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Search of human proteins with 145309306
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
(744 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 1625 0.0
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 1538 0.0
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 789 0.0
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 431 e-120
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 431 e-120
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 237 3e-62
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 234 2e-61
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 230 3e-60
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 222 1e-57
gi|21264602 laminin alpha 5 [Homo sapiens] 122 1e-27
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 120 6e-27
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 119 8e-27
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 118 2e-26
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 118 2e-26
gi|153946395 tenascin C precursor [Homo sapiens] 118 2e-26
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 115 2e-25
gi|148833508 notch1 preproprotein [Homo sapiens] 114 4e-25
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 112 1e-24
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 110 4e-24
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 110 5e-24
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 110 5e-24
gi|134244285 Notch homolog 3 [Homo sapiens] 108 2e-23
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 108 2e-23
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 106 7e-23
gi|219842266 usherin isoform B [Homo sapiens] 106 9e-23
gi|219842259 usherin isoform A [Homo sapiens] 106 9e-23
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 105 2e-22
gi|4557679 jagged 1 precursor [Homo sapiens] 103 6e-22
gi|55770876 notch4 preproprotein [Homo sapiens] 103 6e-22
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 102 1e-21
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 1625 bits (4208), Expect = 0.0
Identities = 744/744 (100%), Positives = 744/744 (100%)
Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP
Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC
Sbjct: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV
Sbjct: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
Query: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP
Sbjct: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
Query: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCACCCW 360
TFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCACCCW
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCACCCW 360
Query: 361 APRSDLKDRPARDGATVSRMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFN 420
APRSDLKDRPARDGATVSRMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFN
Sbjct: 361 APRSDLKDRPARDGATVSRMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFN 420
Query: 421 HSFIEPPSAGWATDDSFSSDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPP 480
HSFIEPPSAGWATDDSFSSDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPP
Sbjct: 421 HSFIEPPSAGWATDDSFSSDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPP 480
Query: 481 PEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSG 540
PEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSG
Sbjct: 481 PEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSG 540
Query: 541 PEGREAEESTGPEEAEAPESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSG 600
PEGREAEESTGPEEAEAPESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSG
Sbjct: 541 PEGREAEESTGPEEAEAPESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSG 600
Query: 601 PVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLA 660
PVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLA
Sbjct: 601 PVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLA 660
Query: 661 SGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQK 720
SGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQK
Sbjct: 661 SGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQK 720
Query: 721 QAEEERQEEPEYENVVPISRPPEP 744
QAEEERQEEPEYENVVPISRPPEP
Sbjct: 721 QAEEERQEEPEYENVVPISRPPEP 744
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 1538 bits (3982), Expect = 0.0
Identities = 727/830 (87%), Positives = 728/830 (87%), Gaps = 86/830 (10%)
Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP
Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC
Sbjct: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV
Sbjct: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
Query: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP
Sbjct: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ----- 295
PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
Query: 296 ----------------------------------------PCLPGTFGESCEQQCPHCRH 315
PC GTFGE C CP C
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQ 360
Query: 316 GEA-----------------------------------------CEPDTGHCQRCSGSRD 334
G C P +G CQ SGSRD
Sbjct: 361 GSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRD 420
Query: 335 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 394
TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST
Sbjct: 421 TALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGTLTSLGST 480
Query: 395 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV 454
LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV
Sbjct: 481 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFSSDPESGEADEVPAYCV 540
Query: 455 PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP 514
PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP
Sbjct: 541 PPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAEGTKFAP 600
Query: 515 QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH 574
QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH
Sbjct: 601 QSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPAAASPGDSATGH 660
Query: 575 RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA 634
RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA
Sbjct: 661 RRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGPVRSVFRHFGSFQKGQA 720
Query: 635 EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL 694
EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL
Sbjct: 721 EAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGL 780
Query: 695 GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 744
GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP
Sbjct: 781 GAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPISRPPEP 830
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 789 bits (2038), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP
Sbjct: 1 MGLGLLLPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGP 60
Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC
Sbjct: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC 120
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV
Sbjct: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
Query: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP
Sbjct: 181 CKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCP 240
Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
Query: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRC 329
TFGESCEQQCPHCRHGEACEPDTGHCQRC
Sbjct: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRC 329
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 431 bits (1108), Expect = e-120
Identities = 176/328 (53%), Positives = 218/328 (66%), Gaps = 7/328 (2%)
Query: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAELQ-CCAGWRQKDQECTIPICEGPDA 62
LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG
Sbjct: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85
Query: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122
C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A
Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
Query: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182
RWGARCE C C HG C P +G C CEPGWW + C C C+ A +RC+ TGAC+C
Sbjct: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYCS-ATSRCDPQTGACLCH 203
Query: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG
Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263
Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
+RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCS 330
GE C +CP CR G AC TG C RC+
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCN 351
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 431 bits (1108), Expect = e-120
Identities = 176/328 (53%), Positives = 218/328 (66%), Gaps = 7/328 (2%)
Query: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAEL-QCCAGWRQKDQECTIPICEGPDA 62
LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG
Sbjct: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85
Query: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122
C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A
Sbjct: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
Query: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182
RWGARCE C C HG C P +G C CEPGWW + C C C +A +RC+ TGAC+C
Sbjct: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYC-SATSRCDPQTGACLCH 203
Query: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG
Sbjct: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263
Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
+RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCS 330
GE C +CP CR G AC TG C RC+
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCN 351
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 237 bits (605), Expect = 3e-62
Identities = 123/347 (35%), Positives = 162/347 (46%), Gaps = 61/347 (17%)
Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
QCC G+ + + C +P C D C C+ P C+C+PG+ G +CSS C G +WGP C
Sbjct: 93 QCCPGFYESGEMC-VPHCA--DKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148
Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-------------CDPATG 146
C C C P TGAC C A G RCE C G +G CD TG
Sbjct: 149 TSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTG 208
Query: 147 VCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGW--------- 185
C C PG+ + C C +CEQ TG C C GW
Sbjct: 209 ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPC 268
Query: 186 ----WGRRCSFRCNCH-GSPCEQDSGRCACRPGWWGPECQQQ-------------CECVR 227
+G+ CS C CH G C+ +G+C C PG+ G CQ + C+CV
Sbjct: 269 PEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVN 328
Query: 228 -GRCSAASGECTCPPGFRGARCELP-CPAGSHGVQCAHSCG-RCKHNEPCSPDTGSCESC 284
G+C SG C C GF G RCE CP G +G++C C ++ C P +G C +C
Sbjct: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGEC-AC 387
Query: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSG 331
+PGW+G C + C PG +GE+C+Q C C++G C+ TG C G
Sbjct: 388 KPGWSGLYCNETCSPGFYGEACQQIC-SCQNGADCDSVTGKCTCAPG 433
Score = 224 bits (572), Expect = 2e-58
Identities = 121/366 (33%), Positives = 157/366 (42%), Gaps = 72/366 (19%)
Query: 36 SAELQCCAGWRQKDQECTIPICEGPDA--------CQKDEVC-VKPGLCRCKPGFFGAHC 86
+ E C +GW C P EG C C G C C PG+ G C
Sbjct: 250 TGECSCPSGWM--GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEF--------------- 131
CP +G C E+C C G+C +GAC C+A G RCE
Sbjct: 308 QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKR 367
Query: 132 -PCACGPHGRCDPATGVCHCEPGW-------------WSSTCRRPCQCNTAAARCEQATG 177
PC C P +G C C+PGW + C++ C C A C+ TG
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD-CDSVTG 426
Query: 178 ACVCKPGW-------------WGRRCSFRCNC-HGSPCEQDSGRCACRPGW--------- 214
C C PG+ +G CS RC C + + C G C C+ GW
Sbjct: 427 KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC 486
Query: 215 ----WGPECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK 269
WG C C+C+ G C+ G CTC PG+RG +CELPC G++G+ CA C C
Sbjct: 487 PSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD-CS 545
Query: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
H + C P TG C C PGW+G C C G +G +C C +C++G +C PD G C+
Sbjct: 546 HADGCHPTTGHCR-CLPGWSGVHCDSVCAEGRWGPNCSLPC-YCKNGASCSPDDGICECA 603
Query: 330 SGSRDT 335
G R T
Sbjct: 604 PGFRGT 609
Score = 205 bits (522), Expect = 1e-52
Identities = 124/362 (34%), Positives = 152/362 (41%), Gaps = 62/362 (17%)
Query: 34 SPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHC 86
S + + C G++ D P+ C C+ D VC G C CK G+ G C
Sbjct: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-----RC 141
S RCP WG C +C C G C G C C G +CE PC G +G RC
Sbjct: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542
Query: 142 D--------PATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
D P TG C C PGW + C+ VC G WG CS
Sbjct: 543 DCSHADGCHPTTGHCRCLPGW-------------SGVHCDS-----VCAEGRWGPNCSLP 584
Query: 194 CNC-HGSPCEQDSGRCACRPGWWGPECQQQC--------------ECVR--GRCSAASGE 236
C C +G+ C D G C C PG+ G CQ+ C +CV G C +G
Sbjct: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP 296
C C PGF GA C CP+G G CA C C +N C+P SC+ C PGW G+ C QP
Sbjct: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSCQ-CYPGWIGSDCSQP 702
Query: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCA 356
C P +G +C C +C +G C G C+ G T L P L F G C
Sbjct: 703 CPPAHWGPNCIHTC-NCHNGAFCSAYDGECKCTPGW--TGLYCTQRCP--LGFYGKDCAL 757
Query: 357 CC 358
C
Sbjct: 758 IC 759
Score = 202 bits (514), Expect = 9e-52
Identities = 103/310 (33%), Positives = 129/310 (41%), Gaps = 58/310 (18%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
G C CKPG+ G +C+ C ++G C++ C C C+ TG C C G C P
Sbjct: 383 GECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTP 442
Query: 133 CACGPHG-------------RCDPATGVCHCEPGW-------------WSSTCRRPCQCN 166
C G +G C P G C C+ GW W C CQC
Sbjct: 443 CPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCL 502
Query: 167 TAAARCEQATGACVCKPGWWGRRCSF-------------RCNC-HGSPCEQDSGRCACRP 212
A C G C C PGW G +C RC+C H C +G C C P
Sbjct: 503 NGGA-CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLP 561
Query: 213 GW-------------WGPECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAGSHG 258
GW WGP C C C G CS G C C PGFRG C+ C G +G
Sbjct: 562 GWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYG 621
Query: 259 VQCAHSCGRCKHNE-PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGE 317
+C+ +C +C H+ PC TG C+ C PG+ G C + C G FG++C C C +
Sbjct: 622 HRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALCNEVCPSGRFGKNCAGICT-CTNNG 679
Query: 318 ACEPDTGHCQ 327
C P CQ
Sbjct: 680 TCNPIDRSCQ 689
Score = 200 bits (508), Expect = 5e-51
Identities = 115/358 (32%), Positives = 139/358 (38%), Gaps = 65/358 (18%)
Query: 31 VASSPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVC-VKPGLCRCKPGFFG 83
V S C AGW D P C C C G C C PG+ G
Sbjct: 463 VCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRG 522
Query: 84 AHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQC-------------QADRWGARCE 130
C C +G +C E C C C P TG C+C RWG C
Sbjct: 523 EKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCS 582
Query: 131 FPCACGPHGRCDPATGVCHCEPGWWSSTCRRPC--------------QCNTAAARCEQAT 176
PC C C P G+C C PG+ +TC+R C QC ++ C T
Sbjct: 583 LPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHIT 642
Query: 177 GACVCKPGWWGRRCSFRC-------NCHG-------SPCEQDSGRCACRPGW-------- 214
G C C PG+ G C+ C NC G C C C PGW
Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
Query: 215 -----WGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRC 268
WGP C C C G CSA GEC C PG+ G C CP G +G CA C +C
Sbjct: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALIC-QC 761
Query: 269 KHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
++ C +G C +C G+ G C+Q C GT+G C Q C C + C+ TG C
Sbjct: 762 QNGADCDHISGQC-TCRTGFMGRHCEQKCPSGTYGYGCRQIC-DCLNNSTCDHITGTC 817
Score = 186 bits (471), Expect = 9e-47
Identities = 103/319 (32%), Positives = 127/319 (39%), Gaps = 68/319 (21%)
Query: 41 CCAGWRQKDQECTIPICEGP---------DACQKDEVCVKPGLCRCKPGFFGAHCSSRCP 91
C GWR ++C +P +G D D G CRC PG+ G HC S C
Sbjct: 516 CAPGWR--GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCA 573
Query: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR----------- 140
WGP+C C C C P G C+C G C+ C+ G +G
Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH 633
Query: 141 ----CDPATGVCHCEPGWWSSTCRRPCQCN------------TAAARCEQATGACVCKPG 184
C TG+C C PG+ + C C T C +C C PG
Sbjct: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPG 693
Query: 185 W-------------WGRRCSFRCNCH-GSPCEQDSGRCACRPGWWGPECQQQC------- 223
W WG C CNCH G+ C G C C PGW G C Q+C
Sbjct: 694 WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGK 753
Query: 224 ------ECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP 276
+C G C SG+CTC GF G CE CP+G++G C C C +N C
Sbjct: 754 DCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD-CLNNSTCDH 812
Query: 277 DTGSCESCEPGWNGTQCQQ 295
TG+C C PGW G +C Q
Sbjct: 813 ITGTC-YCSPGWKGARCDQ 830
Score = 119 bits (299), Expect = 8e-27
Identities = 64/209 (30%), Positives = 82/209 (39%), Gaps = 41/209 (19%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD--------- 123
GLC C PGF GA C+ CP +G +C C C +G C P +CQC
Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
Query: 124 ----RWGARCEFPCACGPHGRCDPATGVCHCEPGW-------------WSSTCRRPCQCN 166
WG C C C C G C C PGW + C CQC
Sbjct: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ 762
Query: 167 TAAARCEQATGACVCKPGWWGRRCSFRC-------------NC-HGSPCEQDSGRCACRP 212
A C+ +G C C+ G+ GR C +C +C + S C+ +G C C P
Sbjct: 763 NGAD-CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSP 821
Query: 213 GWWGPECQQQCECVRGRCSAASGECTCPP 241
GW G C Q + G ++ S T P
Sbjct: 822 GWKGARCDQAGVIIVGNLNSLSRTSTALP 850
Score = 90.1 bits (222), Expect = 7e-18
Identities = 47/141 (33%), Positives = 60/141 (42%), Gaps = 22/141 (15%)
Query: 40 QCCAGWRQKD--QECTIPICEGPDA-----CQKDEVC-VKPGLCRCKPGFFGAHCSSRCP 91
QC GW D Q C P GP+ C C G C+C PG+ G +C+ RCP
Sbjct: 689 QCYPGWIGSDCSQPCP-PAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCP 747
Query: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG------------ 139
++G DC C C C+ +G C C+ G CE C G +G
Sbjct: 748 LGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNN 807
Query: 140 -RCDPATGVCHCEPGWWSSTC 159
CD TG C+C PGW + C
Sbjct: 808 STCDHITGTCYCSPGWKGARC 828
Score = 67.4 bits (163), Expect = 5e-11
Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
+C G+ KD C + IC+ + D + G C C+ GF G HC +CP +G C
Sbjct: 745 RCPLGFYGKD--CAL-ICQCQNGADCDHIS---GQCTCRTGFMGRHCEQKCPSGTYGYGC 798
Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCE 130
R+ C C + C+ TG C C GARC+
Sbjct: 799 RQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
Score = 59.3 bits (142), Expect = 1e-08
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 258 GVQCAHSCG-RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG 316
G C C +C H +P+T C+ CEPGW GT C C +G C +C C++G
Sbjct: 102 GEMCVPHCADKCVHGRCIAPNT--CQ-CEPGWGGTNCSSACDGDHWGPHCTSRC-QCKNG 157
Query: 317 EACEPDTGHCQRCSGSR 333
C P TG C +G R
Sbjct: 158 ALCNPITGACHCAAGFR 174
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 234 bits (598), Expect = 2e-61
Identities = 128/373 (34%), Positives = 164/373 (43%), Gaps = 70/373 (18%)
Query: 19 GSELDPK-GQHVCVA--SSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKP-GL 74
G+ DP+ G C A + PS ++ C G C +CQ V P G
Sbjct: 195 GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGF-------FCPSTHSCQNGGVFQTPQGS 247
Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC-------------QCQ 121
C C PG+ G CS CP + GP+C + C CH G C+ TG C +C
Sbjct: 248 CSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECP 307
Query: 122 ADRWGARCEFPCACGPHGRCDPATGVCHCE--------------PGWWSSTCRRPCQCNT 167
R+G C C C P RC PA G C CE G++ +C+ PC C+
Sbjct: 308 VGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDR 367
Query: 168 A-AARCEQATGACVCKPGWWGRRCSFRC-----------NC---HGSPCEQDSGRCACRP 212
+ C G C C PGW G C+ C +C HG C+ SG C C P
Sbjct: 368 EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
Query: 213 GWWGPECQQ-------------QCECVRG-RCSAASGECTCPPGFRGARCELPCPAGSHG 258
G+ GP C +C C CS GEC C G++ C +PCP G+ G
Sbjct: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
Query: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA 318
C SC +C H CSP TG+C +C PGW+G CQ PC G FGE C +C C H +
Sbjct: 488 FSCNASC-QCAHEAVCSPQTGAC-TCTPGWHGAHCQLPCPKGQFGEGCASRCD-CDHSDG 544
Query: 319 CEPDTGHCQRCSG 331
C+P G CQ +G
Sbjct: 545 CDPVHGRCQCQAG 557
Score = 222 bits (565), Expect = 1e-57
Identities = 119/359 (33%), Positives = 152/359 (42%), Gaps = 62/359 (17%)
Query: 27 QHVCVASSPSAELQCCAGW------RQKDQECTIPICEGPDACQKDEVC-VKPGLCRCKP 79
+H + E C GW Q+ P C+ C VC GLC+C P
Sbjct: 368 EHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAP 427
Query: 80 GFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWG 126
G+ G HC+S CP +G +C C C C P G C C+ WG
Sbjct: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
Query: 127 ARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPC-----------QCN-TAAARCEQ 174
C C C C P TG C C PGW + C+ PC +C+ + C+
Sbjct: 488 FSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDP 547
Query: 175 ATGACVCKPGW-------------WGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPECQ 220
G C C+ GW WG CS C C +G C ++G C C PG+ GP CQ
Sbjct: 548 VHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQ 607
Query: 221 QQCE-------CVRGRCS------AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGR 267
+ C+ CV +C+ ++G C C G+ G C PCP G G CA +C +
