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Search of human proteins with 145701025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
(2778 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 6029 0.0
gi|46410931 attractin-like 1 [Homo sapiens] 222 5e-57
gi|21450863 attractin isoform 2 [Homo sapiens] 213 2e-54
gi|21450861 attractin isoform 1 [Homo sapiens] 213 2e-54
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 100 2e-20
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 99 6e-20
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 95 1e-18
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 94 2e-18
gi|134244285 Notch homolog 3 [Homo sapiens] 93 3e-18
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 93 4e-18
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 93 4e-18
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 90 3e-17
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 89 5e-17
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 89 5e-17
gi|66346695 fibrillin 2 precursor [Homo sapiens] 87 2e-16
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 87 3e-16
gi|21264602 laminin alpha 5 [Homo sapiens] 87 3e-16
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 86 5e-16
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 86 5e-16
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 85 9e-16
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 85 9e-16
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 84 2e-15
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 83 3e-15
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 83 3e-15
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 83 3e-15
gi|126091152 cubilin [Homo sapiens] 83 3e-15
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 83 4e-15
gi|56237021 fibrillin 3 precursor [Homo sapiens] 83 4e-15
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 82 7e-15
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 81 1e-14
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 6029 bits (15641), Expect = 0.0
Identities = 2778/2778 (100%), Positives = 2778/2778 (100%)
Query: 1 MALGKVLAMALVLALAVLGSLSPGARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWL 60
MALGKVLAMALVLALAVLGSLSPGARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWL
Sbjct: 1 MALGKVLAMALVLALAVLGSLSPGARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWL 60
Query: 61 IEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLL 120
IEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLL
Sbjct: 61 IEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLL 120
Query: 121 HLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGS 180
HLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGS
Sbjct: 121 HLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGS 180
Query: 181 HGTCASPLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG 240
HGTCASPLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG
Sbjct: 181 HGTCASPLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG 240
Query: 241 LLAVFGGQDLNNALGDLVLYNFSANTWESWDLSPAPAARHSHVAVAWAGSLVLMGGELAD 300
LLAVFGGQDLNNALGDLVLYNFSANTWESWDLSPAPAARHSHVAVAWAGSLVLMGGELAD
Sbjct: 241 LLAVFGGQDLNNALGDLVLYNFSANTWESWDLSPAPAARHSHVAVAWAGSLVLMGGELAD 300
Query: 301 GSLTNDVWAFSPLGRGHWELLAPPASSSSGPPGLAGHAAALVDDVWLYVSGGRTPHDLFS 360
GSLTNDVWAFSPLGRGHWELLAPPASSSSGPPGLAGHAAALVDDVWLYVSGGRTPHDLFS
Sbjct: 301 GSLTNDVWAFSPLGRGHWELLAPPASSSSGPPGLAGHAAALVDDVWLYVSGGRTPHDLFS 360
Query: 361 SGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRV 420
SGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRV
Sbjct: 361 SGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRV 420
Query: 421 NSTELFHVDRHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDG 480
NSTELFHVDRHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDG
Sbjct: 421 NSTELFHVDRHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKCYEDG 480
Query: 481 IFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDL 540
IFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDL
Sbjct: 481 IFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDL 540
Query: 541 MAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSRDPECSWCQGACQAAPPPGTPLGACPAA 600
MAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSRDPECSWCQGACQAAPPPGTPLGACPAA
Sbjct: 541 MAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSRDPECSWCQGACQAAPPPGTPLGACPAA 600
Query: 601 SCLGLGRLLGDCQACLAFSSPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGW 660
SCLGLGRLLGDCQACLAFSSPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGW
Sbjct: 601 SCLGLGRLLGDCQACLAFSSPTAPPRGPGTLGWCVHNESCLPRPEQARCRGEQISGTVGW 660
Query: 661 WGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNTSQPDKEEVGRWVAHQEKETRRLQRPG 720
WGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNTSQPDKEEVGRWVAHQEKETRRLQRPG
Sbjct: 661 WGPAPVFVTSLEACVTQSFLPGLHLLTFQQPPNTSQPDKEEVGRWVAHQEKETRRLQRPG 720
Query: 721 SARLFPLPGRDHKYAVEIQGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSS 780
SARLFPLPGRDHKYAVEIQGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSS
Sbjct: 721 SARLFPLPGRDHKYAVEIQGQLNGSAGPGHSELTLLWDRTGVPGGSEISFFFLEPYRSSS 780
Query: 781 CTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDC 840
CTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDC
Sbjct: 781 CTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDC 840
Query: 841 HACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCA 900
HACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCA
Sbjct: 841 HACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCA 900
Query: 901 WCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNE 960
WCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNE
Sbjct: 901 WCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNE 960
Query: 961 DNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHP 1020
DNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHP
Sbjct: 961 DNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHP 1020
Query: 1021 RATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPP 1080
RATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPP
Sbjct: 1021 RATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPP 1080
Query: 1081 PTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG 1140
PTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG
Sbjct: 1081 PTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG 1140
Query: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRA 1200
CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRA
Sbjct: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRA 1200
Query: 1201 LLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLT 1260
LLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLT
Sbjct: 1201 LLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLT 1260
Query: 1261 FSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLH 1320
FSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLH
Sbjct: 1261 FSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLH 1320
Query: 1321 WEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMA 1380
WEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMA
Sbjct: 1321 WEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMA 1380
Query: 1381 LCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSADTASRF 1440
LCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSADTASRF
Sbjct: 1381 LCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSADTASRF 1440
Query: 1441 LHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGPGPSPRS 1500
LHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGPGPSPRS
Sbjct: 1441 LHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGPGPSPRS 1500
Query: 1501 FHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAVAGHTLTA 1560
FHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAVAGHTLTA
Sbjct: 1501 FHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAVAGHTLTA 1560
Query: 1561 RRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLY 1620
RRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLY
Sbjct: 1561 RRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLY 1620
Query: 1621 VFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQP 1680
VFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQP
Sbjct: 1621 VFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQP 1680
Query: 1681 GSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPD 1740
GSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPD
Sbjct: 1681 GSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPD 1740
Query: 1741 EFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGSRLYISGGFGGVALGRL 1800
EFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGSRLYISGGFGGVALGRL
Sbjct: 1741 EFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGSRLYISGGFGGVALGRL 1800
Query: 1801 LALTLPPDPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRR 1860
LALTLPPDPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRR
Sbjct: 1801 LALTLPPDPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRR 1860
Query: 1861 LRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQREVFW 1920
LRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQREVFW
Sbjct: 1861 LRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQREVFW 1920
Query: 1921 AGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPM 1980
AGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPM
Sbjct: 1921 AGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPM 1980
Query: 1981 PVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGC 2040
PVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGC
Sbjct: 1981 PVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGC 2040
Query: 2041 GRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRP 2100
GRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRP
Sbjct: 2041 GRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRP 2100
Query: 2101 GASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGC 2160
GASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGC
Sbjct: 2101 GASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGC 2160
Query: 2161 VNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLP 2220
VNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLP
Sbjct: 2161 VNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLP 2220
Query: 2221 LFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSED 2280
LFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSED
Sbjct: 2221 LFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSED 2280
Query: 2281 EAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGT 2340
EAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGT
Sbjct: 2281 EAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGT 2340
Query: 2341 CQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKR 2400
CQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKR
Sbjct: 2341 CQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKR 2400
Query: 2401 RALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQ 2460
RALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQ
Sbjct: 2401 RALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQ 2460
Query: 2461 PPPAPPPPPPPADGGPRGAGDPGGAGASSGPGAPAEPRVREVWPRGLITYVTVTEPSAVL 2520
PPPAPPPPPPPADGGPRGAGDPGGAGASSGPGAPAEPRVREVWPRGLITYVTVTEPSAVL
Sbjct: 2461 PPPAPPPPPPPADGGPRGAGDPGGAGASSGPGAPAEPRVREVWPRGLITYVTVTEPSAVL 2520
Query: 2521 VVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHID 2580
VVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHID
Sbjct: 2521 VVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHID 2580
Query: 2581 LFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD 2640
LFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD
Sbjct: 2581 LFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPD 2640
Query: 2641 PTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPATTAGLRAGP 2700
PTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPATTAGLRAGP
Sbjct: 2641 PTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPATTAGLRAGP 2700
Query: 2701 ITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGGGGAGGSGHGT 2760
ITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGGGGAGGSGHGT
Sbjct: 2701 ITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSALVTLRHRLHEYCGGGGGAGGSGHGT 2760
Query: 2761 GAGRKGLLSQDNLTSMSL 2778
GAGRKGLLSQDNLTSMSL
Sbjct: 2761 GAGRKGLLSQDNLTSMSL 2778
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 222 bits (565), Expect = 5e-57
Identities = 173/630 (27%), Positives = 265/630 (42%), Gaps = 74/630 (11%)
Query: 24 GARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTY 83
G + C+G R L E G++TDG NY C WLIE P + L F TEC++
Sbjct: 87 GDQCQHCQG-RFKLTEPSGYLTDGPINYKYKTKCTWLIEG-YPNAVLRLRFNHFATECSW 144
Query: 84 DYLFVYDGDSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNA 135
D+++VYDGDS PL+A LSG P P + +SG LLH FSDA YNL GFN
Sbjct: 145 DHMYVYDGDSIYAPLIAVLSGLIVPEIRGNETVPEVVTTSGYALLHFFSDAAYNLTGFNI 204
Query: 136 SFRFSLCPGGCQSHGQCQ-----PPGV-CACEPGWGGPDCGLQECSAYCGS--HGTC-AS 186
+ + CP C HG+C P V C C+ W G C + C A CGS HG C +
Sbjct: 205 FYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGEACDIPYCKANCGSPDHGYCDLT 264
Query: 187 PLGPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVF 245
C C + G C L++ + NV FS +G A G + V
Sbjct: 265 GEKLCVCNDSWQGPDCSLNVPSTESYWILPNVK----PFSPSVGRASHKAVLHGKFMWVI 320
Query: 246 GGQDLNNALGDLVL-YNFSANTWESWDLSPAPAARHSHVAVAWAGSLVLMGG--ELADGS 302
GG N + +VL YN ++ W S P R+ H + ++ + GG E DG+
Sbjct: 321 GGYTFNYSSFQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGN 380
Query: 303 LTNDVWAFSPLGRGHWELLAPPASSSSGPPGLAGHAAALVD----DVWLYVSGGRTPHDL 358
+T+++W F+ + W P + GH+A +++ DV + + G +
Sbjct: 381 VTDELWVFN-IHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYG 439
Query: 359 FSSGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSV 418
++S + + + S + W G GH+ V+ ++++ VHGG++
Sbjct: 440 YTSSIQEYHISSNT---WLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYG 496
Query: 419 RVNSTELFHVDRHVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTH---YQEEK 475
V+ + V+ WT LK + R H+A ++ M+++GGN H K
Sbjct: 497 LVDDLYKYEVNTKTWTILK-----ESGFARYLHSAVLINGAMLIFGGNTHNDTSLSNGAK 551
Query: 476 CYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGR 535
C+ Y + C +W P+ R+ H A V+ GS + + GG+S
Sbjct: 552 CFSADFLAYDIACDEWKI--------LPKPNLHRDVNRFGHSAVVINGS-MYIFGGFSSV 602
Query: 536 PRGDLMAYKVPPFVFQAPAPDYHLDYCSMYTDHSVCSR---DPECSWCQGACQAAPPPGT 592
D++ YK P C + D +C +C W + C++ T
Sbjct: 603 LLNDILVYKPP--------------NCKAFRDEELCKNAGPGIKCVWNKNHCESWESGNT 648
Query: 593 P---LGACPAASCLGLGRL--LGDCQACLA 617
CP + R DC +C A
Sbjct: 649 NNILRAKCPPKTAASDDRCYRYADCASCTA 678
Score = 177 bits (448), Expect = 2e-43
Identities = 272/1205 (22%), Positives = 428/1205 (35%), Gaps = 296/1205 (24%)
Query: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201
+PC+ R G C SG C + C LC PG+ GD C + C GR
Sbjct: 61 KPCE-------RTGSC--FSGRCV------NSTC-LCDPGWVGD-----QC-QHCQGRFK 98
Query: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPGLSY-----CVWVVSATEELQPCAPGTLCPP 1256
LT S G GP ++Y C W++ P +
Sbjct: 99 LTEPS-----------------GYLTDGP-INYKYKTKCTWLIEGY-------PNAV--- 130
Query: 1257 LTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGL 1316
L L F+ +T C+ ++ +DG + V S LI P V SG
Sbjct: 131 LRLRFN-HFATECSWDHMYVYDGDSIYAPLIAVLS--GLIVPEIRGNETVPEVVTT-SGY 186
Query: 1317 LVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGP 1375
+LH+ ++ + + GFN C P +C +C C C + W G
Sbjct: 187 ALLHFFSDAAYNLTGFNIFYSINSC----PNNCSGHGKCTTSVSVPSQVYCECDKYWKGE 242
Query: 1376 HCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSA 1434
C + C NC + G C+ + +C+C + + GPDC+ + + W L + + +
Sbjct: 243 ACDIPYCKANCGS-PDHGYCDLTGEKLCVCNDSWQGPDCSLNVPSTESYW-ILPNVKPFS 300
Query: 1435 DTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGP 1494
+ R H+ ++ G +W+ GG + Y++ W G P
Sbjct: 301 PSVGRASHK---AVLHGK--FMWVIGGYTFNYSSFQMVLNYNLESSIWNV-------GTP 348
Query: 1495 --GPSPRSFHAAAYVPAGRGAMYLLGG---LTAGGVTRDFWVLNLTTLQWRQEKAPQTV- 1548
GP R H+ A +++ GG G VT + WV N+ + W K P +
Sbjct: 349 SRGPLQRYGHSLALYQEN---IFMYGGRIETNDGNVTDELWVFNIHSQSW-STKTPTVLG 404
Query: 1549 --ELPAVAGHTLTAR----RGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPP 1602
+ AV GH+ R + ++++ GYS G+ + EY +++ TW+ G
Sbjct: 405 HGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIV 464
Query: 1603 TGLYGHSAVYHEATDSLYVFGGFRFHVELAAPS------PELYSLHCPDRTWSLLAPSQG 1656
G YGH++VY E T S+YV GG++ A P +LY +TW++L S
Sbjct: 465 QGGYGHTSVYDEITKSIYVHGGYK-----ALPGNKYGLVDDLYKYEVNTKTWTILKESGF 519
Query: 1657 AKRDRMRNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPR 1716
A R + + + A+ GG + H
Sbjct: 520 A----------------------------RYLHSAVLINGAMLIFGG-----NTH----- 541
Query: 1717 PRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLL---PDLTRSASVGPPMEE 1773
DT + G + +F L Y + C+ W + P+L R +
Sbjct: 542 ----------NDTSLSNGAKCFSADF----LAYDIACDEWKILPKPNLHRDVN------- 580
Query: 1774 SVAHAVAAVGSRLYISGGFGGVALGRLLALTLPPDPCRLLSSPEACNQSG---ACTWCHG 1830
H+ + +YI GGF V L + L P C+ E C +G C W
Sbjct: 581 RFGHSAVVINGSMYIFGGFSSVLLNDI--LVYKPPNCKAFRDEELCKNAGPGIKCVWNKN 638
Query: 1831 ACLSGDQAHRLGCGGSPCSP-MPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKW 1889
C S + + + C P S + C R C+ C A+T C+W
Sbjct: 639 HCESWESGNTNNILRAKCPPKTAASDDRCYRYADCASC-------------TANTNGCQW 685
Query: 1890 CTNCPEGACIGRNGSCT----SENDCRINQREVFWAGNCSEAACGAADCEQCTREGKCMW 1945
C + CI N +C+ + C + ++ C++ C+ C+ C W
Sbjct: 686 ---CDDKKCISANSNCSMSVKNYTKCHVRNEQI-----CNK----LTSCKSCSLNLNCQW 733
Query: 1946 TRQFKRTGETRRILSVQPTYDWTCFSHSLLNV-SPMPVESSPPLPCPTPCHLLPNCTSCL 2004
+R E + + + W+ + L V S + L C +L N S
Sbjct: 734 D---QRQQECQALPAHLCGEGWSHIGDACLRVNSSRENYDNAKLYC---YNLSGNLASLT 787
Query: 2005 DSKGADGGWQHCVWSSSLQQCLSP---------SYLPLRCMAGGCGRLLR---GPESCSL 2052
SK + QQ +SP SY M+ L+ G + S
Sbjct: 788 TSKEVEFVLDEI--QKYTQQKVSPWVGLRKINISYWGWEDMSPFTNTTLQWLPGEPNDSG 845
Query: 2053 GCAQATQCALC-LRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPP 2111
CA + A+ L+ C A G C + +S ++ C +P C
Sbjct: 846 FCAYLERAAVAGLKANPCTSMA-----NGLVCEKPVVSPNQNARPCKKP--------CSL 892
Query: 2112 EDECANGHHD------CNETQNCHDQPHGYECSCKTGYTMDNMTGLCRP-------VCAQ 2158
C+N + C+ T+ C D + Y S G ++ T C P C Q
Sbjct: 893 RTSCSNCTSNGMECMWCSSTKRCVDS-NAYIISFPYGQCLEWQTATCSPQNCSGLRTCGQ 951
Query: 2159 -----GCVNGSCVEPD-----HC-----RCHFGFVGRN----------CSTE-------- 2185
GC G C +P HC R +G + C E
Sbjct: 952 CLEQPGC--GWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFI 1009
Query: 2186 ----CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRG 2241
C+CN HS C + C C+N T G C+ C+P + G GG C C C G
Sbjct: 1010 QCPACQCNGHSTCIN---NNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTAC--TCSG 1064
Query: 2242 NSHIC 2246
+++IC
Sbjct: 1065 HANIC 1069
Score = 105 bits (261), Expect = 8e-22
Identities = 57/191 (29%), Positives = 84/191 (43%), Gaps = 23/191 (12%)
Query: 879 CPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRS 938
C CS R +C +C +N +C WC ST C AY+ +P+G C W + S ++
Sbjct: 886 CKKPCSLRTSCSNCTSNGMECMWCSSTKRCVDSNAYIISFPYGQCLEWQTATCSP---QN 942
Query: 939 CDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGP--LGGGNCSLWVGEGLGLPVAL 996
C G TC +CL+ CGWC + N G C++G GP L G + S V + P
Sbjct: 943 CSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNLCPKEK 1002
Query: 997 PARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC----------HCQRGYQGDGISH 1046
W++ +CP +C+ +TC+N + +C C GY GD +
Sbjct: 1003 NYEWSFIQCP--------ACQCNGHSTCINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNG 1054
Query: 1047 CNRTCLEDCGH 1057
T GH
Sbjct: 1055 GQCTACTCSGH 1065
Score = 84.0 bits (206), Expect = 2e-15
Identities = 70/256 (27%), Positives = 99/256 (38%), Gaps = 33/256 (12%)
Query: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027
T ++ L+ P+ + PC PC L +C++C S G + C+W SS ++C+
Sbjct: 864 TSMANGLVCEKPVVSPNQNARPCKKPCSLRTSCSNCT-SNGME-----CMWCSSTKRCVD 917
Query: 2028 PSYLPLRCMAGGCGRLLRGPESCS-LGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEG 2086
+ + G C L +CS C+ C CL +P CGWC G G C+EG
Sbjct: 918 SNAYIISFPYGQC--LEWQTATCSPQNCSGLRTCGQCLEQPGCGWCNDPSNTGRGHCIEG 975
Query: 2087 GLSGPR------------DGLTCGR-PGASWAFLSCPPEDECANGHHDC---NETQNCHD 2130
GP D C + W+F+ C P +C NGH C N + C +
Sbjct: 976 SSRGPMKLIGMHHSEMVLDTNLCPKEKNYEWSFIQC-PACQC-NGHSTCINNNVCEQCKN 1033
Query: 2131 QPHGYEC-SCKTGYTMDNMT-GLCRPVCAQGCVNGSCVEPDHCRCHF-GFVGRNCSTECR 2187
G +C C GY D G C G N + C C G G C
Sbjct: 1034 LTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHANICHLHTGKCFCTTKGIKGDQCQL--- 1090
Query: 2188 CNRHSECAGVGARDHC 2203
C+ + G R C
Sbjct: 1091 CDSENRYVGNPLRGTC 1106
Score = 67.4 bits (163), Expect = 2e-10
Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 10/101 (9%)
Query: 1096 CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRG 1155
C C+ HS C C++C++ T G+ C+ C PG +G+ T C C C+GH +
Sbjct: 1014 CQCNGHSTCINNN--VCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGHAN---- 1067
Query: 1156 HCDNLSGLCFCQDH-TEGAHCQLCSP--GYYGDPRAGGSCF 1193
C +G CFC +G CQLC Y G+P G+C+
Sbjct: 1068 ICHLHTGKCFCTTKGIKGDQCQLCDSENRYVGNP-LRGTCY 1107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 49/173 (28%), Positives = 65/173 (37%), Gaps = 48/173 (27%)
Query: 2572 FRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFA 2631
F Q +DL FF FFSCF L + ++WK KQ + + + L+E +MASRPFA
Sbjct: 1221 FSQHNTIMDLVQFFVTFFSCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFA 1280
Query: 2632 KVTVCFPPDPTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPA 2691
V V G F R GP+ G
Sbjct: 1281 SVDVAL------------EVGAEQTEFLR-----------------GPLEGA-------- 1303
Query: 2692 TTAGLRAGPITLEPTEDGMAGVATLLLQLPGG-----PHAPNGACLGSALVTL 2739
PI +EP A V T+ L LP G P +G + SAL+ +
Sbjct: 1304 ------PKPIAIEPCAGNRAAVLTVFLCLPRGSSGAPPPGQSGLAIASALIDI 1350
Score = 55.8 bits (133), Expect = 6e-07
Identities = 28/61 (45%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFR-ECGGR 1199
C CQCNGH C N + C++ T G CQ C PGYYGDP GG C C G
Sbjct: 1011 CPACQCNGHST-----CINNNVCEQCKNLTTGKQCQDCMPGYYGDPTNGGQCTACTCSGH 1065
Query: 1200 A 1200
A
Sbjct: 1066 A 1066
Score = 39.3 bits (90), Expect = 0.055
Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 36/139 (25%)
Query: 780 SCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGG---------SLLVLVPTL 830
+C+ +C CL GCGWC + G HC + + G S +VL L
Sbjct: 942 NCSGLRTCGQCLEQPGCGWCNDPS----NTGRGHCIEGSSRGPMKLIGMHHSEMVLDTNL 997
Query: 831 CPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCE 890
CP +E + Q P C+ + ++ + C E+C L + + C+
Sbjct: 998 CP--KEKNYEWSFIQCPACQCNGHSTCINNNVC-------------EQCKNLTTGK-QCQ 1041
Query: 891 DCL-------ANSSQCAWC 902
DC+ N QC C
Sbjct: 1042 DCMPGYYGDPTNGGQCTAC 1060
Score = 37.7 bits (86), Expect = 0.16
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 14/89 (15%)
Query: 1041 GDGISHCNRTCLEDC-GHGVC----SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRD 1095
G I + +C +C GHG C S P C CD W + P C +
Sbjct: 201 GFNIFYSINSCPNNCSGHGKCTTSVSVPSQVYCECDKYWKGE--------ACDIPYCKAN 252
Query: 1096 CGCSFHSHCRKRGPGFCDECQDWTWGEHC 1124
CG H +C G C C D G C
Sbjct: 253 CGSPDHGYCDLTGEKLC-VCNDSWQGPDC 280
Score = 37.0 bits (84), Expect = 0.27
Identities = 19/66 (28%), Positives = 25/66 (37%), Gaps = 18/66 (27%)
Query: 2309 KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSP 2368
+C CQCNGH+ C NN C+ + QC C ++G P
Sbjct: 1010 QCPACQCNGHS-----------TCINNNVCEQCKNLTTGK-------QCQDCMPGYYGDP 1051
Query: 2369 LGGQQC 2374
G QC
Sbjct: 1052 TNGGQC 1057
Score = 33.5 bits (75), Expect = 3.0
Identities = 33/155 (21%), Positives = 56/155 (36%), Gaps = 34/155 (21%)
Query: 823 LLVLVPTLCPLCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPL 882
+LV P C + C C W+++ ++ G L++ +CPP
Sbjct: 607 ILVYKPPNCKAFRDEELCKNAGPGIKCVWNKNHCESWES-----GNTNNILRA--KCPPK 659
Query: 883 -------CSQRLTCEDCLANSSQCAWC------QSTHTCFLFAAYLARYPHGGCRGWDDS 929
C + C C AN++ C WC + C + + C ++
Sbjct: 660 TAASDDRCYRYADCASCTANTNGCQWCDDKKCISANSNCSMSVKNYTK-----CHVRNEQ 714
Query: 930 VHSE-PRCRSCDGFLTC------HEC--LQSHECG 955
+ ++ C+SC L C EC L +H CG
Sbjct: 715 ICNKLTSCKSCSLNLNCQWDQRQQECQALPAHLCG 749
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 213 bits (542), Expect = 2e-54
Identities = 159/536 (29%), Positives = 239/536 (44%), Gaps = 49/536 (9%)
Query: 32 GQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDG 91
G R L + GFVTDG GNY C WLIE P + L F TEC++D+L+VYDG
Sbjct: 133 GGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYVYDG 191
Query: 92 DSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCP 143
DS PL+A+ SG P P + A+SG LLH FSDA YNL GFN ++ F +CP
Sbjct: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCP 251
Query: 144 GGCQSHGQCQPPG-----VCACEPGWGGPDCGLQECSAYCG--SHGTC-ASPLGPCRCEP 195
C G+C+ C C W G C + C+ CG G C +S + C C
Sbjct: 252 NNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFS 311
Query: 196 GFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVFGGQDLNNAL 254
+ G C + + NQ +W R+ + ++ A G ++ V GG N++
Sbjct: 312 DWQGPGCSVPVPANQ--SFW----TREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSD 365
Query: 255 GDLVL-YNFSANTWESWDLS-PAPAARHSHVAVAWAGSLVLMGGEL-ADGSLTNDVWAFS 311
++VL Y+ ++ W + S R+ H + + + GG++ + G++TN++ F
Sbjct: 366 YNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFH 425
Query: 312 PLGRGHWELLAPPASSSSGPPGLAGHAAALVDD-VWLYVSGGRTPHDLFSSGLFRFRLDS 370
+ W LL P A G + H L + V + V G P + S + + LD
Sbjct: 426 -IHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDK 484
Query: 371 TSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDR 430
+ W + G GHS V+ +RAL VHGG++ +A + + VD
Sbjct: 485 NT---WSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDT 541
Query: 431 HVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEE---KCYEDGIFFYHLG 487
+WT LK R HTA ++ M+V+GGN H KC+ Y +
Sbjct: 542 QMWTILKDSRFF-----RYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIA 596
Query: 488 CHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAY 543
C +W P R+ H +AVL S + V GG++ D++ +
Sbjct: 597 CDRW--------SVLPRPDLHHDVNRFGH-SAVLHNSTMYVFGGFNSLLLSDILVF 643
Score = 153 bits (386), Expect = 3e-36
Identities = 268/1179 (22%), Positives = 414/1179 (35%), Gaps = 237/1179 (20%)
Query: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201
RPC NG G C+ +G C C G CQ CGGR
Sbjct: 103 RPC-VNG------GRCNPGTGQCVCPAGWVGEQCQ------------------HCGGRFR 137
Query: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPG----LSYCVWVVSATEELQPCAPGTLCPPL 1257
LT S G GPG + C W++ P + +
Sbjct: 138 LTGSS-----------------GFVTDGPGNYKYKTKCTWLIEGQ-------PNRI---M 170
Query: 1258 TLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCG---QRRDRPLTVQ--- 1311
L F+ +T C+ ++ +DG + L+AAF G RD TV
Sbjct: 171 RLRFN-HFATECSWDHLYVYDGDSIYAP---------LVAAFSGLIVPERDGNETVPEVV 220
Query: 1312 ALSGLLVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQ 1370
A SG +LH+ ++ + + GFN + C P +C EC + + C C +
Sbjct: 221 ATSGYALLHFFSDAAYNLTGFNITYSFDMC----PNNCSGRGECKISNSSDTVE-CECSE 275
Query: 1371 GWAGPHCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMD 1429
W G C + C +NC G CN S + C C + GP C+ + Q W
Sbjct: 276 NWKGEACDIPHCTDNCG-FPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEY 334
Query: 1430 SRLSADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGA 1489
S L AS +V+G +W+ GG + Y ++ R W +
Sbjct: 335 SNLKLPRASH------KAVVNGN--IMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSV 386
Query: 1490 EDGGPGPSPRSFHAAAYVPAGRGAMYLLGGL--TAGGVTRDFWVLNLTTLQWRQEKAPQT 1547
+ R H+ A + +Y+ GG + G VT + V ++ W P+
Sbjct: 387 NN----VVVRYGHSLALY---KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVL-LTPKA 438
Query: 1548 VELPAVAGHT---LTARRG-LSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPT 1603
E AV GH+ +T + G + +L++ G+ P G+ + EY L TW G
Sbjct: 439 KEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQ 498
Query: 1604 GLYGHSAVYHEATDSLYVFGGFR-FHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRM 1662
G YGHS+VY T +LYV GG++ F + +LY + W++L S+ +
Sbjct: 499 GGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHT 558
Query: 1663 RNVRGSSRGL--GQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLF 1720
+ + + G + S G + + L P L R
Sbjct: 559 AVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPR--PDLHHDVNRFG 616
Query: 1721 HASALLGDTMVVLGGRSDPDEFSSDVLLY-QVNCNAWLLPDLTRSASVGPPMEESVAHAV 1779
H++ L TM V GG + SD+L++ C+A +A G V
Sbjct: 617 HSAVLHNSTMYVFGGFNSL--LLSDILVFTSEQCDAHRSEAACLAAGPG-------IRCV 667
Query: 1780 AAVGSRLYISGGFGGVALGRLLAL------TLPPDPCRLLSSPEACN-QSGACTWCHGAC 1832
GS IS L TL D C + +C + C WC+ C
Sbjct: 668 WNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHC 727
Query: 1833 LSGDQAHRLGCGGSPCSPMPRSPEE-----CRRLRTCSECLARHPRTLQPGDGEASTPRC 1887
+ + H G P++ C + +C C +P + E
Sbjct: 728 VPRN--HSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQE------ 779
Query: 1888 KWCTNCPEGAC-IGRN---GSCTSENDCRIN--QREVFWAGNCSEAACGAADCEQCTREG 1941
C PE C IG + SC + N ++F + + A T +
Sbjct: 780 --CIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLA-------SLTTQK 830
Query: 1942 KCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCT 2001
K + + R ++ + +S W +NVS E P +
Sbjct: 831 KVEFVLKQLRIMQSSQSMSKLTLTPWVGLRK--INVSYWCWEDMSPFT--------NSLL 880
Query: 2002 SCLDSKGADGGWQHCVWSSSLQQCLSPSYL-PLRCMAGGCGRLLR-GPESCSLGCAQATQ 2059
+ S+ +D G+ + S + + + + PL C R + C CA T
Sbjct: 881 QWMPSEPSDAGFCGILSEPSTRGLKAATCINPLN--GSVCERPANHSAKQCRTPCALRTA 938
Query: 2060 CALCLR-RPHCGWC----------AWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLS 2108
C C C WC A+ G+CME W +S
Sbjct: 939 CGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCME------------------WYTMS 980
Query: 2109 -CPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVE 2167
CPPE+ +G+ C+ +C +QP C T + TG + C +G G
Sbjct: 981 TCPPEN--CSGYCTCS---HCLEQPGCGWC------TDPSNTG--KGKCIEGSYKGPVKM 1027
Query: 2168 PDHC--------------------RCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCR 2207
P R ++ F+ +C C+CN HS+C + C C
Sbjct: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFI--HCPA-CQCNGHSKCIN---QSICEKCE 1081
Query: 2208 NHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHIC 2246
N T G HCE C+ F G GG C+PC C G++ +C
Sbjct: 1082 NLTTGKHCETCISGFYGDPTNGGKCQPCK--CNGHASLC 1118
Score = 97.1 bits (240), Expect = 2e-19
Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 27/190 (14%)
Query: 870 RGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS 929
R A S ++C C+ R C DC + SS+C WC + C AY+A +P G C W
Sbjct: 920 RPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTM 979
Query: 930 VHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPL----GGGNCSLW 985
P +C G+ TC CL+ CGWC + N G+C++G + GP+ + +
Sbjct: 980 STCPP--ENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFY 1037
Query: 986 VGEGLGLPVALP---ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC-------HC 1035
L + L W++ CP +C+ + C+N + +C HC
Sbjct: 1038 PQPLLNSSMCLEDSRYNWSFIHCP--------ACQCNGHSKCINQSICEKCENLTTGKHC 1089
Query: 1036 Q---RGYQGD 1042
+ G+ GD
Sbjct: 1090 ETCISGFYGD 1099
Score = 83.6 bits (205), Expect = 3e-15
Identities = 77/292 (26%), Positives = 112/292 (38%), Gaps = 88/292 (30%)
Query: 931 HSEPRCRS-CDGFLTCHECLQ-SHECGWCGNEDNPTLGRCLQGD-FSGPLGGGNCSLWVG 987
HS +CR+ C C +C S EC WC N + +C+ + + G C W
Sbjct: 924 HSAKQCRTPCALRTACGDCTSGSSECMWCSN-----MKQCVDSNAYVASFPFGQCMEW-- 976
Query: 988 EGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC 1047
+ + CP + C TC SHC
Sbjct: 977 ------------YTMSTCPPEN--------CSGYCTC--------------------SHC 996
Query: 1048 NRTCLEDCGHGVCSGPPDF---TCVCDLGWTSDLPPPTPAPGP---PAP-----RCSRD- 1095
LE G G C+ P + C+ + + + P+ AP P P C D
Sbjct: 997 ----LEQPGCGWCTDPSNTGKGKCI-EGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDS 1051
Query: 1096 -----------CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
C C+ HS C + C++C++ T G+HCE C G +G+ T C+PC
Sbjct: 1052 RYNWSFIHCPACQCNGHSKCINQS--ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPC 1109
Query: 1145 QCNGHGDPRRGHCDNLSGLCFCQDH-TEGAHCQLC--SPGYYGDPRAGGSCF 1193
+CNGH C+ +G CFC +G CQLC Y G+P G+C+
Sbjct: 1110 KCNGHA----SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP-LRGTCY 1156
Score = 78.6 bits (192), Expect = 8e-14
Identities = 67/276 (24%), Positives = 97/276 (35%), Gaps = 68/276 (24%)
Query: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027
TC + +V P S C TPC L C C G C+W S+++QC+
Sbjct: 908 TCINPLNGSVCERPANHSAK-QCRTPCALRTACGDCTS------GSSECMWCSNMKQCVD 960
Query: 2028 PSYLPLRCMAGGCGRLLR----GPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRC 2083
+ G C PE+CS C C+ CL +P CGWC G G+C
Sbjct: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCT----CSHCLEQPGCGWCTDPSNTGKGKC 1016
Query: 2084 MEGGLSGP------------------RDGLTCGRPGASWAFLSCPPEDECANGHHDC-NE 2124
+EG GP + +W+F+ C P +C NGH C N+
Sbjct: 1017 IEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHC-PACQC-NGHSKCINQ 1074
Query: 2125 T--QNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNC 2182
+ + C + G C + C++G +P + G C
Sbjct: 1075 SICEKCENLTTGKHC--------------------ETCISGFYGDPTN--------GGKC 1106
Query: 2183 STECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQC 2218
C+CN H+ C KG C+ C
Sbjct: 1107 Q-PCKCNGHASLCNTNT-GKCFCTTKGVKGDECQLC 1140
Score = 67.4 bits (163), Expect = 2e-10
Identities = 108/449 (24%), Positives = 162/449 (36%), Gaps = 105/449 (23%)
Query: 834 CEEHRDCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRL 887
C++H DC++CT + C W + +CS G+ ++ E CP C+++
Sbjct: 704 CDQHTDCYSCTANTNDCHWCNDHCVPRNHSCS---EGQISIFRYENCPKDNPMYYCNKKT 760
Query: 888 TCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCR-GW--------------DDSVHS 932
+C C A C W C P C GW ++ ++
Sbjct: 761 SCRSC-ALDQNCQWEPRNQECIAL-------PENICGIGWHLVGNSCLKITTAKENYDNA 812
Query: 933 EPRCRSCDGF---LTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEG 989
+ CR+ + LT + ++ + + ++ + + G L N S W E
Sbjct: 813 KLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVG-LRKINVSYWCWED 871
Query: 990 LGLPVALPARWAYARCPDVDECRL---GLARCHPRATCLNTPLSYECHCQRGYQGDGISH 1046
+ +W + D C + R ATC+N PL+ C+R
Sbjct: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCIN-PLNGSV-CERP-ANHSAKQ 928
Query: 1047 CN-----RTCLEDCGHGV-----CSGPPDFTCVCDLGWTSDLPPP------TPAPGPPAP 1090
C RT DC G CS CV + + P T + PP
Sbjct: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQ--CVDSNAYVASFPFGQCMEWYTMSTCPP-E 985
Query: 1091 RCSRDCGCSFHSHCRKR-GPGFCDECQDWTWGEHCERCRPGSF------------GN--- 1134
CS C C SHC ++ G G+C + + G +C GS+ GN
Sbjct: 986 NCSGYCTC---SHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYP 1038
Query: 1135 ---------ATGSR------GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCS 1179
SR C CQCNGH C N S C++ T G HC+ C
Sbjct: 1039 QPLLNSSMCLEDSRYNWSFIHCPACQCNGH-----SKCINQSICEKCENLTTGKHCETCI 1093
Query: 1180 PGYYGDPRAGGSCFR-ECGGRALLTNVSS 1207
G+YGDP GG C +C G A L N ++
Sbjct: 1094 SGFYGDPTNGGKCQPCKCNGHASLCNTNT 1122
Score = 62.8 bits (151), Expect = 5e-09
Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 37/205 (18%)
Query: 2181 NCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL--PLFVGSAVGGGTCRPCHAF 2238
NCS C C+ E G G C N KG E P+ + S G P
Sbjct: 986 NCSGYCTCSHCLEQPGCG---WCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042
Query: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE--DEAVCVNCQNNSYGEKC 2296
NS +C+ E +Y+ G S+ ++++C C+N + G+ C
Sbjct: 1043 ---NSSMCL----------EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089
Query: 2297 ESCLQGYF---LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCY 2353
E+C+ G++ GKC C+CNGHA C NT TG C ++ + D
Sbjct: 1090 ETCISGFYGDPTNGGKCQPCKCNGHASLC------------NTNTGKCFCTTKGVKGD-- 1135
Query: 2354 KYQCAKCRESFHGSPLGGQQCYRLI 2378
+ Q + + G+PL G Y L+
Sbjct: 1136 ECQLCEVENRYQGNPLRGTCYYTLL 1160
Score = 35.4 bits (80), Expect = 0.79
Identities = 12/37 (32%), Positives = 19/37 (51%)
Query: 763 PGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWC 799
P G + ++ + +C+ Y +C CL GCGWC
Sbjct: 969 PFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 213 bits (542), Expect = 2e-54
Identities = 159/536 (29%), Positives = 239/536 (44%), Gaps = 49/536 (9%)
Query: 32 GQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDG 91
G R L + GFVTDG GNY C WLIE P + L F TEC++D+L+VYDG
Sbjct: 133 GGRFRLTGSSGFVTDGPGNYKYKTKCTWLIEG-QPNRIMRLRFNHFATECSWDHLYVYDG 191
Query: 92 DSPRGPLLASLSGSTRP--------PPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCP 143
DS PL+A+ SG P P + A+SG LLH FSDA YNL GFN ++ F +CP
Sbjct: 192 DSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCP 251
Query: 144 GGCQSHGQCQPPG-----VCACEPGWGGPDCGLQECSAYCG--SHGTC-ASPLGPCRCEP 195
C G+C+ C C W G C + C+ CG G C +S + C C
Sbjct: 252 NNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCGFPHRGICNSSDVRGCSCFS 311
Query: 196 GFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGAAGAFLSPPG-LLAVFGGQDLNNAL 254
+ G C + + NQ +W R+ + ++ A G ++ V GG N++
Sbjct: 312 DWQGPGCSVPVPANQ--SFW----TREEYSNLKLPRASHKAVVNGNIMWVVGGYMFNHSD 365
Query: 255 GDLVL-YNFSANTWESWDLS-PAPAARHSHVAVAWAGSLVLMGGEL-ADGSLTNDVWAFS 311
++VL Y+ ++ W + S R+ H + + + GG++ + G++TN++ F
Sbjct: 366 YNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFH 425
Query: 312 PLGRGHWELLAPPASSSSGPPGLAGHAAALVDD-VWLYVSGGRTPHDLFSSGLFRFRLDS 370
+ W LL P A G + H L + V + V G P + S + + LD
Sbjct: 426 -IHNESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDK 484
Query: 371 TSGGYWEQVIPAGGRPPAATGHSMVFHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDR 430
+ W + G GHS V+ +RAL VHGG++ +A + + VD
Sbjct: 485 NT---WSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDT 541
Query: 431 HVWTTLKGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEE---KCYEDGIFFYHLG 487
+WT LK R HTA ++ M+V+GGN H KC+ Y +
Sbjct: 542 QMWTILKDSRFF-----RYLHTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIA 596
Query: 488 CHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPRGDLMAY 543
C +W P R+ H +AVL S + V GG++ D++ +
Sbjct: 597 CDRW--------SVLPRPDLHHDVNRFGH-SAVLHNSTMYVFGGFNSLLLSDILVF 643
Score = 153 bits (386), Expect = 3e-36
Identities = 268/1179 (22%), Positives = 414/1179 (35%), Gaps = 237/1179 (20%)
Query: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL 1201
RPC NG G C+ +G C C G CQ CGGR
Sbjct: 103 RPC-VNG------GRCNPGTGQCVCPAGWVGEQCQ------------------HCGGRFR 137
Query: 1202 LTNVSSVALGSRRVGGLLPPGGGAARAGPG----LSYCVWVVSATEELQPCAPGTLCPPL 1257
LT S G GPG + C W++ P + +
Sbjct: 138 LTGSS-----------------GFVTDGPGNYKYKTKCTWLIEGQ-------PNRI---M 170
Query: 1258 TLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCG---QRRDRPLTVQ--- 1311
L F+ +T C+ ++ +DG + L+AAF G RD TV
Sbjct: 171 RLRFN-HFATECSWDHLYVYDGDSIYAP---------LVAAFSGLIVPERDGNETVPEVV 220
Query: 1312 ALSGLLVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQ 1370
A SG +LH+ ++ + + GFN + C P +C EC + + C C +
Sbjct: 221 ATSGYALLHFFSDAAYNLTGFNITYSFDMC----PNNCSGRGECKISNSSDTVE-CECSE 275
Query: 1371 GWAGPHCRMALCPENCNAHTGAGTCNQS-LGVCICAEGFGGPDCATKLDGGQLVWETLMD 1429
W G C + C +NC G CN S + C C + GP C+ + Q W
Sbjct: 276 NWKGEACDIPHCTDNCG-FPHRGICNSSDVRGCSCFSDWQGPGCSVPVPANQSFWTREEY 334
Query: 1430 SRLSADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGA 1489
S L AS +V+G +W+ GG + Y ++ R W +
Sbjct: 335 SNLKLPRASH------KAVVNGN--IMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSV 386
Query: 1490 EDGGPGPSPRSFHAAAYVPAGRGAMYLLGGL--TAGGVTRDFWVLNLTTLQWRQEKAPQT 1547
+ R H+ A + +Y+ GG + G VT + V ++ W P+
Sbjct: 387 NN----VVVRYGHSLALY---KDKIYMYGGKIDSTGNVTNELRVFHIHNESWVL-LTPKA 438
Query: 1548 VELPAVAGHT---LTARRG-LSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPT 1603
E AV GH+ +T + G + +L++ G+ P G+ + EY L TW G
Sbjct: 439 KEQYAVVGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQ 498
Query: 1604 GLYGHSAVYHEATDSLYVFGGFR-FHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRM 1662
G YGHS+VY T +LYV GG++ F + +LY + W++L S+ +
Sbjct: 499 GGYGHSSVYDHRTRALYVHGGYKAFSANKYRLADDLYRYDVDTQMWTILKDSRFFRYLHT 558
Query: 1663 RNVRGSSRGL--GQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLF 1720
+ + + G + S G + + L P L R
Sbjct: 559 AVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPR--PDLHHDVNRFG 616
Query: 1721 HASALLGDTMVVLGGRSDPDEFSSDVLLY-QVNCNAWLLPDLTRSASVGPPMEESVAHAV 1779
H++ L TM V GG + SD+L++ C+A +A G V
Sbjct: 617 HSAVLHNSTMYVFGGFNSL--LLSDILVFTSEQCDAHRSEAACLAAGPG-------IRCV 667
Query: 1780 AAVGSRLYISGGFGGVALGRLLAL------TLPPDPCRLLSSPEACN-QSGACTWCHGAC 1832
GS IS L TL D C + +C + C WC+ C
Sbjct: 668 WNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHC 727
Query: 1833 LSGDQAHRLGCGGSPCSPMPRSPEE-----CRRLRTCSECLARHPRTLQPGDGEASTPRC 1887
+ + H G P++ C + +C C +P + E
Sbjct: 728 VPRN--HSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWEPRNQE------ 779
Query: 1888 KWCTNCPEGAC-IGRN---GSCTSENDCRIN--QREVFWAGNCSEAACGAADCEQCTREG 1941
C PE C IG + SC + N ++F + + A T +
Sbjct: 780 --CIALPENICGIGWHLVGNSCLKITTAKENYDNAKLFCRNHNALLA-------SLTTQK 830
Query: 1942 KCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCT 2001
K + + R ++ + +S W +NVS E P +
Sbjct: 831 KVEFVLKQLRIMQSSQSMSKLTLTPWVGLRK--INVSYWCWEDMSPFT--------NSLL 880
Query: 2002 SCLDSKGADGGWQHCVWSSSLQQCLSPSYL-PLRCMAGGCGRLLR-GPESCSLGCAQATQ 2059
+ S+ +D G+ + S + + + + PL C R + C CA T
Sbjct: 881 QWMPSEPSDAGFCGILSEPSTRGLKAATCINPLN--GSVCERPANHSAKQCRTPCALRTA 938
Query: 2060 CALCLR-RPHCGWC----------AWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLS 2108
C C C WC A+ G+CME W +S
Sbjct: 939 CGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCME------------------WYTMS 980
Query: 2109 -CPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVE 2167
CPPE+ +G+ C+ +C +QP C T + TG + C +G G
Sbjct: 981 TCPPEN--CSGYCTCS---HCLEQPGCGWC------TDPSNTG--KGKCIEGSYKGPVKM 1027
Query: 2168 PDHC--------------------RCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCR 2207
P R ++ F+ +C C+CN HS+C + C C
Sbjct: 1028 PSQAPTGNFYPQPLLNSSMCLEDSRYNWSFI--HCPA-CQCNGHSKCIN---QSICEKCE 1081
Query: 2208 NHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHIC 2246
N T G HCE C+ F G GG C+PC C G++ +C
Sbjct: 1082 NLTTGKHCETCISGFYGDPTNGGKCQPCK--CNGHASLC 1118
Score = 97.1 bits (240), Expect = 2e-19
Identities = 53/190 (27%), Positives = 83/190 (43%), Gaps = 27/190 (14%)
Query: 870 RGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS 929
R A S ++C C+ R C DC + SS+C WC + C AY+A +P G C W
Sbjct: 920 RPANHSAKQCRTPCALRTACGDCTSGSSECMWCSNMKQCVDSNAYVASFPFGQCMEWYTM 979
Query: 930 VHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPL----GGGNCSLW 985
P +C G+ TC CL+ CGWC + N G+C++G + GP+ + +
Sbjct: 980 STCPP--ENCSGYCTCSHCLEQPGCGWCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFY 1037
Query: 986 VGEGLGLPVALP---ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC-------HC 1035
L + L W++ CP +C+ + C+N + +C HC
Sbjct: 1038 PQPLLNSSMCLEDSRYNWSFIHCP--------ACQCNGHSKCINQSICEKCENLTTGKHC 1089
Query: 1036 Q---RGYQGD 1042
+ G+ GD
Sbjct: 1090 ETCISGFYGD 1099
Score = 83.6 bits (205), Expect = 3e-15
Identities = 77/292 (26%), Positives = 112/292 (38%), Gaps = 88/292 (30%)
Query: 931 HSEPRCRS-CDGFLTCHECLQ-SHECGWCGNEDNPTLGRCLQGD-FSGPLGGGNCSLWVG 987
HS +CR+ C C +C S EC WC N + +C+ + + G C W
Sbjct: 924 HSAKQCRTPCALRTACGDCTSGSSECMWCSN-----MKQCVDSNAYVASFPFGQCMEW-- 976
Query: 988 EGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC 1047
+ + CP + C TC SHC
Sbjct: 977 ------------YTMSTCPPEN--------CSGYCTC--------------------SHC 996
Query: 1048 NRTCLEDCGHGVCSGPPDF---TCVCDLGWTSDLPPPTPAPGP---PAP-----RCSRD- 1095
LE G G C+ P + C+ + + + P+ AP P P C D
Sbjct: 997 ----LEQPGCGWCTDPSNTGKGKCI-EGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDS 1051
Query: 1096 -----------CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
C C+ HS C + C++C++ T G+HCE C G +G+ T C+PC
Sbjct: 1052 RYNWSFIHCPACQCNGHSKCINQS--ICEKCENLTTGKHCETCISGFYGDPTNGGKCQPC 1109
Query: 1145 QCNGHGDPRRGHCDNLSGLCFCQDH-TEGAHCQLC--SPGYYGDPRAGGSCF 1193
+CNGH C+ +G CFC +G CQLC Y G+P G+C+
Sbjct: 1110 KCNGHA----SLCNTNTGKCFCTTKGVKGDECQLCEVENRYQGNP-LRGTCY 1156
Score = 78.6 bits (192), Expect = 8e-14
Identities = 67/276 (24%), Positives = 97/276 (35%), Gaps = 68/276 (24%)
Query: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027
TC + +V P S C TPC L C C G C+W S+++QC+
Sbjct: 908 TCINPLNGSVCERPANHSAK-QCRTPCALRTACGDCTS------GSSECMWCSNMKQCVD 960
Query: 2028 PSYLPLRCMAGGCGRLLR----GPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRC 2083
+ G C PE+CS C C+ CL +P CGWC G G+C
Sbjct: 961 SNAYVASFPFGQCMEWYTMSTCPPENCSGYCT----CSHCLEQPGCGWCTDPSNTGKGKC 1016
Query: 2084 MEGGLSGP------------------RDGLTCGRPGASWAFLSCPPEDECANGHHDC-NE 2124
+EG GP + +W+F+ C P +C NGH C N+
Sbjct: 1017 IEGSYKGPVKMPSQAPTGNFYPQPLLNSSMCLEDSRYNWSFIHC-PACQC-NGHSKCINQ 1074
Query: 2125 T--QNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNC 2182
+ + C + G C + C++G +P + G C
Sbjct: 1075 SICEKCENLTTGKHC--------------------ETCISGFYGDPTN--------GGKC 1106
Query: 2183 STECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQC 2218
C+CN H+ C KG C+ C
Sbjct: 1107 Q-PCKCNGHASLCNTNT-GKCFCTTKGVKGDECQLC 1140
Score = 67.4 bits (163), Expect = 2e-10
Identities = 108/449 (24%), Positives = 162/449 (36%), Gaps = 105/449 (23%)
Query: 834 CEEHRDCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRL 887
C++H DC++CT + C W + +CS G+ ++ E CP C+++
Sbjct: 704 CDQHTDCYSCTANTNDCHWCNDHCVPRNHSCS---EGQISIFRYENCPKDNPMYYCNKKT 760
Query: 888 TCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCR-GW--------------DDSVHS 932
+C C A C W C P C GW ++ ++
Sbjct: 761 SCRSC-ALDQNCQWEPRNQECIAL-------PENICGIGWHLVGNSCLKITTAKENYDNA 812
Query: 933 EPRCRSCDGF---LTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEG 989
+ CR+ + LT + ++ + + ++ + + G L N S W E
Sbjct: 813 KLFCRNHNALLASLTTQKKVEFVLKQLRIMQSSQSMSKLTLTPWVG-LRKINVSYWCWED 871
Query: 990 LGLPVALPARWAYARCPDVDECRL---GLARCHPRATCLNTPLSYECHCQRGYQGDGISH 1046
+ +W + D C + R ATC+N PL+ C+R
Sbjct: 872 MSPFTNSLLQWMPSEPSDAGFCGILSEPSTRGLKAATCIN-PLNGSV-CERP-ANHSAKQ 928
Query: 1047 CN-----RTCLEDCGHGV-----CSGPPDFTCVCDLGWTSDLPPP------TPAPGPPAP 1090
C RT DC G CS CV + + P T + PP
Sbjct: 929 CRTPCALRTACGDCTSGSSECMWCSNMKQ--CVDSNAYVASFPFGQCMEWYTMSTCPP-E 985
Query: 1091 RCSRDCGCSFHSHCRKR-GPGFCDECQDWTWGEHCERCRPGSF------------GN--- 1134
CS C C SHC ++ G G+C + + G +C GS+ GN
Sbjct: 986 NCSGYCTC---SHCLEQPGCGWCTDPSNTGKG----KCIEGSYKGPVKMPSQAPTGNFYP 1038
Query: 1135 ---------ATGSR------GCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCS 1179
SR C CQCNGH C N S C++ T G HC+ C
Sbjct: 1039 QPLLNSSMCLEDSRYNWSFIHCPACQCNGH-----SKCINQSICEKCENLTTGKHCETCI 1093
Query: 1180 PGYYGDPRAGGSCFR-ECGGRALLTNVSS 1207
G+YGDP GG C +C G A L N ++
Sbjct: 1094 SGFYGDPTNGGKCQPCKCNGHASLCNTNT 1122
Score = 62.8 bits (151), Expect = 5e-09
Identities = 55/205 (26%), Positives = 83/205 (40%), Gaps = 37/205 (18%)
Query: 2181 NCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL--PLFVGSAVGGGTCRPCHAF 2238
NCS C C+ E G G C N KG E P+ + S G P
Sbjct: 986 NCSGYCTCSHCLEQPGCG---WCTDPSNTGKGKCIEGSYKGPVKMPSQAPTGNFYPQPLL 1042
Query: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE--DEAVCVNCQNNSYGEKC 2296
NS +C+ E +Y+ G S+ ++++C C+N + G+ C
Sbjct: 1043 ---NSSMCL----------EDSRYNWSFIHCPACQCNGHSKCINQSICEKCENLTTGKHC 1089
Query: 2297 ESCLQGYF---LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCY 2353
E+C+ G++ GKC C+CNGHA C NT TG C ++ + D
Sbjct: 1090 ETCISGFYGDPTNGGKCQPCKCNGHASLC------------NTNTGKCFCTTKGVKGD-- 1135
Query: 2354 KYQCAKCRESFHGSPLGGQQCYRLI 2378
+ Q + + G+PL G Y L+
Sbjct: 1136 ECQLCEVENRYQGNPLRGTCYYTLL 1160
Score = 60.1 bits (144), Expect = 3e-08
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 48/177 (27%)
Query: 2572 FRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFA 2631
F Q +DL FF FFSCF L + ++WK KQ+ + + + L+EM +MASRPFA
Sbjct: 1270 FSQHSNFMDLVQFFVTFFSCFLSLLLVAAVVWKIKQSCWASRRREQLLREMQQMASRPFA 1329
Query: 2632 KVTVCFPPDPTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPA 2691
V V D PP +
Sbjct: 1330 SVNVALETDEE-------------------------------------------PPDLIG 1346
Query: 2692 TTAGLRAGPITLEPTEDGMAGVATLLLQLPGG-----PHAPNGACLGSALVTLRHRL 2743
+ PI LEP A V ++ ++LP G P +G + SALV + ++
Sbjct: 1347 GSIKTVPKPIALEPCFGNKAAVLSVFVRLPRGLGGIPPPGQSGLAVASALVDISQQM 1403
Score = 35.4 bits (80), Expect = 0.79
Identities = 12/37 (32%), Positives = 19/37 (51%)
Query: 763 PGGSEISFFFLEPYRSSSCTSYSSCLGCLADQGCGWC 799
P G + ++ + +C+ Y +C CL GCGWC
Sbjct: 969 PFGQCMEWYTMSTCPPENCSGYCTCSHCLEQPGCGWC 1005
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 100 bits (250), Expect = 2e-20
Identities = 114/426 (26%), Positives = 148/426 (34%), Gaps = 72/426 (16%)
Query: 1035 CQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSR 1094
C Y+ G C C ++C HG C P C C GW D APG P+C +
Sbjct: 91 CHGFYESRGF--CVPLCAQECVHGRCVAPNQ--CQCVPGWRGDDCSSECAPGMWGPQCDK 146
Query: 1095 DCGCSFHSHCRKRGPGFCDECQDWTWGEHC-ERCRPGSFGNATGSRGCRPCQCNGHGDPR 1153
C C +S C + G C C +C + C PG +G A R CQC HG P
Sbjct: 147 PCSCGNNSSCDPKS-GVCS-CPSGLQPPNCLQPCTPGYYGPACQFR----CQC--HGAP- 197
Query: 1154 RGHCDNLSGLCFCQDHTEGAHCQL-CSPGYYG----------------DPRAGGSCFREC 1196
CD +G CFC G C + CS G G P+ SC
Sbjct: 198 ---CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW 254
Query: 1197 GGRALLTNVSSVALGSR-------RVGGLLPPGGGAARAGPGLS--YCVWVVSATEELQP 1247
G G GGL G R PG + C Q
Sbjct: 255 MGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQD 314
Query: 1248 CAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRP 1307
CA C P F + + C + TG +DR F G P
Sbjct: 315 CAETCDCAPDARCFPANGACLCEHGF------------TGDRCTDRLCPDGFYGLSCQAP 362
Query: 1308 LTVQALSGLLV--LHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA---AG 1362
T L ++ E + W S + GPG + C+ G A
Sbjct: 363 CTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGC---QEHCLCLHGGVCQAT 419
Query: 1363 AGLCRCPQGWAGPHCRMALCPE-----NCNAH---TGAGTCNQSLGVCICAEGFGGPDCA 1414
+GLC+C G+ GPHC +LCP NC+A A C+ G C+C EG+ +C+
Sbjct: 420 SGLCQCAPGYTGPHC-ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS 478
Query: 1415 TKLDGG 1420
G
Sbjct: 479 VPCPPG 484
Score = 98.6 bits (244), Expect = 8e-20
Identities = 175/726 (24%), Positives = 230/726 (31%), Gaps = 205/726 (28%)
Query: 776 YRSSSCTSYSS--CLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLC-- 831
+R C+S + G D+ C C +++C + G C L P C
Sbjct: 126 WRGDDCSSECAPGMWGPQCDKPCS-CGNNSSCDPKSGVCSCPSG--------LQPPNCLQ 176
Query: 832 --------PLCEEHRDCHACTQDP-----FCEWHQSTSRKGDAACSRRGRG--------- 869
P C+ CH DP FC + T D +CS+ G
Sbjct: 177 PCTPGYYGPACQFRCQCHGAPCDPQTGACFCP-AERTGPSCDVSCSQGTSGFFCPSTHSC 235
Query: 870 --RGALKSPE---ECPP-----LCSQRLTCEDCL--ANSSQCAWCQSTHTCFLFAAYLAR 917
G ++P+ CPP +CS L C + N SQ C + C F
Sbjct: 236 QNGGVFQTPQGSCSCPPGWMGTICS--LPCPEGFHGPNCSQECRCHNGGLCDRFT----- 288
Query: 918 YPHGGCRGWDDSVHSEPRCRS-CDGFLTCHECLQSHEC----------GWCGNEDNPTLG 966
G CR ++ RCR C +C ++ +C G C E T
Sbjct: 289 ---GQCRCAPG--YTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGD 343
Query: 967 RCLQGDFSGPLGGGNC----------SLWVGEGLGLPVALPARWAYARCPDVDECRLGLA 1016
RC G +C SL G LP WA C +
Sbjct: 344 RCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPG-WAGLHCNESCPQDTHGP 402
Query: 1017 RCHPRATCLNTPL----SYECHCQRGYQGDGISHCNRTCLED-----------CGHGVCS 1061
C CL+ + S C C GY G HC C D C + +
Sbjct: 403 GCQEHCLCLHGGVCQATSGLCQCAPGYTGP---HCASLCPPDTYGVNCSARCSCENAIAC 459
Query: 1062 GPPDFTCVCDLGWT-SDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTW 1120
P D CVC GW + P P PG C+ C C+ + C + G C W
Sbjct: 460 SPIDGECVCKEGWQRGNCSVPCP-PGTWGFSCNASCQCAHEAVCSPQ-TGACTCTPGWH- 516
Query: 1121 GEHCER-CRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQL-C 1178
G HC+ C G FG SR C C+ H D CD + G C CQ GA C L C
Sbjct: 517 GAHCQLPCPKGQFGEGCASR----CDCD-HSDG----CDPVHGRCQCQAGWMGARCHLSC 567
Query: 1179 SPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWV 1238
G +G +C C + + GG P G PG
Sbjct: 568 PEGLWGV-----NCSNTC---------------TCKNGGTCLPENGNCVCAPGFRG---- 603
Query: 1239 VSATEELQPCAPGTLCPPLTL---TFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSL 1295
S QP G C P +F S+ C
Sbjct: 604 PSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCYC------------------------ 639
Query: 1296 IAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECV 1355
+A + G +P WG N + + +C GG C
Sbjct: 640 LAGWTGPDCSQPCP----------------PGHWGENCAQ-TCQCHHGGT--------CH 674
Query: 1356 PQDGAAGAGLCRCPQGWAGPHCRMALCP-----ENCNAHTGAG---TCNQSLGVCICAEG 1407
PQDG+ C CP GW G HC + CP NC+ G C+ G C+C G
Sbjct: 675 PQDGS-----CICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPG 728
Query: 1408 FGGPDC 1413
G C
Sbjct: 729 HSGAPC 734
Score = 86.7 bits (213), Expect = 3e-16
Identities = 124/479 (25%), Positives = 160/479 (33%), Gaps = 123/479 (25%)
Query: 1011 CRLGLARCHPRATCLNTPL-----SYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPD 1065
C+ A C P+ P S + C +G G C T C +G P
Sbjct: 191 CQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSG---FFCPST--HSCQNGGVFQTPQ 245
Query: 1066 FTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHC- 1124
+C C GW + G P CS++C C C R G C C G+ C
Sbjct: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLC-DRFTGQC-RCAPGYTGDRCR 303
Query: 1125 ERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHC--QLCSPGY 1182
E C G FG C+ D R C +G C C+ G C +LC G+
Sbjct: 304 EECPVGRFGQDCAET------CDCAPDAR---CFPANGACLCEHGFTGDRCTDRLCPDGF 354
Query: 1183 YG-DPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARA---------GPGL 1232
YG +A +C RE N L PG GPG
Sbjct: 355 YGLSCQAPCTCDREHSLSCHPMNGECSCL----------PGWAGLHCNESCPQDTHGPGC 404
Query: 1233 S-YCVW----VVSATEELQPCAPG-------TLCPPLTLTFSPDSSTPCTLSYVLAFDGF 1280
+C+ V AT L CAPG +LCPP T + + S C+ +A
Sbjct: 405 QEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDT--YGVNCSARCSCENAIACSPI 462
Query: 1281 PRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGF--NAS---- 1334
D + QR + +V G +WGF NAS
Sbjct: 463 -----------DGECVCKEGWQRGN--CSVPCPPG------------TWGFSCNASCQCA 497
Query: 1335 --------VGSARCGSGGPGS-----CPVPQ---------ECVPQDGAAGA-GLCRCPQG 1371
G+ C G G+ CP Q +C DG G C+C G
Sbjct: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAG 557
Query: 1372 WAGPHCRMALCPEN---------CNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQ 1421
W G C ++ CPE C G GTC G C+CA GF GP C G+
Sbjct: 558 WMGARCHLS-CPEGLWGVNCSNTCTCKNG-GTCLPENGNCVCAPGFRGPSCQRSCQPGR 614
Score = 63.5 bits (153), Expect = 3e-09
Identities = 114/449 (25%), Positives = 144/449 (32%), Gaps = 116/449 (25%)
Query: 1990 CPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQ--QCLSPS----YLP---LRCMAGG- 2039
C PC SC ++ D C S LQ CL P Y P RC G
Sbjct: 144 CDKPC-------SCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGA 196
Query: 2040 ----------CGRLLRGPESCSLGCAQATQCALCLRRPHC----------GWCA----WG 2075
C GP SC + C+Q T C C G C+ W
Sbjct: 197 PCDPQTGACFCPAERTGP-SCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWM 255
Query: 2076 GQDGGGRCMEGGLSGPR--DGLTCGRPGASWAFLS---CPP-------EDECANGH--HD 2121
G C EG GP C G F C P +EC G D
Sbjct: 256 GTICSLPCPEG-FHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQD 314
Query: 2122 CNETQNCHDQ----PHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEP--------- 2168
C ET +C P C C+ G+T D T +C G SC P
