G    +GP     +  V
Sbjct: 2571 KGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV 2630

Query: 374  GAAAAAD-------DAWPSRVDAAAAAAAAAGGPGLP----APLQAGPAAPPHHRPLLAG 422
              A   D       +A P      A      G PG+P    AP + G   P   R     
Sbjct: 2631 KGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ 2690

Query: 423  AMAPGALGSLSSRSAFSPLQPNASHF----GADAGAYPLGAPLGLSP 465
                G  G    R       P    F    G D  A P G P  + P
Sbjct: 2691 PGPKGDQGEKGERGT-----PGIGGFPGPSGNDGSAGPPGPPGSVGP 2732



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 71/265 (26%), Positives = 90/265 (33%), Gaps = 26/265 (9%)

Query: 162  AADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLL----QAGRPGSPLPPPVKPL 217
            A + G  G   PAG+ G    AG   AK  +    P        + GRPG P        
Sbjct: 1491 AGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550

Query: 218  SPDGADSGPGTSSPEVRPGSGSENGD-GESFSGSPLARASKEAGGSC--------PGSAG 268
             P G     G + P    G   E G  G    G P  +      G          PG +G
Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG 1610

Query: 269  PGGG-GEEDSPGSASPLGSESGSEADKEEGEAAPA--PGLGGGSGPRQRTPLDILTRVFP 325
            P G  G+   PG   P+G         E+G+  P   PGL G +G R         R  P
Sbjct: 1611 PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERG-------LRGAP 1663

Query: 326  GHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPS 385
            G R  V E   QG  G+  +      +  +G      GP  PP +       A +   P 
Sbjct: 1664 GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP-GPPGPPGRLVDTGPGAREKGEPG 1722

Query: 386  RVDAAAAAAAAAGGPGLP-APLQAG 409
                        G PGLP AP + G
Sbjct: 1723 D-RGQEGPRGPKGDPGLPGAPGERG 1746



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 48/180 (26%), Positives = 57/180 (31%), Gaps = 40/180 (22%)

Query: 166  GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPP-PVKPLSPDGADS 224
            G PG   P G  G A G  G          FP  L +AG  G   PP P       G   
Sbjct: 1462 GSPGEQGPRGPPG-AIGPKGDRG-------FPGPLGEAGEKGERGPPGPAGSRGLPGVAG 1513

Query: 225  GPGTSSPEVRPGSGSENGD------------------------GESFSGSPLARASKEAG 260
             PG   PE  PG     G+                        G+     P      +  
Sbjct: 1514 RPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGE 1573

Query: 261  GSCPGSAGPGGGGEEDSPGSASPLG--SESGSEADK----EEGEAAPAPGLGGGSGPRQR 314
               PG   PG  G +  PG   P+G    +G   D     E+G+    PG  G  GPR R
Sbjct: 1574 RGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPG-RPGPPGPVGPRGR 1632



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 88/345 (25%), Positives = 109/345 (31%), Gaps = 61/345 (17%)

Query: 138  GLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFP 197
            GLAL       PP P      S  A + G PG     G  GG   AG    + ++ +   
Sbjct: 2018 GLALGERG---PPGP------SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGE 2068

Query: 198  KTLLQAGRPGSPLPPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGES-FSGSPLARAS 256
            +   + GR G P           G    PG   P     S  E G G S   G P  + +
Sbjct: 2069 RG--EQGRDGPP-----------GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA 2115

Query: 257  KEAGGSCPGSAGPGGG----GEEDSPGSASPLGSESGSEADKEEGEAAP--APGLGGGSG 310
            K   GS  G  GP G     G +   G   P G +       E G A P   PGL G  G
Sbjct: 2116 KGEPGS-NGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRG 2174

Query: 311  PRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDK 370
            P             PG   G  +    G  G    A  Q       GL    G   PP +
Sbjct: 2175 P-------------PGPVGGHGDPGPPGAPGLAGPAGPQ----GPSGLKGEPGETGPPGR 2217

Query: 371  AAVGAAAAADDAWPSRVDAAAAAAAAAGGPGLP----------APLQAGPAAPPHHRPLL 420
               G   A     P      +      G PGLP          AP + G +     R   
Sbjct: 2218 GLTGPTGAVGLPGP---PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSP 2274

Query: 421  AGAMAPGALGSLSSRSAFSPL-QPNASHFGADAGAYPLGAPLGLS 464
                +PG  G +  +    P   P  +  G        GAP GL+
Sbjct: 2275 GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 49/171 (28%), Positives = 57/171 (33%), Gaps = 40/171 (23%)

