Guide to the Human Genome
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Search of human proteins with 7019485

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7019485 programmed cell death 6 [Homo sapiens]
         (191 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7019485 programmed cell death 6 [Homo sapiens]                     396   e-111
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]           135   2e-32
gi|4507207 sorcin isoform a [Homo sapiens]                            119   1e-27
gi|38679884 sorcin isoform b [Homo sapiens]                           115   3e-26
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap...   108   4e-24
gi|14161692 calpain small subunit 2 [Homo sapiens]                     92   4e-19
gi|47078247 calpain 3 isoform f [Homo sapiens]                         81   6e-16
gi|4557405 calpain 3 isoform a [Homo sapiens]                          81   6e-16
gi|27765072 calpain 3 isoform b [Homo sapiens]                         81   6e-16
gi|27765076 calpain 3 isoform d [Homo sapiens]                         81   6e-16
gi|27765074 calpain 3 isoform c [Homo sapiens]                         80   1e-15
gi|4502565 calpain, small subunit 1 [Homo sapiens]                     79   2e-15
gi|51599151 calpain, small subunit 1 [Homo sapiens]                    79   2e-15
gi|27765080 calpain 3 isoform e [Homo sapiens]                         78   5e-15
gi|27765078 calpain 3 isoform e [Homo sapiens]                         78   5e-15
gi|12408656 calpain 1, large subunit [Homo sapiens]                    69   2e-12
gi|7705383 calpain 9 isoform 2 [Homo sapiens]                          69   3e-12
gi|5729758 calpain 9 isoform 1 [Homo sapiens]                          69   3e-12
gi|157389005 calpain 2 isoform 1 [Homo sapiens]                        66   2e-11
gi|225703100 calpain 2 isoform 2 [Homo sapiens]                        66   2e-11
gi|4885111 calmodulin-like 3 [Homo sapiens]                            66   2e-11
gi|221554549 calpain 8 [Homo sapiens]                                  65   3e-11
gi|223278387 calmodulin-like 5 [Homo sapiens]                          64   8e-11
gi|215490104 calpain 11 [Homo sapiens]                                 63   2e-10
gi|58218968 calmodulin 3 [Homo sapiens]                                59   3e-09
gi|4502549 calmodulin 2 [Homo sapiens]                                 59   3e-09
gi|5901912 calmodulin 1 [Homo sapiens]                                 59   3e-09
gi|239755174 PREDICTED: similar to solute carrier family 25, mem...    54   6e-08
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ...    54   6e-08
gi|38707981 calpain 12 [Homo sapiens]                                  53   1e-07

>gi|7019485 programmed cell death 6 [Homo sapiens]
          Length = 191

 Score =  396 bits (1017), Expect = e-111
 Identities = 191/191 (100%), Positives = 191/191 (100%)

Query: 1   MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPF 60
           MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPF
Sbjct: 1   MAAYSYRPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPF 60

Query: 61  NPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS 120
           NPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS
Sbjct: 61  NPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALS 120

Query: 121 GFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY 180
           GFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY
Sbjct: 121 GFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSY 180

Query: 181 EQYLSMVFSIV 191
           EQYLSMVFSIV
Sbjct: 181 EQYLSMVFSIV 191


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score =  135 bits (340), Expect = 2e-32
 Identities = 74/175 (42%), Positives = 104/175 (59%), Gaps = 6/175 (3%)

Query: 19  GAALPD---QSFLWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRE 75
           G A P+   +++ W  FQ VD D SG IS  EL+QAL N  W+ FN  T   +I+MFD+ 
Sbjct: 109 GGAPPNVDPEAYSW--FQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKT 166

Query: 76  NKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILI 135
               ++   F+ +WK+I  W+N+F+ YDRD SG I   EL+QALS  GY LS QF  +L+
Sbjct: 167 KSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLV 226

Query: 136 RKF-DRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFS 189
            ++  R     +  D FIQ C  LQ LT+ FR  DT   G I++S+E +++M  S
Sbjct: 227 SRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281


>gi|4507207 sorcin isoform a [Homo sapiens]
          Length = 198

 Score =  119 bits (299), Expect = 1e-27
 Identities = 73/200 (36%), Positives = 108/200 (54%), Gaps = 15/200 (7%)

Query: 3   AYSYRPGPGAG--PGPAAGA----ALPDQSF--LWNVFQRVDKDRSGVISDTELQQALSN 54
           AY   PG G G  PG   GA    A P Q+   L+  F  V   + G I   ELQ+ L+ 
Sbjct: 2   AYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAV-AGQDGQIDADELQRCLTQ 60

Query: 55  ----GTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMI 110
               G + PFN  T R ++SM DR+    + F+EF  +W  +  W+  F ++D D SG +
Sbjct: 61  SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 120

