Guide to the Human Genome
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Name: TSC2 Sequence: fasta or formatted (1740aa) NCBI GI: 116256350
Description:

tuberous sclerosis 2 isoform 4

Referenced in:

mTOR Pathway
Ras

Other entries for this name:
alt prot [1807aa] tuberous sclerosis 2 isoform 1
alt prot [1784aa] tuberous sclerosis 2 isoform 5
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2        125           2
 C cysteine            2.0         35           1
 D aspartate           4.7         81           2
 E glutamate           6.8        118           3
 F phenylalanine       3.3         58           2
 G glycine             5.4         94           2
 H histidine           2.7         47           2
 I isoleucine          4.3         74           3
 K lysine              4.6         80           2
 L leucine            12.5        218           4
 M methionine          2.0         34           2
 N asparagine          3.0         52           2
 P proline             6.3        109           3
 Q glutamine           3.9         67           2
 R arginine            6.3        110           2
 S serine              9.6        167           4
 T threonine           4.5         79           2
 V valine              7.5        131           2
 W tryptophan          0.8         14           1
 Y tyrosine            2.7         47           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tuberous sclerosis 2 isoform 4 
TSC2                  0.994   tuberous sclerosis 2 isoform 5 
TSC2                  0.990   tuberous sclerosis 2 isoform 1 
GARNL1                0.022   GTPase activating Rap/RanGAP domain-like 1 isoform 2...
C20orf74              0.022   akt substrate AS250 
GARNL1                0.022   GTPase activating Rap/RanGAP domain-like 1 isoform 1...
RAP1GAP               0.014   RAP1 GTPase activating protein isoform c 
RAP1GAP               0.014   RAP1 GTPase activating protein isoform a 
RAP1GAP               0.014   RAP1 GTPase activating protein isoform b 
GARNL4                0.013   GTPase activating Rap/RanGAP domain-like 4 isoform ...
GARNL4                0.013   GTPase activating Rap/RanGAP domain-like 4 isoform ...
GARNL3                0.012   GTPase activating Rap/RanGAP domain-like 3 
SIPA1L2               0.012   signal-induced proliferation-associated 1 like 2 [H...
SIPA1                 0.012   signal-induced proliferation-associated protein 1 [...
SIPA1                 0.012   signal-induced proliferation-associated protein 1 [...
SIPA1L1               0.012   signal-induced proliferation-associated 1 like 1 [Hom...
SIPA1L3               0.011   signal-induced proliferation-associated 1 like 3 [Ho...
HDAC7                 0.005   histone deacetylase 7 isoform a 
WNK4                  0.005   WNK lysine deficient protein kinase 4 
COL14A1               0.005   collagen, type XIV, alpha 1 
REXO1                 0.005   transcription elongation factor B polypeptide 3 bin...
MAP1A                 0.004   microtubule-associated protein 1A 
SRRM2                 0.004   splicing coactivator subunit SRm300 
SEC24B                0.004   SEC24 (S. cerevisiae) homolog B isoform a 
TNRC18                0.004   trinucleotide repeat containing 18 
ETV3                  0.004   ets variant gene 3 isoform 1 
YEATS2                0.004   YEATS domain containing 2 
NACA                  0.004   nascent polypeptide-associated complex alpha subuni...
SMTNL1                0.004   smoothelin-like 1 
PGR                   0.004   progesterone receptor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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