Query: 164  DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDG 221
            D G PGA    G  G  G  G  G           P     AG  G   PP +   S  G
Sbjct: 1735 DPGLPGAPGERGIEGFRGPPGPQGD----------PGVRGPAGEKGDRGPPGLDGRS--G 1782

Query: 222  ADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGP------------ 269
             D  PG + P    G+  + GD     G P  R  +      PG +GP            
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGD-PGRDGLPGLRGEQ----GLPGPSGPPGLPGKPGEDGK 1837

Query: 270  ----GGGGEEDSPGSASPLGSESGSEADKEEGEAAP-----APGLGGGSGP 311
                G  GE   PG     G +  S A   EG   P     APG+ G  GP
Sbjct: 1838 PGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGP 1888



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 68/258 (26%), Positives = 81/258 (31%), Gaps = 29/258 (11%)

Query: 166  GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
            G PG   P G  G     G            PK     G PG P PP          D+G
Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKG--DRGEPGPPGPPGRL------VDTG 1712

Query: 226  PGT---SSPEVRPGSGSENGDGE-SFSGSPLARASKEAGGSCPGSAG-PGGGGEEDSPGS 280
            PG      P  R   G     G+    G+P  R  +   G  PG  G PG  G     G 
Sbjct: 1713 PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGP-PGPQGDPGVRGPAGEKGD 1771

Query: 281  ASPLGSESGSEADKEEGEAAPA--PGLGGGSGPRQRTPLDIL--TRVFPGHRRGVLELVL 336
              P G +  S  D + G A P+   G  G +G   R  L  L   +  PG          
Sbjct: 1772 RGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP------ 1825

Query: 337  QGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSRVDAAAAAAAA 396
             G  G   +  +  LN   G            +K   GA+       P     A      
Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGP 1885

Query: 397  AGGPGLPAPLQAGPAAPP 414
             G PGLP     GP  PP
Sbjct: 1886 QGPPGLP-----GPVGPP 1898



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 47/199 (23%), Positives = 58/199 (29%), Gaps = 25/199 (12%)

Query: 149  PPRPAYEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGS 208
            PP P     G +   + G PG     G  G     G    K    D  P    Q G PG 
Sbjct: 1410 PPGPGE---GGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGE 1466

Query: 209  P----------------LPPPVKPLSPDGADSGPGTSSPEVRPG-SGSENGDGESFSGSP 251
                              P P+      G    PG +     PG +G     G      P
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP 1526

Query: 252  LARASKEAGGSCPGS---AGPGGGGEEDSPGSASPLGSESGSEADKEEG-EAAPAPGLGG 307
              R  ++     PG     GP   G +   G   P G    +    E G      PG  G
Sbjct: 1527 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPG 1586

Query: 308  GSG-PRQRTPLDILTRVFP 325
              G P  R P+ +  R  P
Sbjct: 1587 PKGDPGDRGPIGLTGRAGP 1605



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 52/171 (30%), Positives = 57/171 (33%), Gaps = 29/171 (16%)

Query: 164  DGGGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PLSPD 220
            D G PG   P G  G  G  G  G E       L  K    AG  G    P V+ P+   
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGK----AGERGLRGAPGVRGPVGEK 1672

Query: 221  GADSGPGTSSPEVRPGSGSENGD-GESFSGSPLARASKEAGGSC----PGSAG------- 268
            G    PG       PGS    GD GE     P  R      G+     PG  G       
Sbjct: 1673 GDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGP 1732

Query: 269  ------PGGGGE---EDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSG 310
                  PG  GE   E   G   P G         E+G+  P PGL G SG
Sbjct: 1733 KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP-PGLDGRSG 1782



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 46/149 (30%), Positives = 51/149 (34%), Gaps = 17/149 (11%)

Query: 166  GGPGAGAPAGTGGGAAG--AGGSEAKLQKFDLFPKTLL-QAGRPGSPLPPPVKPLSPDGA 222
            G PGA    G  GG AG   G   AK  +    P+    +AGR G P  P       DG 
Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDP-----GEDGQ 2358

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
               PG    +  PG G     G    G P  +      G       PG  G    PG   
Sbjct: 2359 KGAPGPKGFKGDPGVGVPGSPGPP--GPPGVKGDLGLPGL------PGAPGVVGFPGQTG 2410

