Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 14249150

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249150 single stranded DNA binding protein 4 isoform a
[Homo sapiens]
         (385 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14249150 single stranded DNA binding protein 4 isoform a [Hom...   818   0.0  
gi|58218984 single stranded DNA binding protein 4 isoform b [Hom...   754   0.0  
gi|21955170 single stranded DNA binding protein 3 isoform a [Hom...   607   e-174
gi|21314684 single stranded DNA binding protein 3 isoform b [Hom...   565   e-161
gi|58218981 single stranded DNA binding protein 3 isoform c [Hom...   563   e-160
gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]      560   e-160
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 82   6e-16
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    82   8e-16
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    82   8e-16
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    82   8e-16
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       81   1e-15
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      80   4e-15
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    79   9e-15
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    79   9e-15
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        78   1e-14
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    77   2e-14
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        77   3e-14
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        77   3e-14
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    75   8e-14
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                75   1e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     75   1e-13
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      74   2e-13
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       74   2e-13
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     74   2e-13
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          74   2e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    74   3e-13
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            73   4e-13
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    73   5e-13
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    73   5e-13
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    73   5e-13

>gi|14249150 single stranded DNA binding protein 4 isoform a [Homo
           sapiens]
          Length = 385

 Score =  818 bits (2113), Expect = 0.0
 Identities = 385/385 (100%), Positives = 385/385 (100%)

Query: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60
           MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120
           HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 121 FFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA 180
           FFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA
Sbjct: 121 FFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA 180

Query: 181 MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR 240
           MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR
Sbjct: 181 MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR 240

Query: 241 GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300
           GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA
Sbjct: 241 GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300

Query: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG 360
           GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG
Sbjct: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG 360

Query: 361 EMAAAGTFLHPFPSESYSPGMTMSV 385
           EMAAAGTFLHPFPSESYSPGMTMSV
Sbjct: 361 EMAAAGTFLHPFPSESYSPGMTMSV 385


>gi|58218984 single stranded DNA binding protein 4 isoform b [Homo
           sapiens]
          Length = 363

 Score =  754 bits (1947), Expect = 0.0
 Identities = 363/385 (94%), Positives = 363/385 (94%), Gaps = 22/385 (5%)

Query: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60
           MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60

Query: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120
           HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG
Sbjct: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120

Query: 121 FFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA 180
           FFQ                      PFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA
Sbjct: 121 FFQ----------------------PFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA 158

Query: 181 MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR 240
           MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR
Sbjct: 159 MEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVR 218

Query: 241 GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300
           GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA
Sbjct: 219 GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA 278

Query: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG 360
           GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG
Sbjct: 279 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDG 338

Query: 361 EMAAAGTFLHPFPSESYSPGMTMSV 385
           EMAAAGTFLHPFPSESYSPGMTMSV
Sbjct: 339 EMAAAGTFLHPFPSESYSPGMTMSV 363


>gi|21955170 single stranded DNA binding protein 3 isoform a [Homo
           sapiens]
          Length = 388

 Score =  607 bits (1566), Expect = e-174
 Identities = 285/394 (72%), Positives = 329/394 (83%), Gaps = 15/394 (3%)

Query: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59

Query: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119

Query: 121 FFQGPPGSQPS------PHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174
           FFQGPPGSQPS      PHNP++ MMGPH QPFMSPR+ GGPRP +RM +QPP G+PG+Q
Sbjct: 120 FFQGPPGSQPSPHAQPPPHNPSS-MMGPHSQPFMSPRYAGGPRPPIRMGNQPPGGVPGTQ 178

Query: 175 PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPA 232
           PLLP +M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P 
Sbjct: 179 PLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPG 236

Query: 233 MNMGPGVRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYT 291
           +NMGPG   PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT
Sbjct: 237 INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 296

Query: 292 IMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351
           ++NP+  G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN
Sbjct: 297 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISN 356

Query: 352 APGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 385
            PGTPRDDGE+   G FLH F +++YSP MTMSV
Sbjct: 357 PPGTPRDDGEL--GGNFLHSFQNDNYSPSMTMSV 388


>gi|21314684 single stranded DNA binding protein 3 isoform b [Homo
           sapiens]
          Length = 368

 Score =  565 bits (1457), Expect = e-161
 Identities = 272/394 (69%), Positives = 313/394 (79%), Gaps = 35/394 (8%)

Query: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59

Query: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119

Query: 121 FFQGPPGSQPS------PHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174
           FFQGPPGSQPS      PHNP++ MMGPH                    SQPP G+PG+Q
Sbjct: 120 FFQGPPGSQPSPHAQPPPHNPSS-MMGPH--------------------SQPPGGVPGTQ 158

Query: 175 PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPA 232
           PLLP +M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P 
Sbjct: 159 PLLPNSMDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPG 216

Query: 233 MNMGPGVRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYT 291
           +NMGPG   PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT
Sbjct: 217 INMGPGAGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYT 276

Query: 292 IMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351
           ++NP+  G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN
Sbjct: 277 MINPVPPGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISN 336

Query: 352 APGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 385
            PGTPRDDGE+   G FLH F +++YSP MTMSV
Sbjct: 337 PPGTPRDDGEL--GGNFLHSFQNDNYSPSMTMSV 368


>gi|58218981 single stranded DNA binding protein 3 isoform c [Homo
           sapiens]
          Length = 361

 Score =  563 bits (1450), Expect = e-160
 Identities = 267/388 (68%), Positives = 309/388 (79%), Gaps = 30/388 (7%)

Query: 1   MYAKGGKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGFL 60
           M+AKG KGSAVPSD QAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGFL
Sbjct: 1   MFAKG-KGSAVPSDGQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFL 59

Query: 61  HSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAG 120
           HSWWCVFWDLYCAAP+RR+ CEHS EAKAF DYSAAAAPSPV+G++ P D M  G +  G
Sbjct: 60  HSWWCVFWDLYCAAPERRDTCEHSSEAKAFHDYSAAAAPSPVLGNIPPNDGMPGGPIPPG 119

Query: 121 FFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA 180
           FF                      QPFMSPR+ GGPRP +RM +QPP G+PG+QPLLP +
Sbjct: 120 FF----------------------QPFMSPRYAGGPRPPIRMGNQPPGGVPGTQPLLPNS 157

Query: 181 MEPSPRAQGHPSMGGPMQRVTPPRGMASV--GPQSYGGGMRPPPNSLAGPGLPAMNMGPG 238
           M+P+ R QGHP+MGG MQR+ PPRGM  +  GPQ+YG GMRPPPNSL GP +P +NMGPG
Sbjct: 158 MDPT-RQQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPPPNSL-GPAMPGINMGPG 215

Query: 239 VRGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIG 297
              PW +P S NSIPYSSSSPG+Y GPPGGGGPPGTPIMPSP DSTNSS+N+YT++NP+ 
Sbjct: 216 AGRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVP 275

Query: 298 QGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPR 357
            G  R+NFP+GPG +GPM  M  MEPHH+NGSLGSGD+DGLPK+SP  ++G+SN PGTPR
Sbjct: 276 PGGSRSNFPMGPGSDGPMGGMGGMEPHHMNGSLGSGDIDGLPKNSPNNISGISNPPGTPR 335

Query: 358 DDGEMAAAGTFLHPFPSESYSPGMTMSV 385
           DDGE+   G FLH F +++YSP MTMSV
Sbjct: 336 DDGEL--GGNFLHSFQNDNYSPSMTMSV 361


>gi|40787999 single-stranded DNA binding protein 2 [Homo sapiens]
          Length = 361

 Score =  560 bits (1443), Expect = e-160
 Identities = 269/387 (69%), Positives = 303/387 (78%), Gaps = 28/387 (7%)

Query: 1   MYAKG-GKGSAVPSDSQAREKLALYVYEYLLHIGAQKSAQTFLSEIRWEKNITLGEPPGF 59
           MY KG    SAVPSDSQAREKLALYVYEYLLH+GAQKSAQTFLSEIRWEKNITLGEPPGF
Sbjct: 1   MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGF 60

Query: 60  LHSWWCVFWDLYCAAPDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAA 119
           LHSWWCVFWDLYCAAP+RRE CEHS EAKAF DYSAAAAPSPV+G++ PGD M  G +  
Sbjct: 61  LHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNIPPGDGMPVGPVPP 120

Query: 120 GFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPG 179
           GFF                      QPFMSPR+PGGPRP LR+P+Q   G+PGSQPLLP 
Sbjct: 121 GFF----------------------QPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPS 158

Query: 180 AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGV 239
            M+P+ R QGHP+MGGPMQR+TPPRGM  +GPQ+YGG MRPP N+L GPG+P MNMGPG 
Sbjct: 159 GMDPT-RQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGG 217

Query: 240 RGPWASP-SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQ 298
             PW +P + NSIPYSS+SPG+Y GPPGGGGPPGTPIMPSP DSTNS +NMYT+MN +  
Sbjct: 218 GRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPP 277

Query: 299 GAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRD 358
           G  R NFP+GPG +GPM  +  ME HH+NGSLGSGDMD + K+SP  ++ LSN PGTPRD
Sbjct: 278 GPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMS-LSNQPGTPRD 336

Query: 359 DGEMAAAGTFLHPFPSESYSPGMTMSV 385
           DGEM   G FL+PF SESYSP MTMSV
Sbjct: 337 DGEM--GGNFLNPFQSESYSPSMTMSV 361


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 79/262 (30%), Positives = 100/262 (38%), Gaps = 16/262 (6%)

Query: 123  QGPPGSQPSPHNPNAP-MMGPHGQPFMSPR-----FPGGPRPTLRMPSQPPAGLPGSQPL 176
            +GPPG    P  P      GP G P    R      PG P   +         +PG  P 
Sbjct: 766  RGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP-PG 824

Query: 177  LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMG 236
             PGAM P P   G P   GP         +   GP    G   PP  S+ GP  P    G
Sbjct: 825  PPGAMGP-PGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPG 883

Query: 237  PGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP-IMPSPGDSTNSSENMYTIMNP 295
             G+ GP   P      + S+S    +GPPG  GPPG       PG   +  E      + 
Sbjct: 884  EGLPGPPGPPGS----FLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFST 939

Query: 296  IGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLG--SGDMDGLPKSSPGAVAGLSNAP 353
             G  +   N    PGP GP           V G+LG  SG  +G   SS   V+G    P
Sbjct: 940  SGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEG-GSSSTMYVSGPPGPP 998

Query: 354  GTPRDDGEMAAAGTFLHPFPSE 375
            G P   G ++++G  +  + SE
Sbjct: 999  GPPGPPGSISSSGQEIQQYISE 1020



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 87/288 (30%), Positives = 104/288 (36%), Gaps = 39/288 (13%)

Query: 124 GPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP 183
           GPPGS        A   GPHG P +    PG   P     S  P G PG  P+    +  
Sbjct: 636 GPPGSGEKGERGAAGEPGPHGPPGV----PGSVGPKGSSGSPGPQGPPG--PVGLQGLRG 689

Query: 184 SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPNSLAGPGL--------PAM 233
                G     GPM    P       GP+   G  GMR  P ++  PG         P  
Sbjct: 690 EVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDG 749

Query: 234 NMGP-GVRGPWASPSGNSIPYSSSSPG--SYTGPPGGGGPPGTPIMP-------SPGD-S 282
           + GP G +G    P     P  S  PG    TGP G  G PGTP  P       +PG   
Sbjct: 750 HQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIV 809

Query: 283 TNSSENMYTIMNPIGQ--GAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP- 339
           T+   +M T+  P G     G    P  PGP GP       E  ++ G  G     G P 
Sbjct: 810 TSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPG 869

Query: 340 KSSPGAVA-------GLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
            S PG          GL   PG P     ++ + TFL   P     PG
Sbjct: 870 PSIPGPPGPRGPPGEGLPGPPGPP--GSFLSNSETFLSGPPGPPGPPG 915



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 76/233 (32%), Positives = 91/233 (39%), Gaps = 17/233 (7%)

Query: 95   AAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM----GPHGQPFMSP 150
            A   P P       G     G       QGPPG  P P  P  P +    GP G P    
Sbjct: 828  AMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGP-PGPRGPPGPSIPGPPGPRGPP--GE 884

Query: 151  RFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRA-QGHPSMGGPMQRVTPPRGMASV 209
              PG P P     S     L G  P  PG   P P+  QG P   G       P G ++ 
Sbjct: 885  GLPGPPGPPGSFLSNSETFLSGP-PGPPGP--PGPKGDQGPPGPRGHQGEQGLP-GFSTS 940

Query: 210  GPQSYGGGMRPPPNSLAGPGLPAMNMG-PGVRGPWASPSGNSIPYSSSSPGSYTGPPGGG 268
            G  S+G  ++ PP    GP  P  + G PGV G    PSG S    SSS    +GPPG  
Sbjct: 941  GSSSFGLNLQGPPGP-PGPQGPKGDKGDPGVPGALGIPSGPS-EGGSSSTMYVSGPPGPP 998

Query: 269  GPPGTP-IMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG-PGPEGPMAAMS 319
            GPPG P  + S G       + Y   + I         P G PGP GP+  ++
Sbjct: 999  GPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTIT 1051



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 84/316 (26%), Positives = 104/316 (32%), Gaps = 49/316 (15%)

Query: 95  AAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMS----P 150
           AA  P P      PG     GS  +   QGPPG           + G  G P +     P
Sbjct: 648 AAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQG-----LRGEVGLPGVKGDKGP 702

Query: 151 RFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVG 210
             P GP+       + P GL G     PG M   P A G P   G M    P       G
Sbjct: 703 MGPPGPKGD--QGEKGPRGLTGE----PG-MRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755

Query: 211 PQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYT------ 262
            Q   G  G+R PP     PG P +    G +G   +P    I     +PG         
Sbjct: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815

Query: 263 --------GPPGGGGPPGTPIMPSPGDSTN--SSENMYTIMNPIG----QGAGRANFPLG 308
                   GPPG  GPPG P  P P         + +  +  P G    +G    + P  
Sbjct: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGP 875

Query: 309 PGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTF 368
           PGP GP        P         G       +S   ++G    PG P   G+    G  
Sbjct: 876 PGPRGPPGEGLPGPP---------GPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPR 926

Query: 369 LHPFPSESYSPGMTMS 384
            H    E   PG + S
Sbjct: 927 GH--QGEQGLPGFSTS 940



 Score = 36.2 bits (82), Expect = 0.051
 Identities = 40/137 (29%), Positives = 49/137 (35%), Gaps = 39/137 (28%)

Query: 237 PGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPI 296
           PG +G   SP                GP G  G PGTP +P P            + +P 
Sbjct: 569 PGPKGDMGSP----------------GPKGDRGFPGTPGIPGP------------LGHPG 600

Query: 297 GQGAGRANFPLG-PGPEGPMAAMSA---MEPHHVNGSLGSGDMDGLPKSSPGAVA--GLS 350
            QG       +G PG EGPM        M P    G  GSG+     K   GA    G  
Sbjct: 601 PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGE-----KGERGAAGEPGPH 655

Query: 351 NAPGTPRDDGEMAAAGT 367
             PG P   G   ++G+
Sbjct: 656 GPPGVPGSVGPKGSSGS 672



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 47/155 (30%), Positives = 60/155 (38%), Gaps = 28/155 (18%)

Query: 212  QSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPP 271
            + Y  G R PP     PG  A   G  +   +A  S   + Y SSS G   G PG  GPP
Sbjct: 1101 RQYLMGPRGPPGP---PG--ASGDGSLLSLDYAELSSRILSYMSSS-GISIGLPGPPGPP 1154

Query: 272  GTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLG 331
            G P          S E + +++    +G+        PGP GP        P +V  S+ 
Sbjct: 1155 GLP--------GTSYEELLSLL----RGSEFRGIVGPPGPPGPPGI-----PGNVWSSIS 1197

Query: 332  SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
              D+     SS    AGLS  PG P   G     G
Sbjct: 1198 VEDL-----SSYLHTAGLSFIPGPPGPPGPPGPRG 1227



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 9/130 (6%)

Query: 237  PGVRGPWASPSGNSIPYSSSSPGS----YTGPPGGGGPPGTPIMPSPGDSTNSSENMYTI 292
            PG  GP   P  +     S   GS      GPPG  GPPG   +P    S+ S E++ + 
Sbjct: 1148 PGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPG---IPGNVWSSISVEDLSSY 1204

Query: 293  MNPIGQG--AGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLS 350
            ++  G     G    P  PGP GP     A+  +    S           +SP   + + 
Sbjct: 1205 LHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIV 1264

Query: 351  NAPGTPRDDG 360
              PG P   G
Sbjct: 1265 GPPGPPGPQG 1274



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 51/213 (23%), Positives = 76/213 (35%), Gaps = 29/213 (13%)

Query: 159  TLRMPSQP-PAGLPGSQ-----PLLPGA----MEPSPRAQGHPSMGGPMQRVTPPRGMAS 208
            ++ +P  P P GLPG+       LL G+    +   P   G P + G    V     +  
Sbjct: 1144 SIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPG---NVWSSISVED 1200

Query: 209  VGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYT------ 262
            +    +  G+   P     PG P     PGV G  A+ +  +     S   SY       
Sbjct: 1201 LSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVR 1260

Query: 263  -------GPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAG-RANFPLGPGPEGP 314
                   GPPG  GPPG   + S   S +   +  +  + + +G+   ++   G G  G 
Sbjct: 1261 SFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGS 1320

Query: 315  MAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA 347
            + A  A       G  G    D  P    GA A
Sbjct: 1321 LGAGGAF--GEAAGDRGPYGTDIGPGGGYGAAA 1351



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 10/89 (11%)

Query: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDG----LPKSSPGAVAGLSNAPGTP 356
           G   FP  PG  GP+       P    GS+G   M+G      +  P    G +  PG+ 
Sbjct: 582 GDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGS- 640

Query: 357 RDDGEMAAAGTFLHPFPSESYSPGMTMSV 385
            + GE  AAG      P     PG+  SV
Sbjct: 641 GEKGERGAAGE-----PGPHGPPGVPGSV 664


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 90/294 (30%), Positives = 107/294 (36%), Gaps = 49/294 (16%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-------MMGPHGQPFMSPRFPGGP-RPT 159
           PG     G    G   GPPG +  P  P  P        +G  G P   P FPG    P 
Sbjct: 695 PGSKGEPGIPGIGL-PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG-PPGFPGPKGEPG 752

Query: 160 LRMPSQP-PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQR-----VTPPRGMASVGPQS 213
             +P  P P GLPG +    GA+ P    +G P   GP  R     +  P+G   VGP  
Sbjct: 753 FALPGPPGPPGLPGFK----GALGPKGD-RGFPGPPGPPGRTGLDGLPGPKG--DVGPNG 805

Query: 214 YGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG----SYTGPPGGGG 269
             G M PP   L G G+      PG+ GP   P  + IP     PG       GPPG  G
Sbjct: 806 QPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PG P  P P             + P G     G+A     PG +G M  M    P    
Sbjct: 864 SPGIPGAPGP-------------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 328 GSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
           G  G   + GL         GL   PG P   GE  + G    P P     P +
Sbjct: 911 GIPGRSGVPGLKGDD-----GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 90/320 (28%), Positives = 115/320 (35%), Gaps = 69/320 (21%)

Query: 124  GPPGSQPSPHNPNAP-MMGPHGQPFMSPR-----FPG--GPRPTLRMPSQP-PAGLPG-- 172
            GPPG + SP  P AP  +GP G P +  +     FPG  G    +  P  P P G+PG  
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 173  ------------SQPLLPGAMEPSPRAQGHPSMGGPMQRVTP----------PRGMASV- 209
                         QP LPG       ++G P + GP   + P            G+  + 
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKG-SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 210  ---GPQSYGG--------------GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIP 252
               GP+ Y G              G+  PP     PGLP     PG+ GP     G    
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ---PGLIGP-PGLKGTIGD 1031

Query: 253  YSSSSPGSYTGPPGGGGPPGTPIMPS-------PGDSTNSSENMYTIMNPIGQGAGRANF 305
                 P    GPPG  G PG P  P         GD   SS  +  +  P G+  G   +
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE-PGLPGY 1090

Query: 306  PLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKS-SPGAVAGLSNAPGTPRDDGEMAA 364
            P  PG +G +            G+ G   + G P +  P    G+S  PG P   GE   
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 365  AGTFLHPF----PSESYSPG 380
             G   HP     P E   PG
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPG 1170



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 80/271 (29%), Positives = 104/271 (38%), Gaps = 31/271 (11%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHG-------QPFMSPRFPGGPRPT 159
            PGD    G        GPPG + +P  P  P ++GP G         F  P+   GP   
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 160  LRMPSQPPA-GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-- 216
              +P QP + GLPG +       +P   + G P + GP      P    + G +   G  
Sbjct: 1047 SGVPGQPGSPGLPGQKG---DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 217  ---GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGT 273
               G+   P +   PGLP     PG  GP   P G S P  +       GP GGGG PG 
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGF---PGTPGP-PGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 274  PIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLG 331
            P    PG+     ++   I  P GQ    G+  F   PGP G            + G  G
Sbjct: 1160 P--GPPGEKGKPGQD--GIPGPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 332  SGDMDGLPKSSPG--AVAGLSNAPGTPRDDG 360
            +  + G PK  PG     G+   PG P   G
Sbjct: 1215 NPGLPG-PKGEPGFHGFPGVQGPPGPPGSPG 1244



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 87/279 (31%), Positives = 105/279 (37%), Gaps = 46/279 (16%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP---MMGPHGQPFMSPRFPGG-PRPT---- 159
            PG+    G      F G PG Q  P  P +P   + GP G P   P+ P G P PT    
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP--GPQGPPGRPGPTGFQG 1270

Query: 160  LRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMR 219
            L  P  PP GLPG+  +     + +P   G P + G      PP    + G        R
Sbjct: 1271 LPGPEGPP-GLPGNGGIK--GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG--------R 1319

Query: 220  PPPNSLAG-PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS 278
            P  N + G PGLP +   PG++GP   P        S+ P    G PG  GPPG P +P 
Sbjct: 1320 PGLNGMKGDPGLPGVPGFPGMKGPSGVPG-------SAGP---EGEPGLIGPPGPPGLPG 1369

Query: 279  PGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMD 336
            P      S     I    G     G+      PGP+GP        P    G  G    D
Sbjct: 1370 P------SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423

Query: 337  GL--PKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
            G    K  P    GL   PGT   DG     G    P P
Sbjct: 1424 GAGGRKGDP----GLPGQPGTRGLDGPPGPDGLQGPPGP 1458



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 92/316 (29%), Positives = 113/316 (35%), Gaps = 60/316 (18%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPG--GP 156
           P P      PG     G   A   +G PG   +P  P  P  G  G+P     FPG  G 
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP--GSKGEPGDILTFPGMKGD 559

Query: 157 RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG 216
           +  L  P  P  GLPG    LPG    +P   G P + GP      P G+   G      
Sbjct: 560 KGELGSPGAP--GLPG----LPG----TPGQDGLPGLPGPKGE---PGGITFKGE----- 601

Query: 217 GMRPPPNSLAGPGLPAMNMGP---------------GVRGPWASPSGNSIPYSSSSPGSY 261
             R PP +   PGLP  N+GP               G++G   +P    IP     PG  
Sbjct: 602 --RGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 262 TGPPGGGGPPGTP----IMPSPGDSTNSSENMYTIMNPIGQGAGRANFP-LG-PGPEGPM 315
              PG  G PG P     +  PGD     +     +  I    G    P +G PGP GP 
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ---PGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 316 AAMSAMEPHHVNGSLGSGDMDGL--------PKSSPG-AVAGLSNAPGTPRDDGEMAAAG 366
                  P    G+ G   ++G         PK  PG A+ G    PG P   G +   G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 367 TFLHPFPSESYSPGMT 382
                FP     PG T
Sbjct: 776 D--RGFPGPPGPPGRT 789



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/299 (29%), Positives = 106/299 (35%), Gaps = 53/299 (17%)

Query: 97   AAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPF-MSPR 151
            A P P      PG   A G      F GPPG          P     +GP+GQP  M P 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP- 812

Query: 152  FPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGP 211
             PG P   ++ P  PP G+PG  P+    +   P  +G P   G +    PP    S G 
Sbjct: 813  -PGLPGIGVQGPPGPP-GIPG--PIGQPGLHGIPGEKGDPGPPG-LDVPGPPGERGSPGI 867

Query: 212  QSYGGGMRPP-----PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPG 266
                G + PP     P      G P      G+ GP   P    IP  S  PG   G  G
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG-LKGDDG 926

Query: 267  GGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHV 326
              G PG P                    P G+  G    P  PGP GP      M+P ++
Sbjct: 927  LQGQPGLP-------------------GPTGE-KGSKGEPGLPGPPGP------MDP-NL 959

Query: 327  NGSLGSGDMDGLP----KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
             GS G     GLP     S P    GL   PG P   G+    G      P    +PG+
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP-----PGPKGNPGL 1013



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 79/275 (28%), Positives = 97/275 (35%), Gaps = 44/275 (16%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQP-FMSPRFP 153
            P PV G   PG              GPPG +  P     P      G  GQP F +P  P
Sbjct: 1148 PGPVGGGGHPGQ------------PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 154  GGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQS 213
            G P  + +       G+PG+ P LPG  +  P   G P + GP      P G A  GP+ 
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGN-PGLPGP-KGEPGFHGFPGVQGPPGPPGSP-GPALEGPKG 1252

Query: 214  YGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG-----SYTGPPGGG 268
              G   PP      PG       PG  GP   P    I     +PG        G  G  
Sbjct: 1253 NPGPQGPP----GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1308

Query: 269  GPPGTPIMPS-PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVN 327
            GPPG    P  PG            +N +    G    P  PG +GP     +  P    
Sbjct: 1309 GPPGLQGNPGRPG------------LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1356

Query: 328  GSLGSGDMDGLPKSSPGA--VAGLSNAPGTPRDDG 360
            G +G     GLP  S  +  + G +  PG P   G
Sbjct: 1357 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1391



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 79/264 (29%), Positives = 98/264 (37%), Gaps = 41/264 (15%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQPFMSPR-------FPGGPRPTLRMPSQPPAGLPG--S 173
           +G PG +  P  P  P  GP G P   PR        PG P P      + P GLPG   
Sbjct: 50  RGFPGLEGHPGLPGFP--GPEGPP--GPRGQKGDDGIPGPPGPK---GIRGPPGLPGFPG 102

Query: 174 QPLLPG--AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPPNSLA 226
            P LPG    + +P  QG P   G       P      G Q   G     GM+  P S+ 
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII 162

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMPSPGDSTN 284
              LP     PG  GP   P    +P  +  PG     GPPG  GPPG P +P P  +  
Sbjct: 163 MSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 285 SSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-KSSP 343
                     P G+  G       PGP G ++     +   ++     GD  GLP    P
Sbjct: 220 -----LNFQGPKGE-KGEQGLQGPPGPPGQISE----QKRPIDVEFQKGD-QGLPGDRGP 268

Query: 344 GAVAGLSNAPGTP-RDDGEMAAAG 366
               G+   PG P  + GE    G
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 77/256 (30%), Positives = 90/256 (35%), Gaps = 29/256 (11%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPP 167
           PG     G       QGPPG    P  P A +MGP G P     FPG  R        P 
Sbjct: 364 PGLPGEKGERGFPGIQGPPGL---PGPPGAAVMGPPGPP----GFPG-ERGQKGDEGPPG 415

Query: 168 AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG-MASVGPQSYGGGMRPPPNSLA 226
             +PG     P  ++  P A G P   GP     PP   +   GP         PP S  
Sbjct: 416 ISIPG-----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG-------PPGS-- 461

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP-SPGDSTNS 285
            PG   +    GV+G       N I    S P    G PG  GPPG+   P   G+   +
Sbjct: 462 -PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 286 SENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGA 345
                  +  I    G   FP   G  G +     M+     G LGS    GLP   PG 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD--KGELGSPGAPGLP-GLPG- 576

Query: 346 VAGLSNAPGTPRDDGE 361
             G    PG P   GE
Sbjct: 577 TPGQDGLPGLPGPKGE 592



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 86/308 (27%), Positives = 101/308 (32%), Gaps = 40/308 (12%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
           PG     GS+      GP G+   P  P    + GP G P   P  P GP   +  P   
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP--GPIGPPGPPGLMGPPG-- 207

Query: 167 PAGLPGSQPLL------PGAMEPSPRAQGHPSMGGPMQRVTPPRGMA-SVGPQSYGGGMR 219
           P GLPG +  +      P   +     QG P   G +     P  +    G Q   G   
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 220 P--PPNSLAGPGLPAMNMG-------PGVRGPWASPSGNSIPYSSSSPG--SYTGPP--- 265
           P  PP     PG P    G       PG RG       N  P     PG   Y G P   
Sbjct: 268 PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 266 ------GGGGPPGTP--IMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG---- 313
                 G  GPPG P  ++P PG      E     +  +    G   FP   GP G    
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 314 -PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
              A M    P    G  G    +G P  S     GL   PG P   G    AG  + P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP- 446

Query: 373 PSESYSPG 380
             E   PG
Sbjct: 447 SDEICEPG 454



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 86/300 (28%), Positives = 104/300 (34%), Gaps = 71/300 (23%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM-------GPHGQPFMSPR-----FPGGP 156
           GD    G       +GPPG    P  P  P M       GP G P  +       FPG P
Sbjct: 78  GDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP 137

Query: 157 R-PTLRMPSQPPAGLPGSQPLLPGA--MEPSPRAQGHPSMGGP--MQRVTPPRGM-ASVG 210
             P L+ P  PP G+PG +   PG+  M   P  +G+P   GP  +Q +  P G+   +G
Sbjct: 138 GFPGLQGPPGPP-GIPGMKG-EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 211 PQSYGGGMRPPPNSLAGPGLPAM--NMGPGVRGPWASPSGNSIPYSSSSPGSYT------ 262
           P    G M PP      PGLP    NMG   +GP        +      PG  +      
Sbjct: 196 PPGPPGLMGPP----GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 263 ---------GPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG 313
                    G PG  GPPG P +  P               P G   G       PG  G
Sbjct: 252 DVEFQKGDQGLPGDRGPPGPPGIRGP-------------PGPPGGEKGEKGEQGEPGKRG 298

Query: 314 PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                        +G  G   + GLP   PG        PG P  DGE    G    P P
Sbjct: 299 KPGK---------DGENGQPGIPGLP-GDPG-------YPGEPGRDGEKGQKGDTGPPGP 341



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 53/158 (33%), Positives = 61/158 (38%), Gaps = 12/158 (7%)

Query: 123  QGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPG--SQPLLPG 179
            QGPPG Q +P  P    M G  G P + P FPG   P+    S  P G PG    P  PG
Sbjct: 1308 QGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1366

Query: 180  AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGV 239
               PS ++       GP      P      GPQ    G +  P     PG P  N  PG 
Sbjct: 1367 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ----GPQGLPGPTGPPGDPGRNGLPGF 1422

Query: 240  RGPWASPSGNSIPYSSSSPGSYTGPPGGGG---PPGTP 274
             G         +P    + G   GPPG  G   PPG P
Sbjct: 1423 DGAGGRKGDPGLPGQPGTRG-LDGPPGPDGLQGPPGPP 1459



