Search of human proteins with 7710145

Search of human proteins with 7710145

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
         (302 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7710145 methyl-CpG binding domain protein 2 testis-specific i...   647   0.0  
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s...   495   e-140
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]         132   5e-31
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ...    86   5e-17
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s...    86   5e-17
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho...    86   5e-17
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ...    86   5e-17
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo...    86   5e-17
gi|109452587 family with sequence similarity 98, member B isofor...    75   5e-14
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]     73   4e-13
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]       73   4e-13
gi|55956899 keratin 9 [Homo sapiens]                                   69   4e-12
gi|47132620 keratin 2 [Homo sapiens]                                   67   1e-11
gi|195972866 keratin 10 [Homo sapiens]                                 66   3e-11
gi|109255251 loricrin [Homo sapiens]                                   66   3e-11
gi|119395750 keratin 1 [Homo sapiens]                                  66   4e-11
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 66   4e-11
gi|109148552 keratin 3 [Homo sapiens]                                  65   1e-10
gi|12056465 fibrillarin [Homo sapiens]                                 62   5e-10
gi|28875797 small protein rich in arginine and glycine [Homo sap...    62   8e-10
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]           58   9e-09
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]          58   9e-09
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    57   2e-08
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor...    57   2e-08
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform...    57   2e-08
gi|153791670 keratin 76 [Homo sapiens]                                 57   3e-08
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma...    57   3e-08
gi|154091020 leucine-rich repeats and calponin homology (CH) dom...    55   1e-07
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap...    55   1e-07
gi|56699482 hypothetical protein LOC25940 [Homo sapiens]               54   1e-07

>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
           isoform [Homo sapiens]
          Length = 302

 Score =  647 bits (1668), Expect = 0.0
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 1   MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
           MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
Sbjct: 1   MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60

Query: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
           RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
Sbjct: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120

Query: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
           APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
Sbjct: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180

Query: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKLRWNTH 240
           SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKLRWNTH
Sbjct: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKLRWNTH 240

Query: 241 RPAPWHALSRLCLLIRCLLCLECAYPLPLHLVNSYSSKTQLHCLHLWEACPAYSRQNQSF 300
           RPAPWHALSRLCLLIRCLLCLECAYPLPLHLVNSYSSKTQLHCLHLWEACPAYSRQNQSF
Sbjct: 241 RPAPWHALSRLCLLIRCLLCLECAYPLPLHLVNSYSSKTQLHCLHLWEACPAYSRQNQSF 300

Query: 301 PP 302
           PP
Sbjct: 301 PP 302


>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
           sapiens]
          Length = 411

 Score =  495 bits (1274), Expect = e-140
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
           MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
Sbjct: 1   MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60

Query: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
           RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
Sbjct: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120

Query: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
           APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
Sbjct: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180

Query: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK 234
           SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK
Sbjct: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK 234


>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
          Length = 291

 Score =  132 bits (331), Expect = 5e-31
 Identities = 61/87 (70%), Positives = 75/87 (86%)

Query: 148 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFD 207
           KR +CPALP GW++EEV R+SGLSAG  DV+Y+SPSGKKFRSKPQLARYLG ++DLS+FD
Sbjct: 4   KRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFD 63

Query: 208 FRTGKMMPSKLQKNKQRLRNDPLNQNK 234
           FRTGKM+ SK+ K++QR+R D  NQ K
Sbjct: 64  FRTGKMLMSKMNKSRQRVRYDSSNQVK 90


>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
           sapiens]
          Length = 586

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65

Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
            G       K  P  +   K++  + P    K
Sbjct: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97


>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
           sapiens]
          Length = 503

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65

Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
            G       K  P  +   K++  + P    K
Sbjct: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97


>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
           sapiens]
          Length = 556

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65

Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
            G       K  P  +   K++  + P    K
Sbjct: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97


>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
           sapiens]
          Length = 605

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65

Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
            G       K  P  +   K++  + P    K
Sbjct: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97


>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
           sapiens]
          Length = 549

 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)

Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
           +DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG   DL+ FDF+
Sbjct: 6   LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65

Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
            G       K  P  +   K++  + P    K
Sbjct: 66  QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 52/119 (43%), Positives = 56/119 (47%), Gaps = 20/119 (16%)

Query: 13  EQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGG-GRGRGRWKQAGRGG 71
           +++EG    GG G GG      GG G              G RGG G G G W   G GG
Sbjct: 327 KRQEGGGGRGGWGGGGGGGGRGGGGGG-------------GGRGGWGGGGGGWGGGGGGG 373

Query: 72  GVCGRGRGRGRGRGRGRGRGRGRG----RPPSGGSGLGGD--GGGCGGGGSGGGGAPRR 124
           G  G G G GRG  +GRG   GRG    R   GG G G    GGG GGGG GGGG  RR
Sbjct: 374 GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432



 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 44/119 (36%), Positives = 52/119 (43%), Gaps = 11/119 (9%)

Query: 33  EQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGR 92
           ++GG+ + + P P      +  + GG GRG W   G GGG  G G G GRG   G G G 
Sbjct: 307 DRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGW 366

Query: 93  GRGRPPSGGSGLGGDG-----------GGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
           G G    GG G GG G           GG GG G  GG   R    P+  G  G G  G
Sbjct: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGG 425


>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
          Length = 498

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 47/118 (39%), Positives = 61/118 (51%), Gaps = 10/118 (8%)

Query: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
           G G AP       P  SA P  R     + G   D P LP GW ++   RKSG SAGK D
Sbjct: 79  GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 133

Query: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP 229
           VY  +P GK FRSK +L  Y   +G+T +D + FDF  TG+  PS+ ++   +    P
Sbjct: 134 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP 191


>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
          Length = 486

 Score = 72.8 bits (177), Expect = 4e-13
 Identities = 47/118 (39%), Positives = 61/118 (51%), Gaps = 10/118 (8%)

Query: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
           G G AP       P  SA P  R     + G   D P LP GW ++   RKSG SAGK D
Sbjct: 67  GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 121

Query: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP 229
           VY  +P GK FRSK +L  Y   +G+T +D + FDF  TG+  PS+ ++   +    P
Sbjct: 122 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSP 179


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 49/117 (41%), Positives = 51/117 (43%), Gaps = 15/117 (12%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GG        G S  GGSG+GG S    GG G        SG    G  GGG   G    
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSG---GGYGGG------SGGGHSGGSGGGHSGG---S 554

Query: 67  AGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGG---SGGGG 120
            G  GG  G G G G G G G G   G G    GGSG GG+ GG  GGG   SG GG
Sbjct: 555 GGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611



 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 54/145 (37%), Positives = 58/145 (40%), Gaps = 6/145 (4%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           G G+       G   + G G+ G S    GG GS       SG R  G  GG  G G   
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR--GGSGGSYGGGSGS 526

Query: 66  QAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGS---GGGGAP 122
             G GGG  G G G G   G G G   G G    GGSG GG  GG  GGGS   GG G  
Sbjct: 527 GGGSGGGY-GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585

Query: 123 RREPVPFPSGSAGPGPRGPRATESG 147
                 F   S G    G  A+ SG
Sbjct: 586 HGGGSGFGGESGGSYGGGEEASGSG 610



 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 48/123 (39%), Positives = 52/123 (42%), Gaps = 3/123 (2%)

Query: 17  GESAAGGSGAG-GDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG-GGVC 74
           G    GGSG G G  +  +GG G +      SG    G  GGG G G    +G G  G  
Sbjct: 495 GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGS 554

Query: 75  GRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSA 134
           G   G G G G G G G G G    GGSG G  GGG G GG  GG     E      G  
Sbjct: 555 GGNYGGGSGSGGGSGGGYGGGSGSRGGSG-GSHGGGSGFGGESGGSYGGGEEASGSGGGY 613

