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Search of human proteins with 153792074
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792074 proline rich 12 [Homo sapiens]
(2036 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792074 proline rich 12 [Homo sapiens] 4225 0.0
gi|115647981 glutamine and serine rich 1 [Homo sapiens] 237 1e-61
gi|163965366 nascent polypeptide-associated complex alpha subuni... 146 2e-34
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 142 3e-33
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 137 1e-31
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 133 2e-30
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 130 2e-29
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 130 2e-29
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 130 2e-29
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 127 1e-28
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 122 4e-27
gi|160707881 formin 2 [Homo sapiens] 122 4e-27
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 121 6e-27
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 120 1e-26
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 120 1e-26
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 120 1e-26
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 120 1e-26
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 118 7e-26
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 115 3e-25
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 115 6e-25
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 115 6e-25
gi|48762934 alpha 2 type I collagen [Homo sapiens] 114 7e-25
gi|18079216 CASK interacting protein 1 [Homo sapiens] 113 2e-24
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 112 5e-24
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 111 6e-24
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 110 1e-23
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 109 3e-23
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 109 3e-23
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 108 5e-23
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 108 5e-23
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 4225 bits (10958), Expect = 0.0
Identities = 2036/2036 (100%), Positives = 2036/2036 (100%)
Query: 1 MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYA 60
MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYA
Sbjct: 1 MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYA 60
Query: 61 TNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQT 120
TNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQT
Sbjct: 61 TNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQT 120
Query: 121 AMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPAN 180
AMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPAN
Sbjct: 121 AMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPAN 180
Query: 181 GLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH 240
GLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH
Sbjct: 181 GLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH 240
Query: 241 LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQP 300
LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQP
Sbjct: 241 LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQP 300
Query: 301 PPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG 360
PPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG
Sbjct: 301 PPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG 360
Query: 361 RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSL 420
RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSL
Sbjct: 361 RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSL 420
Query: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480
GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP
Sbjct: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480
Query: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA
Sbjct: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
Query: 541 LSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL 600
LSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL
Sbjct: 541 LSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL 600
Query: 601 APPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADG 660
APPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADG
Sbjct: 601 APPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADG 660
Query: 661 LVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL 720
LVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL
Sbjct: 661 LVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL 720
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG 780
GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG
Sbjct: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG 780
Query: 781 LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840
LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP
Sbjct: 781 LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP 840
Query: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG 900
PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG
Sbjct: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG 900
Query: 901 PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAAD 960
PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAAD
Sbjct: 901 PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAAD 960
Query: 961 DYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPS 1020
DYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPS
Sbjct: 961 DYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPS 1020
Query: 1021 TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080
TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL
Sbjct: 1021 TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080
Query: 1081 LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI 1140
LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI
Sbjct: 1081 LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI 1140
Query: 1141 DFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKP 1200
DFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKP
Sbjct: 1141 DFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKP 1200
Query: 1201 RGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTR 1260
RGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTR
Sbjct: 1201 RGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTR 1260
Query: 1261 EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPAR 1320
EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPAR
Sbjct: 1261 EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPAR 1320
Query: 1321 GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSF 1380
GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSF
Sbjct: 1321 GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSF 1380
Query: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP 1440
Query: 1441 SANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP 1500
SANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP
Sbjct: 1441 SANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP 1500
Query: 1501 LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE 1560
LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE
Sbjct: 1501 LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE 1560
Query: 1561 TDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKD 1620
TDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKD
Sbjct: 1561 TDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKD 1620
Query: 1621 GQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQA 1680
GQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQA
Sbjct: 1621 GQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQA 1680
Query: 1681 KNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740
KNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK
Sbjct: 1681 KNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740
Query: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK 1800
EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK
Sbjct: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK 1800
Query: 1801 WLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVST 1860
WLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVST
Sbjct: 1801 WLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVST 1860
Query: 1861 ALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQ 1920
ALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQ
Sbjct: 1861 ALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQ 1920
Query: 1921 SGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYH 1980
SGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYH
Sbjct: 1921 SGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYH 1980
Query: 1981 TFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG 2036
TFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG
Sbjct: 1981 TFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG 2036
>gi|115647981 glutamine and serine rich 1 [Homo sapiens]
Length = 1735
Score = 237 bits (604), Expect = 1e-61
Identities = 130/300 (43%), Positives = 187/300 (62%), Gaps = 22/300 (7%)
Query: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK 1800
+K + K ++ R ++ + ++S + + P S T A S PK + KVKAEPPPKKRKK
Sbjct: 1444 KKPRNKPSQTIRTVQAKPSSSSKTSDPLASKTTTTKAPSVKPKVKQPKVKAEPPPKKRKK 1503
Query: 1801 WLKEAGGNATAGGGPPGSSSDSESSPG---APSEDERAVPG-----RLLKTRAMREMYRS 1852
W +E SSS S+SSP + S+DE P R L TRAM+E ++S
Sbjct: 1504 WKEEF------------SSSQSDSSPEIHTSSSDDEEFEPPAPFVTRFLNTRAMKETFKS 1551
Query: 1853 YVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHT 1912
Y+E+LVS ALDPD +QALE ++DEL LP M+KIDG+LN+++K++L L L + ++AL +
Sbjct: 1552 YMELLVSIALDPDTMQALEKSNDELLLPHMKKIDGMLNDNRKRLLLNLHLDQSFKNALES 1611
Query: 1913 FPQLQVEQSGEGSPEEGAV--RLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTL 1970
FP+L + + G +++ G+ YN+KTL K + AQEF V+ EK Y+L
Sbjct: 1612 FPELTIITRDSKAKSGGTAISKIKMNGKAYNKKTLRTSKTTTKSAQEFAVDPEKIQLYSL 1671
Query: 1971 YHSLHHYKYHTFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQ 2030
YHSLHHYKYH +L C+D+ +++ EDLGQEE+VQ CM+N W+E LF+ F +LL Q
Sbjct: 1672 YHSLHHYKYHVYLICKDEISSVQKKNEDLGQEEIVQLCMKNVKWVEDLFEKFGELLNHVQ 1731
Score = 196 bits (497), Expect = 3e-49
Identities = 101/175 (57%), Positives = 133/175 (76%), Gaps = 9/175 (5%)
Query: 1549 AKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQK 1608
AK Q+T A+ G TDEE ESGGEG +RERDEFV++ EDI + K AL+TG+EPP IW+VQK
Sbjct: 1329 AKGQDTVAIEGFTDEEDTESGGEGQYRERDEFVVKIEDIETFKEALKTGKEPPAIWKVQK 1388
Query: 1609 ALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWH 1668
ALLQKF PEI+DGQR+F AT++YLGYFGDAK++Y+R+YVKF+EN NKK+YVRVC++KP +
Sbjct: 1389 ALLQKFVPEIRDGQREFAATNSYLGYFGDAKSKYKRIYVKFIENANKKEYVRVCSKKPRN 1448
Query: 1669 RPPVPVRRSGQAKNPVSAGGSSAP------PPKAPAPPPKPETPEKTTSEKPPEQ 1717
+P + R+ QAK P S+ +S P KAP+ PK + P K +E PP++
Sbjct: 1449 KPSQTI-RTVQAK-PSSSSKTSDPLASKTTTTKAPSVKPKVKQP-KVKAEPPPKK 1500
Score = 174 bits (442), Expect = 6e-43
Identities = 158/476 (33%), Positives = 208/476 (43%), Gaps = 63/476 (13%)
Query: 89 MNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSAL 148
MN +S ESR Q S ++LL QFR+PSWQT MH+ TELF +G LP + T P S L
Sbjct: 1 MNFLSTAESRTAQAAASGTTLLPQFRAPSWQTGMHSSAATELFATGPLPSTGTLPPS--L 58
Query: 149 SAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHD-VLHLKPSQAPTVPSSLGFER 207
SAYQHP +F +R F S L LQD F+ +NG+LS HD +L +K SQ TVP++L FER
Sbjct: 59 SAYQHPTTFSNRNFATTSPLVLQDSTFNTTSNGILSHHDPLLQIKTSQG-TVPTALAFER 117
Query: 208 LAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYN 267
L G VL + P Q+ YR P L QF+LL S A Q +PQ Y+
Sbjct: 118 L-GSSVL--SNSIPPQSSTYRSAQES---APHLLQPQFSLLPS----ALGGSQQTPQAYS 167
Query: 268 FSGAAPGPPPPERALPRQDTVIKHYQRPASAQ--PPPPPPPAHALQHYLSCGG--SYPSM 323
+ ERAL R+ +VIKH+QRP+ Q H+L YLS ++
Sbjct: 168 STLFTSSTASIERALLRECSVIKHHQRPSGTQSIQAQLTGSQHSLHSYLSNSSVVNFQET 227
Query: 324 GHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPI 383
+++L+CSP+G G K S Y
Sbjct: 228 TRQSSLSCSPIGDSTQVSNGGLQQKTSQVSVELAQS--------------------YSSA 267
Query: 384 IQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGK----ASGAGGAG 439
I S GY + P ST TPK QS+ P + K S
Sbjct: 268 IPSSGYPPST----TKIKSCSTEQPLTSTKTPKPQSIIPPVQTLSYSKPLHNQSSVISGQ 323
Query: 440 GQAYSPGQPQGLLGPQAYGQGFGGGQAQDL-----SKAPSYSGGPPQPPSGPPPPGLATC 494
Q YS Q LL + Q +G Q ++ S+ S PP +
Sbjct: 324 AQIYSTAQLPSLLS-VSQSQNYGLVQPHNVPSIVHSQVYRSSKVEKLPPLYKTLTFSGSS 382
Query: 495 QSYSPD--------QLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALS 542
Q+ +P+ Q L V E YP A ++ L + S S SYS+GHS LS
Sbjct: 383 QTVTPENQTLNYSSNQQEVLSSVTNENYP---AQTRDLSSVSQSQSYSSGHSQGLS 435
Score = 90.9 bits (224), Expect = 1e-17
Identities = 132/510 (25%), Positives = 200/510 (39%), Gaps = 89/510 (17%)
Query: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAA------DDYGKAGPP 968
S + Q +FV L S+CFP+++L +ER+ ++++ AA D+ K+
Sbjct: 816 SETNQHDSKNQFVSLGSMCFPEAVLLSDERNILSNVDDILAATAAACGVTPTDFSKSTSN 875
Query: 969 E-----DEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPG-LGLDPNKPPELPSTV 1022
E ++GD K+ + A+ P+ L+ N+ TV
Sbjct: 876 ETMQAVEDGDSKSHF--QQSLDVRHVTSDFNSMTATVGKPQNINDTSLNGNQV-----TV 928
Query: 1023 NAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLR 1082
N P+ +QS P P TK + S +
Sbjct: 929 NLSPVPALQSKMTLDQQHIETPGQNIP-----------------TKVTSAVVGPSHEVQE 971
Query: 1083 RRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDF 1142
+ PF KK A E E D ++ P D LN R + VSS RS + + +F
Sbjct: 972 QSSGPF---KKQSATNLESEED---SEAPVDSTLNNNRNQEFVSSSRSISGENATSESEF 1025
Query: 1143 CPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGA----- 1197
G D G R + L + + S +
Sbjct: 1026 ---TLGGDD-------------SGVSMNPARSALALLAMAQSGDAVSVKIEEENQDLMHF 1069
Query: 1198 KKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSS 1257
+ R +G+G+ EE + + +P + K P+ G + S + H D
Sbjct: 1070 NLQKKRAKGKGQVKEEDNSNQKQLKRPAQGKRQNPR-GTDIYLPYTPPSSESCH---DGY 1125
Query: 1258 LTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSV 1317
+EK+ KIKEVEEKQPE+K+GF+ASFLDFLKSG P Q P ++ P
Sbjct: 1126 QHQEKMRQKIKEVEEKQPEVKTGFIASFLDFLKSG----PKQQFSTLAVRMPNRTRRPGT 1181
Query: 1318 P-ARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLET 1376
R P P P+ P P +E+ G SP ++D ELK NLE
Sbjct: 1182 QMVRTFCPPPLPKPSSTTPTPL----------VSETGG-----NSPSDKVDNELK-NLEH 1225
Query: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALD 1406
L SFSSDE+D ++D +S+S+ ++ LD
Sbjct: 1226 LSSFSSDEDDP-GYSQDAYKSVSTPLTTLD 1254
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 146 bits (368), Expect = 2e-34
Identities = 336/1454 (23%), Positives = 473/1454 (32%), Gaps = 275/1454 (18%)
Query: 511 GEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQS 570
GEP P G P +S + S ++ GP S G S +I P +
Sbjct: 596 GEPLP------IGKPASSMTSPLGVNSSASVIKTDSYAGPDS---AGPLLKSSLITPTVA 646
Query: 571 --PPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELL--- 625
P + P GV A G + AS PFL G+ + + K L
Sbjct: 647 AFPLESADPAGVAPTTAKGTSTYTTTAS-PFLE----GTVSLAPKNHPVKEGTLTTLPLV 701
Query: 626 --AGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL--VGEDGAADASKGLGGSGGAG 681
A P A ++ + L+ AP P++ + L G G+ +
Sbjct: 702 PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALA 761
Query: 682 GPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGG----E 737
+P E ED + + +L A + LG+ + K+ P + G +
Sbjct: 762 PVASSPKECPTEDSGA---SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 738 TPEGLATSVVH------------YGAGAKELGAFLQKSPPPPP---PTAQSTQP-TPHGL 781
TP G +S V G+K+ A PP P PT + P +P G+
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878
Query: 782 LLEAGGPDLPLVLPPPPPQLLPSVLS--HAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
L P V+ P P+ P+ + AP+ S ++S PA + G P P P
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK-GIPASPSPK 937
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P PP A S PA PSP+ P PP A PP+P G
Sbjct: 938 GAPTPPA-----ATPPSPKGGPATPSPKWAPT----PPAAT----------PPSPKG-GP 977
Query: 900 GPPNSEGKDPAGAYRSPSPQG---TKAPRFVPLTSICFPDSLLQDEERSFFP-------- 948
P+ +G A PSP+G T +P+ P P S + FP
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 949 -TMEEMFGGGAADDYGKAGPPEDEG---DPKAGAGPP-----PGPPAYDPYGPYCPGRAS 999
T G AA K P PK G P P PPA P P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK------ 1091
Query: 1000 GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPA---PASEPK 1056
GP TP P P P+ P G + + PH+ AP P PP P PK
Sbjct: 1092 -GGPATPS----PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Query: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
G T+P PK L T PP P A + P
Sbjct: 1147 GAPTTPAATPPSPKGGLATP---------PPKGAPTTPAATPPSPKGGLATPS-PKGAPT 1196
Query: 1117 NPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRI 1176
P P + P SP G P P P +G T + + P P P
Sbjct: 1197 TPAATPPSPKGGLATP--SPKG----APTTPAATPPSPKGGLATPSPKGAPTTPAATPP- 1249
Query: 1177 RPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLK----PLKIKLSVP 1232
P P T P A TP A P +G G P K P + P
Sbjct: 1250 SPKGGPATPPPKGAPTPP-AATPPSLKG-----------GLATPPHKGAPNPAVVTPPSP 1297
Query: 1233 KAGEGLGTSSGDAI--SGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLK 1290
K G G + T + S T A + + + K
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 1291 SGKRHPPLYQAGLTPPLSPPK-----SVPPSVPARGLQ-PQP---PATPAVPHPPPSGAF 1341
G P + G TPP + P ++ P P RG P P P +PAV P A
Sbjct: 1358 GGPTTPSSKE-GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416
Query: 1342 GLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSA 1401
E A + G P + +L+ P+ S+ + + ++ +
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPV------SLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 1402 ISALDDPPLAGPKDTSTPDGPPLAPAAAVP-GPPPLPGLPSANSNGTPEPP--------- 1451
P A PK +T P APA P G P LP + ++ P P
Sbjct: 1471 TPPSPKEPPA-PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 1452 ---LLEEKPPPTP-------PPA---PTPQPQPPPPPPPPQPALPSP-----PPLVAPTP 1493
LL +K P T PPA P+P+ P P P PA PS PP V P+
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589
Query: 1494 SSPPPPPLPPPPPPAMPSPPP---PPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAK 1550
P P PPA+ SP P P PPA P +P + PA P+P+ P + P+ +
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP-PSPEKGPATPAPKGT--PTSPPVTPSS 1646
Query: 1551 KQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKAL 1610
+++ + G + +P L + P + V A
Sbjct: 1647 LKDSPTSPASVTCKMGAT------------------VPQASKGLPAKKGPTALKEVLVAP 1688
Query: 1611 LQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRP 1670
+ TP I R+ G + + + K+ + P
Sbjct: 1689 APESTPIITAPTRK-----------GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAP-APP-----------------PKPETPEKTTSE 1712
+PV++ + + G ++ PK P APP PKPE+ + +
Sbjct: 1738 LLPVQKDS---SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAP 1794
Query: 1713 KPPEQTPETAMPEPPAPEKPSLL------------RPVEKEKEKEKVTRGERPLRGERAT 1760
PP P P P P K L +P+ E E + PL
Sbjct: 1795 SPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL-----PLIPPEPI 1849
Query: 1761 SGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSS 1820
SG P +S+ P PT +P K K GS +
Sbjct: 1850 SGGV--PFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK-----------------GSGT 1890
Query: 1821 DSESSPGAPSEDER 1834
+S+S P +E+
Sbjct: 1891 ESDSDESVPELEEQ 1904
Score = 134 bits (338), Expect = 7e-31
Identities = 276/1105 (24%), Positives = 372/1105 (33%), Gaps = 155/1105 (14%)
Query: 34 SSRTSHPETDILHRQAYAAPHPLQSYATNHHP-----------AGLSGLFDTGLHHAGSA 82
SS S E L + + S AT H P + ++ L G+
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
Query: 83 GPDASVMNLISALESRGPQ-PGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSST 141
P SV+NL GP P P + LS S S + A TP P + S + G+ T
Sbjct: 885 TPTPSVVNL--PFPKEGPATPAPKQAPALSM-TSSSPKKARATPAPKGIPASPSPKGAPT 941
Query: 142 FPSSSALSAYQHPASFGSRPFPVPSSLSLQDP---PFSPPANGLLSPHDVLHLKPSQAPT 198
P+++ S PA+ + P P + + P P +P G +P P P
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 199 VPSSLGFERLAGGGVLGPAG------------LGPAQTPPYRPGPPDPPPPPRHLPTQFN 246
PS G P G PA TPP G P P P+ PT
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT--- 1058
Query: 247 LLASSSAAAAAAEQSSPQLYNFSGAAPGP---PPPERALPRQDTVIKHYQRPASAQPPPP 303
+ AA + + P + GA P PP + P + K P +A PP P
Sbjct: 1059 ----TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP-KGAPMPPAATPPSP 1113
Query: 304 P-----PPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGA 358
PP + P G LA P G +P A PS G AT
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGG----LATPPPKGAPTTPAATPPSPKGGL-ATPPP 1168
Query: 359 SGRATGPEAAGGGGAGG------GGGGYRPIIQSPGYKTG---KGGYGAAAGGATRPPPP 409
G T P A GG G P P K G GA A PP P
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228
Query: 410 RS-TATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGL-LGPQAYGQGFGGGQAQ 467
+ ATP P A T A+ GG A P P+G P A GG A
Sbjct: 1229 KGGLATPS------PKGAPTTPAATPPSPKGGPATPP--PKGAPTPPAATPPSLKGGLAT 1280
Query: 468 DLSK-APSYSG-GPPQPPSGP---PPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQ 522
K AP+ + PP P GP PP G T + +P +G + P P A +
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 523 GLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGE--ASPSHIIRPLQSPPATGRPPGV 580
P +P+L +T S GG PSS G A+PSH P +PP+ R P +
Sbjct: 1341 PSPKGTPTLPATTP-----SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395
Query: 581 GSP-GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDE 639
SP G P +V+ +P AP A KGD L P P
Sbjct: 1396 PSPKGDPTS--PAVIPLSPKKAP--ATPVTREGAATPSKGD----LTPPAVTPVS----- 1442
Query: 640 EFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYH 699
L +AP A A KG + + G P P + P+
Sbjct: 1443 ------LKKAP----------------ATSAPKGGPATPSSKGDPTLP-AVTPPSPKEPP 1479
Query: 700 LQSVIRTSASLDEGATAALELGLGRLKEK-KKGPERGGETPEGLATSVVHYGAG-AKELG 757
+ TS+S + +G L P+ TP + +K+
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 758 AFL--QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPP-PPQLLPSVLSHAPSPSP 814
A L +++ PP T S + TP + P P PP + PS APSP
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTP-AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 815 SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL 874
L+ PA +P+ P PP PP P + A G + P ++S
Sbjct: 1599 L-------LIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651
Query: 875 DPPGAMQELLGALEP-----LPPAPGDTGVG----PPNSEGKDPAGAYRSPSPQGTKAPR 925
P ++ +GA P LP G T + P E A PQ K+
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA 1711
Query: 926 FVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDE--------GDPKAG 977
P IC PD ++ + T+ D K +D P++
Sbjct: 1712 TSP--PIC-PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESK 1768
Query: 978 AGPPPGPPAYDPYGPYCPGRASGAGPETP-GLGLDPNKPPELPSTVNAEPL--GLIQSGP 1034
A P A++ P + A P P L L P+ P LP P GL+ P
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828
Query: 1035 HQAAPPPPPPPPPPPAPASEPKGGL 1059
+ P P P GG+
Sbjct: 1829 SKPLAPADEDELLPLIPPEPISGGV 1853
Score = 126 bits (316), Expect = 2e-28
Identities = 341/1478 (23%), Positives = 464/1478 (31%), Gaps = 316/1478 (21%)
Query: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHL--KPS 194
P ++ P ++ + A + P S P PS PP + +G+ + + P
Sbjct: 714 PQNTCAPLATLVLAPEIPKSV-----PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK 768
Query: 195 QAPTVPSSLGFERLAGGGVL----GPAGLGPA-----QTPPYRPGPPDPPPPPRHL---- 241
+ PT S + G + P+ LG + + PP + G P P +L
Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV 828
Query: 242 -PTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP-GPPPPERALPRQDTVIKHYQRPASAQ 299
P + + L +S + ++ S ++ + +P G P P P K P
Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP---KGVTLPPKET 885
Query: 300 PPP-----------PPPPAHALQHYLSCGGSYPSMGHRA----NLACSPLGGGEPSPGAG 344
P P P PA LS S P + SP G P+P A
Sbjct: 886 PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA 945
Query: 345 EPSK-----AGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAA 399
P A PS A AT P GG G P +P + KGG
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP--PSPKGGPATP 1003
Query: 400 AGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQ 459
+ PP + +PK G PAA G + A +P P+G +
Sbjct: 1004 SPKGAPTPPAVTPPSPK----GSPAAT-----PFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 460 GFGGGQAQDLSKAPSYSGGPPQPP-SGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPA 518
G A L PS GGP P G P P AT S P GPA
Sbjct: 1055 GAPTTPAATL---PSPKGGPATPSLKGAPTPPAATPPS----------------PKGGPA 1095
Query: 519 AHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPP 578
S P +P +T SP GG A+P H P +P AT P
Sbjct: 1096 TPS---PKGAPMPPAATPPSPK---------------GGLATPPHKGAPT-TPAATPPSP 1136
Query: 579 GVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTED 638
G P K + A+ P P G A KG + A P P
Sbjct: 1137 KGGLATPPPKGAPTTPAATP---PSPKGGLATPPP----KGAPTTPAATPPSPKGG---- 1185
Query: 639 EEFLIQHLLQAPSP---PRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDP 695
L PSP P T A + G A S + A PP LA P
Sbjct: 1186 --------LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 696 QRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKE 755
+ A AT G P +G TP
Sbjct: 1238 K----------GAPTTPAATPPSPKG-----GPATPPPKGAPTP---------------- 1266
Query: 756 LGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPS 815
P PP+ + TP G P+ P V+ PP P+ P+ +P+P
Sbjct: 1267 --------PAATPPSLKGGLATPP----HKGAPN-PAVVTPPSPKGGPATSPPKGAPTPP 1313
Query: 816 ASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAP--SPRLRPEES 873
A+ P + G+P PPP P PP + P +P +P L P +
Sbjct: 1314 AAT-------PPSPKGSPGTPPPKGAPTPP------------AVTPPSPKGTPTL-PATT 1353
Query: 874 LDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG-TKAPRFVPLTSI 932
G P PPA + G P P PSP+G +P +PL+
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK 1413
Query: 933 CFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGP 992
P + + E G A G PP P P G
Sbjct: 1414 KAPATPVTRE-------------GAATPSKGDLTPP-----AVTPVSLKKAPATSAPKG- 1454
Query: 993 YCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQ-AAPPPPPPPPPPPAP 1051
GP TP DP P P + P P Q A P P PAP
Sbjct: 1455 ---------GPATPSSKGDPTLPAVTPPSPKEPP------APKQVATSSSPKKAPATPAP 1499
Query: 1052 ASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVP 1111
P T P + PK++ T S RRDP T L + A ++ P
Sbjct: 1500 MGAP----TLPAVIPSSPKEVPATPS----SRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 1112 ADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPR 1171
A +P++ P + + + PA +P PP T + G P P+
Sbjct: 1552 AMTVPSPKKTP-AIPTPKEAPA-TPSSKEASSPP------------AVTPSTYKGAPSPK 1597
Query: 1172 GRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSV 1231
L P P+ PT A P +G A + G P+ P +K S
Sbjct: 1598 -----ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDS- 1650
Query: 1232 PKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEV-EEKQPEMKSGFMASFLDFLK 1290
P + + G + L +K +KEV PE +
Sbjct: 1651 PTSPASVTCKMGATVP-----QASKGLPAKKGPTALKEVLVAPAPES--------TPIIT 1697
Query: 1291 SGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAA 1350
+ R P Q + SPP PS P PA P + +A+
Sbjct: 1698 APTRKGP--QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS 1755
Query: 1351 ESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL 1410
S L P S +S + A + L + S+++SA PP+
Sbjct: 1756 HSPKGPLAPPE-----------------SKASTPLTAAAFEKVLPKPESASVSAAPSPPV 1798
Query: 1411 AGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
+ PLAP+ PP LPS+ P L+ E P PA +
Sbjct: 1799 S----------LPLAPSPVPTLPPKQQFLPSS-------PGLVLESPSKPLAPADEDELL 1841
Query: 1471 PPPPPPPPQPALPSPPPLV-APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEE 1529
P PP P +P LV PTP S P P P A P+ +
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTPKS--------------AGIPVPTPSAKQPVTKNNKG 1887
Query: 1530 PAAPSPED---PELPDTRPLHLAKKQETAAVCGETDEE 1564
S D PEL + +Q A E DEE
Sbjct: 1888 SGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEE 1925
Score = 126 bits (316), Expect = 2e-28
Identities = 283/1079 (26%), Positives = 370/1079 (34%), Gaps = 157/1079 (14%)
Query: 80 GSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGS 139
GSAGPD + NL S + P +S L + S S+Q + +P T S P
Sbjct: 813 GSAGPDTPIGNLSSPV-------SPVEASFLPE-NSLSFQGSKDSPATTH---SPTPPSP 861
Query: 140 STFPSSSALSAYQ-HPASFGSRPFPVPSSLSLQDPPFSP--PANGLLSPHDVLHLKPSQA 196
P+ SA++ + + P PS ++L P P PA + P +A
Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921
Query: 197 PTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAA 256
P+ G A G A PA TPP G P P P+ PT AA
Sbjct: 922 RATPAPKGIP--ASPSPKG-APTPPAATPPSPKGGP-ATPSPKWAPT-------PPAATP 970
Query: 257 AAEQSSPQLYNFSGAAPGP---PPPERALPRQDTVIKHYQRPASAQPPPP--PPPAHALQ 311
+ + P + GA P PP + P + K P + PP P P A
Sbjct: 971 PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPKGSPAATPFP 1029
Query: 312 HYLSCGGSYPSMGHRANLACSPLGGGEP-SPGAGEPSKAG----PSGATAGASGRATGPE 366
S + + + A +PL G P +P A PS G PS A AT P
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 367 AAGGGGAGGGGGGYRPIIQSPGYKTGKGGY------GAAAGGATRPPPPR-STATPKCQS 419
GG G P +P + KGG GA A PP P+ ATP
Sbjct: 1090 PKGGPATPSPKGAPMPPAATP--PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP--- 1144
Query: 420 LGGPAAAYATGKASGAGGAGGQAYSPGQPQGL-LGPQAYGQGFGGGQAQDLSKAPSYSGG 478
P A T A+ GG A P P+G P A GG A PS G
Sbjct: 1145 ---PKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLA-----TPSPKGA 1194
Query: 479 PPQPPSGPPPP--GLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTG 536
P P + PP P GLAT SP G P P + GL T SP + +T
Sbjct: 1195 PTTPAATPPSPKGGLAT---PSPK-------GAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 537 HSPALSGHGGGWGPSSLGG--GGEASPSHIIRPLQSPPATGRP-PGVGSPGAPGKYLSSV 593
+ S GG P G A+P + L +PP G P P V +P +P
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP------- 1297
Query: 594 LASAPFLAPPGAGSYAAGAGGYKGKGD-GSELLAGPGGPPAERTEDEEFLIQHLLQAPSP 652
P +PP A KG G+ G PPA + L A +P
Sbjct: 1298 -KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG--TPTLPATTP 1354
Query: 653 PRTSGADGLVGEDGAADASKGLGGSGG-AGGPPGTPYELAKEDPQRYHLQSVIRTSASLD 711
G ++G + GG A PP A P+ + +
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 712 EGATAALELGLGRLKEKKKGPERGGETPEGL---------ATSVVHYG------AGAKEL 756
AT +E P +G TP + ATS G G L
Sbjct: 1415 APATPV-------TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467
Query: 757 GAFLQKSP-PPPPPTAQSTQPTPH---GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSP 812
A SP PP P +T +P G P LP V+P P ++ + S
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 813 SPSA---SKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869
+P+A SK L P P P P P +P EA E ++P P +
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP-PAVT 1586
Query: 870 PEESLDPPGAMQELL--GALEPLP-PAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
P P + L+ P P AP V PP+ E K PA +P+P+GT P
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE-KGPA----TPAPKGT--PTS 1639
Query: 927 VPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGP---------PEDEGDPKAG 977
P+T DS S M + K GP P E P
Sbjct: 1640 PPVTPSSLKDS--PTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 978 AGPPPGP-----PAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032
A GP A P P CP ++ G + P + P P LP ++ +
Sbjct: 1698 APTRKGPQTKKSSATSP--PICPDPSAKNGSKGPLSTVAP--APLLPVQKDSSKTAKGKD 1753
Query: 1033 GPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP 1091
H P P PP + AS P LT+ F K L K S + PP P
Sbjct: 1754 ASHS----PKGPLAPPESKASTP---LTAAAF----EKVLPKPESASVSAAPSPPVSLP 1801
Score = 112 bits (279), Expect = 5e-24
Identities = 284/1183 (24%), Positives = 371/1183 (31%), Gaps = 277/1183 (23%)
Query: 763 SPPPPPPTAQSTQPT-PHGLLLEAGGPDLP-------LVLPPPPPQLLPSVLSHAPSPSP 814
SPP + +PT P L++ P P L +P PP P L + PS
Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523
Query: 815 SASKVGVHLLE-PATRDGAPQPPPPP----PPPPPPMPLQLEAHLRSHGLEPAAPSPR-- 867
L PA+ +GAP P P +PL A S + + SP
Sbjct: 524 VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583
Query: 868 LRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927
L PE +L ++ LG EPLP +G P S P G S S +
Sbjct: 584 LSPEATL-----AKKSLG--EPLP-------IGKPASSMTSPLGVNSSAS--------VI 621
Query: 928 PLTSICFPDSLLQDEERSFF-PTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPP--GP 984
S PDS + S PT+ A P + DP AG P G
Sbjct: 622 KTDSYAGPDSAGPLLKSSLITPTV--------------AAFPLESADP-AGVAPTTAKGT 666
Query: 985 PAYDPYG-PYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP 1043
Y P+ G S L P P T+ PL S AP P
Sbjct: 667 STYTTTASPFLEGTVS----------LAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQN 716
Query: 1044 PPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP---KKLYAQEYE 1100
P L + + PK + S PP TP KK+ +
Sbjct: 717 TCAP-----------LATLVLAPEIPKSVPSPSL--------PPAGTPPGTKKVDGISH- 756
Query: 1101 FEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDG----PRRRG 1156
A + +P+ P S + S G + + +P P G P+ +
Sbjct: 757 -------TSALAPVASSPKECPTEDSGASA--TASSKGTLTYLADSPSPLGVSVSPQTK- 806
Query: 1157 RKPTKAKRDGPPRPRGR--PRIRPLEVP-----------TTAGPASASTPTDGAKKPRGR 1203
R PTK GP P G + P+E + PA+ +PT + P+G
Sbjct: 807 RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS--PKGA 864
Query: 1204 GRGRGRKAEEAGGTRLEPLK---PLKIKLSVPKAGEGL-GTSSGDAISGTDHNSLDSSLT 1259
G L P + P + L PK G A+S T + + T
Sbjct: 865 PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARAT 924
Query: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVP--PSV 1317
P K G AS P + TPP + P S P+
Sbjct: 925 ---------------PAPK-GIPAS------------PSPKGAPTPPAATPPSPKGGPAT 956
Query: 1318 PARGLQPQPPA-TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLET 1376
P+ P PPA TP P P+ G A + PSP + T
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP------PSPKGGPATPSPKGAPT 1010
Query: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPL 1436
P+ + + S+ +A P P T P G P PAA +P P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 1437 PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP---------------------- 1474
P PS G P PP P P P+P+ P PP
Sbjct: 1071 PATPSLK--GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 1475 ----PPPPQPALPSPPPLVAPT-PSSPPPPP---LPPPPPPAMPSPPPPPPPA------- 1519
PP P+ L +PPP APT P++ PP P L PPP P+ P PP+
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 1520 -------AAPLAAPPEEP---AAPSPED-PELPDTRPLH----LAKKQETAAVCGETDEE 1564
P A PP A PSP+ P P P LA A
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 1565 AGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQ 1624
GG + A PSLK L T PP A++ +P K G
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLAT---PPHKGAPNPAVVTPPSP--KGGP-- 1301
Query: 1625 FCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPV 1684
ATS G P PP P G P
Sbjct: 1302 --ATSPPKG----------------------------APTPPAATPPSP---KGSPGTPP 1328
Query: 1685 SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAM-PEPPAPEK-----PSLLRPV 1738
G + P P+P P P T S K TP + P PPA P++ P
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Query: 1739 EKEKEKEKVTRGER------PLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAE 1792
K +G+ PL ++A + TR AT P P +K
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 1793 PPPKKRKKWLKEAGGNAT--AGGGP--PGSSSDSESSPGAPSE 1831
P K GG AT + G P P + S P AP +
Sbjct: 1447 PATSAPK------GGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483
Score = 48.1 bits (113), Expect = 9e-05
Identities = 131/576 (22%), Positives = 188/576 (32%), Gaps = 110/576 (19%)
Query: 1300 QAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGC 1359
QAGLT P +V P V Q P +P+ S L A+ LG
Sbjct: 548 QAGLTTKKDP--TVLPLV-----QAAPKNSPSFQSTSSSPEIPLSPEATLAKKS---LGE 597
Query: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
P P + + L S S + DS A + S++ + A P +++ P
Sbjct: 598 PLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSL--ITPTVAAFPLESADP 655
Query: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGT----PEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475
G +AP A G S GT P+ ++E T P PT P P
Sbjct: 656 AG--VAPTTA-KGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAP 712
Query: 1476 PPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPP-------AMPSPPPPPPPAAAPLAAPP 1527
P P ++AP P S P P LPP P + P A++P P
Sbjct: 713 SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPT 772
Query: 1528 EEPAAPSPEDPE-----LPDT-RPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFV 1581
E+ A + + L D+ PL ++ +T + G +G + V
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPV 828
Query: 1582 --IRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAK 1639
+ A +P L+ Q ++ P A TP G A +
Sbjct: 829 SPVEASFLPENSLSFQGSKDSP-------ATTHSPTPPSPKGAPTPSAVTP--------- 872
Query: 1640 NRYQRLYVKFLENVNKKDYVRVCARKPWHR--PPVPVRRSGQAKNPVSAGGSSAPPPKAP 1697
L K + K+ P+ + P P + A + S+ A P
Sbjct: 873 -----LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA--TP 925
Query: 1698 APPPKPETPEKTTSEKPPEQTPETAM-----------PEPPAPEKPSLLRPVEKEKEKEK 1746
AP P +P + PP TP + P PPA PS
Sbjct: 926 APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS------------- 972
Query: 1747 VTRGERPLRGERATSGRQTRPERSLAT-----GQPATSRLPKARPTKVKAEPPPKKRKKW 1801
+G AT + P AT G PAT PK PT PP K
Sbjct: 973 -------PKGGPATPSPKGAPTPPAATPPSPKGGPATPS-PKGAPTPPAVTPPSPK---- 1020
Query: 1802 LKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVP 1837
G+ A P G+S+ ++P +P A P
Sbjct: 1021 -----GSPAATPFPKGASTPPAATPPSPKGSPAATP 1051
Score = 48.1 bits (113), Expect = 9e-05
Identities = 46/179 (25%), Positives = 57/179 (31%), Gaps = 18/179 (10%)
Query: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE 1725
P PP P + A P+ G + P P+P P TP + PP TP +
Sbjct: 1036 PAATPPSP--KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093
Query: 1726 PPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERAT-SGRQTRPERSLAT----GQPATSR 1780
P P P K P +G T + P+ LAT G P T
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 1781 LPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSD--SESSPGAPSEDERAVP 1837
P A PPPK G T PP + S GAP+ P
Sbjct: 1154 ATPPSPKGGLATPPPK---------GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Score = 47.4 bits (111), Expect = 1e-04
Identities = 60/189 (31%), Positives = 69/189 (36%), Gaps = 35/189 (18%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPK-AP----APPPKPETPEKTTSEKPPEQTPETAMP 1724
PP + A P GG + PPPK AP A PP P+ T S P+ P T
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAA 1200
Query: 1725 EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLAT-----GQPATS 1779
PP+P K L P K P +G AT + P AT G PAT
Sbjct: 1201 TPPSP-KGGLATPSPKGAPTTPAATPPSP-KGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 1780 RLPKARPTKVKAEPPPKKRKKWLKEAGGNAT---------AGGGPPGSSSDSESSP--GA 1828
PK PT A PP K GG AT A PP +SP GA
Sbjct: 1259 P-PKGAPTPPAATPPSLK--------GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 1829 PSEDERAVP 1837
P+ P
Sbjct: 1310 PTPPAATPP 1318
Score = 47.0 bits (110), Expect = 2e-04
Identities = 58/206 (28%), Positives = 70/206 (33%), Gaps = 39/206 (18%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPK-AP----APPPKPETPEKTTSEKPPEQTPETAMP 1724
PP + A P GG + P PK AP A PP P+ T S K TP P
Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Query: 1725 EPP----------APEKPSLLRPVEKEKEKEKVTRG--------ERPLRGERATSGRQTR 1766
P AP P+ P K +G L+G AT +
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
Query: 1767 PERSLAT-----GQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNAT--------AGG 1813
P ++ T G PATS PK PT A PP K G T G
Sbjct: 1287 PNPAVVTPPSPKGGPATSP-PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Query: 1814 GP--PGSSSDSESSPGAPSEDERAVP 1837
P P ++ S+ P PS E P
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTP 1371
Score = 46.6 bits (109), Expect = 2e-04
Identities = 49/177 (27%), Positives = 60/177 (33%), Gaps = 20/177 (11%)
Query: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE 1725
P PP P G P G + P P+P P TP + PP TP +
Sbjct: 1221 PAATPPSP---KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL--- 1274
Query: 1726 PPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLAT-----GQPATSR 1780
K L P K V P +G ATS + P AT G P T
Sbjct: 1275 -----KGGLATPPHKGAPNPAVVTPPSP-KGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 1781 LPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVP 1837
PK PT PP K L ++ GGP SS +P A + + P
Sbjct: 1329 -PKGAPTPPAVTPPSPKGTPTLPAT--TPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Score = 43.5 bits (101), Expect = 0.002
Identities = 50/171 (29%), Positives = 59/171 (34%), Gaps = 17/171 (9%)
Query: 1680 AKNPVSAGGSSAPPPK-APAPP----PKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSL 1734
A P GG + P PK AP PP P P+ T TP A PP+P+
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA--TPPSPKGSPA 1048
Query: 1735 LRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLAT-----GQPATSRLPKARPTKV 1789
P+ K P +G AT + P AT G PAT PK P
Sbjct: 1049 ATPLPKGAPTTPAATLPSP-KGGPATPSLKGAPTPPAATPPSPKGGPATPS-PKGAPMPP 1106
Query: 1790 KAEPP-PKKRKKWLKEAGGNATAGGGPPGSSSDSESSP--GAPSEDERAVP 1837
A PP PK G T PP + P GAP+ P
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Score = 42.0 bits (97), Expect = 0.006
Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 11/121 (9%)
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
P A P L + G P P L PP +P P P P P P+ +
Sbjct: 19 PQAETAVLPMSSALSVTAALGQPGPTL---PPPCSPAPQQCPLSAANQASPFPSPSTIAS 75
Query: 1486 PPLVAPTPSSPPPPPLP----PPPPPAMPS-PPPPPPPAAAPLAAP---PEEPAAPSPED 1537
PL P P S LP P P +P+ PP PAA LA+P P PS
Sbjct: 76 TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSA 135
Query: 1538 P 1538
P
Sbjct: 136 P 136
Score = 41.2 bits (95), Expect = 0.010
Identities = 48/171 (28%), Positives = 69/171 (40%), Gaps = 25/171 (14%)
Query: 756 LGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPS 815
L A Q SP P P T ST P + G LPL P P LP+++ P SP+
Sbjct: 58 LSAANQASPFPSPSTIAST-PLEVPFPQSSSGTALPLGTAPEAPTFLPNLI--GPPISPA 114
Query: 816 ASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
A + ++ P + P PL L A L H ++ ++ P P
Sbjct: 115 ALALASPMIAPTLKG----------TPSSSAPLALVA-LAPHSVQKSSAFP---PNLLTS 160
Query: 876 PPGAMQELLGALEPL--PPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAP 924
PP G++ L P AP + P + K P+ P+P+GT +P
Sbjct: 161 PPSVAVAESGSVITLSAPIAPSE----PKTNLNKVPSEVV--PNPKGTPSP 205
Score = 40.4 bits (93), Expect = 0.018
Identities = 74/304 (24%), Positives = 98/304 (32%), Gaps = 58/304 (19%)
Query: 1310 PKSVPPSVPARGLQ-PQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDE 1368
P +VPA + PQP A AV P S A + AL G P PC +
Sbjct: 2 PGEATETVPATEQELPQPQAETAVL--PMSSALSVTAALGQP-----GPTLPPPCSPAPQ 54
Query: 1369 E--LKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP 1426
+ L + P S S +S S L P A P GPP++P
Sbjct: 55 QCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEA-PTFLPNLIGPPISP 113
Query: 1427 AA-AVPGPPPLPGLPSANSNGTPEP-----PLLEEKPPPTPPPAPTPQPQ---------- 1470
AA A+ P P L S+ P P +K PP T P
Sbjct: 114 AALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173
Query: 1471 ---PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP------------AMPSPPPP 1515
P P P+ L P V P P P PP P + S P
Sbjct: 174 TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQT 233
Query: 1516 PPPAAAPLAAP-------------PEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETD 1562
P +A+P P+ P + S + P P P L+ ++ V +
Sbjct: 234 TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSP---PAALSLSTQSLPVVTSSQ 290
Query: 1563 EEAG 1566
+ AG
Sbjct: 291 KTAG 294
Score = 40.4 bits (93), Expect = 0.018
Identities = 71/330 (21%), Positives = 113/330 (34%), Gaps = 22/330 (6%)
Query: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLG----LG 1358
L P+SPP ++ S + + T A P+ PP LG L G LG
Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQKT-AGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG 324
Query: 1359 CPSPCKRLDEELKR-------NLETLPSFSSDEEDSVAKNRDLQESISS---AISALDDP 1408
P D +K + PS S ++N + ++++ ++D
Sbjct: 325 QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKG 384
Query: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
P T +P G L A + P + ++ N T PL+ + P + P
Sbjct: 385 PSTISSITCSPSGS-LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVV 443
Query: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM---PSPPPPPPPAAAPLAA 1525
P P V+P SS P + P P A+ P P P A
Sbjct: 444 TNPCTIAAAPTTTF-EVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLR 502
Query: 1526 PPEEPAAPSPED-PELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVI-R 1583
P P P PED LP + + +++ V + G+ ++D V+
Sbjct: 503 IPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPL 562
Query: 1584 AEDIPSLKLALQTGREPPPIWRVQKALLQK 1613
+ P + Q+ P I +A L K
Sbjct: 563 VQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592
Score = 39.3 bits (90), Expect = 0.040
Identities = 46/179 (25%), Positives = 55/179 (30%), Gaps = 25/179 (13%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP-A 1728
PP P + A P G S+ P A PP +P T K TP +P P
Sbjct: 1016 PPSP--KGSPAATPFPKGASTPP---AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 1729 PEKPSL----LRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLAT----GQPATSR 1780
P PSL P + P + P+ LAT G P T
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 1781 LPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSP--GAPSEDERAVP 1837
P A PPPK G T PP + P GAP+ P
Sbjct: 1131 ATPPSPKGGLATPPPK---------GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Score = 36.6 bits (83), Expect = 0.26
Identities = 44/170 (25%), Positives = 64/170 (37%), Gaps = 14/170 (8%)
Query: 750 GAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP--PPPQLLPSVLS 807
G + + A Q+ P P TA + + G P P + PP P PQ P +
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG-PTLPPPCSPAPQQCPLSAA 61
Query: 808 HAPSPSPSASKVGVHLLE---PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAP 864
+ SP PS S + LE P + G P P P +P + + L A+P
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 865 --SPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGA 912
+P L+ S P A+ L P + + PPN P+ A
Sbjct: 122 MIAPTLKGTPSSSAPLALVAL------APHSVQKSSAFPPNLLTSPPSVA 165
Score = 34.7 bits (78), Expect = 0.98
Identities = 65/293 (22%), Positives = 97/293 (33%), Gaps = 46/293 (15%)
Query: 1306 PLSPPKSVPPSVPARGLQPQPPATPA------------VPHPPPS--------------- 1338
P+S SV ++ G PP +PA P P PS
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 1339 --GAFGLGGALEAAESEGLGLG---CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRD 1393
A LG A EA +G P+ + L+ PS S+
Sbjct: 87 SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146
Query: 1394 LQESISSAISALDDPPLAGPKDTST--PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPP 1451
+Q+S + + L PP ++ + P+AP+ +P N GTP PP
Sbjct: 147 VQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
Query: 1452 LLEEKPP--PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAM 1509
+ P P A P P L P V T S + P P ++
Sbjct: 207 CIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTIS--SVLISPQNPGSL 264
Query: 1510 PSPPPPPPPAA-------APLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555
P PPAA P+ ++ A P+ P+ P + HLA +++
Sbjct: 265 SLKGPVSPPAALSLSTQSLPVVTSSQKTAGPN-TPPDFPISLGSHLAPLHQSS 316
Score = 34.7 bits (78), Expect = 0.98
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 7/120 (5%)
Query: 84 PDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFP 143
P +S +++ +AL GP P S Q + A P P+ + + P FP
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI---ASTPLEVPFP 83
Query: 144 SSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSL 203
SS+ +A G+ P +L PP SP A L SP LK + + + P +L
Sbjct: 84 QSSSGTALP----LGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLAL 139
Score = 34.7 bits (78), Expect = 0.98
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 14/62 (22%)
Query: 1688 GSSAPPPKAPAPP-------------PKPETPEKTTSEKP-PEQTPETAMPEPPAPEKPS 1733
G + PPP +PAP P P T T E P P+ + TA+P APE P+
Sbjct: 42 GPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPT 101
Query: 1734 LL 1735
L
Sbjct: 102 FL 103
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 142 bits (359), Expect = 3e-33
Identities = 270/1063 (25%), Positives = 359/1063 (33%), Gaps = 202/1063 (19%)
Query: 120 TAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPA 179
+A +PGP L G F + S+ + + S + P F PP
Sbjct: 834 SASESPGPGGLASLGKHRPKGFFATESSFDPHHR------------AQPSYERPSFLPPG 881
Query: 180 NGLLSPHDVLHLKPSQAPTV-PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
GL+ + P + P ++ F R V G + PP PP+PP
Sbjct: 882 PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLS--VPGSEDI----PPPPTTSPPEPPYST 935
Query: 239 RHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAA-PGPPPPERALPRQDTVIKHYQR--P 295
+P+ L S S L S A+ GP PP+ + ++ + H P
Sbjct: 936 PPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPP 995
Query: 296 ASAQPP-------PPPPPAHALQH-----YLSCGGSYPSMGHRANLACSPL------GGG 337
A PP PPP P H H + GGS R L P GG
Sbjct: 996 AHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGP 1055
Query: 338 EPSPGAGEPSKAGPSGATAGAS-GRA-----TGPEAAGGG---GAGGGGGGYRPIIQSPG 388
P+PGA PS G +G G+S G A P AA A G G P+++
Sbjct: 1056 SPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTK 1115
Query: 389 Y--KTGKGGYGAAAGGATRP----PPPRSTATPKCQSLGGPAAAYATGKASGAG----GA 438
+ KGG A T P PPP A + S+ P S +G G+
Sbjct: 1116 VEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGS 1175
Query: 439 GGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYS 498
+A P QP+ G GGG S AP+ S PP P
Sbjct: 1176 STEAEPPTQPE--------PTGGGGGGGSSPSPAPAMSPVPPSP---------------- 1211
Query: 499 PDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSG---HGGGWGPSSLGG 555
P P PA+ P+ +L +++ AL G GGW +
Sbjct: 1212 -------------SPVPTPAS-----PSGPATLDFTSQFGAALVGAARREGGWQNEA--- 1250
Query: 556 GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYL--SSVLASAPFLAPPGAGSYAAGAG 613
S + + G G+G+ APG L S + F A P +AG+G
Sbjct: 1251 ---RRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSG 1307
Query: 614 -GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLL--QAPSPPRTSGADGLVGEDGAADA 670
GY G G GS G GG A + + H L +A P G E ++
Sbjct: 1308 AGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKES 1367
Query: 671 SKGLGGSGGAGGPPGTPYELAKEDPQRY----HLQSVIRT-SASLDEGATAALELGLGRL 725
S+G G PP YE P + H + V+R AS + A L G
Sbjct: 1368 SEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLG 1427
Query: 726 KEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPP-------TAQSTQP-- 776
++K P L + G L L PP P P +A +P
Sbjct: 1428 SQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPER 1487
Query: 777 -----------TPHGLLLEAGGP---DLPLVLPPPPPQLLPSVLSHAPSP-SPSASKV-G 820
P + GP D P V PP P + +P PSP SP AS+ G
Sbjct: 1488 LPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVP------PSPTSPRASEENG 1541
Query: 821 VHLL---EPA----TRDG-----APQPPP-----------PPPPPPPPMPLQLEAHLRSH 857
+ LL PA DG P PPP P P PP PL + +
Sbjct: 1542 LPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP-DTPAPAT 1600
Query: 858 GLEPAAPSPRLRPEESLDPPGAM-----QELLGALEPLPPAPGDT-GVGPPNSEGKDPAG 911
L P P +LD + E+ + APGD GPP PA
Sbjct: 1601 PLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAA 1660
Query: 912 AYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDE 971
P P + S D L+ + + GGG+A
Sbjct: 1661 PQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG----------- 1709
Query: 972 GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL--PSTVNAEPLGL 1029
G AGAG GP D Y Y G+A G G TPG P PP+L PS + LG
Sbjct: 1710 GGGGAGAGVASGPELLDTYVAYLDGQAFG-GSSTPG----PPYPPQLMTPSKLRGRALGA 1764
Query: 1030 ---IQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
++ GP P P P + GL + CS P
Sbjct: 1765 SGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPP 1807
Score = 85.9 bits (211), Expect = 4e-16
Identities = 194/832 (23%), Positives = 255/832 (30%), Gaps = 190/832 (22%)
Query: 791 PLVLPPPPPQLLPSVLSHA-----PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP-- 843
P LPP P +L A P +P A K L P + D P P PP PP
Sbjct: 875 PSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYS 934
Query: 844 -PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLP---------PA 893
PP+P S G PSPR P +P G+ PLP P+
Sbjct: 935 TPPVP-------SSSGR--LTPSPRGGP---FNP--------GSGGPLPASSPASFDGPS 974
Query: 894 PGDTGVGPPNSE----GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPT 949
P DT VG G P + P AP P P P
Sbjct: 975 PPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP------------PH 1022
Query: 950 MEEMFGGGAADDYGKA---GP-PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPET 1005
EM GG+ DD GP P G G P PG P+ +G G S GP
Sbjct: 1023 PPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082
Query: 1006 PGLGLDPNKP------PELPSTVNAEPL---GLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
L P P PL ++ P + PP P P PA P
Sbjct: 1083 RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP- 1141
Query: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
P P ++++ +P I
Sbjct: 1142 -----------------------------PAVAAP-----------SEKNSIPIPTIII- 1160
Query: 1117 NPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRI 1176
+ P SS RS S + P G G P A PP P
Sbjct: 1161 ---KAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPS----- 1212
Query: 1177 RPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGE 1236
VPT A P+ +T ++ G A GG + E + + LS E
Sbjct: 1213 ---PVPTPASPSGPATLDFTSQF----GAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265
Query: 1237 -----GLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEE----------KQPEMKSGF 1281
GLGT + S+D + + +++ + G
Sbjct: 1266 DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
Query: 1282 MASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQ--------PQPPATPAVP 1333
++F FL PL L P + P + + R L+ PQPP P P
Sbjct: 1326 SSAFTSFLPPRPLVHPLTGKALDP--ASPLGLALAARERALKESSEGGGAPQPPPRPPSP 1383
Query: 1334 H---PPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAK 1390
PPP+ A G P P +R L S E+ A
Sbjct: 1384 RYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARR-------ELGYRAGLGSQEKSLPAS 1436
Query: 1391 NRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEP 1450
+ S+ + PP A P PL P P PG+ + PE
Sbjct: 1437 PPAARRSLLHRL-----PPTA-------PGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEE 1484
Query: 1451 P--------LLEEKPPPTPPPA---PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
P LE P P + P + P PPP P+ ++P P + + P
Sbjct: 1485 PERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPL 1544
Query: 1500 PLPPPPPPAMP--------SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543
+ PPP P++ P PPP + PE P P P P LPDT
Sbjct: 1545 LVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP-LPDT 1595
Score = 82.0 bits (201), Expect = 5e-15
Identities = 293/1219 (24%), Positives = 384/1219 (31%), Gaps = 319/1219 (26%)
Query: 424 AAAYATGKASGAGGAGGQA-YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQP 482
AAA T AS + G GG A +P+G ++ Q PSY +P
Sbjct: 827 AAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQ-------PSYE----RP 875
Query: 483 PSGPPPPGLATCQSYSPDQLQGQLYGVQGE--PYPGPAAH----------SQGLP----T 526
PP PGL L+ + G + PY P A S+ +P T
Sbjct: 876 SFLPPGPGL---------MLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTT 926
Query: 527 ASPSLSYSTGHSPALSGH------GGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV 580
+ P YST P+ SG GG + P S G +SP+ P SPP T V
Sbjct: 927 SPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGP--SPPDTR----V 980
Query: 581 GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDE- 639
GS Y S L A P +A + A P PP T
Sbjct: 981 GSR-EKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHH-------AHPPHPPEMETGGSP 1032
Query: 640 EFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYH 699
+ L P P G A + G +GG GG P RY
Sbjct: 1033 DDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP-------ALRYF 1085
Query: 700 LQSVIRTSASLDEGATAALELGLGRL-----KEKKKG-PERGGETPEGLATSVVHYGAGA 753
SA++ A + G GR + K +G P++GG P + +
Sbjct: 1086 QLPPRAASAAMYVPARS----GRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP 1141
Query: 754 KELGAFLQKSPPPPP------PTAQSTQPTPHGLLLEAGGPDLPLVL---------PPPP 798
+ A +K+ P P P+ S+ + G EA P P P P
Sbjct: 1142 PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPA 1201
Query: 799 PQLLPSVLSHAPSPSPSA----------SKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848
P + P S +P P+P++ S+ G L+ A R+G Q + L
Sbjct: 1202 PAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRST---LFL 1258
Query: 849 QLEAHLRSHGL----EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
+A G AAP PRLR +S+D E LE G G G +
Sbjct: 1259 STDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSR 1318
Query: 905 E--GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS-----LLQDEERSFFPTMEEMFGGG 957
G + A+ S P P PLT + L ER+ + E GGG
Sbjct: 1319 AYGGGGGSSAFTSFLPP---RPLVHPLTGKALDPASPLGLALAARERALKESSE---GGG 1372
Query: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPG-RASGAGPETP---------G 1007
A PP P+ A PPP P + P+ + P R GA P P G
Sbjct: 1373 APQ------PPPRPPSPRYEA-PPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAG 1425
Query: 1008 LGLD----PNKPP--------ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
LG P PP LP T L+Q G AP P P A EP
Sbjct: 1426 LGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEP 1485
Query: 1056 KGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR 1115
+ F + TS R PP ED VP
Sbjct: 1486 ERLPLHVRFLENCQPRAPVTSG------RGPP----------------SEDGPGVPPP-- 1521
Query: 1116 LNPRR-LPDLVSSCRSR----------PALSPLGDID-----FCPPNPGPDGPRRRGRKP 1159
+PRR +P +S R+ P +P D++ F P P P KP
Sbjct: 1522 -SPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
Query: 1160 TKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRL 1219
GPP P +P T PA T L
Sbjct: 1581 ESPLTPGPPHP----------LPDTPAPA----------------------------TPL 1602
Query: 1220 EPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKS 1279
P+ P + + P T A S T ++S ++LT+ A
Sbjct: 1603 PPVPPPAVAAAPP-------TLDSTASSLTSYDSEVATLTQGASAAP------------- 1642
Query: 1280 GFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSG 1339
G HPP PP P+ PA PA P P P
Sbjct: 1643 ------------GDPHPP----------GPPA---PAAPA----------PAAPQPGPDP 1667
Query: 1340 AFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESIS 1399
G +E +S P + + + TL S S++ S ++
Sbjct: 1668 PPGTDSGIEEVDSRS---SSDHPLETIS-----SASTLSSLSAEGGGSAGGGGGAGAGVA 1719
Query: 1400 SAISALD------DPPLAGPKDTSTPDGPPL-------------APAAAVPGP------P 1434
S LD D G T P PP A PGP P
Sbjct: 1720 SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDP 1779
Query: 1435 PLPGLPSANSNGTPEPPLLEEKP---PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491
P P+ + G LL + PPT A P P PP P P S P + P
Sbjct: 1780 VTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839
Query: 1492 TPSSPPPPPLPPPPPPAMP 1510
P PPP P P P A P
Sbjct: 1840 WEEGPGPPPPPLPGPLAQP 1858
Score = 77.8 bits (190), Expect = 1e-13
Identities = 129/523 (24%), Positives = 170/523 (32%), Gaps = 98/523 (18%)
Query: 82 AGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGA------ 135
A P A+ +L+ L P GP L ++ +P PG ++ + S A
Sbjct: 1435 ASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPH-------PGVSKPWRSAAPEEPER 1487
Query: 136 LPGSSTF-----PSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPA---NGL----- 182
LP F P + S P+ G P S+ P SP A NGL
Sbjct: 1488 LPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVL 1547
Query: 183 --------LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDP 234
+ + L ++P P + S FE+ GP P P P PP P
Sbjct: 1548 PPPAPSVDVEDGEFLFVEPLPPP-LEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVP 1606
Query: 235 PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP----PPERALPRQDTVIK 290
PP P L S++++ + + L + AAPG P PP A P
Sbjct: 1607 PPAVAAAPP---TLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAP------- 1656
Query: 291 HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG 350
PA+ QP P PPP G S +
Sbjct: 1657 ---APAAPQPGPDPPP----------------------------GTDSGIEEVDSRSSSD 1685
Query: 351 PSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY--GAAAGGATRPPP 408
T ++ + A GGG AGGGGG + P Y G A GG++ P P
Sbjct: 1686 HPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGP 1745
Query: 409 PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQD 468
P L G A + G G G +P P G G G A
Sbjct: 1746 PYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPT----VSVTGAGTDGLLALR 1801
Query: 469 LSKAP---SYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQL-YGVQGEPYPGPAAHSQGL 524
P +GGP PP L T S L + G P PGP A Q
Sbjct: 1802 ACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQAS 1861
Query: 525 PTASPSLSYSTGHSPALSGHGGG--------WGPSSLGGGGEA 559
A+ S + S L GG W GGGG++
Sbjct: 1862 ALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDS 1904
Score = 68.9 bits (167), Expect = 5e-11
Identities = 90/316 (28%), Positives = 110/316 (34%), Gaps = 96/316 (30%)
Query: 1296 PPLYQAGLTPPLSPP------KSVPPSVPAR---------GLQPQPPATPAVPHPPPSGA 1340
P L Q G PP P +S P P R QP+ P T PPS
Sbjct: 1457 PLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSG--RGPPS-- 1512
Query: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
+G G+ PSP +R++ P+ E++
Sbjct: 1513 -----------EDGPGVPPPSP--------RRSVPPSPTSPRASEEN------------- 1540
Query: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPT 1460
+ L PP A D DG L P PPPL +NS PE PL P P
Sbjct: 1541 GLPLLVLPPPAPSVDVE--DGEFLF---VEPLPPPLE---FSNSFEKPESPLTPGPPHPL 1592
Query: 1461 PPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS-----------------------PP 1497
P TP P P PP PP PA+ + PP + T SS PP
Sbjct: 1593 PD---TPAPATPLPPVPP-PAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648
Query: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQET-AA 1556
PP P P PA P P P PPP + EE + S D PL T ++
Sbjct: 1649 GPPAPAAPAPAAPQPGPDPPPGT---DSGIEEVDSRSSSD------HPLETISSASTLSS 1699
Query: 1557 VCGETDEEAGESGGEG 1572
+ E AG GG G
Sbjct: 1700 LSAEGGGSAGGGGGAG 1715
Score = 66.6 bits (161), Expect = 2e-10
Identities = 150/611 (24%), Positives = 203/611 (33%), Gaps = 150/611 (24%)
Query: 1295 HPPLYQAGLTPPLSPPK-SVPPSVPARGLQPQPPA-TPAVPHPPPSGAFGLGGALEAAES 1352
HPP + G +P PP+ ++ P RG + P+ TP P P G+ G GG S
Sbjct: 1022 HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGG----SS 1077
Query: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKN-RDLQESISSAISALDDPPLA 1411
+G L R + P +S A++ R + + +P
Sbjct: 1078 QGPAL--------------RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKG 1123
Query: 1412 GPKDTSTPDGP-PLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
G P P P +PA+ P PPP PS N P P ++ K P T + Q
Sbjct: 1124 G----GLPPAPSPTSPAS--PQPPPAVAAPS-EKNSIPIPTIII-KAPSTSSSGRSSQGS 1175
Query: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEP 1530
PP QP P SSP P P P PP+ PSP P P + P
Sbjct: 1176 STEAEPPTQP---EPTGGGGGGGSSPSPAPAMSPVPPS-PSPVPTPASPSGPATLDFTSQ 1231
Query: 1531 AAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSL 1590
+ + + A+++ T + + +E G GG G
Sbjct: 1232 FGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLG------------------ 1273
Query: 1591 KLALQTGREPPPIWRVQKALLQ-KFTPEIKDGQRQFCATSNYLGYFGDAKNRY-----QR 1644
TG P P R K++ + F+ E + + Y GY G Y
Sbjct: 1274 -----TGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGY-GAGSRAYGGGGGSS 1327
Query: 1645 LYVKFLENVNKKDYVRVCARKPWHRPPVPVRR--SGQAKNPVSAGG-----------SSA 1691
+ FL PP P+ +G+A +P S G S+
Sbjct: 1328 AFTSFL-------------------PPRPLVHPLTGKALDPASPLGLALAARERALKESS 1368
Query: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE 1751
AP PPP+P +P E PP P P + PV +
Sbjct: 1369 EGGGAPQPPPRPPSPR---YEAPP--------PTPHHHSPHAHHEPVLRLWGASPPDPAR 1417
Query: 1752 RPLRGERATSGRQTRPERSLATGQPAT-----SRLPKARP------TKVKAEPP---PKK 1797
R L G RA G Q E+SL PA RLP P ++ EPP P
Sbjct: 1418 REL-GYRAGLGSQ---EKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGV 1473
Query: 1798 RKKWLKEA-------------------GGNATAGGGPPGSSSDSESSPGA-PSEDERAVP 1837
K W A T+G GPP SE PG P R+VP
Sbjct: 1474 SKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPP-----SEDGPGVPPPSPRRSVP 1528
Query: 1838 GRLLKTRAMRE 1848
RA E
Sbjct: 1529 PSPTSPRASEE 1539
Score = 58.5 bits (140), Expect = 6e-08
Identities = 272/1213 (22%), Positives = 363/1213 (29%), Gaps = 266/1213 (21%)
Query: 9 GFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGL 68
G G PL A + S++ + GS S + L + PH +A P
Sbjct: 957 GSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQP--- 1013
Query: 69 SGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPT 128
HH + P M + + P+ L +R P P+
Sbjct: 1014 --------HHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS 1065
Query: 129 ELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDV 188
+G GSS P AL +Q P S VP+
Sbjct: 1066 HHGSAGGGGGSSQGP---ALRYFQLPPRAASAAMYVPARSG------------------- 1103
Query: 189 LHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH-----LPT 243
+ + P V + GG L PA P+ T P P PP P +PT
Sbjct: 1104 ---RGRKGPLVKQTKVEGEPQKGGGLPPA---PSPTSPASPQPPPAVAAPSEKNSIPIPT 1157
Query: 244 QFNLLASSSAAAAAAEQSSPQLY-----------NFSGAAPGPPPPERALPRQDTVIKHY 292
S+S++ +++ SS + G++P P P +P + +
Sbjct: 1158 IIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV--- 1214
Query: 293 QRPASAQPPPPPPPAHALQHYLSCGGSYPSMG-------HRANLACSPLGGGEPSPGAGE 345
P A P P Q + G+ G R+ L S G E G
Sbjct: 1215 --PTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGL 1272
Query: 346 PSKAGP-------------------------SGATAGASGRATGPEAAGGGGAGGGGGGY 380
+ A P +G+ AG G G A GGGG +
Sbjct: 1273 GTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSF 1332
Query: 381 RPIIQSPGYKTGKG-------GYGAAA-----------GGATRPPP----PRSTATPKCQ 418
P TGK G AA GGA +PPP PR A P
Sbjct: 1333 LPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTP 1392
Query: 419 SLGGPAAAY--------------ATGKASGAGGAGGQAYS-PGQPQGL-------LGPQA 456
P A + A + G G Q S P P L P A
Sbjct: 1393 HHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTA 1452
Query: 457 YGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPG--------LATCQSYSPDQLQGQLYG 508
G G Q AP P + P P L CQ +P
Sbjct: 1453 PGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAP--------- 1503
Query: 509 VQGEPYPGPAAHSQGLPTASPSLSYSTGH-SPALSGHGG----GWGPSSLGGGGEASPSH 563
V P P+ G+P SP S SP S G P + E
Sbjct: 1504 VTSGRGP-PSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFL 1562
Query: 564 IIRPL-------------QSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAA 610
+ PL +SP G P + AP L V A APP S A+
Sbjct: 1563 FVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS 1622
Query: 611 GAGGYKGK----GDGSELLAG---PGGPPAERTE----------------------DEEF 641
Y + G+ G P GPPA D
Sbjct: 1623 SLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRS 1682
Query: 642 LIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQ 701
H L+ S T + L E G + G G+G A GP +A D Q +
Sbjct: 1683 SSDHPLETISSASTLSS--LSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS 1740
Query: 702 SV--------IRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGA 753
S + T + L A A G L+ G R TP SV GAG
Sbjct: 1741 STPGPPYPPQLMTPSKLRGRALGAS----GGLRPGPSGGLRDPVTPTSPTVSVT--GAGT 1794
Query: 754 KELGAFLQKSPPP---------------PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP 798
L A S PP PP + P LL GP PPPP
Sbjct: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPG-----PPPP 1849
Query: 799 PQLLPSVLSHAPSPSPSASKVGVHLLEPATR----DGAPQPPPPPPPPPPPMPLQLEAHL 854
P LP L+ + + + K + + E +++ G+ P ++H
Sbjct: 1850 P--LPGPLAQPQASALATVKASI-ISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHH 1906
Query: 855 RSHGLEPAAPSPRLRPEESLDPPGAM-QELLGAL------EPLPPAPGDTGVGPPNSE-- 905
P S R S D ++ + + +L PLPP P TGV P +
Sbjct: 1907 GGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAP 1966
Query: 906 -GKDPAGAYRSPSP---QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
P+ + S S QG + PL SLL E P
Sbjct: 1967 GATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSG 2026
Query: 962 YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGL--GLDPNK----P 1015
G + G P GAG P A + P PG + G G G L P + P
Sbjct: 2027 PLYPGLFDIRGSPTGGAGGSADPFA-PVFVPPHPGISGGLGGALSGASRSLSPTRLLSLP 2085
Query: 1016 PELPSTVNAEPLG 1028
P+ P A+PLG
Sbjct: 2086 PDKP--FGAKPLG 2096
Score = 51.6 bits (122), Expect = 8e-06
Identities = 111/487 (22%), Positives = 146/487 (29%), Gaps = 116/487 (23%)
Query: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG 1204
P P P P R P P P +R ++P D A++ G
Sbjct: 1374 PQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLR----------LWGASPPDPARRELGYR 1423
Query: 1205 RGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEG-----LGTSSGDAISGTDHNSLDSSLT 1259
G G + + + + L +L G G LGT G ++
Sbjct: 1424 AGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPE 1483
Query: 1260 R-EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVP 1318
E++ ++ +E QP + SG R PP PP SP +SVPPS
Sbjct: 1484 EPERLPLHVRFLENCQPRAP----------VTSG-RGPPSEDGPGVPPPSPRRSVPPSPT 1532
Query: 1319 ARGLQPQ--------PPATPAV-----------PHPPPSGAFGLGGALEAAESEGLGLGC 1359
+ + PP P+V P PPP + E ES L G
Sbjct: 1533 SPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPP---LEFSNSFEKPESP-LTPGP 1588
Query: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
P P P + ++ S S ++ L A P D P
Sbjct: 1589 PHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648
Query: 1420 DGPPL----APAAAVPGPPPLPGLPSA----NSNGTPEPPLLEEKPPPTPPP-------- 1463
GPP APAA PGP P PG S +S + + PL T
Sbjct: 1649 -GPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGS 1707
Query: 1464 -----------APTPQ----------------PQPPPPPPPPQPALPSP--------PPL 1488
A P+ P PP PPQ PS
Sbjct: 1708 AGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGG 1767
Query: 1489 VAPTPSSPPPPPLPPPPPPAMP--------------SPPPPPPPAAAPLAAPPEEPAAPS 1534
+ P PS P+ P P S PP A P+A PE P P
Sbjct: 1768 LRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPL 1827
Query: 1535 PEDPELP 1541
P LP
Sbjct: 1828 PTASSLP 1834
Score = 49.7 bits (117), Expect = 3e-05
Identities = 238/1103 (21%), Positives = 317/1103 (28%), Gaps = 282/1103 (25%)
Query: 824 LEPATRDGAPQPPPPPPPPPPPM---PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA- 879
++ A APQ PPP + + E + +PA P P + + ++
Sbjct: 762 MDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEMEYEQQPA-PVPSMEKKRTVYQMALN 820
Query: 880 -MQELLGALEPLPPAPGDTGVGPPNSEGKD-PAGAYRSPS---PQGTKAPRFVPLTSICF 934
+ E+L A + A G G S GK P G + + S P P +
Sbjct: 821 KLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSY-------- 872
Query: 935 PDSLLQDEERSFFPT-----MEEMFGGGAADDYGKAGPPE-----------DEGDPKAGA 978
E SF P + + G A DD PP E P
Sbjct: 873 -------ERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPT 925
Query: 979 GPPPGPPAYDPYGPYCPGRASGA---GPETPGLG--LDPNKP-----PELPST-VNAEPL 1027
PP PP P P GR + + GP PG G L + P P P T V +
Sbjct: 926 TSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREK 985
Query: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087
L SGP A PP AP +P H PP
Sbjct: 986 SLYHSGPLPPAHHHPPHHHHHHAPPPQPH---------------------HHHAHPPHPP 1024
Query: 1088 FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP 1147
E E D P + L P+ P L P+ P P
Sbjct: 1025 ------------EMETGGSPDDPPPRLALGPQ--PSLRGWRGGGPS-----------PTP 1059
Query: 1148 GPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGR 1207
G P G + G +G P +R ++P A A+ P GR
Sbjct: 1060 GAPSPSHHG-----SAGGGGGSSQG-PALRYFQLPPRAASAAMYVPARS---------GR 1104
Query: 1208 GRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKI 1267
GRK T++E P+ G GL + + + EK I
Sbjct: 1105 GRKGPLVKQTKVE---------GEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPI 1155
Query: 1268 KEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPP 1327
+ K P S +S ++ P G S P PA + P PP
Sbjct: 1156 PTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPS------PAPAMSPVPP 1209
Query: 1328 ATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKR----LDEELKRNLETLPSFSSD 1383
+ P P P+ A G A S+ G +R +E +R+ L + + D
Sbjct: 1210 S----PSPVPTPASPSGPATLDFTSQ-FGAALVGAARREGGWQNEARRRSTLFLSTDAGD 1264
Query: 1384 EEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP----GPPPLPGL 1439
E+ G T GP L + ++ P L
Sbjct: 1265 EDGG-----------------------DGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRL 1301
Query: 1440 PSANSN--------------GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
SA S G PP P P P P
Sbjct: 1302 ESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARE 1361
Query: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA----APSPEDPELP 1541
L + P P P PP P +PPP P +P A EP SP DP
Sbjct: 1362 RALKESSEGGGAPQPPPRPPSPRYEAPPPT-PHHHSPHAH--HEPVLRLWGASPPDPA-- 1416
Query: 1542 DTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSL-KLALQTGREP 1600
++E G +E R R P + L LQ G EP
Sbjct: 1417 ---------RRELGYRAGLGSQEKSLPASPPAAR-RSLLHRLPPTAPGVGPLLLQLGTEP 1466
Query: 1601 PPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVR 1660
P + PE + L+V+FLEN
Sbjct: 1467 PAPHPGVSKPWRSAAPE---------------------EPERLPLHVRFLENC------- 1498
Query: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQT-- 1718
+P PV + P S G PPP P+ P TS + E+
Sbjct: 1499 --------QPRAPVT---SGRGPPSEDGPGVPPPS-----PRRSVPPSPTSPRASEENGL 1542
Query: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE----RPLRGERATSGRQTRPERSLATG 1774
P +P PPAP V GE PL S +PE L G
Sbjct: 1543 PLLVLP-PPAPSVD--------------VEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG 1587
Query: 1775 QP--------ATSRLPKARPTKVKAEPPP-----------KKRKKWLKEAGGNATAGGGP 1815
P + LP P V A PP L + A P
Sbjct: 1588 PPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHP 1647
Query: 1816 PGSSSDSESSPGAPSEDERAVPG 1838
PG + + +P AP PG
Sbjct: 1648 PGPPAPAAPAPAAPQPGPDPPPG 1670
Score = 45.4 bits (106), Expect = 6e-04
Identities = 112/450 (24%), Positives = 151/450 (33%), Gaps = 104/450 (23%)
Query: 51 AAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLL 110
++ HPL++ ++ + LS L G AG G + G GP
Sbjct: 1683 SSDHPLETISS---ASTLSSLSAEGGGSAGGGGGAGA-----------GVASGPELLDTY 1728
Query: 111 SQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSL 170
+ TPGP P + S L AS G RP P S L
Sbjct: 1729 VAYLDGQAFGGSSTPGP---------PYPPQLMTPSKLRGRALGASGGLRPGP---SGGL 1776
Query: 171 QDP--PFSPPANGLLSPHD-VLHLKPSQAPTVPSSLGFERLAGGGV-----LGPAGLGPA 222
+DP P SP + + D +L L+ P +AGG V + P L A
Sbjct: 1777 RDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAG------VAGGPVAVEPEVPPVPLPTA 1830
Query: 223 QTPPYR-------PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275
+ P + PGPP PP P Q + LA+ A+ + S Q + S AA G
Sbjct: 1831 SSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGA 1890
Query: 276 PP--------------------PER--ALPRQ----DTVIKHYQRPASA------QPPPP 303
P PER +L RQ D+ +P S+ +PP P
Sbjct: 1891 LPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLP 1950
Query: 304 P--------PPAHALQHYLSCGGSYPSMGHRANLACS-----PLGGGEPSPG--AGEPSK 348
P P A A S S S R PL PSP K
Sbjct: 1951 PLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHK 2010
Query: 349 AGPSGATAGASGRATGPEAAG--------GGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
P+ + +GP G GGAGG + P+ P + GG G A
Sbjct: 2011 VSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPP-HPGISGGLGGAL 2069
Query: 401 GGATRP-PPPRSTATPKCQSLGGPAAAYAT 429
GA+R P R + P + G + T
Sbjct: 2070 SGASRSLSPTRLLSLPPDKPFGAKPLGFWT 2099
Score = 32.7 bits (73), Expect = 3.7
Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%)
Query: 260 QSSPQLYNFSGAAPGPP------PPERALPRQDTVIKH-----YQRPASAQPPPPPPPAH 308
Q SP+ ++ GPP PP DT + + P +A P P +
Sbjct: 411 QESPK---YAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSG 467
Query: 309 ALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAG---EPSKAGPSGATAGASGRATGP 365
+ + A SP G SP G E +K P G + + GP
Sbjct: 468 SQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGP 527
Query: 366 EAAGGGGAGGGGG 378
A G GG+GG GG
Sbjct: 528 -AGGTGGSGGPGG 539
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 137 bits (345), Expect = 1e-31