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/168 (30%), Positives = 59/168 (35%), Gaps = 18/168 (10%)

Query: 217 GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIM 276
           G R  P     PGLP      G  GP      + IP     P    GPPG  G PGTP +
Sbjct: 48  GERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP-GPPGPKGIRGPPGLPGFPGTPGL 106

Query: 277 PS-PG-DSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGS 332
           P  PG D     + +       G+    G   FP   GP GP           + G  GS
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG------MKGEPGS 160

Query: 333 GDMDGL--PKSSPG-----AVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
             M  L  PK +PG      + GL    G P   G     G    P P
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGP 208


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 90/294 (30%), Positives = 107/294 (36%), Gaps = 49/294 (16%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-------MMGPHGQPFMSPRFPGGP-RPT 159
           PG     G    G   GPPG +  P  P  P        +G  G P   P FPG    P 
Sbjct: 695 PGSKGEPGIPGIGL-PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG-PPGFPGPKGEPG 752

Query: 160 LRMPSQP-PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQR-----VTPPRGMASVGPQS 213
             +P  P P GLPG +    GA+ P    +G P   GP  R     +  P+G   VGP  
Sbjct: 753 FALPGPPGPPGLPGFK----GALGPKGD-RGFPGPPGPPGRTGLDGLPGPKG--DVGPNG 805

Query: 214 YGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG----SYTGPPGGGG 269
             G M PP   L G G+      PG+ GP   P  + IP     PG       GPPG  G
Sbjct: 806 QPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PG P  P P             + P G     G+A     PG +G M  M    P    
Sbjct: 864 SPGIPGAPGP-------------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 328 GSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
           G  G   + GL         GL   PG P   GE  + G    P P     P +
Sbjct: 911 GIPGRSGVPGLKGDD-----GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 89/297 (29%), Positives = 111/297 (37%), Gaps = 57/297 (19%)

Query: 98   APSPVMGSMAPGDTMAAGSMAAGFF-----------QGPPGSQPSPHNPNAPMM----GP 142
            AP P+    +PG    AG  A+GF             GPPG    P     P +    G 
Sbjct: 870  APGPIGPPGSPGLPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 143  HGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP----SPRAQGHPSMGGPMQ 198
             GQP       G P PT    S+   GLPG     PG M+P    S   +G P + G + 
Sbjct: 928  QGQP-------GLPGPTGEKGSKGEPGLPGP----PGPMDPNLLGSKGEKGEPGLPG-IP 975

Query: 199  RVTPPRGMASV----GPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIP 252
             V+ P+G   +    G     G  G+  PP     PGLP     PG+ GP     G    
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ---PGLIGP-PGLKGTIGD 1031

Query: 253  YSSSSPGSYTGPPGGGGPPGTPIMPS-PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGP 311
                 P    GPPG  G PG P  P  PG   +  +           G      P  PGP
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD----------PGISSIGLPGLPGP 1081

Query: 312  EGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA--GLSNAPGTPRDDGEMAAAG 366
            +G            + GS+G   + GLP  +PGA    GL   PGTP   G    +G
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLP-GTPGAKGQPGLPGFPGTPGPPGPKGISG 1137



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 82/287 (28%), Positives = 99/287 (34%), Gaps = 45/287 (15%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM----GPHGQPFMSPRFPGGPRPTLRMP 163
            PG     G      + G PG + S  +P  P +    G  GQP + P FPG P P     
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPPGPKG 1134

Query: 164  SQPPAGLPGSQPLLPGAMEPSP-RAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPP 222
               P G PG    LPG  EP P    GHP   GP      P      GP    G    P 
Sbjct: 1135 ISGPPGNPG----LPG--EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 223  NSLAGP-------------GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGP----- 264
                GP             GLP +   PG+ GP   P  +  P     PG    P     
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE 1248

Query: 265  -----PGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMS 319
                 PG  GPPG P +P P        N        G   G    P  PG  G      
Sbjct: 1249 GPKGNPGPQGPPGRPGLPGPEGPPGLPGN--------GGIKGEKGNPGQPGLPGLPGLKG 1300

Query: 320  AMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
               P  + G+ G   ++G+ K  PG + G+   PG     G   +AG
Sbjct: 1301 DQGPPGLQGNPGRPGLNGM-KGDPG-LPGVPGFPGMKGPSGVPGSAG 1345



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 86/274 (31%), Positives = 104/274 (37%), Gaps = 42/274 (15%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP---MMGPHGQPFMSPRFPGGPRPTLRMPS 164
            PG+    G      F G PG Q  P  P +P   + GP G P   P+ P G RP L  P 
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP--GPQGPPG-RPGLPGPE 1269

Query: 165  QPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNS 224
             PP GLPG+  +     + +P   G P + G      PP    + G        RP  N 
Sbjct: 1270 GPP-GLPGNGGIK--GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG--------RPGLNG 1318

Query: 225  LAG-PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDST 283
            + G PGLP +   PG++GP   P        S+ P    G PG  GPPG P +P P    
Sbjct: 1319 MKGDPGLPGVPGFPGMKGPSGVPG-------SAGP---EGEPGLIGPPGPPGLPGP---- 1364

Query: 284  NSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGL--P 339
              S     I    G     G+      PGP+GP        P    G  G    DG    
Sbjct: 1365 --SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR 1422

Query: 340  KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
            K  P    GL   PGT   DG     G    P P
Sbjct: 1423 KGDP----GLPGQPGTRGLDGPPGPDGLQGPPGP 1452



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 80/271 (29%), Positives = 104/271 (38%), Gaps = 31/271 (11%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHG-------QPFMSPRFPGGPRPT 159
            PGD    G        GPPG + +P  P  P ++GP G         F  P+   GP   
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGP 1046

Query: 160  LRMPSQPPA-GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-- 216
              +P QP + GLPG +       +P   + G P + GP      P    + G +   G  
Sbjct: 1047 SGVPGQPGSPGLPGQKG---DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103

Query: 217  ---GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGT 273
               G+   P +   PGLP     PG  GP   P G S P  +       GP GGGG PG 
Sbjct: 1104 GLPGLPGTPGAKGQPGLPGF---PGTPGP-PGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 274  PIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLG 331
            P    PG+     ++   I  P GQ    G+  F   PGP G            + G  G
Sbjct: 1160 P--GPPGEKGKPGQD--GIPGPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 332  SGDMDGLPKSSPG--AVAGLSNAPGTPRDDG 360
            +  + G PK  PG     G+   PG P   G
Sbjct: 1215 NPGLPG-PKGEPGFHGFPGVQGPPGPPGSPG 1244



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 92/316 (29%), Positives = 113/316 (35%), Gaps = 60/316 (18%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPG--GP 156
           P P      PG     G   A   +G PG   +P  P  P  G  G+P     FPG  G 
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP--GSKGEPGDILTFPGMKGD 559

Query: 157 RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG 216
           +  L  P  P  GLPG    LPG    +P   G P + GP      P G+   G      
Sbjct: 560 KGELGSPGAP--GLPG----LPG----TPGQDGLPGLPGPKGE---PGGITFKGE----- 601

Query: 217 GMRPPPNSLAGPGLPAMNMGP---------------GVRGPWASPSGNSIPYSSSSPGSY 261
             R PP +   PGLP  N+GP               G++G   +P    IP     PG  
Sbjct: 602 --RGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 262 TGPPGGGGPPGTP----IMPSPGDSTNSSENMYTIMNPIGQGAGRANFP-LG-PGPEGPM 315
              PG  G PG P     +  PGD     +     +  I    G    P +G PGP GP 
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ---PGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 316 AAMSAMEPHHVNGSLGSGDMDGL--------PKSSPG-AVAGLSNAPGTPRDDGEMAAAG 366
                  P    G+ G   ++G         PK  PG A+ G    PG P   G +   G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 367 TFLHPFPSESYSPGMT 382
                FP     PG T
Sbjct: 776 D--RGFPGPPGPPGRT 789



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 78/271 (28%), Positives = 100/271 (36%), Gaps = 42/271 (15%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQP-FMSPRFP 153
            P PV G   PG              GPPG +  P     P      G  GQP F +P  P
Sbjct: 1148 PGPVGGGGHPGQ------------PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 154  GGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQS 213
            G P  + +       G+PG+ P LPG  +  P   G P + GP      P G A  GP+ 
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGN-PGLPGP-KGEPGFHGFPGVQGPPGPPGSP-GPALEGPKG 1252

Query: 214  YGGGMRPPPN-SLAGP-GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPP 271
              G   PP    L GP G P +    G++G   +P    +P      G   GPPG  G P
Sbjct: 1253 NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD-QGPPGLQGNP 1311

Query: 272  GTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLG 331
            G P                  +N +    G    P  PG +GP     +  P    G +G
Sbjct: 1312 GRP-----------------GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG 1354

Query: 332  SGDMDGLPKSSPGA--VAGLSNAPGTPRDDG 360
                 GLP  S  +  + G +  PG P   G
Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1385



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/299 (29%), Positives = 106/299 (35%), Gaps = 53/299 (17%)

Query: 97   AAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPF-MSPR 151
            A P P      PG   A G      F GPPG          P     +GP+GQP  M P 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP- 812

Query: 152  FPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGP 211
             PG P   ++ P  PP G+PG  P+    +   P  +G P   G +    PP    S G 
Sbjct: 813  -PGLPGIGVQGPPGPP-GIPG--PIGQPGLHGIPGEKGDPGPPG-LDVPGPPGERGSPGI 867

Query: 212  QSYGGGMRPP-----PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPG 266
                G + PP     P      G P      G+ GP   P    IP  S  PG   G  G
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG-LKGDDG 926

Query: 267  GGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHV 326
              G PG P                    P G+  G    P  PGP GP      M+P ++
Sbjct: 927  LQGQPGLP-------------------GPTGE-KGSKGEPGLPGPPGP------MDP-NL 959

Query: 327  NGSLGSGDMDGLP----KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
             GS G     GLP     S P    GL   PG P   G+    G      P    +PG+
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP-----PGPKGNPGL 1013



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 79/264 (29%), Positives = 98/264 (37%), Gaps = 41/264 (15%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQPFMSPR-------FPGGPRPTLRMPSQPPAGLPG--S 173
           +G PG +  P  P  P  GP G P   PR        PG P P      + P GLPG   
Sbjct: 50  RGFPGLEGHPGLPGFP--GPEGPP--GPRGQKGDDGIPGPPGPK---GIRGPPGLPGFPG 102

Query: 174 QPLLPG--AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPPNSLA 226
            P LPG    + +P  QG P   G       P      G Q   G     GM+  P S+ 
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII 162

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMPSPGDSTN 284
              LP     PG  GP   P    +P  +  PG     GPPG  GPPG P +P P  +  
Sbjct: 163 MSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 285 SSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-KSSP 343
                     P G+  G       PGP G ++     +   ++     GD  GLP    P
Sbjct: 220 -----LNFQGPKGE-KGEQGLQGPPGPPGQISE----QKRPIDVEFQKGD-QGLPGDRGP 268

Query: 344 GAVAGLSNAPGTP-RDDGEMAAAG 366
               G+   PG P  + GE    G
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 77/256 (30%), Positives = 90/256 (35%), Gaps = 29/256 (11%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPP 167
           PG     G       QGPPG    P  P A +MGP G P     FPG  R        P 
Sbjct: 364 PGLPGEKGERGFPGIQGPPGL---PGPPGAAVMGPPGPP----GFPG-ERGQKGDEGPPG 415

Query: 168 AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG-MASVGPQSYGGGMRPPPNSLA 226
             +PG     P  ++  P A G P   GP     PP   +   GP         PP S  
Sbjct: 416 ISIPG-----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG-------PPGS-- 461

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP-SPGDSTNS 285
            PG   +    GV+G       N I    S P    G PG  GPPG+   P   G+   +
Sbjct: 462 -PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 286 SENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGA 345
                  +  I    G   FP   G  G +     M+     G LGS    GLP   PG 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD--KGELGSPGAPGLP-GLPG- 576

Query: 346 VAGLSNAPGTPRDDGE 361
             G    PG P   GE
Sbjct: 577 TPGQDGLPGLPGPKGE 592



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 86/308 (27%), Positives = 101/308 (32%), Gaps = 40/308 (12%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
           PG     GS+      GP G+   P  P    + GP G P   P  P GP   +  P   
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP--GPIGPPGPPGLMGPPG-- 207

Query: 167 PAGLPGSQPLL------PGAMEPSPRAQGHPSMGGPMQRVTPPRGMA-SVGPQSYGGGMR 219
           P GLPG +  +      P   +     QG P   G +     P  +    G Q   G   
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 220 P--PPNSLAGPGLPAMNMG-------PGVRGPWASPSGNSIPYSSSSPG--SYTGPP--- 265
           P  PP     PG P    G       PG RG       N  P     PG   Y G P   
Sbjct: 268 PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 266 ------GGGGPPGTP--IMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG---- 313
                 G  GPPG P  ++P PG      E     +  +    G   FP   GP G    
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 314 -PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
              A M    P    G  G    +G P  S     GL   PG P   G    AG  + P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP- 446

Query: 373 PSESYSPG 380
             E   PG
Sbjct: 447 SDEICEPG 454



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 86/300 (28%), Positives = 104/300 (34%), Gaps = 71/300 (23%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM-------GPHGQPFMSPR-----FPGGP 156
           GD    G       +GPPG    P  P  P M       GP G P  +       FPG P
Sbjct: 78  GDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP 137

Query: 157 R-PTLRMPSQPPAGLPGSQPLLPGA--MEPSPRAQGHPSMGGP--MQRVTPPRGM-ASVG 210
             P L+ P  PP G+PG +   PG+  M   P  +G+P   GP  +Q +  P G+   +G
Sbjct: 138 GFPGLQGPPGPP-GIPGMKG-EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 211 PQSYGGGMRPPPNSLAGPGLPAM--NMGPGVRGPWASPSGNSIPYSSSSPGSYT------ 262
           P    G M PP      PGLP    NMG   +GP        +      PG  +      
Sbjct: 196 PPGPPGLMGPP----GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 263 ---------GPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG 313
                    G PG  GPPG P +  P               P G   G       PG  G
Sbjct: 252 DVEFQKGDQGLPGDRGPPGPPGIRGP-------------PGPPGGEKGEKGEQGEPGKRG 298

Query: 314 PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                        +G  G   + GLP   PG        PG P  DGE    G    P P
Sbjct: 299 KPGK---------DGENGQPGIPGLP-GDPG-------YPGEPGRDGEKGQKGDTGPPGP 341



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 53/158 (33%), Positives = 61/158 (38%), Gaps = 12/158 (7%)

Query: 123  QGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPG--SQPLLPG 179
            QGPPG Q +P  P    M G  G P + P FPG   P+    S  P G PG    P  PG
Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1360

Query: 180  AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGV 239
               PS ++       GP      P      GPQ    G +  P     PG P  N  PG 
Sbjct: 1361 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ----GPQGLPGPTGPPGDPGRNGLPGF 1416

Query: 240  RGPWASPSGNSIPYSSSSPGSYTGPPGGGG---PPGTP 274
             G         +P    + G   GPPG  G   PPG P
Sbjct: 1417 DGAGGRKGDPGLPGQPGTRG-LDGPPGPDGLQGPPGPP 1453



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/168 (30%), Positives = 59/168 (35%), Gaps = 18/168 (10%)

Query: 217 GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIM 276
           G R  P     PGLP      G  GP      + IP     P    GPPG  G PGTP +
Sbjct: 48  GERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP-GPPGPKGIRGPPGLPGFPGTPGL 106

Query: 277 PS-PG-DSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGS 332
           P  PG D     + +       G+    G   FP   GP GP           + G  GS
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG------MKGEPGS 160

Query: 333 GDMDGL--PKSSPG-----AVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
             M  L  PK +PG      + GL    G P   G     G    P P
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGP 208


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 90/294 (30%), Positives = 107/294 (36%), Gaps = 49/294 (16%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-------MMGPHGQPFMSPRFPGGP-RPT 159
           PG     G    G   GPPG +  P  P  P        +G  G P   P FPG    P 
Sbjct: 695 PGSKGEPGIPGIGL-PGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG-PPGFPGPKGEPG 752

Query: 160 LRMPSQP-PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQR-----VTPPRGMASVGPQS 213
             +P  P P GLPG +    GA+ P    +G P   GP  R     +  P+G   VGP  
Sbjct: 753 FALPGPPGPPGLPGFK----GALGPKGD-RGFPGPPGPPGRTGLDGLPGPKG--DVGPNG 805

Query: 214 YGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG----SYTGPPGGGG 269
             G M PP   L G G+      PG+ GP   P  + IP     PG       GPPG  G
Sbjct: 806 QPGPMGPP--GLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERG 863

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PG P  P P             + P G     G+A     PG +G M  M    P    
Sbjct: 864 SPGIPGAPGP-------------IGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 328 GSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
           G  G   + GL         GL   PG P   GE  + G    P P     P +
Sbjct: 911 GIPGRSGVPGLKGDD-----GLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 89/297 (29%), Positives = 111/297 (37%), Gaps = 57/297 (19%)

Query: 98   APSPVMGSMAPGDTMAAGSMAAGFF-----------QGPPGSQPSPHNPNAPMM----GP 142
            AP P+    +PG    AG  A+GF             GPPG    P     P +    G 
Sbjct: 870  APGPIGPPGSPGLPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 143  HGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP----SPRAQGHPSMGGPMQ 198
             GQP       G P PT    S+   GLPG     PG M+P    S   +G P + G + 
Sbjct: 928  QGQP-------GLPGPTGEKGSKGEPGLPGP----PGPMDPNLLGSKGEKGEPGLPG-IP 975

Query: 199  RVTPPRGMASV----GPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIP 252
             V+ P+G   +    G     G  G+  PP     PGLP     PG+ GP     G    
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ---PGLIGP-PGLKGTIGD 1031

Query: 253  YSSSSPGSYTGPPGGGGPPGTPIMPS-PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGP 311
                 P    GPPG  G PG P  P  PG   +  +           G      P  PGP
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD----------PGISSIGLPGLPGP 1081

Query: 312  EGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA--GLSNAPGTPRDDGEMAAAG 366
            +G            + GS+G   + GLP  +PGA    GL   PGTP   G    +G
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLP-GTPGAKGQPGLPGFPGTPGPPGPKGISG 1137



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 91/326 (27%), Positives = 117/326 (35%), Gaps = 74/326 (22%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNA-PMMGPHGQPFMSPRFPG--GPRPTLRMPS 164
            PG T   GS       GPPG    P +PN     G  G+P + P  PG  GP+    +P 
Sbjct: 934  PGPTGEKGSKGEPGLPGPPG----PMDPNLLGSKGEKGEPGL-PGIPGVSGPKGYQGLPG 988

Query: 165  QPPAGLPG--SQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRP 220
             P  G PG   QP LPG     P  +G+P + G    + PP    ++G   + G  G+  
Sbjct: 989  DP--GQPGLSGQPGLPGP----PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 221  PPN-------------------------------SLAGP----GLPAMNMGPGVRGPWAS 245
            PP                                 L GP    GLP     PG++G    
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGD 1102

Query: 246  PSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSEN--MYTIMNPIGQGAGRA 303
            P    +P    +PG+  G PG  G PGTP  P P   +    N  +     P+G G G  
Sbjct: 1103 P---GLPGLPGTPGA-KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVG-GGGHP 1157

Query: 304  NFPLGPGPEGPMAAMSAMEPHHVNG-----SLGSGDMDGLP----KSSPGAVAGLSNAPG 354
              P  PG +G         P    G       G+    GLP    +   G + G+   PG
Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG 1217

Query: 355  TPRDDGEMAAAGTFLHPFPSESYSPG 380
             P   GE        H FP     PG
Sbjct: 1218 LPGPKGEPG-----FHGFPGVQGPPG 1238



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 91/285 (31%), Positives = 104/285 (36%), Gaps = 43/285 (15%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMS--PRFPGGPRPTLRMPS- 164
            PG    +G    G   G PG+   P     P  G HG P +   P  PG P P L  P  
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP--GFHGFPGVQGPPGPPGSPGPALEGPKG 1252

Query: 165  ----QPPAGLPGSQPLLPGAMEPSPRAQGHPSM----GGPMQRVTP--PRGMASVGPQSY 214
                Q P G PG Q L PG   P P   G+  +    G P Q   P  P      GP   
Sbjct: 1253 NPGPQGPPGRPGFQGL-PGPEGP-PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310

Query: 215  GGGM-RPPPNSLAG-PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPG 272
             G   RP  N + G PGLP +   PG++GP   P        S+ P    G PG  GPPG
Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG-------SAGP---EGEPGLIGPPG 1360

Query: 273  TPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSL 330
             P +P P      S     I    G     G+      PGP+GP        P    G  
Sbjct: 1361 PPGLPGP------SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1414

Query: 331  GSGDMDGL--PKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
            G    DG    K  P    GL   PGT   DG     G    P P
Sbjct: 1415 GLPGFDGAGGRKGDP----GLPGQPGTRGLDGPPGPDGLQGPPGP 1455



 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 92/316 (29%), Positives = 113/316 (35%), Gaps = 60/316 (18%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPG--GP 156
           P P      PG     G   A   +G PG   +P  P  P  G  G+P     FPG  G 
Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP--GSKGEPGDILTFPGMKGD 559

Query: 157 RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG 216
           +  L  P  P  GLPG    LPG    +P   G P + GP      P G+   G      
Sbjct: 560 KGELGSPGAP--GLPG----LPG----TPGQDGLPGLPGPKGE---PGGITFKGE----- 601

Query: 217 GMRPPPNSLAGPGLPAMNMGP---------------GVRGPWASPSGNSIPYSSSSPGSY 261
             R PP +   PGLP  N+GP               G++G   +P    IP     PG  
Sbjct: 602 --RGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQT 658

Query: 262 TGPPGGGGPPGTP----IMPSPGDSTNSSENMYTIMNPIGQGAGRANFP-LG-PGPEGPM 315
              PG  G PG P     +  PGD     +     +  I    G    P +G PGP GP 
Sbjct: 659 ITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ---PGLPGIPGSKGEPGIPGIGLPGPPGPK 715

Query: 316 AAMSAMEPHHVNGSLGSGDMDGL--------PKSSPG-AVAGLSNAPGTPRDDGEMAAAG 366
                  P    G+ G   ++G         PK  PG A+ G    PG P   G +   G
Sbjct: 716 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG 775

Query: 367 TFLHPFPSESYSPGMT 382
                FP     PG T
Sbjct: 776 D--RGFPGPPGPPGRT 789



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 89/302 (29%), Positives = 110/302 (36%), Gaps = 63/302 (20%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM----GPHGQPFMSPRFPGGPRPTLRMP 163
            PG     G      + G PG + S  +P  P +    G  GQP + P FPG P P     
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPPGPKG 1134

Query: 164  SQPPAGLPGSQPLLPGAMEPSP-RAQGHPSMGGPM----------------QRVTP---- 202
               P G PG    LPG  EP P    GHP   GP                 Q+  P    
Sbjct: 1135 ISGPPGNPG----LPG--EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 203  -----PRGMASVGPQSYGGGMRPPPNS--LAGP-GLPAMNMGPGVRGP----------WA 244
                 P G+  +  Q   GG+   P +  L GP G P  +  PGV+GP            
Sbjct: 1189 FGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE 1248

Query: 245  SPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRAN 304
             P GN  P        + G PG  GPPG      PG+     E      NP GQ  G   
Sbjct: 1249 GPKGNPGPQGPPGRPGFQGLPGPEGPPGL-----PGNGGIKGEK----GNP-GQ-PGLPG 1297

Query: 305  FPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAA 364
             P   G +GP           +NG  G   + G+P   PG + G S  PG+   +GE   
Sbjct: 1298 LPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP-GFPG-MKGPSGVPGSAGPEGEPGL 1355

Query: 365  AG 366
             G
Sbjct: 1356 IG 1357



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 79/275 (28%), Positives = 96/275 (34%), Gaps = 47/275 (17%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQP-FMSPRFP 153
            P PV G   PG              GPPG +  P     P      G  GQP F +P  P
Sbjct: 1148 PGPVGGGGHPGQ------------PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195

Query: 154  GGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQS 213
            G P  + +       G+PG+ P LPG  +  P   G P + G      PP    S GP  
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGN-PGLPGP-KGEPGFHGFPGVQG------PPGPPGSPGPAL 1247

Query: 214  YGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG-----SYTGPPGGG 268
             G    P P     PG P     PG  GP   P    I     +PG        G  G  
Sbjct: 1248 EGPKGNPGPQ--GPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 269  GPPGTPIMPS-PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVN 327
            GPPG    P  PG            +N +    G    P  PG +GP     +  P    
Sbjct: 1306 GPPGLQGNPGRPG------------LNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1353

Query: 328  GSLGSGDMDGLPKSSPGA--VAGLSNAPGTPRDDG 360
            G +G     GLP  S  +  + G +  PG P   G
Sbjct: 1354 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG 1388



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 88/299 (29%), Positives = 106/299 (35%), Gaps = 53/299 (17%)

Query: 97   AAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPF-MSPR 151
            A P P      PG   A G      F GPPG          P     +GP+GQP  M P 
Sbjct: 754  ALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP- 812

Query: 152  FPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGP 211
             PG P   ++ P  PP G+PG  P+    +   P  +G P   G +    PP    S G 
Sbjct: 813  -PGLPGIGVQGPPGPP-GIPG--PIGQPGLHGIPGEKGDPGPPG-LDVPGPPGERGSPGI 867

Query: 212  QSYGGGMRPP-----PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPG 266
                G + PP     P      G P      G+ GP   P    IP  S  PG   G  G
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG-LKGDDG 926

Query: 267  GGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHV 326
              G PG P                    P G+  G    P  PGP GP      M+P ++
Sbjct: 927  LQGQPGLP-------------------GPTGE-KGSKGEPGLPGPPGP------MDP-NL 959

Query: 327  NGSLGSGDMDGLP----KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
             GS G     GLP     S P    GL   PG P   G+    G      P    +PG+
Sbjct: 960  LGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP-----PGPKGNPGL 1013



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 79/264 (29%), Positives = 98/264 (37%), Gaps = 41/264 (15%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQPFMSPR-------FPGGPRPTLRMPSQPPAGLPG--S 173
           +G PG +  P  P  P  GP G P   PR        PG P P      + P GLPG   
Sbjct: 50  RGFPGLEGHPGLPGFP--GPEGPP--GPRGQKGDDGIPGPPGPK---GIRGPPGLPGFPG 102

Query: 174 QPLLPG--AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPPNSLA 226
            P LPG    + +P  QG P   G       P      G Q   G     GM+  P S+ 
Sbjct: 103 TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSII 162

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMPSPGDSTN 284
              LP     PG  GP   P    +P  +  PG     GPPG  GPPG P +P P  +  
Sbjct: 163 MSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG 219

Query: 285 SSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-KSSP 343
                     P G+  G       PGP G ++     +   ++     GD  GLP    P
Sbjct: 220 -----LNFQGPKGE-KGEQGLQGPPGPPGQISE----QKRPIDVEFQKGD-QGLPGDRGP 268

Query: 344 GAVAGLSNAPGTP-RDDGEMAAAG 366
               G+   PG P  + GE    G
Sbjct: 269 PGPPGIRGPPGPPGGEKGEKGEQG 292



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 77/256 (30%), Positives = 90/256 (35%), Gaps = 29/256 (11%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPP 167
           PG     G       QGPPG    P  P A +MGP G P     FPG  R        P 
Sbjct: 364 PGLPGEKGERGFPGIQGPPGL---PGPPGAAVMGPPGPP----GFPG-ERGQKGDEGPPG 415

Query: 168 AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG-MASVGPQSYGGGMRPPPNSLA 226
             +PG     P  ++  P A G P   GP     PP   +   GP         PP S  
Sbjct: 416 ISIPG-----PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG-------PPGS-- 461

Query: 227 GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP-SPGDSTNS 285
            PG   +    GV+G       N I    S P    G PG  GPPG+   P   G+   +
Sbjct: 462 -PGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 286 SENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGA 345
                  +  I    G   FP   G  G +     M+     G LGS    GLP   PG 
Sbjct: 521 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD--KGELGSPGAPGLP-GLPG- 576

Query: 346 VAGLSNAPGTPRDDGE 361
             G    PG P   GE
Sbjct: 577 TPGQDGLPGLPGPKGE 592



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 86/308 (27%), Positives = 101/308 (32%), Gaps = 40/308 (12%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
           PG     GS+      GP G+   P  P    + GP G P   P  P GP   +  P   
Sbjct: 152 PGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP--GPIGPPGPPGLMGPPG-- 207

Query: 167 PAGLPGSQPLL------PGAMEPSPRAQGHPSMGGPMQRVTPPRGMA-SVGPQSYGGGMR 219
           P GLPG +  +      P   +     QG P   G +     P  +    G Q   G   
Sbjct: 208 PPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRG 267

Query: 220 P--PPNSLAGPGLPAMNMG-------PGVRGPWASPSGNSIPYSSSSPG--SYTGPP--- 265
           P  PP     PG P    G       PG RG       N  P     PG   Y G P   
Sbjct: 268 PPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRD 327

Query: 266 ------GGGGPPGTP--IMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG---- 313
                 G  GPPG P  ++P PG      E     +  +    G   FP   GP G    
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 314 -PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
              A M    P    G  G    +G P  S     GL   PG P   G    AG  + P 
Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP- 446

Query: 373 PSESYSPG 380
             E   PG
Sbjct: 447 SDEICEPG 454



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 86/300 (28%), Positives = 104/300 (34%), Gaps = 71/300 (23%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM-------GPHGQPFMSPR-----FPGGP 156
           GD    G       +GPPG    P  P  P M       GP G P  +       FPG P
Sbjct: 78  GDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP 137

Query: 157 R-PTLRMPSQPPAGLPGSQPLLPGA--MEPSPRAQGHPSMGGP--MQRVTPPRGM-ASVG 210
             P L+ P  PP G+PG +   PG+  M   P  +G+P   GP  +Q +  P G+   +G
Sbjct: 138 GFPGLQGPPGPP-GIPGMKG-EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIG 195

Query: 211 PQSYGGGMRPPPNSLAGPGLPAM--NMGPGVRGPWASPSGNSIPYSSSSPGSYT------ 262
           P    G M PP      PGLP    NMG   +GP        +      PG  +      
Sbjct: 196 PPGPPGLMGPP----GPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI 251

Query: 263 ---------GPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG 313
                    G PG  GPPG P +  P               P G   G       PG  G
Sbjct: 252 DVEFQKGDQGLPGDRGPPGPPGIRGP-------------PGPPGGEKGEKGEQGEPGKRG 298

Query: 314 PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                        +G  G   + GLP   PG        PG P  DGE    G    P P
Sbjct: 299 KPGK---------DGENGQPGIPGLP-GDPG-------YPGEPGRDGEKGQKGDTGPPGP 341



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 53/158 (33%), Positives = 61/158 (38%), Gaps = 12/158 (7%)

Query: 123  QGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPG--SQPLLPG 179
            QGPPG Q +P  P    M G  G P + P FPG   P+    S  P G PG    P  PG
Sbjct: 1305 QGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1363

Query: 180  AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGV 239
               PS ++       GP      P      GPQ    G +  P     PG P  N  PG 
Sbjct: 1364 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ----GPQGLPGPTGPPGDPGRNGLPGF 1419

