Guide to the Human Genome
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Name: CUBN Sequence: fasta or formatted (3623aa) NCBI GI: 126091152
Description:

cubilin

Referenced in:

Epidermal Growth Factor
Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.1        147           2
 C cysteine            4.3        154           1
 D aspartate           5.4        194           2
 E glutamate           4.4        160           2
 F phenylalanine       5.5        201           2
 G glycine             9.0        325           3
 H histidine           2.9        104           2
 I isoleucine          5.5        198           3
 K lysine              2.3         84           2
 L leucine             7.1        259           3
 M methionine          1.2         44           2
 N asparagine          6.3        228           2
 P proline             6.2        224           3
 Q glutamine           4.0        145           2
 R arginine            3.8        137           2
 S serine             10.6        385           3
 T threonine           6.7        244           2
 V valine              5.2        188           2
 W tryptophan          1.5         53           2
 Y tyrosine            4.1        149           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cubilin 
LOC643321             0.057   PREDICTED: similar to hCG1644292 
LOC643321             0.057   PREDICTED: similar to hCG1644292 
TLL1                  0.039   tolloid-like 1 
TLL2                  0.038   tolloid-like 2 
BMP1                  0.037   bone morphogenetic protein 1 isoform 3 precursor [Hom...
JAG1                  0.025   jagged 1 precursor 
NOTCH1                0.024   notch1 preproprotein 
NOTCH3                0.024   Notch homolog 3 
CDCP2                 0.024   CUB domain containing protein 2 
NOTCH2                0.024   notch 2 preproprotein 
BMP1                  0.024   bone morphogenetic protein 1 isoform 2 precursor [Hom...
BMP1                  0.023   bone morphogenetic protein 1 isoform 1 precursor [Hom...
NOTCH4                0.023   notch4 preproprotein 
JAG2                  0.023   jagged 2 isoform a precursor 
JAG2                  0.023   jagged 2 isoform b precursor 
CRB2                  0.020   crumbs homolog 2 
LTBP4                 0.020   latent transforming growth factor beta binding prot...
LTBP4                 0.020   latent transforming growth factor beta binding prot...
LTBP4                 0.020   latent transforming growth factor beta binding prot...
EYS                   0.019   eyes shut homolog isoform 1 
CRB1                  0.019   crumbs homolog 1 precursor 
FBN1                  0.019   fibrillin 1 precursor 
DLL1                  0.017   delta-like 1 
PCOLCE2               0.016   procollagen C-endopeptidase enhancer 2 
FBN3                  0.016   fibrillin 3 precursor 
PCOLCE                0.016   procollagen C-endopeptidase enhancer 
FBN2                  0.016   fibrillin 2 precursor 
LTBP2                 0.016   latent transforming growth factor beta binding protei...
NRP2                  0.016   neuropilin 2 isoform 3 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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