Query: 135 GPG 137
           G G
Sbjct: 614 GGG 616



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 53/140 (37%), Positives = 58/140 (41%), Gaps = 23/140 (16%)

Query: 14  QEEGESAAGGS-GAGGDSAIEQGGQGSALAPSPVSGVRRE---GARGGGRGRGRWKQAGR 69
           QE+ ES+  G  G GG     +GG G +       G       G  GGG G G   + G 
Sbjct: 462 QEDFESSGAGKIGLGG-----RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS 516

Query: 70  GGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCG--GGGSGGGGAPRREPV 127
           GG     G G G G G G G G G G   SGGSG G  GG  G  GGGSG GG       
Sbjct: 517 GGSY---GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG------ 567

Query: 128 PFPSGSAGPGPRGPRATESG 147
              SG    G  G R    G
Sbjct: 568 ---SGGGYGGGSGSRGGSGG 584



 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 49/144 (34%), Positives = 51/144 (35%), Gaps = 2/144 (1%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GGR       G  + GGSG         GG G        SG    G  G G G G    
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG 535

Query: 67  AGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRPPSGGSGLG-GDGGGCGGGGSGGGGAPRR 124
            G GGG  G  G G   G G   G G G G    GG G G G  GG GG   GG G    
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE 595

Query: 125 EPVPFPSGSAGPGPRGPRATESGK 148
               +  G    G  G     SGK
Sbjct: 596 SGGSYGGGEEASGSGGGYGGGSGK 619



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 43/104 (41%), Positives = 47/104 (45%), Gaps = 11/104 (10%)

Query: 19  SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
           S++GG G GG  +   G  G         G  R   RGGG   G     G GGG      
Sbjct: 36  SSSGGGGGGGRFSSSSGYGG---------GSSRVCGRGGGGSFGYSYGGGSGGGFSASSL 86

Query: 79  GRGRGRG-RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
           G G G G RG G   G G   SGG G GG GGG GGG  GG G+
Sbjct: 87  GGGFGGGSRGFGGASGGGYSSSGGFG-GGFGGGSGGGFGGGYGS 129



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 44/118 (37%), Positives = 49/118 (41%), Gaps = 16/118 (13%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQ---GGQGSALAPSPVSGVRREGARGGGRGRG 62
           GGGR       G  ++   G GG  +      GG G   + S + G    G  GG RG G
Sbjct: 43  GGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG----GFGGGSRGFG 98

Query: 63  RWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
                G  GG      G G G G G G G G G     GSG GG GG  GG G G GG
Sbjct: 99  -----GASGGGYSSSGGFGGGFGGGSGGGFGGGY----GSGFGGFGGFGGGAGGGDGG 147



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 42/102 (41%), Positives = 47/102 (46%), Gaps = 16/102 (15%)

Query: 24  SGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA-GRGGG---VCGRGRG 79
           SG GG   +  GG       S  S   R  + GGG G GR+  + G GGG   VCGRG G
Sbjct: 14  SGGGGGGGLGSGG-------SIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66

Query: 80  RGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGG-GGSGGGG 120
              G   G G G G      GG    G GGG  G GG+ GGG
Sbjct: 67  GSFGYSYGGGSGGGFSASSLGG----GFGGGSRGFGGASGGG 104



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 39/114 (34%), Positives = 42/114 (36%), Gaps = 21/114 (18%)

Query: 27  GGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR 86
           GG    E  G G         G+   G  GG  GRG   + G GG   G G G G G G 
Sbjct: 460 GGQEDFESSGAGKI-------GLGGRGGSGGSYGRG--SRGGSGGSYGGGGSGGGYGGGS 510

Query: 87  GRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
           G      RG       G GG  GG  G G G GG          SG +G G  G
Sbjct: 511 G-----SRG-------GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 31/85 (36%), Positives = 35/85 (41%), Gaps = 9/85 (10%)

Query: 4   HPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGR 63
           H GG         G +  GGSG+GG S    GG G        SG    G+ GGG G G 
Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGSGGGSG---GGYGGGSGSRGGSG----GSHGGGSGFGG 594

Query: 64  WKQAGRGGG--VCGRGRGRGRGRGR 86
                 GGG    G G G G G G+
Sbjct: 595 ESGGSYGGGEEASGSGGGYGGGSGK 619



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 102 SGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
           S L   GGG GGGG G GG+ R     F S S G G  G  ++ SG
Sbjct: 9   SYLSRSGGG-GGGGLGSGGSIRSSYSRF-SSSGGGGGGGRFSSSSG 52


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 47/109 (43%), Positives = 56/109 (51%), Gaps = 9/109 (8%)

Query: 18  ESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG-----GG 72
           ++A GGSG  G S+   GG  S+ + S  SG R+ G+RGG  G G     G G     GG
Sbjct: 515 KAAFGGSGGRGSSS---GGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGG 571

Query: 73  VCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
             G G G   G   G G G G G+  SGG   GG   G GG GSGGGG+
Sbjct: 572 RYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG-GGYGSGGGGS 619



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 55/150 (36%), Positives = 60/150 (40%), Gaps = 20/150 (13%)

Query: 11  CPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ---A 67
           C  +  G    G  G    SA+  GG  S  + S  S + R G  GGG G G +      
Sbjct: 7   CKSRGRGGGGGGFRGFSSGSAVVSGG--SRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLV 64

Query: 68  GRGG------GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGG-GSGGGG 120
           G GG       V G G G G   G G GRG G G    GGS  GG  G  GGG G GG G
Sbjct: 65  GLGGTKSISISVAGGGGGFGAAGGFG-GRGGGFG----GGSSFGGGSGFSGGGFGGGGFG 119

Query: 121 APRREPVPFP---SGSAGPGPRGPRATESG 147
             R      P    G  GPG  GP     G
Sbjct: 120 GGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 45/111 (40%), Positives = 49/111 (44%), Gaps = 5/111 (4%)

Query: 10  CCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGG--GRGRGRWKQA 67
           C      G    GG G G  S +  GG  S ++ S   G    GA GG  GRG G    +
Sbjct: 42  CLSRHGGGGGGFGGGGFGSRSLVGLGGTKS-ISISVAGGGGGFGAAGGFGGRGGGFGGGS 100

Query: 68  GRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGG 118
             GGG    G G G G G G GR  G G P  G  GLGG GG   GG  GG
Sbjct: 101 SFGGGSGFSGGGFGGG-GFGGGRFGGFGGP-GGVGGLGGPGGFGPGGYPGG 149



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 19/111 (17%)

Query: 47  SGVRREGARGGGRGRGRWKQAGRGGGVC----------GRGRGRGRGRGRGRGRGRGRGR 96
           S V  + A GG  GRG     G   G             RG   G G   G G G G G 
Sbjct: 510 SNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGS 569

Query: 97  PPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
               GSG G  GG   GGG G GG            S+G G RG  ++  G
Sbjct: 570 GGRYGSGGGSKGGSISGGGYGSGGGKH---------SSGGGSRGGSSSGGG 611



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 33/101 (32%), Positives = 39/101 (38%), Gaps = 16/101 (15%)

Query: 17  GESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
           G  +    G+GG  +I  GG GS             G R G  G        +GG + G 
Sbjct: 543 GRQSGSRGGSGGGGSISGGGYGSGGG---------SGGRYGSGG------GSKGGSISGG 587

Query: 77  GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
           G G G G+    G  RG G    GG G GG G     G SG
Sbjct: 588 GYGSGGGKHSSGGGSRG-GSSSGGGYGSGGGGSSSVKGSSG 627


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 50/133 (37%), Positives = 56/133 (42%), Gaps = 9/133 (6%)

Query: 16  EGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCG 75
           EGE ++GG G GG S    GG G   +    SG    G  GG  G G +     GGG  G
Sbjct: 454 EGEGSSGGGGRGGGSF--GGGYGGGSSGGGSSGGGHGGGHGGSSGGG-YGGGSSGGGSSG 510