Sbjct: 315 CAETCDCAPDARCFPANGACLCEHGFTGDRCTDR---LCPDGFYGLSCQAPCTCDREHSL 371
Query: 2169 ------DHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCE------ 2216
C C G+ G +C+ C + H G G ++HCL G C+
Sbjct: 372 SCHPMNGECSCLPGWAGLHCNESCPQDTH----GPGCQEHCLCLH----GGVCQATSGLC 423
Query: 2217 QCLPLFVGSAVGGGTCRP------CHAFCRGNSHICIS--RKELQMSKGEPKKYSLDPEE 2268
QC P + G C P C A C + I S E +G + P
Sbjct: 424 QCAPGYTGPHC-ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
Query: 2269 IENW----VTEGPSEDEAVC------VNCQNNSYGEKCE-SCLQGYFLLDGKCTKCQCNG 2317
W EAVC C +G C+ C +G F +G ++C C+
Sbjct: 483 PGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQF-GEGCASRCDCD- 540
Query: 2318 HADTCNEQDGTGCPCQNNTETGTCQGSSP 2346
H+D C+ G C CQ C S P
Sbjct: 541 HSDGCDPVHGR-CQCQAGWMGARCHLSCP 568
Score = 60.8 bits (146), Expect = 2e-08
Identities = 152/667 (22%), Positives = 202/667 (30%), Gaps = 173/667 (25%)
Query: 1805 LPPDPC-RLLSSPEACNQSGAC-TWCHGACLSGDQAHRLGCGG----SPCSPMPRSPEEC 1858
LP +PC R P C Q + + D RL C S +P +EC
Sbjct: 50 LPSEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQEC 109
Query: 1859 RRLRTCSECLARHPRTLQPG-DGEASTPRCK---WCTNCPEGACIGRNGSCTSEN----- 1909
R C+A + PG G+ + C W C + G N SC ++
Sbjct: 110 VHGR----CVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSC 165
Query: 1910 -------DCRINQREVFWAGNCS-EAACGAADCEQCTREGKCMWTRQFKRTGETRRILSV 1961
+C ++ C C A C+ T G C + RTG + +
Sbjct: 166 PSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQT--GACFCPAE--RTGPSCDVSCS 221
Query: 1962 QPTYDWTCFS-HSLLN----VSPMPVESSPP--------LPCPTPCHLLPNCTS------ 2002
Q T + C S HS N +P S PP LPCP H PNC+
Sbjct: 222 QGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHG-PNCSQECRCHN 280
Query: 2003 ------------CLDSKGADGGWQHCVWSSSLQQCLSPSYLP--LRCMA--GGC------ 2040
C D + C Q C RC G C
Sbjct: 281 GGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGF 340
Query: 2041 ---------------GRLLRGPESC----SLGCAQATQCALCL---RRPHCGWCAWGGQD 2078
G + P +C SL C CL HC
Sbjct: 341 TGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTH 400
Query: 2079 GGG-----RCMEGGLSGPRDGLTCGRPGASWAFLS--CPPEDECANGHHDCNETQNCHDQ 2131
G G C+ GG+ GL PG + + CPP+ N C+
Sbjct: 401 GPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACS 460
Query: 2132 PHGYECSCKTGYTMDNMTGLCRP-----------VCAQGCV----NGSCV-----EPDHC 2171
P EC CK G+ N + C P CA V G+C HC
Sbjct: 461 PIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC 520
Query: 2172 R--CHFGFVGRNCSTECRCNRHSECAGVGARDHC----------LLCRNHTKGSHCEQCL 2219
+ C G G C++ C C+ C V R C L C G +C
Sbjct: 521 QLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC 580
Query: 2220 PLFVGSAVGGGTCRPCHAFCRGNSHICIS--RKELQMSKGEPKKYS--LDPEEIENWVTE 2275
+ GGTC P + C +C R +P +Y P + N
Sbjct: 581 -----TCKNGGTCLPENGNC-----VCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC 630
Query: 2276 GPSEDEAVCV----------NCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQ 2325
PS C+ C +GE C CQC+ H TC+ Q
Sbjct: 631 HPSNGTCYCLAGWTGPDCSQPCPPGHWGENC-------------AQTCQCH-HGGTCHPQ 676
Query: 2326 DGTGCPC 2332
DG+ C C
Sbjct: 677 DGS-CIC 682
Score = 59.3 bits (142), Expect = 5e-08
Identities = 66/281 (23%), Positives = 101/281 (35%), Gaps = 42/281 (14%)
Query: 2150 GLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTEC-------RCNRHSECAGVGARD- 2201
G C P+CAQ CV+G CV P+ C+C G+ G +CS+EC +C++ C + D
Sbjct: 99 GFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDP 158
Query: 2202 --HCLLCRNHTKGSHCEQ-CLPLFVGSA------VGGGTCRPCHAFCRGNSHICISRKEL 2252
C + + +C Q C P + G A G C P C + ++
Sbjct: 159 KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV 218
Query: 2253 QMSKGEPKKYSLDPEEIENWVTEGPSEDEAVC----------VNCQNNSYGEKCES---C 2299
S+G + +N + C + C +G C C
Sbjct: 219 SCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRC 278
Query: 2300 LQGYFL--LDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQC 2357
G G+C +C D C E+ G Q+ ET C +P R C+
Sbjct: 279 HNGGLCDRFTGQC-RCAPGYTGDRCREECPVGRFGQDCAETCDC---APDAR--CFPANG 332
Query: 2358 A-KCRESFHGSPLGGQQC---YRLISVEQECCLDPTSQTNC 2394
A C F G + C + +S + C D +C
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSC 373
Score = 53.1 bits (126), Expect = 4e-06
Identities = 30/74 (40%), Positives = 33/74 (44%), Gaps = 13/74 (17%)
Query: 142 CPG--GCQSHGQCQPP-GVCACEPGWGGPDCGLQ--------ECSAYCGSH--GTCASPL 188
CP CQ+ G Q P G C+C PGW G C L CS C H G C
Sbjct: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFT 288
Query: 189 GPCRCEPGFLGRAC 202
G CRC PG+ G C
Sbjct: 289 GQCRCAPGYTGDRC 302
Score = 49.3 bits (116), Expect = 5e-05
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 11/71 (15%)
Query: 143 PGGCQSHGQCQPP-GVCACEPGWGGPDCGL--------QECSAYCGSH--GTCASPLGPC 191
P C +H C P G C C GW GPDC + C+ C H GTC G C
Sbjct: 621 PCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSC 680
Query: 192 RCEPGFLGRAC 202
C G+ G C
Sbjct: 681 ICPLGWTGHHC 691
Score = 48.9 bits (115), Expect = 7e-05
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 26/90 (28%)
Query: 137 FRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECS-----------AYCGSHGTCA 185
F LC C HG+C P C C PGW G DC EC+ CG++ +C
Sbjct: 100 FCVPLCAQECV-HGRCVAPNQCQCVPGWRGDDCS-SECAPGMWGPQCDKPCSCGNNSSCD 157
Query: 186 SPLGPCR-------------CEPGFLGRAC 202
G C C PG+ G AC
Sbjct: 158 PKSGVCSCPSGLQPPNCLQPCTPGYYGPAC 187
Score = 47.0 bits (110), Expect = 3e-04
Identities = 107/464 (23%), Positives = 147/464 (31%), Gaps = 113/464 (24%)
Query: 1819 CNQSGACTWCHGAC-----LSGDQAHR---LGCGGSPCSPMPRSPEECRRLRTCSECLAR 1870
C+ G C G C +GD+ +G G C+ + R CL
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCE 337
Query: 1871 HPRTLQPGDGEASTPRCKWCTNCPEGAC-IGRNGSCTSENDCRINQREVF--------WA 1921
H T G+ T R CP+G + CT + + ++ + WA
Sbjct: 338 HGFT-----GDRCTDRL-----CPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWA 387
Query: 1922 G-NCSEAA---CGAADCEQ---CTREGKCMWTRQFKR-----TGETRRILSVQPTYDWTC 1969
G +C+E+ C++ C G C T + TG L TY C
Sbjct: 388 GLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNC 447
Query: 1970 FSH----SLLNVSPMPVE---------SSPPLPCPT-----PCHLLPNCTS---CLDSKG 2008
+ + + SP+ E + +PCP C+ C C G
Sbjct: 448 SARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTG 507
Query: 2009 A---DGGWQ--HCVWSSSLQQ----CLS-----------PSYLPLRCMAGGCGRLLRGPE 2048
A GW HC Q C S P + +C AG G
Sbjct: 508 ACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA------ 561
Query: 2049 SCSLGCAQATQCALCLRRPHC---GWCAWGGQDGGGRCMEGGLSGPRDGLTC--GRPGAS 2103
C L C + C C G C + G G GP +C GR G
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCL---PENGNCVCAPGFRGPSCQRSCQPGRYGKR 618
Query: 2104 WAFLSCPPEDECANGHHDCNETQNCHDQPHGYECS--CKTGYTMDNMTGLCRPVCAQGCV 2161
C C H N T C G +CS C G+ +N C+ C G
Sbjct: 619 CVPCKCANHSFC----HPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQ--CHHGGT 672
Query: 2162 ----NGSCVEP-----DHCR--CHFGFVGRNCSTECRCNRHSEC 2194
+GSC+ P HC C G G NCS C+C +C
Sbjct: 673 CHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKC 716
Score = 44.3 bits (103), Expect = 0.002
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 11/70 (15%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDCGL--------QECSAYCG-SHGTCASPL-GPCRCE 194
C C P G C C PGW G C L + C++ C H P+ G C+C+
Sbjct: 496 CAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQ 555
Query: 195 PGFLGRACDL 204
G++G C L
Sbjct: 556 AGWMGARCHL 565
Score = 44.3 bits (103), Expect = 0.002
Identities = 25/68 (36%), Positives = 28/68 (41%), Gaps = 11/68 (16%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDCGLQ--------ECS--AYCGSHGTCASPLGPCRCE 194
C C P G C C+ GW G C L CS C + GTC G C C
Sbjct: 539 CDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCA 598
Query: 195 PGFLGRAC 202
PGF G +C
Sbjct: 599 PGFRGPSC 606
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 14/76 (18%)
Query: 142 CPGGCQSHGQ-CQPP-GVCACEPGWGGPDCGLQECSA-----YCGSHGTCAS------PL 188
C CQ HG C P G C C GP C + CS +C S +C + P
Sbjct: 187 CQFRCQCHGAPCDPQTGACFCPAERTGPSCDVS-CSQGTSGFFCPSTHSCQNGGVFQTPQ 245
Query: 189 GPCRCEPGFLGRACDL 204
G C C PG++G C L
Sbjct: 246 GSCSCPPGWMGTICSL 261
Score = 43.1 bits (100), Expect = 0.004
Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 16/84 (19%)
Query: 132 GFNASFRFSLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQ----------ECSAYCGS 180
G N S R S C++ C P G C C+ GW +C + S C
Sbjct: 444 GVNCSARCS-----CENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAH 498
Query: 181 HGTCASPLGPCRCEPGFLGRACDL 204
C+ G C C PG+ G C L
Sbjct: 499 EAVCSPQTGACTCTPGWHGAHCQL 522
Score = 42.7 bits (99), Expect = 0.005
Identities = 28/87 (32%), Positives = 33/87 (37%), Gaps = 26/87 (29%)
Query: 141 LCPGG-----CQSHGQCQPP---------GVCACEPGWGGPDC-----------GLQECS 175
LCP G CQ+ C G C+C PGW G C G QE
Sbjct: 349 LCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQE-H 407
Query: 176 AYCGSHGTCASPLGPCRCEPGFLGRAC 202
C G C + G C+C PG+ G C
Sbjct: 408 CLCLHGGVCQATSGLCQCAPGYTGPHC 434
Score = 42.7 bits (99), Expect = 0.005
Identities = 27/81 (33%), Positives = 30/81 (37%), Gaps = 15/81 (18%)
Query: 142 CPGGCQSH--GQCQPP-GVCACEPGWGGPDCGLQECS-----------AYCGSHGTCASP 187
C CQ H G C P G C C GW G C L+ C CG C
Sbjct: 661 CAQTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGCPLGTFGANCSQPCQCGPGEKCHPE 719
Query: 188 LGPCRCEPGFLGRACDLHLWE 208
G C C PG G C + + E
Sbjct: 720 TGACVCPPGHSGAPCRIGIQE 740
Score = 37.0 bits (84), Expect = 0.27
Identities = 22/69 (31%), Positives = 26/69 (37%), Gaps = 13/69 (18%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDCGLQEC-----------SAYCGSHGTCASPLGPCRC 193
C + G C G C C PG+ G C +EC + C C G C C
Sbjct: 278 CHNGGLCDRFTGQCRCAPGYTGDRCR-EECPVGRFGQDCAETCDCAPDARCFPANGACLC 336
Query: 194 EPGFLGRAC 202
E GF G C
Sbjct: 337 EHGFTGDRC 345
Score = 33.9 bits (76), Expect = 2.3
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 16/73 (21%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDC----------GLQECSAYCG---SHGTCASPL-GP 190
C +C P G C CE G+ G C GL C A C H P+ G
Sbjct: 321 CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS-CQAPCTCDREHSLSCHPMNGE 379
Query: 191 CRCEPGFLGRACD 203
C C PG+ G C+
Sbjct: 380 CSCLPGWAGLHCN 392
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 99.0 bits (245), Expect = 6e-20
Identities = 157/654 (24%), Positives = 201/654 (30%), Gaps = 191/654 (29%)
Query: 871 GALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSV 930
G +S + C PLC+ E+C+ C S TC + GC DS
Sbjct: 91 GYYESGDFCIPLCT-----EECVHGR-----CVSPDTCHCEPGWGGPDCSSGC----DSD 136
Query: 931 HSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGL 990
H P C + C +C C NP G C+ + G C G
Sbjct: 137 HWGPHCSN-----RC-QCQNGALC-------NPITGACV---CAAGFRGWRCEELCAPGT 180
Query: 991 -GLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQG-------- 1041
G LP +CR G A C PRA EC C GY G
Sbjct: 181 HGKGCQLPC-----------QCRHG-ASCDPRAG--------ECLCAPGYTGVYCEELCP 220
Query: 1042 --DGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCS 1099
+HC C C +G C C GWT + PG CS+DC C
Sbjct: 221 PGSHGAHCELRC--PCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCH 278
Query: 1100 FHSHC-RKRGPGFC------DECQD--------WTWGEHCE--------------RCRPG 1130
C G C D CQ+ + +HC+ C PG
Sbjct: 279 HGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPG 338
Query: 1131 SFGNATGSRGC----------RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHC-QLCS 1179
G R C PC C+ C ++G C CQ G HC + C
Sbjct: 339 YKGPRCQERLCPEGLHGPGCTLPCPCDADNTI---SCHPVTGACTCQPGWSGHHCNESCP 395
Query: 1180 PGYYGDP-------RAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPP---------GG 1223
GYYGD + G C GG G P G
Sbjct: 396 VGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG 455
Query: 1224 GAARAGPGLSYC----------------VWVVSATEELQPCAPGTLCPPLTLTFSPDSST 1267
G G C W ++ E CA G C P+ D S
Sbjct: 456 GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC-TCANGAACSPI------DGSC 508
Query: 1268 PCTLSYVLAFDGFPRFL-DTGVVQSDRSLIAAFCGQRRD-------RPLTVQ--ALSGLL 1317
CT P +L DT + C + D P+T L+G
Sbjct: 509 SCT----------PGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWT 558
Query: 1318 VLHWEAN-GSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPH 1376
+ ++ WG N SV S C +GG C P+DG+ C C G+ GP
Sbjct: 559 GIRCDSTCPPGRWGPNCSV-SCSCENGG--------SCSPEDGS-----CECAPGFRGPL 604
Query: 1377 CRMALCPENCNAH----------TGAGTCNQSLGVCICAEGFGGPDCATKLDGG 1420
C+ +CP H + C+ G+C C GF G C GG
Sbjct: 605 CQ-RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGG 657
Score = 97.8 bits (242), Expect = 1e-19
Identities = 153/625 (24%), Positives = 202/625 (32%), Gaps = 161/625 (25%)
Query: 834 CEEHRDCH----------ACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLC 883
C +H DCH AC CE R + C G G CP
Sbjct: 314 CSQHCDCHNGGQCSPTTGACE----CEPGYKGPRCQERLCPEGLHGPGCTLP---CPCDA 366
Query: 884 SQRLTCEDCL-ANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGF 942
++C A + Q W S H C + Y GC+ + + C S G
Sbjct: 367 DNTISCHPVTGACTCQPGW--SGHHCN--ESCPVGYYGDGCQ-LPCTCQNGADCHSITGG 421
Query: 943 LTC------HECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVAL 996
TC C S G G + ++ C G P+ G +C+ G GL L
Sbjct: 422 CTCAPGFMGEVCAVSCAAGTYGPNCS-SICSCNNGGTCSPVDG-SCTCKEG-WQGLDCTL 478
Query: 997 PARWAYARCPDVDECRLGLARCHPRATCLN----TPLSYECHCQRGYQGDGIS------- 1045
P CP GL C+ TC N +P+ C C G+ GD
Sbjct: 479 P-------CPSGT---WGL-NCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGT 527
Query: 1046 ---HCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHS 1102
+C+ C DC H P C C GWT T PG P CS C C
Sbjct: 528 FGLNCSEHC--DCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585
Query: 1103 HCRKRGPGFCDECQDWTWGEHCER-CRPGSFGNATGSRGC-RPCQCNGHGDPRRGHCDNL 1160
C G C EC G C+R C PG +G+ GC +PC H C ++
Sbjct: 586 SCSPE-DGSC-ECAPGFRGPLCQRICPPGFYGH-----GCAQPCPLCVHSS---RPCHHI 635
Query: 1161 SGLCFCQDHTEGAHC-QLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLL 1219
SG+C C GA C Q+C+ GY+G C + C S G
Sbjct: 636 SGICECLPGFSGALCNQVCAGGYFGQ-----DCAQLC---------------SCANNGTC 675
Query: 1220 PPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDG 1279
P G+ + PG W+ + Q C PG P S + C+
Sbjct: 676 SPIDGSCQCFPG-----WI--GKDCSQACPPGFWGPACFHACSCHNGASCS--------- 719
Query: 1280 FPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSAR 1339
+ G FC QR A+
Sbjct: 720 ----AEDGACHCTPGWTGLFCTQR---------------------------CPAAFFGKD 748
Query: 1340 CGSGGPGSCPVPQECVPQDGAAG---AGLCRCPQGWAGPHCRMAL--------CPENCNA 1388
CG + C Q+GA+ +G C C G+ G HC C + C
Sbjct: 749 CG----------RVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCEC 798
Query: 1389 HTGAGTCNQSLGVCICAEGFGGPDC 1413
+ TC+ G C C+ GF G C
Sbjct: 799 MNNS-TCDHVTGTCYCSPGFKGIRC 822
Score = 87.0 bits (214), Expect = 2e-16
Identities = 163/660 (24%), Positives = 211/660 (31%), Gaps = 145/660 (21%)
Query: 799 CLTSATCHLRQGGAHCGDDGAGGSLLVLVP--TLCPLCEEHRDCHACTQDPFCEWHQSTS 856
C TCH G C G P T C + CH Q C+ H +
Sbjct: 234 CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ---CD-HVT-- 287
Query: 857 RKGDAACSRRGRGRGALKSPEECPP-----LCSQRLTCEDCLANSSQCAWCQSTHTCFLF 911
G C+ G + EECP CSQ C N QC+ +T C
Sbjct: 288 --GQCHCTAGYMGD---RCQEECPFGSFGFQCSQHCDCH----NGGQCS--PTTGACECE 336
Query: 912 AAYLARYPHGGCRGWDDSVHSEPRCR-----SCDGFLTCHECLQSHEC--GWCGNEDNPT 964
Y + P R + +H P C D ++CH + C GW G+ N
Sbjct: 337 PGY--KGPRCQERLCPEGLHG-PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNE- 392
Query: 965 LGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATC 1024
S P+G + G+G LP C + +C C TC
Sbjct: 393 ---------SCPVG------YYGDGCQLPCT---------CQNGADCHSITGGC----TC 424
Query: 1025 LNTPLSYEC--HCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTS-DLPPP 1081
+ C C G G +C+ C C +G P D +C C GW D P
Sbjct: 425 APGFMGEVCAVSCAAGTYGP---NCSSIC--SCNNGGTCSPVDGSCTCKEGWQGLDCTLP 479
Query: 1082 TPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCER-CRPGSFGNATGSRG 1140
P+ G C+ C C+ + C G C W G+ CE C G+FG
Sbjct: 480 CPS-GTWGLNCNESCTCANGAACSPID-GSCSCTPGWL-GDTCELPCPDGTFGLNCSEH- 535
Query: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQ-LCSPGYYGDPRAGGSCFRECGGR 1199
C C+ H D CD ++G C C G C C PG +G P SC E GG
Sbjct: 536 ---CDCS-HADG----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCENGGS 586
Query: 1200 ALLTNVSSVALGSRR---VGGLLPPGGGAARAGPGLSYCVWV------VSATEELQPCAP 1250
+ S R + PPG CV +S E P
Sbjct: 587 CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFS 646
Query: 1251 GTLCPPLTLT--FSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPL 1308
G LC + F D + C+ A +G +D G Q I C Q
Sbjct: 647 GALCNQVCAGGYFGQDCAQLCSC----ANNGTCSPID-GSCQCFPGWIGKDCSQ------ 695
Query: 1309 TVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRC 1368
A WG A + C +G C +DGA C C
Sbjct: 696 --------------ACPPGFWG-PACFHACSCHNGA--------SCSAEDGA-----CHC 727
Query: 1369 PQGWAGPHCRMAL--------CPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGG 1420
GW G C C C GA +C+ G C C GF G C + G
Sbjct: 728 TPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGA-SCDHISGKCTCRTGFTGQHCEQRCAPG 786
Score = 66.6 bits (161), Expect = 3e-10
Identities = 121/481 (25%), Positives = 161/481 (33%), Gaps = 83/481 (17%)
Query: 1807 PDPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLRTCSE 1866
P PC ++ +GACT C G H C S P+ + C+ TC
Sbjct: 361 PCPCDADNTISCHPVTGACT-----CQPGWSGHH--CNES--CPVGYYGDGCQLPCTCQN 411
Query: 1867 CLARHPRT----LQPGD-GEAST---------PRCKWCTNCPEGA-CIGRNGSCTSEN-- 1909
H T PG GE P C +C G C +GSCT +
Sbjct: 412 GADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGW 471
Query: 1910 ---DCRINQREVFWAGNCSEAACGAADCEQCTR-EGKCMWTRQFKRTGETRRILSVQPTY 1965
DC + W NC+E+ C A+ C+ +G C T + G+T + T+
Sbjct: 472 QGLDCTLPCPSGTWGLNCNES-CTCANGAACSPIDGSCSCTPGW--LGDTCELPCPDGTF 528
Query: 1966 DWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSC-LDSKGADGGW-QHCVWSSSLQ 2023
C H + + P C L T DS G W +C S S +
Sbjct: 529 GLNCSEHCDCS------HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE 582
Query: 2024 Q--CLSPSYLPLRCMAGGCGRLLRG---PESCSLGCAQATQCALCLRRPH-----CGWCA 2073
SP C G G L + P GCAQ C LC+ G C
Sbjct: 583 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQP--CPLCVHSSRPCHHISGICE 640
Query: 2074 WGGQDGGGRCME---GGLSGPRDGLTCGRPGASWAFLSCPPED---ECANGHHDCNETQN 2127
G C + GG G C +C P D +C G + +Q
Sbjct: 641 CLPGFSGALCNQVCAGGYFGQDCAQLCSCANNG----TCSPIDGSCQCFPGWIGKDCSQA 696
Query: 2128 CHDQPHG----YECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCS 2183
C G + CSC G + G C C G C + RC F G++C
Sbjct: 697 CPPGFWGPACFHACSCHNGASCSAEDGACH--CTPGWTGLFCTQ----RCPAAFFGKDCG 750
Query: 2184 TECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQ-CLPLFVGSAVGGGTCRPCHAFCRGN 2242
C+C + C + + CR G HCEQ C P G G + C C N
Sbjct: 751 RVCQCQNGASCDHISGK---CTCRTGFTGQHCEQRCAP----GTFGYGCQQLCE--CMNN 801
Query: 2243 S 2243
S
Sbjct: 802 S 802
Score = 63.2 bits (152), Expect = 4e-09
Identities = 102/391 (26%), Positives = 132/391 (33%), Gaps = 111/391 (28%)
Query: 2035 CMAGGCGRLLRGPESCSLG-----CAQATQC---ALCLRRPHCGWCAWGGQDGGGRCMEG 2086
C AG G R E C G C+Q C C P G C G RC E
Sbjct: 292 CTAGYMGD--RCQEECPFGSFGFQCSQHCDCHNGGQC--SPTTGACECEPGYKGPRCQER 347
Query: 2087 ----GLSGPRDGLTCGRPGASWAFLSCPPEDECA------NGHHDCNETQNCHDQPHGY- 2135
GL GP L C P + +SC P +GHH CNE+ C P GY
Sbjct: 348 LCPEGLHGPGCTLPC--PCDADNTISCHPVTGACTCQPGWSGHH-CNES--C---PVGYY 399
Query: 2136 ------ECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCN 2189
C+C+ G ++TG C CA G + C C G G NCS+ C CN
Sbjct: 400 GDGCQLPCTCQNGADCHSITGGC--TCAPGFMGEVCA----VSCAAGTYGPNCSSICSCN 453
Query: 2190 RHSECAGVGARDHC----------LLCRNHTKGSHC-EQCLPLFVGSAVGGGTCRPCHAF 2238
C+ V C L C + T G +C E C + G C P
Sbjct: 454 NGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC------TCANGAACSPIDGS 507
Query: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNN---SYGEK 2295
C S P + + E P D +NC + S+ +
Sbjct: 508 C-----------------------SCTPGWLGD-TCELPCPDGTFGLNCSEHCDCSHADG 543
Query: 2296 CE------SCLQGY--FLLDGKC----------TKCQCNGHADTCNEQDGTGCPCQNNTE 2337
C+ CL G+ D C C C + +C+ +DG+ C C
Sbjct: 544 CDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCE-NGGSCSPEDGS-CECAPGFR 601
Query: 2338 TGTCQGSSPSDRRDCYKYQCAK-CRESFHGS 2367
CQ P Y + CA+ C H S
Sbjct: 602 GPLCQRICPP---GFYGHGCAQPCPLCVHSS 629
Score = 58.9 bits (141), Expect = 7e-08
Identities = 44/127 (34%), Positives = 51/127 (40%), Gaps = 22/127 (17%)
Query: 134 NASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSH---------GTC 184
+ F LC C HG+C P C CEPGWGGPDC S + G H G
Sbjct: 95 SGDFCIPLCTEECV-HGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGAL 153
Query: 185 ASPL-GPCRCEPGFLGRACDLHLWENQGAGWWHNVSARDPAFSARIGA-----AGAFLSP 238
+P+ G C C GF G C E A H + P R GA AG L
Sbjct: 154 CNPITGACVCAAGFRGWRC-----EELCAPGTHGKGCQLPC-QCRHGASCDPRAGECLCA 207
Query: 239 PGLLAVF 245
PG V+
Sbjct: 208 PGYTGVY 214
Score = 58.5 bits (140), Expect = 9e-08
Identities = 83/342 (24%), Positives = 102/342 (29%), Gaps = 98/342 (28%)
Query: 2046 GPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGL-TCGRPGASW 2104
GP+ CS GC PHC +C G L P G C W
Sbjct: 126 GPD-CSSGCDSDHW------GPHCS--------NRCQCQNGALCNPITGACVCAAGFRGW 170
Query: 2105 AFLSCPPEDECANGHH--------DCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRP-- 2154
E+ CA G H C +C P EC C GYT LC P
Sbjct: 171 RC-----EELCAPGTHGKGCQLPCQCRHGASC--DPRAGECLCAPGYTGVYCEELCPPGS 223
Query: 2155 ------------------------VCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNR 2190
C G C +P C G G+NCS +C C+
Sbjct: 224 HGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQP----CPPGTFGQNCSQDCPCHH 279
Query: 2191 HSECAGVGARDHC-------------------LLCRNHTKGSHCEQCLPLFVGSAVGGGT 2231
+C V + HC C H + QC P G
Sbjct: 280 GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSP-----TTGACE 334
Query: 2232 CRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNS 2291
C P + R +C P P + +N ++ P CQ
Sbjct: 335 CEPGYKGPRCQERLC------PEGLHGPGCTLPCPCDADNTISCHPVTG---ACTCQPGW 385
Query: 2292 YGEKC-ESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPC 2332
G C ESC GY+ DG C C AD C+ G GC C
Sbjct: 386 SGHHCNESCPVGYY-GDGCQLPCTCQNGAD-CHSITG-GCTC 424
Score = 54.3 bits (129), Expect = 2e-06
Identities = 65/271 (23%), Positives = 86/271 (31%), Gaps = 70/271 (25%)
Query: 2152 CRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTEC-------RCNRHSEC---AGVGARD 2201
C P+C + CV+G CV PD C C G+ G +CS+ C C+ +C A
Sbjct: 99 CIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPIT 158
Query: 2202 HCLLCRNHTKGSHCEQ-CLPLFVGSAV-------GGGTCRP---------------CHAF 2238
+C +G CE+ C P G G +C P C
Sbjct: 159 GACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL 218
Query: 2239 CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVN-CQNNSYGEKCE 2297
C SH G + I P AVC C ++G+ C
Sbjct: 219 CPPGSHGAHCELRCPCQNGGTCHH------ITGECACPPGWTGAVCAQPCPPGTFGQNCS 272
Query: 2298 S---CLQGYFLLDGKCT----KCQCNG--HADTCNEQDGTG---------CPCQNNTE-- 2337
C G G+C +C C D C E+ G C C N +
Sbjct: 273 QDCPCHHG-----GQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCS 327
Query: 2338 --TGTCQGSSPSDRRDCYKYQCAKCRESFHG 2366
TG C+ C Q C E HG
Sbjct: 328 PTTGACECEPGYKGPRC---QERLCPEGLHG 355
Score = 53.5 bits (127), Expect = 3e-06
Identities = 43/151 (28%), Positives = 58/151 (38%), Gaps = 39/151 (25%)
Query: 132 GFNASFRFSLCPGGCQSHGQCQP--------------PGVCACEPGWGGPDCGL------ 171
GF +CP G HG QP G+C C PG+ G C
Sbjct: 599 GFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGY 658
Query: 172 --QECSAYCG--SHGTCASPLGPCRCEPGFLGR----ACDLHLWENQGAGWWH------- 216
Q+C+ C ++GTC+ G C+C PG++G+ AC W G +H
Sbjct: 659 FGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW---GPACFHACSCHNG 715
Query: 217 -NVSARDPAFSARIGAAGAFLSPPGLLAVFG 246
+ SA D A G G F + A FG
Sbjct: 716 ASCSAEDGACHCTPGWTGLFCTQRCPAAFFG 746
Score = 52.4 bits (124), Expect = 6e-06
Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 13/76 (17%)
Query: 140 SLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQ--------ECSAYCG-SHGTCASPL- 188
S+C C + G C P G C C+ GW G DC L C+ C ++G SP+
Sbjct: 448 SIC--SCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID 505
Query: 189 GPCRCEPGFLGRACDL 204
G C C PG+LG C+L
Sbjct: 506 GSCSCTPGWLGDTCEL 521
Score = 49.7 bits (117), Expect = 4e-05
Identities = 31/86 (36%), Positives = 37/86 (43%), Gaps = 21/86 (24%)
Query: 136 SFRFSLCPGGCQSH--GQCQPP-GVCACEPGWGGPDCGLQECSAYCGSHG---------- 182
SF F C C H GQC P G C CEPG+ GP C + C G HG
Sbjct: 309 SFGFQ-CSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPE--GLHGPGCTLPCPCD 365
Query: 183 -----TCASPLGPCRCEPGFLGRACD 203
+C G C C+PG+ G C+
Sbjct: 366 ADNTISCHPVTGACTCQPGWSGHHCN 391
Score = 48.5 bits (114), Expect = 9e-05
Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 11/72 (15%)
Query: 142 CPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQECSAY----------CGSHGTCASPLGP 190
CP + C P G C C+PGW G C Y C + C S G
Sbjct: 362 CPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG 421
Query: 191 CRCEPGFLGRAC 202
C C PGF+G C
Sbjct: 422 CTCAPGFMGEVC 433
Score = 47.8 bits (112), Expect = 2e-04
Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 13/76 (17%)
Query: 142 CPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQ--------ECSAYCGSH--GTCASPLGP 190
CP C GQC G C C G+ G C + +CS +C H G C+ G
Sbjct: 275 CP--CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA 332
Query: 191 CRCEPGFLGRACDLHL 206
C CEPG+ G C L
Sbjct: 333 CECEPGYKGPRCQERL 348
Score = 43.1 bits (100), Expect = 0.004
Identities = 28/88 (31%), Positives = 32/88 (36%), Gaps = 24/88 (27%)
Query: 140 SLCPGG-----------CQSHGQCQPP-GVCACEPGWGGPDCG------------LQECS 175
S CP G C++ G C P G C C PG+ GP C Q C
Sbjct: 564 STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 623
Query: 176 AYCGSHGTCASPLGPCRCEPGFLGRACD 203
S C G C C PGF G C+
Sbjct: 624 LCVHSSRPCHHISGICECLPGFSGALCN 651
Score = 42.4 bits (98), Expect = 0.006
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 11/73 (15%)
Query: 143 PGGCQSHGQCQP-PGVCACEPGWGGPDCGLQ--------ECSAYCGSH--GTCASPLGPC 191
P CQ+ C G C C PG+ G C + CS+ C + GTC+ G C
Sbjct: 406 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
Query: 192 RCEPGFLGRACDL 204
C+ G+ G C L
Sbjct: 466 TCKEGWQGLDCTL 478
Score = 42.4 bits (98), Expect = 0.006
Identities = 25/69 (36%), Positives = 30/69 (43%), Gaps = 11/69 (15%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDCGLQ--------ECSAYCG-SHGTCASPL-GPCRCE 194
C + C P G C+C PGW G C L CS +C SH P+ G C C
Sbjct: 495 CANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCL 554
Query: 195 PGFLGRACD 203
G+ G CD
Sbjct: 555 AGWTGIRCD 563
Score = 41.2 bits (95), Expect = 0.014
Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 11/71 (15%)
Query: 143 PGGCQSHGQCQP-PGVCACEPGWGGPDC----------GLQECSAYCGSHGTCASPLGPC 191
P C+ C P G C C PG+ G C E C + GTC G C
Sbjct: 188 PCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGEC 247
Query: 192 RCEPGFLGRAC 202
C PG+ G C
Sbjct: 248 ACPPGWTGAVC 258
Score = 40.8 bits (94), Expect = 0.019
Identities = 23/70 (32%), Positives = 28/70 (40%), Gaps = 13/70 (18%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDCGLQECS-----------AYCGSHGTCASPLGPCRC 193
CQ+ C G C C G+ G C Q C+ C ++ TC G C C
Sbjct: 755 CQNGASCDHISGKCTCRTGFTGQHCE-QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYC 813
Query: 194 EPGFLGRACD 203
PGF G CD
Sbjct: 814 SPGFKGIRCD 823
Score = 32.0 bits (71), Expect = 8.7
Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
Query: 1368 CPQGWAGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLD 1418
CP + + LC E C H G C S C C G+GGPDC++ D
Sbjct: 89 CPGYYESGDFCIPLCTEEC-VH---GRC-VSPDTCHCEPGWGGPDCSSGCD 134
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 94.7 bits (234), Expect = 1e-18
Identities = 132/553 (23%), Positives = 195/553 (35%), Gaps = 116/553 (20%)
Query: 1856 EECRRLRTC--SECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRI 1913
E C +TC S L R + GD C+ CT C GA R SC N C
Sbjct: 265 ENCHCEKTCQVSGLLYRDQDSWVDGD------HCRNCT-CKSGAVECRRMSCPPLN-CSP 316
Query: 1914 NQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHS 1973
+ V AG C C+ C KC++ K E +RIL+ C
Sbjct: 317 DSLPVHIAGQC---------CKVC--RPKCIYGG--KVLAEGQRILTKSCR---ECRGGV 360
Query: 1974 LLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGAD--------GGWQHCV-WSSSLQQ 2024
L+ ++ M PPL C H+LP C +G + G C W++
Sbjct: 361 LVKITEM----CPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATC 416
Query: 2025 CLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCM 2084
Y+ ++ + C + + C+ +C+ P C C+
Sbjct: 417 ECKSGYISVQGDSAYCEDI----DECAAKMHYCHANTVCVNLPGLYRCD---------CV 463
Query: 2085 EGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYT 2144
G + SC DEC +G H+C+E C + G+ C+CK GY
Sbjct: 464 PGYIRVDD--------------FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509
Query: 2145 MDNMTGLCRPVCAQGC-VNGSCVEPDHCRCHFGFVGRNCS---TEC-----RCNRHSECA 2195
+ +CR C +GC G+CV P+ C C GF G +C EC C+ HS C
Sbjct: 510 GNGT--ICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCV 567
Query: 2196 GVGARDHCLLCRN--HTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKE-L 2252
+ HC CR+ H G++ ++ G +C C +H C + +
Sbjct: 568 NLPGWYHC-ECRSGFHDDGTY-----------SLSGESCIDIDE-CALRTHTCWNDSACI 614
Query: 2253 QMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTK 2312
++ G + GPS C + G K Q + L + +C+
Sbjct: 615 NLAGG-----------FDCLCPSGPS-----CSGDCPHEGGLKHNG--QVWTLKEDRCSV 656
Query: 2313 CQCNGHADTCNEQDGTGCPCQN-NTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGG 2371
C C C T C CQN + + C C K S
Sbjct: 657 CSCKDGKIFCRR---TACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSC 713
Query: 2372 QQCYRLISVEQEC 2384
QQC R + E +C
Sbjct: 714 QQC-RCLEGEVDC 725
Score = 63.9 bits (154), Expect = 2e-09
Identities = 87/368 (23%), Positives = 127/368 (34%), Gaps = 65/368 (17%)
Query: 821 GSLLVLVPTLCP---------LCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRG 871
G +LV + +CP + E++ C C FC + G+ + + +
Sbjct: 358 GGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCA---EGPKCGENSECKNWNTKA 414
Query: 872 ALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCF-LFAAYLARYPHGGCRGWDDSV 930
+ + CED +++ +C + C L Y G R D S
Sbjct: 415 TCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSC 474
Query: 931 HSEPRCRS----CDGFLTCHECLQSHEC----GWCGNEDNPTLGRCLQGDFSGPLGGGNC 982
C S CD C +Q H C G+ GN T+ R + G GG C
Sbjct: 475 TEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNG---TICRAFCEE--GCRYGGTC 529
Query: 983 SLWVGEGLGLPVALPARWAYARCP-DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQG 1041
P+ + + C D+DEC G+ CH + C+N P Y C C+ G+
Sbjct: 530 VA------PNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHD 583
Query: 1042 DG-ISHCNRTC--LEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGC 1098
DG S +C +++C + D C+ G L P P CS DC
Sbjct: 584 DGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCL-------CPSGPSCSGDC-- 634
Query: 1099 SFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCD 1158
G Q WT E +RC S + G CR C+ C
Sbjct: 635 -------PHEGGLKHNGQVWTLKE--DRCSVCSCKD--GKIFCRRTACD---------CQ 674
Query: 1159 NLSGLCFC 1166
N S FC
Sbjct: 675 NPSADLFC 682
Score = 42.4 bits (98), Expect = 0.006
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 7/71 (9%)
Query: 134 NASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDC--GLQECS---AYCGSHGTCASPL 188
N + + C GC+ G C P C C G+ G C + ECS C +H C +
Sbjct: 511 NGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLP 570
Query: 189 G--PCRCEPGF 197
G C C GF
Sbjct: 571 GWYHCECRSGF 581
Score = 33.1 bits (74), Expect = 3.9
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 7/55 (12%)
Query: 1366 CRCPQGWAGPH--CRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLD 1418
C C G+ G CR A C E C GTC + C+C GF G C +D
Sbjct: 502 CTCKPGYVGNGTICR-AFCEEGCRY---GGTC-VAPNKCVCPSGFTGSHCEKDID 551
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 93.6 bits (231), Expect = 2e-18
Identities = 69/249 (27%), Positives = 98/249 (39%), Gaps = 58/249 (23%)
Query: 2122 CNETQN---CHDQPHGYEC-SCKTGYTMDNMTGLCRPV-CA-QGCVNGSCVEPDHCRCHF 2175
CN+T C G C +CK G+ ++ +GLC+P C+ G ++ C C+C
Sbjct: 254 CNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNSSGKCQCKV 313
Query: 2176 GFVGRNCST--------------ECRCN-RHSEC-AGVGARDHCLLCRNHTKGSHCEQCL 2219
G +G C C+CN R + C A GA CL C+ ++KG+HCE+C
Sbjct: 314 GVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGA---CLNCQENSKGNHCEECK 370
Query: 2220 PLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE 2279
F S C C ++ C K L+PE
Sbjct: 371 EGFYQSPDATKECLRCPCSAVTSTGSC-----------SIKSSELEPE------------ 407
Query: 2280 DEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHAD------TCNEQDGTGCPCQ 2333
C C++ G C C GY+ D C KCQC+GH D C + G C
Sbjct: 408 ----CDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPESGECINCL 463
Query: 2334 NNTETGTCQ 2342
+NT C+
Sbjct: 464 HNTTGFWCE 472
Score = 77.0 bits (188), Expect = 2e-13
Identities = 55/168 (32%), Positives = 71/168 (42%), Gaps = 47/168 (27%)
Query: 1032 ECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPR 1091
+C C+ GYQG HC E C G L +TS L P
Sbjct: 260 QCECRPGYQG---LHC-----ETCKEGFY-----------LNYTSGLCQP---------- 290
Query: 1092 CSRDCGCSFHSH----CRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCN 1147
C CS H C G C +C+ G C+RC+ G +G + GC PCQCN
Sbjct: 291 ----CDCSPHGALSIPCNSSGK--C-QCKVGVIGSICDRCQDGYYGFS--KNGCLPCQCN 341
Query: 1148 GHGDPRRGHCDNLSGLCF-CQDHTEGAHCQLCSPGYYGDPRAGGSCFR 1194
R CD L+G C CQ++++G HC+ C G+Y P A C R
Sbjct: 342 N----RSASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLR 385
Score = 55.1 bits (131), Expect = 1e-06
Identities = 31/87 (35%), Positives = 43/87 (49%), Gaps = 8/87 (9%)
Query: 1112 CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGH--CDNLSGLCF-CQD 1168
CD+C+D G +C +C G + CR CQC+GH DP + C SG C C
Sbjct: 408 CDQCKDGYIGPNCNKCENGYY---NFDSICRKCQCHGHVDPVKTPKICKPESGECINCLH 464
Query: 1169 HTEGAHCQLCSPGYYGDPRAGGSCFRE 1195
+T G C+ C GY D G+C ++
Sbjct: 465 NTTGFWCENCLEGYVHD--LEGNCIKK 489
Score = 52.4 bits (124), Expect = 6e-06
Identities = 40/172 (23%), Positives = 57/172 (33%), Gaps = 50/172 (29%)
Query: 2206 CRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLD 2265
CR +G HCE C F + G C+PC G I
Sbjct: 263 CRPGYQGLHCETCKEGFYLNYTSG-LCQPCDCSPHGALSI-------------------- 301
Query: 2266 PEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-LLDGKCTKCQCNGHADTCNE 2324
P C C+ G C+ C GY+ C CQCN + +C+
Sbjct: 302 -----------PCNSSGKC-QCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDA 349
Query: 2325 QDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYR 2376
G CQ N++ C+ +C+E F+ SP ++C R
Sbjct: 350 LTGACLNCQENSKGNHCE----------------ECKEGFYQSPDATKECLR 385
Score = 38.1 bits (87), Expect = 0.12
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 1144 CQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
C C+ G C+ +G C C+ +G HC+ C G+Y
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY 280
Score = 36.6 bits (83), Expect = 0.35
Identities = 23/68 (33%), Positives = 28/68 (41%), Gaps = 19/68 (27%)
Query: 153 QPPGVCACEPGWGGPDC-------------GL-QECSAYCGSHGTCASPL---GPCRCEP 195
Q G C C PG+ G C GL Q C C HG + P G C+C+
Sbjct: 256 QTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCD--CSPHGALSIPCNSSGKCQCKV 313
Query: 196 GFLGRACD 203
G +G CD
Sbjct: 314 GVIGSICD 321
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 93.2 bits (230), Expect = 3e-18
Identities = 166/686 (24%), Positives = 222/686 (32%), Gaps = 207/686 (30%)
Query: 786 SCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDCH---A 842
SC + D C ATCH R +C CP+ + CH A
Sbjct: 310 SCSQNIDDCATAVCFHGATCHDRVASFYCA---------------CPMGKTGLLCHLDDA 354
Query: 843 CTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRLTCEDCLANSS 897
C +P E DA C A+ + CPP C Q + ++C ++
Sbjct: 355 CVSNPCHE---------DAICDTNPVNGRAICT---CPPGFTGGACDQDV--DECSIGAN 400
Query: 898 QCAW---CQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRS---------CDGFLTC 945
C C +T FL RG+ + PRC + C TC
Sbjct: 401 PCEHLGRCVNTQGSFLCQCG---------RGY-----TGPRCETDVNECLSGPCRNQATC 446
Query: 946 HECLQSHEC----GWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWA 1001
+ + C G+ G + C S + GG C V G P+ ++
Sbjct: 447 LDRIGQFTCICMAGFTGTYCEVDIDECQS---SPCVNGGVCKDRVN---GFSCTCPSGFS 500
Query: 1002 YARCP-DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLED-CGHGV 1059
+ C DVDEC C A C++ P YEC C G++G C D C HG
Sbjct: 501 GSTCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR 558
Query: 1060 C-SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDW 1118
C G F+C C APG RC DEC+
Sbjct: 559 CVDGIASFSCAC-------------APGYTGTRCESQV----------------DECRS- 588
Query: 1119 TWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSG--LCFCQDHTEGAHCQ 1176
+PC+ HG G C +L LC C T G +C+
Sbjct: 589 -----------------------QPCR---HG----GKCLDLVDKYLCRCPSGTTGVNCE 618
Query: 1177 L---------CSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAAR 1227
+ C+ G D C + G L NV S G GG+
Sbjct: 619 VNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGE-----GGSCV 673
Query: 1228 AGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFS-PDSSTPCTLSYVLAFD---GFPRF 1283
G C+ C PG+L PPL L S P + PC S+ + +D GF
Sbjct: 674 DGENGFRCL-----------CPPGSL-PPLCLPPSHPCAHEPC--SHGICYDAPGGFRCV 719
Query: 1284 LDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSG 1343
+ G + G R + L A S GF+ + C G
Sbjct: 720 CEPG-----------WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCT-----CPPG 763
Query: 1344 GPG-SCPVPQECVPQDGAAGAG---------LCRCPQGWAGPHCRMAL--C--PENCNAH 1389
G C + C P G +C CPQGW GP C+ + C P C H
Sbjct: 764 VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPH 823
Query: 1390 TGAGTCNQSLG--VCICAEGFGGPDC 1413
G C G C C G+ GP C
Sbjct: 824 ---GICTNLAGSFSCTCHGGYTGPSC 846
Score = 84.7 bits (208), Expect = 1e-15
Identities = 193/774 (24%), Positives = 245/774 (31%), Gaps = 190/774 (24%)
Query: 774 EPYRSSSCTSYSSCLGCLADQG-----CGWCLTSATCHLR--QGGAHCGDDGAGGSLLVL 826
EP C C+ + G C L C + + G C DG G
Sbjct: 702 EPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG------ 755
Query: 827 VPTLCPLCEEHRDCHA---CTQDPFCEWHQSTSRKGD---AACSRRGRGRGALKSPEEC- 879
CP + R C CT +P + S G +C + +G + +EC
Sbjct: 756 FHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECA 815
Query: 880 -PPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWD-DSVHSEPRCR 937
P C C + LA S C TC HGG G D ++
Sbjct: 816 GPAPCGPHGICTN-LAGSFSC-------TC-----------HGGYTGPSCDQDINDCDPN 856
Query: 938 SCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALP 997
C +C + + S C P R + S P G G C+ V P
Sbjct: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVAS---FTCTCP 913
Query: 998 ARWAYARCP-DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLE-DC 1055
+ C D+ +C + C TC++ S+ C C+ GY G H CL C
Sbjct: 914 PGYGGFHCEQDLPDC--SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
Query: 1056 GHG-VCSGP-PDFTCVCD-----------LGWTSDLP----------------PP----- 1081
HG VCS P F C C + W S P PP
Sbjct: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGR 1031
Query: 1082 -TPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCER-------- 1126
P + G C+ G ++ C + G HCE+
Sbjct: 1032 LCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ 1091
Query: 1127 -CRPGSFGNATGSRGCRPCQC----NG----------------HGDPRRGHCDNLSG--L 1163
C+ G G G G C+C NG HG G C +L L
Sbjct: 1092 PCQHG--GTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHG----GSCIDLVARYL 1145
Query: 1164 CFCQDHTEGAHCQL----CSPGYYGD--PRA--GGSCFRECGG--------------RAL 1201
C C T G C++ C PG D PR G+C GG A
Sbjct: 1146 CSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEAD 1205
Query: 1202 LTNVSSVALGSRRVGGLLP-PGGG---AARAGPGLSYCVWVVSATEELQPCAPGTLCPPL 1257
+ S A + L PGGG AG C V+S E QPC G C P
Sbjct: 1206 INECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES-QPCQHGGQCRPS 1264
Query: 1258 TLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSL---IAAFCGQ--RRDRPLTVQA 1312
P T F G PR V +S R L + C Q R R
Sbjct: 1265 P---GPGGGLTFTCHCAQPFWG-PRC--ERVARSCRELQCPVGVPCQQTPRGPRCACPPG 1318
Query: 1313 LSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSC-PVPQECVPQDGAAGAGLCRCPQG 1371
LSG + GS NAS +A C GG SC P P A C C QG
Sbjct: 1319 LSGPSCRSFP--GSPPGASNASCAAAPCLHGG--SCRPAP--------LAPFFRCACAQG 1366
Query: 1372 WAGPHCRM-ALCPE----------NCNAHTGAGTCNQSLGVCICAEGFGGPDCA 1414
W GP C A PE C A G C++ C G+ G DC+
Sbjct: 1367 WTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGC--GWDGGDCS 1418
Score = 77.4 bits (189), Expect = 2e-13
Identities = 117/454 (25%), Positives = 146/454 (32%), Gaps = 104/454 (22%)
Query: 777 RSSSCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCG---DDGAGGSLLVLVPTLCPL 833
RS C CL L D+ C + T G +C DD A P +
Sbjct: 587 RSQPCRHGGKCLD-LVDKYLCRCPSGTT------GVNCEVNIDDCASN------PCTFGV 633
Query: 834 CEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCL 893
C + + + C P + A S G G + LC CL
Sbjct: 634 CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL 693
Query: 894 ANSSQCAWCQSTHTCFLFAAYLARYPHGGCR-----GWD----------DSVHSEPRCR- 937
S CA +H A GG R GW D+ S+P CR
Sbjct: 694 PPSHPCAHEPCSHGICYDAP-------GGFRCVCEPGWSGPRCSQSLARDACESQP-CRA 745
Query: 938 ----SCDGF---LTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGL 990
S DG TC +Q +C L C GG C G+
Sbjct: 746 GGTCSSDGMGFHCTCPPGVQGRQC--------ELLSPCTPNPCEH---GGRCESAPGQ-- 792
Query: 991 GLPV-ALPARWAYARCP-DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCN 1048
LPV + P W RC DVDEC G A C P C N S+ C C GY G C+
Sbjct: 793 -LPVCSCPQGWQGPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGYTGPS---CD 847
Query: 1049 RTCLEDCGHGVC-------SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFH 1101
+ + DC C G F+C C PG PRC+RD
Sbjct: 848 QD-INDCDPNPCLNGGSCQDGVGSFSCSC-------------LPGFAGPRCARDVDECLS 893
Query: 1102 SHCRKRGPGFCDE--------CQDWTWGEHCER----CRPGS-FGNATGSRGCRPCQCNG 1148
+ C GPG C + C G HCE+ C P S F T G C
Sbjct: 894 NPC---GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
Query: 1149 HGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGY 1182
HC + + C + G C PG+
Sbjct: 951 RPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Score = 68.2 bits (165), Expect = 1e-10
Identities = 154/728 (21%), Positives = 210/728 (28%), Gaps = 184/728 (25%)
Query: 780 SCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRD 839
SCT S G C S C + GA C D G LC+ + D
Sbjct: 492 SCTCPSGFSGSTCQLDVDEC-ASTPC---RNGAKCVDQPDGYECRCAEGFEGTLCDRNVD 547
Query: 840 CHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQC 899
C+ DP C + +C+ C+ T C + +C
Sbjct: 548 --DCSPDP-CHHGRCVDGIASFSCA------------------CAPGYTGTRCESQVDEC 586
Query: 900 AW--CQSTHTCF-LFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGW 956
C+ C L YL R P G G + V+ + + F C + + ++C
Sbjct: 587 RSQPCRHGGKCLDLVDKYLCRCP-SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDC-- 643
Query: 957 CGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLA 1016
Q F+GPL C++ + E P
Sbjct: 644 -----------VCQPGFTGPL----CNVEINECASSP----------------------- 665
Query: 1017 RCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCL-EDCGHGVC-SGPPDFTCVCDLGW 1074
C +C++ + C C G + C E C HG+C P F CVC+ GW
Sbjct: 666 -CGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGW 724
Query: 1075 TSDLPPPTPAPGPPAPRCSRDCG--------CSFHSHCRKRGPGFCDECQDWTWGEHCER 1126
+ PRCS+ C C G GF C G CE
Sbjct: 725 SG-------------PRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL 771
Query: 1127 ---CRPGSF---GNATGSRGCRP-CQC-NGHGDPR----------------RGHCDNLSG 1162
C P G + G P C C G PR G C NL+G
Sbjct: 772 LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAG 831
Query: 1163 LCFCQDH--------------------TEGAHCQ--------LCSPGYYGDPRAGGSCFR 1194
C H G CQ C PG+ AG C R
Sbjct: 832 SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF-----AGPRCAR 886
Query: 1195 E--------CGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYC---------VW 1237
+ CG +V+S PPG G L C
Sbjct: 887 DVDECLSNPCGPGTCTDHVASFTC-------TCPPGYGGFHCEQDLPDCSPSSCFNGGTC 939
Query: 1238 VVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVL--AFDGFPRFLDTGVVQSDRSL 1295
V C PG P S PC V A GF
Sbjct: 940 VDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT 999
Query: 1296 IAAFCGQRRDRPLTVQALSGLLVL---HWEANGSSSWGFNASVGSARCGSGGPGSCPVPQ 1352
+ +C ++ + +G L W +A+ G C
Sbjct: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
Query: 1353 ECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSLG--VCICAEGFGG 1410
+CV +D + C CP+G G HC + P GTC +G +C C G+ G
Sbjct: 1060 QCVDEDSSH---YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNG 1116
Query: 1411 PDCATKLD 1418
+C +D
Sbjct: 1117 DNCEDDVD 1124
Score = 60.8 bits (146), Expect = 2e-08
Identities = 51/179 (28%), Positives = 65/179 (36%), Gaps = 24/179 (13%)
Query: 2072 CAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQ 2131
CA GG C++G +G C P S L PP CA H C+ C+D
Sbjct: 661 CASSPCGEGGSCVDG-----ENGFRCLCPPGSLPPLCLPPSHPCA--HEPCSHGI-CYDA 712
Query: 2132 PHGYECSCKTGYTMDNMT-GLCRPVC-AQGCVNGSCVEPD----HCRCHFGFVGRNCS-- 2183
P G+ C C+ G++ + L R C +Q C G D HC C G GR C
Sbjct: 713 PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 772
Query: 2184 ---TECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFC 2239
T C C + C +G C+Q V G C P H C
Sbjct: 773 SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQ----DVDECAGPAPCGP-HGIC 826
Score = 60.5 bits (145), Expect = 2e-08
Identities = 109/477 (22%), Positives = 151/477 (31%), Gaps = 100/477 (20%)
Query: 1986 PPLPCPTPCHLLPNCTSCLDSKGADG--------GWQHCVWSSSLQQCL----------- 2026
P P PC P S G DG G+Q S + +C
Sbjct: 115 PDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTC 174
Query: 2027 --SPSYLPLRCMAGGCGRLLRGP------ESCSLG--CAQA---TQCALCLRRPHCGWCA 2073
+P +C AG G L P C G C Q+ T CL C
Sbjct: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234
Query: 2074 WGGQD-GGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPE----------DECANGHHDC 2122
D G RC+ GG TC G + CPPE DEC + C
Sbjct: 235 VNVDDCPGHRCLNGG--------TCV-DGVNTYNCQCPPEWTGQFCTEDVDECQLQPNAC 285
Query: 2123 NETQNCHDQPHGYECSCKTGYT----MDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFV 2178
+ C + G+ C C G+T N+ VC G V +C C G
Sbjct: 286 HNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-- 343
Query: 2179 GRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGT------C 2232
T C+ C + + N G C P F G A
Sbjct: 344 ----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGA 399
Query: 2233 RPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVN------ 2286
PC R C++ + + + E N GP ++A C++
Sbjct: 400 NPCEHLGR-----CVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFT 454
Query: 2287 --CQNNSYGEKCESCL---QGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTE---- 2337
C G CE + Q ++G K + NG + TC +G CQ + +
Sbjct: 455 CICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC-PSGFSGSTCQLDVDECAS 513
Query: 2338 TGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
T G+ D+ D Y+ +CA E F G+ C R + +C DP C
Sbjct: 514 TPCRNGAKCVDQPDGYECRCA---EGFEGT-----LCDRNV---DDCSPDPCHHGRC 559
Score = 60.1 bits (144), Expect = 3e-08
Identities = 48/164 (29%), Positives = 65/164 (39%), Gaps = 19/164 (11%)
Query: 2083 CMEGGLSGPR-DGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKT 2141
C+ GG+ R +G +C P DECA+ C C DQP GYEC C
Sbjct: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST--PCRNGAKCVDQPDGYECRCAE 535
Query: 2142 GY---TMDNMTGLCRPVCAQGCVNGSCVE---PDHCRCHFGFVGRNCST---ECR---CN 2189
G+ D C P C +G CV+ C C G+ G C + ECR C
Sbjct: 536 GFEGTLCDRNVDDCSP---DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCR 592
Query: 2190 RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCR 2233
+C + + C C + T G +CE + + G CR
Sbjct: 593 HGGKCLDLVDKYLC-RCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Score = 56.6 bits (135), Expect = 3e-07
Identities = 111/462 (24%), Positives = 151/462 (32%), Gaps = 85/462 (18%)
Query: 1007 DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCL-EDCGH-GVC--SG 1062
DVDECR+G C TCLNTP S+ C C GY G + C C + G C SG
Sbjct: 158 DVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG 216
Query: 1063 PPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGC-----SFHSHCRKRGPG-FC---- 1112
+ C C G+ P RC C +++ C G FC
Sbjct: 217 DLTYDCACLPGFEGQ-NCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
Query: 1113 DECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDN-LSGLCF----CQ 1167
DECQ H G+ N G C C G+ + D+ + +CF C
Sbjct: 276 DECQLQPNACH----NGGTCFNTLGGHSC-VCVNGWTGESCSQNIDDCATAVCFHGATCH 330
Query: 1168 DHTEGAHCQLCSPGYYG------DPRAGGSCFREC-------GGRALLTNVSSVALGSRR 1214
D +C C G G D C + GRA+ T
Sbjct: 331 DRVASFYC-ACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICT----------- 378
Query: 1215 VGGLLPPGGGAARAGPGLSYCVWVVSATEELQ-----------PCAPGTLCPPLTLTFSP 1263
PPG + C + E L C G P +
Sbjct: 379 ----CPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNE 434
Query: 1264 DSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEA 1323
S PC + D +F T + + +C D + ++G V
Sbjct: 435 CLSGPCR-NQATCLDRIGQF--TCICMA--GFTGTYCEVDIDECQSSPCVNG-GVCKDRV 488
Query: 1324 NGSSSW---GFNASVGSARCGSGGPGSCPVPQECVPQ-DGAAGAGLCRCPQGWAGPHCRM 1379
NG S GF+ S C +CV Q DG CRC +G+ G C
Sbjct: 489 NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE----CRCAEGFEGTLCDR 544
Query: 1380 AL---CPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLD 1418
+ P+ C H G + C CA G+ G C +++D
Sbjct: 545 NVDDCSPDPC--HHGRCVDGIASFSCACAPGYTGTRCESQVD 584
Score = 55.1 bits (131), Expect = 1e-06
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 10/71 (14%)
Query: 143 PGGCQSHGQCQP-PG---VCACEPGWGGPDC--GLQECS--AYCGSHGTCASPLG--PCR 192
P C+ G+C+ PG VC+C GW GP C + EC+ A CG HG C + G C
Sbjct: 777 PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCT 836
Query: 193 CEPGFLGRACD 203
C G+ G +CD
Sbjct: 837 CHGGYTGPSCD 847
Score = 53.9 bits (128), Expect = 2e-06
Identities = 77/301 (25%), Positives = 96/301 (31%), Gaps = 49/301 (16%)
Query: 1985 SPPLPCPTPCHLLP----------NCTSCLDSKGADGGWQHCVWSSSLQQCLSPS----- 2029
SPP P P P LP CLD G + S CL P
Sbjct: 16 SPPPP-PPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGE 74
Query: 2030 --YLPLRCMAGGCGRLLRGPESCSLGCAQ-ATQCALCLRRPHCGW---CAWGGQDGGGRC 2083
L C +G C S G A+ + +C R P C C G RC
Sbjct: 75 RCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARC 134
Query: 2084 MEGGLSGPRDGLTCGRPGASWAFLSCPPE-DECANGHHDCNETQNCHDQPHGYECSCKTG 2142
G P C P + SC + DEC G C C + P + C C G
Sbjct: 135 SVG----PDGRFLCSCP-PGYQGRSCRSDVDECRVGE-PCRHGGTCLNTPGSFRCQCPAG 188
Query: 2143 YTMDNMTGLCRPVCAQGCVNGSCVEPD-----HCRCHFGFVGRNCST---EC---RCNRH 2191
YT P C NG C C GF G+NC +C RC
Sbjct: 189 YTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNG 248
Query: 2192 SECAGVGARDHCLLCRNHTKGSHC----EQCLPLFVGSAVGGGTCRPCHAFCRGNSHICI 2247
C G + C G C ++C L + GGT C G+S +C+
Sbjct: 249 GTCVD-GVNTYNCQCPPEWTGQFCTEDVDEC-QLQPNACHNGGT---CFNTLGGHSCVCV 303
Query: 2248 S 2248
+
Sbjct: 304 N 304
Score = 53.5 bits (127), Expect = 3e-06
Identities = 99/400 (24%), Positives = 136/400 (34%), Gaps = 83/400 (20%)
Query: 1989 PC-PTPCHLLPNCTSC---LDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLL 2044
PC P PC C S L GWQ + +C P+ C G L
Sbjct: 774 PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPA----PCGPHGICTNL 829
Query: 2045 RGPESCSL-GCAQATQCALCLRRPHCGWCAWGG--QDG-------------GGRC---ME 2085
G SC+ G C + C GG QDG G RC ++
Sbjct: 830 AGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVD 889
Query: 2086 GGLSGPRDGLTCGRPGASWAFLSCPPED---ECANGHHDCNETQ-----NCHDQPHGYEC 2137
LS P TC AS+ +CPP C DC+ + C D + + C
Sbjct: 890 ECLSNPCGPGTCTDHVASFT-CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSC 948
Query: 2138 SCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDH----CRCHFGFVGRNCST------ECR 2187
C+ GYT + P ++ C++G H C C F G C T
Sbjct: 949 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP 1008
Query: 2188 CNRHSECAGVGARDHCLLCRNHTKGSHCE-QCLPLFVGSA-VGGGTCRPCHA----FCRG 2241
C C GA +C LC G C+ + LP +A +G + C A
Sbjct: 1009 CQNGGRCVQTGA--YC-LCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
Query: 2242 NSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQ 2301
+SH C+ E + S +E++ + + P + C+ G CE CL
Sbjct: 1066 SSHYCVC--------PEGRTGSHCEQEVDPCLAQ-PCQHGG---TCRGYMGGYMCE-CLP 1112
Query: 2302 GYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTC 2341
GY C D C Q PCQ+ G+C
Sbjct: 1113 GY-------NGDNCEDDVDECASQ-----PCQHG---GSC 1137
Score = 51.6 bits (122), Expect = 1e-05
Identities = 74/276 (26%), Positives = 90/276 (32%), Gaps = 62/276 (22%)
Query: 968 CLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNT 1027
CL G S GG C+ P W RC D C G C R C ++
Sbjct: 43 CLDG--SPCANGGRCTQLPSREAAC--LCPPGWVGERCQLEDPCHSG--PCAGRGVCQSS 96
Query: 1028 PLS----YECHCQRGYQGDGISHCNRTCLEDCGHGV-CSGPPD--FTCVCDLGWTSDLPP 1080
++ + C C RG++G S + C HG CS PD F C C
Sbjct: 97 VVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSC---------- 146
Query: 1081 PTPAPGPPAPRCSRDCG-CSFHSHCRKRG-----PG-FCDECQDWTWGEHCER------- 1126
PG C D C CR G PG F +C G CE
Sbjct: 147 ---PPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP 203
Query: 1127 --CRPG----SFGNATGSRGCRP------CQ-----CNGHGDPRRGHC-DNLSGL-CFCQ 1167
CR G G+ T C P C+ C GH G C D ++ C C
Sbjct: 204 SPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP 263
Query: 1168 DHTEGAHCQLCSPGYYGDPRA---GGSCFRECGGRA 1200
G C P A GG+CF GG +
Sbjct: 264 PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
Score = 49.7 bits (117), Expect = 4e-05
Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 10/67 (14%)
Query: 148 SHGQCQ--PPGV-CACEPGWGGPDCGLQEC-----SAYCGSHGTCASP-LG-PCRCEPGF 197
SHG C P G C CEPGW GP C S C + GTC+S +G C C PG
Sbjct: 705 SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
Query: 198 LGRACDL 204
GR C+L
Sbjct: 765 QGRQCEL 771
Score = 48.9 bits (115), Expect = 7e-05
Identities = 129/553 (23%), Positives = 170/553 (30%), Gaps = 147/553 (26%)
Query: 1814 SSPEACNQSGACT--------WCHGA-----------------CLSGDQAHRLGCGGSPC 1848
+ P C G CT CHG CL+G G G C
Sbjct: 815 AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQD-GVGSFSC 873
Query: 1849 SPMP--------RSPEECRRLR----TCSECLARHPRTLQPGDG----EASTPRCK--WC 1890
S +P R +EC TC++ +A T PG G E P C C
Sbjct: 874 SCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSC 933
Query: 1891 TN---CPEG----ACIGRNG----SCTSENDCRINQREVFWAGNCSEAACG--------- 1930
N C +G +C+ R G C E D ++ R G CS A G
Sbjct: 934 FNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESF 992
Query: 1931 -AADCEQ---------CTREGKCMWTRQF--------KRTGETRRILSVQPTYDWTCFSH 1972
C+ C G+C+ T + R + R + +
Sbjct: 993 TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLE 1052
Query: 1973 SLLNVSPMPVE--SSPPLPCP---TPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS 2027
L V+ SS CP T H CL GG + +CL
Sbjct: 1053 QLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECL- 1111
Query: 2028 PSY------------LPLRCMAGGCGRLLRGPESCSLGCAQATQCALC-LRRPHCGWCAW 2074
P Y C GG L CS C T LC + CG
Sbjct: 1112 PGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCS--CPPGTLGVLCEINEDDCG--PG 1167
Query: 2075 GGQDGGGRCMEGGLSGPR-DGLTCGRPGASWAFLSCPPE-DECANGHHDCNETQNCHDQP 2132
D G RC+ G G C P + L C + +EC +G T++C P
Sbjct: 1168 PPLDSGPRCLHNGTCVDLVGGFRCTCP-PGYTGLRCEADINECRSGACHAAHTRDCLQDP 1226
Query: 2133 HG-YECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPD---------HCRCHFGFVGRNC 2182
G + C C G++ + P +Q C +G P C C F G C
Sbjct: 1227 GGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRC 1286
