Guide to the Human Genome
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Name: TSC2 Sequence: fasta or formatted (1807aa) NCBI GI: 116256352
Description:

tuberous sclerosis 2 isoform 1

Referenced in:

mTOR Pathway
Ras

Other entries for this name:
alt prot [1740aa] tuberous sclerosis 2 isoform 4
alt prot [1784aa] tuberous sclerosis 2 isoform 5
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2        131           2
 C cysteine            2.0         37           1
 D aspartate           4.5         81           2
 E glutamate           6.8        122           3
 F phenylalanine       3.4         61           2
 G glycine             5.3         96           2
 H histidine           2.7         49           2
 I isoleucine          4.2         76           3
 K lysine              4.6         83           2
 L leucine            12.3        222           4
 M methionine          1.9         34           2
 N asparagine          3.0         54           2
 P proline             6.3        113           3
 Q glutamine           3.9         71           2
 R arginine            6.4        116           2
 S serine             10.1        182           4
 T threonine           4.4         79           2
 V valine              7.6        137           2
 W tryptophan          0.8         15           1
 Y tyrosine            2.7         48           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tuberous sclerosis 2 isoform 1 
TSC2                  0.983   tuberous sclerosis 2 isoform 5 
TSC2                  0.954   tuberous sclerosis 2 isoform 4 
GARNL1                0.021   GTPase activating Rap/RanGAP domain-like 1 isoform 2...
C20orf74              0.021   akt substrate AS250 
GARNL1                0.021   GTPase activating Rap/RanGAP domain-like 1 isoform 1...
RAP1GAP               0.013   RAP1 GTPase activating protein isoform c 
RAP1GAP               0.013   RAP1 GTPase activating protein isoform a 
RAP1GAP               0.013   RAP1 GTPase activating protein isoform b 
GARNL4                0.012   GTPase activating Rap/RanGAP domain-like 4 isoform ...
GARNL4                0.012   GTPase activating Rap/RanGAP domain-like 4 isoform ...
GARNL3                0.012   GTPase activating Rap/RanGAP domain-like 3 
SIPA1L2               0.012   signal-induced proliferation-associated 1 like 2 [H...
SIPA1                 0.011   signal-induced proliferation-associated protein 1 [...
SIPA1                 0.011   signal-induced proliferation-associated protein 1 [...
SIPA1L1               0.011   signal-induced proliferation-associated 1 like 1 [Hom...
SIPA1L3               0.011   signal-induced proliferation-associated 1 like 3 [Ho...
SRRM2                 0.004   splicing coactivator subunit SRm300 
COL14A1               0.004   collagen, type XIV, alpha 1 
SEC24B                0.004   SEC24 (S. cerevisiae) homolog B isoform a 
REXO1                 0.004   transcription elongation factor B polypeptide 3 bin...
TTC28                 0.004   tetratricopeptide repeat domain 28 
MLL                   0.004   myeloid/lymphoid or mixed-lineage leukemia protein [...
HDAC7                 0.003   histone deacetylase 7 isoform a 
LOC100292113          0.003   PREDICTED: hypothetical protein XP_002345530 
LOC100290048          0.003   PREDICTED: hypothetical protein XP_002348148 
LOC100288945          0.003   PREDICTED: hypothetical protein XP_002343821 
SORBS2                0.003   sorbin and SH3 domain containing 2 isoform 6 
SORBS2                0.003   sorbin and SH3 domain containing 2 isoform 4 
LDB3                  0.003   LIM domain binding 3 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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