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Search of human proteins with 7662126
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662126 signal-induced proliferation-associated 1 like 1
[Homo sapiens]
(1804 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom... 3597 0.0
gi|112421013 signal-induced proliferation-associated 1 like 2 [H... 1571 0.0
gi|71143119 signal-induced proliferation-associated 1 like 3 [Ho... 1409 0.0
gi|206725526 signal-induced proliferation-associated protein 1 [... 639 0.0
gi|206725523 signal-induced proliferation-associated protein 1 [... 639 0.0
gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ... 231 5e-60
gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ... 231 5e-60
gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapi... 222 3e-57
gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi... 222 3e-57
gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapi... 222 3e-57
gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo sa... 218 3e-56
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2... 73 2e-12
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1... 73 2e-12
gi|118600961 akt substrate AS250 [Homo sapiens] 71 8e-12
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens] 65 8e-10
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens] 65 8e-10
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens] 65 8e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 63 3e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 62 5e-09
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 62 7e-09
gi|161016767 mucin 21 [Homo sapiens] 53 2e-06
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 50 2e-05
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens] 50 2e-05
gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 50 2e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens] 48 8e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 47 1e-04
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens] 47 1e-04
gi|83367077 mucin 16 [Homo sapiens] 46 3e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 44 0.001
gi|60097902 filaggrin [Homo sapiens] 44 0.001
>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
sapiens]
Length = 1804
Score = 3597 bits (9327), Expect = 0.0
Identities = 1804/1804 (100%), Positives = 1804/1804 (100%)
Query: 1 MTSLKRSQTERPLATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSE 60
MTSLKRSQTERPLATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSE
Sbjct: 1 MTSLKRSQTERPLATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSE 60
Query: 61 GSHHITSTPGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGS 120
GSHHITSTPGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGS
Sbjct: 61 GSHHITSTPGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGS 120
Query: 121 SVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITI 180
SVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITI
Sbjct: 121 SVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITI 180
Query: 181 SELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPTP 240
SELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPTP
Sbjct: 181 SELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPTP 240
Query: 241 TKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLR 300
TKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLR
Sbjct: 241 TKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLR 300
Query: 301 NAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTT 360
NAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTT
Sbjct: 301 NAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTT 360
Query: 361 TGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNE 420
TGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNE
Sbjct: 361 TGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNE 420
Query: 421 IGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRY 480
IGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRY
Sbjct: 421 IGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRY 480
Query: 481 IVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFR 540
IVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFR
Sbjct: 481 IVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFR 540
Query: 541 TSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLM 600
TSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLM
Sbjct: 541 TSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLM 600
Query: 601 KLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQ 660
KLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQ
Sbjct: 601 KLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQ 660
Query: 661 LDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGA 720
LDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGA
Sbjct: 661 LDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGA 720
Query: 721 QPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVF 780
QPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVF
Sbjct: 721 QPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVF 780
Query: 781 RDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASK 840
RDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASK
Sbjct: 781 RDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASK 840
Query: 841 KKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCS 900
KKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCS
Sbjct: 841 KKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCS 900
Query: 901 CRDVIGWTSTDTSLKIFYERGECVSVGSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNG 960
CRDVIGWTSTDTSLKIFYERGECVSVGSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNG
Sbjct: 901 CRDVIGWTSTDTSLKIFYERGECVSVGSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNG 960
Query: 961 LGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTV 1020
LGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTV
Sbjct: 961 LGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTV 1020
Query: 1021 KVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQ 1080
KVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQ
Sbjct: 1021 KVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQ 1080
Query: 1081 VPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMA 1140
VPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMA
Sbjct: 1081 VPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMA 1140
Query: 1141 LARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKS 1200
LARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKS
Sbjct: 1141 LARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKS 1200
Query: 1201 TPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRL 1260
TPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRL
Sbjct: 1201 TPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRL 1260
Query: 1261 MRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQ 1320
MRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQ
Sbjct: 1261 MRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQ 1320
Query: 1321 GTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETE 1380
GTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETE
Sbjct: 1321 GTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETE 1380
Query: 1381 SHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSA 1440
SHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSA
Sbjct: 1381 SHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSA 1440
Query: 1441 RSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFM 1500
RSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFM
Sbjct: 1441 RSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFM 1500
Query: 1501 DTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKF 1560
DTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKF
Sbjct: 1501 DTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKF 1560
Query: 1561 HALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYP 1620
HALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYP
Sbjct: 1561 HALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYP 1620
Query: 1621 SLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWS 1680
SLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWS
Sbjct: 1621 SLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWS 1680
Query: 1681 NLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSSPTLASK 1740
NLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSSPTLASK
Sbjct: 1681 NLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSSPTLASK 1740
Query: 1741 VDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNT 1800
VDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNT
Sbjct: 1741 VDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNT 1800
Query: 1801 IDMS 1804
IDMS
Sbjct: 1801 IDMS 1804
>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
sapiens]
Length = 1722
Score = 1571 bits (4067), Expect = 0.0
Identities = 929/1874 (49%), Positives = 1185/1874 (63%), Gaps = 227/1874 (12%)
Query: 1 MTSLKRSQTERPLATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSV-MAPVGPPRS 59
M+ ++SQ E+ RAS D + +DD++ R+F++ NG++G + + +
Sbjct: 1 MSDPRQSQEEKH-KLGRASSKFKDPPRIMQSDDYFARKFKAINGNMGPTTSLNASNSNET 59
Query: 60 EGSHHITSTPGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQG 119
G TP VPKMGVRAR+++WPP+K+ KE + + + S S S +S + G
Sbjct: 60 GGGGPANGTPAVPKMGVRARVSEWPPKKDCSKELT--CKALWESRSQTSYESITSVLQNG 117
Query: 120 SSVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDIT 179
S L + +++++ + + + SP++ L IRQRSNSD+T
Sbjct: 118 QSDQSEGQQDEQLDL------------DFVEAKYTIGDIFVHSPQRGLHPIRQRSNSDVT 165
Query: 180 ISELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSD-RGP 238
IS++D + + + TG +LHREYGSTSSID+QG SGE+FF +L+GY+ + D +
Sbjct: 166 ISDIDAEDVLDQNAVNPNTGAALHREYGSTSSIDRQGLSGENFFAMLRGYRVENYDHKAM 225
Query: 239 TPTKLSDFL---------------ITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLK 283
P +F I+ G LD +D L + ++R+KP K
Sbjct: 226 VPFGFPEFFRCDPAISPSLHAAAQISRGEFVRISGLDYVDSA------LLMGRDRDKPFK 279
Query: 284 RRSKSETGDSSIFRKLRNAKGEE--LGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILF 341
RR KSE+ ++S+FRKLR K E +S+LE++R E +RPW C +CFAHYDVQSILF
Sbjct: 280 RRLKSESVETSLFRKLRTVKSEHETFKFTSELEESRLERGIRPWNCQRCFAHYDVQSILF 339
Query: 342 DLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMD 401
++NEA+ R NV KR+N TTGASAA+ + P + + SP+GS EDLNSK +L D
Sbjct: 340 NINEAMATRANVGKRKNITTGASAASQTQM---PTGQTGNCESPLGSKEDLNSKENLDAD 396
Query: 402 QGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVA 461
+GD KSN+LV+SCPYFRNE GGEG+R+I+LS++NS SFS ES SFES+LSSHCTNAGV+
Sbjct: 397 EGDGKSNDLVLSCPYFRNETGGEGDRRIALSRANSSSFSSGESCSFESSLSSHCTNAGVS 456
Query: 462 VLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRRE 521
VLEVP+EN +H ++VKRYI+EH+DLGAYYYRKFFY KEH NYFG DENLGPVAVSIRRE
Sbjct: 457 VLEVPRENQPIHREKVKRYIIEHIDLGAYYYRKFFYGKEHQNYFGIDENLGPVAVSIRRE 516
Query: 522 KPDEMKEN-GSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPE 580
K ++ KE GS +NYR+ FRTSEL TLRG++LEDAIPSTA+H TARGLPLKEVLE+V+PE
Sbjct: 517 KVEDAKEKEGSQFNYRVAFRTSELTTLRGAILEDAIPSTARHGTARGLPLKEVLEYVIPE 576
Query: 581 LNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEE 640
L++QCLR A N+PKV+EQL+KLDEQGL++Q K+GI+YCKAGQSTEEEMYNNE+AGPAFEE
Sbjct: 577 LSIQCLRQASNSPKVSEQLLKLDEQGLSFQHKIGILYCKAGQSTEEEMYNNETAGPAFEE 636
Query: 641 FLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQL 700
FL LLG+RVRLKGF KYRAQLD KTDSTGTHSLYTTYKDYE+MFHVST+LPY PNN+QQL
Sbjct: 637 FLDLLGQRVRLKGFSKYRAQLDNKTDSTGTHSLYTTYKDYELMFHVSTLLPYMPNNRQQL 696
Query: 701 LRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRD 760
LRKRHIGNDIVTIVFQEPGA PF+PK+IRSHFQHVFVIV+VHNPC+++VCYSV V+RS+D
Sbjct: 697 LRKRHIGNDIVTIVFQEPGALPFTPKSIRSHFQHVFVIVKVHNPCTENVCYSVGVSRSKD 756
Query: 761 VPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKN 820
VP FGPPIPKGVTFPKS VFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAE
Sbjct: 757 VPPFGPPIPKGVTFPKSAVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAENF 816
Query: 821 VTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGI 880
VT +D S KF FI+L +KKKEK KP A L S+GAI+W V A D+ ++ +++CLLGI
Sbjct: 817 VTTATVDTSVKFSFITLGAKKKEKVKPRKDAHLFSIGAIMWHVIARDFGQSADIECLLGI 876
Query: 881 SNEFIVLIEQETKSVVFNCSCRDVIGWTSTDTSLKIFYERGECVSVGSFIN-IEEIKEIV 939
SNEFI+LIE+++K+VVFNCSCRDVIGWTS S+K+FYERGECV + S N E+I+EIV
Sbjct: 877 SNEFIMLIEKDSKNVVFNCSCRDVIGWTSGLVSIKVFYERGECVLLSSVDNCAEDIREIV 936
Query: 940 KRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICK 999
+RL V++GCE+VEMTLRRNGLGQLGFHVN+EGIVADVEP+G+AW+AGLRQGSRLVEICK
Sbjct: 937 QRLVIVTRGCETVEMTLRRNGLGQLGFHVNFEGIVADVEPFGFAWKAGLRQGSRLVEICK 996
Query: 1000 VAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKM-NEGVSYEF 1058
VAVATL+HEQMIDLLRTSVTVKVVII PHDD +PRR CSE R+P++EYK+ +EG E+
Sbjct: 997 VAVATLTHEQMIDLLRTSVTVKVVIIQPHDDGSPRRGCSELCRIPMVEYKLDSEGTPCEY 1056
Query: 1059 KFPFRNNNKWQRNASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPP-----PERAANIPR 1113
K PFR N W R VP+ P+ SR + G P + A IPR
Sbjct: 1057 KTPFRRNTTWHR----------VPTPALQPL-SRASPIPGTPDRLPCQQLLQQAQAAIPR 1105
Query: 1114 SISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSDTGSVG-GTYRQKSMP 1172
S S D R+L G+ R+SPSN SSSSD G G G +R +
Sbjct: 1106 STSFD-----RKLPDGT----------------RSSPSNQSSSSDPGPGGSGPWRPQVGY 1144
Query: 1173 EGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQ 1232
+G +SP ++ Q GSG R + +E
Sbjct: 1145 DGC----QSPLLLEHQ-------GSGPLECDGARERED------------------TMEA 1175
Query: 1233 HEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGH-SDSHYSSHSSSNTLS 1291
+ E H P SKVL +++E R +++D SPNK H D SSHSSSNTLS
Sbjct: 1176 SRHPETKWHGPP-SKVLGSYKE----RALQKDGSCKDSPNKLSHIGDKSCSSHSSSNTLS 1230
Query: 1292 SNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDT------TSYGPSHGSTASLGA 1345
SN SS D+ + GD + EL Y++G S DSGIDT T GP H L
Sbjct: 1231 SNTSSNSDDKHFGSGDLMDPELLGLTYIKGASTDSGIDTAPCMPATILGPVH-----LAG 1285
Query: 1346 ATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGST 1405
+ S S A W +++V D E + +H + S
Sbjct: 1286 SRSLIHSR------AEQWADAADVSGPDD--------------EPAKLYSVHGYASTISA 1325
Query: 1406 PLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSS 1465
E S +++ +SH+S S HS SP S S + + S SS
Sbjct: 1326 GSAAEGSMGDLSEISSHSS--GSHHSGSPSAHCSKSSGSLD-----SSKVYIVSHSSGQQ 1378
Query: 1466 SSSGPRSFYPRQGATSKYLIGWKKPEGT--------------INSVGFMDTRKRHQS-DG 1510
Y RQGA +KY+IGWKK EG+ + + M T +HQ+ G
Sbjct: 1379 VPGSMSKPYHRQGAVNKYVIGWKKSEGSPPPEEPEVTECPGMYSEMDVMSTATQHQTVVG 1438
Query: 1511 NEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESP-TPESQKSFKFHALSSPQSP 1569
+ +A T+ S +ED KL+ +SP E ++ F F+ SP
Sbjct: 1439 DAVAETQHVLS----------------KEDFLKLMLPDSPLVEEGRRKFSFYGNLSP--- 1479
Query: 1570 FPSTPTSRRALHRTLSDESIYNSQR-EHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPL 1628
RR+L+RTLSDESI +++R F +SR+S+LDQALPND+LFS+T P P
Sbjct: 1480 -------RRSLYRTLSDESICSNRRGSSFGSSRSSVLDQALPNDILFSTTPPYHSTLPPR 1532
Query: 1629 RRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKA 1688
P+ ++G SL EF SD SL+D + DPGLMPLPDTA LDW++LVDAA+A
Sbjct: 1533 AHPAPSMG--SLRNEFWFSDGSLSD-----KSKCADPGLMPLPDTATGLDWTHLVDAARA 1585
Query: 1689 YE-------------------VQRASFFAASDENH-RPLSAASNSDQLEDQALAQMKPYS 1728
+E + ASF +D H + L A D + +
Sbjct: 1586 FEGLDSDEELGLLCHHTSYLDQRVASFCTLTDMQHGQDLEGAQELPLCVDPGSGKEFMDT 1645
Query: 1729 SSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASD 1788
+ + S L KV+QLE +L+ L+ DL+KEK+DKA LQAEVQHLR+DN+RLQEESQ A+
Sbjct: 1646 TGERSPSPLTGKVNQLELILRQLQTDLRKEKQDKAVLQAEVQHLRQDNMRLQEESQTATA 1705
Query: 1789 KLKKFTEWVFNTID 1802
+L+KFTEW F TID
Sbjct: 1706 QLRKFTEWFFTTID 1719
>gi|71143119 signal-induced proliferation-associated 1 like 3 [Homo
sapiens]
Length = 1781
Score = 1409 bits (3646), Expect = 0.0
Identities = 877/1841 (47%), Positives = 1131/1841 (61%), Gaps = 140/1841 (7%)
Query: 13 LATDRASVVGTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSEGSHHITST---- 68
LA + VG D P HT D+ F +QNGS+ P+G + + T+T
Sbjct: 14 LAASCGARVG-DVLPGPHTGDYAPLGFWAQNGSMSQ----PLGESPATATATATATTRPS 68
Query: 69 ---PGVPKMGVRARIADWPPRKENIKESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLN 125
P +PKMGVRAR+ADWPP++E ++E S S +T + + S Q +
Sbjct: 69 PTTPAMPKMGVRARVADWPPKREALREHSNPSPSQDTDGTKATKMAHSMRSIQNGQPPTS 128
Query: 126 SNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDV 185
+ S+ K+ + +++ E D +P SP +A +R RS+S+IT+SE D
Sbjct: 129 TPASSGSKAFHRLSRRRSKDVEFQDG-------WPRSPGRAFLPLRHRSSSEITLSECDA 181
Query: 186 DSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSD-RG-PTPTKL 243
+ E + L REYGSTSSID QG +SFFD+L ++ ++ D RG T+L
Sbjct: 182 EDAGEPRGARHTGALPLFREYGSTSSIDVQGMPEQSFFDILNEFRSEQPDARGCQALTEL 241
Query: 244 -----SDFLITGGGKGSGFSLD---VIDGPISQRENLRLFKEREKPLKRRSKSETGDSSI 295
L+ GGG G S + D + + K R+KP + +T DSSI
Sbjct: 242 LRADPGPHLMGGGGGAKGDSHNGQPAKDSLLPLQPTKEKEKARKKPARGLGGGDTVDSSI 301
Query: 296 FRKLRNAKGE-ELGKS-SDLEDNRSE-DSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHN 352
FRKLR++K E E G+S + ++ RS ++ RPW C K FAH+DVQS+LFDLNEA NR +
Sbjct: 302 FRKLRSSKPEGEAGRSPGEADEGRSPPEASRPWVCQKSFAHFDVQSMLFDLNEAAANRVS 361
Query: 353 VIKRRNTTTGASAAAVASLVSG---PLSHSASFSSP-MGSTEDLNSKGSLSMDQGDDKSN 408
V +RRNTTTGASAA+ AS ++ +HS P STEDLN K +L D GDD SN
Sbjct: 362 VSQRRNTTTGASAASAASAMASLTASRAHSLGGLDPAFTSTEDLNCKENLEQDLGDDNSN 421
Query: 409 ELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKE 468
+L++SCP+FRNEIGGE ER +S S+++ GS S E E LS++ TNA ++VLEVPKE
Sbjct: 422 DLLLSCPHFRNEIGGECERNVSFSRASVGSPSSGEGHLAEPALSAYRTNASISVLEVPKE 481
Query: 469 NLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKE 528
R ++Y +EHVDLGA YY+ +F KEH NYFG DE LGPVAVSI+REK ++ KE
Sbjct: 482 QQRTQ-SRPRQYSIEHVDLGARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKE 540
Query: 529 NGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRL 588
+G Y YRIIFRT EL+TLRGS+LEDA P+ KH T RGLPLK+ LE+V+PELN+ CLRL
Sbjct: 541 HGPQYQYRIIFRTRELITLRGSILEDATPTATKHGTGRGLPLKDALEYVIPELNIHCLRL 600
Query: 589 AFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGER 648
A NTPKVTEQL+KLDEQGL + KVGI+YCKAGQS+EEEMYNNE AGPAFEEFL L+GE+
Sbjct: 601 ALNTPKVTEQLLKLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEK 660
Query: 649 VRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGN 708
V LKGF KY AQLD KTDSTGTHSLYT Y+DYEIMFHVST+LPYTPNN+QQLLRKRHIGN
Sbjct: 661 VCLKGFTKYAAQLDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGN 720
Query: 709 DIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPI 768
DIVTI+FQEPGA PF+PKNIRSHFQHVF+IVRVHNPC+D+VCYS+AVTRS+D P FGPPI
Sbjct: 721 DIVTIIFQEPGALPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPI 780
Query: 769 PKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDP 828
P G TF KS+VFRDFLLAKVINAENAAHKS+KF MATRTRQEYLKDLAE V+NTPID
Sbjct: 781 PSGTTFRKSDVFRDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAENCVSNTPIDS 840
Query: 829 SGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAEDYNKAMELDCLLGISNEFIVLI 888
+GKF ISL SKKKEK+K GAE S GAI W V A+DY + +E+DC+LGISNEF+VL+
Sbjct: 841 TGKFNLISLTSKKKEKTKARAGAEQHSAGAIAWRVVAQDYAQGVEIDCILGISNEFVVLL 900
Query: 889 EQETKSVVFNCSCRDVIGWTSTDTSLKIFYERGECVSV-GSFINIEEIKEIVKRLQFVSK 947
+ TK VVFNC C DVIGWT ++LKIFY RG+ + + + ++E+I+EIV+RL+ ++
Sbjct: 901 DLRTKEVVFNCYCGDVIGWTPDSSTLKIFYGRGDHIFLQATEGSVEDIREIVQRLKVMTS 960
Query: 948 GCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSH 1007
G E+V+MTLRRNGLGQLGFHV Y+G VA+VE YG+AWQAGLRQGSRLVEICKVAV TL+H
Sbjct: 961 GWETVDMTLRRNGLGQLGFHVKYDGTVAEVEDYGFAWQAGLRQGSRLVEICKVAVVTLTH 1020
Query: 1008 EQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKM-NEGVSYEFKFPFRNNN 1066
+QMIDLLRTSVTVKVVIIPP +D TPRR ETY M E K E ++ + P+R+N
Sbjct: 1021 DQMIDLLRTSVTVKVVIIPPFEDGTPRRGWPETYDMNTSEPKTEQESITPGGRPPYRSNA 1080
Query: 1067 KWQRNASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPL-ERR 1125
WQ + H+ S+ +P T G P ++ +P + +PL +R
Sbjct: 1081 PWQW-SGPASHNSLPASKWATPTT----PGHAQSLSRPLKQTPIVP---FRESQPLHSKR 1132
Query: 1126 LSPGSDIYVTVSSMALARSQCRNSPSNLSSSSDTGSVGGTY-RQKSMPEGFGVSRRSPAS 1184
+ TVS R PS S S GS TY R K PE + + S
Sbjct: 1133 PVSFPETPYTVSPAGADRVPPYRQPS--GSFSTPGS--ATYVRYKPSPERYTAAPHPLLS 1188
Query: 1185 IDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPA 1244
+D + D SG S+ S++S ++ + EP H+PA