Identities = 251/936 (26%), Positives = 306/936 (32%), Gaps = 176/936 (18%)
Query: 194 SQAPTVPSSLGFERLAGG----GVLGPAGLGPAQTPPYRPGPPDPPPPP---------RH 240
S++PT + G E G G GPAG P +PG P PP PP +
Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGN 158
Query: 241 LPTQFNLLASSSAAAAAA-----EQSSPQLYNFSGAAPGP-----PPPERALPRQDTVIK 290
Q + + + S P+ APGP PP E P
Sbjct: 159 FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGA----- 213
Query: 291 HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPG-AGEPSKA 349
P + PP PP + G G L G PG G +
Sbjct: 214 --SGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFS 271
Query: 350 GPSGA--TAGASGRATGPEAAGGGGAGGGGG-----GYRPIIQSPGYKTGKGGYGAAAGG 402
G GA AG +G P + G GA G G G R +PG +G GA G
Sbjct: 272 GLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGAT--G 329
Query: 403 ATRPPPPRSTATPKCQSLGGPAAAYATGKA--------SGAGGAGGQAYSPGQPQGLLGP 454
A PP P A P G P A A G+A G G G+ PG P G GP
Sbjct: 330 AAGPPGPTGPAGPP----GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPG-PAGAAGP 384
Query: 455 QAYGQGFGGGQAQDLSKAPSYSGGP----------PQPPSGPPPPGLATCQSYSPDQLQG 504
G A+ + AP +G P PQ P GPP P + + +P +G
Sbjct: 385 AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGS-KG 443
Query: 505 QLYGVQGEP-------YPGPA-------AHSQGLPTASPSLSYSTG--HSPALSGHGGGW 548
G +GEP PGPA A + PT P G S G G
Sbjct: 444 DT-GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA 502
Query: 549 GPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSY 608
GP G GE P SP GRP G PGA G L +P P +
Sbjct: 503 GPK--GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG------LTGSPGSPGPDGKTG 554
Query: 609 AAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG-- 666
G G G+ GP GPP R + ++ P P +G G GE G
Sbjct: 555 PPGPAGQDGR-------PGPPGPPGARGQ------AGVMGFPGPKGAAGEPGKAGERGVP 601
Query: 667 ---AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLG 723
A G G GA GPPG P A E + Q + A G
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPG-PAGPAGERGE----QGPAGSPGFQGLPGPAGPPGEAG 656
Query: 724 RLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLL 783
+ E+ + G P G G E G +Q P P P + P G
Sbjct: 657 KPGEQGVPGDLGAPGPSGARGERGFPG----ERG--VQGPPGPAGPRGANGAPGNDGAKG 710
Query: 784 EAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPP---PP 840
+AG P P P Q +P A P P + P DG+P
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA---GPKGADGSPGKDGVRGLTG 767
Query: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG 900
P PP P G P+ P+ P GA EP PP P G
Sbjct: 768 PIGPPGPAGAPGDKGESG--PSGPA---------GPTGARGAPGDRGEPGPPGPAGF-AG 815
Query: 901 PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAAD 960
PP ++G+ GA P G K P G A
Sbjct: 816 PPGADGQ--PGAKGEPGDAGAKGDAGPP----------------------------GPAG 845
Query: 961 DYGKAGPPEDEGDPKA-GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELP 1019
G GP + G P A GA GPP + PG A GP P P PP
Sbjct: 846 PAGPPGPIGNVGAPGAKGARGSAGPPGATGF----PGAAGRVGPPGPSGNAGPPGPPGPA 901
Query: 1020 STVNAE-PLGLIQSGPHQAAPPPPPPPPPPPAPASE 1054
+ P G ++GP A P PP PP PA E
Sbjct: 902 GKEGGKGPRG--ETGP--AGRPGEVGPPGPPGPAGE 933
Score = 134 bits (337), Expect = 9e-31
Identities = 282/1033 (27%), Positives = 337/1033 (32%), Gaps = 217/1033 (21%)
Query: 164 VPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQ 223
+P L PP P P L + AP + S G++ + GG+ P +GP+
Sbjct: 134 IPGQPGLPGPPGPP------GPPGPPGLGGNFAPQL--SYGYDEKSTGGISVPGPMGPSG 185
Query: 224 TPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALP 283
P PGPP P P F A+ P+ PGPP
Sbjct: 186 -PRGLPGPPGAPGPQG-----FQGPPGEPGEPGASGPMGPR------GPPGPPGKNG--- 230
Query: 284 RQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHR-------ANLACSPLGG 336
D RP + PP P A L G GHR A P G
Sbjct: 231 -DDGEAGKPGRPGE-RGPPGPQGARGLPGTAGLPGM---KGHRGFSGLDGAKGDAGPAGP 285
Query: 337 -GEP-SPGA-GEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGK 393
GEP SPG G P + GP G G GR P AG G G G P P G
Sbjct: 286 KGEPGSPGENGAPGQMGPRGLP-GERGRPGAPGPAGARGNDGATGAAGP--PGPTGPAGP 342
Query: 394 GGYGAAAG--GATRPPPPRSTATPKCQ--SLGGPAAAYATGKAS-----------GAGGA 438
G+ A G G P PR + P+ G P A A G A GA GA
Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402
Query: 439 GGQAYSPGQP--QGLLGPQAYG-----QGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL 491
G A +PG P +G GPQ G +G G SK + + G P P PPG
Sbjct: 403 PGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG- 461
Query: 492 ATCQSYSPDQLQGQLYGVQGEP----YPGPAAH-----SQGLP----TASPSLSYSTGHS 538
P +G+ G +GEP PGP S+G P A P S
Sbjct: 462 -------PAGEEGKR-GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513
Query: 539 PALSGHGGGWGPSS-------------LGGGGEASPSHIIRPLQSPPATGRPPGVGSPGA 585
P +G G G + G G P P GRP G PGA
Sbjct: 514 PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573
Query: 586 ------------------PGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG-------KGD 620
PGK + P P AGA G G +G+
Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE 633
Query: 621 -------GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD---- 669
G + L GP GPP E + E + L AP P G G GE G
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693
Query: 670 ----ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASL--------DEGATAA 717
+ G G+ GA G G P + R +A L D G A
Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753
Query: 718 -----------LELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP 766
L +G ++G P G A GA G + PP
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP----GDRGEPGPPG 809
Query: 767 P-----PPTAQSTQPTPHGLLLEAG-----GPDLPLVLPPPPPQLLPSVLSHAPSPSPSA 816
P PP A QP G +AG GP P PP + A SA
Sbjct: 810 PAGFAGPPGADG-QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 817 SKVGVHLLEPAT-RDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
G A R G P P PP PP P E G P RP E +
Sbjct: 869 GPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRG----ETGPAGRPGE-VG 923
Query: 876 PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935
PPG PP P G P ++G PAGA +P PQG R V + P
Sbjct: 924 PPG------------PPGPAGE-KGSPGADG--PAGAPGTPGPQGIAGQRGV----VGLP 964
Query: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD--PKAGAGPP--PGPPAYD--- 988
Q ER FP + G + + GK GP G+ P GPP GPP
Sbjct: 965 G---QRGERG-FPGLP-----GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015
Query: 989 --PYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAE-PLGLI-QSGPHQAAPPPPPP 1044
P PGR G + P PP P A P+G +SG P P
Sbjct: 1016 GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPA 1075
Query: 1045 PPPPPAPASEPKG 1057
P P A P G
Sbjct: 1076 GPVGPVGARGPAG 1088
Score = 123 bits (309), Expect = 2e-27
Identities = 267/1039 (25%), Positives = 330/1039 (31%), Gaps = 211/1039 (20%)
Query: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
P+ P P ++G + G GP G ++ P G P PP P N A
Sbjct: 339 PAGPPGFPGAVGAK-----GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQH 312
A A +P + APG P + P+ Q P PP
Sbjct: 394 PGAKGAN-GAPGI----AGAPGFPGA--------------RGPSGPQGPGGPPGPKGNSG 434
Query: 313 YLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA-----GASGRATGPEA 367
GS G + P+G P AGE K G G G G GP +
Sbjct: 435 EPGAPGSKGDTGAKGEPG--PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492
Query: 368 AGGGGAGGGGGGYRPIIQ--SPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAA 425
G GA G G P + SPG KG G A P P + L G
Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-------PGEAGLPGAKGLTGSPG 545
Query: 426 AYATGKASGAGGAGGQAYSPGQP--QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPP 483
+ +G G GQ PG P G G QA GF G + + G P PP
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARG-QAGVMGFPGPKGAAGEPGKAGERGVPGPP 604
Query: 484 SGPPPPGL-ATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLP-TASPSLSYSTGHSPAL 541
P G + P G G +GE P + QGLP A P +
Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPA-GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGV 663
Query: 542 SGHGGGWGPSSLGGGGEAS-PSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL 600
G G GPS G GE P R +Q PP P G GAPG + A AP
Sbjct: 664 PGDLGAPGPS--GARGERGFPGE--RGVQGPPGPAGPRGAN--GAPGNDGAKGDAGAP-- 715
Query: 601 APPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADG 660
PG+ GA G +G G AG GP +R + + P+ GADG
Sbjct: 716 GAPGS----QGAPGLQGM-PGERGAAGLPGPKGDRGD-------------AGPK--GADG 755
Query: 661 LVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL 720
G+DG +GL G G GP G P + + P S G T A
Sbjct: 756 SPGKDGV----RGLTGPIGPPGPAGAPGDKGESGP-------------SGPAGPTGARGA 798
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG 780
R + GP G P G GA + A + PP P + P P G
Sbjct: 799 PGDRGEPGPPGPA-GFAGPPGADGQP---GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854
Query: 781 LLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQP----- 835
+ G PP P P PS + PA ++G P
Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETG 914
Query: 836 ----PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLG--ALEP 889
P PP PP P + P A P P PG Q + G +
Sbjct: 915 PAGRPGEVGPPGPPGPAGEKG-------SPGADGPAGAP----GTPGP-QGIAGQRGVVG 962
Query: 890 LPPAPGDTGV----GPPNSEGKD-PAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
LP G+ G GP GK P+GA P G P + P + R
Sbjct: 963 LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGP-----PGLAGPPG---ESGR 1014
Query: 945 SFFPTMEEMFGG----GAADDYGKAGPPEDEGDPKAGAGPPPGPPA-----------YDP 989
P E G GA D G+ GP G P A P P PA P
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074
Query: 990 YGPYCPGRASG-AGPETP-------------GL-------GLD-PNKPPELPST------ 1021
GP P A G AGP+ P G+ GL P PP P
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134
Query: 1022 --------------------VNAEPLGLIQSGPH----QAAPPPPPPPPPPPAPASEPKG 1057
+N P + GP A P PP PP PP P P
Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194
Query: 1058 GLTSPIFCSTKPKK------LLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVP 1111
G +K + +++R RD T K +Q+ E P
Sbjct: 1195 GFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIE------NIRSP 1248
Query: 1112 ADIRLNPRRLPDLVSSCRS 1130
R NP R + C S
Sbjct: 1249 EGSRKNPARTCRDLKMCHS 1267
Score = 118 bits (296), Expect = 5e-26
Identities = 232/824 (28%), Positives = 274/824 (33%), Gaps = 163/824 (19%)
Query: 98 RGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASF 157
+GP PGP+ R T + PGP PGS FP + ++ + PA
Sbjct: 457 QGP-PGPAGEEGKRGARGEPGPTGL--PGPPG---ERGGPGSRGFPGADGVAGPKGPA-- 508
Query: 158 GSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPA 217
G R P P+ P SP G +P +A +P + G G GP
Sbjct: 509 GERGSPGPAG-----PKGSPGEAG----------RPGEAG-LPGAKGLTGSPGSP--GPD 550
Query: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP- 276
G P + G P PP PP Q ++ AA E PGPP
Sbjct: 551 GKTGPPGPAGQDGRPGPPGPPG-ARGQAGVMGFPGPKGAAGEPGKAG----ERGVPGPPG 605
Query: 277 ---------------PPERALPRQDTVIKHYQRPASAQ-----PPPPPPPAHALQHYLSC 316
PP A P + + Q PA + P P PP A
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGE---RGEQGPAGSPGFQGLPGPAGPPGEA------- 655
Query: 317 GGSYPSMGHRANL-ACSPLG--GGEPSPGA----GEPSKAGPSGATA-----GASGRATG 364
G G +L A P G G PG G P AGP GA GA G A
Sbjct: 656 -GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714
Query: 365 PEAAGGGGAGG--GGGGYRPIIQSPGYKTGKGGYGAAAG----------GATRP-PPPRS 411
P A G GA G G G R PG K +G G G T P PP
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774
Query: 412 TATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSK 471
P + GP+ A GA G G+ PG P G GP G G + +
Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG-PAGFAGPPG-ADGQPGAKGEPGDA 832
Query: 472 APSYSGGPPQP--PSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTAS- 528
GPP P P+GPP P G G P A S G P A+
Sbjct: 833 GAKGDAGPPGPAGPAGPPGP-----------------IGNVGAPGAKGARGSAGPPGATG 875
Query: 529 -PSLSYSTGHSPALSGHGGGWGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGA 585
P + G P SG+ G GP G GG+ P GRP VG PG
Sbjct: 876 FPGAAGRVG-PPGPSGNAGPPGPPGPAGKEGGKG-------PRGETGPAGRPGEVGPPGP 927
Query: 586 PGKY--LSSVLASAPFLAP--PGAGSYAAGAG-----GYKGKGDGSELLAGPGGPPAERT 636
PG S A P AP PG A G G +G+ G L GP G P ++
Sbjct: 928 PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER-GFPGLPGPSGEPGKQG 986
Query: 637 EDEEFLIQHLLQAPSPPRTSGADGLVGEDGA--ADASKGLGGSGGA---------GGPPG 685
+ PP +G G G +GA A+ S G GS GA GPPG
Sbjct: 987 PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046
Query: 686 TPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATS 745
P P V S D G T +GP G + P G
Sbjct: 1047 APGAPGAPGP-------VGPAGKSGDRGETGPAGPAGPVGPVGARGPA-GPQGPRGDKGE 1098
Query: 746 VVHYG-AGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPS 804
G G K F PP PP + Q P G A GP P P
Sbjct: 1099 TGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG-PSG----ASGPAGPRGPPGSAGAPGKD 1153
Query: 805 VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP-PPPPPMP 847
L+ P P G T D P PP PP PP PP P
Sbjct: 1154 GLNGLPGPIGPPGPRG------RTGDAGPVGPPGPPGPPGPPGP 1191
Score = 117 bits (294), Expect = 9e-26
Identities = 308/1226 (25%), Positives = 383/1226 (31%), Gaps = 182/1226 (14%)
Query: 341 PGA----GEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
PGA GE P G+ + TG E G G G P G+ G
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRG-------PAGPPGRDGI 134
Query: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA 456
G P PP P P +Y + S G + P P+GL GP
Sbjct: 135 PGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPG 194
Query: 457 YG--QGFGGGQAQDLSKAPSYSGGPPQPPSGPP-PPGLATCQSYSPDQLQGQLYGVQGEP 513
QGF G + P SG P P GPP PPG + D + G GE
Sbjct: 195 APGPQGFQGPPGEP--GEPGASG--PMGPRGPPGPPGK------NGDDGEAGKPGRPGER 244
Query: 514 YPGPAAHSQGLPTAS--PSLSYSTGHSPALSGHGGGWGPSSLGGGGE-ASPSHIIRPLQS 570
P ++GLP + P + G S L G G GP+ G GE SP P Q
Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFS-GLDGAKGDAGPA--GPKGEPGSPGENGAPGQM 301
Query: 571 PPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGG 630
P G P G PGAPG + A A P + AG G+ G G++ AGP G
Sbjct: 302 GPR-GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPG-AVGAKGEAGPQG 359
Query: 631 PPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA--ADASKGLGGSGGAGGPPGTPY 688
P Q + P PP +GA G G GA +KG G+ G G PG P
Sbjct: 360 PRGSEGP------QGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413
Query: 689 ELAKEDPQ--------RYHLQSVIRTSASLDEGATA-----ALELGLGRLKEKKKGPERG 735
PQ + + + D GA ++ G E+ K RG
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 736 GETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLP 795
P GL G P P + P P AG P
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP------AGPKGSPGEAG 527
Query: 796 PPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR 855
P LP SP PA +DG P PP PP +
Sbjct: 528 RPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKG 587
Query: 856 SHGLEPAAPSPRLRPEESLDPPGAMQEL-----LGALEPLPPA--PGDTGV-GPPNSEG- 906
+ G EP R P PPGA+ GA P PA G+ G GP S G
Sbjct: 588 AAG-EPGKAGERGVP----GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642
Query: 907 ---KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
PAG P G + VP + P ER F G A G
Sbjct: 643 QGLPGPAGP---PGEAGKPGEQGVP-GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698
Query: 964 KAGPPEDEGDPKAGAGPPPGPPAYDPYGPY-CPGRASGAGPETPGLGLDPNKPPELPSTV 1022
G P ++G K AG P P + G PG AG P P +
Sbjct: 699 ANGAPGNDG-AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP 757
Query: 1023 NAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLR 1082
+ + + P PP P AP + + G + P T +
Sbjct: 758 GKDGV--------RGLTGPIGPPGPAGAPGDKGESGPSGPAG---------PTGARGAPG 800
Query: 1083 RRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDF 1142
R P +A + P D P + P P+G++
Sbjct: 801 DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG--PIGNVGA 858
Query: 1143 --CPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPT--DGAK 1198
G GP P A R GPP P G AGP P +G K
Sbjct: 859 PGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN-----------AGPPGPPGPAGKEGGK 907
Query: 1199 KPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSL 1258
PRG GR E + P P P G+ D +G +
Sbjct: 908 GPRGETGPAGRPGE------VGPPGP-------PGPAGEKGSPGADGPAGAPGTPGPQGI 954
Query: 1259 TREK--IEAKIKEVEEKQPEMK--SGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSV- 1313
++ + + E P + SG SG+R PP P+ PP
Sbjct: 955 AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP-------GPMGPPGLAG 1007
Query: 1314 PPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL--GLGCPSPCKRLDEELK 1371
PP R P +P P GA G G A G G P P +
Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSP--GAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065
Query: 1372 RNLETLPSFSSD------------------EEDSVAKNRDLQESISSAISALDDPP---- 1409
R ET P+ + ++ + D S L PP
Sbjct: 1066 RG-ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124
Query: 1410 ---LAGPKDTSTPDGPPLAPAAA-VPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465
GP S P GP P +A PG L GLP G P P P PP P
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLP--GPIGPPGPRGRTGDAGPVGPPGP 1182
Query: 1466 TPQPQPPPPPPPPQPA-----LPSPP 1486
P PP PP PP LP PP
Sbjct: 1183 ---PGPPGPPGPPSAGFDFSFLPQPP 1205
Score = 94.4 bits (233), Expect = 1e-18
Identities = 301/1204 (25%), Positives = 363/1204 (30%), Gaps = 287/1204 (23%)
Query: 448 PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQG-QL 506
P+G GP+ +G G +D GPP PP P PPGL +++P G
Sbjct: 113 PKGDTGPRG-PRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGG--NFAPQLSYGYDE 169
Query: 507 YGVQGEPYPGPAAHS--QGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHI 564
G PGP S +GLP P G G GP G GE S
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGP-----------PGAPGPQGFQGPP--GEPGEPGASGP 216
Query: 565 IRPLQSPPATGRPPG-------VGSPGAPGKYLSSVLASAPFLAPPGAGSY-----AAGA 612
+ P + PP PPG G PG PG+ PPG AG
Sbjct: 217 MGP-RGPPG---PPGKNGDDGEAGKPGRPGER-----------GPPGPQGARGLPGTAGL 261
Query: 613 GGYKGKG-----DGSELLAGPGGP------PAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
G KG DG++ AGP GP P E + + L P G G
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELG 721
G DGA A+ G G G GPPG P GA A
Sbjct: 322 RGNDGATGAA-GPPGPTGPAGPPGFP-------------------------GAVGA---- 351
Query: 722 LGRLKEKKKGPE--RGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPH 779
+ + GP+ RG E P+G+ + P PP A + P
Sbjct: 352 -----KGEAGPQGPRGSEGPQGV-------------------RGEPGPPGPAGAAGP--- 384
Query: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
AG P P + + GA P P
Sbjct: 385 -----AGNPGAD------------------GQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P PP P + + EP AP S GA E PG GV
Sbjct: 422 GPGGPPGP-------KGNSGEPGAPG-------SKGDTGAKGE-----------PGPVGV 456
Query: 900 -GPPNSEGKD-PAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGG 957
GPP G++ GA P P G P P R F G
Sbjct: 457 QGPPGPAGEEGKRGARGEPGPTGLPGP----------PGERGGPGSRGF---------PG 497
Query: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAG-PETPGLGLDPNKPP 1016
A G GP + G P G P G P GR AG P GL P P
Sbjct: 498 ADGVAGPKGPAGERGSP--GPAGPKGSPGE-------AGRPGEAGLPGAKGLTGSPGSPG 548
Query: 1017 ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
T P G Q G P PP PP A G P + +P K
Sbjct: 549 PDGKTGPPGPAG--QDGR-------PGPPGPPGARGQAGVMGFPGPKGAAGEPGKA---- 595
Query: 1077 SFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSP 1136
R P P + + EA PA R P
Sbjct: 596 -----GERGVP-GPPGAVGPAGKDGEAGAQGPPGPA-------------GPAGERGEQGP 636
Query: 1137 LGDIDFCPPNPGPDGPRRRGRKPTKAKRDGP---PRP------RGRPRIRPLEVPT-TAG 1186
G F PGP GP KP + G P P RG P R ++ P AG
Sbjct: 637 AGSPGF-QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695
Query: 1187 P--ASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEG-LGTSSG 1243
P A+ + DGAK G G ++ A G + P + L PK G G
Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPG--SQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753
Query: 1244 DAISGTDH-NSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAG 1302
D G D L + + E P +G + G+ PP
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813
Query: 1303 LTPPLSP----PKSVPPSVPARG-LQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL-- 1355
PP + K P A+G P PA PA P P P G G GA A S G
Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGP-PGPIGNVGAPGAKGARGSAGPPG 872
Query: 1356 GLGCPSPCKRLDE---ELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
G P R+ P + E + + P AG
Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932
Query: 1413 PKDTSTPDGPPLAPAAAVP----GPPPLPGLPSANSN-GTPEPPLLEEKPPPTPPPAPTP 1467
K + DGP AP P G + GLP G P P +P P +
Sbjct: 933 EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASG 992
Query: 1468 QPQPPPPPPPPQPALPSPP--------PLVAPTPSSPPPP----------PLPPPPPPAM 1509
+ PP P PP L PP P +P P P PP P
Sbjct: 993 ERGPPGPMGPP--GLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050
Query: 1510 PSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESG 1569
P P P PA PA P+ + P A Q GET GE G
Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP---AGPQGPRGDKGET----GEQG 1103
Query: 1570 GEGI 1573
GI
Sbjct: 1104 DRGI 1107
Score = 78.2 bits (191), Expect = 8e-14
Identities = 239/990 (24%), Positives = 308/990 (31%), Gaps = 191/990 (19%)
Query: 648 QAPSPPRTSGADGLVGEDG--------AADASKGLGGSGGAGGPPGTPYELAKEDPQRYH 699
++P+ T+G +G G+ G G+ G G GPPG P P
Sbjct: 100 ESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPP---GPPGPPGLG 156
Query: 700 LQSVIRTSASLDEGATAALELG--LGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELG 757
+ S DE +T + + +G + G P+G G E G
Sbjct: 157 GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPG----EPG 212
Query: 758 AFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSAS 817
A P PP P +G EAG P P PP PQ + A P
Sbjct: 213 ASGPMGPRGPPGP-----PGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGH 267
Query: 818 KVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP- 876
+ G L+ A D P P P P P PR P E P
Sbjct: 268 R-GFSGLDGAKGDAGPAGPKGEPGSP------------GENGAPGQMGPRGLPGERGRPG 314
Query: 877 ---PGAMQELLGALEPLPPAPGDTG-VGPPNSEGKDPAGAYRSPS-PQGTKAPRFVPLTS 931
P + GA P PG TG GPP G A P P+G++ P+ V
Sbjct: 315 APGPAGARGNDGATGAAGP-PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV---- 369
Query: 932 ICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKA-GAGPPPGPPAYDPY 990
E G A G AG P +G P A GA PG
Sbjct: 370 ------------------RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG---- 407
Query: 991 GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP---PPPP 1047
P PG +GP+ PG P P + EP G A P P PP
Sbjct: 408 APGFPGARGPSGPQGPG-------GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460
Query: 1048 PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQT-PKKLYAQEYEFEADED 1106
PA +G P P L R P + P + A E
Sbjct: 461 GPAGEEGKRGARGEP-----GPTGLPGPPG----ERGGPGSRGFPGADGVAGPKGPAGER 511
Query: 1107 KADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDG 1166
+ PA + +P RP + L +PG GP + P A +DG
Sbjct: 512 GSPGPAGPKGSPGEA--------GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563
Query: 1167 PPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLK 1226
P P G P R G A G P+G G KA E G
Sbjct: 564 RPGPPGPPGAR--------GQAGVM----GFPGPKGAA-GEPGKAGERG----------- 599
Query: 1227 IKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFL 1286
VP +G + D +G + E+ E+ P GF
Sbjct: 600 ----VPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER--------GEQGPAGSPGFQGL-- 645
Query: 1287 DFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPA-----------RGLQPQP-PATPAVPH 1334
G PP +AG P + P+ RG+Q P PA P +
Sbjct: 646 ----PGPAGPP-GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN 700
Query: 1335 PPPS--GAFGLGGALEAAESEGL-GL-GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAK 1390
P GA G GA A S+G GL G P +R LP D D+ K
Sbjct: 701 GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG---------ERGAAGLPGPKGDRGDAGPK 751
Query: 1391 NRDL---QESISSAISALDDPPLAGPKDTSTPDGP--PLAPAAA--VPGPPPLPGLPSAN 1443
D ++ + + P AG GP P P A PG PG P
Sbjct: 752 GADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPA 811
Query: 1444 SNGTPEPPLLEEKPPPTPPP--------APTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495
G PP + +P P A P P P PP P + +P A +
Sbjct: 812 --GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG 869
Query: 1496 PPPPP--------LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLH 1547
PP + PP P PP PP PA P P+ E+ P
Sbjct: 870 PPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG 929
Query: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRER 1577
A ++ + G G G +GI +R
Sbjct: 930 PAGEKGSPGADGPAG-APGTPGPQGIAGQR 958
Score = 45.8 bits (107), Expect = 4e-04
Identities = 51/176 (28%), Positives = 58/176 (32%), Gaps = 44/176 (25%)
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP-PTPPPAPTPQPQPPPPPPPPQPALPS 1484
P A VP P P + + T + E P T P P P PP + +P
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRG-----PAGPPGRDGIPG 136
Query: 1485 PPPLVAPTPSSPPPPPLPP-----------------------PPPPAMPSPP---PPPPP 1518
P L P P PP PP PP P P PS P P PP
Sbjct: 137 QPGL--PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPG 194
Query: 1519 AAAP--LAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
A P PP EP P P P P K + D EAG+ G G
Sbjct: 195 APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD--------DGEAGKPGRPG 242
Score = 45.1 bits (105), Expect = 7e-04
Identities = 50/180 (27%), Positives = 56/180 (31%), Gaps = 56/180 (31%)
Query: 1408 PPLAGPKDTSTPDGPPLAPAA-AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466
P G + + P GPP AP A PGP G P P P PA
Sbjct: 1030 PGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP 1089
Query: 1467 PQPQ-------------------------PPPPPPPPQ---------PALPSPPPLVA-- 1490
P+ PP PP P PA P PP A
Sbjct: 1090 QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGA 1149
Query: 1491 ---------PTPSSPPPP--------PLPPPPPPAMPSPPPPPPPA--AAPLAAPPEEPA 1531
P P PP P P+ PP PP P PP PP + L PP+E A
Sbjct: 1150 PGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKA 1209
Score = 37.4 bits (85), Expect = 0.15
Identities = 42/156 (26%), Positives = 52/156 (33%), Gaps = 21/156 (13%)
Query: 1685 SAGGSSAPPPKAPAP----PPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEK 1740
S GG S P P P+ P P P + PP + E P P P P K
Sbjct: 171 STGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP--GPPGK 228
Query: 1741 EKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTK-------VKAEP 1793
+ + + RP GER G Q A G P T+ LP + + K +
Sbjct: 229 NGDDGEAGKPGRP--GERGPPGPQG------ARGLPGTAGLPGMKGHRGFSGLDGAKGDA 280
Query: 1794 PPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAP 1829
P K G N G P PGAP
Sbjct: 281 GPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAP 316
Score = 36.6 bits (83), Expect = 0.26
Identities = 37/160 (23%), Positives = 54/160 (33%), Gaps = 12/160 (7%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P + G G + P P PP P + + P P T P+ A
Sbjct: 897 PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG 956
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
++ + P + RGER G SG + S A+G+ P
Sbjct: 957 QRGVVGLPGQ---------RGERGFPGLPGPSGEPGKQGPSGASGERGP---PGPMGPPG 1004
Query: 1790 KAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAP 1829
A PP + ++ A G+ G P E+ P P
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP 1044
Score = 35.8 bits (81), Expect = 0.44
Identities = 79/323 (24%), Positives = 98/323 (30%), Gaps = 62/323 (19%)
Query: 99 GPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFG 158
GP PGP+ P+ A TPGP + + G P+
Sbjct: 926 GP-PGPAGEKGSPGADGPAG--APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982
Query: 159 SRPFPVPSSLSLQDP-PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG----GV 213
+ P +S P P PP GL P AP S G + G G
Sbjct: 983 GKQGPSGASGERGPPGPMGPP--GLAGPPG--ESGREGAPGAEGSPGRDGSPGAKGDRGE 1038
Query: 214 LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP 273
GPAG PP PG P P P P + + A A P
Sbjct: 1039 TGPAG------PPGAPGAPGAPGPVG--PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQ 1090
Query: 274 GPPPPERALPRQ-DTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACS 332
GP + Q D IK ++ + Q PP PP
Sbjct: 1091 GPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP--------------------------- 1123
Query: 333 PLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTG 392
G P + GPSGA +G +G P +AG G G G PI P G
Sbjct: 1124 -----------GSPGEQGPSGA-SGPAGPRGPPGSAGAPGKDGLNGLPGPI--GPPGPRG 1169
Query: 393 KGGYGAAAGGATRPPPPRSTATP 415
+ G G P PP P
Sbjct: 1170 RTGDAGPVGPPGPPGPPGPPGPP 1192
Score = 35.4 bits (80), Expect = 0.57
Identities = 45/181 (24%), Positives = 63/181 (34%), Gaps = 16/181 (8%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTP-ETAMPEPPA 1728
PP P SG+ P S G + A P P P ++ P T +P PP
Sbjct: 426 PPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG 485
Query: 1729 PEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARP-T 1787
P + G + GER + G G+P + LP A+ T
Sbjct: 486 ERG----GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541
Query: 1788 KVKAEPPPKKRKKWLKEAGGNATAG-GGPPGSSSDS--------ESSPGAPSE-DERAVP 1837
P P + AG + G GPPG+ + + + G P + ER VP
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601
Query: 1838 G 1838
G
Sbjct: 602 G 602
Score = 33.9 bits (76), Expect = 1.7
Identities = 44/162 (27%), Positives = 54/162 (33%), Gaps = 16/162 (9%)
Query: 1683 PVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPE-------QTPETAMPEPPAP--EKPS 1733
P +AG P P A PP P P K P + E P PP P EK S
Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936
Query: 1734 LLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP-KARPTKVKAE 1792
P T G + + G+R G + G P S P K P+ E
Sbjct: 937 ---PGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993
Query: 1793 --PPPKKRKKWLKEAGGNATAGGGPPGSSSDS-ESSPGAPSE 1831
PP L G + G P S + SPGA +
Sbjct: 994 RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD 1035
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 133 bits (334), Expect = 2e-30
Identities = 210/814 (25%), Positives = 280/814 (34%), Gaps = 145/814 (17%)
Query: 817 SKVGVHLLEPATRDGA---PQPPPPPPPPPP--PMPLQLEAHLRSHGLEPAAP------- 864
+K G PA R P+PP P PPPP P L++ + G +P A
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 865 ------SPRLRPEESLDP----PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
+PR P S P + G E PPA +T GP +S G+ A
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK-NTSPGPVSSPGR--ASGTT 124
Query: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKA-GPPE---- 969
P P G K R + + + + P + G D G G P
Sbjct: 125 RPGPLGQKGLRISA-------EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 970 --------DEGDPKAGAGPPPGPPAYDPY------GPYCPGRASGAGPETPGLGLDPNKP 1015
+ G P+ P PP P + S A P G +P
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 1016 PELPSTVNAEPLGL-IQSGPHQAAPPPPPPPPPPPAPASEPKG--GLTSPIFCSTKPKKL 1072
+ +A PL +SGP P P P P +PKG L P T P+K
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP----KPKGLQALRPPQV--TPPRKD 291
Query: 1073 LKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKAD-VPADIRLNP---RRLPDLVSSC 1128
+ L P TP + ++ A +PA + +P LP S
Sbjct: 292 AAPALGPL---SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Query: 1129 RSRPALSPLGDIDFCPPNPGPDG----------------PRRRGRKPTKAKRDGPPRPRG 1172
+ P+L L PP+ P P + T PP P
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 1173 RPRIRPLEVPTTAG-PASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSV 1231
+ L+ T+ G P +T + PR + A P PL+ LS+
Sbjct: 409 ---LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP--PLQAPLSL 463
Query: 1232 PKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKS 1291
P A L TS A+S L S LT ++A + + P+ +
Sbjct: 464 P-ASPPLQTSLSPAVS-----PLSSPLTIHPLQA-LSSLASHSPQAPLSSLIM------- 509
Query: 1292 GKRHPPLY-QAGLTPPL--SPPKSV--PPSVPARGLQPQPPATPAVPHPPPSGAFGLGGA 1346
PPL Q+ L PP +PP S+ PP L P P T + P P
Sbjct: 510 ----PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH-------- 557
Query: 1347 LEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALD 1406
LE CP+PC + + T P + + + S + L
Sbjct: 558 LETPP-------CPAPCPL---QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 1407 DPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPP--------LLEE--K 1456
PPL+ P T P PP + PP P P + TP P LL+
Sbjct: 608 SPPLS-PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 1457 PPPTPP-PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515
PPP+PP AP P PP P P +PP L AP PP PP PP P+ PP
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 1516 PPP-AAAPLAAPPEEPAAP--SPEDPELPDTRPL 1546
PPP AA PL PP PA+P SP P PL
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760
Score = 124 bits (311), Expect = 9e-28
Identities = 203/767 (26%), Positives = 271/767 (35%), Gaps = 106/767 (13%)
Query: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM-PLQLEAHLRSHGLEPAAPSPRL 868
P+P + + T G P+P P P PP P + + H +P+ R
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 869 RPEES--LDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRS-PSPQGTKAPR 925
RP L P A + L + PL +P +G P++ G A A+ S P P+G +A R
Sbjct: 227 RPSAGGGLQRP-ASRSLSSSATPLS-SPARSG---PSARGTPRAPAHPSQPKPKGLQALR 281
Query: 926 FVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPP 985
P + D+ S P G A + PP D A PP PP
Sbjct: 282 -PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA----RPVPPPDNAATPLPATLPPSPP 336
Query: 986 AYDPYGPYCPGRASGAGPETPGLGLDPNKPP-ELPSTVNAEPLGLIQS--------GPHQ 1036
P P P S A P L P PP + P ++ P+ S PH
Sbjct: 337 LATPL-PLAPPSPS-APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 1037 AAPPPPPPPPPPPAPAS-EPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLY 1095
P PP P A +S + L SP L T SF + P QT L
Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPT--------LQATHSFLTMS----PRQTQASLT 442
Query: 1096 AQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRR 1155
+ D + A + L P L +S PA+SPL P
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLS--PAVSPLSSPLTIHPL--------- 489
Query: 1156 GRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAG 1215
+ + P P + PLE ++ P S TP P E
Sbjct: 490 -QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP---------PLENLP 539
Query: 1216 GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
PL+ L+ P + + + S LT E + P
Sbjct: 540 SLAPPPLQTASAPLTTPHL------ETPPCPAPCPLQAPPSPLTTPPPETP-SSIATPPP 592
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP----- 1330
+ + L L S PPL PP +PP P + A P PPA+P
Sbjct: 593 QAPPALASPPLQGLPS----PPLSPLATPPPQAPPXLALPPLQA---PPSPPASPPLSPL 645
Query: 1331 AVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFS--SDEEDSV 1388
A P P A + L+A S PSP + + PS + S S+
Sbjct: 646 ATPSPQAPNALAVH-LLQAPFSPP-----PSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP 1448
A LQ S S PP++ P T P PP A + PP P P + + TP
Sbjct: 700 AAP-PLQVPPSPPAS----PPMS-PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
Query: 1449 E---PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ--PALPSPPPLVAPTPSSPPPPPLPP 1503
PPLL P PP P P P PPPQ PAL +PP P+P + P P
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813
Query: 1504 PPPPAMP-----SPPPPPPP--AAAPLAAPPEEPAAPSPEDPELPDT 1543
P ++P +PPP PP AA L PP PA+P+ + P P T
Sbjct: 814 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Score = 102 bits (254), Expect = 4e-21
Identities = 250/1066 (23%), Positives = 323/1066 (30%), Gaps = 248/1066 (23%)
Query: 209 AGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF 268
AG PA P P PG P PPPP P +L AA A + +
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVT--PAALRVLG---AAGAVGRKPLAERAGG 64
Query: 269 SGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRAN 328
G A P RA P + S++ P PPA G RA
Sbjct: 65 IGGATIPESAPRAGPTRSA-------GTSSRNPASRPPASG-------------RGERAP 104
Query: 329 LACSPLGGGEPSPG-AGEPSKAGPSGATA--------GASGRATGP--EAAGGGGAGGGG 377
A + G SPG A ++ GP G A G+AT +A GA
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 378 GGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGG 437
G P SP AAG P P +A P+ + G + + + S
Sbjct: 165 SGPTPGTPSPAMARRS----RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 438 AGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSY 497
+ P GL P + +++ + G P+ P+ P P Q+
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
Query: 498 SPDQLQ----------GQLY----------GVQGEPYPGPAAHSQGLPTASPSLSYSTGH 537
P Q+ G L G + P P P + LP P
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP------- 333
Query: 538 SPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATG---RPPGVGSPGAPGKYLSSVL 594
SP L+ P L ++P + + L SPPAT PP + +P P + S+
Sbjct: 334 SPPLAT------PLPLAPPSPSAPPSL-QTLPSPPATPPSQAPPSMTTP--PMQAPPSLQ 384
Query: 595 ASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLI------QHLLQ 648
P P S + A + G P + T FL Q L
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS--FLTMSPRQTQASLT 442
Query: 649 APSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPG----TPYELAKEDPQRYHLQSVI 704
+PS P ++ D A L S PP +P P H +
Sbjct: 443 SPSRPASTPPDS-----PPLQAPLSLPAS-----PPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 705 RTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSP 764
+ AS A + + + P P L T + L
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN----------LPSLA 542
Query: 765 PPPPPTAQSTQPTPHGLLLEAG---------GPDLPLVLPPP--------PPQLLPSVLS 807
PPP TA + TPH LE P PL PPP PP P L+
Sbjct: 543 PPPLQTASAPLTTPH---LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 808 HAPS---PSPSASKVGVHLLEPATRDGAP--QPPPPPPPPPPPMPLQ---------LEAH 853
P PSP S + + P Q PP PP PP PL L H
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 854 LRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAY 913
L L P P P PP S P+
Sbjct: 660 L----------------------------LQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691
Query: 914 RSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGD 973
S +P AP PL P A+ + P +
Sbjct: 692 PSQAPPSLAAP---PLQVPPSPP---------------------ASPPMSPSATPPPQAP 727
Query: 974 PKAGAGP---PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI 1030
P A P PP PPA P P TP PP +P + A PL +
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSP----------SATP--------PPRVPPLLAAPPLQVP 769
Query: 1031 QSGPHQ--AAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPF 1088
S P +P PPP PPA A+ P L SP ++S + PP
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 1089 QTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPG 1148
Q P L A + VP P SP PP PG
Sbjct: 830 QAPPVLAAPLLQ---------VPPS------------------PPASPTLQAPRRPPTPG 862
Query: 1149 PDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPT 1194
PD G + T A GPP P R L P AG +S++T T
Sbjct: 863 PD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907
Score = 92.8 bits (229), Expect = 3e-18
Identities = 175/699 (25%), Positives = 234/699 (33%), Gaps = 160/699 (22%)
Query: 970 DEGDPKAGAGPPPGPPAYDPYGPYCPGRASGA-GPETPGLGLDPNKPPELPST------- 1021
D KA AG PA RA G P PG P PP P+
Sbjct: 2 DNKRDKAKAGAAARTPA---------ARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAA 50
Query: 1022 --VNAEPLGLIQSGPHQAAPPPPPPPPPPPA--------PASEPKG---GLTSPIFCSTK 1068
V +PL G A P P P PAS P G +P +T
Sbjct: 51 GAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS 110
Query: 1069 PKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR-------- 1120
P + R P Q ++ A+E +A + + RR
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170
Query: 1121 LPDLVSSCRSRPALSPLGDIDFCP---PNPGPDGPRRR--------GRKPTKAKRDGPPR 1169
P + RSR A + +G P P P +GPR+ +P+ A R P
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 1170 PRG--RPRIR-------PLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLE 1220
G RP R PL P +GP++ TP A + + +G L+
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG------------LQ 278
Query: 1221 PLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSG 1280
L+P ++ A LG S ++ + + A P S
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP---SP 335
Query: 1281 FMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGA 1340
+A+ L PP Q +PP +PP PPS+ +Q P P P
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
Query: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
+L+A PSP + +L + P+ + R Q S++S
Sbjct: 396 --TSPSLQAP---------PSPLALSSLQATTSLGS-PTLQATHSFLTMSPRQTQASLTS 443
Query: 1401 ----AISALDDPPLAGPKDTSTPDGPPL----APAAAVPGPP----PLPGLPSANSNGTP 1448
A + D PPL P S P PPL +PA + P PL L S S+
Sbjct: 444 PSRPASTPPDSPPLQAP--LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 1449 EP------PLLEEKPPPTPPPAPTPQPQPPPPP--------PPPQPALPSP--------P 1486
P P LE + PP TP PP PPP +P P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 1487 PLVAPTPSSPPPP--PLPPP--------PPP------------AMPSPP------PPP-- 1516
P AP P PP PPP PPP +PSPP PPP
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 1517 PP--AAAPLAAPPEEPAAP-----SPEDPELPDTRPLHL 1548
PP A PL APP PA+P + P+ P+ +HL
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Score = 92.0 bits (227), Expect = 5e-18
Identities = 292/1202 (24%), Positives = 376/1202 (31%), Gaps = 282/1202 (23%)
Query: 480 PQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSP 539
P+PP P PP T P L+ + G G P A G
Sbjct: 27 PRPPGSPRPPPPVT-----PAALR--VLGAAGAVGRKPLAERAG---------------- 63
Query: 540 ALSGHGGGWGPSSLGGGG--EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASA 597
G GG P S G ++ + P PPA+GR G P K S S+
Sbjct: 64 ---GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGR----GERAPPAKNTSPGPVSS 116
Query: 598 PFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSG 657
P A +G+ G G KG +E G + TE + + L A + TSG
Sbjct: 117 PGRA---SGTTRPGPLGQKGLRISAEETVARG----KATEAPK---RSALSAGARRDTSG 166
Query: 658 ADGLVGEDGAADASKGLGGSGGAGGP-----PGTPYELAKEDPQRYHLQSVIRTSA---- 708
A S+ G G P P P E ++ S S
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 709 --SLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP 766
S G L P R G + G + H + K G + P
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQV 285
Query: 767 PPPTAQSTQ------------PTPHGLLLEAGGPD------LPLVLPPPPPQLLPSVLSH 808
PP + P+P G P LP LPP PP P L+
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA- 344
Query: 809 APSPSPSASKVGVHLLEPATRDGAPQPPPPPPPP---PPPM----PLQLEAHLRSHGLEP 861
PSPSA L P + PP PP PP + P+Q+ L S L+
Sbjct: 345 --PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ- 401
Query: 862 AAPSP----RLRPEESLDPPGAMQELLGALEPLP-------PAPGDTGVGPPNSEG-KDP 909
A PSP L+ SL P +Q L P +P PP+S + P
Sbjct: 402 APPSPLALSSLQATTSLGSP-TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460
Query: 910 AGAYRSPSPQGTKAPRFVPLTS------ICFPDSLLQDEERS-----FFPTMEEMFGGGA 958
SP Q + +P PL+S + SL ++ P +E
Sbjct: 461 LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ----- 515
Query: 959 ADDYGKAGPPEDEGDPKAGAGPP-PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
PP + P + PP P+ P P + + A TP L P
Sbjct: 516 ----SSLAPPSLQTPPASLTTPPLENLPSLAPP----PLQTASAPLTTPHL---ETPPCP 564
Query: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSS 1077
P + A P L P + PPP PPA AS P GL SP P L T
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP------PLSPLAT-- 616
Query: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPL 1137
PP Q P L L P + P S + P LSPL
Sbjct: 617 --------PPPQAPPXL--------------------ALPPLQAPP---SPPASPPLSPL 645
Query: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGA 1197
P P P +A PP P P++ P + AS P +
Sbjct: 646 A-------TPSPQAPNALAVHLLQAPFSPPPSP-------PVQAPFSP---PASPPVSPS 688
Query: 1198 KKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSS 1257
P +A + P PL++ S P S + S T
Sbjct: 689 ATP----------PSQAPPSLAAP--PLQVPPSPP-------ASPPMSPSATPPPQAPPP 729
Query: 1258 LTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSV 1317
L ++ + P M R PPL A PPL P S P S+
Sbjct: 730 LAAPPLQ--VPPSPPASPPMSPSATPP--------PRVPPLLAA---PPLQVPPSPPASL 776
Query: 1318 PARGL-QPQPPATPAVPHPP----PSGAFGLGGALEAAESEGLGLG-CPSPCKRLDEELK 1371
P L +P P A PA+ PP PS G + S L + +P + L
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Query: 1372 RNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP 1431
L +P S + A PP GP DTS GP L A A P
Sbjct: 837 APLLQVPP---------------SPPASPTLQAPRRPPTPGP-DTSV-SGPRLTLALA-P 878
Query: 1432 GPPPLPGL-PSANSNGTPEPPLLEEKPPPTPPPAPT------PQPQPPPPPPPP------ 1478
GPPP P PS+ +G P L T P P+ PPP
Sbjct: 879 GPPPPPSRSPSSTLSG---PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 1479 QPAL----PSPPPLVAPTPSSPPP-PPLPPP--------------PPPAMPSP---PPPP 1516
PA P+PP P +P P PP P P A P+P P P
Sbjct: 936 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995
Query: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAA--------VCGETDEEAGES 1568
P + A A S P+ L L Q + + + AG S
Sbjct: 996 SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 1055
Query: 1569 GG 1570
GG
Sbjct: 1056 GG 1057
Score = 90.9 bits (224), Expect = 1e-17
Identities = 233/1044 (22%), Positives = 327/1044 (31%), Gaps = 201/1044 (19%)
Query: 58 SYATNHHPAGLSGLF----DTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQF 113
S T P G GL +T + P S ++ + ++ GP PG + ++ +
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 114 RSPSWQTAMHTPGPT----------ELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP 163
R+ + + P P+ +S A S+T PS +A + P++ G P
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP---AARRRPSAGGGLQRP 237
Query: 164 VPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLA----------GGGV 213
SLS P S PA P + P+ P G + L
Sbjct: 238 ASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 214 LGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNL-------LASSSAAAAAAEQSSPQLY 266
LGP P TP P PPP + T LA+ A + + P L
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 267 NFSGAAPGPP---------PPERALPRQDTV----IKHYQRPASAQPPPPPPPAHALQHY 313
PP PP +A P T+ + H S Q PP P +LQ
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 314 LSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGA 373
S G H + L SP + + T+ + +T P++
Sbjct: 416 TSLGSPTLQATH-SFLTMSP--------------RQTQASLTSPSRPASTPPDS------ 454
Query: 374 GGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS 433
P +Q+P PP +++ +P L P + S
Sbjct: 455 --------PPLQAP-------------LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 434 GAGGAGGQA------YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGP- 486
QA P + Q L P + L PS + P Q S P
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 487 PPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGG 546
P L T +P LQ + P P++ + P A P+L+ SP L G
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-----SPPLQGLPS 608
Query: 547 GWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVG-----SPGAPGKYLSSVLASAPFLA 601
+A P + PLQ+PP+ P + SP AP L+ L APF
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAPFSP 667
Query: 602 PPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
PP A + S ++ PP++ L PSPP +
Sbjct: 668 PPSPPVQAPFS------PPASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPS 719
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELG 721
A PP +P P + + A+L
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-- 777
Query: 722 LGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGL 781
+ K P + P LAT LQ P PP +P
Sbjct: 778 ---MSPLAKPPP---QAPPALATPP-------------LQALPSPPASFPGQAPFSPSAS 818
Query: 782 LLEAGGPDLPLVLPPP--PPQLLPSVLSHAPSPSPSASKVGVH---LLEPATRDGAPQ-- 834
L P PL PPP PP L +L PSP S + P T P+
Sbjct: 819 L-----PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873
Query: 835 ----PPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890
P PPPPP P L H + LR +S
Sbjct: 874 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS----------------- 916
Query: 891 PPAPGDTGVGPPNSE--GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFP 948
P G PP++E PA R P+P A R P + +P +
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAP--PLAFRGAPGAPLPWPPAT---------- 964
Query: 949 TMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGL 1008
G G+AD G E EG A P P A DP GP PG + G G
Sbjct: 965 ------GPGSAD--GLCTIYETEGPESA----TPAPGALDP-GP-SPGTSGGKAAAGAGA 1010
Query: 1009 GLDPNKPPELPSTVNAEPLGLIQS 1032
G P + + + PLG +Q+
Sbjct: 1011 GASSRSPKQ--ARLGELPLGALQA 1032
Score = 89.0 bits (219), Expect = 4e-17
Identities = 220/906 (24%), Positives = 279/906 (30%), Gaps = 186/906 (20%)
Query: 93 SALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQ 152
S ++R P +A++ L PS A TP P A P T PS A Q
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLA--TPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
Query: 153 HPASFGSRPFPVPSSLSLQDP---PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLA 209
P S + P P SL P P S + L +P L L QA T S +
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 210 GGGVLGPAGLGPAQTPPYRPG--PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSP---- 263
+ P + T P RP PPD PP L + +S + A + SSP
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487
Query: 264 ---QLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSY 320
L + + +P P +P +T + P S Q PP
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLET--QSSLAPPSLQTPP------------------ 527
Query: 321 PSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGY 380
A+L PL PS A P TA A
Sbjct: 528 ------ASLTTPPL--------ENLPSLAPPPLQTASAPLTT------------------ 555
Query: 381 RPIIQSPGYKTGKGGYGAAAGGATRPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGA 438
P +++P A T PPP P S ATP Q+ A+ G S
Sbjct: 556 -PHLETPPCPA-PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS----- 608
Query: 439 GGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYS 498
P P PQA L+ P + PP PP+ PP LAT +
Sbjct: 609 -----PPLSPLATPPPQA---------PPXLALPPLQA--PPSPPASPPLSPLATPSPQA 652
Query: 499 PDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGE 558
P+ L L P P P + P ASP +S S P S +
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-------------PPS-----Q 694
Query: 559 ASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK 618
A PS PLQ PP+ P + P LA+ P PP
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP------------- 741
Query: 619 GDGSELLAGPGGPPAERTEDEEFLIQHLLQAP------SPPRTSGADGLVGEDGAADASK 672
P PP + + LL AP SPP + L
Sbjct: 742 ---------PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL----------- 781
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP 732
A PP P LA LQ++ AS A + L P
Sbjct: 782 -------AKPPPQAPPALATPP-----LQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 733 ERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPL 792
+ P LA ++ + LQ PP P ++ P L A G
Sbjct: 830 Q----APPVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG----- 879
Query: 793 VLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEA 852
PPPPP PS P + +S E D P+ PPP
Sbjct: 880 --PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937
Query: 853 HLRSHGLEP-----AAPSPRLRPEESLDPPGAMQELLGAL-----EPLPPAPG--DTGVG 900
S G P AP L P PG+ L E PAPG D G
Sbjct: 938 AAWSRGPAPPLAFRGAPGAPL-PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 996
Query: 901 PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQD-EERSFFPTMEEMFGGGAA 959
P S GK AGA S + K R L S++Q R+ E GG+
Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 1056
Query: 960 DDYGKA 965
G A
Sbjct: 1057 GGPGGA 1062
Score = 82.0 bits (201), Expect = 5e-15
Identities = 127/463 (27%), Positives = 155/463 (33%), Gaps = 97/463 (20%)
Query: 1106 DKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRR-------GRK 1158
DKA A R R P L++ RP SP PP P R GRK
Sbjct: 6 DKAKAGAAARTPAARAPGLLTP---RPPGSPR------PPPPVTPAALRVLGAAGAVGRK 56
Query: 1159 PTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTR 1218
P A+R G P P PT + S+ P R GRG +A A T
Sbjct: 57 PL-AERAGGIGGATIPESAPRAGPTRSAGTSSRNPAS-----RPPASGRGERAPPAKNTS 110
Query: 1219 LEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMK 1278
P+ +S G A T L R E + + + +
Sbjct: 111 PGPV-----------------SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 153
Query: 1279 SGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP-PATPAVPHPPP 1337
S L +G R +G TP P S A P PA A P PP
Sbjct: 154 SA--------LSAGARRDT---SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 1338 SGAF-GLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQE 1396
G + A E + +E PSP R L+ R
Sbjct: 203 EGPRKSVSSASEHSTTE------PSPAARRRPSAGGGLQ----------------RPASR 240
Query: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEK 1456
S+SS+ + L P +GP TP P A P P GL + PP +
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAP------AHPSQPKPKGLQALR------PP---QV 285
Query: 1457 PPPTPPPAPTPQPQPPPPPPPPQP----ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
PP AP P P P P A P PPP A TP P LPP PP A P P
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL---PATLPPSPPLATPLP 342
Query: 1513 PPPPPPAAAP-LAAPPEEPAAPSPEDPELPDTRPLHLAKKQET 1554
PP P+A P L P PA P + P T P+ +T
Sbjct: 343 LAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Score = 78.6 bits (192), Expect = 6e-14
Identities = 172/698 (24%), Positives = 229/698 (32%), Gaps = 148/698 (21%)
Query: 38 SHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISA-LE 96
S P + L A PL S T H LS L S P A + +LI LE
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL--------ASHSPQAPLSSLIMPPLE 513
Query: 97 SRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGAL--PGSSTFPSSSALSAYQHP 154
++ PS + + +P + P S L P T P + P
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 155 ASFGSRPFPVPSSLSL---QDPPF--SPPANGLLSPH-DVLHLKPSQAPTVPSSLGFERL 208
+ + P PSS++ Q PP SPP GL SP L P QAP
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX--------- 624
Query: 209 AGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLY-N 267
L P Q PP P P P P N LA A + SP +
Sbjct: 625 --------LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676
Query: 268 FSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRA 327
FS A P P P Q P+ A PP PP+ +S + P
Sbjct: 677 FSPPASPPVSPSATPPSQ-------APPSLAAPPLQVPPSPPASPPMSPSATPPPQA--- 726
Query: 328 NLACSPLGGGEPSPGAGEPSKAGPS-GATAGASGRATGPEAAGGGGAGGGGGGYRPIIQS 386
P P A P + PS A+ S AT P P++ +
Sbjct: 727 -----------PPPLAAPPLQVPPSPPASPPMSPSATPPPRV------------PPLLAA 763
Query: 387 PGYKTGKGGYGAAAGGATRPPPPR---STATPKCQSLGGPAAAYATGKASGAGGAGGQAY 443
P + + PPP+ + ATP Q+L P A++ G A
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF-----PGQAPFSPSAS 818
Query: 444 SPGQPQGLLGPQA-------YGQGFGGGQAQDLSKAP----------SYSG--------- 477
P P PQA Q A +AP S SG
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 478 GPPQPP--------SGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASP 529
GPP PP SGP G ++ + +P++L+G G +G P ++ L P
Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE-LAACHP 937
Query: 530 SLSYSTGHSPALSGHGG-----GWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPG 584
+ ++S G +P L+ G W P++ G G A I + P + PG PG
Sbjct: 938 A-AWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 585 APGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQ 644
PG A AG G S A G P + ++Q
Sbjct: 995 ----------------PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQAS--VVQ 1036
Query: 645 HLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGG 682
HLL + A+G G G GG GGA G
Sbjct: 1037 HLLSRTL--LLAAAEGAAGGSG--------GGPGGAEG 1064
Score = 78.2 bits (191), Expect = 8e-14
Identities = 178/678 (26%), Positives = 233/678 (34%), Gaps = 150/678 (22%)
Query: 54 HPLQSYAT--NHHP-AGLSGLFDTGLHHAGSAGPD------ASVMNL-ISALESRGPQPG 103
HPLQ+ ++ +H P A LS L L S P AS+ + L S P P
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 104 PSASSLLSQFRSPSWQTA-MHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPF 162
+AS+ L+ +P +T P P + S PSS A Q P + S P
Sbjct: 547 QTASAPLT---TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 163 PVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAP-TVPSSLGFERLAGGGVLGPAGLG- 220
L PP SP A L L P QAP + P+S LA P L
Sbjct: 604 Q-----GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658
Query: 221 -----PAQTPPYRP-----GPPDPPP------PPRHLPTQFNLLASSSAAAAAAEQSSPQ 264
P PP P PP PP PP P LA+ + +SP
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---LAAPPLQVPPSPPASPP 715
Query: 265 LYNFSGAAPGPPPPERALPRQDTVIKHYQRPAS--AQPPPPPPPAHALQHYLSCGGSYPS 322
+ + P PPP A P Q P S A PPP PP A L S P
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP-LQVPPSPP- 773
Query: 323 MGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRP 382
A+L SPL A P +A P+ AT + P + G + P
Sbjct: 774 ----ASLPMSPL--------AKPPPQAPPALATPPLQALPSPPASFPGQAP------FSP 815
Query: 383 IIQSPGYKTGKGGYGAAAGGATRPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGAGG 440
P PPP P A P Q P A S A
Sbjct: 816 SASLP------------MSPLATPPPQAPPVLAAPLLQVPPSPPA-------SPTLQAPR 856
Query: 441 QAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS--------GPPPPGLA 492
+ +PG + GP+ L+ AP GPP PPS GP G +
Sbjct: 857 RPPTPGPDTSVSGPRL-----------TLALAP----GPPPPPSRSPSSTLSGPDLAGHS 901
Query: 493 TCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGG----- 547
+ + +P++L+G G +G P ++ L P+ ++S G +P L+ G
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAE-LAACHPA-AWSRGPAPPLAFRGAPGAPLP 959
Query: 548 WGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGS 607
W P++ G G A I + P + PG PG PG
Sbjct: 960 WPPAT--GPGSADGLCTIYETEGPESATPAPGALDPGPS----------------PGTSG 1001
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA 667
A AG G S A G P + ++QHLL S L +GA
Sbjct: 1002 GKAAAGAGAGASSRSPKQARLGELPLGALQAS--VVQHLL--------SRTLLLAAAEGA 1051
Query: 668 ADASKGLGGSGGAGGPPG 685
A GG+GG PG
Sbjct: 1052 A---------GGSGGGPG 1060
Score = 52.4 bits (124), Expect = 5e-06
Identities = 94/336 (27%), Positives = 124/336 (36%), Gaps = 55/336 (16%)
Query: 81 SAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQT--AMHTPGPTELFIS--GAL 136
SA P V L++A + P P P AS +S P Q A+ TP P + S +
Sbjct: 750 SATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATP-PLQALPSPPASF 807
Query: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS------------ 184
PG + F S++L P PV ++ LQ PP SPPA+ L
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAP-PVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDT 865
Query: 185 ----PHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG---PAQTPPYRPGPPD---- 233
P L L P P PS L+G + G + P + Y GP
Sbjct: 866 SVSGPRLTLALAPGPPPP-PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
Query: 234 PPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQ 293
PPP L A+ AA + + P + + AP P PP D + Y+
Sbjct: 925 SPPPDAEL-------AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 977
Query: 294 R--PASAQPPP---PPPPAHALQHYLSCGGSYPSMGHR----ANLACSPLGGGEPSPGAG 344
P SA P P P P+ + G+ R A L PLG + S
Sbjct: 978 TEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQH 1037
Query: 345 EPSK----AGPSGATAGASGRATGPEAAGGGGAGGG 376
S+ A GA G+ G GP A GGG GG
Sbjct: 1038 LLSRTLLLAAAEGAAGGSGG---GPGGAEGGGVTGG 1070
Score = 45.1 bits (105), Expect = 7e-04
Identities = 93/370 (25%), Positives = 122/370 (32%), Gaps = 79/370 (21%)
Query: 1490 APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL----AAPPEEPAAPSPEDPELPDTRP 1545
A TP++ P L P PP + P PPPP PAA + A +P A
Sbjct: 14 ARTPAARAPGLLTPRPPGS-PRPPPPVTPAALRVLGAAGAVGRKPLA------------- 59
Query: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQT-GREPPPIW 1604
E AG GG I E RA S + + PP
Sbjct: 60 -----------------ERAGGIGGATI----PESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 1605 RVQKALLQKFT---PEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRV 1661
R ++A K T P G+ LG G + + + K+ +
Sbjct: 99 RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 158
Query: 1662 CARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPET--PEKTTSEKPPEQTP 1719
AR+ P A+ +AG P AP+ P+P T P K+ S T
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 1720 ETAMPEPPAPEKPS----LLRPVEKEKEKEKVTRGERPLRGERATSGRQTR--PERSLAT 1773
E P P A +PS L RP + ++ PL A SG R P
Sbjct: 219 E---PSPAARRRPSAGGGLQRPASR-----SLSSSATPL-SSPARSGPSARGTPRAPAHP 269
Query: 1774 GQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPG------ 1827
QP L RP +V PP+K +A GP SS + SP
Sbjct: 270 SQPKPKGLQALRPPQV---TPPRK----------DAAPALGPLSSSPLATPSPSGTKARP 316
Query: 1828 APSEDERAVP 1837
P D A P
Sbjct: 317 VPPPDNAATP 326
Score = 43.9 bits (102), Expect = 0.002
Identities = 47/186 (25%), Positives = 69/186 (37%), Gaps = 27/186 (14%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAP---------APPPKPETPEKTTSEKPPEQTP- 1719
PP+ V S A P+S S+ PPP+AP PP P +P + S PP + P
Sbjct: 702 PPLQVPPSPPASPPMSP--SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Query: 1720 ---ETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLR----------GERATSGRQTR 1766
+ PP+P + P+ K + PL+ G+ S +
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819
Query: 1767 PERSLATGQPATSRLPKARPTKVKAEPP--PKKRKKWLKEAGGNATAGGGPPGSSSDSES 1824
P LAT P + A +V PP P + G T+ GP + + +
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
Query: 1825 SPGAPS 1830
P PS
Sbjct: 880 PPPPPS 885
Score = 37.7 bits (86), Expect = 0.12
Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 20/86 (23%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAP---------APPPKPETPEKTTSEKPPEQTPE 1720
PPV S A PVS S+ PP +AP PP P +P + S PP Q P
Sbjct: 671 PPVQAPFSPPASPPVSP--SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 1721 -------TAMPEPPA--PEKPSLLRP 1737
P PPA P PS P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 36.2 bits (82), Expect = 0.34
Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 10/79 (12%)
Query: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP---APPPK---PETPEKTTSEKPPEQTP 1719
P PP P+ P + + PPP+AP A PP P P + PP+ P
Sbjct: 568 PLQAPPSPLT----TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
Query: 1720 ETAMPEPPAPEKPSLLRPV 1738
A+P AP P P+
Sbjct: 624 XLALPPLQAPPSPPASPPL 642
Score = 35.8 bits (81), Expect = 0.44
Identities = 33/128 (25%), Positives = 46/128 (35%), Gaps = 6/128 (4%)
Query: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPET----AMPEP 1726
P P + A + + A S P P AP P +P + S PP Q P + + P
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 1727 PAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARP 1786
P+P + P + PL + S + P AT P L A P
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPL--QVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 1787 TKVKAEPP 1794
+V PP
Sbjct: 766 LQVPPSPP 773
Score = 34.7 bits (78), Expect = 0.98
Identities = 35/133 (26%), Positives = 41/133 (30%), Gaps = 13/133 (9%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP-----KPETPEKTTSEKPPEQTPETAMP 1724
P P+ PV A PP PA P +P TP TS P T A
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
Query: 1725 EPPAPEK--PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP 1782
PP P + S L + T LR G + PE A P + L
Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR------GYDSGPEGGAAASPPPDAELA 933
Query: 1783 KARPTKVKAEPPP 1795
P P P
Sbjct: 934 ACHPAAWSRGPAP 946
Score = 34.3 bits (77), Expect = 1.3
Identities = 59/272 (21%), Positives = 93/272 (34%), Gaps = 33/272 (12%)
Query: 1669 RPPV---PVRRSGQAKNPVSAGGSSAPPPKA----PAPPP-KPETP-EKTTSEKPPEQTP 1719
RPP P + + A P+S+ + P P P PPP TP T PP TP
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
Query: 1720 -ETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQ--P 1776
A P P AP PSL + L AT Q P + Q P
Sbjct: 341 LPLAPPSPSAP--PSL-----------------QTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 1777 ATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAV 1836
+ +P + P + L + AT G P + +P + + ++
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 1837 --PGRLLKTRAMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKK 1894
P R T ++ + + S L + A+ L + P++ + L + +
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 1895 KVLKRLSLSPALQDALHTFPQLQVEQSGEGSP 1926
L L + P + P LQ + +P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Score = 33.1 bits (74), Expect = 2.8
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 7/59 (11%)
Query: 1680 AKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPET-AMPEPPAPEKPSLLRP 1737
A P++ PP AP P P +P T PP +TP + A P P AP P+L P
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTT----PPPETPSSIATPPPQAP--PALASP 601
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 130 bits (326), Expect = 2e-29
Identities = 264/1034 (25%), Positives = 325/1034 (31%), Gaps = 164/1034 (15%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GP G P PGPP PP PP P A+ A + QL G
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGP-PGLGGNFAAQMAGGFDEKAGGAQL----GV 198
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
GP P + PP P A Q + G G
Sbjct: 199 MQGP-----------------MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-----VS 236
Query: 332 SPLGGGEPSPGAGEPSKAGPSGATAGASGRAT-GPEAAGGGGAGGGGGGYRPIIQSPGYK 390
P+G P G+P G +G A R GP+ A G G G + PG
Sbjct: 237 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD 296
Query: 391 TGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAY-SPGQPQ 449
KG GA P + + G P TG A AG G P P
Sbjct: 297 GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP 356
Query: 450 GLLGPQAYGQGFGG-----GQAQDL-SKAPSYSGGPPQPPSGPPPPGLATCQSY-SPDQL 502
G +GP A G GF G G+A ++ P + GP P P PG A D +
Sbjct: 357 GPVGP-AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI 415
Query: 503 QGQ-----LYGVQGEP-YPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGG 556
G G+ G P +PGP P P ++G G GP G
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK--GEP 473
Query: 557 GEASPSHIIRPLQSPP---ATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG 613
G A P P A G P GVG G PG+ GA
Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE---------------------RGAP 512
Query: 614 GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQ---APSPPRTSGADGLVGEDGAADA 670
G +G G + LAGP G P ER + P P GA GL G G A
Sbjct: 513 GNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571
Query: 671 SKGLGGSGGAG-----GPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRL 725
+G SG G GPPG + A+ P + + L G
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGP--QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629
Query: 726 KEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEA 785
K E G P G A G + Q P PP P + +P G+ EA
Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689
Query: 786 GGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD-----GAPQPPPPPP 840
G P L + P + P SP A + P T GA P PP
Sbjct: 690 GAPGL---VGPRGERGFPGERG-----SPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 741
Query: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE-----LLGALEPLPPAP- 894
PP + + G+ A P P GA + L G + P PA
Sbjct: 742 AQGPPGLQGMPGERGAAGI--AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799
Query: 895 -GDTG-VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEE 952
G+ G VGPP G AGA +P +G P P
Sbjct: 800 NGEKGEVGPPGPAGS--AGARGAPGERGETGP-----------------------PGPAG 834
Query: 953 MFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDP 1012
G AD A + E K AG P GP P A G T G
Sbjct: 835 FAGPPGADGQPGAKGEQGEAGQKGDAGAP---------GPQGPSGAPGPQGPTGVTGPKG 885
Query: 1013 NKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKL 1072
+ + P P + GP + P PP PP P+ PKG
Sbjct: 886 ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-------------- 931
Query: 1073 LKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRP 1132
+ S R +P Q P E E D P+ P P ++ R
Sbjct: 932 -RGDSGPPGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG--PQGLAGQRGIV 983
Query: 1133 AL-SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIR-PLEVPTTAGPASA 1190
L G+ F P PGP G + P + GPP P G P + P P G A
Sbjct: 984 GLPGQRGERGF-PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGA 1042
Query: 1191 STP--TDGAKKPRG 1202
P DGA +G
Sbjct: 1043 DGPPGRDGAAGVKG 1056
Score = 125 bits (313), Expect = 6e-28
Identities = 267/972 (27%), Positives = 318/972 (32%), Gaps = 183/972 (18%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPT----VPSSLGFERLAGG-------GVLGPAGLGPA 222
P +P A G P + +Q P P S G +G G G AG
Sbjct: 368 PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427
Query: 223 QTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPP 277
P PGP PP P ++ + P + F G PGP
Sbjct: 428 AGAPGFPGPRGPPGPQ----------GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 477
Query: 278 PERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGG 337
P+ A K R P PP G + G+R L G
Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPP-----------GERGAPGNRGFPGQDGLAGP 526
Query: 338 EPSPGAGEPSK-AGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
+ +PG PS AGP GA G GR P G G G RP P K G G
Sbjct: 527 KGAPGERGPSGLAGPKGAN-GDPGRPGEPGLPGARGLTG-----RPGDAGPQGKVGPSGA 580
Query: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYAT-GKASGAG--GAGGQAYSPGQP--QGL 451
G P P + P GP A GKA G GA G PG+ G
Sbjct: 581 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 640
Query: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511
GP G G + + + PS G P PP P G Q + L G +G
Sbjct: 641 AGPPGPA-GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699
Query: 512 EP-YPG----PAAHSQGLPTASPSLSYSTGHSPAL--SGHGGGWGPSSLGG-GGEASPSH 563
E +PG P A P P + G A +G G GP L G GE +
Sbjct: 700 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 759
Query: 564 IIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK--GDG 621
I P G G GAPGK L + PPG AGA G KG+ G
Sbjct: 760 IAGPKGDRGDVGEK---GPEGAPGKDGGRGLTGP--IGPPGP----AGANGEKGEVGPPG 810
Query: 622 SELLAGPGGPPAERTEDEEFLIQHLLQAPS----PPRTSGADGLVGEDGAADASKGLGGS 677
AG G P ER E P+ PP G G GE G A KG G+
Sbjct: 811 PAGSAGARGAPGERGETGP-------PGPAGFAGPPGADGQPGAKGEQGEA-GQKGDAGA 862
Query: 678 GGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGE 737
G GP G P PQ T + +GA RG +
Sbjct: 863 PGPQGPSGAP------GPQG-------PTGVTGPKGA-------------------RGAQ 890
Query: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLE------AGGPDLP 791
P G AT GA + +P PP P S + P G + AG P L
Sbjct: 891 GPPG-ATGFP--GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947
Query: 792 LVLPPP-----PPQLLPSVLSHAPSPSPSASKVGVHLL-----------------EPATR 829
PP P PS P P A + G+ L EP +
Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG-K 1006
Query: 830 DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE--PAAPSPRLRPEESLDPPGAMQELLGAL 887
GAP PP P P L G E P A P R + + G E
Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVG 1065
Query: 888 EP-LPPAPGDTG-VGPPNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
P P PG G GP +G + AGA P G R I P D+
Sbjct: 1066 APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR-----GIQGPQGPRGDKGE 1120
Query: 945 SFFPTMEEMFGG-GAADDYGKAGPPEDEGDPKAG--AGP--PPGPPAYDPYGPYCPGRAS 999
+ P + G G G GPP GD A AGP P GPP P GP A+
Sbjct: 1121 AGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG--PVGPSGKDGAN 1178
Query: 1000 GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGL 1059
G PG P PP P G +SG + P PP P PP P P G+
Sbjct: 1179 GI----PG----PIGPPG--------PRG--RSG--ETGPAGPPGNPGPPGPPGPPGPGI 1218
Query: 1060 TSPIFCSTKPKK 1071
F P++
Sbjct: 1219 DMSAFAGLGPRE 1230
Score = 120 bits (300), Expect = 2e-26
Identities = 329/1304 (25%), Positives = 404/1304 (30%), Gaps = 204/1304 (15%)
Query: 331 CSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYK 390
C P+ + + +G+P G G G GP+ G G G R G K
Sbjct: 85 CCPICPTDLATASGQPGPKGQKGEP-GDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEK 143
Query: 391 TGKG--GYGAAAGGATRPPPPRSTATPKCQSLGGP-AAAYATGKASGAGGAG-GQAYSPG 446
G G G P PP P LGG AA A G AGGA G P
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203
Query: 447 QPQGLLGPQAYG-----QGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQ 501
P G GP QGF G + S GP PP P PG D
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG---------DD 254
Query: 502 LQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHS--PALSGHGGGWGPSSL----GG 555
+ G GE P ++G P +P L GH P L G G G + G
Sbjct: 255 GEAGKPGKAGERGPPGPQGARGFP-GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313
Query: 556 GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGY 615
GE + P P GR G+ GA G A P P G GA G
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373
Query: 616 KGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLG 675
KG+ G GP G R E P P +GA G G DG A KG
Sbjct: 374 KGEA-GPTGARGPEGAQGPRGEPG---------TPGSPGPAGASGNPGTDGIPGA-KGSA 422
Query: 676 GSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP--E 733
G+ G G PG P PQ T +G T E G+ K ++ GP E
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQG-------ATGPLGPKGQTG--EPGIAGFKGEQ-GPKGE 472
Query: 734 RGGETPEGLATSVVHYGA-GAKELGAFLQKSPPPPPPTAQSTQ--PTPHGLLLEAGGPD- 789
G P+G G GA+ + PP A + P GL G P
Sbjct: 473 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532
Query: 790 ---LPLVLPP--------PPPQLLPSV--LSHAPSPSPSASKVGVHLLEPATRDGAPQPP 836
L P P LP L+ P + KVG GAP
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP--------SGAPGED 584
Query: 837 PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGD 896
P PP P + G + A P E+ L PGA L LP G+
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL--PGAP-----GLRGLPGKDGE 637
Query: 897 TGV-GPPNSEGK----------DPAGAYRSPSPQGTKAPRFVP----LTSICFPDSLLQD 941
TG GPP G P+G P P G P + L+
Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 697
Query: 942 EERSFFPTMEEMFGG-GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYG----PYCPG 996
FP G G G G P +G PK +GP P A P G P G
Sbjct: 698 RGERGFPGERGSPGAQGLQGPRGLPGTPGTDG-PKGASGPAGPPGAQGPPGLQGMPGERG 756
Query: 997 RASGAGPETPGLGLDPNKPPELPSTVNAE----PLGLIQSGPHQAAPPPPPPPPPPPAPA 1052
A AGP+ + P P P+G GP A PP PA +
Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG--PPGPAGANGEKGEVGPPGPAGS 814
Query: 1053 SEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPA 1112
+ +G P + +T PP + A+ + EA + K D A
Sbjct: 815 AGARGA----------PGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ-KGDAGA 862
Query: 1113 DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP--GPDGPRRRGRKPTKAKRDGPPRP 1170
P P P G P G GP P A R GPP
Sbjct: 863 PGPQGPSGAP------------GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910
Query: 1171 RGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLS 1230
G P P GP+ DG K RG GR E L
Sbjct: 911 NGNPG-----PPGPPGPSGK----DGPKGARGDSGPPGRAGEPG--------------LQ 947
Query: 1231 VPKAGEG-LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFL 1289
P G G D SG + L ++ I + ++ E GF
Sbjct: 948 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQRGER--GFPGLPGPSG 1002
Query: 1290 KSGKRHPPLYQAGLTPPLSPPKSV-PPSVPARGLQPQPPATPAVPHPPP-SGAFGLGGAL 1347
+ GK+ P G + PP V PP + +P +P PP GA G+ G
Sbjct: 1003 EPGKQGAP----GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG-- 1056
Query: 1348 EAAESEGLGL-GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALD 1406
+ E+ +G G P P S K D E+ +
Sbjct: 1057 DRGETGAVGAPGAPGP----------------PGSPGPAGPTGKQGDRGEAGAQGPMGPS 1100
Query: 1407 DPPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPA 1464
P AG + P GP A PG L G G P PP + P
Sbjct: 1101 GP--AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1158
Query: 1465 PTPQPQPPPPPPPPQP----ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAA 1520
P+ PP P P +P P P S P PP P P PP PP P
Sbjct: 1159 PSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGI 1218
Query: 1521 APLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEE 1564
A P P+ PL + + A + D E
Sbjct: 1219 DMSAFAGLGPREKGPD--------PLQYMRADQAAGGLRQHDAE 1254
Score = 119 bits (299), Expect = 2e-26
Identities = 319/1253 (25%), Positives = 395/1253 (31%), Gaps = 318/1253 (25%)
Query: 204 GFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSP 263
GF+ AGG LG P P P PP P P E P
Sbjct: 186 GFDEKAGGAQLG------VMQGPMGPMGPRGPPGPAGAP------GPQGFQGNPGEPGEP 233
Query: 264 QLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSM 323
+ G P PP + P D +P A PP P A + + G
Sbjct: 234 GVSGPMGPRGPPGPPGK--PGDDG---EAGKPGKAGERGPPGPQGA-RGFPGTPGLPGVK 287
Query: 324 GHRA-----------------NLACSPLGGGEPSPGA-----GEPSKAGPSGATAGASGR 361
GHR + SP G P P GE + GP+GA AGA G
Sbjct: 288 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA-AGARGN 346
Query: 362 ATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG 421