Query: 76  RGRGRGR---GRGRGRGRGRGRGRPPSGGSGLG--GDGGGCGGGGSGGGGAPRREPVPFP 130
            G G G    G G     G G G    GG G G    GGG   GG  GGG+         
Sbjct: 511 GGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSS 570

Query: 131 SGSAG-PGPRGPR 142
           SGS G    +GPR
Sbjct: 571 SGSVGESSSKGPR 583



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 46/122 (37%), Positives = 51/122 (41%), Gaps = 12/122 (9%)

Query: 19  SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
           S +GG G GG      GG  S+L  S   G    G   GG   G + +   GGG  G   
Sbjct: 14  SRSGGGGGGGGCG--GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSS 71

Query: 79  GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGP 138
           G   G G   G G G  R   G S  GG  GG  GGGS GGG+       F  GS G G 
Sbjct: 72  GGYGGLG---GFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS-------FGGGSFGGGG 121

Query: 139 RG 140
            G
Sbjct: 122 FG 123



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 37/104 (35%), Positives = 42/104 (40%), Gaps = 7/104 (6%)

Query: 19  SAAGGSGAGGDS--AIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
           S  GG  +GG S  +  +G  G         G    G  GGG  RG +  +  GG     
Sbjct: 42  SLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSY--- 98

Query: 77  GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             G   G G   G   G G    GG G GG GGG GGG  G GG
Sbjct: 99  --GGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 53/143 (37%), Positives = 58/143 (40%), Gaps = 17/143 (11%)

Query: 11  CPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG 70
           C +   G    GGSG GG      GG G   + S        G  GGG G G     G G
Sbjct: 16  CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGS-SGGGGG 74

Query: 71  GGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGL---GGDGGGC---GGGGSGGGGAPRR 124
           GG+ G G G G     G  +  G G    GGSG    GG G GC   GGGGS GGG+   
Sbjct: 75  GGIGGCGGGSG-----GSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG-- 127

Query: 125 EPVPFPSGSAGPGPRGPRATESG 147
               F SG  G    G     SG
Sbjct: 128 ---CFSSGGGGSSGGGSGCFSSG 147



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 63/197 (31%), Positives = 69/197 (35%), Gaps = 57/197 (28%)

Query: 6   GGGRCCPEQEEGESAAGGSG----------AGGDSAIEQGG---QGSALAPSPVSGVRRE 52
           GGG  C     G S+ GGSG           GG      GG    G A+      GV   
Sbjct: 108 GGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG 167

Query: 53  GARGGGRGRGRWKQAGRGGGVCG-RGRGRGRGRGRGRGRGRG-----------------R 94
           G+ GG  G G +   G GG VCG  G G G G G   G G G                  
Sbjct: 168 GSSGG--GSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSY 225

Query: 95  GRPPSGGSGLGGDG----------GGCGGGGSG--------GGGAPRREPVPFPSGSAGP 136
           G   SGG G GG G           GCGGG SG        GGG+          GS+G 
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS------VCGGGSSGG 279

Query: 137 GPRGPRATESGKRMDCP 153
           G  G     SG     P
Sbjct: 280 GGGGSSVGGSGSGKGVP 296



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 42/101 (41%), Positives = 44/101 (43%), Gaps = 9/101 (8%)

Query: 45  PVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGL 104
           PV  V+  G  GGG G G       GGG  G G   G G G   G G   G    G SG 
Sbjct: 13  PVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSS-GSGCGYSGGGGYSGGGCGGGSSGG 71

Query: 105 GGDG--GGCGGGG------SGGGGAPRREPVPFPSGSAGPG 137
           GG G  GGCGGG       SGGGG+       F SG  G G
Sbjct: 72  GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSG 112



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 50/147 (34%), Positives = 57/147 (38%), Gaps = 26/147 (17%)

Query: 19  SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGAR------GGGRGRGRWKQAGRGGG 72
           S  GGS  GG      GG GS    S   G    G+       GG  G G    +  GGG
Sbjct: 91  SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150

Query: 73  VCGRG---RGRGRGRGRGRGRGRGRGRPPSGGSG-----LGGDGGGCGGGGSGGGGA--- 121
             G+    +  G G   G   G G G   SGG G       G G GCGGG SGG G+   
Sbjct: 151 FSGQAVQCQSYG-GVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYV 209

Query: 122 -----PRREPVPFPS---GSAGPGPRG 140
                 +    P PS   GS+G G  G
Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGGGSG 236



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 42/117 (35%), Positives = 46/117 (39%), Gaps = 26/117 (22%)

Query: 8   GRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
           G  C     G  + GG G G       GG G  +           G  GGG G G  K +
Sbjct: 48  GSGCGYSGGGGYSGGGCGGGSSG----GGGGGGI-----------GGCGGGSG-GSVKYS 91

Query: 68  GRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGC---GGGGSGGGGA 121
           G GG         G G G     G G G   SGG G  G G GC   GGGGS GGG+
Sbjct: 92  GGGG-------SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGS 141



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 7/52 (13%)

Query: 96  RPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
           +PP       G GGG GG G GG G        F  G +G G  G     SG
Sbjct: 11  QPPVDCVKTSGGGGGGGGSGGGGCGF-------FGGGGSGGGSSGSGCGYSG 55


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 51/121 (42%), Positives = 54/121 (44%), Gaps = 13/121 (10%)

Query: 2   RAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGR 61
           R+  GGGR       G S   G G G  S +  GG  S         +    ARGGGRG 
Sbjct: 38  RSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKS---------ISISVARGGGRGS 88

Query: 62  GRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
           G     G GGG  G G   G G G G   G G G   SGG G G  GGG GGGG GGG  
Sbjct: 89  GFG--GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFG--GGGFGGGGYGGGYG 144

Query: 122 P 122
           P
Sbjct: 145 P 145



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 45/124 (36%), Positives = 49/124 (39%), Gaps = 16/124 (12%)

Query: 8   GRCCPEQEEGESAA------GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGR 61
           G C P      S +      GGS  GG      GG GS  +     G       GGG GR
Sbjct: 495 GECAPNVSVSVSTSHTTISGGGSRGGGG-----GGYGSGGSSYGSGGGSYGSGGGGGGGR 549

Query: 62  GRWKQAGR----GGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
           G +   G     GGG  G G G G     G G   G  R  SGG G GG  GG G GG  
Sbjct: 550 GSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG-GGSSGGRGSGGGS 608

Query: 118 GGGA 121
            GG+
Sbjct: 609 SGGS 612



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 39/100 (39%), Positives = 41/100 (41%), Gaps = 1/100 (1%)

Query: 22  GGSGAGGDSAIEQGGQ-GSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGR 80
           GG G+GG S    GG  GS        G    G    G G G +   G GGG    G G 
Sbjct: 523 GGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGS 582

Query: 81  GRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             G  RG   G G G     GSG G  GG  GG GS  GG
Sbjct: 583 SSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 11/105 (10%)

Query: 17  GESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
           G   +GG G GG  +   GG          SG    G+ GGG G G +      GG  G 
Sbjct: 537 GSYGSGGGGGGGRGSYGSGGSSYG------SGGGSYGSGGGGGGHGSYGSGSSSGGYRGG 590

Query: 77  GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
             G G G   GRG G G     S G  +GG G   GG  S GG +
Sbjct: 591 SGGGGGGSSGGRGSGGG-----SSGGSIGGRGSSSGGVKSSGGSS 630



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 59/176 (33%), Positives = 67/176 (38%), Gaps = 47/176 (26%)

Query: 19  SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRG- 77
           S+  G  +GG  +    G  +    +  S  RR G  GGG   GR+   G GGG  G G 
Sbjct: 6   SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSG--GGG---GRFSSCGGGGGSFGAGG 60