Sbjct: 1189 LD-PHFSHDGTSSGDSSSGGLTSQESTMER-------------------QKPEPLWHVPA 1228
Query: 1245 VSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWY 1304
+++ S + RQD SPN+ + YSSHSSSNTLSSNASS+HSD++W+
Sbjct: 1229 QARLSAIAGSSGNKHPSRQDAAGKDSPNRHSKGEPQYSSHSSSNTLSSNASSSHSDDRWF 1288
Query: 1305 DG-DRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLW 1363
D D E E + + +G S+DSGIDTT Y S+ S + +PR P K P
Sbjct: 1289 DPLDPLEPEQDPLS--KGGSSDSGIDTTLY----TSSPSCMSLAKAPR--PAKPHKPP-- 1338
Query: 1364 HSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTF------SIN 1417
S + R SH DR+ E S + + +S+ L S+
Sbjct: 1339 --GSMGLCGGGREAAGRSHHADRRREVSPAPAVAGQSKGYRPKLYSSGSSTPTGLAGGSR 1396
Query: 1418 DAASHTSTMSSRHSASPVVF-TSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPR 1476
D S M SR V+ T++ +P+ PSQLA S S+S P+SF+ +
Sbjct: 1397 DPPRQPSDMGSRVGYPAQVYKTASAETPR-------PSQLAQP-SPFQLSASVPKSFFSK 1448
Query: 1477 QGATSKYLIGWKK-PEGTINSVGFMDTRKRHQSD-GNEIAHTRLRASTRDLRASPKPTSK 1534
Q +K+ GWK+ E + F D +K+ ++ N RLRAS RDLR SP+ K
Sbjct: 1449 QPVRNKHPTGWKRTEEPPPRPLPFSDPKKQVDTNTKNVFGQPRLRASLRDLR-SPRKNYK 1507
Query: 1535 STIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQR 1594
STIE+DLKKLI +++ PE ++ + QSP ++ L RTLSDES+ + +R
Sbjct: 1508 STIEDDLKKLIIMDNLGPEQER-------DTGQSP-------QKGLQRTLSDESLCSGRR 1553
Query: 1595 EHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRR--------------PSYTLGMKSL 1640
E F S A L+ LP+DVLF+ST +LP RR P+ G
Sbjct: 1554 EPSFASPAG-LEPGLPSDVLFTSTCAFPSSTLPARRQHQHPHPPVGPGATPAAGSGFPEK 1612
Query: 1641 HGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRA-SFFAA 1699
SAS+ SL D ++ + + DPGLMPLPDTAA L+WS+LV+AAKAYEVQRA S F+
Sbjct: 1613 KSTISASELSLADGRDRPLRRL-DPGLMPLPDTAAGLEWSSLVNAAKAYEVQRAVSLFSL 1671
Query: 1700 SDENHRPLSAASNSDQLEDQALAQMKPY-----SSSKDSSPTLASKVDQLEGMLKMLRED 1754
+D P ++S +L + P + S++ L KV QLE MLK L D
Sbjct: 1672 NDPALSPDIPPAHSPVHSHLSLERGPPTPRTTPTMSEEPPLDLTGKVYQLEVMLKQLHTD 1731
Query: 1755 LKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTE 1795
L+KEK+DK LQ+EV LR++N RLQEESQ AS++L+KF E
Sbjct: 1732 LQKEKQDKVVLQSEVASLRQNNQRLQEESQAASEQLRKFAE 1772
>gi|206725526 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 639 bits (1647), Expect = 0.0
Identities = 394/920 (42%), Positives = 526/920 (57%), Gaps = 126/920 (13%)
Query: 319 EDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSH 378
E + P P+ FAHYDVQS+LFD A G SH
Sbjct: 104 EPAFPPVLEPRWFAHYDVQSLLFDW-------------------------APRSQGMGSH 138
Query: 379 SASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGS 438
S + S + S ED + S++L+ P F E+GGEGE +
Sbjct: 139 SEASSGTLASAEDQAA------------SSDLLHGAPGFVCELGGEGELGLG-------- 178
Query: 439 FSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQ 498
G S L NA V++LE P+ +R Y +EH DLGA YYRK+FY
Sbjct: 179 --GPASPPVPPALP----NAAVSILEEPQ-------NRTSAYSLEHADLGAGYYRKYFYG 225
Query: 499 KEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPS 558
KEH N+FG DE+LGPVAVS+RRE+ E G+ ++YR+I RT++L TLRG++ EDA+P
Sbjct: 226 KEHQNFFGMDESLGPVAVSLRREEK-EGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPP 284
Query: 559 TAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYC 618
RGL +++LEHV P+L+ CLRL +PKV L+ LDEQ L++Q+KVGI+YC
Sbjct: 285 ----GPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYC 340
Query: 619 KAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYK 678
+AGQ +EEEMYNN+ AGPAF +FL LLG+ VRLKGFE YRAQLDTKTDSTGTHSLYTTY+
Sbjct: 341 RAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQ 400
Query: 679 DYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVI 738
D+EIMFHVSTMLPYTPNN+QQLLRKRHIGNDIVTIVFQEPG++PF P IRSHFQHVF++
Sbjct: 401 DHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLV 460
Query: 739 VRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPK-GVTFPKSNVFRDFLLAKVINAENAAHK 797
VR H PC+ Y VAV+R++D P+FGP +P G F + FR FLLAK +N E AA
Sbjct: 461 VRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPFAANADFRAFLLAKALNGEQAAGH 520
Query: 798 SEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMG 857
+ +F AMATRTRQ+YL+DLA VT T +D + +F SL +++ + PGAEL + G
Sbjct: 521 ARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRAAPRG-PGAELQAAG 579
Query: 858 AIVWAVRA-----------EDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCSCRDVIG 906
++VW VRA + +E+ CLLGIS E +VL+ VVFNC+CRDV+
Sbjct: 580 SLVWGVRAAPGARVAAGAQASGPEGIEVPCLLGISAEALVLVAPRDGRVVFNCACRDVLA 639
Query: 907 WTSTDTSLKIFYERGECVSV---GSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNGLGQ 963
WT ++ L +++ RGE +++ GS + + E+V RLQ VS+GCE+ E+ L R+G G+
Sbjct: 640 WTFSEQQLDLYHGRGEAITLRFDGS--PGQAVGEVVARLQLVSRGCETRELALPRDGQGR 697
Query: 964 LGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVV 1023
LGF V+ EG V VE + +A AGLR G+RL+ +C + +L E LLR++ V V
Sbjct: 698 LGFEVDAEGFVTHVERFTFAETAGLRPGARLLRVCGQTLPSLRPEAAAQLLRSAPKVCVT 757
Query: 1024 IIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQVPS 1083
++PP + PRRS SE Y + + E R + P +V
Sbjct: 758 VLPPDESGRPRRSFSELYTLSLQEP--------------------SRRGAPDPVQDEVQG 797
Query: 1084 QVQSPMTSR-LNAGKGDGKMPP------PERAANI-------PRSISSDGRPLERRLSPG 1129
P T + L+ DG PP ER + PRS SD P+ +P
Sbjct: 798 VTLLPTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPD 857
Query: 1130 SDIYVTVS-SMALARSQ---CRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
+ T S+ A S+ ++ P + S S D G+ R +P + SI
Sbjct: 858 LLLATTAKPSVPSADSETPLTQDRPGSPSGSEDKGNPAPELRASFLPRTLSLRN----SI 913
Query: 1186 DRQNTQSDIGGSGKSTPSWQ 1205
R +++ GSG WQ
Sbjct: 914 SRIMSEA---GSGTLEDEWQ 930
Score = 62.8 bits (151), Expect = 3e-09
Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 35/239 (14%)
Query: 1574 PTSRRALHRTLSDESI------YNSQREHFFTS------RASLLDQA--LPN---DVLFS 1616
PT+++ LH L D +R F S R+SL D+A LPN D+L +
Sbjct: 802 PTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLA 861
Query: 1617 STY-PSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAA 1675
+T PS+P + S T + G S S E + P P+ LP T +
Sbjct: 862 TTAKPSVPSA-----DSETPLTQDRPGSPSGS--------EDKGNPAPELRASFLPRTLS 908
Query: 1676 DLDW-SNLVDAAKAYEVQ---RASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSK 1731
+ S ++ A + ++ +A AS N S + + + + P S ++
Sbjct: 909 LRNSISRIMSEAGSGTLEDEWQAISEIASTCNTILESLSREGQPIPESGDPKGTPKSDAE 968
Query: 1732 DSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKL 1790
L+ KV LE ML+ L+EDL+KEK D+A L+ EV+ LR +N RLQ ES++A+ +L
Sbjct: 969 PEPGNLSEKVSHLESMLRKLQEDLQKEKADRAALEEEVRSLRHNNRRLQAESESAATRL 1027
>gi|206725523 signal-induced proliferation-associated protein 1 [Homo
sapiens]
Length = 1042
Score = 639 bits (1647), Expect = 0.0
Identities = 394/920 (42%), Positives = 526/920 (57%), Gaps = 126/920 (13%)
Query: 319 EDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSH 378
E + P P+ FAHYDVQS+LFD A G SH
Sbjct: 104 EPAFPPVLEPRWFAHYDVQSLLFDW-------------------------APRSQGMGSH 138
Query: 379 SASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGS 438
S + S + S ED + S++L+ P F E+GGEGE +
Sbjct: 139 SEASSGTLASAEDQAA------------SSDLLHGAPGFVCELGGEGELGLG-------- 178
Query: 439 FSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQ 498
G S L NA V++LE P+ +R Y +EH DLGA YYRK+FY
Sbjct: 179 --GPASPPVPPALP----NAAVSILEEPQ-------NRTSAYSLEHADLGAGYYRKYFYG 225
Query: 499 KEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPS 558
KEH N+FG DE+LGPVAVS+RRE+ E G+ ++YR+I RT++L TLRG++ EDA+P
Sbjct: 226 KEHQNFFGMDESLGPVAVSLRREEK-EGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPP 284
Query: 559 TAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYC 618
RGL +++LEHV P+L+ CLRL +PKV L+ LDEQ L++Q+KVGI+YC
Sbjct: 285 ----GPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYC 340
Query: 619 KAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYK 678
+AGQ +EEEMYNN+ AGPAF +FL LLG+ VRLKGFE YRAQLDTKTDSTGTHSLYTTY+
Sbjct: 341 RAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQ 400
Query: 679 DYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVI 738
D+EIMFHVSTMLPYTPNN+QQLLRKRHIGNDIVTIVFQEPG++PF P IRSHFQHVF++
Sbjct: 401 DHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLV 460
Query: 739 VRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPK-GVTFPKSNVFRDFLLAKVINAENAAHK 797
VR H PC+ Y VAV+R++D P+FGP +P G F + FR FLLAK +N E AA
Sbjct: 461 VRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPFAANADFRAFLLAKALNGEQAAGH 520
Query: 798 SEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMG 857
+ +F AMATRTRQ+YL+DLA VT T +D + +F SL +++ + PGAEL + G
Sbjct: 521 ARQFHAMATRTRQQYLQDLATNEVTTTSLDSASRFGLPSLGGRRRAAPRG-PGAELQAAG 579
Query: 858 AIVWAVRA-----------EDYNKAMELDCLLGISNEFIVLIEQETKSVVFNCSCRDVIG 906
++VW VRA + +E+ CLLGIS E +VL+ VVFNC+CRDV+
Sbjct: 580 SLVWGVRAAPGARVAAGAQASGPEGIEVPCLLGISAEALVLVAPRDGRVVFNCACRDVLA 639
Query: 907 WTSTDTSLKIFYERGECVSV---GSFINIEEIKEIVKRLQFVSKGCESVEMTLRRNGLGQ 963
WT ++ L +++ RGE +++ GS + + E+V RLQ VS+GCE+ E+ L R+G G+
Sbjct: 640 WTFSEQQLDLYHGRGEAITLRFDGS--PGQAVGEVVARLQLVSRGCETRELALPRDGQGR 697
Query: 964 LGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVV 1023
LGF V+ EG V VE + +A AGLR G+RL+ +C + +L E LLR++ V V
Sbjct: 698 LGFEVDAEGFVTHVERFTFAETAGLRPGARLLRVCGQTLPSLRPEAAAQLLRSAPKVCVT 757
Query: 1024 IIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQVPS 1083
++PP + PRRS SE Y + + E R + P +V
Sbjct: 758 VLPPDESGRPRRSFSELYTLSLQEP--------------------SRRGAPDPVQDEVQG 797
Query: 1084 QVQSPMTSR-LNAGKGDGKMPP------PERAANI-------PRSISSDGRPLERRLSPG 1129
P T + L+ DG PP ER + PRS SD P+ +P
Sbjct: 798 VTLLPTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPD 857
Query: 1130 SDIYVTVS-SMALARSQ---CRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
+ T S+ A S+ ++ P + S S D G+ R +P + SI
Sbjct: 858 LLLATTAKPSVPSADSETPLTQDRPGSPSGSEDKGNPAPELRASFLPRTLSLRN----SI 913
Query: 1186 DRQNTQSDIGGSGKSTPSWQ 1205
R +++ GSG WQ
Sbjct: 914 SRIMSEA---GSGTLEDEWQ 930
Score = 62.8 bits (151), Expect = 3e-09
Identities = 72/239 (30%), Positives = 112/239 (46%), Gaps = 35/239 (14%)
Query: 1574 PTSRRALHRTLSDESI------YNSQREHFFTS------RASLLDQA--LPN---DVLFS 1616
PT+++ LH L D +R F S R+SL D+A LPN D+L +
Sbjct: 802 PTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSLSPRSSLSDEAPVLPNTTPDLLLA 861
Query: 1617 STY-PSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAA 1675
+T PS+P + S T + G S S E + P P+ LP T +
Sbjct: 862 TTAKPSVPSA-----DSETPLTQDRPGSPSGS--------EDKGNPAPELRASFLPRTLS 908
Query: 1676 DLDW-SNLVDAAKAYEVQ---RASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSK 1731
+ S ++ A + ++ +A AS N S + + + + P S ++
Sbjct: 909 LRNSISRIMSEAGSGTLEDEWQAISEIASTCNTILESLSREGQPIPESGDPKGTPKSDAE 968
Query: 1732 DSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKL 1790
L+ KV LE ML+ L+EDL+KEK D+A L+ EV+ LR +N RLQ ES++A+ +L
Sbjct: 969 PEPGNLSEKVSHLESMLRKLQEDLQKEKADRAALEEEVRSLRHNNRRLQAESESAATRL 1027
>gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2
[Homo sapiens]
Length = 715
Score = 231 bits (589), Expect = 5e-60
Identities = 134/335 (40%), Positives = 190/335 (56%), Gaps = 31/335 (9%)
Query: 492 YRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTS-----ELMT 546
YR+ F K+H N++ +LG + +S++ E+ + G Y R+I R+ E +
Sbjct: 142 YRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKLKTVHERIP 195
Query: 547 LRGSVLEDAIPSTAKH--STARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDE 604
L G ++P AK A GL VL PK ++ ++ DE
Sbjct: 196 LAGLSKLPSVPQIAKAFCDDAVGLRFNPVLY-----------------PKASQMIVSYDE 238
Query: 605 QGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTK 664
+N K G++Y KA Q+ EEE++ N PAF+EFL LLG+ + L+ F+ +R LD
Sbjct: 239 HEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVT 298
Query: 665 TDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFS 724
TG S+YTT++D EIMFHVST LP+T + QQL RKRHIGNDIV I+FQE PF
Sbjct: 299 HGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFV 357
Query: 725 PKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFL 784
P I S+F H +++V+V P +++ Y V+VT DVP+FGPP+P F K FR+FL
Sbjct: 358 PDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFL 417
Query: 785 LAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEK 819
L K+ NAENA KS+KF + RTR L +L ++
Sbjct: 418 LTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDE 452
>gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1
[Homo sapiens]
Length = 730
Score = 231 bits (589), Expect = 5e-60
Identities = 134/335 (40%), Positives = 190/335 (56%), Gaps = 31/335 (9%)
Query: 492 YRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTS-----ELMT 546
YR+ F K+H N++ +LG + +S++ E+ + G Y R+I R+ E +
Sbjct: 157 YRRHFLGKDHLNFYCTGSSLGNLILSVKCEEAE-----GIEY-LRVILRSKLKTVHERIP 210
Query: 547 LRGSVLEDAIPSTAKH--STARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDE 604
L G ++P AK A GL VL PK ++ ++ DE
Sbjct: 211 LAGLSKLPSVPQIAKAFCDDAVGLRFNPVLY-----------------PKASQMIVSYDE 253
Query: 605 QGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTK 664
+N K G++Y KA Q+ EEE++ N PAF+EFL LLG+ + L+ F+ +R LD
Sbjct: 254 HEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVT 313
Query: 665 TDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFS 724
TG S+YTT++D EIMFHVST LP+T + QQL RKRHIGNDIV I+FQE PF
Sbjct: 314 HGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENT-PFV 372
Query: 725 PKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFL 784
P I S+F H +++V+V P +++ Y V+VT DVP+FGPP+P F K FR+FL
Sbjct: 373 PDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGPPLPSPPVFQKGPEFREFL 432
Query: 785 LAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEK 819
L K+ NAENA KS+KF + RTR L +L ++
Sbjct: 433 LTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDE 467
>gi|224809582 RAP1 GTPase activating protein isoform c [Homo
sapiens]
Length = 663
Score = 222 bits (565), Expect = 3e-57
Identities = 128/331 (38%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 489 AYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLR 548
A YRK F KEH+NY+ D LG + S++ + G + R++ RT +
Sbjct: 87 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRT------K 134
Query: 549 GSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLN 608
D IP + + + ++ V ++NV PK + ++ DE ++
Sbjct: 135 CRTYHDVIPISCLTEFPNVVQMAKL---VCEDVNVDRFYPVLY-PKASRLIVTFDEHVIS 190
Query: 609 YQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDST 668
K G++Y K GQ++EEE+++ PAF EFL+ LG++V+L+ F+ +R LD T
Sbjct: 191 NNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQT 250
Query: 669 GTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNI 728
GT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV +VFQ+ PF P I
Sbjct: 251 GTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT-PFVPDMI 309
Query: 729 RSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKV 788
S+F H +V+V+ D Y V+VT DVP FGPP+P F K F++FLL K+
Sbjct: 310 ASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKL 369
Query: 789 INAENAAHKSEKFRAMATRTRQEYLKDLAEK 819
INAE A +K+EKF + RTR L+ L E+
Sbjct: 370 INAEYACYKAEKFAKLEERTRAALLETLYEE 400
>gi|224809578 RAP1 GTPase activating protein isoform a [Homo
sapiens]
Length = 727
Score = 222 bits (565), Expect = 3e-57
Identities = 128/331 (38%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 489 AYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLR 548
A YRK F KEH+NY+ D LG + S++ + G + R++ RT +
Sbjct: 151 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRT------K 198
Query: 549 GSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLN 608
D IP + + + ++ V ++NV PK + ++ DE ++
Sbjct: 199 CRTYHDVIPISCLTEFPNVVQMAKL---VCEDVNVDRFYPVLY-PKASRLIVTFDEHVIS 254
Query: 609 YQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDST 668
K G++Y K GQ++EEE+++ PAF EFL+ LG++V+L+ F+ +R LD T
Sbjct: 255 NNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQT 314
Query: 669 GTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNI 728
GT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV +VFQ+ PF P I
Sbjct: 315 GTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT-PFVPDMI 373
Query: 729 RSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKV 788
S+F H +V+V+ D Y V+VT DVP FGPP+P F K F++FLL K+
Sbjct: 374 ASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKL 433
Query: 789 INAENAAHKSEKFRAMATRTRQEYLKDLAEK 819
INAE A +K+EKF + RTR L+ L E+
Sbjct: 434 INAEYACYKAEKFAKLEERTRAALLETLYEE 464
>gi|224809573 RAP1 GTPase activating protein isoform b [Homo
sapiens]
Length = 681
Score = 222 bits (565), Expect = 3e-57
Identities = 128/331 (38%), Positives = 185/331 (55%), Gaps = 17/331 (5%)
Query: 489 AYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLR 548
A YRK F KEH+NY+ D LG + S++ + G + R++ RT +
Sbjct: 87 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRT------K 134
Query: 549 GSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLN 608
D IP + + + ++ V ++NV PK + ++ DE ++
Sbjct: 135 CRTYHDVIPISCLTEFPNVVQMAKL---VCEDVNVDRFYPVLY-PKASRLIVTFDEHVIS 190
Query: 609 YQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDST 668
K G++Y K GQ++EEE+++ PAF EFL+ LG++V+L+ F+ +R LD T
Sbjct: 191 NNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQT 250
Query: 669 GTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNI 728
GT S+Y +++ EIMFHVST LPYT + QQL RKRHIGNDIV +VFQ+ PF P I
Sbjct: 251 GTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT-PFVPDMI 309
Query: 729 RSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKV 788
S+F H +V+V+ D Y V+VT DVP FGPP+P F K F++FLL K+
Sbjct: 310 ASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKL 369
Query: 789 INAENAAHKSEKFRAMATRTRQEYLKDLAEK 819
INAE A +K+EKF + RTR L+ L E+
Sbjct: 370 INAEYACYKAEKFAKLEERTRAALLETLYEE 400
>gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo
sapiens]
Length = 1013
Score = 218 bits (556), Expect = 3e-56
Identities = 138/375 (36%), Positives = 206/375 (54%), Gaps = 30/375 (8%)
Query: 482 VEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRT 541
+E+ + +Y K+F + H NY G D P +S+ + + P I++R
Sbjct: 89 LENPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRV---PQYRAILWRK 145
Query: 542 SELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMK 601
+ + +P +S + L +K +L + + + R F+ P++ + L+
Sbjct: 146 TGTQKI-------CLP----YSPTKTLSVKSILSAMNLDKFEKGPREIFH-PEIQKDLLV 193
Query: 602 LDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQL 661
L+EQ + K G+++ K GQ T++EM++NE F++FL LLG+ + LKG+ YR L
Sbjct: 194 LEEQEGSVNFKFGVLFAKDGQLTDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGL 253
Query: 662 DTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQ--EPG 719
DTK D+TG HS+YT Y+ +EIMFHVSTMLPY+ NKQQ+ RKRHIGNDIVTIVFQ E
Sbjct: 254 DTKNDTTGIHSVYTVYQGHEIMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGEES 313
Query: 720 AQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNV 779
+ F P IRSHF H+F +VR +N +D+ Y + + VP FGPP+P F
Sbjct: 314 SPAFKPSMIRSHFTHIFALVR-YNQQNDN--YRLKIFSEESVPLFGPPLPTPPVFTDHQE 370
Query: 780 FRDFLLAKVINAENAAHKSEKFRAMATRT--------RQEYLKDLAEKNVTNTPIDPSGK 831
FRDFLL K+IN E A ++ F RT Q+ + DL KN+ N S
Sbjct: 371 FRDFLLVKLINGEKATLETPTFAQKRRRTLDMLIRSLHQDLMPDL-HKNMLNRR-SFSDV 428
Query: 832 FPFISLASKKKEKSK 846
P +++KKE+++
Sbjct: 429 LPESPKSARKKEEAR 443
>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
[Homo sapiens]
Length = 2083
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 594 KVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKG 653
K+ +L LD + K+ + Y GQ + + N A+E+F+ LG V L
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
Query: 654 FEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRK-RHIGNDIVT 712
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
Query: 713 IVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGV 772
IV+ E + + I + F V +++ P + + +S+ + + +VP FGP +
Sbjct: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVI---YPMKNHM-FSIQIMKKPEVPFFGPLFDGAI 1962
Query: 773 TFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPID 827
V + A INA A R YL+ + + ++ T +
Sbjct: 1963 V--NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
[Homo sapiens]
Length = 2036
Score = 73.2 bits (178), Expect = 2e-12
Identities = 60/235 (25%), Positives = 101/235 (42%), Gaps = 11/235 (4%)
Query: 594 KVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKG 653
K+ +L LD + K+ + Y GQ + + N A+E+F+ LG V L
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850
Query: 654 FEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRK-RHIGNDIVT 712