P AG G G GG PG+ G G A R P + + G
Sbjct: 347 DGQPGPAGPPGPVGPAGG-------PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399
Query: 422 GPAAAYATGK--------ASGAGGAGGQAYSPG--------QPQGLLGP-----QAYGQG 460
P A A+G A G+ GA G A +PG PQG GP Q G
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459
Query: 461 FGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQ--GEPYPGPA 518
G + + + P GP P P P G +G+ GV G P A
Sbjct: 460 IAGFKGE---QGPKGEPGPAGPQGAPGPAG-----EEGKRGARGEPGGVGPIGPPGERGA 511
Query: 519 AHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGG-------------------GEA 559
++G P L+ G +P G G GP G G+A
Sbjct: 512 PGNRGFP-GQDGLAGPKG-APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569
Query: 560 SPSHIIRPLQSPPATGRP-----------PGV-------GSPGAPGKYLSSVLASAPFL- 600
P + P +P GRP PGV G+ G PGK L AP L
Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 629
Query: 601 ------------APPGAGSYAAGAGGYKGKG-DGSELLAGPGGPPAERTEDEEFLIQHLL 647
PPG A G G G + L GP GPP E + + +
Sbjct: 630 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689
Query: 648 QAPSPPRTSGADGLVGEDGAADA-----------SKGLGGSGGAGGPPGTPYELAKEDPQ 696
AP G G GE G+ A + G G GA GP G P + P
Sbjct: 690 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP---GAQGPP 746
Query: 697 RYHLQSVIRTSASL-----------DEGATAALELGLGRLKEKKKGP--------ERGGE 737
R +A + ++G A GR GP E+G
Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806
Query: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPP-----PTAQSTQPTPHGLLLEAG------ 786
P G A S AGA+ ++ PP P P QP G EAG
Sbjct: 807 GPPGPAGS-----AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861
Query: 787 --GPDLPLVLPPP--PPQLL-PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP 841
GP P P P P + P A P + G A R G P P P
Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGA-----AGRVGPPGSNGNPGP 916
Query: 842 PPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
P PP P + + G PPG E G P P PG+ G
Sbjct: 917 PGPPGPSGKDGPKGARG--------------DSGPPGRAGE-PGLQGPAGP-PGEK--GE 958
Query: 902 PNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
P +G P+GA P PQG R + + P Q ER FP + G + +
Sbjct: 959 PGDDG--PSGAEGPPGPQGLAGQRGI----VGLPG---QRGERG-FPGLP-----GPSGE 1003
Query: 962 YGKAGPPEDEGD--PKAGAGPP-----------PGPPAYDPYGPYCPGRASGAG-----P 1003
GK G P GD P GPP G P D GP PGR AG
Sbjct: 1004 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD--GP--PGRDGAAGVKGDRG 1059
Query: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPI 1063
ET +G P P S A P G + G A P P PA A G+ P
Sbjct: 1060 ETGAVGA-PGAPGPPGSPGPAGPTG--KQGDRGEAGAQGPMGPSGPAGAR----GIQGP- 1111
Query: 1064 FCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR--- 1120
Q P+ D+ +A P + L R
Sbjct: 1112 -------------------------QGPR----------GDKGEAGEPGERGLKGHRGFT 1136
Query: 1121 ----LPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRP-R 1175
LP + A P G P PGP GP + GPP PRGR
Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGP-PGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1195
Query: 1176 IRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAG 1235
P P GP P G G A G R + PL+ + AG
Sbjct: 1196 TGPAGPPGNPGPPGPPGPP---------GPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1246
Query: 1236 EGLGTSSGDAISGTDHNSLDSSL--------TREKIEAKIKEVEEKQPEMKSG 1280
G DA SL++ + +R+ ++++ PE KSG
Sbjct: 1247 ---GLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSG 1296
Score = 64.7 bits (156), Expect = 9e-10
Identities = 270/1152 (23%), Positives = 346/1152 (30%), Gaps = 251/1152 (21%)
Query: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELL 884
EP T G P PP PP PP PP A + G + A +L G MQ +
Sbjct: 154 EPGT-PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL---------GVMQGPM 203
Query: 885 GALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
G + P P PG G P +P G P G PR P P D+
Sbjct: 204 GPMGPRGP-PGPAGAPGPQGFQGNP-GEPGEPGVSGPMGPRGPP-----GPPGKPGDDGE 256
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
+ P G A + G GP G P G PG + Y P G AG
Sbjct: 257 AGKP--------GKAGERGPPGPQGARGFP--GTPGLPGVKGHRGY-PGLDGAKGEAG-- 303
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLI----QSGPHQAAPPPPPPPPPPPAPASEPKGGLT 1060
PG+ + P E S P GL ++GP AA P PA P G
Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363
Query: 1061 SPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR 1120
P F K P AQ E + PA NP
Sbjct: 364 GPGFPGAPGAK-----------GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT 412
Query: 1121 --LPDLVSSCRSRPALS-------PLGDIDFCPPNP----GPDGPRRRGRKPTKAKRDGP 1167
+P S + P ++ P G PP P GP GP+ + +P A G
Sbjct: 413 DGIPGAKGSAGA-PGIAGAPGFPGPRG-----PPGPQGATGPLGPKGQTGEPGIAGFKGE 466
Query: 1168 PRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLK---P 1224
P+G P AGP A P K RG G G R P P
Sbjct: 467 QGPKGEPG--------PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518
Query: 1225 LKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREK----IEAKIKEVEEKQPEMKSG 1280
+ L+ PK G SG ++G + D E + P+ K G
Sbjct: 519 GQDGLAGPKGAPGERGPSG--LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576
Query: 1281 FMASFLDFLKSGKRHPPLYQ----------------AGLTPPLSPPKSVPPSVPARGLQP 1324
+ + G+ PP Q A P + K +P + RGL
Sbjct: 577 PSGAPGE---DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 633
Query: 1325 QPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSS-- 1382
+ T A P P+G G G A G G P P E K + +P +
Sbjct: 634 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ-GLPGPPGPPGEGGKPGDQGVPGEAGAP 692
Query: 1383 -------DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPP 1435
+ + + + P GPK S P GPP A GPP
Sbjct: 693 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-----GPPG 747
Query: 1436 LPGLPSANSNGTPEPPL-----LEEKPP--------------PTPPPAPT----PQPQPP 1472
L G+P P + EK P P PP P + +
Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 807
Query: 1473 PPPP-----------------PPQPALPSPPPLV--------------------APTPSS 1495
PP P PP PA + PP AP P
Sbjct: 808 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 867
Query: 1496 PPPPPLPPPP-----PPAMPSPPPPPP----PAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
P P P P P PP P AA PP P P P P +
Sbjct: 868 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG 927
Query: 1547 HLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRV 1606
+ ++ AGE G +G E +D PS G E PP
Sbjct: 928 PKGARGDSGP-----PGRAGEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPP---- 971
Query: 1607 QKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKP 1666
P+ GQR G G R +R + +
Sbjct: 972 --------GPQGLAGQR---------GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 1014
Query: 1667 WHRPPVPVRR---SGQAKNPVSAG--GSSAPPPK-----------------APAPPPKPE 1704
PP PV +G A P G G+ PP + AP P P
Sbjct: 1015 DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1074
Query: 1705 TPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE-----KEKEKEKVTRGERPLRGERA 1759
+P E P P P+ R ++ + + E GER L+G R
Sbjct: 1075 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1134
Query: 1760 TSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGG-GPPGS 1818
+G Q P +G S A P+ + P P + G N G GPPG
Sbjct: 1135 FTGLQGLPGPPGPSGDQGAS--GPAGPSGPRGPPGPVGPS---GKDGANGIPGPIGPPGP 1189
Query: 1819 SSDS-ESSPGAP 1829
S E+ P P
Sbjct: 1190 RGRSGETGPAGP 1201
Score = 40.8 bits (94), Expect = 0.014
Identities = 135/532 (25%), Positives = 162/532 (30%), Gaps = 110/532 (20%)
Query: 1319 ARGLQPQP-PATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETL 1377
ARG QP PA P P P G G GA A+ E G P E +
Sbjct: 343 ARGNDGQPGPAGPPGPVGPAGGP-GFPGA-PGAKGEAGPTGARGP------EGAQGPRGE 394
Query: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP-GPPPL 1436
P + A + I A + P +AG P GPP A P GP
Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 454
Query: 1437 PGLPS-ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495
G P A G E+ P P PA PQ P P + P V P
Sbjct: 455 TGEPGIAGFKG-------EQGPKGEPGPAG-PQGAPGPAGEEGKRGARGEPGGVGPIG-- 504
Query: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS--------PEDPELPDTRPLH 1547
PP P P P AP P A P P +P LP R
Sbjct: 505 -PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG-- 561
Query: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPI---W 1604
L + A G+ G SG G + GR PP
Sbjct: 562 LTGRPGDAGPQGKV----GPSGAPG----------------------EDGRPGPPGPQGA 595
Query: 1605 RVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCAR 1664
R Q ++ P+ +G+ G G L + KD A
Sbjct: 596 RGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG-------------LRGLPGKDGETGAAG 642
Query: 1665 KPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP 1724
P P P G+ P +G P P P PP + KP +Q
Sbjct: 643 PPG--PAGPAGERGEQGAPGPSGFQGLPGP--PGPPGE--------GGKPGDQGV----- 685
Query: 1725 EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKA 1784
P P L+ P RGER GER + G Q G P T PK
Sbjct: 686 -PGEAGAPGLVGP-----------RGERGFPGERGSPGAQGLQGPRGLPGTPGTDG-PKG 732
Query: 1785 RPTKVKAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSD-SESSP-GAPSED 1832
A PP + L+ G A G GP G D E P GAP +D
Sbjct: 733 --ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782
Score = 33.9 bits (76), Expect = 1.7
Identities = 50/203 (24%), Positives = 63/203 (31%), Gaps = 32/203 (15%)
Query: 1393 DLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAA--------VPGP--PPLPGLPSA 1442
D+++ +S I + P+ P D +T G P + GP PP P P+
Sbjct: 71 DVKDCLSPEIPFGECCPIC-PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAG 129
Query: 1443 NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPL-----------VAP 1491
+ EK P P P P PP P P PP L
Sbjct: 130 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 189
Query: 1492 TPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP--LAAPPEEPAAPSPEDPELPDTRPLHLA 1549
+ P P P PP P A P P EP P P P P
Sbjct: 190 KAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249
Query: 1550 KKQETAAVCGETDEEAGESGGEG 1572
K + D EAG+ G G
Sbjct: 250 KPGD--------DGEAGKPGKAG 264
Score = 31.6 bits (70), Expect = 8.3
Identities = 42/180 (23%), Positives = 59/180 (32%), Gaps = 38/180 (21%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP-----------KPETPEKTTSEKPPEQT 1718
PP P +G P G + P P A PP + E +K + P Q
Sbjct: 808 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 867
Query: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPAT 1778
P A P P+ P+ G + RG + G P + G P +
Sbjct: 868 PSGA----PGPQGPT-------------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910
Query: 1779 SRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPG 1838
+ P PP K K A G++ GPPG + + A E+ PG
Sbjct: 911 NGNPG------PPGPPGPSGKDGPKGARGDS----GPPGRAGEPGLQGPAGPPGEKGEPG 960
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 130 bits (326), Expect = 2e-29
Identities = 264/1034 (25%), Positives = 325/1034 (31%), Gaps = 164/1034 (15%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GP G P PGPP PP PP P A+ A + QL G
Sbjct: 75 GAPGPRGRDGEPGTPGNPGPPGPPGPPGP-PGLGGNFAAQMAGGFDEKAGGAQL----GV 129
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
GP P + PP P A Q + G G
Sbjct: 130 MQGP-----------------MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG-----VS 167
Query: 332 SPLGGGEPSPGAGEPSKAGPSGATAGASGRAT-GPEAAGGGGAGGGGGGYRPIIQSPGYK 390
P+G P G+P G +G A R GP+ A G G G + PG
Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD 227
Query: 391 TGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAY-SPGQPQ 449
KG GA P + + G P TG A AG G P P
Sbjct: 228 GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPP 287
Query: 450 GLLGPQAYGQGFGG-----GQAQDL-SKAPSYSGGPPQPPSGPPPPGLATCQSY-SPDQL 502
G +GP A G GF G G+A ++ P + GP P P PG A D +
Sbjct: 288 GPVGP-AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI 346
Query: 503 QGQ-----LYGVQGEP-YPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGG 556
G G+ G P +PGP P P ++G G GP G
Sbjct: 347 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPK--GEP 404
Query: 557 GEASPSHIIRPLQSPP---ATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG 613
G A P P A G P GVG G PG+ GA
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGE---------------------RGAP 443
Query: 614 GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQ---APSPPRTSGADGLVGEDGAADA 670
G +G G + LAGP G P ER + P P GA GL G G A
Sbjct: 444 GNRGF-PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502
Query: 671 SKGLGGSGGAG-----GPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRL 725
+G SG G GPPG + A+ P + + L G
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGP--QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560
Query: 726 KEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEA 785
K E G P G A G + Q P PP P + +P G+ EA
Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620
Query: 786 GGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD-----GAPQPPPPPP 840
G P L + P + P SP A + P T GA P PP
Sbjct: 621 GAPGL---VGPRGERGFPGERG-----SPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPG 672
Query: 841 PPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQE-----LLGALEPLPPAP- 894
PP + + G+ A P P GA + L G + P PA
Sbjct: 673 AQGPPGLQGMPGERGAAGI--AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730
Query: 895 -GDTG-VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEE 952
G+ G VGPP G AGA +P +G P P
Sbjct: 731 NGEKGEVGPPGPAGS--AGARGAPGERGETGP-----------------------PGPAG 765
Query: 953 MFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDP 1012
G AD A + E K AG P GP P A G T G
Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAP---------GPQGPSGAPGPQGPTGVTGPKG 816
Query: 1013 NKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKL 1072
+ + P P + GP + P PP PP P+ PKG
Sbjct: 817 ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-------------- 862
Query: 1073 LKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRP 1132
+ S R +P Q P E E D P+ P P ++ R
Sbjct: 863 -RGDSGPPGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG--PQGLAGQRGIV 914
Query: 1133 AL-SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIR-PLEVPTTAGPASA 1190
L G+ F P PGP G + P + GPP P G P + P P G A
Sbjct: 915 GLPGQRGERGF-PGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGA 973
Query: 1191 STP--TDGAKKPRG 1202
P DGA +G
Sbjct: 974 DGPPGRDGAAGVKG 987
Score = 125 bits (313), Expect = 6e-28
Identities = 267/972 (27%), Positives = 318/972 (32%), Gaps = 183/972 (18%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPT----VPSSLGFERLAGG-------GVLGPAGLGPA 222
P +P A G P + +Q P P S G +G G G AG
Sbjct: 299 PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 358
Query: 223 QTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPP 277
P PGP PP P ++ + P + F G PGP
Sbjct: 359 AGAPGFPGPRGPPGPQ----------GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 408
Query: 278 PERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGG 337
P+ A K R P PP G + G+R L G
Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPP-----------GERGAPGNRGFPGQDGLAGP 457
Query: 338 EPSPGAGEPSK-AGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
+ +PG PS AGP GA G GR P G G G RP P K G G
Sbjct: 458 KGAPGERGPSGLAGPKGAN-GDPGRPGEPGLPGARGLTG-----RPGDAGPQGKVGPSGA 511
Query: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYAT-GKASGAG--GAGGQAYSPGQP--QGL 451
G P P + P GP A GKA G GA G PG+ G
Sbjct: 512 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 571
Query: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511
GP G G + + + PS G P PP P G Q + L G +G
Sbjct: 572 AGPPGPA-GPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 630
Query: 512 EP-YPG----PAAHSQGLPTASPSLSYSTGHSPAL--SGHGGGWGPSSLGG-GGEASPSH 563
E +PG P A P P + G A +G G GP L G GE +
Sbjct: 631 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 690
Query: 564 IIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK--GDG 621
I P G G GAPGK L + PPG AGA G KG+ G
Sbjct: 691 IAGPKGDRGDVGEK---GPEGAPGKDGGRGLTGP--IGPPGP----AGANGEKGEVGPPG 741
Query: 622 SELLAGPGGPPAERTEDEEFLIQHLLQAPS----PPRTSGADGLVGEDGAADASKGLGGS 677
AG G P ER E P+ PP G G GE G A KG G+
Sbjct: 742 PAGSAGARGAPGERGETGP-------PGPAGFAGPPGADGQPGAKGEQGEA-GQKGDAGA 793
Query: 678 GGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGE 737
G GP G P PQ T + +GA RG +
Sbjct: 794 PGPQGPSGAP------GPQG-------PTGVTGPKGA-------------------RGAQ 821
Query: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLE------AGGPDLP 791
P G AT GA + +P PP P S + P G + AG P L
Sbjct: 822 GPPG-ATGFP--GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878
Query: 792 LVLPPP-----PPQLLPSVLSHAPSPSPSASKVGVHLL-----------------EPATR 829
PP P PS P P A + G+ L EP +
Sbjct: 879 GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG-K 937
Query: 830 DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE--PAAPSPRLRPEESLDPPGAMQELLGAL 887
GAP PP P P L G E P A P R + + G E
Sbjct: 938 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGR-DGAAGVKGDRGETGAVG 996
Query: 888 EP-LPPAPGDTG-VGPPNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
P P PG G GP +G + AGA P G R I P D+
Sbjct: 997 APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR-----GIQGPQGPRGDKGE 1051
Query: 945 SFFPTMEEMFGG-GAADDYGKAGPPEDEGDPKAG--AGP--PPGPPAYDPYGPYCPGRAS 999
+ P + G G G GPP GD A AGP P GPP P GP A+
Sbjct: 1052 AGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG--PVGPSGKDGAN 1109
Query: 1000 GAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGL 1059
G PG P PP P G +SG + P PP P PP P P G+
Sbjct: 1110 GI----PG----PIGPPG--------PRG--RSG--ETGPAGPPGNPGPPGPPGPPGPGI 1149
Query: 1060 TSPIFCSTKPKK 1071
F P++
Sbjct: 1150 DMSAFAGLGPRE 1161
Score = 119 bits (299), Expect = 2e-26
Identities = 319/1253 (25%), Positives = 395/1253 (31%), Gaps = 318/1253 (25%)
Query: 204 GFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSP 263
GF+ AGG LG P P P PP P P E P
Sbjct: 117 GFDEKAGGAQLG------VMQGPMGPMGPRGPPGPAGAP------GPQGFQGNPGEPGEP 164
Query: 264 QLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSM 323
+ G P PP + P D +P A PP P A + + G
Sbjct: 165 GVSGPMGPRGPPGPPGK--PGDDG---EAGKPGKAGERGPPGPQGA-RGFPGTPGLPGVK 218
Query: 324 GHRA-----------------NLACSPLGGGEPSPGA-----GEPSKAGPSGATAGASGR 361
GHR + SP G P P GE + GP+GA AGA G
Sbjct: 219 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGA-AGARGN 277
Query: 362 ATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG 421
P AG G G GG PG+ G G A R P + + G
Sbjct: 278 DGQPGPAGPPGPVGPAGG-------PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330
Query: 422 GPAAAYATGK--------ASGAGGAGGQAYSPG--------QPQGLLGP-----QAYGQG 460
P A A+G A G+ GA G A +PG PQG GP Q G
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390
Query: 461 FGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQ--GEPYPGPA 518
G + + + P GP P P P G +G+ GV G P A
Sbjct: 391 IAGFKGE---QGPKGEPGPAGPQGAPGPAG-----EEGKRGARGEPGGVGPIGPPGERGA 442
Query: 519 AHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGG-------------------GEA 559
++G P L+ G +P G G GP G G+A
Sbjct: 443 PGNRGFP-GQDGLAGPKG-APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500
Query: 560 SPSHIIRPLQSPPATGRP-----------PGV-------GSPGAPGKYLSSVLASAPFL- 600
P + P +P GRP PGV G+ G PGK L AP L
Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLR 560
Query: 601 ------------APPGAGSYAAGAGGYKGKG-DGSELLAGPGGPPAERTEDEEFLIQHLL 647
PPG A G G G + L GP GPP E + + +
Sbjct: 561 GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620
Query: 648 QAPSPPRTSGADGLVGEDGAADA-----------SKGLGGSGGAGGPPGTPYELAKEDPQ 696
AP G G GE G+ A + G G GA GP G P + P
Sbjct: 621 GAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPP---GAQGPP 677
Query: 697 RYHLQSVIRTSASL-----------DEGATAALELGLGRLKEKKKGP--------ERGGE 737
R +A + ++G A GR GP E+G
Sbjct: 678 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737
Query: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPP-----PTAQSTQPTPHGLLLEAG------ 786
P G A S AGA+ ++ PP P P QP G EAG
Sbjct: 738 GPPGPAGS-----AGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792
Query: 787 --GPDLPLVLPPP--PPQLL-PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP 841
GP P P P P + P A P + G A R G P P P
Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGA-----AGRVGPPGSNGNPGP 847
Query: 842 PPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
P PP P + + G PPG E G P P PG+ G
Sbjct: 848 PGPPGPSGKDGPKGARG--------------DSGPPGRAGE-PGLQGPAGP-PGEK--GE 889
Query: 902 PNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
P +G P+GA P PQG R + + P Q ER FP + G + +
Sbjct: 890 PGDDG--PSGAEGPPGPQGLAGQRGI----VGLPG---QRGERG-FPGLP-----GPSGE 934
Query: 962 YGKAGPPEDEGD--PKAGAGPP-----------PGPPAYDPYGPYCPGRASGAG-----P 1003
GK G P GD P GPP G P D GP PGR AG
Sbjct: 935 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD--GP--PGRDGAAGVKGDRG 990
Query: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPI 1063
ET +G P P S A P G + G A P P PA A G+ P
Sbjct: 991 ETGAVGA-PGAPGPPGSPGPAGPTG--KQGDRGEAGAQGPMGPSGPAGAR----GIQGP- 1042
Query: 1064 FCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR--- 1120
Q P+ D+ +A P + L R
Sbjct: 1043 -------------------------QGPR----------GDKGEAGEPGERGLKGHRGFT 1067
Query: 1121 ----LPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRP-R 1175
LP + A P G P PGP GP + GPP PRGR
Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGP-PGPVGPSGKDGANGIPGPIGPPGPRGRSGE 1126
Query: 1176 IRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAG 1235
P P GP P G G A G R + PL+ + AG
Sbjct: 1127 TGPAGPPGNPGPPGPPGPP---------GPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1177
Query: 1236 EGLGTSSGDAISGTDHNSLDSSL--------TREKIEAKIKEVEEKQPEMKSG 1280
G DA SL++ + +R+ ++++ PE KSG
Sbjct: 1178 ---GLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSG 1227
Score = 117 bits (292), Expect = 1e-25
Identities = 330/1306 (25%), Positives = 407/1306 (31%), Gaps = 207/1306 (15%)
Query: 327 ANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQS 386
A L C +P P G+ + G G G GP+ G G G + +
Sbjct: 19 AVLRCQGQDVRQPGP-KGQKGEPGDIKDIVGPKG-PPGPQGPAGEQGPRGDRGDKGEKGA 76
Query: 387 PGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGP-AAAYATGKASGAGGAG-GQAYS 444
PG + G+ G G P PP P LGG AA A G AGGA G
Sbjct: 77 PGPR-GRDGEPGTPGNPGPPGPPGPPGPP---GLGGNFAAQMAGGFDEKAGGAQLGVMQG 132
Query: 445 PGQPQGLLGPQAYG-----QGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSP 499
P P G GP QGF G + S GP PP P PG
Sbjct: 133 PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG--------- 183
Query: 500 DQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHS--PALSGHGGGWGPSSL---- 553
D + G GE P ++G P +P L GH P L G G G +
Sbjct: 184 DDGEAGKPGKAGERGPPGPQGARGFP-GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242
Query: 554 GGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG 613
G GE + P P GR G+ GA G A P P G GA
Sbjct: 243 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 302
Query: 614 GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKG 673
G KG+ G GP G R E P P +GA G G DG A KG
Sbjct: 303 GAKGEA-GPTGARGPEGAQGPRGEPG---------TPGSPGPAGASGNPGTDGIPGA-KG 351
Query: 674 LGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP- 732
G+ G G PG P PQ T +G T E G+ K ++ GP
Sbjct: 352 SAGAPGIAGAPGFPGPRGPPGPQG-------ATGPLGPKGQTG--EPGIAGFKGEQ-GPK 401
Query: 733 -ERGGETPEGLATSVVHYGA-GAKELGAFLQKSPPPPPPTAQSTQ--PTPHGLLLEAGGP 788
E G P+G G GA+ + PP A + P GL G P
Sbjct: 402 GEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAP 461
Query: 789 D----LPLVLPP--------PPPQLLPSV--LSHAPSPSPSASKVGVHLLEPATRDGAPQ 834
L P P LP L+ P + KVG GAP
Sbjct: 462 GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP--------SGAPG 513
Query: 835 PPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAP 894
P PP P + G + A P E+ L PGA L LP
Sbjct: 514 EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL--PGAP-----GLRGLPGKD 566
Query: 895 GDTGV-GPPNSEGK----------DPAGAYRSPSPQGTKAPRFVP----LTSICFPDSLL 939
G+TG GPP G P+G P P G P + L+
Sbjct: 567 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626
Query: 940 QDEERSFFPTMEEMFGG-GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYG----PYC 994
FP G G G G P +G PK +GP P A P G P
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG-PKGASGPAGPPGAQGPPGLQGMPGE 685
Query: 995 PGRASGAGPETPGLGLDPNKPPELPSTVNAE----PLGLIQSGPHQAAPPPPPPPPPPPA 1050
G A AGP+ + P P P+G GP A PP PA
Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG--PPGPAGANGEKGEVGPPGPA 743
Query: 1051 PASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADV 1110
++ +G P + +T PP + A+ + EA + K D
Sbjct: 744 GSAGARGA----------PGERGETGPPGPAGFAGPPGADGQP-GAKGEQGEAGQ-KGDA 791
Query: 1111 PADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP--GPDGPRRRGRKPTKAKRDGPP 1168
A P P P G P G GP P A R GPP
Sbjct: 792 GAPGPQGPSGAP------------GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839
Query: 1169 RPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIK 1228
G P P GP+ DG K RG GR E
Sbjct: 840 GSNGNPG-----PPGPPGPSGK----DGPKGARGDSGPPGRAGEPG-------------- 876
Query: 1229 LSVPKAGEG-LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLD 1287
L P G G D SG + L ++ I + ++ E GF
Sbjct: 877 LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQRGER--GFPGLPGP 931
Query: 1288 FLKSGKRHPPLYQAGLTPPLSPPKSV-PPSVPARGLQPQPPATPAVPHPPP-SGAFGLGG 1345
+ GK+ P G + PP V PP + +P +P PP GA G+ G
Sbjct: 932 SGEPGKQGAP----GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987
Query: 1346 ALEAAESEGLGL-GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA 1404
+ E+ +G G P P S K D E+ +
Sbjct: 988 --DRGETGAVGAPGAPGP----------------PGSPGPAGPTGKQGDRGEAGAQGPMG 1029
Query: 1405 LDDPPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPP 1462
P AG + P GP A PG L G G P PP + P
Sbjct: 1030 PSGP--AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087
Query: 1463 PAPTPQPQPPPPPPPPQP----ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
P+ PP P P +P P P S P PP P P PP PP P
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147
Query: 1519 AAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEE 1564
A P P+ PL + + A + D E
Sbjct: 1148 GIDMSAFAGLGPREKGPD--------PLQYMRADQAAGGLRQHDAE 1185
Score = 64.7 bits (156), Expect = 9e-10
Identities = 270/1152 (23%), Positives = 346/1152 (30%), Gaps = 251/1152 (21%)
Query: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELL 884
EP T G P PP PP PP PP A + G + A +L G MQ +
Sbjct: 85 EPGT-PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL---------GVMQGPM 134
Query: 885 GALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
G + P P PG G P +P G P G PR P P D+
Sbjct: 135 GPMGPRGP-PGPAGAPGPQGFQGNP-GEPGEPGVSGPMGPRGPP-----GPPGKPGDDGE 187
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
+ P G A + G GP G P G PG + Y P G AG
Sbjct: 188 AGKP--------GKAGERGPPGPQGARGFP--GTPGLPGVKGHRGY-PGLDGAKGEAG-- 234
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLI----QSGPHQAAPPPPPPPPPPPAPASEPKGGLT 1060
PG+ + P E S P GL ++GP AA P PA P G
Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294
Query: 1061 SPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR 1120
P F K P AQ E + PA NP
Sbjct: 295 GPGFPGAPGAK-----------GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT 343
Query: 1121 --LPDLVSSCRSRPALS-------PLGDIDFCPPNP----GPDGPRRRGRKPTKAKRDGP 1167
+P S + P ++ P G PP P GP GP+ + +P A G
Sbjct: 344 DGIPGAKGSAGA-PGIAGAPGFPGPRG-----PPGPQGATGPLGPKGQTGEPGIAGFKGE 397
Query: 1168 PRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLK---P 1224
P+G P AGP A P K RG G G R P P
Sbjct: 398 QGPKGEPG--------PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 449
Query: 1225 LKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREK----IEAKIKEVEEKQPEMKSG 1280
+ L+ PK G SG ++G + D E + P+ K G
Sbjct: 450 GQDGLAGPKGAPGERGPSG--LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 507
Query: 1281 FMASFLDFLKSGKRHPPLYQ----------------AGLTPPLSPPKSVPPSVPARGLQP 1324
+ + G+ PP Q A P + K +P + RGL
Sbjct: 508 PSGAPGE---DGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 564
Query: 1325 QPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSS-- 1382
+ T A P P+G G G A G G P P E K + +P +
Sbjct: 565 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ-GLPGPPGPPGEGGKPGDQGVPGEAGAP 623
Query: 1383 -------DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPP 1435
+ + + + P GPK S P GPP A GPP
Sbjct: 624 GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-----GPPG 678
Query: 1436 LPGLPSANSNGTPEPPL-----LEEKPP--------------PTPPPAPT----PQPQPP 1472
L G+P P + EK P P PP P + +
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738
Query: 1473 PPPP-----------------PPQPALPSPPPLV--------------------APTPSS 1495
PP P PP PA + PP AP P
Sbjct: 739 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 798
Query: 1496 PPPPPLPPPP-----PPAMPSPPPPPP----PAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
P P P P P PP P AA PP P P P P +
Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG 858
Query: 1547 HLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRV 1606
+ ++ AGE G +G E +D PS G E PP
Sbjct: 859 PKGARGDSGP-----PGRAGEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPP---- 902
Query: 1607 QKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKP 1666
P+ GQR G G R +R + +
Sbjct: 903 --------GPQGLAGQR---------GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 945
Query: 1667 WHRPPVPVRR---SGQAKNPVSAG--GSSAPPPK-----------------APAPPPKPE 1704
PP PV +G A P G G+ PP + AP P P
Sbjct: 946 DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPG 1005
Query: 1705 TPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE-----KEKEKEKVTRGERPLRGERA 1759
+P E P P P+ R ++ + + E GER L+G R
Sbjct: 1006 SPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRG 1065
Query: 1760 TSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGG-GPPGS 1818
+G Q P +G S A P+ + P P + G N G GPPG
Sbjct: 1066 FTGLQGLPGPPGPSGDQGAS--GPAGPSGPRGPPGPVGPS---GKDGANGIPGPIGPPGP 1120
Query: 1819 SSDS-ESSPGAP 1829
S E+ P P
Sbjct: 1121 RGRSGETGPAGP 1132
Score = 62.8 bits (151), Expect = 3e-09
Identities = 131/506 (25%), Positives = 162/506 (32%), Gaps = 80/506 (15%)
Query: 584 GAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLI 643
GAP + L A L G G G KG+ + + GP GPP + E
Sbjct: 5 GAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGE--- 61
Query: 644 QHLLQAPSPPR-TSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQS 702
Q P R G G G G D G G+ G GPPG P P
Sbjct: 62 ----QGPRGDRGDKGEKGAPGPRG-RDGEPGTPGNPGPPGPPGPP------GPPGLGGNF 110
Query: 703 VIRTSASLDEGATAALELGLGRLKEKKKGPE-----RGGETPEGLATSVVHYGAGAKELG 757
+ + DE A A +LG+ + GP G P+G + G G
Sbjct: 111 AAQMAGGFDEKAGGA-QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS-G 168
Query: 758 AFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQ---------LLPSVLSH 808
+ PP PP +P G EAG P PP PQ LP V H
Sbjct: 169 PMGPRGPPGPP-----GKPGDDG---EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 220
Query: 809 APSPSPSASKVGVHLLEPATRDGAP-QPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPR 867
P +K G+P + P P P +P G A +
Sbjct: 221 RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP-------GERGRTGPAGAAG 273
Query: 868 LRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927
R + P G P+ PA G G P ++G+ AG + P+G + PR
Sbjct: 274 ARGNDGQPGPA------GPPGPVGPAGGPGFPGAPGAKGE--AGPTGARGPEGAQGPRGE 325
Query: 928 PLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDY----GKAGPPEDEGDPK-AGAGPPP 982
P T P S P G D G AG P G P G PP
Sbjct: 326 PGT----PGS----------PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 371
Query: 983 GPP-AYDPYGPYC----PGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQA 1037
GP A P GP PG A G + P P P P E + P
Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV 431
Query: 1038 APPPPPPPPPPPAPASEP-KGGLTSP 1062
P PP P P + GL P
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGP 457
Score = 40.8 bits (94), Expect = 0.014
Identities = 135/532 (25%), Positives = 162/532 (30%), Gaps = 110/532 (20%)
Query: 1319 ARGLQPQP-PATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETL 1377
ARG QP PA P P P G G GA A+ E G P E +
Sbjct: 274 ARGNDGQPGPAGPPGPVGPAGGP-GFPGA-PGAKGEAGPTGARGP------EGAQGPRGE 325
Query: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP-GPPPL 1436
P + A + I A + P +AG P GPP A P GP
Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385
Query: 1437 PGLPS-ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495
G P A G E+ P P PA PQ P P + P V P
Sbjct: 386 TGEPGIAGFKG-------EQGPKGEPGPAG-PQGAPGPAGEEGKRGARGEPGGVGPIG-- 435
Query: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS--------PEDPELPDTRPLH 1547
PP P P P AP P A P P +P LP R
Sbjct: 436 -PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG-- 492
Query: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPI---W 1604
L + A G+ G SG G + GR PP
Sbjct: 493 LTGRPGDAGPQGKV----GPSGAPG----------------------EDGRPGPPGPQGA 526
Query: 1605 RVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCAR 1664
R Q ++ P+ +G+ G G L + KD A
Sbjct: 527 RGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG-------------LRGLPGKDGETGAAG 573
Query: 1665 KPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMP 1724
P P P G+ P +G P P P PP + KP +Q
Sbjct: 574 PPG--PAGPAGERGEQGAPGPSGFQGLPGP--PGPPGE--------GGKPGDQGV----- 616
Query: 1725 EPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKA 1784
P P L+ P RGER GER + G Q G P T PK
Sbjct: 617 -PGEAGAPGLVGP-----------RGERGFPGERGSPGAQGLQGPRGLPGTPGTDG-PKG 663
Query: 1785 RPTKVKAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSD-SESSP-GAPSED 1832
A PP + L+ G A G GP G D E P GAP +D
Sbjct: 664 --ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713
Score = 33.1 bits (74), Expect = 2.8
Identities = 40/155 (25%), Positives = 45/155 (29%), Gaps = 21/155 (13%)
Query: 1431 PGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPL-- 1488
P PP P P+ + EK P P P P PP P P PP L
Sbjct: 49 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGG 108
Query: 1489 ---------VAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP--LAAPPEEPAAPSPED 1537
+ P P P PP P A P P EP P
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSG 168
Query: 1538 PELPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
P P P K + D EAG+ G G
Sbjct: 169 PMGPRGPPGPPGKPGD--------DGEAGKPGKAG 195
Score = 31.6 bits (70), Expect = 8.3
Identities = 42/180 (23%), Positives = 59/180 (32%), Gaps = 38/180 (21%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP-----------KPETPEKTTSEKPPEQT 1718
PP P +G P G + P P A PP + E +K + P Q
Sbjct: 739 PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG 798
Query: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPAT 1778
P A P P+ P+ G + RG + G P + G P +
Sbjct: 799 PSGA----PGPQGPT-------------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841
Query: 1779 SRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPG 1838
+ P PP K K A G++ GPPG + + A E+ PG
Sbjct: 842 NGNPG------PPGPPGPSGKDGPKGARGDS----GPPGRAGEPGLQGPAGPPGEKGEPG 891
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 130 bits (326), Expect = 2e-29
Identities = 267/1039 (25%), Positives = 337/1039 (32%), Gaps = 181/1039 (17%)
Query: 80 GSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGS 139
G AGP + A+ GP+ P L +P + A PG +PGS
Sbjct: 321 GEAGPTGPM----GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGS 376
Query: 140 STFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTV 199
S FP + + P G+R P Q PP P +P +
Sbjct: 377 SGFPGNPGMKGEAGPT--GARG---PEGPQGQRGETGPPG-------------PVGSPGL 418
Query: 200 PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAE 259
P ++G + G GP G PP GPP P P S+ +
Sbjct: 419 PGAIGTDGTPGAK--GPTGSPGTSGPPGSAGPPGSPGPQ----------GSTGPQGIRGQ 466
Query: 260 QSSPQLYNFSGAA-----PGP--------PPPERAL--PRQDTVIKHYQRPASAQPPPPP 304
P + F G A PGP PP E PR D P + PP P
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGD--------PGTVGPPGPV 518
Query: 305 PPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEP-SKAGPSGATAGASGRAT 363
G + G+R L G + + G P +GP G+ G GR
Sbjct: 519 -------------GERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQ-GDPGRPG 564
Query: 364 GPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTAT---PKCQSL 420
P G G G G +Q P K G G A G RP PP S P L
Sbjct: 565 EPGLPGARGLTGNPG-----VQGPEGKLGPLG---APGEDGRPGPPGSIGIRGQPGSMGL 616
Query: 421 GGPAAAYAT-GKASGAGGAG--GQAYSPGQ-----PQGLLGPQAYGQGFGGGQAQDLSKA 472
GP + GK AG AG GQ +PG+ P G +GP G G + +
Sbjct: 617 PGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP----GLAGERGEQGPPG 672
Query: 473 PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLS 532
P+ G P PP P G Q D G +GE G+
Sbjct: 673 PTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKG 732
Query: 533 YSTGH-------SPALSGHGGGWGPSSLGG-GGEASPSHIIRPLQSPPATGRPPGVGSPG 584
+ GH SP SG G GP L G GE + +P G G+G G
Sbjct: 733 MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG------TPGPKGDRGGIGEKG 786
Query: 585 APGKYLSSVLASAPF-LAPPGAGSYAAGAGGYKGKGDGSELLAGPG--GPPAERTEDEEF 641
A G + P L PPG AG G KG+ L+ PG G P R E+
Sbjct: 787 AEGTAGNDGARGLPGPLGPPGP----AGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842
Query: 642 LIQHLLQAPSPPRTSGADGLVGE-----DGAADASKGLGGSGGAGGPPGTPYELAKEDPQ 696
P G G GE D + +GL GS G GP G P Q
Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP--ERGGETPEGLATSVVHYGAGAK 754
+ SA A G GP E G E P GL +G
Sbjct: 903 GPPGATGFPGSAGRVGPPGPAGAPG-------PAGPLGEPGKEGPPGLRGDPGSHGRVGD 955
Query: 755 ELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSP 814
A P + QP P G AG ++ P Q + P P+
Sbjct: 956 RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPG-QRGERGMPGLPGPAG 1014
Query: 815 SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL---EAHLRSHGLEPAAPSPRLRPE 871
+ KVG P G PP P PP P+ E + G + R +
Sbjct: 1015 TPGKVG-----PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGD 1069
Query: 872 ESLDPPGAMQELLGALEPLPP--APGDTGV-GPPNSEGK----DPAGAYRSPSPQGTKAP 924
P + GA P APGD G G P S G AG P PQG +
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGD 1129
Query: 925 RFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
+ + + G G GPP G+ G+ PGP
Sbjct: 1130 K----------------GDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ--GSAGIPGP 1171
Query: 985 PAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPP 1044
+ P GP PG +G E L P PP + +V +A P PP
Sbjct: 1172 --FGPRGP--PGPVGPSGKEGNPGPLGPIGPPGVRGSVG------------EAGPEGPPG 1215
Query: 1045 PPPPPAPASEPKGGLTSPI 1063
P PP P P G LT+ +
Sbjct: 1216 EPGPPGPPG-PPGHLTAAL 1233
Score = 120 bits (300), Expect = 2e-26
Identities = 259/956 (27%), Positives = 307/956 (32%), Gaps = 215/956 (22%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GP G+ P +PG P PP P H P L SA A ++ S L + G
Sbjct: 153 GPRGPQGIDGEPGVPGQPGAPGPPGHPSH-PGPDGLSRPFSAQMAGLDEKS-GLGSQVGL 210
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
PG P PR ++ Q A PP P G MG
Sbjct: 211 MPGSVGP--VGPRGPQGLQGQQGGAGPTGPPGEP------------GDPGPMG------- 249
Query: 332 SPLGGGEPSPGAGEPSKAGPSG--ATAGASGRATGPEAAGGGGAGG--GGGGYRPIIQSP 387
P+G P G+P + G G G G A P A G GA G G G+R
Sbjct: 250 -PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR---GHK 305
Query: 388 GYKTGKGGYGA-AAGGATRPPPPRSTATP-KCQSLGGPAAAYATGKASGAGGAGGQAYSP 445
G + KG GA + G P P P + + G A G GA G P
Sbjct: 306 GLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKP 365
Query: 446 GQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQP-----PSGPP----PPGLATCQS 496
G P G LG GF G P+ + GP P +GPP PGL +
Sbjct: 366 G-PMGPLGIPG-SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLP--GA 421
Query: 497 YSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTG--------HSPALSGHGGGW 548
D G G G P S G P SP STG P + G G
Sbjct: 422 IGTDGTPG-AKGPTGSPGTSGPPGSAG-PPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEA 479
Query: 549 GPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSY 608
GP GE P I P+ P G+ G PG G PPG
Sbjct: 480 GPK-----GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG--------------PPGPVG- 519
Query: 609 AAGAGGYKGKGDGSELLAGPGGPPAER---TEDEEFLIQHLLQAPSPPRTSGADGLVGED 665
GA G +G GS+ L GP G ER Q P P GA GL G
Sbjct: 520 ERGAPGNRG-FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNP 578
Query: 666 GAADASKGLG--GSGGAGGPPGTPYELA-KEDPQRYHLQSVIRTSASLDEGATAALELGL 722
G LG G+ G G PG P + + P L +S D G E G
Sbjct: 579 GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPG--PKGSSGDPGKPG--EAGN 634
Query: 723 GRLKEKKKGPERGGET-------PEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQ 775
+ ++ P + GE P GLA G Q P PP P + +
Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP---TGFQGLPGPPGPPGEGGK 691
Query: 776 PTPHGLLLEAG-----------------------------------GPDLPLVLP----- 795
P G+ + G GPD P P
Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751
Query: 796 -----PPPPQLLPSVLSHAPSPSPSASKVGV---HLLEPATRDGAPQPPPPPPPPPPPMP 847
PP Q +P A +P P + G+ A DGA P P PP P P
Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811
Query: 848 LQLEAHLRSHGLEPAAPSPR--LRPEESLDPPGAMQE-----LLGALEPLPP--APGDTG 898
E P PR + P S PG+ E +G P P PG G
Sbjct: 812 TG----------EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861
Query: 899 -VGPPNSEG----KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEM 953
G P +G P G SP P G P VP
Sbjct: 862 EPGEPGQKGDAGSPGPQGLAGSPGPHG---PNGVP------------------------- 893
Query: 954 FGGGAADDYGKAGPPEDEGDP-KAGAGPPPGPP-AYDPYGPYCPGRASGAGPETPGLGLD 1011
G G GPP G P AG PPGP A P GP G GP PGL D
Sbjct: 894 ---GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL--GEPGKEGP--PGLRGD 946
Query: 1012 PNKPPELPSTVNAEPLGLIQSGPHQAAPP-----PPPPPPPPPAPASEPKGGLTSP 1062
P + A P G GP P P P PP PA + +G + P
Sbjct: 947 PGSHGRVGDRGPAGPPG----GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP 998
Score = 110 bits (274), Expect = 2e-23
Identities = 277/1053 (26%), Positives = 340/1053 (32%), Gaps = 222/1053 (21%)
Query: 311 QHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGG 370
Q L C G + GGG + G G + G G +G P AG
Sbjct: 77 QDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP 136
Query: 371 GGAGGGGGGYRPIIQSPGYKTGKG--GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA 428
G+ G G P + PG + +G G G P PP + P L P +A
Sbjct: 137 PGSQGPRGERGPKGR-PGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQM 195
Query: 429 TG--KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGP 486
G + SG G G P G GPQ QG GG GP PP P
Sbjct: 196 AGLDEKSGLGSQVGLMPGSVGPVGPRGPQGL-QGQQGG------------AGPTGPPGEP 242
Query: 487 PPPG-LATCQSYSPDQLQGQLYGVQGEP----YPGPAAHS-----QGLPTAS--PSLSYS 534
PG + S P+ G+ G GEP PG + +G P A P L
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKP-GEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301
Query: 535 TGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVL 594
GH G P S G G P + PL G +G GAPG+ + +
Sbjct: 302 RGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGM 361
Query: 595 ASAPF----LAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAP 650
P L PG+ + G G KG+ G GP GP +R E P
Sbjct: 362 PGKPGPMGPLGIPGSSGF-PGNPGMKGEA-GPTGARGPEGPQGQRGE---------TGPP 410
Query: 651 SPPRTSGADGLVGEDGAADA-----SKGLGGSGGAGGPPGTPYELAKEDPQRYHLQ---- 701
P + G G +G DG A S G G G+ GPPG+P PQ Q
Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDP 470
Query: 702 ---SVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGA 758
+ E ++ +G E+ K RG G V GA
Sbjct: 471 GVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNR--G 528
Query: 759 FLQKSPPPPPPTAQSTQ-----------------------PTPHGLLLEAG--GPD---L 790
F P P AQ + P GL G GP+
Sbjct: 529 FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588
Query: 791 PLVLP-----PPPPQLL-------------PSVLSHAPSPSPSASKVGVHLLEPAT-RDG 831
PL P P PP + P S P A GV A +DG
Sbjct: 589 PLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648
Query: 832 APQPPPPPPPP---------PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP-----P 877
P P PP PP P + GL P P P P E P P
Sbjct: 649 EVGPSGPVGPPGLAGERGEQGPPGPTGFQ------GL-PGPPGP---PGEGGKPGDQGVP 698
Query: 878 GAMQELLGALEPLPPA-----PGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928
G GA+ PL P PG+ G G P +G AG + P+G+ P P
Sbjct: 699 GDP----GAVGPLGPRGERGNPGERGEPGITGLPGEKGM--AGGHGPDGPKGSPGPSGTP 752
Query: 929 LTSICFPDSLLQDEERSFFPTM----------EEMFGGGAADD-----------YGKAGP 967
P ER T E+ G A +D G AGP
Sbjct: 753 -GDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811
Query: 968 PEDEGDP-KAGAGPPPG----PPAYDPYGPYCPGRASGAGPE----TPGLGLDPNKPPEL 1018
++G+P G PPG P + GP G AGP+ PG+ +P +P +
Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGP--TGAVGFAGPQGPDGQPGVKGEPGEPGQK 869
Query: 1019 PSTVNAEPLGLIQS-GPHQAAPPP--------PPPP-------------PPPPAPASEPK 1056
+ P GL S GPH P PP PP PA A P
Sbjct: 870 GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA 929
Query: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
G L P P L H P P DK D D +
Sbjct: 930 GPLGEP--GKEGPPGLRGDPGSHGRVGDRGPAGPP----------GGPGDKGDPGEDGQP 977
Query: 1117 NPRRLPDLVSSCRSRPALSPLGDID--FCPPNPGPDG-PRRRGRKPTKAKRD-GPPRPRG 1172
P P + R + G P PGP G P + G PT A D GPP P G
Sbjct: 978 GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG--PTGATGDKGPPGPVG 1035
Query: 1173 RPRIR-PLEVPTTAGPA-SASTP-TDGAKKPRG 1202
P P+ P GPA + TP DGA RG
Sbjct: 1036 PPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068
Score = 66.2 bits (160), Expect = 3e-10
Identities = 290/1217 (23%), Positives = 363/1217 (29%), Gaps = 259/1217 (21%)
Query: 406 PPPPRSTATPKC-QSLGGPAAAYATGK------------ASGAGGAGGQAYSPGQ--PQG 450
P P P C Q+ GG + G+ +G G G A PG P+G
Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144
Query: 451 LLGPQAYGQGFGGGQAQDLSKAPSYSG--GPPQPPSGPPPPGLATCQSYSPDQLQGQLYG 508
GP+ G P G GPP PS P P GL+ Q+ G
Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSR-------PFSAQMAG 197
Query: 509 VQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPL 568
+ + G GL S G L G GG GP+ G GE + P+
Sbjct: 198 LDEKSGLGSQV---GLMPGSVGPVGPRGPQ-GLQGQQGGAGPT--GPPGEPGDPGPMGPI 251
Query: 569 QSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAG--------GYKG--- 617
S G P G G PG+ + F PGA + G G+KG
Sbjct: 252 GSRGPEGPPGKPGEDGEPGR--NGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEG 309
Query: 618 -KGD----GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASK 672
KG+ GS+ AGP GP P PR G+ GE G +
Sbjct: 310 PKGEVGAPGSKGEAGPTGPMGA-------------MGPLGPR-----GMPGERGRL-GPQ 350
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP 732
G G GA G PG P + L ++ G E
Sbjct: 351 GAPGQRGAHGMPGKPGPMGP-----------------LGIPGSSGFPGNPGMKGEAGPTG 393
Query: 733 ERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPP-----PTAQSTQPTPHGLLLEAGG 787
RG E P+G + PP P P A T TP A G
Sbjct: 394 ARGPEGPQGQRG----------------ETGPPGPVGSPGLPGAIGTDGTPG-----AKG 432
Query: 788 PDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP------P 841
P PP P +P P S G+ G P P P P
Sbjct: 433 PTGSPGTSGPPGSAGPP---GSPGPQGSTGPQGIR--------GQPGDPGVPGFKGEAGP 481
Query: 842 PPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
P P ++ + G E PR P ++ PPG + E APG+ G
Sbjct: 482 KGEPGPHGIQGPIGPPG-EEGKRGPRGDPG-TVGPPGPVGER--------GAPGNRGF-- 529
Query: 902 PNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFG----G 956
P S+G P GA P G+ P+ D R P + G
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPK-----------GSQGDPGRPGEPGLPGARGLTGNP 578
Query: 957 GAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP 1016
G GK GP G P G PGPP PG GP+ G DP KP
Sbjct: 579 GVQGPEGKLGPL---GAP--GEDGRPGPPGSIGIRGQ-PGSMGLPGPK--GSSGDPGKPG 630
Query: 1017 ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
E NA G + P P PP + G P T
Sbjct: 631 EAG---NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP------------TG 675
Query: 1077 SFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR-LNPRRLPDLVSSCRSRPALS 1135
L PP + K D+ P + L PR R P ++
Sbjct: 676 FQGLPGPPGPPGEGGKP---------GDQGVPGDPGAVGPLGPRGERGNPGE-RGEPGIT 725
Query: 1136 PLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTD 1195
L GPDGP+ GPP +G P R + A TP
Sbjct: 726 GLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGI----------AGTPG- 774
Query: 1196 GAKKPRGRGRGRGRKAEE--AGGTRLEPLK-PLKIKLSVPKAGEGLGTSSGDAISGTDHN 1252
P+G G G K E AG L PL GE +
Sbjct: 775 ----PKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830
Query: 1253 SLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSP--P 1310
S + + P+ + G + + G P Q GL P P
Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ-GLAGSPGPHGP 889
Query: 1311 KSVPPSVPARGLQPQPPATP------AVPHPPPSGAFGLGGALEAAESEGL-GL-GCPSP 1362
VP RG Q P AT V P P+GA G G L EG GL G P
Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGS 949
Query: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGP 1422
R+ + R P D+ D + D PP GP T+ G
Sbjct: 950 HGRVGD---RGPAGPPGGPGDKGDPGEDGQP----------GPDGPP--GPAGTTGQRGI 994
Query: 1423 PLAPAA-------AVPGPPPLPG-LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474
P +PGP PG + + G PP P PP + P +P P
Sbjct: 995 VGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP-----GPVGPPGSNGPVGEPGPE 1049
Query: 1475 PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP-----------PPPAAAPL 1523
P P V P P P P P P P + P+
Sbjct: 1050 GPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI 1109
Query: 1524 AAPPE--EPAAPSPEDP 1538
P + P P+ P
Sbjct: 1110 GPPGRAGKRGLPGPQGP 1126
Score = 51.2 bits (121), Expect = 1e-05
Identities = 106/438 (24%), Positives = 137/438 (31%), Gaps = 58/438 (13%)
Query: 99 GPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFG 158
GPQ + + P + +PGP L S G + P Q P G
Sbjct: 849 GPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPP--G 906
Query: 159 SRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLK-PSQAPTVPSSLGFERLAGGGVLGPA 217
+ FP S PP A G P + P P S G R+ G GP
Sbjct: 907 ATGFP--GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG--RVGDRGPAGPP 962
Query: 218 GLGPAQTPPYRPGPPDP--PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275
G + P G P P PP P Q ++ E+ P L +G PG
Sbjct: 963 GGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG---ERGMPGLPGPAGT-PGK 1018
Query: 276 PPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG--GSYPSMGHRANLACSP 333
P A + P S P P P + + G G+ G R + +
Sbjct: 1019 VGPTGATGDKGPP-GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAG 1077
Query: 334 LGGGEPSPGA-------------GEPSKAGPSGATAGASGRAT-GPEAAGGGGAGGGGGG 379
L G + +PG G+P GP G A R GP+ G G G
Sbjct: 1078 LPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRG 1137
Query: 380 YRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAG 439
R G+ G+ G P PP + GP + G G
Sbjct: 1138 DR----------GQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP---FGPRGPPGPVGPS 1184
Query: 440 GQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSP 499
G+ +PG P G +GP G P G P PP P PPG T
Sbjct: 1185 GKEGNPG-PLGPIGPPGVRGSVG-------EAGPEGPPGEPGPPGPPGPPGHLTA----- 1231
Query: 500 DQLQGQLYGVQGEPYPGP 517
G + G E P P
Sbjct: 1232 --ALGDIMGHYDESMPDP 1247
Score = 37.7 bits (86), Expect = 0.12
Identities = 111/458 (24%), Positives = 136/458 (29%), Gaps = 71/458 (15%)
Query: 1144 PPNPGPDGP---RRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTP----TDG 1196
P +PGP GP R P K DG P G P EV P + P G
Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG----EVGFAGSPGARGFPGAPGLPG 297
Query: 1197 AKKPRGRGRGRGRKAE--------EAGGT----RLEPLKPLKIKLSVPKAGEGLGTSSGD 1244
K RG G K E EAG T + PL P +P LG
Sbjct: 298 LKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR----GMPGERGRLGPQGAP 353
Query: 1245 AISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHP--PLYQAG 1302
G H + P MK + +G R P P Q G
Sbjct: 354 GQRGA-HGMPGKPGPMGPLGIPGSSGFPGNPGMKG-------EAGPTGARGPEGPQGQRG 405
Query: 1303 LTPPLSPPKSVPPSVP-ARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPS 1361
T P P S P +P A G P A P SG G G G P
Sbjct: 406 ETGPPGPVGS--PGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP----------GSPG 453
Query: 1362 PCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDG 1421
P + R P + ++ K I I + GP+ G
Sbjct: 454 PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG 513
Query: 1422 PPLAPAA--AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479
PP P PG PG S+G P P + + P P + P P +
Sbjct: 514 PP-GPVGERGAPGNRGFPG-----SDGLPGPKGAQGERGPVGSSGP--KGSQGDPGRPGE 565
Query: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
P LP L P L P P P PP + + P P P+
Sbjct: 566 PGLPGARGLTGNPGVQGPEGKLGPLGAPG--EDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623
Query: 1540 LPDTRPLHLAKKQETAAVCGE-----TDEEAGESGGEG 1572
+P + A V G+ D E G SG G
Sbjct: 624 GDPGKP----GEAGNAGVPGQRGAPGKDGEVGPSGPVG 657
Score = 33.1 bits (74), Expect = 2.8
Identities = 45/187 (24%), Positives = 65/187 (34%), Gaps = 23/187 (12%)
Query: 1678 GQAKNPVSAGGSSAPPPK-APAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR 1736
G A P S G P P AP + P PP + + +P P P
Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGP------- 1126
Query: 1737 PVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPK 1796
+ + + RG+R +G R +G Q P G+ ++ +P P + P P
Sbjct: 1127 ---RGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIP--GPFGPRGPPGPV 1181
Query: 1797 KRKKWLKEAGGNATAGGGPPG-----SSSDSESSPGAPS-EDERAVPGRLLKTRAMREMY 1850
KE GPPG + E PG P PG L T A+ ++
Sbjct: 1182 GPSG--KEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHL--TAALGDIM 1237
Query: 1851 RSYVEML 1857
Y E +
Sbjct: 1238 GHYDESM 1244
Score = 32.3 bits (72), Expect = 4.9
Identities = 43/171 (25%), Positives = 53/171 (30%), Gaps = 28/171 (16%)
Query: 1402 ISALDDPPLAGPKDTSTPDGPP-LAPAAAVPGPPPLPGLPSANSN--------------- 1445
+ A D G + P GPP A +PGP G + +
Sbjct: 1091 VGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGL 1150
Query: 1446 -GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP------PQPALPSPPPLVAPTPSSPPP 1498
G P PP + P P PP P P P P P PP V + P
Sbjct: 1151 QGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP 1210
Query: 1499 PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP-----EDPELPDTR 1544
P P P P PP AA + + P P ED PD +
Sbjct: 1211 EGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDK 1261
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 127 bits (319), Expect = 1e-28
Identities = 348/1399 (24%), Positives = 420/1399 (30%), Gaps = 363/1399 (25%)
Query: 192 KPSQAPTVPSSLGFERLAGGGVLGPAG-LGPAQTP--------PYRPGPPDPPPPPRHLP 242
+P APT P + G G GP G GP P P +PG P P PP
Sbjct: 90 QPPTAPTRPPN-------GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPP---- 138
Query: 243 TQFNLLASSSAAAAAAEQSSPQLYNF---SGAAPGPPPPERALPRQDTVIKHYQRPASAQ 299
+ + SPQ ++ SG A G + Y PA
Sbjct: 139 ------GICESCPTGPQNYSPQYDSYDVKSGVAVGG-------------LAGYPGPAG-- 177
Query: 300 PPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--G 357
PP PP P H GS S G++ G P GEP +AGPSG G
Sbjct: 178 PPGPPGPPGTSGH----PGSPGSPGYQ----------GPP----GEPGQAGPSGPPGPPG 219
Query: 358 ASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKG-----GYGAAAGGATRPPPPRST 412
A G +GP G G G R + PG K G G G R T
Sbjct: 220 AIG-PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278
Query: 413 ATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKA 472
P + G G GA G+ PG P G G + D ++
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP-----------GAAGARGNDGARG 327
Query: 473 PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLS 532
GPP PP PG SP G +GE P + S G P
Sbjct: 328 SDGQPGPPGPPGTAGFPG-------SP--------GAKGEVGPAGSPGSNGAP------- 365
Query: 533 YSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV-GSPGAPGKYLS 591
P GH G GP PPG+ GSPG G+
Sbjct: 366 -GQRGEPGPQGHAGAQGPPG------------------------PPGINGSPGGKGEMGP 400
Query: 592 SVLASAPFL----APPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLL 647
+ + AP L PPG A GA G +G G G G G P R E E I
Sbjct: 401 AGIPGAPGLMGARGPPGPAG-ANGAPGLRG-GAGEPGKNGAKGEPGPRGERGEAGI---- 454
Query: 648 QAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTS 707
P P G DG G G A+ GL G+ G G PG R
Sbjct: 455 --PGVPGAKGEDGKDGSPGEPGAN-GLPGAAGERGAPG------------------FRGP 493
Query: 708 ASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP 767
A + G EK ERG P G + G G ++ P P
Sbjct: 494 AGPN-----------GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP 542
Query: 768 PPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPA 827
+P P G E+G P P P P+ P V+ P P + G +
Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPP---GPSGPRGQPGVMGF-PGPKGNDGAPGKN----- 593
Query: 828 TRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGAL 887
G P P P PP G P P+ + PPG L
Sbjct: 594 GERGGPGGPGPQGPPGK------NGETGPQG--PPGPTGPGGDKGDTGPPGPQ-----GL 640
Query: 888 EPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFF 947
+ LP TG GPP GK P P+G P
Sbjct: 641 QGLP----GTG-GPPGENGKPG-----EPGPKGDAGAPGAP------------------- 671
Query: 948 PTMEEMFGGGAADDYGKAGPPEDEGDP--KAGAGPPPGPPAYDPYGPYCPGRASGAGPET 1005
G G A G+ GPP G P + GAGPP GP PG AG T
Sbjct: 672 ------GGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP--PGPPGAAG--T 721
Query: 1006 PGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFC 1065
PGL P E GL GP + P P P + G T PI
Sbjct: 722 PGLQGMPG-----------ERGGLGSPGP-KGDKGEPGGPGADGVPGKDGPRGPTGPI-- 767
Query: 1066 STKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLV 1125
PP + D+ + P LP +
Sbjct: 768 -------------------GPPGPAGQP---------GDKGEGGAPG--------LPGIA 791
Query: 1126 SSCRSRPALSPLGDIDFCPPNPG--PDGPRRRGRKPTKAKRDGP-PRPRGRPRIRPLEVP 1182
P SP + PP P P P + G K +R P + G P P
Sbjct: 792 G-----PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGP-------P 839
Query: 1183 TTAGPASASTPTDGAKKPRG----RGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGL 1238
AGP S P G P+G RG G A G R P P P G
Sbjct: 840 GVAGPPGGSGPA-GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898
Query: 1239 -GTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
G +G ++ K +A QP K G + PP
Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAG-------QPGEKGS----------PGAQGPP 941
Query: 1298 -----LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAES 1352
L AG+T + PP +P P P P GA GL G
Sbjct: 942 GAPGPLGIAGITGARG--LAGPPGMPGPRGSPGPQGVKGESGKP--GANGLSGERGPPGP 997
Query: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
+GL G + + LP + + A P G
Sbjct: 998 QGLP-GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056
Query: 1413 P------KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP------PT 1460
P + S P GP AP A P P P + T E K P
Sbjct: 1057 PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPG 1116
Query: 1461 PPPAPTPQPQP-----PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP--------- 1506
P +P P Q P P P P PS PP +S P P+ PP P
Sbjct: 1117 APGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP--GKDGTSGHPGPIGPPGPRGNRGERGS 1174
Query: 1507 ---PAMPSPPPPPPPAAAP 1522
P P P PP P AP
Sbjct: 1175 EGSPGHPGQPGPPGPPGAP 1193
Score = 127 bits (318), Expect = 1e-28
Identities = 265/988 (26%), Positives = 320/988 (32%), Gaps = 206/988 (20%)
Query: 137 PGSSTFPSSSALSAYQHPASF-------GSRPFPVPSS-LSLQDPPFSPPANGLLSPHDV 188
PG++ FP S PA G R P P Q PP P NG SP
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING--SPGGK 395
Query: 189 LHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDP-------PPPPRHL 241
+ P+ P P +G G GPAG A P R G +P P PR
Sbjct: 396 GEMGPAGIPGAPGLMGAR-----GPPGPAGANGA--PGLRGGAGEPGKNGAKGEPGPRGE 448
Query: 242 PTQFNLLASSSAAAAAAEQSSPQ---LYNFSGAAPGPPPPERALPRQDTVIKHYQRPASA 298
+ + A + SP GAA P P I + PA
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE 508
Query: 299 QPPPPP--PPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPG-----AGEPSKAGP 351
+ P P P A + P M P G+P P +G P GP
Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568
Query: 352 SG-----ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG----- 401
SG G G A G G GG GG P Q P K G+ G G
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP--QGPPGKNGETGPQGPPGPTGPG 626
Query: 402 ---GATRPPPPRS------TATPKCQSLGGPAAAYATGKAS--GAGGAGGQAYSPGQ--P 448
G T PP P+ T P ++ G P G A GA G G A +PG+ P
Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGEN-GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP 685
Query: 449 QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYG 508
GL G G GG + + GPP PP PGL + G+ G
Sbjct: 686 PGLAG----APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL--------QGMPGERGG 733
Query: 509 VQGEPYPGPAAHSQGLPTAS--PSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIR 566
+ G P P G P A P G + + G P G GG I
Sbjct: 734 L-GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAG 792
Query: 567 PLQSPPATGR--PPG-VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSE 623
P SP G PPG G PGAPG+ PG G GA G KG+G
Sbjct: 793 PRGSPGERGETGPPGPAGFPGAPGQN-----------GEPG-GKGERGAPGEKGEGGPPG 840
Query: 624 LLAGPGGP-PAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD--ASKGLGG---S 677
+ PGG PA P P G G G GAA ++GL G S
Sbjct: 841 VAGPPGGSGPAG--------------PPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGS 886
Query: 678 GGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEK----KKGPE 733
G GPPG K+ P T A G + + G+ EK +GP
Sbjct: 887 NGNPGPPGPSGSPGKDGPPG----PAGNTGAPGSPGVSGP-KGDAGQPGEKGSPGAQGPP 941
Query: 734 RGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV 793
G P G+A G + SP P +S +P +GL E G
Sbjct: 942 -GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG------- 993
Query: 794 LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH 853
PP PQ LP + A P + L RDG+P
Sbjct: 994 --PPGPQGLPGLAGTAGEPGRDGNPGSDGL---PGRDGSPGGKGD--------------- 1033
Query: 854 LRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPA--PGDTG----VGPPNSEGK 907
R P AP P PPG P+ PA GD G GP + G
Sbjct: 1034 -RGENGSPGAPGAPGHP----GPPG----------PVGPAGKSGDRGESGPAGPAGAPG- 1077
Query: 908 DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGP 967
PAG+ +P PQG + + + ER GAA G G
Sbjct: 1078 -PAGSRGAPGPQGPRGDKG-------------ETGER------------GAAGIKGHRGF 1111
Query: 968 PEDEGDP-------KAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPS 1020
P + G P + GA PGP P GP P G + G P PP
Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAG--PRGPVGPSGPPGKDGTSGHPG--PIGPPGPRG 1167
Query: 1021 TVNAEPLGLIQSGPHQAAPPPPPPPPPP 1048
P Q PP PP P P
Sbjct: 1168 NRGERGSEGSPGHPGQPGPPGPPGAPGP 1195
Score = 70.9 bits (172), Expect = 1e-11
Identities = 132/501 (26%), Positives = 160/501 (31%), Gaps = 109/501 (21%)
Query: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPA-NGLLSPHDVLHLKPSQ 195
PG + FP + + P G R P PP +G P +K +
Sbjct: 806 PGPAGFPGAPGQNG--EPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863
Query: 196 -APTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPP--DPPPPPRHLPTQFNLLASSS 252
+P P + GF G+ GP G PP G P D PP P A ++
Sbjct: 864 GSPGGPGAAGFP--GARGLPGPPGSNGNPGPPGPSGSPGKDGPPGP----------AGNT 911
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQH 312
A + S P+ P E+ P AQ PP P +
Sbjct: 912 GAPGSPGVSGPK-------GDAGQPGEKGSP-------------GAQGPPGAPGPLGIAG 951
Query: 313 YLSCGG--SYPSM-GHRANLACSPLGGGEPSPGA----GEPSKAGPSG-----ATAGASG 360
G P M G R + + G PGA GE GP G TAG G
Sbjct: 952 ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011
Query: 361 RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSL 420
R P + G G G GG G+ G A G P PP
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGD--------RGENGSPGAPGAPGHPGPPGPV-------- 1055
Query: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480
GPA SG G G A P +G GPQ +G G + + G P
Sbjct: 1056 -GPAGKSGDRGESGPAGPAG-APGPAGSRGAPGPQG-PRGDKGETGERGAAGIKGHRGFP 1112
Query: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
P P PG A Q G G P P G P+ P ++GH
Sbjct: 1113 GNPGAPGSPGPAGQQ------------GAIGSPGPAGPRGPVG-PSGPPGKDGTSGHP-- 1157
Query: 541 LSGHGGGWGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAP 598
G G GP G G E SP H G+P G PGAPG V A+A
Sbjct: 1158 --GPIGPPGPRGNRGERGSEGSPGH----------PGQPGPPGPPGAPGPCCGGVGAAA- 1204
Query: 599 FLAPPGAGSYAAGAGGYKGKG 619
AG GG K G
Sbjct: 1205 ----------IAGIGGEKAGG 1215
Score = 67.8 bits (164), Expect = 1e-10
Identities = 213/897 (23%), Positives = 262/897 (29%), Gaps = 174/897 (19%)
Query: 765 PPPPPTAQSTQ-----PTPHGLLLEAGGPDLP----LVLPPPPPQLLPSVLSHAPSPSPS 815
P PP Q Q P P G+ G P +P P PP + S + + SP
Sbjct: 95 PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154
Query: 816 ASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEES-- 873
V G P P PP PP P H S G P P P ++
Sbjct: 155 YDSYDVK--SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG-SPGYQGPPGEPGQAGP 211
Query: 874 LDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSIC 933
PPG GA+ P PA D G P G+ P P G K P +P
Sbjct: 212 SGPPGPP----GAIGPSGPAGKDGESGRPGRPGERGL-----PGPPGIKGPAGIP----G 258
Query: 934 FP--------DSLLQDEERSFFPTMEEMFG----GGAADDYGKAGPPEDEGDP------- 974
FP D ++ + P ++ G GA G G P + G P
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318
Query: 975 ---------KAGAGPPPGPPAYDPYGPYCPGRASGAGPE-------TPGLGLDPN----- 1013
G PPGPP + P PG GP PG +P
Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGF-PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377
Query: 1014 --KPPELPSTVNAEPLGLIQSGPH--------QAAPPPPPPPPPPPAPASEPKGGLTSPI 1063
+ P P +N P G + GP A PP P AP G
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKN 437
Query: 1064 FCSTKPKKLLKTSSFHL-----LRRRDPPFQTPKKLYAQEYEFEADEDKADV---PADIR 1115
+P + + + D +P + A A E A PA
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPA--- 494
Query: 1116 LNPRRLPDLVSSCRSRPALSPLGDIDFC--PPNPG-PDGPRRRGRK-----PTKAKRDGP 1167
P +P R A P G P G P GP RG P + GP
Sbjct: 495 -GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553
Query: 1168 PRPRGRPRIRPLEVPTTAGPASASTPTD-----GAKKPRGRGRGRGRKAEEAG----GTR 1218
P +G RP GP S P G P+G G+ E G G +
Sbjct: 554 PGSQGESG-RP-------GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605
Query: 1219 LEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHN--SLDSSLTREKIEAKIKEVEEKQPE 1276
P K + P G G GD L + K E K
Sbjct: 606 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665
Query: 1277 MKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPP 1336
G D G+R PP GL P P G P P
Sbjct: 666 GAPGAPGGKGDAGAPGERGPP----GLAGAPGLRGGAGPPGPEGGKGAAGP-------PG 714
Query: 1337 PSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDS--------V 1388
P GA G G L+ E GLG P P E + +P +
Sbjct: 715 PPGAAGTPG-LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSN--G 1446
+ D E + + P +AGP+ + G PGP PG P N G
Sbjct: 774 GQPGDKGEGGAPGL-----PGIAGPRGSPGERGE-----TGPPGPAGFPGAPGQNGEPGG 823
Query: 1447 TPEPPLLEEKPPPTPPP-APTPQPQPPPPPPPPQ--------------PALPSPPPLVAP 1491
E EK PP A P P PP PQ P L P
Sbjct: 824 KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGP 883
Query: 1492 TPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP----------LAAPPEEPAAPSPEDP 1538
S+ P P P P PP P AP A P E +P + P
Sbjct: 884 PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP 940
Score = 67.0 bits (162), Expect = 2e-10
Identities = 207/869 (23%), Positives = 256/869 (29%), Gaps = 152/869 (17%)
Query: 766 PPPPTAQSTQPT---PHGLLLEAGGPDLP-----LVLP--------PPPPQLLPSVLSHA 809
P PPTA + P P G + G P +P +P P PP + S +
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148
Query: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869
+ SP V G P P PP PP P H S G P P
Sbjct: 149 QNYSPQYDSYDVK--SGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG-SPGYQGPPGE 205
Query: 870 PEES--LDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927
P ++ PPG GA+ P PA D G P G+ P P G K P +
Sbjct: 206 PGQAGPSGPPGPP----GAIGPSGPAGKDGESGRPGRPGERGL-----PGPPGIKGPAGI 256
Query: 928 PLTSICFP--------DSLLQDEERSFFPTMEEMFG----GGAADDYGKAGPPEDEGDP- 974
P FP D ++ + P ++ G GA G G P + G P
Sbjct: 257 P----GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312
Query: 975 ---------------KAGAGPPPGPPAYDPYGPYCPGRASGAGPE-------TPGLGLDP 1012
G PPGPP + P PG GP PG +P
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGF-PGSPGAKGEVGPAGSPGSNGAPGQRGEP 371
Query: 1013 N-------KPPELPSTVNAEPLGLIQSGPHQAAPPP------PPPPPPPPAPASEPKGGL 1059
+ P P +N P G + GP P PP P A +GG
Sbjct: 372 GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGA 431
Query: 1060 TSPIFCSTKPKKLLKTSSFHL-------LRRRDPPFQTPKKLYAQEYEFEADEDKAD--- 1109
P K + + + D +P + A A E A
Sbjct: 432 GEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR 491
Query: 1110 VPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPG----PDGPRRRGR--KPTKAK 1163
PA P +P R A P G PG P GP RG P
Sbjct: 492 GPA----GPNGIPGEKGPAGERGAPGPAGPRG-AAGEPGRDGVPGGPGMRGMPGSPGGPG 546
Query: 1164 RDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAG----GTRL 1219
DG P P G P G P+G G+ E G G +
Sbjct: 547 SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606
Query: 1220 EPLKPLKIKLSVPKAGEGLGTSSGDA--ISGTDHNSLDSSLTREKIEAKIKEVEEKQPEM 1277
P K + P G G GD L + K E K
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666
Query: 1278 KSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337
G D G+R PP GL P P G P P P
Sbjct: 667 APGAPGGKGDAGAPGERGPP----GLAGAPGLRGGAGPPGPEGGKGAAGP-------PGP 715
Query: 1338 SGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDS--------VA 1389
GA G G L+ E GLG P P E + +P +
Sbjct: 716 PGAAGTPG-LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774
Query: 1390 KNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS--NGT 1447
+ D E + + P +AGP+ + G PGP PG P N G
Sbjct: 775 QPGDKGEGGAPGL-----PGIAGPRGSPGERG-----ETGPPGPAGFPGAPGQNGEPGGK 824
Query: 1448 PEPPLLEEKPPPTPP-PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP--- 1503
E EK PP A P P PP PQ +P P P
Sbjct: 825 GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE-----RGSPGGPGAAGFPGARG 879
Query: 1504 -PPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
P PP P PP P+ +P P PA
Sbjct: 880 LPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908
Score = 50.4 bits (119), Expect = 2e-05
Identities = 45/160 (28%), Positives = 49/160 (30%), Gaps = 42/160 (26%)
Query: 1415 DTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP 1474
D P+ P A P PP P P N G P K P PP P P P
Sbjct: 73 DCPNPEIPFGECCAVCPQPPTAPTRPP-NGQGPQGP-----KGDPGPPGIPGRNGDPGIP 126
Query: 1475 PPPPQPALPSPPPLVAPTPSSP------------------------PPPPLPPPPP---- 1506
P P P PP + P+ P P P PP PP
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPG 186
Query: 1507 ----PAMPSPP----PPPPPAAAPLAAPPEEPAAPSPEDP 1538
P P P PP P A + PP P A P P
Sbjct: 187 TSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGP 226
Score = 50.4 bits (119), Expect = 2e-05
Identities = 134/569 (23%), Positives = 166/569 (29%), Gaps = 88/569 (15%)
Query: 1301 AGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPP-------PSGAFGLGGALEAAESE 1353
AG P PP PP P P P +P PP PSG G GA+ +
Sbjct: 170 AGYPGPAGPPG--PPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227
Query: 1354 GLGLGCPSPCKRLDEELK-----RNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDP 1408
G P + + L + +P F + R+ ++ + A +
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287
Query: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
L G P GP AP G P LPG A N A
Sbjct: 288 GLPGENGAPGPMGPRGAPGER--GRPGLPGAAGARGNDG----------------ARGSD 329
Query: 1469 PQPPPPPPPPQPALPSPPPL---VAPTPS-----SPPPPPLPPPPPPAMPSPPPPPPPAA 1520
QP PP PP P P V P S +P P P A PP PP
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389
Query: 1521 APLAAPPEEPAAPSPEDPELPDTR-PLHLAKKQETAAVCGETDEEA--GESGGEGIFRER 1577
E A P P L R P A + G E G G G ER
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449
Query: 1578 DEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGD 1637
E I +P K + G++ P L G R + G G
Sbjct: 450 GEAGIPG--VPGAKG--EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 1638 AKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP 1697
A R P P G A P G P +
Sbjct: 506 AGER---------------------------GAPGPAGPRGAAGEPGRDGVPGGPGMRGM 538
Query: 1698 APPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPS-----LLRPVEKEKEKEKVTRGER 1752
P P P PP E+ P PP P P + P K + GE
Sbjct: 539 --PGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE- 595
Query: 1753 PLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAG 1812
RG G Q P ++ TG K PP + + L GG
Sbjct: 596 --RGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653
Query: 1813 G--GPPGSSSDSESSPGAP-SEDERAVPG 1838
G G PG D+ +PGAP + + PG
Sbjct: 654 GKPGEPGPKGDA-GAPGAPGGKGDAGAPG 681
Score = 43.1 bits (100), Expect = 0.003
Identities = 72/303 (23%), Positives = 96/303 (31%), Gaps = 39/303 (12%)
Query: 1297 PLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPH-------PPPSGAFGLGGALEA 1349
P AG P PP + S +G + P P P P P+GA G G
Sbjct: 373 PQGHAGAQGPPGPP-GINGSPGGKG-EMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430
Query: 1350 AESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPP 1409
A G P R E + + +P ++ + + A P
Sbjct: 431 AGEPGKNGAKGEPGPR-GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489
Query: 1410 L---AGPKDTSTPDGP--------PLAPAAA--------VPGPPPLPGLPSANSNGTPEP 1450
AGP GP P P A VPG P + G+P G+P
Sbjct: 490 FRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP-----GSPGG 544
Query: 1451 PLLEEKPPPTPPPAPTPQPQPPPPPPPP-QPALPSPPPLVAPTPSSPPPPPLPPPPPPAM 1509
P + KP P + +P PP P P QP + P P + P P
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP---GPKGNDGAPGKNGERGGPGG 601
Query: 1510 PSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESG 1569
P P PP P P P + + P L T GE + + GE G
Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE-NGKPGEPG 660
Query: 1570 GEG 1572
+G
Sbjct: 661 PKG 663
Score = 40.4 bits (93), Expect = 0.018
Identities = 79/324 (24%), Positives = 99/324 (30%), Gaps = 52/324 (16%)
Query: 1300 QAGLTPPLSPPKSVPPSVPA----RGLQPQPPATPAVPHPP----PSGAFGLGGAL---- 1347
QAG + P PP ++ PS PA +P P +P PP P+G G G
Sbjct: 208 QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267
Query: 1348 ------EAAESEGLGL----------GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKN 1391
E E+ GL G P P +R LP + + A+
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327
Query: 1392 RDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS-ANSNGTPEP 1450
D Q P G K P G P + A PG PG A + G P P
Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA--PGQRGEPGPQGHAGAQGPPGP 385
Query: 1451 PLLEEKPPPTPPPAPTPQPQPP---PPPPPPQPALPSPPPLVAPTPSSP-------PPPP 1500
P + P P P P PP PA + P + P P P
Sbjct: 386 PGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445
Query: 1501 LPPPPPPAMPSPP----------PPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAK 1550
+P P P P A L E AP P P+ P
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 1551 KQETAAVCGETDE-EAGESGGEGI 1573
E A AGE G +G+
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGV 529
Score = 36.6 bits (83), Expect = 0.26
Identities = 82/334 (24%), Positives = 111/334 (33%), Gaps = 62/334 (18%)
Query: 1144 PPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGR 1203
P +PG GP+ +P + G P G P PL + G + P G PRG
Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG--PLGIAGITGARGLAGPP-GMPGPRGS 970
Query: 1204 GRGRGRKAEE----AGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLT 1259
+G K E A G E P P+ GL ++G+ G D N L
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPP------GPQGLPGLAGTAGEP--GRDGNPGSDGLP 1022
Query: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPA 1319
+ G D ++G P G PP V P+ +
Sbjct: 1023 G-----------------RDGSPGGKGDRGENGSPGAP----GAPGHPGPPGPVGPAGKS 1061
Query: 1320 RGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPS 1379
PA PA P P+G+ G G +G E ++
Sbjct: 1062 GDRGESGPAGPAGA-PGPAGSRGAPGPQGPRGDKG----------ETGERGAAGIKGHRG 1110
Query: 1380 FSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPP-LAPAAAVPGPPPLPG 1438
F + + Q+ A+ P AGP+ P GPP + PGP PG
Sbjct: 1111 FPGNPGAPGSPGPAGQQG------AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164
Query: 1439 LPSAN-----SNGTPEPPLLEEKPPPTPPPAPTP 1467
P N S G+P P + PP PP AP P
Sbjct: 1165 -PRGNRGERGSEGSPGHP--GQPGPPGPPGAPGP 1195
Score = 33.9 bits (76), Expect = 1.7
