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Search of human proteins with 89213250
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89213250 intermediate filament family orphan isoform 4 [Homo
sapiens]
(563 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89213250 intermediate filament family orphan isoform 4 [Homo ... 1122 0.0
gi|18490978 intermediate filament family orphan isoform 2 [Homo ... 1105 0.0
gi|210147457 intermediate filament family orphan 2 [Homo sapiens] 535 e-152
gi|89213247 intermediate filament family orphan isoform 3 [Homo ... 402 e-112
gi|62414289 vimentin [Homo sapiens] 82 2e-15
gi|28173564 keratin 73 [Homo sapiens] 82 2e-15
gi|15618995 keratin 71 [Homo sapiens] 79 8e-15
gi|89357932 keratin 5b [Homo sapiens] 76 9e-14
gi|153791158 keratin 75 [Homo sapiens] 75 2e-13
gi|4504919 keratin 8 [Homo sapiens] 74 3e-13
gi|148612803 keratin 6 irs4 [Homo sapiens] 74 3e-13
gi|119395754 keratin 5 [Homo sapiens] 70 4e-12
gi|109148552 keratin 3 [Homo sapiens] 70 4e-12
gi|109255249 keratin 4 [Homo sapiens] 70 7e-12
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 70 7e-12
gi|28372503 keratin 72 isoform 1 [Homo sapiens] 69 9e-12
gi|226246663 keratin 72 isoform 1 [Homo sapiens] 69 9e-12
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 3e-11
gi|155969697 keratin 6C [Homo sapiens] 67 4e-11
gi|5031839 keratin 6A [Homo sapiens] 67 6e-11
gi|67782365 keratin 7 [Homo sapiens] 66 7e-11
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap... 66 1e-10
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens] 66 1e-10
gi|55749932 desmin [Homo sapiens] 65 1e-10
gi|119395750 keratin 1 [Homo sapiens] 65 2e-10
gi|153791670 keratin 76 [Homo sapiens] 65 2e-10
gi|119703753 keratin 6B [Homo sapiens] 65 2e-10
gi|21264345 peripherin [Homo sapiens] 63 8e-10
gi|47132620 keratin 2 [Homo sapiens] 62 1e-09
gi|125628636 keratin 80 isoform a [Homo sapiens] 61 3e-09
>gi|89213250 intermediate filament family orphan isoform 4 [Homo
sapiens]
Length = 563
Score = 1122 bits (2902), Expect = 0.0
Identities = 563/563 (100%), Positives = 563/563 (100%)
Query: 1 MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP 60
MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP
Sbjct: 1 MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP 60
Query: 61 PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG 120
PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG
Sbjct: 61 PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG 120
Query: 121 RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS 180
RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS
Sbjct: 121 RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS 180
Query: 181 TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA 240
TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA
Sbjct: 181 TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA 240
Query: 241 LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE 300
LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE
Sbjct: 241 LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE 300
Query: 301 LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKL 360
LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKL
Sbjct: 301 LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKL 360
Query: 361 VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED 420
VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED
Sbjct: 361 VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED 420
Query: 421 DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQET 480
DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQET
Sbjct: 421 DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQET 480
Query: 481 IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS 540
IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS
Sbjct: 481 IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS 540
Query: 541 DPPPPPSEAEDSDRDVSSDSSMR 563
DPPPPPSEAEDSDRDVSSDSSMR
Sbjct: 541 DPPPPPSEAEDSDRDVSSDSSMR 563
>gi|18490978 intermediate filament family orphan isoform 2 [Homo
sapiens]
Length = 559
Score = 1105 bits (2857), Expect = 0.0
Identities = 559/563 (99%), Positives = 559/563 (99%), Gaps = 4/563 (0%)
Query: 1 MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP 60
MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP
Sbjct: 1 MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAP 60
Query: 61 PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG 120
PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG
Sbjct: 61 PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLG 120
Query: 121 RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS 180
RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS
Sbjct: 121 RRDQAVQTGFVSPIRPLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTS 180
Query: 181 TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA 240
TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA
Sbjct: 181 TSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRA 240
Query: 241 LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE 300
LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE
Sbjct: 241 LYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE 300
Query: 301 LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKL 360
LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQ
Sbjct: 301 LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQ--- 357
Query: 361 VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED 420
VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED
Sbjct: 358 VPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFED 417
Query: 421 DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQET 480
DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGE QEDSLEKVIKDTESLFKTREKEYQET
Sbjct: 418 DCDSLTWEETEETLLLWEDFSGYAMAAAEAQGE-QEDSLEKVIKDTESLFKTREKEYQET 476
Query: 481 IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS 540
IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS
Sbjct: 477 IDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLS 536
Query: 541 DPPPPPSEAEDSDRDVSSDSSMR 563
DPPPPPSEAEDSDRDVSSDSSMR
Sbjct: 537 DPPPPPSEAEDSDRDVSSDSSMR 559
>gi|210147457 intermediate filament family orphan 2 [Homo sapiens]
Length = 517
Score = 535 bits (1378), Expect = e-152
Identities = 314/541 (58%), Positives = 373/541 (68%), Gaps = 41/541 (7%)
Query: 19 LAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAMALRNDLGSNINVLK 78
L G + + G GGG P G GPGP+P A ALR+DLGSNI++LK
Sbjct: 6 LFGEMALAFGCPPGGGGGGCP------GGGGGGGGAGPGPSPVTA-ALRDDLGSNIHLLK 58
Query: 79 TLNLRFRCFLAKVHELERRNRLLEKQL-QQALEEGKQGRRGLGRRDQAVQTG--FVSPIR 135
LN+RFRCFLAKVHELERRNRLLEKQL QQ E ++ R R+QAVQTG + P
Sbjct: 59 GLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPA 118
Query: 136 PLGLQLGARPAAVCSPSARVLGSPARSPAGPLAPSAASLSSSSTSTSTTYSSSARFMPGT 195
P G L S A + A A + L S Y +PGT
Sbjct: 119 PGG--------------GHGLSSGAAAGANANAVALGGLPPGGGSHPQHYGR----LPGT 160
Query: 196 IWSFSHARRLGPGLEPTLVQGPGLSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEY 255
IWS++ RR G G T VQGPG+SWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEY
Sbjct: 161 IWSYTQVRRTGGGGVET-VQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEY 219
Query: 256 KRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAELVVFKGLMSNNLSEL 315
KRRWEEE R+ LQ V+ LQE AQEADA QEE+ K+E+LKAELVVFKGLMS+ +++L
Sbjct: 220 KRRWEEELAKRMNLQTMVDTLQEAAQEADAIQEEMNEKIERLKAELVVFKGLMSDPMTDL 279
Query: 316 DTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKLVPSMGGRKRERKAAV 375
DTKIQEKAMKVDMDICRRIDITAKLCDVAQQRN ED+ ++FQ +VP +K+ERK A
Sbjct: 280 DTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ--VVP----KKKERKVAS 333
Query: 376 EEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLRE-YDFEDDCDSLTWEETEETL 434
++D S + E R D +E +++I +EM+RM NQLRE +DF+DDCDSLTWEE E+TL
Sbjct: 334 DDDISEQDGEVNRFSD---DEVGSMNITDEMKRMFNQLRETFDFDDDCDSLTWEENEDTL 390
Query: 435 LLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKND 494
LLWEDF+ + QGE QE++L +I +TES FKTR+KEYQETI QIELELATAK+D
Sbjct: 391 LLWEDFTN-CNPTIDLQGE-QEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSD 448
Query: 495 MNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPPPPPSEAEDSDR 554
MNRHLHEYMEMCSMKRGLDVQMETCRRLI S DR SP+ ++V SD ++ +R
Sbjct: 449 MNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDEFER 508
Query: 555 D 555
+
Sbjct: 509 E 509
>gi|89213247 intermediate filament family orphan isoform 3 [Homo
sapiens]
Length = 200
Score = 402 bits (1033), Expect = e-112
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 364 MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 423
MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD
Sbjct: 1 MGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCD 60
Query: 424 SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 483
SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ
Sbjct: 61 SLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQ 120
Query: 484 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 543
IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP
Sbjct: 121 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTAVPLSDPP 180
Query: 544 PPPSEAEDSDRDVSSDSSMR 563
PPPSEAEDSDRDVSSDSSMR
Sbjct: 181 PPPSEAEDSDRDVSSDSSMR 200
>gi|62414289 vimentin [Homo sapiens]
Length = 466
Score = 81.6 bits (200), Expect = 2e-15
Identities = 75/321 (23%), Positives = 139/321 (43%), Gaps = 71/321 (22%)
Query: 237 EIRALYNVLAKVKRERDEY-------KRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
++ L N A+V+ ERD + + +EE R + ++ + +++ A + +
Sbjct: 160 QVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLARLD 219
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQ--- 346
L KVE L+ E+ K L + EL +IQE+ +++D+D+ + D+TA L DV QQ
Sbjct: 220 LERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQIDVDVSKP-DLTAALRDVRQQYES 278
Query: 347 ---RNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSIN 403
+N ++ + ++ K R A + ++EST
Sbjct: 279 VAAKNLQEAEEWYKSKFADLSEAANRNNDALRQA----------------KQEST----- 317
Query: 404 EEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVI 463
E +R + L C+ + T E+L E Q + E++
Sbjct: 318 -EYRRQVQSL-------TCEVDALKGTNESL--------------ERQMREMEEN----- 350
Query: 464 KDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
F YQ+TI +++ E+ K +M RHL EY ++ ++K LD+++ T R+L+
Sbjct: 351 ------FAVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLL 404
Query: 524 TQSGDRKS---PAFTAVPLSD 541
R S P F+++ L +
Sbjct: 405 EGEESRISLPLPNFSSLNLRE 425
Score = 30.8 bits (68), Expect = 3.5
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 77 LKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGK 113
L+ LN RF ++ KV LE++N++L +L+Q +GK
Sbjct: 107 LQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGK 143
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 81.6 bits (200), Expect = 2e-15
Identities = 73/306 (23%), Positives = 135/306 (44%), Gaps = 48/306 (15%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q++T++ + L + L V+ ++YK+R+EEE R ++ L+++ A + E
