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Search of human proteins with 149158690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
(2157 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 4522 0.0
gi|149192855 HLA-B associated transcript 2-like [Homo sapiens] 710 0.0
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 503 e-141
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 155 3e-37
gi|163965366 nascent polypeptide-associated complex alpha subuni... 154 7e-37
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 152 4e-36
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 146 2e-34
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 143 2e-33
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 142 3e-33
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 142 3e-33
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 137 1e-31
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 129 2e-29
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 129 2e-29
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 129 2e-29
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 129 3e-29
gi|47132519 Ras association and pleckstrin homology domains 1 is... 124 1e-27
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 123 2e-27
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 122 4e-27
gi|110349719 titin isoform N2-A [Homo sapiens] 122 5e-27
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 119 2e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 119 2e-26
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 119 4e-26
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 118 7e-26
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 117 9e-26
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 117 9e-26
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 116 3e-25
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 115 5e-25
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 115 5e-25
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 114 8e-25
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 110 1e-23
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 4523 bits (11730), Expect = 0.0
Identities = 2157/2157 (100%), Positives = 2157/2157 (100%)
Query: 1 MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA 60
MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA
Sbjct: 1 MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA 60
Query: 61 NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN 120
NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN
Sbjct: 61 NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN 120
Query: 121 QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD 180
QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD
Sbjct: 121 QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD 180
Query: 181 KAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGP 240
KAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGP
Sbjct: 181 KAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGP 240
Query: 241 PQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEP 300
PQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEP
Sbjct: 241 PQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEP 300
Query: 301 VGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRD 360
VGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRD
Sbjct: 301 VGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRD 360
Query: 361 SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA 420
SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA
Sbjct: 361 SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA 420
Query: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE 480
GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE
Sbjct: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE 480
Query: 481 ERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAP 540
ERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAP
Sbjct: 481 ERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAP 540
Query: 541 TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE
Sbjct: 541 TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
Query: 601 PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660
PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ
Sbjct: 601 PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660
Query: 661 QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD 720
QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD
Sbjct: 661 QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD 720
Query: 721 PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER
Sbjct: 721 PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
Query: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG
Sbjct: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
Query: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGR 900
FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGR
Sbjct: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGR 900
Query: 901 KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTK 960
KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTK
Sbjct: 901 KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTK 960
Query: 961 VEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP 1020
VEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP
Sbjct: 961 VEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP 1020
Query: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080
TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR
Sbjct: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080
Query: 1081 GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP 1140
GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP
Sbjct: 1081 GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP 1140
Query: 1141 PPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG 1200
PPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG
Sbjct: 1141 PPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG 1200
Query: 1201 PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRL 1260
PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRL
Sbjct: 1201 PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRL 1260
Query: 1261 KQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE 1320
KQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE
Sbjct: 1261 KQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE 1320
Query: 1321 WETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDL 1380
WETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDL
Sbjct: 1321 WETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDL 1380
Query: 1381 SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRS 1440
SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRS
Sbjct: 1381 SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRS 1440
Query: 1441 RPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK 1500
RPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK
Sbjct: 1441 RPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK 1500
Query: 1501 PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKR 1560
PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKR
Sbjct: 1501 PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKR 1560
Query: 1561 RERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSR 1620
RERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSR
Sbjct: 1561 RERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSR 1620
Query: 1621 KSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAA 1680
KSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAA
Sbjct: 1621 KSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAA 1680
Query: 1681 EGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQR 1740
EGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQR
Sbjct: 1681 EGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQR 1740
Query: 1741 TDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWE 1800
TDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWE
Sbjct: 1741 TDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWE 1800
Query: 1801 LLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPN 1860
LLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPN
Sbjct: 1801 LLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPN 1860
Query: 1861 SGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV 1920
SGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV
Sbjct: 1861 SGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV 1920
Query: 1921 LYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQML 1980
LYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQML
Sbjct: 1921 LYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQML 1980
Query: 1981 LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARP 2040
LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARP
Sbjct: 1981 LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARP 2040
Query: 2041 FPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV 2100
FPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV
Sbjct: 2041 FPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV 2100
Query: 2101 FRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
FRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPPR
Sbjct: 2101 FRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
>gi|149192855 HLA-B associated transcript 2-like [Homo sapiens]
Length = 2229
Score = 710 bits (1832), Expect = 0.0
Identities = 731/2296 (31%), Positives = 957/2296 (41%), Gaps = 491/2296 (21%)
Query: 1 MSDRSGPTAKGKDGK-KYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPP 59
MSDR G KGKDGK KYS+L+LFD YKGKS++ + +V PRHGLQSLGKVA ARRMPPP
Sbjct: 1 MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSVDAIRSSVIPRHGLQSLGKVAAARRMPPP 60
Query: 60 ANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPAS 119
ANLPSLK+ENKGNDPN+ +VPKDGTGWA+KQ+Q DPKSS A+ +QPPES P P Q S
Sbjct: 61 ANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSATASQPPESLPQPGLQKSVS 120
Query: 120 N-QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGD 178
N Q + ENT VP G KSWAQ + H G R SS L FS EEFPTL+AAG
Sbjct: 121 NLQKPTQSISQENTNSVPGGPKSWAQLNGKPVGHEGGLRGSSRLLSFSPEEFPTLKAAGG 180
Query: 179 QDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGR----------GPDELEGPDSKLHHG 228
QDKA KE+ + S GPGPSLRPQN T+WR+GGGR P EL +S G
Sbjct: 181 QDKAGKEKGVLDLSYGPGPSLRPQNVTSWREGGGRHIISATSLSTSPTELGSRNSSTGDG 240
Query: 229 ----------HDP---------RGGLQPSGPPQFPP-YRGMMPPFMYPPYL--------- 259
DP +G Q G PP Y M+P FM P
Sbjct: 241 APSSACTSDSKDPSLRPAQPVRKGASQFMGNVYHPPTYHDMLPAFMCSPKSSENQGTVER 300
Query: 260 -PFPPP---YGPQGPYR-YPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKE 314
FP P P+ P+R + D + R+ R P +LVE RP+I+ +NLK
Sbjct: 301 GSFPLPQLRLEPRVPFRQFQMNDQDGKENRLGLSRPLRPLRQLVERAPRPTIINAENLKG 360
Query: 315 FDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEAD 374
D LD + DDGWAG HEEVDY+EKLKFSD+E+ +EE + R ++ R +
Sbjct: 361 LDDLDADADDGWAGLHEEVDYSEKLKFSDDEE----EEEVVKDGRPKWNSWDPRRQRQLS 416
Query: 375 GKKGNSPNSEPPTPK-TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRG 433
+S +++ + WAE P P+PP H W P DY
Sbjct: 417 MSSADSADAKRTREEGKDWAEAVGASRVVRKAPDPQPPPRKLH-----GWAPGPDYQKSS 471
Query: 434 -GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKR 492
G + + ED+++ R+K SE+S AVERAR+RREEEERR +EER AACA KLK+
Sbjct: 472 MGSMFRQQSIEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRAREERLAACAAKLKQ 531
Query: 493 LDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQA 552
LD+K K +A A P +P+ A P+E P +PE
Sbjct: 532 LDQKCKQARKAGEARKQAEKEVPWSPSAEKASPQE-----NGPAVHKGSPEF-------- 578
Query: 553 PPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPP 612
PAQ TPT APT+ S + S S E E P++E
Sbjct: 579 -PAQETPTTFPEEAPTV-----SPAVAQSNSSEEEAREAGSPAQEF-------------- 618
Query: 613 VPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
KYQKSLPPRFQRQQQ+Q QQ+Q QH Q
Sbjct: 619 -------------------------KYQKSLPPRFQRQQQQQ---QQEQLYKMQHWQ--- 647
Query: 673 PPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDP 732
P PPS PQ + YP P M + FDPRWMM+P Y+DP
Sbjct: 648 -PVYPPPSHPQ-----------------RTFYP----HHPQM--LGFDPRWMMMPSYMDP 683
Query: 733 RLLQGRPPLDFYPPGVHPSGL----VPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPK 788
R+ R P+DFYP +HPSGL +P+E + G SE D++ L+ER P+D
Sbjct: 684 RITPTRTPVDFYPSALHPSGLMKPMMPQESLNGTGCRSE--DQNCVPPLQERKVTPIDSP 741
Query: 789 LAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPG 848
W + + A ++ PL P D +R+E+ + AS A G
Sbjct: 742 PVWSPEGYMALQSKGYPLPHPKSSDTLAMDMRVRNES-------SFSASL-----GRAGG 789
Query: 849 PPISRFPLEEPGP------------------------RPLPWPPGSDEVAKIQTP----- 879
R EE G + L +PP + V P
Sbjct: 790 VSAQRDLFEERGEEYLSAFDKKAQADFDSCISSQRIGQELLFPP-QENVQDAGAPGGHTQ 848
Query: 880 ------------PPKKEPP--------KEETAQLTGPEAGRKPARG----VGSGGQGPPP 915
P +K+P + ETA P G + S + P
Sbjct: 849 NLRCSPLEPDFVPDEKKPECGSWDVSHQPETADTAHGVERETPREGTAFNISSWDKNGSP 908
Query: 916 PRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKP-----PPPTKVEELPPKPLE 970
++ S +E W P P SS PE+ G RR+GPIKKP K +EL E
Sbjct: 909 NKQPS-SEPEWTPEPRSS-SSQHPEQTGR-TRRSGPIKKPVLKALKVEDKEKELEKIKQE 965
Query: 971 QGDETPKPPKPDPLKITKGK---------LGGPKET------------------------ 997
G+E+ + K T K L T
Sbjct: 966 LGEESTRLAKEKEQSPTAEKDEDEENDASLANSSTTTLEDKGPGHATFGREATKFEEEEK 1025
Query: 998 --------PPNGNLSPAPRLRRDYSY-ERVGPTSCRGRGRGEYFARGRGFR--------- 1039
PP + P R ++ + + RG+ RG RGRGFR
Sbjct: 1026 PDKAWEARPPRESSDVPPMKRNNWIFIDEEQAFGVRGQARG----RGRGFREFTFRGRPA 1081
Query: 1040 -----GTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEY 1094
G GG GARS S R RG R PR R ASET SEGSEY
Sbjct: 1082 GGNGSGLCGGGVLGARSIYCSSQRSGRGRGLREFARPEDCPRAKPRRRVASETHSEGSEY 1141
Query: 1095 EEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFT 1154
EE+PKRRRQRGSE G+E + ++E T K+G + S A+
Sbjct: 1142 EELPKRRRQRGSENGNEG-----SLLEREESTLKKGDCRDSWRSNKGCSEDHSGLDAK-- 1194
Query: 1155 ARGGRVFTPRGVPSRRGRGGGRPP--PQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEK 1212
+RG R F P G GR + P W + + ++ S+ P
Sbjct: 1195 SRGPRAFGRALPPRLSNCGYGRRTFVSKESPHWQSKSPGSSWQEYGPSDTCGSRRPTDRD 1254
Query: 1213 LIPGPLSPVARGGSNGGSNVGMED----------------GERPRRRRHGRAQQQDKPPR 1256
+P G G + ED RP RRR R +QDKPPR
Sbjct: 1255 YVPDSYRHPDAFGGRGFEDSRAEDKRSFFQDEHVADSENAENRPFRRR--RPPRQDKPPR 1312
Query: 1257 FRRLKQERENAAR-GSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQN-S 1314
FRRL+QERE+ G E +P L L PG + + RR SP+LS QN S
Sbjct: 1313 FRRLRQERESLGLWGPEEEPHL-LAGQWPGRPKLCSGDKSGTVGRR----SPELSYQNSS 1367
Query: 1315 DQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLS 1374
D ANEEWETASESSDF SERR +E P P G G+S S G+
Sbjct: 1368 DHANEEWETASESSDF-SERRERREGPG---------SEPDSQVDG---GLSGASLGE-- 1412
Query: 1375 QRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWP 1434
K+L+KRSFSSQRP ++RQ+R+ PGG G GGG P R + +
Sbjct: 1413 --KKELAKRSFSSQRPVVDRQSRKLEPGG-FGEKPVRPGGGDTSP-------RYESQQNG 1462
Query: 1435 SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPG 1494
+P R P+E PG S + + L++ H++ A + +A ++ + ++ + AP
Sbjct: 1463 TPLKVKRSPDEALPGGLSGCSSGSGHSPYALERAAHAS-ADLPEASSKKAEKEAKLAAPR 1521
Query: 1495 GHPRHKPGLPQAPQGPSPRP-PTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGV 1553
QG + + Y + + SS E G MV G
Sbjct: 1522 A----------GEQGEAMKQFDLNYGSAIIENCGSSPGEESEVGSMV---------GEGF 1562
Query: 1554 SPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSK--PEGPGPQ----AESRDTGT--EA 1605
K++ R + +E+++ P L S+ P Q E D +
Sbjct: 1563 IEVLTKKQRRLLEEERRKKEQAVQVPVKGRGLSSRIPPRFAKKQNNLCLEQGDVTVPGSS 1622
Query: 1606 LTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDV------AGTEMSQSDSGVDLSGDS 1659
L IW +++ + + + W + ++ F G + SQ DSGVDLS +S
Sbjct: 1623 LGTEIW---ESSSQALPVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAES 1679
Query: 1660 QVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDR 1719
+ SS SQRSSP G LK P+ G E S + P P+
Sbjct: 1680 RESSATSSQRSSPYGTLK------PEEMSGPG-----LAEPKADSHKEQAPKPSEQKDSE 1728
Query: 1720 KELPREQPLPPGPIGTERSQRTDRGTE-----PGPIRP----------SHRPGPPVQFGT 1764
+ + + PGPIG ERS + +G+E G + P S P PP++FG
Sbjct: 1729 QGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVDSVLPVPPIEFGV 1788
Query: 1765 SDKDSDLRLVVGDS--------LKAEKEL--TASVTEAIPV-SRDWEL----------LP 1803
S KDSD L G + +K + L A +T++IP+ RD + P
Sbjct: 1789 SPKDSDFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILRRDHHIQRAIGLSPMSFP 1848
Query: 1804 SAAASAEPQS--KNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNS 1861
+A + + +S K ++ +PE SS G G PSS S G S
Sbjct: 1849 TADLTLKMESARKAWENSPSLPEQSSPG-----GAGSGIQPPSSVGASSGVNYSSF---- 1899
Query: 1862 GGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVL 1921
G S+ P +P PSA + G L +LD G V
Sbjct: 1900 -----GGVSMPP-------MPVASVAPSASMPGSHLPPLYLD--------------GHV- 1932
Query: 1922 YPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLL 1981
F P P +P Q T LQ Q G L G P Q
Sbjct: 1933 -----FASQPRLVPQTIPQQQSYQQAAAAQQIPISLHTSLQAQAQLG-LRGGLPVSQ--- 1983
Query: 1982 PMVDSQLPVVNFGSLPP-------APPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVL 2034
SQ F SL P P +PP +L G AL+PP A P P V
Sbjct: 1984 ----SQ---EIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAF-PGMQPLEMVK 2035
Query: 2035 PSPARPFPASLGRAEL 2050
P P+ G L
Sbjct: 2036 PQSGSPYQPMSGNQAL 2051
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 503 bits (1294), Expect = e-141
Identities = 524/1702 (30%), Positives = 685/1702 (40%), Gaps = 361/1702 (21%)
Query: 1 MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA 60
MS++SG + K KDGKKY++L+LF+TYKGKSLE QK RHGLQSLGKV I+RRMPPPA
Sbjct: 1 MSEKSGQSTKAKDGKKYATLSLFNTYKGKSLETQKTTA--RHGLQSLGKVGISRRMPPPA 58
Query: 61 NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN 120
NLPSLKAENKGNDPNV++VPKDGTGWASKQEQ + + T + P +QP P P
Sbjct: 59 NLPSLKAENKGNDPNVNIVPKDGTGWASKQEQHE----EEKTPEVPPAQPKPGVAAP--- 111
Query: 121 QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD 180
P V KSWA S G GDG + +S ++EFP+LQAAGDQ+
Sbjct: 112 ------------PEVAPAPKSWA--SNKQGGQGDGIQVNSQF----QQEFPSLQAAGDQE 153
Query: 181 KAAKERESAEQSSGPGPSLRPQNSTTWRDGG-GRGPDELEGPDSKLHHGHDPRGGLQPS- 238
K KE+E+ + + GPGPSLRP N WRDGG G D KL + G
Sbjct: 154 K--KEKETNDDNYGPGPSLRPPNVACWRDGGKAAGSPSSSDQDEKLPGQDESTAGTSEQN 211
Query: 239 ------------GPPQFP----------PYRGMMPPFMYPPY--LPFPPPYGPQGPYRYP 274
GPPQ YR MMPP+M+ Y + +PP +GP R+P
Sbjct: 212 DILKVVEKRIACGPPQAKLNGQQAALASQYRAMMPPYMFQQYPRMTYPPLHGPM---RFP 268
Query: 275 TPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKE---FDQLDQENDDGWAGAHE 331
PS G RG GPP RPSIL LKE FD LD E D+GWAGA
Sbjct: 269 ----PSLSETNKGLRGRGPPPSWASEPERPSILSASELKELDKFDNLDAEADEGWAGAQM 324
Query: 332 EVDYTEKLKFSDE-EDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE-PPTPK 389
EVDYTE+L FSD+ E G +S +E + S+++ E E D +S+ P P
Sbjct: 325 EVDYTEQLNFSDDDEQGSNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPS 384
Query: 390 TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDY--PDRGGPPCKPPAPEDEDE 447
A + P LPPP + A PP P R GP DEDE
Sbjct: 385 VAKVPYGKGPSFNQ-ERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDE 443
Query: 448 AWRQRRKQSSSEISLAVERA---------------------------------------- 467
W+QRR+Q S EIS AVERA
Sbjct: 444 IWKQRRRQQS-EISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502
Query: 468 ----RRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPA 523
R R +E ER + E+ + +R ++ +K + E
Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE 562
Query: 524 VPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGS 583
KEL E E E + + P L S +S +
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKE-REKLEEKIEPREPNLEPMVEKQESENSCN 621
Query: 584 FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSL 643
E PV + S + TP V + EP+ G +P + ++QKSL
Sbjct: 622 KEEEPVFTRQDSNRSEKE-------ATPVVHETEPES---GSQPRPAVLSGYFKQFQKSL 671
Query: 644 PPRFQR-----------QQQEQ-----------------------LLKQQQQHQWQQHQQ 669
PPRFQR QQQ+Q L + Q H
Sbjct: 672 PPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLYQPMQPHPQHLASM 731
Query: 670 GSAPPTPVPPSPPQPVTLGAVPAPQAPPP-----PPKALYPGALGRPPPMPPMNFDPRWM 724
G P + S P + PA PP PPK L P +F+
Sbjct: 732 GFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIAR 791
Query: 725 MIPPYV----DPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
+ +PR+L G P P + E D ++ ++ A E
Sbjct: 792 SARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEH 851
Query: 781 GTPPVDPKL--------AWVGDVFTATPAEPRPL-TSPLRQAADEDDKGMRSETPPVPPP 831
PK A V + + + RP T Q+A + ++ + P
Sbjct: 852 NQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHTDANNQSACFEAPDQKTLSAPQEER 911
Query: 832 PPYLASYPGF--------------------PENGAPGPPISRFPLEEPGPRPLPWPPGSD 871
+ S P P G P +EP RP P
Sbjct: 912 ISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEG 971
Query: 872 EVAKIQTPPPKKE-PPKEETAQLTGPEAGRKPA---RGVGSGGQGPPPPRRESRTETRWG 927
+ + P P+K K ET P + R+ R V G P R+ + E
Sbjct: 972 FIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQR 1031
Query: 928 ------------------PRPGSSRRGIPPEEPGAPPRRAGPIKKPPP---------PTK 960
P + PP P PP P PPP T+
Sbjct: 1032 KEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTE 1091
Query: 961 VEELPPKPLEQGDETPKPP------KPDPLKITKGKLGGP---KETPPNGNLS------- 1004
L KP Q E P P +P + + + P +E P +S
Sbjct: 1092 TATLAQKP-SQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIER 1150
Query: 1005 PAPRLRRDYSYERVGPTSC----------------RGRGRGEYFARGRGFRGTYGGRGRG 1048
P P R E P RGRGRGEY++RGR +RG+YGGRGRG
Sbjct: 1151 PRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRG 1210
Query: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAP-RGRTASETRSEGSEYEEIPKRRRQRGSE 1107
R R Y ++R + R + P P R R SETRSE S++E +PKRRRQRGSE
Sbjct: 1211 GRGHT-RDYPQYRDNKPR-----AEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSE 1264
Query: 1108 --TGSETHESDLAPSDKEA------PTPKEGTLTQVPLAPPPPGAPPSPAP--------- 1150
T SE HES SDK++ P +E + P+ P P +
Sbjct: 1265 TDTDSEIHES---ASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRIDNRLLEKP 1321
Query: 1151 -ARFTARGGRVFTPRGVPSRRGRG----------GGRP--------PPQVCPGWSPPAKS 1191
R + F P+G P+RRGRG GGRP P W+ P +S
Sbjct: 1322 YVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWN-PRQS 1380
Query: 1192 LAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDG-ERPRRRRHGRAQQ 1250
PK P PP + E+ I P+A + ERPRR+R R +
Sbjct: 1381 EVPK--PEDGEPPRRH---EQFI-----PIAADKRPPKFERKFDPARERPRRQRPTRPPR 1430
Query: 1251 QDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLS 1310
QDKPPRFRRL+ ERE A++ +E + G + V + K+PDLS
Sbjct: 1431 QDKPPRFRRLR-EREAASKSNE-----VVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLS 1484
Query: 1311 NQN-SDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMS 1369
NQN SDQANEEWETASESSDF R D++ L + V G
Sbjct: 1485 NQNSSDQANEEWETASESSDFNERRERDEKKNAD--LNAQTVVKVG-------------- 1528
Query: 1370 RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSG-SSSGGGGGGPGGRTGPGRG 1428
++ ++++KRSFSSQRP ++RQNRR G++G SG GP R
Sbjct: 1529 -ENVLPPKREIAKRSFSSQRP-VDRQNRR-------GNNGPPKSGRNFSGP-------RN 1572
Query: 1429 DKRSWPSPKNRSRPP-EERPPG 1449
++RS P K+ R P +++P G
Sbjct: 1573 ERRSGPPSKSGKRGPFDDQPAG 1594
Score = 72.8 bits (177), Expect = 3e-12
Identities = 82/268 (30%), Positives = 117/268 (43%), Gaps = 47/268 (17%)
Query: 1870 SLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLY-----PP 1924
SL PYRSQP ++ + PS +LSG A+ +F T+Q EL K +G P
Sbjct: 2463 SLQPYRSQPAFMQSSLSQPSVVLSGTAIH----NFPTVQHQELAKAQSGLAFQQTSNTQP 2518
Query: 1925 PSFLY------SPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGF---LPSGAP 1975
LY + S L DT LLQ R +L S+ YS +Q GQ+ F S +
Sbjct: 2519 IPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTAQSPSA 2578
Query: 1976 AQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLP 2035
QQ+ +P+ SQL + NFGS PL LP LQPP P + P
Sbjct: 2579 LQQVTVPLPASQLSLPNFGS-------TGQPLIALP--QTLQPPLQHTTPQAQAQSLSRP 2629
Query: 2036 SP-ARPF----PASLGRA------ELHPVELKPFQDYQKLSSNLGGPGSSRTPP-TGRSF 2083
+ ++PF PA + ++ +ELK F + PG TPP GRS
Sbjct: 2630 AQVSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIK-----PG---TPPIAGRST 2681
Query: 2084 SGLNSRLKATPSTYSGVFRTQRVDLYQQ 2111
+ +S +AT ++ + +YQ+
Sbjct: 2682 TPTSSPFRATSTSPNSQSSKMNSIVYQK 2709
Score = 58.5 bits (140), Expect = 7e-08
Identities = 140/649 (21%), Positives = 204/649 (31%), Gaps = 112/649 (17%)
Query: 194 GPGPSLRPQNSTTWRDGGGR----GPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRG- 248
G P RP +T R R P + E P P G P QF P
Sbjct: 1352 GRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPK--------PEDGEPPRRHEQFIPIAAD 1403
Query: 249 MMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLV---------- 298
PP + P Q P R P D P RF R+ + +V
Sbjct: 1404 KRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNN 1463
Query: 299 ---EPV---GRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDE 352
EPV G S K +L + DQ N++ W A E D+ E+ + DE+ D +
Sbjct: 1464 VAQEPVNTLGDISGNKTPDLSNQNSSDQANEE-WETASESSDFNERRE-RDEKKNADLNA 1521
Query: 353 EGA---------EGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEP 403
+ ++ + +RP + ++GN+ PK+ + E
Sbjct: 1522 QTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNG-----PPKSGRNFSGPRNERRS 1576
Query: 404 GPPAPKPPLPPPHRGPAGNWG---------------PPGDYPD---------RGGPPCKP 439
GPP+ P PAG G P G R P P
Sbjct: 1577 GPPSKSGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGP 1636
Query: 440 PAPEDEDEAWRQRRKQSSSEI-------------------------SLAVERARRRREEE 474
P+++ +A Q + + + + ++ ++R ++E
Sbjct: 1637 KKPKEKVDALSQFDLNNYASVVIIDDHPEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDE 1696
Query: 475 ERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAP 534
ERR +EE+ K K +EK + +L A A A A L + P P
Sbjct: 1697 ERRKKEEQVIQVWNK-KNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLP 1755
Query: 535 PPASAPTPETEPEEPAQAP-PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQL 593
P SA P + AP PA TP P +AP S +++S ASP+ P
Sbjct: 1756 PSTSASVPAS-----TSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVS 1810
Query: 594 PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQE 653
S P +T P P + P L
Sbjct: 1811 ASAS----VSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILAS 1866
Query: 654 QLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPP 713
L +AP P P T AP + P A P + P P
Sbjct: 1867 ALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPA--PTPVSAPNP 1924
Query: 714 MPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
PP + P +P LQ PP PS +P ++ +G
Sbjct: 1925 APPAPAQTQAQTHKPVQNP--LQTTSQSSKQPP---PSIRLPSAQTPNG 1968
Score = 57.8 bits (138), Expect = 1e-07
Identities = 90/351 (25%), Positives = 116/351 (33%), Gaps = 90/351 (25%)
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT-----PVPPSPPQPVTLGAVPAPQAPP 697
LPPRF ++Q + + Q PP+ P S P P TL VPA + P
Sbjct: 1725 LPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP 1784
Query: 698 PPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRE 757
P L P P+P PL S VP
Sbjct: 1785 VPASTLAPVLASTSAPVP----------------------ASPLAPVSASASVSASVPAS 1822
Query: 758 RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS---PLRQAA 814
S + +SS APA P P LA V +TPA L S P+ +A
Sbjct: 1823 TSAAAITSSS-----APA-----SAPAPTPILASV-----STPASVTILASASIPILASA 1867
Query: 815 DEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR-------FPLEEPGPRPLPWP 867
+ S + P P P AS P P AP P S P P P P P
Sbjct: 1868 ------LASTSAPTPAP---AASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP 1918
Query: 868 PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWG 927
+ P P P + AQ P + P + + PPP R +T G
Sbjct: 1919 --------VSAPNPAPPAPAQTQAQTHKPV--QNPLQTTSQSSKQPPPSIRLPSAQTPNG 1968
Query: 928 PRPGSSRRGI-PPEEPG-----------APP-------RRAGPIKKPPPPT 959
+S + I P+ G APP ++ GPI P PP+
Sbjct: 1969 TDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPS 2019
Score = 51.2 bits (121), Expect = 1e-05
Identities = 244/1293 (18%), Positives = 412/1293 (31%), Gaps = 250/1293 (19%)
Query: 589 VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQ 648
V+P+ K+ PP PPP PP P ++P+ + P QP ++ +P + + +
Sbjct: 1048 VKPEKTEKKDLPPP---PPPPQPPAP-IQPQS--VPPPIQPEAEK--FPSTETATLAQKP 1099
Query: 649 RQQQEQLLKQQQQHQWQQ-----HQQGSAPPTPVPPSPPQPVTLGAV----PAPQAPPPP 699
Q E+ L+ Q + +QQ A P P+ V + P P + P
Sbjct: 1100 SQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRP-- 1157
Query: 700 PKALYPGALGRPPPMPPMNF-----DPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV 754
A+ + +PP + + W Y +GR ++Y G G
Sbjct: 1158 -------AVKKESTLPPRTYWKEARERDWFPDQGY------RGRGRGEYYSRGRSYRGSY 1204
Query: 755 P-RERSDSGGS-------SSEPFDRHAPA-MLRERGTPPVDPKLAWVGDVFTATPAEPRP 805
R R G + ++P H P+ LR+R + F P R
Sbjct: 1205 GGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSE----SSDFEVVPKRRRQ 1260
Query: 806 ------LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEP 859
S + ++A + D + + P P EN P P S F +
Sbjct: 1261 RGSETDTDSEIHESASDKDSLSKGKLPKREERP----------ENKKPVKPHSSFKPDNH 1310
Query: 860 ---GPRPLPWPPGSDEVAKIQTPPPKKEPPKEE---TAQLTGPEAGRKPARGVGSGGQGP 913
R L P D+ PK EP + T + G + G +P+R P
Sbjct: 1311 VRIDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSR--------P 1362
Query: 914 PPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPK------ 967
RR + + +W PR +P E G PPRR P ++ PPK
Sbjct: 1363 STLRRPAYRDNQWNPRQSE----VPKPEDGEPPRRHEQFI----PIAADKRPPKFERKFD 1414
Query: 968 PLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRG 1027
P + +P +P P++ P PR RR E ++
Sbjct: 1415 PARERPRRQRPTRP------------PRQDKP-------PRFRRLREREAASKSN----- 1450
Query: 1028 RGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASET 1087
G + + GD N + + ET
Sbjct: 1451 ------------EVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWET 1498
Query: 1088 RSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS 1147
SE S++ E RR+R + ++ + + + PK
Sbjct: 1499 ASESSDFNE----RRERDEKKNADLNAQTVVKVGENVLPPK------------------- 1535
Query: 1148 PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKE 1207
R A+ R F+ + R+ R G PP+ +S P PPSK
Sbjct: 1536 ----REIAK--RSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSG-------PPSKS 1582
Query: 1208 PLKEKLIPGPLSPVARGGSNGGS---NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264
+ P NG S G+ +G + + ++++ P + +E+
Sbjct: 1583 GKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEK 1642
Query: 1265 ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR---------RAAAKSPDLSNQNSD 1315
+A + ++ PE VTV P+ +K Q+ +
Sbjct: 1643 VDALSQFDLNNYASVVIIDDHPE-----VTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEE 1697
Query: 1316 QANEEWETASESSDFTSERRGDKEAP--PPVLLTPKAVGTPGGGGGGAVPGI-SAMSRGD 1372
+ +E + + + +G + PP +A G +VP + SA
Sbjct: 1698 RRKKEEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPS 1757
Query: 1373 LSQRAKDLSKRSFSSQRPGMERQNRRPGPGGK-AGSSGSSSGGGGGGPGGRTGPGRGDKR 1431
S + + + P P A S+S P
Sbjct: 1758 TSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSA 1817
Query: 1432 SWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGI----QQALAQLSSRQ 1487
S P+ + + P P P P ++V S PA + ++ L+S
Sbjct: 1818 SVPASTSAAAITSSSAPA-SAPAPTPILASV--------STPASVTILASASIPILASAL 1868
Query: 1488 GSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTP 1547
S +AP AP SP P P S ++ TP
Sbjct: 1869 ASTSAP----------TPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTP 1918
Query: 1548 RDSAGVSPFPPKRRERPPRKP------ELLQEESLPPPHSSGFLGSKPEGPGPQAESRDT 1601
+ +P P + + KP Q PPP P G A +
Sbjct: 1919 VSAPNPAPPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSI 1978
Query: 1602 GTE----ALTPHIWNR-------LHTATSR----KSYRPSSMEPWMEPLSPFEDVAGTEM 1646
T LT +W+ L+ + + +P S+ W +PL+ F +E
Sbjct: 1979 QTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEG 2038
Query: 1647 SQS--DSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGS 1704
+++ +SG+++ D+ P S + + + + K P P GP +
Sbjct: 2039 AKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKA 2098
Query: 1705 EPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGP-PVQFG 1763
+ + P +P + + PGPIG ERS + + + + P + P P
Sbjct: 2099 Q--KLPDLSPVENKEHK--------PGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVR 2148
Query: 1764 TSDKDSDLRLVVGDSLKAEKELTASVTEAIPVS 1796
++D V KA E++ + I VS
Sbjct: 2149 STDP------VTTKETKAVSEMSTEIGTMISVS 2175
Score = 49.7 bits (117), Expect = 3e-05
Identities = 218/1049 (20%), Positives = 327/1049 (31%), Gaps = 188/1049 (17%)
Query: 1188 PAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGR 1247
P K+ PP P P P++ + +P P+ P A + + + + +
Sbjct: 1050 PEKTEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEP 1109
Query: 1248 AQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSP 1307
P + + Q+ A E K PE+ ++ V PR + P
Sbjct: 1110 VSTVQVEPAVKTVNQQTMAAPVVKEEKQ----------PEKVISKDLVIERPRPDSR--P 1157
Query: 1308 DLSNQNSDQANEEWETASESSDFTSER---RGDKEAPPPVLLTPKAVGTPGGGGGGAV-- 1362
+ +++ W+ A E F + RG E + G G GG G
Sbjct: 1158 AVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRD 1217
Query: 1363 --------PGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGG 1414
P + G L QR ++ RS SS + ++ R+ G S S
Sbjct: 1218 YPQYRDNKPRAEHIPSGPLRQR-EESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS 1276
Query: 1415 GGGGPGGRTGPGRGDKRSWPSPK--NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVI--- 1469
DK S K R PE + P P P + R+D +
Sbjct: 1277 --------------DKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHV--RIDNRLLEK 1320
Query: 1470 -------HSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPR--------- 1513
+ P + + R G+ G P +P P + P+ R
Sbjct: 1321 PYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQS 1380
Query: 1514 ---------PPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERP 1564
PP R+E + P FE R PR P P R+++P
Sbjct: 1381 EVPKPEDGEPPRRHEQFIPIAADKRPPKFERKFDPARE---RPRRQR---PTRPPRQDKP 1434
Query: 1565 PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYR 1624
PR L + E+ S+ + G T I S ++
Sbjct: 1435 PRFRRLREREAASK--SNEVVAVPTNGTVNNVAQEPVNTLG---DISGNKTPDLSNQNSS 1489
Query: 1625 PSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGP--------------CSQRS 1670
+ E W E S D DL+ + V G SQR
Sbjct: 1490 DQANEEW-ETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRP 1548
Query: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP---PPAPHDG----DRKELP 1723
+G GPPK S GPP R P PA G +
Sbjct: 1549 VDRQNRRGN-NGPPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAH 1607
Query: 1724 REQPLPPGPIGTERSQRTDRGTE---PGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLK 1780
++ +P G T + E PGP +P + QF ++ S + ++ D
Sbjct: 1608 HQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVV--IIDDH-- 1663
Query: 1781 AEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGS 1840
P +PQS D G +RL E
Sbjct: 1664 ----------------------PEVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKK 1701
Query: 1841 A-------GPSSSQISGGAMDSQLHPNSGGFRP-GTPSLHPYRSQPLYLPPGPAPPSALL 1892
++ G + S+L P + G S P L P PPS
Sbjct: 1702 EEQVIQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPP-LASAPLPPSTSA 1760
Query: 1893 SGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSP--AFCPSPLPDTSLLQVRQDL 1950
S A + + AT L +PA P P+ +P A +P+P + L V
Sbjct: 1761 SVPASTS-----APLPAT-LTPVPAS-TSAPVPASTLAPVLASTSAPVPASPLAPVSASA 1813
Query: 1951 PSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDS--QLPVVNFGSLP---------PA 1999
+ ++ S P+ APA +L V + + ++ S+P A
Sbjct: 1814 SVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSA 1873
Query: 2000 PPPAPP------PLSLLPVGPALQP-------PSLAVRPPPAPATRVLPSPARPFPASLG 2046
P PAP P+ P PA P P+ A P PAP P+PA P PA
Sbjct: 1874 PTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQT- 1932
Query: 2047 RAELHPVELKPFQDYQKLSSNLGGPGSSRTP----PTGRSFSGLNSRLKATPSTYSGVFR 2102
+A+ H P Q + S P S R P P G + ++ TP ++ G
Sbjct: 1933 QAQTHKPVQNPLQTTSQSSKQ--PPPSIRLPSAQTPNGTDYVASGKSIQ-TPQSH-GTLT 1988
Query: 2103 TQRVDLYQQASPPDALRWIPKPWERTGPP 2131
+ D + +PP L I K PP
Sbjct: 1989 AELWD--NKVAPPAVLNDISKKLGPISPP 2015
Score = 44.7 bits (104), Expect = 0.001
Identities = 142/620 (22%), Positives = 205/620 (33%), Gaps = 110/620 (17%)
Query: 73 DPNVSLVPKDGTGWASKQ-EQSDPKSSDASTAQPPESQPL--PASQTPASNQPKRPPAA- 128
+P S VPK G ++ EQ P ++D +PP+ + PA + P +P RPP
Sbjct: 1376 NPRQSEVPKPEDGEPPRRHEQFIPIAADK---RPPKFERKFDPARERPRRQRPTRPPRQD 1432
Query: 129 --PENTPLVPSGVKSWAQASVTHGAHGDGGRAS----SLLSRFSREEFPTLQAAGDQDKA 182
P L S + V +G + + L S + P L D+A
Sbjct: 1433 KPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQA 1492
Query: 183 AKERESAEQSSGPGPS-----------------------LRPQNSTTWRDGGGRGPDELE 219
+E E+A +SS L P+ R + P + +
Sbjct: 1493 NEEWETASESSDFNERRERDEKKNADLNAQTVVKVGENVLPPKREIAKRSFSSQRPVDRQ 1552
Query: 220 GPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGP 279
++ + P+ G SGP R PP PF P G +G
Sbjct: 1553 ---NRRGNNGPPKSGRNFSGPRN---ERRSGPPSKSGKRGPFDDQ--PAGTTGVDLINGS 1604
Query: 280 SRFPRVAGPRGSGPP-------MRLVEPVGRPSILKE--DNLKEFDQ--------LDQE- 321
S + P G+G + +P P KE D L +FD +D
Sbjct: 1605 SAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHP 1664
Query: 322 ------------NDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEER 369
NDDG+ E V ++ + DEE + ++ ++ + + G +
Sbjct: 1665 EVTVIEDPQSNLNDDGFT---EVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQ 1721
Query: 370 ----PP-----EADG-KKGNSPNSEPP---TPKTAWAETSRPPETEPGPPAPKPPLPPPH 416
PP +A G ++ S S PP P S P T PA P+P
Sbjct: 1722 TSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPAST 1781
Query: 417 RGPAGNWGPPGDYPDRGGP-PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEE 475
P P P P AP + S+S ++ A
Sbjct: 1782 SAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPT 1841
Query: 476 RRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP--STPAPP----PAVPKELP 529
+ A L A A +AP AP S+PA P P +P P
Sbjct: 1842 PILASVSTPASVTILASASIPILAS---ALASTSAPTPAPAASSPAAPVITAPTIPASAP 1898
Query: 530 ---APPAPPPASAPTPETEP-EEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFE 585
P AP ASAP P P P APPA P A V T+S SS +
Sbjct: 1899 TASVPLAPASASAPAPAPTPVSAPNPAPPA---PAQTQAQTHKPVQNPLQTTSQSS---K 1952
Query: 586 ASPVEPQLPSKEGPEPPEEV 605
P +LPS + P + V
Sbjct: 1953 QPPPSIRLPSAQTPNGTDYV 1972
Score = 39.3 bits (90), Expect = 0.042
Identities = 38/135 (28%), Positives = 54/135 (40%), Gaps = 7/135 (5%)
Query: 499 APDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQST 558
AP A A+ P AP++ + P P + AP PPA A T + + +P Q P Q+T
Sbjct: 1890 APTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQT-QAQTHKPVQ-NPLQTT 1947
Query: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPP--VPKV 616
P++ T + + + AS Q P G E PP + +
Sbjct: 1948 SQSSKQPPPSIRLPSAQTPNGT--DYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDI 2005
Query: 617 EPKGDGIGPTRQPPS 631
K I P QPPS
Sbjct: 2006 SKKLGPISPP-QPPS 2019
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 155 bits (393), Expect = 3e-37
Identities = 323/1242 (26%), Positives = 412/1242 (33%), Gaps = 217/1242 (17%)
Query: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKSLPP 645
+P P P+ +GP+ P+ P P P +P G QP S G G P +S P
Sbjct: 94 APTRP--PNGQGPQGPKGDPGPPGIPGRNGDP-----GIPGQPGSPGSPGPPGICESCPT 146
Query: 646 ---RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPP----QPVTLGAVPAPQAPPP 698
+ Q +K G A P P PP PP P + G+ P Q PP
Sbjct: 147 GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGP-PGPPGPPGTSGHPGSPGS-PGYQGPPG 204
Query: 699 PPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFY-----PPGVH-PSG 752
P P PP PP P P D GRP PPG+ P+G
Sbjct: 205 EPGQAGPSG----PPGPPGAIGPSG---PAGKDGE--SGRPGRPGERGLPGPPGIKGPAG 255
Query: 753 L--VPRERSDSG--GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
+ P + G G + E + AP + E G P + +G P E
Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP--RGAPGERGRPGL 313
Query: 809 PLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWP 867
P A +D S+ P PP PP A +PG P G GP S PG R P P
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373
Query: 868 PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWG 927
G PP P + GP AG A G+ G +GPP P
Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEM--GP-AGIPGAPGL-MGARGPPGP----------- 418
Query: 928 PRPGSSRRGIPPEEPGA-PPRRAGPIKKPPPPTKVEE--LPPKPLEQG----DETPKPPK 980
+ G P GA P + G +P P + E +P P +G D +P P
Sbjct: 419 ----AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474
Query: 981 PDPLKITKGKLGGP---KETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRG 1037
+ L G+ G P PNG + GP G + G G
Sbjct: 475 ANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534
Query: 1038 FRGTYGGRGRGARSREFRSYREFRGDDGRGG--GTGGPNHP------PAPRGRTASETRS 1089
RG G G G S +G+ GR G G GP P P+G + ++
Sbjct: 535 MRGMPGSPG-GPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 1090 --EGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGT--LTQVPLAPPPP--- 1142
G P+ + ETG + P + T G L +P PP
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653
Query: 1143 GAPPSPAPARFT----ARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAK-----SLA 1193
G P P P A GG+ G P RG G P + G PP +
Sbjct: 654 GKPGEPGPKGDAGAPGAPGGK--GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG 711
Query: 1194 PKKPPTGPLPPSKEPLKEKL----IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
P PP P + + + PGP G G V +DG R G
Sbjct: 712 PPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG--- 768
Query: 1250 QQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDL 1309
PP Q + G+ G P + P +PG T P P A P
Sbjct: 769 ----PP--GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE----TGPPGP----AGFPGA 814
Query: 1310 SNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMS 1369
QN + + A G+K P P G PGG G PG +
Sbjct: 815 PGQNGEPGGKGERGAP----------GEKGEGGP----PGVAGPPGGSGPAGPPGPQGVK 860
Query: 1370 RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PG-- 1426
S + + PG N PGP G +GS G G GP G TG PG
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD---GPPGPAGNTGAPGSP 917
Query: 1427 --RGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLS 1484
G K P + P + PPG P P GI A ++
Sbjct: 918 GVSGPKGDAGQPGEKGSPGAQGPPGAP--------------------GPLGI----AGIT 953
Query: 1485 SRQGSVTAPG-GHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSD--PHFEEPGPMVR 1541
+G PG PR PG PQ +G S +P +GLS + P + P +
Sbjct: 954 GARGLAGPPGMPGPRGSPG-PQGVKGESGKPGA--------NGLSGERGPPGPQGLPGLA 1004
Query: 1542 GVGGTP-RDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGP-GPQAESR 1599
G G P RD S P R P K + + S P + G G P GP GP +S
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPG--PPGPVGPAGKSG 1062
Query: 1600 DTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDS 1659
D G P P AG G
Sbjct: 1063 DRGESG----------------------------PAGP----AGAPGPAGSRGAPGPQGP 1090
Query: 1660 QVSSGPCSQRSSPDGGLKG--AAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDG 1717
+ G +R + G+KG G P PG P G PG P R P P
Sbjct: 1091 RGDKGETGERGA--AGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP-RGPVGPSGP 1147
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPP 1759
K+ P P GP G R R +RG+E P P +PGPP
Sbjct: 1148 PGKDGTSGHPGPIGPPG-PRGNRGERGSEGSPGHPG-QPGPP 1187
Score = 143 bits (360), Expect = 2e-33
Identities = 321/1301 (24%), Positives = 396/1301 (30%), Gaps = 292/1301 (22%)
Query: 374 DGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRG 433
D ++ + PN E P + A +PP PP + P +GP G+ GPPG P R
Sbjct: 68 DDQELDCPNPEIPFGECC-AVCPQPPTAPTRPPNGQGP-----QGPKGDPGPPG-IPGRN 120
Query: 434 GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRL 493
G P P P +S + +
Sbjct: 121 GDPGIPGQPGSPGSPGPPGICESCPT----------------------GPQNYSPQYDSY 158
Query: 494 DEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAP 553
D K G L P PA P P PP P P P P P EP QA
Sbjct: 159 DVKSGVAVGGLAGYPG--PAGPPGPPGPPGTSGH-PGSPGSPGYQGP-----PGEPGQAG 210
Query: 554 PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG-PEPPEEVPPPTTPP 612
P+ P P A P+ +G S P P + G P PP P P
Sbjct: 211 PS-GPPGPPGAIGPSGPAGKDGESG-----------RPGRPGERGLPGPPGIKGPAGIPG 258
Query: 613 VP--------------KVEPKGDGI-GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLK 657
P K E G+ G P G P + P R
Sbjct: 259 FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318
Query: 658 QQQQHQWQQHQQGSAPPTP-----VPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGR-- 710
+ + PP P P SP +G +P + P + PG G
Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378
Query: 711 ---PPPMPPMNFDP--RWMMIPPYVD--PRLLQGRPP-----LDFYP--------PGVHP 750
PP P +N P + M P + P L+ R P + P PG +
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438
Query: 751 SGLVPRERSDSG-----------------GSSSEPFDRHAPAMLRERGTP----PVDP-- 787
+ P R + G GS EP P ERG P P P
Sbjct: 439 AKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498
Query: 788 ---KLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-- 842
+ G+ PA PR + GMR P P P PG P
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG--MPGSPGGPGSDGKPGPPGS 556
Query: 843 --ENGAPGPPISRFPLEEPGPRPLPWPPGSD-------EVAKIQTPPPKKEPPKEETAQL 893
E+G PGPP P +PG P P G+D E P P+ P K
Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616
Query: 894 TGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--------PEEP--- 942
GP P G G GPP P+ GP + + G P P P
Sbjct: 617 QGPPGPTGP--GGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674
Query: 943 ---GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPP 999
GAP R P P + PP P E G PP P T G G P E
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGP-EGGKGAAGPPGPPGAAGTPGLQGMPGER-- 731
Query: 1000 NGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYRE 1059
G SP P+ + E GP + G+ RG G G G +
Sbjct: 732 GGLGSPGPKGDKG---EPGGPGADGVPGKD----GPRGPTGPIGPPGPAGQP-------- 776
Query: 1060 FRGDDGRGG-----GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHE 1114
GD G GG G GP P RG T + P Q G G
Sbjct: 777 --GDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA------GFPGAPGQNGEPGGKGERG 828
Query: 1115 SDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG 1174
AP +K P +A PP G+ P+ P P+GV RG G
Sbjct: 829 ---APGEKGEGGPP-------GVAGPPGGSGPAGPPG-----------PQGVKGERGSPG 867
Query: 1175 GR-----PPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGG 1229
G P + PG PP + P GP PS P K+ GP P G+ G
Sbjct: 868 GPGAAGFPGARGLPG--PPGSNGNP-----GPPGPSGSPGKD----GPPGPAGNTGAPGS 916
Query: 1230 SNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEA 1289
V G+ + G Q P L ARG G P + P +PGP+
Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ-- 974
Query: 1290 LTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPK 1349
+ E+ ++ S RG PP P
Sbjct: 975 ----------------------------GVKGESGKPGANGLSGERG----PPGPQGLPG 1002
Query: 1350 AVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSG 1409
GT G G PG + D S K + S PG PGP G AG SG
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062
Query: 1410 SSSGGGGGGPGGRTGPGRGDKRSWPSPK----------NRSRPPEERPPGLPLPPPPPSS 1459
G GP G PG R P P+ R + G P P P S
Sbjct: 1063 DRGESGPAGPAG--APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120
Query: 1460 SAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQG-------PSP 1512
PAG +QG++ +PG P P P G P P
Sbjct: 1121 -----------PGPAG----------QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGP 1159
Query: 1513 RPPTRYEPQRVNSGLSSDP-HFEEPGPMVRGVGGTPRDSAG 1552
P R G P H +PGP G G P G
Sbjct: 1160 IGPPGPRGNRGERGSEGSPGHPGQPGP--PGPPGAPGPCCG 1198
Score = 132 bits (332), Expect = 4e-30
Identities = 259/993 (26%), Positives = 326/993 (32%), Gaps = 206/993 (20%)
Query: 803 PRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGP 861
P+P T+P R + +G + + P PG P NG PG P +PG
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGP-----------PGIPGRNGDPGIP------GQPGS 131
Query: 862 RPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESR 921
P PPG E T P P + +G G +G GPP P S
Sbjct: 132 PGSPGPPGICE--SCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189
Query: 922 TETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKP 981
PGS PP EPG +AGP P PP + P P + E+ +P +P
Sbjct: 190 HPGS----PGSPGYQGPPGEPG----QAGPSGPPGPPGAIG--PSGPAGKDGESGRPGRP 239
Query: 982 DPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYE-------RVGPTSCRGRGR--GEYF 1032
+G G P P G + P ++ ++ G +G GE
Sbjct: 240 GE----RGLPGPPGIKGPAG-IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENG 294
Query: 1033 ARG-RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEG 1091
A G G RG G RGR + RG+DG G G P PP P G TA S G
Sbjct: 295 APGPMGPRGAPGERGRPGLPGAAGA----RGNDGARGSDGQPG-PPGPPG-TAGFPGSPG 348
Query: 1092 SEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPA 1151
++ E P + + S+ AP + P P+ Q P P PPG SP
Sbjct: 349 AKGEVGP-----------AGSPGSNGAPGQRGEPGPQGHAGAQGP--PGPPGINGSPG-- 393
Query: 1152 RFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKE 1211
G P G+P G G R PP PA + G P K K
Sbjct: 394 -----GKGEMGPAGIPGAPGLMGARGPPG-------PAGANGAPGLRGGAGEPGKNGAKG 441
Query: 1212 KLIPGPLSPVARGGSNGGSNVGMEDGE-----RPRRRRHGRAQQQDKPPRFRRLKQEREN 1266
+ PGP G G EDG+ P A + P FR
Sbjct: 442 E--PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFR-------- 491
Query: 1267 AARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASE 1326
G G P PA G PA R AA P
Sbjct: 492 GPAGPNGIPGEKGPAGERGAP--------GPAGPRGAAGEP------------------- 524
Query: 1327 SSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFS 1386
D G + P G+PGG G PG
Sbjct: 525 GRDGVPGGPGMRGMP----------GSPGGPGSDGKPG---------------------- 552
Query: 1387 SQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEE 1445
PG + ++ RPGP G +G G G GP G G PG+ +R P PP +
Sbjct: 553 --PPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610
Query: 1446 RPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQ--QALAQLSSRQGSVTAPGGH-PRHKPG 1502
P PP P+ + D + P G Q Q L G PG P+ G
Sbjct: 611 NGETGPQGPPGPTGPGGDKGD----TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666
Query: 1503 LPQAP--QGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVS----PF 1556
P AP +G + P R P GL+ P +RG G P G P
Sbjct: 667 APGAPGGKGDAGAPGERGPP-----GLAG-------APGLRGGAGPPGPEGGKGAAGPPG 714
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHT 1616
PP P + + L P G G +P GPG G T I
Sbjct: 715 PPGAAGTPGLQGMPGERGGLGSPGPKGDKG-EPGGPGADGVPGKDGPRGPTGPI------ 767
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGL 1676
+ +P P P +AG S + G G Q P G
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLP--GIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG-- 823
Query: 1677 KGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPP-PAPHDGDRKELPREQPLPPGPIGT 1735
KG P ++ G P A GPPG P PP P G+R P PG G
Sbjct: 824 KGERGAPGEKGEGGPPGVA----GPPGGSGPAGPPGPQGVKGERGS-----PGGPGAAGF 874
Query: 1736 ERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKD 1768
+ RG PGP + PGPP G+ KD
Sbjct: 875 PGA----RGL-PGPPGSNGNPGPPGPSGSPGKD 902
Score = 120 bits (301), Expect = 1e-26
Identities = 320/1274 (25%), Positives = 399/1274 (31%), Gaps = 290/1274 (22%)
Query: 211 GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPP-PYGPQG 269
G GP GP H P G GPP P G P P PP GP G
Sbjct: 174 GPAGPPGPPGPPGTSGHPGSP-GSPGYQGPPGEPGQAGPSGP-------PGPPGAIGPSG 225
Query: 270 PYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGA 329
P DG S P G RG P + P G P + FD + + G GA
Sbjct: 226 P---AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD--GRNGEKGETGA 280
Query: 330 HEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPK 389
LK + G E GA G + A GE P G G N
Sbjct: 281 -------PGLKGENGLPG----ENGAPGPMGPRGAPGERGRPGLPGAAGARGN------- 322
Query: 390 TAWAETSRPPETEPGPPAPKPPLP-PPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEA 448
+ +R + +PGPP P P G G GP G P G P + P + A
Sbjct: 323 ----DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS-PGSNGAPGQRGEPGPQGHA 377
Query: 449 WRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP 508
Q I+ G+P + + P
Sbjct: 378 GAQG-PPGPPGIN------------------------------------GSPGGKGEMGP 400
Query: 509 AAPPAAPSTPAP--PPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAA 566
A P AP PP AP A P EP PGV A
Sbjct: 401 AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGA 460
Query: 567 PTLVSGGGSTSSTSSGSFEAS-----------PVEPQ-LPSKEGPEPPEEVPPPTTPPVP 614
GS + + P P +P ++GP P P P
Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520
Query: 615 KVEPKGDGI--GP-TRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGS 671
EP DG+ GP R P G K PP Q + + Q G
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGF 580
Query: 672 APPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVD 731
P +P + G P PP K G G P P P + PP
Sbjct: 581 PGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG--DKGDTGPP--G 636
Query: 732 PRLLQGRPPLDFYPPGVHPSGLVPRERSDSG--GSSSEPFDRHAPAMLRERGTPPVDPKL 789
P+ LQG P PPG + P + D+G G+ D AP ERG P +
Sbjct: 637 PQGLQGLPGTGG-PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPG---ERGPPGLAGAP 692
Query: 790 AWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGP 849
G A P P E KG PP PP A PG G PG
Sbjct: 693 GLRGG---AGPPGP------------EGGKGAAG-----PPGPPGAAGTPGL--QGMPG- 729
Query: 850 PISRFPLEEPGPRP---LPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGV 906
R L PGP+ P PG+D V P K+ P+ GP
Sbjct: 730 --ERGGLGSPGPKGDKGEPGGPGADGV-------PGKDGPR-------GP---------- 763
Query: 907 GSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKK----PPPPTKVE 962
+G GPP P + PG G P PG R P ++ PP P
Sbjct: 764 -TGPIGPPGPAGQ----------PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG-- 810
Query: 963 ELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTS 1022
P P + G+ K + P + KG+ G P P G PA GP
Sbjct: 811 -FPGAPGQNGEPGGKGERGAPGE--KGEGGPPGVAGPPGGSGPA------------GPPG 855
Query: 1023 CRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGP--------N 1074
+G +G RG+ GG G F R G G G G P +
Sbjct: 856 PQGV---------KGERGSPGGPGAAG----FPGARGLPGPPGSNGNPGPPGPSGSPGKD 902
Query: 1075 HPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQ 1134
PP P G T + GS PK + E GS
Sbjct: 903 GPPGPAGNTGAP----GSPGVSGPKGDAGQPGEKGS------------------------ 934
Query: 1135 VPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWS--PPAKSL 1192
P A PPGAP A T G + P G+P RG P PQ G S P A L
Sbjct: 935 -PGAQGPPGAPGPLGIAGITGARG-LAGPPGMPGPRGS----PGPQGVKGESGKPGANGL 988
Query: 1193 APKKPPTGP--LP----PSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHG 1246
+ ++ P GP LP + EP ++ PG R GS GG G+R G
Sbjct: 989 SGERGPPGPQGLPGLAGTAGEPGRDGN-PGSDGLPGRDGSPGGK------GDRGENGSPG 1041
Query: 1247 RAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKS 1306
P + ++ RG G PA APGP + AP P+
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAG---PAGAPGPAGSRG----APGPQGPRGDK 1094
Query: 1307 PDLSNQNS----DQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAV----GTPGGGG 1358
+ + + + S + ++G +P P P+ G PG G
Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA--GPRGPVGPSGPPGKDG 1152
Query: 1359 GGAVPGISAMS--RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGG 1416
PG RG+ +R + S PG Q PGP G G+ G GG G
Sbjct: 1153 TSGHPGPIGPPGPRGNRGERGSEGS--------PGHPGQ---PGPPGPPGAPGPCCGGVG 1201
Query: 1417 ----GGPGGRTGPG 1426
G GG G
Sbjct: 1202 AAAIAGIGGEKAGG 1215
Score = 84.7 bits (208), Expect = 9e-16
Identities = 216/914 (23%), Positives = 268/914 (29%), Gaps = 213/914 (23%)
Query: 80 PKDGTGWASKQEQSDPKSSDASTAQP--PESQPLPASQTPASNQPKRPPAAPENTP--LV 135
P+ G A K D P P + LP + R PA P P
Sbjct: 445 PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKG 504
Query: 136 PSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQS--S 193
P+G + + GA G+ GR R + G K E
Sbjct: 505 PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPG 564
Query: 194 GPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGP-PQFPPYRGMMPP 252
PGPS G +G D G + + RGG P GP PQ PP +
Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGE-------RGG--PGGPGPQGPPGKN---- 611
Query: 253 FMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNL 312
GPQGP P P GP GP G L G P
Sbjct: 612 ----------GETGPQGP---PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG------- 651
Query: 313 KEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPE 372
E + + G AGA GA G + A GE PP
Sbjct: 652 -ENGKPGEPGPKGDAGA-----------------------PGAPGGKGDAGAPGERGPPG 687
Query: 373 ADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP--APKPPLP--PPHRGPAGNWGPPGD 428
G G + PP P E + PGPP A P L P RG G+ GP GD
Sbjct: 688 LAGAPGLRGGAGPPGP-----EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742
Query: 429 YPDRGGP----------------PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
+ GGP P PP P +
Sbjct: 743 KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ--------------------------- 775
Query: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPP 532
++ A L + G+P +R + P P P P + P
Sbjct: 776 ------PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG-------QNGEPG 822
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEAS---PV 589
AP + E P A P + G + GS + F + P
Sbjct: 823 GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG 882
Query: 590 EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQR 649
P GP P P PP P G T P S G+ PK P
Sbjct: 883 PPGSNGNPGPPGPSGSPGKDGPPGP--------AGNTGAPGSPGVSGPKGDAGQP----- 929
Query: 650 QQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALG 709
++GS P PP P P+ + + + PP PG G
Sbjct: 930 -----------------GEKGS-PGAQGPPGAPGPLGIAGITGARGLAGPPG--MPGPRG 969
Query: 710 RPPPM--------PPMNFDPRWMMIP-PYVDPRL--LQGRPPLDFYPPGVHPSGLVPRER 758
P P P N P P P L G P D P GL R+
Sbjct: 970 SPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS---DGLPGRDG 1026
Query: 759 SDSG-GSSSEPFDRHAPAMLRERGTP-PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADE 816
S G G E AP G P PV P GD + PA P P
Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGP-AGKSGDRGESGPAGPAGAPGPAGSRGAP 1085
Query: 817 DDKGMRSETPPV-PPPPPYLASYPGFPEN----GAPGPPISRFPLEEPGPRPLPWPPGSD 871
+G R + + + GFP N G+PGP + + PGP P G
Sbjct: 1086 GPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG-- 1143
Query: 872 EVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPG 931
P P K+ T+ GP GPP P R +R E PG
Sbjct: 1144 ---------PSGPPGKDGTSGHPGP--------------IGPPGP-RGNRGERGSEGSPG 1179
Query: 932 SSRRGIPPEEPGAP 945
+ PP PGAP
Sbjct: 1180 HPGQPGPPGPPGAP 1193
Score = 47.8 bits (112), Expect = 1e-04
Identities = 94/395 (23%), Positives = 120/395 (30%), Gaps = 79/395 (20%)
Query: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
P A P + N + P +G K P + + P S P +
Sbjct: 869 PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ 928
Query: 117 PA---SNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTL 173
P S + PP AP P G+ A G G G S P
Sbjct: 929 PGEKGSPGAQGPPGAPG-----PLGIAGITGARGLAGPPGMPGPRGS----------PGP 973
Query: 174 QAA-GDQDKAAKERESAEQSSGPGPSLRPQNSTTWRD---GGGRGPDELEGPDSKLHHGH 229
Q G+ K S E+ PGP P + T + G G D L G D G
Sbjct: 974 QGVKGESGKPGANGLSGERGP-PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS-PGGK 1031
Query: 230 DPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPR 289
RG G P P + G P GP GP P P G P GPR
Sbjct: 1032 GDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPR 1091
Query: 290 GSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRD 349
G + + G GA
Sbjct: 1092 G-----------------------------DKGETGERGA-------------------- 1102
Query: 350 SDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRP-PETEPGPPAP 408
G +GHR G P G++G + P P+ + P + G P P
Sbjct: 1103 ---AGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGP 1159
Query: 409 -KPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP 442
PP P +RG G+ G PG +P + GPP P AP
Sbjct: 1160 IGPPGPRGNRGERGSEGSPG-HPGQPGPPGPPGAP 1193
Score = 31.6 bits (70), Expect = 8.8
Identities = 49/194 (25%), Positives = 67/194 (34%), Gaps = 33/194 (17%)
Query: 1984 VDSQLPVVNFG---SLPPAPPPAP--PPLSLLPVGPALQPPSLAVRPPPAPATRVLP--- 2035
+D P + FG ++ P PP AP PP P GP P PP P P
Sbjct: 72 LDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPG-----PPGIPGRNGDPGIP 126
Query: 2036 ----SPARPFPASLGRA-ELHPVELKPFQDYQKLSSNL------GGPGSSRTP-PTGRSF 2083
SP P P + + P P D + S + G PG + P P G
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPG 186
Query: 2084 SGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEP 2143
+ + +P + PP A+ +GP ++G S R P
Sbjct: 187 TSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG-------PSGPAGKDGESGRPGRP 239
Query: 2144 GSRG-DKEPGLPPP 2156
G RG PG+ P
Sbjct: 240 GERGLPGPPGIKGP 253
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 154 bits (390), Expect = 7e-37
Identities = 287/1190 (24%), Positives = 385/1190 (32%), Gaps = 244/1190 (20%)
Query: 498 GAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAP-PAQ 556
G+ D PP+ P P P P PP PTP P P +
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTPSAVTPLS-PKGVTLPPKETPTPSV-----VNLPFPKE 898
Query: 557 STPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPK- 615
TP AP L S +S+S A+P +P+ P+ PP TPP PK
Sbjct: 899 GPATPAPKQAPAL-----SMTSSSPKKARATPAPKGIPASPSPK-GAPTPPAATPPSPKG 952
Query: 616 ----VEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGS 671
PK P PPS PK + P
Sbjct: 953 GPATPSPKWAPTPPAATPPS-----PKGGPATP------------------------SPK 983
Query: 672 APPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVD 731
PTP +PP P A P+P+ P PP P G P P P+ PP
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP----FPKGASTPPAAT 1039
Query: 732 PRLLQGRPPLDFYPPG--VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKL 789
P +G P P G P+ +P + G + P + AP TPP PK
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPK----GGPATPSLKGAPT--PPAATPP-SPK- 1091
Query: 790 AWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGP 849
PA P P +P+ AA TPP P A+ P P+ G P
Sbjct: 1092 --------GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143
Query: 850 PISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSG 909
P P P P P P G + TPPPK P T T P G
Sbjct: 1144 PPKGAP-TTPAATP-PSPKGG-----LATPPPKGAP---TTPAATPPSP---------KG 1184
Query: 910 GQGPPPPRRESRTETRWGPRPGS-----SRRGIPPEEPGAPPRRAGPIKKPPP---PTKV 961
G P P+ T P P S +G P PP G + P P PT
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 962 EELPPKPLEQGDETPKPPK--PDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVG 1019
PP P + G TP PPK P P T L G TPP+ +P P + V
Sbjct: 1245 AATPPSP-KGGPATP-PPKGAPTPPAATPPSLKGGLATPPHKG-APNPAV--------VT 1293
Query: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPN----H 1075
P S +G G +GA + + +G G G P
Sbjct: 1294 PPSPKG--------------GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Query: 1076 PPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV 1135
PP+P+G + S +G T PS KE PT
Sbjct: 1340 PPSPKGTPTLPATTPSS-----------KGGPT---------TPSSKEGPT--------- 1370
Query: 1136 PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPK 1195
PP A PS +GG TP PS + RG P P+ P SP L+PK
Sbjct: 1371 -----PPAATPS-------HKGGPAMTP---PSPK-RGPAIPSPKGDP-TSPAVIPLSPK 1413
Query: 1196 KPPTGPL--PPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDK 1253
K P P+ + P K L P ++PV+ + + G +
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSL--KKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 1254 PPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQN 1313
PP + ++ A S K T P P A T V P+ + +P
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPAT-----PAPMGAPTLPAVIPSSPKEVPATP------ 1520
Query: 1314 SDQANEEWETASESSDFTSERRGDKEA-PPPVLLTPKAVGTPGGGGGGAVPGISAMSRGD 1372
S + + TA+ S T KEA PP + P TP A+P
Sbjct: 1521 SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP------AIP--------- 1565
Query: 1373 LSQRAKDLSKRSFSSQRPGMERQNRRPGPGGK----AGSSGSSSGGGGGGPGGRTGPGRG 1428
+ A +S P + + P K + S S P T P
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 1429 DKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQG 1488
+ P+PK P P L P P+S V A + QA L +++G
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPAS--------VTCKMGATVPQASKGLPAKKG 1677
Query: 1489 SVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPR 1548
+ P P PTR PQ S +S P P P + P
Sbjct: 1678 PTAL-----KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC--PDPSAKNGSKGPL 1730
Query: 1549 DSAGVSPFPPKRRE-----------RPPRKPELLQEESLPPPHSSGFLGS---KPEGPGP 1594
+ +P P +++ P+ P E P ++ KPE
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790
Query: 1595 QAESRDTGTEALTPHIWNRLHTATSRKSYRPSS----MEPWMEPLSPFED 1640
A + L P + + T ++ + PSS +E +PL+P ++
Sbjct: 1791 SAAPSPPVSLPLAP---SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Score = 141 bits (356), Expect = 6e-33
Identities = 389/1675 (23%), Positives = 535/1675 (31%), Gaps = 353/1675 (21%)
Query: 509 AAPPAAPSTPAPPPAVPKELPAPPAP---------PPASAPTPETEPEEPAQAPPAQSTP 559
A P APS P + +P P ++ ++ P P P
Sbjct: 373 AFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMP 432
Query: 560 TPGVAAAPTLVSGGGSTSSTSSGSFE-ASPVEPQLPSKEGP----EPPEEVPPPTTPPVP 614
V P +V+ + ++ + +FE A+ V P P GP EP P P
Sbjct: 433 VSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSP--PMSSGPISNIEPTSPAALVMAPVAP 490
Query: 615 KVEPKGDGIGPTRQPPSQGLGYPKYQKSLPP----RFQRQQQEQLLKQQQQHQ-WQQHQQ 669
K EP R P S L P+ K+LP +F Q+ Q + + + Q
Sbjct: 491 K-EPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549
Query: 670 G---SAPPTPVP--PSPPQ--PVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPR 722
G PT +P + P+ P +P+ P P L +LG P P+
Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI-------- 601
Query: 723 WMMIPPYVDPRLLQGRPPLDFYPP-GVHPSGLVPRERSDSGGSSSEPFDRHA------PA 775
G+P P GV+ S V + S +G S+ P + + A
Sbjct: 602 --------------GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA 647
Query: 776 MLRERGTPP-VDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPY 834
E P V P A +T T + T L +G + P VP
Sbjct: 648 FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707
Query: 835 LASYPGFPENGAPGPPI---SRFPLEEPGPR--PLPWPPGS---DEVAKIQTPPPKKEPP 886
P AP + P P P P PPG+ D ++ P P
Sbjct: 708 CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP 767
Query: 887 KEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPP 946
KE + +G A + P P +T+ RP + + P+ P
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTK---RPPTKKGSAGPDTP---- 820
Query: 947 RRAGPIKKPPPPTKVEELPPKPLE-QGDE---------TPKPPK--PDPLKIT----KGK 990
G + P P + LP L QG + TP PK P P +T KG
Sbjct: 821 --IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGV 878
Query: 991 LGGPKETPP----------NGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRG 1040
PKETP G +PAP+ S P R
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA--------------- 923
Query: 1041 TYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKR 1100
T +G A +G T PP+P+G A+ + PK
Sbjct: 924 TPAPKGIPA------------SPSPKGAPTPPAATPPSPKGGPATPS----------PKW 961
Query: 1101 RRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV---PLAPPPPGAPPSPAPARFTARG 1157
+ T PS K APTP T P P P GAP PA + +G
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 1158 GRVFT--PRGV--------PSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPT------GP 1201
T P+G PS +G P P+ P +P A +PK P P
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGPATPSLKGAP 1080
Query: 1202 LPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLK 1261
PP+ P K GP +P +G M P + G A PP
Sbjct: 1081 TPPAATPPSPK--GGPATPSPKGAP-------MPPAATPPSPKGGLA----TPPH----- 1122
Query: 1262 QERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
+G P+ T A+ P P+ L T AP AA P
Sbjct: 1123 ----------KGAPT-TPAATPPSPKGGLATPPPKGAPTTPAATPP-------------- 1157
Query: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLS 1381
S + G PP T A P GG A P + A
Sbjct: 1158 ----------SPKGGLATPPPKGAPTTPAATPPSPKGGLATPS---------PKGAPTTP 1198
Query: 1382 KRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSR 1441
+ S + G+ + + P A + S GG + PSPK
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGG----------------LATPSPKGAPT 1242
Query: 1442 PPEERPP---GLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP-GGHP 1497
P PP G P PPP + + PA +L + G T P G P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAP----------TPPAATPPSL-----KGGLATPPHKGAP 1287
Query: 1498 RHKPGLPQAPQ-GPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPF 1556
P +P+ GP+ PP G + P P P +G GTP
Sbjct: 1288 NPAVVTPPSPKGGPATSPP---------KGAPTPPAATPPSP--KGSPGTP--------- 1327
Query: 1557 PPKRRERPP--RKPELLQEESLP--PPHSSG--FLGSKPEGPGPQAES-RDTGTEALTPH 1609
PPK PP P +LP P S G S EGP P A + G A+TP
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 1610 IWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGD-SQVSSGPCSQ 1668
R S K P+S P + PLSP + T +++ + GD + + P S
Sbjct: 1388 SPKRGPAIPSPKG-DPTS--PAVIPLSP-KKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 1669 RSSPDGGLKGAAEGPPKRPG--GSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQ 1726
+ +P A +G P P G L AV + P + PPAP P++
Sbjct: 1444 KKAP---ATSAPKGGPATPSSKGDPTLPAV-------TPPSPKEPPAPKQVATSSSPKKA 1493
Query: 1727 PLPPGPIGTERSQRT-DRGTEPGPIRPSHRPGPPVQFGT-SDKDSDLRLVVGDSL--KAE 1782
P P P+G + P PS R P T K + L ++L A
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553
Query: 1783 KELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAG 1842
+ T AIP ++ PS+ ++ P + + P P + L P
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK---ELLIPPAV---TS 1607
Query: 1843 PSSSQISGGAMDSQLHPNSGGFRP---GTPSLHPYRSQPLYLPP----------GPAPPS 1889
PS + + P G P GTP+ P L P G P
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 1890 ALLSGLALKG-----QFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSP------- 1937
A A KG + L ++T + P S SP CP P
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Query: 1938 -----LPDTSLLQVRQDL------PSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDS 1986
+ LL V++D S PL P P A A + +LP +S
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES 1787
Query: 1987 ------QLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLP 2035
P V+ P P PP LP P L S + PA +LP
Sbjct: 1788 ASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Score = 138 bits (347), Expect = 7e-32
Identities = 301/1273 (23%), Positives = 419/1273 (32%), Gaps = 221/1273 (17%)
Query: 111 LPASQTPASNQPKRPPAAPENT----------PLVPSGVKSWA--QASVTHGAHG-DGGR 157
LP T + N P P +P+NT P +P V S + A G DG
Sbjct: 698 LPLVPTASENCPVAP--SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755
Query: 158 ASSLLSRF--SREEFPTLQAAGDQDKAAKERES--AEQSSGPGPSLRPQNSTTWRDGGGR 213
+S L+ S +E PT + ++K + A+ S G S+ PQ G
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815
Query: 214 GPD----ELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQG 269
GPD L P S + P L G P + P PP P+G
Sbjct: 816 GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA----------TTHSPTPP--SPKG 863
Query: 270 PYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGA 329
PTP + P+G P + PS++ KE A
Sbjct: 864 A---PTPSAVTPL----SPKGVTLPPK---ETPTPSVVNLPFPKE------------GPA 901
Query: 330 HEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPK 389
L + + +G S S G PP A SP P TP
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP---SPKGGPATPS 958
Query: 390 TAWAET---SRPPETEPGPPAPKP---PLPPPHRGPAGNWGPPGDYPDRGGPP--CKPPA 441
WA T + PP + GP P P P PP P+ GP P P PP+
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018
Query: 442 PEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPD 501
P+ A + S+ A + + + A L K G
Sbjct: 1019 PKGSPAATPFPKGASTPP---AATPPSPKGSPAATPLPKGAPTTPAATLP--SPKGGPAT 1073
Query: 502 KRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPE----TEPEEPAQAPPAQS 557
LK P P A P +P PA P A P PP A+ P+P+ T P + A PA +
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 558 TPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVE 617
P+P A G +T + + S + P P K P P PP +
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP--PPKGAPTTPAATPPSPKGGLATPS 1190
Query: 618 PKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV 677
PKG P PPS PK + P AP TP
Sbjct: 1191 PKGAPTTPAATPPS-----PKGGLATP-----------------------SPKGAPTTPA 1222
Query: 678 PPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQG 737
+PP P A P+P+ P P A P G P P P+ PP P L+G
Sbjct: 1223 -ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP-----PKGAPTPPAATPPSLKG 1276
Query: 738 RPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFT 797
+ +P+ + P S GG ++ P + AP TPP PK
Sbjct: 1277 GLATPPHKGAPNPAVVTP--PSPKGGPATSP-PKGAPT--PPAATPP-SPK--------- 1321
Query: 798 ATPAEPRPLTSPLRQA-ADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPL 856
+P P P +P A KG TP +P P P P + P + P
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKG----TPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
Query: 857 EEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVG----SGGQG 912
+ GP P P P PK +P L+ +A P G S G
Sbjct: 1378 HKGGPAMTPPSPKRGPA----IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433
Query: 913 PPP-------PRRESRTETRWGPRPGSSRRGIP---------PEEPGAPPRRA---GPIK 953
PP + + + + GP SS +G P P+EP AP + A P K
Sbjct: 1434 TPPAVTPVSLKKAPATSAPKGGPATPSS-KGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Query: 954 KP--PPPTKVEELPPKPLEQGDETPKPP--KPDPLKITKGKLG-------GPKET-PPNG 1001
P P P LP E P P + DP+ T L PKE P
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
Query: 1002 NLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFR 1061
P+P+ + P + + E + TY G +E
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSK---EASSPPAVTPSTYKG---APSPKELLIPPAVT 1606
Query: 1062 GDDGRGGGTGGPNHPPAP-RGRTASETRSEGSEYEEIPKRRRQRGSETGSETHE--SDLA 1118
+ T PP+P +G + + P + + S T + + +
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666
Query: 1119 PSDKEAPTPKEGT-LTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRP 1177
+ K P K T L +V +AP P P AP R +G +++
Sbjct: 1667 QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR-----------KGPQTKK---SSAT 1712
Query: 1178 PPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDG 1237
P +CP P AK+ SK PL + P PL PV + S
Sbjct: 1713 SPPICP--DPSAKN------------GSKGPL-STVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 1238 ER-PRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVA 1296
+ P +A F ++ + E+A+ + P ++LP AP P V
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-APSP------VPTL 1810
Query: 1297 PAPRRAAAKSPDL 1309
P ++ SP L
Sbjct: 1811 PPKQQFLPSSPGL 1823
Score = 131 bits (329), Expect = 8e-30
Identities = 266/1153 (23%), Positives = 363/1153 (31%), Gaps = 231/1153 (20%)
Query: 77 SLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVP 136
S +P++ + ++ P ++ + T P+ P P++ TP S PK P+ TP
Sbjct: 834 SFLPENSLSFQGSKDS--PATTHSPTPPSPKGAPTPSAVTPLS--PKGVTLPPKETP--- 886
Query: 137 SGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAE----QS 192
SV + G A+ + ++ P L K A+ + +
Sbjct: 887 -------TPSVVNLPFPKEGPATP-----APKQAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 193 SGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGL-------QPSGPPQFPP 245
S G P + GG P P P+GG P+ P PP
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 246 YRGMMPPFMYPPYLPFPP---PYGPQG-PYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPV 301
P P P PP P P+G P P P G S P P G P P
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 302 GRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDS 361
G P+ + +G +
Sbjct: 1055 GAPTT-----------------------------------------PAATLPSPKGGPAT 1073
Query: 362 QSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP------PP 415
S G PP A PP+PK A S P+ P PPA PP P PP
Sbjct: 1074 PSLKGAPTPPAA----------TPPSPKGGPATPS--PKGAPMPPAATPPSPKGGLATPP 1121
Query: 416 HRG----PAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRR 471
H+G PA PP +GG PP A S + LA +
Sbjct: 1122 HKGAPTTPAAT--PPS---PKGGLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAP 1172
Query: 472 EEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPA--------APPAAPSTPAPPPA 523
+ K GAP P+ +P AP+TPA P
Sbjct: 1173 TTPAATPPSPKGGLATPSPK------GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Query: 524 VPK---ELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTS 580
PK P+P P A TP + PA PP + PTP A P+L GG +
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPA-TPPPKGAPTPPAATPPSL--KGGLATPPH 1283
Query: 581 SGSFEASPVEPQLPSKEGP--EPPE--EVPPPTTPPVPK-----VEPKGDGIGPTRQPPS 631
G+ + V P P K GP PP+ PP TPP PK PKG P PPS
Sbjct: 1284 KGAPNPAVVTPPSP-KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 632 QGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPP-------SPPQP 684
PK +LP + ++G PP P +PP P
Sbjct: 1343 -----PKGTPTLPATTPSSKGGPTTPSS--------KEGPTPPAATPSHKGGPAMTPPSP 1389
Query: 685 VTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFY 744
A+P+P+ P P A+ P + + P P V D
Sbjct: 1390 KRGPAIPSPKGDPTSP-AVIPLSPKKAPATP--------------VTREGAATPSKGDLT 1434
Query: 745 PPGVHPSGL--VPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAE 802
PP V P L P + GG PA +G P + TP
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGG----------PATPSSKGDPTLP----------AVTPPS 1474
Query: 803 PRPLTSPLRQAADEDDKGMRSETPPVPPPPPYL-ASYPGFPENGAPGPPISRFPLEEPG- 860
P+ +P + A K ++ P P P L A P P+ P R P+
Sbjct: 1475 PKEPPAPKQVATSSSPK--KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 861 ----PRPLPWPPGSDEVAKIQT-PPPKKEP----PKEETAQLTGPEAGRKPARGVGSGGQ 911
P P + T P PKK P PKE A + EA PA +
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 912 GPPP-----PRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPP 966
P P P + + P P + P + P P + P P P+ +++ P
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Query: 967 KP----LEQGDETPKPPKPDPLK----ITKGKLGGPKETPPNGNLSPAPRLRRDYSYERV 1018
P + G P+ K P K K L P P + + AP R
Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP--APESTPIITAP--------TRK 1702
Query: 1019 GPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRG-GGTGGPNHPP 1077
GP + + + G ++ +G + P P
Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762
Query: 1078 APRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVP- 1136
AP AS + + + +PK S S LAPS PK+ L P
Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG 1822
Query: 1137 LAPPPPGAPPSPA 1149
L P P +PA
Sbjct: 1823 LVLESPSKPLAPA 1835
Score = 120 bits (302), Expect = 1e-26
Identities = 244/1056 (23%), Positives = 335/1056 (31%), Gaps = 152/1056 (14%)
Query: 6 GPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLPSL 65
G T K+ S +NL +G + K A A S K AR P P +P+
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK---ARATPAPKGIPAS 933
Query: 66 KAENKGNDPNVSLVPKDGTG-------WASKQEQSDPKSSDASTAQP-PESQPLPASQTP 117
+ P + P G WA + P S A P P+ P P + TP
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 118 ASNQPKRPPA--APENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQA 175
S PK PA +P+ P P+ + S G + S + P A
Sbjct: 994 PS--PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP---A 1048
Query: 176 AGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGG- 234
A K A +A S G P P GP + P+G
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP-----SPKGAP 1103
Query: 235 LQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPP 294
+ P+ P P PP P P P P+G P P G P P G
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG- 1162
Query: 295 MRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEG 354
+ P G P+ L + G + K +
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 355 AEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPP--- 411
A S G P G +P + PP+PK A + PP+ P PPA PP
Sbjct: 1223 AT----PPSPKGGLATPSPKGAP-TTPAATPPSPKGGPA--TPPPKGAPTPPAATPPSLK 1275
Query: 412 ---LPPPHRG--------PAGNWGPPGDYPDRGGPP---CKPPAPEDEDEAWRQRRKQSS 457
PPH+G P G P P +G P PP+P+ + +
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
Query: 458 SEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPST 517
++ + K G K P P A PS
Sbjct: 1336 PAVT-----------------PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 518 ---PAPPPAVPKELPAPPAPP-----PASAP-TPETEPEEPAQ----APPAQSTPTPGVA 564
PA P PK PA P+P PA P +P+ P P A P++ TP A
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP-A 1437
Query: 565 AAPTLVSGGGSTSSTSSG-SFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI 623
P + +TS+ G + +S +P LP+ P P E PP PK
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE--PPAPKQVATSSSPKKAPA 1495
Query: 624 GPTRQ-PPSQGLGYPKYQKSLP--PRFQRQ--QQEQLLKQQQQHQWQQHQQGSAPPTPVP 678
P P+ P K +P P +R L ++ ++ PP
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 679 PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNF----DPRWMMIPPYVDPRL 734
PSP + A+P P+ P P + + PP + P + P+ ++IPP V
Sbjct: 1556 PSPKK---TPAIPTPKEAPATPSSKEASS---PPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Query: 735 LQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGT---PPVDPKLAW 791
+ P PP V P P PA +GT PPV P
Sbjct: 1610 PKEAPT----PPAVTP-----------------PSPEKGPATPAPKGTPTSPPVTP---- 1644
Query: 792 VGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYP-GFPENGAP--- 847
+P P +T + + KG+ ++ P +A P P AP
Sbjct: 1645 --SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK 1702
Query: 848 GPPISRFPLEEPGPRPLPWPP-GSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGV 906
GP + P P P GS P P K+ + G +A P
Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK--- 1759
Query: 907 GSGGQGPPPPRRESRTETRWG-----PRPGSSRRGIPPEEPGAPPRRAGPIKKPPP---- 957
G PP + S T P+P S+ P P + P P+ PP
Sbjct: 1760 ---GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQF 1816
Query: 958 ----PTKVEELPPKPLEQGDETPKPPKPDPLKITKG 989
P V E P KPL DE P P I+ G
Sbjct: 1817 LPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852
Score = 114 bits (286), Expect = 8e-25
Identities = 374/1720 (21%), Positives = 536/1720 (31%), Gaps = 296/1720 (17%)
Query: 506 AEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTP--GV 563
A A+P +PST A + P E+P P + + P T PE P P P +
Sbjct: 61 ANQASPFPSPSTIA---STPLEVPFPQSSSGTALPLG-TAPEAPTFLPNLIGPPISPAAL 116
Query: 564 AAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTT------------- 610
A A +++ + +SS + P K PP + P +
Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176
Query: 611 PPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQG 670
P+ EPK + + PS+ + PK S PP + Q
Sbjct: 177 APIAPSEPKTN----LNKVPSEVVPNPKGTPS-PPCIVSTVPYHCVTPMASIQ---SGVA 228
Query: 671 SAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALY-----PGALG-RPPPMPPMNFDPRWM 724
S P T P T A+ +PQ ++ PG+L + P PP
Sbjct: 229 SLPQTT-------PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQ 281
Query: 725 MIPPYVDPRLLQG-RPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP 783
+P + G P DF P S L P +S G S + + P+ L +
Sbjct: 282 SLPVVTSSQKTAGPNTPPDF--PISLGSHLAPLHQSSFG--SVQLLGQTGPSALSDPTVK 337
Query: 784 PVDPKLAWVGDVFTATPAEPRPLTS-----PLRQAA-----DEDDKGMRSETPPVPPPPP 833
+ + G + + + PL S P AA DKG + + P
Sbjct: 338 TISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSG 397
Query: 834 YLASYPGF-------------PENGAPGPPISRFPLEEPGPRPL---------PWPPGSD 871
L F P P +++ P+ G PL P +
Sbjct: 398 SLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTF 457
Query: 872 EVAKIQTPPPKKEP-----PKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRW 926
EVA +PP P P A + P A ++P+ V + + P P + +
Sbjct: 458 EVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLK- 516
Query: 927 GPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKI 986
P S P ++ P +E P P + G T K P PL
Sbjct: 517 -NLPSSVLVKFPTQKD-----------LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLV- 563
Query: 987 TKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRG 1046
PK +P + S +P + + + GE G+ G
Sbjct: 564 ----QAAPKNSPSFQSTSSSPEIPLSPE------ATLAKKSLGEPLPIGKPASSMTSPLG 613
Query: 1047 RGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS 1106
+ + ++ D G + GP + T + E ++ + + S
Sbjct: 614 VNSSASVIKT------DSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTS 667
Query: 1107 E---TGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPP-GAPPSPAPARFTARGGRVFT 1162
T S E ++ + K P KEGTLT +PL P P +P+P A +
Sbjct: 668 TYTTTASPFLEGTVSLAPKNHPV-KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726
Query: 1163 ----PRGVPSRRGRGGGRPP--------------------PQVCPGWSPPAKSLAPKKPP 1198
P+ VPS G PP P+ CP A + A K
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786
Query: 1199 TGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFR 1258
L S PL + P P + GS G G P
Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP------------IGNLSSPVSPVEAS 834
Query: 1259 RLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSP---------DL 1309
L E + +GS+ P+ T + P P+ A T V P + P +L
Sbjct: 835 FLP-ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 1310 SNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLL----------TPKAVGTPGGGGG 1359
A + A S +S + + P P + TP A P GG
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 1360 GAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGG----- 1414
A P + A + S + G + + P A + S GG
Sbjct: 954 PATPS---------PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 1415 --GGGGPGGRTGPG-RGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHS 1471
G P T P +G + P PK S PP PP P S A L + +
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS------PKGSPAATPLPKGAPT 1058
Query: 1472 NPAGIQQALAQLSSRQGSVTAPG--GHPRHKPGLPQAPQG----PSPRP---PTRYEPQR 1522
PA A L S +G P G P P +P+G PSP+ P P
Sbjct: 1059 TPA------ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 1523 VNSGLSSDPHFEEPG------PMVRG------VGGTPRDSAGVSPFPPKRRERPPRKPEL 1570
GL++ PH P P +G G P A P P PP K
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172
Query: 1571 LQEESLPPPHSSGFLGSKPEG----PGPQAESRDTGTEALTPHIWNRLHTAT-------- 1618
+ PP G P+G P S G +P AT
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232
Query: 1619 SRKSYRPSSMEPWMEPLSPFEDVA-----GTEMSQSDSGVDLSGDSQV---SSGPCSQRS 1670
+ S + + P P SP A G + + L G P
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPC--EGPPGSEPPRRPP--PAPHDGDRKELPREQ 1726
+P G A PPK G +P A P +G PG+ PP+ P PA K P
Sbjct: 1293 TPPSPKGGPATSPPK--GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350
Query: 1727 PLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLK-AEKEL 1785
P G + + G P PSH+ GP + + + + GD A L
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410
Query: 1786 TASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSS 1845
+ A PV+R+ PS P + P++S + GP++
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA---PATSAPK---------GGPAT 1458
Query: 1846 SQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFS 1905
G + P S P P S P P PAP A + +
Sbjct: 1459 PSSKGDPTLPAVTPPSPK-EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Query: 1906 TMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGG 1965
++ + P + L S + P +L+ +PSP TP P
Sbjct: 1518 ATPSSRRDPIA-------PTATLLSKKTPATLAPKEALIPPAMTVPSPK---KTPAIP-- 1565
Query: 1966 QSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPP-----APPPLSLLPVGPALQPPS 2020
P APA P S PPA P AP P LL + PA+ PS
Sbjct: 1566 ----TPKEAPAT-----------PSSKEASSPPAVTPSTYKGAPSPKELL-IPPAVTSPS 1609
Query: 2021 LAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQD 2060
P P T P PA G PV +D
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Score = 95.1 bits (235), Expect = 6e-19
Identities = 223/959 (23%), Positives = 315/959 (32%), Gaps = 170/959 (17%)
Query: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
PP A PS K P + +P T + K + P A T P + P P
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT-PAATPPSPKGGL 1140
Query: 117 PASNQPKRPPAAPENTPLVPSGVKSWAQ---ASVTHGAHGDGGRASSLLSRFSREEFPTL 173
A+ PK P P TP P G + A T A + L+ S + PT
Sbjct: 1141 -ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG--LATPSPKGAPTT 1197
Query: 174 QAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRG 233
AA + + + P+ P + GG P P + P+G
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPK----GGLATPSPKGAPTTPAATPPSPKG 1253
Query: 234 GLQPSGPPQFPPYRGMMPPFMYPPYLP----FPPPYGPQGPYRYPTPDGPSRFPRVAGPR 289
G P+ PP P PP PP L PP G P TP P P + P+
Sbjct: 1254 G--PATPP---PKGAPTPPAATPPSLKGGLATPPHKGAPNP-AVVTPPSPKGGPATSPPK 1307
Query: 290 GSGPPMRLV--EPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347
G+ P P G P + + G T L
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG----------TPTLP------- 1350