Query: 283  PLGSESGSEADKEEGEAAPAPGLGGGSGP 311
            P G         E G A P PG  G  GP
Sbjct: 2411 PRGEMGQPGPSGERGLAGP-PGREGIPGP 2438



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 77/295 (26%), Positives = 97/295 (32%), Gaps = 81/295 (27%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG     G  G  GA+G  G +    +    P  L   G PG  LP PV P       
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGA-PGILGPQGPPG--LPGPVGP------- 1897

Query: 224  SGPGTSSPEVRPGSGSENGDGESFS----GSPLARASKEAGGSCPG-------------- 265
              PG   P V  G+G +   GE+ S    G P  R  +   GS P               
Sbjct: 1898 --PGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASA 1955

Query: 266  ---------------------SAGP-GGGGEEDSPGSASPLG--SESGSEADKEE----- 296
                                   GP G  GE+  PG   P+G   E G + D+ +     
Sbjct: 1956 LREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQG 2015

Query: 297  ------GEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQV 350
                  GE  P PG  G +G   +  +  L    PG   GV E    G  G+  +  E+ 
Sbjct: 2016 PPGLALGERGP-PGPSGLAGEPGKPGIPGL----PGRAGGVGEAGRPGERGERGEKGERG 2070

Query: 351  LNHHRG--GLAAGLGPAAPPDKAAVGAAAAADDAWP--SRVDAAAAAAAAAGGPG 401
                 G  GL    GP  PP     G   + D+  P  S          A G PG
Sbjct: 2071 EQGRDGPPGLPGTPGPPGPP-----GPKVSVDEPGPGLSGEQGPPGLKGAKGEPG 2120



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 42/138 (30%), Positives = 47/138 (34%), Gaps = 45/138 (32%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPP-PVKPLSPDGA 222
            G PG     G  G  G  G GG          FP      G  G P PP  V P  P+G 
Sbjct: 2689 GQPGPKGDQGEKGERGTPGIGG----------FPGPSGNDGSAGPPGPPGSVGPRGPEGL 2738

Query: 223  DSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSAS 282
                G   P            GE   G+P            PG+  PG  GE+  PG A 
Sbjct: 2739 QGQKGERGPP-----------GERVVGAP----------GVPGA--PGERGEQGRPGPAG 2775

Query: 283  PLGSESGSEADKEEGEAA 300
            P G         E+GEAA
Sbjct: 2776 PRG---------EKGEAA 2784



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 45/161 (27%), Positives = 53/161 (32%), Gaps = 38/161 (23%)

Query: 161  CAADG--GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLS 218
            C  DG  G  G   P G  G  AG  G   +       P    Q+G PG      + P  
Sbjct: 2634 CGLDGEKGDKGEAGPPGRPG-LAGHKGEMGE-------PGVPGQSGAPGKE--GLIGPKG 2683

Query: 219  PDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSP 278
              G D  PG        G   E G+          R +   GG    S   G  G    P
Sbjct: 2684 DRGFDGQPGPK------GDQGEKGE----------RGTPGIGGFPGPSGNDGSAGPPGPP 2727

Query: 279  GSASPLGSESGSEADKEEGEAAP-------APGLGGGSGPR 312
            GS  P G E       ++GE  P       APG+ G  G R
Sbjct: 2728 GSVGPRGPEG---LQGQKGERGPPGERVVGAPGVPGAPGER 2765


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 87/302 (28%), Positives = 99/302 (32%), Gaps = 62/302 (20%)

Query: 166  GGPGAGAPAGTGG-----------GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPV 214
            G PG   P G  G           GA G  G+E         P     AG PG     P 
Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP-------PGPPGPAGSPGER--GPA 1095

Query: 215  KPLSPDGADSGPGTSSPEVRPGSGSENG-DGESFSGSPLARASKEAGGSCPGSAGP-GGG 272
                P G    PG   P   PG   E G  GE     P  R   +     PG AGP G  
Sbjct: 1096 GAAGPIGIPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPP 1152

Query: 273  GEEDSPGSASPLGSESGSEADK-EEGEAAPA-----------PGLGGGSGPRQRTPL--- 317
            GE+   G     G + GS+ DK E+G   P             G  G  GPR +  L   
Sbjct: 1153 GEDGDKGEIGEPG-QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQ 1211

Query: 318  --DILTRVFPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGA 375
              D   R FPG    V    LQG  G   +  E        G    +GP  PP       
Sbjct: 1212 KGDEGPRGFPGPPGPV---GLQGLPGPPGEKGET-------GDVGQMGPPGPPGPRGPSG 1261