Identities = 52/187 (27%), Positives = 63/187 (33%), Gaps = 35/187 (18%)
Query: 1678 GQAKNPVSAGGSSAP-PPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLR 1736
G A P AG P PP P P +P P Q + P PP PS
Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPS--G 225
Query: 1737 PVEKEKEKEKVTR-GERPL------------------RGERATSGRQTRPERSLATGQPA 1777
P K+ E + R GER L +G R GR + A G
Sbjct: 226 PAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG 285
Query: 1778 TSRLPKAR----PTKVKAEPPPKKRKKWLKEAG--GNATAGG-----GPPG--SSSDSES 1824
+ LP P + P + R AG GN A G GPPG ++
Sbjct: 286 ENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPG 345
Query: 1825 SPGAPSE 1831
SPGA E
Sbjct: 346 SPGAKGE 352
Score = 32.7 bits (73), Expect = 3.7
Identities = 40/140 (28%), Positives = 47/140 (33%), Gaps = 18/140 (12%)
Query: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCP 995
D ++ D++ P E FG A PP P G GP P DP P P
Sbjct: 63 DDIICDDQELDCPNPEIPFGECCAVC---PQPPTAPTRPPNGQGPQG--PKGDPGPPGIP 117
Query: 996 GRASGAG-PETPGLGLDPNKP------PELPSTVNAE------PLGLIQSGPHQAAPPPP 1042
GR G P PG P P P P + + G+ G P
Sbjct: 118 GRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAG 177
Query: 1043 PPPPPPPAPASEPKGGLTSP 1062
PP PP P S G SP
Sbjct: 178 PPGPPGPPGTSGHPGSPGSP 197
Score = 32.0 bits (71), Expect = 6.3
Identities = 38/143 (26%), Positives = 40/143 (27%), Gaps = 17/143 (11%)
Query: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSN-GTPEPPLLEEKP-------PPTPPP 1463
GP S P G P PGP G P N G P P + P P PP
Sbjct: 564 GPPGPSGPRGQP--GVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621
Query: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP- 1522
P PP L P P + P P P P A AP
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPG 681
Query: 1523 ------LAAPPEEPAAPSPEDPE 1539
LA P P PE
Sbjct: 682 ERGPPGLAGAPGLRGGAGPPGPE 704
Score = 31.6 bits (70), Expect = 8.3
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 2/95 (2%)
Query: 1411 AGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
AG K G P AP + PGP G + P P+ PP + P P
Sbjct: 1103 AGIKGHRGFPGNPGAPGS--PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI 1160
Query: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 1505
PP P + S P PP PP P P
Sbjct: 1161 GPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 122 bits (306), Expect = 4e-27
Identities = 130/435 (29%), Positives = 162/435 (37%), Gaps = 78/435 (17%)
Query: 1131 RPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRP-LEVP----TTA 1185
R ALS D P PG P R G PRP R RP E P ++A
Sbjct: 153 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212
Query: 1186 GPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDA 1245
S + P+ A++ G G R A + + PL S P SG +
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL-------SSP-------ARSGPS 258
Query: 1246 ISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTP 1305
GT S QP+ K L L+ + PP A P
Sbjct: 259 ARGTPRAPAHPS----------------QPKPKG------LQALRPPQVTPPRKDAA--P 294
Query: 1306 PLSPPKSVPPSVPA--RGLQPQ-PPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSP 1362
L P S P + P+ LQ Q PP PA PH +L + L L PSP
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPTLPATPH---------SSSLTCQLATPLPLAPPSP 345
Query: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGP 1422
+L+TLPS + + ++ + S L PPL+ P T P P
Sbjct: 346 ------SAPPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFLPSPPLS-PLATPPPQAP 397
Query: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEPP--------LLEE--KPPPTPP-PAPTPQPQP 1471
P + PP P P + TP P LL+ PPP+PP AP P
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 1472 PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531
PP P P +PP L AP PP PP PP P+ PP PP PLAAPP + A
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP----PLAAPPLQLA 513
Query: 1532 APSPEDPELPDTRPL 1546
P P+ P T PL
Sbjct: 514 KPPPQAPPALATPPL 528
Score = 112 bits (281), Expect = 3e-24
Identities = 166/647 (25%), Positives = 221/647 (34%), Gaps = 163/647 (25%)
Query: 948 PTMEEMFGGGAA---DDYGKAGPPEDEGD---------PKAGAGPPPGPPAYDPYGPYC- 994
P E G G A + +AGP G P +G G P GP
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
Query: 995 PGRASGAGPETP----GLGLDPNKPPELPSTVNAEPLGLIQSGPHQ-AAPPPPPPPPPPP 1049
PGRASG P GL + + A + +G + + P P P P
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 1050 APASEPKG---GLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADED 1106
A S G GL P S +P+ PP + P+K + E E
Sbjct: 177 ARRSRAAGTEVGLPRPA-PSARPR---------------PPTEGPRKSVSSASEHSTTEP 220
Query: 1107 KADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDG 1166
PA RR P + RPA L +P GP RG P
Sbjct: 221 S---PA-----ARRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPS 270
Query: 1167 PPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLK 1226
P+P+G +RP P P + P G PL
Sbjct: 271 QPKPKGLQALRP---PQVTPPRKDAAPALG------------------------PLS--S 301
Query: 1227 IKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFL 1286
L+ P L + + + T H+S SLT + +A+ L
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSS---SLTCQ--------------------LATPL 338
Query: 1287 DFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQ------PQPPATPAVPHPPPSGA 1340
PP Q +PP +PP S+ + LQ P PP +P PPP
Sbjct: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-PPPQAP 397
Query: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
L AL ++ PSP L L + S +++A + + +
Sbjct: 398 PAL--ALPPLQAP------PSP------PASPPLSPLATPSPQAPNALAVHL-----LQA 438
Query: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPT 1460
S PP+ P S P PP++P+A P P P L + PPL + PP+
Sbjct: 439 PFSPPPSPPVQAP--FSPPASPPVSPSATPPSQAP-PSLAA--------PPL---QVPPS 484
Query: 1461 PP------PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP--------- 1505
PP P+ TP PQ PPP P L PPP P ++PP LP PP
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 1506 ---------PPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543
P A P P PP AA L PP PA+P+ + P P T
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591
Score = 95.5 bits (236), Expect = 5e-19
Identities = 193/750 (25%), Positives = 249/750 (33%), Gaps = 173/750 (23%)
Query: 480 PQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSP 539
P+PP P PP T P L+ + G G P A G
Sbjct: 27 PRPPGSPRPPPPVT-----PAALR--VLGAAGAVGRKPLAERAG---------------- 63
Query: 540 ALSGHGGGWGPSSLGGGG--EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASA 597
G GG P S G ++ + P PPA+GR G P K S S+
Sbjct: 64 ---GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGR----GERAPPAKNTSPGPVSS 116
Query: 598 PFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSG 657
P A +G+ G G KG +E G + TE + + L A + TSG
Sbjct: 117 PGRA---SGTTRPGPLGQKGLRISAEETVARG----KATEAPK---RSALSAGARRDTSG 166
Query: 658 ADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAA 717
A S+ G G P + + R + S S + E + AA
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT--EPSPAA 224
Query: 718 LELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPP---PPPTAQST 774
++ P GG + S+ + A L + + P P A +
Sbjct: 225 -----------RRRPSAGGGLQRPASRSL---SSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 775 QPTPHGLLLEAGGPDLPLVLPP---PPPQLLPSVLSHAPSPSPSA--------------- 816
QP P GL +A P P V PP P L P S +PSPSA
Sbjct: 271 QPKPKGL--QALRP--PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 817 -SKVGVHLLEPATRDGAPQPPPPP-----PPPPPPMPLQLEAHLRSHGLEPA---APSPR 867
S + L P P P PP P PP P Q L S L+ PSP
Sbjct: 327 SSSLTCQLATPLPL-APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385
Query: 868 LRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFV 927
L P + PP A L AL PL PP+ P +PSPQ AP +
Sbjct: 386 LSPLAT-PPPQAPPAL--ALPPLQ--------APPSPPASPPLSPLATPSPQ---APNAL 431
Query: 928 PLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP---PPGP 984
+ + P S P ++ F A+ + P + P A P PP P
Sbjct: 432 AVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Query: 985 PAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPP 1044
PA P P TP PP+ P + A PL L + PP
Sbjct: 486 PASPPMSPSA----------TP--------PPQAPPPLAAPPLQLAK-----------PP 516
Query: 1045 PPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEAD 1104
P PPA A+ P L SP ++S + PP Q P L A +
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ---- 572
Query: 1105 EDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKR 1164
VP P SP PP PGPD G + T A
Sbjct: 573 -----VPPS------------------PPASPTLQAPRRPPTPGPD-TSVSGPRLTLALA 608
Query: 1165 DGPPRPRGRPRIRPLEVPTTAGPASASTPT 1194
GPP P R L P AG +S++T T
Sbjct: 609 PGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Score = 89.4 bits (220), Expect = 3e-17
Identities = 210/852 (24%), Positives = 263/852 (30%), Gaps = 163/852 (19%)
Query: 209 AGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSA-------------AA 255
AG PA P P PG P PPPP P +L ++ A
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPV--TPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 256 AAAEQSSPQL-----YNFSGAAPGPPPP-----ERALPRQDTVIKHYQRPASAQPPPPPP 305
A +S+P+ S P PP ERA P ++T P A P
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 306 PAHALQHYLSC-------------------------------GGSYPSMGHRANLACSPL 334
P +S G P+M R+ A + +
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 335 GGGEPSPGA-GEPSKAGPSGATAGASGRA-TGPEAAGGGGAGGGGGGYRPIIQSPGYKTG 392
G P+P A P GP + + AS + T P A GGG RP +S
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 393 KGGYGAAAGGATR--PPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQG 450
A +G + R P P + PK + L T A A G S P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS--SPLA 305
Query: 451 LLGPQAYGQGFGGGQAQDLSKAPSYSGG---------PPQPPSGPPPPGLATCQSYSPDQ 501
P A Q QA A +S P PPS PP L T S
Sbjct: 306 TPSPSAALQ----SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361
Query: 502 LQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASP 561
P A S G PT + S+ SP LS +A P
Sbjct: 362 -------------PSQATTSLGSPTLQATHSFLP--SPPLS--------PLATPPPQAPP 398
Query: 562 SHIIRPLQSPPATGRPPGVG-----SPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYK 616
+ + PLQ+PP+ P + SP AP L+ L APF PP A
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAPFSPPPSPPVQAP------ 451
Query: 617 GKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGG 676
+ P PP + + +PP + V A
Sbjct: 452 --------FSPPASPPVSPSATP--------PSQAPPSLAAPPLQVPPSPPASPPMSPSA 495
Query: 677 SGGAGGPP---GTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPE 733
+ PP P +LAK PQ + T + A G P
Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQ---APPALATPPLQALPSPPASFPGQAPFSPSASLPM 552
Query: 734 RGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPP--PTAQSTQ--PTPHGLLLEAGGPD 789
TP A V L A L + PP PP PT Q+ + PTP G GP
Sbjct: 553 SPLATPPPQAPPV---------LAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR 602
Query: 790 LPLVL---PPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM 846
L L L PPPPP PS P + +S E D P+ PPP
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 662
Query: 847 PLQLEAHLRSHGLEP-----AAPSPRLRPEESLDPPGAMQELLGAL-----EPLPPAPG- 895
S G P AP L P PG+ L E PAPG
Sbjct: 663 LAACHPAAWSRGPAPPLAFRGAPGAPL-PWPPATGPGSADGLCTIYETEGPESATPAPGA 721
Query: 896 -DTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQD-EERSFFPTMEEM 953
D G P S GK AGA S + K R L S++Q R+ E
Sbjct: 722 LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEG 781
Query: 954 FGGGAADDYGKA 965
GG+ G A
Sbjct: 782 AAGGSGGGPGGA 793
Score = 83.6 bits (205), Expect = 2e-15
Identities = 173/731 (23%), Positives = 239/731 (32%), Gaps = 162/731 (22%)
Query: 58 SYATNHHPAGLSGLF----DTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQF 113
S T P G GL +T + P S ++ + ++ GP PG + ++ +
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 114 RSPSWQTAMHTPGPT----------ELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP 163
R+ + + P P+ +S A S+T PS +A + P++ G P
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP---AARRRPSAGGGLQRP 237
Query: 164 VPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLA----------GGGV 213
SLS P S PA P + P+ P G + L
Sbjct: 238 ASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 214 LGPAGLGP-----------AQTPPYRPGPPDP-------------PPPPRHLPTQFNLLA 249
LGP P +Q PP P P PP P L
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 250 SSSA---AAAAAEQSSPQLYNFSGAAPGPP------PPERALPRQDTVIKHYQRPAS--A 298
S A + A SP L P PP PP +A P + Q P S A
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA--LALPPLQAPPSPPA 413
Query: 299 QPP------PPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPS 352
PP P P +AL +L P SP SP A PS+A PS
Sbjct: 414 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473
Query: 353 GATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPP--PR 410
A + P + + P + +P + K PPP P
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK------------PPPQAPP 521
Query: 411 STATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA-------YGQGFGG 463
+ ATP Q+L P A++ G A P P PQA Q
Sbjct: 522 ALATPPLQALPSPPASF-----PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 464 GQAQDLSKAP----------SYSG---------GPPQPP--------SGPPPPGLATCQS 496
A +AP S SG GPP PP SGP G ++ +
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636
Query: 497 YSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGG-----GWGPS 551
+P++L+G G +G P ++ L P+ ++S G +P L+ G W P+
Sbjct: 637 STPEELRGYDSGPEGGAAASPPPDAE-LAACHPA-AWSRGPAPPLAFRGAPGAPLPWPPA 694
Query: 552 SLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAG 611
+ G G A I + P + PG PG PG A
Sbjct: 695 T--GPGSADGLCTIYETEGPESATPAPGALDPG----------------PSPGTSGGKAA 736
Query: 612 AGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADAS 671
AG G S A G P + ++QHLL + A+G G G
Sbjct: 737 AGAGAGASSRSPKQARLGELPLGALQAS--VVQHLLSRTL--LLAAAEGAAGGSG----- 787
Query: 672 KGLGGSGGAGG 682
GG GGA G
Sbjct: 788 ---GGPGGAEG 795
Score = 80.1 bits (196), Expect = 2e-14
Identities = 199/868 (22%), Positives = 262/868 (30%), Gaps = 201/868 (23%)
Query: 817 SKVGVHLLEPATRDGA---PQPPPPPPPPPP--PMPLQLEAHLRSHGLEPAAP------- 864
+K G PA R P+PP P PPPP P L++ + G +P A
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 865 ------SPRLRPEESLDP----PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
+PR P S P + G E PPA +T GP +S G+ A
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK-NTSPGPVSSPGR--ASGTT 124
Query: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP 974
P P G K R + EE G A + K G
Sbjct: 125 RPGPLGQKGLRI----------------------SAEETVARGKATEAPKRSALS-AGAR 161
Query: 975 KAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGP 1034
+ +GP PG P+ P R+ AG E +GL P P P + S
Sbjct: 162 RDTSGPTPGTPS-----PAMARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSAS 213
Query: 1035 HQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKL 1094
+ P P P+ GGL P + L +S+ P +P +
Sbjct: 214 EHSTTEPSPAARRRPSAG----GGLQRPA------SRSLSSSA--------TPLSSPARS 255
Query: 1095 YAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCR-SRPALSPLGDIDFCPPNPGPDGPR 1153
P L R P + + + PAL PL P+P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS----- 310
Query: 1154 RRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEE 1213
++A P P L P P S S P P +
Sbjct: 311 --AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 1214 AGGTRLE---------PLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIE 1264
G L+ PL PL P+A L A + S L
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATP--PPQAPPALALPPLQAPPSPPASPPLSPLATPS-- 424
Query: 1265 AKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKS--------VPPS 1316
P+ + L S PP+ QA +PP SPP S PPS
Sbjct: 425 ----------PQAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPSQAPPS 473
Query: 1317 VPARGLQ--PQPPATPAVPH---PPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELK 1371
+ A LQ P PPA+P + PPP L + L L P P +
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-------APPLQLAKPPP-QAPPALAT 525
Query: 1372 RNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP-----DGPPLAP 1426
L+ LPS + S S S +S L PP P + P PP +P
Sbjct: 526 PPLQALPSPPA----SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581
Query: 1427 AAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP------------- 1473
P PP PG P + +G L PPP P +P+ P
Sbjct: 582 TLQAPRRPPTPG-PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 1474 ----------------PPPPPQPAL---------PSPPPLVAPTPSSPPP-PPLPPP--- 1504
PPP + A P+PP P +P P PP P
Sbjct: 641 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
Query: 1505 -----------PPPAMPSP---PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAK 1550
P A P+P P P P + A A S P+ L L
Sbjct: 701 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 760
Query: 1551 KQETAA--------VCGETDEEAGESGG 1570
Q + + + AG SGG
Sbjct: 761 LQASVVQHLLSRTLLLAAAEGAAGGSGG 788
Score = 57.4 bits (137), Expect = 1e-07
Identities = 127/580 (21%), Positives = 179/580 (30%), Gaps = 81/580 (13%)
Query: 1302 GLTPPLSPPKSVPP---SVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLG 1358
G T P S P++ P +R +PPA+ PP+ G + G
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP----- 1413
P K L E++VA+ + + SA+SA +GP
Sbjct: 127 GPLGQKGL--------------RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
Query: 1414 --------KDTSTPDGPPLAPAAAVPGPP---PLPGLPSANSNGTPEP-PLLEEKPP--- 1458
+ T G P +A P PP P + SA+ + T EP P +P
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 1459 ---------------PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVA--PTPSSPPPPPL 1501
P PA + P P P+ P P L A P +PP
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 1502 PPPPPPAMPSPPPPPPPAAAPLA-APPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE 1560
P P SP P P+AA + APP PA P PL LA +A +
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352
Query: 1561 T--------DEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQ 1612
T +A S G + F+ P LA + PP + L
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFL---PSPPLSPLATPPPQAPPAL--ALPPLQA 407
Query: 1613 KFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPV 1672
+P S A N ++ + V+ P P
Sbjct: 408 PPSPPASPPLSPLATPS------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Query: 1673 PVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732
P P A PP PA PP + PP P + +PP P
Sbjct: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 1733 SLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAE 1792
+L P + + G+ S + P LAT P + A +V
Sbjct: 522 ALATP-----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576
Query: 1793 PP--PKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPS 1830
PP P + G T+ GP + + + P PS
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
Score = 46.2 bits (108), Expect = 3e-04
Identities = 86/317 (27%), Positives = 114/317 (35%), Gaps = 54/317 (17%)
Query: 100 PQPGPSASSLLSQFRSPSWQT--AMHTPGPTELFIS--GALPGSSTFPSSSALSAYQHPA 155
PQ P ++ Q P Q A+ TP P + S + PG + F S++L
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLAT 557
Query: 156 SFGSRPFPVPSSLSLQDPPFSPPANGLLS----------------PHDVLHLKPSQAPTV 199
P PV ++ LQ PP SPPA+ L P L L P P
Sbjct: 558 PPPQAP-PVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP- 614
Query: 200 PSSLGFERLAGGGVLGPAGLG---PAQTPPYRPGPPD----PPPPPRHLPTQFNLLASSS 252
PS L+G + G + P + Y GP PPP L A+
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-------AACH 667
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQR--PASAQPPP---PPPPA 307
AA + + P + + AP P PP D + Y+ P SA P P P P+
Sbjct: 668 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 727
Query: 308 HALQHYLSCGGSYPSMGHR----ANLACSPLGGGEPSPGAGEPSK----AGPSGATAGAS 359
+ G+ R A L PLG + S S+ A GA G+
Sbjct: 728 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787
Query: 360 GRATGPEAAGGGGAGGG 376
G GP A GGG GG
Sbjct: 788 G---GPGGAEGGGVTGG 801
Score = 45.4 bits (106), Expect = 6e-04
Identities = 90/360 (25%), Positives = 121/360 (33%), Gaps = 73/360 (20%)
Query: 1490 APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL----AAPPEEPAAPSPEDPELPDTRP 1545
A TP++ P L P PP + P PPPP PAA + A +P A
Sbjct: 14 ARTPAARAPGLLTPRPPGS-PRPPPPVTPAALRVLGAAGAVGRKPLA------------- 59
Query: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQT-GREPPPIW 1604
E AG GG I E RA S + + PP
Sbjct: 60 -----------------ERAGGIGGATI----PESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 1605 RVQKALLQKFT---PEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRV 1661
R ++A K T P G+ LG G + + + K+ +
Sbjct: 99 RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 158
Query: 1662 CARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPET--PEKTTSEKPPEQTP 1719
AR+ P A+ +AG P AP+ P+P T P K+ S T
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 1720 ETAMPEPPAPEKPS----LLRPVEKEKEKEKVTRGERPLRGERATSGRQTR--PERSLAT 1773
E P P A +PS L RP + ++ PL A SG R P
Sbjct: 219 E---PSPAARRRPSAGGGLQRPASR-----SLSSSATPL-SSPARSGPSARGTPRAPAHP 269
Query: 1774 GQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDE 1833
QP L RP +V PP+K +A GP SS + SP A + +
Sbjct: 270 SQPKPKGLQALRPPQV---TPPRK----------DAAPALGPLSSSPLATPSPSAALQSQ 316
Score = 34.7 bits (78), Expect = 0.98
Identities = 35/133 (26%), Positives = 41/133 (30%), Gaps = 13/133 (9%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP-----KPETPEKTTSEKPPEQTPETAMP 1724
P P+ PV A PP PA P +P TP TS P T A
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 1725 EPPAPEK--PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP 1782
PP P + S L + T LR G + PE A P + L
Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR------GYDSGPEGGAAASPPPDAELA 664
Query: 1783 KARPTKVKAEPPP 1795
P P P
Sbjct: 665 ACHPAAWSRGPAP 677
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 122 bits (306), Expect = 4e-27
Identities = 93/263 (35%), Positives = 106/263 (40%), Gaps = 45/263 (17%)
Query: 1296 PPLYQAGLTPPLSPPKS---VPPSVPARGLQPQPPATPA-VPHPPPSGAFGLGGALEAAE 1351
PPL AG+ PP P + PP +P G+ P PP A +P PPP G+
Sbjct: 979 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPP 1035
Query: 1352 SEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA 1411
G G+ P P LP + PPL
Sbjct: 1036 LPGAGIPPPPP--------------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1081
Query: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP 1471
G P PPL P A +P PPPLPG+ G P PP L P PPP P P
Sbjct: 1082 G---AGIPPPPPL-PGAGIPPPPPLPGV------GIPPPPPLPGAGIPPPPPLPGAGIPP 1131
Query: 1472 PPP-------PPPPQPALPSPPPLVAPTPSSPPPPPL-----PPPPP-PAMPSPPPPPPP 1518
PPP PPPP P + PPP P PPPPPL PPPPP P + PPPPP P
Sbjct: 1132 PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1191
Query: 1519 AAAPLAAPPEEPAAPSPEDPELP 1541
+ PP P A P P LP
Sbjct: 1192 GVG-IPPPPPLPGAGIPPPPPLP 1213
Score = 122 bits (305), Expect = 5e-27
Identities = 92/267 (34%), Positives = 103/267 (38%), Gaps = 53/267 (19%)
Query: 1296 PPLYQAGLTPPLSPPKS---VPPSVPARGLQPQPPATPA-VPHPPPSGAFGLGGALEAAE 1351
PPL A + PP P + +PP +P G+ P PP A +P PPP G+
Sbjct: 946 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---PPPP 1002
Query: 1352 SEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA 1411
G G+ P P LP + PPL
Sbjct: 1003 LPGAGIPPPPP--------------LPGAGIPPPPPLP-----------GAGIPPPPPLP 1037
Query: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLPGL-----PSANSNGTPEPPLLEEKPPPTPPPAPT 1466
G P PPL P A +P PPPLPG P G P PP L P PPP P
Sbjct: 1038 G---AGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1093
Query: 1467 PQPQPPPP-------PPPPQPALPSPPPLVAPTPSSPPPPPL-----PPPPPPAMPSPPP 1514
PPPP PPPP P PPP P PPPPPL PPPPP PP
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 1515 PPPPAAAPLAAPPEEPAAPSPEDPELP 1541
PPP A + PP P A P P LP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLP 1180
Score = 121 bits (304), Expect = 6e-27
Identities = 96/270 (35%), Positives = 104/270 (38%), Gaps = 57/270 (21%)
Query: 1296 PPLYQAGLTPPLSPPKS-----VPPSVPARGLQPQPPATPA-VPHPPPSGAFGLGGALEA 1349
PPL + PP PP PP +P G+ P PP A +P PPP L GA
Sbjct: 900 PPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP-----LPGAAIP 954
Query: 1350 AESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPP 1409
G G P P LP + PP
Sbjct: 955 PPPPLPGAGIPLP------------PPLPGAGIPPPPPLP-----------GAGIPPPPP 991
Query: 1410 LAGPKDTSTPDGPPLAPAAAVPGPPPLPGL-----PSANSNGTPEPPLLEEKPPPTPPPA 1464
L G P PPL P A +P PPPLPG P G P PP L P PPP
Sbjct: 992 LPG---AGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Query: 1465 PTPQPQPPPP-------PPPPQPALPSPPPLVAPTPSSPPPPPL-----PPPPP-PAMPS 1511
P PPPP PPPP P PPP P PPPPPL PPPPP P +
Sbjct: 1048 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107
Query: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541
PPPPP P A + PP P A P P LP
Sbjct: 1108 PPPPPLPGAG-IPPPPPLPGAGIPPPPPLP 1136
Score = 115 bits (288), Expect = 4e-25
Identities = 91/263 (34%), Positives = 99/263 (37%), Gaps = 77/263 (29%)
Query: 1296 PPLYQAGLTPPLSPPKSVPPSVPARG---LQPQPPATPAVPHPPPSGAFGLGGALEAAES 1352
PP G+T P P ++P P +G L P PP P PPP G G L
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG-AGILPLPPL 937
Query: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
G G+ P P PPL G
Sbjct: 938 PGAGI--PPP---------------------------------------------PPLPG 950
Query: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
+ P PPL P A +P PPPLPG G P PP L P PPP P PP
Sbjct: 951 ---AAIPPPPPL-PGAGIPLPPPLPGA------GIPPPPPLPGAGIPPPPPLPGAGIPPP 1000
Query: 1473 PP-------PPPPQPALPSPPPLVAPTPSSPPPPPLPP---PPPPAMPS----PPPPPPP 1518
PP PPPP P PPP P PPPPPLP PPPP +P PPPP P
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
Query: 1519 AAAPLAAPPEEPAAPSPEDPELP 1541
A P PP P A P P LP
Sbjct: 1061 AGIP--PPPPLPGAGIPPPPPLP 1081
Score = 108 bits (269), Expect = 7e-23
Identities = 103/320 (32%), Positives = 115/320 (35%), Gaps = 52/320 (16%)
Query: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
PPPPPP T PT + P + PPPP LP P P P A G+
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA---GILP 933
Query: 824 LEPATRDGAPQPPPPPP---PPPPPMP---LQLEAHLRSHGLEPAAPSPRLRPEESLDPP 877
L P G P PPP P PPPPP+P + L L G+ P P P P
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLP 993
Query: 878 GAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS 937
GA + P PP PG PP G AG P G P PL
Sbjct: 994 GA------GIPPPPPLPGAGIPPPPPLPG---AGIPPPPPLPGAGIPPPPPLPG------ 1038
Query: 938 LLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPP---AYDPYGPYC 994
+ P + G G G P GAG PP PP A P P
Sbjct: 1039 -------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
Query: 995 PGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP------PPPPP 1048
PG P PG+G+ P PP LP P L P PPPPP PPPPP
Sbjct: 1092 PGAGIPPPPPLPGVGIPP--PPPLPGAGIPPPPPL----PGAGIPPPPPLPGAGIPPPPP 1145
Query: 1049 ------PAPASEPKGGLTSP 1062
P P P G+ P
Sbjct: 1146 LPRVGIPPPPPLPGAGIPPP 1165
Score = 104 bits (260), Expect = 8e-22
Identities = 66/181 (36%), Positives = 82/181 (45%), Gaps = 22/181 (12%)
Query: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLP 1437
P S E + + + ++ + PPL + +S+ G + P P PPPLP
Sbjct: 829 PPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP----PPPPPLP 884
Query: 1438 GL--PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP------PQPALPS---PP 1486
G+ P+ S P+PP L+ PPP P P PPPPP P P LP PP
Sbjct: 885 GMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPP 944
Query: 1487 PLVAPTPSSPPPPPLP------PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
P P + PPPPPLP PPP P PPPPP P A + PP P A P P L
Sbjct: 945 PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPL 1003
Query: 1541 P 1541
P
Sbjct: 1004 P 1004
Score = 102 bits (253), Expect = 5e-21
Identities = 114/344 (33%), Positives = 129/344 (37%), Gaps = 62/344 (18%)
Query: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLV------LPPPPPQLLPSVLSHAPSPSPSAS 817
PPPPPP + P P L G LPL +PPPPP LP P P P A
Sbjct: 909 PPPPPPLPGAGIPPPPPL---PGAGILPLPPLPGAGIPPPPP--LPGAAIPPPPPLPGA- 962
Query: 818 KVGVHLLEPATRDGAPQPPP--------PPP------PPPPPMP---LQLEAHLRSHGLE 860
G+ L P G P PPP PPP PPPPP+P + L G+
Sbjct: 963 --GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 861 PAAPSPRLRPEESLDPPGA----MQELLGA-LEPLPPAPGDTGVGPPN---SEGKDP--- 909
P P P PGA L GA + P PP PG G+ PP G P
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPP 1079
Query: 910 ---AGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD--YGK 964
AG P G P PL + P + P + G G
Sbjct: 1080 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 965 AGPPEDEGDPKAGAGPPPG-PPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
AG P P+ G PPP P A P P PG P PG+G+ P PP LP
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP--PPPLPGVGI 1195
Query: 1024 AEPLGLIQSGPHQAAPPPPPPP----PPPPAPASEPKG-GLTSP 1062
P L P PPPPP P PP PAP P G G+ P
Sbjct: 1196 PPPPPL----PGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Score = 100 bits (248), Expect = 2e-20
Identities = 107/331 (32%), Positives = 120/331 (36%), Gaps = 50/331 (15%)
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV----LPPPPPQLLPSVLSHAPSP 812
G + PPPP P A P P L AG LP + +PPPPP LP P P
Sbjct: 904 GTEMLPPPPPPLPGAGIPPPPP---LPGAGILPLPPLPGAGIPPPPP--LPGAAIPPPPP 958
Query: 813 SPSASKVGVHLLEPATRDGAPQPPPPPP---PPPPPMP---LQLEAHLRSHGLEPAAPSP 866
P A G+ L P G P PPP P PPPPP+P + L G+ P P P
Sbjct: 959 LPGA---GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PGA + P PP PG PP G AG P G P
Sbjct: 1016 GAGIPPPPPLPGA------GIPPPPPLPGAGIPPPPPLPG---AGIPPPPPLPGAGIPPP 1066
Query: 927 VPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPP- 985
PL P + P + G G G P GAG PP PP
Sbjct: 1067 PPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 986 --AYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP 1043
A P P PG P P +G+ P PP LP P L P PPPPP
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPP--PPPLPGAGIPPPPPL----PGAGIPPPPP 1178
Query: 1044 ------PPPPP------PAPASEPKGGLTSP 1062
PPPPP P P P G+ P
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP 1209
Score = 93.6 bits (231), Expect = 2e-18
Identities = 106/367 (28%), Positives = 125/367 (34%), Gaps = 81/367 (22%)
Query: 765 PPPPPTAQS-------------TQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPS 811
PP PP A+S P + L++ P + PPPPP LL S P
Sbjct: 767 PPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPG 826
Query: 812 PSPSAS------KVGVHLLEPATRDGAPQPPPPP----------------PPPPPPMPLQ 849
P S H + A ++ P PPP PPPPPP+P
Sbjct: 827 SQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM 886
Query: 850 LEAHLRS---------HGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG 900
L S G E P P P + PP + + PLPP PG G+
Sbjct: 887 TVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPG--AGILPLPPLPG-AGIP 943
Query: 901 PPNSEGKDPAGAYRSPSP---QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGG 957
PP P A P P G P +P I P L + P + G G
Sbjct: 944 PPPPL---PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL----PGAGIPPPPPLPGAG 996
Query: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPP---AYDPYGPYCPGRASGAGPETPGLGLDPNK 1014
G P GAG PP PP A P P PG P PG G+ P
Sbjct: 997 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-- 1054
Query: 1015 PPELPSTVNAEPLGLIQSG-------PHQAAPPPPP------PPPPP------PAPASEP 1055
PP LP P L +G P PPPPP PPPPP P P P
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114
Query: 1056 KGGLTSP 1062
G+ P
Sbjct: 1115 GAGIPPP 1121
Score = 89.7 bits (221), Expect = 3e-17
Identities = 88/287 (30%), Positives = 106/287 (36%), Gaps = 70/287 (24%)
Query: 1296 PPLYQAGLTPPLSPPKS---VPPSVPARGLQPQPPATPA-VPHPPPSGAFGLGGALEAAE 1351
PPL AG+ PP P + PP +P G+ P PP A +P PPP G+
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP---PPPP 1112
Query: 1352 SEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA 1411
G G+ P P LP + A PP
Sbjct: 1113 LPGAGIPPPPP--------------LPGAGIPPPPPLP-------------GAGIPPPPP 1145
Query: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLP--------GLPSANSNGTPEPPLLEEKPPPTPPP 1463
P+ P PPL P A +P PPPLP LP G P PP L P PPP
Sbjct: 1146 LPR-VGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGV---GIPPPPPLPGVGIPPPPP 1200
Query: 1464 APTPQPQPPPPPP----PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP------- 1512
P PPPP P PP PA P PP P PPPP LP PP +P
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPP----PGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256
Query: 1513 -------PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQ 1552
PPP P L ++ + P +P P +PL+ + Q
Sbjct: 1257 PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP-MKPLYWTRIQ 1302
Score = 59.7 bits (143), Expect = 3e-08
Identities = 132/490 (26%), Positives = 156/490 (31%), Gaps = 81/490 (16%)
Query: 145 SSALSAYQHPASFGSRPFPVPSSL--SLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSS 202
S L ++Q P S+P P PS L + Q P S P + + + H + S + +S
Sbjct: 795 SVQLDSHQ-PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSH-EHSVSSAFKNS 852
Query: 203 LGFERLAGGGVLGPAGLGPAQTPPYRPG-----PPDPPPPPRHLPTQFNLLASSSAAAAA 257
+ P L ++ PG PP PP P +PT +
Sbjct: 853 CN--------IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQG 904
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG 317
E P GA PPPP LP ++ P + PPPPP P A+
Sbjct: 905 TEMLPPPPPPLPGAGIPPPPP---LPGAG-ILPLPPLPGAGIPPPPPLPGAAIPP----- 955
Query: 318 GSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGG---GAG 374
P A + P P PGAG P GA G P G G
Sbjct: 956 ---PPPLPGAGIPLPP-----PLPGAGIPPPPPLPGA-----GIPPPPPLPGAGIPPPPP 1002
Query: 375 GGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTA----TPKCQSLGGPAAAYATG 430
G G P PG G G PPPP A P G P G
Sbjct: 1003 LPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
Query: 431 KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPP----SGP 486
G P P + P G G L A G PP PP P
Sbjct: 1061 --------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA----GIPPPPPLPGVGIP 1108
Query: 487 PPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGG 546
PPP L P L G G P P P G+P P P L G G
Sbjct: 1109 PPPPLPGAGIPPPPPLPG-----AGIP-PPPPLPGAGIPPPPPLPRVGIPPPPPLPG-AG 1161
Query: 547 GWGPSSLGGGGEASPSHI----IRPLQSPPATGRPPGVGSPGA------PGKYLSSVLAS 596
P L G G P + I P P G PP PGA P + A
Sbjct: 1162 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAP 1221
Query: 597 APFLAPPGAG 606
AP L PPG G
Sbjct: 1222 APPLPPPGTG 1231
Score = 45.4 bits (106), Expect = 6e-04
Identities = 35/90 (38%), Positives = 41/90 (45%), Gaps = 18/90 (20%)
Query: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLV-LPPPPPQLLPSVLSHAPSPSPSASKVGVH 822
PPPP P A P P + P LP V +PPPPP LP P P P +G+
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGAGIPPPPPLPG---MGI- 1217
Query: 823 LLEPATRDGAPQPPPPPP----PPPPPMPL 848
AP PP PPP PPPP +P+
Sbjct: 1218 -------PPAPAPPLPPPGTGIPPPPLLPV 1240
Score = 43.9 bits (102), Expect = 0.002
Identities = 45/158 (28%), Positives = 52/158 (32%), Gaps = 41/158 (25%)
Query: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA---------PTPQPQPPPP 1474
L P +PG PP P P A S P+ E P PT PPP
Sbjct: 757 LPPVDGLPGRPPCP--PGAESG--PQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP 812
Query: 1475 PPP-------PQPALPSPPPLVAPTPSS---------------PPPPPLP----PPPPPA 1508
PP QP P + +S P PPPLP P
Sbjct: 813 PPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG 872
Query: 1509 MPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
+ PPPPPP P P P+ P+ P L T L
Sbjct: 873 LGMVPPPPPP--LPGMTVPTLPSTAIPQPPPLQGTEML 908
Score = 40.0 bits (92), Expect = 0.023
Identities = 128/613 (20%), Positives = 196/613 (31%), Gaps = 118/613 (19%)
Query: 1178 PLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEG 1237
P EV GP G + R GR E A G A +G
Sbjct: 138 PFEVTGPGGP--------GPAEARVGGRPIAEDVETAAG-----------------AQDG 172
Query: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
TSSG S TD S S+ +E + + I++ Q + + L+ ++
Sbjct: 173 QRTSSG---SDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQ------LQLQQQQQQ 223
Query: 1298 LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGL 1357
G P +PP +V PQP A + F LG + A E+ G
Sbjct: 224 QQLQGAEEPAAPPTAV---------SPQPGAFLGLDR------FLLGPSGGAGEAPG--- 265
Query: 1358 GCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTS 1417
S D E +++ DL ES+++ PP G S
Sbjct: 266 -----------------------SPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVS 302
Query: 1418 -TPDGPPLAPAA-------AVPGPPPLPGLPSANSN----GTPEPPLLEEKPPPTPPPAP 1465
P P PAA A P P PG +A + G + E+ P +P
Sbjct: 303 EAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSP 362
Query: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP-------PP 1518
+ P PQ L P A P +P LP P P+ P P
Sbjct: 363 GEEWAPEVGEDAPQ-RLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKT 421
Query: 1519 AAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQET--AAVCGETDEEAGESG-GEGIFR 1575
L++P P+ + P + L++ T A+V + + G G+ R
Sbjct: 422 TTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSR 481
Query: 1576 ERD---EFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFT--PEIKDG-QRQFCATS 1629
D E R + L+ G V AL K + P DG Q F +
Sbjct: 482 SADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRT 541
Query: 1630 NYLGYFGDAKNRYQRLYVKFLENVNKKDYV---RVCARKPWHRPPVPVRRSGQAKNPVSA 1686
F +N KF + + C R+P ++ S +
Sbjct: 542 LLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTW 601
Query: 1687 GGSSAP-----------PPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLL 1735
S P P + P+ P + P++ + E ++A+ E P ++
Sbjct: 602 AAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAVQ 661
Query: 1736 RPVEKEKEKEKVT 1748
+ V K + + T
Sbjct: 662 KEVVDMKSEGQAT 674
Score = 38.1 bits (87), Expect = 0.088
Identities = 86/341 (25%), Positives = 107/341 (31%), Gaps = 47/341 (13%)
Query: 342 GAGEPSKAGPSGATAGASG----RATGPEAAGGGGAGGGGGGYRPIIQSPGYKT------ 391
G G GP A G +A G GGGG GGGG + +S +
Sbjct: 20 GGGAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNLR 79
Query: 392 -------GKGGYG---------AAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKA--- 432
GKG G A G T TP A T A
Sbjct: 80 IRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPF 139
Query: 433 --SGAGGAG-GQAYSPGQP-----QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS 484
+G GG G +A G+P + G Q GQ G D+ S+ Q
Sbjct: 140 EVTGPGGPGPAEARVGGRPIAEDVETAAGAQD-GQRTSSGSDTDIY---SFHSATEQEDL 195
Query: 485 GPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA-SPSLSYSTGHSPALSG 543
Q QLQ QL Q + A PTA SP G L G
Sbjct: 196 LSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLG 255
Query: 544 HGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPP 603
GG G + E + S + +S A R P P +PG S S P P
Sbjct: 256 PSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ--QPPSPGGLPVSEAPSLPAAQPA 313
Query: 604 GAGSYAAGAGGYKGKGDGSELLAGP---GGPPAERTEDEEF 641
S ++ A + G G E P G E E++ F
Sbjct: 314 AKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAF 354
Score = 36.6 bits (83), Expect = 0.26
Identities = 19/58 (32%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ R G P G PPP P P P PP P +P PP
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199
Score = 35.8 bits (81), Expect = 0.44
Identities = 20/63 (31%), Positives = 23/63 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P+ +G P G PPP P P P PP P +P PAP
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223
Query: 1730 EKP 1732
P
Sbjct: 1224 PLP 1226
Score = 35.4 bits (80), Expect = 0.57
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 977 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1034
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 988 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1056
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1078
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1089
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Score = 35.0 bits (79), Expect = 0.75
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPP 1122
Score = 34.7 bits (78), Expect = 0.98
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 955 PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1012
Score = 34.7 bits (78), Expect = 0.98
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133
Score = 34.7 bits (78), Expect = 0.98
Identities = 18/58 (31%), Positives = 20/58 (34%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ G P G PPP P P P PP P +P PP
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155
Score = 34.3 bits (77), Expect = 1.3
Identities = 47/202 (23%), Positives = 63/202 (31%), Gaps = 45/202 (22%)
Query: 402 GATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGF 461
GA P P + +P+ + G + G + GAG A G SP Q L
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLG-LDRFLLGPSGGAGEAPG---SPDTEQALSA-------- 275
Query: 462 GGGQAQDLSKAPSYSGGPPQPPSGPPPPG---------LATCQSYSPDQLQGQLYGVQGE 512
LS P P+ P PP PG L Q + D +
Sbjct: 276 -------LSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF----- 323
Query: 513 PYP--GPAAHSQGLPTASPSLSYSTGHSPAL-----SGHGGGWGPSSLGGGGEASPSHI- 564
P+P GP + G P + G A G W P GE +P +
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEV----GEDAPQRLG 379
Query: 565 IRPLQSPPATGRPPGVGSPGAP 586
P + P PG+P
Sbjct: 380 EEPEEEAQGPDAPAAASLPGSP 401
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
Score = 33.9 bits (76), Expect = 1.7
Identities = 18/58 (31%), Positives = 21/58 (36%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P P P PP P +P PP
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Score = 33.1 bits (74), Expect = 2.8
Identities = 21/60 (35%), Positives = 24/60 (40%), Gaps = 4/60 (6%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAP--APPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP P+ +G P G PPP P A PP P P PP P +P PP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP--LPGAGIPPPP 979
Score = 33.1 bits (74), Expect = 2.8
Identities = 22/72 (30%), Positives = 25/72 (34%), Gaps = 4/72 (5%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPA----PPPKPETPEKTTSEKPPEQTPETAMPE 1725
PP P+ G P G PPP P P P P P T PP P + P
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL 1245
Query: 1726 PPAPEKPSLLRP 1737
P +L P
Sbjct: 1246 LPQVGSSTLPTP 1257
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 4/62 (6%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAP--PPKPETPEK--TTSEKPPEQTPETAMPE 1725
PP P+ G P G PPP P PP P P + PP P T +P
Sbjct: 1175 PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP 1234
Query: 1726 PP 1727
PP
Sbjct: 1235 PP 1236
Score = 32.3 bits (72), Expect = 4.9
Identities = 17/57 (29%), Positives = 20/57 (35%)
Query: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
P P+ +G P G PPP P P P PP P +P PP
Sbjct: 967 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1023
Score = 32.0 bits (71), Expect = 6.3
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 16/68 (23%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP+P S SS+ P PPP P P T P TA+P+PP
Sbjct: 859 PPLPCTES-----------SSSMPGLGMVPPPPPPLPGMTVPT-----LPSTAIPQPPPL 902
Query: 1730 EKPSLLRP 1737
+ +L P
Sbjct: 903 QGTEMLPP 910
Score = 31.6 bits (70), Expect = 8.3
Identities = 29/97 (29%), Positives = 33/97 (34%), Gaps = 14/97 (14%)
Query: 269 SGAAPGPPPPERALPR-QDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRA 327
+G APG P E+AL D P Q PP P G P +
Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSP-------------GGLPVSEAPS 306
Query: 328 NLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATG 364
A P PS A +AGP AGA R G
Sbjct: 307 LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAG 343
Score = 31.6 bits (70), Expect = 8.3
Identities = 31/107 (28%), Positives = 36/107 (33%), Gaps = 17/107 (15%)
Query: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
PPPP P A P P L G P P PPP +P P P G L
Sbjct: 1197 PPPPLPGAGIPPPPP---LPGMGIPPAPAPPLPPPGTGIP--------PPPLLPVSGPPL 1245
Query: 824 LEPATRDGAPQP------PPPPPPPPPPMPLQLEAHLRSHGLEPAAP 864
L P P PPP P + + + R +EP P
Sbjct: 1246 LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
sapiens]
Length = 1688
Score = 121 bits (304), Expect = 6e-27
Identities = 374/1503 (24%), Positives = 455/1503 (30%), Gaps = 318/1503 (21%)
Query: 158 GSRPFP-VPSSLSLQDPPFSPPANGLLSPHDVLHLK----PSQAPTVPSSLGFERLAGG- 211
G R FP P LQ PP P G+ + + P P P G + L G
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G+ GP G PP PG PP PP + N+ + + Q
Sbjct: 189 GIPGPIG------PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQ------- 235
Query: 272 APGPPPPERALPRQDTVIK-HYQR-----PASAQPPPPP----PPAHALQHYLSCGGSYP 321
GPP P + Q I +Q+ P PP PP PP GG
Sbjct: 236 --GPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP-------GGEKG 286
Query: 322 SMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--GASGRATGPEAAGGGGAGGGGGG 379
G + GEP G+P K G +G G G P G G G G
Sbjct: 287 EKGEQ----------GEPGK-RGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335
Query: 380 YRP------IIQSPGYKTG-----KGGYGAAA--------GGATRPPPPRSTATPKCQSL 420
P +I PG TG KG G G PP P +
Sbjct: 336 TGPPGPPGLVIPRPG--TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393
Query: 421 GGPAAAYATGKASGAGGAGGQAYSPGQPQGLLG-PQAYG-QGFGGGQAQDLSKAPSY-SG 477
G P G+ G G S P GL G P A G G G + +
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP 453
Query: 478 GPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHS--QGLPTASPSLSYST 535
GPP PP P GL Q D+ + G GP GLP SL +
Sbjct: 454 GPPGPPGSPGDKGLQGEQGVKGDK-GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512
Query: 536 GHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLS--SV 593
G G GP L G P A G P GS G PG L+ +
Sbjct: 513 QKGE--KGQAGATGPKGLPG--------------IPGAPGAPGFPGSKGEPGDILTFPGM 556
Query: 594 LASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPP 653
L PGA G G G+ DG L GP G P T E PP
Sbjct: 557 KGDKGELGSPGAPGLP-GLPGTPGQ-DGLPGLPGPKGEPGGITFKGE---------RGPP 605
Query: 654 RTSGADGLVGEDGAAD----------ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSV 703
G GL G G KG+ G G G PG P K DP +
Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP--KGDPGQ------ 657
Query: 704 IRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKS 763
++ + L GR + + G GL + G +
Sbjct: 658 -----TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG--IPGSKGEPGIPGIGLPG 710
Query: 764 PPPP--------PPTAQSTQ--------PTPHGLLLEAGGPDLPLVLPPPPPQLL----- 802
PP P PP A T P P G G P L PP PP L
Sbjct: 711 PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGA 770
Query: 803 --PSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP---------PPMPLQLE 851
P P P + G+ L D P P P PP PP P +
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830
Query: 852 AHLRSHGL-----EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG 906
+ GL E P P LD PG E +P APG +GPP S G
Sbjct: 831 GPIGQPGLHGIPGEKGDPGP-----PGLDVPGPPGER--GSPGIPGAPGP--IGPPGSPG 881
Query: 907 -KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD--YG 963
AGA P +G P P L RS P ++ DD G
Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPP-----GPPGPLGIPGRSGVPGLK-------GDDGLQG 929
Query: 964 KAGPPEDEGDPKAGAGPP--PGPPAYDPYGPYCPGRASGAGPE-TPGLGLDPNKPPELPS 1020
+ G P G+ K G P PGPP GP P G + PGL P +P
Sbjct: 930 QPGLPGPTGE-KGSKGEPGLPGPP-----GPMDPNLLGSKGEKGEPGL-------PGIPG 976
Query: 1021 TVNAEPLGLIQSGPHQAA----PPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTS 1076
+ + P Q P P PP P P + GL P L T
Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG-------PPGLKGTI 1029
Query: 1077 SFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSP 1136
D F P+ + E + VP + LP + P +S
Sbjct: 1030 G-------DMGFPGPQGV-------EGPPGPSGVPG--QPGSPGLPGQKGD-KGDPGISS 1072
Query: 1137 LGDIDFCPPNPGPDG-------PRRRGRK-----PTKAKRDGPPRPRGRPRIRPLE-VPT 1183
+G P PGP G P G K P G P +G+P + P
Sbjct: 1073 IG----LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128
Query: 1184 TAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVP--KAGE----G 1237
GP S P P G G G E KP + + P + GE G
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188
Query: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
G + G D L + P+ + GF G + PP
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG-----PKGEPGFHGF------PGVQGPP 1237
Query: 1298 LYQAGLTPPLSPPKSVP-PSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGL 1355
P L PK P P P P P +P P P G G GG + G
Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGP-----PGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPG- 1291
Query: 1356 GLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKD 1415
+ L LP D+ + + ++ DP L G
Sbjct: 1292 ---------------QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG---DPGLPGVPG 1333
Query: 1416 TSTPDGPPLAPAAAVP-------GPPPLPGLPSANSN-----GTPEPPLLEEKPPPTPPP 1463
GP P +A P GPP PGLP + G PP + +P P
Sbjct: 1334 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1393
Query: 1464 APT-PQPQPPPPPPPPQPALPSPPPLVAP--------TPSSPPPPPLPPPPPPAMPSPPP 1514
P PQ P P PP P P P P L PP P PP
Sbjct: 1394 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP 1453
Query: 1515 PPP 1517
PP
Sbjct: 1454 GPP 1456
Score = 114 bits (285), Expect = 1e-24
Identities = 353/1357 (26%), Positives = 428/1357 (31%), Gaps = 305/1357 (22%)
Query: 342 GAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG 401
G SK SG G G P G G G G P PG + KG G
Sbjct: 31 GCSPGSKCDCSGIK-GEKGERGFPGLEGHPGLPGFPGPEGP----PGPRGQKGDDGIPGP 85
Query: 402 GAT---RPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP--QGLLGP 454
R PP P TP + G A G G G+ PG P GL GP
Sbjct: 86 PGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145
Query: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514
G G + + S S GP P P PPG+ QG L G G
Sbjct: 146 PG-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGI-----------QG-LPGPTG--I 190
Query: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPAT 574
PGP P P L G P L G G G + G GE + LQ PP
Sbjct: 191 PGPIG-----PPGPPGLMGPPG-PPGLPGPKGNMGLNFQGPKGEKGE----QGLQGPPG- 239
Query: 575 GRPPGV--------------GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG-KG 619
PPG G G PG P PPG GG KG KG
Sbjct: 240 --PPGQISEQKRPIDVEFQKGDQGLPGD------RGPP--GPPGIRGPPGPPGGEKGEKG 289
Query: 620 DGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGG 679
+ E G G P + E+ + P P G G GE G D KG G G
Sbjct: 290 EQGE--PGKRGKPGKDGENGQ---------PGIPGLPGDPGYPGEPGR-DGEKGQKGDTG 337
Query: 680 AGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALEL-GLGRLKEKKKGPERGGET 738
GPPG + R + G + L GL K ++ P G +
Sbjct: 338 PPGPPGLV---------------IPRPGTGITIGEKGNIGLPGLPGEKGERGFP--GIQG 380
Query: 739 PEGLATSVVHYGAGAKELGAFLQKSPPPPP--PTAQSTQ----------PTPHGLLLEAG 786
P GL GA +G PP PP P + + P P GL + G
Sbjct: 381 PPGLPGP-----PGAAVMG------PPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429
Query: 787 GPDLPLVLPPPPPQLLPS---VLSHAPSPSPSASKVGVHLLEPATRD------------- 830
P LP P P + PS P P S G+ + D
Sbjct: 430 APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489
Query: 831 -GAPQPPPPPPPPPPPMPLQLEAHLRSHGLE-----------------PAAPSPRLRPEE 872
G P P P P PP L G P P + P +
Sbjct: 490 SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD 549
Query: 873 SLDPPGAMQEL--LGA-----LEPLPPAPGDTGV-GPPNSEGKDPAGAYRSPSPQGTKAP 924
L PG + LG+ L LP PG G+ G P +G +P G + +G + P
Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG-EPGGI----TFKGERGP 604
Query: 925 RFVP-LTSICFPDSLLQDEERSFFPT--MEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP 981
P L + P ++ F P + E G A + G+ G P +GDP P
Sbjct: 605 PGNPGLPGL--PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662
Query: 982 -----PGPPAYD-----PYGPYCPGRASGAG-------PETPGLGLD----PNKPPELPS 1020
PG P D P P PG+ G P PG+GL P P +P
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722
Query: 1021 TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHL 1080
A P + PP PP P P EP L P L L
Sbjct: 723 PPGAP------GTPGRIGLEGPPGPPGFPGPKGEPGFALPGP-----PGPPGLPGFKGAL 771
Query: 1081 LRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDI 1140
+ D F P + K DV + + P P L P + G
Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL-------PGIGVQGPP 824
Query: 1141 DFCPPN-PGPDG-------PRRRGRK-PTKAKRDGPPRPRGRPRIRPLEVPTTAGPASAS 1191
PP PGP G P +G P GPP RG P I P GP
Sbjct: 825 G--PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI-----PGAPGPI-GP 876
Query: 1192 TPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDH 1251
+ G G G K E P PL I G S + G D
Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP----------GRSGVPGLKGDDG 926
Query: 1252 NSLDSSL---TREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLS 1308
L T EK + M + S K K P L G+ P +S
Sbjct: 927 LQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS-----KGEKGEPGL--PGI-PGVS 978
Query: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGL-----GLGCPSP 1362
PK +P QP P +P PP P G GL G GL +G P P
Sbjct: 979 GPKGY-QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037
Query: 1363 CKRLDEELKRNLETLPSFSS--DEEDSVAKNRDLQESISSAISALDDPPLAGPKD----T 1416
+ +E P S + S + IS++ P L GPK
Sbjct: 1038 ---------QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1088
Query: 1417 STPDGPPLAPAAAVPGPPPLPGLPSANSN-------GTPEPPLLE--EKPPPTP--PPAP 1465
P P + + PG P LPG P A GTP PP + PP P P P
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1148
Query: 1466 TP-----QPQPPPPP----PPPQPALPSPPPLVA----PTPSSPPPPPLP-------PPP 1505
P P P PP P Q +P P P +P PP LP
Sbjct: 1149 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208
Query: 1506 PPAMPSPPPPPPPAAAP-------LAAPPEEPAAPSP 1535
P +P P P P P + PP P +P P
Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245
Score = 108 bits (271), Expect = 4e-23
Identities = 296/1126 (26%), Positives = 361/1126 (32%), Gaps = 251/1126 (22%)
Query: 125 PGPTELFISGALPGSS-TFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPF--SPPANG 181
PGP L I PG+ T + P G R FP +Q PP PP
Sbjct: 339 PGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFP-----GIQGPPGLPGPPGAA 391
Query: 182 LLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHL 241
++ P P P G E G + GP GL P PGPP P P H+
Sbjct: 392 VMGPPG-----PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGP--HI 444
Query: 242 PTQFNLL--------ASSSAAAAAAEQS-----SPQLYNFSGAAPGPPPPERALPRQDTV 288
P + S EQ +N G PP + LP
Sbjct: 445 PPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504
Query: 289 I--------KHYQRPASAQPP---PPPPPAHALQHYLSCGG------SYPSM-GHRANLA 330
K + A A P P P A + G ++P M G + L
Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELG 564
Query: 331 CSPLGGGEPS-PGA----GEPSKAGPSGATAGAS--GRATGPEAAGGGGAGGGGGGYRPI 383
SP G P PG G P GP G G + G P G G G G P
Sbjct: 565 -SPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPP 623
Query: 384 IQSPGYKTGKGGYGAAAGGATRP--PPPRSTATPKCQSLGGPAAAYATGKASGAG----- 436
P G+ G AG +P P P+ G P G+ G
Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683
Query: 437 GAGGQAYSPGQPQ----------GLLGPQAYGQGFGGGQAQDLSKAPSYSG-----GPPQ 481
G GQ PG P GL GP +GF G AP G GPP
Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPG-PKGFPGIPGPP--GAPGTPGRIGLEGPPG 740
Query: 482 PPSGPPP---PGLATCQSYSPDQLQG--QLYGVQGEP-YPGPAAHSQGLPTASPSLSYST 535
PP P P PG A P L G G +G+ +PGP P L
Sbjct: 741 PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG-----PPGRTGLDGLP 795
Query: 536 GHSPALSGHG--GGWGPSSLGG---GGEASPSHIIRPLQSPPATG--------RPPGVGS 582
G + +G G GP L G G P I P+ P G PPG+
Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855
Query: 583 PGAPGKYLSSVLASAPF-LAPPGAGSYA--AGAGGYKGKGDGSELLAGPGGPPAER---- 635
PG PG+ S + AP + PPG+ AGA G+ G G + GP GPP
Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT-KGEMGMMGPPGPPGPLGIPG 914
Query: 636 -------TEDEEFLIQHLLQAPSPPRTS-GADGLVGEDGAADASKGLGGSGGAGGPPGTP 687
D+ Q L P+ + S G GL G G D + L GS G G PG P
Sbjct: 915 RSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPN--LLGSKGEKGEPGLP 972
Query: 688 YELAKEDPQRYHLQSVIRTSASLDEGATAAL-ELGLGRLKEKKKGPERGGET----PEGL 742
P+ Y D G + GL K P G+ P GL
Sbjct: 973 GIPGVSGPKGYQ-------GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025
Query: 743 ATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV----LPP-P 797
++ G Q PP P+ QP GL + G P + LP P
Sbjct: 1026 KGTIGDMGFPGP------QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLP 1079
Query: 798 PPQLLPSVLSHAPSPSPSASKVGVHLLE--PATRDGAPQPPPP--PPPPPPPMPLQLEAH 853
P+ P + + +P S VG L P T QP P P P PP P +
Sbjct: 1080 GPKGEPGLPGYPGNPGIKGS-VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138
Query: 854 LRSHGL--------------EPAAPSPRLRPEE-------------------SLDPPG-- 878
+ GL +P P + +P + + PPG
Sbjct: 1139 PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLP 1198
Query: 879 --AMQELLGALEPLPPAPGDTGV----------------GPPNSEGKDPAGAYRSPSPQG 920
+ Q+ G L +P PG G GPP S G G +P PQG
Sbjct: 1199 GLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQG 1258
Query: 921 TKA-PRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP--KAG 977
P F L P L + GG + G G P G P K
Sbjct: 1259 PPGRPGFQGLPGPEGPPGLPGN--------------GGIKGEKGNPGQPGLPGLPGLKGD 1304
Query: 978 AGPP-----PGPPAY-----DPYGPYCP---------GRASGAGPE-TPGLGLDPNKPPE 1017
GPP PG P DP P P G AGPE PGL + P PP
Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL-IGPPGPPG 1363
Query: 1018 LPSTV--------NAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
LP +A P G I P P P P P P P
Sbjct: 1364 LPGPSGQSIIIKGDAGPPG-IPGQPGLKGLPGPQGPQGLPGPTGPP 1408
Score = 89.0 bits (219), Expect = 4e-17
Identities = 162/639 (25%), Positives = 206/639 (32%), Gaps = 130/639 (20%)
Query: 125 PGPTELFISG-----------ALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQD 172
PGP L + G PG P S L P G+ FP + +
Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL-----PGKAGASGFPGTKGEMGMMG 902
Query: 173 PPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGP 231
PP P G+ P ++ VP G + L G G+ GP G ++ P PGP
Sbjct: 903 PPGPPGPLGI----------PGRSG-VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP 951
Query: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291
P P P NLL S E+ P L G + P + LP
Sbjct: 952 PGPMDP--------NLLGSKG------EKGEPGLPGIPGVSG--PKGYQGLPGDPG---- 991
Query: 292 YQRPASAQPPPPPPPAH----------------ALQHYLSCGGSYPSMGHRANLACSPLG 335
Q S QP P PP L+ + G G S +
Sbjct: 992 -QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050
Query: 336 GGEPSPGA-GEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKG 394
G SPG G+ G G ++ GP+ G G G + + PG G
Sbjct: 1051 GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLP-GLP 1109
Query: 395 GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGP 454
G A G P P + P + + GP G G GG PG P
Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP------ 1163
Query: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPS--GPPPPGLATCQSYSPDQLQGQLYGVQGE 512
G G QD P+ G P P P PPGL D G L G+ G
Sbjct: 1164 -----GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD---GGLPGIPGN 1215
Query: 513 P-YPGPAAHS--------QGLP----TASPSLSYSTGHS--------PALSGHGGGWGPS 551
P PGP QG P + P+L G+ P G G GP
Sbjct: 1216 PGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPP 1275
Query: 552 SLGGGG-----EASPSHIIRP-LQSPPATGRPPGV-GSPGAPGKYLSSVLASAPFLAPPG 604
L G G + +P P L PPG+ G+PG PG L+ + PG
Sbjct: 1276 GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG--LNGMKGDPGLPGVPG 1333
Query: 605 AGSYAAGAGGYKGKG-DGSELLAGPGGPPA-ERTEDEEFLIQHLLQAPSPPRTSGADGLV 662
+G G +G L GP GPP + +I+ P P G GL
Sbjct: 1334 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1393
Query: 663 GEDG--------------AADASKGLGGSGGAGGPPGTP 687
G G + G G+GG G PG P
Sbjct: 1394 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP 1432
Score = 87.8 bits (216), Expect = 1e-16
Identities = 212/880 (24%), Positives = 263/880 (29%), Gaps = 137/880 (15%)
Query: 260 QSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGS 319
+ P L F G GPP P + D I P + PP P G
Sbjct: 56 EGHPGLPGFPGPE-GPPGPRGQ--KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH 112
Query: 320 YPSMGHRANLACSPLGGGEPSPGA-GEPSKAGPSGATA--GASGRATGPEAAGGGGAGGG 376
+ G + C+ G PG+ G P GP G G G + G G
Sbjct: 113 DGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172
Query: 377 GGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAG 436
G P PG + G G G P PP P L GP G
Sbjct: 173 PGYPGP----PGIQ-GLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227
Query: 437 GAGGQAYS-PGQPQGLLGPQA------YGQGFGGGQAQDLSKAPSYSGGPPQPPSGPP-- 487
G Q P P G + Q + +G G P GPP PP G
Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287
Query: 488 -----PPGLATCQSYSPDQLQGQLYGVQGEP-YPGPAAHSQGL-------PTASPSLSYS 534
PG + Q + G+ G+P YPG P P L
Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347
Query: 535 TGHSPALSGHGGGWGPSSLGG--GGEASPSHIIRPLQSPPATGRPPG---VGSPGAPGKY 589
+ G G G L G G P +Q PP PPG +G PG PG
Sbjct: 348 RPGTGITIGEKGNIGLPGLPGEKGERGFPG-----IQGPPGLPGPPGAAVMGPPGPPG-- 400
Query: 590 LSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQA 649
PPG G G G+ G+ L GP GP + + +
Sbjct: 401 FPGERGQKGDEGPPGIS--IPGPPGLDGQ-PGAPGLPGPPGPAGPHIPPSDEICEP--GP 455
Query: 650 PSPPRTSGADGLVGEDGA----ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR 705
P PP + G GL GE G D G+G GPPG P P
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTG-ISGPPGQPGLPGLPGPPG-------- 506
Query: 706 TSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPP 765
LG +K + + G P+GL GA F
Sbjct: 507 ---------------SLGFPGQKGEKGQAGATGPKGLPGI-----PGAPGAPGFPGSKGE 546
Query: 766 PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLE 825
P G L G P LP + P LP + P P G+
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGL------PGPKGEPGGITFKG 600
Query: 826 PATRDGAPQPP----------PPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
G P P PP PP P+ + + + +P P P+ P +++
Sbjct: 601 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660
Query: 876 PPGAMQELLG--------ALEPLPPAPGDTGV-GPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PG L G L P PG G+ G P S+G+ P P G K
Sbjct: 661 QPGK-PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG 719
Query: 927 VPLTSICFPDSLLQDEERSFF---PTMEEMFGGGAADDYGKAGPPEDEGDP--KAGAGP- 980
+P P R P G + GPP G P K GP
Sbjct: 720 IP-----GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 981 -------PPGPPAYD-------PYGPYCPGRASG--AGPETPGLGLD-PNKPPELPSTVN 1023
PPGPP P G P G P PG+G+ P PP +P +
Sbjct: 775 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834
Query: 1024 AEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPI 1063
L I PP P PP S G PI
Sbjct: 835 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI 874
Score = 56.6 bits (135), Expect = 2e-07
Identities = 47/150 (31%), Positives = 53/150 (35%), Gaps = 29/150 (19%)
Query: 1410 LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS-------ANSNGTPEPPL------LEEK 1456
L GP GP P A+PGPP PGLP G P PP L+
Sbjct: 735 LEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGL 794
Query: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP--PPPLPPPPPPAMPSPPP 1514
P P P QP P PP P + PP PP P P+ P +P
Sbjct: 795 PGPKGDVGPNGQPGPMGPPGLPGIGVQGPP--------GPPGIPGPIGQPGLHGIPGEKG 846
Query: 1515 PPPPAAAPLAAPPEE------PAAPSPEDP 1538
P P + PP E P AP P P
Sbjct: 847 DPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876
Score = 53.1 bits (126), Expect = 3e-06
Identities = 135/569 (23%), Positives = 176/569 (30%), Gaps = 109/569 (19%)
Query: 1300 QAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGC 1359
Q GL P L PK P + +G + PP P +P P G G G G G
Sbjct: 580 QDGL-PGLPGPKGEPGGITFKG-ERGPPGNPGLPGLP--GNIGPMGPP--------GFGP 627
Query: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
P P + P + D I+ P L G
Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGDP-----------GQTITQPGKPGLPGNPGRDGD 676
Query: 1420 DGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP-----PAPTPQPQPP-- 1472
G P P +PG P LPG+P S G P P + PP P P P P P
Sbjct: 677 VGLPGDPG--LPGQPGLPGIPG--SKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGR 732
Query: 1473 -----PPPPPPQPALPSPPPLVAPTPSSPPPPP-----LPPPPPPAMPSPP-PPPPPAAA 1521
PP PP P P P P PP P L P P PP PP
Sbjct: 733 IGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792
Query: 1522 PLAAPPEEPAAPSPEDPELPDTRP-LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEF 1580
L P + P P P + + + G G+ G GI E+ +
Sbjct: 793 GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI----GQPGLHGIPGEKGDP 848
Query: 1581 VIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEI--KDGQRQFCATSNYLGYFGDA 1638
D+P R P I + +P + K G F T +G G
Sbjct: 849 GPPGLDVPGPP----GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPP 904
Query: 1639 KNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAP-PPKAP 1697
PP P+ G++ P G P P
Sbjct: 905 G------------------------------PPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934
Query: 1698 APPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGE 1757
P T EK + +P +P PP P P+LL K ++ E G + G
Sbjct: 935 GP-----TGEKGSKGEP-------GLPGPPGPMDPNLLG--SKGEKGEPGLPGIPGVSGP 980
Query: 1758 RATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPP----PKKRKKWLKEAGGNATAG- 1812
+ G P + +GQP P + P P K + + G G
Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040
Query: 1813 GGPPGSSS--DSESSPGAPSE-DERAVPG 1838
GPPG S SPG P + ++ PG
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069
Score = 52.8 bits (125), Expect = 3e-06
Identities = 119/451 (26%), Positives = 142/451 (31%), Gaps = 115/451 (25%)
Query: 1144 PPNPGPDGPRR-RGRKPTKAKRDGPPRPRGRPRIR-PLEVPTTAG-PASASTPT-DGAKK 1199
P PGP+GP RG+K DG P P G IR P +P G P P DGA
Sbjct: 62 PGFPGPEGPPGPRGQKGD----DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 117
Query: 1200 PRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLT 1259
P+G G K E R P P L P G+ + G + + SSL
Sbjct: 118 PQGIPGCNGTKGE-----RGFPGSPGFPGLQGPPGPPGI-----PGMKGEPGSIIMSSLP 167
Query: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSV-PPSVP 1318
P+ G+ PP Q GL P P + PP P
Sbjct: 168 G--------------PKGNPGYPG------------PPGIQ-GLPGPTGIPGPIGPPGPP 200
Query: 1319 ARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGL-GCPSPCKRLDEELKRNLETL 1377
P PP P P G GL E GL G P P ++ E+ KR ++
Sbjct: 201 GLMGPPGPPGLPG-----PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ-KRPIDV- 253
Query: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAA--AVPGPPP 1435
F ++ + PP GP P GPP G P
Sbjct: 254 -EFQKGDQ---------------GLPGDRGPP--GPPGIRGPPGPPGGEKGEKGEQGEPG 295
Query: 1436 LPGLPSANS-NGTPEPPLLEEKPP-PTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT- 1492
G P + NG P P L P P P + Q PP P L P P T
Sbjct: 296 KRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITI 355
Query: 1493 --------------------PSSPPPPPLPPPPPPAMPSPPPPP-------------PPA 1519
P PP LP PP A+ PP PP PP
Sbjct: 356 GEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415
Query: 1520 AAPLAAP-----PEEPAAPSPEDPELPDTRP 1545
+ P P P P P P P P
Sbjct: 416 ISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446
Score = 50.8 bits (120), Expect = 1e-05
Identities = 173/710 (24%), Positives = 215/710 (30%), Gaps = 163/710 (22%)
Query: 957 GAADDYGKAGPPEDEGDPKAGAGPP-----------PGPPAYD----PYG-PYCPGRASG 1000
G D G GPP PK GPP PG P +D P G P C G
Sbjct: 75 GQKGDDGIPGPP----GPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGE 130
Query: 1001 AG-PETPGL-GLD-PNKPPELPSTVNAEPLGLIQS---GPH-----------QAAPPP-- 1041
G P +PG GL P PP +P + EP +I S GP Q P P
Sbjct: 131 RGFPGSPGFPGLQGPPGPPGIPG-MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189
Query: 1042 ------PPPPP----PPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP 1091
PP PP PP P G F K +K L PP Q
Sbjct: 190 IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK----GEQGLQGPPGPPGQIS 245
Query: 1092 KKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDG 1151
++ + EF+ + +P D R P R P P G G
Sbjct: 246 EQKRPIDVEFQKGDQ--GLPGD------RGPPGPPGIRGPPG-----------PPGGEKG 286
Query: 1152 PRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTP-TDGAKKPRGRGR----- 1205
+ +P K + G G+P I L P P DG K +G
Sbjct: 287 EKGEQGEPGKRGKPGKDGENGQPGIPGLP----GDPGYPGEPGRDGEKGQKGDTGPPGPP 342
Query: 1206 -------GRGRKAEEAGGTRLEPLKPLKIKLSVP--KAGEGLGTSSGDAISGTDHNSLDS 1256
G G E G L L K + P + GL G A+ G
Sbjct: 343 GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFP 402
Query: 1257 SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP----LSPPKS 1312
+K + + P G + G PP PP P
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGA------PGLPGPPGPAGPHIPPSDEICEPGPP 456
Query: 1313 VPPSVPA-RGLQ------------------------PQPPATPAVPHPPPSGAF----GL 1343
PP P +GLQ P P P +P PP S F G
Sbjct: 457 GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGE 516
Query: 1344 GGALEAAESEGL-GL-GCP-SPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
G A +GL G+ G P +P + ++ T P D+ + + +
Sbjct: 517 KGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPG 576
Query: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP-- 1458
P L GPK P G PG P LPGLP + G PP P
Sbjct: 577 TPGQDGLPGLPGPK--GEPGGITFKGERGPPGNPGLPGLPG--NIGPMGPPGFGPPGPVG 632
Query: 1459 ----------PTPPPAPTPQPQPPPP-PPPPQPALPSPP--------PLVAPTPSSPPPP 1499
P P P P+ P P +P LP P P P P P
Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692
Query: 1500 PLP----PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
+P P P + P PP P + PP P P E P P
Sbjct: 693 GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742
Score = 48.1 bits (113), Expect = 9e-05
Identities = 44/144 (30%), Positives = 50/144 (34%), Gaps = 19/144 (13%)
Query: 1408 PPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLPS----ANSNGTPEPPLLEEKPPPTPP 1462
P L GPK P GPP P +PGP PGLP G P P L P
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1304
Query: 1463 PAPTPQPQPPPPPP--------PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514
P P Q P P P P +P P + P+ P P P PP
Sbjct: 1305 QGP-PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1363
Query: 1515 PPPPAAAPL-----AAPPEEPAAP 1533
P P+ + A PP P P
Sbjct: 1364 LPGPSGQSIIIKGDAGPPGIPGQP 1387
Score = 43.9 bits (102), Expect = 0.002
Identities = 76/297 (25%), Positives = 90/297 (30%), Gaps = 77/297 (25%)
Query: 1304 TPPLSPPKSV--PPSVPARGLQPQPPAT---PAVPHPPPS----GAFGLGG-ALEAAESE 1353
TP PK + PP P +P P P P PP G G+ G A + E
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185
Query: 1354 GLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP 1413
G G P P LP S + D + +P G
Sbjct: 1186 QPGFGNPGP------------PGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGF 1230
Query: 1414 KDTSTPDGPPLAPAAAV------PGPPPLPGLPSANSNGTPEPP--------LLEEKPPP 1459
P GPP +P A+ PGP PG P PE P + EK P
Sbjct: 1231 PGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNP 1290
Query: 1460 TPPPAP----------TPQPQPPPPPP--------PPQPALPSPPPLVAPT--PSSPPPP 1499
P P P Q P P P P +P P + P+ P S P
Sbjct: 1291 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1350
Query: 1500 PLP----PPPPPAMPSP------------PP--PPPPAAAPLAAPPEEPAAPSPEDP 1538
P PP PP +P P PP P P L P P P P
Sbjct: 1351 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1407
Score = 42.4 bits (98), Expect = 0.005
Identities = 43/148 (29%), Positives = 50/148 (33%), Gaps = 27/148 (18%)
Query: 1421 GPPLAPAAAVPGPPPLPGLPSANSNG-------TPEPPLLEEKP----------PPTPPP 1463
G P P PGPP LPGL +G P P + +P PP PP
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241
Query: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPP--------LPPPPPPAMPSPPPP 1515
+P P + P P PQ P P P PP P P P +P P
Sbjct: 1242 SPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301
Query: 1516 PPPAAAP-LAAPPEEPAAPSPE-DPELP 1541
P L P P + DP LP
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLP 1329
Score = 36.6 bits (83), Expect = 0.26
Identities = 72/291 (24%), Positives = 92/291 (31%), Gaps = 53/291 (18%)
Query: 73 DTGLH-HAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELF 131
+ G H G GP + ALE PGP P +Q GP L
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP-----GRPGFQGLPGPEGPPGLP 1278
Query: 132 ISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHL 191
+G + G P L P G + P LQ P P NG+
Sbjct: 1279 GNGGIKGEKGNPGQPGLPGL--PGLKGDQGPP-----GLQGNPGRPGLNGMKGD------ 1325
Query: 192 KPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASS 251
P +P GF G+ GP+G+ + P PG PP PP LP S
Sbjct: 1326 -----PGLPGVPGFP-----GMKGPSGVPGSAGPEGEPGLIGPPGPP-GLPG-----PSG 1369
Query: 252 SAAAAAAEQSSPQLYNFSG--AAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHA 309
+ + P + G PGP P+ LP PP P +
Sbjct: 1370 QSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ-GLP-------------GPTGPPGDPGRNG 1415
Query: 310 LQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASG 360
L + GG G L G P P G GP G ++ A G
Sbjct: 1416 LPGFDGAGGRKGDPGLPGQPGTRGL-DGPPGPD-GLQGPPGPPGTSSVAHG 1464
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 120 bits (302), Expect = 1e-26
Identities = 230/898 (25%), Positives = 281/898 (31%), Gaps = 204/898 (22%)
Query: 199 VPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAA 257
+P + G + L G G L +G Q PP PG P P P A +
Sbjct: 570 IPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP-----------AGPAGPPGY 618
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH-ALQHYLSC 316
Q P L G P PP A PR + + P P PP PP H Q
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS---TPVPGPPGPPGPPGHPGPQGPPGI 675
Query: 317 GGSYPSMGHRANLACSPLGGGEPS-PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG 375
GS G P GEP PG G P GP G
Sbjct: 676 PGSLGKCGDPG----LPGPDGEPGIPGIGFPGPPGPKGDQ-------------------- 711
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGA 435
G G + + PG K G+ G +P P + P GGP G+ G
Sbjct: 712 GFPGTKGSLGCPG-KMGEPGLPG------KPGLPGAKGEPAVAMPGGPGTPGFPGER-GN 763
Query: 436 GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQ 495
G G+ PG P G G + P G P PP PPG
Sbjct: 764 SGEHGEIGLPGLP-----------GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812
Query: 496 SYSPDQLQGQ--LYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
L G L G QG G+P S SP + GH G GP
Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872
Query: 554 GGG-------GEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G G +I + P A G P G+PG PG+ S + PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI--------PGVK 924
Query: 607 SYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG 666
G +GD PG P+E I H++ P G G GE G
Sbjct: 925 GQRGTPGAKGEQGDKGN----PG--PSE--------ISHVIGDKGEPGLKGFAGNPGEKG 970
Query: 667 -----AADASKGLGGSGGAGGPPGTPYELAKE-DPQRYHLQSVIRTSASLDEGATAALEL 720
KGL G G GPPG +L +P L+ + + ++ +
Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAK-ELGAFLQKSPPPPPPTAQSTQPTPH 779
LG P R G GL +H G K E G P PP PT P
Sbjct: 1031 TLGF-------PGRAGRP--GLPG--IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079
Query: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
G E G P PP L PA +GAP P P
Sbjct: 1080 GKKGEMGQPG-------PPGH-----------------------LGPAGPEGAPGSPGSP 1109
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P P P L G++ P +R PPG L P +PG G+
Sbjct: 1110 GLPGKPGP---HGDLGFKGIKGLLGPPGIR-----GPPG--------LPGFPGSPGPMGI 1153
Query: 900 ----------GPPNSEG-----KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
GP +G + P G +P QG K R P
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP---------------- 1197
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
FP + GA D G GP EG P PPG P G PG+ GP
Sbjct: 1198 -GFPGLPGR--KGAMGDAGPRGPTGIEGFP-----GPPGLP-----GAIIPGQTGNRGP- 1243
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
PG P P P + +G+ G + P P PP A P G L +P
Sbjct: 1244 -PGSRGSPGAPGP-PGPPGSHVIGI--KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Score = 101 bits (251), Expect = 9e-21
Identities = 235/906 (25%), Positives = 294/906 (32%), Gaps = 187/906 (20%)
Query: 173 PPFSPPANGLLSPHDVLHLK-PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP 231
PP SP G P + + P P +P G + GV G +GL P PG
Sbjct: 56 PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGFSGSPGLPGT 110
Query: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291
P P + L+ + + EQ P L G PG P ++ K
Sbjct: 111 PGNTGP-------YGLVGVPGCSGSKGEQGFPGLPGTLGY-PGIPGAAGLKGQKGAPAKE 162
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351
A+ P P A Q G +P P+G P G P GP
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPG-FPG----------PVGPPGPPGFFGFPGAMGP 211
Query: 352 SGATAGASGRATGPEAAGG----GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP 407