+ L K STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1907
Query: 713 IVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGV 772
IV+ E + + I + F V +++ P + + +S+ + + +VP FGP +
Sbjct: 1908 IVWSE-HTRDYRRGIIPTEFGDVLIVI---YPMKNHM-FSIQIMKKPEVPFFGPLFDGAI 1962
Query: 773 TFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPID 827
V + A INA A R YL+ + + ++ T +
Sbjct: 1963 V--NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQHHLEPTTFE 2015
>gi|118600961 akt substrate AS250 [Homo sapiens]
Length = 1873
Score = 71.2 bits (173), Expect = 8e-12
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 11/202 (5%)
Query: 594 KVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKG 653
K+ +L LD + K+ + Y GQ + + +NE A+E+F+ LG V L
Sbjct: 1630 KLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLST 1689
Query: 654 FEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRK-RHIGNDIVT 712
+ L + STG + Y E++FHVST +P ++ L +K RH+GND V
Sbjct: 1690 HCGFMGGLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP--SDSDDSLTKKLRHLGNDEVH 1746
Query: 713 IVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGV 772
IV+ E ++ + I + F V +I+ P + + + +A+T+ +VP FGP +
Sbjct: 1747 IVWSE-HSRDYRRGIIPTAFGDVSIII---YPMKNHM-FFIAITKKPEVPFFGPLFDGAI 1801
Query: 773 TFPKSNVFRDFLLAKVINAENA 794
K + + A INA A
Sbjct: 1802 VSGK--LLPSLVCATCINASRA 1821
>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
Length = 1740
Score = 64.7 bits (156), Expect = 8e-10
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 7/154 (4%)
Query: 591 NTPKVTEQLMKLDEQGLNYQ-QKVGIMYCKAGQSTEE-EMYNNESAGPAFEEFLQLLGER 648
N + E+ ++L +Q +Y K+ ++Y GQS E + +NE + EFL LG
Sbjct: 1455 NESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRL 1514
Query: 649 VRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIM---FHVSTMLPYTPNNKQQLLRKRH 705
+ LK + + L D G +T +IM FH++T++P +K + +KRH
Sbjct: 1515 IELKDCQPDKVYLGG-LDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRH 1573
Query: 706 IGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIV 739
+GND V+IV+ + G + F I+ F V VIV
Sbjct: 1574 LGNDFVSIVYNDSG-EDFKLGTIKGQFNFVHVIV 1606
>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
Length = 1807
Score = 64.7 bits (156), Expect = 8e-10
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 7/154 (4%)
Query: 591 NTPKVTEQLMKLDEQGLNYQ-QKVGIMYCKAGQSTEE-EMYNNESAGPAFEEFLQLLGER 648
N + E+ ++L +Q +Y K+ ++Y GQS E + +NE + EFL LG
Sbjct: 1522 NESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRL 1581
Query: 649 VRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIM---FHVSTMLPYTPNNKQQLLRKRH 705
+ LK + + L D G +T +IM FH++T++P +K + +KRH
Sbjct: 1582 IELKDCQPDKVYLGG-LDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRH 1640
Query: 706 IGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIV 739
+GND V+IV+ + G + F I+ F V VIV
Sbjct: 1641 LGNDFVSIVYNDSG-EDFKLGTIKGQFNFVHVIV 1673
>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
Length = 1784
Score = 64.7 bits (156), Expect = 8e-10
Identities = 48/154 (31%), Positives = 78/154 (50%), Gaps = 7/154 (4%)
Query: 591 NTPKVTEQLMKLDEQGLNYQ-QKVGIMYCKAGQSTEE-EMYNNESAGPAFEEFLQLLGER 648
N + E+ ++L +Q +Y K+ ++Y GQS E + +NE + EFL LG
Sbjct: 1499 NESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRL 1558
Query: 649 VRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIM---FHVSTMLPYTPNNKQQLLRKRH 705
+ LK + + L D G +T +IM FH++T++P +K + +KRH
Sbjct: 1559 IELKDCQPDKVYLGG-LDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRH 1617
Query: 706 IGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIV 739
+GND V+IV+ + G + F I+ F V VIV
Sbjct: 1618 LGNDFVSIVYNDSG-EDFKLGTIKGQFNFVHVIV 1650
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 62.8 bits (151), Expect = 3e-09
Identities = 164/760 (21%), Positives = 277/760 (36%), Gaps = 134/760 (17%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIP--RSISSDGRP--LERRLSPGSD 1131
P S P + TS + G D + P + P S +S P + LSPGS
Sbjct: 2567 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS- 2625
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + +SP + S++ +G V + R S G + SPAS
Sbjct: 2626 --TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 2682
Query: 1186 DRQNTQSDIG------GSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 2683 TSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 2730
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGH--SDSHYSSHSSSNTLSSNASSA 1297
H PA S + SG + + H SP+ G S +H ++ + +S S
Sbjct: 2731 THFPASS--------TTSGH-SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2781
Query: 1298 HSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGK- 1356
++ G T L+ + +S S TT+ P+ ++ +G +++ RS PG
Sbjct: 2782 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGST 2839
Query: 1357 -EKVAP-------LWHSSSEVISMADRTLETESHGLDRKTESSLSLD----IHSKSQAGS 1404
V+P L S+ V S + + ET R T +S+ + HS+ +
Sbjct: 2840 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTV--FPRSTTTSVRGEEPTTFHSRPASTH 2897
Query: 1405 TPLTRENSTFS-------------------------INDAASHTSTMSSRHSASPVVFTS 1439
T L E+ST S D ++T S ++ +
Sbjct: 2898 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2957
Query: 1440 ARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTIN---- 1495
ARS+ + + PS+L+PS + +++ P + + +T+ Y + P+ T++
Sbjct: 2958 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY-TSPRSPDATLSPATT 3016
Query: 1496 -SVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPES 1554
S G + S T ST S +PT+ + + + + S T S
Sbjct: 3017 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASS 3076
Query: 1555 --QKSFKFHALSSPQSP---------------FPSTPT--SRRALHRTLSDESIYNS--- 1592
Q+S FH SSP STPT S +LH TL+ S ++
Sbjct: 3077 LGQQSTTFH--SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQ 3134
Query: 1593 QREHFFTSRASLLD--------QALPNDVLFSSTYPSLPKSLP---LRRPSYTLGMK--- 1638
+ F S S D A P +V S+TY S P S P S TLG
Sbjct: 3135 EESTTFQSWPSSSDTTPSPPGTTAAPVEV--STTYHSRPSSTPTTHFSASSTTLGRSEES 3192
Query: 1639 -SLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFF 1697
++H A+ ++L + + +P P+ + + + +F+
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFY 3252
Query: 1698 AASDENHRPLSAAS--NSDQLEDQALAQMKPYSSSKDSSP 1735
++ LS AS +S E+ + +P S+ + P
Sbjct: 3253 SSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 3292
Score = 62.8 bits (151), Expect = 3e-09
Identities = 165/774 (21%), Positives = 277/774 (35%), Gaps = 124/774 (16%)
Query: 1078 SPQVPSQVQSPMTSRLNAGKGDG----KMPPPERAANIPRSISSDG---RPLERRLSPGS 1130
SP+ P+ SP ++ + + P P S ++ G SPGS
Sbjct: 3612 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 3671
Query: 1131 -DIYVTVSSMALARSQCRNSPSNLSS-SSDTGSVGGTYRQKSMPEGFGVSRRSPASIDR- 1187
D + +S + S ++ S+ SS S+DT G+ S + SP S
Sbjct: 3672 TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT 3731
Query: 1188 ----QNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLP 1243
T S I + S S + + + G Q S + H + T P
Sbjct: 3732 LFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG-ESTAFQTHPASTHTTPSP 3790
Query: 1244 AVSKVLPAFRESPSGRLMRQDPVVHL--SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDE 1301
+ P + R P H S GHS+ HSS + + SSAHS
Sbjct: 3791 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 3850
Query: 1302 KWYDGDRTESELN----SYNYLQGTSADSGID-------------TTSYGPSHGSTASLG 1344
G+ T S ++ L G++ G+ TT+ P+ ++ +G
Sbjct: 3851 SGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 3909
Query: 1345 AATSSPRSGPGK--EKVAP-------LWHSSSEVISMADRTLETESHGLDRKTESSLSLD 1395
+++ RS PG V+P L S+ V S + + ET R T +S+ +
Sbjct: 3910 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV--FPRSTTTSVRRE 3967
Query: 1396 ----IHSKSQAGSTPLTRENSTFS-------------------------INDAASHTSTM 1426
HS+ + T L E+ST S D ++T
Sbjct: 3968 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 4027
Query: 1427 SSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIG 1486
S ++ + ARS+ + + PS+L+PS + +++ P + + +T+ Y
Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY-TS 4086
Query: 1487 WKKPEGTIN-----SVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDL 1541
+ P+ T++ S G + S T ST S +PT+ + +
Sbjct: 4087 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST 4146
Query: 1542 KKLIDLESPTPES--QKSFKFHALSSPQSP---------------FPSTPT--SRRALHR 1582
+ + S T S Q+S FH SSP STPT S +LH
Sbjct: 4147 EATLSPGSTTASSLGQQSTTFH--SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT 4204
Query: 1583 TLSDESIYNS---QREHFFTSRASLLD--------QALPNDVLFSSTYPSLPKSLP---L 1628
TL+ S ++ + F S S D A+P +V S+TY S P S P
Sbjct: 4205 TLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEV--STTYHSRPSSTPTTHF 4262
Query: 1629 RRPSYTLGMK----SLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVD 1684
S TLG ++H A+ ++L + + +P P+ + +
Sbjct: 4263 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 4322
Query: 1685 AAKAYEVQRASFFAASDENHRPLSAAS--NSDQLEDQALAQMKPYSSSKDSSPT 1736
+ +F+++ LS AS +S E+ + +P S + P+
Sbjct: 4323 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPS 4376
Score = 61.6 bits (148), Expect = 7e-09
Identities = 160/758 (21%), Positives = 270/758 (35%), Gaps = 130/758 (17%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSIS----SDGRPLERRLSPGSD 1131
P S P + TS + G D + P + P S S + LSPGS
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGS- 1068
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + ++P + S++ +G V + R S G + SPAS
Sbjct: 1069 --TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 1125
Query: 1186 DRQNTQSDIGG------SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 1126 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 1173
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGH--SDSHYSSHSSSNTLSSNASSA 1297
H PA S + SG + + H SP+ G S +H ++ + +S S
Sbjct: 1174 THFPASS--------TTSGH-SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 1224
Query: 1298 HSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGK- 1356
++ G T L+ + +S S TT+ P+ ++ +G +++ RS PG
Sbjct: 1225 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGST 1282
Query: 1357 -EKVAP-------LWHSSSEVISMADRTLETE--SHGLDRKTESSLSLDIHSKSQAGSTP 1406
V+P L S+ V S + + ET H HS+ + T
Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342
Query: 1407 LTRENSTFS-------------------------INDAASHTSTMSSRHSASPVVFTSAR 1441
L E+ST S D ++T S ++ + AR
Sbjct: 1343 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 1402
Query: 1442 SSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTIN-----S 1496
S+ + + PS+L+PS + +++ P + + +T+ Y + P+ T++ S
Sbjct: 1403 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY-TSPRSPDATLSPATTTS 1461
Query: 1497 VGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPES-- 1554
G + S T ST S +PT+ + + + + S T S
Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLG 1521
Query: 1555 QKSFKFHALSSPQSP---------------FPSTPT--SRRALHRTLSDESIYNS---QR 1594
Q+S FH SSP STPT S +LH TL+ S ++ +
Sbjct: 1522 QQSTTFH--SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1579
Query: 1595 EHFFTSRASLLD--------QALPNDVLFSSTYPSLPKSLP---LRRPSYTLGMK----S 1639
F S S D A P +V S+TY S P S P S TLG +
Sbjct: 1580 STTFQSWPSSSDTTPSPPGTTAAPVEV--STTYHSRPSSTPTTHFSASSTTLGRSEESTT 1637
Query: 1640 LHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAA 1699
+H A+ ++L + + +P P+ + + + +F+++
Sbjct: 1638 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1697
Query: 1700 SDENHRPLSAAS--NSDQLEDQALAQMKPYSSSKDSSP 1735
LS AS +S E+ + +P S+ + P
Sbjct: 1698 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 1735
Score = 54.3 bits (129), Expect = 1e-06
Identities = 131/579 (22%), Positives = 208/579 (35%), Gaps = 114/579 (19%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G + LSPGS T SS+ +
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQESTA--SHSSPGST-DTTLSPGS---TTASSLGPESTTFH 1779
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+SP + ++ D + G + S + S T+ G + SW
Sbjct: 1780 SSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ---GESTTFQSWP 1836
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFV-----LEQHEYTEPTCHLPAVSKVLPAFRES----- 1255
S+D++ P ++FV + PT H A S L ES
Sbjct: 1837 SSKDTMPAP-------PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 1889
Query: 1256 -PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL---SSNASSAHSDEKWYDGDRTES 1311
P P + S +++SS S+ T+ S+ +S S+E RT
Sbjct: 1890 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES-----RTSH 1944
Query: 1312 ELNSYNYLQGTSADSGI--DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEV 1369
++ S S + + TSY S GSTA+ SS SG +E A HSS +
Sbjct: 1945 SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS--HSSQDA 2002
Query: 1370 -------------ISMADRTLETESHGLDRKTE----------SSLSLDIHSKSQAGSTP 1406
+ + + T S G T S S HS ++ +T
Sbjct: 2003 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATT 2062
Query: 1407 L----------TRENSTFSINDAASHTSTMS--------SRHSASPVVFTSARSSP---K 1445
L + E++T ++HT+ SRHS T++ SSP
Sbjct: 2063 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTD 2116
Query: 1446 EELHPAAPSQLAPSFSSSSS-SSSGPRSFYPRQGATSKYLIG-----WKKPEGTINSVGF 1499
L PA+ + PS S++S SS G G+T+ G + G+ ++ F
Sbjct: 2117 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 2176
Query: 1500 MDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQK-SF 1558
D+ S G A TR+ +ST R + P S + SP + + +F
Sbjct: 2177 PDST---TSSGIVEASTRVHSSTGSPRTTLSPASST-------------SPGLQGESTAF 2220
Query: 1559 KFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHF 1597
+ H S+ +P P + + T S ++ HF
Sbjct: 2221 QTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2259
Score = 52.8 bits (125), Expect = 3e-06
Identities = 129/569 (22%), Positives = 209/569 (36%), Gaps = 122/569 (21%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G P + LSPGS T SS+ +
Sbjct: 671 PGSTHTTAFPGSTTMPGLSQESTA--SHSSPG-PTDTTLSPGS---TTASSLGPEYTTFH 724
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+ P + ++ D + G + SMP S RSP + + G + SW
Sbjct: 725 SRPGSTETTLLPDNTTASGLL-EASMP--VHSSTRSPHTTLSPAGSTTRQGESTTFHSWP 781
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFVLEQHEYTE------PTCHLPAVSKVLPAFRESPSGR 1259
S+D+ P S +E + PT H+ A R + SG
Sbjct: 782 SSKDTRP--------APPTTTSAFVEPSTTSHGSPSSIPTTHISA--------RSTTSG- 824
Query: 1260 LMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYL 1319
L+ + H SP H+ +++ ++++HS S ++ +
Sbjct: 825 LVEESTTYHSSPGST--QTMHFPESDTTSGRGEESTTSHS-----------STTHTISSA 871
Query: 1320 QGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEV---------- 1369
T++ + TSY S GSTA+ SS SG +E A HSS +
Sbjct: 872 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS--HSSQDATGTIVLPARS 929
Query: 1370 ---ISMADRTLETESHGLDRKTE----------SSLSLDIHSKSQAGSTPL--------- 1407
+ + + T S G T S S HS ++ +T L
Sbjct: 930 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSG 989
Query: 1408 -TRENSTFSINDAASHTSTMS--------SRHSASPVVFTSARSSP---KEELHPAAPSQ 1455
+ E++T ++HT+ SRHS T++ SSP L PA+ +
Sbjct: 990 VSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTT 1043
Query: 1456 LAPSFSSSSS-SSSGPRSFYPRQGATSKYLIG-----WKKPEGTINSVGFMDTRKRHQSD 1509
PS S++S SSSG G+T+ G + G+ ++ F D+ S
Sbjct: 1044 SGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDST---TSS 1100
Query: 1510 GNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQK-SFKFHALSSPQS 1568
G A TR+ +ST R + P S + SP + + +F+ H S+ +
Sbjct: 1101 GIVEASTRVHSSTGSPRTTLSPASST-------------SPGLQGESTAFQTHPASTHTT 1147
Query: 1569 PFPSTPTSRRALHRTLSDESIYNSQREHF 1597
P P + + T S ++ HF
Sbjct: 1148 PSPPSTATAPVEESTTYHRSPGSTPTTHF 1176
Score = 52.4 bits (124), Expect = 4e-06
Identities = 124/551 (22%), Positives = 191/551 (34%), Gaps = 74/551 (13%)
Query: 1082 PSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMAL 1141
PS +S + + P + + P S ++ GR E S S + T+SS
Sbjct: 4538 PSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTH-TISSAPS 4596
Query: 1142 ARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQN-----------T 1190
S P++ SS GS T+ S G S S AS Q+ T
Sbjct: 4597 TTSALVEEPTSYHSSP--GSTATTHFPDSSTTS-GRSEESTASHSSQDATGTIVLPARST 4653
Query: 1191 QSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLP 1250
S + G ++P S ++ A + + G + S + PT H A S L
Sbjct: 4654 TSVLLGESTTSPISSGSMETTALPGSTTTPGLSE-KSTTFHSSPSSTPTTHFSASSTTLG 4712
Query: 1251 AFRES------PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL---SSNASSAHSDE 1301
ES P P + S +++SS S+ T+ S+ +S S+E
Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 4772
Query: 1302 KWYDGDRTESELNSYNYLQGTSADSGI--DTTSYGPSHGSTASLGAATSSPRSGPGKEKV 1359
RT ++ S S + + TSY S GS A+ SS SG +E
Sbjct: 4773 S-----RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEEST 4827
Query: 1360 APLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDA 1419
A HSS + + + G R ES+ T S S+
Sbjct: 4828 AS--HSSPDTNGITPLPAHFTTSG--RIAEST----------------TFYISPGSMETT 4867
Query: 1420 ASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGA 1479
+ T+T + S ++++S+RS P + L PA+ +SSS S P S Y + +
Sbjct: 4868 LASTATTPGLSAKSTILYSSSRS-PDQTLSPAS--------MTSSSISGEPTSLYSQAES 4918
Query: 1480 TSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEE 1539
T P T S ++ H G+ T S + S +T
Sbjct: 4919 THTTAF----PASTTTSGLSQESTTFHSKPGS----TETTLSPGSITTSSFAQEFTTPHS 4970
Query: 1540 DLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFT 1599
+ SP S LS + F S+P S + S+ +SQ+ F
Sbjct: 4971 QPGSALSTVSPA-----STTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFP 5025
Query: 1600 SRASLLDQALP 1610
LP
Sbjct: 5026 DSPGFTHTVLP 5036
Score = 51.6 bits (122), Expect = 7e-06
Identities = 131/562 (23%), Positives = 204/562 (36%), Gaps = 78/562 (13%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G + LSPGS T SS+ +
Sbjct: 3283 PGSTHTTAFPGSTTMPGVSQESTA--SHSSPGST-DTTLSPGS---TTASSLGPESTTFH 3336
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+ P + ++ D + G + S + S T+ G + SW
Sbjct: 3337 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ---GESTTFQSWP 3393
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFV-----LEQHEYTEPTCHLPAVSKVLPAFRES----- 1255
S+D+ P ++FV + PT H A S L ES
Sbjct: 3394 NSKDTTPAP-------PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 3446
Query: 1256 -PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL---SSNASSAHSDEKWYDGDRTES 1311
P P + S +++SS S+ T+ S+ +S +E T
Sbjct: 3447 SPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTH 3506
Query: 1312 ELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVIS 1371
++S T++ + TSY S GSTA+ SS SG +E A HSS +
Sbjct: 3507 TISS---APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS--HSSQDA-- 3559
Query: 1372 MADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHS 1431
T + L ++ +S+ L ++ ++P+ S+ S+ A ST + S
Sbjct: 3560 -------TGTIVLPARSTTSVLL-----GESTTSPI----SSGSMETTALPGSTTTPGLS 3603
Query: 1432 ASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPE 1491
F S+ SP L PA+ + S S++S S R G+T P+
Sbjct: 3604 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHS--------RPGSTHTTAF----PD 3651
Query: 1492 GTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPT 1551
T + H S G+ T L AST +S + T+ + + S T
Sbjct: 3652 STTTPGLSRHSTTSHSSPGSTDT-TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTT 3710
Query: 1552 PES--QKSFKFHALSSPQSP----FPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLL 1605
S Q+S FH SSP S FP + TS + + S S R S AS
Sbjct: 3711 ALSFGQESTTFH--SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL--SPASST 3766
Query: 1606 DQALPNDVLFSSTYPSLPKSLP 1627
L + T+P+ + P
Sbjct: 3767 SPGLQGESTAFQTHPASTHTTP 3788
Score = 51.2 bits (121), Expect = 9e-06
Identities = 100/436 (22%), Positives = 164/436 (37%), Gaps = 61/436 (13%)
Query: 1126 LSPGSDIYVTVSSMALARSQCRNSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPA 1183
LSPGS T SS+ + +SP + ++ D + G + S +
Sbjct: 4401 LSPGS---TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 4457
Query: 1184 SIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFV-----LEQHEYTEP 1238
S T+ G + SW S+D+ P ++FV + P
Sbjct: 4458 SPAGSTTRQ---GESTTFQSWPNSKDTTPAP-------PTTTSAFVELSTTSHGSPSSTP 4507
Query: 1239 TCHLPAVSKVLPAFRES------PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL-- 1290
T H A S L ES P P + S +++SS S+ T+
Sbjct: 4508 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHF 4567
Query: 1291 -SSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSS 1349
SN +S +E T ++S T++ + TSY S GSTA+ SS