Query: 240  RGPWASPSGNSIPYSSSSPGSYTGPPGGGG---PPGTP 274
             G         +P    + G   GPPG  G   PPG P
Sbjct: 1420 DGAGGRKGDPGLPGQPGTRG-LDGPPGPDGLQGPPGPP 1456



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/168 (30%), Positives = 59/168 (35%), Gaps = 18/168 (10%)

Query: 217 GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIM 276
           G R  P     PGLP      G  GP      + IP     P    GPPG  G PGTP +
Sbjct: 48  GERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIP-GPPGPKGIRGPPGLPGFPGTPGL 106

Query: 277 PS-PG-DSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGS 332
           P  PG D     + +       G+    G   FP   GP GP           + G  GS
Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG------MKGEPGS 160

Query: 333 GDMDGL--PKSSPG-----AVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
             M  L  PK +PG      + GL    G P   G     G    P P
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGP 208


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 98/338 (28%), Positives = 121/338 (35%), Gaps = 67/338 (19%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQP-SPHNPNAPMMGPHGQPFM----------SPRFPGGP 156
           PG+   AGS  A  F G PG      H  +  + GP G+              P    GP
Sbjct: 275 PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334

Query: 157 RPTLRMPSQP----PAGLPGSQ-----PLLPGAMEPS--PRAQGHPSMGGPMQRVTPPRG 205
                MP +     P G PG +     P  PG M P   P + G P   G      P   
Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGA 394

Query: 206 MASVGPQSYGGGMRPPPNSLAGPGLPAM---NMGPGVRGPWASPSGNSIPYSSSSPGS-- 260
               GPQ   G   PP   +  PGLP     +  PG +GP  SP  +  P S+  PGS  
Sbjct: 395 RGPEGPQGQRGETGPP-GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPG 453

Query: 261 ---YTGPPGGGGPPGTPIMPS-PGDSTNSSE-NMYTIMNPIG------------------ 297
               TGP G  G PG P +P   G++    E   + I  PIG                  
Sbjct: 454 PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG 513

Query: 298 -------QGA-GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVA 347
                  +GA G   FP   G  GP  A     P   +G  GS    G P     PGA  
Sbjct: 514 PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGA-R 572

Query: 348 GLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGMTMSV 385
           GL+  PG    +G++   G      P E   PG   S+
Sbjct: 573 GLTGNPGVQGPEGKLGPLGA-----PGEDGRPGPPGSI 605



 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 82/275 (29%), Positives = 95/275 (34%), Gaps = 48/275 (17%)

Query: 124 GPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGA--- 180
           GPPGSQ  P        GP G+P   PR P G      +P QP A  P   P  PG    
Sbjct: 135 GPPGSQ-GPRGER----GPKGRP--GPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGL 187

Query: 181 -------MEPSPRAQGHPSMGGPMQ-RVTP--PRGMASVGPQSYGGGMRPPPNSLAGPGL 230
                  M       G  S  G M   V P  PRG   +  Q  G G   PP     PG 
Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPG- 246

Query: 231 PAMNMGP----GVRGPWASPSGNSIPYSSSSPG--SYTGPPGGGGPPGTPIMPSPGDSTN 284
               MGP    G  GP   P  +  P  + +PG   + G PG  G PG P +P       
Sbjct: 247 ---PMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP----GLK 299

Query: 285 SSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----- 339
                  +  P G+  G        GP GPM AM  + P  + G  G     G P     
Sbjct: 300 GHRGHKGLEGPKGE-VGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGA 358

Query: 340 --------KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                      P  + G S  PG P   GE    G
Sbjct: 359 HGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTG 393



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 96/329 (29%), Positives = 107/329 (32%), Gaps = 46/329 (13%)

Query: 76   DRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQ--PSPH 133
            DR    E   E  A  D  A   P P+      G T   G        GPPGS+  P   
Sbjct: 778  DRGGIGEKGAEGTAGND-GARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR 836

Query: 134  NPNAPM--------MGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ--------PLL 177
              N P          GP GQP +    PG P       S  P GL GS         P L
Sbjct: 837  GENGPTGAVGFAGPQGPDGQPGVKGE-PGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGL 895

Query: 178  PG--AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAM 233
             G    +  P A G P   G   RV PP    + GP    G  G   PP     PG    
Sbjct: 896  KGGRGTQGPPGATGFPGSAG---RVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGR 952

Query: 234  NMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPG-TPIMPSPGDSTNSSENMYTI 292
                G  GP   P     P     PG   GPPG  G  G   I+  PG        M  +
Sbjct: 953  VGDRGPAGPPGGPGDKGDPGEDGQPGP-DGPPGPAGTTGQRGIVGMPGQ--RGERGMPGL 1009

Query: 293  MNPIG-------QGAGRANFPLGP-GPEGPMAAMSAMEPHHVNGSLGSGDMDGL------ 338
              P G        GA     P GP GP G    +    P    G+ G+   DG       
Sbjct: 1010 PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGD 1069

Query: 339  -PKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                 P  + G   APGTP   G    AG
Sbjct: 1070 RGDPGPAGLPGSQGAPGTPGPVGAPGDAG 1098



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 92/296 (31%), Positives = 108/296 (36%), Gaps = 35/296 (11%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNP----NAPMMGPHGQPF----MSPRFPGGPRPT 159
           PG     G   +    GP GS   P  P    NA + G  G P     + P  P GP P 
Sbjct: 602 PGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP-PG 660

Query: 160 L--RMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTP--PRGMASVGPQSYG 215
           L      Q P G  G Q L PG   P P  +G    G P  +  P  P  +  +GP+   
Sbjct: 661 LAGERGEQGPPGPTGFQGL-PGP--PGPPGEG----GKPGDQGVPGDPGAVGPLGPRGER 713

Query: 216 G--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGT 273
           G  G R  P     PG   M  G G  GP  SP  +  P  +  PG   G PG  G  GT
Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPG-LQGMPGERGIAGT 772

Query: 274 PIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG-PGPEGPMAAMSAMEPHHVNGSLGS 332
           P                T  N    GA     PLG PGP GP        P  + G  GS
Sbjct: 773 PGPKGDRGGIGEKGAEGTAGN---DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829

Query: 333 -GDMDGLPKSSP-GAVA-----GLSNAPGTPRDDGEMAAAGTFLHPFPSE-SYSPG 380
            G+     ++ P GAV      G    PG   + GE    G    P P   + SPG
Sbjct: 830 RGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG 885



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 88/311 (28%), Positives = 107/311 (34%), Gaps = 55/311 (17%)

Query: 96   AAAPSP--VMGSMAP-GDTMAAGSMAAGFFQGPPGSQ-----------PSPHNPNAPMMG 141
            A +P P  + GS  P G     G       QGPPG+            P P     P  G
Sbjct: 872  AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA-G 930

Query: 142  PHGQPFMS--PRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPM-- 197
            P G+P     P   G P    R+  + PAG PG     PG  +  P   G P   GP   
Sbjct: 931  PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG----PGD-KGDPGEDGQPGPDGPPGP 985

Query: 198  QRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWAS-----PSGNSIP 252
               T  RG+  +  Q    GM         PGLP     PG  GP  +     P G   P
Sbjct: 986  AGTTGQRGIVGMPGQRGERGM---------PGLPGPAGTPGKVGPTGATGDKGPPGPVGP 1036

Query: 253  YSSSSPGSYTGPPGGGGPPGTP----IMPSPGDSTN-------SSENMYTIMNPIGQ--G 299
              S+ P    GP G  G  GTP     +   GD  +        S+       P+G    
Sbjct: 1037 PGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD 1096

Query: 300  AGRANFPLGPGPEGP---MAAMSAMEPHHVNGSLGS-GDMDGLPKSSPGAVAGLSNAPGT 355
            AG+   P   GP GP           P    G  G  GD     +       GL   PG 
Sbjct: 1097 AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP 1156

Query: 356  PRDDGEMAAAG 366
            P  +GE  +AG
Sbjct: 1157 PGPNGEQGSAG 1167



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 79/265 (29%), Positives = 96/265 (36%), Gaps = 29/265 (10%)

Query: 124 GPPGSQPSPHNPNAP----MMGPHG-QPFMSPRFPGGPRPTLRMPSQP-PAGLPGSQPLL 177
           GP G + +P N   P    + GP G Q    P    GP+ +   P +P   GLPG++ L 
Sbjct: 516 GPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLT 575

Query: 178 PGAMEPSPRAQGHPSMGGPMQRVTP-PRGMASVGPQSYGGGMRPPPNSLAGPGLP--AMN 234
                  P  +  P +G P +   P P G   +  Q    G+  P  S   PG P  A N
Sbjct: 576 GNPGVQGPEGKLGP-LGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGN 634

Query: 235 MG-PGVRGP-----WASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSEN 288
            G PG RG         PSG   P   +      GPPG  G  G P  P P        +
Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694

Query: 289 MYTIMNPIGQGAGRANFPLGP----GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG 344
                +P   G      PLGP    G  G              G  G    DG PK SPG
Sbjct: 695 QGVPGDPGAVG------PLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG-PKGSPG 747

Query: 345 --AVAGLSNAPGTPRDDGEMAAAGT 367
                G +  PG     GE   AGT
Sbjct: 748 PSGTPGDTGPPGLQGMPGERGIAGT 772



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/189 (29%), Positives = 64/189 (33%), Gaps = 42/189 (22%)

Query: 200 VTPPRGMASVGPQSYGGG----------MRPPPNSLA---------GPGLPAMNMGP-GV 239
           VTPP     V  Q+ GGG           +  P  +          GP  P  + GP G 
Sbjct: 86  VTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGE 145

Query: 240 RGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSP-GDSTNSSENMYTIMNPIGQ 298
           RGP   P           PG   G PG  GPPG P  P P G S   S  M  +    G 
Sbjct: 146 RGPKGRPGPRGPQGIDGEPG-VPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204

Query: 299 GAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRD 358
           G+     P   GP GP        P  + G  G               AG +  PG P D
Sbjct: 205 GSQVGLMPGSVGPVGPRG------PQGLQGQQGG--------------AGPTGPPGEPGD 244

Query: 359 DGEMAAAGT 367
            G M   G+
Sbjct: 245 PGPMGPIGS 253



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/194 (31%), Positives = 65/194 (33%), Gaps = 35/194 (18%)

Query: 101  PVMGSMAPGDTMAAGSMAAGFFQGP---PGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
            P      PG   A G        GP   PGSQ +P  P     GP G P        G R
Sbjct: 1051 PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTP-----GPVGAPG-----DAGQR 1100

Query: 158  --PTLRMPSQPPA-----GLPGSQPLLPGAMEPSPRA----QGHPSMGGPMQRVTPPRGM 206
              P  R P  PP      GLPG Q       +   R     +GH    G      PP   
Sbjct: 1101 GDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPN 1160

Query: 207  ASVGPQSYGG--GMRPPPNSLAGPGLPAMNMG-PGVRGPWASPSGNSIPYSSSSPGSYTG 263
               G     G  G R PP    GP  P+   G PG  GP   P        S       G
Sbjct: 1161 GEQGSAGIPGPFGPRGPP----GPVGPSGKEGNPGPLGPIGPPGVRG----SVGEAGPEG 1212

Query: 264  PPGGGGPPGTPIMP 277
            PPG  GPPG P  P
Sbjct: 1213 PPGEPGPPGPPGPP 1226



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 55/183 (30%), Positives = 59/183 (32%), Gaps = 44/183 (24%)

Query: 95   AAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQ-----PSPHNPNAPMMGPHGQPFMS 149
            A   P PV    APGD    G   +    GPPG       P P  P     G HG     
Sbjct: 1084 APGTPGPVG---APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDK-GDHGD--RG 1137

Query: 150  PRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV 209
             R   G R           G  G Q L PG   P+   QG   + GP     PP     V
Sbjct: 1138 DRGQKGHR-----------GFTGLQGL-PGPPGPNGE-QGSAGIPGPFGPRGPP---GPV 1181

Query: 210  GPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG 269
            GP    G     P  L   G P +    G  GP               P    GPPG  G
Sbjct: 1182 GPSGKEGN----PGPLGPIGPPGVRGSVGEAGP-------------EGPPGEPGPPGPPG 1224

Query: 270  PPG 272
            PPG
Sbjct: 1225 PPG 1227


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 99/335 (29%), Positives = 118/335 (35%), Gaps = 63/335 (18%)

Query: 95   AAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM-------------- 140
            AA  P P   +  PG     G        GP G +  P  P A  +              
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 141  --GPHGQP-----FMSPRFPG--GPR--PTLRMPSQP--PAGLPGSQPLLPGAM-EPSPR 186
              GP GQP       +P  PG  GPR  P  R  + P  PAG PG+    PG   EP  +
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA----PGQNGEPGGK 824

Query: 187  ----AQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGP 242
                A G    GGP     PP G    GP     G++    S  GPG        G+ GP
Sbjct: 825  GERGAPGEKGEGGPPGVAGPPGGSGPAGPPG-PQGVKGERGSPGGPGAAGFPGARGLPGP 883

Query: 243  WASPSGNSIPYSSSSPG--SYTGPPGGGGPPGTPIMPSP-GDSTNSSENMYTIMNPIGQG 299
              S      P  S SPG     GP G  G PG+P +  P GD+    E      +P  QG
Sbjct: 884  PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK----GSPGAQG 939

Query: 300  AGRANFPLG----------PGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----KSSPGA 345
               A  PLG           GP G      +  P  V G  G    +GL        P  
Sbjct: 940  PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999

Query: 346  VAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
            + GL+   G P  DG   + G      P    SPG
Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDG-----LPGRDGSPG 1029



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 95/307 (30%), Positives = 107/307 (34%), Gaps = 60/307 (19%)

Query: 107 APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQP----FMSPRFPGGPR---- 157
           APG     G       QGPPG      +P     MGP G P     M  R P GP     
Sbjct: 364 APGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANG 423

Query: 158 -PTLRMPSQPPA-----GLPGSQ--------PLLPGAMEPS--------PRAQGHPSMGG 195
            P LR  +  P      G PG +        P +PGA            P A G P   G
Sbjct: 424 APGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG 483

Query: 196 PMQRVTP-------PRGM-ASVGPQSYGGGMRPP-PNSLAG-PGLPAMNMGPGVRGPWAS 245
             +R  P       P G+    GP    G   P  P   AG PG   +  GPG+RG   S
Sbjct: 484 --ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541

Query: 246 PSGNSIPYSSSSPGSY-----TGPPGGGGPPGTP-IMPSPGDSTNSSENMYTIMNPIGQG 299
           P G         PGS       GPPG  GP G P +M  PG   N            G+ 
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP--------GKN 593

Query: 300 AGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDD 359
             R   P GPGP+GP        P    G  G G   G   + P    GL   PGT    
Sbjct: 594 GERGG-PGGPGPQGPPGKNGETGPQGPPGPTGPGGDKG--DTGPPGPQGLQGLPGTGGPP 650

Query: 360 GEMAAAG 366
           GE    G
Sbjct: 651 GENGKPG 657



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 89/281 (31%), Positives = 104/281 (37%), Gaps = 49/281 (17%)

Query: 117 MAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPL 176
           +A G   G PG    P  P  P  G  G P  SP  PG   P    P +P    P   P 
Sbjct: 164 VAVGGLAGYPGPAGPPGPPGPP--GTSGHP-GSPGSPGYQGP----PGEPGQAGPSGPPG 216

Query: 177 LPGAMEPSPRA-----QGHPSMGGPMQRVTPP--RGMASV-------GPQSYGG-----G 217
            PGA+ PS  A      G P   G      PP  +G A +       G + + G     G
Sbjct: 217 PPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 218 MRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGS--------YTGPPGGGG 269
               P      GLP  N  PG  GP  +P     P    + G+          G PG  G
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPG 336

Query: 270 PPGTPIMP-SPGDSTNSSENMYTIMNPIGQ-GAGRANFPLG-PGPEGPMAAMSAMEPHHV 326
           PPGT   P SPG            + P G  G+  A    G PGP+G   A     P  +
Sbjct: 337 PPGTAGFPGSPGAKGE--------VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388

Query: 327 NGSL-GSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           NGS  G G+M   P   PGA  GL  A G P   G   A G
Sbjct: 389 NGSPGGKGEMG--PAGIPGA-PGLMGARGPPGPAGANGAPG 426



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 87/301 (28%), Positives = 101/301 (33%), Gaps = 37/301 (12%)

Query: 98  APSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
           AP P+    APG+    G   A   +G  G++ S   P  P  GP G    +  FPG P 
Sbjct: 295 APGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPP--GPPG----TAGFPGSPG 348

Query: 158 PTLRMPSQPPAGLPGSQPLLPGAMEPSPR----AQGHPSMGGPMQRVTPPRGMASVGPQS 213
               +    PAG PGS        EP P+    AQG P   GP      P G   +GP  
Sbjct: 349 AKGEVG---PAGSPGSNGAPGQRGEPGPQGHAGAQGPP---GPPGINGSPGGKGEMGPAG 402

Query: 214 YGG-----GMRPPPNSLAGPGLPAMNMG---PGVRGPWASPSGNSIPYSSSSPG-----S 260
             G     G R PP      G P +  G   PG  G    P        +  PG      
Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462

Query: 261 YTGPPGGGGPPGTPIMP-SPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMS 319
             G  G  G PG   +P + G+            N I    G A     PGP GP  A  
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG 522

Query: 320 AMEPHHVNGSLGSGDMDGLP-------KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
                 V G  G   M G P       K  P    G S  PG P   G     G    P 
Sbjct: 523 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582

Query: 373 P 373
           P
Sbjct: 583 P 583



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 93/323 (28%), Positives = 108/323 (33%), Gaps = 72/323 (22%)

Query: 93  YSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGS--QPSPHNPNAPM-----MGPHGQ 145
           Y   A P    G   PG +   GS  +  +QGPPG   Q  P  P  P       GP G+
Sbjct: 172 YPGPAGPPGPPGP--PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229

Query: 146 PFMSPRFPGGPRPTLRMPSQP----PAGLPGSQPL-----------------LPGAMEPS 184
              S R PG P     +P  P    PAG+PG   +                  PG    +
Sbjct: 230 DGESGR-PGRPGER-GLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 185 --PRAQGHPS----MGGPMQRVTP--PRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMN 234
             P   G P      G P +R  P  P    + G     G  G   PP      G P   
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347

Query: 235 MGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP-IMPSPGDSTNSSENMYTIM 293
              G  GP  SP  N  P     PG   G  G  GPPG P I  SPG            M
Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGP-QGHAGAQGPPGPPGINGSPGGKGE--------M 398

Query: 294 NPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-----KSSPG---- 344
            P G           PG  G M A     P   NG+ G     G P     K  PG    
Sbjct: 399 GPAGI----------PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 345 -AVAGLSNAPGTPRDDGEMAAAG 366
              AG+   PG   +DG+  + G
Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPG 471



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 94/329 (28%), Positives = 108/329 (32%), Gaps = 65/329 (19%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P P     APG     G       QGPPG             GP G P   P  PGG + 
Sbjct: 581 PGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET--------GPQGPP--GPTGPGGDKG 630

Query: 159 TLRMPS-QPPAGLPGS-----QPLLPGAMEPSPRAQ--------GHPSMGGPMQRVTPPR 204
               P  Q   GLPG+     +   PG  EP P+          G    G P +R  P  
Sbjct: 631 DTGPPGPQGLQGLPGTGGPPGENGKPG--EPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 205 --------GMASVGPQSYGGGMRPP--PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYS 254
                   G    GP+   G   PP  P +   PGL  M   PG RG   SP        
Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGM---PGERGGLGSPGPKGDKGE 745

Query: 255 SSSPGSYTGPPGGGGP--PGTPIMP-----SPGD-STNSSENMYTIMNPIGQGA------ 300
              PG+  G PG  GP  P  PI P      PGD     +  +  I  P G         
Sbjct: 746 PGGPGA-DGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG 804

Query: 301 --GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSS-------PGAVAGLSN 351
             G A FP  PG  G              G  G   + G P  S       P  V G   
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG 864

Query: 352 APGTPRDDGEMAAAGTFLHPFPSESYSPG 380
           +PG P   G   A G  L   P  + +PG
Sbjct: 865 SPGGPGAAGFPGARG--LPGPPGSNGNPG 891



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 93/344 (27%), Positives = 110/344 (31%), Gaps = 89/344 (25%)

Query: 99   PSPVMGSM-APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
            P  V G   +PG   AAG   A    GPPGS  +P  P     GP G P      P GP 
Sbjct: 856  PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP-----GPSGSPGKDG--PPGPA 908

Query: 158  PTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPM--QRVTPPRGMA-------- 207
                 P  P    P      PG  + SP AQG P   GP+    +T  RG+A        
Sbjct: 909  GNTGAPGSPGVSGPKGDAGQPGE-KGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGP 967

Query: 208  --SVGPQSYGG-----------GMRPPPN-----SLAGP-------------GLPAMNMG 236
              S GPQ   G           G R PP       LAG              GLP  +  
Sbjct: 968  RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS 1027

Query: 237  PGV---RGPWASP--------------------------SGNSIPYSSSSPGSYTGPPGG 267
            PG    RG   SP                          SG + P  +  P    G PG 
Sbjct: 1028 PGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP 1087

Query: 268  GGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVN 327
             GP         GD   + E     +       G    P  PGP G   A+ +  P    
Sbjct: 1088 QGP--------RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139

Query: 328  GSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHP 371
            G +G     G  K       G    PG   + GE  + G+  HP
Sbjct: 1140 GPVGPSGPPG--KDGTSGHPGPIGPPGPRGNRGERGSEGSPGHP 1181



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 81/292 (27%), Positives = 103/292 (35%), Gaps = 57/292 (19%)

Query: 132 PHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHP 191
           P  P AP   P+GQ    P+   GP         P  G+PG QP  PG+  P    +  P
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDP--GIPG-QPGSPGSPGPPGICESCP 145

Query: 192 SMGGPMQRVTPP-------RGMASVGPQSYGGGMRPP-----PNSLAGPGLPAMNMGPGV 239
           +  GP Q  +P         G+A  G   Y G   PP     P +   PG P     PG 
Sbjct: 146 T--GP-QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG---SPGY 199

Query: 240 RGP-----WASPSGNSIPYSSSSPGS------------------YTGPPGGGGPPGTPIM 276
           +GP      A PSG   P  +  P                      GPPG  GP G P  
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 277 PSP----GDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGS 332
           P      G    + E   T    +    G       PGP GP  A        + G+ G+
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319

Query: 333 GDMDGLPKSS----PGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
              DG   S     P    G +  PG+P   GE+  AG+     P  + +PG
Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS-----PGSNGAPG 366



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/267 (23%), Positives = 90/267 (33%), Gaps = 21/267 (7%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
            PG   + G        G PG+  +P +P  P  +GP G+     R   GP      P   
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS--GDRGESGPAGPAGAPG-- 1077

Query: 167  PAGLPGSQ-PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSL 225
            PAG  G+  P  P   +     +G   + G       P    S GP    G +  P    
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP---- 1133

Query: 226  AGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNS 285
             GP  P   +GP         SG+  P     P    G  G  G PG P  P P     +
Sbjct: 1134 -GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192

Query: 286  SENMYTIMNPIGQGAGRANFP-LGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG 344
                     P   G G A    +G    G  A     EP  ++  + + ++    KS  G
Sbjct: 1193 P-------GPCCGGVGAAAIAGIGGEKAGGFAPYYGDEP--MDFKINTDEIMTSLKSVNG 1243

Query: 345  AVAGLSNAPGTPRDDGEMAAAGTFLHP 371
             +  L +  G+ ++         F HP
Sbjct: 1244 QIESLISPDGSRKNPARNCRDLKFCHP 1270



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 44/160 (27%), Positives = 55/160 (34%), Gaps = 35/160 (21%)

Query: 84   SGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPH 143
            +G A A     +  AP P       G+T   G+      +G PG+  +P +P     GP 
Sbjct: 1070 AGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-----GPA 1124

Query: 144  GQP-FMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTP 202
            GQ   +    P GPR  +      P+G PG                GHP   GP      
Sbjct: 1125 GQQGAIGSPGPAGPRGPV-----GPSGPPGKD-----------GTSGHPGPIGP----PG 1164

Query: 203  PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGP 242
            PRG           G R    S   PG P     PG  GP
Sbjct: 1165 PRG---------NRGERGSEGSPGHPGQPGPPGPPGAPGP 1195



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 42/157 (26%), Positives = 51/157 (32%), Gaps = 44/157 (28%)

Query: 246 PSGNSIPYSSSSPGSYTGPPGGGGP------------------------PGTPIMPSP-- 279
           P G         P + T PP G GP                        PG+P  P P  
Sbjct: 80  PFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 280 -------GDSTNSSE-NMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLG 331
                  G    S + + Y + + +  G G A +P   GP GP        P   +G  G
Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVG-GLAGYPGPAGPPGPPG------PPGTSGHPG 192

Query: 332 SGDMDGL--PKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           S    G   P   PG  AG S  PG P   G    AG
Sbjct: 193 SPGSPGYQGPPGEPGQ-AGPSGPPGPPGAIGPSGPAG 228


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 91/308 (29%), Positives = 107/308 (34%), Gaps = 59/308 (19%)

Query: 103 MGSMAP-GDTMAAGSMAAGFFQGPPGS--QPSPHNPNAPM--MGPHGQPF---------- 147
           MG M P G    AG+     FQG PG   +P    P  P    GP G+P           
Sbjct: 203 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262

Query: 148 MSPRFPGGPRPTLRMPSQPPAGLPGSQ-----PLLPGAM-----------EPSPRAQGHP 191
              R P GP+     P  P  GLPG +     P L GA              SP   G P
Sbjct: 263 AGERGPPGPQGARGFPGTP--GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320

Query: 192 SMGGPM-----QRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASP 246
              GP      +  T P G A         G   PP  +   G P     PG +G  A P
Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE-AGP 379

Query: 247 SGNSIPYSSSSPGSYTGPPGGGGP------PGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300
           +G   P  +  P    G PG  GP      PGT  +P    S  +              A
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI-----------A 428

Query: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGL--PKSSPGAVAGLSNAPGTPRD 358
           G   FP   GP GP  A   + P    G  G     G   PK  PG  AG   APG   +
Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP-AGPQGAPGPAGE 487

Query: 359 DGEMAAAG 366
           +G+  A G
Sbjct: 488 EGKRGARG 495



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 93/315 (29%), Positives = 111/315 (35%), Gaps = 63/315 (20%)

Query: 96   AAAPSPVMGSMAPGD---TMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRF 152
            A AP P   S APG    T   G   A   QGPPG+   P    A  +GP G    +P  
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGA--AGRVGPPGSNG-NPGP 916

Query: 153  PGGPRPT-------LRMPSQPP--AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPP 203
            PG P P+        R  S PP  AG PG Q    G   P P  +G P   GP     PP
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ----GPAGP-PGEKGEPGDDGPSGAEGPP 971

Query: 204  --------RGMASV----GPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVRGPW 243
                    RG+  +    G + + G        G +  P +    G P     PG+ GP 
Sbjct: 972  GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031

Query: 244  ASPSGNSIPYSSSSPG-----------SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTI 292
              P     P +   PG             TG  G  G PG P  P P   T    +    
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD---- 1087

Query: 293  MNPIGQGAGRANFPLGP-GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351
                 +G   A  P+GP GP G         P    G  G     GL K   G   GL  
Sbjct: 1088 -----RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL-KGHRG-FTGLQG 1140

Query: 352  APGTPRDDGEMAAAG 366
             PG P   G+  A+G
Sbjct: 1141 LPGPPGPSGDQGASG 1155



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 77/267 (28%), Positives = 98/267 (36%), Gaps = 35/267 (13%)

Query: 124 GPPGSQPSPHNPNAP----MMGPHGQPF-MSPRFPGGPRPTLRMPSQP-PAGLPGSQPLL 177
           GPPG + +P N   P    + GP G P    P    GP+     P +P   GLPG++ L 
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563

Query: 178 --PGAMEP--------SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPP 222
             PG   P        +P   G P   GP      P  M   GP+   G     G +  P
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 623

Query: 223 NSLAGPGLPAMNMGPGVRGPW--ASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
            +    GLP  +   G  GP   A P+G      +  P  + G PG  GPPG      PG
Sbjct: 624 GAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG--GKPG 681

Query: 281 DSTNSSE-NMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP 339
           D     E     ++ P G+          PG  G   A     P  + G+ G+    G  
Sbjct: 682 DQGVPGEAGAPGLVGPRGERG-------FPGERGSPGAQGLQGPRGLPGTPGTDGPKG-- 732

Query: 340 KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
            S P    G    PG     GE  AAG
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAG 759



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 79/280 (28%), Positives = 102/280 (36%), Gaps = 41/280 (14%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPFMSPRFPG 154
           P P      PGD    G   A    GP G +  P    +P    + GP G        PG
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-------LPG 723

Query: 155 GPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG-MASVGPQS 213
            P       +  PAG PG+Q   P  ++  P  +G   + GP       RG +   GP+ 
Sbjct: 724 TPGTDGPKGASGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKG----DRGDVGEKGPEG 777

Query: 214 YGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG-- 269
             G  G R     +  PG    N   G  GP   P+G++    +      TGPPG  G  
Sbjct: 778 APGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGARGAPGERGETGPPGPAGFA 836

Query: 270 -PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNG 328
            PPG      PG      E            AG+      PGP+GP  A     P  V G
Sbjct: 837 GPPGAD--GQPGAKGEQGE------------AGQKGDAGAPGPQGPSGAPGPQGPTGVTG 882

Query: 329 SLGSGDMDGLPKSS--PGAVAGLSNAPGTPRDDGEMAAAG 366
             G+    G P ++  PGA AG    PG+  + G     G
Sbjct: 883 PKGARGAQGPPGATGFPGA-AGRVGPPGSNGNPGPPGPPG 921



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 86/297 (28%), Positives = 103/297 (34%), Gaps = 45/297 (15%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----------MMGPHGQP-FMSPR----F 152
           PG    AG        GP G Q  P  P  P          + G  G P  + PR    F
Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 153 PGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPS--------PRAQGHPSMGG-PMQR---- 199
           PG          Q P GLPG+    PG   P         P AQG P + G P +R    
Sbjct: 704 PGERGSPGAQGLQGPRGLPGT----PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 759

Query: 200 VTPPRG----MASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPY 253
           +  P+G    +   GP+   G  G R     +  PG    N   G  GP   P+G++   
Sbjct: 760 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGAR 818

Query: 254 SSSSPGSYTGPPGG---GGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGP- 309
            +      TGPPG     GPPG    P        +        P  QG   A  P GP 
Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878

Query: 310 GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G  GP  A  A  P    G  G+    G P S+     G    PG    DG   A G
Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN--PGPPGPPGPSGKDGPKGARG 933



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 96/308 (31%), Positives = 114/308 (37%), Gaps = 63/308 (20%)

Query: 98  APSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
           +P P+     PG+    G   A   +G  G QP P  P  P+ GP G     P FPG P 
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDG-QPGPAGPPGPV-GPAG----GPGFPGAPG 372