Sbjct: 608 RSCQPGRYGKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTC-Q 666
Query: 268 CKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
C H C P GSC C GW G C + C GTFG +C Q C C GE C P+TG C
Sbjct: 667 CHHGGTCHPQDGSC-ICPLGWTGHHCLEGCPLGTFGANCSQPC-QCGPGEKCHPETGAC 723
Score = 221 bits (564), Expect = 1e-57
Identities = 121/368 (32%), Positives = 158/368 (42%), Gaps = 70/368 (19%)
Query: 31 VASSPSAELQCCAGWRQKDQECTIPICEG---PDA-----CQKDEVCVK-PGLCRCKPGF 81
V +P C GW C++P EG P+ C +C + G CRC PG+
Sbjct: 240 VFQTPQGSCSCPPGWM--GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297
Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQ--------ADR------WGA 127
G C CP +G DC E+C C P +C PA GAC C+ DR +G
Sbjct: 298 TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGL 357
Query: 128 RCEFPCACGPHGR--CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ----------- 174
C+ PC C C P G C C PGW C C +T C++
Sbjct: 358 SCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQ 417
Query: 175 -ATGACVCKPGW-------------WGRRCSFRCNCHGS-PCEQDSGRCACRPGW----- 214
+G C C PG+ +G CS RC+C + C G C C+ GW
Sbjct: 418 ATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNC 477
Query: 215 --------WGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC 265
WG C C+C CS +G CTC PG+ GA C+LPCP G G CA C
Sbjct: 478 SVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRC 537
Query: 266 GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH 325
C H++ C P G C+ C+ GW G +C C G +G +C C C++G C P+ G+
Sbjct: 538 D-CDHSDGCDPVHGRCQ-CQAGWMGARCHLSCPEGLWGVNCSNTCT-CKNGGTCLPENGN 594
Query: 326 CQRCSGSR 333
C G R
Sbjct: 595 CVCAPGFR 602
Score = 205 bits (521), Expect = 1e-52
Identities = 116/350 (33%), Positives = 152/350 (43%), Gaps = 66/350 (18%)
Query: 39 LQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
LQCC G+ + C +P+C C CV P C+C PG+ G CSS C WGP
Sbjct: 88 LQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCSSECAPGMWGPQ 143
Query: 99 CRESCPCHPHGQCEPATGACQCQA-------------DRWGARCEFPCACGPHGR-CDPA 144
C + C C + C+P +G C C + +G C+F C C HG CDP
Sbjct: 144 CDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC--HGAPCDPQ 201
Query: 145 TGVCHCEPGWWSSTCRRPCQCNTAAARC------------EQATGACVCKPGWWGR---- 188
TG C C +C C T+ C + G+C C PGW G
Sbjct: 202 TGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSL 261
Query: 189 ---------RCSFRCNCH-GSPCEQDSGRCACRPGWWGPECQQQCECVR----------- 227
CS C CH G C++ +G+C C PG+ G C+++C R
Sbjct: 262 PCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDC 321
Query: 228 ---GRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSC 281
RC A+G C C GF G RC + CP G +G+ C C C +H+ C P G C
Sbjct: 322 APDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPC-TCDREHSLSCHPMNGEC 380
Query: 282 ESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSG 331
SC PGW G C + C T G C++ C C HG C+ +G CQ G
Sbjct: 381 -SCLPGWAGLHCNESCPQDTHGPGCQEHC-LCLHGGVCQATSGLCQCAPG 428
Score = 180 bits (457), Expect = 4e-45
Identities = 100/299 (33%), Positives = 124/299 (41%), Gaps = 55/299 (18%)
Query: 31 VASSP-SAELQCCAGWRQKDQECTIPI--------CEGPDACQKDEVCV-KPGLCRCKPG 80
+A SP E C GW++ + C++P C C + VC + G C C PG
Sbjct: 457 IACSPIDGECVCKEGWQRGN--CSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPG 514
Query: 81 FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA-------------DRWGA 127
+ GAHC CP +G C C C C+P G CQCQA WG
Sbjct: 515 WHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGV 574
Query: 128 RCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR-----------CEQAT 176
C C C G C P G C C PG+ +C+R CQ R C +
Sbjct: 575 NCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSN 634
Query: 177 GACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVR-GRCSAASG 235
G C C GW G CS PC PG WG C Q C+C G C G
Sbjct: 635 GTCYCLAGWTGPDCS-------QPCP---------PGHWGENCAQTCQCHHGGTCHPQDG 678
Query: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQ 294
C CP G+ G C CP G+ G C+ C +C E C P+TG+C C PG +G C+
Sbjct: 679 SCICPLGWTGHHCLEGCPLGTFGANCSQPC-QCGPGEKCHPETGAC-VCPPGHSGAPCR 735
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 230 bits (587), Expect = 3e-60
Identities = 124/347 (35%), Positives = 158/347 (45%), Gaps = 61/347 (17%)
Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
QCC G+ + C IP+C + C CV P C C+PG+ G CSS C +WGP C
Sbjct: 87 QCCPGYYESGDFC-IPLCT--EECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR-------------CDPATG 146
C C C P TGAC C A G RCE CA G HG+ CDP G
Sbjct: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAG 202
Query: 147 VCHCEPGWWSSTCRRPCQCNTAAARCE------------QATGACVCKPGW--------- 185
C C PG+ C C + A CE TG C C PGW
Sbjct: 203 ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPC 262
Query: 186 ----WGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPECQQQC-------ECVR------ 227
+G+ CS C C HG C+ +G+C C G+ G CQ++C +C +
Sbjct: 263 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHN 322
Query: 228 -GRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSCGRCKHNE-PCSPDTGSCESC 284
G+CS +G C C PG++G RC E CP G HG C C N C P TG+C +C
Sbjct: 323 GGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGAC-TC 381
Query: 285 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSG 331
+PGW+G C + C G +G+ C+ C C++G C TG C G
Sbjct: 382 QPGWSGHHCNESCPVGYYGDGCQLPCT-CQNGADCHSITGGCTCAPG 427
Score = 218 bits (555), Expect = 2e-56
Identities = 115/331 (34%), Positives = 137/331 (41%), Gaps = 61/331 (18%)
Query: 55 PICEGPDACQKDE-VCVKP--GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC 111
P C P C D + P G C C+PG+ G HC+ CP Y+G C+ C C C
Sbjct: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADC 415
Query: 112 EPATGAC-------------QCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGW---- 154
TG C C A +G C C+C G C P G C C+ GW
Sbjct: 416 HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLD 475
Query: 155 ---------WSSTCRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSF 192
W C C C AA C G+C C PGW +G CS
Sbjct: 476 CTLPCPSGTWGLNCNESCTCANGAA-CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
Query: 193 RCNC-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRG-RCSAASGEC 237
C+C H C+ +G C C GW WGP C C C G CS G C
Sbjct: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594
Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKH-NEPCSPDTGSCESCEPGWNGTQCQQP 296
C PGFRG C+ CP G +G CA C C H + PC +G CE C PG++G C Q
Sbjct: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE-CLPGFSGALCNQV 653
Query: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
C G FG+ C Q C C + C P G CQ
Sbjct: 654 CAGGYFGQDCAQLC-SCANNGTCSPIDGSCQ 683
Score = 205 bits (521), Expect = 1e-52
Identities = 132/451 (29%), Positives = 160/451 (35%), Gaps = 116/451 (25%)
Query: 16 GTQGSELDPKGQHV--CVASSP----------SAELQCCAGWRQKDQECTIPICEGP--D 61
G EL P G H C P + E C GW C P G
Sbjct: 212 GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT--GAVCAQPCPPGTFGQ 269
Query: 62 ACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPA 114
C +D C G C C G+ G C CP +G C + C CH GQC P
Sbjct: 270 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
Query: 115 TGACQCQADRWGARCE--------------FPCACGPHGR--CDPATGVCHCEPGW---- 154
TGAC+C+ G RC+ PC C C P TG C C+PGW
Sbjct: 330 TGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
Query: 155 ---------WSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC-------NC-- 196
+ C+ PC C A C TG C C PG+ G C+ C NC
Sbjct: 390 CNESCPVGYYGDGCQLPCTCQNGAD-CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSS 448
Query: 197 -----HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRGR-CSAASGEC 237
+G C G C C+ GW WG C + C C G CS G C
Sbjct: 449 ICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSC 508
Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPC 297
+C PG+ G CELPCP G+ G+ C+ C C H + C P TG C C GW G +C C
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCD-CSHADGCDPVTGHC-CCLAGWTGIRCDSTC 566
Query: 298 LPGTF------------------------------GESCEQQCPHCRHGEACEPDTGHCQ 327
PG + G C++ CP +G C C
Sbjct: 567 PPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQP---CP 623
Query: 328 RCSGSRDTALIAGSLVPLLLLFLGLACCACC 358
C S + L F G C C
Sbjct: 624 LCVHSSRPCHHISGICECLPGFSGALCNQVC 654
Score = 201 bits (512), Expect = 2e-51
Identities = 112/350 (32%), Positives = 142/350 (40%), Gaps = 69/350 (19%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKP---------GLCRCKPGFFGAHCSSRCP 91
C GW+ D CT+P G +E C G C C PG+ G C CP
Sbjct: 467 CKEGWQGLD--CTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCP 524
Query: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCACGPH 138
+G +C E C C C+P TG C C A RWG C C+C
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584
Query: 139 GRCDPATGVCHCEPGWWSSTCRRPCQ--------------CNTAAARCEQATGACVCKPG 184
G C P G C C PG+ C+R C C ++ C +G C C PG
Sbjct: 585 GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPG 644
Query: 185 -------------WWGRRCSFRCNC-HGSPCEQDSGRCACRPGW-------------WGP 217
++G+ C+ C+C + C G C C PGW WGP
Sbjct: 645 FSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGP 704
Query: 218 ECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP 276
C C C G CSA G C C PG+ G C CPA G C C +C++ C
Sbjct: 705 ACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVC-QCQNGASCDH 763
Query: 277 DTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
+G C +C G+ G C+Q C PGTFG C+Q C C + C+ TG C
Sbjct: 764 ISGKC-TCRTGFTGQHCEQRCAPGTFGYGCQQLC-ECMNNSTCDHVTGTC 811
Score = 196 bits (497), Expect = 9e-50
Identities = 114/391 (29%), Positives = 141/391 (36%), Gaps = 108/391 (27%)
Query: 41 CCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQ 93
C GW + P+ C+ P CQ C G C C PGF G C+ C
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
Query: 94 YWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWGARCEFPCACGPHGR 140
+GP+C C C+ G C P G+C C+ + WG C C C
Sbjct: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500
Query: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGW--- 185
C P G C C PGW TC PC T C + TG C C GW
Sbjct: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
Query: 186 ----------WGRRCSFRCNC----------------------------------HGS-- 199
WG CS C+C HG
Sbjct: 561 RCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQ 620
Query: 200 ----------PCEQDSGRCACRPG-------------WWGPECQQQCECVR-GRCSAASG 235
PC SG C C PG ++G +C Q C C G CS G
Sbjct: 621 PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG 680
Query: 236 ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
C C PG+ G C CP G G C H+C C + CS + G+C C PGW G C Q
Sbjct: 681 SCQCFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGACH-CTPGWTGLFCTQ 738
Query: 296 PCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
C FG+ C + C C++G +C+ +G C
Sbjct: 739 RCPAAFFGKDCGRVC-QCQNGASCDHISGKC 768
Score = 175 bits (444), Expect = 1e-43
Identities = 103/332 (31%), Positives = 131/332 (39%), Gaps = 69/332 (20%)
Query: 32 ASSP-SAELQCCAGWRQKDQECTIPICEGPDACQKDEVC---------VKPGLCRCKPGF 81
A SP C GW C +P +G E C G C C G+
Sbjct: 500 ACSPIDGSCSCTPGWL--GDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGW 557
Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGR- 140
G C S CP WGP+C SC C G C P G+C+C G C+ C G +G
Sbjct: 558 TGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHG 617
Query: 141 --------------CDPATGVCHCEPGWWSSTCRRPCQ-----------CNTAA-ARCEQ 174
C +G+C C PG+ + C + C C+ A C
Sbjct: 618 CAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP 677
Query: 175 ATGACVCKPGW-------------WGRRCSFRCNCH-GSPCEQDSGRCACRPGW------ 214
G+C C PGW WG C C+CH G+ C + G C C PGW
Sbjct: 678 IDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCT 737
Query: 215 -------WGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266
+G +C + C+C G C SG+CTC GF G CE C G+ G C C
Sbjct: 738 QRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLC- 796
Query: 267 RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCL 298
C +N C TG+C C PG+ G +C Q L
Sbjct: 797 ECMNNSTCDHVTGTC-YCSPGFKGIRCDQAAL 827
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 268 CKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
C H SPDT C CEPGW G C C +G C +C C++G C P TG C
Sbjct: 107 CVHGRCVSPDT--CH-CEPGWGGPDCSSGCDSDHWGPHCSNRC-QCQNGALCNPITGACV 162
Query: 328 RCSGSR 333
+G R
Sbjct: 163 CAAGFR 168
Score = 31.2 bits (69), Expect = 3.7
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 297 CLPGTF--GESCEQQCPH-CRHGEACEPDTGHCQRCSGSRD 334
C PG + G+ C C C HG PDT HC+ G D
Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPD 128
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 222 bits (565), Expect = 1e-57
Identities = 119/330 (36%), Positives = 142/330 (43%), Gaps = 59/330 (17%)
Query: 55 PICEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
P CE CQ C G C C G+ G C CP ++G DCR +C C C+
Sbjct: 911 PGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDA 970
Query: 114 ATGACQCQADRWGARC-------------EFPCACGPHGRCDPATGVCHCEPGW------ 154
G+C C A R G RC CAC CDP G CHC PGW
Sbjct: 971 VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCL 1030
Query: 155 -------WSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC------------- 194
+ CR C C C+ +G C C GW G C C
Sbjct: 1031 QACPAGLYGDNCRHSCLCQNGGT-CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSG 1089
Query: 195 NC-HGSPCEQDSGRCACRPGWWGPECQ-------------QQCECVRGR-CSAASGECTC 239
C +G C+ +GRC C GW G +CQ Q+C C G C +G C C
Sbjct: 1090 GCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRC 1149
Query: 240 PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299
PPGF G+ CE CP GS G CA C N C P TG+C SC G++G CQQ C P
Sbjct: 1150 PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC-SCAAGYHGPSCQQRCPP 1208
Query: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
G +G CEQ C C +G +C+ TG C RC
Sbjct: 1209 GRYGPGCEQLC-GCLNGGSCDAATGAC-RC 1236
Score = 214 bits (546), Expect = 2e-55
Identities = 108/295 (36%), Positives = 135/295 (45%), Gaps = 51/295 (17%)
Query: 62 ACQKDEVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ- 119
ACQ C + G C C PGF G+ C CP ++GP C+ C C G C PATG C
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 120 ------------CQADRWGARCEFPCACGP-HGRCDPATGVCHCEPGWWSSTCRRPCQCN 166
C WG C PC C HG CD +G+C CE G+
Sbjct: 848 APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGY------------ 895
Query: 167 TAAARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQDSGRCACRPGW----------- 214
RCEQ C G +G C RC C HG+ C+ SG C C GW
Sbjct: 896 -VGPRCEQQ-----CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPA 949
Query: 215 --WGPECQQQCECVRG-RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHN 271
+G +C+ C C G C A +G C CP G RG RC CPA ++G C+ +C C +
Sbjct: 950 GFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACA-CFNG 1008
Query: 272 EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
C P G C C PGW G C Q C G +G++C C C++G C+P +GHC
Sbjct: 1009 ASCDPVHGQCH-CAPGWMGPSCLQACPAGLYGDNCRHSC-LCQNGGTCDPVSGHC 1061
Score = 209 bits (532), Expect = 7e-54
Identities = 105/280 (37%), Positives = 125/280 (44%), Gaps = 45/280 (16%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA---------- 122
G C C G+ G C RCP +GP C + C C G C+ ATGAC+C
Sbjct: 1189 GTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLT 1248
Query: 123 ---DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ----- 174
R+G C C CG CDP TG C C PG C R C N CE
Sbjct: 1249 CPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCR 1308
Query: 175 -------ATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC-V 226
+ G+C C GW GR C AC PG +G C +C C
Sbjct: 1309 NGGLCHASNGSCSCGLGWTGRHCEL----------------ACPPGRYGAACHLECSCHN 1352
Query: 227 RGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
C A+G C C PGF G CE PCP G HG C C C+H PC P +G C C
Sbjct: 1353 NSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPISGRC-LCPA 1410
Query: 287 GWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
G++G C++ C PG+FGE C Q+C C G C+P TG C
Sbjct: 1411 GFHGHFCERGCEPGSFGEGCHQRC-DCDGGAPCDPVTGLC 1449
Score = 200 bits (508), Expect = 5e-51
Identities = 129/409 (31%), Positives = 157/409 (38%), Gaps = 108/409 (26%)
Query: 23 DPK-GQHVCVASSPSAELQ--CCAGWRQKDQECTIPICEGPDACQKDEVC-VKPGLCRCK 78
DP+ G +C+ + Q C AGW P C+ +C D C G C C
Sbjct: 796 DPETGACLCLPGFVGSRCQDVCPAGWYG-------PSCQTRCSCANDGHCHPATGHCSCA 848
Query: 79 PGFFGAHCSSRCPGQYWGPDCRESCPCHP-HGQCEPATGACQCQADRWGARCEFPCACGP 137
PG+ G C C +WGPDC C C HG C+ +G C C+A G RCE C G
Sbjct: 849 PGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGH 908
Query: 138 HG-------------RCDPATGVCHCEPGWWSSTCRRPCQ-----------CN-TAAARC 172
G CD +G C C GW + C C CN TA A C
Sbjct: 909 FGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC 968
Query: 173 EQATGACVCKPGWWGRRCSFRCNCH--------------GSPCEQDSGRCACRPGWWGPE 218
+ G+C+C G G RC+ C H G+ C+ G+C C PGW GP
Sbjct: 969 DAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPS 1028
Query: 219 CQQ-------------QCECVRG-RCSAASGECTCPPGFRGARCE---LP---------- 251
C Q C C G C SG C CP G+ G CE LP
Sbjct: 1029 CLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHS 1088
Query: 252 -----------------CPAGSHGVQCAHSCGR------------CKHNEPCSPDTGSCE 282
CPAG G +C C R C C TG+C
Sbjct: 1089 GGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACR 1148
Query: 283 SCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSG 331
C PG+ G+ C+Q C PG+FGE C Q C AC P TG C +G
Sbjct: 1149 -CPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAG 1196
Score = 192 bits (487), Expect = 1e-48
Identities = 105/329 (31%), Positives = 134/329 (40%), Gaps = 61/329 (18%)
Query: 61 DACQKDEVCVKPGL--CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGAC 118
D C+ C+ GL C C G+ G C+ CP +G +C SC C G C+ TGAC
Sbjct: 525 DDCRNGGTCLL-GLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
Query: 119 QCQADRWGARCEFPCA-------------CGPHGRCDPATGVCHCEPGWWSSTCR----- 160
+C G CE C C GRC G C C+PG + C
Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 161 --------RPCQC-NTAAARCEQATGACVCKPGWWGRRCSFRCNCH-------------- 197
CQC C++ G+C CK G+ G RC C
Sbjct: 644 WAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
Query: 198 GSPCEQDSGRCA---------------CRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
G C+ SG C C G +G C C C C +G+C CPPG
Sbjct: 704 GVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPG 763
Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
G CE CP G G+ C C C+H C P+TG+C C PG+ G++CQ C G +
Sbjct: 764 RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGAC-LCLPGFVGSRCQDVCPAGWY 822
Query: 303 GESCEQQCPHCRHGEACEPDTGHCQRCSG 331
G SC+ +C C + C P TGHC G
Sbjct: 823 GPSCQTRC-SCANDGHCHPATGHCSCAPG 850
Score = 189 bits (481), Expect = 6e-48
Identities = 108/305 (35%), Positives = 125/305 (40%), Gaps = 48/305 (15%)
Query: 55 PICEGPDACQKDEVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
P CE C C G CRC GF G C+ CP +GP+C C C C+P
Sbjct: 1213 PGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP 1272
Query: 114 ATGACQCQADRWGAR-------------CEFPCACGPHGRCDPATGVC---------HCE 151
TG C C R G R CE C+C G C + G C HCE
Sbjct: 1273 VTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCE 1332
Query: 152 ----PGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGR 207
PG + + C C C+ + CE ATG C C PG++G+ C
Sbjct: 1333 LACPPGRYGAACHLECSCHNNST-CEPATGTCRCGPGFYGQACEH--------------- 1376
Query: 208 CACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266
C PG+ G CQ C C G C SG C CP GF G CE C GS G C C
Sbjct: 1377 -PCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCD 1435
Query: 267 RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
C PC P TG C C PG +G C C G FG SC C C G C+P +G C
Sbjct: 1436 -CDGGAPCDPVTGLC-LCPPGRSGATCNLDCRRGQFGPSCTLHC-DCGGGADCDPVSGQC 1492
Query: 327 QRCSG 331
G
Sbjct: 1493 HCVDG 1497
Score = 137 bits (344), Expect = 5e-32
Identities = 82/259 (31%), Positives = 105/259 (40%), Gaps = 49/259 (18%)
Query: 18 QGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC-VKPGLCR 76
QG+ DP C+ A ++C G Q CE +C+ +C G C
Sbjct: 1266 QGAACDPV-TGTCLCPPGRAGVRCERGCPQNRFGVG---CEHTCSCRNGGLCHASNGSCS 1321
Query: 77 CKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACG 136
C G+ G HC CP +G C C CH + CEPATG C+C +G CE PC G
Sbjct: 1322 CGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPG 1381
Query: 137 PHGR-------------CDPATGVC-------------HCEPGWWSSTCRRPCQCNTAAA 170
HG CDP +G C CEPG + C + C C+ A
Sbjct: 1382 FHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCD-GGA 1440
Query: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR- 229
C+ TG C+C PG G C+ CR G +GP C C+C G
Sbjct: 1441 PCDPVTGLCLCPPGRSGATCNL----------------DCRRGQFGPSCTLHCDCGGGAD 1484
Query: 230 CSAASGECTCPPGFRGARC 248
C SG+C C G+ G C
Sbjct: 1485 CDPVSGQCHCVDGYMGPTC 1503
Score = 120 bits (302), Expect = 4e-27
Identities = 68/202 (33%), Positives = 89/202 (44%), Gaps = 34/202 (16%)
Query: 159 CRRPCQCNTAAARCEQATGACVCKPGW-------------WGRRCSFRCNC-HGSPCEQD 204
C C C C C GW +G+ CSF C+C +G C+
Sbjct: 520 CSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV 579
Query: 205 SGRCACRP-------------GWWGPECQQQCECV-RGRCSAASGECTCPPGFRGARCEL 250
+G C C P G++G C+++C C RGRC G C C PG G C L
Sbjct: 580 TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHL 639
Query: 251 PCPAGSHGVQCAHSCGRC--KHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
CP + G C+ C +C H + C GSC SC+ G+ G +CQ C G FG C Q
Sbjct: 640 TCPPWAFGPGCSEEC-QCVQPHTQSCDKRDGSC-SCKAGFRGERCQAECELGYFGPGCWQ 697
Query: 309 QCPHCRHGEACEPDTGHC-QRC 329
C C G AC+ +G C +RC