Sbjct: 4568 PESNTTSGRGEESTTSHSSTTHTISS---APSTTSALVEEPTSYHSSPGSTATTHFPDSS 4624
Query: 1350 PRSGPGKEKVAPLWHSSSEVI-SMADRTLETESHGLDRKTESSLSL-DIHSKSQAGSTP- 1406
SG +E A HSS + ++ T S L T S +S + + + GST
Sbjct: 4625 TTSGRSEESTAS--HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 4682
Query: 1407 --LTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQL-APSFSSS 1463
L+ +++TF +S +ST ++ SAS + S P A + +P+ S++
Sbjct: 4683 PGLSEKSTTFH----SSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4738
Query: 1464 SSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTR 1523
S +++ G+T PE + S ++R H S + I
Sbjct: 4739 SGLVEESTAYHSSPGSTQTMHF----PESSTASGRSEESRTSHSSTTHTI---------- 4784
Query: 1524 DLRASPKPTSKSTIEE 1539
+SP T+ + +EE
Sbjct: 4785 ---SSPPSTTSALVEE 4797
Score = 49.7 bits (117), Expect = 3e-05
Identities = 99/474 (20%), Positives = 179/474 (37%), Gaps = 82/474 (17%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIP--RSISSDGRP--LERRLSPGSD 1131
P S P + TS + G D + P + P S +S P + LSPGS
Sbjct: 2093 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS- 2151
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + +SP + S++ +G V + R S G + SPAS
Sbjct: 2152 --TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 2208
Query: 1186 DRQNTQSDIGG------SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 2209 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 2256
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGH--SDSHYSSHSSSNTLSSNASSA 1297
H PA S + SG + + H SP+ G S +H ++ + +S S
Sbjct: 2257 THFPASS--------TTSGH-SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2307
Query: 1298 HSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGK- 1356
++ G T L+ + +S S TT+ P+ ++ +G +++ RS PG
Sbjct: 2308 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGST 2365
Query: 1357 ---------------EKVAPLWHSS--SEVISMADRTLETESHGLDRKTESSLSLDIHSK 1399
E+ ++ SS S ++ RT T G + T S H+
Sbjct: 2366 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTT 2425
Query: 1400 ---SQAGSTPLTRENSTFSINDAASHT---------------STMSSRHSASPVVFTSAR 1441
+ ++ LT E++ F + A++ T +T S ++ + AR
Sbjct: 2426 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPAR 2485
Query: 1442 SSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTIN 1495
S+ + + PS+L+PS + +++ P + + +T+ Y + P+ T++
Sbjct: 2486 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY-TSPRSPDATLS 2538
Score = 48.9 bits (115), Expect = 4e-05
Identities = 110/456 (24%), Positives = 163/456 (35%), Gaps = 71/456 (15%)
Query: 1082 PSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMAL 1141
PS +S + + P + + P S ++ GR E R S S + T+SS
Sbjct: 1898 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH-TISSPPS 1956
Query: 1142 ARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKST 1201
S P++ SS GS T+ S G S S AS Q+ I +ST
Sbjct: 1957 TTSALVEEPTSYHSS--PGSTATTHFPDSSTTS-GRSEESTASHSSQDATGTIVLPARST 2013
Query: 1202 PSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLM 1261
S VL T P + LP +P L
Sbjct: 2014 TS-------------------------VLLGESTTSPISSGSMETTALPGSTTTPG--LS 2046
Query: 1262 RQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQG 1321
+ H SP + S S+ SS +S ++++HS G + G
Sbjct: 2047 EKSTTFHSSPRSPATTLSPASTTSSG--VSEESTTSHS----RPGSTHTTAFPDSTTTPG 2100
Query: 1322 TSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETES 1381
S S TTS+ S GST + S+ SGP +E S +++ + S
Sbjct: 2101 LSRHS---TTSHS-SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS 2156
Query: 1382 HGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFS-INDAAS--HTSTMSSRHSASPVVFT 1438
G + T HS + T L +++T S I +A++ H+ST S R + SP T
Sbjct: 2157 FGQESTT-------FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2209
Query: 1439 S---ARSSPKEELHPA-----------APSQLAPSFSSSSSSSSGPRSFYPRQGATS--- 1481
S S + HPA A + + S + S S P + +P TS
Sbjct: 2210 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 2269
Query: 1482 -KYLIGWKKPE--GTINSVGFMDTRKRHQSDGNEIA 1514
K I P+ GT S T R +S + I+
Sbjct: 2270 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 2305
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/368 (20%), Positives = 130/368 (35%), Gaps = 54/368 (14%)
Query: 1270 SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSAD 1325
S GHS+ SHS + +HS + G+ S + S + L G++
Sbjct: 214 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 273
Query: 1326 SGI---DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTL----- 1377
+G+ TT Y +L A ++ K + + I+ D T
Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 333
Query: 1378 --ETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENST--FSINDAASHTSTMSSRHSAS 1433
T SH + T+++LS + S G T +S +T+T +++
Sbjct: 334 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393
Query: 1434 PVVFTSARSSPKEELHPAAPS---------QLAPSFSSSSSSSSGPRSFYPRQGATSKYL 1484
PV S+ SP L P++ + Q PS +S + SG S + + T
Sbjct: 394 PV--HSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYH-- 449
Query: 1485 IGWKKPEGT-INSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKST---IEE- 1539
P T T H + + + + +T +P P +T +EE
Sbjct: 450 ---SSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT-----TPPPARSATSGHVEES 501
Query: 1540 ----------DLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESI 1589
+ + + S++S FH S STP++ AL T S+
Sbjct: 502 TAYHRSPGSTQTMHFPESSTTSGHSEESATFH--GSTTHTKSSTPSTTAALAHTSYHSSL 559
Query: 1590 YNSQREHF 1597
+++ HF
Sbjct: 560 GSTETTHF 567
Score = 43.9 bits (102), Expect = 0.001
Identities = 110/540 (20%), Positives = 207/540 (38%), Gaps = 56/540 (10%)
Query: 1078 SPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRL---SPGSDIYV 1134
+P PS +P+ + G P + P S ++ G + + SP +
Sbjct: 2230 TPSPPSTATAPVEESTTYHRSPGSTP----TTHFPASSTTSGHSEKSTIFHSSPDASGTT 2285
Query: 1135 TVSSMALARSQCRNSPSNLS-SSSDTGSVGGTYRQKSMPEG---FGVSRRSPASIDRQNT 1190
S+ + + ++ S +S S++ ++ G+ + E F S RSP + +
Sbjct: 2286 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 2345
Query: 1191 QSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLP 1250
+ +G +ST S RS+ +S P + L + E T P ++
Sbjct: 2346 MTSLGVGEESTTS--RSQPG----STHSTVSPASTTTPGLSE-ESTTVYSSSPGSTETT- 2397
Query: 1251 AFRESPSGRLMRQDPVV-HLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRT 1309
F +P+ + ++P H P S+H++ T S S + + G
Sbjct: 2398 VFPRTPTTSVRGEEPTTFHSRPA---------STHTTLFTEDSTTSGLTEESTAFPGSPA 2448
Query: 1310 ESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSG-PGKEKVAPLWHSSSE 1368
++ L T+AD G ++T++ S GST + + S SG G+ + L SS+E
Sbjct: 2449 STQTGLPATL--TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2506
Query: 1369 VISMADRTLETESHGLDRKTESSLSLDIHSKS-QAGSTPLTRENSTFSINDAASHTSTMS 1427
++ S +E S + +S A +P T +S S + SH+ S
Sbjct: 2507 TTTLPG------SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGS 2560
Query: 1428 SRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGP----RSFYPRQGATSKY 1483
+ +A P T+ S ++P + +S+++SGP + + G+T
Sbjct: 2561 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTA 2620
Query: 1484 LIGWKKPEGTINSVGF-MDTRKRHQSDGNEIAHTRL----RASTRDLRASPKPTSKSTIE 1538
L G+ ++ F ++ H S G+ HT L S+ + AS + S +
Sbjct: 2621 L-----SPGSTTALSFGQESTTFHSSPGS--THTTLFPDSTTSSGIVEASTRVHSSTGSP 2673
Query: 1539 EDLKKLIDLESPTPESQK-SFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHF 1597
SP + + +F+ H S+ +P P + + T S ++ HF
Sbjct: 2674 RTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2733
Score = 41.6 bits (96), Expect = 0.007
Identities = 143/704 (20%), Positives = 237/704 (33%), Gaps = 123/704 (17%)
Query: 1112 PRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSS---SDTGSVGGTYRQ 1168
P + S E LSPGS T SS+ + +SP + ++ DT + G +
Sbjct: 4136 PTTSHSSQGSTEATLSPGS---TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV--E 4190
Query: 1169 KSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSF 1228
S P +T + + + SW S D+ + + + ++
Sbjct: 4191 ASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTY 4250
Query: 1229 VLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSN 1288
+ PT H A S L ES + VH SP G + + + S+++
Sbjct: 4251 --HSRPSSTPTTHFSASSTTLGRSEESTT---------VHSSPGATG--TALFPTRSATS 4297
Query: 1289 TL-----SSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASL 1343
L +S SS ++ G T + L+ + +S S T S + S S
Sbjct: 4298 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE 4357
Query: 1344 GAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAG 1403
+ TS R G P SS+ + ++ + T SH T+++LS + S G
Sbjct: 4358 ESTTSHSRPGSMHTTAFP---SSTTMPGVSQES--TASHSSPGSTDTTLSPGSTTASSLG 4412
Query: 1404 STPLTRENSTFSINDAASHTSTMSSRHSASPVVFTS-----ARSSPKEELHPA------- 1451
E++TF + ++ T+ + +AS ++ S + SP L PA
Sbjct: 4413 P-----ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 4467
Query: 1452 ----------------APSQLAPSFSSSSSSSSG-PRSFYPRQGATSKYLIGWKKPEGTI 1494
AP +F S++S G P S + S +G + T+
Sbjct: 4468 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 4527
Query: 1495 NSVGFM-----------------DTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTI 1537
+S ++ H S G+ ++T R TS S+
Sbjct: 4528 HSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587
Query: 1538 EEDLKKLIDLESPTPESQKSFKFHALSSPQSPFP-STPTSRRALHRTLSDE--------- 1587
+ S E S+ S+ + FP S+ TS R+ T S
Sbjct: 4588 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 4647
Query: 1588 -------SIYNSQREHFFTSRASLLDQALPNDVLF------SSTYPSLPKSLPLRRPSYT 1634
S+ + S S+ ALP S+T+ S P S P
Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT----- 4702
Query: 1635 LGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRA 1694
FSAS ++L +E+ P A S LV+ + AY
Sbjct: 4703 --------HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT-SGLVEESTAYHSSPG 4753
Query: 1695 SFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSSPTLA 1738
S + H P S+ ++ E + ++ S S T A
Sbjct: 4754 S----TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSA 4793
Score = 41.2 bits (95), Expect = 0.009
Identities = 85/391 (21%), Positives = 143/391 (36%), Gaps = 56/391 (14%)
Query: 1082 PSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMAL 1141
P +S + + + P + + P S ++ G E GS + S+ +
Sbjct: 487 PPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPST 546
Query: 1142 ARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKST 1201
+ S + S++T +R S G S S AS + + ST
Sbjct: 547 TAALAHTSYHSSLGSTETTH----FRDSSTISGR--SEESKASHSSPDAMATTVLPAGST 600
Query: 1202 PSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLM 1261
PS + + P +S +E T P +S+ F SP
Sbjct: 601 PSVLVGDST-----------PSPISSGSMETTALPGSTTK-PGLSEKSTTFYSSP----- 643
Query: 1262 RQDPVVHL--SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYL 1319
R HL S G S+ +SHS + + A + G T L+ +
Sbjct: 644 RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA---------FPGSTTMPGLSQESTA 694
Query: 1320 QGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLET 1379
+S G T+ P + +SLG ++ S PG S+E + D T T
Sbjct: 695 SHSSP--GPTDTTLSPGSTTASSLGPEYTTFHSRPG----------STETTLLPDNT--T 740
Query: 1380 ESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHS-ASPVVFT 1438
S L+ S+ +HS +++ T L+ ST ++ + S SS+ + +P T
Sbjct: 741 ASGLLEA------SMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTT 794
Query: 1439 SARSSPKEELHPAAPSQLAPSFSSSSSSSSG 1469
SA P H +PS + + S+ S++SG
Sbjct: 795 SAFVEPSTTSH-GSPSSIPTTHISARSTTSG 824
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 62.0 bits (149), Expect = 5e-09
Identities = 136/684 (19%), Positives = 242/684 (35%), Gaps = 11/684 (1%)
Query: 1071 NASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGS 1130
++S S S +S + K D + + + +S SSD + S S
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS--SDNS 654
Query: 1131 DIYVTVSSMALARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNT 1190
D + +S + S + S+ SSSSD+ + + S S +S +
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 1191 QSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLP 1250
SD S S S DS + D ++ + S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 1251 AFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTE 1310
+S + S + SDS SS SS ++ SS++ S++S + D ++
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 1311 SELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVI 1370
S NS + + + G D+ S S S +S ++ SS S + + SS
Sbjct: 835 SS-NSSDSSDSSDSSDGSDSDSSNRSDSSNSS-DSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 1371 SMADRTLETESHGLDRKTESSLSLDIHSK-SQAGSTPLTRENSTFSINDAASHTSTMSSR 1429
+D + ++S D S S +S S S NS+ S N + S S+ SS
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 1430 HSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKK 1489
S S S+ SS + + + S + S SS SS S S +S
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 1490 PEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLES 1549
+ + +S + + SD ++ + + + + D S +S S+ D D
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSSDSSDSSDSSD 1071
Query: 1550 PTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRAS----LL 1605
+ S S + S S S+ +S + SD S + + +S +S
Sbjct: 1072 SSDSSDSSDSSESSDSSDSS-NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 1606 DQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDP 1665
D + +D SS +S S + +SDSS +
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 1666 GLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMK 1725
D++ D S+ D++ + + +S + S ++ ++ +SD + +
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Query: 1726 PYSSSKDSSPTLASKVDQLEGMLK 1749
S S DSS + + D+ + K
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 58.2 bits (139), Expect = 7e-08
Identities = 117/641 (18%), Positives = 231/641 (36%), Gaps = 48/641 (7%)
Query: 1094 NAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNL 1153
++GKG + + + S SSD S SD + SS S +S S+
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSD--------SSDSDSSDSNSSSDSDSSDSDSSDSSD 592
Query: 1154 SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIAD 1213
S SSD+ + + + S S + D ++SD S + S + +D
Sbjct: 593 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 1214 QMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNK 1273
S +S + + ++ + S N
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSD--------------------------SSNS 686
Query: 1274 QGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSY 1333
SDS SS+SS ++ SS++S + S + + S+ +S N + + + D++
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 1334 GPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLS 1393
S S+ S ++ SS S + SS D + ++S ++SS S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 1394 LDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAP 1453
D S + + + + + + +D++ +++ S S+ + + SS + + ++
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 1454 SQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEI 1513
S + S+SS SS S + S + + +S + + SD +E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 1514 AHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPST 1573
+++ +++ D S S S+ D D + + S S + SS S ++
Sbjct: 927 SNSSDNSNSSDSSNS----SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 1574 PTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSY 1633
S SD S + + +S +S D + +D SS S S
Sbjct: 983 SDS--------SDSSDSSDSSDSSDSSNSS--DSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 1634 TLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQR 1693
+ +SDSS + D++ D S+ +++ + +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 1694 ASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSS 1734
+S + S ++ ++ +SD + + S S DSS
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Score = 45.1 bits (105), Expect = 6e-04
Identities = 90/470 (19%), Positives = 179/470 (38%), Gaps = 19/470 (4%)
Query: 1272 NKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTT 1331
+ +G D S S +N SN + + ++ D D+++S + S+DS +
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGND---DNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 1332 SYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESS 1391
S S ++ +++ S S + SS+ + +D + ++S ++SS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSD--SDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 1392 LSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPA 1451
S SKS++ S+ ++ + N + S ++ SS S S S+ SS + +
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 1452 APSQLAP--SFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSD 1509
+ S + S SS SS+SS + S ++ D+ + SD
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS-------SDSSDSSNSNSSDSDSSNSSD 733
Query: 1510 GNEIAHTRLRASTRDLRAS--PKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQ 1567
++ +++ + + D S +S S+ D D + S S + +S
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793
Query: 1568 S--PFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKS 1625
S S+ +S + SD S +S ++ + D + +D SS S
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853
Query: 1626 LPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAAD-LDWSNLVD 1684
R + S S++ S +D ++ + +D D SN D
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 1685 AAKAYEVQRASFFAASDENHRPLSAASNSDQLEDQALAQMKPYSSSKDSS 1734
++ + +S + S +N ++++SD + + S+S DSS
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Score = 45.1 bits (105), Expect = 6e-04
Identities = 82/371 (22%), Positives = 133/371 (35%), Gaps = 23/371 (6%)
Query: 92 ESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDS 151
++S SS +S+ DS S S S SS S NS+DS S + N + S++ DS
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS----SDSSDSSNSSESSDSSDS 707
Query: 152 RFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSS 211
S ++SD + S DS D S S+ S
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767
Query: 212 IDKQGTSGESFFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQREN 271
D +S S D + S + S+ + S S D D S +
Sbjct: 768 SDSSDSSDSS--DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 272 LRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCF 331
+ S++ DSS ++ + SSD D S DS
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD--SSDS---------- 873
Query: 332 AHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTED 391
++ S D NE+ N + N++ S+ + S S S+S+ S S+++
Sbjct: 874 SNSSDSSDSSDSNES-SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 392 LNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESA----SF 447
NS S + D S+ S ++ + S S +S S + +S+ S
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 448 ESTLSSHCTNA 458
+S+ SS +N+
Sbjct: 993 DSSDSSDSSNS 1003
Score = 41.6 bits (96), Expect = 0.007
Identities = 80/370 (21%), Positives = 127/370 (34%), Gaps = 36/370 (9%)
Query: 89 NIKESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSEN 148
N ESS SS ++ S S SS S+ SS S +S+DS+ N + S++
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS----------NSSDSSDS 746
Query: 149 MDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGS 208
DS + S + +SD + S DS D S + S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 209 TSSIDKQGTSGESFFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQ 268
+ S D +S D S + SD + S S D DG S
Sbjct: 807 SDSSDSSDSS------------DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 269 RENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCP 328
N R S + DSS N+ S+ N S+ S +
Sbjct: 855 SSN------------RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 329 KCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGS 388
+ S D + + + + N+ + S+ + S S S+S+ S+ S
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962
Query: 389 TEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFE 448
+ +S S S D D ++ S + + + S S+ S S S S +
Sbjct: 963 SNSSDSSDSNSSDSSDSSNSS--DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 449 STLSSHCTNA 458
S+ SS +N+
Sbjct: 1021 SSNSSDSSNS 1030
Score = 41.2 bits (95), Expect = 0.009
Identities = 77/367 (20%), Positives = 131/367 (35%), Gaps = 26/367 (7%)
Query: 93 SSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDSR 152
SS SS ++S+ DS S S S SS S +SNDS+ S + N + S + DS
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSN-SSDSSDSSNSSDSSNSSDS- 809
Query: 153 FLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSSI 212
++ SS + ++SD + S DS D S S +R S SS
Sbjct: 810 ---SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 213 DKQGTSGESFFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENL 272
+ + D ++S + S+ + S S S
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 273 RLFKEREKPLKRRSKSETGDSS-IFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCF 331