Query: 2183 STECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLP--------LFVGSAVG------ 2228
R R +C VG + C+ +G C C P F GS G
Sbjct: 1287 ERVARSCRELQCP-VG-----VPCQQTPRGPRC-ACPPGLSGPSCRSFPGSPPGASNASC 1339
Query: 2229 -------GGTCRP 2234
GG+CRP
Sbjct: 1340 AAAPCLHGGSCRP 1352
Score = 46.2 bits (108), Expect = 4e-04
Identities = 92/412 (22%), Positives = 131/412 (31%), Gaps = 96/412 (23%)
Query: 2048 ESCSLG---CAQAT--QCALCLRRPHCGWCAWGGQDGGGRCM--EGGLSGP--RDGLTCG 2098
ESCS CA A A C R +CA G C + +S P D +
Sbjct: 309 ESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDT 368
Query: 2099 RPGASWAFLSCPPE----------DECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNM 2148
P A +CPP DEC+ G + C C + + C C GYT
Sbjct: 369 NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT---- 424
Query: 2149 TGLCRPVC---AQGCVNGSC---------VEPDHCRCHFGFVGRNCSTECRCNRHSECAG 2196
P C C++G C + C C GF G C + + S C
Sbjct: 425 ----GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN 480
Query: 2197 VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCR----PCHAFCRGNSHICISRKE- 2251
G +C++ G C S G TC+ C + N C+ + +
Sbjct: 481 GG------VCKDRVNGFSCT------CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG 528
Query: 2252 LQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKCT 2311
+ E + +L +++ S D C + C +C GY T
Sbjct: 529 YECRCAEGFEGTLCDRNVDDC-----SPDPCHHGRCVDGIASFSC-ACAPGY-------T 575
Query: 2312 KCQCNGHADTCNEQ------------DGTGCPCQNNTETGTCQ------GSSPSD----R 2349
+C D C Q D C C + T C+ S+P R
Sbjct: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
Query: 2350 RDCYKYQCAKCRESFHGSPLGG---QQCYRLISVEQECCLDPTSQTNCFHEP 2398
+Y C C+ F G PL +C E C+D + C P
Sbjct: 636 DGINRYDCV-CQPGFTG-PLCNVEINECASSPCGEGGSCVDGENGFRCLCPP 685
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 14/72 (19%)
Query: 144 GGCQSHGQCQPPGV-------CACEPGWGGPDCGLQE-CSAYCGSHGTCASPLGP----- 190
G C G CQ V C C G+ GPDC L + C + +HG S +GP
Sbjct: 85 GPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCS-VGPDGRFL 143
Query: 191 CRCEPGFLGRAC 202
C C PG+ GR+C
Sbjct: 144 CSCPPGYQGRSC 155
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 19/87 (21%)
Query: 1344 GPGSCPVPQECVPQDGAAGAGLCR----------CPQGWAGPHCRMALCPENCNAHTGAG 1393
GPG+ P C+ A G C CP GW G C++ P + G G
Sbjct: 35 GPGAAAPP--CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRG 91
Query: 1394 TCNQSLGV------CICAEGFGGPDCA 1414
C S+ C C GF GPDC+
Sbjct: 92 VCQSSVVAGTARFSCRCPRGFRGPDCS 118
Score = 43.1 bits (100), Expect = 0.004
Identities = 36/109 (33%), Positives = 44/109 (40%), Gaps = 22/109 (20%)
Query: 108 PPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQC-QPPG---VCACEPG 163
PPP+ A +LL G A+ L C + G+C Q P C C PG
Sbjct: 21 PPPVRALPLLLLL----------AGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPG 70
Query: 164 WGGPDCGLQE-C-SAYCGSHGTCASPL------GPCRCEPGFLGRACDL 204
W G C L++ C S C G C S + CRC GF G C L
Sbjct: 71 WVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSL 119
Score = 43.1 bits (100), Expect = 0.004
Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 9/72 (12%)
Query: 143 PGGCQSHGQCQPPGV----CACEPGWGGPDCG--LQECSAYCGSHGTCASPLG--PCRCE 194
P C + G CQ GV C+C PG+ GP C + EC + GTC + C C
Sbjct: 855 PNPCLNGGSCQD-GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCP 913
Query: 195 PGFLGRACDLHL 206
PG+ G C+ L
Sbjct: 914 PGYGGFHCEQDL 925
Score = 42.4 bits (98), Expect = 0.006
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 13/103 (12%)
Query: 132 GFNASFRFSLCPGG-CQSHGQCQPPGV----CACEPGWGGPDC--GLQECSAY---CGSH 181
G N CPG C + G C GV C C P W G C + EC C +
Sbjct: 230 GQNCEVNVDDCPGHRCLNGGTCVD-GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNG 288
Query: 182 GTCASPLG--PCRCEPGFLGRACDLHLWENQGAGWWHNVSARD 222
GTC + LG C C G+ G +C ++ + A +H + D
Sbjct: 289 GTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHD 331
Score = 42.4 bits (98), Expect = 0.006
Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 143 PGGCQSHGQCQPPGVCACEPGWGGPDC--GLQECS-AYCGSHGTCASPLGP--CRCEPGF 197
PG C H C C PG+GG C L +CS + C + GTC + C C PG+
Sbjct: 898 PGTCTDH---VASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
Query: 198 LGRAC 202
G C
Sbjct: 955 TGAHC 959
Score = 41.6 bits (96), Expect = 0.011
Identities = 160/699 (22%), Positives = 202/699 (28%), Gaps = 154/699 (22%)
Query: 1753 CNAWLLPDLTRSASVGPPMEESVAHAV---AAVGSRLYISGGFGGVALGRLLAL-TLPPD 1808
C LP L S P E +H + A G R G+ G + LA
Sbjct: 683 CPPGSLPPLCLPPS-HPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ 741
Query: 1809 PCRLLSSPEACNQSGACTWCHGACLSGDQAHRLG-CGGSPCSPMPRSPEECRRLRTCSEC 1867
PCR + + CT G + G Q L C +PC R +L CS C
Sbjct: 742 PCRAGGTCSSDGMGFHCTCPPG--VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS-C 798
Query: 1868 LA--RHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGS--CTSE------------NDC 1911
+ PR Q D A C P G C GS CT NDC
Sbjct: 799 PQGWQGPRCQQDVDECAGPAPCG-----PHGICTNLAGSFSCTCHGGYTGPSCDQDINDC 853
Query: 1912 RINQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFS 1971
N G+C + G+ C C+ R P TC
Sbjct: 854 DPNP--CLNGGSCQDGV-GSFSCS-------CLPGFAGPRCARDVDECLSNPCGPGTCTD 903
Query: 1972 HSLLNVSPMP-------VESSPPLPCPTPCHLLPNCT------SCLDSKGADGGWQHCVW 2018
H P E P P+ C C SCL G G HC
Sbjct: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGA--HC-- 959
Query: 2019 SSSLQQCLSPSYLPLRCMAGG-CGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQ 2077
CLS C+ GG C G L QC + WC+
Sbjct: 960 QHEADPCLSRP-----CLHGGVCSAAHPGFRCTCLESFTGPQCQTLV-----DWCSRQPC 1009
Query: 2078 DGGGRCMEGG---LSGPR--------DGLTCGRPGAS---------WAFLSCPPED---- 2113
GGRC++ G L P L C A A C ED
Sbjct: 1010 QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1069
Query: 2114 ----ECANGHHDCNETQNCHDQP-----------HGYECSCKTGYTMDNMTGLCRPVCAQ 2158
E G H E C QP GY C C GY DN +Q
Sbjct: 1070 CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQ 1129
Query: 2159 GCVN-GSCVE---PDHCRCHFGFVGRNC---STEC----------RCNRHSECAGV--GA 2199
C + GSC++ C C G +G C +C RC + C + G
Sbjct: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1189
Query: 2200 RDHC------LLCR---NHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRK 2250
R C L C N + C GGG CHA G +
Sbjct: 1190 RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPR----CQT 1245
Query: 2251 ELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKC 2310
L + +P ++ + GP +C +G +CE + C
Sbjct: 1246 VLSPCESQPCQHGGQCRP-----SPGPGGGLTFTCHCAQPFWGPRCERVAR-------SC 1293
Query: 2311 TKCQCNGHADTCNEQDGTGCPCQNNTETGTCQ---GSSP 2346
+ QC G C C +C+ GS P
Sbjct: 1294 RELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPP 1332
Score = 40.8 bits (94), Expect = 0.019
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 146 CQSHGQC---QPPGVCACEPGWGGPDC--GLQEC-SAYCGSHGTCASPLGP--CRCEPGF 197
C+ G+C Q +C C G+ GP C + EC S C + TC +G C C GF
Sbjct: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF 461
Query: 198 LGRACDLHLWENQGA 212
G C++ + E Q +
Sbjct: 462 TGTYCEVDIDECQSS 476
Score = 40.0 bits (92), Expect = 0.032
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 17/92 (18%)
Query: 1337 SARCGSGGPG-SCPVPQECVPQDGAAGAG---------LCRCPQGWAGPHCRMALCPENC 1386
S RC G G C +P C+ A GA LC CP G+ G CR + + C
Sbjct: 105 SCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV--DEC 162
Query: 1387 NAH---TGAGTCNQSLGV--CICAEGFGGPDC 1413
GTC + G C C G+ GP C
Sbjct: 163 RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
Score = 39.3 bits (90), Expect = 0.055
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 10/80 (12%)
Query: 132 GFNASFRFSLCPGGCQSHGQCQPPGV----CACEPGWGGPDCGLQ--EC-SAYCGSHGTC 184
G N C + G C+ G+ C C+PG+ GP C ++ EC S+ CG G+C
Sbjct: 614 GVNCEVNIDDCASNPCTFGVCRD-GINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC 672
Query: 185 ASPLG--PCRCEPGFLGRAC 202
C C PG L C
Sbjct: 673 VDGENGFRCLCPPGSLPPLC 692
Score = 38.9 bits (89), Expect = 0.071
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 8/68 (11%)
Query: 146 CQSHGQCQP---PGVCACEPGWGGPDC--GLQECSAY-CGSHGTCASPLGP--CRCEPGF 197
CQ G C+ +C C PG+ G +C + EC++ C G+C + C C PG
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGT 1152
Query: 198 LGRACDLH 205
LG C+++
Sbjct: 1153 LGVLCEIN 1160
Score = 38.1 bits (87), Expect = 0.12
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 8/58 (13%)
Query: 1366 CRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSLG-----VCICAEGFGGPDCATKLD 1418
CRCP+G+ GP C + P+ C + A S+G +C C G+ G C + +D
Sbjct: 106 CRCPRGFRGPDCSL---PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
Score = 37.7 bits (86), Expect = 0.16
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 146 CQSHGQCQP--PGV-CACEPGWGGPDCG--LQECSAY-CGSHGTCASPLGPCRCEPGFLG 199
C G C PG C C + GP C + CS C + G C C C PG+ G
Sbjct: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSG 1030
Query: 200 RACDL 204
R CD+
Sbjct: 1031 RLCDI 1035
Score = 36.6 bits (83), Expect = 0.35
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 16/92 (17%)
Query: 146 CQSHGQC---QPPGVCACEPGWGGPDCGLQE----------CSAYCGSHGTCASPLGP-- 190
CQ G C +C+C PG G C + E C +GTC +G
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR 1190
Query: 191 CRCEPGFLGRACDLHLWENQGAGWWHNVSARD 222
C C PG+ G C+ + E + +G H RD
Sbjct: 1191 CTCPPGYTGLRCEADINECR-SGACHAAHTRD 1221
Score = 35.4 bits (80), Expect = 0.79
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 11/73 (15%)
Query: 143 PGGCQSHGQCQPPGV----CACEPGWGGPDCGLQ--EC-SAYCGSHGTCASPLGP--CRC 193
P C HG+C G+ CAC PG+ G C Q EC S C G C + CRC
Sbjct: 551 PDPCH-HGRCVD-GIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRC 608
Query: 194 EPGFLGRACDLHL 206
G G C++++
Sbjct: 609 PSGTTGVNCEVNI 621
Score = 35.4 bits (80), Expect = 0.79
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 146 CQSHGQCQP---PGVCACEPGWGGPDC--GLQECSAYCGSHGTCASPLG--PCRCEPGFL 198
C+ G+C +C C G G +C + +C++ + G C + C C+PGF
Sbjct: 591 CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFT 650
Query: 199 GRACDLHLWE 208
G C++ + E
Sbjct: 651 GPLCNVEINE 660
Score = 34.7 bits (78), Expect = 1.3
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 146 CQSHGQC-QPPGV--CACEPGWGGPDC---GLQECSAYCGSHGTCASP---LGPCRCEPG 196
C+ G C PG C C G+ GP C + + C + GTC C C PG
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 197 FLGRACDLHL 206
F G+ C++++
Sbjct: 228 FEGQNCEVNV 237
Score = 34.7 bits (78), Expect = 1.3
Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 16/77 (20%)
Query: 142 CPGGCQSHGQCQPPGVCACEPGWGGPDC--------GLQECS---AYCGSHGTC-ASPLG 189
CP G + P CAC PG GP C G S A C G+C +PL
Sbjct: 1298 CPVGVPCQQTPRGPR-CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLA 1356
Query: 190 P---CRCEPGFLGRACD 203
P C C G+ G C+
Sbjct: 1357 PFFRCACAQGWTGPRCE 1373
Score = 33.5 bits (75), Expect = 3.0
Identities = 27/110 (24%), Positives = 32/110 (29%), Gaps = 47/110 (42%)
Query: 141 LCPGGCQSHGQCQPP---GVCACEPGWGGPDC--GLQECSAYCGSHGT----------CA 185
L P C + G C C C GW G C + +C+ HG CA
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCA 339
Query: 186 SPLGP--------------------------------CRCEPGFLGRACD 203
P+G C C PGF G ACD
Sbjct: 340 CPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 389
Score = 33.5 bits (75), Expect = 3.0
Identities = 21/51 (41%), Positives = 23/51 (45%), Gaps = 5/51 (9%)
Query: 158 CACEPGWGGPDCGLQ--EC-SAYCGSHGTCAS-PLG-PCRCEPGFLGRACD 203
C C G+ G C L EC S C + C P G CRC GF G CD
Sbjct: 493 CTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD 543
Score = 33.5 bits (75), Expect = 3.0
Identities = 38/153 (24%), Positives = 48/153 (31%), Gaps = 60/153 (39%)
Query: 146 CQSHGQCQPPGV-CACEPGWGGPDCGL----------------------------QECSA 176
CQ+ G+C G C C PGW G C + ++ S
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
Query: 177 YC-------GSH----------------GTCASPLG--PCRCEPGFLGRACDLHLWENQG 211
YC GSH GTC +G C C PG+ G C+ + E
Sbjct: 1069 YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECAS 1128
Query: 212 AGWWHNVSARDPAFSARIGAAGAFLSPPGLLAV 244
H S D + A PPG L V
Sbjct: 1129 QPCQHGGSCID------LVARYLCSCPPGTLGV 1155
Score = 32.3 bits (72), Expect = 6.7
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 8/73 (10%)
Query: 144 GGCQSHGQCQP---PGVCACEPGWGGPDC--GLQEC-SAYCGSHGTCASPLG--PCRCEP 195
G C++ C C C G+ G C + EC S+ C + G C + C C
Sbjct: 438 GPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
Query: 196 GFLGRACDLHLWE 208
GF G C L + E
Sbjct: 498 GFSGSTCQLDVDE 510
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 92.8 bits (229), Expect = 4e-18
Identities = 124/499 (24%), Positives = 162/499 (32%), Gaps = 138/499 (27%)
Query: 1016 ARCHPRATCLNTPLSYECHCQRGY----------QGDGISHCNRTCLEDCGHGVCSGPPD 1065
+RC + L P++ CHC G+ QG + C++ C C +G
Sbjct: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRC--QCQNGATCDHVT 207
Query: 1066 FTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCE 1125
C C G+T PG P+C + C C C G C W +
Sbjct: 208 GECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCH-HVTGECSCPSGWMGTVCGQ 266
Query: 1126 RCRPGSFGNATGSRGC-RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQ-LCSPGYY 1183
C G FG + C + CQC+ G CD +G C C G CQ C G Y
Sbjct: 267 PCPEGRFG-----KNCSQECQCHNGGT-----CDAATGQCHCSPGYTGERCQDECPVGTY 316
Query: 1184 GDPRA-------GGSCFRECGGRALLTNVSSVALGSRRVGGLLPPG-------------- 1222
G A GG C+ G A L G R L P G
Sbjct: 317 GVLCAETCQCVNGGKCYHVSG--ACLCEAGFA--GERCEARLCPEGLYGIKCDKRCPCHL 372
Query: 1223 ---------GGAARAGPGLS--YCVWVVS------ATEELQPCAPGTLCPPLT--LTFSP 1263
G PG S YC S A +++ C G C +T T +P
Sbjct: 373 ENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAP 432
Query: 1264 -----DSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLV 1318
D STPC L G+ S R CG + D + S
Sbjct: 433 GFKGIDCSTPCPLG------------TYGINCSSR------CGCKNDAVCSPVDGSCTCK 474
Query: 1319 LHWEANG------SSSWGFNASV--------------GSARCGSGGPG------------ 1346
W S +WGF ++ G+ C G G
Sbjct: 475 AGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTY 534
Query: 1347 --SCPVPQECVPQDGA-AGAGLCRCPQGWAGPHCRMALCPEN---------CNAHTGAGT 1394
+C +C DG G CRC GW+G HC ++C E C GA +
Sbjct: 535 GLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCD-SVCAEGRWGPNCSLPCYCKNGA-S 592
Query: 1395 CNQSLGVCICAEGFGGPDC 1413
C+ G+C CA GF G C
Sbjct: 593 CSPDDGICECAPGFRGTTC 611
Score = 92.0 bits (227), Expect = 7e-18
Identities = 157/679 (23%), Positives = 215/679 (31%), Gaps = 135/679 (19%)
Query: 789 GCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPL-CEEHRDCHACTQDP 847
G +Q C C CH G C G T+C C E R C+Q+
Sbjct: 231 GPQCEQRCP-CQNGGVCHHVTGECSCPSGWMG--------TVCGQPCPEGRFGKNCSQE- 280
Query: 848 FCEWHQS---TSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDC-LANSSQCAWCQ 903
C+ H + G CS G + +ECP L E C N +C
Sbjct: 281 -CQCHNGGTCDAATGQCHCSPGYTGE---RCQDECPVGTYGVLCAETCQCVNGGKCYHVS 336
Query: 904 STHTC---FLFAAYLARYPHGGCRGWDDSVHSEPRCRS-CDGFLTCHECLQSHEC----G 955
C F AR G G + + RC + +CH S EC G
Sbjct: 337 GACLCEAGFAGERCEARLCPEGLYG----IKCDKRCPCHLENTHSCHP--MSGECACKPG 390
Query: 956 WCGNEDNPTLGRCLQGDFSGPL----GGGNCSLWVGEGLGLPVALPARWAYARCPDVDEC 1011
W G N T G+ + G +C G+ P + C
Sbjct: 391 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAP-------GFKGIDCSTPC 443
Query: 1012 RLGL--ARCHPRATCLN----TPLSYECHCQRGYQGDGIS----------HCNRTCLEDC 1055
LG C R C N +P+ C C+ G+ G S CN TC C
Sbjct: 444 PLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTC--QC 501
Query: 1056 GHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDEC 1115
+G D TC C GW + G C+ C CS C G C
Sbjct: 502 LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPT-TGHCRCL 560
Query: 1116 QDWTWGEHCER-CRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAH 1174
W+ G HC+ C G +G PC C C G+C C G
Sbjct: 561 PGWS-GVHCDSVCAEGRWGPNCSL----PCYCKNGAS-----CSPDDGICECAPGFRGTT 610
Query: 1175 CQ-LCSPGYYGD--PRAGGSCFRECGGRALLTNVSSVALGSRRVGGL---LPPGGGAARA 1228
CQ +CSPG+YG + C G +T + G G L + P G +
Sbjct: 611 CQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGF--TGALCNEVCPSGRFGKN 668
Query: 1229 GPGLSYCV--WVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDT 1286
G+ C + + C PG + D S PC P
Sbjct: 669 CAGICTCTNNGTCNPIDRSCQCYPGWI--------GSDCSQPCP----------PAHWGP 710
Query: 1287 GVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPG 1346
+ + AFC ++ + G+ + RC G G
Sbjct: 711 NCIHTCNCHNGAFCSA------------------YDGECKCTPGWTGLYCTQRCPLGFYG 752
Query: 1347 S-CPVPQECVPQDGAAG---AGLCRCPQGWAGPHCRMAL--------CPENCNAHTGAGT 1394
C + +C Q+GA +G C C G+ G HC C + C+ + T
Sbjct: 753 KDCALICQC--QNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNS-T 809
Query: 1395 CNQSLGVCICAEGFGGPDC 1413
C+ G C C+ G+ G C
Sbjct: 810 CDHITGTCYCSPGWKGARC 828
Score = 89.4 bits (220), Expect = 5e-17
Identities = 146/606 (24%), Positives = 197/606 (32%), Gaps = 182/606 (30%)
Query: 871 GALKSPEECPPLCSQRLTCEDCLA-NSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS 929
G +S E C P C+ + C+A N+ QC C C G
Sbjct: 97 GFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNC-----------SSACDGDHWG 145
Query: 930 VHSEPRCRSCDGFLTCHECLQSHEC-----GWCGNEDNPTLGRCLQGDFSGPLGGGNCSL 984
H RC+ +G L C+ + C GW + RC QG + G +C
Sbjct: 146 PHCTSRCQCKNGAL-CNPITGACHCAAGFRGWRCED------RCEQGTY-----GNDC-- 191
Query: 985 WVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGI 1044
+ RC +C ATC + ++ EC C GY G
Sbjct: 192 -----------------HQRC-----------QCQNGATCDH--VTGECRCPPGYTGAFC 221
Query: 1045 S----------HCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSR 1094
C + C C +G C C GW + G CS+
Sbjct: 222 EDLCPPGKHGPQCEQRC--PCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQ 279
Query: 1095 DCGCSFHSHCRKRGPGFCDECQDWTWGEHCE-RCRPGSFGNATGSRGCRPCQC-NGHGDP 1152
+C C C G C C GE C+ C G++G CQC NG
Sbjct: 280 ECQCHNGGTC-DAATGQC-HCSPGYTGERCQDECPVGTYGVLCAET----CQCVNG---- 329
Query: 1153 RRGHCDNLSGLCFCQDHTEGAHCQ--LCSPGYYGDPRAGGSCFRECGGRALLTNVSSVAL 1210
G C ++SG C C+ G C+ LC G YG C + C L N S
Sbjct: 330 --GKCYHVSGACLCEAGFAGERCEARLCPEGLYGI-----KCDKRCPCH--LENTHSCH- 379
Query: 1211 GSRRVGGLLPPGGGAARAGPGLS--YCVWVVS------ATEELQPCAPGTLCPPLT--LT 1260
P G PG S YC S A +++ C G C +T T
Sbjct: 380 ----------PMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCT 429
Query: 1261 FSP-----DSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSG 1315
+P D STPC L G+ S R CG + D + S
Sbjct: 430 CAPGFKGIDCSTPCPLGTY------------GINCSSR------CGCKNDAVCSPVDGSC 471
Query: 1316 LLVLHWEANG------SSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCP 1369
W S +WGF ++ + +C +GG C DG C C
Sbjct: 472 TCKAGWHGVDCSIRCPSGTWGFGCNL-TCQCLNGGA--------CNTLDGT-----CTCA 517
Query: 1370 QGWAGPHCRMAL--------CPENCNAHTGAGTCNQSLGVC-------------ICAEGF 1408
GW G C + C E C+ G C+ + G C +CAEG
Sbjct: 518 PGWRGEKCELPCQDGTYGLNCAERCDCSHADG-CHPTTGHCRCLPGWSGVHCDSVCAEGR 576
Query: 1409 GGPDCA 1414
GP+C+
Sbjct: 577 WGPNCS 582
Score = 85.9 bits (211), Expect = 5e-16
Identities = 147/613 (23%), Positives = 205/613 (33%), Gaps = 84/613 (13%)
Query: 790 CLADQGCGWCLTSATCHLRQG--GAHCGDDGAGGSLLVLVPTLCPLCEEHRDCHACTQDP 847
C G + CH G G C D+ G+ VL C C C+ +
Sbjct: 281 CQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQ-CVNGGKCYHVSGAC 339
Query: 848 FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCA------- 900
CE + R C G +K + CP C T C S +CA
Sbjct: 340 LCEAGFAGERCEARLCPE---GLYGIKCDKRCP--CHLENT-HSCHPMSGECACKPGWSG 393
Query: 901 -WCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGN 959
+C T + + + C+ D +C GF +C G G
Sbjct: 394 LYCNETCSPGFYGEACQQIC--SCQNGADCDSVTGKCTCAPGFKGI-DCSTPCPLGTYGI 450
Query: 960 EDNPTLGRCLQGDFSGPLGGGNCSLWVG-EGLGLPVALPA-RWAYARCPDVDECRLGLAR 1017
+ G C P+ G +C+ G G+ + P+ W + C +C G A
Sbjct: 451 NCSSRCG-CKNDAVCSPVDG-SCTCKAGWHGVDCSIRCPSGTWGFG-CNLTCQCLNGGAC 507
Query: 1018 CHPRATCLNTP----LSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLG 1073
TC P E CQ G G +C C DC H P C C G
Sbjct: 508 NTLDGTCTCAPGWRGEKCELPCQDGTYG---LNCAERC--DCSHADGCHPTTGHCRCLPG 562
Query: 1074 WTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCER-CRPGSF 1132
W+ A G P CS C C + C G C EC G C+R C PG +
Sbjct: 563 WSGVHCDSVCAEGRWGPNCSLPCYCKNGASC-SPDDGIC-ECAPGFRGTTCQRICSPGFY 620
Query: 1133 GNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHC-QLCSPGYYGDPRAGGS 1191
G+ S+ C C + G C +++GLC C GA C ++C G +G
Sbjct: 621 GHRC-SQTCPQCVHSS------GPCHHITGLCDCLPGFTGALCNEVCPSGRFG------- 666
Query: 1192 CFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPG 1251
+ C G TN G P + + PG W+ S QPC P
Sbjct: 667 --KNCAGICTCTN-----------NGTCNPIDRSCQCYPG-----WIGSDCS--QPCPPA 706
Query: 1252 TLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLD--TGVVQSDRSLIAAFCGQRRDRPLT 1309
P T + + C+ A+DG + TG+ + R + + +D L
Sbjct: 707 HWGPNCIHTCNCHNGAFCS-----AYDGECKCTPGWTGLYCTQRCPLGFY---GKDCALI 758
Query: 1310 VQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPG-SCPVPQECVPQDGAAG-AGLCR 1367
Q +G H + GF +C SG G C +C+ G C
Sbjct: 759 CQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCY 818
Query: 1368 CPQGWAGPHCRMA 1380
C GW G C A
Sbjct: 819 CSPGWKGARCDQA 831
Score = 85.1 bits (209), Expect = 9e-16
Identities = 171/694 (24%), Positives = 218/694 (31%), Gaps = 127/694 (18%)
Query: 799 CLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDCHA---CTQDPFCEWHQST 855
C A C+ G HC A G C DCH C C+ H +
Sbjct: 154 CKNGALCNPITGACHC----AAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCD-HVT- 207
Query: 856 SRKGDAACSRRGRGRGA--LKSPEECPPLCSQRLTCED---CLANSSQCAWCQSTHTCFL 910
G+ C G L P + P C QR C++ C + +C+ C S +
Sbjct: 208 ---GECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECS-CPSGWMGTV 263
Query: 911 FAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQ 970
G + H+ C + G CH C + C +E L
Sbjct: 264 CGQPCPEGRFGKNCSQECQCHNGGTCDAATG--QCH-CSPGYTGERCQDECPVGTYGVLC 320
Query: 971 GDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGL--ARCHPRATCL--N 1026
+ + GG C G L A +A RC + C GL +C R C N
Sbjct: 321 AETCQCVNGGKCYHVSGACL-----CEAGFAGERC-EARLCPEGLYGIKCDKRCPCHLEN 374
Query: 1027 T----PLSYECHCQRGYQGDGISHCNRTC-----------LEDCGHGVCSGPPDFTCVCD 1071
T P+S EC C+ G+ G +CN TC + C +G C C
Sbjct: 375 THSCHPMSGECACKPGWSG---LYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCA 431
Query: 1072 LGWTSDLPPPTPAP-GPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPG 1130
G+ + TP P G CS CGC + C G C W + RC G
Sbjct: 432 PGFKG-IDCSTPCPLGTYGINCSSRCGCKNDAVCSPVD-GSCTCKAGWHGVDCSIRCPSG 489
Query: 1131 SFGNATGSRGCR-PCQC-NGHGDPRRGHCDNLSGLCFCQDHTEGAHCQL-CSPGYYG--- 1184
++G GC CQC NG G C+ L G C C G C+L C G YG
Sbjct: 490 TWGF-----GCNLTCQCLNG------GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNC 538
Query: 1185 ----DPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPG---------GGAARAGPG 1231
D C G L S V S G P G + G
Sbjct: 539 AERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG 598
Query: 1232 LSYCVWVVSATEELQPCAPG-------TLCPPLTLTFSPDSSTPCTLSYVLA--FDGFPR 1282
+ C T + C+PG CP SS PC L GF
Sbjct: 599 ICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCV-----HSSGPCHHITGLCDCLPGFTG 653
Query: 1283 FLDTGVVQSDR--SLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSS------WGFNAS 1334
L V S R A C + S W + S WG N
Sbjct: 654 ALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNC- 712
Query: 1335 VGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMAL--------CPENC 1386
+ + C +G C DG C+C GW G +C C C
Sbjct: 713 IHTCNCHNGA--------FCSAYDGE-----CKCTPGWTGLYCTQRCPLGFYGKDCALIC 759
Query: 1387 NAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGG 1420
GA C+ G C C GF G C K G
Sbjct: 760 QCQNGAD-CDHISGQCTCRTGFMGRHCEQKCPSG 792
Score = 84.7 bits (208), Expect = 1e-15
Identities = 102/411 (24%), Positives = 135/411 (32%), Gaps = 93/411 (22%)
Query: 1035 CQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSR 1094
C G+ G C C + C HG C P TC C+ GW P C+
Sbjct: 94 CCPGFYESG-EMCVPHCADKCVHGRCIAPN--TCQCEPGWGGTNCSSACDGDHWGPHCTS 150
Query: 1095 DCGCSFHSHCRKRGPGFCDECQDWTWGEHCE-RCRPGSFGNATGSRGCRPCQC-NGHGDP 1152
C C + C G C C G CE RC G++GN R CQC NG
Sbjct: 151 RCQCKNGALCNPI-TGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQR----CQCQNG---- 200
Query: 1153 RRGHCDNLSGLCFCQDHTEGAHCQ-LCSPGYYGDP-------RAGGSCFRECGGRALLTN 1204
CD+++G C C GA C+ LC PG +G + GG C G + +
Sbjct: 201 --ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSG 258
Query: 1205 VSSVALGSRRVGGLLPP---------GGGAARAGPGLSYCVWVVSATEELQPCAPGT--- 1252
G G GG A G +C + C GT
Sbjct: 259 WMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGV 318
Query: 1253 LCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQA 1312
LC + C +G + +G + A F G+R + L +
Sbjct: 319 LCA---------ETCQCV-------NGGKCYHVSGACLCE----AGFAGERCEARLCPEG 358
Query: 1313 LSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGW 1372
L G+ +C P C P G C C GW
Sbjct: 359 LYGI----------------------KCDKRCPCHLENTHSCHPMSGE-----CACKPGW 391
Query: 1373 AGPHCRMA--------LCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCAT 1415
+G +C C + C+ GA C+ G C CA GF G DC+T
Sbjct: 392 SGLYCNETCSPGFYGEACQQICSCQNGA-DCDSVTGKCTCAPGFKGIDCST 441
Score = 63.5 bits (153), Expect = 3e-09
Identities = 156/617 (25%), Positives = 198/617 (32%), Gaps = 146/617 (23%)
Query: 1815 SPEACNQSGACTWCHGACLSGDQAH-RLGCGGSPCSPMPRSPEECRRLRTCSECLARHPR 1873
S E C A HG C++ + G GG+ CS S C
Sbjct: 101 SGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCS---------------SAC------ 139
Query: 1874 TLQPGDGEASTPRCKWCTNCPEGA-CIGRNGSCTSENDCRINQREVFWAGNCSEAACGAA 1932
DG+ P C C GA C G+C C R C + G
Sbjct: 140 -----DGDHWGPHCTSRCQCKNGALCNPITGAC----HCAAGFRGWRCEDRCEQGTYGN- 189
Query: 1933 DCEQ---CTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLP 1989
DC Q C C TGE R P Y F L + P
Sbjct: 190 DCHQRCQCQNGATCDHV-----TGECR----CPPGYTGA-FCEDLCPPGKHGPQCEQRCP 239
Query: 1990 CPTP--CHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSY-----LPLRCMAGGCGR 2042
C CH + SC GW V Q C + +C GG
Sbjct: 240 CQNGGVCHHVTGECSC------PSGWMGTVCG---QPCPEGRFGKNCSQECQCHNGGTCD 290
Query: 2043 LLRGPESCSLG---------CAQATQCALCLRRPHCGWCAWGGQ--DGGGRCM-EGGLSG 2090
G CS G C T LC C GG+ G C+ E G +G
Sbjct: 291 AATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQC---VNGGKCYHVSGACLCEAGFAG 347
Query: 2091 PRD----------GLTCGR--PGASWAFLSCPP-EDECA-----NGHHDCNETQNCHDQP 2132
R G+ C + P SC P ECA +G + CNET C
Sbjct: 348 ERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLY-CNET--CSPGF 404
Query: 2133 HGYEC----SCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRC 2188
+G C SC+ G D++TG C CA G C P C G G NCS+ C C
Sbjct: 405 YGEACQQICSCQNGADCDSVTGKC--TCAPGFKGIDCSTP----CPLGTYGINCSSRCGC 458
Query: 2189 NRHSECAGVGARDHC----------LLCRNHTKGSHCE---QCLPLFVGSAVGGGTCRPC 2235
+ C+ V C + C + T G C QCL GG C
Sbjct: 459 KNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCL--------NGGACNTL 510
Query: 2236 HAFCRGNSHICISRKELQMSKGEPKKYSLD-PEEIENWVTEGPSEDEAVCVNCQNNSYGE 2294
C + EL G Y L+ E + +G C C G
Sbjct: 511 DGTCTCAPGWRGEKCELPCQDG---TYGLNCAERCDCSHADGCHPTTGHC-RCLPGWSGV 566
Query: 2295 KCES-CLQGYFLLDGKCT-KCQCNGHADTCNEQDGTGCPCQNNTETGTCQG-SSPSDRRD 2351
C+S C +G + C+ C C A +C+ DG C C TCQ SP
Sbjct: 567 HCDSVCAEGRW--GPNCSLPCYCKNGA-SCSPDDGI-CECAPGFRGTTCQRICSPG---- 618
Query: 2352 CYKYQCAK-CRESFHGS 2367
Y ++C++ C + H S
Sbjct: 619 FYGHRCSQTCPQCVHSS 635
Score = 58.9 bits (141), Expect = 7e-08
Identities = 66/265 (24%), Positives = 98/265 (36%), Gaps = 71/265 (26%)
Query: 2151 LCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCS-------------TECRCNRHSECAGV 2197
+C P CA CV+G C+ P+ C+C G+ G NCS + C+C + C +
Sbjct: 104 MCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPI 163
Query: 2198 GARDHCLL----------CRNHTKGSHCEQCLPLFVGS----AVGGGTCRPCH--AFCRG 2241
HC C T G+ C Q G+ G C P + AFC
Sbjct: 164 TGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFC-- 221
Query: 2242 NSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVC------VNCQNNSYGEK 2295
+C P K+ E+ P ++ VC +C + G
Sbjct: 222 -EDLC-----------PPGKHGPQCEQ------RCPCQNGGVCHHVTGECSCPSGWMGTV 263
Query: 2296 C-ESCLQGYFLLDGK-CT-KCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDC 2352
C + C +G F GK C+ +CQC+ + TC+ G C C CQ P
Sbjct: 264 CGQPCPEGRF---GKNCSQECQCH-NGGTCDAATGQ-CHCSPGYTGERCQDECPV---GT 315
Query: 2353 YKYQCAKCRESFHGSPLGGQQCYRL 2377
Y CA+ + +G +CY +
Sbjct: 316 YGVLCAETCQCVNGG-----KCYHV 335
Score = 58.9 bits (141), Expect = 7e-08
Identities = 104/457 (22%), Positives = 146/457 (31%), Gaps = 112/457 (24%)
Query: 1818 ACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLRTCSECLARHPRTLQP 1877
+C C G C + C +PC P + S C ++ P
Sbjct: 414 SCQNGADCDSVTGKCTCAPGFKGIDCS-TPC------PLGTYGINCSSRCGCKNDAVCSP 466
Query: 1878 GDGEASTPRCKW----CT-NCPEG----------------ACIGRNGSCTSE-----NDC 1911
DG T + W C+ CP G AC +G+CT C
Sbjct: 467 VDGSC-TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKC 525
Query: 1912 RINQREVFWAGNCSEAA-CGAAD-CEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTC 1969
+ ++ + NC+E C AD C T +C+ W
Sbjct: 526 ELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCL--------------------PGW-- 563
Query: 1970 FSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCV---WSSSLQQCL 2026
S ++ + E C PC+ N SC D G C ++ Q+
Sbjct: 564 ---SGVHCDSVCAEGRWGPNCSLPCYC-KNGASC----SPDDGICECAPGFRGTTCQRIC 615
Query: 2027 SPSYLPLRCMAGGCGRLLRGPESCS-----LGCAQATQCALCLRRPHCGWCAWGGQDGG- 2080
SP + RC + C + + C C ALC C +G G
Sbjct: 616 SPGFYGHRC-SQTCPQCVHSSGPCHHITGLCDCLPGFTGALC--NEVCPSGRFGKNCAGI 672
Query: 2081 GRCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHD----QPHGYE 2136
C G P D PG W C A+ +C T NCH+ + E
Sbjct: 673 CTCTNNGTCNPIDRSCQCYPG--WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE 730
Query: 2137 CSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAG 2196
C C G+T GL C Q RC GF G++C+ C+C ++C
Sbjct: 731 CKCTPGWT-----GL---YCTQ-------------RCPLGFYGKDCALICQCQNGADCDH 769
Query: 2197 VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCR 2233
+ + CR G HCEQ P S G CR
Sbjct: 770 ISGQ---CTCRTGFMGRHCEQKCP----SGTYGYGCR 799
Score = 56.6 bits (135), Expect = 3e-07
Identities = 32/93 (34%), Positives = 39/93 (41%), Gaps = 22/93 (23%)
Query: 132 GFNASFRFSLCPGG-----------CQSHGQCQP-PGVCACEPGWGGPDCGL-------- 171
G+ +F LCP G CQ+ G C G C+C GW G CG
Sbjct: 215 GYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG 274
Query: 172 QECSAYCGSH--GTCASPLGPCRCEPGFLGRAC 202
+ CS C H GTC + G C C PG+ G C
Sbjct: 275 KNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
Score = 52.4 bits (124), Expect = 6e-06
Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 10/65 (15%)
Query: 149 HGQCQPPGVCACEPGWGGPDCGL--------QECSAYCG-SHGTCASPL-GPCRCEPGFL 198
HG+C P C CEPGWGG +C C++ C +G +P+ G C C GF
Sbjct: 115 HGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFR 174
Query: 199 GRACD 203
G C+
Sbjct: 175 GWRCE 179
Score = 51.2 bits (121), Expect = 1e-05
Identities = 67/285 (23%), Positives = 85/285 (29%), Gaps = 69/285 (24%)
Query: 1178 CSPGYYGDPRAGGSCFRECG-----GRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGL 1232
C PG+Y +G C C GR + N PG G
Sbjct: 94 CCPGFY---ESGEMCVPHCADKCVHGRCIAPNTCQCE-----------PGWGGTNCSSAC 139
Query: 1233 SYCVWVVSATEELQPCAPGTLCPPLTL--------------------TFSPDSSTPCTLS 1272
W T Q C G LC P+T T+ D C
Sbjct: 140 DGDHWGPHCTSRCQ-CKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ 198
Query: 1273 YVLAFDGFPRFLDTGVVQSDRSLIAAFC---------GQRRDRPLTVQALSGLLVLHWEA 1323
D TG + AFC G + ++ Q +G + H
Sbjct: 199 NGATCDHV-----TGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQ--NGGVCHHVTG 251
Query: 1324 NGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA---AGAGLCRCPQGWAGPHCRM- 1379
S G+ +V C G G QEC +G A G C C G+ G C+
Sbjct: 252 ECSCPSGWMGTVCGQPCPEGRFGK-NCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDE 310
Query: 1380 -------ALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKL 1417
LC E C G G C G C+C GF G C +L
Sbjct: 311 CPVGTYGVLCAETCQCVNG-GKCYHVSGACLCEAGFAGERCEARL 354
Score = 50.4 bits (119), Expect = 2e-05
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 16/84 (19%)
Query: 132 GFNASFRFSLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQ----------ECSAYCGS 180
G N S R GC++ C P G C C+ GW G DC ++ + C +
Sbjct: 449 GINCSSRC-----GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLN 503
Query: 181 HGTCASPLGPCRCEPGFLGRACDL 204
G C + G C C PG+ G C+L
Sbjct: 504 GGACNTLDGTCTCAPGWRGEKCEL 527
Score = 47.8 bits (112), Expect = 2e-04
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 22/95 (23%)
Query: 130 LLGFNASFRFSLCPGG-----------CQSHGQCQP-PGVCACEPGWGGPDCGLQ----- 172
L GF + +CP G C ++G C P C C PGW G DC
Sbjct: 648 LPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAH 707
Query: 173 ---ECSAYCGSHGT--CASPLGPCRCEPGFLGRAC 202
C C H C++ G C+C PG+ G C
Sbjct: 708 WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYC 742
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 13/73 (17%)
Query: 142 CPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQECS-----------AYCGSHGTCASPLG 189
CP ++ C P G CAC+PGW G C + CS C + C S G
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLYCN-ETCSPGFYGEACQQICSCQNGADCDSVTG 426
Query: 190 PCRCEPGFLGRAC 202
C C PGF G C
Sbjct: 427 KCTCAPGFKGIDC 439
Score = 45.1 bits (105), Expect = 0.001
Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 25/94 (26%)
Query: 132 GFNASFRFSLCPGG-----------CQSHGQCQP-PGVCACEPGWGGPDCGLQ------- 172
G + S R CP G C + G C G C C PGW G C L
Sbjct: 479 GVDCSIR---CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYG 535
Query: 173 -ECSAYCG-SHGT-CASPLGPCRCEPGFLGRACD 203
C+ C SH C G CRC PG+ G CD
Sbjct: 536 LNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCD 569
Score = 45.1 bits (105), Expect = 0.001
Identities = 24/68 (35%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDCGL--------QECS--AYCGSHGTCASPLGPCRCE 194
C C P G C C PGW G C CS YC + +C+ G C C
Sbjct: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
Query: 195 PGFLGRAC 202
PGF G C
Sbjct: 604 PGFRGTTC 611
Score = 44.3 bits (103), Expect = 0.002
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 9/63 (14%)
Query: 1366 CRCPQGWAGPHCRMAL--------CPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKL 1417
C+C GW G +C A C C GA CN G C CA GF G C +
Sbjct: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGA-LCNPITGACHCAAGFRGWRCEDRC 182
Query: 1418 DGG 1420
+ G
Sbjct: 183 EQG 185
Score = 44.3 bits (103), Expect = 0.002
Identities = 33/104 (31%), Positives = 40/104 (38%), Gaps = 15/104 (14%)
Query: 1330 GFNASVGSARCGSGGPGSCPVPQECVPQDGAAG---AGLCRCPQGWAGPHCRMALCP--- 1383
GF RC G G+ Q C Q+GA G CRCP G+ G C LCP
Sbjct: 172 GFRGWRCEDRCEQGTYGN-DCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE-DLCPPGK 229
Query: 1384 ------ENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQ 1421
+ C G G C+ G C C G+ G C G+
Sbjct: 230 HGPQCEQRCPCQNG-GVCHHVTGECSCPSGWMGTVCGQPCPEGR 272
Score = 43.9 bits (102), Expect = 0.002
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 15/79 (18%)
Query: 142 CPGGCQSH--GQCQPP-GVCACEPGWGGPDCGLQEC-----------SAYCGSHGTCASP 187
C CQ H G C G C C PG+ G C EC + C + G C
Sbjct: 277 CSQECQCHNGGTCDAATGQCHCSPGYTGERCQ-DECPVGTYGVLCAETCQCVNGGKCYHV 335
Query: 188 LGPCRCEPGFLGRACDLHL 206
G C CE GF G C+ L
Sbjct: 336 SGACLCEAGFAGERCEARL 354
Score = 43.1 bits (100), Expect = 0.004
Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 13/74 (17%)
Query: 143 PGGCQSHGQCQPP-GVCACEPGWGGPDCGL------------QECSAYCGSHGTCASPLG 189
P C++ C P G+C C PG+ G C Q C S G C G
Sbjct: 584 PCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITG 643
Query: 190 PCRCEPGFLGRACD 203
C C PGF G C+
Sbjct: 644 LCDCLPGFTGALCN 657
Score = 39.3 bits (90), Expect = 0.055
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 11/72 (15%)
Query: 142 CPGGCQSHGQCQP-PGVCACEPGWGGPDCGL--------QECSAYCG--SHGTCASPLGP 190
CP S G C G+C C PG+ G C + C+ C ++GTC
Sbjct: 628 CPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS 687
Query: 191 CRCEPGFLGRAC 202
C+C PG++G C
Sbjct: 688 CQCYPGWIGSDC 699
Score = 38.1 bits (87), Expect = 0.12
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 16/79 (20%)
Query: 141 LCPGGCQ--SHGQC-QPPGVCACEPGWGGPDCGLQ---------ECSAYCGSH----GTC 184
LC CQ + G+C G C CE G+ G C + +C C H +C
Sbjct: 319 LCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSC 378
Query: 185 ASPLGPCRCEPGFLGRACD 203
G C C+PG+ G C+
Sbjct: 379 HPMSGECACKPGWSGLYCN 397
Score = 38.1 bits (87), Expect = 0.12
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 15/85 (17%)
Query: 131 LGFNASFRFSLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQECSAY-----------C 178
LGF +C CQ+ C G C C G+ G C Q+C + C
Sbjct: 748 LGFYGKDCALICQ--CQNGADCDHISGQCTCRTGFMGRHCE-QKCPSGTYGYGCRQICDC 804
Query: 179 GSHGTCASPLGPCRCEPGFLGRACD 203
++ TC G C C PG+ G CD
Sbjct: 805 LNNSTCDHITGTCYCSPGWKGARCD 829
Score = 36.2 bits (82), Expect = 0.46
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 11/68 (16%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDC---------GLQ-ECSAYCGSHGTCASPLGPCRCE 194
CQ+ C G C C PG+ G C G Q E C + G C G C C
Sbjct: 197 CQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCP 256
Query: 195 PGFLGRAC 202
G++G C
Sbjct: 257 SGWMGTVC 264
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 92.8 bits (229), Expect = 4e-18
Identities = 165/682 (24%), Positives = 208/682 (30%), Gaps = 143/682 (20%)
Query: 799 CLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDCHACTQDPFC-EWHQSTSR 857
C CH G C D G G L C C+++ C + H +
Sbjct: 613 CANRGRCHRLYGACLC-DPGLYGRFCHLT------CPPWAFGPGCSEECQCVQPHTQSCD 665
Query: 858 KGDAACSRRGRGRGALKSPEECP-----PLCSQRLTCEDCLANSSQCAWCQSTHTCFLFA 912
K D +CS + RG + EC P C Q TC +A S C
Sbjct: 666 KRDGSCSCKAGFRGE-RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGK-------- 716
Query: 913 AYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGD 972
R P G E + C C S CG G + G+C
Sbjct: 717 ----RCPAG--------FQGEDCGQECPVGTFGVNCSSSCSCG--GAPCHGVTGQC---- 758
Query: 973 FSGPLG--GGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRA-TCLNTP- 1028
P G G +C EG RW C ++ ARC P CL P
Sbjct: 759 -RCPPGRTGEDCEADCPEG---------RWGLG-CQEICPACQHAARCDPETGACLCLPG 807
Query: 1029 -LSYECH--CQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAP 1085
+ C C G+ G C C C + P C C GWT
Sbjct: 808 FVGSRCQDVCPAGWYGPS---CQTRC--SCANDGHCHPATGHCSCAPGWTGFSCQRACDT 862
Query: 1086 GPPAPRCSRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCER-CRPGSFGNATGS 1138
G P CS C CS G G CD C+ G CE+ C G FG
Sbjct: 863 GHWGPDCSHPCNCS-------AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQ 915
Query: 1139 RGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQ-LCSPGYYG-DPRAGGSCFREC 1196
R CQC HG CD++SG C C G C+ C G++G D R+ +C
Sbjct: 916 R----CQCQ-HG----AACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNC--TA 964
Query: 1197 GGRALLTNVSSVALGSRR------------------------VGGLLPPGGGAARAGPGL 1232
G N S + RR G P G PG
Sbjct: 965 GAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGW 1024
Query: 1233 --SYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYV-LAFDG--FPRFLDTG 1287
C+ A C LC C + LA + PR + G
Sbjct: 1025 MGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAG 1084
Query: 1288 VVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGS 1347
S L C R L +G + G+ + RC S
Sbjct: 1085 CRHSGGCLNGGLCDPHTGRCLCPAGWTG-----DKCQSPCLRGWFGEACAQRC------S 1133
Query: 1348 CPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMAL--------CPENCNAHTGAGTCNQSL 1399
CP C GA CRCP G+ G C A C + C C+ +
Sbjct: 1134 CPPGAACHHVTGA-----CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPAT 1188
Query: 1400 GVCICAEGFGGPDCATKLDGGQ 1421
G C CA G+ GP C + G+
Sbjct: 1189 GTCSCAAGYHGPSCQQRCPPGR 1210
Score = 89.0 bits (219), Expect = 6e-17
Identities = 139/540 (25%), Positives = 172/540 (31%), Gaps = 154/540 (28%)
Query: 775 PYRSSSCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLC 834
P + +C +++ C Q C C A+C G HC G S L CP
Sbjct: 984 PRCAETCPAHTYGHNC--SQACA-CFNGASCDPVHGQCHCAPGWMGPSCL----QACPAG 1036
Query: 835 EEHRDC-HAC------TQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRL 887
+C H+C T DP G AC G L +EC P R
Sbjct: 1037 LYGDNCRHSCLCQNGGTCDPV---------SGHCACPE---GWAGLACEKECLPR-DVRA 1083
Query: 888 TCED---CLANSSQCAWCQSTHTCFLFAAYLARYPHGGC-RGWDDSVHSEPRCRSCDGFL 943
C CL N C T C A + C RGW ++ RC SC
Sbjct: 1084 GCRHSGGCL-NGGLCD--PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQ-RC-SCPPGA 1138
Query: 944 TCH----------------------------ECLQSHECGWCGNEDNPTLGRC-LQGDFS 974
CH +C Q +C +P G C +
Sbjct: 1139 ACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH 1198
Query: 975 GP---------------------LGGGNCSLWVGE--------GLGLPVALPARWAYARC 1005
GP L GG+C G G + P C
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 1006 PDVDECRLGLARCHP-RATCLNTPLSYECHCQRGYQGDGIS-HCNRTCLEDCGHGVCSGP 1063
V C G A C P TCL P C+RG + C TC C +G
Sbjct: 1259 THVCGCGQGAA-CDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTC--SCRNGGLCHA 1315
Query: 1064 PDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCR------KRGPGF----CD 1113
+ +C C LGWT PG C +C C +S C + GPGF C+
Sbjct: 1316 SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Query: 1114 E----------CQDWTWGEH---------------------CER-CRPGSFGNATGSRGC 1141
CQ W +H CER C PGSFG R
Sbjct: 1376 HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQR-- 1433
Query: 1142 RPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQL-CSPGYYGDPRAGGSCFRECGGRA 1200
C C+G G P CD ++GLC C GA C L C G +G P C +CGG A
Sbjct: 1434 --CDCDG-GAP----CDPVTGLCLCPPGRSGATCNLDCRRGQFG-PSCTLHC--DCGGGA 1483
Score = 87.0 bits (214), Expect = 2e-16
Identities = 173/697 (24%), Positives = 218/697 (31%), Gaps = 168/697 (24%)
Query: 778 SSSCTSYSSCLGCLADQGC--GW----CLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLC 831
S +CT + G + C G+ C ++ C GA C D GS L
Sbjct: 929 SGACTCPAGWRGTFCEHACPAGFFGLDCRSACNC---TAGAAC--DAVNGSCLCPAGRRG 983
Query: 832 PLCEE----HRDCHACTQDPFCEWHQSTSR-KGDAACSRRGRGRGALKSPEECPPLCSQR 886
P C E H H C+Q C S G C+ G L++ C
Sbjct: 984 PRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQA-------CPAG 1036
Query: 887 LTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGC-RGWDDSVHSEPRCRSCDGFLTC 945
L ++C CQ+ TC + + A C GW + E C D C
Sbjct: 1037 LYGDNC----RHSCLCQNGGTCDPVSGHCA------CPEGWA-GLACEKECLPRDVRAGC 1085
Query: 946 HE---CLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAY 1002
CL C +P GRCL P G W G+ P W
Sbjct: 1086 RHSGGCLNGGLC-------DPHTGRCLC-----PAG------WTGDKCQSPCL--RGWFG 1125
Query: 1003 ARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCL-----EDC-- 1055
C C G A CH ++ C C G+ G G C + C EDC
Sbjct: 1126 EACAQRCSCPPGAA-CHH--------VTGACRCPPGFTGSG---CEQACPPGSFGEDCAQ 1173
Query: 1056 -----GHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPG 1110
G P TC C G+ PG P C + CGC C G
Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSC-DAATG 1232
Query: 1111 FCDECQDWTWGEHCE-RCRPGSFG-NATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQD 1168
C C G C C G FG N T GC G G CD ++G C C
Sbjct: 1233 AC-RCPTGFLGTDCNLTCPQGRFGPNCTHVCGC------GQG----AACDPVTGTCLCPP 1281
Query: 1169 HTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARA 1228
G C+ P R G C C S R GGL G+
Sbjct: 1282 GRAGVRCERGCP----QNRFGVGCEHTC---------------SCRNGGLCHASNGSCSC 1322
Query: 1229 GPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGV 1288
G G W E C PG L S +++ C + TG
Sbjct: 1323 GLG-----WTGRHCE--LACPPGRYGAACHLECSCHNNSTCEPA-------------TGT 1362
Query: 1289 VQSDRSLIAAFCGQRRDRPLTVQAL-SGLLVLHWEANGS----------SSWGFNASVGS 1337
+ F GQ + P +G L W +G+ GF+
Sbjct: 1363 CRCG----PGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCE 1418
Query: 1338 ARCGSGGPG-SCPVPQECVPQDGAAG----AGLCRCPQGWAGP----HCRMALCPENCNA 1388
C G G C +C DG A GLC CP G +G CR +C
Sbjct: 1419 RGCEPGSFGEGCHQRCDC---DGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTL 1475
Query: 1389 HT---GAGTCNQSLGVCICAEGFGGPDCATKLDGGQL 1422
H G C+ G C C +G+ GP C +GG L
Sbjct: 1476 HCDCGGGADCDPVSGQCHCVDGYMGPTCR---EGGPL 1509
Score = 75.1 bits (183), Expect = 9e-13
Identities = 103/434 (23%), Positives = 135/434 (31%), Gaps = 92/434 (21%)
Query: 796 CGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDCH---ACTQDPFCEWH 852
C C TC L G C + G ++ CP ++C +C C+
Sbjct: 524 CDDCRNGGTCLLGLDGCDCPEGWTG----LICNETCPPDTFGKNCSFSCSCQNGGTCD-- 577
Query: 853 QSTSRKGDAACSRRGRGRGALKSPEECPP-----LCSQRLTCEDCLANSSQCAWCQSTHT 907
S G C G + CP C ++ C AN +C
Sbjct: 578 ---SVTGACRCPP---GVSGTNCEDGCPKGYYGKHCRKKCNC----ANRGRCHRLYGA-- 625
Query: 908 CFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGR 967
C R+ H C W C +C+Q H C D G
Sbjct: 626 CLCDPGLYGRFCHLTCPPWAFGPGCSEEC----------QCVQPHTQS-CDKRD----GS 670
Query: 968 C-LQGDFSGPLGGGNCSL-WVGEGLGLPVALPARWAY--------ARCPDV-------DE 1010
C + F G C L + G G P A RCP E
Sbjct: 671 CSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE 730
Query: 1011 CRLGL--ARCHPRATCLNTP---LSYECHCQRGYQGDGISHCNRTCLED----------- 1054
C +G C +C P ++ +C C G G+ C C E
Sbjct: 731 CPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGED---CEADCPEGRWGLGCQEICP 787
Query: 1055 -CGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCD 1113
C H P C+C G+ G P C C C+ HC G C
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHP-ATGHCS 846
Query: 1114 ECQDWTWGEHCER-CRPGSFGNATGSRGCRPCQCN-GHGDPRRGHCDNLSGLCFCQDHTE 1171
WT G C+R C G +G PC C+ GHG CD +SGLC C+
Sbjct: 847 CAPGWT-GFSCQRACDTGHWGPDCS----HPCNCSAGHGS-----CDAISGLCLCEAGYV 896
Query: 1172 GAHC-QLCSPGYYG 1184
G C Q C G++G
Sbjct: 897 GPRCEQQCPQGHFG 910
Score = 75.1 bits (183), Expect = 9e-13
Identities = 152/635 (23%), Positives = 195/635 (30%), Gaps = 141/635 (22%)
Query: 1819 CNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSP---EECRRLRTCSECLARHPRTL 1875
C G C +GACL + C + C P P EEC +C+ H ++
Sbjct: 613 CANRGRCHRLYGACLCDPGLYGRFCHLT-CPPWAFGPGCSEEC-------QCVQPHTQSC 664
Query: 1876 QPGDGEAST-------------------PRCKWCTNCPEG-ACIGRNGSCTSE------- 1908
DG S P C CP G AC +G C
Sbjct: 665 DKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQG 724
Query: 1909 NDCRINQREVFWAGNCSEA-ACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDW 1967
DC + NCS + +CG A C T + +C RTGE + +
Sbjct: 725 EDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRC----PPGRTGEDCEADCPEGRWGL 780
Query: 1968 TCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQ------------- 2014
C + P ++ P C LP GW
Sbjct: 781 GC-----QEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND 835
Query: 2015 -HCVWSSSLQQCLSPSYLPLRCM----AGGCGRLLRGPESCSLG---CAQATQCALC--- 2063
HC ++ C +P + C G G P +CS G C + LC
Sbjct: 836 GHCHPATGHCSC-APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAG 894
Query: 2064 LRRPHCGWCAWGGQDGGG-----RCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANG 2118
P C G G G +C G G C P A W C E C G
Sbjct: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG-ACTCP-AGWRGTFC--EHACPAG 950
Query: 2119 HH--DCNETQNCH-----DQPHGYECSCKTGYTMDNMTGLCRP-----VCAQGCV--NGS 2164
DC NC D +G C C G C C+Q C NG+
Sbjct: 951 FFGLDCRSACNCTAGAACDAVNG-SCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGA 1009
Query: 2165 CVEPDHCRCH---------------FGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNH 2209
+P H +CH G G NC C C C V HC C
Sbjct: 1010 SCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSG--HC-ACPEG 1066
Query: 2210 TKGSHCE-QCLPLFV-------GSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGE--- 2258
G CE +CLP V G + GG C P C + + + +G
Sbjct: 1067 WAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGE 1126
Query: 2259 --PKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCE-SCLQGYFLLDGKCTK-CQ 2314
++ S P + VT C C G CE +C G F D C + CQ
Sbjct: 1127 ACAQRCSCPPGAACHHVT-------GAC-RCPPGFTGSGCEQACPPGSFGED--CAQMCQ 1176
Query: 2315 CNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDR 2349
C G C+ GT C C +CQ P R
Sbjct: 1177 CPGENPACHPATGT-CSCAAGYHGPSCQQRCPPGR 1210
Score = 61.2 bits (147), Expect = 1e-08
Identities = 104/408 (25%), Positives = 126/408 (30%), Gaps = 87/408 (21%)
Query: 1042 DGISH-CNRTCLEDCGHG-VCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCS 1099
D H C+ TC +DC +G C D C C GWT + T P CS C C
Sbjct: 514 DSFGHDCSLTC-DDCRNGGTCLLGLD-GCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQ 571
Query: 1100 FHSHCRKRGPGFCDECQDWTWGEHCER-CRPGSFGNATGSRGCRP-CQCNGHGDPRRGHC 1157
C G C C G +CE C G +G + CR C C RG C
Sbjct: 572 NGGTCDSV-TGAC-RCPPGVSGTNCEDGCPKGYYG-----KHCRKKCNC-----ANRGRC 619
Query: 1158 DNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSC------FRECGGRALLTNVSSVALG 1211
L G C C G C L P + P C + C R + + G
Sbjct: 620 HRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRG 679
Query: 1212 SRRVG----GLLPPGGGAARAGPGLSYCVWVVSATEELQPCA-----PGTLCPPLTLTFS 1262
R G PG A P C V + P G CP T +
Sbjct: 680 ERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVN 739
Query: 1263 PDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWE 1322
SS C G P TG + C D P
Sbjct: 740 CSSSCSC--------GGAPCHGVTGQCRCPPGRTGEDC--EADCP--------------- 774
Query: 1323 ANGSSSWGFN------ASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRC----PQGW 1372
WG A +ARC P C+ G G+ RC P GW
Sbjct: 775 ---EGRWGLGCQEICPACQHAARCD-------PETGACLCLPGFVGS---RCQDVCPAGW 821
Query: 1373 AGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGG 1420
GP C+ C+ G C+ + G C CA G+ G C D G
Sbjct: 822 YGPSCQ-----TRCSC-ANDGHCHPATGHCSCAPGWTGFSCQRACDTG 863
Score = 59.7 bits (143), Expect = 4e-08
Identities = 148/615 (24%), Positives = 182/615 (29%), Gaps = 121/615 (19%)
Query: 1828 CHGACLSG----DQAHRLGCGGSPCSPMPRSPEECRRLRTCSECLARH--PRTLQPGDGE 1881
C AC +G D +H C S C + C A + PR Q
Sbjct: 856 CQRACDTGHWGPDCSHPCNCSAGHGS--------CDAISGLCLCEAGYVGPRCEQQCPQG 907
Query: 1882 ASTPRCKWCTNCPEGA-CIGRNGSCTSENDCRINQREVFWAGNCSEAACGAA----DCEQ 1936
P C+ C GA C +G+CT W G E AC A DC
Sbjct: 908 HFGPGCEQRCQCQHGAACDHVSGACTCPAG---------WRGTFCEHACPAGFFGLDCRS 958
Query: 1937 ---CTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPT- 1992
CT C RR P TC +H+ + C
Sbjct: 959 ACNCTAGAACDAVNGSCLCPAGRR----GPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
Query: 1993 --PCHLLPNCT--SCLDSKGADGGWQHCVWSSSLQQ--CLSPSYLPLRCMAGGCGRLLRG 2046
CH P SCL + A +C S Q P C G G
Sbjct: 1015 HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEK 1074
Query: 2047 ---PESCSLGCAQATQC---ALCLRRPHCGWC----AWGGQDGGGRCMEGGLSGPRDGLT 2096
P GC + C LC PH G C W G C+ G
Sbjct: 1075 ECLPRDVRAGCRHSGGCLNGGLC--DPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRC 1132
Query: 2097 CGRPGASWAFLS----CPP-------EDECANGH--HDCNETQNCHDQ-----PHGYECS 2138
PGA+ ++ CPP E C G DC + C + P CS
Sbjct: 1133 SCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCS 1192
Query: 2139 CKTGYTMDNMTGLCRPV-----CAQ--GCVNG-SC-VEPDHCRCHFGFVGRNCSTECRCN 2189
C GY + C P C Q GC+NG SC CRC GF+G +C+ C
Sbjct: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQG 1252
Query: 2190 RH----SECAGVGARDHC------LLCRNHTKGSHCEQCLP---LFVG-----SAVGGGT 2231
R + G G C LC G CE+ P VG S GG
Sbjct: 1253 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1312
Query: 2232 CRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNS 2291
C + C EL P +Y + E C
Sbjct: 1313 CHASNGSCSCGLGWTGRHCELAC---PPGRYGAACHLECSCHNNSTCEPATGTCRCGPGF 1369
Query: 2292 YGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTG-CP-------CQNNTETGT--- 2340
YG+ CE F G C C H C+ G CP C+ E G+
Sbjct: 1370 YGQACEHPCPPGFHGAGCQGLCWCQ-HGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGE 1428
Query: 2341 -------CQGSSPSD 2348
C G +P D
Sbjct: 1429 GCHQRCDCDGGAPCD 1443
Score = 55.8 bits (133), Expect = 6e-07
Identities = 91/391 (23%), Positives = 136/391 (34%), Gaps = 102/391 (26%)
Query: 2034 RCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRD 2093
RC G G +C GC + C ++ +C + G + GL G
Sbjct: 584 RCPPGVSGT------NCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFC 637
Query: 2094 GLTCGRPGASWAF-LSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLC 2152
LTC WAF C E +C H TQ+C D+ G CSCK G+ + C
Sbjct: 638 HLTC----PPWAFGPGCSEECQCVQPH-----TQSC-DKRDG-SCSCKAGFRGERCQAEC 686
Query: 2153 R-----PVCAQGC----------VNGSC-------VEPDHC--RCHFGFVGRNCSTECRC 2188
P C Q C V+G C + + C C G G NCS+ C C
Sbjct: 687 ELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC 746
Query: 2189 ---------------------NRHSECA----GVGARDHCLLCRNHTKGSHCEQ------ 2217
+ ++C G+G ++ C C++ + C+
Sbjct: 747 GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQH---AARCDPETGACL 803
Query: 2218 CLPLFVGSAVG--------GGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEI 2269
CLP FVGS G +C+ C + H + + G +
Sbjct: 804 CLPGFVGSRCQDVCPAGWYGPSCQ-TRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDT 862
Query: 2270 ENW---------VTEGPSEDEAV---CVNCQNNSYGEKCE-SCLQGYFLLDGKCTKCQCN 2316
+W + G +A+ C+ C+ G +CE C QG+F G +CQC
Sbjct: 863 GHWGPDCSHPCNCSAGHGSCDAISGLCL-CEAGYVGPRCEQQCPQGHF-GPGCEQRCQCQ 920
Query: 2317 GHADTCNEQDGTGCPCQNNTETGTCQGSSPS 2347
H C+ G C C C+ + P+
Sbjct: 921 -HGAACDHVSG-ACTCPAGWRGTFCEHACPA 949
Score = 53.9 bits (128), Expect = 2e-06
Identities = 85/348 (24%), Positives = 111/348 (31%), Gaps = 78/348 (22%)
Query: 840 CHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPE----ECPPLCSQRLTCEDCLAN 895
C Q P C++ R + C R + +P EC P CLA
Sbjct: 149 CPPGFQGPRCQYDVDECRTHNGGCQHR-----CVNTPGSYLCECKPGFRLHTDSRTCLAI 203
Query: 896 SSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVH-SEPRCRSCDGFLTCHECLQSHEC 954
+S CA +GGC+ + + RC+ GF +
Sbjct: 204 NS-CA-----------------LGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRR 245
Query: 955 GWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLG 1014
C N + + RC G C VG L C DVDEC G
Sbjct: 246 SPCANRNGSCMHRC-----QVVRGLARCECHVGYQLAADGKA--------CEDVDECAAG 292
Query: 1015 LARCHPRATCLNTPLSYECHCQRGYQ-GDGISHCNRTCLE----------DCGHGVCSGP 1063
LA+C CLNT S++C C GY+ G C R +E C HG
Sbjct: 293 LAQC--AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTS 350
Query: 1064 PDFTCVCDLGWTSDLPPPT---PAPGPPAPRCSR---------DCGCSFHSHCRKRGPGF 1111
C C G+ D T +P C + +CGC G G
Sbjct: 351 AGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCG- 409
Query: 1112 CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNG----HGDPRRG 1155
C+D + C R G + T G C C H D RRG
Sbjct: 410 ---CED---VDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED-RRG 450
Score = 52.8 bits (125), Expect = 5e-06
Identities = 35/107 (32%), Positives = 45/107 (42%), Gaps = 21/107 (19%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDCGLQ------------ECSAYCGSHGTCASPLGPCR 192
C++ G C G C+C GW G C L ECS C ++ TC G CR
Sbjct: 1307 CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECS--CHNNSTCEPATGTCR 1364
Query: 193 CEPGFLGRACD------LHLWENQGAGWWHNVSARDPAFSARIGAAG 233
C PGF G+AC+ H QG W + + DP + AG
Sbjct: 1365 CGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
Score = 52.4 bits (124), Expect = 6e-06
Identities = 33/99 (33%), Positives = 42/99 (42%), Gaps = 27/99 (27%)
Query: 130 LLGFNASFRFSLCPGG-----------CQSHGQCQPP-GVCACEPGWGG----------- 166
L GF S +CP G C + G C P G C+C PGW G
Sbjct: 805 LPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGH 864
Query: 167 --PDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRACD 203
PDC C+ G HG+C + G C CE G++G C+
Sbjct: 865 WGPDCS-HPCNCSAG-HGSCDAISGLCLCEAGYVGPRCE 901
Score = 51.2 bits (121), Expect = 1e-05
Identities = 98/415 (23%), Positives = 134/415 (32%), Gaps = 86/415 (20%)
Query: 1818 ACNQ-SGACTWCHGACLSG-DQAHRLGCGGSPCSPMPRSPEE---CRRLRTCSECLARH- 1871
AC+ +GAC G SG +QA G G C+ M + P E C C A +