Query: 78  ---------------------RGRGRGRGRGRGRGRGR-GRPPSGGSGLGG---DGGGCG 112
                                RG GRG G G G G G  G    GG G GG    GGG G
Sbjct: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120

Query: 113 GGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKS 168
           G GSGGGG        F  G  G G  G            P  PPG  +E  I +S
Sbjct: 121 GFGSGGGG--------FGGGGFGGGGYGGGYG--------PVCPPGGIQEVTINQS 160



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 44/115 (38%), Positives = 48/115 (41%), Gaps = 18/115 (15%)

Query: 46  VSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR----GRGRGRGRGRPPSGG 101
           +SG    G  GGG G G     G GGG  G G G G GRG     G   G G G   SGG
Sbjct: 512 ISGGGSRGGGGGGYGSGG-SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG 570

Query: 102 SGLG----GDGGGCGG-----GGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
            G G    G G   GG     GG GGG +  R       G +  G  G R + SG
Sbjct: 571 GGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG----SGGGSSGGSIGGRGSSSG 621


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 55/161 (34%), Positives = 68/161 (42%), Gaps = 21/161 (13%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GG   P    G     GSG GG  +  QG    +   +  SG   +G+RGG    G+   
Sbjct: 484 GGDYMPMNNWGSGNGRGSG-GGQGSNGQGSSSHSSGGNQCSG-EGQGSRGGQGSNGQ--- 538

Query: 67  AGRGGGVCGR-GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
            G GG  C R G+G   G G G G+  G G    GG G  GDG G GGG + GGG     
Sbjct: 539 -GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQG-PGDGHGSGGGKNSGGGKGSGS 596

Query: 126 PVPFPSGSAGPGPRGP---------RATESGKRMDCPALPP 157
                 GS G G RG          + T+S ++   P  PP
Sbjct: 597 ----GKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPP 633



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 48/148 (32%), Positives = 63/148 (42%), Gaps = 8/148 (5%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREG-ARGGGRGRGRW 64
           GGG+    Q     ++GG+   G+    +GGQGS    S  +   R+G    GG G G  
Sbjct: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGG 561

Query: 65  KQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGG----SGGGG 120
           ++ G G G  G G+G G G G G G+  G G+    GSG G DG G  G      S  G 
Sbjct: 562 QRPGGGHG-SGGGQGPGDGHGSGGGKNSGGGK--GSGSGKGSDGDGERGKSLKKRSYFGK 618

Query: 121 APRREPVPFPSGSAGPGPRGPRATESGK 148
             + +    P     P P  P     GK
Sbjct: 619 LTQSKQQQMPPPPPPPPPPPPAGGTGGK 646


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 54/149 (36%), Positives = 62/149 (41%), Gaps = 16/149 (10%)

Query: 3   AHPGGGRCCPEQEEGESAAG---GSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR 59
           AH GG         G  A G   G+G  G  ++   G   +++ S  +G    G+R GG 
Sbjct: 33  AHSGGA--------GGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAG----GSRAGGF 80

Query: 60  GRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGG- 118
           G GR   A  GG   G G G G G G G G GRG G    G  G GG GG  G GG GG 
Sbjct: 81  GGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGP 140

Query: 119 GGAPRREPVPFPSGSAGPGPRGPRATESG 147
           GG         P     PG  GP     G
Sbjct: 141 GGFGGSGGFGGPGSLGSPGGFGPGGFPGG 169



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 35/82 (42%), Positives = 40/82 (48%), Gaps = 12/82 (14%)

Query: 39  SALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPP 98
           SA++ S VS      + GG  G       G GGG+ G G G G   G G G G GRG   
Sbjct: 519 SAVSISVVSSSTTSASAGGYGG-------GYGGGM-GGGLGGGFSAGGGSGSGFGRG--- 567

Query: 99  SGGSGLGGDGGGCGGGGSGGGG 120
            GG G+GG  GG   G SGG G
Sbjct: 568 -GGGGIGGGFGGGSSGFSGGSG 588



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/69 (46%), Positives = 32/69 (46%), Gaps = 7/69 (10%)

Query: 53  GARGGGRGRGRWKQAGRG---GGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGG 109
           G  GGG G G     G G   GG  G G GRG G G G G G G     SGGSG G   G
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFG-GGSSGFSGGSGFGSISG 594

Query: 110 ---GCGGGG 115
              G  GGG
Sbjct: 595 ARYGVSGGG 603



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 8/71 (11%)

Query: 79  GRGRGRGRGRGRGRGRGRPPSGGSGLG-GDGGGCG-GGGSGGGGAPRREPVPFPSGSAGP 136
           G G G G G G G G G    GGSG G G GGG G GGG GGG +       F  GS   
Sbjct: 537 GYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSS------GFSGGSGFG 590

Query: 137 GPRGPRATESG 147
              G R   SG
Sbjct: 591 SISGARYGVSG 601



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 30/91 (32%), Positives = 32/91 (35%), Gaps = 6/91 (6%)

Query: 19  SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
           S+   + AGG      GG G  L      G    G  G G GRG     G GGG  G   
Sbjct: 528 SSTTSASAGGYGGGYGGGMGGGLG----GGFSAGGGSGSGFGRGGG--GGIGGGFGGGSS 581

Query: 79  GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGG 109
           G   G G G   G   G    G S     GG
Sbjct: 582 GFSGGSGFGSISGARYGVSGGGFSSASNRGG 612



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 8/85 (9%)

Query: 35  GGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGR 94
           GG G         G+    + GGG G G     GRGG   G G G G G G   G   G 
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSG----FGRGG---GGGIGGGFG-GGSSGFSGGS 587

Query: 95  GRPPSGGSGLGGDGGGCGGGGSGGG 119
           G     G+  G  GGG     + GG
Sbjct: 588 GFGSISGARYGVSGGGFSSASNRGG 612



 Score = 28.1 bits (61), Expect = 10.0
 Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 1/37 (2%)

Query: 99  SGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAG 135
           +GG G GG GGG GGG  GG  A       F  G  G
Sbjct: 535 AGGYG-GGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG 570


>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 44/98 (44%), Positives = 48/98 (48%), Gaps = 21/98 (21%)

Query: 55  RGGG-RGRGRWKQAGRGGGVCGRGRGRGRGRG-RGRGRGRGRGRPPSGGSGLGGDGGGCG 112
           RGGG  GRG +   G  GG  G G GRGRG G RGRGRG             GG GGG G
Sbjct: 8   RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRG-------------GGGGGGGG 54

Query: 113 GGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRM 150
           GGG  GGG           G+ G G  G R  +SGK +
Sbjct: 55  GGGGRGGGGFH------SGGNRGRGRGGKRGNQSGKNV 86



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRG 81
          GG G  GD    +GG+G         G  R   RGGG G G     GRGGG    G  RG
Sbjct: 13 GGRGGFGDRG-GRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71

Query: 82 RGRGRGRGRGRGR 94
          RGRG  RG   G+
Sbjct: 72 RGRGGKRGNQSGK 84



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 10/64 (15%)

Query: 6  GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
          GGGR       G    GG G GG      GG+G         G    G RG GRG  R  
Sbjct: 31 GGGRGRGGGFRGRGRGGGGGGGGGGG---GGRGG-------GGFHSGGNRGRGRGGKRGN 80

Query: 66 QAGR 69
          Q+G+
Sbjct: 81 QSGK 84


>gi|28875797 small protein rich in arginine and glycine [Homo
           sapiens]
          Length = 248

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 44/103 (42%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQG--------SALAPSPVSGVRREGARG-G 57
           GGR  P  + G    G  G      + +GG             A +P  G+RR G RG G
Sbjct: 101 GGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRG 160

Query: 58  GRGRGRWKQAGRG-GGVCGRGRG---RGRGRGRGRGRGRGRGR 96
           G GRG   +   G GG+ GRGRG   RGRG   GRGRGRGRGR
Sbjct: 161 GPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGR 203