G R G + G G G G + P +T G G P
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271
Query: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQ 467
PP + P +S G A G G G PG +G+ G +GF G +
Sbjct: 272 PPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGS-EGVKG----NRGFPGLMGE 325
Query: 468 DLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA 527
D K GPP GP + Y Q +G G G P P A QG P+
Sbjct: 326 DGIKGQKGDIGPPGF-RGPT-------EYYDTYQEKGD-EGTPGPPGPRGARGPQG-PSG 375
Query: 528 SPSLSYSTGHS-PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG-VGSPGA 585
P + S G S P L G GW P G GE RP + T PG GSPG
Sbjct: 376 PPGVPGSPGSSRPGLRG-APGW-PGLKGSKGERG-----RPGKDAMGTPGSPGCAGSPGL 428
Query: 586 PGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPPAERTEDEEFLI 643
PG P PPG + G G G GS + G GP E L
Sbjct: 429 PGS------PGPP--GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE----PGLLC 476
Query: 644 QHLLQAPSPPRTSGADGL------VGEDGAADASKGLGGSGGAGGPPGTP-YELAKEDPQ 696
P PP G GL G GAA KG GS G G PG P + A+ DP
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA-GLKGSPGSPGNTGLPGFPGFPGAQGDP- 534
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
++G T E +G + + G + +G+ + G K L
Sbjct: 535 ----------GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT-----PGVKGL 579
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP--PP---PQLLPSV-----L 806
P P A S + G + G P P P PP PQ P + +
Sbjct: 580 -------PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632
Query: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
AP P A G E + P PP PP PP P P
Sbjct: 633 PGAPGPPGEAGPRG----ELSVSTPVPGPPGPPGPPGHPGP------------------- 669
Query: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PPG + G+L GD G+ P+ E P + P P G K +
Sbjct: 670 -------QGPPG----IPGSLGKC----GDPGLPGPDGEPGIPGIGF--PGPPGPKGDQG 712
Query: 927 VPLT--SICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
P T S+ P + G GK G P +G+P PG
Sbjct: 713 FPGTKGSLGCPGKM------------------GEPGLPGKPGLPGAKGEPAVAMPGGPGT 754
Query: 985 PAYDPYGPYCPGRASGAGPE----TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
P + PG +G PGL P LP T E L + P Q PP
Sbjct: 755 PGF-------PGERGNSGEHGEIGLPGL-------PGLPGTPGNEGLDGPRGDPGQPGPP 800
Query: 1041 PPPPPP 1046
PP
Sbjct: 801 GEQGPP 806
Score = 95.1 bits (235), Expect = 6e-19
Identities = 221/884 (25%), Positives = 275/884 (31%), Gaps = 211/884 (23%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPP 232
P SP + G P P P + + G G G GP G TP PGPP
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--PGPP 658
Query: 233 DPPPPPRH--------LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP------ 278
PP PP H +P E P + PGPP P
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-----GFPGPPGPKGDQGF 713
Query: 279 --------------ERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324
E LP + + PA A P P P G + G
Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFP--------GERGNSG 765
Query: 325 HRANLACSPLGGGEPSPG-------AGEPSKAGPSGATAGASGRATGPEAAGG------- 370
+ L G +PG G+P + GP G GP A G
Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGL 825
Query: 371 -------GGAGGGG---------GGYRPIIQSPGY--------KTGKGGYGAAAG----- 401
G G G G+ SPG G+ GY G
Sbjct: 826 KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPP 885
Query: 402 ------------GATRPP-PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
GA PP PP + TP + G GA G G +PG
Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPS 945
Query: 449 Q--GLLGPQAYG--QGFGGGQAQDLSKA----PSYSGGPPQP-PSGPPPPGLATCQSYSP 499
+ ++G + +GF G + ++ P G P P+GPP P + +P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNP 1005
Query: 500 DQ-----LQGQLYGVQGEP----------YPGPAAHS-----QGLPTASPSLSYSTGHSP 539
+ + G + G G P +PG A GL YS G P
Sbjct: 1006 GEPGLRGIPGSM-GNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Query: 540 ALSGHGGGWG-PSSLGGGGE----ASPSHIIRPLQSPPATGRPPGVGSPGAPG------- 587
G G G P +G GE P H + P A G P G PG PG
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGPPGH-LGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123
Query: 588 KYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD-GSELLAGPGGPPAERTEDEEFLIQHL 646
K + +L PPG + G +GD G + + GP G E L
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE---------TGL 1174
Query: 647 LQAPSPPR-TSGADGLVGEDGA-----ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHL 700
L+AP PR GA G G+ GA KG G G GP G + P L
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG-----IEGFPGPPGL 1229
Query: 701 QSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFL 760
I + + G + + P G P G S V G K G+
Sbjct: 1230 PGAIIPGQTGNRGPPGS-----------RGSP--GAPGPPGPPGSHVIGIKGDK--GSMG 1274
Query: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
P PP TA P G L G P LP P Q P V +P
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL----- 1327
Query: 821 VHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAM 880
G+ PP P P PP L+ L P +P P P E PG
Sbjct: 1328 ----------GSIGPPGPIGPKGPPGVRGDPGTLKIISL-PGSPGPPGTPGE----PGMQ 1372
Query: 881 QELLGALEPLPPA-PGDTG-VGPPNSEGKDPAGAYRSPSPQGTK 922
EP PP PG+ G GP GKD G +P P G K
Sbjct: 1373 G------EPGPPGPPGNLGPCGPRGKPGKD--GKPGTPGPAGEK 1408
Score = 74.7 bits (182), Expect = 9e-13
Identities = 165/635 (25%), Positives = 202/635 (31%), Gaps = 136/635 (21%)
Query: 124 TPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPPFSPPANGL 182
TPG T + +PG S S G + FP +P +L P P A GL
Sbjct: 110 TPGNTGPYGLVGVPGCS--------------GSKGEQGFPGLPGTLGY---PGIPGAAGL 152
Query: 183 LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLP 242
AP + + G+ G G PP PGP PP PP
Sbjct: 153 KGQKG--------APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG--- 201
Query: 243 TQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPPPERAL------PRQDTVIKH 291
F + ++ G GPP P + P T +K
Sbjct: 202 --FFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAG 350
+ A P PP L G SY S G PG G+P K G
Sbjct: 260 EKGDKGAMGEPGPPGPSGLP-----GESYGSEK-----------GAPGDPGLQGKPGKDG 303
Query: 351 PSG--ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGA----AAGGAT 404
G + G G P G G G G P PG++ Y G
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP----PGFRGPTEYYDTYQEKGDEGTP 359
Query: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGG 464
PP PR P Q GP + +S G G +PG P GL G + +G G
Sbjct: 360 GPPGPRGARGP--QGPSGPPGVPGSPGSSRPGLRG----APGWP-GLKGSKGE-RGRPGK 411
Query: 465 QAQDLSKAPSYSGGPPQPPS-GPP-PPGLATCQSYSPDQ--LQGQLY--------GVQGE 512
A +P +G P P S GPP PPG + P L G L G +GE
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 513 P---------------YPG-PAAHS-QGLP--------TASPSLSYSTGHSPALSGHGGG 547
P PG P H +G+P SP +TG P G G
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG-LPGFPGFPGA 530
Query: 548 WGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
G L G G P + P G+P G G PG + + P P G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPG---TPGVKGLP--GPKGE 585
Query: 606 GSYAAGAGGYKGKGD----GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
+ + G GD GS AGP GPP + E P T G G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE----------PGLQGTQGVPGA 635
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQ 696
G G A L S GPPG P PQ
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670
Score = 57.8 bits (138), Expect = 1e-07
Identities = 179/734 (24%), Positives = 227/734 (30%), Gaps = 126/734 (17%)
Query: 890 LPPAPGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945
LP PG+TG VG P G G P GT +P + L+ ++ +
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSK--GEQGFPGLPGTLGYPGIPGAAG------LKGQKGA 158
Query: 946 FFPTMEEMFGGGAADDYGKAGPPEDEG--DPKAGAGP--PPGPPAY-------DPYGP-- 992
P EE A D G G P +G P GP PPGPP + P GP
Sbjct: 159 --PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216
Query: 993 YCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI-------QSGPHQAAPPPPPPP 1045
+ R G E GL PP P TV G + G A P PP
Sbjct: 217 HMGERVIGHKGERGVKGL--TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 1046 PPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADE 1105
P GL + S K DP Q
Sbjct: 275 P----------SGLPGESYGSEKGAP------------GDPGLQ-------------GKP 299
Query: 1106 DKADVPA-----DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPT 1160
K VP ++ N R P L+ + +G F P D + +G + T
Sbjct: 300 GKDGVPGFPGSEGVKGN-RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358
Query: 1161 KAKRDGPPRPRG-RPRIRPLEVPTTAGPASASTP----TDGAKKPRGRGRGRGRKAEEAG 1215
GPP PRG R P P G +S P G +G RGR ++A
Sbjct: 359 P----GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414
Query: 1216 GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
GT P P G GD + D L I V+ P
Sbjct: 415 GT---PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG-DHGLPGYLGSPGIPGVDG--P 468
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP--PATPAVP 1333
+ + G + + ++ P L P L K +P A GL+ P P +P
Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGL------PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522
Query: 1334 ----HPPPSGAFGLGGAL-EAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
P G GL G E + EG +G P + ++ L+ +P +
Sbjct: 523 GFPGFPGAQGDPGLKGEKGETLQPEGQ-VGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLPGLPSANSN 1445
K DP G + P GPP PG +PG P
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641
Query: 1446 GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 1505
P L P P PP P P P P PP P P P P P P
Sbjct: 642 AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGK----CGDPGLPGPDGEPGIP 697
Query: 1506 PPAMPSPPPPP-----PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCG- 1559
P PP P P L P + P P LP AK + A+ G
Sbjct: 698 GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG------AKGEPAVAMPGG 751
Query: 1560 -ETDEEAGESGGEG 1572
T GE G G
Sbjct: 752 PGTPGFPGERGNSG 765
Score = 53.9 bits (128), Expect = 2e-06
Identities = 231/941 (24%), Positives = 276/941 (29%), Gaps = 230/941 (24%)
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRT-SGADGLVGEDG 666
+ GA G KG+ GP G P ++ F L P P+ G GL G G
Sbjct: 40 FCDGAKGEKGEKG----FPGPPGSPGQKG----FTGPEGLPGPQGPKGFPGLPGLTGSKG 91
Query: 667 AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK 726
S GL G G+ G PGTP Y L V S S E L LG
Sbjct: 92 VRGIS-GLPGFSGSPGLPGTPGNTGP-----YGLVGVPGCSGSKGEQGFPGLPGTLGY-- 143
Query: 727 EKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
G A GA AKE L P P A P P GL G
Sbjct: 144 ----------PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA----PGPQGL---PG 186
Query: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK--VGVHLLEPATRDGAPQPPPPPPPPPP 844
P P + PP P P + P K +G ++ G PP PP
Sbjct: 187 PPGFPGPVGPPGP---PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243
Query: 845 PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
+ + P R + GAM E P PG +G+ P S
Sbjct: 244 VI------------VTLTGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGL-PGES 282
Query: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964
G + GA P QG VP FP S R F M E G G
Sbjct: 283 YGSEK-GAPGDPGLQGKPGKDGVP----GFPGSEGVKGNRGFPGLMGE---DGIKGQKGD 334
Query: 965 AGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE-TPGLGLDPNKPPELPSTVN 1023
GPP G + YD Y G E TPG PP
Sbjct: 335 IGPPGFRGPTEY----------YDTY--------QEKGDEGTPG-------PP------- 362
Query: 1024 AEPLGLIQSGPHQAAPPPPPPPPP--PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLL 1081
GP A P P PP P +P S G +P + K K
Sbjct: 363 ---------GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK---------- 403
Query: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPAL------- 1134
R P +D P C P L
Sbjct: 404 GERGRP----------------GKDAMGTPGS------------PGCAGSPGLPGSPGPP 435
Query: 1135 SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASAS--T 1192
P GDI F PG G P DGP +G P + + P GP
Sbjct: 436 GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---KGEPGLLCTQCPYIPGPPGLPGLP 492
Query: 1193 PTDGAKKPRGRGRGRGRKAEEAG-------------GTRLEP-LKPLKIKLSVPKAGEGL 1238
G K GR G K G + +P LK K + P+ G+
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552
Query: 1239 GTSSG----------DAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDF 1288
G D I GT L K E + EK + G S
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVK---GLPGPKGELALSG--EKGDQGPPGDPGSPGSP 607
Query: 1289 LKSGKRHPPLYQAGLTPPLSPPKSVP--PSVPARGLQ----------PQPPATPAVP-HP 1335
+G PP Y P L + VP P P P PP P P HP
Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667
Query: 1336 PPSGAFGLGGALEAAESEGL----------GLGCPSPC-KRLDEELKRNLETLPSFSSDE 1384
P G G+ G+L GL G+G P P + D+ +L
Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727
Query: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
E + L A +P +A P TP P + G LPGLP
Sbjct: 728 EPGLPGKPGLP-------GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP---- 776
Query: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
G P P E P P QP PP PP + P
Sbjct: 777 -GLPGTPGNEGLDGPRGDPG---QPGPPGEQGPPGRCIEGP 813
Score = 47.0 bits (110), Expect = 2e-04
Identities = 57/217 (26%), Positives = 70/217 (32%), Gaps = 45/217 (20%)
Query: 1404 ALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP-SANSNGTPEPP---------LL 1453
A+ D GP GPP P A +PG G P S S G P PP +
Sbjct: 1208 AMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 1454 EEK-----PPPTPPPAPTPQPQPPPP-PPPPQPALPSPP--------PLVAPTPSSP--- 1496
+K P P PP PP P P LP P P V +P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL 1327
Query: 1497 ----PPPPLPPPPPPAM-------------PSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
PP P+ P PP + SP PP P + P P P P
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387
Query: 1540 LPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRE 1576
P +P K T GE + + E +F +
Sbjct: 1388 GPRGKP-GKDGKPGTPGPAGEKGNKGSKGEPESLFHQ 1423
Score = 39.7 bits (91), Expect = 0.030
Identities = 63/251 (25%), Positives = 75/251 (29%), Gaps = 49/251 (19%)
Query: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
PP + P+ P P P +P +P P P G G G +GL LG P
Sbjct: 1090 PPGHLGPAGPEGA--PGSPGSPGLPGKPGPHGDLGFKGI------KGL-LGPPGI----- 1135
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL--AGPKDTSTPDGPPLA 1425
R LP F + ++ I + L A P P
Sbjct: 1136 ----RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
PG P LPG A + P PT P PP P +P
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPR--------------GPTGIEGFPGPPGLPGAIIPGQ 1237
Query: 1486 PPLVAPTPSSPPPPPLPPPPPP------------AMPSPPPPPPPAAAPLAAPPEEPAAP 1533
P S P PP PP +M P P PP A PP AP
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Query: 1534 SPEDPELPDTR 1544
P LP R
Sbjct: 1298 G--TPGLPGPR 1306
Score = 32.3 bits (72), Expect = 4.9
Identities = 33/115 (28%), Positives = 38/115 (33%), Gaps = 24/115 (20%)
Query: 1431 PGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPAPTPQPQPPPP---------PPPPQP 1480
PG PGLP + G P E P PP PT P P P PP
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGH 1093
Query: 1481 ALPSPPPLVAPTPSSPPPPPLPPP-------------PPPAMPSPPPPPPPAAAP 1522
P+ P +P SP P P P PP + PP P +P
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148
Score = 31.6 bits (70), Expect = 8.3
Identities = 41/153 (26%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 1697 PAPPPKPET--PEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPL 1754
P PP P P +T + PP P PP P ++ + +K + G
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI-----GIKGDKGSMGHPGP 1278
Query: 1755 RGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK----WLKEAGGNAT 1810
+G T+G P R G P T LP R P K +K +L G
Sbjct: 1279 KGPPGTAGDMGPPGR---LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335
Query: 1811 AG-GGPPGSSSD-----------SESSPGAPSE 1831
G GPPG D S PG P E
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 120 bits (302), Expect = 1e-26
Identities = 230/898 (25%), Positives = 281/898 (31%), Gaps = 204/898 (22%)
Query: 199 VPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAA 257
+P + G + L G G L +G Q PP PG P P P A +
Sbjct: 570 IPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP-----------AGPAGPPGY 618
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH-ALQHYLSC 316
Q P L G P PP A PR + + P P PP PP H Q
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS---TPVPGPPGPPGPPGHPGPQGPPGI 675
Query: 317 GGSYPSMGHRANLACSPLGGGEPS-PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG 375
GS G P GEP PG G P GP G
Sbjct: 676 PGSLGKCGDPG----LPGPDGEPGIPGIGFPGPPGPKGDQ-------------------- 711
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGA 435
G G + + PG K G+ G +P P + P GGP G+ G
Sbjct: 712 GFPGTKGSLGCPG-KMGEPGLPG------KPGLPGAKGEPAVAMPGGPGTPGFPGER-GN 763
Query: 436 GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQ 495
G G+ PG P G G + P G P PP PPG
Sbjct: 764 SGEHGEIGLPGLP-----------GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812
Query: 496 SYSPDQLQGQ--LYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
L G L G QG G+P S SP + GH G GP
Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872
Query: 554 GGG-------GEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G G +I + P A G P G+PG PG+ S + PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI--------PGVK 924
Query: 607 SYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG 666
G +GD PG P+E I H++ P G G GE G
Sbjct: 925 GQRGTPGAKGEQGDKGN----PG--PSE--------ISHVIGDKGEPGLKGFAGNPGEKG 970
Query: 667 -----AADASKGLGGSGGAGGPPGTPYELAKE-DPQRYHLQSVIRTSASLDEGATAALEL 720
KGL G G GPPG +L +P L+ + + ++ +
Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAK-ELGAFLQKSPPPPPPTAQSTQPTPH 779
LG P R G GL +H G K E G P PP PT P
Sbjct: 1031 TLGF-------PGRAGRP--GLPG--IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079
Query: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
G E G P PP L PA +GAP P P
Sbjct: 1080 GKKGEMGQPG-------PPGH-----------------------LGPAGPEGAPGSPGSP 1109
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P P P L G++ P +R PPG L P +PG G+
Sbjct: 1110 GLPGKPGP---HGDLGFKGIKGLLGPPGIR-----GPPG--------LPGFPGSPGPMGI 1153
Query: 900 ----------GPPNSEG-----KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
GP +G + P G +P QG K R P
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP---------------- 1197
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
FP + GA D G GP EG P PPG P G PG+ GP
Sbjct: 1198 -GFPGLPGR--KGAMGDAGPRGPTGIEGFP-----GPPGLP-----GAIIPGQTGNRGP- 1243
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
PG P P P + +G+ G + P P PP A P G L +P
Sbjct: 1244 -PGSRGSPGAPGP-PGPPGSHVIGI--KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Score = 101 bits (251), Expect = 9e-21
Identities = 235/906 (25%), Positives = 294/906 (32%), Gaps = 187/906 (20%)
Query: 173 PPFSPPANGLLSPHDVLHLK-PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP 231
PP SP G P + + P P +P G + GV G +GL P PG
Sbjct: 56 PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGFSGSPGLPGT 110
Query: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291
P P + L+ + + EQ P L G PG P ++ K
Sbjct: 111 PGNTGP-------YGLVGVPGCSGSKGEQGFPGLPGTLGY-PGIPGAAGLKGQKGAPAKE 162
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351
A+ P P A Q G +P P+G P G P GP
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPG-FPG----------PVGPPGPPGFFGFPGAMGP 211
Query: 352 SGATAGASGRATGPEAAGG----GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP 407
G R G + G G G G + P +T G G P
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271
Query: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQ 467
PP + P +S G A G G G PG +G+ G +GF G +
Sbjct: 272 PPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGS-EGVKG----NRGFPGLMGE 325
Query: 468 DLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA 527
D K GPP GP + Y Q +G G G P P A QG P+
Sbjct: 326 DGIKGQKGDIGPPGF-RGPT-------EYYDTYQEKGD-EGTPGPPGPRGARGPQG-PSG 375
Query: 528 SPSLSYSTGHS-PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG-VGSPGA 585
P + S G S P L G GW P G GE RP + T PG GSPG
Sbjct: 376 PPGVPGSPGSSRPGLRG-APGW-PGLKGSKGERG-----RPGKDAMGTPGSPGCAGSPGL 428
Query: 586 PGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPPAERTEDEEFLI 643
PG P PPG + G G G GS + G GP E L
Sbjct: 429 PGS------PGPP--GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE----PGLLC 476
Query: 644 QHLLQAPSPPRTSGADGL------VGEDGAADASKGLGGSGGAGGPPGTP-YELAKEDPQ 696
P PP G GL G GAA KG GS G G PG P + A+ DP
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA-GLKGSPGSPGNTGLPGFPGFPGAQGDP- 534
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
++G T E +G + + G + +G+ + G K L
Sbjct: 535 ----------GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT-----PGVKGL 579
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP--PP---PQLLPSV-----L 806
P P A S + G + G P P P PP PQ P + +
Sbjct: 580 -------PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632
Query: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
AP P A G E + P PP PP PP P P
Sbjct: 633 PGAPGPPGEAGPRG----ELSVSTPVPGPPGPPGPPGHPGP------------------- 669
Query: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PPG + G+L GD G+ P+ E P + P P G K +
Sbjct: 670 -------QGPPG----IPGSLGKC----GDPGLPGPDGEPGIPGIGF--PGPPGPKGDQG 712
Query: 927 VPLT--SICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
P T S+ P + G GK G P +G+P PG
Sbjct: 713 FPGTKGSLGCPGKM------------------GEPGLPGKPGLPGAKGEPAVAMPGGPGT 754
Query: 985 PAYDPYGPYCPGRASGAGPE----TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
P + PG +G PGL P LP T E L + P Q PP
Sbjct: 755 PGF-------PGERGNSGEHGEIGLPGL-------PGLPGTPGNEGLDGPRGDPGQPGPP 800
Query: 1041 PPPPPP 1046
PP
Sbjct: 801 GEQGPP 806
Score = 95.1 bits (235), Expect = 6e-19
Identities = 221/884 (25%), Positives = 275/884 (31%), Gaps = 211/884 (23%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPP 232
P SP + G P P P + + G G G GP G TP PGPP
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--PGPP 658
Query: 233 DPPPPPRH--------LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP------ 278
PP PP H +P E P + PGPP P
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-----GFPGPPGPKGDQGF 713
Query: 279 --------------ERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324
E LP + + PA A P P P G + G
Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFP--------GERGNSG 765
Query: 325 HRANLACSPLGGGEPSPG-------AGEPSKAGPSGATAGASGRATGPEAAGG------- 370
+ L G +PG G+P + GP G GP A G
Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGL 825
Query: 371 -------GGAGGGG---------GGYRPIIQSPGY--------KTGKGGYGAAAG----- 401
G G G G+ SPG G+ GY G
Sbjct: 826 KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPP 885
Query: 402 ------------GATRPP-PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
GA PP PP + TP + G GA G G +PG
Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPS 945
Query: 449 Q--GLLGPQAYG--QGFGGGQAQDLSKA----PSYSGGPPQP-PSGPPPPGLATCQSYSP 499
+ ++G + +GF G + ++ P G P P+GPP P + +P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNP 1005
Query: 500 DQ-----LQGQLYGVQGEP----------YPGPAAHS-----QGLPTASPSLSYSTGHSP 539
+ + G + G G P +PG A GL YS G P
Sbjct: 1006 GEPGLRGIPGSM-GNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Query: 540 ALSGHGGGWG-PSSLGGGGE----ASPSHIIRPLQSPPATGRPPGVGSPGAPG------- 587
G G G P +G GE P H + P A G P G PG PG
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGPPGH-LGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123
Query: 588 KYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD-GSELLAGPGGPPAERTEDEEFLIQHL 646
K + +L PPG + G +GD G + + GP G E L
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE---------TGL 1174
Query: 647 LQAPSPPR-TSGADGLVGEDGA-----ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHL 700
L+AP PR GA G G+ GA KG G G GP G + P L
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG-----IEGFPGPPGL 1229
Query: 701 QSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFL 760
I + + G + + P G P G S V G K G+
Sbjct: 1230 PGAIIPGQTGNRGPPGS-----------RGSP--GAPGPPGPPGSHVIGIKGDK--GSMG 1274
Query: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
P PP TA P G L G P LP P Q P V +P
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL----- 1327
Query: 821 VHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAM 880
G+ PP P P PP L+ L P +P P P E PG
Sbjct: 1328 ----------GSIGPPGPIGPKGPPGVRGDPGTLKIISL-PGSPGPPGTPGE----PGMQ 1372
Query: 881 QELLGALEPLPPA-PGDTG-VGPPNSEGKDPAGAYRSPSPQGTK 922
EP PP PG+ G GP GKD G +P P G K
Sbjct: 1373 G------EPGPPGPPGNLGPCGPRGKPGKD--GKPGTPGPAGEK 1408
Score = 74.7 bits (182), Expect = 9e-13
Identities = 165/635 (25%), Positives = 202/635 (31%), Gaps = 136/635 (21%)
Query: 124 TPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPPFSPPANGL 182
TPG T + +PG S S G + FP +P +L P P A GL
Sbjct: 110 TPGNTGPYGLVGVPGCS--------------GSKGEQGFPGLPGTLGY---PGIPGAAGL 152
Query: 183 LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLP 242
AP + + G+ G G PP PGP PP PP
Sbjct: 153 KGQKG--------APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG--- 201
Query: 243 TQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPPPERAL------PRQDTVIKH 291
F + ++ G GPP P + P T +K
Sbjct: 202 --FFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAG 350
+ A P PP L G SY S G PG G+P K G
Sbjct: 260 EKGDKGAMGEPGPPGPSGLP-----GESYGSEK-----------GAPGDPGLQGKPGKDG 303
Query: 351 PSG--ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGA----AAGGAT 404
G + G G P G G G G P PG++ Y G
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP----PGFRGPTEYYDTYQEKGDEGTP 359
Query: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGG 464
PP PR P Q GP + +S G G +PG P GL G + +G G
Sbjct: 360 GPPGPRGARGP--QGPSGPPGVPGSPGSSRPGLRG----APGWP-GLKGSKGE-RGRPGK 411
Query: 465 QAQDLSKAPSYSGGPPQPPS-GPP-PPGLATCQSYSPDQ--LQGQLY--------GVQGE 512
A +P +G P P S GPP PPG + P L G L G +GE
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 513 P---------------YPG-PAAHS-QGLP--------TASPSLSYSTGHSPALSGHGGG 547
P PG P H +G+P SP +TG P G G
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG-LPGFPGFPGA 530
Query: 548 WGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
G L G G P + P G+P G G PG + + P P G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPG---TPGVKGLP--GPKGE 585
Query: 606 GSYAAGAGGYKGKGD----GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
+ + G GD GS AGP GPP + E P T G G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE----------PGLQGTQGVPGA 635
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQ 696
G G A L S GPPG P PQ
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670
Score = 57.8 bits (138), Expect = 1e-07
Identities = 179/734 (24%), Positives = 227/734 (30%), Gaps = 126/734 (17%)
Query: 890 LPPAPGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945
LP PG+TG VG P G G P GT +P + L+ ++ +
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSK--GEQGFPGLPGTLGYPGIPGAAG------LKGQKGA 158
Query: 946 FFPTMEEMFGGGAADDYGKAGPPEDEG--DPKAGAGP--PPGPPAY-------DPYGP-- 992
P EE A D G G P +G P GP PPGPP + P GP
Sbjct: 159 --PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216
Query: 993 YCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI-------QSGPHQAAPPPPPPP 1045
+ R G E GL PP P TV G + G A P PP
Sbjct: 217 HMGERVIGHKGERGVKGL--TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 1046 PPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADE 1105
P GL + S K DP Q
Sbjct: 275 P----------SGLPGESYGSEKGAP------------GDPGLQ-------------GKP 299
Query: 1106 DKADVPA-----DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPT 1160
K VP ++ N R P L+ + +G F P D + +G + T
Sbjct: 300 GKDGVPGFPGSEGVKGN-RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358
Query: 1161 KAKRDGPPRPRG-RPRIRPLEVPTTAGPASASTP----TDGAKKPRGRGRGRGRKAEEAG 1215
GPP PRG R P P G +S P G +G RGR ++A
Sbjct: 359 P----GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414
Query: 1216 GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
GT P P G GD + D L I V+ P
Sbjct: 415 GT---PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG-DHGLPGYLGSPGIPGVDG--P 468
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP--PATPAVP 1333
+ + G + + ++ P L P L K +P A GL+ P P +P
Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGL------PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522
Query: 1334 ----HPPPSGAFGLGGAL-EAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
P G GL G E + EG +G P + ++ L+ +P +
Sbjct: 523 GFPGFPGAQGDPGLKGEKGETLQPEGQ-VGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLPGLPSANSN 1445
K DP G + P GPP PG +PG P
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641
Query: 1446 GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 1505
P L P P PP P P P P PP P P P P P P
Sbjct: 642 AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGK----CGDPGLPGPDGEPGIP 697
Query: 1506 PPAMPSPPPPP-----PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCG- 1559
P PP P P L P + P P LP AK + A+ G
Sbjct: 698 GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG------AKGEPAVAMPGG 751
Query: 1560 -ETDEEAGESGGEG 1572
T GE G G
Sbjct: 752 PGTPGFPGERGNSG 765
Score = 53.9 bits (128), Expect = 2e-06
Identities = 231/941 (24%), Positives = 276/941 (29%), Gaps = 230/941 (24%)
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRT-SGADGLVGEDG 666
+ GA G KG+ GP G P ++ F L P P+ G GL G G
Sbjct: 40 FCDGAKGEKGEKG----FPGPPGSPGQKG----FTGPEGLPGPQGPKGFPGLPGLTGSKG 91
Query: 667 AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK 726
S GL G G+ G PGTP Y L V S S E L LG
Sbjct: 92 VRGIS-GLPGFSGSPGLPGTPGNTGP-----YGLVGVPGCSGSKGEQGFPGLPGTLGY-- 143
Query: 727 EKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
G A GA AKE L P P A P P GL G
Sbjct: 144 ----------PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA----PGPQGL---PG 186
Query: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK--VGVHLLEPATRDGAPQPPPPPPPPPP 844
P P + PP P P + P K +G ++ G PP PP
Sbjct: 187 PPGFPGPVGPPGP---PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243
Query: 845 PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
+ + P R + GAM E P PG +G+ P S
Sbjct: 244 VI------------VTLTGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGL-PGES 282
Query: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964
G + GA P QG VP FP S R F M E G G
Sbjct: 283 YGSEK-GAPGDPGLQGKPGKDGVP----GFPGSEGVKGNRGFPGLMGE---DGIKGQKGD 334
Query: 965 AGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE-TPGLGLDPNKPPELPSTVN 1023
GPP G + YD Y G E TPG PP
Sbjct: 335 IGPPGFRGPTEY----------YDTY--------QEKGDEGTPG-------PP------- 362
Query: 1024 AEPLGLIQSGPHQAAPPPPPPPPP--PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLL 1081
GP A P P PP P +P S G +P + K K
Sbjct: 363 ---------GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK---------- 403
Query: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPAL------- 1134
R P +D P C P L
Sbjct: 404 GERGRP----------------GKDAMGTPGS------------PGCAGSPGLPGSPGPP 435
Query: 1135 SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASAS--T 1192
P GDI F PG G P DGP +G P + + P GP
Sbjct: 436 GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---KGEPGLLCTQCPYIPGPPGLPGLP 492
Query: 1193 PTDGAKKPRGRGRGRGRKAEEAG-------------GTRLEP-LKPLKIKLSVPKAGEGL 1238
G K GR G K G + +P LK K + P+ G+
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552
Query: 1239 GTSSG----------DAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDF 1288
G D I GT L K E + EK + G S
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVK---GLPGPKGELALSG--EKGDQGPPGDPGSPGSP 607
Query: 1289 LKSGKRHPPLYQAGLTPPLSPPKSVP--PSVPARGLQ----------PQPPATPAVP-HP 1335
+G PP Y P L + VP P P P PP P P HP
Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667
Query: 1336 PPSGAFGLGGALEAAESEGL----------GLGCPSPC-KRLDEELKRNLETLPSFSSDE 1384
P G G+ G+L GL G+G P P + D+ +L
Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727
Query: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
E + L A +P +A P TP P + G LPGLP
Sbjct: 728 EPGLPGKPGLP-------GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP---- 776
Query: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
G P P E P P QP PP PP + P
Sbjct: 777 -GLPGTPGNEGLDGPRGDPG---QPGPPGEQGPPGRCIEGP 813
Score = 45.8 bits (107), Expect = 4e-04
Identities = 58/213 (27%), Positives = 68/213 (31%), Gaps = 52/213 (24%)
Query: 1404 ALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP-SANSNGTPEPP---------LL 1453
A+ D GP GPP P A +PG G P S S G P PP +
Sbjct: 1208 AMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 1454 EEK-----PPPTPPPAPTPQPQPPPP-PPPPQPALPSPP--------PLVAPTPSSP--- 1496
+K P P PP PP P P LP P P V +P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL 1327
Query: 1497 ----PPPPLPPPPPPAM-------------PSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
PP P+ P PP + SP PP P + P P P P
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387
Query: 1540 LPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
P +P K T AGE G +G
Sbjct: 1388 GPRGKPGKDGKP--------GTPGPAGEKGNKG 1412
Score = 39.7 bits (91), Expect = 0.030
Identities = 63/251 (25%), Positives = 75/251 (29%), Gaps = 49/251 (19%)
Query: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
PP + P+ P P P +P +P P P G G G +GL LG P
Sbjct: 1090 PPGHLGPAGPEGA--PGSPGSPGLPGKPGPHGDLGFKGI------KGL-LGPPGI----- 1135
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL--AGPKDTSTPDGPPLA 1425
R LP F + ++ I + L A P P
Sbjct: 1136 ----RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
PG P LPG A + P PT P PP P +P
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPR--------------GPTGIEGFPGPPGLPGAIIPGQ 1237
Query: 1486 PPLVAPTPSSPPPPPLPPPPPP------------AMPSPPPPPPPAAAPLAAPPEEPAAP 1533
P S P PP PP +M P P PP A PP AP
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Query: 1534 SPEDPELPDTR 1544
P LP R
Sbjct: 1298 G--TPGLPGPR 1306
Score = 32.3 bits (72), Expect = 4.9
Identities = 33/115 (28%), Positives = 38/115 (33%), Gaps = 24/115 (20%)
Query: 1431 PGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPAPTPQPQPPPP---------PPPPQP 1480
PG PGLP + G P E P PP PT P P P PP
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGH 1093
Query: 1481 ALPSPPPLVAPTPSSPPPPPLPPP-------------PPPAMPSPPPPPPPAAAP 1522
P+ P +P SP P P P PP + PP P +P
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148
Score = 31.6 bits (70), Expect = 8.3
Identities = 41/153 (26%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 1697 PAPPPKPET--PEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPL 1754
P PP P P +T + PP P PP P ++ + +K + G
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI-----GIKGDKGSMGHPGP 1278
Query: 1755 RGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK----WLKEAGGNAT 1810
+G T+G P R G P T LP R P K +K +L G
Sbjct: 1279 KGPPGTAGDMGPPGR---LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335
Query: 1811 AG-GGPPGSSSD-----------SESSPGAPSE 1831
G GPPG D S PG P E
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 120 bits (302), Expect = 1e-26
Identities = 230/898 (25%), Positives = 281/898 (31%), Gaps = 204/898 (22%)
Query: 199 VPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAA 257
+P + G + L G G L +G Q PP PG P P P A +
Sbjct: 570 IPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP-----------AGPAGPPGY 618
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH-ALQHYLSC 316
Q P L G P PP A PR + + P P PP PP H Q
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS---TPVPGPPGPPGPPGHPGPQGPPGI 675
Query: 317 GGSYPSMGHRANLACSPLGGGEPS-PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG 375
GS G P GEP PG G P GP G
Sbjct: 676 PGSLGKCGDPG----LPGPDGEPGIPGIGFPGPPGPKGDQ-------------------- 711
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGA 435
G G + + PG K G+ G +P P + P GGP G+ G
Sbjct: 712 GFPGTKGSLGCPG-KMGEPGLPG------KPGLPGAKGEPAVAMPGGPGTPGFPGER-GN 763
Query: 436 GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQ 495
G G+ PG P G G + P G P PP PPG
Sbjct: 764 SGEHGEIGLPGLP-----------GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812
Query: 496 SYSPDQLQGQ--LYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
L G L G QG G+P S SP + GH G GP
Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872
Query: 554 GGG-------GEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G G +I + P A G P G+PG PG+ S + PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI--------PGVK 924
Query: 607 SYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG 666
G +GD PG P+E I H++ P G G GE G
Sbjct: 925 GQRGTPGAKGEQGDKGN----PG--PSE--------ISHVIGDKGEPGLKGFAGNPGEKG 970
Query: 667 -----AADASKGLGGSGGAGGPPGTPYELAKE-DPQRYHLQSVIRTSASLDEGATAALEL 720
KGL G G GPPG +L +P L+ + + ++ +
Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAK-ELGAFLQKSPPPPPPTAQSTQPTPH 779
LG P R G GL +H G K E G P PP PT P
Sbjct: 1031 TLGF-------PGRAGRP--GLPG--IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079
Query: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
G E G P PP L PA +GAP P P
Sbjct: 1080 GKKGEMGQPG-------PPGH-----------------------LGPAGPEGAPGSPGSP 1109
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P P P L G++ P +R PPG L P +PG G+
Sbjct: 1110 GLPGKPGP---HGDLGFKGIKGLLGPPGIR-----GPPG--------LPGFPGSPGPMGI 1153
Query: 900 ----------GPPNSEG-----KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
GP +G + P G +P QG K R P
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP---------------- 1197
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
FP + GA D G GP EG P PPG P G PG+ GP
Sbjct: 1198 -GFPGLPGR--KGAMGDAGPRGPTGIEGFP-----GPPGLP-----GAIIPGQTGNRGP- 1243
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
PG P P P + +G+ G + P P PP A P G L +P
Sbjct: 1244 -PGSRGSPGAPGP-PGPPGSHVIGI--KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Score = 101 bits (251), Expect = 9e-21
Identities = 235/906 (25%), Positives = 294/906 (32%), Gaps = 187/906 (20%)
Query: 173 PPFSPPANGLLSPHDVLHLK-PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP 231
PP SP G P + + P P +P G + GV G +GL P PG
Sbjct: 56 PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGFSGSPGLPGT 110
Query: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291
P P + L+ + + EQ P L G PG P ++ K
Sbjct: 111 PGNTGP-------YGLVGVPGCSGSKGEQGFPGLPGTLGY-PGIPGAAGLKGQKGAPAKE 162
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351
A+ P P A Q G +P P+G P G P GP
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPG-FPG----------PVGPPGPPGFFGFPGAMGP 211
Query: 352 SGATAGASGRATGPEAAGG----GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP 407
G R G + G G G G + P +T G G P
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271
Query: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQ 467
PP + P +S G A G G G PG +G+ G +GF G +
Sbjct: 272 PPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGS-EGVKG----NRGFPGLMGE 325
Query: 468 DLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA 527
D K GPP GP + Y Q +G G G P P A QG P+
Sbjct: 326 DGIKGQKGDIGPPGF-RGPT-------EYYDTYQEKGD-EGTPGPPGPRGARGPQG-PSG 375
Query: 528 SPSLSYSTGHS-PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG-VGSPGA 585
P + S G S P L G GW P G GE RP + T PG GSPG
Sbjct: 376 PPGVPGSPGSSRPGLRG-APGW-PGLKGSKGERG-----RPGKDAMGTPGSPGCAGSPGL 428
Query: 586 PGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPPAERTEDEEFLI 643
PG P PPG + G G G GS + G GP E L
Sbjct: 429 PGS------PGPP--GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE----PGLLC 476
Query: 644 QHLLQAPSPPRTSGADGL------VGEDGAADASKGLGGSGGAGGPPGTP-YELAKEDPQ 696
P PP G GL G GAA KG GS G G PG P + A+ DP
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA-GLKGSPGSPGNTGLPGFPGFPGAQGDP- 534
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
++G T E +G + + G + +G+ + G K L
Sbjct: 535 ----------GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT-----PGVKGL 579
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP--PP---PQLLPSV-----L 806
P P A S + G + G P P P PP PQ P + +
Sbjct: 580 -------PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632
Query: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
AP P A G E + P PP PP PP P P
Sbjct: 633 PGAPGPPGEAGPRG----ELSVSTPVPGPPGPPGPPGHPGP------------------- 669
Query: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PPG + G+L GD G+ P+ E P + P P G K +
Sbjct: 670 -------QGPPG----IPGSLGKC----GDPGLPGPDGEPGIPGIGF--PGPPGPKGDQG 712
Query: 927 VPLT--SICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
P T S+ P + G GK G P +G+P PG
Sbjct: 713 FPGTKGSLGCPGKM------------------GEPGLPGKPGLPGAKGEPAVAMPGGPGT 754
Query: 985 PAYDPYGPYCPGRASGAGPE----TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
P + PG +G PGL P LP T E L + P Q PP
Sbjct: 755 PGF-------PGERGNSGEHGEIGLPGL-------PGLPGTPGNEGLDGPRGDPGQPGPP 800
Query: 1041 PPPPPP 1046
PP
Sbjct: 801 GEQGPP 806
Score = 95.1 bits (235), Expect = 6e-19
Identities = 221/884 (25%), Positives = 275/884 (31%), Gaps = 211/884 (23%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPP 232
P SP + G P P P + + G G G GP G TP PGPP
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--PGPP 658
Query: 233 DPPPPPRH--------LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP------ 278
PP PP H +P E P + PGPP P
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-----GFPGPPGPKGDQGF 713
Query: 279 --------------ERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324
E LP + + PA A P P P G + G
Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFP--------GERGNSG 765
Query: 325 HRANLACSPLGGGEPSPG-------AGEPSKAGPSGATAGASGRATGPEAAGG------- 370
+ L G +PG G+P + GP G GP A G
Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGL 825
Query: 371 -------GGAGGGG---------GGYRPIIQSPGY--------KTGKGGYGAAAG----- 401
G G G G+ SPG G+ GY G
Sbjct: 826 KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPP 885
Query: 402 ------------GATRPP-PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
GA PP PP + TP + G GA G G +PG
Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPS 945
Query: 449 Q--GLLGPQAYG--QGFGGGQAQDLSKA----PSYSGGPPQP-PSGPPPPGLATCQSYSP 499
+ ++G + +GF G + ++ P G P P+GPP P + +P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNP 1005
Query: 500 DQ-----LQGQLYGVQGEP----------YPGPAAHS-----QGLPTASPSLSYSTGHSP 539
+ + G + G G P +PG A GL YS G P
Sbjct: 1006 GEPGLRGIPGSM-GNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Query: 540 ALSGHGGGWG-PSSLGGGGE----ASPSHIIRPLQSPPATGRPPGVGSPGAPG------- 587
G G G P +G GE P H + P A G P G PG PG
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGPPGH-LGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123
Query: 588 KYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD-GSELLAGPGGPPAERTEDEEFLIQHL 646
K + +L PPG + G +GD G + + GP G E L
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE---------TGL 1174
Query: 647 LQAPSPPR-TSGADGLVGEDGA-----ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHL 700
L+AP PR GA G G+ GA KG G G GP G + P L
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG-----IEGFPGPPGL 1229
Query: 701 QSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFL 760
I + + G + + P G P G S V G K G+
Sbjct: 1230 PGAIIPGQTGNRGPPGS-----------RGSP--GAPGPPGPPGSHVIGIKGDK--GSMG 1274
Query: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
P PP TA P G L G P LP P Q P V +P
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL----- 1327
Query: 821 VHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAM 880
G+ PP P P PP L+ L P +P P P E PG
Sbjct: 1328 ----------GSIGPPGPIGPKGPPGVRGDPGTLKIISL-PGSPGPPGTPGE----PGMQ 1372
Query: 881 QELLGALEPLPPA-PGDTG-VGPPNSEGKDPAGAYRSPSPQGTK 922
EP PP PG+ G GP GKD G +P P G K
Sbjct: 1373 G------EPGPPGPPGNLGPCGPRGKPGKD--GKPGTPGPAGEK 1408
Score = 74.7 bits (182), Expect = 9e-13
Identities = 165/635 (25%), Positives = 202/635 (31%), Gaps = 136/635 (21%)
Query: 124 TPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPPFSPPANGL 182
TPG T + +PG S S G + FP +P +L P P A GL
Sbjct: 110 TPGNTGPYGLVGVPGCS--------------GSKGEQGFPGLPGTLGY---PGIPGAAGL 152
Query: 183 LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLP 242
AP + + G+ G G PP PGP PP PP
Sbjct: 153 KGQKG--------APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG--- 201
Query: 243 TQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPPPERAL------PRQDTVIKH 291
F + ++ G GPP P + P T +K
Sbjct: 202 --FFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAG 350
+ A P PP L G SY S G PG G+P K G
Sbjct: 260 EKGDKGAMGEPGPPGPSGLP-----GESYGSEK-----------GAPGDPGLQGKPGKDG 303
Query: 351 PSG--ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGA----AAGGAT 404
G + G G P G G G G P PG++ Y G
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP----PGFRGPTEYYDTYQEKGDEGTP 359
Query: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGG 464
PP PR P Q GP + +S G G +PG P GL G + +G G
Sbjct: 360 GPPGPRGARGP--QGPSGPPGVPGSPGSSRPGLRG----APGWP-GLKGSKGE-RGRPGK 411
Query: 465 QAQDLSKAPSYSGGPPQPPS-GPP-PPGLATCQSYSPDQ--LQGQLY--------GVQGE 512
A +P +G P P S GPP PPG + P L G L G +GE
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 513 P---------------YPG-PAAHS-QGLP--------TASPSLSYSTGHSPALSGHGGG 547
P PG P H +G+P SP +TG P G G
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG-LPGFPGFPGA 530
Query: 548 WGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
G L G G P + P G+P G G PG + + P P G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPG---TPGVKGLP--GPKGE 585
Query: 606 GSYAAGAGGYKGKGD----GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
+ + G GD GS AGP GPP + E P T G G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE----------PGLQGTQGVPGA 635
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQ 696
G G A L S GPPG P PQ
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670
Score = 57.8 bits (138), Expect = 1e-07
Identities = 179/734 (24%), Positives = 227/734 (30%), Gaps = 126/734 (17%)
Query: 890 LPPAPGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945
LP PG+TG VG P G G P GT +P + L+ ++ +
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSK--GEQGFPGLPGTLGYPGIPGAAG------LKGQKGA 158
Query: 946 FFPTMEEMFGGGAADDYGKAGPPEDEG--DPKAGAGP--PPGPPAY-------DPYGP-- 992
P EE A D G G P +G P GP PPGPP + P GP
Sbjct: 159 --PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216
Query: 993 YCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI-------QSGPHQAAPPPPPPP 1045
+ R G E GL PP P TV G + G A P PP
Sbjct: 217 HMGERVIGHKGERGVKGL--TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 1046 PPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADE 1105
P GL + S K DP Q
Sbjct: 275 P----------SGLPGESYGSEKGAP------------GDPGLQ-------------GKP 299
Query: 1106 DKADVPA-----DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPT 1160
K VP ++ N R P L+ + +G F P D + +G + T
Sbjct: 300 GKDGVPGFPGSEGVKGN-RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358
Query: 1161 KAKRDGPPRPRG-RPRIRPLEVPTTAGPASASTP----TDGAKKPRGRGRGRGRKAEEAG 1215
GPP PRG R P P G +S P G +G RGR ++A
Sbjct: 359 P----GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414
Query: 1216 GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
GT P P G GD + D L I V+ P
Sbjct: 415 GT---PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG-DHGLPGYLGSPGIPGVDG--P 468
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP--PATPAVP 1333
+ + G + + ++ P L P L K +P A GL+ P P +P
Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGL------PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522
Query: 1334 ----HPPPSGAFGLGGAL-EAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
P G GL G E + EG +G P + ++ L+ +P +
Sbjct: 523 GFPGFPGAQGDPGLKGEKGETLQPEGQ-VGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLPGLPSANSN 1445
K DP G + P GPP PG +PG P
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641
Query: 1446 GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 1505
P L P P PP P P P P PP P P P P P P
Sbjct: 642 AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGK----CGDPGLPGPDGEPGIP 697
Query: 1506 PPAMPSPPPPP-----PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCG- 1559
P PP P P L P + P P LP AK + A+ G
Sbjct: 698 GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG------AKGEPAVAMPGG 751
Query: 1560 -ETDEEAGESGGEG 1572
T GE G G
Sbjct: 752 PGTPGFPGERGNSG 765
Score = 53.9 bits (128), Expect = 2e-06
Identities = 231/941 (24%), Positives = 276/941 (29%), Gaps = 230/941 (24%)
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRT-SGADGLVGEDG 666
+ GA G KG+ GP G P ++ F L P P+ G GL G G
Sbjct: 40 FCDGAKGEKGEKG----FPGPPGSPGQKG----FTGPEGLPGPQGPKGFPGLPGLTGSKG 91
Query: 667 AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK 726
S GL G G+ G PGTP Y L V S S E L LG
Sbjct: 92 VRGIS-GLPGFSGSPGLPGTPGNTGP-----YGLVGVPGCSGSKGEQGFPGLPGTLGY-- 143
Query: 727 EKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
G A GA AKE L P P A P P GL G
Sbjct: 144 ----------PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA----PGPQGL---PG 186
Query: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK--VGVHLLEPATRDGAPQPPPPPPPPPP 844
P P + PP P P + P K +G ++ G PP PP
Sbjct: 187 PPGFPGPVGPPGP---PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243
Query: 845 PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
+ + P R + GAM E P PG +G+ P S
Sbjct: 244 VI------------VTLTGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGL-PGES 282
Query: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964
G + GA P QG VP FP S R F M E G G
Sbjct: 283 YGSEK-GAPGDPGLQGKPGKDGVP----GFPGSEGVKGNRGFPGLMGE---DGIKGQKGD 334
Query: 965 AGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE-TPGLGLDPNKPPELPSTVN 1023
GPP G + YD Y G E TPG PP
Sbjct: 335 IGPPGFRGPTEY----------YDTY--------QEKGDEGTPG-------PP------- 362
Query: 1024 AEPLGLIQSGPHQAAPPPPPPPPP--PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLL 1081
GP A P P PP P +P S G +P + K K
Sbjct: 363 ---------GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK---------- 403
Query: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPAL------- 1134
R P +D P C P L
Sbjct: 404 GERGRP----------------GKDAMGTPGS------------PGCAGSPGLPGSPGPP 435
Query: 1135 SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASAS--T 1192
P GDI F PG G P DGP +G P + + P GP
Sbjct: 436 GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---KGEPGLLCTQCPYIPGPPGLPGLP 492
Query: 1193 PTDGAKKPRGRGRGRGRKAEEAG-------------GTRLEP-LKPLKIKLSVPKAGEGL 1238
G K GR G K G + +P LK K + P+ G+
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552
Query: 1239 GTSSG----------DAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDF 1288
G D I GT L K E + EK + G S
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVK---GLPGPKGELALSG--EKGDQGPPGDPGSPGSP 607
Query: 1289 LKSGKRHPPLYQAGLTPPLSPPKSVP--PSVPARGLQ----------PQPPATPAVP-HP 1335
+G PP Y P L + VP P P P PP P P HP
Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667
Query: 1336 PPSGAFGLGGALEAAESEGL----------GLGCPSPC-KRLDEELKRNLETLPSFSSDE 1384
P G G+ G+L GL G+G P P + D+ +L
Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727
Query: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
E + L A +P +A P TP P + G LPGLP
Sbjct: 728 EPGLPGKPGLP-------GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP---- 776
Query: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
G P P E P P QP PP PP + P
Sbjct: 777 -GLPGTPGNEGLDGPRGDPG---QPGPPGEQGPPGRCIEGP 813
Score = 45.8 bits (107), Expect = 4e-04
Identities = 58/213 (27%), Positives = 68/213 (31%), Gaps = 52/213 (24%)
Query: 1404 ALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP-SANSNGTPEPP---------LL 1453
A+ D GP GPP P A +PG G P S S G P PP +
Sbjct: 1208 AMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 1454 EEK-----PPPTPPPAPTPQPQPPPP-PPPPQPALPSPP--------PLVAPTPSSP--- 1496
+K P P PP PP P P LP P P V +P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL 1327
Query: 1497 ----PPPPLPPPPPPAM-------------PSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
PP P+ P PP + SP PP P + P P P P
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387
Query: 1540 LPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
P +P K T AGE G +G
Sbjct: 1388 GPRGKPGKDGKP--------GTPGPAGEKGNKG 1412
Score = 39.7 bits (91), Expect = 0.030
Identities = 63/251 (25%), Positives = 75/251 (29%), Gaps = 49/251 (19%)
Query: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
PP + P+ P P P +P +P P P G G G +GL LG P
Sbjct: 1090 PPGHLGPAGPEGA--PGSPGSPGLPGKPGPHGDLGFKGI------KGL-LGPPGI----- 1135
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL--AGPKDTSTPDGPPLA 1425
R LP F + ++ I + L A P P
Sbjct: 1136 ----RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
PG P LPG A + P PT P PP P +P
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPR--------------GPTGIEGFPGPPGLPGAIIPGQ 1237
Query: 1486 PPLVAPTPSSPPPPPLPPPPPP------------AMPSPPPPPPPAAAPLAAPPEEPAAP 1533
P S P PP PP +M P P PP A PP AP
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Query: 1534 SPEDPELPDTR 1544
P LP R
Sbjct: 1298 G--TPGLPGPR 1306
Score = 32.3 bits (72), Expect = 4.9
Identities = 33/115 (28%), Positives = 38/115 (33%), Gaps = 24/115 (20%)
Query: 1431 PGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPAPTPQPQPPPP---------PPPPQP 1480
PG PGLP + G P E P PP PT P P P PP
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGH 1093
Query: 1481 ALPSPPPLVAPTPSSPPPPPLPPP-------------PPPAMPSPPPPPPPAAAP 1522
P+ P +P SP P P P PP + PP P +P
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148
Score = 31.6 bits (70), Expect = 8.3
Identities = 41/153 (26%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 1697 PAPPPKPET--PEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPL 1754
P PP P P +T + PP P PP P ++ + +K + G
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI-----GIKGDKGSMGHPGP 1278
Query: 1755 RGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK----WLKEAGGNAT 1810
+G T+G P R G P T LP R P K +K +L G
Sbjct: 1279 KGPPGTAGDMGPPGR---LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335
Query: 1811 AG-GGPPGSSSD-----------SESSPGAPSE 1831
G GPPG D S PG P E
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 120 bits (302), Expect = 1e-26
Identities = 230/898 (25%), Positives = 281/898 (31%), Gaps = 204/898 (22%)
Query: 199 VPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAA 257
+P + G + L G G L +G Q PP PG P P P A +
Sbjct: 570 IPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGP-----------AGPAGPPGY 618
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH-ALQHYLSC 316
Q P L G P PP A PR + + P P PP PP H Q
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS---TPVPGPPGPPGPPGHPGPQGPPGI 675
Query: 317 GGSYPSMGHRANLACSPLGGGEPS-PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGG 375
GS G P GEP PG G P GP G
Sbjct: 676 PGSLGKCGDPG----LPGPDGEPGIPGIGFPGPPGPKGDQ-------------------- 711
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGA 435
G G + + PG K G+ G +P P + P GGP G+ G
Sbjct: 712 GFPGTKGSLGCPG-KMGEPGLPG------KPGLPGAKGEPAVAMPGGPGTPGFPGER-GN 763
Query: 436 GGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQ 495
G G+ PG P G G + P G P PP PPG
Sbjct: 764 SGEHGEIGLPGLP-----------GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812
Query: 496 SYSPDQLQGQ--LYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSL 553
L G L G QG G+P S SP + GH G GP
Sbjct: 813 PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872
Query: 554 GGG-------GEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G G +I + P A G P G+PG PG+ S + PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI--------PGVK 924
Query: 607 SYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG 666
G +GD PG P+E I H++ P G G GE G
Sbjct: 925 GQRGTPGAKGEQGDKGN----PG--PSE--------ISHVIGDKGEPGLKGFAGNPGEKG 970
Query: 667 -----AADASKGLGGSGGAGGPPGTPYELAKE-DPQRYHLQSVIRTSASLDEGATAALEL 720
KGL G G GPPG +L +P L+ + + ++ +
Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030
Query: 721 GLGRLKEKKKGPERGGETPEGLATSVVHYGAGAK-ELGAFLQKSPPPPPPTAQSTQPTPH 779
LG P R G GL +H G K E G P PP PT P
Sbjct: 1031 TLGF-------PGRAGRP--GLPG--IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079
Query: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
G E G P PP L PA +GAP P P
Sbjct: 1080 GKKGEMGQPG-------PPGH-----------------------LGPAGPEGAPGSPGSP 1109
Query: 840 PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV 899
P P P L G++ P +R PPG L P +PG G+
Sbjct: 1110 GLPGKPGP---HGDLGFKGIKGLLGPPGIR-----GPPG--------LPGFPGSPGPMGI 1153
Query: 900 ----------GPPNSEG-----KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEER 944
GP +G + P G +P QG K R P
Sbjct: 1154 RGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP---------------- 1197
Query: 945 SFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE 1004
FP + GA D G GP EG P PPG P G PG+ GP
Sbjct: 1198 -GFPGLPGR--KGAMGDAGPRGPTGIEGFP-----GPPGLP-----GAIIPGQTGNRGP- 1243
Query: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
PG P P P + +G+ G + P P PP A P G L +P
Sbjct: 1244 -PGSRGSPGAPGP-PGPPGSHVIGI--KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Score = 101 bits (251), Expect = 9e-21
Identities = 235/906 (25%), Positives = 294/906 (32%), Gaps = 187/906 (20%)
Query: 173 PPFSPPANGLLSPHDVLHLK-PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGP 231
PP SP G P + + P P +P G + GV G +GL P PG
Sbjct: 56 PPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGFSGSPGLPGT 110
Query: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291
P P + L+ + + EQ P L G PG P ++ K
Sbjct: 111 PGNTGP-------YGLVGVPGCSGSKGEQGFPGLPGTLGY-PGIPGAAGLKGQKGAPAKE 162
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGP 351
A+ P P A Q G +P P+G P G P GP
Sbjct: 163 EDIELDAKGDPGLPGAPGPQGLPGPPG-FPG----------PVGPPGPPGFFGFPGAMGP 211
Query: 352 SGATAGASGRATGPEAAGG----GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP 407
G R G + G G G G + P +T G G P
Sbjct: 212 RGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPG 271
Query: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQ 467
PP + P +S G A G G G PG +G+ G +GF G +
Sbjct: 272 PPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGS-EGVKG----NRGFPGLMGE 325
Query: 468 DLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA 527
D K GPP GP + Y Q +G G G P P A QG P+
Sbjct: 326 DGIKGQKGDIGPPGF-RGPT-------EYYDTYQEKGD-EGTPGPPGPRGARGPQG-PSG 375
Query: 528 SPSLSYSTGHS-PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG-VGSPGA 585
P + S G S P L G GW P G GE RP + T PG GSPG
Sbjct: 376 PPGVPGSPGSSRPGLRG-APGW-PGLKGSKGERG-----RPGKDAMGTPGSPGCAGSPGL 428
Query: 586 PGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPPAERTEDEEFLI 643
PG P PPG + G G G GS + G GP E L
Sbjct: 429 PGS------PGPP--GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE----PGLLC 476
Query: 644 QHLLQAPSPPRTSGADGL------VGEDGAADASKGLGGSGGAGGPPGTP-YELAKEDPQ 696
P PP G GL G GAA KG GS G G PG P + A+ DP
Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA-GLKGSPGSPGNTGLPGFPGFPGAQGDP- 534
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
++G T E +G + + G + +G+ + G K L
Sbjct: 535 ----------GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT-----PGVKGL 579
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPP--PP---PQLLPSV-----L 806
P P A S + G + G P P P PP PQ P + +
Sbjct: 580 -------PGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632
Query: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
AP P A G E + P PP PP PP P P
Sbjct: 633 PGAPGPPGEAGPRG----ELSVSTPVPGPPGPPGPPGHPGP------------------- 669
Query: 867 RLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF 926
PPG + G+L GD G+ P+ E P + P P G K +
Sbjct: 670 -------QGPPG----IPGSLGKC----GDPGLPGPDGEPGIPGIGF--PGPPGPKGDQG 712
Query: 927 VPLT--SICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGP 984
P T S+ P + G GK G P +G+P PG
Sbjct: 713 FPGTKGSLGCPGKM------------------GEPGLPGKPGLPGAKGEPAVAMPGGPGT 754
Query: 985 PAYDPYGPYCPGRASGAGPE----TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
P + PG +G PGL P LP T E L + P Q PP
Sbjct: 755 PGF-------PGERGNSGEHGEIGLPGL-------PGLPGTPGNEGLDGPRGDPGQPGPP 800
Query: 1041 PPPPPP 1046
PP
Sbjct: 801 GEQGPP 806
Score = 95.1 bits (235), Expect = 6e-19
Identities = 221/884 (25%), Positives = 275/884 (31%), Gaps = 211/884 (23%)
Query: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG-GVLGPAGLGPAQTPPYRPGPP 232
P SP + G P P P + + G G G GP G TP PGPP
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV--PGPP 658
Query: 233 DPPPPPRH--------LPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP------ 278
PP PP H +P E P + PGPP P
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI-----GFPGPPGPKGDQGF 713
Query: 279 --------------ERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMG 324
E LP + + PA A P P P G + G
Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFP--------GERGNSG 765
Query: 325 HRANLACSPLGGGEPSPG-------AGEPSKAGPSGATAGASGRATGPEAAGG------- 370
+ L G +PG G+P + GP G GP A G
Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGL 825
Query: 371 -------GGAGGGG---------GGYRPIIQSPGY--------KTGKGGYGAAAG----- 401
G G G G+ SPG G+ GY G
Sbjct: 826 KGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPP 885
Query: 402 ------------GATRPP-PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
GA PP PP + TP + G GA G G +PG
Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPS 945
Query: 449 Q--GLLGPQAYG--QGFGGGQAQDLSKA----PSYSGGPPQP-PSGPPPPGLATCQSYSP 499
+ ++G + +GF G + ++ P G P P+GPP P + +P
Sbjct: 946 EISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNP 1005
Query: 500 DQ-----LQGQLYGVQGEP----------YPGPAAHS-----QGLPTASPSLSYSTGHSP 539
+ + G + G G P +PG A GL YS G P
Sbjct: 1006 GEPGLRGIPGSM-GNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Query: 540 ALSGHGGGWG-PSSLGGGGE----ASPSHIIRPLQSPPATGRPPGVGSPGAPG------- 587
G G G P +G GE P H + P A G P G PG PG
Sbjct: 1065 GPPGPTGDPGLPGDMGKKGEMGQPGPPGH-LGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123
Query: 588 KYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD-GSELLAGPGGPPAERTEDEEFLIQHL 646
K + +L PPG + G +GD G + + GP G E L
Sbjct: 1124 KGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE---------TGL 1174
Query: 647 LQAPSPPR-TSGADGLVGEDGA-----ADASKGLGGSGGAGGPPGTPYELAKEDPQRYHL 700
L+AP PR GA G G+ GA KG G G GP G + P L
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG-----IEGFPGPPGL 1229
Query: 701 QSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFL 760
I + + G + + P G P G S V G K G+
Sbjct: 1230 PGAIIPGQTGNRGPPGS-----------RGSP--GAPGPPGPPGSHVIGIKGDK--GSMG 1274
Query: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
P PP TA P G L G P LP P Q P V +P
Sbjct: 1275 HPGPKGPPGTAGDMGPP--GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL----- 1327
Query: 821 VHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAM 880
G+ PP P P PP L+ L P +P P P E PG
Sbjct: 1328 ----------GSIGPPGPIGPKGPPGVRGDPGTLKIISL-PGSPGPPGTPGE----PGMQ 1372
Query: 881 QELLGALEPLPPA-PGDTG-VGPPNSEGKDPAGAYRSPSPQGTK 922
EP PP PG+ G GP GKD G +P P G K
Sbjct: 1373 G------EPGPPGPPGNLGPCGPRGKPGKD--GKPGTPGPAGEK 1408
Score = 74.7 bits (182), Expect = 9e-13
Identities = 165/635 (25%), Positives = 202/635 (31%), Gaps = 136/635 (21%)
Query: 124 TPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPPFSPPANGL 182
TPG T + +PG S S G + FP +P +L P P A GL
Sbjct: 110 TPGNTGPYGLVGVPGCS--------------GSKGEQGFPGLPGTLGY---PGIPGAAGL 152
Query: 183 LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLP 242
AP + + G+ G G PP PGP PP PP
Sbjct: 153 KGQKG--------APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPG--- 201
Query: 243 TQFNLLASSSAAAAAAEQSSPQLYNFSG-----AAPGPPPPERAL------PRQDTVIKH 291
F + ++ G GPP P + P T +K
Sbjct: 202 --FFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259
Query: 292 YQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAG 350
+ A P PP L G SY S G PG G+P K G
Sbjct: 260 EKGDKGAMGEPGPPGPSGLP-----GESYGSEK-----------GAPGDPGLQGKPGKDG 303
Query: 351 PSG--ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGA----AAGGAT 404
G + G G P G G G G P PG++ Y G
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP----PGFRGPTEYYDTYQEKGDEGTP 359
Query: 405 RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGG 464
PP PR P Q GP + +S G G +PG P GL G + +G G
Sbjct: 360 GPPGPRGARGP--QGPSGPPGVPGSPGSSRPGLRG----APGWP-GLKGSKGE-RGRPGK 411
Query: 465 QAQDLSKAPSYSGGPPQPPS-GPP-PPGLATCQSYSPDQ--LQGQLY--------GVQGE 512
A +P +G P P S GPP PPG + P L G L G +GE
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 513 P---------------YPG-PAAHS-QGLP--------TASPSLSYSTGHSPALSGHGGG 547
P PG P H +G+P SP +TG P G G
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTG-LPGFPGFPGA 530
Query: 548 WGPSSLGG--GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
G L G G P + P G+P G G PG + + P P G
Sbjct: 531 QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPG---TPGVKGLP--GPKGE 585
Query: 606 GSYAAGAGGYKGKGD----GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGL 661
+ + G GD GS AGP GPP + E P T G G
Sbjct: 586 LALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE----------PGLQGTQGVPGA 635
Query: 662 VGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQ 696
G G A L S GPPG P PQ
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ 670
Score = 57.8 bits (138), Expect = 1e-07
Identities = 179/734 (24%), Positives = 227/734 (30%), Gaps = 126/734 (17%)
Query: 890 LPPAPGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERS 945
LP PG+TG VG P G G P GT +P + L+ ++ +
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSK--GEQGFPGLPGTLGYPGIPGAAG------LKGQKGA 158
Query: 946 FFPTMEEMFGGGAADDYGKAGPPEDEG--DPKAGAGP--PPGPPAY-------DPYGP-- 992
P EE A D G G P +G P GP PPGPP + P GP
Sbjct: 159 --PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216
Query: 993 YCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI-------QSGPHQAAPPPPPPP 1045
+ R G E GL PP P TV G + G A P PP
Sbjct: 217 HMGERVIGHKGERGVKGL--TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274
Query: 1046 PPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADE 1105
P GL + S K DP Q
Sbjct: 275 P----------SGLPGESYGSEKGAP------------GDPGLQ-------------GKP 299
Query: 1106 DKADVPA-----DIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPT 1160
K VP ++ N R P L+ + +G F P D + +G + T
Sbjct: 300 GKDGVPGFPGSEGVKGN-RGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358
Query: 1161 KAKRDGPPRPRG-RPRIRPLEVPTTAGPASASTP----TDGAKKPRGRGRGRGRKAEEAG 1215
GPP PRG R P P G +S P G +G RGR ++A
Sbjct: 359 P----GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAM 414
Query: 1216 GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
GT P P G GD + D L I V+ P
Sbjct: 415 GT---PGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG-DHGLPGYLGSPGIPGVDG--P 468
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP--PATPAVP 1333
+ + G + + ++ P L P L K +P A GL+ P P +P
Sbjct: 469 KGEPGLLCTQCPYIPGPPGLPGL------PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522
Query: 1334 ----HPPPSGAFGLGGAL-EAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
P G GL G E + EG +G P + ++ L+ +P +
Sbjct: 523 GFPGFPGAQGDPGLKGEKGETLQPEGQ-VGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLPGLPSANSN 1445
K DP G + P GPP PG +PG P
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641
Query: 1446 GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP 1505
P L P P PP P P P P PP P P P P P P
Sbjct: 642 AGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGK----CGDPGLPGPDGEPGIP 697
Query: 1506 PPAMPSPPPPP-----PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCG- 1559
P PP P P L P + P P LP AK + A+ G
Sbjct: 698 GIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPG------AKGEPAVAMPGG 751
Query: 1560 -ETDEEAGESGGEG 1572
T GE G G
Sbjct: 752 PGTPGFPGERGNSG 765
Score = 53.9 bits (128), Expect = 2e-06
Identities = 231/941 (24%), Positives = 276/941 (29%), Gaps = 230/941 (24%)
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRT-SGADGLVGEDG 666
+ GA G KG+ GP G P ++ F L P P+ G GL G G
Sbjct: 40 FCDGAKGEKGEKG----FPGPPGSPGQKG----FTGPEGLPGPQGPKGFPGLPGLTGSKG 91
Query: 667 AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK 726
S GL G G+ G PGTP Y L V S S E L LG
Sbjct: 92 VRGIS-GLPGFSGSPGLPGTPGNTGP-----YGLVGVPGCSGSKGEQGFPGLPGTLGY-- 143
Query: 727 EKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
G A GA AKE L P P A P P GL G
Sbjct: 144 ----------PGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA----PGPQGL---PG 186
Query: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK--VGVHLLEPATRDGAPQPPPPPPPPPP 844
P P + PP P P + P K +G ++ G PP PP
Sbjct: 187 PPGFPGPVGPPGP---PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243
Query: 845 PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
+ + P R + GAM E P PG +G+ P S
Sbjct: 244 VI------------VTLTGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGL-PGES 282
Query: 905 EGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGK 964
G + GA P QG VP FP S R F M E G G
Sbjct: 283 YGSEK-GAPGDPGLQGKPGKDGVP----GFPGSEGVKGNRGFPGLMGE---DGIKGQKGD 334
Query: 965 AGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPE-TPGLGLDPNKPPELPSTVN 1023
GPP G + YD Y G E TPG PP
Sbjct: 335 IGPPGFRGPTEY----------YDTY--------QEKGDEGTPG-------PP------- 362
Query: 1024 AEPLGLIQSGPHQAAPPPPPPPPP--PPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLL 1081
GP A P P PP P +P S G +P + K K
Sbjct: 363 ---------GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSK---------- 403
Query: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPAL------- 1134
R P +D P C P L
Sbjct: 404 GERGRP----------------GKDAMGTPGS------------PGCAGSPGLPGSPGPP 435
Query: 1135 SPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASAS--T 1192
P GDI F PG G P DGP +G P + + P GP
Sbjct: 436 GPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGP---KGEPGLLCTQCPYIPGPPGLPGLP 492
Query: 1193 PTDGAKKPRGRGRGRGRKAEEAG-------------GTRLEP-LKPLKIKLSVPKAGEGL 1238
G K GR G K G + +P LK K + P+ G+
Sbjct: 493 GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552
Query: 1239 GTSSG----------DAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDF 1288
G D I GT L K E + EK + G S
Sbjct: 553 PGDPGLRGQPGRKGLDGIPGTPGVK---GLPGPKGELALSG--EKGDQGPPGDPGSPGSP 607
Query: 1289 LKSGKRHPPLYQAGLTPPLSPPKSVP--PSVPARGLQ----------PQPPATPAVP-HP 1335
+G PP Y P L + VP P P P PP P P HP
Sbjct: 608 GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP 667
Query: 1336 PPSGAFGLGGALEAAESEGL----------GLGCPSPC-KRLDEELKRNLETLPSFSSDE 1384
P G G+ G+L GL G+G P P + D+ +L
Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727
Query: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
E + L A +P +A P TP P + G LPGLP
Sbjct: 728 EPGLPGKPGLP-------GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP---- 776
Query: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
G P P E P P QP PP PP + P
Sbjct: 777 -GLPGTPGNEGLDGPRGDPG---QPGPPGEQGPPGRCIEGP 813
Score = 45.8 bits (107), Expect = 4e-04
Identities = 58/213 (27%), Positives = 68/213 (31%), Gaps = 52/213 (24%)
Query: 1404 ALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLP-SANSNGTPEPP---------LL 1453
A+ D GP GPP P A +PG G P S S G P PP +
Sbjct: 1208 AMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIK 1267
Query: 1454 EEK-----PPPTPPPAPTPQPQPPPP-PPPPQPALPSPP--------PLVAPTPSSP--- 1496
+K P P PP PP P P LP P P V +P
Sbjct: 1268 GDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFL 1327
Query: 1497 ----PPPPLPPPPPPAM-------------PSPPPPPPPAAAPLAAPPEEPAAPSPEDPE 1539
PP P+ P PP + SP PP P + P P P P
Sbjct: 1328 GSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387
Query: 1540 LPDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572
P +P K T AGE G +G
Sbjct: 1388 GPRGKPGKDGKP--------GTPGPAGEKGNKG 1412
Score = 39.7 bits (91), Expect = 0.030
Identities = 63/251 (25%), Positives = 75/251 (29%), Gaps = 49/251 (19%)
Query: 1309 PPKSVPPSVPARGLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
PP + P+ P P P +P +P P P G G G +GL LG P
Sbjct: 1090 PPGHLGPAGPEGA--PGSPGSPGLPGKPGPHGDLGFKGI------KGL-LGPPGI----- 1135
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPL--AGPKDTSTPDGPPLA 1425
R LP F + ++ I + L A P P
Sbjct: 1136 ----RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191
Query: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
PG P LPG A + P PT P PP P +P
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPR--------------GPTGIEGFPGPPGLPGAIIPGQ 1237
Query: 1486 PPLVAPTPSSPPPPPLPPPPPP------------AMPSPPPPPPPAAAPLAAPPEEPAAP 1533
P S P PP PP +M P P PP A PP AP
Sbjct: 1238 TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1297
Query: 1534 SPEDPELPDTR 1544
P LP R
Sbjct: 1298 G--TPGLPGPR 1306
Score = 32.3 bits (72), Expect = 4.9
Identities = 33/115 (28%), Positives = 38/115 (33%), Gaps = 24/115 (20%)
Query: 1431 PGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPAPTPQPQPPPP---------PPPPQP 1480
PG PGLP + G P E P PP PT P P P PP
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPP-GPTGDPGLPGDMGKKGEMGQPGPPGH 1093
Query: 1481 ALPSPPPLVAPTPSSPPPPPLPPP-------------PPPAMPSPPPPPPPAAAP 1522
P+ P +P SP P P P PP + PP P +P
Sbjct: 1094 LGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148
Score = 31.6 bits (70), Expect = 8.3
Identities = 41/153 (26%), Positives = 52/153 (33%), Gaps = 26/153 (16%)
Query: 1697 PAPPPKPET--PEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPL 1754
P PP P P +T + PP P PP P ++ + +K + G
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI-----GIKGDKGSMGHPGP 1278
Query: 1755 RGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKK----WLKEAGGNAT 1810
+G T+G P R G P T LP R P K +K +L G
Sbjct: 1279 KGPPGTAGDMGPPGR---LGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335
Query: 1811 AG-GGPPGSSSD-----------SESSPGAPSE 1831
G GPPG D S PG P E
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 118 bits (295), Expect = 7e-26
Identities = 345/1328 (25%), Positives = 417/1328 (31%), Gaps = 261/1328 (19%)
Query: 299 QPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGA 358
+PPPPPPP Q + G N +C P+ GE AGP G G
Sbjct: 450 EPPPPPPP----QRPPTPGSEQIGFLKTINCSC-------PAGEKGEMGVAGPMG-LPGP 497
Query: 359 SG--RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPK 416
G A GP A G G G P Q G K KG G P PP +
Sbjct: 498 KGDIGAIGPVGAPGPKGEKGDVGIGPFGQ--GEKGEKGSLGL-------PGPPGRDGSKG 548
Query: 417 CQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQ----------------- 459
+ G G G G PG P + P G+
Sbjct: 549 MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDG 608
Query: 460 --GFGGGQAQDLSKAPSYSGGPPQP-----PSGPP-PPGLATCQSYSPDQLQGQLYGVQG 511
G G Q PS GP P+GPP PG S Q +G L G QG
Sbjct: 609 FPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG-------SVVQQEG-LKGEQG 660
Query: 512 EPYPGPAAHSQGLPTASPSLSYSTGHSP----ALSGHGGGWGPSSLGGGGEASPSHIIRP 567
P P + G P A + P L G G GP + G +
Sbjct: 661 APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPG---------LLG 711
Query: 568 LQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAG 627
LQ PP PPGV PG PG PG G G+ GK G
Sbjct: 712 LQGPPG---PPGV--PGPPG---------------PGGSPGLPGEIGFPGKPGP----PG 747
Query: 628 PGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP 687
P GPP + + P PP T G G GEDG GL G G G G P
Sbjct: 748 PTGPPGKDGPN---------GPPGPPGTKGEPGERGEDG-LPGKPGLRGEIGEQGLAGRP 797
Query: 688 YELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK-EKKKGPERGGETPEGLATSV 746
E + +R D+G ELGL LK ++ + E G P GL
Sbjct: 798 GEKGEAGLPGAPGFPGVRGEKG-DQGEKG--ELGLPGLKGDRGEKGEAGPAGPPGLP--- 851
Query: 747 VHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVL 806
G +P P P Q P G E G P LP P Q P L
Sbjct: 852 ----------GTTSLFTPHPRMPGEQG----PKG---EKGDPGLP---GEPGLQGRPGEL 891