Sbjct: 1139 ACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYH 1198
Query: 1872 -PRTLQPGDGEASTPRCKWCTNCPEG-ACIGRNGSCTSEN-----DCRINQREVFWAGNC 1924
P Q P C+ C G +C G+C DC + + + NC
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 1925 SEAA-CG-AADCEQCTREGKCMWTRQFKRT--GETRRILSVQPTYDWTCFSHSLLNVSPM 1980
+ CG A C+ T C R R G + V + +C + L
Sbjct: 1259 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL------ 1312
Query: 1981 PVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGC 2040
CH SC G +HC L C G
Sbjct: 1313 -------------CHASNGSCSC----GLGWTGRHC---------------ELACPPGRY 1340
Query: 2041 GRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWG----GQDGGGRCMEGGLSGPRDGLT 2096
G +C L C+ P G C G GQ C G GL
Sbjct: 1341 GA------ACHLECSCHNNSTC---EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLC 1391
Query: 2097 CGRPGASWAFLS----CPPEDE---CANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMT 2149
+ GA +S CP C G + + CH + C C G D +T
Sbjct: 1392 WCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQR-----CDCDGGAPCDPVT 1446
Query: 2150 GLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCL 2204
GLC +C G +C + C G G +C+ C C ++C V + HC+
Sbjct: 1447 GLC--LCPPGRSGATC----NLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCV 1495
Score = 51.2 bits (121), Expect = 1e-05
Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 23/96 (23%)
Query: 132 GFNASFRFSLCPGG---------CQSHGQ---CQPP-GVCACEPGWGGPDCGLQ------ 172
GF S CP G CQ G+ C P G C+C G+ GP C +
Sbjct: 1152 GFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRY 1211
Query: 173 --ECSAYCG--SHGTCASPLGPCRCEPGFLGRACDL 204
C CG + G+C + G CRC GFLG C+L
Sbjct: 1212 GPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL 1247
Score = 50.1 bits (118), Expect = 3e-05
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 13/70 (18%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDCGLQEC-----------SAYCGSHGTCASPLGPCRC 193
C + C P G C C PGW GP C LQ C S C + GTC G C C
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCAC 1063
Query: 194 EPGFLGRACD 203
G+ G AC+
Sbjct: 1064 PEGWAGLACE 1073
Score = 50.1 bits (118), Expect = 3e-05
Identities = 27/73 (36%), Positives = 29/73 (39%), Gaps = 15/73 (20%)
Query: 144 GGCQSHGQCQP-PGVCACEPGWGGPDCG------------LQECSAYCGSHGTCASPLGP 190
GGC + G C P G C C GW G C Q CS C C G
Sbjct: 1089 GGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCS--CPPGAACHHVTGA 1146
Query: 191 CRCEPGFLGRACD 203
CRC PGF G C+
Sbjct: 1147 CRCPPGFTGSGCE 1159
Score = 49.3 bits (116), Expect = 5e-05
Identities = 43/149 (28%), Positives = 51/149 (34%), Gaps = 22/149 (14%)
Query: 67 QHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDA 126
+H + F+ LD +D D G L L G P G L
Sbjct: 502 EHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCP------EGWTGLICNETC 555
Query: 127 NYNLLGFNASFRFSLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQECSAYCGSH---- 181
+ G N SF S CQ+ G C G C C PG G +C Y G H
Sbjct: 556 PPDTFGKNCSFSCS-----CQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKK 610
Query: 182 ------GTCASPLGPCRCEPGFLGRACDL 204
G C G C C+PG GR C L
Sbjct: 611 CNCANRGRCHRLYGACLCDPGLYGRFCHL 639
Score = 47.8 bits (112), Expect = 2e-04
Identities = 80/330 (24%), Positives = 104/330 (31%), Gaps = 71/330 (21%)
Query: 2083 CMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTG 2142
C GG P C P DEC + C C + P Y C CK G
Sbjct: 133 CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSYLCECKPG 190
Query: 2143 YTM--DNMTGLCRPVCAQGCVNGSC--------VEPDHCRCHFGFV----GRNCSTECRC 2188
+ + D+ T L CA G NG C + C+C GF GR+C C
Sbjct: 191 FRLHTDSRTCLAINSCALG--NGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPC 248
Query: 2189 -NRHSEC-------AGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCR------- 2233
NR+ C G+ + + + G CE G A C
Sbjct: 249 ANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFK 308
Query: 2234 -PCHA--------------------FCRGNSHICISRKELQMSKGE----PKKYSLDPEE 2268
CHA C N+ C S S G P+ Y LD ++
Sbjct: 309 CVCHAGYELGADGRQCYRIEMEIVNSCEANNGGC-SHGCSHTSAGPLCTCPRGYELDTDQ 367
Query: 2269 IENWVTEGPSEDEAVCVN-CQNNSYGEKCESCLQGYFL-LDGKCTKCQCNGHADTCNEQD 2326
+ D C C NN G +C C GY L DG C C + + +
Sbjct: 368 -RTCIDVDDCADSPCCQQVCTNNPGGYEC-GCYAGYRLSADG----CGCEDVDECASSRG 421
Query: 2327 GTGCPCQNNTETGTCQGSS----PSDRRDC 2352
G C N + C + DRR C
Sbjct: 422 GCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 47.0 bits (110), Expect = 3e-04
Identities = 57/218 (26%), Positives = 69/218 (31%), Gaps = 62/218 (28%)
Query: 955 GWCGNEDNPTLGRCLQGDFSGPL--GGGNCSLWVGEGLGLPVALPARWAYARCP-DVDEC 1011
GW D CL + S L GG C G P P + RC DVDEC
Sbjct: 113 GWMQQPDEEG---CLSAECSASLCFHGGRCV----PGSAQPCHCPPGFQGPRCQYDVDEC 165
Query: 1012 RLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCD 1071
R C R C+NTP SY C C+ G++ + +RTCL C
Sbjct: 166 RTHNGGCQHR--CVNTPGSYLCECKPGFR---LHTDSRTCLAINS-------------CA 207
Query: 1072 LGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGS 1131
LG + GC H C T H +CRPG
Sbjct: 208 LG---------------------NGGCQHH-------------CVQLTITRHRCQCRPGF 233
Query: 1132 FGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDH 1169
G R C C + GL C+ H
Sbjct: 234 QLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECH 271
Score = 45.8 bits (107), Expect = 6e-04
Identities = 96/384 (25%), Positives = 132/384 (34%), Gaps = 85/384 (22%)
Query: 2054 CAQATQCALCLRRPHCGWCAWG--GQDGGGRCM-EGGLSGPRDGLTCGRPGASWAFLSCP 2110
C +CA L + CA G G +C+ G DG C R +
Sbjct: 283 CEDVDECAAGLAQ-----CAHGCLNTQGSFKCVCHAGYELGADGRQCYR-------IEME 330
Query: 2111 PEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLC--------RPVCAQGCVN 2162
+ C + C+ C G C+C GY +D C P C Q C N
Sbjct: 331 IVNSCEANNGGCSH--GCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTN 388
Query: 2163 GSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGV--GARDHCLLCRNHTKGSHCEQ--- 2217
C C+ G+ R + C C ECA G HC + S CE
Sbjct: 389 NP--GGYECGCYAGY--RLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCS-CEAGYR 443
Query: 2218 -------CLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIE 2270
C PL G F R HI + + EL + D EE E
Sbjct: 444 LHEDRRGCSPLEEPMVDLDGEL----PFVRPLPHIAVLQDELP-QLFQDDDVGADEEEAE 498
Query: 2271 NWVTEGPSEDEAVCVNCQNNSYGEKCE----------SCLQGYFLLDG-KCTK------C 2313
E ++ VC+ ++S+G C +CL G LDG C + C
Sbjct: 499 -LRGEHTLTEKFVCL---DDSFGHDCSLTCDDCRNGGTCLLG---LDGCDCPEGWTGLIC 551
Query: 2314 QCNGHADTCNEQDGTGCPCQN----NTETGTCQ---GSSPSDRRD-CYK-YQCAKCRESF 2364
DT + C CQN ++ TG C+ G S ++ D C K Y CR+
Sbjct: 552 NETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKC 611
Query: 2365 HGSPLGGQQCYRLISVEQECCLDP 2388
+ + G +C+RL C DP
Sbjct: 612 NCANRG--RCHRLYGA---CLCDP 630
Score = 45.4 bits (106), Expect = 8e-04
Identities = 35/110 (31%), Positives = 42/110 (38%), Gaps = 20/110 (18%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDCGLQEC-----------SAYCGSHGTCASPLGPCRC 193
CQ+ G C P G CAC GW G C +EC S C + G C G C C
Sbjct: 1048 CQNGGTCDPVSGHCACPEGWAGLACE-KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLC 1106
Query: 194 EPGFLGRACDLHLWENQGAGWWHNVSARD---PAFSARIGAAGAFLSPPG 240
G+ G C GW+ A+ P +A GA PPG
Sbjct: 1107 PAGWTGDKCQSPCLR----GWFGEACAQRCSCPPGAACHHVTGACRCPPG 1152
Score = 44.7 bits (104), Expect = 0.001
Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 18/94 (19%)
Query: 133 FNASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDC-----------GLQECSAYCGSH 181
F + S GG HG G C C PG G DC G QE C
Sbjct: 736 FGVNCSSSCSCGGAPCHGVT---GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHA 792
Query: 182 GTCASPLGPCRCEPGFLGRACDLHLWENQGAGWW 215
C G C C PGF+G C + AGW+
Sbjct: 793 ARCDPETGACLCLPGFVGSRCQ----DVCPAGWY 822
Score = 41.6 bits (96), Expect = 0.011
Identities = 21/68 (30%), Positives = 26/68 (38%), Gaps = 11/68 (16%)
Query: 146 CQSHGQCQP-PGVCACEPGWGGPDCGLQ--------ECSAYC--GSHGTCASPLGPCRCE 194
C C P G+C C PG G C L C+ +C G C G C C
Sbjct: 1436 CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCV 1495
Query: 195 PGFLGRAC 202
G++G C
Sbjct: 1496 DGYMGPTC 1503
Score = 40.0 bits (92), Expect = 0.032
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query: 145 GCQSHGQCQP-PGVCACEPGWGGPDCGLQ----------ECSAYCGSHGTCASPLGPCRC 193
GC C P G C C PG G C E + C + G C + G C C
Sbjct: 1263 GCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSC 1322
Query: 194 EPGFLGRACDL 204
G+ GR C+L
Sbjct: 1323 GLGWTGRHCEL 1333
Score = 38.9 bits (89), Expect = 0.071
Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 12/73 (16%)
Query: 143 PGGCQS-HGQCQP-PGVCACEPGWGGPDCGLQ----------ECSAYCGSHGTCASPLGP 190
P C + HG C G+C CE G+ GP C Q E C C G
Sbjct: 872 PCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA 931
Query: 191 CRCEPGFLGRACD 203
C C G+ G C+
Sbjct: 932 CTCPAGWRGTFCE 944
Score = 37.7 bits (86), Expect = 0.16
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 11/69 (15%)
Query: 146 CQSHGQCQPP-GVCACEPGWGGPDC------GLQE--CSAYCG-SHGTCASPL-GPCRCE 194
C ++ C+P G C C PG+ G C G C C HG P+ G C C
Sbjct: 1350 CHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCP 1409
Query: 195 PGFLGRACD 203
GF G C+
Sbjct: 1410 AGFHGHFCE 1418
Score = 37.4 bits (85), Expect = 0.21
Identities = 24/64 (37%), Positives = 26/64 (40%), Gaps = 8/64 (12%)
Query: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGR 200
LCP G H C+ CEPG G C Q C C C G C C PG G
Sbjct: 1407 LCPAGFHGHF-CER----GCEPGSFGEGCH-QRCD--CDGGAPCDPVTGLCLCPPGRSGA 1458
Query: 201 ACDL 204
C+L
Sbjct: 1459 TCNL 1462
Score = 37.0 bits (84), Expect = 0.27
Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 15/71 (21%)
Query: 146 CQSHGQCQPP-GVCACEPG------------WG-GPDCGLQECSAYCGSHGTCASPLGPC 191
C + G+C G C C+PG W GP C +EC +C G C
Sbjct: 613 CANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCS-EECQCVQPHTQSCDKRDGSC 671
Query: 192 RCEPGFLGRAC 202
C+ GF G C
Sbjct: 672 SCKAGFRGERC 682
Score = 34.3 bits (77), Expect = 1.8
Identities = 25/92 (27%), Positives = 34/92 (36%), Gaps = 18/92 (19%)
Query: 1321 WEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMA 1380
W +A ++ C GG CVP A C CP G+ GP C+
Sbjct: 114 WMQQPDEEGCLSAECSASLCFHGG--------RCVP----GSAQPCHCPPGFQGPRCQYD 161
Query: 1381 LCPENCNAHTGA--GTCNQSLG--VCICAEGF 1408
+ + C H G C + G +C C GF
Sbjct: 162 V--DECRTHNGGCQHRCVNTPGSYLCECKPGF 191
Score = 32.3 bits (72), Expect = 6.7
Identities = 22/52 (42%), Positives = 22/52 (42%), Gaps = 6/52 (11%)
Query: 157 VCACEPGW-GGPD---CGLQECSAYCGSHGTCASP--LGPCRCEPGFLGRAC 202
V C GW PD C ECSA HG P PC C PGF G C
Sbjct: 107 VLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRC 158
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 90.1 bits (222), Expect = 3e-17
Identities = 112/448 (25%), Positives = 143/448 (31%), Gaps = 94/448 (20%)
Query: 1033 CHCQRGYQG-------------DGI--------SHCNRTCLEDCGHGVCSGPPDFTCVCD 1071
C C +GY G DGI C+ E HGVC T
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTT--G 766
Query: 1072 LGWTSDLPPPTPAPGPPAPRCSRDCGC---------SFHSHCRKRGPGFCDECQDWTWGE 1122
+ LP P P + C C S H CD C G
Sbjct: 767 VHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 1123 HCERCRPGSFGNAT-GSRGCRPCQCNGHGDPRR-GHCDNLSGLCF-CQDHTEGAHCQLCS 1179
CERC G +GN T C PC C+G+ DP GHCD+++G C C +T+GAHC+ C+
Sbjct: 827 WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCA 886
Query: 1180 PGYYGDPRAGGSCFR-ECGGRALLTNVSSVALG----SRRVGGL-----------LPPGG 1223
G+YGD +C EC + + V + G V G L G
Sbjct: 887 DGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGH 946
Query: 1224 GAARAGPGLSYCVWVVSATEELQPCAPGTL------CPPLTLTFSPDSSTPCTLSYVLAF 1277
G ++ V E C PG C + S TPC
Sbjct: 947 GCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDC------ 1000
Query: 1278 DGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGS 1337
P +T D C + G HW G++A VG
Sbjct: 1001 ---PHTQNT----CDPETGECVCPPHTQGVKCEECEDG----HW--------GYDAEVGC 1041
Query: 1338 ARCGSGGPGSC-----PVPQECVPQDGAAGAGLCRCPQGWAG-PHCRMALCP------EN 1385
C GS V C + G +C G+ P C C +
Sbjct: 1042 QACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDA 1101
Query: 1386 CNAHTGAGTCNQSLGVCICAEGFGGPDC 1413
CN G C + G C C E GP C
Sbjct: 1102 CNLEQGLCGCVEETGACPCKENVFGPQC 1129
Score = 78.6 bits (192), Expect = 8e-14
Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 48/270 (17%)
Query: 2137 CSCKTGYTMDNMTGLCR---------PVCAQGCVNGSCVEPDHCRCHFGFVGR-----NC 2182
C+C +N + C CA G C RC G+ G
Sbjct: 791 CACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCE-----RCADGYYGNPTVPGES 845
Query: 2183 STECRCNRHSECAGVGARD----HCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAF 2238
C C+ + + + G D CL C +T G+HCE+C F G AV CR C
Sbjct: 846 CVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECH 905
Query: 2239 CRGNSHICISRKELQMSKGEPK------------KYSLDPE--------EIENWVTEGPS 2278
+G SH + E + +P Y LD + V++G
Sbjct: 906 VKG-SHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDG-C 963
Query: 2279 EDEAVCVNCQNNSYGEKCESCLQGYFLL-DGKCTKCQCNGHADTCNEQDGTGCPCQNNTE 2337
DE C +C G++C+ C G++ DG CT C C +TC+ + G C C +T+
Sbjct: 964 TDEGQC-HCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGE-CVCPPHTQ 1021
Query: 2338 TGTCQGSSPSDRRDCYKYQCAKCRESFHGS 2367
C+ + C C S GS
Sbjct: 1022 GVKCEECEDGHWGYDAEVGCQACNCSLVGS 1051
Score = 75.1 bits (183), Expect = 9e-13
Identities = 58/236 (24%), Positives = 84/236 (35%), Gaps = 73/236 (30%)
Query: 2169 DHCRCHFGFVGRNCST------------------ECRCNRHS-ECAGVGARDHCLLCRNH 2209
+HC C G+ G +C + C C+ H+ EC G C+ C ++
Sbjct: 707 EHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGV---CIACAHN 763
Query: 2210 TKGSHCEQCLPLFVGSAVGG--GTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPE 2267
T G HCEQCLP F G G G C+PC P + +
Sbjct: 764 TTGVHCEQCLPGFYGEPSRGTPGDCQPCAC---------------------PLTIASNNF 802
Query: 2268 EIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF----LLDGKCTKCQCNGHADT-- 2321
+ +G DE VC C G CE C GY+ + C C C+G+ D
Sbjct: 803 SPTCHLNDG---DEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSE 859
Query: 2322 ---CNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQC 2374
C+ G C NT+ C+ +C + F+G + + C
Sbjct: 860 AGHCDSVTGECLKCLGNTDGAHCE----------------RCADGFYGDAVTAKNC 899
Score = 69.3 bits (168), Expect = 5e-11
Identities = 55/157 (35%), Positives = 67/157 (42%), Gaps = 25/157 (15%)
Query: 1052 LEDCGHGVCS-GPPDFTCV-CDLGWTSDLPPPTPAPGP-PAPRCSRDCGCSFHSHCRKRG 1108
LE+C VC G F+C C G+ P GP P C C+ HS
Sbjct: 1359 LENC---VCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPN 1415
Query: 1109 PGFCDECQDWTWGEHCERCRPGSFGNATGSRG-CRPCQCNGHGDPRRGHCDNLSGLCFCQ 1167
G C C D T G+HC+ C G +G TGS C C C H P + S C +
Sbjct: 1416 TGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACP-HSPPA-----SFSPTCVLE 1469
Query: 1168 -DHT----------EGAHCQLCSPGYYGDPRA-GGSC 1192
DH EG HC+ CS YYG+P+ GGSC
Sbjct: 1470 GDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSC 1506
Score = 67.4 bits (163), Expect = 2e-10
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
Query: 1112 CDECQDWTWGEHCERCRPGSFGNA-TGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHT 1170
CD C G+HCERC +GN T C+ C CN HG G CD SG C C+
Sbjct: 1476 CDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHGSVH-GDCDRTSGQCVCRLGA 1534
Query: 1171 EGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSV--ALGSRRVGGLLP 1220
G C C P + SC EC G LL ++ + A+ S + G++P
Sbjct: 1535 SGLRCDECEPRHILMETDCVSCDDECVG-VLLNDLDEIGDAVLSLNLTGIIP 1585
Score = 65.1 bits (157), Expect = 9e-10
Identities = 85/353 (24%), Positives = 112/353 (31%), Gaps = 78/353 (22%)
Query: 1114 ECQDWTWGEHCERCRPGSF---GNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCF-CQDH 1169
EC G CE C G + G G C+PC+C+GH C N+ G+C C +
Sbjct: 710 ECPQGYTGTSCESCLSGYYRVDGILFGGI-CQPCECHGHA----AEC-NVHGVCIACAHN 763
Query: 1170 TEGAHCQLCSPGYYGDPRAG--GSCFRECGGRALLTNVSSVAL----GSRRVGGLLPPGG 1223
T G HC+ C PG+YG+P G G C + +N S G V PG
Sbjct: 764 TTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGY 823
Query: 1224 GAARAGPGLSYCVWVVSATEEL--QPCAPGTLCPPLTLTFSPDSSTPCTLSYVLA----- 1276
A W + P PG C P + + D S V
Sbjct: 824 SGA----------WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKC 873
Query: 1277 ------------FDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEAN 1324
DGF G + ++ A C + +GL
Sbjct: 874 LGNTDGAHCERCADGF-----YGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVT 928
Query: 1325 GSSS-------WGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHC 1377
G +G ++ G C GS DG G C C G AG C
Sbjct: 929 GQQCDQCLHGYYGLDSGHGCRPCNCSVAGSV--------SDGCTDEGQCHCVPGVAGKRC 980
Query: 1378 RM-----------ALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDG 1419
+ P +C HT TC+ G C+C G C DG
Sbjct: 981 DRCAHGFYAYQDGSCTPCDC-PHT-QNTCDPETGECVCPPHTQGVKCEECEDG 1031
Score = 65.1 bits (157), Expect = 9e-10
Identities = 75/276 (27%), Positives = 93/276 (33%), Gaps = 70/276 (25%)
Query: 934 PRCRSCDGF-LTCHECLQSHECGWC-----GNEDNPTLG--RCLQGDFSG---PLGGGNC 982
P C DG + C C + WC G NPT+ C+ D SG P G+C
Sbjct: 804 PTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHC 863
Query: 983 SLWVGEGL-------GLPVALPARWAYARCPDVDECRLGLARCHPR----ATC-LNTPLS 1030
GE L G A Y CR CH + A C L T L
Sbjct: 864 DSVTGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRA--CECHVKGSHSAVCHLETGL- 920
Query: 1031 YECHCQRGYQGDGISHCNRTCLE-DCGHGVCSGPPDFTCVCDL-GWTSDLPPPTPAPGPP 1088
C C+ G C D GHG C C C + G SD
Sbjct: 921 --CDCKPNVTGQQCDQCLHGYYGLDSGHG-CR-----PCNCSVAGSVSD----------- 961
Query: 1089 APRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNG 1148
GC+ C C G+ C+RC G + GS C PC C
Sbjct: 962 --------GCTDEGQCH---------CVPGVAGKRCDRCAHGFYAYQDGS--CTPCDC-- 1000
Query: 1149 HGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYG 1184
+ CD +G C C HT+G C+ C G++G
Sbjct: 1001 --PHTQNTCDPETGECVCPPHTQGVKCEECEDGHWG 1034
Score = 64.7 bits (156), Expect = 1e-09
Identities = 96/406 (23%), Positives = 117/406 (28%), Gaps = 97/406 (23%)
Query: 825 VLVPTLCPLCEEHRDCHACTQDPFC-EWHQSTSRKGDAACSRRGRGRGALKSPEECPPLC 883
+L +C CE H C C +T+ C G + +P +C P C
Sbjct: 733 ILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPGDCQP-C 791
Query: 884 SQRLTCED------CLANSSQ---CAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEP 934
+ LT C N C WC Y C D + P
Sbjct: 792 ACPLTIASNNFSPTCHLNDGDEVVCDWCAPG------------YSGAWCERCADGYYGNP 839
Query: 935 R-----CRSCDGFLTCHECLQSHECGWC-----------GNEDNPTLGRCLQGDFSGPLG 978
C CD C + E G C GN D RC G + +
Sbjct: 840 TVPGESCVPCD----CSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGFYGDAVT 895
Query: 979 GGNCSLWVGEGLGLPVALPARWAYARCPDVDECRL--GLARCHPRATCLNTPLSYEC-HC 1035
NC G A+ C L GL C P T +C C
Sbjct: 896 AKNCRACECHVKGSHSAV--------------CHLETGLCDCKPNVT------GQQCDQC 935
Query: 1036 QRGYQGDGISHCNRTCLEDCGHGVCSGPPDF-TCVCDLGWTSDLPPPTPAPGPPAPRCSR 1094
GY G H R C V G D C C PG RC R
Sbjct: 936 LHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHC-------------VPGVAGKRCDR 982
Query: 1095 --------------DCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG 1140
C C + G C C T G CE C G +G G
Sbjct: 983 CAHGFYAYQDGSCTPCDCPHTQNTCDPETGEC-VCPPHTQGVKCEECEDGHWGY-DAEVG 1040
Query: 1141 CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDP 1186
C+ C C+ G CD ++G C C+ G C CS GY P
Sbjct: 1041 CQACNCSLVGSTHH-RCDVVTGHCQCKSKFGGRACDQCSLGYRDFP 1085
Score = 56.2 bits (134), Expect = 4e-07
Identities = 38/162 (23%), Positives = 58/162 (35%), Gaps = 41/162 (25%)
Query: 2206 CRNHTKGSHCEQCLPLF------VGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEP 2259
C ++T G C +C P + G+ G TC C+ C + C + + K
Sbjct: 292 CEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACN--CHNKAKDCYYDESVAKQK--- 346
Query: 2260 KKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-------LLDGKCTK 2312
++ T G VC+NC N+ G CE+C+ GY+ D C
Sbjct: 347 ----------KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRP 396
Query: 2313 CQCNG-------------HADTCNEQDGTGCPCQNNTETGTC 2341
C C+ H+D N + CPC+ C
Sbjct: 397 CNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKC 438
Score = 55.8 bits (133), Expect = 6e-07
Identities = 39/126 (30%), Positives = 52/126 (41%), Gaps = 22/126 (17%)
Query: 1082 TPAPGPPAPRCSRDCGCSFHSHCRK----------RGPGFCDECQDWTWGEHCERCRPGS 1131
+P P C+ D S S C K + PG C C++ GE C+RC+ G
Sbjct: 387 SPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCP-CKEGYTGEKCDRCQLGY 445
Query: 1132 FGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYG----DPR 1187
T C C CN G C +G C C+++ EG C C PG+Y +PR
Sbjct: 446 KDYPT----CVSCGCNPVGSASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPR 498
Query: 1188 AGGSCF 1193
CF
Sbjct: 499 GCSECF 504
Score = 55.1 bits (131), Expect = 1e-06
Identities = 60/244 (24%), Positives = 88/244 (36%), Gaps = 57/244 (23%)
Query: 2126 QNCHDQPHGYECSCKTGYTMDNMTGLCRPV--CAQGCVNGSCVEPDHCRCHFGFVGRNCS 2183
Q C HGY Y +D+ G CRP G V+ C + C C G G+ C
Sbjct: 930 QQCDQCLHGY-------YGLDSGHG-CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD 981
Query: 2184 --------------TECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGG 2229
T C C H++ C+ C HT+G CE+C G
Sbjct: 982 RCAHGFYAYQDGSCTPCDCP-HTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDAEV 1039
Query: 2230 GTCRPCHAFCRGNSHI--------CISRKEL------QMSKGEPKKYSLDPEEIENWVTE 2275
G C+ C+ G++H C + + Q S G P + + T
Sbjct: 1040 G-CQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTS 1098
Query: 2276 GPS-----------EDEAVCVNCQNNSYGEKCESCLQGYFLLDGK----CTKCQCNGHAD 2320
G + E+ C C+ N +G +C C +G F L C+ C C+G +
Sbjct: 1099 GDACNLEQGLCGCVEETGACP-CKENVFGPQCNECREGTFALRADNPLGCSPCFCSGLSH 1157
Query: 2321 TCNE 2324
C+E
Sbjct: 1158 LCSE 1161
Score = 54.7 bits (130), Expect = 1e-06
Identities = 46/188 (24%), Positives = 61/188 (32%), Gaps = 35/188 (18%)
Query: 2186 CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGT-CRPCHAFCRGNSH 2244
C CN HS+ CL C ++T G HC+ C + G G + C C
Sbjct: 1403 CSCNNHSDTCDPNT-GKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC------- 1454
Query: 2245 ICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF 2304
P +S V EG + + C C G+ CE C Y+
Sbjct: 1455 ----------PHSPPASFS------PTCVLEG--DHDFRCDACLLGYEGKHCERCSSSYY 1496
Query: 2305 ----LLDGKCTKCQCNGHADTCNEQDGTG--CPCQNNTETGTCQGSSPSDRRDCYKYQCA 2358
G C KC CN H + D T C C+ C P R + C
Sbjct: 1497 GNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEP--RHILMETDCV 1554
Query: 2359 KCRESFHG 2366
C + G
Sbjct: 1555 SCDDECVG 1562
Score = 46.6 bits (109), Expect = 3e-04
Identities = 36/149 (24%), Positives = 54/149 (36%), Gaps = 27/149 (18%)
Query: 2203 CLLCRNHTKGSHCEQCLPLFVG----SAVGGGTCRPCHAFCRGN-SHICISRKELQMSKG 2257
C+ C +T G +CE C+ + S CRPC+ G+ S +CI
Sbjct: 361 CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIK--------- 411
Query: 2258 EPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNG 2317
+++ + + G + C + GEKC+ C GY C C CN
Sbjct: 412 ---------DDLHSDLHNGKQPGQCPC---KEGYTGEKCDRCQLGYKDYP-TCVSCGCNP 458
Query: 2318 HADTCNEQDGTGCPCQNNTETGTCQGSSP 2346
+E C C+ N E C P
Sbjct: 459 VGSASDEPCTGPCVCKENVEGKACDRCKP 487
Score = 42.7 bits (99), Expect = 0.005
Identities = 47/169 (27%), Positives = 61/169 (36%), Gaps = 33/169 (19%)
Query: 2108 SCPPEDECANGHHDCN-ETQNCHDQPH--GYECS-CKTGYT-MDNMTGLCRPVCAQ-GCV 2161
SC P D C + + C+ ET C PH G +C C+ G+ D G C+ G
Sbjct: 994 SCTPCD-CPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGST 1052
Query: 2162 NGSC-VEPDHCRCHFGFVGRNCS---------TEC-------------RCNRHSECAGVG 2198
+ C V HC+C F GR C +C CN G
Sbjct: 1053 HHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCV 1112
Query: 2199 ARDHCLLCRNHTKGSHCEQCLP-LFVGSAVGGGTCRPCHAFCRGNSHIC 2246
C+ + G C +C F A C PC FC G SH+C
Sbjct: 1113 EETGACPCKENVFGPQCNECREGTFALRADNPLGCSPC--FCSGLSHLC 1159
Score = 41.2 bits (95), Expect = 0.014
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 14/71 (19%)
Query: 2284 CVNCQNNSYGEKCESCLQGYFL-------------LDGKCTKCQCNGHADTCNEQDGTGC 2330
CV C + G C+ C GY L C C CN H+DTC+ G
Sbjct: 1362 CV-CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 2331 PCQNNTETGTC 2341
C +NT C
Sbjct: 1421 NCGDNTAGDHC 1431
Score = 39.7 bits (91), Expect = 0.042
Identities = 36/155 (23%), Positives = 51/155 (32%), Gaps = 36/155 (23%)
Query: 2127 NCHDQPHGYEC-SCKTGYTMDNMTGL-----CRPVCAQ--GCVNGSCV------------ 2166
NC G C +C GY + CRP G ++ C+
Sbjct: 363 NCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGK 422
Query: 2167 EPDHCRCHFGFVGRNCS------------TECRCNRHSECAGVGARDHCLLCRNHTKGSH 2214
+P C C G+ G C C CN + C+ C+ + +G
Sbjct: 423 QPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCV-CKENVEGKA 481
Query: 2215 CEQCLPLFVG-SAVGGGTCRPCHAFCRGNSHICIS 2248
C++C P F C C FC G S +C S
Sbjct: 482 CDRCKPGFYNLKEKNPRGCSEC--FCFGVSDVCSS 514
Score = 38.9 bits (89), Expect = 0.071
Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 25/93 (26%)
Query: 1114 ECQDWTWGEHCERCRPGSF------GNATGSRGCRPCQCNGHGDPRRGHCDNL------- 1160
+C+ T GE C RC PG G + C C C H + + D
Sbjct: 291 QCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC--HNKAKDCYYDESVAKQKKS 348
Query: 1161 ---------SGLCF-CQDHTEGAHCQLCSPGYY 1183
G+C C +T G +C+ C GYY
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYY 381
Score = 37.0 bits (84), Expect = 0.27
Identities = 29/90 (32%), Positives = 33/90 (36%), Gaps = 18/90 (20%)
Query: 132 GFNASFRFSLCPGGC-QSHGQCQPP-GVCACEPGWGGPDC--------------GLQ--E 173
GF A S P C + C P G C C P G C G Q
Sbjct: 986 GFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACN 1045
Query: 174 CSAYCGSHGTCASPLGPCRCEPGFLGRACD 203
CS +H C G C+C+ F GRACD
Sbjct: 1046 CSLVGSTHHRCDVVTGHCQCKSKFGGRACD 1075
Score = 37.0 bits (84), Expect = 0.27
Identities = 44/197 (22%), Positives = 65/197 (32%), Gaps = 66/197 (33%)
Query: 2191 HSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGT----------CRPCHAFCR 2240
H E ++C+ C T G C+ C P + + G+ C PC C
Sbjct: 1350 HPEEEVASLLENCV-CPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCS--CN 1406
Query: 2241 GNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCL 2300
+S C DP + C+NC +N+ G+ C+ C
Sbjct: 1407 NHSDTC------------------DP-------------NTGKCLNCGDNTAGDHCDVCT 1435
Query: 2301 QGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETG---TCQGSSPSDRR------D 2351
GY+ GK T G A C C C ++ TC D R
Sbjct: 1436 SGYY---GKVT-----GSASDC-----ALCACPHSPPASFSPTCVLEGDHDFRCDACLLG 1482
Query: 2352 CYKYQCAKCRESFHGSP 2368
C +C S++G+P
Sbjct: 1483 YEGKHCERCSSSYYGNP 1499
Score = 35.8 bits (81), Expect = 0.60
Identities = 25/74 (33%), Positives = 27/74 (36%), Gaps = 15/74 (20%)
Query: 1360 AAGAGLCRCPQGWAGPHCRMALCP-------------ENCNAHTGAGTCNQSLGVCI-CA 1405
AA C CPQG+ G C L + C H A CN GVCI CA
Sbjct: 703 AADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACA 761
Query: 1406 EGFGGPDCATKLDG 1419
G C L G
Sbjct: 762 HNTTGVHCEQCLPG 775
Score = 34.3 bits (77), Expect = 1.8
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 15/62 (24%)
Query: 155 PGVCACEPGWGGPDCGLQECSAYCGSHGTCAS----PLG---------PCRCEPGFLGRA 201
PG C C+ G+ G C C + TC S P+G PC C+ G+A
Sbjct: 424 PGQCPCKEGYTGEKC--DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481
Query: 202 CD 203
CD
Sbjct: 482 CD 483
Score = 32.3 bits (72), Expect = 6.7
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 15/63 (23%)
Query: 156 GVCACEPGWGGPDC--------------GLQECS-AYCGSHGTCASPLGPCRCEPGFLGR 200
G+C C+P G C G + C+ + GS + G C C PG G+
Sbjct: 919 GLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGK 978
Query: 201 ACD 203
CD
Sbjct: 979 RCD 981
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 89.4 bits (220), Expect = 5e-17
Identities = 62/180 (34%), Positives = 78/180 (43%), Gaps = 28/180 (15%)
Query: 1016 ARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCV-CDLGW 1074
AR P TC+ C+CQ G D + DC G PD C C +G+
Sbjct: 405 ARLGPFGTCI------PCNCQGGGACDPDTG-------DCYSG--DENPDIECADCPIGF 449
Query: 1075 TSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGN 1134
+D P P P P C CS + C+ C G CE C G FG+
Sbjct: 450 YND--PHDPRSCKPCP-CHNGFSCSVMPETEEV---VCNNCPPGVTGARCELCADGYFGD 503
Query: 1135 ATGSRG----CRPCQCNGHGDPRR-GHCDNLSGLCF-CQDHTEGAHCQLCSPGYYGDPRA 1188
G G C+PCQCN + DP G+CD L+G C C +T G +C C GY+GDP A
Sbjct: 504 PFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
Score = 66.2 bits (160), Expect = 4e-10
Identities = 38/92 (41%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 1093 SRDCGCSFHSHCRKRGPGF-CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGD 1151
SR C H R+ G GF C C D T G HCE+C+ G + + R C PC CN G
Sbjct: 34 SRQCIFDRELH-RQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNCNSKGS 91
Query: 1152 PRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
CDN SG C C+ GA C C PG++
Sbjct: 92 -LSARCDN-SGRCSCKPGVTGARCDRCLPGFH 121
Score = 52.4 bits (124), Expect = 6e-06
Identities = 47/189 (24%), Positives = 73/189 (38%), Gaps = 29/189 (15%)
Query: 1006 PDVDECRLGLARCHPRATCLNTPLSY-----------ECHCQRGYQGDGISHCNRTCLED 1054
PD +C G +P C + P+ + C C G+ + +
Sbjct: 426 PDTGDCYSGDE--NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN 483
Query: 1055 CGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAP----RCSRDCGCSFHSHCRKRGPG 1110
C GV + +C G+ D P GP P +C+ + S +C R G
Sbjct: 484 CPPGVTGARCE---LCADGYFGD---PFGEHGPVRPCQPCQCNNNVDPSASGNC-DRLTG 536
Query: 1111 FCDECQDWTWGEHCERCRPGSFGNATG---SRGCRPCQCNGHGDPRRGHCDNLSGLCFCQ 1167
C +C T G +C++C+ G FG+ + CR C CN G G C + G C C+
Sbjct: 537 RCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG-CRS-DGTCVCK 594
Query: 1168 DHTEGAHCQ 1176
G +C+
Sbjct: 595 PGFGGPNCE 603
Score = 50.8 bits (120), Expect = 2e-05
Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 52/179 (29%)
Query: 2186 CRCNRHS-EC---------AGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPC 2235
C CN S +C G G R CL C ++T G HCE+C F C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFR--CLNCNDNTDGIHCEKCKNGFYRHR-ERDRCLPC 84
Query: 2236 HAFCRG-------NSHICISRKELQMSKGE---------------------PKKYSLDPE 2267
+ +G NS C + + ++ + K DP
Sbjct: 85 NCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPA 144
Query: 2268 EIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG----KCTKCQCNGHADTC 2322
I GP D CV C+ GE+C+ C GY+ LDG CT+C C GH+ +C
Sbjct: 145 GI-----AGPC-DAGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 50.8 bits (120), Expect = 2e-05
Identities = 60/247 (24%), Positives = 83/247 (33%), Gaps = 59/247 (23%)
Query: 2141 TGYTMDNMTGL-CRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGA 2199
TGY +DN+T + RPV + C C G+ G+ C +C + A +G
Sbjct: 357 TGY-IDNVTLISARPVSG-----APAPWVEQCICPVGYKGQFCQ-DCASGYKRDSARLGP 409
Query: 2200 RDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRG---NSHICISRKELQMSK 2256
C+ C +C+ GGG C P C N I + +
Sbjct: 410 FGTCIPC-------NCQ-----------GGGACDPDTGDCYSGDENPDIECADCPIGFYN 451
Query: 2257 GEPKKYSLDPEEIENWVTEG--PSEDEAVCVNCQNNSYGEKCESCLQGYFLLD------- 2307
S P N + P +E VC NC G +CE C GYF
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 2308 GKCTKCQCNGHAD-----TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRE 2362
C CQCN + D C+ G C +NT C +C+
Sbjct: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA----------------GIYCDQCKA 555
Query: 2363 SFHGSPL 2369
+ G PL
Sbjct: 556 GYFGDPL 562
Score = 49.7 bits (117), Expect = 4e-05
Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 18/121 (14%)
Query: 1104 CRKRGPGFCD-ECQDWTWGEH-----CERCRPGSFGNATGSRGCRPCQC-NGHG-----D 1151
C +G G CD + D G+ C C G + + R C+PC C NG +
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPE 475
Query: 1152 PRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALG 1211
C+N C GA C+LC+ GY+GDP R C NV A G
Sbjct: 476 TEEVVCNN------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 1212 S 1212
+
Sbjct: 530 N 530
Score = 43.9 bits (102), Expect = 0.002
Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 46/178 (25%)
Query: 2215 CEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVT 2274
C C L + +A C C G S CI +EL G +
Sbjct: 8 CCLCFSLLLPAARATSRREVCD--CNGKSRQCIFDRELHRQTGNGFR------------- 52
Query: 2275 EGPSEDEAVCVNCQNNSYGEKCESCLQGYF--LLDGKCTKCQCNGHADTCNEQDGTG-CP 2331
C+NC +N+ G CE C G++ +C C CN D +G C
Sbjct: 53 ---------CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCS 103
Query: 2332 CQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHG-SPLGGQQCYRLISVEQECCLDP 2388
C+ TG +C +C FH + G Q RL+ + +C DP
Sbjct: 104 CKPGV-TGA---------------RCDRCLPGFHMLTDAGCTQDQRLL--DSKCDCDP 143
Score = 42.4 bits (98), Expect = 0.006
Identities = 53/215 (24%), Positives = 77/215 (35%), Gaps = 44/215 (20%)
Query: 2060 CALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPED-ECANG 2118
C + + C CA G + R G P C G +C P+ +C +G
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSARLGPFGTCIP-----CNCQGGG----ACDPDTGDCYSG 434
Query: 2119 HHDCNETQNCHDQPHGY-----------ECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVE 2167
D N C D P G+ C C G++ M VC C G V
Sbjct: 435 --DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC-NNCPPG--VT 489
Query: 2168 PDHCR-CHFGFVG---------RNCSTECRCNRHSECAGVGARDH----CLLCRNHTKGS 2213
C C G+ G R C C+CN + + + G D CL C ++T G
Sbjct: 490 GARCELCADGYFGDPFGEHGPVRPCQP-CQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
Query: 2214 HCEQCLPLFVGSAVG---GGTCRPCHAFCRGNSHI 2245
+C+QC + G + CR C+ G+ +
Sbjct: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
Score = 34.7 bits (78), Expect = 1.3
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 3/36 (8%)
Query: 143 PGGCQSHGQCQPPGVCACEPGWGGPDC--GLQECSA 176
P G + G C+ G C C+PG+GGP+C G C A
Sbjct: 577 PMGSEPVG-CRSDGTCVCKPGFGGPNCEHGAFSCPA 611
Score = 33.9 bits (76), Expect = 2.3
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 8/59 (13%)
Query: 1361 AGAGLCRCPQGWAG------PHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDC 1413
AG +C G+ G P + C NCN +S G C+C GFGGP+C
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRAC--NCNPMGSEPVGCRSDGTCVCKPGFGGPNC 602
Score = 32.7 bits (73), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 6/46 (13%)
Query: 1144 CQCNGHGDP----RRGHCDNLSGL-CF-CQDHTEGAHCQLCSPGYY 1183
C CNG R H +G C C D+T+G HC+ C G+Y
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY 73
Score = 32.0 bits (71), Expect = 8.7
Identities = 29/127 (22%), Positives = 39/127 (30%), Gaps = 8/127 (6%)
Query: 1816 PEACNQSGACTWCHGACLSGDQAHRLGCG-------GSPCSPMPRSPEECRRLRTCSECL 1868
P C GAC G C SGD+ + C P P P C +CS
Sbjct: 415 PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
Query: 1869 ARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQR-EVFWAGNCSEA 1927
+ RC+ C + G G +G C+ N + +GNC
Sbjct: 475 ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL 534
Query: 1928 ACGAADC 1934
C
Sbjct: 535 TGRCLKC 541
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 89.4 bits (220), Expect = 5e-17
Identities = 62/180 (34%), Positives = 78/180 (43%), Gaps = 28/180 (15%)
Query: 1016 ARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCV-CDLGW 1074
AR P TC+ C+CQ G D + DC G PD C C +G+
Sbjct: 405 ARLGPFGTCI------PCNCQGGGACDPDTG-------DCYSG--DENPDIECADCPIGF 449
Query: 1075 TSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGN 1134
+D P P P P C CS + C+ C G CE C G FG+
Sbjct: 450 YND--PHDPRSCKPCP-CHNGFSCSVMPETEEV---VCNNCPPGVTGARCELCADGYFGD 503
Query: 1135 ATGSRG----CRPCQCNGHGDPRR-GHCDNLSGLCF-CQDHTEGAHCQLCSPGYYGDPRA 1188
G G C+PCQCN + DP G+CD L+G C C +T G +C C GY+GDP A
Sbjct: 504 PFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLA 563
Score = 66.2 bits (160), Expect = 4e-10
Identities = 38/92 (41%), Positives = 46/92 (50%), Gaps = 5/92 (5%)
Query: 1093 SRDCGCSFHSHCRKRGPGF-CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGD 1151
SR C H R+ G GF C C D T G HCE+C+ G + + R C PC CN G
Sbjct: 34 SRQCIFDRELH-RQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDR-CLPCNCNSKGS 91
Query: 1152 PRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
CDN SG C C+ GA C C PG++
Sbjct: 92 -LSARCDN-SGRCSCKPGVTGARCDRCLPGFH 121
Score = 52.4 bits (124), Expect = 6e-06
Identities = 47/189 (24%), Positives = 73/189 (38%), Gaps = 29/189 (15%)
Query: 1006 PDVDECRLGLARCHPRATCLNTPLSY-----------ECHCQRGYQGDGISHCNRTCLED 1054
PD +C G +P C + P+ + C C G+ + +
Sbjct: 426 PDTGDCYSGDE--NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNN 483
Query: 1055 CGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAP----RCSRDCGCSFHSHCRKRGPG 1110
C GV + +C G+ D P GP P +C+ + S +C R G
Sbjct: 484 CPPGVTGARCE---LCADGYFGD---PFGEHGPVRPCQPCQCNNNVDPSASGNC-DRLTG 536
Query: 1111 FCDECQDWTWGEHCERCRPGSFGNATG---SRGCRPCQCNGHGDPRRGHCDNLSGLCFCQ 1167
C +C T G +C++C+ G FG+ + CR C CN G G C + G C C+
Sbjct: 537 RCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVG-CRS-DGTCVCK 594
Query: 1168 DHTEGAHCQ 1176
G +C+
Sbjct: 595 PGFGGPNCE 603
Score = 50.8 bits (120), Expect = 2e-05
Identities = 51/179 (28%), Positives = 69/179 (38%), Gaps = 52/179 (29%)
Query: 2186 CRCNRHS-EC---------AGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPC 2235
C CN S +C G G R CL C ++T G HCE+C F C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFR--CLNCNDNTDGIHCEKCKNGFYRHR-ERDRCLPC 84
Query: 2236 HAFCRG-------NSHICISRKELQMSKGE---------------------PKKYSLDPE 2267
+ +G NS C + + ++ + K DP
Sbjct: 85 NCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPA 144
Query: 2268 EIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG----KCTKCQCNGHADTC 2322
I GP D CV C+ GE+C+ C GY+ LDG CT+C C GH+ +C
Sbjct: 145 GI-----AGPC-DAGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASC 196
Score = 50.8 bits (120), Expect = 2e-05
Identities = 60/247 (24%), Positives = 83/247 (33%), Gaps = 59/247 (23%)
Query: 2141 TGYTMDNMTGL-CRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGA 2199
TGY +DN+T + RPV + C C G+ G+ C +C + A +G
Sbjct: 357 TGY-IDNVTLISARPVSG-----APAPWVEQCICPVGYKGQFCQ-DCASGYKRDSARLGP 409
Query: 2200 RDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRG---NSHICISRKELQMSK 2256
C+ C +C+ GGG C P C N I + +
Sbjct: 410 FGTCIPC-------NCQ-----------GGGACDPDTGDCYSGDENPDIECADCPIGFYN 451
Query: 2257 GEPKKYSLDPEEIENWVTEG--PSEDEAVCVNCQNNSYGEKCESCLQGYFLLD------- 2307
S P N + P +E VC NC G +CE C GYF
Sbjct: 452 DPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 2308 GKCTKCQCNGHAD-----TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRE 2362
C CQCN + D C+ G C +NT C +C+
Sbjct: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTA----------------GIYCDQCKA 555
Query: 2363 SFHGSPL 2369
+ G PL
Sbjct: 556 GYFGDPL 562
Score = 49.7 bits (117), Expect = 4e-05
Identities = 36/121 (29%), Positives = 48/121 (39%), Gaps = 18/121 (14%)
Query: 1104 CRKRGPGFCD-ECQDWTWGEH-----CERCRPGSFGNATGSRGCRPCQC-NGHG-----D 1151
C +G G CD + D G+ C C G + + R C+PC C NG +
Sbjct: 416 CNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPE 475
Query: 1152 PRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALG 1211
C+N C GA C+LC+ GY+GDP R C NV A G
Sbjct: 476 TEEVVCNN------CPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASG 529
Query: 1212 S 1212
+
Sbjct: 530 N 530
Score = 43.9 bits (102), Expect = 0.002
Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 46/178 (25%)
Query: 2215 CEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVT 2274
C C L + +A C C G S CI +EL G +
Sbjct: 8 CCLCFSLLLPAARATSRREVCD--CNGKSRQCIFDRELHRQTGNGFR------------- 52
Query: 2275 EGPSEDEAVCVNCQNNSYGEKCESCLQGYF--LLDGKCTKCQCNGHADTCNEQDGTG-CP 2331
C+NC +N+ G CE C G++ +C C CN D +G C
Sbjct: 53 ---------CLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCS 103
Query: 2332 CQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHG-SPLGGQQCYRLISVEQECCLDP 2388
C+ TG +C +C FH + G Q RL+ + +C DP
Sbjct: 104 CKPGV-TGA---------------RCDRCLPGFHMLTDAGCTQDQRLL--DSKCDCDP 143
Score = 42.4 bits (98), Expect = 0.006
Identities = 53/215 (24%), Positives = 77/215 (35%), Gaps = 44/215 (20%)
Query: 2060 CALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPED-ECANG 2118
C + + C CA G + R G P C G +C P+ +C +G
Sbjct: 384 CPVGYKGQFCQDCASGYKRDSARLGPFGTCIP-----CNCQGGG----ACDPDTGDCYSG 434
Query: 2119 HHDCNETQNCHDQPHGY-----------ECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVE 2167
D N C D P G+ C C G++ M VC C G V
Sbjct: 435 --DENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVC-NNCPPG--VT 489
Query: 2168 PDHCR-CHFGFVG---------RNCSTECRCNRHSECAGVGARDH----CLLCRNHTKGS 2213
C C G+ G R C C+CN + + + G D CL C ++T G
Sbjct: 490 GARCELCADGYFGDPFGEHGPVRPCQP-CQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
Query: 2214 HCEQCLPLFVGSAVG---GGTCRPCHAFCRGNSHI 2245
+C+QC + G + CR C+ G+ +
Sbjct: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPV 583
Score = 34.7 bits (78), Expect = 1.3
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 3/36 (8%)
Query: 143 PGGCQSHGQCQPPGVCACEPGWGGPDC--GLQECSA 176
P G + G C+ G C C+PG+GGP+C G C A
Sbjct: 577 PMGSEPVG-CRSDGTCVCKPGFGGPNCEHGAFSCPA 611
Score = 33.9 bits (76), Expect = 2.3
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 8/59 (13%)
Query: 1361 AGAGLCRCPQGWAG------PHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDC 1413
AG +C G+ G P + C NCN +S G C+C GFGGP+C
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRAC--NCNPMGSEPVGCRSDGTCVCKPGFGGPNC 602
Score = 32.7 bits (73), Expect = 5.1
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 6/46 (13%)
Query: 1144 CQCNGHGDP----RRGHCDNLSGL-CF-CQDHTEGAHCQLCSPGYY 1183
C CNG R H +G C C D+T+G HC+ C G+Y
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY 73
Score = 32.0 bits (71), Expect = 8.7
Identities = 29/127 (22%), Positives = 39/127 (30%), Gaps = 8/127 (6%)
Query: 1816 PEACNQSGACTWCHGACLSGDQAHRLGCG-------GSPCSPMPRSPEECRRLRTCSECL 1868
P C GAC G C SGD+ + C P P P C +CS
Sbjct: 415 PCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMP 474
Query: 1869 ARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQR-EVFWAGNCSEA 1927
+ RC+ C + G G +G C+ N + +GNC
Sbjct: 475 ETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRL 534
Query: 1928 ACGAADC 1934
C
Sbjct: 535 TGRCLKC 541
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 87.0 bits (214), Expect = 2e-16
Identities = 100/414 (24%), Positives = 154/414 (37%), Gaps = 79/414 (19%)
Query: 807 LRQGGAHCGDDGAGGSLLVLVPTLCPLCEEHRDCHACT-QDPFCEWHQSTSRKGDAACSR 865
L +GG +G+ L L P E+ D + C+ D C + + G CS
Sbjct: 1168 LCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSC 1227
Query: 866 RGRGRGALKSPEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRG 925
G A + C + + C +QC + ++ C Y C
Sbjct: 1228 NP-GYQATPDRQGCTDIDECMIMNGGC---DTQCTNSEGSYECSCSEGYALMPDGRSCAD 1283
Query: 926 WDD--------------SVHSEPRCRSCDGFLTCHE---CLQSHECGWCGNEDNPTLGRC 968
D+ ++ E RC DGF+ + C+ +EC N C
Sbjct: 1284 IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNI-------C 1336
Query: 969 LQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTP 1028
+ G+ G C +G + + C DVDEC +G C A+CLN P
Sbjct: 1337 MFGECENTKGSFICHCQLGYSV--------KKGTTGCTDVDECEIGAHNCDMHASCLNIP 1388
Query: 1029 LSYECHCQRGYQGDGISHCNRTCLEDCGHGV--CS-------GPPDFTCVCDLGWTSDLP 1079
S++C C+ G+ G+GI + L++C +G CS P + C C G+T D
Sbjct: 1389 GSFKCSCREGWIGNGIKCID---LDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGD-- 1443
Query: 1080 PPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSR 1139
CS C+ + + + G +C + CE C G F A+ SR
Sbjct: 1444 ---------GFTCSDVDECAENINLCENG-----QCLNVPGAYRCE-CEMG-FTPASDSR 1487
Query: 1140 GCRPC-QCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSC 1192
C+ +C+ G C+NL G+ C +C GY D R GG+C
Sbjct: 1488 SCQDIDECSFQNICVFGTCNNLPGMFHC----------ICDDGYELD-RTGGNC 1530
Score = 68.9 bits (167), Expect = 6e-11
Identities = 133/631 (21%), Positives = 208/631 (32%), Gaps = 115/631 (18%)
Query: 1812 LLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLRTCSECLARH 1871
L S E C C+ C +G + +G C+P ++ + + EC+ +
Sbjct: 1191 LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMN 1250
Query: 1872 PRTLQPGDGEASTPRCKWCTNCPEGACIGRNG-SCTSENDCRINQREVFWAGNCSEAACG 1930
D + + + +C EG + +G SC ++C N C
Sbjct: 1251 GGC----DTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPD-----------ICD 1295
Query: 1931 AADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPC 1990
C E +C+ F + + + + V + S+ + + S C
Sbjct: 1296 GGQCTNIPGEYRCLCYDGFMASMDMKTCIDVN---ECDLNSNICMFGECENTKGSFICHC 1352
Query: 1991 PTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS-PSYLPLRCMAGGCGRLLR--GP 2047
+ T C D + G +C +S CL+ P C G G ++
Sbjct: 1353 QLGYSVKKGTTGCTDVDECEIGAHNCDMHAS---CLNIPGSFKCSCREGWIGNGIKCIDL 1409
Query: 2048 ESCSLGCAQATQCALCLRRPHCGWCAWG-GQDGGG-------RCMEGGLSGPRDGLTCGR 2099
+ CS G Q + A C+ P CA G G G C E ++ +G
Sbjct: 1410 DECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAEN-INLCENGQCLNV 1468
Query: 2100 PGA-----SWAFL------SCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNM 2148
PGA F SC DEC+ + C++ P + C C GY +D
Sbjct: 1469 PGAYRCECEMGFTPASDSRSCQDIDECS--FQNICVFGTCNNLPGMFHCICDDGYELDRT 1526
Query: 2149 TGLCRPV--CAQ--GCVNGSCVEPD---HCRCHFGFVGRNCSTECRCNRHSEC------- 2194
G C + CA CVNG CV C C F C NR C
Sbjct: 1527 GGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPR 1586
Query: 2195 ----------AGVG-ARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNS 2243
GVG +R C G+ CE C P+ + C G
Sbjct: 1587 GDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPV---------NSTEYYTLCPGGE 1637
Query: 2244 HICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCV--NCQNNSYGEKCESCLQ 2301
P ++ E+I+ E +C NC N +CE C Q
Sbjct: 1638 GF------------RPNPITIILEDIDEC-----QELPGLCQGGNCINTFGSFQCE-CPQ 1679
Query: 2302 GYFLLDGK--CTKC-QCNGHADTCNEQDGTGCPCQNNTETGTC----QGSSPSDRRDCYK 2354
GY+L + C +C H C G G C N TC + + +C
Sbjct: 1680 GYYLSEDTRICEDIDECFAHPGVC----GPG-TCYNTLGNYTCICPPEYMQVNGGHNCMD 1734
Query: 2355 YQCAKCRESFHGSPLGGQQCYRLISVEQECC 2385
+ + C S++G+ + + + ++ CC
Sbjct: 1735 MRKSFCYRSYNGTTCENELPFNV--TKRMCC 1763
Score = 62.8 bits (151), Expect = 5e-09
Identities = 73/306 (23%), Positives = 110/306 (35%), Gaps = 51/306 (16%)
Query: 2107 LSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLC--RPVCAQ---GCV 2161
L C DEC+NG + C +C + P Y C C G+ + + G C R C + C
Sbjct: 1846 LVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKL-SPNGACVDRNECLEIPNVCS 1904
Query: 2162 NGSCVEPD---HCRCHFGFVGRNCSTEC----RCNRH----SECAGVGARDHCLLCRNHT 2210
+G CV+ C CH GF T C C RH C +C LC
Sbjct: 1905 HGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNC-LCYPGF 1963
Query: 2211 KGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEE-- 2268
+ +H CL + S+ G CR F S C+ + +++ K +D E
Sbjct: 1964 ELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELT--PDGKNCIDTNECV 2021
Query: 2269 -IENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKC-QCNGHADTC---- 2322
+ + G CQN +C C GY + C +C+ + C
Sbjct: 2022 ALPGSCSPG---------TCQNLEGSFRC-ICPPGYEVKSENCIDINECDEDPNICLFGS 2071
Query: 2323 --NEQDGTGCPCQNNTETGTCQGSSPSDR-RDCYKYQCAKCRESFHGSPLGGQQCYRLIS 2379
N G C C G SD R C+ + + C +F + + +
Sbjct: 2072 CTNTPGGFQCLCP--------PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFN--T 2121
Query: 2380 VEQECC 2385
+ +CC
Sbjct: 2122 TKAKCC 2127
Score = 58.9 bits (141), Expect = 7e-08
Identities = 67/271 (24%), Positives = 91/271 (33%), Gaps = 77/271 (28%)
Query: 1979 PMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSY------LP 2032
P P PP P P P + + G++GG+ L+P Y +
Sbjct: 30 PQPPPPKPPRPQPPPQQVRSA------TAGSEGGF------------LAPEYREEGAAVA 71
Query: 2033 LRCMAGGCGRLLRGPESC-----SLGCAQ------ATQCALCLRRPHCG--WCAWGGQDG 2079
R G +LRGP C S C QC + + R CG +C+ +
Sbjct: 72 SRVRRRGQQDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCS---RPN 128
Query: 2080 GGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSC 2139
C G +S TCG + C CA+ H C C
Sbjct: 129 MCTCSSGQISS-----TCGSKSIQQCSVRCMNGGTCADDH-----------------CQC 166
Query: 2140 KTGYTMDNMTGLCRPVCAQGCVNGS-CVEPDHCRCHFGFVGRNCSTECRCN------RHS 2192
+ GY T +PVC GC NG C+ P+ C C +GF G C + R +
Sbjct: 167 QKGYIG---TYCGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQ 223
Query: 2193 ECAG-----VGARDHCLLCRNHTKGSHCEQC 2218
C G V + C G CE C
Sbjct: 224 MCQGQLTGIVCTKTLCCATIGRAWGHPCEMC 254
Score = 58.2 bits (139), Expect = 1e-07
Identities = 58/212 (27%), Positives = 76/212 (35%), Gaps = 46/212 (21%)
Query: 1005 CPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC--NRTCLE---DCGHGV 1059
C D+DEC G C A C+N+P SY C C G++ C CLE C HG+
Sbjct: 1848 CEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGL 1907
Query: 1060 CSG-PPDFTCVCDLGWTSDLPPPTPAPGPPAPR-------CSRDCGCSFHSHCRKRGPGF 1111
C + C+C G+ + R C G S++ C PGF
Sbjct: 1908 CVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVG-SYNCLCY---PGF 1963
Query: 1112 ----------CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCN--------GHGDPR 1153
DEC + +G+ C G G C CN G
Sbjct: 1964 ELTHNNDCLDIDECSSF-FGQVCRN------GRCFNEIGSFKCLCNEGYELTPDGKNCID 2016
Query: 1154 RGHCDNLSGLC---FCQDHTEGAHCQLCSPGY 1182
C L G C CQ + EG+ +C PGY
Sbjct: 2017 TNECVALPGSCSPGTCQ-NLEGSFRCICPPGY 2047
Score = 54.3 bits (129), Expect = 2e-06
Identities = 97/443 (21%), Positives = 137/443 (30%), Gaps = 99/443 (22%)
Query: 789 GCLADQGC---------GWCLT---SATCHLRQG------GAHCGDDGAGGSLLVLVPTL 830
GC+ + C G C+ S C +G G C D+ G ++ T+
Sbjct: 2335 GCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTI 2394
Query: 831 CPLCEEHRDC---HACTQDPFCEW-HQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQR 886
C + R+ C D W HQ C G + P P +
Sbjct: 2395 CQMASSSRNLVTKSECCCDGGRGWGHQCE------LCPLPGTAQYKKICPHG-PGYTTDG 2447
Query: 887 LTCEDC-----LANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDG 941
++C L + QC + CF Y C D+ S C
Sbjct: 2448 RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCN---- 2503
Query: 942 FLTCHECLQSHEC----GWCGNEDNPT---LGRCLQGDFS------GPLGGGNCSLWVGE 988
C S++C G+ ED T L C + LGG C G
Sbjct: 2504 -YICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPG- 2561
Query: 989 GLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDG----- 1043
+ C D +EC + C + C NTP S+ C CQRG+ D
Sbjct: 2562 ---------FTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC 2612
Query: 1044 --ISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFH 1101
+ C+ C HG + + C C G+ +C + CS
Sbjct: 2613 EDVDECDGN--HRCQHGCQNILGGYRCGCPQGYIQHY---------QWNQCVDENECSNP 2661
Query: 1102 SHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC-QCNGHGDPRRGHCDNL 1160
+ C G C T G + C P F S C +C+ +P C N
Sbjct: 2662 NAC---GSASCYN----TLGSYKCAC-PSGFSFDQFSSACHDVNECSSSKNPCNYGCSN- 2712
Query: 1161 SGLCFCQDHTEGAHCQLCSPGYY 1183
TEG + C PGYY
Sbjct: 2713 ---------TEGGYLCGCPPGYY 2726
Score = 53.5 bits (127), Expect = 3e-06
Identities = 64/244 (26%), Positives = 84/244 (34%), Gaps = 47/244 (19%)
Query: 959 NEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARC 1018
NE G C G +G C G L + C D+DECR+ C
Sbjct: 1075 NECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEER--------NCTDIDECRISPDLC 1126
Query: 1019 HPRATCLNTPLSYECHCQRGYQGD--------GISHCNRTCLEDCGHGVC-SGPPDFTCV 1069
C+NTP S+EC C GY+ I C R L C G C + F C
Sbjct: 1127 GS-GICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLL-CRGGTCVNTEGSFQCD 1184
Query: 1070 CDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRP 1129
C LG P C CS + + G +C + C C P
Sbjct: 1185 CPLGHEL---------SPSREDCVDINECSLSDNLCRNG-----KCVNMIGTYQCS-CNP 1229
Query: 1130 GSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQ-DHTEGAHCQLCSPGYYGDPRA 1188
G + +GC C ++G C Q ++EG++ CS GY P
Sbjct: 1230 G-YQATPDRQGCTDID----------ECMIMNGGCDTQCTNSEGSYECSCSEGYALMP-D 1277
Query: 1189 GGSC 1192
G SC
Sbjct: 1278 GRSC 1281
Score = 50.8 bits (120), Expect = 2e-05
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCG---LQECSAYCGSHGTCASPLGPCRCEPGF 197
+C C G C P +C C G CG +Q+CS C + GTCA C+C+ G+
Sbjct: 114 ICRNSC-GDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCAD--DHCQCQKGY 170
Query: 198 LGRACDLHLWEN 209
+G C + EN
Sbjct: 171 IGTYCGQPVCEN 182
Score = 50.4 bits (119), Expect = 2e-05
Identities = 107/461 (23%), Positives = 148/461 (32%), Gaps = 107/461 (23%)
Query: 767 EISFFFLEPYRSSSCTSYSSCLGCLADQGCGW------CLTSATCHLRQGGAHCGD-DGA 819
E S FF + R+ C + CL ++G C+ + C G G
Sbjct: 1976 ECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNL 2035
Query: 820 GGSLLVLVPTLCPLCEEHR-DCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPE 877
GS + P + E+ D + C +DP C + T+ G C
Sbjct: 2036 EGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCL------------- 2082
Query: 878 ECPP---LCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGC-----RGW--- 926
CPP L C D S C C + A+ C GW
Sbjct: 2083 -CPPGFVLSDNGRRCFD--TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDP 2139
Query: 927 ------DDSVHSEPRCRSCDGFLTC--------HECLQSHECGWCGNEDNPTLGRCLQGD 972
DD V + C G + +ECL+S G C N G+C+ D
Sbjct: 2140 CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESP--GICSN------GQCINTD 2191
Query: 973 FSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHP--RATCLNTPLS 1030
G C +G L + RC D DEC +G +P TC N S
Sbjct: 2192 -----GSFRCECPMGYNLD--------YTGVRCVDTDECSIG----NPCGNGTCTNVIGS 2234
Query: 1031 YECHCQRGYQGDGISHCN--RTCLED---CGHGVCSGPPDFTCVCDLGWT--------SD 1077
+EC+C G++ + +C C ++ C + + C C +G+ D
Sbjct: 2235 FECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKD 2294
Query: 1078 LPPPTPAPGPPAPR---CSR-----DCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRP 1129
L R C C C R G G DE + T CE
Sbjct: 2295 LDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECRTKPGICEN--- 2351
Query: 1130 GSFGNATGSRGCRPCQCN-GHGDPRRG-HC-DNLSGLCFCQ 1167
G G C+CN G G C DN GLCF +
Sbjct: 2352 ---GRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAE 2389
Score = 48.1 bits (113), Expect = 1e-04
Identities = 99/437 (22%), Positives = 131/437 (29%), Gaps = 100/437 (22%)
Query: 833 LCEEHRDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP-LC-----SQR 886
LC+ + DC CE + AC R L+ P C LC S +
Sbjct: 1860 LCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNE---CLEIPNVCSHGLCVDLQGSYQ 1916
Query: 887 LTCEDCLANSSQCAWCQSTHTCFLFAAYLARYP--HGGCRGWDDSVHSEPRCRSCDGFLT 944
C + S C C R+P +G C+ S + C GF
Sbjct: 1917 CICHNGFKASQDQTMCMDVDEC-------ERHPCGNGTCKNTVGSYN----CLCYPGFEL 1965
Query: 945 CH--ECLQSHEC----------GWCGNEDNPTLGRCLQGDFSGPLGG------------G 980
H +CL EC G C NE C +G P G G
Sbjct: 1966 THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPG 2025
Query: 981 NCSLWVGEGLGLPVALPARWAYA----RCPDVDECRLGLARCHPRATCLNTPLSYECHCQ 1036
+CS + L Y C D++EC C +C NTP ++C C
Sbjct: 2026 SCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICL-FGSCTNTPGGFQCLCP 2084
Query: 1037 RGY-QGDGISHCNRT----CLEDCGHGVCSGPPDFT-----CVCDLGWTSDLPPPTPAPG 1086
G+ D C T C + +G CS P F C C P G
Sbjct: 2085 PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCS-------KMPGEGWG 2137
Query: 1087 PPAPRCSRDCGCSFHSHCR-------------------KRGPGFCD--ECQDWTWGEHCE 1125
P C +D +F C PG C +C + CE
Sbjct: 2138 DPCELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCE 2197
Query: 1126 RCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGD 1185
C G + TG R +C+ G C N+ G C C+ G+
Sbjct: 2198 -CPMGYNLDYTGVRCVDTDECSIGNPCGNGTCTNVIGSFECN----------CNEGFEPG 2246
Query: 1186 PRAGGSCFRECGGRALL 1202
P EC LL
Sbjct: 2247 PMMNCEDINECAQNPLL 2263
Score = 47.0 bits (110), Expect = 3e-04
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 2128 CHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTEC- 2186
C + H Y C T+ P+C C +G C P+ C C G + C ++
Sbjct: 89 CGSRFHSY--CCPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGSKSI 146
Query: 2187 -RCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTC 2232