+ + S++ DSS ++ + SSD D+ S DS
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS---------- 976
Query: 332 AHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTED 391
+ S D +++ + + ++ + S+ + S S S+S+ S+ S++
Sbjct: 977 SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 392 LNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTL 451
+S S D S+ + + S S+ S S S S ES+
Sbjct: 1037 SDSSDSSDSSDSSDSSD----------SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 452 SSHCTNA 458
SS +N+
Sbjct: 1087 SSDSSNS 1093
Score = 39.7 bits (91), Expect = 0.027
Identities = 96/497 (19%), Positives = 176/497 (35%), Gaps = 21/497 (4%)
Query: 1254 ESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESEL 1313
E P + + V H + +SD + S ++ + ++ + D +ES+
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483
Query: 1314 NS-----YNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPG--------KEKVA 1360
NS +Y S D+G + S G + S +S +G G K
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 1361 PLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAA 1420
SS+ S S D + S S S + S+ + +S+ S N +
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 1421 SHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGAT 1480
S S+ SS S S S S K E + S + S S SS S+S S +
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSDSSKSE----SDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 1481 SKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEED 1540
S + + +S + + SD ++ + + + + D S S + +
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 1541 LKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTS 1600
D +S + SS S ++ S + + S +S +S S
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 1601 RAS--LLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETR 1658
S D + +D SS S S + S + S++ S +D +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 1659 -RQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLE 1717
D D++ D SN D++ + + +S + S +++ +++ +SD
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS-S 898
Query: 1718 DQALAQMKPYSSSKDSS 1734
+ + + S+S DSS
Sbjct: 899 NSSDSDSSDSSNSSDSS 915
Score = 38.1 bits (87), Expect = 0.078
Identities = 84/370 (22%), Positives = 130/370 (35%), Gaps = 16/370 (4%)
Query: 92 ESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDS 151
+S S + SS DS S +S S SS S +S+DS+ ++ S + DS
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638
Query: 152 RFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSS 211
+ SS + +SD + S DS D S + S+ S
Sbjct: 639 K------SDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 212 IDKQGTSGES-FFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRE 270
D +S S D D SD + + SD + S S D D S
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS--SDSS 750
Query: 271 NLRLFKEREKPLKRRSKSETGDSSIFRKLRNAK-GEELGKSSDLED-NRSEDSVRPWTCP 328
N + S++ DSS N+ + SSD D + S DS
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 329 KCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGS 388
D S N + + + + ++ +S ++ +S S S + S SS
Sbjct: 811 DSSDSSDSDS----SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 389 TEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFE 448
+ D + + S SNE S + + + S S S+ S S S S E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS-SNSSDSSDSSNSSDSSE 925
Query: 449 STLSSHCTNA 458
S+ SS +N+
Sbjct: 926 SSNSSDNSNS 935
Score = 37.7 bits (86), Expect = 0.10
Identities = 80/376 (21%), Positives = 135/376 (35%), Gaps = 11/376 (2%)
Query: 89 NIKESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSEN 148
N ++S SS +S DS S +S S SS S NS+DS+ S ++ + + S++
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS--DSSNSSDS 985
Query: 149 MDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGS 208
DS + S + +SD + S +S D S S
Sbjct: 986 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDS 1045
Query: 209 TSSIDKQGTSGESFFDLLKGYKD--DKSDRGPT--PTKLSDFLITGGGKGSGFSLDVIDG 264
+ S D +S S D D SD + ++ SD + S S D D
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105
Query: 265 PISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAK-GEELGKSSDLEDNRSEDSVR 323
S + + S++ DSS N+ + +SSD D+
Sbjct: 1106 --SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 324 PWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFS 383
+ + S D +++ + + ++ + S+ + S S S S+ S
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Query: 384 SPMGSTEDLNSKGSLSMDQGDDKSNELVMS-CPYFRNEIGGEGERKISLSKSNSGSFSGC 442
S++ S S D SN S + + S SKS +G+ +G
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1283
Query: 443 ESAS-FESTLSSHCTN 457
+S S E + S+H T+
Sbjct: 1284 DSDSDSEGSDSNHSTS 1299
Score = 35.8 bits (81), Expect = 0.39
Identities = 79/367 (21%), Positives = 132/367 (35%), Gaps = 24/367 (6%)
Query: 92 ESSRSSQEIETSSCLDSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDS 151
+SS SS ++S+ DS S +S + SS S NS+DS S + N + S + DS
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS----SDSSDSSNSSDSSNSSDS 962
Query: 152 RFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSS 211
+ SS + ++SD + S DS D S S++S
Sbjct: 963 ----SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 212 IDKQGTSGESFFDLLKGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQREN 271
D +S S D SD + + SD + S S D D S +
Sbjct: 1019 SDSSNSSDSS-------NSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 272 LRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCF 331
+ SE+ DSS ++ + SSD D+ +
Sbjct: 1071 -----DSSDSSDSSDSSESSDSS--DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 332 AHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTED 391
+ S D +++ + + ++ + S+ + S S S S+ S S++
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 392 LNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTL 451
+S S D S+ S ++ + S S S+ S S S S +S+
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDSSDSNESSDSSDSSD 1242
Query: 452 SSHCTNA 458
SS +N+
Sbjct: 1243 SSDSSNS 1249
Score = 35.0 bits (79), Expect = 0.66
Identities = 78/354 (22%), Positives = 128/354 (36%), Gaps = 29/354 (8%)
Query: 107 DSLSSKSSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTRPSENMDSRFLMPEAYPSSPRKA 166
DS KS SS S NS+DS+ ++ N + S++ DS ++ SS +
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS-----DSSDSSDSDS 595
Query: 167 LRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLL 226
+SD + S DS D S + S E S+ S K +S + D
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKS----DSSKSESDSSDSDSKSDSSDSNSSD-- 649
Query: 227 KGYKDDKSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRS 286
D SD + SD + S S D + S + S
Sbjct: 650 SSDNSDSSD-SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 287 KSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEA 346
S++ DSS ++ + S + + S DS + S D +++
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS----------SDSSDSSNSSDSSDS 758
Query: 347 IMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSL-SMDQGD- 404
+ ++ ++ + S+ + S S S+S+ S S++ NS S S D D
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818
Query: 405 DKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNA 458
D SN S N S S +S S G +S S + SS+ +++
Sbjct: 819 DSSNSSDSS-----NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 61.6 bits (148), Expect = 7e-09
Identities = 160/758 (21%), Positives = 270/758 (35%), Gaps = 130/758 (17%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSIS----SDGRPLERRLSPGSD 1131
P S P + TS + G D + P + P S S + LSPGS
Sbjct: 497 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGS- 555
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + ++P + S++ +G V + R S G + SPAS
Sbjct: 556 --TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 612
Query: 1186 DRQNTQSDIGG------SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 613 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 660
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGH--SDSHYSSHSSSNTLSSNASSA 1297
H PA S + SG + + H SP+ G S +H ++ + +S S
Sbjct: 661 THFPASS--------TTSGH-SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 711
Query: 1298 HSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGK- 1356
++ G T L+ + +S S TT+ P+ ++ +G +++ RS PG
Sbjct: 712 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPASMTSLGVGEESTTSRSQPGST 769
Query: 1357 -EKVAP-------LWHSSSEVISMADRTLETE--SHGLDRKTESSLSLDIHSKSQAGSTP 1406
V+P L S+ V S + + ET H HS+ + T
Sbjct: 770 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 829
Query: 1407 LTRENSTFS-------------------------INDAASHTSTMSSRHSASPVVFTSAR 1441
L E+ST S D ++T S ++ + AR
Sbjct: 830 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 889
Query: 1442 SSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTIN-----S 1496
S+ + + PS+L+PS + +++ P + + +T+ Y + P+ T++ S
Sbjct: 890 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY-TSPRSPDATLSPATTTS 948
Query: 1497 VGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPES-- 1554
G + S T ST S +PT+ + + + + S T S
Sbjct: 949 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLG 1008
Query: 1555 QKSFKFHALSSPQSP---------------FPSTPT--SRRALHRTLSDESIYNS---QR 1594
Q+S FH SSP STPT S +LH TL+ S ++ +
Sbjct: 1009 QQSTTFH--SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1066
Query: 1595 EHFFTSRASLLD--------QALPNDVLFSSTYPSLPKSLP---LRRPSYTLGMK----S 1639
F S S D A P +V S+TY S P S P S TLG +
Sbjct: 1067 STTFQSWPSSSDTTPSPPGTTAAPVEV--STTYHSRPSSTPTTHFSASSTTLGRSEESTT 1124
Query: 1640 LHGEFSASDSSLTDIQETRRQPMPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAA 1699
+H A+ ++L + + +P P+ + + + +F+++
Sbjct: 1125 VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS 1184
Query: 1700 SDENHRPLSAAS--NSDQLEDQALAQMKPYSSSKDSSP 1735
LS AS +S E+ + +P S+ + P
Sbjct: 1185 PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 1222
Score = 57.0 bits (136), Expect = 2e-07
Identities = 134/563 (23%), Positives = 207/563 (36%), Gaps = 110/563 (19%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G P + LSPGS T SS+ +
Sbjct: 158 PGSTHTTAFPGSTTMPGLSQESTA--SHSSPG-PTDTTLSPGS---TTASSLGPEYTTFH 211
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+ P + ++ D + G + SMP S RSP + + G + SW
Sbjct: 212 SRPGSTETTLLPDNTTASGLL-EASMP--VHSSTRSPHTTLSPAGSTTRQGESTTFHSWP 268
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFVLEQHEYTE------PTCHLPAVSKVLPAFRESPSGR 1259
S+D+ P S +E + PT H+ A R + SG
Sbjct: 269 SSKDTRP--------APPTTTSAFVEPSTTSHGSPSSIPTTHISA--------RSTTSG- 311
Query: 1260 LMRQDPVVHLSPNK------------QGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGD 1307
L+ + H SP G + +SHSS+ S+A S S
Sbjct: 312 LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTS-------- 363
Query: 1308 RTESELNSYNYLQGTSADSGI--DTTSYGPSHGSTAS---------------------LG 1344
E SY+ G++A + +T+ G S STAS LG
Sbjct: 364 ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 423
Query: 1345 AATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGS 1404
+T+SP S E A +++ +S T + T S S S+ +
Sbjct: 424 ESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRS-PATTLSPASTTSSGVSEEST 482
Query: 1405 TPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEE---LHPAAPSQLAPSFS 1461
T +R ST + S T+ SRHS T++ SSP L PA+ + PS
Sbjct: 483 TSRSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTTSGPSQE 536
Query: 1462 SSSS-SSSGPRSFYPRQGATSKYLIG-----WKKPEGTINSVGFMDTRKRHQSDGNEIAH 1515
S++S SSSG G+T+ G + G+ ++ F D+ S G A
Sbjct: 537 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDST---TSSGIVEAS 593
Query: 1516 TRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQK-SFKFHALSSPQSPFPSTP 1574
TR+ +ST R + P S + SP + + +F+ H S+ +P P +
Sbjct: 594 TRVHSSTGSPRTTLSPASST-------------SPGLQGESTAFQTHPASTHTTPSPPST 640
Query: 1575 TSRRALHRTLSDESIYNSQREHF 1597
+ T S ++ HF
Sbjct: 641 ATAPVEESTTYHRSPGSTPTTHF 663
Score = 46.2 bits (108), Expect = 3e-04
Identities = 90/359 (25%), Positives = 133/359 (37%), Gaps = 62/359 (17%)
Query: 1275 GHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSADSGI-- 1328
G S+ +SHSS + +++ A S GD T S ++S + L G++ G+
Sbjct: 62 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 121
Query: 1329 -DTTSY-GPSHGSTASLGAA-----------TSSPRSG-------PGKEKVAPLWHSSSE 1368
TT Y P T L A+ TS R G PG + L S+
Sbjct: 122 KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 181
Query: 1369 VISMADRTLETESHGLDRKTESSLSLD---IHSKSQAGSTPLTRENSTFSINDAAS---H 1422
S T T S G T SSL + HS+ + T L +N+T S AS H
Sbjct: 182 SHSSPGPTDTTLSPG--STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 239
Query: 1423 TSTMSSRHSASPVVFTSARSS--------PKEELHPAAPSQ----LAPSFSSSSSSSSGP 1470
+ST S + SP T+ + ++ PA P+ + PS +S S SS P
Sbjct: 240 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 299
Query: 1471 RSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPK 1530
+ + TS G + ++ H S G+ + T R
Sbjct: 300 TTHISARSTTS----------GLVE-----ESTTYHSSPGSTQTMHFPESDTTSGRGEES 344
Query: 1531 PTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFP-STPTSRRALHRTLSDES 1588
TS S+ + S E S+ S+ + FP S+ TS R+ T S S
Sbjct: 345 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 403
Score = 43.5 bits (101), Expect = 0.002
Identities = 85/360 (23%), Positives = 139/360 (38%), Gaps = 63/360 (17%)
Query: 1292 SNASSAHSDEK-WYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSP 1350
S+ +S HS+E + G T ++ ++ S + + TSY S GST + SS
Sbjct: 6 SSTTSGHSEESATFHGSTTHTKSST------PSTTAALAHTSYHSSLGSTETTHFRDSST 59
Query: 1351 RSGPGKEKVAPLWHSSSEVIS-------------MADRTLETESHGLDRKTE-------- 1389
SG +E A HSS + ++ + D T S G T
Sbjct: 60 ISGRSEESKAS--HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKP 117
Query: 1390 --SSLSLDIHSKSQAGST---PLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSP 1444
S S +S ++ T P + +S S SH+ S+ +A P T S
Sbjct: 118 GLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQ 177
Query: 1445 KEELHPAAPSQLAPSFS--SSSSSSSGPR--SFYPRQGATSKYLIGWKKPEGTINSVGFM 1500
+ ++P + S S+++SS GP +F+ R G+T L+ P+ T S G +
Sbjct: 178 ESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLL----PDNTTAS-GLL 232
Query: 1501 D--------TRKRHQSDGNEIAHTRLRAST--------RDLRASPKPTSKSTIEEDLKKL 1544
+ TR H + + TR ST +D R +P T+ + +E
Sbjct: 233 EASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 292
Query: 1545 IDLES-PTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRAS 1603
S PT L + + S+P S + +H SD + + + E TS +S
Sbjct: 293 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT--SGRGEESTTSHSS 350
Score = 40.4 bits (93), Expect = 0.016
Identities = 119/577 (20%), Positives = 207/577 (35%), Gaps = 80/577 (13%)
Query: 1112 PRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSS---SDTGSVGGTYRQ 1168
P + S E LSPGS T SS+ + +SP + ++ DT + G +
Sbjct: 983 PTTSHSSQGSTEATLSPGS---TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV--E 1037
Query: 1169 KSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSF 1228
S P +T + + + SW S D+ + P + ++
Sbjct: 1038 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT-AAPVEVSTT 1096
Query: 1229 VLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSN 1288
+ T PT H A S L ES + VH SP G + + + S+++
Sbjct: 1097 YHSRPSST-PTTHFSASSTTLGRSEESTT---------VHSSPGATG--TALFPTRSATS 1144
Query: 1289 TL-----SSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASL 1343
L +S SS ++ G T + L+ + +S S T S + S S
Sbjct: 1145 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE 1204
Query: 1344 GAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAG 1403
+ TS R G P S+ + ++ + T SH T+++LS + S G
Sbjct: 1205 ESTTSHSRPGSTHTTAFP---GSTTMPGVSQES--TASHSSPGSTDTTLSPGSTTASSLG 1259
Query: 1404 STPLTRENSTFSINDAASHTSTMSSRHSASPVVFTS-----ARSSPKEELHPAAPSQLAP 1458
E++TF + ++ T+ + +AS ++ S + SP L PA
Sbjct: 1260 P-----ESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG------ 1308
Query: 1459 SFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRL 1518
S++ S +P T P + F++ + T
Sbjct: 1309 --STTRQGESTTFQSWPSSKDT--------MPAPPTTTSAFVELSTTSHGSPSSTPTTHF 1358
Query: 1519 RASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRR 1578
AS+ L S + T+ + + +P+P + L + + S+P S +
Sbjct: 1359 SASSTTLGRSEESTTVHS-----SPVATATTPSPARSTT---SGLVEESTAYHSSPGSTQ 1410
Query: 1579 ALHRTLSDESIYNSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMK 1638
+H + S + + E TS +S S+ PS +L SY
Sbjct: 1411 TMH--FPESSTASGRSEESRTSHSSTTHTI--------SSPPSTTSALVEEPTSYHSSPG 1460
Query: 1639 SL---HGEFSASDSSLTDIQETRRQPMPDP-GLMPLP 1671
S+ H S++ S ++ + T PD G+ PLP
Sbjct: 1461 SIATTHFPESSTTSGRSE-ESTASHSSPDTNGITPLP 1496
Score = 39.7 bits (91), Expect = 0.027
Identities = 57/230 (24%), Positives = 93/230 (40%), Gaps = 38/230 (16%)
Query: 1243 PAVSKVLPAFRESPSGRLMRQDPVVHL--SPNKQGHSDSHYSSHSSSNTLSSNASSAHSD 1300
P +S+ F SP R HL S G S+ +SHS + + A
Sbjct: 117 PGLSEKSTTFYSSP-----RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA------ 165
Query: 1301 EKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVA 1360
+ G T L+ + +S G T+ P + +SLG ++ S PG
Sbjct: 166 ---FPGSTTMPGLSQESTASHSSP--GPTDTTLSPGSTTASSLGPEYTTFHSRPG----- 215
Query: 1361 PLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAA 1420
S+E + D T T S L+ S+ +HS +++ T L+ ST ++
Sbjct: 216 -----STETTLLPDNT--TASGLLEA------SMPVHSSTRSPHTTLSPAGSTTRQGEST 262
Query: 1421 SHTSTMSSRHS-ASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSG 1469
+ S SS+ + +P TSA P H +PS + + S+ S++SG
Sbjct: 263 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSH-GSPSSIPTTHISARSTTSG 311
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 53.1 bits (126), Expect = 2e-06
Identities = 57/220 (25%), Positives = 99/220 (45%), Gaps = 20/220 (9%)
Query: 1277 SDSHYSSHSSSNTLSSNASSAHSDEKWYDGD----RTESELNSYNYLQGTSADSGIDTTS 1332
S + +++S S+T+SS AS+A + E T SE + + GT+ +S TTS
Sbjct: 175 SGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTS 234
Query: 1333 YGP-----SHGSTASLGAAT------SSPRSGPGKEKVAPLWHSSSEVISMADRTLETES 1381
G S ST S GA T S+ SG G + SS + ++ + T S
Sbjct: 235 SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS 294
Query: 1382 HGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSAR 1441
G + T S S + +G+ T +S+ + + A++ T++ SS S+ T++
Sbjct: 295 SGANTATNSE-----SSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSE 349
Query: 1442 SSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATS 1481
SS A + + + SS +S+++ S GA++
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389
Score = 51.2 bits (121), Expect = 9e-06
Identities = 69/304 (22%), Positives = 125/304 (41%), Gaps = 15/304 (4%)
Query: 1277 SDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADS-GIDTTSYGP 1335
+++ S+++ S+ +SS AS+A + G S S + G+S S G+ +
Sbjct: 25 NETSTSANTGSSVISSGASTATNS-----GSSVTSSGVSTATISGSSVTSNGVSIVTNSE 79
Query: 1336 SHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLD 1395
H +++ + AT+S S SS S A +ES ++ + D
Sbjct: 80 FHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSD 139
Query: 1396 IHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQ 1455
+ S ST ++ST S ++A++ T++ SS S+ T++ SS A +
Sbjct: 140 SSTTSSGASTATNSDSSTTS-SEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198
Query: 1456 LAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAH 1515
+ + SS +S+++ S GA + E + S G S + A
Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTA-----TNSESSTTSSGASTATNSESSTPSSGAG 253
Query: 1516 TRLRA--STRDLRASPKPTSKS-TIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPS 1572
T + ST A S+S T+ + + + ES TP S + ++ SS S +
Sbjct: 254 TATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGAN 313
Query: 1573 TPTS 1576
T T+
Sbjct: 314 TATN 317
Score = 48.9 bits (115), Expect = 4e-05
Identities = 49/207 (23%), Positives = 85/207 (41%), Gaps = 19/207 (9%)
Query: 1282 SSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTA 1341
+++S S+T SS AS+A + E + + NS + + A + ++ S PS G+
Sbjct: 195 ATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGT 254
Query: 1342 SLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSL------- 1394
+ + +S+ SG G + SS + ++ + T S G + T S S
Sbjct: 255 ATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANT 314
Query: 1395 ----DIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHP 1450
D + S ST E+ST S + + S S+ S + S S+
Sbjct: 315 ATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTST 374
Query: 1451 AAPSQLAP--------SFSSSSSSSSG 1469
A S+ + + S SS++SSG
Sbjct: 375 ATNSESSTVSSGASTATTSESSTTSSG 401