Sbjct: 698 ACT-CPVGVACDSVSGECGKRC 718
Score = 78.2 bits (191), Expect = 3e-14
Identities = 103/417 (24%), Positives = 131/417 (31%), Gaps = 118/417 (28%)
Query: 27 QHVCVASSPSAELQCCAGWRQKDQECT---IPICE-GPDACQKD--EVCVKPGLCRCKPG 80
QH CV + S +C G+R T I C G CQ ++ + C+C+PG
Sbjct: 173 QHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPG 232
Query: 81 FF----GAHCSSRCPGQYWGPDCRESCP---------CHPHGQ-------CEP----ATG 116
F G HC R P C C CH Q CE A G
Sbjct: 233 FQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAG 292
Query: 117 ACQCQADRWGARCEFPCAC------GPHGR------------CDPATG------------ 146
QC + F C C G GR C+ G
Sbjct: 293 LAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAG 352
Query: 147 -VCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRC--SFRCNCHGSPCEQ 203
+C C G+ T +R C A C PG + C +R + G CE
Sbjct: 353 PLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCE- 411
Query: 204 DSGRCACRPGWWGPECQQ-----QCECVRGR--------CSAAS-------GECTCP--- 240
D CA G C QC C G CS GE
Sbjct: 412 DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPL 471
Query: 241 PGFRGARCELP----------------------------CPAGSHGVQCAHSCGRCKHNE 272
P + ELP C S G C+ +C C++
Sbjct: 472 PHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGG 531
Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
C C+ C GW G C + C P TFG++C C C++G C+ TG C RC
Sbjct: 532 TCLLGLDGCD-CPEGWTGLICNETCPPDTFGKNCSFSC-SCQNGGTCDSVTGAC-RC 585
Score = 72.8 bits (177), Expect = 1e-12
Identities = 91/398 (22%), Positives = 124/398 (31%), Gaps = 108/398 (27%)
Query: 13 WTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQE--CTIPICEGPDACQKDEVCV 70
W G + + G + L+CC GW Q+ E C C +C
Sbjct: 82 WCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSA-------SLCF 134
Query: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCE 130
G RC P G+ CP + GP C+ + +C G CQ
Sbjct: 135 HGG--RCVP---GSAQPCHCPPGFQGPRCQ-----YDVDECRTHNGGCQ----------- 173
Query: 131 FPCACGPHGRC--DPATGVCHCEPGWWSSTCRRPCQCNTAAA--------RCEQAT---G 177
RC P + +C C+PG+ T R C + A C Q T
Sbjct: 174 --------HRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRH 225
Query: 178 ACVCKPGWW----GRRCSFRCNC--------HGSPCEQDSGRCACRPGWW----GPECQQ 221
C C+PG+ GR C R C H + RC C G+ G C+
Sbjct: 226 RCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 285
Query: 222 QCECVRGRCSAASG--------ECTCPPGFR----GARCEL-------PCPAGSHGVQCA 262
EC G A G +C C G+ G +C C A + G C+
Sbjct: 286 VDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGG--CS 343
Query: 263 HSCGR--------CKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPH-- 312
H C C D +C + + CQQ C G C +
Sbjct: 344 HGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRL 403
Query: 313 ------CRHGEACEPDTG----HCQRCSGSRDTALIAG 340
C + C G HC +GS + AG
Sbjct: 404 SADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAG 441
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 122 bits (306), Expect = 1e-27
Identities = 97/312 (31%), Positives = 124/312 (39%), Gaps = 86/312 (27%)
Query: 26 GQHVCVASSPSAE----LQCCAGWRQKDQECTIPI--CEGPDACQKD---EVCVKPG--- 73
G VCV + E +C AG+ + + P C P + + E CV G
Sbjct: 1876 GSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRT 1935
Query: 74 LCRCKPGFFGAHCSSRCPGQYWGP-----DCRESCPCHPHGQ-------CEPATGACQ-C 120
C CKPG+ GA C PG + P C + C C +G C+P TGAC+ C
Sbjct: 1936 QCLCKPGYAGASCERCAPGFFGNPLVLGSSC-QPCDCSGNGDPNLLFSDCDPLTGACRGC 1994
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAAR-CEQATGAC 179
G RCE CA G +G PG C R C C C+ +G C
Sbjct: 1995 LRHTTGPRCEI-CAPGFYGNA--------LLPG----NCTR-CDCTPCGTEACDPHSGHC 2040
Query: 180 VCKPGWWGRRCSFRCN--------------------CHGSPCEQDSGRCACRPGWWGPEC 219
+CK G GRRC RC GS C SG+C CRPG GP+C
Sbjct: 2041 LCKAGVTGRRCD-RCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQC 2099
Query: 220 QQ--------------QCECVRGRCSAASGECTCPPGFRGARC-------ELPCPAG--S 256
++ +C+C GRC +G C CPPG G RC ++P P G
Sbjct: 2100 RECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVG 2159
Query: 257 HGVQCAHSCGRC 268
H + C C C
Sbjct: 2160 HSIHC-EVCDHC 2170
Score = 120 bits (300), Expect = 6e-27
Identities = 99/343 (28%), Positives = 135/343 (39%), Gaps = 83/343 (24%)
Query: 51 ECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG- 109
+C+ +G +AC+KD + G C CKP F G HC PG ++GP C + C C G
Sbjct: 495 DCSAAGTQG-NACRKDP---RVGRCLCKPNFQGTHCELCAPG-FYGPGC-QPCQCSSPGV 548
Query: 110 ---QCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCN 166
+C+P TG C+C+ GA C+ C P P +C C P
Sbjct: 549 ADDRCDPDTGQCRCRVGFEGATCD---RCAPGYFHFPLCQLCGCSP------------AG 593
Query: 167 TAAARCEQATGACVCKPGWWGRRCSFRC--------NCHGSPCEQ---------DSGRCA 209
T C++A G C+C+P + G C RC NC C+ G C
Sbjct: 594 TLPEGCDEA-GRCLCQPEFAGPHCD-RCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCR 651
Query: 210 CRPGWWGPECQQ------------QCEC-----VRGRCSAASGECTCPPGFRGARCELPC 252
CRPG+ G CQ+ C C + C SG+C+C P G RC+
Sbjct: 652 CRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCV 711
Query: 253 PAGSHGVQC-AHSC--GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG--ESCE 307
P + C A SC +P P+ C G C + C PG +G S
Sbjct: 712 PGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNP 770
Query: 308 QQCPHCR-------HGEA-CEPDTGHC--------QRCSGSRD 334
+ C C G A C+P TG C Q C+ +D
Sbjct: 771 EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKD 813
Score = 108 bits (269), Expect = 2e-23
Identities = 100/350 (28%), Positives = 130/350 (37%), Gaps = 114/350 (32%)
Query: 73 GLC-RCKPGFFGAHCSSRCPGQYWGPD--------CRESCPCHPH---GQCEPATGACQC 120
G+C C+ G +C PG Y P+ CR C C G CE TG C C
Sbjct: 391 GVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRR-CNCESDFTDGTCEDLTGRCYC 449
Query: 121 QADRWGARCE--------FP------------------------CACGPHG------RCD 142
+ + G RC+ FP C C G R D
Sbjct: 450 RPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKD 509
Query: 143 PATGVCHCEPGWWSSTCR-----------RPCQCNT---AAARCEQATGACVCKPGWWGR 188
P G C C+P + + C +PCQC++ A RC+ TG C C+ G+ G
Sbjct: 510 PRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGA 569
Query: 189 RCSFRCN-----------CHGSPCE------QDSGRCACRPGWWGPECQ----------- 220
C RC C SP ++GRC C+P + GP C
Sbjct: 570 TCD-RCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPN 628
Query: 221 -QQCEC-VRG---RCSAASGECTCPPGFRGARCELPCPAGSHG----VQCAHSCGRCKHN 271
Q C C RG + A G C C PG+ G C+ C G HG V C H +
Sbjct: 629 CQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPC-HCSAEGSLH 686
Query: 272 EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEP 321
C P +G C SC P G +C C+PG + P+C G +C P
Sbjct: 687 AACDPRSGQC-SCRPRVTGLRC-DTCVPGAY------NFPYCEAG-SCHP 727
Score = 106 bits (264), Expect = 9e-23
Identities = 95/329 (28%), Positives = 121/329 (36%), Gaps = 61/329 (18%)
Query: 16 GTQGSELDPK-GQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGL 74
G DP GQ C A CA C + C A E C + G
Sbjct: 547 GVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL--CGCSPAGTLPEGCDEAGR 604
Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA---CQCQADRWGARCE- 130
C C+P F G HC PG + P+C ++C C P G + GA C+C+ G C+
Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFPNC-QACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE 663
Query: 131 -----------FPCACGP----HGRCDPATGVCHCEP---GWWSSTCRRPCQCN---TAA 169
PC C H CDP +G C C P G TC P N A
Sbjct: 664 CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC-VPGAYNFPYCEA 722
Query: 170 ARCEQATGACVCKPGWWGRRCSFRCNCH--GSPCEQDSGRCACRPGWWG-----PECQQQ 222
C A G P + C H G C++ C+PG+WG PE +
Sbjct: 723 GSCHPA-GLAPVDPALPEAQVPCMCRAHVEGPSCDR------CKPGFWGLSPSNPEGCTR 775
Query: 223 CEC-VRG------RCSAASGECTCPPGFRGARCELPCPAGSHGVQCA--HSCGRCKHN-- 271
C C +RG C +G+C C P G C C G G+ A C C+ +
Sbjct: 776 CSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCRSCRCDIG 834
Query: 272 ----EPCSPDTGSCESCEPGWNGTQCQQP 296
+ C P TG C C P G C +P
Sbjct: 835 GALGQSCEPRTGVCR-CRPNTQGPTCSEP 862
Score = 100 bits (248), Expect = 6e-21
Identities = 93/345 (26%), Positives = 120/345 (34%), Gaps = 109/345 (31%)
Query: 74 LCRCKPGFFGAHCSSRCPGQY---WGPDCRESCPCHPHG---QCEPATGAC-QCQADRWG 126
LC C + G C PG Y G PC HG +C P +G C CQ + G
Sbjct: 1830 LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 127 ARCE--------------FPCACGPHGRCDPATGV------------CHCEPGWWSSTCR 160
A CE PC P P+ C C+PG+ ++C
Sbjct: 1890 AHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCE 1949
Query: 161 R-----------------PCQC------NTAAARCEQATGAC-------------VCKPG 184
R PC C N + C+ TGAC +C PG
Sbjct: 1950 RCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPG 2009
Query: 185 WWGR-----RCSFRCN---CHGSPCEQDSGRCACRPGWWGPECQ---------------Q 221
++G C+ RC+ C C+ SG C C+ G G C +
Sbjct: 2010 FYGNALLPGNCT-RCDCTPCGTEACDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGCR 2068
Query: 222 QCEC----VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK-HNEPCSP 276
C C C SG+C C PG G +C C G G+ C RC+ C P
Sbjct: 2069 PCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLP-EQGCRRCQCPGGRCDP 2126
Query: 277 DTGSCESCEPGWNGTQC-------QQPCLPGTFGESCE-QQCPHC 313
TG C +C PG +G +C Q P G G S + C HC
Sbjct: 2127 HTGRC-NCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHC 2170
Score = 82.8 bits (203), Expect = 1e-15
Identities = 106/404 (26%), Positives = 133/404 (32%), Gaps = 142/404 (35%)
Query: 56 ICEG-PDACQ-KDEVCVKPGLCRCKPGFFGAHCSSRCPG---QYWGP-------DCRESC 103
+C G DAC KD C C+ G C CPG Q W P +C +SC
Sbjct: 301 VCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANEC-QSC 359
Query: 104 PCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPC 163
C+ H A C D R A GVC C
Sbjct: 360 NCYGH--------ATDCYYDPEVDRRR---ASQSLDGTYQGGGVCI------------DC 396
Query: 164 QCNTAAARCEQATGACVCKPGWWG------------RRCSFRCNCHGSPCEQDSGRCACR 211
Q +T CE+ C PG++ RRC+ + CE +GRC CR
Sbjct: 397 QHHTTGVNCER------CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCR 450
Query: 212 PGWWGPECQQQCECVRG---------------------------RCSAAS---------- 234
P + G C E G CSAA
Sbjct: 451 PNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDP 510
Query: 235 --GECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP------CSPDTGSCESCEP 286
G C C P F+G CEL C G +G C C+ + P C PDTG C C
Sbjct: 511 RVGRCLCKPNFQGTHCEL-CAPGFYG----PGCQPCQCSSPGVADDRCDPDTGQCR-CRV 564
Query: 287 GWNGTQCQQPCLP----------------GTFGESCEQ--QC--------PHCRHGEACE 320
G+ G C + C P GT E C++ +C PHC + C
Sbjct: 565 GFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHC---DRCR 620
Query: 321 P---DTGHCQRCS----GSRDTALIAGSLVPLLLLFLGLACCAC 357
P +CQ C+ G+ D AG L + G AC C
Sbjct: 621 PGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQEC 664
Score = 80.5 bits (197), Expect = 5e-15
Identities = 57/212 (26%), Positives = 73/212 (34%), Gaps = 67/212 (31%)
Query: 103 CPCHPHGQ----CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSST 158
C CH G CEP G C C A G C C G+W
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS------------------RCATGYWGFP 1479
Query: 159 CRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF---------------RCNCHGS---- 199
RPC C A C++ TG C+C P C CNC G
Sbjct: 1480 NCRPCDCG--ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQE 1537
Query: 200 ----PCEQDSGRCACRPGWWGPECQ------------QQCEC-----VRGRCSAASGECT 238
C+ DSG+C CRP G C + C+C G C +G+C
Sbjct: 1538 LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCY 1597
Query: 239 CPPGFRGARCELPCPAGSHGVQCAH--SCGRC 268
C +G +C+ C G+ + A+ C RC
Sbjct: 1598 CKENVQGPKCD-QCSLGTFSLDAANPKGCTRC 1628
Score = 73.2 bits (178), Expect = 8e-13
Identities = 56/179 (31%), Positives = 72/179 (40%), Gaps = 31/179 (17%)
Query: 161 RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG-PEC 219
RPC C+ A TG C+P +C CH +D RCA G+WG P C
Sbjct: 1436 RPCGCHEVGA-----TGP-TCEP------FGGQCPCHAHVIGRDCSRCAT--GYWGFPNC 1481
Query: 220 QQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP------ 273
+ C+C C +G+C CPP C L C + G C C + P
Sbjct: 1482 RP-CDCGARLCDELTGQCICPPRTIPPDC-LLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
Query: 274 ---CSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA---CEPDTGHC 326
C D+G C+ C P G +C C PG G + C G A C+P TG C
Sbjct: 1540 DPTCDTDSGQCK-CRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQC 1596
Score = 71.6 bits (174), Expect = 2e-12
Identities = 71/244 (29%), Positives = 92/244 (37%), Gaps = 45/244 (18%)
Query: 107 PHGQCEPATGA--CQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQ 164
P GQ A+ C C A G C+ C P G G + C PCQ
Sbjct: 1818 PAGQGALASNVELCLCPASYRGDSCQ---ECAP--------GFYRDVKGLFLGRCV-PCQ 1865
Query: 165 CNTAAARCEQATGACV-CKPGWWGRRCSFRCNCHGSPCEQDSG----RCACRPGWWGPEC 219
C+ + RC +G CV C+ G C RC D C C
Sbjct: 1866 CHGHSDRCLPGSGVCVDCQHNTEGAHCE-RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNF 1924
Query: 220 QQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHG--VQCAHSCGRCK---HNEP- 273
+ C GR +C C PG+ GA CE C G G + SC C + +P
Sbjct: 1925 AEGCVLRGGRT-----QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQPCDCSGNGDPN 1978
Query: 274 -----CSPDTGSCESCEPGWNGTQCQQPCLPGTFGE-----SCEQ-QCPHCRHGEACEPD 322
C P TG+C C G +C + C PG +G +C + C C EAC+P
Sbjct: 1979 LLFSDCDPLTGACRGCLRHTTGPRC-EICAPGFYGNALLPGNCTRCDCTPC-GTEACDPH 2036
Query: 323 TGHC 326
+GHC
Sbjct: 2037 SGHC 2040
Score = 66.6 bits (161), Expect = 8e-11
Identities = 68/279 (24%), Positives = 85/279 (30%), Gaps = 96/279 (34%)
Query: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLC 75
GT D G+ +C C C C+ A D++C GLC
Sbjct: 593 GTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGAL--DQLCGAGGLC 650
Query: 76 RCKPGFFGAHCSSRCPGQYWGPDC------------------RESCPCHPH--------- 108
RC+PG+ G C PG + P C C C P
Sbjct: 651 RCRPGYTGTACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTC 710
Query: 109 ------------GQCEPATGA------------CQCQA-------DR-----WGARCEFP 132
G C PA A C C+A DR WG P
Sbjct: 711 VPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNP 770
Query: 133 -----CACGPHG------RCDPATGVCHCEP---GWWSSTCR--------------RPCQ 164
C+C G C P TG C C+P G ++C+ R C+
Sbjct: 771 EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCR 830
Query: 165 CNTAAA---RCEQATGACVCKPGWWGRRCSFRCNCHGSP 200
C+ A CE TG C C+P G CS H P
Sbjct: 831 CDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLP 869
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 11/93 (11%)
Query: 50 QECTIPICEGPDACQ-KDEVC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHP 107
+EC C GP + D C G C+C+P G C + PG + P CR C CH
Sbjct: 1526 EECN---CSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCR-PCDCHE 1581
Query: 108 HGQ----CEPATGACQCQADRWGARCEFPCACG 136
G C+P TG C C+ + G +C+ C+ G
Sbjct: 1582 AGTAPGVCDPLTGQCYCKENVQGPKCD-QCSLG 1613
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 120 bits (300), Expect = 6e-27
Identities = 110/358 (30%), Positives = 133/358 (37%), Gaps = 99/358 (27%)
Query: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFF 82
DP + +S PSA C PD C CV+ G C C PG+
Sbjct: 169 DPTDAEIPPSSPPSASGSC------------------PDDCNDQGRCVR-GRCVCFPGYT 209
Query: 83 GAHCS-SRCPGQ-----------------YWGPDCRE-SCP--CHPHGQCEPATGACQCQ 121
G C CPG + GPDC + SCP C G+CE G C C
Sbjct: 210 GPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCEG--GRCVCD 267
Query: 122 ADRWGARCEF---PCACGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAA-ARCEQAT 176
G C P C GRC+ G C C PG+ C R C + RC+
Sbjct: 268 PGYTGDDCGMRSCPRGCSQRGRCE--NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKD-- 323
Query: 177 GACVCKPGWWGRRCSFRC---NC-HGSPCEQDSGRCACRPGWWGPECQQQC---ECVRGR 229
G CVC PG+ G C R +C G C GRC C PG+ G +C + +C RGR
Sbjct: 324 GRCVCDPGYTGEDCGTRSCPWDCGEGGRCVD--GRCVCWPGYTGEDCSTRTCPRDC-RGR 380
Query: 230 CSAASGECTCPPGFRGARCEL-PCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW 288
GEC C G+ G C + CP G C C + G C C PG+
Sbjct: 381 GRCEDGECICDTGYSGDDCGVRSCP------------GDCNQRGRC--EDGRC-VCWPGY 425
Query: 289 NGTQCQQPCLP------------------GTFGESC-EQQCP-HCRHGEACEPDTGHC 326
GT C P G GE C + CP CR CE +G C
Sbjct: 426 TGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE--SGRC 481
Score = 114 bits (285), Expect = 3e-25
Identities = 102/316 (32%), Positives = 125/316 (39%), Gaps = 70/316 (22%)
Query: 16 GTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLC 75
G + D +G+ C S C G+ +D C C G C+ CV G C
Sbjct: 462 GVRSCPGDCRGRGRC----ESGRCMCWPGYTGRD--CGTRACPGD--CRGRGRCVD-GRC 512
Query: 76 RCKPGFFGAHCSSR-CPGQ-----------------YWGPDCR-ESCP--CHPHGQCEPA 114
C PGF G C SR CPG Y G DC SCP C GQC
Sbjct: 513 VCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQC--L 570
Query: 115 TGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNT-AA 169
G C C+ G C + P C HG C GVC C G+ S C R C N
Sbjct: 571 DGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQD--GVCICWEGYVSEDCSIRTCPSNCHGR 628
Query: 170 ARCEQATGACVCKPGWWGRRCSFR---CNCHG-SPCEQDSGRCACRPGWWGPECQQQ--- 222
RCE+ G C+C PG+ G C+ R +C G C Q G C C G+ G +C Q+
Sbjct: 629 GRCEE--GRCLCDPGYTGPTCATRMCPADCRGRGRCVQ--GVCLCHVGYGGEDCGQEEPP 684
Query: 223 CECVRGRCS----AASGECTCPPGFRGARCEL-PCPAGSHGVQCAHSCGRCKHNEPCSPD 277
G C +G+C C GFRG C + CP G C+ C
Sbjct: 685 ASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCP------------GDCRGRGEC--H 730
Query: 278 TGSCESCEPGWNGTQC 293
GSC C+ G+ G C
Sbjct: 731 DGSC-VCKDGYAGEDC 745
Score = 109 bits (272), Expect = 1e-23
Identities = 105/350 (30%), Positives = 126/350 (36%), Gaps = 82/350 (23%)
Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
+C +C + C G C + C + G C C PG+ G C SR
Sbjct: 387 ECICDTGYSGDDCGVRSCPGD--CNQRGRC-EDGRCVCWPGYTGTDCGSR---------- 433
Query: 100 RESCP--CHPHGQCEPATGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGW 154
+CP C G+CE G C C A G C P C GRC+ +G C C PG+
Sbjct: 434 --ACPRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCE--SGRCMCWPGY 487
Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209
C R G CVC PG+ G RRC C HG CE G C
Sbjct: 488 TGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGL-CE--DGVCV 544
Query: 210 CRPGWWGPECQQQCEC---VRGRCSAASGECTCPPGFRGARC---ELPCPAGSHGVQCAH 263
C G+ G +C + C RGR G C C G+ G C + P HGV C
Sbjct: 545 CDAGYSGEDCSTR-SCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGV-CQD 602
Query: 264 S---CGRCKHNEPCSPDT--------GSCES----CEPGWNGTQC--------------- 293
C +E CS T G CE C+PG+ G C
Sbjct: 603 GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662
Query: 294 -QQPCL--PGTFGESCEQQ------CP-HCRHGEACEPDTGHCQRCSGSR 333
Q CL G GE C Q+ CP C E C G C G R
Sbjct: 663 VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR--AGQCVCVEGFR 710
Score = 97.4 bits (241), Expect = 4e-20
Identities = 83/277 (29%), Positives = 104/277 (37%), Gaps = 73/277 (26%)
Query: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCN-------TA 168
G C A + + C HG D + C CEPGW TC P +A
Sbjct: 124 GCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSA 183
Query: 169 AARCEQ--------ATGACVCKPGWWGRRCSFRC---NCHG-SPCEQDSGRCACRPGWWG 216
+ C G CVC PG+ G C + +C G C Q G C CR G+ G
Sbjct: 184 SGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQ--GVCVCRAGFSG 241
Query: 217 PECQQQCECVRG---RCSAASGECTCPPGFRGARCEL-PCPAG-SHGVQCAHSCGRCKHN 271
P+C Q+ C RG R G C C PG+ G C + CP G S +C + GRC N
Sbjct: 242 PDCSQR-SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCEN--GRCVCN 298
Query: 272 -----EPCS--------PDTGSCES----CEPGWNGTQC------------------QQP 296
E C G C+ C+PG+ G C +
Sbjct: 299 PGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCV 358
Query: 297 CLPGTFGESCE-QQCP-------HCRHGEACEPDTGH 325
C PG GE C + CP C GE C DTG+
Sbjct: 359 CWPGYTGEDCSTRTCPRDCRGRGRCEDGE-CICDTGY 394
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 119 bits (299), Expect = 8e-27
Identities = 79/252 (31%), Positives = 105/252 (41%), Gaps = 50/252 (19%)
Query: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ 119
P C + CV G+C C PGF GA C+ + +CP G + + G CQ
Sbjct: 577 PRNCHGNGECVS-GVCHCFPGFLGADCA------------KAACPVLCSGNGQYSKGTCQ 623
Query: 120 CQADRWGARCEFPC------ACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAARC 172
C + GA C+ P +CG HG C G C C G+ C C T ++
Sbjct: 624 CYSGWKGAECDVPMNQCIDPSCGGHGSC--IDGNCVCSAGYKGEHCEEVDCLDPTCSSHG 681
Query: 173 EQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ--- 222
G C+C PGW G C +C+ HG+ D+G C+C P W GP+C +
Sbjct: 682 VCVNGECLCSPGWGGLNCELARVQCPDQCSGHGTYL-PDTGLCSCDPNWMGPDCSVEVCS 740
Query: 223 CEC-VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281
+C G C G C C G+ GA C+ + H RC + C G C
Sbjct: 741 VDCGTHGVC--IGGACRCEEGWTGAACD---------QRVCHP--RCIEHGTCK--DGKC 785
Query: 282 ESCEPGWNGTQC 293
E C GWNG C
Sbjct: 786 E-CREGWNGEHC 796
Score = 108 bits (269), Expect = 2e-23
Identities = 81/250 (32%), Positives = 99/250 (39%), Gaps = 43/250 (17%)
Query: 40 QCCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
QC +GW K EC +P+ + D +C C+ G C C G+ G HC D
Sbjct: 623 QCYSGW--KGAECDVPMNQCIDPSCGGHGSCID-GNCVCSAGYKGEHCEE--------VD 671
Query: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEF-----PCACGPHGRCDPATGVCHCEPG 153
C + C HG C G C C G CE P C HG P TG+C C+P
Sbjct: 672 CLDPT-CSSHGVC--VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPN 728
Query: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRC 208
W C GAC C+ GW G R C RC HG+ C+ G+C
Sbjct: 729 WMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGT-CK--DGKC 785
Query: 209 ACRPGWWGPECQ-QQCECV---RGRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCA 262
CR GW G C C + GRC+ S +C C G+RG C V
Sbjct: 786 ECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQTGWRGPGC---------NVAME 836
Query: 263 HSCGRCKHNE 272
SC K NE
Sbjct: 837 TSCADNKDNE 846
Score = 99.4 bits (246), Expect = 1e-20