+C+ G A DHC C+ G++C Q P+ GG C
Sbjct: 147 QQCSVRCMNGGTCADDHC-QCQKGYIGTYCGQ--PVCENGCQNGGRC 190
Score = 45.8 bits (107), Expect = 6e-04
Identities = 84/348 (24%), Positives = 115/348 (33%), Gaps = 84/348 (24%)
Query: 865 RRGRGRGALKSPEECPPLCSQRLTCEDCLANS-SQCA-------WCQSTHTCFLFAAYLA 916
R G G P C CS C + S QC+ C H C Y+
Sbjct: 116 RNSCGDGFCSRPNMCT--CSSGQISSTCGSKSIQQCSVRCMNGGTCADDH-CQCQKGYIG 172
Query: 917 RYP-----HGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQG 971
Y GC+ + RC GF T +C + + G C + N + QG
Sbjct: 173 TYCGQPVCENGCQNGGRCIGPN-RCACVYGF-TGPQCERDYRTGPCFTQVN---NQMCQG 227
Query: 972 DFSGPLGGGN-CSLWVGEGLGLPVAL------PARWAY------ARCPDVDECRLGLARC 1018
+G + C +G G P + P R + C DVDEC+ C
Sbjct: 228 QLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC 287
Query: 1019 HPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLED----------CGHGVCSGP-PDFT 1067
C+NT S+EC C G++ S + C ED C G CS +
Sbjct: 288 QG-GNCINTVGSFECRCPAGHKQ---SETTQKC-EDIDECSIIPGICETGECSNTVGSYF 342
Query: 1068 CVCDLGWTSDLPPPTPAPGPPAPRC-SRDCGCSF----HSHCRKRGPG-------FCDEC 1115
CVC G+ + RC + G F + C + PG C+
Sbjct: 343 CVCPRGYVT---------STDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Query: 1116 QDWTWG------------EHCERCRPG-SFGNATGSRGCRPCQCNGHG 1150
+ W G E+ C G G GS G RP G+G
Sbjct: 394 RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNG 441
Score = 45.4 bits (106), Expect = 8e-04
Identities = 72/306 (23%), Positives = 109/306 (35%), Gaps = 44/306 (14%)
Query: 2108 SCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV--CAQG--CVNG 2163
+C DEC + N C ++ ++C CK G+ + C V C C+NG
Sbjct: 614 NCVDHDECTTTNMCLNGM--CINEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNG 671
Query: 2164 SCVEPD---HCRCHFGF-VGRNCSTECRCNRHSECAGVGARDHCL--LCRNHTKGSHCEQ 2217
C+ + C C G VG + + S C G + C+ TK C
Sbjct: 672 HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECC-- 729
Query: 2218 CLPLFVGSAVGGGTCRPCHAFCRGNSH-ICISRKELQMSKGEPKKYSLDPEEIENWVTEG 2276
C G G C+PC A H +C S + + + + +LDP+ N + E
Sbjct: 730 CANPDYGF---GEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICEN 786
Query: 2277 PSEDEAVCVNC--QNNSYGEKC---ESCLQGYFLLDGKCTKCQCNGHADTCNEQDGT-GC 2330
N + ++ G C + CL L D NG C G+ C
Sbjct: 787 LRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD--------NG---LCRNTPGSYSC 835
Query: 2331 PCQN----NTETGTCQGSSPSDRRDCYKYQCAKCRESFH-----GSPLGGQQCYRLISVE 2381
C TET TC+ + + C C SF+ GS L + S++
Sbjct: 836 TCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
Query: 2382 QECCLD 2387
C L+
Sbjct: 896 GTCWLN 901
Score = 45.1 bits (105), Expect = 0.001
Identities = 94/408 (23%), Positives = 136/408 (33%), Gaps = 91/408 (22%)
Query: 838 RDCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLANS 896
RD + C DP C + +G C+ G S C + ++CL N
Sbjct: 767 RDINECALDPDICANGICENLRGSYRCNCNS-GYEPDASGRNC-------IDIDECLVNR 818
Query: 897 SQC--AWCQST---HTCFLFAAYLARYPHGGCRGWDDSVHSEP----RCRSCDGFLTCHE 947
C C++T ++C Y+ R C ++ S P CR+ G C E
Sbjct: 819 LLCDNGLCRNTPGSYSCTCPPGYVFRTETETCEDINEC-ESNPCVNGACRNNLGSFNC-E 876
Query: 948 CLQSHECG--------------WCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLP 993
C + W +D+ RC + + +G C +G G P
Sbjct: 877 CSPGSKLSSTGLICIDSLKGTCWLNIQDS----RC-EVNINGATLKSECCATLGAAWGSP 931
Query: 994 -------VALP---ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDG 1043
A P AR C DV+EC + C P C+N+ S+ C C G DG
Sbjct: 932 CERCELDTACPRGLARIKGVTCEDVNECEVFPGVC-PNGRCVNSKGSFHCECPEGLTLDG 990
Query: 1044 ISHCNRTCL-------------EDCGHGVCSGPPDFTCVCDLG--WTSDLPP-PTPAPGP 1087
R CL ++C H V C C +G W ++ P P
Sbjct: 991 ---TGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKE 1047
Query: 1088 PAPRCSRDCGCSFHSHCRKRGPGFCD--ECQDWTWGEHCERCRPGSFGNATGSRGCRPCQ 1145
C R G + P + D EC+ + C G N GS CR C
Sbjct: 1048 YETLCPRGAGFANRGDVLTGRPFYKDINECKAFP-----GMCTYGKCRNTIGSFKCR-CN 1101
Query: 1146 CNGHGDPRRGHCDNL-----------SGLCFCQDHTEGAHCQLCSPGY 1182
D +C ++ SG+C +T G+ C GY
Sbjct: 1102 SGFALDMEERNCTDIDECRISPDLCGSGICV---NTPGSFECECFEGY 1146
Score = 44.7 bits (104), Expect = 0.001
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 51/231 (22%)
Query: 1005 CPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC---NRTCLED---CGHG 1058
C DVDEC C+NTP SY C C G+Q C+++ C +G
Sbjct: 533 CIDVDECTSNPCT---NGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNG 589
Query: 1059 VC-SGPPDFTCVCDLGW--TSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDEC 1115
C + F C+C+ G+ T+D C H C C
Sbjct: 590 RCVNTDGSFQCICNAGFELTTD-----------------GKNCVDHDECTTTNMCLNGMC 632
Query: 1116 QDWTWGEHCERCRPGSFGNATGSRGCRPC-QCNGHGDPRRGHCDNLSGLCFCQDHTEGAH 1174
+ C C+PG F A R C +C G GHC N G C
Sbjct: 633 INEDGSFKC-ICKPG-FVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCD------- 683
Query: 1175 CQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGA 1225
C PG A G R C + T++ S G + G + P GA
Sbjct: 684 ---CPPGL-----AVGMDGRVC----VDTHMRSTCYGGIKKGVCVRPFPGA 722
Score = 44.7 bits (104), Expect = 0.001
Identities = 53/233 (22%), Positives = 81/233 (34%), Gaps = 43/233 (18%)
Query: 2094 GLTCG-RPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGL- 2151
G TC PG + +C +EC + C C + P + C C+ G+++D TGL
Sbjct: 2553 GFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLD-ATGLN 2611
Query: 2152 CRPV--------CAQGCVNGSCVEPDHCRCHFGFV----GRNCSTECRCNRHSEC----- 2194
C V C GC N + C C G++ C E C+ + C
Sbjct: 2612 CEDVDECDGNHRCQHGCQN--ILGGYRCGCPQGYIQHYQWNQCVDENECSNPNACGSASC 2669
Query: 2195 ------------AGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGN 2242
+G C + + S + + GG C + R
Sbjct: 2670 YNTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNTEGGYLCGCPPGYYRVG 2729
Query: 2243 SHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEK 2295
C+S + +KG+ SLD E V E + C C+ N Y +K
Sbjct: 2730 QGHCVS--GMGFNKGQ--YLSLDTE-----VDEENALSPEACYECKINGYSKK 2773
Score = 44.3 bits (103), Expect = 0.002
Identities = 64/246 (26%), Positives = 80/246 (32%), Gaps = 65/246 (26%)
Query: 2109 CPPEDECANGHHDCNET-QNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCV------ 2161
C DECA G HDC C + + C C G + R +GCV
Sbjct: 2292 CKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG--------MARRPDGEGCVDENECR 2343
Query: 2162 -------NGSCVE---PDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLC---RN 2208
NG CV C C+ GF + TEC NR C + C + RN
Sbjct: 2344 TKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMASSSRN 2403
Query: 2209 HTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEE 2268
S C GG RG H C EL G + + P
Sbjct: 2404 LVTKSEC----------CCDGG---------RGWGHQC----ELCPLPGTAQYKKICPHG 2440
Query: 2269 IENWVTEGPSEDEA-----VCVN--CQNNSYGEKCESCLQGYFLLDGKCTKC----QCNG 2317
+ T+G DE +C N C N +C C GY D T C +C+
Sbjct: 2441 -PGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRC-FCKVGY-TTDISGTSCIDLDECSQ 2497
Query: 2318 HADTCN 2323
CN
Sbjct: 2498 SPKPCN 2503
Score = 44.3 bits (103), Expect = 0.002
Identities = 68/261 (26%), Positives = 96/261 (36%), Gaps = 47/261 (18%)
Query: 2108 SCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV---------CAQ 2158
SC DEC+ CN C + Y+CSC GY + C+ + C
Sbjct: 2488 SCIDLDECSQSPKPCNYI--CKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQHNCQF 2545
Query: 2159 GCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAG----VGARDHCLLCRNHTKGSH 2214
CVN + C+C GF + + C ++EC GA+ C +T GS
Sbjct: 2546 LCVN--TLGGFTCKCPPGFTQHHTA----CIDNNECGSQPSLCGAKGIC----QNTPGSF 2595
Query: 2215 CEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSK---GEPKKYSLDPEEIEN 2271
+C F A G C C GN H C + + G P+ Y + +
Sbjct: 2596 SCECQRGFSLDAT-GLNCEDVDE-CDGN-HRCQHGCQNILGGYRCGCPQGY-IQHYQWNQ 2651
Query: 2272 WVTEGPSEDEAVC--VNCQNNSYGEKCESCLQGYFLLDGKCTKC----QCNGHADTCNEQ 2325
V E + C +C N KC +C G F D + C +C+ + CN
Sbjct: 2652 CVDENECSNPNACGSASCYNTLGSYKC-ACPSG-FSFDQFSSACHDVNECSSSKNPCN-- 2707
Query: 2326 DGTGCPCQNNTETGTCQGSSP 2346
GC +NTE G G P
Sbjct: 2708 --YGC---SNTEGGYLCGCPP 2723
Score = 42.4 bits (98), Expect = 0.006
Identities = 113/485 (23%), Positives = 156/485 (32%), Gaps = 132/485 (27%)
Query: 1005 CPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQ-----------------------G 1041
C D+DEC + C C+NTP YEC+C +Q G
Sbjct: 1530 CTDIDECADPI-NC-VNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRG 1587
Query: 1042 DGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFH 1101
DG CN + G GV +C C LG A G P C ++
Sbjct: 1588 DGSLSCN----TEIGVGVSRS----SCCCSLG---------KAWGNPCETCPPVNSTEYY 1630
Query: 1102 SHCRKRGPGF-----------CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHG 1150
+ C G GF DECQ E C+ G+ N GS C C +
Sbjct: 1631 TLC-PGGEGFRPNPITIILEDIDECQ-----ELPGLCQGGNCINTFGSFQCE-CPQGYYL 1683
Query: 1151 DPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVAL 1210
C+++ CF AH +C PG + +C C + N +
Sbjct: 1684 SEDTRICEDIDE-CF-------AHPGVCGPGTCYNTLGNYTCI--CPPEYMQVNGGHNCM 1733
Query: 1211 GSRR------VGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPD 1264
R+ G + C + V +PC P CP
Sbjct: 1734 DMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWN-KPCEP---CP--------- 1780
Query: 1265 SSTPCTLSYVLAFDGFPRF---LDTG--VVQSDRSLIAAFC---------GQRRDRPLTV 1310
TP T + P F + TG V + I C G R T
Sbjct: 1781 --TPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTG 1838
Query: 1311 QALSGLLVLHWE----ANGSSSWGFNA----SVGSARCGSGG------PGSCPVPQECVP 1356
+ + LL++ + +NG + NA S GS RC G+C EC+
Sbjct: 1839 FSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLE 1898
Query: 1357 QDGAAGAGL---------CRCPQGW-AGPHCRMALCPENCNAH-TGAGTCNQSLGV--CI 1403
GL C C G+ A M + + C H G GTC ++G C+
Sbjct: 1899 IPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCL 1958
Query: 1404 CAEGF 1408
C GF
Sbjct: 1959 CYPGF 1963
Score = 41.2 bits (95), Expect = 0.014
Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 1337 SARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCN 1396
S+ CGS C V C+ G C+C +G+ G +C +C C G C
Sbjct: 138 SSTCGSKSIQQCSV--RCM-NGGTCADDHCQCQKGYIGTYCGQPVCENGCQ---NGGRCI 191
Query: 1397 QSLGVCICAEGFGGPDC 1413
C C GF GP C
Sbjct: 192 GP-NRCACVYGFTGPQC 207
Score = 41.2 bits (95), Expect = 0.014
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 142 CPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRA 201
C C + G C C C+ G+ G CG C C + G C P C C GF G
Sbjct: 149 CSVRCMNGGTCADDH-CQCQKGYIGTYCGQPVCENGCQNGGRCIGP-NRCACVYGFTGPQ 206
Query: 202 CD 203
C+
Sbjct: 207 CE 208
Score = 41.2 bits (95), Expect = 0.014
Identities = 36/115 (31%), Positives = 45/115 (39%), Gaps = 28/115 (24%)
Query: 2115 CANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV---CAQGCVNGSCVEPD-- 2169
C NG C Y C C GY D G C V + C NG CV
Sbjct: 505 CLNGR--------CIPTVSSYRCECNMGYKQD-ANGDCIDVDECTSNPCTNGDCVNTPGS 555
Query: 2170 -HCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRN----HTKGSHCEQCL 2219
+C+CH GF + T+ C EC G +LC+N +T GS QC+
Sbjct: 556 YYCKCHAGF--QRTPTKQACIDIDECIQNG-----VLCKNGRCVNTDGSF--QCI 601
Score = 39.3 bits (90), Expect = 0.055
Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 7/77 (9%)
Query: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGR 200
+C GCQ+ G+C P CAC G+ GP C + G C + + C+ G
Sbjct: 179 VCENGCQNGGRCIGPNRCACVYGFTGPQCERDYRT------GPCFTQVNNQMCQGQLTGI 232
Query: 201 ACDLHL-WENQGAGWWH 216
C L G W H
Sbjct: 233 VCTKTLCCATIGRAWGH 249
Score = 38.1 bits (87), Expect = 0.12
Identities = 49/200 (24%), Positives = 62/200 (31%), Gaps = 35/200 (17%)
Query: 2047 PESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGA---S 2103
P+ C G + C C Q G C G C P S
Sbjct: 258 PQPCRRGFIPNIRTGACQDVDEC-------QAIPGICQGGNCINTVGSFECRCPAGHKQS 310
Query: 2104 WAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYT--------MDNMTGLCRPV 2155
C DEC+ C ET C + Y C C GY +D TG+
Sbjct: 311 ETTQKCEDIDECSIIPGIC-ETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGM---- 365
Query: 2156 CAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGA-RDHCLLCRNHTKGSH 2214
C G VNG C + GR +C C C G+G + C + +
Sbjct: 366 CFSGLVNGRCAQE--------LPGRMTKMQC-CCEPGRCWGIGTIPEACPVRGSEEYRRL 416
Query: 2215 CEQCLPLFVGSAVGGGTCRP 2234
C LP+ G G RP
Sbjct: 417 CMDGLPM--GGIPGSAGSRP 434
Score = 37.7 bits (86), Expect = 0.16
Identities = 132/640 (20%), Positives = 202/640 (31%), Gaps = 144/640 (22%)
Query: 1811 RLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLRTCSECLAR 1870
R + + C G C +G C++ + + R C P + C S C
Sbjct: 654 RYCTDVDECQTPGICM--NGHCINSEGSFRCDC--PPGLAVGMDGRVCVDTHMRSTCYGG 709
Query: 1871 HPR--TLQPGDGEASTPRC----------KWCTNCPEGACIGRNGSCTSENDCRINQREV 1918
+ ++P G + C + C CP +G C+S ++ R++
Sbjct: 710 IKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDI 769
Query: 1919 FWAGNCS--EAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLN 1976
C+ C CE +C ++ R + + C + LL
Sbjct: 770 ---NECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDE-----CLVNRLLC 821
Query: 1977 VSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLR-C 2035
+ + C P SC G V+ + + C + C
Sbjct: 822 DNGL-------------CRNTPGSYSCTCPPGY-------VFRTETETCEDINECESNPC 861
Query: 2036 MAGGCGRLLRGPE-SCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDG 2094
+ G C L CS G ++ +C+ G C QD RC
Sbjct: 862 VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLK-GTCWLNIQDS--RCEVNINGATLKS 918
Query: 2095 LTCGRPGASWAFLS--CPPEDECANGH--------HDCNETQ---------NCHDQPHGY 2135
C GA+W C + C G D NE + C + +
Sbjct: 919 ECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSKGSF 978
Query: 2136 ECSCKTGYTMDNMTGLCRPVCAQGCV----NGSCVEP-------DHCRCHFGFVGRNCST 2184
C C G T+D +C + + C C+ P D C C VG T
Sbjct: 979 HCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCC---AVGAAWGT 1035
Query: 2185 ECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGG--TCRP-------C 2235
EC EC G +++ LC P G A G T RP C
Sbjct: 1036 EC-----EECPKPGTKEYETLC-------------PRGAGFANRGDVLTGRPFYKDINEC 1077
Query: 2236 HAF----CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVN--CQN 2289
AF G I + + + G ++LD EE + +C + C N
Sbjct: 1078 KAFPGMCTYGKCRNTIGSFKCRCNSG----FALDMEERNCTDIDECRISPDLCGSGICVN 1133
Query: 2290 NSYGEKCESCLQGY---FLLDGKC---TKCQCNG---HADTCNEQDGT-GCPCQNNTETG 2339
+CE C +GY F++ C +C+ N TC +G+ C C E
Sbjct: 1134 TPGSFECE-CFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHEL- 1191
Query: 2340 TCQGSSPSDRRDCYKY-QCA----KCRESFHGSPLGGQQC 2374
SPS R DC +C+ CR + +G QC
Sbjct: 1192 -----SPS-REDCVDINECSLSDNLCRNGKCVNMIGTYQC 1225
Score = 37.0 bits (84), Expect = 0.27
Identities = 36/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 939 CDGFLTC-HEC---LQSHECGWC--GNEDNPTLGRCL-QGDFSGPLGGGNCSLWVGEGLG 991
CDG C H C L + CG C G + +C+ + + S P G+ S + G
Sbjct: 2618 CDGNHRCQHGCQNILGGYRCG-CPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLG-S 2675
Query: 992 LPVALPARWAY----ARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC 1047
A P+ +++ + C DV+EC C+ C NT Y C C GY G HC
Sbjct: 2676 YKCACPSGFSFDQFSSACHDVNECSSSKNPCN--YGCSNTEGGYLCGCPPGYYRVGQGHC 2733
Score = 36.6 bits (83), Expect = 0.35
Identities = 49/217 (22%), Positives = 72/217 (33%), Gaps = 41/217 (18%)
Query: 1007 DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQ-GDGISHCNRTCLEDCGHG--VC--- 1060
D+DEC+ C C+N S+ C C G+ D + C +++C +G +C
Sbjct: 1808 DIDECKEIPGIC-ANGVCINQIGSFRCECPTGFSYNDLLLVCED--IDECSNGDNLCQRN 1864
Query: 1061 ----SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDE-- 1114
+ P + C C G+ + S + C + C + P C
Sbjct: 1865 ADCINSPGSYRCECAAGF----------------KLSPNGACVDRNECLEI-PNVCSHGL 1907
Query: 1115 CQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGL--CFCQDHTEG 1172
C D C C G + + +C H G C N G C C E
Sbjct: 1908 CVDLQGSYQC-ICHNGFKASQDQTMCMDVDECERH-PCGNGTCKNTVGSYNCLCYPGFEL 1965
Query: 1173 AHCQLC-----SPGYYGDPRAGGSCFRECGGRALLTN 1204
H C ++G G CF E G L N
Sbjct: 1966 THNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCN 2002
Score = 32.3 bits (72), Expect = 6.7
Identities = 66/305 (21%), Positives = 96/305 (31%), Gaps = 62/305 (20%)
Query: 2113 DECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCR 2172
DEC C + NC + ++C C GY + T +C + D C
Sbjct: 1652 DECQELPGLC-QGGNCINTFGSFQCECPQGYYLSEDTRICEDI-------------DECF 1697
Query: 2173 CHFGFVG----RNCSTECRCNRHSECAGVGARDHCL-----LCRNHTKGSHCEQCLPLFV 2223
H G G N C E V +C+ C G+ CE LP V
Sbjct: 1698 AHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNV 1757
Query: 2224 GSA-------VGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEG 2276
VG +PC + + + G ++ D + +
Sbjct: 1758 TKRMCCCTYNVGKAWNKPCEPCPTPGT------ADFKTICGNIPGFTFDIHTGKAVDIDE 1811
Query: 2277 PSEDEAVCVN--CQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQN 2334
E +C N C N +CE C G F + C+ D C+ D CQ
Sbjct: 1812 CKEIPGICANGVCINQIGSFRCE-CPTG-FSYNDLLLVCE---DIDECSNGDNL---CQR 1863
Query: 2335 NTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGG----QQCYRLISV-EQECCLDPT 2389
N + GS Y+C +C F SP G +C + +V C+D
Sbjct: 1864 NADCINSPGS----------YRC-ECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQ 1912
Query: 2390 SQTNC 2394
C
Sbjct: 1913 GSYQC 1917
Score = 32.0 bits (71), Expect = 8.7
Identities = 36/146 (24%), Positives = 50/146 (34%), Gaps = 17/146 (11%)
Query: 1807 PDPCRLLSSPE----ACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLR 1862
P PCR P AC C G C G+ + +G C + E ++
Sbjct: 258 PQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCE 317
Query: 1863 TCSECLARHPRTLQPG---DGEASTPRCKWCTNCPEGACIGRNGS-CTSENDCRINQREV 1918
EC ++ PG GE S + CP G +GS C + V
Sbjct: 318 DIDEC------SIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLV 371
Query: 1919 FWAGNCSEAACGAADCEQCTRE-GKC 1943
G C++ G QC E G+C
Sbjct: 372 --NGRCAQELPGRMTKMQCCCEPGRC 395
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 86.7 bits (213), Expect = 3e-16
Identities = 79/299 (26%), Positives = 113/299 (37%), Gaps = 73/299 (24%)
Query: 2132 PHGYECSCKTGYTMDNMTGLCRP-------------VCA-QGCVNGSCVEPD-HCRCHFG 2176
PHG +C CK G + LC P C+ +G ++ C + C C G
Sbjct: 797 PHGGQCLCKPG-VVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTG 855
Query: 2177 FVGRNCST------------ECRCNRHS-EC-AGVGARDHCLLCRNHTKGSHCEQCLPLF 2222
G C C CN H+ EC GA CL CR+HT G HCE+C+ F
Sbjct: 856 AFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGA---CLGCRDHTGGEHCERCIAGF 912
Query: 2223 VGS--AVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSED 2280
G GG CRPC G + ++ + E
Sbjct: 913 HGDPRLPYGGQCRPC---------------PCPEGPGSQRHFATSCHQDE-------YSQ 950
Query: 2281 EAVCVNCQNNSYGEKCESCLQGYF----LLDGKCTKCQCNGH-----ADTCNEQDGTGCP 2331
+ VC +C+ G +CE+C G+F G+C C+C+G+ D C+ G
Sbjct: 951 QIVC-HCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLR 1009
Query: 2332 CQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTS 2390
C ++TE C P + C +C + G+ QQC +C DP+S
Sbjct: 1010 CLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGT--NPQQC----PSPDQCHCDPSS 1062
Score = 81.6 bits (200), Expect = 1e-14
Identities = 72/211 (34%), Positives = 89/211 (42%), Gaps = 41/211 (19%)
Query: 1016 ARCHPRA-TCLNTP--LSYECH-CQRGYQGDGISHCNRTCLEDCGH-GVCSGPPDFT--- 1067
+ C+P CL P + C C GY G G + C + C C H G S + T
Sbjct: 793 SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC-QAC--QCSHEGALSSLCEKTSGQ 849
Query: 1068 CVCDLGWTSDLPPPTPAPGPPAPRCSRD---------CGCSFHSHCRKRGPGFCDECQDW 1118
C+C G A G RC R C C+ H+ G C C+D
Sbjct: 850 CLCRTG----------AFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
Query: 1119 TWGEHCERCRPGSFGNATGSRG--CRPCQC-NGHGDPRR----GHCDNLSG--LCFCQDH 1169
T GEHCERC G G+ G CRPC C G G R H D S +C C+
Sbjct: 900 TGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAG 959
Query: 1170 TEGAHCQLCSPGYYGDP-RAGGSC-FRECGG 1198
G C+ C+PG++GDP R GG C EC G
Sbjct: 960 YTGLRCEACAPGHFGDPSRPGGRCQLCECSG 990
Score = 73.9 bits (180), Expect = 2e-12
Identities = 94/336 (27%), Positives = 118/336 (35%), Gaps = 43/336 (12%)
Query: 940 DGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPAR 999
+G L C Q + G +E NP G+CL + G C L G P
Sbjct: 778 NGALPC----QCNPQGSLSSECNPHGGQCL---CKPGVVGRRCDLCAPGYYGFG---PTG 827
Query: 1000 WAYARCPDVDECRLGLARCHPRATCLNTPLSYEC-HCQRGYQGDGISH---CNRTCLEDC 1055
+C + + C C CQRG G CN E
Sbjct: 828 CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECN 887
Query: 1056 GH-GVCSGPPDFT----CV-CDLGWTSDLPPP-----TPAPGPPAPRCSRDCGCSFHSHC 1104
H G C G D T C C G+ D P P P P P R S H
Sbjct: 888 THTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQD- 946
Query: 1105 RKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG-CRPCQCNGHGDPRRGH-CDNLSG 1162
+ C+ G CE C PG FG+ + G C+ C+C+G+ DP CD +G
Sbjct: 947 -EYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTG 1005
Query: 1163 LCF-CQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPP 1221
C C HTEG HC C PG++G A SC R C L TN + P
Sbjct: 1006 QCLRCLHHTEGPHCAHCKPGFHGQ-AARQSCHR-CTCNLLGTNPQQCPSPDQ---CHCDP 1060
Query: 1222 GGGAARA-----GPGLSYCV---WVVSATEELQPCA 1249
G GP C W +++ QPCA
Sbjct: 1061 SSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCA 1096
Score = 71.6 bits (174), Expect = 1e-11
Identities = 105/402 (26%), Positives = 135/402 (33%), Gaps = 111/402 (27%)
Query: 2024 QCL-SPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGR 2082
QCL P + RC G GP C QA QC+ H G + + G+
Sbjct: 801 QCLCKPGVVGRRCDLCAPGYYGFGPTGC-----QACQCS------HEGALSSLCEKTSGQ 849
Query: 2083 CMEGGLSGPRDGLTCGR-PGASWAFLSCPPEDECA-NGHHD-CNETQN----CHDQPHGY 2135
C+ GL C R W F SC P C NGH D CN C D G
Sbjct: 850 CL---CRTGAFGLRCDRCQRGQWGFPSCRP---CVCNGHADECNTHTGACLGCRDHTGGE 903
Query: 2136 ECS-CKTGYTMDNMT---GLCRPV-CAQGCVNG-----SCVEPDH-----CRCHFGFVGR 2180
C C G+ D G CRP C +G + SC + ++ C C G+ G
Sbjct: 904 HCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGL 963
Query: 2181 NCST-----------------ECRCNRHSECAGVGARD----HCLLCRNHTKGSHCEQCL 2219
C C C+ + + A D CL C +HT+G HC C
Sbjct: 964 RCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCK 1023
Query: 2220 PLFVGSAVGGGTCRPCHAFCRG-NSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPS 2278
P F G A +C C G N C S P + DP +
Sbjct: 1024 PGFHGQA-ARQSCHRCTCNLLGTNPQQCPS----------PDQCHCDPSSGQ-------- 1064
Query: 2279 EDEAVCVNCQNNSYGEKCESCLQGYFLLDG--KCTKCQCN---GHADTCNEQDGTGCPCQ 2333
C N G C+ C ++ L C C C+ TCNE G C C+
Sbjct: 1065 ------CPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQ-CHCR 1117
Query: 2334 NNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCY 2375
T C++C+E G P G QC+
Sbjct: 1118 AGFGGRT----------------CSECQELHWGDP--GLQCH 1141
Score = 71.6 bits (174), Expect = 1e-11
Identities = 72/264 (27%), Positives = 93/264 (35%), Gaps = 54/264 (20%)
Query: 935 RCRSCD----GFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGL 990
RC C GF +C C+ C +E N G CL GG +C +
Sbjct: 860 RCDRCQRGQWGFPSCRPCV----CNGHADECNTHTGACL--GCRDHTGGEHCERCIAGFH 913
Query: 991 GLPVALPARWAYARCPDVDECRLGL-ARCHPRATCLNTPLSYE--CHCQRGYQGDGISHC 1047
G P LP CP C G ++ H +C S + CHC+ GY G C
Sbjct: 914 GDP-RLPYGGQCRPCP----CPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEAC 968
Query: 1048 NRTCLEDCGHGVCSGPPDFTC-VCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRK 1106
GH P C +C+ D P C H+
Sbjct: 969 AP------GHFGDPSRPGGRCQLCECSGNIDPMDPD--------------ACDPHT---- 1004
Query: 1107 RGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHG-------DPRRGHCDN 1159
G C C T G HC C+PG G A + C C CN G P + HCD
Sbjct: 1005 ---GQCLRCLHHTEGPHCAHCKPGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDP 1060
Query: 1160 LSGLCFCQDHTEGAHCQLCSPGYY 1183
SG C C + +G C C+P ++
Sbjct: 1061 SSGQCPCLPNVQGPSCDRCAPNFW 1084
Score = 70.1 bits (170), Expect = 3e-11
Identities = 43/128 (33%), Positives = 54/128 (42%), Gaps = 24/128 (18%)
Query: 1080 PPTPAPGPPAPRCSRDCGCSFHSH-CR----------KRGPGFCDECQDWTWGEHCERCR 1128
P PA + C R C C H+H C G CD CQ T G HCE CR
Sbjct: 332 PWRPAEDGHSHAC-RKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCR 390
Query: 1129 PGSFGNAT----GSRGCRPCQCNGHGDPRRGHCDN--------LSGLCFCQDHTEGAHCQ 1176
P + + T CR C C+ G G CD+ +SG C C++H G CQ
Sbjct: 391 PFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQ 450
Query: 1177 LCSPGYYG 1184
C G++G
Sbjct: 451 QCRDGFFG 458
Score = 67.0 bits (162), Expect = 2e-10
Identities = 63/207 (30%), Positives = 75/207 (36%), Gaps = 43/207 (20%)
Query: 1019 HPRATCLNTPLSYECH-CQRGYQG-------DGISHCNRTCLEDCGH------------- 1057
H C + C CQ Y+ DG SH R C E GH
Sbjct: 307 HGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKC-ECHGHTHSCHFDMAVYLA 365
Query: 1058 ------GVCSGPPDFTCV--CDLGWTSDLPPPTPAPGPPAPRCSRDC---GCSFHSHCRK 1106
GVC G T C+L PT PA S DC G C
Sbjct: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 1107 RGP-------GFCDECQDWTWGEHCERCRPGSFGNATGSR-GCRPCQCNGHGD-PRRGHC 1157
G C C++ G C++CR G FG + R GCR CQCN G P C
Sbjct: 426 HDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPC 484
Query: 1158 DNLSGLCFCQDHTEGAHCQLCSPGYYG 1184
D SG C+C+ G C C PG++G
Sbjct: 485 DPNSGSCYCKRLVTGRGCDRCLPGHWG 511
Score = 63.2 bits (152), Expect = 4e-09
Identities = 37/99 (37%), Positives = 47/99 (47%), Gaps = 16/99 (16%)
Query: 1097 GCSFHSHCRKRG--PGF--CDE------CQDWTWGEHCERCRPGSFGNATGSRGCRPCQC 1146
GC C RG PG CD C+ G C+RC PG +G + GCRPC C
Sbjct: 466 GCR-RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDC 524
Query: 1147 NGHG--DPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
+ G DP+ CD +G C C+ H G C+ PGY+
Sbjct: 525 DVGGALDPQ---CDEGTGQCHCRQHMVGRRCEQVQPGYF 560
Score = 60.8 bits (146), Expect = 2e-08
Identities = 58/216 (26%), Positives = 82/216 (37%), Gaps = 55/216 (25%)
Query: 2186 CRCNRH-SECAGV-GARDHC-------LLCRNHTKGSHCEQC------LPLFVGSAVGGG 2230
C C H SECA GA H +C+++T+G +CEQC LP
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
Query: 2231 TCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNN 2290
CR C C G++H C + ++ G V+ G VC CQ+N
Sbjct: 343 ACRKCE--CHGHTHSCHFDMAVYLASGN--------------VSGG------VCDGCQHN 380
Query: 2291 SYGEKCESCLQGYFLLD--------GKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQ 2342
+ G CE C + +F D C C C D QDG C ++ G
Sbjct: 381 TAGRHCELC-RPFFYRDPTKDLRDPAVCRSCDC----DPMGSQDGGRCDSHDDPALGLVS 435
Query: 2343 GSSPSDRRDCYKYQCAKCRESFHG----SPLGGQQC 2374
G + +C +CR+ F G LG ++C
Sbjct: 436 GQCRC-KEHVVGTRCQQCRDGFFGLSISDRLGCRRC 470
Score = 56.6 bits (135), Expect = 3e-07
Identities = 41/122 (33%), Positives = 51/122 (41%), Gaps = 36/122 (29%)
Query: 1083 PAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDW----TWGEHCERCRPGSFGNATGS 1138
PAPG PA G H RG C++CQD+ W RP G+ S
Sbjct: 294 PAPGAPAHAEGMVHGACICKH-NTRGLN-CEQCQDFYRDLPW-------RPAEDGH---S 341
Query: 1139 RGCRPCQCNGH--------------GDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYG 1184
CR C+C+GH G+ G CD CQ +T G HC+LC P +Y
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG------CQHNTAGRHCELCRPFFYR 395
Query: 1185 DP 1186
DP
Sbjct: 396 DP 397
Score = 51.2 bits (121), Expect = 1e-05
Identities = 101/410 (24%), Positives = 131/410 (31%), Gaps = 95/410 (23%)
Query: 1887 CKWCTNCPEGA----CIGRNGSCTSEND-----CRINQREVFWAGNCSEAACGAADCEQC 1937
C+ C EGA C +G C C QR + +C C E
Sbjct: 828 CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECN 887
Query: 1938 TREGKCMWTRQFKRTGETRRILS-----VQPTYDWTCFSHSLLNVSPMPVESSPPLPCPT 1992
T G C+ R R ++ + Y C P PCP
Sbjct: 888 THTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQC----------------RPCPCPE 931
Query: 1993 -PCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLS--------PSYLPLRCMAGGCGRL 2043
P TSC + + HC + +C + PS RC C
Sbjct: 932 GPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGN 991
Query: 2044 L--RGPESCSLGCAQATQCALCLRRPHCGWCAWG--GQDGGGRCMEGGLSGPRDGLTCGR 2099
+ P++C Q +C PHC C G GQ C TC
Sbjct: 992 IDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHR---------CTCNL 1042
Query: 2100 PGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSC-KTGYTMDNMTG-------L 2151
G + CP D+C H D + Q C P+ SC + N+T
Sbjct: 1043 LGTNPQ--QCPSPDQC---HCDPSSGQ-CPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCA 1096
Query: 2152 CRPVCAQGCVNGSCVE-PDHCRCHFGFVGRNCSTECR----------CNRHSECAGVGA- 2199
C P A+G +C E C C GF GR CS EC+ C+ +C G
Sbjct: 1097 CHPSRARG---PTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQCHA-CDCDSRGID 1151
Query: 2200 -------RDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGN 2242
HC CR G C+QC F G C PCHA C G+
Sbjct: 1152 TPQCHRFTGHCS-CRPGVSGVRCDQCARGFSGIF---PACHPCHA-CFGD 1196
Score = 45.1 bits (105), Expect = 0.001
Identities = 54/260 (20%), Positives = 80/260 (30%), Gaps = 91/260 (35%)
Query: 2127 NCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCST-- 2184
NC H EC+ G P A+G V+G+C+ C G NC
Sbjct: 282 NCFCYGHASECAPAPG----------APAHAEGMVHGACI------CKHNTRGLNCEQCQ 325
Query: 2185 --------------------ECRCNRHSE----------CAGVGARDHCLLCRNHTKGSH 2214
+C C+ H+ +G + C C+++T G H
Sbjct: 326 DFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRH 385
Query: 2215 CEQCLPLFVGSAV----GGGTCRPCHAFCRGNSH--ICISRKE--LQMSKGEPKKYSLDP 2266
CE C P F CR C G+ C S + L + G+
Sbjct: 386 CELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQ-------- 437
Query: 2267 EEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGK----CTKCQCNGHADTC 2322
C+ + G +C+ C G+F L C +CQCN
Sbjct: 438 ------------------CRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP 479
Query: 2323 NEQDGTGCPCQNNTETGTCQ 2342
PC N+ + C+
Sbjct: 480 G-----STPCDPNSGSCYCK 494
Score = 41.6 bits (96), Expect = 0.011
Identities = 36/104 (34%), Positives = 41/104 (39%), Gaps = 28/104 (26%)
Query: 129 NLLGFNASFRFSLCPGGCQSHGQCQPP-GVCACEPGWGGPDC--------------GLQE 173
NLLG N CP Q H C P G C C P GP C G Q
Sbjct: 1041 NLLGTNPQ----QCPSPDQCH--CDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQP 1094
Query: 174 CSAYCG-SHG-TCASPLGPCRCEPGFLGRAC----DLHLWENQG 211
C+ + + G TC G C C GF GR C +LH W + G
Sbjct: 1095 CACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELH-WGDPG 1137
Score = 40.4 bits (93), Expect = 0.025
Identities = 26/84 (30%), Positives = 31/84 (36%), Gaps = 18/84 (21%)
Query: 1345 PGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAG----------- 1393
P CP P +C + G C C GP C P N +G G
Sbjct: 1047 PQQCPSPDQCHCDPSS---GQCPCLPNVQGPSCDRC-APNFWNLTSGHGCQPCACHPSRA 1102
Query: 1394 ---TCNQSLGVCICAEGFGGPDCA 1414
TCN+ G C C GFGG C+
Sbjct: 1103 RGPTCNEFTGQCHCRAGFGGRTCS 1126
Score = 40.0 bits (92), Expect = 0.032
Identities = 73/318 (22%), Positives = 103/318 (32%), Gaps = 66/318 (20%)
Query: 1144 CQCNGHGD---PRRG---HCDNL-SGLCFCQDHTEGAHCQLCS---------PGYYGDPR 1187
C C GH P G H + + G C C+ +T G +C+ C P G
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
Query: 1188 AGGSCFRECGGRALLTNVS-SVALGSRRVGGLLPPGGGAARAGPGLSYC--VWVVSATEE 1244
A C EC G + +V L S V G + G AG C + T++
Sbjct: 343 ACRKC--ECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
Query: 1245 LQPCAP--GTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQ 1302
L+ A C P+ S D C + D L +G + ++ C Q
Sbjct: 401 LRDPAVCRSCDCDPMG---SQDGGR-CD-----SHDDPALGLVSGQCRCKEHVVGTRCQQ 451
Query: 1303 RRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA-- 1360
RD G + +G RC G+ P C P G+
Sbjct: 452 CRD-------------------GFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCY 492
Query: 1361 -----AGAGLCRC-PQGWAGPHCRMALCPENCNAHTGAG-TCNQSLGVCICAEGFGGPDC 1413
G G RC P W H + P +C+ C++ G C C + G C
Sbjct: 493 CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
Query: 1414 ATKLDG------GQLVWE 1425
G L+WE
Sbjct: 553 EQVQPGYFRPFLDHLIWE 570
Score = 40.0 bits (92), Expect = 0.032
Identities = 40/162 (24%), Positives = 56/162 (34%), Gaps = 45/162 (27%)
Query: 2157 AQGCVNGSCVEPDHC------RCHFGFVGRNCSTE-----CRCNRHSECAGVGARDH--- 2202
A G V+G C +H +C GF G + S C+CN G D
Sbjct: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
Query: 2203 CLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKY 2262
C+ G C++CLP G + CRPC G
Sbjct: 490 SCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGG--------------------- 528
Query: 2263 SLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF 2304
+LDP+ EG + +C+ + G +CE GYF
Sbjct: 529 ALDPQ-----CDEGTGQ-----CHCRQHMVGRRCEQVQPGYF 560
Score = 35.0 bits (79), Expect = 1.0
Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 15/63 (23%)
Query: 156 GVCACEPGWGGPDC-----------GLQECSAYCGSHGT----CASPLGPCRCEPGFLGR 200
G C C G+GG C GLQ + C S G C G C C PG G
Sbjct: 1112 GQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGV 1171
Query: 201 ACD 203
CD
Sbjct: 1172 RCD 1174
Score = 33.1 bits (74), Expect = 3.9
Identities = 23/68 (33%), Positives = 25/68 (36%), Gaps = 10/68 (14%)
Query: 146 CQSHG-QCQ-PPGVCA-----CEPGW---GGPDCGLQECSAYCGSHGTCASPLGPCRCEP 195
C HG QC PGV C PG+ G C +CS C G C C
Sbjct: 795 CNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRT 854
Query: 196 GFLGRACD 203
G G CD
Sbjct: 855 GAFGLRCD 862
Score = 32.3 bits (72), Expect = 6.7
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 6/30 (20%)
Query: 175 SAYCGSHGTCASPLGPCRCEPGFLGRACDL 204
S+ C HG G C C+PG +GR CDL
Sbjct: 792 SSECNPHG------GQCLCKPGVVGRRCDL 815
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 86.7 bits (213), Expect = 3e-16
Identities = 67/209 (32%), Positives = 81/209 (38%), Gaps = 48/209 (22%)
Query: 1033 CHCQRGYQGDGISHCNRTCLEDC--------------GHGVCSGPPDFTCV--------- 1069
C C Y+GD C D GH P CV
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGA 1890
Query: 1070 ----CDLGWTSDLPPPTPAPGPPAPRCSRDCGCS-----FHSHCRKRGPGFCDECQDWTW 1120
C G+ S P+ AP S C S F C RG C+
Sbjct: 1891 HCERCQAGFVSSRDDPS------APCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYA 1944
Query: 1121 GEHCERCRPGSFGN--ATGSRGCRPCQCNGHGDPRR--GHCDNLSGLC-FCQDHTEGAHC 1175
G CERC PG FGN GS C+PC C+G+GDP CD L+G C C HT G C
Sbjct: 1945 GASCERCAPGFFGNPLVLGS-SCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC 2003
Query: 1176 QLCSPGYYGDPRAGGSCFR----ECGGRA 1200
++C+PG+YG+ G+C R CG A
Sbjct: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTEA 2032
Score = 78.6 bits (192), Expect = 8e-14
Identities = 97/396 (24%), Positives = 133/396 (33%), Gaps = 95/396 (23%)
Query: 1055 CGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHS-HC-------RK 1106
C H C G D C G+ P PA A C + C C H+ C R+
Sbjct: 324 CQHNTCGGTCDRCCP---GFNQQ--PWKPATANSANEC-QSCNCYGHATDCYYDPEVDRR 377
Query: 1107 R----------GPGFCDECQDWTWGEHCERCRPGSFGNAT----GSRGCRPCQCNGHGDP 1152
R G G C +CQ T G +CERC PG + + CR C C D
Sbjct: 378 RASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCES--DF 435
Query: 1153 RRGHCDNLSGLCFCQDHTEGAHCQLCSPGY------YGDPRAGGSCFRECGGRALLTNVS 1206
G C++L+G C+C+ + G C +C+ G+ Y P + + + N
Sbjct: 436 TDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCD 495
Query: 1207 SVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSS 1266
A G++ G A R P + C+ +P GT C F
Sbjct: 496 CSAAGTQ---------GNACRKDPRVGRCL--------CKPNFQGTHCELCAPGFYGPGC 538
Query: 1267 TPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGS 1326
PC S D DTG + A C +
Sbjct: 539 QPCQCSSPGVADD-RCDPDTGQCRCRVGFEGATCDR------------------------ 573
Query: 1327 SSWGFNASVGSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCP--- 1383
+ G+ CG G+ P +G AG C C +AGPHC
Sbjct: 574 CAPGYFHFPLCQLCGCSPAGTLP--------EGCDEAGRCLCQPEFAGPHCDRCRPGYHG 625
Query: 1384 -ENCNAHT--GAGTCNQ---SLGVCICAEGFGGPDC 1413
NC A T G +Q + G+C C G+ G C
Sbjct: 626 FPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTAC 661
Score = 76.3 bits (186), Expect = 4e-13
Identities = 143/601 (23%), Positives = 177/601 (29%), Gaps = 146/601 (24%)
Query: 888 TCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGF----- 942
TC+ C +Q W +T Y H +D V +S DG
Sbjct: 332 TCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGG 391
Query: 943 -----------LTCHECLQS------------HECGWCGNEDNPTLGRCLQGDFSGP--- 976
+ C CL H C C E + T G C D +G
Sbjct: 392 VCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTC--EDLTGRCYC 449
Query: 977 ---LGGGNCSLWVGEGLGLPVALPA-------RWAYARCPDVDECRLGLARCHPRATCLN 1026
G C + G P P R + C A A C
Sbjct: 450 RPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA-CRK 508
Query: 1027 TPLSYECHCQRGYQGDGISHCNRTCLEDCGHGV----CSGP--------PDF-TCVCDLG 1073
P C C+ +QG +HC G G CS P PD C C +G
Sbjct: 509 DPRVGRCLCKPNFQG---THCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVG 565
Query: 1074 WTSDLPPPTPAPGP-PAPRCSRDCGCSFHSHCRKRGPGFCDE-----CQDWTWGEHCERC 1127
+ APG P C CGCS P CDE CQ G HC+RC
Sbjct: 566 FEGATCDRC-APGYFHFPLCQL-CGCSPAGTL----PEGCDEAGRCLCQPEFAGPHCDRC 619
Query: 1128 RPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNL---SGLCFCQDHTEGAHCQLCSPGYYG 1184
RPG G C+ C C DPR G D L GLC C+ G CQ CSPG++G
Sbjct: 620 RPGYHGFPN----CQACTC----DPR-GALDQLCGAGGLCRCRPGYTGTACQECSPGFHG 670
Query: 1185 DP-------RAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVW 1237
P A GS C R+ + G R PG YC
Sbjct: 671 FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLR--CDTCVPG------AYNFPYC-- 720
Query: 1238 VVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIA 1297
E C P L P P++ PC
Sbjct: 721 ------EAGSCHPAGLAP--VDPALPEAQVPC---------------------------- 744
Query: 1298 AFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSC-PVPQECVP 1356
C + P + G W + S+ G R GG C P +C
Sbjct: 745 -MCRAHVEGPSCDRCKPGF----WGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFC 799
Query: 1357 QDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAG---TCNQSLGVCICAEGFGGPDC 1413
+ G C G+ G +C G +C GVC C GP C
Sbjct: 800 KPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTC 859
Query: 1414 A 1414
+
Sbjct: 860 S 860
Score = 74.7 bits (182), Expect = 1e-12
Identities = 90/324 (27%), Positives = 116/324 (35%), Gaps = 47/324 (14%)
Query: 1121 GEHCERCRPGSFGNATGS--RGCRPCQCNGHGDPRRGHCDNLSGLCF-CQDHTEGAHCQL 1177
G+ C+ C PG + + G C PCQC+GH D C SG+C CQ +TEGAHC+
Sbjct: 1839 GDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSD----RCLPGSGVCVDCQHNTEGAHCER 1894
Query: 1178 CSPGYYG---DPRAGG-SCFRECGGRALLTNVSS-VALGSRRVGGLLPPGGGAA---RAG 1229
C G+ DP A SC C N + L R L PG A R
Sbjct: 1895 CQAGFVSSRDDPSAPCVSC--PCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCA 1952
Query: 1230 PGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDG------FPRF 1283
PG V+ ++ QPC P L D T + G P F
Sbjct: 1953 PGFFGNPLVLGSS--CQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGF 2010
Query: 1284 LDTGVVQSDRSLIAAF-CGQRRDRPLTVQAL--SGLLVLHWEANGSSSWGFNASVGS--A 1338
++ + + CG P + L +G+ + +GF+ G
Sbjct: 2011 YGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCRPC 2070
Query: 1339 RCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCR------MALCPENC-NAHTG 1391
CG GS EC PQ G C C G GP CR L + C
Sbjct: 2071 ACGPAAEGS-----ECHPQSGQ-----CHCRPGTMGPQCRECAPGYWGLPEQGCRRCQCP 2120
Query: 1392 AGTCNQSLGVCICAEGFGGPDCAT 1415
G C+ G C C G G C T
Sbjct: 2121 GGRCDPHTGRCNCPPGLSGERCDT 2144
Score = 71.6 bits (174), Expect = 1e-11
Identities = 92/333 (27%), Positives = 114/333 (34%), Gaps = 98/333 (29%)
Query: 2128 CHDQPHGYECS-CKTGYTMDN---MTGLCRPVCAQG----CVNGS--CV------EPDHC 2171
C G C C G+ D G C P G C+ GS CV E HC
Sbjct: 1833 CPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHC 1892
Query: 2172 -RCHFGFVGRNCSTECRC-----------NRHSE-CAGVGARDHCLLCRNHTKGSHCEQC 2218
RC GFV C N +E C G R CL C+ G+ CE+C
Sbjct: 1893 ERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL-CKPGYAGASCERC 1951
Query: 2219 LPLFVGSA-VGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGP 2277
P F G+ V G +C+PC C GN G+P D + +
Sbjct: 1952 APGFFGNPLVLGSSCQPCD--CSGN--------------GDPNLLFSDCDPLTG------ 1989
Query: 2278 SEDEAVCVNCQNNSYGEKCESCLQGYF---LLDGKCTKCQC-----------NGH----- 2318
C C ++ G +CE C G++ LL G CT+C C +GH
Sbjct: 1990 -----ACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKA 2044
Query: 2319 ------ADTCNEQ----DGTG----CPCQNNTETGTC--QGSSPSDRRDCYKYQCAKCRE 2362
D C E DG G C C E C Q R QC +C
Sbjct: 2045 GVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAP 2104
Query: 2363 SFHGSPLGGQQCYRLISVEQECCLDP-TSQTNC 2394
+ G P Q C R C DP T + NC
Sbjct: 2105 GYWGLP--EQGCRRCQCPGGRC--DPHTGRCNC 2133
Score = 70.5 bits (171), Expect = 2e-11
Identities = 82/305 (26%), Positives = 106/305 (34%), Gaps = 71/305 (23%)
Query: 944 TCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYA 1003
+C EC G+ + LGRC+ G C G G+ V A
Sbjct: 1841 SCQECAP----GFYRDVKGLFLGRCVPCQCHGH--SDRCL----PGSGVCVDCQHNTEGA 1890
Query: 1004 RCPDVDECRLGL--ARCHPRATCLNTPLSY------------------ECHCQRGYQGDG 1043
C + C+ G +R P A C++ P +C C+ GY G
Sbjct: 1891 HC---ERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
Query: 1044 ISHC------NRTCL-EDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPA-----PGPPAPR 1091
C N L C CSG D + SD P T A PR
Sbjct: 1948 CERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLF-----SDCDPLTGACRGCLRHTTGPR 2002
Query: 1092 CSRDCGCSFHSH-----------CRKRGPGFCDE------CQDWTWGEHCERCRPGSFGN 1134
C C F+ + C G CD C+ G C+RC+ G FG
Sbjct: 2003 CEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFG- 2060
Query: 1135 ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFR 1194
G GCRPC C + C SG C C+ T G C+ C+PGY+G P G +
Sbjct: 2061 FDGCGGCRPCACGPAAEG--SECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRCQ 2118
Query: 1195 ECGGR 1199
GGR
Sbjct: 2119 CPGGR 2123
Score = 68.2 bits (165), Expect = 1e-10
Identities = 143/563 (25%), Positives = 183/563 (32%), Gaps = 165/563 (29%)
Query: 1846 SPCSPMPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRC--------KWCTNCPEGA 1897
SP P+ SP CRR S+ G E T RC + C C EG
Sbjct: 415 SPNHPLD-SPHVCRRCNCESD--------FTDGTCEDLTGRCYCRPNFSGERCDVCAEG- 464
Query: 1898 CIGRNGSC----TSENDCRINQREVFWAGNCSEAACGAAD-----CEQCTREGKCMWTRQ 1948
SC +S ND R +V AG C AA C + R G+C+
Sbjct: 465 -FTGFPSCYPTPSSSNDTR---EQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPN 520
Query: 1949 FKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKG 2008
F+ T L Y C P + S P C P+ C G
Sbjct: 521 FQGT---HCELCAPGFYGPGC----------QPCQCSSPGVADDRCD--PDTGQCRCRVG 565
Query: 2009 ADGGWQHCVWSSSLQQCLSPSYL--PLRCMAGGCGRLLRGPESCSLGCAQATQCALC--- 2063
+G ++ +C +P Y PL C GC PE GC +A +C LC
Sbjct: 566 FEG--------ATCDRC-APGYFHFPL-CQLCGCSPAGTLPE----GCDEAGRC-LCQPE 610
Query: 2064 LRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLT--CGRPGASWAFLSCPPE------DEC 2115
PHC C G G C + PR L CG G C P EC
Sbjct: 611 FAGPHCDRCR-PGYHGFPNC-QACTCDPRGALDQLCGAGG----LCRCRPGYTGTACQEC 664
Query: 2116 ANGHHDCNETQNCHDQ----------PHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSC 2165
+ G H CH P +CSC+ +TGL C G N
Sbjct: 665 SPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRP-----RVTGLRCDTCVPGAYNFPY 719
Query: 2166 VEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCL-------LCRNHTKGSHCEQC 2218
E C AG+ D L +CR H +G C++C
Sbjct: 720 CEAGSCHP---------------------AGLAPVDPALPEAQVPCMCRAHVEGPSCDRC 758
Query: 2219 LPLFVG-SAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGP 2277
P F G S C C RG E Q G+
Sbjct: 759 KPGFWGLSPSNPEGCTRCSCDLRGTLG---GVAECQPGTGQ------------------- 796
Query: 2278 SEDEAVCVNCQNNSYGEKCESCLQGYFLLDGK----CTKCQCN---GHADTCNEQDGTGC 2330
C C+ + G+ C SC G+F LD C C+C+ +C + G C
Sbjct: 797 ------CF-CKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGV-C 848
Query: 2331 PCQNNTETGTCQGSSPSDRRDCY 2353
C+ NT+ TC S P+ RD Y
Sbjct: 849 RCRPNTQGPTC--SEPA--RDHY 867
Score = 68.2 bits (165), Expect = 1e-10
Identities = 57/197 (28%), Positives = 77/197 (39%), Gaps = 38/197 (19%)
Query: 1018 CHP---RATCLNTPLSYEC-HCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLG 1073
C P + C + +C C GY G +C R C DCG +C C+C
Sbjct: 1450 CEPFGGQCPCHAHVIGRDCSRCATGYWG--FPNC-RPC--DCGARLCDELTG-QCICP-- 1501
Query: 1074 WTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGF-------CD------ECQDWTW 1120
+PP P C GC C GPG CD +C+
Sbjct: 1502 -PRTIPPDCLLCQPQTFGCHPLVGCE---ECNCSGPGIQELTDPTCDTDSGQCKCRPNVT 1557
Query: 1121 GEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSP 1180
G C+ C PG G CRPC C+ G G CD L+G C+C+++ +G C CS
Sbjct: 1558 GRRCDTCSPGFHGYPR----CRPCDCHEAGTAP-GVCDPLTGQCYCKENVQGPKCDQCSL 1612
Query: 1181 GYY----GDPRAGGSCF 1193
G + +P+ CF
Sbjct: 1613 GTFSLDAANPKGCTRCF 1629
Score = 66.2 bits (160), Expect = 4e-10
Identities = 67/233 (28%), Positives = 81/233 (34%), Gaps = 56/233 (24%)
Query: 967 RCLQGDFSGPLG-GGNCSLWVGEGLGLPVALPARWAYARC-PDVDECRLGLARCHPRATC 1024
RC G F PL G +C G G P L ++ C P CR C
Sbjct: 1950 RCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL-----FSDCDPLTGACR----------GC 1994
Query: 1025 LNTPLSYECH-CQRGYQGDGI--SHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPP 1081
L C C G+ G+ + +C R CG C P C+C G T
Sbjct: 1995 LRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEACD-PHSGHCLCKAGVT------ 2047
Query: 1082 TPAPGPPAPRCS------------RDCGC---SFHSHCRKRGPGFCDECQDWTWGEHCER 1126
G RC R C C + S C + G C C+ T G C
Sbjct: 2048 ----GRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQS-GQC-HCRPGTMGPQCRE 2101
Query: 1127 CRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCS 1179
C PG +G +GCR CQC G G CD +G C C G C CS
Sbjct: 2102 CAPGYWG--LPEQGCRRCQCPG------GRCDPHTGRCNCPPGLSGERCDTCS 2146
Score = 62.4 bits (150), Expect = 6e-09
Identities = 43/142 (30%), Positives = 50/142 (35%), Gaps = 25/142 (17%)
Query: 1110 GFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDH 1169
G C C T G CE C PG +GNA C C C G CD SG C C+
Sbjct: 1989 GACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA---CDPHSGHCLCKAG 2045
Query: 1170 TEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAG 1229
G C C G++G F CGG A G G P G
Sbjct: 2046 VTGRRCDRCQEGHFG--------FDGCGG------CRPCACGPAAEGSECHPQSGQCHCR 2091
Query: 1230 PGLSYCVWVVSATEELQPCAPG 1251
PG + + + CAPG
Sbjct: 2092 PG--------TMGPQCRECAPG 2105
Score = 60.1 bits (144), Expect = 3e-08
Identities = 85/362 (23%), Positives = 119/362 (32%), Gaps = 90/362 (24%)
Query: 2019 SSSLQQCLSP-SYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQ 2077
+S+++ CL P SY C G R + LG +C C H C
Sbjct: 1825 ASNVELCLCPASYRGDSCQECAPG-FYRDVKGLFLG-----RCVPCQCHGHSDRCL---- 1874
Query: 2078 DGGGRCME-------GGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHD 2130
G G C++ + G R S +SCP C N + C
Sbjct: 1875 PGSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCP----CPLSVPSNNFAEGCVL 1930
Query: 2131 QPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNR 2190
+ +C CK GY G CA G V +G +C C C+
Sbjct: 1931 RGGRTQCLCKPGYA-----GASCERCAPGFFGNPLV-----------LGSSCQP-CDCSG 1973
Query: 2191 H-------SECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNS 2243
+ S+C + C C HT G CE C P F G+A+ G C C G
Sbjct: 1974 NGDPNLLFSDCDPLTGA--CRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCG-- 2029
Query: 2244 HICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGY 2303
TE C+ C+ G +C+ C +G+
Sbjct: 2030 ------------------------------TEACDPHSGHCL-CKAGVTGRRCDRCQEGH 2058
Query: 2304 FLLD--GKCTKCQCNGHAD--TCNEQDGTGCPCQNNTETGTCQGSSPS----DRRDCYKY 2355
F D G C C C A+ C+ Q G C C+ T C+ +P + C +
Sbjct: 2059 FGFDGCGGCRPCACGPAAEGSECHPQSGQ-CHCRPGTMGPQCRECAPGYWGLPEQGCRRC 2117
Query: 2356 QC 2357
QC
Sbjct: 2118 QC 2119
Score = 59.7 bits (143), Expect = 4e-08
Identities = 41/119 (34%), Positives = 48/119 (40%), Gaps = 25/119 (21%)
Query: 1090 PRCSRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCERCRPGSFGNATGSRGCRP 1143
P C R C C G CDE C T C C+P +FG GC
Sbjct: 1479 PNC-RPCDC---------GARLCDELTGQCICPPRTIPPDCLLCQPQTFG-CHPLVGCEE 1527
Query: 1144 CQCNGHG-----DPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECG 1197
C C+G G DP CD SG C C+ + G C CSPG++G PR E G
Sbjct: 1528 CNCSGPGIQELTDPT---CDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAG 1583
Score = 59.3 bits (142), Expect = 5e-08
Identities = 54/207 (26%), Positives = 83/207 (40%), Gaps = 51/207 (24%)
Query: 2186 CRCNRHSE-CAGVGARDHCLL---CRNHTKGSHCEQCLPLF------VGSAVGGGTCRPC 2235
C C+ H++ C D L C+++T G C++C P F +A C+ C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 2236 HAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEK 2295
+ C G++ C E+ + SLD G + VC++CQ+++ G
Sbjct: 360 N--CYGHATDCYYDPEVDRRRASQ---SLD----------GTYQGGGVCIDCQHHTTGVN 404
Query: 2296 CESCLQGYFL-----LDGK--CTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSD 2348
CE CL G++ LD C +C C E D T C++ T C+ + +
Sbjct: 405 CERCLPGFYRSPNHPLDSPHVCRRCNC--------ESDFTDGTCEDLTGRCYCRPNFSGE 456
Query: 2349 RRDCYKYQCAKCRESFHGSPLGGQQCY 2375
R C C E F G P CY
Sbjct: 457 R-------CDVCAEGFTGFP----SCY 472
Score = 50.8 bits (120), Expect = 2e-05
Identities = 59/233 (25%), Positives = 78/233 (33%), Gaps = 80/233 (34%)
Query: 2128 CHDQPHGYECS-CKTGY--------------TMDNMTGLCRPVCAQGCVNGSCV--EPDH 2170
CH G +CS C TGY D +TG C +C + C+ +P
Sbjct: 1459 CHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQC--ICPPRTIPPDCLLCQPQT 1516
Query: 2171 CRCH--FGFVGRNCS-------TECRCNRHS-ECAGVGARDHCLLCRNHTKGSHCEQCLP 2220
CH G NCS T+ C+ S +C CR + G C+ C P
Sbjct: 1517 FGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCK----------CRPNVTGRRCDTCSP 1566
Query: 2221 LFVGSAVGGGTCRPCHAFCRGNSH-ICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE 2279
F G CRPC G + +C DP + +
Sbjct: 1567 GFHGYP----RCRPCDCHEAGTAPGVC------------------DPLTGQCY------- 1597
Query: 2280 DEAVCVNCQNNSYGEKCESCLQGYFLLDGK----CTKCQCNGHADTCNEQDGT 2328
C+ N G KC+ C G F LD CT+C C G + C T
Sbjct: 1598 -------CKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYT 1643
Score = 44.7 bits (104), Expect = 0.001
Identities = 30/84 (35%), Positives = 34/84 (40%), Gaps = 19/84 (22%)
Query: 137 FRFSLCP-GGCQSHGQ----CQPPGVCACEPGWGGPDC--------GLQECSA-YCGSHG 182
F F LC GC G C G C C+P + GP C G C A C G
Sbjct: 579 FHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRG 638
Query: 183 T----CASPLGPCRCEPGFLGRAC 202
C + G CRC PG+ G AC
Sbjct: 639 ALDQLCGAG-GLCRCRPGYTGTAC 661
Score = 43.5 bits (101), Expect = 0.003
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 12/95 (12%)
Query: 1328 SWGFNASVGSARCGSGGPG-------SCPVPQ-ECVPQDGAAGAGLCRCPQGWAG-PHCR 1378
++G + VG C GPG +C +C + G C G+ G P CR
Sbjct: 1516 TFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCR 1575
Query: 1379 MALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDC 1413
C E A T G C+ G C C E GP C
Sbjct: 1576 PCDCHE---AGTAPGVCDPLTGQCYCKENVQGPKC 1607
Score = 42.4 bits (98), Expect = 0.006
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 5/48 (10%)
Query: 2312 KCQCNGHADTCNEQDGTG-----CPCQNNTETGTCQGSSPSDRRDCYK 2354
+C C+GHAD C+ +D T C CQ+NT GTC P + +K
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWK 346
Score = 42.0 bits (97), Expect = 0.008
Identities = 30/86 (34%), Positives = 32/86 (37%), Gaps = 20/86 (23%)
Query: 137 FRFSLCPGGCQ--------SHGQCQPP-GVCACEPGWGGPDC--------GLQE--CSAY 177
F F C GGC+ +C P G C C PG GP C GL E C
Sbjct: 2059 FGFDGC-GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQGCRRC 2117
Query: 178 CGSHGTCASPLGPCRCEPGFLGRACD 203
G C G C C PG G CD
Sbjct: 2118 QCPGGRCDPHTGRCNCPPGLSGERCD 2143
Score = 41.6 bits (96), Expect = 0.011
Identities = 18/44 (40%), Positives = 22/44 (50%)
Query: 160 CEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRACD 203
C PG+ GP C +CS+ + C G CRC GF G CD
Sbjct: 529 CAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD 572
Score = 41.2 bits (95), Expect = 0.014
Identities = 85/350 (24%), Positives = 100/350 (28%), Gaps = 127/350 (36%)
Query: 1977 VSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCL-SPSYLPL-- 2033
VS S+P + CP P + N A+G CV QCL P Y
Sbjct: 1900 VSSRDDPSAPCVSCPCPLSVPSN-------NFAEG----CVLRGGRTQCLCKPGYAGASC 1948
Query: 2034 -RCMAGGCGRLLRGPESCS--------------LGCAQAT-QCALCLRR---PHCGWCAW 2074
RC G G L SC C T C CLR P C CA
Sbjct: 1949 ERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAP 2008
Query: 2075 GGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHG 2134
G G + G D CG T+ C PH
Sbjct: 2009 GFY---GNALLPGNCTRCDCTPCG--------------------------TEAC--DPHS 2037
Query: 2135 YECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCN---RH 2191
C CK G +TG C +G HFGF G C C
Sbjct: 2038 GHCLCKAG-----VTGRRCDRCQEG--------------HFGFDGCGGCRPCACGPAAEG 2078
Query: 2192 SECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKE 2251
SEC + HC R T G C +C P + G G CR C C G
Sbjct: 2079 SECHPQSGQCHC---RPGTMGPQCRECAPGYWGLPEQG--CRRCQ--CPG---------- 2121
Query: 2252 LQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQ 2301
G + NC GE+C++C Q
Sbjct: 2122 ------------------------GRCDPHTGRCNCPPGLSGERCDTCSQ 2147
Score = 40.4 bits (93), Expect = 0.025
Identities = 21/65 (32%), Positives = 23/65 (35%), Gaps = 13/65 (20%)
Query: 152 CQPPGVCACEPGWGG-------------PDCGLQECSAYCGSHGTCASPLGPCRCEPGFL 198
C G+C C PG+ G P C CSA H C G C C P
Sbjct: 644 CGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVT 703
Query: 199 GRACD 203
G CD
Sbjct: 704 GLRCD 708
Score = 39.3 bits (90), Expect = 0.055
Identities = 80/312 (25%), Positives = 96/312 (30%), Gaps = 74/312 (23%)
Query: 1843 CGGSPCSPMPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGA---CI 1899
CG SP +P +E R E H +P G P C+ CT P GA
Sbjct: 587 CGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRP--GYHGFPNCQACTCDPRGALDQLC 644
Query: 1900 GRNGSCTSENDCRINQREVFWAGNCSEAACGAADCEQC-------------TREGKCMWT 1946
G G C CR CS G C C R G+C
Sbjct: 645 GAGGLCR----CRPGYTGTA-CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCR 699
Query: 1947 RQFKRTGETRRILSVQPTYDWT-CFSHSLLNVSPMPVESSPP---LPCPTPCHLL-PNCT 2001
R R V Y++ C + S PV+ + P +PC H+ P+C
Sbjct: 700 ---PRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD 756
Query: 2002 SCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCG--RLLRGPESCSLGCAQATQ 2059
C G W LSPS P C C L G C G Q
Sbjct: 757 RC-----KPGFWG-----------LSPSN-PEGCTRCSCDLRGTLGGVAECQPGTGQ--- 796
Query: 2060 CALCLRRPH-CGWCAWGGQDG-------------GGRCMEGGLSG----PRDGLTCGRPG 2101
C +PH CG +DG RC GG G PR G+ RP
Sbjct: 797 ---CFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPN 853
Query: 2102 ASWAFLSCPPED 2113
S P D
Sbjct: 854 TQGPTCSEPARD 865
Score = 39.3 bits (90), Expect = 0.055
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 9/79 (11%)
Query: 1336 GSARCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQG-WAGPHCRMALCPENCNAHTGAGT 1394
G G+ GP P +C G RC G W P+CR C GA
Sbjct: 1439 GCHEVGATGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDC--------GARL 1490
Query: 1395 CNQSLGVCICAEGFGGPDC 1413
C++ G CIC PDC
Sbjct: 1491 CDELTGQCICPPRTIPPDC 1509
Score = 38.1 bits (87), Expect = 0.12
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 11/69 (15%)
Query: 144 GGCQSHGQCQPPGVCACEPGWGG--PDCGLQECSAYCGSHG-------TCASPLGPCRCE 194
G C + PP C+P G P G +EC+ C G TC + G C+C
Sbjct: 1496 GQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECN--CSGPGIQELTDPTCDTDSGQCKCR 1553
Query: 195 PGFLGRACD 203
P GR CD
Sbjct: 1554 PNVTGRRCD 1562
Score = 34.3 bits (77), Expect = 1.8
Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 1144 CQCNGHGDP--RRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDP 1186
C C+GH D + D C CQ +T G C C PG+ P
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQP 344
Score = 32.0 bits (71), Expect = 8.7
Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 8/65 (12%)
Query: 146 CQSHGQCQPPGVCACEPG-WGGPDCGLQECS-AYCGSHGT------CASPLGPCRCEPGF 197
C + P C+PG WG + C+ C GT C G C C+P
Sbjct: 744 CMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHV 803
Query: 198 LGRAC 202
G+AC
Sbjct: 804 CGQAC 808
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 85.9 bits (211), Expect = 5e-16
Identities = 94/369 (25%), Positives = 135/369 (36%), Gaps = 77/369 (20%)
Query: 1856 EECRRLRTC--SECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRI 1913