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 50.4 bits (119), Expect = 2e-05
Identities = 118/515 (22%), Positives = 195/515 (37%), Gaps = 82/515 (15%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G P + LSPGS T SS+ +
Sbjct: 592 PGSTHTTAFPGSTTMPGLSQESTA--SHSSPG-PTDTTLSPGS---TTASSLGPEYTTFH 645
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+ P + ++ D + G + SMP S RSP + + G + SW
Sbjct: 646 SRPGSTETTLLPDNTTASGLL-EASMP--VHSSTRSPHTTLSPAGSTTRQGESTTFHSWP 702
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFVLEQHEYTE------PTCHLPAVSKVLPAFRESPSGR 1259
S D+ P S +E + PT H+ A R + SG
Sbjct: 703 SSNDTRP--------APPTTTSAFVEPSTTSHGSPSSIPTTHISA--------RSTTSG- 745
Query: 1260 LMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYL 1319
L+ + H SP H+ +++ ++++HS S ++ +
Sbjct: 746 LVEESTTYHSSPGST--QTMHFPESDTTSGRGEESTTSHS-----------STTHTISSA 792
Query: 1320 QGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLET 1379
T++ + TSY S GSTA+ SS SG +E +A HSS + T
Sbjct: 793 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIAS--HSSQDA---------T 841
Query: 1380 ESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTS 1439
+ L ++ +S+ L ++ ++P+ S+ S+ A ST + S F S
Sbjct: 842 GTIVLPARSTNSVLL-----GESTTSPI----SSGSMETTALPGSTTTPGLSERSTTFHS 892
Query: 1440 ARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGF 1499
+ SP L PA+ + S S++S S R G+T P+ T
Sbjct: 893 SPRSPATTLSPASTTSSGVSEESTTSHS--------RPGSTHTTAF----PDSTTTPGLS 940
Query: 1500 MDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFK 1559
+ H S G+ ++T L P + S+ + L + S+KS
Sbjct: 941 RHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 1000
Query: 1560 FHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQR 1594
F+ SSP+SP +T + +S+ES + R
Sbjct: 1001 FY--SSPRSP-DTTLSPASTTSSGVSEESTTSHSR 1032
Score = 48.9 bits (115), Expect = 4e-05
Identities = 99/423 (23%), Positives = 158/423 (37%), Gaps = 72/423 (17%)
Query: 1238 PTCHLPAVSKVLPAFRES------PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL- 1290
PT H A S L ES P P + S +++ S S+ T+
Sbjct: 377 PTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMH 436
Query: 1291 --SSNASSAHSDEK-WYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAAT 1347
S+ +S HS+E + G T ++ ++ S + + TSY S GST +
Sbjct: 437 FPESSTTSGHSEESATFHGSTTHTKSST------PSTTAALAHTSYHSSLGSTETTHFRD 490
Query: 1348 SSPRSGPGKEKVAPLWHSSSEVIS-------------MADRTLETESHGLDRKTE----- 1389
SS SG +E A HSS + ++ + D T S G T
Sbjct: 491 SSTISGRSEESKAS--HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST 548
Query: 1390 -----SSLSLDIHSKSQAGST---PLTRENSTFSINDAASHTSTMSSRHSASPVVFTSAR 1441
S S +S ++ T P + +S S SH+ S+ +A P T
Sbjct: 549 TKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 608
Query: 1442 SSPKEELHPAAPSQLAPSFS--SSSSSSSGPR--SFYPRQGATSKYLIGWKKPEGTINSV 1497
S + ++P + S S+++SS GP +F+ R G+T L+ P+ T S
Sbjct: 609 LSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLL----PDNTTAS- 663
Query: 1498 GFMD--------TRKRHQSDGNEIAHTRLRAST--------RDLRASPKPTSKSTIEEDL 1541
G ++ TR H + + TR ST D R +P T+ + +E
Sbjct: 664 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPST 723
Query: 1542 KKLIDLES-PTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTS 1600
S PT L + + S+P S + +H SD + + + E TS
Sbjct: 724 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT--SGRGEESTTS 781
Query: 1601 RAS 1603
+S
Sbjct: 782 HSS 784
Score = 45.1 bits (105), Expect = 6e-04
Identities = 76/368 (20%), Positives = 130/368 (35%), Gaps = 54/368 (14%)
Query: 1270 SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSAD 1325
S GHS+ SHS + +HS + G+ S + S + L G++
Sbjct: 135 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 194
Query: 1326 SGI---DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTL----- 1377
+G+ TT Y +L A ++ K + + I+ D T
Sbjct: 195 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 254
Query: 1378 --ETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENST--FSINDAASHTSTMSSRHSAS 1433
T SH + T+++LS + S G T +S +T+T +++
Sbjct: 255 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314
Query: 1434 PVVFTSARSSPKEELHPAAPS---------QLAPSFSSSSSSSSGPRSFYPRQGATSKYL 1484
PV S+ SP L PA+ + Q PS +S + SG S + + T
Sbjct: 315 PV--HSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYH-- 370
Query: 1485 IGWKKPEGT-INSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKST---IEE- 1539
P T T H + + + + +T +P P +T +EE
Sbjct: 371 ---SSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT-----TPPPARSATSGHVEES 422
Query: 1540 ----------DLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESI 1589
+ + + S++S FH S STP++ AL T S+
Sbjct: 423 TAYHRSPGSTQTMHFPESSTTSGHSEESATFH--GSTTHTKSSTPSTTAALAHTSYHSSL 480
Query: 1590 YNSQREHF 1597
+++ HF
Sbjct: 481 GSTETTHF 488
Score = 44.7 bits (104), Expect = 8e-04
Identities = 126/580 (21%), Positives = 209/580 (36%), Gaps = 65/580 (11%)
Query: 1048 YKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQVPSQVQSPMTSRLNAGKGDGKMPPPER 1107
Y + G + FP + + S HS + +P T+ + P
Sbjct: 753 YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 812
Query: 1108 AA--NIPRSISSDGRPLERRLS------PGSDIYVTVSSMALARSQCRNSPSNLSSSSDT 1159
A + P S ++ GR E S G+ + S+ ++ + SP + S S +T
Sbjct: 813 TATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPIS-SGSMET 871
Query: 1160 GSVGGTYRQKSMPEG---FGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMA 1216
++ G+ + E F S RSPA+ + + G S +ST S R +
Sbjct: 872 TALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGST------ 925
Query: 1217 YSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRE---------SPSGRLMRQDPVV 1267
++ P + L +H T + + +LPA SP + +
Sbjct: 926 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTAL 985
Query: 1268 HLSPNKQGHSD---SHYSSHSSSNTL---SSNASSAHSDEKWYDGDRTESELNSY----N 1317
S G S+ + YSS S +T +S SS S+E R S +
Sbjct: 986 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 1045
Query: 1318 YLQGTSADS-------GIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVI 1370
+ G S +S G T+ P + +SLG +++ SGPG E
Sbjct: 1046 TMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGST----------ETT 1095
Query: 1371 SMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRH 1430
+ D T T S L+ T +HS + + T L+ ST ++ + S SS+
Sbjct: 1096 LLPDNT--TASGLLEAST------PVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKD 1147
Query: 1431 S-ASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKK 1489
+ +P TSA H +PS + + S+SS++ G ++
Sbjct: 1148 TMPAPPTTTSAFVELSTTSH-GSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPS 1206
Query: 1490 PEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLES 1549
P + S ++ H S G+ +ST R+ TS S+ + S
Sbjct: 1207 PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTS 1266
Query: 1550 PTPESQKSFKFHALSSPQSPFP-STPTSRRALHRTLSDES 1588
E S+ S + FP S+ TS R+ T S S
Sbjct: 1267 ALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 1306
Score = 44.3 bits (103), Expect = 0.001
Identities = 78/309 (25%), Positives = 117/309 (37%), Gaps = 46/309 (14%)
Query: 1275 GHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSADSGI-- 1328
G S+ +SHSS + +++ A S GD T S ++S + L G++ G+
Sbjct: 496 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 555
Query: 1329 -DTTSY-GPSHGSTASLGAA-----------TSSPRSG-------PGKEKVAPLWHSSSE 1368
TT Y P T L A+ TS R G PG + L S+
Sbjct: 556 KSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 615
Query: 1369 VISMADRTLETESHGLDRKTESSLSLD---IHSKSQAGSTPLTRENSTFSINDAAS---H 1422
S T T S G T SSL + HS+ + T L +N+T S AS H
Sbjct: 616 SHSSPGPTDTTLSPG--STTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH 673
Query: 1423 TSTMSSRHSASPVVFTSARSS--------PKEELHPAAPSQ----LAPSFSSSSSSSSGP 1470
+ST S + SP T+ + + PA P+ + PS +S S SS P
Sbjct: 674 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIP 733
Query: 1471 RSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPK 1530
+ + TS + + S M + + G T +ST +S
Sbjct: 734 TTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP 793
Query: 1531 PTSKSTIEE 1539
T+ + +EE
Sbjct: 794 STTSALVEE 802
Score = 42.7 bits (99), Expect = 0.003
Identities = 88/384 (22%), Positives = 134/384 (34%), Gaps = 58/384 (15%)
Query: 1238 PTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQG------HSDSHYSSHSSSNTL- 1290
PT H A S ES + P SP + S +++SS S+ T+
Sbjct: 1174 PTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 1233
Query: 1291 --SSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGI--DTTSYGPSHGSTASLGAA 1346
S+ +S S+E RT ++ S S + + TSY S GS A+
Sbjct: 1234 FPESSTASGRSEES-----RTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP 1288
Query: 1347 TSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTP 1406
SS SG +E A HSS + + + G R ES+
Sbjct: 1289 ESSTTSGRSEESTAS--HSSPDTNGITPLPAHFTTSG--RIAEST--------------- 1329
Query: 1407 LTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSS 1466
T S S+ + T+T + S ++++S+RS P + L PA+ +SSS
Sbjct: 1330 -TFYISPGSMETTLASTATTPGLSAKSTILYSSSRS-PDQTLSPAS--------MTSSSI 1379
Query: 1467 SSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLR 1526
S P S Y + +T P T S ++ H G+ T S +
Sbjct: 1380 SGEPTSLYSQAESTHTTAF----PASTTTSGLSQESTTFHSKPGS----TETTLSPGSIT 1431
Query: 1527 ASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSD 1586
S +T + SP S LS + F S+P S + S+
Sbjct: 1432 TSSFAQEFTTPHSQPGSALSTVSPA-----STTVPGLSEESTTFYSSPGSTETTAFSHSN 1486
Query: 1587 ESIYNSQREHFFTSRASLLDQALP 1610
+SQ+ F LP
Sbjct: 1487 TMSIHSQQSTPFPDSPGFTHTVLP 1510
>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
Length = 861
Score = 50.4 bits (119), Expect = 2e-05
Identities = 100/387 (25%), Positives = 157/387 (40%), Gaps = 49/387 (12%)
Query: 1238 PTCHLPAVSKVLPAFRES------PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL- 1290
PT H A S L ES P P + S +++ S S+ T+
Sbjct: 312 PTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMH 371
Query: 1291 --SSNASSAHSDEK-WYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAAT 1347
S+ +S HS+E + G T ++ ++ S + + TSY S GST +
Sbjct: 372 FPESSTTSGHSEESATFHGSTTHTKSST------PSTTAALAHTSYHSSLGSTETTHFRD 425
Query: 1348 SSPRSGPGKEKVAPLWHSSSEVISMADRTL---ETESHGLDRKTESSLSL-DIHSKSQAG 1403
SS SG +E A HSS + +MA L T S + T S +S + + + G
Sbjct: 426 SSTISGRSEESKAS--HSSPD--AMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG 481
Query: 1404 STP---LTRENSTFSINDAASHTSTMSSRHSASPV--VFTSARSSPKEELHPAAP-SQLA 1457
ST L+ +++TF + + T+ + +R ++S V T++ S P A P S
Sbjct: 482 STTKPGLSEKSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTM 541
Query: 1458 PSF---SSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTI--NSVGFMDTR---KRHQSD 1509
P S++S SS GP G+T+ +G PE T +S G +T +
Sbjct: 542 PGLSQESTASHSSPGPTDTTLSPGSTTASSLG---PEYTTFHSSPGSTETTLLPDNTTAS 598
Query: 1510 GNEIAHTRLRASTRDLRASPKPT------SKSTIEEDLKKLIDLESPTPESQKSFKFHAL 1563
G A T + +STR + P +ST D P + +F +
Sbjct: 599 GLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 658
Query: 1564 SSPQSP--FPSTPTSRRALHRTLSDES 1588
+S SP P+T S R+ L +ES
Sbjct: 659 TSHGSPSSIPTTHISARSTTSGLVEES 685
Score = 45.1 bits (105), Expect = 6e-04
Identities = 90/359 (25%), Positives = 131/359 (36%), Gaps = 62/359 (17%)
Query: 1275 GHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSADSGI-- 1328
G S+ +SHSS + +++ A S GD T S ++S + L G++ G+
Sbjct: 431 GRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSE 490
Query: 1329 -DTTSY-GPSHGSTASLGA-----------ATSSPRSG-------PGKEKVAPLWHSSSE 1368
TT Y P T L A TS R G PG + L S+
Sbjct: 491 KSTTFYSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTA 550
Query: 1369 VISMADRTLETESHGLDRKTESSLSLD---IHSKSQAGSTPLTRENSTFSINDAAS---H 1422
S T T S G T SSL + HS + T L +N+T S AS H
Sbjct: 551 SHSSPGPTDTTLSPG--STTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVH 608
Query: 1423 TSTMSSRHSASPVVFTSARSS--------PKEELHPAAPSQ----LAPSFSSSSSSSSGP 1470
+ST S + SP T+ + ++ PA P+ + PS +S S SS P
Sbjct: 609 SSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 668
Query: 1471 RSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPK 1530
+ + TS G + ++ H S G+ + T R
Sbjct: 669 TTHISARSTTS----------GLVE-----ESTTYHSSPGSTQTMHFPESDTTSGRGEES 713
Query: 1531 PTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFP-STPTSRRALHRTLSDES 1588
TS S+ + S E S+ S+ + FP S+ TS R+ T S S
Sbjct: 714 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 772
Score = 43.9 bits (102), Expect = 0.001
Identities = 75/368 (20%), Positives = 130/368 (35%), Gaps = 54/368 (14%)
Query: 1270 SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY----LQGTSAD 1325
S GHS+ SHS + +HS + G+ S + S + L G++
Sbjct: 70 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 129
Query: 1326 SGI---DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTL----- 1377
+G+ TT Y +L A ++ K + + I+ D T
Sbjct: 130 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVS 189
Query: 1378 --ETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENST--FSINDAASHTSTMSSRHSAS 1433
T SH + T+++LS + S G T +S +T+T +++
Sbjct: 190 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 249
Query: 1434 PVVFTSARSSPKEELHPAAPS---------QLAPSFSSSSSSSSGPRSFYPRQGATSKYL 1484
PV S+ SP L P++ + Q PS +S + SG S + + T
Sbjct: 250 PV--HSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYH-- 305
Query: 1485 IGWKKPEGT-INSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKST---IEE- 1539
P T T H + + + + +T +P P +T +EE
Sbjct: 306 ---SSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT-----TPPPARSATSGHVEES 357
Query: 1540 ----------DLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESI 1589
+ + + S++S FH S STP++ AL T S+
Sbjct: 358 TAYHRSPGSTQTMHFPESSTTSGHSEESATFH--GSTTHTKSSTPSTTAALAHTSYHSSL 415
Query: 1590 YNSQREHF 1597
+++ HF
Sbjct: 416 GSTETTHF 423
>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
Length = 978
Score = 50.1 bits (118), Expect = 2e-05
Identities = 92/424 (21%), Positives = 160/424 (37%), Gaps = 56/424 (13%)
Query: 1082 PSQVQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMAL 1141
PS +S + + P + + P S ++ GR E R S S + T+SS
Sbjct: 234 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTH-TISSPPS 292
Query: 1142 ARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKST 1201
S P++ SS GS+ T+ PE S RS S ++ D G
Sbjct: 293 TTSALVEEPTSYHSS--PGSIATTH----FPESSTTSGRSEES-TASHSSPDTNGI-TPL 344
Query: 1202 PSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLM 1261
P+ + IA+ + Y P + + T T L A S +L + SP L
Sbjct: 345 PAHFTTSGRIAESTTF-YISPGSMETTLAS----TTTTPGLSAKSTILYSSSRSPDQTL- 398
Query: 1262 RQDPVVHLSPNKQGHSDSHYSSHSSSNT-----------LSSNASSAHSDEKWYDGDRTE 1310
P S + G S YS S++T LS +++ HS + +
Sbjct: 399 --SPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSP 456
Query: 1311 SELNSYNYLQGTS---ADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSS 1367
+ + ++ Q + + G ++ P+ + L +++ S PG + HS++
Sbjct: 457 GSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNT 516
Query: 1368 EVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMS 1427
I T +S G T + L + +T + +E++ F + A+ T+ +
Sbjct: 517 MSIHSQQSTPFPDSPGF---THTVLPATL------TTTDIGQESTAFHSSSDATGTTPLP 567
Query: 1428 SRHSAS-----PVVFTSARSSPKEELHPAAPS-----------QLAPSFSSSSSSSSGPR 1471
+R +AS P F + S L PA+ S +PSF+S+ S+
Sbjct: 568 ARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLE 627
Query: 1472 SFYP 1475
+ P
Sbjct: 628 TLAP 631
Score = 44.3 bits (103), Expect = 0.001
Identities = 119/541 (21%), Positives = 185/541 (34%), Gaps = 81/541 (14%)
Query: 1088 PMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCR 1147
P ++ A G MP + + S SS G + LSPGS T SS+ +
Sbjct: 62 PGSTHTTAFPGSTTMPGVSQESTA--SHSSPGST-DTTLSPGS---TTASSLGPESTTFH 115
Query: 1148 NSPSNLSSS--SDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQ 1205
+ P + ++ D + G + S + S T+ G + SW
Sbjct: 116 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ---GESTTFQSWP 172
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFV-----LEQHEYTEPTCHLPAVSKVLPAFRES----- 1255
S+D+ P ++FV + PT H A S L ES
Sbjct: 173 NSKDTTPAP-------PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 225
Query: 1256 -PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTL---SSNASSAHSDEKWYDGDRTES 1311
P P + S +++SS S+ T+ S+ +S S+E RT
Sbjct: 226 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES-----RTSH 280
Query: 1312 ELNSYNYLQGTSADSGI--DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEV 1369
++ S S + + TSY S GS A+ SS SG +E A HSS +
Sbjct: 281 SSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTAS--HSSPDT 338
Query: 1370 ISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSR 1429
+ + G R ES+ T S S+ + T+T
Sbjct: 339 NGITPLPAHFTTSG--RIAEST----------------TFYISPGSMETTLASTTTTPGL 380
Query: 1430 HSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKK 1489
+ S ++++S+RS P + L PA+ +SSS S P S Y + +T
Sbjct: 381 SAKSTILYSSSRS-PDQTLSPAS--------MTSSSISGEPTSLYSQAESTHTTAF---- 427
Query: 1490 PEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLES 1549
P T S ++ H G+ T S + S +T + S
Sbjct: 428 PASTTTSGLSQESTTFHSKPGS----TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVS 483
Query: 1550 PTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQAL 1609
P S LS + F S+P S + S+ +SQ+ F L
Sbjct: 484 PA-----STTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVL 538
Query: 1610 P 1610
P
Sbjct: 539 P 539
Score = 37.4 bits (85), Expect = 0.13
Identities = 69/313 (22%), Positives = 113/313 (36%), Gaps = 28/313 (8%)
Query: 1285 SSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADS-------GIDTTSYGPSH 1337
S ++T SS S + G + + G S +S G T+ P
Sbjct: 42 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS 101
Query: 1338 GSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIH 1397
+ +SLG +++ SGPG E + D T T S L+ T +H
Sbjct: 102 TTASSLGPESTTFHSGPGST----------ETTLLPDNT--TASGLLEAST------PVH 143
Query: 1398 SKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSA-SPVVFTSARSSPKEELHPAAPSQL 1456
S + + T L+ ST ++ + S +S+ + +P TSA H +PS
Sbjct: 144 SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSH-GSPSST 202
Query: 1457 APSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHT 1516
+ S+SS++ G ++ P + S ++ H S G+
Sbjct: 203 PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMH 262
Query: 1517 RLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFP-STPT 1575
+ST R+ TS S+ + S E S+ S + FP S+ T
Sbjct: 263 FPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTT 322
Query: 1576 SRRALHRTLSDES 1588
S R+ T S S
Sbjct: 323 SGRSEESTASHSS 335
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 48.1 bits (113), Expect = 8e-05
Identities = 91/359 (25%), Positives = 128/359 (35%), Gaps = 38/359 (10%)
Query: 1159 TGSVGGTYRQKSMPEGFGVSRR--SPASID-----RQNTQSDIGGSGKSTPSWQRSEDSI 1211
TG +G QK + EG G S S +D R T S+ G S K P ++ D+
Sbjct: 960 TGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKS-KDKPPKRKKADTE 1018
Query: 1212 ADQMAYSYR-----------GPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRL 1260
++S G + S Q T P P + K+ + P G +
Sbjct: 1019 GKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQ---TPPGVATPPIPKITI---QIPKGTV 1072
Query: 1261 MRQDPVVHLSPNKQGH-----SDSHYS-SHSSSNTLSSNASSAHSDEKWYDGDRTESELN 1314
M P H G S SH+S S SSS++ S++ S + + S +
Sbjct: 1073 MVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMY 1132
Query: 1315 SYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMAD 1374
S QG+S S +S S G S SG K+ P SS +
Sbjct: 1133 S---SQGSSGSSQSKNSS--QSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLS 1187
Query: 1375 RTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASP 1434
+ + SH R S L K G+ P ++ S S SH S SS
Sbjct: 1188 KPNISPSH--SRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKS 1245
Query: 1435 VVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGT 1493
+ S ++ P++ S A S S SSS SS S + K KKP T
Sbjct: 1246 SSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
Score = 37.7 bits (86), Expect = 0.10
Identities = 74/316 (23%), Positives = 111/316 (35%), Gaps = 61/316 (19%)
Query: 54 VGPPRSEGSHHITSTPGVPKMGVRARIADWPPRKENIKESSR--SSQEIETSSCLDSLSS 111
VG P S + TS+ V G ++ + + S + SS+ +SS S S
Sbjct: 1074 VGKPSSHSQY--TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSM 1131
Query: 112 KSSPVSQGSSVSLNSNDSA-------------MLKSIQNTLKNKTRPSENMDSRFLMPEA 158
SS S GSS S NS+ S S +K + +PS M+ P
Sbjct: 1132 YSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNI 1191