Query: 158 ------PT-LRMP--SQPPAGLPGSQPLLPGAMEPS--PRAQGHP----SMGGPMQRVTP 202
                 PT  R P  +Q P G PG+ P  PG    S  P   G P    S G P     P
Sbjct: 373 AKGEAGPTGARGPEGAQGPRGEPGT-PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 431

Query: 203 ----PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMN--MGP-GVRGPWASPSGNSIPYSS 255
               PRG    GPQ   G + P   +   PG+       GP G  GP A P G   P   
Sbjct: 432 GFPGPRGPP--GPQGATGPLGPKGQT-GEPGIAGFKGEQGPKGEPGP-AGPQGAPGPAGE 487

Query: 256 SSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA-GRANFPLGPGPEGP 314
                  G PGG GP G      PG+                +GA G   FP   G  GP
Sbjct: 488 EGKRGARGEPGGVGPIG-----PPGE----------------RGAPGNRGFPGQDGLAGP 526

Query: 315 MAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
             A     P  + G  G+    G P     PGA  GL+  PG     G++  +G      
Sbjct: 527 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA-RGLTGRPGDAGPQGKVGPSGA----- 580

Query: 373 PSESYSPG 380
           P E   PG
Sbjct: 581 PGEDGRPG 588



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 80/295 (27%), Positives = 94/295 (31%), Gaps = 41/295 (13%)

Query: 109  GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQ--------PFMSPRFPGGPRPT 159
            G   A+G       QGPPG Q  P    A  + GP G         P  +P   GG   T
Sbjct: 729  GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788

Query: 160  LRMPSQPPAGLPGSQ-------PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQ 212
              +    PAG  G +       P        +P  +G     GP     PP      G +
Sbjct: 789  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848

Query: 213  SYGG-----GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPP 265
               G     G    P      G P      GV GP  +      P ++  PG+    GPP
Sbjct: 849  GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 908

Query: 266  GGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHH 325
            G  G PG P  P P               P     GRA  P   GP GP       EP  
Sbjct: 909  GSNGNPGPPGPPGPSGKDGPKGARGDSGPP-----GRAGEPGLQGPAGPPGEKG--EP-- 959

Query: 326  VNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
              G  G    +G P   P  +AG     G P   GE    G      P  S  PG
Sbjct: 960  --GDDGPSGAEGPP--GPQGLAGQRGIVGLPGQRGERGFPG-----LPGPSGEPG 1005



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 59/177 (33%), Positives = 66/177 (37%), Gaps = 20/177 (11%)

Query: 109  GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQP-FMSPRFPGGPRPTLRMPS-QP 166
            GD    G++ A    GPPGS P P  P     G  G+     P  P GP     +   Q 
Sbjct: 1056 GDRGETGAVGAPGAPGPPGS-PGPAGPTGKQ-GDRGEAGAQGPMGPSGPAGARGIQGPQG 1113

Query: 167  PAGLPGSQPLLPGAMEPSPRA-QGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPN 223
            P G  G       A EP  R  +GH    G      PP      G     G  G R PP 
Sbjct: 1114 PRGDKGE------AGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1167

Query: 224  SLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
             +   G    N  PG  GP   P G S     + P    GPPG  GPPG P  P PG
Sbjct: 1168 PVGPSGKDGANGIPGPIGP-PGPRGRS---GETGPA---GPPGNPGPPGPPGPPGPG 1217



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 52/175 (29%), Positives = 63/175 (36%), Gaps = 14/175 (8%)

Query: 203 PRGMASVGPQSYGGGMRPPPNSL---AGPGLPAMNMGP-GVRGPWASPSGNSIPYSSSSP 258
           P  +A+   Q    G +  P  +    GP  P    GP G +GP     G+     +  P
Sbjct: 90  PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP-RGDRGDKGEKGAPGP 148

Query: 259 GSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIM-NPIGQGAGRANF-----PLGP-GP 311
               G PG  G PG P  P P        N    M     + AG A       P+GP GP
Sbjct: 149 RGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGP 208

Query: 312 EGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
            GP     A  P    G+ G     G+  S P    G    PG P DDGE    G
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGV--SGPMGPRGPPGPPGKPGDDGEAGKPG 261



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 61/223 (27%), Positives = 74/223 (33%), Gaps = 31/223 (13%)

Query: 109  GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLR------- 161
            G+    G+  A   +GPPG    P      + GP G+P      PG   P  R       
Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVGPPG-----LTGPAGEPGREGS-PGADGPPGRDGAAGVK 1055

Query: 162  --MPSQPPAGLPGSQ--PLLPGAMEPSPRA--QGHPSMGGPMQRVTPPRGMASVGPQSYG 215
                     G PG+   P  PG   P+ +   +G     GPM    P       GPQ   
Sbjct: 1056 GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ--- 1112

Query: 216  GGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGP--PGT 273
             G R        PG   +    G  G    P     P   S     +GP G  GP  P  
Sbjct: 1113 -GPRGDKGEAGEPGERGLKGHRGFTGLQGLPG----PPGPSGDQGASGPAGPSGPRGPPG 1167

Query: 274  PIMPSPGDSTNSSENMYTIMNPIGQG--AGRANFPLGPGPEGP 314
            P+ PS  D  N          P G+    G A  P  PGP GP
Sbjct: 1168 PVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1210


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 78.6 bits (192), Expect = 9e-15
 Identities = 91/308 (29%), Positives = 107/308 (34%), Gaps = 59/308 (19%)

Query: 103 MGSMAP-GDTMAAGSMAAGFFQGPPGS--QPSPHNPNAPM--MGPHGQPF---------- 147
           MG M P G    AG+     FQG PG   +P    P  P    GP G+P           
Sbjct: 134 MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 193

Query: 148 MSPRFPGGPRPTLRMPSQPPAGLPGSQ-----PLLPGAM-----------EPSPRAQGHP 191
              R P GP+     P  P  GLPG +     P L GA              SP   G P
Sbjct: 194 AGERGPPGPQGARGFPGTP--GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 251

Query: 192 SMGGPM-----QRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASP 246
              GP      +  T P G A         G   PP  +   G P     PG +G  A P
Sbjct: 252 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE-AGP 310

Query: 247 SGNSIPYSSSSPGSYTGPPGGGGP------PGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300
           +G   P  +  P    G PG  GP      PGT  +P    S  +              A
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI-----------A 359

Query: 301 GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGL--PKSSPGAVAGLSNAPGTPRD 358
           G   FP   GP GP  A   + P    G  G     G   PK  PG  AG   APG   +
Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP-AGPQGAPGPAGE 418

Query: 359 DGEMAAAG 366
           +G+  A G
Sbjct: 419 EGKRGARG 426



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 93/315 (29%), Positives = 111/315 (35%), Gaps = 63/315 (20%)

Query: 96   AAAPSPVMGSMAPGD---TMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRF 152
            A AP P   S APG    T   G   A   QGPPG+   P    A  +GP G    +P  
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP--GAAGRVGPPGSN-GNPGP 847

Query: 153  PGGPRPT-------LRMPSQPP--AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPP 203
            PG P P+        R  S PP  AG PG    L G   P P  +G P   GP     PP
Sbjct: 848  PGPPGPSGKDGPKGARGDSGPPGRAGEPG----LQGPAGP-PGEKGEPGDDGPSGAEGPP 902

Query: 204  --------RGMASV----GPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVRGPW 243
                    RG+  +    G + + G        G +  P +    G P     PG+ GP 
Sbjct: 903  GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962

Query: 244  ASPSGNSIPYSSSSPG-----------SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTI 292
              P     P +   PG             TG  G  G PG P  P P   T    +    
Sbjct: 963  GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD---- 1018

Query: 293  MNPIGQGAGRANFPLGP-GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSN 351
                 +G   A  P+GP GP G         P    G  G     GL K   G   GL  
Sbjct: 1019 -----RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL-KGHRG-FTGLQG 1071

Query: 352  APGTPRDDGEMAAAG 366
             PG P   G+  A+G
Sbjct: 1072 LPGPPGPSGDQGASG 1086



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 77/267 (28%), Positives = 98/267 (36%), Gaps = 35/267 (13%)

Query: 124 GPPGSQPSPHNPNAP----MMGPHGQPF-MSPRFPGGPRPTLRMPSQP-PAGLPGSQPLL 177
           GPPG + +P N   P    + GP G P    P    GP+     P +P   GLPG++ L 
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494

Query: 178 --PGAMEP--------SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPP 222
             PG   P        +P   G P   GP      P  M   GP+   G     G +  P
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLP 554

Query: 223 NSLAGPGLPAMNMGPGVRGPW--ASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
            +    GLP  +   G  GP   A P+G      +  P  + G PG  GPPG      PG
Sbjct: 555 GAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG--GKPG 612

Query: 281 DSTNSSE-NMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP 339
           D     E     ++ P G+          PG  G   A     P  + G+ G+    G  
Sbjct: 613 DQGVPGEAGAPGLVGPRGERG-------FPGERGSPGAQGLQGPRGLPGTPGTDGPKG-- 663

Query: 340 KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
            S P    G    PG     GE  AAG
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAG 690



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 79/280 (28%), Positives = 102/280 (36%), Gaps = 41/280 (14%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPFMSPRFPG 154
           P P      PGD    G   A    GP G +  P    +P    + GP G        PG
Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-------LPG 654

Query: 155 GPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG-MASVGPQS 213
            P       +  PAG PG+Q   P  ++  P  +G   + GP       RG +   GP+ 
Sbjct: 655 TPGTDGPKGASGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKG----DRGDVGEKGPEG 708

Query: 214 YGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG-- 269
             G  G R     +  PG    N   G  GP   P+G++    +      TGPPG  G  
Sbjct: 709 APGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGARGAPGERGETGPPGPAGFA 767

Query: 270 -PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNG 328
            PPG      PG      E            AG+      PGP+GP  A     P  V G
Sbjct: 768 GPPGAD--GQPGAKGEQGE------------AGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813

Query: 329 SLGSGDMDGLPKSS--PGAVAGLSNAPGTPRDDGEMAAAG 366
             G+    G P ++  PGA AG    PG+  + G     G
Sbjct: 814 PKGARGAQGPPGATGFPGA-AGRVGPPGSNGNPGPPGPPG 852



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 86/297 (28%), Positives = 103/297 (34%), Gaps = 45/297 (15%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----------MMGPHGQP-FMSPR----F 152
           PG    AG        GP G Q  P  P  P          + G  G P  + PR    F
Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 153 PGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPS--------PRAQGHPSMGG-PMQR---- 199
           PG          Q P GLPG+    PG   P         P AQG P + G P +R    
Sbjct: 635 PGERGSPGAQGLQGPRGLPGT----PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 690

Query: 200 VTPPRG----MASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPY 253
           +  P+G    +   GP+   G  G R     +  PG    N   G  GP   P+G++   
Sbjct: 691 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-PGPAGSAGAR 749

Query: 254 SSSSPGSYTGPPGG---GGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGP- 309
            +      TGPPG     GPPG    P        +        P  QG   A  P GP 
Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809

Query: 310 GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G  GP  A  A  P    G  G+    G P S+     G    PG    DG   A G
Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN--PGPPGPPGPSGKDGPKGARG 864



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 96/308 (31%), Positives = 114/308 (37%), Gaps = 63/308 (20%)

Query: 98  APSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
           +P P+     PG+    G   A   +G  G QP P  P  P+ GP G     P FPG P 
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDG-QPGPAGPPGPV-GPAG----GPGFPGAPG 303

Query: 158 ------PT-LRMP--SQPPAGLPGSQPLLPGAMEPS--PRAQGHP----SMGGPMQRVTP 202
                 PT  R P  +Q P G PG+ P  PG    S  P   G P    S G P     P
Sbjct: 304 AKGEAGPTGARGPEGAQGPRGEPGT-PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP 362

Query: 203 ----PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMN--MGP-GVRGPWASPSGNSIPYSS 255
               PRG    GPQ   G + P   +   PG+       GP G  GP A P G   P   
Sbjct: 363 GFPGPRGPP--GPQGATGPLGPKGQT-GEPGIAGFKGEQGPKGEPGP-AGPQGAPGPAGE 418

Query: 256 SSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA-GRANFPLGPGPEGP 314
                  G PGG GP G      PG+                +GA G   FP   G  GP
Sbjct: 419 EGKRGARGEPGGVGPIG-----PPGE----------------RGAPGNRGFPGQDGLAGP 457

Query: 315 MAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPF 372
             A     P  + G  G+    G P     PGA  GL+  PG     G++  +G      
Sbjct: 458 KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA-RGLTGRPGDAGPQGKVGPSGA----- 511

Query: 373 PSESYSPG 380
           P E   PG
Sbjct: 512 PGEDGRPG 519



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 80/295 (27%), Positives = 94/295 (31%), Gaps = 41/295 (13%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQ--------PFMSPRFPGGPRPT 159
           G   A+G       QGPPG Q  P    A  + GP G         P  +P   GG   T
Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719

Query: 160 LRMPSQPPAGLPGSQ-------PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQ 212
             +    PAG  G +       P        +P  +G     GP     PP      G +
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779

Query: 213 SYGG-----GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPP 265
              G     G    P      G P      GV GP  +      P ++  PG+    GPP
Sbjct: 780 GEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP 839

Query: 266 GGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHH 325
           G  G PG P  P P               P     GRA  P   GP GP       EP  
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGPP-----GRAGEPGLQGPAGPPGEKG--EP-- 890

Query: 326 VNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
             G  G    +G P   P  +AG     G P   GE    G      P  S  PG
Sbjct: 891 --GDDGPSGAEGPP--GPQGLAGQRGIVGLPGQRGERGFPG-----LPGPSGEPG 936



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 59/177 (33%), Positives = 66/177 (37%), Gaps = 20/177 (11%)

Query: 109  GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQP-FMSPRFPGGPRPTLRMPS-QP 166
            GD    G++ A    GPPGS P P  P     G  G+     P  P GP     +   Q 
Sbjct: 987  GDRGETGAVGAPGAPGPPGS-PGPAGPTGKQ-GDRGEAGAQGPMGPSGPAGARGIQGPQG 1044

Query: 167  PAGLPGSQPLLPGAMEPSPRA-QGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPN 223
            P G  G       A EP  R  +GH    G      PP      G     G  G R PP 
Sbjct: 1045 PRGDKGE------AGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1098

Query: 224  SLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
             +   G    N  PG  GP   P G S     + P    GPPG  GPPG P  P PG
Sbjct: 1099 PVGPSGKDGANGIPGPIGP-PGPRGRS---GETGPA---GPPGNPGPPGPPGPPGPG 1148



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 47/150 (31%), Positives = 55/150 (36%), Gaps = 11/150 (7%)

Query: 225 LAGPGLPAMNMGP-GVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDST 283
           + GP  P    GP G +GP     G+     +  P    G PG  G PG P  P P    
Sbjct: 46  IVGPKGPPGPQGPAGEQGP-RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPP 104

Query: 284 NSSENMYTIM-NPIGQGAGRANF-----PLGP-GPEGPMAAMSAMEPHHVNGSLGSGDMD 336
               N    M     + AG A       P+GP GP GP     A  P    G+ G     
Sbjct: 105 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 164

Query: 337 GLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G+  S P    G    PG P DDGE    G
Sbjct: 165 GV--SGPMGPRGPPGPPGKPGDDGEAGKPG 192



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 61/223 (27%), Positives = 74/223 (33%), Gaps = 31/223 (13%)

Query: 109  GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLR------- 161
            G+    G+  A   +GPPG    P      + GP G+P      PG   P  R       
Sbjct: 933  GEPGKQGAPGASGDRGPPGPVGPPG-----LTGPAGEPGREGS-PGADGPPGRDGAAGVK 986

Query: 162  --MPSQPPAGLPGSQ--PLLPGAMEPSPRA--QGHPSMGGPMQRVTPPRGMASVGPQSYG 215
                     G PG+   P  PG   P+ +   +G     GPM    P       GPQ   
Sbjct: 987  GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ--- 1043

Query: 216  GGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGP--PGT 273
             G R        PG   +    G  G    P     P   S     +GP G  GP  P  
Sbjct: 1044 -GPRGDKGEAGEPGERGLKGHRGFTGLQGLPG----PPGPSGDQGASGPAGPSGPRGPPG 1098

Query: 274  PIMPSPGDSTNSSENMYTIMNPIGQG--AGRANFPLGPGPEGP 314
            P+ PS  D  N          P G+    G A  P  PGP GP
Sbjct: 1099 PVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1141



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 70/271 (25%), Positives = 85/271 (31%), Gaps = 61/271 (22%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQP-----FMSPRFPGGPRPTLRMPSQPPAGLPGSQPLL 177
           QG    QP P        G  G+P      + P+ P GP        Q PAG        
Sbjct: 24  QGQDVRQPGPK-------GQKGEPGDIKDIVGPKGPPGP--------QGPAG-------- 60

Query: 178 PGAMEPSPRA----QGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAM 233
               E  PR     +G     GP  R   P    + GP         PP     PGL   
Sbjct: 61  ----EQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPG-------PPGPPGPPGLGG- 108

Query: 234 NMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP----IMPSPGDSTNSSENM 289
           N    + G +   +G +       P    GP G  GP G P       +PG+        
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG--- 165

Query: 290 YTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGL 349
             +  P+G   G    P  PG +G              G  G+    G P   PG V G 
Sbjct: 166 --VSGPMGP-RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP-GLPG-VKGH 220

Query: 350 SNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
              PG     GE  A G        ES SPG
Sbjct: 221 RGYPGLDGAKGEAGAPGV-----KGESGSPG 246


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 103/346 (29%), Positives = 117/346 (33%), Gaps = 70/346 (20%)

Query: 93   YSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQ--PSPHNPNAPM--MGPHG---- 144
            Y  A  P  + G    G+    GS       GPPGS+  P P  P  P    GP G    
Sbjct: 1091 YPGATGPPGLPG--IKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGE 1148

Query: 145  ---QPFMS-PRFPGGPRPT-----LRMPSQP-------------PAGLPGSQPLLPGAME 182
               Q F   P FPG P P      +  P  P             P+GLPGS    PG   
Sbjct: 1149 KGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGS----PGPPG 1204

Query: 183  PSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPP--PNSLAGPGLPAMNMGPGVR 240
            P P  QG   + G   +   P      GP    G M PP        PGLP      G  
Sbjct: 1205 P-PGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKP 1263

Query: 241  GPWASPSGNSIPYSSSSPGSY-----TGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNP 295
            GP   P     P +   PG+       GPPG  GPPG P  P P     S+  +      
Sbjct: 1264 GP---PGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGI--SAVGLKGDRGA 1318

Query: 296  IGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGL-----PKSSPGAVA--- 347
             G+  G A  P  PGP G              G  G     G      PK  PGA     
Sbjct: 1319 TGE-RGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKG 1377

Query: 348  -----GLSNAPGTPRDDGEM------AAAGTFLHP-FPSESYSPGM 381
                 G +  PG P   G M        AG   HP  P  S SPG+
Sbjct: 1378 QAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGL 1423



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 83/293 (28%), Positives = 99/293 (33%), Gaps = 71/293 (24%)

Query: 124  GPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQP-PAGLP---------- 171
            GPPGS   P     P  MGP G+P   P   G P P    P QP PAG+           
Sbjct: 1264 GPPGSTGRPGAEGEPGAMGPQGRPG-PPGHVGPPGP----PGQPGPAGISAVGLKGDRGA 1318

Query: 172  -GSQPL--LPGAMEPS--PRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLA 226
             G + L  LPG   P   P   G P   G   +  PP      G Q + G    PP    
Sbjct: 1319 TGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPP------GKQGFYG----PPGPKG 1368

Query: 227  GPGLPAMNMGPGVRGPWASP-----SGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP---- 277
             PG        G +G    P     SG+  P     P    G PG  GP G+P +P    
Sbjct: 1369 DPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPG 1428

Query: 278  SPGDSTNSSENMYTIMNPI--------GQGAGRANFPL----------GPGPEGPMAAMS 319
            S GD  N  E    I   I             R  FP+           PG +G      
Sbjct: 1429 SMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG 1488

Query: 320  AMEPHHVNGSLGSGDMDGLP--KSSPG----------AVAGLSNAPGTPRDDG 360
            A     + G +G     GLP  +  PG           +AG +  PG P   G
Sbjct: 1489 APGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQG 1541



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 84/291 (28%), Positives = 109/291 (37%), Gaps = 58/291 (19%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSP----RFPGGPR------ 157
           PG    AG       +G  G   +P +P  P  G  G+P +S     + P GP+      
Sbjct: 669 PGKQGKAGERG---LKGQKGDAGNPGDPGTP--GTTGRPGLSGEPGVQGPAGPKGEKGDG 723

Query: 158 ----PTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGP--MQRVTPPRGMASVG- 210
               P+L+      AG PG QP   G  E  P   G P   G   +  V  P G+  V  
Sbjct: 724 CTACPSLQGTVTDMAGRPG-QPGPKG--EQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQG 780

Query: 211 -PQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPG-----SYTGP 264
            P   G G++ P      PGLP +   PG RGP   P+G     +  SPG        GP
Sbjct: 781 EPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP-PGPTGEK--GAQGSPGVKGATGPVGP 837

Query: 265 PGG--GGPPG-------TPIMPSPGD-------------STNSSENMYTIMNPIGQGAGR 302
           PG    GPPG       T +  +PG+             S  S  ++     P   G   
Sbjct: 838 PGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWM 897

Query: 303 ANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAP 353
            +    PGP+GP        P  V G  G    +GLP   PG  A L + P
Sbjct: 898 GS-SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLP-GQPGLTAELGSLP 946



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 52/189 (27%), Positives = 63/189 (33%), Gaps = 24/189 (12%)

Query: 184  SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPP--PNSLAGPGLPAMNMGPGVRG 241
            SP   G P + G      PP    S GP    G + PP  P ++  PGLP +    G RG
Sbjct: 1019 SPGLPGPPGLPGQRGEEGPPGMRGSPGPP---GPIGPPGFPGAVGSPGLPGLQ---GERG 1072

Query: 242  PWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAG 301
                      P     PG     PG  GPPG P +      T S+        P  +G  
Sbjct: 1073 LTGLTGDKGEPGPPGQPGY----PGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGL- 1127

Query: 302  RANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----KSSPGAVAGLSNAPGTPR 357
                   PGP GP        P   +G  G     G P       P    G   +PG P 
Sbjct: 1128 -------PGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180

Query: 358  DDGEMAAAG 366
               E  + G
Sbjct: 1181 PQAEKGSEG 1189



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 82/331 (24%), Positives = 114/331 (34%), Gaps = 52/331 (15%)

Query: 87  AKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQ----GPPGSQPSPH--------- 133
           AK  Q+ +A   P  V G+     T+A      G  +    GPPGS+             
Sbjct: 305 AKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRI 364

Query: 134 NPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLL-------PGAMEPSPR 186
           +P+AP+    G     P+   G    L      P+GLPGS            G ++  P 
Sbjct: 365 SPDAPLQCAEG-----PKGEKGESGALG-----PSGLPGSTGEKGQKGEKGDGGIKGVPG 414

Query: 187 AQGHPSMGGPMQRVTPPRGMAS----VGPQSYGGGMRPPPNSLAGP---GLPAMNMGPG- 238
             G     G +  V  P+G       VGP+   G   P P  L GP   GLP     PG 
Sbjct: 415 KPGRDGRPGEIC-VIGPKGQKGDPGFVGPEGLAG--EPGPPGLPGPPGIGLPGTPGDPGG 471

Query: 239 VRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP--IMPSPGDSTNSSENMYTIMNPI 296
             GP      + IP     PG   G PG  G  G P  + P+  +   +   +     P 
Sbjct: 472 PPGPKGDKGSSGIP-GKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPK 530

Query: 297 GQGAGRANFPLGPGPEGP--------MAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAG 348
           G+          PG +G         ++  S +   H+  S G+    G P      + G
Sbjct: 531 GEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPG 590

Query: 349 LSNAPGTPRDDGEMAAAGTFLHPFPSESYSP 379
            +  PG   + G    AG    P P     P
Sbjct: 591 RAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP 621



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 82/286 (28%), Positives = 91/286 (31%), Gaps = 51/286 (17%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLP---G 179
            QGPPG    P  P  P  G  G P  +   PG P  T  + S     LP  Q LL    G
Sbjct: 906  QGPPGIPGPPGPPGVP--GLQGVPGNNG-LPGQPGLTAELGS-----LPIEQHLLKSICG 957

Query: 180  AMEPSPRA-------------QGHPSMGGP------MQRVTPPRGMASVGPQSYGGGMRP 220
                  RA             QG P + G          +  PR   + G  S G     
Sbjct: 958  DCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGD---- 1013

Query: 221  PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP-IMPSP 279
             P  +  PGLP     PG RG    P     P          GPPG  GPPG P  + SP
Sbjct: 1014 -PGCVGSPGLPGPPGLPGQRGEEGPPGMRGSP----------GPPGPIGPPGFPGAVGSP 1062

Query: 280  GDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP 339
            G      E   T +       G    P  PG  GP             GS G     G P
Sbjct: 1063 GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPP 1122

Query: 340  KS----SPGAVAGLSNAPGTPRDDGEMAAAGTFLHP-FPSESYSPG 380
             S     P   AG     G   + GE    G    P FP     PG
Sbjct: 1123 GSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 69/268 (25%), Positives = 93/268 (34%), Gaps = 38/268 (14%)

Query: 124 GPPGSQPSPHNPNAP-MMGPHGQPF-MSPRFPGGPRPTLRMPSQP-PAGLPGSQPLLPGA 180
           G PG +     P  P + G  G P  + P  P G +  + +P +P P G PG    +P  
Sbjct: 483 GIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDP--VPAR 540

Query: 181 MEPSPRA----QGHP-----SMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLP 231
            +P  +     +G P     S+ G    V+       VG   +G            PGLP
Sbjct: 541 GDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGL-----------PGLP 589

Query: 232 AMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYT 291
                PG++G   +  G + P  S  P    GP G  G  G P  P P  S     ++  
Sbjct: 590 GRAGVPGLKGEKGN-FGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRV 648

Query: 292 IMNPIGQGAGRANFPLG---PGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA- 347
           +  P   G      P G   PG +G            + G  G     G P  +PG    
Sbjct: 649 VALPGPSGEKGEPGPPGFGLPGKQGKAGERG------LKGQKGDAGNPGDP-GTPGTTGR 701

Query: 348 -GLSNAPGTPRDDGEMAAAGTFLHPFPS 374
            GLS  PG     G     G      PS
Sbjct: 702 PGLSGEPGVQGPAGPKGEKGDGCTACPS 729



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 81/312 (25%), Positives = 99/312 (31%), Gaps = 84/312 (26%)

Query: 123  QGPPGS---QPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPG 179
            QGPPG    Q  P  P   + GP G+P       G P            GLPG Q L   
Sbjct: 770  QGPPGLKGVQGEPGPPGRGVQGPQGEP-------GAP------------GLPGIQGLPGP 810

Query: 180  AMEPSPR----AQGHPSMGGPMQRVTPPRGMASVGPQSYGG-----GMRPPPNSLAG--- 227
               P P     AQG P + G    V PP G +  GP    G     G+R  P        
Sbjct: 811  RGPPGPTGEKGAQGSPGVKGATGPVGPP-GASVSGPPGRDGQQGQTGLRGTPGEKGPRGE 869

Query: 228  --------------------PGLPAMNMG----PGVRGPWASPSGNSIPYSSSSPGSYTG 263
                                PG P + MG    PG +GP   P     P     PG   G
Sbjct: 870  KGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPP---GVPG-LQG 925

Query: 264  PPGGGGPPGTPIMPSPGDSTNSSENMY-TIMNPIGQG-------------AGRANFPLGP 309
             PG  G PG P + +   S    +++  +I     QG              G    P  P
Sbjct: 926  VPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVP 985

Query: 310  GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA--GLSNAPGTPRDDGEMAAAGT 367
            G +       ++E      + G        +  PG V   GL   PG P   GE    G 
Sbjct: 986  GLDNCAQCFLSLERPRAEEARGDNS-----EGDPGCVGSPGLPGPPGLPGQRGEEGPPGM 1040

Query: 368  FLHPFPSESYSP 379
               P P     P
Sbjct: 1041 RGSPGPPGPIGP 1052



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 75/255 (29%), Positives = 86/255 (33%), Gaps = 69/255 (27%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQ-----PSPH-NPNAPMMGPHGQPFMSPR--FPGGPRPT 159
            PG     G+  A   +GPPG Q     P P  +P A   G  GQ     R   PGGP  +
Sbjct: 1337 PGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAA--GQKGQAGEKGRAGMPGGPGKS 1394

Query: 160  LRMPSQPPAGLPGSQPLLPGAMEPS--PRAQGHPSMGGPM-------------------- 197
              M    P G P  +   PGA  PS  P   G P   G M                    
Sbjct: 1395 GSMGPVGPPG-PAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDE 1453

Query: 198  ------QRVTPPRGMASV----GPQSYGGGMRPPPNSLAGPGLPAM-----NMG-PGVRG 241
                   R+  P  MA+     GP    G    P  +   PGLP         G PGVRG
Sbjct: 1454 RMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRP-GAPGSPGLPGQIGREGRQGLPGVRG 1512

Query: 242  -PWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA 300
             P        I    +      GPPG  GPPG   M + G              P+GQ  
Sbjct: 1513 LPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATG--------------PMGQ-- 1556

Query: 301  GRANFPLGPGPEGPM 315
                 P  PGP GPM
Sbjct: 1557 --QGIPGIPGPPGPM 1569



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 54/204 (26%), Positives = 70/204 (34%), Gaps = 33/204 (16%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGP----------- 156
            PG    +GSM      GPPG      +P AP  GP G P + P  PG             
Sbjct: 1388 PGGPGKSGSMGP---VGPPGPAGERGHPGAP--GPSGSPGL-PGVPGSMGDMVNYDEIKR 1441

Query: 157  ---RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQS 213
               +  ++M  +  A    S+   P  M  +P   G P   G   R   P      G   
Sbjct: 1442 FIRQEIIKMFDERMAYYT-SRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIG 1500

Query: 214  YGG-----GMRPPPNSLA-----GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTG 263
              G     G+R  P +       G G+   N  PG  GP   P    +   ++ P    G
Sbjct: 1501 REGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKM--GATGPMGQQG 1558

Query: 264  PPGGGGPPGTPIMPSPGDSTNSSE 287
             PG  GPPG    P      N S+
Sbjct: 1559 IPGIPGPPGPMGQPGKAGHCNPSD 1582


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 80/256 (31%), Positives = 92/256 (35%), Gaps = 34/256 (13%)

Query: 106 MAPGDTMAAGSMAAGFFQGPPGS----QPSPHNPNAPMMGPHGQPFMSPRFPGGP-RPTL 160
           + P   +  G +A GF  G PG     Q  P  P  PM GPHG        PGGP  P L
Sbjct: 614 LVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGG-------PGGPVGPRL 666

Query: 161 RMPSQPPAG------LPGSQPLLPGAME------PSPRAQGHPSMGGPMQRVTPPRGMAS 208
             P  PP G       PG  P+  G M       P P  +G    GG      PP    +
Sbjct: 667 LGPPPPPRGGDPFWDGPG-DPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGA 725