Sbjct: 193 QLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVE 252
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ FK L +++ + I + ++ + MD R +D+ + + +V Q
Sbjct: 253 LQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQ--Y 310
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ RK + +A T E + GD+ + T I+ E+ R+
Sbjct: 311 EEI-------------ARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIS-ELTRL 356
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR E E ++Q +LE I D E
Sbjct: 357 IQRLR-------------SEIESV-------------------KKQCANLETAIADAEQR 384
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR 529
K+ + +D++E L AK ++ R L EY E+ S+K LD+++ T R+L+ R
Sbjct: 385 GDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECR 444
Query: 530 KSPAFT 535
S +T
Sbjct: 445 MSGEYT 450
Score = 30.0 bits (66), Expect = 5.9
Identities = 29/134 (21%), Positives = 60/134 (44%), Gaps = 18/134 (13%)
Query: 229 VQIDTITPEIRALYNVLAKVKRERDE--YKRRWEEEYTVRIQLQDRVNELQEEAQEADAC 286
+ +D+I E+RA Y +A+ + E Y+ +++E + D + + E E
Sbjct: 297 LDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRL 356
Query: 287 QEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDV--A 344
+ L ++E +K + + L+T I + + D C D AKL ++ A
Sbjct: 357 IQRLRSEIESVKKQ-----------CANLETAIADAEQRGD---CALKDARAKLDELEGA 402
Query: 345 QQRNCEDMIQMFQK 358
Q+ E++ +M ++
Sbjct: 403 LQQAKEELARMLRE 416
>gi|15618995 keratin 71 [Homo sapiens]
Length = 523
Score = 79.3 bits (194), Expect = 8e-15
Identities = 72/305 (23%), Positives = 139/305 (45%), Gaps = 48/305 (15%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q++T++ + L + L V+ ++YK+R+EEE R ++ L+++ A A + E
Sbjct: 191 QLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVE 250
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KVE + E+ F+ L ++++ + I + ++ + MD R +D+ + + +V Q
Sbjct: 251 LQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQ--- 307
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
+++ + S K E +A + T E + GD+ ++T I+ E+ R+
Sbjct: 308 ------YEEIALKS----KAEAEALYQ--TKFQELQLAAGRHGDDLKNTKNEIS-ELTRL 354
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ ++R E E ++Q +LE I D E
Sbjct: 355 IQRIR-------------SEIENV-------------------KKQASNLETAIADAEQR 382
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR 529
K+ + +D++E L AK ++ R L EY E+ S+K LD+++ T R+L+ R
Sbjct: 383 GDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECR 442
Query: 530 KSPAF 534
S F
Sbjct: 443 MSGEF 447
>gi|89357932 keratin 5b [Homo sapiens]
Length = 520
Score = 75.9 bits (185), Expect = 9e-14
Identities = 75/315 (23%), Positives = 131/315 (41%), Gaps = 54/315 (17%)
Query: 225 DGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEAD 284
D + Q++ + E AL L + + +EYK ++EEE R L++ L+++
Sbjct: 167 DQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVF 226
Query: 285 ACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVA 344
+ EL K+E L+ L K L L +L T+ + ++ + MD R +D ++ + +V
Sbjct: 227 LSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEV- 285
Query: 345 QQRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSI-- 402
+ E++ R + +A T E + Q GD + T + I
Sbjct: 286 -RARYEEI-------------ARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQ 331
Query: 403 -NEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEK 461
++E+QR+ +Q ++Q SL+
Sbjct: 332 LHQEIQRLQSQTENL------------------------------------KKQNASLQA 355
Query: 462 VIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRR 521
I D E + K+ Q +D++E L AK ++ R L EY E+ S K LDV++ T RR
Sbjct: 356 AITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRR 415
Query: 522 LITQSGDRKSPAFTA 536
L+ R S T+
Sbjct: 416 LLEGEECRMSGECTS 430
>gi|153791158 keratin 75 [Homo sapiens]
Length = 551
Score = 75.1 bits (183), Expect = 2e-13
Identities = 77/316 (24%), Positives = 136/316 (43%), Gaps = 53/316 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+++IT E L L ++ +++K R+E+E R ++ L+++ A + E
Sbjct: 210 QLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVE 269
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ + LS+L T++ + ++ + MD R +D+ + + +V Q
Sbjct: 270 LEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQY-- 327
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
ED+ + +A T E + GD+ +T I+E M RM
Sbjct: 328 EDI-------------ANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISE-MNRM 373
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + DS+ ++Q SL+ I D E
Sbjct: 374 IQRLRA-----EIDSV---------------------------KKQCSSLQTAIADAEQR 401
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI-----T 524
+ K+ + + +E L AK DM R L EY E+ ++K LDV++ T R+L+
Sbjct: 402 GELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECR 461
Query: 525 QSGDRKSPAFTAVPLS 540
SG+ SP +V S
Sbjct: 462 LSGEGVSPVNISVVTS 477
Score = 32.3 bits (72), Expect = 1.2
Identities = 15/38 (39%), Positives = 25/38 (65%)
Query: 77 LKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQ 114
+KTLN +F F+ KV LE++N++LE + E+G +
Sbjct: 153 IKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSR 190
>gi|4504919 keratin 8 [Homo sapiens]
Length = 483
Score = 74.3 bits (181), Expect = 3e-13
Identities = 65/295 (22%), Positives = 130/295 (44%), Gaps = 50/295 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q++T+ E L L ++ +++K ++E+E R ++++ ++++ EA + E
Sbjct: 150 QLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVE 209
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L ++E L E+ + L + EL ++I + ++ + MD R +D+ + + +V Q