Identities = 66/225 (29%), Positives = 90/225 (40%), Gaps = 44/225 (19%)
Query: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
C HG + +GVCHC PG+ + C + + + + G C C GW G C
Sbjct: 576 CPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDV 635
Query: 193 --------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSA----ASGECTCP 240
C HGS + G C C G+ G C ++ +C+ CS+ +GEC C
Sbjct: 636 PMNQCIDPSCGGHGSCID---GNCVCSAGYKGEHC-EEVDCLDPTCSSHGVCVNGECLCS 691
Query: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP---- 296
PG+ G CEL VQC +C + PDTG C SC+P W G C
Sbjct: 692 PGWGGLNCELA------RVQCP---DQCSGHGTYLPDTGLC-SCDPNWMGPDCSVEVCSV 741
Query: 297 --------------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
C G G +C+Q+ H R E G C+
Sbjct: 742 DCGTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCE 786
Score = 55.8 bits (133), Expect = 1e-07
Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 30/150 (20%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR 100
C W D C++ +C C VC+ G CRC+ G+ GA C R
Sbjct: 725 CDPNWMGPD--CSVEVCSVD--CGTHGVCIG-GACRCEEGWTGAACDQRV---------- 769
Query: 101 ESCPCHP----HGQCEPATGACQCQADRWGARCEF---PCACGPHGRCDPATGV--CHCE 151
CHP HG C+ G C+C+ G C P C +GRC C C+
Sbjct: 770 ----CHPRCIEHGTCKD--GKCECREGWNGEHCTIDGCPDLCNGNGRCTLGQNSWQCVCQ 823
Query: 152 PGWWSSTCRRPCQCNTAAARCEQATGACVC 181
GW C + + A + + G C
Sbjct: 824 TGWRGPGCNVAMETSCADNKDNEGDGLVDC 853
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 118 bits (296), Expect = 2e-26
Identities = 91/306 (29%), Positives = 113/306 (36%), Gaps = 51/306 (16%)
Query: 54 IPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQY-WGPDCRESCPCHPHGQ-- 110
+P P E G C CKPG G C PG Y +GP ++C C G
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840
Query: 111 --CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA 168
CE +G C C+ +G RC+ C+ G W RPC CN
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCD------------------RCQRGQWGFPSCRPCVCNGH 882
Query: 169 AARCEQATGACV-CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQ--C 223
A C TGAC+ C+ G C RC HG P G+C P GP Q+
Sbjct: 883 ADECNTHTGACLGCRDHTGGEHCE-RCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFAT 941
Query: 224 ECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK-----------HNE 272
C + S C C G+ G RCE P H + GRC+ +
Sbjct: 942 SCHQDEYSQQI-VCHCRAGYTGLRCEACAP--GHFGDPSRPGGRCQLCECSGNIDPMDPD 998
Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHC------RHGEAC-EPDTGH 325
C P TG C C G C C PG G++ Q C C + + C PD H
Sbjct: 999 ACDPHTGQCLRCLHHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH 1057
Query: 326 CQRCSG 331
C SG
Sbjct: 1058 CDPSSG 1063
Score = 105 bits (263), Expect = 1e-22
Identities = 118/420 (28%), Positives = 146/420 (34%), Gaps = 123/420 (29%)
Query: 15 RGTQGSELDPKG-QHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKP- 72
+G+ SE +P G Q +C CA C+ +C K
Sbjct: 788 QGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTS 847
Query: 73 GLCRCKPGFFGAHCSSRCPGQYWG-PDCRESCPCHPHG-QCEPATGACQ-CQADRWGARC 129
G C C+ G FG C RC WG P CR C C+ H +C TGAC C+ G C
Sbjct: 848 GQCLCRTGAFGLRCD-RCQRGQWGFPSCRP-CVCNGHADECNTHTGACLGCRDHTGGEHC 905
Query: 130 EF------------------PCAC--GPHGRCDPATG----------VCHCEPGWWSSTC 159
E PC C GP + AT VCHC G+ C
Sbjct: 906 ERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRC 965
Query: 160 R-----------RP------CQCN-----TAAARCEQATGACV-------------CKPG 184
RP C+C+ C+ TG C+ CKPG
Sbjct: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
Query: 185 WWG---RRCSFRCNCH---------GSP----CEQDSGRCACRPGWWGPECQ-------- 220
+ G R+ RC C+ SP C+ SG+C C P GP C
Sbjct: 1026 FHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWN 1085
Query: 221 -------QQCECVRGR-----CSAASGECTCPPGFRGARCELPCPA---GSHGVQCAHSC 265
Q C C R C+ +G+C C GF G C C G G+QC H+C
Sbjct: 1086 LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQC-HAC 1143
Query: 266 ---GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPD 322
R C TG C SC PG +G +C Q C G G P C AC D
Sbjct: 1144 DCDSRGIDTPQCHRFTGHC-SCRPGVSGVRCDQ-CARGFSG-----IFPACHPCHACFGD 1196
Score = 63.5 bits (153), Expect = 7e-10
Identities = 68/258 (26%), Positives = 90/258 (34%), Gaps = 93/258 (36%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQY----WGPD-------CRESCPCHPHGQC---------- 111
G C CK G +C +C Y W P CR+ C CH H
Sbjct: 308 GACICKHNTRGLNCE-QCQDFYRDLPWRPAEDGHSHACRK-CECHGHTHSCHFDMAVYLA 365
Query: 112 --EPATGACQ-CQADRWGARCEF--------------------PCACGPHGRCDPATGVC 148
+ G C CQ + G CE C C P G D
Sbjct: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDS 425
Query: 149 HCEP--GWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG---------RRCSFRCNCH 197
H +P G S CR C+ + RC+Q C+ G++G RRC +CN
Sbjct: 426 HDDPALGLVSGQCR--CKEHVVGTRCQQ------CRDGFFGLSISDRLGCRRC--QCNAR 475
Query: 198 GS-----PCEQDSGRCACR------------PGWWGPECQ----QQCECVRG-----RCS 231
G+ PC+ +SG C C+ PG WG + C+C G +C
Sbjct: 476 GTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCD 535
Query: 232 AASGECTCPPGFRGARCE 249
+G+C C G RCE
Sbjct: 536 EGTGQCHCRQHMVGRRCE 553
Score = 58.5 bits (140), Expect = 2e-08
Identities = 53/185 (28%), Positives = 71/185 (38%), Gaps = 65/185 (35%)
Query: 70 VKPGLCR-CKPGFFGAHCSSRCPGQYWGP--DCRE-----SCPCHPHG-----QCE---- 112
V G+C C+ G HC P Y P D R+ SC C P G +C+
Sbjct: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428
Query: 113 PA----TGACQCQADRWGARCEF-----------------PCACGPHGR------CDPAT 145
PA +G C+C+ G RC+ C C G CDP +
Sbjct: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
Query: 146 GVCHCE------------PGWWSST-----CRRPCQCNTAAA---RCEQATGACVCKPGW 185
G C+C+ PG W + CR PC C+ A +C++ TG C C+
Sbjct: 489 GSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR-PCDCDVGGALDPQCDEGTGQCHCRQHM 547
Query: 186 WGRRC 190
GRRC
Sbjct: 548 VGRRC 552
Score = 40.0 bits (92), Expect = 0.008
Identities = 55/215 (25%), Positives = 72/215 (33%), Gaps = 51/215 (23%)
Query: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGP-- 217
R C C A+ C A GA G C + N G CEQ P W P
Sbjct: 280 RGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLP--WRPAE 337
Query: 218 ----ECQQQCECVRGRCSA--------ASGECT------CPPGFRGARCELPCP----AG 255
++CEC S ASG + C G CEL P
Sbjct: 338 DGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDP 397
Query: 256 SHGVQCAHSCGRCKHNEPCSPDTGSCES--------------CEPGWNGTQCQQPCLPGT 301
+ ++ C C + S D G C+S C+ GT+CQQ C G
Sbjct: 398 TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGF 456
Query: 302 FGESCEQQ--CPHCR--------HGEACEPDTGHC 326
FG S + C C+ C+P++G C
Sbjct: 457 FGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC 491
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 118 bits (296), Expect = 2e-26
Identities = 91/282 (32%), Positives = 106/282 (37%), Gaps = 67/282 (23%)
Query: 56 ICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCP------GQY----------W-GP 97
+ E P C + CV G C C PGF G CS + CP GQY W G
Sbjct: 515 VVECPRNCHGNGECVS-GTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGT 573
Query: 98 DC---RESC---PCHPHGQCEPATGACQCQADRWGARCE----FPCACGPHGRCDPATGV 147
+C C C G C G+C C + G CE C HG C G
Sbjct: 574 ECDVPTTQCIDPQCGGRGIC--IMGSCACNSGYKGESCEEADCIDPGCSNHGVC--IHGE 629
Query: 148 CHCEPGWWSSTCR-----RPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCH 197
CHC PGW S C P QC+ Q +G+C C P W G CS C H
Sbjct: 630 CHCSPGWGGSNCEILKTMCPDQCSGHGTYL-QESGSCTCDPNWTGPDCSNEICSVDCGSH 688
Query: 198 GSPCEQDSGRCACRPGWWGPECQQQC---ECV-RGRCSAASGECTCPPGFRGARCELP-C 252
G G C C GW GP C Q+ C G C G+C C G+ G C + C
Sbjct: 689 GVCM---GGTCRCEEGWTGPACNQRACHPRCAEHGTCK--DGKCECSQGWNGEHCTIEGC 743
Query: 253 PAGSHGVQCAHSCGRCKHNEPCSPDTGSCES-CEPGWNGTQC 293
P G C N C+ D C+PGW G C
Sbjct: 744 P------------GLCNSNGRCTLDQNGWHCVCQPGWRGAGC 773
Score = 97.4 bits (241), Expect = 4e-20
Identities = 69/236 (29%), Positives = 92/236 (38%), Gaps = 41/236 (17%)
Query: 22 LDPK--GQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
+DP+ G+ +C+ S C K + C C P C VC+ G C C P
Sbjct: 583 IDPQCGGRGICIMGS------CACNSGYKGESCEEADCIDP-GCSNHGVCIH-GECHCSP 634
Query: 80 GFFGAHCS---SRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-- 134
G+ G++C + CP Q C HG +G+C C + G C
Sbjct: 635 GWGGSNCEILKTMCPDQ-----------CSGHGTYLQESGSCTCDPNWTGPDCSNEICSV 683
Query: 135 -CGPHGRCDPATGVCHCEPGWWSSTC-RRPCQCNTAA-ARCEQATGACVCKPGWWGRRCS 191
CG HG C G C CE GW C +R C A C+ G C C GW G C+
Sbjct: 684 DCGSHGVC--MGGTCRCEEGWTGPACNQRACHPRCAEHGTCKD--GKCECSQGWNGEHCT 739
Query: 192 FR-----CNCHGS-PCEQDSGRCACRPGWWGPECQQQCE--CVRGRCSAASGECTC 239
CN +G +Q+ C C+PGW G C E C + + G C
Sbjct: 740 IEGCPGLCNSNGRCTLDQNGWHCVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDC 795
Score = 93.2 bits (230), Expect = 8e-19
Identities = 74/242 (30%), Positives = 96/242 (39%), Gaps = 53/242 (21%)
Query: 130 EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRR 189
E P C +G C +G CHC PG+ C R + + + G C+C GW G
Sbjct: 517 ECPRNCHGNGEC--VSGTCHCFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTE 574
Query: 190 CSF-RCNCHGSPCEQDS----GRCACRPGWWGPECQQQCECVRGRCS----AASGECTCP 240
C C C G CAC G+ G C ++ +C+ CS GEC C
Sbjct: 575 CDVPTTQCIDPQCGGRGICIMGSCACNSGYKGESC-EEADCIDPGCSNHGVCIHGECHCS 633
Query: 241 PGFRGARCEL-----PCPAGSHG--VQCAHSC-------GRCKHNEPCSPDTGS------ 280
PG+ G+ CE+ P HG +Q + SC G NE CS D GS
Sbjct: 634 PGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCMG 693
Query: 281 --CESCEPGWNGTQCQQPCLPGTFGESCEQQCPH---CRHGEACEPDTG----HC--QRC 329
C CE GW G C Q +C +C C+ G+ CE G HC + C
Sbjct: 694 GTCR-CEEGWTGPACNQ--------RACHPRCAEHGTCKDGK-CECSQGWNGEHCTIEGC 743
Query: 330 SG 331
G
Sbjct: 744 PG 745
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 118 bits (295), Expect = 2e-26
Identities = 95/285 (33%), Positives = 121/285 (42%), Gaps = 70/285 (24%)
Query: 50 QECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS-RCPGQYWGPDCRESCPCHPH 108
++C P C P AC C + G C C GF G CS RCP CH
Sbjct: 339 EDCGKPTC--PHACHTQGRC-EEGQCVCDEGFAGVDCSEKRCPAD-----------CHNR 384
Query: 109 GQCEPATGACQCQADRWGARC---EFPCACGPHGRCDPATGVCHCEPGWWSSTC---RRP 162
G+C G C+C GA C + P C HGRC G C C+ G+ C R P
Sbjct: 385 GRC--VDGRCECDDGFTGADCGELKCPNGCSGHGRC--VNGQCVCDEGYTGEDCSQLRCP 440
Query: 163 CQCNTAAARCEQATGACVCKPGWWGRRCSFR-----CNCHGSPCEQDSGRCACRPGWWGP 217
C++ RC + G CVC+ G+ G CS C+ HG +G C C G+ G
Sbjct: 441 NDCHSRG-RCVE--GKCVCEQGFKGYDCSDMSCPNDCHQHGRCV---NGMCVCDDGYTGE 494
Query: 218 ECQ-QQC--ECV-RGRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSCGRCKHNE 272
+C+ +QC +C RG C G+C C GF G C EL CP HG GRC +
Sbjct: 495 DCRDRQCPRDCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHGQ------GRCVN-- 544
Query: 273 PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGE 317
G C C G+ G C+ EQ+CP HG+
Sbjct: 545 ------GQC-VCHEGFMGKDCK------------EQRCPSDCHGQ 570
Score = 109 bits (273), Expect = 8e-24
Identities = 95/297 (31%), Positives = 123/297 (41%), Gaps = 49/297 (16%)
Query: 24 PKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFG 83
P H C E QC +C+ C P C CV G C C GF G
Sbjct: 344 PTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRC--PADCHNRGRCVD-GRCECDDGFTG 400
Query: 84 AHCSS-RCP-----------GQ------YWGPDCRE-SCP--CHPHGQCEPATGACQCQA 122
A C +CP GQ Y G DC + CP CH G+C G C C+
Sbjct: 401 ADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRC--VEGKCVCEQ 458
Query: 123 DRWGARCE---FPCACGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCNTAAARCEQATGA 178
G C P C HGRC G+C C+ G+ CR R C + R G
Sbjct: 459 GFKGYDCSDMSCPNDCHQHGRC--VNGMCVCDDGYTGEDCRDRQCP-RDCSNRGLCVDGQ 515
Query: 179 CVCKPGWWGRRCS-FRC--NCHGSPCEQDSGRCACRPGWWGPECQQQ---CECV-RGRCS 231
CVC+ G+ G C+ C +CHG +G+C C G+ G +C++Q +C +GRC
Sbjct: 516 CVCEDGFTGPDCAELSCPNDCHGQG-RCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC- 573
Query: 232 AASGECTCPPGFRGARC-ELPCPAGSHGV-QCAHSCGRCKHNEPCSPDTGSCESCEP 286
G+C C GF G C + CP+ + + QC GRC NE S + C P
Sbjct: 574 -VDGQCICHEGFTGLDCGQHSCPSDCNNLGQCV--SGRCICNEGYSGE--DCSEVSP 625
Score = 103 bits (257), Expect = 6e-22
Identities = 93/309 (30%), Positives = 113/309 (36%), Gaps = 74/309 (23%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS-RCPGQYWGPDC 99
C GW K C+ P C P C C+ G C C GF G CS CP
Sbjct: 176 CEPGW--KGPNCSEPEC--PGNCHLRGRCID-GQCICDDGFTGEDCSQLACPSD------ 224
Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCE-----FPCACGPHGRCDPATGVCHCEPGW 154
C+ G+C G C C GA C PC+ HG C G+C C G+
Sbjct: 225 -----CNDQGKC--VNGVCICFEGYAGADCSREICPVPCS-EEHGTC--VDGLCVCHDGF 274
Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQD---SGRCACR 211
C +P N R CVC G+ G CS C ++ +G C C
Sbjct: 275 AGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCS-ELICPNDCFDRGRCINGTCYCE 333
Query: 212 PGWWG-----PECQQQCECVRGRCSAASGECTCPPGFRGARC-ELPCPAGSHGVQCAHSC 265
G+ G P C C +GRC G+C C GF G C E CPA H+
Sbjct: 334 EGFTGEDCGKPTCPHACH-TQGRCE--EGQCVCDEGFAGVDCSEKRCPAD------CHNR 384
Query: 266 GRCKHNEPCSPDTGSCESCEPGWNGTQC------------------QQPCLPGTFGESCE 307
GRC G CE C+ G+ G C Q C G GE C
Sbjct: 385 GRCV--------DGRCE-CDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCS 435
Query: 308 Q-QCPHCRH 315
Q +CP+ H
Sbjct: 436 QLRCPNDCH 444
Score = 76.3 bits (186), Expect = 1e-13
Identities = 76/270 (28%), Positives = 90/270 (33%), Gaps = 63/270 (23%)
Query: 110 QCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAA 169
QC G C A R + C G C CEPGW C P
Sbjct: 139 QCTAGAGCCLQPAT---GRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCH 195
Query: 170 ARCEQATGACVCKPGWWGRRCS-----FRCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222
R G C+C G+ G CS CN G +G C C G+ G +C ++
Sbjct: 196 LRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCV---NGVCICFEGYAGADCSREIC 252
Query: 223 ---CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC---GRCKHN----- 271
C G C G C C GF G C P C ++C GRC N
Sbjct: 253 PVPCSEEHGTC--VDGLCVCHDGFAGDDCNKPL--------CLNNCYNRGRCVENECVCD 302
Query: 272 -----EPCSP--------DTGSCES----CEPGWNGTQCQQPCLP---GTFGESCEQQCP 311
E CS D G C + CE G+ G C +P P T G E QC
Sbjct: 303 EGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCV 362
Query: 312 HCRHGEA--------CEPDTGHCQRCSGSR 333
C G A C D + RC R
Sbjct: 363 -CDEGFAGVDCSEKRCPADCHNRGRCVDGR 391
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 115 bits (287), Expect = 2e-25
Identities = 80/252 (31%), Positives = 100/252 (39%), Gaps = 50/252 (19%)
Query: 60 PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC-RESCPCHPHGQCEPATGAC 118
P C + C+ G C C GF G PDC R SCP G + G C
Sbjct: 567 PSNCYGNGDCIS-GTCHCFLGFLG-------------PDCGRASCPVLCSGNGQYMKGRC 612
Query: 119 QCQADRWGARCEFP------CACGPHGRCDPATGVCHCEPGWWSSTCRR-PCQCNTAAAR 171
C + GA C+ P AC HG C TG C C PG+ +C C T + R
Sbjct: 613 LCHSGWKGAECDVPTNQCIDVACSNHGTC--ITGTCICNPGYKGESCEEVDCMDPTCSGR 670
Query: 172 CEQATGACVCKPGWWGRRCSF-------RCNCHGSPCEQDSGRCACRPGWWGPECQQQ-- 222
G C C GW G C +C+ HG+ D+G C+C P W G +C +
Sbjct: 671 GVCVRGECHCSVGWGGTNCETPRATCLDQCSGHGT-FLPDTGLCSCDPSWTGHDCSIEIC 729
Query: 223 -CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSC 281
+C G G C C G+ GA C+ + H RC + C G C
Sbjct: 730 AADC-GGHGVCVGGTCRCEDGWMGAACD---------QRACHP--RCAEHGTCR--DGKC 775
Query: 282 ESCEPGWNGTQC 293
E C PGWNG C
Sbjct: 776 E-CSPGWNGEHC 786
Score = 105 bits (263), Expect = 1e-22
Identities = 78/258 (30%), Positives = 97/258 (37%), Gaps = 52/258 (20%)
Query: 41 CCAGWRQKDQECTIPICEGPD-ACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
C +GW K EC +P + D AC C+ G C C PG+ G C DC
Sbjct: 614 CHSGW--KGAECDVPTNQCIDVACSNHGTCIT-GTCICNPGYKGESCEE--------VDC 662
Query: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-----CGPHGRCDPATGVCHCEPGW 154
+ C G C G C C G CE P A C HG P TG+C C+P W
Sbjct: 663 MDP-TCSGRGVC--VRGECHCSVGWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSW 719
Query: 155 WSSTCRRPCQCNTAAARCEQATGACVCKPGWWG-----RRCSFRCNCHGSPCEQDSGRCA 209
C G C C+ GW G R C RC HG+ C G+C
Sbjct: 720 TGHDCSIEICAADCGGHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGT-CR--DGKCE 776
Query: 210 CRPGWWGPEC----------QQQCECV---RGRCS--AASGECTCPPGFRGARCELPCPA 254
C PGW G C ++ C + GRC+ C C G+RGA C+
Sbjct: 777 CSPGWNGEHCTIAHYLDRVVKEGCPGLCNGNGRCTLDLNGWHCVCQLGWRGAGCD----- 831
Query: 255 GSHGVQCAHSCGRCKHNE 272
+CG K N+
Sbjct: 832 ----TSMETACGDSKDND 845
Score = 92.4 bits (228), Expect = 1e-18
Identities = 64/225 (28%), Positives = 84/225 (37%), Gaps = 39/225 (17%)
Query: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
C +G D +G CHC G+ C R + + G C+C GW G C
Sbjct: 566 CPSNCYGNGDCISGTCHCFLGFLGPDCGRASCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 193 RCN-CHGSPCEQD----SGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPGF 243
N C C +G C C PG+ G C ++ +C+ CS GEC C G+
Sbjct: 626 PTNQCIDVACSNHGTCITGTCICNPGYKGESC-EEVDCMDPTCSGRGVCVRGECHCSVGW 684
Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP------- 296
G CE P A +C + PDTG C SC+P W G C
Sbjct: 685 GGTNCETP---------RATCLDQCSGHGTFLPDTGLC-SCDPSWTGHDCSIEICAADCG 734
Query: 297 -----------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCS 330
C G G +C+Q+ H R E G C+ CS
Sbjct: 735 GHGVCVGGTCRCEDGWMGAACDQRACHPRCAEHGTCRDGKCE-CS 778
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 114 bits (284), Expect = 4e-25
Identities = 104/411 (25%), Positives = 143/411 (34%), Gaps = 99/411 (24%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC---VKPGLCRCKPGFFGAHC 86
C+ + S E QC G+ E + C + CQ D C + C C PG+ G HC
Sbjct: 429 CINTLGSFECQCLQGYTGPRCEIDVNECVS-NPCQNDATCLDQIGEFQCICMPGYEGVHC 487
Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF--------PCACG 136
+C S PC +G+C C+C G C++ PC G
Sbjct: 488 EVNTD------ECASS-PCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG 540
Query: 137 PHGRCDPATGVCHCEPGWWSSTCR------RPCQCNTAAARCEQATGACVCKPGWWGRRC 190
P T C C G+ + C P C+ + + AT C+C+PG+ G C
Sbjct: 541 AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC 600
Query: 191 SFRCN-CHGSPCE-----QDSGR---CACRPGWWGPECQQQC-ECVRGRCSAAS------ 234
N C PC QD C C G GP C+ +C C + +
Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID 660
Query: 235 -GECTCPPGFRGARCEL-------------------------PCPAGSHGVQCAHSCGRC 268
EC C PG+ G+ C + CP G H C C
Sbjct: 661 GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC 720
Query: 269 KHNEPCSPDTGSCE--------SCEPGWNGTQC--------QQPCLPG------TFGESC 306
N PC G+C C+PGW+GT C PC+ G T G C
Sbjct: 721 NSN-PCV--HGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC 777
Query: 307 EQQCPHCRHGEACEPDTGHC-QRCSGSRDTAL--IAGSLVPLLLLFLGLAC 354
C G C+ + C ++ T + +AG LL + G C
Sbjct: 778 --TCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATC 826
Score = 98.6 bits (244), Expect = 2e-20
Identities = 89/319 (27%), Positives = 113/319 (35%), Gaps = 75/319 (23%)
Query: 59 GPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE-----SCPCHPHGQCE- 112
GP Q E C+ G C G C G + GP C++ S PC G C
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCG----GAFVGPRCQDPNPCLSTPCKNAGTCHV 76
Query: 113 -----PATGACQCQADRWGARCEFPC-------ACGPHGRCDPATGV---CHCEPGWWSS 157
A AC C G C P C G CD T C C PGW
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGK 136
Query: 158 TCRR--PCQCNTAA--ARC--EQATGACVCKPGWWGRRCSFRCN-C--------HGSPCE 202
+C++ PC N A +C +A+ C C P + G C N C HG C
Sbjct: 137 SCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH 196
Query: 203 QDSG--RCACRPGWWGPECQQ------QCECVRGRCSAASG----ECTCPPGFRGARCEL 250
+ G RC CR GP C++ C G +G EC C PGF G CE
Sbjct: 197 NEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
Query: 251 ---PCPAGSHGVQCAHSCGRCKHNEPC--SPDTGSCESCEPGWNGTQCQQPCLPGTFGES 305
CP + CK+ C +T +C C P W G C + +
Sbjct: 257 NIDDCPGNN-----------CKNGGACVDGVNTYNCR-CPPEWTGQYCTEDV------DE 298
Query: 306 CEQQCPHCRHGEACEPDTG 324
C+ C++G C G
Sbjct: 299 CQLMPNACQNGGTCHNTHG 317
Score = 97.8 bits (242), Expect = 3e-20
Identities = 100/363 (27%), Positives = 128/363 (35%), Gaps = 91/363 (25%)
Query: 22 LDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQ----KDEVCVKPGLCRC 77
LD + CV C G+ E I C+ PD C KD V C C
Sbjct: 544 LDGPNTYTCV---------CTEGYTGTHCEVDIDECD-PDPCHYGSCKDGVATFT--CLC 591
Query: 78 KPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF---P 132
+PG+ G HC + +C S PC G C+ A C C G CE
Sbjct: 592 RPGYTGHHCETNIN------EC-SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD 644
Query: 133 CACGPHGRCDPATGV-------CHCEPGWWSSTCR--------RPCQCNTAAARCEQATG 177
CA P CD T + C CEPG+ S C PC CE
Sbjct: 645 CASSP---CDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCH---NGGTCEDGIN 698
Query: 178 A--CVCKPGWWGRRCSFRCN-CHGSPCEQDSGR-------CACRPGWWGPECQ---QQCE 224
C C G+ C N C+ +PC + R C C PGW G C +CE
Sbjct: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECE 758
Query: 225 ---CVRG---RCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDT 278
CV G + + CTC GF G C+ ++ +CA + C + C D
Sbjct: 759 SNPCVNGGTCKDMTSGYVCTCREGFSGPNCQ------TNINECASN--PCLNQGTCIDDV 810
Query: 279 GSCE-SCEPGWNGTQCQ---QPCLPGTF--GESCEQQ---------CPHCRHGEACEPDT 323
+ +C + G C+ PC P G C Q CP G+ CE D
Sbjct: 811 AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDI 870
Query: 324 GHC 326
C
Sbjct: 871 NEC 873
Score = 96.3 bits (238), Expect = 9e-20
Identities = 91/329 (27%), Positives = 118/329 (35%), Gaps = 93/329 (28%)
Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF- 131
C C PG+ G +C +C ES PC G C+ T C C+ G C+
Sbjct: 739 CDCDPGWSGTNCDIN------NNEC-ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTN 791
Query: 132 --PCACGP---HGRC--DPATGVCHCEPGWWSSTCR------RPCQCNTAAARCEQATG- 177
CA P G C D A C+C + +TC P C C Q+
Sbjct: 792 INECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGG-ECRQSEDY 850