Query: 348 RDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPA 407
+ ++G + S+ PP A P PP+PK A S P+ +P PA
Sbjct: 1351 --ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSPA 1406
Query: 408 PKPPLPPPHRGPAGNWGPPG-DYPDRGG--PPCKPPAPEDEDEAWRQRRKQSSSEISLAV 464
P P + PA G P +G PP P + A + ++ S
Sbjct: 1407 VIP--LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464
Query: 465 ERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAV 524
+ ++ A + + K+ A P AP AP+ PA P+
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATS-----------SSPKKAPATP-APMGAPTLPAVIPSS 1512
Query: 525 PKELPAPPA------PPPA---SAPTPETEPEEPAQAPPAQSTPTP-GVAAAPTLVSGGG 574
PKE+PA P+ P A S TP T + A PPA + P+P A PT
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 575 STSSTSSGSFEA----------SPVEPQLP-------SKEGPEPPEEVPP---------- 607
+ SS + S A SP E +P KE P PP PP
Sbjct: 1573 TPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632
Query: 608 ----PTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
PT+PPV K P G P+ K LP + +++L
Sbjct: 1633 PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP---- 1688
Query: 664 WQQHQQGSAPPTPVPPSP----PQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNF 719
+ TP+ +P PQ A P P P K G L P P
Sbjct: 1689 -------APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP---- 1737
Query: 720 DPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAP----A 775
++P D P G L P E S ++ F++ P A
Sbjct: 1738 -----LLPVQKDSSKTAKGKDASHSPKG----PLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 776 MLRERGTPPVDPKLAWVGDVFTATPAEPRPL-TSPLRQAADEDDKGMRSETPPVPPPP-- 832
+ +PPV + P P P+ T P +Q G+ E+P P P
Sbjct: 1789 SVSAAPSPPV------------SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836
Query: 833 --PYLASYPGFPENGAPGPPISRFPLEEPGPR----PLPWPPGSDEVAK------IQTPP 880
L P P +G G P + P P+ P+P P V K ++
Sbjct: 1837 EDELLPLIPPEPISG--GVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDS 1894
Query: 881 PKKEPPKEE--TAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGI 937
+ P EE + Q T +A A + + P ++SR+E + R S+ G+
Sbjct: 1895 DESVPELEEQDSTQATTQQAQLAAAAEI---DEEPVSKAKQSRSEKK--ARKAMSKLGL 1948
Score = 91.7 bits (226), Expect = 7e-18
Identities = 240/1106 (21%), Positives = 341/1106 (30%), Gaps = 157/1106 (14%)
Query: 1117 LAPSDKEAPTPKEGTLTQVPLAPPPPGAP-----PSPAPARFTARGGRVFTPRGV----- 1166
+AP + P+ + T ++P++PP P PS +F + P +
Sbjct: 485 MAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPF 544
Query: 1167 -PSRRGRGGGRPPP-----QVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSP 1220
P++ G + P Q P SP +S + P PL P K+ L G P
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSS--PEIPLSPEATLAKKSL--GEPLP 600
Query: 1221 VARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLP 1280
+ + S+ S +G+ + P L A P+ P
Sbjct: 601 IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 1281 ASAPGPEEALTTV------TVAPAPRRAAAKSPDLS--------NQNSDQANEEWETASE 1326
+A G TT TV+ AP+ K L+ ++N A T +
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 1327 SSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQR---AKDLSKR 1383
+ K P P L P A PG + SA++ S + +D
Sbjct: 721 LATLVLAPEIPKSVPSPSL--PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778
Query: 1384 SFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPP 1443
+ +S + + P P G + S + G G P G+ S SP S P
Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTP-IGNLSSPVSPVEASFLP 837
Query: 1444 EER--------PPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGG 1495
E P P PPS V +P G+ + + V P
Sbjct: 838 ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT-PSVVNLP-- 894
Query: 1496 HPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSP 1555
P+ P P Q P+ S SS P P +G+ +P +P
Sbjct: 895 FPKEGPATPAPKQAPAL------------SMTSSSPKKARATPAPKGIPASPSPKG--AP 940
Query: 1556 FPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPG-PQAESRDTGTEALTPHIWNRL 1614
PP P+ P + S GP P + T A P
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
T + + + P P + P SP A T + S + P +
Sbjct: 1001 ATPSPKGAPTP----PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
AA P + G ++P +G P PP PP+P G P+ P+PP
Sbjct: 1057 PTTPAATLPSPKGGPATP----SLKGAP--TPPAATPPSPKGGPATPSPKGAPMPPAA-- 1108
Query: 1735 TERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIP 1794
T + G P H+ P T G + + A P
Sbjct: 1109 ------TPPSPKGGLATPPHKGAPTTPAATPPSPK------GGLATPPPKGAPTTPAATP 1156
Query: 1795 VSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMD 1854
S L A P K + PS G G A PS G
Sbjct: 1157 PSPKGGL-------ATPPPKGAPTTPAATPPSPKG---------GLATPSPK---GAPTT 1197
Query: 1855 SQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGK 1914
P S TPS + P PP P GLA +T AT
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPS- 1250
Query: 1915 LPAGGVLYPPPSFLYSP-AFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSG 1973
P GG PPP +P A P L + P+P+ + P GG + P G
Sbjct: 1251 -PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA-VVTPPSPKGGPATSPPKG 1308
Query: 1974 APAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRP-----PPA 2028
AP P P G+ PP P PP ++ P P P A P P
Sbjct: 1309 APTPPAATPPSPKGSP----GTPPPKGAPTPPAVT--PPSPKGTPTLPATTPSSKGGPTT 1362
Query: 2029 PATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNS 2088
P+++ P+P P+ G + P K + S G P S P
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGP---AIPSPKGDPTSPAVIPLSPK------ 1413
Query: 2089 RLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTG------------------P 2130
+ ATP T G + DL A P +L+ P G P
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473
Query: 2131 PPREGPSRRAEEPGSRGDKEPGLPPP 2156
P+E P+ + S K P P P
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAP 1499
Score = 37.7 bits (86), Expect = 0.12
Identities = 57/225 (25%), Positives = 75/225 (33%), Gaps = 44/225 (19%)
Query: 495 EKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPA-QAP 553
E A ++ L A P + A P P PPP S P P+ P A QA
Sbjct: 7 ETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCS-PAPQQCPLSAANQAS 65
Query: 554 PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV 613
P S T +A+ P V S+S T+ LP PE P +P PP+
Sbjct: 66 PFPSPST--IASTPLEVPFPQSSSGTA------------LPLGTAPEAPTFLPNLIGPPI 111
Query: 614 ---------PKVEPKGDGIGPTRQPPS-QGLGYPKYQKS--LPPRFQRQQQEQLLKQQQQ 661
P + P G + P + L QKS PP +
Sbjct: 112 SPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA---- 167
Query: 662 HQWQQHQQGSAPPTPVPPSPPQP------VTLGAVPAPQAPPPPP 700
+ GS P +P +P V VP P+ P PP
Sbjct: 168 ------ESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/146 (28%), Positives = 57/146 (39%), Gaps = 39/146 (26%)
Query: 1919 GVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQ 1978
G PPP SPA PL S PSPS STPL+ +P +
Sbjct: 42 GPTLPPPC---SPAPQQCPL---SAANQASPFPSPSTIASTPLE-------VPFPQSSSG 88
Query: 1979 MLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLP--VGPALQPPSLAVRPPP-APATRVLP 2035
LP+ G+ P AP + LP +GP + P +LA+ P AP + P
Sbjct: 89 TALPL----------GTAPEAP-------TFLPNLIGPPISPAALALASPMIAPTLKGTP 131
Query: 2036 SPARPF------PASLGRAELHPVEL 2055
S + P P S+ ++ P L
Sbjct: 132 SSSAPLALVALAPHSVQKSSAFPPNL 157
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 152 bits (383), Expect = 4e-36
Identities = 309/1277 (24%), Positives = 371/1277 (29%), Gaps = 301/1277 (23%)
Query: 346 DGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP----------------- 388
D + EG +G + G PP DG G PP P
Sbjct: 104 DQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQL 163
Query: 389 KTAWAETSRPPETEPGPPAPKPPL----PPPHRGPAGNWGPPGDYPDRG--------GPP 436
+ E S + PGP P P PP GP G GPPG+ + G GPP
Sbjct: 164 SYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP 223
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496
P D+ EA + R ER + + L
Sbjct: 224 GPPGKNGDDGEAGKPGRPG-------------------------ERGPPGPQGARGLPGT 258
Query: 497 FGAPDKR-----LKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQ 551
G P + + A A P+ P P P E AP P P P P
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318
Query: 552 APPAQSTPTPGVAA--APTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPT 609
A + G A PT +G EA P P+ G E P+ V
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR-----GSEGPQGVRGEP 373
Query: 610 TPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQ 669
PP P GP P + G K P
Sbjct: 374 GPPGP-----AGAAGPAGNPGADGQPGAKGANGAPGI----------------------- 405
Query: 670 GSAPPTPVPPSPPQPVTLGAVPAPQA----PPPPPKALYPGALGRPPPMPPMNFDPRWMM 725
AP P P P G P P+ P P GA G P P+
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG---------- 455
Query: 726 IPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPV 785
+QG PPG P G+ EP P ERG P
Sbjct: 456 ---------VQG-------PPG-------PAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492
Query: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-EN 844
G PA R P + G E P L PG P +
Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL--PGAKGLTGSPGSPGPD 550
Query: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKK----EPPKEETAQLTGPEAGR 900
G GPP PGP P PPG+ A + P K EP K + GP
Sbjct: 551 GKTGPPGPAGQDGRPGP---PGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAV 607
Query: 901 KPARGVG-SGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPT 959
PA G +G QGPP P + GP +G+P P PP AG
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPG--PAGPPGEAG--------- 656
Query: 960 KVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVG 1019
KP EQG G LG P G
Sbjct: 657 -------KPGEQG--------------VPGDLGAP------------------------G 671
Query: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRG-RGARSREFRSYREFRGDDGRGGGTGGPNHP-- 1076
P+ RG RG F RG +G G G RGA G+DG G G P P
Sbjct: 672 PSGARGE-RG--FPGERGVQGPPGPAGPRGANGAP--------GNDGAKGDAGAPGAPGS 720
Query: 1077 ------------------PAPRGRT--ASETRSEGSEYEEIPKRRRQRG--------SET 1108
P P+G A ++GS P + RG
Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS-----PGKDGVRGLTGPIGPPGPA 775
Query: 1109 GSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTP--RGV 1166
G+ + + PS PT G AP G P P PA F G P +G
Sbjct: 776 GAPGDKGESGPSGPAGPTGARG-------APGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828
Query: 1167 PSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGS 1226
P G G PP PP P S P PG V G
Sbjct: 829 PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGP 888
Query: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFR--RLKQERENAARGSEGKPSLTLPASAP 1284
+G N G P + G+ + + P R + G +G P PA AP
Sbjct: 889 SG--NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946
Query: 1285 GPEEALTTVTVAPAPRRAAAKSP--DLSNQNSDQA-----NEEWETASESSDFTSERRGD 1337
G P P+ A + L Q ++ E + S RG
Sbjct: 947 G----------TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG- 995
Query: 1338 KEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNR 1397
PP + P G PG G PG D S AK + + PG
Sbjct: 996 ---PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052
Query: 1398 RPGPGGKAGSSGSSSGGGGGGPGGRTGP-----------GRGDKRSWPSPKNRSRPPEER 1446
PGP G AG SG G GP G GP RGDK +R
Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRG 1112
Query: 1447 PPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--------LSSRQGSVTAPGGHPR 1498
GL PP PP S S PAG + L+ G + PG R
Sbjct: 1113 FSGLQGPPGPPGSPG--EQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170
Query: 1499 HKPGLPQAPQGPSPRPP 1515
P P GP P PP
Sbjct: 1171 TGDAGPVGPPGP-PGPP 1186
Score = 135 bits (340), Expect = 4e-31
Identities = 331/1333 (24%), Positives = 398/1333 (29%), Gaps = 346/1333 (25%)
Query: 508 PAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAP 567
PA PP P P LP PP PP P PG+
Sbjct: 125 PAGPPGRDGIPGQPG-----LPGPPGPPGPPGP--------------------PGL---- 155
Query: 568 TLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTR 627
GG S G E S +P GP P +P GP
Sbjct: 156 ----GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLP-----------------GPPG 194
Query: 628 QPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTL 687
P QG P P P +P
Sbjct: 195 APGPQGFQGP----------------------------------------PGEPGEPGAS 214
Query: 688 GAVPAPQAPPPPP----------KALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQG 737
G + P+ PP PP K PG G P P P +P R G
Sbjct: 215 GPM-GPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL-PGTAGLPGMKGHRGFSG 272
Query: 738 RPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVD-PKLAWVGDVF 796
LD P+G P+ S G + P + ERG P P A D
Sbjct: 273 ---LDGAKGDAGPAG--PKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327
Query: 797 TATPAEPRPL-----------------TSPLRQAADEDDKGMRSETPPVPPPPPYLASYP 839
T P P P E +G+R E P PP P A
Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE--PGPPGPAGAAGPA 385
Query: 840 GFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTP---PPKKEPPKEETAQLTGP 896
G P GA G P ++ PG P PG+ + Q P P K E A +
Sbjct: 386 GNP--GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKG 443
Query: 897 EAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPP 956
+ G K G G QGPP P E G R G P PG P R GP +
Sbjct: 444 DTGAKGEPGP-VGVQGPPGPAGEE------GKRGARGEPG-PTGLPGPPGERGGPGSRGF 495
Query: 957 PPTKVEELPPKPL-EQGDETPKPPKPDP----------LKITKGKLGGPKETPPNGNLSP 1005
P P P E+G P PK P L KG G P P+G P
Sbjct: 496 PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555
Query: 1006 APRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDG 1065
+D GP RG+ A GF G G G ++ E R G G
Sbjct: 556 PGPAGQDGRPGPPGPPGARGQ------AGVMGFPGPKGAAGEPGKAGE----RGVPGPPG 605
Query: 1066 RGGGTG--------GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDL 1117
G G GP P P G + + ++ +P G E G +
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG-EAGKPGEQG-- 662
Query: 1118 APSDKEAPTP-----KEGTLTQVPLAPPPPGAPP---SPAPARFTARGGRVFTPRGVPSR 1169
P D AP P + G + + PP A P + AP A+G G P
Sbjct: 663 VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA-----GAPGA 717
Query: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPK--KPPTGPLPPSKEPLKEKL--IPGPLSPVARGG 1225
G G P Q PG A PK + GP P K+ + + GP+ P G
Sbjct: 718 PGSQGA-PGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG 776
Query: 1226 SNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPG 1285
+ G G G A G G+P PA G
Sbjct: 777 APGDKGESGPSGPAGPTGARG---------------------APGDRGEPGPPGPAGFAG 815
Query: 1286 PEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVL 1345
P A P A AK GD P P
Sbjct: 816 PPGADGQPGAKGEPGDAGAK------------------------------GDAGPPGPA- 844
Query: 1346 LTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKA 1405
G PG G PG +RG ++ PG + PGP G A
Sbjct: 845 ---GPAGPPGPIGNVGAPGAKG-ARGSAGPPG--------ATGFPGAAGRVGPPGPSGNA 892
Query: 1406 GSSGSSSGGG---GGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAV 1462
G G G G GP G TGP RP E PPG P P S
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPA-------------GRPGEVGPPGPPGPAGEKGSPGA 939
Query: 1463 FRLDQVIHSNPAGIQQALAQ--LSSRQGSVTAPGGH-PRHKPGLPQAPQGPSPRPPTRYE 1519
PAG ++ ++G V PG R PGLP GPS P
Sbjct: 940 --------DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP----GPSGEPG---- 983
Query: 1520 PQRVNSGLSSDPHFEEPGPM-VRGVGGTP----RDSAGVSPFPPKRRERPPRKPELLQEE 1574
++ SG S + PGPM G+ G P R+ A + P R P K + +
Sbjct: 984 -KQGPSGASGERG--PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETG 1040
Query: 1575 SLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEP 1634
PP + G G+ P GP +S D G A P P
Sbjct: 1041 PAGPPGAPGAPGA-PGPVGPAGKSGDRGETG----------PAGPAGPVGPVGARGPAGP 1089
Query: 1635 LSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSP-DGGLKGAA-----EGPPKRPG 1688
P D G Q D G+ GP SP + G GA+ GPP G
Sbjct: 1090 QGPRGD-KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148
Query: 1689 --GSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTE 1746
G LN +P GP G PP P P P PPGP
Sbjct: 1149 APGKDGLNGLP--GPIG-------PPGPRGRTGDAGPVGPPGPPGP-------------- 1185
Query: 1747 PGPIRPSHRPGPP 1759
PGP PGPP
Sbjct: 1186 PGP------PGPP 1192
Score = 127 bits (320), Expect = 9e-29
Identities = 307/1172 (26%), Positives = 364/1172 (31%), Gaps = 278/1172 (23%)
Query: 195 PGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFM 254
PGP P GG P G D K G G + PSGP RG+
Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP------RGL----- 189
Query: 255 YPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRG-SGPPMRLVEPVGRPSILKEDNLK 313
P P G GP + P G P +GP G GPP G P
Sbjct: 190 -------PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP-------GPPG-------- 227
Query: 314 EFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEA 373
+ DDG AG + GR E G G + ++ G P
Sbjct: 228 ------KNGDDGEAG----------------KPGRPG-ERGPPGPQGARGLPGTAGLPGM 264
Query: 374 DGKKGNS-------------PNSEPPTPKTAWAETSRPPETEPG----PPAPKPPLPPPH 416
G +G S P EP +P A P PG P AP P +
Sbjct: 265 KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324
Query: 417 RGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEER 476
G G GPPG GPP P A + EA Q + S + E
Sbjct: 325 DGATGAAGPPGP-TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP---------- 373
Query: 477 RMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPA-VPKELPAPPAPP 535
G P A PA P A P A + P P
Sbjct: 374 ---------------------GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412
Query: 536 PASAPTPETEPEEPAQAP-PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
A P + P+ P P P ++ PG AP GS T + E PV Q P
Sbjct: 413 GARGP---SGPQGPGGPPGPKGNSGEPG---AP------GSKGDTGAKG-EPGPVGVQGP 459
Query: 595 ----SKEGPEPPEEVPPPTTPPVPKVE---------PKGDGI-GPTRQPPSQGLGYPKYQ 640
+EG P PT P P E P DG+ GP +G P
Sbjct: 460 PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP 519
Query: 641 KSLPPRFQRQQQEQL-----LKQQQQHQWQQHQQGSAPPT-----PVPPSPPQ------- 683
K P R + L L + G P P PP PP
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579
Query: 684 ---PVTLGAVPAP-----QAPPPPPKALYP-------GALGRPPPMPPMN--------FD 720
P GA P + P PP A+ P GA G P P P
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGS 639
Query: 721 PRWMMIPPYVDPRLLQGRP-----PLDFYPPGVHPSGL-----VPRERSDSG-------- 762
P + +P P G+P P D PG PSG P ER G
Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGVQGPPGPAGPR 697
Query: 763 ------GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADE 816
G+ D AP +G P + G P R P
Sbjct: 698 GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP 757
Query: 817 DDKGMRSETPPVPPPPPYLA------SYPGFP--ENGAPGPPISRFPLEEPGPRPLPWPP 868
G+R T P+ PP P A S P P GA G P R PGP PP
Sbjct: 758 GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP 817
Query: 869 GSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGP 928
G+D P K EP GP PA GPP P G
Sbjct: 818 GAD-----GQPGAKGEPGDAGAKGDAGPPGPAGPA--------GPPGPIGNVGAPGAKGA 864
Query: 929 RPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITK 988
R + PP G P AG + PP P+ P P G E K P+ +
Sbjct: 865 RGSAG----PPGATGF-PGAAGRV-GPPGPSGNAGPPGPPGPAGKEGGKGPRGE-----T 913
Query: 989 GKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
G G P E P G PA S GP G + A RG G G RG
Sbjct: 914 GPAGRPGEVGPPGPPGPA---GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG-- 968
Query: 1049 ARSREFRSYREFRGDDGRGG--GTGGPNHPPAPRGRTA-----SETRSEGSEYEE----- 1096
R F G+ G+ G G G PP P G E+ EG+ E
Sbjct: 969 --ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGR 1026
Query: 1097 --IPKRRRQRGSETGSETHESDLAPSDKEAPTP-----KEGTLTQVPLAPPPPGAPPSPA 1149
P + RG ETG AP AP P K G + P P P P
Sbjct: 1027 DGSPGAKGDRG-ETGPAGPPG--APGAPGAPGPVGPAGKSGDRGET--GPAGPAGPVGPV 1081
Query: 1150 PARFTA-----RGGRVFT----PRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPP 1198
AR A RG + T RG+ RG G G P P PG P+ + P P
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGP-AGP 1140
Query: 1199 TGPLPPSKEPLKEKL--IPGPLSPVARGGSNG 1228
GP + P K+ L +PGP+ P G G
Sbjct: 1141 RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTG 1172
Score = 99.0 bits (245), Expect = 4e-20
Identities = 280/1153 (24%), Positives = 361/1153 (31%), Gaps = 197/1153 (17%)
Query: 91 EQSDPKSSDASTAQPPESQPLPASQTPASNQPKRP----PAAPENTPLVPS-----GVKS 141
E +P +S + P P + +P RP P P+ +P G+K
Sbjct: 207 EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266
Query: 142 WAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD-------------KAAKERES 188
S GA GD G A S E G + A+ +
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG 326
Query: 189 AEQSSGP-------GPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDP--RGGLQPSG 239
A ++GP GP P + G +GP EGP P G P+G
Sbjct: 327 ATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386
Query: 240 PPQFPPYRGMM-----PPFMYPPYLPFPP-PYGPQGPYRYPTPDGPSRFPRVAGPRGSGP 293
P G P P P P GPQGP P P G S P G +G
Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446
Query: 294 PMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEE 353
PVG ++G GA E T E
Sbjct: 447 AKGEPGPVGVQG-----------PPGPAGEEGKRGARGEPGPTGL--------PGPPGER 487
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL- 412
G G R A G P G++G SP P PK + E RP E G P K
Sbjct: 488 GGPGSRGFPGADGVAGPKGPAGERG-SPG--PAGPKGSPGEAGRPGEA--GLPGAKGLTG 542
Query: 413 PPPHRGPAGNWGPPG--DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVER---- 466
P GP G GPPG R GPP P A K ++ E A ER
Sbjct: 543 SPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPG 602
Query: 467 ----ARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPP 522
++ E Q A + G+P + PA PP P
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPG-EQ 661
Query: 523 AVPKELPAPPAPPPASAPTPETEP-EEPAQAPPAQSTP-----TPGVAAAPTLVSGGGST 576
VP +L AP P+ A P E Q PP + P PG A G+
Sbjct: 662 GVPGDL---GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP 718
Query: 577 SSTSSGSFEASPVEPQLPSKEGPE--------------PPEE----VPPPTTPPVPKVEP 618
S + + P E GP+ P ++ + P PP P P
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778
Query: 619 KGDGIGPTRQP--PSQGLGYPKYQKSL----PPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
G P P+ G P + P F + +G A
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDA 838
Query: 673 -PPTPVPPSPPQPVTLGAVPAPQA------PPPPPKALYPGALGR-PPPMPPMNFDPRWM 724
PP P P+ P P +G V AP A PP +PGA GR PP P N P
Sbjct: 839 GPPGPAGPAGP-PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG- 896
Query: 725 MIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPP 784
PP P G PR + G E P E+G+P
Sbjct: 897 --PP----------------GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938
Query: 785 VDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPEN 844
D G TP P+ + +G R P +P P + PG +
Sbjct: 939 ADGPAGAPG-----TPG-PQGIAGQRGVVGLPGQRGERG-FPGLPGP----SGEPG--KQ 985
Query: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR 904
G G R P GP L PPG E + P + P ++ + G PA
Sbjct: 986 GPSGASGERGPPGPMGPPGLAGPPG--ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAG 1043
Query: 905 GVGS-GGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPI--KKPPPPTKV 961
G+ G G P P GP S RG P P GP+ + P P
Sbjct: 1044 PPGAPGAPGAPGP---------VGPAGKSGDRG--ETGPAGPAGPVGPVGARGPAGPQGP 1092
Query: 962 EELPPKPLEQGDETPKPPKP-DPLKITKGKLGGPKETPPNGNLSPA-PRLRRDYSYERVG 1019
+ EQGD K + L+ G G P E P+G PA PR G
Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR----------G 1142
Query: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP 1079
P G + G G G RGR GD G G G P PP P
Sbjct: 1143 PPGSAGAPGKDGLNGLPGPIGPPGPRGR-------------TGDAGPVGPPGPPG-PPGP 1188
Query: 1080 RGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESD---LAPSDKEAPTPKEGTLTQVP 1136
G S G ++ +P+ +++ + G D + D E T + Q+
Sbjct: 1189 PG-----PPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIE 1243
Query: 1137 LAPPPPGAPPSPA 1149
P G+ +PA
Sbjct: 1244 NIRSPEGSRKNPA 1256
Score = 88.2 bits (217), Expect = 8e-17
Identities = 289/1208 (23%), Positives = 358/1208 (29%), Gaps = 259/1208 (21%)
Query: 1109 GSETHESD---LAPSDKEAPTPKEGTLTQ----------------------VPLAPPPPG 1143
G+E E + + P E+PT +E T + +P P PG
Sbjct: 83 GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPG 142
Query: 1144 APPSPAPARFTARGGRVFTPR-------------GVPSRRGRGG--GRPPPQVCPG---- 1184
P P P GG F P+ VP G G G P P PG
Sbjct: 143 PPGPPGPPGPPGLGGN-FAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201
Query: 1185 WSPPAKSLAP-KKPPTGPLPPSKEPLK--------------EKLIPGPLSPVARG----- 1224
PP + P P GP P P K E+ PGP ARG
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQG--ARGLPGTA 259
Query: 1225 ---GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPA 1281
G G DG + G + P Q G G+P PA
Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319
Query: 1282 SAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP 1341
A G + A T P A P + E S+ RG+ P
Sbjct: 320 GARGNDGA--TGAAGPPGPTGPAGPPGFPGAVGAK-GEAGPQGPRGSEGPQGVRGEPGPP 376
Query: 1342 PPV-----LLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQN 1396
P P A G PG G PGI+ + PG +
Sbjct: 377 GPAGAAGPAGNPGADGQPGAKGANGAPGIAG------------------APGFPGARGPS 418
Query: 1397 RRPGPGGKAGSSGSSSGGGGGGPGGRTG----PGRGDKRSWPSPK----NRSRPPEERPP 1448
GPGG G G+S G G G TG PG + P P R E P
Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478
Query: 1449 GLPLPPPP---PSSSAVFRLDQVI----------HSNPAGIQQALAQLSSRQGSVTAPGG 1495
GLP PP P S D V PAG + + + + R G PG
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGE-AGRPGEAGLPGA 537
Query: 1496 H----------PRHKPGLPQAPQGPSPRP-PTRYEPQRVNSGLSSDPHFE----EPGPM- 1539
P K G P P G RP P R +G+ P + EPG
Sbjct: 538 KGLTGSPGSPGPDGKTG-PPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596
Query: 1540 VRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESR 1599
RGV G P + PP E P S P GP E+
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656
Query: 1600 DTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGD 1658
G + + + A R P + AG + G D GD
Sbjct: 657 KPGEQGVPGDL-----GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711
Query: 1659 SQVSSGPCSQRSSPDGGLKG--AAEGPPKRPGGSSPLNAVPCEGPPGSE-------PPRR 1709
+ P SQ + G+ G A G P G +G PG + P
Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGP 771
Query: 1710 PPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDS 1769
P PA GD+ E P GP G R DRG EPGP P+ GPP G
Sbjct: 772 PGPAGAPGDKGESGPSG--PAGPTGA-RGAPGDRG-EPGPPGPAGFAGPPGADGQ----- 822
Query: 1770 DLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSG 1829
K E + +A P P A A P + G P + G
Sbjct: 823 -------PGAKGEPGDAGAKGDAGP--------PGPAGPAGPPGPIGNVG----APGAKG 863
Query: 1830 QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPS 1889
R GSAGP P + GF + P PPGP P+
Sbjct: 864 AR-------GSAGP---------------PGATGFPGAAGRVGPPGPSGNAGPPGPPGPA 901
Query: 1890 ALLSGLALKGQFLDFSTMQATELGKL-------PAGGVLYPPPSFLYSPAFCPSP----- 1937
G +G+ T A G++ PAG P P P
Sbjct: 902 GKEGGKGPRGE-----TGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG 956
Query: 1938 ------LPDTSLLQVRQDLPSPSDFYST--------------PLQPGGQSG----FLPSG 1973
LP + LP PS P+ P G +G G
Sbjct: 957 QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG 1016
Query: 1974 APAQQMLLPMVDSQLPVVNFGSLPPAPPPAPP--PLSLLPVGPALQPPSLAVRPPPAPAT 2031
AP + S + G PA PP P P + PVGPA + P PA
Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076
Query: 2032 RVLP----SPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLN 2087
V P PA P + E + + ++ S G PG PP G
Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG----PPGSPGEQG-- 1130
Query: 2088 SRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRG 2147
PS SG + A D L +P P GP R G + PG G
Sbjct: 1131 ------PSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG 1184
Query: 2148 DKEPGLPP 2155
P PP
Sbjct: 1185 PPGPPGPP 1192
Score = 69.3 bits (168), Expect = 4e-11
Identities = 210/873 (24%), Positives = 259/873 (29%), Gaps = 195/873 (22%)
Query: 53 ARRMPPPANLPSLKAENKGND----PNVSLV--PKDGTGWASKQEQSDPKSSDASTAQPP 106
AR P P LP E G P V PK G + PK S +P
Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530
Query: 107 ESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFS 166
E+ LP ++ + P P + P P+G GA G G
Sbjct: 531 EAG-LPGAKG-LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG------- 581
Query: 167 REEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLH 226
FP + A + A ER GP+ + + G +GP GP +
Sbjct: 582 ---FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDG------EAGAQGPPGPAGPAGE-- 630
Query: 227 HGHDPRGGLQPSGPPQF--------PPYRGMMPPFM-YPPYLPFPPPYGPQGPYRYPTPD 277
RG P+G P F PP P P L P P G +G +P
Sbjct: 631 -----RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685
Query: 278 GPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTE 337
G P AGPRG+ G P D K D G GA
Sbjct: 686 GVQGPPGPAGPRGAN---------GAPG---NDGAK--------GDAGAPGAPGSQG-AP 724
Query: 338 KLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTA------ 391
L+ E G + G +G R G + P DG +G + PP P A
Sbjct: 725 GLQGMPGERGA-AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGE 783
Query: 392 ----------WAETSRPPETEPGPPAPKPPLPPPHR-GPAGNWGPPGDYPDRG--GP--- 435
A + EPGPP P PP G G G PGD +G GP
Sbjct: 784 SGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843
Query: 436 --PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRL 493
P PP P A + + S+ A
Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSA------------------------GPPGATGFPGA 879
Query: 494 DEKFGAPDKRLKAEPAAPPA--------APSTPAPPPAVPKELPAPPAPPPASAPTPETE 545
+ G P A P PP P P P E+ PP PP +
Sbjct: 880 AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV-GPPGPPGPAGEKGSPG 938
Query: 546 PEEPAQAPPAQSTPTP-GVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE--PP 602
+ PA AP TP P G+A +V G F P P K+GP
Sbjct: 939 ADGPAGAP---GTPGPQGIAGQRGVV---GLPGQRGERGFPGLPGPSGEPGKQGPSGASG 992
Query: 603 EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQH 662
E PP P P G+ G P ++ G P S + R +
Sbjct: 993 ERGPPGPMGPPGLAGPPGES-GREGAPGAE--GSPGRDGSPGAKGDRGETGPA------- 1042
Query: 663 QWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYP-GALGRPPPMPPM---- 717
AP P P P P P P + P GA G P P
Sbjct: 1043 -----GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKG 1097
Query: 718 -NFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAM 776
+ I + LQG P PPG P P S G P AP
Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPG----PPG-SPGEQGPSGASGPAGPRGPPGSAGAPGK 1152
Query: 777 LRERGTP-PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYL 835
G P P+ P P P +G + PV PP P
Sbjct: 1153 DGLNGLPGPIGP---------------PGP-------------RGRTGDAGPVGPPGP-- 1182
Query: 836 ASYPGFPENGAPGPPISRFPLEEPGPRPLPWPP 868
PG P G PGPP + F LP PP
Sbjct: 1183 ---PGPP--GPPGPPSAGFDFSF-----LPQPP 1205
Score = 40.0 bits (92), Expect = 0.025
Identities = 116/487 (23%), Positives = 149/487 (30%), Gaps = 111/487 (22%)
Query: 1687 PGGSSPLNAVPCEGPPGSEPPR--RPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRG 1744
PG P GPPG+ P+ + PP P PPGP G + D G
Sbjct: 178 PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPG----KNGDDG 233
Query: 1745 TEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPS 1804
P RP R GPP G L + L + +A P
Sbjct: 234 EAGKPGRPGER-GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP---------- 282
Query: 1805 AAASAEPQS--KNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSG 1862
A EP S +N G P G+R P G+ GP+ ++ + GA + P
Sbjct: 283 AGPKGEPGSPGENGAPGQMGPR-GLPGERGRP----GAPGPAGARGNDGATGAAGPPG-- 335
Query: 1863 GFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLY 1922
P GPA P + KG+ + Q + P G
Sbjct: 336 -------------------PTGPAGPPGFPGAVGAKGE----AGPQGPRGSEGPQGVRGE 372
Query: 1923 PPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLP 1982
P P P P P+ QPG + +GAP
Sbjct: 373 PGP---------PGPA----------GAAGPAGNPGADGQPGAKGA---NGAPGIAGAPG 410
Query: 1983 MVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPAL--------QPPSLAVRPPPAPATRVL 2034
++ P G P PP P S P P +P + V+ PP PA
Sbjct: 411 FPGARGPS---GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEG 467
Query: 2035 PSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATP 2094
AR P G L GP R P R F G + A P
Sbjct: 468 KRGARGEPGPTG---------------------LPGPPGERGGPGSRGFPGADG--VAGP 504
Query: 2095 STYSGVFRTQRVDLYQQASPPDALR----WIPKPWERTGPPPREGPSRRAEEPGSRG-DK 2149
+G R + SP +A R +P TG P GP + PG G D
Sbjct: 505 KGPAGE-RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563
Query: 2150 EPGLPPP 2156
PG P P
Sbjct: 564 RPGPPGP 570
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 146 bits (368), Expect = 2e-34
Identities = 408/1581 (25%), Positives = 511/1581 (32%), Gaps = 332/1581 (20%)
Query: 411 PLPPPHRGPAGNWGPPGDYPDRG--GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERAR 468
P P P P G G PG+ RG GPP P P Q S A +
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGS------ATAKGE 1297
Query: 469 RRREEEERRMQEERRAAC-----AEKLKR---LDEKFGAPDKRLKAEPAAPPAAPSTP-- 518
R + R RA A LK L G P +R P P AP
Sbjct: 1298 RGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIG 1357
Query: 519 APPPAVP--KELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGST 576
P +P K P P PP P + P P P G G
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKG---------DRGER 1408
Query: 577 SSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI----GPTRQPPSQ 632
G +P EP LP G P+ P PP K E KGD G QP S
Sbjct: 1409 GPPGPGEGGIAPGEPGLPGLPGSPGPQG---PVGPPGKKGE-KGDSEDGAPGLPGQPGSP 1464
Query: 633 GLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV--------------- 677
G P+ PP + ++ ++ ++G PP P
Sbjct: 1465 GEQGPRG----PPGAIGPKGDRGFPGPLGEAGEKGERG--PPGPAGSRGLPGVAGRPGAK 1518
Query: 678 -PPSPPQPVTLGAVPAPQAPPPPPKALYPGALG----------------------RPPPM 714
P PP P P P + P G R PP
Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578
Query: 715 PPMNFDPRWMMIPPYVDPRLLQGR--PPLDFYPPGVH--------PSGLVPRERSDSGGS 764
+ DP P P L GR PP D PPG P + PR R G
Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE 1638
Query: 765 SSE---PFDRHAPAMLRERG---TPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDD 818
+ P D P ERG P V + GD P E SP
Sbjct: 1639 KGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD--QGDPGEDGRNGSP----GSSGP 1692
Query: 819 KGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQT 878
KG R E P PP + + PG E G PG P G LP PG + +
Sbjct: 1693 KGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRG 1752
Query: 879 PP-PKKEPPKEETAQLTGPEAGRKPARGV-----GSGGQGPPPPRRESRTETRWGPRPGS 932
PP P+ +P + GP AG K RG SG G P S GP +
Sbjct: 1753 PPGPQGDP------GVRGP-AGEKGDRGPPGLDGRSGLDGKPGAAGPS------GPNGAA 1799
Query: 933 SRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLG 992
+ G P + G P R + P P+ LP KP E G KP L G+ G
Sbjct: 1800 GKAGDPGRD-GLPGLRGE--QGLPGPSGPPGLPGKPGEDG-------KPG-LNGKNGEPG 1848
Query: 993 GPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRG-----------RGEYFARGRGFRGT 1041
P E G + R+ R GP RG G G+GF G
Sbjct: 1849 DPGEDGRKGEKGDSGASGRE---GRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905
Query: 1042 YGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPP------------APRGRTASETRS 1089
GG G E S E +G G G G P P A R ET
Sbjct: 1906 PGGTGPKGDRGETGSKGE-QGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964
Query: 1090 EGS-EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPT--PKEGTLTQVPLAPPPPGAP- 1145
E S + +P+RRR ++G + P KE P P E L P P G P
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQ------GPPGKEGPIGFPGERGLKGDRGDPGPQGPPG 2018
Query: 1146 ------PSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGW----------SP 1187
P P+ G+ P G+P R G G GRP + G P
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIP-GLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077
Query: 1188 PAKSLAPKKP-PTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHG 1246
P P P P GP EP + G P G+ G + G + R G
Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEP--GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPG 2135
Query: 1247 RAQQQDKP-PRFR----RLKQERENAARGSEGKPSLTLPASAPG---------------- 1285
+ +P PR + L ER A G EGKP L P PG
Sbjct: 2136 IKGDRGEPGPRGQDGNPGLPGERGMA--GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193
Query: 1286 ---------------------PEEALTTVTVAPA----PRRAAAKSPDLSNQNSDQANEE 1320
P LT T A P + P S Q E
Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253
Query: 1321 WETASESSDFTSERRGDKEAPP-------PVLLTPKAVGTPGGGGGGAVPGISAM--SRG 1371
+ + D S + GD+ +P P + PK P G G AV G+ +G
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313
Query: 1372 DLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKR 1431
A DL PG + PGP G+ G +G + G PG PG ++
Sbjct: 2314 APGGLAGDL------VGEPGAKGDRGLPGPRGEKGEAGRA-----GEPG---DPGEDGQK 2359
Query: 1432 SWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVT 1491
P PK P PG P PP PP L + G+ Q R G +
Sbjct: 2360 GAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGL--PGAPGVVGFPGQTGPR-GEMG 2416
Query: 1492 APG-------GHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSD----------PHFE 1534
PG P + G+P P GP P PP P SGL D P E
Sbjct: 2417 QPGPSGERGLAGPPGREGIP-GPLGP-PGPPGSVGPPGA-SGLKGDKGDPGVGLPGPRGE 2473
Query: 1535 EPGPMVRGVGGTPRDSA--GVSPFPPKRRERPPR----KPELLQEES-----LPPPHSSG 1583
P +RG G P G++ P R ER + L ++ L PP G
Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRG 2533
Query: 1584 FLGSKPE-GP-------GPQAESRDTGTEALTPHIWNRLHTATS------RKSYRPSSME 1629
G E GP GP+ ++ D G + ++ +P +
Sbjct: 2534 AKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAG 2593
Query: 1630 PWMEPLSPFED-VAGTEMSQSDSGV----DLSGDSQVSSGPCSQRSSPDGGLKGAAEGPP 1684
+P SP +D V G + D G L G+ V G C + G KG A GPP
Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV-KGACG--LDGEKGDKGEA-GPP 2649
Query: 1685 KRPGGSSPLNAVPCEGPPG-SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDR 1743
RPG + + G PG S P + GDR + PGP G ++ ++ +R
Sbjct: 2650 GRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ-----PGPKG-DQGEKGER 2703
Query: 1744 GTE-----PGPIRPSHRPGPP 1759
GT PGP GPP
Sbjct: 2704 GTPGIGGFPGPSGNDGSAGPP 2724
Score = 140 bits (353), Expect = 1e-32
Identities = 403/1682 (23%), Positives = 533/1682 (31%), Gaps = 294/1682 (17%)
Query: 191 QSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMM 250
++ PGP P ++T + G G D G + + P G G P P RG
Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTP-GAPGLKGSPGLPGPRGD- 1336
Query: 251 PPFMYPPYLPFPPPYGPQGPYRYPTP-------DGPSRFPRVAGPRGSGPPMRLVEPVGR 303
P GP+GP P +GP R P SGPP P+G
Sbjct: 1337 -----------PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR-GPLGD 1384
Query: 304 PSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQS 363
P L G A ++ D E+ E G E G G S
Sbjct: 1385 PGPRGPPGLP-----------GTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433
Query: 364 ASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKP----PLPPPHRGP 419
G PP G+KG+S + P P + + P PG PK P P G
Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGE 1493
Query: 420 AGNWGPPGDYPDRGGP----------PCKPPAPED-EDEAWRQRRKQSSSEISLAVERAR 468
G GPPG RG P P PP P + E R + + AV A
Sbjct: 1494 KGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV--AG 1551
Query: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPA--APPAAPSTPAPP----P 522
+ E+ + R A + + D K +P P PP P
Sbjct: 1552 PKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP 1611
Query: 523 AVPKELPAPPAPP-PASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSS 581
K P P PP P + E E P PG A L G
Sbjct: 1612 PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGE 1671
Query: 582 GSFEASPVEP---QLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPK 638
+ P E P GP+ P P PP V+ G G +P +G P+
Sbjct: 1672 KGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD-TGPGAREKGEPGDRGQEGPR 1730
Query: 639 YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV-----PPSPPQPVTLGAVPAP 693
K P E+ ++ + Q G P PP L P
Sbjct: 1731 GPKG-DPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789
Query: 694 QAPPPP----PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP---- 745
P P KA PG G P +P P L G+P D P
Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQG-------LPGPSGPPGLPGKPGEDGKPGLNG 1842
Query: 746 ----PGVHPSGLVPRERSDSGGSSSEPFD-----RHAPAMLRERGTPPVDPKLAWVGDVF 796
PG E+ DSG S E D R AP +L +G P + + G F
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902
Query: 797 TATPAEPRPL-----TSPLRQAADEDDKGMRSETPPVPPPPPYL---------------- 835
P P T + ++G+R E VP L
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962
Query: 836 -----ASYPGFPE--------NGAPGPPISRFPLEEPGPRPL------PWPPGSDEVAKI 876
S+ PE +G GPP P+ PG R L P P G +A
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALG 2022
Query: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRG 936
+ PP P + P P R G G G P R E + G R R G
Sbjct: 2023 ERGPP---GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK---GERGEQGRDG 2076
Query: 937 IPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE 996
PP PG P GP P P V+E P P G++ P LK KG+ G +
Sbjct: 2077 -PPGLPGTP----GPPGPPGPKVSVDE--PGPGLSGEQ-----GPPGLKGAKGEPGSNGD 2124
Query: 997 TPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFR 1055
P G+ P ++ D RGE RG+ G G G RG +
Sbjct: 2125 QGPKGDRG-VPGIKGD---------------RGEPGPRGQDGNPGLPGERGMAGPEGK-P 2167
Query: 1056 SYREFRGDDGRGGGTGGPNHPPAP--RGRTASETRS--EGSEYEEIPKRRRQRGSETGSE 1111
+ RG G GG G P P AP G + S +G E P R G TG+
Sbjct: 2168 GLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTG-PTGAV 2226
Query: 1112 THESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRG 1171
PS P G QV G P +P + + G +P GVP G
Sbjct: 2227 GLPGPPGPSGLVGPQGSPGLPGQV----GETGKPGAPGRDGASGKDGDRGSP-GVPGSPG 2281
Query: 1172 RGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSN 1231
G P P + AP + G LP +K EK PG L+ G +
Sbjct: 2282 LPGPVGPK------GEPGPTGAPGQAVVG-LPGAK---GEKGAPGGLAGDLVGEPGAKGD 2331
Query: 1232 VGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPAS--APGPEEA 1289
G+ G R + GRA + P Q+ +G +G P + +P S PGP
Sbjct: 2332 RGL-PGPRGEKGEAGRAGEPGDPGED---GQKGAPGPKGFKGDPGVGVPGSPGPPGPPGV 2387
Query: 1290 LTTVTVAPAPRRAAAKS-PDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTP 1348
+ + P P + + S RG PP P
Sbjct: 2388 KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPG----------PSGERG-LAGPPGREGIP 2436
Query: 1349 KAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSS 1408
+G PG G PG S + +GD L PG+ ++ RPG G G +
Sbjct: 2437 GPLGPPGPPGSVGPPGASGL-KGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLT 2495
Query: 1409 GSSSGGGGGGPGGRTGPG--RGDKRSW------PSPKNRSRPPEER-PPGLPLPPPPPSS 1459
G G G G G +GDK P P+ ER P GL P
Sbjct: 2496 GPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGD 2555
Query: 1460 SAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLP--QAPQGPSPRPPTR 1517
+ +P +GS PG + GLP + GP +P
Sbjct: 2556 ----------NGDPGD-----------KGSKGEPG--DKGSAGLPGLRGLLGPQGQPGA- 2591
Query: 1518 YEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPK--RRERPPRKPELLQEES 1575
+G+ DP P GV G + V P+ + ER +
Sbjct: 2592 -------AGIPGDP----GSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVK--------- 2631
Query: 1576 LPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPL 1635
+ G G K G + E+ G L H + EP +
Sbjct: 2632 ----GACGLDGEK----GDKGEAGPPGRPGLAGH--------------KGEMGEPGVPGQ 2669
Query: 1636 SPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNA 1695
S G + D G D + G +R +P G+ G GP G + P
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTP--GI-GGFPGPSGNDGSAGP--- 2723
Query: 1696 VPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHR 1755
GPPGS PR P + P E+ + + +R ++G PGP P
Sbjct: 2724 ---PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQG-RPGPAGPRGE 2779
Query: 1756 PG 1757
G
Sbjct: 2780 KG 2781
Score = 128 bits (322), Expect = 5e-29
Identities = 394/1580 (24%), Positives = 507/1580 (32%), Gaps = 295/1580 (18%)
Query: 59 PANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPA----- 113
P LP + D P G G + E P + Q P P
Sbjct: 1390 PPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGD 1449
Query: 114 SQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTL 173
S+ A P +P + E P P G G GD G L + E
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAI---------GPKGDRGFPGPLGEAGEKGERGPP 1500
Query: 174 QAAGDQD-KAAKERESAEQSSGP-GPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDP 231
AG + R A+ GP GP+ R + G G + GP G
Sbjct: 1501 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG---EPGRPGDPAVVGPAVAGPKGE-- 1555
Query: 232 RGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRG- 290
+G + P+GP +G P P L P GP+G P GP AGP G
Sbjct: 1556 KGDVGPAGPRGATGVQGERGP----PGLVLPGDPGPKGD---PGDRGPIGLTGRAGPPGD 1608
Query: 291 SGPPMRLVEPVGRPSILKEDNLKEFD-QLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRD 349
SGPP +P GRP + D ++ ++ D+G G L E G
Sbjct: 1609 SGPPGEKGDP-GRPGPPGPVGPRGRDGEVGEKGDEGPPG-------DPGLPGKAGERGL- 1659
Query: 350 SDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE----------PPTPKTAWAETSRPP 399
GA G R G++ P DG+ G SP S PP P +T P
Sbjct: 1660 ---RGAPGVRGPVGEKGDQGDPGEDGRNG-SPGSSGPKGDRGEPGPPGPPGRLVDTG-PG 1714
Query: 400 ETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCK-PPAPEDEDEAWRQRRKQSSS 458
E G P + P RGP G+ G PG +RG + PP P+ +
Sbjct: 1715 AREKGEPGDRGQEGP--RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGV---------- 1762
Query: 459 EISLAVERARRRREEEERRMQEERRAACAEKLKR----LDEKFGAPDKRLKAEPAAPPAA 514
R EK R LD + G K A P+ P A
Sbjct: 1763 ------------------------RGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGA 1798
Query: 515 PSTPAPP-----PAVPKE--LPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAP 567
P P + E LP P PP +P E + PG
Sbjct: 1799 AGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG-----KPGEDGKPGLNGKNGEPGDPGED 1853
Query: 568 TLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPP------VPK-VEPKG 620
G + ++ + E P GP+ P +P P PP VP PKG
Sbjct: 1854 GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG 1913
Query: 621 DGIGPTRQPPSQGLGYPKYQKSLP---PRFQRQQQEQLLKQQQQHQ----WQQHQQGSAP 673
D G T QGL + + P P R + +K + W + GS
Sbjct: 1914 DR-GETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE-SSGSFL 1971
Query: 674 PTPVPPSPPQPVTLGAVPAPQAPPP--PPKALYPGALGRPPPMPPMNFDPRWMMIPPYVD 731
P P P+ + P + P P + G G P P P
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP--------------- 2016
Query: 732 PRLLQGRPPLDFYPPGVHPSGLVPRE----------RSDSGGSSSEPFDRHAPAMLRERG 781
P L G PPG PSGL R+ G + P +R ERG
Sbjct: 2017 PGLALGERG----PPG--PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERG 2070
Query: 782 TPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGF 841
D G TP P P P + + DE G+ E P P L G
Sbjct: 2071 EQGRDGPPGLPG-----TPGPPGP-PGP-KVSVDEPGPGLSGEQGP-----PGLKGAKGE 2118
Query: 842 P-ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGR 900
P NG GP R G R P P G D + P + E L GP
Sbjct: 2119 PGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGL--PGERGMAGPEGKPGLQGPRGPP 2176
Query: 901 KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRA--GP-----IK 953
P GG G P P GP+ S +G P E PP R GP +
Sbjct: 2177 GPV-----GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGET--GPPGRGLTGPTGAVGLP 2229
Query: 954 KPPPPTKV---EELPPKPLEQGDETPKPPKP--DPLKITKGKLG--------------GP 994
PP P+ + + P P + G ET KP P D G G GP
Sbjct: 2230 GPPGPSGLVGPQGSPGLPGQVG-ETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288
Query: 995 KETP-PNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARG-RGFRGTYGGRGRGARSR 1052
K P P G A E+ P G GE A+G RG G G +G R+
Sbjct: 2289 KGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAG 2348
Query: 1053 EFRSYRE-----------FRGDDGRG-GGTGGPNHPPAPRGRTASETRSEGSEYEEIPKR 1100
E E F+GD G G G+ GP PP +G P +
Sbjct: 2349 EPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQ 2408
Query: 1101 RRQRGSETGSE--THESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGG 1158
RG E G + E LA P +EG +P PPG P S P + G
Sbjct: 2409 TGPRG-EMGQPGPSGERGLA-----GPPGREG----IPGPLGPPGPPGSVGPPGASGLKG 2458
Query: 1159 RVFTPR-GVPSRRGRGG--------GRPPPQVCPGWSPPAKSLAPK--KPPTGPLPPSKE 1207
P G+P RG G GRP + G + P S + K G +
Sbjct: 2459 DKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518
Query: 1208 PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENA 1267
+I GP P G G DG++ R +G + + E
Sbjct: 2519 KGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGS---------KGEPG 2569
Query: 1268 ARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA-----NEEWE 1322
+GS G P L G A +P + P + + D + E
Sbjct: 2570 DKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGV--PGIRGEKGDVGFMGPRGLKGE 2627
Query: 1323 TASESSDFTSERRGDK-EAPPPVLLTPKAVGTPGGGGGGAVPGIS-AMSRGDLSQRAKDL 1380
+ + +GDK EA PP P G G G VPG S A + L D
Sbjct: 2628 RGVKGACGLDGEKGDKGEAGPPG--RPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGD- 2684
Query: 1381 SKRSFSSQR-----PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPS 1435
R F Q G + + PG GG G SG+ G GP G GP RG +
Sbjct: 2685 --RGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP-RGPE-GLQG 2740
Query: 1436 PKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAG------------------IQ 1477
K PP ER G P P P + PAG ++
Sbjct: 2741 QKGERGPPGERVVGAPGVPGAPGERG-----EQGRPGPAGPRGEKGEAALTEDDIRGFVR 2795
Query: 1478 QALAQLSSRQGSVTAPGGHP 1497
Q ++Q + QG A G P
Sbjct: 2796 QEMSQHCACQGQFIASGSRP 2815
Score = 121 bits (304), Expect = 6e-27
Identities = 310/1264 (24%), Positives = 388/1264 (30%), Gaps = 266/1264 (21%)
Query: 796 FTATPA-EPRPLTSPLRQAADEDDKGMRSET-PPVPPPPPYLASYPG------------- 840
FT P EP P+ P Q + + G+R + PP P P PG
Sbjct: 1238 FTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGE 1297
Query: 841 --FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP--PKEETA---QL 893
FP GA G P S PG P GS + + P ++ P PK E Q+
Sbjct: 1298 RGFP--GADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV 1355
Query: 894 TGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPR-------------------PGSSR 934
G E P R G GPP PR GP PG
Sbjct: 1356 IGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE 1415
Query: 935 RGIPPEEPGAP--PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLG 992
GI P EPG P P GP PP K E +GD P G+ G
Sbjct: 1416 GGIAPGEPGLPGLPGSPGPQGPVGPPGKKGE-------KGDSEDGAPG------LPGQPG 1462
Query: 993 GPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSR 1052
P E P G +GP RG A +G RG G G
Sbjct: 1463 SPGEQGPRGPPGA------------IGPKGDRGFPGPLGEAGEKGERGPPGPAGS----- 1505
Query: 1053 EFRSYREFRGDDGRGGGTGGPNHPPAPRGRTAS--ETRSEGSEYEEIPKRRRQRGSETGS 1110
R G GR G G P PP P GR E G P + G
Sbjct: 1506 -----RGLPGVAGRPGAKG-PEGPPGPTGRQGEKGEPGRPGDPAVVGP-------AVAGP 1552
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQ----VPLAPPPPGAPPSPAPARFTARGGRVFTPRGV 1166
+ + D+ P+ T +G +P P P G P P T R G G
Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPP-GDSGP 1611
Query: 1167 PSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKE-------------PLKE 1211
P +G G G P P G + PP P P K P+ E
Sbjct: 1612 PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGE 1671
Query: 1212 KLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER-ENAARG 1270
K G R GS G S + GE GR R + +R + RG
Sbjct: 1672 KGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG 1731
Query: 1271 SEGKPSLTLPASAPGPEEALTTVTVAPAPRR-AAAKSPDLSNQNSDQANEEWETASESSD 1329
+G P L APG E + P P+ + P A E+ + D
Sbjct: 1732 PKGDPGLP---GAPG-ERGIEGFRGPPGPQGDPGVRGP---------AGEKGDRGPPGLD 1778
Query: 1330 FTSERRGDKEAPPPVLLTPK-AVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQ 1388
S G A P P A G G G +PG+ L +
Sbjct: 1779 GRSGLDGKPGAAGPS--GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836
Query: 1389 RPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPP 1448
+PG+ +N PG G+ G G G G GR GP +G+ R P + PP
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGP-KGE-RGAPGILG-----PQGPP 1889
Query: 1449 GLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--LSSRQGSVTAPGGHPRHKPGLPQA 1506
GLP P PP G + + L +G PG P L A
Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETA 1949
Query: 1507 ----------------PQGPSPRPPTRYEPQRVNSGLSSDPHFEEP--GPMVRGVGGTPR 1548
G P R + +SG P E P P RG+ G
Sbjct: 1950 GIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRG 2009
Query: 1549 DSAGVSPFPPKRRERPPRKPELLQEESLPP--PHSSGFLGSKPEG--PGPQAESRDTGTE 1604
D P ER P P L E P P G G E PG + E + G
Sbjct: 2010 DPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGER 2069
Query: 1605 ALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGD------ 1658
+ P + P P G ++S + G LSG+
Sbjct: 2070 G-------------EQGRDGPPGLPGTPGPPGP----PGPKVSVDEPGPGLSGEQGPPGL 2112
Query: 1659 --------SQVSSGPCSQRSSPDGGLKGAAEGPPKR-----PGGSSPLNAVPCEGPPGSE 1705
S GP R P G+KG P R PG EG PG +
Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGVP--GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170
Query: 1706 PPRRPP-PAPHDGD--------------------RKELPREQ----------------PL 1728
PR PP P GD K P E P
Sbjct: 2171 GPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPG 2230
Query: 1729 PPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTAS 1788
PPGP G Q + PG + + +PG P + G S KD D + + S
Sbjct: 2231 PPGPSGLVGPQGSP--GLPGQVGETGKPGAPGRDGASGKDGD---------RGSPGVPGS 2279
Query: 1789 VTEAIPVSRDWELLPSAA----------ASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFY 1838
PV E P+ A A E + +G V EP + G R
Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR------- 2332
Query: 1839 GSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQP-LYLP--PGPAPPSALLSGL 1895
G GP + G P G + G P ++ P + +P PGP P + L
Sbjct: 2333 GLPGPRGEKGEAGRAGEPGDPGEDG-QKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDL 2391
Query: 1896 ALKG 1899
L G
Sbjct: 2392 GLPG 2395
Score = 90.5 bits (223), Expect = 2e-17
Identities = 217/847 (25%), Positives = 278/847 (32%), Gaps = 211/847 (24%)
Query: 971 QGDETPKP-PKPDPLKITKGKLGGPKETPPNGNLSPA--PRLRRDYSYERVGPTSCRGRG 1027
Q T +P P+P P+ KG+ G P E G + P P L G T G
Sbjct: 1235 QASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGL--------PGRTGAPGPQ 1286
Query: 1028 RGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHP--------PAP 1079
A +G RG G GR G GR G G P P P P
Sbjct: 1287 GPPGSATAKGERGFPGADGR-------------PGSPGRAGNPGTPGAPGLKGSPGLPGP 1333
Query: 1080 RGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAP 1139
RG E G + E + G G + D PS P + PL
Sbjct: 1334 RG-DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGP--------RGPLGD 1384
Query: 1140 PPPGAPPS-PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP 1198
P P PP P A +G R RG P G GG + PG P L P
Sbjct: 1385 PGPRGPPGLPGTAMKGDKGDR--GERGPPG-PGEGG------IAPG-EPGLPGLPGSPGP 1434
Query: 1199 TGPL-PPSKEPLK---EKLIPG----PLSPVARG-----------GSNGGSNVGMEDGER 1239
GP+ PP K+ K E PG P SP +G G G E GE+
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEK 1494
Query: 1240 PRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAP 1299
R G A + P G G+P P PGP P
Sbjct: 1495 GERGPPGPAGSRGLP---------------GVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539
Query: 1300 RRAAAKSPDLSNQNSDQANEEWETASESSDFTSER-------------RGDKEAPPPVLL 1346
A P ++ ++ + ++ ER +GD P+ L
Sbjct: 1540 GDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGL 1599
Query: 1347 TPKA-----VGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGP 1401
T +A G PG G PG G + R +D + P + PG
Sbjct: 1600 TGRAGPPGDSGPPGEKGDPGRPG----PPGPVGPRGRDGEVGEKGDEGPPGD-----PGL 1650
Query: 1402 GGKAGSSGSSSGGGGGGPGGRTG----PGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPP 1457
GKAG G G GP G G PG + P S P +R G P PP PP
Sbjct: 1651 PGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSP---GSSGPKGDR--GEPGPPGPP 1705
Query: 1458 SSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQA----------- 1506
+++ + P ++ ++G P G P+ PGLP A
Sbjct: 1706 G--------RLVDTGPGAREKGEPGDRGQEG----PRG-PKGDPGLPGAPGERGIEGFRG 1752
Query: 1507 ---PQG-PSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRE 1562
PQG P R P + R GL + P G G P +AG + P +
Sbjct: 1753 PPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGK-PGAAGPSG-PNGAAGKAGDPGR--- 1807
Query: 1563 RPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKS 1622
P L E+ LP P L KP G + G
Sbjct: 1808 --DGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG-------------------- 1845
Query: 1623 YRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEG 1682
EP P ED G + + DSG + + GP +R +P G+ G +G
Sbjct: 1846 ----------EPGDPGED--GRKGEKGDSG---ASGREGRDGPKGERGAP--GILG-PQG 1887
Query: 1683 PPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKEL--PREQPLPPGPIGTERSQR 1740
PP PG P+ GPPG P P GDR E EQ LP ER R
Sbjct: 1888 PPGLPG---PV------GPPGQGFPGVPGGTGPKGDRGETGSKGEQGLP-----GERGLR 1933
Query: 1741 TDRGTEP 1747
+ G+ P
Sbjct: 1934 GEPGSVP 1940
Score = 69.3 bits (168), Expect = 4e-11
Identities = 126/512 (24%), Positives = 159/512 (31%), Gaps = 76/512 (14%)
Query: 1270 GSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSD 1329
G G L APG + T V P + DQA TA +
Sbjct: 1191 GMAGADPEQLRRLAPGMDSVQTFFAVDDGP-------------SLDQAVSGLATALCQAS 1237
Query: 1330 FTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQR 1389
FT++ R + P PV G PG G RG +
Sbjct: 1238 FTTQPRPE---PCPVYCPKGQKGEPGEMG----------LRGQVGPPGD----------- 1273
Query: 1390 PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEERPP 1448
PG+ + PGP G GS+ + G G GR G PGR +P P + P
Sbjct: 1274 PGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG-----NPGTPGAPGLKGSP 1328
Query: 1449 GLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQ 1508
GLP P P P G A Q+ +G PG P P P+
Sbjct: 1329 GLPGPRGDPGERG--------PRGPKGEPGAPGQVIGGEGP-GLPGRKGDPGPSGPPGPR 1379
Query: 1509 GPSPRPPTRYEPQRVNSGLSSDPHFE-EPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRK 1567
GP P R P + + D E GP G GG G+ P + P
Sbjct: 1380 GPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVG 1439
Query: 1568 PELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSS 1627
P + E + L +P PG Q G A+ P +
Sbjct: 1440 PPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG--AIGPKGDRGFPGPLGEAGEKGER 1497
Query: 1628 MEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK-- 1685
P VAG ++ G Q G + P + G A PK
Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP--AVVGPAVAGPKGE 1555
Query: 1686 ----RPGGSSPLNAVPCE-GPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG-TERSQ 1739
P G V E GPPG P P P GDR GPIG T R+
Sbjct: 1556 KGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR-----------GPIGLTGRAG 1604
Query: 1740 RTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDL 1771
PG RPGPP G +D ++
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEV 1636
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 143 bits (360), Expect = 2e-33
Identities = 324/1315 (24%), Positives = 413/1315 (31%), Gaps = 232/1315 (17%)
Query: 509 AAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEP--------EEPAQAPPAQS--- 557
A+ P P K++ P PP P E P E+ A P +
Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155
Query: 558 -TP----TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPP 612
TP PG P GG+ ++ +G F+ QL +GP P P PP
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG---PRGPP 212
Query: 613 VPKVEPKGDGI-GPTRQPPSQGLGYPKYQKSLP--PRFQRQQQEQLLKQQQQHQWQQHQQ 669
P P G G +P G+ P + P P E + + Q
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272
Query: 670 GSA--PPTPVPPSPP----QPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRW 723
G+ P TP P P GA AP ++ PG G P PM P
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE- 331
Query: 724 MMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERG-T 782
P G D P P G V G + P AP E G T
Sbjct: 332 ---RGRTGPAGAAGARGNDGQPGPAGPPGPV--------GPAGGPGFPGAPGAKGEAGPT 380
Query: 783 PPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP 842
P+ A TP P P + D S P +A PGFP
Sbjct: 381 GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG------IAGAPGFP 434
Query: 843 -ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRK 901
G PGP + PL GP+ PG Q P + P + A E G++
Sbjct: 435 GPRGPPGPQGATGPL---GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491
Query: 902 PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPP---P 958
ARG GG GP P G R RG P ++ A P+ A + P P
Sbjct: 492 GARGE-PGGVGPIGPP---------GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541
Query: 959 TKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERV 1018
P +P E G L +G G P + P G + P+ D
Sbjct: 542 KGANGDPGRPGEPG-----------LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP 590
Query: 1019 GPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSRE--FRSYREFRGDDGRGGGTG--GPN 1074
GP RG+ GF G G G ++ E RG G+ G TG GP
Sbjct: 591 GPQGARGQ------PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644
Query: 1075 HPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQ 1134
P P G + S ++ +P G E G P D+ P
Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPG-EGGK--------PGDQGVPGEA------ 689
Query: 1135 VPLAPPPPGAPPSPAPARFTARGGRVFT-PRGVPSRRGRGGGRPPPQVCPGWSPPAKSLA 1193
GAP P RG R F RG P +G G R P PG P +
Sbjct: 690 --------GAPGLVGP-----RGERGFPGERGSPGAQGLQGPRGLPGT-PGTDGPKGASG 735
Query: 1194 PKKPPTGPLPPSKEPLKEKL----IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
P PP PP + + + I GP G G +DG R G
Sbjct: 736 PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG--- 792
Query: 1250 QQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDL 1309
PP N +G G P PA + G A P A P
Sbjct: 793 ----PPG-----PAGANGEKGEVGPPG---PAGSAGARGAPGERGETGPPGPAGFAGPPG 840
Query: 1310 SNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMS 1369
++ E+ E ++GD AP P G PG G V G
Sbjct: 841 ADGQPGAKGEQGEAG---------QKGDAGAPGP----QGPSGAPGPQGPTGVTGPKGAR 887
Query: 1370 RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGD 1429
A + PG PGP G +G G G GP GR G
Sbjct: 888 GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947
Query: 1430 KRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGS 1489
+ P P + P ++ P G PP P L+ ++G
Sbjct: 948 GPAGP-PGEKGEPGDDGPSGAEGPPGPQG------------------------LAGQRGI 982
Query: 1490 VTAPGGH-PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM----VRGVG 1544
V PG R PGLP GPS P + P G S D PGP+ + G
Sbjct: 983 VGLPGQRGERGFPGLP----GPSGEPGKQGAP-----GASGDRG--PPGPVGPPGLTGPA 1031
Query: 1545 GTP-RDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSK-PEGP-GPQAESRDT 1601
G P R+ + + PP R K + + ++ P + G GS P GP G Q + +
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1091
Query: 1602 GTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQV 1661
G + P+ P AG Q G GD
Sbjct: 1092 GAQG----------------------------PMGP-SGPAGARGIQGPQGP--RGDKGE 1120
Query: 1662 SSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKE 1721
+ P + G G +G P PG S A GP G PR PP P K+
Sbjct: 1121 AGEPGERGLKGHRGFTGL-QGLPGPPGPSGDQGA---SGPAGPSGPRGPP-GPVGPSGKD 1175
Query: 1722 LPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVG 1776
P P GP G R E GP P PGPP G D+ G
Sbjct: 1176 GANGIPGPIGPPGPR-----GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAG 1225
Score = 126 bits (316), Expect = 3e-28
Identities = 305/1226 (24%), Positives = 385/1226 (31%), Gaps = 264/1226 (21%)
Query: 352 EEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP----------------------K 389
E+G G R + G P DG+ G N PP P +
Sbjct: 130 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 189
Query: 390 TAWAETSRPPETEPGPPAPK-PPLPPPHRGPAGNWGPPGDYPDRG--------GPPCKPP 440
A + GP P+ PP P GP G G PG+ + G GPP P
Sbjct: 190 KAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 249
Query: 441 APEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAP 500
P D+ EA + + + + AR + R L + GAP
Sbjct: 250 KPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGHRGYPG--LDGAKGEAGAP 305
Query: 501 DKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP-PASAPTPETEPEEPAQA-PPAQST 558
+K E +P S P P P+ LP PA A +P A PP
Sbjct: 306 G--VKGESGSPGENGS---PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 360
Query: 559 PT--PGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKV 616
P PG AP G T + + EP P GP P P K
Sbjct: 361 PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKG 420
Query: 617 EPKGDGI-------GPTRQPPSQGLGYPKYQKSL--PPRFQRQQQEQLLKQQQQHQWQQH 667
GI GP P QG P K P + EQ K + Q
Sbjct: 421 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG 480
Query: 668 QQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPM------------- 714
G A + +P +G + P P +PG G P
Sbjct: 481 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 540
Query: 715 -PPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG-VHPSGLVPRERSDSGGSSSEPFDRH 772
N DP P R L GRP D P G V PSG P E G
Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPG-DAGPQGKVGPSG-APGEDGRPG---------- 588
Query: 773 APAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPP 832
P RG P V + + G EP +KG+ P
Sbjct: 589 PPGPQGARGQPGV---MGFPGP--KGANGEP----------GKAGEKGL--------PGA 625
Query: 833 PYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEE-- 889
P L PG E GA GPP P E G + P P G + PP + P ++
Sbjct: 626 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 685
Query: 890 -----TAQLTGPEAGRK-PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPG 943
L GP R P G QG PR T GP+ S P
Sbjct: 686 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG--------PA 737
Query: 944 APPRRAGP--IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNG 1001
PP GP ++ P + ++GD K P+ P GK GG T P G
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP-----GKDGGRGLTGPIG 792
Query: 1002 NLSPAPRLRRDYSYERVGPTSCRG-RG----RGEYFARG-RGFRGTYGGRGR-GARSREF 1054
PA GP G RG RGE G GF G G G+ GA+ +
Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852
Query: 1055 RSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIP---------KRRRQRG 1105
+ + +GD G G GP+ P P+G T T +G+ + P R
Sbjct: 853 EAGQ--KGDAG-APGPQGPSGAPGPQGPT-GVTGPKGARGAQGPPGATGFPGAAGRVGPP 908
Query: 1106 SETGSETHESDLAPSDKEAPTPKEGTL----------TQVPLAPP----------PPGAP 1145
G+ PS K+ P G Q P PP P GA
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 968
Query: 1146 PSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLP 1203
P P + G V G+P +RG G G P P PG A + + P GP+
Sbjct: 969 GPPGPQGLAGQRGIV----GLPGQRGERGFPGLPGPSGEPG-KQGAPGASGDRGPPGPVG 1023
Query: 1204 PSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQE 1263
P + GP R GS G D PP
Sbjct: 1024 PPG-------LTGPAGEPGREGSPGA----------------------DGPP-------G 1047
Query: 1264 RENAA--RGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
R+ AA +G G+ APGP +P P K D
Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPG-------SPGPAGPTGKQGD------------- 1087
Query: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLS 1381
RG+ A P +G G G + G RGD + A +
Sbjct: 1088 -------------RGEAGAQGP-------MGPSGPAGARGIQGPQG-PRGDKGE-AGEPG 1125
Query: 1382 KRSFSSQR--PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSW------ 1433
+R R G++ PGP G G+SG + G GP G GP D +
Sbjct: 1126 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1185
Query: 1434 -PSPKNRS-RPPEERPPGLPLPPPPP 1457
P P+ RS PPG P PP PP
Sbjct: 1186 PPGPRGRSGETGPAGPPGNPGPPGPP 1211
Score = 118 bits (296), Expect = 5e-26
Identities = 308/1205 (25%), Positives = 391/1205 (32%), Gaps = 200/1205 (16%)
Query: 130 ENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESA 189
E P+ P+ + A AS G G G + + P Q + +R
Sbjct: 84 ECCPICPTDL---ATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140
Query: 190 EQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPD-------SKLHHGHDPR-GGLQ----- 236
+ PGP R T + G GP GP +++ G D + GG Q
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200
Query: 237 -PSGP--PQFPPYRGMMPP---FMYPPYLPFPP-------PYGPQGPYRYPTPDGPSRFP 283
P GP P+ PP P F P P P P GP GP P DG + P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260
Query: 284 RVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDD-------GWAGAHEEVDYT 336
AG RG P G P + + + LD + G +G+ E
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320
Query: 337 EKL--KFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAE 394
+ + E GR + GA G R + G PP G G P K
Sbjct: 321 GPMGPRGLPGERGR-TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379
Query: 395 T-SRPPETEPG----PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGP----------PCKP 439
T +R PE G P P P P G G G PG G P P P
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439
Query: 440 PAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGA 499
P P+ K + E +A + + + E + A + + K GA
Sbjct: 440 PGPQGATGPLGP--KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE----EGKRGA 493
Query: 500 PDKRLKAEPAAPP---AAPSTPAPPP----AVPKELPAPPAPPPASAPT-PETEPEEPAQ 551
+ P PP AP P A PK P P + P +P P +
Sbjct: 494 RGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE 553
Query: 552 APPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP 611
PG+ A L G +P E P GP+ P
Sbjct: 554 ---------PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604
Query: 612 PVPKVEPKGDG-IGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQG 670
P PK G G P + GL + LP + + G
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGL------RGLPGK-------------------DGETG 639
Query: 671 SA-PPTPVPPS-------PPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPR 722
+A PP P P+ P P +P P P PP + PG G P
Sbjct: 640 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGP--PGPPGEGGKPGDQGVPGEAG------- 690
Query: 723 WMMIPPYVDPRLLQGRPPLDFYPPGVH----PSGLVPRERSD----SGGSSSEPFDRHAP 774
P V PR +G P + PG P GL +D + G + P + P
Sbjct: 691 ---APGLVGPRGERGFPG-ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746
Query: 775 ---AMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPP 831
M ERG + GDV E P +P + G R T P+ PP
Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDV-----GEKGPEGAPGKD-------GGRGLTGPIGPP 794
Query: 832 PPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETA 891
P A+ E G PGP S PG R PPG A PP P +
Sbjct: 795 GPAGANGEK-GEVGPPGPAGSAGARGAPGERGETGPPGP---AGFAGPPGADGQPGAKGE 850
Query: 892 QLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGP 951
Q EAG+K G G QGP GP+ +G PP G P AG
Sbjct: 851 Q---GEAGQKGDAG-APGPQGPSGAPGPQGPTGVTGPKGARGAQG-PPGATGF-PGAAGR 904
Query: 952 IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
+ PP + PP P P P D K +G G P G PA
Sbjct: 905 V--GPPGSNGNPGPPGP-------PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE 955
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG 1071
GP+ G + A RG G G RG R F G+ G+ G G
Sbjct: 956 KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG----ERGFPGLPGPSGEPGKQGAPG 1011
Query: 1072 -----GPNHPPAPRGRT--ASETRSEGSEYEEIPKRR------RQRGSETGSETHESDLA 1118
GP P P G T A E EGS + P R + ETG+
Sbjct: 1012 ASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071
Query: 1119 PSDK---EAPTPKEGTL----TQVPLAPP-PPGAPPSPAPARFTARGGRVFTP--RGVPS 1168
P PT K+G Q P+ P P GA P G P RG+
Sbjct: 1072 PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG 1131
Query: 1169 RRGRGG-----GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVAR 1223
RG G G P P G S PA P+ PP GP+ PS + IPGP+ P
Sbjct: 1132 HRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP-GPVGPSGKD-GANGIPGPIGPPGP 1189
Query: 1224 GGSNG 1228
G +G
Sbjct: 1190 RGRSG 1194
Score = 95.9 bits (237), Expect = 4e-19
Identities = 294/1251 (23%), Positives = 380/1251 (30%), Gaps = 301/1251 (24%)
Query: 1036 RGFRGTYGGRGR-GARSREFRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASETRSEGS 1092
RG RG G +G G R R+ G+ G G G GP PP P G +
Sbjct: 134 RGDRGDKGEKGAPGPRGRD--------GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAG 185
Query: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA--- 1149
++E + G++ G + Q P+ P P PP PA
Sbjct: 186 GFDE-----KAGGAQLG----------------------VMQGPMGPMGPRGPPGPAGAP 218
Query: 1150 -PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEP 1208
P F G G P G G R PP P P A K G P P
Sbjct: 219 GPQGFQGNPGEP----GEPGVSGPMGPRGPPG--PPGKPGDDGEAGKPGKAGERGPPG-P 271
Query: 1209 LKEKLIPG-PLSPVARG-----------GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPR 1256
+ PG P P +G G G V E G G + P
Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331
Query: 1257 FRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQ 1316
R ARG++G+P PA PGP V PA +P
Sbjct: 332 RGRTGPAGAAGARGNDGQPG---PAGPPGP--------VGPAGGPGFPGAPGAKG----- 375
Query: 1317 ANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQR 1376
E T + + RG+ P G+PG G PG + S
Sbjct: 376 --EAGPTGARGPEGAQGPRGEPGTP----------GSPGPAGASGNPGTDGIPGAKGSAG 423
Query: 1377 AKDLSKR-SFSSQR--PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSW 1433
A ++ F R PG + GP G+ G G + G GP G GP
Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 483
Query: 1434 PSPKNRSRPPEERPPGL-PLPPP----PPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQG 1488
P+ + R P G+ P+ PP P + D + A ++ + L+ +G
Sbjct: 484 PAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543
Query: 1489 SVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVN-SGL-SSDPHFEEPGPMVRGVGGT 1546
+ PG +PGLP A +G + RP +V SG D PGP +G G
Sbjct: 544 ANGDPGRPG--EPGLPGA-RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP--QGARGQ 598
Query: 1547 PRDSAGVSPFP-PKRRERPPRKPELLQEESLPP-------PHSSGFLGSK-PEGP-GPQA 1596
P GV FP PK P K E+ LP P G G+ P GP GP
Sbjct: 599 P----GVMGFPGPKGANGEPGKAG---EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651
Query: 1597 ESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLS 1656
E + G PS + P P G D GV
Sbjct: 652 ERGEQGAPG-------------------PSGFQGLPGPPGP----PGEGGKPGDQGVPGE 688
Query: 1657 GDSQVSSGPCSQRSSP-DGGLKGAA--EGP---PKRPGGSSPLNAVPCEGPPGSEPPRRP 1710
+ GP +R P + G GA +GP P PG P A GPPG++ P
Sbjct: 689 AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 748
Query: 1711 PPAPHD----------GDRKELPREQPL----------------PPGPIGTERSQRTDRG 1744
P + GDR ++ + P PPGP G
Sbjct: 749 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA--------N 800
Query: 1745 TEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPS 1804
E G + P PGP G + + E A P D + P
Sbjct: 801 GEKGEVGP---PGPAGSAGARGAPGE---------RGETGPPGPAGFAGPPGADGQ--PG 846
Query: 1805 AAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGF 1864
A + D+G P+ S G GP+ GA +Q P + GF
Sbjct: 847 AKGEQGEAGQKGDAGAPGPQGPSGAP--------GPQGPTGVTGPKGARGAQGPPGATGF 898
Query: 1865 RPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPP 1924
+ P S PPGP PS +G P
Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD---------------------SGP 937
Query: 1925 PSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFL-------------- 1970
P P P + D PS ++ P GQ G +
Sbjct: 938 PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 997
Query: 1971 --PSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQP---------- 2018
PSG P +Q P + G P P PP L+ GPA +P
Sbjct: 998 PGPSGEPGKQ--------GAPGAS-GDRGPPGPVGPPGLT----GPAGEPGREGSPGADG 1044
Query: 2019 ---------------PSLAVRPPPAPATRVLPSPARPFPASLGRAEL---------HPVE 2054
+ AV P AP P PA P R E P
Sbjct: 1045 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1104
Query: 2055 LKPFQDYQKLSSNLG--GPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQA 2112
+ Q Q + G G R R F+GL L P +
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG-LPGPPGPSGDQGASGPAGPSGPR 1163
Query: 2113 SPP--------DALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPP 2155
PP D IP P GP R G + A PG+ G P PP
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214
Score = 94.0 bits (232), Expect = 1e-18
Identities = 281/1171 (23%), Positives = 351/1171 (29%), Gaps = 336/1171 (28%)
Query: 60 ANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPAS 119
A P +K E+ N S P G ++ ++ P + A+ A+ + QP PA
Sbjct: 302 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP--AGAAGARGNDGQPGPAG----- 354
Query: 120 NQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQ 179
PP P+ P+G + A GA G+ G PT A
Sbjct: 355 -----PPG-----PVGPAGGPGFPGAP---GAKGEAG--------------PT--GARGP 385
Query: 180 DKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSG 239
+ A R PGP+ G G D + G G +G
Sbjct: 386 EGAQGPRGEPGTPGSPGPA---------GASGNPGTDGIPGAKGSA-------GAPGIAG 429
Query: 240 PPQFPPYRGMMPPFMYPPYLPFPPP-----------YGPQGPYRYPTPDGPSRFPRVAGP 288
P FP RG PP P P G QGP P P GP P AG
Sbjct: 430 APGFPGPRG--PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE 487
Query: 289 RGS----GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDE 344
G G P V P+G P
Sbjct: 488 EGKRGARGEPGG-VGPIGPPG--------------------------------------- 507
Query: 345 EDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPG 404
E GA G+R G P A G++G S + PK A + RP EPG
Sbjct: 508 -------ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA---GPKGANGDPGRP--GEPG 555
Query: 405 PPAPKPPL-PPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463
P + P GP G GP G + G P PP P+ R Q
Sbjct: 556 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQG-------ARGQPG-----V 601
Query: 464 VERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTP-APPP 522
+ + E E+ A L+ L K G PA P AP P
Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661
Query: 523 AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSG 582
+ + LP PP P P + PG A AP LV G
Sbjct: 662 SGFQGLPGPPGP--------------PGEGGKPGDQGVPGEAGAPGLVGPRGE------- 700
Query: 583 SFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKS 642
P E P +G + P + P TP PKG GP P +QG
Sbjct: 701 --RGFPGERGSPGAQGLQGPRGL--PGTPGTD--GPKG-ASGPAGPPGAQG--------- 744
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPP-----------SPPQPVTLGAVP 691
PP Q E+ + + G P P PP P
Sbjct: 745 -PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEK 803
Query: 692 APQAPPPPPKAL----YPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747
PP P + PG G P P F PPG
Sbjct: 804 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG-----------------------PPG 840
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLT 807
E+ ++G + D AP G P P P +T
Sbjct: 841 ADGQPGAKGEQGEAG----QKGDAGAPGPQGPSGAP---------------GPQGPTGVT 881
Query: 808 SPLRQAADEDDKGMR-SETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGP---R 862
P KG R ++ PP P A G P NG PGPP P + GP R
Sbjct: 882 GP---------KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 932
Query: 863 PLPWPPGSDEVAKIQ---TPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQ----GPPP 915
PPG +Q PP +K P ++ GP P G GQ G P
Sbjct: 933 GDSGPPGRAGEPGLQGPAGPPGEKGEPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPG 987
Query: 916 PRRESRTETRWGPRPGSSRRGIP-------PEEPGAPPRRAGPIKKPPPPTKVEELPPKP 968
R E GP ++G P P P PP GP +P E P
Sbjct: 988 QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR----EGSPGAD 1043
Query: 969 LEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGR 1028
G + K D + G +G P P G+ PA GPT +G R
Sbjct: 1044 GPPGRDGAAGVKGD--RGETGAVGAPGAPGPPGSPGPA------------GPTGKQG-DR 1088
Query: 1029 GEYFARG----------RGFRGTYGGRGRGARS-----REFRSYREF------------R 1061
GE A+G RG +G G RG + R + +R F
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148
Query: 1062 GDDGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAP 1119
GD G G G GP PP P G + + + G P R R ETG
Sbjct: 1149 GDQGASGPAGPSGPRGPPGPVGPSGKD-GANGIPGPIGPPGPRGRSGETG---------- 1197
Query: 1120 SDKEAPTPKEGTLTQVPLAPPPPGAPPSPAP 1150
P G P PPG P P P
Sbjct: 1198 -----PAGPPGN-------PGPPGPPGPPGP 1216
Score = 70.1 bits (170), Expect = 2e-11
Identities = 231/957 (24%), Positives = 290/957 (30%), Gaps = 249/957 (26%)
Query: 80 PKDGTG-WASKQEQSDPKSSDASTAQPPESQPLPASQT----PASNQPKR---------- 124
P+ TG K + +P + Q P+ +P PA PA + KR
Sbjct: 442 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501
Query: 125 ---PPA---APENT----------PLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSRE 168
PP AP N P G + + + GA+GD GR +R
Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 561
Query: 169 EFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEG-PDSKLHH 227
AG Q K E PGP PQ G RG + G P K +
Sbjct: 562 LTGRPGDAGPQGKVGPSGAPGEDGR-PGPP-GPQ--------GARGQPGVMGFPGPKGAN 611
Query: 228 GHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAG 287
G + G G P P RG+ P P GP G GPS F + G
Sbjct: 612 GEPGKAG--EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 669
Query: 288 PRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347
P GPP +P D G G
Sbjct: 670 P--PGPPGEGGKP---------------------GDQGVPG------------------- 687
Query: 348 RDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPA 407
++ G G R + GE P A G +G P P TP T + + P PG
Sbjct: 688 -EAGAPGLVGPRGERGFPGERGSPGAQGLQG--PRGLPGTPGTDGPKGASGPAGPPGAQG 744
Query: 408 PKPPLP--PPHRGPAGNWGPPGDYPDRG--GP--------------PCKPPAPEDEDEAW 449
P P L P RG AG GP GD D G GP P PP P
Sbjct: 745 P-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP------- 796
Query: 450 RQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP- 508
A E+ E +A A GAP +R + P
Sbjct: 797 -----------------AGANGEKGEVGPPGPAGSAGAR---------GAPGERGETGPP 830
Query: 509 -----AAPPAAPSTP----------------APPPAVPKELPAPPAPPPASAPTPETEPE 547
A PP A P AP P P P P P + P +
Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP----KGA 886
Query: 548 EPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP--EEV 605
AQ PP +T PG A G S P P K+GP+ +
Sbjct: 887 RGAQGPPG-ATGFPGAA---------GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936
Query: 606 PP----------PTTPPVPKVEPKGDGIGPTRQPPS-QGLGYPKYQKSLPPRFQRQQQEQ 654
PP P PP K EP DG PP QGL + LP Q+ E+
Sbjct: 937 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG----QRGER 992
Query: 655 LLKQQQQHQWQQHQQGS-------APPTPV-PPSPPQPV-TLGAVPAPQAPPPPPK---- 701
+ +QG+ PP PV PP P G +P A PP +
Sbjct: 993 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA 1052
Query: 702 -----ALYPGALGRP-PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV- 754
GA+G P P PP + P P QG + PSG
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPGP--------AGPTGKQGDRGEAGAQGPMGPSGPAG 1104
Query: 755 ------PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
P+ G + EP +R G + GD + PA P
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164
Query: 809 PLRQAADEDDKGMRSETPPVPPPPPY-------LASYPGFP-ENGAPGPP-----ISRFP 855
P G P+ PP P A PG P G PGPP +S F
Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1224
Query: 856 ---LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP----KEETAQLTGPEAGRK-PAR 904
E GP PL + ++ + + + + PE RK PAR
Sbjct: 1225 GLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPAR 1281
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 142 bits (359), Expect = 3e-33
Identities = 322/1302 (24%), Positives = 410/1302 (31%), Gaps = 232/1302 (17%)
Query: 522 PAVPKELPAPPAPPPASAPTPETEP--------EEPAQAPPAQS----TP----TPGVAA 565
P K++ P PP P E P E+ A P + TP PG
Sbjct: 40 PGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG 99
Query: 566 APTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI-G 624
P GG+ ++ +G F+ QL +GP P P PP P P G G
Sbjct: 100 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG---PRGPPGPAGAPGPQGFQG 156
Query: 625 PTRQPPSQGLGYPKYQKSLP--PRFQRQQQEQLLKQQQQHQWQQHQQGSA--PPTPVPPS 680
+P G+ P + P P E + + QG+ P TP P
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 216
Query: 681 PP----QPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQ 736
P GA AP ++ PG G P PM P P
Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE----RGRTGPAGAA 272
Query: 737 GRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERG-TPPVDPKLAWVGDV 795
G D P P G V G + P AP E G T P+ A
Sbjct: 273 GARGNDGQPGPAGPPGPV--------GPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRG 324
Query: 796 FTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRF 854
TP P P + D S P +A PGFP G PGP +
Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG------IAGAPGFPGPRGPPGPQGATG 378
Query: 855 PLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPP 914
PL GP+ PG Q P + P + A E G++ ARG GG GP
Sbjct: 379 PL---GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE-PGGVGPI 434
Query: 915 PPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPP---PTKVEELPPKPLEQ 971
P G R RG P ++ A P+ A + P P P +P E
Sbjct: 435 GPP---------GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485
Query: 972 GDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEY 1031
G L +G G P + P G + P+ D GP RG+
Sbjct: 486 G-----------LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ----- 529
Query: 1032 FARGRGFRGTYGGRGRGARSRE--FRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASET 1087
GF G G G ++ E RG G+ G TG GP P P G +
Sbjct: 530 -PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 588
Query: 1088 RSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS 1147
S ++ +P G E G P D+ P GAP
Sbjct: 589 APGPSGFQGLPGPPGPPG-EGGK--------PGDQGVPGEA--------------GAPGL 625
Query: 1148 PAPARFTARGGRVFT-PRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSK 1206
P RG R F RG P +G G R P PG P + P PP PP
Sbjct: 626 VGP-----RGERGFPGERGSPGAQGLQGPRGLPGT-PGTDGPKGASGPAGPPGAQGPPGL 679
Query: 1207 EPLKEKL----IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQ 1262
+ + + I GP G G +DG R G PP
Sbjct: 680 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG-------PPG-----P 727
Query: 1263 ERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWE 1322
N +G G P PA + G A P A P ++ E+ E
Sbjct: 728 AGANGEKGEVGPPG---PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 784
Query: 1323 TASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSK 1382
++GD AP P G PG G V G A
Sbjct: 785 AG---------QKGDAGAPGP----QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831
Query: 1383 RSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRP 1442
+ PG PGP G +G G G GP GR G + P P + P
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP-PGEKGEP 890
Query: 1443 PEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH-PRHKP 1501
++ P G PP P L+ ++G V PG R P
Sbjct: 891 GDDGPSGAEGPPGPQG------------------------LAGQRGIVGLPGQRGERGFP 926
Query: 1502 GLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM----VRGVGGTP-RDSAGVSPF 1556
GLP GPS P + P G S D PGP+ + G G P R+ + +
Sbjct: 927 GLP----GPSGEPGKQGAP-----GASGDRG--PPGPVGPPGLTGPAGEPGREGSPGADG 975
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSK-PEGP-GPQAESRDTGTEALTPHIWNRL 1614
PP R K + + ++ P + G GS P GP G Q + + G +
Sbjct: 976 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG--------- 1026
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
P+ P AG Q G GD + P +
Sbjct: 1027 -------------------PMGP-SGPAGARGIQGPQGP--RGDKGEAGEPGERGLKGHR 1064
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
G G +G P PG S A GP G PR PP P K+ P P GP G
Sbjct: 1065 GFTGL-QGLPGPPGPSGDQGA---SGPAGPSGPRGPP-GPVGPSGKDGANGIPGPIGPPG 1119
Query: 1735 TERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVG 1776
R E GP P PGPP G D+ G
Sbjct: 1120 PR-----GRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAG 1156
Score = 126 bits (316), Expect = 3e-28
Identities = 305/1226 (24%), Positives = 385/1226 (31%), Gaps = 264/1226 (21%)
Query: 352 EEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP----------------------K 389
E+G G R + G P DG+ G N PP P +
Sbjct: 61 EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDE 120
Query: 390 TAWAETSRPPETEPGPPAPK-PPLPPPHRGPAGNWGPPGDYPDRG--------GPPCKPP 440
A + GP P+ PP P GP G G PG+ + G GPP P
Sbjct: 121 KAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG 180
Query: 441 APEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAP 500
P D+ EA + + + + AR + R L + GAP
Sbjct: 181 KPGDDGEAGKPGK--AGERGPPGPQGARGFPGTPGLPGVKGHRGYPG--LDGAKGEAGAP 236
Query: 501 DKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP-PASAPTPETEPEEPAQA-PPAQST 558
+K E +P S P P P+ LP PA A +P A PP
Sbjct: 237 G--VKGESGSPGENGS---PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG 291
Query: 559 PT--PGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKV 616
P PG AP G T + + EP P GP P P K
Sbjct: 292 PAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKG 351
Query: 617 EPKGDGI-------GPTRQPPSQGLGYPKYQKSL--PPRFQRQQQEQLLKQQQQHQWQQH 667
GI GP P QG P K P + EQ K + Q
Sbjct: 352 SAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG 411
Query: 668 QQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPM------------- 714
G A + +P +G + P P +PG G P
Sbjct: 412 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 471
Query: 715 -PPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG-VHPSGLVPRERSDSGGSSSEPFDRH 772
N DP P R L GRP D P G V PSG P E G
Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPG-DAGPQGKVGPSG-APGEDGRPG---------- 519
Query: 773 APAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPP 832