Query: 807 S-HAPSPSPSA-SKVGVHLLEPAT-RDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAA 863
P+ P A + G H A GAP P P PP + + GL
Sbjct: 892 GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP------GSVGAPGLRGTP 945
Query: 864 PSPRLRPEESLDPPGAMQELLGALEPLPPA--PGDTGVGPPNSEGKDPAGAYRS----PS 917
R E+ GA E G+ P+ P PG G+ P +GKD R P
Sbjct: 946 GKDGERGEK-----GAAGE-EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
Query: 918 PQGTKAP-RFVPLTSICFPDSLLQDEERSF-----FPTMEEMFGGGAADDYGKAGPPEDE 971
P GTKA V + C +R P G G A G +GPP D+
Sbjct: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDK 1059
Query: 972 GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQ 1031
G P G+ PG P GP P GA P PG P K P L S ++ + L+
Sbjct: 1060 GSP--GSRGLPGFP-----GPQGPAGRDGA-PGNPGERGPPGK-PGLSSLLSPGDINLLA 1110
Query: 1032 SGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP 1091
PP PP P P + KG P T+ K K + P P
Sbjct: 1111 KDVCNDCPPGPPGLPGLPGFKGD-KGVPGKPGREGTEGK---KGEAGPPGLPGPPGIAGP 1166
Query: 1092 KKLYAQ-----EYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPN 1146
+ + E + D+ VP + P P + A P G I P
Sbjct: 1167 QGSQGERGADGEVGQKGDQGHPGVPG--FMGPPGNPGPPGADGIAGAAGPPG-IQGSPGK 1223
Query: 1147 PGPDGPRRRGRKP------TKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTP------- 1193
GP GP+ P K RDG P P G P P GP A P
Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP--GKAGEPGLPGPEGARGPPGFKGHT 1281
Query: 1194 -TDGAKKPRGRGRGRGRKAEEA-----GGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAIS 1247
GA PRG G +E G T + + P G+ S
Sbjct: 1282 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341
Query: 1248 GT-------DHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQ 1300
GT N E EK K G + G+R P +
Sbjct: 1342 GTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIK 1401
Query: 1301 AGLTPPLSPPKSVPPSVPAR-------GLQPQPPATPAVPHPPPSGAFGLGGAL-EAAES 1352
PP + P +P G Q P V P P G G G E+
Sbjct: 1402 GDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 1461
Query: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412
E L + + EEL + LET ++ L P A
Sbjct: 1462 ETLR-------RLIQEELGKQLETRLAY-----------------------LLAQMPPAY 1491
Query: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPS-ANSNGTPEPPLLEEKPPPTPPPAPTPQPQP 1471
K + GP PGPP GLP A G P P P+ P P +
Sbjct: 1492 MKSSQGRPGP--------PGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543
Query: 1472 PPPPPPPQPAL---PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAP-LAAPP 1527
P P L PP + P P P P +P P PA P L PP
Sbjct: 1544 KGDPGAPGVGLRGEMGPPGI----PGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP 1599
Query: 1528 EEPAAPSP 1535
P P
Sbjct: 1600 GPPGQCDP 1607
Score = 114 bits (285), Expect = 1e-24
Identities = 271/1077 (25%), Positives = 332/1077 (30%), Gaps = 257/1077 (23%)
Query: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220
P +P L LQ PP P G+ P P +P +P +GF G GP G
Sbjct: 703 PPGIPGLLGLQGPPGPP---GVPGPPG-----PGGSPGLPGEIGFPGKPGPP--GPTG-- 750
Query: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
PP + GP PP PP E+ L PG P
Sbjct: 751 ----PPGKDGPNGPPGPP-------------GTKGEPGERGEDGL-------PGKPGLRG 786
Query: 281 ALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPS 340
+ Q + ++ + P P P G G + L L G
Sbjct: 787 EIGEQGLAGRPGEKGEAGLPGAPGFPG--------VRGEKGDQGEKGELGLPGLKGDRGE 838
Query: 341 PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
G P AGP G S P G G G G + PG + G G
Sbjct: 839 KGEAGP--AGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD-PGLPGEPGLQGRPGELGPQ- 894
Query: 401 GGATRPPPPRSTATPKCQSLGGPAAAYATGKAS--GAGGAGGQAYSPGQPQGLLG-PQAY 457
G T PP + G P AA G GA G G S G P GL G P
Sbjct: 895 -GPTGPPGAKGQEGAH----GAPGAAGNPGAPGHVGAPGPSGPPGSVGAP-GLRGTPGKD 948
Query: 458 GQ-GFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEP-YP 515
G+ G G ++ S P G P P P PPG + P G++G P P
Sbjct: 949 GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG--KDGEP--------GLRGSPGLP 998
Query: 516 GPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATG 575
GP S + + G G P S G G+ + PP
Sbjct: 999 GPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIG-----VAGPPGPS 1053
Query: 576 RPPG-VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPP 632
PPG GSPG+ G L P P A G G +G G L PG
Sbjct: 1054 GPPGDKGSPGSRG------LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG--- 1104
Query: 633 AERTEDEEFLIQHLLQ--APSPPRTSGADGLVGEDGAAD--ASKGLGGSGGAGGPPGTPY 688
D L + + P PP G G G+ G +G G G GPPG P
Sbjct: 1105 -----DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG 1159
Query: 689 ELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVH 748
PQ +G ERG + G H
Sbjct: 1160 PPGIAGPQG-------------SQG-------------------ERGADGEVGQKGDQGH 1187
Query: 749 YGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDL---PLVLPPPPPQLLPSV 805
G + F+ P PP A G+ AG P + P PP PQ PS
Sbjct: 1188 PG-----VPGFMGPPGNPGPPGAD-------GIAGAAGPPGIQGSPGKEGPPGPQG-PSG 1234
Query: 806 LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP-----PPPPPPMPLQLEAHLRSHGLE 860
L P K G RDG P PP P P P P + + H +
Sbjct: 1235 LPGIPGEE---GKEG--------RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283
Query: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG-VGPPNSEG-KDPAGAYRSPSP 918
AP PR GAM L E LP GDTG GP +G + P G SP
Sbjct: 1284 SGAPGPR-------GESGAMG--LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS 1334
Query: 919 QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP---- 974
G P P + E G G GPP + G+
Sbjct: 1335 PGEPGPSGTPGQK----------------GSKGENGSPGLPGFLGPRGPPGEPGEKGVPG 1378
Query: 975 KAGAGPPPGPPAY-----DPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGL 1029
K G PG P + DP G G G PG DP P T P GL
Sbjct: 1379 KEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ--PG---DPGIPGHKGHTGLMGPQGL 1433
Query: 1030 IQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
P + P PP PP P F LR P +
Sbjct: 1434 ----PGENGPVGPPGPPGQPG---------------------------FPGLRGESPSME 1462
Query: 1090 TPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGP 1149
T ++L +E + + A + A + P + S + RP GP
Sbjct: 1463 TLRRLIQEELGKQLETRLAYLLAQMP------PAYMKSSQGRP---------------GP 1501
Query: 1150 DGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRG 1206
GP + P +A GP GRP LE P +GP P G G
Sbjct: 1502 PGPPGKDGLPGRA---GPMGEPGRPGQGGLEGP--SGPIGPKGERGAKGDPGAPGVG 1553
Score = 94.4 bits (233), Expect = 1e-18
Identities = 260/1065 (24%), Positives = 331/1065 (31%), Gaps = 192/1065 (18%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G+ G G+ Q PP PGPP P L E+ L F G
Sbjct: 560 GLPGEVGMRGPQGPPGLPGPPGRVGAP-------GLQGERGEKGTRGEKGERGLDGFPGK 612
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
PG ++ P V P PP ++ G + G R +
Sbjct: 613 -PGDTG-QQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQ-- 668
Query: 332 SPLGGGEPSPGA----GEPSKAGPSGATA--GASGRATGPEAAGGGGAGGGGGGYRPIIQ 385
G PGA G + GP G G G P G G G G P +
Sbjct: 669 ----GAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP--PGVP 722
Query: 386 SPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSP 445
P G G G +P PP T P GP T G G G+ P
Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT---KGEPGERGEDGLP 779
Query: 446 GQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQ 505
G+P GL G + QG G + G P P PG+ + ++ +
Sbjct: 780 GKP-GLRG-EIGEQGLAGRPGEK---------GEAGLPGAPGFPGVRGEKGDQGEKGELG 828
Query: 506 LYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWG----------PSSLGG 555
L G++G+ A G P + S T H P + G G G P G
Sbjct: 829 LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH-PRMPGEQGPKGEKGDPGLPGEPGLQGR 887
Query: 556 GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGY 615
GE P P P A G+ G+PGA G + AP + P A G G
Sbjct: 888 PGELGPQ---GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 944
Query: 616 KGKGD--GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPR-TSGADGLVGEDG-AADAS 671
GK G + AG G P P PR GA GL G G D
Sbjct: 945 PGKDGERGEKGAAGEEGSP----------------GPVGPRGDPGAPGLPGPPGKGKDGE 988
Query: 672 KGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAAL----ELGLGRLKE 727
GL GS G GP GT K +R S + G G+
Sbjct: 989 PGLRGSPGLPGPLGTKAACGK-----------VRGSENCALGGQCVKGDRGAPGIPGSPG 1037
Query: 728 KKKGPERGGETPEGLATSVVHYGA-GAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
+ P G P G + G+ G++ L F P P P + P G G
Sbjct: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGF----PGPQGPAGRDGAPGNPGERGPPG 1093
Query: 787 GPDLPLVLPPPPPQLLPSVLSHAPSPSPSA--------------SKVGVHLLEPATRDGA 832
P L +L P LL + + P P K G E +
Sbjct: 1094 KPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
Query: 833 PQPPPPPPPPPPPMPLQ------LEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGA 886
P P PP P Q E + P P + P + PPGA + GA
Sbjct: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG-FMGPPGNPGPPGA-DGIAGA 1211
Query: 887 LEP--------------------LPPAPGDTG-------VGPPNSEGKDPAGAYRSPSPQ 919
P LP PG+ G GPP GK AG P P+
Sbjct: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK--AGEPGLPGPE 1269
Query: 920 GTKA-PRFVPLTSICFPDSLLQDEERSFFPTMEEMFG-GGAADDYGKAGPPEDEGDP-KA 976
G + P F T + P E + G G G GP G P K
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKN 1329
Query: 977 GAGPPPGPPAYDPYGPYCPGRASGAG----PETPGLGLDPNKPPELPSTVN--------- 1023
G+ PG P P G PG+ G P PG L P PP P
Sbjct: 1330 GSPGSPGEPG--PSG--TPGQKGSKGENGSPGLPGF-LGPRGPPGEPGEKGVPGKEGVPG 1384
Query: 1024 --AEPLGLIQSGPHQAAPPPPPP-----PPPPPAPASEPKGGLTSPIFCSTK-----PKK 1071
EP + G PP P P P + GL P + P
Sbjct: 1385 KPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
Query: 1072 LLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSR 1131
F LR P +T ++L +E + + A + A + P + S + R
Sbjct: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP------PAYMKSSQGR 1498
Query: 1132 PALSPLGDIDFCPPN----PGPDGPRRRGRKPTKAKRDGPPRPRG 1172
P P G PP PG GP +P + +GP P G
Sbjct: 1499 P--GPPG-----PPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 1536
Score = 89.0 bits (219), Expect = 4e-17
Identities = 193/742 (26%), Positives = 229/742 (30%), Gaps = 130/742 (17%)
Query: 195 QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPP-----PPPRHLPTQFNLLA 249
Q PT P + A G G AG A PGP PP P R P +
Sbjct: 894 QGPTGPPGAKGQEGAHGAP-GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG--- 949
Query: 250 SSSAAAAAAEQSSPQLYNFSG--AAPG-PPPPERALPRQDTVIKHYQRPASAQPPPPPPP 306
AA E+ SP G APG P PP + + P P P P
Sbjct: 950 ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE---------PGLRGSPGLPGP 1000
Query: 307 AHALQHYLSCG----------GSYPSMGHRA--NLACSPLGGGEPSPG-AGEPSKAGPSG 353
L +CG G G R + SP G+P G AG P +GP G
Sbjct: 1001 ---LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057
Query: 354 ATAGASGRAT----GPEAAGGGGAGGGGGGYRPIIQSPGYKT--GKGGYGAAAGGATRPP 407
R GP+ G G G R PG + G A
Sbjct: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117
Query: 408 PPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP--QGLLGPQAYGQGFGGGQ 465
PP P G G G G+A PG P G+ GPQ QG G
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG-SQGERGAD 1176
Query: 466 AQDLSKAPSYSGGPPQ---PPSGPPPPGL-ATCQSYSPDQLQGQ--------------LY 507
+ K G P PP P PPG + P +QG L
Sbjct: 1177 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 1236
Query: 508 GVQGEP-------YPGPA-----AHSQGLP-----TASPSLSYSTGHS--PALSGHGGGW 548
G+ GE PGP A GLP P TG S P G G
Sbjct: 1237 GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAM 1296
Query: 549 G-------PSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPG---APGKYLSSVLASAP 598
G P G G P P P G P G PG PG+ S +P
Sbjct: 1297 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 1356
Query: 599 ----FLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPR 654
FL P G G G KG G E + G G P + E + I+ P
Sbjct: 1357 GLPGFLGPRGP----PGEPGEKGV-PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411
Query: 655 TSGADGLVGEDGAAD--ASKGLGGSGGAGGPPGTPYE-----LAKEDPQRYHLQSVIRTS 707
G G+ G G +GL G G GPPG P + L E P L+ +I+
Sbjct: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471
Query: 708 ASLDEGATAALELG-----LGRLKEKKKGPERGGETPEGLATSVVHYGA-GAKELGAFLQ 761
A L + + + GP G +GL G G G
Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPP-GPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
Query: 762 KSPPPPPPTAQSTQPTPH----GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSAS 817
S P P + + P GL E G P +P P P L P P
Sbjct: 1531 PSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPG--QPGEPGYAKDGLPGIPGPQGETG 1588
Query: 818 KVGVHLLEPATRDGAPQPPPPP 839
PA G P PP PP
Sbjct: 1589 --------PAGHPGLPGPPGPP 1602
Score = 85.1 bits (209), Expect = 6e-16
Identities = 160/599 (26%), Positives = 195/599 (32%), Gaps = 91/599 (15%)
Query: 125 PGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS 184
PGP+ PG P S L + P R P + + PP P + LLS
Sbjct: 1050 PGPS------GPPGDKGSPGSRGLPGFPGPQGPAGRD-GAPGNPGERGPPGKPGLSSLLS 1102
Query: 185 PHDVLHLK-------PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPP 237
P D+ L P P +P GF+ GV G G + GPP P P
Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFK--GDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160
Query: 238 PRHLPTQFNL--LASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP 295
P Q + + +Q P + F G P PP Q
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220
Query: 296 ASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGAT 355
+ PP P L P + P GEP AGEP GP GA
Sbjct: 1221 PGKEGPPGPQGPSGLP-------GIPGEEGKEGRDGKPGPPGEPGK-AGEPGLPGPEGAR 1272
Query: 356 A--GASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTA 413
G G TG A G G G PG K G G G PP
Sbjct: 1273 GPPGFKGH-TGDSGAPGPRGESGAMGLPGQEGLPG-KDGDTGPTGPQGPQGPRGPPGKNG 1330
Query: 414 TPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA-----------YGQGFG 462
+P GP+ G G+ G+ SPG P G LGP+ +G
Sbjct: 1331 SPGSPGEPGPSG------TPGQKGSKGENGSPGLP-GFLGPRGPPGEPGEKGVPGKEGVP 1383
Query: 463 GGQAQDLSKA----PSYSG--GPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPG 516
G + K P G GPP P PG+ + ++ L G QG P
Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHT------GLMGPQGLPGEN 1437
Query: 517 PAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPA--- 573
G P P G SP++ LG E ++++ Q PPA
Sbjct: 1438 GPVGPPG-PPGQPGFPGLRGESPSMETL-RRLIQEELGKQLETRLAYLL--AQMPPAYMK 1493
Query: 574 --TGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGP 631
GRP G PG PGK P A P G GG +G +GP GP
Sbjct: 1494 SSQGRP---GPPGPPGK------DGLPGRAGPMGEPGRPGQGGLEGP-------SGPIGP 1537
Query: 632 PAER--TEDEEFLIQHLLQAPSPPRTSGADGLVGEDG-AADASKGLGGSGGAGGPPGTP 687
ER D L PP G G GE G A D G+ G G GP G P
Sbjct: 1538 KGERGAKGDPGAPGVGLRGEMGPP---GIPGQPGEPGYAKDGLPGIPGPQGETGPAGHP 1593
Score = 58.2 bits (139), Expect = 8e-08
Identities = 241/1013 (23%), Positives = 302/1013 (29%), Gaps = 234/1013 (23%)
Query: 571 PPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG-KGDGSELLAGPG 629
PP RPP GS +L ++ S P G AG G G KGD + GP
Sbjct: 454 PPPPQRPPTPGSEQIG--FLKTINCSCPAGEKGEMG--VAGPMGLPGPKGDIGAI--GPV 507
Query: 630 GPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYE 689
G P + E + I Q + G+ GL G G D SKG+ G G G PG P E
Sbjct: 508 GAPGPKGEKGDVGIGPFGQGEKGEK--GSLGLPGPPGR-DGSKGMRGEPGELGEPGLPGE 564
Query: 690 LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHY 749
+ PQ L GR+ ERG + G
Sbjct: 565 VGMRGPQ-----------------GPPGLPGPPGRVGAPGLQGERGEKGTRG-------- 599
Query: 750 GAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHA 809
G + L F P P T Q +P P G+ G + V P PP + SV+
Sbjct: 600 EKGERGLDGF----PGKPGDTGQQGRPGPSGVAGPQG--EKGDVGPAGPPGVPGSVVQQE 653
Query: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLR 869
+ P GAP PP P +
Sbjct: 654 GLKGEQGAP------GPRGHQGAPGPPGARGP--------------------------IG 681
Query: 870 PEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPL 929
PE PPG L+ L GD +GPP G G P P G P
Sbjct: 682 PEGRDGPPG--------LQGLRGKKGD--MGPPGIPGL--LGLQGPPGPPGVPGPP---- 725
Query: 930 TSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP-KAGAGPPPGPPAYD 988
G G G G P + G P K G P GPP D
Sbjct: 726 -------------------------GPG-----GSPGLPGEIGFPGKPGPPGPTGPPGKD 755
Query: 989 -PYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPP 1047
P GP P G E GL P KP L + + L +A P P P
Sbjct: 756 GPNGPPGPPGTKGEPGERGEDGL-PGKPG-LRGEIGEQGLAGRPGEKGEAGLPGAPGFPG 813
Query: 1048 PPAPASEP--KGGLTSPIFCSTKPKK----------LLKTSSFHLLRRRDPPFQTPKKLY 1095
+ KG L P + +K L T+S R P Q PK
Sbjct: 814 VRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPK--- 870
Query: 1096 AQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPA-LSPLGDIDFCPPNPGPDGPRR 1154
++ +P + L + RP L P G PG G
Sbjct: 871 -------GEKGDPGLPGEPGL------------QGRPGELGPQGPTG----PPGAKGQEG 907
Query: 1155 RGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAG-PASASTP-TDGAKKPRGRGRGRGRKAE 1212
P A G P G P P P + G P TP DG + +G G
Sbjct: 908 AHGAPGAAGNPGAPGHVGAPG--PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965
Query: 1213 EAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEE 1272
G R +P P +P G G + G+ L L + K++ E
Sbjct: 966 V--GPRGDPGAP-----GLP-GPPGKGKDGEPGLRGSP--GLPGPLGTKAACGKVRGSEN 1015
Query: 1273 KQPE---MKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPP--KSVPPSVPARGLQ-PQP 1326
+K A + + P + AG P PP K P S G PQ
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075
Query: 1327 PA-TPAVPHPP----PSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFS 1381
PA P P P G GL L + L + C L LP F
Sbjct: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP----GLPGLPGFK 1131
Query: 1382 SDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS 1441
D+ P G + GPP +PGPP + G P
Sbjct: 1132 GDK------------------GVPGKPGREGTEGKKGEAGPP-----GLPGPPGIAG-PQ 1167
Query: 1442 ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS---PPPLVAPTPSSPPP 1498
+ + +K P P P P PP + PP + PP
Sbjct: 1168 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 1227
Query: 1499 PPLPPPPPPAMP----------SPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541
P P P +P P PP P A EP P PE P
Sbjct: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA------GEPGLPGPEGARGP 1274
Score = 44.7 bits (104), Expect = 0.001
Identities = 73/284 (25%), Positives = 91/284 (32%), Gaps = 47/284 (16%)
Query: 1314 PPSVPAR-GLQPQPPATPAVPHPP-PSGAFGLGGALEAAESEGLG-----------LGCP 1360
PP +P GLQ PP P VP PP P G+ GL G + G G P
Sbjct: 703 PPGIPGLLGLQG-PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPP 761
Query: 1361 SPCKRLDEELKRNLETLPS---FSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTS 1417
P E +R + LP + + R ++ + A P + G K
Sbjct: 762 GPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 821
Query: 1418 TPDGPPLAPAA-------AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
G P GP PGLP S TP P + P P+ +
Sbjct: 822 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM---------PGEQGPKGE 872
Query: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEP 1530
P P +P L P + P P PP A P AA P
Sbjct: 873 KGDPGLPGEPGLQGRPGELGPQG--------PTGPPGAKGQEGAHGAPGAAGNPGAPGHV 924
Query: 1531 AAPSPEDPELPDTRPLHLAKKQETAAVCGETDEE--AGESGGEG 1572
AP P P P + T GE E+ AGE G G
Sbjct: 925 GAPGPSGPPGSVGAP----GLRGTPGKDGERGEKGAAGEEGSPG 964
Score = 38.5 bits (88), Expect = 0.068
Identities = 22/41 (53%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 1030 IQSGPHQAA----PPPPPPPPPPPAPASEPKGGLTSPIFCS 1066
I SGP Q PPPPPPP PP P SE G L + I CS
Sbjct: 438 IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKT-INCS 477
Score = 36.2 bits (82), Expect = 0.34
Identities = 51/184 (27%), Positives = 62/184 (33%), Gaps = 24/184 (13%)
Query: 1678 GQAKNPVSAGGSSAPPPKAP----APPPKPETPEKTTSEKPPEQTPETAMPEPPAPE--- 1730
G A NP + G AP P P P TP K E P P P
Sbjct: 913 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972
Query: 1731 -KPSLLRPVEKEKEKEKVTRGERPL---RGERATSGRQTRPERSLATGQ--------PAT 1778
P L P K K+ E RG L G +A G+ E GQ P
Sbjct: 973 GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI 1032
Query: 1779 SRLPKAR--PTKVKAEPPPKKRKKWLKEAGGNATAGGGP-PGSSSDSESSPGAPSEDERA 1835
P +R P A PP K + G+ G P P + + +PG P ER
Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPG--ERG 1090
Query: 1836 VPGR 1839
PG+
Sbjct: 1091 PPGK 1094
Score = 31.6 bits (70), Expect = 8.3
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 1459 PTPPPAPTPQPQPPPPPPPPQPALP 1483
P+ P T +PPPPPPP +P P
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTP 463
Score = 31.6 bits (70), Expect = 8.3
Identities = 51/178 (28%), Positives = 59/178 (33%), Gaps = 24/178 (13%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P G P GGS P + P KP P T PP + P PP
Sbjct: 715 PPGPPGVPG----PPGPGGSPGLPGEIGFPG-KPGPPGPTG---PPGKDGPNGPPGPPGT 766
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTK- 1788
+ E + E G+ LRGE G RP G P P R K
Sbjct: 767 KG-------EPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819
Query: 1789 ---VKAEPPPKKRKKWLKEAGGNATAG-GGPPGSSSDSESSPGAPSED----ERAVPG 1838
K E K E G AG G PG++S P P E E+ PG
Sbjct: 820 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 877
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 115 bits (289), Expect = 3e-25
Identities = 247/926 (26%), Positives = 299/926 (32%), Gaps = 143/926 (15%)
Query: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTP--PYRPGPPDPPPPPRHLPTQFN---- 246
P+ P P ++G G V P GP P P G P PP LP +F
Sbjct: 476 PAGLPGPPGTMG----PTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD 531
Query: 247 -------LLASSSAAAAAAEQSSPQLYNFSG-----AAPGP--PPPERALPRQDTVIKHY 292
+ A S A A +Q+ L +G PGP PP L + +
Sbjct: 532 AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP- 590
Query: 293 QRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA----GEPSK 348
Q P Q PP P + G+ G G PG G+P
Sbjct: 591 QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650
Query: 349 AGPSGATAGASGRA----TGPEAAGG--GGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGG 402
+GP G R GP G G G G P P TG G G
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710
Query: 403 AT---RPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQ 459
P PP P Q L GP A G G G+ PG P G GP
Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIG---PPGEKGPLGKPGLPGMP-GADGP----P 762
Query: 460 GFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAA 519
G G + K GP P P P G+ D ++G L G +GE
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVK-----GADGIRG-LKGTKGE------K 810
Query: 520 HSQGLPTASPSLSYSTGHS----PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATG 575
G P + P G G GP GG P+ PL P G
Sbjct: 811 GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG-----PNGDPGPLGPPGEKG 865
Query: 576 RPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAER 635
+ G PG PG+ S F PGA G G GK G GP GP ER
Sbjct: 866 KLGVPGLPGYPGR--QGPKGSIGFPGFPGANG-EKGGRGTPGK-PGPRGQRGPTGPRGER 921
Query: 636 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDG--AADASKGLGGSGGAGGPPGTPYE--LA 691
+ + P P SG DG G G + +G G G GPPG P + L
Sbjct: 922 GP------RGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975
Query: 692 KEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGA 751
QR +T G G E ERG P G G
Sbjct: 976 GHPGQRGETGFQGKTGPPGPPGVVGP----QGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031
Query: 752 GAKELGAFLQKSPPPPP----PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLS 807
KE G P P P P GL G L PP P
Sbjct: 1032 AGKE-GTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP-------- 1082
Query: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPR 867
P P+ S + G PA G P P P PP P + G P P+ R
Sbjct: 1083 --PGPAGSPGERG-----PAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG--PQGPAGR 1133
Query: 868 LRPEESLDPPGAMQELLGALEPLPPAPGDTG-VGPPNSEG-KDPAGAYRSPSPQGTKAPR 925
+ L P + G + P P GD G +G P +G K G P P G + P
Sbjct: 1134 ----DGLQGPVGLPGPAGPVGP-PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPI 1188
Query: 926 FVPLTSICFPDSLLQDEERSFFPTMEEMFGG-----GAADDYGKAGPPEDEGDP-KAGAG 979
P S + + ++ F +E G G G GPP ++G+ G
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248
Query: 980 PPPGPPAYDPYGPYCPGRASGA-GPETPGLGL----------------DPNKPPE-LPST 1021
PPGPP GP P A GA GP+ P G+ +P P E P
Sbjct: 1249 GPPGPP-----GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1303
Query: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPP 1047
E +SGP AA PP P PP
Sbjct: 1304 PKGERGEKGESGPSGAAGPPGPKGPP 1329
Score = 110 bits (276), Expect = 1e-23
Identities = 252/998 (25%), Positives = 316/998 (31%), Gaps = 167/998 (16%)
Query: 125 PGPTELFISGALPGSSTFPSSSALSAYQHP-ASFGSRPFPVPSSLSLQDPPFSPPANGLL 183
PGP L PG P + + P + G + P P +P A GL
Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQ-----GNPGAQGLP 732
Query: 184 SPHDVLHLKPSQAPTVPSSLGFERLAG-GGVLGPAGLGPAQTPPYRPGPPDPPPP----- 237
P + + P LG L G G GP G + PP G PP P
Sbjct: 733 GPQGAIGPPGEKGP-----LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787
Query: 238 ---PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAP-----GPPPPERALPRQDTVI 289
PR + + E P G GPP P +
Sbjct: 788 YPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP-- 845
Query: 290 KHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS-MGHRANLACSPLGGGEPSPGA-GEPS 347
K P + P P PP + + YP G + ++ G G G P
Sbjct: 846 KGRGGP-NGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPG 904
Query: 348 KAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP 407
K GP G TGP G G R I PG K GG G A R P
Sbjct: 905 KPGPRGQRG-----PTGPR---------GERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950
Query: 408 --PPRSTATPKCQSLGGPAAAYAT-GKASGAGGAGGQAYS-PGQPQGLLGPQAYGQGFGG 463
P T P + GP G G G Q + P P G++GPQ G
Sbjct: 951 NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQ-------G 1003
Query: 464 GQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEP----YPGPAA 519
+ GPP PP PGLA + D L G G P +PG
Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG--- 1060
Query: 520 HSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGG-GEASPSHIIRPLQSP--PATGR 576
+GLP +L L G+ G GP G GE P+ P+ P P
Sbjct: 1061 -DRGLPGPVGALG--------LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQG 1111
Query: 577 PPG-VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAER 635
PPG G GAPG+ A L P AG G G+ + PG ++
Sbjct: 1112 PPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKG 1171
Query: 636 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADAS--------KGLGGSGGAGGPPGTP 687
+ E+ PP +G G +G+ G + A +GL G G GP G P
Sbjct: 1172 DKGEQ----------GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP 1221
Query: 688 YELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVV 747
P LQ + E G + G + P+G +
Sbjct: 1222 -----GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276
Query: 748 HYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLS 807
+ GA E G + P P + P P G E G PP P+ P
Sbjct: 1277 NPGA-VGEKGEPGEAGEPGLP--GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPG--D 1331
Query: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPP-----PPPPM-----PLQLEAHLRSH 857
P SP P G P PP P P PP P Q + +
Sbjct: 1332 DGPKGSPG----------PVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTG 1381
Query: 858 GLEPAAPSPRLRPEESLDPPGAMQELLGALEP-LPPAPGDTG-VGPPNSEGKDPAGAYR- 914
P+ P + P P G E E L PG TG +GP + GK R
Sbjct: 1382 EPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRG 1441
Query: 915 ------------SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDY 962
SP P G P P DS + E+ G
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK-------------GHPGLI 1488
Query: 963 GKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTV 1022
G GPP ++G+ G PGP GP G GP P + P PP LP
Sbjct: 1489 GLIGPPGEQGEK--GDRGLPGPQGSS--GP--KGEQGITGPSGP---IGPPGPPGLPGPP 1539
Query: 1023 NAEPLGLI-QSGPH----QAAPPPPPPPPPPPAPASEP 1055
P G SGP +A P PP PP PP +P
Sbjct: 1540 G--PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575
Score = 108 bits (271), Expect = 4e-23
Identities = 201/753 (26%), Positives = 240/753 (31%), Gaps = 144/753 (19%)
Query: 210 GGGVLGPAG-LGP--AQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLY 266
G G GP G GP Q P PGP PP PP ++
Sbjct: 938 GDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP----------GKDGLPGHPGQRGET--- 984
Query: 267 NFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHR 326
F G GPP P + Q + P PP PP P + +
Sbjct: 985 GFQGKT-GPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ---------GLPGLAGK 1034
Query: 327 ANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQS 386
G+P P AG P K GP G G G P G G G G P
Sbjct: 1035 EGTK------GDPGP-AGLPGKDGPPGLR-GFPGDRGLPGPVGALGLKGNEGPPGP--PG 1084
Query: 387 PGYKTGKGGYGAAAG--GATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYS 444
P G+ G AAG G P P+ P + G P G A G G G
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK-GAPGEKGPQGPA-GRDGLQGPVGL 1142
Query: 445 PGQPQGLLGPQAYGQGFG--GGQAQDLSKAPSYSGGPPQP--PSGP-PPPGLATCQSYSP 499
PG P G +GP G G Q SK GPP P P GP PG +
Sbjct: 1143 PG-PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201
Query: 500 DQLQGQLYGVQGEP----YPGPAAHS--QGLPTASPSLSYSTGHSPALSGHG--GGWGPS 551
+ Q L+G +G+ +PGP QGLP P TG + G G GPS
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLP-GPPGEKGETGDVGQMGPPGPPGPRGPS 1260
Query: 552 SLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAG 611
G G P G P G+G+PGA G+ A P L G G
Sbjct: 1261 --GAPGADGPQ------------GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306
Query: 612 AGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG----- 666
G KG+ G AGP GP +D + P P G G G+DG
Sbjct: 1307 ERGEKGE-SGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDK 1365
Query: 667 AADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLK 726
D G GS G G PG K P A E GR
Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPP-----------------GPAGPE---GRQG 1405
Query: 727 EKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG 786
EK E G E P G + GA K L+ P P P P G G
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMG 1465
Query: 787 GPDLP-------------------LVLPP-----------PPPQ-----------LLPSV 805
P LP L+ PP P PQ PS
Sbjct: 1466 PPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG 1525
Query: 806 LSHAPS-------PSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM-PLQLEAHLRSH 857
P P P +K P G P PP PP PP + PL ++A
Sbjct: 1526 PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRR 1585
Query: 858 GLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890
++ + E +D M+E+ G+L L
Sbjct: 1586 NIDASQLLDDGNGENYVDYADGMEEIFGSLNSL 1618
Score = 106 bits (264), Expect = 3e-22
Identities = 391/1672 (23%), Positives = 509/1672 (30%), Gaps = 394/1672 (23%)
Query: 115 SPSWQTAM------HTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSL 168
SP TA+ P P E + G G + + Y+ P G P P +
Sbjct: 241 SPDCDTAVPDTPQSQDPNPDEYYTEGDGEGETYYYE---YPYYEDPEDLGKEPTPSKKPV 297
Query: 169 SLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPP-- 226
P L+P P++A +P E G G G+G P
Sbjct: 298 EAAKETTEVPEE--LTP------TPTEAAPMP-----ETSEGAGKEEDVGIGDYDYVPSE 344
Query: 227 --YRPGP------------PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAA 272
Y P P PD P P A AE + + +
Sbjct: 345 DYYTPSPYDDLTYGEGEENPDQPTDP----------------GAGAEIPTSTADTSNSSN 388
Query: 273 PGPPPPERALPRQDTVIK-------------HYQRPASAQPPPPPPPAHALQHYLSCGGS 319
P PPP E A + + +Y +S P PA+ Y GG
Sbjct: 389 PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGP 448
Query: 320 YPSMGHRANLAC--------SPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGG 371
G + A P G P+ G P GP+G G G P G
Sbjct: 449 RGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQV-GDPGERGPPGRPGLP 507
Query: 372 GAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG--GPAAAYAT 429
GA G G ++ P ++ G GG + G ++ A + L GPA
Sbjct: 508 GADGLPGPPGTMLMLP-FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL 566
Query: 430 GKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPP 489
G G G G+P G +GPQ P GPP P P
Sbjct: 567 TGRPGPVGPPGSGGLKGEP-GDVGPQG----------------PRGVQGPPGPAGKPGRR 609
Query: 490 GLATCQSYSPDQLQGQLYGVQGEP-------YPGPAAHSQGLPTASPSLSYSTGHSPALS 542
G A S + GQ G +G+ PG H +G P PS
Sbjct: 610 GRAG--SDGARGMPGQT-GPKGDRGFDGLAGLPGEKGH-RGDP--GPSGPPGPPGDDGER 663
Query: 543 GHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV----GSPGAPGKYLSSVLASAP 598
G G GP L G E P ++ P + PP PPGV G PG G
Sbjct: 664 GDDGEVGPRGLPG--EPGPRGLLGP-KGPPGPPGPPGVTGMDGQPGPKGN---------- 710
Query: 599 FLAPPGAGSYAAGAGGYKGKGDGSELLAGPGG---PPAERTEDEEFLIQHLLQAPSPPRT 655
+ P G G G +G G++ L GP G PP E+ L P P
Sbjct: 711 -VGPQGE----PGPPGQQGN-PGAQGLPGPQGAIGPPGEKGP---------LGKPGLPGM 755
Query: 656 SGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGAT 715
GADG G G +G G G GPPG + P+ +GA
Sbjct: 756 PGADGPPGHPG----KEGPPGEKGGQGPPGPQGPIGYPGPRGV-------------KGAD 798
Query: 716 AALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQ 775
G+ LK K E+G + G + G E+G PP P +
Sbjct: 799 -----GIRGLKGTKG--EKGEDGFPGFKGDMGIKGDRG-EIG--------PPGPRGEDGP 842
Query: 776 PTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQP 835
P G G P PL P +L L P +G A + +
Sbjct: 843 EGPKGRGGPNGDPG-PLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG 901
Query: 836 PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPG 895
P P P P P P PG P + G
Sbjct: 902 TPGKPGPRGQRG-------------PTGPRGERGPRGITGKPG----------PKGNSGG 938
Query: 896 DTGVGPPNSEGKD-PAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMF 954
D GPP G + P G P P+G P P Q E F
Sbjct: 939 DGPAGPPGERGPNGPQGPTGFPGPKGPPGPP----GKDGLPGHPGQRGETGF-------- 986
Query: 955 GGGAADDYGKAGPPEDEG-----DPKAGAGP--------PPGPPAYDPYGPYCPGRASGA 1001
GK GPP G P GP PPGPP PG A
Sbjct: 987 -------QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL----PGLAGKE 1035
Query: 1002 GPE-TPGLGLDPNK--PPELPSTVNAEPL-GLIQSGPHQAAPPPPPPPPPPPAPASEPKG 1057
G + PG P K PP L L G + + + PP PP P +P
Sbjct: 1036 GTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPA 1095
Query: 1058 GLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLN 1117
G PI +P + PP +K E + + D
Sbjct: 1096 GAAGPIGIPGRPGP------------QGPPGPAGEKGAPGEKGPQGPAGR-----DGLQG 1138
Query: 1118 PRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDG-------PRRRGRKPTKAKRDGPPRP 1170
P LP PA P+G PG DG P ++G K K ++ GPP P
Sbjct: 1139 PVGLPG--------PA-GPVGP-------PGEDGDKGEIGEPGQKGSKGDKGEQ-GPPGP 1181
Query: 1171 RGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIK-L 1229
G P+ P GP+ A DG PRG+ G+K +E P P+ ++ L
Sbjct: 1182 TGPQG--PIGQP---GPSGA----DGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232
Query: 1230 SVPKAGEG-------------------LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEV 1270
P +G G D G + EK E E
Sbjct: 1233 PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG--EA 1290
Query: 1271 EEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP 1330
E + G + + G+ P AG P PP P P P P
Sbjct: 1291 GEPGLPGEGGPPGPKGERGEKGESGPS-GAAGPPGPKGPPGDDGPKG-----SPGPVGFP 1344
Query: 1331 AVPHPP----PSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEED 1386
P PP P+G G G + + E G P P P + E
Sbjct: 1345 GDPGPPGEPGPAGQDGPPGD-KGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGR 1403
Query: 1387 SVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS-ANSN 1445
K A + L GP + P GP AP PGP L G+P
Sbjct: 1404 QGEKG------------AKGEAGLEGPPGKTGPIGPQGAPGK--PGPDGLRGIPGPVGEQ 1449
Query: 1446 GTPEPPLLEEKPPPTPPPA-------PTPQPQPPPP-------PPPPQP-----ALPSPP 1486
G P P + P P PP P+ + P PP Q LP P
Sbjct: 1450 GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1509
Query: 1487 PLVAPT-------------PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533
P P PP P PP P A S P P A PP P P
Sbjct: 1510 GSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569
Query: 1534 SPEDPELPDTRPLHLAKKQETAAVCGETDEEAGES------GGEGIFRERDEFVIRAEDI 1587
E+ P+ ++ + D+ GE+ G E IF + + +I
Sbjct: 1570 G----EVIQPLPIQASRTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLKL---EI 1622
Query: 1588 PSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ-----RQFCATSNYLGY 1634
+K L T + P + LQ P+ DG+ Q C+ ++ Y
Sbjct: 1623 EQMKRPLGTQQNPARTCKD----LQLCHPDFPDGEYWVDPNQGCSRDSFKVY 1670
Score = 50.4 bits (119), Expect = 2e-05
Identities = 109/463 (23%), Positives = 148/463 (31%), Gaps = 79/463 (17%)
Query: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLL-----EEKPPPTPP 1462
P LAG + T GP P GPP L G P G P P E PP P
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGK--DGPPGLRGFPG--DRGLPGPVGALGLKGNEGPPGPPG 1084
Query: 1463 PAPTPQPQPP-----PPPPPPQPALPSPPPLV----APTPSSPPPPP----LPPP---PP 1506
PA +P + P P P +P PP AP P P L P P
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPG 1144
Query: 1507 PAMPSPPPPPPPAAAPLAAPPE--------EPAAPSPEDPELPDTRPLHLAKKQETAAVC 1558
PA P PP + P + E P P P+ P +P
Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG--------- 1195
Query: 1559 GETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEI 1618
D E G G +G+F ++ + R P + LQ G PP + + + + P
Sbjct: 1196 --ADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQ-GLPGPPGEKGETGDVGQMGPPG 1252
Query: 1619 KDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSG 1678
G R G G V + + PP P G
Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG---PPGPKGERG 1309
Query: 1679 QAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPV 1738
+ +G + P PK PP + P+ + P P PP P+
Sbjct: 1310 EKGESGPSGAAGPPGPKG---PPGDDGPKGS-----PGPVGFPGDPGPPGEPGPA----- 1356
Query: 1739 EKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKR 1798
G+ G++ G + TG+P S P R A P ++
Sbjct: 1357 -----------GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405
Query: 1799 KKWLKEAGGNATAGGGPPGSSS--DSESSPGAPSEDE-RAVPG 1838
+K K G GPPG + + +PG P D R +PG
Sbjct: 1406 EKGAKGEAGLE----GPPGKTGPIGPQGAPGKPGPDGLRGIPG 1444
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 115 bits (287), Expect = 6e-25
Identities = 121/430 (28%), Positives = 158/430 (36%), Gaps = 53/430 (12%)
Query: 1159 PTKAKRDGP-----PRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG-RGRGRKAE 1212
P A R GP P GR P T+ GP S+ G +P G +G AE
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 1213 EAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNS----LDSSLTREKIEAKIK 1268
E P + LS + G + G S + L R A+ +
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 1269 E-VEEKQPEMKSGFMASFLDFLKSGKRHPPL-----------YQAGLTPPLSPPKSVP-- 1314
E + + S S + + +R P + TP SP +S P
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 1315 ---PSVPARGLQPQPPATPAVPHP----PPSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
P PA QP+P A+ P P A G L ++ L PSP
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-----LATPSPSAPPS 305
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
+L+TLPS + + ++ + S L PPL+ P T P PP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFLPSPPLS-PLATPPPQAPPALAL 363
Query: 1428 AAVPGPPPLPGLPSANSNGTPEPP--------LLEE--KPPPTPP-PAPTPQPQPPPPPP 1476
+ PP P P + TP P LL+ PPP+PP AP P PP P
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423
Query: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536
P +PP L AP PP PP PP P+ PP PP PLAAPP + A P P+
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP----PLAAPPLQLAKPPPQ 479
Query: 1537 DPELPDTRPL 1546
P T PL
Sbjct: 480 APPALATPPL 489
Score = 108 bits (271), Expect = 4e-23
Identities = 123/449 (27%), Positives = 167/449 (37%), Gaps = 76/449 (16%)
Query: 1131 RPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRP-LEVP----TTA 1185
R ALS D P PG P R G PRP R RP E P ++A
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203
Query: 1186 GPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGL-GTSSGD 1244
S + P+ A++ G G R A + + PL S ++G GT
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS------SPARSGPSARGTPRAP 257
Query: 1245 AISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLT 1304
A +L ++ K+ + S +A+ PP Q +
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317
Query: 1305 PPLSPPKSVPPSVPARGLQ------PQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLG 1358
PP +PP S+ + LQ P PP +P PPP L AL ++
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-PPPQAPPAL--ALPPLQAP----- 369
Query: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418
PSP L L + S +++A + + + S PP+ P S
Sbjct: 370 -PSP------PASPPLSPLATPSPQAPNALAVHL-----LQAPFSPPPSPPVQAP--FSP 415
Query: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP------PAPTPQPQPP 1472
P PP++P+A P P P L + PPL + PP+PP P+ TP PQ P
Sbjct: 416 PASPPVSPSATPPSQAP-PSLAA--------PPL---QVPPSPPASPPMSPSATPPPQAP 463
Query: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP------------------PPAMPSPPP 1514
PP P L PPP P ++PP LP PP P A P P
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 523
Query: 1515 PPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543
PP AA L PP PA+P+ + P P T
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPT 552
Score = 100 bits (250), Expect = 1e-20
Identities = 157/619 (25%), Positives = 214/619 (34%), Gaps = 116/619 (18%)
Query: 970 DEGDPKAGAGPPPGPPAYDPYGPYCPGRASGA-GPETPGLGLDPNKPPELPST------- 1021
D KA AG PA RA G P PG P PP P+
Sbjct: 2 DNKRDKAKAGAAARTPA---------ARAPGLLTPRPPGSPRPP--PPVTPAALRVLGAA 50
Query: 1022 --VNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGL--TSPIFCSTKPKKLLKTSS 1077
V +PL G A P P P + P G +P +T P +
Sbjct: 51 GAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGR 110
Query: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRR--------LPDLVSSCR 1129
R P Q ++ A+E +A + + RR P + R
Sbjct: 111 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 170
Query: 1130 SRPALSPLGDIDFCP---PNPGPDGPRRR--------GRKPTKAKRDGPPRPRG--RPRI 1176
SR A + +G P P P +GPR+ +P+ A R P G RP
Sbjct: 171 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230
Query: 1177 R-------PLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKL 1229
R PL P +GP++ TP A + + +G L+ L+P ++
Sbjct: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG------------LQALRPPQVTP 278
Query: 1230 SVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFL 1289
A LG S ++ ++ S ++ + + + L
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 1290 KSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATP-----AVPHPPPSGAFGLG 1344
S PPL PP +PP P + A P PPA+P A P P A +
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQA---PPSPPASPPLSPLATPSPQAPNALAVH 395
Query: 1345 GALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA 1404
L+A S PSP + + PS + S A +
Sbjct: 396 -LLQAPFSPP-----PSPPVQAPFSPPASPPVSPSATPP---------------SQAPPS 434
Query: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVP--GPPPLPGLPSANSNGTPEPPLLEEKPPP-TP 1461
L PPL P S P PP++P+A P PPPL PPL KPPP P
Sbjct: 435 LAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAA-----------PPLQLAKPPPQAP 481
Query: 1462 PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP--PPAMPSP--PPPPP 1517
P TP Q P PP + P P +P+ S P P PPP PP + +P PP
Sbjct: 482 PALATPPLQALPSPP---ASFPGQAPF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537
Query: 1518 PAAAPLAAPPEEPAAPSPE 1536
P A+P P P P P+
Sbjct: 538 PPASPTLQAPRRPPTPGPD 556
Score = 99.0 bits (245), Expect = 4e-20
Identities = 188/707 (26%), Positives = 239/707 (33%), Gaps = 153/707 (21%)
Query: 517 PAAHSQGLPTASPSLSYS-----TGHSPALSGHGGGWGPSSL-----GGGGEASPSHIIR 566
PAA + GL T P S T + + G G G L G GG P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA-- 74
Query: 567 PLQSPPATGRPP--GVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSEL 624
P P T RPP G G P K S S+P A +G+ G G KG +E
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTRPGPLGQKGLRISAEE 131
Query: 625 LAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPP 684
G + TE + + L A + TSG A S+ G G P
Sbjct: 132 TVARG----KATEAPK---RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 685 GTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLAT 744
+ + R + S S + E + AA ++ P GG +
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTT--EPSPAA-----------RRRPSAGGGLQRPASR 231
Query: 745 SVVHYGAGAKELGAFLQKSPPP---PPPTAQSTQPTPHGLLLEAGGPDLPLVLPP---PP 798
S+ + A L + + P P A +QP P GL +A P P V PP
Sbjct: 232 SL---SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL--QALRP--PQVTPPRKDAA 284
Query: 799 PQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP-----PPPPPPMPLQLEAH 853
P L P S +PSPSA P P PP P PP P Q
Sbjct: 285 PALGPLSSSPLATPSPSAP---------------PSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 854 LRSHGLEPA---APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPA 910
L S L+ PSP L P + PP A L AL PL PP+ P
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLAT-PPPQAPPAL--ALPPLQ--------APPSPPASPPL 378
Query: 911 GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPED 970
+PSPQ AP + + + P S P ++ F A+ + P
Sbjct: 379 SPLATPSPQ---APNALAVHLLQAPFSPPPS------PPVQAPFSPPASPPVSPSATPPS 429
Query: 971 EGDPKAGAGP---PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027
+ P A P PP PPA P P TP PP+ P + A PL
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSA----------TP--------PPQAPPPLAAPPL 471
Query: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087
L + PPP PPA A+ P L SP ++S + PP
Sbjct: 472 QLAK-----------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520
Query: 1088 FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP 1147
Q P L A + VP P SP PP P
Sbjct: 521 PQAPPVLAAPLLQ---------VPPS------------------PPASPTLQAPRRPPTP 553
Query: 1148 GPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPT 1194
GPD G + T A GPP P R L P AG +S++T T
Sbjct: 554 GPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599
Score = 97.1 bits (240), Expect = 2e-19
Identities = 184/773 (23%), Positives = 247/773 (31%), Gaps = 195/773 (25%)
Query: 817 SKVGVHLLEPATRDGA---PQPPPPPPPPPP--PMPLQLEAHLRSHGLEPAA-------- 863
+K G PA R P+PP P PPPP P L++ + G +P A
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 864 -----PSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSP 918
+PR P + PP + G E PPA +T GP +S G+ A P P
Sbjct: 68 ATIPESAPRAGPTRTSRPPAS-----GRGERAPPAK-NTSPGPVSSPGR--ASGTTRPGP 119
Query: 919 QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGA 978
G K R + EE G A + K G + +
Sbjct: 120 LGQKGLRI----------------------SAEETVARGKATEAPKRS-ALSAGARRDTS 156
Query: 979 GPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAA 1038
GP PG P+ P R+ AG E +GL P P P + S +
Sbjct: 157 GPTPGTPS-----PAMARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSASEHST 208
Query: 1039 PPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQE 1098
P P P+ GGL P + L +S+ P +P +
Sbjct: 209 TEPSPAARRRPSAG----GGLQRP------ASRSLSSSA--------TPLSSPARSGPSA 250
Query: 1099 YEFEADEDKADVPADIRLNPRRLPDLVSSCR-SRPALSPLGDIDFCPPNPGPDGPRRRGR 1157
P L R P + + + PAL PL P+P
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP---------- 300
Query: 1158 KPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGT 1217
PP P P ++ L P P+ A+T G +A +
Sbjct: 301 -------SAPPSPSAPPSLQTLPSPPATPPSQATT-------------SLGSPTLQATHS 340
Query: 1218 RL--EPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQP 1275
L PL PL P+A L A + + P
Sbjct: 341 FLPSPPLSPL--ATPPPQAPPALALPPLQAPPS------------PPASPPLSPLATPSP 386
Query: 1276 EMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKS--------VPPSVPARGLQ--PQ 1325
+ + L S PP+ QA +PP SPP S PPS+ A LQ P
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445
Query: 1326 PPATPAV---PHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSS 1382
PPA+P + PPP A + L L P P + L T P
Sbjct: 446 PPASPPMSPSATPPPQ-------APPPLAAPPLQLAKPPP------QAPPALATPP---- 488
Query: 1383 DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSA 1442
+ AL PP S P P +P+A++P P P A
Sbjct: 489 -------------------LQALPSPP------ASFPGQAPFSPSASLPMSPLATPPPQA 523
Query: 1443 NSNGTPEPPLLEE---KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
PP+L + PP+PP +PT Q PP P P ++ P +A P PPPP
Sbjct: 524 -------PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576
Query: 1500 PLPPPPPPAMP-------SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
P + P S P + P AA P D EL P
Sbjct: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 629
Score = 96.3 bits (238), Expect = 3e-19
Identities = 180/735 (24%), Positives = 252/735 (34%), Gaps = 141/735 (19%)
Query: 33 GSSRTSHPETDILHRQAYAA----PHPLQSYA-----TNHHPAGLSGLF----DTGLHHA 79
G +RTS P +A A P P+ S T P G GL +T
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 80 GSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPT----------E 129
+ P S ++ + ++ GP PG + ++ + R+ + + P P+
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 130 LFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVL 189
+S A S+T PS +A + P++ G P SLS P S PA P
Sbjct: 198 KSVSSASEHSTTEPSP---AARRRPSAGGGLQRPASRSLSSSATPLSSPARS--GPSARG 252
Query: 190 HLKPSQAPTVPSSLGFERLAGGGVLGP-----AGLGPAQTPPYRPGPPDPPPPPRHLPTQ 244
+ P+ P G + L V P LGP + P P PP P P+
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 245 FNLLASSSAAAAAAEQS--SPQLYNFSGAAPGPP------PPERALPRQDTVIKHYQRPA 296
L + + + A S SP L P PP PP +A P + Q P
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA--LALPPLQAPP 370
Query: 297 S--AQPP------PPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSK 348
S A PP P P +AL +L P SP SP A PS+
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430
Query: 349 AGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPP 408
A PS A + P + + P + +P + K PPP
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK------------PPP 478
Query: 409 --PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA-------YGQ 459
P + ATP Q+L P A++ G A P P PQA Q
Sbjct: 479 QAPPALATPPLQALPSPPASF-----PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 460 GFGGGQAQDLSKAP----------SYSG---------GPPQPP--------SGPPPPGLA 492
A +AP S SG GPP PP SGP G +
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593
Query: 493 TCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGG-----G 547
+ + +P++L+G G +G P ++ L P+ ++S G +P L+ G
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAE-LAACHPA-AWSRGPAPPLAFRGAPGAPLP 651
Query: 548 WGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGS 607
W P++ G G A I + P + PG PG PG
Sbjct: 652 WPPAT--GPGSADGLCTIYETEGPESATPAPGALDPG----------------PSPGTSG 693
Query: 608 YAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA 667
A AG G S A G P + ++QHLL + A+G G G
Sbjct: 694 GKAAAGAGAGASSRSPKQARLGELPLGALQAS--VVQHLLSRTL--LLAAAEGAAGGSG- 748
Query: 668 ADASKGLGGSGGAGG 682
GG GGA G
Sbjct: 749 -------GGPGGAEG 756
Score = 89.0 bits (219), Expect = 4e-17
Identities = 196/818 (23%), Positives = 252/818 (30%), Gaps = 179/818 (21%)
Query: 193 PSQAPTV-PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASS 251
P AP P+ +G G P + P PG P L + +++
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 252 SAAAAAAEQSSPQLY--------NFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPP 303
A +P+ + SG PG P P A R P A P
Sbjct: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-RSRAAGTEVGLPRPAPSARP 189
Query: 304 PPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAG---EPSKAGPSGATAGASG 360
PP + +S S + SP PS G G S++ S AT +S
Sbjct: 190 RPPTEGPRKSVS------SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 361 RATGPEAAGGGGAGG--------GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPP----P 408
+GP A G A G RP +P K G + P P
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 409 PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQD 468
P +A P Q+L P A + + G QA P L P A QA
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP----QAPP 359
Query: 469 LSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTAS 528
P PP PP+ PP LAT +P+ L L P P P + P AS
Sbjct: 360 ALALPPLQA-PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 529 PSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGK 588
P +S S +P PS +A PS PLQ PP+ P + P
Sbjct: 419 PPVSPSA--TP----------PS------QAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 589 YLSSVLASAPF-LAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLL 647
LA+ P LA P P PPA T + L
Sbjct: 461 QAPPPLAAPPLQLAKP-----------------------PPQAPPALATPPLQAL----- 492
Query: 648 QAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTS 707
PSPP + S L S A PP P LA +++
Sbjct: 493 --PSPPASFPG------QAPFSPSASLPMSPLATPPPQAPPVLA---------APLLQVP 535
Query: 708 ASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP 767
S T L+ ++ P G +T L L PPPP
Sbjct: 536 PSPPASPT---------LQAPRRPPTPGPDT-----------SVSGPRLTLALAPGPPPP 575
Query: 768 PPT--------------AQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLL----PSVLSHA 809
P + S TP L GP+ PPP L P+ S
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 810 PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ-LEAHLRSHGLEPAAPSPRL 868
P+P P GAP P P PP P L + G E A P+P
Sbjct: 636 PAP-------------PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP-- 680
Query: 869 RPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928
GAL+P P+PG +G GK AGA S + K R
Sbjct: 681 ----------------GALDP-GPSPGTSG-------GKAAAGAGAGASSRSPKQARLGE 716
Query: 929 LTSICFPDSLLQD-EERSFFPTMEEMFGGGAADDYGKA 965
L S++Q R+ E GG+ G A
Sbjct: 717 LPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 754
Score = 83.6 bits (205), Expect = 2e-15
Identities = 192/746 (25%), Positives = 249/746 (33%), Gaps = 147/746 (19%)
Query: 333 PLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTG 392
P G P P P+ GA AGA GR E AGG G G +P
Sbjct: 29 PPGSPRPPPPV-TPAALRVLGA-AGAVGRKPLAERAGGIG------GATIPESAPRAGPT 80
Query: 393 KGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLL 452
+ A+G R PP ++T+ P + G+ASG G P G
Sbjct: 81 RTSRPPASGRGERAPPAKNTS---------PGPVSSPGRASGTTRPG--------PLGQK 123
Query: 453 GPQAYGQG-FGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511
G + + G+A + K + S G + SGP P G + + G G+
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL-- 180
Query: 512 EPYPGPAAHSQGLPTASP--SLSYSTGHSPALSGHGGGWGPSSLGG---GGEASPSHIIR 566
P P P+A + PT P S+S ++ HS PS+ GG S S
Sbjct: 181 -PRPAPSARPRP-PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 567 PLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLA 626
PL SP +G P G+P AP L PP A G S L
Sbjct: 239 PLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297
Query: 627 -------GPGGPPAERT----------EDEEFLIQHLLQA-----PSPPRTSGADGLVGE 664
P PP+ +T + L LQA PSPP + L
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP----LATP 353
Query: 665 DGAADASKGLGGSGGAGGPPGTP--YELAKEDPQRYHLQSVIRTSASLDEGATAALELGL 722
A + L PP +P LA PQ + +V A + ++
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413
Query: 723 GRLKEKKKGPERG--GETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHG 780
P + P LA + + SPP PP + S P P
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQ-----------VPPSPPASPPMSPSATPPPQA 462
Query: 781 LLLEAGGPDL---PLVLPPPPPQLLPSVLSHAPS--PSPSASKVGVHLLEPATRDGAPQP 835
P L PL L PPPQ P++ + PSP AS G P+
Sbjct: 463 ------PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 836 PPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPG 895
PPP PP + L S P +PR P D + L AL P PP
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--- 573
Query: 896 DTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFG 955
PP S RSPS +++ PD L S T EE+ G
Sbjct: 574 -----PPPS---------RSPS------------STLSGPD--LAGHSSSATSTPEELRG 605
Query: 956 GGAADDYGKAGPPEDEGDPKA--------GAGPP------PGPPAYDPYGPYC-PGRASG 1000
+ + G A P + + A G PP PG P P+ P PG A G
Sbjct: 606 YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL--PWPPATGPGSADG 663
Query: 1001 -------AGPE--TPGLG-LDPNKPP 1016
GPE TP G LDP P
Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSP 689
Score = 77.4 bits (189), Expect = 1e-13
Identities = 178/746 (23%), Positives = 230/746 (30%), Gaps = 176/746 (23%)
Query: 948 PTMEEMFGGGAA---DDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYC-PGRASGAGP 1003
P E G G A + +AGP P +G G P GP PGRASG
Sbjct: 57 PLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 116
Query: 1004 ETP----GLGLDPNKPPELPSTVNAEPLGLIQSGPHQ-AAPPPPPPPPPPPAPASEPKG- 1057
P GL + + A + +G + + P P P P A S G
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 1058 --GLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR 1115
GL P S +P+ PP + P+K + E E PA
Sbjct: 177 EVGLPRPA-PSARPR---------------PPTEGPRKSVSSASEHSTTEPS---PA--- 214
Query: 1116 LNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRK-----PTKAKRDG---- 1166
RR P + RPA L +P GP RG P++ K G
Sbjct: 215 --ARRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 1167 ------PPRPRGRPRIRPLE-----VPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAG 1215
PPR P + PL P+ + P S S P P + G
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331
Query: 1216 GTRLE---------PLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAK 1266
L+ PL PL P+A L A + S L
Sbjct: 332 SPTLQATHSFLPSPPLSPLATP--PPQAPPALALPPLQAPPSPPASPPLSPLATPS---- 385
Query: 1267 IKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKS--------VPPSVP 1318
P+ + L S PP+ QA +PP SPP S PPS+
Sbjct: 386 --------PQAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPVSPSATPPSQAPPSLA 436
Query: 1319 ARGLQ--PQPPATPAVPH---PPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRN 1373
A LQ P PPA+P + PPP L + L L P P +
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLA-------APPLQLAKPPP-QAPPALATPP 488
Query: 1374 LETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP-----DGPPLAPAA 1428
L+ LPS + S S S +S L PP P + P PP +P
Sbjct: 489 LQALPSPPA----SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544
Query: 1429 AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP--------------- 1473
P PP PG P + +G L PPP P +P+ P
Sbjct: 545 QAPRRPPTPG-PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603
Query: 1474 --------------PPPPPQPAL---------PSPPPLVAPTPSSPPP-PPLPPP----- 1504
PPP + A P+PP P +P P PP P
Sbjct: 604 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663
Query: 1505 ---------PPPAMPSP---PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQ 1552
P A P+P P P P + A A S P+ L L Q
Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ 723
Query: 1553 ETAA--------VCGETDEEAGESGG 1570
+ + + AG SGG
Sbjct: 724 ASVVQHLLSRTLLLAAAEGAAGGSGG 749
Score = 56.6 bits (135), Expect = 2e-07
Identities = 129/574 (22%), Positives = 181/574 (31%), Gaps = 88/574 (15%)
Query: 1294 RHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353
R P +AG + P+S P + P R +PPA+ PP+ G +
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTR--TSRPPASGRGERAPPAKNTSPGPVSSPGRAS 112
Query: 1354 GLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGP 1413
G P K L E++VA+ + + SA+SA +GP
Sbjct: 113 GTTRPGPLGQKGL--------------RISAEETVARGKATEAPKRSALSAGARRDTSGP 158
Query: 1414 -------------KDTSTPDGPPLAPAAAVPGPP---PLPGLPSANSNGTPEPPLLEEKP 1457
+ T G P +A P PP P + SA+ + T EP +
Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPP 1517
P P + P + P TP +P P P P PP P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278
Query: 1518 PA--AAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFR 1575
P AAP P +P P P + P Q + +A S G +
Sbjct: 279 PRKDAAPALGPLSSSPLATPS-PSAPPS-PSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336
Query: 1576 ERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYF 1635
F+ P LA + PP + AL P +
Sbjct: 337 ATHSFL---PSPPLSPLATPPPQAPPAL-----ALPPLQAPPSPPASPPLSPLAT----- 383
Query: 1636 GDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPK 1695
+ L V L+ P PPV S A PVS S+ PP +
Sbjct: 384 -PSPQAPNALAVHLLQ----------APFSPPPSPPVQAPFSPPASPPVSP--SATPPSQ 430
Query: 1696 AP---------APPPKPETPEKTTSEKPPEQTP--------ETAMPEPPAPEKPSLLRPV 1738
AP PP P +P + S PP Q P + A P P AP P+L P
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATP- 487
Query: 1739 EKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPP--PK 1796
+ + G+ S + P LAT P + A +V PP P
Sbjct: 488 ----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 1797 KRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPS 1830
+ G T+ GP + + + P PS
Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Score = 46.2 bits (108), Expect = 3e-04
Identities = 91/355 (25%), Positives = 119/355 (33%), Gaps = 80/355 (22%)
Query: 1490 APTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL----AAPPEEPAAPSPEDPELPDTRP 1545
A TP++ P L P PP + P PPPP PAA + A +P A
Sbjct: 14 ARTPAARAPGLLTPRPPGS-PRPPPPVTPAALRVLGAAGAVGRKPLA------------- 59
Query: 1546 LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWR 1605
E AG GG I E P +T R PP R
Sbjct: 60 -----------------ERAGGIGGATI----------PESAPRAG-PTRTSR-PPASGR 90
Query: 1606 VQKALLQKFT---PEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVC 1662
++A K T P G+ LG G + + + K+ +
Sbjct: 91 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 150
Query: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPET--PEKTTSEKPPEQTPE 1720
AR+ P A+ +AG P AP+ P+P T P K+ S T E
Sbjct: 151 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210
Query: 1721 TAMPEPPAPEKPS----LLRPVEKEKEKEKVTRGERPLRGERATSGRQTR--PERSLATG 1774
P P A +PS L RP + ++ PL A SG R P
Sbjct: 211 ---PSPAARRRPSAGGGLQRPASR-----SLSSSATPL-SSPARSGPSARGTPRAPAHPS 261
Query: 1775 QPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAP 1829
QP L RP +V PP+K +A GP SS + SP AP
Sbjct: 262 QPKPKGLQALRPPQV---TPPRK----------DAAPALGPLSSSPLATPSPSAP 303
Score = 46.2 bits (108), Expect = 3e-04
Identities = 86/317 (27%), Positives = 114/317 (35%), Gaps = 54/317 (17%)
Query: 100 PQPGPSASSLLSQFRSPSWQT--AMHTPGPTELFIS--GALPGSSTFPSSSALSAYQHPA 155
PQ P ++ Q P Q A+ TP P + S + PG + F S++L
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLAT 518
Query: 156 SFGSRPFPVPSSLSLQDPPFSPPANGLLS----------------PHDVLHLKPSQAPTV 199
P PV ++ LQ PP SPPA+ L P L L P P
Sbjct: 519 PPPQAP-PVLAAPLLQVPP-SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP- 575
Query: 200 PSSLGFERLAGGGVLGPAGLG---PAQTPPYRPGPPD----PPPPPRHLPTQFNLLASSS 252
PS L+G + G + P + Y GP PPP L A+
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-------AACH 628
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQR--PASAQPPP---PPPPA 307
AA + + P + + AP P PP D + Y+ P SA P P P P+
Sbjct: 629 PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688
Query: 308 HALQHYLSCGGSYPSMGHR----ANLACSPLGGGEPSPGAGEPSK----AGPSGATAGAS 359
+ G+ R A L PLG + S S+ A GA G+
Sbjct: 689 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 748
Query: 360 GRATGPEAAGGGGAGGG 376
G GP A GGG GG
Sbjct: 749 G---GPGGAEGGGVTGG 762
Score = 34.7 bits (78), Expect = 0.98
Identities = 35/133 (26%), Positives = 41/133 (30%), Gaps = 13/133 (9%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPP-----KPETPEKTTSEKPPEQTPETAMP 1724
P P+ PV A PP PA P +P TP TS P T A
Sbjct: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 1725 EPPAPEK--PSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP 1782
PP P + S L + T LR G + PE A P + L
Sbjct: 572 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR------GYDSGPEGGAAASPPPDAELA 625
Query: 1783 KARPTKVKAEPPP 1795
P P P
Sbjct: 626 ACHPAAWSRGPAP 638
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 115 bits (287), Expect = 6e-25
Identities = 303/1203 (25%), Positives = 375/1203 (31%), Gaps = 260/1203 (21%)
Query: 158 GSRPFPVPSSLSLQDP-PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP 216
G+R P P + + P P P P P P LG A G++GP
Sbjct: 347 GNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGP 406
Query: 217 AGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSP--QLYNFSGAAPG 274
G P PG P P P + S A Q P + S PG
Sbjct: 407 PGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPG 466
Query: 275 PP-------PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRA 327
P PP P+ + K + + +P P PP G G +
Sbjct: 467 PQGIKGKVGPPGGRGPKGE---KGNEGLCACEPGPMGPPGPP--------GLPGRQGSKG 515
Query: 328 NLACSPLGG--GEPSPGAGE-----PSKAGPSG--ATAGASGRATGPEAAGGGGAGGGGG 378
+L G G+P P E P K G SG GA G G G G G
Sbjct: 516 DLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDG 575
Query: 379 GYRPIIQSPGYKTGKGGYG----AAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASG 434
PG+ G +G A G PP ATP + GP GKA
Sbjct: 576 -------PPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLG--PPGKAGP 626
Query: 435 AG-------GAGGQAYSPGQP--QGLLGPQAYGQGFGGGQAQDLSKAPSYSG-------- 477
G G G+ PG P G+ GP G G + +S +Y G
Sbjct: 627 VGPPGLGFPGPPGERGHPGVPGHPGVRGP----DGLKGQKGDTISCNVTYPGRHGPPGFD 682
Query: 478 GPPQPPSGPPP---PGLA-------------TCQSYSPDQLQGQL-----YGVQGEPYPG 516
GPP P P P PGL+ T + P +G + G +G G
Sbjct: 683 GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG 742
Query: 517 PAAHSQGLPTASPSLSYSTG--HSPALSGHGGGWGPSSLGG-------------GGEASP 561
P P SP ++ G PA GH G G L G G P
Sbjct: 743 PPG-----PPGSPGVNGQKGIPGDPAF-GHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGP 796
Query: 562 SHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFL-APPGAGSYAAGAGGYKGKGD 620
+ I L GR G PG PG S AP + PG Y G GKG
Sbjct: 797 AGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQ 856
Query: 621 ----------GSELLAG-PG-----GPPAERTEDEEFLIQHLLQAPSP------------ 652
G + L G PG GPP F L P P
Sbjct: 857 PGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF 916
Query: 653 ------PRTSGADGLVGEDGAADAS-----KGLGGSGGAGGPPGTPYELA----KEDPQR 697
P G G GE G S +GL G+ GA GPPG E+A K P
Sbjct: 917 PGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPG- 975
Query: 698 YHLQSVIRTSASLDEGATAAL-ELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
D+G + G ++ ++ P R G P G H G E
Sbjct: 976 -------EPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYG--PPGF-----HRG----EP 1017
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSA 816
G Q PP PP ST GL G P LP P P + P
Sbjct: 1018 GEKGQPGPPGPPGPPGST-----GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKG 1072
Query: 817 SKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP-RLRPEESLD 875
+K +PA+ G P P P P P G++ SP R P S
Sbjct: 1073 NKG-----DPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSG 1127
Query: 876 PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFP 935
PPG + + L PG+ G P DP P P G K P P +
Sbjct: 1128 PPGCPGD--HGMPGLRGQPGEMGDPGPRGLQGDPG----IPGPPGIKGPSGSP--GLNGL 1179
Query: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP------KAGAGPPPGPPAYDP 989
L + + ++ G G G D G P G PPGPP
Sbjct: 1180 HGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSS- 1238
Query: 990 YGPYCPGRASGAGPE---TPGLGLDPNKP-PELPSTVNAEP-----LGLIQSGPHQAAPP 1040
GP P A+G P+ PG D P P+ P P + L++ P P
Sbjct: 1239 -GPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP 1297
Query: 1041 PPPPPPPPPA-------PASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKK 1093
PP PP PP P + K G P+ F P+
Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGPV-----------------------GFPGPQ- 1333
Query: 1094 LYAQEYEFEADEDKADVPADI-RLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPG-PDG 1151
+ F + +P R P LP R P P D+D CP PG P
Sbjct: 1334 ---GPHGFPGPPGEKGLPGPPGRKGPTGLP----GPRGEP--GPPADVDDCPRIPGLPGA 1384
Query: 1152 PRRRG----------RKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPR 1201
P RG R P+ G P GR + VP + GP T P
Sbjct: 1385 PGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVD--GVPGSPGPPGRKGDTGEDGYPG 1442
Query: 1202 GRG 1204
G G
Sbjct: 1443 GPG 1445
Score = 99.0 bits (245), Expect = 4e-20
Identities = 240/984 (24%), Positives = 290/984 (29%), Gaps = 238/984 (24%)
Query: 135 ALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS 194
A PG FP P FP P + P P G+ P LK
Sbjct: 607 ATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGE--RGHPGVPGHPGVRGPDG---LKGQ 661
Query: 195 QAPTVPSSLGFERLAG----GGVLGPAGL-GPAQTP-----------PYRPGPPDPPPPP 238
+ T+ ++ + G G GP G GP P P PG + P PP
Sbjct: 662 KGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPP 721
Query: 239 RHLPTQ----FNLLASSSAAAAAAEQSSPQLYNFSGAAPGP------PPPERAL------ 282
F SS SP + G P PP +R L
Sbjct: 722 GFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGI 781
Query: 283 --PRQDTVIKHYQRPASAQ-----------------PPPPPPPAHALQHYLSCGGSYPSM 323
PR D + PA P P PP H SC P +
Sbjct: 782 KGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH------SCERGAPGI 835
Query: 324 GHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--GASGRATGPEAAGGGGAGG------ 375
+ L P G P G G+P GP G G G P A G G G
Sbjct: 836 PGQPGLPGYPGSPGAPG-GKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFG 894
Query: 376 --------GGGGYRPIIQSPGY--KTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAA 425
G G R + PG+ + GK G G P + P + L G
Sbjct: 895 DDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKG 954
Query: 426 AYATGKASGAGGAGGQAYSPGQP--------------------QGLLG-PQAYGQ-GFGG 463
A G Q +PG+P QG G P YG GF
Sbjct: 955 AIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHR 1014
Query: 464 GQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEP-YPGPAAHSQ 522
G+ + G P PP P PPG + + L G QGEP PGP
Sbjct: 1015 GEPGEK--------GQPGPPGPPGPPGSTGLRGFIGFP---GLPGDQGEPGSPGP----- 1058
Query: 523 GLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGS 582
P SG G GP G + P+ P P G P GS
Sbjct: 1059 ----------------PGFSGIDGARGPK----GNKGDPASHFGP---PGPKGEP---GS 1092
Query: 583 PGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGD--GSELLAGPGGPPAERTEDEE 640
PG PG + +S P + P G G G G + G G P E +
Sbjct: 1093 PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152
Query: 641 FLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAG----GPPGTPYELAKEDPQ 696
+Q P PP G G G +G G G +G GPPG
Sbjct: 1153 RGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP---------- 1202
Query: 697 RYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKEL 756
+G+ LK ++ P G +P G
Sbjct: 1203 -----------------------VGIPGLKGERGDPGSPGISPPGPRG------------ 1227
Query: 757 GAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP---QLLPSVLSHAPSPS 813
+K PP PP S P P G A P +P P P Q P +P
Sbjct: 1228 ----KKGPPGPP--GSSGPPGPAGATGRA-----PKDIPDPGPPGDQGPPGPDGPRGAPG 1276
Query: 814 PSASKVGVHLLEPATRD-GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAA--PSPRLRP 870
P V LL D G P PP PP PP PP G + P P+ P
Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ-GP 1335
Query: 871 EESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLT 930
PPG L P G TG+ P E PA P G
Sbjct: 1336 HGFPGPPGEK-----GLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPG------- 1383
Query: 931 SICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP-----PGPP 985
+ E P M G G + G G +G P GPP G
Sbjct: 1384 ----APGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVP-GSPGPPGRKGDTGED 1438
Query: 986 AYDPYGPYCPGRASGAGPETPGLG 1009
Y P GP PG GP+ G G
Sbjct: 1439 GY-PGGPGPPGPIGDPGPKGFGPG 1461
Score = 97.8 bits (242), Expect = 9e-20
Identities = 327/1317 (24%), Positives = 404/1317 (30%), Gaps = 290/1317 (22%)
Query: 344 GEPSKAGPSG--ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGG----YG 397
G P GP G +G +G P GG GA G GG + PG K KG G
Sbjct: 125 GHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGP----LGHPGEKGEKGNSVFILG 180
Query: 398 AAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAY 457
A G P P GGPA G G GQ PG+P GL G
Sbjct: 181 AVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQ---PGRP-GLKGNPGV 236
Query: 458 GQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGP 517
G G ++ + G P P PP C ++G + G+ G P P
Sbjct: 237 GVKGQMGDPGEVGQQ-----GSPGPTLLVEPPDF--CLYKGEKGIKG-IPGMVGLPGPPG 288
Query: 518 AAHSQGL-------------PTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHI 564
G+ P P SY + P L G G G L G +
Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPG-SYGSPGFPGLKGELGLVGDPGLFG--------L 339
Query: 565 IRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSEL 624
I P G P G PG PG ++ L P PPG + G Y GD
Sbjct: 340 IGP------KGDPGNRGHPGPPGVLVTPPL---PLKGPPGDPGFP---GRYGETGD---- 383
Query: 625 LAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGE---DGAADASKGLGGSGGAG 681
GP GPP E ++ P P G GL GE G D++ G G G+
Sbjct: 384 -VGPPGPPGLLGRPGE-ACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSP 441
Query: 682 GPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEG 741
G PG P Q SVI S G +K K P GG P+G
Sbjct: 442 GLPGAP------GLQGLPGSSVIYCSVG---------NPGPQGIKGKVGPP--GGRGPKG 484
Query: 742 LATSVVHYGAGAKELGAFLQKSPPPPP--PTAQSTQPT--PHGLLLEAGGPDLPLVLPPP 797
+ G A E G PP PP P Q ++ G L G P P PP
Sbjct: 485 ---EKGNEGLCACEPGPM---GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPP 538
Query: 798 PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSH 857
LP + P +K + + G P PP P P + H
Sbjct: 539 G---LPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEK 595
Query: 858 GLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG-VGPPNSEGKDPAGAYRSP 916
G +P P E P G G PL P PG G VGPP P G P
Sbjct: 596 G-DPGPPG----DHEDATPGGK-----GFPGPLGP-PGKAGPVGPPGLGFPGPPGERGHP 644
Query: 917 SPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKA 976
G R PD L + + + G+ GPP +G
Sbjct: 645 GVPGHPGVR--------GPDGLKGQKGDTISCNVTYP---------GRHGPPGFDG---- 683
Query: 977 GAGPPPGPPAYDPYGPYCPGRASGAG----PETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032
PPGP + P PG + G P TPG P PP + G
Sbjct: 684 ----PPGPKGF-PGPQGAPGLSGSDGHKGRPGTPGTAEIPG-PPGFRGDMGDPGFG---- 733
Query: 1033 GPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPK 1092
G ++P PP PP P + KG P F P S P + P+
Sbjct: 734 GEKGSSPVGPPGPPGSPG-VNGQKGIPGDPAFGHLGPPGKRGLSGV-------PGIKGPR 785
Query: 1093 KLYAQEYEFEADEDKADVPADIRLNPRR-------LPDLVS----SC-RSRPALSPLGDI 1140
+ E A +P + L + P + SC R P + +
Sbjct: 786 ----GDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841
Query: 1141 DFCPPNPG-PDGPRRRG--RKPTKAKRDGPPRPRGRPRIR-PLEVPTTAGP--ASASTPT 1194
P +PG P G + G P A G P GRP P +P GP
Sbjct: 842 PGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGP 901
Query: 1195 DGAKKPRG-------RGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAIS 1247
G K PRG G AE G + EP + +S GL + G
Sbjct: 902 PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEK---GMSGLPGDRGLRGAKGAIGP 958
Query: 1248 GTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPL 1307
D + I ++ E P GF + K P + P
Sbjct: 959 PGDEGEM-------AIISQKGTPGEPGPPGDDGFPGE-----RGDKGTPGMQGRRGEPGR 1006
Query: 1308 SPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGG-----ALEAAESEGLGLGCPSP 1362
P P QP PP P P G+ GL G L + E G P P
Sbjct: 1007 YGPPGFHRGEPGEKGQPGPPGPPG-----PPGSTGLRGFIGFPGLPGDQGEP---GSPGP 1058
Query: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGP 1422
P FS + R + + S P GPK P P
Sbjct: 1059 ---------------PGFS-----GIDGARGPKGNKGDPASHFGPP---GPK--GEPGSP 1093
Query: 1423 PLAPAAAVPGPPPLPGLPS-ANSNGTPEPPLLEEKPPPTP----PPAPTPQP----QPPP 1473
G LPG+ S G P PP PP P P QP P P
Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPP-GSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152
Query: 1474 PPPPPQPALPSPPPLVAPT----------------------------------------- 1492
P +P PP + P+
Sbjct: 1153 RGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGER 1212
Query: 1493 --PSSP---PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE--EPAAPSPEDPELPD 1542
P SP PP P PP P PP PA A AP + +P P + P PD
Sbjct: 1213 GDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPD 1269
Score = 83.6 bits (205), Expect = 2e-15
Identities = 326/1336 (24%), Positives = 392/1336 (29%), Gaps = 312/1336 (23%)
Query: 344 GEPSKAGPSGATA-GASGRATGPEAAGGGGAGGGGG-----GYRPIIQSPGYKTGKGGYG 397
G P + G SG A G G P G G+ G G G ++ PG G G
Sbjct: 285 GPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL-FGLIGPK 343
Query: 398 AAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAG-----GQAYSPGQP-QGL 451
G P PP TP G P G+ G G G PG+ G+
Sbjct: 344 GDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGM 403
Query: 452 LGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQG 511
+GP QGF G L P +G P +P S P PG + SP G+ G
Sbjct: 404 IGPPG-PQGFPG-----LPGLPGEAGIPGRPDSAPGKPG----KPGSP--------GLPG 445
Query: 512 EPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGP-SSLGGGGEASPSHIIRPLQS 570
P QGLP +S + Y + +P G G GP G GE +
Sbjct: 446 AP------GLQGLPGSS--VIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPG 497
Query: 571 PPATGRPPGV-GSPGAPGKY-LSSVLASAPFLAPPGA-------GSY-AAGAGGYKG-KG 619