Sbjct: 210 LESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQY-- 267
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
ED+ + S +E+E Q +E +S A ++++R
Sbjct: 268 EDIA------------------------NRSRAEAESMYQIKYEELQSLAGKHGDDLRRT 303
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQG-EQQEDSLEKVIKDTES 468
++ E + + AE +G + Q SLE I D E
Sbjct: 304 KTEISEMN-----------------------RNISRLQAEIEGLKGQRASLEAAIADAEQ 340
Query: 469 LFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + ++E L AK DM R L EY E+ ++K LD+++ T R+L+
Sbjct: 341 RGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLL 395
Score = 30.8 bits (68), Expect = 3.5
Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 77 LKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGL 119
+KTLN +F F+ KV LE++N++LE + L++ K R +
Sbjct: 95 IKTLNNKFASFIDKVRFLEQQNKMLETK-WSLLQQQKTARSNM 136
>gi|148612803 keratin 6 irs4 [Homo sapiens]
Length = 529
Score = 74.3 bits (181), Expect = 3e-13
Identities = 68/294 (23%), Positives = 131/294 (44%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q++T++ + L + L ++ ++YK+R+E E R ++ L+++A A A + E
Sbjct: 201 QLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVE 260
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ K L ++++ T E ++ + MD R +D+ + + +V
Sbjct: 261 LQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEV------ 314
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
+M +++ K + +A T + E + GD+ + T S E+ R+
Sbjct: 315 ----RMHYEEI-----ALKSKAEAEALYQTKIQELQLAASRHGDDLKHTR-SEMVELNRL 364
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ ++R C+ ++Q SLE I D E
Sbjct: 365 IQRIR-------CEI-------------------------GNVKKQRASLETAIADAEQR 392
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
K+ Q +D++E L AK ++ R L EY E+ S+K LD+++ T R+L+
Sbjct: 393 GDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLL 446
>gi|119395754 keratin 5 [Homo sapiens]
Length = 590
Score = 70.5 bits (171), Expect = 4e-12
Identities = 68/294 (23%), Positives = 126/294 (42%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+D+I E L + L ++ +++K ++E+E R ++ L+++ A + E
Sbjct: 229 QLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVE 288
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ K LS++ T + + ++ + MD R +D+ + + +V Q
Sbjct: 289 LEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQ--- 345
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
+ R R +A T E + GD+ +T I+ EM RM
Sbjct: 346 -----------YEEIANRSR-TEAESWYQTKYEELQQTAGRHGDDLRNTKHEIS-EMNRM 392
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + D++ ++Q +L+ I D E
Sbjct: 393 IQRLRA-----EIDNV---------------------------KKQCANLQNAIADAEQR 420
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + + ++E L AK DM R L EY E+ + K LDV++ T R+L+
Sbjct: 421 GELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLL 474
Score = 33.5 bits (75), Expect = 0.53
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Query: 28 GGDHFAGGGDLPPAPLSPAGPA-------AYSPPGPGPAPPAAMALRNDLGSNINVLKTL 80
GG F GG P P+ P G + P P+ +R + I KTL
Sbjct: 119 GGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQI---KTL 175
Query: 81 NLRFRCFLAKVHELERRNRLLEKQLQQALEEG 112
N +F F+ KV LE++N++L+ + E+G
Sbjct: 176 NNKFASFIDKVRFLEQQNKVLDTKWTLLQEQG 207
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 70.5 bits (171), Expect = 4e-12
Identities = 66/294 (22%), Positives = 130/294 (44%), Gaps = 50/294 (17%)
Query: 231 IDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEEL 290
+D I E L + L ++ +++K+++E+E R ++ L+++ A + EL
Sbjct: 262 LDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVEL 321
Query: 291 ALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCE 350
KV+ L E+ + L LS++ + I + ++ + MD R +D+ + + +V Q E
Sbjct: 322 QAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRAQ--YE 379
Query: 351 DMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRML 410
D+ Q + + +A T L E + GD+ +T I E+ RM+
Sbjct: 380 DIAQ-------------RSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEI-IELNRMI 425
Query: 411 NQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQG-EQQEDSLEKVIKDTESL 469
+LR AE +G ++Q +L+ I + E
Sbjct: 426 QRLR---------------------------------AEIEGVKKQNANLQTAIAEAEQH 452
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + +++ L AK+D+ R L +Y E+ ++K LDV++ T R+L+
Sbjct: 453 GEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLL 506
>gi|109255249 keratin 4 [Homo sapiens]
Length = 594
Score = 69.7 bits (169), Expect = 7e-12
Identities = 70/298 (23%), Positives = 132/298 (44%), Gaps = 56/298 (18%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+DT+ + L + L ++ +++K ++EEE R ++ L+++ A + E
Sbjct: 272 QLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVE 331
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ K L LS++ T + + ++ + MD R +D+ + + +V Q
Sbjct: 332 LEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQ--Y 389
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ Q + + +A T + + + GD ++T I E+ RM
Sbjct: 390 EEIAQ-------------RSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEI-AELNRM 435
Query: 410 LNQLRE--YDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTE 467
+ +LR + + C +L ++A AE +G E +KD
Sbjct: 436 IQRLRAEIENIKKQCQTLQ----------------VSVADAEQRG-------ENALKDAH 472
Query: 468 SLFKTREKEYQETIDQIELE--LATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
S ++ELE L AK ++ R L EY E+ S+K LD+++ T R+L+
Sbjct: 473 S-------------KRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLL 517