P RG P V + + G EP +KG+ P
Sbjct: 520 PPGPQGARGQPGV---MGFPGP--KGANGEP----------GKAGEKGL--------PGA 556
Query: 833 PYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEE-- 889
P L PG E GA GPP P E G + P P G + PP + P ++
Sbjct: 557 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV 616
Query: 890 -----TAQLTGPEAGRK-PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPG 943
L GP R P G QG PR T GP+ S P
Sbjct: 617 PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG--------PA 668
Query: 944 APPRRAGP--IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNG 1001
PP GP ++ P + ++GD K P+ P GK GG T P G
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP-----GKDGGRGLTGPIG 723
Query: 1002 NLSPAPRLRRDYSYERVGPTSCRG-RG----RGEYFARG-RGFRGTYGGRGR-GARSREF 1054
PA GP G RG RGE G GF G G G+ GA+ +
Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783
Query: 1055 RSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIP---------KRRRQRG 1105
+ + +GD G G GP+ P P+G T T +G+ + P R
Sbjct: 784 EAGQ--KGDAG-APGPQGPSGAPGPQGPT-GVTGPKGARGAQGPPGATGFPGAAGRVGPP 839
Query: 1106 SETGSETHESDLAPSDKEAPTPKEGTL----------TQVPLAPP----------PPGAP 1145
G+ PS K+ P G Q P PP P GA
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE 899
Query: 1146 PSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLP 1203
P P + G V G+P +RG G G P P PG A + + P GP+
Sbjct: 900 GPPGPQGLAGQRGIV----GLPGQRGERGFPGLPGPSGEPG-KQGAPGASGDRGPPGPVG 954
Query: 1204 PSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQE 1263
P + GP R GS G D PP
Sbjct: 955 PPG-------LTGPAGEPGREGSPGA----------------------DGPP-------G 978
Query: 1264 RENAA--RGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
R+ AA +G G+ APGP +P P K D
Sbjct: 979 RDGAAGVKGDRGETGAVGAPGAPGPPG-------SPGPAGPTGKQGD------------- 1018
Query: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLS 1381
RG+ A P +G G G + G RGD + A +
Sbjct: 1019 -------------RGEAGAQGP-------MGPSGPAGARGIQGPQG-PRGDKGE-AGEPG 1056
Query: 1382 KRSFSSQR--PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSW------ 1433
+R R G++ PGP G G+SG + G GP G GP D +
Sbjct: 1057 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1116
Query: 1434 -PSPKNRS-RPPEERPPGLPLPPPPP 1457
P P+ RS PPG P PP PP
Sbjct: 1117 PPGPRGRSGETGPAGPPGNPGPPGPP 1142
Score = 116 bits (290), Expect = 3e-25
Identities = 306/1203 (25%), Positives = 389/1203 (32%), Gaps = 197/1203 (16%)
Query: 132 TPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQ 191
T LV + ++ Q G G G + + P Q + +R +
Sbjct: 14 TLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 73
Query: 192 SSGPGPSLRPQNSTTWRDGGGRGPDELEGPD-------SKLHHGHDPR-GGLQ------P 237
PGP R T + G GP GP +++ G D + GG Q P
Sbjct: 74 KGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGP 133
Query: 238 SGP--PQFPPYRGMMPP---FMYPPYLPFPP-------PYGPQGPYRYPTPDGPSRFPRV 285
GP P+ PP P F P P P P GP GP P DG + P
Sbjct: 134 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 193
Query: 286 AGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDD-------GWAGAHEEVDYTEK 338
AG RG P G P + + + LD + G +G+ E
Sbjct: 194 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 253
Query: 339 L--KFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAET- 395
+ + E GR + GA G R + G PP G G P K T
Sbjct: 254 MGPRGLPGERGR-TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 312
Query: 396 SRPPETEPG----PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGP----------PCKPPA 441
+R PE G P P P P G G G PG G P P PP
Sbjct: 313 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 372
Query: 442 PEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPD 501
P+ K + E +A + + + E + A + + K GA
Sbjct: 373 PQGATGPLGP--KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE----EGKRGARG 426
Query: 502 KRLKAEPAAPP---AAPSTPAPPP----AVPKELPAPPAPPPASAPT-PETEPEEPAQAP 553
+ P PP AP P A PK P P + P +P P +
Sbjct: 427 EPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGE-- 484
Query: 554 PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV 613
PG+ A L G +P E P GP+ P P
Sbjct: 485 -------PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537
Query: 614 PKVEPKGDG-IGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
PK G G P + GL + LP + + G+A
Sbjct: 538 PKGANGEPGKAGEKGLPGAPGL------RGLPGK-------------------DGETGAA 572
Query: 673 -PPTPVPPS-------PPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWM 724
PP P P+ P P +P P P PP + PG G P
Sbjct: 573 GPPGPAGPAGERGEQGAPGPSGFQGLPGP--PGPPGEGGKPGDQGVPGEAG--------- 621
Query: 725 MIPPYVDPRLLQGRPPLDFYPPGVH----PSGLVPRERSD----SGGSSSEPFDRHAP-- 774
P V PR +G P + PG P GL +D + G + P + P
Sbjct: 622 -APGLVGPRGERGFPG-ERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679
Query: 775 -AMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPP 833
M ERG + GDV E P +P + G R T P+ PP P
Sbjct: 680 QGMPGERGAAGIAGPKGDRGDV-----GEKGPEGAPGKD-------GGRGLTGPIGPPGP 727
Query: 834 YLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQL 893
A+ E G PGP S PG R PPG A PP P + Q
Sbjct: 728 AGANGEK-GEVGPPGPAGSAGARGAPGERGETGPPGP---AGFAGPPGADGQPGAKGEQ- 782
Query: 894 TGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIK 953
EAG+K G G QGP GP+ +G PP G P AG +
Sbjct: 783 --GEAGQKGDAG-APGPQGPSGAPGPQGPTGVTGPKGARGAQG-PPGATGF-PGAAGRV- 836
Query: 954 KPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDY 1013
PP + PP P P P D K +G G P G PA
Sbjct: 837 -GPPGSNGNPGPPGP-------PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888
Query: 1014 SYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG-- 1071
GP+ G + A RG G G RG R F G+ G+ G G
Sbjct: 889 EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG----ERGFPGLPGPSGEPGKQGAPGAS 944
Query: 1072 ---GPNHPPAPRGRT--ASETRSEGSEYEEIPKRR------RQRGSETGSETHESDLAPS 1120
GP P P G T A E EGS + P R + ETG+ P
Sbjct: 945 GDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP 1004
Query: 1121 DK---EAPTPKEGTL----TQVPLAPP-PPGAPPSPAPARFTARGGRVFTP--RGVPSRR 1170
PT K+G Q P+ P P GA P G P RG+ R
Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1064
Query: 1171 GRGG-----GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGG 1225
G G G P P G S PA P+ PP GP+ PS + IPGP+ P G
Sbjct: 1065 GFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP-GPVGPSGKD-GANGIPGPIGPPGPRG 1122
Query: 1226 SNG 1228
+G
Sbjct: 1123 RSG 1125
Score = 95.9 bits (237), Expect = 4e-19
Identities = 294/1251 (23%), Positives = 380/1251 (30%), Gaps = 301/1251 (24%)
Query: 1036 RGFRGTYGGRGR-GARSREFRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASETRSEGS 1092
RG RG G +G G R R+ G+ G G G GP PP P G +
Sbjct: 65 RGDRGDKGEKGAPGPRGRD--------GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAG 116
Query: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA--- 1149
++E + G++ G + Q P+ P P PP PA
Sbjct: 117 GFDE-----KAGGAQLG----------------------VMQGPMGPMGPRGPPGPAGAP 149
Query: 1150 -PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEP 1208
P F G G P G G R PP P P A K G P P
Sbjct: 150 GPQGFQGNPGEP----GEPGVSGPMGPRGPPG--PPGKPGDDGEAGKPGKAGERGPPG-P 202
Query: 1209 LKEKLIPG-PLSPVARG-----------GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPR 1256
+ PG P P +G G G V E G G + P
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262
Query: 1257 FRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQ 1316
R ARG++G+P PA PGP V PA +P
Sbjct: 263 RGRTGPAGAAGARGNDGQPG---PAGPPGP--------VGPAGGPGFPGAPGAKG----- 306
Query: 1317 ANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQR 1376
E T + + RG+ P G+PG G PG + S
Sbjct: 307 --EAGPTGARGPEGAQGPRGEPGTP----------GSPGPAGASGNPGTDGIPGAKGSAG 354
Query: 1377 AKDLSKR-SFSSQR--PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSW 1433
A ++ F R PG + GP G+ G G + G GP G GP
Sbjct: 355 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 414
Query: 1434 PSPKNRSRPPEERPPGL-PLPPP----PPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQG 1488
P+ + R P G+ P+ PP P + D + A ++ + L+ +G
Sbjct: 415 PAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474
Query: 1489 SVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVN-SGL-SSDPHFEEPGPMVRGVGGT 1546
+ PG +PGLP A +G + RP +V SG D PGP +G G
Sbjct: 475 ANGDPGRPG--EPGLPGA-RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP--QGARGQ 529
Query: 1547 PRDSAGVSPFP-PKRRERPPRKPELLQEESLPP-------PHSSGFLGSK-PEGP-GPQA 1596
P GV FP PK P K E+ LP P G G+ P GP GP
Sbjct: 530 P----GVMGFPGPKGANGEPGKAG---EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 582
Query: 1597 ESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLS 1656
E + G PS + P P G D GV
Sbjct: 583 ERGEQGAPG-------------------PSGFQGLPGPPGP----PGEGGKPGDQGVPGE 619
Query: 1657 GDSQVSSGPCSQRSSP-DGGLKGAA--EGP---PKRPGGSSPLNAVPCEGPPGSEPPRRP 1710
+ GP +R P + G GA +GP P PG P A GPPG++ P
Sbjct: 620 AGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679
Query: 1711 PPAPHD----------GDRKELPREQPL----------------PPGPIGTERSQRTDRG 1744
P + GDR ++ + P PPGP G
Sbjct: 680 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA--------N 731
Query: 1745 TEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPS 1804
E G + P PGP G + + E A P D + P
Sbjct: 732 GEKGEVGP---PGPAGSAGARGAPGE---------RGETGPPGPAGFAGPPGADGQ--PG 777
Query: 1805 AAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGF 1864
A + D+G P+ S G GP+ GA +Q P + GF
Sbjct: 778 AKGEQGEAGQKGDAGAPGPQGPSGAP--------GPQGPTGVTGPKGARGAQGPPGATGF 829
Query: 1865 RPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPP 1924
+ P S PPGP PS +G P
Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD---------------------SGP 868
Query: 1925 PSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFL-------------- 1970
P P P + D PS ++ P GQ G +
Sbjct: 869 PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 928
Query: 1971 --PSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQP---------- 2018
PSG P +Q P + G P P PP L+ GPA +P
Sbjct: 929 PGPSGEPGKQ--------GAPGAS-GDRGPPGPVGPPGLT----GPAGEPGREGSPGADG 975
Query: 2019 ---------------PSLAVRPPPAPATRVLPSPARPFPASLGRAEL---------HPVE 2054
+ AV P AP P PA P R E P
Sbjct: 976 PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG 1035
Query: 2055 LKPFQDYQKLSSNLG--GPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQA 2112
+ Q Q + G G R R F+GL L P +
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQG-LPGPPGPSGDQGASGPAGPSGPR 1094
Query: 2113 SPP--------DALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPP 2155
PP D IP P GP R G + A PG+ G P PP
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145
Score = 94.0 bits (232), Expect = 1e-18
Identities = 281/1171 (23%), Positives = 351/1171 (29%), Gaps = 336/1171 (28%)
Query: 60 ANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPAS 119
A P +K E+ N S P G ++ ++ P + A+ A+ + QP PA
Sbjct: 233 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP--AGAAGARGNDGQPGPAG----- 285
Query: 120 NQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQ 179
PP P+ P+G + A GA G+ G PT A
Sbjct: 286 -----PPG-----PVGPAGGPGFPGAP---GAKGEAG--------------PT--GARGP 316
Query: 180 DKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSG 239
+ A R PGP+ G G D + G G +G
Sbjct: 317 EGAQGPRGEPGTPGSPGPA---------GASGNPGTDGIPGAKGSA-------GAPGIAG 360
Query: 240 PPQFPPYRGMMPPFMYPPYLPFPPP-----------YGPQGPYRYPTPDGPSRFPRVAGP 288
P FP RG PP P P G QGP P P GP P AG
Sbjct: 361 APGFPGPRG--PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE 418
Query: 289 RGS----GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDE 344
G G P V P+G P
Sbjct: 419 EGKRGARGEPGG-VGPIGPPG--------------------------------------- 438
Query: 345 EDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPG 404
E GA G+R G P A G++G S + PK A + RP EPG
Sbjct: 439 -------ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA---GPKGANGDPGRP--GEPG 486
Query: 405 PPAPKPPL-PPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463
P + P GP G GP G + G P PP P+ R Q
Sbjct: 487 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP--GPPGPQG-------ARGQPG-----V 532
Query: 464 VERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTP-APPP 522
+ + E E+ A L+ L K G PA P AP P
Sbjct: 533 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592
Query: 523 AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSG 582
+ + LP PP P P + PG A AP LV G
Sbjct: 593 SGFQGLPGPPGP--------------PGEGGKPGDQGVPGEAGAPGLVGPRGE------- 631
Query: 583 SFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKS 642
P E P +G + P + P TP PKG GP P +QG
Sbjct: 632 --RGFPGERGSPGAQGLQGPRGL--PGTPGTD--GPKG-ASGPAGPPGAQG--------- 675
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPP-----------SPPQPVTLGAVP 691
PP Q E+ + + G P P PP P
Sbjct: 676 -PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEK 734
Query: 692 APQAPPPPPKAL----YPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747
PP P + PG G P P F PPG
Sbjct: 735 GEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG-----------------------PPG 771
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLT 807
E+ ++G + D AP G P P P +T
Sbjct: 772 ADGQPGAKGEQGEAG----QKGDAGAPGPQGPSGAP---------------GPQGPTGVT 812
Query: 808 SPLRQAADEDDKGMR-SETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGP---R 862
P KG R ++ PP P A G P NG PGPP P + GP R
Sbjct: 813 GP---------KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 863
Query: 863 PLPWPPGSDEVAKIQ---TPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQ----GPPP 915
PPG +Q PP +K P ++ GP P G GQ G P
Sbjct: 864 GDSGPPGRAGEPGLQGPAGPPGEKGEPGDD-----GPSGAEGPPGPQGLAGQRGIVGLPG 918
Query: 916 PRRESRTETRWGPRPGSSRRGIP-------PEEPGAPPRRAGPIKKPPPPTKVEELPPKP 968
R E GP ++G P P P PP GP +P E P
Sbjct: 919 QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR----EGSPGAD 974
Query: 969 LEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGR 1028
G + K D + G +G P P G+ PA GPT +G R
Sbjct: 975 GPPGRDGAAGVKGD--RGETGAVGAPGAPGPPGSPGPA------------GPTGKQG-DR 1019
Query: 1029 GEYFARG----------RGFRGTYGGRGRGARS-----REFRSYREF------------R 1061
GE A+G RG +G G RG + R + +R F
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079
Query: 1062 GDDGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAP 1119
GD G G G GP PP P G + + + G P R R ETG
Sbjct: 1080 GDQGASGPAGPSGPRGPPGPVGPSGKD-GANGIPGPIGPPGPRGRSGETG---------- 1128
Query: 1120 SDKEAPTPKEGTLTQVPLAPPPPGAPPSPAP 1150
P G P PPG P P P
Sbjct: 1129 -----PAGPPGN-------PGPPGPPGPPGP 1147
Score = 72.4 bits (176), Expect = 4e-12
Identities = 181/696 (26%), Positives = 232/696 (33%), Gaps = 108/696 (15%)
Query: 1397 RRPGPGGKAGSSGS-------SSGGGGGGPGGRTGP--GRGDKRSWPSPKNRSRPPEERP 1447
R+PGP G+ G G G GP G GP RGDK +P R R E
Sbjct: 29 RQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88
Query: 1448 PGLPLPPPPPSSSAVFRLDQVIHSNPAG---IQQALAQLSSRQGSVTAPGGHPRHKPGLP 1504
PG P PP PP L + AG + AQL QG + G P
Sbjct: 89 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG---------P 139
Query: 1505 QAPQGPSPRP-PTRYEPQRVNSGLSSDPHFEEP-GPM-VRGVGGTPRDSAGVSPFPPKRR 1561
+ P GP+ P P ++ N G +P P GP G G P D G + P K
Sbjct: 140 RGPPGPAGAPGPQGFQG---NPGEPGEPGVSGPMGPRGPPGPPGKPGDD-GEAGKPGKAG 195
Query: 1562 ERPPRKPELLQ----EESLPPPHS----SGFLGSKPE--GPGPQAESRDTGTEAL----- 1606
ER P P+ + LP G G+K E PG + ES G
Sbjct: 196 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 255
Query: 1607 ---TPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEM-----SQSDSGVDLSGD 1658
P R A + + P P G ++ ++G +
Sbjct: 256 PRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG 315
Query: 1659 SQVSSGPCSQRSSPDGGLKGAAEGPPKR---PGGSSPLNAVPCEGPPGSEPPRRPPPAPH 1715
+ + GP + +P A G P PG A G PG P R PP P
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGP-RGPPGPQ 374
Query: 1716 DGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLV- 1774
P+ Q PG G + ++ +G EPGP P PGP + G + V
Sbjct: 375 GATGPLGPKGQTGEPGIAGF-KGEQGPKG-EPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432
Query: 1775 -VGD----SLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSG 1829
+G + A P E PS A P+ N D G EP G
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG--PKGANGDPGR-PGEPGLPG 489
Query: 1830 QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLP-PGPAPP 1888
R G AGP GA P G RPG P R QP + PGP
Sbjct: 490 ARGLTG-RPGDAGPQGKVGPSGA------PGEDG-RPGPPGPQGARGQPGVMGFPGP--- 538
Query: 1889 SALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQ 1948
KG + +A E G A G+ P + A P + + Q
Sbjct: 539 ---------KG--ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQ 587
Query: 1949 DLPSPSDFYSTPLQPG--GQSG-----FLPSGAPAQQMLLPMVDSQLP----------VV 1991
P PS F P PG G+ G +P A A ++ P + P +
Sbjct: 588 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 647
Query: 1992 NFGSLPPAPPPAPPPLSLLPVGP--ALQPPSLAVRP 2025
LP P P + P GP A PP L P
Sbjct: 648 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683
Score = 70.1 bits (170), Expect = 2e-11
Identities = 231/957 (24%), Positives = 290/957 (30%), Gaps = 249/957 (26%)
Query: 80 PKDGTG-WASKQEQSDPKSSDASTAQPPESQPLPASQT----PASNQPKR---------- 124
P+ TG K + +P + Q P+ +P PA PA + KR
Sbjct: 373 PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432
Query: 125 ---PPA---APENT----------PLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSRE 168
PP AP N P G + + + GA+GD GR +R
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492
Query: 169 EFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEG-PDSKLHH 227
AG Q K E PGP PQ G RG + G P K +
Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGR-PGPP-GPQ--------GARGQPGVMGFPGPKGAN 542
Query: 228 GHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAG 287
G + G G P P RG+ P P GP G GPS F + G
Sbjct: 543 GEPGKAG--EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 600
Query: 288 PRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347
P GPP +P D G G
Sbjct: 601 P--PGPPGEGGKP---------------------GDQGVPG------------------- 618
Query: 348 RDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPA 407
++ G G R + GE P A G +G P P TP T + + P PG
Sbjct: 619 -EAGAPGLVGPRGERGFPGERGSPGAQGLQG--PRGLPGTPGTDGPKGASGPAGPPGAQG 675
Query: 408 PKPPLP--PPHRGPAGNWGPPGDYPDRG--GP--------------PCKPPAPEDEDEAW 449
P P L P RG AG GP GD D G GP P PP P
Sbjct: 676 P-PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGP------- 727
Query: 450 RQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP- 508
A E+ E +A A GAP +R + P
Sbjct: 728 -----------------AGANGEKGEVGPPGPAGSAGAR---------GAPGERGETGPP 761
Query: 509 -----AAPPAAPSTP----------------APPPAVPKELPAPPAPPPASAPTPETEPE 547
A PP A P AP P P P P P + P +
Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP----KGA 817
Query: 548 EPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP--EEV 605
AQ PP +T PG A G S P P K+GP+ +
Sbjct: 818 RGAQGPPG-ATGFPGAA---------GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867
Query: 606 PP----------PTTPPVPKVEPKGDGIGPTRQPPS-QGLGYPKYQKSLPPRFQRQQQEQ 654
PP P PP K EP DG PP QGL + LP Q+ E+
Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG----QRGER 923
Query: 655 LLKQQQQHQWQQHQQGS-------APPTPV-PPSPPQPV-TLGAVPAPQAPPPPPK---- 701
+ +QG+ PP PV PP P G +P A PP +
Sbjct: 924 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA 983
Query: 702 -----ALYPGALGRP-PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV- 754
GA+G P P PP + P P QG + PSG
Sbjct: 984 GVKGDRGETGAVGAPGAPGPPGSPGP--------AGPTGKQGDRGEAGAQGPMGPSGPAG 1035
Query: 755 ------PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
P+ G + EP +R G + GD + PA P
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095
Query: 809 PLRQAADEDDKGMRSETPPVPPPPPY-------LASYPGFP-ENGAPGPP-----ISRFP 855
P G P+ PP P A PG P G PGPP +S F
Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFA 1155
Query: 856 ---LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP----KEETAQLTGPEAGRK-PAR 904
E GP PL + ++ + + + + PE RK PAR
Sbjct: 1156 GLGPREKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNPAR 1212
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 142 bits (359), Expect = 3e-33
Identities = 371/1495 (24%), Positives = 474/1495 (31%), Gaps = 365/1495 (24%)
Query: 540 PTPETEPEEPAQAP---PAQSTPTPGVAAA-PTLVSGGGSTSSTSSGSFEASPVEP---- 591
PTP +P E A+ P + TPTP AA P G G G ++ P E
Sbjct: 290 PTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTP 349
Query: 592 ----QLPSKEGPEPPE---------EVPPPTTP------PVPKVEPKGDGIG-------- 624
L EG E P+ E+P T P P P G+G
Sbjct: 350 SPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAP---PPGEGADDLEGEFTE 406
Query: 625 ----------------PTRQPPSQGLGYPKYQKSL-----PPRFQRQQQEQ--LLKQQQQ 661
PT P G G P Q ++ PR ++ Q+ + +++
Sbjct: 407 ETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML 466
Query: 662 HQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDP 721
+ +G A P PP P G V P PP + PGA G P P M
Sbjct: 467 IEGPPGPEGPAG-LPGPPGTMGPT--GQVGDPGERGPPGRPGLPGADGLPGPPGTM---- 519
Query: 722 RWMMIP-------------PYVDPRLLQGRPPLDFY------PPGVHPSGLVPRERS--- 759
+M+P P V + Q + L P G P GL R
Sbjct: 520 --LMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG--PMGLTGRPGPVGP 575
Query: 760 -DSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQ--AADE 816
SGG EP D P P+ P P P R+ A +
Sbjct: 576 PGSGGLKGEPGD-----------VGPQGPR---------GVQGPPGPAGKPGRRGRAGSD 615
Query: 817 DDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSD-EVAK 875
+GM +T P GF +G G P + +PGP P PPG D E
Sbjct: 616 GARGMPGQTGP--------KGDRGF--DGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGD 665
Query: 876 IQTPPPKKEPPKEETAQLTGPEAGRKPARGVG-SGGQGPPPPRRESRTETRWGPRPGS-- 932
P+ P + L GP+ P G +G G P P+ + GP PG
Sbjct: 666 DGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP-PGQQG 724
Query: 933 --SRRGIP-PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKG 989
+G+P P+ PP GP+ KP LP P G PP + G
Sbjct: 725 NPGAQGLPGPQGAIGPPGEKGPLGKP-------GLPGMPGADG-----PPGHPGKEGPPG 772
Query: 990 KLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
+ GG P G + P PR + R G +G + F +G G G RG
Sbjct: 773 EKGGQGPPGPQGPIGYPGPRGVKGADGIR-GLKGTKGEKGEDGFPGFKGDMGIKGDRGEI 831
Query: 1049 ARSREFRSYREFRGDDGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS 1106
RG+DG G G GGPN P P G + + P R+ +GS
Sbjct: 832 GPPGP-------RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884
Query: 1107 -----------ETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTA 1155
E G P + PT G P G P P +
Sbjct: 885 IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRG-------ERGPRGITGKPGPKGNSG 937
Query: 1156 RGGRVFTPRGVPSRRGRGG-----GRPPPQVCPGWSPPAK-----------------SLA 1193
G P G P RG G G P P+ PG PP K
Sbjct: 938 GDG----PAGPPGERGPNGPQGPTGFPGPKGPPG--PPGKDGLPGHPGQRGETGFQGKTG 991
Query: 1194 PKKPP--TGPLPPSKE--PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
P PP GP P+ E P+ E+ PGP P G G + G+ G+
Sbjct: 992 PPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK-- 1049
Query: 1250 QQDKPPRFRRLKQER-------ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRA 1302
D PP R +R +G+EG P PA +PG P R
Sbjct: 1050 --DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP 1107
Query: 1303 AAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAV 1362
+ P A E+ + + R G + P VG PG G
Sbjct: 1108 GPQGP------PGPAGEKGAPGEKGPQGPAGRDG-LQGP---------VGLPGPAGPVGP 1151
Query: 1363 PGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGR 1422
PG +G++ + + SK Q P PGP G G G G G G
Sbjct: 1152 PGEDG-DKGEIGEPGQKGSKGDKGEQGP--------PGPTGPQGPIGQP---GPSGADGE 1199
Query: 1423 TGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ 1482
GP RG + + + +E P G P PP P G+Q
Sbjct: 1200 PGP-RGQQGLF------GQKGDEGPRGFPGPP-----------------GPVGLQ----G 1231
Query: 1483 LSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPG-PMVR 1541
L G G + P P P+GPS P PQ G+ + E G P
Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD-GPQGPPGGIGNPGAVGEKGEPGEA 1290
Query: 1542 GVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSK-PEG-PGPQAESR 1599
G G P + PP + K E + PP G G P+G PGP
Sbjct: 1291 GEPGLPGEGG-----PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345
Query: 1600 DTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDS 1659
D G P EP AG + D G D
Sbjct: 1346 DPG---------------------------PPGEP-----GPAGQDGPPGDKGDDGEPGQ 1373
Query: 1660 QVSSGPCSQ--RSSPDG--GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPH 1715
S GP + S P G G G A GP R G EGPPG P P AP
Sbjct: 1374 TGSPGPTGEPGPSGPPGKRGPPGPA-GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAP- 1431
Query: 1716 DGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVV 1775
K P PGP+G + + PGP P GPP L +
Sbjct: 1432 ---GKPGPDGLRGIPGPVGEQGLPGS-----PGPDGPPGPMGPP----------GLPGLK 1473
Query: 1776 GDS-LKAEKELTASVTEAIPVSRDWEL----LPSAAASAEPQSKNLDSGHCVPEPSSSGQ 1830
GDS K EK + P E LP S+ P+ + +G PS
Sbjct: 1474 GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG-----PSGPIG 1528
Query: 1831 RLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGP 1885
P G GP ++ S G P PG P PPGP
Sbjct: 1529 PPGPPGLPGPPGPKGAKGSSGPTG----PKGEAGHPGPPG-----------PPGP 1568
Score = 113 bits (282), Expect = 2e-24
Identities = 342/1452 (23%), Positives = 468/1452 (32%), Gaps = 303/1452 (20%)
Query: 67 AENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPP 126
+E G + +V + D + ++ P D T E P +QP P
Sbjct: 324 SEGAGKEEDVGIGDYD---YVPSEDYYTPSPYDDLTYGEGEENP---------DQPTDPG 371
Query: 127 AAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKER 186
A E +P+ + +S G+G A L F+ E L D++
Sbjct: 372 AGAE----IPTSTADTSNSSNPAPPPGEG--ADDLEGEFTEETIRNL----DENYYDPYY 421
Query: 187 ESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPY 246
+ S GP + T + GG PRG G P
Sbjct: 422 DPTSSPSEIGPGMPANQDTIYEGIGG------------------PRGEKGQKGEPA---- 459
Query: 247 RGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGP-SRFPRVAGPRGSGPPMRLVEPVGRPS 305
+ P + P GP+GP P P G +V P GPP GRP
Sbjct: 460 -------IIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPP-------GRPG 505
Query: 306 ILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSAS 365
+ D L G G + + +F G D+ +G S
Sbjct: 506 LPGADGLP-----------GPPGTMLMLPF----RFGG---GGDAGSKGP-------MVS 540
Query: 366 GEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGP 425
+E +A ++ P P T RP P+ PP G G G
Sbjct: 541 AQESQAQAILQQARLALRGPAGPMGL---TGRPG-----------PVGPP--GSGGLKGE 584
Query: 426 PGDYPDRGGPPCK-PPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRA 484
PGD +G + PP P + RR ++ S+ + + + + R +
Sbjct: 585 PGDVGPQGPRGVQGPPGPAGKPG----RRGRAGSDGARGMPGQTGPKGD---RGFDGLAG 637
Query: 485 ACAEKLKRLDEKFGAPD-------KRLKAEPAAPPAAPSTPAPPPAV-PKELPAPPAPP- 535
EK R D P +R P P P P + PK P PP PP
Sbjct: 638 LPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697
Query: 536 ---------PASAPTPETEPEEPAQA--PPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSF 584
P P+ EP P Q P AQ P P A P G
Sbjct: 698 VTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP--GEKGPLGKPGLPGM 755
Query: 585 EASPVEPQLPSKEGP--EPPEEVPPPTTPPVPKVEPKG----DGIGPTRQPPSQGL--GY 636
+ P P KEGP E + PP P+ P+G DGI + + G+
Sbjct: 756 PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF 815
Query: 637 PKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAP 696
P ++ + + R + + + +G P P PP G + P P
Sbjct: 816 PGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK--GKLGVPGLP 873
Query: 697 PPP----PKAL-----YPGALG----RPPPMPPMNFDPRWMMIPPYV----DPRLLQGRP 739
P PK +PGA G R P P PR P PR + G+P
Sbjct: 874 GYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKP---GPRGQRGPTGPRGERGPRGITGKP 930
Query: 740 PLDFYPPGVHPSGLVPRERSDSG--GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFT 797
G P+G P ER +G G + P + P + G P + G
Sbjct: 931 GPKGNSGGDGPAG-PPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 989
Query: 798 ATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP----ENGAPGPPISR 853
P P + P + G R P PP PP PG G PGP +
Sbjct: 990 TGPPGPPGVVGPQGPTGETGPMGERGH--PGPPGPPGEQGLPGLAGKEGTKGDPGP--AG 1045
Query: 854 FPLEE--------PGPRPLPWPPGSDEVAKIQTPP----PKKEPPKEETAQLTGPEAGRK 901
P ++ PG R LP P G+ + + PP P P + A GP
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG--I 1103
Query: 902 PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKV 961
P R G QGPP P E GP+ + R G+ + P P AGP+ P
Sbjct: 1104 PGR---PGPQGPPGPAGEKGAPGEKGPQGPAGRDGL--QGPVGLPGPAGPVGPPGEDGDK 1158
Query: 962 EELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPT 1021
E+ G+ K K D KG+ G P T P G + D G
Sbjct: 1159 GEI-------GEPGQKGSKGD-----KGEQGPPGPTGPQGPIGQPGPSGAD------GEP 1200
Query: 1022 SCRGRGRGEYFARG----RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG-----G 1072
RG+ +G + +G RGF G G G + G G G TG G
Sbjct: 1201 GPRGQ-QGLFGQKGDEGPRGFPGPPGPVG----------LQGLPGPPGEKGETGDVGQMG 1249
Query: 1073 PNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLA----PSDKEAPTPK 1128
P PP PRG + + G++ + P G + + P + P PK
Sbjct: 1250 PPGPPGPRGPSGAP----GADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPK 1305
Query: 1129 -----EGTLTQVPLAPPP-PGAPP-------SPAPARFTARGGRVFTPRGVPSRRGRGGG 1175
+G A PP P PP SP P F G P G P G+ G
Sbjct: 1306 GERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPG----PPGEPGPAGQDG- 1360
Query: 1176 RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGME 1235
PP P ++ +P PTG PS P K PGP P R G G
Sbjct: 1361 --PPGDKGDDGEPGQTGSPG--PTGEPGPSGPPGKRGP-PGPAGPEGRQGEKGAK----- 1410
Query: 1236 DGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP--EEALTTV 1293
G A + P + + +G+ GKP PGP E+ L
Sbjct: 1411 ----------GEAGLEGPPGKTGPI------GPQGAPGKPGPDGLRGIPGPVGEQGLPG- 1453
Query: 1294 TVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGT 1353
+ P P L D S +G+K P + L +G
Sbjct: 1454 SPGPDGPPGPMGPPGLPGLKGD----------------SGPKGEKGHPGLIGL----IGP 1493
Query: 1354 PGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSG 1413
PG G G+ + + ++ S PG PGP G GSSG +
Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP 1553
Query: 1414 GGGGGPGGRTGP 1425
G G G GP
Sbjct: 1554 KGEAGHPGPPGP 1565
Score = 90.9 bits (224), Expect = 1e-17
Identities = 228/904 (25%), Positives = 278/904 (30%), Gaps = 201/904 (22%)
Query: 211 GGRGPDELEGPDSKLHHGHDPRGGLQPSGP------PQFPPYRGMMPPFMYPPYLPFPPP 264
G RG D EGP + DP G L P G P P Y G P + FP
Sbjct: 835 GPRGEDGPEGPKGRGGPNGDP-GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGA 893
Query: 265 YGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDD 324
G +G P GP GPRG P + G+P D
Sbjct: 894 NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT---GKPG-----------PKGNSGGD 939
Query: 325 GWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE 384
G AG E G G + G + PP GK G P
Sbjct: 940 GPAGP--------------------PGERGPNGPQGPTGFPGPKGPPGPPGKDG-LPGHP 978
Query: 385 PPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPED 444
+T + + PP GPP P +GP G GP G+ RG P PP P
Sbjct: 979 GQRGETGFQGKTGPP----GPPGVVGP-----QGPTGETGPMGE---RGHPG--PPGPPG 1024
Query: 445 EDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRA---ACAEKLKRLDEK----- 496
E K+ + + R +R A LK +
Sbjct: 1025 EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPG 1084
Query: 497 -FGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPA 555
G+P +R A A P P P P PP P E P+ PA
Sbjct: 1085 PAGSPGERGPAGAAGPIGIPGRPGP--------QGPPGPAGEKGAPGEKGPQGPA----- 1131
Query: 556 QSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPK 615
G+ L G + EP +G + + P PT P
Sbjct: 1132 ---GRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ--- 1185
Query: 616 VEPKGDGIGPTRQP-PSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPP 674
GP QP PS G P PR Q Q Q+G P
Sbjct: 1186 --------GPIGQPGPSGADGEP------GPRGQ--------------QGLFGQKGDEGP 1217
Query: 675 TPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGR-PPPMPPMNFDPRWMMIPPYVDPR 733
P PP PV L +P PP + G +G+ PP PP PR
Sbjct: 1218 RGF-PGPPGPVGLQGLPG-----PPGEKGETGDVGQMGPPGPP--------------GPR 1257
Query: 734 LLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
G P D P P G+ + G EP + P + E G P + G
Sbjct: 1258 GPSGAPGAD--GPQGPPGGI---GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKG 1312
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
+ + P A KG + P P P GFP G PGPP
Sbjct: 1313 E------------SGPSGAAGPPGPKGPPGDDGPKGSPGPV-----GFP--GDPGPP--- 1350
Query: 854 FPLEEPGPRPLPWPPG--SDEVAKIQT--------PPPKKEPPKEETAQLTGPEA--GRK 901
EPGP PPG D+ QT P P P K GPE G K
Sbjct: 1351 ---GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407
Query: 902 PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP-PEEPGAPPRRAGPIKKPPPPTK 960
A+G +G +GPP + G RGIP P P GP P P
Sbjct: 1408 GAKG-EAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGP 1466
Query: 961 VEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-PAPRLRRDYSYER-- 1017
P P +GD PK K P I G +G P E G+ P P+ E+
Sbjct: 1467 ----PGLPGLKGDSGPKGEKGHPGLI--GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520
Query: 1018 VGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPP 1077
GP+ G G +G G G G G G G P PP
Sbjct: 1521 TGPSGPIGPPGPPGLPGPPGPKGAKGSSGP-------------TGPKGEAGHPGPPG-PP 1566
Query: 1078 APRG 1081
P G
Sbjct: 1567 GPPG 1570
Score = 56.2 bits (134), Expect = 3e-07
Identities = 104/407 (25%), Positives = 131/407 (32%), Gaps = 97/407 (23%)
Query: 96 KSSDASTAQPPESQ-PLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGD 154
++ D PP P S P ++ P+ PP N V G K + G G+
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV--GEKGEPGEAGEPGLPGE 1298
Query: 155 GGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSS--------GPGPSLRPQNSTT 206
GG R + E AAG + + S PGP P +
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358
Query: 207 WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPY-------- 258
G +G D G P G PSGPP RG PP P
Sbjct: 1359 DGPPGDKGDDGEPGQTGS----PGPTGEPGPSGPPG---KRG--PPGPAGPEGRQGEKGA 1409
Query: 259 -----LPFPP----PYGPQGPYRYPTPDGPSRFPRVAGPRG-------SGPPMRLVEPVG 302
L PP P GPQG P PDG P G +G GPP P+G
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP----GPMG 1465
Query: 303 RPSI--LKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRD 360
P + LK D+ + + G G + E+G +G R
Sbjct: 1466 PPGLPGLKGDS-------GPKGEKGHPGLIGLIG--------------PPGEQGEKGDRG 1504
Query: 361 SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA 420
G P G G S PP P PGPP PK G
Sbjct: 1505 LPGPQGSSGPKGEQGITGPSGPIGPPGPPGL-----------PGPPGPK--------GAK 1545
Query: 421 GNWGPPGDYPDRGGP-PCKPPAPEDE------DEAWRQRRKQSSSEI 460
G+ GP G + G P P PP P E +A R RR +S++
Sbjct: 1546 GSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQL 1592
Score = 54.3 bits (129), Expect = 1e-06
Identities = 152/623 (24%), Positives = 197/623 (31%), Gaps = 128/623 (20%)
Query: 36 PAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDG-----TGWASKQ 90
P GL L + P PA LP K P + P D G +
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPG-----KDGPPGLRGFPGDRGLPGPVGALGLK 1074
Query: 91 EQSDPKSSDASTAQPPESQPLPASQT---PASNQPKRPP-------AAPENTPLVPSGVK 140
P P E P A+ P P+ PP A E P P+G +
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAG-R 1133
Query: 141 SWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGP-GPSL 199
Q V G G G + E G K K + +GP GP
Sbjct: 1134 DGLQGPV--GLPGPAGPVGPPGEDGDKGEIGEPGQKGS--KGDKGEQGPPGPTGPQGPIG 1189
Query: 200 RPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQF-----PPYR------- 247
+P S + G RG L G PRG P GP PP
Sbjct: 1190 QPGPSGADGEPGPRGQQGLFGQKGD----EGPRGFPGPPGPVGLQGLPGPPGEKGETGDV 1245
Query: 248 GMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGS----GPPMRLVEP--- 300
G M P P P GP+GP P DGP P G G+ G P EP
Sbjct: 1246 GQMGP---------PGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296
Query: 301 -VGRPSILKEDNLKEFDQ-----------LDQENDDGWAGAHEEVDYTEKLKFSDE---- 344
G P K + ++ + DDG G+ V + E
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPA 1356
Query: 345 -EDGRDSD--EEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP---------KTAW 392
+DG D ++G G S +GE P GK+G PP P K A
Sbjct: 1357 GQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRG------PPGPAGPEGRQGEKGAK 1410
Query: 393 AETSR---PPETEPGPPAPKPPLPPPHR-----GPAGNWGPPGDYPDRGGP-PCKPPA-P 442
E P +T P P P P P GP G G PG G P P PP P
Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLP 1470
Query: 443 EDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDK 502
+ ++ + K I L + + E+ +R + + ++ + + + G
Sbjct: 1471 GLKGDSGPKGEKGHPGLIGL-IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSG---- 1525
Query: 503 RLKAEPAAPPAAPSTPAPP----------PAVPKELPAPPAPPPASAPTPETEPEEPAQA 552
P PP P P PP P PK P PP P P E Q
Sbjct: 1526 -----PIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGP-----PGEVIQP 1575
Query: 553 PPAQSTPT-PGVAAAPTLVSGGG 574
P Q++ T + A+ L G G
Sbjct: 1576 LPIQASRTRRNIDASQLLDDGNG 1598
Score = 40.8 bits (94), Expect = 0.015
Identities = 78/355 (21%), Positives = 108/355 (30%), Gaps = 70/355 (19%)
Query: 40 PRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSD 99
P G+ + G V + P A P L E P K +G + PK
Sbjct: 1271 PPGGIGNPGAVG-EKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPP 1329
Query: 100 ASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRAS 159
P+ P P P P A ++ P G + + G G+ G +
Sbjct: 1330 GDDG--PKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSG 1387
Query: 160 SLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELE 219
R P +K AK E G + PQ + G GPD L
Sbjct: 1388 PPGKR--GPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAP-----GKPGPDGLR 1440
Query: 220 G-----PDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPP-----------FMYPPY----- 258
G + L P G P GPP P +G P + PP
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500
Query: 259 ----LPFPP----------------PYGPQGPYRYPTPDGPSRFPRVAGPRG-------- 290
LP P P GP GP P P GP +GP G
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP 1560
Query: 291 -----SGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLK 340
GPP +++P+ + N+ LD N + + VDY + ++
Sbjct: 1561 GPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGNGENY------VDYADGME 1609
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 137 bits (345), Expect = 1e-31
Identities = 353/1394 (25%), Positives = 452/1394 (32%), Gaps = 258/1394 (18%)
Query: 511 PPAAPSTPAPP--PAVPKELPAP-PAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAP 567
PP P P P P +P AP P P T + P P PG P
Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP-PGPPGIP 152
Query: 568 TLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPK-----------V 616
+ GS +S + +P P P +G P +P P PP P
Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212
Query: 617 EPKGD-GI---GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
PKG+ G+ GP + QGL PP Q EQ K+ ++Q+ QG
Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGL-------QGPPGPPGQISEQ--KRPIDVEFQKGDQG-L 262
Query: 673 PPTPVPPSPPQPVTLGAVPAPQAPPPPPKALY-----PGALGRP--------PPMPPMNF 719
P PP PP + P PP K PG G+P P +P +
Sbjct: 263 PGDRGPPGPP------GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPG 316
Query: 720 DPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAM--- 776
DP + P + +G D PPG P GLV R +G + E + P +
Sbjct: 317 DPGYPGEPGRDGEKGQKG----DTGPPG--PPGLVI-PRPGTGITIGEKGNIGLPGLPGE 369
Query: 777 LRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPP--VPPPPPY 834
ERG P + G A P P P + KG E PP P PP
Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFP----GERGQKG--DEGPPGISIPGPPG 423
Query: 835 LASYPGFPENGAPGPPISRFP-------LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPK 887
L PG P G PGPP P + EPGP P PPGS +Q K
Sbjct: 424 LDGQPGAP--GLPGPPGPAGPHIPPSDEICEPGP---PGPPGSPGDKGLQGEQGVKGDKG 478
Query: 888 EETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--PEEPGAP 945
+ G P + G GPP + G + +G+P P PGAP
Sbjct: 479 DTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP 538
Query: 946 ------------------PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKIT 987
G + P P + LP P + G PK +P IT
Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGAPG-LPGLPGTPGQDGLPGLPGPKGEPGGIT 597
Query: 988 KGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGR 1047
G + P N L P GP G + A G G G +G
Sbjct: 598 ---FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD 654
Query: 1048 GARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSE 1107
++ G+ GR G G P P P G+ +P +G
Sbjct: 655 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP-GQPG------------LPGIPGSKG-- 699
Query: 1108 TGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVP 1167
E + P +G P P PPGAP +P G P G P
Sbjct: 700 ------EPGIPGIGLPGPPGPKG----FPGIPGPPGAPGTPGRIGLEGPPG----PPGFP 745
Query: 1168 SRRGRGG----GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVAR 1223
+G G G P P PG+ + P P PP + L +PGP V
Sbjct: 746 GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG--LPGPKGDVGP 803
Query: 1224 GGSNGGSN------VGMEDGERP--------RRRRHGRAQQQDKP--PRFRRLKQERENA 1267
G G +G++ P + HG ++ P P E
Sbjct: 804 NGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863
Query: 1268 ARGSEGKPSLTLPASAPG--------------PEEALTTVTVAPAPRRAAAKS--PDLSN 1311
+ G G P P +PG E + P P +S P L
Sbjct: 864 SPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKG 923
Query: 1312 QNSDQANE--EWETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPGISAM 1368
+ Q T + S +G+ P PP + P +G+ G G +PGI +
Sbjct: 924 DDGLQGQPGLPGPTGEKGS------KGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGV 977
Query: 1369 SRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRG 1428
S K +PG+ Q PGP G G+ G G GP G G G
Sbjct: 978 SG------PKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT-IG 1030
Query: 1429 DKRSWPSPKNRSRPP-------EERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALA 1481
D +P P+ PP + PGLP + + P G + L
Sbjct: 1031 DM-GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKG-EPGLP 1088
Query: 1482 QLSSR---QGSVTAPG-----GHPRHK--PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDP 1531
+GSV PG G P K PGLP P P P P N GL
Sbjct: 1089 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPG-- 1146
Query: 1532 HFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEG 1591
EPGP+ G GG P P PP + +P + P GF P G
Sbjct: 1147 ---EPGPV--GGGGHPG-----QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196
Query: 1592 -PGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEP-LSPFEDVAGTEMSQS 1649
PG + D G + + P P EP F V G
Sbjct: 1197 LPGLSGQKGDGGLPGIPGN---------------PGLPGPKGEPGFHGFPGVQGPPGPPG 1241
Query: 1650 DSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPG-----------GSSPLNAVP- 1697
G L G + + GP P GL G EGPP PG G L +P
Sbjct: 1242 SPGPALEG-PKGNPGPQGPPGRP--GLPG-PEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297
Query: 1698 ---CEGPPGSE-PPRRPPPAPHDGDRKELPREQPLP--PGPIGTERSQRTDRGTEPGPIR 1751
+GPPG + P RP GD LP P GP G S + EPG I
Sbjct: 1298 LKGDQGPPGLQGNPGRPGLNGMKGD-PGLPGVPGFPGMKGPSGVPGSAGPE--GEPGLIG 1354
Query: 1752 PSHRPGPPVQFGTS 1765
P PG P G S
Sbjct: 1355 PPGPPGLPGPSGQS 1368
Score = 134 bits (336), Expect = 1e-30
Identities = 366/1480 (24%), Positives = 467/1480 (31%), Gaps = 333/1480 (22%)
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP 413
G EGH G E PP G+KG+ + PGPP PK
Sbjct: 54 GLEGHPGLPGFPGPEGPPGPRGQKGD--------------------DGIPGPPGPKGI-- 91
Query: 414 PPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREE 473
RGP G G PG P G P AP + K
Sbjct: 92 ---RGPPGLPGFPGT-PGLPGMPGHDGAPGPQGIPGCNGTKG------------------ 129
Query: 474 EERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAV-PKELPAPP 532
ER G+P P PP P P ++ LP P
Sbjct: 130 -ERGFP------------------GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPK 170
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ 592
P P P Q P PT + G P+ P
Sbjct: 171 GNPGYPGP------------PGIQGLP------GPTGIPG---------------PIGP- 196
Query: 593 LPSKEGPEPPEEVPPPTTPPVPKVEPKGD-GI---GPTRQPPSQGLGYPKYQKSLPPRFQ 648
P PP + PP P +P PKG+ G+ GP + QGL PP
Sbjct: 197 ------PGPPGLMGPPGPPGLP--GPKGNMGLNFQGPKGEKGEQGL-------QGPPGPP 241
Query: 649 RQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKAL----- 703
Q EQ K+ ++Q+ QG P PP PP + P PP K
Sbjct: 242 GQISEQ--KRPIDVEFQKGDQG-LPGDRGPPGPP------GIRGPPGPPGGEKGEKGEQG 292
Query: 704 YPGALGRP--------PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVP 755
PG G+P P +P + DP + P + +G D PPG P GLV
Sbjct: 293 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKG----DTGPPG--PPGLV- 345
Query: 756 RERSDSGGSSSEPFDRHAPAM---LRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQ 812
R +G + E + P + ERG P + G A P P P
Sbjct: 346 IPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFP--- 402
Query: 813 AADEDDKGMRSETPP--VPPPPPYLASYPGFPENGAPGPPISRFP-------LEEPGPRP 863
+ KG E PP P PP L PG P G PGPP P + EPGP
Sbjct: 403 -GERGQKG--DEGPPGISIPGPPGLDGQPGAP--GLPGPPGPAGPHIPPSDEICEPGP-- 455
Query: 864 LPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTE 923
P PPGS +Q K + G P + G GPP +
Sbjct: 456 -PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514
Query: 924 TRWGPRPGSSRRGIP--PEEPGAP------------------PRRAGPIKKPPPPTKVEE 963
G + +G+P P PGAP G + P P +
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP-GLPG 573
Query: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSC 1023
LP P + G PK +P IT G + P N L P GP
Sbjct: 574 LPGTPGQDGLPGLPGPKGEPGGIT---FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGP 630
Query: 1024 RGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRT 1083
G + A G G G +G ++ G+ GR G G P P P G+
Sbjct: 631 VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP-GQP 689
Query: 1084 ASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPG 1143
+P +G E + P +G P P PPG
Sbjct: 690 G------------LPGIPGSKG--------EPGIPGIGLPGPPGPKG----FPGIPGPPG 725
Query: 1144 APPSPAPARFTARGGRVFTPRGVPSRRGRGG----GRPPPQVCPGWSPPAKSLAPKKPPT 1199
AP +P G P G P +G G G P P PG+ + P
Sbjct: 726 APGTPGRIGLEGPPG----PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPG 781
Query: 1200 GPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRR 1259
P PP + L +PGP V G G M P G P +
Sbjct: 782 PPGPPGRTGLDG--LPGPKGDVGPNGQPG----PMGPPGLPGIGVQGPPGPPGIPGPIGQ 835
Query: 1260 LKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANE 1319
+G G P L +P P E + AP P SP L
Sbjct: 836 PGLHGIPGEKGDPGPPGLDVP--GPPGERGSPGIPGAPGP-IGPPGSPGLPG-------- 884
Query: 1320 EWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD 1379
+ + T G P P P +G PG G VPG+ +GD
Sbjct: 885 --KAGASGFPGTKGEMGMMGPPGP----PGPLGIPGRSG---VPGL----KGD------- 924
Query: 1380 LSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGP---------GGRTGPG---- 1426
G++ Q PGP G+ GS G G GP G + PG
Sbjct: 925 ----------DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGI 974
Query: 1427 ---RGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQL 1483
G K P + +P PGLP PP P + + +I P G++ + +
Sbjct: 975 PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI--GPPGLKGTIGDM 1032
Query: 1484 S--SRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFE-EPGPMV 1540
QG PG P PG P +P P + + +P + GL P + EPG +
Sbjct: 1033 GFPGPQGVEGPPG--PSGVPGQPGSPGLPGQK-GDKGDPGISSIGLPGLPGPKGEPG--L 1087
Query: 1541 RGVGGTP--RDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAES 1598
G G P + S G P P P + LP GF G+ P PGP+ S
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGL-----PGTPGAKGQPGLP-----GFPGT-PGPPGPKGIS 1136
Query: 1599 RDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFED-VAGTEMSQSDSGVDLSG 1657
G L P P E P +D + G + + G G
Sbjct: 1137 GPPGNPGLPG------EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190
Query: 1658 DSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDG 1717
+ P DGGL G P PG P G PG + P PP +P G
Sbjct: 1191 NPGPPGLPGLSGQKGDGGLPGI----PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP--G 1244
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPG 1757
E P+ P P GP G R PGP P PG
Sbjct: 1245 PALEGPKGNPGPQGPPG--------RPGLPGPEGPPGLPG 1276
Score = 111 bits (278), Expect = 7e-24
Identities = 329/1418 (23%), Positives = 432/1418 (30%), Gaps = 320/1418 (22%)
Query: 237 PSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFP--------RVAGP 288
P G P +P G+ P P P GP GP P GP P GP
Sbjct: 169 PKGNPGYPGPPGIQG---LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGP 225
Query: 289 RGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGR 348
+G L P G P + E + D Q+ D G G ++ G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQK-RPIDVEFQKGDQGLPGDRGPPG-PPGIRGPPGPPGG 283
Query: 349 DSDEEGAEGHRDSQSASGEERP------------------PEADGKKGNSPNSEPPTP-- 388
+ E+G +G + G++ P DG+KG ++ PP P
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343
Query: 389 ----------------------------KTAWAETSRPPETEPGPPA------PKPPLPP 414
+ + PP PGPP P PP P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL-PGPPGAAVMGPPGPPGFP 402
Query: 415 PHRGPAGNWGPPG----DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRR 470
RG G+ GPPG P G P P P A S EI
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA--GPHIPPSDEICEPGPPGPPG 460
Query: 471 REEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAV------ 524
++ E+ K + D F + P P P P PP ++
Sbjct: 461 SPGDKGLQGEQ-----GVKGDKGDTCFNCIGTGISG-PPGQPGLPGLPGPPGSLGFPGQK 514
Query: 525 ----------PKELPAPPAPPPASA-PTPETEPEE------------PAQAPPAQSTP-- 559
PK LP P P A P + EP + +P A P
Sbjct: 515 GEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574
Query: 560 --TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVE 617
TPG P L G + P P LP G P PP PP P E
Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMG-PPGFGPPGPVGE 633
Query: 618 ---------PKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQ--QQHQWQQ 666
P GI + P Q + P + LP R L
Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692
Query: 667 HQQGSAPPTPVP----PSPPQPVTLGAVPAPQAPP----------PPPKALYPGALGRP- 711
GS +P P PP P +P P P PP +PG G P
Sbjct: 693 GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752
Query: 712 -----PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSS 766
PP PP + + P R G P PPG +P + D G +
Sbjct: 753 FALPGPPGPPGLPGFKGALGPK--GDRGFPGPPG----PPGRTGLDGLPGPKGDVGPNGQ 806
Query: 767 EPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETP 826
P + G P + P P + P+ Q G + +
Sbjct: 807 -------PGPMGPPGLPGIG----------VQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849
Query: 827 P----VPPPPPYLASYPGFPENGAPGP-------------PISRFP--LEEPGPRPLPWP 867
P VP PP S PG P GAPGP S FP E G P P
Sbjct: 850 PPGLDVPGPPGERGS-PGIP--GAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906
Query: 868 PGSDEV-AKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRW 926
PG + + P K + + L GP G K ++G G GPP P + ++
Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGP-TGEKGSKG-EPGLPGPPGPMDPNLLGSK- 963
Query: 927 GPRPGSSRRGIP-----------PEEPGAPPRRAGP-IKKPPPPTKVEELPPKPLEQGDE 974
G + GIP P +PG P P + PP P LP +P G
Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG-- 1021
Query: 975 TPKPPKPDPLKITKGKLG--GPK--ETPPNGNLSP----APRL------RRDYSYERVGP 1020
P LK T G +G GP+ E PP + P +P L + D +G
Sbjct: 1022 ------PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075
Query: 1021 TSCRGRGRGE----YFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHP 1076
G +GE + G +G+ G G +G G G G P P
Sbjct: 1076 PGLPG-PKGEPGLPGYPGNPGIKGSVGDPGLPG----LPGTPGAKGQPGLPGFPGTPG-P 1129
Query: 1077 PAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVP 1136
P P+G + + G E P G H P ++ ++G
Sbjct: 1130 PGPKG-ISGPPGNPGLPGEPGP---------VGGGGHPGQPGPPGEKGKPGQDG------ 1173
Query: 1137 LAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG-----------GRPPPQVCPGW 1185
P P G P F G P G+P G+ G G P P+ PG+
Sbjct: 1174 -IPGPAGQKGEPGQPGFGNPG-----PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGF 1227
Query: 1186 SPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRH 1245
P PP P P + P K PGP P R G G G +
Sbjct: 1228 HGFPGVQGPPGPPGSPGPALEGP---KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEK 1284
Query: 1246 GRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAK 1305
G Q P + +G+ G+P L PG + P K
Sbjct: 1285 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG---------LPGVPGFPGMK 1335
Query: 1306 SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGI 1365
P ++ E P +G PG G G
Sbjct: 1336 GPSGVPGSAGPEGE----------------------------PGLIGPPGPPGLPGPSGQ 1367
Query: 1366 SAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG- 1424
S + +GD + + PG + PGP G G G + G G GGR G
Sbjct: 1368 SIIIKGDAG--PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1425
Query: 1425 PGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAV 1462
PG + P + PP P GL PP PP +S+V
Sbjct: 1426 PGLPGQ---PGTRGLDGPP--GPDGLQGPPGPPGTSSV 1458
Score = 99.0 bits (245), Expect = 4e-20
Identities = 325/1337 (24%), Positives = 414/1337 (30%), Gaps = 308/1337 (23%)
Query: 512 PAAPSTPAP--PPAVPKE-----LPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
P P P P PP + +P PP P P P P PG
Sbjct: 59 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP-----PGLPGFPGTPGLPGMPGHD 113
Query: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG 624
AP G + F P P P +GP P P P K EP G I
Sbjct: 114 GAPGPQGIPGCNGTKGERGF---PGSPGFPGLQGP------PGPPGIPGMKGEP-GSIIM 163
Query: 625 PTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT--PVPPSPP 682
+ P GYP PP Q G PT P P PP
Sbjct: 164 SSLPGPKGNPGYPG-----PPGIQ---------------------GLPGPTGIPGPIGPP 197
Query: 683 QPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLD 742
P L P P P P G +G P + + PP ++ + + P+D
Sbjct: 198 GPPGLMGPPGPPGLPGPK-----GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252
Query: 743 FY----------------PPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVD 786
PPG+ P G EP R P E G P +
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312
Query: 787 PKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPEN-- 844
P +P P R + +KG + +T P P PP + PG
Sbjct: 313 -----------GLPGDPGYPGEPGR----DGEKGQKGDTGP-PGPPGLVIPRPGTGITIG 356
Query: 845 -----GAPGPPISRFPLEEPG---PRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGP 896
G PG P + PG P LP PPG A + PP P E
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG----AAVMGPPGPPGFPGER------- 405
Query: 897 EAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPP 956
G+K G +GPP GP PG + P PG PP AGP PP
Sbjct: 406 --GQK-------GDEGPPGISIP-------GP-PGLDGQPGAPGLPG-PPGPAGP-HIPP 446
Query: 957 PPTKVEELPPKPLE-------QGDETPKPPKPDPLKITKGK-LGGPKETP-------PNG 1001
E PP P QG++ K K D G + GP P P G
Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506
Query: 1002 NLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREF 1060
+L P + + + G T +G GF G+ G G + ++
Sbjct: 507 SLGFPGQKGEKG----QAGATGPKGLPGIPGAPGAPGFPGSKGEPG------DILTFPGM 556
Query: 1061 RGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEE-IPKRRRQRGSETGSETHESDLAP 1119
+GD G G G P P P G+ ++ +P +G E G T + + P
Sbjct: 557 KGDKGELGSPGAPGLPGLP-----------GTPGQDGLPGLPGPKG-EPGGITFKGERGP 604
Query: 1120 SDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG----- 1174
G + P+ PP G P G P G+P +G G
Sbjct: 605 PGNPGLPGLPGNIG--PMGPPGFGPPGPVGEKGIQGVAGNPGQP-GIPGPKGDPGQTITQ 661
Query: 1175 -GRPPPQVCPGWSP----PAKSLAPKKPPTGPLPPSK-EPLKEKL-IPGPLSPVARGGSN 1227
G+P PG P P +P +P SK EP + +PGP P G
Sbjct: 662 PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721
Query: 1228 GGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPE 1287
G G G PP F K E A G G P L A GP+
Sbjct: 722 GPPGAPGTPGRIGLEGPPG-------PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774
Query: 1288 EALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLT 1347
P R L D PP +
Sbjct: 775 GDRGFPGPPGPPGRTGLDG--LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI--- 829
Query: 1348 PKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGS 1407
P +G PG G +PG +GD D+ PGP G+ GS
Sbjct: 830 PGPIGQPGLHG---IPG----EKGDPGPPGLDV------------------PGPPGERGS 864
Query: 1408 SGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLD 1466
G G GP G G PG+ +P K PPG P P P S V L
Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG--PPGPPGPLGIPGRSGVPGL- 921
Query: 1467 QVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK--PGLPQAPQGPSPRPPTRYEPQRVN 1524
G+Q Q + P G K PGLP P GP + ++
Sbjct: 922 ----KGDDGLQG--------QPGLPGPTGEKGSKGEPGLP-GPPGPMDPNLLGSKGEKGE 968
Query: 1525 SGLSSDPHFEEPGPMVRGVGGTPRDSA--GVS-----PFPPKRRERP--PRKPELLQEES 1575
GL P P +G G P D G+S P PP + P P +P L+
Sbjct: 969 PGLPGIPGVSGP----KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG--- 1021
Query: 1576 LPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPL 1635
PP G +G PGPQ G PS + +P
Sbjct: 1022 --PPGLKGTIGDMGF-PGPQGVEGPPG----------------------PSGVPG--QPG 1054
Query: 1636 SPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSP----DGGLKGAAEGPPKRPGGSS 1691
SP + G + + D G+ G + GP + P + G+KG+ G P PG
Sbjct: 1055 SP--GLPGQKGDKGDPGISSIGLPGLP-GPKGEPGLPGYPGNPGIKGSV-GDPGLPG--- 1107
Query: 1692 PLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQ-RTDRGTEPGPI 1750
G PG++ P P P PPGP G EPGP+
Sbjct: 1108 ------LPGTPGAKGQPGLPGFPGT----------PGPPGPKGISGPPGNPGLPGEPGPV 1151
Query: 1751 RPSHRPGPPVQFGTSDK 1767
PG P G K
Sbjct: 1152 GGGGHPGQPGPPGEKGK 1168
Score = 84.7 bits (208), Expect = 9e-16
Identities = 198/822 (24%), Positives = 255/822 (31%), Gaps = 183/822 (22%)
Query: 1058 REFRGDDGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHES 1115
R F G +G G G GP PP PRG + G +
Sbjct: 50 RGFPGLEGHPGLPGFPGPEGPPGPRG-------------------------QKGDDGIPG 84
Query: 1116 DLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG- 1174
P P G P P PG +P P G RG P G G
Sbjct: 85 PPGPKGIRGPPGLPG-FPGTPGLPGMPGHDGAPGPQGIPGCNG-TKGERGFPGSPGFPGL 142
Query: 1175 -GRPPPQVCPGWSPPAKSL------APKKPPTGPLPPSKEPLKEKL-IPGPLSPVARGG- 1225
G P P PG S+ PK P P PP + L IPGP+ P G
Sbjct: 143 QGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202
Query: 1226 -------------SNGGSNVGMEDGERPRRRRH------GRAQQQDKPPRFRRLKQERE- 1265
N G N GE+ + G+ +Q +P K ++
Sbjct: 203 MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262
Query: 1266 NAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQN-SDQANEEWETA 1324
RG G P + P PG E+ P R K + +
Sbjct: 263 PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG 322
Query: 1325 SESSDFTSERRGDKEAP-PPVLLTPK-----AVGTPGGGGGGAVPGISAMSRGDLSQRAK 1378
D ++GD P PP L+ P+ +G G G +PG
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPG-------------- 368
Query: 1379 DLSKRSFSSQRPGMERQNRRPGPGGKA--------GSSGSSSGGGGGGPGGRTGPGRGDK 1430
+ +R F PG++ PGP G A G G G GP G + PG
Sbjct: 369 EKGERGF----PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424
Query: 1431 RSWPSPKNRSRPPEERPPGLPL--------PPPPPSS-----------------SAVFRL 1465
P PP P +P PP PP S F
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484
Query: 1466 DQVIHSNPAGIQQALAQLSSRQGSVTAPGGH----------PRHKPGLPQAPQGPSPRPP 1515
S P G Q L L GS+ PG P+ PG+P AP P P
Sbjct: 485 IGTGISGPPG-QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG-FPG 542
Query: 1516 TRYEPQRVNS--GLSSDP-HFEEPG-PMVRGVGGTP-RDSAGVSPFPP--------KRRE 1562
++ EP + + G+ D PG P + G+ GTP +D P P K
Sbjct: 543 SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602
Query: 1563 RPPRKPEL---------LQEESLPPPHSSGFLG--------SKPEGPGPQAESRDTGTEA 1605
PP P L + PP G G +P PGP+ + T T+
Sbjct: 603 GPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQP 662
Query: 1606 LTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGP 1665
P L R +P + + G++ G+ L G P
Sbjct: 663 GKP----GLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFP 718
Query: 1666 CSQRSSPDGGLKG--AAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKEL- 1722
G G EGPP PG P +G PG P P P G + L
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGP------KGEPGFALPGPPGPPGLPGFKGALG 772
Query: 1723 ---PREQPLPPGPIGTERSQRTDRGTEPGP---IRPSHRPGP 1758
R P PPGP G RT PGP + P+ +PGP
Sbjct: 773 PKGDRGFPGPPGPPG-----RTGLDGLPGPKGDVGPNGQPGP 809
Score = 81.3 bits (199), Expect = 1e-14
Identities = 225/953 (23%), Positives = 302/953 (31%), Gaps = 180/953 (18%)
Query: 105 PPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSR 164
PP + LP P + P PP P+ G++ A G G G +++
Sbjct: 604 PPGNPGLPG--LPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661
Query: 165 FSREEFPTLQAAGDQDKAAKERESAEQSSG----PGPSLRPQNSTTWRDG--GGRGPDEL 218
+ P D D G PG P G G +G +
Sbjct: 662 PGKPGLPG-NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 720
Query: 219 EGPDSKLHHGHDPRGGLQ-PSGPPQFPPYRG----MMPPFMYPPYLP-FPPPYGPQGPYR 272
GP G R GL+ P GPP FP +G +P PP LP F GP+G
Sbjct: 721 PGPPGA--PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRG 778
Query: 273 YPTPDGP---SRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGA 329
+P P GP + + GP+G V P G+P + L G G
Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGD------VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGP 832
Query: 330 HEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDS---QSASGEERPPEADGKKGNSPNSEPP 386
+ + D G G R S A G PP + G G + S P
Sbjct: 833 IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFP 892
Query: 387 TPKTAWAETSRPPETEPGPPAPKPPLPPPHR-------------GPAGNWGPPGDYPDRG 433
K GPP P PL P R G G GP G+ +G
Sbjct: 893 GTKGEMGMM--------GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944
Query: 434 GPPCK-PPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKR 492
P PP P D + + E+ E + + + +
Sbjct: 945 EPGLPGPPGPMDPN-------------------LLGSKGEKGEPGLPGIPGVSGPKGYQG 985
Query: 493 LDEKFGAPDKRLKAEPAAP--------PAAPSTPA--PPPAV-----------PKELPAP 531
L G P L +P P P P P PP + P+ + P
Sbjct: 986 LPGDPGQPG--LSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043
Query: 532 PAPP--PASAPTPETEPEEPAQAPPAQST----PTPGVAAAPTLVSGGGSTSSTSSGSFE 585
P P P +P ++ + P S+ PG P L G+ S
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103
Query: 586 ASPVEPQLPSKEGPEPPEEVPPPTTPPVPK--VEPKGDGIGPTRQPPSQGLGYPKYQKSL 643
P P P +G P PP PK P G+ P P G G+P +
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP--GQPG 1161
Query: 644 PPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTP--VPPSPPQPVTLGAVPAPQAPPPPPK 701
PP + + + + + + Q G P P +P Q G P P P
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221
Query: 702 ALYPGALGRP----PPMPPMNFDPRWMMIPPYVDPRLLQGRP--PLDFYPPGVHPSGLVP 755
PG G P PP PP + P P+ GRP P PPG+ +G +
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIK 1281
Query: 756 RERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAAD 815
E+ G+ +P P + ++G P + P P
Sbjct: 1282 GEK----GNPGQPGLPGLPGLKGDQGPPGLQ-----------GNPGRP------------ 1314
Query: 816 EDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEE------PGPRPLPWPP 868
GM+ + P L PGFP G G P S P E PGP LP P
Sbjct: 1315 -GLNGMKGD--------PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1365
Query: 869 GSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGP 928
G + K PP P + L GP+ G QG P P GP
Sbjct: 1366 GQSIIIKGDAGPP-GIPGQPGLKGLPGPQ-----------GPQGLPGPT---------GP 1404
Query: 929 RPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKP 981
R G+P + GA R+ P P T+ + PP P D PP P
Sbjct: 1405 PGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPPGP----DGLQGPPGP 1452
Score = 53.9 bits (128), Expect = 2e-06
Identities = 161/701 (22%), Positives = 207/701 (29%), Gaps = 134/701 (19%)
Query: 91 EQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHG 150
E+ DP PP + P P + P PP +P G+ A AS G
Sbjct: 844 EKGDPGPPGLDVPGPPGERGSPG--IPGAPGPIGPPGSP--------GLPGKAGASGFPG 893
Query: 151 AHGDGGRAS-----SLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNST 205
G+ G L R P L+ GD Q PGP+
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPGRSGVPGLK--GDDGLQG-------QPGLPGPT------- 937
Query: 206 TWRDGGGRGPDELEGPDSKLHHGHDPR--GGLQPSGPPQFPPYRGMMPPFMYPPYLPFPP 263
+ G +G L GP + DP G G P P G+ P Y P
Sbjct: 938 --GEKGSKGEPGLPGPPGPM----DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG 991
Query: 264 PYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQEND 323
G G P P GP P + G G P L +G + E
Sbjct: 992 QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV--------EGP 1043
Query: 324 DGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNS 383
G +G + ++ G G + G P G KG+
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV--G 1101
Query: 384 EPPTPKTAWAETSRPPETEPG-PPAPKPPLPPPHRGPAGNWGPPGD--------YPDRGG 434
+P P ++ PG P P PP P GP GN G PG+ +P + G
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161
Query: 435 PPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLD 494
PP + P + +K + + L +
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFG--------NPGPPGLPGLSGQKGDGGLPGIP 1213
Query: 495 EKFGAPDKRLKAEPA--------APPAAPSTPAPPPAVPKELPAPPAPP-PASAPTPETE 545
G P K EP PP P +P P PK P P PP P PE
Sbjct: 1214 GNPGLPGP--KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGP 1271
Query: 546 PEEPAQAPPAQSTPTPGVAAAPTL--VSGG-------GSTSSTSSGSFEASPVEPQLPSK 596
P P PG P L + G G+ + P P +P
Sbjct: 1272 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1331
Query: 597 EGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLL 656
G + P VP P E + IGP P GL P Q +
Sbjct: 1332 PGMKGPSGVPGSAGP-----EGEPGLIGP---PGPPGLPGPSGQSII------------- 1370
Query: 657 KQQQQHQWQQHQQGSAPPTPVPPSP-----PQPVTLGAVPAPQAPPPPPKAL----YPGA 707
+G A P +P P P P +P P PP P + GA
Sbjct: 1371 -----------IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1419
Query: 708 LGRP-PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747
GR P P R + PP P LQG P PPG
Sbjct: 1420 GGRKGDPGLPGQPGTRGLDGPP--GPDGLQGPPG----PPG 1454
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 129 bits (325), Expect = 2e-29
Identities = 334/1326 (25%), Positives = 439/1326 (33%), Gaps = 274/1326 (20%)
Query: 536 PASAPTPETEPEEPAQAPPAQSTPT-------PGVAAAPTLVSGGGSTSSTSSGSFEASP 588
P S P E P PA+ +++ G P +V G + A
Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464
Query: 589 VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP-KY--QKSLPP 645
+ P P +GP P P PP P DG+ PP L P +Y S P
Sbjct: 465 MGP--PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTMLMLPFRYGGDGSKGP 519
Query: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAV-----PAPQAPP--- 697
Q+ + QQ + G T P P + GA P PQ P
Sbjct: 520 TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 579
Query: 698 -PPPKALYPGALGRP--------PPMPPMNFDPRWMMIPPYVDPRLLQG-RPPLDFYPPG 747
PP PG GRP P P D + +P + +G R P PPG
Sbjct: 580 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG--PPG 637
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP--PVDPKLAWV-GDVFTATPAEPR 804
P R G P + +L RGTP P P +A V G P+
Sbjct: 638 P-PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696
Query: 805 PLTSPLRQAADEDDKGMRSETPPVPPP-------PPYLASYPGFP-------------EN 844
P Q + +G+ P+ PP P LA PG E
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 756
Query: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR 904
GA GPP + P+ PGPR + G+D V ++ K E ++ G + G K R
Sbjct: 757 GALGPPGPQGPIGYPGPRGVK---GADGVRGLKGS--KGEKGEDGFPGFKG-DMGLKGDR 810
Query: 905 G-VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEE 963
G VG G PR E GP R G P +PG P +AG K P
Sbjct: 811 GEVGQIG-----PRGED------GPEGPKGRAG-PTGDPG-PSGQAGEKGKLGVPG---- 853
Query: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-------PAPRLRRDYSYE 1016
LP P QG KG G P NG P PR +R
Sbjct: 854 LPGYPGRQGP--------------KGSTGFPGFPGANGEKGARGVAGKPGPRGQR----- 894
Query: 1017 RVGPTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GP 1073
GPT RG RG G+ G +GT GG G E RG G G G GP
Sbjct: 895 --GPTGPRG-SRGARGPTGKPGPKGTSGGDGPPGPPGE-------RGPQGPQGPVGFPGP 944
Query: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSD---KEAPTPKEG 1130
PP P G+ + +P QRG ETG + P + PT + G
Sbjct: 945 KGPPGPPGK------------DGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETG 991
Query: 1131 TLTQV--PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWS 1186
+ + P P PPG P A G P+G+ + G G G P + PG +
Sbjct: 992 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP-GPQGISGKDGPAGLRGFPGERGLPG-A 1049
Query: 1187 PPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRRRH 1245
A L + P GP PGP+ SP RG + +G+
Sbjct: 1050 QGAPGLKGGEGPQGP-------------PGPVGSPGERGSAGTAGPIGLP---------- 1086
Query: 1246 GRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAK 1305
GR Q P E +G G+ + P PGP A
Sbjct: 1087 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA--------------GPAG 1132
Query: 1306 SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPG 1364
SP + ++ E + +G+ P PP L P VG PG GG PG
Sbjct: 1133 SPG-------EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGDGEPG 1183
Query: 1365 ISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG 1424
+G Q+ D R F PG PGP G+ G +G G GP G G
Sbjct: 1184 PRGQ-QGMFGQKG-DEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240
Query: 1425 PGRGDKRSWP-----SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQA 1479
P + P S + E+ PG P PP + V P G +
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV--------GGPKGERGE 1292
Query: 1480 LAQLSSRQGSVTAPGGH-------PRHKPG---LPQAPQGPSPRPPTRYEPQRVNSGLSS 1529
+ + G+ PG P+ PG P P P P + + G
Sbjct: 1293 KGE-AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1351
Query: 1530 DPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP---------RKPELLQEESLPPPH 1580
DP +PGP P AG P PP +R P K + + PP
Sbjct: 1352 DPG--QPGPP------GPSGEAG-PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1402
Query: 1581 SSGFLGSKPEGP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFE 1639
+G P GP GP + G + + + + + P M P L +
Sbjct: 1403 KTG-----PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLK 1455
Query: 1640 DVAGTEMSQSDSGV----------DLSGDSQVSSGPCSQRSSPDGGLKGAA-----EGPP 1684
G++ + G+ GD + S + DGG+ G A GPP
Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515
Query: 1685 KRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPG----PIGTERSQR 1740
PG P GP G + P P P PPG P+ S++
Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----------GSPGPPGEVIQPLPILSSKK 1565
Query: 1741 TDRGTE 1746
T R TE
Sbjct: 1566 TRRHTE 1571
Score = 119 bits (298), Expect = 3e-26
Identities = 283/1165 (24%), Positives = 368/1165 (31%), Gaps = 285/1165 (24%)
Query: 678 PPSPPQPVTLGAVPA---PQAPP-------PPPKALYPGALGRPPPMPPMNFDPRWMMIP 727
PP P P + P P PP PP + PGA G P P M +M+P
Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM------LMLP 508
Query: 728 ----------PYVDPRLLQGRPPLDFY------PPGVHPSGLVPRERSDSGGSSSEPFDR 771
P + + Q + L PPG P GL R G SS
Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG--PMGLTGRPGPVGGPGSS----- 561
Query: 772 HAPAMLRERGTP-PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
E G P P P+ P P P ++ D G P
Sbjct: 562 ---GAKGESGDPGPQGPR---------GVQGPPGPTGKPGKRGRPGADGGRGM------P 603
Query: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEV-AKIQTPPPKKEPPKEE 889
P GF +G PG P + E GP+ P PPG D + + P+ P +
Sbjct: 604 GEPGAKGDRGF--DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 661
Query: 890 TAQLTGPEAGR-KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSR----RGIP-PEEPG 943
L GP P + +G GPP P+ + GP PG +G+P P+ P
Sbjct: 662 PRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLPGPQGPI 720
Query: 944 APPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNL 1003
PP GP KP + LP D P P + KG LG P P G
Sbjct: 721 GPPGEKGPQGKPG----LAGLPG-----ADGPPGHPGKEGQSGEKGALGPPGPQGPIGY- 770
Query: 1004 SPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGD 1063
P PR + R G +G + F +G G G RG + RG+
Sbjct: 771 -PGPRGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP-------RGE 821
Query: 1064 DGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS-----------ETGS 1110
DG G G GP P P G+ + + P R+ +GS E G+
Sbjct: 822 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 881
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRR 1170
P + PT G+ A P G P P + G P G P R
Sbjct: 882 RGVAGKPGPRGQRGPTGPRGSRG----ARGPTG---KPGPKGTSGGDG----PPGPPGER 930
Query: 1171 GRGG-----GRPPPQVCPGWSPPAKSLAPKKPP-------------------TGPLPPSK 1206
G G G P P+ PG PP K P P GP P+
Sbjct: 931 GPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 988
Query: 1207 E--PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264
E P+ E+ PGP P G G + G+ + G+ D P R ER
Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----DGPAGLRGFPGER 1044
Query: 1265 -------ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA 1317
+G EG P +PG + T P R + P A
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP------GPA 1098
Query: 1318 NEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRA 1377
E+ + + R G VG PG G PG +G++ +
Sbjct: 1099 GEKGAPGEKGPQGPAGRDG----------VQGPVGLPGPAGPAGSPGEDG-DKGEIGEPG 1147
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSS-GGGGGGPGGRTGPGRGDKRSWPSP 1436
+ SK G + +N PGP G G G+ GG G PG R G ++
Sbjct: 1148 QKGSK--------GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199
Query: 1437 KNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH 1496
+ PP P GL P PP G V G
Sbjct: 1200 RGFPGPPG--PIGLQGLPGPPGEKG------------------------ENGDVGPMG-- 1231
Query: 1497 PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPF 1556
P PG P+ PQGP+ + P V S V GVG +P
Sbjct: 1232 PPGPPG-PRGPQGPNGADGPQGPPGSVGS--------------VGGVGEKGEPGEAGNPG 1276
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSK--PEGPGPQAESRDTGTEALTPHIWNRL 1614
PP K E ++ PP ++G G+K P GP+ G
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF----------- 1325
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
P P EP GP Q G
Sbjct: 1326 ----------PGDPGPPGEP-----------------------------GPAGQDGV--G 1344
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
G KG +G P +PG P GPPG P P A +G + E G G
Sbjct: 1345 GDKGE-DGDPGQPGPPGPSGEAGPPGPPGKRGP--PGAAGAEGRQGE--------KGAKG 1393
Query: 1735 TERSQRTDRGTEP-GPIRPSHRPGP 1758
++ T P GP P+ +PGP
Sbjct: 1394 EAGAEGPPGKTGPVGPQGPAGKPGP 1418
Score = 111 bits (278), Expect = 7e-24
Identities = 339/1367 (24%), Positives = 434/1367 (31%), Gaps = 275/1367 (20%)
Query: 296 RLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD--EE 353
R V P+ ++E +E+ L E+ D E+ Y K E DGRDSD +
Sbjct: 335 RHVSGTNEPNPVEEIFTEEY--LTGEDYDSQRKNSEDTLYENK-----EIDGRDSDLLVD 387
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKT--------AWAETSR---PPETE 402
G G D E P + + P T T A+ E + P E
Sbjct: 388 GDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE 447
Query: 403 PGPPAPKPPLPPPHRGPAGNW---------GPPGDYPDRGGPPCKPPAPEDEDEAWRQRR 453
PG PP P GPAG GPPGD DR GPP +P P +
Sbjct: 448 PGMLVEGPPGPA---GPAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADG-----LP 498
Query: 454 KQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPA 513
+ + L + QE + A ++ + P P
Sbjct: 499 GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA-----------RIALRGPPGPMG 547
Query: 514 APSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEP--AQAPPAQSTPTPGVAAAPTLVS 571
P P P A + + P+ P Q PP T PG P
Sbjct: 548 LTGRPGP--------VGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADG 598
Query: 572 GGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG-IGPTRQPP 630
G G + P LP +G P PP DG IGP P
Sbjct: 599 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658
Query: 631 SQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLG-- 688
G PR G P P +P QP G
Sbjct: 659 EAG-----------PR-----------------------GLLGPRGTPGAPGQPGMAGVD 684
Query: 689 AVPAPQA-------PPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
P P+ P PP + PG G P P P+ PP + QG+P L
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG--------PP--GEKGPQGKPGL 734
Query: 742 DFYPPGVHPSGLVPRE-RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
P P G +E +S G+ P + RG D G +
Sbjct: 735 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG-----SK 789
Query: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPG 860
E P D KG R E + P E+G GP P +PG
Sbjct: 790 GEKGEDGFP-GFKGDMGLKGDRGEVGQIGPR----------GEDGPEGPKGRAGPTGDPG 838
Query: 861 PRPLPWPPGSDEVAKIQTPP----PKKEPPKEETAQLTGPEA-GRKPARGVGS-----GG 910
P + E K+ P P ++ PK T P A G K ARGV G
Sbjct: 839 P-----SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 893
Query: 911 QGPPPPR--RESRTET-RWGPRPGSSRRGIPPEEPG--APPRRAGPI-----KKPPPPTK 960
+GP PR R +R T + GP+ G+S PP PG P GP+ K PP P
Sbjct: 894 RGPTGPRGSRGARGPTGKPGPK-GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 952
Query: 961 VEELPPKPLEQGDE----TPKPPKPDPLKITKGKLG-----------GPKETPPNGNLSP 1005
+ LP P ++G+ PP P + +G G GP P L
Sbjct: 953 KDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPG 1012
Query: 1006 A---PRLRRDYSYERV----GPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR 1058
A + D + + GP RG +G G GG G S
Sbjct: 1013 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1072
Query: 1059 EFRGDDGRGG-----GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETH 1113
E RG G G G GP PP P G +G+ E+ P+ R G
Sbjct: 1073 E-RGSAGTAGPIGLPGRPGPQGPPGPAG-------EKGAPGEKGPQGPAGRDGVQGPVGL 1124
Query: 1114 ESDLAPSDKEAPTPKEGTLTQV----------PLAPPPPGAPPSPAPARFTARGGRVFTP 1163
P+ +G + + PP P P A A G P
Sbjct: 1125 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1184
Query: 1164 RGVPSRRGRGG--------GRPPP---QVCPGWSPPAK-----SLAPKKPPTGPLPPSKE 1207
RG G+ G G P P Q PG PP + + P PP GP P +
Sbjct: 1185 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG--PPGEKGENGDVGPMGPP-GP-PGPRG 1240
Query: 1208 PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENA 1267
P GP P GS GG E GE G A P+ R ++ E
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG--PKGER-GEKGEAG 1297
Query: 1268 ARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASES 1327
G+ G P P GP+ V P P A ++ +
Sbjct: 1298 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---------AGQDGVGGDKG 1348
Query: 1328 SDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSS 1387
D GD P P + +A G PG G PG +A + G ++
Sbjct: 1349 ED------GDPGQPGPPGPSGEA-GPPGPPGKRGPPG-AAGAEGRQGEK----------- 1389
Query: 1388 QRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEER 1446
G + + GP GK G G G GP G G PG ++ P + PP
Sbjct: 1390 ---GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446
Query: 1447 -PPGLP-LPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--LSSRQGSVTAPGG------- 1495
PPGLP L P S + P G Q L QGS A G
Sbjct: 1447 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506
Query: 1496 ---HPRHKPGLPQAPQGP-SPRPPTRYEPQRVNSGLSSDPHFEEPGP 1538
P PGLP PQGP + T Q+ +SGL P PGP
Sbjct: 1507 GPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPP--GSPGP 1550
Score = 106 bits (264), Expect = 3e-22
Identities = 242/936 (25%), Positives = 303/936 (32%), Gaps = 197/936 (21%)
Query: 882 KKEPPKEETAQLT-GPEAGRKPARGVGSGG-QGPPPPRRESRTETRWGPRPGSSRRGIPP 939
K EP E L GP PA +G G QGP P + G R R G+P
Sbjct: 440 KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------GDRGPPGRPGLPG 493
Query: 940 EE--PGAP------PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKIT--KG 989
+ PG P P R G P +E + + Q P P+ +T G
Sbjct: 494 ADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 553
Query: 990 KLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
+GGP + G P P+ R GPT G+ GRG G G +G
Sbjct: 554 PVGGPGSSGAKGESGDPGPQGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGAKG-- 610
Query: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSET 1108
R F GD G G G P PP P G +G E+ E
Sbjct: 611 --DRGFDGLPGLPGDKGHRGERG-PQGPPGPPG-------DDGMRGED---------GEI 651
Query: 1109 GSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRV--FTPRGV 1166
G + P P GT PGAP P A G P+G
Sbjct: 652 GPRGLPGEAGPRGLLGP---RGT----------PGAPGQPGMAGVDGPPGPKGNMGPQGE 698
Query: 1167 PSRRGRGGGRPPPQVCPG----WSPPAKSLAPKKPPTGPLP--------PSKEPLK-EKL 1213
P G+ G P PQ PG PP + KP LP P KE EK
Sbjct: 699 PGPPGQQGN-PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 757
Query: 1214 IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEG 1273
GP P G G V DG R + G + +D P F+ + +G G
Sbjct: 758 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG-----DMGLKGDRG 811
Query: 1274 KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSE 1333
+ P GPE P+ A + D S QA E+ +
Sbjct: 812 EVGQIGPRGEDGPE----------GPKGRAGPTGDPGP--SGQAGEKGKLGVPGLPGYPG 859
Query: 1334 RRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGME 1393
R+G K + G PG G G++ G QR + S ++
Sbjct: 860 RQGPKGSTG-------FPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGAR----- 906
Query: 1394 RQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGP-GRGDKRSWPSPKNRSRPPEERPPGLPL 1452
GP GK G G+S G G GP G GP G +P PK PP + GLP
Sbjct: 907 ------GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK--DGLPG 958
Query: 1453 PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPS- 1511
P + QG PG PG PQGP+
Sbjct: 959 HPGQRGETGF------------------------QGKTGPPG------PGGVVGPQGPTG 988
Query: 1512 ----------PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRR 1561
P PP Q + + +PGP +G+ G AG+ FP +R
Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKD-GPAGLRGFPGER- 1044
Query: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRK 1621
P + G G K G GPQ G+ R T+
Sbjct: 1045 ---------------GLPGAQGAPGLK-GGEGPQGPPGPVGSPG------ERGSAGTAGP 1082
Query: 1622 SYRPSSMEPWMEPLSPFEDVA-GTEMSQSDSGVDLSGDSQVSSGPCSQRSSP--DG---- 1674
P P P E A G + Q +G D GP SP DG
Sbjct: 1083 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1142
Query: 1675 ----GLKGA-----AEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE 1725
G KG+ GPP PG P+ A G G EP R E R
Sbjct: 1143 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG-EPGPRGQQGMFGQKGDEGARG 1201
Query: 1726 QPLPPGPIGTE--RSQRTDRGTEPGPIRPSHRPGPP 1759
P PPGPIG + ++G E G + P PGPP
Sbjct: 1202 FPGPPGPIGLQGLPGPPGEKG-ENGDVGPMGPPGPP 1236
Score = 94.4 bits (233), Expect = 1e-18
Identities = 301/1240 (24%), Positives = 375/1240 (30%), Gaps = 280/1240 (22%)
Query: 105 PPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSR 164
P + P P P PP P + P G A G G G L R
Sbjct: 456 PGPAGPAGIMGPPGLQGPTGPPGDPGDRG--PPGRPGLPGAD---GLPGPPGTMLMLPFR 510
Query: 165 FSRE--EFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDG--GGRGPDELEG 220
+ + + PT+ A Q +A ++ PGP T R G GG G +G
Sbjct: 511 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM-----GLTGRPGPVGGPGSSGAKG 565
Query: 221 PDSKLHHGHDPRGGLQPSGPPQFPPYRGM--------MPP---------FMYPPYLPFPP 263
+S PRG P GP P RG MP F P LP
Sbjct: 566 -ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 624
Query: 264 PY----GPQGPYRYPTPDG---------PSRFPRVAGPRGSGPPMRLVEPVGRPSILKED 310
+ GPQGP P DG P P AGPRG L+ P G P
Sbjct: 625 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPG----- 673
Query: 311 NLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP 370
G AG +G G + + GE P
Sbjct: 674 ---------APGQPGMAGV-----------------------DGPPGPKGNMGPQGEPGP 701
Query: 371 PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL-PPPHRGPAGNWGPPGDY 429
P G++GN P P+ G P P+ P+ PP +GP G G G
Sbjct: 702 P---GQQGN------PGPQ--------------GLPGPQGPIGPPGEKGPQGKPGLAG-L 737
Query: 430 PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEK 489
P GPP P E I R + + R K
Sbjct: 738 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV--------RGLKGSK 789
Query: 490 LKRLDEKFGA--PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETE-- 545
++ ++ F D LK + P PK P P S E
Sbjct: 790 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849
Query: 546 -----PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
P P + P ST PG G+ + P GP
Sbjct: 850 GVPGLPGYPGRQGPKGSTGFPGFP---------GANGEKGARGVAGKPGPRGQRGPTGPR 900
Query: 601 PPEEVPPPTTPPVPKVEPKGDG-IGPTRQPPSQG----LGYPKYQKSLPPRFQRQQQEQL 655
PT P PK GDG GP + QG +G+P + P ++ L
Sbjct: 901 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP----PGKDGL 956
Query: 656 LKQQQQHQWQQHQQGSAPPTP---VPPSPPQPVT--LGAVPAPQAPPPPPKALYPGALGR 710
Q Q + PP P V P P T +G P P PP + PGA G+
Sbjct: 957 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016
Query: 711 PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-----PGVH-------PSGLV--PR 756
DP I P L+G P P PG+ P G V P
Sbjct: 1017 ----EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1072
Query: 757 ERSDSG-----GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
ER +G G P + P E+G P G P P
Sbjct: 1073 ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG 1132
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPL---------EEPGP- 861
++ DKG E P S ENG PGPP + P+ EPGP
Sbjct: 1133 SPGEDGDKGEIGE-------PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1185
Query: 862 --------------RPLPWPPGSDEVAKIQTPPPKK-EPPKEETAQLTGPEAGRKPARGV 906
R P PPG + + PP +K E GP R P
Sbjct: 1186 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1245
Query: 907 GSGG-QGPP---------PPRRESRTETRWGPRPGSSRRGIPPEEPG-----APPRRAGP 951
G+ G QGPP + E GP PG + G P E G PP AGP
Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGP 1304
Query: 952 IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
PP GD+ PK P P+ G G P E P G
Sbjct: 1305 PGAKGPP-------------GDDGPK-GNPGPVGF-PGDPGPPGEPGPAGQDGVGGDKGE 1349
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG--G 1069
D + GP G RG G G GR + + +G+ G G G
Sbjct: 1350 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR-------QGEKGAKGEAGAEGPPG 1402
Query: 1070 TGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKE 1129
GP P P G+ E IP ++G + ++ P
Sbjct: 1403 KTGPVGPQGPAGKPGPE------GLRGIPGPVGEQGLP----------GAAGQDGPPG-- 1444
Query: 1130 GTLTQVPLAPPP-PGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPP 1188
P+ PP PG P G + G P +G G R P SP
Sbjct: 1445 ------PMGPPGLPGLKGDPGSKGEKGHPGLIGL-IGPPGEQGEKGDRGLPGT--QGSPG 1495
Query: 1189 AKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG 1228
AK P GPL P P +PGP P GS G
Sbjct: 1496 AKGDGGIPGPAGPLGPPGPP----GLPGPQGPKGNKGSTG 1531
Score = 89.0 bits (219), Expect = 5e-17
Identities = 241/1007 (23%), Positives = 317/1007 (31%), Gaps = 220/1007 (21%)
Query: 211 GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL-------PFPP 263
G GP L GP + P G P G P G P +P P
Sbjct: 706 GNPGPQGLPGPQGPI----GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 761
Query: 264 PYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLK----EFDQLD 319
P GPQGP YP P G V G +GS G P + LK E Q+
Sbjct: 762 P-GPQGPIGYPGPRGVKGADGVRGLKGSKGEK---GEDGFPGFKGDMGLKGDRGEVGQIG 817
Query: 320 QENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP--------- 370
+DG G T D + E+G G G + P
Sbjct: 818 PRGEDGPEGPKGRAGPT-----GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 872
Query: 371 PEADGKKGNSPNSEPPTPKTAWAET-------SRPPETEPGPPAPK----PPLPPPHRGP 419
P A+G+KG + P P+ T +R P +PGP PP PP RGP
Sbjct: 873 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 932
Query: 420 AGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
G GP G +P GPP PP + QR +
Sbjct: 933 QGPQGPVG-FPGPKGPP-GPPGKDGLPGHPGQRGETG----------------------- 967
Query: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP---- 535
K G P P P T P + P PP PP
Sbjct: 968 -------------FQGKTGPPGPGGVVGPQGP-----TGETGPIGERGHPGPPGPPGEQG 1009
Query: 536 -PASAPTPETEPEEPAQAPPAQSTPT-----------PGVAAAPTLVSGGGSTSSTSSGS 583
P +A + + Q + P PG AP L G G
Sbjct: 1010 LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP-- 1067
Query: 584 FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG----IGPTRQPPSQG-LGYPK 638
SP E GP P P PP P E G GP + QG +G P
Sbjct: 1068 -VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP- 1125
Query: 639 YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP 698
+ P + ++ + + + +G P P PP PV + P
Sbjct: 1126 -GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-PGPPGLQGPVGAPGIAGGDGEPG 1183
Query: 699 P--PKALY-----PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPS 751
P + ++ GA G P P P+ + + PP P PPG P
Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPG--PR 1239
Query: 752 GLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
G P+ + + G P + + E+G P G+ P + P
Sbjct: 1240 G--PQGPNGADGPQGPPGSVGSVGGVGEKGEP---------GEAGNPGPPGEAGVGGPKG 1288
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGS 870
+ ++ + G PP PP PG G PGP FP +PGP P P G
Sbjct: 1289 ERGEKGEAG-----PPGAAGPPGAKGPPGDDGPKGNPGP--VGFP-GDPGPPGEPGPAGQ 1340
Query: 871 DEVA--KIQTPPPKKEPPKEETAQL--TGPEAGRKPARGVGS-GGQGPPPPRRESRTETR 925
D V K + P + P + + GP R P G+ G QG + E+ E
Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE-- 1398