E C +TC S L R + GD C+ CT C GA R SC N C
Sbjct: 265 ENCHCEKTCQVSGLLYRDQDSWVDGD------HCRNCT-CKSGAVECRRMSCPPLN-CSP 316
Query: 1914 NQREVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHS 1973
+ V AG C C+ C KC++ K E +RIL+ C
Sbjct: 317 DSLPVHIAGQC---------CKVC--RPKCIYGG--KVLAEGQRILTKSCR---ECRGGV 360
Query: 1974 LLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGAD--------GGWQHCV-WSSSLQQ 2024
L+ ++ M PPL C H+LP C +G + G C W++
Sbjct: 361 LVKITEM----CPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATC 416
Query: 2025 CLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCM 2084
Y+ ++ + C + + C+ +C+ P C C+
Sbjct: 417 ECKSGYISVQGDSAYCEDI----DECAAKMHYCHANTVCVNLPGLYRCD---------CV 463
Query: 2085 EGGLSGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYT 2144
G + SC DEC +G H+C+E C + G+ C+CK GY
Sbjct: 464 PGYIRVDD--------------FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYV 509
Query: 2145 MDNMTGLCRPVCAQGC-VNGSCVEPDHCRCHFGFVGRNCS---TECRCNRH-----SECA 2195
+ +CR C +GC G+CV P+ C C GF G +C EC H S C
Sbjct: 510 GNGT--ICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSACI 567
Query: 2196 GVGARDHCL 2204
+ CL
Sbjct: 568 NLAGGFDCL 576
Score = 54.7 bits (130), Expect = 1e-06
Identities = 74/284 (26%), Positives = 91/284 (32%), Gaps = 53/284 (18%)
Query: 919 PHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLG 978
P C D + CR C G C E + E C N + C G S
Sbjct: 369 PPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGD 428
Query: 979 GGNC--------SLWVGEGLGLPVALPARW------AYAR-----CPDVDECRLGLARCH 1019
C + + V LP + Y R C + DEC G C
Sbjct: 429 SAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCD 488
Query: 1020 PRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGH-GVCSGPPDFTCVCDLGWT-SD 1077
A C NT + C C+ GY G+G + C C E C + G C P CVC G+T S
Sbjct: 489 ENAICTNTVQGHSCTCKPGYVGNG-TICRAFCEEGCRYGGTCVAPN--KCVCPSGFTGSH 545
Query: 1078 LPPPTPAPGPPAPRCSRDCGC-----SFHSHCRKRGPGFCDEC----------QDWTWGE 1122
C D C F C GP +C Q WT E
Sbjct: 546 CEKDIDECALRTHTCWNDSACINLAGGFDCLC-PSGPSCSGDCPHEGGLKHNGQVWTLKE 604
Query: 1123 HCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFC 1166
+RC S + G CR C+ C N S FC
Sbjct: 605 --DRCSVCSCKD--GKIFCRRTACD---------CQNPSADLFC 635
Score = 35.4 bits (80), Expect = 0.79
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 7/70 (10%)
Query: 134 NASFRFSLCPGGCQSHGQCQPPGVCACEPGWGGPDC--GLQECSA---YCGSHGTCASPL 188
N + + C GC+ G C P C C G+ G C + EC+ C + C +
Sbjct: 511 NGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWNDSACINLA 570
Query: 189 G--PCRCEPG 196
G C C G
Sbjct: 571 GGFDCLCPSG 580
Score = 33.5 bits (75), Expect = 3.0
Identities = 24/77 (31%), Positives = 30/77 (38%), Gaps = 7/77 (9%)
Query: 1366 CRCPQGWAGPH--CRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQLV 1423
C C G+ G CR A C E C GTC + C+C GF G C +D L
Sbjct: 502 CTCKPGYVGNGTICR-AFCEEGCRY---GGTC-VAPNKCVCPSGFTGSHCEKDIDECALR 556
Query: 1424 WETLMDSRLSADTASRF 1440
T + + A F
Sbjct: 557 THTCWNDSACINLAGGF 573
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 85.9 bits (211), Expect = 5e-16
Identities = 71/223 (31%), Positives = 89/223 (39%), Gaps = 55/223 (24%)
Query: 1006 PDVDECRLGLARCHPRATCLNT----PLSYEC--------------------HCQRGYQG 1041
P+ E R+ L R P A N LS EC HCQR G
Sbjct: 48 PETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNTTG 107
Query: 1042 DGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFH 1101
+ HC + CL+ G P F P P P P + C
Sbjct: 108 E---HCEK-CLDGYIGDSIRGAPQFC------------QPCPCPLPHLANFAESC----- 146
Query: 1102 SHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNAT--GSRGCRPCQCNGHGDPRR--GHC 1157
RK G C C + G +CERC PG +GN GS C+ C C+G+ DP C
Sbjct: 147 --YRKNGAVRCI-CNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSGNSDPNLIFEDC 202
Query: 1158 DNLSGLCF-CQDHTEGAHCQLCSPGYYGDPRAGGSC-FRECGG 1198
D ++G C C +T G C+ C+PGYYGD R +C CGG
Sbjct: 203 DEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG 245
Score = 71.2 bits (173), Expect = 1e-11
Identities = 60/228 (26%), Positives = 86/228 (37%), Gaps = 56/228 (24%)
Query: 2172 RCHFGF---VGRNCSTECRCNRHS-ECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAV 2227
+C+ GF + C C CN +S EC + +C+ C+ +T G HCE+CL ++G ++
Sbjct: 66 KCNAGFFHTLSGEC-VPCDCNGNSNEC--LDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122
Query: 2228 GGGT--CRPC------------HAFCRGNSHICISRKELQMSK---------GEP----- 2259
G C+PC + + + CI + G P
Sbjct: 123 RGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGS 182
Query: 2260 --KKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF---LLDGKCTKCQ 2314
KK N + E E C NC N+ G KCE C GY+ + C C
Sbjct: 183 TCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCN 242
Query: 2315 CNGHADTCNEQDGTGCPCQNNTETGTC--QGSSPSDRRDCYKYQCAKC 2360
C G PC ++ TG C +G P DC C KC
Sbjct: 243 CGGG------------PC--DSVTGECLEEGFEPPTGMDCPTISCDKC 276
Score = 42.0 bits (97), Expect = 0.008
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 17/76 (22%)
Query: 2297 ESCLQGYF-LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKY 2355
E C G+F L G+C C CNG+++ C + G CQ NT TG
Sbjct: 65 EKCNAGFFHTLSGECVPCDCNGNSNECLDGSGYCVHCQRNT-TGE--------------- 108
Query: 2356 QCAKCRESFHGSPLGG 2371
C KC + + G + G
Sbjct: 109 HCEKCLDGYIGDSIRG 124
Score = 38.1 bits (87), Expect = 0.12
Identities = 69/278 (24%), Positives = 89/278 (32%), Gaps = 63/278 (22%)
Query: 1918 VFWAGNCSEAACGAADCEQCTREGKCMWTRQFK-RTGETRRILSVQPTYDWTC---FSHS 1973
+ W+ CS AA G + EG RQ T E R L P C F H+
Sbjct: 15 LLWSAACSRAASGDDNAFPFDIEGSSAVGRQDPPETSEPRVALGRLPPAAEKCNAGFFHT 74
Query: 1974 LLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPL 2033
L PC N CLD G HC +++ + C
Sbjct: 75 LSGEC-------------VPCDCNGNSNECLDGSGY---CVHCQRNTTGEHC-------E 111
Query: 2034 RCMAGGCGRLLRG-PESCSLGCAQATQCAL---------CLRRPHCGWCAWGGQDGG--- 2080
+C+ G G +RG P+ C Q C L C R+ C G
Sbjct: 112 KCLDGYIGDSIRGAPQFC-----QPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNC 166
Query: 2081 GRCMEGGLSGP-RDGLTCGRPGASWAFLSCPPEDECANGHHDCNET----QNCHDQPHGY 2135
RC G P G TC + C + DC+E +NC G+
Sbjct: 167 ERCAPGYYGNPLLIGSTCKK-------CDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGF 219
Query: 2136 ECS-CKTGYTMDNMTGLCRPVCAQG-----CVNGSCVE 2167
+C C GY D VC G V G C+E
Sbjct: 220 KCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLE 257
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 85.1 bits (209), Expect = 9e-16
Identities = 102/433 (23%), Positives = 141/433 (32%), Gaps = 63/433 (14%)
Query: 1033 CHCQRGYQGDGISHC---NRTCLEDCGHGVCSGPPDF----TCVCDLGWTSDLPPPTPAP 1085
C C GY G C +R G+C F +C G + T P
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 1086 ----------GPPAPRCSRDC---GCSFHSHCRKRGPG---------FCDECQDWTWGEH 1123
G P S DC C + P CD C G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 1124 CERCRPGSFGNATGSRG-CRPCQCNGHGD-PRRGHCDNLSGLCF-CQDHTEGAHCQLCSP 1180
CERC G FG + G C+PCQCN + D G CD+LSG C C+ T G +C+LC+
Sbjct: 844 CERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCAD 903
Query: 1181 GYYGDPRAGGSCFR-ECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVV 1239
GY+GD +C C + V G A G C
Sbjct: 904 GYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC--------RANVQGQRCDKCKAGT 955
Query: 1240 SATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVL-------AFDGFPRFLDTGVVQSD 1292
+ + C P + +F + S C + G+ F + G +
Sbjct: 956 FGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACE 1015
Query: 1293 RSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGS----C 1348
S + C + R + G N +WG + + G C GS C
Sbjct: 1016 CSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN---TWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1349 PV-PQECVPQDGAAGAGLCRCPQG-WAGPHCRMALC------PENCNAHTGAGTCNQSLG 1400
V +C +GA C +G W P C + C C++ T +C+ G
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTG 1132
Query: 1401 VCICAEGFGGPDC 1413
C C G C
Sbjct: 1133 QCTCKVNVEGIHC 1145
Score = 81.6 bits (200), Expect = 1e-14
Identities = 70/290 (24%), Positives = 115/290 (39%), Gaps = 47/290 (16%)
Query: 2137 CSCKTGYTMDNMTGLCRPVCAQGCVNGSC----VEPDHCRCHFGFVGR------NCSTEC 2186
C+C +N + C + G + C P RC G+ G+ +C C
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQP-C 865
Query: 2187 RCNRHSECAGVGARDH----CLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHA----- 2237
+CN + + + G+ D CL+C+ T G +CE C + G AV C+PC
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925
Query: 2238 ---FCRGNSHICISRKELQMSKGEPKK---YSLD------PEEIENWVTEGPSEDEAVCV 2285
C + C R +Q + + K + L P ++ ++ +E+
Sbjct: 926 FSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC 985
Query: 2286 NCQNNSYGEKCESCLQGYF-LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGS 2344
CQ G+KC+ C GYF +G CT C+C+ + C+ + G C C NT C
Sbjct: 986 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR-CICPPNTIGEKCSKC 1044
Query: 2345 SPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
+P+ C C C + S++ +C ++ T Q NC
Sbjct: 1045 APNTWGHSITTGCKAC------------NCSTVGSLDFQCNVN-TGQCNC 1081
Score = 72.8 bits (177), Expect = 4e-12
Identities = 68/273 (24%), Positives = 96/273 (35%), Gaps = 53/273 (19%)
Query: 2156 CAQGCVNGSCVE--PDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGS 2213
C G SC P H R + G C C+C H+E CL C++HT G
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEP-CQCFGHAESCD-DVTGECLNCKDHTGGP 783
Query: 2214 HCEQCLPLFVGSAVGGGT--CRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIEN 2271
+C++CLP F G G + C+PC S+ L S G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLG-------------- 829
Query: 2272 WVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF----LLDGKCTKCQCNGHAD-----TC 2322
+C C G +CE C +GYF + G C CQCN + D +C
Sbjct: 830 ----------LICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSC 879
Query: 2323 NEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQ-CAKCRESFHGSPLGGQQCYRLISVE 2381
+ G+ C+ T C+ + D + C CR + GS
Sbjct: 880 DSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS-------------F 926
Query: 2382 QECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQ 2414
E C T Q C + + + FG+Q
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Score = 67.8 bits (164), Expect = 1e-10
Identities = 54/170 (31%), Positives = 66/170 (38%), Gaps = 36/170 (21%)
Query: 1056 GHGVCSGPPDFT---CVCDLGWT-----SDLP--------PPTPAPGPPAPRCSRDCGCS 1099
G G PP C C LG++ + LP P PGP C C C+
Sbjct: 1365 GRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCV-PCQCN 1423
Query: 1100 FHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATG-SRGCRPCQCNGHGDPRRGHCD 1158
HS C CQ T G+ CERC G +G G C+ C C P +
Sbjct: 1424 GHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC-----PLISSSN 1478
Query: 1159 NLSGLCF-----------CQDHTEGAHCQLCSPGYYGDP-RAGGSCFREC 1196
N S C C EG +C+ C+PGY G P GGSC +EC
Sbjct: 1479 NFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSC-QEC 1527
Score = 65.1 bits (157), Expect = 9e-10
Identities = 45/144 (31%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 1059 VCSGPPDFT-CVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQD 1117
VC PP +T C+ W P G C C H+ G C C+D
Sbjct: 723 VCQCPPGYTGSSCESCW----PRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKD 778
Query: 1118 WTWGEHCERCRPGSFGNAT--GSRGCRPCQC----NGHGDPRRGHCDNLSGLCF--CQDH 1169
T G +C++C PG +G T S C+PC C + H D GL C
Sbjct: 779 HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG 838
Query: 1170 TEGAHCQLCSPGYYGDPRA-GGSC 1192
G C+ C+ GY+G P GGSC
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSC 862
Score = 55.8 bits (133), Expect = 6e-07
Identities = 80/321 (24%), Positives = 105/321 (32%), Gaps = 92/321 (28%)
Query: 840 CHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPL-C----SQRLTCEDCLA 894
CH+ T C + R C + G L+S C P C S+ CE+
Sbjct: 930 CHSQTGQCECRANVQGQR-----CDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE--- 981
Query: 895 NSSQCAWCQSTHT---CFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQS 951
S QC WCQ T C A + GGC +C
Sbjct: 982 -SGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCT-------------AC------------ 1014
Query: 952 HECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDEC 1011
EC GN +P GRC+ G CS P W ++ C
Sbjct: 1015 -ECSHLGNNCDPKTGRCI---CPPNTIGEKCS----------KCAPNTWGHSITTGCKAC 1060
Query: 1012 RLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCD 1071
+NT +C+C + G + C+R G + P C C
Sbjct: 1061 NCSTVGSLDFQCNVNTG---QCNCHPKFSGAKCTECSR--------GHWNYPRCNLCDCF 1109
Query: 1072 LGWTSDLPPPTPAPGPPAPRC---SRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCR 1128
L PG A C ++ C CS + G C C+ G HC+RCR
Sbjct: 1110 L------------PGTDATTCDSETKKCSCSDQT-------GQC-TCKVNVEGIHCDRCR 1149
Query: 1129 PGSFG-NATGSRGCRPCQCNG 1148
PG FG +A GC C C G
Sbjct: 1150 PGKFGLDAKNPLGCSSCYCFG 1170
Score = 55.5 bits (132), Expect = 7e-07
Identities = 63/243 (25%), Positives = 82/243 (33%), Gaps = 45/243 (18%)
Query: 1021 RATCLNTP--LSYECHCQRGYQGDGISHC--NRTCLEDCGHGVCSGPPDFTCV-CDLGWT 1075
R T + P L +C C GY G C L G GP TCV C
Sbjct: 1366 RGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 1076 SDLPPPTPA---------PGPPAPRCS--------------RDCGCSFHSHCRKRGPGF- 1111
S L P + G RC+ + C C S P
Sbjct: 1426 SSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV 1485
Query: 1112 --------CDECQDWTWGEHCERCRPG---SFGNATGSRGCRPCQCNGHGDPRRGHCDNL 1160
C C G++CERC PG S GN GS C+ C+C+ +G CD +
Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGS--CQECECDPYGS-LPVPCDPV 1542
Query: 1161 SGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL--LTNVSSVALGSRRVGGL 1218
+G C C+ G C C + + C EC G L L + + + G L
Sbjct: 1543 TGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPL 1602
Query: 1219 LPP 1221
P
Sbjct: 1603 PAP 1605
Score = 53.9 bits (128), Expect = 2e-06
Identities = 92/394 (23%), Positives = 129/394 (32%), Gaps = 99/394 (25%)
Query: 2019 SSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWG--G 2076
S Q C P +P + C S L C C + P C CA G G
Sbjct: 801 SEDCQPCACPLNIPSNNFSPTCHL----DRSLGLIC---DGCPVGYTGPRCERCAEGYFG 853
Query: 2077 QDG--GGRCMEGGLSGPRDGLTCGRPGA----SWAFLSCPPE------DECANGHHD--- 2121
Q GG C + D L PG+ S + L C P + CA+G+
Sbjct: 854 QPSVPGGSCQPCQCN---DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV 910
Query: 2122 ---------CNE----TQNCHDQPHGYEC----------SCKTG-YTMDNMTGLCRPVCA 2157
CN ++ CH Q EC CK G + + + G C
Sbjct: 911 DAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCN 970
Query: 2158 Q-GCVNGSCVEPDHCRCHFGFVGRNCS--------------TECRCNR-HSECAGVGARD 2201
G + C E C C G G+ C T C C+ + C R
Sbjct: 971 SFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR- 1029
Query: 2202 HCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAF--------CRGNSHIC------I 2247
+C +T G C +C P G ++ G C+ C+ C N+ C
Sbjct: 1030 --CICPPNTIGEKCSKCAPNTWGHSITTG-CKACNCSTVGSLDFQCNVNTGQCNCHPKFS 1086
Query: 2248 SRKELQMSKGE---PKKY-------SLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCE 2297
K + S+G P+ D ++ + D+ C+ N G C+
Sbjct: 1087 GAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD 1146
Query: 2298 SCLQGYFLLDGK----CTKCQCNGHADTCNEQDG 2327
C G F LD K C+ C C G C+E G
Sbjct: 1147 RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180
Score = 53.1 bits (126), Expect = 4e-06
Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 20/109 (18%)
Query: 1087 PPAPRCSRDCGC----SFHSHCRK------RG--PGFCDECQDWTWGEHCERCRPGSFGN 1134
P PR + C C S + C K RG PG C C+ G C+RC G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGY--- 460
Query: 1135 ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
TG C+ C C+G G C G C C+++ EG C C G++
Sbjct: 461 -TGYPDCKACNCSGLGSKNEDPC---FGPCICKENVEGGDCSRCKSGFF 505
Score = 49.3 bits (116), Expect = 5e-05
Identities = 46/202 (22%), Positives = 68/202 (33%), Gaps = 44/202 (21%)
Query: 2206 CRNHTKGSHCEQCLPLFVGSAVGGGT------CRPCHAFCRGNSHIC-----ISRKELQM 2254
C ++T G C+QC P F GT C C+ C G + C ++R+ L +
Sbjct: 309 CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN--CHGKAEECYYDENVARRNLSL 366
Query: 2255 SKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG------ 2308
+ G VC+NC N+ G CE+C G+F G
Sbjct: 367 N------------------IRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYP 408
Query: 2309 -KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGS 2367
C C C D + + + G GS + C +C + G
Sbjct: 409 RPCQPCHC----DPIGSLNEVCVKDEKHARRGLAPGSCHC-KTGFGGVSCDRCARGYTGY 463
Query: 2368 P-LGGQQCYRLISVEQECCLDP 2388
P C L S ++ C P
Sbjct: 464 PDCKACNCSGLGSKNEDPCFGP 485
Score = 49.3 bits (116), Expect = 5e-05
Identities = 47/193 (24%), Positives = 69/193 (35%), Gaps = 36/193 (18%)
Query: 2186 CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVG-GGTCRPCHAFCRGNSH 2244
C+CN HS C C++HT G CE+C + G G C+ C +S+
Sbjct: 1420 CQCNGHSSLCDPET-SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN 1478
Query: 2245 ICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF 2304
+ P + V EG D+ C C G+ CE C GY
Sbjct: 1479 ------------------NFSP----SCVAEG--LDDYRCTACPRGYEGQYCERCAPGYT 1514
Query: 2305 ----LLDGKCTKCQCNGHAD---TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQC 2357
G C +C+C+ + C+ G C C+ C G R+ ++C
Sbjct: 1515 GSPGNPGGSCQECECDPYGSLPVPCDPVTGF-CTCRPGATGRKCDGCKHWHARE--GWEC 1571
Query: 2358 AKCRESFHGSPLG 2370
C + G LG
Sbjct: 1572 VFCGDECTGLLLG 1584
Score = 48.5 bits (114), Expect = 9e-05
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 19/134 (14%)
Query: 2254 MSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLD------ 2307
M + + S++ E T P D +C G CE+CL G++ L
Sbjct: 1349 MRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGR 1408
Query: 2308 ------GKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQ-------GSSPSDRRDCYK 2354
G C CQCNGH+ C+ + CQ++T C+ G DC +
Sbjct: 1409 TPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQ 1468
Query: 2355 YQCAKCRESFHGSP 2368
C S + SP
Sbjct: 1469 CACPLISSSNNFSP 1482
Score = 46.6 bits (109), Expect = 3e-04
Identities = 29/91 (31%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 1108 GPGFCDECQDWTWGEHCERCRPGSFGNATGS----RGCRPCQCNGHG--------DPRRG 1155
G G C C T G +CE C G F S R C+PC C+ G D +
Sbjct: 374 GGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHA 433
Query: 1156 HCDNLSGLCFCQDHTEGAHCQLCSPGYYGDP 1186
G C C+ G C C+ GY G P
Sbjct: 434 RRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Score = 46.6 bits (109), Expect = 3e-04
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 21/114 (18%)
Query: 2263 SLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGK-----CTKCQCNG 2317
S++ E ++ T+G C G CESC + ++G C CQC G
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFG 761
Query: 2318 HADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGG 2371
HA++C++ G C+++T P C KC F+G P G
Sbjct: 762 HAESCDDVTGECLNCKDHT-------GGP---------YCDKCLPGFYGEPTKG 799
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/346 (21%), Positives = 104/346 (30%), Gaps = 100/346 (28%)
Query: 931 HSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLG----GGNCSLWV 986
++ PRC C + C C DN DFS P G+C +
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNL--------DFSIPGSCDSLSGSCLICK 890
Query: 987 GEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSY--ECHCQRGYQGDGI 1044
G L A + D C+ RC+ + S +C C+ QG
Sbjct: 891 PGTTGRYCELCADGYFGDAVDAKNCQP--CRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 1045 SHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPA-----PGPPAPRCSR----- 1094
C G+ S C C+ + PG +C R
Sbjct: 949 DKCKAGTF-----GLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGY 1003
Query: 1095 ---------DCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC- 1144
C CS + G C C T GE C +C P ++G++ + GC+ C
Sbjct: 1004 FNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSI-TTGCKACN 1061
Query: 1145 ----------------QCNGHG--------DPRRGH------------------------ 1156
QCN H + RGH
Sbjct: 1062 CSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSE 1121
Query: 1157 -----CDNLSGLCFCQDHTEGAHCQLCSPGYYG----DPRAGGSCF 1193
C + +G C C+ + EG HC C PG +G +P SC+
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Score = 40.4 bits (93), Expect = 0.025
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 23/88 (26%)
Query: 137 FRFSLCPGGCQSHGQCQPPGVCACEPGW----GGPDCGLQECSAYCGSHGTCASPLGP-- 190
+R + CP G + C+ C PG+ G P QEC C +G+ P P
Sbjct: 1492 YRCTACPRGYEGQ-YCE-----RCAPGYTGSPGNPGGSCQECE--CDPYGSLPVPCDPVT 1543
Query: 191 --CRCEPGFLGRACDLHLWENQGAGWWH 216
C C PG GR CD G WH
Sbjct: 1544 GFCTCRPGATGRKCD-------GCKHWH 1564
Score = 39.7 bits (91), Expect = 0.042
Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 21/91 (23%)
Query: 1114 ECQDWTWGEHCERCRPG------SFGNATGSRGCRPCQCNGHGD--------PRRGHCDN 1159
EC+ T G+ C++C PG G C C C+G + RR N
Sbjct: 308 ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLN 367
Query: 1160 L------SGLCF-CQDHTEGAHCQLCSPGYY 1183
+ G+C C +T G +C+ C+ G++
Sbjct: 368 IRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Score = 37.7 bits (86), Expect = 0.16
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 1351 PQECVPQDGAAGAGLCRCPQGWAG-PHCRMALCPENCNAHTGAGTCNQS--LGVCICAEG 1407
P C + G G RC +G+ G P C+ C +G G+ N+ G CIC E
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC-------SGLGSKNEDPCFGPCICKEN 491
Query: 1408 FGGPDCA 1414
G DC+
Sbjct: 492 VEGGDCS 498
Score = 37.4 bits (85), Expect = 0.21
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 18/81 (22%)
Query: 1356 PQDG--AAGAGLCRCPQGWAGPHCRM--------------ALCPENCNAHTGAGTCNQSL 1399
P DG AA +C+CP G+ G C +C E C A +C+
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVT 770
Query: 1400 GVCI-CAEGFGGPDCATKLDG 1419
G C+ C + GGP C L G
Sbjct: 771 GECLNCKDHTGGPYCDKCLPG 791
Score = 36.6 bits (83), Expect = 0.35
Identities = 25/76 (32%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 143 PGGCQSHGQ----CQPPGVCACEPGWGGPDC--------GLQE--CSAYCGSH--GTCAS 186
P C S G C+ G C C+PG G C QE C+A SH C
Sbjct: 966 PCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 187 PLGPCRCEPGFLGRAC 202
G C C P +G C
Sbjct: 1026 KTGRCICPPNTIGEKC 1041
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 85.1 bits (209), Expect = 9e-16
Identities = 102/433 (23%), Positives = 141/433 (32%), Gaps = 63/433 (14%)
Query: 1033 CHCQRGYQGDGISHC---NRTCLEDCGHGVCSGPPDF----TCVCDLGWTSDLPPPTPAP 1085
C C GY G C +R G+C F +C G + T P
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 1086 ----------GPPAPRCSRDC---GCSFHSHCRKRGPG---------FCDECQDWTWGEH 1123
G P S DC C + P CD C G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPR 843
Query: 1124 CERCRPGSFGNATGSRG-CRPCQCNGHGD-PRRGHCDNLSGLCF-CQDHTEGAHCQLCSP 1180
CERC G FG + G C+PCQCN + D G CD+LSG C C+ T G +C+LC+
Sbjct: 844 CERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCAD 903
Query: 1181 GYYGDPRAGGSCFR-ECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVV 1239
GY+GD +C C + V G A G C
Sbjct: 904 GYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC--------RANVQGQRCDKCKAGT 955
Query: 1240 SATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVL-------AFDGFPRFLDTGVVQSD 1292
+ + C P + +F + S C + G+ F + G +
Sbjct: 956 FGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACE 1015
Query: 1293 RSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGS----C 1348
S + C + R + G N +WG + + G C GS C
Sbjct: 1016 CSHLGNNCDPKTGRCICPPNTIGEKCSKCAPN---TWGHSITTGCKACNCSTVGSLDFQC 1072
Query: 1349 PV-PQECVPQDGAAGAGLCRCPQG-WAGPHCRMALC------PENCNAHTGAGTCNQSLG 1400
V +C +GA C +G W P C + C C++ T +C+ G
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTG 1132
Query: 1401 VCICAEGFGGPDC 1413
C C G C
Sbjct: 1133 QCTCKVNVEGIHC 1145
Score = 81.6 bits (200), Expect = 1e-14
Identities = 70/290 (24%), Positives = 115/290 (39%), Gaps = 47/290 (16%)
Query: 2137 CSCKTGYTMDNMTGLCRPVCAQGCVNGSC----VEPDHCRCHFGFVGR------NCSTEC 2186
C+C +N + C + G + C P RC G+ G+ +C C
Sbjct: 807 CACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQP-C 865
Query: 2187 RCNRHSECAGVGARDH----CLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHA----- 2237
+CN + + + G+ D CL+C+ T G +CE C + G AV C+PC
Sbjct: 866 QCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS 925
Query: 2238 ---FCRGNSHICISRKELQMSKGEPKK---YSLD------PEEIENWVTEGPSEDEAVCV 2285
C + C R +Q + + K + L P ++ ++ +E+
Sbjct: 926 FSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC 985
Query: 2286 NCQNNSYGEKCESCLQGYF-LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGS 2344
CQ G+KC+ C GYF +G CT C+C+ + C+ + G C C NT C
Sbjct: 986 WCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR-CICPPNTIGEKCSKC 1044
Query: 2345 SPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
+P+ C C C + S++ +C ++ T Q NC
Sbjct: 1045 APNTWGHSITTGCKAC------------NCSTVGSLDFQCNVN-TGQCNC 1081
Score = 72.8 bits (177), Expect = 4e-12
Identities = 68/273 (24%), Positives = 96/273 (35%), Gaps = 53/273 (19%)
Query: 2156 CAQGCVNGSCVE--PDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGS 2213
C G SC P H R + G C C+C H+E CL C++HT G
Sbjct: 726 CPPGYTGSSCESCWPRHRRVNGTIFGGICEP-CQCFGHAESCD-DVTGECLNCKDHTGGP 783
Query: 2214 HCEQCLPLFVGSAVGGGT--CRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIEN 2271
+C++CLP F G G + C+PC S+ L S G
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLG-------------- 829
Query: 2272 WVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF----LLDGKCTKCQCNGHAD-----TC 2322
+C C G +CE C +GYF + G C CQCN + D +C
Sbjct: 830 ----------LICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSC 879
Query: 2323 NEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQ-CAKCRESFHGSPLGGQQCYRLISVE 2381
+ G+ C+ T C+ + D + C CR + GS
Sbjct: 880 DSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGS-------------F 926
Query: 2382 QECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQ 2414
E C T Q C + + + FG+Q
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQ 959
Score = 67.8 bits (164), Expect = 1e-10
Identities = 54/170 (31%), Positives = 66/170 (38%), Gaps = 36/170 (21%)
Query: 1056 GHGVCSGPPDFT---CVCDLGWT-----SDLP--------PPTPAPGPPAPRCSRDCGCS 1099
G G PP C C LG++ + LP P PGP C C C+
Sbjct: 1365 GRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCV-PCQCN 1423
Query: 1100 FHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATG-SRGCRPCQCNGHGDPRRGHCD 1158
HS C CQ T G+ CERC G +G G C+ C C P +
Sbjct: 1424 GHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC-----PLISSSN 1478
Query: 1159 NLSGLCF-----------CQDHTEGAHCQLCSPGYYGDP-RAGGSCFREC 1196
N S C C EG +C+ C+PGY G P GGSC +EC
Sbjct: 1479 NFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSC-QEC 1527
Score = 65.1 bits (157), Expect = 9e-10
Identities = 45/144 (31%), Positives = 58/144 (40%), Gaps = 14/144 (9%)
Query: 1059 VCSGPPDFT-CVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQD 1117
VC PP +T C+ W P G C C H+ G C C+D
Sbjct: 723 VCQCPPGYTGSSCESCW----PRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKD 778
Query: 1118 WTWGEHCERCRPGSFGNAT--GSRGCRPCQC----NGHGDPRRGHCDNLSGLCF--CQDH 1169
T G +C++C PG +G T S C+PC C + H D GL C
Sbjct: 779 HTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG 838
Query: 1170 TEGAHCQLCSPGYYGDPRA-GGSC 1192
G C+ C+ GY+G P GGSC
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSC 862
Score = 55.8 bits (133), Expect = 6e-07
Identities = 80/321 (24%), Positives = 105/321 (32%), Gaps = 92/321 (28%)
Query: 840 CHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEECPPL-C----SQRLTCEDCLA 894
CH+ T C + R C + G L+S C P C S+ CE+
Sbjct: 930 CHSQTGQCECRANVQGQR-----CDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE--- 981
Query: 895 NSSQCAWCQSTHT---CFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQS 951
S QC WCQ T C A + GGC +C
Sbjct: 982 -SGQC-WCQPGVTGKKCDRCAHGYFNFQEGGCT-------------AC------------ 1014
Query: 952 HECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDEC 1011
EC GN +P GRC+ G CS P W ++ C
Sbjct: 1015 -ECSHLGNNCDPKTGRCI---CPPNTIGEKCS----------KCAPNTWGHSITTGCKAC 1060
Query: 1012 RLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCD 1071
+NT +C+C + G + C+R G + P C C
Sbjct: 1061 NCSTVGSLDFQCNVNTG---QCNCHPKFSGAKCTECSR--------GHWNYPRCNLCDCF 1109
Query: 1072 LGWTSDLPPPTPAPGPPAPRC---SRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCR 1128
L PG A C ++ C CS + G C C+ G HC+RCR
Sbjct: 1110 L------------PGTDATTCDSETKKCSCSDQT-------GQC-TCKVNVEGIHCDRCR 1149
Query: 1129 PGSFG-NATGSRGCRPCQCNG 1148
PG FG +A GC C C G
Sbjct: 1150 PGKFGLDAKNPLGCSSCYCFG 1170
Score = 55.5 bits (132), Expect = 7e-07
Identities = 63/243 (25%), Positives = 82/243 (33%), Gaps = 45/243 (18%)
Query: 1021 RATCLNTP--LSYECHCQRGYQGDGISHC--NRTCLEDCGHGVCSGPPDFTCV-CDLGWT 1075
R T + P L +C C GY G C L G GP TCV C
Sbjct: 1366 RGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH 1425
Query: 1076 SDLPPPTPA---------PGPPAPRCS--------------RDCGCSFHSHCRKRGPGF- 1111
S L P + G RC+ + C C S P
Sbjct: 1426 SSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV 1485
Query: 1112 --------CDECQDWTWGEHCERCRPG---SFGNATGSRGCRPCQCNGHGDPRRGHCDNL 1160
C C G++CERC PG S GN GS C+ C+C+ +G CD +
Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGS--CQECECDPYGS-LPVPCDPV 1542
Query: 1161 SGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRAL--LTNVSSVALGSRRVGGL 1218
+G C C+ G C C + + C EC G L L + + + G L
Sbjct: 1543 TGFCTCRPGATGRKCDGCKHWHAREGWECVFCGDECTGLLLGDLARLEQMVMSINLTGPL 1602
Query: 1219 LPP 1221
P
Sbjct: 1603 PAP 1605
Score = 53.9 bits (128), Expect = 2e-06
Identities = 92/394 (23%), Positives = 129/394 (32%), Gaps = 99/394 (25%)
Query: 2019 SSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWG--G 2076
S Q C P +P + C S L C C + P C CA G G
Sbjct: 801 SEDCQPCACPLNIPSNNFSPTCHL----DRSLGLIC---DGCPVGYTGPRCERCAEGYFG 853
Query: 2077 QDG--GGRCMEGGLSGPRDGLTCGRPGA----SWAFLSCPPE------DECANGHHD--- 2121
Q GG C + D L PG+ S + L C P + CA+G+
Sbjct: 854 QPSVPGGSCQPCQCN---DNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV 910
Query: 2122 ---------CNE----TQNCHDQPHGYEC----------SCKTG-YTMDNMTGLCRPVCA 2157
CN ++ CH Q EC CK G + + + G C
Sbjct: 911 DAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCN 970
Query: 2158 Q-GCVNGSCVEPDHCRCHFGFVGRNCS--------------TECRCNR-HSECAGVGARD 2201
G + C E C C G G+ C T C C+ + C R
Sbjct: 971 SFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGR- 1029
Query: 2202 HCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAF--------CRGNSHIC------I 2247
+C +T G C +C P G ++ G C+ C+ C N+ C
Sbjct: 1030 --CICPPNTIGEKCSKCAPNTWGHSITTG-CKACNCSTVGSLDFQCNVNTGQCNCHPKFS 1086
Query: 2248 SRKELQMSKGE---PKKY-------SLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCE 2297
K + S+G P+ D ++ + D+ C+ N G C+
Sbjct: 1087 GAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD 1146
Query: 2298 SCLQGYFLLDGK----CTKCQCNGHADTCNEQDG 2327
C G F LD K C+ C C G C+E G
Sbjct: 1147 RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180
Score = 53.1 bits (126), Expect = 4e-06
Identities = 35/109 (32%), Positives = 46/109 (42%), Gaps = 20/109 (18%)
Query: 1087 PPAPRCSRDCGC----SFHSHCRK------RG--PGFCDECQDWTWGEHCERCRPGSFGN 1134
P PR + C C S + C K RG PG C C+ G C+RC G
Sbjct: 405 PNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSC-HCKTGFGGVSCDRCARGY--- 460
Query: 1135 ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
TG C+ C C+G G C G C C+++ EG C C G++
Sbjct: 461 -TGYPDCKACNCSGLGSKNEDPC---FGPCICKENVEGGDCSRCKSGFF 505
Score = 49.3 bits (116), Expect = 5e-05
Identities = 46/202 (22%), Positives = 68/202 (33%), Gaps = 44/202 (21%)
Query: 2206 CRNHTKGSHCEQCLPLFVGSAVGGGT------CRPCHAFCRGNSHIC-----ISRKELQM 2254
C ++T G C+QC P F GT C C+ C G + C ++R+ L +
Sbjct: 309 CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN--CHGKAEECYYDENVARRNLSL 366
Query: 2255 SKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDG------ 2308
+ G VC+NC N+ G CE+C G+F G
Sbjct: 367 N------------------IRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYP 408
Query: 2309 -KCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGS 2367
C C C D + + + G GS + C +C + G
Sbjct: 409 RPCQPCHC----DPIGSLNEVCVKDEKHARRGLAPGSCHC-KTGFGGVSCDRCARGYTGY 463
Query: 2368 P-LGGQQCYRLISVEQECCLDP 2388
P C L S ++ C P
Sbjct: 464 PDCKACNCSGLGSKNEDPCFGP 485
Score = 49.3 bits (116), Expect = 5e-05
Identities = 47/193 (24%), Positives = 69/193 (35%), Gaps = 36/193 (18%)
Query: 2186 CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVG-GGTCRPCHAFCRGNSH 2244
C+CN HS C C++HT G CE+C + G G C+ C +S+
Sbjct: 1420 CQCNGHSSLCDPET-SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN 1478
Query: 2245 ICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF 2304
+ P + V EG D+ C C G+ CE C GY
Sbjct: 1479 ------------------NFSP----SCVAEG--LDDYRCTACPRGYEGQYCERCAPGYT 1514
Query: 2305 ----LLDGKCTKCQCNGHAD---TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQC 2357
G C +C+C+ + C+ G C C+ C G R+ ++C
Sbjct: 1515 GSPGNPGGSCQECECDPYGSLPVPCDPVTGF-CTCRPGATGRKCDGCKHWHARE--GWEC 1571
Query: 2358 AKCRESFHGSPLG 2370
C + G LG
Sbjct: 1572 VFCGDECTGLLLG 1584
Score = 48.5 bits (114), Expect = 9e-05
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 19/134 (14%)
Query: 2254 MSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLD------ 2307
M + + S++ E T P D +C G CE+CL G++ L
Sbjct: 1349 MRQSRISEISMEVAEQGRGTTMTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGR 1408
Query: 2308 ------GKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQ-------GSSPSDRRDCYK 2354
G C CQCNGH+ C+ + CQ++T C+ G DC +
Sbjct: 1409 TPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQ 1468
Query: 2355 YQCAKCRESFHGSP 2368
C S + SP
Sbjct: 1469 CACPLISSSNNFSP 1482
Score = 46.6 bits (109), Expect = 3e-04
Identities = 29/91 (31%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 1108 GPGFCDECQDWTWGEHCERCRPGSFGNATGS----RGCRPCQCNGHG--------DPRRG 1155
G G C C T G +CE C G F S R C+PC C+ G D +
Sbjct: 374 GGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHA 433
Query: 1156 HCDNLSGLCFCQDHTEGAHCQLCSPGYYGDP 1186
G C C+ G C C+ GY G P
Sbjct: 434 RRGLAPGSCHCKTGFGGVSCDRCARGYTGYP 464
Score = 46.6 bits (109), Expect = 3e-04
Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 21/114 (18%)
Query: 2263 SLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGK-----CTKCQCNG 2317
S++ E ++ T+G C G CESC + ++G C CQC G
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFG 761
Query: 2318 HADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGG 2371
HA++C++ G C+++T P C KC F+G P G
Sbjct: 762 HAESCDDVTGECLNCKDHT-------GGP---------YCDKCLPGFYGEPTKG 799
Score = 45.4 bits (106), Expect = 8e-04
Identities = 73/346 (21%), Positives = 104/346 (30%), Gaps = 100/346 (28%)
Query: 931 HSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLG----GGNCSLWV 986
++ PRC C + C C DN DFS P G+C +
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNL--------DFSIPGSCDSLSGSCLICK 890
Query: 987 GEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSY--ECHCQRGYQGDGI 1044
G L A + D C+ RC+ + S +C C+ QG
Sbjct: 891 PGTTGRYCELCADGYFGDAVDAKNCQP--CRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 1045 SHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPA-----PGPPAPRCSR----- 1094
C G+ S C C+ + PG +C R
Sbjct: 949 DKCKAGTF-----GLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGY 1003
Query: 1095 ---------DCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC- 1144
C CS + G C C T GE C +C P ++G++ + GC+ C
Sbjct: 1004 FNFQEGGCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSI-TTGCKACN 1061
Query: 1145 ----------------QCNGHG--------DPRRGH------------------------ 1156
QCN H + RGH
Sbjct: 1062 CSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLPGTDATTCDSE 1121
Query: 1157 -----CDNLSGLCFCQDHTEGAHCQLCSPGYYG----DPRAGGSCF 1193
C + +G C C+ + EG HC C PG +G +P SC+
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY 1167
Score = 40.4 bits (93), Expect = 0.025
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 23/88 (26%)
Query: 137 FRFSLCPGGCQSHGQCQPPGVCACEPGW----GGPDCGLQECSAYCGSHGTCASPLGP-- 190
+R + CP G + C+ C PG+ G P QEC C +G+ P P
Sbjct: 1492 YRCTACPRGYEGQ-YCE-----RCAPGYTGSPGNPGGSCQECE--CDPYGSLPVPCDPVT 1543
Query: 191 --CRCEPGFLGRACDLHLWENQGAGWWH 216
C C PG GR CD G WH
Sbjct: 1544 GFCTCRPGATGRKCD-------GCKHWH 1564
Score = 39.7 bits (91), Expect = 0.042
Identities = 24/91 (26%), Positives = 38/91 (41%), Gaps = 21/91 (23%)
Query: 1114 ECQDWTWGEHCERCRPG------SFGNATGSRGCRPCQCNGHGD--------PRRGHCDN 1159
EC+ T G+ C++C PG G C C C+G + RR N
Sbjct: 308 ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLN 367
Query: 1160 L------SGLCF-CQDHTEGAHCQLCSPGYY 1183
+ G+C C +T G +C+ C+ G++
Sbjct: 368 IRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Score = 37.7 bits (86), Expect = 0.16
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 10/67 (14%)
Query: 1351 PQECVPQDGAAGAGLCRCPQGWAG-PHCRMALCPENCNAHTGAGTCNQS--LGVCICAEG 1407
P C + G G RC +G+ G P C+ C +G G+ N+ G CIC E
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNC-------SGLGSKNEDPCFGPCICKEN 491
Query: 1408 FGGPDCA 1414
G DC+
Sbjct: 492 VEGGDCS 498
Score = 37.4 bits (85), Expect = 0.21
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 18/81 (22%)
Query: 1356 PQDG--AAGAGLCRCPQGWAGPHCRM--------------ALCPENCNAHTGAGTCNQSL 1399
P DG AA +C+CP G+ G C +C E C A +C+
Sbjct: 712 PTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVT 770
Query: 1400 GVCI-CAEGFGGPDCATKLDG 1419
G C+ C + GGP C L G
Sbjct: 771 GECLNCKDHTGGPYCDKCLPG 791
Score = 36.6 bits (83), Expect = 0.35
Identities = 25/76 (32%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 143 PGGCQSHGQ----CQPPGVCACEPGWGGPDC--------GLQE--CSAYCGSH--GTCAS 186
P C S G C+ G C C+PG G C QE C+A SH C
Sbjct: 966 PCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 187 PLGPCRCEPGFLGRAC 202
G C C P +G C
Sbjct: 1026 KTGRCICPPNTIGEKC 1041
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 84.0 bits (206), Expect = 2e-15
Identities = 60/197 (30%), Positives = 82/197 (41%), Gaps = 39/197 (19%)
Query: 2186 CRCNRH-SECAGVGARDHCLLCRNHTKGSHCEQCLPLFV------GSAVGGGTCRPCHAF 2238
C+CN H SEC A C+++T G+ CE+CLP F G+A C PC+
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN-- 328
Query: 2239 CRGNSHICISRKELQMSKGEP------KKYSLDP------EEIENWVTEGPSE------- 2279
C G S C +EL S G + ++ P E +W P +
Sbjct: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSA 388
Query: 2280 -------DEAVCVNCQNNSYGEKCESCLQGYF-LLDGKCTKCQCN--GHADTCNEQDGTG 2329
D+ C+ G KC+ CL G+ L +G C C CN G DTC+ + G
Sbjct: 389 GSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGR- 447
Query: 2330 CPCQNNTETGTCQGSSP 2346
CPC+ N E C P
Sbjct: 448 CPCKENVEGNLCDRCRP 464
Score = 83.6 bits (205), Expect = 3e-15
Identities = 102/391 (26%), Positives = 136/391 (34%), Gaps = 83/391 (21%)
Query: 1085 PGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
P P C S H C G C C+ G C+RC PG + G GCRPC
Sbjct: 376 PRMPCQPCDCQSAGSLHLQCDDTGT--C-ACKPTVTGWKCDRCLPGFHSLSEG--GCRPC 430
Query: 1145 QCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYG----DPRAGGSCF-----RE 1195
CN G CD SG C C+++ EG C C PG + +P SCF +
Sbjct: 431 TCNPAGS--LDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKV 488
Query: 1196 CGGRA------LLTNVSSVALG--SRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQP 1247
C A +L++ A G +R VGG P P S ++S +E +
Sbjct: 489 CASTAQFQVHHILSDFHQGAEGWWARSVGGSEHP--------PQWSPNGVLLSPEDEEEL 540
Query: 1248 CAPGTLC--------PPLTLTFS-PDSSTPCTLSYVLAFDGFPRFLDTGVVQS------D 1292
AP PL LTF P +P + L G L +
Sbjct: 541 TAPEKFLGDQRFSYGQPLILTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHP 600
Query: 1293 RSLIAAFCGQRRDRPLT--------VQALSGLLVLHWEANGSSSWGFNASVGSARCGSGG 1344
R + F Q + + L+ L L + S + R S
Sbjct: 601 REVELRFHLQETSEDVAPPLPPFHFQRLLANLTSLRLRVSPGPSPAGPVFLTEVRLTSAR 660
Query: 1345 PGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCR---------------MALC-PENCNA 1388
PG P A+ +C CP G+ G C A C P CN
Sbjct: 661 PGLSP---------PASWVEICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQ 711
Query: 1389 HTGAGTCNQSLGVCICAEGFGGPDCATKLDG 1419
H GTC+ + G+C+C+ GP C L G
Sbjct: 712 H---GTCDPNTGICVCSHHTEGPSCERCLPG 739
Score = 81.6 bits (200), Expect = 1e-14
Identities = 81/302 (26%), Positives = 105/302 (34%), Gaps = 87/302 (28%)
Query: 2137 CSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAG 2196
CSC TGY TG CA G + C C CN+H C
Sbjct: 673 CSCPTGY-----TGQFCESCAPGYKREMPQGGPYASC----------VPCTCNQHGTC-- 715
Query: 2197 VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGG--GTCRPCHAFCRGNSHICISRKELQM 2254
+C +HT+G CE+CLP F G+ G C+PC C G S
Sbjct: 716 -DPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP--CPGQSA---------- 762
Query: 2255 SKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF----LLDG-- 2308
T P E VC +C G +CE C G+F L G
Sbjct: 763 ------------------CTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHP 804
Query: 2309 -KCTKCQCNGHAD-----TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRE 2362
C +CQC+G+ D C+ G C +NT TG C C+E
Sbjct: 805 QPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNT-TGD---------------HCEHCQE 848
Query: 2363 SFHGSPLGGQ--------QCYRLISVEQECCLDP-TSQTNCFHEPKRRALGPGRTVLFGV 2413
F+GS L + C+ SV ++ DP T Q +C R F +
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDL 908
Query: 2414 QP 2415
QP
Sbjct: 909 QP 910
Score = 72.4 bits (176), Expect = 6e-12
Identities = 72/275 (26%), Positives = 97/275 (35%), Gaps = 81/275 (29%)
Query: 938 SCDGFLTCHE----CLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLP 993
+C+ TC C+ SH + + P+ RCL G + P G
Sbjct: 708 TCNQHGTCDPNTGICVCSH------HTEGPSCERCLPGFYGNPFAG-------------- 747
Query: 994 VALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYEC---HCQRGYQGDGISHCNRT 1050
D+C+ C ++ C P S E HC G +G R
Sbjct: 748 -------------QADDCQP--CPCPGQSACTTIPESREVVCTHCPPGQRG-------RR 785
Query: 1051 CLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRG-- 1108
C VCD G+ D P G P P C CS + G
Sbjct: 786 CE----------------VCDDGFFGD---PLGLFGHPQP--CHQCQCSGNVDPNAVGNC 824
Query: 1109 ---PGFCDECQDWTWGEHCERCRPGSFGNATGSR---GCRPCQCNGHGD-PRRGHCDNLS 1161
G C C T G+HCE C+ G +G+A R C PC C+ G + CD ++
Sbjct: 825 DPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVT 884
Query: 1162 GLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFREC 1196
G C C H C C PG++ D + G C R C
Sbjct: 885 GQCSCLPHVTARDCSRCYPGFF-DLQPGRGC-RSC 917
Score = 68.9 bits (167), Expect = 6e-11
Identities = 32/78 (41%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 1115 CQDWTWGEHCERCRPG---SFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTE 1171
C G+ CE C PG C PC CN HG CD +G+C C HTE
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-----CDPNTGICVCSHHTE 729
Query: 1172 GAHCQLCSPGYYGDPRAG 1189
G C+ C PG+YG+P AG
Sbjct: 730 GPSCERCLPGFYGNPFAG 747
Score = 59.3 bits (142), Expect = 5e-08
Identities = 36/107 (33%), Positives = 45/107 (42%), Gaps = 17/107 (15%)
Query: 1098 CSFHSHCRKRGPGFCDE----CQDWTWGEHCERC------RPGSFGNATGSRGCRPCQCN 1147
C + H + GP + CQ T G CERC RP + G A + C PC C+
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 1148 GHG-----DPRRGHCDNLSGLC-FCQDHTEGAHCQLCSPGYY-GDPR 1187
G D G C C+DHT G HC+ C +Y DPR
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPR 377
Score = 57.8 bits (138), Expect = 1e-07
Identities = 90/395 (22%), Positives = 129/395 (32%), Gaps = 135/395 (34%)
Query: 2095 LTCGRPG----ASWAFL-SCPPE------DECANGHHDCNETQNCHDQPHG------YEC 2137
LT RPG ASW + SCP + CA G+ + P G C
Sbjct: 656 LTSARPGLSPPASWVEICSCPTGYTGQFCESCAPGYK--------REMPQGGPYASCVPC 707
Query: 2138 SCKTGYTMDNMTGLCRPVCAQGCVNGSCV-------------EPDHCR------------ 2172
+C T D TG+C VC+ SC + D C+
Sbjct: 708 TCNQHGTCDPNTGIC--VCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTT 765
Query: 2173 -----------CHFGFVGRNCST--------------------ECRCNRHSECAGVGARD 2201
C G GR C +C+C+ + + VG D
Sbjct: 766 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCD 825
Query: 2202 ----HCLLCRNHTKGSHCEQCLPLFVGSAVG---GGTCRPCHAFCRGN------------ 2242
HCL C ++T G HCE C F GSA+ C PC +G+
Sbjct: 826 PLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885
Query: 2243 SHICISRKELQ-MSKGEPKKYSLDP-EEIENWVTEGPSEDEAVC------VNCQNNSYGE 2294
C+ + S+ P + L P + E C C+ G+
Sbjct: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQ 945
Query: 2295 KCESCLQGYFLLDGK-CTKCQCN--GHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRD 2351
C+ C G+F K C C+C+ G A ++GT C C+ E
Sbjct: 946 ACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGT-CVCRPGFE-------------- 990
Query: 2352 CYKYQCAKCRESFHGSPLGGQ-----QCYRLISVE 2381
Y+C +C ++F + G CY L+ E
Sbjct: 991 --GYKCDRCHDNFFLTADGTHCQQCPSCYALVKEE 1023
Score = 54.3 bits (129), Expect = 2e-06
Identities = 56/206 (27%), Positives = 79/206 (38%), Gaps = 25/206 (12%)
Query: 1024 CLNTPLSYEC-HCQRGYQGDGIS-HCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPP 1081
CL+ C HCQ G+ G ++ C+ H S C G S LP
Sbjct: 834 CLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHV 893
Query: 1082 TPA------PG----PPAPRCSRDCGC----SFHSHCRKRGPGFCDECQDWTWGEHCERC 1127
T PG P C R C C S C + G C C+ G+ C+RC
Sbjct: 894 TARDCSRCYPGFFDLQPGRGC-RSCKCHPLGSQEDQCHPK-TGQCT-CRPGVTGQACDRC 950
Query: 1128 RPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPR 1187
+ G FG + +GCR C+C+ G C +G C C+ EG C C ++
Sbjct: 951 QLGFFGFSI--KGCRACRCSPLG-AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFF--LT 1004
Query: 1188 AGGSCFRECGGRALLTNVSSVALGSR 1213
A G+ ++C L + L +R
Sbjct: 1005 ADGTHCQQCPSCYALVKEEAAKLKAR 1030
Score = 46.6 bits (109), Expect = 3e-04
Identities = 44/165 (26%), Positives = 59/165 (35%), Gaps = 30/165 (18%)
Query: 2186 CRCN-RHSECA-------GVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHA 2237
C C+ R EC G C CR+HT G HCE+C F C+PC
Sbjct: 327 CNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRM-PCQPCDC 385
Query: 2238 FCRGNSHI-------CISRKELQMSKGE---PKKYSLDPEEIENWVTEGPSEDEAVC--- 2284
G+ H+ C + + K + P +SL T P+ C
Sbjct: 386 QSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRP-CTCNPAGSLDTCDPR 444
Query: 2285 ---VNCQNNSYGEKCESCLQGYFLLD----GKCTKCQCNGHADTC 2322
C+ N G C+ C G F L C+ C C GH+ C
Sbjct: 445 SGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVC 489
Score = 45.4 bits (106), Expect = 8e-04
Identities = 38/132 (28%), Positives = 52/132 (39%), Gaps = 29/132 (21%)
Query: 2277 PSEDEAVCVNCQNNSYGEKCESCLQGY--FLLDG----KCTKCQCNGHADTCNEQDGTGC 2330
P+ +C +C G+ CESC GY + G C C CN H TC+ G C
Sbjct: 666 PASWVEIC-SCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHG-TCDPNTGI-C 722
Query: 2331 PCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQ--QCYRLISVEQECC--L 2386
C ++TE PS C +C F+G+P GQ C Q C +
Sbjct: 723 VCSHHTE-------GPS---------CERCLPGFYGNPFAGQADDCQPCPCPGQSACTTI 766
Query: 2387 DPTSQTNCFHEP 2398
+ + C H P
Sbjct: 767 PESREVVCTHCP 778
Score = 42.7 bits (99), Expect = 0.005
Identities = 59/245 (24%), Positives = 82/245 (33%), Gaps = 41/245 (16%)
Query: 2034 RCMAGG----CGRLLRGPESCSLGC-AQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGL 2088
RC G CG + G +C T C CL A G + C+
Sbjct: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
Query: 2089 SGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECS-CKTGYTMDN 2147
SG + T R F S C HH C D G C C+ + +
Sbjct: 330 SGRSEECTFDRE----LFRSTGHGGRC---HH-------CRDHTAGPHCERCQENFYHWD 375
Query: 2148 MTGLCRPVCAQ--GCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHS---------ECAG 2196
C+P Q G ++ C + C C G C C HS C
Sbjct: 376 PRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCD-RCLPGFHSLSEGGCRPCTCNP 434
Query: 2197 VGARDHC------LLCRNHTKGSHCEQCLP-LFVGSAVGGGTCRPCHAFCRGNSHICISR 2249
G+ D C C+ + +G+ C++C P F C C FC G+S +C S
Sbjct: 435 AGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSC--FCYGHSKVCAST 492
Query: 2250 KELQM 2254
+ Q+
Sbjct: 493 AQFQV 497
Score = 42.4 bits (98), Expect = 0.006
Identities = 89/390 (22%), Positives = 121/390 (31%), Gaps = 95/390 (24%)
Query: 1864 CSECLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQREVFWAGN 1923
C C + R + G AS C CT G C G C + E G
Sbjct: 684 CESCAPGYKREMPQGGPYAS---CVPCTCNQHGTCDPNTGICVCSHHTEGPSCERCLPGF 740
Query: 1924 CSEAACGAAD-CEQCTREGKCMWT-----RQFKRT----GETRRILSV------------ 1961
G AD C+ C G+ T R+ T G+ R V
Sbjct: 741 YGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGL 800
Query: 1962 ----QPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHC- 2016
QP + C NV P V + PL +C CL + D +HC
Sbjct: 801 FGHPQPCHQCQCSG----NVDPNAVGNCDPLS--------GHCLRCLHNTTGDH-CEHCQ 847
Query: 2017 --VWSSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAW 2074
+ S+L + +P C +G S + C T CL C+
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHP-------QGSVSEQMPCDPVTGQCSCLPHVTARDCS- 899
Query: 2075 GGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPP----EDECANGHHDCNETQNCHD 2130
RC G +PG C P ED+C C C
Sbjct: 900 -------RCYPGFFDL--------QPGRGCRSCKCHPLGSQEDQCHPKTGQCT----CRP 940
Query: 2131 QPHGYECS-CKTGYTMDNMTGLCRPVCAQ-GCVNGSCVEPDHCRCHFGFVGRNCSTECRC 2188
G C C+ G+ ++ G C+ G + C E C C GF G C RC
Sbjct: 941 GVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEGYKCD---RC 997
Query: 2189 NRHSECAGVGARDHCLLCRNHTKGSHCEQC 2218
+ D+ L + G+HC+QC
Sbjct: 998 H-----------DNFFLTAD---GTHCQQC 1013
Score = 39.7 bits (91), Expect = 0.042
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 18/79 (22%)
Query: 143 PGGCQSHG----QCQPPGVCACEP---GWGGPDC----------GLQECSAY-CGSHGTC 184
P CQS G QC G CAC+P GW C G + C+ GS TC
Sbjct: 382 PCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTC 441
Query: 185 ASPLGPCRCEPGFLGRACD 203
G C C+ G CD
Sbjct: 442 DPRSGRCPCKENVEGNLCD 460
Score = 39.3 bits (90), Expect = 0.055
Identities = 42/167 (25%), Positives = 66/167 (39%), Gaps = 41/167 (24%)
Query: 2256 KGEPKKYSLDPEE-IENWVTEGPSEDEAVCVNCQNNSYGE---KCESCLQGYFLLDGKCT 2311
+G P Y+ + ++ WVT E + + N++G+ K LQ Y+ +
Sbjct: 211 EGRPSAYNFEESPGLQEWVTS----TELLISLDRLNTFGDDIFKDPKVLQSYYYAVSDFS 266
Query: 2312 ---KCQCNGHADTCNEQ--DGTGCPCQNNTETGTCQGSSP--SDR----------RDCYK 2354
+C+CNGHA C C CQ+NT C+ P DR +C
Sbjct: 267 VGGRCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
Query: 2355 YQCA----KC---RESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
C+ +C RE F + GG +C+ C D T+ +C
Sbjct: 327 CNCSGRSEECTFDRELFRSTGHGG-RCHH--------CRDHTAGPHC 364
Score = 38.5 bits (88), Expect = 0.093
Identities = 32/97 (32%), Positives = 35/97 (36%), Gaps = 39/97 (40%)
Query: 139 FSLCPG-GCQS---------HGQCQPP-GVCACEPGWGGPDC-------------GLQEC 174
F L PG GC+S QC P G C C PG G C G + C
Sbjct: 906 FDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 965
Query: 175 --------SAYCGSHGTCASPLGPCRCEPGFLGRACD 203
SA C +GTC C PGF G CD
Sbjct: 966 RCSPLGAASAQCHENGTCV-------CRPGFEGYKCD 995
Score = 35.4 bits (80), Expect = 0.79
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 3/49 (6%)
Query: 155 PGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRACD 203
PG +PG G C +C C G C C PG G+ACD
Sbjct: 903 PGFFDLQPGRGCRSC---KCHPLGSQEDQCHPKTGQCTCRPGVTGQACD 948
Score = 33.9 bits (76), Expect = 2.3
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 7/51 (13%)
Query: 1144 CQCNGHGDPRRGHCD-NLSG--LCFCQDHTEGAHCQLCSPGYYGDPRAGGS 1191
C+CNGH C +++G C CQ +T G C+ C P + P A G+
Sbjct: 271 CKCNGHAS----ECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGT 317
Score = 33.9 bits (76), Expect = 2.3
Identities = 20/58 (34%), Positives = 21/58 (36%), Gaps = 2/58 (3%)
Query: 140 SLCPGGCQSHGQCQP-PGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPG 196
S P C HG C P G+C C GP C Y A PC C PG
Sbjct: 703 SCVPCTCNQHGTCDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-PG 759
Score = 32.3 bits (72), Expect = 6.7
Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 8/51 (15%)
Query: 159 ACEPGW------GGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRACD 203
+C PG+ GGP C+ C HGTC G C C G +C+
Sbjct: 686 SCAPGYKREMPQGGPYASCVPCT--CNQHGTCDPNTGICVCSHHTEGPSCE 734
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 83.2 bits (204), Expect = 3e-15
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 46/199 (23%)
Query: 1080 PPTPAPGPPAPRCSRDCGCSFHSHCRKRGP-----------GFCDECQDWTWGEHCERCR 1128
P PA G A C R C C+ HS P G CD C+D T G++CERC+
Sbjct: 301 PWRPAEGQDAHECQR-CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 1129 PGSFGN----ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGY-- 1182
F N A+ C C+C+ G CD ++G C C++H +G C LC PG+
Sbjct: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 1183 --YGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAAR-------AGPGLS 1233
Y +P+ C +C LGSRR +P + R GP
Sbjct: 420 LTYANPQGCHRC--DCN-----------ILGSRRD---MPCDEESGRCLCLPNVVGPKCD 463
Query: 1234 YCV---WVVSATEELQPCA 1249
C W +++ + +PCA
Sbjct: 464 QCAPYHWKLASGQGCEPCA 482
Score = 62.0 bits (149), Expect = 8e-09
Identities = 83/370 (22%), Positives = 115/370 (31%), Gaps = 106/370 (28%)
Query: 1089 APRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERC------RPGSFGNATGSRGCR 1142
A RC+ G S + C CQ T G +CERC RP + C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVC-VCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 1143 PCQCNGHG-----DPR---------RGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRA 1188
C CNGH DP G CDN C+DHTEG +C+ C Y+ + R
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLHYFRNRRP 368
Query: 1189 GGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPC 1248
G S C +S +
Sbjct: 369 GASIQETC------------------------------------------ISCECDPDGA 386
Query: 1249 APGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRD 1305
PG C P+T + C L F G G + D +++ G RRD
Sbjct: 387 VPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGCHRCDCNIL----GSRRD 441
Query: 1306 RPLTVQA-----LSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA 1360
P ++ L ++ + W + G C +C PQ
Sbjct: 442 MPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPC------ACDPHNSLSPQCNQ 495
Query: 1361 AGAGLCRCPQGWAGPHCRMAL---CPENCNAHTGAGT--------------CNQSLGVCI 1403
G C C +G+ G C A CP+ G C+++ G C+
Sbjct: 496 F-TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL 554
Query: 1404 CAEGFGGPDC 1413
C G GP C
Sbjct: 555 CRPGLTGPRC 564
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 37/192 (19%)
Query: 1020 PRATCLNTPLSYECHCQRGYQGD----------GISHCNRTCLEDCGHGVCSGPPDFTCV 1069
P A C P++ +C C+ QG+ G+++ N C + D C
Sbjct: 388 PGAPC--DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 1070 CDLGWTSDLPPPTPAPGPPAPRCS------------RDCGCSFHSHCRKRGPGFCDEC-- 1115
+ G LP GP +C+ C C H+ + F +C
Sbjct: 446 EESGRCLCLPNVV---GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPC 502
Query: 1116 QDWTWGEHCE-----RCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHT 1170
++ G C +C ++G+ + GCR C C+ G G CD SG C C+
Sbjct: 503 REGFGGLMCSAAAIRQCPDRTYGDV--ATGCRACDCDFRGTEGPG-CDKASGRCLCRPGL 559
Query: 1171 EGAHCQLCSPGY 1182
G C C GY
Sbjct: 560 TGPRCDQCQRGY 571
Score = 49.3 bits (116), Expect = 5e-05
Identities = 52/220 (23%), Positives = 79/220 (35%), Gaps = 69/220 (31%)
Query: 2186 CRCNRHSE-CA-----------GVGARDHCLLCRNHTKGSHCEQCLPLF------VGSAV 2227
C C+ H++ CA V D C+ C+++T G +CE+C P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 2228 GGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNC 2287
C+ C C G+S C DP ++G VC NC
Sbjct: 309 DAHECQRCD--CNGHSETC----------------HFDPAVFA--ASQGAYG--GVCDNC 346
Query: 2288 QNNSYGEKCESCLQGYF-------LLDGKCTKCQCNGHADTCNEQDGT--GCPCQNNTET 2338
++++ G+ CE C YF + C C+C + DG G PC T