P PPG+ G G+ G L L + PPGA G + A+G G KG KG
Sbjct: 498 PMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKG 557
Query: 620 D-------GSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAA---- 668
D G + GP GPP P P + G DG GE G
Sbjct: 558 DMVVSRVKGHKGERGPDGPPG---------------FPGQPGSHGRDGHAGEKGDPGPPG 602
Query: 669 ---DASKGLGGSGGAGGPPGT-----PYELAKEDP--QRYHLQSVIRTSASLDEGATAAL 718
DA+ G G G GPPG P L P +R H +G
Sbjct: 603 DHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQK 662
Query: 719 --ELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQP 776
+ + GP G + P G GA G+ K P P TA+ P
Sbjct: 663 GDTISCNVTYPGRHGPP-GFDGPPGPKGFPGPQGAPGLS-GSDGHKGRPGTPGTAEI--P 718
Query: 777 TPHGLLLEAGGPDL-----PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD- 830
P G + G P + PP P P V P A HL P R
Sbjct: 719 GPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG---HLGPPGKRGL 775
Query: 831 ----GAPQPPPPPPPPPPPMPLQLEAHL--------RSHGLEPAAPSPRLRPEESLDPPG 878
G P P P P + L H P P P E P
Sbjct: 776 SGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGI 835
Query: 879 AMQELLGALEPLPPAPGDTG----VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICF 934
Q L P APG G VGPP PAG P G P
Sbjct: 836 PGQPGLPGYPGSPGAPGGKGQPGDVGPPG-----PAGMKGLPGLPGRPGAHGPP------ 884
Query: 935 PDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP--PGPPAY--DPY 990
P + FG D G GPP PK G P PG P P
Sbjct: 885 -----------GLPGIPGPFG-----DDGLPGPP----GPKGPRGLPGFPGFPGERGKPG 924
Query: 991 GPYCPGRASGAGPE----TPG-LGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPP 1045
CPG G + PG GL K P E + Q G P P PP
Sbjct: 925 AEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKG----TPGEPGPP 980
Query: 1046 PPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADE 1105
P +G +P RR +P P + E +
Sbjct: 981 GDDGFPGE--RGDKGTPGMQG---------------RRGEPGRYGPPGFHRGEPGEKGQP 1023
Query: 1106 DKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGP------DGPRR-RGRK 1158
P P + R L P +PGP DG R +G K
Sbjct: 1024 GPPGPPG---------PPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNK 1074
Query: 1159 PTKAKRDGPPRPRGRPRIR-------------------PLEVPTTAGPASASTPTDGAKK 1199
A GPP P+G P P P GP +S P G
Sbjct: 1075 GDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPP-GCPG 1133
Query: 1200 PRGRGRGRGRKAEEAG----GTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLD 1255
G RG+ E G + +P P + P GL G
Sbjct: 1134 DHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHG------------ 1181
Query: 1256 SSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPP 1315
L +K + + P G G+R P G++PP K PP
Sbjct: 1182 --LKGQKGTKGASGLHDVGPPGPVGIPGL------KGERGDP-GSPGISPPGPRGKKGPP 1232
Query: 1316 SVPARGLQPQPP-----ATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEEL 1370
P P P A +P P P G G G +G G P P
Sbjct: 1233 GPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGP------DG-PRGAPGP-------- 1277
Query: 1371 KRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPP------- 1423
L S+ D L GP P GPP
Sbjct: 1278 ---------------------PGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPG 1316
Query: 1424 ------LAPAAAVPGPPPLPGLPS-ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPP 1476
PGP G P G P PP + PT P P +P PP
Sbjct: 1317 CDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPP---GRKGPTGLPGPRGEPGPPADVD 1373
Query: 1477 --PPQPALPSPPPLVAPTPSSPPPPPLPPPPP-----PAMPS-------PPPPPPPAAAP 1522
P P LP P + P + P P P P + P P PP
Sbjct: 1374 DCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKG 1433
Query: 1523 LAAPPEEPAAPSPEDP 1538
P P P P
Sbjct: 1434 DTGEDGYPGGPGPPGP 1449
Score = 54.7 bits (130), Expect = 9e-07
Identities = 73/265 (27%), Positives = 83/265 (31%), Gaps = 52/265 (19%)
Query: 1305 PPLSPPKSVPPSVPARGLQPQPPATPA-----VPHPPPSGAFGLGGALEAAESEGLGLGC 1359
P + P P GL+ Q A V P P G GL G E + G+
Sbjct: 1165 PGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG--ERGDPGSPGISP 1222
Query: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
P P K+ P S + A R A + DP G + P
Sbjct: 1223 PGP------RGKKGPPGPPGSSGPPGPAGATGR--------APKDIPDPGPPGDQGPPGP 1268
Query: 1420 DGPPLAPAAAVPGPPPLPGLPSA-----NSNGTPEPPLLEEKPPPTPP------------ 1462
DGP PGPP LPG G P PP PP PP
Sbjct: 1269 DGP-----RGAPGPPGLPGSVDLLRGEPGDCGLPGPP--GPPGPPGPPGYKGFPGCDGKD 1321
Query: 1463 ----PAPTPQPQPPP--PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516
P P PQ P P PP + LP PP PT P P P PP P P
Sbjct: 1322 GQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPT-GLPGPRGEPGPPADVDDCPRIPG 1380
Query: 1517 PPAAAPLAAPPEEPAAPSPEDPELP 1541
P A + P P P P
Sbjct: 1381 LPGAPGMRGPEGAMGLPGMRGPSGP 1405
Score = 51.2 bits (121), Expect = 1e-05
Identities = 105/440 (23%), Positives = 129/440 (29%), Gaps = 72/440 (16%)
Query: 65 PAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHT 124
P G SG+ G+ GP + + S GP+ P + F + Q
Sbjct: 1058 PPGFSGI-------DGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGI 1110
Query: 125 PGPTELFISGALPGSSTFPSSSALSAYQ----HPASFGSRPFP--------VPSSLSLQD 172
GP PGSS P P G P P +P ++
Sbjct: 1111 QGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGD-PGPRGLQGDPGIPGPPGIKG 1169
Query: 173 PPFSPPANGL------------LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLG 220
P SP NGL HDV P P + G G GP G
Sbjct: 1170 PSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKK 1229
Query: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
PP GPP P P +Q P GA PGPP
Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDI------PDPGPPGDQGPPGPDGPRGA-PGPP---- 1278
Query: 281 ALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPS 340
LP +++ PP PP Y G G + P+G P
Sbjct: 1279 GLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKG-----PVGFPGPQ 1333
Query: 341 PGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
G P G G G GR G G G + PG G G
Sbjct: 1334 GPHGFPGPPGEKGLP-GPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPE- 1391
Query: 401 GGATRPPPPRSTATPKCQ----------------SLGGPAAAYATGKASGAGGAGGQAYS 444
GA P R + P C+ S G P TG+ GG G
Sbjct: 1392 -GAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPG----- 1445
Query: 445 PGQPQGLLGPQAYGQGFGGG 464
P P G GP+ +G G+ GG
Sbjct: 1446 PPGPIGDPGPKGFGPGYLGG 1465
Score = 51.2 bits (121), Expect = 1e-05
Identities = 45/150 (30%), Positives = 52/150 (34%), Gaps = 27/150 (18%)
Query: 1421 GPPLAPAAAVPGPPPLPGLPS-ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQ 1479
G P +P + PGP G P S+G P P + P P P Q PP P P+
Sbjct: 1213 GDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPR 1272
Query: 1480 -----PALPSPPPLVAPTPS-----SPPPPPLPPPPPPAMPSP--------------PPP 1515
P LP L+ P PP PP PP PP P P P
Sbjct: 1273 GAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332
Query: 1516 PPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
P P PP E P P + P P
Sbjct: 1333 QGPHGFP--GPPGEKGLPGPPGRKGPTGLP 1360
Score = 50.1 bits (118), Expect = 2e-05
Identities = 44/155 (28%), Positives = 52/155 (33%), Gaps = 19/155 (12%)
Query: 1407 DPPLAGPKDTSTPDGPP-LAPAAAVPGPPPLPGLPSANSNGTPEPP----LLEEKPPPTP 1461
DP + GP P G P L + G G + G P P L E+ P
Sbjct: 1158 DPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGS 1217
Query: 1462 PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAA 1521
P P P+ PP P P PP T + P +P P PP PP P P A
Sbjct: 1218 PGISPPGPRGKKGPPGP-PGSSGPPGPAGATGRA--PKDIPDPGPPGDQGPPGPDGPRGA 1274
Query: 1522 P-----------LAAPPEEPAAPSPEDPELPDTRP 1545
P L P + P P P P P
Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPP 1309
Score = 40.8 bits (94), Expect = 0.014
Identities = 56/223 (25%), Positives = 69/223 (30%), Gaps = 52/223 (23%)
Query: 1405 LDDPPLAGPKDTST--PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP----- 1457
+ DP G K +S P GPP +P V G +PG P+ G P L P
Sbjct: 727 MGDPGFGGEKGSSPVGPPGPPGSP--GVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGP 784
Query: 1458 ------PPTPPPAPTP-------------------QPQPP-------PPPPPPQPALPSP 1485
P PA P P PP P P QP LP
Sbjct: 785 RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGY 844
Query: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP-------PPAAAPLAAPPEEPAAPSPEDP 1538
P P + PP P M P P PP + P + P P P
Sbjct: 845 PGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGP 904
Query: 1539 E----LPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRER 1577
+ LP + + A C E GE G G+ +R
Sbjct: 905 KGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 114 bits (286), Expect = 7e-25
Identities = 289/1153 (25%), Positives = 361/1153 (31%), Gaps = 285/1153 (24%)
Query: 80 GSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGS 139
G GP N + + +G GP L+ P A PGP PG
Sbjct: 66 GPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPG---AAGAPGPQGFQGPAGEPGE 122
Query: 140 STFPSSSALSAYQHPASFGSRPFPVPSSLSLQD----PPFSPPANGLLSPHDVLHLKPSQ 195
P + + + PA P + +D P P G++ P
Sbjct: 123 ---PGQTGPAGARGPAG--------PPGKAGEDGHPGKPGRPGERGVVGPQGARGF---- 167
Query: 196 APTVPSSLGFERLAG----GGVLGPAGLGPAQTPPYRPGPPDPPPPP--RHLPTQFNLLA 249
P P GF+ + G G+ G G + P PG P R LP + +
Sbjct: 168 -PGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVG 226
Query: 250 SSSAAAAAAEQSSPQLYNFSG-----------AAPGPP----------PPERALPRQDTV 288
+ A A S +G APGP P A PR +
Sbjct: 227 APGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG 286
Query: 289 IKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSK 348
+ P PP P A+ L G +A +P G P P G P
Sbjct: 287 LPGLSGPVG---PPGNPGANGLTGAKGAAGL-------PGVAGAP---GLPGP-RGIPGP 332
Query: 349 AGPSGATA-----GASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGA 403
G +GAT G G A +G G G G P P + GK G AG A
Sbjct: 333 VGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGP--PGPSGEEGKRGPNGEAGSA 390
Query: 404 TRPPPPRSTATPKCQSLGG----------PAAAYATGKASGAGGAGGQAYSPGQPQGLLG 453
P PP +P + L G P + A+G A G G G A PG+P GL+G
Sbjct: 391 GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPA-GVRGPNGDAGRPGEP-GLMG 448
Query: 454 PQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEP 513
P+ G G G P P P G A G +GEP
Sbjct: 449 PR----GLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPA---------------GARGEP 489
Query: 514 ----YPGPAAHSQGLPTASPSLSYSTGHS--------PALSGHGGGWGPSS----LGGGG 557
+PGP PT P + GH+ P G+ G GP GG G
Sbjct: 490 GNIGFPGPKG-----PTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKG 544
Query: 558 EASPSHIIRPLQSPPATGRPPG-VGSPGAPGKY----LSSVLASAPFLAPPGAGSYAAGA 612
E P Q P P G VG PG G + L PPG A
Sbjct: 545 EQGPPGP-PGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPT 603
Query: 613 G--GYKG----------KGD----GSELLAGPGGP------------PAERTEDEEFLIQ 644
G G +G KG+ G+ AGP GP P + E E ++
Sbjct: 604 GPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR 663
Query: 645 HLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAG-----GPPGTPYELAKEDPQRYH 699
+ P GA G VG G A A+ G +G AG GP G+P E + P
Sbjct: 664 GEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGP---- 719
Query: 700 LQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAF 759
A + A A G + KG ERG + P+G V G +GA
Sbjct: 720 --------AGPNGFAGPAGAAG----QPGAKG-ERGAKGPKGENGVVGPTG----PVGAA 762
Query: 760 LQKSP-PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASK 818
P PP P P G+ G P PP PS +S P P A K
Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGM---TGFPGAAGRTGPPG----PSGISGPPGPPGPAGK 815
Query: 819 VGVHLLE----PATRD---GAPQPP----------------PPPPPPP-----PPMPLQL 850
G+ P R GA PP PP P P P L L
Sbjct: 816 EGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGL 875
Query: 851 EAHLRSHGLEPAA-----PSPR--LRPEESLDPPGAMQELLGALEPLPPAPGDTG----- 898
GL A P P P + PPGA+ + APG+ G
Sbjct: 876 PGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAV-----GSPGVNGAPGEAGRDGNP 930
Query: 899 --VGPPNSEGK-------------DPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEE 943
GPP +G+ P GA +P P G P +
Sbjct: 931 GNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAG-------------KHGN 977
Query: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDP-KAGAGPPPGPPAY--------------- 987
R + GA G +GP GD + G P G P
Sbjct: 978 RGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGH 1037
Query: 988 --DPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPP 1045
D P G A GP P + P TV P G+ HQ P PP P
Sbjct: 1038 HGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVG--PAGIRGPQGHQ-GPAGPPGP 1094
Query: 1046 PPPPAPASEPKGG 1058
P PP P GG
Sbjct: 1095 PGPPGPPGVSGGG 1107
Score = 100 bits (248), Expect = 2e-20
Identities = 228/914 (24%), Positives = 272/914 (29%), Gaps = 171/914 (18%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPR---HLPTQFNL-----------LASSSAAAAA 257
G GP G P PGPP PP PP + Q++ L A
Sbjct: 45 GPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGA 104
Query: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH-------AL 310
A PQ + PG P + + P P P
Sbjct: 105 AGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGA 164
Query: 311 QHYLSCGGSYPSMGHRANLACSPLGGGEPSPGA-GEPSKAGPSGATA--------GASGR 361
+ + G G R + L G +PG GEP G +G G GR
Sbjct: 165 RGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGR 224
Query: 362 ATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG-----GATRPPPPRSTATPK 416
P AG G+ G G P P G G+ A G GA P A P+
Sbjct: 225 VGAPGPAGARGSDGSVGPVGPA--GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPR 282
Query: 417 CQ----SLGGPAAAYATGKASGAGGAGGQAYSPGQ--------PQGLLGPQAYG-----Q 459
+ L GP A+G GA G A PG P+G+ GP +
Sbjct: 283 GEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGAR 342
Query: 460 GFGGGQAQDLSKAPSYSGGPPQP--PSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGP 517
G G SK S + G P P GPP P G +G+ P
Sbjct: 343 GLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS-----------------GEEGKRGPNG 385
Query: 518 AAHSQGLPTASPSLSYSTGHS--PALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATG 575
A S G P P L S G P G G GP G G + P+ + P G
Sbjct: 386 EAGSAG-PPGPPGLRGSPGSRGLPGADGRAGVMGPP--GSRGASGPAGVRGPNGDAGRPG 442
Query: 576 RPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAER 635
P +G G PG +P P G G G+ GP GP R
Sbjct: 443 EPGLMGPRGLPG---------SPGNIGPAGKEGPVGLPGIDGR-------PGPIGPAGAR 486
Query: 636 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDP 695
E + P P +G G G+ G A GL G+ GA GP G P
Sbjct: 487 GEPGN------IGFPGPKGPTGDPGKNGDKGHA----GLAGARGAPGPDGNNGAQGPPGP 536
Query: 696 QRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYG----- 750
Q +Q L G E K ERG GL G
Sbjct: 537 Q--GVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPP 594
Query: 751 ---AGAKELGAFLQKSPP-PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVL 806
A G + P PP P +P G + AG P P LP
Sbjct: 595 GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAG---------PSGPSGLPGER 645
Query: 807 SHAPSPSPSASKVGVHL---LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHG-LEPA 862
A P K L + RDGA P P P + G PA
Sbjct: 646 GAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPA 705
Query: 863 AP--SPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEG--KDPAGAYRSPSP 918
P SP R E P GA P A G+ G P E P G + P
Sbjct: 706 GPRGSPGERGEVGPAGPNGFAGPAGAAGQ-PGAKGERGAKGPKGENGVVGPTGPVGAAGP 764
Query: 919 QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP-KAG 977
G P G A G GPP G P AG
Sbjct: 765 AGPNGP-------------------------------PGPAGSRGDGGPPGMTGFPGAAG 793
Query: 978 AGPPPGPPAYD-PYGPYCPGRASGAGPETPGLGLDP-NKPPELPSTVNAEPLGLIQSGPH 1035
PPGP P GP PG A G P P + E+ + P + GP
Sbjct: 794 RTGPPGPSGISGPPGP--PGPAGKEGLRGPRGDQGPVGRTGEVGAV--GPPGFAGEKGPS 849
Query: 1036 QAAPPPPPPPPPPP 1049
A PP P P
Sbjct: 850 GEAGTAGPPGTPGP 863
Score = 85.5 bits (210), Expect = 5e-16
Identities = 207/792 (26%), Positives = 253/792 (31%), Gaps = 129/792 (16%)
Query: 344 GEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG-- 401
GE GP G G G P G G G GG + G G G G
Sbjct: 42 GERGPPGPPGRD-GEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100
Query: 402 --GATRPPPPRSTATPKCQ----SLGGPAAAYATGKASGAGGAGGQAYSPGQP--QGLLG 453
GA P P+ P + GPA A G G G PG+P +G++G
Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160
Query: 454 PQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSP-DQLQGQ--LYGVQ 510
PQ +GF P P PG + ++ D L+GQ GV+
Sbjct: 161 PQG-ARGF---------------------PGTPGLPGFKGIRGHNGLDGLKGQPGAPGVK 198
Query: 511 GEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQS 570
GEP P + T + L G A G S+G G A P P
Sbjct: 199 GEP-GAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF 257
Query: 571 PPATGRPPG----VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSEL-- 624
P A G P G VG+ G G P L+ P GA G G + L
Sbjct: 258 PGAPG-PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPG 316
Query: 625 LAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADG---LVGEDGAADA-----SKGLGG 676
+AG G P R P P +GA G LVGE G A + +KG G
Sbjct: 317 VAGAPGLPGPRG------------IPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPG 364
Query: 677 SGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP--ER 734
S G GPPG E K P + L G+ + L + GP R
Sbjct: 365 SAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGL-RGSPGSRGLPGADGRAGVMGPPGSR 423
Query: 735 GGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAG--GPDLPL 792
G P G+ G + + P P + + P GL G GP P
Sbjct: 424 GASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPA 483
Query: 793 VLPPPPPQL-LPSVLSHAPSPSPSASKVGVHLL------EPATRDGAPQPP--------- 836
P + P P + K L P +GA PP
Sbjct: 484 GARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGK 543
Query: 837 ----PPPPP-----PPPPMPLQLEAHLRSHGL--EPAAPSPRLRPEESLDPPGAMQELLG 885
PP PP P P P GL E P P P PPG G
Sbjct: 544 GEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGP-AGPRGERGPPGES----G 598
Query: 886 ALEPLPPAPGDTGVGPPNSEG-KDPAGAYRSPSPQGTKAPRFVP--LTSICFPDSLLQDE 942
A P P GPP +G K G + G P +P + P +
Sbjct: 599 AAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKG 658
Query: 943 ERSFFPTMEEMFGG-------GAADDYGKAGPPEDEGD-PKAGAGPPPGPPAYDPYGPYC 994
E P + G GA G GP GD +AGA P GP P G
Sbjct: 659 E----PGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAG--PRG--S 710
Query: 995 PGRASGAGPETP-------GLGLDPNKPPELPSTVNAEPLGLI-QSGPHQAAPPPPPPPP 1046
PG GP P G P E + G++ +GP AA P P P
Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP 770
Query: 1047 PPPAPASEPKGG 1058
P PA S GG
Sbjct: 771 PGPA-GSRGDGG 781
Score = 82.4 bits (202), Expect = 4e-15
Identities = 135/479 (28%), Positives = 165/479 (34%), Gaps = 103/479 (21%)
Query: 193 PSQAPTVPSSLGFERLAGG-----GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNL 247
P+ A P + G ER A G GV+GP G A P GPP P
Sbjct: 728 PAGAAGQPGAKG-ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP------------- 773
Query: 248 LASSSAAAAAAEQSSPQLYNFSGAA--PGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305
A + + P + F GAA GPP P + PP PP
Sbjct: 774 ------AGSRGDGGPPGMTGFPGAAGRTGPPGPS----------------GISGPPGPPG 811
Query: 306 PAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGP 365
PA G G R + P+G G P AG G + G +G A P
Sbjct: 812 PA----------GKEGLRGPRGDQG--PVGRTGEVGAVGPPGFAGEKGPS-GEAGTAGPP 858
Query: 366 EAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAA 425
G G G G I+ PG + +G G A GA P P A P GP
Sbjct: 859 GTPGPQGLLGAPG----ILGLPGSRGERGLPGVA--GAVGEPGPLGIAGPP--GARGPPG 910
Query: 426 AYATGKASGAGGAGGQAYSPGQ--PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQP- 482
A + +GA G G+ +PG P G G G G + + P + G P P
Sbjct: 911 AVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQP----GHKGERGYPGNIGPVGAAGAPGPH 966
Query: 483 ----------------PSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPT 526
PSGP P A P QG + G +GEP + P
Sbjct: 967 GPVGPAGKHGNRGETGPSGPVGPAGAVGPR-GPSGPQG-IRGDKGEP-------GEKGPR 1017
Query: 527 ASPSLSYSTGHS--PALSGHGGGWG-PSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSP 583
P L G P ++GH G G P S+G G P+ P TG P VG
Sbjct: 1018 GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPA 1077
Query: 584 GAPGKYLSSVLASAPFLAPPG-AGSYAAGAGGYKGKGDGSELLAG-PGGPPAERTEDEE 640
G G A P PPG G GGY DG A P P+ R +D E
Sbjct: 1078 GIRGPQGHQGPAGPP--GPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYE 1134
Score = 64.7 bits (156), Expect = 9e-10
Identities = 167/625 (26%), Positives = 194/625 (31%), Gaps = 119/625 (19%)
Query: 465 QAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGL 524
Q + + K P+ GP P PPG D G PGP
Sbjct: 26 QEETVRKGPAGDRGPRGERGPPGPPG-----RDGEDGPTGP---------PGPPG----- 66
Query: 525 PTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPG 584
P P L + G G G GP +G G P +P G G PG
Sbjct: 67 PPGPPGL--GGNFAAQYDGKGVGLGPGPMGLMGPRGPP---GAAGAPGPQGFQGPAGEPG 121
Query: 585 APGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQ 644
PG+ A P PPG AG G+ GK G G GP R
Sbjct: 122 EPGQ-TGPAGARGP-AGPPG----KAGEDGHPGK-PGRPGERGVVGPQGAR--------- 165
Query: 645 HLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVI 704
P P G G+ G +G D KG G+ G G PG P E Q+
Sbjct: 166 ---GFPGTPGLPGFKGIRGHNG-LDGLKGQPGAPGVKGEPGAPGENGTPG------QTGA 215
Query: 705 RTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGA-GAK-ELGAFLQK 762
R + G A R + GP G P G A GA G K E+GA
Sbjct: 216 RGLPG-ERGRVGAPGPAGARGSDGSVGPV-GPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273
Query: 763 SPPPPP-------------PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHA 809
P P P P +GL G LP V P LP
Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG---LPGPRG-I 329
Query: 810 PSPSPSASKVGVHLL--EPAT-----RDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPA 862
P P +A G L EP G P P PP P E +G +
Sbjct: 330 PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS 389
Query: 863 APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV-GPPNSEG-------KDPAGAYR 914
A P PPG LP A G GV GPP S G + P G
Sbjct: 390 AGPP--------GPPGLRGS--PGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAG 439
Query: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGG--GAADDYGKAGPPEDEG 972
P G PR +P + P +E G G G GP G
Sbjct: 440 RPGEPGLMGPRGLP------------GSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG 487
Query: 973 DPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032
+P P P P DP G A AG G D N + P P G +Q
Sbjct: 488 EPGNIGFPGPKGPTGDPGKNGDKGHAGLAGAR-GAPGPDGNNGAQGP----PGPQG-VQG 541
Query: 1033 GPHQAAPPPPP---PPPPPPAPASE 1054
G + PP PP P P PA E
Sbjct: 542 GKGEQGPPGPPGFQGLPGPSGPAGE 566
Score = 46.2 bits (108), Expect = 3e-04
Identities = 64/249 (25%), Positives = 80/249 (32%), Gaps = 36/249 (14%)
Query: 1314 PPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAA-ESEGLGLGCPSPCKRLDEELKR 1372
PP P R + P P P PP G GLGG A + +G+GLG P P +
Sbjct: 46 PPGPPGRDGEDGPTGPPGPPGPP--GPPGLGGNFAAQYDGKGVGLG-PGPMGLMGPRGPP 102
Query: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP------ 1426
P + + Q + A AGP + DG P P
Sbjct: 103 GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP------AGPPGKAGEDGHPGKPGRPGER 156
Query: 1427 -------AAAVPGPPPLPGLPSANSN-------GTPEPPLLEEKPPPTPPPAPTPQPQPP 1472
A PG P LPG + G P P ++ + P P TP
Sbjct: 157 GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGE-PGAPGENGTPGQTGA 215
Query: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP-----PPAMPSPPPPPPPAAAPLAAPP 1527
P + + +P P A P P P PP P P P A A P
Sbjct: 216 RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGP 275
Query: 1528 EEPAAPSPE 1536
PA P E
Sbjct: 276 AGPAGPRGE 284
Score = 45.8 bits (107), Expect = 4e-04
Identities = 203/877 (23%), Positives = 267/877 (30%), Gaps = 177/877 (20%)
Query: 766 PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLE 825
P P + P P G AG P P P + A P+ K G
Sbjct: 98 PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGP----------AGARGPAGPPGKAG----- 142
Query: 826 PATRDGAPQPPPPPP-------------PPPPPMP--LQLEAHLRSHGLEPAAPSPRLRP 870
DG P P P P P +P + H GL+ +P ++
Sbjct: 143 ---EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKG 199
Query: 871 EESLDPPGAMQELLGALEPLPPAPGDTGV-GPPNSEGK----DPAGAYRSPSPQGTKAPR 925
E PGA E PG TG G P G+ PAGA S G P
Sbjct: 200 E-----PGAPGE--------NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPA 246
Query: 926 FVPLTSICFPDSLLQDEERSFFPTME----EMFGGGAADDYGKAGPPEDEGDPKAGAGPP 981
P+ S P FP E+ G A G AGP + G P G P
Sbjct: 247 G-PIGSAGPPG----------FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLP--GLSGP 293
Query: 982 PGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE--LPSTVNAEPL----GLI-QSGP 1034
GPP +P G AG PG+ P P +P V A GL+ + GP
Sbjct: 294 VGPPG-NPGANGLTGAKGAAG--LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350
Query: 1035 HQA-------APPPPPPPPPPPAPASE-----PKG-----GLTSPIFCSTKPKKLLKTSS 1077
+ P P PP P+ E P G G P P +
Sbjct: 351 AGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGA 410
Query: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPL 1137
PP A D + P + PR LP + P+
Sbjct: 411 DGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG--LMGPRGLPGSPGNIGPAGKEGPV 468
Query: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRP-RIRPLEVPTTAGPASASTP--T 1194
G + PGP GP +P GP P G P + AG A P
Sbjct: 469 G-LPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGN 527
Query: 1195 DGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSL 1254
+GA+ P G +G K E+ P +GL SG A
Sbjct: 528 NGAQGPPGPQGVQGGKGEQGPPG--------------PPGFQGLPGPSGPA--------- 564
Query: 1255 DSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVP 1314
++ + E+ + G G+R PP ++G P P S
Sbjct: 565 ----------GEVGKPGERGLHGEFGLPGPAGP---RGERGPP-GESGAAGPTGPIGSRG 610
Query: 1315 PSVPAR--GLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKR 1372
PS P G + +P AV PSG GL G AA G G G ++ + L+
Sbjct: 611 PSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPG-GKG-----EKGEPGLRG 664
Query: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432
+ RD A+ A G + + GP PA
Sbjct: 665 EIGN-------------PGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPA-GPAGPRGS 710
Query: 1433 PPPLPGLPSANSNGTPEP------PLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP 1486
P + A NG P P + + P P P PA P+ P
Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP 770
Query: 1487 PLVAPTPSSPPPPPLP----------PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE 1536
P A + PP + PP P + PP PP PA P P
Sbjct: 771 PGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGR 830
Query: 1537 DPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGI 1573
E+ P A ++ + G T G G +G+
Sbjct: 831 TGEVGAVGPPGFAGEKGPSGEAG-TAGPPGTPGPQGL 866
Score = 45.1 bits (105), Expect = 7e-04
Identities = 79/284 (27%), Positives = 96/284 (33%), Gaps = 75/284 (26%)
Query: 826 PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSH------GLEPAAPSPRLRPEESLDPPGA 879
P RDG P PP PP PP P L + + GL P P + P PPGA
Sbjct: 49 PPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP-GPMGLMGPR---GPPGA 104
Query: 880 MQELLGALEPL--------PPAPGDTG-------VGPPNSEGKD-PAGAYRSPSPQGTKA 923
GA P P PG TG GPP G+D G P +G
Sbjct: 105 ----AGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160
Query: 924 PRFVPLTSICFPDSLLQDEERSFFPTMEEMFG----------GGAADDYGKAGPPEDEGD 973
P+ + FP + P + + G GA G+ G P + G
Sbjct: 161 PQ----GARGFPGT-------PGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGT 209
Query: 974 P-------------KAGAGPPPGPPAYD----PYGPYCPGRASGAGPETPGLGLDPNKPP 1016
P + GA P G D P GP G AGP PG P
Sbjct: 210 PGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGP--AGPIGSAGP--PGFPGAPGPKG 265
Query: 1017 ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLT 1060
E+ + NA P G +GP P P P P + GLT
Sbjct: 266 EIGAVGNAGPAG--PAGPRGEVGLPGLSGPVGP-PGNPGANGLT 306
Score = 37.7 bits (86), Expect = 0.12
Identities = 42/118 (35%), Positives = 49/118 (41%), Gaps = 22/118 (18%)
Query: 951 EEMFGGGAADDY---GKAGPPEDEG-DPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETP 1006
EE G A D G+ GPP G D + G PPGPP P GP G A +
Sbjct: 27 EETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPG--PPGPPGLGGNFAAQYDGK 84
Query: 1007 GLGLDPNKPPELPSTVNAEPLGLI-QSGPHQAAPPPPPPPPPPPAPASEP-KGGLTSP 1062
G+GL P P+GL+ GP AA P P PA EP + G T P
Sbjct: 85 GVGLGPG------------PMGLMGPRGPPGAA--GAPGPQGFQGPAGEPGEPGQTGP 128
Score = 36.6 bits (83), Expect = 0.26
Identities = 30/102 (29%), Positives = 35/102 (34%), Gaps = 18/102 (17%)
Query: 1412 GPKDTSTPDGPPLAPA----AAVPGPPPLPGLPSANSN------------GTPEPPLLEE 1455
GP+ P GPP PGPP PG P N G L+
Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGP 98
Query: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP 1497
+ PP AP PQ P P +P P A P+ PP
Sbjct: 99 RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAG--ARGPAGPP 138
Score = 33.1 bits (74), Expect = 2.8
Identities = 51/178 (28%), Positives = 60/178 (33%), Gaps = 35/178 (19%)
Query: 1683 PVSAGGSSAPP-PKAPA-------PPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSL 1734
PV A G + P P PA PP P PP + + P PP P
Sbjct: 758 PVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEG 817
Query: 1735 LR-------PVEKEKEKEKVT----RGERPLRGERATSGRQTRPERSLATGQPATSRLPK 1783
LR PV + E V GE+ GE T+G P G P LP
Sbjct: 818 LRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPG 877
Query: 1784 ARPTK-------VKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDER 1834
+R + EP P L AG GPPG+ S GAP E R
Sbjct: 878 SRGERGLPGVAGAVGEPGP------LGIAG--PPGARGPPGAVG-SPGVNGAPGEAGR 926
Score = 32.7 bits (73), Expect = 3.7
Identities = 31/112 (27%), Positives = 36/112 (32%), Gaps = 13/112 (11%)
Query: 1446 GTPEPPLLEEKPPPTPPPAPTPQPQPP------PPPPPPQPALPSPPPLVAPTPSSPPPP 1499
G P PP + + PT PP P P PP + P P+ P PP
Sbjct: 45 GPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGA 104
Query: 1500 PLPPPP-----PPAMPSPPPPPPPAAA--PLAAPPEEPAAPSPEDPELPDTR 1544
P P P P P PA A P P + P P P R
Sbjct: 105 AGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGER 156
Score = 32.0 bits (71), Expect = 6.3
Identities = 31/110 (28%), Positives = 34/110 (30%), Gaps = 7/110 (6%)
Query: 1412 GPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
GP+ S P G + PG GLP NG P + P
Sbjct: 994 GPRGPSGPQG--IRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051
Query: 1471 PPPPPPPPQPA----LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516
P P P PA P V P P P PP P PP PP
Sbjct: 1052 PRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPP 1101
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 113 bits (283), Expect = 2e-24
Identities = 209/795 (26%), Positives = 282/795 (35%), Gaps = 136/795 (17%)
Query: 215 GPAGLGPAQTPPYRPGPPDPPPPPR----------HLPTQFNLLASSSAAAAAAEQSSPQ 264
GPA +GP P PP P R H+ + LL ++ S +
Sbjct: 667 GPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQE 726
Query: 265 LYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSY--PS 322
G APG PP E R IK ++ PP P P L G S+ P
Sbjct: 727 YLLDEGPAPGTPPREARPGRHGHSIKR-----ASVPPVPGKPRQVLPP----GTSHFTPP 777
Query: 323 MGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRP 382
SP G P A +K P+ + R P + G +
Sbjct: 778 QTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRG---FAY 834
Query: 383 IIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA 442
++ P +G G AA G PP P TA P L A A A A
Sbjct: 835 VLPQPV----EGEVGPAAPGPAPPPVP--TAVPTL-CLPPEADAEPGRPKKRAHSLNRYA 887
Query: 443 YSPGQPQ-------GLLGPQAYGQGFGG---------GQAQDLSKAPSYSGGPPQPPSGP 486
S +P+ GP A Q G G ++++++ S++ P + P
Sbjct: 888 ASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPP 947
Query: 487 PPPGLATCQSYSPDQLQGQLYGVQGEPYPGP-AAHSQGLPTASPSLSYSTGHSPALSGHG 545
PPP ++ S + + EP G +Q + + S TG + ++
Sbjct: 948 PPPKRSSSALASANLADEPV--PDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIA 1005
Query: 546 GGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
SS+GGGG A+ + PP P SP PG+ +++VLAS
Sbjct: 1006 AMLELSSIGGGGRAA--------RRPPEGHPTPRPASP-EPGR-VATVLASVKH------ 1049
Query: 606 GSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQ-APSPPRTSGADGLVGE 664
+ GPGG R + LL A P S G E
Sbjct: 1050 -----------------KEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVE 1092
Query: 665 DGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAAL-ELGLG 723
DG + G S G G G P LAK + L+ IR + E L E
Sbjct: 1093 DGTG-RQRPRGPSKGEAGVEGPP--LAKVEASAT-LKRRIRAKQNQQENVKFILTESDTV 1148
Query: 724 RLKEKKKGPERGGETPEGLATSVVHYGAGA-KELGAFLQKSPP---PPPPTAQSTQ---- 775
+ + K K E G E P L SV H G G + A Q PP PPPP A+
Sbjct: 1149 KRRPKAKEREAGPEPPPPL--SVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLA 1206
Query: 776 -----PTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD 830
P P G EA P P V P P L V SP+P++ KV P
Sbjct: 1207 HLPPLPPPEG---EARKPAKPPV--SPKPVLTQPVPKLQGSPTPTSKKV------PLPGP 1255
Query: 831 GAPQ------PPPPPPPPPP-----PMPLQLEAHLRSHGLEPA-APSPRLRPEESLDPPG 878
G+P+ PPP P PP P P++ A L S P+ APSP +P +L P
Sbjct: 1256 GSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPP 1315
Query: 879 AMQELLGALEPLPPAPGDTGV----GPPNSEGKDPAGAYRSPSP-----QGTKAPRFVPL 929
LGA PP+PG + PP + A A P+P G A + +
Sbjct: 1316 GTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEE 1375
Query: 930 TSICFPDSLLQDEER 944
TS C +L EE+
Sbjct: 1376 TSACLAAALQAVEEK 1390
Score = 87.8 bits (216), Expect = 1e-16
Identities = 197/821 (23%), Positives = 263/821 (32%), Gaps = 130/821 (15%)
Query: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSV---LSHAPSPSPSASK 818
+SPPPP PT Q ++ D P ++ P+ SH P + ++
Sbjct: 632 ESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTR 691
Query: 819 VGVHLLEPATRDGAPQPPPPPPPPPPPMPL-QLEAHLRSHGLEPAAPSPRLRP------- 870
L A + Q PP P P+ + + +L G P P RP
Sbjct: 692 QDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSI 751
Query: 871 -EESLDP-PGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRF-V 927
S+ P PG +++L PG + PP + K G SPQ P
Sbjct: 752 KRASVPPVPGKPRQVL--------PPGTSHFTPPQTPTKTRPG-----SPQALGGPHGPA 798
Query: 928 PLTSICFPD-SLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKA-GAGPPPGPP 985
P T+ P LL ER P Y P E E P A G PPP P
Sbjct: 799 PATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPT 858
Query: 986 AYD-----PYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
A P PGR ++P V A +GP+
Sbjct: 859 AVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAA------AGPYATVQR 912
Query: 1041 PPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYE 1100
APA K S F + +P+K + PP PK+ +
Sbjct: 913 RVGRSHSVRAPAGADKNVNRSQSF-AVRPRK------------KGPPPPPPKRSSSALAS 959
Query: 1101 FE-ADEDKADV-PAD----IRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRR 1154
ADE D P D +R RR DL S + A S + G R
Sbjct: 960 ANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRA 1019
Query: 1155 RGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEA 1214
R P +G P PR P + P +T K G G E
Sbjct: 1020 ARRPP-----EGHPTPR----------PASPEPGRVATVLASVKHKEAIGPGG-----EV 1059
Query: 1215 GGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAIS-GTDHNSLDSSLTREKIEAKIKEVEEK 1273
R P+ L+ + G G G + GT R + +K + E
Sbjct: 1060 VNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQ-------RPRGPSKGEAGVEG 1112
Query: 1274 QPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVP 1333
P K A+ +++ + + LT S P R P+PP +V
Sbjct: 1113 PPLAKVEASATLKRRIRAKQNQQENVKFILTE--SDTVKRRPKAKEREAGPEPPPPLSVY 1170
Query: 1334 HPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRD 1393
H G G SE G P E +L LP E ++ +
Sbjct: 1171 HN------GTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAK- 1223
Query: 1394 LQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG---PPPLPGLPSAN-SNGTPE 1449
PP++ PK T P L + P P PG P ++GTP
Sbjct: 1224 --------------PPVS-PKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPP 1268
Query: 1450 PPLLEEKPPPTPPP-------------APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSP 1496
P + PPPT P P+P P P PP P PP + +P+ P
Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKP 1328
Query: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537
P P P PA PP AAA AAPP P SP D
Sbjct: 1329 PSPGAPALHVPA--KPPRAAAAAAAAAAAPPAPPEGASPGD 1367
Score = 73.6 bits (179), Expect = 2e-12
Identities = 71/248 (28%), Positives = 91/248 (36%), Gaps = 76/248 (30%)
Query: 1388 VAKNRDLQESISSAISALDDP---PLAGPKDTSTPDGPPLA------------PAAAVPG 1432
+ ++ QE++ ++ D P A ++ PPL+ PA+ G
Sbjct: 1128 IRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAG 1187
Query: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTP----PPAPTPQPQ---PPPPPPPPQPALPSP 1485
PP LP P PP E PPPT PP P P+ + P PP P+P L P
Sbjct: 1188 PPELP----------PPPPPAE--PPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQP 1235
Query: 1486 PPLV--APTPSSPPPPPLPPP-----------PPPAMPSPPPP----------------- 1515
P + +PTP+S P LP P PPP P PPPP
Sbjct: 1236 VPKLQGSPTPTSKKVP-LPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGS 1294
Query: 1516 --PPPAAAPLAAPPEEPAAP---------SPEDPELPDTRPLHLAKKQETAAVCGETDEE 1564
P PA +P PP A P SP P P LH+ K AA
Sbjct: 1295 AGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAA 1354
Query: 1565 AGESGGEG 1572
A + EG
Sbjct: 1355 APPAPPEG 1362
Score = 71.2 bits (173), Expect = 9e-12
Identities = 61/192 (31%), Positives = 69/192 (35%), Gaps = 31/192 (16%)
Query: 1408 PPLAGPKDTSTPDGPPLAPA---AAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464
PP A P T PPL P A P PP+ P T P L+ P PT
Sbjct: 1195 PPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVL----TQPVPKLQGSPTPTSKKV 1250
Query: 1465 PTPQP----------QPPP--PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
P P P PPP P PPP P P P VA PS P P P PA P
Sbjct: 1251 PLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPS--PAPSPARQPP 1308
Query: 1513 -----PPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGE 1567
PP PP+ A P P AP+ P P A AA G
Sbjct: 1309 AALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPR-----AAAAAAAAAAAPPAPPEGA 1363
Query: 1568 SGGEGIFRERDE 1579
S G+ ++ +E
Sbjct: 1364 SPGDSARQKLEE 1375
Score = 64.3 bits (155), Expect = 1e-09
Identities = 160/735 (21%), Positives = 217/735 (29%), Gaps = 176/735 (23%)
Query: 1178 PLEV-PTTAGPASASTPTDGAKKPR-----GRGRGRGRKAEEAGGTRLEPLKPL-KIKLS 1230
P EV PTT P+S PT A + GR R E G P P+ + +
Sbjct: 668 PAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEY 727
Query: 1231 VPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLK 1290
+ G GT +A G +S+ A + V K ++ L
Sbjct: 728 LLDEGPAPGTPPREARPGRHGHSIK--------RASVPPVPGKPRQV-----------LP 768
Query: 1291 SGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQP-PATPAVPH-----PPPSGAFGLG 1344
G H TPP +P K+ P S A G P PAT V PP
Sbjct: 769 PGTSH-------FTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPR 821
Query: 1345 GALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA 1404
++ G P P + E A + +A+
Sbjct: 822 SLPQSPTHRGFAYVLPQPV-------------------EGEVGPAAPGPAPPPVPTAVPT 862
Query: 1405 LDDPPLAG-----PKDTS-------TPDGPP-----LAPAAAVPGPPPLPGLPSANSNGT 1447
L PP A PK + D P L PAAA GP S+
Sbjct: 863 LCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAA--GPYATVQRRVGRSHSV 920
Query: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQP--ALPSPPPLVAPTPSSPPPPPL---- 1501
P ++ + A P+ + PPPPPP + AL S P P + P L
Sbjct: 921 RAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVR 980
Query: 1502 -----------------------------------------PPPPPPAMPSPPPPPPPAA 1520
PP P P P P
Sbjct: 981 AQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRV 1040
Query: 1521 APLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEF 1580
A + A + A P + R L + GES G F E
Sbjct: 1041 ATVLASVKHKEAIGPGGEVVNRRRTL----SGPVTGLLATARRGPGESADPGPFVEDGT- 1095
Query: 1581 VIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKN 1640
P + G E PP+ +V+ + K K Q++
Sbjct: 1096 ---GRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQE---------------- 1136
Query: 1641 RYQRLYVKFL----ENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKA 1696
VKF+ + V ++ + P PP+ V +G A PP+
Sbjct: 1137 -----NVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPEL 1191
Query: 1697 PAPPPKPETPEKTTSEKPPEQTPE---TAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERP 1753
P PPP E P + PP PE +PP KP L +PV K + T + P
Sbjct: 1192 PPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVP 1251
Query: 1754 LRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGG 1813
L G G P R P PPP K +K G +
Sbjct: 1252 LPG----------------PGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSA 1295
Query: 1814 GPPGSSSDSESSPGA 1828
GP + S + P A
Sbjct: 1296 GPSPAPSPARQPPAA 1310
Score = 60.1 bits (144), Expect = 2e-08
Identities = 69/264 (26%), Positives = 90/264 (34%), Gaps = 51/264 (19%)
Query: 1311 KSVPPSVPARGLQPQPPA--TPAVPHPPPSGAFG---LGGALEAAESEGLGLGCPSPCKR 1365
+ P S+ ++ PP TPA P F L L+AA + P+
Sbjct: 620 RKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTG------PAEVGP 673
Query: 1366 LDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLA 1425
E+ +L P ++ ++ S+ +SS+ L D P GP + L
Sbjct: 674 TTEKPSSHLPPTPRATTRQDSSLGGRA---RHMSSSQELLGDGP-PGPSSPMSRSQEYLL 729
Query: 1426 PAAAVPGPPPLPGLPSANSNGT------PEPPLLEEKPPP-----TPPPAPT------PQ 1468
PG PP P + + P P + PP TPP PT PQ
Sbjct: 730 DEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQ 789
Query: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP------------------PAMP 1510
P P P A P P + P P P P P PA P
Sbjct: 790 ALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAP 849
Query: 1511 SPPPPPPPAAAP-LAAPPEEPAAP 1533
P PPP P A P L PPE A P
Sbjct: 850 GPAPPPVPTAVPTLCLPPEADAEP 873
Score = 54.3 bits (129), Expect = 1e-06
Identities = 199/893 (22%), Positives = 276/893 (30%), Gaps = 197/893 (22%)
Query: 468 DLSKAP--SYSGGP-----PQ---------PPSGPPPPGLATCQSYS---------PDQL 502
+L KA Y GGP PQ PP PP P A CQS D+L
Sbjct: 604 ELQKAEYAKYEGGPLRRKAPQSLEVMAIESPP--PPEPTPADCQSPKMTTFQDSELSDEL 661
Query: 503 QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSS--LGGGGEAS 560
Q + G E P S LP P+ +T +L G S LG G
Sbjct: 662 QAAMTG-PAEVGPTTEKPSSHLP---PTPRATTRQDSSLGGRARHMSSSQELLGDGPPGP 717
Query: 561 PSHIIRP----LQSPPATGRPPGVGSPGAPGKYLSSVLASAP-------FLAPPGAGSYA 609
S + R L PA G PP PG G + AS P + PPG +
Sbjct: 718 SSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKR--ASVPPVPGKPRQVLPPGTSHFT 775
Query: 610 AGAGGYKGKGDGSELLAGPGGP---------------PAERTEDEEFLIQ--------HL 646
K + + L GP GP P ER L Q ++
Sbjct: 776 PPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYV 835
Query: 647 LQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP---------YELAKEDPQR 697
L P A A L A PG P Y + +P+R
Sbjct: 836 LPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPER 895
Query: 698 YHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELG 757
L A+ AT +G G ++ + A
Sbjct: 896 DELL----VPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRP----------- 940
Query: 758 AFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLL---------PSVLSH 808
+K PPPPPP S+ L A D P+ P LL +
Sbjct: 941 --RKKGPPPPPPKRSSSA------LASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGS 992
Query: 809 APSPSPSASKVGVHLLEPATRDG----APQPPP--PPPPPPPPMPLQLEAHLRSHGLEPA 862
+ S + K +LE ++ G A +PP P P P P P ++ L S
Sbjct: 993 VDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLAS------ 1046
Query: 863 APSPRLRPEESLDPPGAMQE--------LLGALEPLPPAPGDTGVGPPNSEGKDPAGAYR 914
++ +E++ P G + + G L PG++ P E D G R
Sbjct: 1047 -----VKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVE--DGTGRQR 1099
Query: 915 SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDP 974
P +A P + + L+ R+ E + D K P E +
Sbjct: 1100 PRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKERE- 1158
Query: 975 KAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGP 1034
AGP P PP + +G G TV P
Sbjct: 1159 ---AGPEPPPPLSVYH--------NGTG------------------TVRRRPAS------ 1183
Query: 1035 HQAAPPPPPPPPPPP----------APASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRR 1084
QA PP PPPPPP P P+G P PK +L + + +
Sbjct: 1184 EQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQP---VPKLQ 1240
Query: 1085 DPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCP 1144
P T KK+ + P + P P ++ L P G P
Sbjct: 1241 GSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGL-PSGSAGPSP 1299
Query: 1145 -PNPGPDGPRRRGRKPTKAKRDG-----PPRPRGRPRIRPLEVPTTAGPASASTPTDGAK 1198
P+P P + P G PP P G P + P A A+A+
Sbjct: 1300 APSPARQPPAALAKPPGTPPSLGASPAKPPSP-GAPALHVPAKPPRAAAAAAAAAAAPPA 1358
Query: 1199 KPRGRGRGRG--RKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGT 1249
P G G +K EE L+ ++ K+ A +G S+ + +G+
Sbjct: 1359 PPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDA-QGPRDSAAEKSTGS 1410
Score = 53.9 bits (128), Expect = 2e-06
Identities = 131/601 (21%), Positives = 191/601 (31%), Gaps = 102/601 (16%)
Query: 1303 LTPPLSPPKSVPPSV--PARGLQPQPPATPAVPHPPPSGAFGLGGALE--AAESEGLGLG 1358
L ++ P V P+ P+ L P P AT LGG ++ E LG G
Sbjct: 661 LQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDS-------SLGGRARHMSSSQELLGDG 713
Query: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418
P P + + L+ P+ + ++ +I PP+ G
Sbjct: 714 PPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRH------GHSIKRASVPPVPGKPRQVL 767
Query: 1419 PDG-----PPLAPAAAVPGPPPLPGLPSANSNGT----PEPPLLEEKPPPTPPPAPTPQP 1469
P G PP P PG P G P + T P P LL PP P +P P
Sbjct: 768 PPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLL---PPTERPMSPRSLP 824
Query: 1470 QPPPPPPPPQPALPSPPP-LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528
Q P LP P V P P PPP+P P P P A
Sbjct: 825 QSPTHRGFAY-VLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSL 883
Query: 1529 EPAAPSPEDPELPDTR-PLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDI 1587
A S +PE + P G + +G + F +R
Sbjct: 884 NRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPR-- 941
Query: 1588 PSLKLALQTGREPPPIWRVQKA-----LLQKFTPEIKD-----GQRQFCATSNYL----- 1632
+ G PPP R A L + P+ + G R C ++ L
Sbjct: 942 -------KKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVD 994
Query: 1633 -GYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVP------------VRRSGQ 1679
G G K+ L + + + AR+P P P V S +
Sbjct: 995 TGSAGSVKSIAAMLELSSIGGGGR------AARRPPEGHPTPRPASPEPGRVATVLASVK 1048
Query: 1680 AKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE 1739
K + GG + + P T T+ + P E+A P P + RP
Sbjct: 1049 HKEAIGPGGEVVNRRRTLS---GPVTGLLATARRGP---GESADPGPFVEDGTGRQRPRG 1102
Query: 1740 KEK-----EKEKVTRGERPLRGERATSGRQTRPE--RSLATGQPATSRLPKARPTKVKAE 1792
K E + + E +R +Q + E + + T R PKA+ + E
Sbjct: 1103 PSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPE 1162
Query: 1793 PPPK-----------KRKKWLKEAGGNATAGGGPPGSSSDSESS---PGAPSEDERAVPG 1838
PPP +R+ ++AG PP ++ + P P E E P
Sbjct: 1163 PPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPA 1222
Query: 1839 R 1839
+
Sbjct: 1223 K 1223
Score = 45.8 bits (107), Expect = 4e-04
Identities = 160/675 (23%), Positives = 202/675 (29%), Gaps = 113/675 (16%)
Query: 81 SAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSS 140
S G A M+ L GP PGPS+ SQ L G PG
Sbjct: 695 SLGGRARHMSSSQELLGDGP-PGPSSPMSRSQ---------------EYLLDEGPAPG-- 736
Query: 141 TFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVP 200
T P + + H S P PVP PP + H P Q PT
Sbjct: 737 TPPREARPGRHGHSIKRASVP-PVPGKPRQVLPPGTS------------HFTPPQTPTKT 783
Query: 201 SSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQ 260
+ L G PA TP P P + P PR LP S + A
Sbjct: 784 RPGSPQALGGPHGPAPATAKVKPTPQLLP-PTERPMSPRSLP------QSPTHRGFAYVL 836
Query: 261 SSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP--ASAQPPPPPPPAHALQHYL---- 314
P AAPGP PP T + P A A+P P AH+L Y
Sbjct: 837 PQPVEGEVGPAAPGPAPPP-----VPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDS 891
Query: 315 ----------SCGGSYPSMGHRANLACS---PLGG----GEPSPGAGEPSKAGP------ 351
+ G Y ++ R + S P G A P K GP
Sbjct: 892 EPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPK 951
Query: 352 --SGATAGAS-GRATGPEAAGGGG--------------AGGGGGGYRPIIQSPGYKTGKG 394
S A A A+ P+A G AG G ++S
Sbjct: 952 RSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELS 1011
Query: 395 GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYS-----PGQPQ 449
G A RPP T P G A A+ K A G GG+ + G
Sbjct: 1012 SIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVT 1071
Query: 450 GLLGPQAYGQGFGG--GQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLY 507
GLL G G G + GP + +G P LA ++ + + + +
Sbjct: 1072 GLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAK 1131
Query: 508 GVQGEPYPGPAAHSQGLPTASPSLSYSTGHS--PALSGHGGGWGPSSLGGGGE-ASPSHI 564
Q E S + + G P LS + G G E A P +
Sbjct: 1132 QNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPEL 1191
Query: 565 IRPLQSPPATGRPPGVG--SPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGS 622
P PPA P + P P + + A P P G
Sbjct: 1192 --PPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKK 1249
Query: 623 ELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTS-----GADGL-VGEDGAADA-SKGLG 675
L GPG P +R + P PP T+ GL G G + A S
Sbjct: 1250 VPLPGPGSPEVKRAHGTP---PPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQ 1306
Query: 676 GSGGAGGPPGTPYEL 690
PPGTP L
Sbjct: 1307 PPAALAKPPGTPPSL 1321
Score = 34.7 bits (78), Expect = 0.98
Identities = 32/136 (23%), Positives = 49/136 (36%), Gaps = 15/136 (11%)
Query: 397 GAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQA 456
G+++ G + PP + GG + +G A G G G ++ + LL
Sbjct: 362 GSSSSGPSAPP--EEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVKLL---- 415
Query: 457 YGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPG 516
A LS+ GP P+ PP +S P GQ+YG Q
Sbjct: 416 ---------ATVLSQKSVSESGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPPKKLE 466
Query: 517 PAAHSQGLPTASPSLS 532
PA+ + S L+
Sbjct: 467 PASEGKSSEAVSQWLT 482
Score = 33.9 bits (76), Expect = 1.7
Identities = 30/117 (25%), Positives = 40/117 (34%), Gaps = 18/117 (15%)
Query: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETA 1722
A P +PP + + P S G S PA PP P P KPP A
Sbjct: 1300 APSPARQPPAALAKP--PGTPPSLGAS-------PAKPPSPGAPALHVPAKPPRAAAAAA 1350
Query: 1723 MPEPPAPEKPSLLRPVEKEKEKEKVTRG---------ERPLRGERATSGRQTRPERS 1770
P P P + ++K + T E +R E A R + E+S
Sbjct: 1351 AAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKS 1407
Score = 32.3 bits (72), Expect = 4.9
Identities = 43/165 (26%), Positives = 56/165 (33%), Gaps = 32/165 (19%)
Query: 100 PQPGPSASSLLSQFRSPSWQTAMHTPGPTE---LFISGALPGSSTFPSSSALSAYQHPAS 156
P PGP + + +P + P PT + LP S PS + A Q PA+
Sbjct: 1251 PLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA 1310
Query: 157 FGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP 216
P P SL P PP+ G + H + KP +A
Sbjct: 1311 LAKPPGTPP---SLGASPAKPPSPGAPALH--VPAKPPRA------------------AA 1347
Query: 217 AGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQS 261
A A PP P P R L +SA AAA Q+
Sbjct: 1348 AAAAAAAAPPAPPEGASPGDSAR------QKLEETSACLAAALQA 1386
Score = 32.0 bits (71), Expect = 6.3
Identities = 21/72 (29%), Positives = 27/72 (37%), Gaps = 7/72 (9%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPE--TAMPEPP 1727
PP P A PV A P+P P P KPP P + +PP
Sbjct: 1275 PPPPT-----APKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPP 1329
Query: 1728 APEKPSLLRPVE 1739
+P P+L P +
Sbjct: 1330 SPGAPALHVPAK 1341
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 112 bits (279), Expect = 5e-24
Identities = 275/1046 (26%), Positives = 332/1046 (31%), Gaps = 215/1046 (20%)
Query: 114 RSPSWQTA-MHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSR--------PFPV 164
RSP Q + +H P E PG S+L A+ G R P +
Sbjct: 246 RSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVL 305
Query: 165 PSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQT 224
+ ++ PP GL+ P + Q P ER G G AGL
Sbjct: 306 EPGMLVEGPPGPEGPAGLIGPPGI------QGNPGPVGDPGER----GPPGRAGL----- 350
Query: 225 PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQ--LYNFSGAAPGPPPPERAL 282
P G P PP LP +F AA+++ Q L A GPP P
Sbjct: 351 -PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP---- 405
Query: 283 PRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPG 342
+ + RP P GS G +L P G P
Sbjct: 406 ------MGYTGRPGPLGQP----------------GSPGLKGESGDLG--PQGPRGPQGL 441
Query: 343 AGEPSKAGPSGATA--GASGRATGPEAAGGGGAGG-----------GGGGYRPIIQSPGY 389
G P KAG G GA G P G G G G G + + PG
Sbjct: 442 TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE 501
Query: 390 KTGKGGYG----------AAAGGATRPP-PPRSTATPKCQSLGGPAAAYATGKASGAGGA 438
+G G + G P PP P + + GP + G G
Sbjct: 502 DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561
Query: 439 GGQAYSPGQPQGLLGPQ-AYG-QGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQS 496
GQ +PG QGL GPQ A G G G Q + S GPP P PPG T +
Sbjct: 562 PGQQGTPGT-QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG--TKGN 618
Query: 497 YSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHS--------PALSGHGGGW 548
P QG L YPGP +G+ + GH P G G
Sbjct: 619 QGPSGPQGPL------GYPGP----RGVKGVD-GIRGLKGHKGEKGEDGFPGFKGDIGVK 667
Query: 549 G-------PSSLGGGGEASPSHIIRPLQSPPATGRPPGV----------GSPGAPGKYLS 591
G P S G G P P P PPG+ G PG PG+
Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG----PPGLMGEKGKLGVPGLPGYPGR--Q 721
Query: 592 SVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPS 651
S F PGA S GA G GK G GP GP +R +
Sbjct: 722 GPKGSLGFPGFPGA-SGEKGARGLSGKS-GPRGERGPTGPRGQRGP------RGATGKSG 773
Query: 652 PPRTSGADGLVGEDG--AADASKGLGGSGGAGGPPGTPYE--LAKEDPQRYHLQSVIRTS 707
TSG DG G G +G G G GPPG P + L QR + +T
Sbjct: 774 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 833
Query: 708 ASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP 767
G G E ERG P G G KE G PP
Sbjct: 834 PPGPPGVVGPQ----GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKE-GTKGDPGPPGA 888
Query: 768 P----PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHL 823
P P P GL AGGP L P P P P+ S + G
Sbjct: 889 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP----------PGPAGSPGERG--- 935
Query: 824 LEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEES--LDPPG--A 879
A G P PP P P P P A + P E + P G
Sbjct: 936 ---AAGSGGPIGPPGRPGPQGP---------------PGAAGEKGVPGEKGPIGPTGRDG 977
Query: 880 MQELLGALEPLPPA-----PGDTG-VGPPNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSI 932
+Q +G P P GD G VG P +G K G + P P G P P +
Sbjct: 978 VQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1037
Query: 933 CFPDSLLQDEERSFFPTMEEMFGG-----GAADDYGKAGPPEDEGDPKAGAGP--PPGPP 985
+ + + F +E G G G GP ++G+ GP PPGPP
Sbjct: 1038 ADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET-GDVGPMGPPGPP 1096
Query: 986 AYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAP------ 1039
P GP P A GP+ P G+ PP IQ P P
Sbjct: 1097 G--PRGPAGPNGAD--GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1152
Query: 1040 ------PPPPPPPPPPAPASE--PKG 1057
P P PP P P + PKG
Sbjct: 1153 KGESGQPGEPGPPGPKGPTGDDGPKG 1178
Score = 102 bits (254), Expect = 4e-21
Identities = 193/742 (26%), Positives = 235/742 (31%), Gaps = 125/742 (16%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G G GL Q P PGP PP PP F G
Sbjct: 785 GPPGERGLPGPQGPNGFPGPKGPPGPP-------------GKDGLPGHPGQRGEVGFQGK 831
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
GPP P + Q + P PP PP G+ G +
Sbjct: 832 T-GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ-----GLPGTAGKEGTK----- 880
Query: 332 SPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKT 391
G+P P G P K GP+G G G P AGG G G G P PG
Sbjct: 881 -----GDPGP-PGAPGKDGPAG-LRGFPGERGLPGTAGGPGLKGNEGPSGP----PGPAG 929
Query: 392 GKGGYGAAAGGATRPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQ-- 447
G GAA G PP P P G +G G G PG
Sbjct: 930 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 989
Query: 448 PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP---PGLATCQSYSPDQLQG 504
P G+ G +G G Q +K GPP PP P PG A +
Sbjct: 990 PPGVAGEDG-DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1048
Query: 505 QLYGVQGEP-------YPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGG 557
+G +G+ PGP QGLP S G G GP +G G
Sbjct: 1049 GHFGAKGDEGTRGFNGPPGPIG-LQGLPGPSGE-----------KGETGDVGP--MGPPG 1094
Query: 558 EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG 617
P P + G P GVG+ G PG+ + +P + G G KG
Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1154
Query: 618 KGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA-----ADASK 672
+ G GP GP +D + P P G G G+DGA D
Sbjct: 1155 E-SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR--TSASLDEGATAALELGLGRLKEKKK 730
G GS G G G P L K P + A D GA A G+
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA----PGKTGPVGP 1269
Query: 731 GPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP--PPTAQSTQPTPHGLLLEAGGP 788
G P+GL G + GA Q PP P PP + G E G P
Sbjct: 1270 AGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA-GAKGEKGHP 1327
Query: 789 DL-PLVLPP-----------PPPQLLPSVLSHAPSPSPSA-----------SKVGVHLLE 825
L L+ PP P PQ P P S G +
Sbjct: 1328 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1387
Query: 826 PATRDGAP------QPPPPPPPPP----PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
AT G P Q PP P PP P+P+Q+ R + RL E+
Sbjct: 1388 GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR-----SVDGSRLMQEDEAI 1442
Query: 876 P-------PGAMQELLGALEPL 890
P PG ++E+ G+L+ L
Sbjct: 1443 PTGGAPGSPGGLEEIFGSLDSL 1464
Score = 77.4 bits (189), Expect = 1e-13
Identities = 270/1148 (23%), Positives = 337/1148 (29%), Gaps = 249/1148 (21%)
Query: 445 PGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPG-------------- 490
P P GL+GP QG G + P G P P PPG
Sbjct: 317 PEGPAGLIGPPGI-QGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 375
Query: 491 -----LATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHG 545
+A ++ + LQ ++G P P G P P SP L G
Sbjct: 376 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG-PLGQPG-------SPGLKGES 427
Query: 546 GGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGA 605
G GP G P + P GR G+ G PG V F PG
Sbjct: 428 GDLGPQ-----GPRGPQGLTGPPGKAGRRGRAGADGARGMPGD--PGVKGDRGFDGLPGL 480
Query: 606 GSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHL---------LQAPSPPRTS 656
G G++G G++ L GP G ER +D E + L L PP
Sbjct: 481 ----PGEKGHRGD-TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP 535
Query: 657 GADGLVGEDGAADASKGLGGSGGAGGPPG---TPYELAKEDPQRYHLQSVIRTSASLDEG 713
G G+ G DG KG G G GPPG TP PQ G
Sbjct: 536 GPPGVRGMDGP-QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ----------------G 578
Query: 714 ATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQS 773
A +KGP+ P G+ S G KE + + P P
Sbjct: 579 AIGP---------HGEKGPQGKPGLP-GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 628
Query: 774 TQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATR-DGA 832
P P G+ G L P +VGV P +R +
Sbjct: 629 GYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI-GVKGDRGEVGV----PGSRGEDG 683
Query: 833 PQPPP----PPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALE 888
P+ P P P PP + + L GL P P R P+ SL PG
Sbjct: 684 PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL-PGYPG-RQGPKGSLGFPG---------- 731
Query: 889 PLPPAPGDTGVGPPNSEGKDPAGAYRSPS-PQGTKAPRFVPLTSICFPDSLLQDEERSFF 947
P A G+ G GK R P+ P+G + PR S S
Sbjct: 732 -FPGASGEKGAR--GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS---------- 778
Query: 948 PTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPYCPGRASGAGPET 1005
G G G+ G P +G P GP PPGPP D P PG+ G +
Sbjct: 779 ------GGDGPHGPPGERGLPGPQG-PNGFPGPKGPPGPPGKDGL-PGHPGQRGEVGFQ- 829
Query: 1006 PGLGLDPNKPPELPSTVNAEPLGLI-QSGP--HQAAPPPPPPPPPPPAPASEPKGGLTSP 1062
PP P V P G ++GP + P PP PP P + K G
Sbjct: 830 -----GKTGPPGPPGVVG--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 882
Query: 1063 IFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLN----P 1118
PP K A F + L P
Sbjct: 883 ---------------------PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGP 921
Query: 1119 RRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIR- 1177
P S R A G I P PGP GP + GP P GR ++
Sbjct: 922 SGPPGPAGSPGERGAAGSGGPIG-PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 980
Query: 1178 PLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEG 1237
P+ +P AGP + DG K G +G K + P P+ P G
Sbjct: 981 PVGLPGPAGPPGVAGE-DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG-----PVGQPG 1034
Query: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPP 1297
+ G+ + + K E GF G P
Sbjct: 1035 AAGADGEPGARGPQGHFGA----------------KGDEGTRGFNGPPGPIGLQGLPGPS 1078
Query: 1298 --LYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGL 1355
+ G P+ PP P PA P P PP G LG E E
Sbjct: 1079 GEKGETGDVGPMGPPGPPGPRGPAG------PNGADGPQGPPGGVGNLGPPGEKGEPGES 1132
Query: 1356 GLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKD 1415
G SP ++ P + K Q +P GPK
Sbjct: 1133 G----SP----------GIQGEPGVKGPRGERGEKGESGQPG---------EPGPPGPKG 1169
Query: 1416 TSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475
+ DGP PGP PG P PP P+ Q
Sbjct: 1170 PTGDDGPK-----GNPGPVGFPG-------------------DPGPPGEGGPRGQDGAKG 1205
Query: 1476 PPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMP---------SPPPPPPPAAAPLAAP 1526
+ P P PT + PP PL P P P AP
Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265
Query: 1527 PEEPAAPS 1534
P PA P+
Sbjct: 1266 PVGPAGPA 1273
Score = 47.8 bits (112), Expect = 1e-04
Identities = 107/453 (23%), Positives = 132/453 (29%), Gaps = 75/453 (16%)
Query: 1408 PPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLP-SANSNGTPEPPLLEEKPPPTPPPAP 1465
P + GP+ + GP PGPP GLP +A GT P PP P
Sbjct: 838 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP-----GPPGAPGKD 892
Query: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP------------PPAMPSPP 1513
P P P P L S PP P P PP P P
Sbjct: 893 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 952
Query: 1514 PPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGI 1573
PP A + P P+ D P+ L V GE D + GE G G
Sbjct: 953 GPPGAAGEKGVPGEKGPIGPTGRDGV---QGPVGLPGPAGPPGVAGE-DGDKGEVGDPG- 1007
Query: 1574 FRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLG 1633
++ + E P P PI V + DG+ + G
Sbjct: 1008 --QKGTKGNKGEHGPP--------GPPGPIGPVGQP-----GAAGADGEPGARGPQGHFG 1052
Query: 1634 YFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPP 1693
GD R ++ PP P+ G G +
Sbjct: 1053 AKGDEGTR------------------------GFNGPPGPIGLQGLPGPSGEKGETGDVG 1088
Query: 1694 PKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERP 1753
P P PP P P P+ P P EK + E +G R
Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148
Query: 1754 LRGERATSGRQTRPERSLATGQPATSRLPKARPTKV--KAEPPPKKRKKWLKEAGGNATA 1811
RGE+ SG+ P G P PK P V +P P GG
Sbjct: 1149 ERGEKGESGQPGEPGPPGPKG-PTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQ 1200
Query: 1812 GGGPPGSSSDSE-SSPGAPS-EDERAVPGRLLK 1842
G D E PG+P E PG L K
Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1233
Score = 46.2 bits (108), Expect = 3e-04
Identities = 61/237 (25%), Positives = 78/237 (32%), Gaps = 32/237 (13%)
Query: 1411 AGPKDTSTPDG-------------PPLAPAAAVPGPPPLPGLPSANSNGTPE-----PPL 1452
AGP PDG P A PGP PGLP + + P L
Sbjct: 1270 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1329
Query: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPPAMPS 1511
+ PP + P P P Q P P P PP P P P A +
Sbjct: 1330 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA 1389
Query: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE-----TDEEAG 1566
P P + PP P P LP P + + + + E T G
Sbjct: 1390 TGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPG 1449
Query: 1567 ESGG-EGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
GG E IF D E+I ++ TG + P Q L+ PE+ DG+
Sbjct: 1450 SPGGLEEIFGSLDSL---REEIEQMR--RPTGTQDSPARTCQD--LKLCHPELPDGE 1499
Score = 41.2 bits (95), Expect = 0.010
Identities = 46/167 (27%), Positives = 51/167 (30%), Gaps = 36/167 (21%)
Query: 1407 DPPLAGPKDTSTPDGPPLAPA----AAVPGPPPLPGLPSANS----------------NG 1446
DP G K GPP P PG G P A NG
Sbjct: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1064
Query: 1447 TPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPP--PPPLPPP 1504
P P L+ P P+ T P PP PP P P+ P A P PP L PP
Sbjct: 1065 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN-GADGPQGPPGGVGNLGPP 1123
Query: 1505 PPPAMPSPPPPP-----PPAAAPL--------AAPPEEPAAPSPEDP 1538
P P P P + P EP P P+ P
Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGP 1170
Score = 40.0 bits (92), Expect = 0.023
Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 21/136 (15%)
Query: 1411 AGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS-NGTPEPPLLEEKPPPTPPPA---PT 1466
+G K TS DGP GPP GLP NG P P K PP PP P
Sbjct: 772 SGAKGTSGGDGPH--------GPPGERGLPGPQGPNGFPGP-----KGPPGPPGKDGLPG 818
Query: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP----PPPPAAAP 1522
Q + P PP +V P ++ P+ P P PP P
Sbjct: 819 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEG 878
Query: 1523 LAAPPEEPAAPSPEDP 1538
P P AP + P
Sbjct: 879 TKGDPGPPGAPGKDGP 894
Score = 37.4 bits (85), Expect = 0.15
Identities = 47/171 (27%), Positives = 61/171 (35%), Gaps = 14/171 (8%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P + G +P G P PP P+ E P E P PP P
Sbjct: 807 PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPGP 864
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
L P KE K G G+ +G + P G P T+ P + +
Sbjct: 865 PGEQGL-PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE---RGLPGTAGGPGLKGNEG 920
Query: 1790 KAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSDSESSPGAPSEDERAVPG 1838
+ PP + A G +GG GPPG + PGA E+ VPG
Sbjct: 921 PSGPPGPAGSPGERGAAG---SGGPIGPPGRPG-PQGPPGAAG--EKGVPG 965
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 111 bits (278), Expect = 6e-24
Identities = 268/1016 (26%), Positives = 325/1016 (31%), Gaps = 214/1016 (21%)
Query: 143 PSSSALSAYQHPASFGSR--------PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS 194
P+ SA +A+ A+ G R P + + ++ PP GL+ P +
Sbjct: 362 PALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI------ 415
Query: 195 QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAA 254
Q P ER G G AGL P G P PP LP +F
Sbjct: 416 QGNPGPVGDPGER----GPPGRAGL------PGSDGAPGPPGTSLMLPFRFGSGGGDKGP 465
Query: 255 AAAAEQSSPQ--LYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQH 312
AA+++ Q L A GPP P + + RP P
Sbjct: 466 VVAAQEAQAQAILQQARLALRGPPGP----------MGYTGRPGPLGQP----------- 504
Query: 313 YLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--GASGRATGPEAAGG 370
GS G +L P G P G P KAG G GA G P G
Sbjct: 505 -----GSPGLKGESGDLG--PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 557
Query: 371 GGAGG-----------GGGGYRPIIQSPGYKTGKGGYG----------AAAGGATRPP-P 408
G G G G + + PG +G G + G P P
Sbjct: 558 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 617
Query: 409 PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQ-AYG-QGFGGGQA 466
P P + + GP + G G GQ +PG QGL GPQ A G G G Q
Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT-QGLPGPQGAIGPHGEKGPQG 676
Query: 467 QDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPT 526
+ S GPP P PPG T + P QG L YPGP +G+
Sbjct: 677 KPGLPGMPGSDGPPGHPGKEGPPG--TKGNQGPSGPQGPL------GYPGP----RGVKG 724
Query: 527 ASPSLSYSTGHS--------PALSGHGGGWG-------PSSLGGGGEASPSHIIRPLQSP 571
+ GH P G G G P S G G P P P
Sbjct: 725 VD-GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 783
Query: 572 PATGRPPGV----------GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDG 621
PPG+ G PG PG+ S F PGA S GA G GK G
Sbjct: 784 G----PPGLMGEKGKLGVPGLPGYPGR--QGPKGSLGFPGFPGA-SGEKGARGLSGKS-G 835
Query: 622 SELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG--AADASKGLGGSGG 679
GP GP +R + TSG DG G G +G G G
Sbjct: 836 PRGERGPTGPRGQRGP------RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 889
Query: 680 AGGPPGTPYE--LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGE 737
GPPG P + L QR + +T G G E ERG
Sbjct: 890 PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ----GAAGETGPMGERGHP 945
Query: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPP----PTAQSTQPTPHGLLLEAGGPDLPLV 793
P G G KE G PP P P P GL AGGP L
Sbjct: 946 GPPGPPGEQGLPGTAGKE-GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004
Query: 794 LPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAH 853
P P P P+ S + G A G P PP P P P
Sbjct: 1005 EGPSGP----------PGPAGSPGERG------AAGSGGPIGPPGRPGPQGP-------- 1040
Query: 854 LRSHGLEPAAPSPRLRPEES--LDPPG--AMQELLGALEPLPPA-----PGDTG-VGPPN 903
P A + P E + P G +Q +G P P GD G VG P
Sbjct: 1041 -------PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPG 1093
Query: 904 SEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGG-----G 957
+G K G + P P G P P + + + + F +E G G
Sbjct: 1094 QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1153
Query: 958 AADDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKP 1015
G GP ++G+ GP PPGPP P GP P A GP+ P G+ P
Sbjct: 1154 PIGLQGLPGPSGEKGET-GDVGPMGPPGPPG--PRGPAGPNGAD--GPQGPPGGVGNLGP 1208
Query: 1016 PELPSTVNAEPLGLIQSGPHQAAP------------PPPPPPPPPPAPASE--PKG 1057
P IQ P P P P PP P P + PKG
Sbjct: 1209 PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1264
Score = 102 bits (254), Expect = 4e-21
Identities = 193/742 (26%), Positives = 235/742 (31%), Gaps = 125/742 (16%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G G GL Q P PGP PP PP F G
Sbjct: 871 GPPGERGLPGPQGPNGFPGPKGPPGPP-------------GKDGLPGHPGQRGEVGFQGK 917
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
GPP P + Q + P PP PP G+ G +
Sbjct: 918 T-GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ-----GLPGTAGKEGTK----- 966
Query: 332 SPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKT 391
G+P P G P K GP+G G G P AGG G G G P PG
Sbjct: 967 -----GDPGP-PGAPGKDGPAG-LRGFPGERGLPGTAGGPGLKGNEGPSGP----PGPAG 1015
Query: 392 GKGGYGAAAGGATRPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQ-- 447
G GAA G PP P P G +G G G PG
Sbjct: 1016 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 1075
Query: 448 PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP---PGLATCQSYSPDQLQG 504
P G+ G +G G Q +K GPP PP P PG A +
Sbjct: 1076 PPGVAGEDG-DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1134
Query: 505 QLYGVQGEP-------YPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGG 557
+G +G+ PGP QGLP S G G GP +G G
Sbjct: 1135 GHFGAKGDEGTRGFNGPPGPIG-LQGLPGPSGE-----------KGETGDVGP--MGPPG 1180
Query: 558 EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG 617
P P + G P GVG+ G PG+ + +P + G G KG
Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1240
Query: 618 KGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA-----ADASK 672
+ G GP GP +D + P P G G G+DGA D
Sbjct: 1241 E-SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR--TSASLDEGATAALELGLGRLKEKKK 730
G GS G G G P L K P + A D GA A G+
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA----PGKTGPVGP 1355
Query: 731 GPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP--PPTAQSTQPTPHGLLLEAGGP 788
G P+GL G + GA Q PP P PP + G E G P
Sbjct: 1356 AGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA-GAKGEKGHP 1413
Query: 789 DL-PLVLPP-----------PPPQLLPSVLSHAPSPSPSA-----------SKVGVHLLE 825
L L+ PP P PQ P P S G +
Sbjct: 1414 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1473
Query: 826 PATRDGAP------QPPPPPPPPP----PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
AT G P Q PP P PP P+P+Q+ R + RL E+
Sbjct: 1474 GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR-----SVDGSRLMQEDEAI 1528
Query: 876 P-------PGAMQELLGALEPL 890
P PG ++E+ G+L+ L
Sbjct: 1529 PTGGAPGSPGGLEEIFGSLDSL 1550
Score = 76.3 bits (186), Expect = 3e-13
Identities = 296/1237 (23%), Positives = 381/1237 (30%), Gaps = 237/1237 (19%)
Query: 441 QAYSPGQPQGLLGPQAYGQGFGGGQAQD------LSKAPSYSGGPPQPPSGPP------- 487
+ Y G GP Y G+G ++ LS ++SG P G
Sbjct: 330 EEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPA 389
Query: 488 --PPGLATCQSYSPDQLQGQLY--GVQGEPYP-------GPAAHSQGLPTA--SPSLSYS 534
PG+ P+ G + G+QG P P GP + GLP + +P +
Sbjct: 390 VLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-GLPGSDGAPGPPGT 448
Query: 535 TGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP----LQSPPA----TGRPPGVGSPGAP 586
+ P G GGG + EA I++ L+ PP TGRP +G PG+P
Sbjct: 449 SLMLPFRFGSGGG-DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSP 507
Query: 587 G-KYLSSVL------ASAPFLAPPGAGSY--AAGAGGYKG-KGD----GSELLAGPGGPP 632
G K S L PPG AGA G +G GD G G G P
Sbjct: 508 GLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLP 567
Query: 633 AERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADAS--KGLGGSGGAGGPPGTPYEL 690
E+ + Q L P G DG +G G S +GL G G G PG P
Sbjct: 568 GEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVR 627
Query: 691 AKEDPQ----RYHLQSVIRTSASLDEGATAALELGLGRL-KEKKKGPERGGETPEGLATS 745
+ PQ Q T L G + +KGP+ P G+ S
Sbjct: 628 GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP-GMPGS 686
Query: 746 VVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSV 805
G KE + + P P P P G+ G L P
Sbjct: 687 DGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGF 746
Query: 806 LSHAPSPSPSASKVGVHLLEPATR-DGAPQPPP----PPPPPPPPMPLQLEAHLRSHGLE 860
+VGV P +R + P+ P P P PP + + L GL
Sbjct: 747 KGDI-GVKGDRGEVGV----PGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGL- 800
Query: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV-GPPNSEGKDPAGAYRSPSPQ 919
P P R P+ SL PG P A G+ G G G P G P+
Sbjct: 801 PGYPG-RQGPKGSLGFPG-----------FPGASGEKGARGLSGKSG--PRGERGPTGPR 846
Query: 920 GTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEG-----DP 974
G + PR + G + G GPP + G P
Sbjct: 847 GQRGPR----------------------GATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884
Query: 975 KAGAGP--PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI-Q 1031
GP PPGPP D P PG+ G + PP P V P G +
Sbjct: 885 NGFPGPKGPPGPPGKDGL-PGHPGQRGEVGFQ------GKTGPPGPPGVVG--PQGAAGE 935
Query: 1032 SGP--HQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
+GP + P PP PP P + K G PP
Sbjct: 936 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD---------------------PGPPGA 974
Query: 1090 TPKKLYAQEYEFEADEDKADVPADIRL----NPRRLPDLVSSCRSRPALSPLGDIDFCPP 1145
K A F + L P P S R A G I P
Sbjct: 975 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIG-PPG 1033
Query: 1146 NPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIR-PLEVPTTAGPASASTPTDGAKKPRGRG 1204
PGP GP + GP P GR ++ P+ +P AGP + DG K G
Sbjct: 1034 RPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA-GEDGDKGEVGDP 1092
Query: 1205 RGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIE 1264
+G K + P P+ P G + G+ + +
Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIG-----PVGQPGAAGADGEPGARGPQGHFGA-------- 1139
Query: 1265 AKIKEVEEKQPEMKSGFMASFLDFLKSGKRHP--PLYQAGLTPPLSPPKSVPPSVPARGL 1322
K E GF G P + G P+ PP P PA
Sbjct: 1140 --------KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--- 1188
Query: 1323 QPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSS 1382
P P PP G LG E E G SP ++ P
Sbjct: 1189 ---GPNGADGPQGPPGGVGNLGPPGEKGEPGESG----SP----------GIQGEPGVKG 1231
Query: 1383 DEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLPS 1441
+ K Q +P GPK + DGP P PG P PG
Sbjct: 1232 PRGERGEKGESGQPG---------EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGG 1282
Query: 1442 ANSNGTPEPPLLEEKPPPTP-PPAPTPQPQPPPP----PPPPQP----------ALPSPP 1486
+ E+ P P P PT + PP P P P A P
Sbjct: 1283 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1342
Query: 1487 PLVAPTPSSP--PPPPLPPPPPPAMPSPP----PPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
+ AP + P P P P P + P P A A PP P P P L
Sbjct: 1343 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP-GPVGP----PGL 1397
Query: 1541 PDTRPLHLAKKQE----TAAVCGETDEEAGESGGEGI 1573
P R AK ++ + G E+ GE G G+
Sbjct: 1398 PGLRGDAGAKGEKGHPGLIGLIGPPGEQ-GEKGDRGL 1433
Score = 48.1 bits (113), Expect = 9e-05
Identities = 110/450 (24%), Positives = 134/450 (29%), Gaps = 69/450 (15%)
Query: 1408 PPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLP-SANSNGTPEPPLLEEKPPPTPPPAP 1465
P + GP+ + GP PGPP GLP +A GT P PP P
Sbjct: 924 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP-----GPPGAPGKD 978
Query: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLA 1524
P P P P L PS PP P P A S P PP
Sbjct: 979 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 1038
Query: 1525 APPE---EPAAPSPEDPELPDTR-----PLHLAKKQETAAVCGETDEEAGESGGEGIFRE 1576