Query: 209 VGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGG 268
            G +S GG    PPN   GPG     +G G   P   P G     +SS    + GP GG 
Sbjct: 726 RGGRSGGG----PPNGRGGPG--GGMVGGGGHRPHEGPGGGM--GNSSGHRPHEGPGGGM 777

Query: 269 GPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNG 328
           G    P    PG S            P G  +G +      GP G M A     PH   G
Sbjct: 778 GSGHRP-HEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPG 836

Query: 329 SLGSGDMDGLPKSSPG 344
               G     P   PG
Sbjct: 837 GSMGGSGGHRPHEGPG 852



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/248 (29%), Positives = 85/248 (34%), Gaps = 36/248 (14%)

Query: 115 GSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174
           GSM AG  +GP G      N    +    G P           P+  +  QP       Q
Sbjct: 563 GSMGAG--KGPQGPGGGGINVQEILTSIMGSP--------NSHPSEELLKQPDYSDKIKQ 612

Query: 175 PLLP-GAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAM 233
            L+P G + P P A G P  GGP      P+GM    P   G    P P    GPG P  
Sbjct: 613 MLVPHGLLGPGPIANGFPP-GGP----GGPKGMQHFPPGPGG----PMPGPHGGPGGP-- 661

Query: 234 NMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSE--NMYT 291
            +GP + GP   P G    +         GP  GG  PG    P P          N   
Sbjct: 662 -VGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG----PGPYHRGRGGRGGNEPP 716

Query: 292 IMNPIGQGAGRANFPLGP-----GPEGPMAAMSAMEPHHVNGSLGSGDMDG-LPKSSPGA 345
              P  +GA       GP     GP G M       PH   G  G G+  G  P   PG 
Sbjct: 717 PPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG-GMGNSSGHRPHEGPGG 775

Query: 346 VAGLSNAP 353
             G  + P
Sbjct: 776 GMGSGHRP 783



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 7/72 (9%)

Query: 122 FQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAM 181
           F+G   ++PS   P++P   P  +   + R PG P P + +P      L  +  L PGA+
Sbjct: 322 FEGKTSTEPSTAKPSSPEPAPPSEAMDADR-PGTPVPPVEVPE-----LMDTASLEPGAL 375

Query: 182 EPSP-RAQGHPS 192
           +  P  + G P+
Sbjct: 376 DAKPVESPGDPN 387


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 86/298 (28%), Positives = 112/298 (37%), Gaps = 48/298 (16%)

Query: 82  EHSGEAKAFQDYSAAAAPSPVMGSMA---PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP 138
           ++  E      Y     P+P MG  A    G  +   S+     QGP G +P P  P  P
Sbjct: 78  QYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGE--QGPRG-EPGPRGPPGP 134

Query: 139 MMGPHGQPFMSPRFPGGPRPTLRMPSQP-PAGLPG-SQPLLPGAMEPSPRAQGHPSMGGP 196
                      P  PG   P ++   +P P G PG  +P +PG M   P A G P   G 
Sbjct: 135 -----------PGLPGHGIPGIK--GKPGPQGYPGVGKPGMPG-MPGKPGAMGMPGAKGE 180

Query: 197 MQRVTPPRGMASVGPQSYGGGMRPP-PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSS 255
           + +         +GP    G   PP P+ L G G P    GPG+ G    P G+  P   
Sbjct: 181 IGQ------KGEIGPMGIPGPQGPPGPHGLPGIGKPG---GPGLPGQ-PGPKGDRGPKGL 230

Query: 256 SSPGSYTGPPG--GGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGAGRANFPLGPGPE 312
             P    GP G  G G PG P +  P         M+    P+G  G G+      PGP+
Sbjct: 231 PGPQGLRGPKGDKGFGMPGAPGVKGP-------PGMHGPPGPVGLPGVGKPGVTGFPGPQ 283

Query: 313 GPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG----AVAGLSNAPGTPRDDGEMAAAG 366
           GP+    A       G +G   + G P   PG       G+   PG P   GE    G
Sbjct: 284 GPLGKPGAPGEPGPQGPIGVPGVQG-PPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPG 340



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 89/307 (28%), Positives = 106/307 (34%), Gaps = 53/307 (17%)

Query: 107 APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFM--SPRFPGGPRPTLRMPS 164
           APG+    G +     QGPPG          P +G  GQ  +   P FPGG +    +P 
Sbjct: 291 APGEPGPQGPIGVPGVQGPPG---------IPGIGKPGQDGIPGQPGFPGG-KGEQGLPG 340

Query: 165 QP-PAGLPG-SQPLLPGAMEP----------SPRAQ----GHPSMGGPMQR--------- 199
            P P GLPG  +P  PG               PR +    G P +GGP            
Sbjct: 341 LPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP 400

Query: 200 VTPPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSS 257
           + PP  +   GP+  GG  G + PP     PGL      PG  G    P    +P     
Sbjct: 401 MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP-GPIG 459

Query: 258 PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA-GRANFPLGPGPEGPMA 316
           P    G  G  G PG P +  P               P  QG  G    P   GP GP+ 
Sbjct: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGI---------PGDQGLQGPPGIPGIGGPSGPIG 510

Query: 317 AMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSES 376
                 P    G  G     G+ K  PG VAGL   PG P   G     G    P P   
Sbjct: 511 PPGIPGPKGEPGLPGPPGFPGIGK--PG-VAGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567

Query: 377 YSPGMTM 383
             P   M
Sbjct: 568 PGPPAVM 574



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 84/284 (29%), Positives = 109/284 (38%), Gaps = 43/284 (15%)

Query: 122 FQGPPGSQPSPHNPNAPMMGPHGQ--PFMSPRFPGGPR----PTLRMPSQPPA--GLPGS 173
           F GP G +     P A  +GP G+  P  +P   G P     P +  P  PP   G PG 
Sbjct: 355 FPGPKGDRGMGGVPGA--LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412

Query: 174 Q-------PLLPGAMEPSPRAQGHPSMGGPMQRVTPP--RGMAS-VGPQSYGGGMRPPPN 223
           +       P  P   +  P  QG P   G +  V PP  RG+   +GP+   G  +  P 
Sbjct: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAG-QKGVPG 471

Query: 224 SLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS-PGDS 282
               PGL      PG+ G         IP     P    GPPG  GP G P +P  PG  
Sbjct: 472 LPGVPGLLGPKGEPGIPGDQGLQGPPGIP-GIGGPSGPIGPPGIPGPKGEPGLPGPPGFP 530

Query: 283 TNSSENMYTIMNPIGQ-GA----GRANFPLGPGPEGPMAAMSAMEP-----HHVNGSLGS 332
                 +  +  P G+ GA    G+   P  PGP GP    + M P           +G 
Sbjct: 531 GIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGL 590

Query: 333 GDMDGL-PKSSPGAVAGLSNAPG--TPRDDGEMAAAGTFLHPFP 373
           G +DG+ P  + GA  G +  P    P    E+ A      PFP
Sbjct: 591 G-IDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTA------PFP 627


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 86/298 (28%), Positives = 112/298 (37%), Gaps = 48/298 (16%)

Query: 82  EHSGEAKAFQDYSAAAAPSPVMGSMA---PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP 138
           ++  E      Y     P+P MG  A    G  +   S+     QGP G +P P  P  P
Sbjct: 78  QYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGE--QGPRG-EPGPRGPPGP 134

Query: 139 MMGPHGQPFMSPRFPGGPRPTLRMPSQP-PAGLPG-SQPLLPGAMEPSPRAQGHPSMGGP 196
                      P  PG   P ++   +P P G PG  +P +PG M   P A G P   G 
Sbjct: 135 -----------PGLPGHGIPGIK--GKPGPQGYPGVGKPGMPG-MPGKPGAMGMPGAKGE 180

Query: 197 MQRVTPPRGMASVGPQSYGGGMRPP-PNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSS 255
           + +         +GP    G   PP P+ L G G P    GPG+ G    P G+  P   
Sbjct: 181 IGQ------KGEIGPMGIPGPQGPPGPHGLPGIGKPG---GPGLPGQ-PGPKGDRGPKGL 230

Query: 256 SSPGSYTGPPG--GGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGAGRANFPLGPGPE 312
             P    GP G  G G PG P +  P         M+    P+G  G G+      PGP+
Sbjct: 231 PGPQGLRGPKGDKGFGMPGAPGVKGP-------PGMHGPPGPVGLPGVGKPGVTGFPGPQ 283

Query: 313 GPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG----AVAGLSNAPGTPRDDGEMAAAG 366
           GP+    A       G +G   + G P   PG       G+   PG P   GE    G
Sbjct: 284 GPLGKPGAPGEPGPQGPIGVPGVQG-PPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPG 340



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 89/307 (28%), Positives = 106/307 (34%), Gaps = 53/307 (17%)

Query: 107 APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFM--SPRFPGGPRPTLRMPS 164
           APG+    G +     QGPPG          P +G  GQ  +   P FPGG +    +P 
Sbjct: 291 APGEPGPQGPIGVPGVQGPPG---------IPGIGKPGQDGIPGQPGFPGG-KGEQGLPG 340

Query: 165 QP-PAGLPG-SQPLLPGAMEP----------SPRAQ----GHPSMGGPMQR--------- 199
            P P GLPG  +P  PG               PR +    G P +GGP            
Sbjct: 341 LPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGP 400

Query: 200 VTPPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSS 257
           + PP  +   GP+  GG  G + PP     PGL      PG  G    P    +P     
Sbjct: 401 MGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLP-GPIG 459

Query: 258 PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGA-GRANFPLGPGPEGPMA 316
           P    G  G  G PG P +  P               P  QG  G    P   GP GP+ 
Sbjct: 460 PKGEAGQKGVPGLPGVPGLLGPKGEPGI---------PGDQGLQGPPGIPGIGGPSGPIG 510

Query: 317 AMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSES 376
                 P    G  G     G+ K  PG VAGL   PG P   G     G    P P   
Sbjct: 511 PPGIPGPKGEPGLPGPPGFPGIGK--PG-VAGLHGPPGKPGALGPQGQPGLPGPPGPPGP 567

Query: 377 YSPGMTM 383
             P   M
Sbjct: 568 PGPPAVM 574



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 84/284 (29%), Positives = 109/284 (38%), Gaps = 43/284 (15%)

Query: 122 FQGPPGSQPSPHNPNAPMMGPHGQ--PFMSPRFPGGPR----PTLRMPSQPPA--GLPGS 173
           F GP G +     P A  +GP G+  P  +P   G P     P +  P  PP   G PG 
Sbjct: 355 FPGPKGDRGMGGVPGA--LGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGP 412

Query: 174 Q-------PLLPGAMEPSPRAQGHPSMGGPMQRVTPP--RGMAS-VGPQSYGGGMRPPPN 223
           +       P  P   +  P  QG P   G +  V PP  RG+   +GP+   G  +  P 
Sbjct: 413 KGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAG-QKGVPG 471

Query: 224 SLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS-PGDS 282
               PGL      PG+ G         IP     P    GPPG  GP G P +P  PG  
Sbjct: 472 LPGVPGLLGPKGEPGIPGDQGLQGPPGIP-GIGGPSGPIGPPGIPGPKGEPGLPGPPGFP 530

Query: 283 TNSSENMYTIMNPIGQ-GA----GRANFPLGPGPEGPMAAMSAMEP-----HHVNGSLGS 332
                 +  +  P G+ GA    G+   P  PGP GP    + M P           +G 
Sbjct: 531 GIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGL 590

Query: 333 GDMDGL-PKSSPGAVAGLSNAPG--TPRDDGEMAAAGTFLHPFP 373
           G +DG+ P  + GA  G +  P    P    E+ A      PFP
Sbjct: 591 G-IDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTA------PFP 627


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 87/310 (28%), Positives = 106/310 (34%), Gaps = 62/310 (20%)

Query: 124  GPPGSQPSPHNP-------NAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPA-GLPGS-- 173
            GPPG Q  P  P       +   MGPHG P   PR P GP  +   P  P   G PG+  
Sbjct: 1145 GPPGLQGLPGPPGEKGEVGDVGSMGPHGAP--GPRGPQGPTGSEGTPGLPGGVGQPGAVG 1202

Query: 174  ---------QPLLPGAME-PSPRAQ-------GHPSMGGPMQRVTPPR---GMASVGPQS 213
                      P  PGA   P P+         G     GP  +  PP       SVGP  
Sbjct: 1203 EKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTG 1262

Query: 214  YGGGMRPP-----------------PNSLAGPGLPAMNMGPGVRGPWAS--PSGNSIPYS 254
              G + PP                 P  + GPG P  +  PG  GP     PSG+     
Sbjct: 1263 LPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREG 1322

Query: 255  SSSPGSYTGPPGGGGPPGT--PIMPSPGDSTNSSENMYTIMNPIGQ----GAGRANFPLG 308
                    G PG  GPPG   P+           E +  I  P+G+    GA     P G
Sbjct: 1323 REGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPG 1382

Query: 309  P-GPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----KSSPGAVAGLSNAPGTPRDDGEMA 363
            P GP G         P    G +G   + G P    +     + G+   PG   D G   
Sbjct: 1383 PLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442

Query: 364  AAGTFLHPFP 373
              G+  HP P
Sbjct: 1443 PIGSLGHPGP 1452



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 85/266 (31%), Positives = 96/266 (36%), Gaps = 46/266 (17%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHGQ-PFMSPRFPGGPRPTL--------------RMPSQPP 167
            +GPPG Q     P  P  G  G+  F     P GP   L              R P  PP
Sbjct: 883  KGPPGHQGKDGRPGHP--GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940

Query: 168  AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAG 227
             G PG Q L PG +E    A+G     GP+ +  P       GP+  GG   P P  L G
Sbjct: 941  -GPPGEQGL-PG-LEGREGAKGELGPPGPLGKEGPAGLRGFPGPK--GGPGDPGPTGLKG 995

Query: 228  ----PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDST 283
                PG    N  PG RGP     G  +P  S S G   GP G  G  G    P P    
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGP-VGPAGKKGSRGERGPPGPTGKD 1054

Query: 284  NSSENMYTIMNPIGQGAGRANFPLG-PGPEGPMAAMSAMEPHHVNGSLGS-GDM-DGLPK 340
                    I  P+G        PLG PG  GP             G  GS GD  D  P 
Sbjct: 1055 G-------IPGPLG--------PLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPP 1099

Query: 341  SSPGAVAGLSNAPGTPRDDGEMAAAG 366
              PG + G +  PG P  DG     G
Sbjct: 1100 GQPG-IRGPAGHPGPPGADGAQGRRG 1124



 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 82/283 (28%), Positives = 98/283 (34%), Gaps = 45/283 (15%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHGQPFMS----PRFPGGPRPTLRMPSQPPAGLPGSQPLLP 178
            QG PG+ P P   + P  GP GQ   +    P    G +  L +P     GLPG     P
Sbjct: 748  QGKPGA-PGPRGEDGPE-GPKGQAGQAGEEGPPGSAGEKGKLGVP-----GLPG----YP 796

Query: 179  GAMEPSPRAQ-GHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGP 237
            G   P P+   G P   GP+      +G +    Q    G R PP S    G P     P
Sbjct: 797  G--RPGPKGSIGFPGPLGPIGE----KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQP 850

Query: 238  GVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS----PGDSTNSSENMYT-- 291
            G +G         IP     PG   GPPG  GP G P        PG      E  +   
Sbjct: 851  GPKGDVGQDGAPGIPGEKGLPG-LQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ 909

Query: 292  --------IMNPIGQGAGRANFPLG----PGPEGPMAAMSAMEPHHVNGSLGS-GDMDGL 338
                    ++ P  QG      PLG    PGP GP             G+ G  G    L
Sbjct: 910  TGPPGPAGVLGP--QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPL 967

Query: 339  PKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP-SESYSPG 380
             K  P  + G     G P D G     G    P P   + SPG
Sbjct: 968  GKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 84/314 (26%), Positives = 96/314 (30%), Gaps = 67/314 (21%)

Query: 85  GEAKAFQDYSAAAAPSPVMGSMA--PGDTMAAGSMAAGFFQGPPG--SQPSPHNPNAP-- 138
           G   +FQ   A A       SM   PG     G        G PG   +     P  P  
Sbjct: 456 GPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRG 515

Query: 139 MMGPHGQPFMSPRF--PGG------PRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQ-G 189
           + GPHG P    +   PG       P  T     +   GLPG    LPG  E   R   G
Sbjct: 516 LQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPG----LPG--EKGQRGDFG 569

Query: 190 HPSMGGPMQRVTPPRGMASVGPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVRG 241
           H    GP             GP    G        G R  P     PG+  ++  PG +G
Sbjct: 570 HVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKG 629

Query: 242 PWASPS--------GNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS-PGDSTNSSENMYTI 292
               P         GN        P    G PG  GPPG P +P  PG            
Sbjct: 630 NVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSD---------- 679

Query: 293 MNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNA 352
             P+G           PG EGP     A  P       GS    G P   P  V G S  
Sbjct: 680 -GPLGH----------PGHEGPTGEKGAQGPP------GSAGPPGYP--GPRGVKGTSGN 720

Query: 353 PGTPRDDGEMAAAG 366
            G   + GE    G
Sbjct: 721 RGLQGEKGEKGEDG 734



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 68/232 (29%), Positives = 84/232 (36%), Gaps = 36/232 (15%)

Query: 75   PDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHN 134
            P +R    H G      +  A   P P      PG T   G M A   +GPPG       
Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGP---DGPPGRT---GPMGA---RGPPGRVGPEGL 1359

Query: 135  PNAPMMGPHGQPFM--SPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPS 192
               P  GP G+P +  +P   G P P        P+GLPG    L G   P    +GH  
Sbjct: 1360 RGIP--GPVGEPGLLGAPGQMGPPGPL------GPSGLPG----LKGDTGPKGE-KGHIG 1406

Query: 193  MGGPMQRVTPPRGMASVGPQSYGGGMRPP-PNSLAGPGLPAMNMG----PGVRGPWASPS 247
            + G    + PP      G Q   G   PP P    GP  P  ++G    PGV GP     
Sbjct: 1407 LIG---LIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463

Query: 248  GNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQG 299
                P  S  P   TGP    GPPG P  P+             +  P+ +G
Sbjct: 1464 SKGSP-GSMGPRGDTGP---AGPPGPPGAPAELHGLRRRRRFVPVPLPVVEG 1511



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 52/219 (23%), Positives = 66/219 (30%), Gaps = 73/219 (33%)

Query: 220 PPPNSLAGPGLPAM-NMGPGVRGPWASPSGNSIPYSSSSPG--SYTGPPGGGGPPGTPIM 276
           P        G PA+   G    GP  +P    +   S  PG   + G PG  GP G P +
Sbjct: 370 PGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGI 429

Query: 277 P-------------------------SPGDSTNSSENMYTIM----------NPIG---- 297
           P                          P  S   ++    +            P+G    
Sbjct: 430 PGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGR 489

Query: 298 ------------QGAGRANFPLGP----GPEGPMAAMSAMEPHHVNGSLG-------SGD 334
                       +G   A  P GP    GP GP   +  M     +G+ G        GD
Sbjct: 490 PGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGD 549

Query: 335 --MDGLPKSSPGAVA-----GLSNAPGTPRDDGEMAAAG 366
              DGLP   PG        G    PG P +DGE  A G
Sbjct: 550 RGFDGLP-GLPGEKGQRGDFGHVGQPGPPGEDGERGAEG 587


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 85/281 (30%), Positives = 100/281 (35%), Gaps = 53/281 (18%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAME 182
           +GPPG    P  P     G HGQP      P GP    RM    P GLPG     PG   
Sbjct: 88  RGPPGPPGFPGKPGMGKPGLHGQPG-----PAGPPGFSRMGKAGPPGLPGKVGP-PG--- 138

Query: 183 PSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGP 242
             P  +G P + G      PP      GP   G  +   P +   PG P     PG +G 
Sbjct: 139 -QPGLRGEPGIRGDQGLRGPPGPPGLPGPS--GITIPGKPGAQGVPGPPGFQGEPGPQGE 195

Query: 243 WASPSGNSIPYSSS--SPGSYTGPPGGGGPPGTPIMP---------------SPGDSTNS 285
              P    +   +    PG   G PG GG PG P +P               +PGD   S
Sbjct: 196 PGPPGDRGLKGDNGVGQPG-LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGES 254

Query: 286 SENMYTIMNPIGQ-GAGRANFPLG------------PGPEGPMAAM---SAMEPHHVNGS 329
                 +  P G+ GA     P G            PGP+GP  A        P  + G 
Sbjct: 255 GPP--GVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGP 312

Query: 330 LGSGDMDGLP----KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
            G G M GLP       P  V GL    G P +DGE    G
Sbjct: 313 TGYG-MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQG 352



 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 87/287 (30%), Positives = 105/287 (36%), Gaps = 51/287 (17%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNP-NAPMMGPHGQPFMSPRFPGGPR 157
           P P  G   PG   A G      FQG PG Q  P  P +  + G +G     P  PG P 
Sbjct: 164 PGP-SGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG--VGQPGLPGAPG 220

Query: 158 PTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRG----MASVGPQS 213
              +  +  P GLPG   L    ++  P A G     GP   V  PRG    +   GP  
Sbjct: 221 ---QGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGP-PGVPGPRGEPGAVGPKGPPG 276

Query: 214 YGGGMRPPPNSLAGPGLPAMNMG-PGVRGP--WASPSGNSIPYSSSSPGSYTGPPGGGGP 270
             G   P    L GP  P+   G PG RGP     P+G  +P          GP G  GP
Sbjct: 277 VDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMP-------GLPGPKGDRGP 329

Query: 271 PGTPIM----PSPGDSTNSSENMYTIMNPIGQGA-----GRANFPLGPGPEGPMAAMSAM 321
            G P +      PG+     E       P G G      G A  P   GP GP       
Sbjct: 330 AGVPGLLGDRGEPGEDGEPGE-----QGPQGLGGPPGLPGSAGLPGRRGPPGP------- 377

Query: 322 EPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                 G  G G   G+P  +   G  +GL+  PG P + G   A G
Sbjct: 378 -----KGEAGPGGPPGVPGIRGDQGP-SGLAGKPGVPGERGLPGAHG 418



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 76/256 (29%), Positives = 87/256 (33%), Gaps = 65/256 (25%)

Query: 141 GPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRV 200
           GP G PF       G    L MP           PLLP  ++  P   G P   GP    
Sbjct: 50  GPVGPPFRE-----GKGQYLEMPL----------PLLPMDLKGEPGPPGKPGPRGP---P 91

Query: 201 TPP-----RGMASVGPQSYGGGMRPP-------------PNSLAGPGLPAMNMGPGVRGP 242
            PP      GM   G     G   PP             P  +  PG P +   PG+RG 
Sbjct: 92  GPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGD 151

Query: 243 WA-----------SPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS-PGDSTNSSENMY 290
                         PSG +IP    + G   GPPG  G PG    P  PGD     +N  
Sbjct: 152 QGLRGPPGPPGLPGPSGITIPGKPGAQG-VPGPPGFQGEPGPQGEPGPPGDRGLKGDN-- 208

Query: 291 TIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLS 350
                   G G+   P  PG  G         P      LG   +DGLP  +PG   G S
Sbjct: 209 --------GVGQPGLPGAPGQGGAPGPPGLPGP----AGLGKPGLDGLP-GAPGD-KGES 254

Query: 351 NAPGTPRDDGEMAAAG 366
             PG P   GE  A G
Sbjct: 255 GPPGVPGPRGEPGAVG 270



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 58/162 (35%), Positives = 66/162 (40%), Gaps = 30/162 (18%)

Query: 124 GPPGSQ--PSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAM 181
           G PG +  P  H P  P  GP G+P  + R PGGP     +  +   GLPG     PG  
Sbjct: 406 GVPGERGLPGAHGPPGPT-GPKGEPGFTGR-PGGPGVAGALGQKGDLGLPGQ----PGLR 459

Query: 182 EPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRG 241
            PS    G P + GP            +GPQ   G    P   L GP        PG  G
Sbjct: 460 GPS----GIPGLQGPA---------GPIGPQGLPGLKGEP--GLPGPPGEGRAGEPGTAG 504

Query: 242 PWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDST 283
           P   P    +P    SPG  TGPPG  GPPG P  P   D T
Sbjct: 505 PTGPPG---VP---GSPG-ITGPPGPPGPPGPPGAPGAFDET 539



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 77/253 (30%), Positives = 94/253 (37%), Gaps = 43/253 (16%)

Query: 123 QGPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAM 181
           QGP G++  P     P ++GP G        PG P P      + PAG+PG   LL    
Sbjct: 292 QGPSGAKGEPGTRGPPGLIGPTGYGM-----PGLPGPK---GDRGPAGVPG---LLGDRG 340

Query: 182 EPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRG 241
           EP     G P   GP     PP    S G     G   P P   AGPG P     PG+RG
Sbjct: 341 EPGE--DGEPGEQGPQGLGGPPGLPGSAGLPGRRGP--PGPKGEAGPGGPPGV--PGIRG 394

Query: 242 PWASPSGNS----IPYSSSSPGSYTGPPGGGGPPGTP-IMPSPGDSTNSSENMYTIMNPI 296
               PSG +    +P     PG++ GPPG  GP G P     PG           +   +
Sbjct: 395 D-QGPSGLAGKPGVPGERGLPGAH-GPPGPTGPKGEPGFTGRPGGPG--------VAGAL 444

Query: 297 GQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP---------KSSPGAVA 347
           GQ  G    P  PG  GP        P    G  G   + G P         ++     A
Sbjct: 445 GQ-KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTA 503

Query: 348 GLSNAPGTPRDDG 360
           G +  PG P   G
Sbjct: 504 GPTGPPGVPGSPG 516



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 75/276 (27%), Positives = 94/276 (34%), Gaps = 43/276 (15%)

Query: 108 PGDTMAAGSMAAGFFQGPPG----------SQPSPHNPNAP-----MMGPHGQPFMSPRF 152
           PG    +G+      +GPPG            P P     P     ++G  G+P      
Sbjct: 289 PGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGE- 347

Query: 153 PGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQ 212
           PG   P        P GLPGS   LPG   P P  +G    GG       P G+  +   
Sbjct: 348 PGEQGP---QGLGGPPGLPGSAG-LPGRRGP-PGPKGEAGPGG-------PPGVPGIRGD 395

Query: 213 SYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPG 272
               G+   P      GLP  +  PG  GP   P     P      G+  G  G  G PG
Sbjct: 396 QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGA-LGQKGDLGLPG 454

Query: 273 TPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGS 332
            P +  P    +    +     PIG   G       PG  GP     A EP    G+ G 
Sbjct: 455 QPGLRGP----SGIPGLQGPAGPIGP-QGLPGLKGEPGLPGPPGEGRAGEP----GTAGP 505

Query: 333 GDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTF 368
               G+P S      G++  PG P   G   A G F
Sbjct: 506 TGPPGVPGS-----PGITGPPGPPGPPGPPGAPGAF 536



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 34/119 (28%), Positives = 39/119 (32%), Gaps = 8/119 (6%)

Query: 263 GPPGGGGPPGTPIMPS-PGDSTNSSENMYTIMNPIG----QGAGRANFPLGPGPEGPMAA 317
           GPPG  GP G P  P  PG        ++    P G       G+A  P  PG  GP   
Sbjct: 80  GPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQ 139

Query: 318 MSAMEPHHVNGS---LGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                   + G     G     GLP  S   + G   A G P   G     G    P P
Sbjct: 140 PGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGP 198



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 35/124 (28%), Positives = 37/124 (29%), Gaps = 32/124 (25%)

Query: 258 PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAA 317
           P    GP G  GPPG P  P                     G G+      PGP GP   
Sbjct: 81  PPGKPGPRGPPGPPGFPGKP---------------------GMGKPGLHGQPGPAGPPGF 119

Query: 318 MSAMEPHHVNGSLGSGDMDGLP-KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSES 376
                       +G     GLP K  P    GL   PG   D G     G    P PS  
Sbjct: 120 ----------SRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGI 169

Query: 377 YSPG 380
             PG
Sbjct: 170 TIPG 173


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 71/233 (30%), Positives = 79/233 (33%), Gaps = 26/233 (11%)

Query: 99  PSPVMGSMAPGDTMAAGSMAA-GFFQGPP---GSQPSPHNPNAPMMGPHGQPFMSPRFPG 154
           P    G    GD  +  S +  G  QGPP   G+QP    P  P   P G P      P 
Sbjct: 156 PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGNKPQ 213

Query: 155 GPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSY 214
           GP P  +    PP G   SQ     A  P  + QG P  GG   +  PP      GP   
Sbjct: 214 GPPPPGKPQGPPPQGDNKSQ----SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269

Query: 215 GGGMR---PPPNSLAGPGLPAMNMGPGVRGPWASPSG------NSIPYSSSSPGSYTGPP 265
           GG      PPP    GP     +     R P   P G      N        PG   GPP
Sbjct: 270 GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329

Query: 266 GGGG-------PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGP 311
             GG       PPG P  P P   + S         P G      N P GP P
Sbjct: 330 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 81/292 (27%), Positives = 91/292 (31%), Gaps = 32/292 (10%)

Query: 91  QDYSAAAAPSPVMGSM--AP---GDTMAAGSMAAGFFQGPPGSQP-SPHNPNAPMMGPHG 144
           +D S   +PS + G+   AP   G+         G  QGPP      P  P  P   P G
Sbjct: 21  EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 80

Query: 145 QPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPR 204
            P      P GP P  +    PP G     P       P  + QG P  GG   +  PP 
Sbjct: 81  PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP-----RSPPGKPQGPPPQGGNQPQGPPPP 135

Query: 205 GMASVGPQSYGGGM---RPPPNSLAGPGLPAMNMGPGVRGPWASP------SGNSIPYSS 255
                GP   GG      PPP    GP     N     R P   P       GN      
Sbjct: 136 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP 195

Query: 256 SSPGSYTGPPGGGG-------PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG 308
             PG   GPP  GG       PPG P  P P     S         P G      N P G
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG 255

Query: 309 PGPEGPMAAMSAMEPHHVNGSLG---SGDMDGLPKSSPGAVAGLSNAPGTPR 357
           P P  P        P   N   G    G   G P           + PG P+
Sbjct: 256 PPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ 305



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 58/192 (30%), Positives = 68/192 (35%), Gaps = 22/192 (11%)

Query: 99  PSPVMGSMAPGDTMAAGSMAA-GFFQGPP---GSQPSPHNPNAPMMGPHGQPFMSPRFPG 154
           P    G    GD  +  + +  G  QGPP   G+QP    P  P   P G P      P 
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGNKPQ 275

Query: 155 GPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSY 214
           GP P  +    PP G   S+     +  P  + QG P  GG   +  PP      GP   
Sbjct: 276 GPPPPGKPQGPPPQGGSKSR----SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331

Query: 215 GGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTG------PPGGG 268
           GG      N   GP  P    GP  +G   S S  S P     P    G      PP  G
Sbjct: 332 GG------NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385

Query: 269 GPPGTPIMPSPG 280
           G P  P  P  G
Sbjct: 386 GNPQQPQAPPAG 397


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 103/347 (29%), Positives = 118/347 (34%), Gaps = 70/347 (20%)

Query: 95  AAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQ--------PSPHNPNAPMMGPHGQP 146
           AA  P P   +  PG   A G+      QGP GS+        P P  P A   GP G P
Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP-AGAAGPAGNP 388