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 41/106 (38%), Positives = 46/106 (43%), Gaps = 14/106 (13%)

Query: 31  AIEQGGQGSALAPSPVSGVRREGARGGGRGRG--------RWKQAGRGGGVC----GRGR 78
           A+ +G  G    P    G+ R G RGG   R         R +   RGG       G  R
Sbjct: 94  ALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRR 153

Query: 79  GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRR 124
           G  RGRG G GRG G GR   G  G+GG G G  G G GG G   R
Sbjct: 154 GGVRGRG-GPGRG-GLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGR 197


>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
          Length = 589

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 44/119 (36%), Positives = 49/119 (41%), Gaps = 9/119 (7%)

Query: 12  PEQEEGESAAG---GSGAGGDSAIE-QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
           P  E+   + G   G G GG+     +GG+G         G R  G  GG R  G     
Sbjct: 379 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG--YGGDRSGGGYGGDRSSGGGYSG 436

Query: 68  GRGGGVCG---RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPR 123
            R GG  G    G G G  RG G G  RG G     G G GGD GG GG   GG G  R
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR 495



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 56/149 (37%), Positives = 58/149 (38%), Gaps = 12/149 (8%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQ--GSALAPSPVSGVRREGARGGGRGRGR 63
           GGG        G     G G GGD     GG   G         G  R G  GG RG   
Sbjct: 440 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 499

Query: 64  WKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGD-GGGCGGGGSGGGGAP 122
             + G GG   G G  RG G G  R RG G G    GGSG GGD  GG GG  SGGG   
Sbjct: 500 GDRGGYGGDRGGYGGDRG-GYGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557

Query: 123 RREPVPFPSGSAGPGPRGPRATESGKRMD 151
            R       G    G RG    + G R D
Sbjct: 558 DR-------GGGYGGDRGGYGGKMGGRND 579



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 48/120 (40%), Positives = 51/120 (42%), Gaps = 10/120 (8%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GGR       G   +GG G GGD +   GG     +     G R  G  GG RG G    
Sbjct: 406 GGRGGDRGGYGGDRSGG-GYGGDRS-SGGGYSGDRSGGGYGGDRSGGGYGGDRGGG--YG 461

Query: 67  AGRGGGVCG-RGRGRGRGRG-----RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             RGGG  G RG G G  RG     RG G G  RG       G GGD GG GG   G GG
Sbjct: 462 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 521



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 42/108 (38%), Positives = 43/108 (39%), Gaps = 9/108 (8%)

Query: 45  PVSGVRREGARGGGRG-RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSG 103
           P  G  R    GG RG RGR  + G  GG  G   G G G  R  G G    R    G G
Sbjct: 386 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR---SGGG 442

Query: 104 LGGD--GGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
            GGD  GGG GG   GG G  R        G  G G  G R    G R
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGY---GGDRGGGYGGDRGGYGGDR 487



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 42/112 (37%), Positives = 42/112 (37%), Gaps = 20/112 (17%)

Query: 48  GVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRG-----RGRGRGRGRPPSG-- 100
           G R  G RGG RG       G GG   G G G  R  G G      G G G  R   G  
Sbjct: 401 GYRGRGGRGGDRG-------GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 453

Query: 101 ---GSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
              G G GGD GG  GG  GGG    R       G  G G  G R    G R
Sbjct: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGY---GGDRGGGYGGDRGGYGGDR 502



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/150 (36%), Positives = 58/150 (38%), Gaps = 35/150 (23%)

Query: 6   GGGRCCPEQEEGESAAGG-SGAGGDSAIEQGGQGSALAPSPVSG----VRREGARGGGRG 60
           GGGR       G    GG  G GGD        G  + P+P  G     RR         
Sbjct: 328 GGGR---RGRGGYRGRGGFQGRGGDPK-----SGDWVCPNPSCGNMNFARRNSCNQCNEP 379

Query: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRG-RGRGRGRGRPPSG------GSGLGGD---GGG 110
           R    +  R  G  G  RGRG G  RG RGRG GRG    G      G G GGD   GGG
Sbjct: 380 R---PEDSRPSG--GDFRGRGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGG 433

Query: 111 CGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
             G  SGGG    R      SG    G RG
Sbjct: 434 YSGDRSGGGYGGDR------SGGGYGGDRG 457



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 38/126 (30%), Positives = 41/126 (32%), Gaps = 51/126 (40%)

Query: 69  RGGGVCGRGRGRGRGRGRG----------------------------------------- 87
           RGGG  G  RGRG  RGRG                                         
Sbjct: 323 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382

Query: 88  ---------RGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGG-GAPRREPVPFPSGSAGPG 137
                    RGRG G  R   G  G GGD GG GG  SGGG G  R     +    +G G
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442

Query: 138 PRGPRA 143
             G R+
Sbjct: 443 YGGDRS 448



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 72  GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
           G   RG G  +G GRGRG     GR P  GS  GGD GG    G      PR +
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYGPRTD 220



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GG R     + G       G GGD +  +GG G         G  R G  GG R  G + 
Sbjct: 499 GGDRGGYGGDRGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY- 555

Query: 66  QAGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRP 97
              RGGG  G RG   G+  GR   R   R RP
Sbjct: 556 GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRP 588



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 17/41 (41%), Positives = 22/41 (53%)

Query: 53  GARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRG 93
           G++GGGRGRG + + GRG      G  RG  +  G  R  G
Sbjct: 176 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216


>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
          Length = 592

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 44/119 (36%), Positives = 49/119 (41%), Gaps = 9/119 (7%)

Query: 12  PEQEEGESAAG---GSGAGGDSAIE-QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
           P  E+   + G   G G GG+     +GG+G         G R  G  GG R  G     
Sbjct: 382 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG--YGGDRSGGGYGGDRSSGGGYSG 439

Query: 68  GRGGGVCG---RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPR 123
            R GG  G    G G G  RG G G  RG G     G G GGD GG GG   GG G  R
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR 498



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 56/149 (37%), Positives = 58/149 (38%), Gaps = 12/149 (8%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQ--GSALAPSPVSGVRREGARGGGRGRGR 63
           GGG        G     G G GGD     GG   G         G  R G  GG RG   
Sbjct: 443 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 502

Query: 64  WKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGD-GGGCGGGGSGGGGAP 122
             + G GG   G G  RG G G  R RG G G    GGSG GGD  GG GG  SGGG   
Sbjct: 503 GDRGGYGGDRGGYGGDRG-GYGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560

Query: 123 RREPVPFPSGSAGPGPRGPRATESGKRMD 151
            R       G    G RG    + G R D
Sbjct: 561 DR-------GGGYGGDRGGYGGKMGGRND 582



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 48/120 (40%), Positives = 51/120 (42%), Gaps = 10/120 (8%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GGR       G   +GG G GGD +   GG     +     G R  G  GG RG G    
Sbjct: 409 GGRGGDRGGYGGDRSGG-GYGGDRS-SGGGYSGDRSGGGYGGDRSGGGYGGDRGGG--YG 464

Query: 67  AGRGGGVCG-RGRGRGRGRG-----RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             RGGG  G RG G G  RG     RG G G  RG       G GGD GG GG   G GG
Sbjct: 465 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 524



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 42/108 (38%), Positives = 43/108 (39%), Gaps = 9/108 (8%)

Query: 45  PVSGVRREGARGGGRG-RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSG 103
           P  G  R    GG RG RGR  + G  GG  G   G G G  R  G G    R    G G
Sbjct: 389 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR---SGGG 445

Query: 104 LGGD--GGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
            GGD  GGG GG   GG G  R        G  G G  G R    G R
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGY---GGDRGGGYGGDRGGYGGDR 490



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 42/112 (37%), Positives = 42/112 (37%), Gaps = 20/112 (17%)