Sbjct: 347 RDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC--------DPDGAVPGAPCDPVTGQ 398
Query: 2339 GTCQGSSPSDRRDCYKYQCAKCRESFHG----SPLGGQQC 2374
C+ +R C C+ F G +P G +C
Sbjct: 399 CVCKEHVQGER-------CDLCKPGFTGLTYANPQGCHRC 431
Score = 48.5 bits (114), Expect = 9e-05
Identities = 51/189 (26%), Positives = 72/189 (38%), Gaps = 42/189 (22%)
Query: 2186 CRCNRHSE---------CAGVGARDH-CLLCRNHTKGSHCEQC-LPLF------------ 2222
C CN HSE A GA C CR+HT+G +CE+C L F
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 2223 -------VGSAVGGGTCRPCHAFCRGNSHICISRKEL------QMSKGEPKKYSLDPEEI 2269
AV G C P C H+ R +L ++ P+ I
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNI 435
Query: 2270 ENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-LLDGK-CTKCQCNGH---ADTCNE 2324
+ P ++E+ C N G KC+ C ++ L G+ C C C+ H + CN+
Sbjct: 436 LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQ 495
Query: 2325 QDGTGCPCQ 2333
G CPC+
Sbjct: 496 FTGQ-CPCR 503
Score = 41.2 bits (95), Expect = 0.014
Identities = 71/310 (22%), Positives = 98/310 (31%), Gaps = 86/310 (27%)
Query: 1144 CQCNGHGD---PRRGHCDNLS------GLCFCQDHTEGAHCQLCSPGYYGDP------RA 1188
C C+GH D P+ G S +C CQ +T G +C+ C+P Y P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1189 GGSCFR-ECGGRALLTNVSSVALGSRR--VGGLLP------PGGGAARAG--------PG 1231
C R +C G + + + + GG+ G R PG
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPG 369
Query: 1232 LSYCVWVVSATEELQPCAPGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGV 1288
S +S + PG C P+T + C L F G G
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGC 428
Query: 1289 VQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSC 1348
+ D +++ G RRD P + S RC
Sbjct: 429 HRCDCNIL----GSRRDMPCDEE-------------------------SGRC-------- 451
Query: 1349 PVPQECVPQDGAAGAGLCRCPQGW---AGPHCRMALCPENCNAHTGAGT-CNQSLGVCIC 1404
C+P C P W +G C P C+ H CNQ G C C
Sbjct: 452 ----LCLPNVVGPKCDQC-APYHWKLASGQGCE----PCACDPHNSLSPQCNQFTGQCPC 502
Query: 1405 AEGFGGPDCA 1414
EGFGG C+
Sbjct: 503 REGFGGLMCS 512
Score = 37.4 bits (85), Expect = 0.21
Identities = 26/106 (24%), Positives = 35/106 (33%), Gaps = 24/106 (22%)
Query: 2313 CQCNGHADTCNEQDGTG------------CPCQNNTETGTCQGSSP------------SD 2348
C C+GHAD C + G C CQ+NT C+ +P D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 2349 RRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
+C + C E+ H P + C D T NC
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNC 355
Score = 37.0 bits (84), Expect = 0.27
Identities = 46/191 (24%), Positives = 64/191 (33%), Gaps = 23/191 (12%)
Query: 2056 QATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSC---PPE 2112
Q +C LC +P + G RC + + G R + C L P
Sbjct: 406 QGERCDLC--KPGFTGLTYANPQGCHRC-DCNILGSRRDMPCDEESGRCLCLPNVVGPKC 462
Query: 2113 DECANGHHDCNETQNCHDQPHGYECSCKTGYTM----DNMTGLCRPVCAQGCVNGSCVEP 2168
D+CA H Q C C+C ++ + TG C C +G C
Sbjct: 463 DQCAPYHWKLASGQGCEP------CACDPHNSLSPQCNQFTGQCP--CREGFGGLMCSAA 514
Query: 2169 DHCRCH---FGFVGRNCSTECRCN-RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVG 2224
+C +G V C C C+ R +E G LCR G C+QC +
Sbjct: 515 AIRQCPDRTYGDVATGCRA-CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Query: 2225 SAVGGGTCRPC 2235
C PC
Sbjct: 574 RYPVCVACHPC 584
Score = 36.2 bits (82), Expect = 0.46
Identities = 35/138 (25%), Positives = 48/138 (34%), Gaps = 41/138 (29%)
Query: 101 SLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFN----ASFRFSLCPG------GCQSHG 150
++ GS R P + SG+ L N++G A + + L G C H
Sbjct: 434 NILGSRRDMPCDEESGRCL------CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHN 487
Query: 151 QCQPP-----GVCACEPGWGGPDCG---LQEC-------------SAYCGSHGT----CA 185
P G C C G+GG C +++C + C GT C
Sbjct: 488 SLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCD 547
Query: 186 SPLGPCRCEPGFLGRACD 203
G C C PG G CD
Sbjct: 548 KASGRCLCRPGLTGPRCD 565
Score = 33.9 bits (76), Expect = 2.3
Identities = 58/238 (24%), Positives = 76/238 (31%), Gaps = 57/238 (23%)
Query: 927 DDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWV 986
D +V P C G C E +Q C C P ++ P G C +
Sbjct: 384 DGAVPGAP-CDPVTGQCVCKEHVQGERCDLC----KPGFTGLT---YANPQGCHRCDCNI 435
Query: 987 GEGLGLPVALPARWAYARC--------PDVDEC-----RLGLAR-CHPRATCLNTPLSYE 1032
LG +P RC P D+C +L + C P A + LS +
Sbjct: 436 ---LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 1033 CHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRC 1092
C+ G C C E G +CS C P G A C
Sbjct: 493 CNQFTG-------QC--PCREGFGGLMCSAAAIRQC------------PDRTYGDVATGC 531
Query: 1093 SRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
R C C F GPG CD+ C+ G C++C+ G C PC
Sbjct: 532 -RACDCDFRG---TEGPG-CDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 83.2 bits (204), Expect = 3e-15
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 46/199 (23%)
Query: 1080 PPTPAPGPPAPRCSRDCGCSFHSHCRKRGP-----------GFCDECQDWTWGEHCERCR 1128
P PA G A C R C C+ HS P G CD C+D T G++CERC+
Sbjct: 301 PWRPAEGQDAHECQR-CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 1129 PGSFGN----ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGY-- 1182
F N A+ C C+C+ G CD ++G C C++H +G C LC PG+
Sbjct: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 1183 --YGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAAR-------AGPGLS 1233
Y +P+ C +C LGSRR +P + R GP
Sbjct: 420 LTYANPQGCHRC--DCN-----------ILGSRRD---MPCDEESGRCLCLPNVVGPKCD 463
Query: 1234 YCV---WVVSATEELQPCA 1249
C W +++ + +PCA
Sbjct: 464 QCAPYHWKLASGQGCEPCA 482
Score = 62.0 bits (149), Expect = 8e-09
Identities = 83/370 (22%), Positives = 115/370 (31%), Gaps = 106/370 (28%)
Query: 1089 APRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERC------RPGSFGNATGSRGCR 1142
A RC+ G S + C CQ T G +CERC RP + C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVC-VCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 1143 PCQCNGHG-----DPR---------RGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRA 1188
C CNGH DP G CDN C+DHTEG +C+ C Y+ + R
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLHYFRNRRP 368
Query: 1189 GGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPC 1248
G S C +S +
Sbjct: 369 GASIQETC------------------------------------------ISCECDPDGA 386
Query: 1249 APGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRD 1305
PG C P+T + C L F G G + D +++ G RRD
Sbjct: 387 VPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGCHRCDCNIL----GSRRD 441
Query: 1306 RPLTVQA-----LSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA 1360
P ++ L ++ + W + G C +C PQ
Sbjct: 442 MPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPC------ACDPHNSLSPQCNQ 495
Query: 1361 AGAGLCRCPQGWAGPHCRMAL---CPENCNAHTGAGT--------------CNQSLGVCI 1403
G C C +G+ G C A CP+ G C+++ G C+
Sbjct: 496 F-TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL 554
Query: 1404 CAEGFGGPDC 1413
C G GP C
Sbjct: 555 CRPGLTGPRC 564
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 37/192 (19%)
Query: 1020 PRATCLNTPLSYECHCQRGYQGD----------GISHCNRTCLEDCGHGVCSGPPDFTCV 1069
P A C P++ +C C+ QG+ G+++ N C + D C
Sbjct: 388 PGAPC--DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 1070 CDLGWTSDLPPPTPAPGPPAPRCS------------RDCGCSFHSHCRKRGPGFCDEC-- 1115
+ G LP GP +C+ C C H+ + F +C
Sbjct: 446 EESGRCLCLPNVV---GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPC 502
Query: 1116 QDWTWGEHCE-----RCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHT 1170
++ G C +C ++G+ + GCR C C+ G G CD SG C C+
Sbjct: 503 REGFGGLMCSAAAIRQCPDRTYGDV--ATGCRACDCDFRGTEGPG-CDKASGRCLCRPGL 559
Query: 1171 EGAHCQLCSPGY 1182
G C C GY
Sbjct: 560 TGPRCDQCQRGY 571
Score = 49.3 bits (116), Expect = 5e-05
Identities = 52/220 (23%), Positives = 79/220 (35%), Gaps = 69/220 (31%)
Query: 2186 CRCNRHSE-CA-----------GVGARDHCLLCRNHTKGSHCEQCLPLF------VGSAV 2227
C C+ H++ CA V D C+ C+++T G +CE+C P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 2228 GGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNC 2287
C+ C C G+S C DP ++G VC NC
Sbjct: 309 DAHECQRCD--CNGHSETC----------------HFDPAVFA--ASQGAYG--GVCDNC 346
Query: 2288 QNNSYGEKCESCLQGYF-------LLDGKCTKCQCNGHADTCNEQDGT--GCPCQNNTET 2338
++++ G+ CE C YF + C C+C + DG G PC T
Sbjct: 347 RDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC--------DPDGAVPGAPCDPVTGQ 398
Query: 2339 GTCQGSSPSDRRDCYKYQCAKCRESFHG----SPLGGQQC 2374
C+ +R C C+ F G +P G +C
Sbjct: 399 CVCKEHVQGER-------CDLCKPGFTGLTYANPQGCHRC 431
Score = 48.5 bits (114), Expect = 9e-05
Identities = 51/189 (26%), Positives = 72/189 (38%), Gaps = 42/189 (22%)
Query: 2186 CRCNRHSE---------CAGVGARDH-CLLCRNHTKGSHCEQC-LPLF------------ 2222
C CN HSE A GA C CR+HT+G +CE+C L F
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 2223 -------VGSAVGGGTCRPCHAFCRGNSHICISRKEL------QMSKGEPKKYSLDPEEI 2269
AV G C P C H+ R +L ++ P+ I
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNI 435
Query: 2270 ENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-LLDGK-CTKCQCNGH---ADTCNE 2324
+ P ++E+ C N G KC+ C ++ L G+ C C C+ H + CN+
Sbjct: 436 LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQ 495
Query: 2325 QDGTGCPCQ 2333
G CPC+
Sbjct: 496 FTGQ-CPCR 503
Score = 41.2 bits (95), Expect = 0.014
Identities = 71/310 (22%), Positives = 98/310 (31%), Gaps = 86/310 (27%)
Query: 1144 CQCNGHGD---PRRGHCDNLS------GLCFCQDHTEGAHCQLCSPGYYGDP------RA 1188
C C+GH D P+ G S +C CQ +T G +C+ C+P Y P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1189 GGSCFR-ECGGRALLTNVSSVALGSRR--VGGLLP------PGGGAARAG--------PG 1231
C R +C G + + + + GG+ G R PG
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPG 369
Query: 1232 LSYCVWVVSATEELQPCAPGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGV 1288
S +S + PG C P+T + C L F G G
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGC 428
Query: 1289 VQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSC 1348
+ D +++ G RRD P + S RC
Sbjct: 429 HRCDCNIL----GSRRDMPCDEE-------------------------SGRC-------- 451
Query: 1349 PVPQECVPQDGAAGAGLCRCPQGW---AGPHCRMALCPENCNAHTGAGT-CNQSLGVCIC 1404
C+P C P W +G C P C+ H CNQ G C C
Sbjct: 452 ----LCLPNVVGPKCDQC-APYHWKLASGQGCE----PCACDPHNSLSPQCNQFTGQCPC 502
Query: 1405 AEGFGGPDCA 1414
EGFGG C+
Sbjct: 503 REGFGGLMCS 512
Score = 37.4 bits (85), Expect = 0.21
Identities = 26/106 (24%), Positives = 35/106 (33%), Gaps = 24/106 (22%)
Query: 2313 CQCNGHADTCNEQDGTG------------CPCQNNTETGTCQGSSP------------SD 2348
C C+GHAD C + G C CQ+NT C+ +P D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 2349 RRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
+C + C E+ H P + C D T NC
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNC 355
Score = 37.0 bits (84), Expect = 0.27
Identities = 46/191 (24%), Positives = 64/191 (33%), Gaps = 23/191 (12%)
Query: 2056 QATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSC---PPE 2112
Q +C LC +P + G RC + + G R + C L P
Sbjct: 406 QGERCDLC--KPGFTGLTYANPQGCHRC-DCNILGSRRDMPCDEESGRCLCLPNVVGPKC 462
Query: 2113 DECANGHHDCNETQNCHDQPHGYECSCKTGYTM----DNMTGLCRPVCAQGCVNGSCVEP 2168
D+CA H Q C C+C ++ + TG C C +G C
Sbjct: 463 DQCAPYHWKLASGQGCEP------CACDPHNSLSPQCNQFTGQCP--CREGFGGLMCSAA 514
Query: 2169 DHCRCH---FGFVGRNCSTECRCN-RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVG 2224
+C +G V C C C+ R +E G LCR G C+QC +
Sbjct: 515 AIRQCPDRTYGDVATGCRA-CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Query: 2225 SAVGGGTCRPC 2235
C PC
Sbjct: 574 RYPVCVACHPC 584
Score = 36.2 bits (82), Expect = 0.46
Identities = 35/138 (25%), Positives = 48/138 (34%), Gaps = 41/138 (29%)
Query: 101 SLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFN----ASFRFSLCPG------GCQSHG 150
++ GS R P + SG+ L N++G A + + L G C H
Sbjct: 434 NILGSRRDMPCDEESGRCL------CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHN 487
Query: 151 QCQPP-----GVCACEPGWGGPDCG---LQEC-------------SAYCGSHGT----CA 185
P G C C G+GG C +++C + C GT C
Sbjct: 488 SLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCD 547
Query: 186 SPLGPCRCEPGFLGRACD 203
G C C PG G CD
Sbjct: 548 KASGRCLCRPGLTGPRCD 565
Score = 33.9 bits (76), Expect = 2.3
Identities = 58/238 (24%), Positives = 76/238 (31%), Gaps = 57/238 (23%)
Query: 927 DDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWV 986
D +V P C G C E +Q C C P ++ P G C +
Sbjct: 384 DGAVPGAP-CDPVTGQCVCKEHVQGERCDLC----KPGFTGLT---YANPQGCHRCDCNI 435
Query: 987 GEGLGLPVALPARWAYARC--------PDVDEC-----RLGLAR-CHPRATCLNTPLSYE 1032
LG +P RC P D+C +L + C P A + LS +
Sbjct: 436 ---LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 1033 CHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRC 1092
C+ G C C E G +CS C P G A C
Sbjct: 493 CNQFTG-------QC--PCREGFGGLMCSAAAIRQC------------PDRTYGDVATGC 531
Query: 1093 SRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
R C C F GPG CD+ C+ G C++C+ G C PC
Sbjct: 532 -RACDCDFRG---TEGPG-CDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 83.2 bits (204), Expect = 3e-15
Identities = 60/199 (30%), Positives = 84/199 (42%), Gaps = 46/199 (23%)
Query: 1080 PPTPAPGPPAPRCSRDCGCSFHSHCRKRGP-----------GFCDECQDWTWGEHCERCR 1128
P PA G A C R C C+ HS P G CD C+D T G++CERC+
Sbjct: 301 PWRPAEGQDAHECQR-CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
Query: 1129 PGSFGN----ATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGY-- 1182
F N A+ C C+C+ G CD ++G C C++H +G C LC PG+
Sbjct: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 1183 --YGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAAR-------AGPGLS 1233
Y +P+ C +C LGSRR +P + R GP
Sbjct: 420 LTYANPQGCHRC--DCN-----------ILGSRRD---MPCDEESGRCLCLPNVVGPKCD 463
Query: 1234 YCV---WVVSATEELQPCA 1249
C W +++ + +PCA
Sbjct: 464 QCAPYHWKLASGQGCEPCA 482
Score = 62.0 bits (149), Expect = 8e-09
Identities = 83/370 (22%), Positives = 115/370 (31%), Gaps = 106/370 (28%)
Query: 1089 APRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERC------RPGSFGNATGSRGCR 1142
A RC+ G S + C CQ T G +CERC RP + C+
Sbjct: 256 ADRCAPKPGASAGPSTAVQVHDVC-VCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ 314
Query: 1143 PCQCNGHG-----DPR---------RGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRA 1188
C CNGH DP G CDN C+DHTEG +C+ C Y+ + R
Sbjct: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLHYFRNRRP 368
Query: 1189 GGSCFRECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPC 1248
G S C +S +
Sbjct: 369 GASIQETC------------------------------------------ISCECDPDGA 386
Query: 1249 APGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFCGQRRD 1305
PG C P+T + C L F G G + D +++ G RRD
Sbjct: 387 VPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGCHRCDCNIL----GSRRD 441
Query: 1306 RPLTVQA-----LSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA 1360
P ++ L ++ + W + G C +C PQ
Sbjct: 442 MPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPC------ACDPHNSLSPQCNQ 495
Query: 1361 AGAGLCRCPQGWAGPHCRMAL---CPENCNAHTGAGT--------------CNQSLGVCI 1403
G C C +G+ G C A CP+ G C+++ G C+
Sbjct: 496 F-TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL 554
Query: 1404 CAEGFGGPDC 1413
C G GP C
Sbjct: 555 CRPGLTGPRC 564
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 37/192 (19%)
Query: 1020 PRATCLNTPLSYECHCQRGYQGD----------GISHCNRTCLEDCGHGVCSGPPDFTCV 1069
P A C P++ +C C+ QG+ G+++ N C + D C
Sbjct: 388 PGAPC--DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCD 445
Query: 1070 CDLGWTSDLPPPTPAPGPPAPRCS------------RDCGCSFHSHCRKRGPGFCDEC-- 1115
+ G LP GP +C+ C C H+ + F +C
Sbjct: 446 EESGRCLCLPNVV---GPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPC 502
Query: 1116 QDWTWGEHCE-----RCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHT 1170
++ G C +C ++G+ + GCR C C+ G G CD SG C C+
Sbjct: 503 REGFGGLMCSAAAIRQCPDRTYGDV--ATGCRACDCDFRGTEGPG-CDKASGRCLCRPGL 559
Query: 1171 EGAHCQLCSPGY 1182
G C C GY
Sbjct: 560 TGPRCDQCQRGY 571
Score = 49.3 bits (116), Expect = 5e-05
Identities = 52/220 (23%), Positives = 79/220 (35%), Gaps = 69/220 (31%)
Query: 2186 CRCNRHSE-CA-----------GVGARDHCLLCRNHTKGSHCEQCLPLF------VGSAV 2227
C C+ H++ CA V D C+ C+++T G +CE+C P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 2228 GGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNC 2287
C+ C C G+S C DP ++G VC NC
Sbjct: 309 DAHECQRCD--CNGHSETC----------------HFDPAVFA--ASQGAYG--GVCDNC 346
Query: 2288 QNNSYGEKCESCLQGYF-------LLDGKCTKCQCNGHADTCNEQDGT--GCPCQNNTET 2338
++++ G+ CE C YF + C C+C + DG G PC T
Sbjct: 347 RDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC--------DPDGAVPGAPCDPVTGQ 398
Query: 2339 GTCQGSSPSDRRDCYKYQCAKCRESFHG----SPLGGQQC 2374
C+ +R C C+ F G +P G +C
Sbjct: 399 CVCKEHVQGER-------CDLCKPGFTGLTYANPQGCHRC 431
Score = 48.5 bits (114), Expect = 9e-05
Identities = 51/189 (26%), Positives = 72/189 (38%), Gaps = 42/189 (22%)
Query: 2186 CRCNRHSE---------CAGVGARDH-CLLCRNHTKGSHCEQC-LPLF------------ 2222
C CN HSE A GA C CR+HT+G +CE+C L F
Sbjct: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
Query: 2223 -------VGSAVGGGTCRPCHAFCRGNSHICISRKEL------QMSKGEPKKYSLDPEEI 2269
AV G C P C H+ R +L ++ P+ I
Sbjct: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNI 435
Query: 2270 ENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF-LLDGK-CTKCQCNGH---ADTCNE 2324
+ P ++E+ C N G KC+ C ++ L G+ C C C+ H + CN+
Sbjct: 436 LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQ 495
Query: 2325 QDGTGCPCQ 2333
G CPC+
Sbjct: 496 FTGQ-CPCR 503
Score = 41.2 bits (95), Expect = 0.014
Identities = 71/310 (22%), Positives = 98/310 (31%), Gaps = 86/310 (27%)
Query: 1144 CQCNGHGD---PRRGHCDNLS------GLCFCQDHTEGAHCQLCSPGYYGDP------RA 1188
C C+GH D P+ G S +C CQ +T G +C+ C+P Y P +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 1189 GGSCFR-ECGGRALLTNVSSVALGSRR--VGGLLP------PGGGAARAG--------PG 1231
C R +C G + + + + GG+ G R PG
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPG 369
Query: 1232 LSYCVWVVSATEELQPCAPGTLCPPLT---LTFSPDSSTPCTLSYVLAFDGFPRFLDTGV 1288
S +S + PG C P+T + C L F G G
Sbjct: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP-GFTGLTYANPQGC 428
Query: 1289 VQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSC 1348
+ D +++ G RRD P + S RC
Sbjct: 429 HRCDCNIL----GSRRDMPCDEE-------------------------SGRC-------- 451
Query: 1349 PVPQECVPQDGAAGAGLCRCPQGW---AGPHCRMALCPENCNAHTGAGT-CNQSLGVCIC 1404
C+P C P W +G C P C+ H CNQ G C C
Sbjct: 452 ----LCLPNVVGPKCDQC-APYHWKLASGQGCE----PCACDPHNSLSPQCNQFTGQCPC 502
Query: 1405 AEGFGGPDCA 1414
EGFGG C+
Sbjct: 503 REGFGGLMCS 512
Score = 37.4 bits (85), Expect = 0.21
Identities = 26/106 (24%), Positives = 35/106 (33%), Gaps = 24/106 (22%)
Query: 2313 CQCNGHADTCNEQDGTG------------CPCQNNTETGTCQGSSP------------SD 2348
C C+GHAD C + G C CQ+NT C+ +P D
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 2349 RRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNC 2394
+C + C E+ H P + C D T NC
Sbjct: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNC 355
Score = 37.0 bits (84), Expect = 0.27
Identities = 46/191 (24%), Positives = 64/191 (33%), Gaps = 23/191 (12%)
Query: 2056 QATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSC---PPE 2112
Q +C LC +P + G RC + + G R + C L P
Sbjct: 406 QGERCDLC--KPGFTGLTYANPQGCHRC-DCNILGSRRDMPCDEESGRCLCLPNVVGPKC 462
Query: 2113 DECANGHHDCNETQNCHDQPHGYECSCKTGYTM----DNMTGLCRPVCAQGCVNGSCVEP 2168
D+CA H Q C C+C ++ + TG C C +G C
Sbjct: 463 DQCAPYHWKLASGQGCEP------CACDPHNSLSPQCNQFTGQCP--CREGFGGLMCSAA 514
Query: 2169 DHCRCH---FGFVGRNCSTECRCN-RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVG 2224
+C +G V C C C+ R +E G LCR G C+QC +
Sbjct: 515 AIRQCPDRTYGDVATGCRA-CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Query: 2225 SAVGGGTCRPC 2235
C PC
Sbjct: 574 RYPVCVACHPC 584
Score = 36.2 bits (82), Expect = 0.46
Identities = 35/138 (25%), Positives = 48/138 (34%), Gaps = 41/138 (29%)
Query: 101 SLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFN----ASFRFSLCPG------GCQSHG 150
++ GS R P + SG+ L N++G A + + L G C H
Sbjct: 434 NILGSRRDMPCDEESGRCL------CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHN 487
Query: 151 QCQPP-----GVCACEPGWGGPDCG---LQEC-------------SAYCGSHGT----CA 185
P G C C G+GG C +++C + C GT C
Sbjct: 488 SLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCD 547
Query: 186 SPLGPCRCEPGFLGRACD 203
G C C PG G CD
Sbjct: 548 KASGRCLCRPGLTGPRCD 565
Score = 33.9 bits (76), Expect = 2.3
Identities = 58/238 (24%), Positives = 76/238 (31%), Gaps = 57/238 (23%)
Query: 927 DDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWV 986
D +V P C G C E +Q C C P ++ P G C +
Sbjct: 384 DGAVPGAP-CDPVTGQCVCKEHVQGERCDLC----KPGFTGLT---YANPQGCHRCDCNI 435
Query: 987 GEGLGLPVALPARWAYARC--------PDVDEC-----RLGLAR-CHPRATCLNTPLSYE 1032
LG +P RC P D+C +L + C P A + LS +
Sbjct: 436 ---LGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
Query: 1033 CHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRC 1092
C+ G C C E G +CS C P G A C
Sbjct: 493 CNQFTG-------QC--PCREGFGGLMCSAAAIRQC------------PDRTYGDVATGC 531
Query: 1093 SRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
R C C F GPG CD+ C+ G C++C+ G C PC
Sbjct: 532 -RACDCDFRG---TEGPG-CDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 83.2 bits (204), Expect = 3e-15
Identities = 68/233 (29%), Positives = 91/233 (39%), Gaps = 51/233 (21%)
Query: 997 PARWAYARCP-DVDECRLGLAR---CHPRATCLNTPLSYECHCQRGYQGDGISH----CN 1048
P +W C DV+EC + C TC+NT SY CHC G + C
Sbjct: 159 PPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCE 218
Query: 1049 RTCLEDCGHGVC-------SGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFH 1101
+ C HG+C +G P ++CVCD GW +P PA RD CSF
Sbjct: 219 GGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMF-------SPNSPACTLDRD-ECSFQ 270
Query: 1102 SHCRKRGPGFCD---ECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCD 1158
PG C +C + +C C G GN C+ N G C
Sbjct: 271 -------PGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGG------C- 316
Query: 1159 NLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALG 1211
+++ C + +HCQ C PGY GD R LT++ SV+ G
Sbjct: 317 SVAPPVECVNTPGSSHCQACPPGYQGDGRV-----------CTLTDICSVSNG 358
Score = 67.0 bits (162), Expect = 2e-10
Identities = 49/133 (36%), Positives = 67/133 (50%), Gaps = 12/133 (9%)
Query: 17 VLGSLSPGARAGDCK-GQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFL 75
VL +++PGA G + G V +PG+ +YS +C WLI+AP + L+ L
Sbjct: 1969 VLPTIAPGACGGFLRTGDAPVFLFSPGW----PDSYSNRVDCTWLIQAPDST--VELNIL 2022
Query: 76 FLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLL 131
LD E C YD L + DGD+ LA L G P PI ++ M + SD++
Sbjct: 2023 SLDIESHRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRA 2082
Query: 132 GFNASFRFSLCPG 144
GFNASF S C G
Sbjct: 2083 GFNASFHKS-CGG 2094
Score = 62.8 bits (151), Expect = 5e-09
Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 45 TDGAGNYSVNGNCEWLIEAPSPQ------HRILLDFLFLDTECTYDYLFVYDGDSPRGPL 98
+D G Y N NC W+I AP + + L+ C YDY+ +YDGDS L
Sbjct: 3173 SDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYDGDSENANL 3232
Query: 99 LASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQPPGVC 158
+ GST P P +S + + SD GFNA++ P G + P +
Sbjct: 3233 AGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIMDMPCGGTYNATWTPQNIS 3292
Query: 159 ACEPGWGGPDCGLQECS 175
+ P PD C+
Sbjct: 3293 S--PNSSDPDVPFSICT 3307
Score = 57.4 bits (137), Expect = 2e-07
Identities = 42/119 (35%), Positives = 59/119 (49%), Gaps = 9/119 (7%)
Query: 36 VLREAPGFVTDGAGNYSVNGN---CEWLIEAPSPQHRILLDFLFLD----TECTYDYLFV 88
V + G +T A +Y+ N C + I S I L F D T C++DYL +
Sbjct: 3040 VFNFSSGIITSPAYSYADYPNDMHCLYTITV-SDDKVIELKFSDFDVVPSTSCSHDYLAI 3098
Query: 89 YDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCP-GGC 146
YDG + PLL GS RPP +++S+ MLL +D+ G+ SFR +L P GC
Sbjct: 3099 YDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGC 3157
Score = 56.6 bits (135), Expect = 3e-07
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 4/100 (4%)
Query: 50 NYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGS 105
NY N NC W+I+A P + I L F + E C D++ + DG PL G+
Sbjct: 1640 NYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGT 1699
Query: 106 TRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGG 145
P PI + S + L SD++ + GF+ + S+ G
Sbjct: 1700 DMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACG 1739
Score = 53.5 bits (127), Expect = 3e-06
Identities = 34/111 (30%), Positives = 59/111 (53%), Gaps = 9/111 (8%)
Query: 40 APGFVTDGAGNYSVNGNCEWLIEAPSPQH---RILLDFLFLDT--ECTYDYLFVYDGDSP 94
+PG+ DG NYS N NCEW + P+ + I + +L++ +C +D L GD+
Sbjct: 2584 SPGY--DGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFRVGDAD 2641
Query: 95 RGPLLASLSGSTRPP-PIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPG 144
GPL+ L G ++P P+ ++ +H ++ +GF+A + F+ C G
Sbjct: 2642 -GPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGG 2691
Score = 52.4 bits (124), Expect = 6e-06
Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 8/113 (7%)
Query: 39 EAPGFVT--DGAGNYSVNGNCEWLIEAPSPQHRILLDF-----LFLDTECTYDYLFVYDG 91
++ G+VT + NY + +C W++ AP P+ RI L F + + CT +YL + DG
Sbjct: 2227 DSAGYVTSPNHPHNYPPHADCIWILAAP-PETRIQLQFEDRFDIEVTPNCTSNYLELRDG 2285
Query: 92 DSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPG 144
P+L+ G++ P +S M L SD + +GF A + + C G
Sbjct: 2286 VDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGG 2338
Score = 51.2 bits (121), Expect = 1e-05
Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 9/94 (9%)
Query: 51 YSVNGNCEWLIEAPSPQHRILLDFLFLD------TECTYDYLFVYDGDSPRGPLLASLSG 104
Y + C W +++ H + F D CT DYL VYDG S LL L G
Sbjct: 1185 YYHSSECYWWLKS---SHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCG 1241
Query: 105 STRPPPIEASSGKMLLHLFSDANYNLLGFNASFR 138
+PP I +S M + L +D GF A +R
Sbjct: 1242 DEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1275
Score = 46.6 bits (109), Expect = 3e-04
Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 11/140 (7%)
Query: 39 EAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSP 94
++PG+ GNY +C W++ SP + F L E C DYL + DG
Sbjct: 602 KSPGY----PGNYPPGRDCVWIV-VTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLY 656
Query: 95 RGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQCQP 154
+ PLL + PP++ + +H SD+ + GF+ ++ S P + G
Sbjct: 657 QDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYLTS--PSDLRCGGNYTD 714
Query: 155 PGVCACEPGWGGPDCGLQEC 174
P P GP ++C
Sbjct: 715 PEGELFLPELSGPFTHTRQC 734
Score = 45.1 bits (105), Expect = 0.001
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 56 NCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGSTRPPPI 111
+C L+EAP H I L F D E C +D + V +G SP P++ G++ P I
Sbjct: 2714 HCSSLLEAPQG-HTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTI 2772
Query: 112 EASSGKMLLHLFSDANYNLLGFNASF 137
++ S ++++ SD + GF A++
Sbjct: 2773 QSGSNQLVVTFNSDHSLQGGGFYATW 2798
Score = 43.9 bits (102), Expect = 0.002
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 11/114 (9%)
Query: 17 VLGSLSPGARAGDCKGQRQVLREAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLF 76
++ + SP G G R +PG+ G Y N CEW++ AP+ + + ++F F
Sbjct: 3502 IIWTSSPSGCGGTLYGDRGSFT-SPGY----PGTYPNNTYCEWVLVAPAGR-LVTINFYF 3555
Query: 77 LDT----ECTYDYLFVYDGDSPRGPLLAS-LSGSTRPPPIEASSGKMLLHLFSD 125
+ +C +YL +YDG + P G T P ASS ++ + +D
Sbjct: 3556 ISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHAD 3609
Score = 43.5 bits (101), Expect = 0.003
Identities = 27/81 (33%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 56 NCEWLIEAPSPQH-RILLDFLFLDT--ECTYDYLFVYDGDSPRGPLLASLSGSTRPPPIE 112
NC W+I+ + RI F L++ C +++L VYDGDS L GS+ P +
Sbjct: 499 NCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELL 558
Query: 113 ASSGKMLLHLFSDANYNLLGF 133
+S + HL+S+ N GF
Sbjct: 559 SSDNALYFHLYSEHLRNGRGF 579
Score = 43.1 bits (100), Expect = 0.004
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 16/143 (11%)
Query: 40 APGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPR 95
+PGF Y N C W I P I L D E C +D L +Y G
Sbjct: 1404 SPGF----PNRYPPNKECIWYIRT-DPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFH 1458
Query: 96 GPLLASLSGSTRPP-PIEASS--GKMLLHLFSDANYNLLGFNASFRFSLCPGGCQSHGQC 152
P +A L P P++ SS ++ + +D + N GFNAS++ GGC G
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ--AVTGGC--GGIF 1514
Query: 153 QPPGVCACEPGWGGPDCGLQECS 175
Q P P + P +CS
Sbjct: 1515 QAPSGEIHSPNYPSPYRSNTDCS 1537
Score = 42.7 bits (99), Expect = 0.005
Identities = 35/105 (33%), Positives = 49/105 (46%), Gaps = 9/105 (8%)
Query: 35 QVLREAPGFV-TDGAGNYSVNG-NCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFV 88
++L E+ G + + G N +G NC W I P H I L F E CT DYL V
Sbjct: 934 EILTESTGTIQSPGHPNVYPHGINCTWHILV-QPNHLIHLMFETFHLEFHYNCTNDYLEV 992
Query: 89 YDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGF 133
YD DS L G + PP + +S ++L +D++ GF
Sbjct: 993 YDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 1035
Score = 42.7 bits (99), Expect = 0.005
Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 15/128 (11%)
Query: 50 NYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGS 105
NY N N +W + + H + L +D E C YD L +YDG S L+ + G
Sbjct: 1871 NYPHNSNYQWTVNV-NASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCG- 1928
Query: 106 TRPPPIEASSGKMLLHLFSDANYNLLGFNASFRF---------SLCPGGCQSHGQCQPPG 156
T+ ++ + H +SD++ + GF + ++ PG C +
Sbjct: 1929 TQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGACGGFLRTGDAP 1988
Query: 157 VCACEPGW 164
V PGW
Sbjct: 1989 VFLFSPGW 1996
Score = 42.0 bits (97), Expect = 0.008
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 13/70 (18%)
Query: 146 CQSHGQC---QPPGVCACEPGWGGPDCG--LQECSAY------CGSHGTCASPLG--PCR 192
CQ+ G C C C P W GP C + EC Y C + GTC + +G C
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCH 200
Query: 193 CEPGFLGRAC 202
C P G C
Sbjct: 201 CPPETYGPQC 210
Score = 42.0 bits (97), Expect = 0.008
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 8/79 (10%)
Query: 1005 CPDVDECRLGLARCHPRATCLNTPLSYE-CHCQRGYQGDGIS-----HCNRTCL-EDCGH 1057
C D C + CHP A+C +T S C C GY G+G + CL C +
Sbjct: 347 CTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLN 406
Query: 1058 GVC-SGPPDFTCVCDLGWT 1075
G C + C CD GWT
Sbjct: 407 GQCIDTVSGYFCKCDSGWT 425
Score = 41.6 bits (96), Expect = 0.011
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 51 YSVNGNCEWLIEAPSPQHRILLDFLFLDTECTYDYLFVYDGDSPRGPLLASLSGSTR-PP 109
Y N +C W+I HR+LL+F D E + YDG S LA G +
Sbjct: 1530 YRSNTDCSWVIRVDR-NHRVLLNFTDFDLEPQDSCIMAYDGLSSTMSRLARTCGREQLAN 1588
Query: 110 PIEASSGKMLLHLFSDANYNLLGFNASFR 138
PI +S + L S + GF A FR
Sbjct: 1589 PIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1617
Score = 41.6 bits (96), Expect = 0.011
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 7/101 (6%)
Query: 50 NYSVNGNCEWLIEAPSPQHRILLDFLFL----DTECTYDYLFVYDGDSPRGPLLASLSGS 105
NY + +C + AP H I L F L EC D+L V +G + PLL G+
Sbjct: 3414 NYDNDKDCTVTLTAPQ-NHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGT 3472
Query: 106 TRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPGGC 146
P P+ + + ++ L SD+ + G+ + S P GC
Sbjct: 3473 LLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSS--PSGC 3511
Score = 41.2 bits (95), Expect = 0.014
Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
Query: 51 YSVNGNCEWLIEAPSPQHRILLDFLFLDTE--------CTYDYLFVYDGDSPRGPLLASL 102
Y N NC ++IEA +P +LL F+ E C D + + G S A++
Sbjct: 2940 YDNNMNCTYVIEA-NPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMSTPFATV 2998
Query: 103 SGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSLCPG 144
G P P+ + G +LL+ +S+ GF S+R C G
Sbjct: 2999 CGDEMPAPLTIA-GPVLLNFYSNEQITDFGFKFSYRIISCGG 3039
Score = 39.7 bits (91), Expect = 0.042
Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 34/195 (17%)
Query: 2020 SSLQQCLSP--SYLPLRCMAG--GCGRLLRGPESCSL---GCAQA--TQCALCLRRPHCG 2070
S+L QC + S+ C G G G + C + GC+ A +C HC
Sbjct: 275 STLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHCQ 334
Query: 2071 WCAWGGQDGGGRCMEGGLSGPRDG-----LTCGRPGASWAFLSCPPEDECANGH------ 2119
C G Q G C + +G +C S +C P NG+
Sbjct: 335 ACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP-GYTGNGYGPNGCV 393
Query: 2120 --------HDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSC----VE 2167
H C Q C D GY C C +G+T N T + C+NG V+
Sbjct: 394 QLSNICLSHPCLNGQ-CIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVD 452
Query: 2168 PDHCRCHFGFVGRNC 2182
C C + G C
Sbjct: 453 SFSCECTRLWTGALC 467
Score = 39.7 bits (91), Expect = 0.042
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 51 YSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGST 106
YS N +C W I A + + + FL D E C+ DYL +YDG G G
Sbjct: 1300 YSENQHCNWTIRATTG-NTVNYTFLAFDLEHHINCSTDYLELYDGPRQMG----RYCGVD 1354
Query: 107 RPPPIEASSGKMLLHLFSD 125
PPP +S K+ + L +D
Sbjct: 1355 LPPPGSTTSSKLQVLLLTD 1373
Score = 39.3 bits (90), Expect = 0.055
Identities = 75/334 (22%), Positives = 107/334 (32%), Gaps = 68/334 (20%)
Query: 2013 WQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWC 2072
W+ + S+ + +C S PL C GG G SC C T C +
Sbjct: 162 WKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCH--CPPETYGPQCASK------ 213
Query: 2073 AWGGQDGG--GRCMEG--------GLSGPRDGLTCGRPGASWAFLSCPP-----EDECAN 2117
+ +GG RC+ G P+ C A W F P DEC+
Sbjct: 214 -YDDCEGGSVARCVHGICEDLMREQAGEPKYSCVC---DAGWMFSPNSPACTLDRDECSF 269
Query: 2118 GHHDCNETQNCHDQPHGYEC-SCKTGYTMDNMTGLCRPVCAQGCVNGSC-VEP------- 2168
C+ C + + C +C TG+ + +C + NG C V P
Sbjct: 270 QPGPCSTLVQCFNTQGSFYCGACPTGWQGNGY--ICEDINECEINNGGCSVAPPVECVNT 327
Query: 2169 ---DHCR-CHFGFV--GRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLF 2222
HC+ C G+ GR C+ C+ G C + CLP +
Sbjct: 328 PGSSHCQACPPGYQGDGRVCTLTDICS-----VSNGGCHPDASCSSTLGSLPLCTCLPGY 382
Query: 2223 VGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEA 2282
G+ G C C SH C++ + + G K W
Sbjct: 383 TGNGYGPNGCVQLSNICL--SHPCLNGQCIDTVSGYFCKCD------SGWTG-------- 426
Query: 2283 VCVNCQNNSYGEKCESCLQGYFLLDG-KCTKCQC 2315
VNC N CL G +DG C+C
Sbjct: 427 --VNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Score = 38.5 bits (88), Expect = 0.093
Identities = 78/323 (24%), Positives = 108/323 (33%), Gaps = 51/323 (15%)
Query: 779 SSCTSYSSC-LGCLADQGCGWCLTSATCHL--RQGGAHCG---DDGAGGSLLVLVPTLCP 832
+ C YS L C C + S +CH G C DD GGS+ V +C
Sbjct: 172 NECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICE 231
Query: 833 -LCEEH--RDCHACTQDPFCEWHQSTSRKGDAACSRRGRGRGALKSPEEC---PPLCSQR 886
L E ++C D W S + AC+ +EC P CS
Sbjct: 232 DLMREQAGEPKYSCVCD--AGWMFSPN---SPACTL---------DRDECSFQPGPCSTL 277
Query: 887 LTCEDCLANSSQCAWCQSTHTCFLFAAYLAR------YPHGGCRGWDDSVHSEPRCRSCD 940
+ C N+ +C + T + Y+ +GGC SV C +
Sbjct: 278 VQC----FNTQGSFYCGACPTGWQGNGYICEDINECEINNGGC-----SVAPPVECVNTP 328
Query: 941 GFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARW 1000
G C C G+ G+ TL G +CS +G L L LP
Sbjct: 329 GSSHCQACPP----GYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGS-LPLCTCLPGYT 383
Query: 1001 AYARCPDVDECRLGLARCHP--RATCLNTPLSYECHCQRGYQGDGISHCNRTCLED--CG 1056
P+ + HP C++T Y C C G+ G + CL +
Sbjct: 384 GNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLN 443
Query: 1057 HGVC-SGPPDFTCVCDLGWTSDL 1078
G C G F+C C WT L
Sbjct: 444 GGTCVDGVDSFSCECTRLWTGAL 466
Score = 37.4 bits (85), Expect = 0.21
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 1366 CRCPQGWAGPHCRMALCPENCNAHTG-------AGTCNQSLG--VCICAEGFGGPDCATK 1416
C CP W GP C + C ++G GTC ++G C C GP CA+K
Sbjct: 156 CICPPQWKGPLCSADV--NECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPETYGPQCASK 213
Query: 1417 LD 1418
D
Sbjct: 214 YD 215
Score = 37.0 bits (84), Expect = 0.27
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 51 YSVNGNCEWLIEAPSPQHRILLDF----LFLDTECTYDYLFVYDGDSPRGPLLASLSGST 106
Y N CEW ++ S H + + F L + C D++ ++D + G +L G+T
Sbjct: 2357 YRDNLFCEWHLQGLSG-HYLTISFEDFNLQNSSGCEKDFVEIWDNHTS-GNILGRYCGNT 2414
Query: 107 RPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSL--CPGGCQ 147
P I+ SS ++ +D + GF F S+ C G Q
Sbjct: 2415 IPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ 2457
Score = 35.0 bits (79), Expect = 1.0
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 84 DYLFVYDGDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNA 135
D+L + DG + PLL GS PP I + S K+ L SD GF+A
Sbjct: 1105 DFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 33.5 bits (75), Expect = 3.0
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 18/117 (15%)
Query: 1235 CVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRS 1294
C+W+++A E + + F + + CT +Y+ DG V SD
Sbjct: 2247 CIWILAAPPETR------IQLQFEDRFDIEVTPNCTSNYLELRDG---------VDSDAP 2291
Query: 1295 LIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSW-GFNASVGSARCGSGGPGSCPV 1350
+++ FCG P + + ++ L + ++ S + GF A A+CG PG V
Sbjct: 2292 ILSKFCGT--SLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGV 2346
Score = 32.0 bits (71), Expect = 8.7
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%)
Query: 146 CQSH----GQCQPPG---VCACEPGWGGPDC--GLQEC-SAYCGSHGTCASPLG--PCRC 193
C SH GQC C C+ GW G +C + EC S C + GTC + C C
Sbjct: 399 CLSHPCLNGQCIDTVSGYFCKCDSGWTGVNCTENINECLSNPCLNGGTCVDGVDSFSCEC 458
Query: 194 EPGFLGRACDL 204
+ G C +
Sbjct: 459 TRLWTGALCQV 469
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 82.8 bits (203), Expect = 4e-15
Identities = 54/153 (35%), Positives = 71/153 (46%), Gaps = 29/153 (18%)
Query: 1060 CSGPPDF---TCV-CDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDEC 1115
CS PP + +C CD G+T TP+ G C R C C HS + G C C
Sbjct: 1126 CSCPPGYRGPSCQDCDTGYTR-----TPS-GLYLGTCER-CSCHGHSEACEPETGACQGC 1178
Query: 1116 QDWTWGEHCERCRPGSFGNATGS--RGCRPCQCNGHGDPRRGHCDNLSGLCF-------- 1165
Q T G CE+C+PG +G+A + C+ C C +GDP G + CF
Sbjct: 1179 QHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPC--YGDPAAGQA---AHTCFLDTDGHPT 1233
Query: 1166 ---CQDHTEGAHCQLCSPGYYGDPRAGGSCFRE 1195
C G HC+ C+PGYYG+P G C R+
Sbjct: 1234 CDACSPGHSGRHCERCAPGYYGNPSQGQPCQRD 1266
Score = 69.7 bits (169), Expect = 4e-11
Identities = 49/170 (28%), Positives = 71/170 (41%), Gaps = 23/170 (13%)
Query: 1096 CGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGS--RGCRPCQC--NGHGD 1151
C C+ HS G C +CQ GE CE C PG +G+AT C+PC C +
Sbjct: 1563 CECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPEN 1622
Query: 1152 PRRGHCDNLSG----LCFCQDHTEGAHCQLCSPGYYGDPRA-GGSCFRECGGRALLTNVS 1206
C++L C+ G +C+ C PGY G+P GG C E TN +
Sbjct: 1623 MFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPE-------TNQA 1675
Query: 1207 SVALGSRRVGGLLPPGGGAAR----AGPGLSYCVWVVSATEELQPCAPGT 1252
+ + ++P GG + +G Y W + E+ +P GT
Sbjct: 1676 PLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYW---SREDGRPVPSGT 1722
Score = 64.7 bits (156), Expect = 1e-09
Identities = 41/125 (32%), Positives = 51/125 (40%), Gaps = 19/125 (15%)
Query: 1082 TPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNA--TGSR 1139
T PG P C C+ H+ G C CQ T G C +C+ G FG+A +
Sbjct: 750 TRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATAT 809
Query: 1140 GCRPCQCNGHGDPRRGHCDNLSGLCF-----------CQDHTEGAHCQLCSPGYYGDP-R 1187
CRPC C RR S CF C G C+ C+PGY G+P +
Sbjct: 810 SCRPCPCPYIDASRR-----FSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQ 864
Query: 1188 AGGSC 1192
GG C
Sbjct: 865 PGGKC 869
Score = 60.5 bits (145), Expect = 2e-08
Identities = 54/210 (25%), Positives = 75/210 (35%), Gaps = 58/210 (27%)
Query: 2162 NGSCVEPDHCRCHFGFVGRNCST------------------ECRCNRH-SECAGVGARDH 2202
+G + CRC G+ G +C + C CN H S C V H
Sbjct: 722 HGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYG--H 779
Query: 2203 CLLCRNHTKGSHCEQCLPLFVGSAV--GGGTCRPCHAFCRGNSHICISRKELQMSKGEPK 2260
CL C+++T+G C +C F G A+ +CRPC + S+
Sbjct: 780 CLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPC------------PYIDASRRFSD 827
Query: 2261 KYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGY----FLLDGKCTKCQCN 2316
LD ++ +A C C G +CESC GY GKC N
Sbjct: 828 TCFLD------------TDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCR--PVN 873
Query: 2317 GHADTCNEQ-----DGTGCPCQNNTETGTC 2341
C+E+ G C C+NN C
Sbjct: 874 QEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Score = 60.5 bits (145), Expect = 2e-08
Identities = 51/162 (31%), Positives = 65/162 (40%), Gaps = 29/162 (17%)
Query: 1121 GEHCERCRPGSFGNATGSR--GCRPCQCNGHGD---PRRGHCDNLSGLCFCQDHTEGAHC 1175
G C+ C PG +G C C+CNGH D P G C CQ + G C
Sbjct: 1538 GLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQ------CQHNAAGEFC 1591
Query: 1176 QLCSPGYYGDPRAGGSCFRECGGRAL-LTN--------VSSVALGSRRVGGLLP--PGGG 1224
+LC+PGYYGD AG +C A LTN S+ G R P G
Sbjct: 1592 ELCAPGYYGDATAGTP--EDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQY 1649
Query: 1225 AARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSS 1266
+ GPG +V + + + C P T PL + P S
Sbjct: 1650 CEQCGPG-----YVGNPSVQGGQCLPETNQAPLVVEVHPARS 1686
Score = 60.1 bits (144), Expect = 3e-08
Identities = 54/192 (28%), Positives = 68/192 (35%), Gaps = 44/192 (22%)
Query: 1032 ECHCQRGYQGDGISHCNR------------TCLEDC---GH--------GVCSGPPDFT- 1067
+C C GY+G C+ TC E C GH G C G T
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTC-ERCSCHGHSEACEPETGACQGCQHHTE 1183
Query: 1068 ---CV-CDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHC---RKRGPGFCDECQDWTW 1120
C C G+ D TP P C D +H G CD C
Sbjct: 1184 GPRCEQCQPGYYGDAQRGTPQDCQLCP-CYGDPAAGQAAHTCFLDTDGHPTCDACSPGHS 1242
Query: 1121 GEHCERCRPGSFGNATGSRGCRP---------CQCNGHGDPRRGHCDNLSGLCFCQDHTE 1171
G HCERC PG +GN + + C+ C C+ G CD +G C C+ E
Sbjct: 1243 GRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVS-SQCD-AAGQCQCKAQVE 1300
Query: 1172 GAHCQLCSPGYY 1183
G C C P ++
Sbjct: 1301 GLTCSHCRPHHF 1312
Score = 56.2 bits (134), Expect = 4e-07
Identities = 110/488 (22%), Positives = 145/488 (29%), Gaps = 136/488 (27%)
Query: 1032 ECHCQRGYQGDGISHCNRTCLEDCGH---GVCSGPPDFTCVCDLGWTSDLPP-------- 1080
EC C GY G C+ G G CSG C C+ G S P
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSG-----CNCN-GHASSCDPVYGHCLNC 783
Query: 1081 PTPAPGPPAPRCS---------------RDCGCSFHSHCRK---------RGPGFCDECQ 1116
GP +C R C C + R+ G CD C
Sbjct: 784 QHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACA 843
Query: 1117 DWTWGEHCERCRPGSFGNATGSRG-CRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHC 1175
G CE C PG GN G CRP RG C C+++ G C
Sbjct: 844 PGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLC 903
Query: 1176 QLCSPGYY----GDPRAGGSCF-----REC----------------GGRALLTNVSSV-- 1208
C+ G + +P CF R C G LTN +S
Sbjct: 904 NECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTNAASTHT 963
Query: 1209 ----------------------------ALGSRRVGGLLPPGGGAARAGPGLSYCVWVVS 1240
+L SR +G + GG R +
Sbjct: 964 TNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELR-----------FT 1012
Query: 1241 ATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFPRFLDTGVVQSDRSLIAAFC 1300
T+ QP + PL + L + +A + P T +V
Sbjct: 1013 VTQRSQPGSTPLHGQPLVVL----QGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPD 1068
Query: 1301 GQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSARCGSGGPGSCPVPQECVPQDGA 1360
GQ R + AL+G+ L A+ + +R SG VP+E QD A
Sbjct: 1069 GQPATREHLLMALAGIDTLLIRAS------YAQQPAESRV-SGISMDVAVPEE-TGQDPA 1120
Query: 1361 AGAGLCRCPQGWAGPHCR--------------MALCPENCNAHTGAGTCNQSLGVCI-CA 1405
C CP G+ GP C+ + C E C+ H + C G C C
Sbjct: 1121 LEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTC-ERCSCHGHSEACEPETGACQGCQ 1179
Query: 1406 EGFGGPDC 1413
GP C
Sbjct: 1180 HHTEGPRC 1187
Score = 53.9 bits (128), Expect = 2e-06
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 20/133 (15%)
Query: 2273 VTEGPSEDEAVCV---NCQNNSYGEKCESCLQGYF-----LLDGKCTKCQCNGHADTCNE 2324
V E +D A+ V +C G C+ C GY L G C +C C+GH++ C
Sbjct: 1111 VPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEP 1170
Query: 2325 QDGTGCPCQNNTETGTCQGSSPSDRRDCYK---YQCAKCRESFHGSPLGGQQCYRLISVE 2381
+ G CQ++TE C+ P D + C C +G P GQ +
Sbjct: 1171 ETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLC--PCYGDPAAGQAAH------ 1222
Query: 2382 QECCLDPTSQTNC 2394
C LD C
Sbjct: 1223 -TCFLDTDGHPTC 1234
Score = 53.9 bits (128), Expect = 2e-06
Identities = 60/234 (25%), Positives = 78/234 (33%), Gaps = 72/234 (30%)
Query: 2136 ECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECA 2195
+CSC GY P C Q C G + R G C C C+ HSE
Sbjct: 1125 QCSCPPGYR--------GPSC-QDCDTG------YTRTPSGLYLGTCE-RCSCHGHSEAC 1168
Query: 2196 G--VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGG--GTCRPCHAFCRGN------SHI 2245
GA C C++HT+G CEQC P + G A G C+ C C G+ +H
Sbjct: 1169 EPETGA---CQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCP--CYGDPAAGQAAHT 1223
Query: 2246 CISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFL 2305
C LD ++ C C G CE C GY+
Sbjct: 1224 CF----------------LD------------TDGHPTCDACSPGHSGRHCERCAPGYYG 1255
Query: 2306 LDGKCTKCQ------------CNGHADTCNEQDGTG-CPCQNNTETGTCQGSSP 2346
+ CQ C+ ++ D G C C+ E TC P
Sbjct: 1256 NPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRP 1309
Score = 48.5 bits (114), Expect = 9e-05
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 2287 CQNNSYGEKCESCLQGYF-----LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTC 2341
C G C+ C GY L G C C+CNGH+D C+ + G CQ+N C
Sbjct: 1532 CPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFC 1591
Query: 2342 QGSSP 2346
+ +P
Sbjct: 1592 ELCAP 1596
Score = 47.8 bits (112), Expect = 2e-04
Identities = 39/134 (29%), Positives = 47/134 (35%), Gaps = 14/134 (10%)
Query: 2269 IENWVTEGPSEDEAVCVN---CQNNSYGEKCESCLQGYFLLDG-----KCTKCQCNGHAD 2320
++ VT S A V C G CESC + + G C+ C CNGHA
Sbjct: 712 MDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHAS 771
Query: 2321 TCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSPLGGQQCYRLISV 2380
+C+ G CQ+NTE C D K CR P R S
Sbjct: 772 SCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRP----CPCPYIDASRRFS- 826
Query: 2381 EQECCLDPTSQTNC 2394
C LD Q C
Sbjct: 827 -DTCFLDTDGQATC 839
Score = 47.8 bits (112), Expect = 2e-04
Identities = 45/173 (26%), Positives = 57/173 (32%), Gaps = 49/173 (28%)
Query: 2136 ECSCKTGYTMDNMTGLCRPVCAQGCVN-GSCVEPDHCRCHFGFVGRNCSTECRCNRHSEC 2194
EC C GY GL CA G GS + HC C CN HS+
Sbjct: 1529 ECRCPPGYI-----GLSCQDCAPGYTRTGSGLYLGHCEL------------CECNGHSDL 1571
Query: 2195 AG--VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGT--CRPCHAFCRGNSHICISRK 2250
GA C C+++ G CE C P + G A G C+PC
Sbjct: 1572 CHPETGA---CSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLT---------- 1618
Query: 2251 ELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGY 2303
+PE + + E C C+ G+ CE C GY
Sbjct: 1619 --------------NPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGY 1657
Score = 41.2 bits (95), Expect = 0.014
Identities = 38/159 (23%), Positives = 52/159 (32%), Gaps = 53/159 (33%)
Query: 2212 GSHCEQCLPLFV--GSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEI 2269
G C+ C P + GS + G C C C G+S +C
Sbjct: 1538 GLSCQDCAPGYTRTGSGLYLGHCELCE--CNGHSDLC----------------------- 1572
Query: 2270 ENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTG 2329
+ C CQ+N+ GE CE C GY+ G T A T +
Sbjct: 1573 --------HPETGACSQCQHNAAGEFCELCAPGYY---GDAT-------AGTPEDCQPCA 1614
Query: 2330 CPCQN--NTETGTCQGSSPSDRRDCYKYQCAKCRESFHG 2366
CP N N + TC+ Y+C C + G
Sbjct: 1615 CPLTNPENMFSRTCESLGAGG------YRCTACEPGYTG 1647
Score = 40.0 bits (92), Expect = 0.032
Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 16/122 (13%)
Query: 2114 ECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRC 2173
EC NGH D CH P CS LC P G+ + C C
Sbjct: 1564 EC-NGHSDL-----CH--PETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCAC 1615
Query: 2174 HFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGS-AVGGGTC 2232
+ E +R E G G C C G +CEQC P +VG+ +V GG C
Sbjct: 1616 PL------TNPENMFSRTCESLGAGGY-RCTACEPGYTGQYCEQCGPGYVGNPSVQGGQC 1668
Query: 2233 RP 2234
P
Sbjct: 1669 LP 1670
Score = 39.7 bits (91), Expect = 0.042
Identities = 44/147 (29%), Positives = 51/147 (34%), Gaps = 40/147 (27%)
Query: 1035 CQRGYQGDGISHCNRTCLEDCGHGVCSGPPD-----FTCVCDLGW--TSDLPPP------ 1081
CQ GY GD R +DC C G P TC D T D P
Sbjct: 1190 CQPGYYGDA----QRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRH 1245
Query: 1082 ----------TPAPGPPAPRCSR-----DCGC----SFHSHCRKRGPGFCDECQDWTWGE 1122
P+ G P R S+ C C S S C G C +C+ G
Sbjct: 1246 CERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQ--C-QCKAQVEGL 1302
Query: 1123 HCERCRPGSFG-NATGSRGCRPCQCNG 1148
C CRP F +A+ GC PC C G
Sbjct: 1303 TCSHCRPHHFHLSASNPDGCLPCFCMG 1329
Score = 37.4 bits (85), Expect = 0.21
Identities = 31/115 (26%), Positives = 42/115 (36%), Gaps = 22/115 (19%)
Query: 987 GEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNT-PLSYECHCQRGYQGDGIS 1045
G+ L L + +C D C C ATC+ ++C C+ G++GD
Sbjct: 4084 GKRLDLTYSFLGSQGIGQCYDSSPCER--QPCQHGATCMPAGEYEFQCLCRDGFKGDLCE 4141
Query: 1046 HCNRTC--LEDCGH-GVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCG 1097
H C E C H G C G C+C PG PRC + G
Sbjct: 4142 HEENPCQLREPCLHGGTCQGT---RCLC-------------LPGFSGPRCQQGSG 4180
Score = 36.6 bits (83), Expect = 0.35
Identities = 40/153 (26%), Positives = 53/153 (34%), Gaps = 15/153 (9%)
Query: 91 GDSPRGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFN--ASFRFSLCPGGCQS 148
G P+ L + G R I+ +F D N G + + R C G Q
Sbjct: 3805 GAIPKAGLSSGFIGCVRELRIQGEE-----IVFHDLNLTAHGISHCPTCRDRPCQNGGQC 3859
Query: 149 HGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGRACDLHLWE 208
H VC C G+ G C E S H P C P G C HL
Sbjct: 3860 HDSESSSYVCVCPAGFTGSRC---EHSQALHCHPEACGPDATCVNRPDGRGYTCRCHLGR 3916
Query: 209 NQGAGWWHNVSARDPAFSARIGAAGAFLSPPGL 241
+ G V+ P+ S AG++L+ P L
Sbjct: 3917 S-GLRCEEGVTVTTPSLS----GAGSYLALPAL 3944
Score = 36.2 bits (82), Expect = 0.46
Identities = 36/125 (28%), Positives = 47/125 (37%), Gaps = 24/125 (19%)
Query: 146 CQSHGQCQPPGV----CACEPGWGGPDCGLQECSAY----CGSHGTCASPLGPCRCEPGF 197
CQ C P G C C G+ G C +E C GTC C C PGF
Sbjct: 4113 CQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTR--CLCLPGF 4170
Query: 198 LGRACDLHLWENQGAGWWHNVSARD-----PAFSARIGAAGAFLSPPGLLAVFGGQDLNN 252
G C QG+G H ++ D + G GA+ G LA F G +
Sbjct: 4171 SGPRC------QQGSG--HGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLA-FPGHVFSR 4221
Query: 253 ALGDL 257
+L ++
Sbjct: 4222 SLPEV 4226
Score = 34.7 bits (78), Expect = 1.3
Identities = 35/122 (28%), Positives = 47/122 (38%), Gaps = 19/122 (15%)
Query: 503 PEGRAAPPSGRYSHVAAVLGGSVLLVAGGYSGRPR-----GDLMAYKVPPFVFQAPAPDY 557
P+G+ P+ R + A+ G LL+ Y+ +P G M VP Q PA +
Sbjct: 1067 PDGQ---PATREHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPEETGQDPALE- 1122
Query: 558 HLDYCSMYTDHSVCSRDPECSWCQGACQAAPPPGTPLGACPAASCLGLGRL----LGDCQ 613
++ CS + R P C C P G LG C SC G G CQ
Sbjct: 1123 -VEQCSCPPGY----RGPSCQDCDTG-YTRTPSGLYLGTCERCSCHGHSEACEPETGACQ 1176
Query: 614 AC 615
C
Sbjct: 1177 GC 1178
Score = 34.3 bits (77), Expect = 1.8
Identities = 48/186 (25%), Positives = 58/186 (31%), Gaps = 37/186 (19%)
Query: 2096 TCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV 2155
TC R +C PE G E C GY + G D C
Sbjct: 1155 TCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGD 1214
Query: 2156 CAQGCVNGSC-VEPD---------------HC-RCHFGFVGRNCSTECRCNRHSECAG-- 2196
A G +C ++ D HC RC G+ G N S C R S+ G
Sbjct: 1215 PAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYG-NPSQGQPCQRDSQVPGPI 1273
Query: 2197 -------------VGARDHCLLCRNHTKGSHCEQCLP-LFVGSAVGGGTCRPCHAFCRGN 2242
A C C+ +G C C P F SA C PC FC G
Sbjct: 1274 GCNCDPQGSVSSQCDAAGQC-QCKAQVEGLTCSHCRPHHFHLSASNPDGCLPC--FCMGI 1330
Query: 2243 SHICIS 2248
+ C S
Sbjct: 1331 TQQCAS 1336
Score = 33.1 bits (74), Expect = 3.9
Identities = 23/69 (33%), Positives = 27/69 (39%), Gaps = 8/69 (11%)
Query: 2122 CNETQNCHD-QPHGYECSCKTGYT---MDNMTGL-CRP-VCAQG--CVNGSCVEPDHCRC 2173
C CHD + Y C C G+T ++ L C P C CVN CRC
Sbjct: 3853 CQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRC 3912
Query: 2174 HFGFVGRNC 2182
H G G C
Sbjct: 3913 HLGRSGLRC 3921
Score = 32.0 bits (71), Expect = 8.7
Identities = 27/86 (31%), Positives = 30/86 (34%), Gaps = 18/86 (20%)
Query: 1341 GSGGPGSCPVPQECVPQDGAAGAGL---------CRCPQGWAGPHCRMALCP----ENCN 1387
GS G G C C Q GA C C G+ G C P E C
Sbjct: 4095 GSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPC- 4153
Query: 1388 AHTGAGTCNQSLGVCICAEGFGGPDC 1413
GTC + C+C GF GP C
Sbjct: 4154 --LHGGTCQGTR--CLCLPGFSGPRC 4175
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 82.8 bits (203), Expect = 4e-15
Identities = 106/415 (25%), Positives = 145/415 (34%), Gaps = 94/415 (22%)
Query: 799 CLTSATCHLRQGGA--HC-GDDGAGGSLLVLVPTLCPLCEEHRDCHACTQDP-FCEWHQS 854
C+ C ++ GG HC +G+ +L P D C ++P C+
Sbjct: 1153 CVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHC 1212
Query: 855 TSRKGDAACSRRGRGRGALKSPEECPPLCSQRLTCED---CLANSSQCAW--CQSTHTCF 909
T+ G C G + +P+ TC D C N C C++T F
Sbjct: 1213 TNMPGGHRCLCYD---GFMATPD--------MRTCVDVDECDLNPHICLHGDCENTKGSF 1261
Query: 910 LFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCL 969
+ L G G D E +CD +C S C RCL
Sbjct: 1262 VCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC------------RCL 1309
Query: 970 QGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARCHPRATCLNTPL 1029
G WVG+G C D+DEC RC PR CLN P
Sbjct: 1310 PG-------------WVGDGF-------------ECHDLDECVSQEHRCSPRGDCLNVPG 1343
Query: 1030 SYECHCQRGYQGDGISHCNR-TCLED---CGHGVC-SGPPDFTCVCDLGWTSDLPPPTPA 1084
SY C C++G+ GDG +R C E+ C +G C + P + C C++G+ P
Sbjct: 1344 SYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFD---PTEDHR 1400
Query: 1085 PGPPAPRCSRDCGCSFHSHCRK----------------RGPGFC---DECQDWTWGEHCE 1125
C++ C+F S C RG G C +EC D
Sbjct: 1401 ACQDVDECAQGNLCAFGS-CENLPGMFRCICNGGYELDRGGGNCTDINECADPV------ 1453
Query: 1126 RCRPGSFGNATGSRGCRPCQCNGHGDPRRGHC-DNLSGLCFCQDHTEGAHCQLCS 1179
C G N GS C C + +P C D +G CF + H G CS
Sbjct: 1454 NCINGVCINTPGSYLC-SCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCS 1507
Score = 63.2 bits (152), Expect = 4e-09
Identities = 128/496 (25%), Positives = 168/496 (33%), Gaps = 136/496 (27%)
Query: 786 SCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVP--------TLCPLCEEH 837
S + C A+ G G S C L + A G+ L P TLCP E
Sbjct: 1502 SGISCSAEIGVGVTRASCCCSLGR---------AWGNPCELCPMANTTEYRTLCPGGEGF 1552
Query: 838 R---------DCHACTQDP-FCEWHQSTSRKGDAACSRRGRGRGALKSPEECPP---LCS 884
+ D C + P C+ + G C ECPP L
Sbjct: 1553 QPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQC--------------ECPPGYHLSE 1598
Query: 885 QRLTCED---CLANSSQCA--WCQST---HTCFLFAAYLARYPHGGCRGWDDSV---HSE 933
CED C +S C C +T +TC A YL C SV H
Sbjct: 1599 HTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYN 1658
Query: 934 PRCRSCDGF-LTCHECLQSHECG--W------------------CGNEDNPTL-----GR 967
C++ F +T C S+ G W CGN+ L G+
Sbjct: 1659 GTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGK 1718
Query: 968 CLQGDFSGPL----GGGNCSLWVGEGLGLPVALPARWAY----ARCPDVDECRLGLARCH 1019
L D G + G C +G PA + Y C DVDEC + C
Sbjct: 1719 PLDIDECGEIPAICANGICINQIGS---FRCECPAGFNYNSILLACEDVDECGSRESPCQ 1775
Query: 1020 PRATCLNTPLSYECHCQRGYQGDGISHC--NRTCLE---DCGHGVCSGPP-DFTCVCDLG 1073
A C+N P SY C C RGY+ C C E C HG C + C+C G
Sbjct: 1776 QNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRG 1835
Query: 1074 WTSDLPPPTPAPGPPAPRCSRD-CG---C-----SFHSHCRKRGPGFC----DECQDWTW 1120
+ + C R CG C S++ C PGF +C D+
Sbjct: 1836 FQASADQTLCM---DIDECDRQPCGNGTCKNIIGSYNCLC---FPGFVVTHNGDCVDF-- 1887