Query: 111 DKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDT 170
           D  EL++AL+  G+RLS Q  + + +++   G+  I FDD+I  C+ L+ LTD FRR DT
Sbjct: 121 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRRDT 178

Query: 171 DQDGWIQVSYEQYLSMVFSI 190
            Q G +   Y+ ++  V S+
Sbjct: 179 AQQGVVNFPYDDFIQCVMSV 198


>gi|38679884 sorcin isoform b [Homo sapiens]
          Length = 183

 Score =  115 bits (287), Expect = 3e-26
 Identities = 67/186 (36%), Positives = 102/186 (54%), Gaps = 12/186 (6%)

Query: 11  GAGPGPAAGAALPDQSF--LWNVFQRVDKDRSGVISDTELQQALSN----GTWTPFNPVT 64
           G  PG   G A P Q+   L+  F  V   + G I   ELQ+ L+     G + PFN  T
Sbjct: 4   GGAPG---GPAFPGQTQDPLYGYFAAV-AGQDGQIDADELQRCLTQSGIAGGYKPFNLET 59

Query: 65  VRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGY 124
            R ++SM DR+    + F+EF  +W  +  W+  F ++D D SG +D  EL++AL+  G+
Sbjct: 60  CRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGF 119

Query: 125 RLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYL 184
           RLS Q  + + +++   G+  I FDD+I  C+ L+ LTD FRR DT Q G +   Y+ ++
Sbjct: 120 RLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFI 177

Query: 185 SMVFSI 190
             V S+
Sbjct: 178 QCVMSV 183


>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
           sapiens]
          Length = 217

 Score =  108 bits (269), Expect = 4e-24
 Identities = 55/156 (35%), Positives = 91/156 (58%), Gaps = 6/156 (3%)

Query: 39  RSGVISDTELQQALS----NGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITD 94
           + G +   ELQ+ L+    NGT++PF+  T R +I+M DR++   + F+ F  +W  +  
Sbjct: 64  QDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNA 123

Query: 95  WQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQG 154
           W+  F T D+D SG ++ +EL+QA+   GYRLS Q    +++++ + GR  I FDD++  
Sbjct: 124 WKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGR--IFFDDYVAC 181

Query: 155 CIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190
           C+ L+ LTD FR+ D  Q G     Y+ +L    +I
Sbjct: 182 CVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI 217



 Score = 27.7 bits (60), Expect = 6.3
 Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 3/77 (3%)

Query: 32  FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKY 91
           F  VD+D SG +   EL+QA+    +   +P T+ +I+  + +  +  + F ++      
Sbjct: 128 FMTVDQDGSGTVEHHELRQAIGLMGYR-LSPQTLTTIVKRYSKNGR--IFFDDYVACCVK 184

Query: 92  ITDWQNVFRTYDRDNSG 108
           +    + FR  D    G
Sbjct: 185 LRALTDFFRKRDHLQQG 201


>gi|14161692 calpain small subunit 2 [Homo sapiens]
          Length = 248

 Score = 91.7 bits (226), Expect = 4e-19
 Identities = 43/127 (33%), Positives = 78/127 (61%), Gaps = 1/127 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F+  T RSI+S+ D +    + F EF  +W  I  WQ V++ YDRD+SG +  ++L+ AL
Sbjct: 119 FSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGAL 178

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
              G++L++Q + +++R++  +  G + F++FI   + L  +   F+  D D+DG IQVS
Sbjct: 179 QAAGFQLNEQLYQMIVRRYANED-GDMDFNNFISCLVRLDAMFRAFKSLDRDRDGLIQVS 237

Query: 180 YEQYLSM 186
            +++L +
Sbjct: 238 IKEWLQL 244


>gi|47078247 calpain 3 isoform f [Homo sapiens]
          Length = 728

 Score = 80.9 bits (198), Expect = 6e-16
 Identities = 51/187 (27%), Positives = 94/187 (50%), Gaps = 10/187 (5%)

Query: 7   RPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGT-------WTP 59
           +  P   PG +   +   Q F  N+F+++  D   + +D EL++ L+             
Sbjct: 541 KQSPQPQPGSSDQESEEQQQFR-NIFKQIAGDDMEICAD-ELKKVLNTVVNKHKDLKTHG 598

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 599 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 658

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 659 NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 717

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 718 VLEWLQL 724


>gi|4557405 calpain 3 isoform a [Homo sapiens]
          Length = 821

 Score = 80.9 bits (198), Expect = 6e-16
 Identities = 51/187 (27%), Positives = 94/187 (50%), Gaps = 10/187 (5%)

Query: 7   RPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGT-------WTP 59
           +  P   PG +   +   Q F  N+F+++  D   + +D EL++ L+             
Sbjct: 634 KQSPQPQPGSSDQESEEQQQFR-NIFKQIAGDDMEICAD-ELKKVLNTVVNKHKDLKTHG 691

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 692 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 751