Query: 48  GVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRG-----RGRGRGRGRPPSG-- 100
           G R  G RGG RG       G GG   G G G  R  G G      G G G  R   G  
Sbjct: 404 GYRGRGGRGGDRG-------GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 456

Query: 101 ---GSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
              G G GGD GG  GG  GGG    R       G  G G  G R    G R
Sbjct: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGY---GGDRGGGYGGDRGGYGGDR 505



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/150 (36%), Positives = 58/150 (38%), Gaps = 35/150 (23%)

Query: 6   GGGRCCPEQEEGESAAGG-SGAGGDSAIEQGGQGSALAPSPVSG----VRREGARGGGRG 60
           GGGR       G    GG  G GGD        G  + P+P  G     RR         
Sbjct: 331 GGGR---RGRGGYRGRGGFQGRGGDPK-----SGDWVCPNPSCGNMNFARRNSCNQCNEP 382

Query: 61  RGRWKQAGRGGGVCGRGRGRGRGRGRG-RGRGRGRGRPPSG------GSGLGGD---GGG 110
           R    +  R  G  G  RGRG G  RG RGRG GRG    G      G G GGD   GGG
Sbjct: 383 R---PEDSRPSG--GDFRGRGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGG 436

Query: 111 CGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
             G  SGGG    R      SG    G RG
Sbjct: 437 YSGDRSGGGYGGDR------SGGGYGGDRG 460



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 38/126 (30%), Positives = 41/126 (32%), Gaps = 51/126 (40%)

Query: 69  RGGGVCGRGRGRGRGRGRG----------------------------------------- 87
           RGGG  G  RGRG  RGRG                                         
Sbjct: 326 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385

Query: 88  ---------RGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGG-GAPRREPVPFPSGSAGPG 137
                    RGRG G  R   G  G GGD GG GG  SGGG G  R     +    +G G
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445

Query: 138 PRGPRA 143
             G R+
Sbjct: 446 YGGDRS 451



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 72  GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
           G   RG G  +G GRGRG     GR P  GS  GGD GG    G      PR +
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYGPRTD 223



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 4/93 (4%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GG R     + G       G GGD +  +GG G         G  R G  GG R  G + 
Sbjct: 502 GGDRGGYGGDRGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY- 558

Query: 66  QAGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRP 97
              RGGG  G RG   G+  GR   R   R RP
Sbjct: 559 GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRP 591



 Score = 32.3 bits (72), Expect = 0.53
 Identities = 17/41 (41%), Positives = 22/41 (53%)

Query: 53  GARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRG 93
           G++GGGRGRG + + GRG      G  RG  +  G  R  G
Sbjct: 179 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 48/141 (34%), Positives = 51/141 (36%), Gaps = 17/141 (12%)

Query: 7   GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
           GGR       G    GG   GG       G G  +  S  SG R     GGG G G    
Sbjct: 727 GGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNS--SGHRPHEGPGGGMGSGHRPH 784

Query: 67  AGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREP 126
            G GG + G G G     G G G   G G  P  G G        GG G+GGG  P   P
Sbjct: 785 EGPGGSM-GGGGGHRPHEGPGGGISGGSGHRPHEGPG--------GGMGAGGGHRPHEGP 835

Query: 127 VPFPSGSA------GPGPRGP 141
                GS       GPG  GP
Sbjct: 836 GGSMGGSGGHRPHEGPGHGGP 856



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 48/129 (37%), Positives = 51/129 (39%), Gaps = 9/129 (6%)

Query: 17  GESAAGGSGAG-GDSAIEQGGQGSALAPSPVSGVR--REGARGGGRGRGRWKQAGRGGGV 73
           G    GG G G G     +GG+G    P P    R  R G  GGG   GR    G GGG+
Sbjct: 689 GGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGR---GGPGGGM 745

Query: 74  CGRGRGR---GRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFP 130
            G G  R   G G G G   G      P GG G G       GG  GGGG  R    P  
Sbjct: 746 VGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG 805

Query: 131 SGSAGPGPR 139
             S G G R
Sbjct: 806 GISGGSGHR 814



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/146 (33%), Positives = 52/146 (35%), Gaps = 22/146 (15%)

Query: 2   RAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVR-REGARGG-GR 59
           R H G G             GGS  GG       G G  ++    SG R  EG  GG G 
Sbjct: 768 RPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGG--SGHRPHEGPGGGMGA 825

Query: 60  GRGRWKQAGRGGGVCGRGRGR---GRGRGRGRG---------RGRG-RGRPPSGGSGLGG 106
           G G     G GG + G G  R   G G G   G         RG   RG PP    G  G
Sbjct: 826 GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDG 885

Query: 107 DGGGCGG-----GGSGGGGAPRREPV 127
            G G GG     GG   GG     PV
Sbjct: 886 PGHGGGGHRGHDGGHSHGGDMSNRPV 911



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 39/125 (31%), Positives = 45/125 (36%), Gaps = 19/125 (15%)

Query: 41  LAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR-----------GRG 89
           L P P++     G  GG +G   +   G GG + G   G G   G            G  
Sbjct: 620 LGPGPIANGFPPGGPGGPKGMQHFPP-GPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDP 678

Query: 90  RGRGRGRPPSGGSGLGGDGGGCG----GGGSGGGGAPRREPVPF---PSGSAGPGPRGPR 142
              G G P  GG   GG G G G    G G  GG  P   P PF     G +G GP   R
Sbjct: 679 FWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGR 738

Query: 143 ATESG 147
               G
Sbjct: 739 GGPGG 743



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 3/57 (5%)

Query: 103 GLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAG--PGPRGPRATESGKRMDCPALPP 157
           GL G G    G   GG G P+     FP G  G  PGP G      G R+  P  PP
Sbjct: 618 GLLGPGPIANGFPPGGPGGPKGMQ-HFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPP 673


>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
           B1 [Homo sapiens]
          Length = 353

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 44/109 (40%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 14  QEEGESAAGGSGAGGDSAI-EQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGG 72
           QE  E  +  SG GG+    +  G G    P P S  R  G+ G G GRG       G G
Sbjct: 191 QEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRG-GSDGYGSGRGF------GDG 243

Query: 73  VCGRGRGRGRGR-GRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             G G G G G  G   G G GRG    GG G G  GGG GGG    GG
Sbjct: 244 YNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGG 292



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 49/139 (35%), Positives = 51/139 (36%), Gaps = 21/139 (15%)

Query: 6   GGGRCCP---EQEEGESAAGGSGAG-GDSAIEQGGQ--GSALAPSPVSGVRREGARGGGR 59
           GGG   P       G S   GSG G GD     GG   G     SP  G  R G  GGG 
Sbjct: 215 GGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGP 274

Query: 60  GRGRWKQAGRGGGVCGRGRGR-GRGRGRGRGR-------------GRGRGRPPSGGSGLG 105
           G G  +  G GGG    G G  G G     G              G   G    GG   G
Sbjct: 275 GYGN-QGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 333

Query: 106 GDGGGCGGGGSGGGGAPRR 124
           G+ G  G GGSGG G   R
Sbjct: 334 GNYGPGGSGGSGGYGGRSR 352



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 30/77 (38%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 66  QAGRGGGVCGRGRGRGRGRGRGRGRGRG-RGRPPSGGSGLGGDGGGCGGGGSGGGGAPRR 124
           ++GRGG   G G  RG G   G G G   RG     GSG G  G G  G G G GG    
Sbjct: 200 RSGRGGNF-GFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGF-GDGYNGYGGGPGGGNFG 257

Query: 125 EPVPFPSGSAGPGPRGP 141
               +  G  G G  GP
Sbjct: 258 GSPGYGGGRGGYGGGGP 274


>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
           [Homo sapiens]
          Length = 341

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 44/109 (40%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 14  QEEGESAAGGSGAGGDSAI-EQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGG 72
           QE  E  +  SG GG+    +  G G    P P S  R  G+ G G GRG       G G
Sbjct: 179 QEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRG-GSDGYGSGRGF------GDG 231