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 69.7 bits (169), Expect = 7e-12
Identities = 69/303 (22%), Positives = 129/303 (42%), Gaps = 51/303 (16%)
Query: 235 TPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKV 294
T E +AL ++ + R+EEE R + R+ E ++ A EA + EL ++
Sbjct: 154 TNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRI 213
Query: 295 EQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQ 354
+ L E+ K + ++EL +IQ + V+MD+ + D++A L D+ Q
Sbjct: 214 DSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKP-DLSAALKDIRAQ-------- 264
Query: 355 MFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLR 414
++K +M + K+ T L+ES + + +E+ L+
Sbjct: 265 -YEKLAAKNMQNAEEWFKSRF---TVLTESAA-------KNTDAVRAAKDEVSESRRLLK 313
Query: 415 EYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTRE 474
E + A E +LEK +++ E
Sbjct: 314 AKTLE-------------------------IEACRGMNE----ALEKQLQELEDKQNADI 344
Query: 475 KEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAF 534
Q+TI+++E EL T K++M R+L EY ++ ++K LD+++ R+L+ G+ +F
Sbjct: 345 SAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLL--EGEETRLSF 402
Query: 535 TAV 537
T+V
Sbjct: 403 TSV 405
Score = 35.4 bits (80), Expect = 0.14
Identities = 20/45 (44%), Positives = 29/45 (64%), Gaps = 4/45 (8%)
Query: 65 ALRNDLGS----NINVLKTLNLRFRCFLAKVHELERRNRLLEKQL 105
A+ NDL S L+ LN RF F+ +VHELE++N++LE +L
Sbjct: 78 AISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAEL 122
>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 69.3 bits (168), Expect = 9e-12
Identities = 68/306 (22%), Positives = 133/306 (43%), Gaps = 58/306 (18%)
Query: 226 GVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADA 285
G GV++D+ E+R + +++ ++YK+R+E E R ++ L+++ A
Sbjct: 192 GDGVRLDS---ELRNMQDLV-------EDYKKRYEVEINRRTAAENEFVVLKKDVDAAYM 241
Query: 286 CQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQ 345
+ EL KV+ L E+ FK L ++++ + I + ++ + MD R +D+ + + +V
Sbjct: 242 NKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRA 301
Query: 346 QRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEE 405
Q E++ K + +A T + E + GD+ + T I+ E
Sbjct: 302 Q--YEEI-------------ALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEIS-E 345
Query: 406 MQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKD 465
+ R++ ++R + ++Q LE I D
Sbjct: 346 LNRLIQRIR--------------------------------SEIGNVKKQCADLETAIAD 373
Query: 466 TESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQ 525
E K+ + +D++E L AK ++ R L EY E+ S+K LD+++ T R+L+
Sbjct: 374 AEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLES 433
Query: 526 SGDRKS 531
R S
Sbjct: 434 EECRMS 439
>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
Length = 511
Score = 69.3 bits (168), Expect = 9e-12
Identities = 68/306 (22%), Positives = 133/306 (43%), Gaps = 58/306 (18%)
Query: 226 GVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADA 285
G GV++D+ E+R + +++ ++YK+R+E E R ++ L+++ A
Sbjct: 192 GDGVRLDS---ELRNMQDLV-------EDYKKRYEVEINRRTAAENEFVVLKKDVDAAYM 241
Query: 286 CQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQ 345
+ EL KV+ L E+ FK L ++++ + I + ++ + MD R +D+ + + +V
Sbjct: 242 NKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRA 301
Query: 346 QRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEE 405
Q E++ K + +A T + E + GD+ + T I+ E
Sbjct: 302 Q--YEEI-------------ALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEIS-E 345
Query: 406 MQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKD 465
+ R++ ++R + ++Q LE I D
Sbjct: 346 LNRLIQRIR--------------------------------SEIGNVKKQCADLETAIAD 373
Query: 466 TESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQ 525
E K+ + +D++E L AK ++ R L EY E+ S+K LD+++ T R+L+
Sbjct: 374 AEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLES 433
Query: 526 SGDRKS 531
R S
Sbjct: 434 EECRMS 439
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.4 bits (163), Expect = 3e-11
Identities = 72/329 (21%), Positives = 124/329 (37%), Gaps = 70/329 (21%)
Query: 232 DTITPEIRALYNVLAKVKRERDEY--------------KRRWEEEYTVRIQLQDRVNELQ 277
D EIR L L V E+ + K R+EEE +R + + L+
Sbjct: 148 DAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALR 207
Query: 278 EEAQEADACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDIT 337
++ +EA + EL KV+ L+ E+ + +++L +IQ + V+ + DI+
Sbjct: 208 KDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDIS 267
Query: 338 AKLCDVAQQRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEES 397
L ++ Q M Q + K + T +E
Sbjct: 268 TALKEIRSQLESHSDQNMHQAE---------EWFKCRYAKLTEAAEQN------------ 306
Query: 398 TALSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQED 457
E ++ ++ EY + S+ E T ++
Sbjct: 307 -----KEAIRSAKEEIAEYRRQLQSKSIELESVRGT----------------------KE 339
Query: 458 SLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQME 517
SLE+ + D E YQ+TI Q+E EL K +M RHL EY ++ ++K LD+++
Sbjct: 340 SLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIA 399
Query: 518 TCRRLI--------TQSGDRKSPAFTAVP 538
R+L+ T +G P +T P
Sbjct: 400 AYRKLLEGEETRFSTFAGSITGPLYTHRP 428
Score = 30.8 bits (68), Expect = 3.5
Identities = 39/174 (22%), Positives = 70/174 (40%), Gaps = 29/174 (16%)
Query: 318 KIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKLVPSMGGRKRERKAAVEE 377
K++ +KV I K+ D ++ E+ + ++L SM K E+K A EE
Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVED--EKSEMEEALTAITEELAVSM---KEEKKEAAEE 494
Query: 378 DTSLSESEGPRQPDGDEEE---------STALSINEEMQRMLNQLREYDFEDDCDSLTWE 428
+P+ +EEE +TA + EE + + + E++ + +