Query: 926 WGPRPGSSRRGIPPEEPGAPPRRAGP--IKKPPPPTKVEELPPKPLEQGDETPKPPKPDP 983
GP PG + P P P + GP ++ P P + LP + G P P P
Sbjct: 1399 -GP-PGKT----GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PPGPMGPPG 1450
Query: 984 LKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYG 1043
L KG G E G + +GP +G +G+ RG GT G
Sbjct: 1451 LPGLKGDPGSKGEKGHPGLIG------------LIGPPGEQGE-KGD-----RGLPGTQG 1492
Query: 1044 GRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQ 1103
G +GD G G GP PP P G + PK +
Sbjct: 1493 SPGA-------------KGDGGI-PGPAGPLGPPGPPGLPGPQG----------PKGNKG 1528
Query: 1104 RGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAP 1150
G + D P P P +P PPG P P
Sbjct: 1529 STGPAGQK--------GDSGLPGP--------PGSPGPPGEVIQPLP 1559
Score = 72.4 bits (176), Expect = 4e-12
Identities = 188/782 (24%), Positives = 237/782 (30%), Gaps = 105/782 (13%)
Query: 136 PSGVKSWAQASVTHGAHGDGGRASSL----LSRFSREEFPTLQAAGDQDKAAKERESAEQ 191
P G K A + G G G L L + + P A + A
Sbjct: 824 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 883
Query: 192 SSG-PGPSLRPQNSTTWRDG--GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRG 248
+G PGP R Q T G G RGP GP GG P GPP +G
Sbjct: 884 VAGKPGP--RGQRGPTGPRGSRGARGPTGKPGPKGT-------SGGDGPPGPPGERGPQG 934
Query: 249 MMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILK 308
P +P P P G G +P G + F GP G G + P G +
Sbjct: 935 PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 994
Query: 309 EDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEE 368
E + G GA + E K G S ++G G R G
Sbjct: 995 ERG--HPGPPGPPGEQGLPGAAGK----EGAKGDPGPQG-ISGKDGPAGLRGFPGERGLP 1047
Query: 369 RPPEADGKKGNSPNSEPPTPKTAWAET----SRPPETEPGPPAPK-PPLPPPHRGPAGNW 423
A G KG PP P + E + P PG P P+ PP P +G G
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1107
Query: 424 GPPG-----------DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
GP G P GP P D+ E +K S + + E
Sbjct: 1108 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD----------KGE 1157
Query: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPP 532
+ A + D + G ++ A P PP P L P
Sbjct: 1158 NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG--PIGLQGLP 1215
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT-------LVSGGGSTSSTSSGSFE 585
PP + P P P + P A P V G G
Sbjct: 1216 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1275
Query: 586 ASPVEPQL--PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKS 642
P E + P E E E PP P P GD GP P G G P
Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD-GPKGNPGPVGFPGDPG---- 1330
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV----PPSPP----QPVTLGAVPAPQ 694
PP + + + Q G PP P PP PP P GA
Sbjct: 1331 -PPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1387
Query: 695 APPPPPKALYPGALGRPPPMPPM----NFDPRWMM-IPPYVDPRLLQGRPPLDFYPPGVH 749
+A G G+ P+ P P + IP V + L G D P +
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447
Query: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809
P GL P + D G E+G P + + +G R L
Sbjct: 1448 PPGL-PGLKGDPGSKG-------------EKGHPGL---IGLIGPPGEQGEKGDRGLPGT 1490
Query: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPP 868
+ D G+ P+ PP P PG P G G S P + G LP PP
Sbjct: 1491 QGSPGAKGDGGIPGPAGPLGPPGP-----PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1545
Query: 869 GS 870
GS
Sbjct: 1546 GS 1547
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/301 (24%), Positives = 96/301 (31%), Gaps = 58/301 (19%)
Query: 57 PPPANLPSLKAENKGNDPNVSLV----PKDGTGWASKQEQSDPKSSDASTAQPPESQPLP 112
PP A P KGN V P G A + K D QP P
Sbjct: 1304 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1363
Query: 113 ASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPT 172
+ P + PP A G + A GA G G+ +
Sbjct: 1364 EAGPPGPPGKRGPPGAAG-----AEGRQGEKGAKGEAGAEGPPGKTGPV----------- 1407
Query: 173 LQAAGDQDKAAKERESAEQSSGPGP-SLRPQNSTTWRDG--GGRGPDELEG----PDSKL 225
G Q A K + PGP + +DG G GP L G P SK
Sbjct: 1408 ----GPQGPAGKPGPEGLRGI-PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1462
Query: 226 HHGHDPRGGLQPSGPPQFPPYRGM--MPPFMYPPY------LPFPP-PYGPQGPYRYPTP 276
GH GL GPP +G +P P +P P P GP GP P P
Sbjct: 1463 EKGHPGLIGL--IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1520
Query: 277 DGPSRFPRVAGPRGS-------------GPPMRLVEPVGRPSILKEDNLKEFDQLDQEND 323
GP GP G GPP +++P+ P + + + + + + D
Sbjct: 1521 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL--PILSSKKTRRHTEGMQADAD 1578
Query: 324 D 324
D
Sbjct: 1579 D 1579
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 129 bits (325), Expect = 2e-29
Identities = 334/1326 (25%), Positives = 439/1326 (33%), Gaps = 274/1326 (20%)
Query: 536 PASAPTPETEPEEPAQAPPAQSTPT-------PGVAAAPTLVSGGGSTSSTSSGSFEASP 588
P S P E P PA+ +++ G P +V G + A
Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413
Query: 589 VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP-KY--QKSLPP 645
+ P P +GP P P PP P DG+ PP L P +Y S P
Sbjct: 414 MGP--PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTMLMLPFRYGGDGSKGP 468
Query: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAV-----PAPQAPP--- 697
Q+ + QQ + G T P P + GA P PQ P
Sbjct: 469 TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 528
Query: 698 -PPPKALYPGALGRP--------PPMPPMNFDPRWMMIPPYVDPRLLQG-RPPLDFYPPG 747
PP PG GRP P P D + +P + +G R P PPG
Sbjct: 529 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG--PPG 586
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP--PVDPKLAWV-GDVFTATPAEPR 804
P R G P + +L RGTP P P +A V G P+
Sbjct: 587 P-PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645
Query: 805 PLTSPLRQAADEDDKGMRSETPPVPPP-------PPYLASYPGFP-------------EN 844
P Q + +G+ P+ PP P LA PG E
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
Query: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR 904
GA GPP + P+ PGPR + G+D V ++ K E ++ G + G K R
Sbjct: 706 GALGPPGPQGPIGYPGPRGVK---GADGVRGLKGS--KGEKGEDGFPGFKG-DMGLKGDR 759
Query: 905 G-VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEE 963
G VG G PR E GP R G P +PG P +AG K P
Sbjct: 760 GEVGQIG-----PRGED------GPEGPKGRAG-PTGDPG-PSGQAGEKGKLGVPG---- 802
Query: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-------PAPRLRRDYSYE 1016
LP P QG KG G P NG P PR +R
Sbjct: 803 LPGYPGRQGP--------------KGSTGFPGFPGANGEKGARGVAGKPGPRGQR----- 843
Query: 1017 RVGPTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GP 1073
GPT RG RG G+ G +GT GG G E RG G G G GP
Sbjct: 844 --GPTGPRG-SRGARGPTGKPGPKGTSGGDGPPGPPGE-------RGPQGPQGPVGFPGP 893
Query: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSD---KEAPTPKEG 1130
PP P G+ + +P QRG ETG + P + PT + G
Sbjct: 894 KGPPGPPGK------------DGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETG 940
Query: 1131 TLTQV--PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWS 1186
+ + P P PPG P A G P+G+ + G G G P + PG +
Sbjct: 941 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP-GPQGISGKDGPAGLRGFPGERGLPG-A 998
Query: 1187 PPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRRRH 1245
A L + P GP PGP+ SP RG + +G+
Sbjct: 999 QGAPGLKGGEGPQGP-------------PGPVGSPGERGSAGTAGPIGLP---------- 1035
Query: 1246 GRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAK 1305
GR Q P E +G G+ + P PGP A
Sbjct: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA--------------GPAG 1081
Query: 1306 SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPG 1364
SP + ++ E + +G+ P PP L P VG PG GG PG
Sbjct: 1082 SPG-------EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGDGEPG 1132
Query: 1365 ISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG 1424
+G Q+ D R F PG PGP G+ G +G G GP G G
Sbjct: 1133 PRGQ-QGMFGQKG-DEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1189
Query: 1425 PGRGDKRSWP-----SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQA 1479
P + P S + E+ PG P PP + V P G +
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV--------GGPKGERGE 1241
Query: 1480 LAQLSSRQGSVTAPGGH-------PRHKPG---LPQAPQGPSPRPPTRYEPQRVNSGLSS 1529
+ + G+ PG P+ PG P P P P + + G
Sbjct: 1242 KGE-AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1300
Query: 1530 DPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP---------RKPELLQEESLPPPH 1580
DP +PGP P AG P PP +R P K + + PP
Sbjct: 1301 DPG--QPGPP------GPSGEAG-PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1351
Query: 1581 SSGFLGSKPEGP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFE 1639
+G P GP GP + G + + + + + P M P L +
Sbjct: 1352 KTG-----PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLK 1404
Query: 1640 DVAGTEMSQSDSGV----------DLSGDSQVSSGPCSQRSSPDGGLKGAA-----EGPP 1684
G++ + G+ GD + S + DGG+ G A GPP
Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464
Query: 1685 KRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPG----PIGTERSQR 1740
PG P GP G + P P P PPG P+ S++
Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----------GSPGPPGEVIQPLPILSSKK 1514
Query: 1741 TDRGTE 1746
T R TE
Sbjct: 1515 TRRHTE 1520
Score = 119 bits (298), Expect = 3e-26
Identities = 283/1165 (24%), Positives = 368/1165 (31%), Gaps = 285/1165 (24%)
Query: 678 PPSPPQPVTLGAVPA---PQAPP-------PPPKALYPGALGRPPPMPPMNFDPRWMMIP 727
PP P P + P P PP PP + PGA G P P M +M+P
Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM------LMLP 457
Query: 728 ----------PYVDPRLLQGRPPLDFY------PPGVHPSGLVPRERSDSGGSSSEPFDR 771
P + + Q + L PPG P GL R G SS
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG--PMGLTGRPGPVGGPGSS----- 510
Query: 772 HAPAMLRERGTP-PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
E G P P P+ P P P ++ D G P
Sbjct: 511 ---GAKGESGDPGPQGPR---------GVQGPPGPTGKPGKRGRPGADGGRGM------P 552
Query: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEV-AKIQTPPPKKEPPKEE 889
P GF +G PG P + E GP+ P PPG D + + P+ P +
Sbjct: 553 GEPGAKGDRGF--DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 610
Query: 890 TAQLTGPEAGR-KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSR----RGIP-PEEPG 943
L GP P + +G GPP P+ + GP PG +G+P P+ P
Sbjct: 611 PRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLPGPQGPI 669
Query: 944 APPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNL 1003
PP GP KP + LP D P P + KG LG P P G
Sbjct: 670 GPPGEKGPQGKPG----LAGLPG-----ADGPPGHPGKEGQSGEKGALGPPGPQGPIGY- 719
Query: 1004 SPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGD 1063
P PR + R G +G + F +G G G RG + RG+
Sbjct: 720 -PGPRGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP-------RGE 770
Query: 1064 DGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS-----------ETGS 1110
DG G G GP P P G+ + + P R+ +GS E G+
Sbjct: 771 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 830
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRR 1170
P + PT G+ A P G P P + G P G P R
Sbjct: 831 RGVAGKPGPRGQRGPTGPRGSRG----ARGPTG---KPGPKGTSGGDG----PPGPPGER 879
Query: 1171 GRGG-----GRPPPQVCPGWSPPAKSLAPKKPP-------------------TGPLPPSK 1206
G G G P P+ PG PP K P P GP P+
Sbjct: 880 GPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 937
Query: 1207 E--PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264
E P+ E+ PGP P G G + G+ + G+ D P R ER
Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----DGPAGLRGFPGER 993
Query: 1265 -------ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA 1317
+G EG P +PG + T P R + P A
Sbjct: 994 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP------GPA 1047
Query: 1318 NEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRA 1377
E+ + + R G VG PG G PG +G++ +
Sbjct: 1048 GEKGAPGEKGPQGPAGRDG----------VQGPVGLPGPAGPAGSPGEDG-DKGEIGEPG 1096
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSS-GGGGGGPGGRTGPGRGDKRSWPSP 1436
+ SK G + +N PGP G G G+ GG G PG R G ++
Sbjct: 1097 QKGSK--------GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148
Query: 1437 KNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH 1496
+ PP P GL P PP G V G
Sbjct: 1149 RGFPGPPG--PIGLQGLPGPPGEKG------------------------ENGDVGPMG-- 1180
Query: 1497 PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPF 1556
P PG P+ PQGP+ + P V S V GVG +P
Sbjct: 1181 PPGPPG-PRGPQGPNGADGPQGPPGSVGS--------------VGGVGEKGEPGEAGNPG 1225
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSK--PEGPGPQAESRDTGTEALTPHIWNRL 1614
PP K E ++ PP ++G G+K P GP+ G
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF----------- 1274
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
P P EP GP Q G
Sbjct: 1275 ----------PGDPGPPGEP-----------------------------GPAGQDGV--G 1293
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
G KG +G P +PG P GPPG P P A +G + E G G
Sbjct: 1294 GDKGE-DGDPGQPGPPGPSGEAGPPGPPGKRGP--PGAAGAEGRQGE--------KGAKG 1342
Query: 1735 TERSQRTDRGTEP-GPIRPSHRPGP 1758
++ T P GP P+ +PGP
Sbjct: 1343 EAGAEGPPGKTGPVGPQGPAGKPGP 1367
Score = 111 bits (278), Expect = 7e-24
Identities = 339/1367 (24%), Positives = 434/1367 (31%), Gaps = 275/1367 (20%)
Query: 296 RLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD--EE 353
R V P+ ++E +E+ L E+ D E+ Y K E DGRDSD +
Sbjct: 284 RHVSGTNEPNPVEEIFTEEY--LTGEDYDSQRKNSEDTLYENK-----EIDGRDSDLLVD 336
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKT--------AWAETSR---PPETE 402
G G D E P + + P T T A+ E + P E
Sbjct: 337 GDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE 396
Query: 403 PGPPAPKPPLPPPHRGPAGNW---------GPPGDYPDRGGPPCKPPAPEDEDEAWRQRR 453
PG PP P GPAG GPPGD DR GPP +P P +
Sbjct: 397 PGMLVEGPPGPA---GPAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADG-----LP 447
Query: 454 KQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPA 513
+ + L + QE + A ++ + P P
Sbjct: 448 GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA-----------RIALRGPPGPMG 496
Query: 514 APSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEP--AQAPPAQSTPTPGVAAAPTLVS 571
P P P A + + P+ P Q PP T PG P
Sbjct: 497 LTGRPGP--------VGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADG 547
Query: 572 GGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG-IGPTRQPP 630
G G + P LP +G P PP DG IGP P
Sbjct: 548 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 607
Query: 631 SQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLG-- 688
G PR G P P +P QP G
Sbjct: 608 EAG-----------PR-----------------------GLLGPRGTPGAPGQPGMAGVD 633
Query: 689 AVPAPQA-------PPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
P P+ P PP + PG G P P P+ PP + QG+P L
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG--------PP--GEKGPQGKPGL 683
Query: 742 DFYPPGVHPSGLVPRE-RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
P P G +E +S G+ P + RG D G +
Sbjct: 684 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG-----SK 738
Query: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPG 860
E P D KG R E + P E+G GP P +PG
Sbjct: 739 GEKGEDGFP-GFKGDMGLKGDRGEVGQIGPR----------GEDGPEGPKGRAGPTGDPG 787
Query: 861 PRPLPWPPGSDEVAKIQTPP----PKKEPPKEETAQLTGPEA-GRKPARGVGS-----GG 910
P + E K+ P P ++ PK T P A G K ARGV G
Sbjct: 788 P-----SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842
Query: 911 QGPPPPR--RESRTET-RWGPRPGSSRRGIPPEEPG--APPRRAGPI-----KKPPPPTK 960
+GP PR R +R T + GP+ G+S PP PG P GP+ K PP P
Sbjct: 843 RGPTGPRGSRGARGPTGKPGPK-GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901
Query: 961 VEELPPKPLEQGDE----TPKPPKPDPLKITKGKLG-----------GPKETPPNGNLSP 1005
+ LP P ++G+ PP P + +G G GP P L
Sbjct: 902 KDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPG 961
Query: 1006 A---PRLRRDYSYERV----GPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR 1058
A + D + + GP RG +G G GG G S
Sbjct: 962 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
Query: 1059 EFRGDDGRGG-----GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETH 1113
E RG G G G GP PP P G +G+ E+ P+ R G
Sbjct: 1022 E-RGSAGTAGPIGLPGRPGPQGPPGPAG-------EKGAPGEKGPQGPAGRDGVQGPVGL 1073
Query: 1114 ESDLAPSDKEAPTPKEGTLTQV----------PLAPPPPGAPPSPAPARFTARGGRVFTP 1163
P+ +G + + PP P P A A G P
Sbjct: 1074 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1133
Query: 1164 RGVPSRRGRGG--------GRPPP---QVCPGWSPPAK-----SLAPKKPPTGPLPPSKE 1207
RG G+ G G P P Q PG PP + + P PP GP P +
Sbjct: 1134 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG--PPGEKGENGDVGPMGPP-GP-PGPRG 1189
Query: 1208 PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENA 1267
P GP P GS GG E GE G A P+ R ++ E
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG--PKGER-GEKGEAG 1246
Query: 1268 ARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASES 1327
G+ G P P GP+ V P P A ++ +
Sbjct: 1247 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---------AGQDGVGGDKG 1297
Query: 1328 SDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSS 1387
D GD P P + +A G PG G PG +A + G ++
Sbjct: 1298 ED------GDPGQPGPPGPSGEA-GPPGPPGKRGPPG-AAGAEGRQGEK----------- 1338
Query: 1388 QRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEER 1446
G + + GP GK G G G GP G G PG ++ P + PP
Sbjct: 1339 ---GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395
Query: 1447 -PPGLP-LPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--LSSRQGSVTAPGG------- 1495
PPGLP L P S + P G Q L QGS A G
Sbjct: 1396 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455
Query: 1496 ---HPRHKPGLPQAPQGP-SPRPPTRYEPQRVNSGLSSDPHFEEPGP 1538
P PGLP PQGP + T Q+ +SGL P PGP
Sbjct: 1456 GPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPP--GSPGP 1499
Score = 106 bits (264), Expect = 3e-22
Identities = 242/936 (25%), Positives = 303/936 (32%), Gaps = 197/936 (21%)
Query: 882 KKEPPKEETAQLT-GPEAGRKPARGVGSGG-QGPPPPRRESRTETRWGPRPGSSRRGIPP 939
K EP E L GP PA +G G QGP P + G R R G+P
Sbjct: 389 KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------GDRGPPGRPGLPG 442
Query: 940 EE--PGAP------PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKIT--KG 989
+ PG P P R G P +E + + Q P P+ +T G
Sbjct: 443 ADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 502
Query: 990 KLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
+GGP + G P P+ R GPT G+ GRG G G +G
Sbjct: 503 PVGGPGSSGAKGESGDPGPQGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGAKG-- 559
Query: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSET 1108
R F GD G G G P PP P G +G E+ E
Sbjct: 560 --DRGFDGLPGLPGDKGHRGERG-PQGPPGPPG-------DDGMRGED---------GEI 600
Query: 1109 GSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRV--FTPRGV 1166
G + P P GT PGAP P A G P+G
Sbjct: 601 GPRGLPGEAGPRGLLGP---RGT----------PGAPGQPGMAGVDGPPGPKGNMGPQGE 647
Query: 1167 PSRRGRGGGRPPPQVCPG----WSPPAKSLAPKKPPTGPLP--------PSKEPLK-EKL 1213
P G+ G P PQ PG PP + KP LP P KE EK
Sbjct: 648 PGPPGQQGN-PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706
Query: 1214 IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEG 1273
GP P G G V DG R + G + +D P F+ + +G G
Sbjct: 707 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG-----DMGLKGDRG 760
Query: 1274 KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSE 1333
+ P GPE P+ A + D S QA E+ +
Sbjct: 761 EVGQIGPRGEDGPE----------GPKGRAGPTGDPGP--SGQAGEKGKLGVPGLPGYPG 808
Query: 1334 RRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGME 1393
R+G K + G PG G G++ G QR + S ++
Sbjct: 809 RQGPKGSTG-------FPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGAR----- 855
Query: 1394 RQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGP-GRGDKRSWPSPKNRSRPPEERPPGLPL 1452
GP GK G G+S G G GP G GP G +P PK PP + GLP
Sbjct: 856 ------GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK--DGLPG 907
Query: 1453 PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPS- 1511
P + QG PG PG PQGP+
Sbjct: 908 HPGQRGETGF------------------------QGKTGPPG------PGGVVGPQGPTG 937
Query: 1512 ----------PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRR 1561
P PP Q + + +PGP +G+ G AG+ FP +R
Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKD-GPAGLRGFPGER- 993
Query: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRK 1621
P + G G K G GPQ G+ R T+
Sbjct: 994 ---------------GLPGAQGAPGLK-GGEGPQGPPGPVGSPG------ERGSAGTAGP 1031
Query: 1622 SYRPSSMEPWMEPLSPFEDVA-GTEMSQSDSGVDLSGDSQVSSGPCSQRSSP--DG---- 1674
P P P E A G + Q +G D GP SP DG
Sbjct: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091
Query: 1675 ----GLKGA-----AEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE 1725
G KG+ GPP PG P+ A G G EP R E R
Sbjct: 1092 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG-EPGPRGQQGMFGQKGDEGARG 1150
Query: 1726 QPLPPGPIGTE--RSQRTDRGTEPGPIRPSHRPGPP 1759
P PPGPIG + ++G E G + P PGPP
Sbjct: 1151 FPGPPGPIGLQGLPGPPGEKG-ENGDVGPMGPPGPP 1185
Score = 94.4 bits (233), Expect = 1e-18
Identities = 301/1240 (24%), Positives = 375/1240 (30%), Gaps = 280/1240 (22%)
Query: 105 PPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSR 164
P + P P P PP P + P G A G G G L R
Sbjct: 405 PGPAGPAGIMGPPGLQGPTGPPGDPGDRG--PPGRPGLPGAD---GLPGPPGTMLMLPFR 459
Query: 165 FSRE--EFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDG--GGRGPDELEG 220
+ + + PT+ A Q +A ++ PGP T R G GG G +G
Sbjct: 460 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM-----GLTGRPGPVGGPGSSGAKG 514
Query: 221 PDSKLHHGHDPRGGLQPSGPPQFPPYRGM--------MPP---------FMYPPYLPFPP 263
+S PRG P GP P RG MP F P LP
Sbjct: 515 -ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
Query: 264 PY----GPQGPYRYPTPDG---------PSRFPRVAGPRGSGPPMRLVEPVGRPSILKED 310
+ GPQGP P DG P P AGPRG L+ P G P
Sbjct: 574 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPG----- 622
Query: 311 NLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP 370
G AG +G G + + GE P
Sbjct: 623 ---------APGQPGMAGV-----------------------DGPPGPKGNMGPQGEPGP 650
Query: 371 PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL-PPPHRGPAGNWGPPGDY 429
P G++GN P P+ G P P+ P+ PP +GP G G G
Sbjct: 651 P---GQQGN------PGPQ--------------GLPGPQGPIGPPGEKGPQGKPGLAG-L 686
Query: 430 PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEK 489
P GPP P E I R + + R K
Sbjct: 687 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV--------RGLKGSK 738
Query: 490 LKRLDEKFGA--PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETE-- 545
++ ++ F D LK + P PK P P S E
Sbjct: 739 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798
Query: 546 -----PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
P P + P ST PG G+ + P GP
Sbjct: 799 GVPGLPGYPGRQGPKGSTGFPGFP---------GANGEKGARGVAGKPGPRGQRGPTGPR 849
Query: 601 PPEEVPPPTTPPVPKVEPKGDG-IGPTRQPPSQG----LGYPKYQKSLPPRFQRQQQEQL 655
PT P PK GDG GP + QG +G+P + P ++ L
Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP----PGKDGL 905
Query: 656 LKQQQQHQWQQHQQGSAPPTP---VPPSPPQPVT--LGAVPAPQAPPPPPKALYPGALGR 710
Q Q + PP P V P P T +G P P PP + PGA G+
Sbjct: 906 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965
Query: 711 PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-----PGVH-------PSGLV--PR 756
DP I P L+G P P PG+ P G V P
Sbjct: 966 ----EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
Query: 757 ERSDSG-----GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
ER +G G P + P E+G P G P P
Sbjct: 1022 ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG 1081
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPL---------EEPGP- 861
++ DKG E P S ENG PGPP + P+ EPGP
Sbjct: 1082 SPGEDGDKGEIGE-------PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1134
Query: 862 --------------RPLPWPPGSDEVAKIQTPPPKK-EPPKEETAQLTGPEAGRKPARGV 906
R P PPG + + PP +K E GP R P
Sbjct: 1135 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1194
Query: 907 GSGG-QGPP---------PPRRESRTETRWGPRPGSSRRGIPPEEPG-----APPRRAGP 951
G+ G QGPP + E GP PG + G P E G PP AGP
Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGP 1253
Query: 952 IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
PP GD+ PK P P+ G G P E P G
Sbjct: 1254 PGAKGPP-------------GDDGPK-GNPGPVGF-PGDPGPPGEPGPAGQDGVGGDKGE 1298
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG--G 1069
D + GP G RG G G GR + + +G+ G G G
Sbjct: 1299 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR-------QGEKGAKGEAGAEGPPG 1351
Query: 1070 TGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKE 1129
GP P P G+ E IP ++G + ++ P
Sbjct: 1352 KTGPVGPQGPAGKPGPE------GLRGIPGPVGEQGLP----------GAAGQDGPPG-- 1393
Query: 1130 GTLTQVPLAPPP-PGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPP 1188
P+ PP PG P G + G P +G G R P SP
Sbjct: 1394 ------PMGPPGLPGLKGDPGSKGEKGHPGLIGL-IGPPGEQGEKGDRGLPGT--QGSPG 1444
Query: 1189 AKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG 1228
AK P GPL P P +PGP P GS G
Sbjct: 1445 AKGDGGIPGPAGPLGPPGPP----GLPGPQGPKGNKGSTG 1480
Score = 89.0 bits (219), Expect = 5e-17
Identities = 241/1007 (23%), Positives = 317/1007 (31%), Gaps = 220/1007 (21%)
Query: 211 GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL-------PFPP 263
G GP L GP + P G P G P G P +P P
Sbjct: 655 GNPGPQGLPGPQGPI----GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 710
Query: 264 PYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLK----EFDQLD 319
P GPQGP YP P G V G +GS G P + LK E Q+
Sbjct: 711 P-GPQGPIGYPGPRGVKGADGVRGLKGSKGEK---GEDGFPGFKGDMGLKGDRGEVGQIG 766
Query: 320 QENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP--------- 370
+DG G T D + E+G G G + P
Sbjct: 767 PRGEDGPEGPKGRAGPT-----GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 821
Query: 371 PEADGKKGNSPNSEPPTPKTAWAET-------SRPPETEPGPPAPK----PPLPPPHRGP 419
P A+G+KG + P P+ T +R P +PGP PP PP RGP
Sbjct: 822 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 881
Query: 420 AGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
G GP G +P GPP PP + QR +
Sbjct: 882 QGPQGPVG-FPGPKGPP-GPPGKDGLPGHPGQRGETG----------------------- 916
Query: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP---- 535
K G P P P T P + P PP PP
Sbjct: 917 -------------FQGKTGPPGPGGVVGPQGP-----TGETGPIGERGHPGPPGPPGEQG 958
Query: 536 -PASAPTPETEPEEPAQAPPAQSTPT-----------PGVAAAPTLVSGGGSTSSTSSGS 583
P +A + + Q + P PG AP L G G
Sbjct: 959 LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP-- 1016
Query: 584 FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG----IGPTRQPPSQG-LGYPK 638
SP E GP P P PP P E G GP + QG +G P
Sbjct: 1017 -VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP- 1074
Query: 639 YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP 698
+ P + ++ + + + +G P P PP PV + P
Sbjct: 1075 -GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-PGPPGLQGPVGAPGIAGGDGEPG 1132
Query: 699 P--PKALY-----PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPS 751
P + ++ GA G P P P+ + + PP P PPG P
Sbjct: 1133 PRGQQGMFGQKGDEGARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPG--PR 1188
Query: 752 GLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
G P+ + + G P + + E+G P G+ P + P
Sbjct: 1189 G--PQGPNGADGPQGPPGSVGSVGGVGEKGEP---------GEAGNPGPPGEAGVGGPKG 1237
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGS 870
+ ++ + G PP PP PG G PGP FP +PGP P P G
Sbjct: 1238 ERGEKGEAG-----PPGAAGPPGAKGPPGDDGPKGNPGP--VGFP-GDPGPPGEPGPAGQ 1289
Query: 871 DEVA--KIQTPPPKKEPPKEETAQL--TGPEAGRKPARGVGS-GGQGPPPPRRESRTETR 925
D V K + P + P + + GP R P G+ G QG + E+ E
Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE-- 1347
Query: 926 WGPRPGSSRRGIPPEEPGAPPRRAGP--IKKPPPPTKVEELPPKPLEQGDETPKPPKPDP 983
GP PG + P P P + GP ++ P P + LP + G P P P
Sbjct: 1348 -GP-PGKT----GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PPGPMGPPG 1399
Query: 984 LKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYG 1043
L KG G E G + +GP +G +G+ RG GT G
Sbjct: 1400 LPGLKGDPGSKGEKGHPGLIG------------LIGPPGEQGE-KGD-----RGLPGTQG 1441
Query: 1044 GRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQ 1103
G +GD G G GP PP P G + PK +
Sbjct: 1442 SPGA-------------KGDGGI-PGPAGPLGPPGPPGLPGPQG----------PKGNKG 1477
Query: 1104 RGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAP 1150
G + D P P P +P PPG P P
Sbjct: 1478 STGPAGQK--------GDSGLPGP--------PGSPGPPGEVIQPLP 1508
Score = 72.4 bits (176), Expect = 4e-12
Identities = 188/782 (24%), Positives = 237/782 (30%), Gaps = 105/782 (13%)
Query: 136 PSGVKSWAQASVTHGAHGDGGRASSL----LSRFSREEFPTLQAAGDQDKAAKERESAEQ 191
P G K A + G G G L L + + P A + A
Sbjct: 773 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832
Query: 192 SSG-PGPSLRPQNSTTWRDG--GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRG 248
+G PGP R Q T G G RGP GP GG P GPP +G
Sbjct: 833 VAGKPGP--RGQRGPTGPRGSRGARGPTGKPGPKGT-------SGGDGPPGPPGERGPQG 883
Query: 249 MMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILK 308
P +P P P G G +P G + F GP G G + P G +
Sbjct: 884 PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 943
Query: 309 EDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEE 368
E + G GA + E K G S ++G G R G
Sbjct: 944 ERG--HPGPPGPPGEQGLPGAAGK----EGAKGDPGPQG-ISGKDGPAGLRGFPGERGLP 996
Query: 369 RPPEADGKKGNSPNSEPPTPKTAWAET----SRPPETEPGPPAPK-PPLPPPHRGPAGNW 423
A G KG PP P + E + P PG P P+ PP P +G G
Sbjct: 997 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1056
Query: 424 GPPG-----------DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
GP G P GP P D+ E +K S + + E
Sbjct: 1057 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD----------KGE 1106
Query: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPP 532
+ A + D + G ++ A P PP P L P
Sbjct: 1107 NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG--PIGLQGLP 1164
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT-------LVSGGGSTSSTSSGSFE 585
PP + P P P + P A P V G G
Sbjct: 1165 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224
Query: 586 ASPVEPQL--PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKS 642
P E + P E E E PP P P GD GP P G G P
Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD-GPKGNPGPVGFPGDPG---- 1279
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV----PPSPP----QPVTLGAVPAPQ 694
PP + + + Q G PP P PP PP P GA
Sbjct: 1280 -PPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1336
Query: 695 APPPPPKALYPGALGRPPPMPPM----NFDPRWMM-IPPYVDPRLLQGRPPLDFYPPGVH 749
+A G G+ P+ P P + IP V + L G D P +
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396
Query: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809
P GL P + D G E+G P + + +G R L
Sbjct: 1397 PPGL-PGLKGDPGSKG-------------EKGHPGL---IGLIGPPGEQGEKGDRGLPGT 1439
Query: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPP 868
+ D G+ P+ PP P PG P G G S P + G LP PP
Sbjct: 1440 QGSPGAKGDGGIPGPAGPLGPPGP-----PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1494
Query: 869 GS 870
GS
Sbjct: 1495 GS 1496
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/301 (24%), Positives = 96/301 (31%), Gaps = 58/301 (19%)
Query: 57 PPPANLPSLKAENKGNDPNVSLV----PKDGTGWASKQEQSDPKSSDASTAQPPESQPLP 112
PP A P KGN V P G A + K D QP P
Sbjct: 1253 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312
Query: 113 ASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPT 172
+ P + PP A G + A GA G G+ +
Sbjct: 1313 EAGPPGPPGKRGPPGAAG-----AEGRQGEKGAKGEAGAEGPPGKTGPV----------- 1356
Query: 173 LQAAGDQDKAAKERESAEQSSGPGP-SLRPQNSTTWRDG--GGRGPDELEG----PDSKL 225
G Q A K + PGP + +DG G GP L G P SK
Sbjct: 1357 ----GPQGPAGKPGPEGLRGI-PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1411
Query: 226 HHGHDPRGGLQPSGPPQFPPYRGM--MPPFMYPPY------LPFPP-PYGPQGPYRYPTP 276
GH GL GPP +G +P P +P P P GP GP P P
Sbjct: 1412 EKGHPGLIGL--IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1469
Query: 277 DGPSRFPRVAGPRGS-------------GPPMRLVEPVGRPSILKEDNLKEFDQLDQEND 323
GP GP G GPP +++P+ P + + + + + + D
Sbjct: 1470 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL--PILSSKKTRRHTEGMQADAD 1527
Query: 324 D 324
D
Sbjct: 1528 D 1528
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 129 bits (325), Expect = 2e-29
Identities = 334/1326 (25%), Positives = 439/1326 (33%), Gaps = 274/1326 (20%)
Query: 536 PASAPTPETEPEEPAQAPPAQSTPT-------PGVAAAPTLVSGGGSTSSTSSGSFEASP 588
P S P E P PA+ +++ G P +V G + A
Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452
Query: 589 VEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP-KY--QKSLPP 645
+ P P +GP P P PP P DG+ PP L P +Y S P
Sbjct: 453 MGP--PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPG---PPGTMLMLPFRYGGDGSKGP 507
Query: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAV-----PAPQAPP--- 697
Q+ + QQ + G T P P + GA P PQ P
Sbjct: 508 TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 567
Query: 698 -PPPKALYPGALGRP--------PPMPPMNFDPRWMMIPPYVDPRLLQG-RPPLDFYPPG 747
PP PG GRP P P D + +P + +G R P PPG
Sbjct: 568 GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG--PPG 625
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTP--PVDPKLAWV-GDVFTATPAEPR 804
P R G P + +L RGTP P P +A V G P+
Sbjct: 626 P-PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684
Query: 805 PLTSPLRQAADEDDKGMRSETPPVPPP-------PPYLASYPGFP-------------EN 844
P Q + +G+ P+ PP P LA PG E
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
Query: 845 GAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPAR 904
GA GPP + P+ PGPR + G+D V ++ K E ++ G + G K R
Sbjct: 745 GALGPPGPQGPIGYPGPRGVK---GADGVRGLKGS--KGEKGEDGFPGFKG-DMGLKGDR 798
Query: 905 G-VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEE 963
G VG G PR E GP R G P +PG P +AG K P
Sbjct: 799 GEVGQIG-----PRGED------GPEGPKGRAG-PTGDPG-PSGQAGEKGKLGVPG---- 841
Query: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-------PAPRLRRDYSYE 1016
LP P QG KG G P NG P PR +R
Sbjct: 842 LPGYPGRQGP--------------KGSTGFPGFPGANGEKGARGVAGKPGPRGQR----- 882
Query: 1017 RVGPTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GP 1073
GPT RG RG G+ G +GT GG G E RG G G G GP
Sbjct: 883 --GPTGPRG-SRGARGPTGKPGPKGTSGGDGPPGPPGE-------RGPQGPQGPVGFPGP 932
Query: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSD---KEAPTPKEG 1130
PP P G+ + +P QRG ETG + P + PT + G
Sbjct: 933 KGPPGPPGK------------DGLPGHPGQRG-ETGFQGKTGPPGPGGVVGPQGPTGETG 979
Query: 1131 TLTQV--PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWS 1186
+ + P P PPG P A G P+G+ + G G G P + PG +
Sbjct: 980 PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP-GPQGISGKDGPAGLRGFPGERGLPG-A 1037
Query: 1187 PPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRRRH 1245
A L + P GP PGP+ SP RG + +G+
Sbjct: 1038 QGAPGLKGGEGPQGP-------------PGPVGSPGERGSAGTAGPIGLP---------- 1074
Query: 1246 GRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAK 1305
GR Q P E +G G+ + P PGP A
Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA--------------GPAG 1120
Query: 1306 SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPG 1364
SP + ++ E + +G+ P PP L P VG PG GG PG
Sbjct: 1121 SPG-------EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGDGEPG 1171
Query: 1365 ISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG 1424
+G Q+ D R F PG PGP G+ G +G G GP G G
Sbjct: 1172 PRGQ-QGMFGQKG-DEGARGFPGP-PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228
Query: 1425 PGRGDKRSWP-----SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQA 1479
P + P S + E+ PG P PP + V P G +
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV--------GGPKGERGE 1280
Query: 1480 LAQLSSRQGSVTAPGGH-------PRHKPG---LPQAPQGPSPRPPTRYEPQRVNSGLSS 1529
+ + G+ PG P+ PG P P P P + + G
Sbjct: 1281 KGE-AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1339
Query: 1530 DPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP---------RKPELLQEESLPPPH 1580
DP +PGP P AG P PP +R P K + + PP
Sbjct: 1340 DPG--QPGPP------GPSGEAG-PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1390
Query: 1581 SSGFLGSKPEGP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFE 1639
+G P GP GP + G + + + + + P M P L +
Sbjct: 1391 KTG-----PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP--PGLPGLK 1443
Query: 1640 DVAGTEMSQSDSGV----------DLSGDSQVSSGPCSQRSSPDGGLKGAA-----EGPP 1684
G++ + G+ GD + S + DGG+ G A GPP
Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503
Query: 1685 KRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPG----PIGTERSQR 1740
PG P GP G + P P P PPG P+ S++
Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPP----------GSPGPPGEVIQPLPILSSKK 1553
Query: 1741 TDRGTE 1746
T R TE
Sbjct: 1554 TRRHTE 1559
Score = 119 bits (298), Expect = 3e-26
Identities = 283/1165 (24%), Positives = 368/1165 (31%), Gaps = 285/1165 (24%)
Query: 678 PPSPPQPVTLGAVPA---PQAPP-------PPPKALYPGALGRPPPMPPMNFDPRWMMIP 727
PP P P + P P PP PP + PGA G P P M +M+P
Sbjct: 443 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM------LMLP 496
Query: 728 ----------PYVDPRLLQGRPPLDFY------PPGVHPSGLVPRERSDSGGSSSEPFDR 771
P + + Q + L PPG P GL R G SS
Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG--PMGLTGRPGPVGGPGSS----- 549
Query: 772 HAPAMLRERGTP-PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
E G P P P+ P P P ++ D G P
Sbjct: 550 ---GAKGESGDPGPQGPR---------GVQGPPGPTGKPGKRGRPGADGGRGM------P 591
Query: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEV-AKIQTPPPKKEPPKEE 889
P GF +G PG P + E GP+ P PPG D + + P+ P +
Sbjct: 592 GEPGAKGDRGF--DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 649
Query: 890 TAQLTGPEAGR-KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSR----RGIP-PEEPG 943
L GP P + +G GPP P+ + GP PG +G+P P+ P
Sbjct: 650 PRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP-PGQQGNPGPQGLPGPQGPI 708
Query: 944 APPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNL 1003
PP GP KP + LP D P P + KG LG P P G
Sbjct: 709 GPPGEKGPQGKPG----LAGLPG-----ADGPPGHPGKEGQSGEKGALGPPGPQGPIGY- 758
Query: 1004 SPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGD 1063
P PR + R G +G + F +G G G RG + RG+
Sbjct: 759 -PGPRGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP-------RGE 809
Query: 1064 DGRGG--GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS-----------ETGS 1110
DG G G GP P P G+ + + P R+ +GS E G+
Sbjct: 810 DGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA 869
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRR 1170
P + PT G+ A P G P P + G P G P R
Sbjct: 870 RGVAGKPGPRGQRGPTGPRGSRG----ARGPTG---KPGPKGTSGGDG----PPGPPGER 918
Query: 1171 GRGG-----GRPPPQVCPGWSPPAKSLAPKKPP-------------------TGPLPPSK 1206
G G G P P+ PG PP K P P GP P+
Sbjct: 919 GPQGPQGPVGFPGPKGPPG--PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 976
Query: 1207 E--PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQER 1264
E P+ E+ PGP P G G + G+ + G+ D P R ER
Sbjct: 977 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK----DGPAGLRGFPGER 1032
Query: 1265 -------ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA 1317
+G EG P +PG + T P R + P A
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP------GPA 1086
Query: 1318 NEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRA 1377
E+ + + R G VG PG G PG +G++ +
Sbjct: 1087 GEKGAPGEKGPQGPAGRDG----------VQGPVGLPGPAGPAGSPGEDG-DKGEIGEPG 1135
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSS-GGGGGGPGGRTGPGRGDKRSWPSP 1436
+ SK G + +N PGP G G G+ GG G PG R G ++
Sbjct: 1136 QKGSK--------GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187
Query: 1437 KNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH 1496
+ PP P GL P PP G V G
Sbjct: 1188 RGFPGPPG--PIGLQGLPGPPGEKG------------------------ENGDVGPMG-- 1219
Query: 1497 PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPF 1556
P PG P+ PQGP+ + P V S V GVG +P
Sbjct: 1220 PPGPPG-PRGPQGPNGADGPQGPPGSVGS--------------VGGVGEKGEPGEAGNPG 1264
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSK--PEGPGPQAESRDTGTEALTPHIWNRL 1614
PP K E ++ PP ++G G+K P GP+ G
Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF----------- 1313
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
P P EP GP Q G
Sbjct: 1314 ----------PGDPGPPGEP-----------------------------GPAGQDGV--G 1332
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
G KG +G P +PG P GPPG P P A +G + E G G
Sbjct: 1333 GDKGE-DGDPGQPGPPGPSGEAGPPGPPGKRGP--PGAAGAEGRQGE--------KGAKG 1381
Query: 1735 TERSQRTDRGTEP-GPIRPSHRPGP 1758
++ T P GP P+ +PGP
Sbjct: 1382 EAGAEGPPGKTGPVGPQGPAGKPGP 1406
Score = 111 bits (278), Expect = 7e-24
Identities = 339/1367 (24%), Positives = 434/1367 (31%), Gaps = 275/1367 (20%)
Query: 296 RLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD--EE 353
R V P+ ++E +E+ L E+ D E+ Y K E DGRDSD +
Sbjct: 323 RHVSGTNEPNPVEEIFTEEY--LTGEDYDSQRKNSEDTLYENK-----EIDGRDSDLLVD 375
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKT--------AWAETSR---PPETE 402
G G D E P + + P T T A+ E + P E
Sbjct: 376 GDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE 435
Query: 403 PGPPAPKPPLPPPHRGPAGNW---------GPPGDYPDRGGPPCKPPAPEDEDEAWRQRR 453
PG PP P GPAG GPPGD DR GPP +P P +
Sbjct: 436 PGMLVEGPPGPA---GPAGIMGPPGLQGPTGPPGDPGDR-GPPGRPGLPGADG-----LP 486
Query: 454 KQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPA 513
+ + L + QE + A ++ + P P
Sbjct: 487 GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQA-----------RIALRGPPGPMG 535
Query: 514 APSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEP--AQAPPAQSTPTPGVAAAPTLVS 571
P P P A + + P+ P Q PP T PG P
Sbjct: 536 LTGRPGP--------VGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADG 586
Query: 572 GGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG-IGPTRQPP 630
G G + P LP +G P PP DG IGP P
Sbjct: 587 GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646
Query: 631 SQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLG-- 688
G PR G P P +P QP G
Sbjct: 647 EAG-----------PR-----------------------GLLGPRGTPGAPGQPGMAGVD 672
Query: 689 AVPAPQA-------PPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
P P+ P PP + PG G P P P+ PP + QG+P L
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG--------PP--GEKGPQGKPGL 722
Query: 742 DFYPPGVHPSGLVPRE-RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
P P G +E +S G+ P + RG D G +
Sbjct: 723 AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKG-----SK 777
Query: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPG 860
E P D KG R E + P E+G GP P +PG
Sbjct: 778 GEKGEDGFP-GFKGDMGLKGDRGEVGQIGPR----------GEDGPEGPKGRAGPTGDPG 826
Query: 861 PRPLPWPPGSDEVAKIQTPP----PKKEPPKEETAQLTGPEA-GRKPARGVGS-----GG 910
P + E K+ P P ++ PK T P A G K ARGV G
Sbjct: 827 P-----SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881
Query: 911 QGPPPPR--RESRTET-RWGPRPGSSRRGIPPEEPG--APPRRAGPI-----KKPPPPTK 960
+GP PR R +R T + GP+ G+S PP PG P GP+ K PP P
Sbjct: 882 RGPTGPRGSRGARGPTGKPGPK-GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940
Query: 961 VEELPPKPLEQGDE----TPKPPKPDPLKITKGKLG-----------GPKETPPNGNLSP 1005
+ LP P ++G+ PP P + +G G GP P L
Sbjct: 941 KDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPG 1000
Query: 1006 A---PRLRRDYSYERV----GPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR 1058
A + D + + GP RG +G G GG G S
Sbjct: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
Query: 1059 EFRGDDGRGG-----GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETH 1113
E RG G G G GP PP P G +G+ E+ P+ R G
Sbjct: 1061 E-RGSAGTAGPIGLPGRPGPQGPPGPAG-------EKGAPGEKGPQGPAGRDGVQGPVGL 1112
Query: 1114 ESDLAPSDKEAPTPKEGTLTQV----------PLAPPPPGAPPSPAPARFTARGGRVFTP 1163
P+ +G + + PP P P A A G P
Sbjct: 1113 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP 1172
Query: 1164 RGVPSRRGRGG--------GRPPP---QVCPGWSPPAK-----SLAPKKPPTGPLPPSKE 1207
RG G+ G G P P Q PG PP + + P PP GP P +
Sbjct: 1173 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG--PPGEKGENGDVGPMGPP-GP-PGPRG 1228
Query: 1208 PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENA 1267
P GP P GS GG E GE G A P+ R ++ E
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG--PKGER-GEKGEAG 1285
Query: 1268 ARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASES 1327
G+ G P P GP+ V P P A ++ +
Sbjct: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---------AGQDGVGGDKG 1336
Query: 1328 SDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSS 1387
D GD P P + +A G PG G PG +A + G ++
Sbjct: 1337 ED------GDPGQPGPPGPSGEA-GPPGPPGKRGPPG-AAGAEGRQGEK----------- 1377
Query: 1388 QRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPSPKNRSRPPEER 1446
G + + GP GK G G G GP G G PG ++ P + PP
Sbjct: 1378 ---GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434
Query: 1447 -PPGLP-LPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--LSSRQGSVTAPGG------- 1495
PPGLP L P S + P G Q L QGS A G
Sbjct: 1435 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494
Query: 1496 ---HPRHKPGLPQAPQGP-SPRPPTRYEPQRVNSGLSSDPHFEEPGP 1538
P PGLP PQGP + T Q+ +SGL P PGP
Sbjct: 1495 GPLGPPGPPGLP-GPQGPKGNKGSTGPAGQKGDSGLPGPP--GSPGP 1538
Score = 106 bits (264), Expect = 3e-22
Identities = 242/936 (25%), Positives = 303/936 (32%), Gaps = 197/936 (21%)
Query: 882 KKEPPKEETAQLT-GPEAGRKPARGVGSGG-QGPPPPRRESRTETRWGPRPGSSRRGIPP 939
K EP E L GP PA +G G QGP P + G R R G+P
Sbjct: 428 KGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------GDRGPPGRPGLPG 481
Query: 940 EE--PGAP------PRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKIT--KG 989
+ PG P P R G P +E + + Q P P+ +T G
Sbjct: 482 ADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 541
Query: 990 KLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
+GGP + G P P+ R GPT G+ GRG G G +G
Sbjct: 542 PVGGPGSSGAKGESGDPGPQGPRGVQGPP-GPTGKPGKRGRPGADGGRGMPGEPGAKG-- 598
Query: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSET 1108
R F GD G G G P PP P G +G E+ E
Sbjct: 599 --DRGFDGLPGLPGDKGHRGERG-PQGPPGPPG-------DDGMRGED---------GEI 639
Query: 1109 GSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRV--FTPRGV 1166
G + P P GT PGAP P A G P+G
Sbjct: 640 GPRGLPGEAGPRGLLGP---RGT----------PGAPGQPGMAGVDGPPGPKGNMGPQGE 686
Query: 1167 PSRRGRGGGRPPPQVCPG----WSPPAKSLAPKKPPTGPLP--------PSKEPLK-EKL 1213
P G+ G P PQ PG PP + KP LP P KE EK
Sbjct: 687 PGPPGQQGN-PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
Query: 1214 IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEG 1273
GP P G G V DG R + G + +D P F+ + +G G
Sbjct: 746 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE-KGEDGFPGFKG-----DMGLKGDRG 799
Query: 1274 KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSE 1333
+ P GPE P+ A + D S QA E+ +
Sbjct: 800 EVGQIGPRGEDGPE----------GPKGRAGPTGDPGP--SGQAGEKGKLGVPGLPGYPG 847
Query: 1334 RRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGME 1393
R+G K + G PG G G++ G QR + S ++
Sbjct: 848 RQGPKGSTG-------FPGFPGANGEKGARGVAGKP-GPRGQRGPTGPRGSRGAR----- 894
Query: 1394 RQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGP-GRGDKRSWPSPKNRSRPPEERPPGLPL 1452
GP GK G G+S G G GP G GP G +P PK PP + GLP
Sbjct: 895 ------GPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK--DGLPG 946
Query: 1453 PPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPS- 1511
P + QG PG PG PQGP+
Sbjct: 947 HPGQRGETGF------------------------QGKTGPPG------PGGVVGPQGPTG 976
Query: 1512 ----------PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRR 1561
P PP Q + + +PGP +G+ G AG+ FP +R
Sbjct: 977 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP--QGISGKD-GPAGLRGFPGER- 1032
Query: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRK 1621
P + G G K G GPQ G+ R T+
Sbjct: 1033 ---------------GLPGAQGAPGLK-GGEGPQGPPGPVGSPG------ERGSAGTAGP 1070
Query: 1622 SYRPSSMEPWMEPLSPFEDVA-GTEMSQSDSGVDLSGDSQVSSGPCSQRSSP--DG---- 1674
P P P E A G + Q +G D GP SP DG
Sbjct: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130
Query: 1675 ----GLKGA-----AEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE 1725
G KG+ GPP PG P+ A G G EP R E R
Sbjct: 1131 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG-EPGPRGQQGMFGQKGDEGARG 1189
Query: 1726 QPLPPGPIGTE--RSQRTDRGTEPGPIRPSHRPGPP 1759
P PPGPIG + ++G E G + P PGPP
Sbjct: 1190 FPGPPGPIGLQGLPGPPGEKG-ENGDVGPMGPPGPP 1224
Score = 94.4 bits (233), Expect = 1e-18
Identities = 301/1240 (24%), Positives = 375/1240 (30%), Gaps = 280/1240 (22%)
Query: 105 PPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSR 164
P + P P P PP P + P G A G G G L R
Sbjct: 444 PGPAGPAGIMGPPGLQGPTGPPGDPGDRG--PPGRPGLPGAD---GLPGPPGTMLMLPFR 498
Query: 165 FSRE--EFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDG--GGRGPDELEG 220
+ + + PT+ A Q +A ++ PGP T R G GG G +G
Sbjct: 499 YGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM-----GLTGRPGPVGGPGSSGAKG 553
Query: 221 PDSKLHHGHDPRGGLQPSGPPQFPPYRGM--------MPP---------FMYPPYLPFPP 263
+S PRG P GP P RG MP F P LP
Sbjct: 554 -ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612
Query: 264 PY----GPQGPYRYPTPDG---------PSRFPRVAGPRGSGPPMRLVEPVGRPSILKED 310
+ GPQGP P DG P P AGPRG L+ P G P
Sbjct: 613 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPG----- 661
Query: 311 NLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP 370
G AG +G G + + GE P
Sbjct: 662 ---------APGQPGMAGV-----------------------DGPPGPKGNMGPQGEPGP 689
Query: 371 PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL-PPPHRGPAGNWGPPGDY 429
P G++GN P P+ G P P+ P+ PP +GP G G G
Sbjct: 690 P---GQQGN------PGPQ--------------GLPGPQGPIGPPGEKGPQGKPGLAG-L 725
Query: 430 PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEK 489
P GPP P E I R + + R K
Sbjct: 726 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV--------RGLKGSK 777
Query: 490 LKRLDEKFGA--PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETE-- 545
++ ++ F D LK + P PK P P S E
Sbjct: 778 GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837
Query: 546 -----PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
P P + P ST PG G+ + P GP
Sbjct: 838 GVPGLPGYPGRQGPKGSTGFPGFP---------GANGEKGARGVAGKPGPRGQRGPTGPR 888
Query: 601 PPEEVPPPTTPPVPKVEPKGDG-IGPTRQPPSQG----LGYPKYQKSLPPRFQRQQQEQL 655
PT P PK GDG GP + QG +G+P + P ++ L
Sbjct: 889 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP----PGKDGL 944
Query: 656 LKQQQQHQWQQHQQGSAPPTP---VPPSPPQPVT--LGAVPAPQAPPPPPKALYPGALGR 710
Q Q + PP P V P P T +G P P PP + PGA G+
Sbjct: 945 PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004
Query: 711 PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-----PGVH-------PSGLV--PR 756
DP I P L+G P P PG+ P G V P
Sbjct: 1005 ----EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
Query: 757 ERSDSG-----GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
ER +G G P + P E+G P G P P
Sbjct: 1061 ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG 1120
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPL---------EEPGP- 861
++ DKG E P S ENG PGPP + P+ EPGP
Sbjct: 1121 SPGEDGDKGEIGE-------PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR 1173
Query: 862 --------------RPLPWPPGSDEVAKIQTPPPKK-EPPKEETAQLTGPEAGRKPARGV 906
R P PPG + + PP +K E GP R P
Sbjct: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1233
Query: 907 GSGG-QGPP---------PPRRESRTETRWGPRPGSSRRGIPPEEPG-----APPRRAGP 951
G+ G QGPP + E GP PG + G P E G PP AGP
Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP-PGEAGVGGPKGERGEKGEAGPPGAAGP 1292
Query: 952 IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
PP GD+ PK P P+ G G P E P G
Sbjct: 1293 PGAKGPP-------------GDDGPK-GNPGPVGF-PGDPGPPGEPGPAGQDGVGGDKGE 1337
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG--G 1069
D + GP G RG G G GR + + +G+ G G G
Sbjct: 1338 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR-------QGEKGAKGEAGAEGPPG 1390
Query: 1070 TGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKE 1129
GP P P G+ E IP ++G + ++ P
Sbjct: 1391 KTGPVGPQGPAGKPGPE------GLRGIPGPVGEQGLP----------GAAGQDGPPG-- 1432
Query: 1130 GTLTQVPLAPPP-PGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPP 1188
P+ PP PG P G + G P +G G R P SP
Sbjct: 1433 ------PMGPPGLPGLKGDPGSKGEKGHPGLIGL-IGPPGEQGEKGDRGLPGT--QGSPG 1483
Query: 1189 AKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG 1228
AK P GPL P P +PGP P GS G
Sbjct: 1484 AKGDGGIPGPAGPLGPPGPP----GLPGPQGPKGNKGSTG 1519
Score = 89.0 bits (219), Expect = 5e-17
Identities = 241/1007 (23%), Positives = 317/1007 (31%), Gaps = 220/1007 (21%)
Query: 211 GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL-------PFPP 263
G GP L GP + P G P G P G P +P P
Sbjct: 694 GNPGPQGLPGPQGPI----GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 749
Query: 264 PYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLK----EFDQLD 319
P GPQGP YP P G V G +GS G P + LK E Q+
Sbjct: 750 P-GPQGPIGYPGPRGVKGADGVRGLKGSKGEK---GEDGFPGFKGDMGLKGDRGEVGQIG 805
Query: 320 QENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP--------- 370
+DG G T D + E+G G G + P
Sbjct: 806 PRGEDGPEGPKGRAGPT-----GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 860
Query: 371 PEADGKKGNSPNSEPPTPKTAWAET-------SRPPETEPGPPAPK----PPLPPPHRGP 419
P A+G+KG + P P+ T +R P +PGP PP PP RGP
Sbjct: 861 PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGP 920
Query: 420 AGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
G GP G +P GPP PP + QR +
Sbjct: 921 QGPQGPVG-FPGPKGPP-GPPGKDGLPGHPGQRGETG----------------------- 955
Query: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP---- 535
K G P P P T P + P PP PP
Sbjct: 956 -------------FQGKTGPPGPGGVVGPQGP-----TGETGPIGERGHPGPPGPPGEQG 997
Query: 536 -PASAPTPETEPEEPAQAPPAQSTPT-----------PGVAAAPTLVSGGGSTSSTSSGS 583
P +A + + Q + P PG AP L G G
Sbjct: 998 LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP-- 1055
Query: 584 FEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG----IGPTRQPPSQG-LGYPK 638
SP E GP P P PP P E G GP + QG +G P
Sbjct: 1056 -VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP- 1113
Query: 639 YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP 698
+ P + ++ + + + +G P P PP PV + P
Sbjct: 1114 -GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP-PGPPGLQGPVGAPGIAGGDGEPG 1171
Query: 699 P--PKALY-----PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPS 751
P + ++ GA G P P P+ + + PP P PPG P
Sbjct: 1172 PRGQQGMFGQKGDEGARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPG--PR 1227
Query: 752 GLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
G P+ + + G P + + E+G P G+ P + P
Sbjct: 1228 G--PQGPNGADGPQGPPGSVGSVGGVGEKGEP---------GEAGNPGPPGEAGVGGPKG 1276
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGS 870
+ ++ + G PP PP PG G PGP FP +PGP P P G
Sbjct: 1277 ERGEKGEAG-----PPGAAGPPGAKGPPGDDGPKGNPGP--VGFP-GDPGPPGEPGPAGQ 1328
Query: 871 DEVA--KIQTPPPKKEPPKEETAQL--TGPEAGRKPARGVGS-GGQGPPPPRRESRTETR 925
D V K + P + P + + GP R P G+ G QG + E+ E
Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE-- 1386
Query: 926 WGPRPGSSRRGIPPEEPGAPPRRAGP--IKKPPPPTKVEELPPKPLEQGDETPKPPKPDP 983
GP PG + P P P + GP ++ P P + LP + G P P P
Sbjct: 1387 -GP-PGKT----GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG--PPGPMGPPG 1438
Query: 984 LKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYG 1043
L KG G E G + +GP +G +G+ RG GT G
Sbjct: 1439 LPGLKGDPGSKGEKGHPGLIG------------LIGPPGEQGE-KGD-----RGLPGTQG 1480
Query: 1044 GRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQ 1103
G +GD G G GP PP P G + PK +
Sbjct: 1481 SPGA-------------KGDGGI-PGPAGPLGPPGPPGLPGPQG----------PKGNKG 1516
Query: 1104 RGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAP 1150
G + D P P P +P PPG P P
Sbjct: 1517 STGPAGQK--------GDSGLPGP--------PGSPGPPGEVIQPLP 1547
Score = 72.4 bits (176), Expect = 4e-12
Identities = 188/782 (24%), Positives = 237/782 (30%), Gaps = 105/782 (13%)
Query: 136 PSGVKSWAQASVTHGAHGDGGRASSL----LSRFSREEFPTLQAAGDQDKAAKERESAEQ 191
P G K A + G G G L L + + P A + A
Sbjct: 812 PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871
Query: 192 SSG-PGPSLRPQNSTTWRDG--GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRG 248
+G PGP R Q T G G RGP GP GG P GPP +G
Sbjct: 872 VAGKPGP--RGQRGPTGPRGSRGARGPTGKPGPKGT-------SGGDGPPGPPGERGPQG 922
Query: 249 MMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILK 308
P +P P P G G +P G + F GP G G + P G +
Sbjct: 923 PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 982
Query: 309 EDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEE 368
E + G GA + E K G S ++G G R G
Sbjct: 983 ERG--HPGPPGPPGEQGLPGAAGK----EGAKGDPGPQG-ISGKDGPAGLRGFPGERGLP 1035
Query: 369 RPPEADGKKGNSPNSEPPTPKTAWAET----SRPPETEPGPPAPK-PPLPPPHRGPAGNW 423
A G KG PP P + E + P PG P P+ PP P +G G
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1095
Query: 424 GPPG-----------DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
GP G P GP P D+ E +K S + + E
Sbjct: 1096 GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD----------KGE 1145
Query: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPP 532
+ A + D + G ++ A P PP P L P
Sbjct: 1146 NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG--PIGLQGLP 1203
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT-------LVSGGGSTSSTSSGSFE 585
PP + P P P + P A P V G G
Sbjct: 1204 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263
Query: 586 ASPVEPQL--PSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKS 642
P E + P E E E PP P P GD GP P G G P
Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD-GPKGNPGPVGFPGDPG---- 1318
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV----PPSPP----QPVTLGAVPAPQ 694
PP + + + Q G PP P PP PP P GA
Sbjct: 1319 -PPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1375
Query: 695 APPPPPKALYPGALGRPPPMPPM----NFDPRWMM-IPPYVDPRLLQGRPPLDFYPPGVH 749
+A G G+ P+ P P + IP V + L G D P +
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435
Query: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809
P GL P + D G E+G P + + +G R L
Sbjct: 1436 PPGL-PGLKGDPGSKG-------------EKGHPGL---IGLIGPPGEQGEKGDRGLPGT 1478
Query: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGPRPLPWPP 868
+ D G+ P+ PP P PG P G G S P + G LP PP
Sbjct: 1479 QGSPGAKGDGGIPGPAGPLGPPGP-----PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533
Query: 869 GS 870
GS
Sbjct: 1534 GS 1535
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/301 (24%), Positives = 96/301 (31%), Gaps = 58/301 (19%)
Query: 57 PPPANLPSLKAENKGNDPNVSLV----PKDGTGWASKQEQSDPKSSDASTAQPPESQPLP 112
PP A P KGN V P G A + K D QP P
Sbjct: 1292 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351
Query: 113 ASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPT 172
+ P + PP A G + A GA G G+ +
Sbjct: 1352 EAGPPGPPGKRGPPGAAG-----AEGRQGEKGAKGEAGAEGPPGKTGPV----------- 1395
Query: 173 LQAAGDQDKAAKERESAEQSSGPGP-SLRPQNSTTWRDG--GGRGPDELEG----PDSKL 225
G Q A K + PGP + +DG G GP L G P SK
Sbjct: 1396 ----GPQGPAGKPGPEGLRGI-PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1450
Query: 226 HHGHDPRGGLQPSGPPQFPPYRGM--MPPFMYPPY------LPFPP-PYGPQGPYRYPTP 276
GH GL GPP +G +P P +P P P GP GP P P
Sbjct: 1451 EKGHPGLIGL--IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP 1508
Query: 277 DGPSRFPRVAGPRGS-------------GPPMRLVEPVGRPSILKEDNLKEFDQLDQEND 323
GP GP G GPP +++P+ P + + + + + + D
Sbjct: 1509 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL--PILSSKKTRRHTEGMQADAD 1566
Query: 324 D 324
D
Sbjct: 1567 D 1567
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 129 bits (324), Expect = 3e-29
Identities = 325/1347 (24%), Positives = 412/1347 (30%), Gaps = 308/1347 (22%)
Query: 264 PYGPQGPYRYPTPDGPSRF---PRVAGPRGS-GPPMRLVEPVGRPSILKEDNLKEFDQLD 319
P G +GP P P GP P V G G+ GPP G PS D L
Sbjct: 142 PRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPP-------GHPSHPGPDGLSRPFSAQ 194
Query: 320 QENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGN 379
D +G +V G G G R Q G++ G
Sbjct: 195 MAGLDEKSGLGSQV-------------GLMPGSVGPVGPRGPQGLQGQQ-----GGAGPT 236
Query: 380 SPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGP---- 435
P EP P SR PE PG P G G G PG+ G P
Sbjct: 237 GPPGEPGDPGPMGPIGSRGPEGPPGKPGED--------GEPGRNGNPGEVGFAGSPGARG 288
Query: 436 -PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEE--------ERRMQEERRAAC 486
P P P + + + E+ + R M ER
Sbjct: 289 FPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG 348
Query: 487 AEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPP----PAVPKELPAPPAP-------- 534
+ G P K P P + P P A P P P
Sbjct: 349 PQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408
Query: 535 PPASAPTPETEPEEPAQAPPAQSTPT--PGVAAAPTLVSGGGSTS---STSSGSFEASPV 589
PP +P P PT PG + P GS ST P
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG 468
Query: 590 EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGI-GPTRQPPSQGLGYPKYQKSLPPRFQ 648
+P +P +G P+ P P P P +G GP P + G P ++ P
Sbjct: 469 DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528
Query: 649 RQQQEQLLKQQQQHQWQQHQQGSAPPTPV---PPSPPQPVTLGA--------VPAPQAPP 697
+ L + Q ++ GS+ P P P +P GA V P+
Sbjct: 529 FPGSDGL-PGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKL 587
Query: 698 PPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRE 757
P A PG GRP P + ++G+P P P G
Sbjct: 588 GPLGA--PGEDGRPGPPGSIG----------------IRGQPGSMGLPG---PKG----- 621
Query: 758 RSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADED 817
S G +P + + +RG P D G+V + P P L +
Sbjct: 622 ---SSGDPGKPGEAGNAGVPGQRGAPGKD------GEVGPSGPVGPPGLAGERGEQGPPG 672
Query: 818 DKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWP---------P 868
G + P PP PP PG + G PG P + PL G R P P
Sbjct: 673 PTGFQGL--PGPPGPPGEGGKPG--DQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLP 728
Query: 869 GSDEVAKIQTPP-PKKEPPKEETAQLTGPEA--GRKPARGVGSGGQGPPPPRRESRTETR 925
G +A P PK P T TGP G RG+ +G GP R +
Sbjct: 729 GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGI-AGTPGPKGDRGGIGEKGA 787
Query: 926 WGPRPGSSRRGIPPEEPGAPPRRAGPI-KKPPPPTKVEELPP----KPLEQGDETPK--- 977
G RG+P P PP AGP +K P + PP P +G+ P
Sbjct: 788 EGTAGNDGARGLPG--PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAV 845
Query: 978 ----PPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFA 1033
P PD KG+ G P + G SP P+ G G
Sbjct: 846 GFAGPQGPDGQPGVKGEPGEPGQKGDAG--SPGPQ-------GLAGSPGPHGPNGVPGLK 896
Query: 1034 RGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSE 1093
GRG +G G G F G GR G G P P P G G
Sbjct: 897 GGRGTQGPPGATG-------------FPGSAGRVGPPG-PAGAPGPAGPL-------GEP 935
Query: 1094 YEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARF 1153
+E P R + GS D P+ +G P PG P PA
Sbjct: 936 GKEGPPGLR---GDPGSHGRVGDRGPAGPPGGPGDKGD----PGEDGQPGPDGPPGPAGT 988
Query: 1154 TARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLPP--SKEPL 1209
T + G V G+P +RG G G P P PG P + K PP GP+ P S P+
Sbjct: 989 TGQRGIV----GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP-GPVGPPGSNGPV 1043
Query: 1210 KEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAAR 1269
E PGP P G+ G GER R G A
Sbjct: 1044 GE---PGPEGPAGNDGTPGRDGAV---GERGDRGDPGPA------------------GLP 1079
Query: 1270 GSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSD 1329
GS+G P P APG
Sbjct: 1080 GSQGAPGTPGPVGAPGD------------------------------------------- 1096
Query: 1330 FTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQR 1389
+ +RGD + P+ G PG G +PG RGD D R R
Sbjct: 1097 --AGQRGDPGSRGPI-------GPPGRAGKRGLPGPQG-PRGDKGDHG-DRGDRGQKGHR 1145
Query: 1390 --PGMERQNRRPGPGGKAGSSG---------------SSSGGGGGGPGGRTGPGRGDKRS 1432
G++ PGP G+ GS+G S G GP G GP G + S
Sbjct: 1146 GFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGP-PGVRGS 1204
Query: 1433 WPSPKNRSRPPEERPPGLPLPP----------------PPPSSSAVFRLDQVI----HSN 1472
P E PPG P PP P F DQ +
Sbjct: 1205 VGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKT 1264
Query: 1473 PAGIQQALAQLSSRQGSVTAPGGHPRH 1499
G+ L LSS+ ++ +P G +H
Sbjct: 1265 DPGVHATLKSLSSQIETMRSPDGSKKH 1291
Score = 119 bits (299), Expect = 2e-26
Identities = 339/1395 (24%), Positives = 420/1395 (30%), Gaps = 315/1395 (22%)
Query: 497 FGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPE-EPAQAPPA 555
FG K K EP P + P P PP + P E P+ P P
Sbjct: 107 FGRGRKGQKGEPGLVPVVTGI--------RGRPGPAGPPGSQGPRGERGPKGRPGPRGPQ 158
Query: 556 QSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPK 615
PGV P +P P PS GP+ P +
Sbjct: 159 GIDGEPGVPGQP------------------GAPGPPGHPSHPGPDGLSR--PFSAQMAGL 198
Query: 616 VEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT 675
E G G P S G P+ + L Q QQG A PT
Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGL----------------------QGQQGGAGPT 236
Query: 676 PVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLL 735
P P P +G + + PP K PG G P N +P + R
Sbjct: 237 GPPGEPGDPGPMGPIGSRGPEGPPGK---PGEDGE----PGRNGNPGEVGFAGSPGARGF 289
Query: 736 QGRPPLDFYPPGVH----------PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPV 785
G P L PG+ P G V S + P P L RG P
Sbjct: 290 PGAPGL----PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP--LGPRGMPGE 343
Query: 786 DPKLAWVGDV----FTATPAEPRPL--------------------TSPLRQAADEDDKGM 821
+L G P +P P+ P E +G
Sbjct: 344 RGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQ 403
Query: 822 RSETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEP---GPRPLPWPPGSDEVAKIQ 877
R ET P P PG P G G P ++ P P GP PPGS
Sbjct: 404 RGETGPPGP-----VGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458
Query: 878 TPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPR--PGSSRR 935
P + P + EAG K G G QGP P E E + GPR PG+
Sbjct: 459 GPQGIRGQPGDPGVPGFKGEAGPKGEPG-PHGIQGPIGPPGE---EGKRGPRGDPGTVGP 514
Query: 936 GIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDP-------LKITK 988
P E GAP R P P K + P+ G PK + DP L +
Sbjct: 515 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPV--GSSGPKGSQGDPGRPGEPGLPGAR 572
Query: 989 GKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGR-GFRGTYGGRGR 1047
G G P P G L P D R GP G RG+ G G G +G
Sbjct: 573 GLTGNPGVQGPEGKLGPLGAPGED---GRPGPP-------GSIGIRGQPGSMGLPGPKGS 622
Query: 1048 GARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSE 1107
GD G+ G G P RG + S P +RG +
Sbjct: 623 S-------------GDPGKPGEAGNAG-VPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ 668
Query: 1108 TGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVP 1167
PT +G +P P PPG P G V P G
Sbjct: 669 -------------GPPGPTGFQG----LPGPPGPPGEGGKPGDQGVPGDPGAV-GPLGPR 710
Query: 1168 SRRGRGGGRPPPQV--CPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGG 1225
RG G R P + PG A P P P P PG P G
Sbjct: 711 GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG--------TPGDTGPPGLQG 762
Query: 1226 SNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPG 1285
G + G P+ R G + ++ G++G L P PG
Sbjct: 763 MPGERGIAGTPG--PKGDRGG-------------IGEKGAEGTAGNDGARGLPGPLGPPG 807
Query: 1286 PEEALTTVTVAPAPRRAAAKSPDLSNQNSDQAN-------------EEWETASESSDFTS 1332
P T P PR N S N + + +
Sbjct: 808 P-AGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEP 866
Query: 1333 ERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGM 1392
++GD +P P L G+PG G VPG+ G +Q + S+ R G
Sbjct: 867 GQKGDAGSPGPQGL----AGSPGPHGPNGVPGLKG---GRGTQGPPGATGFPGSAGRVGP 919
Query: 1393 ERQNRRPGPGGKAGSSGSSSGGG-GGGPG--GRTGPGRGDKRSWPSPKNRSRPPEERPPG 1449
PGP G G G G G PG GR G RG P ++ P E+ PG
Sbjct: 920 PGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVG-DRGPAGPPGGPGDKGDPGEDGQPG 978
Query: 1450 LPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH-PRHKPGLPQAPQ 1508
PP P A + ++G V PG R PGLP
Sbjct: 979 PDGPPGP------------------------AGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014
Query: 1509 GPSPRPPT-----RYEPQRVNSGLSSDPHFEEPGPM-VRGVGGTPRDSAGVSPFPPKRRE 1562
P PT + P V S+ P EPGP G GTP V +R +
Sbjct: 1015 TPGKVGPTGATGDKGPPGPVGPPGSNGP-VGEPGPEGPAGNDGTPGRDGAVG----ERGD 1069
Query: 1563 RPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKS 1622
R P L P S G P PGP D G
Sbjct: 1070 RGDPGPAGL-------PGSQG----APGTPGPVGAPGDAGQRG----------------- 1101
Query: 1623 YRPSSMEPWMEP-LSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKG--- 1678
P S P P + + G + + D G D G KG
Sbjct: 1102 -DPGSRGPIGPPGRAGKRGLPGPQGPRGDKG--------------DHGDRGDRGQKGHRG 1146
Query: 1679 --AAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTE 1736
+G P PG + + GP G R PP P KE P P GPIG
Sbjct: 1147 FTGLQGLPGPPGPNGEQGSAGIPGPFGP----RGPPGPVGPSGKE---GNPGPLGPIGPP 1199
Query: 1737 RSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVS 1796
R G E GP P PGPP G L +GD + E S+ + +P
Sbjct: 1200 -GVRGSVG-EAGPEGPPGEPGPP---GPPGPPGHLTAALGDIMGHYDE---SMPDPLPEF 1251
Query: 1797 RDWELLPSAAASAEP 1811
+ + P +P
Sbjct: 1252 TEDQAAPDDKNKTDP 1266
Score = 100 bits (250), Expect = 1e-20
Identities = 244/1028 (23%), Positives = 318/1028 (30%), Gaps = 227/1028 (22%)
Query: 195 PGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMM---- 250
PG S P N + G G EGP + RG P GP P G +
Sbjct: 374 PGSSGFPGNPGMKGEAGPTGARGPEGPQGQ-------RGETGPPGPVGSPGLPGAIGTDG 426
Query: 251 ----------------PPFMYPPYLPFPP-PYGPQGPYRYPTPDGPSRFPRVAGPRGSGP 293
P PP P P GPQG P G F AGP+G
Sbjct: 427 TPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG 486
Query: 294 PMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEE 353
P + P+G P E + D G G V E
Sbjct: 487 PHGIQGPIGPPG--------EEGKRGPRGDPGTVGPPGPV-----------------GER 521
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP 413
GA G+R + G P A G++G +S PK + + RP EPG P +
Sbjct: 522 GAPGNRGFPGSDGLPGPKGAQGERGPVGSS---GPKGSQGDPGRP--GEPGLPGARGLTG 576
Query: 414 PPH-RGPAGNWGP---PGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARR 469
P +GP G GP PG+ R GPP K SS + E
Sbjct: 577 NPGVQGPEGKLGPLGAPGE-DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGN- 634
Query: 470 RREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPA-------PPP 522
+ + GAP K + P+ P P P P
Sbjct: 635 ---------------------AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGP 673
Query: 523 AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSG-GGSTSSTSS 581
+ LP PP PP P Q P A P G G+
Sbjct: 674 TGFQGLPGPPGPPGEGG------------KPGDQGVPGDPGAVGPLGPRGERGNPGERGE 721
Query: 582 GSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQK 641
P E + GP+ P+ P P+ P G T P QG+ +
Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTP-----------GDTGPPGLQGMPGERGIA 770
Query: 642 SLP-PRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV-PPSPPQPVTLGAVPAPQAPPPP 699
P P+ R + ++ + P P+ PP P P P P+ P
Sbjct: 771 GTPGPKGDRGG----IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826
Query: 700 PKAL-YPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRER 758
P + PG+ G P + F P+ G+ PGV P ++
Sbjct: 827 PGSRGNPGSRGENGPTGAVGF----------AGPQGPDGQ-------PGVKGEPGEPGQK 869
Query: 759 SDSG--------GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPL 810
D+G GS P + RGT + G P P P
Sbjct: 870 GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA 929
Query: 811 RQAADEDDKGMRSETPPVPPPPPYLASYPG----FPENGAPGPPISRFPLEEPGPRPLPW 866
+ +G PP L PG + G GPP +PG P
Sbjct: 930 GPLGEPGKEG-----------PPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG 978
Query: 867 PPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG-VGSGGQ----GPPPPRRESR 921
P G PP GP AG RG VG GQ G P +
Sbjct: 979 PDG---------PP--------------GP-AGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014
Query: 922 TETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPP--PTKVEELPPKP---LEQGDETP 976
T + GP + +G P P PP GP+ +P P P + P + E+GD
Sbjct: 1015 TPGKVGPTGATGDKG--PPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGD 1072
Query: 977 KPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARG- 1035
P P G G P P G A + S +GP G+ RG +G
Sbjct: 1073 PGPAGLP-----GSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGK-RGLPGPQGP 1126
Query: 1036 RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYE 1095
RG +G +G RG R + +R F G G G PP P G +GS
Sbjct: 1127 RGDKGDHGDRG----DRGQKGHRGFTGLQGLPG-------PPGPNG-------EQGSAGI 1168
Query: 1096 EIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV-PLAPPPPGAPPSP--APAR 1152
P R G E + P P G++ + P PP PP P P
Sbjct: 1169 PGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGH 1228
Query: 1153 FTARGGRV 1160
TA G +
Sbjct: 1229 LTAALGDI 1236
Score = 99.8 bits (247), Expect = 3e-20
Identities = 307/1250 (24%), Positives = 392/1250 (31%), Gaps = 269/1250 (21%)
Query: 103 AQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAH-GDGGRASSL 161
A PP SQ + P R P + P VP + A H +H G G
Sbjct: 134 AGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPG--QPGAPGPPGHPSHPGPDG----- 186
Query: 162 LSR-FSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEG 220
LSR FS Q AG +K+ + GP G RGP L+G
Sbjct: 187 LSRPFSA------QMAGLDEKSGLGSQVGLMPGSVGPV------------GPRGPQGLQG 228
Query: 221 PDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDG-P 279
+GG P+GPP P G M P GP+GP P DG P
Sbjct: 229 Q----------QGGAGPTGPPGEPGDPGPMGPI---------GSRGPEGPPGKPGEDGEP 269
Query: 280 SR--FPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTE 337
R P G GS G P + K + + + G G+ E T
Sbjct: 270 GRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLE--GPKGEVGAPGSKGEAGPTG 327
Query: 338 KL--------KFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPK 389
+ + E GR +GA G R + G+ P G G+S P K
Sbjct: 328 PMGAMGPLGPRGMPGERGR-LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMK 386
Query: 390 TAWAET-SRPPE------TEPGPPAP--KPPLP--------PPHRGPAGNWGPPGDYPDR 432
T +R PE E GPP P P LP P +GP G+ G G P
Sbjct: 387 GEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGP-PGS 445
Query: 433 GGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKR 492
GPP P P+ R +
Sbjct: 446 AGPP-GSPGPQGSTGPQGIRGQPGDP---------------------------------- 470
Query: 493 LDEKFGAPDKRLKAEPAAPPAAPSTPAP--PPAVPKELPAPPAPPPASAPTPETEPEEPA 550
G P + +A P P P PP + P P P E P
Sbjct: 471 -----GVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525
Query: 551 QAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTT 610
S PG A GS+ S P EP LP G V P
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585
Query: 611 PPVPKVEPKGDG-------IGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
P P DG IG QP S GL PK P + + + Q+
Sbjct: 586 KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK-PGEAGNAGVPGQRGAP 644
Query: 664 WQQHQQGSAPPTPVP--------PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMP 715
+ + G + P P PP P +P P P PP + PG G P
Sbjct: 645 GKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGP--PGPPGEGGKPGDQGVPG--- 699
Query: 716 PMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSE-PFDRHAP 774
DP + P + PR +G P + PG+ +GL P E+ +GG + P P
Sbjct: 700 ----DPG--AVGP-LGPRGERGNPG-ERGEPGI--TGL-PGEKGMAGGHGPDGPKGSPGP 748
Query: 775 A-MLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPP 833
+ + G P + G T P R + G R P+ PP
Sbjct: 749 SGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPP-- 806
Query: 834 YLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQL 893
G GP + EPGPR L PPGS + P
Sbjct: 807 -----------GPAGPTGEK---GEPGPRGLVGPPGS-----------RGNP-------- 833
Query: 894 TGPEAGRKPARGVG-SGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGP- 951
G P VG +G QGP +PG P EPG P
Sbjct: 834 -GSRGENGPTGAVGFAGPQGP-------------DGQPGVKGE---PGEPGQKGDAGSPG 876
Query: 952 ---IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008
+ P P +P L+ G T PP + G++G P P G PA
Sbjct: 877 PQGLAGSPGPHGPNGVP--GLKGGRGTQGPPGATGFPGSAGRVGPP---GPAGAPGPAGP 931
Query: 1009 LRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG 1068
L + GP RG RG G GG G +GD G
Sbjct: 932 LGEP---GKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD-------------KGDPGE-D 974
Query: 1069 GTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSE--TGSETHESDLAPS----DK 1122
G GP+ PP P G T +P +R +RG G + P+ DK
Sbjct: 975 GQPGPDGPPGPAGTTGQR------GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028
Query: 1123 EAPTPKEGTLTQVPLAPPPPGAPP--SPAPARFTARGGRVFT----PRGVPSRRGRGGGR 1176
P P + P+ P P P P R A G R P G+P +G G
Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG-APGT 1087
Query: 1177 PPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMED 1236
P P PG + + GP+ P K L PGP P G +G +
Sbjct: 1088 PGPVGAPGDAGQRGDPGSR----GPIGPPGRAGKRGL-PGPQGPRGDKGDHG------DR 1136
Query: 1237 GERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286
G+R ++ G Q P N +GS G P P PGP
Sbjct: 1137 GDRGQKGHRGFTGLQGLP------GPPGPNGEQGSAGIPGPFGPRGPPGP 1180
Score = 81.6 bits (200), Expect = 7e-15
Identities = 212/870 (24%), Positives = 279/870 (32%), Gaps = 176/870 (20%)
Query: 1109 GSETHESDLAPSDKEAPTPKEGT-----LTQVPLAPPPPGAPPSPAPARFTARGGRVFTP 1163
GS+ + P + P +G + P AP PPG P P P + R F+
Sbjct: 138 GSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS----RPFSA 193
Query: 1164 R--GVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLS 1219
+ G+ + G G G P V P + L ++ GP P EP PGP+
Sbjct: 194 QMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGD----PGPMG 249
Query: 1220 PVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKP--------PRFRRLKQER------- 1264
P+ G G EDGE R G P P LK R
Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEG 309
Query: 1265 ---ENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
E A GS+G+ T P A GP PR + L Q +
Sbjct: 310 PKGEVGAPGSKGEAGPTGPMGAMGPL----------GPRGMPGERGRLGPQGAPGQRG-- 357
Query: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGG--GGAVPGISAMSRGDLSQRAKD 1379
+ K P L P + G PG G G A P + G QR +
Sbjct: 358 ----------AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407
Query: 1380 LSKRSFSSQR-PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGP----------GRG 1428
S PG + PG G GS G+S G GP G GP G+
Sbjct: 408 GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467
Query: 1429 DKRSWPSPKNRSRPP-EERPPGL--PLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ--- 1482
P K + P E P G+ P+ PP R D P + + A
Sbjct: 468 GDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNR 527
Query: 1483 -LSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNS-GLSSDPHFEEP---- 1536
G G P P+G P EP + GL+ +P + P
Sbjct: 528 GFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKL 587
Query: 1537 GPM-VRGVGGTP--------RDSAGVSPFP-PKRRERPPRKPELLQEESLP----PPHSS 1582
GP+ G G P R G P PK P KP +P P
Sbjct: 588 GPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD 647
Query: 1583 GFLGSKPEGP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDV 1641
G +G P GP GP + + G + P+ + P P
Sbjct: 648 GEVG--PSGPVGPPGLAGERGEQG----------------PPGPTGFQGLPGPPGP---- 685
Query: 1642 AGTEMSQSDSGVDLSGDSQVSSGPCSQRSSP----DGGLKGAAEGPPKRPGGSSPLNAVP 1697
G D GV + GP +R +P + G+ G G GG P
Sbjct: 686 PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG-LPGEKGMAGGHGP----- 739
Query: 1698 CEGPPGSEPPRRPPPAPHDGDRKELPREQPL--PPGPIGTERSQRTDRGTE--------- 1746
+GP GS P P + +P E+ + PGP G +R ++G E
Sbjct: 740 -DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKG-DRGGIGEKGAEGTAGNDGAR 797
Query: 1747 --PGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPS 1804
PGP+ P PGP G + LV + P SR
Sbjct: 798 GLPGPLGP---PGPAGPTGEKGEPGPRGLVGPPGSRGN-----------PGSRGENGPTG 843
Query: 1805 AAASAEPQSKNLDSGHCVPEPSSSGQR-----LYPEVFYGSAGP-SSSQISG--GAMDSQ 1856
A A PQ + G EP GQ+ P+ GS GP + + G G +Q
Sbjct: 844 AVGFAGPQGPDGQPG-VKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902
Query: 1857 LHPNSGGFRPGTPSLHPYRSQPLYLPPGPA 1886
P + GF PG S PPGPA
Sbjct: 903 GPPGATGF-PG--------SAGRVGPPGPA 923
Score = 71.2 bits (173), Expect = 1e-11
Identities = 150/585 (25%), Positives = 195/585 (33%), Gaps = 94/585 (16%)
Query: 1342 PPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGP 1401
PP P TPGGG + RG Q+ + P + RPGP
Sbjct: 88 PPGECCPVCSQTPGGGN-------TNFGRGRKGQKGEP-------GLVPVVTGIRGRPGP 133
Query: 1402 GGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSA 1461
G GS G G GP GR GP RG + P +P PPG P P P S
Sbjct: 134 AGPPGSQGPR---GERGPKGRPGP-RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSR 189
Query: 1462 VFRLDQVIHSNPAGIQQALAQLSSRQGSV----------TAPGGHPRHKPGLP------- 1504
F +G+ + + G V G P PG P
Sbjct: 190 PFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMG 249
Query: 1505 ----QAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTP--RDSAGVSPFPP 1558
+ P+GP +P EP R + PG + G G+P R G P
Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGN----------PGEV--GFAGSPGARGFPGAPGLPG 297
Query: 1559 KRRERPPRKPELLQEESLPPPHSSGFLGSKPE-GP-GPQAESRDTGTEALTPHIWNRLHT 1616
+ R + E P G GSK E GP GP G + P RL
Sbjct: 298 LKGHRGHKGLE-------GPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGM-PGERGRLGP 349
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSG---DSQVSSGPCSQR--SS 1671
+ M P+ P + G+ + G+ ++ GP QR +
Sbjct: 350 QGAPGQRGAHGMPGKPGPMGPL-GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408
Query: 1672 PDG-----GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSE-PPRRPPPAPHDGDRKELPRE 1725
P G GL GA G PG P + GPPGS PP P P G + R
Sbjct: 409 PPGPVGSPGLPGAI-GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG--IRG 465
Query: 1726 QPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKEL 1785
QP PG G + + +G EPGP GPP + G D V E+
Sbjct: 466 QPGDPGVPGF-KGEAGPKG-EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGA 523
Query: 1786 TAS----VTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSA 1841
+ ++ +P + + S+ P+ D G EP G R G
Sbjct: 524 PGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR-PGEPGLPGAR-------GLT 575
Query: 1842 GPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLP-PGP 1885
G Q G + P G RPG P R QP + PGP
Sbjct: 576 GNPGVQGPEGKLGPLGAPGEDG-RPGPPGSIGIRGQPGSMGLPGP 619
Score = 60.8 bits (146), Expect = 1e-08
Identities = 204/923 (22%), Positives = 261/923 (28%), Gaps = 230/923 (24%)
Query: 80 PKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGV 139
PK G S PK S +P E LP ++ N + P PL
Sbjct: 538 PKGAQGERGPVGSSGPKGSQGDPGRPGEPG-LPGARGLTGNPGVQGPEGKLG-PL----- 590
Query: 140 KSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSL 199
GA G+ GR S R + ++ G + + + E + P
Sbjct: 591 ----------GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640
Query: 200 RPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL 259
R G G D GP P GPP RG P +
Sbjct: 641 R----------GAPGKDGEVGPSG-------------PVGPPGLAGERGEQGPPGPTGFQ 677
Query: 260 PFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLD 319
P P GP G P G P GP G G P I
Sbjct: 678 GLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGI-----------TG 726
Query: 320 QENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGN 379
+ G AG H +G +G G+ PP G G
Sbjct: 727 LPGEKGMAGGH--------------------GPDGPKGSPGPSGTPGDTGPPGLQGMPGE 766
Query: 380 SPNSEPPTPK-------TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDR 432
+ P PK AE + + G P PL PP GPAG G G+ R
Sbjct: 767 RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG---PLGPP--GPAGPTGEKGEPGPR 821
Query: 433 G--GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKL 490
G GPP P E + + AV A + + + ++ E
Sbjct: 822 GLVGPPGSRGNPGSRGE----------NGPTGAVGFAGPQGPDGQPGVKGEP-------- 863
Query: 491 KRLDEKFGAPDKRLKAEPAAPPAAPSTPAP--PPAVP-----KELPAPPAPPPASAPTPE 543
G P ++ A P +P P P VP + PP
Sbjct: 864 -------GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGR 916
Query: 544 TEPEEPAQAP-PAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP 602
P PA AP PA PG P L GS A P P P +G
Sbjct: 917 VGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRG-PAGP--PGGPGDKGDPGE 973
Query: 603 EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQH 662
+ P P PP P G T Q G+ + ++ +P
Sbjct: 974 DGQPGPDGPPGP--------AGTTGQRGIVGMPGQRGERGMP------------------ 1007
Query: 663 QWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPR 722
P P P P P PP + G +G P P P D
Sbjct: 1008 --------GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGS--NGPVGEPGPEGPAGND-- 1055
Query: 723 WMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGT 782
G P D G+ E DR P G+
Sbjct: 1056 --------------GTPGRD--------------------GAVGERGDRGDPGPAGLPGS 1081
Query: 783 PPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP 842
P P P+ +P A D G R P PP A
Sbjct: 1082 --------------QGAPGTPGPVGAP-GDAGQRGDPGSRG-----PIGPPGRAG----- 1116
Query: 843 ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEE-TAQLTGPEAGRK 901
+ G PGP R + G R G +Q P P E+ +A + GP R
Sbjct: 1117 KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRG 1176
Query: 902 PARGVG-SGGQGPPPPRRESRTETRWGP-RPGSSRRGIPPEEPGAPPRRAGPIKKPPPPT 959
P VG SG +G P P GP P R + P PP GP P PP
Sbjct: 1177 PPGPVGPSGKEGNPGP---------LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227
Query: 960 KVEELPPKPLEQGDETPKPPKPD 982
+ + DE+ P P+
Sbjct: 1228 HLTAALGDIMGHYDESMPDPLPE 1250
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 124 bits (311), Expect = 1e-27
Identities = 142/510 (27%), Positives = 193/510 (37%), Gaps = 106/510 (20%)
Query: 511 PPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAP-PAQSTPTPGVAAAPTL 569
PP +P P + P+PP PPP P P P P P P+QS P+ G +AAP
Sbjct: 607 PPLSPQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG-SAAPMF 664
Query: 570 VSGGGST----SSTSSGSFEASPVEPQLPSKE-GPE---PPEEVPPPTTPPVPKVEPKGD 621
V T +S SG+ P P + S+ P+ PP V PP PP P P G
Sbjct: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTP-GS 723
Query: 622 GIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVP-PS 680
+ + P P++ PP L Q QH Q PP P+P P
Sbjct: 724 AMAQLKPAPC-APSLPQFSAPPPP---------LKIHQVQHITQVAPPTPPPPPPIPAPL 773
Query: 681 PPQ--PVTLGAVPAP-----------QAPPPPPKALYPGALGRPPPMPPMNFDPRW--MM 725
PPQ P L +PAP QA PP P PP+PP P +
Sbjct: 774 PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP----------TPPVPPAKKQPAFPASY 823
Query: 726 IPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGT--P 783
IPP PP PP P +P+++S P P+++++ + P
Sbjct: 824 IPP---------SPPT---PPVPVPPPTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQFP 870
Query: 784 PVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPE 843
P A PA P + P +A + + + PVP P FP
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK----WQPSSIPVPS--------PDFP- 917
Query: 844 NGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPA 903
P PP S P P P+P PP PPP P +++ G+K +
Sbjct: 918 ---PPPPESSLVFPPPPPSPVPAPP--------PPPPPTASPTPDKSG-----SPGKKTS 961
Query: 904 RGVGSGGQGPPP-PRRESRTETRWGPRPGSSRRG---------IPPEEPGAPPRRA-GPI 952
+ GG+ PPP P+R S ++ G +R PP E G+P + P
Sbjct: 962 KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP 1021
Query: 953 KKPPPPTKVEELP---PKPLEQGDETPKPP 979
PP P K+ P L+QG + K P
Sbjct: 1022 AAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051
Score = 100 bits (250), Expect = 1e-20
Identities = 163/658 (24%), Positives = 219/658 (33%), Gaps = 183/658 (27%)
Query: 394 ETSRPPETEPGPP-APKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQR 452
E+ P T PP +P+P + P+ A PP P PP PP P Q
Sbjct: 596 ESMNRPYTSLVPPLSPQPKIVTPY--TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS 653
Query: 453 RKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPP 512
+ S + V + + +L+ + GA K P PP
Sbjct: 654 APSAGSAAPMFV------------------KYSTITRLQNASQHSGALFK-----PPTPP 690
Query: 513 AAPSTPAPPP-AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVS 571
S P VP PP PPP PP PTPG A A
Sbjct: 691 VMQSQSVKPQILVPPNGVVPPPPPP----------------PP---PPTPGSAMA----- 726
Query: 572 GGGSTSSTSSGSFEASPVEPQLPSKEGPEPP---------EEVPPPTTPPVPKVEPKGDG 622
+ +P P LP P PP +V PPT PP P +
Sbjct: 727 -----------QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI------ 769
Query: 623 IGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPP 682
P PP PK ++P + ++ Q +APPTP PP PP
Sbjct: 770 --PAPLPPQ---APPKPLVTIPAPTSTKTVAPVVTQ------------AAPPTPTPPVPP 812
Query: 683 ---QPVTLGAVPA---PQAPPPPPKALYPGAL-------GRPPPMPPMNFDPRWMMIPPY 729
QP A PA P +PP PP + P L +PPP P P +P
Sbjct: 813 AKKQP----AFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP---LSP----VPSV 861
Query: 730 VDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKL 789
V Q PP PP + L P PA + + P V K
Sbjct: 862 VKQIASQFPPPPT--PPAMESQPLKP-----------------VPANVAPQSPPAVKAKP 902
Query: 790 AWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGP 849
W ++ P P +++ S P PPPPP AS P ++G+PG
Sbjct: 903 KWQP---SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS-PTPDKSGSPGK 958
Query: 850 PISRFPL---EEPGP---------------RPLPWPPGSDEVAKIQTPPPKKEPPKEETA 891
S+ ++P P P P P D + TPP + P +ET
Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKET- 1017
Query: 892 QLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGI-----PPEEPGAPP 946
L P A KP + + G P ++ + G + + PP + PP
Sbjct: 1018 -LPPPAAPPKPGK-LNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075
Query: 947 RRAGPIKKPPPPTKVEELPPKPLE-----QGDETPKPPKPDPLKITKGKLGGPKETPP 999
PPP T ELP P+E G+ +PK +P K+ K PP
Sbjct: 1076 --------PPPET---ELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122
Score = 100 bits (248), Expect = 2e-20
Identities = 198/799 (24%), Positives = 262/799 (32%), Gaps = 197/799 (24%)
Query: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQK-SLPP 645
+P PS P PP PPP PP P P P++ PS G P + K S
Sbjct: 617 TPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPL-----PSQSAPSAGSAAPMFVKYSTIT 671
Query: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYP 705
R Q Q + Q P VPP+ G VP P PPPPP P
Sbjct: 672 RLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN-------GVVPPPPPPPPPPT---P 721
Query: 706 G-ALGRPPPMPPMNFDPRWMMIPPYVD----PRLLQGRPPLDFYPPGVHPSGLVPRERSD 760
G A+ + P P P++ PP + + Q PP PP + P+ L P+
Sbjct: 722 GSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI-PAPLPPQAPPK 780
Query: 761 SGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKG 820
+ P A + + PP T TP P P A+
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPP------------TPTPPVPPAKKQPAFPASYIPPS- 827
Query: 821 MRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPL-PWPPGSDEVAKIQTP 879
TPPVP PPP L F +P P PL P P ++A P
Sbjct: 828 --PPTPPVPVPPPTLPKQQSF--------------CAKPPPSPLSPVPSVVKQIASQFPP 871
Query: 880 PPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPP 939
PP PP E+ L A P Q PP + + +W P IP
Sbjct: 872 PPT--PPAMESQPLKPVPANVAP--------QSPPAVK----AKPKWQPS------SIPV 911
Query: 940 EEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKP-PKPDPLKITKGKLGGPKETP 998
P PP PPP PP P P P P P P P
Sbjct: 912 PSPDFPP---------PPPESSLVFPPPP-------PSPVPAPPP--------------P 941
Query: 999 PNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR 1058
P SP P D S G G+
Sbjct: 942 PPPTASPTP----DKS----------------------------GSPGKKT--------- 960
Query: 1059 EFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLA 1118
+ GG PP P+ R +S S G+E+ E PKR ++ S
Sbjct: 961 ------SKTSSPGGKKPPPTPQ-RNSSIKSSSGAEHPE-PKR-------PSVDSLVSKFT 1005
Query: 1119 PSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRG-GGRP 1177
P E+ +P + TL PPP APP P + +G S + GR
Sbjct: 1006 PP-AESGSPSKETL-------PPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRG 1057
Query: 1178 PPQVCPGWSPPAKSLAPKKPPTG--PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGME 1235
V SPP+ S P PP PLPP + P + G SP V +
Sbjct: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP---AVFSGNTSP----------KVAVV 1104
Query: 1236 DGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAP-GPEEALTTVT 1294
+ +P++ ++ P R +R R A SE T+ P P+ +L+
Sbjct: 1105 N-PQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163
Query: 1295 --VAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVG 1352
+A R KS S + + TA+ D PPP LL+ +
Sbjct: 1164 GFLADLNRTLQRKSITRHGSLSSRMSRAEPTAT-MDDMA------LPPPPPELLSDQ--- 1213
Query: 1353 TPGGGGGGAVPGISAMSRG 1371
G GG + G + + RG
Sbjct: 1214 QKAGYGGSHISGYATLRRG 1232
Score = 85.9 bits (211), Expect = 4e-16
Identities = 178/783 (22%), Positives = 244/783 (31%), Gaps = 209/783 (26%)
Query: 158 ASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQN--STTWRDGGGRGP 215
+SS+ S S P Q + + +S + P +R Q+ S+ + + RG
Sbjct: 531 SSSIKSGSSSSSIPE-----SQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGT 585
Query: 216 DELEGPDSKLHHGHDPRGGLQPSGPPQ---FPPYRGMMPPFMYPPYLPFPPPYGPQGPYR 272
E +++ + P L P PQ PY P PP P PPP P P
Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPS---PPLPPPPPPPPPPPP-- 640
Query: 273 YPTPDGPSRFPRVAGPR-GSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHE 331
P P P P + P GS PM +K + Q + +
Sbjct: 641 -PPPPPPPPLPSQSAPSAGSAAPM----------FVKYSTITRLQNASQHSGALFKPPTP 689
Query: 332 EVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTA 391
V ++ +K + +G PP P PPTP +A
Sbjct: 690 PVMQSQSVK-----------------PQILVPPNGVVPPPP--------PPPPPPTPGSA 724
Query: 392 WAETSRPPETEPGPP---APKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEA 448
A+ +P P P AP PPL PP P PP P P
Sbjct: 725 MAQL-KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP---PPIPAPLPP----- 775
Query: 449 WRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP 508
Q+ + + + AP P
Sbjct: 776 ------QAPPKPLVTIP---------------------------------APTSTKTVAP 796
Query: 509 AAPPAAPSTPAPPPAVPKELPAPPA----PPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
AAP TP PP K+ PA PA P P + P P P P Q P ++
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Query: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG 624
P++V + F P P + S+ P V P +PP K +PK
Sbjct: 857 PVPSVV-------KQIASQFPPPPTPPAMESQPLKPVPANV-APQSPPAVKAKPKWQ--- 905
Query: 625 PTRQP-PSQGLGYPKYQKSL--PPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVP-PS 680
P+ P PS P + SL PP PP+PVP P
Sbjct: 906 PSSIPVPSPDFPPPPPESSLVFPP--------------------------PPPSPVPAPP 939
Query: 681 PPQPVTLGAVPAPQAPP--PPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGR 738
PP P T P P K PG +PPP P N + + +P+ R
Sbjct: 940 PPPPPTASPTPDKSGSPGKKTSKTSSPGG-KKPPPTPQRNSSIKSSSGAEHPEPK----R 994
Query: 739 PPLD-----FYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
P +D F PP ++SG S E L PP KL G
Sbjct: 995 PSVDSLVSKFTPP------------AESGSPSKE--------TLPPPAAPPKPGKLNLSG 1034
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPP----VPPPPPYLASYPGFPENGAPGP 849
+ + D + +PP PPPP PE P P
Sbjct: 1035 VNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP---------PETELPLP 1085
Query: 850 PISRFPLEEPG----------PRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAG 899
PI P G P+P W S ++ PP P + ++ +LT E
Sbjct: 1086 PI-EIPAVFSGNTSPKVAVVNPQPQQWSKMS-----VKKAPPPTRPKRNDSTRLTQAEIS 1139
Query: 900 RKP 902
+P
Sbjct: 1140 EQP 1142
Score = 61.2 bits (147), Expect = 1e-08
Identities = 121/508 (23%), Positives = 165/508 (32%), Gaps = 77/508 (15%)
Query: 1085 SETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGA 1144
SE G++ EE K R + + + L+P K TP + PL PPPP
Sbjct: 578 SEAWKRGTQLEESSKARMESMNRPYTSL-VPPLSPQPKIV-TPYTASQPSPPLPPPPPPP 635
Query: 1145 PPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQ------VCPGWSPPAKSLAPKKPP 1198
PP P P P +PS+ G P + + S A KPP
Sbjct: 636 PPPPPPP--------PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 1199 TGPLPPSKEPLKEKLIPG----PLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKP 1254
T P+ S+ + L+P P P GS + +P Q P
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ---LKPAPCAPSLPQFSAPP 744
Query: 1255 P--RFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQ 1312
P + +++ + A P + P P + L T+ PAP +P ++
Sbjct: 745 PPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI---PAPTSTKTVAPVVTQA 801
Query: 1313 NSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGD 1372
A + F + PPV + P + P A P S +S
Sbjct: 802 APPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL--PKQQSFCAKPPPSPLS--P 857
Query: 1373 LSQRAKDL-SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKR 1431
+ K + S+ P ME Q +P P A S P K
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS---------------PPAVKAKP 902
Query: 1432 SWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVT 1491
W +P P PPPPP SS VF P+ +
Sbjct: 903 KW-------QPSSIPVPSPDFPPPPPESSLVFP-----PPPPSPVPAPPPPPPPTASPTP 950
Query: 1492 APGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSA 1551
G P K +P G P PPT PQR NS + S E P P P +
Sbjct: 951 DKSGSPGKKTSKTSSPGGKKP-PPT---PQR-NSSIKSSSGAEHPEPK------RPSVDS 999
Query: 1552 GVSPFPPKRRERPPRKPELLQEESLPPP 1579
VS F P P K E+LPPP
Sbjct: 1000 LVSKFTPPAESGSPSK------ETLPPP 1021
Score = 56.2 bits (134), Expect = 3e-07
Identities = 91/383 (23%), Positives = 124/383 (32%), Gaps = 103/383 (26%)
Query: 380 SPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKP 439
SP+ PP P+++ PP P PP P PP P +G+ G G P
Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972
Query: 440 PAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGA 499
P P+ + SS + S E +R + + + A + G+
Sbjct: 973 PTPQ----------RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPA----------ESGS 1012
Query: 500 PDKRLKAEPAAPP-----------------------AAPSTPAPPPAVPKELPAPPAPPP 536
P K PAAPP AP E P+PP+
Sbjct: 1013 PSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD 1072
Query: 537 ASAPTPETE-PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPS 595
P PETE P P + P S G+TS + + V PQ P
Sbjct: 1073 FPPPPPETELPLPPIEIPAVFS----------------GNTSP------KVAVVNPQ-PQ 1109
Query: 596 KEGPEPPEEVPPPTTPP------VPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQR 649
+ ++ PPPT P + + E T P Q PK S+ P F
Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP--QVPTSPKSSLSVQPGFLA 1167
Query: 650 QQQEQLLKQQ-QQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPP-------K 701
L ++ +H + A PT + PPPPP K
Sbjct: 1168 DLNRTLQRKSITRHGSLSSRMSRAEPT------------ATMDDMALPPPPPELLSDQQK 1215
Query: 702 ALYPGA-------LGR-PPPMPP 716
A Y G+ L R PPP PP
Sbjct: 1216 AGYGGSHISGYATLRRGPPPAPP 1238
Score = 53.1 bits (126), Expect = 3e-06
Identities = 127/519 (24%), Positives = 170/519 (32%), Gaps = 101/519 (19%)
Query: 1432 SWPSPKNRSRPPEERPPGLPLPPPPP-----------SSSAVFRLDQVIHSNPAGIQQAL 1480
S PSP PP PP P PPPPP S++ +F V +S +Q A
Sbjct: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF----VKYSTITRLQNA- 676
Query: 1481 AQLSSRQGSVTAPGGHP-----RHKPGLPQAPQGPSPRPPTRYEPQRVNSGLS------- 1528
S G++ P P KP + P G P PP P S ++
Sbjct: 677 ---SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPC 733
Query: 1529 --SDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLG 1586
S P F P P ++ + + P PP PP P L ++ P P L
Sbjct: 734 APSLPQFSAPPPPLK-IHQVQHITQVAPPTPPP----PPPIPAPLPPQAPPKP-----LV 783
Query: 1587 SKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEM 1646
+ P P T+A P + A + ++ P+S P P P T
Sbjct: 784 TIP-APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF-PASYIPPSPPTPPVPVPPPTLP 841
Query: 1647 SQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPG-GSSPLNAVPCEGPPGSE 1705
Q S ++ P S S + PP P S PL VP P S
Sbjct: 842 KQQ------SFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP 895
Query: 1706 P-----------------PRRPPPAPHDG--DRKELPREQPLPPGPIGTERSQRTDRGTE 1746
P P PPP P P P PP P S D+
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGS 955
Query: 1747 PG-PIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEK--ELTASVTEAIPV----SRDW 1799
PG + PG T ++S ++ G K + + V++ P S
Sbjct: 956 PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 1800 ELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLH- 1858
E LP AA +P NL SG L + G + +SG DS +
Sbjct: 1016 ETLPPPAAPPKPGKLNL-----------SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEF 1064
Query: 1859 ---PNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSG 1894
P+ F P P L LPP P A+ SG
Sbjct: 1065 PSPPSDSDFPPPPPETE------LPLPPIEIP--AVFSG 1095
Score = 53.1 bits (126), Expect = 3e-06
Identities = 112/472 (23%), Positives = 154/472 (32%), Gaps = 93/472 (19%)
Query: 1690 SSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGP 1749
S P +P PP PP PPP P + P P + R ++
Sbjct: 622 SQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG 681
Query: 1750 --IRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAA 1807
+P P PPV S K L +P + ++P
Sbjct: 682 ALFKP---PTPPVMQSQSVKPQIL---------------------VPPNG---VVPPPPP 714
Query: 1808 SAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPG 1867
P + P P + P + SA P +I +Q+ P + P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 1868 TPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLY----- 1922
P+ P ++ P L PAP S + T K PA Y
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSP 828
Query: 1923 -------PPPSFLYSPAFC----PSPL-PDTSLL-QVRQDLP---SPSDFYSTPLQPGGQ 1966
PPP+ +FC PSPL P S++ Q+ P +P S PL+P
Sbjct: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV-P 887
Query: 1967 SGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPP-PAPPPLSLLPVGPALQPPSLAVRP 2025
+ P PA + S +PV P+P P PPP S L P P A P
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPV-------PSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 2026 PPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSG 2085
PP P A P P G K +S PG + PPT +
Sbjct: 941 PPPPT-------ASPTPDKSGSP-------------GKKTSKTSSPGGKKPPPTPQR--- 977
Query: 2086 LNSRLKATPSTYSGVFRTQRVD-LYQQASPPDALRWIPKPWERTGPPPREGP 2136
NS +K++ + VD L + +PP P + T PPP P
Sbjct: 978 -NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE---SGSPSKETLPPPAAPP 1025
Score = 52.8 bits (125), Expect = 4e-06
Identities = 109/424 (25%), Positives = 139/424 (32%), Gaps = 71/424 (16%)
Query: 1678 GAAEGPPKRPGGSS----PLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPR-------EQ 1726
GA PP P S P VP G PP PPP P + P +
Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF 740
Query: 1727 PLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELT 1786
PP P+ + Q + P P P PP+ + LV + + K +
Sbjct: 741 SAPPPPLKIHQVQHITQVAPPTP-----PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA 795
Query: 1787 ASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSS 1846
VT+A P + + P+ A P S S P P + F A P S
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF--CAKPPPS 853
Query: 1847 QISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLY-LPPGPAPPSALLSGLALKGQFLDFS 1905
+S + S + + F P P+ SQPL +P AP S K Q
Sbjct: 854 PLS--PVPSVVKQIASQFPP-PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 1906 TMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGG 1965
P +++PPP SP P P P + SP S PGG
Sbjct: 911 VPSPDFPPPPPESSLVFPPPP--PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG 968
Query: 1966 Q----------SGFLPSGAPAQQMLLPMVDSQL----PVVNFGSL------PPAPPPAPP 2005
+ S SGA + P VDS + P GS PPA PP P
Sbjct: 969 KKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG 1028
Query: 2006 PLSLLPV--------------GPAL------------QPPSLAVRPPPAPATRVLPSPAR 2039
L+L V P L PPS + PPP P T LP P
Sbjct: 1029 KLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETE-LPLPPI 1087
Query: 2040 PFPA 2043
PA
Sbjct: 1088 EIPA 1091
Score = 47.0 bits (110), Expect = 2e-04
Identities = 98/425 (23%), Positives = 152/425 (35%), Gaps = 57/425 (13%)
Query: 1780 KAEKELTASVTEAIPVSR---DWELLPSAA------ASAEPQSKN-----LDSGHCVPEP 1825
K K+L + EA+ + DW L S++ +S+ P+S++ DSG +P
Sbjct: 504 KYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQP 563
Query: 1826 SSS--GQRLYPEVFYGS--AGPSSSQISGGAMDSQLHPNSGGFRPGTPS---LHPYR--- 1875
+ Q + VF + G + S M+S P + P +P + PY
Sbjct: 564 AGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQ 623
Query: 1876 -SQPLYLPPGPAPP---------------SALLSGLALKGQFLDFSTMQATELGKLPAGG 1919
S PL PP P PP SA +G A F+ +ST+ + +G
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP-MFVKYSTITRLQNASQHSGA 682
Query: 1920 VLYPP-PSFLYSPAFCPSPL-PDTSLLQVRQDLPSPSDFYST--PLQPGGQSGFLPS-GA 1974
+ PP P + S + P L P ++ P P S L+P + LP A
Sbjct: 683 LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA 742
Query: 1975 PAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVL 2034
P + + V V PP PPP PP P+ P P L P P V
Sbjct: 743 PPPPLKIHQVQHITQVA-----PPTPPPPPP--IPAPLPPQAPPKPLVTIPAPTSTKTVA 795
Query: 2035 PSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATP 2094
P + P + + P + +P + + P PPT ++ +P
Sbjct: 796 PVVTQAAPPT-PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP 854
Query: 2095 STYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAE---EPGSRGDKEP 2151
+ Q + P A+ P P+ P+ +A+ +P S P
Sbjct: 855 LSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP 914
Query: 2152 GLPPP 2156
PPP
Sbjct: 915 DFPPP 919
Score = 35.4 bits (80), Expect = 0.61
Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 9/174 (5%)
Query: 35 KPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASK---QE 91
KP +P + S+ K IA + PPP P+++++ P ++ P+ +K Q
Sbjct: 849 KPPPSPLSPVPSVVK-QIASQFPPPPTPPAMESQPLKPVP-ANVAPQSPPAVKAKPKWQP 906
Query: 92 QSDPKSSDASTAQPPESQ----PLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASV 147
S P S PPES P P S PA P P A+P G K+ +S
Sbjct: 907 SSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP 966
Query: 148 THGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRP 201
+ +S + S E P + +K AE S +L P
Sbjct: 967 GGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPP 1020
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 123 bits (308), Expect = 2e-27
Identities = 200/795 (25%), Positives = 272/795 (34%), Gaps = 150/795 (18%)
Query: 362 QSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPP--PHRGP 419
++ +R + G + ++ P TP A A SR TE G P P P P P GP
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 420 AGNWGPPGDY------------PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERA 467
+ ++ P GG +P + A S + RA
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 468 RRRREEEERR-MQEER-------RAACAEKLKRLDEK-FGAPDKR-LKAEPAAPPAAPST 517
+ + + +Q R R A L L P KA P PP +T
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 518 PAP---PPAVPKELPAPPAPP-PASAPTPETEPEEPA----QAPPAQSTP---------- 559
P P PP+ P P P APP P++ P+ +T P PA QAPP+ +TP
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 560 -----------TPGVAAAPTLVSGGGSTSSTSSGS---------FEASPVEPQL----PS 595
+P + A P+ ++ ++TS GS SP + Q PS
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445
Query: 596 KEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQ--KSLPPRFQRQQQE 653
+ PP+ P +P P + P P S L Q SL +
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 654 QLLKQQQQHQWQQHQQGSAPP---TP-----VPP-------SPPQ------PVTLGAVPA 692
L+ + Q APP TP PP +PP P+T +
Sbjct: 506 SLIMPPLETQ-----SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
Query: 693 PQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRP-----PLDFYPPG 747
P P P P P L PPP P + PP + LQG P PL PP
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPA-----------MLRERGTPPVDPKLAWVGDVF 796
P +P ++ +S P A +L+ +PP P +
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ------ 674
Query: 797 TATPAEPRPLTSPLRQAADEDDKGMRSETPP---VPPPPPYLASYPGFPENGAPGPPISR 853
P P P + P+ +A + S P VPP PP AS P P A PP +
Sbjct: 675 --APFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPP--ASPPMSPS--ATPPPQAP 727
Query: 854 FPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGP 913
PL P + P PP S ++ TPPP+ PP L P + P +
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRV-PPLLAAPPLQVPPS---PPASLPMSPLAK 783
Query: 914 PPPRRESRTET---RWGPRPGSSRRGIPPEEPGA---------PPRRAGPIKKPPPPTKV 961
PPP+ T + P P +S G P P A PP +A P+ P
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 962 EELPPKPLEQGDETPKPPKPDPL----KITKGKLGGPKETP---PNGNLSPAPRLRRDYS 1014
P P Q P P PD ++T GP P P+ LS P L S
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSS 902
Query: 1015 YERVGPTSCRGRGRG 1029
P RG G
Sbjct: 903 SATSTPEELRGYDSG 917
Score = 113 bits (282), Expect = 2e-24
Identities = 135/466 (28%), Positives = 173/466 (37%), Gaps = 100/466 (21%)
Query: 500 PDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP------PASAPTPET--------- 544
P + L + P +P A P APP L APP+PP P + P+P+
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 545 -EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE-PQLPSKEGPEPP 602
P P +PP Q+ +P A+P VS + S + S A P++ P P P P
Sbjct: 662 QAPFSPPPSPPVQAPFSP--PASPP-VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 603 EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQH 662
PPP PP P P P + PPS P + PP + LL
Sbjct: 719 SATPPPQAPP-PLAAP------PLQVPPSPPASPPMSPSATPP----PRVPPLL------ 761
Query: 663 QWQQHQQGSAPPTPVPPSPPQ--PVTLGAVPAPQAPP----------PPPKALYPGALGR 710
+APP VPPSPP P++ A P PQAPP P P A +PG
Sbjct: 762 --------AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813
Query: 711 PP----PMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSS 766
P PM P+ P PP + LLQ P P P+ PR G +S
Sbjct: 814 SPSASLPMSPLATPP--PQAPPVLAAPLLQVPP-----SPPASPTLQAPRRPPTPGPDTS 866
Query: 767 EPFDRHAPAMLRERGTPP--------VDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDD 818
R A+ PP P LA T+TP E R D
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-----------D 915
Query: 819 KGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPP-----GSDEV 873
G PPP LA+ + P PP++ PG PLPWPP +D +
Sbjct: 916 SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF--RGAPG-APLPWPPATGPGSADGL 972
Query: 874 AKI-QTPPPKKEPPKEETAQLTGPE---AGRKPARGVGSGGQGPPP 915
I +T P+ P GP +G K A G G+G P
Sbjct: 973 CTIYETEGPESATPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSP 1017
Score = 111 bits (277), Expect = 9e-24
Identities = 266/1112 (23%), Positives = 358/1112 (32%), Gaps = 186/1112 (16%)
Query: 1113 HESDLAPSDKEAPTPKE---GTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
++ D A + A TP G LT P P P P +PA R G V + + R
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGR-KPLAER 61
Query: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPS----KEPLKEKLIPGPLSPVARG- 1224
G GG P+ P P + + P P S + P + PGP+S R
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 1225 GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAP 1284
G+ +G + R + + P R R + + + G PS PA A
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMAR 178
Query: 1285 GPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPV 1344
A T V + P P +A P ++ + +E S
Sbjct: 179 RSRAAGTEVGL-PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---------------- 221
Query: 1345 LLTPKAVGTPGGGGGGAVPG----------ISAMSRGDLSQRAKDLSKRSFSSQRPGMER 1394
P A P GGG P +S+ +R S R + S +P +
Sbjct: 222 ---PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 1395 QNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRP-----PEERPPG 1449
R P + + G P P R P P N + P P P
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 1450 LPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGG----HPRHKPGLPQ 1505
PLP PPS SA L Q + S PA + A S + AP P P
Sbjct: 339 TPLPLAPPSPSAPPSL-QTLPSPPA-TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 1506 APQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP 1565
+P +P P + + L S P + + +PR + P + PP
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGS-PTLQATHSFLTM---SPRQTQASLTSPSRPASTPP 452
Query: 1566 RKPELLQEESLP--PPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSY 1623
P L SLP PP + + P LT H L + S
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSP-----------LTIHPLQALSSLASHSPQ 501
Query: 1624 RPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGP 1683
P S M PL +A + + P S + P L A P
Sbjct: 502 APLS-SLIMPPLETQSSLAPPSLQ---------------TPPASLTTPPLENLPSLA--P 543
Query: 1684 PKRPGGSSPLNAVPCEGPPGSEP-PRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTD 1742
P S+PL E PP P P + PP+P E P PP +
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 1743 RGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELL 1802
+G P+ P P P +A L +A P L
Sbjct: 604 QGLPSPPLSPLATPPP---------------------QAPPXLALPPLQAPPSPPASPPL 642
Query: 1803 PSAAASAEPQSKNLDSGHCV-----PEPSSSGQRLY-----PEVFYGSAGPSSSQISGGA 1852
S A+ PQ+ N + H + P PS Q + P V + PS + S A
Sbjct: 643 -SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701
Query: 1853 MDSQLHPNSGGFRPGTPSLHP-------YRSQPLYLPPGPAPPSALLSGLALKGQFLDFS 1905
Q+ P+ P +PS P + PL +PP P P S +S A +
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-PASPPMSPSATPPPRVP-P 759
Query: 1906 TMQATELGKLPAGGVLYPPPSFLYSPAFCPSP-LPDTSLLQVRQDLPSPSDFYSTPLQPG 1964
+ A L P+ PP S SP P P P Q LPSP P
Sbjct: 760 LLAAPPLQVPPS-----PPASLPMSPLAKPPPQAPPALATPPLQALPSP------PASFP 808
Query: 1965 GQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVR 2024
GQ+ F PS + LPM P P APP PL +P P P A R
Sbjct: 809 GQAPFSPSAS------LPMSPLATPP------PQAPPVLAAPLLQVPPSPPASPTLQAPR 856
Query: 2025 PPPAPATRVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGP-------GSSRTP 2077
PP P S R +L P P SS L GP ++ TP
Sbjct: 857 RPPTPGPDTSVSGPR-LTLALAPGPPPPPSRSP-------SSTLSGPDLAGHSSSATSTP 908
Query: 2078 PTGRSF-SGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALR---WIPKPW-ERTGPP- 2131
R + SG A+P + + + +PP A R P PW TGP
Sbjct: 909 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 968
Query: 2132 --------PREGPSRRAEEPGSRGDKEPGLPP 2155
EGP PG+ +PG P
Sbjct: 969 ADGLCTIYETEGPESATPAPGA---LDPGPSP 997
Score = 101 bits (252), Expect = 7e-21
Identities = 171/676 (25%), Positives = 227/676 (33%), Gaps = 108/676 (15%)
Query: 386 PTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYP--DRGG-------PP 436
P + T RPP G P P PP+ P G G G P +R G P
Sbjct: 17 PAARAPGLLTPRPP----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAA----------- 485
P A R S S ERA + + RA+
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132
Query: 486 ----CAEKLKRLDEKFGAPDKR-LKAEPAAPPAAPSTPAPPPAVPKELPAP------PAP 534
AE+ + AP + L A + P+ P PA+ + A P P
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 535 PPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
P++ P P TE + + ++ + T AA S GG +S S +S P
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 595 SKEGPEPPEEVPPPTTPPVPKVEPKG-DGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQE 653
++ GP P P PK PKG + P + P + P +L P
Sbjct: 253 ARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAP----ALGPLSSSPLAT 306
Query: 654 QLLKQQQQHQWQQHQQGSAP-PTPVPPSPPQPVTLG-AVPAPQAPP-----PPPKALYPG 706
+ + P P +PPSPP L A P+P APP P P A P
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 707 ALGRPPPM--PPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGS 764
PP M PPM P IPP P L P L P P L + + S GS
Sbjct: 367 Q--APPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAPP---SPLALSSLQATTSLGS 420
Query: 765 ----SSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKG 820
++ F +P + T P P +TP + PL +PL A +
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRP---------ASTPPDSPPLQAPLSLPASPPLQ- 470
Query: 821 MRSETPPVPPPPPYLASYP----GFPENGAPGPPISRF---PLEEP---GPRPLPWPPGS 870
S +P V P L +P + +P P+S PLE P L PP S
Sbjct: 471 -TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 871 DEVAKIQTPPPKKEPP-KEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPR 929
++ P PP + +A LT P P Q PP P ET
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC-PAPCPLQAPPSPLTTPPPET----- 583
Query: 930 PGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKG 989
P PP +A P PP + P PL TP P P L +
Sbjct: 584 ---------PSSIATPPPQAPPALASPPLQGLPSPPLSPL----ATPPPQAPPXLALP-- 628
Query: 990 KLGGPKETPPNGNLSP 1005
P + PP+ SP
Sbjct: 629 ----PLQAPPSPPASP 640
Score = 99.4 bits (246), Expect = 3e-20
Identities = 255/1139 (22%), Positives = 366/1139 (32%), Gaps = 218/1139 (19%)
Query: 865 PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPA--RGVGSGGQGPPP------P 916
P PPGS PPP P G GRKP R G GG P P
Sbjct: 27 PRPPGSPR------PPPPVTPAALRVLGAAGA-VGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 917 RRESRTETRW-GPRPGSSRRG--IPPEEPGAP-----PRRAGPIKKPPP----------- 957
R + T +R RP +S RG PP + +P P RA +P P
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 958 ----PTKVEELPPKPL-----EQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008
K E P + + P P P P + + G + P S PR
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 1009 LRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG 1068
+ + V S AR R G GG R A SR S R G
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAG--GGLQRPA-SRSLSSSATPLSSPARSG 256
Query: 1069 GTG-----GPNHP--PAPRGRTASETRSEGSEYEEI-----PKRRRQRGSETGSETHESD 1116
+ P HP P P+G A ++ P + + S T
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 1117 LAPSDKEAPTPKEGTL-------TQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
+ P D A TP TL T +PLAPP P APPS + +PS
Sbjct: 317 VPPPDNAA-TPLPATLPPSPPLATPLPLAPPSPSAPPSL---------------QTLPS- 359
Query: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG--PLPPSKEP--LKEKLIPGPLSPVARGG 1225
PP P +PP+ + P + P +PP + P L + P SP+A
Sbjct: 360 --------PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Query: 1226 SNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPG 1285
+++G + F + + A+ S +P+ T P S P
Sbjct: 412 LQATTSLGSPTLQATHS--------------FLTMSPRQTQASLTSPSRPASTPPDSPP- 456
Query: 1286 PEEALTTVTVAPAPRRAAAKSPDLSNQNSD------QANEEWETASESSDFTSERRGDKE 1339
+++ +P + SP +S +S QA + S + +S E
Sbjct: 457 ---LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 1340 -----APPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMER 1394
APP + P ++ TP + + +++ L + L+ + P
Sbjct: 514 TQSSLAPPSLQTPPASLTTP------PLENLPSLAPPPLQTASAPLTTPHLET--PPCPA 565
Query: 1395 QNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDK--RSWPSP--KNRSRPPEERPPGL 1450
P + + P + P + PSP + PP + PP L
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625
Query: 1451 PLPP--PPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQA-- 1506
LPP PPS A L + +P L Q + P P P P A
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL--QAPFSPPPSPPVQAPFSPPASP 683
Query: 1507 PQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPR 1566
P PS PP++ P L P PM P+ ++ P + PP
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 1567 KPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPS 1626
P + + PPP L + P P P+
Sbjct: 744 SPPM-SPSATPPPRVPPLLAAPPLQVPPSP----------------------------PA 774
Query: 1627 SMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKR 1686
S+ P+SP +++ P SP G A P
Sbjct: 775 SL-----PMSPLAKPPP------------QAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 1687 PGGSSPLNAVPCEGPPG-SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGT 1745
SPL P + PP + P + PP+P + PR P P GP + R
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRLTLAL 876
Query: 1746 EPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSA 1805
PGP P PP + +S + G L S E + R ++ P
Sbjct: 877 APGP------PPPPSRSPSST-------LSGPDLAGHSSSATSTPEEL---RGYDSGPEG 920
Query: 1806 AASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAG---PSSSQISGGAMDSQLHP-NS 1861
A+A P + + C P S G P F G+ G P G+ D +
Sbjct: 921 GAAASPPP-DAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIYET 978
Query: 1862 GGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV 1920
G TP+ P L PGP+P ++ A G + + LG+LP G +
Sbjct: 979 EGPESATPA-------PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 1030
Score = 90.9 bits (224), Expect = 1e-17
Identities = 227/957 (23%), Positives = 297/957 (31%), Gaps = 192/957 (20%)
Query: 1264 RENAARGSEGKPSLTLPASAP--GPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
R+ A + G T+P SAP GP + T + PA R A+
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG---------------- 98
Query: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLS 1381
RG++ APP +P V +PG G PG + + L A++
Sbjct: 99 -------------RGER-APPAKNTSPGPVSSPGRASGTTRPG--PLGQKGLRISAEETV 142
Query: 1382 KRSFSSQRP-------GMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWP 1434
R +++ P G R P PG + + S G G P
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG----------LPRP 192
Query: 1435 SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQ-ALAQLSSRQGSVTAP 1493
+P R RPP E P S++ + S G+Q+ A LSS +++P
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 1494 GGHPRHKPGLPQAPQGPS-PRP-------PTRYEPQRVNSG-----LSSDPHFEEPGPMV 1540
G P+AP PS P+P P + P R ++ LSS P P P
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSG 311
Query: 1541 RGVGGTPRDSAGVSPFPPKRRERPPRKPEL-LQEESLPPPHSSGFLGSKPEGPGPQAESR 1599
P +P P PP L L S P S L S P P QA
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Query: 1600 DTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFE---DVAGTEMSQSDSGVDLS 1656
T TP P P ++ + P + + + S + LS
Sbjct: 372 MT-----TP----------------PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
Query: 1657 GDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHD 1716
+S G P S L P + P RP P D
Sbjct: 411 SLQATTS-----------------LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 1717 GDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRP--------SHRPGPPVQFGTSDKD 1768
+ P P P P+ T S + P I P SH P P
Sbjct: 454 SPPLQAPLSLPASP-PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP--------- 503
Query: 1769 SDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQ----SKNLDSGHCVPE 1824
L ++ L+ + L + P S L + + A P S L + H
Sbjct: 504 --LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 1825 PSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPG 1884
P + L + P + S Q P P L PL PP
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS--PPLQGLPSPPLSPLATPPP 619
Query: 1885 PAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSL- 1943
APP L L PP S SP PSP +L
Sbjct: 620 QAPPXLALPPLQAPPS----------------------PPASPPLSPLATPSPQAPNALA 657
Query: 1944 --LQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQ---------MLLPMVDSQLPVVN 1992
L P PS P P PS P Q + +P P ++
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 1993 FGSLPP--APPP-APPPLSLLPVGPALQPPSLAVRPPP-------APATRVLPSPARPFP 2042
+ PP APPP A PPL + P PA P S + PPP AP +V PSP P
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP----P 773
Query: 2043 ASLGRAELH--PVELKPFQDYQKLSSNLGGPGS-SRTPPTGRSFSGLNSRLKATPSTYSG 2099
ASL + L P + P L + P S P S S S L P
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833
Query: 2100 VFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156
V L Q P A + P PP GP P PG PPP
Sbjct: 834 VLAAP---LLQVPPSPPASPTLQAPRR----PPTPGPDTSVSGPRLTLALAPGPPPP 883
Score = 87.0 bits (214), Expect = 2e-16
Identities = 193/819 (23%), Positives = 263/819 (32%), Gaps = 155/819 (18%)
Query: 1429 DKRSWPSPKNRSRPPEERPPGLPLP-------PPPPSSSAVFRLDQVIHSNPAGIQQALA 1481
+KR +R P R PGL P PPPP + A R V+ + A ++ LA
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALR---VLGAAGAVGRKPLA 59
Query: 1482 QLSSRQGSVTAPGGHPRHKP--GLPQAPQGPSPRPPTRYEPQRVNSGLSSDP-------- 1531
+ + G T P PR P + + P+ RPP +R ++ P
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
Query: 1532 --HFEEPGPM-------------VRG-----------VGGTPRDSAGVSPFPPK----RR 1561
PGP+ RG G RD++G +P P RR
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRK 1621
R E LP P S P P E + + H A R
Sbjct: 180 SRAAG-----TEVGLPRPAPSA-------RPRPPTEGPRKSVSSASEHSTTEPSPAARR- 226
Query: 1622 SYRPSSMEPWMEPLSPFEDVAGTEMSQ-SDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAA 1680
RPS+ P S + T +S + SG G + + P + L+
Sbjct: 227 --RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 1681 EGPPKRPGGSS--PLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPG-PIGTER 1737
PP++ + PL++ P P S RP P P D P LPP P+ T
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP---DNAATPLPATLPPSPPLAT-- 339
Query: 1738 SQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSR 1797
P P+ P PP + S+ + IP +
Sbjct: 340 ---------PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ 390
Query: 1798 DWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQL 1857
L S + A P L S S L + + P +Q S + S
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQAT--TSLGSPTLQATHSFLTMSPRQTQAS---LTSPS 445
Query: 1858 HPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQ-----ATEL 1912
P S TP P PL LP P ++L ++ L +Q A+
Sbjct: 446 RPAS------TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS 499
Query: 1913 GKLPAGGVLYPP--------PSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPL-QP 1963
+ P ++ PP P L +P P+ L L + P P S PL P
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSLQTP---PASLTTPPLENLPSLAPPPLQTASAPLTTP 556
Query: 1964 GGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAP-------------PPLSLL 2010
++ P+ P Q P+ P S+ PP AP PPLS L
Sbjct: 557 HLETPPCPAPCPLQAPPSPLTTP--PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 2011 PVGPALQPPSLAV----RPPPAPATRVLPSPARPFPASLGRAELH----PVELKPFQDYQ 2062
P PP LA+ PP PA+ L A P P + +H P P Q
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 2063 KLSSNLGGP--GSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRW 2120
S P S TPP+ S L+ PS ASPP +
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS--------------PPASPPMSPSA 720
Query: 2121 IPKPWERTGPPPREGPSRRA--EEPGSRGDKEPGLPPPR 2157
P P PPP P + P S PPPR
Sbjct: 721 TPPP---QAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756
Score = 86.7 bits (213), Expect = 2e-16
Identities = 211/888 (23%), Positives = 288/888 (32%), Gaps = 154/888 (17%)
Query: 1336 GDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQ 1395
G PPPV TP A+ G G A+ R L++RA + + P
Sbjct: 31 GSPRPPPPV--TPAALRVLGAAG--------AVGRKPLAERAGGIGGATIPESAP----- 75
Query: 1396 NRRPGPGGKAGSSGSS-------SGGG-------GGGPGGRTGPGRGDKRSWPSPKN--- 1438
R GP AG+S + SG G PG + PGR + P P
Sbjct: 76 --RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 1439 -RSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHP 1497
R E G P S+ + P A+A+ S G+
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT-------- 185
Query: 1498 RHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFP 1557
+ GLP+ PRPPT + V+S +S+ EP P R R SAG
Sbjct: 186 --EVGLPRPAPSARPRPPTEGPRKSVSS--ASEHSTTEPSPAARR-----RPSAGGGLQR 236
Query: 1558 PKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTA 1617
P R L P S P P ++ + G +AL P
Sbjct: 237 PASRSLSSSATPLSS-----PARSGPSARGTPRAPAHPSQPKPKGLQALRPP-----QVT 286
Query: 1618 TSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLK 1677
RK P+ PL+ +GT+ + + + P ++P
Sbjct: 287 PPRKDAAPALGPLSSSPLAT-PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 1678 GAAEGPPKRPGGSSPLNAVPCEGPPG-SEPPRRPPPAPHDGDRKELPREQP-----LPPG 1731
+ PP SP P + PP + PP + PP+ ++P PP
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
Query: 1732 PIGTERSQRTDRGTEP---------------------GPIRPSHRP--GPPVQFGTSDKD 1768
P+ Q T P P RP+ P PP+Q S
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS--- 462
Query: 1769 SDLRLVVGDSLKAEKELTASVTEAI-PVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSS 1827
L A L S++ A+ P+S + P A S+ P+
Sbjct: 463 ----------LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHS--------PQAPL 504
Query: 1828 SGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLH----PYRSQPLYLPP 1883
S + P S P S Q ++ + N P P L P + L PP
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP--PPLQTASAPLTTPHLETPP 562
Query: 1884 GPAP------PSALLSGLALKGQFLDFSTMQATE-LGKLPAGGVLYPPPSFLYSPAFCPS 1936
PAP PS L + + QA L P G+ PP S L +P P
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP---PP 619
Query: 1937 PLPDTSLLQVRQDLPSPSDFYSTPLQP-GGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGS 1995
P L Q PSP S PL P S P+ + P P V
Sbjct: 620 QAPPXLALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ--- 674
Query: 1996 LPPAPPPAPPPLSLLPVGPALQPPSLAVRP---PPAPATRVLPSP-ARPFPASLGRAELH 2051
P PPA PP+S P+ PPSLA P PP+P SP A P P +
Sbjct: 675 -APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 2052 PVELKPFQDYQKLSSNLGGPGS-SRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQ 2110
P+++ P S P S S TPP L+ PS + + +
Sbjct: 734 PLQVPP-------SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 2111 QASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEP-GLPPPR 2157
QA P A P + PP P + P + P PPP+
Sbjct: 787 QAPPALA----TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830
Score = 70.1 bits (170), Expect = 2e-11
Identities = 153/679 (22%), Positives = 208/679 (30%), Gaps = 139/679 (20%)
Query: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
P P L SL+A P + T + +Q Q+ S + PP+S PL A +
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLT-MSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
Query: 117 PASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAA 176
++ P + +P +PL QA + +H SSL+ P L+
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI-------MPPLETQ 515
Query: 177 GDQDKAAKERESAEQSSGP---GPSLRPQNSTT---------WRDGGGRGPDELEGPDSK 224
+ + A ++ P PSL P T P L+ P S
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
Query: 225 LHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPP----PYGPQGPYRYPTPDGPS 280
L + PP P PP PP L PP P P P P P P
Sbjct: 576 L------------TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP- 622
Query: 281 RFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLK 340
P +A P PP P P + + +
Sbjct: 623 --PXLALPPLQAPPSPPASPPLSPLATPSPQ----------------APNALAVHLLQAP 664
Query: 341 FSDEEDGRDSDEEGAEGHRDSQSASGEERPP-EADGKKGNSPNSEPPTPKTAWAETSRPP 399
FS + S S PP +A P PP+P A P
Sbjct: 665 FSPPP---SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP---ASPPMSP 718
Query: 400 ETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSE 459
P P AP P PP + P P P PP PP A + S
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL-----LAAPPLQVPPSPP 773
Query: 460 ISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAA-PPAAPSTP 518
SL + + + + P + L + PA+ P AP +P
Sbjct: 774 ASLPMSPLAKPPPQAPPALAT------------------PPLQALPSPPASFPGQAPFSP 815
Query: 519 -APPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTS 577
A P P P P APP +AP + P PA +P Q+ P T VSG
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTPGPDTSVSG----- 869
Query: 578 STSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP 637
P+L P PP PPP+ P + GP G+
Sbjct: 870 -------------PRLTLALAPGPP---PPPSRSPSSTLS------GPDL------AGHS 901
Query: 638 KYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPP 697
S P ++ + +G A +P PP PA +
Sbjct: 902 SSATSTP--------------EELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRG 943
Query: 698 PPPKALYPGALGRPPPMPP 716
P P + GA G P P PP
Sbjct: 944 PAPPLAFRGAPGAPLPWPP 962
Score = 69.7 bits (169), Expect = 3e-11
Identities = 123/522 (23%), Positives = 173/522 (33%), Gaps = 103/522 (19%)
Query: 501 DKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPT 560
+KR KA+ A P+ AP P+ +P PPP + A +
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 561 PGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKG 620
G+ A S + + S+G+ +P S G P P T P P P G
Sbjct: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSP-G 118
Query: 621 DGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS 680
G TR P LG + S R + + K+ ++ ++ PTP PS
Sbjct: 119 RASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGA--RRDTSGPTPGTPS 173
Query: 681 PPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP 740
P A P P P A RPP P + + + P
Sbjct: 174 PAMARRSRAAGTEVGLPRPA----PSARPRPPTEGPRK------SVSSASEHSTTEPSPA 223
Query: 741 LDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
P G + R S S SS+ P A + RGTP A P
Sbjct: 224 ARRRPSA---GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-----------PAHP 269
Query: 801 AEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPG-PPISRFPLEEP 859
++P+P KG+++ PP PP ++ AP P+S PL P
Sbjct: 270 SQPKP-------------KGLQALRPPQVTPP---------RKDAAPALGPLSSSPLATP 307
Query: 860 GP-----RPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPP 914
P RP+P P + TP P PP + P A P PP
Sbjct: 308 SPSGTKARPVPPPDNA------ATPLPATLPP-------SPPLATPLPL--------APP 346
Query: 915 PPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPP---PTKVEELPPKPLEQ 971
P +T P P PP +A P PP P ++ +PP +
Sbjct: 347 SPSAPPSLQTL-------------PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393
Query: 972 GDETPK---PPKPDPLKITKG--KLGGPKETPPNGNLSPAPR 1008
+P PP P L + LG P + L+ +PR
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Score = 56.6 bits (135), Expect = 3e-07
Identities = 95/342 (27%), Positives = 119/342 (34%), Gaps = 61/342 (17%)
Query: 1117 LAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA----------PARFTARGGRVFTPRGV 1166
LA + P +L PLA PPP APP+ A PA F G F+P
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP--GQAPFSPSA- 817
Query: 1167 PSRRGRGGGRPPPQVCPGW---------SPPAKSL--APKKPPT-GPLPPSKEP-LKEKL 1213
S PPPQ P SPPA AP++PPT GP P L L
Sbjct: 818 -SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 876
Query: 1214 IPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEG 1273
PGP P +R S+ S + G + P +E G EG
Sbjct: 877 APGPPPPPSRSPSSTLSGPDLA----------GHSSSATSTP------EELRGYDSGPEG 920
Query: 1274 KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTS- 1332
A++P P+ L A R A P L+ + + A W A+
Sbjct: 921 G-----AAASPPPDAELAACHPAAWSRGPA---PPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 1333 ----ERRGDKEA-PPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSS 1387
E G + A P P L P GG A G A SR R +L + +
Sbjct: 973 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQA 1032
Query: 1388 Q--RPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGR 1427
+ + R G AG SG GG G GG TG R
Sbjct: 1033 SVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEG--GGVTGGAR 1072
Score = 46.6 bits (109), Expect = 3e-04
Identities = 92/365 (25%), Positives = 112/365 (30%), Gaps = 69/365 (18%)
Query: 93 SDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAH 152
S P S S + P SQ P+ P P PPA+P P+ PS QA A
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP---PMSPSATPP-PQAPPPLAA- 732
Query: 153 GDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGG 212
P LQ + SA P P + P +
Sbjct: 733 ------------------PPLQVPPSPPASPPMSPSAT----PPPRVPPLLAA------- 763
Query: 213 RGPDELEGPDSKLHHGHDPRGGLQPSGPPQF--PPYRGM-MPPFMYPPYLPFPPPYG-PQ 268
P P P P PP PP + + PP +P PF P P
Sbjct: 764 --PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821
Query: 269 GPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPV----GRPSILKEDNLKEFDQLDQENDD 324
P P P P P +A P PP P RP D +L
Sbjct: 822 SPLATPPPQAP---PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 325 GWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSE 384
G S G D GH S +++ EE G +G + S
Sbjct: 879 GPPPPPSRSP-------SSTLSGPD-----LAGHSSSATSTPEELRGYDSGPEGGAAASP 926
Query: 385 PPTPK------TAWAETSRPPETEPGPPAPKPPLP-PPHRGPAGNWGPPGDYPDRGGPPC 437
PP + AW+ PP G AP PLP PP GP G Y + GP
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRG--APGAPLPWPPATGPGSADGLCTIY-ETEGPES 983
Query: 438 KPPAP 442
PAP
Sbjct: 984 ATPAP 988
Score = 45.8 bits (107), Expect = 5e-04
Identities = 64/225 (28%), Positives = 76/225 (33%), Gaps = 35/225 (15%)
Query: 380 SPNSEPP--TPKTAWAETSRPPETEPGPPAPKPPLPPPHRGP-AGNWGPPGDYPDRGGPP 436
SP + PP P A + P + P P + P PP GP GP GPP
Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496
P + SSS S EE R A
Sbjct: 882 PPPSRSPSSTLSGPDLAGHSSSATS---------TPEELRGYDSGPEGGAAAS------- 925
Query: 497 FGAPDKRLKAEPAAPPAAPSTPAPP------PAVPKELPAPPAPPPASAPTPET--EPEE 548
PD L A P A PAPP P P LP PPA P SA T E E
Sbjct: 926 -PPPDAELAA--CHPAAWSRGPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYETEG 980
Query: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQL 593
P A PA PG + SGG + + +G+ SP + +L
Sbjct: 981 PESATPAPGALDPGPSPG---TSGGKAAAGAGAGASSRSPKQARL 1022
Score = 43.5 bits (101), Expect = 0.002
Identities = 65/271 (23%), Positives = 88/271 (32%), Gaps = 30/271 (11%)
Query: 58 PPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQ---SDPKSSDASTAQPPESQPLPAS 114
PP +P + P+ + P+ A+ Q S P S S P Q PA
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 115 QTPASNQPKRPPAA-PENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTL 173
TP PPA+ P P PS + + A L S PTL
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
Query: 174 QAA------GDQDKAAKERESAEQSSGPGP--SLRPQNSTTWRDGGGRGPDELEGPDSKL 225
QA G + R + + GP P S P ++ + D G P+
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 226 HHGHDPRGGLQPSGPPQFPP--------YRGMMPPFMY----PPYLPFPPPYGPQGPYRY 273
+ P GG S PP RG PP + LP+PP GP
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP------ 966
Query: 274 PTPDGPSRFPRVAGPRGSGPPMRLVEPVGRP 304
+ DG GP + P ++P P
Sbjct: 967 GSADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 38.5 bits (88), Expect = 0.072
Identities = 68/309 (22%), Positives = 103/309 (33%), Gaps = 65/309 (21%)
Query: 55 RMPPPANLPSLK----AENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQP 110
R PPP +L+ A G P L + G + +S P++ +A S
Sbjct: 34 RPPPPVTPAALRVLGAAGAVGRKP---LAERAGGIGGATIPESAPRAGPTRSAGT--SSR 88
Query: 111 LPASQTPASNQPKRPPAAPENT-----------------PLVPSGVKSWAQASVTHGAHG 153
PAS+ PAS + +R P A + PL G++ A+ +V G
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 154 DGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSS--GPGPSLRP---------- 201
+ + S+L + R+ A + R + + P PS RP
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 202 -----QNSTT----------WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPY 246
++STT GG + P S R G G P+ P +
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 247 ---------RGMMPPFMYPPYLPFPPPYGP--QGPYRYPTPDGPSRFPRVAGPRGSGPPM 295
+ + PP + PP P GP P P+P G P V P + P+
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARP-VPPPDNAATPL 327
Query: 296 RLVEPVGRP 304
P P
Sbjct: 328 PATLPPSPP 336
Score = 35.8 bits (81), Expect = 0.47
Identities = 67/321 (20%), Positives = 104/321 (32%), Gaps = 52/321 (16%)
Query: 5 SGPTAKGKDGKKYSSLNLFDTY-KGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLP 63
SG T G G+K ++ +T +GK+ E AP+ S G P P
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATE------APKRSALSAGARRDTSGPTPGTPSP 174
Query: 64 SLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPK 123
++ ++ V L P+ + ++ +PP P + + + +
Sbjct: 175 AMARRSRAAGTEVGL----------------PRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 124 RPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDK-- 181
P A P G++ A S++ A +S S S P A Q K
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATP---LSSPARSGPSARGTPRAPAHPSQPKPK 275
Query: 182 ---AAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPS 238
A + + P+L P +S+ P P P
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSS---------PLATPSPSGTKARPVPPPDNAATP 326
Query: 239 GPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMR-- 296
P PP PP P LP PP P P P+ P A P + PPM+
Sbjct: 327 LPATLPP----SPPLATP--LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 297 ----LVEPVGRPSILKEDNLK 313
+ P+ P L +L+
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQ 401
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 122 bits (306), Expect = 4e-27
Identities = 334/1344 (24%), Positives = 434/1344 (32%), Gaps = 252/1344 (18%)
Query: 535 PPASAPTPETEPEE---PAQAPPAQSTPTPGV-------AAAPTLVSGGGSTSSTSSGSF 584
P + +P+ +P P P PTPG + P L
Sbjct: 241 PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKG 300
Query: 585 EASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQ-GL-------GY 636
E + +EP + EGP PE PP + P G R PP + GL G
Sbjct: 301 EPAVLEPGM-LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGP 359
Query: 637 PKYQKSLPPRFQRQQQEQ---LLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAP 693
P LP RF ++ + Q+ Q Q Q A PP P+ P P
Sbjct: 360 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR-----GPPGPMGYTGRPGP 414
Query: 694 QAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFY-----PPGV 748
P P G G P P P+ + PP R +GR D PGV
Sbjct: 415 LGQPGSPGL--KGESGDLGPQGPRG--PQGLTGPPGKAGR--RGRAGADGARGMPGDPGV 468
Query: 749 HPS----GL--VPRE---RSDSG-----GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGD 794
GL +P E R D+G G E +R + RG P +G
Sbjct: 469 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528
Query: 795 VFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRF 854
P P P P + D S P P PP PG G PGP +
Sbjct: 529 --KGPPGIPGP---PGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPG--TQGLPGPQGAIG 581
Query: 855 PLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQ-LTGPEA-----GRKPARGVGS 908
P E GP+ P PG P K+ PP + Q +GP+ G + +GV
Sbjct: 582 PHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDG 641
Query: 909 -----GGQGPPPPRRESRTETRWGPRPGSSRRGIP----PEEPGAPPRRAGPIKKPPPPT 959
G +G + G + G+P + P P R GP P PP
Sbjct: 642 IRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 701
Query: 960 KVEE-----LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYS 1014
+ E +P P G + PK G LG P +G +
Sbjct: 702 LMGEKGKLGVPGLPGYPGRQGPK-----------GSLGFPGFPGASGEKGARGLSGKSGP 750
Query: 1015 YERVGPTSCRGRGRGEYFARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG-- 1071
GPT RG+ RG A G+ G +GT GG G E RG G G G
Sbjct: 751 RGERGPTGPRGQ-RGPRGATGKSGAKGTSGGDGPHGPPGE-------RGLPGPQGPNGFP 802
Query: 1072 GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGT 1131
GP PP P G+ + +P QRG E G + P P G
Sbjct: 803 GPKGPPGPPGK------------DGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGE 849
Query: 1132 LTQV-----PLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPG 1184
+ P P PPG P A G P G P + G G G P + PG
Sbjct: 850 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP-GAPGKDGPAGLRGFPGERGLPG 908
Query: 1185 WSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRR 1243
+ L + P+GP PGP SP RG + G +G
Sbjct: 909 -TAGGPGLKGNEGPSGP-------------PGPAGSPGERGAAGSGGPIGPP-------- 946
Query: 1244 RHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAA 1303
GR Q P E G G+ + P PGP
Sbjct: 947 --GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP----------------- 987
Query: 1304 AKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAV 1362
A P ++ ++ D+ E T +G+ P PP + P VG PG G
Sbjct: 988 AGPPGVAGEDGDKG----EVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGE 1041
Query: 1363 PGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGR 1422
PG +G + D R F+ PG PGP G+ G +G G GP G
Sbjct: 1042 PGARG-PQGHFGAKG-DEGTRGFNGP-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098
Query: 1423 TGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQ 1482
GP + N + P+ P G+ PP + S GIQ
Sbjct: 1099 RGP---------AGPNGADGPQGPPGGVGNLGPPGEKG------EPGESGSPGIQG---- 1139
Query: 1483 LSSRQGSVTAPGGHPRHK--PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM- 1539
+ V P G K G P P P P+ PT + + N G P +PGP
Sbjct: 1140 ----EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG--DPGPPG 1193
Query: 1540 ---VRGVGGTPRDSA-----GVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSK--- 1588
RG G D G P E P P L + P S G G K
Sbjct: 1194 EGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAK 1252
Query: 1589 -------------PEGP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEP 1634
P GP GP + G L + + + ++ P + P
Sbjct: 1253 GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--PG 1310
Query: 1635 LSPFEDVAGTEMSQSDSGV----------DLSGDSQVSSGPCSQRSSPDGGLKGAAE--- 1681
L AG + + G+ GD + S + G+ GA+
Sbjct: 1311 LPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG 1370
Query: 1682 --GPPKRPGGSSPLNAVPCEGP--PGSEPPRRPPPAPHDGDRKELPREQPLP-PGPIGTE 1736
GPP PG + P A GP P E + PP H G E+ QPLP P T
Sbjct: 1371 PGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG-HPGPPGEV--IQPLPIQMPKKTR 1427
Query: 1737 RSQRTDR-GTEPGPIRPSHRPGPP 1759
RS R E I PG P
Sbjct: 1428 RSVDGSRLMQEDEAIPTGGAPGSP 1451
Score = 108 bits (271), Expect = 4e-23
Identities = 334/1421 (23%), Positives = 439/1421 (30%), Gaps = 301/1421 (21%)
Query: 187 ESAEQSSGPGPSLRPQNSTTWRDGGG--RGPDELEGPDSKLHHGHDPRGGLQPS------ 238
E E G RPQN R + P L P ++ DP G +
Sbjct: 222 EQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSL 281
Query: 239 ---------GPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPR 289
GP +G P + P L PP GP+GP P G P G
Sbjct: 282 LPPLEEAAHGPRGLKGEKGE-PAVLEPGMLVEGPP-GPEGPAGLIGPPGIQGNPGPVGDP 339
Query: 290 GS-GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGR 348
G GPP R P G GA + L F G
Sbjct: 340 GERGPPGRAGLP------------------------GSDGAPGPPGTSLMLPFRFGSGGG 375
Query: 349 DSDEEGAEGHRDSQSASGEER-----PPEADGKKGN-SPNSEPPTPKTAWAETSRPPETE 402
D A +Q+ + R PP G G P +P +P + E
Sbjct: 376 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL---------KGE 426
Query: 403 PGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISL 462
G P+ P RGP G GPPG RG D + R L
Sbjct: 427 SGDLGPQGP-----RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP-GL 480
Query: 463 AVERARRRREEEERRM----QEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTP 518
E+ R + ++ R E R G P + P P P
Sbjct: 481 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPR-----GLPGESGPRGLLGPKGPPGIP 535
Query: 519 APPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSS 578
PP + + P P + P E P P Q P P A P G
Sbjct: 536 GPPGV--RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPH--GEKGPQGK 591
Query: 579 TSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP--PVPKVEPKG----DGI-GPTRQPPS 631
S P P KEGP + P+ P P+ P+G DGI G
Sbjct: 592 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 651
Query: 632 QGL-GYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAV 690
+G G+P ++ + + R E + + + +G PT P P G +
Sbjct: 652 KGEDGFPGFKGDIGVKGDRG--EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 709
Query: 691 PAPQAPPPPPKALYPGALGRPPPMPPMNFD-----------PRWMMIPP----YVDPRLL 735
P P P + G+LG P P + + PR P PR
Sbjct: 710 GVPGLPGYPGRQGPKGSLGFPG-FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768
Query: 736 QGRPPLDFYPPGVHPSGLVPRERSDSG--GSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
G+ G P G P ER G G + P + P + G P + VG
Sbjct: 769 TGKSGAKGTSGGDGPHG-PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG 827
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
P P + P A + G R P PP PP E G PG
Sbjct: 828 FQGKTGPPGPPGVVGPQGAAGETGPMGERGH--PGPPGPP--------GEQGLPGTAGKE 877
Query: 854 FPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP----------KEETAQLTGPEAGRKPA 903
+PGP P PG D A ++ P ++ P E + GP AG
Sbjct: 878 GTKGDPGP---PGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP-AGSPGE 933
Query: 904 RGV-GSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEE-PGAPPRR---AGPIKKPPPP 958
RG GSGG PP R + GP + +G+P E+ P P R GP+ P P
Sbjct: 934 RGAAGSGGPIGPPGRPGPQ-----GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPA 988
Query: 959 TKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERV 1018
P G++ K DP + KG G E P G P + + +
Sbjct: 989 GP-------PGVAGEDGDKGEVGDPGQ--KGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039
Query: 1019 GPTSCRGRGRGEYFARG----RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--- 1071
G RG +G + A+G RGF G G G + G G G TG
Sbjct: 1040 GEPGARGP-QGHFGAKGDEGTRGFNGPPGPIG----------LQGLPGPSGEKGETGDVG 1088
Query: 1072 --GPNHPPAPRGRTA--------------------------SETRSEGSEYEEIPKRRRQ 1103
GP PP PRG E+ S G + E K R
Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148
Query: 1104 RGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTP 1163
E G + P + PT +G P P G P P P GG P
Sbjct: 1149 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGN----PGPVGFPGDPGPP---GEGG----P 1197
Query: 1164 RGVPSRRG-RGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKE--------KLI 1214
RG +G RG P Q PG P P P G P+ P E K
Sbjct: 1198 RGQDGAKGDRGEDGEPGQ--PGSPGPTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAKGD 1254
Query: 1215 PGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGK 1274
PG + + G G + + G R G QQ +P A G G
Sbjct: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP------------GATGQAGP 1302
Query: 1275 PSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSER 1334
P P PG A + P L +
Sbjct: 1303 PGPVGPPGLPGLR--------GDAGAKGEKGHPGLIGLIGPPGEQG-------------E 1341
Query: 1335 RGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMER 1394
+GD+ P P G+PG G +PG S G + PG+
Sbjct: 1342 KGDRGLPGPQ-------GSPGQKGEMGIPGAS----GPIGPGGP-----------PGL-- 1377
Query: 1395 QNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPP 1454
PGP G G+ G++ G GGP G G P PP E LP+
Sbjct: 1378 ----PGPAGPKGAKGAT---GPGGPKGEKGV--------QGPPGHPGPPGEVIQPLPIQM 1422
Query: 1455 PPPS-----SSAVFRLDQVIHS-----NPAGIQQALAQLSS 1485
P + S + + D+ I + +P G+++ L S
Sbjct: 1423 PKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDS 1463
Score = 103 bits (256), Expect = 2e-21
Identities = 295/1223 (24%), Positives = 389/1223 (31%), Gaps = 251/1223 (20%)
Query: 640 QKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS--------PPQPVTLGAVP 691
Q P R QR Q+Q + H+ Q + S PTP PP
Sbjct: 237 QNQQPHRAQRSPQQQ---PSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPR 293
Query: 692 APQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVD-------------PRLLQGR 738
+ P L PG L PP P P ++ PP + P G
Sbjct: 294 GLKGEKGEPAVLEPGMLVEGPPGPE---GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 350
Query: 739 PPLDFYPPGVHPSGLVPRERSDSGGSSSEPF----DRHAPAMLRE-----RGTP------ 783
P D PG + L+ R SGG P + A A+L++ RG P
Sbjct: 351 PGSDG-APGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 409
Query: 784 --------PVDPKLAWV-GDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPY 834
P P L GD+ P P+ LT P +A G ++ P P
Sbjct: 410 GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG--ADGARGMPGDPG 467
Query: 835 LASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSD-EVAKIQTPPPKKEPPKEETAQL 893
+ GF +G PG P + + G + LP PPG D E P+ P + L
Sbjct: 468 VKGDRGF--DGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525
Query: 894 TGPEA--GRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSS----RRGIP-PEEPGAPP 946
GP+ G GV G GP P+ + GP PG +G+P P+ P
Sbjct: 526 LGPKGPPGIPGPPGV-RGMDGPQGPKGSLGPQGEPGP-PGQQGTPGTQGLPGPQGAIGPH 583
Query: 947 RRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-P 1005
GP KP LP P G P P + TKG G + P G L P
Sbjct: 584 GEKGPQGKPG-------LPGMPGSDGP--PGHPGKEGPPGTKGNQG---PSGPQGPLGYP 631
Query: 1006 APRLRRDYSYERVGPTSCRGRGRGEYFARG-RGFRGTYGGRGRGARSREFRSYREFRGDD 1064
PR + G +G +GE G GF+G G +G R RG+D
Sbjct: 632 GPRGVKGVD----GIRGLKGH-KGEKGEDGFPGFKGDIGVKG----DRGEVGVPGSRGED 682
Query: 1065 GRGGGTG--GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSE-----TGSETHESDL 1117
G G G GP P P G + + P R+ +GS G+ +
Sbjct: 683 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742
Query: 1118 APSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFT-----PRGVPSRRGR 1172
S K P + G P G P T + G T P G P RG
Sbjct: 743 GLSGKSGPRGERG----------PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG- 791
Query: 1173 GGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNV 1232
PG P PK PP PP K+ L P P RG V
Sbjct: 792 ---------LPGPQGPNGFPGPKGPPG---PPGKDGL-------PGHPGQRG------EV 826
Query: 1233 GMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTT 1292
G + G G P + P A G
Sbjct: 827 GFQ-------------------------------GKTGPPGPPGVVGPQGAAGE------ 849
Query: 1293 VTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVG 1352
P R P + + T+ + G K P P P A G
Sbjct: 850 --TGPMGERGHPGPPGPPGE-------------QGLPGTAGKEGTKGDPGP----PGAPG 890
Query: 1353 TPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSS 1412
G G PG + L + G E + PGP G G G++
Sbjct: 891 KDGPAGLRGFPG------------ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 938
Query: 1413 GGGGGGPGGRTG----PGRGDKRSWPSPKN----RSRPPEERPPGLPLPPPPPSSSAVFR 1464
GG GP GR G PG ++ P K R + P GLP P PP +
Sbjct: 939 SGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDG 998
Query: 1465 LDQVIHSNPAGIQQALAQLSSRQGSVTAPGG-HPRHKPGLPQAPQGPSPRPPTRYEPQRV 1523
D+ +P Q+ G PG P +PG A P R P + +
Sbjct: 999 -DKGEVGDPG--QKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055
Query: 1524 NSGLSSDPHFEEPGPM----VRGVGGTPRDSAGVSPFPPKRRERP--PRKPELLQEESLP 1577
+ G PGP+ + G G ++ V P P P P P P
Sbjct: 1056 DEGTRG--FNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113
Query: 1578 P--------------PHSSGFLGSKPE----GP-GPQAESRDTGTEALTPHIWNRLHTAT 1618
P P SG G + E GP G + E ++G + T
Sbjct: 1114 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD 1173
Query: 1619 SRKSYRPSSMEPWMEPLSPFE-DVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLK 1677
P + +P P E G + ++ D G D S GP + + P G L
Sbjct: 1174 DGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE-NGPPGPL- 1231
Query: 1678 GAAEGPPKRPGGSSPLNAVPCEGPPGS--EPPRRPPPAPHDGDRKELPREQPLPPGPIGT 1735
GP PG +G PG+ P + P P K P PG +G
Sbjct: 1232 -GKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQ 1290
Query: 1736 E-RSQRTDRGTEPGPIRPSHRPG 1757
+ R T + PGP+ P PG
Sbjct: 1291 QGRPGATGQAGPPGPVGPPGLPG 1313
Score = 97.1 bits (240), Expect = 2e-19
Identities = 323/1365 (23%), Positives = 427/1365 (31%), Gaps = 257/1365 (18%)
Query: 345 EDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP---------------- 388
E G+ + + HR +S +++P + P S+ PTP
Sbjct: 229 EGGQRERPQNQQPHRAQRSP--QQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLE 286
Query: 389 ------KTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPG--------DYPDRGG 434
+ E P EPG PP P GPAG GPPG P G
Sbjct: 287 EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP---EGPAGLIGPPGIQGNPGPVGDPGERG 343
Query: 435 PPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLD 494
PP + P + + + L ++ +E +A + RL
Sbjct: 344 PPGRAGLPGSDGAP-----GPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 398
Query: 495 EKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELP-APPAPPPASAPTPETEPEEPAQAP 553
+ G P P P +P P P P + P + A A
Sbjct: 399 LR-GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 457
Query: 554 PAQSTP-TPGVA------AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVP 606
A+ P PGV P L G T + P E +G P +P
Sbjct: 458 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 517
Query: 607 PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQK-SLPPRFQRQQQEQLLKQQQQHQWQ 665
+ P + PKG G P +G+ P+ K SL P Q
Sbjct: 518 GESGPR-GLLGPKGPP-GIPGPPGVRGMDGPQGPKGSLGP--------------QGEPGP 561
Query: 666 QHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMM 725
QQG+ P T P P + PQ P P PG+ G PP P P
Sbjct: 562 PGQQGT-PGTQGLPGPQGAIGPHGEKGPQGKPGLPG--MPGSDG-PPGHPGKEGPPGTKG 617
Query: 726 IPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPV 785
P+ G P P GV + + G + F P + G
Sbjct: 618 NQGPSGPQGPLGYPG----PRGVKGVDGIRGLKGHKGEKGEDGF----PGFKGDIGVKGD 669
Query: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPP----------PPYL 835
++ G P P+ T P D G+ E + P P
Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGP---TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 726
Query: 836 ASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG 895
+PGFP GA G +R + GPR P G P + P+ T
Sbjct: 727 LGFPGFP--GASGEKGARGLSGKSGPRGERGPTG----------PRGQRGPRGAT----- 769
Query: 896 PEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP-PEEPGAPPRRAGPIKK 954
G+ A+G SGG GP P PG RG+P P+ P P GP K
Sbjct: 770 ---GKSGAKGT-SGGDGPHGP-------------PG--ERGLPGPQGPNGFP---GP-KG 806
Query: 955 PPPPTKVEELPPKPLEQGDE--TPKPPKPDPLKITKGKLGGPKETPPNGNLS-PAPRLRR 1011
PP P + LP P ++G+ K P P + G G ET P G P P
Sbjct: 807 PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV-GPQGAAGETGPMGERGHPGP---- 861
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG 1071
GP +G +G G G G+ + R + RG G GG G
Sbjct: 862 ------PGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA-GLRGFPGERGLPGTAGGPG 914
Query: 1072 -----GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPT 1126
GP+ PP P G + E + GS P R G+ + PT
Sbjct: 915 LKGNEGPSGPPGPAG-SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973
Query: 1127 PKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTP--RGVPSRRG-RGGGRPPPQVCP 1183
++G Q P+ P P PP A G V P +G +G G PP + P
Sbjct: 974 GRDG--VQGPVGLPGPAGPPGVAGE--DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP 1029
Query: 1184 GWSPPAKSLAPKKPPTGPL----------------PPSKEPLKEKLIPGPLSPVARGGSN 1227
P A + GP PP P+ + +PGP G
Sbjct: 1030 VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG--PIGLQGLPGPSGEKGETGDV 1087
Query: 1228 GGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPE 1287
G G R +G Q P L E G G P + PG
Sbjct: 1088 GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI---QGEPG-- 1142
Query: 1288 EALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLT 1347
K P ++ + E + G K P PV
Sbjct: 1143 ----------------VKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF- 1185
Query: 1348 PKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGK--- 1404
P G PG GG G ++GD + + S PG +N PGP GK
Sbjct: 1186 PGDPGPPGEGGPRGQDG----AKGDRGEDGEPGQPGS-----PGPTGENGPPGPLGKRGP 1236
Query: 1405 AGSSGSSSGGGG----GGPG-----GRTGP-GRGDKRSWPSPK----------NRSRPPE 1444
AGS GS GG G PG G+TGP G P P + RP
Sbjct: 1237 AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGA 1296
Query: 1445 ERPPGLPLPPPPPSSSAVFRLD-----QVIHSNPAGIQQALAQLSSR-QGSVTAPGGHPR 1498
G P P PP + R D + H G+ + + + P G P
Sbjct: 1297 TGQAGPPGPVGPPGLPGL-RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPG 1355
Query: 1499 HK--PGLPQA--PQGPSPRP--PTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
K G+P A P GP P P P+ E G V+G G P
Sbjct: 1356 QKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG--VQGPPGHPGPPGE 1413
Query: 1553 V-SPFP---PKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPG 1593
V P P PK+ R L+QE+ P G P PG
Sbjct: 1414 VIQPLPIQMPKKTRRSVDGSRLMQEDEAIP------TGGAPGSPG 1452
Score = 92.0 bits (227), Expect = 5e-18
Identities = 280/1149 (24%), Positives = 360/1149 (31%), Gaps = 238/1149 (20%)
Query: 211 GGRGPDELEG-PDSKLHHGHDPRGGLQPSGPPQFPPYRG---MMPPFMYPPYLPFPPPYG 266
G RG D L G P K H G GL GPP RG + P P G
Sbjct: 470 GDRGFDGLPGLPGEKGHRGDTGAQGLP--GPPGEDGERGDDGEIGPRGLPGESGPRGLLG 527
Query: 267 PQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGW 326
P+GP P P G GP+GS P P G+ L G
Sbjct: 528 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL--------PGPQGA 579
Query: 327 AGAHEEVDYTEK-----LKFSDEEDGRDSDEEGAEGHRDSQSASGEERP---PEADGKKG 378
G H E K + SD G +EG G + +Q SG + P P G KG
Sbjct: 580 IGPHGEKGPQGKPGLPGMPGSDGPPGHPG-KEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638
Query: 379 ----------NSPNSEPPTP--------KTAWAETSRP-PETEPGPPAPK-------PPL 412
E P K E P E GP PK P
Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698
Query: 413 PPPHRGPAGNWGPPG--DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRR 470
PP G G G PG YP R GP P + + + S + R
Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK-----SGPRGE 753
Query: 471 REEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPA 530
R R Q R A K GA P PP P P P P
Sbjct: 754 RGPTGPRGQRGPRGATG--------KSGAKGTSGGDGPHGPPGERGLPGPQG--PNGFPG 803
Query: 531 PPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
P PP P + P P Q G P +V G+ T P
Sbjct: 804 PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 861
Query: 591 PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQ 650
P P ++G +P K +P G P + P+ G+P ++ LP
Sbjct: 862 PGPPGEQG------LPGTAGKEGTKGDPGPPG-APGKDGPAGLRGFPG-ERGLP------ 907
Query: 651 QQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ--------PVTLGAVPAPQAPPPPPKA 702
+ ++ S PP P SP + P+ P PQ PP A
Sbjct: 908 ------GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG--PPGAA 958
Query: 703 LYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
G G P+ P D +QG P+ P P V E D
Sbjct: 959 GEKGVPGEKGPIGPTGRDG-------------VQG--PVGLPGPAGPPG--VAGEDGDK- 1000
Query: 763 GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMR 822
G +P + E G P + VG A P + D+G R
Sbjct: 1001 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1060
Query: 823 SETPPVPPPPPYLASYPG----------FPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
PP P L PG G PGPP R P G PPG
Sbjct: 1061 GFNG--PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG-- 1116
Query: 873 VAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG----VGSGGQ----GPPPPRRESRTET 924
V + P K EP + + + G E G K RG G GQ GPP P+ + +
Sbjct: 1117 VGNLGPPGEKGEPGESGSPGIQG-EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD- 1174
Query: 925 RWGPR-----------PGSSRRGIPPEEPGA-----------PPRRAGPIKKPPPPTKVE 962
GP+ PG G P + GA P GP + PP +
Sbjct: 1175 --GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232
Query: 963 ELPP--KPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP 1020
+ P P +G + K K DP G +G P +T P G PA + GP
Sbjct: 1233 KRGPAGSPGSEGRQGGKGAKGDP-----GAIGAPGKTGPVGPAGPA---------GKPGP 1278
Query: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080
RG G+ G +GR G G+ G G P P
Sbjct: 1279 DGL------------RGLPGSVGQQGR-------------PGATGQAGPPGPVGPPGLPG 1313
Query: 1081 GRTASETRSEGSEYEEI-----PKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV 1135
R + + E I P + ++G P + +P K
Sbjct: 1314 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG---------LPGPQGSPGQKGEMGIPG 1364
Query: 1136 PLAPPPPGAPPS-PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAP 1194
P PG PP P PA +G + T G P +G G + PP PG PP + + P
Sbjct: 1365 ASGPIGPGGPPGLPGPA--GPKGAKGATGPGGP--KGEKGVQGPPG-HPG--PPGEVIQP 1417
Query: 1195 -----KKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG--GSNVGMEDGERPRRRRHGR 1247
K + S+ +++ IP +P + GG GS + + RR G
Sbjct: 1418 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTG- 1476
Query: 1248 AQQQDKPPR 1256
QD P R
Sbjct: 1477 --TQDSPAR 1483
Score = 90.5 bits (223), Expect = 2e-17
Identities = 310/1352 (22%), Positives = 425/1352 (31%), Gaps = 303/1352 (22%)
Query: 818 DKGMRSETPPVPPPPPYLASYPGFPENGAP-GPPISRFPLEE---PGPRPLPWPPGSDEV 873
+ GM E PP P P L PG N P G P R P PG P PPG+ +
Sbjct: 306 EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 365
Query: 874 AKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSS 933
+ G G G +GP +E++ + + +
Sbjct: 366 LPFRF--------------------------GSGGGDKGPVVAAQEAQAQAIL-QQARLA 398
Query: 934 RRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPK-PDPLKITKGKLG 992
RG P P R GP+ +P P E GD P+ P+ P L GK G
Sbjct: 399 LRG--PPGPMGYTGRPGPLGQPGSPGLKGE-------SGDLGPQGPRGPQGLTGPPGKAG 449
Query: 993 GPKETPPNG--NLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGAR 1050
+G + P ++ D ++ G G +G RG G +G
Sbjct: 450 RRGRAGADGARGMPGDPGVKGDRGFD--GLPGLPGE---------KGHRGDTGAQGLPGP 498
Query: 1051 SREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGS 1110
E RGDDG G G P PRG + IP RG + G
Sbjct: 499 PGEDGE----RGDDGEIGPRGLPGES-GPRGLLGPKGPPG------IPGPPGVRGMD-GP 546
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRR 1170
+ + L P + P ++GT PG P P G P+G P
Sbjct: 547 QGPKGSLGPQGEPGPPGQQGT----------PGTQGLPGPQGAIGPHGEK-GPQGKPGLP 595
Query: 1171 GRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGS 1230
G G PP PP K GP GP P+ G G
Sbjct: 596 GMPGSDGPPGHPGKEGPPGT-----KGNQGP-------------SGPQGPLGYPGPRGVK 637
Query: 1231 NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPE--E 1288
V DG R + G + +D P F+ + +G G+ + GPE +
Sbjct: 638 GV---DGIRGLKGHKGE-KGEDGFPGFKG-----DIGVKGDRGEVGVPGSRGEDGPEGPK 688
Query: 1289 ALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTP 1348
T T P P P L + K P + P
Sbjct: 689 GRTGPTGDPGP-------PGLMGEKG-----------------------KLGVPGLPGYP 718
Query: 1349 KAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSS 1408
G G G PG S + A+ LS +S G + GP G G S
Sbjct: 719 GRQGPKGSLGFPGFPGASG------EKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 772
Query: 1409 GSSSGGGGGGPGGRTG----PGRGDKRSWPSPKNRSRPP-EERPPGLPL----------- 1452
G+ GG GP G G PG +P PK PP ++ PG P
Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 832
Query: 1453 -PPPPP-------SSSAVFRLDQVIHSNPAGI--QQALAQLSSRQGSVTAPGGHPRHKPG 1502
PP PP ++ + + H P G +Q L + ++G+ + PG
Sbjct: 833 GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT--------KGDPG 884
Query: 1503 LPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFE-EPGPM-VRGVGGTP--RDSAGVS-PFP 1557
P AP P + +R G + P + GP G G+P R +AG P
Sbjct: 885 PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIG 944
Query: 1558 PKRRERPPRKPELLQEESLP-------PPHSSGFLGSK----PEGP-GPQAESRDTGTEA 1605
P R P P E+ +P P G G P GP G E D G
Sbjct: 945 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 1004
Query: 1606 LTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFED-------------VAGTEMSQSDSG 1652
+ + P + P +P + D G E ++ +G
Sbjct: 1005 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1064
Query: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPP- 1711
Q GP ++ GPP G + P A +GPPG PP
Sbjct: 1065 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124
Query: 1712 ---------------------PAPHDGDRKELPRE-QPLPPGPIGTERSQRTDRGTE--P 1747
P G++ E + +P PPGP G D G + P
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG----DDGPKGNP 1180
Query: 1748 GPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAA 1807
GP+ PGPP + G +D GD D E P
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDG----AKGDR-----------------GEDGE--PGQPG 1217
Query: 1808 SAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPG 1867
S P +N P G+R G AG S+ G ++ P + G PG
Sbjct: 1218 SPGPTGEN-------GPPGPLGKR-------GPAGSPGSEGRQGGKGAKGDPGAIG-APG 1262
Query: 1868 TPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSF 1927
P GPA P+ L+G L S Q G+ A G PP
Sbjct: 1263 KTG-----------PVGPAGPAGKPGPDGLRG--LPGSVGQQ---GRPGATGQAGPPGP- 1305
Query: 1928 LYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPG--GQSGFL-PSGAPAQQMLLPMV 1984
P P D + + P P + G G G P G+P Q+ + +
Sbjct: 1306 -VGPPGLPGLRGDAG-AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1363
Query: 1985 DSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPP---PAPATRVLPSPARPF 2041
+ P + G P P PA P + GP V+ P P P V+ +P
Sbjct: 1364 GASGP-IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI----QPL 1418
Query: 2042 PASLGRAELHPVELKPFQDYQKLSSNLGGPGS 2073
P + + V+ + G PGS
Sbjct: 1419 PIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS 1450
Score = 60.8 bits (146), Expect = 1e-08
Identities = 160/658 (24%), Positives = 198/658 (30%), Gaps = 112/658 (17%)
Query: 105 PPESQPLPASQTPASNQ-PKRPPAAP--ENTPLVPS-----GVKSWAQASVTHGAHGDGG 156
PP + LP Q P PK PP P + P P G + G G G
Sbjct: 786 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 845
Query: 157 RASSLLSRFSREEFPTLQAAGDQD---KAAKERESAEQSSGPGPSLRPQNSTTWRDG--- 210
A R G+Q A KE + PGP P +DG
Sbjct: 846 AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD----PGPPGAPG-----KDGPAG 896
Query: 211 -----GGRG-PDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPP 264
G RG P GP K + G P G P+G P G P + PP P
Sbjct: 897 LRGFPGERGLPGTAGGPGLKGNEG--PSGPPGPAGSPGERGAAGSGGP-IGPPGRP---- 949
Query: 265 YGPQGPYRYPTPDGPSRFPRVAGPRGSGP------PMRLVEPVGRPSILKEDNLK-EFDQ 317
GPQGP P G P GP G P+ L P G P + ED K E
Sbjct: 950 -GPQGP---PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005
Query: 318 LDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD-EEGAEGHRDSQSASGEERPPEADGK 376
Q+ G G H + + +D E GA G + A G+E +G
Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065
Query: 377 KGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPP 436
G P P ET + GP P P PP RGPAG G G GG
Sbjct: 1066 PGPIGLQGLPGPSGEKGETG-----DVGPMGP--PGPPGPRGPAGPNGADGPQGPPGGVG 1118
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496
P P ++ E E + R R + E
Sbjct: 1119 NLGP-PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES--------------------- 1156
Query: 497 FGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKEL--PAPPAPPPASAPT----------PE 543
G P EP P P P+ P P + P P PP P +
Sbjct: 1157 -GQP-----GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1210
Query: 544 TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE 603
EP +P P PG GS + P P K GP P
Sbjct: 1211 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP- 1269
Query: 604 EVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
P P + +G +P + G P PP + + K ++ H
Sbjct: 1270 -AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG-PPGLPGLRGDAGAKGEKGHP 1327
Query: 664 WQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP------PKALYPGALGRPPPMP 715
G PP +P PQ P P A P G PP +P
Sbjct: 1328 GLIGLIG-------PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1378
Score = 56.2 bits (134), Expect = 3e-07
Identities = 147/610 (24%), Positives = 191/610 (31%), Gaps = 108/610 (17%)
Query: 1238 ERPRRRRHGRAQQ--QDKPPRFRRLKQERENAARGSEGKPSLTLPAS--------APGPE 1287
ERP+ ++ RAQ+ Q +P R R + + + + G+ L +S A GP
Sbjct: 234 ERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPR 293
Query: 1288 ------------EALTTVTVAPAPRRAAAK-SPDLSNQNSDQANEEWETASESSDFTSER 1334
E V P P A P N + E
Sbjct: 294 GLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGS 353
Query: 1335 RGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMER 1394
G P L+ P G+ GG G V A ++ L Q L PG
Sbjct: 354 DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP------PGPMG 407
Query: 1395 QNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPP 1454
RPGP G+ GS G G GP G GP +G R R + G+P P
Sbjct: 408 YTGRPGPLGQPGSPGLKGESGDLGPQGPRGP-QGLTGPPGKAGRRGRAGADGARGMPGDP 466
Query: 1455 PPPSSSAVFRLDQVI----HSNPAGIQQALAQLSSRQGSVTAPGG-HPRHKPGLPQ---- 1505
L + H G Q L G G PR PG
Sbjct: 467 GVKGDRGFDGLPGLPGEKGHRGDTGAQ-GLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525
Query: 1506 -APQGPS--PRPPT---RYEPQRVNSGLSSDPHFEEPGPMVR----GVGGTPRDSAGVSP 1555
P+GP P PP PQ L EPGP + G G P + P
Sbjct: 526 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG---EPGPPGQQGTPGTQGLPGPQGAIGP 582
Query: 1556 FPPKRRERPPRKPELLQEESLP-------PPHSSGFLG-SKPEGP----GPQAESRDTGT 1603
K + P P + + P PP + G G S P+GP GP+ G
Sbjct: 583 HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGI 642
Query: 1604 EALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSS 1663
L H E + F+ G + + + GV S
Sbjct: 643 RGLKGH-----------------KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 685
Query: 1664 GPCSQRSSPDG-----GLKG-----AAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPP- 1712
GP R+ P G GL G G P PG P ++ G PG+ +
Sbjct: 686 GP-KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 744
Query: 1713 APHDGDRKEL----PREQPLPPGPIGTERSQRTDRGTEP----------GPIRPSHRPGP 1758
+ G R E PR Q P G G ++ T G P GP P+ PGP
Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804
Query: 1759 PVQFGTSDKD 1768
G KD
Sbjct: 805 KGPPGPPGKD 814
Score = 52.4 bits (124), Expect = 5e-06
Identities = 98/418 (23%), Positives = 137/418 (32%), Gaps = 93/418 (22%)
Query: 96 KSSDASTAQPPESQPLPASQTPA----SNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151
++ D PP P + PA ++ P+ PP N L P G K S + G
Sbjct: 1083 ETGDVGPMGPPGP---PGPRGPAGPNGADGPQGPPGGVGN--LGPPGEKGEPGESGSPGI 1137
Query: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGG 211
G+ G R + E G + + + PGP P + +GG
Sbjct: 1138 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN-PGPVGFPGDPGPPGEGG 1196
Query: 212 GRGPDELEG----------PDSKLHHGHD----PRGGLQPSGPPQFPPYRGMMPPFMYPP 257
RG D +G P S G + P G P+G P +G P
Sbjct: 1197 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1256
Query: 258 YLPFPP---PYGPQGPYRYPTPDGPSRFPRVAGPRG-------SGPPMRLVEPVGRPSIL 307
+ P P GP GP P PDG P G +G +GPP PVG P +
Sbjct: 1257 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP----GPVGPPGL- 1311
Query: 308 KEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGE 367
G G + GA+G + G
Sbjct: 1312 ----------------PGLRG-----------------------DAGAKGEKGHPGLIGL 1332
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPP--HRGPAGNWGP 425
PP G+KG+ P E P + P P P LP P +G G GP
Sbjct: 1333 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1392
Query: 426 PGDYPDRG--GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEE 481
G ++G GPP P P + + + + + + RR + R MQE+
Sbjct: 1393 GGPKGEKGVQGPPGHPGPPGEVIQ-----------PLPIQMPKKTRRSVDGSRLMQED 1439
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 122 bits (305), Expect = 5e-27
Identities = 169/648 (26%), Positives = 244/648 (37%), Gaps = 121/648 (18%)
Query: 409 KPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERAR 468
KP PP +GP + ++ PP KPP RK+ +++ E +
Sbjct: 10435 KPKAPP--KGP--------EISEKIIPPKKPPTKVVP-------RKEPPAKVP---EVPK 10474
Query: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPS---TPAPPPAVP 525
+ EE+ R+ EE R + + L K P+K++ PA P AP AP VP
Sbjct: 10475 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP 10534
Query: 526 -KELPAPPAPPPASAPT--PET------EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGST 576
K++P PP P PT PE E + P PP +P P V AP V
Sbjct: 10535 EKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKV 10594
Query: 577 SSTSSGSFEASPVE-PQLPSKEGPEPPEEVPPPTTPPVP--KVEPKGDGIGPTRQPPSQG 633
+ E +PV+ P+ P + PE VPPP P VP KV P ++ P
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE-- 10652
Query: 634 LGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLG-AVPA 692
P +S PP + +E L++ ++ + + P VPP P P AV A
Sbjct: 10653 -AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVA 10711
Query: 693 PQAPPPP-----------PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
+ PP P+ P + + P PP +P V P P
Sbjct: 10712 KKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE----VPKEVVPEKKVAVPKK 10767
Query: 742 DFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPA 801
PP P VP++ +L E+ PV + P
Sbjct: 10768 PEVPPAKVPE--VPKK-----------------PVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 802 EPRPLTSPLRQAADEDDKGM---RSETPPVPPP----------PPYLASYPGFPENGAPG 848
E +P + A E++K + E P VPPP P PE P
Sbjct: 10809 E----IAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPK 10864
Query: 849 PPISRFPLEEP--GPRPLPWPPG------SDEVAKIQTPPPKKEPPK---EETAQLTGPE 897
P +E+P PRP P PP +++ +++ P KK P K E +LT +
Sbjct: 10865 EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLK 10924
Query: 898 --AGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKP 955
G K R + + P P+ E ++ RP EEP P++ +KKP
Sbjct: 10925 VPGGEKKVRKLLP--ERKPEPKEEVVLKSVLRKRP-------EEEEPKVEPKKLEKVKKP 10975
Query: 956 PPPTKVEELPPKPLEQGDETPKPPK-----PDPLKITKGKLGGPKETP 998
P E PPKP+E+ E P K P+P K+ + K P P
Sbjct: 10976 AVP---EPPPPKPVEE-VEVPTVTKRERKIPEPTKVPEIKPAIPLPAP 11019
Score = 118 bits (296), Expect = 5e-26
Identities = 163/664 (24%), Positives = 236/664 (35%), Gaps = 114/664 (17%)
Query: 367 EERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPP 426
E++ P KK E P PK A PE + P PK P PP + P P
Sbjct: 10507 EKKVPVPPAKK-----PEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE---VPK 10558
Query: 427 GDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAAC 486
P++ P PP PE + K+ E + ++ E ++ E +
Sbjct: 10559 AAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPA-APPKKPEVTPVKVPEAPKEVV 10617
Query: 487 AEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEP 546
EK + P K+ + P P P P VP+ +P P PP P EP
Sbjct: 10618 PEKKVPV-----PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPP---PEVFEEP 10669
Query: 547 EEPA-QAPPAQSTPTPGVAAAPTL-VSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEE 604
EE A + PPA+ P AA P + V + + A +P+LP + PE P+E
Sbjct: 10670 EEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK--KPELPPVKVPEVPKE 10727
Query: 605 VPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQW 664
V P VP V PK P + P P+ + ++P
Sbjct: 10728 VVP--EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP-------------------- 10765
Query: 665 QQHQQGSAPPTPVPPSPPQPV--TLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPR 722
++ PP VP P +PV AVP P+ PP +Y P P
Sbjct: 10766 ---KKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYE---------EPEEIAPE 10813
Query: 723 WMMIPPYVDPRLLQGRPPLDFYPPGV--HPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
+ P P + + PP V P ++P ++ P + +
Sbjct: 10814 EEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP--------------EKKVPVIKKPE 10859
Query: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
PP +P+ V + P P P +P ++ D +K + + P P P
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKE--DVKEKIFQLKAIPKKKVP----EKPQ 10913
Query: 841 FPENGAPGPPISRFPLEEPG---------PRPLPWPPGSDEVAKIQTPPPKKEPPKEETA 891
PE + PL+ PG P P P + + P++E PK E
Sbjct: 10914 VPEK------VELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPK 10967
Query: 892 QLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP-----PEEPGAPP 946
+L E +KPA PPPP+ E P R IP PE A P
Sbjct: 10968 KL---EKVKKPA------VPEPPPPKPVEEVEV---PTVTKRERKIPEPTKVPEIKPAIP 11015
Query: 947 RRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE--TPPNGNLS 1004
A P KP P +V+ + P P+E P P+ K + PKE P G +
Sbjct: 11016 LPA-PEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK 11074
Query: 1005 PAPR 1008
P+
Sbjct: 11075 GVPK 11078
Score = 107 bits (268), Expect = 1e-22
Identities = 136/547 (24%), Positives = 200/547 (36%), Gaps = 102/547 (18%)
Query: 474 EERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP--STPAPPPAVPKELPAP 531
E+ R++EE R EK+ R+ E F A + + +P APP P S PP P P
Sbjct: 10405 EQHRVEEEHRV---EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVP 10461
Query: 532 PAPPPASAPTPETE---------PEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSG 582
PPA P + PEEP + PP T P V +V