Query: 178 ---ACVCKPGWWGRRCSFRCN------C-HGSPCEQDSG--RCACRPGWWGPECQQQCEC 225
+CVC GW G+ C N C HG+ C+ G RC C+ G+ G C+ +
Sbjct: 851 ESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDD 910
Query: 226 VRGRCSAASGECT---------CPPGFRGARCE-------------------------LP 251
R G CT C PGFRG CE
Sbjct: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
Query: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES--------CEPGWNGTQCQ--------Q 295
CPAG G+ C ++ C E + G+C C PG+ G+ CQ Q
Sbjct: 971 CPAGFSGIHCENNTPDC--TESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQ 1028
Query: 296 PCL-PGTFGESCEQ---QCPHCRHGEACE 320
PCL GT + C CP G C+
Sbjct: 1029 PCLHGGTCQDGCGSYRCTCPQGYTGPNCQ 1057
Score = 89.4 bits (220), Expect = 1e-17
Identities = 102/374 (27%), Positives = 134/374 (35%), Gaps = 70/374 (18%)
Query: 18 QGSELDPKGQH--VCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVK---P 72
QG ++ QH +CV + + +C AG+ E + C P CQ C
Sbjct: 1108 QGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECS-PSPCQNGATCTDYLGG 1166
Query: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCE--PATGACQCQADRWGARCE 130
C+C G+ G +CS +C S PC G C P T C C G CE
Sbjct: 1167 YSCKCVAGYHGVNCSEEID------ECL-SHPCQNGGTCLDLPNTYKCSCPRGTQGVHCE 1219
Query: 131 FPCA-CGP-------------HGRCDPATG--VCHCEPGWWSSTCR---RPCQCNTAAAR 171
C P +G C G C C PG+ C C N AR
Sbjct: 1220 INVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDAR 1279
Query: 172 ----CEQATGA--CVCKPGWWGRRCSFRCN-CHGSPCEQDSGRCA------------CRP 212
C Q C C+ G GRRC N C G PC+ + G CA C
Sbjct: 1280 GTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK-NGGTCAVASNTARGFICKCPA 1338
Query: 213 GWWGPECQQQ---CECVR----GRCSAA--SGECTCPPGFRGARCELPCPAGSHGVQCAH 263
G+ G C+ C +R G C + S C C F G C+ P + G +
Sbjct: 1339 GFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCY 1398
Query: 264 SCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDT 323
+ G C EP S C +NG C L +FG + P EACE
Sbjct: 1399 NQGTC---EPTSESPFYRCLCPAKFNGLLCH--ILDYSFGGGAGRDIPPPLIEEACE--L 1451
Query: 324 GHCQRCSGSRDTAL 337
CQ +G++ +L
Sbjct: 1452 PECQEDAGNKVCSL 1465
Score = 89.0 bits (219), Expect = 1e-17
Identities = 91/345 (26%), Positives = 119/345 (34%), Gaps = 65/345 (18%)
Query: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
+C GW K C+ D C + C G +C P F A CP + GP C
Sbjct: 128 RCPPGWSGKS-------CQQADPCASNP-CANGG--QCLP--FEASYICHCPPSFHGPTC 175
Query: 100 RESCP--------CHPHGQCEPATGA--CQCQADRWGARCE---FPCA---CGPHGRCDP 143
R+ C G C G+ C C+A G CE PC+ C G C P
Sbjct: 176 RQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRP 235
Query: 144 ATGVCH---CEPGWWSSTCRRPCQCNTAAARCEQATGACV---------CKPGWWGRRCS 191
V H C PG+ C + C+ GACV C P W G+ C+
Sbjct: 236 TGDVTHECACLPGFTGQNCEENID-DCPGNNCKNG-GACVDGVNTYNCRCPPEWTGQYCT 293
Query: 192 F---RCNC------HGSPCEQDSG--RCACRPGWWGPECQQQCE-CVRGRCSAASGECTC 239
C +G C G C C GW G +C + + C C + TC
Sbjct: 294 EDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA---TC 350
Query: 240 PPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLP 299
CE CP G G+ C H C N PC+ + +C+ + C
Sbjct: 351 HDRVASFYCE--CPHGRTGLLC-HLNDACISN-PCNEGS----NCDTNPVNGKAICTCPS 402
Query: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVP 344
G G +C Q C G G C GS + + G P
Sbjct: 403 GYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGP 447
Score = 88.6 bits (218), Expect = 2e-17
Identities = 79/306 (25%), Positives = 108/306 (35%), Gaps = 51/306 (16%)
Query: 55 PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR----ESC---PCHP 107
P C+ P+ C C G C A + C + GP C +C PC
Sbjct: 55 PRCQDPNPCLSTP-CKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRN 113
Query: 108 HGQCEPATGA---CQCQADRWGARCEF--PCA---CGPHGRCDP--ATGVCHCEPGWWSS 157
G C+ T C+C G C+ PCA C G+C P A+ +CHC P +
Sbjct: 114 GGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGP 173
Query: 158 TCRRPC-QCNTAAARC--------EQATGACVCKPGWWGRRCSFR-CNCHGSPCEQD--- 204
TCR+ +C C E + CVC+ G C C SPC+
Sbjct: 174 TCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTC 233
Query: 205 ------SGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHG 258
+ CAC PG+ G C++ + G G C G C CP G
Sbjct: 234 RPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACV--DGVNTYNCR--CPPEWTG 289
Query: 259 VQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR---- 314
C C+ + G+C + G+N C+ G GE C + C
Sbjct: 290 QYCTEDVDECQLMPNACQNGGTCHNTHGGYNCV-----CVNGWTGEDCSENIDDCASAAC 344
Query: 315 -HGEAC 319
HG C
Sbjct: 345 FHGATC 350
Score = 88.2 bits (217), Expect = 3e-17
Identities = 97/391 (24%), Positives = 122/391 (31%), Gaps = 119/391 (30%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVC---VKPGLCRCKPGFFGAHCSSRCPGQYWGP 97
C AG+ ++ E I C P+ C C + C C PGF G C
Sbjct: 895 CQAGYSGRNCETDIDDCR-PNPCHNGGSCTDGINTAFCDCLPGFRGTFCEE--------- 944
Query: 98 DCRE--SCPCHPHGQCEPATGA--CQCQADRWGARCE------FPCACGPHGRCDPATG- 146
D E S PC C + C C A G CE +C G C
Sbjct: 945 DINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINS 1004
Query: 147 -VCHCEPGWWSSTCRRPC-QCNTA----AARCEQATGA--CVCKPGWWGRRCSFRCN-CH 197
C C PG+ S C+ +C++ C+ G+ C C G+ G C + C
Sbjct: 1005 FTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCD 1064
Query: 198 GSPCEQDSG--------RCACRPGWWGPEC---QQQCE-------------CVRGRCSAA 233
SPC+ RC C GW G C CE C G
Sbjct: 1065 SSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVD 1124
Query: 234 SG---ECTCPPGFRGARCE-------------------------LPCPAGSHGVQCAHSC 265
+G C C G+ G+ CE C AG HGV C+
Sbjct: 1125 AGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI 1184
Query: 266 GRCKHNEPCS--------PDTGSCESCEPGWNGTQCQ----------------------Q 295
C + PC P+T C SC G G C+
Sbjct: 1185 DECL-SHPCQNGGTCLDLPNTYKC-SCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNG 1242
Query: 296 PCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
C+ G SC CP GE CE D C
Sbjct: 1243 TCVDQVGGYSC--TCPPGFVGERCEGDVNEC 1271
Score = 87.8 bits (216), Expect = 3e-17
Identities = 96/369 (26%), Positives = 117/369 (31%), Gaps = 97/369 (26%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDA-----CQKD--EVCVKPGLCRCKPGFF 82
C + P A C G + E + IC P + C++D E KPGLCR
Sbjct: 138 CQQADPCASNPCANGGQCLPFEASY-ICHCPPSFHGPTCRQDVNECGQKPGLCR-----H 191
Query: 83 GAHCSSR-------CPGQYWGPDC-RESCPCHPH-----GQCEPA---TGACQCQADRWG 126
G C + C + GP+C R PC P G C P T C C G
Sbjct: 192 GGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTG 251
Query: 127 ARCEFPCACGPHGRCDPA--------TGVCHCEPGWWSSTCRRP---CQCNTAAAR---- 171
CE P C T C C P W C CQ A +
Sbjct: 252 QNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGT 311
Query: 172 CEQATGA--CVCKPGWWGRRCSFRCN-------CHGSPCEQD--SGRCACRPGWWGPECQ 220
C G CVC GW G CS + HG+ C S C C G G C
Sbjct: 312 CHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCH 371
Query: 221 QQCECVRGRCSAASG----------ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKH 270
C+ C+ S CTCP G+ G C +C+ C+H
Sbjct: 372 LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVD------ECSLGANPCEH 425
Query: 271 NEPCSPDTGSCE-SCEPGWNGTQC-------------------------QQPCLPGTFGE 304
C GS E C G+ G +C Q C+PG G
Sbjct: 426 AGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGV 485
Query: 305 SCEQQCPHC 313
CE C
Sbjct: 486 HCEVNTDEC 494
Score = 85.9 bits (211), Expect = 1e-16
Identities = 105/425 (24%), Positives = 136/425 (32%), Gaps = 101/425 (23%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCV---KPGLCRCKPGFFGAHC 86
C S C AG+ E P C +C CV C C PGF G++C
Sbjct: 960 CTDCVDSYTCTCPAGFSGIHCENNTPDCT-ESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 87 SS-------------------------RCPGQYWGPDCR------ESCPCHPHGQC--EP 113
CP Y GP+C+ +S PC G+C
Sbjct: 1019 QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
Query: 114 ATGACQCQADRWGARCEFPCA----------------CGPHGRCDPA--TGVCHCEPGWW 155
C+C + G C+ P C G C A T C C+ G+
Sbjct: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Query: 156 SSTCR------RPCQCNTAAARCEQATG-ACVCKPGWWGRRCSFRCN-CHGSPCEQ---- 203
S C P C A + G +C C G+ G CS + C PC+
Sbjct: 1139 GSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC 1198
Query: 204 ----DSGRCACRPGWWGPECQ--------------QQCECVR-GRCSAASG--ECTCPPG 242
++ +C+C G G C+ + +C G C G CTCPPG
Sbjct: 1199 LDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPG 1258
Query: 243 FRGARCE------LPCPAGSHGVQCAHSCGRCKHNEPCSPDTG-SCESCEPGWNGTQCQQ 295
F G RCE L P + G Q H E + TG CES G G C+
Sbjct: 1259 FVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKN 1318
Query: 296 P---CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLL---F 349
+ +CP G CE D C I+G P L F
Sbjct: 1319 GGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPF 1378
Query: 350 LGLAC 354
G C
Sbjct: 1379 TGPEC 1383
Score = 62.4 bits (150), Expect = 1e-09
Identities = 55/195 (28%), Positives = 69/195 (35%), Gaps = 53/195 (27%)
Query: 159 CRRPCQCNTAAARCEQATG--ACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWG 216
C +P + +CE A G ACVC + G RC C +PC+ ++G C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCK-NAGTCH------- 75
Query: 217 PECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSP 276
V R A C+C GF G C P C N PC
Sbjct: 76 ---------VVDRRGVADYACSCALGFSGPLCLTPLD------------NACLTN-PCR- 112
Query: 277 DTGSCE---------SCEPGWNGTQCQQ-------PCLPG----TFGESCEQQCPHCRHG 316
+ G+C+ C PGW+G CQQ PC G F S CP HG
Sbjct: 113 NGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHG 172
Query: 317 EACEPDTGHCQRCSG 331
C D C + G
Sbjct: 173 PTCRQDVNECGQKPG 187
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 112 bits (280), Expect = 1e-24
Identities = 83/287 (28%), Positives = 114/287 (39%), Gaps = 55/287 (19%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQY-WGPDCRESCPCHPHGQ----CEPATGACQCQADRWGA 127
G C+C+P G C+ PG + +GP + C CH G C P TG C C +
Sbjct: 790 GQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYAR 849
Query: 128 RCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV-CKPGWW 186
+C+ C PG W +PCQCN A C+ TG C+ C+
Sbjct: 850 QCD------------------RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTM 891
Query: 187 GRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQC--ECVRGRCSAASGECTCPPG 242
G C RC +G P C P GP+ +Q C + + C C PG
Sbjct: 892 GHNCE-RCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLA-CVCDPG 949
Query: 243 FRGARCELPCPAGSHG--VQCAHSCGRCK-HN-------EPCSPDTGSCESCEPGWNGTQ 292
+ G+RC+ C +G G + SC C+ HN E C +TG C C G
Sbjct: 950 YIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEH 1008
Query: 293 CQQPCLPGTFGESCEQQC------------PHCRHGEA-CEPDTGHC 326
CQ C G +G++ +Q C HC + C+ TG C
Sbjct: 1009 CQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC 1054
Score = 103 bits (256), Expect = 8e-22
Identities = 101/388 (26%), Positives = 142/388 (36%), Gaps = 89/388 (22%)
Query: 21 ELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIP--ICEGPDACQKDEVCVK------- 71
E DP+G V + QC + P GP C+ E ++
Sbjct: 774 ECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFC 833
Query: 72 ---PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG-QCEPATGAC-QCQADRWG 126
G C C G + C PG + P C + C C+ H C+P TG C CQ G
Sbjct: 834 NPVTGQCHCFQGVYARQCDRCLPGHWGFPSC-QPCQCNGHADDCDPVTGECLNCQDYTMG 892
Query: 127 ARCE--------------------FPCACGP-HGR-----C--DPAT--GVCHCEPGWWS 156
CE PC GP GR C DP T C C+PG+
Sbjct: 893 HNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIG 952
Query: 157 STCR-----------------RPCQCN-----TAAARCEQATGACV-CKPGWWGRRCSF- 192
S C +PCQC+ T C++ TG C+ C G C F
Sbjct: 953 SRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFC 1012
Query: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPC 252
R +G +QD +C C + Q+ C +C A+G+C C P G C+ C
Sbjct: 1013 RFGYYGDALQQDCRKCVCN---YLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCD-RC 1068
Query: 253 PAGSHGVQCAHSCGRCKHN------EPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESC 306
+ + C C N C+ TG C+ C PG+ G C + C +G+
Sbjct: 1069 APNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQ-CMPGFGGRTCSE-CQELFWGDP- 1125
Query: 307 EQQCPHCRHGEACEP---DTGHCQRCSG 331
+ +C C C+P +T C + +G
Sbjct: 1126 DVECRAC----DCDPRGIETPQCDQSTG 1149
Score = 93.2 bits (230), Expect = 8e-19
Identities = 81/295 (27%), Positives = 116/295 (39%), Gaps = 85/295 (28%)
Query: 55 PICEGPDA-------CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP-DCRESC-PC 105
P +GPD+ C +D V ++ C C PG+ G+ C G + P + SC PC
Sbjct: 918 PCPDGPDSGRQFARSCYQDPVTLQLA-CVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Query: 106 HPHGQ--------CEPATGAC-QCQADRWGARCEFPCACGPHGRC---DPATGVCHCEPG 153
H C+ TG C +C G C+F C G +G D VC+
Sbjct: 977 QCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQDCRKCVCN---- 1031
Query: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF---------------RCNCH- 197
+ T + CN + +C++ATG C+C P G+ C CNC+
Sbjct: 1032 -YLGTVQE--HCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNA 1088
Query: 198 ----GSPCEQDSGRCACRPGWWG---PECQQ-----------QCEC-VRG----RCSAAS 234
G C + +G+C C PG+ G ECQ+ C+C RG +C ++
Sbjct: 1089 AHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQST 1148
Query: 235 GECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWN 289
G+C C G G RC+ C G GV PD C C W+
Sbjct: 1149 GQCVCVEGVEGPRCD-KCTRGYSGV---------------FPDCTPCHQCFALWD 1187
Score = 58.5 bits (140), Expect = 2e-08
Identities = 44/141 (31%), Positives = 55/141 (39%), Gaps = 32/141 (22%)
Query: 194 CNCH-----GSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
C C S C+ + G+C CRP G C + C PG G
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-----------------CAPGTFGFG- 814
Query: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
P+G +C H G N C+P TG C C G QC + CLPG +G Q
Sbjct: 815 ----PSGCKPCEC-HLQGSV--NAFCNPVTGQCH-CFQGVYARQCDR-CLPGHWGFPSCQ 865
Query: 309 QCPHCRHGEACEPDTGHCQRC 329
C H + C+P TG C C
Sbjct: 866 PCQCNGHADDCDPVTGECLNC 886
Score = 50.4 bits (119), Expect = 6e-06
Identities = 50/221 (22%), Positives = 73/221 (33%), Gaps = 79/221 (35%)
Query: 70 VKPGLCR-CKPGFFGAHCSSRCPGQYWGP--DCR-----ESCPCHPHGQ-----CEPAT- 115
V G+C C+ G +C P Y P D R E C C P G C+ T
Sbjct: 357 VSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTD 416
Query: 116 -------GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA 168
G C+C+ + G C+ C+ G++ + P C +
Sbjct: 417 FSTGLIAGQCRCKLNVEGEHCDV------------------CKEGFYDLSSEDPFGCKS- 457
Query: 169 AARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQ------- 221
C C P G+PC+ ++G C C+ G C Q
Sbjct: 458 ----------CACNP--------LGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWG 499
Query: 222 ---------QCEC-----VRGRCSAASGECTCPPGFRGARC 248
C+C + C A SG+C+C P G +C
Sbjct: 500 LSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Score = 40.0 bits (92), Expect = 0.008
Identities = 62/263 (23%), Positives = 85/263 (32%), Gaps = 87/263 (33%)
Query: 100 RESCPCHPHG-QCEPATGA-----------CQCQADRWGARCEFPCACGPH--------G 139
R +C C+ H +C P G C C+ + G CE C H G
Sbjct: 268 RGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCEL-CMDFYHDLPWRPAEG 326
Query: 140 RCDPATGVCHCEP---------------GWWSSTCRRPCQCNTAAARCEQATGACVCKPG 184
R A C+C G S CQ NT CEQ CKP
Sbjct: 327 RNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQ------CKPF 380
Query: 185 WWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAA-SGECTCPPGF 243
++ R + CE RC C P G + + C+ + +G+C C
Sbjct: 381 YYQH--PERDIRDPNFCE----RCTCDPA--GSQNEGICDSYTDFSTGLIAGQCRCKLNV 432
Query: 244 RGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFG 303
G C++ C G + + S D C+SC GT +PG
Sbjct: 433 EGEHCDV-CKEGFYDLS--------------SEDPFGCKSCACNPLGT------IPG--- 468
Query: 304 ESCEQQCPHCRHGEACEPDTGHC 326
G C+ +TGHC
Sbjct: 469 ------------GNPCDSETGHC 479
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 110 bits (276), Expect = 4e-24
Identities = 90/297 (30%), Positives = 113/297 (38%), Gaps = 79/297 (26%)
Query: 56 ICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
IC+ P C K CV P +C+CKPG+ G++C + PDC+ HG+C
Sbjct: 1297 ICKYP--CGKSRECVAPNICKCKPGYIGSNCQT----ALCDPDCKN------HGKC-IKP 1343
Query: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA 175
CQC GA C+ HC P PCQ A
Sbjct: 1344 NICQCLPGHGGATCDEE----------------HCNP---------PCQHGGTCL----A 1374
Query: 176 TGACVCKPGWWGRRC-SFRCNCH---GSPCEQDSGRCACRPGWWGPECQQQ-CE--CVRG 228
C C G+ G RC + CN H G C C C+PGW+GP C C+ C+ G
Sbjct: 1375 GNLCTCPYGFVGPRCETMVCNRHCENGGQC-LTPDICQCKPGWYGPTCSTALCDPVCLNG 1433
Query: 229 RCSAASGECTCPPGFRG-----ARCELPCPAGSHGVQ-----CAHS-CGRCKHNEPCSP- 276
C CP GF G A C PC G H ++ C GR C P
Sbjct: 1434 GSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPT 1493
Query: 277 --DTGSCE-----SCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
+ G C SC GW+G +C P C Q+C + GE P HC
Sbjct: 1494 CMNGGKCVGPSTCSCPSGWSGKRCNTPI--------CLQKCKN--GGECIAPSICHC 1540
Score = 64.3 bits (155), Expect = 4e-10
Identities = 57/205 (27%), Positives = 77/205 (37%), Gaps = 43/205 (20%)
Query: 40 QCCAGWRQKDQECTI--PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP 97
QC GW + P+C +C KP C C GFFG HC + + P
Sbjct: 1411 QCKPGWYGPTCSTALCDPVCLNGGSCN------KPNTCLCPNGFFGEHCQN----AFCHP 1460
Query: 98 DCRESCPCHPHGQCEPATGACQCQADRWGAR-----CEFPCACGPHGRC-DPATGVCHCE 151
PC G C C C+ G R C+ C G G+C P+T C C
Sbjct: 1461 ------PCKNGGHC-MRNNVCVCREGYTGRRFQKSICDPTCMNG--GKCVGPST--CSCP 1509
Query: 152 PGWWSSTCRRPCQCNTAAARCEQ-----ATGACVCKPGWWGRRCSFR-CN---CHGSPCE 202
GW C P +C+ A C C W G RC CN +G C
Sbjct: 1510 SGWSGKRCNTP----ICLQKCKNGGECIAPSICHCPSSWEGVRCQIPICNPKCLYGGRCI 1565
Query: 203 QDSGRCACRPGWWGPECQQQCECVR 227
+ C+CR + G +C+++ + R
Sbjct: 1566 FPN-VCSCRTEYSGVKCEKKIQIRR 1589
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/185 (24%), Positives = 65/185 (35%), Gaps = 60/185 (32%)
Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPEC----QQQCEC--------- 225
CVC PG+ HGS CE D C P G C+C
Sbjct: 1204 CVCLPGF-----------HGSLCEVDISGCQSNPCGLGSYISGFHSYSCDCPPELKVETQ 1252
Query: 226 ----------VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCS 275
V R + + +G + + +G+ C + CG K E +
Sbjct: 1253 FVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCG--KSRECVA 1310
Query: 276 PDTGSCESCEPGWNGTQCQQ-------------------PCLPGTFGESC-EQQC-PHCR 314
P+ C+ C+PG+ G+ CQ CLPG G +C E+ C P C+
Sbjct: 1311 PNI--CK-CKPGYIGSNCQTALCDPDCKNHGKCIKPNICQCLPGHGGATCDEEHCNPPCQ 1367
Query: 315 HGEAC 319
HG C
Sbjct: 1368 HGGTC 1372
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 110 bits (275), Expect = 5e-24
Identities = 106/405 (26%), Positives = 142/405 (35%), Gaps = 126/405 (31%)
Query: 74 LCRCKPGFFGAHCSS------RCPGQYWGPDCRESCPCHPHGQ-CEPATGAC-QCQADRW 125
+C+C PG+ G+ C S R G +G C E C C H + C+ TG C C+
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 126 GARCE------------------FPCACGPHGRCDPATGVCH-----------CEPGWWS 156
G C+ PCAC + + + CH C G+
Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTG 841
Query: 157 STCRR-----------------PCQCN-----TAAARCEQATGAC-VCKPGWWGRRCSF- 192
C R PCQCN + C+ +G+C +CKPG GR C
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 193 -----------------RCNCHGS---PCEQDSGRCACRPGWWGPEC----------QQQ 222
RCN GS C +G+C CR G C Q
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961
Query: 223 CECVRGRCSA---------ASGECTCPPGFRGARCELPCPAGSHGVQ----CAHSCGRCK 269
CV C++ SG+C C PG G +C+ C G Q A C
Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTACECSHLG 1020
Query: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA------CEPDT 323
+N C P TG C C P G +C + C P T+G S C C C +T
Sbjct: 1021 NN--CDPKTGRC-ICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNT 1076
Query: 324 GHCQ---RCSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSD 365
G C + SG++ T G + C C C+ P +D
Sbjct: 1077 GQCNCHPKFSGAKCTECSRGH-------WNYPRCNLCDCFLPGTD 1114
Score = 99.8 bits (247), Expect = 8e-21
Identities = 83/325 (25%), Positives = 113/325 (34%), Gaps = 103/325 (31%)
Query: 77 CKPGFFGAHCSSRCPGQYWGP-----DCRESCPCHPHGQ----CEPATGACQCQADRWGA 127
CKPG G +C C Y+G +C + C C+ G C TG C+C+A+ G
Sbjct: 889 CKPGTTGRYCEL-CADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQ 946
Query: 128 RCE---------------FPCACGPHGR----CDPATGVCHCEPGWWSSTCRR------- 161
RC+ PC C G C+ + G C C+PG C R
Sbjct: 947 RCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEES-GQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 162 -------PCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGW 214
C+C+ C+ TG C+C P G +CS C P
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCS-----------------KCAPNT 1048
Query: 215 WGPECQQQCEC--------VRGRCSAASGECTCPPGFRGARCE----------------- 249
WG C+ + +C+ +G+C C P F GA+C
Sbjct: 1049 WGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDC 1108
Query: 250 -LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
LP G+ C +C CS TG C +C+ G C + C PG FG +
Sbjct: 1109 FLP---GTDATTCDSETKKCS----CSDQTGQC-TCKVNVEGIHCDR-CRPGKFGLDAKN 1159
Query: 309 Q--CPHCRHGEACEPDTGHCQRCSG 331
C C C T C G
Sbjct: 1160 PLGCSSC----YCFGTTTQCSEAKG 1180
Score = 81.6 bits (200), Expect = 2e-15
Identities = 85/330 (25%), Positives = 115/330 (34%), Gaps = 109/330 (33%)
Query: 101 ESCPCHP-HGQCEPATGACQCQADRWGARCEF------------------PCACGPHGR- 140
ES +P G A CQC G+ CE PC C H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAES 765
Query: 141 CDPATGVC-------------HCEPGWWSSTCR------RPCQC------NTAAARC--E 173
CD TG C C PG++ + +PC C N + C +
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD 825
Query: 174 QATGACV--CKPGWWGRRCS-----------------FRCNCHGS-------PCEQDSGR 207
++ G C G+ G RC C C+ + C+ SG
Sbjct: 826 RSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS 885
Query: 208 C-ACRPGWWGPECQ----------------QQCECVRGR-----CSAASGECTCPPGFRG 245