Sbjct: 495 KEE--------EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546
Query: 429 ETEETLLLWEDFSGY-------AMAAAEAQGEQQEDSLEKVIKDTESLFKTREK 475
+ EE E S AEA+GE+ E EK +++ T+E+
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600
>gi|155969697 keratin 6C [Homo sapiens]
Length = 564
Score = 67.0 bits (162), Expect = 4e-11
Identities = 67/294 (22%), Positives = 126/294 (42%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+D+I E L + L ++ ++ K ++E+E R ++ L+++ A + E
Sbjct: 224 QLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVE 283
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L K + L E+ + L LS++ T I + ++ + MD R +D+ + + +V Q
Sbjct: 284 LQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ--Y 341
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ Q + +A T E + GD+ +T I E+ RM
Sbjct: 342 EEIAQ-------------RSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEI-AEINRM 387
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + D + ++Q SL+ I D E
Sbjct: 388 IQRLR-----SEIDHV---------------------------KKQCASLQAAIADAEQR 415
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + ++ +E L AK D+ R L EY E+ ++K LDV++ T R+L+
Sbjct: 416 GEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469
Score = 34.3 bits (77), Expect = 0.31
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
Query: 28 GGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAM----ALRNDLGSNINVLKTLNLR 83
GG AGG P P+ P G P + A++ +KTLN +
Sbjct: 114 GGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNK 173
Query: 84 FRCFLAKVHELERRNRLLEKQLQQALEEG 112
F F+ KV LE++N++L+ + E+G
Sbjct: 174 FASFIDKVRFLEQQNKVLDTKWTLLQEQG 202
>gi|5031839 keratin 6A [Homo sapiens]
Length = 564
Score = 66.6 bits (161), Expect = 6e-11
Identities = 66/294 (22%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+D+I E L + L ++ +++K ++E+E R ++ L+++ A + E
Sbjct: 224 QLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVE 283
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L K + L E+ + L LS++ T I + ++ + MD R +D+ + + +V Q
Sbjct: 284 LQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ--Y 341
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ Q + +A T E + GD+ +T I E+ RM
Sbjct: 342 EEIAQ-------------RSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEI-AEINRM 387
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + D + ++Q +L+ I D E
Sbjct: 388 IQRLR-----SEIDHV---------------------------KKQCANLQAAIADAEQR 415
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + ++ +E L AK D+ R L EY E+ ++K LDV++ T R+L+
Sbjct: 416 GEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469
Score = 33.9 bits (76), Expect = 0.41
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
Query: 28 GGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAMALRNDL----GSNINVLKTLNLR 83
GG AGG P P+ P G P + + + +KTLN +
Sbjct: 114 GGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNK 173
Query: 84 FRCFLAKVHELERRNRLLEKQLQQALEEG 112
F F+ KV LE++N++LE + E+G
Sbjct: 174 FASFIDKVRFLEQQNKVLETKWTLLQEQG 202
>gi|67782365 keratin 7 [Homo sapiens]
Length = 469
Score = 66.2 bits (160), Expect = 7e-11
Identities = 64/297 (21%), Positives = 126/297 (42%), Gaps = 57/297 (19%)
Query: 229 VQID--TITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADAC 286
+Q+D + E+R++ +V+ +++K ++E+E R ++ L+++ A
Sbjct: 155 LQVDGGRLEAELRSMQDVV-------EDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
Query: 287 QEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQ 346
+ EL KV+ L E+ + L L+EL ++I + ++ + MD R +D+ + +V Q
Sbjct: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
Query: 347 RNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEM 406
E+M + +A T + GD+ +T I+ EM
Sbjct: 268 --YEEM-------------AKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEIS-EM 311
Query: 407 QRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDT 466
R + +L + + D++ + Q LE I +
Sbjct: 312 NRAIQRL-----QAEIDNI---------------------------KNQRAKLEAAIAEA 339
Query: 467 ESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
E + K+ + +++E L K DM R L EY E+ S+K LD+++ T R+L+
Sbjct: 340 EERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLL 396
Score = 32.7 bits (73), Expect = 0.91
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 5/60 (8%)
Query: 59 APPAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLEKQ--LQQALEEGKQGR 116
A P+ +R + I KTLN +F F+ KV LE++N+LLE + L Q + K R
Sbjct: 80 ADPSLQRVRQEESEQI---KTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSR 136
>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
sapiens]
Length = 431
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/291 (21%), Positives = 129/291 (44%), Gaps = 56/291 (19%)
Query: 246 AKVKRERDEY-------KRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLK 298
A+++ ERD +++ ++E +R++ ++ + ++EA EA + +L K+E L+
Sbjct: 135 ARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLE 194
Query: 299 AELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQK 358
E+ + + + EL ++ + + V++D+ + D+TA L ++ Q M +
Sbjct: 195 EEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKP-DLTAALKEIRTQYEAMASSNMHEA 253
Query: 359 KLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDF 418
+ K A D + +E RQ + + +R L L
Sbjct: 254 E-------EWYRSKFADLTDAAARNAELLRQAKHEAND---------YRRQLQSLT---- 293
Query: 419 EDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQ 478
CD + T E+L E Q +QE E+ +++ S YQ
Sbjct: 294 ---CDLESLRGTNESL--------------ERQMREQE---ERHVREAAS--------YQ 325