Query: 73  VCGRGRGRGRGR-GRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
             G G G G G  G   G G GRG    GG G G  GGG GGG    GG
Sbjct: 232 YNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGG 280



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 49/139 (35%), Positives = 51/139 (36%), Gaps = 21/139 (15%)

Query: 6   GGGRCCP---EQEEGESAAGGSGAG-GDSAIEQGGQ--GSALAPSPVSGVRREGARGGGR 59
           GGG   P       G S   GSG G GD     GG   G     SP  G  R G  GGG 
Sbjct: 203 GGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGP 262

Query: 60  GRGRWKQAGRGGGVCGRGRGR-GRGRGRGRGR-------------GRGRGRPPSGGSGLG 105
           G G  +  G GGG    G G  G G     G              G   G    GG   G
Sbjct: 263 GYGN-QGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGG 321

Query: 106 GDGGGCGGGGSGGGGAPRR 124
           G+ G  G GGSGG G   R
Sbjct: 322 GNYGPGGSGGSGGYGGRSR 340



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 30/77 (38%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 66  QAGRGGGVCGRGRGRGRGRGRGRGRGRG-RGRPPSGGSGLGGDGGGCGGGGSGGGGAPRR 124
           ++GRGG   G G  RG G   G G G   RG     GSG G  G G  G G G GG    
Sbjct: 188 RSGRGGNF-GFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGF-GDGYNGYGGGPGGGNFG 245

Query: 125 EPVPFPSGSAGPGPRGP 141
               +  G  G G  GP
Sbjct: 246 GSPGYGGGRGGYGGGGP 262


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 44/122 (36%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GGG C            G+G+ G  ++   G   +++ S  +G  R G  GGGR    + 
Sbjct: 40  GGGAC--------GFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFA 91

Query: 66  QAGRGGGVCGR-GRGRGRGRGRGRGRGRGRGRPPSGGSG----LGGDGGGCGGGGSGGGG 120
             G GGG  G  G G G GRG G G G   G   +GG G     GG G   G GG G GG
Sbjct: 92  -GGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGG 150

Query: 121 AP 122
            P
Sbjct: 151 FP 152



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 42/132 (31%), Positives = 48/132 (36%), Gaps = 31/132 (23%)

Query: 65  KQAGRGGGVCGRGRGRGR-------------------GRGRGRGRGRGRGRPPSG----- 100
           +  G GGG CG   G G                      G  R  G G GR   G     
Sbjct: 35  RSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGY 94

Query: 101 GSGLGGD-GGGCGGG---GSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALP 156
           G G GG  GGG GGG   GSG GGA          G  GPG  G   +  G     P   
Sbjct: 95  GGGFGGSYGGGFGGGRGVGSGFGGA---GGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGF 151

Query: 157 PGWKKEEVIRKS 168
           PG  +E ++ +S
Sbjct: 152 PGGIQEVIVNQS 163



 Score = 35.4 bits (80), Expect = 0.062
 Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 16/113 (14%)

Query: 19  SAAGGSGA-----GGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGV 73
           S +G SG+     GG S    GG     + S  SG    G  G G G          G  
Sbjct: 514 STSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYG------GVSSGST 567

Query: 74  CGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGC---GGGG--SGGGGA 121
            GRG            R  G G      SG+G   G     GG G  SGGGG+
Sbjct: 568 GGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGS 620



 Score = 35.0 bits (79), Expect = 0.081
 Identities = 33/98 (33%), Positives = 38/98 (38%), Gaps = 4/98 (4%)

Query: 28  GDSAIEQGGQGSALAPSPVSGVRR-EGARGGGRGR-GRWKQAGRGGGVCGRGRGRGRGRG 85
           G+     G   SA+  S VS V    G+ G  RG  G    +G GG   G       G G
Sbjct: 491 GEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYG 550

Query: 86  RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGG--GGA 121
              G G G G   SG +G  G  G      SG   GGA
Sbjct: 551 VSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGA 588



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 4/95 (4%)

Query: 17  GESAAGGSG-AGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCG 75
           G S +G  G  GG S+    G G +       G    G+ GG    G ++ +  G  + G
Sbjct: 528 GVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGG 587

Query: 76  RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGG 110
            G       G G   G       SGGSG    GGG
Sbjct: 588 AGSISVSHSGMGSSSG---SIQTSGGSGYKSGGGG 619


>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
           [Homo sapiens]
          Length = 526

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 42/105 (40%), Positives = 49/105 (46%), Gaps = 15/105 (14%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GGG    + +   S+ GGSG G  +  + GG GS        G  ++    GGRGRG   
Sbjct: 172 GGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-------GYGQQDR--GGRGRG--- 219

Query: 66  QAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGG 110
             G GGG  G G G  R  G    RGRG GR   GG G G D GG
Sbjct: 220 --GSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMG-GSDRGG 261



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 28/44 (63%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 76  RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGG 119
           RG G GRG GRGRG   GRG    GGSG GG GG   GGG GGG
Sbjct: 377 RGGGNGRG-GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGG 419



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 32/76 (42%), Positives = 36/76 (47%), Gaps = 7/76 (9%)

Query: 53  GARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCG 112
           G  GGG   G+ + +   GG  G G G G     G G   G G+   GG G GG GGG G
Sbjct: 169 GGGGGGGNYGQDQSSMSSGG--GSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGG 226

Query: 113 GGGSG-----GGGAPR 123
           GGG G     GG  PR
Sbjct: 227 GGGGGYNRSSGGYEPR 242



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 28/47 (59%), Positives = 28/47 (59%), Gaps = 2/47 (4%)

Query: 78  RGRGRGRGRGRGRGRGRGRPPSGGSGLGGDG-GGCGGGGSGGGGAPR 123
           RG G GRG GRGRG   GR   GG G GG G GG   GG GGGG  R
Sbjct: 377 RGGGNGRG-GRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQR 422



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 26/164 (15%)

Query: 3   AHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREG--------- 53
           ++PG G    +Q    S +G  G+   S+     Q  + +  P  G +++          
Sbjct: 96  SYPGYG----QQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151

Query: 54  ARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR---GRGRGRGRG-RPPSGGSGLGG--- 106
            +G G+ + ++  +  GGG  G G   G+ +     G G G G G +  SGG G GG   
Sbjct: 152 PQGYGQ-QNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210

Query: 107 -DGGGCG-GGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGK 148
            D GG G GG  GGGG        +   S G  PRG      G+
Sbjct: 211 QDRGGRGRGGSGGGGGGGGG---GYNRSSGGYEPRGRGGGRGGR 251



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 44/137 (32%), Positives = 47/137 (34%), Gaps = 18/137 (13%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSA--------LAPSPVSGVRREGARGG 57
           G GR  P    G    GGSG GG      GG G            P+P         R  
Sbjct: 385 GRGRGGP-MGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNE 443

Query: 58  GRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRG-------RGRGRPPSG--GSGLGGDG 108
                  K  G GGG  G   G   G  R  GRG       RGRG    G  G   GGD 
Sbjct: 444 CNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDR 503

Query: 109 GGCGGGGSGGGGAPRRE 125
           GG G G     G  R++
Sbjct: 504 GGFGPGKMDSRGEHRQD 520



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 12/79 (15%)

Query: 84  RGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRA 143
           RG G GRG GRGR           GG  G GG GGGG+       FPSG  G G +    
Sbjct: 377 RGGGNGRG-GRGR-----------GGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAG 424

Query: 144 TESGKRMDCPALPPGWKKE 162
                   C  +   W+ E
Sbjct: 425 DWKCPNPTCENMNFSWRNE 443



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 49/174 (28%), Positives = 53/174 (30%), Gaps = 64/174 (36%)