Query: 376  AAAAD--DAWPSRVDAAAAAA-----AAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGA 428
            A  AD     P  +    A         AG PGLP   + GP  P   R     +   GA
Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPG--EGGPPGPKGERGEKGESGPSGA 1319

Query: 429  LG 430
             G
Sbjct: 1320 AG 1321



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 48/179 (26%), Positives = 60/179 (33%), Gaps = 37/179 (20%)

Query: 166 GGPGAGAPAGT---------GGGAAGAGGSEAKLQKFDLFPKTLLQAGR-----PGSPL- 210
           G  G   P GT         GGG AG+ G     Q+     + +LQ  R     P  P+ 
Sbjct: 508 GADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQA--QAILQQARLALRGPAGPMG 565

Query: 211 ----PPPVKPLSPDGADSGPGTSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGS 266
               P PV P    G    PG   P+     G +   G +       RA  +     PG 
Sbjct: 566 LTGRPGPVGPPGSGGLKGEPGDVGPQ--GPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQ 623

Query: 267 AGPGGG-------------GEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPR 312
            GP G              G    PG + P G         ++GE  P  GL G  GPR
Sbjct: 624 TGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPR-GLPGEPGPR 681



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 67/253 (26%), Positives = 79/253 (31%), Gaps = 50/253 (19%)

Query: 166  GGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSG 225
            G PGA  P G  GG    G    K +     P    + G PG   PP  K    +  +SG
Sbjct: 1261 GAPGADGPQGPPGGIGNPGAVGEKGE-----PGEAGEPGLPGEGGPPGPKGERGEKGESG 1315

Query: 226  P-GTSSPEVRPG-SGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGSASP 283
            P G + P   PG  G    DG   S  P+           PG  GP G  E    G   P
Sbjct: 1316 PSGAAGP---PGPKGPPGDDGPKGSPGPVG---------FPGDPGPPG--EPGPAGQDGP 1361

Query: 284  LGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDV 343
             G +       + G   P  G  G SGP             PG R        +G  G+ 
Sbjct: 1362 PGDKGDDGEPGQTGSPGPT-GEPGPSGP-------------PGKRGPPGPAGPEGRQGE- 1406

Query: 344  VQAIEQVLNHHRGGLAAGLGPAAPPDKAA-VGAAAAADDAWPSRVDAAAAAAAAAGGPGL 402
                         G     G   PP K   +G   A     P  +          G PG 
Sbjct: 1407 ------------KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454

Query: 403  PAP-LQAGPAAPP 414
            P P    GP  PP
Sbjct: 1455 PGPDGPPGPMGPP 1467



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 78/298 (26%), Positives = 105/298 (35%), Gaps = 40/298 (13%)

Query: 166 GGPGAGAPAGTGGGAAGAGGSEAKLQKFDL----FPKTLL-QAGRPGSPLPPPVKPLSPD 220
           G PG   P G  G   G  G + ++    L     P+ LL   G PG P PP V  +  D
Sbjct: 646 GDPGPSGPPGPPGDD-GERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGM--D 702

Query: 221 GADSGPGTSSPEVRPGSGSENGD--GESFSGSPLARASKEAGGSC--PGSAG-PGGGGEE 275
           G     G   P+  PG   + G+   +   G   A       G    PG  G PG  G  
Sbjct: 703 GQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP 762

Query: 276 DSPGSASPLGSESGSEADKEEGEAA-PAP-GLGGGSGPR--QRTPLDILTRVFPGHRRGV 331
             PG   P G + G      +G    P P G+ G  G R  + T  +     FPG +   
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG-- 820

Query: 332 LELVLQGCGGDVVQAIEQVLN-----HHRGGLAAGLGPAAPP-DKAAVGAAAAADDAWPS 385
            ++ ++G  G++     +  +       RGG     GP  PP +K  +G        +P 
Sbjct: 821 -DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL--PGYPG 877

Query: 386 R-----------VDAAAAAAAAAGGPGLPAPL-QAGPAAPPHHRPLLAGAMAPGALGS 431
           R              A       G PG P P  Q GP  P   R        PG  G+
Sbjct: 878 RQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGN 935



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 66/271 (24%), Positives = 80/271 (29%), Gaps = 67/271 (24%)

Query: 164  DGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVK-PLSPDGA 222
            D G PG   PAG  G     G                 + G+ GSP P     P  P G 
Sbjct: 1346 DPGPPGEPGPAGQDGPPGDKGDDG--------------EPGQTGSPGPTGEPGPSGPPGK 1391