Query: 147 FM-----------SPRFPGGPR-PTLRMPSQP--PAGLPG-----SQPLLPGAM------ 181
                        +P   G P  P  R PS P  P G PG      +P  PG+       
Sbjct: 389 GADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK 448

Query: 182 -EPSP-RAQGHPSMGGPM----QRVTP-PRGMASVGPQSYGGGMR--PPPNSLAGPGLPA 232
            EP P   QG P   G       R  P P G+     +  G G R  P  + +AGP  PA
Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA 508

Query: 233 MNMG-PGVRGPWASPSGNSIPYSSSSPGSY--------------TGPPGGGGPPGTPIMP 277
              G PG  GP  SP     P  +  PG+               TGPPG  G  G P  P
Sbjct: 509 GERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP 568

Query: 278 SPGDSTNSSENMYTIMNPIGQG-----AGRANFPLGPGPEGPM---AAMSAMEPHHVNGS 329
            P         +     P G       AG    P  PG  GP        A  P    G 
Sbjct: 569 GP-PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGP 627

Query: 330 LGSGDMDGLPKSSPG--AVAGLSNAPGTPRDDGEMAAAGTFLHPFPS 374
            G     G P  SPG   + G +  PG     GE    G    P PS
Sbjct: 628 AGERGEQG-PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673



 Score = 72.0 bits (175), Expect = 8e-13
 Identities = 89/291 (30%), Positives = 103/291 (35%), Gaps = 52/291 (17%)

Query: 94   SAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMGPHGQPFMS 149
            S  A P+   G  APGD    G      F GPPG+   P     P      G  G P   
Sbjct: 787  SGPAGPTGARG--APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP--G 842

Query: 150  PRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASV 209
            P  P GP   +     P  G  G++    G+  P P A G P   G   RV PP      
Sbjct: 843  PAGPAGPPGPIGNVGAP--GAKGAR----GSAGP-PGATGFPGAAG---RVGPP------ 886

Query: 210  GPQSYGGGMRPPPNSLAGPGLPAMNMGP-GVRGPWASPSGNSIPYSSSSPGSYTGPPGGG 268
            GP    G   PP     GP       GP G  GP   P G   P     P    G PG  
Sbjct: 887  GPSGNAGPPGPP-----GPAGKEGGKGPRGETGPAGRP-GEVGPPGPPGPAGEKGSPGAD 940

Query: 269  GPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGP------EGPMAAMSAME 322
            GP G P  P P            ++   GQ  G   FP  PGP      +GP  A     
Sbjct: 941  GPAGAPGTPGP----QGIAGQRGVVGLPGQ-RGERGFPGLPGPSGEPGKQGPSGASGERG 995

Query: 323  PHHVNGSLGSGDMDGLP-----KSSPGAVA--GLSNAPGTPRDDGEMAAAG 366
            P    G +G   + G P     + +PGA    G   +PG   D GE   AG
Sbjct: 996  P---PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAG 1043



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 80/278 (28%), Positives = 92/278 (33%), Gaps = 39/278 (14%)

Query: 124 GPPGSQPSPHNPNAP-MMGPHGQPFMSPRFPGGPRPT----------LRMPSQP--PAGL 170
           GP G   SP    AP  MGP G P    R PG P P              P  P  PAG 
Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGPPGPTGPAGP 342

Query: 171 PG----------SQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRP 220
           PG          + P  P   E     +G P   GP      P G      Q    G   
Sbjct: 343 PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG-AAGPAGNPGADGQPGAKGANG 401

Query: 221 PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMPS 278
            P     PG P      G +GP   P          +PGS   TG  G  GP G    P 
Sbjct: 402 APGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG 461

Query: 279 PGD-----STNSSENMYTIMNPIGQ--GAGRANFPLG---PGPEGPMAAMSAMEPHHVNG 328
           P                 +  P G+  G G   FP      GP+GP     +  P    G
Sbjct: 462 PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG 521

Query: 329 SLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           S G     G     PGA  GL+ +PG+P  DG+    G
Sbjct: 522 SPGEAGRPG-EAGLPGA-KGLTGSPGSPGPDGKTGPPG 557



 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 93/311 (29%), Positives = 114/311 (36%), Gaps = 53/311 (17%)

Query: 92  DYSAAAAPSP--VMGSMAP----GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP----MMG 141
           D  A   P P  V G   P    G   A G        GPPG +  P +   P    + G
Sbjct: 444 DTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG 503

Query: 142 PHGQPFM--SPRFPGGPRPTLRMPSQP-PAGLPGSQPLLPGAMEPSPRAQ-GHPSMGGPM 197
           P G      SP  P GP+ +     +P  AGLPG++ L      P P  + G P   G  
Sbjct: 504 PKGPAGERGSPG-PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 198 QRVTPP-----RGMASV----GPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVR 240
            R  PP     RG A V    GP+   G        G+  PP ++   G        G  
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPP 622

Query: 241 GPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS----PGDSTNSSENMYTIMNPI 296
           GP A P+G       +    + G PG  GPPG    P     PGD          +  P 
Sbjct: 623 GP-AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGD----------LGAPG 671

Query: 297 GQGA-GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGT 355
             GA G   FP   G +GP        P   NG+ G+    G    +PGA  G   APG 
Sbjct: 672 PSGARGERGFPGERGVQGPPGPAG---PRGANGAPGNDGAKG-DAGAPGA-PGSQGAPGL 726

Query: 356 PRDDGEMAAAG 366
               GE  AAG
Sbjct: 727 QGMPGERGAAG 737



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 92/327 (28%), Positives = 114/327 (34%), Gaps = 54/327 (16%)

Query: 97  AAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGP 156
           + P P+  S   G     G+     FQGPPG +P     + P MGP G P   P    G 
Sbjct: 176 SVPGPMGPSGPRGLPGPPGAPGPQGFQGPPG-EPGEPGASGP-MGPRGPP--GPPGKNGD 231

Query: 157 RPTLRMPSQP-PAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMAS-VGPQ 212
                 P +P   G PG Q    LPG     P  +GH    G    +   +G A   GP+
Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGT-AGLPGMKGHRGFSG----LDGAKGDAGPAGPK 286

Query: 213 SYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGP 270
              G  G    P  +   GLP     PG  GP A   GN     ++ P   TGP G  G 
Sbjct: 287 GEPGSPGENGAPGQMGPRGLPGERGRPGAPGP-AGARGNDGATGAAGPPGPTGPAGPPGF 345

Query: 271 PGT------------------------PIMPSPGDSTNSSENMYTIMNPIGQG------- 299
           PG                         P  P P  +   + N      P  +G       
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 300 AGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDG--LPKSSPGAVAGLSNAPGTPR 357
           AG   FP   GP GP        P   +G  G+    G    K  PG V G+   PG   
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV-GVQGPPGPAG 464

Query: 358 DDGEMAAAG----TFLHPFPSESYSPG 380
           ++G+  A G    T L   P E   PG
Sbjct: 465 EEGKRGARGEPGPTGLPGPPGERGGPG 491



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 104/367 (28%), Positives = 123/367 (33%), Gaps = 92/367 (25%)

Query: 96   AAAPSPVMGSMAPGDTMAAGSM----AAGF-----FQGPPGSQPSPHNPNAPMMGPHGQP 146
            A  P P+    APG   A GS     A GF       GPPG   +   P  P  GP G+ 
Sbjct: 847  AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP--GPAGKE 904

Query: 147  F-MSPRFPGGP--RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPP 203
                PR   GP  RP    P  PP   P  +   PGA  P+    G P   GP Q +   
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPG--PAGEKGSPGADGPA----GAPGTPGP-QGIAGQ 957

Query: 204  RGMASV-------------GPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVRGP 242
            RG+  +             GP    G        G R PP  +  PGL      PG  G 
Sbjct: 958  RGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP---PGESGR 1014

Query: 243  WASPSGNSIPYSSSSPGSY-----TGPPGGGGPPGTPIMPSP-GDSTNSSENMYT----- 291
              +P     P    SPG+      TGP G  G PG P  P P G +  S +   T     
Sbjct: 1015 EGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGP 1074

Query: 292  --IMNPIG-------------------QG----AGRANF---------PLGPGPEGPMAA 317
               + P+G                   QG     G   F         P  PG +GP  A
Sbjct: 1075 AGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134

Query: 318  MSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESY 377
                 P    GS G+   DGL    PG + G     G   D G +   G    P P    
Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGL-NGLPGPI-GPPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192

Query: 378  SPGMTMS 384
            S G   S
Sbjct: 1193 SAGFDFS 1199



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 78/259 (30%), Positives = 98/259 (37%), Gaps = 43/259 (16%)

Query: 125 PPGSQPSPHNPNAPMMGPHGQPF-MSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP 183
           P GS+         + GP G      PR P GP      P +   G+PG QP LPG   P
Sbjct: 96  PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGP------PGRD--GIPG-QPGLPGPPGP 146

Query: 184 SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGP-GLPAMNMGPGVRGP 242
            P   G P +GG       P+       +S GG   P P   +GP GLP     PG +G 
Sbjct: 147 -PGPPGPPGLGGNF----APQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG- 200

Query: 243 WASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGR 302
           +  P G         PG+ +GP G  GPPG      PG + +  E            AG+
Sbjct: 201 FQGPPG-----EPGEPGA-SGPMGPRGPPG-----PPGKNGDDGE------------AGK 237

Query: 303 ANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGA-VAGLSNAPGTPRDDGE 361
              P   GP GP  A        + G  G     GL  +   A  AG    PG+P ++G 
Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297

Query: 362 MAAAGTFLHPFPSESYSPG 380
               G      P E   PG
Sbjct: 298 PGQMGP--RGLPGERGRPG 314



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 89/313 (28%), Positives = 113/313 (36%), Gaps = 58/313 (18%)

Query: 99  PSPVMGSMAPG-----DTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRF- 152
           P  + G+ AP      D  + G ++     GP G +  P  P AP  GP G  F  P   
Sbjct: 152 PPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP--GPQG--FQGPPGE 207

Query: 153 PGGPRPTLRMPSQPPAGLPGS--------QPLLPGAM-EPSPR-AQGHPSMGGPMQRVTP 202
           PG P  +  M  + P G PG         +P  PG    P P+ A+G P   G +  +  
Sbjct: 208 PGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG-LPGMKG 266

Query: 203 PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGS-- 260
            RG + +       G   P      PG P  N  PG  GP   P     P +    G+  
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGE---PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG 323

Query: 261 ------YTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG----PG 310
                   GPPG  GP G P  P    +   +           QG   +  P G    PG
Sbjct: 324 NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG---------PQGPRGSEGPQGVRGEPG 374

Query: 311 PEGPMAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAAAGTF 368
           P GP  A          G  G+   DG P  K + GA  G++ APG P   G     G  
Sbjct: 375 PPGPAGAA---------GPAGNPGADGQPGAKGANGA-PGIAGAPGFPGARGPSGPQGPG 424

Query: 369 LHPFP-SESYSPG 380
             P P   S  PG
Sbjct: 425 GPPGPKGNSGEPG 437



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 81/312 (25%), Positives = 101/312 (32%), Gaps = 41/312 (13%)

Query: 85  GEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGP---------PGSQPSPHNP 135
           G A    +  A   P P   +   G+   AGS       GP         PG Q  P + 
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL 667

Query: 136 NAPMMGPHG----------QPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSP 185
            AP  GP G          +    P  P GPR     P    A      P  PG+ + +P
Sbjct: 668 GAP--GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS-QGAP 724

Query: 186 RAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGM-RPPPNSLAGPGLPAMNMGPGVRGPWA 244
             QG P   G      P       GP+   G   +     L GP      +GP   GP  
Sbjct: 725 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP------IGPP--GPAG 776

Query: 245 SPS--GNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGR 302
           +P   G S P   + P    G PG  G PG P          +         P   GA  
Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKG 836

Query: 303 ANFPLGP----GPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----KSSPGAVAGLSNAPG 354
              P GP    GP GP+  + A       GS G     G P    +  P   +G +  PG
Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG 896

Query: 355 TPRDDGEMAAAG 366
            P   G+    G
Sbjct: 897 PPGPAGKEGGKG 908



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 63/203 (31%), Positives = 73/203 (35%), Gaps = 39/203 (19%)

Query: 166 PPAGLPGSQ--PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPN 223
           P A +P  +  P+ P   E SP  Q    + GP +  T PRG     P+   G    PP 
Sbjct: 82  PGAEVPEGECCPVCPDGSE-SPTDQETTGVEGP-KGDTGPRG-----PRGPAG----PPG 130

Query: 224 SLAGPGLPAMNMGPGVRGPWASPS--GNSIP-----YSSSSPG--SYTGPPGGGGPPGTP 274
               PG P +   PG  GP   P   GN  P     Y   S G  S  GP G  GP G P
Sbjct: 131 RDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLP 190

Query: 275 IMP-SPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSG 333
             P +PG              P G+       P  PG  GPM       P   NG  G  
Sbjct: 191 GPPGAPGPQ--------GFQGPPGE-------PGEPGASGPMGPRGPPGPPGKNGDDGEA 235

Query: 334 DMDGLP-KSSPGAVAGLSNAPGT 355
              G P +  P    G    PGT
Sbjct: 236 GKPGRPGERGPPGPQGARGLPGT 258


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 83/285 (29%), Positives = 100/285 (35%), Gaps = 54/285 (18%)

Query: 122  FQGPPGSQPSPHNPNAP----------MMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGL- 170
            F GPPG       P  P           MGP G P   PR P G  P    P  PP G+ 
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP--GPRGPSGA-PGADGPQGPPGGIG 1276

Query: 171  -PGS-----------QPLLPG-AMEPSPRAQ-GHPSMGGPMQRVTPP--RG-------MA 207
             PG+           +P LPG    P P+ + G     GP     PP  +G         
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336

Query: 208  SVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGG 267
            S GP  + G   PP      PG    +  PG +G    P     P  +  PG  +GPPG 
Sbjct: 1337 SPGPVGFPGDPGPPGE----PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP-SGPPGK 1391

Query: 268  GGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVN 327
             GPPG P  P        ++    +  P G+           GP GP  A     P  + 
Sbjct: 1392 RGPPG-PAGPEGRQGEKGAKGEAGLEGPPGK----------TGPIGPQGAPGKPGPDGLR 1440

Query: 328  GSLGSGDMDGLPKS-SPGAVAGLSNAPGTPRDDGEMAAAGTFLHP 371
            G  G     GLP S  P    G    PG P   G+    G   HP
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHP 1485



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 87/273 (31%), Positives = 102/273 (37%), Gaps = 37/273 (13%)

Query: 94   SAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPG--SQPSPHNPNAPM--MGPHGQPFMS 149
            S AA P    G   PGD    GS     F G PG   +P P   + P    G  G+P  +
Sbjct: 1317 SGAAGPPGPKGP--PGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQT 1374

Query: 150  PRFPGGPRPTLRMPSQP-PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMAS 208
                G P PT     +P P+G PG +   PG   P  R QG     G      PP     
Sbjct: 1375 ----GSPGPT----GEPGPSGPPGKRGP-PGPAGPEGR-QGEKGAKGEAGLEGPPGKTGP 1424

Query: 209  VGPQSYGGGMRPPPNSLAG----------PGLPAMNMGPGVRGPWASPS--GNSIPYSSS 256
            +GPQ   G  +P P+ L G          PG P  +  PG  GP   P   G+S P    
Sbjct: 1425 IGPQGAPG--KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEK 1482

Query: 257  S-PG--SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEG 313
              PG     GPPG  G  G   +P P  S+        I  P G   G    P  PGP G
Sbjct: 1483 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ-GITGPSGP-IGPPGPPGLPGPPG 1540

Query: 314  PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAV 346
            P  A  +  P    G  G     G P   PG V
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPG-PPGPPGEV 1572



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 78/274 (28%), Positives = 92/274 (33%), Gaps = 56/274 (20%)

Query: 124  GPPG--SQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ------- 174
            GPPG   +  P  P     GP+G P   P  P G +  L +P  P  G PG Q       
Sbjct: 832  GPPGPRGEDGPEGPKG-RGGPNGDP--GPLGPPGEKGKLGVPGLP--GYPGRQGPKGSIG 886

Query: 175  -PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAM 233
             P  PGA       +G P   GP  +  P       GP+   G   P  NS         
Sbjct: 887  FPGFPGA-NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNS--------- 936

Query: 234  NMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPS-PGDSTNSSENMYTI 292
                G  GP A P G   P     P  + GP G  GPPG   +P  PG            
Sbjct: 937  ----GGDGP-AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQ----------- 980

Query: 293  MNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG--AVAGLS 350
                    G   F    GP GP   +    P    G +G     G P   PG   + GL+
Sbjct: 981  -------RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG-PPGPPGEQGLPGLA 1032

Query: 351  NAPGTPRDDGEMAAAG----TFLHPFPSESYSPG 380
               GT  D G     G      L  FP +   PG
Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPG 1066



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 88/297 (29%), Positives = 104/297 (35%), Gaps = 65/297 (21%)

Query: 109  GDTMAAGSMAAGFFQGPPG--------SQPSPHNPNAPMMGPHGQPFM-------SPR-F 152
            G+    GS      QGPPG         QP P   +    GP GQ  +        PR F
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP-GPRGQQGLFGQKGDEGPRGF 1220

Query: 153  PGGPRPTLRMPSQPPAGLPGS-----QPLLPGAMEPSPRA-QGHPSMGGPMQRVTPPRGM 206
            PG P P        P G  G      Q   PG   P PR   G P   GP     PP G+
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP--PGPRGPSGAPGADGPQG---PPGGI 1275

Query: 207  ASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPW-----ASPSGNSIPYSSSSPGSY 261
             + G      G +  P     PGLP     PG +G       + PSG + P     P   
Sbjct: 1276 GNPGAV----GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGD 1331

Query: 262  TGPPGGGGPPGTPIMPS-------------PGDSTNSSENMYTIMNPIGQGAGRANFPLG 308
             GP G  GP G P  P              PGD  +  E   T  +P   G    + P G
Sbjct: 1332 DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQT-GSPGPTGEPGPSGPPG 1390

Query: 309  ----PGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-KSSPGAVAGLSNAPGTPRDDG 360
                PGP GP             G+ G   ++G P K+ P    G   APG P  DG
Sbjct: 1391 KRGPPGPAGPEGRQGE------KGAKGEAGLEGPPGKTGP---IGPQGAPGKPGPDG 1438



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 85/299 (28%), Positives = 98/299 (32%), Gaps = 38/299 (12%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPN-APMMGPHGQPFM-SPRFPGGPRPTLRMPS- 164
            PG   A G        GPPG   SP     A   GP G P    P+ P GP      P  
Sbjct: 1065 PGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGE 1124

Query: 165  ---QPPAGLPGSQ-PL-LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMR 219
               Q PAG  G Q P+ LPG   P     G P   G    +  P    S G +   G   
Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPV----GPPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180

Query: 220  P--PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP 277
            P  P   +  PG    +  PG RG      G         P  + GPPG  G  G P  P
Sbjct: 1181 PTGPQGPIGQPGPSGADGEPGPRGQ----QGLFGQKGDEGPRGFPGPPGPVGLQGLPGPP 1236

Query: 278  SPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDG 337
                 T     M     P  +G   A  P   GP+GP   +         G  G     G
Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGA--PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294

Query: 338  LP----------------KSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
            LP                +S P   AG     G P DDG   + G     FP +   PG
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV--GFPGDPGPPG 1351



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 68/226 (30%), Positives = 89/226 (39%), Gaps = 53/226 (23%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQ--PSPHNPN-----------APMMGPHGQ-----PFMS 149
            PG T + G        GPPG +  P P  P            A + GP G+     P  +
Sbjct: 1371 PGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGA 1430

Query: 150  PRFPG--------GPRPTLRMPSQP-PAGLPGSQ--PLLPGAMEPS-PRAQ-GHPSMGGP 196
            P  PG        GP     +P  P P G PG    P LPG    S P+ + GHP + G 
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIG- 1489

Query: 197  MQRVTPP--------RGMASVGPQSYGG-----GMRPPPNSLAGPGLPAMNMGPGVRGPW 243
               + PP        RG+   GPQ   G     G+  P   +  PG P +   PG +G  
Sbjct: 1490 --LIGPPGEQGEKGDRGLP--GPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA- 1544

Query: 244  ASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENM 289
                G+S P        + GPPG  GPPG  I P P  ++ +  N+
Sbjct: 1545 ---KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNI 1587



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 92/352 (26%), Positives = 108/352 (30%), Gaps = 77/352 (21%)

Query: 99   PSPVMGSMAP-GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPR 157
            P+   G   P G T   G        GP G  P    PN P  GP G P   P+ P GP 
Sbjct: 914  PTGPRGERGPRGITGKPGPKGNSGGDGPAGP-PGERGPNGPQ-GPTGFP--GPKGPPGPP 969

Query: 158  PTLRMPSQP-------------PAGLPGSQPLLPGAMEPSPRAQ-GHPSMGGPMQRVTPP 203
                +P  P             P G PG         E  P  + GHP   GP      P
Sbjct: 970  GKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029

Query: 204  RGMASV-------GPQSYGGGMRPP-----------PNSLAGPGLPAMNMGPGVRGPWAS 245
             G+A         GP    G   PP           P  +   GL      PG  GP  S
Sbjct: 1030 -GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 246  PSGNSIPYSSSSPGSYTGPPGGGGPPGT-----------PIMPSPGDSTNSSENMYTIMN 294
            P G   P  ++ P    G PG  GPPG            P  P+  D       +     
Sbjct: 1089 P-GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147

Query: 295  PIG-QGAGRANFPLG----------------PGPEGPMAAMSAMEPHHVNGSLGSGDMDG 337
            P+G  G       +G                PGP GP   +    P   +G  G     G
Sbjct: 1148 PVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG 1207

Query: 338  L--------PKSSPG--AVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSP 379
            L        P+  PG     GL   PG P + GE    G    P P     P
Sbjct: 1208 LFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGP 1259



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 79/281 (28%), Positives = 95/281 (33%), Gaps = 57/281 (20%)

Query: 124 GPPGSQPSPHNPNAPMMGPHGQPFMSPR-FPGGPRPTLRMPSQPPAGLPGSQPLLPGAME 182
           GPPGS      P    +GP G     PR   G P P  +   +  AG  G++ + PG   
Sbjct: 574 GPPGSGGLKGEPGD--VGPQG-----PRGVQGPPGPAGKPGRRGRAGSDGARGM-PGQTG 625

Query: 183 PS-----------PRAQGHPSMGGPMQRVTPP-----RGM-ASVGPQSYGG--------G 217
           P            P  +GH    GP     PP     RG    VGP+   G        G
Sbjct: 626 PKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG 685

Query: 218 MRPPPNSLAGPGLPAMNMGPGVRG---PWASPS-----GNSIPYSSSSPGSYTGPPGGGG 269
            + PP     PG+  M+  PG +G   P   P      GN        P    GPPG  G
Sbjct: 686 PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745

Query: 270 P---PGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG-PGPEGPMAAMSAMEPHH 325
           P   PG P MP                   GQG      P+G PGP G   A        
Sbjct: 746 PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGI---RG 802

Query: 326 VNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           + G+ G    DG P        G     G   D GE+   G
Sbjct: 803 LKGTKGEKGEDGFP--------GFKGDMGIKGDRGEIGPPG 835



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 74/260 (28%), Positives = 88/260 (33%), Gaps = 46/260 (17%)

Query: 142 PHGQPFMSPRF--PGGP--RPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPM 197
           P+  P  SP    PG P  + T+      P G  G Q   P  +EP    +G P   GP 
Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKG-QKGEPAIIEPGMLIEGPPGPEGPA 477

Query: 198 QRVTPPRGMASVGPQSYGGGMRPP--PNSLAGPGLP----AMNMGP---------GVRGP 242
               PP  M   G     G   PP  P      GLP     M M P         G +GP
Sbjct: 478 GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGP 537

Query: 243 WASPSGNSIP----------YSSSSPGSYTGPPGGGGPPGT-PIMPSPGDSTNSSENMYT 291
             S   +                + P   TG PG  GPPG+  +   PGD     +    
Sbjct: 538 MVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDV--GPQGPRG 595

Query: 292 IMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVA---- 347
           +  P G  AG+      PG  G   +  A       G  G    DGL    PG       
Sbjct: 596 VQGPPGP-AGK------PGRRGRAGSDGARGMPGQTGPKGDRGFDGL-AGLPGEKGHRGD 647

Query: 348 -GLSNAPGTPRDDGEMAAAG 366
            G S  PG P DDGE    G
Sbjct: 648 PGPSGPPGPPGDDGERGDDG 667



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 48/180 (26%), Positives = 59/180 (32%), Gaps = 34/180 (18%)

Query: 210 GPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG 269
           GP+   G    P  ++  PG+  +   PG  GP   P     P  +  P    G PG  G
Sbjct: 447 GPRGEKGQKGEP--AIIEPGM-LIEGPPGPEGPAGLPG----PPGTMGPTGQVGDPGERG 499

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGP-------------------- 309
           PPG P +P           M  +M P   G G      GP                    
Sbjct: 500 PPGRPGLPGADGLPGPPGTM--LMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLAL 557

Query: 310 -GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKS-SPGAVAGLSNAPGTPRDDGEMAAAGT 367
            GP GPM       P    G  GSG + G P    P    G+   PG     G    AG+
Sbjct: 558 RGPAGPMGLTGRPGP---VGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGS 614


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 94/297 (31%), Positives = 113/297 (38%), Gaps = 49/297 (16%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMSPR-FPGGPRPTLRMPSQ 165
            PG    AG        GP G +  P +   P   G  G+P +  R FPG P       S+
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 166  PPAGLPG--SQPLLPGA------MEPSPRAQGHPSM-GGPMQRVTPPRGMASVGPQSYGG 216
               G PG    P +PG+      M P P  QG P + G P      P+G    GPQ   G
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGP-PGPQGQPGLPGSPGHATEGPKG--DRGPQGQPG 1245

Query: 217  GMRPPPNSLAGPGLPAM--------NMG----PGVRGPWASPSGNSIPYSSSSPGSYTGP 264
             +   P  +  PGLP +        N G    PGV GP   P    +P    SPG  TG 
Sbjct: 1246 -LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG-ITGS 1303

Query: 265  PGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGA-GRANFPLGPGPEGPMAAMSAME 322
             G  GPPG P    P         +  I    G QG  G    P  PGP GP   +   E
Sbjct: 1304 KGDMGPPGVPGFQGP----KGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKG-E 1358

Query: 323  PHHVNGSLGSGDMDGL-----PKSSPG--AVAGLSNAPGTPRDD------GEMAAAG 366
            P  + G  G   + GL     PK   G   + G+   PG P  D      GEM  AG
Sbjct: 1359 P-GLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAG 1414



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 89/297 (29%), Positives = 106/297 (35%), Gaps = 67/297 (22%)

Query: 123 QGPPGSQPSPHNPNAP-------------MMGPHGQPFM--SPRFPGGPRP---TLRMPS 164
           QGPPG    P  P A              + GP G P +   P   G P      LR+  
Sbjct: 482 QGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKG 541

Query: 165 QP-PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVT---------PPRGMASVGPQSY 214
                G PG QP + G    SP   GHP + GP              PP G+   G +  
Sbjct: 542 DKGDPGFPG-QPGMTGRAG-SPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGD 599

Query: 215 GGGMRPPPNSLAGP-------GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGG 267
            G   PP    AGP       G P     PG+ GP   P G  +P          GPPG 
Sbjct: 600 TGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEP-GKIVPLP--------GPPGA 650

Query: 268 GGPPGTPIMPSP-GD----STNSSENMYTIMNPIGQ-GAGRANFPLGPGPEGPMAAMSAM 321
            G PG+P  P P GD     T     +      +GQ G G   FP  PGP+G       M
Sbjct: 651 EGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG---FPGPPGPKGVDGLPGDM 707

Query: 322 EPHHVNGSLGSGDMDGLP-----KSSPG-------AVAGLSNAPGTPRDDGEMAAAG 366
            P    G  G   + G P     K  PG        + GL   PGTP + G +   G
Sbjct: 708 GPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 86/293 (29%), Positives = 108/293 (36%), Gaps = 63/293 (21%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM----GPHGQPFMSPRFPGGPRPTLRMP 163
           PG   A G   +  F GP G +  P  P  P +    G  GQP +    P GP+    +P
Sbjct: 645 PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704

Query: 164 SQP-PAGLPGSQPL--LPGAMEPSPRAQ-GHPSMGGPMQRVTPPRGMASVGPQSYGGGMR 219
               P G PG      LPG   P  + Q G P +G P  +  P  G+  +       G  
Sbjct: 705 GDMGPPGTPGRPGFNGLPG--NPGVQGQKGEPGVGLPGLKGLP--GLPGIP------GTP 754

Query: 220 PPPNSLAGPGLPAMNMG---PGVRGPWASPSGNSIPYSSSSPG-------SYTGPPGGGG 269
               S+  PG+P  +     PG++G    P    +P S  SPG          GPPGG G
Sbjct: 755 GEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQG 814

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFP--LGPGPEGPMAAMSAMEPHHVN 327
           PPG  +   PG               I    G   FP    PGP+G   A        + 
Sbjct: 815 PPG--LSGPPG---------------IKGEKGFPGFPGLDMPGPKGDKGAQG------LP 851

Query: 328 GSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
           G  G   + GLP        G    PG P   GEM   GT     P +  SPG
Sbjct: 852 GITGQSGLPGLPGQQ-----GAPGIPGFPGSKGEMGVMGT-----PGQPGSPG 894



 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 78/275 (28%), Positives = 96/275 (34%), Gaps = 43/275 (15%)

Query: 124  GPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP 183
            G PG       P  P  GP G P +S   PG P            GLPG +  + G   P
Sbjct: 975  GVPGKDGQAGQPGQP--GPKGDPGISGT-PGAP------------GLPGPKGSVGGMGLP 1019

Query: 184  -SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGP 242
             +P  +G P + GP      P    + G +   G     P  +  PGL       G+ G 
Sbjct: 1020 GTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG-----PPGIGIPGLRGEKGDQGIAGF 1074

Query: 243  WASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMP-SPGDSTNSSENMYTIMNPIGQGAG 301
              SP       S   PG   G PG  G PG+   P SPG      +     ++ I    G
Sbjct: 1075 PGSPGEKGEKGSIGIPGM-PGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKG 1133

Query: 302  RANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP-------------KSSPGAVA- 347
             A  P  PGP GP           + GS G     GLP             K S G V  
Sbjct: 1134 EAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193

Query: 348  -GLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
             GL+ +PG P   GE    G      P     PG+
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGP-----PGPQGQPGL 1223



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 77/279 (27%), Positives = 99/279 (35%), Gaps = 51/279 (18%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPA 168
           GDT   G       +GPPG+   P NP  P +     P   P  PG P        + P 
Sbjct: 79  GDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGP---PGPPGIPGCNGTKGERGPL 135

Query: 169 GLPGSQPLLPGAMEPSPRAQGHPSM-GGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAG 227
           G PG    LPG    +P   G P M G P + +    GM   G + + G     P +   
Sbjct: 136 GPPG----LPG-FAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPG----IPGTPGP 186