Query: 159 YPS------------SPRKALRRIRQRSNSDITISELDVDSFDECISPT----------- 195
PS SP K + S + IS S S +
Sbjct: 1192 SPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGS 1251
Query: 196 -----YKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPTPT------KLS 244
KT PS + S+SS G+S S + K R P+ KL
Sbjct: 1252 SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
Query: 245 DFLITGGGKGS-------GFSLDVIDGPISQRENL---RLFKEREKPLKRRSKSETGDSS 294
++T G G G S + P+S + N+ +REK K +SK T SS
Sbjct: 1312 HGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSS 1371
Query: 295 IFRKLRNAKGEELGKS 310
+ + ++ + +G +
Sbjct: 1372 VDSSKKTSESKNVGST 1387
Score = 35.8 bits (81), Expect = 0.39
Identities = 124/626 (19%), Positives = 218/626 (34%), Gaps = 100/626 (15%)
Query: 1026 PPHDDCTPRRSCS-ETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNASKGPHSPQVPSQ 1084
PPH P S + T P++ + + + +F + ++ ++N+S G SP++
Sbjct: 624 PPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSG--SPRMEIC 681
Query: 1085 VQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARS 1144
S T + + + + P + + R + S + +P D+ +T + L
Sbjct: 682 SGSNKTKKKKSSRLPPEKPKHQTEDDFQRELFSMDVDSQ---NPIFDVNMTADT--LDTP 736
Query: 1145 QCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSW 1204
+PS S+ T + Q S+ +S D + SDI PS
Sbjct: 737 HITPAPSQCSTPPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPST 796
Query: 1205 QRSEDSIA----DQMAYSYRGPQDFNSFVLE----QHEYTEPTCHLPAVSKVLPAFRESP 1256
+I D + + F+S V + ++ YT+P L A + P+ +SP
Sbjct: 797 SDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPA-DLIADAAGSPS-SDSP 854
Query: 1257 SGRLMRQ----DPVVHLSPNKQGHSDSHYSSHSSS--------------NTLSSNASSAH 1298
+ +P + S ++ G + ++ S S NTL
Sbjct: 855 TNHFFHDGVDFNPDLLNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGD 914
Query: 1299 SDEKWYDGDRTESELN------------------SYNYLQG---TSADSGIDTTSYGPSH 1337
+ E + G+ ++ ++ QG T+ D G + T
Sbjct: 915 NGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKE 974
Query: 1338 GSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIH 1397
G+ S +S SGPG + RT + D+ + + D
Sbjct: 975 GNGTS-----NSTLSGPGLDSKP----------GKRSRTPSNDGKSKDKPPKRKKA-DTE 1018
Query: 1398 SKSQAGST---PLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPS 1454
KS + S+ P T ST S + + A+P + PK + PS
Sbjct: 1019 GKSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPS 1078
Query: 1455 QLAPSFSSSSSSSSGPRSFYPRQGATSKYL-----IGWKKPEGTIN------------SV 1497
+ SS S SSSG +S + ++S + K EG+ + S
Sbjct: 1079 SHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSS 1138
Query: 1498 GFMDTRKRHQSDG----NEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPE 1553
G ++ QS G + I L + + + P+ S + L K S +
Sbjct: 1139 GSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRP 1198
Query: 1554 SQKSFKFHALSSPQSPFPSTPTSRRA 1579
S K L+SP P P TP S +A
Sbjct: 1199 PGGSDK---LASPMKPVPGTPPSSKA 1221
>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
Length = 587
Score = 47.4 bits (111), Expect = 1e-04
Identities = 96/415 (23%), Positives = 141/415 (33%), Gaps = 82/415 (19%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIP--RSISSDGRP--LERRLSPGSD 1131
P S P + TS + G D + P + P S +S P + LSPGS
Sbjct: 169 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS- 227
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + +SP + S++ +G V + R S G + SPAS
Sbjct: 228 --TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 284
Query: 1186 DRQNTQSDIGG------SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 285 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 332
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHS 1299
H PA S GHS+ HSS + + SSAHS
Sbjct: 333 THFPA-------------------------SSTTSGHSEKSTIFHSSPDASGTTPSSAHS 367
Query: 1300 DEKWYDGDRTES-------ELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRS 1352
+ + S ++ TS S TTS+ + A+L S P +
Sbjct: 368 TTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGT 427
Query: 1353 GPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENS 1412
+V+ +HS S S L R ES+ +H S GST T
Sbjct: 428 TAAPVEVSTTYHSRPS--STPTTHFSASSTTLGRSEEST---TVH--SSPGSTETT---- 476
Query: 1413 TFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSS 1467
A ST ++ S F S+ SP L PA+ + S S++S S
Sbjct: 477 -------ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 524
Score = 44.7 bits (104), Expect = 8e-04
Identities = 125/549 (22%), Positives = 195/549 (35%), Gaps = 89/549 (16%)
Query: 1110 NIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSDTGSVGGTYRQK 1169
+ P S ++ GR E S S + T+SS S P++ SS GS T+
Sbjct: 2 HFPESDTTSGRGEESTTSHSSTTH-TISSAPSTTSALVEEPTSYHSSP--GSTATTHFPD 58
Query: 1170 SMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFV 1229
S G S S AS Q+ I +ST S E + + +S
Sbjct: 59 SSTTS-GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSP-----------ISSGS 106
Query: 1230 LEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNT 1289
+E T P +S+ F SP P S S + +S S++T
Sbjct: 107 METTALPGSTT-TPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHT 165
Query: 1290 -----------LSSNASSAHSDEKWYDGDRTESELNSYNYLQ-GTSADSGIDTTSYGPSH 1337
LS +++++HS D + + Q T++ S +T S
Sbjct: 166 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 225
Query: 1338 GSTASL--GAATSSPRSGPGKEKVA--PLWHSSSEVISMADRTLETESHGLDRKT---ES 1390
GST +L G +++ S PG P +SS ++ + R S G R T S
Sbjct: 226 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV--HSSTGSPRTTLSPAS 283
Query: 1391 SLSLDIHSKSQA--------------------------------GSTPLTR--------- 1409
S S + +S A GSTP T
Sbjct: 284 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG 343
Query: 1410 --ENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSS 1467
E ST + + +T SS HS + V S SS + + P +++S S
Sbjct: 344 HSEKSTIFHSSPDASGTTPSSAHSTTSGV--SEESSTSHSQPGSTHTTAFPDSTTTSGLS 401
Query: 1468 SGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRA 1527
P + + QG+T L P GT + ++ + S + T AS+ L
Sbjct: 402 QEPTTSHSSQGSTEATLDTTPSPPGT--TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGR 459
Query: 1528 SPKPTS--KSTIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLS 1585
S + T+ S + L + S+KS F+ SSP+SP +T + +S
Sbjct: 460 SEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFY--SSPRSP-DTTLSPASTTSSGVS 516
Query: 1586 DESIYNSQR 1594
+ES + R
Sbjct: 517 EESTTSHSR 525
Score = 40.8 bits (94), Expect = 0.012
Identities = 76/320 (23%), Positives = 119/320 (37%), Gaps = 75/320 (23%)
Query: 1329 DTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEV-------------ISMADR 1375
+ TSY S GSTA+ SS SG +E A HSS + + + +
Sbjct: 40 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS--HSSQDATGTIVLPARSTTSVLLGES 97
Query: 1376 TLETESHGLDRKTE----------SSLSLDIHSKSQAGSTPL----------TRENSTFS 1415
T S G T S S HS ++ +T L + E++T
Sbjct: 98 TTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 157
Query: 1416 INDAASHTSTMS--------SRHSASPVVFTSARSSP---KEELHPAAPSQLAPSFSSSS 1464
++HT+ SRHS T++ SSP L PA+ + PS S++
Sbjct: 158 SRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTTSGPSQESTT 211
Query: 1465 S-SSSGPRSFYPRQGATSKYLIG-----WKKPEGTINSVGFMDTRKRHQSDGNEIAHTRL 1518
S SS G G+T+ G + G+ ++ F D+ S G A TR+
Sbjct: 212 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST---TSSGIVEASTRV 268
Query: 1519 RASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQK-SFKFHALSSPQSPFPSTPTSR 1577
+ST R + P S + SP + + +F+ H S+ +P P + +
Sbjct: 269 HSSTGSPRTTLSPASST-------------SPGLQGESTAFQTHPASTHTTPSPPSTATA 315
Query: 1578 RALHRTLSDESIYNSQREHF 1597
T S ++ HF
Sbjct: 316 PVEESTTYHRSPGSTPTTHF 335
>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
Length = 456
Score = 47.4 bits (111), Expect = 1e-04
Identities = 96/415 (23%), Positives = 141/415 (33%), Gaps = 82/415 (19%)
Query: 1076 PHSPQVPSQVQSPMTSRLNAGKGDGKMPPPERAANIP--RSISSDGRP--LERRLSPGSD 1131
P S P + TS + G D + P + P S +S P + LSPGS
Sbjct: 63 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGS- 121
Query: 1132 IYVTVSSMALARSQCRNSPSNL------SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASI 1185
T S + +SP + S++ +G V + R S G + SPAS
Sbjct: 122 --TTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST-GSPRTTLSPASS 178
Query: 1186 DRQNTQSDIGG------SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPT 1239
Q + S +TPS + + ++ +R P + PT
Sbjct: 179 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG------------STPT 226
Query: 1240 CHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHS 1299
H PA S GHS+ HSS + + SSAHS
Sbjct: 227 THFPA-------------------------SSTTSGHSEKSTIFHSSPDASGTTPSSAHS 261
Query: 1300 DEKWYDGDRTES-------ELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRS 1352
+ + S ++ TS S TTS+ + A+L S P +
Sbjct: 262 TTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGT 321
Query: 1353 GPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENS 1412
+V+ +HS S S L R ES+ +H S GST T
Sbjct: 322 TAAPVEVSTTYHSRPS--STPTTHFSASSTTLGRSEEST---TVH--SSPGSTETT---- 370
Query: 1413 TFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSS 1467
A ST ++ S F S+ SP L PA+ + S S++S S
Sbjct: 371 -------ALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 418
Score = 41.6 bits (96), Expect = 0.007
Identities = 93/406 (22%), Positives = 152/406 (37%), Gaps = 51/406 (12%)
Query: 1270 SPNKQGHSDSHYSSHSSSNTL---SSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADS 1326
+P HS + +SS S++T +S +S S E S + + T+
Sbjct: 68 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 127
Query: 1327 GIDTTSYGPSHGST---------ASLGAATSSPR----SGPGKEKVAPLWHSSSEVI--S 1371
G ++T++ S GST S G +S R +G + ++P +S + S
Sbjct: 128 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 187
Query: 1372 MADRTLETESHGLDRKTESSLSLDIHSKS---QAGSTPLTR-----------ENSTFSIN 1417
A +T +H ++ + S + GSTP T E ST +
Sbjct: 188 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 247
Query: 1418 DAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQ 1477
+ +T SS HS + V S SS + + P +++S S P + + Q
Sbjct: 248 SPDASGTTPSSAHSTTSGV--SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQ 305
Query: 1478 GATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTS--KS 1535
G+T L P GT + ++ + S + T AS+ L S + T+ S
Sbjct: 306 GSTEATLDTTPSPPGT--TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 363
Query: 1536 TIEEDLKKLIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQRE 1595
+ L + S+KS F+ SSP+SP +T + +S+ES + R
Sbjct: 364 PGSTETTALPGSTTTAGLSEKSTTFY--SSPRSP-DTTLSPASTTSSGVSEESTTSHSRP 420
Query: 1596 HFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLH 1641
S A P S+T P +P R Y LH
Sbjct: 421 ------GSTHTTAFPG----STTMPGYHSIIPWSRIYYLPQRPRLH 456
Score = 36.2 bits (82), Expect = 0.30
Identities = 64/269 (23%), Positives = 104/269 (38%), Gaps = 52/269 (19%)
Query: 1339 STASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHS 1398
+TA G+ T+ PG + + +HSS + T S G+
Sbjct: 3 TTALPGSTTT-----PGLSEKSTTFHSSPRSPATTLSPASTTSSGV-------------- 43
Query: 1399 KSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEE---LHPAAPSQ 1455
S+ +T +R ST + S T+ SRHS T++ SSP L PA+ +
Sbjct: 44 -SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS------TTSHSSPGSTDTTLLPASTTT 96
Query: 1456 LAPSFSSSSS-SSSGPRSFYPRQGATSKYLIG-----WKKPEGTINSVGFMDTRKRHQSD 1509
PS S++S SS G G+T+ G + G+ ++ F D+ S
Sbjct: 97 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST---TSS 153
Query: 1510 GNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQK-SFKFHALSSPQS 1568
G A TR+ +ST R + P S + SP + + +F+ H S+ +
Sbjct: 154 GIVEASTRVHSSTGSPRTTLSPASST-------------SPGLQGESTAFQTHPASTHTT 200
Query: 1569 PFPSTPTSRRALHRTLSDESIYNSQREHF 1597
P P + + T S ++ HF
Sbjct: 201 PSPPSTATAPVEESTTYHRSPGSTPTTHF 229
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 46.2 bits (108), Expect = 3e-04
Identities = 86/377 (22%), Positives = 139/377 (36%), Gaps = 56/377 (14%)
Query: 1297 AHSDEKWYDGDRTESEL-----NSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPR 1351
+H EK RT S L + + G S + T G S T LG +
Sbjct: 2264 SHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSIT--LGERRTITS 2321
Query: 1352 SGPGKEKVA-PLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRE 1410
+ P + + + +S+ + T S LD + + L D S S +T +
Sbjct: 2322 AAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASS 2381
Query: 1411 NSTFSINDAASHTSTMSSRHSASPVVFTSAR----SSPKEELHPAAPSQLAPSFSSSSSS 1466
+ + S TS S+SP +F+S R +S E +PS + ++S S
Sbjct: 2382 TMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGS 2441
Query: 1467 SSG--PRSFYP----RQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRA 1520
+ G P + P TS L+ W +P T +++ DT + T + A
Sbjct: 2442 NVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPA 2501
Query: 1521 --------STRD------LRASPKPTSKSTIEEDLK-----------KLIDLESPTPE-- 1553
ST D L+ SP + S + ++ ++ S T E
Sbjct: 2502 PGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEAS 2561
Query: 1554 ---SQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESIYNSQREHFFTSRASLLDQALP 1610
+ +S H SSPQ+ P+TPTS + + ES+ TS +L + L
Sbjct: 2562 LLTTSESKAIH--SSPQT--PTTPTSGANWETSATPESLLVVTE----TSDTTLTSKILV 2613
Query: 1611 NDVLFSSTYPSLPKSLP 1627
D + ST + P P
Sbjct: 2614 TDTILFSTVSTPPSKFP 2630
Score = 40.0 bits (92), Expect = 0.021
Identities = 128/586 (21%), Positives = 219/586 (37%), Gaps = 104/586 (17%)
Query: 1030 DCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNAS-KGPHSPQVPSQVQSP 1088
D + +S ++T+ + +E + + P + WQ + S + P S +PS + P
Sbjct: 7048 DTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGP--GDMSWQSSPSLENPSS--LPSLLSLP 7103
Query: 1089 MTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRN 1148
T+ PP ++ +P +ISS P+ L+ S T + + +
Sbjct: 7104 ATTS-----------PPPISSTLPVTISSSPLPVTSLLT--SSPVTTTDMLHTSPELVTS 7150
Query: 1149 SPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSE 1208
SP LS +SD G + + E S + AS +I SG +PS
Sbjct: 7151 SPPKLSHTSDERLTTG--KDTTNTEAVHPSTNTAAS------NVEIPSSGHESPS----- 7197
Query: 1209 DSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVH 1268
++AD P F+ E T V+ P F E+ ++++ +
Sbjct: 7198 SALADSETSKATSPM----FITSTQEDT-------TVAISTPHFLETSR---IQKESISS 7243
Query: 1269 LSPN--KQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADS 1326
LSP + G S S+ +S LS + A ++ RTE +S + G++ +
Sbjct: 7244 LSPKLRETGSSVETSSAIETSAVLSEVSIGATTEIS-----RTEVTSSSRTSISGSAEST 7298
Query: 1327 GIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDR 1386
+ P +T + K +P+ SSE+ T++T++
Sbjct: 7299 ML------PEISTTRKII-----------KFPTSPILAESSEM------TIKTQTSPPGS 7335
Query: 1387 KTESSLSLDIHSKSQAGSTP-LTRENSTFSINDAASHTSTMSSRH-------SASPVVFT 1438
+ES+ +LD +TP L +ST + S +T+ SR S+ PV T
Sbjct: 7336 TSESTFTLD------TSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEET 7389
Query: 1439 SARSSPKEELHPAAPSQLAPSF--SSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGT--- 1493
S SS +PS ++ + SS SSS+S P Q T++ L +PE +
Sbjct: 7390 SPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPP 7449
Query: 1494 ----------INSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKK 1543
S DT K H + +S + +S P S++T
Sbjct: 7450 SLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMG 7509
Query: 1544 LIDLESPTPESQKSFKFHALSSPQSPFPSTPTSRRALHRTLSDESI 1589
I + T S + QS S+ T+R T + S+
Sbjct: 7510 TISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSL 7555
Score = 38.9 bits (89), Expect = 0.046
Identities = 73/337 (21%), Positives = 127/337 (37%), Gaps = 37/337 (10%)
Query: 1135 TVSSMALARSQCRNS----PSNLSSSSDTGS----------VGGTYRQKSMPEGFGVSRR 1180
T S+ LA + N+ S L + SDT S TY +KS R
Sbjct: 1853 TSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRP 1912
Query: 1181 SPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTC 1240
++ + T + G+ + + S + + ++ D NS + T PT
Sbjct: 1913 ETSAPGAETTLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTI 1972
Query: 1241 HLPAVSKV----LPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASS 1296
+ + P S ++ +++ S +H +S SS ++ SS SS
Sbjct: 1973 VWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSS 2032
Query: 1297 AHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGK 1356
A + +S ++ N + D TTS + + SL A SS SG
Sbjct: 2033 ASLES-------LDSTISRRNAITSWLWDL---TTSLPTTTWPSTSLSEALSSGHSGVSN 2082
Query: 1357 EKVA----PLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTP----LT 1408
PL+ S++ + R ETE+HG S+L+ D S + TP ++
Sbjct: 2083 PSSTTTEFPLF-SAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASIS 2141
Query: 1409 RENSTFSINDAASHTSTMSSRHSASPVVFTSARSSPK 1445
E + S S ++S +A+P + T++ + K
Sbjct: 2142 SEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTK 2178
Score = 38.5 bits (88), Expect = 0.060
Identities = 89/445 (20%), Positives = 159/445 (35%), Gaps = 62/445 (13%)
Query: 1137 SSMALARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGG 1196
+S + S+ R SPS S G+ Y SM G S R T S G
Sbjct: 90 TSRGMTHSEQRTSPS--LSPQVNGTPSRNYPATSMVSGL--------SSPRTRTSSTEGN 139
Query: 1197 SGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPA-VSKVLPAFRES 1255
K ++ + ++ + + Y P + ++ + E T ++P ++ + F +S
Sbjct: 140 FTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADS 199
Query: 1256 PSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELN- 1314
+ + ++ V ++P + +DSH ++ + + +S K R E+ L
Sbjct: 200 TASK---ENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLEL 256
Query: 1315 -----SYNYLQGTSADSGIDTTSYGPSHGSTASL------------GAATSSPRSGPGKE 1357
Y + +G S S+AS+ G + +SP S E
Sbjct: 257 ILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPE 316
Query: 1358 KVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSIN 1417
A +S+ SM ET + + R T SSL S Q T LT +++
Sbjct: 317 ARASTMPNSAIPFSMTLSNAETSAERV-RSTISSLGTPSISTKQTAETILTFHAFAETMD 375
Query: 1418 DAASHTS-TMSSRHSASPVVFTSARSSPKEELHPAAP------------------SQLAP 1458
++H + T++S SP +S P+ L
Sbjct: 376 IPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNT 435
Query: 1459 SFSSSSSSSSGPRSFYPRQGATSKYLIGW-------KKPEGTINSVGFMDTRKRHQSDGN 1511
S + +S+ G S AT +G+ + P +S + R + G
Sbjct: 436 SMTPLETSAPGEES---EMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGR 492
Query: 1512 EIAHTRLRASTRDLRASPKPTSKST 1536
+ + T S+ LRA+ TSK++
Sbjct: 493 QSSSTAAHGSSDILRATTSSTSKAS 517
Score = 38.5 bits (88), Expect = 0.060
Identities = 126/603 (20%), Positives = 215/603 (35%), Gaps = 100/603 (16%)
Query: 1135 TVSSMALARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDI 1194
T SS A ++ S L +S+ T SV + EGF S+ + A +D+
Sbjct: 4683 TGSSGATSKIPLALDTSTLETSAGTPSV--------VTEGFAHSKITTAM------NNDV 4728
Query: 1195 GGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRE 1254
++ P +Q S + Q +F + H + P ++S VL +
Sbjct: 4729 KDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQWHSTSSPV----SMSSVLTSSLV 4784
Query: 1255 SPSGRLMRQDPVVHLSPNKQGHSDSHYS-----------SHSSSNTLSSNAS---SAHSD 1300
+G++ V SP ++ S +H S NT+ +N SA
Sbjct: 4785 KTAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFES 4844
Query: 1301 EKWYDGDRTESELNSYNYLQGTSADSGID----------------TTSYGPSHGSTASLG 1344
S++ S N T D+ I T+S P T+
Sbjct: 4845 HSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQ 4904
Query: 1345 AATSSPRSG--PGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQA 1402
TSS + P KE L +++EV S D T + S +S++SLDI +++
Sbjct: 4905 EITSSTETSTVPYKE----LTGATTEV-SRTDVT-SSSSTSFPGPDQSTVSLDISTETNT 4958
Query: 1403 --GSTPLTRENSTFSIN-DAASHTSTMSSRHSASPVVFTSARSSPKEELHPAA------- 1452
++P+ E++ +I H +T + P + ++P+ +H A
Sbjct: 4959 RLSTSPIMTESAEITITTQTGPHGATSQDTFTMDP-----SNTTPQAGIHSAMTHGFSQL 5013
Query: 1453 ---------PSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFMDTR 1503
P ++ + S +S P SF T+ LI PE ++S
Sbjct: 5014 DVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSS-PMTSLL 5072
Query: 1504 KRHQSDGNEIAHTRLRASTRDL----RASPKPTSKSTIEEDLKKL---IDLESPTPESQK 1556
+I TRL T L S K + S +D K++ I+ E ++
Sbjct: 5073 TSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANN 5132
Query: 1557 SFKFHALSSPQSPFPSTP--TSRRALHRTLSDESIYNSQREHFFTSRAS--------LLD 1606
S H SP TP T++ + T+ D + S H + + L
Sbjct: 5133 S--GHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTP 5190
Query: 1607 QALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPMPDPG 1666
+ S++P+ L + P+ T+ S G S+S S D ++ P G
Sbjct: 5191 RLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTG 5250
Query: 1667 LMP 1669
+P
Sbjct: 5251 EIP 5253
Score = 34.3 bits (77), Expect = 1.1
Identities = 75/350 (21%), Positives = 123/350 (35%), Gaps = 36/350 (10%)