Sbjct: 10462 RKEPPAKVPEVPKKIVVEEKVRVPEEP-RVPP---TKVPEVLPPKEVVP---------EK 10508
Query: 583 SFEASPVE-PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQP--PSQGLGYPKY 639
P + P+ P + PE P+EV P PVP PK + PT+ P P + K
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPP--PKKPEVPPTKVPEVPKAAVPEKKV 10566
Query: 640 QKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP 699
+++PP+ + E + + P VP +PP+ + V P+AP
Sbjct: 10567 PEAIPPKPESPPPEV----------PEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP--- 10613
Query: 700 PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERS 759
K + P + P+PP P+ +PP P + P P P + P+ S
Sbjct: 10614 -KEVVPE---KKVPVPP----PKKPEVPPTKVPEV-----PKVAVPEKKVPEAIPPKPES 10660
Query: 760 DSGGSSSEPFD---RHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADE 816
EP + PA + E P P++ T P +P P ++
Sbjct: 10661 PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQV-------TVPPKKPVP---------EK 10704
Query: 817 DDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVA-- 874
+ ++ P +PP P P+ P + ++P P P EV
Sbjct: 10705 KAPAVVAKKPELPP-----VKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE 10759
Query: 875 -KIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPP----------PRRE-SRT 922
K+ P + PP + P KPA V + PPP P E +
Sbjct: 10760 KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPE 10819
Query: 923 ETRWGPRPGSSRRGIPPEEPGAPPRRAGP------IKKPPPPTKVEELPPKPLEQGDETP 976
E + P +PP P++ P IKKP P E P K +E+ P
Sbjct: 10820 EEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKP 10879
Query: 977 KPPKPDP 983
+PP P P
Sbjct: 10880 RPPPPPP 10886
Score = 85.9 bits (211), Expect = 4e-16
Identities = 185/809 (22%), Positives = 269/809 (33%), Gaps = 134/809 (16%)
Query: 237 PSGPPQFP--PYRGMMPPFMYPPYLPFPPPYGPQGPYRY-PTPDGPSRFPR-VAGPRGSG 292
P+ P+ P P P P + PP P+ P + P P+ P+ V P
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKV 10088
Query: 293 PPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDE 352
P R EPV P L ++ F++ EE E+ + EE+ +E
Sbjct: 10089 PKKR--EPVPVPVALPQEEEVLFEE---------EIVPEEEVLPEEEEVLPEEEEVLPEE 10137
Query: 353 EGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL 412
E + EE PPE + P E P E PE +P P P P
Sbjct: 10138 EEVLPEEEEIPPEEEEVPPEEE----YVPEEEEFVP-----EEEVLPEVKPKVPVPAPVP 10188
Query: 413 PPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
+ P PP K PE + +R E L VE E
Sbjct: 10189 EIKKKVTEKKVVIP---KKEEAPPAK--VPEVPKKVEEKRIILPKEEEVLPVEVTE---E 10240
Query: 473 EEERRMQEERRAACAEKLKRLDEKFG--APDKRLKAEPAAP----------PAAPSTPAP 520
EE + EE ++ ++E P+ KA P AP PA S P
Sbjct: 10241 PEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP 10300
Query: 521 PPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQST-PTPGVAAAPTLVSGGGSTSST 579
VP + APP P+ PE+ P ++ P G VS
Sbjct: 10301 EEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVV 10360
Query: 580 SSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKY 639
E VE ++ +E PE E V + +G+ + +
Sbjct: 10361 VKERLELEVVEAEV--EEIPEEEE------FHEVEEYFEEGE--------------FHEV 10398
Query: 640 QKSLPPRFQRQQQE-------QLLKQQQQHQWQQHQQGSAPPTP-------VPPSPPQPV 685
++ + R ++E ++++ + + + ++ APP +PP P
Sbjct: 10399 EEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTK 10458
Query: 686 TLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP 745
+ P P PK + R P P +PP P +L PP + P
Sbjct: 10459 VVPRKEPPAKVPEVPKKIVVEEKVRVPEEP---------RVPPTKVPEVL---PPKEVVP 10506
Query: 746 PGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPR- 804
P VP + P AP + PV P P +P
Sbjct: 10507 EKKVP---VPPAKKPEAPPPKVP---EAPKEVVPEKKVPVPP------------PKKPEV 10548
Query: 805 -PLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRP 863
P P A +K + PP P PP P P+ P + P ++P P
Sbjct: 10549 PPTKVPEVPKAAVPEKKVPEAIPPKPESPP--PEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 864 LPWPPGSDEVA---KIQTPPPKKE--PPKE--ETAQLTGPEAGRKPARGVGSGGQGPPPP 916
+ P EV K+ PPPKK PP + E ++ PE +K + + PPP
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE--KKVPEAIPPKPESPPPE 10664
Query: 917 RRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKV-------EELPPKPL 969
E E P + EP APP+ P KKP P K ELPP +
Sbjct: 10665 VFEEPEEVALEEPPAEV---VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKV 10721
Query: 970 EQGDETPKPPKPDPLKITKGKLGGPKETP 998
+ + P K PL + K P + P
Sbjct: 10722 PEVPKEVVPEKKVPLVVPKKPEAPPAKVP 10750
Score = 80.9 bits (198), Expect = 1e-14
Identities = 144/652 (22%), Positives = 241/652 (36%), Gaps = 90/652 (13%)
Query: 34 QKPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQS 93
+KP V P + + K A+ + P A P ++ P V PK+ K +
Sbjct: 10544 KKPEVPPTK-VPEVPKAAVPEKKVPEAIPPKPESP----PPEVPEAPKEVVP-EKKVPAA 10597
Query: 94 DPKSSDASTAQPPES--QPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151
PK + + + PE+ + +P + P PK+P P P VP + + V
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVPVP-PPKKPEVPPTKVPEVPK--VAVPEKKVPEAI 10654
Query: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGG 211
+ E P + + ++ A E AE P P+ PQ +
Sbjct: 10655 P-------------PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTV------ 10695
Query: 212 GRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPY 271
P + P+ K + L P P+ P + ++P P +P P P
Sbjct: 10696 ---PPKKPVPEKKAPAVVAKKPELPPVKVPEVP--KEVVPEKKVPLVVPKKPEAPPAKVP 10750
Query: 272 RYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHE 331
P P + +VA P+ P V V + +L+E + + E
Sbjct: 10751 EVPKEVVPEK--KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPE 10808
Query: 332 EVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADG---KKGNSPNSEPPTP 388
E+ E++ +E+ ++EE E + ++ PE KK +P + P P
Sbjct: 10809 EIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868
Query: 389 KTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWG----PPGDYPDRGG-------PPC 437
+ + P+ +P PP P PP PP + P P++ P
Sbjct: 10869 E----KVIEKPKLKPRPPPP-PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPL 10923
Query: 438 KPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKF 497
K P E + RK E + R+R EEEE +++ ++ EK+K+
Sbjct: 10924 KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK----LEKVKKPAVPE 10979
Query: 498 GAPDKRLKAEPAAP---------PAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEE 548
P K ++ E P P P PA+P PAP P P E + +
Sbjct: 10980 PPPPKPVE-EVEVPTVTKRERKIPEPTKVPEIKPAIPL-----PAPEPKPKPEAEVKTIK 11033
Query: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPP 608
P PP + PTP AAP V G + + EA+ +P+ P K P++ P P
Sbjct: 11034 P---PPVEPEPTP--IAAPVTVPVVGKKAEAKAPKEEAA--KPKGPIK---GVPKKTPSP 11083
Query: 609 TTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660
K+ P G P + P + K++P +F ++ ++ +L + +
Sbjct: 11084 IEAERRKLRPGSGGEKPPDEAP-----FTYQLKAVPLKFVKEIKDIILTESE 11130
Score = 76.6 bits (187), Expect = 2e-13
Identities = 162/749 (21%), Positives = 249/749 (33%), Gaps = 169/749 (22%)
Query: 367 EERPPEADGKKGNSPNSEPPTPKTAWAETSRPP--ETEPGPPAPKPPLPPPHRGPAGNWG 424
EE+ ++ + P + P PK E +P + E PP PK P P P
Sbjct: 9382 EEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVA 9441
Query: 425 PPGDYPDRGGPP----CKPPAPEDE-------------------------DEAWRQRRKQ 455
P + PP K E++ +E W ++
Sbjct: 9442 VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501
Query: 456 SSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAA----- 510
+S++V R R EEEE + E E+ ++EK KR++AEPA
Sbjct: 9502 EG--VSISVYREEEREEEEEAEVTEYEVMEEPEEYV-VEEKLHIISKRVEAEPAEVTERQ 9558
Query: 511 ----------------PPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPP 554
PP A AP VP++ P P P P+ PEEP + P
Sbjct: 9559 EKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV-PEEPKKPVP 9617
Query: 555 AQSTPTPGV---AAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP--------- 602
+ P + P V+ + A + P PE P
Sbjct: 9618 EKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV 9677
Query: 603 -------EEVPPPTTPPVPKVEPKGDGI---GPTRQPP---------------------- 630
EE PP K K + + P R+P
Sbjct: 9678 LKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAV 9737
Query: 631 --SQGLGYPKYQKSLPPRFQRQQ------QEQLLKQQQQHQWQQHQQ-----------GS 671
+ Y +Y++ F+ + Q + ++++ ++++H++
Sbjct: 9738 SVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKP 9797
Query: 672 APPTPV---PPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPP 728
P PV P +PP V AVP + P P PK L P PPP P P
Sbjct: 9798 VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKP-----PPPKVPEE--------PK 9844
Query: 729 YVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRH--APAMLRERGTPPVD 786
V ++ P+ VP + P R AP + ++
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELE 9904
Query: 787 P-KLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE--TPPVPPPPPYLASYPGFPE 843
P ++A+ +V T L + E+++ + E P +P P + P PE
Sbjct: 9905 PEEVAFEEEVVTHV---EEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP-VPE 9960
Query: 844 NGAPGPPISRFPLEEPGPRPLPWPPGSDE------VAKIQTPPPKKEP--PK----EETA 891
P P + +E P +P P E + K + PPP K P PK EE
Sbjct: 9961 EKKPVPVPKK---KEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKV 10017
Query: 892 QLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEE-PGAPPRRAG 950
+ P+ P V + P P ++ P P + PP + P P +
Sbjct: 10018 PVPVPKKVEAPPAKVPEVPKKPVPEKKV--------PVPAPKKVEAPPAKVPEVPKKLIP 10069
Query: 951 PIKKPPP-PTKVEELPPKPLEQGDETPKP 978
KKP P P KVE PPK ++ + P P
Sbjct: 10070 EEKKPTPVPKKVEAPPPKVPKKREPVPVP 10098
Score = 73.9 bits (180), Expect = 2e-12
Identities = 158/728 (21%), Positives = 240/728 (32%), Gaps = 142/728 (19%)
Query: 22 LFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPK 81
+ + ++ + +E+ + AP G + I+ ++ PP P+ K V VPK
Sbjct: 10421 VIEVFEAEEVEVFEKPKAPPKGPE------ISEKIIPPKKPPTKVVPRKEPPAKVPEVPK 10474
Query: 82 DGTGWASKQEQSDPKSSDASTAQP-PESQPLPASQTPASNQPKRPPAAPENTPLVPSGVK 140
+ +P+ + P + +P + P K+P A P P P V
Sbjct: 10475 KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVP-PAKKPEAPPPKVPEAPKEVV 10533
Query: 141 SWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLR 200
+ V + E P + + KAA + ++ P P
Sbjct: 10534 PEKKVPVPPP---------------KKPEVPPTKVP-EVPKAAVPEKKVPEAIPPKPESP 10577
Query: 201 PQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPY-- 258
P P+ E P + P P P+ P + P P
Sbjct: 10578 P-------------PEVPEAPKEVVPEKKVPAA---PPKKPEVTPVKVPEAPKEVVPEKK 10621
Query: 259 LPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQL 318
+P PPP P+ P P P+VA P P +P P + E+
Sbjct: 10622 VPVPPPKKPEVP-----PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP------- 10669
Query: 319 DQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKG 378
EEV E EE + + + E++ P KK
Sbjct: 10670 ------------EEVALEEPPAEVVEEPEPAAPPQVTV---PPKKPVPEKKAPAVVAKKP 10714
Query: 379 NSPNSE-PPTPKTAWAETSRP---PETEPGPPAPKPPLPP---PHRG---PAGNWGPPGD 428
P + P PK E P P+ PPA P +P P + P PP
Sbjct: 10715 ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAK 10774
Query: 429 YPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAE 488
P+ P KP E +R + E+ E EEE +EE+ AE
Sbjct: 10775 VPE---VPKKPVLEEKPAVPVPERAESPPPEV---YEEPEEIAPEEEIAPEEEKPVPVAE 10828
Query: 489 KLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEE 548
+ EP PP P+ P P + E P P + P E EPE+
Sbjct: 10829 E----------------EEPEVPP--PAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPP 608
+ P + P P A P F+ + P+ E P+ PE+V
Sbjct: 10871 VIEKPKLKPRPPPPPPAPP--------KEDVKEKIFQLKAI-PKKKVPEKPQVPEKV-EL 10920
Query: 609 TTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQ 668
T VP E K + P R+P PK + L +++ +E+ K + + +
Sbjct: 10921 TPLKVPGGEKKVRKLLPERKPE------PKEEVVLKSVLRKRPEEEEPKVEPKK--LEKV 10972
Query: 669 QGSAPPTPVPPSP----------------PQPVTL----GAVPAPQAPPPPPKALYPGAL 708
+ A P P PP P P+P + A+P P AP P PK
Sbjct: 10973 KKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLP-APEPKPKPEAEVKT 11031
Query: 709 GRPPPMPP 716
+PPP+ P
Sbjct: 11032 IKPPPVEP 11039
Score = 72.4 bits (176), Expect = 4e-12
Identities = 115/459 (25%), Positives = 164/459 (35%), Gaps = 102/459 (22%)
Query: 584 FEASPVE----PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKY 639
FEA VE P+ P K GPE E++ PP PP V P ++PP++ PK
Sbjct: 10425 FEAEEVEVFEKPKAPPK-GPEISEKIIPPKKPPTKVV--------PRKEPPAKVPEVPK- 10474
Query: 640 QKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS-------PPQPVTLGAVPA 692
K + + + ++ PPT VP P + V +
Sbjct: 10475 -----------------KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKK 10517
Query: 693 PQAPPPP----PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV 748
P+APPP PK + P + P+PP P+ +PP P + + P P +
Sbjct: 10518 PEAPPPKVPEAPKEVVPE---KKVPVPP----PKKPEVPPTKVPEVPKAAVPEKKVPEAI 10570
Query: 749 HPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
P P P ++ PA PP P++ V P P+ +
Sbjct: 10571 PPKPESPPPEVPEAPKEVVP-EKKVPA------APPKKPEVTPV-----KVPEAPKEVVP 10618
Query: 809 PLRQAADEDDKGMRSETPP--VPPPPPYLASYPGFPENGAP---GPPISRFPLEEPGPRP 863
+ K E PP VP P PE P PP F EEP
Sbjct: 10619 EKKVPVPPPKK---PEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF--EEPEEVA 10673
Query: 864 LPWPPGSD-EVAKIQTPPPKKEPPKEETAQLTGPEA-GRKPARGVGSGGQGPPPPRRESR 921
L PP E + PP PPK+ + P +KP + PP E
Sbjct: 10674 LEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP--------ELPPVKVPEVP 10725
Query: 922 TETRWGPRPGSSRRGIPPEEPGAPPRR--------------AGPIKKPPPPTKVEELPPK 967
E P + P++P APP + A P K PP KV E+P K
Sbjct: 10726 KEVV----PEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKK 10781
Query: 968 PLEQGDETPKPPKPDPLKITKGKL-GGPKETPPNGNLSP 1005
P+ +E P P P+ + ++ P+E P ++P
Sbjct: 10782 PVL--EEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818
Score = 67.4 bits (163), Expect = 1e-10
Identities = 207/974 (21%), Positives = 318/974 (32%), Gaps = 197/974 (20%)
Query: 305 SILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSA 364
S+ +E+ +E+++ D + EE + TE+ + E+ + + E E H +
Sbjct: 9738 SVQREEEYEEYEEYDYKE-------FEEYEPTEE--YDQYEEYEEREYERYEEHEEY--I 9786
Query: 365 SGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWG 424
+ E+P ++P P + + P E P P PK PPP + P
Sbjct: 9787 TEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVP-VPIPKKLKPPPPKVPEE--- 9842
Query: 425 PPGDYPDR-----------------GGPPCKPPAPEDEDEAWRQRRKQSSS----EISLA 463
P + ++ P KP E++ R++ + E+
Sbjct: 9843 PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKE 9902
Query: 464 VERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPA 523
+E EEE EE E+ +E+F ++ + P P P P P
Sbjct: 9903 LEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEK 9962
Query: 524 VPKELPAPPAPPPASAPTPETEPEE--PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSS 581
P +P PPA P +PEE P P + P V
Sbjct: 9963 KPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKV------------------ 10004
Query: 582 GSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQK 641
P++P K P P E+VP P V K + P + P + + P +K
Sbjct: 10005 ---------PEVPKK--PVPEEKVPVPVPKKVEAPPAKVPEV-PKKPVPEKKVPVPAPKK 10052
Query: 642 -SLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVP-----PSPPQPVTLGAVPAPQA 695
PP + ++L+ ++++ PTPVP P P P VP P A
Sbjct: 10053 VEAPPAKVPEVPKKLIPEEKK------------PTPVPKKVEAPPPKVPKKREPVPVPVA 10100
Query: 696 PPPPPKALYPGALGRPPPMPPMNFDPRWMMIPP---YVDPRLLQGRPPLDFYPPGVHPSG 752
P + L+ + +P P + P V P + P + PP
Sbjct: 10101 LPQEEEVLFEEEI-----VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEE-- 10153
Query: 753 LVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQ 812
VP E E + E P V PK+ P P P +
Sbjct: 10154 -VPPE--------EEYVPEEEEFVPEEEVLPEVKPKV-------------PVPAPVPEIK 10191
Query: 813 AADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
+ K + + PP A P P+ I EE P + P +
Sbjct: 10192 KKVTEKKVVIPKKEEAPP-----AKVPEVPKK-VEEKRIILPKEEEVLPVEVTEEPEEEP 10245
Query: 873 VAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGS 932
+++ + P +EPP E + P + + P P + E+ P
Sbjct: 10246 ISEEEIP---EEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEA--------PPAK 10294
Query: 933 SRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLG 992
+ IP E+ P + KK PP KV E+P K E+ PK P K + L
Sbjct: 10295 VSKKIPEEKVPVPVQ-----KKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAK-GRTVLE 10348
Query: 993 GPKETPPNGNLSPAPRLRRDYSYERVG--PTSCRGRGRGEYFARGRGFRGTYGGRGRGAR 1050
+ RL + V P EYF G
Sbjct: 10349 EKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH-----------E 10397
Query: 1051 SREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGS 1110
EF + R ++ H R +E E E PK G
Sbjct: 10398 VEEFIKLEQHRVEE---------EHRVEKVHRVIEVFEAEEVEVFEKPK-----APPKGP 10443
Query: 1111 ETHESDLAPSDKEAPT---PKEGTLTQVP------------LAPPPPGAPPSPAPARFTA 1155
E E + P K+ PT P++ +VP P P PP+ P
Sbjct: 10444 EISEKIIPP--KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPP 10501
Query: 1156 RGGRVFTPRGVPSRRGRGGGRPPPQV--CPGWSPPAKSLAPKKPPTGP-LPPSKEP---- 1208
+ V + VP + PPP+V P P K + P PP P +PP+K P
Sbjct: 10502 K--EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV-PVPPPKKPEVPPTKVPEVPK 10558
Query: 1209 --LKEKLIPGPLSP 1220
+ EK +P + P
Sbjct: 10559 AAVPEKKVPEAIPP 10572
Score = 59.3 bits (142), Expect = 4e-08
Identities = 115/518 (22%), Positives = 189/518 (36%), Gaps = 97/518 (18%)
Query: 505 KAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
+ EP PP P P P P+E+ P P P P+ PE P + P + P P
Sbjct: 9281 RVEP--PPKVPELPEKP--APEEVAPVPIPKKVEPPAPKV-PEVPKKPVPEEKKPVPVPK 9335
Query: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP----PVPKVEPKG 620
P A P P++P K P P E++P P P KV
Sbjct: 9336 KEPA-----------------APPKVPEVPKK--PVPEEKIPVPVAKKKEAPPAKVPEVQ 9376
Query: 621 DGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS 680
G+ + + ++S PP ++++ ++++ ++ + P P P
Sbjct: 9377 KGVVTEEKITI----VTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK 9432
Query: 681 PPQPVTLGAVPAPQA-PPPPPKALYPGALGRPPPMPPMNF---DPRWMMIPPYVDPRLLQ 736
P P AVP P A PPP+A + + + F + +P V+ +
Sbjct: 9433 KPVPEEKVAVPVPVAKKAPPPRA----EVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHE 9488
Query: 737 GRPPLDF----YPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWV 792
++ GV S ER + + ++ ++ E V+ KL +
Sbjct: 9489 VSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYE-----VMEEPEEYVVEEKLHII 9543
Query: 793 GDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVP-----PPPPYLASYPG--FPENG 845
A PAE + +K + + P +P PPP + P PE
Sbjct: 9544 SKRVEAEPAE----------VTERQEKKIVLK-PKIPAKIEEPPPAKVPEAPKKIVPEKK 9592
Query: 846 APGP-------PISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEA 898
P P P + P EEP +P+P +V K++ P P K E Q+T E
Sbjct: 9593 VPAPVPKKEKVPPPKVP-EEP-KKPVPEKKVPPKVIKMEEPLPAK--VTERHMQITQEE- 9647
Query: 899 GRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPP 958
K V + + PP R P +R +P E+ + P ++ PP
Sbjct: 9648 --KVLVAV-TKKEAPPKAR-----------VPEEPKRAVPEEK----VLKLKPKREEEPP 9689
Query: 959 TKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE 996
KV E + +++ + + PK +P I + + KE
Sbjct: 9690 AKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKE 9727
Score = 52.8 bits (125), Expect = 4e-06
Identities = 127/573 (22%), Positives = 187/573 (32%), Gaps = 120/573 (20%)
Query: 500 PDKRLKAEPAAPPAAPSTPAPP---PAVPKELPAPPA--PPP-----------------A 537
PD R+ A P PP P +P LP P PPP
Sbjct: 8938 PDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVV 8997
Query: 538 SAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSF----------EAS 587
+ P T EE + PP +T P A AP ++ + EA
Sbjct: 8998 AKPKEMTPREEIVKKPPPPTTLIP--AKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAV 9055
Query: 588 PVEPQ---------LPSKEGPEPPEEVPPPTTP-------------PVPKVEPKGDGIGP 625
+ Q + S E P EV P T P KVE K +
Sbjct: 9056 YEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEE 9115
Query: 626 TRQPPSQGLGYPKYQKSLPP---RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPP 682
+ +G Y + ++ ++ QE+ + Q Q+ +++ + P
Sbjct: 9116 WEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVP--------- 9166
Query: 683 QPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP-- 740
VP +APPPP P M + + P V +++ +P
Sbjct: 9167 -----AKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT 9221
Query: 741 ------LDFYPPGVHPSGLV-PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
++ P VH +V E+ + E P + +E T + K+
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVT---EEKI---- 9274
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
V + EP P L +K E PVP P P PE P +
Sbjct: 9275 HVAISKRVEPPPKVPEL------PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK 9328
Query: 854 FPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGP 913
P+ P P PP EV PKK P+E+ + P A +K A P
Sbjct: 9329 KPVPVPKKEPAA-PPKVPEV-------PKKPVPEEK---IPVPVAKKKEA---------P 9368
Query: 914 PP--PRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQ 971
P P + T + R PP P++ P ++ P P K EE+PP P +
Sbjct: 9369 PAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPP--K 9426
Query: 972 GDETPKPPKPDPLKITKGKLGGPKETPPNGNLS 1004
PK P P+ K+ K PP +S
Sbjct: 9427 VPALPKKPVPEE-KVAVPVPVAKKAPPPRAEVS 9458
Score = 50.1 bits (118), Expect = 2e-05
Identities = 99/494 (20%), Positives = 165/494 (33%), Gaps = 78/494 (15%)
Query: 545 EPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEE 604
E + PA+ P ++ P P V P + ++ + + V P++ K P+ P
Sbjct: 9162 ERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKV-PEVSKKIVPQKPSR 9220
Query: 605 VPPPTTP---PVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQ 661
P VP V K I + + + + + + Q++++ +++
Sbjct: 9221 TPVQEEVIEVKVPAVHTKKMVISEEK------MFFASHTEEEVSVTVPEVQKEIVTEEKI 9274
Query: 662 HQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQ-APPPPPKALYPGALGRPPPMPPMNFD 720
H + P P P P P + VP P+ PP PK P P+
Sbjct: 9275 HVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVP 9334
Query: 721 PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
+ PP V P + + P + P V P + ++ RE
Sbjct: 9335 KKEPAAPPKV-PEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREE 9393
Query: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPP--PYLASY 838
PP P++ ++ E+ K + + VPPPP P L
Sbjct: 9394 SPPPAVPEIP--------------------KKKVPEERKPVPRKEEEVPPPPKVPALPKK 9433
Query: 839 PGFPENGAPGPPIS-------------------RFPLEEPGPRPLP-------------- 865
P E A P++ RF EE +P
Sbjct: 9434 PVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEE 9493
Query: 866 -WPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVG-------SGGQGPPPPR 917
W +E + ++E +EE A++T E +P V S P
Sbjct: 9494 EWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAE 9553
Query: 918 RESRTETR--WGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPT-KVEELPPKPLEQGDE 974
R E + P+ + PP + P++ P KK P P K E++PP + + +
Sbjct: 9554 VTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPK 9613
Query: 975 TPKPPKPDPLKITK 988
P P K P K+ K
Sbjct: 9614 KPVPEKKVPPKVIK 9627
Score = 48.5 bits (114), Expect = 7e-05
Identities = 82/367 (22%), Positives = 128/367 (34%), Gaps = 44/367 (11%)
Query: 371 PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGP-PAPKPPLPPPHRGPAGNWGPPGDY 429
PE K + P PK + PE P P K P+P P + PA
Sbjct: 9289 PELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAA-------- 9340
Query: 430 PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACA-- 487
P + K P PE++ ++K++ V++ E+ Q E A
Sbjct: 9341 PPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVP 9400
Query: 488 --EKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETE 545
K K +E+ P K + P PP P+ P P VP+E A P P AP P E
Sbjct: 9401 EIPKKKVPEERKPVPRKEEEVPP--PPKVPALPKKP--VPEEKVAVPVPVAKKAPPPRAE 9456
Query: 546 PEEPAQAPPAQSTPTPGVA-AAPTLVS-GGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE 603
+ + ++ A P V S+ S+ + E E
Sbjct: 9457 VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREE 9516
Query: 604 EVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
E T EP+ + S+ + + +RQ+++ +LK + +
Sbjct: 9517 EEEAEVTEYEVMEEPEEYVVEEKLHIISK-----RVEAEPAEVTERQEKKIVLKPKIPAK 9571
Query: 664 WQQHQQGSAPPTPVPPSPPQPVTLGAVPAP-----QAPPP----------PPKALYPGAL 708
++ PP VP +P + V VPAP + PPP P K + P +
Sbjct: 9572 IEE-----PPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVI 9626
Query: 709 GRPPPMP 715
P+P
Sbjct: 9627 KMEEPLP 9633
Score = 43.1 bits (100), Expect = 0.003
Identities = 152/793 (19%), Positives = 238/793 (30%), Gaps = 187/793 (23%)
Query: 863 PLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRT 922
P P S+++ + PP K P KE A++ PE +K V + P PR
Sbjct: 10439 PPKGPEISEKIIPPKKPPTKVVPRKEPPAKV--PEVPKKIV--VEEKVRVPEEPR----- 10489
Query: 923 ETRWGPRPGSSRRGIPPEEPGA--PPRRAGPIKKPP-PPTKVEELPPKPLEQGDETPKPP 979
+PP + PP+ P KK P PP K E PP PK P
Sbjct: 10490 --------------VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPP---------PKVP 10526
Query: 980 KPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFR 1039
+ + + K+ P P + P + + E+ P + +
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP--------- 10577
Query: 1040 GTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPK 1099
P P AP+ E +P+
Sbjct: 10578 --------------------------------PPEVPEAPK--------------EVVPE 10591
Query: 1100 RRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPP-PGAPPSPAPARFTARGG 1158
++ E + + KE K+ VP+ PP P PP+ P
Sbjct: 10592 KKVPAAPPKKPEVTPVKVPEAPKEVVPEKK-----VPVPPPKKPEVPPTKVPEVPKVAVP 10646
Query: 1159 RVFTPRGVPSRRGRGGGRPPPQVCPG------WSPPAKSLA---PKKPPTGPLPPSKEPL 1209
P +P + PPP+V PPA+ + P PP +PP K+P+
Sbjct: 10647 EKKVPEAIPPKPES----PPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPP-KKPV 10701
Query: 1210 KEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAAR 1269
EK P ++ V E + + + P + + +E +
Sbjct: 10702 PEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKK 10761
Query: 1270 GSEGKPSLTLPASAPG--PEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASES 1327
+ K PA P + L P P RA + P++ + + A EE E
Sbjct: 10762 VAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821
Query: 1328 SDFTSERRGDKEAPPPVL------LTPK----AVGTPGGGGGGAVPGISAMSRGDLSQR- 1376
+ E PPP + + P+ + P + + L R
Sbjct: 10822 KPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRP 10881
Query: 1377 --------AKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRG 1428
+D+ ++ F + ++ +P K + PGG +
Sbjct: 10882 PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKV------PGGEKKVRKL 10935
Query: 1429 DKRSWPSPKN--------RSRPPEERP------------PGLPLPPPPPSSSAVFRLDQV 1468
P PK R RP EE P P +P PPPP V
Sbjct: 10936 LPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV------ 10989
Query: 1469 IHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLS 1528
+ ++ R+ + P P KP +P P P+P + +
Sbjct: 10990 ----------EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT------IK 11033
Query: 1529 SDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSS------ 1582
P EP P+ V P PK P+ P + P P +
Sbjct: 11034 PPPVEPEPTPIAAPV-TVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLR 11092
Query: 1583 -GFLGSKPEGPGP 1594
G G KP P
Sbjct: 11093 PGSGGEKPPDEAP 11105
Score = 42.7 bits (99), Expect = 0.004
Identities = 65/293 (22%), Positives = 102/293 (34%), Gaps = 47/293 (16%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSA---VFRLDQVIHSNPAGIQQALAQLSSRQGSV 1490
P P+ P+ +P P PP PP +F+L + Q ++ +
Sbjct: 10866 PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT--PL 10923
Query: 1491 TAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDS 1550
PGG + + LP+ R P E + S L P EEP + + + +
Sbjct: 10924 KVPGGEKKVRKLLPE-------RKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPA 10976
Query: 1551 AGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHI 1610
P PPK E +E +P P + KP P P E + +
Sbjct: 10977 VPEPP-PPKPVEEVEVPTVTKRERKIPEPTKVPEI--KPAIPLPAPEPKPKPEAEV---- 11029
Query: 1611 WNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRS 1670
K+ +P +EP P++ + V + G + P + +
Sbjct: 11030 ----------KTIKPPPVEPEPTPIA------------APVTVPVVGKKAEAKAPKEEAA 11067
Query: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELP 1723
P G +KG P K P SP+ A + PGS + P AP K +P
Sbjct: 11068 KPKGPIKGV---PKKTP---SPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVP 11114
Score = 42.4 bits (98), Expect = 0.005
Identities = 45/195 (23%), Positives = 67/195 (34%), Gaps = 28/195 (14%)
Query: 380 SPNSEPPTPKTAWAETSRPPETEP-------GPPAPKPPLPPPHRGPAGNWGPPGDYPDR 432
S EPP E P E P PPAPK P P P P +
Sbjct: 9279 SKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEP 9338
Query: 433 GGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKR 492
PP P P K+ E + V A+++ + + ++ EK+
Sbjct: 9339 AAPPKVPEVP-----------KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITI 9387
Query: 493 LDEKFGAPD--------KRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAP-PPASAPTPE 543
+ ++ +P K++ E P PPP VP LP P P + P P
Sbjct: 9388 VTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVP-ALPKKPVPEEKVAVPVPV 9446
Query: 544 TEPEEPAQAPPAQST 558
+ P +A ++ T
Sbjct: 9447 AKKAPPPRAEVSKKT 9461
Score = 41.6 bits (96), Expect = 0.009
Identities = 108/506 (21%), Positives = 181/506 (35%), Gaps = 75/506 (14%)
Query: 1684 PKRPGGSSPLNAVPCEGPPGSE-PPRRPPPAPHDG-DRKELPREQPLPPG--PIGTERSQ 1739
P+ P + P VP PP E PP P AP + K++P P P P+ +
Sbjct: 10554 PEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP 10613
Query: 1740 RTDRGTEPGPIRPSHRPG-PPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRD 1798
+ + P+ P +P PP + K + V +++ + E P
Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPES--------PPPEV 10665
Query: 1799 WELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLH 1858
+E P A EP ++ ++ PEP++ Q P P + A +L
Sbjct: 10666 FEE-PEEVALEEPPAEVVEE----PEPAAPPQVTVPPK---KPVPEKKAPAVVAKKPELP 10717
Query: 1859 PNSGGFRPGTPS-LHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPA 1917
P P P + P + PL +P P P A + + + + + + ++P
Sbjct: 10718 PVKV---PEVPKEVVPEKKVPLVVPKKPEAPPAKVP--EVPKEVVPEKKVAVPKKPEVPP 10772
Query: 1918 GGVLYPP--PSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAP 1975
V P P PA P+P+ R + P P + Y P + + AP
Sbjct: 10773 AKVPEVPKKPVLEEKPAV---PVPE------RAESPPP-EVYEEPEEIAPEEEI----AP 10818
Query: 1976 AQQMLLPMVDSQLPVVNFGSLPPAP--------------PPAPPPLSLLPVGPALQPPSL 2021
++ +P+ + + P V ++P P P APPP P ++ P L
Sbjct: 10819 EEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPE-KVIEKPKL 10877
Query: 2022 AVRPPPAPATRVLPSPARPFPASLGRAELHP---VELKPFQDYQKLSSNLGGPGSSR--- 2075
RPPP P P + + + P V KP + + L PG +
Sbjct: 10878 KPRPPPPPPA----PPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVR 10933
Query: 2076 -----TPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGP 2130
P + L S L+ P ++++ ++ + P+ PKP E
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPP--PKPVEEVEV 10991
Query: 2131 PPREGPSRRAEEPGSRGDKEPGLPPP 2156
P R+ EP + +P +P P
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLP 11017
Score = 34.7 bits (78), Expect = 1.0
Identities = 66/340 (19%), Positives = 118/340 (34%), Gaps = 62/340 (18%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
P PK PP + P +P P P V + + + PA + + +L + T
Sbjct: 10020 PVPKKVEAPPA-KVPEVPKKPVPEKKVPV-PAPKKVEAPPAKVPEVPKKLIPEEKKPTP- 10076
Query: 1494 GGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSD----------------PHFEEPG 1537
+P+ + P P+ P + EP V L + P EE
Sbjct: 10077 ---------VPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVL 10127
Query: 1538 PMVRGVGGTPRDSAGV---SPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPE---- 1590
P V P + + PP+ E PP + + +EE P KP+
Sbjct: 10128 PEEEEV--LPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV-LPEVKPKVPVP 10184
Query: 1591 GPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSD 1650
P P+ + + T + + P + ++ P +E L E+V E+++
Sbjct: 10185 APVPEIKKKVTEKKVVIP---KKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEP 10241
Query: 1651 SGVDLSGDSQVSSGPCS----------------QRSSPDGG--LKGAAEGPPKRPGGSSP 1692
+S + ++ P S +++ P+ + E PP + P
Sbjct: 10242 EEEPIS-EEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP 10300
Query: 1693 LNAVPCEGPPGSEPPRRPPPAPHDGDRKE--LPREQPLPP 1730
VP PP + P P K+ +P+++ +PP
Sbjct: 10301 EEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPP 10340
Score = 33.9 bits (76), Expect = 1.8
Identities = 39/167 (23%), Positives = 56/167 (33%), Gaps = 36/167 (21%)
Query: 1443 PEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPG 1502
P + P LP P P + V +V P + + + V P P P
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPK 9343
Query: 1503 LPQAPQGPSPR-------------PPTRYEPQRVNSGLSSDPHF-------EEPGPMVRG 1542
+P+ P+ P P PP + V G+ ++ E P P V
Sbjct: 9344 VPEVPKKPVPEEKIPVPVAKKKEAPPAKVP--EVQKGVVTEEKITIVTQREESPPPAV-- 9399
Query: 1543 VGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKP 1589
P PK++ RKP +EE +PPP L KP
Sbjct: 9400 ------------PEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKP 9434
Score = 32.7 bits (73), Expect = 3.9
Identities = 124/652 (19%), Positives = 203/652 (31%), Gaps = 139/652 (21%)
Query: 1442 PPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKP 1501
PP+E P +P PP + P + +A ++ + V P P KP
Sbjct: 10500 PPKEVVPEKKVPVPPAKKP---------EAPPPKVPEAPKEVVPEK-KVPVP---PPKKP 10546
Query: 1502 GLP--QAPQGPSPRPPTRYEPQRVNSGLSSDPHF--EEPGPMV--RGVGGTPRDSAGVSP 1555
+P + P+ P P + P+ + S P E P +V + V P V+P
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 1556 F------------------PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAE 1597
PPK+ E PP K + + ++P + KPE P P+
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF 10666
Query: 1598 SRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSG 1657
P P+ + EP +P + +
Sbjct: 10667 EEPEEVALEEP----------------PAEVVEEPEPAAPPQVTVPPKK----------- 10699
Query: 1658 DSQVSSGPCSQRSSPDGGLKGAAEGP---PKRPGGSSPLNAVPCEGPPGSE-PPRRPPPA 1713
P ++ +P K P P+ P P VP P E PP + P
Sbjct: 10700 -------PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752
Query: 1714 PHD---GDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSD 1770
P + + +P++ +PP + E ++ +P P PP + ++
Sbjct: 10753 PKEVVPEKKVAVPKKPEVPPAKV-PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE-- 10809
Query: 1771 LRLVVGDSLKAEKELTASVTEAIPVSRDWE-LLPSAAASAEPQSKNLDSGHCVPEPSSSG 1829
+ E+E+ + +PV+ + E +P A EP+ +PE
Sbjct: 10810 --------IAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK-------IIPE----- 10849
Query: 1830 QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPS 1889
+ P + A P ++ P L P PP PAPP
Sbjct: 10850 -KKVPVIKKPEAPPPKEPEPEKVIEK-------------PKLKPRPP-----PPPPAPPK 10890
Query: 1890 A-------LLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTS 1942
L + K + EL L G L P P P +
Sbjct: 10891 EDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLL--PERKPEPKEEVV 10948
Query: 1943 LLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPP 2002
L V + P + ++P P P+ + ++P V
Sbjct: 10949 LKSVLRKRPEEEE---PKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVT-----KRERK 11000
Query: 2003 APPPLSLLPVGPALQPPSLAVRP-PPAPATRVLPSPARPFPASLGRAELHPV 2053
P P + + PA+ P+ +P P A + P P P P + PV
Sbjct: 11001 IPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV 11052
Score = 32.0 bits (71), Expect = 6.7
Identities = 37/138 (26%), Positives = 49/138 (35%), Gaps = 23/138 (16%)
Query: 1492 APGGHPRHK--PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRD 1549
A G HK P +P P+ SP PP+ ++ S P P P+ TP
Sbjct: 244 AAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSP 303
Query: 1550 SAGVSP-----FPPKRRERPPRKPELLQEESL-------PPPHSSGFLGSKPEGPGPQAE 1597
VSP P R R P Q ++ PP G++ S E AE
Sbjct: 304 VRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSE-----AE 358
Query: 1598 SRD----TGTEALTPHIW 1611
R+ T T+ T W
Sbjct: 359 MRETTLTTSTQIRTEERW 376
Score = 32.0 bits (71), Expect = 6.7
Identities = 67/293 (22%), Positives = 98/293 (33%), Gaps = 60/293 (20%)
Query: 1436 PKNRSRPPE--ERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
PK S PPE E P + L PP + V PA Q AP
Sbjct: 10656 PKPESPPPEVFEEPEEVALEEPPA--------EVVEEPEPAAPPQVTVPPKKPVPEKKAP 10707
Query: 1494 GGHPRHKPGLP--QAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSA 1551
+ KP LP + P+ P P + P V + P V P++
Sbjct: 10708 AVVAK-KPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPP---------AKVPEVPKEVV 10757
Query: 1552 GVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIW 1611
P+++ P+KPE+ +P L KP P P+ E+ P ++
Sbjct: 10758 ------PEKKVAVPKKPEV-PPAKVPEVPKKPVLEEKPAVPVPER------AESPPPEVY 10804
Query: 1612 NRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSS 1671
EP E ++P E++A E + V ++ + + P +
Sbjct: 10805 E----------------EP--EEIAPEEEIAPEE----EKPVPVAEEEEPEVPPPAVPEE 10842
Query: 1672 PDGGLKGAAEGPPKRPGGSSPLNAVP---CEGPPGSEPPRRPPPAPHDGDRKE 1721
P + K+P P P E P P PPPAP D KE
Sbjct: 10843 PKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKE 10895
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 119 bits (299), Expect = 2e-26
Identities = 182/787 (23%), Positives = 259/787 (32%), Gaps = 130/787 (16%)
Query: 336 TEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAET 395
T+K+ S+E S E E S S+S + K ++ N E K +
Sbjct: 104 TKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE--LQKKLKVKD 161
Query: 396 SRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDY----PDRGGP---------------- 435
++ T+ P PKPP+ AG+ GD+ PD
Sbjct: 162 NKKNRTKK-KPTPKPPVVDE----AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 216
Query: 436 ----PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLK 491
P PP + E K+++ E ++ + + + + EK
Sbjct: 217 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 276
Query: 492 RLDEKFGAPDKRLKAEPAAP-------PAAPSTPAPPPAVPKELPA-------------- 530
D AP ++ A+P PA + P P PKE PA
Sbjct: 277 AKDL---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-PASTTPKEPTPTTIKS 332
Query: 531 ----PPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586
P P P + + T P+EPA + PT APT T++ S+ +
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392
Query: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646
P P P K P P+E P PTTP P + T++P P K P
Sbjct: 393 EPA-PTTPKKPAPTTPKE-PAPTTPKEPTPTTPKEPAPTTKEPA------PTTPKEPAPT 444
Query: 647 FQRQQQEQLLKQQQQHQWQQHQQGSA-PPTPVPPSPPQPVTLGAVPAPQAPPPP------ 699
++ K+ ++ + P+P P P P T + P P P
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Query: 700 ---PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV-HPSGLVP 755
PK P P P P P P P+ P + P P+ P
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564
Query: 756 RERSDSGGSSSEP-----FDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLT--- 807
+E + + + P P L T P P ++ TP EP P T
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPAPTTPEELAPTTPEEPTPTTPEE 622
Query: 808 ---SPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFP--LEEPGPR 862
+ + AA K TP P P P P+ AP P P L+EP P
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP- 681
Query: 863 PLPWPPGSDEVAKIQTPPPKK---EPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRE 919
P P E+A T P + P T + T P ++PA P P+
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGT 740
Query: 920 SRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIK----KPPPPTKVEELPPKPLEQGDET 975
+ T T P P + ++ P E AP GP KP P T E P P E T
Sbjct: 741 APT-TLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797
Query: 976 PKPPKP--------------------DPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSY 1015
PK P P +P I K P E+ P + P P+ +
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSAEPTPKALENSPK 853
Query: 1016 ERVGPTS 1022
E PT+
Sbjct: 854 EPGVPTT 860
Score = 87.4 bits (215), Expect = 1e-16
Identities = 181/896 (20%), Positives = 270/896 (30%), Gaps = 155/896 (17%)
Query: 508 PAAPPAAPSTPAPPPA---VPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
P +PP++ P P A + P PP E EE + +
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128
Query: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG 624
++ + S +S S ++ +L K+ + + P PPV V+ G G+
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPV--VDEAGSGLD 186
Query: 625 ----PTRQPPSQGLGYPKY--------------QKSLPPRFQRQQQEQLLKQQQQHQWQQ 666
P + + K + SLPP ++ L ++ +
Sbjct: 187 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 667 HQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMI 726
+ T + + T A K L P + P P +
Sbjct: 247 ETTTTNKQTS---TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK---- 299
Query: 727 PPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRH-APAMLRERGTPPV 785
P L + P P P+ P+E + + S+ + AP + T P
Sbjct: 300 ----GPALTTPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353
Query: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845
+P + TP EP P T+ P P S P P+
Sbjct: 354 EPAPTTTKEPAPTTPKEPAPTTTK-------------------EPAPTTTKSAPTTPKEP 394
Query: 846 APGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG 905
AP P + P P P P + P P + P T + P A +KPA
Sbjct: 395 APTTP--KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-- 450
Query: 906 VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--PEEPGAPPRRAGPIK-KPPPPTKVE 962
P +E T P P +++ P P+EP ++ P K P PT +
Sbjct: 451 --------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 963 ELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRD---YSYERVG 1019
P P E T K P P PKE P PAP ++ + +
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTT----------PKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP 1079
PT+ + P P P
Sbjct: 553 PTTTK---------------------------------------------KPAPTTPKEP 567
Query: 1080 RGRTASETRSEGSEY--EEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPL 1137
T ET + P++ E + T +LAP+ E PTP T + P
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP---TTPEEPA 624
Query: 1138 APPP----PGAPPSPAPARFTARGGRVFTPRG-VPSRRGRGGGRPPPQVCPGWSPPAKSL 1192
P P P PAP T + TP+ P+ P P
Sbjct: 625 PTTPKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 1193 APKKPPTGPLPPS--KEPLKEKLI-PGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
PKKP L P+ KEP P P +P + E G A
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 1250 QQDKPPRFRRLKQE--RENAARGSEGKPSLTLPASAPG---------PEEALTTVTVAPA 1298
K P K+ +E A ++G S T AP P+E T PA
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 802
Query: 1299 PRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354
P P S ++ +E T +S D ++ + P + +PK G P
Sbjct: 803 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858
Score = 75.5 bits (184), Expect = 5e-13
Identities = 146/646 (22%), Positives = 205/646 (31%), Gaps = 114/646 (17%)
Query: 383 SEPPTPKTAWAETSRPPET----EPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPC- 437
S P TPK T++ P EP P PK P P + PA P P P
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPAPTTTKKPAP 561
Query: 438 ---KPPAPEDEDEAWRQRRKQSSSEI------SLAVERARRRREEEERRMQEERRAACAE 488
K PAP E K+ + + + A EE EE E
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621
Query: 489 KLKRLDEKFGAPDKRLKAEPAAPPA-APSTPAPP-PAVPKELPAPPAPPPASAPTPETEP 546
+ K AP+ + P P AP+TP P P PKE P P +APT EP
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE--TAPTTPKGTAPTTLKEP 679
Query: 547 EEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVP 606
PA P PT + +T G+ +P EP P P+E P
Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP------APTTPKE-P 732
Query: 607 PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQ 666
PTTP G PT LK+
Sbjct: 733 APTTP---------KGTAPT----------------------------TLKE-------- 747
Query: 667 HQQGSAPPTPVPPSPPQ---PVTLGAVPAPQAPPPP--PKALYPGALGRPPPMPPMNFDP 721
AP TP P+P + T G P P PK P P P P P
Sbjct: 748 ----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 722 RWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERG 781
PP + P P +H S P E + S+EP + +E G
Sbjct: 804 TTPETPPPTTSEV--STPTTTKEPTTIHKS---PDESTPE--LSAEPTPKALENSPKEPG 856
Query: 782 TPPVDPKLAWVGDVFTATPAEPRP-LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
P T TPA +P +T+ + E D +R+ TP P +
Sbjct: 857 VPT------------TKTPAATKPEMTTTAKDKTTERD--LRT-TPETTTAAPKMTKETA 901
Query: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKE---ETAQLTGPE 897
I+ + P K T PK K+ T + PE
Sbjct: 902 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 961
Query: 898 AGRKPARGVGSGGQGPPPPRRESR-----TETRWGPRPGSSRRGIPPEEPGAPPRRAGPI 952
KP + P P++ ++ T T+ +P + R P+ P + +
Sbjct: 962 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK---KPKTMPRVRKPKTTPTPRKMTSTM 1018
Query: 953 KKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETP 998
+ P +++ E + + ++TP + ++ G ETP
Sbjct: 1019 PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1064
Score = 49.3 bits (116), Expect = 4e-05
Identities = 133/674 (19%), Positives = 206/674 (30%), Gaps = 123/674 (18%)
Query: 1083 TASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDK--EAPTPKEGTLTQVP-LAP 1139
T +T ++G E K + +++ +T DLAP+ K PTPK T T+ P L
Sbjct: 251 TNKQTSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 305
Query: 1140 PPPGAPPSPA-PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP 1198
P P +P PA T + T + P+ P + P K P
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAP--------TTTKSAP 349
Query: 1199 TGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFR 1258
T P P+ KE P P +P + P + KP
Sbjct: 350 TTPKEPAPTTTKE---PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--- 403
Query: 1259 RLKQERENAARGSEGKPSLTLPAS-APGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA 1317
+ A + +P+ T P AP +E T PAP +P
Sbjct: 404 --PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT--------- 452
Query: 1318 NEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRA 1377
T E + T + P TPK P + + + A
Sbjct: 453 -----TPKEPAPTTPKEPAPTTTKEPSPTTPKE----------PAPTTTKSAPTTTKEPA 497
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPK 1437
+K + ++ + + P P T P K P+
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAP---------------------TTP----KEPAPTTP 532
Query: 1438 NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQ-QALAQLSSRQGSVTAPGGH 1496
+ P + P P P P+ + + PA + A + ++ + T P
Sbjct: 533 KKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--- 588
Query: 1497 PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMV--RGVGGTPRDSAGVS 1554
+ P P+ P+P P P + P EEP P TP++ A +
Sbjct: 589 ---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--EEPAPTTPKAAAPNTPKEPAPTT 643
Query: 1555 PFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRL 1614
P P P++P + P G + + P P + E L P
Sbjct: 644 PKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAP---TTT 697
Query: 1615 HTATSRKSYRPSSMEP-WMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPD 1673
TS +P+ P P +P E T + P + + +
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA---------------PTTPKGTAP 742
Query: 1674 GGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPI 1733
LK A PK+P L +GP + + P P KE P P P
Sbjct: 743 TTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTPKEPAPT 796
Query: 1734 GTERSQRTDRGTEP 1747
++ T T P
Sbjct: 797 TPKKPAPTTPETPP 810
Score = 38.9 bits (89), Expect = 0.055
Identities = 69/355 (19%), Positives = 111/355 (31%), Gaps = 46/355 (12%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
P+P P P P P+ + + PA + ++ + T P
Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------PTTPKEPTPTTP 423
Query: 1494 GGH-PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
P K P P+ P+P P + P + P P TP++ A
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483
Query: 1553 VS----------PFPPKRRERP--PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRD 1600
+ P P + P P++P + P + P+ P P
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543
Query: 1601 TGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGDS 1659
T P T++K + EP P +P E T + + + L+ +
Sbjct: 544 APTTPKEP------APTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTT 595
Query: 1660 QVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDR 1719
P + + P+ P ++P A P P+ P P
Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 648
Query: 1720 KELPREQPLPPGPIGTERSQRTDRGT------EPGPIRPSHRPGPPVQFGTSDKD 1768
P+E P P P E + T +GT EP P P +P P T+ K+
Sbjct: 649 PTTPKE-PAPTTP--KETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKE 699
Score = 38.5 bits (88), Expect = 0.072
Identities = 87/448 (19%), Positives = 144/448 (32%), Gaps = 44/448 (9%)
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRG----TEPGPIRPSHRPGPPVQFGTSDKDSDLRL 1773
++K +++P P P+ E D G T P H T+ K + R
Sbjct: 162 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 221
Query: 1774 VVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLY 1833
+ + KE + +V + V + S + + K + +S + L
Sbjct: 222 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 281
Query: 1834 P--EVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSAL 1891
P +V + + G A+ + P P TP +P P P+ +
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPT-----PTTPK------EPASTTPKEPTPTTI 330
Query: 1892 LSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLP 1951
S + +T A K PA P +P P P T+ P
Sbjct: 331 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTT------KEP 379
Query: 1952 SPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLP 2011
+P+ S P P + P PA P + P P P P + P
Sbjct: 380 APTTTKSAPTTPKEPAPTTPK-KPA-----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 433
Query: 2012 VGPALQPPSLAVRPPPAPATRVLPSPARP-FPASLGRAELHPVELKPFQDYQKLSSNLGG 2070
+ P+ PAP T P+P P PA E P K ++
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSA 489
Query: 2071 PGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIP-KPWERTG 2129
P +++ P + S + + +P+T T ++ +P + P P E
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAP 545
Query: 2130 PPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
P+E ++P KEP P+
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPK 573
Score = 35.8 bits (81), Expect = 0.47
Identities = 127/591 (21%), Positives = 181/591 (30%), Gaps = 71/591 (12%)
Query: 80 PKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGV 139
PK+ A K+ A T P E P + P+ PK P AP T P+
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTT-PKEPAPTTTKE-PSPTTPKEP--APTTTKSAPTTT 493
Query: 140 KSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSL 199
K A + T A S ++ E PT K + + P
Sbjct: 494 KEPAPTT-TKSAPTTPKEPSPTTTK---EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549
Query: 200 RPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL 259
P +TT + P E K P+ L P+ P + P P P L
Sbjct: 550 EPAPTTT-KKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEEL 607
Query: 260 PFPPPYGPQGPYRYPTPDGPS-RFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQL 318
P P+ P TP+ P+ P+ A P P P+ KE +
Sbjct: 608 A---PTTPEEPTP-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663
Query: 319 DQENDDGWAGAH-EEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQS-----ASGEERPPE 372
G A +E T K + +E + +E D + + P E
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723
Query: 373 ADGKKGNSPNSEPPTPK-TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWG--PPGDY 429
P P TPK TA P T P PAPK P +GP P
Sbjct: 724 PAPTTPKEP--APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781
Query: 430 PDRGGPPCK----PPAPEDEDEAWRQRRKQSSSEISL--AVERARRRREEEERRMQEERR 483
P P P P+ + ++SE+S + + + E
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 484 AACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPAS----- 538
+ L+ ++ G P + PAA +T A ++L P A+
Sbjct: 842 EPTPKALENSPKEPGVPTTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 898
Query: 539 --APTPETEPEEPAQAPPAQSTPTPGVAAAP---------TLVSGGGSTSST-------- 579
A T E E A Q T T P TL +T T
Sbjct: 899 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 958
Query: 580 ----------SSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV--PKVEP 618
+ + +A+ +PQ P+K +P P T P V PK P
Sbjct: 959 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1009
Score = 33.5 bits (75), Expect = 2.3
Identities = 39/204 (19%), Positives = 61/204 (29%), Gaps = 7/204 (3%)
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHT 1616
P + E + P L + P + P+ P P T +
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGL 1676
T ++ ++ EP P +P E T + + + + P + +
Sbjct: 350 TTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 1677 KGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE----QPLPPGP 1732
K A PK P ++P P P P+ P P P+E P P P
Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 467
Query: 1733 IGTERSQRTDRGTEPGPIRPSHRP 1756
T+ T EP P P
Sbjct: 468 TTTKEPSPT-TPKEPAPTTTKSAP 490
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 119 bits (299), Expect = 2e-26
Identities = 182/787 (23%), Positives = 259/787 (32%), Gaps = 130/787 (16%)
Query: 336 TEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAET 395
T+K+ S+E S E E S S+S + K ++ N E K +
Sbjct: 145 TKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRE--LQKKLKVKD 202
Query: 396 SRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDY----PDRGGP---------------- 435
++ T+ P PKPP+ AG+ GD+ PD
Sbjct: 203 NKKNRTKK-KPTPKPPVVDE----AGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP 257
Query: 436 ----PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLK 491
P PP + E K+++ E ++ + + + + EK
Sbjct: 258 INPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS 317
Query: 492 RLDEKFGAPDKRLKAEPAAP-------PAAPSTPAPPPAVPKELPA-------------- 530
D AP ++ A+P PA + P P PKE PA
Sbjct: 318 AKDL---APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE-PASTTPKEPTPTTIKS 373
Query: 531 ----PPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586
P P P + + T P+EPA + PT APT T++ S+ +
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433
Query: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646
P P P K P P+E P PTTP P + T++P P K P
Sbjct: 434 EPA-PTTPKKPAPTTPKE-PAPTTPKEPTPTTPKEPAPTTKEPA------PTTPKEPAPT 485
Query: 647 FQRQQQEQLLKQQQQHQWQQHQQGSA-PPTPVPPSPPQPVTLGAVPAPQAPPPP------ 699
++ K+ ++ + P+P P P P T + P P P
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
Query: 700 ---PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV-HPSGLVP 755
PK P P P P P P P+ P + P P+ P
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 605
Query: 756 RERSDSGGSSSEP-----FDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLT--- 807
+E + + + P P L T P P ++ TP EP P T
Sbjct: 606 KEPAPTTPKETAPTTPKKLTPTTPEKLAP--TTPEKPAPTTPEELAPTTPEEPTPTTPEE 663
Query: 808 ---SPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFP--LEEPGPR 862
+ + AA K TP P P P P+ AP P P L+EP P
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP- 722
Query: 863 PLPWPPGSDEVAKIQTPPPKK---EPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRE 919
P P E+A T P + P T + T P ++PA P P+
Sbjct: 723 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-EPAPTTPKGT 781
Query: 920 SRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIK----KPPPPTKVEELPPKPLEQGDET 975
+ T T P P + ++ P E AP GP KP P T E P P E T
Sbjct: 782 APT-TLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838
Query: 976 PKPPKP--------------------DPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSY 1015
PK P P +P I K P E+ P + P P+ +
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSAEPTPKALENSPK 894
Query: 1016 ERVGPTS 1022
E PT+
Sbjct: 895 EPGVPTT 901
Score = 87.4 bits (215), Expect = 1e-16
Identities = 181/896 (20%), Positives = 270/896 (30%), Gaps = 155/896 (17%)
Query: 508 PAAPPAAPSTPAPPPA---VPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVA 564
P +PP++ P P A + P PP E EE + +
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169
Query: 565 AAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIG 624
++ + S +S S ++ +L K+ + + P PPV V+ G G+
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPV--VDEAGSGLD 227
Query: 625 ----PTRQPPSQGLGYPKY--------------QKSLPPRFQRQQQEQLLKQQQQHQWQQ 666
P + + K + SLPP ++ L ++ +
Sbjct: 228 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 667 HQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMI 726
+ T + + T A K L P + P P +
Sbjct: 288 ETTTTNKQTS---TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK---- 340
Query: 727 PPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRH-APAMLRERGTPPV 785
P L + P P P+ P+E + + S+ + AP + T P
Sbjct: 341 ----GPALTTPKEPTPTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394
Query: 786 DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENG 845
+P + TP EP P T+ P P S P P+
Sbjct: 395 EPAPTTTKEPAPTTPKEPAPTTTK-------------------EPAPTTTKSAPTTPKEP 435
Query: 846 APGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG 905
AP P + P P P P + P P + P T + P A +KPA
Sbjct: 436 APTTP--KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA-- 491
Query: 906 VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--PEEPGAPPRRAGPIK-KPPPPTKVE 962
P +E T P P +++ P P+EP ++ P K P PT +
Sbjct: 492 --------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 963 ELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRD---YSYERVG 1019
P P E T K P P PKE P PAP ++ + +
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTT----------PKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 1020 PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP 1079
PT+ + P P P
Sbjct: 594 PTTTK---------------------------------------------KPAPTTPKEP 608
Query: 1080 RGRTASETRSEGSEY--EEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPL 1137
T ET + P++ E + T +LAP+ E PTP T + P
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP---TTPEEPA 665
Query: 1138 APPP----PGAPPSPAPARFTARGGRVFTPRG-VPSRRGRGGGRPPPQVCPGWSPPAKSL 1192
P P P PAP T + TP+ P+ P P
Sbjct: 666 PTTPKAAAPNTPKEPAPT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 1193 APKKPPTGPLPPS--KEPLKEKLI-PGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
PKKP L P+ KEP P P +P + E G A
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 1250 QQDKPPRFRRLKQE--RENAARGSEGKPSLTLPASAPG---------PEEALTTVTVAPA 1298
K P K+ +E A ++G S T AP P+E T PA
Sbjct: 784 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 843
Query: 1299 PRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354
P P S ++ +E T +S D ++ + P + +PK G P
Sbjct: 844 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899
Score = 75.5 bits (184), Expect = 5e-13
Identities = 146/646 (22%), Positives = 205/646 (31%), Gaps = 114/646 (17%)
Query: 383 SEPPTPKTAWAETSRPPET----EPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPC- 437
S P TPK T++ P EP P PK P P + PA P P P
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT-PKEPAPTTTKKPAP 602
Query: 438 ---KPPAPEDEDEAWRQRRKQSSSEI------SLAVERARRRREEEERRMQEERRAACAE 488
K PAP E K+ + + + A EE EE E
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662
Query: 489 KLKRLDEKFGAPDKRLKAEPAAPPA-APSTPAPP-PAVPKELPAPPAPPPASAPTPETEP 546
+ K AP+ + P P AP+TP P P PKE P P +APT EP
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE--TAPTTPKGTAPTTLKEP 720
Query: 547 EEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVP 606
PA P PT + +T G+ +P EP P P+E P
Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP------APTTPKE-P 773
Query: 607 PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQ 666
PTTP G PT LK+
Sbjct: 774 APTTP---------KGTAPT----------------------------TLKE-------- 788
Query: 667 HQQGSAPPTPVPPSPPQ---PVTLGAVPAPQAPPPP--PKALYPGALGRPPPMPPMNFDP 721
AP TP P+P + T G P P PK P P P P P
Sbjct: 789 ----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 722 RWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERG 781
PP + P P +H S P E + S+EP + +E G
Sbjct: 845 TTPETPPPTTSEV--STPTTTKEPTTIHKS---PDESTPE--LSAEPTPKALENSPKEPG 897
Query: 782 TPPVDPKLAWVGDVFTATPAEPRP-LTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
P T TPA +P +T+ + E D +R+ TP P +
Sbjct: 898 VPT------------TKTPAATKPEMTTTAKDKTTERD--LRT-TPETTTAAPKMTKETA 942
Query: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKE---ETAQLTGPE 897
I+ + P K T PK K+ T + PE
Sbjct: 943 TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE 1002
Query: 898 AGRKPARGVGSGGQGPPPPRRESR-----TETRWGPRPGSSRRGIPPEEPGAPPRRAGPI 952
KP + P P++ ++ T T+ +P + R P+ P + +
Sbjct: 1003 ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK---KPKTMPRVRKPKTTPTPRKMTSTM 1059
Query: 953 KKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETP 998
+ P +++ E + + ++TP + ++ G ETP
Sbjct: 1060 PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1105
Score = 49.3 bits (116), Expect = 4e-05
Identities = 133/674 (19%), Positives = 206/674 (30%), Gaps = 123/674 (18%)
Query: 1083 TASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDK--EAPTPKEGTLTQVP-LAP 1139
T +T ++G E K + +++ +T DLAP+ K PTPK T T+ P L
Sbjct: 292 TNKQTSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 346
Query: 1140 PPPGAPPSPA-PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP 1198
P P +P PA T + T + P+ P + P K P
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--------PKEPAP--------TTTKSAP 390
Query: 1199 TGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFR 1258
T P P+ KE P P +P + P + KP
Sbjct: 391 TTPKEPAPTTTKE---PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--- 444
Query: 1259 RLKQERENAARGSEGKPSLTLPAS-APGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQA 1317
+ A + +P+ T P AP +E T PAP +P
Sbjct: 445 --PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT--------- 493
Query: 1318 NEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRA 1377
T E + T + P TPK P + + + A
Sbjct: 494 -----TPKEPAPTTPKEPAPTTTKEPSPTTPKE----------PAPTTTKSAPTTTKEPA 538
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPK 1437
+K + ++ + + P P T P K P+
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAP---------------------TTP----KEPAPTTP 573
Query: 1438 NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQ-QALAQLSSRQGSVTAPGGH 1496
+ P + P P P P+ + + PA + A + ++ + T P
Sbjct: 574 KKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--- 629
Query: 1497 PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMV--RGVGGTPRDSAGVS 1554
+ P P+ P+P P P + P EEP P TP++ A +
Sbjct: 630 ---EKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--EEPAPTTPKAAAPNTPKEPAPTT 684
Query: 1555 PFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRL 1614
P P P++P + P G + + P P + E L P
Sbjct: 685 PKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE-LAP---TTT 738
Query: 1615 HTATSRKSYRPSSMEP-WMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPD 1673
TS +P+ P P +P E T + P + + +
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA---------------PTTPKGTAP 783
Query: 1674 GGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPI 1733
LK A PK+P L +GP + + P P KE P P P
Sbjct: 784 TTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSDKPAPTTP-----KETAPTTPKEPAPT 837
Query: 1734 GTERSQRTDRGTEP 1747
++ T T P
Sbjct: 838 TPKKPAPTTPETPP 851
Score = 38.9 bits (89), Expect = 0.055
Identities = 69/355 (19%), Positives = 111/355 (31%), Gaps = 46/355 (12%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
P+P P P P P+ + + PA + ++ + T P
Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------PTTPKEPTPTTP 464
Query: 1494 GGH-PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
P K P P+ P+P P + P + P P TP++ A
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524
Query: 1553 VS----------PFPPKRRERP--PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRD 1600
+ P P + P P++P + P + P+ P P
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584
Query: 1601 TGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGDS 1659
T P T++K + EP P +P E T + + + L+ +
Sbjct: 585 APTTPKEP------APTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTT 636
Query: 1660 QVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDR 1719
P + + P+ P ++P A P P+ P P
Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 689
Query: 1720 KELPREQPLPPGPIGTERSQRTDRGT------EPGPIRPSHRPGPPVQFGTSDKD 1768
P+E P P P E + T +GT EP P P +P P T+ K+
Sbjct: 690 PTTPKE-PAPTTP--KETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKE 740
Score = 38.5 bits (88), Expect = 0.072
Identities = 87/448 (19%), Positives = 144/448 (32%), Gaps = 44/448 (9%)
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRG----TEPGPIRPSHRPGPPVQFGTSDKDSDLRL 1773
++K +++P P P+ E D G T P H T+ K + R
Sbjct: 203 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 262
Query: 1774 VVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLY 1833
+ + KE + +V + V + S + + K + +S + L
Sbjct: 263 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 322
Query: 1834 P--EVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSAL 1891
P +V + + G A+ + P P TP +P P P+ +
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPT-----PTTPK------EPASTTPKEPTPTTI 371
Query: 1892 LSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLP 1951
S + +T A K PA P +P P P T+ P
Sbjct: 372 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTT------KEP 420
Query: 1952 SPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLP 2011
+P+ S P P + P PA P + P P P P + P
Sbjct: 421 APTTTKSAPTTPKEPAPTTPK-KPA-----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 474
Query: 2012 VGPALQPPSLAVRPPPAPATRVLPSPARP-FPASLGRAELHPVELKPFQDYQKLSSNLGG 2070
+ P+ PAP T P+P P PA E P K ++
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSA 530
Query: 2071 PGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIP-KPWERTG 2129
P +++ P + S + + +P+T T ++ +P + P P E
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAP 586
Query: 2130 PPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
P+E ++P KEP P+
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPK 614
Score = 35.8 bits (81), Expect = 0.47
Identities = 127/591 (21%), Positives = 181/591 (30%), Gaps = 71/591 (12%)
Query: 80 PKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGV 139
PK+ A K+ A T P E P + P+ PK P AP T P+
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTT-PKEPAPTTTKE-PSPTTPKEP--APTTTKSAPTTT 534
Query: 140 KSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSL 199
K A + T A S ++ E PT K + + P
Sbjct: 535 KEPAPTT-TKSAPTTPKEPSPTTTK---EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590
Query: 200 RPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYL 259
P +TT + P E K P+ L P+ P + P P P L
Sbjct: 591 EPAPTTT-KKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEEL 648
Query: 260 PFPPPYGPQGPYRYPTPDGPS-RFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQL 318
P P+ P TP+ P+ P+ A P P P+ KE +
Sbjct: 649 A---PTTPEEPTP-TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704
Query: 319 DQENDDGWAGAH-EEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQS-----ASGEERPPE 372
G A +E T K + +E + +E D + + P E
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764
Query: 373 ADGKKGNSPNSEPPTPK-TAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWG--PPGDY 429
P P TPK TA P T P PAPK P +GP P
Sbjct: 765 PAPTTPKEP--APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822
Query: 430 PDRGGPPCK----PPAPEDEDEAWRQRRKQSSSEISL--AVERARRRREEEERRMQEERR 483
P P P P+ + ++SE+S + + + E
Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 484 AACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPAS----- 538
+ L+ ++ G P + PAA +T A ++L P A+
Sbjct: 883 EPTPKALENSPKEPGVPTTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 939
Query: 539 --APTPETEPEEPAQAPPAQSTPTPGVAAAP---------TLVSGGGSTSST-------- 579
A T E E A Q T T P TL +T T
Sbjct: 940 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 999
Query: 580 ----------SSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV--PKVEP 618
+ + +A+ +PQ P+K +P P T P V PK P
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1050
Score = 33.5 bits (75), Expect = 2.3
Identities = 39/204 (19%), Positives = 61/204 (29%), Gaps = 7/204 (3%)
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHT 1616
P + E + P L + P + P+ P P T +
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGL 1676
T ++ ++ EP P +P E T + + + + P + +
Sbjct: 391 TTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 1677 KGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE----QPLPPGP 1732
K A PK P ++P P P P+ P P P+E P P P
Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 508
Query: 1733 IGTERSQRTDRGTEPGPIRPSHRP 1756
T+ T EP P P
Sbjct: 509 TTTKEPSPT-TPKEPAPTTTKSAP 531
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 119 bits (297), Expect = 4e-26
Identities = 164/638 (25%), Positives = 216/638 (33%), Gaps = 149/638 (23%)
Query: 362 QSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPP--PHRGP 419
++ +R + G + ++ P TP A A SR TE G P P P P P GP
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 420 AGNWGPPGDY------------PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERA 467
+ ++ P GG +P + A S + RA
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256
Query: 468 RRRREEEERR-MQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPK 526
+ + + +Q R K G A P+ P+AP +P+ PP++ +
Sbjct: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS--PSAPPSPSAPPSL-Q 313
Query: 527 ELPAPPAPPPASAPTP-------------ETEPEEPAQAPPAQSTPTPGVAAAPTLVSGG 573
LP+PPA PP+ A T + P P PP Q+ P +A P
Sbjct: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA--LALPPLQAPPS 371
Query: 574 GSTSSTSSGSFEASPVEP--------QLPSKEGPEPPEEVP--PPTTPPVPKVEPKGDGI 623
S S SP P Q P P PP + P PP +PPV
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---------- 421
Query: 624 GPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPP- 682
P+ PPSQ PP +APP VPPSPP
Sbjct: 422 SPSATPPSQA----------PPSL-----------------------AAPPLQVPPSPPA 448
Query: 683 -QPVTLGAVPAPQAPP-----------PPPKALYPGALGRPP----PMPPMNFDPRWMMI 726
P++ A P PQAPP PPP+A P AL PP P PP +F +
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA--PPALATPPLQALPSPPASFPGQAPFS 506
Query: 727 PPYVDPRLLQGRPPLDFYP------------PGVHPSGLVPRERSDSGGSSSEPFDRHAP 774
P P PP P P P+ PR G +S R
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 775 AMLRERGTPP--------VDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETP 826
A+ PP P LA T+TP E R D G
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-----------DSGPEGGAA 615
Query: 827 PVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPP-----GSDEVAKI-QTPP 880
PPP LA+ + P PP++ PG PLPWPP +D + I +T
Sbjct: 616 ASPPPDAELAACHPAAWSRGPAPPLAF--RGAPG-APLPWPPATGPGSADGLCTIYETEG 672
Query: 881 PKKEPPKEETAQLTGPE---AGRKPARGVGSGGQGPPP 915
P+ P GP +G K A G G+G P
Sbjct: 673 PESATPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSP 709
Score = 106 bits (265), Expect = 2e-22
Identities = 174/710 (24%), Positives = 227/710 (31%), Gaps = 127/710 (17%)
Query: 345 EDGRDSDEEGAEGHRDSQSASG--EERPPEADGKKGNSPNSEPP-TPKT-----AWAETS 396
++ RD + GA + A G RPP SP PP TP A
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPP-------GSPRPPPPVTPAALRVLGAAGAVG 54
Query: 397 RPP--ETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRK 454
R P E G P P GP PP PP K +P R
Sbjct: 55 RKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT 114
Query: 455 QSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAA 514
+ Q+ R + E + R L A +
Sbjct: 115 TRPGPLG-----------------QKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 515 PSTPAPPPAVPKELPAP------PAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPT 568
P+ P PA+ + A P P P++ P P TE + + ++ + T AA
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 569 LVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQ 628
S GG +S S +S P++ GP P P PK PKG
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKG-------- 267
Query: 629 PPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTP-VPPSPPQPVTL 687
Q L P+ PPR K A P+P PPSP P +L
Sbjct: 268 --LQALRPPQVT---PPR----------KDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 688 GAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747
+P+P A PP +LG P +F P PP PL PP
Sbjct: 313 QTLPSPPATPPSQATT---SLGSPTLQATHSFLPS----PPL---------SPLATPPPQ 356
Query: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLT 807
P+ +P L+ +PP P L+ + T +P P L
Sbjct: 357 APPALALPP--------------------LQAPPSPPASPPLS---PLATPSPQAPNALA 393
Query: 808 SPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWP 867
L QA + P PP P + S P + AP P ++ PL+ P P P
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQAP-PSLAAPPLQVP-----PSP 446
Query: 868 PGSDEVAKIQTPPPKKEPP-KEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRW 926
P S ++ TPPP+ PP QL P PA P PP
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP------ 500
Query: 927 GPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPL-- 984
G P S +P PP +A P+ P P P Q P P PD
Sbjct: 501 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 560
Query: 985 --KITKGKLGGPKETP---PNGNLSPAPRLRRDYSYERVGPTSCRGRGRG 1029
++T GP P P+ LS P L S P RG G
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSSSATSTPEELRGYDSG 609
Score = 87.0 bits (214), Expect = 2e-16
Identities = 187/773 (24%), Positives = 254/773 (32%), Gaps = 112/773 (14%)
Query: 1189 AKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGR- 1247
A L +PP P PP P++P A VG +P R G
Sbjct: 21 APGLLTPRPPGSPRPPP-----------PVTPAALRVLGAAGAVG----RKPLAERAGGI 65
Query: 1248 --AQQQDKPPRFRRLKQERENAA-RGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAA 1304
A + PR + R A+ RG P+ ++PGP + + P
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKN---TSPGPVSSPGRASGTTRPGPLGQ 122
Query: 1305 KSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGG---GGA 1361
K +S + + + E S+ RR D P P +P G G
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARR-DTSGPTPGTPSPAMARRSRAAGTEVGLP 181
Query: 1362 VPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGG----KAGSSGSSSGGGGG 1417
P SA R K +S S S RRP GG A S SSS
Sbjct: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241
Query: 1418 GPGGRTGPG-RGDKR-----SWPSPKNRS--RPPEERPP----------------GLPLP 1453
P R+GP RG R S P PK RPP+ PP P P
Sbjct: 242 SPA-RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 1454 PPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPR 1513
PPS SA L Q + S PA +Q ++ GS T H LP P P
Sbjct: 301 SAPPSPSAPPSL-QTLPSPPA---TPPSQATTSLGSPTLQATHSF----LPSPPLSPLAT 352
Query: 1514 PPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKP-ELLQ 1572
PP + P L + P +P S +SP + P LLQ
Sbjct: 353 PPPQAPPALALPPLQAPP--------------SPPASPPLSPLATPSPQAPNALAVHLLQ 398
Query: 1573 EESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWM 1632
PPP P P + S ++A L S + P S
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458
Query: 1633 EPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSP 1692
P +P +A + + +++ P SP G A P SP
Sbjct: 459 PPQAP-PPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515
Query: 1693 LNAVPCEGPPG-SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIR 1751
L P + PP + P + PP+P + PR P P GP + R PGP
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRLTLALAPGP-- 572
Query: 1752 PSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEP 1811
P PP + +S + G L S E + R ++ P A+A P
Sbjct: 573 ----PPPPSRSPSST-------LSGPDLAGHSSSATSTPEEL---RGYDSGPEGGAAASP 618
Query: 1812 QSKNLDSGHCVPEPSSSGQRLYPEVFYGSAG---PSSSQISGGAMDSQLHP-NSGGFRPG 1867
+ + C P S G P F G+ G P G+ D + G
Sbjct: 619 PP-DAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 676
Query: 1868 TPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV 1920
TP+ P L PGP+P ++ A G + + LG+LP G +
Sbjct: 677 TPA-------PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722
Score = 85.9 bits (211), Expect = 4e-16
Identities = 194/777 (24%), Positives = 255/777 (32%), Gaps = 182/777 (23%)
Query: 1446 RPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGL-- 1503
RPPG P PPPP + +A+ +V+ + A ++ LA+ + G T P PR P
Sbjct: 28 RPPGSPRPPPPVTPAAL----RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83
Query: 1504 --PQAPQGPSPRPPTRYEPQRVNS-GLSSDPHFEEPGPM-------------VRG----- 1542
P + +G P P V+S G +S PGP+ RG
Sbjct: 84 RPPASGRGERAPPAKNTSPGPVSSPGRASGT--TRPGPLGQKGLRISAEETVARGKATEA 141
Query: 1543 ------VGGTPRDSAGVSPFPPK----RRERPPRKPELLQEESLPPPHSSGFLGSKPEGP 1592
G RD++G +P P RR R E LP P S P
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG-----TEVGLPRPAPSA-------RP 189
Query: 1593 GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQ-SDS 1651
P E + + H A R RPS+ P S + T +S + S
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARR---RPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 1652 GVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSS--PLNAVPCEGPPGSEPPRR 1709
G G + + P + L+ PP++ + PL++ P P S PP
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP-- 304
Query: 1710 PPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDS 1769
P AP P Q LP P T G+ S P PP
Sbjct: 305 SPSAP--------PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP---------- 346
Query: 1770 DLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCV-----PE 1824
L + +A L +A P S S A+ PQ+ N + H + P
Sbjct: 347 -LSPLATPPPQAPPALALPPLQA-PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 1825 PSSSGQRLY-----PEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPL 1879
PS Q + P V + PS + S A Q+ P+ P +PS P P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP- 463
Query: 1880 YLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLP 1939
PP APP L PPP PA PL
Sbjct: 464 --PPLAAPPLQLAK-----------------------------PPPQ--APPALATPPL- 489
Query: 1940 DTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPA 1999
Q LPSP P GQ+ F PS + LPM P P A
Sbjct: 490 --------QALPSP------PASFPGQAPFSPSAS------LPMSPLATPP------PQA 523
Query: 2000 PPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVELKPFQ 2059
PP PL +P P P A R PP P S R +L P P
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR-LTLALAPGPPPPPSRSP-- 580
Query: 2060 DYQKLSSNLGGP-------GSSRTPPTGRSF-SGLNSRLKATPSTYSGVFRTQRVDLYQQ 2111
SS L GP ++ TP R + SG A+P + + +
Sbjct: 581 -----SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635
Query: 2112 ASPPDALR---WIPKPW-ERTGPP---------PREGPSRRAEEPGSRGDKEPGLPP 2155
+PP A R P PW TGP EGP PG+ +PG P
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA---LDPGPSP 689
Score = 83.2 bits (204), Expect = 3e-15
Identities = 167/697 (23%), Positives = 228/697 (32%), Gaps = 89/697 (12%)
Query: 1113 HESDLAPSDKEAPTPKE---GTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
++ D A + A TP G LT P P P P +PA R G V + + R
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-GRKPLAER 61
Query: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL-SPVARGGSNG 1228
G GG P+ P P S P PP+K PGP+ SP G+
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAK-----NTSPGPVSSPGRASGTTR 116
Query: 1229 GSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEE 1288
+G + R + + P R R + + + G PS PA A
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMARRSRA 173
Query: 1289 ALTTVTV---APA---------PRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRG 1336
A T V + AP+ PR++ + + + S A +A + R
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 1337 DKEAPP---PVLLTPKAVGTPGGGGGGAVP---GISAMSRGDLSQRAKDLSKR--SFSSQ 1388
A P P P A GTP + P G+ A+ ++ KD + SS
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293
Query: 1389 RPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPG----RGDKRSWPSP--KNRSRP 1442
+ P P S T G + PSP + P
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353
Query: 1443 PEERPPGLPLPP--PPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK 1500
P + PP L LPP PPS A L + +P ALA + Q + P P
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA-PNALA-VHLLQAPFSPPPSPPVQA 411
Query: 1501 PGLPQA--PQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPP 1558
P P A P PS PP++ P L P PM P+ ++ P
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471
Query: 1559 KRRERPPRKPELLQE---ESLPPPHSSGFLGSKPEGPGPQAESRDTGT--EALTPHIWNR 1613
+ + PP+ P L ++LP P +S F G P P T P +
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 1614 LHTATSRKSYRPSSMEPWMEPL-SPFEDVAGTEM----------------SQSDSGVDLS 1656
L P+ P P P V+G + S + SG DL+
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 1657 G-DSQVSSGPCSQRSSPDGGLKGAAEGPPK-------RPGGSS--PLNAVPCEGPPGSEP 1706
G S +S P R G GAA PP P S P + G PG+
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 650
Query: 1707 PRRPPPAP-----------HDGDRKELPREQPLPPGP 1732
P P P +G P L PGP
Sbjct: 651 PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687
Score = 75.1 bits (183), Expect = 7e-13
Identities = 200/848 (23%), Positives = 270/848 (31%), Gaps = 162/848 (19%)
Query: 865 PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKP----ARGVGSGGQGPPPPRRES 920
P PPGS PPP P G GRKP A G+G G P R
Sbjct: 27 PRPPGSPR------PPPPVTPAALRVLGAAGA-VGRKPLAERAGGIG-GATIPESAPRAG 78
Query: 921 RTETRWGPRPGSSRRGIPPEE----PGAPPRRAGPIKKPPP---------------PTKV 961
T T P G R P + P + P RA +P P K
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138
Query: 962 EELPPKPL-----EQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYE 1016
E P + + P P P P + + G + P S PR + +
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 1017 RVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGT--GGPN 1074
V S AR R G GG R A SR S R G + G P
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAG--GGLQRPA-SRSLSSSATPLSSPARSGPSARGTPR 255
Query: 1075 HPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQ 1134
P P S+ + +G + P+ + P K+A P G L+
Sbjct: 256 APAHP-----SQPKPKGLQALRPPQ-----------------VTPPRKDA-APALGPLSS 292
Query: 1135 VPLAPPPPGAPPSP-APARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGW--SPPAKS 1191
PLA P P APPSP AP TP PS+ G P Q + SPP
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATP---PSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 1192 LA---PKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRA 1248
LA P+ PP LPP + P P PLSP+A + + + + P
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQAP-------F 401
Query: 1249 QQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPD 1308
PP Q + PS T P+ AP P A + V P+P + SP
Sbjct: 402 SPPPSPP-----VQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSP- 454
Query: 1309 LSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTP--KAVGTPGGGGGGAVPGIS 1366
A + + + PP L TP +A+ +P G P
Sbjct: 455 -------SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507
Query: 1367 AMS-----------RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGS----S 1411
+ S + A L P ++ R P PG SG +
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 1412 SGGGGGGPGGR------TGPG-RGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFR 1464
G P R +GP G S S R + P G PPP +
Sbjct: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA----- 622
Query: 1465 LDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVN 1524
++ +PA + A + +G+ AP P P G + T YE +
Sbjct: 623 --ELAACHPAAWSRGPAPPLAFRGAPGAP------LPWPPATGPGSADGLCTIYETEGPE 674
Query: 1525 SGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPEL------------LQ 1572
S + P +PGP GG + +AG R + R EL L
Sbjct: 675 SATPA-PGALDPGPSPGTSGG--KAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLL 731
Query: 1573 EESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWM 1632
+L + G G GPG TG +R + + + W
Sbjct: 732 SRTLLLAAAEGAAGGSGGGPGGAEGGGVTG---------------GARAALSDAELGRWA 776
Query: 1633 EPLSPFED 1640
E LSP ++
Sbjct: 777 ELLSPLDE 784
Score = 73.6 bits (179), Expect = 2e-12
Identities = 146/538 (27%), Positives = 179/538 (33%), Gaps = 76/538 (14%)
Query: 1656 SGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPG------------ 1703
+G ++ S P S R K + GP PG +S G G
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 1704 --SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRP--SHRPGPP 1759
+E P+R A G R++ P P P RS+ GTE G RP S RP PP
Sbjct: 137 KATEAPKRS--ALSAGARRDTSGPTPGTPSPAMARRSRAA--GTEVGLPRPAPSARPRPP 192
Query: 1760 VQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAE-PQSKNLDS 1818
+ G S TE P +R PSA + P S++L S
Sbjct: 193 TE--------------GPRKSVSSASEHSTTEPSPAARR---RPSAGGGLQRPASRSLSS 235
Query: 1819 GHCVPEPSSSGQRLYPEVFYGSAGPSS-SQISGGAMDSQLHPN-SGGFRPGTPSLHPYRS 1876
P SS R P P+ SQ + + P + + P+L P S
Sbjct: 236 S---ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292
Query: 1877 QPLYLPPGPAPPS--ALLSGLALKGQFLDFSTMQATELGK--LPAGGVLYPPPSFLYSPA 1932
PL P APPS A S L + T LG L A P P SP
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL--SPL 350
Query: 1933 FCPSP-LPDTSLLQVRQDLPSPSDFYSTPLQP-GGQSGFLPSGAPAQQMLLPMVDSQLPV 1990
P P P L Q PSP S PL P S P+ + P P
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408
Query: 1991 VNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRP---PPAP------ATRVLPSPARPF 2041
V P PPA PP+S P+ PPSLA P PP+P + P P P
Sbjct: 409 VQ----APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Query: 2042 PASLGRAEL--HPVELKPFQDYQKLSSNLGGPGS-SRTPPTGRSFSGLNSRLKATPSTYS 2098
P + +L P + P L + P S P S S S L P
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524
Query: 2099 GVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156
V L Q P A + P PP GP P PG PPP
Sbjct: 525 PVL---AAPLLQVPPSPPASPTLQAPRR----PPTPGPDTSVSGPRLTLALAPGPPPP 575
Score = 68.6 bits (166), Expect = 6e-11
Identities = 145/687 (21%), Positives = 206/687 (29%), Gaps = 183/687 (26%)
Query: 106 PESQPLPASQTPASNQPKRPPAAPENT-----------------PLVPSGVKSWAQASVT 148
P + P S+ PAS + +R P A + PL G++ A+ +V
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 149 HGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSS--GPGPSLRP----- 201
G + + S+L + R+ A + R + + P PS RP
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 202 ----------QNSTT----------WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPP 241
++STT GG + P S R G G P
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 254
Query: 242 QFPPY---------RGMMPPFMYPPYLPFPPPYGP--------QGPYRYPTPDGPSRFPR 284
+ P + + + PP + PP P GP P P+P P
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314
Query: 285 VAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDE 344
+ P + PP + +G P++
Sbjct: 315 LPSPPAT-PPSQATTSLGSPTL-------------------------------------- 335
Query: 345 EDGRDSDEEGAEGHRDSQSASGEERPP-EADGKKGNSPNSEPPTPKTAWAETSRPPETEP 403
+ S S PP +A P PP+P A P P
Sbjct: 336 --------QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP---ASPPLSPLATP 384
Query: 404 GPPAPK---------PPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRK 454
P AP P PPP + PP P P PP+ A +
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQV 442
Query: 455 QSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAA 514
S S + + A + AP +L A+P PP A
Sbjct: 443 PPSPPASPPM-------------------SPSATPPPQAPPPLAAPPLQL-AKP--PPQA 480
Query: 515 PSTPAPPPAVPKELPAPPAPPPASAP-TPETE-PEEPAQAPPAQSTPTPGVAAAPTLVSG 572
P A PP + LP+PPA P AP +P P P PP Q+ P V AAP L
Sbjct: 481 PPALATPPL--QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP---VLAAPLL--- 532
Query: 573 GGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVE---PKGDGIGPTRQP 629
+ P P P+ + P P P T+ P++ G P+R P
Sbjct: 533 ------------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580
Query: 630 PSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGA 689
S G P ++ + +G A +P PP
Sbjct: 581 SSTLSG---------PDLAGHSSSATSTPEELRGYDSGPEGGAAASP----PPDAELAAC 627
Query: 690 VPAPQAPPPPPKALYPGALGRPPPMPP 716
PA + P P + GA G P P PP
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPP 654
Score = 50.8 bits (120), Expect = 1e-05
Identities = 94/362 (25%), Positives = 115/362 (31%), Gaps = 54/362 (14%)
Query: 103 AQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLL 162
A PP P PA P P PPA+P +PL ++ A H L
Sbjct: 351 ATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVH----------LLQ 398
Query: 163 SRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRP---QNSTTWRDGGGRGPDELE 219
+ FS P +QA + SA S PSL Q + P
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458
Query: 220 GPDSKLHHGHDPRGGLQPSGPPQFPPYRGM-------MPPFMYPPYLPFPPPYG-PQGPY 271
P + P +P PPQ PP PP +P PF P P P
Sbjct: 459 PPQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516
Query: 272 RYPTPDGPSRFPRVAGPRGSGPPMRLVEPV----GRPSILKEDNLKEFDQLDQENDDGWA 327
P P P P +A P PP P RP D +L G
Sbjct: 517 ATPPPQAP---PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573
Query: 328 GAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPT 387
S G D GH S +++ EE G +G + S PP
Sbjct: 574 PPPSRSP-------SSTLSGPD-----LAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621
Query: 388 PK------TAWAETSRPPETEPGPPAPKPPLP-PPHRGPAGNWGPPGDYPDRGGPPCKPP 440
+ AW+ PP G AP PLP PP GP G Y + GP P
Sbjct: 622 AELAACHPAAWSRGPAPPLAFRG--APGAPLPWPPATGPGSADGLCTIY-ETEGPESATP 678