Query: 228 PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSE 287
           PGLP      G++GP   P              +TGPPG  GPPG P            +
Sbjct: 187 PGLP------GLQGPVGPPG-------------FTGPPGPPGPPGPP--------GEKGQ 219

Query: 288 NMYTIMNPIG-QGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP----KSS 342
              +   P G +G    + P G   +  +            G  G     G+P    K  
Sbjct: 220 MGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGE 279

Query: 343 PGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPGM 381
           PG   G    PG   D GE  + G     FP E   PG+
Sbjct: 280 PGK-PGPRGKPGKDGDKGEKGSPG-----FPGEPGYPGL 312



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 84/296 (28%), Positives = 97/296 (32%), Gaps = 71/296 (23%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPG--GPRPTLRMPSQPPAGLPGSQPLLPGA 180
            QG PG       P  P  G  G P + P FPG  G    +  P QP +  P   P LPG 
Sbjct: 848  QGLPGITGQSGLPGLP--GQQGAPGI-PGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGE 904

Query: 181  M-------EPSPRAQ----------GHPSMGGPMQRVTPPRGMASVGPQSYGG------- 216
                       PR            G P   G M +V         G Q   G       
Sbjct: 905  KGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964

Query: 217  -GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPI 275
             G R  P +   PG       PG  GP   P  +  P +   PG   G  GG G PGTP 
Sbjct: 965  KGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGP-KGSVGGMGLPGTPG 1023

Query: 276  MPS-------------PGDSTNSSENMYTIMNPIGQG----------AGRANFPLGPGPE 312
                            PGD     E       P G G           G A FP  PG +
Sbjct: 1024 EKGVPGIPGPQGSPGLPGDKGAKGEKGQA--GPPGIGIPGLRGEKGDQGIAGFPGSPGEK 1081

Query: 313  GPMAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
            G              GS+G   M G P  K SPG+V G   +PG P + G+    G
Sbjct: 1082 GE------------KGSIGIPGMPGSPGLKGSPGSV-GYPGSPGLPGEKGDKGLPG 1124



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 58/176 (32%), Positives = 75/176 (42%), Gaps = 18/176 (10%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPM-MGPHGQP-FMSPRFPGGPRPTLRMPSQ 165
            PG     G      FQG PG   SP    +   MGP G P F  P+  G P        Q
Sbjct: 1274 PGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPK--GLPGLQGIKGDQ 1331

Query: 166  PPAGLPGSQ--PLLPGAMEPSPRAQGHPSMGGPMQRVTPP--RGMASV-GPQSYGG--GM 218
               G+PG++  P  PG   P    +G P + GP     PP  +G+  + GP+   G  G+
Sbjct: 1332 GDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEG---PPGLKGLQGLPGPKGQQGVTGL 1388

Query: 219  RPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP 274
               P     PG+P  +  PG +G    P+G + P     P    G PG  GPPGTP
Sbjct: 1389 VGIPGP---PGIPGFDGAPGQKGEMG-PAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 76/282 (26%), Positives = 88/282 (31%), Gaps = 67/282 (23%)

Query: 124 GPPGSQPSPHNPNAPMMGPHGQPFMS--PRFPGGPRPT-LRMPSQPPA-GLPGSQPL--- 176
           GP G +     P  P  GP G+P     P  PG P P  L +P Q  A G PG +     
Sbjct: 338 GPLGEKGERGYPGTP--GPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGD 395

Query: 177 --LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGM---RP-PPNSLAGPGL 230
              PG   P P   G   + GP     PP      G   Y  G+   +P PP     PG+
Sbjct: 396 RGFPGTSLPGP--SGRDGLPGPPGSPGPP------GQPGYTNGIVECQPGPPGDQGPPGI 447

Query: 231 PAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMY 290
           P     PG  G                   Y GPPG  GPP                   
Sbjct: 448 PGQ---PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPP------------------- 485

Query: 291 TIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLP--KSSPGAV-- 346
                     G   FP  PG +G            V G  G+  + G P  K  PG    
Sbjct: 486 ----------GEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYF 535

Query: 347 -------AGLSNAPGTPRDDGEMAAAGTFLHP-FPSESYSPG 380
                   G    PG P   G   + G   HP  P    SPG
Sbjct: 536 DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG 577



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 75/297 (25%), Positives = 98/297 (32%), Gaps = 60/297 (20%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQP- 166
           PG     G +    F GPPG    P  P     G  G  F  P+   G +     P  P 
Sbjct: 187 PGLPGLQGPVGPPGFTGPPGPPGPPGPPGEK--GQMGLSFQGPKGDKGDQGVSGPPGVPG 244

Query: 167 -----------------PAGLPGSQPLLPGAMEPS----PRAQGHPSMGGPM-QRVTP-- 202
                              G PG Q + PG  E      P  +G P   G   ++ +P  
Sbjct: 245 QAQVQEKGDFATKGEKGQKGEPGFQGM-PGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGF 303

Query: 203 ------PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGP-GVRGPWASPSGNSIPYSS 255
                 P  +   GPQ   G   PP     GP    +  GP G +G    P G   P   
Sbjct: 304 PGEPGYPGLIGRQGPQGEKGEAGPP-----GPPGIVIGTGPLGEKGERGYP-GTPGPRGE 357

Query: 256 SSPGSYTGPPGGGGPPGTPIMPS------PGDSTNSSENMYTIMNPIGQGAGRANFPLGP 309
             P  + G PG  GPPG P+         PG+     +  +   +  G  +GR   P  P
Sbjct: 358 PGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGP-SGRDGLPGPP 416

Query: 310 GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G  GP       +P + NG +         +  P    G    PG P   GE+   G
Sbjct: 417 GSPGPPG-----QPGYTNGIVEC-------QPGPPGDQGPPGIPGQPGFIGEIGEKG 461



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 66/230 (28%), Positives = 72/230 (31%), Gaps = 71/230 (30%)

Query: 115  GSMAAGFFQGPPGSQPSPHNPNAP---MMGPHGQ--PFMSPRFPGGPRPTLRMPSQPPAG 169
            GS     F GPPG Q  P  P +P     GP G   P   P  PG P P        P G
Sbjct: 1204 GSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGP------MGPPG 1257

Query: 170  LPGSQ-----------PLLPGAMEPS--PRAQGHPSMGGP------MQRVTPPRGMASVG 210
            LPG             P  PG   P   P  QG P +GG          + PP      G
Sbjct: 1258 LPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQG 1317

Query: 211  PQSYGG-----------------GMRPPPN------------SLAGP----------GLP 231
            P+   G                 G+  PP              L GP          GLP
Sbjct: 1318 PKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLP 1377

Query: 232  AMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMPSP 279
                  GV G    P    IP    +PG     GP G  GP G P  P P
Sbjct: 1378 GPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGP 1427



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 58/207 (28%), Positives = 71/207 (34%), Gaps = 53/207 (25%)

Query: 169 GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGP 228
           GLPG Q ++           G P M GP             GPQ        PP      
Sbjct: 52  GLPGLQGVI-----------GFPGMQGPE------------GPQG-------PPGQKGDT 81

Query: 229 GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSEN 288
           G P +   PG +G    P  +  P +   PG     PG  GPPG P +  PG +    E 
Sbjct: 82  GEPGL---PGTKGTRGPPGASGYPGNPGLPGI----PGQDGPPGPPGI--PGCNGTKGER 132

Query: 289 MYTIMNPIGQGAGRANFPLGPGPEG--PMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAV 346
                 P+G   G   F   PGP G   M         HV G L  G+     +  PG +
Sbjct: 133 -----GPLGP-PGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGE-----RGFPG-I 180

Query: 347 AGLSNAPGTPRDDGEMAAAGTFLHPFP 373
            G    PG P   G +   G    P P
Sbjct: 181 PGTPGPPGLPGLQGPVGPPGFTGPPGP 207



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 42/159 (26%), Positives = 50/159 (31%), Gaps = 34/159 (21%)

Query: 217 GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIM 276
           G R  P      G P M    G +GP         P    + G+  GPPG  G PG P +
Sbjct: 49  GERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGT-RGPPGASGYPGNPGL 107

Query: 277 PS-PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDM 335
           P  PG                    G    P  PG  G       + P  + G  G+   
Sbjct: 108 PGIPGQD------------------GPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGP 149

Query: 336 DGLP--KSSPGAV------------AGLSNAPGTPRDDG 360
            GLP  K  PG +             G    PGTP   G
Sbjct: 150 PGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPG 188


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 92/300 (30%), Positives = 107/300 (35%), Gaps = 52/300 (17%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQPSPHNP-NAPMMGPHGQPFM--SPRFPG--------G 155
            APG     GS  A   +G PG+   P +P  A   G  G P +  SP  PG        G
Sbjct: 1282 APGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERG 1341

Query: 156  PRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTP--PRGMASVGPQS 213
            PR     P  P   + G  P LPG  +  P   G P   GP+    P  P G+     + 
Sbjct: 1342 PRGPKGEPGAPGQVIGGEGPGLPG-RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKG 1400

Query: 214  YGG--GMRPPPNSLAG------PGLPAMNMGPGVRGPWASP-----SGNS------IPYS 254
              G  G R PP    G      PGLP +   PG +GP   P      G+S      +P  
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ 1460

Query: 255  SSSPGSY--TGPPGGGGPPGTPIMPSP-GDSTNSSENMYTIMNPIGQGAGR-----ANFP 306
              SPG     GPPG  GP G    P P G++    E       P G    R     A  P
Sbjct: 1461 PGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER-----GPPGPAGSRGLPGVAGRP 1515

Query: 307  LGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
               GPEGP        P    G  G     G P     AVAG     G     G   A G
Sbjct: 1516 GAKGPEGPPG------PTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATG 1569



 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 80/254 (31%), Positives = 94/254 (37%), Gaps = 36/254 (14%)

Query: 124  GPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAMEP 183
            GPPG + S   P   + G  G P +     G          Q P G  G   +     EP
Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLK----GAKGEPGSNGDQGPKGDRGVPGIKGDRGEP 2143

Query: 184  SPRAQ-GHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVR 240
             PR Q G+P + G        RGMA  GP+   G  G R PP  + G G P     PG+ 
Sbjct: 2144 GPRGQDGNPGLPGE-------RGMA--GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194

Query: 241  GPWASPSGNSIPYSSSSPGSYTGPPGGG--GPPGTPIMPSPGDSTNSSENMYTIMNPIGQ 298
            GP A P G S       PG  TGPPG G  GP G   +P P   +        ++ P G 
Sbjct: 2195 GP-AGPQGPS--GLKGEPGE-TGPPGRGLTGPTGAVGLPGPPGPSG-------LVGPQGS 2243

Query: 299  -----GAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNA- 352
                   G    P  PG +G            V GS G     G PK  PG       A 
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG-PKGEPGPTGAPGQAV 2302

Query: 353  PGTPRDDGEMAAAG 366
             G P   GE  A G
Sbjct: 2303 VGLPGAKGEKGAPG 2316



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 82/335 (24%), Positives = 103/335 (30%), Gaps = 75/335 (22%)

Query: 98   APSPVMGSMAPGDTMAAGSMAAGFFQGP------PGSQPSPHNPNAPMMGPHGQPFMSPR 151
            AP  V+G   PG     G        GP      PG +  P  P   M G  G      R
Sbjct: 1351 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGD--RGER 1408

Query: 152  FPGGPRPTLRMPSQP-------------PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQ 198
             P GP      P +P             P G PG +     + + +P   G P   G   
Sbjct: 1409 GPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQG 1468

Query: 199  RVTPPRGMASVGPQSYGG--------GMRPPPNSLAGPGLPAMNMGPGVRGP-------- 242
               PP  +   G + + G        G R PP      GLP +   PG +GP        
Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528

Query: 243  --------------------WASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDS 282
                                 A P G       + P   TG  G  GPPG  +   PG  
Sbjct: 1529 RQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPK 1588

Query: 283  TNSSE----NMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMD 336
             +  +     +     P G     G    P  PGP GP+       P   +G +G    +
Sbjct: 1589 GDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG------PRGRDGEVGEKGDE 1642

Query: 337  GLPKSSPG-----AVAGLSNAPGTPRDDGEMAAAG 366
            G P   PG        GL  APG     GE    G
Sbjct: 1643 G-PPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 95/337 (28%), Positives = 114/337 (33%), Gaps = 66/337 (19%)

Query: 92   DYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGP--------------PGSQPSPHNPNA 137
            D      P P  G +APG+    G   +   QGP               G+   P  P +
Sbjct: 1404 DRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGS 1463

Query: 138  P-MMGPHGQP-FMSPR----FPGGPRPTLRMPSQPPAGLPGSQPL-----LPGAMEP--- 183
            P   GP G P  + P+    FPG          + P G  GS+ L      PGA  P   
Sbjct: 1464 PGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGP 1523

Query: 184  -----------SPRAQGHPSMGGPMQRVTPPRG-MASVGPQSYGG-----GMRPPPNSLA 226
                        P   G P++ GP   V  P+G    VGP    G     G R PP  L 
Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGP--AVAGPKGEKGDVGPAGPRGATGVQGERGPP-GLV 1580

Query: 227  GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSS 286
             PG P     PG RGP    +G + P   S P    G PG  GPPG P+ P   D     
Sbjct: 1581 LPGDPGPKGDPGDRGP-IGLTGRAGPPGDSGPPGEKGDPGRPGPPG-PVGPRGRDGEVGE 1638

Query: 287  ENMYTIMNPIGQG-AGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGA 345
            +          +G  G    P   G  G   A     P    G  G    DG    SPG+
Sbjct: 1639 KG--------DEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG-RNGSPGS 1689

Query: 346  VA--GLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
                G    PG P   G +   G    P   E   PG
Sbjct: 1690 SGPKGDRGEPGPPGPPGRLVDTG----PGAREKGEPG 1722



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 92/322 (28%), Positives = 104/322 (32%), Gaps = 75/322 (23%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPG------SQPSPHNPNAPMM------GPHGQP 146
            P P      PG    AG   A   +GPPG       +  P  P  P +      GP G+ 
Sbjct: 1500 PGPAGSRGLPG---VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 147  FMSPRFPGGPR-----------PTLRMPSQP-PAGLPGSQ-PL-LPGAMEPSPRAQGHPS 192
                  P GPR           P L +P  P P G PG + P+ L G   P P   G P 
Sbjct: 1557 --GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP-PGDSGPPG 1613

Query: 193  MGGPMQRVTPPRGMASVGPQSYGG-----GMRPPPNSLAGPGLPA------MNMGPGVRG 241
              G   R  PP     VGP+   G     G   PP     PGLP       +   PGVRG
Sbjct: 1614 EKGDPGRPGPP---GPVGPRGRDGEVGEKGDEGPPGD---PGLPGKAGERGLRGAPGVRG 1667

Query: 242  PWASPSGNSIPYS--------SSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIM 293
            P         P          SS P    G PG  GPPG  +   PG             
Sbjct: 1668 PVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727

Query: 294  NPIGQGAGRANFPLGP---------GPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG 344
             P G   G    P  P         GP GP        P    G  G   +DG       
Sbjct: 1728 GPRGP-KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGR------ 1780

Query: 345  AVAGLSNAPGTPRDDGEMAAAG 366
              +GL   PG     G   AAG
Sbjct: 1781 --SGLDGKPGAAGPSGPNGAAG 1800



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 79/292 (27%), Positives = 94/292 (32%), Gaps = 36/292 (12%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
            P PV G   PG   A G       QGP G +  P     P  G  G P  +   PG P P
Sbjct: 2176 PGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTG-PTGAVGLPGPPGP 2234

Query: 159  TLRMPSQPPAGLPG-----SQPLLPG--------AMEPSPRAQGHPSMGGPMQRVTPPRG 205
            +  +  Q   GLPG      +P  PG            SP   G P + GP+     P  
Sbjct: 2235 SGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGP 2294

Query: 206  MASVGPQSYG----GGMRPPPNSLAG-----PGLPAMNMGPGVRGPWASPSGNSIPYSSS 256
              + G    G     G +  P  LAG     PG       PG RG          P    
Sbjct: 2295 TGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPG 2354

Query: 257  SPG--SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGP 314
              G     GP G  G PG  +  SPG            +  +    G   F   PG  GP
Sbjct: 2355 EDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF---PGQTGP 2411

Query: 315  MAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
               M    P    G  G    +G+P        G    PG P   G   A+G
Sbjct: 2412 RGEMGQPGPSGERGLAGPPGREGIP--------GPLGPPGPPGSVGPPGASG 2455



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 76/285 (26%), Positives = 92/285 (32%), Gaps = 30/285 (10%)

Query: 104  GSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMM-------GPHGQPFMS--PRFPG 154
            GS  P      G       QGPPG +     P    +       GP G P ++   R P 
Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027

Query: 155  GPRPTLRMPSQPPA-GLPGSQPLLPGAMEPSPRAQ-GHPSMGGPMQRVTPPRGMASVGPQ 212
            GP      P +P   GLPG    +  A  P  R + G     G   R  PP    + GP 
Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 213  SYGGGMRPPPNSL--AGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGP 270
               G    P  S+   GPGL      PG++G    P  N        P    G PG  G 
Sbjct: 2088 GPPG----PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG----DQGPKGDRGVPGIKGD 2139

Query: 271  PGTPIMPSPGDSTNSSENMYTIMNPIG----QGAGRANFPLG----PGPEGPMAAMSAME 322
             G P  P   D          +  P G    QG      P+G    PGP G         
Sbjct: 2140 RGEP-GPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 323  PHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGT 367
            P   +G  G     G P        G    PG P   G +   G+
Sbjct: 2199 PQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 78/259 (30%), Positives = 91/259 (35%), Gaps = 50/259 (19%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHG-QPFMSPRFPGGPRPTLRMPS-----QPPAGLPGSQPL 176
            +GP G +  P  P AP  G  G + F  P  P G  P +R P+     + P GL G   L
Sbjct: 1727 EGPRGPKGDPGLPGAP--GERGIEGFRGPPGPQGD-PGVRGPAGEKGDRGPPGLDGRSGL 1783

Query: 177  --LPGAMEPSPRAQGHPSMGGPMQRVTPP-RGMASVGPQSYGGGMRPPPNSLAGPGLPAM 233
               PGA  PS         G P +   P  RG   +   S   G+   P     PGL   
Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK 1843

Query: 234  NMGPGVRGPWA-----SPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSSEN 288
            N  PG  G          SG S       P    G PG  GP G P +P P         
Sbjct: 1844 NGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP--------- 1894

Query: 289  MYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAG 348
                + P GQG     FP  PG  GP             G  GS    GLP        G
Sbjct: 1895 ----VGPPGQG-----FPGVPGGTGPKGD---------RGETGSKGEQGLP-----GERG 1931

Query: 349  LSNAPGT-PRDDGEMAAAG 366
            L   PG+ P  D  +  AG
Sbjct: 1932 LRGEPGSVPNVDRLLETAG 1950



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 78/301 (25%), Positives = 95/301 (31%), Gaps = 88/301 (29%)

Query: 108  PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPP 167
            P    A   +A    Q    +QP P     P+  P GQ        G P     M  +  
Sbjct: 1220 PSLDQAVSGLATALCQASFTTQPRPEP--CPVYCPKGQK-------GEPG---EMGLRGQ 1267

Query: 168  AGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSY-GGGMRPPPNSLA 226
             G PG  P LPG    +P  QG            PP    + G + + G   RP     A
Sbjct: 1268 VGPPGD-PGLPGRTG-APGPQG------------PPGSATAKGERGFPGADGRPGSPGRA 1313

Query: 227  G----PGLPAMNMGPGVRGPWASP---------------------SGNSIPYSSSSPG-- 259
            G    PG P +   PG+ GP   P                      G  +P     PG  
Sbjct: 1314 GNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPS 1373

Query: 260  ------SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQG--------AGRANF 305
                     G PG  GPPG P     GD  +  E       P G G         G    
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGER-----GPPGPGEGGIAPGEPGLPGL 1428

Query: 306  PLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAA 365
            P  PGP+GP+       P    G  G  + DG P        GL   PG+P + G     
Sbjct: 1429 PGSPGPQGPVG------PPGKKGEKGDSE-DGAP--------GLPGQPGSPGEQGPRGPP 1473

Query: 366  G 366
            G
Sbjct: 1474 G 1474



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 73/285 (25%), Positives = 92/285 (32%), Gaps = 64/285 (22%)

Query: 123  QGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTL---RMPSQPPAGLPGSQPLLPG 179
            QGPPG  P P       +GP GQ F  P  PGG  P        S+   GLPG + L   
Sbjct: 1886 QGPPGL-PGP-------VGPPGQGF--PGVPGGTGPKGDRGETGSKGEQGLPGERGL--- 1932

Query: 180  AMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSY-------GGGMRPPPNSLAGPGLPA 232
                    +G P     + R+    G+ +   +          G   P P    GP   +
Sbjct: 1933 --------RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 233  MNMGP-GVRGPWASPSGNSIPYSSSSPGSY---------TGPPGGGG------PPGTPIM 276
               GP G  GP   P    +      PG            GPPG  G       PG P +
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 277  PS----------PGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHV 326
            P           PG+     E             G    P  PGP GP  ++    P  +
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GL 2103

Query: 327  NGSLGSGDMDGLPKSSPGA-----VAGLSNAPGTPRDDGEMAAAG 366
            +G  G   + G  K  PG+       G    PG   D GE    G
Sbjct: 2104 SGEQGPPGLKG-AKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 91/360 (25%), Positives = 113/360 (31%), Gaps = 68/360 (18%)

Query: 74   APDRREACEHSGEAKAFQDYSAAAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPH 133
            AP R  A    G+  +     +   P PV     PG T A G    G   G  G + +P 
Sbjct: 2258 APGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL-PGAKGEKGAPG 2316

Query: 134  N--------PNAP----MMGPHGQPFMSPRF--PGGPRPTLRMPSQPPAGLPGSQPLLPG 179
                     P A     + GP G+   + R   PG P    +  +  P G  G     PG
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD----PG 2372

Query: 180  AMEP-SPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMG 236
               P SP   G P + G +     P     VG     G  G    P      GL      
Sbjct: 2373 VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432

Query: 237  PGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSP-----------GDSTNS 285
             G+ GP   P     P  S  P   +G  G  G PG   +P P            D    
Sbjct: 2433 EGIPGPLGPPG----PPGSVGPPGASGLKGDKGDPGVG-LPGPRGERGEPGIRGEDGRPG 2487

Query: 286  SENMYTIMNPIGQ-----------------GAGRANFPLG-PGPEGPMAAMSAMEPHHVN 327
             E    +  P G                    G +   LG PGP G    M    P  ++
Sbjct: 2488 QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD 2547

Query: 328  GSLGSGDMDGLP-----KSSPG--AVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESYSPG 380
            G  G    +G P     K  PG    AGL    G     G+  AAG      P +  SPG
Sbjct: 2548 GDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAG-----IPGDPGSPG 2602



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 69/262 (26%), Positives = 86/262 (32%), Gaps = 32/262 (12%)

Query: 124  GPPGSQPSPHNPNAPMMGPHG-QPFMSPRFPGGPRPTLRMPSQP----PAGLPGSQPLL- 177
            GPPG  P     +    GP G      PR   G         +P     AGLPG + LL 
Sbjct: 2527 GPPG--PRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLG 2584

Query: 178  ----PGAM----EP-SPRAQGHPSMGGPMQRV--TPPRGMASVGPQSYGGGMRPPPNSLA 226
                PGA     +P SP   G P + G    V    PRG+          G+        
Sbjct: 2585 PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKG 2644

Query: 227  GPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGS--YTGPPGGGGPPGTPIMPSPGDSTN 284
              G P     PG+ G         +P  S +PG     GP G  G  G      PG   +
Sbjct: 2645 EAGPPGR---PGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDG-----QPGPKGD 2696

Query: 285  SSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPG 344
              E        IG   G +      GP GP  ++    P  + G  G     G P     
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER---GPPGERVV 2753

Query: 345  AVAGLSNAPGTPRDDGEMAAAG 366
               G+  APG   + G    AG
Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAG 2775



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 62/245 (25%), Positives = 80/245 (32%), Gaps = 54/245 (22%)

Query: 167  PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLA 226
            P G PG + L     +P P  QG P +            +   GP        P P+ LA
Sbjct: 1995 PIGFPGERGLKGDRGDPGP--QGPPGLA-----------LGERGP--------PGPSGLA 2033

Query: 227  G----PGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSY--TGPPGGGGPPGTPIMP--- 277
            G    PG+P +    G  G    P            G     GPPG  G PG P  P   
Sbjct: 2034 GEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPK 2093

Query: 278  ----SPGDSTNSSENMYTIMNPIGQ-GAGRANFPLG-------------PGPEGPMAAMS 319
                 PG   +  +    +    G+ G+     P G             PGP G      
Sbjct: 2094 VSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG 2153

Query: 320  AMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG----TFLHPFPSE 375
                  + G  G   + G P+  PG V G  + PG P   G    AG    + L   P E
Sbjct: 2154 LPGERGMAGPEGKPGLQG-PRGPPGPVGGHGD-PGPPGAPGLAGPAGPQGPSGLKGEPGE 2211

Query: 376  SYSPG 380
            +  PG
Sbjct: 2212 TGPPG 2216



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 56/198 (28%), Positives = 70/198 (35%), Gaps = 33/198 (16%)

Query: 108  PGDTMAAGSMAAGFFQGP---PGSQPSPHNPNAPMMGPHGQP----------FMSPRFPG 154
            PGD  +AG        GP   PG+   P +P +P  G  G P          FM PR   
Sbjct: 2568 PGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSP--GKDGVPGIRGEKGDVGFMGPRGLK 2625

Query: 155  GPRPTLRMPSQPPAGLPGSQPLLPGAMEPS-PRAQGHPSMGG----PMQRVTPPRGMASV 209
            G R       +   GL G +     A  P  P   GH    G    P Q   P +    +
Sbjct: 2626 GERGV-----KGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKE-GLI 2679

Query: 210  GPQSYGG-GMRPPPNSLAGP----GLPAMNMGPGVRGP--WASPSGNSIPYSSSSPGSYT 262
            GP+   G   +P P    G     G P +   PG  G    A P G         P    
Sbjct: 2680 GPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQ 2739

Query: 263  GPPGGGGPPGTPIMPSPG 280
            G  G  GPPG  ++ +PG
Sbjct: 2740 GQKGERGPPGERVVGAPG 2757


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 78/263 (29%), Positives = 88/263 (33%), Gaps = 31/263 (11%)

Query: 116 SMAAGFFQGP-PGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQ 174
           S+ AG  QGP P     P  P  P   P G P      P GP P  +    PP G     
Sbjct: 30  SLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89

Query: 175 PLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGM---RPPPNSLAGPGLP 231
           P       P  + QG P  GG   +  PP      GP   GG      PPP    GP  P
Sbjct: 90  P-----RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP-P 143

Query: 232 AMNMGPGVRGPWASP------SGNSIPYSSSSPGSYTGPPGGGG-------PPGTPIMPS 278
             +     R P   P       GN        PG   GPP  GG       PPG P  P 
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203

Query: 279 P-GDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLG---SGD 334
           P GD + SS++      P G      N P GP P  P        P   N   G    G 
Sbjct: 204 PQGDKSRSSQS--PPGKPQGPPPQGGNQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGK 259

Query: 335 MDGLPKSSPGAVAGLSNAPGTPR 357
             G P           + PG P+
Sbjct: 260 PQGPPAQGGSKSQSARSPPGKPQ 282



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 70/229 (30%), Positives = 80/229 (34%), Gaps = 28/229 (12%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P    G    G     G    G  QGPP       +P +P   P G P      P GP P
Sbjct: 54  PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 113

Query: 159 TLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGG-- 216
               P  PP    G++P  P    P  + QG P  G   +    P G    GP   GG  
Sbjct: 114 PPGKPQGPPP-QGGNRPQGP---PPPGKPQGPPPQGDKSRSPRSPPGKPQ-GPPPQGGNQ 168

Query: 217 --GMRPPPNSLAGP----GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPP--GGG 268
             G  PPP    GP    G       P  +     P G+    S S PG   GPP  GG 
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228

Query: 269 GPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPG-PEGPMA 316
            P G P  P PG              P  QG  +   P  PG P+GP A
Sbjct: 229 QPQGPP--PPPGKP----------QGPPPQGGNKPQGPPPPGKPQGPPA 265



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 58/204 (28%), Positives = 64/204 (31%), Gaps = 28/204 (13%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P    G    G     G    G  QGPP       +P +P   P G P      P GP P
Sbjct: 115 PGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP 174

Query: 159 TLRMPSQPP--AGLPGSQPLLPG--------------AMEPSPRAQGHPSMGGPMQRVTP 202
               P  PP   G     P  PG              +  P  + QG P  GG   +  P
Sbjct: 175 PPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPP 234

Query: 203 PRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYT 262
           P      GP   GG      N   GP  P    GP  +G   S S  S P     P    
Sbjct: 235 PPPGKPQGPPPQGG------NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288

Query: 263 G------PPGGGGPPGTPIMPSPG 280
           G      PP  GG P  P  P  G
Sbjct: 289 GNNPQGPPPPAGGNPQQPQAPPAG 312



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 58/198 (29%), Positives = 68/198 (34%), Gaps = 25/198 (12%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPP---GSQPSPHNPNAPMMGPHGQPFMSPRFPGG 155
           P    G    GD   +     G  QGPP   G+QP    P  P   P G P    + P G
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ--GPPPPPGKPQGPPPQGGKKPQG 192

Query: 156 PRPTLRMPSQPPAG-------LPGSQPLLP---------GAMEPSPRAQGHPSMGGPMQR 199
           P P  +    PP G        P  +P  P         G   P  + QG P  GG   +
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252

Query: 200 VTPPRGMASVGPQSYGGGMRPPPNSLAG-PGLPAMNMGPGVRGPWASPSGNSIPYSSSSP 258
             PP G    GP + GG       S  G P  P    G   +GP     GN     +   
Sbjct: 253 GPPPPGKPQ-GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA 311

Query: 259 GSYTGP--PGGGGPPGTP 274
           G   GP  P  GG P  P
Sbjct: 312 GQPQGPPRPPQGGRPSRP 329



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 57/201 (28%), Positives = 66/201 (32%), Gaps = 28/201 (13%)

Query: 173 SQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMR---PPPNSLAGPG 229
           SQ   P  +  +P  QG    GG   +  PP      GP   GG      PPP    GP 
Sbjct: 24  SQEESPSLIAGNP--QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81

Query: 230 LPAMNMGPGVRGPWASP------SGNSIPYSSSSPGSYTGPPGGGG-------PPGTPIM 276
            P  +     R P   P       GN        PG   GPP  GG       PPG P  
Sbjct: 82  -PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140

Query: 277 PSP-GDSTNSSEN-MYTIMNPIGQGAGR-------ANFPLGPGPEGPMAAMSAMEPHHVN 327
           P P GD + S  +       P  QG  +          P GP P+G         P    
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200

Query: 328 GSLGSGDMDGLPKSSPGAVAG 348
           G    GD     +S PG   G
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQG 221


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 88/303 (29%), Positives = 103/303 (33%), Gaps = 70/303 (23%)