Query: 479 ETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR 529
E + ++E E + K++M RHL EY ++ ++K LD+++ T R+L+ +R
Sbjct: 326 EALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENR 376
>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
Length = 432
Score = 65.9 bits (159), Expect = 1e-10
Identities = 64/291 (21%), Positives = 129/291 (44%), Gaps = 56/291 (19%)
Query: 246 AKVKRERDEY-------KRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLK 298
A+++ ERD +++ ++E +R++ ++ + ++EA EA + +L K+E L+
Sbjct: 135 ARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLE 194
Query: 299 AELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQK 358
E+ + + + EL ++ + + V++D+ + D+TA L ++ Q M +
Sbjct: 195 EEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKP-DLTAALKEIRTQYEAMASSNMHEA 253
Query: 359 KLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDF 418
+ K A D + +E RQ + + +R L L
Sbjct: 254 E-------EWYRSKFADLTDAAARNAELLRQAKHEAND---------YRRQLQSLT---- 293
Query: 419 EDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQ 478
CD + T E+L E Q +QE E+ +++ S YQ
Sbjct: 294 ---CDLESLRGTNESL--------------ERQMREQE---ERHVREAAS--------YQ 325
Query: 479 ETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR 529
E + ++E E + K++M RHL EY ++ ++K LD+++ T R+L+ +R
Sbjct: 326 EALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENR 376
>gi|55749932 desmin [Homo sapiens]
Length = 470
Score = 65.5 bits (158), Expect = 1e-10
Identities = 91/396 (22%), Positives = 171/396 (43%), Gaps = 40/396 (10%)
Query: 156 LGSPARSPAGPLAPSAASLSSSSTSTSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLV- 214
LGSP SP P A + SSSS ++ S G + S A RLG P+
Sbjct: 26 LGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSL-RASRLGTTRTPSSYG 84
Query: 215 QGPGLSWVHPDGVGVQIDTITP----EIRAL----YNVLAKVKRERDEYKRRWEEEYTVR 266
G L + D V + T E++ L N + KV+ + E ++
Sbjct: 85 AGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLK 144
Query: 267 IQLQDRVNELQEEAQEADACQEELALKVEQL---KAELVVFKGLMSNNLSELDTKIQEK- 322
+ RV EL EE EL +VE L +A + V + + ++L L K+QE+
Sbjct: 145 GREPTRVAELYEEE------LRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEI 198
Query: 323 -----------AMKVDMDIC--RRIDITAKLCDVAQQRNCEDMIQMFQKKLVPSMGGRKR 369
A + D+D RID+ ++ + ++ ++ ++ + + + +
Sbjct: 199 QLKEEAENNLAAFRADVDAATLARIDLERRIESLNEE---IAFLKKVHEEEIRELQAQLQ 255
Query: 370 ERKAAVEEDTSLSE-SEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCDSLTWE 428
E++ VE D S + + R E A +I+E + +++ + + ++
Sbjct: 256 EQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALR 315
Query: 429 ETEETLLLW-EDFSGYAMAAAEAQGEQQEDSLEKVIKDTESLFKTREKEYQETIDQIELE 487
+ ++ ++ + Y +G DSL + +++ E F + YQ+ I ++E E
Sbjct: 316 QAKQEMMEYRHQIQSYTCEIDALKG--TNDSLMRQMRELEDRFASEASGYQDNIARLEEE 373
Query: 488 LATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K++M RHL EY ++ ++K LDV++ T R+L+
Sbjct: 374 IRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLL 409
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 65.1 bits (157), Expect = 2e-10
Identities = 61/302 (20%), Positives = 131/302 (43%), Gaps = 48/302 (15%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
++D + + L + L ++ ++Y+ ++E+E R ++ ++++ A + +
Sbjct: 241 RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD 300
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L K++ L+ E+ L LS++ T+I E + + MD R +D+ + + +V Q
Sbjct: 301 LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQ--Y 358
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
ED+ Q K + +A + E + GD ++ + I+ E+ R+
Sbjct: 359 EDIAQ-------------KSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEIS-ELNRV 404
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + D++ ++Q +L++ I D E
Sbjct: 405 IQRLR-----SEIDNV---------------------------KKQISNLQQSISDAEQR 432
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR 529
+ K+ + ++ +E L AK D+ R L +Y E+ + K LD+++ T R L+ R
Sbjct: 433 GENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESR 492
Query: 530 KS 531
S
Sbjct: 493 MS 494
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 65.1 bits (157), Expect = 2e-10
Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+D++ E L L ++ +++K+++E+E R ++ L+++ A + E
Sbjct: 244 QLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVE 303
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L KV+ L E+ + L LS++ + + ++ + MD R +D+ + + +V Q
Sbjct: 304 LQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQ--Y 361
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ Q + + +A T L E + GD+ +T I E+ RM
Sbjct: 362 EEIAQ-------------RSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEI-MELNRM 407
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR E E ++Q +L+ I + E
Sbjct: 408 IQRLR-------------AEIENV-------------------KKQNANLQTAIAEAEQR 435
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + ++ L AK+D+ R L +Y E+ ++K LDV++ T R+L+
Sbjct: 436 GEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLL 489
>gi|119703753 keratin 6B [Homo sapiens]
Length = 564
Score = 65.1 bits (157), Expect = 2e-10
Identities = 66/294 (22%), Positives = 125/294 (42%), Gaps = 48/294 (16%)
Query: 230 QIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEE 289
Q+D I E L + L ++ ++ K ++E+E R ++ L+++ A + E
Sbjct: 224 QLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVE 283
Query: 290 LALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNC 349
L K + L E+ + L LS++ T I + ++ + MD R +D+ + + +V Q
Sbjct: 284 LQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQ--Y 341