Query: 223  DSGPGTSSPEVRPGSGSENGDG--------------ESFSGSPLARASKEAGG-----SC 263
               PG + PE R G     G+               +   G P     +   G       
Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGL 1451

Query: 264  PGSAGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRV 323
            PGS GP G      P     L  +SG + +K        PGL G  GP            
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGH------PGLIGLIGP------------ 1493

Query: 324  FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAW 383
             PG +    +  L G  G      EQ       G+    GP  PP     G         
Sbjct: 1494 -PGEQGEKGDRGLPGPQGSSGPKGEQ-------GITGPSGPIGPP-----GPPGLPGPPG 1540

Query: 384  PSRVDAAAAAAAAAGGPGLPAPLQAGPAAPP 414
            P     ++      G  G P P   GP  PP
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGP--PGPPGPP 1569



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 83/335 (24%), Positives = 99/335 (29%), Gaps = 48/335 (14%)

Query: 166  GGPGAGAPAGTGG--GAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGAD 223
            G PG   P G  G  G  GA G             T  + G  G P       +  D  +
Sbjct: 778  GPPGPQGPIGYPGPRGVKGADGIRG-------LKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 224  SGP----GTSSPEVRPGSGSENGDGESFSGSPLARASKEAGG--SCPGSAGPGGG----- 272
             GP    G   PE   G G  NGD     G P  +      G    PG  GP G      
Sbjct: 831  IGPPGPRGEDGPEGPKGRGGPNGDPGPL-GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG 889

Query: 273  --------GEEDSPGSASPLGSESGSEADKEEGEAA----PAP-GLGGGSGP----RQRT 315
                    G   +PG   P G    +    E G       P P G  GG GP     +R 
Sbjct: 890  FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949

Query: 316  PLDILTRV-FPGHRRGVLELVLQGCGGDVVQAIEQVLNHHRG--GLAAGLGPAAPP-DKA 371
            P        FPG +         G  G   Q  E       G  G    +GP  P  +  
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 372  AVGAAAAADDAWPSRVDAAAAAAAAAGGPGLPAPL-QAGPAAPPHHRPLLAGAMAPGALG 430
             +G         P         A   G  G P P    G   PP  R        PG +G
Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069

Query: 431  SLSSRSAFSPLQP-----NASHFGADAGAYPLGAP 460
            +L  +    P  P     +    G    A P+G P
Sbjct: 1070 ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 71/262 (27%), Positives = 86/262 (32%), Gaps = 51/262 (19%)

Query: 169 GAGAPAGTGGGAAGAGGSEA-KLQKFDLFPKTLLQAGRPGSPLPPPVKPLSPDGADSGPG 227
           G G PA       G GG    K QK +  P  +     PG  +  P  P  P G    PG
Sbjct: 431 GPGMPANQDTIYEGIGGPRGEKGQKGE--PAII----EPGMLIEGPPGPEGPAGLPGPPG 484

Query: 228 TSSPEVRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGP--------GGGGEEDSPG 279
           T  P  + G   E G        P  R         PG  G         GGGG+    G
Sbjct: 485 TMGPTGQVGDPGERG--------PPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD---AG 533

Query: 280 SASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGC 339
           S  P+ S   S+A     +A  A  L G +GP   T         PG         L+G 
Sbjct: 534 SKGPMVSAQESQAQAILQQARLA--LRGPAGPMGLTGR-------PGPVGPPGSGGLKGE 584

Query: 340 GGDVVQAIEQVLNHHRGGLAAGLGPAAPPDK----AAVGAAAAADDAWPS---RVDAAAA 392
            GDV     +       G+    GPA  P +     + GA        P      D  A 
Sbjct: 585 PGDVGPQGPR-------GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAG 637

Query: 393 AAAAAGGPGLPAPLQAGPAAPP 414
                G  G P P  +GP  PP
Sbjct: 638 LPGEKGHRGDPGP--SGPPGPP 657


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,807,948
Number of Sequences: 37866
Number of extensions: 1820138
Number of successful extensions: 27762
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 376
Number of HSP's successfully gapped in prelim test: 1410
Number of HSP's that attempted gapping in prelim test: 13703
Number of HSP's gapped (non-prelim): 9827
length of query: 542
length of database: 18,247,518
effective HSP length: 107
effective length of query: 435
effective length of database: 14,195,856
effective search space: 6175197360
effective search space used: 6175197360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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