Query: 108 PGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPT-LRMPSQP 166
           PGD    G        GPPG   SP  P     G  G+     R PG P P  +  P QP
Sbjct: 330 PGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGR-PGAPGPIGVGEPGQP 388

Query: 167 ----PAGLPGSQPLLPGAMEPSPRAQ---------------------GHPSMGGPMQRVT 201
               P G+PG + L PG   P P+ +                     G     GP   + 
Sbjct: 389 GPRGPEGVPGERGL-PGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447

Query: 202 PPRGMASVGPQSYGGGMRPP-PNSLAGPGLPAMN-----MGP---------GVRGPWASP 246
            P G+ S G Q   G + PP P   AG GLP        MGP         GV+GP   P
Sbjct: 448 IP-GIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP 506

Query: 247 SGNSIPYSSSSPG--------SYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQ 298
               +P     PG           G PG  GP G P    PG   +  +         G 
Sbjct: 507 GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK--------GS 558

Query: 299 GAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRD 358
              +    L PGPEGP       EP    G +G   M G     P    G    PG P  
Sbjct: 559 KGNQGQRGL-PGPEGPKG-----EP----GIMGPFGMPGTSIPGPPGPKGDRGGPGIPGF 608

Query: 359 DGE 361
            GE
Sbjct: 609 KGE 611



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 78/272 (28%), Positives = 91/272 (33%), Gaps = 49/272 (18%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-----MMGPHGQP----FMSPRFPGGPRPT 159
           GD    G       +G  GS P P+ P  P     + GP G P    F   +   GP   
Sbjct: 292 GDKGERGECGKPGIKGDKGS-PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGP 350

Query: 160 LRMPSQPPAGLPG-----SQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSY 214
              P  P  G  G      Q   PGA  P P   G P   GP             GP+  
Sbjct: 351 YGSPGAPGIGQQGIKGERGQEGRPGA--PGPIGVGEPGQPGPR------------GPEGV 396

Query: 215 GGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTP 274
                P    L G G P      G  GP   P G          G   GP G  GP G P
Sbjct: 397 -----PGERGLPGEGFPGPKGEKGSEGP-TGPQGLQGLSIKGEKGDI-GPVGPQGPMGIP 449

Query: 275 IMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGD 334
            + S G+          I  PIG    +   P G G  G    +  M P    G +G G 
Sbjct: 450 GIGSQGEQG--------IQGPIGPPGPQG--PAGQGLPGSKGEVGQMGPTGPRGPVGIGV 499

Query: 335 MDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
               PK  PG++ GL   PG P +DG     G
Sbjct: 500 QG--PKGEPGSI-GLPGQPGVPGEDGAAGKKG 528



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 77/271 (28%), Positives = 91/271 (33%), Gaps = 57/271 (21%)

Query: 96  AAAPSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP--MMGPHGQPFMSPRFP 153
           A  P    G   PG     G   +   QG  G  P P  P     +MGP G P  S   P
Sbjct: 535 ARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGL-PGPEGPKGEPGIMGPFGMPGTSIPGP 593

Query: 154 GGPRPTLRMPSQPPAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQS 213
            GP+     P     G+PG +       EP    +G   + GP   V  P      G + 
Sbjct: 594 PGPKGDRGGP-----GIPGFKG------EPGLSIRGPKGVQGPRGPVGAP------GLKG 636

Query: 214 YGGGMRPPPNSLAGPGLPAMNMG---------PGVRGPWASPSGNSIPYSSSSPGSYTGP 264
            G    P P  L GP  P    G         PGVRGP   PSG      +  P   TG 
Sbjct: 637 DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP-PGPSGPR-GVGTQGPKGDTGQ 694

Query: 265 PGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPH 324
            G  GPPG P   S G               I    G   F   PGP+G M        H
Sbjct: 695 KGLPGPPGPPGYGSQG---------------IKGEQGPQGF---PGPKGTMG-------H 729

Query: 325 HVNGSLGS-GDMDGLPKSSPGAVAGLSNAPG 354
            + G  G  G+   + K       G   +PG
Sbjct: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPG 760



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 41/153 (26%), Positives = 48/153 (31%), Gaps = 22/153 (14%)

Query: 178 PGAMEPSPRAQGHPSMGGPMQRVTPPRGM--ASVGPQSYGG-----GMRPPPNSLAGPGL 230
           PG   P P   G+P + G       P        G +  GG     G +        PG+
Sbjct: 247 PGDPGP-PGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGI 305

Query: 231 PAMNMGPGVRGPWA--------SPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG-D 281
                 PG  GP           P G+  P          GPPG  G PG P +   G  
Sbjct: 306 KGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIK 365

Query: 282 STNSSENMYTIMNPIGQGAGRANFPLGPGPEGP 314
                E       PIG G      P  PGP GP
Sbjct: 366 GERGQEGRPGAPGPIGVGE-----PGQPGPRGP 393



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 35/120 (29%), Positives = 41/120 (34%), Gaps = 11/120 (9%)

Query: 263 GPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQGAGRANFPLG-PGPEGPMAAMSAM 321
           G PG  GPPGT   P          N         +G      P G PG +G        
Sbjct: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQ----KGEAGERGPGGIPGYKGDKGERGEC 300

Query: 322 EPHHVNGSLGSGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAGTFLHPFPSESY-SPG 380
               + G  GS    G PK  P  + G++  PG P   G     G    P P   Y SPG
Sbjct: 301 GKPGIKGDKGSPGPYG-PK-GPRGIQGITGPPGDPGPKGFQGNKG---EPGPPGPYGSPG 355


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 79/270 (29%), Positives = 102/270 (37%), Gaps = 36/270 (13%)

Query: 124  GPPGSQPSPHNPNAPMM--GPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGS-----QPL 176
            G PG +P P  P  P    GP G P     FPG P P      +   G  G      +P 
Sbjct: 1157 GQPG-EPGPPGPKGPTGDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214

Query: 177  LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMG 236
             PG+  P P  +  P   GP+ +  P     S G Q  G G +  P ++  PG      G
Sbjct: 1215 QPGS--PGPTGENGPP--GPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPG----KTG 1265

Query: 237  P-GVRGPWASPSGNSIPYSSSSPGSY--------TGPPGGGGPPGTPIMPSPGDSTNSSE 287
            P G  GP   P  + +     S G           GPPG  GPPG P +   GD+    E
Sbjct: 1266 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR--GDAGAKGE 1323

Query: 288  N----MYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSP 343
                 +  ++ P G+   + +  L PGP+G       M     +G +G G   GLP   P
Sbjct: 1324 KGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLP--GP 1380

Query: 344  GAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                G   A G     GE    G   HP P
Sbjct: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1410



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 87/296 (29%), Positives = 103/296 (34%), Gaps = 53/296 (17%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQ--PSPHNPNAPMMGPHGQPFMSPR--FPGGPRPTLRM 162
            A G + A G+       GPPG +  P P  PN    GP G P    +   PG P     +
Sbjct: 768  ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEV 826

Query: 163  PSQPPAGLPGSQPLLPGAMEPSPRA--------QGHPSMGGPMQRVT------------- 201
              Q   G PG     PG + P   A        +GHP   GP                  
Sbjct: 827  GFQGKTGPPGP----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 882

Query: 202  --PPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSS 257
              PP      GP    G  G R  P +  GPGL   N GP   GP   P+G+     ++ 
Sbjct: 883  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG-NEGPS--GP-PGPAGSPGERGAAG 938

Query: 258  PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGAGRANFPLG-PGPEGPM 315
             G   GPPG  GP G P   + G+     E       PIG  G      P+G PGP GP 
Sbjct: 939  SGGPIGPPGRPGPQGPP--GAAGEKGVPGEK-----GPIGPTGRDGVQGPVGLPGPAGPP 991

Query: 316  AAMSAMEPHHVNGSLGSGDMDGL-----PKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                        G  G     G      P   PG + G    PG    DGE  A G
Sbjct: 992  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1046



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 73/265 (27%), Positives = 97/265 (36%), Gaps = 37/265 (13%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMS--PRFPG--GPRPTLRMP 163
           G+    GS      +GP G      +P  P +MG  G+  +   P +PG  GP+ +L  P
Sbjct: 671 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 730

Query: 164 SQPPA-GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRP-- 220
             P A G  G++ L   + +  PR +  P+  GP  +  P       G +   GG  P  
Sbjct: 731 GFPGASGEKGARGL---SGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 785

Query: 221 PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
           PP     PG    N  PG +GP   P  + +P      G   G  G  GPPG P +  P 
Sbjct: 786 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE-VGFQGKTGPPGPPGVVGP- 843

Query: 281 DSTNSSENMYTIMNPIGQGAGRANFPLG----PGPEGPMAAMSAMEPHHVNGSLGSGDMD 336
                            QGA     P+G    PGP GP             G+ G     
Sbjct: 844 -----------------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886

Query: 337 GLP-KSSPGAVAGLSNAPGTPRDDG 360
           G P K  P  + G     G P   G
Sbjct: 887 GAPGKDGPAGLRGFPGERGLPGTAG 911



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 82/280 (29%), Positives = 100/280 (35%), Gaps = 38/280 (13%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P P+  +  PG     GS       G  G Q  P  P   + GP G+     R   G   
Sbjct: 403 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ-GPRGPQG-LTGPPGKAGRRGR--AGADG 458

Query: 159 TLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRVTPP-----RGM-ASVG 210
              MP  P  G+ G +    LPG     P  +GH    G      PP     RG    +G
Sbjct: 459 ARGMPGDP--GVKGDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 512

Query: 211 PQSYGGGMRPPPNSLAGP-GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG 269
           P+   G     P  L GP G P +   PGVRG    P G   P  S  P    GPPG  G
Sbjct: 513 PRGLPG--ESGPRGLLGPKGPPGIPGPPGVRG-MDGPQG---PKGSLGPQGEPGPPGQQG 566

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PGT  +P P  +          + P G+    G+   P  PG +GP        P    
Sbjct: 567 TPGTQGLPGPQGA----------IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 616

Query: 328 GSLG-SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G+ G SG    L    P  V G+    G     GE    G
Sbjct: 617 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 656



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 71/279 (25%), Positives = 91/279 (32%), Gaps = 43/279 (15%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQ-PFMSPRFPGGPR--------PTLRMPSQPPAGLPGS 173
           Q P  +Q SP    + +  P  Q P      PG           P L   +  P GL G 
Sbjct: 239 QQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGE 298

Query: 174 QPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPP-----PNSLAGP 228
           +   P  +EP    +G P   GP   + PP    + GP    G   PP     P S   P
Sbjct: 299 KGE-PAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP 357

Query: 229 GLPAMNM--------GPGVRGPWAS----------PSGNSIPYSSSSPGSYTGPPGGGGP 270
           G P  ++        G G +GP  +                      P  YTG PG  G 
Sbjct: 358 GPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQ 417

Query: 271 PGTP-IMPSPGD-STNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNG 328
           PG+P +    GD           +  P G+   R       G  G   A        V G
Sbjct: 418 PGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR-------GRAGADGARGMPGDPGVKG 470

Query: 329 SLGSGDMDGLP-KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
             G   + GLP +       G    PG P +DGE    G
Sbjct: 471 DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG 509



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 84/293 (28%), Positives = 101/293 (34%), Gaps = 53/293 (18%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
            +PG+  AAGS   G   GPPG +P P  P     G  G P    + P GP  T R   Q 
Sbjct: 930  SPGERGAAGS---GGPIGPPG-RPGPQGPPGAA-GEKGVP--GEKGPIGP--TGRDGVQG 980

Query: 167  PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVT--------PPRGMASVGPQSYGG-- 216
            P GLPG  P  P  +      +G   +G P Q+ T        PP     +GP    G  
Sbjct: 981  PVGLPG--PAGPPGVAGEDGDKGE--VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1036

Query: 217  ------GMRPPPNSLAGPGLPAMNMGPGVRGPWA-----SPSGNSIPYSSSSPGSYTGPP 265
                  G R P       G        G  GP        PSG         P    GPP
Sbjct: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1096

Query: 266  GGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQ-----GAGRANFPLGPGPEGPMAAMSA 320
            G  GP G    P+  D           + P G+      +G       PG +GP      
Sbjct: 1097 GPRGPAG----PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1152

Query: 321  MEPHHVNGSLG-------SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                   G  G       +GD DG PK +PG V G    PG P + G     G
Sbjct: 1153 KGESGQPGEPGPPGPKGPTGD-DG-PKGNPGPV-GFPGDPGPPGEGGPRGQDG 1202



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 69/233 (29%), Positives = 79/233 (33%), Gaps = 54/233 (23%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-----MMGPHGQPFMS---- 149
            P P       G   A G        G PGS P P   N P       GP G P       
Sbjct: 1189 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGS-PGPTGENGPPGPLGKRGPAGSPGSEGRQG 1247

Query: 150  -------PRFPGGPRPTLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRV 200
                   P   G P  T  +    PAG PG   L  LPG++    R  G     GP   V
Sbjct: 1248 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPV 1306

Query: 201  TPP-----RGMASV-GPQSYGG--GMRPPPNSLAGPG---LPAMNMGPGVRG----PWAS 245
             PP     RG A   G + + G  G+  PP      G   LP     PG +G    P AS
Sbjct: 1307 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1366

Query: 246  -------------PSGNSIPYSSSSPGS------YTGPPGGGGPPGTPIMPSP 279
                         P+G      ++ PG         GPPG  GPPG  I P P
Sbjct: 1367 GPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1419


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 79/270 (29%), Positives = 102/270 (37%), Gaps = 36/270 (13%)

Query: 124  GPPGSQPSPHNPNAPMM--GPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGS-----QPL 176
            G PG +P P  P  P    GP G P     FPG P P      +   G  G      +P 
Sbjct: 1136 GQPG-EPGPPGPKGPTGDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193

Query: 177  LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMG 236
             PG+  P P  +  P   GP+ +  P     S G Q  G G +  P ++  PG      G
Sbjct: 1194 QPGS--PGPTGENGPP--GPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPG----KTG 1244

Query: 237  P-GVRGPWASPSGNSIPYSSSSPGSY--------TGPPGGGGPPGTPIMPSPGDSTNSSE 287
            P G  GP   P  + +     S G           GPPG  GPPG P +   GD+    E
Sbjct: 1245 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR--GDAGAKGE 1302

Query: 288  N----MYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSP 343
                 +  ++ P G+   + +  L PGP+G       M     +G +G G   GLP   P
Sbjct: 1303 KGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLP--GP 1359

Query: 344  GAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                G   A G     GE    G   HP P
Sbjct: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1389



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 87/296 (29%), Positives = 103/296 (34%), Gaps = 53/296 (17%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQ--PSPHNPNAPMMGPHGQPFMSPR--FPGGPRPTLRM 162
            A G + A G+       GPPG +  P P  PN    GP G P    +   PG P     +
Sbjct: 747  ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEV 805

Query: 163  PSQPPAGLPGSQPLLPGAMEPSPRA--------QGHPSMGGPMQRVT------------- 201
              Q   G PG     PG + P   A        +GHP   GP                  
Sbjct: 806  GFQGKTGPPGP----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 861

Query: 202  --PPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSS 257
              PP      GP    G  G R  P +  GPGL   N GP   GP   P+G+     ++ 
Sbjct: 862  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG-NEGPS--GP-PGPAGSPGERGAAG 917

Query: 258  PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGAGRANFPLG-PGPEGPM 315
             G   GPPG  GP G P   + G+     E       PIG  G      P+G PGP GP 
Sbjct: 918  SGGPIGPPGRPGPQGPP--GAAGEKGVPGEK-----GPIGPTGRDGVQGPVGLPGPAGPP 970

Query: 316  AAMSAMEPHHVNGSLGSGDMDGL-----PKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                        G  G     G      P   PG + G    PG    DGE  A G
Sbjct: 971  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1025



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 73/265 (27%), Positives = 97/265 (36%), Gaps = 37/265 (13%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMS--PRFPG--GPRPTLRMP 163
           G+    GS      +GP G      +P  P +MG  G+  +   P +PG  GP+ +L  P
Sbjct: 650 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 709

Query: 164 SQPPA-GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRP-- 220
             P A G  G++ L   + +  PR +  P+  GP  +  P       G +   GG  P  
Sbjct: 710 GFPGASGEKGARGL---SGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 764

Query: 221 PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
           PP     PG    N  PG +GP   P  + +P      G   G  G  GPPG P +  P 
Sbjct: 765 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE-VGFQGKTGPPGPPGVVGP- 822

Query: 281 DSTNSSENMYTIMNPIGQGAGRANFPLG----PGPEGPMAAMSAMEPHHVNGSLGSGDMD 336
                            QGA     P+G    PGP GP             G+ G     
Sbjct: 823 -----------------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865

Query: 337 GLP-KSSPGAVAGLSNAPGTPRDDG 360
           G P K  P  + G     G P   G
Sbjct: 866 GAPGKDGPAGLRGFPGERGLPGTAG 890



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 82/280 (29%), Positives = 100/280 (35%), Gaps = 38/280 (13%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P P+  +  PG     GS       G  G Q  P  P   + GP G+     R   G   
Sbjct: 382 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ-GPRGPQG-LTGPPGKAGRRGR--AGADG 437

Query: 159 TLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRVTPP-----RGM-ASVG 210
              MP  P  G+ G +    LPG     P  +GH    G      PP     RG    +G
Sbjct: 438 ARGMPGDP--GVKGDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 491

Query: 211 PQSYGGGMRPPPNSLAGP-GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG 269
           P+   G     P  L GP G P +   PGVRG    P G   P  S  P    GPPG  G
Sbjct: 492 PRGLPG--ESGPRGLLGPKGPPGIPGPPGVRG-MDGPQG---PKGSLGPQGEPGPPGQQG 545

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PGT  +P P  +          + P G+    G+   P  PG +GP        P    
Sbjct: 546 TPGTQGLPGPQGA----------IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 595

Query: 328 GSLG-SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G+ G SG    L    P  V G+    G     GE    G
Sbjct: 596 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 635



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 68/270 (25%), Positives = 89/270 (32%), Gaps = 36/270 (13%)

Query: 123 QGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGSQPLLPGAME 182
           +G    +P    P+     P  QP    R P    P  +  +  P GL G +   P  +E
Sbjct: 229 EGGQRERPQNQQPHRAQRSPQQQPSRLHR-PQNQEPQSQA-AHGPRGLKGEKGE-PAVLE 285

Query: 183 PSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPP-----PNSLAGPGLPAMNM-- 235
           P    +G P   GP   + PP    + GP    G   PP     P S   PG P  ++  
Sbjct: 286 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLML 345

Query: 236 ------GPGVRGPWAS----------PSGNSIPYSSSSPGSYTGPPGGGGPPGTP-IMPS 278
                 G G +GP  +                      P  YTG PG  G PG+P +   
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 405

Query: 279 PGD-STNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDG 337
            GD           +  P G+   R       G  G   A        V G  G   + G
Sbjct: 406 SGDLGPQGPRGPQGLTGPPGKAGRR-------GRAGADGARGMPGDPGVKGDRGFDGLPG 458

Query: 338 LP-KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           LP +       G    PG P +DGE    G
Sbjct: 459 LPGEKGHRGDTGAQGLPGPPGEDGERGDDG 488



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 84/293 (28%), Positives = 101/293 (34%), Gaps = 53/293 (18%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
            +PG+  AAGS   G   GPPG +P P  P     G  G P    + P GP  T R   Q 
Sbjct: 909  SPGERGAAGS---GGPIGPPG-RPGPQGPPGAA-GEKGVP--GEKGPIGP--TGRDGVQG 959

Query: 167  PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVT--------PPRGMASVGPQSYGG-- 216
            P GLPG  P  P  +      +G   +G P Q+ T        PP     +GP    G  
Sbjct: 960  PVGLPG--PAGPPGVAGEDGDKGE--VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1015

Query: 217  ------GMRPPPNSLAGPGLPAMNMGPGVRGPWA-----SPSGNSIPYSSSSPGSYTGPP 265
                  G R P       G        G  GP        PSG         P    GPP
Sbjct: 1016 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1075

Query: 266  GGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQ-----GAGRANFPLGPGPEGPMAAMSA 320
            G  GP G    P+  D           + P G+      +G       PG +GP      
Sbjct: 1076 GPRGPAG----PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131

Query: 321  MEPHHVNGSLG-------SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                   G  G       +GD DG PK +PG V G    PG P + G     G
Sbjct: 1132 KGESGQPGEPGPPGPKGPTGD-DG-PKGNPGPV-GFPGDPGPPGEGGPRGQDG 1181



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 69/233 (29%), Positives = 79/233 (33%), Gaps = 54/233 (23%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-----MMGPHGQPFMS---- 149
            P P       G   A G        G PGS P P   N P       GP G P       
Sbjct: 1168 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGS-PGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226

Query: 150  -------PRFPGGPRPTLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRV 200
                   P   G P  T  +    PAG PG   L  LPG++    R  G     GP   V
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPV 1285

Query: 201  TPP-----RGMASV-GPQSYGG--GMRPPPNSLAGPG---LPAMNMGPGVRG----PWAS 245
             PP     RG A   G + + G  G+  PP      G   LP     PG +G    P AS
Sbjct: 1286 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1345

Query: 246  -------------PSGNSIPYSSSSPGS------YTGPPGGGGPPGTPIMPSP 279
                         P+G      ++ PG         GPPG  GPPG  I P P
Sbjct: 1346 GPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1398


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 79/270 (29%), Positives = 102/270 (37%), Gaps = 36/270 (13%)

Query: 124  GPPGSQPSPHNPNAPMM--GPHGQPFMSPRFPGGPRPTLRMPSQPPAGLPGS-----QPL 176
            G PG +P P  P  P    GP G P     FPG P P      +   G  G      +P 
Sbjct: 1243 GQPG-EPGPPGPKGPTGDDGPKGNPG-PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300

Query: 177  LPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPPPNSLAGPGLPAMNMG 236
             PG+  P P  +  P   GP+ +  P     S G Q  G G +  P ++  PG      G
Sbjct: 1301 QPGS--PGPTGENGPP--GPLGKRGPAGSPGSEGRQG-GKGAKGDPGAIGAPG----KTG 1351

Query: 237  P-GVRGPWASPSGNSIPYSSSSPGSY--------TGPPGGGGPPGTPIMPSPGDSTNSSE 287
            P G  GP   P  + +     S G           GPPG  GPPG P +   GD+    E
Sbjct: 1352 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR--GDAGAKGE 1409

Query: 288  N----MYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAMEPHHVNGSLGSGDMDGLPKSSP 343
                 +  ++ P G+   + +  L PGP+G       M     +G +G G   GLP   P
Sbjct: 1410 KGHPGLIGLIGPPGEQGEKGDRGL-PGPQGSPGQKGEMGIPGASGPIGPGGPPGLP--GP 1466

Query: 344  GAVAGLSNAPGTPRDDGEMAAAGTFLHPFP 373
                G   A G     GE    G   HP P
Sbjct: 1467 AGPKGAKGATGPGGPKGEKGVQGPPGHPGP 1496



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 87/296 (29%), Positives = 103/296 (34%), Gaps = 53/296 (17%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQ--PSPHNPNAPMMGPHGQPFMSPR--FPGGPRPTLRM 162
            A G + A G+       GPPG +  P P  PN    GP G P    +   PG P     +
Sbjct: 854  ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEV 912

Query: 163  PSQPPAGLPGSQPLLPGAMEPSPRA--------QGHPSMGGPMQRVT------------- 201
              Q   G PG     PG + P   A        +GHP   GP                  
Sbjct: 913  GFQGKTGPPGP----PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD 968

Query: 202  --PPRGMASVGPQSYGG--GMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSS 257
              PP      GP    G  G R  P +  GPGL   N GP   GP   P+G+     ++ 
Sbjct: 969  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKG-NEGPS--GP-PGPAGSPGERGAAG 1024

Query: 258  PGSYTGPPGGGGPPGTPIMPSPGDSTNSSENMYTIMNPIG-QGAGRANFPLG-PGPEGPM 315
             G   GPPG  GP G P   + G+     E       PIG  G      P+G PGP GP 
Sbjct: 1025 SGGPIGPPGRPGPQGPP--GAAGEKGVPGEK-----GPIGPTGRDGVQGPVGLPGPAGPP 1077

Query: 316  AAMSAMEPHHVNGSLGSGDMDGL-----PKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                        G  G     G      P   PG + G    PG    DGE  A G
Sbjct: 1078 GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPGARG 1132



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 73/265 (27%), Positives = 97/265 (36%), Gaps = 37/265 (13%)

Query: 109 GDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-MMGPHGQPFMS--PRFPG--GPRPTLRMP 163
           G+    GS      +GP G      +P  P +MG  G+  +   P +PG  GP+ +L  P
Sbjct: 757 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFP 816

Query: 164 SQPPA-GLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRP-- 220
             P A G  G++ L   + +  PR +  P+  GP  +  P       G +   GG  P  
Sbjct: 817 GFPGASGEKGARGL---SGKSGPRGERGPT--GPRGQRGPRGATGKSGAKGTSGGDGPHG 871

Query: 221 PPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPG 280
           PP     PG    N  PG +GP   P  + +P      G   G  G  GPPG P +  P 
Sbjct: 872 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE-VGFQGKTGPPGPPGVVGP- 929

Query: 281 DSTNSSENMYTIMNPIGQGAGRANFPLG----PGPEGPMAAMSAMEPHHVNGSLGSGDMD 336
                            QGA     P+G    PGP GP             G+ G     
Sbjct: 930 -----------------QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972

Query: 337 GLP-KSSPGAVAGLSNAPGTPRDDG 360
           G P K  P  + G     G P   G
Sbjct: 973 GAPGKDGPAGLRGFPGERGLPGTAG 997



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 82/280 (29%), Positives = 100/280 (35%), Gaps = 38/280 (13%)

Query: 99  PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRP 158
           P P+  +  PG     GS       G  G Q  P  P   + GP G+     R   G   
Sbjct: 489 PGPMGYTGRPGPLGQPGSPGLKGESGDLGPQ-GPRGPQG-LTGPPGKAGRRGR--AGADG 544

Query: 159 TLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRVTPP-----RGM-ASVG 210
              MP  P  G+ G +    LPG     P  +GH    G      PP     RG    +G
Sbjct: 545 ARGMPGDP--GVKGDRGFDGLPGL----PGEKGHRGDTGAQGLPGPPGEDGERGDDGEIG 598

Query: 211 PQSYGGGMRPPPNSLAGP-GLPAMNMGPGVRGPWASPSGNSIPYSSSSPGSYTGPPGGGG 269
           P+   G     P  L GP G P +   PGVRG    P G   P  S  P    GPPG  G
Sbjct: 599 PRGLPG--ESGPRGLLGPKGPPGIPGPPGVRG-MDGPQG---PKGSLGPQGEPGPPGQQG 652

Query: 270 PPGTPIMPSPGDSTNSSENMYTIMNPIGQGA--GRANFPLGPGPEGPMAAMSAMEPHHVN 327
            PGT  +P P  +          + P G+    G+   P  PG +GP        P    
Sbjct: 653 TPGTQGLPGPQGA----------IGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTK 702

Query: 328 GSLG-SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
           G+ G SG    L    P  V G+    G     GE    G
Sbjct: 703 GNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDG 742



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 84/293 (28%), Positives = 101/293 (34%), Gaps = 53/293 (18%)

Query: 107  APGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHGQPFMSPRFPGGPRPTLRMPSQP 166
            +PG+  AAGS   G   GPPG +P P  P     G  G P    + P GP  T R   Q 
Sbjct: 1016 SPGERGAAGS---GGPIGPPG-RPGPQGPPGAA-GEKGVP--GEKGPIGP--TGRDGVQG 1066

Query: 167  PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVT--------PPRGMASVGPQSYGG-- 216
            P GLPG  P  P  +      +G   +G P Q+ T        PP     +GP    G  
Sbjct: 1067 PVGLPG--PAGPPGVAGEDGDKGE--VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAA 1122

Query: 217  ------GMRPPPNSLAGPGLPAMNMGPGVRGPWA-----SPSGNSIPYSSSSPGSYTGPP 265
                  G R P       G        G  GP        PSG         P    GPP
Sbjct: 1123 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPP 1182

Query: 266  GGGGPPGTPIMPSPGDSTNSSENMYTIMNPIGQ-----GAGRANFPLGPGPEGPMAAMSA 320
            G  GP G    P+  D           + P G+      +G       PG +GP      
Sbjct: 1183 GPRGPAG----PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1238

Query: 321  MEPHHVNGSLG-------SGDMDGLPKSSPGAVAGLSNAPGTPRDDGEMAAAG 366
                   G  G       +GD DG PK +PG V G    PG P + G     G
Sbjct: 1239 KGESGQPGEPGPPGPKGPTGD-DG-PKGNPGPV-GFPGDPGPPGEGGPRGQDG 1288



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 59/226 (26%), Positives = 75/226 (33%), Gaps = 34/226 (15%)

Query: 167 PAGLPGSQPLLPGAMEPSPRAQGHPSMGGPMQRVTPPRGMASVGPQSYGGGMRPP----- 221
           P GL G +   P  +EP    +G P   GP   + PP    + GP    G   PP     
Sbjct: 378 PRGLKGEKGE-PAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436

Query: 222 PNSLAGPGLPAMNM--------GPGVRGPWAS----------PSGNSIPYSSSSPGSYTG 263
           P S   PG P  ++        G G +GP  +                      P  YTG
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTG 496

Query: 264 PPGGGGPPGTP-IMPSPGD-STNSSENMYTIMNPIGQGAGRANFPLGPGPEGPMAAMSAM 321
            PG  G PG+P +    GD           +  P G+   R       G  G   A    
Sbjct: 497 RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR-------GRAGADGARGMP 549

Query: 322 EPHHVNGSLGSGDMDGLP-KSSPGAVAGLSNAPGTPRDDGEMAAAG 366
               V G  G   + GLP +       G    PG P +DGE    G
Sbjct: 550 GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDG 595



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 69/233 (29%), Positives = 79/233 (33%), Gaps = 54/233 (23%)

Query: 99   PSPVMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAP-----MMGPHGQPFMS---- 149
            P P       G   A G        G PGS P P   N P       GP G P       
Sbjct: 1275 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGS-PGPTGENGPPGPLGKRGPAGSPGSEGRQG 1333

Query: 150  -------PRFPGGPRPTLRMPSQPPAGLPGSQPL--LPGAMEPSPRAQGHPSMGGPMQRV 200
                   P   G P  T  +    PAG PG   L  LPG++    R  G     GP   V
Sbjct: 1334 GKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRP-GATGQAGPPGPV 1392

Query: 201  TPP-----RGMASV-GPQSYGG--GMRPPPNSLAGPG---LPAMNMGPGVRG----PWAS 245
             PP     RG A   G + + G  G+  PP      G   LP     PG +G    P AS
Sbjct: 1393 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1452

Query: 246  -------------PSGNSIPYSSSSPGS------YTGPPGGGGPPGTPIMPSP 279
                         P+G      ++ PG         GPPG  GPPG  I P P
Sbjct: 1453 GPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLP 1505


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,772,983
Number of Sequences: 37866
Number of extensions: 1843105
Number of successful extensions: 19142
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 302
Number of HSP's successfully gapped in prelim test: 1566
Number of HSP's that attempted gapping in prelim test: 7663
Number of HSP's gapped (non-prelim): 5738
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press