C C+PG G C+ Q C C G C + +G+C C +G
Sbjct: 886 CLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQG 945
Query: 246 ARCELPCPAGSHGVQCAHSCGRCKHNEPCS-----PDTGSCESCEPGWNGTQCQQPCLPG 300
RC+ C AG+ G+Q A C C N S ++G C C+PG G +C + C G
Sbjct: 946 QRCD-KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDR-CAHG 1002
Query: 301 TF----GESCEQQCPHCRHGEACEPDTGHC 326
F G +C H G C+P TG C
Sbjct: 1003 YFNFQEGGCTACECSHL--GNNCDPKTGRC 1030
Score = 75.9 bits (185), Expect = 1e-13
Identities = 64/238 (26%), Positives = 87/238 (36%), Gaps = 50/238 (21%)
Query: 69 CVKPGLCRCKPGFFGAHCSSRCPGQYWG---PDCRESCPC-HPHGQCEPATGACQCQADR 124
C + G C C+PG G C RC Y+ C +C C H C+P TG C C +
Sbjct: 979 CEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECSHLGNNCDPKTGRCICPPNT 1036
Query: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWS---STCRRPCQCNTAAA---RCEQATGA 178
G +C C P W +T + C C+T + +C TG
Sbjct: 1037 IGEKCS------------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078
Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC-RPGWWGPECQQQCECVRGRCSAASGEC 237
C C P + G +C+ C+ G C C PG C E + CS +G+C
Sbjct: 1079 CNCHPKFSGAKCT-ECS-RGHWNYPRCNLCDCFLPGTDATTCDS--ETKKCSCSDQTGQC 1134
Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
TC G C+ C G G+ + G C SC TQC +
Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLG--------------CSSCYCFGTTTQCSE 1177
Score = 57.8 bits (138), Expect = 4e-08
Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 38/196 (19%)
Query: 75 CRCKPGFFGAHCSSRCPGQYW----------GPDCRESCPCHPHGQ---CEPATGACQ-C 120
C C G+ G C + PG Y GP PC +G C+P T CQ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
Q G CE CA G +G C + C C ++ + +CV
Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC------------QQCACPLISSS-NNFSPSCV 1485
Query: 181 CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAA 233
+ G RC+ C G CE+ + PG G CQ+ CEC + C
Sbjct: 1486 AE-GLDDYRCT-ACPRGYEGQYCERCAPGYTGSPGNPGGSCQE-CECDPYGSLPVPCDPV 1542
Query: 234 SGECTCPPGFRGARCE 249
+G CTC PG G +C+
Sbjct: 1543 TGFCTCRPGATGRKCD 1558
Score = 54.7 bits (130), Expect = 3e-07
Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGS--HGVQCAHSCGRCK---HNEPCSPDTGSCE 282
G +AA C CPPG+ G+ CE P +G C C+ H E C TG C
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL 774
Query: 283 SCEPGWNGTQCQQPCLPGTFGE---SCEQQCPHCRHGEACE---PDTGHCQRCSGSRDTA 336
+C+ G C + CLPG +GE + C C AC P C R
Sbjct: 775 NCKDHTGGPYCDK-CLPGFYGEPTKGTSEDCQPC----ACPLNIPSNNFSPTCHLDRSLG 829
Query: 337 LI 338
LI
Sbjct: 830 LI 831
Score = 51.2 bits (121), Expect = 3e-06
Identities = 59/223 (26%), Positives = 79/223 (35%), Gaps = 41/223 (18%)
Query: 40 QCCAGWRQKD---------QECTIPICEGP-DACQKDEVCVKPGLC-RCKPGFFGAHCSS 88
QCC G+ QK EC C G + C DE + L + + G
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379
Query: 89 RCPGQYWGPDCRESCP---CHPHGQCEPATGACQ-CQADRWGARCEFPCACGPHGRCDPA 144
C G +C E+C P G CQ C D G+ E H R A
Sbjct: 380 NCTQNTAGINC-ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLA 438
Query: 145 TGVCHCEPGWWSSTCRR------------PCQCNTAAARCEQ-ATGACVCKPGWWGRRCS 191
G CHC+ G+ +C R C C+ ++ E G C+CK G CS
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498
Query: 192 FRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCECVRGRCSAA 233
RC ++D+ W G EC C V RC ++
Sbjct: 499 -RCKSGFFNLQEDN--------WKGCDEC--FCSGVSNRCQSS 530
Score = 50.1 bits (118), Expect = 8e-06
Identities = 61/221 (27%), Positives = 74/221 (33%), Gaps = 66/221 (29%)
Query: 118 CQCQADRWGARCEFPCACGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ 174
C C G CE AC P R P PG TC PCQCN ++ C+
Sbjct: 1380 CDCPLGYSGLSCE---ACLPGFYRLRSQPGGRT----PGPTLGTCV-PCQCNGHSSLCDP 1431
Query: 175 ATGACVCKPGWWGRRCSFRCNCH--GSPCEQDSGRCACRPGWWG-----PECQQQCECVR 227
T C C H G CE+ C G++G P QQC C
Sbjct: 1432 ETSICQ------------NCQHHTAGDFCER------CALGYYGIVKGLPNDCQQCACPL 1473
Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287
S G RC CP G G C E C PG
Sbjct: 1474 ISSSNNFSPSCVAEGLDDYRCTA-CPRGYEGQYC--------------------ERCAPG 1512
Query: 288 WNGTQCQQPCLPGTFGESCEQ-QC-PHCRHGEACEPDTGHC 326
+ G+ PG G SC++ +C P+ C+P TG C
Sbjct: 1513 YTGS-------PGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Score = 46.6 bits (109), Expect = 8e-05
Identities = 58/224 (25%), Positives = 74/224 (33%), Gaps = 70/224 (31%)
Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP----------DCRESCP 104
IC G AC D K C C+ G C CPG + P +C E+C
Sbjct: 288 ICYGHARACPLDPATNK-SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACN 345
Query: 105 CHPHGQCEP---------------------ATGAC-QCQADRWGARCEFPCACG---PHG 139
C HG+ E G C C + G CE C G P G
Sbjct: 346 C--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPKG 402
Query: 140 -------RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS- 191
C P CHC+P + C + AR A G+C CK G+ G C
Sbjct: 403 VSPNYPRPCQP----CHCDP---IGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455
Query: 192 -----------FRCNCHGSPCEQDS---GRCACRPGWWGPECQQ 221
CNC G + + G C C+ G +C +
Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 46.2 bits (108), Expect = 1e-04
Identities = 49/179 (27%), Positives = 65/179 (36%), Gaps = 38/179 (21%)
Query: 19 GSELDPK-GQHVCVASSPSAELQCCAG--WRQKDQECTIPICEGPDACQKDEV------C 69
G+ DPK G+ +C ++ + CA W I G AC V C
Sbjct: 1020 GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-------ITTGCKACNCSTVGSLDFQC 1072
Query: 70 -VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADR 124
V G C C P F GA C+ G + P C C C G C+ T C C +D+
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC-SDQ 1130
Query: 125 WGARCEFPCACGPHG-RCDPATGVCHCEPGWWSSTCRRP-----CQCNTAAARCEQATG 177
G + C G CD C PG + + P C C +C +A G
Sbjct: 1131 TG---QCTCKVNVEGIHCD------RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 15/92 (16%)
Query: 236 ECTCPPGFRGARCE--LPC-------PAGSHGVQCAHSCGRCK---HNEPCSPDTGSCES 283
+C CP G+ G CE LP P G +C C+ H+ C P+T C++
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 284 CEPGWNGTQCQQPCLPGTFG--ESCEQQCPHC 313
C+ G C++ C G +G + C C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQC 1469
Score = 33.1 bits (74), Expect = 0.96
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 280 SCESCEPGWNGTQCQQPC-LPG-TFGESCEQQCPHCRHGEACEPDTGHCQRC 329
SCE+C PG+ + Q PG T G QC H C+P+T CQ C
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG--HSSLCDPETSICQNC 1439
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 110 bits (275), Expect = 5e-24
Identities = 106/405 (26%), Positives = 142/405 (35%), Gaps = 126/405 (31%)
Query: 74 LCRCKPGFFGAHCSS------RCPGQYWGPDCRESCPCHPHGQ-CEPATGAC-QCQADRW 125
+C+C PG+ G+ C S R G +G C E C C H + C+ TG C C+
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTG 781
Query: 126 GARCE------------------FPCACGPHGRCDPATGVCH-----------CEPGWWS 156
G C+ PCAC + + + CH C G+
Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTG 841
Query: 157 STCRR-----------------PCQCN-----TAAARCEQATGAC-VCKPGWWGRRCSF- 192
C R PCQCN + C+ +G+C +CKPG GR C
Sbjct: 842 PRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELC 901
Query: 193 -----------------RCNCHGS---PCEQDSGRCACRPGWWGPEC----------QQQ 222
RCN GS C +G+C CR G C Q
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961
Query: 223 CECVRGRCSA---------ASGECTCPPGFRGARCELPCPAGSHGVQ----CAHSCGRCK 269
CV C++ SG+C C PG G +C+ C G Q A C
Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCTACECSHLG 1020
Query: 270 HNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEA------CEPDT 323
+N C P TG C C P G +C + C P T+G S C C C +T
Sbjct: 1021 NN--CDPKTGRC-ICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNT 1076
Query: 324 GHCQ---RCSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSD 365
G C + SG++ T G + C C C+ P +D
Sbjct: 1077 GQCNCHPKFSGAKCTECSRGH-------WNYPRCNLCDCFLPGTD 1114
Score = 99.8 bits (247), Expect = 8e-21
Identities = 83/325 (25%), Positives = 113/325 (34%), Gaps = 103/325 (31%)
Query: 77 CKPGFFGAHCSSRCPGQYWGP-----DCRESCPCHPHGQ----CEPATGACQCQADRWGA 127
CKPG G +C C Y+G +C + C C+ G C TG C+C+A+ G
Sbjct: 889 CKPGTTGRYCEL-CADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQ 946
Query: 128 RCE---------------FPCACGPHGR----CDPATGVCHCEPGWWSSTCRR------- 161
RC+ PC C G C+ + G C C+PG C R
Sbjct: 947 RCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEES-GQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 162 -------PCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGW 214
C+C+ C+ TG C+C P G +CS C P
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCS-----------------KCAPNT 1048
Query: 215 WGPECQQQCEC--------VRGRCSAASGECTCPPGFRGARCE----------------- 249
WG C+ + +C+ +G+C C P F GA+C
Sbjct: 1049 WGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPRCNLCDC 1108
Query: 250 -LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQ 308
LP G+ C +C CS TG C +C+ G C + C PG FG +
Sbjct: 1109 FLP---GTDATTCDSETKKCS----CSDQTGQC-TCKVNVEGIHCDR-CRPGKFGLDAKN 1159
Query: 309 Q--CPHCRHGEACEPDTGHCQRCSG 331
C C C T C G
Sbjct: 1160 PLGCSSC----YCFGTTTQCSEAKG 1180
Score = 81.6 bits (200), Expect = 2e-15
Identities = 85/330 (25%), Positives = 115/330 (34%), Gaps = 109/330 (33%)
Query: 101 ESCPCHP-HGQCEPATGACQCQADRWGARCEF------------------PCACGPHGR- 140
ES +P G A CQC G+ CE PC C H
Sbjct: 706 ESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAES 765
Query: 141 CDPATGVC-------------HCEPGWWSSTCR------RPCQC------NTAAARC--E 173
CD TG C C PG++ + +PC C N + C +
Sbjct: 766 CDDVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLD 825
Query: 174 QATGACV--CKPGWWGRRCS-----------------FRCNCHGS-------PCEQDSGR 207
++ G C G+ G RC C C+ + C+ SG
Sbjct: 826 RSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS 885
Query: 208 C-ACRPGWWGPECQ----------------QQCECVRGR-----CSAASGECTCPPGFRG 245
C C+PG G C+ Q C C G C + +G+C C +G
Sbjct: 886 CLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQG 945
Query: 246 ARCELPCPAGSHGVQCAHSCGRCKHNEPCS-----PDTGSCESCEPGWNGTQCQQPCLPG 300
RC+ C AG+ G+Q A C C N S ++G C C+PG G +C + C G
Sbjct: 946 QRCD-KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQC-WCQPGVTGKKCDR-CAHG 1002
Query: 301 TF----GESCEQQCPHCRHGEACEPDTGHC 326
F G +C H G C+P TG C
Sbjct: 1003 YFNFQEGGCTACECSHL--GNNCDPKTGRC 1030
Score = 75.9 bits (185), Expect = 1e-13
Identities = 64/238 (26%), Positives = 87/238 (36%), Gaps = 50/238 (21%)
Query: 69 CVKPGLCRCKPGFFGAHCSSRCPGQYWG---PDCRESCPC-HPHGQCEPATGACQCQADR 124
C + G C C+PG G C RC Y+ C +C C H C+P TG C C +
Sbjct: 979 CEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECSHLGNNCDPKTGRCICPPNT 1036
Query: 125 WGARCEFPCACGPHGRCDPATGVCHCEPGWWS---STCRRPCQCNTAAA---RCEQATGA 178
G +C C P W +T + C C+T + +C TG
Sbjct: 1037 IGEKCS------------------KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQ 1078
Query: 179 CVCKPGWWGRRCSFRCNCHGSPCEQDSGRCAC-RPGWWGPECQQQCECVRGRCSAASGEC 237
C C P + G +C+ C+ G C C PG C E + CS +G+C
Sbjct: 1079 CNCHPKFSGAKCT-ECS-RGHWNYPRCNLCDCFLPGTDATTCDS--ETKKCSCSDQTGQC 1134
Query: 238 TCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
TC G C+ C G G+ + G C SC TQC +
Sbjct: 1135 TCKVNVEGIHCD-RCRPGKFGLDAKNPLG--------------CSSCYCFGTTTQCSE 1177
Score = 57.8 bits (138), Expect = 4e-08
Identities = 56/196 (28%), Positives = 75/196 (38%), Gaps = 38/196 (19%)
Query: 75 CRCKPGFFGAHCSSRCPGQYW----------GPDCRESCPCHPHGQ---CEPATGACQ-C 120
C C G+ G C + PG Y GP PC +G C+P T CQ C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 121 QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACV 180
Q G CE CA G +G C + C C ++ + +CV
Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC------------QQCACPLISSS-NNFSPSCV 1485
Query: 181 CKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAA 233
+ G RC+ C G CE+ + PG G CQ+ CEC + C
Sbjct: 1486 AE-GLDDYRCT-ACPRGYEGQYCERCAPGYTGSPGNPGGSCQE-CECDPYGSLPVPCDPV 1542
Query: 234 SGECTCPPGFRGARCE 249
+G CTC PG G +C+
Sbjct: 1543 TGFCTCRPGATGRKCD 1558
Score = 54.7 bits (130), Expect = 3e-07
Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGS--HGVQCAHSCGRCK---HNEPCSPDTGSCE 282
G +AA C CPPG+ G+ CE P +G C C+ H E C TG C
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL 774
Query: 283 SCEPGWNGTQCQQPCLPGTFGE---SCEQQCPHCRHGEACE---PDTGHCQRCSGSRDTA 336
+C+ G C + CLPG +GE + C C AC P C R
Sbjct: 775 NCKDHTGGPYCDK-CLPGFYGEPTKGTSEDCQPC----ACPLNIPSNNFSPTCHLDRSLG 829
Query: 337 LI 338
LI
Sbjct: 830 LI 831
Score = 51.2 bits (121), Expect = 3e-06
Identities = 59/223 (26%), Positives = 79/223 (35%), Gaps = 41/223 (18%)
Query: 40 QCCAGWRQKD---------QECTIPICEGP-DACQKDEVCVKPGLC-RCKPGFFGAHCSS 88
QCC G+ QK EC C G + C DE + L + + G
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379
Query: 89 RCPGQYWGPDCRESCP---CHPHGQCEPATGACQ-CQADRWGARCEFPCACGPHGRCDPA 144
C G +C E+C P G CQ C D G+ E H R A
Sbjct: 380 NCTQNTAGINC-ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLA 438
Query: 145 TGVCHCEPGWWSSTCRR------------PCQCNTAAARCEQ-ATGACVCKPGWWGRRCS 191
G CHC+ G+ +C R C C+ ++ E G C+CK G CS
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498
Query: 192 FRCNCHGSPCEQDSGRCACRPGWWG-PECQQQCECVRGRCSAA 233
RC ++D+ W G EC C V RC ++
Sbjct: 499 -RCKSGFFNLQEDN--------WKGCDEC--FCSGVSNRCQSS 530
Score = 50.1 bits (118), Expect = 8e-06
Identities = 61/221 (27%), Positives = 74/221 (33%), Gaps = 66/221 (29%)
Query: 118 CQCQADRWGARCEFPCACGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ 174
C C G CE AC P R P PG TC PCQCN ++ C+
Sbjct: 1380 CDCPLGYSGLSCE---ACLPGFYRLRSQPGGRT----PGPTLGTCV-PCQCNGHSSLCDP 1431
Query: 175 ATGACVCKPGWWGRRCSFRCNCH--GSPCEQDSGRCACRPGWWG-----PECQQQCECVR 227
T C C H G CE+ C G++G P QQC C
Sbjct: 1432 ETSICQ------------NCQHHTAGDFCER------CALGYYGIVKGLPNDCQQCACPL 1473
Query: 228 GRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287
S G RC CP G G C E C PG
Sbjct: 1474 ISSSNNFSPSCVAEGLDDYRCTA-CPRGYEGQYC--------------------ERCAPG 1512
Query: 288 WNGTQCQQPCLPGTFGESCEQ-QC-PHCRHGEACEPDTGHC 326
+ G+ PG G SC++ +C P+ C+P TG C
Sbjct: 1513 YTGS-------PGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Score = 46.6 bits (109), Expect = 8e-05
Identities = 58/224 (25%), Positives = 74/224 (33%), Gaps = 70/224 (31%)
Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGP----------DCRESCP 104
IC G AC D K C C+ G C CPG + P +C E+C
Sbjct: 288 ICYGHARACPLDPATNK-SRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EACN 345
Query: 105 CHPHGQCEP---------------------ATGAC-QCQADRWGARCEFPCACG---PHG 139
C HG+ E G C C + G CE C G P G
Sbjct: 346 C--HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPKG 402
Query: 140 -------RCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS- 191
C P CHC+P + C + AR A G+C CK G+ G C
Sbjct: 403 VSPNYPRPCQP----CHCDP---IGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR 455
Query: 192 -----------FRCNCHGSPCEQDS---GRCACRPGWWGPECQQ 221
CNC G + + G C C+ G +C +
Sbjct: 456 CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 46.2 bits (108), Expect = 1e-04
Identities = 49/179 (27%), Positives = 65/179 (36%), Gaps = 38/179 (21%)
Query: 19 GSELDPK-GQHVCVASSPSAELQCCAG--WRQKDQECTIPICEGPDACQKDEV------C 69
G+ DPK G+ +C ++ + CA W I G AC V C
Sbjct: 1020 GNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHS-------ITTGCKACNCSTVGSLDFQC 1072
Query: 70 -VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHG----QCEPATGACQCQADR 124
V G C C P F GA C+ G + P C C C G C+ T C C +D+
Sbjct: 1073 NVNTGQCNCHPKFSGAKCTECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC-SDQ 1130
Query: 125 WGARCEFPCACGPHG-RCDPATGVCHCEPGWWSSTCRRP-----CQCNTAAARCEQATG 177
G + C G CD C PG + + P C C +C +A G
Sbjct: 1131 TG---QCTCKVNVEGIHCD------RCRPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKG 1180
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 15/92 (16%)
Query: 236 ECTCPPGFRGARCE--LPC-------PAGSHGVQCAHSCGRCK---HNEPCSPDTGSCES 283
+C CP G+ G CE LP P G +C C+ H+ C P+T C++
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 284 CEPGWNGTQCQQPCLPGTFG--ESCEQQCPHC 313
C+ G C++ C G +G + C C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQC 1469
Score = 33.1 bits (74), Expect = 0.96
Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 280 SCESCEPGWNGTQCQQPC-LPG-TFGESCEQQCPHCRHGEACEPDTGHCQRC 329
SCE+C PG+ + Q PG T G QC H C+P+T CQ C
Sbjct: 1390 SCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNG--HSSLCDPETSICQNC 1439
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 108 bits (270), Expect = 2e-23
Identities = 106/378 (28%), Positives = 134/378 (35%), Gaps = 80/378 (21%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPGLCRCKPGFFGAHCS 87
CV E +C G+ + + C PD C + C C PG+ G C
Sbjct: 522 CVDQPDGYECRCAEGFEGTLCDRNVDDCS-PDPCHHGRCVDGIASFSCACAPGYTGTRCE 580
Query: 88 SRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF---PCACGP--HGR 140
S+ +CR S PC G+C C+C + G CE CA P G
Sbjct: 581 SQVD------ECR-SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV 633
Query: 141 CDPATGV--CHCEPGWWSSTCR------RPCQCNTAAARCEQATG-ACVCKPGWWGRRC- 190
C C C+PG+ C C + + G C+C PG C
Sbjct: 634 CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCL 693
Query: 191 --SFRCN---CHGSPCEQDSG--RCACRPGWWGPECQQQ-----CE---CVRGRCSAASG 235
S C C C G RC C PGW GP C Q CE C G ++ G
Sbjct: 694 PPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG 753
Query: 236 ---ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQ 292
CTCPPG +G +CEL P + C H GRC+ +P SC GW G +
Sbjct: 754 MGFHCTCPPGVQGRQCELLSPCTPN--PCEHG-GRCE----SAPGQLPVCSCPQGWQGPR 806
Query: 293 CQQ---------PCLP-----------------GTFGESCEQQCPHCRHGEACEPDTGHC 326
CQQ PC P G G SC+Q C + G C
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL--NGGSC 864
Query: 327 QRCSGSRDTALIAGSLVP 344
Q GS + + G P
Sbjct: 865 QDGVGSFSCSCLPGFAGP 882
Score = 102 bits (255), Expect = 1e-21
Identities = 109/401 (27%), Positives = 129/401 (32%), Gaps = 120/401 (29%)
Query: 19 GSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCK 78
GS D G C A +C R D EC C GP C V C C
Sbjct: 862 GSCQDGVGSFSCSCLPGFAGPRCA---RDVD-ECLSNPC-GPGTCTDH---VASFTCTCP 913
Query: 79 PGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF---PC 133
PG+ G HC P DC S C G C + C C+ GA C+ PC
Sbjct: 914 PGYGGFHCEQDLP------DCSPSS-CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC 966
Query: 134 ACGP--HGRCDPATGVCHCEPGWWSSTC-----------------RRPCQCNTAAARCEQ 174
P HG GVC + TC R+PCQ RC Q
Sbjct: 967 LSRPCLHG------GVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ---NGGRCVQ 1017
Query: 175 ATGACVCKPGWWGRRCSFR------------------CNCHGSPCEQDSGR-CACRPGWW 215
C+C PGW GR C R C G ++DS C C G
Sbjct: 1018 TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT 1077
Query: 216 GPECQQQCE-CVR------GRCSAASG--ECTCPPGFRGARCE----------------- 249
G C+Q+ + C+ G C G C C PG+ G CE
Sbjct: 1078 GSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSC 1137
Query: 250 --------LPCPAGSHGVQC---AHSCG---------RCKHNEPCSPDTGSCE-SCEPGW 288
CP G+ GV C CG RC HN C G +C PG+
Sbjct: 1138 IDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY 1197
Query: 289 NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
G +C+ C H H C D G RC
Sbjct: 1198 TGLRCEADI------NECRSGACHAAHTRDCLQDPGGGFRC 1232
Score = 95.9 bits (237), Expect = 1e-19
Identities = 106/402 (26%), Positives = 132/402 (32%), Gaps = 90/402 (22%)
Query: 7 LPLLLLWTRGTQGSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPI------CEGP 60
LPLLLL G+ P C+ SP A C ++ C P C+
Sbjct: 27 LPLLLLLAG--PGAAAPP-----CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE 79
Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPC-------------HP 107
D C C G+C+ A S RCP + GPDC PC P
Sbjct: 80 DPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGP 138
Query: 108 HGQ----CEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPC 163
G+ C P C++D R PC G P + C C G+ C P
Sbjct: 139 DGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPA 198
Query: 164 -QCNTAAAR----CEQA---TGACVCKPGWWGRRCSFRC-NCHGSPCEQ--------DSG 206
C + R C Q+ T C C PG+ G+ C +C G C ++
Sbjct: 199 VPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258
Query: 207 RCACRPGWWG-------PECQQQ------------------CECVRG----RCSAASGEC 237
C C P W G ECQ Q C CV G CS +C
Sbjct: 259 NCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318
Query: 238 TCPPGFRGARCE-------LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNG 290
F GA C CP G G+ C H C N PC D C+
Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLC-HLDDACVSN-PCHEDA----ICDTNPVN 372
Query: 291 TQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGS 332
+ C PG G +C+Q C G G C GS
Sbjct: 373 GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGS 414
Score = 95.1 bits (235), Expect = 2e-19
Identities = 98/358 (27%), Positives = 111/358 (31%), Gaps = 98/358 (27%)
Query: 61 DACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESC------PCHPHGQCEPA 114
D C+ E C G C PG F +CP Y GP C PC G C +
Sbjct: 160 DECRVGEPCRHGGTCLNTPGSFRC----QCPAGYTGPLCENPAVPCAPSPCRNGGTCRQS 215
Query: 115 ---TGACQCQADRWGARCEFPCACGPHGRC--------DPATGVCHCEPGWWSSTCRRP- 162
T C C G CE P RC T C C P W C
Sbjct: 216 GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
Query: 163 --CQCNTAAAR----CEQATG--ACVCKPGWWGRRCSFRCN-------CHGSPCEQD--S 205
CQ A C G +CVC GW G CS + HG+ C S
Sbjct: 276 DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335
Query: 206 GRCACRPGWWGPECQQQCECVRGRC--------SAASGE--CTCPPGFRGARCELPCPAG 255
CAC G G C CV C + +G CTCPPGF G C+
Sbjct: 336 FYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDEC 395
Query: 256 SHGVQ-CAH-------------SCGRCKHNEPCSPDTGSCES------------------ 283
S G C H CGR C D C S