Query: 17  GESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGG---- 72
           G +  GG G GG     +GG G              G   GG GRG +   G GGG    
Sbjct: 379 GGNGRGGRGRGGPMG--RGGYG--------------GGGSGGGGRGGFPSGGGGGGGQQR 422

Query: 73  ---------VC--------------------GRGRGRG---RGRGRGRGRGRGRGRPPSG 100
                     C                    G G G G    G   G  R  GRG    G
Sbjct: 423 AGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRG 482

Query: 101 G-SGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCP 153
           G  G GGD GG  GG  GG             G  GPG    R      R + P
Sbjct: 483 GYRGRGGDRGGFRGGRGGG-----------DRGGFGPGKMDSRGEHRQDRRERP 525



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 12/87 (13%)

Query: 12  PEQEEGESAAGGSGAGGDSAIEQ-GGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG 70
           P+ +      GGS  GG+   ++ GG+G         G  R G RG G  RG ++  GRG
Sbjct: 450 PKPDGPGGGPGGSHMGGNYGDDRRGGRG---------GYDRGGYRGRGGDRGGFR-GGRG 499

Query: 71  GGVCGRGRGRGRGRGRGRGRGRGRGRP 97
           GG  G G G G+   RG  R   R RP
Sbjct: 500 GGDRG-GFGPGKMDSRGEHRQDRRERP 525


>gi|154091020 leucine-rich repeats and calponin homology (CH) domain
           containing 2 [Homo sapiens]
          Length = 765

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 39/113 (34%), Positives = 49/113 (43%), Gaps = 16/113 (14%)

Query: 82  RGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGP 141
           +G G   G G   G   SGG G  G GGG  GGG GGGG     P+P P+    P P GP
Sbjct: 5   QGGGGNSGGGGCGGGGSSGGCGTAGGGGGGAGGGGGGGGGTLVVPIPVPTLFGQPFPNGP 64

Query: 142 RATESGKRMDCPALPPGWKKEEVIR---KSGLSAGKSDVYYFSPSGKKFRSKP 191
                      P  P   + +  +R   ++   AG S +   S SG+K R  P
Sbjct: 65  -----------PWNPGSLQPQHTVRSLDRALEEAGSSGI--LSLSGRKLRDFP 104



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 25/62 (40%), Positives = 26/62 (41%), Gaps = 19/62 (30%)

Query: 1  MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
          M A  GGG        G S  GG G GG S    GG G+A       G    GA GGG G
Sbjct: 1  MAASQGGG--------GNSGGGGCGGGGSS----GGCGTA-------GGGGGGAGGGGGG 41

Query: 61 RG 62
           G
Sbjct: 42 GG 43



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 15/41 (36%), Positives = 17/41 (41%)

Query: 6  GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPV 46
          GGG C      G     G G GG      GG G+ + P PV
Sbjct: 12 GGGGCGGGGSSGGCGTAGGGGGGAGGGGGGGGGTLVVPIPV 52


>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
           sapiens]
          Length = 378

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 41/95 (43%), Positives = 45/95 (47%), Gaps = 13/95 (13%)

Query: 40  ALAPSPVSGVRREGARGGGRGR--GRWKQAGRGGGVCGRG---RGRGRGRGRGRGRGRGR 94
           AL+   +     +  RGGG G   GR    G GGG  GRG    GRG G G G G  RG 
Sbjct: 201 ALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRG-GYGGGGGGSRGS 259

Query: 95  -GRPPSGGSGLGGDGGGCGGG------GSGGGGAP 122
            G    G +G GGDGG  GGG      G  GGG P
Sbjct: 260 YGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGP 294



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 15/113 (13%)

Query: 14  QEEGESAAGGSGAGGDSAIEQG------GQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
           ++E +SA    G GG S    G      G G         G R  G  GGG G  R    
Sbjct: 204 KQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGR--GGYGGGGGGSRGSYG 261

Query: 68  GRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
           G  GG  G G       G G   G G G    GG G GG G G  GGG GGGG
Sbjct: 262 GGDGGYNGFG-------GDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGG 307



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 43/129 (33%), Positives = 48/129 (37%), Gaps = 11/129 (8%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GGG        G    G +G GGD     GG G +       G    G +GGG G G   
Sbjct: 250 GGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGY 309

Query: 66  QAGRGGGVCGRGRGRGRGR----GRGRGRGRGRGRPPSGGSGLGGD------GGGCGGGG 115
                GG  G G   G G     G   G+ +    P  GGS  GG       GGG G GG
Sbjct: 310 DGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGS-FGGRSSGSPYGGGYGSGG 368

Query: 116 SGGGGAPRR 124
             GG   RR
Sbjct: 369 GSGGYGSRR 377



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 40/117 (34%), Positives = 42/117 (35%), Gaps = 24/117 (20%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
           GGG        G     G G GG      GG G         G    G  GG        
Sbjct: 233 GGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDG---------GYNGFGGDGGN------- 276

Query: 66  QAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGG--DGGGCGGGGSGGGG 120
             G G G   RG   G G G G  +G G G    GG G  G  +GG  GGG  GGGG
Sbjct: 277 -YGGGPGYSSRGGYGGGGPGYG-NQGGGYG----GGGGYDGYNEGGNFGGGNYGGGG 327



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 7/102 (6%)

Query: 22  GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGR-----GRWKQAGRGGGVCGR 76
           GG+  GG     +GG           G    G+ GGG G      G     G G G   R
Sbjct: 227 GGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSR 286

Query: 77  GRGRGRGRGRG-RGRGRGRGRPPSGGSGLGGDGGG-CGGGGS 116
           G   G G G G +G G G G    G +  G  GGG  GGGG+
Sbjct: 287 GGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGN 328


>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
          Length = 518

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 43/119 (36%), Positives = 54/119 (45%), Gaps = 13/119 (10%)

Query: 33  EQGGQGSALAPSPVS----------GVRREGARGGGRGRGRWKQ-AGRGGGVCGRGRGRG 81
           ++GG+ + + P P              ++ G RGGGRG        GRGG   G GRG G
Sbjct: 304 DRGGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRG-G 362

Query: 82  RGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
           RG     GRG GRG    GG   GG GGG GG   GG      +P  +  G +  G +G
Sbjct: 363 RGGYDHGGRGGGRGNKHQGGWTDGGSGGG-GGYQDGGYRDSGFQPGGYHGGHSSGGYQG 420



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 11/118 (9%)

Query: 6   GGGRCCPEQEEGESAAGGSGAGGDSAIEQGG-QGSALAPSPVSGVRREGA-RGGGRGRGR 63
           GGGR    + +G    GGSG GG    + GG + S   P    G    G  +GGG G  +
Sbjct: 372 GGGR--GNKHQGGWTDGGSGGGG--GYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGGFQ 427

Query: 64  WKQAGRGGGVCGRG-----RGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGS 116
              +  G G  G G     R +  G    RG GRG      G  G  G GGG GG GS
Sbjct: 428 TSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGS 485



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 38/110 (34%), Positives = 45/110 (40%), Gaps = 17/110 (15%)

Query: 12  PEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG-RGRWKQAGRG 70
           P+Q+ G     G G GG      GG+G                +GGGRG RG +   GRG
Sbjct: 329 PQQQTG---GRGGGRGGYEHSSYGGRGGH-------------EQGGGRGGRGGYDHGGRG 372

Query: 71  GGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
           GG   + +G     G G G G   G     G   GG  GG   GG  GGG
Sbjct: 373 GGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGG 422


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.140    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,213,177
Number of Sequences: 37866
Number of extensions: 1290777
Number of successful extensions: 34782
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 862
Number of HSP's successfully gapped in prelim test: 853
Number of HSP's that attempted gapping in prelim test: 10226
Number of HSP's gapped (non-prelim): 10357
length of query: 302
length of database: 18,247,518
effective HSP length: 102
effective length of query: 200
effective length of database: 14,385,186
effective search space: 2877037200
effective search space used: 2877037200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.