Guide to the Human Genome
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Name: FLG Sequence: fasta or formatted (4061aa) NCBI GI: 60097902
Description:

filaggrin

Referenced in:

Calmodulin and Calcium
Polymorphism
Skin and Related Tissues

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.1        246           2
 C cysteine            0.0          2           1
 D aspartate           5.5        222           2
 E glutamate           6.3        256           3
 F phenylalanine       0.6         24           1
 G glycine            12.8        518           2
 H histidine          10.2        413           3
 I isoleucine          0.9         38           2
 K lysine              1.4         57           2
 L leucine             1.1         43           2
 M methionine          0.1          5           1
 N asparagine          1.5         62           2
 P proline             1.7         69           1
 Q glutamine           9.0        367           2
 R arginine           10.8        440           2
 S serine             24.1        977           4
 T threonine           4.1        166           2
 V valine              2.0         83           2
 W tryptophan          0.5         21           1
 Y tyrosine            1.3         52           4
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   filaggrin 
HRNR                  0.104   hornerin 
FLG2                  0.089   filaggrin family member 2 
DSPP                  0.029   dentin sialophosphoprotein preproprotein 
MUC12                 0.024   PREDICTED: mucin 12 
SRRM2                 0.019   splicing coactivator subunit SRm300 
RPTN                  0.018   repetin 
RBMXL3                0.015   RNA binding motif protein, X-linked-like 3 
TCHH                  0.012   trichohyalin 
NKTR                  0.012   natural killer-tumor recognition sequence 
MUC12                 0.011   PREDICTED: mucin 12, cell surface associated 
ZC3H13                0.010   zinc finger CCCH-type containing 13 
CRNN                  0.010   cornulin 
LOC100292370          0.009   PREDICTED: hypothetical protein 
GPATCH8               0.009   G patch domain containing 8 
LOC100170229          0.009   hypothetical protein LOC100170229 
C2orf16               0.009   hypothetical protein LOC84226 
HRC                   0.009   histidine rich calcium binding protein precursor [Hom...
DMP1                  0.008   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
MUC21                 0.008   mucin 21 
TCHHL1                0.008   trichohyalin-like 1 
RP1L1                 0.008   retinitis pigmentosa 1-like 1 
KIAA1853              0.008   KIAA1853 protein 
MUC12                 0.008   PREDICTED: mucin 12 
RPGR                  0.008   retinitis pigmentosa GTPase regulator isoform C [Hom...
FLJ37078              0.008   hypothetical protein LOC222183 
MED1                  0.007   mediator complex subunit 1 
AFF4                  0.007   ALL1 fused gene from 5q31 
TCOF1                 0.007   Treacher Collins-Franceschetti syndrome 1 isoform e...
SFRS4                 0.007   splicing factor, arginine/serine-rich 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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