Query: 441 AP 442
AP
Sbjct: 679 AP 680
Score = 45.1 bits (105), Expect = 8e-04
Identities = 74/307 (24%), Positives = 109/307 (35%), Gaps = 59/307 (19%)
Query: 5 SGPTAKGKDGKKYSSLNLFDTY-KGKSLEIQKPAV----------APRHGLQSLGKVAIA 53
SG T G G+K ++ +T +GK+ E K + P G S +
Sbjct: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 171
Query: 54 RRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDP------KSSDASTAQPPE 107
R LP + P P+ AS+ ++P + S Q P
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229
Query: 108 SQPLPASQTPASNQPKRPPAAPENTPLVPS--------GVKSWAQASVT----HGAHGDG 155
S+ L +S TP S+ + P+A TP P+ G+++ VT A G
Sbjct: 230 SRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
Query: 156 GRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGP 215
+SS L+ S P+ A + Q+ P+ P +TT
Sbjct: 289 PLSSSPLATPSPSAPPSPSA-----------PPSLQTLPSPPATPPSQATT--------- 328
Query: 216 DELEGPDSKLHHGHDPRGGLQP--SGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRY 273
L P + H P L P + PPQ PP +PP PP P PP P
Sbjct: 329 -SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA-LPPLQAPPSPPASPPLSPLAT--- 383
Query: 274 PTPDGPS 280
P+P P+
Sbjct: 384 PSPQAPN 390
Score = 42.7 bits (99), Expect = 0.004
Identities = 63/269 (23%), Positives = 84/269 (31%), Gaps = 27/269 (10%)
Query: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
PP PSL A P+ P + P ++ P Q PA T
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486
Query: 117 PASNQPKRPPAA-PENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQA 175
P PPA+ P P PS + + A L S PTLQA
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 176 A------GDQDKAAKERESAEQSSGPGP--SLRPQNSTTWRDGGGRGPDELEGPDSKLHH 227
G + R + + GP P S P ++ + D G P+ +
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 228 GHDPRGGLQPSGPPQFPP--------YRGMMPPFMY----PPYLPFPPPYGPQGPYRYPT 275
P GG S PP RG PP + LP+PP GP +
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP------GS 660
Query: 276 PDGPSRFPRVAGPRGSGPPMRLVEPVGRP 304
DG GP + P ++P P
Sbjct: 661 ADGLCTIYETEGPESATPAPGALDPGPSP 689
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 118 bits (295), Expect = 7e-26
Identities = 330/1327 (24%), Positives = 427/1327 (32%), Gaps = 246/1327 (18%)
Query: 542 PETEPEEPAQAP-----PAQSTPTPGVAAAPTLVSGG-GSTSSTSSGSFEASPVEPQLPS 595
P P Q P P P A P + G G + G P P+ P+
Sbjct: 241 PHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPA 300
Query: 596 KE-GPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKSLPPRFQRQQQE 653
GP + P P P + P G+ P S G G P LP RF +
Sbjct: 301 GLIGPPGIQGNPGPVGDPGERGPPGRAGL-----PGSDGAPGPPGTSLMLPFRFGSGGGD 355
Query: 654 Q---LLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGR 710
+ + Q+ Q Q Q A PP P+ P P P P G G
Sbjct: 356 KGPVVAAQEAQAQAILQQARLALR-----GPPGPMGYTGRPGPLGQPGSPGL--KGESGD 408
Query: 711 PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFY-----PPGVHPS----GL--VPRE-- 757
P P P+ + PP R +GR D PGV GL +P E
Sbjct: 409 LGPQGPRG--PQGLTGPPGKAGR--RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464
Query: 758 -RSDSG-----GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLR 811
R D+G G E +R + RG P +G P P P P
Sbjct: 465 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP--KGPPGIPGP---PGV 519
Query: 812 QAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSD 871
+ D S P P PP PG G PGP + P E GP+ P PG
Sbjct: 520 RGMDGPQGPKGSLGPQGEPGPPGQQGTPG--TQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577
Query: 872 EVAKIQTPPPKKEPPKEETAQ-LTGPEA-----GRKPARGVGS-----GGQGPPPPRRES 920
P K+ PP + Q +GP+ G + +GV G +G
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 637
Query: 921 RTETRWGPRPGSSRRGIP----PEEPGAPPRRAGPIKKPPPPTKVEE-----LPPKPLEQ 971
+ G + G+P + P P R GP P PP + E +P P
Sbjct: 638 GFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYP 697
Query: 972 GDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEY 1031
G + PK G LG P +G + GPT RG+ RG
Sbjct: 698 GRQGPK-----------GSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ-RGPR 745
Query: 1032 FARGR-GFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASETR 1088
A G+ G +GT GG G E RG G G G GP PP P G+
Sbjct: 746 GATGKSGAKGTSGGDGPHGPPGE-------RGLPGPQGPNGFPGPKGPPGPPGK------ 792
Query: 1089 SEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV-----PLAPPPPG 1143
+ +P QRG E G + P P G + P P PPG
Sbjct: 793 ------DGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 845
Query: 1144 APPSPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGP 1201
P A G P G P + G G G P + PG + L + P+GP
Sbjct: 846 EQGLPGTAGKEGTKGDPGPP-GAPGKDGPAGLRGFPGERGLPG-TAGGPGLKGNEGPSGP 903
Query: 1202 LPPSKEPLKEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRL 1260
PGP SP RG + G +G GR Q P
Sbjct: 904 -------------PGPAGSPGERGAAGSGGPIGPP----------GRPGPQGPPGAAGEK 940
Query: 1261 KQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE 1320
E G G+ + P PGP A P ++ ++ D+
Sbjct: 941 GVPGEKGPIGPTGRDGVQGPVGLPGP-----------------AGPPGVAGEDGDKG--- 980
Query: 1321 WETASESSDFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD 1379
E T +G+ P PP + P VG PG G PG +G + D
Sbjct: 981 -EVGDPGQKGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEPGARG-PQGHFGAKG-D 1035
Query: 1380 LSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNR 1439
R F+ PG PGP G+ G +G G GP G GP + N
Sbjct: 1036 EGTRGFNGP-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP---------AGPNG 1085
Query: 1440 SRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRH 1499
+ P+ P G+ PP + S GIQ + V P G
Sbjct: 1086 ADGPQGPPGGVGNLGPPGEKG------EPGESGSPGIQG--------EPGVKGPRGERGE 1131
Query: 1500 K--PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM----VRGVGGTPRDSA-- 1551
K G P P P P+ PT + + N G P +PGP RG G D
Sbjct: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG--DPGPPGEGGPRGQDGAKGDRGED 1189
Query: 1552 ---GVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSK----------------PEGP 1592
G P E P P L + P S G G K P GP
Sbjct: 1190 GEPGQPGSPGPTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP 1248
Query: 1593 -GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDS 1651
GP + G L + + + ++ P + P L AG + +
Sbjct: 1249 AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--PGLPGLRGDAGAKGEKGHP 1306
Query: 1652 GV----------DLSGDSQVSSGPCSQRSSPDGGLKGAAE-----GPPKRPGGSSPLNAV 1696
G+ GD + S + G+ GA+ GPP PG + P A
Sbjct: 1307 GLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAK 1366
Query: 1697 PCEGP--PGSEPPRRPPPAPHDGDRKELPREQPLP-PGPIGTERSQRTDR-GTEPGPIRP 1752
GP P E + PP H G E+ QPLP P T RS R E I
Sbjct: 1367 GATGPGGPKGEKGVQGPPG-HPGPPGEV--IQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1423
Query: 1753 SHRPGPP 1759
PG P
Sbjct: 1424 GGAPGSP 1430
Score = 111 bits (277), Expect = 9e-24
Identities = 332/1404 (23%), Positives = 437/1404 (31%), Gaps = 288/1404 (20%)
Query: 187 ESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPY 246
E E G RPQN R R P + S+LH + Q + P+
Sbjct: 222 EQKELECEGGQRERPQNQQPHR--AQRSPQQ---QPSRLHRPQNQEPQSQAAHGPRGLKG 276
Query: 247 RGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGS-GPPMRLVEPVGRPS 305
P + P L PP GP+GP P G P G G GPP R P
Sbjct: 277 EKGEPAVLEPGMLVEGPP-GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLP----- 330
Query: 306 ILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSAS 365
G GA + L F G D A +Q+
Sbjct: 331 -------------------GSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAIL 371
Query: 366 GEER-----PPEADGKKGN-SPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGP 419
+ R PP G G P +P +P + E G P+ P RGP
Sbjct: 372 QQARLALRGPPGPMGYTGRPGPLGQPGSPGL---------KGESGDLGPQGP-----RGP 417
Query: 420 AGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRM- 478
G GPPG RG D + R L E+ R +
Sbjct: 418 QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP-GLPGEKGHRGDTGAQGLPG 476
Query: 479 ---QEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPP 535
++ R E R G P + P P P PP + + P P
Sbjct: 477 PPGEDGERGDDGEIGPR-----GLPGESGPRGLLGPKGPPGIPGPPGV--RGMDGPQGPK 529
Query: 536 PASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPS 595
+ P E P P Q P P A P G S P P
Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPH--GEKGPQGKPGLPGMPGSDGPPGHPG 587
Query: 596 KEGPEPPEEVPPPTTP--PVPKVEPKG----DGI-GPTRQPPSQGL-GYPKYQKSLPPRF 647
KEGP + P+ P P+ P+G DGI G +G G+P ++ + +
Sbjct: 588 KEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKG 647
Query: 648 QRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGA 707
R E + + + +G PT P P G + P P P + G+
Sbjct: 648 DRG--EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 705
Query: 708 LGRPPPMPPMNFD-----------PRWMMIPP----YVDPRLLQGRPPLDFYPPGVHPSG 752
LG P P + + PR P PR G+ G P G
Sbjct: 706 LGFPG-FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 764
Query: 753 LVPRERSDSG--GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPL 810
P ER G G + P + P + G P + VG P P + P
Sbjct: 765 -PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 823
Query: 811 RQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGS 870
A + G R P PP PP E G PG +PGP P PG
Sbjct: 824 GAAGETGPMGERGH--PGPPGPP--------GEQGLPGTAGKEGTKGDPGP---PGAPGK 870
Query: 871 DEVAKIQTPPPKKEPP----------KEETAQLTGPEAGRKPARGV-GSGGQGPPPPRRE 919
D A ++ P ++ P E + GP AG RG GSGG PP R
Sbjct: 871 DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP-AGSPGERGAAGSGGPIGPPGRPG 929
Query: 920 SRTETRWGPRPGSSRRGIPPEE-PGAPPRR---AGPIKKPPPPTKVEELPPKPLEQGDET 975
+ GP + +G+P E+ P P R GP+ P P P G++
Sbjct: 930 PQ-----GPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP-------PGVAGEDG 977
Query: 976 PKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARG 1035
K DP + KG G E P G P + + + G RG +G + A+G
Sbjct: 978 DKGEVGDPGQ--KGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP-QGHFGAKG 1034
Query: 1036 ----RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG-----GPNHPPAPRGRTA-- 1084
RGF G G G + G G G TG GP PP PRG
Sbjct: 1035 DEGTRGFNGPPGPIG----------LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084
Query: 1085 ------------------------SETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPS 1120
E+ S G + E K R E G + P
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144
Query: 1121 DKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRG-RGGGRPPP 1179
+ PT +G P P G P P P GG PRG +G RG P
Sbjct: 1145 GPKGPTGDDGPKGN----PGPVGFPGDPGPP---GEGG----PRGQDGAKGDRGEDGEPG 1193
Query: 1180 QVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKE--------KLIPGPLSPVARGGSNGGSN 1231
Q PG P P P G P+ P E K PG + + G G +
Sbjct: 1194 Q--PGSPGPTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1250
Query: 1232 VGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALT 1291
+ G R G QQ +P A G G P P PG
Sbjct: 1251 PAGKPGPDGLRGLPGSVGQQGRP------------GATGQAGPPGPVGPPGLPGLR---- 1294
Query: 1292 TVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAV 1351
A + P L + +GD+ P P
Sbjct: 1295 ----GDAGAKGEKGHPGLIGLIGPPGEQG-------------EKGDRGLPGPQ------- 1330
Query: 1352 GTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSS 1411
G+PG G +PG S G + PG+ PGP G G+ G++
Sbjct: 1331 GSPGQKGEMGIPGAS----GPIGPGGP-----------PGL------PGPAGPKGAKGAT 1369
Query: 1412 SGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPS-----SSAVFRLD 1466
G GGP G G P PP E LP+ P + S + + D
Sbjct: 1370 ---GPGGPKGEKGV--------QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQED 1418
Query: 1467 QVIHS-----NPAGIQQALAQLSS 1485
+ I + +P G+++ L S
Sbjct: 1419 EAIPTGGAPGSPGGLEEIFGSLDS 1442
Score = 105 bits (262), Expect = 5e-22
Identities = 291/1206 (24%), Positives = 386/1206 (32%), Gaps = 238/1206 (19%)
Query: 640 QKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP 699
Q P R QR Q+Q + + + Q + P + +P L + PP P
Sbjct: 237 QNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGP 296
Query: 700 --PKALY--PGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVP 755
P L PG G P P+ P P G P D PG + L+
Sbjct: 297 EGPAGLIGPPGIQGNPGPVGD----------PGERGPPGRAGLPGSDG-APGPPGTSLML 345
Query: 756 RERSDSGGSSSEPF----DRHAPAMLRE-----RGTP--------------PVDPKLAWV 792
R SGG P + A A+L++ RG P P P L
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405
Query: 793 -GDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPI 851
GD+ P P+ LT P +A G ++ P P + GF +G PG P
Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRRGRAG--ADGARGMPGDPGVKGDRGF--DGLPGLPG 461
Query: 852 SRFPLEEPGPRPLPWPPGSD-EVAKIQTPPPKKEPPKEETAQLTGPEA--GRKPARGVGS 908
+ + G + LP PPG D E P+ P + L GP+ G GV
Sbjct: 462 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGV-R 520
Query: 909 GGQGPPPPRRESRTETRWGPRPGSS----RRGIP-PEEPGAPPRRAGPIKKPPPPTKVEE 963
G GP P+ + GP PG +G+P P+ P GP KP
Sbjct: 521 GMDGPQGPKGSLGPQGEPGP-PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG------- 572
Query: 964 LPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTS 1022
LP P G P P + TKG G + P G L P PR + G
Sbjct: 573 LPGMPGSDGP--PGHPGKEGPPGTKGNQG---PSGPQGPLGYPGPRGVKGVD----GIRG 623
Query: 1023 CRGRGRGEYFARG-RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GPNHPPAP 1079
+G +GE G GF+G G +G R RG+DG G G GP P P
Sbjct: 624 LKGH-KGEKGEDGFPGFKGDIGVKG----DRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678
Query: 1080 RGRTASETRSEGSEYEEIPKRRRQRGSE-----TGSETHESDLAPSDKEAPTPKEGTLTQ 1134
G + + P R+ +GS G+ + S K P + G
Sbjct: 679 PGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG---- 734
Query: 1135 VPLAPPPPGAPPSPAPARFTARGGRVFT-----PRGVPSRRGRGGGRPPPQVCPGWSPPA 1189
P G P T + G T P G P RG PG P
Sbjct: 735 ------PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG----------LPGPQGPN 778
Query: 1190 KSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQ 1249
PK PP PP K+ L P P RG VG +
Sbjct: 779 GFPGPKGPPG---PPGKDGL-------PGHPGQRG------EVGFQ-------------- 808
Query: 1250 QQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDL 1309
G G P + P A G P R P
Sbjct: 809 -----------------GKTGPPGPPGVVGPQGAAGE--------TGPMGERGHPGPPGP 843
Query: 1310 SNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMS 1369
+ + T+ + G K P P P A G G G PG
Sbjct: 844 PGE-------------QGLPGTAGKEGTKGDPGP----PGAPGKDGPAGLRGFPG----- 881
Query: 1370 RGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG----P 1425
+ L + G E + PGP G G G++ GG GP GR G P
Sbjct: 882 -------ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 934
Query: 1426 GRGDKRSWPSPKN----RSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALA 1481
G ++ P K R + P GLP P PP + D+ +P Q+
Sbjct: 935 GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDG-DKGEVGDPG--QKGTK 991
Query: 1482 QLSSRQGSVTAPGG-HPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM- 1539
G PG P +PG A P R P + + + G PGP+
Sbjct: 992 GNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG--FNGPPGPIG 1049
Query: 1540 ---VRGVGGTPRDSAGVSPFPPKRRERP--PRKPELLQEESLPP--------------PH 1580
+ G G ++ V P P P P P PP P
Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109
Query: 1581 SSGFLGSKPE----GP-GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPL 1635
SG G + E GP G + E ++G + T P + +P
Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169
Query: 1636 SPFE-DVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLN 1694
P E G + ++ D G D S GP + + P G L GP PG
Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE-NGPPGPL--GKRGPAGSPGSEGRQG 1226
Query: 1695 AVPCEGPPGS--EPPRRPPPAPHDGDRKELPREQPLPPGPIGTE-RSQRTDRGTEPGPIR 1751
+G PG+ P + P P K P PG +G + R T + PGP+
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG 1286
Query: 1752 PSHRPG 1757
P PG
Sbjct: 1287 PPGLPG 1292
Score = 99.4 bits (246), Expect = 3e-20
Identities = 321/1342 (23%), Positives = 424/1342 (31%), Gaps = 240/1342 (17%)
Query: 353 EGAEGHR-DSQSASGEERPPEADGKKGNSPNSEPPT------PKTAWAETSRPPETEPGP 405
EG + R +Q +R P+ + + P ++ P P+ E P EPG
Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGM 288
Query: 406 PAPKPPLPPPHRGPAGNWGPPG--------DYPDRGGPPCKPPAPEDEDEAWRQRRKQSS 457
PP P GPAG GPPG P GPP + P +
Sbjct: 289 LVEGPPGP---EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP-----GPPG 340
Query: 458 SEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPST 517
+ + L ++ +E +A + RL + G P P P +
Sbjct: 341 TSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR-GPPGPMGYTGRPGPLGQPGS 399
Query: 518 PAPPPAVPKELP-APPAPPPASAPTPETEPEEPAQAPPAQSTP-TPGVA------AAPTL 569
P P P P + P + A A A+ P PGV P L
Sbjct: 400 PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGL 459
Query: 570 VSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQP 629
G T + P E +G P +P + P + PKG G P
Sbjct: 460 PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR-GLLGPKGPP-GIPGPP 517
Query: 630 PSQGLGYPKYQK-SLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLG 688
+G+ P+ K SL P Q QQG+ P T P P +
Sbjct: 518 GVRGMDGPQGPKGSLGP--------------QGEPGPPGQQGT-PGTQGLPGPQGAIGPH 562
Query: 689 AVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV 748
PQ P P PG+ G PP P P P+ G P P GV
Sbjct: 563 GEKGPQGKPGLPG--MPGSDG-PPGHPGKEGPPGTKGNQGPSGPQGPLGYPG----PRGV 615
Query: 749 HPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
+ + G + F P + G ++ G P P+ T
Sbjct: 616 KGVDGIRGLKGHKGEKGEDGF----PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671
Query: 809 PLRQAADEDDKGMRSETPPVPPP----------PPYLASYPGFPENGAPGPPISRFPLEE 858
P D G+ E + P P +PGFP GA G +R +
Sbjct: 672 P---TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFP--GASGEKGARGLSGK 726
Query: 859 PGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRR 918
GPR P G P + P+ T G+ A+G SGG GP P
Sbjct: 727 SGPRGERGPTG----------PRGQRGPRGAT--------GKSGAKGT-SGGDGPHGP-- 765
Query: 919 ESRTETRWGPRPGSSRRGIP-PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDE--T 975
PG RG+P P+ P P GP K PP P + LP P ++G+
Sbjct: 766 -----------PG--ERGLPGPQGPNGFP---GP-KGPPGPPGKDGLPGHPGQRGEVGFQ 808
Query: 976 PKPPKPDPLKITKGKLGGPKETPPNGNLS-PAPRLRRDYSYERVGPTSCRGRGRGEYFAR 1034
K P P + G G ET P G P P GP +G
Sbjct: 809 GKTGPPGPPGVV-GPQGAAGETGPMGERGHPGP----------PGPPGEQGLPGTAGKEG 857
Query: 1035 GRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG-----GPNHPPAPRGRTASETRS 1089
+G G G G+ + R + RG G GG G GP+ PP P G + E +
Sbjct: 858 TKGDPGPPGAPGKDGPA-GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG-SPGERGA 915
Query: 1090 EGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA 1149
GS P R G+ + PT ++G Q P+ P P PP A
Sbjct: 916 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDG--VQGPVGLPGPAGPPGVA 973
Query: 1150 PARFTARGGRVFTP--RGVPSRRG-RGGGRPPPQVCPGWSPPAKSLAPKKPPTGPL---- 1202
G V P +G +G G PP + P P A + GP
Sbjct: 974 GE--DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031
Query: 1203 ------------PPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQ 1250
PP P+ + +PGP G G G R +G
Sbjct: 1032 AKGDEGTRGFNGPPG--PIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGP 1089
Query: 1251 QDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLS 1310
Q P L E G G P + PG K P
Sbjct: 1090 QGPPGGVGNLGPPGEKGEPGESGSPGI---QGEPG------------------VKGPRGE 1128
Query: 1311 NQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSR 1370
++ + E + G K P PV P G PG GG G ++
Sbjct: 1129 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF-PGDPGPPGEGGPRGQDG----AK 1183
Query: 1371 GDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGK---AGSSGSSSGGGG----GGPG--- 1420
GD + + S PG +N PGP GK AGS GS GG G PG
Sbjct: 1184 GDRGEDGEPGQPGS-----PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIG 1238
Query: 1421 --GRTGP-GRGDKRSWPSPK----------NRSRPPEERPPGLPLPPPPPSSSAVFRLD- 1466
G+TGP G P P + RP G P P PP + R D
Sbjct: 1239 APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL-RGDA 1297
Query: 1467 ----QVIHSNPAGIQQALAQLSSR-QGSVTAPGGHPRHK--PGLPQA--PQGPSPRP--P 1515
+ H G+ + + + P G P K G+P A P GP P P
Sbjct: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1357
Query: 1516 TRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGV-SPFP---PKRRERPPRKPELL 1571
P+ E G V+G G P V P P PK+ R L+
Sbjct: 1358 GPAGPKGAKGATGPGGPKGEKG--VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLM 1415
Query: 1572 QEESLPPPHSSGFLGSKPEGPG 1593
QE+ P G P PG
Sbjct: 1416 QEDEAIP------TGGAPGSPG 1431
Score = 92.0 bits (227), Expect = 5e-18
Identities = 280/1149 (24%), Positives = 360/1149 (31%), Gaps = 238/1149 (20%)
Query: 211 GGRGPDELEG-PDSKLHHGHDPRGGLQPSGPPQFPPYRG---MMPPFMYPPYLPFPPPYG 266
G RG D L G P K H G GL GPP RG + P P G
Sbjct: 449 GDRGFDGLPGLPGEKGHRGDTGAQGLP--GPPGEDGERGDDGEIGPRGLPGESGPRGLLG 506
Query: 267 PQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGW 326
P+GP P P G GP+GS P P G+ L G
Sbjct: 507 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL--------PGPQGA 558
Query: 327 AGAHEEVDYTEK-----LKFSDEEDGRDSDEEGAEGHRDSQSASGEERP---PEADGKKG 378
G H E K + SD G +EG G + +Q SG + P P G KG
Sbjct: 559 IGPHGEKGPQGKPGLPGMPGSDGPPGHPG-KEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 617
Query: 379 ----------NSPNSEPPTP--------KTAWAETSRP-PETEPGPPAPK-------PPL 412
E P K E P E GP PK P
Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677
Query: 413 PPPHRGPAGNWGPPG--DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRR 470
PP G G G PG YP R GP P + + + S + R
Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK-----SGPRGE 732
Query: 471 REEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPA 530
R R Q R A K GA P PP P P P P
Sbjct: 733 RGPTGPRGQRGPRGATG--------KSGAKGTSGGDGPHGPPGERGLPGPQG--PNGFPG 782
Query: 531 PPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
P PP P + P P Q G P +V G+ T P
Sbjct: 783 PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840
Query: 591 PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQ 650
P P ++G +P K +P G P + P+ G+P ++ LP
Sbjct: 841 PGPPGEQG------LPGTAGKEGTKGDPGPPG-APGKDGPAGLRGFPG-ERGLP------ 886
Query: 651 QQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ--------PVTLGAVPAPQAPPPPPKA 702
+ ++ S PP P SP + P+ P PQ PP A
Sbjct: 887 ------GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG--PPGAA 937
Query: 703 LYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
G G P+ P D +QG P+ P P V E D
Sbjct: 938 GEKGVPGEKGPIGPTGRDG-------------VQG--PVGLPGPAGPPG--VAGEDGDK- 979
Query: 763 GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMR 822
G +P + E G P + VG A P + D+G R
Sbjct: 980 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039
Query: 823 SETPPVPPPPPYLASYPG----------FPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
PP P L PG G PGPP R P G PPG
Sbjct: 1040 GFNG--PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG-- 1095
Query: 873 VAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG----VGSGGQ----GPPPPRRESRTET 924
V + P K EP + + + G E G K RG G GQ GPP P+ + +
Sbjct: 1096 VGNLGPPGEKGEPGESGSPGIQG-EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD- 1153
Query: 925 RWGPR-----------PGSSRRGIPPEEPGA-----------PPRRAGPIKKPPPPTKVE 962
GP+ PG G P + GA P GP + PP +
Sbjct: 1154 --GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211
Query: 963 ELPP--KPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP 1020
+ P P +G + K K DP G +G P +T P G PA + GP
Sbjct: 1212 KRGPAGSPGSEGRQGGKGAKGDP-----GAIGAPGKTGPVGPAGPA---------GKPGP 1257
Query: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080
RG G+ G +GR G G+ G G P P
Sbjct: 1258 DGL------------RGLPGSVGQQGR-------------PGATGQAGPPGPVGPPGLPG 1292
Query: 1081 GRTASETRSEGSEYEEI-----PKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV 1135
R + + E I P + ++G P + +P K
Sbjct: 1293 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG---------LPGPQGSPGQKGEMGIPG 1343
Query: 1136 PLAPPPPGAPPS-PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAP 1194
P PG PP P PA +G + T G P +G G + PP PG PP + + P
Sbjct: 1344 ASGPIGPGGPPGLPGPA--GPKGAKGATGPGGP--KGEKGVQGPPG-HPG--PPGEVIQP 1396
Query: 1195 -----KKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG--GSNVGMEDGERPRRRRHGR 1247
K + S+ +++ IP +P + GG GS + + RR G
Sbjct: 1397 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTG- 1455
Query: 1248 AQQQDKPPR 1256
QD P R
Sbjct: 1456 --TQDSPAR 1462
Score = 90.5 bits (223), Expect = 2e-17
Identities = 310/1352 (22%), Positives = 425/1352 (31%), Gaps = 303/1352 (22%)
Query: 818 DKGMRSETPPVPPPPPYLASYPGFPENGAP-GPPISRFPLEE---PGPRPLPWPPGSDEV 873
+ GM E PP P P L PG N P G P R P PG P PPG+ +
Sbjct: 285 EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLM 344
Query: 874 AKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSS 933
+ G G G +GP +E++ + + +
Sbjct: 345 LPFRF--------------------------GSGGGDKGPVVAAQEAQAQAIL-QQARLA 377
Query: 934 RRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPK-PDPLKITKGKLG 992
RG P P R GP+ +P P E GD P+ P+ P L GK G
Sbjct: 378 LRG--PPGPMGYTGRPGPLGQPGSPGLKGE-------SGDLGPQGPRGPQGLTGPPGKAG 428
Query: 993 GPKETPPNG--NLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGAR 1050
+G + P ++ D ++ G G +G RG G +G
Sbjct: 429 RRGRAGADGARGMPGDPGVKGDRGFD--GLPGLPGE---------KGHRGDTGAQGLPGP 477
Query: 1051 SREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGS 1110
E RGDDG G G P PRG + IP RG + G
Sbjct: 478 PGEDGE----RGDDGEIGPRGLPGES-GPRGLLGPKGPPG------IPGPPGVRGMD-GP 525
Query: 1111 ETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRR 1170
+ + L P + P ++GT PG P P G P+G P
Sbjct: 526 QGPKGSLGPQGEPGPPGQQGT----------PGTQGLPGPQGAIGPHGEK-GPQGKPGLP 574
Query: 1171 GRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGS 1230
G G PP PP K GP GP P+ G G
Sbjct: 575 GMPGSDGPPGHPGKEGPPGT-----KGNQGP-------------SGPQGPLGYPGPRGVK 616
Query: 1231 NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPE--E 1288
V DG R + G + +D P F+ + +G G+ + GPE +
Sbjct: 617 GV---DGIRGLKGHKGE-KGEDGFPGFKG-----DIGVKGDRGEVGVPGSRGEDGPEGPK 667
Query: 1289 ALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTP 1348
T T P P P L + K P + P
Sbjct: 668 GRTGPTGDPGP-------PGLMGEKG-----------------------KLGVPGLPGYP 697
Query: 1349 KAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSS 1408
G G G PG S + A+ LS +S G + GP G G S
Sbjct: 698 GRQGPKGSLGFPGFPGASG------EKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKS 751
Query: 1409 GSSSGGGGGGPGGRTG----PGRGDKRSWPSPKNRSRPP-EERPPGLPL----------- 1452
G+ GG GP G G PG +P PK PP ++ PG P
Sbjct: 752 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKT 811
Query: 1453 -PPPPP-------SSSAVFRLDQVIHSNPAGI--QQALAQLSSRQGSVTAPGGHPRHKPG 1502
PP PP ++ + + H P G +Q L + ++G+ + PG
Sbjct: 812 GPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT--------KGDPG 863
Query: 1503 LPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFE-EPGPM-VRGVGGTP--RDSAGVS-PFP 1557
P AP P + +R G + P + GP G G+P R +AG P
Sbjct: 864 PPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIG 923
Query: 1558 PKRRERPPRKPELLQEESLP-------PPHSSGFLGSK----PEGP-GPQAESRDTGTEA 1605
P R P P E+ +P P G G P GP G E D G
Sbjct: 924 PPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVG 983
Query: 1606 LTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFED-------------VAGTEMSQSDSG 1652
+ + P + P +P + D G E ++ +G
Sbjct: 984 DPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1043
Query: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPP- 1711
Q GP ++ GPP G + P A +GPPG PP
Sbjct: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103
Query: 1712 ---------------------PAPHDGDRKELPRE-QPLPPGPIGTERSQRTDRGTE--P 1747
P G++ E + +P PPGP G D G + P
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG----DDGPKGNP 1159
Query: 1748 GPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAA 1807
GP+ PGPP + G +D GD D E P
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDG----AKGDR-----------------GEDGE--PGQPG 1196
Query: 1808 SAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPG 1867
S P +N P G+R G AG S+ G ++ P + G PG
Sbjct: 1197 SPGPTGEN-------GPPGPLGKR-------GPAGSPGSEGRQGGKGAKGDPGAIG-APG 1241
Query: 1868 TPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSF 1927
P GPA P+ L+G L S Q G+ A G PP
Sbjct: 1242 KTG-----------PVGPAGPAGKPGPDGLRG--LPGSVGQQ---GRPGATGQAGPPGP- 1284
Query: 1928 LYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPG--GQSGFL-PSGAPAQQMLLPMV 1984
P P D + + P P + G G G P G+P Q+ + +
Sbjct: 1285 -VGPPGLPGLRGDAG-AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1342
Query: 1985 DSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPP---PAPATRVLPSPARPF 2041
+ P + G P P PA P + GP V+ P P P V+ +P
Sbjct: 1343 GASGP-IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI----QPL 1397
Query: 2042 PASLGRAELHPVELKPFQDYQKLSSNLGGPGS 2073
P + + V+ + G PGS
Sbjct: 1398 PIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS 1429
Score = 64.3 bits (155), Expect = 1e-09
Identities = 146/590 (24%), Positives = 188/590 (31%), Gaps = 89/590 (15%)
Query: 1238 ERPRRRRHGRAQQ--QDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTV 1295
ERP+ ++ RAQ+ Q +P R R Q +E ++ + G L P E V
Sbjct: 234 ERPQNQQPHRAQRSPQQQPSRLHR-PQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEG 292
Query: 1296 APAPRRAAAK-SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354
P P A P N + E G P L+ P G+
Sbjct: 293 PPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSG 352
Query: 1355 GGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGG 1414
GG G V A ++ L Q L PG RPGP G+ GS G
Sbjct: 353 GGDKGPVVAAQEAQAQAILQQARLALRGP------PGPMGYTGRPGPLGQPGSPGLKGES 406
Query: 1415 GGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVI----H 1470
G GP G GP +G R R + G+P P L + H
Sbjct: 407 GDLGPQGPRGP-QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH 465
Query: 1471 SNPAGIQQALAQLSSRQGSVTAPGG-HPRHKPGLPQ-----APQGPS--PRPPT---RYE 1519
G Q L G G PR PG P+GP P PP
Sbjct: 466 RGDTGAQ-GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 524
Query: 1520 PQRVNSGLSSDPHFEEPGPMVR----GVGGTPRDSAGVSPFPPKRRERPPRKPELLQEES 1575
PQ L EPGP + G G P + P K + P P + +
Sbjct: 525 PQGPKGSLGPQG---EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581
Query: 1576 LP-------PPHSSGFLG-SKPEGP----GPQAESRDTGTEALTPHIWNRLHTATSRKSY 1623
P PP + G G S P+GP GP+ G L H
Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH-------------- 627
Query: 1624 RPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG-----GLKG 1678
E + F+ G + + + GV S GP R+ P G GL G
Sbjct: 628 ---KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP-KGRTGPTGDPGPPGLMG 683
Query: 1679 -----AAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPP-APHDGDRKEL----PREQPL 1728
G P PG P ++ G PG+ + + G R E PR Q
Sbjct: 684 EKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG 743
Query: 1729 PPGPIGTERSQRTDRGTEP----------GPIRPSHRPGPPVQFGTSDKD 1768
P G G ++ T G P GP P+ PGP G KD
Sbjct: 744 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKD 793
Score = 60.8 bits (146), Expect = 1e-08
Identities = 160/658 (24%), Positives = 198/658 (30%), Gaps = 112/658 (17%)
Query: 105 PPESQPLPASQTPASNQ-PKRPPAAP--ENTPLVPS-----GVKSWAQASVTHGAHGDGG 156
PP + LP Q P PK PP P + P P G + G G G
Sbjct: 765 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 824
Query: 157 RASSLLSRFSREEFPTLQAAGDQD---KAAKERESAEQSSGPGPSLRPQNSTTWRDG--- 210
A R G+Q A KE + PGP P +DG
Sbjct: 825 AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD----PGPPGAPG-----KDGPAG 875
Query: 211 -----GGRG-PDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPP 264
G RG P GP K + G P G P+G P G P + PP P
Sbjct: 876 LRGFPGERGLPGTAGGPGLKGNEG--PSGPPGPAGSPGERGAAGSGGP-IGPPGRP---- 928
Query: 265 YGPQGPYRYPTPDGPSRFPRVAGPRGSGP------PMRLVEPVGRPSILKEDNLK-EFDQ 317
GPQGP P G P GP G P+ L P G P + ED K E
Sbjct: 929 -GPQGP---PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 984
Query: 318 LDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD-EEGAEGHRDSQSASGEERPPEADGK 376
Q+ G G H + + +D E GA G + A G+E +G
Sbjct: 985 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044
Query: 377 KGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPP 436
G P P ET + GP P P PP RGPAG G G GG
Sbjct: 1045 PGPIGLQGLPGPSGEKGETG-----DVGPMGP--PGPPGPRGPAGPNGADGPQGPPGGVG 1097
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496
P P ++ E E + R R + E
Sbjct: 1098 NLGP-PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES--------------------- 1135
Query: 497 FGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKEL--PAPPAPPPASAPT----------PE 543
G P EP P P P+ P P + P P PP P +
Sbjct: 1136 -GQP-----GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189
Query: 544 TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE 603
EP +P P PG GS + P P K GP P
Sbjct: 1190 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP- 1248
Query: 604 EVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
P P + +G +P + G P PP + + K ++ H
Sbjct: 1249 -AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG-PPGLPGLRGDAGAKGEKGHP 1306
Query: 664 WQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP------PKALYPGALGRPPPMP 715
G PP +P PQ P P A P G PP +P
Sbjct: 1307 GLIGLIG-------PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1357
Score = 52.4 bits (124), Expect = 5e-06
Identities = 98/418 (23%), Positives = 137/418 (32%), Gaps = 93/418 (22%)
Query: 96 KSSDASTAQPPESQPLPASQTPA----SNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151
++ D PP P + PA ++ P+ PP N L P G K S + G
Sbjct: 1062 ETGDVGPMGPPGP---PGPRGPAGPNGADGPQGPPGGVGN--LGPPGEKGEPGESGSPGI 1116
Query: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGG 211
G+ G R + E G + + + PGP P + +GG
Sbjct: 1117 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN-PGPVGFPGDPGPPGEGG 1175
Query: 212 GRGPDELEG----------PDSKLHHGHD----PRGGLQPSGPPQFPPYRGMMPPFMYPP 257
RG D +G P S G + P G P+G P +G P
Sbjct: 1176 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1235
Query: 258 YLPFPP---PYGPQGPYRYPTPDGPSRFPRVAGPRG-------SGPPMRLVEPVGRPSIL 307
+ P P GP GP P PDG P G +G +GPP PVG P +
Sbjct: 1236 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP----GPVGPPGL- 1290
Query: 308 KEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGE 367
G G + GA+G + G
Sbjct: 1291 ----------------PGLRG-----------------------DAGAKGEKGHPGLIGL 1311
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPP--HRGPAGNWGP 425
PP G+KG+ P E P + P P P LP P +G G GP
Sbjct: 1312 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1371
Query: 426 PGDYPDRG--GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEE 481
G ++G GPP P P + + + + + + RR + R MQE+
Sbjct: 1372 GGPKGEKGVQGPPGHPGPPGEVIQ-----------PLPIQMPKKTRRSVDGSRLMQED 1418
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 117 bits (294), Expect = 9e-26
Identities = 142/594 (23%), Positives = 197/594 (33%), Gaps = 76/594 (12%)
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP--PPHRGPAGNWGP 425
+ P K+ ++ P P T + + P E P P PK P P P P P
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 426 PGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAA 485
P P K PAP E K+ + + E A +E +E
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 486 CAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAP-----PAPPPASAP 540
++ K AP + P +AP+TP P + PAP PAP P
Sbjct: 384 TPKEPAPTTTK-SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 442
Query: 541 TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
P T P+EPA P + PT APT T+ + + P P K P
Sbjct: 443 AP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 601 PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660
PE+ P PTTP + T + P+ P K+ P ++
Sbjct: 502 TPEK-PAPTTPEELAPTTPEEPTPTTPEEPA-----PTTPKAAAPNTPKE---------- 545
Query: 661 QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD 720
AP TP P+P P + P PK P L P P P
Sbjct: 546 ----------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 721 PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
P+ + +P P P G P+ P+E + P PA +
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPT--TPKEPA--------PTTPKEPAPTTPK 645
Query: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
GT P K + TP +P P ++ A KG S T P P + P
Sbjct: 646 GTAPTTLK-----EPAPTTPKKPAP-----KELAPTTTKGPTSTTSDKPAPTTPKETAPT 695
Query: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP------PKEETAQLT 894
P+ AP P ++P P PP + +++ TP KEP P E T +L+
Sbjct: 696 TPKEPAPTTP------KKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELS 747
Query: 895 G---PEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAP 945
P+A + G P + T T R P AP
Sbjct: 748 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 801
Score = 117 bits (293), Expect = 1e-25
Identities = 149/561 (26%), Positives = 190/561 (33%), Gaps = 89/561 (15%)
Query: 505 KAEPAAP--PAAPSTPAPPPAVPKELPAPPA---PPPASAPTPETEPEEPAQAPPAQSTP 559
K+ P P PA +T P P PKE PAP P P + + T P+EPA P + P
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 311
Query: 560 TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP--PVPKVE 617
T APT +P EP + + P P + P PTTP P P
Sbjct: 312 TTPKEPAPT------------------TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Query: 618 PKGDGIGPTRQPPSQGL-GYPKYQKSLPPRFQRQQQEQLLKQ--QQQHQWQQHQQGSAPP 674
K P P+ P K P ++ K + SAP
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 675 TPVPPSPPQPVTLGAVPAPQAP----PPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYV 730
TP PSP T PAP P P PK P P P P P P
Sbjct: 414 TPKEPSP----TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469
Query: 731 DPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLA 790
P + P P P+ P++ + + P PA P P+
Sbjct: 470 TP-----KEPAPTTPKETAPT--TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-- 520
Query: 791 WVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPP 850
+ TP EP P T + AA K TP P P P P+ AP P
Sbjct: 521 ---EPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 575
Query: 851 ISRFP--LEEPGPRPLPWPPGSDEVAKIQTPPPKK---EPPKEETAQLTGPEAGRKPARG 905
P L+EP P P P E+A T P + P T + T P ++PA
Sbjct: 576 KGTAPTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634
Query: 906 VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIK----KPPPPTKV 961
P P+ + T T P P + ++ P E AP GP KP P T
Sbjct: 635 TPK-EPAPTTPKGTAPT-TLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPTTPK 690
Query: 962 EELPPKPLEQGDETPKPPKP--------------------DPLKITKGKLGGPKETPPNG 1001
E P P E TPK P P +P I K P E+ P
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPEL 746
Query: 1002 NLSPAPRLRRDYSYERVGPTS 1022
+ P P+ + E PT+
Sbjct: 747 SAEPTPKALENSPKEPGVPTT 767
Score = 116 bits (290), Expect = 3e-25
Identities = 156/649 (24%), Positives = 220/649 (33%), Gaps = 104/649 (16%)
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPE-----TEPGPPAPKPPLPPPHRGPAGN 422
+ P K+ S + PTP T + + P E T+ P PK P P + PA
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA-- 271
Query: 423 WGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEER 482
P + K PAP A +E
Sbjct: 272 ---PTTPKEPAPTTTKEPAPTTTKSA---------------------------PTTPKEP 301
Query: 483 RAACAEKLKRLDEKFGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKELPAPPAPPPASAPT 541
+K K AP + P P AP+T P P PKE PAP AP + T
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTT 360
Query: 542 PE----TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSS----TSSGSFEASPVEPQL 593
P+ T P+EPA + +PT APT +T+ T++ S +P EP
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420
Query: 594 PSKEGPEP--PEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQ 651
+ + P P P+E P PTTP P + T + P+ P K P ++
Sbjct: 421 TTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPA-----PTTTKKPAPTTPKEP 474
Query: 652 QEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP 711
K+ +AP TP +P P L + P P+ L P P
Sbjct: 475 APTTPKE------------TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Query: 712 PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-PGVHPSGLVPRERSDSGGSSSEPFD 770
P P P P+ P + P P+ P+E + + + P
Sbjct: 523 TPTTPEE--------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574
Query: 771 RHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
A + P PK ++ T EP T + A KG TP P
Sbjct: 575 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD--KPAPTTPKGTAPTTPKEPA 632
Query: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPP---KKEPPK 887
P P P+ AP L+EP P P P E+A T P + P
Sbjct: 633 PTTPKEPAPTTPKGTAP------TTLKEPAP-TTPKKPAPKELAPTTTKGPTSTTSDKPA 685
Query: 888 EETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--PEEP--- 942
T + T P ++PA P P++ + T T P P +S P +EP
Sbjct: 686 PTTPKETAPTTPKEPA---------PTTPKKPAPT-TPETPPPTTSEVSTPTTTKEPTTI 735
Query: 943 -GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGK 990
+P + P P +E P +P +TP KP+ K K
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Score = 112 bits (280), Expect = 4e-24
Identities = 144/623 (23%), Positives = 205/623 (32%), Gaps = 108/623 (17%)
Query: 436 PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDE 495
P PP + E K+++ E ++ + + + + EK D
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 496 KFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPA 555
AP ++ A+P P A +T P PKE PTP T P+EPA P
Sbjct: 188 ---APTSKVLAKPT-PKAETTTKGPALTTPKE------------PTPTT-PKEPASTTPK 230
Query: 556 QSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ-LPSKEGPEPPEEVPPPTTPPVP 614
+ TPT + +APT +P EP +K P P+E P TT
Sbjct: 231 EPTPTT-IKSAPT------------------TPKEPAPTTTKSAPTTPKEPAPTTTKEPA 271
Query: 615 KVEPKGDGIGPTRQP-PSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAP 673
PK T++P P+ P K P ++ K+ + P
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP---------TTP 322
Query: 674 PTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPR 733
P P +P +P PAP P P P A +P P P P P+
Sbjct: 323 KEPTPTTPKEPAPTTKEPAPTTPKEPA----PTAPKKPAPTTPKE--------PAPTTPK 370
Query: 734 LLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
+ P P P P + ++ EP AP + T P +P
Sbjct: 371 --EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP----APTTTKSAPTTPKEPSPTTTK 424
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
+ TP EP P T ++ A K TP P P P P+ AP P
Sbjct: 425 EPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482
Query: 854 FP-----LEEPGPRPL-------PWPPGSDEVAKI---QTPPPKKEPPKEETAQLTGPEA 898
P L P L P P +E+A + P E P T + P
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 899 GRKPARGVG------SGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPI 952
++PA + + P +E+ T G P + + P P+ P
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602
Query: 953 K----------KPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGN 1002
KP P T P P E TPK P P PK T P
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT----------PKGTAPTTL 652
Query: 1003 LSPAPRLRRDYSYERVGPTSCRG 1025
PAP + + + + PT+ +G
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTKG 675
Score = 84.7 bits (208), Expect = 9e-16
Identities = 142/632 (22%), Positives = 201/632 (31%), Gaps = 109/632 (17%)
Query: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809
P+ P+E + + + EP P ++ T P +P T TP EP P T+
Sbjct: 216 PTPTTPKEPAST--TPKEP----TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT- 267
Query: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPG 869
++ A K + T P P S P P+ AP P + P P P P
Sbjct: 268 -KEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPK 323
Query: 870 SDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPR 929
+ P P + P T + P A +KPA P +E T P
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA----------PTTPKEPAPTTPKEPA 373
Query: 930 PGSSRRGIP--PEEPGAPPRRAGPIK-KPPPPTKVEELPPKPLEQGDETPKPPKPDPLKI 986
P +++ P P+EP ++ P K P PT + P P E T K P P
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--- 430
Query: 987 TKGKLGGPKETPPNGNLSPAPRLRRD---YSYERVGPTSCRGRGRGEYFARGRGFRGTYG 1043
PKE P PAP ++ + + PT+ +
Sbjct: 431 -------PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK------------------- 464
Query: 1044 GRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEY--EEIPKRR 1101
P P P T ET + P++
Sbjct: 465 --------------------------KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 498
Query: 1102 RQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPP----PGAPPSPAPARFTARG 1157
E + T +LAP+ E PTP T + P P P P PAP T +
Sbjct: 499 APTTPEKPAPTTPEELAPTTPEEPTP---TTPEEPAPTTPKAAAPNTPKEPAPT--TPKE 553
Query: 1158 GRVFTPRG-VPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPS--KEPLKEKLI 1214
TP+ P+ P P PKKP L P+ KEP
Sbjct: 554 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613
Query: 1215 -PGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQE--RENAARGS 1271
P P +P + E G A K P K+ +E A +
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 1272 EGKPSLTLPASAPG---------PEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWE 1322
+G S T AP P+E T PAP P S ++ +E
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 733
Query: 1323 TASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354
T +S D ++ + P + +PK G P
Sbjct: 734 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 765
Score = 84.3 bits (207), Expect = 1e-15
Identities = 146/660 (22%), Positives = 213/660 (32%), Gaps = 91/660 (13%)
Query: 361 SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA 420
S + E P + P T K+A P T PAP P P P
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP- 439
Query: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE 480
K PAP E K+ + + + A +E +
Sbjct: 440 -----------------KKPAPTTPKEPAPTTPKEPAP--TTTKKPAPTTPKEPAPTTPK 480
Query: 481 ERRAACAEKLKRLDEKFGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKELPAPPAPPPASA 539
E +KL + AP K P P AP+TP P E PAP P A+
Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540
Query: 540 PTPE----TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPS 595
TP+ T P+EPA P + PT APT G T+ E +P P+ P+
Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-----EPAPTTPKKPA 595
Query: 596 KEGPEPPEEVPPPTT---PPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQ 652
+ P P +T P P PKG ++P P K P +
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPA------PTTPKEPAPTTPKGTA 648
Query: 653 EQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ---PVTLGAVPAPQAPPPP--PKALYPGA 707
LK+ AP TP P+P + T G P P PK P
Sbjct: 649 PTTLKE------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696
Query: 708 LGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSE 767
P P P P PP + P P +H S P E + S+E
Sbjct: 697 PKEPAPTTPKKPAPTTPETPPPTTSEV--STPTTTKEPTTIHKS---PDESTPE--LSAE 749
Query: 768 PFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRP-LTSPLRQAADEDDKGMRSETP 826
P + +E G P T TPA +P +T+ + E D +R+ TP
Sbjct: 750 PTPKALENSPKEPGVPT------------TKTPAATKPEMTTTAKDKTTERD--LRT-TP 794
Query: 827 PVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP 886
P + I+ + P K T PK
Sbjct: 795 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854
Query: 887 KE---ETAQLTGPEAGRKPARGVGSGGQGPPPPRRESR-----TETRWGPRPGSSRRGIP 938
K+ T + PE KP + P P++ ++ T T+ +P + R
Sbjct: 855 KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK---KPKTMPRVRK 911
Query: 939 PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETP 998
P+ P + + + P +++ E + + ++TP + ++ G ETP
Sbjct: 912 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 971
Score = 54.3 bits (129), Expect = 1e-06
Identities = 130/670 (19%), Positives = 225/670 (33%), Gaps = 67/670 (10%)
Query: 1083 TASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDK--EAPTPKEGTLTQVPLAPP 1140
T +T ++G E K + +++ +T DLAP+ K PTPK T T+ P
Sbjct: 158 TNKQTSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 212
Query: 1141 P----PGAPPSPA------PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAK 1190
P P P PA P T + TP+ + P + P +
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPT-TPKEPAPTTTKSAPTTPKEPAPTTTKEPA 271
Query: 1191 SLAPKKP-PTGPLPPSKEPLKEKLIPG-PLSPVARGGSNGGSNVGMEDGERPRRRRHGRA 1248
PK+P PT P+ P K P P P E +
Sbjct: 272 PTTPKEPAPTTTKEPA--PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 1249 QQQDKPPRFRRLKQERENAARGSEGKPSLTLPAS-APG-PEEALTTVTVAPAPRRAAAKS 1306
++ P + A + KP+ T P AP P+E T T P+P +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 1307 PDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGIS 1366
P + E T ++S+ T + P TPK P
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-------TTPKKP 442
Query: 1367 AMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPG 1426
A + ++++P + P P ++ ++ + P
Sbjct: 443 APTTPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 1427 RGDKRSWPSPKNRS-RPPEERPPGLPLPPPP--PSSSAVFRLDQVIHSNPAGIQQALAQL 1483
+K + +P+ + PEE P P P P P ++A + + P + A
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP----KEPAPT 557
Query: 1484 SSRQGSVTAPGGHPRHKPGLPQAPQG--------PSPRPPTRYEPQRVNSGLSSDP---H 1532
+ ++ + T P K P P+G P+P P + P+ + + +P
Sbjct: 558 TPKEPAPTTP------KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 1533 FEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGP 1592
++P P TP+ +A +P P P++P + P + P+ P
Sbjct: 612 CDKPAPT------TPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 663
Query: 1593 GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSG 1652
P+ E T T+ T ++ T +++ + EP P +P + T + +
Sbjct: 664 APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP--APTTPKKPAPTTPETPPPTT 720
Query: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPP 1712
++S + +S + + +AE PK S VP P + P
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
Query: 1713 APHDGDRKEL 1722
A ++L
Sbjct: 781 AKDKTTERDL 790
Score = 38.9 bits (89), Expect = 0.055
Identities = 69/355 (19%), Positives = 111/355 (31%), Gaps = 46/355 (12%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
P+P P P P P+ + + PA + ++ + T P
Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------PTTPKEPTPTTP 330
Query: 1494 GGH-PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
P K P P+ P+P P + P + P P TP++ A
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390
Query: 1553 VS----------PFPPKRRERP--PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRD 1600
+ P P + P P++P + P + P+ P P
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 1601 TGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGDS 1659
T P T++K + EP P +P E T + + + L+ +
Sbjct: 451 APTTPKEP------APTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTT 502
Query: 1660 QVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDR 1719
P + + P+ P ++P A P P+ P P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 555
Query: 1720 KELPREQPLPPGPIGTERSQRTDRGT------EPGPIRPSHRPGPPVQFGTSDKD 1768
P+E P P P E + T +GT EP P P +P P T+ K+
Sbjct: 556 PTTPKE-PAPTTP--KETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKE 606
Score = 38.5 bits (88), Expect = 0.072
Identities = 87/448 (19%), Positives = 144/448 (32%), Gaps = 44/448 (9%)
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRG----TEPGPIRPSHRPGPPVQFGTSDKDSDLRL 1773
++K +++P P P+ E D G T P H T+ K + R
Sbjct: 69 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 128
Query: 1774 VVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLY 1833
+ + KE + +V + V + S + + K + +S + L
Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 1834 P--EVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSAL 1891
P +V + + G A+ + P P TP +P P P+ +
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPT-----PTTPK------EPASTTPKEPTPTTI 237
Query: 1892 LSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLP 1951
S + +T A K PA P +P P P T+ P
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTT------KEP 286
Query: 1952 SPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLP 2011
+P+ S P P + P PA P + P P P P + P
Sbjct: 287 APTTTKSAPTTPKEPAPTTPK-KPA-----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340
Query: 2012 VGPALQPPSLAVRPPPAPATRVLPSPARP-FPASLGRAELHPVELKPFQDYQKLSSNLGG 2070
+ P+ PAP T P+P P PA E P K ++
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSA 396
Query: 2071 PGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIP-KPWERTG 2129
P +++ P + S + + +P+T T ++ +P + P P E
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAP 452
Query: 2130 PPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
P+E ++P KEP P+
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPK 480
Score = 33.5 bits (75), Expect = 2.3
Identities = 39/204 (19%), Positives = 61/204 (29%), Gaps = 7/204 (3%)
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHT 1616
P + E + P L + P + P+ P P T +
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGL 1676
T ++ ++ EP P +P E T + + + + P + +
Sbjct: 257 TTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 1677 KGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE----QPLPPGP 1732
K A PK P ++P P P P+ P P P+E P P P
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 1733 IGTERSQRTDRGTEPGPIRPSHRP 1756
T+ T EP P P
Sbjct: 375 TTTKEPSPT-TPKEPAPTTTKSAP 397
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 117 bits (294), Expect = 9e-26
Identities = 142/594 (23%), Positives = 197/594 (33%), Gaps = 76/594 (12%)
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP--PPHRGPAGNWGP 425
+ P K+ ++ P P T + + P E P P PK P P P P P
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 426 PGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAA 485
P P K PAP E K+ + + E A +E +E
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 486 CAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAP-----PAPPPASAP 540
++ K AP + P +AP+TP P + PAP PAP P
Sbjct: 425 TPKEPAPTTTK-SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP 483
Query: 541 TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE 600
P T P+EPA P + PT APT T+ + + P P K P
Sbjct: 484 AP-TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 601 PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ 660
PE+ P PTTP + T + P+ P K+ P ++
Sbjct: 543 TPEK-PAPTTPEELAPTTPEEPTPTTPEEPA-----PTTPKAAAPNTPKE---------- 586
Query: 661 QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD 720
AP TP P+P P + P PK P L P P P
Sbjct: 587 ----------PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 721 PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER 780
P+ + +P P P G P+ P+E + P PA +
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPT--TPKEPA--------PTTPKEPAPTTPK 686
Query: 781 GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG 840
GT P K + TP +P P ++ A KG S T P P + P
Sbjct: 687 GTAPTTLK-----EPAPTTPKKPAP-----KELAPTTTKGPTSTTSDKPAPTTPKETAPT 736
Query: 841 FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP------PKEETAQLT 894
P+ AP P ++P P PP + +++ TP KEP P E T +L+
Sbjct: 737 TPKEPAPTTP------KKPAPTTPETPPPT--TSEVSTPTTTKEPTTIHKSPDESTPELS 788
Query: 895 G---PEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAP 945
P+A + G P + T T R P AP
Sbjct: 789 AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 842
Score = 117 bits (293), Expect = 1e-25
Identities = 149/561 (26%), Positives = 190/561 (33%), Gaps = 89/561 (15%)
Query: 505 KAEPAAP--PAAPSTPAPPPAVPKELPAPPA---PPPASAPTPETEPEEPAQAPPAQSTP 559
K+ P P PA +T P P PKE PAP P P + + T P+EPA P + P
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKE-PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP 352
Query: 560 TPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTP--PVPKVE 617
T APT +P EP + + P P + P PTTP P P
Sbjct: 353 TTPKEPAPT------------------TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Query: 618 PKGDGIGPTRQPPSQGL-GYPKYQKSLPPRFQRQQQEQLLKQ--QQQHQWQQHQQGSAPP 674
K P P+ P K P ++ K + SAP
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 675 TPVPPSPPQPVTLGAVPAPQAP----PPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYV 730
TP PSP T PAP P P PK P P P P P P
Sbjct: 455 TPKEPSP----TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510
Query: 731 DPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLA 790
P + P P P+ P++ + + P PA P P+
Sbjct: 511 TP-----KEPAPTTPKETAPT--TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-- 561
Query: 791 WVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPP 850
+ TP EP P T + AA K TP P P P P+ AP P
Sbjct: 562 ---EPTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 616
Query: 851 ISRFP--LEEPGPRPLPWPPGSDEVAKIQTPPPKK---EPPKEETAQLTGPEAGRKPARG 905
P L+EP P P P E+A T P + P T + T P ++PA
Sbjct: 617 KGTAPTTLKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Query: 906 VGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIK----KPPPPTKV 961
P P+ + T T P P + ++ P E AP GP KP P T
Sbjct: 676 TPK-EPAPTTPKGTAPT-TLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPTTPK 731
Query: 962 EELPPKPLEQGDETPKPPKP--------------------DPLKITKGKLGGPKETPPNG 1001
E P P E TPK P P +P I K P E+ P
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPEL 787
Query: 1002 NLSPAPRLRRDYSYERVGPTS 1022
+ P P+ + E PT+
Sbjct: 788 SAEPTPKALENSPKEPGVPTT 808
Score = 116 bits (290), Expect = 3e-25
Identities = 156/649 (24%), Positives = 220/649 (33%), Gaps = 104/649 (16%)
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPE-----TEPGPPAPKPPLPPPHRGPAGN 422
+ P K+ S + PTP T + + P E T+ P PK P P + PA
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA-- 312
Query: 423 WGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEER 482
P + K PAP A +E
Sbjct: 313 ---PTTPKEPAPTTTKEPAPTTTKSA---------------------------PTTPKEP 342
Query: 483 RAACAEKLKRLDEKFGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKELPAPPAPPPASAPT 541
+K K AP + P P AP+T P P PKE PAP AP + T
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE-PAPTAPKKPAPTT 401
Query: 542 PE----TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSS----TSSGSFEASPVEPQL 593
P+ T P+EPA + +PT APT +T+ T++ S +P EP
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461
Query: 594 PSKEGPEP--PEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQ 651
+ + P P P+E P PTTP P + T + P+ P K P ++
Sbjct: 462 TTTKEPAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPA-----PTTTKKPAPTTPKEP 515
Query: 652 QEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP 711
K+ +AP TP +P P L + P P+ L P P
Sbjct: 516 APTTPKE------------TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Query: 712 PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-PGVHPSGLVPRERSDSGGSSSEPFD 770
P P P P+ P + P P+ P+E + + + P
Sbjct: 564 TPTTPEE--------PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615
Query: 771 RHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPP 830
A + P PK ++ T EP T + A KG TP P
Sbjct: 616 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD--KPAPTTPKGTAPTTPKEPA 673
Query: 831 PPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPP---KKEPPK 887
P P P+ AP L+EP P P P E+A T P + P
Sbjct: 674 PTTPKEPAPTTPKGTAP------TTLKEPAP-TTPKKPAPKELAPTTTKGPTSTTSDKPA 726
Query: 888 EETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIP--PEEP--- 942
T + T P ++PA P P++ + T T P P +S P +EP
Sbjct: 727 PTTPKETAPTTPKEPA---------PTTPKKPAPT-TPETPPPTTSEVSTPTTTKEPTTI 776
Query: 943 -GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGK 990
+P + P P +E P +P +TP KP+ K K
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Score = 112 bits (280), Expect = 4e-24
Identities = 144/623 (23%), Positives = 205/623 (32%), Gaps = 108/623 (17%)
Query: 436 PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDE 495
P PP + E K+++ E ++ + + + + EK D
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 496 KFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPA 555
AP ++ A+P P A +T P PKE PTP T P+EPA P
Sbjct: 229 ---APTSKVLAKPT-PKAETTTKGPALTTPKE------------PTPTT-PKEPASTTPK 271
Query: 556 QSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ-LPSKEGPEPPEEVPPPTTPPVP 614
+ TPT + +APT +P EP +K P P+E P TT
Sbjct: 272 EPTPTT-IKSAPT------------------TPKEPAPTTTKSAPTTPKEPAPTTTKEPA 312
Query: 615 KVEPKGDGIGPTRQP-PSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAP 673
PK T++P P+ P K P ++ K+ + P
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP---------TTP 363
Query: 674 PTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPR 733
P P +P +P PAP P P P A +P P P P P+
Sbjct: 364 KEPTPTTPKEPAPTTKEPAPTTPKEPA----PTAPKKPAPTTPKE--------PAPTTPK 411
Query: 734 LLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
+ P P P P + ++ EP AP + T P +P
Sbjct: 412 --EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP----APTTTKSAPTTPKEPSPTTTK 465
Query: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
+ TP EP P T ++ A K TP P P P P+ AP P
Sbjct: 466 EPAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523
Query: 854 FP-----LEEPGPRPL-------PWPPGSDEVAKI---QTPPPKKEPPKEETAQLTGPEA 898
P L P L P P +E+A + P E P T + P
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 899 GRKPARGVG------SGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPI 952
++PA + + P +E+ T G P + + P P+ P
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643
Query: 953 K----------KPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGN 1002
KP P T P P E TPK P P PK T P
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT----------PKGTAPTTL 693
Query: 1003 LSPAPRLRRDYSYERVGPTSCRG 1025
PAP + + + + PT+ +G
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTKG 716
Score = 84.7 bits (208), Expect = 9e-16
Identities = 142/632 (22%), Positives = 201/632 (31%), Gaps = 109/632 (17%)
Query: 750 PSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSP 809
P+ P+E + + + EP P ++ T P +P T TP EP P T+
Sbjct: 257 PTPTTPKEPAST--TPKEP----TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT- 308
Query: 810 LRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPG 869
++ A K + T P P S P P+ AP P + P P P P
Sbjct: 309 -KEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTP--KKPAPTTPKEPAPTTPK 364
Query: 870 SDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPR 929
+ P P + P T + P A +KPA P +E T P
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA----------PTTPKEPAPTTPKEPA 414
Query: 930 PGSSRRGIP--PEEPGAPPRRAGPIK-KPPPPTKVEELPPKPLEQGDETPKPPKPDPLKI 986
P +++ P P+EP ++ P K P PT + P P E T K P P
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT--- 471
Query: 987 TKGKLGGPKETPPNGNLSPAPRLRRD---YSYERVGPTSCRGRGRGEYFARGRGFRGTYG 1043
PKE P PAP ++ + + PT+ +
Sbjct: 472 -------PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK------------------- 505
Query: 1044 GRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEY--EEIPKRR 1101
P P P T ET + P++
Sbjct: 506 --------------------------KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL 539
Query: 1102 RQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPP----PGAPPSPAPARFTARG 1157
E + T +LAP+ E PTP T + P P P P PAP T +
Sbjct: 540 APTTPEKPAPTTPEELAPTTPEEPTP---TTPEEPAPTTPKAAAPNTPKEPAPT--TPKE 594
Query: 1158 GRVFTPRG-VPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPS--KEPLKEKLI 1214
TP+ P+ P P PKKP L P+ KEP
Sbjct: 595 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654
Query: 1215 -PGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQE--RENAARGS 1271
P P +P + E G A K P K+ +E A +
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 1272 EGKPSLTLPASAPG---------PEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWE 1322
+G S T AP P+E T PAP P S ++ +E
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 774
Query: 1323 TASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354
T +S D ++ + P + +PK G P
Sbjct: 775 TIHKSPDESTPELSAEPTPKALENSPKEPGVP 806
Score = 84.3 bits (207), Expect = 1e-15
Identities = 146/660 (22%), Positives = 213/660 (32%), Gaps = 91/660 (13%)
Query: 361 SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA 420
S + E P + P T K+A P T PAP P P P
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP- 480
Query: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE 480
K PAP E K+ + + + A +E +
Sbjct: 481 -----------------KKPAPTTPKEPAPTTPKEPAP--TTTKKPAPTTPKEPAPTTPK 521
Query: 481 ERRAACAEKLKRLDEKFGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKELPAPPAPPPASA 539
E +KL + AP K P P AP+TP P E PAP P A+
Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581
Query: 540 PTPE----TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPS 595
TP+ T P+EPA P + PT APT G T+ E +P P+ P+
Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-----EPAPTTPKKPA 636
Query: 596 KEGPEPPEEVPPPTT---PPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQ 652
+ P P +T P P PKG ++P P K P +
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAP-TTPKGTAPTTPKEPA------PTTPKEPAPTTPKGTA 689
Query: 653 EQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ---PVTLGAVPAPQAPPPP--PKALYPGA 707
LK+ AP TP P+P + T G P P PK P
Sbjct: 690 PTTLKE------------PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737
Query: 708 LGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSE 767
P P P P PP + P P +H S P E + S+E
Sbjct: 738 PKEPAPTTPKKPAPTTPETPPPTTSEV--STPTTTKEPTTIHKS---PDESTPE--LSAE 790
Query: 768 PFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRP-LTSPLRQAADEDDKGMRSETP 826
P + +E G P T TPA +P +T+ + E D +R+ TP
Sbjct: 791 PTPKALENSPKEPGVPT------------TKTPAATKPEMTTTAKDKTTERD--LRT-TP 835
Query: 827 PVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPP 886
P + I+ + P K T PK
Sbjct: 836 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895
Query: 887 KE---ETAQLTGPEAGRKPARGVGSGGQGPPPPRRESR-----TETRWGPRPGSSRRGIP 938
K+ T + PE KP + P P++ ++ T T+ +P + R
Sbjct: 896 KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK---KPKTMPRVRK 952
Query: 939 PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETP 998
P+ P + + + P +++ E + + ++TP + ++ G ETP
Sbjct: 953 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETP 1012
Score = 54.3 bits (129), Expect = 1e-06
Identities = 130/670 (19%), Positives = 225/670 (33%), Gaps = 67/670 (10%)
Query: 1083 TASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDK--EAPTPKEGTLTQVPLAPP 1140
T +T ++G E K + +++ +T DLAP+ K PTPK T T+ P
Sbjct: 199 TNKQTSTDGKE-----KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTT 253
Query: 1141 P----PGAPPSPA------PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAK 1190
P P P PA P T + TP+ + P + P +
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPT-TPKEPAPTTTKSAPTTPKEPAPTTTKEPA 312
Query: 1191 SLAPKKP-PTGPLPPSKEPLKEKLIPG-PLSPVARGGSNGGSNVGMEDGERPRRRRHGRA 1248
PK+P PT P+ P K P P P E +
Sbjct: 313 PTTPKEPAPTTTKEPA--PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 1249 QQQDKPPRFRRLKQERENAARGSEGKPSLTLPAS-APG-PEEALTTVTVAPAPRRAAAKS 1306
++ P + A + KP+ T P AP P+E T T P+P +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 1307 PDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGIS 1366
P + E T ++S+ T + P TPK P
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP-------TTPKKP 483
Query: 1367 AMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPG 1426
A + ++++P + P P ++ ++ + P
Sbjct: 484 APTTPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 1427 RGDKRSWPSPKNRS-RPPEERPPGLPLPPPP--PSSSAVFRLDQVIHSNPAGIQQALAQL 1483
+K + +P+ + PEE P P P P P ++A + + P + A
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP----KEPAPT 598
Query: 1484 SSRQGSVTAPGGHPRHKPGLPQAPQG--------PSPRPPTRYEPQRVNSGLSSDP---H 1532
+ ++ + T P K P P+G P+P P + P+ + + +P
Sbjct: 599 TPKEPAPTTP------KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 1533 FEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGP 1592
++P P TP+ +A +P P P++P + P + P+ P
Sbjct: 653 CDKPAPT------TPKGTAPTTPKEP--APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKP 704
Query: 1593 GPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSG 1652
P+ E T T+ T ++ T +++ + EP P +P + T + +
Sbjct: 705 APK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP--APTTPKKPAPTTPETPPPTT 761
Query: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPP 1712
++S + +S + + +AE PK S VP P + P
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
Query: 1713 APHDGDRKEL 1722
A ++L
Sbjct: 822 AKDKTTERDL 831
Score = 38.9 bits (89), Expect = 0.055
Identities = 69/355 (19%), Positives = 111/355 (31%), Gaps = 46/355 (12%)
Query: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP 1493
P+P P P P P+ + + PA + ++ + T P
Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-------PTTPKEPTPTTP 371
Query: 1494 GGH-PRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
P K P P+ P+P P + P + P P TP++ A
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431
Query: 1553 VS----------PFPPKRRERP--PRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRD 1600
+ P P + P P++P + P + P+ P P
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491
Query: 1601 TGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD-LSGDS 1659
T P T++K + EP P +P E T + + + L+ +
Sbjct: 492 APTTPKEP------APTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTT 543
Query: 1660 QVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDR 1719
P + + P+ P ++P A P P+ P P
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP-------NTPKEPAPTTPKEPA 596
Query: 1720 KELPREQPLPPGPIGTERSQRTDRGT------EPGPIRPSHRPGPPVQFGTSDKD 1768
P+E P P P E + T +GT EP P P +P P T+ K+
Sbjct: 597 PTTPKE-PAPTTP--KETAPTTPKGTAPTTLKEPAPTTPK-KPAPKELAPTTTKE 647
Score = 38.5 bits (88), Expect = 0.072
Identities = 87/448 (19%), Positives = 144/448 (32%), Gaps = 44/448 (9%)
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRG----TEPGPIRPSHRPGPPVQFGTSDKDSDLRL 1773
++K +++P P P+ E D G T P H T+ K + R
Sbjct: 110 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 169
Query: 1774 VVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLY 1833
+ + KE + +V + V + S + + K + +S + L
Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 1834 P--EVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSAL 1891
P +V + + G A+ + P P TP +P P P+ +
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPT-----PTTPK------EPASTTPKEPTPTTI 278
Query: 1892 LSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLP 1951
S + +T A K PA P +P P P T+ P
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTT------KEP 327
Query: 1952 SPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLP 2011
+P+ S P P + P PA P + P P P P + P
Sbjct: 328 APTTTKSAPTTPKEPAPTTPK-KPA-----PTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381
Query: 2012 VGPALQPPSLAVRPPPAPATRVLPSPARP-FPASLGRAELHPVELKPFQDYQKLSSNLGG 2070
+ P+ PAP T P+P P PA E P K ++
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE----PAPTTTKSA 437
Query: 2071 PGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIP-KPWERTG 2129
P +++ P + S + + +P+T T ++ +P + P P E
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAP 493
Query: 2130 PPPREGPSRRAEEPGSRGDKEPGLPPPR 2157
P+E ++P KEP P+
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPK 521
Score = 33.5 bits (75), Expect = 2.3
Identities = 39/204 (19%), Positives = 61/204 (29%), Gaps = 7/204 (3%)
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHT 1616
P + E + P L + P + P+ P P T +
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 1617 ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGL 1676
T ++ ++ EP P +P E T + + + + P + +
Sbjct: 298 TTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 1677 KGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPRE----QPLPPGP 1732
K A PK P ++P P P P+ P P P+E P P P
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 1733 IGTERSQRTDRGTEPGPIRPSHRP 1756
T+ T EP P P
Sbjct: 416 TTTKEPSPT-TPKEPAPTTTKSAP 438
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 116 bits (290), Expect = 3e-25
Identities = 328/1319 (24%), Positives = 428/1319 (32%), Gaps = 241/1319 (18%)
Query: 545 EPEEPAQAPPAQSTPTPGVAAAPTLVSGG-GSTSSTSSGSFEASPVEPQLPSKE-GPEPP 602
E E A A++ + A P + G G + G P P+ P+ GP
Sbjct: 356 EETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI 415
Query: 603 EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGL-GYPKYQKSLPPRFQRQQQEQ---LLKQ 658
+ P P P + P G+ P S G G P LP RF ++ + Q
Sbjct: 416 QGNPGPVGDPGERGPPGRAGL-----PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQ 470
Query: 659 QQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMN 718
+ Q Q Q A PP P+ P P P P G G P P
Sbjct: 471 EAQAQAILQQARLALR-----GPPGPMGYTGRPGPLGQPGSPGL--KGESGDLGPQGPRG 523
Query: 719 FDPRWMMIPPYVDPRLLQGRPPLDFY-----PPGVHPS----GL--VPRE---RSDSG-- 762
P+ + PP R +GR D PGV GL +P E R D+G
Sbjct: 524 --PQGLTGPPGKAGR--RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 579
Query: 763 ---GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDK 819
G E +R + RG P +G P P P P + D
Sbjct: 580 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP--KGPPGIPGP---PGVRGMDGPQG 634
Query: 820 GMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTP 879
S P P PP PG G PGP + P E GP+ P PG
Sbjct: 635 PKGSLGPQGEPGPPGQQGTPG--TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692
Query: 880 PPKKEPPKEETAQ-LTGPEA-----GRKPARGVGS-----GGQGPPPPRRESRTETRWGP 928
P K+ PP + Q +GP+ G + +GV G +G + G
Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 752
Query: 929 RPGSSRRGIP----PEEPGAPPRRAGPIKKPPPPTKVEE-----LPPKPLEQGDETPKPP 979
+ G+P + P P R GP P PP + E +P P G + PK
Sbjct: 753 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK-- 810
Query: 980 KPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGR-GF 1038
G LG P +G + GPT RG+ RG A G+ G
Sbjct: 811 ---------GSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQ-RGPRGATGKSGA 860
Query: 1039 RGTYGGRGRGARSREFRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASETRSEGSEYEE 1096
+GT GG G E RG G G G GP PP P G+ +
Sbjct: 861 KGTSGGDGPHGPPGE-------RGLPGPQGPNGFPGPKGPPGPPGK------------DG 901
Query: 1097 IPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV-----PLAPPPPGAPPSPAPA 1151
+P QRG E G + P P G + P P PPG P A
Sbjct: 902 LPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTA 960
Query: 1152 RFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPL 1209
G P G P + G G G P + PG + L + P+GP
Sbjct: 961 GKEGTKGDPGPP-GAPGKDGPAGLRGFPGERGLPG-TAGGPGLKGNEGPSGP-------- 1010
Query: 1210 KEKLIPGPL-SPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAA 1268
PGP SP RG + G +G GR Q P E
Sbjct: 1011 -----PGPAGSPGERGAAGSGGPIGPP----------GRPGPQGPPGAAGEKGVPGEKGP 1055
Query: 1269 RGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESS 1328
G G+ + P PGP A P ++ ++ D+ E
Sbjct: 1056 IGPTGRDGVQGPVGLPGP-----------------AGPPGVAGEDGDKG----EVGDPGQ 1094
Query: 1329 DFTSERRGDKEAP-PPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSS 1387
T +G+ P PP + P VG PG G PG +G + D R F+
Sbjct: 1095 KGTKGNKGEHGPPGPPGPIGP--VGQPGAAGADGEPGARG-PQGHFGAKG-DEGTRGFNG 1150
Query: 1388 QRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERP 1447
PG PGP G+ G +G G GP G GP + N + P+ P
Sbjct: 1151 P-PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP---------AGPNGADGPQGPP 1200
Query: 1448 PGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK--PGLPQ 1505
G+ PP + S GIQ + V P G K G P
Sbjct: 1201 GGVGNLGPPGEKG------EPGESGSPGIQG--------EPGVKGPRGERGEKGESGQPG 1246
Query: 1506 APQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM----VRGVGGTPRDSA-----GVSPF 1556
P P P+ PT + + N G P +PGP RG G D G
Sbjct: 1247 EPGPPGPKGPTGDDGPKGNPGPVGFPG--DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304
Query: 1557 PPKRRERPPRKPELLQEESLPPPHSSGFLGSK----------------PEGP-GPQAESR 1599
P E P P L + P S G G K P GP GP +
Sbjct: 1305 PGPTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG 1363
Query: 1600 DTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGV------ 1653
G L + + + ++ P + P L AG + + G+
Sbjct: 1364 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGP--PGLPGLRGDAGAKGEKGHPGLIGLIGP 1421
Query: 1654 ----DLSGDSQVSSGPCSQRSSPDGGLKGAAE-----GPPKRPGGSSPLNAVPCEGP--P 1702
GD + S + G+ GA+ GPP PG + P A GP P
Sbjct: 1422 PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGP 1481
Query: 1703 GSEPPRRPPPAPHDGDRKELPREQPLP-PGPIGTERSQRTDR-GTEPGPIRPSHRPGPP 1759
E + PP H G E+ QPLP P T RS R E I PG P
Sbjct: 1482 KGEKGVQGPPG-HPGPPGEV--IQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1537
Score = 108 bits (269), Expect = 7e-23
Identities = 331/1396 (23%), Positives = 433/1396 (31%), Gaps = 300/1396 (21%)
Query: 211 GGRGPDELEGP-DSKLHHGHDPR---------------GGLQPSGPPQFPPYRGMMPPFM 254
G G D EGP D +G D R G GP +G P +
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGE-PAVL 391
Query: 255 YPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGS-GPPMRLVEPVGRPSILKEDNLK 313
P L PP GP+GP P G P G G GPP R P
Sbjct: 392 EPGMLVEGPP-GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLP------------- 437
Query: 314 EFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEER---- 369
G GA + L F G D A +Q+ + R
Sbjct: 438 -----------GSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 486
Query: 370 -PPEADGKKGN-SPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPG 427
PP G G P +P +P + E G P+ P RGP G GPPG
Sbjct: 487 GPPGPMGYTGRPGPLGQPGSPGL---------KGESGDLGPQGP-----RGPQGLTGPPG 532
Query: 428 DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRM----QEERR 483
RG D + R L E+ R + ++ R
Sbjct: 533 KAGRRGRAGADGARGMPGDPGVKGDRGFDGLP-GLPGEKGHRGDTGAQGLPGPPGEDGER 591
Query: 484 AACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPE 543
E R G P + P P P PP + + P P + P E
Sbjct: 592 GDDGEIGPR-----GLPGESGPRGLLGPKGPPGIPGPPGV--RGMDGPQGPKGSLGPQGE 644
Query: 544 TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE 603
P P Q P P A P G S P P KEGP +
Sbjct: 645 PGPPGQQGTPGTQGLPGPQGAIGPH--GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702
Query: 604 EVPPPTTP--PVPKVEPKG----DGI-GPTRQPPSQGL-GYPKYQKSLPPRFQRQQQEQL 655
P+ P P+ P+G DGI G +G G+P ++ + + R E
Sbjct: 703 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG--EVG 760
Query: 656 LKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMP 715
+ + + +G PT P P G + P P P + G+LG P P
Sbjct: 761 VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG-FP 819
Query: 716 PMNFD-----------PRWMMIPP----YVDPRLLQGRPPLDFYPPGVHPSGLVPRERSD 760
+ + PR P PR G+ G P G P ER
Sbjct: 820 GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG-PPGERGL 878
Query: 761 SG--GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDD 818
G G + P + P + G P + VG P P + P A +
Sbjct: 879 PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 938
Query: 819 KGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQT 878
G R P PP PP E G PG +PGP P PG D A ++
Sbjct: 939 MGERGH--PGPPGPP--------GEQGLPGTAGKEGTKGDPGP---PGAPGKDGPAGLRG 985
Query: 879 PPPKKEPP----------KEETAQLTGPEAGRKPARGV-GSGGQGPPPPRRESRTETRWG 927
P ++ P E + GP AG RG GSGG PP R + G
Sbjct: 986 FPGERGLPGTAGGPGLKGNEGPSGPPGP-AGSPGERGAAGSGGPIGPPGRPGPQ-----G 1039
Query: 928 PRPGSSRRGIPPEE-PGAPPRR---AGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDP 983
P + +G+P E+ P P R GP+ P P P G++ K DP
Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP-------PGVAGEDGDKGEVGDP 1092
Query: 984 LKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARG----RGFR 1039
+ KG G E P G P + + + G RG +G + A+G RGF
Sbjct: 1093 GQ--KGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGP-QGHFGAKGDEGTRGFN 1149
Query: 1040 GTYGGRGRGARSREFRSYREFRGDDGRGGGTG-----GPNHPPAPRGRTA---------- 1084
G G G + G G G TG GP PP PRG
Sbjct: 1150 GPPGPIG----------LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1199
Query: 1085 ----------------SETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPK 1128
E+ S G + E K R E G + P + PT
Sbjct: 1200 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGD 1259
Query: 1129 EGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRG-RGGGRPPPQVCPGWSP 1187
+G P P G P P P GG PRG +G RG P Q PG
Sbjct: 1260 DGPKGN----PGPVGFPGDPGPP---GEGG----PRGQDGAKGDRGEDGEPGQ--PGSPG 1306
Query: 1188 PAKSLAPKKPPTGPLPPSKEPLKE--------KLIPGPLSPVARGGSNGGSNVGMEDGER 1239
P P P G P+ P E K PG + + G G + + G
Sbjct: 1307 PTGENGPPGP-LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD 1365
Query: 1240 PRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAP 1299
R G QQ +P A G G P P PG A
Sbjct: 1366 GLRGLPGSVGQQGRP------------GATGQAGPPGPVGPPGLPGLR--------GDAG 1405
Query: 1300 RRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGG 1359
+ P L + +GD+ P P G+PG G
Sbjct: 1406 AKGEKGHPGLIGLIGPPGEQG-------------EKGDRGLPGPQ-------GSPGQKGE 1445
Query: 1360 GAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGP 1419
+PG S G + PG+ PGP G G+ G++ G GGP
Sbjct: 1446 MGIPGAS----GPIGPGGP-----------PGL------PGPAGPKGAKGAT---GPGGP 1481
Query: 1420 GGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPS-----SSAVFRLDQVIHS--- 1471
G G P PP E LP+ P + S + + D+ I +
Sbjct: 1482 KGEKGV--------QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGA 1533
Query: 1472 --NPAGIQQALAQLSS 1485
+P G+++ L S
Sbjct: 1534 PGSPGGLEEIFGSLDS 1549
Score = 92.0 bits (227), Expect = 5e-18
Identities = 280/1149 (24%), Positives = 360/1149 (31%), Gaps = 238/1149 (20%)
Query: 211 GGRGPDELEG-PDSKLHHGHDPRGGLQPSGPPQFPPYRG---MMPPFMYPPYLPFPPPYG 266
G RG D L G P K H G GL GPP RG + P P G
Sbjct: 556 GDRGFDGLPGLPGEKGHRGDTGAQGLP--GPPGEDGERGDDGEIGPRGLPGESGPRGLLG 613
Query: 267 PQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGW 326
P+GP P P G GP+GS P P G+ L G
Sbjct: 614 PKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL--------PGPQGA 665
Query: 327 AGAHEEVDYTEK-----LKFSDEEDGRDSDEEGAEGHRDSQSASGEERP---PEADGKKG 378
G H E K + SD G +EG G + +Q SG + P P G KG
Sbjct: 666 IGPHGEKGPQGKPGLPGMPGSDGPPGHPG-KEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 724
Query: 379 ----------NSPNSEPPTP--------KTAWAETSRP-PETEPGPPAPK-------PPL 412
E P K E P E GP PK P
Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 784
Query: 413 PPPHRGPAGNWGPPG--DYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRR 470
PP G G G PG YP R GP P + + + S + R
Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK-----SGPRGE 839
Query: 471 REEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPA 530
R R Q R A K GA P PP P P P P
Sbjct: 840 RGPTGPRGQRGPRGATG--------KSGAKGTSGGDGPHGPPGERGLPGPQG--PNGFPG 889
Query: 531 PPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE 590
P PP P + P P Q G P +V G+ T P
Sbjct: 890 PKGPP--GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 947
Query: 591 PQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQ 650
P P ++G +P K +P G P + P+ G+P ++ LP
Sbjct: 948 PGPPGEQG------LPGTAGKEGTKGDPGPPG-APGKDGPAGLRGFPG-ERGLP------ 993
Query: 651 QQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ--------PVTLGAVPAPQAPPPPPKA 702
+ ++ S PP P SP + P+ P PQ PP A
Sbjct: 994 ------GTAGGPGLKGNEGPSGPPGPA-GSPGERGAAGSGGPIGPPGRPGPQG--PPGAA 1044
Query: 703 LYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
G G P+ P D +QG P+ P P V E D
Sbjct: 1045 GEKGVPGEKGPIGPTGRDG-------------VQG--PVGLPGPAGPPG--VAGEDGDK- 1086
Query: 763 GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMR 822
G +P + E G P + VG A P + D+G R
Sbjct: 1087 GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1146
Query: 823 SETPPVPPPPPYLASYPG----------FPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
PP P L PG G PGPP R P G PPG
Sbjct: 1147 GFNG--PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGG-- 1202
Query: 873 VAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG----VGSGGQ----GPPPPRRESRTET 924
V + P K EP + + + G E G K RG G GQ GPP P+ + +
Sbjct: 1203 VGNLGPPGEKGEPGESGSPGIQG-EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD- 1260
Query: 925 RWGPR-----------PGSSRRGIPPEEPGA-----------PPRRAGPIKKPPPPTKVE 962
GP+ PG G P + GA P GP + PP +
Sbjct: 1261 --GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1318
Query: 963 ELPP--KPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP 1020
+ P P +G + K K DP G +G P +T P G PA + GP
Sbjct: 1319 KRGPAGSPGSEGRQGGKGAKGDP-----GAIGAPGKTGPVGPAGPA---------GKPGP 1364
Query: 1021 TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR 1080
RG G+ G +GR G G+ G G P P
Sbjct: 1365 DGL------------RGLPGSVGQQGR-------------PGATGQAGPPGPVGPPGLPG 1399
Query: 1081 GRTASETRSEGSEYEEI-----PKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV 1135
R + + E I P + ++G P + +P K
Sbjct: 1400 LRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG---------LPGPQGSPGQKGEMGIPG 1450
Query: 1136 PLAPPPPGAPPS-PAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAP 1194
P PG PP P PA +G + T G P +G G + PP PG PP + + P
Sbjct: 1451 ASGPIGPGGPPGLPGPA--GPKGAKGATGPGGP--KGEKGVQGPPG-HPG--PPGEVIQP 1503
Query: 1195 -----KKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG--GSNVGMEDGERPRRRRHGR 1247
K + S+ +++ IP +P + GG GS + + RR G
Sbjct: 1504 LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTG- 1562
Query: 1248 AQQQDKPPR 1256
QD P R
Sbjct: 1563 --TQDSPAR 1569
Score = 88.2 bits (217), Expect = 8e-17
Identities = 311/1347 (23%), Positives = 415/1347 (30%), Gaps = 242/1347 (17%)
Query: 865 PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPP-------- 916
P P +E+ + PP +E E+T P A R A G GG PP
Sbjct: 294 PTPGEEEEILESSLLPPLEE---EQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGY 350
Query: 917 RRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQG---D 973
+ R ET GP A +G P K E+ P LE G +
Sbjct: 351 GDDYREETELGP------------ALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVE 398
Query: 974 ETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP--TSCRGRGRGEY 1031
P P P L G G P G P R S GP TS R
Sbjct: 399 GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--- 455
Query: 1032 FARGRGFRG-TYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASE-TRS 1089
F G G +G + A++ ++ RG G G TG P P G+ S +
Sbjct: 456 FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG----RPGPLGQPGSPGLKG 511
Query: 1090 EGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA 1149
E + R Q + + A +D P + + PG P
Sbjct: 512 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 571
Query: 1150 PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKE-- 1207
T G + P G RG G P+ PG S P L PK PP P PP
Sbjct: 572 HRGDTGAQG-LPGPPGEDGERG-DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM 629
Query: 1208 --PLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERE 1265
P K GP G G G + HG Q KP +
Sbjct: 630 DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP 689
Query: 1266 NAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETAS 1325
G EG P GP+ L P PR K D E+ E
Sbjct: 690 PGHPGKEGPPGTKGNQGPSGPQGPLG----YPGPR--GVKGVDGIRGLKGHKGEKGEDGF 743
Query: 1326 ESSDFTSERRGDK--------------EAP-----------PPVLL-------TPKAVGT 1353
+GD+ E P PP L+ P G
Sbjct: 744 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 803
Query: 1354 PGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSG 1413
PG G G + A+ LS +S G + GP G G SG+
Sbjct: 804 PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 863
Query: 1414 GGGGGPGGRTG----PGRGDKRSWPSPKNRSRPP-EERPPGLP------------LPPPP 1456
GG GP G G PG +P PK PP ++ PG P PP P
Sbjct: 864 SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923
Query: 1457 P-------SSSAVFRLDQVIHSNPAGI--QQALAQLSSRQGSVTAPGGHPRHKPGLPQAP 1507
P ++ + + H P G +Q L + ++G+ + PG P AP
Sbjct: 924 PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT--------KGDPGPPGAP 975
Query: 1508 QGPSPRPPTRYEPQRVNSGLSSDPHFE-EPGPM-VRGVGGTP--RDSAGV-SPFPPKRRE 1562
P + +R G + P + GP G G+P R +AG P P R
Sbjct: 976 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035
Query: 1563 RPPRKPELLQEESLP-------PPHSSGFLG----SKPEG-PGPQAESRDTGTEALTPHI 1610
P P E+ +P P G G P G PG E D G
Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095
Query: 1611 WNRLHTATSRKSYRPSSMEPWMEPLSPFED-------------VAGTEMSQSDSGVDLSG 1657
+ + P + P +P + D G E ++ +G
Sbjct: 1096 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1155
Query: 1658 DSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPP------ 1711
Q GP ++ GPP G + P A +GPPG PP
Sbjct: 1156 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1215
Query: 1712 ----------------PAPHDGDRKELPRE-QPLPPGPIGTERSQRTDRGTE--PGPIRP 1752
P G++ E + +P PPGP G D G + PGP+
Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG----PTGDDGPKGNPGPVGF 1271
Query: 1753 SHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQ 1812
PGPP + G +D GD D E P S P
Sbjct: 1272 PGDPGPPGEGGPRGQDG----AKGDR-----------------GEDGE--PGQPGSPGPT 1308