Sbjct: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
Query: 284 -CEPGWNGTQCQ--------QPCLPG------TFGESCEQQCPHCRHGEACEPDTGHC 326
C G+ GT C+ PC+ G G SC CP G C+ D C
Sbjct: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSC--TCPSGFSGSTCQLDVDEC 511
Score = 85.9 bits (211), Expect = 1e-16
Identities = 100/407 (24%), Positives = 126/407 (30%), Gaps = 91/407 (22%)
Query: 13 WTRGTQGSELDPKGQHVCVASSPS----AELQCCAGWRQKDQECTIPICEGPDACQKDEV 68
WT + +D VC + A C + C + + C +D +
Sbjct: 306 WTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAI 365
Query: 69 C-VKP----GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQ 121
C P +C C PGF G C G + PC G+C G+ CQC
Sbjct: 366 CDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN-----PCEHLGRCVNTQGSFLCQCG 420
Query: 122 ADRWGARCEFP---CACGP---HGRCDPATG--VCHCEPGWWSSTCRRPCQCNTAAARCE 173
G RCE C GP C G C C G+ + C + + +
Sbjct: 421 RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYC----EVDIDECQSS 476
Query: 174 QATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQ-----CECV-- 226
VCK G C+ GS C+ D CA P G +C Q C C
Sbjct: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEG 536
Query: 227 -------------------RGRC--SAASGECTCPPGFRGARCE---------------- 249
GRC AS C C PG+ G RCE
Sbjct: 537 FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK 596
Query: 250 ---------LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPG 300
CP+G+ GV C + C N PC+ C G N C C PG
Sbjct: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASN-PCTFGV-----CRDGINRYDC--VCQPG 648
Query: 301 TFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLL 347
G C + C E G C GSL PL L
Sbjct: 649 FTGPLCNVEINECASSPCGE--GGSCVDGENGFRCLCPPGSLPPLCL 693
Score = 85.9 bits (211), Expect = 1e-16
Identities = 106/404 (26%), Positives = 139/404 (34%), Gaps = 94/404 (23%)
Query: 19 GSELDPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVK---PGLC 75
GS +D +++C S P L + D P+ GP C + CV C
Sbjct: 1135 GSCIDLVARYLC--SCPPGTLGVLCEINEDDCGPGPPLDSGP-RCLHNGTCVDLVGGFRC 1191
Query: 76 RCKPGFFGAHCSSRCPGQYWGPDCRE-SCPCHPHGQC--EPATG-ACQCQADRWGARCEF 131
C PG+ G C + +CR +C C +P G C C A G RC+
Sbjct: 1192 TCPPGYTGLRCEADIN------ECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
Query: 132 ---PCA---CGPHGRCDPATG-------VCHCEPGWWSSTCRRPC------QCNTAAARC 172
PC C G+C P+ G CHC +W C R QC C
Sbjct: 1246 VLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVP-C 1304
Query: 173 EQATGA--CVCKPGWWGRRC---------SFRCNCHGSPCEQDSG----------RCACR 211
+Q C C PG G C + +C +PC RCAC
Sbjct: 1305 QQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACA 1364
Query: 212 PGWWGPECQ---------QQCECVRGRCSAASG------ECTCPP-GFRGARCELPCPAG 255
GW GP C+ ++ C R C A G EC P G+ G C L G
Sbjct: 1365 QGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSL--SVG 1422
Query: 256 SHGVQC-AHSCGRCKHNEPCSPDTGSCE------SCEPGWNGTQC----QQPCLPGTFGE 304
QC A C R +N C P S C G C ++ C
Sbjct: 1423 DPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADG 1482
Query: 305 SCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLL 348
C+Q C + E C D C S AL+A ++ L +L
Sbjct: 1483 RCDQGC----NTEECGWDGLDC----ASEVPALLARGVLVLTVL 1518
>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
domains 1 [Homo sapiens]
Length = 1138
Score = 108 bits (270), Expect = 2e-23
Identities = 52/120 (43%), Positives = 62/120 (51%), Gaps = 7/120 (5%)
Query: 210 CRPGWWGPECQQQCE-CVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC-- 265
C G WGP C ++C C+ G C GEC CPPGF G RCE C G G C C
Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274
Query: 266 -GRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
C+ C PD C SC GW G+QCQ+ C PG FG C QC C++G C+ +G
Sbjct: 275 ISGCRGLTFCLPDPYGC-SCGSGWRGSQCQEACAPGHFGADCRLQC-QCQNGGTCDRFSG 332
Score = 84.0 bits (206), Expect = 5e-16
Identities = 47/151 (31%), Positives = 64/151 (42%), Gaps = 24/151 (15%)
Query: 150 CEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCA 209
C G W C + C C G CVC PG+ G RC EQ A
Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRC-----------EQ-----A 258
Query: 210 CRPGWWGPECQQQCECVRGR-----CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
CR G +G CQ+QC + G C C+C G+RG++C+ C G G C
Sbjct: 259 CREGRFGQSCQEQCPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQ 318
Query: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
C +C++ C +G C GW+G C++
Sbjct: 319 C-QCQNGGTCDRFSGCV--CPSGWHGVHCEK 346
Score = 82.0 bits (201), Expect = 2e-15
Identities = 47/139 (33%), Positives = 61/139 (43%), Gaps = 17/139 (12%)
Query: 120 CQADRWGARCEFPC-ACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ---- 174
C A RWG C C C G C G C C PG+ + C + C+ C++
Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274
Query: 175 ---ATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RC 230
G C P +G CS GS C++ AC PG +G +C+ QC+C G C
Sbjct: 275 ISGCRGLTFCLPDPYG--CSCGSGWRGSQCQE-----ACAPGHFGADCRLQCQCQNGGTC 327
Query: 231 SAASGECTCPPGFRGARCE 249
SG C CP G+ G CE
Sbjct: 328 DRFSG-CVCPSGWHGVHCE 345
Score = 75.9 bits (185), Expect = 1e-13
Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 90 CPGQYWGPDCRESCP-CHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC--DPATG 146
C WGP C + CP C G C G C C G RCE C G G+ + G
Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPG 274
Query: 147 VCHCEPGWWSSTCRRPCQCNTA--AARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQ 203
+ C + C C + ++C++A C PG +G C +C C +G C++
Sbjct: 275 ISGCRGLTFCLPDPYGCSCGSGWRGSQCQEA-----CAPGHFGADCRLQCQCQNGGTCDR 329
Query: 204 DSGRCACRPGWWGPECQQ 221
SG C C GW G C++
Sbjct: 330 FSG-CVCPSGWHGVHCEK 346
Score = 72.0 bits (175), Expect = 2e-12
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 30/143 (20%)
Query: 59 GPDACQKDEVCVKPGLCR-------CKPGFFGAHCSSRCPGQYWGPDCRESCP----CHP 107
GP ++ C+ G+C C PGF G C C +G C+E CP C
Sbjct: 221 GPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRG 280
Query: 108 HGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNT 167
C P C C + G++C+ CA PG + + CR CQC
Sbjct: 281 LTFCLPDPYGCSCGSGWRGSQCQEACA-----------------PGHFGADCRLQCQCQN 323
Query: 168 AAARCEQATGACVCKPGWWGRRC 190
C++ +G CVC GW G C
Sbjct: 324 GGT-CDRFSG-CVCPSGWHGVHC 344
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
C G C+ C+ P C C G+ G+ C C ++G DCR C C G C+ +
Sbjct: 272 CPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFS 331
Query: 116 GACQCQADRWGARCE 130
G C C + G CE
Sbjct: 332 G-CVCPSGWHGVHCE 345
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/80 (30%), Positives = 27/80 (33%), Gaps = 14/80 (17%)
Query: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCP 311
C AG G C C C H C G C C PG G CEQ C
Sbjct: 215 CGAGRWGPGCTKECPGCLHGGVCHDHDGECV--------------CPPGFTGTRCEQACR 260
Query: 312 HCRHGEACEPDTGHCQRCSG 331
R G++C+ C G
Sbjct: 261 EGRFGQSCQEQCPGISGCRG 280
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 106 bits (265), Expect = 7e-23
Identities = 89/334 (26%), Positives = 119/334 (35%), Gaps = 80/334 (23%)
Query: 23 DPKGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDAC-QKDEVCVKPGLCRCKPGF 81
D G +VC P L C GW + C PIC C +++ C KP C C+PG+
Sbjct: 193 DHFGHYVC---QPDGNLSCLPGWT--GEYCQQPICLS--GCHEQNGYCSKPAECLCRPGW 245
Query: 82 FGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRC 141
G C+ C PH C T C P C C
Sbjct: 246 QGRLCNE----------------CIPHNGCRHGT-------------CSTPWQC----TC 272
Query: 142 DPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN-CHGSP 200
D G C+ T PC+ + Q + C C+PG+ G C + C +P
Sbjct: 273 DEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNP 332
Query: 201 C--------EQDSGRCACRPGWWGPECQQ------QCECVRG-----RCSAASGECTCPP 241
C ++D C C PG++G C+ C G R A+ C CPP
Sbjct: 333 CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPP 392
Query: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQ------- 294
F G+ CE + CA+ G+C + P + C C PG+ GT C+
Sbjct: 393 NFTGSNCEKKVDRCTSN-PCANG-GQCLNRGP----SRMCR-CRPGFTGTYCELHVSDCA 445
Query: 295 -QPCLPGTFGESCEQ----QCPHCRHGEACEPDT 323
PC G E CP G CE T
Sbjct: 446 RNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRT 479
Score = 78.2 bits (191), Expect = 3e-14
Identities = 66/256 (25%), Positives = 89/256 (34%), Gaps = 52/256 (20%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPG----LCRCKPGFFGAHCSSRCPGQYWG 96
C GW + + C C+ C G C C+PG+ G C
Sbjct: 272 CDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS----- 326
Query: 97 PDCRESCPCHPHGQCEPATGA--CQCQADRWGARCE---FPCACGP---HGRC----DPA 144
+C +S PC G C+ C C +G CE CA P G C A
Sbjct: 327 -EC-DSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGA 384
Query: 145 TGVCHCEPGWWSSTCRRP---CQCNTAA--ARC--EQATGACVCKPGWWGRRCSFRCN-- 195
C C P + S C + C N A +C + C C+PG+ G C +
Sbjct: 385 NYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC 444
Query: 196 -----CHGSPCE--QDSGRCACRPGWWGPECQQQCE---CVRGRC----------SAASG 235
HG C ++ C C G+ G C+ + C C S +
Sbjct: 445 ARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTF 504
Query: 236 ECTCPPGFRGARCELP 251
C CP GF G+RCE P
Sbjct: 505 VCNCPYGFVGSRCEFP 520
Score = 70.9 bits (172), Expect = 4e-12
Identities = 56/198 (28%), Positives = 73/198 (36%), Gaps = 56/198 (28%)
Query: 180 VCKPGWWGRRCSFRC---NCH-GSPCEQDSGRCACRPGWWGPECQQQ-----CECVRGRC 230
+C ++G CS C N H G Q G +C PGW G CQQ C G C
Sbjct: 174 ICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLSCLPGWTGEYCQQPICLSGCHEQNGYC 233
Query: 231 SAASGECTCPPGFRGARC------------------ELPCPAGSHGVQCAHSCGRCKHNE 272
S + EC C PG++G C + C G G+ C C H+
Sbjct: 234 SKPA-ECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHS 292
Query: 273 PCSPDTGSCE---------SCEPGWNGTQCQ--------QPCLPGTFGESCEQQ------ 309
PC + +C +C PG+ G C+ PC G SC+ Q
Sbjct: 293 PCK-NGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPC---RNGGSCKDQEDGYHC 348
Query: 310 -CPHCRHGEACEPDTGHC 326
CP +G CE T C
Sbjct: 349 LCPPGYYGLHCEHSTLSC 366
Score = 40.4 bits (93), Expect = 0.006
Identities = 33/115 (28%), Positives = 41/115 (35%), Gaps = 13/115 (11%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVC--VKPGL-CRCKPGFFGAHC 86
C+ PS +C G+ E + C + C C ++ GL C C GF G C
Sbjct: 417 CLNRGPSRMCRCRPGFTGTYCELHVSDC-ARNPCAHGGTCHDLENGLMCTCPAGFSGRRC 475
Query: 87 SSRCPGQYWGPDCRESCPCHPHGQC----EPATGACQCQADRWGARCEFPCACGP 137
R D S PC C T C C G+RCEFP P
Sbjct: 476 EVRT-----SIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPP 525
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 106 bits (264), Expect = 9e-23
Identities = 97/361 (26%), Positives = 127/361 (35%), Gaps = 120/361 (33%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQY----WGPDCRESCPCHPHGQ------CEPATGACQCQA 122
G C CK G C+ G Y PD C C+ G C +G C+C+A
Sbjct: 660 GQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 123 DRWGARCEF-----------------PCACGPHGR----CDPATGVCHCEP---GWWSST 158
+ G RC+ PC C HG C+P +G C C+ G T
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 159 CR-----------RPCQCNTAAAR----CEQATGACVCKPGWWGRRCS------------ 191
CR + C C+TA + C TG C+CKP GR+C+
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 192 -----FRCNC------HGS-PCEQDSGRCACRPGWWGPECQ-----------------QQ 222
CNC +GS C + +G+C C+ G G C Q
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 223 CEC-----VRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK------H 270
CEC + G C SG+C C P +G RC P A C C
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959
Query: 271 NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR-HGEACEPDTGHCQRC 329
N C+ TG C CQ + G Q+C C+ H +P TG CQ C
Sbjct: 960 NHICNSLTGQC----------VCQDASIAG-------QRCDQCKDHYFGFDPQTGRCQPC 1002
Query: 330 S 330
+
Sbjct: 1003 N 1003
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/275 (26%), Positives = 97/275 (35%), Gaps = 74/275 (26%)
Query: 68 VC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE----SCPCHPHGQ------CEPATG 116
VC K G C CKP G C+ G ++ C C G C +TG
Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866
Query: 117 ACQCQADRWGARCEF-----------------PCACGPHGR-----CDPATGVC------ 148
C C+ G RC C C G CDP +G C
Sbjct: 867 QCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNR 926
Query: 149 ------HCEPGWWSS----TCRRPCQCNTAAAR---CEQATGACVCKPGWW-GRRCSFRC 194
C+PG++ S T PC C+T A C TG CVC+ G+RC +C
Sbjct: 927 QGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD-QC 985
Query: 195 NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCE 249
H + +GRC Q C C + C +G+C C G++C+
Sbjct: 986 KDHYFGFDPQTGRC------------QPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Query: 250 LPCPAGSH-GVQCAHSCGRCKHNEPCSPDTGSCES 283
P+ SH V C + +P P G +S
Sbjct: 1034 ACVPSASHLDVNNLLGCSKTPFQQP--PPRGQVQS 1066
Score = 70.5 bits (171), Expect = 5e-12
Identities = 76/313 (24%), Positives = 104/313 (33%), Gaps = 91/313 (29%)
Query: 71 KPGLCRCKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGAR 128
+P C C F G HC RC Y R+ + C+P CQC +
Sbjct: 532 QPYRCLCSQESFTEGLHCD-RCLPLYNDKPFRQGDQVYAFN-CKP----CQCNSHSKSCH 585
Query: 129 CEFPCACGPHGRCDPATGVCH-CEPGWWSSTCR--------------------RPCQCNT 167
P GVC CE C +PC C+T
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 168 AAAR-----CEQATGACVCKPGWWGRRCS-----------------FRCNCHGS------ 199
R C+Q G C CK GR+C+ CNC+ S
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 200 -PCEQDSGRCACRPGWWGPECQ-----------------QQCEC-----VRGRCSAASGE 236
C Q+SG+C C+ G C + C+C V C+ SG+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP-------CSPDTGSCESCEPGWN 289
C C +G +C+ C +G+ +C C + C+ TG C C+P
Sbjct: 766 CECKKEAKGLQCD-TCRENFYGLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-ICKPNVE 822
Query: 290 GTQCQQPCLPGTF 302
G QC + CL G F
Sbjct: 823 GRQCNK-CLEGNF 834
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 106 bits (264), Expect = 9e-23
Identities = 97/361 (26%), Positives = 127/361 (35%), Gaps = 120/361 (33%)
Query: 73 GLCRCKPGFFGAHCSSRCPGQY----WGPDCRESCPCHPHGQ------CEPATGACQCQA 122
G C CK G C+ G Y PD C C+ G C +G C+C+A
Sbjct: 660 GQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKA 719
Query: 123 DRWGARCEF-----------------PCACGPHGR----CDPATGVCHCEP---GWWSST 158
+ G RC+ PC C HG C+P +G C C+ G T
Sbjct: 720 NVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDT 779
Query: 159 CR-----------RPCQCNTAAAR----CEQATGACVCKPGWWGRRCS------------ 191
CR + C C+TA + C TG C+CKP GR+C+
Sbjct: 780 CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQN 839
Query: 192 -----FRCNC------HGS-PCEQDSGRCACRPGWWGPECQ-----------------QQ 222
CNC +GS C + +G+C C+ G G C Q
Sbjct: 840 NSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQM 899
Query: 223 CEC-----VRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCK------H 270
CEC + G C SG+C C P +G RC P A C C
Sbjct: 900 CECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAV 959
Query: 271 NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCR-HGEACEPDTGHCQRC 329
N C+ TG C CQ + G Q+C C+ H +P TG CQ C
Sbjct: 960 NHICNSLTGQC----------VCQDASIAG-------QRCDQCKDHYFGFDPQTGRCQPC 1002
Query: 330 S 330
+
Sbjct: 1003 N 1003
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/275 (26%), Positives = 97/275 (35%), Gaps = 74/275 (26%)
Query: 68 VC-VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE----SCPCHPHGQ------CEPATG 116
VC K G C CKP G C+ G ++ C C G C +TG
Sbjct: 807 VCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTG 866
Query: 117 ACQCQADRWGARCEF-----------------PCACGPHGR-----CDPATGVC------ 148
C C+ G RC C C G CDP +G C
Sbjct: 867 QCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPNR 926
Query: 149 ------HCEPGWWSS----TCRRPCQCNTAAAR---CEQATGACVCKPGWW-GRRCSFRC 194
C+PG++ S T PC C+T A C TG CVC+ G+RC +C
Sbjct: 927 QGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD-QC 985
Query: 195 NCHGSPCEQDSGRCACRPGWWGPECQQQCEC-----VRGRCSAASGECTCPPGFRGARCE 249
H + +GRC Q C C + C +G+C C G++C+
Sbjct: 986 KDHYFGFDPQTGRC------------QPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCD 1033
Query: 250 LPCPAGSH-GVQCAHSCGRCKHNEPCSPDTGSCES 283
P+ SH V C + +P P G +S
Sbjct: 1034 ACVPSASHLDVNNLLGCSKTPFQQP--PPRGQVQS 1066
Score = 70.5 bits (171), Expect = 5e-12
Identities = 76/313 (24%), Positives = 104/313 (33%), Gaps = 91/313 (29%)
Query: 71 KPGLCRCKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGAR 128
+P C C F G HC RC Y R+ + C+P CQC +
Sbjct: 532 QPYRCLCSQESFTEGLHCD-RCLPLYNDKPFRQGDQVYAFN-CKP----CQCNSHSKSCH 585
Query: 129 CEFPCACGPHGRCDPATGVCH-CEPGWWSSTCR--------------------RPCQCNT 167
P GVC CE C +PC C+T
Sbjct: 586 YNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDT 645
Query: 168 AAAR-----CEQATGACVCKPGWWGRRCS-----------------FRCNCHGS------ 199
R C+Q G C CK GR+C+ CNC+ S
Sbjct: 646 VGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGD 705
Query: 200 -PCEQDSGRCACRPGWWGPECQ-----------------QQCEC-----VRGRCSAASGE 236
C Q+SG+C C+ G C + C+C V C+ SG+
Sbjct: 706 ITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQ 765
Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEP-------CSPDTGSCESCEPGWN 289
C C +G +C+ C +G+ +C C + C+ TG C C+P
Sbjct: 766 CECKKEAKGLQCD-TCRENFYGLDVT-NCKACDCDTAGSLPGTVCNAKTGQC-ICKPNVE 822
Query: 290 GTQCQQPCLPGTF 302
G QC + CL G F
Sbjct: 823 GRQCNK-CLEGNF 834
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 105 bits (261), Expect = 2e-22
Identities = 94/321 (29%), Positives = 118/321 (36%), Gaps = 92/321 (28%)
Query: 77 CKPGFFGAHCSSRCPGQYWGPDCR-ESC-PCH--------PHGQCEPATGAC-QCQADRW 125
C PG+ GA C G Y P ESC PC G C+ TG C +C +
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTD 878
Query: 126 GARCEF----------------PCAC---GPHGR-CDPATGVCHCEPGWWSSTCR----- 160
GA CE C C G H C TG+C C+P C
Sbjct: 879 GAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHG 938
Query: 161 ----------RPCQCNTAAARCEQAT--GACVCKPGWWGRRCSFRCNCHGSPCEQDSGRC 208
RPC C+ A + + T G C C PG G+RC RC HG QD
Sbjct: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RC-AHGFYAYQDG--- 993
Query: 209 ACRPGWWGPECQQQCEC--VRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266
+C P C+C + C +GEC CPP +G +CE C G G C
Sbjct: 994 SCTP----------CDCPHTQNTCDPETGECVCPPHTQGVKCE-ECEDGHWGYDAEVGCQ 1042
Query: 267 RC------KHNEPCSPDTGSCESCEPGWNGTQCQQ------------PC---LPGTFGES 305
C + C TG C+ C+ + G C Q PC L GT G++
Sbjct: 1043 ACNCSLVGSTHHRCDVVTGHCQ-CKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGTSGDA 1101
Query: 306 CEQQCPHCRHGEACEPDTGHC 326
C + C C +TG C
Sbjct: 1102 CNLEQGLC----GCVEETGAC 1118
Score = 101 bits (252), Expect = 2e-21
Identities = 94/364 (25%), Positives = 126/364 (34%), Gaps = 119/364 (32%)
Query: 75 CRCKPGFFGAHCSSRCPGQY------WGPDCRESCPCHPHGQCEPATGAC-QCQADRWGA 127
C C G+ G C S G Y +G C + C CH H G C C + G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGIC-QPCECHGHAAECNVHGVCIACAHNTTGV 767
Query: 128 RCE------------------FPCACGPHGRCDPATGVCH-----------CEPGWWSST 158
CE PCAC + + CH C PG+ +
Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAW 827
Query: 159 CRR-----------------PCQCN-----TAAARCEQATGACV-------------CKP 183
C R PC C+ + A C+ TG C+ C
Sbjct: 828 CERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
Query: 184 GWWGRRCSFR----CNC-----HGSPCEQDSGRCACRPGWWGPECQQQCECVRG------ 228
G++G + + C C H + C ++G C C+P G +C Q C+ G
Sbjct: 888 GFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ---CLHGYYGLDS 944
Query: 229 -------RCSAA---------SGECTCPPGFRGARCELPCPAGSHGVQCAHSCG--RCKH 270
CS A G+C C PG G RC+ C G + Q SC C H
Sbjct: 945 GHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDG-SCTPCDCPH 1002
Query: 271 NE-PCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG------EACEPDT 323
+ C P+TG C C P G +C++ C G +G E C C C+ T
Sbjct: 1003 TQNTCDPETGEC-VCPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVT 1060
Query: 324 GHCQ 327
GHCQ
Sbjct: 1061 GHCQ 1064
Score = 82.0 bits (201), Expect = 2e-15
Identities = 97/361 (26%), Positives = 126/361 (34%), Gaps = 98/361 (27%)
Query: 30 CVASSPSAELQCCAGWRQKD----QECTIPICEGPDACQKDEVC-VKPGLCRCKPGFFGA 84
C+ ++ A + CA D + C CE VC ++ GLC CKP G
Sbjct: 873 CLGNTDGAHCERCADGFYGDAVTAKNCRA--CECHVKGSHSAVCHLETGLCDCKPNVTGQ 930
Query: 85 HCSSRCPGQYWGPDCRESC-PCHPHGQCEPA---------TGACQCQADRWGARCE---- 130
C +C Y+G D C PC+ C A G C C G RC+
Sbjct: 931 QC-DQCLHGYYGLDSGHGCRPCN----CSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAH 985
Query: 131 ----------FPCACGPH--GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGA 178
PC C PH CDP TG C C P +T +CE+
Sbjct: 986 GFYAYQDGSCTPCDC-PHTQNTCDPETGECVCPP-------------HTQGVKCEE---- 1027
Query: 179 CVCKPGWWGRRCSF---RCNCH--GSP---CEQDSGRCACRPGWWGPECQQQCECVRGRC 230
C+ G WG CNC GS C+ +G C C+ + G C Q
Sbjct: 1028 --CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQ--------- 1076
Query: 231 SAASGECTCPPGFRGARCELPCPA---GSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287
C G+R +PC G+ G C G C C +TG+C C+
Sbjct: 1077 --------CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLC----GCVEETGAC-PCKEN 1123
Query: 288 WNGTQCQQPCLPGTFGESCEQQ--CPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPL 345
G QC + C GTF + C C C + C T + GS PL
Sbjct: 1124 VFGPQCNE-CREGTFALRADNPLGCSPC----FCSGLSHLCSELEDYVRTPVTLGSDQPL 1178
Query: 346 L 346
L
Sbjct: 1179 L 1179
Score = 62.4 bits (150), Expect = 1e-09
Identities = 56/203 (27%), Positives = 77/203 (37%), Gaps = 52/203 (25%)
Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRES-------------CPCHPHGQ-CEPATGAC-Q 119
C C PG G C PG + G S C C+ H C+P TG C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 120 CQADRWGARCEFPCACGPHGRCDPATGVC------HCEPGWWSSTCRRPCQCNTAAARCE 173
C + G C+ C G +G+ + C H P +S TC + RC+
Sbjct: 1422 CGDNTAGDHCDV-CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDF---RCD 1477