PP E P + P P R P+ L V GE D + GE G G +
Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-DGDKGEVGDPG---Q 1094
Query: 1577 RDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFG 1636
+ + E P P PI V + DG+ + G G
Sbjct: 1095 KGTKGNKGEHGPP--------GPPGPIGPVGQPGAAG-----ADGEPGARGPQGHFGAKG 1141
Query: 1637 DAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKA 1696
D R ++ PP P+ G G + P
Sbjct: 1142 DEGTR------------------------GFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1177
Query: 1697 PAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRG 1756
P PP P P P+ P P EK + E +G R RG
Sbjct: 1178 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1237
Query: 1757 ERATSGRQTRPERSLATGQPATSRLPKARPTKV--KAEPPPKKRKKWLKEAGGNATAGGG 1814
E+ SG+ P G P PK P V +P P GG G
Sbjct: 1238 EKGESGQPGEPGPPGPKG-PTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGA 1289
Query: 1815 PPGSSSDSE-SSPGAPS-EDERAVPGRLLK 1842
D E PG+P E PG L K
Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1319
Score = 46.2 bits (108), Expect = 3e-04
Identities = 61/237 (25%), Positives = 78/237 (32%), Gaps = 32/237 (13%)
Query: 1411 AGPKDTSTPDG-------------PPLAPAAAVPGPPPLPGLPSANSNGTPE-----PPL 1452
AGP PDG P A PGP PGLP + + P L
Sbjct: 1356 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1415
Query: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPPAMPS 1511
+ PP + P P P Q P P P PP P P P A +
Sbjct: 1416 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA 1475
Query: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE-----TDEEAG 1566
P P + PP P P LP P + + + + E T G
Sbjct: 1476 TGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPG 1535
Query: 1567 ESGG-EGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
GG E IF D E+I ++ TG + P Q L+ PE+ DG+
Sbjct: 1536 SPGGLEEIFGSLDSL---REEIEQMR--RPTGTQDSPARTCQD--LKLCHPELPDGE 1585
Score = 37.4 bits (85), Expect = 0.15
Identities = 47/171 (27%), Positives = 61/171 (35%), Gaps = 14/171 (8%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P + G +P G P PP P+ E P E P PP P
Sbjct: 893 PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPGP 950
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
L P KE K G G+ +G + P G P T+ P + +
Sbjct: 951 PGEQGL-PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE---RGLPGTAGGPGLKGNEG 1006
Query: 1790 KAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSDSESSPGAPSEDERAVPG 1838
+ PP + A G +GG GPPG + PGA E+ VPG
Sbjct: 1007 PSGPPGPAGSPGERGAAG---SGGPIGPPGRPG-PQGPPGAAG--EKGVPG 1051
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 110 bits (275), Expect = 1e-23
Identities = 253/954 (26%), Positives = 303/954 (31%), Gaps = 205/954 (21%)
Query: 212 GVLGPAGL----GPAQTP-----------PYRPGPPDPPPPPRHLPTQFNLLASSSAAAA 256
G++GP G+ GP P P G P PP LP +F
Sbjct: 301 GLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVV 360
Query: 257 AAEQSSPQ--LYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
AA+++ Q L A GPP P + + RP P
Sbjct: 361 AAQEAQAQAILQQARLALRGPPGP----------MGYTGRPGPLGQP------------- 397
Query: 315 SCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATA--GASGRATGPEAAGGGG 372
GS G +L P G P G P KAG G GA G P G G
Sbjct: 398 ---GSPGLKGESGDLG--PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 452
Query: 373 AGG-----------GGGGYRPIIQSPGYKTGKGGYG----------AAAGGATRPP-PPR 410
G G G + + PG +G G + G P PP
Sbjct: 453 FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 512
Query: 411 STATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQ-AYG-QGFGGGQAQD 468
P + + GP + G G GQ +PG QGL GPQ A G G G Q +
Sbjct: 513 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT-QGLPGPQGAIGPHGEKGPQGKP 571
Query: 469 LSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTAS 528
S GPP P PPG T + P QG L YPGP +G+
Sbjct: 572 GLPGMPGSDGPPGHPGKEGPPG--TKGNQGPSGPQGPL------GYPGP----RGVKGVD 619
Query: 529 PSLSYSTGHS--------PALSGHGGGWG-------PSSLGGGGEASPSHIIRPLQSPPA 573
+ GH P G G G P S G G P P P
Sbjct: 620 -GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG- 677
Query: 574 TGRPPGV----------GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSE 623
PPG+ G PG PG+ S F PGA S GA G GK G
Sbjct: 678 ---PPGLMGEKGKLGVPGLPGYPGR--QGPKGSLGFPGFPGA-SGEKGARGLSGKS-GPR 730
Query: 624 LLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDG--AADASKGLGGSGGAG 681
GP GP +R + TSG DG G G +G G G
Sbjct: 731 GERGPTGPRGQRGP------RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 784
Query: 682 GPPGTPYE--LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETP 739
GPPG P + L QR + +T G G E ERG P
Sbjct: 785 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ----GAAGETGPMGERGHPGP 840
Query: 740 EGLATSVVHYGAGAKELGAFLQKSPPPPP----PTAQSTQPTPHGLLLEAGGPDLPLVLP 795
G G KE G PP P P P GL AGGP L
Sbjct: 841 PGPPGEQGLPGTAGKE-GTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 899
Query: 796 PPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR 855
P P P P+ S + G A G P PP P P P
Sbjct: 900 PSGP----------PGPAGSPGERG------AAGSGGPIGPPGRPGPQGP---------- 933
Query: 856 SHGLEPAAPSPRLRPEES--LDPPG--AMQELLGALEPLPPA-----PGDTG-VGPPNSE 905
P A + P E + P G +Q +G P P GD G VG P +
Sbjct: 934 -----PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988
Query: 906 G-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGG-----GAA 959
G K G + P P G P P + + + + F +E G G
Sbjct: 989 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048
Query: 960 DDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPE 1017
G GP ++G+ GP PPGPP P GP P A GP+ P G+ PP
Sbjct: 1049 GLQGLPGPSGEKGET-GDVGPMGPPGPPG--PRGPAGPNGAD--GPQGPPGGVGNLGPPG 1103
Query: 1018 LPSTVNAEPLGLIQSGPHQAAP------------PPPPPPPPPPAPASE--PKG 1057
IQ P P P P PP P P + PKG
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1157
Score = 102 bits (254), Expect = 4e-21
Identities = 193/742 (26%), Positives = 235/742 (31%), Gaps = 125/742 (16%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G G GL Q P PGP PP PP F G
Sbjct: 764 GPPGERGLPGPQGPNGFPGPKGPPGPP-------------GKDGLPGHPGQRGEVGFQGK 810
Query: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLAC 331
GPP P + Q + P PP PP G+ G +
Sbjct: 811 T-GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ-----GLPGTAGKEGTK----- 859
Query: 332 SPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKT 391
G+P P G P K GP+G G G P AGG G G G P PG
Sbjct: 860 -----GDPGP-PGAPGKDGPAG-LRGFPGERGLPGTAGGPGLKGNEGPSGP----PGPAG 908
Query: 392 GKGGYGAAAGGATRPPP--PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQ-- 447
G GAA G PP P P G +G G G PG
Sbjct: 909 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 968
Query: 448 PQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP---PGLATCQSYSPDQLQG 504
P G+ G +G G Q +K GPP PP P PG A +
Sbjct: 969 PPGVAGEDG-DKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQ 1027
Query: 505 QLYGVQGEP-------YPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGG 557
+G +G+ PGP QGLP S G G GP +G G
Sbjct: 1028 GHFGAKGDEGTRGFNGPPGPIG-LQGLPGPSGE-----------KGETGDVGP--MGPPG 1073
Query: 558 EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKG 617
P P + G P GVG+ G PG+ + +P + G G KG
Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKG 1133
Query: 618 KGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGA-----ADASK 672
+ G GP GP +D + P P G G G+DGA D
Sbjct: 1134 E-SGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR--TSASLDEGATAALELGLGRLKEKKK 730
G GS G G G P L K P + A D GA A G+
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA----PGKTGPVGP 1248
Query: 731 GPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPP--PPTAQSTQPTPHGLLLEAGGP 788
G P+GL G + GA Q PP P PP + G E G P
Sbjct: 1249 AGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPVGPPGLPGLRGDA-GAKGEKGHP 1306
Query: 789 DL-PLVLPP-----------PPPQLLPSVLSHAPSPSPSA-----------SKVGVHLLE 825
L L+ PP P PQ P P S G +
Sbjct: 1307 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1366
Query: 826 PATRDGAP------QPPPPPPPPP----PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD 875
AT G P Q PP P PP P+P+Q+ R + RL E+
Sbjct: 1367 GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR-----SVDGSRLMQEDEAI 1421
Query: 876 P-------PGAMQELLGALEPL 890
P PG ++E+ G+L+ L
Sbjct: 1422 PTGGAPGSPGGLEEIFGSLDSL 1443
Score = 72.0 bits (175), Expect = 6e-12
Identities = 298/1247 (23%), Positives = 383/1247 (30%), Gaps = 228/1247 (18%)
Query: 422 GPAAAYATGKASGAGGAGGQAYSPGQPQ---GLLGPQAYGQGFGGGQAQDLSKAPSYSGG 478
G AAY + + GGQ P Q PQ Q Q+ ++
Sbjct: 213 GVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPR 272
Query: 479 PPQPPSGPPP---PGLATCQSYSPDQLQGQLY--GVQGEPYP-------GPAAHSQGLPT 526
+ G P PG+ P+ G + G+QG P P GP + GLP
Sbjct: 273 GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-GLPG 331
Query: 527 A--SPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP----LQSPPA----TGR 576
+ +P ++ P G GGG + EA I++ L+ PP TGR
Sbjct: 332 SDGAPGPPGTSLMLPFRFGSGGG-DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR 390
Query: 577 PPGVGSPGAPG-KYLSSVL------ASAPFLAPPGAGSY--AAGAGGYKG-KGD----GS 622
P +G PG+PG K S L PPG AGA G +G GD G
Sbjct: 391 PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGD 450
Query: 623 ELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADAS--KGLGGSGGA 680
G G P E+ + Q L P G DG +G G S +GL G G
Sbjct: 451 RGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGP 510
Query: 681 GGPPGTPYELAKEDPQ----RYHLQSVIRTSASLDEGATAALELGLGRL-KEKKKGPERG 735
G PG P + PQ Q T L G + +KGP+
Sbjct: 511 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGK 570
Query: 736 GETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLP 795
P G+ S G KE + + P P P P G+ G L
Sbjct: 571 PGLP-GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG 629
Query: 796 PPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATR-DGAPQPPP----PPPPPPPPMPLQL 850
P +VGV P +R + P+ P P P PP +
Sbjct: 630 EKGEDGFPGFKGDI-GVKGDRGEVGV----PGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684
Query: 851 EAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGV-GPPNSEGKDP 909
+ L GL P P R P+ SL PG P A G+ G G G P
Sbjct: 685 KGKLGVPGL-PGYPG-RQGPKGSLGFPG-----------FPGASGEKGARGLSGKSG--P 729
Query: 910 AGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPE 969
G P+G + PR + G + G GPP
Sbjct: 730 RGERGPTGPRGQRGPR----------------------GATGKSGAKGTSGGDGPHGPPG 767
Query: 970 DEG-----DPKAGAGP--PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTV 1022
+ G P GP PPGPP D P PG+ G + PP P V
Sbjct: 768 ERGLPGPQGPNGFPGPKGPPGPPGKDGL-PGHPGQRGEVGFQ------GKTGPPGPPGVV 820
Query: 1023 NAEPLGLI-QSGP--HQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFH 1079
P G ++GP + P PP PP P + K G
Sbjct: 821 G--PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD----------------- 861
Query: 1080 LLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL----NPRRLPDLVSSCRSRPALS 1135
PP K A F + L P P S R A
Sbjct: 862 ----PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 917
Query: 1136 PLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIR-PLEVPTTAGPASASTPT 1194
G I P PGP GP + GP P GR ++ P+ +P AGP +
Sbjct: 918 SGGPIG-PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVA-GE 975
Query: 1195 DGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSL 1254
DG K G +G K + P P+ P G + G+ +
Sbjct: 976 DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG-----PVGQPGAAGADGEPGARGPQGHF 1030
Query: 1255 DSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHP--PLYQAGLTPPLSPPKS 1312
+ K E GF G P + G P+ PP
Sbjct: 1031 GA----------------KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074
Query: 1313 VPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKR 1372
P PA P P PP G LG E E G SP
Sbjct: 1075 PGPRGPA------GPNGADGPQGPPGGVGNLGPPGEKGEPGESG----SP---------- 1114
Query: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA-AAVP 1431
++ P + K Q +P GPK + DGP P P
Sbjct: 1115 GIQGEPGVKGPRGERGEKGESGQPG---------EPGPPGPKGPTGDDGPKGNPGPVGFP 1165
Query: 1432 GPPPLPGLPSANSNGTPEPPLLEEKPPPTP-PPAPTPQPQPPPP----PPPPQP------ 1480
G P PG + E+ P P P PT + PP P P P
Sbjct: 1166 GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQ 1225
Query: 1481 ----ALPSPPPLVAPTPSSP--PPPPLPPPPPPAMPSPP----PPPPPAAAPLAAPPEEP 1530
A P + AP + P P P P P + P P A A PP P
Sbjct: 1226 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP-GP 1284
Query: 1531 AAPSPEDPELPDTRPLHLAKKQE----TAAVCGETDEEAGESGGEGI 1573
P P LP R AK ++ + G E+ GE G G+
Sbjct: 1285 VGP----PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ-GEKGDRGL 1326
Score = 48.1 bits (113), Expect = 9e-05
Identities = 110/450 (24%), Positives = 134/450 (29%), Gaps = 69/450 (15%)
Query: 1408 PPLAGPKDTSTPDGPPLAPA-AAVPGPPPLPGLP-SANSNGTPEPPLLEEKPPPTPPPAP 1465
P + GP+ + GP PGPP GLP +A GT P PP P
Sbjct: 817 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP-----GPPGAPGKD 871
Query: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLA 1524
P P P P L PS PP P P A S P PP
Sbjct: 872 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 931
Query: 1525 APPE---EPAAPSPEDPELPDTR-----PLHLAKKQETAAVCGETDEEAGESGGEGIFRE 1576
PP E P + P P R P+ L V GE D + GE G G +
Sbjct: 932 GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGE-DGDKGEVGDPG---Q 987
Query: 1577 RDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFG 1636
+ + E P P PI V + DG+ + G G
Sbjct: 988 KGTKGNKGEHGPP--------GPPGPIGPVGQPGAAG-----ADGEPGARGPQGHFGAKG 1034
Query: 1637 DAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKA 1696
D R ++ PP P+ G G + P
Sbjct: 1035 DEGTR------------------------GFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1070
Query: 1697 PAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRG 1756
P PP P P P+ P P EK + E +G R RG
Sbjct: 1071 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130
Query: 1757 ERATSGRQTRPERSLATGQPATSRLPKARPTKV--KAEPPPKKRKKWLKEAGGNATAGGG 1814
E+ SG+ P G P PK P V +P P GG G
Sbjct: 1131 EKGESGQPGEPGPPGPKG-PTGDDGPKGNPGPVGFPGDPGPPGE-------GGPRGQDGA 1182
Query: 1815 PPGSSSDSE-SSPGAPS-EDERAVPGRLLK 1842
D E PG+P E PG L K
Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGK 1212
Score = 46.2 bits (108), Expect = 3e-04
Identities = 61/237 (25%), Positives = 78/237 (32%), Gaps = 32/237 (13%)
Query: 1411 AGPKDTSTPDG-------------PPLAPAAAVPGPPPLPGLPSANSNGTPE-----PPL 1452
AGP PDG P A PGP PGLP + + P L
Sbjct: 1249 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1308
Query: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT-PSSPPPPPLPPPPPPAMPS 1511
+ PP + P P P Q P P P PP P P P A +
Sbjct: 1309 IGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGA 1368
Query: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE-----TDEEAG 1566
P P + PP P P LP P + + + + E T G
Sbjct: 1369 TGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPG 1428
Query: 1567 ESGG-EGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
GG E IF D E+I ++ TG + P Q L+ PE+ DG+
Sbjct: 1429 SPGGLEEIFGSLDSL---REEIEQMR--RPTGTQDSPARTCQD--LKLCHPELPDGE 1478
Score = 37.4 bits (85), Expect = 0.15
Identities = 47/171 (27%), Positives = 61/171 (35%), Gaps = 14/171 (8%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P + G +P G P PP P+ E P E P PP P
Sbjct: 786 PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP--MGERGHPGPPGP 843
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
L P KE K G G+ +G + P G P T+ P + +
Sbjct: 844 PGEQGL-PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE---RGLPGTAGGPGLKGNEG 899
Query: 1790 KAEPPPKKRKKWLKEAGGNATAGG--GPPGSSSDSESSPGAPSEDERAVPG 1838
+ PP + A G +GG GPPG + PGA E+ VPG
Sbjct: 900 PSGPPGPAGSPGERGAAG---SGGPIGPPGRPG-PQGPPGAAG--EKGVPG 944
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 109 bits (272), Expect = 3e-23
Identities = 99/309 (32%), Positives = 129/309 (41%), Gaps = 76/309 (24%)
Query: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRH-PPLYQAGLTPPLSPPKS--VPPS 1316
+++I + +++E + ++ +G +A L+ K+ L A +T P S P VPP+
Sbjct: 518 KQQIATEKQDLEAEVSQL-TGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 576
Query: 1317 VPARG----LQPQPPA-----TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
P G + P PPA TP P PPP L G G+ SP
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG----------GVCISSP----- 621
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
+LP +AIS PPL+G D + P PPL
Sbjct: 622 -------PSLPG-------------------GTAISP--PPPLSG--DATIPPPPPLPEG 651
Query: 1428 AAVPGPPPLPGLPSANSNGTPEPPLL--EEKPPPTPPPAPTPQPQPPPPPP-PPQPALPS 1484
+P P LPG P PP L + PP PPP P PPPPPP P + +P
Sbjct: 652 VGIPSPSSLPG-----GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPP 706
Query: 1485 PPPLVAPTPSSPPPPPLP-----PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE--- 1536
PPP + P PPPPP P PPPPP M PPPPP P A P P +P+
Sbjct: 707 PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP--AAPVLPFGLTPKKLY 764
Query: 1537 DPELPDTRP 1545
PE+ RP
Sbjct: 765 KPEVQLRRP 773
Score = 94.4 bits (233), Expect = 1e-18
Identities = 73/233 (31%), Positives = 96/233 (41%), Gaps = 69/233 (29%)
Query: 1364 KRLDEELKRNLETLP----SFSSDEEDSVAKNRDLQESISSAISA-------LDDPP--- 1409
K+++ + ++ L+ L + S+++ + +DL+ +S L+D
Sbjct: 494 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 553
Query: 1410 --LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
L+ T P P AP VP PPLPG +GT PP PP P + TP
Sbjct: 554 ASLSAAAITVPPSVPSRAP---VPPAPPLPG-----DSGTIIPP------PPAPGDSTTP 599
Query: 1468 QPQPPPPPPPPQ----------PALP-----SPPPLVAPTPSSPPPPPL----------- 1501
P PPPPPPPP P+LP SPPP ++ + PPPPPL
Sbjct: 600 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 659
Query: 1502 -------PPPPP-PAMPSPPPPPPPAAAPLAAPPEEPAAPS-----PEDPELP 1541
PPPPP P PPPPPP PP P P P P LP
Sbjct: 660 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712
Score = 77.0 bits (188), Expect = 2e-13
Identities = 62/209 (29%), Positives = 81/209 (38%), Gaps = 30/209 (14%)
Query: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLP--LVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
+PPPPPP P P G+ + + P LP + PPPP + A P P G
Sbjct: 598 TPPPPPPPPPPPPPLPGGVCI-SSPPSLPGGTAISPPPP-----LSGDATIPPPPPLPEG 651
Query: 821 VHLLEPATRDGAPQPPPPP--------PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872
V + P++ G PPPP PPPPPP+P S G+ P P P L E
Sbjct: 652 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-------GSAGIPP--PPPPLPGEA 702
Query: 873 SLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI 932
+ PP + P PP PG G+ PP P P P G P L
Sbjct: 703 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPP-----PPGMGMPPPPPFGFGVPAAPVLPFG 757
Query: 933 CFPDSLLQDEERSFFPTMEEMFGGGAADD 961
P L + E + P ++ + D
Sbjct: 758 LTPKKLYKPEVQLRRPNWSKLVAEDLSQD 786
Score = 65.5 bits (158), Expect = 5e-10
Identities = 65/244 (26%), Positives = 86/244 (35%), Gaps = 59/244 (24%)
Query: 788 PDLPLVLPPPPPQLLP----SVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843
P +P P PP LP +++ P+P S + P PPPPPPPPP
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP-------------PPPPPPPPPPPP 611
Query: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903
P + + + G +P P L + ++ PP + E +G P PG T + PP
Sbjct: 612 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSP-SSLPGGTAIPPPP 670
Query: 904 SEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
P A P P +P P G
Sbjct: 671 PL---PGSARIPPPPPPLPGSAGIPPPPPPLP---------------------------G 700
Query: 964 KAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
+AG P G G PP PP P GP G P PG+G+ P PP V
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPF--PGGP-------GIPPPPPGMGMPP--PPPFGFGVP 749
Query: 1024 AEPL 1027
A P+
Sbjct: 750 AAPV 753
Score = 55.8 bits (133), Expect = 4e-07
Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 39/190 (20%)
Query: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
PS+AP VP + +G + P G + TPP PP PPPPP LP + + S
Sbjct: 568 PSRAP-VPPAPPLPGDSGTIIPPPPAPGDSTTPP---PPPPPPPPPPPLPGGVCISSPPS 623
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPE-------RALPRQDTVIKHYQRPASAQPPPPPP 305
A P L + P PP PE +LP + P SA+ PPPPP
Sbjct: 624 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP 683
Query: 306 PAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG---PSGATAGASGRA 362
P P G P P P +AG P G G
Sbjct: 684 PL-------------------------PGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 718
Query: 363 TGPEAAGGGG 372
P GG G
Sbjct: 719 PPPPFPGGPG 728
Score = 52.0 bits (123), Expect = 6e-06
Identities = 69/232 (29%), Positives = 80/232 (34%), Gaps = 57/232 (24%)
Query: 889 PLPPAPGDTG--VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTS---ICFPDSLLQDEE 943
P PP PGD+G + PP + G +P P P PL I P SL
Sbjct: 575 PAPPLPGDSGTIIPPPPAPGDST-----TPPPPPPPPPPPPPLPGGVCISSPPSL----- 624
Query: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCP-----GRA 998
GG A + PP GD A PP PP + G P G A
Sbjct: 625 -----------PGGTAI----SPPPPLSGD----ATIPPPPPLPEGVGIPSPSSLPGGTA 665
Query: 999 SGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP------PPPPPPAPA 1052
P PG P PP LP + P G PPPPP PPPPP P
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 725
Query: 1053 S----EPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYE 1100
P G+ P P + +L P TPKKLY E +
Sbjct: 726 GPGIPPPPPGMGMP----PPPPFGFGVPAAPVL----PFGLTPKKLYKPEVQ 769
Score = 45.1 bits (105), Expect = 7e-04
Identities = 58/200 (29%), Positives = 64/200 (32%), Gaps = 51/200 (25%)
Query: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQG----LLGP 454
A G +T PPPP P GG +S GG A SP P + P
Sbjct: 592 APGDSTTPPPPPPPPPPPPPLPGGVCI------SSPPSLPGGTAISPPPPLSGDATIPPP 645
Query: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514
+G G + S GG PP PP PG A P
Sbjct: 646 PPLPEGVG------IPSPSSLPGGTAIPPP-PPLPGSARI-----------------PPP 681
Query: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWG----PSSLGGGGEASPSHIIRPLQS 570
P P S G+P P L G P GG G P GG G P
Sbjct: 682 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP--------- 732
Query: 571 PPATGRPP----GVGSPGAP 586
PP G PP G G P AP
Sbjct: 733 PPGMGMPPPPPFGFGVPAAP 752
Score = 43.9 bits (102), Expect = 0.002
Identities = 61/221 (27%), Positives = 68/221 (30%), Gaps = 59/221 (26%)
Query: 981 PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
PP P+ P P P PG PP P P PP
Sbjct: 564 PPSVPSRAPVPP---------APPLPGDSGTIIPPPPAPGDSTTPP------------PP 602
Query: 1041 PPPPPPPPP--------APASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPK 1092
PPPPPPPPP +P S P G SP P L ++ PP P
Sbjct: 603 PPPPPPPPPLPGGVCISSPPSLPGGTAISP------PPPLSGDATI------PPPPPLP- 649
Query: 1093 KLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGP 1152
E + +P + P P L S R P PL PP P P P
Sbjct: 650 -------EGVGIPSPSSLPGGTAIPPP--PPLPGSARIPPPPPPLPGSAGIPP-PPPPLP 699
Query: 1153 RRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTP 1193
G P PP G P I P P GP P
Sbjct: 700 GEAGMPPP------PPPLPGGPGIPP-PPPFPGGPGIPPPP 733
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 25/58 (43%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP+P P + G S+ PPP P PPP P P PP TA+ PP
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 634
Score = 40.8 bits (94), Expect = 0.014
Identities = 50/175 (28%), Positives = 60/175 (34%), Gaps = 39/175 (22%)
Query: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA 196
PG ST P P P P+P + + PP S P +SP L +
Sbjct: 593 PGDSTTPPP--------PPPPPPPPPPLPGGVCISSPP-SLPGGTAISPPPPLSGDATIP 643
Query: 197 PTVPSSLGFERLAGGGVLGPAGL-GPAQTPPYRPGP-----PDPPPPPRHLPTQFNLLAS 250
P P G G+ P+ L G PP P P P PPPP LP
Sbjct: 644 PPPPLPEGV------GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP---LP-------- 686
Query: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305
+A P L +G P PPP LP + P PPPPP
Sbjct: 687 ---GSAGIPPPPPPLPGEAGMPPPPPP----LPGGPGIPPPPPFPGGPGIPPPPP 734
Score = 40.4 bits (93), Expect = 0.018
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPA------PPPKPETPEKTTSEKPPEQTP-ETA 1722
PP P+ +P S G +A PP P PPP P P PP P E
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Query: 1723 MPEPPAP 1729
MP PP P
Sbjct: 704 MPPPPPP 710
Score = 37.0 bits (84), Expect = 0.20
Identities = 47/156 (30%), Positives = 50/156 (32%), Gaps = 33/156 (21%)
Query: 472 APSYSGGPPQPPSGPPPPGL---ATCQSYSPDQLQG--------QLYGVQGEPYPGPAAH 520
AP S PP PP PPPP C S SP L G L G P P P
Sbjct: 592 APGDSTTPPPPPPPPPPPPPLPGGVCIS-SPPSLPGGTAISPPPPLSGDATIPPPPPLPE 650
Query: 521 SQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEAS------PSHIIRPLQSPPAT 574
G+P+ S SL T P P L G P P PP
Sbjct: 651 GVGIPSPS-SLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 699
Query: 575 GR----PPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G PP PG PG P + PP G
Sbjct: 700 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG 735
Score = 36.6 bits (83), Expect = 0.26
Identities = 30/114 (26%), Positives = 40/114 (35%), Gaps = 22/114 (19%)
Query: 125 PGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS 184
P P L +P S+ P +A+ P P+P S + PP P + +
Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIP 692
Query: 185 PHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
P + P P L P G G PP+ GP PPPPP
Sbjct: 693 PPPPPLPGEAGMPPPPPPL------------PGGPGIPPPPPFPGGPGIPPPPP 734
Score = 35.4 bits (80), Expect = 0.57
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 16/100 (16%)
Query: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP-----PPKPETPEKTTSEKPPEQ 1717
AR P PP+P P G + PPP P P PP P P PP
Sbjct: 676 ARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP-- 733
Query: 1718 TPETAMPEPP--------APEKPSLLRPVEKEKEKEKVTR 1749
P MP PP AP P L P + K + ++ R
Sbjct: 734 -PGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRR 772
Score = 33.1 bits (74), Expect = 2.8
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 1684 VSAGGSSAPPP---KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732
+SA + PP +AP PP P + T PP ++ P PP P P
Sbjct: 556 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP 607
Score = 32.0 bits (71), Expect = 6.3
Identities = 24/87 (27%), Positives = 29/87 (33%), Gaps = 18/87 (20%)
Query: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP---------------APPPKPET 1705
VC P P +P + P+S + PPP P A PP P
Sbjct: 616 VCISSP---PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 672
Query: 1706 PEKTTSEKPPEQTPETAMPEPPAPEKP 1732
P PP P +A PP P P
Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLP 699
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 109 bits (272), Expect = 3e-23
Identities = 99/309 (32%), Positives = 129/309 (41%), Gaps = 76/309 (24%)
Query: 1260 REKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRH-PPLYQAGLTPPLSPPKS--VPPS 1316
+++I + +++E + ++ +G +A L+ K+ L A +T P S P VPP+
Sbjct: 527 KQQIATEKQDLEAEVSQL-TGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585
Query: 1317 VPARG----LQPQPPA-----TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLD 1367
P G + P PPA TP P PPP L G G+ SP
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPG----------GVCISSP----- 630
Query: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPA 1427
+LP +AIS PPL+G D + P PPL
Sbjct: 631 -------PSLPG-------------------GTAISP--PPPLSG--DATIPPPPPLPEG 660
Query: 1428 AAVPGPPPLPGLPSANSNGTPEPPLL--EEKPPPTPPPAPTPQPQPPPPPP-PPQPALPS 1484
+P P LPG P PP L + PP PPP P PPPPPP P + +P
Sbjct: 661 VGIPSPSSLPG-----GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPP 715
Query: 1485 PPPLVAPTPSSPPPPPLP-----PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPE--- 1536
PPP + P PPPPP P PPPPP M PPPPP P A P P +P+
Sbjct: 716 PPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVP--AAPVLPFGLTPKKLY 773
Query: 1537 DPELPDTRP 1545
PE+ RP
Sbjct: 774 KPEVQLRRP 782
Score = 94.4 bits (233), Expect = 1e-18
Identities = 73/233 (31%), Positives = 96/233 (41%), Gaps = 69/233 (29%)
Query: 1364 KRLDEELKRNLETLP----SFSSDEEDSVAKNRDLQESISSAISA-------LDDPP--- 1409
K+++ + ++ L+ L + S+++ + +DL+ +S L+D
Sbjct: 503 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 562
Query: 1410 --LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
L+ T P P AP VP PPLPG +GT PP PP P + TP
Sbjct: 563 ASLSAAAITVPPSVPSRAP---VPPAPPLPG-----DSGTIIPP------PPAPGDSTTP 608
Query: 1468 QPQPPPPPPPPQ----------PALP-----SPPPLVAPTPSSPPPPPL----------- 1501
P PPPPPPPP P+LP SPPP ++ + PPPPPL
Sbjct: 609 PPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSS 668
Query: 1502 -------PPPPP-PAMPSPPPPPPPAAAPLAAPPEEPAAPS-----PEDPELP 1541
PPPPP P PPPPPP PP P P P P LP
Sbjct: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721
Score = 77.0 bits (188), Expect = 2e-13
Identities = 62/209 (29%), Positives = 81/209 (38%), Gaps = 30/209 (14%)
Query: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLP--LVLPPPPPQLLPSVLSHAPSPSPSASKVG 820
+PPPPPP P P G+ + + P LP + PPPP + A P P G
Sbjct: 607 TPPPPPPPPPPPPPLPGGVCI-SSPPSLPGGTAISPPPP-----LSGDATIPPPPPLPEG 660
Query: 821 VHLLEPATRDGAPQPPPPP--------PPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872
V + P++ G PPPP PPPPPP+P S G+ P P P L E
Sbjct: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-------GSAGIPP--PPPPLPGEA 711
Query: 873 SLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI 932
+ PP + P PP PG G+ PP P P P G P L
Sbjct: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPP-----PPGMGMPPPPPFGFGVPAAPVLPFG 766
Query: 933 CFPDSLLQDEERSFFPTMEEMFGGGAADD 961
P L + E + P ++ + D
Sbjct: 767 LTPKKLYKPEVQLRRPNWSKLVAEDLSQD 795
Score = 65.5 bits (158), Expect = 5e-10
Identities = 65/244 (26%), Positives = 86/244 (35%), Gaps = 59/244 (24%)
Query: 788 PDLPLVLPPPPPQLLP----SVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843
P +P P PP LP +++ P+P S + P PPPPPPPPP
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTP-------------PPPPPPPPPPPP 620
Query: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPN 903
P + + + G +P P L + ++ PP + E +G P PG T + PP
Sbjct: 621 LPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSP-SSLPGGTAIPPPP 679
Query: 904 SEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYG 963
P A P P +P P G
Sbjct: 680 PL---PGSARIPPPPPPLPGSAGIPPPPPPLP---------------------------G 709
Query: 964 KAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVN 1023
+AG P G G PP PP P GP G P PG+G+ P PP V
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPF--PGGP-------GIPPPPPGMGMPP--PPPFGFGVP 758
Query: 1024 AEPL 1027
A P+
Sbjct: 759 AAPV 762
Score = 55.8 bits (133), Expect = 4e-07
Identities = 55/190 (28%), Positives = 67/190 (35%), Gaps = 39/190 (20%)
Query: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSS 252
PS+AP VP + +G + P G + TPP PP PPPPP LP + + S
Sbjct: 577 PSRAP-VPPAPPLPGDSGTIIPPPPAPGDSTTPP---PPPPPPPPPPPLPGGVCISSPPS 632
Query: 253 AAAAAAEQSSPQLYNFSGAAPGPPPPE-------RALPRQDTVIKHYQRPASAQPPPPPP 305
A P L + P PP PE +LP + P SA+ PPPPP
Sbjct: 633 LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP 692
Query: 306 PAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG---PSGATAGASGRA 362
P P G P P P +AG P G G
Sbjct: 693 PL-------------------------PGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIP 727
Query: 363 TGPEAAGGGG 372
P GG G
Sbjct: 728 PPPPFPGGPG 737
Score = 52.0 bits (123), Expect = 6e-06
Identities = 69/232 (29%), Positives = 80/232 (34%), Gaps = 57/232 (24%)
Query: 889 PLPPAPGDTG--VGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTS---ICFPDSLLQDEE 943
P PP PGD+G + PP + G +P P P PL I P SL
Sbjct: 584 PAPPLPGDSGTIIPPPPAPGDST-----TPPPPPPPPPPPPPLPGGVCISSPPSL----- 633
Query: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCP-----GRA 998
GG A + PP GD A PP PP + G P G A
Sbjct: 634 -----------PGGTAI----SPPPPLSGD----ATIPPPPPLPEGVGIPSPSSLPGGTA 674
Query: 999 SGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPP------PPPPPPAPA 1052
P PG P PP LP + P G PPPPP PPPPP P
Sbjct: 675 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 734
Query: 1053 S----EPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYE 1100
P G+ P P + +L P TPKKLY E +
Sbjct: 735 GPGIPPPPPGMGMP----PPPPFGFGVPAAPVL----PFGLTPKKLYKPEVQ 778
Score = 45.1 bits (105), Expect = 7e-04
Identities = 58/200 (29%), Positives = 64/200 (32%), Gaps = 51/200 (25%)
Query: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQG----LLGP 454
A G +T PPPP P GG +S GG A SP P + P
Sbjct: 601 APGDSTTPPPPPPPPPPPPPLPGGVCI------SSPPSLPGGTAISPPPPLSGDATIPPP 654
Query: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514
+G G + S GG PP PP PG A P
Sbjct: 655 PPLPEGVG------IPSPSSLPGGTAIPPP-PPLPGSARI-----------------PPP 690
Query: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWG----PSSLGGGGEASPSHIIRPLQS 570
P P S G+P P L G P GG G P GG G P
Sbjct: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPP--------- 741
Query: 571 PPATGRPP----GVGSPGAP 586
PP G PP G G P AP
Sbjct: 742 PPGMGMPPPPPFGFGVPAAP 761
Score = 43.9 bits (102), Expect = 0.002
Identities = 61/221 (27%), Positives = 68/221 (30%), Gaps = 59/221 (26%)
Query: 981 PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040
PP P+ P P P PG PP P P PP
Sbjct: 573 PPSVPSRAPVPP---------APPLPGDSGTIIPPPPAPGDSTTPP------------PP 611
Query: 1041 PPPPPPPPP--------APASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPK 1092
PPPPPPPPP +P S P G SP P L ++ PP P
Sbjct: 612 PPPPPPPPPLPGGVCISSPPSLPGGTAISP------PPPLSGDATI------PPPPPLP- 658
Query: 1093 KLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGP 1152
E + +P + P P L S R P PL PP P P P
Sbjct: 659 -------EGVGIPSPSSLPGGTAIPPP--PPLPGSARIPPPPPPLPGSAGIPP-PPPPLP 708
Query: 1153 RRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTP 1193
G P PP G P I P P GP P
Sbjct: 709 GEAGMPPP------PPPLPGGPGIPP-PPPFPGGPGIPPPP 742
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 25/58 (43%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP 1727
PP+P P + G S+ PPP P PPP P P PP TA+ PP
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 643
Score = 40.8 bits (94), Expect = 0.014
Identities = 50/175 (28%), Positives = 60/175 (34%), Gaps = 39/175 (22%)
Query: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA 196
PG ST P P P P+P + + PP S P +SP L +
Sbjct: 602 PGDSTTPPP--------PPPPPPPPPPLPGGVCISSPP-SLPGGTAISPPPPLSGDATIP 652
Query: 197 PTVPSSLGFERLAGGGVLGPAGL-GPAQTPPYRPGP-----PDPPPPPRHLPTQFNLLAS 250
P P G G+ P+ L G PP P P P PPPP LP
Sbjct: 653 PPPPLPEGV------GIPSPSSLPGGTAIPPPPPLPGSARIPPPPPP---LP-------- 695
Query: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPP 305
+A P L +G P PPP LP + P PPPPP
Sbjct: 696 ---GSAGIPPPPPPLPGEAGMPPPPPP----LPGGPGIPPPPPFPGGPGIPPPPP 743
Score = 40.4 bits (93), Expect = 0.018
Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPA------PPPKPETPEKTTSEKPPEQTP-ETA 1722
PP P+ +P S G +A PP P PPP P P PP P E
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Query: 1723 MPEPPAP 1729
MP PP P
Sbjct: 713 MPPPPPP 719
Score = 37.0 bits (84), Expect = 0.20
Identities = 47/156 (30%), Positives = 50/156 (32%), Gaps = 33/156 (21%)
Query: 472 APSYSGGPPQPPSGPPPPGL---ATCQSYSPDQLQG--------QLYGVQGEPYPGPAAH 520
AP S PP PP PPPP C S SP L G L G P P P
Sbjct: 601 APGDSTTPPPPPPPPPPPPPLPGGVCIS-SPPSLPGGTAISPPPPLSGDATIPPPPPLPE 659
Query: 521 SQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEAS------PSHIIRPLQSPPAT 574
G+P+ S SL T P P L G P P PP
Sbjct: 660 GVGIPSPS-SLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIPPPPPPLP 708
Query: 575 GR----PPGVGSPGAPGKYLSSVLASAPFLAPPGAG 606
G PP PG PG P + PP G
Sbjct: 709 GEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG 744
Score = 36.6 bits (83), Expect = 0.26
Identities = 30/114 (26%), Positives = 40/114 (35%), Gaps = 22/114 (19%)
Query: 125 PGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS 184
P P L +P S+ P +A+ P P+P S + PP P + +
Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPP----------PPPLPGSARIPPPPPPLPGSAGIP 701
Query: 185 PHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
P + P P L P G G PP+ GP PPPPP
Sbjct: 702 PPPPPLPGEAGMPPPPPPL------------PGGPGIPPPPPFPGGPGIPPPPP 743
Score = 35.4 bits (80), Expect = 0.57
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 16/100 (16%)
Query: 1663 ARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAP-----PPKPETPEKTTSEKPPEQ 1717
AR P PP+P P G + PPP P P PP P P PP
Sbjct: 685 ARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPP-- 742
Query: 1718 TPETAMPEPP--------APEKPSLLRPVEKEKEKEKVTR 1749
P MP PP AP P L P + K + ++ R
Sbjct: 743 -PGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRR 781
Score = 33.1 bits (74), Expect = 2.8
Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 1684 VSAGGSSAPPP---KAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732
+SA + PP +AP PP P + T PP ++ P PP P P
Sbjct: 565 LSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP 616
Score = 32.0 bits (71), Expect = 6.3
Identities = 24/87 (27%), Positives = 29/87 (33%), Gaps = 18/87 (20%)
Query: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAP---------------APPPKPET 1705
VC P P +P + P+S + PPP P A PP P
Sbjct: 625 VCISSP---PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681
Query: 1706 PEKTTSEKPPEQTPETAMPEPPAPEKP 1732
P PP P +A PP P P
Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLP 708
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 108 bits (270), Expect = 5e-23
Identities = 210/794 (26%), Positives = 254/794 (31%), Gaps = 173/794 (21%)
Query: 163 PVPSSLSLQDPPFSPPAN-GLLSPHDVLHLKPSQAPTVP-------------SSLGFERL 208
P P S D P PP G P + + P P GF+
Sbjct: 912 PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 971
Query: 209 AG----GGVLGPAGLGPAQTPPYRPGPPDPPPPP--RHLPTQFNLLASSSAAAAAAEQSS 262
G GGV+GP G P G P PP PP + LP AA +
Sbjct: 972 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP---------GAAGKEGAKGD 1022
Query: 263 PQLYNFSGAAPGPP-----PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG 317
P SG GP P ER LP P PP P + S G
Sbjct: 1023 PGPQGISG-KDGPAGLRGFPGERGLPGAQGA---PGLKGGEGPQGPPGPVGSPGERGSAG 1078
Query: 318 GSYPSMGHRANLACSPLGGGEPSPGA--GEPSKAGPSGATA--GASGRATGPEAAGGGGA 373
+ P L P G P P G P + GP G G G P AG G+
Sbjct: 1079 TAGP-----IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133
Query: 374 GGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS 433
G G + I PG K KG G PP P P +G P A G+
Sbjct: 1134 PGEDGD-KGEIGEPGQKGSKGD-----KGENGPPGPPGLQGP----VGAPGIAGGDGEPG 1183
Query: 434 GAGGAG--------GQAYSPGQP-----QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480
G G G PG P QGL GP G + ++ P GPP
Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP-------GEKGENGDVGPMGPPGPP 1236
Query: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
P GP P A P + G + GV + PG A +P
Sbjct: 1237 -GPRGPQGPNGADGPQGPPGSV-GSVGGVGEKGEPGEAG------------------NPG 1276
Query: 541 LSGHGGGWGP-SSLGGGGEASPSHIIRP--LQSPPA----TGRPPGVGSPGAPGKYLSSV 593
G G GP G GEA P P + PP G P VG PG PG
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG------ 1330
Query: 594 LASAPFLAPPGAGSYAA--GAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPS 651
PPG A G GG KG+ DG GP GP E P
Sbjct: 1331 --------PPGEPGPAGQDGVGGDKGE-DGDPGQPGPPGPSGE------------AGPPG 1369
Query: 652 PPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR--TSAS 709
PP G G G +G KG G GA GPPG + + P +R
Sbjct: 1370 PPGKRGPPGAAGAEG-RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428
Query: 710 LDEGATAAL-------ELGLGRLKEKKKGPERGGETPE-GLATSVVHYGAGAKELGAFLQ 761
++G A +G L K P GE GL + G ++ L
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1488
Query: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGV 821
+ P P P G L G P LP P P+ + S P+ K
Sbjct: 1489 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP---GPQGPK------GNKGSTGPAGQK--- 1536
Query: 822 HLLEPATRDGAPQPPPPPPPPP---PPMPLQLEAHLRSH--GLEPAAPSPRLRPEESLDP 876
G P PP P PP P+P+ R H G++ A + LD
Sbjct: 1537 ------GDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA------DDNILDY 1584
Query: 877 PGAMQELLGALEPL 890
M+E+ G+L L
Sbjct: 1585 SDGMEEIFGSLNSL 1598
Score = 105 bits (263), Expect = 3e-22
Identities = 309/1241 (24%), Positives = 396/1241 (31%), Gaps = 259/1241 (20%)
Query: 174 PFSPPANGLLSPHDVLHLKP-------SQAPTVPSS-------LGFERLAGGGVLGPAGL 219
P P A+GL P + + P S+ PT+ + L R+A G GP GL
Sbjct: 489 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 548
Query: 220 ----GPAQTPPYR--------PGPPDP-----PPPPRHLPTQFNLLASSSAAAAAAEQSS 262
GP P PGP P PP P P + + E +
Sbjct: 549 TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608
Query: 263 PQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS 322
F G PG P K ++ Q PP PP ++ G
Sbjct: 609 KGDRGFDGL-PGLPGD-----------KGHRGERGPQGPPGPPGDDGMRGE---DGEIGP 653
Query: 323 MGHRANLACSPLGGGEPSPGA-GEPSKAGPSG-----ATAGASGRATGPEAAGGGGAGGG 376
G L G +PGA G+P AG G G G P G G G
Sbjct: 654 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 713
Query: 377 GGGYRPIIQSPGYKTGKGGYGAAA-GGATRPP--PPRSTATPKCQSLGGPAAAYATGK-- 431
G PI PG K +G G A GA PP P + + + +LG P G
Sbjct: 714 PGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG 772
Query: 432 ---ASGAGGAGGQAYSPGQ--------------------------PQGLLGPQ-----AY 457
GA G G S G+ P+G GP+ A
Sbjct: 773 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 832
Query: 458 GQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGP 517
G G Q K G P P P G + + GV G+P P
Sbjct: 833 PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG 892
Query: 518 AAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRP 577
G P S TG P G GG GP G GE P P+ P G P
Sbjct: 893 QRGPTG-PRGSRGARGPTG-KPGPKGTSGGDGPP--GPPGERGPQGPQGPVGFPGPKGPP 948
Query: 578 PGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK--GDGSELLAGPGGPPAER 635
G G PG PG G G++GK G + GP GP E
Sbjct: 949 GPPGKDGLPGH--------------PG----QRGETGFQGKTGPPGPGGVVGPQGPTGET 990
Query: 636 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAA--DASKGLGGSGGAGGPPGTPYELAKE 693
E + P PP G G G++GA +G+ G G G G P E
Sbjct: 991 GPIGE---RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL- 1046
Query: 694 DPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYG--- 750
GA A L +GGE P+G V G
Sbjct: 1047 ------------------PGAQGAPGL-------------KGGEGPQGPPGPVGSPGERG 1075
Query: 751 -AG-AKELGAFLQKSPP-PPPPTAQSTQPTPHGLLLEAG--GPDLPLVLPPPPPQLLPSV 805
AG A +G + P PP P + P G AG G P+ LP P
Sbjct: 1076 SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA------- 1128
Query: 806 LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS 865
P+ SP + EP + PP PP GL+ +
Sbjct: 1129 ---GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-------------GLQGPVGA 1172
Query: 866 PRLRPEESLDPPGAMQELLG-----ALEPLPPAPGDTGV----GPPNSEGKD----PAGA 912
P + + P Q + G P PG G+ GPP +G++ P G
Sbjct: 1173 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232
Query: 913 YRSPSPQGTKAPRFV-----PLTSICFPDSLLQ----DEERSFFPTMEEMFGG--GAADD 961
P P+G + P P S+ + + E + P E GG G +
Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1292
Query: 962 YGKAGPPEDEGDPKAGAGPP--------PGPPAYDPYGPYCPGRASGAGPETPGLGLDPN 1013
G+AGPP G P A GPP PGP + P P PG AG + G+G D
Sbjct: 1293 KGEAGPPGAAGPPGA-KGPPGDDGPKGNPGPVGF-PGDPGPPGEPGPAGQD--GVGGDKG 1348
Query: 1014 KPPELPSTVNAEPLGLIQSGPHQAAPPPPP----PPPPPPAPASEPKGGLTSPIFCSTKP 1069
+ + P G +A PP PP PP A + + G P
Sbjct: 1349 EDGDPGQPGPPGPSG-------EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1401
Query: 1070 KKLLKTSSFHLLRRRDPP--FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSS 1127
K + P P + Q A +D P + P LP L
Sbjct: 1402 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP----MGPPGLPGLKGD 1457
Query: 1128 CRSRPALSPLGDIDFCPPNPGPDGPR-RRGRKPTK----AKRD----GPPRPRGRPRIRP 1178
S+ G I P PG G + RG T+ AK D GP P G P P
Sbjct: 1458 PGSKGEKGHPGLIGLIGP-PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GP 1514
Query: 1179 LEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAG-GTRLEPLKPLKIKLSVPKAGEG 1237
+P GP G+ P G+ G G E ++PL I LS K
Sbjct: 1515 PGLPGPQGPKG----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI-LSSKKTRRH 1569
Query: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMK 1278
DA D N LD S E+I + +++ MK
Sbjct: 1570 TEGMQADA----DDNILDYSDGMEEIFGSLNSLKQDIEHMK 1606
Score = 101 bits (252), Expect = 7e-21
Identities = 330/1433 (23%), Positives = 440/1433 (30%), Gaps = 298/1433 (20%)
Query: 290 KHYQRPASAQP-----PPPPPPAHALQHYLSCGGSYPSMGHRANLAC--------SPLGG 336
K Y+ ++ P P P + ++ G+Y G + A P G
Sbjct: 399 KEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP 458
Query: 337 GEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
P+ G P GP+G G G P G GA G G ++ P G G
Sbjct: 459 AGPAGIMGPPGLQGPTGPP-GDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517
Query: 397 GAAAGG--------------ATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA 442
G A R PP T + +GGP G+ GA G++
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP----------GSSGAKGES 567
Query: 443 YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQL 502
PG PQG G Q GPP P P G P
Sbjct: 568 GDPG-PQGPRGVQ----------------------GPPGPTGKPGKRG-------RPGAD 597
Query: 503 QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSP----------ALSGHGGGWGPSS 552
G+ G+ GEP GLP + P + G G GP
Sbjct: 598 GGR--GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655
Query: 553 LGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGA 612
L G EA P ++ P +P A G+P G G PG + P PPG G
Sbjct: 656 LPG--EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP--GPPGQQGNP-GP 710
Query: 613 GGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASK 672
G G GP GPP E+ + P GADG G G +
Sbjct: 711 QGLPGP-------QGPIGPPGEKGPQGK---------PGLAGLPGADGPPGHPG----KE 750
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP 732
G G GA GPPG + P+ +GA L G EK +
Sbjct: 751 GQSGEKGALGPPGPQGPIGYPGPRGV-------------KGADGVRGLK-GSKGEKGEDG 796
Query: 733 ERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQST-QPTPHGLLLEAGGPDLP 791
G + GL G ++G + P P A T P P G E G +P
Sbjct: 797 FPGFKGDMGLKGDRGEVG----QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852
Query: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851
LP P + P + P + + G + G P P P P
Sbjct: 853 -GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA-----GKPGPRGQRGPTGPR------ 900
Query: 852 AHLRSHGLEPAAPSPRLRPEESLD-PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPA 910
S G P + D PPG E G P P GPP GKD
Sbjct: 901 ---GSRGARGPTGKPGPKGTSGGDGPPGPPGER-GPQGPQGPVGFPGPKGPPGPPGKD-- 954
Query: 911 GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPED 970
G P +G F T P ++ G G+ GP +
Sbjct: 955 GLPGHPGQRGETG--FQGKTGPPGPGGVV-----------------GPQGPTGETGPIGE 995
Query: 971 EGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI 1030
G P PPGPP P G+ G P + P L L
Sbjct: 996 RGHPG-----PPGPPGEQGL-PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1049
Query: 1031 QSGPH-QAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
Q P + P PP P +P G PI +P + PP
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP------------QGPPGP 1097
Query: 1090 TPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGP 1149
+K E + + V + L PA P G +PG
Sbjct: 1098 AGEKGAPGEKGPQGPAGRDGVQGPVGL-------------PGPA-GPAG-------SPGE 1136
Query: 1150 DG-------PRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRG 1202
DG P ++G K K + +GPP P G P+ P AG DG PRG
Sbjct: 1137 DGDKGEIGEPGQKGSKGDKGE-NGPPGPPGLQG--PVGAPGIAGG-------DGEPGPRG 1186
Query: 1203 RGRGRGRKAEEAGGTRLEPLKPLKIK-LSVPKAGEG-------------------LGTSS 1242
+ G+K +E P P+ ++ L P +G G +
Sbjct: 1187 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1246
Query: 1243 GDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAG 1302
D G + EK E E P ++G + + G+ PP G
Sbjct: 1247 ADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPKGERGEKGEAGPP----G 1300
Query: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPP----PSGAFGLGGALEAAESEGLGLG 1358
P P PP P P P P PP P+G G+GG + + + G
Sbjct: 1301 AAGP--PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD-KGEDGDPGQPG 1357
Query: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418
P P P + A+ R ++ A P GP
Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAG------AEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1411
Query: 1419 PDGPPLAPAA-AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPP- 1476
P G P +PGP GLP A P P+ PP P P + P
Sbjct: 1412 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---GPPGLPGLKGDPGSKGEKGHPG 1468
Query: 1477 ------PPQPALPSPPPLVAPTPSSP----------PPPPLPPPPPPAMPSPPPPP---- 1516
PP + T SP P PL PP PP +P P P
Sbjct: 1469 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528
Query: 1517 ---PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKK--QETAAVCGETDEEAGE--SG 1569
P + P P +P P E+ P+ +KK + T + + D+ + G
Sbjct: 1529 STGPAGQKGDSGLPGPPGSPGPPG-EVIQPLPILSSKKTRRHTEGMQADADDNILDYSDG 1587
Query: 1570 GEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
E IF + +DI +K + T P + LQ P+ DG+
Sbjct: 1588 MEEIFGSLNSL---KQDIEHMKFPMGTQTNPARTCKD----LQLSHPDFPDGE 1633
Score = 99.0 bits (245), Expect = 4e-20
Identities = 250/957 (26%), Positives = 303/957 (31%), Gaps = 220/957 (22%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GPAG PP GP PP P ++ P GA
Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPGDP-------------------GDRGPPGRPGLPGA 494
Query: 272 --APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHA----LQHYLSCGGSYPSMGH 325
PGPP LP + Y S P A A Q ++ G MG
Sbjct: 495 DGLPGPPGTMLMLPFR------YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 548
Query: 326 RANLACSPLGGGEPSPGAGEPSKAGPSG--------ATAGASGRATGPEAAGGGGAGG-- 375
P+GG S GE GP G G G+ P A GG G G
Sbjct: 549 TGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG--------GPAAAY 427
G G R PG KG G PP + +G GP
Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666
Query: 428 ATGKASGAGGAGGQA--YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSG 485
GA G G A P P+G +GP QG G Q + P G PQ P G
Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPG-PQGPIG 721
Query: 486 PP-------PPGLATC------QSYSPDQLQGQLYGVQGEP-------YPGPAAHSQGLP 525
PP PGLA + + Q G G P YPGP +G+
Sbjct: 722 PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP----RGVK 777
Query: 526 TAS--PSLSYSTGHS-----PALSGHGGGWGP----SSLGGGGEASPSHIIRPLQSPPAT 574
A L S G P G G G +G GE P P T
Sbjct: 778 GADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE---GPKGRAGPT 834
Query: 575 GRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAE 634
G P G G GK L P P + G G G+ G+ +AG GP +
Sbjct: 835 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE-KGARGVAGKPGPRGQ 893
Query: 635 RTEDEEFLIQHLLQAPSPPRTS-GADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKE 693
R P+ PR S GA G G+ G G+ G GPPG P E +
Sbjct: 894 R-------------GPTGPRGSRGARGPTGKPGPK-------GTSGGDGPPGPPGERGPQ 933
Query: 694 DPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGA 753
PQ +G GP +G P G H G
Sbjct: 934 GPQG---------------------PVGF-------PGP-KGPPGPPGKDGLPGHPGQRG 964
Query: 754 KELGAFLQKSPPPPPPTAQSTQPTPH-GLLLEAGGPDLPLVLPPPPPQLLPSVLSHA--- 809
E G + PP P PT G + E G P P PP Q LP
Sbjct: 965 -ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP---GPPGEQGLPGAAGKEGAK 1020
Query: 810 --PSPSPSASKVGVHLLE--PATR-----DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE 860
P P + K G L P R GAP P PP P+ S G
Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1080
Query: 861 -----PAAPSPRLRPEESLD--PPG-----------AMQELLGALEPLPPA--PGDTG-- 898
P P P+ P + + PG +Q +G P PA PG+ G
Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140
Query: 899 --VGPPNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFG 955
+G P +G K G P P G + P P + + + ++ F +E
Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200
Query: 956 G-----GAADDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPYCPGRASG-AGPE--- 1004
G G G GPP ++G+ GP PPGPP P GP P A G GP
Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGE-NGDVGPMGPPGPPG--PRGPQGPNGADGPQGPPGSV 1257
Query: 1005 ----------TPGLGLDPNKPPEL----PSTVNAEPLGLIQSGPHQAAPPPPPPPPP 1047
PG +P P E P E ++GP AA PP PP
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK---GEAGPPGAAGPPGAKGPP 1311
Score = 93.2 bits (230), Expect = 2e-18
Identities = 158/590 (26%), Positives = 186/590 (31%), Gaps = 119/590 (20%)
Query: 158 GSRPFPVPSSLSLQDPPFS----PPANGLLSPHDVLHLKPSQAPT-VPSSLGFERLAGG- 211
G++ P P +S +D P P GL LK + P P +G G
Sbjct: 1018 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1077
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GP GL P RPGP PP P A Q G
Sbjct: 1078 GTAGPIGL------PGRPGPQGPPGPA----------GEKGAPGEKGPQGPAGRDGVQGP 1121
Query: 272 A--PGPPPPERALPRQDTVIKHYQRPAS-------AQPPPPPPPAHALQHYLSCGGSYPS 322
PGP P + P +D P + PP PP LQ + G
Sbjct: 1122 VGLPGPAGPAGS-PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--LQGPVGAPGIAGG 1178
Query: 323 MGHRANLACSPLGGGEPSPGA-GEPSKAGPSG--------------ATAGASGRATGPEA 367
G + G + GA G P GP G G G P
Sbjct: 1179 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP 1238
Query: 368 AGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA--GGATRPPPPRSTAT--PKCQ----- 418
G G G G P PG GG G G A P PP PK +
Sbjct: 1239 RGPQGPNGADGPQGP----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG 1294
Query: 419 SLGGPAAAYATGKASGAGGAGGQAYSPGQ--------PQGLLGPQAYGQGFGGGQAQDLS 470
G P AA G A G G G +PG P G GP A G GG + +D
Sbjct: 1295 EAGPPGAAGPPG-AKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP-AGQDGVGGDKGEDGD 1352
Query: 471 KA------PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGL 524
PS GPP PP PPG A + ++ G +G P QG
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG- 1411
Query: 525 PTASPSLSYSTGHSPALSGHGGGWGPSSL-GGGGEASPSHIIRPLQSPPATGRPPGVGSP 583
P P L G G G L G G+ P + P P G P G
Sbjct: 1412 PAGKPG-------PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1464
Query: 584 GAPGKYLSSVLASAPFLAPPGAGSYAAGAG--GYKG----KGDGSELLAGPGGPPAERTE 637
G PG + PPG G G +G KGDG + GP GP
Sbjct: 1465 GHPGLI--------GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG--IPGPAGP------ 1508
Query: 638 DEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP 687
L P PP G G G G+ + G G G GPPG+P
Sbjct: 1509 ---------LGPPGPPGLPGPQGPKGNKGSTGPA-GQKGDSGLPGPPGSP 1548
Score = 38.5 bits (88), Expect = 0.068
Identities = 42/171 (24%), Positives = 61/171 (35%), Gaps = 23/171 (13%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPE--------QTPET 1721
PP PV G+ + +AG P P PP P + EK P+ Q P
Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP-V 1122
Query: 1722 AMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRL 1781
+P P P P E + E G++ +G++ +G P G P +
Sbjct: 1123 GLPGPAGPAG----SPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA-- 1176
Query: 1782 PKARPTKVKAEPPPKKRKKWLKEAGGNATAG-GGPPGSSSDSESSPGAPSE 1831
EP P+ ++ + G G GPPG + PG P E
Sbjct: 1177 ------GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG-LQGLPGPPGE 1220
Score = 38.5 bits (88), Expect = 0.068
Identities = 45/178 (25%), Positives = 58/178 (32%), Gaps = 13/178 (7%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P+ G P G + P P PP P P+ P+ P +
Sbjct: 1205 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1264
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
EK E G + RGE+ +G A G P PK P V
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPV 1323
Query: 1790 ----KAEPPPKKRKKWLKEAGGNATAGG-----GPPGSSSDSESSPGAPSEDERAVPG 1838
PP + GG+ G GPPG S ++ PG P +R PG
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA-GPPGPPG--KRGPPG 1378
Score = 37.4 bits (85), Expect = 0.15
Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 9/188 (4%)
Query: 1345 GALEAAESEG----LGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
G +E+ ++E G P+P + + E E S + ED++ +N+++ S
Sbjct: 324 GTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSD 383
Query: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAV-PGPPPLPGLPSANSNGTPEPPLLEEKPPP 1459
+ D + D P P PG P + + NG EK
Sbjct: 384 LLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGA---YGEKGQK 440
Query: 1460 TPPPAPTPQPQPPPPPPPPQPA-LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
P P PP P PA + PP L PT P PP P +P P P
Sbjct: 441 GEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP 500
Query: 1519 AAAPLAAP 1526
L P
Sbjct: 501 PGTMLMLP 508
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 108 bits (270), Expect = 5e-23
Identities = 210/794 (26%), Positives = 254/794 (31%), Gaps = 173/794 (21%)
Query: 163 PVPSSLSLQDPPFSPPAN-GLLSPHDVLHLKPSQAPTVP-------------SSLGFERL 208
P P S D P PP G P + + P P GF+
Sbjct: 861 PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 920
Query: 209 AG----GGVLGPAGLGPAQTPPYRPGPPDPPPPP--RHLPTQFNLLASSSAAAAAAEQSS 262
G GGV+GP G P G P PP PP + LP AA +
Sbjct: 921 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP---------GAAGKEGAKGD 971
Query: 263 PQLYNFSGAAPGPP-----PPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCG 317
P SG GP P ER LP P PP P + S G
Sbjct: 972 PGPQGISG-KDGPAGLRGFPGERGLPGAQGA---PGLKGGEGPQGPPGPVGSPGERGSAG 1027
Query: 318 GSYPSMGHRANLACSPLGGGEPSPGA--GEPSKAGPSGATA--GASGRATGPEAAGGGGA 373
+ P L P G P P G P + GP G G G P AG G+
Sbjct: 1028 TAGP-----IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082
Query: 374 GGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKAS 433
G G + I PG K KG G PP P P +G P A G+
Sbjct: 1083 PGEDGD-KGEIGEPGQKGSKGD-----KGENGPPGPPGLQGP----VGAPGIAGGDGEPG 1132
Query: 434 GAGGAG--------GQAYSPGQP-----QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPP 480
G G G PG P QGL GP G + ++ P GPP
Sbjct: 1133 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP-------GEKGENGDVGPMGPPGPP 1185
Query: 481 QPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPA 540
P GP P A P + G + GV + PG A +P
Sbjct: 1186 -GPRGPQGPNGADGPQGPPGSV-GSVGGVGEKGEPGEAG------------------NPG 1225
Query: 541 LSGHGGGWGP-SSLGGGGEASPSHIIRP--LQSPPA----TGRPPGVGSPGAPGKYLSSV 593
G G GP G GEA P P + PP G P VG PG PG
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG------ 1279
Query: 594 LASAPFLAPPGAGSYAA--GAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPS 651
PPG A G GG KG+ DG GP GP E P
Sbjct: 1280 --------PPGEPGPAGQDGVGGDKGE-DGDPGQPGPPGPSGE------------AGPPG 1318
Query: 652 PPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIR--TSAS 709
PP G G G +G KG G GA GPPG + + P +R
Sbjct: 1319 PPGKRGPPGAAGAEG-RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377
Query: 710 LDEGATAAL-------ELGLGRLKEKKKGPERGGETPE-GLATSVVHYGAGAKELGAFLQ 761
++G A +G L K P GE GL + G ++ L
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
Query: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGV 821
+ P P P G L G P LP P P+ + S P+ K
Sbjct: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLP---GPQGPK------GNKGSTGPAGQK--- 1485
Query: 822 HLLEPATRDGAPQPPPPPPPPP---PPMPLQLEAHLRSH--GLEPAAPSPRLRPEESLDP 876
G P PP P PP P+P+ R H G++ A + LD
Sbjct: 1486 ------GDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA------DDNILDY 1533
Query: 877 PGAMQELLGALEPL 890
M+E+ G+L L
Sbjct: 1534 SDGMEEIFGSLNSL 1547
Score = 105 bits (263), Expect = 3e-22
Identities = 309/1241 (24%), Positives = 396/1241 (31%), Gaps = 259/1241 (20%)
Query: 174 PFSPPANGLLSPHDVLHLKP-------SQAPTVPSS-------LGFERLAGGGVLGPAGL 219
P P A+GL P + + P S+ PT+ + L R+A G GP GL
Sbjct: 438 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 497
Query: 220 ----GPAQTPPYR--------PGPPDP-----PPPPRHLPTQFNLLASSSAAAAAAEQSS 262
GP P PGP P PP P P + + E +
Sbjct: 498 TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557
Query: 263 PQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS 322
F G PG P K ++ Q PP PP ++ G
Sbjct: 558 KGDRGFDGL-PGLPGD-----------KGHRGERGPQGPPGPPGDDGMRGE---DGEIGP 602
Query: 323 MGHRANLACSPLGGGEPSPGA-GEPSKAGPSG-----ATAGASGRATGPEAAGGGGAGGG 376
G L G +PGA G+P AG G G G P G G G
Sbjct: 603 RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 662
Query: 377 GGGYRPIIQSPGYKTGKGGYGAAA-GGATRPP--PPRSTATPKCQSLGGPAAAYATGK-- 431
G PI PG K +G G A GA PP P + + + +LG P G
Sbjct: 663 PGPQGPI-GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG 721
Query: 432 ---ASGAGGAGGQAYSPGQ--------------------------PQGLLGPQ-----AY 457
GA G G S G+ P+G GP+ A
Sbjct: 722 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAG 781
Query: 458 GQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGP 517
G G Q K G P P P G + + GV G+P P
Sbjct: 782 PTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG 841
Query: 518 AAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRP 577
G P S TG P G GG GP G GE P P+ P G P
Sbjct: 842 QRGPTG-PRGSRGARGPTG-KPGPKGTSGGDGPP--GPPGERGPQGPQGPVGFPGPKGPP 897
Query: 578 PGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK--GDGSELLAGPGGPPAER 635
G G PG PG G G++GK G + GP GP E
Sbjct: 898 GPPGKDGLPGH--------------PG----QRGETGFQGKTGPPGPGGVVGPQGPTGET 939
Query: 636 TEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAA--DASKGLGGSGGAGGPPGTPYELAKE 693
E + P PP G G G++GA +G+ G G G G P E
Sbjct: 940 GPIGE---RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL- 995
Query: 694 DPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYG--- 750
GA A L +GGE P+G V G
Sbjct: 996 ------------------PGAQGAPGL-------------KGGEGPQGPPGPVGSPGERG 1024
Query: 751 -AG-AKELGAFLQKSPP-PPPPTAQSTQPTPHGLLLEAG--GPDLPLVLPPPPPQLLPSV 805
AG A +G + P PP P + P G AG G P+ LP P
Sbjct: 1025 SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA------- 1077
Query: 806 LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS 865
P+ SP + EP + PP PP GL+ +
Sbjct: 1078 ---GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP-------------GLQGPVGA 1121
Query: 866 PRLRPEESLDPPGAMQELLG-----ALEPLPPAPGDTGV----GPPNSEGKD----PAGA 912
P + + P Q + G P PG G+ GPP +G++ P G
Sbjct: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
Query: 913 YRSPSPQGTKAPRFV-----PLTSICFPDSLLQ----DEERSFFPTMEEMFGG--GAADD 961
P P+G + P P S+ + + E + P E GG G +
Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
Query: 962 YGKAGPPEDEGDPKAGAGPP--------PGPPAYDPYGPYCPGRASGAGPETPGLGLDPN 1013
G+AGPP G P A GPP PGP + P P PG AG + G+G D
Sbjct: 1242 KGEAGPPGAAGPPGA-KGPPGDDGPKGNPGPVGF-PGDPGPPGEPGPAGQD--GVGGDKG 1297
Query: 1014 KPPELPSTVNAEPLGLIQSGPHQAAPPPPP----PPPPPPAPASEPKGGLTSPIFCSTKP 1069
+ + P G +A PP PP PP A + + G P
Sbjct: 1298 EDGDPGQPGPPGPSG-------EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1350
Query: 1070 KKLLKTSSFHLLRRRDPP--FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSS 1127
K + P P + Q A +D P + P LP L
Sbjct: 1351 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP----MGPPGLPGLKGD 1406
Query: 1128 CRSRPALSPLGDIDFCPPNPGPDGPR-RRGRKPTK----AKRD----GPPRPRGRPRIRP 1178
S+ G I P PG G + RG T+ AK D GP P G P P
Sbjct: 1407 PGSKGEKGHPGLIGLIGP-PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GP 1463
Query: 1179 LEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAG-GTRLEPLKPLKIKLSVPKAGEG 1237
+P GP G+ P G+ G G E ++PL I LS K
Sbjct: 1464 PGLPGPQGPKG----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI-LSSKKTRRH 1518
Query: 1238 LGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMK 1278
DA D N LD S E+I + +++ MK
Sbjct: 1519 TEGMQADA----DDNILDYSDGMEEIFGSLNSLKQDIEHMK 1555
Score = 101 bits (252), Expect = 7e-21
Identities = 330/1433 (23%), Positives = 440/1433 (30%), Gaps = 298/1433 (20%)
Query: 290 KHYQRPASAQP-----PPPPPPAHALQHYLSCGGSYPSMGHRANLAC--------SPLGG 336
K Y+ ++ P P P + ++ G+Y G + A P G
Sbjct: 348 KEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP 407
Query: 337 GEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY 396
P+ G P GP+G G G P G GA G G ++ P G G
Sbjct: 408 AGPAGIMGPPGLQGPTGPP-GDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466
Query: 397 GAAAGG--------------ATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA 442
G A R PP T + +GGP G+ GA G++
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP----------GSSGAKGES 516
Query: 443 YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQL 502
PG PQG G Q GPP P P G P
Sbjct: 517 GDPG-PQGPRGVQ----------------------GPPGPTGKPGKRG-------RPGAD 546
Query: 503 QGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSP----------ALSGHGGGWGPSS 552
G+ G+ GEP GLP + P + G G GP
Sbjct: 547 GGR--GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604
Query: 553 LGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGA 612
L G EA P ++ P +P A G+P G G PG + P PPG G
Sbjct: 605 LPG--EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP--GPPGQQGNP-GP 659
Query: 613 GGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASK 672
G G GP GPP E+ + P GADG G G +
Sbjct: 660 QGLPGP-------QGPIGPPGEKGPQGK---------PGLAGLPGADGPPGHPG----KE 699
Query: 673 GLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGP 732
G G GA GPPG + P+ +GA L G EK +
Sbjct: 700 GQSGEKGALGPPGPQGPIGYPGPRGV-------------KGADGVRGLK-GSKGEKGEDG 745
Query: 733 ERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQST-QPTPHGLLLEAGGPDLP 791
G + GL G ++G + P P A T P P G E G +P
Sbjct: 746 FPGFKGDMGLKGDRGEVG----QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801
Query: 792 LVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLE 851
LP P + P + P + + G + G P P P P
Sbjct: 802 -GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA-----GKPGPRGQRGPTGPR------ 849
Query: 852 AHLRSHGLEPAAPSPRLRPEESLD-PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPA 910
S G P + D PPG E G P P GPP GKD
Sbjct: 850 ---GSRGARGPTGKPGPKGTSGGDGPPGPPGER-GPQGPQGPVGFPGPKGPPGPPGKD-- 903
Query: 911 GAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPED 970
G P +G F T P ++ G G+ GP +
Sbjct: 904 GLPGHPGQRGETG--FQGKTGPPGPGGVV-----------------GPQGPTGETGPIGE 944
Query: 971 EGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLI 1030
G P PPGPP P G+ G P + P L L
Sbjct: 945 RGHPG-----PPGPPGEQGL-PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 998
Query: 1031 QSGPH-QAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQ 1089
Q P + P PP P +P G PI +P + PP
Sbjct: 999 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP------------QGPPGP 1046
Query: 1090 TPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGP 1149
+K E + + V + L PA P G +PG
Sbjct: 1047 AGEKGAPGEKGPQGPAGRDGVQGPVGL-------------PGPA-GPAG-------SPGE 1085
Query: 1150 DG-------PRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRG 1202
DG P ++G K K + +GPP P G P+ P AG DG PRG
Sbjct: 1086 DGDKGEIGEPGQKGSKGDKGE-NGPPGPPGLQG--PVGAPGIAGG-------DGEPGPRG 1135
Query: 1203 RGRGRGRKAEEAGGTRLEPLKPLKIK-LSVPKAGEG-------------------LGTSS 1242
+ G+K +E P P+ ++ L P +G G +
Sbjct: 1136 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1195
Query: 1243 GDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAG 1302
D G + EK E E P ++G + + G+ PP G
Sbjct: 1196 ADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPKGERGEKGEAGPP----G 1249
Query: 1303 LTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPP----PSGAFGLGGALEAAESEGLGLG 1358
P P PP P P P P PP P+G G+GG + + + G
Sbjct: 1250 AAGP--PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD-KGEDGDPGQPG 1306
Query: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTST 1418
P P P + A+ R ++ A P GP
Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAG------AEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1360
Query: 1419 PDGPPLAPAA-AVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPP- 1476
P G P +PGP GLP A P P+ PP P P + P
Sbjct: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---GPPGLPGLKGDPGSKGEKGHPG 1417
Query: 1477 ------PPQPALPSPPPLVAPTPSSP----------PPPPLPPPPPPAMPSPPPPP---- 1516
PP + T SP P PL PP PP +P P P
Sbjct: 1418 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477
Query: 1517 ---PPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKK--QETAAVCGETDEEAGE--SG 1569
P + P P +P P E+ P+ +KK + T + + D+ + G
Sbjct: 1478 STGPAGQKGDSGLPGPPGSPGPPG-EVIQPLPILSSKKTRRHTEGMQADADDNILDYSDG 1536
Query: 1570 GEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQ 1622
E IF + +DI +K + T P + LQ P+ DG+
Sbjct: 1537 MEEIFGSLNSL---KQDIEHMKFPMGTQTNPARTCKD----LQLSHPDFPDGE 1582
Score = 99.0 bits (245), Expect = 4e-20
Identities = 250/957 (26%), Positives = 303/957 (31%), Gaps = 220/957 (22%)
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GPAG PP GP PP P ++ P GA
Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPGDP-------------------GDRGPPGRPGLPGA 443
Query: 272 --APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHA----LQHYLSCGGSYPSMGH 325
PGPP LP + Y S P A A Q ++ G MG
Sbjct: 444 DGLPGPPGTMLMLPFR------YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 497
Query: 326 RANLACSPLGGGEPSPGAGEPSKAGPSG--------ATAGASGRATGPEAAGGGGAGG-- 375
P+GG S GE GP G G G+ P A GG G G
Sbjct: 498 TGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555
Query: 376 GGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLG--------GPAAAY 427
G G R PG KG G PP + +G GP
Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615
Query: 428 ATGKASGAGGAGGQA--YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSG 485
GA G G A P P+G +GP QG G Q + P G PQ P G
Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGP----QGEPGPPGQQGNPGPQGLPG-PQGPIG 670
Query: 486 PP-------PPGLATC------QSYSPDQLQGQLYGVQGEP-------YPGPAAHSQGLP 525
PP PGLA + + Q G G P YPGP +G+
Sbjct: 671 PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGP----RGVK 726
Query: 526 TAS--PSLSYSTGHS-----PALSGHGGGWGP----SSLGGGGEASPSHIIRPLQSPPAT 574
A L S G P G G G +G GE P P T
Sbjct: 727 GADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE---GPKGRAGPT 783
Query: 575 GRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAE 634
G P G G GK L P P + G G G+ G+ +AG GP +
Sbjct: 784 GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE-KGARGVAGKPGPRGQ 842
Query: 635 RTEDEEFLIQHLLQAPSPPRTS-GADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKE 693
R P+ PR S GA G G+ G G+ G GPPG P E +
Sbjct: 843 R-------------GPTGPRGSRGARGPTGKPGPK-------GTSGGDGPPGPPGERGPQ 882
Query: 694 DPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGA 753
PQ +G GP +G P G H G
Sbjct: 883 GPQG---------------------PVGF-------PGP-KGPPGPPGKDGLPGHPGQRG 913
Query: 754 KELGAFLQKSPPPPPPTAQSTQPTPH-GLLLEAGGPDLPLVLPPPPPQLLPSVLSHA--- 809
E G + PP P PT G + E G P P PP Q LP
Sbjct: 914 -ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP---GPPGEQGLPGAAGKEGAK 969
Query: 810 --PSPSPSASKVGVHLLE--PATR-----DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE 860
P P + K G L P R GAP P PP P+ S G
Sbjct: 970 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1029
Query: 861 -----PAAPSPRLRPEESLD--PPG-----------AMQELLGALEPLPPA--PGDTG-- 898
P P P+ P + + PG +Q +G P PA PG+ G
Sbjct: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089
Query: 899 --VGPPNSEG-KDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFG 955
+G P +G K G P P G + P P + + + ++ F +E
Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149
Query: 956 G-----GAADDYGKAGPPEDEGDPKAGAGP--PPGPPAYDPYGPYCPGRASG-AGPE--- 1004
G G G GPP ++G+ GP PPGPP P GP P A G GP
Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGE-NGDVGPMGPPGPPG--PRGPQGPNGADGPQGPPGSV 1206
Query: 1005 ----------TPGLGLDPNKPPEL----PSTVNAEPLGLIQSGPHQAAPPPPPPPPP 1047
PG +P P E P E ++GP AA PP PP
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK---GEAGPPGAAGPPGAKGPP 1260
Score = 93.2 bits (230), Expect = 2e-18
Identities = 158/590 (26%), Positives = 186/590 (31%), Gaps = 119/590 (20%)
Query: 158 GSRPFPVPSSLSLQDPPFS----PPANGLLSPHDVLHLKPSQAPT-VPSSLGFERLAGG- 211
G++ P P +S +D P P GL LK + P P +G G
Sbjct: 967 GAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSA 1026
Query: 212 GVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
G GP GL P RPGP PP P A Q G
Sbjct: 1027 GTAGPIGL------PGRPGPQGPPGPA----------GEKGAPGEKGPQGPAGRDGVQGP 1070
Query: 272 A--PGPPPPERALPRQDTVIKHYQRPAS-------AQPPPPPPPAHALQHYLSCGGSYPS 322
PGP P + P +D P + PP PP LQ + G
Sbjct: 1071 VGLPGPAGPAGS-PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--LQGPVGAPGIAGG 1127
Query: 323 MGHRANLACSPLGGGEPSPGA-GEPSKAGPSG--------------ATAGASGRATGPEA 367
G + G + GA G P GP G G G P
Sbjct: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGP 1187
Query: 368 AGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA--GGATRPPPPRSTAT--PKCQ----- 418
G G G G P PG GG G G A P PP PK +
Sbjct: 1188 RGPQGPNGADGPQGP----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG 1243
Query: 419 SLGGPAAAYATGKASGAGGAGGQAYSPGQ--------PQGLLGPQAYGQGFGGGQAQDLS 470
G P AA G A G G G +PG P G GP A G GG + +D
Sbjct: 1244 EAGPPGAAGPPG-AKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP-AGQDGVGGDKGEDGD 1301
Query: 471 KA------PSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGL 524
PS GPP PP PPG A + ++ G +G P QG
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG- 1360
Query: 525 PTASPSLSYSTGHSPALSGHGGGWGPSSL-GGGGEASPSHIIRPLQSPPATGRPPGVGSP 583
P P L G G G L G G+ P + P P G P G
Sbjct: 1361 PAGKPG-------PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413
Query: 584 GAPGKYLSSVLASAPFLAPPGAGSYAAGAG--GYKG----KGDGSELLAGPGGPPAERTE 637
G PG + PPG G G +G KGDG + GP GP
Sbjct: 1414 GHPGLI--------GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG--IPGPAGP------ 1457
Query: 638 DEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTP 687
L P PP G G G G+ + G G G GPPG+P
Sbjct: 1458 ---------LGPPGPPGLPGPQGPKGNKGSTGPA-GQKGDSGLPGPPGSP 1497
Score = 38.5 bits (88), Expect = 0.068
Identities = 42/171 (24%), Positives = 61/171 (35%), Gaps = 23/171 (13%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPE--------QTPET 1721
PP PV G+ + +AG P P PP P + EK P+ Q P
Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP-V 1071
Query: 1722 AMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRL 1781
+P P P P E + E G++ +G++ +G P G P +
Sbjct: 1072 GLPGPAGPAG----SPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA-- 1125
Query: 1782 PKARPTKVKAEPPPKKRKKWLKEAGGNATAG-GGPPGSSSDSESSPGAPSE 1831
EP P+ ++ + G G GPPG + PG P E
Sbjct: 1126 ------GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG-LQGLPGPPGE 1169
Score = 38.5 bits (88), Expect = 0.068
Identities = 45/178 (25%), Positives = 58/178 (32%), Gaps = 13/178 (7%)
Query: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
PP P+ G P G + P P PP P P+ P+ P +
Sbjct: 1154 PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVG 1213
Query: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
EK E G + RGE+ +G A G P PK P V
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPV 1272
Query: 1790 ----KAEPPPKKRKKWLKEAGGNATAGG-----GPPGSSSDSESSPGAPSEDERAVPG 1838
PP + GG+ G GPPG S ++ PG P +R PG
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEA-GPPGPPG--KRGPPG 1327
Score = 37.4 bits (85), Expect = 0.15
Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 9/188 (4%)
Query: 1345 GALEAAESEG----LGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
G +E+ ++E G P+P + + E E S + ED++ +N+++ S
Sbjct: 273 GTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSD 332
Query: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAV-PGPPPLPGLPSANSNGTPEPPLLEEKPPP 1459
+ D + D P P PG P + + NG EK
Sbjct: 333 LLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGA---YGEKGQK 389
Query: 1460 TPPPAPTPQPQPPPPPPPPQPA-LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
P P PP P PA + PP L PT P PP P +P P P
Sbjct: 390 GEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP 449
Query: 1519 AAAPLAAP 1526
L P
Sbjct: 450 PGTMLMLP 457
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 138,245,653
Number of Sequences: 37866
Number of extensions: 12003521
Number of successful extensions: 389708
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2301
Number of HSP's successfully gapped in prelim test: 2494
Number of HSP's that attempted gapping in prelim test: 62245
Number of HSP's gapped (non-prelim): 137126
length of query: 2036
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1918
effective length of database: 13,779,330
effective search space: 26428754940
effective search space used: 26428754940
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.