Query: 1121 GEHC-----ERCRPGSFGNATGSRGCRPCQ------CNGHGDPRRGHCDNLSGLCF---C 1166
+ C + CR G N GS C CQ +G C +L+G C C
Sbjct: 1888 -DECTTLVGQVCRFGHCLNTAGSFHCL-CQDGFELTADGKNCVDTNECLSLAGTCLPGTC 1945
Query: 1167 QDHTEGAHCQLCSPGY 1182
Q + EG+ +C PG+
Sbjct: 1946 Q-NLEGSFRCICPPGF 1960
Score = 59.3 bits (142), Expect = 5e-08
Identities = 69/241 (28%), Positives = 89/241 (36%), Gaps = 58/241 (24%)
Query: 2033 LRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPH-CG-----WCAWGGQDGGGR---- 2082
L CMAGG GR E+ G + L+ P+ CG +C G + GR
Sbjct: 23 LLCMAGGQGRWDGALEAAGPGRVRRRGSPGILQGPNVCGSRFHAYCCPGWRTFPGRSQCV 82
Query: 2083 -------CMEGGLSGPR-----DGL---TCGRPGASWAFLSCPPEDECANGHHDCNETQN 2127
C EG S P DG +CG S +SC C
Sbjct: 83 VPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTC------------ 130
Query: 2128 CHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGS-CVEPDHCRCHFGFVGRNCSTEC 2186
G C C+ GYT T +P+C +GC NG C+ P+ C C +GF+G C
Sbjct: 131 -----RGASCLCQKGYTG---TVCGQPICDRGCHNGGRCIGPNRCACVYGFMGPQCE--- 179
Query: 2187 RCNRHSECAG-VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHI 2245
R R C G VG C++ G C + L + VG PC C H
Sbjct: 180 RDYRTGPCFGQVGPEG----CQHQLTGLVCTKAL---CCATVGRAWGLPCE-LCPAQPHP 231
Query: 2246 C 2246
C
Sbjct: 232 C 232
Score = 57.8 bits (138), Expect = 1e-07
Identities = 112/457 (24%), Positives = 149/457 (32%), Gaps = 93/457 (20%)
Query: 790 CLADQGCGWCLTSATCHLRQGGAHCG-DDGAGGSLLVLVPTLCPLCEEHRDCHACTQDPF 848
C CG TC GG C DG P L CE D C+ +P
Sbjct: 2130 CSVGHPCG----QGTCTNVIGGFECACADG-------FEPGLMMTCE---DIDECSLNPL 2175
Query: 849 CEWHQSTSRKGDAACSRRG----RGRGAL-KSPEECPPLCSQRLTCEDCLANSSQCAWCQ 903
+ + +G C+ R GA+ + +EC +DC A +C
Sbjct: 2176 LCAFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECAD------GQQDCHARGMECKNLI 2229
Query: 904 STHTCFLFAAYLARYPHG-GCRGWDDSVHSEP---------------RCRSCDGFLTCHE 947
T C G GC D+ H++P RC +GF
Sbjct: 2230 GTFACVCPPGMRPLPGSGEGCTD-DNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPT 2288
Query: 948 CLQSHEC--GWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVAL---PARWAY 1002
+ H+ G C E T+ R L S + C G G G L P AY
Sbjct: 2289 LTECHDIRQGPCFAEVLQTMCRSLSSS-SEAVTRAECCCGGGRGWGPRCELCPLPGTSAY 2347
Query: 1003 AR-CP----------DVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGIS------ 1045
+ CP DVDECR+ LA C+N+ S+ CHCQ GY D +
Sbjct: 2348 RKLCPHGSGYTAEGRDVDECRM-LAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDM 2406
Query: 1046 --------HCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCG 1097
C C G +CS P + D DL T C G
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 1098 CSFHSHCRKRGPGFCDECQDWTWGEHCERCRP---GSFGNATGSRGCRPCQC-------- 1146
+F C PGF Q + C +P G+ G+ + G C+C
Sbjct: 2467 -AFTCRC---PPGFTQHHQACFDNDECS-AQPGPCGAHGHCHNTPGSFRCECHQGFTLVS 2521
Query: 1147 NGHGDPRRGHCDNLSGLCF-CQDHTEGAHCQLCSPGY 1182
+GHG CD CQ+ G C C G+
Sbjct: 2522 SGHGCEDVNECDGPHRCQHGCQNQLGGYRCS-CPQGF 2557
Score = 54.3 bits (129), Expect = 2e-06
Identities = 65/242 (26%), Positives = 87/242 (35%), Gaps = 46/242 (19%)
Query: 955 GWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLG 1014
G C + D T C GD G +C + G A P R A C DVDEC +
Sbjct: 445 GECIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQ-----ATPTRQA---CVDVDECIVS 496
Query: 1015 LARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCLED--------CGHGVCSGPP-D 1065
CH C+NT S++C C G++ +S + C++ C +GVC
Sbjct: 497 GGLCH-LGRCVNTEGSFQCVCNAGFE---LSPDGKNCVDHNECATSTMCVNGVCLNEDGS 552
Query: 1066 FTCVCDLGWTSDLPPPTPAPGPPAPRCSRDC---GCSFHSHCRKRGPGFCDECQDW---- 1118
F+C+C G+ APG +C G + HC F +C
Sbjct: 553 FSCLCKPGFLL-------APGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVG 605
Query: 1119 TWGEHC--ERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQ 1176
T G C R +G RP G + C C DH G CQ
Sbjct: 606 TDGRVCVDTHVRSTCYGAIEKGSCARPFP----GTVTKSEC-----CCANPDHGFGEPCQ 656
Query: 1177 LC 1178
LC
Sbjct: 657 LC 658
Score = 54.3 bits (129), Expect = 2e-06
Identities = 82/401 (20%), Positives = 125/401 (31%), Gaps = 96/401 (23%)
Query: 1807 PDPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSPMPRSPEECRRLRTCSE 1866
P L + AC C+ G C G + +G C +S + + +E
Sbjct: 1099 PPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINE 1158
Query: 1867 CLARHPRTLQPGDGEASTPRCKWCTNCPEGACIGRNG-SCTSENDCRINQREVFWAGNCS 1925
C ++ + RC +C +G + +G +C ++C N R
Sbjct: 1159 CRVQNGGCDVHCINTEGSYRC----SCGQGYSLMPDGRACADVDECEENPR--------- 1205
Query: 1926 EAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESS 1985
C C +C+ F T + R + V
Sbjct: 1206 --VCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDE---------------------- 1241
Query: 1986 PPLPCPTPCHLLPNCTSCLDSKGADGGWQ-HCVWSSSLQQCLSPSYLPLRCMAGGCGRLL 2044
C L P+ D + G + HC Y+ +R A GC +
Sbjct: 1242 --------CDLNPHICLHGDCENTKGSFVCHC----------QLGYM-VRKGATGCSDV- 1281
Query: 2045 RGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASW 2104
+ C +G A CL P C RC+ G + DG
Sbjct: 1282 ---DECEVGGHNCDSHASCLNIPGSFSC---------RCLPGWVG---DGF--------- 1317
Query: 2105 AFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQG---CV 2161
C DEC + H C+ +C + P Y C+C+ G+ D R CA+ C
Sbjct: 1318 ---ECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD 1374
Query: 2162 NGSCVEPD---HCRCHFGF----VGRNCSTECRCNRHSECA 2195
NG C+ C C GF R C C + + CA
Sbjct: 1375 NGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCA 1415
Score = 53.9 bits (128), Expect = 2e-06
Identities = 66/249 (26%), Positives = 90/249 (36%), Gaps = 50/249 (20%)
Query: 959 NEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAYARCPDVDECRLGLARC 1018
NE G C G +G +C+ G AL A+ C D+DECR+ C
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGG------FALDAQ--ERNCTDIDECRISPDLC 1039
Query: 1019 HPRATCLNTPLSYECHCQRGYQGD--------GISHCNR--------TCLEDCGHGVCSG 1062
+ TC+NTP S+EC C GY+ + C R TC G C
Sbjct: 1040 G-QGTCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQC 1098
Query: 1063 PPDFTCVCDLGWTSDLPPPTPAPG-PPAPRCSR-------DCGCSFHSHCRKRGPGFCDE 1114
PP D+ + + G P +C C F S ++G +E
Sbjct: 1099 PPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINE 1158
Query: 1115 CQDWTWG--EHC------ERCRPG-SFGNATGSRGCRPC-QCNGHGDPR---RGHCDNLS 1161
C+ G HC RC G + R C +C +PR +GHC N+
Sbjct: 1159 CRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDEC--EENPRVCDQGHCTNMP 1216
Query: 1162 G--LCFCQD 1168
G C C D
Sbjct: 1217 GGHRCLCYD 1225
Score = 53.9 bits (128), Expect = 2e-06
Identities = 41/165 (24%), Positives = 66/165 (40%), Gaps = 18/165 (10%)
Query: 2107 LSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLC--RPVCAQ---GCV 2161
L+C DEC + C + +C + P Y C C GY + + G C R C + C
Sbjct: 1759 LACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNECREIPNVCS 1817
Query: 2162 NGSCVEPD---HCRCHFGFVGRNCSTEC----RCNR----HSECAGVGARDHCLLCRNHT 2210
+G C++ + C CH GF T C C+R + C + +C LC
Sbjct: 1818 HGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSYNC-LCFPGF 1876
Query: 2211 KGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMS 2255
+H C+ + + G CR H S C+ + +++
Sbjct: 1877 VVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELT 1921
Score = 52.4 bits (124), Expect = 6e-06
Identities = 82/337 (24%), Positives = 112/337 (33%), Gaps = 73/337 (21%)
Query: 2108 SCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGY--TMDNMTGLCRPVCAQG---CVN 2162
+C DEC C++ +C + P G+ C C G+ T D T + C C++
Sbjct: 1193 ACADVDECEENPRVCDQG-HCTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLH 1251
Query: 2163 GSCVEPDH---CRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL 2219
G C C C G++ R +T C E G H C N GS +CL
Sbjct: 1252 GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHA-SCLN-IPGSFSCRCL 1309
Query: 2220 PLFVGSAVGGGTCRPCHAF--CRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGP 2277
P +VG CH C H C R + G + + + E
Sbjct: 1310 PGWVGDGF------ECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDR 1363
Query: 2278 ---SEDEAVCVN--CQNNSYGEKCE------------------SCLQGYFLLDGKCT--- 2311
+E+ +C N C N G +CE C QG G C
Sbjct: 1364 DECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLP 1423
Query: 2312 ---KCQCNGHADT----CNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESF 2364
+C CNG + N D C N G C + S Y C+ C + F
Sbjct: 1424 GMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGS-------YLCS-CPQDF 1475
Query: 2365 HGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRR 2401
+P G C+D T NCF E R
Sbjct: 1476 ELNPSG------------VGCVD-TRAGNCFLETHDR 1499
Score = 48.9 bits (115), Expect = 7e-05
Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 20/156 (12%)
Query: 2100 PGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV---- 2155
PG + +C DEC+ C +CH+ P + C C G+T+ + C V
Sbjct: 2474 PGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECD 2533
Query: 2156 ----CAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTK 2211
C GC N + C C GF S +C +ECA CRN
Sbjct: 2534 GPHRCQHGCQNQ--LGGYRCSCPQGFTQH--SQWAQCVDENECALSPPTCGSASCRNTLG 2589
Query: 2212 GSHCEQCLPLFVGSAVGG--------GTCRPCHAFC 2239
G C A+GG G PC C
Sbjct: 2590 GFRCVCPSGFDFDQALGGCQEVDECAGRRGPCSYSC 2625
Score = 47.8 bits (112), Expect = 2e-04
Identities = 66/291 (22%), Positives = 89/291 (30%), Gaps = 79/291 (27%)
Query: 2115 CANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCH 2174
C NG C P Y C C GYT D V G C++ D C
Sbjct: 419 CLNGR--------CLPTPSSYRCECNVGYTQD--------------VRGECIDVDEC--- 453
Query: 2175 FGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRP 2234
S+ C H +C + HC C + + Q V GG C
Sbjct: 454 -------TSSPC---HHGDCVNIPGTYHC-RCYPGFQATPTRQACVDVDECIVSGGLCHL 502
Query: 2235 CHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVN--CQNNSY 2292
S C+ ++S + +N V +CVN C N
Sbjct: 503 GRCVNTEGSFQCVCNAGFELS-----------PDGKNCVDHNECATSTMCVNGVCLNEDG 551
Query: 2293 GEKCESCLQGYFLLDG-----KCTKCQ-----CNGHADTCNEQDGT-GCPCQNNTETGTC 2341
C C G+ L G +CQ NGH C +G+ C C GT
Sbjct: 552 SFSC-LCKPGFLLAPGGHYCMDIDECQTPGICVNGH---CTNTEGSFRCQCLGGLAVGT- 606
Query: 2342 QGSSPSD---RRDCY-KYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDP 2388
G D R CY + C F G+ ++ + CC +P
Sbjct: 607 DGRVCVDTHVRSTCYGAIEKGSCARPFPGT----------VTKSECCCANP 647
Score = 47.8 bits (112), Expect = 2e-04
Identities = 55/208 (26%), Positives = 64/208 (30%), Gaps = 52/208 (25%)
Query: 1005 CPDVDECRLGLARCHPRATCLNTPLSYECHCQRGY-------------QGDGISHCNRTC 1051
C D DEC C C NTP S+ C C +G+ + DG C C
Sbjct: 2483 CFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGC 2542
Query: 1052 LEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGF 1111
G CS P FT W + A PP CG + CR GF
Sbjct: 2543 QNQLGGYRCSCPQGFTQHSQ--WAQCVDENECALSPPT------CG---SASCRNTLGGF 2591
Query: 1112 CDECQDWTWGEHCERCRPGSFGNATGSRGCRPC-QCNGHGDPRRGHCDNLSGLCFCQDHT 1170
C P F GC+ +C G P C N G C
Sbjct: 2592 RCVC-------------PSGFDFDQALGGCQEVDECAGRRGPCSYSCANTPGGFLCG--- 2635
Query: 1171 EGAHCQLCSPGYYGDPRAG-GSCFRECG 1197
C GY+ RAG G C G
Sbjct: 2636 -------CPQGYF---RAGQGHCVSGLG 2653
Score = 46.2 bits (108), Expect = 4e-04
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQE---CSAYCGSHGTCASPLGPCRCEPGF 197
+C C G C P +C C G P CG+ CS C + GTC C C+ G+
Sbjct: 85 ICRRAC-GEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRG--ASCLCQKGY 141
Query: 198 LGRAC 202
G C
Sbjct: 142 TGTVC 146
Score = 45.8 bits (107), Expect = 6e-04
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 2/66 (3%)
Query: 138 RFSLCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGF 197
R S C C + G C+ C C+ G+ G CG C C + G C P C C GF
Sbjct: 116 RGSGCSVSCMNGGTCRGAS-CLCQKGYTGTVCGQPICDRGCHNGGRCIGP-NRCACVYGF 173
Query: 198 LGRACD 203
+G C+
Sbjct: 174 MGPQCE 179
Score = 45.8 bits (107), Expect = 6e-04
Identities = 100/450 (22%), Positives = 131/450 (29%), Gaps = 103/450 (22%)
Query: 777 RSSSCTSYSSCLGCLADQGCGWCLTSATCHLRQGGAHCGDDGAGGSLLVLVPTLCPLCEE 836
R S C + C+ G C + L GGA G + +P +C
Sbjct: 1770 RESPCQQNADCINI---PGSYRCKCTRGYKLSPGGACVGRNECRE-----IPNVC----S 1817
Query: 837 HRDCHACTQDPFCEWHQSTSRKGDAA-------CSRRGRGRGALKSPEECPPLCSQRLTC 889
H DC C H+ D C R+ G G C +
Sbjct: 1818 HGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGT----------CKNIIGS 1867
Query: 890 EDCLANSSQCAW----CQSTHTCFLFAAYLARYPHGGCRGWDDSVHSEPRCRSCDGF-LT 944
+CL C C + R+ H C S H C DGF LT
Sbjct: 1868 YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGH--CLNTAGSFH----CLCQDGFELT 1921
Query: 945 CH--ECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPARWAY 1002
C+ ++EC G CL G G C + P
Sbjct: 1922 ADGKNCVDTNEC-------LSLAGTCLPGTCQNLEGSFRC-----------ICPPGFQVQ 1963
Query: 1003 A-RCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGY-QGDGISHCNRT----CLEDCG 1056
+ C D+DEC C TC N+P S++C C G+ D C T C
Sbjct: 1964 SDHCIDIDECSEEPNLCL-FGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFE 2022
Query: 1057 HGVCSGPPDFT-----CVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCR------ 1105
G CS P F C C P G P C ++ +F C
Sbjct: 2023 AGKCSVPKAFNTTKTRCCCS-------KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAV 2075
Query: 1106 -------------KRGPGFCDE--CQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHG 1150
PG C C + CE C G + TG +C+
Sbjct: 2076 PGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCE-CPFGYSLDFTGINCVDTDECSVGH 2134
Query: 1151 DPRRGHCDNLSG--LCFCQDHTEGAHCQLC 1178
+G C N+ G C C D E C
Sbjct: 2135 PCGQGTCTNVIGGFECACADGFEPGLMMTC 2164
Score = 43.5 bits (101), Expect = 0.003
Identities = 108/487 (22%), Positives = 151/487 (31%), Gaps = 111/487 (22%)
Query: 838 RDCHACTQDP-FCEWHQSTSRKGDAAC-SRRGRGRGALKSPEECPPLCSQRLTCEDCLAN 895
RD + C DP C + +G C G GA S ++C + ++C N
Sbjct: 681 RDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGA--SGKDCTDV-------DECALN 731
Query: 896 SSQC--AWCQST---HTCFLFAAYLARYPHGGCRGWDDSVHS---EPRCRSCDGFLTCHE 947
S C WCQ++ ++C + C+ D+ + S CR+ G TC
Sbjct: 732 SLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTC-- 789
Query: 948 CLQSHECGWCGNED-------NPTLGRC--------LQGDFSGPLGGGNCSLWVGEGLGL 992
+CG D + T G C + + G C +G G
Sbjct: 790 -----KCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGS 844
Query: 993 PVALP----------ARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGD 1042
P AR C DV+EC C P C+NT S+ C C G D
Sbjct: 845 PCERCEIDPACARGFARMTGVTCDDVNECESFPGVC-PNGRCVNTAGSFRCECPEGLMLD 903
Query: 1043 GISHCNRTCL-------------EDCGHGVCSGPPDFTCVCDLG--WTSDLPP-PTPAPG 1086
R C+ ++CG + C C +G W + P P
Sbjct: 904 A---SGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESL 960
Query: 1087 PPAPRCSRDCGCSFHSHCRKRG-----------PGFCDE--CQDWTWGEHCERCRPGSFG 1133
A C R G + R PG C C++ HC G F
Sbjct: 961 EFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHC--ACAGGFA 1018
Query: 1134 NATGSRGCRPC-QCNGHGD-PRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGS 1191
R C +C D +G C N G C+ C PGY +
Sbjct: 1019 LDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECE----------CFPGYESGFMLMKN 1068
Query: 1192 CF--RECGGRALLTNVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCA 1249
C EC LL + PPG G +A E++ C+
Sbjct: 1069 CMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKG----------TACEDIDECS 1118
Query: 1250 -PGTLCP 1255
LCP
Sbjct: 1119 LSDGLCP 1125
Score = 43.1 bits (100), Expect = 0.004
Identities = 94/388 (24%), Positives = 125/388 (32%), Gaps = 97/388 (25%)
Query: 2040 CGRLLRGP---ESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLT 2096
C + +GP E C + + + R C C GG+ G RC
Sbjct: 2292 CHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAEC--CCGGGRGWGPRCE-----------L 2338
Query: 2097 CGRPGASWAFLSCP----------PEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMD 2146
C PG S CP DEC H C + C + + C C+ GYT D
Sbjct: 2339 CPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGE-CINSLGSFRCHCQAGYTPD 2397
Query: 2147 NMTGLCRPV---------CAQGCVN--GSCVEPDHCRCHFGFV----GRNCS--TECRCN 2189
C + C C N GS + C C G++ GR C EC
Sbjct: 2398 ATATTCLDMDECSQVPKPCTFLCKNTKGSFL----CSCPRGYLLEEDGRTCKDLDECTSR 2453
Query: 2190 RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFV---GSAVGGGTCRPCHAFCRGNSHIC 2246
+H+ C LC N T G+ +C P F + C C + H
Sbjct: 2454 QHN-CQ--------FLCVN-TVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGH-- 2501
Query: 2247 ISRKELQMSKGEPKKYSLDPEEIENWVTEGPS-EDEAVC-------VNCQNNSYGEKCES 2298
P + + + V+ G ED C CQN G +C S
Sbjct: 2502 --------CHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRC-S 2552
Query: 2299 CLQGYFLLDGKCTKC----QCNGHADTC------NEQDGTGCPCQNNTE----TGTCQG- 2343
C QG F + +C +C TC N G C C + + G CQ
Sbjct: 2553 CPQG-FTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQEV 2611
Query: 2344 SSPSDRRDCYKYQCAKCRESF-HGSPLG 2370
+ RR Y CA F G P G
Sbjct: 2612 DECAGRRGPCSYSCANTPGGFLCGCPQG 2639
Score = 42.4 bits (98), Expect = 0.006
Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 20/129 (15%)
Query: 2109 CPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV---CAQGCVNGSC 2165
C DECA C+ C + P Y CSC G+ T +C+ V + CV+G C
Sbjct: 722 CTDVDECALNSLLCDNGW-CQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVC 780
Query: 2166 ---VEPDHCRCHFGF----VGRNC--STECRC---NRHSEC----AGVGARDHCLLCRNH 2209
C+C G G C ST+ C + S C G R C
Sbjct: 781 RNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGA 840
Query: 2210 TKGSHCEQC 2218
GS CE+C
Sbjct: 841 AWGSPCERC 849
Score = 42.0 bits (97), Expect = 0.008
Identities = 52/194 (26%), Positives = 60/194 (30%), Gaps = 39/194 (20%)
Query: 1008 VDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHC---NRTCLEDCGHGVCSG-P 1063
+D CR C CL TP SY C C GY D C + C HG C P
Sbjct: 409 IDICRHFTNLCL-NGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIP 467
Query: 1064 PDFTCVCDLGWTSDLPPPTPAPGPPAPRC-----------------SRDCGCSFHSHCRK 1106
+ C C G+ + PT C S C C+
Sbjct: 468 GTYHCRCYPGFQA---TPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSP 524
Query: 1107 RGPGFCD--ECQDWTW----------GEHCERCRPGSFGNATGSRGCRPC-QCNGHGDPR 1153
G D EC T G C+PG F A G C +C G
Sbjct: 525 DGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPG-FLLAPGGHYCMDIDECQTPGICV 583
Query: 1154 RGHCDNLSGLCFCQ 1167
GHC N G CQ
Sbjct: 584 NGHCTNTEGSFRCQ 597
Score = 41.2 bits (95), Expect = 0.014
Identities = 132/602 (21%), Positives = 188/602 (31%), Gaps = 113/602 (18%)
Query: 1808 DPCRLLSSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSP-MPRSPEECRRLRTCSE 1866
D L + + C + C G CL G + G C P + C + CSE
Sbjct: 1916 DGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSE 1975
Query: 1867 CLARHPRTLQPGDGEASTPRCKWCTNCPEG-ACIGRNGSCTSENDCR-INQREVFWAGNC 1924
E + CTN P C+ G S+N R + R+ F
Sbjct: 1976 --------------EPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF 2021
Query: 1925 SEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPT--YDWTC-FSHSLLNVSPMP 1981
C T+ C R + G+ + + + + C F H + P P
Sbjct: 2022 EAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAV---PGP 2078
Query: 1982 VESSPPLPCPTPCHLLPN-CTS--CLDSKGADGGWQ-HCVWSSSLQ----QCLSPSYLPL 2033
+S + C P CT+ C+++ DG ++ C + SL C+ +
Sbjct: 2079 DDSREDV---NECAENPGVCTNGVCVNT---DGSFRCECPFGYSLDFTGINCVDTDECSV 2132
Query: 2034 R--CMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRC--MEGG-L 2088
C G C ++ G E CA + L + C+ RC EG L
Sbjct: 2133 GHPCGQGTCTNVIGGFECA---CADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYL 2189
Query: 2089 SGPRDGLTCGRPGASWAFLSCPPEDECANGHHDCN-ETQNCHDQPHGYECSCKTGYTMDN 2147
G T GA C DECA+G DC+ C + + C C G
Sbjct: 2190 CTCPAGYTLREDGAM-----CRDVDECADGQQDCHARGMECKNLIGTFACVCPPG----- 2239
Query: 2148 MTGLCRPVCAQG---------------CVNGSCVEPD---HCRCHFGFVGRNCSTECR-- 2187
RP+ G CVNG CV C C GF TEC
Sbjct: 2240 ----MRPLPGSGEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDI 2295
Query: 2188 -------------CNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRP 2234
C S + R C G CE C PL G++ C
Sbjct: 2296 RQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELC-PL-PGTSAYRKLCPH 2353
Query: 2235 CHAF---------CRGNSHICISRKELQMSKGE-----PKKYSLDPEEIENWVTEGPSED 2280
+ CR +H+C + E S G Y+ D + S+
Sbjct: 2354 GSGYTAEGRDVDECRMLAHLC-AHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQV 2412
Query: 2281 EAVCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGT 2340
C N+ G SC +GY L + T C + + Q C N T
Sbjct: 2413 PKPCTFLCKNTKGSFLCSCPRGYLLEEDGRT---CKDLDECTSRQHNCQFLCVNTVGAFT 2469
Query: 2341 CQ 2342
C+
Sbjct: 2470 CR 2471
Score = 40.8 bits (94), Expect = 0.019
Identities = 128/596 (21%), Positives = 187/596 (31%), Gaps = 122/596 (20%)
Query: 1814 SSPEACNQSGACTWCHGACLSGDQAHRLGCGGSPCSP---MPRSPEECRRLRTC--SECL 1868
+S + C C C +G + G C P + E C+ + C S C+
Sbjct: 717 ASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPCV 776
Query: 1869 ARHPRTL------QPGDGEASTPRCKWCTNCPEGACIGRNGSCTSENDCRINQREVFWAG 1922
+ R L + G G P +C + +G C + E+ C +N +
Sbjct: 777 SGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLK----IQESRCEVNLQGASLRS 832
Query: 1923 NCSEAACGAA---DCEQCTREGKCMWTRQFKR-TGETRRILSVQPTYDWTCFSHSLLNVS 1978
C A GAA CE+C + C R F R TG T ++ ++ C + +N +
Sbjct: 833 ECC-ATLGAAWGSPCERCEIDPAC--ARGFARMTGVTCDDVNECESFPGVCPNGRCVNTA 889
Query: 1979 PMPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAG 2038
S CP L + C+D + L+ C LR
Sbjct: 890 -----GSFRCECPEGLMLDASGRLCVDVR--------------LEPCF------LRWDED 924
Query: 2039 GCGRLLRGPES-----CSLGCAQATQCALC----------LRRPHCGWCAWGGQDGG--- 2080
CG L G CS+G +C C L G+ + G
Sbjct: 925 ECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFY 984
Query: 2081 ----------GRCMEGGLSGPRDGLTCGRPGA---SWAFLSCPPEDECANGHHDCNETQN 2127
G C G C G +C DEC C +
Sbjct: 985 KDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG-T 1043
Query: 2128 CHDQPHGYECSCKTGYTMDNM-TGLCRPV--CAQG---CVNGSCVEPD---HCRCHFGF- 2177
C + P +EC C GY M C V CA+ C G+C D C+C G
Sbjct: 1044 CVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHE 1103
Query: 2178 ---VGRNCSTECRCN------RHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVG 2228
G C C+ H +C V C + C+ +
Sbjct: 1104 LTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDI------- 1156
Query: 2229 GGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVC--VN 2286
CR + C + H + + S G+ YSL P+ + E+ VC +
Sbjct: 1157 -NECRVQNGGC--DVHCINTEGSYRCSCGQ--GYSLMPDGRACADVDECEENPRVCDQGH 1211
Query: 2287 CQNNSYGEKCESCLQGYFLLDGKCT-----KCQCNG----HADTCNEQDGTGCPCQ 2333
C N G +C C G+ T +C N H D N + C CQ
Sbjct: 1212 CTNMPGGHRC-LCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQ 1266
Score = 40.4 bits (93), Expect = 0.025
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 6/62 (9%)
Query: 141 LCPGGCQSHGQCQPPGVCACEPGWGGPDCGLQECSAYCGSHGTCASPLGPCRCEPGFLGR 200
+C GC + G+C P CAC G+ GP C + G C +GP C+ G
Sbjct: 150 ICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRT------GPCFGQVGPEGCQHQLTGL 203
Query: 201 AC 202
C
Sbjct: 204 VC 205
Score = 40.0 bits (92), Expect = 0.032
Identities = 48/173 (27%), Positives = 60/173 (34%), Gaps = 35/173 (20%)
Query: 1984 SSPPLPCPTP--CHLLPNCTSCLDSKGAD--GGWQHCVWSSSLQQCLSPSYLPLRCMAGG 2039
S+ P PC CH P C +G C + +C P RC G
Sbjct: 2490 SAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC---EDVNECDGPH----RCQHG- 2541
Query: 2040 CGRLLRGPE-SCSLGCAQATQCALC-------LRRPHCGWCAWGGQDGGGRCM-EGGLSG 2090
C L G SC G Q +Q A C L P CG + GG RC+ G
Sbjct: 2542 CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDF 2601
Query: 2091 PRDGLTCGRPGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGY 2143
+ A C DECA C+ +C + P G+ C C GY
Sbjct: 2602 DQ------------ALGGCQEVDECAGRRGPCS--YSCANTPGGFLCGCPQGY 2640
Score = 39.3 bits (90), Expect = 0.055
Identities = 65/236 (27%), Positives = 82/236 (34%), Gaps = 33/236 (13%)
Query: 1998 PNCTSCLD-----SKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSL 2052
PN +C D S G G V + C S L C G G + G C
Sbjct: 98 PNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCL---CQKGYTGTVC-GQPICDR 153
Query: 2053 GCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAF--LSCP 2110
GC +C P+ C +G G +C +GP G G G L C
Sbjct: 154 GCHNGGRCI----GPNRCACVYGFM--GPQCERDYRTGPCFGQV-GPEGCQHQLTGLVCT 206
Query: 2111 PEDECAN-GHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPV----CAQG-CVNGS 2164
CA G + C QPH C+ G+ + TG C+ V G C GS
Sbjct: 207 KALCCATVGRAWGLPCELCPAQPH----PCRRGFIPNIHTGACQDVDECQAVPGLCQGGS 262
Query: 2165 CVE---PDHCRCHFGFVGRNCSTECRCNRHSECAGV--GARDHCLLCRNHTKGSHC 2215
CV HCRC G + S C R C V G R L ++T+ C
Sbjct: 263 CVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCC 318
Score = 38.5 bits (88), Expect = 0.093
Identities = 80/380 (21%), Positives = 119/380 (31%), Gaps = 91/380 (23%)
Query: 1886 RCKWCTN----CPEGACIGRN-----GSCTSENDCRINQREVFWAGNCSEAACGAADCEQ 1936
RCK CT P GAC+GRN + S DC E + C +AD
Sbjct: 1788 RCK-CTRGYKLSPGGACVGRNECREIPNVCSHGDCM--DTEGSYMCLCHRGFQASADQTL 1844
Query: 1937 CTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLNVSPMPVESSPPLPCPTPCHL 1996
C +C RQ G + I+ +Y+ CF ++ + C
Sbjct: 1845 CMDIDEC--DRQPCGNGTCKNIIG---SYNCLCFPGFVVTHN-------------GDCVD 1886
Query: 1997 LPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQ 2056
CT+ + G + HC+ ++ CL L + C
Sbjct: 1887 FDECTTLV---GQVCRFGHCLNTAGSFHCLCQDGFEL--------------TADGKNCVD 1929
Query: 2057 ATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGRPGASWAFLSCPPEDECA 2116
+C G C+ G TC S+ + CPP +
Sbjct: 1930 TNECLSL----------------AGTCLPG---------TCQNLEGSFRCI-CPPGFQVQ 1963
Query: 2117 NGH----HDCNETQN------CHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCV 2166
+ H +C+E N C + P ++C C G+ + + C C +
Sbjct: 1964 SDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF--TRF 2021
Query: 2167 EPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSA 2226
E C F T C C++ G G D C LC + E C P G+
Sbjct: 2022 EAGKCSVPKAF--NTTKTRCCCSKR---PGEGWGDPCELCPQEGSAAFQELC-PFGHGAV 2075
Query: 2227 VGGGTCRPCHAFCRGNSHIC 2246
G R C N +C
Sbjct: 2076 PGPDDSREDVNECAENPGVC 2095
Score = 38.1 bits (87), Expect = 0.12
Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 7/74 (9%)
Query: 1340 CGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSL 1399
CG C V C+ GA C C +G+ G C +C C H G +
Sbjct: 112 CGVSRGSGCSV--SCMNGGTCRGAS-CLCQKGYTGTVCGQPICDRGC--HNGGRCIGPNR 166
Query: 1400 GVCICAEGFGGPDC 1413
C C GF GP C
Sbjct: 167 --CACVYGFMGPQC 178
Score = 35.4 bits (80), Expect = 0.79
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 13/70 (18%)
Query: 149 HGQCQPPG---VCACEPGW----GGPDCG-LQECSA---YCGSHGTCASPLGP--CRCEP 195
HG C+ VC C+ G+ G C + EC C SH +C + G CRC P
Sbjct: 1251 HGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLP 1310
Query: 196 GFLGRACDLH 205
G++G + H
Sbjct: 1311 GWVGDGFECH 1320
Score = 34.3 bits (77), Expect = 1.8
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 22/115 (19%)
Query: 1317 LVLHWEA-----NGSSSW-GFNASVGSARCGS-GGPGSCPVPQECVPQDGAAGAGLCRCP 1369
L+L W A G W G + G R G PG P C G+ C CP
Sbjct: 16 LLLAWSALLCMAGGQGRWDGALEAAGPGRVRRRGSPGILQGPNVC----GSRFHAYC-CP 70
Query: 1370 QGW----AGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGG 1420
GW C + +C C G G C+Q +C CA+G P C G
Sbjct: 71 -GWRTFPGRSQCVVPICRRAC----GEGFCSQP-NLCTCADGTLAPSCGVSRGSG 119
Score = 33.5 bits (75), Expect = 3.0
Identities = 49/164 (29%), Positives = 56/164 (34%), Gaps = 44/164 (26%)
Query: 1031 YECHCQRGYQG-DGISHCN-RTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPP 1088
+ +C G++ G S C C CG G CS P TC A G
Sbjct: 64 FHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTC---------------ADGTL 108
Query: 1089 APRC--SRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGC-RPCQ 1145
AP C SR GCS C G C+ G C C+ G G G C R C
Sbjct: 109 APSCGVSRGSGCSV--SCMNGG-----TCR----GASC-LCQKGYTGTVCGQPICDRGCH 156
Query: 1146 CNGHG-DPRRGHC-----------DNLSGLCFCQDHTEGAHCQL 1177
G P R C D +G CF Q EG QL
Sbjct: 157 NGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQL 200
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 82.0 bits (201), Expect = 7e-15
Identities = 80/304 (26%), Positives = 113/304 (37%), Gaps = 66/304 (21%)
Query: 2132 PHGYECSCK---TGYTMDNMT--------GLCRPV-C-AQGCVNGSCVE-PDHCRCHFGF 2177
P+G +C C+ G T + C+P C QG VN C C C G
Sbjct: 787 PNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGV 846
Query: 2178 VGRNCST------------ECRCNRHSE-CAGVGARDHCLLCRNHTKGSHCEQCLPLFVG 2224
R C C+CN H++ C V CL C+++T G +CE+CL + G
Sbjct: 847 YARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGE--CLNCQDYTMGHNCERCLAGYYG 904
Query: 2225 SAV--GGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEA 2282
+ G CRPC +S +R Q DP + +
Sbjct: 905 DPIIGSGDHCRPCPCPDGPDSGRQFARSCYQ-----------DPVTL-----------QL 942
Query: 2283 VCVNCQNNSYGEKCESCLQGYF----LLDGKCTKCQCNGHADT-----CNEQDGTGCPCQ 2333
CV C G +C+ C GYF + G C CQC+ + DT C+++ G C
Sbjct: 943 ACV-CDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCL 1001
Query: 2334 NNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGS---PLGGQQCYRLISVEQECCLDPTS 2390
+TE CQ D + C KC ++ G+ G C + Q CL
Sbjct: 1002 YHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVI 1061
Query: 2391 QTNC 2394
NC
Sbjct: 1062 GQNC 1065
Score = 80.1 bits (196), Expect = 3e-14
Identities = 115/443 (25%), Positives = 150/443 (33%), Gaps = 93/443 (20%)
Query: 1014 GLA-RCHPRATCLNT--PLSYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVC 1070
GLA C P+ + + P +C C+ G CNR G G P C C
Sbjct: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVG---RTCNRCAPGTFGFGPSGCKP---CEC 823
Query: 1071 DL-GWTSDLPPPTPAP-----GPPAPRCSR------------DCGCSFHSHCRKRGPGFC 1112
L G + P G A +C R C C+ H+ G C
Sbjct: 824 HLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGEC 883
Query: 1113 DECQDWTWGEHCERCRPGSFGNATGSRG--CRPCQCNGHGDPRRGHCDN-------LSGL 1163
CQD+T G +CERC G +G+ G CRPC C D R + L
Sbjct: 884 LNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLA 943
Query: 1164 CFCQDHTEGAHCQLCSPGYYGDP-RAGGSCFR-ECGGRALLTNVSSVALGSRRVGGLLPP 1221
C C G+ C C+ GY+G+P GGSC +C T+ + + G L
Sbjct: 944 CVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEAC---DKETGRCLK- 999
Query: 1222 GGGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTPCTLSYVLAFDGFP 1281
C++ E Q C G L C +Y+
Sbjct: 1000 -------------CLYHTEG-EHCQFCRFGYYGDAL-----QQDCRKCVCNYLGTVQEHC 1040
Query: 1282 RFLDTGVVQSDRSLIAAFC-----GQRRDR--PLTVQALSGLLVLHWEANGSSSWG--FN 1332
D Q D++ C GQ DR P T Q SG N + S+G N
Sbjct: 1041 NGSD---CQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCN 1097
Query: 1333 ASVGSARCGSG-GPGSCPVPQECVPQDGAAGAGLCRC-PQGWAGPHCRMALCPENCNAHT 1390
G +C G G +C QE D C C P+G P
Sbjct: 1098 EFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQ-------------- 1143
Query: 1391 GAGTCNQSLGVCICAEGFGGPDC 1413
C+QS G C+C EG GP C
Sbjct: 1144 ----CDQSTGQCVCVEGVEGPRC 1162
Score = 67.8 bits (164), Expect = 1e-10
Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 30/165 (18%)
Query: 1056 GHGVCS-GPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHS-HCR-------- 1105
GH +C C + + DLP PA G + C + C C+ HS C
Sbjct: 296 GHCMCRHNTKGLNCELCMDFYHDLPW-RPAEGRNSNACKK-CNCNEHSISCHFDMAVYLA 353
Query: 1106 --KRGPGFCDECQDWTWGEHCERCRPGSF----GNATGSRGCRPCQCNGHGDPRRGHCDN 1159
G CD+CQ T G +CE+C+P + + C C C+ G G CD+
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 1160 --------LSGLCFCQDHTEGAHCQLCSPGYYG----DPRAGGSC 1192
++G C C+ + EG HC +C G+Y DP SC
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSC 458
Score = 60.5 bits (145), Expect = 2e-08
Identities = 44/153 (28%), Positives = 59/153 (38%), Gaps = 30/153 (19%)
Query: 1032 ECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCV-CDLGWTSDLPPPTPAPGPPAP 1090
+C C+ +G+ HC+ C E G S F C C +P P
Sbjct: 425 QCRCKLNVEGE---HCD-VCKE--GFYDLSSEDPFGCKSCACNPLGTIPGGNP------- 471
Query: 1091 RCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHG 1150
C + G HC C+ G+HC++C P +G + GCRPC C+ G
Sbjct: 472 -CDSETG-----HCY---------CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCD-LG 515
Query: 1151 DPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
C SG C C+ H G C PGYY
Sbjct: 516 GALNNSCFAESGQCSCRPHMIGRQCNEVEPGYY 548
Score = 59.7 bits (143), Expect = 4e-08
Identities = 93/383 (24%), Positives = 115/383 (30%), Gaps = 100/383 (26%)
Query: 876 PEECPPLCSQRLTCEDCLANSSQCAWCQS-THTCFLFAAYLARY------PHGG------ 922
P C P CE C S A+C T C F AR H G
Sbjct: 815 PSGCKP-------CE-CHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQP 866
Query: 923 --CRGW-DDSVHSEPRCRSCDGFL---TCHECLQSH----------ECGWCGNEDNPTLG 966
C G DD C +C + C CL + C C D P G
Sbjct: 867 CQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSG 926
Query: 967 R-----CLQGDFSGPLG--------GGNCSLWVGEGLGLPVALPARWAYARC------PD 1007
R C Q + L G C G P + +C D
Sbjct: 927 RQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTD 986
Query: 1008 VDECRLGLARCHPRATCLNTPLSYECH-CQRGYQGDGISHCNRTCL--------EDCGHG 1058
+ C RC CL C C+ GY GD + R C+ E C
Sbjct: 987 PEACDKETGRC---LKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGS 1043
Query: 1059 VCS-GPPDFTCVC---DLGWTSDLPPPTP---APGPPAPRCSRDCGCSFHSHCRKRG--- 1108
C C+C +G D P A G C+ + SF C +
Sbjct: 1044 DCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQC 1103
Query: 1109 ---PGF----CDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLS 1161
PGF C ECQ+ WG+ CR C C+ G CD +
Sbjct: 1104 QCMPGFGGRTCSECQELFWGDPDVECRA--------------CDCDPRGI-ETPQCDQST 1148
Query: 1162 GLCFCQDHTEGAHCQLCSPGYYG 1184
G C C + EG C C+ GY G
Sbjct: 1149 GQCVCVEGVEGPRCDKCTRGYSG 1171
Score = 57.8 bits (138), Expect = 1e-07
Identities = 61/241 (25%), Positives = 89/241 (36%), Gaps = 50/241 (20%)
Query: 2113 DECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEP---- 2168
D C GH Q C H +C TG ++ C + C+ G +P
Sbjct: 852 DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNC-ERCLAGYYGDPIIGS 910
Query: 2169 -DHCR---CHFG-FVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFV 2223
DHCR C G GR + C + V + C +C GS C+ C +
Sbjct: 911 GDHCRPCPCPDGPDSGRQFARSCYQD------PVTLQLAC-VCDPGYIGSRCDDCASGYF 963
Query: 2224 GS-AVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEA 2282
G+ + GG+C+PC C N + DPE + ++
Sbjct: 964 GNPSEVGGSCQPCQ--CHNNID------------------TTDPEACD--------KETG 995
Query: 2283 VCVNCQNNSYGEKCESCLQGYF--LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGT 2340
C+ C ++ GE C+ C GY+ L C KC CN +G+ C C + TG
Sbjct: 996 RCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQC--DKATGQ 1053
Query: 2341 C 2341
C
Sbjct: 1054 C 1054
Score = 55.8 bits (133), Expect = 6e-07
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 17/94 (18%)
Query: 1121 GEHCERCRPGSFG-NATGSRGCRPCQCNGHGD-PRRGHCDNLSGLCFCQDHTEGAHCQLC 1178
GEHC+ C+ G + ++ GC+ C CN G P CD+ +G C+C+ G HC C
Sbjct: 434 GEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQC 493
Query: 1179 SPGYYG-----------DPRAGG----SCFRECG 1197
P ++G D GG SCF E G
Sbjct: 494 LPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESG 527
Score = 54.7 bits (130), Expect = 1e-06
Identities = 59/206 (28%), Positives = 75/206 (36%), Gaps = 41/206 (19%)
Query: 2128 CHDQPHGYECS-CKTGYTMDNMTGLCRP-VC-----AQGCVNGSCVEPD----HCRCHFG 2176
C G C C+ GY D + CR VC Q NGS + D C C
Sbjct: 1000 CLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPN 1059
Query: 2177 FVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCE------QCLPLFVGSAVGGG 2230
+G+NC C N +G G D C H+ G C QC+P F GG
Sbjct: 1060 VIGQNCD-RCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGF-----GGR 1112
Query: 2231 TCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNN 2290
TC C G+ + E + DP IE T + CV C
Sbjct: 1113 TCSECQELFWGDPDV------------ECRACDCDPRGIE---TPQCDQSTGQCV-CVEG 1156
Query: 2291 SYGEKCESCLQGYFLLDGKCTKC-QC 2315
G +C+ C +GY + CT C QC
Sbjct: 1157 VEGPRCDKCTRGYSGVFPDCTPCHQC 1182
Score = 53.5 bits (127), Expect = 3e-06
Identities = 54/216 (25%), Positives = 78/216 (36%), Gaps = 55/216 (25%)
Query: 2186 CRCNRH-SECAGVGA---------RDHCLLCRNHTKGSHCEQC------LPLFVGSAVGG 2229
C C H SECA V HC+ CR++TKG +CE C LP
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 2230 GTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQN 2289
C+ C+ C +S C + ++ G V+ G VC +CQ+
Sbjct: 330 NACKKCN--CNEHSISCHFDMAVYLATGN--------------VSGG------VCDDCQH 367
Query: 2290 NSYGEKCESCLQGYFLLDGK-------CTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQ 2342
N+ G CE C Y+ + C +C C D Q+ C + TG
Sbjct: 368 NTMGRNCEQCKPFYYQHPERDIRDPNFCERCTC----DPAGSQNEGICDSYTDFSTGLIA 423
Query: 2343 GSSPSDRRDCYKYQCAKCRESFHG----SPLGGQQC 2374
G + + C C+E F+ P G + C
Sbjct: 424 GQCRC-KLNVEGEHCDVCKEGFYDLSSEDPFGCKSC 458
Score = 46.6 bits (109), Expect = 3e-04
Identities = 57/266 (21%), Positives = 83/266 (31%), Gaps = 107/266 (40%)
Query: 2127 NCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCST-- 2184
NC H EC+ G+ + +G V+G HC C G NC
Sbjct: 270 NCFCYGHASECAPVDGFNEE----------VEGMVHG------HCMCRHNTKGLNCELCM 313
Query: 2185 --------------------ECRCNRHS-EC---------AGVGARDHCLLCRNHTKGSH 2214
+C CN HS C G + C C+++T G +
Sbjct: 314 DFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN 373
Query: 2215 CEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVT 2274
CEQC P + P++ DP E
Sbjct: 374 CEQCKPFYY---------------------------------QHPERDIRDPNFCERCTC 400
Query: 2275 E-GPSEDEAVC--------------VNCQNNSYGEKCESCLQGYFLLDGK----CTKCQC 2315
+ S++E +C C+ N GE C+ C +G++ L + C C C
Sbjct: 401 DPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCAC 460
Query: 2316 NGHADTCNEQDGTGCPCQNNTETGTC 2341
N G PC ++ETG C
Sbjct: 461 NPLGTIPG-----GNPC--DSETGHC 479
Score = 44.3 bits (103), Expect = 0.002
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 31/133 (23%)
Query: 2121 DCNETQNCHDQPHGYE----CSCKTGYTMDNMTGLCR----------PVCAQGCVNGSCV 2166
D N + C P G + C T ++ + G CR VC +G + S
Sbjct: 391 DPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSE 450
Query: 2167 EPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARD----HCLLCRNHTKGSHCEQCLPLF 2222
+P C+ C CN G D HC C+ G HC+QCLP
Sbjct: 451 DPFGCK------------SCACNPLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEH 497
Query: 2223 VGSAVGGGTCRPC 2235
G + CRPC
Sbjct: 498 WGLSNDLDGCRPC 510
Score = 38.9 bits (89), Expect = 0.071
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 9/67 (13%)
Query: 1353 ECVPQDGAAGAGLCRC-PQGW---AGPHCRMALCPENCNA-HTGAGTCNQSLGVCICAEG 1407
+C+ G RC P W +G C P NCNA H+ +CN+ G C C G
Sbjct: 1053 QCLCLPNVIGQNCDRCAPNTWQLASGTGCD----PCNCNAAHSFGPSCNEFTGQCQCMPG 1108
Query: 1408 FGGPDCA 1414
FGG C+
Sbjct: 1109 FGGRTCS 1115
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 81.3 bits (199), Expect = 1e-14
Identities = 51/140 (36%), Positives = 68/140 (48%), Gaps = 14/140 (10%)
Query: 1059 VCSGPPDF---TCV-CDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFCDE 1114
+C+ PP + +C C G+ D G RC C C+ HS+ + G G C
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRD------HKGLYTGRCV-PCNCNGHSNQCQDGSGICVN 1705
Query: 1115 CQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSGL-CFCQDHTEGA 1173
CQ T GEHCERC+ G +GNA CR C C G N + C C+ G
Sbjct: 1706 CQHNTAGEHCERCQEGYYGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 1174 HCQLCSPGYYGDP-RAGGSC 1192
C+ C+PGY+G+P + GGSC
Sbjct: 1765 QCERCAPGYFGNPQKFGGSC 1784
Score = 65.5 bits (158), Expect = 7e-10
Identities = 47/174 (27%), Positives = 74/174 (42%), Gaps = 32/174 (18%)
Query: 2185 ECRCNRHSECAGVGARDHCLLC--RNHTKGSHCEQCLPLF------VGSAVGGGTCRPCH 2236
+C CN H+E + + C ++HT G C++C + + C C+
Sbjct: 298 QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACN 357
Query: 2237 AFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKC 2296
C G++ C ++ E ++ SL+ T+G VC+NCQ+N+ G C
Sbjct: 358 --CHGHASNCYYDPDV-----ERQQASLN--------TQGIYAGGGVCINCQHNTAGVNC 402
Query: 2297 ESCLQGYFLLDG-------KCTKCQCN-GHADTCNEQDGTGCPCQNNTETGTCQ 2342
E C +GY+ G C C C+ HAD C EQ C C+ N C+
Sbjct: 403 EQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGC-EQGSGRCHCKPNFHGDNCE 455
Score = 63.2 bits (152), Expect = 4e-09
Identities = 60/221 (27%), Positives = 82/221 (37%), Gaps = 71/221 (32%)
Query: 2137 CSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAG 2196
C+C Y D+ QGC P + R H G C C CN HS
Sbjct: 1654 CACPPAYAGDS---------CQGC------SPGYYRDHKGLYTGRC-VPCNCNGHSNQCQ 1697
Query: 2197 VGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPC-----HAFCRGNSHICISRKE 2251
G+ C+ C+++T G HCE+C + G+AV G+CR C ++F G C+
Sbjct: 1698 DGS-GICVNCQHNTAGEHCERCQEGYYGNAV-HGSCRACPCPHTNSFATG----CV---- 1747
Query: 2252 LQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF----LLD 2307
++ G+ V +C+ G +CE C GYF
Sbjct: 1748 --VNGGD------------------------VRCSCKAGYTGTQCERCAPGYFGNPQKFG 1781
Query: 2308 GKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSD 2348
G C C CN N Q G+ P TG C P D
Sbjct: 1782 GSCQPCSCNS-----NGQLGSCHPL-----TGDCINQEPKD 1812
Score = 60.5 bits (145), Expect = 2e-08
Identities = 79/326 (24%), Positives = 110/326 (33%), Gaps = 56/326 (17%)
Query: 1108 GPGFCDECQDWTWGEHCERCRPGSFGN----ATGSRGCRPCQCNGHGDPRRGH-CDNLSG 1162
G G C CQ T G +CE+C G + GC PC C DP C+ SG
Sbjct: 386 GGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSC----DPEHADGCEQGSG 441
Query: 1163 LCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTNVSSVALGSRRVGGLLPPG 1222
C C+ + G +C+ C+ GYY P C R + V+ S P
Sbjct: 442 RCHCKPNFHGDNCEKCAIGYYNFP----FCLR--------IPIFPVSTPSSED----PVA 485
Query: 1223 GGAARAGPGLSYCVWVVSATEELQPCAPGTLCPPLTLTFSPDSSTP-CTLSYVLAFDGFP 1281
G L + + C PG P S S P C + A +
Sbjct: 486 GDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQ 545
Query: 1282 RFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVL-HWEANGSS---SWGFNASVGS 1337
+ V GQR DR LSG H + + S+ + N+++G
Sbjct: 546 --MPCSSVTGQCECRPGVTGQRCDR-----CLSGAYDFPHCQGSSSACDPAGTINSNLGY 598
Query: 1338 ARC--GSGGP--GSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAG 1393
+C GP C + + ++ +G C+C +G G
Sbjct: 599 CQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKC---------------HKAGTVSGTG 643
Query: 1394 TCNQSLGVCICAEGFGGPDCATKLDG 1419
C Q G C C GG C T DG
Sbjct: 644 ECRQGDGDCHCKSHVGGDSCDTCEDG 669
Score = 59.3 bits (142), Expect = 5e-08
Identities = 62/252 (24%), Positives = 88/252 (34%), Gaps = 49/252 (19%)
Query: 934 PRCRSC-DGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGL 992
PRC +C GF + C Q+ C G+ P Q + + G C +
Sbjct: 518 PRCDTCRSGFYSFPIC-QACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDF 576
Query: 993 PVALPARWAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQGDGISHCNRTCL 1052
P C+ + C P T +N+ L Y C C+ +G S C
Sbjct: 577 P----------------HCQGSSSACDPAGT-INSNLGY-CQCKLHVEGPTCSRCKL--- 615
Query: 1053 EDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHCRKRGPGFC 1112
L W D P+ G +C + S CR+ G G C
Sbjct: 616 -------------------LYWNLDKENPS---GCSECKCHKAGTVSGTGECRQ-GDGDC 652
Query: 1113 DECQDWTWGEHCERCRPGSFG-NATGSRGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTE 1171
C+ G+ C+ C G F + GC+ CQC+ G C SG+C C++H
Sbjct: 653 -HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCD-IGGALSSMCSGPSGVCQCREHVV 710
Query: 1172 GAHCQLCSPGYY 1183
G CQ YY
Sbjct: 711 GKVCQRPENNYY 722
Score = 56.6 bits (135), Expect = 3e-07
Identities = 44/165 (26%), Positives = 60/165 (36%), Gaps = 57/165 (34%)
Query: 2212 GSHCEQCLPLFVGSAVG--GGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEI 2269
G C+ C P + G G C PC+ C G+S+ C
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCN--CNGHSNQC----------------------- 1696
Query: 2270 ENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF--LLDGKCTKCQC---NGHADTCNE 2324
+ +CVNCQ+N+ GE CE C +GY+ + G C C C N A C
Sbjct: 1697 --------QDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVV 1748
Query: 2325 QDG-TGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKCRESFHGSP 2368
G C C+ TGT QC +C + G+P
Sbjct: 1749 NGGDVRCSCKAG-YTGT---------------QCERCAPGYFGNP 1777
Score = 55.5 bits (132), Expect = 7e-07
Identities = 90/354 (25%), Positives = 115/354 (32%), Gaps = 76/354 (21%)
Query: 1096 CGCSFHSH-CRKRGPG--FCDECQDWTWGEHCERC---------RPGSFGNATGSRGCRP 1143
C C+ H+ C P F ECQ T GE C+RC RP ++ S C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQ---SHECEA 355
Query: 1144 CQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLT 1203
C C+GH + C+ E L + G Y AGG C
Sbjct: 356 CNCHGH-----------ASNCYYDPDVERQQASLNTQGIY----AGGGVCINCQHNTAGV 400
Query: 1204 NVSSVALGSRRVGGLLPPGGGAARAGPGLSYCVWVVSATEELQPCAPGT---LCPPLTLT 1260
N A G R P G A G C+ E C G+ C P
Sbjct: 401 NCEQCAKGYYR------PYGVPVDAPDG---CIPCSCDPEHADGCEQGSGRCHCKP---N 448
Query: 1261 FSPDSSTPCTLSYVLAFDGFPRFLDTGVVQ-SDRSLIAAFCGQRRDRPLTVQALSGLLVL 1319
F D+ C + Y FP L + S S G + L G+L
Sbjct: 449 FHGDNCEKCAIGYY----NFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCN---LEGVLPE 501
Query: 1320 HWEANGSSSWGFNASVGSARCGSGGPG--SCPVPQEC---------VPQDGAAGAGLCRC 1368
+A+G V RC + G S P+ Q C +P G C C
Sbjct: 502 ICDAHGRCL--CRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQ--CEC 557
Query: 1369 PQGWAGPHCRMAL--------CPENCNAHTGAGTCNQSLGVCICAEGFGGPDCA 1414
G G C L C + +A AGT N +LG C C GP C+
Sbjct: 558 RPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCS 611
Score = 55.5 bits (132), Expect = 7e-07
Identities = 41/167 (24%), Positives = 59/167 (35%), Gaps = 29/167 (17%)
Query: 1030 SYECHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPA 1089
S CHC+ + GD +C + + C P F P TP+ P
Sbjct: 440 SGRCHCKPNFHGD---NCEKCAIGYYNFPFCLRIPIF------------PVSTPSSEDPV 484
Query: 1090 PRCSRDCGCSFHSHCRKRGPGFCDE-----CQDWTWGEHCERCRPGSFGNATGSRGCRPC 1144
+ C C+ P CD C+ G C+ CR G + C+ C
Sbjct: 485 AGDIKGCDCNLEGVL----PEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI----CQAC 536
Query: 1145 QCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPRAGGS 1191
C+ G + C +++G C C+ G C C G Y P GS
Sbjct: 537 WCSALGSYQMP-CSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGS 582
Score = 55.1 bits (131), Expect = 1e-06
Identities = 32/90 (35%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 1094 RDCGC----SFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRG-CRPCQCNG 1148
R C C SF + C G C+ G CERC PG FGN G C+PC CN
Sbjct: 1732 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNS 1791
Query: 1149 HGDPRRGHCDNLSGLCFCQDHTEGAHCQLC 1178
+G + G C L+G C Q+ + + + C
Sbjct: 1792 NG--QLGSCHPLTGDCINQEPKDSSPAEEC 1819
Score = 54.7 bits (130), Expect = 1e-06
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 23/108 (21%)
Query: 1090 PRCSRDCGCSFHSHCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGH 1149
P C RD G CR C+ G C+RC G + C PC CN
Sbjct: 1369 PECDRDSG-----QCR---------CKPRITGRQCDRCASGFYRFPE----CVPCNCNRD 1410
Query: 1150 GDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPG-YYGDP---RAGGSCF 1193
G G CD +G C C+++ EG C +C G ++ DP + SCF
Sbjct: 1411 GT-EPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
Score = 53.5 bits (127), Expect = 3e-06
Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 32/108 (29%)
Query: 2293 GEKCESCLQGYF-----LLDGKCTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPS 2347
G+ C+ C GY+ L G+C C CNGH++ C + G CQ+NT C+
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCE----- 1716
Query: 2348 DRRDCYKYQCAKCRESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCF 2395
+C+E ++G+ + G C P TN F
Sbjct: 1717 -----------RCQEGYYGNAVHG-----------SCRACPCPHTNSF 1742
Score = 47.8 bits (112), Expect = 2e-04
Identities = 42/172 (24%), Positives = 61/172 (35%), Gaps = 30/172 (17%)
Query: 1033 CHCQRGYQGDGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPA------PG 1086
C C+ G +G C + C G S P C C + +P + PG
Sbjct: 509 CLCRPGVEGP---RC-----DTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPG 560
Query: 1087 PPAPRCSRDCGCSFH-SHCRKRGP------------GFCDECQDWTWGEHCERCRPGSFG 1133
RC R ++ HC+ G+C +C+ G C RC+ +
Sbjct: 561 VTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC-QCKLHVEGPTCSRCKLLYWN 619
Query: 1134 -NATGSRGCRPCQCNGHGDPR-RGHCDNLSGLCFCQDHTEGAHCQLCSPGYY 1183
+ GC C+C+ G G C G C C+ H G C C GY+
Sbjct: 620 LDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Score = 47.4 bits (111), Expect = 2e-04
Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 19/105 (18%)
Query: 1090 PRCSRDCGCSFHSHCRKRGPGFCDE------CQDWTWGEHCERCRPGSFGNATGSRGCRP 1143
PRC + C C G C+E C T CE C SF + GC
Sbjct: 1307 PRC-KPCSC---------GRRLCEEMTGQCRCPPRTVRPQCEVCETHSF-SFHPMAGCEG 1355
Query: 1144 CQCNGHG--DPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDP 1186
C C+ G + CD SG C C+ G C C+ G+Y P
Sbjct: 1356 CNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP 1400
Score = 45.4 bits (106), Expect = 8e-04
Identities = 28/88 (31%), Positives = 36/88 (40%), Gaps = 13/88 (14%)
Query: 1103 HCRKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQCNGHGDPRRGHCDNLSG 1162
HC G G C CQ G C RC G +G C+PC C R C+ ++G
Sbjct: 1277 HCSPEG-GQCP-CQPNVIGRQCTRCATGHYGFPR----CKPCSCG------RRLCEEMTG 1324
Query: 1163 LCFCQDHTEGAHCQLCSPGYYG-DPRAG 1189
C C T C++C + P AG
Sbjct: 1325 QCRCPPRTVRPQCEVCETHSFSFHPMAG 1352
Score = 44.7 bits (104), Expect = 0.001
Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 72/298 (24%)
Query: 2108 SCPPE--DECANGHHDCNETQNCHDQPHGYECS-CKTGY------------------TMD 2146
SC PE D C G C+ C HG C C GY + D
Sbjct: 427 SCDPEHADGCEQGSGRCH----CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSED 482
Query: 2147 NMTGLCRPVCA--QGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSE-------CAGV 2197
+ G + +G + C C C G G C T CR +S C+ +
Sbjct: 483 PVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDT-CRSGFYSFPICQACWCSAL 541
Query: 2198 GARD--------HCLLCRNHTKGSHCEQCL------PLFVGSAVG---GGTCRPCHAFCR 2240
G+ C CR G C++CL P GS+ GT +C+
Sbjct: 542 GSYQMPCSSVTGQCE-CRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQ 600
Query: 2241 GNSHI----CISRKEL--QMSKGEPKKYSLDPEEIENWVTEGPSE---DEAVCVNCQNNS 2291
H+ C K L + K P S + + + G E + C +C+++
Sbjct: 601 CKLHVEGPTCSRCKLLYWNLDKENPSGCS-ECKCHKAGTVSGTGECRQGDGDC-HCKSHV 658
Query: 2292 YGEKCESCLQGYFLLDGK----CTKCQCN---GHADTCNEQDGTGCPCQNNTETGTCQ 2342
G+ C++C GYF L+ C CQC+ + C+ G C C+ + CQ
Sbjct: 659 GGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGV-CQCREHVVGKVCQ 715
Score = 43.1 bits (100), Expect = 0.004
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 1139 RGCRPCQCNGHGDPRRGHCDNLSGLCFCQDHTEGAHCQLCSPGYYGDPR 1187
+G PC+C+ G HC G C CQ + G C C+ G+YG PR
Sbjct: 1261 KGALPCECHPTG-ATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR 1308
Score = 42.7 bits (99), Expect = 0.005
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 13/65 (20%)
Query: 152 CQPPGVCACEPGWGGPDC--------GLQECSA-YCGSHGT----CASPLGPCRCEPGFL 198
C G C C PG GP C C A +C + G+ C+S G C C PG
Sbjct: 503 CDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVT 562
Query: 199 GRACD 203
G+ CD
Sbjct: 563 GQRCD 567
Score = 42.4 bits (98), Expect = 0.006
Identities = 41/151 (27%), Positives = 52/151 (34%), Gaps = 24/151 (15%)
Query: 1279 GFPRFLDTGVVQSDRSLIAAFCGQRRDRPLTVQALSGLLVLHWEANGSSSWGFNASVGSA 1338
GFPR R L GQ R P TV+ + H S+ F+ G
Sbjct: 1305 GFPRCKPCSC---GRRLCEEMTGQCRCPPRTVRPQCEVCETH-------SFSFHPMAGCE 1354
Query: 1339 RCGSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHC--------RMALC-PENCNAH 1389
C G+ +D +G CRC G C R C P NCN
Sbjct: 1355 GCNCSRRGTIEAAMPECDRD----SGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRD 1410
Query: 1390 -TGAGTCNQSLGVCICAEGFGGPDCATKLDG 1419
T G C+ G C+C E G +C +G
Sbjct: 1411 GTEPGVCDPGTGACLCKENVEGTECNVCREG 1441
Score = 41.6 bits (96), Expect = 0.011
Identities = 72/301 (23%), Positives = 97/301 (32%), Gaps = 83/301 (27%)
Query: 2115 CANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCH 2174
C HH C ET + C TGY RP + E + C CH
Sbjct: 319 CECQHHTCGETCD----------RCCTGYNQRRW----RPAAWE-----QSHECEACNCH 359
Query: 2175 FGFVGRNC-------STECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCL-----PLF 2222
NC + N AG G C+ C+++T G +CEQC P
Sbjct: 360 GH--ASNCYYDPDVERQQASLNTQGIYAGGGV---CINCQHNTAGVNCEQCAKGYYRPYG 414
Query: 2223 VGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEA 2282
V G C PC S DPE +G +
Sbjct: 415 VPVDAPDG-CIPC---------------------------SCDPEH-----ADGCEQGSG 441
Query: 2283 VCVNCQNNSYGEKCESCLQGYFLLDGKCTKCQCNGHADTCNEQ----DGTGCPCQNNTET 2338
C +C+ N +G+ CE C GY+ C + + +E D GC C N E
Sbjct: 442 RC-HCKPNFHGDNCEKCAIGYYNFP-FCLRIPIFPVSTPSSEDPVAGDIKGCDC--NLEG 497
Query: 2339 GTCQGSSPSDRRDCYK----YQCAKCRESFHGSPLGGQQCY-RLISVEQECCLDPTSQTN 2393
+ R C +C CR F+ P+ Q C+ + Q C T Q
Sbjct: 498 VLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPI-CQACWCSALGSYQMPCSSVTGQCE 556
Query: 2394 C 2394
C
Sbjct: 557 C 557
Score = 39.3 bits (90), Expect = 0.055
Identities = 56/252 (22%), Positives = 78/252 (30%), Gaps = 73/252 (28%)
Query: 2129 HDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTE--- 2185
H P G +C C+ N+ G CA G +P C C GR E
Sbjct: 1277 HCSPEGGQCPCQP-----NVIGRQCTRCATGHYGFPRCKP--CSC-----GRRLCEEMTG 1324
Query: 2186 -CRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSH 2244
CRC + R C +C H+ H P+ C C+ RG
Sbjct: 1325 QCRCPPRT------VRPQCEVCETHSFSFH-----PM--------AGCEGCNCSRRGTIE 1365
Query: 2245 ICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSEDEAVCVNCQNNSYGEKCESCLQGYF 2304
+ + D C C+ G +C+ C G++
Sbjct: 1366 AAMPECD---------------------------RDSGQC-RCKPRITGRQCDRCASGFY 1397
Query: 2305 LLDGKCTKCQCNGHADTCNEQD-GTG-CPCQNNTETGTC----QGS---SPSDRRDCYKY 2355
+C C CN D GTG C C+ N E C +GS P++ + C
Sbjct: 1398 RFP-ECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSC 1456
Query: 2356 QCAKCRESFHGS 2367
C H S
Sbjct: 1457 FCFGVNNQCHSS 1468
Score = 33.9 bits (76), Expect = 2.3
Identities = 25/83 (30%), Positives = 31/83 (37%), Gaps = 17/83 (20%)
Query: 137 FRFSLCPG-GCQSHGQCQPP-----GVCACEPGWGGPDCG-----------LQECSAYCG 179
+ F +C C + G Q P G C C PG G C Q S+ C
Sbjct: 528 YSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACD 587
Query: 180 SHGTCASPLGPCRCEPGFLGRAC 202
GT S LG C+C+ G C
Sbjct: 588 PAGTINSNLGYCQCKLHVEGPTC 610
Score = 33.9 bits (76), Expect = 2.3
Identities = 20/67 (29%), Positives = 24/67 (35%), Gaps = 19/67 (28%)
Query: 156 GVCACEPGWGGPDCGLQECSAY------------CGSHGT-------CASPLGPCRCEPG 196
G C C P P C + E ++ C GT C G CRC+P
Sbjct: 1324 GQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPR 1383
Query: 197 FLGRACD 203
GR CD
Sbjct: 1384 ITGRQCD 1390
Score = 32.3 bits (72), Expect = 6.7
Identities = 21/74 (28%), Positives = 25/74 (33%), Gaps = 9/74 (12%)
Query: 1341 GSGGPGSCPVPQECVPQDGAAGAGLCRCPQGWAG-PHCRMALCPENCNAHTGAGTCNQSL 1399
G+ GP P +C Q G RC G G P C+ C G C +
Sbjct: 1272 GATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSC--------GRRLCEEMT 1323
Query: 1400 GVCICAEGFGGPDC 1413
G C C P C
Sbjct: 1324 GQCRCPPRTVRPQC 1337
Score = 32.0 bits (71), Expect = 8.7
Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 19/78 (24%)
Query: 144 GGCQSHGQC-QPPGVCACEPGWGGPDC----------------GLQECSAYCGS--HGTC 184
G G+C Q G C C+ GG C G Q C G C
Sbjct: 637 GTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMC 696
Query: 185 ASPLGPCRCEPGFLGRAC 202
+ P G C+C +G+ C
Sbjct: 697 SGPSGVCQCREHVVGKVC 714
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.475
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,617,738
Number of Sequences: 37866
Number of extensions: 9273504
Number of successful extensions: 74853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 442
Number of HSP's successfully gapped in prelim test: 606
Number of HSP's that attempted gapping in prelim test: 46639
Number of HSP's gapped (non-prelim): 22368
length of query: 2778
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2658
effective length of database: 13,703,598
effective search space: 36424163484
effective search space used: 36424163484
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.