Query: 174 QATGACVCKPGWWGRRCSFRCNC--HGSPCEQDSGRCACRPGWWGPECQQQCEC-----V 226
C G+ G+ C RC+ +G+P + G C Q+C+C V
Sbjct: 1478 ------ACLLGYEGKHCE-RCSSSYYGNP-QTPGGSC------------QKCDCNPHGSV 1517
Query: 227 RGRCSAASGECTCPPGFRGARCE 249
G C SG+C C G G RC+
Sbjct: 1518 HGDCDRTSGQCVCRLGASGLRCD 1540
Score = 51.2 bits (121), Expect = 3e-06
Identities = 48/204 (23%), Positives = 70/204 (34%), Gaps = 47/204 (23%)
Query: 148 CHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQD-SG 206
C C G+ ++C C + R + +C+P C CHG E + G
Sbjct: 709 CECPQGYTGTSCE---SCLSGYYRVDGILFGGICQP----------CECHGHAAECNVHG 755
Query: 207 RC-ACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC 265
C AC G C+Q C PGF G P C +
Sbjct: 756 VCIACAHNTTGVHCEQ-----------------CLPGFYGEPSR-GTPGDCQPCACPLTI 797
Query: 266 GRCKHNEPCSPDTGS---CESCEPGWNGTQCQQPCLPGTFGESCE--QQCPHC------- 313
+ C + G C+ C PG++G C++ C G +G + C C
Sbjct: 798 ASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER-CADGYYGNPTVPGESCVPCDCSGNVD 856
Query: 314 -RHGEACEPDTGHCQRCSGSRDTA 336
C+ TG C +C G+ D A
Sbjct: 857 PSEAGHCDSVTGECLKCLGNTDGA 880
Score = 47.4 bits (111), Expect = 5e-05
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 21/98 (21%)
Query: 71 KPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC--EPATGACQCQADRWGAR 128
+PG C CK G+ G C RC Y SC C+P G EP TG C C+ + G
Sbjct: 423 QPGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481
Query: 129 CEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCN 166
C+ C+PG+++ + P C+
Sbjct: 482 CD------------------RCKPGFYNLKEKNPRGCS 501
Score = 46.6 bits (109), Expect = 8e-05
Identities = 59/261 (22%), Positives = 77/261 (29%), Gaps = 96/261 (36%)
Query: 56 ICEG-PDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPG---QYWGP------DCRESCPC 105
IC G +C DE K C+C+ G C+ CPG Q W P + E+C C
Sbjct: 271 ICYGHASSCPWDET-TKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 106 H--------------------PHGQCEPATGACQCQADRWGARCEF-------------- 131
H GQ C + G CE
Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPY 389
Query: 132 ------PCACGPHGRCDPA---------------TGVCHCEPGWWSSTCRR--------- 161
PC C P G G C C+ G+ C R
Sbjct: 390 EDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYP 449
Query: 162 ---PCQCN-TAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGP 217
C CN +A E TG CVCK N G C++ C+PG++
Sbjct: 450 TCVSCGCNPVGSASDEPCTGPCVCKE-----------NVEGKACDR------CKPGFYNL 492
Query: 218 ECQQQCECVRGRCSAASGECT 238
+ + C C S C+
Sbjct: 493 KEKNPRGCSECFCFGVSDVCS 513
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/134 (26%), Positives = 45/134 (33%), Gaps = 39/134 (29%)
Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHS-------------CGRCKHNEPCSPDTGSCES 283
C CPPG G C+ P G A S C H++ C P+TG C +
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 284 CEPGWNGTQCQQPCLPGTFGESCEQ-------QCPHC-------------RHGEACEP-- 321
C G C C G +G+ CPH H C+
Sbjct: 1422 CGDNTAGDHC-DVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACL 1480
Query: 322 ---DTGHCQRCSGS 332
+ HC+RCS S
Sbjct: 1481 LGYEGKHCERCSSS 1494
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 103 bits (257), Expect = 6e-22
Identities = 99/357 (27%), Positives = 114/357 (31%), Gaps = 91/357 (25%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQ-KDEVCVKPGLCRCKPGFFGAHCSSRCP-------- 91
C GW EC IC C K C PG CRC+ G+ G +C P
Sbjct: 220 CMEGWM--GPECNRAICR--QGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGI 275
Query: 92 --------------GQYWGPD---CRESCPCHPHGQCE---PATGACQCQADRWGARCEF 131
GQ D C PC G C P C C G CE
Sbjct: 276 CNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI 335
Query: 132 ---PC---ACGPHGRC-DPATGV-CHCEPGWWSSTCR------RPCQCNTAAARCEQATG 177
C C G C + + G C C PGW TC P C+ + G
Sbjct: 336 AEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNG 395
Query: 178 -ACVCKPGWWGRRCSFRCN-CHGSPCEQ--------DSGRCACRPGWWGPECQQQCECVR 227
CVC P W G+ C N C PC S C C PGW G C
Sbjct: 396 FKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL 455
Query: 228 GRCSAASG--------ECTCPPGFRGARCEL--------PCPAGSHGVQCAHSCGRCKHN 271
G+C + C CPPG+ G CE PC G H C + R +
Sbjct: 456 GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGH---CQNEINRFQCL 512
Query: 272 EP-------CSPDTGSCESCEPGWNGTQCQQ-------PCLPGTFGESCEQQCPHCR 314
P C D CE P NG QC C G++C HCR
Sbjct: 513 CPTGFSGNLCQLDIDYCEP-NPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 96.3 bits (238), Expect = 9e-20
Identities = 100/387 (25%), Positives = 127/387 (32%), Gaps = 121/387 (31%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKD-------EVCVKPGLCRCKPGFFGAHCSSRCPGQ 93
C G + +C G C KD + C+ G C G CS CP
Sbjct: 271 CVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCS-NTGPDKYQCS--CPEG 327
Query: 94 YWGPDCR---ESC---PCHPHGQC-EPATG-ACQCQADRWGARCEF------PCACGPHG 139
Y GP+C +C PCH G C E + G C+C G C P C G
Sbjct: 328 YSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGG 387
Query: 140 RC-DPATGV-CHCEPGWWSSTCR--------RPCQCNTAAARCEQATGACVCKPGWWGRR 189
C D G C C P W TC+ +PC N + + A+ C C PGW G+
Sbjct: 388 TCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPC-VNAKSCKNLIASYYCDCLPGWMGQN 446
Query: 190 CSFRCNCHGSPCEQDSG--------RCACRPGWWGPECQQQC-ECVRGRCSAASG----- 235
C N C+ D+ RC C PG+ G C++ EC C
Sbjct: 447 CDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEI 506
Query: 236 ---ECTCPPGFRGARCEL-------------------------PCPAGSHGVQCAHSCGR 267
+C CP GF G C+L CP G C+H
Sbjct: 507 NRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDH 566
Query: 268 CKHNEPC-----------SPDT---------------GSCES---------CEPGWNGTQ 292
C+ PC S DT G C+S C G+ GT
Sbjct: 567 CR-TTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTY 625
Query: 293 CQQPCLPGTFGESCEQQCPHCRHGEAC 319
C + CE CR+G C
Sbjct: 626 CHENI------NDCESN--PCRNGGTC 644
Score = 84.7 bits (208), Expect = 3e-16
Identities = 87/319 (27%), Positives = 115/319 (36%), Gaps = 86/319 (26%)
Query: 57 CEGPDACQKDEVC---VKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
CE + C+ C V C C G+ GA+C + DC ++ PCH G C
Sbjct: 633 CES-NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIN------DCSQN-PCHNGGTCRD 684
Query: 114 ATGA--CQCQADRWGARCEFPCACGPHGRCDPAT----GVCH---------CEPGWWSST 158
C C+ G C +CD AT G C+ C GW +T
Sbjct: 685 LVNDFYCDCKNGWKGKTCH-----SRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTT 739
Query: 159 CR---------RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN-CHGSPCEQDSG-- 206
C PC N + CVCK GW G C+ N C PC +SG
Sbjct: 740 CNIARNSSCLPNPCH-NGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC-YNSGTC 797
Query: 207 -------RCACRPGWWGPECQQQC-ECVRGRCSAASG--------ECTCPPGFRGARCE- 249
RC C PG+ GP+C+ EC C+ + C CPPG GA+C+
Sbjct: 798 VDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQE 857
Query: 250 ---LPC-PAGS---HGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
PC GS G + C C+ C +C W G +PCL
Sbjct: 858 VSGRPCITMGSVIPDGAKWDDDCNTCQ----C---LNGRIACSKVWCG---PRPCL---- 903
Query: 303 GESCEQQCPHCRHGEACEP 321
+ C G++C P
Sbjct: 904 ---LHKGHSECPSGQSCIP 919
Score = 57.4 bits (137), Expect = 5e-08
Identities = 53/190 (27%), Positives = 72/190 (37%), Gaps = 32/190 (16%)
Query: 166 NTAAARCEQATGACVCKPGWWGRRCSFRCNCHGS-----PCEQDSGRCACRPGWWGPE-- 218
NT A E C ++G C+ C C+Q+ G C GW GPE
Sbjct: 173 NTGVAHFEYQIRV-TCDDYYYGFGCNKFCRPRDDFFGHYACDQN-GNKTCMEGWMGPECN 230
Query: 219 ---CQQQCECVRGRCSAASGECTCPPGFRGARCE--LPCPAGSHGV-----QCAHSCGRC 268
C+Q C G C G+C C G++G C+ +P P HG+ QC C
Sbjct: 231 RAICRQGCSPKHGSCK-LPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCL--CETN 287
Query: 269 KHNEPCSPDTGSCESCEPGWNGTQC--------QQPCLPGTFGESCEQQCPHCRHGEACE 320
+ C D C + +P NG C Q C G G +CE H + C
Sbjct: 288 WGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE-IAEHACLSDPCH 346
Query: 321 PDTGHCQRCS 330
+ G C+ S
Sbjct: 347 -NRGSCKETS 355
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 103 bits (257), Expect = 6e-22
Identities = 104/389 (26%), Positives = 131/389 (33%), Gaps = 81/389 (20%)
Query: 29 VCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCV-KPG--LCRCKPGFFGAH 85
+CV S PS C G++ + + CE CQ C+ +P LC+C PG+ G +
Sbjct: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP-CQNGATCMAQPSGYLCQCAPGYDGQN 964
Query: 86 CSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCE--------FPCAC 135
CS D +S PCH HG C P G C C G RCE PC
Sbjct: 965 CSKEL-------DACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
Query: 136 GPHGRCDPATGV--CHCEPGWWSSTCR---RPCQCNTA--AARCEQATGA-----CVCKP 183
C C C PG C PC CE G+ C C
Sbjct: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPK 1077
Query: 184 GWWGRRCSFRC------NCH------GSPCEQDSGRCACRPGWWGPEC-----QQQC--- 223
G+ G CS R +CH SP RCAC G+ GP+C + C
Sbjct: 1078 GFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
Query: 224 -ECV-RGRCSAASG------ECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCS 275
C+ G CS +G C+CP G RC+ P G G +C +
Sbjct: 1138 SPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
Query: 276 PDTGSCESCEPG-WNGTQCQQPCLPGTFGESCEQQCP---------HCRHGEACEP---- 321
D G C P W G C C QC C AC P
Sbjct: 1198 WDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQ 1257
Query: 322 ------DTGHCQRCSGSRDTALIAGSLVP 344
GHC++ + + G P
Sbjct: 1258 YCHDHFHNGHCEKGCNTAECGWDGGDCRP 1286
Score = 100 bits (248), Expect = 6e-21
Identities = 86/286 (30%), Positives = 108/286 (37%), Gaps = 67/286 (23%)
Query: 75 CRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGA--CQCQADRWGARCEF- 131
C C PGF G C +CR S PC GQC+ GA C+C G RC+
Sbjct: 537 CICLPGFSGTRCEEDID------ECRSS-PCANGGQCQDQPGAFHCKCLPGFEGPRCQTE 589
Query: 132 -------PCACGPHGRCDPATGVCHCEPGWWSSTCRRP-CQCNTAAAR--C--EQATGAC 179
PC G P C C G+ C P C N + C ++ C
Sbjct: 590 VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANC 649
Query: 180 VCKPGWWGRRCS---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQC-ECVRGRCS---- 231
+C G G C+ C CH C++ S C C GW GPEC+ + C+ C+
Sbjct: 650 LCPDGSPG--CAPPEDNCTCHHGHCQRSS--CVCDVGWTGPECEAELGGCISAPCAHGGT 705
Query: 232 ----AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGS--CESCE 285
+ CTCP G+ G C S + HS G C + C+P G C +C
Sbjct: 706 CYPQPSGYNCTCPTGYTGPTC-------SEEMTACHS-GPCLNGGSCNPSPGGYYC-TCP 756
Query: 286 PGWNGTQCQ--------QPCL--------PGTFGESCEQ--QCPHC 313
P G QCQ PC PGTF C Q P C
Sbjct: 757 PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRC 802
Score = 99.4 bits (246), Expect = 1e-20
Identities = 106/402 (26%), Positives = 137/402 (34%), Gaps = 132/402 (32%)
Query: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCR 100
C GW T P CE C G C +P G +C+ CP Y GP C
Sbjct: 679 CDVGW-------TGPECEAELGGCISAPCAHGGTCYPQPS--GYNCT--CPTGYTGPTCS 727
Query: 101 E------SCPCHPHGQCEPATGA--CQCQADRWGARCEF--------PCACGPHGRC--D 142
E S PC G C P+ G C C G +C+ PC G G C
Sbjct: 728 EEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNG--GTCVNR 785
Query: 143 PATGVCHCEPGWWSSTCR---------RPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
P T C C G+ C PC+ N A + C+C G+ G C
Sbjct: 786 PGTFSCLCAMGFQGPRCEGKLRPSCADSPCR-NRATCQDSPQGPRCLCPTGYTGGSCQTL 844
Query: 194 CN-CHGSPCEQDSG--------RCACRPGWWGPECQ---QQCE-------------CVRG 228
+ C PC ++S C C GW GP C C+ C G
Sbjct: 845 MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
Query: 229 RCSAASGE---CTCPPGFRGARCE--------LPCPAGS--------HGVQCA-----HS 264
SG C CPPGF+G+ C+ PC G+ + QCA +
Sbjct: 905 GLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQN 964
Query: 265 CGR---------CKHNEPCSPDTGSCE-SCEPGWNGTQCQ--------QP---------- 296
C + C ++ C+P G +C PG+ G +C+ QP
Sbjct: 965 CSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACH 1024
Query: 297 ---------CLPGTFGESCEQQCPHCR-----HGEACEPDTG 324
CLPG G+ CE + C HG CE G
Sbjct: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAG 1066
Score = 98.6 bits (244), Expect = 2e-20
Identities = 94/345 (27%), Positives = 124/345 (35%), Gaps = 103/345 (29%)
Query: 60 PDACQKDEVCVK----PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
P+ C C+ G C+C PGF G C P C+ + C G C+
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-------CQNAQLCQNGGSCQAL- 83
Query: 116 GACQCQADRWGARCEFPCACGPHGRCDPATG--VCHCEPGWWSSTCRR----PCQCNTAA 169
P G P T +C C PG+ C+ PC + +
Sbjct: 84 ---------------LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCS 128
Query: 170 --ARCE-QATGA--CVCKPGWWGRRCSFRCNCHGSPCEQDSG--------RCACRPGWWG 216
RC QA+G C C PGW G +C R C +PC +C C PG+ G
Sbjct: 129 KRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEG 188
Query: 217 PECQQQC-ECVR--GRC--------SAASGECTCPPGFRGARCEL---PCP--AGSHGVQ 260
C++ EC + G C + S +C CP G G RCEL PCP S+G
Sbjct: 189 HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGT 248
Query: 261 CA---------HSC--------------------GRCKHNEPCSP--DTGSCESCEPGWN 289
C H C +C++ C DT +C C W
Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC-LCPETWT 307
Query: 290 GTQCQQPCLPGTFGESCEQQ-CPHCRHGEACEPDTG--HCQRCSG 331
G C + + CE Q PHCR+G C+ G HC SG
Sbjct: 308 GWDCSEDV------DECETQGPPHCRNGGTCQNSAGSFHCVCVSG 346
Score = 96.3 bits (238), Expect = 9e-20
Identities = 99/361 (27%), Positives = 128/361 (35%), Gaps = 76/361 (21%)
Query: 30 CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVK---PGLCRCKPGFFGAHC 86
C S+ S C +GW E + C C C+ C C PG G C
Sbjct: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAA-TCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
Query: 87 SSRCPGQYWGPDCRESCPCHPHGQCE--PATGA--CQCQADRWGARC-----------EF 131
D S PCH QC P TG+ C CQ G C +
Sbjct: 391 HLE--------DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG 442
Query: 132 PCACGPHGRC--DPATGVCHCEPGWWSSTCR--------RPCQCNTAAARCEQATGACVC 181
P C G C P + C C PG+ S C +PC + AT C+C
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL-LATFHCLC 501
Query: 182 KPGWWGRRCSFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQQQCECVRGRCSA 232
PG G+ C N C +PC + +C C PG+ G C++ + R A
Sbjct: 502 PPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCA 561
Query: 233 ASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES--------C 284
G+C PG +C LP G G +C C ++PC P SC C
Sbjct: 562 NGGQCQDQPGAFHCKC-LP---GFEGPRCQTEVDECL-SDPC-PVGASCLDLPGAFFCLC 615
Query: 285 EPGWNGTQCQQP-CLPGTF--GESCEQQ-------CPHCRHG-----EACEPDTGHCQRC 329
G+ G C+ P C P + C+ Q CP G + C GHCQR
Sbjct: 616 PSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS 675
Query: 330 S 330
S
Sbjct: 676 S 676
Score = 85.5 bits (210), Expect = 2e-16
Identities = 93/328 (28%), Positives = 114/328 (34%), Gaps = 89/328 (27%)
Query: 58 EGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRE------SCPCHPHGQC 111
E D C+ C G C+ +PG F HC +C + GP C+ S PC C
Sbjct: 550 EDIDECRSSP-CANGGQCQDQPGAF--HC--KCLPGFEGPRCQTEVDECLSDPCPVGASC 604
Query: 112 EPATGA--CQCQADRWGARCEFP-CA---CGPHGRC----DPATGVCH-----CEPGWWS 156
GA C C + G CE P CA C P C D A +C C P +
Sbjct: 605 LDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN 664
Query: 157 STC------RRPCQCNTA--AARCEQATGACV--------------------CKPGWWGR 188
TC R C C+ CE G C+ C G+ G
Sbjct: 665 CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP 724
Query: 189 RCSFRCN-CHGSPCEQDSG--------RCACRPGWWGPECQQQCE-CVRGRC-------- 230
CS CH PC C C P GP+CQ + CV C
Sbjct: 725 TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVN 784
Query: 231 SAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPC--SPDTGSCESCEPGW 288
+ C C GF+G RCE G CA S C++ C SP C C G+
Sbjct: 785 RPGTFSCLCAMGFQGPRCE-----GKLRPSCADS--PCRNRATCQDSPQGPRC-LCPTGY 836
Query: 289 NGTQCQQPCLPGTFGESCEQQ-CPHCRH 315
G CQ T + C Q+ CP H
Sbjct: 837 TGGSCQ------TLMDLCAQKPCPRNSH 858
Score = 65.1 bits (157), Expect = 2e-10
Identities = 64/216 (29%), Positives = 78/216 (36%), Gaps = 43/216 (19%)
Query: 131 FPCACGPHGRC---DPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWG 187
FP C G C G C C PG+ TC+ P C A C+ P G
Sbjct: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQN-AQLCQNGGSCQALLPAPLG 89
Query: 188 RRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCE--------CVRGRCSA-ASG--E 236
S SP S C C PG+ G CQ + E RGRC ASG +
Sbjct: 90 LPSS------PSPLTP-SFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
Query: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP 296
C+C PG+ G +C+L C N PC + G C + P Q Q
Sbjct: 143 CSCMPGWTGEQCQLR--------------DFCSAN-PCV-NGGVCLATYP-----QIQCH 181
Query: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGS 332
C PG G +CE+ C P C GS
Sbjct: 182 CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 102 bits (254), Expect = 1e-21
Identities = 83/285 (29%), Positives = 101/285 (35%), Gaps = 79/285 (27%)
Query: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC-RESCPCHPHGQCEPATGACQCQ 121
C + C+ G C C PGF G PDC R+SCP G E G C C+
Sbjct: 536 CNGNGECIS-GHCHCFPGFLG-------------PDCARDSCPVLCGGNGEYEKGHCVCR 581
Query: 122 ADRWGARCEFP-------------------CACGP-------------------HGRCDP 143
G C+ P C C P HG C
Sbjct: 582 HGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSNHGIC-- 639
Query: 144 ATGVCHCEPGWWSSTCRRPC-----QCNTAAARCEQATGACVCKPGWWGRRCS-----FR 193
G CHC GW C P QC+ A G C C P W G CS
Sbjct: 640 VKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDA-GVCSCDPKWTGSDCSTELCTME 698
Query: 194 CNCHGSPCEQDSGRCACRPGWWGPECQQQ---CECV-RGRCSAASGECTCPPGFRGARCE 249
C HG C + G C C GW GP C+++ C G+C G+C C PG+ G C
Sbjct: 699 CGSHG-VCSR--GICQCEEGWVGPTCEERSCHSHCTEHGQCK--DGKCECSPGWEGDHCT 753
Query: 250 LPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCES-CEPGWNGTQC 293
+ + C G C N C+ D C+ GW+GT C
Sbjct: 754 IAHYLDAVRDGCP---GLCFGNGRCTLDQNGWHCVCQVGWSGTGC 795
Score = 96.7 bits (239), Expect = 7e-20
Identities = 71/234 (30%), Positives = 86/234 (36%), Gaps = 40/234 (17%)
Query: 41 CCAGWRQKDQECTIPI--CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPD 98
C GW K EC +P C P C C+ G+C C PG+ G C D
Sbjct: 580 CRHGW--KGPECDVPEEQCIDP-TCFGHGTCIM-GVCICVPGYKGEICEEE--------D 627
Query: 99 CRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA-----CGPHGRCDPATGVCHCEPG 153
C + C HG C G C C G CE P C HG GVC C+P
Sbjct: 628 CLDPM-CSNHGIC--VKGECHCSTGWGGVNCETPLPVCQEQCSGHGTFLLDAGVCSCDPK 684
Query: 154 WWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDS---GRCAC 210
W S C + + G C C+ GW G C R +CH E G+C C
Sbjct: 685 WTGSDCSTELCTMECGSHGVCSRGICQCEEGWVGPTCEER-SCHSHCTEHGQCKDGKCEC 743
Query: 211 RPGWWGPEC--QQQCECVR----------GRCSAASG--ECTCPPGFRGARCEL 250
PGW G C + VR GRC+ C C G+ G C +
Sbjct: 744 SPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQVGWSGTGCNV 797
Score = 90.1 bits (222), Expect = 7e-18
Identities = 62/196 (31%), Positives = 78/196 (39%), Gaps = 36/196 (18%)
Query: 56 ICEGPDA----CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQC 111
ICE D C +CVK G C C G+ G +C + P C+E C HG
Sbjct: 622 ICEEEDCLDPMCSNHGICVK-GECHCSTGWGGVNCETPLPV------CQEQCS--GHGTF 672
Query: 112 EPATGACQCQADRWGARCEFPCA---CGPHGRCDPATGVCHCEPGWWSSTCR-RPCQCN- 166
G C C G+ C CG HG C + G+C CE GW TC R C +
Sbjct: 673 LLDAGVCSCDPKWTGSDCSTELCTMECGSHGVC--SRGICQCEEGWVGPTCEERSCHSHC 730
Query: 167 TAAARCEQATGACVCKPGWWGRRCSF-------RCNCHG-------SPCEQDSGRCACRP 212
T +C+ G C C PGW G C+ R C G +Q+ C C+
Sbjct: 731 TEHGQCKD--GKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 213 GWWGPECQQQCECVRG 228
GW G C E + G
Sbjct: 789 GWSGTGCNVVMEMLCG 804
Score = 89.4 bits (220), Expect = 1e-17
Identities = 64/226 (28%), Positives = 85/226 (37%), Gaps = 47/226 (20%)
Query: 135 CGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF-- 192
C +G C +G CHC PG+ C R E G CVC+ GW G C
Sbjct: 536 CNGNGEC--ISGHCHCFPGFLGPDCARDSCPVLCGGNGEYEKGHCVCRHGWKGPECDVPE 593
Query: 193 ------RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCS----AASGECTCPPG 242
C HG+ G C C PG+ G C+++ +C+ CS GEC C G
Sbjct: 594 EQCIDPTCFGHGTCI---MGVCICVPGYKGEICEEE-DCLDPMCSNHGICVKGECHCSTG 649
Query: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ------- 295
+ G CE P P +C + D G C SC+P W G+ C
Sbjct: 650 WGGVNCETPLPVCQE---------QCSGHGTFLLDAGVC-SCDPKWTGSDCSTELCTMEC 699
Query: 296 -----------PCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCS 330
C G G +CE++ H E + G C+ CS
Sbjct: 700 GSHGVCSRGICQCEEGWVGPTCEERSCHSHCTEHGQCKDGKCE-CS 744
Score = 72.4 bits (176), Expect = 1e-12
Identities = 60/224 (26%), Positives = 81/224 (36%), Gaps = 44/224 (19%)
Query: 22 LDP--KGQHVCVASSPSAELQCCAGWRQKDQECTIPICEGPDACQ-KDEVCVKPGLCRCK 78
LDP +CV E C GW + E +P+C+ + C + G+C C
Sbjct: 629 LDPMCSNHGICV----KGECHCSTGWGGVNCETPLPVCQ--EQCSGHGTFLLDAGVCSCD 682
Query: 79 PGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCA---C 135
P + G+ CS+ C + C HG C + G CQC+ G CE C
Sbjct: 683 PKWTGSDCSTEL--------C--TMECGSHGVC--SRGICQCEEGWVGPTCEERSCHSHC 730
Query: 136 GPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARC------------EQATGACVCKP 183
HG+C G C C PGW C + C +Q CVC+
Sbjct: 731 TEHGQC--KDGKCECSPGWEGDHCTIAHYLDAVRDGCPGLCFGNGRCTLDQNGWHCVCQV 788
Query: 184 GWWGRRCS--FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCEC 225
GW G C+ C + G C P+C QQ C
Sbjct: 789 GWSGTGCNVVMEMLCGDNLDNDGDGLTDC----VDPDCCQQSNC 828
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,745,870
Number of Sequences: 37866
Number of extensions: 2459398
Number of successful extensions: 21205
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 952
Number of HSP's that attempted gapping in prelim test: 11804
Number of HSP's gapped (non-prelim): 4548
length of query: 744
length of database: 18,247,518
effective HSP length: 110
effective length of query: 634
effective length of database: 14,082,258
effective search space: 8928151572
effective search space used: 8928151572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.