Query: 350 EDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRM 409
E++ Q + +A T E + GD+ +T I E+ RM
Sbjct: 342 EEIAQ-------------RSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEI-AEINRM 387
Query: 410 LNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIKDTESL 469
+ +LR + D + ++Q +L+ I D E
Sbjct: 388 IQRLR-----SEIDHV---------------------------KKQCANLQAAIADAEQR 415
Query: 470 FKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI 523
+ K+ + ++ +E L AK D+ R L EY E+ ++K LDV++ T R+L+
Sbjct: 416 GEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469
Score = 34.3 bits (77), Expect = 0.31
Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
Query: 28 GGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAM----ALRNDLGSNINVLKTLNLR 83
GG AGG P P+ P G P + A++ +KTLN +
Sbjct: 114 GGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNK 173
Query: 84 FRCFLAKVHELERRNRLLEKQLQQALEEG 112
F F+ KV LE++N++L+ + E+G
Sbjct: 174 FASFIDKVRFLEQQNKVLDTKWTLLQEQG 202
>gi|21264345 peripherin [Homo sapiens]
Length = 470
Score = 62.8 bits (151), Expect = 8e-10
Identities = 72/337 (21%), Positives = 126/337 (37%), Gaps = 84/337 (24%)
Query: 237 EIRALYNVLAKVKRERDEY--------------KRRWEEEYTVRIQLQDRVNELQEEAQE 282
E+R L L + RERD K+R EEE R + + +++ +
Sbjct: 147 ELRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDD 206
Query: 283 ADACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQ-EKAMKVDMDICRRIDITAKLC 341
A + EL K+E L E+ K L L +L ++ ++ +V+++ + ++TA L
Sbjct: 207 ATLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALR 266
Query: 342 DVAQQ------RNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEE 395
D+ Q +N ++ + ++ K R +A + ++ES
Sbjct: 267 DIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNES----------- 315
Query: 396 ESTALSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQ 455
+R + L C+ T E LL
Sbjct: 316 -----------RRQIQSLT-------CEVDGLRGTNEALL-------------------- 337
Query: 456 EDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQ 515
+ +++ E F YQ ++E EL K +M RHL EY E+ ++K LD++
Sbjct: 338 -----RQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKMALDIE 392
Query: 516 METCRRLITQSGDRKSPAF---------TAVPLSDPP 543
+ T R+L+ R S T VP +PP
Sbjct: 393 IATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPP 429
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 62.0 bits (149), Expect = 1e-09
Identities = 65/321 (20%), Positives = 134/321 (41%), Gaps = 53/321 (16%)
Query: 225 DGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEAD 284
D + +D +T E + + L ++ ++YK+++E+E R ++ L+++ A
Sbjct: 234 DSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAY 293
Query: 285 ACQEELALKVEQLKAELVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVA 344
+ EL KV+ L E+ K L +S++ + + + + MD R +D+ + + +V
Sbjct: 294 MIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVK 353
Query: 345 QQRNCEDMIQMFQKKLVPSMGGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINE 404
Q E++ Q +++ + E + V GD + + I+
Sbjct: 354 AQ--YEEIAQRSKEEAEALYHSKYEELQVTVGR-------------HGDSLKEIKIEIS- 397
Query: 405 EMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGEQQEDSLEKVIK 464
E+ R++ +L+ A ++Q +++ I
Sbjct: 398 ELNRVIQRLQ--------------------------------GEIAHVKKQCKNVQDAIA 425
Query: 465 DTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLI- 523
D E + K+ + ++ +E L AK D+ R L +Y E+ ++K LDV++ T R+L+
Sbjct: 426 DAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLE 485
Query: 524 ----TQSGDRKSPAFTAVPLS 540
SGD S +V S
Sbjct: 486 GEECRMSGDLSSNVTVSVTSS 506
>gi|125628636 keratin 80 isoform a [Homo sapiens]
Length = 452
Score = 60.8 bits (146), Expect = 3e-09
Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 51/295 (17%)
Query: 245 LAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAELVVF 304
L +V + +E++ R+E+E + R ++ +L+++ + EL K++ L++ + +
Sbjct: 157 LLQVLEKVEEFRIRYEDEISKRTDMEFTFVQLKKDLDAECLHRTELETKLKSLESFVELM 216
Query: 305 KGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQKKLVPSM 364
K + L +L ++++ ++ V MD ID++ + +V Q + S+
Sbjct: 217 KTIYEQELKDLAAQVKDVSVTVGMDSRCHIDLSGIVEEVKAQ---------YDAVAARSL 267
Query: 365 GGRKRERKAAVEEDTSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCDS 424
+ ++ +EE + S G S +N +Q++ +Q+ + C
Sbjct: 268 EEAEAYSRSQLEEQAARSAEYGSSL---QSSRSEIADLNVRIQKLRSQI--LSVKSHC-- 320
Query: 425 LTWEETEETLLLWEDFSGYAMAAAEAQGEQQ-EDSLEKVIKDTESLFKTREKEYQETIDQ 483
L EE +T AE QGE +D+ K+ Q
Sbjct: 321 LKLEENIKT--------------AEEQGELAFQDAKTKLA-------------------Q 347
Query: 484 IELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLIT-QSGDRKSPAFTAV 537
+E L AK DM R L +Y E+ ++K LD+++ T R+L+ + G SP+ T V
Sbjct: 348 LEAALQQAKQDMARQLRKYQELMNVKLALDIEIATYRKLVEGEEGRMDSPSATVV 402
Score = 30.4 bits (67), Expect = 4.5
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 61 PAAMALRNDLGSNINVLKTLNLRFRCFLAKVHELERRNRLLE 102
PA L+N +K LN +F + KV LE+RN+LLE
Sbjct: 74 PAVQQLKNQEKEE---MKALNDKFASLIGKVQALEQRNQLLE 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,524,597
Number of Sequences: 37866
Number of extensions: 1332567
Number of successful extensions: 16612
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 547
Number of HSP's that attempted gapping in prelim test: 13530
Number of HSP's gapped (non-prelim): 3260
length of query: 563
length of database: 18,247,518
effective HSP length: 107
effective length of query: 456
effective length of database: 14,195,856
effective search space: 6473310336
effective search space used: 6473310336
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.