Query: 1813 SKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLH 1872
+N P G+R G AG S+ G ++ P + G PG
Sbjct: 1309 GEN-------GPPGPLGKR-------GPAGSPGSEGRQGGKGAKGDPGAIG-APGKTG-- 1351
Query: 1873 PYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPA 1932
P GPA P+ L+G L S Q G+ A G PP P
Sbjct: 1352 ---------PVGPAGPAGKPGPDGLRG--LPGSVGQQ---GRPGATGQAGPPGP--VGPP 1395
Query: 1933 FCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPG--GQSGFL-PSGAPAQQMLLPMVDSQLP 1989
P D + + P P + G G G P G+P Q+ + + + P
Sbjct: 1396 GLPGLRGDAG-AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1454
Query: 1990 VVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPP---PAPATRVLPSPARPFPASLG 2046
+ G P P PA P + GP V+ P P P V+ +P P +
Sbjct: 1455 -IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVI----QPLPIQMP 1509
Query: 2047 RAELHPVELKPFQDYQKLSSNLGGPGS 2073
+ V+ + G PGS
Sbjct: 1510 KKTRRSVDGSRLMQEDEAIPTGGAPGS 1536
Score = 77.8 bits (190), Expect = 1e-13
Identities = 242/1039 (23%), Positives = 301/1039 (28%), Gaps = 245/1039 (23%)
Query: 194 GPGPSLRPQNST-TWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPP 252
GP SL PQ G G L GP + P G P G P P G P
Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAI----GPHGEKGPQGKPGLPGMPGSDGP 689
Query: 253 FMYPPYLPFPP-------PYGPQGPYRYPTP------------------DGPSRFPR--- 284
+P PP P GPQGP YP P G FP
Sbjct: 690 PGHPGK-EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748
Query: 285 ------------VAGPRGS-GP--PMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGA 329
V G RG GP P P G P + E +L G+ G
Sbjct: 749 DIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG--PPGLMGEKGKLGVPGLPGYPGR 806
Query: 330 HE---EVDYTEKLKFSDEEDGRD-SDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEP 385
+ + S E+ R S + G G R G+ P A GK G S
Sbjct: 807 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 866
Query: 386 PTPKTAWAETSRP----------PETEPGPPAPK-------------------PPLPPPH 416
P E P P+ PGPP PP PP
Sbjct: 867 DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 926
Query: 417 RGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEER 476
GP G G G +RG P PP P E K+ + + R
Sbjct: 927 VGPQGAAGETGPMGERGHP--GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLR 984
Query: 477 RMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELP--APPAP 534
ER L G P + P+ PP +P A P P P
Sbjct: 985 GFPGER---------GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035
Query: 535 PPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
P P E P + P T GV L G + +P
Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095
Query: 595 SKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQ 654
+G + P P P IGP QP + G + F + E
Sbjct: 1096 GTKGNKGEHGPPGPPGP-----------IGPVGQPGAAGADGEPGARGPQGHFGAKGDEG 1144
Query: 655 L-----------LKQQQQHQWQQHQQGSAPP--TPVPPSPPQPVTLGAVPAPQAPP---- 697
L+ ++ + G P P PP P P PQ PP
Sbjct: 1145 TRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1204
Query: 698 ---PPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV 754
PP + PG G P +QG PGV
Sbjct: 1205 NLGPPGEKGEPGESGSPG----------------------IQGE-------PGVKG---- 1231
Query: 755 PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAA 814
PR G S +P + P G VG F P P P Q
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG--FPGDPGPPGE-GGPRGQDG 1288
Query: 815 DEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVA 874
+ D+G E P P ENG PGP R P PG G+
Sbjct: 1289 AKGDRGEDGEPGQPGSPGP-------TGENGPPGPLGKRGPAGSPGSEGRQGGKGA---- 1337
Query: 875 KIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSR 934
K +P TGP PA G GP R + + G RPG++
Sbjct: 1338 -------KGDPGAIGAPGKTGPVGPAGPA-----GKPGPDGLRGLPGSVGQQG-RPGATG 1384
Query: 935 RGIPP---EEPGAPPRR--AGPIKKPPPPTKVEELPPKPLEQGDETPKP-PKPDPLKITK 988
+ PP PG P R AG + P + + P P EQG++ + P P K
Sbjct: 1385 QAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP-PGEQGEKGDRGLPGPQGSPGQK 1443
Query: 989 GKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRG 1048
G++G P + P G P P L GP G +G G G G
Sbjct: 1444 GEMGIPGASGPIGPGGP-PGL--------PGPA---------------GPKGAKGATGPG 1479
Query: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKR--RRQRGS 1106
G G G G P HP P G + +P + ++ R S
Sbjct: 1480 -------------GPKGEKGVQGPPGHPGPP-----------GEVIQPLPIQMPKKTRRS 1515
Query: 1107 ETGSETHESDLAPSDKEAP 1125
GS + D A AP
Sbjct: 1516 VDGSRLMQEDEAIPTGGAP 1534
Score = 60.8 bits (146), Expect = 1e-08
Identities = 160/658 (24%), Positives = 198/658 (30%), Gaps = 112/658 (17%)
Query: 105 PPESQPLPASQTPASNQ-PKRPPAAP--ENTPLVPS-----GVKSWAQASVTHGAHGDGG 156
PP + LP Q P PK PP P + P P G + G G G
Sbjct: 872 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 931
Query: 157 RASSLLSRFSREEFPTLQAAGDQD---KAAKERESAEQSSGPGPSLRPQNSTTWRDG--- 210
A R G+Q A KE + PGP P +DG
Sbjct: 932 AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD----PGPPGAPG-----KDGPAG 982
Query: 211 -----GGRG-PDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPP 264
G RG P GP K + G P G P+G P G P + PP P
Sbjct: 983 LRGFPGERGLPGTAGGPGLKGNEG--PSGPPGPAGSPGERGAAGSGGP-IGPPGRP---- 1035
Query: 265 YGPQGPYRYPTPDGPSRFPRVAGPRGSGP------PMRLVEPVGRPSILKEDNLK-EFDQ 317
GPQGP P G P GP G P+ L P G P + ED K E
Sbjct: 1036 -GPQGP---PGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1091
Query: 318 LDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD-EEGAEGHRDSQSASGEERPPEADGK 376
Q+ G G H + + +D E GA G + A G+E +G
Sbjct: 1092 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1151
Query: 377 KGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPP 436
G P P ET + GP P P PP RGPAG G G GG
Sbjct: 1152 PGPIGLQGLPGPSGEKGETG-----DVGPMGP--PGPPGPRGPAGPNGADGPQGPPGGVG 1204
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEK 496
P P ++ E E + R R + E
Sbjct: 1205 NLGP-PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGES--------------------- 1242
Query: 497 FGAPDKRLKAEPAAP-PAAPSTPAPPPAVPKEL--PAPPAPPPASAPT----------PE 543
G P EP P P P+ P P + P P PP P +
Sbjct: 1243 -GQP-----GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1296
Query: 544 TEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPE 603
EP +P P PG GS + P P K GP P
Sbjct: 1297 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGP- 1355
Query: 604 EVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQ 663
P P + +G +P + G P PP + + K ++ H
Sbjct: 1356 -AGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG-PPGLPGLRGDAGAKGEKGHP 1413
Query: 664 WQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP------PKALYPGALGRPPPMP 715
G PP +P PQ P P A P G PP +P
Sbjct: 1414 GLIGLIG-------PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1464
Score = 52.4 bits (124), Expect = 5e-06
Identities = 98/418 (23%), Positives = 137/418 (32%), Gaps = 93/418 (22%)
Query: 96 KSSDASTAQPPESQPLPASQTPA----SNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151
++ D PP P + PA ++ P+ PP N L P G K S + G
Sbjct: 1169 ETGDVGPMGPPGP---PGPRGPAGPNGADGPQGPPGGVGN--LGPPGEKGEPGESGSPGI 1223
Query: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGG 211
G+ G R + E G + + + PGP P + +GG
Sbjct: 1224 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN-PGPVGFPGDPGPPGEGG 1282
Query: 212 GRGPDELEG----------PDSKLHHGHD----PRGGLQPSGPPQFPPYRGMMPPFMYPP 257
RG D +G P S G + P G P+G P +G P
Sbjct: 1283 PRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1342
Query: 258 YLPFPP---PYGPQGPYRYPTPDGPSRFPRVAGPRG-------SGPPMRLVEPVGRPSIL 307
+ P P GP GP P PDG P G +G +GPP PVG P +
Sbjct: 1343 AIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPP----GPVGPPGL- 1397
Query: 308 KEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGE 367
G G + GA+G + G
Sbjct: 1398 ----------------PGLRG-----------------------DAGAKGEKGHPGLIGL 1418
Query: 368 ERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPP--HRGPAGNWGP 425
PP G+KG+ P E P + P P P LP P +G G GP
Sbjct: 1419 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1478
Query: 426 PGDYPDRG--GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEE 481
G ++G GPP P P + + + + + + RR + R MQE+
Sbjct: 1479 GGPKGEKGVQGPPGHPGPPGEVIQ-----------PLPIQMPKKTRRSVDGSRLMQED 1525
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 115 bits (288), Expect = 5e-25
Identities = 171/663 (25%), Positives = 224/663 (33%), Gaps = 99/663 (14%)
Query: 362 QSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPL--PPPHRGP 419
++ +R + G + ++ P TP A A SR TE G P P P PP GP
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 420 AGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
+ ++ P P +R S S S A + R R
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP------STPAPPPAVPKELPAP-P 532
A ++ + + P + AAP P +TP+P A+ + P P
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 533 APPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQ 592
A P +S+ T + P APP+ S P P + P+ + S ++TS GS
Sbjct: 323 ATPHSSSLTCQLATPLPL-APPSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380
Query: 593 LPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQ 652
LPS P P PPP PP + P P PP L P P+
Sbjct: 381 LPSP--PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS------PQAPNALA 432
Query: 653 EQLLKQQQQHQWQQHQQGSAPPTPVPPSPP--QPVTLGAVPAPQAPP---PPPKALYPGA 707
LL+ +PP P SPP PV+ A P QAPP PP + P
Sbjct: 433 VHLLQ-------APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS- 484
Query: 708 LGRPPPMPPM--NFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSS 765
PP PPM + P PP P L +PP PP + L +
Sbjct: 485 ---PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ-APPALATPPLQALPSPPASFPG 540
Query: 766 SEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSET 825
PF A + TPP P P L +PL Q
Sbjct: 541 QAPFSPSASLPMSPLATPP---------------PQAPPVLAAPLLQ------------V 573
Query: 826 PPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPR-PLPWPPGSDEVAKIQTPPPKKE 884
PP PP P L + P P P +S GPR L PG PPP +
Sbjct: 574 PPSPPASPTLQA-PRRPPTPGPDTSVS-------GPRLTLALAPG-------PPPPPSRS 618
Query: 885 PPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGA 944
P ++ L+GP+ G S P R + GP G + PP+ A
Sbjct: 619 P----SSTLSGPDLA-----GHSSSATSTPEELRGYDS----GPE-GGAAASPPPDAELA 664
Query: 945 PPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLS 1004
A + P PP P PL T P D L G TP G L
Sbjct: 665 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSADGLCTIYETEGPESATPAPGALD 723
Query: 1005 PAP 1007
P P
Sbjct: 724 PGP 726
Score = 103 bits (258), Expect = 1e-21
Identities = 163/686 (23%), Positives = 222/686 (32%), Gaps = 115/686 (16%)
Query: 386 PTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYP--DRGG-------PP 436
P + T RPP G P P PP+ P G G G P +R G P
Sbjct: 17 PAARAPGLLTPRPP----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 437 CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAA----------- 485
P A R S S ERA + + RA+
Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 132
Query: 486 ----CAEKLKRLDEKFGAPDKR-LKAEPAAPPAAPSTPAPPPAVPKELPAP------PAP 534
AE+ + AP + L A + P+ P PA+ + A P P
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 535 PPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLP 594
P++ P P TE + + ++ + T AA S GG +S S +S P
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 595 SKEGPEPPEEVPPPTTPPVPKVEPKG------DGIGPTRQPPSQGLGYPKYQKSLP---P 645
++ GP P P PK PKG + P R+ + LG P L P
Sbjct: 253 ARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSP 309
Query: 646 RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYP 705
Q Q H Q + P PPSP P +L +P+P A PP
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT-- 367
Query: 706 GALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSS 765
+LG P +F P PP PL PP P+ +P
Sbjct: 368 -SLGSPTLQATHSFLPS----PPL---------SPLATPPPQAPPALALPP--------- 404
Query: 766 SEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSET 825
L+ +PP P L+ + T +P P L L QA +
Sbjct: 405 -----------LQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 826 PPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKK-- 883
P PP P + S P + AP P ++ PL+ P P PP S ++ TPPP+
Sbjct: 451 PFSPPASPPV-SPSATPPSQAP-PSLAAPPLQVP-----PSPPASPPMSPSATPPPQAPP 503
Query: 884 ----------EPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRP--- 930
+PP + L P P+ GQ P P P P
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563
Query: 931 ---GSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKIT 987
+ +PP P +P +A P P P L P PP P
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP---- 619
Query: 988 KGKLGGPKETPPNGNLSPAPRLRRDY 1013
L GP + + + P R Y
Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELRGY 645
Score = 88.6 bits (218), Expect = 6e-17
Identities = 196/839 (23%), Positives = 274/839 (32%), Gaps = 111/839 (13%)
Query: 1113 HESDLAPSDKEAPTPKE---GTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
++ D A + A TP G LT P P P P +PA R G V + + R
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-GRKPLAER 61
Query: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPS----KEPLKEKLIPGPL-SPVARG 1224
G GG P+ P P + + P P S + P + PGP+ SP
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 1225 GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAP 1284
G+ +G + R + + P R R + + + G PS PA A
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---PAMAR 178
Query: 1285 GPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPV 1344
A T V + P P +A P ++ + +E S
Sbjct: 179 RSRAAGTEVGL-PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---------------- 221
Query: 1345 LLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSK--RSFSSQR--PGMERQNRRPG 1400
P A P GG G+ + LS A LS RS S R P +P
Sbjct: 222 ---PAARRRPSAGG-----GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 1401 PGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKN--RSRPPEERPP---------- 1448
P G GP + PSP +S+ P P
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ 333
Query: 1449 -GLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAP 1507
PLP PPS SA L Q + S PA +Q ++ GS T H LP P
Sbjct: 334 LATPLPLAPPSPSAPPSL-QTLPSPPA---TPPSQATTSLGSPTLQATH----SFLPSPP 385
Query: 1508 QGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERP-PR 1566
P PP + P L + P +P S +SP + P
Sbjct: 386 LSPLATPPPQAPPALALPPLQAPP--------------SPPASPPLSPLATPSPQAPNAL 431
Query: 1567 KPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPS 1626
LLQ PPP P P + S ++A L S + P
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
Query: 1627 SMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKR 1686
S P +P +A + + +++ P SP G A P
Sbjct: 492 SPSATPPPQAP-PPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 1687 PGGSSPLNAVPCEGPPG-SEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGT 1745
SPL P + PP + P + PP+P + PR P PGP + R
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSGPRLTLAL 607
Query: 1746 EPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSA 1805
PGP P PP + +S + G L S E + R ++ P
Sbjct: 608 APGP------PPPPSRSPSS-------TLSGPDLAGHSSSATSTPEEL---RGYDSGPEG 651
Query: 1806 AASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAG---PSSSQISGGAMDSQLH-PNS 1861
A+A P + + C P S G P F G+ G P G+ D +
Sbjct: 652 GAAASP-PPDAELAACHPAAWSRGP-APPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 709
Query: 1862 GGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV 1920
G TP+ P L PGP+P ++ A G + + LG+LP G +
Sbjct: 710 EGPESATPA-------PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 761
Score = 85.1 bits (209), Expect = 7e-16
Identities = 176/739 (23%), Positives = 228/739 (30%), Gaps = 155/739 (20%)
Query: 1446 RPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKP--GL 1503
RPPG P PPPP + +A+ +V+ + A ++ LA+ + G T P PR P
Sbjct: 28 RPPGSPRPPPPVTPAAL----RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
Query: 1504 PQAPQGPSPRPPTRYEPQRVNSGLSSDP-HFEEPGPMVRGVGGTPRDSAGVSPFPPKRRE 1562
+ + P+ RPP +R ++ P PG R G T G E
Sbjct: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG---RASGTTRPGPLGQKGLRISAEE 140
Query: 1563 RPPR--KPELLQEESLPPPHSSGFLGSKPEGPGP--QAESRDTGTEA----LTPHIWNRL 1614
R E + +L G P P P SR GTE P R
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200
Query: 1615 HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDG 1674
T RKS +S EP SP A + G+ +SS S
Sbjct: 201 PTEGPRKSVSSASEHSTTEP-SP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 1675 GLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIG 1734
G +A G P+ P + P P +G PP+ PP + P PL P+
Sbjct: 256 G--PSARGTPRAP--AHPSQPKP-KGLQALRPPQVTPPR-----KDAAPALGPLSSSPLA 305
Query: 1735 TERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIP 1794
T P P PP T S LT + +P
Sbjct: 306 T-----------PSPSAALQSQAPPTLPATPHSSS---------------LTCQLATPLP 339
Query: 1795 VSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMD 1854
L + SA P + L S P PS + S G+
Sbjct: 340 -------LAPPSPSAPPSLQTLPSPPATP-------------------PSQATTSLGSPT 373
Query: 1855 SQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGK 1914
Q + F P P PL PP APP+ L
Sbjct: 374 LQA---THSFLPSPP------LSPLATPPPQAPPALALP--------------------- 403
Query: 1915 LPAGGVLYPPPSFLYSPAFCPSPLPDTSL---LQVRQDLPSPSDFYSTPLQPGGQSGFLP 1971
P PP S SP PSP +L L P PS P P P
Sbjct: 404 -PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 1972 SGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRP------ 2025
S P Q + L V P PPA PP+S P PP LA P
Sbjct: 463 SATPPSQAPPSLAAPPLQV-------PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 2026 ----PPAPAT---RVLPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPP 2078
PPA AT + LPSP FP + + + P + + + PP
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
Query: 2079 TGRSFSGLNS-RLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPS 2137
+ + L + R TP + V R+ L PP PPP PS
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSV-SGPRLTLALAPGPP--------------PPPSRSPS 620
Query: 2138 RRAEEPGSRGDKEPGLPPP 2156
P G P
Sbjct: 621 STLSGPDLAGHSSSATSTP 639
Score = 82.0 bits (201), Expect = 6e-15
Identities = 137/556 (24%), Positives = 184/556 (33%), Gaps = 83/556 (14%)
Query: 501 DKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPT 560
+KR KA+ A P+ AP P+ +P PPP + A +
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 561 PGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKG 620
G+ A S + + S+G+ +P S G P P T P P P G
Sbjct: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSP-G 118
Query: 621 DGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPS 680
G TR P LG + S R + + K+ ++ ++ PTP PS
Sbjct: 119 RASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGA--RRDTSGPTPGTPS 173
Query: 681 PPQPVTLGAV--------PAPQAPPPPP-----KAL-----------YPGALGRP----- 711
P A PAP A P PP K++ P A RP
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 712 ---PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGL-------VPRERSDS 761
P ++ + P P +G P +P P GL V R D+
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 762 ----GGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADED 817
G SS P +P+ + PP P + T A P PL P A
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL-TCQLATPLPLAPPSPSAPPS- 350
Query: 818 DKGMRSETPPVPP--PPPYLASYPGFPENGA-----PGPPISRFPLEEPGPRPLPWPPGS 870
+T P PP PP + G P A P PP+S PL P P+ P +
Sbjct: 351 -----LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPPPQ----APPA 399
Query: 871 DEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRP 930
+ +Q PP P P+A A + PPP + + P P
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSP-P 455
Query: 931 GSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPP-KPLEQGDETPKPPKPDPLKITKG 989
S PP P A P P PP +V PP P TP P P PL
Sbjct: 456 AS-----PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 990 KLGGPKETPPNGNLSP 1005
+L P P +P
Sbjct: 511 QLAKPPPQAPPALATP 526
Score = 74.3 bits (181), Expect = 1e-12
Identities = 201/870 (23%), Positives = 278/870 (31%), Gaps = 167/870 (19%)
Query: 865 PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPA--RGVGSGGQGPPP------P 916
P PPGS PPP P G GRKP R G GG P P
Sbjct: 27 PRPPGSPR------PPPPVTPAALRVLGAAGA-VGRKPLAERAGGIGGATIPESAPRAGP 79
Query: 917 RRESRTETRW-GPRPGSSRRG--IPPEEPGAP-----PRRAGPIKKPPP----------- 957
R + T +R RP +S RG PP + +P P RA +P P
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 958 ----PTKVEELPPKPL-----EQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008
K E P + + P P P P + + G + P S PR
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 1009 LRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGG 1068
+ + V S AR R G GG R A SR S R G
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAG--GGLQRPA-SRSLSSSATPLSSPARSG 256
Query: 1069 GTG-----GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPS--- 1120
+ P HP P+ + R ++ R+ G + PS
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPP-----QVTPPRKDAAPALGPLSSSPLATPSPSA 311
Query: 1121 --DKEAP-----TPKEGTLT-----QVPLAPPPPGAPPS--PAPARFTARGGRVFTPRGV 1166
+AP TP +LT +PLAPP P APPS P+ + T G
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371
Query: 1167 PSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGS 1226
P+ + P P + P +PP P+ PP LPP + P P PLSP+A
Sbjct: 372 PTLQATHSFLPSPPLSPLATPP-----PQAPPALALPPLQAPPSPPASP-PLSPLATPSP 425
Query: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286
+ + + + P PP Q + PS T P+ AP P
Sbjct: 426 QAPNALAVHLLQAP-------FSPPPSPP-----VQAPFSPPASPPVSPSATPPSQAP-P 472
Query: 1287 EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLL 1346
A + V P+P + SP A + + + PP L
Sbjct: 473 SLAAPPLQVPPSPPASPPMSP--------SATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524
Query: 1347 TP--KAVGTPGGGGGGAVPGISAMS-----------RGDLSQRAKDLSKRSFSSQRPGME 1393
TP +A+ +P G P + S + A L P ++
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 1394 RQNRRPGPGGKAGSSGS----SSGGGGGGPGGR------TGPG-RGDKRSWPSPKNRSRP 1442
R P PG SG + G P R +GP G S S R
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 644
Query: 1443 PEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPG 1502
+ P G PPP + ++ +PA + A + +G+ AP P
Sbjct: 645 YDSGPEGGAAASPPPDA-------ELAACHPAAWSRGPAPPLAFRGAPGAP------LPW 691
Query: 1503 LPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRE 1562
P G + T YE + S + P +PGP GG + +AG R
Sbjct: 692 PPATGPGSADGLCTIYETEGPESATPA-PGALDPGPSPGTSGG--KAAAGAGAGASSRSP 748
Query: 1563 RPPRKPEL------------LQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHI 1610
+ R EL L +L + G G GPG TG
Sbjct: 749 KQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG-------- 800
Query: 1611 WNRLHTATSRKSYRPSSMEPWMEPLSPFED 1640
+R + + + W E LSP ++
Sbjct: 801 -------GARAALSDAELGRWAELLSPLDE 823
Score = 68.2 bits (165), Expect = 8e-11
Identities = 161/639 (25%), Positives = 217/639 (33%), Gaps = 84/639 (13%)
Query: 1553 VSPFPP-KRRERPPRKPELLQEESL-------PPPHSSGFLGSK--PEGPGPQAESRDTG 1602
++P PP R PP P L+ P +G +G PE +R G
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 1603 TEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQ--SDSGVDLSGDSQ 1660
T + P A+ R P + P+S +GT G+ +S +
Sbjct: 85 TSSRNPA---SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
Query: 1661 VSSGPCSQ---RSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDG 1717
V+ G ++ RS+ G + GP PG SP A+ P PAP
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPT--PGTPSP--AMARRSRAAGTEVGLPRPAPS-- 195
Query: 1718 DRKELPREQPLPPGPIGTERSQRTDRGTEPGPI---RPSHRPGPPVQFGTSDKDSDLRLV 1774
R +P GP + S TEP P RPS G L+
Sbjct: 196 -----ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-------------LQRP 237
Query: 1775 VGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYP 1834
SL + +S + P +R P A ++P+ K L + P+ + + P
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQALR-PPQVTPPRKDAAP 294
Query: 1835 EVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYL-PPGPAPPSALLS 1893
+ S+ P ++ A+ SQ P P + SL + PL L PP P+ P +L +
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 1894 GLALKGQFLDFSTMQATELGK--LPAGGVLYPPPSFLYSPAFCPSP-LPDTSLLQVRQDL 1950
L + T LG L A P P SP P P P L Q
Sbjct: 354 ---LPSPPATPPSQATTSLGSPTLQATHSFLPSPPL--SPLATPPPQAPPALALPPLQAP 408
Query: 1951 PSPSDFYSTPLQP-GGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSL 2009
PSP S PL P S P+ + P P V P PPA PP+S
Sbjct: 409 PSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ----APFSPPASPPVSP 462
Query: 2010 LPVGPALQPPSLAVRP---PPAP------ATRVLPSPARPFPASLGRAEL--HPVELKPF 2058
P+ PPSLA P PP+P + P P P P + +L P + P
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522
Query: 2059 QDYQKLSSNLGGPGS-SRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDA 2117
L + P S P S S S L P V L Q P A
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPSPPA 579
Query: 2118 LRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156
+ P PP GP P PG PPP
Sbjct: 580 SPTLQAPRR----PPTPGPDTSVSGPRLTLALAPGPPPP 614
Score = 67.4 bits (163), Expect = 1e-10
Identities = 166/744 (22%), Positives = 232/744 (31%), Gaps = 166/744 (22%)
Query: 55 RMPPPANLPSLK----AENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQP 110
R PPP +L+ A G P L + G + +S P++ +A S
Sbjct: 34 RPPPPVTPAALRVLGAAGAVGRKP---LAERAGGIGGATIPESAPRAGPTRSAGT--SSR 88
Query: 111 LPASQTPASNQPKRPPAAPENT-----------------PLVPSGVKSWAQASVTHGAHG 153
PAS+ PAS + +R P A + PL G++ A+ +V G
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 154 DGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSS--GPGPSLRP---------- 201
+ + S+L + R+ A + R + + P PS RP
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 202 -----QNSTT----------WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPY 246
++STT GG + P S R G G P+ P +
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 247 ---------RGMMPPFMYPPYLPFPPPYGP--QGPYRYPTP------DGPSRFPRVAGPR 289
+ + PP + PP P GP P P+P P P A P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP--ATPH 326
Query: 290 GSGPPMRLVE--PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347
S +L P+ PS +L+ A T L
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPS---------PPATPPSQATTSL-------- 369
Query: 348 RDSDEEGAEGHRDSQSASGEERP-PEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP 406
+ S S P P+A P PP+P A P P P
Sbjct: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP---ASPPLSPLATPSPQ 426
Query: 407 APK---------PPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSS 457
AP P PPP + PP P P PP+ A + S
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQAPPSLAAPPLQVPPS 484
Query: 458 SEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPST 517
S + + A + AP +L A+P PP AP
Sbjct: 485 PPASPPM-------------------SPSATPPPQAPPPLAAPPLQL-AKP--PPQAPPA 522
Query: 518 PAPPPAVPKELPAPPAPPPASAP-TPETE-PEEPAQAPPAQSTPTPGVAAAPTLVSGGGS 575
A PP + LP+PPA P AP +P P P PP Q+ P V AAP L
Sbjct: 523 LATPPL--QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP---VLAAPLL------ 571
Query: 576 TSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVE---PKGDGIGPTRQPPSQ 632
+ P P P+ + P P P T+ P++ G P+R P S
Sbjct: 572 ---------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622
Query: 633 GLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPA 692
G P ++ + +G A +P PP PA
Sbjct: 623 LSG---------PDLAGHSSSATSTPEELRGYDSGPEGGAAASP----PPDAELAACHPA 669
Query: 693 PQAPPPPPKALYPGALGRPPPMPP 716
+ P P + GA G P P PP
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPP 693
Score = 50.8 bits (120), Expect = 1e-05
Identities = 94/362 (25%), Positives = 115/362 (31%), Gaps = 54/362 (14%)
Query: 103 AQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLL 162
A PP P PA P P PPA+P +PL ++ A H L
Sbjct: 390 ATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVH----------LLQ 437
Query: 163 SRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRP---QNSTTWRDGGGRGPDELE 219
+ FS P +QA + SA S PSL Q + P
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Query: 220 GPDSKLHHGHDPRGGLQPSGPPQFPPYRGM-------MPPFMYPPYLPFPPPYG-PQGPY 271
P + P +P PPQ PP PP +P PF P P P
Sbjct: 498 PPQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 272 RYPTPDGPSRFPRVAGPRGSGPPMRLVEPV----GRPSILKEDNLKEFDQLDQENDDGWA 327
P P P P +A P PP P RP D +L G
Sbjct: 556 ATPPPQAP---PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 328 GAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPT 387
S G D GH S +++ EE G +G + S PP
Sbjct: 613 PPPSRSP-------SSTLSGPD-----LAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
Query: 388 PK------TAWAETSRPPETEPGPPAPKPPLP-PPHRGPAGNWGPPGDYPDRGGPPCKPP 440
+ AW+ PP G AP PLP PP GP G Y + GP P
Sbjct: 661 AELAACHPAAWSRGPAPPLAFRG--APGAPLPWPPATGPGSADGLCTIY-ETEGPESATP 717
Query: 441 AP 442
AP
Sbjct: 718 AP 719
Score = 42.7 bits (99), Expect = 0.004
Identities = 63/269 (23%), Positives = 84/269 (31%), Gaps = 27/269 (10%)
Query: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
PP PSL A P+ P + P ++ P Q PA T
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525
Query: 117 PASNQPKRPPAA-PENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQA 175
P PPA+ P P PS + + A L S PTLQA
Sbjct: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 176 A------GDQDKAAKERESAEQSSGPGP--SLRPQNSTTWRDGGGRGPDELEGPDSKLHH 227
G + R + + GP P S P ++ + D G P+ +
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Query: 228 GHDPRGGLQPSGPPQFPP--------YRGMMPPFMY----PPYLPFPPPYGPQGPYRYPT 275
P GG S PP RG PP + LP+PP GP +
Sbjct: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP------GS 699
Query: 276 PDGPSRFPRVAGPRGSGPPMRLVEPVGRP 304
DG GP + P ++P P
Sbjct: 700 ADGLCTIYETEGPESATPAPGALDPGPSP 728
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 115 bits (288), Expect = 5e-25
Identities = 363/1539 (23%), Positives = 485/1539 (31%), Gaps = 354/1539 (23%)
Query: 52 IARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPE---- 107
+A + P P K + KG K G G K + K+ + T+ PP
Sbjct: 233 VAPQGEPETPRPRRKGKGKGR--------KKGRGRKGKGRK---KNKEIWTSSPPPDSAE 281
Query: 108 ---SQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSR 164
S +P ++TPA N P P TPLV + ++VT G + S L
Sbjct: 282 NQTSTDIPKTETPAPNLPPTP------TPLVVT-------STVTTGLNATILERS--LDP 326
Query: 165 FSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQ---NSTTWRDGGGRGPDELEGP 221
S E TL+ KAA+E E + S+ GP R + T ++ G G +G
Sbjct: 327 DSGTELGTLET-----KAAREDEEGDDST-MGPDFRAAEYPSRTQFQIFPGAGEKGAKGE 380
Query: 222 DSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSR 281
+ + G Q GPP P +G++ P P FP GP GP P G
Sbjct: 381 PAVIEKGQ------QFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLP---GIPG 431
Query: 282 FPRVAGPRGS--------------GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWA 327
+ GP G+ GPP+ + + ++L++ L G
Sbjct: 432 IDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQ-AVLQQTQL---SMKGPPGPVGLT 487
Query: 328 GAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADGKKGN-SPNSEPP 386
G V EEGAEG + + G PP GK G +
Sbjct: 488 GRPGPVGLPGHPGL--------KGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARG 539
Query: 387 TPKTAWAETSRPPETEPGPPAPK----------PPLPPPHRGPAGNWGPPGDYPDRGGP- 435
P + R + PG P K P PP G G GPPG G P
Sbjct: 540 LPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599
Query: 436 ------PCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEK 489
P P P + + I A E ++ ++
Sbjct: 600 PRGLLGPRGSPGPTG---------RPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG 650
Query: 490 LKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEP 549
L G P ++ PP P P P + P P PT E+
Sbjct: 651 LPGPQGLIGTPGEK------GPPGNPGIPGLPGS-----DGPLGHPGHEGPT----GEKG 695
Query: 550 AQAPPAQSTPTPGVAAAPTLVSG-------GGSTSSTSSGSF------------EASPVE 590
AQ PP + P PG P V G G F + P
Sbjct: 696 AQGPPGSAGP-PGY-PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGA 753
Query: 591 PQLPSKEGPEPP--------EEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKS 642
P ++GPE P EE PP + K+ G P R P +G+P
Sbjct: 754 PGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP---GP 810
Query: 643 LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKA 702
L P ++ + + Q + ++ GS P + QP G V AP P +
Sbjct: 811 LGPIGEKGKSGK--TGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEK 868
Query: 703 LYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSG 762
PG G PP P P+ PPG
Sbjct: 869 GLPGLQG-PPGFP----GPKG---------------------PPG-------------HQ 889
Query: 763 GSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMR 822
G P G P +L + G P P + P + + G R
Sbjct: 890 GKDGRP------------GHPGQRGELGFQGQ---TGPPGPAGVLGPQGKTGEVGPLGER 934
Query: 823 SETPPVPPPPPYLASYPGFP-ENGAPGPPISRFPLEEPGP---RPLPWPPGSDEVAKIQT 878
PP PP PP PG GA G PL + GP R P P G
Sbjct: 935 G--PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG 992
Query: 879 PPPKKEPPKEETAQLTGPEAG-RKPARGVG----SGGQGPPPPRRESRTETRWGPRPGSS 933
K PP A + E G PA G+G SG +GP P + + GP +
Sbjct: 993 LKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG 1052
Query: 934 RRGIP-PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDE-TPKPPKPDPLKITKGKL 991
+ GIP P P PP AGP E+GD+ P K KG
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSG----------------EEGDKGDVGAPGHKGSKGDKGDA 1096
Query: 992 GGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARS 1051
G P + G D + R GP G+ + RGF G G G
Sbjct: 1097 GPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGV---RGFVGVIGPPG----- 1148
Query: 1052 REFRSYREFRGDDGRGGGTG--GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS--E 1107
+ G+ G G G GP+ P PRG T SEG+ +P Q G+ E
Sbjct: 1149 --LQGLPGPPGEKGEVGDVGSMGPHGAPGPRG-PQGPTGSEGT--PGLPGGVGQPGAVGE 1203
Query: 1108 TGSETHESDLAPSDKEA-PTPKEGTLTQVPLAPPPPGAPPSP--APARFTARGGRVFTPR 1164
G D P P PK + P PP P A+G P
Sbjct: 1204 KGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGS--VGPT 1261
Query: 1165 GVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP---TGPLPPSKEPLKEKLIPGPLSPV 1221
G+P G G PG S S K P GP PP E PGP P
Sbjct: 1262 GLPGDLGPPGD-------PGVSGIDGSPGEKGDPGDVGGPGPPGAS--GEPGAPGP--PG 1310
Query: 1222 ARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPA 1281
RG S G R R G + +P G +G P T P
Sbjct: 1311 KRGPS----------GHMGREGREGEKGAKGEP---------------GPDGPPGRTGPM 1345
Query: 1282 SAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP 1341
A GP + + P
Sbjct: 1346 GARGPPGRVGPEGLRGIP-------------------------------------GPVGE 1368
Query: 1342 PPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD--------LSKRSFSSQR--PG 1391
P +L P +G PG G +PG+ +GD + + + + ++ G
Sbjct: 1369 PGLLGAPGQMGPPGPLGPSGLPGL----KGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424
Query: 1392 MERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLP 1451
+ PGP G G G G GP G GP G K S SP + + P G P
Sbjct: 1425 LPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGP-LGQKGSKGSPGSMGPRGDTGPAGPP 1483
Query: 1452 LPPPPPSSSAVFRLDQVIHSNP-----AGIQQALAQLSS 1485
PP P+ R + P G+++ LA L+S
Sbjct: 1484 GPPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTS 1522
Score = 110 bits (276), Expect = 1e-23
Identities = 357/1539 (23%), Positives = 471/1539 (30%), Gaps = 381/1539 (24%)
Query: 466 RARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVP 525
R RR+ + + R+ R+ +K K + PD AE P T P P +P
Sbjct: 243 RPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDS---AENQTSTDIPKTETPAPNLP 299
Query: 526 KELPAPPAPPP--------------------------------ASAPTPETEPEEPAQAP 553
P P P A + E ++ P
Sbjct: 300 ------PTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGP 353
Query: 554 PAQSTPTPGVAAAPTLVSGG-----GSTSSTSSGS-FEASPVEPQ---LPSKEGPEPPEE 604
++ P G G + G FE P P + GP P
Sbjct: 354 DFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPG 413
Query: 605 VPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQ------KSLPPRFQRQQQEQLLKQ 658
P PP P P GI R PP + P +Q K P FQ+ Q + +L+Q
Sbjct: 414 FPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMP-FQFAGGSFKGPPVSFQQAQAQAVLQQ 472
Query: 659 QQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMN 718
Q PP PV L P P P +PG G P
Sbjct: 473 TQLSM---------------KGPPGPVGLTGRPGPVGLPG-----HPGLKGEEGAEGPQG 512
Query: 719 FDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLR 778
PR LQG P P + R + G+ P D
Sbjct: 513 -------------PRGLQG--------PHGPPGRVGKMGRPGADGARGLPGDTGPKG--- 548
Query: 779 ERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASY 838
+RG F P P +KG R + V P P
Sbjct: 549 DRG--------------FDGLPGLP-------------GEKGQRGDFGHVGQPGP----- 576
Query: 839 PGFP-ENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPE 897
PG E GA GPP EPGPR L P GS P P P +TG +
Sbjct: 577 PGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGS--------PGPTGRP------GVTGID 622
Query: 898 AGRKPARGVGSGGQGPPPPRRESRTETRWGPRP----GSSRRGIPPEEPGAP--PRRAGP 951
VG G+ P PP ++ ++ P P G+ PP PG P P GP
Sbjct: 623 GAPGAKGNVGPPGE-PGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGP 681
Query: 952 IKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
+ P G E P KG G P P G P
Sbjct: 682 LGHP----------------GHEGPTG--------EKGAQGPPGSAGPPGYPGP------ 711
Query: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRG----RGARSREFRSYREFRGDDGRG 1067
RG +GT G RG +G + + + F+GD G
Sbjct: 712 ------------------------RGVKGTSGNRGLQGEKGEKGED--GFPGFKGDVGLK 745
Query: 1068 GGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTP 1127
G G P P PRG E+ P+ + + + G E P
Sbjct: 746 GDQGKPG-APGPRG-------------EDGPEGPKGQAGQAGEE------GPPGSAGEKG 785
Query: 1128 KEGTLTQVPLAPPPPGAP--------PSP-APARFTARGGRVFTP-----RGVPSRRGRG 1173
K G VP P PG P P P P + G+ P RG P RG
Sbjct: 786 KLG----VPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGER 841
Query: 1174 G-----GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNG 1228
G G+P P+ G + AP P LP + P PGP P G +G
Sbjct: 842 GQPGATGQPGPKGDVG-----QDGAPGIPGEKGLPGLQGP---PGFPGPKGPPGHQGKDG 893
Query: 1229 GSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEE 1288
G +R G Q P L + + G G+ P PG E+
Sbjct: 894 ------RPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPG-EQ 946
Query: 1289 ALTTVTVAPAPRRAAAKSPDLSNQN-SDQANEEWETASESSDFTSERRGDKEAPPPVLL- 1346
L + + L + + + +GDK P PV
Sbjct: 947 GLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGAN 1006
Query: 1347 -TPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKA 1405
+P G G GG +PG S S G + K S+ PG ++ PGP G
Sbjct: 1007 GSPGERGPLGPAGGIGLPGQSG-SEGPVGPAGKKGSRGERGP--PGPTGKDGIPGPLGPL 1063
Query: 1406 GSSGSSSGGGGGGPGGRTG-PG----RGDKRSWPSPKNRSRPPEERPPGLPLPP------ 1454
G G++ G G G G PG +GDK P +P P G P PP
Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPP---GQPGIRGPAGHPGPPGADGAQ 1120
Query: 1455 ----PP-----PSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQ 1505
PP V VI P G+ Q L +G V G H P+
Sbjct: 1121 GRRGPPGLFGQKGDDGVRGFVGVI--GPPGL-QGLPGPPGEKGEVGDVGSMGPHGAPGPR 1177
Query: 1506 APQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP 1565
PQGP+ T P V +PG + G G D+ P PP P
Sbjct: 1178 GPQGPTGSEGTPGLPGGVG----------QPGAV--GEKGERGDAG--DPGPPGAPGIPG 1223
Query: 1566 RKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRP 1625
K ++ ++ P ++G G K GP E G+ T P
Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKK----GPPGEDGAKGSVGPTG---------------LP 1264
Query: 1626 SSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK 1685
+ P +P SG+D S + G P + A GPP
Sbjct: 1265 GDLGPPGDP--------------GVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPG 1310
Query: 1686 RPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGT 1745
+ G S + EG G+ + P P + P PPG +G E +
Sbjct: 1311 KRGPSGHMGREGREGEKGA----KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPV 1366
Query: 1746 -EPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDS-LKAEKELTASVTEAIPVSRDWELLP 1803
EPG + + GPP G S L + GD+ K EK + L+
Sbjct: 1367 GEPGLLGAPGQMGPPGPLG----PSGLPGLKGDTGPKGEKGHIGLI----------GLIG 1412
Query: 1804 SAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGG 1863
+ E + L P P P G GP G S+ P S G
Sbjct: 1413 PPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMG 1472
Query: 1864 FRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFL 1902
R T PPGP A L GL + +F+
Sbjct: 1473 PRGDTGPAG---------PPGPPGAPAELHGLRRRRRFV 1502
Score = 48.1 bits (113), Expect = 9e-05
Identities = 143/629 (22%), Positives = 192/629 (30%), Gaps = 108/629 (17%)
Query: 1180 QVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGER 1239
Q C + P +LAP + P EP P P R G G G G +
Sbjct: 215 QACERYLPDCDNLAP----AATVAPQGEPET----PRP----RRKGKGKGRKKGR--GRK 260
Query: 1240 PRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAP 1299
+ R+ + PP EN K P P P + T TV
Sbjct: 261 GKGRKKNKEIWTSSPP-----PDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGL 315
Query: 1300 RRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGG 1359
+ + ++ E + A E + G + PG G
Sbjct: 316 NATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEK 375
Query: 1360 GAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGP 1419
GA + + +G + PG GP G G G G GP
Sbjct: 376 GAKGEPAVIEKGQQFEGP------------PGAPGPQGVVGPSGPPGPPGFPGDPGPPGP 423
Query: 1420 GGRTG-PGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQ 1478
G G PG R PPG + P + F+ P QQ
Sbjct: 424 AGLPGIPGIDGIRG--------------PPGTVIMMPFQFAGGSFK------GPPVSFQQ 463
Query: 1479 ALAQLSSRQGSVTAPG--------------GHPRHKPGLP-----QAPQGPSPRPPTRYE 1519
A AQ +Q ++ G G P H PGL + PQGP
Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGH-PGLKGEEGAEGPQGPRGLQGPHGP 522
Query: 1520 PQRVNSGLSSDPHFEEPGPM-VRGVGGT--PRDSAGVSPFPPKRRERPPRKPELLQEESL 1576
P RV PG RG+ G P+ G P E+ R +
Sbjct: 523 PGRVGK-------MGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRG-DFGHVGQP 574
Query: 1577 PPPHSSGFLGSKPEGPGPQAESRDTGTEAL-----TPHIWNRLH-TATSRKSYRPSSMEP 1630
PP G G++ PGP ++ + G L +P R T ++ P
Sbjct: 575 GPPGEDGERGAEGP-PGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGP 633
Query: 1631 WMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGS 1690
EP P + G SQ G + GP P GL G+ +GP PG
Sbjct: 634 PGEPGPPGQQ--GNHGSQGLPGPQGLIGTPGEKGPPGNPGIP--GLPGS-DGPLGHPGHE 688
Query: 1691 SPLNAVPCEGPPGSE-PPRRPPPAPHDG--------DRKELPREQPLP--PGPIGTERSQ 1739
P +GPPGS PP P P G K E P G +G + Q
Sbjct: 689 GPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQ 748
Query: 1740 RTDRGTEPGPIRPSHRPGPPVQFGTSDKD 1768
+ PGP GP Q G + ++
Sbjct: 749 --GKPGAPGPRGEDGPEGPKGQAGQAGEE 775
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 114 bits (286), Expect = 8e-25
Identities = 265/1085 (24%), Positives = 340/1085 (31%), Gaps = 259/1085 (23%)
Query: 508 PAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAP 567
PA P+A + E P P PPP P P P P PPA S P PG ++P
Sbjct: 424 PAQRPSASDLQLQLTYLLSERPPRPPPPP---PPPRDGPF-PWPWPPAHSAPRPGTLSSP 479
Query: 568 TLVSGG----------GSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVE 617
+ G T S+ + E + + + G P P + PP P
Sbjct: 480 FPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAP-AWQPASAPPAPHAN 538
Query: 618 PKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV 677
P P + L P + R E ++ ++ +PP P+
Sbjct: 539 PS--------NPFYEALSTPSVLPVISARSPSVSSEYYIRLEEH---------GSPPEPL 581
Query: 678 PPSPPQPVTLGAVPAPQAPPPPPKA-----------LYPGALGRPPPMPPMNFDPRWMMI 726
P+ P+ G VPAPQAP P + L+P P P P + ++
Sbjct: 582 FPNDWDPLDPG-VPAPQAPQAPSEVPQLVSETWASPLFPA----PRPFPAQSSASGSFLL 636
Query: 727 PPYVDP------RLLQGRPPLDFYPPGVHP---------SGLVPRERSDS-GGSSSEPFD 770
+ DP L G P G P G P E S S GG S
Sbjct: 637 SGW-DPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGP 695
Query: 771 RHAPAMLRERGTPPV-----DPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE- 824
P RE + D W G P P EDD +R+E
Sbjct: 696 LPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPP------------EDDSSLRAER 743
Query: 825 --------TPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKI 876
PP PP +L P GA P + PG P P PP
Sbjct: 744 GSLADLPMAPPASAPPEFLD-----PLMGAAAP-------QYPGRGPPPAPP-------- 783
Query: 877 QTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRG 936
PPP P + A P A P G+ S GP P TET + P G+ G
Sbjct: 784 -PPPPPPRAPADPAASPDPPSAVASPGSGLSS--PGPKPGDSGYETETPFSPE-GAFPGG 839
Query: 937 IPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKE 996
EE G P RA PP+P + G P PP P PL L GP+E
Sbjct: 840 GAAEEEGVPRPRA---------------PPEPPDPGAPRP-PPDPGPL-----PLPGPRE 878
Query: 997 TP----PNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFA-RGRGFR---------GTY 1042
P LR D + +G R G A RG G R T
Sbjct: 879 KPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTV 938
Query: 1043 GGRGRGARSREF--RSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEG--SEYEEIP 1098
G G+ A S D R G A G S R E E P
Sbjct: 939 LGNGKQAPSLSLPVNGVTVLENGDQRAPGI---EEKAAENGALGSPEREEKVLENGELTP 995
Query: 1099 KRRRQRGSETGS----ETHE-----SDLAPSDKEAPTPKEGTL-----TQVPLAPPPPGA 1144
RR ++ E G E E L P E + G L T+ P P A
Sbjct: 996 PRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRA 1055
Query: 1145 P-----------PSPA---PARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAK 1190
P P+P PA T+ R P V S R G P P G +P
Sbjct: 1056 PGPWEKTPESWGPAPTIGEPAPETSL-ERAPAPSAVVSSRNGGETAPGPL---GPAPKNG 1111
Query: 1191 SLAP----KKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGG-------SNVGMEDGER 1239
+L P + P TG P + + L G +PV G + GG + G D R
Sbjct: 1112 TLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTR 1171
Query: 1240 PRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAP 1299
P+ + PR R EG+P P S G + AL+ P P
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPG--APDSRAGGDTALSGDGDPPKP 1229
Query: 1300 RRAAAKSPDL-SNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGG 1358
R + P L + Q N E A S A PP+ LTP PG G
Sbjct: 1230 ERKGPEMPRLFLDLGPPQGNSEQIKARLSR--------LSLALPPLTLTP----FPGPG- 1276
Query: 1359 GGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGG 1418
R P G AG++G +GG G
Sbjct: 1277 ------------------------------------PRRPPWEGADAGAAGGEAGGAG-- 1298
Query: 1419 PGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQ 1478
PG ++ ++ E PG P P + + V+ S A +
Sbjct: 1299 -----APGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAAR 1353
Query: 1479 ALAQL 1483
L L
Sbjct: 1354 PLRGL 1358
Score = 108 bits (271), Expect = 4e-23
Identities = 283/1147 (24%), Positives = 372/1147 (32%), Gaps = 232/1147 (20%)
Query: 405 PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKP-PAPE-----DEDEAWRQRRKQSSS 458
PP P PP PPP GP PP R G P P + D D+
Sbjct: 445 PPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGL 504
Query: 459 EISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTP 518
+ E+ARR GAP + + P AP A PS P
Sbjct: 505 NLECLWEKARRGAGRGG----------------------GAPAWQPASAPPAPHANPSNP 542
Query: 519 APPPAVPKELPAPPAPPPASAPTPETEPE-----EPAQAPPAQSTPT------PGVAA-- 565
+ L P P SA +P E E +PP P PGV A
Sbjct: 543 -----FYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQ 597
Query: 566 -------APTLVSGGGST-----------SSTSSGSFEASPVEPQ---LPSKEGPEPPEE 604
P LVS ++ S++SGSF S +P+ +P E
Sbjct: 598 APQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEV 657
Query: 605 VPPPTTPP-VPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLP-PRFQRQQQEQLLKQQQQH 662
+ T P V + E + +G P S G G P + LP P R+ L ++
Sbjct: 658 LGERGTAPWVEEEEEEEEGSSPGEDSSSLG-GGPSRRGPLPCPLCSREGACSCLPLERGD 716
Query: 663 Q---WQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPP--PPPKALYPGALGRPPPMPPM 717
W H P P S + P APP PP+ L P +G P P
Sbjct: 717 AVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDP-LMGAAAPQYP- 774
Query: 718 NFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAM- 776
GR P PP P PR +D S P +P
Sbjct: 775 -------------------GRGP----PPAPPPPPPPPRAPADPAASPDPPSAVASPGSG 811
Query: 777 LRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLA 836
L G P D T TP P P AA+E+ R PP PP P
Sbjct: 812 LSSPGPKPGD------SGYETETPFSPEG-AFPGGGAAEEEGV-PRPRAPPEPPDP---- 859
Query: 837 SYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGP 896
GAP PP PL PGPR P V ++ T ++ T L G
Sbjct: 860 --------GAPRPPPDPGPLPLPGPREKP-----TFVVQVSTEQLLMSLREDVTRNLLGE 906
Query: 897 EAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPP 956
+ G G+G P RE PG +R P G K+ P
Sbjct: 907 KGATARETGPRKAGRG--PGNREK--------VPGLNR----------DPTVLGNGKQAP 946
Query: 957 PPTKVEELPPK---PLEQGDETPKPPKPDPLKITKGKLGGP---KETPPNGNLSPAPRLR 1010
+ LP LE GD+ + P + G LG P ++ NG L+P PR R
Sbjct: 947 SLS----LPVNGVTVLENGDQ--RAPGIEEKAAENGALGSPEREEKVLENGELTP-PR-R 998
Query: 1011 RDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR---EFRGDDGRG 1067
+ + E GE + G + G +S + S F + R
Sbjct: 999 EEKALE-----------NGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERP 1047
Query: 1068 GGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRG---SETGSETHESDLAPSDKEA 1124
T GP P P +T + E P+ +R S S + + AP
Sbjct: 1048 PET-GPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPL-G 1105
Query: 1125 PTPKEGTLT--QVPLAPPPPGAPPSPAPARF-TARGGRVFTPRGVPSRRGRGGGRPPPQV 1181
P PK GTL AP GAP +P R GGR G G G G
Sbjct: 1106 PAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSG---VDA 1162
Query: 1182 CPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPL----------SPVARGGSNGGSN 1231
GW + +PP PLPP E +L P P P A GG
Sbjct: 1163 KAGWVDNTR----PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDT 1218
Query: 1232 VGMEDGERPRRRRHGRAQQQ---DKPPRFRRLKQERENAARGSEGKPSLTL-PASAPGP- 1286
DG+ P+ R G + D P +Q + +R S P LTL P PGP
Sbjct: 1219 ALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPR 1278
Query: 1287 ----EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPP 1342
E A A A + ++ D+ EE E A+ R +
Sbjct: 1279 RPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAA 1338
Query: 1343 PVLLTPKAVGTPGGGGGGAVPGISAMSRG-------DLSQRAK------DLSKRSFSSQR 1389
PV P V + + G+ RG +L ++ K D++ F +
Sbjct: 1339 PV---PVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQET 1395
Query: 1390 PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPG 1449
P E + P G + S+ P PG G +PS + E
Sbjct: 1396 PTNELSVQAP----PEGDTDPSTPPAPPTPPHPATPGDG----FPSNDSGFGGSFEWAED 1447
Query: 1450 LPLPPPP 1456
PL PPP
Sbjct: 1448 FPLLPPP 1454
Score = 98.6 bits (244), Expect = 6e-20
Identities = 226/968 (23%), Positives = 308/968 (31%), Gaps = 243/968 (25%)
Query: 356 EGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPP 415
EG ++ +G+ P E G++G +P E + + + G P+ + PLP P
Sbjct: 642 EGRGAGETLAGD--PAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCP 699
Query: 416 -------------HRGPA-GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEIS 461
RG A WG G P P P ++D + R R S +++
Sbjct: 700 LCSREGACSCLPLERGDAVAGWG--------GHPALGCPHPPEDDSSLRAERG-SLADLP 750
Query: 462 LAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPA-- 519
+A + AP + L +P AAP P
Sbjct: 751 MAPPAS-------------------------------APPEFL--DPLMGAAAPQYPGRG 777
Query: 520 PPPAVPKELPAPPAPPPASAPTPETEPEEP-AQAPPAQSTPTPGVAAAPTLVSGGGSTSS 578
PPPA P PP PPP + P P+ P A A P +PG
Sbjct: 778 PPPA-----PPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPG------------ 820
Query: 579 TSSGSFEASPVEPQLPSKEGPEPPEE-VPPPTTPPVPKVEPKGDGIGPTRQPPSQG---L 634
SG +P P+ G EE VP P PP P +P G R PP G L
Sbjct: 821 -DSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPP-DP-----GAPRPPPDPGPLPL 873
Query: 635 GYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQ 694
P+ + + + +Q L++ + +A T + P VP
Sbjct: 874 PGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLN 933
Query: 695 APPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV 754
P LG P ++ + + D R PG+
Sbjct: 934 RDPT--------VLGNGKQAPSLSLPVNGVTVLENGDQRA-----------PGIE----- 969
Query: 755 PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPL-----TSP 809
E++ G+ P +R + TPP + A + A + L T P
Sbjct: 970 --EKAAENGALGSP-EREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPP 1026
Query: 810 LRQAADEDDKGMR----SETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLP 865
+ ++ G+R +E PP P + PE+ P P I P E P
Sbjct: 1027 KSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGE-PAPETSLERAP 1085
Query: 866 WPP-------GSDEVAKIQTPPPKK---EPPKEETAQLTG-----PEAGR---------- 900
P G + P PK EP E A TG P AGR
Sbjct: 1086 APSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAP 1145
Query: 901 -----KPARGVGSGGQG-----------------PPPPRRESRTETRWGPRPGSSRRGIP 938
P G GSG PPPP + R R P P +R +
Sbjct: 1146 VGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPR---RLEPAPPRARPEVA 1202
Query: 939 PE-EPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPK------PPKPDPLKITKGKL 991
PE EPGAP RAG + PPKP +G E P+ PP+ + +I K +L
Sbjct: 1203 PEGEPGAPDSRAGG----DTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQI-KARL 1257
Query: 992 GGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARS 1051
P L+P P GP R G G G G G
Sbjct: 1258 SRLSLALPPLTLTPFP-----------GPGPRRPPWEGADAGAAGGEAGGAGAPGPAEED 1306
Query: 1052 REFRSYREFRGDDGRG-GGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGS 1110
E E ++ G GP P R S P R +
Sbjct: 1307 GEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGAD 1366
Query: 1111 ETHESDLAPS---------------DKEAPT-------PKEGTLTQVPLAPPPPGAPPSP 1148
E +S+L D+E PT P EG P PP P PP P
Sbjct: 1367 EPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTD--PSTPPAPPTPPHP 1424
Query: 1149 A------PARFTARGGR--------VFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAP 1194
A P+ + GG + P G P R P + PG PPA+ AP
Sbjct: 1425 ATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALET-PG--PPAR--AP 1479
Query: 1195 KKPPTGPL 1202
P GP+
Sbjct: 1480 DARPAGPV 1487
Score = 86.7 bits (213), Expect = 2e-16
Identities = 279/1227 (22%), Positives = 388/1227 (31%), Gaps = 294/1227 (23%)
Query: 649 RQQQEQL----LKQQQQHQWQQHQQGS-APPTPVPPSPPQPVTLGAVPAPQAPPPPPKAL 703
RQQ +L LK W Q PP P + + L + + + P PPP
Sbjct: 394 RQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPP--- 450
Query: 704 YPGALGRPPPMPPMNFDPRWMMIPPYVDPR---LLQGRPPLDFYPPGVHPSGLVPRERSD 760
PP PP + W P + PR L P LD +P G P ++ S
Sbjct: 451 --------PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFP-GADPDDVLTVTESS 501
Query: 761 SGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKG 820
G + +++ R G P P +A PA ++P +A
Sbjct: 502 RGLNLECLWEKARRGAGRGGGAPAWQPA--------SAPPAPHANPSNPFYEALSTP--- 550
Query: 821 MRSETPPVPPPPPYLAS--YPGFPENGAPGPPISRFPLE----EPGPRPLPWPPGSDEVA 874
S P + P ++S Y E+G+P P+ FP + +PG P EV
Sbjct: 551 --SVLPVISARSPSVSSEYYIRLEEHGSPPEPL--FPNDWDPLDPGVPAPQAPQAPSEVP 606
Query: 875 KIQTP-------PPKKEPPKEETAQLTGPEAGRKP-ARGVGSGGQGPPPPRRESRTETRW 926
++ + P + P + +A + +G P RG G G P R W
Sbjct: 607 QLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPW 666
Query: 927 GPRPGSSRRGIPPEEP----GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDET------- 975
G P E G P R GP+ P ++ PLE+GD
Sbjct: 667 VEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLC-SREGACSCLPLERGDAVAGWGGHP 725
Query: 976 ----PKPPKPDP-LKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGE 1030
P PP+ D L+ +G L PP + AP E + P
Sbjct: 726 ALGCPHPPEDDSSLRAERGSLADLPMAPP----ASAPP-------EFLDPLM-------- 766
Query: 1031 YFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRT------- 1083
GA + ++ GRG P PP PR
Sbjct: 767 -----------------GAAAPQY---------PGRGPPPAPPPPPPPPRAPADPAASPD 800
Query: 1084 -ASETRSEGSEYEEIPKRRRQRGSET-----------GSETHESDLAPSDKEAPTPKEGT 1131
S S GS + G ET G E + P + P P +
Sbjct: 801 PPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPD-- 858
Query: 1132 LTQVPLAPPPPGAPPSPAPAR---FTAR-------------------GGRVFTPRGV-PS 1168
P PP PG P P P F + G + T R P
Sbjct: 859 -PGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPR 917
Query: 1169 RRGRGGGRPPPQVCPGWSPPAKSLAP-KKPPTGPLPPSKEPLKE---KLIPGPLSPVARG 1224
+ GRG G + PG + L K+ P+ LP + + E + PG A
Sbjct: 918 KAGRGPGNR--EKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAEN 975
Query: 1225 GSNGG---SNVGMEDGERPRRRRHGRAQQQDK-----------------PPRFRRLKQER 1264
G+ G +E+GE RR +A + + PP+ E
Sbjct: 976 GALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSEN 1035
Query: 1265 ENAA--RGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWE 1322
R +E +P T P APGP E T + PAP +P+ S E
Sbjct: 1036 GGLRFPRNTE-RPPETGPWRAPGPWEK-TPESWGPAPT-IGEPAPETS----------LE 1082
Query: 1323 TASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSK 1382
A S S R G + AP P+ PK G PG +
Sbjct: 1083 RAPAPSAVVSSRNGGETAPGPLGPAPK--------NGTLEPGTERRA------------- 1121
Query: 1383 RSFSSQRPGMERQNRRPGPGG-KAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSR 1441
P R PG G GS G + G G PGG G G K W + +R
Sbjct: 1122 -------PETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGW---VDNTR 1171
Query: 1442 PPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKP 1501
P +PP PLPPPP + P ++ A PR +P
Sbjct: 1172 P---QPPPPPLPPPP-------------EAQPRRLEPA----------------PPRARP 1199
Query: 1502 GLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRR 1561
+ AP+G P +R SG P E GP + PR + P
Sbjct: 1200 EV--APEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEM------PRLFLDLGPPQGNSE 1251
Query: 1562 ERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRK 1621
+ R L +LPP + F G P P E D G +
Sbjct: 1252 QIKARLSRL--SLALPPLTLTPFPGPGPR--RPPWEGADAGAAG-----------GEAGG 1296
Query: 1622 SYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAE 1681
+ P E E ED E + D G + GP R++P + +A+
Sbjct: 1297 AGAPGPAEEDGED----ED----EDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSAD 1348
Query: 1682 GPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQR- 1740
RP + + P SE R+ GD +Q P + +
Sbjct: 1349 ADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEG 1408
Query: 1741 -TDRGTEPGPIRPSHRPGPPVQFGTSD 1766
TD T P P P H P F ++D
Sbjct: 1409 DTDPSTPPAPPTPPHPATPGDGFPSND 1435
Score = 55.5 bits (132), Expect = 6e-07
Identities = 181/792 (22%), Positives = 253/792 (31%), Gaps = 168/792 (21%)
Query: 58 PPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTP 117
PP + SL+AE +G+ ++ + P ++ E DP A+ Q P P PA P
Sbjct: 732 PPEDDSSLRAE-RGSLADLPMAPPA----SAPPEFLDPLMG-AAAPQYPGRGPPPAPPPP 785
Query: 118 ASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAH-GDGGRASSLLSRFSRE-EFPTLQA 175
P R PA P +P PS V S + G GD G + + FS E FP A
Sbjct: 786 PP--PPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETE--TPFSPEGAFPGGGA 841
Query: 176 AGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGL 235
A +++ + + PG P + GP L GP K P +
Sbjct: 842 A--EEEGVPRPRAPPEPPDPGAPRPPPDP---------GPLPLPGPREK------PTFVV 884
Query: 236 QPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQ----GPYRYPTPDGPSRFPRVAGPRGS 291
Q S R + + GP+ GP G +R P V G
Sbjct: 885 QVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQ 944
Query: 292 GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD 351
P + L PV ++L+ + + ++ ++G G+ E EE ++
Sbjct: 945 APSLSL--PVNGVTVLENGDQRAPGIEEKAAENGALGSPER-----------EEKVLENG 991
Query: 352 EEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAE---------TSRPPET- 401
E + +GE R PEA K + PP + +E T RPPET
Sbjct: 992 ELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETG 1051
Query: 402 ---EPGP---------PAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKP----PAPEDE 445
PGP PAP P P P R G P PAP++
Sbjct: 1052 PWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNG 1111
Query: 446 D-EAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRL 504
E +RR + A R R A +D K G D
Sbjct: 1112 TLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDN-- 1169
Query: 505 KAEPAAPPAAPSTPAPPPAVPKEL-PAPPAPPPASAPTPET-----------------EP 546
P PP P P PP A P+ L PAPP P AP E +P
Sbjct: 1170 -TRPQPPP--PPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDP 1226
Query: 547 EEPAQA--------------------------------PPAQSTPTPGVAAA--PTLVSG 572
+P + PP TP PG P +
Sbjct: 1227 PKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGAD 1286
Query: 573 GGSTSSTSSGSFEASPVEPQLPSK-EGPEPPEEVPPP------------TTPPVPKVEPK 619
G+ + G+ P E + E E EE P PVP V
Sbjct: 1287 AGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSS 1346
Query: 620 GDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPP 679
D P +GL P + +++ +++ Q +
Sbjct: 1347 ADADAAR---PLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQ 1403
Query: 680 SPPQPVTLGAVPAPQAPPPPPKALYPG--------ALG-----------RPPPMPPMNFD 720
+PP+ T + P APP PP PG G PPP PP+ F
Sbjct: 1404 APPEGDTDPSTPP--APPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFS 1461
Query: 721 PRWMMIPPYVDP 732
R+ + P P
Sbjct: 1462 -RFSVSPALETP 1472
Score = 49.7 bits (117), Expect = 3e-05
Identities = 189/788 (23%), Positives = 252/788 (31%), Gaps = 160/788 (20%)
Query: 1448 PGLPLPPPPPSSSAVFRLDQVIHSNPA-GIQQALAQLSSRQGSVTAPGGHPRHK------ 1500
PG+P P P + S V +L ++P + SS GS G P +
Sbjct: 591 PGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETL 650
Query: 1501 PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKR 1560
G P G P E + G S PG +GG P G P P
Sbjct: 651 AGDPAEVLGERGTAPWVEEEEEEEEGSS-------PGEDSSSLGGGP-SRRGPLPCPLCS 702
Query: 1561 RERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESR-DTGTEALTPHIWNRLHTATS 1619
RE L + +++ LG P P + R + G+ A P
Sbjct: 703 REGACSCLPLERGDAVAGWGGHPALGC-PHPPEDDSSLRAERGSLADLP--------MAP 753
Query: 1620 RKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVD--LSGDSQVSSGPCSQRSSPDGGLK 1677
S P ++P M +P G + D S P S +SP GL
Sbjct: 754 PASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLS 813
Query: 1678 GAAEGPPKRPGGS--------SPLNAVPCEGPPGSEP---PRRPPPAPHDGDRKELPREQ 1726
P +PG S SP A P G E PR PP P G + P
Sbjct: 814 S----PGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPG 869
Query: 1727 PLP-PGP---------IGTER---SQRTD-----------RGTEPGPIRPSHRPG----- 1757
PLP PGP + TE+ S R D E GP + PG
Sbjct: 870 PLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKV 929
Query: 1758 -----PPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQ 1812
P G + L L V E + P + A S E +
Sbjct: 930 PGLNRDPTVLGNGKQAPSLSLPVNGVTVLENG-----DQRAPGIEEKAAENGALGSPERE 984
Query: 1813 SKNLDSGHCVP-----EPSSSGQRLYPE-----VFYGSAGPSSSQI----SGGAM---DS 1855
K L++G P + +G+ PE + G P S+ +GG ++
Sbjct: 985 EKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNT 1044
Query: 1856 QLHPNSGGFR-PGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGK 1914
+ P +G +R PG P P PAP ++L A S + ++ G
Sbjct: 1045 ERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAP-------SAVVSSRNGG 1097
Query: 1915 LPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQS----GFL 1970
A G L P P P+T P L GG++ G
Sbjct: 1098 ETAPGPLGPAPKNGTLEPGTERRAPETG------GAPRAPGAGRLDLGSGGRAPVGTGTA 1151
Query: 1971 PSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPA-P 2029
P G P VD++ V+ P PPP PPP P QP L PP A P
Sbjct: 1152 PGGGPGSG-----VDAKAGWVDNTRPQPPPPPLPPP-------PEAQPRRLEPAPPRARP 1199
Query: 2030 ATRVLPSPARPFPASLGRAELH-----PVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFS 2084
P P + G L P + + +L +LG PP G S
Sbjct: 1200 EVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLG-------PPQGNS-- 1250
Query: 2085 GLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPG 2144
++KA R R+ L A PP L P P R PP EG A
Sbjct: 1251 ---EQIKA---------RLSRLSL---ALPPLTLTPFPGPGPRR--PPWEGADAGAAGGE 1293
Query: 2145 SRGDKEPG 2152
+ G PG
Sbjct: 1294 AGGAGAPG 1301
Score = 42.7 bits (99), Expect = 0.004
Identities = 72/296 (24%), Positives = 95/296 (32%), Gaps = 36/296 (12%)
Query: 353 EGAEGHRDSQSA-----SGEERPPEADGKKGNSP-----------NSEPPTPKTAWAETS 396
EG G DS++ SG+ PP+ + K P NSE + + +
Sbjct: 1204 EGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLA 1263
Query: 397 RPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQS 456
PP T P P P PP AG G G+ G P EDEDE + + +
Sbjct: 1264 LPPLTLTPFPGPGPRRPPWEGADAGAAG--GEAGGAGAPGPAEEDGEDEDEDEEEDEEAA 1321
Query: 457 SSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPS 516
+ + R R + A A L+ L + D+ +E S
Sbjct: 1322 APGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVS 1381
Query: 517 TPAPPPAVPKELPAPPAPPPASAPTP-ETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGS 575
+ P AP +T+P P P TPG G S
Sbjct: 1382 FHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPG--------DGFPS 1433
Query: 576 TSSTSSGSFEASPVEPQLPSKEGPEPP------EEVPPPTTPPVPKVEPKGDGIGP 625
S GSFE + P LP P PP P TP P P GP
Sbjct: 1434 NDSGFGGSFEWAEDFPLLPP---PGPPLCFSRFSVSPALETPGPPARAPDARPAGP 1486
Score = 31.6 bits (70), Expect = 8.8
Identities = 50/206 (24%), Positives = 70/206 (33%), Gaps = 30/206 (14%)
Query: 1975 PAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVL 2034
PAQ+ + QL + PP PPP PPP P P PP+ P P T
Sbjct: 424 PAQRPSASDLQLQLTYL-LSERPPRPPPPPPPPRDGPF-PWPWPPA---HSAPRPGTLSS 478
Query: 2035 PSP-------ARPFPASLGRAELHPVELKPFQDYQKLSSNLGG----------PGSSRTP 2077
P P A P + L+ + + + GG P +
Sbjct: 479 PFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHAN 538
Query: 2078 PTGRSFSGLN--SRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKPWERTGP--PPR 2133
P+ + L+ S L + V + L + SPP+ L P W+ P P
Sbjct: 539 PSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPL--FPNDWDPLDPGVPAP 596
Query: 2134 EGPSRRAEEPG--SRGDKEPGLPPPR 2157
+ P +E P S P P PR
Sbjct: 597 QAPQAPSEVPQLVSETWASPLFPAPR 622
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 110 bits (276), Expect = 1e-23
Identities = 355/1488 (23%), Positives = 456/1488 (30%), Gaps = 343/1488 (23%)
Query: 354 GAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPK-PPL 412
G G + G+ PP A G KG+ + PT + P PGPP P+ P
Sbjct: 83 GPIGLSGEKGMRGDRGPPGAAGDKGD----KGPTGVPGFPGLDGIPG-HPGPPGPRGKPG 137
Query: 413 PPPHRGPAGNWGPPGDYPDRG-GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRR 471
H G G+ G PG G G P P + E K +S I AV+ + R
Sbjct: 138 MSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGE--------KGNSVFILGAVKGIQGDR 189
Query: 472 EEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPA--PPPAVPKELP 529
+ L L +GA PA P P P PP P P
Sbjct: 190 GDPG--------------LPGLPGSWGA------GGPAGPTGYPGEPGLVGPPGQPGR-P 228
Query: 530 APPAPPPASAPTPETEPEEPAQAPPAQSTPTP----------------GVAAAPTLVSGG 573
P +P E Q Q +P P G+ P +V
Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQ----QGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLP 284
Query: 574 GSTSSTSSGSFEASPVEPQLPSKEGPE-PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQ 632
G A E +P GP P P P + KG+ +G P
Sbjct: 285 GPPGRKGESGIGAKG-EKGIPGFPGPRGDPGSYGSPGFPGL-----KGE-LGLVGDPGLF 337
Query: 633 GLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPA 692
GL PK +G P V +PP P+
Sbjct: 338 GLIGPKGDPG-------------------------NRGHPGPPGVLVTPPLPL------- 365
Query: 693 PQAPPPPPKALYPGALGRP----PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGV 748
+ PP P +PG G PP PP + P QG P L PG+
Sbjct: 366 -KGPPGDPG--FPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGL----PGL 418
Query: 749 HPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTS 808
+P + G +P P +G P VG+ P +
Sbjct: 419 PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGN---PGPQGIKGKVG 475
Query: 809 PLRQAADEDDKGMRS----ETPPVPPPPPYLASYPGFP----ENGAPGPPISRFPLEEPG 860
P + +KG E P+ PP P PG P G G P +PG
Sbjct: 476 PPGGRGPKGEKGNEGLCACEPGPMGPPGP-----PGLPGRQGSKGDLGLPGWLGTKGDPG 530
Query: 861 PRPLPWPPGSDEVAKIQTPPPKKEPPKEET-AQLTGPEAGRKPARGVGSGGQGPPPPRRE 919
P PPG PP K + +++ G + R P G GQ P R+
Sbjct: 531 PPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQ-PGSHGRD 589
Query: 920 SRTETRWGPRPGSSRRGIPPEEPG-----APPRRAGPIKKP------PPPTKVEE-LPPK 967
+ P P P G PP +AGP+ P PP + +P
Sbjct: 590 GHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGH 649
Query: 968 PLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRG 1027
P +G + K K D + G + PP + P P+ GP G
Sbjct: 650 PGVRGPDGLKGQKGDTISCNVTYPG--RHGPPGFDGPPGPK-------GFPGPQGAPGLS 700
Query: 1028 RGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGG-PNHPPAPRGRTASE 1086
+ G +G G G A +R GD G GG G P PP P G
Sbjct: 701 GSD------GHKGRPGTPGT-AEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGS---- 749
Query: 1087 TRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPP 1146
P Q+G P+ P + L+ VP P G P
Sbjct: 750 -----------PGVNGQKGIPGD---------PAFGHLGPPGKRGLSGVPGIKGPRGDPG 789
Query: 1147 SPAPARFTARGGRVFTPRGVPSRRGRGG--GRPPPQVCPGWSPPAKSLAPKKPPTGPLPP 1204
P A G P G+P G G GR PG P + P P P
Sbjct: 790 CPG-----AEG-----PAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQP 839
Query: 1205 SKEPLKEKLIPG-PLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQE 1263
+PG P SP A GG +VG G A + P R
Sbjct: 840 G--------LPGYPGSPGAPGGKGQPGDVGPP----------GPAGMKGLPGLPGR---- 877
Query: 1264 RENAARGSEGKPSLTLPAS---APGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE 1320
A G G P + P PGP P R P
Sbjct: 878 --PGAHGPPGLPGIPGPFGDDGLPGPP--------GPKGPRGLPGFPG------------ 915
Query: 1321 WETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAM--SRGDLSQRAK 1378
F ER P P A G PG G +PG + ++G +
Sbjct: 916 ---------FPGER-----GKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG- 960
Query: 1379 DLSKRSFSSQR--PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG-PGRGDKRSWPS 1435
D + + SQ+ PG PGP G G G G G GR G PGR P
Sbjct: 961 DEGEMAIISQKGTPG------EPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYG----PP 1010
Query: 1436 PKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGG 1495
+R P E+ PG P PP PP S+ + +G + PG
Sbjct: 1011 GFHRGEPGEKGQPGPPGPPGPPGSTGL------------------------RGFIGFPG- 1045
Query: 1496 HPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDP--HFEEPGPMVRGVGGTPR----- 1548
PG P P P + + R G DP HF PGP +G G+P
Sbjct: 1046 ----LPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGP--KGEPGSPGCPGHF 1099
Query: 1549 DSAGVSPFP----PKRRERPPRKPELLQEESLPPPHSSGFLGSKP---EGPGPQAESRDT 1601
++G P P+ P P P H L +P PGP+ D
Sbjct: 1100 GASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDP 1159
Query: 1602 GTEALTPHI--------WNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGV 1653
G P I N LH +K + +S + P P V
Sbjct: 1160 GIPG-PPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP---------------V 1203
Query: 1654 DLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPA 1713
+ G P S SP G +GPP PG S P G + P PP
Sbjct: 1204 GIPGLKGERGDPGSPGISPPG--PRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPG 1261
Query: 1714 PHDGDRKELPREQPLPPGPIGTERSQRTDRGT--EPGPIRPSHRPGPP 1759
+ PR P PPG G+ R + G PGP P PGPP
Sbjct: 1262 DQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPP 1309
Score = 107 bits (268), Expect = 1e-22
Identities = 367/1568 (23%), Positives = 469/1568 (29%), Gaps = 358/1568 (22%)
Query: 211 GGRGPDELEG-PDSKLHHGH--DP-----RGGLQPSGPPQFPPYRGMMPPFMY------- 255
G GP G P H+G DP RG L P GP P +G ++
Sbjct: 125 GHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKG 184
Query: 256 ------PPYLPFPPPY----GPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPS 305
P LP P GP GP YP G + GP G GRP
Sbjct: 185 IQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPG------LVGPPGQP---------GRPG 229
Query: 306 ILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSAS 365
+ + Q+ + G G+ E F + G +G +
Sbjct: 230 LKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYK--------GEKGIKGIPGMV 281
Query: 366 GEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLP-PPHRGPAGNWG 424
G PP G+ G E P PG P K L G G G
Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341
Query: 425 PPGDYPDRG--GPP---CKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQ 479
P GD +RG GPP PP P
Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLP------------------------------------- 364
Query: 480 EERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPP--- 536
LK G P + + PP P P + PP P
Sbjct: 365 ----------LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG 414
Query: 537 -ASAPTPETEPEEPAQAPPAQSTP-TPGVAAAPTLVS-GGGSTSSTSSGSFEASPVEPQL 593
P P P AP P +PG+ AP L G S S G+ ++ ++
Sbjct: 415 LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKV 474
Query: 594 --PSKEGPE-----------PPEEVPPPTTPPVP-KVEPKGD-----GIGPTRQPPSQGL 634
P GP+ P + PP P +P + KGD +G P G
Sbjct: 475 GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGA 534
Query: 635 GYP-----KYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPP--------------- 674
P K+ S PP + + + ++ + + H+ ++ G PP
Sbjct: 535 EGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDG--PPGFPGQPGSHGRDGHA 592
Query: 675 ----TPVPPSPPQPVTLG--AVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPP 728
P PP + T G P P PP + P LG P P P P P
Sbjct: 593 GEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGP-PGERGHPGVPGHPG 651
Query: 729 YVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPK 788
P L+G+ +P P G P + AP G D
Sbjct: 652 VRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAP------GLSGSDGH 705
Query: 789 LAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYL---ASYPGFPENG 845
G TA P + +KG PP PP P + PG P G
Sbjct: 706 KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765
Query: 846 APGPPISRFPLEEP---GPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKP 902
GPP R P GPR P PG++ A I L GP+ GR+
Sbjct: 766 HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGI-----------PGFLGLKGPK-GREG 813
Query: 903 ARGVGSGGQGPPPPRRESRTETRWGPR-PGSSRRGIP--PEEPGAPPRRAGP-IKKPPPP 958
G G GPP E R P PG + G+P P PGAP + P PP P
Sbjct: 814 HAGF-PGVPGPPGHSCE-----RGAPGIPG--QPGLPGYPGSPGAPGGKGQPGDVGPPGP 865
Query: 959 TKVEELPPKPLEQGDETPK--PPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYE 1016
++ LP P G P P P P G G P P G L P +
Sbjct: 866 AGMKGLPGLPGRPGAHGPPGLPGIPGPFG-DDGLPGPPGPKGPRG-LPGFPGFPGERG-- 921
Query: 1017 RVGPTSCRGRGRGEYFARG-------RGFRGTYGGRGRGARSREFRSYREFRGDDGRGGG 1069
+ G C G +GE +G RG RG G G E + +G G G
Sbjct: 922 KPGAEGCPG-AKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQ-KGTPGEPGP 979
Query: 1070 TGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKE 1129
G P + + E P R G G + P P
Sbjct: 980 PGDDGFPGERGDKGTPGMQGRRGE----PGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST 1035
Query: 1130 GT--LTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSP 1187
G P P G P SP P F+ G+ RG G + P + P
Sbjct: 1036 GLRGFIGFPGLPGDQGEPGSPGPPGFS----------GIDGARGPKGNKGDP--ASHFGP 1083
Query: 1188 PAKSLAPKKPPTGPLPPSKEPLKEKL----IPGPLSPVARGGSNGGSNVGMEDGERPRRR 1243
P PK P P P + I GP R G G S G+
Sbjct: 1084 P----GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPG 1139
Query: 1244 RHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAA 1303
G+ + P RG +G P + P GP
Sbjct: 1140 LRGQPGEMGDP------------GPRGLQGDPGIPGPPGIKGP----------------- 1170
Query: 1304 AKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVP 1363
+ SP L+ + + + + AS G + PP VG PG G P
Sbjct: 1171 SGSPGLNGLHGLKGQKGTKGAS----------GLHDVGPP-----GPVGIPGLKGERGDP 1215
Query: 1364 GISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGG-------- 1415
G +S PG + PGP G +G G + G
Sbjct: 1216 GSPGIS-------------------PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPD 1256
Query: 1416 GGGPGGRTGPGRGDKRSWPSPKN--------RSRPPE---ERPPGLPLPPPPPSSSAVFR 1464
G PG + PG R P P R P + PPG P PP PP
Sbjct: 1257 PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPG 1316
Query: 1465 LD-QVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAP--QGPSPRPPTRYEPQ 1521
D + P G QG PG P + GLP P +GP+ P R EP
Sbjct: 1317 CDGKDGQKGPVG-------FPGPQGPHGFPG--PPGEKGLPGPPGRKGPTGLPGPRGEP- 1366
Query: 1522 RVNSGLSSDPHFEEPGPMVRGVGGTP--RDSAGVSPFPPKRRERPPRKPELLQEESLP-- 1577
P + P + G+ G P R G P R P P E L
Sbjct: 1367 -------GPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGM---RGPSGPGCKGEPGLDGR 1416
Query: 1578 -----------PPHSSGFLGSK--PEGPGPQAESRDTGTEALTPHIWNR----LHTATSR 1620
PP G G P GPGP D G + P LH+ T +
Sbjct: 1417 RGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQ 1476
Query: 1621 KSYRPSSM 1628
+ P M
Sbjct: 1477 EPTCPLGM 1484
Score = 91.7 bits (226), Expect = 7e-18
Identities = 213/861 (24%), Positives = 273/861 (31%), Gaps = 173/861 (20%)
Query: 195 PGPSLRPQNSTTWRDG-----GGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGM 249
PGP P S + DG G G E+ GP DP G + P PP
Sbjct: 691 PGPQGAPGLSGS--DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPG 748
Query: 250 MPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKE 309
P +P P +G GP P G S P + GPRG P G P L
Sbjct: 749 SPGVNGQKGIPGDPAFGHLGP---PGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGL 805
Query: 310 DNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEER 369
K +E G+ G + S E GA G G
Sbjct: 806 KGPK-----GREGHAGFPGVPGPPGH--------------SCERGAPGIPGQPGLPGYPG 846
Query: 370 PPEADGKKGNSPNSEPPTP---KTAWAETSRP----PETEPGPPAPKP----PLPPPHRG 418
P A G KG + PP P K RP P PG P P P PP +G
Sbjct: 847 SPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKG 906
Query: 419 PAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRM 478
P G G PG +P G P P + E + + L + +E M
Sbjct: 907 PRGLPGFPG-FPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEM 965
Query: 479 Q-EERRAACAEKLKRLDEKF-------GAPDKR-LKAEPA---------------APPAA 514
++ E D+ F G P + + EP P
Sbjct: 966 AIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGP 1025
Query: 515 PSTPAPP-----------PAVPKELPAPPAP-PPASAPTPETEPEEPAQAPPAQSTPTPG 562
P P PP P +P + P +P PP + + + PA PG
Sbjct: 1026 PGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPG 1085
Query: 563 VAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDG 622
P S G F AS E LP +GP P P P P G
Sbjct: 1086 PKGEP--------GSPGCPGHFGASG-EQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHG 1136
Query: 623 I-GPTRQPPSQGLGYPKYQKS-----LPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTP 676
+ G QP G P+ + PP + L + Q+ +G++
Sbjct: 1137 MPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHD 1196
Query: 677 VPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP-PPMPPMNFDPRWMMIPPYVDPRLL 735
V PP PV + + + P P PG G+ PP PP + P P
Sbjct: 1197 V--GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGP--------PGPAGA 1246
Query: 736 QGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDV 795
GR P D PG P D+ P RG P P L D+
Sbjct: 1247 TGRAPKDIPDPG-------------------PPGDQGPPGPDGPRGAPG-PPGLPGSVDL 1286
Query: 796 FTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFP----ENGAPGP-- 849
P D G+ PP PP PP Y GFP ++G GP
Sbjct: 1287 LRGEPG----------------DCGLPG--PPGPPGPPGPPGYKGFPGCDGKDGQKGPVG 1328
Query: 850 -PISRFPLEEPGP---RPLPWPPGSDEVAKIQTPPPKKEPPKE-----ETAQLTGPEAGR 900
P + P PGP + LP PPG + P + PP + L G R
Sbjct: 1329 FPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMR 1388
Query: 901 KPARGVG-SGGQGPPPPRRESRTETRWGPRPG-SSRRGIP--PEEPGAPPRRA-----GP 951
P +G G +GP P + PG RRG+ P PG P R+ G
Sbjct: 1389 GPEGAMGLPGMRGPSGPGCKG--------EPGLDGRRGVDGVPGSPGPPGRKGDTGEDGY 1440
Query: 952 IKKPPPPTKVEELPPKPLEQG 972
P PP + + PK G
Sbjct: 1441 PGGPGPPGPIGDPGPKGFGPG 1461
Score = 85.5 bits (210), Expect = 5e-16
Identities = 356/1466 (24%), Positives = 448/1466 (30%), Gaps = 285/1466 (19%)
Query: 818 DKGMRSETPPVPPPPPYLASYPGFPE----------NGAPGPPISRFPLEEPGPRPLPWP 867
+KG R PP PP P G P G GPP + + GP +P
Sbjct: 60 EKGSRG--PPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF 117
Query: 868 PGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARG-VGSGGQGPPPPRRESRTETRW 926
PG D + PP + P + + G RG +G GG P + + + +
Sbjct: 118 PGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVF 177
Query: 927 ---------GPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPK 977
G R G+P P AGP P P V P +P G
Sbjct: 178 ILGAVKGIQGDRGDPGLPGLPGSWGAGGP--AGPTGYPGEPGLVGP-PGQPGRPG----- 229
Query: 978 PPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRG 1037
K +P KG++G P E G SP P L + P C +G +G
Sbjct: 230 -LKGNPGVGVKGQMGDPGEVGQQG--SPGPTLLVE------PPDFCLYKGEKGI----KG 276
Query: 1038 FRGTYGGRGRGARSREFRSYREFRGDDGRGG-GTGGPNHPPAPRGRTASETRSEGSEYEE 1096
G G G R +G+ G G G G P PRG + S GS
Sbjct: 277 IPGMVGLPGPPGR----------KGESGIGAKGEKGIPGFPGPRG----DPGSYGS--PG 320
Query: 1097 IPKRRRQRG-----SETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA-P 1150
P + + G G + D P ++ P P G L PL P G P P P
Sbjct: 321 FPGLKGELGLVGDPGLFGLIGPKGD--PGNRGHPGP-PGVLVTPPL--PLKGPPGDPGFP 375
Query: 1151 ARFTARGGRVFTPRGVPSRRGRGG-------GRPPPQVCPGW-SPPAKSLAPKKPPTGPL 1202
R+ G P G P GR G G P PQ PG P ++ P +P + P
Sbjct: 376 GRYGETGD--VGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPG 433
Query: 1203 PPSKEPLKEKLIPG-PLSPVARG--GSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRR 1259
P K PG P P A G G G S + G + G+ PP R
Sbjct: 434 KPGK--------PGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKV----GPPGGRG 481
Query: 1260 LKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANE 1319
K E +G+EG L A PGP P P P D
Sbjct: 482 PKGE-----KGNEG-----LCACEPGP-------MGPPGP----PGLPGRQGSKGDLGLP 520
Query: 1320 EWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPG--GGGGGAVPGISAMSRGDLSQRA 1377
W G K P P P A G PG G G + P + ++GD+
Sbjct: 521 GW-------------LGTKGDPGP----PGAEGPPGLPGKHGASGPPGNKGAKGDM---- 559
Query: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPK 1437
S+ G + + GP G G GS G G G GP + + P K
Sbjct: 560 -------VVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGK 612
Query: 1438 NRSRP--PEER-----PPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSV 1490
P P + PPGL P PP P G++ S +V
Sbjct: 613 GFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTIS--CNV 670
Query: 1491 TAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLS-SDPHFEEPG----------PM 1539
T PG RH P P GP P + P GLS SD H PG P
Sbjct: 671 TYPG---RHGPPGFDGPPGPKGFPGPQGAP-----GLSGSDGHKGRPGTPGTAEIPGPPG 722
Query: 1540 VRGVGGTP--RDSAGVSPFPPKRRERPPRKPELLQEESLP---------PPHSSGFLG-- 1586
RG G P G SP P PP P + ++ +P PP G G
Sbjct: 723 FRGDMGDPGFGGEKGSSPVGP---PGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVP 779
Query: 1587 ------SKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPS-SMEPWMEPLSPFE 1639
P PG + + G L H P S E +
Sbjct: 780 GIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQP 839
Query: 1640 DVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCE 1699
+ G S G GP + P + A GPP PG P
Sbjct: 840 GLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLP 899
Query: 1700 GPPGSEPPRRPPPAPHDGDRKELPREQPLP-----PGPIGTERSQRTDRGTEPGPIRPSH 1754
GPPG + PR P P + P + P PG G DRG
Sbjct: 900 GPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMS-GLPGDRGLR-------- 950
Query: 1755 RPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSK 1814
G G + ++ ++ E + P R + P +
Sbjct: 951 --GAKGAIGPPGDEGEMAIISQKGTPGEPGPPGD--DGFPGERGDKGTPGMQGRRGEPGR 1006
Query: 1815 NLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPY 1874
G EP GQ P G GP S G + P G PG+P +
Sbjct: 1007 YGPPGFHRGEPGEKGQPGPP----GPPGPPGSTGLRGFIGFPGLPGDQG-EPGSPGPPGF 1061
Query: 1875 RSQPLYLPP-----------GPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYP 1923
P GP P G F S Q + P G P
Sbjct: 1062 SGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHF-GASGEQGLPGIQGPRGSPGRP 1120
Query: 1924 PPSFLYSPAFCPSP--LPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLL 1981
P P CP +P P P P PG PSG+P L
Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLH 1180
Query: 1982 PMVDSQLPVVNFGSLPPAPPPAPPPLSLL------PVGPALQPPSLAVR--PPPAPATRV 2033
+ Q L PP P + L P P + PP + PP P +
Sbjct: 1181 GL-KGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSG 1239
Query: 2034 LPSPARPFPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKAT 2093
P PA + GRA + P D GP R P G L+
Sbjct: 1240 PPGPA----GATGRAPKDIPDPGPPGD-----QGPPGPDGPRGAPGPPGLPGSVDLLRGE 1290
Query: 2094 PST-----------------YSGVFRTQRVDLYQQASP-----PDALRWIP-KPWER--T 2128
P Y G D Q P P P P E+
Sbjct: 1291 PGDCGLPGPPGPPGPPGPPGYKGFPGCDGKD--GQKGPVGFPGPQGPHGFPGPPGEKGLP 1348
Query: 2129 GPPPREGPSRRAEEPGSRGDKEPGLP 2154
GPP R+GP+ PG RG EPG P
Sbjct: 1349 GPPGRKGPTGL---PGPRG--EPGPP 1369
Score = 55.8 bits (133), Expect = 4e-07
Identities = 262/1125 (23%), Positives = 333/1125 (29%), Gaps = 245/1125 (21%)
Query: 1173 GGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNV 1232
G G+ C G P+K GP P PGP P+ G+ G +
Sbjct: 38 GSGKKYIGPCGGRDCSVCHCVPEKGSRGPPGP----------PGPQGPIGPLGAPGPIGL 87
Query: 1233 GMEDGERPRRRRHGRAQQQ-DKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALT 1291
E G R R G A + DK P G G P L PGP
Sbjct: 88 SGEKGMRGDRGPPGAAGDKGDKGPT-------------GVPGFPGLDGIPGHPGP----- 129
Query: 1292 TVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAV 1351
P PR P +S N + + + G + A P +
Sbjct: 130 -----PGPRG----KPGMSGHNGSRGDPGFP-------------GGRGALGP----GGPL 163
Query: 1352 GTPGGGGG--------GAVPGISAMSRGDLSQRAKDLSKRSFSSQRP-GMERQNRRPGPG 1402
G PG G GAV GI RGD S + P G + GP
Sbjct: 164 GHPGEKGEKGNSVFILGAVKGIQG-DRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPP 222
Query: 1403 GKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPE----------ERPPGLPL 1452
G+ G G G G G PG ++ P P PP+ + PG+
Sbjct: 223 GQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVG 282
Query: 1453 PPPPPSSSAVFRLDQVIHSNPAGI-----------QQALAQLSSRQGSVTAPG------- 1494
P PP + G L G V PG
Sbjct: 283 LPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGP 342
Query: 1495 -------GHPRHKPGLPQAP----QGPSPRP--PTRYEPQRVNSGLSSDPH-FEEPGPMV 1540
GHP PG+ P +GP P P RY + + G P PG
Sbjct: 343 KGDPGNRGHP-GPPGVLVTPPLPLKGPPGDPGFPGRY-GETGDVGPPGPPGLLGRPGEAC 400
Query: 1541 RGVGGT--PRDSAGVSPFP-----PKRRERPPRKPELLQEESLP-PPHSSGFLGSK---- 1588
G+ G P+ G+ P P R + P KP LP P G GS
Sbjct: 401 AGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYC 460
Query: 1589 ------PEG-------PGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPL 1635
P+G PG + + G E L + P M P P
Sbjct: 461 SVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLC--------------ACEPGPMGPPGPPG 506
Query: 1636 SPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNA 1695
P G + S+ D G+ ++ GP P K A GPP G +
Sbjct: 507 LP-----GRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVV 561
Query: 1696 VPCEGPPGSEPPRRPP-----PAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTE-PGP 1749
+G G P PP P H D + P PPG + T G PGP
Sbjct: 562 SRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPG----DHEDATPGGKGFPGP 617
Query: 1750 IRPSHR-----------PGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRD 1798
+ P + PGPP + G + D LK +K T S P
Sbjct: 618 LGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677
Query: 1799 WELLPSAAASAEPQSKNLDSGHCVPEPS-SSGQRLYPEVFYGSAGPSSSQISG--GAMDS 1855
P K P S S G + P P +++I G G
Sbjct: 678 -----PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRP------GTPGTAEIPGPPGFRGD 726
Query: 1856 QLHPNSGGFR----------PGTPSLHPYR---SQPLYLPPGPAPPSALLSGLALKGQFL 1902
P GG + PG+P ++ + P + GP L +KG
Sbjct: 727 MGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRG 786
Query: 1903 DFSTMQATELGKLPAGGVLYPPPSFLYSPAF--CPSPLPDTSLLQVRQDLPSPSDFYSTP 1960
D A +P L P F P P P S + +P P
Sbjct: 787 DPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGP-PGHSCERGAPGIPGQPGLPGYP 845
Query: 1961 LQPG-----GQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPL--SLLPVG 2013
PG GQ G + PA LP LP PP P P P LP
Sbjct: 846 GSPGAPGGKGQPGDVGPPGPAGMKGLP----GLPGRPGAHGPPGLPGIPGPFGDDGLPGP 901
Query: 2014 PALQPPSLAVRPPPAPATRVLPSP-----ARPFPASLGRAEL--------HPVELKPFQD 2060
P + P P P R P A+ P G + L + P D
Sbjct: 902 PGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961
Query: 2061 YQKLS--SNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDAL 2118
+++ S G PG PP F G K TP R PP
Sbjct: 962 EGEMAIISQKGTPGEP-GPPGDDGFPGERGD-KGTPGMQGRRGEPGRY------GPPGFH 1013
Query: 2119 RWIPKPWERTGPPPREGPSRRA------EEPGSRGDK-EPGLPPP 2156
R P + GPP GP PG GD+ EPG P P
Sbjct: 1014 RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGP 1058
Score = 32.0 bits (71), Expect = 6.7
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 12/52 (23%)
Query: 403 PGPPAPKPPLPP----------PHRGPAGNWGPPGDYPDRG--GPPCKPPAP 442
PGPP P+ P+ P +G G+ GPPG D+G GP P P
Sbjct: 67 PGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP 118
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 145,455,881
Number of Sequences: 37866
Number of extensions: 12120853
Number of successful extensions: 241579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1369
Number of HSP's successfully gapped in prelim test: 3329
Number of HSP's that attempted gapping in prelim test: 53760
Number of HSP's gapped (non-prelim): 98864
length of query: 2157
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2039
effective length of database: 13,779,330
effective search space: 28096053870
effective search space used: 28096053870
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.