Query: 1135 TVSSMALARSQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNT---- 1190
T + L + S L SS T T R+KS PE + S PA T
Sbjct: 3107 TAETQTLTFTPSETPTSLLPVSSPTEP---TARRKSSPETWASSISVPAKTSLVETTDGT 3163
Query: 1191 ------QSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPA 1244
S G ST W + A + G + ++ L+ EP+
Sbjct: 3164 LVTTIKMSSQAAQGNST--WPAPAEETGSSPAGTSPGSPEMST-TLKIMSSKEPSISPEI 3220
Query: 1245 VSKVLPAFRESPSGRLMRQDPV--VHLSPNKQGH---SDSHYSSHSSSNTLSSNASSAHS 1299
S V + ++P + + V V L G S SH + ++S T S + +
Sbjct: 3221 RSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLAT 3280
Query: 1300 DEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKV 1359
+ E+ N Y+ G + S +S SL + T+ +G G++
Sbjct: 3281 ERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSS--------VSLESPTARSITGTGQQ-- 3330
Query: 1360 APLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDA 1419
SS E++S + HG T + + + S P+T NS S+ D
Sbjct: 3331 -----SSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDK 3385
Query: 1420 ASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSG 1469
+ H + +A P + + E+ + + S SS S +SG
Sbjct: 3386 SKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSG 3435
Score = 33.1 bits (74), Expect = 2.5
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 19/194 (9%)
Query: 1323 SADSGIDTTSYGPSHGSTAS--LGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETE 1380
+++ G+ T S P +T S LGA SS K +A + S + ++ET
Sbjct: 1231 ASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYT-PLTFPSIETH 1289
Query: 1381 SHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFT-- 1438
H S + +S + E +T S D ++ +T + ++S V T
Sbjct: 1290 IH-------VSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQVSTPH 1342
Query: 1439 SARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVG 1498
S R+ E HP S ++S S SS P TS W + T +S
Sbjct: 1343 SVRTLRTTENHPKTESATPAAYSGSPKISSSP-------NLTSPATKAWTITDTTEHSTQ 1395
Query: 1499 FMDTRKRHQSDGNE 1512
T+ +S G E
Sbjct: 1396 LHYTKLAEKSSGFE 1409
Score = 31.2 bits (69), Expect = 9.5
Identities = 51/241 (21%), Positives = 86/241 (35%), Gaps = 36/241 (14%)
Query: 1275 GHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSAD--------- 1325
G S S ++ S S TL S ++ H G TE LN+ TSA
Sbjct: 398 GTSTSALTTTSPSTTLVSEETNTHHSTS---GKETEGTLNTSMTPLETSAPGEESEMTAT 454
Query: 1326 -------SGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLE 1378
+ +D+ PS S++ + S G++ + H SS+++ +
Sbjct: 455 LVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTS 514
Query: 1379 TESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFT 1438
S T S H++ S + E S + AA T+++ S S + T
Sbjct: 515 KASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKT 574
Query: 1439 SA----------------RSSPKEELHP-AAPSQLAPSFSSSSSSSSGPRSFYPRQGATS 1481
S+ S+ H A P+ ++ + SS+ S G R A+S
Sbjct: 575 SSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASS 634
Query: 1482 K 1482
+
Sbjct: 635 E 635
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 44.3 bits (103), Expect = 0.001
Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
Query: 977 VEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLR---TSVTVKVVIIPPH---DD 1030
V+ G AW+AGLR G L+E+ V + H Q+++++R ++ VKVV++ H D+
Sbjct: 705 VDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDE 764
Query: 1031 CTPRRSCSETYRMP 1044
+++ + R+P
Sbjct: 765 AVHKKAPQQAKRLP 778
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 43.9 bits (102), Expect = 0.001
Identities = 80/349 (22%), Positives = 118/349 (33%), Gaps = 38/349 (10%)
Query: 1144 SQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPS 1203
SQ +S + S +SDT SV G + + S R R +S GS S
Sbjct: 420 SQASDSEGH-SENSDTQSVSGHGKAGLRQQSHQESTRG-----RSGERSGRSGSSLYQVS 473
Query: 1204 WQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESP-SGRLMR 1262
DS + S G Q HE + A + R P S R R
Sbjct: 474 THEQPDSAHGRTGTSTGGRQG------SHHEQARDSSRHSASQEGQDTIRGHPGSSRGGR 527
Query: 1263 QDPVVHLSPNKQGHSDSHYS-------SHSSSNTLSSNASSAHSDEKWYDGDRTESELNS 1315
Q S N+ GHS SH+S S +S S ++S + + GD T +
Sbjct: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR 587
Query: 1316 YNYLQGTSADSGIDTTSYGPSHG--STASLGAATSSPRSGPGKEKVAPLW-------HSS 1366
++ + S G S G ++ + G++ S G + + W H
Sbjct: 588 HHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHG 647
Query: 1367 SEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTM 1426
S D + SH DR HS + + ++ S A+SH
Sbjct: 648 SAQEQSRDGSRHPRSHHEDRAGHG------HSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Query: 1427 SS---RHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRS 1472
SS RH + + ++ S H A S + S SS S S
Sbjct: 702 SSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDS 750
Score = 40.8 bits (94), Expect = 0.012
Identities = 42/167 (25%), Positives = 61/167 (36%), Gaps = 22/167 (13%)
Query: 1263 QDPVVHLSPNKQGHSDS------------HYSSHSSSNTLSSNASSAHSDEKWY----DG 1306
Q V + QGHS+ H S+ S S + S H D + D
Sbjct: 617 QGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADS 676
Query: 1307 DRTESELNSYNYLQGTSADSGIDT-TSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHS 1365
R ++ N G +A S +S G HGS L +A SS SG G + +
Sbjct: 677 SRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD 736
Query: 1366 SSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENS 1412
S S + ++E H D T+S + QAG + + S
Sbjct: 737 SGHRGSSGSQATDSEGHSEDSDTQS-----VSGHGQAGHHQQSHQES 778
Score = 40.0 bits (92), Expect = 0.021
Identities = 91/367 (24%), Positives = 134/367 (36%), Gaps = 50/367 (13%)
Query: 1144 SQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPS 1203
SQ +S + S SDT SV G + + S R DR +S GS S
Sbjct: 3338 SQASDSEGH-SEESDTQSVSGHGQAGPHQQSHQESAR-----DRSGGRSGRSGSFLYQVS 3391
Query: 1204 WQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESP-SGRLMR 1262
+S + S Q HE + A + R P S R R
Sbjct: 3392 THEQSESAHGRTRTSTGRRQG------SHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445
Query: 1263 QDPVVHLSPNKQGHSDSHYSSHSSSNTLS----------SNASSAHSDEKWYDGDRTESE 1312
Q S ++ GHS SH+ SH++S S S + +DE+ DG R
Sbjct: 3446 QGSHYEQSVDRSGHSGSHH-SHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW- 3503
Query: 1313 LNSYNYLQGTSADSGIDTTS-YGPSHG--STASLGAATSSPRSGPGKEKVAPLW------ 1363
S+++ T ADS + S G S G ++ + G++ S G + + W
Sbjct: 3504 --SHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 3561
Query: 1364 -HSSSEVISMADRTLETESHGLDR-----KTESSLSLDIH-----SKSQAGSTPLTRENS 1412
H S D + SH DR ESS H S QA S+ +S
Sbjct: 3562 NHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621
Query: 1413 TFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELH-PAAPSQLAPSFSSSSSSSSGPR 1471
+ + S SSRHS + A S+ ++ H ++ SQ + S S S +
Sbjct: 3622 AGERHGSHHQQSADSSRHSG--IGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV 3679
Query: 1472 SFYPRQG 1478
S + + G
Sbjct: 3680 SAHGQAG 3686
Score = 38.5 bits (88), Expect = 0.060
Identities = 89/371 (23%), Positives = 133/371 (35%), Gaps = 51/371 (13%)
Query: 1154 SSSSDTGSVGGTYRQKSMPEGFG-------VSRRSPASIDRQNTQSDIGG-----SGKST 1201
S+ D+G G + Q S EG VS A +Q+ Q G SG+S
Sbjct: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Query: 1202 PSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLM 1261
+ + A+ GP +HE + A + R P R
Sbjct: 3709 SFLYQVSTHEQSESAHGRAGPST-GGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRG 3767
Query: 1262 -RQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQ 1320
RQ S ++ GHS SH+S +S S+AS S G R+ S
Sbjct: 3768 GRQGSYHEQSVDRSGHSGSHHSHTTSQG--RSDASHGQS------GSRSASRETR----- 3814
Query: 1321 GTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETE 1380
SG + G H ++ ++ +SG G+ + +S D E
Sbjct: 3815 -NEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQ-DSDSEAY 3872
Query: 1381 SHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSA 1440
+R++ES+ S + H S+ S +R + S D ASH +SPV S
Sbjct: 3873 PEDSERRSESA-SRNHHGSSREQSRDGSRHPGS-SHRDTASHV-------QSSPV--QSD 3921
Query: 1441 RSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATSKYLIGWKKPEGTINSVGFM 1500
S+ KE H ++ SQ + S S S P ++ Y + EGT G
Sbjct: 3922 SSTAKEHGHFSSLSQDSAYHSGIQSRGS------PHSSSSYHY-----QSEGTERQKGQS 3970
Query: 1501 DTRKRHQSDGN 1511
RH S G+
Sbjct: 3971 GLVWRHGSYGS 3981
Score = 37.0 bits (84), Expect = 0.17
Identities = 98/407 (24%), Positives = 143/407 (35%), Gaps = 78/407 (19%)
Query: 1098 GDGKMPPPERAANIPRSISSDGRPL-----ERRLSPGSDIYVTVSSMALARSQCRNSPSN 1152
G G R + P + +S G + R SPG + + + + S+ P
Sbjct: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPG-ERHGSRHQQSADSSRHSGIPRR 1052
Query: 1153 LSSSS--DTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDS 1210
+SS+ D+G G + Q S EG + +TQS + G G+ P Q ++S
Sbjct: 1053 QASSAVRDSGHWGSSGSQASDSEGHS---------EESDTQS-VSGHGQDGPHQQSHQES 1102
Query: 1211 IADQMAYSYRGPQDFNSFVLE------------------------QHEYTEPTCHLPAVS 1246
D +S SF+ + HE + A
Sbjct: 1103 ARD---WSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 1159
Query: 1247 KVLPAFRESPSGRLM-RQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYD 1305
+ R P R RQ S ++ GHS SH+S +S S+AS S
Sbjct: 1160 EGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQG--RSDASHGQS------ 1211
Query: 1306 GDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHS 1365
G R+ S SG + G H AS A SS S G+E+ + +
Sbjct: 1212 GSRSASRQTR------KDKQSGDGSRHSGSRHHEAASW--ADSSRHSQVGQEQSSGS-RT 1262
Query: 1366 SSEVISMADRTLETESHGLD-RKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASH-- 1422
S S + ++E H D + S S + H S+ S +R + F D ASH
Sbjct: 1263 SRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSR-HPGFHQEDRASHGH 1321
Query: 1423 ----------TSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPS 1459
T SS H + ARSSP E H + Q A S
Sbjct: 1322 SADSSRQSGTHHTESSSHGQAVSSHEQARSSPGER-HGSRHQQSADS 1367
Score = 36.6 bits (83), Expect = 0.23
Identities = 80/342 (23%), Positives = 126/342 (36%), Gaps = 34/342 (9%)
Query: 1144 SQCRNSPSNLSSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPS 1203
SQ +S + S SDT SV G + + S R DR +S GS S
Sbjct: 745 SQATDSEGH-SEDSDTQSVSGHGQAGHHQQSHQESAR-----DRSGERSRRSGSFLYQVS 798
Query: 1204 WQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESP-SGRLMR 1262
+ +S ++ + GP HE A R P S R R
Sbjct: 799 THKQSES-----SHGWTGPST-GVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGR 852
Query: 1263 QDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGT 1322
Q S ++ GHS SH+ SH++S S D R +S S +
Sbjct: 853 QGSHHEQSVDRSGHSGSHH-SHTTSQGRS-------------DASRGQSGSRSASRTTRN 898
Query: 1323 SADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESH 1382
S + G H +S + ++G G+ + + +S S + ++E H
Sbjct: 899 EEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGS---RTSRRQGSSVSQDSDSEGH 955
Query: 1383 GLD-RKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVFTSA- 1440
D + S S + +Q S +R + + A S SSR S +P TS+
Sbjct: 956 SEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSG 1015
Query: 1441 -RSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATS 1481
+++ E ++P + S S+ SS S PR+ A+S
Sbjct: 1016 GQAASSHEQARSSPGERHGSRHQQSADSS-RHSGIPRRQASS 1056
Score = 36.2 bits (82), Expect = 0.30
Identities = 82/358 (22%), Positives = 125/358 (34%), Gaps = 76/358 (21%)
Query: 1154 SSSSDTGSVGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIAD 1213
S+ D+G G + Q S EG + +TQS + GK+ P Q ++S
Sbjct: 2029 SAVRDSGHRGYSGSQASDSEGHS---------EDSDTQS-VSAQGKAGPHQQSHKESARG 2078
Query: 1214 QMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVS----------KVLPAFRESPS------ 1257
Q S F + + HE +E T A S + + R S S
Sbjct: 2079 QSGESSGRSGSF-LYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDT 2137
Query: 1258 -------GRLMRQDPVVHLSPNKQGHSDSHYS---SHSSSNTLSSNASSAHSDEKWYDGD 1307
R RQ S ++ GHS SH+S S S+ + S + K YD +
Sbjct: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKE 2197
Query: 1308 RT---ESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWH 1364
++ S+++ + ADS S G S G TS PR
Sbjct: 2198 QSGDGSRHSGSHHHEASSWADS-----SRHSLVGQGQSSGPRTSRPRG------------ 2240
Query: 1365 SSSEVISMADRTLETESHGLDRKTES-SLSLDIHSKSQAGSTPLTRENSTFSINDAASHT 1423
S + ++E H D + S S S + H +Q S +R + + H
Sbjct: 2241 ------SSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR-------HPRSHHE 2287
Query: 1424 STMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPRQGATS 1481
HSA S+R S ++ Q A S + SS+ + +Q A S
Sbjct: 2288 DRAGHGHSAE-----SSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340
Score = 35.8 bits (81), Expect = 0.39
Identities = 44/196 (22%), Positives = 74/196 (37%), Gaps = 24/196 (12%)
Query: 1263 QDPVVHLSPNKQGHSDS--HYSSHSSSNTLSS----------NASSAHSDEKWY----DG 1306
Q V + QGHS+ +S +S N L S + S H D + D
Sbjct: 1914 QGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADS 1973
Query: 1307 DRTESELNSYNYLQGTSADSGIDT-TSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHS 1365
R ++ + +G +A S +S G HGS L +A SS SG G + +
Sbjct: 1974 SRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRD 2033
Query: 1366 SSEVISMADRTLETESHGLDRKTESSLS-------LDIHSKSQAGSTPLTRENSTFSIND 1418
S + ++E H D T+S + H +S G + + S +
Sbjct: 2034 SGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQ 2093
Query: 1419 AASHTSTMSSRHSASP 1434
++H + S+ ++P
Sbjct: 2094 VSTHEQSESTHGQSAP 2109
Score = 34.7 bits (78), Expect = 0.86
Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 23/169 (13%)
Query: 1262 RQDPVVHLSPNKQGHSD-----------SHYSSHSSSNTLSSNASSAHSDEKWYDGDRTE 1310
RQ V + +GHS+ +HY S + S +H +++ G E
Sbjct: 1589 RQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAE 1648
Query: 1311 SELNSYNYLQGTSADSGIDTT------SYGPSHGSTASLGAATSSPRSGPGKEKVAPLWH 1364
S S TS+ ++ S G HGS +A SS SG G+ + + +
Sbjct: 1649 SSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQ-SADSSTDSGTGRRQDSSVVG 1707
Query: 1365 SSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENST 1413
S S + ++E H + T+S + + QAG + + ST
Sbjct: 1708 DSGNRGSSGSQASDSEGHSEESDTQS-----VSAHGQAGPHQQSHQEST 1751
Score = 33.5 bits (75), Expect = 1.9
Identities = 81/365 (22%), Positives = 126/365 (34%), Gaps = 52/365 (14%)
Query: 1151 SNLSSSSDTGSVGGTYRQKSMPEG--FGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSE 1208
S+ + S G G++ Q+S G+ +S R + GS +++ S SE
Sbjct: 2318 SHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS-QASDSEGHSE 2376
Query: 1209 DSIADQM-AYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESPSGRLMRQDPVV 1267
DS + A+ GP Q + E T + A R SG + Q
Sbjct: 2377 DSDTQSVSAHGQAGPH--------QQSHQEST-------RGRSAGRSGRSGSFLYQVSTH 2421
Query: 1268 HLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEK-------WYDGDRTESELNS-YNYL 1319
S + G + + S+ + SS HS + + G + S Y L
Sbjct: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQL 2481
Query: 1320 QGTSADSGID---TTSYG---PSHGSTASLGAA---TSSPRSGPGKEKVAPLWHSSSEVI 1370
S SG TTS G SHG + S A+ + +SG G H +S
Sbjct: 2482 VDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRA 2541
Query: 1371 SMADRTL----ETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSIN--------- 1417
+ + ++E R SS S D S SQ S R + + S N
Sbjct: 2542 DSSGHSQVGQGQSEGPRTSRNWGSSFSQD--SDSQGHSEDSERWSGSASRNHHGSAQEQL 2599
Query: 1418 -DAASHTSTMSSRHSASPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGPRSFYPR 1476
D + H + + S+R S ++ Q A S + SS+ + +
Sbjct: 2600 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQ 2659
Query: 1477 QGATS 1481
Q A S
Sbjct: 2660 QSADS 2664
Score = 33.1 bits (74), Expect = 2.5
Identities = 75/347 (21%), Positives = 123/347 (35%), Gaps = 43/347 (12%)
Query: 1158 DTGSVGGTYRQKSMPEGFG-------VSRRSPASIDRQNTQSDIGG-----SGKSTPSWQ 1205
D+G+ G + Q S EG VS A +Q+ Q G SG+S
Sbjct: 1708 DSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLY 1767
Query: 1206 RSEDSIADQMAYSYRGPQDFNSFVLEQHEYTEPTCHLPAVSKVLPAFRESP-SGRLMRQD 1264
+ + A+ GP +HE + A + R P S R RQ
Sbjct: 1768 QVSTHEQSESAHGRTGPST-GGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 1826
Query: 1265 PVVHLSPNKQGHSDSHYSSHSSS--NTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGT 1322
S + GHS SH+S +S + +S S + S + ++ + + ++ +
Sbjct: 1827 SHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH 1886
Query: 1323 SADSGIDTTSY-----GPSHG--STASLGAATSSPRSGPGKEKVAPLW-------HSSSE 1368
A S D++ + G S G ++ + G++ S G + + W H S
Sbjct: 1887 EASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSA 1946
Query: 1369 VISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSS 1428
D + SH DR HS + + S+ A+SH SS
Sbjct: 1947 WEQSRDGSRHPGSHHEDRAGHG------HSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
Query: 1429 ---RHSASPVVFTSARSSPKEELHPAAPSQLAPS----FSSSSSSSS 1468
RH + + ++ S H A S + S +S S +S S
Sbjct: 2001 AGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDS 2047
Score = 33.1 bits (74), Expect = 2.5
Identities = 39/175 (22%), Positives = 64/175 (36%), Gaps = 29/175 (16%)
Query: 1256 PSGRLMRQDPVVHLSPNKQGHSDS------------HYSSHSSSNTLSSNASSAHSDEKW 1303
P G + QD + +GHS+ H S+ S S + S H D
Sbjct: 2238 PRGSSVSQDS------DSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAG 2291
Query: 1304 YDGDRTESELNSYNYLQGTSADSGIDT-----TSYGPSHGSTASLGAATSSPRSGPGKEK 1358
+ S + ++ + +S + +S G HGS +A SS SG G +
Sbjct: 2292 HGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ-SADSSRHSGIGHGQ 2350
Query: 1359 VAPLWHSSSEVISMADRTLETESHGLDRKTESSLSLDIHSKSQAGSTPLTRENST 1413
+ S S + ++E H D T+S + + QAG + + ST
Sbjct: 2351 ASSAVRDSGHRGSSGSQASDSEGHSEDSDTQS-----VSAHGQAGPHQQSHQEST 2400
Score = 33.1 bits (74), Expect = 2.5
Identities = 53/222 (23%), Positives = 89/222 (40%), Gaps = 21/222 (9%)
Query: 1270 SPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNY-LQGTSADS-- 1326
S +G S S +S ++ N S SS HS + ++ T ++++ ++ +QG S S
Sbjct: 3149 SDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEAS-THADISRHSQAVQGQSEGSRR 3207
Query: 1327 --------GIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLE 1378
D+ S G S S G+A+ + R ++ H S A
Sbjct: 3208 SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAG---- 3263
Query: 1379 TESHGLDRKTES-SLSLDIHSKSQAGSTPLTRENSTFSINDAASHTSTMSSRHSASPVVF 1437
H DR +S + + S QA S+ +S + + S SSRHS P
Sbjct: 3264 -HGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP--R 3320
Query: 1438 TSARSSPKEELH-PAAPSQLAPSFSSSSSSSSGPRSFYPRQG 1478
A S+ ++ H ++ SQ + S S S + S + + G
Sbjct: 3321 GQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAG 3362
Score = 31.6 bits (70), Expect = 7.3
Identities = 48/201 (23%), Positives = 69/201 (34%), Gaps = 33/201 (16%)
Query: 1278 DSHYSSHSS-SNTLSSNASSAH---SDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSY 1333
DS HS S LS +AS H S E+ DG R G SADS + ++
Sbjct: 1273 DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTH 1332
Query: 1334 ---GPSHGSTASLG-----------------AATSSPRSGPGKEKVAPLWHSSSEVISMA 1373
SHG S +A SS SG G + + S S
Sbjct: 1333 HTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSG 1392
Query: 1374 DRTLETESHGLDRKTESSLS-------LDIHSKSQAGSTPLTRENSTFSINDAASHTSTM 1426
+ +E H D T+S + H +S G + + S + +SH +
Sbjct: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
Query: 1427 SSRHSASPVVFTSARSSPKEE 1447
S+ +P T R + E
Sbjct: 1453 STHGQTAP--STGGRQGSRHE 1471
Score = 31.2 bits (69), Expect = 9.5
Identities = 44/187 (23%), Positives = 62/187 (33%), Gaps = 11/187 (5%)
Query: 1177 VSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMAYSYRGPQDFNSFVLEQHEYT 1236
+S R D + D +G+ T W +S IA +S + E Y
Sbjct: 200 LSERLEEKEDNEEGVYDYENTGRMTQKWIQS-GHIATYYTIQDEAYDTTDSLLEENKIYE 258
Query: 1237 EPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSS-SNTLSSNAS 1295
S + R + ++ Q+ + D HS S S +AS
Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSAS 318
Query: 1296 SAHSDEKWY---DGDRTESELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSS--- 1349
H W DG R + G SADS + G H T+S G SS
Sbjct: 319 RNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQS---GTRHAETSSRGQTASSHEQ 375
Query: 1350 PRSGPGK 1356
RS PG+
Sbjct: 376 ARSSPGE 382
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,036,867
Number of Sequences: 37866
Number of extensions: 3497197
Number of successful extensions: 15017
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 314
Number of HSP's that attempted gapping in prelim test: 13218
Number of HSP's gapped (non-prelim): 1703
length of query: 1804
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1687
effective length of database: 13,817,196
effective search space: 23309609652
effective search space used: 23309609652
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.