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 752 NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 810

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 811 VLEWLQL 817


>gi|27765072 calpain 3 isoform b [Homo sapiens]
          Length = 815

 Score = 80.9 bits (198), Expect = 6e-16
 Identities = 51/187 (27%), Positives = 94/187 (50%), Gaps = 10/187 (5%)

Query: 7   RPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGT-------WTP 59
           +  P   PG +   +   Q F  N+F+++  D   + +D EL++ L+             
Sbjct: 628 KQSPQPQPGSSDQESEEQQQFR-NIFKQIAGDDMEICAD-ELKKVLNTVVNKHKDLKTHG 685

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 686 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 745

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 746 NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 804

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 805 VLEWLQL 811


>gi|27765076 calpain 3 isoform d [Homo sapiens]
          Length = 309

 Score = 80.9 bits (198), Expect = 6e-16
 Identities = 51/187 (27%), Positives = 94/187 (50%), Gaps = 10/187 (5%)

Query: 7   RPGPGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGT-------WTP 59
           +  P   PG +   +   Q F  N+F+++  D   + +D EL++ L+             
Sbjct: 122 KQSPQPQPGSSDQESEEQQQFR-NIFKQIAGDDMEICAD-ELKKVLNTVVNKHKDLKTHG 179

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 180 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 239

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 240 NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 298

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 299 VLEWLQL 305


>gi|27765074 calpain 3 isoform c [Homo sapiens]
          Length = 729

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 51/184 (27%), Positives = 93/184 (50%), Gaps = 10/184 (5%)

Query: 10  PGAGPGPAAGAALPDQSFLWNVFQRVDKDRSGVISDTELQQALSNGT-------WTPFNP 62
           P   PG +   +   Q F  N+F+++  D   + +D EL++ L+             F  
Sbjct: 545 PVPQPGSSDQESEEQQQFR-NIFKQIAGDDMEICAD-ELKKVLNTVVNKHKDLKTHGFTL 602

Query: 63  VTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGF 122
            + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A++  
Sbjct: 603 ESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDA 662

Query: 123 GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQ 182
           G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++  +
Sbjct: 663 GFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLE 721

Query: 183 YLSM 186
           +L +
Sbjct: 722 WLQL 725


>gi|4502565 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 37/123 (30%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 64  TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
           T RS++++ D +    + F EF  +W  I  WQ +++ +D D SG I  +EL  A    G
Sbjct: 143 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAG 202

Query: 124 YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQY 183
           + L++  ++++IR++  +  G + FD+FI   + L  +   F+  D D  G IQV+ +++
Sbjct: 203 FHLNEHLYNMIIRRYSDES-GNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261

Query: 184 LSM 186
           L +
Sbjct: 262 LQL 264



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 9/94 (9%)

Query: 27  FLWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAG 79
           +LWN       ++++ D DRSG I  +EL  A     +   N      II  +  E+   
Sbjct: 166 YLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGF-HLNEHLYNMIIRRYSDES-GN 223

Query: 80  VNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKN 113
           ++F  F      +      F++ D+D +G I  N
Sbjct: 224 MDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257


>gi|51599151 calpain, small subunit 1 [Homo sapiens]
          Length = 268

 Score = 79.0 bits (193), Expect = 2e-15
 Identities = 37/123 (30%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 64  TVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFG 123
           T RS++++ D +    + F EF  +W  I  WQ +++ +D D SG I  +EL  A    G
Sbjct: 143 TCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAG 202

Query: 124 YRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQY 183
           + L++  ++++IR++  +  G + FD+FI   + L  +   F+  D D  G IQV+ +++
Sbjct: 203 FHLNEHLYNMIIRRYSDES-GNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEW 261

Query: 184 LSM 186
           L +
Sbjct: 262 LQL 264



 Score = 33.1 bits (74), Expect = 0.15
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 9/94 (9%)

Query: 27  FLWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAG 79
           +LWN       ++++ D DRSG I  +EL  A     +   N      II  +  E+   
Sbjct: 166 YLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGF-HLNEHLYNMIIRRYSDES-GN 223

Query: 80  VNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKN 113
           ++F  F      +      F++ D+D +G I  N
Sbjct: 224 MDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVN 257


>gi|27765080 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 39/127 (30%), Positives = 70/127 (55%), Gaps = 1/127 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 27  FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 87  NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 145

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 146 VLEWLQL 152



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 28  LWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV 80
           LWN       +F+  D D+SG I+  E++ A+++  +   N   +  II+M   +    +
Sbjct: 55  LWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN--QLYDIITMRYADKHMNI 112

Query: 81  NFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELK 116
           +F  F   +  +      F  +D+D  G+I  N L+
Sbjct: 113 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLE 148


>gi|27765078 calpain 3 isoform e [Homo sapiens]
          Length = 156

 Score = 77.8 bits (190), Expect = 5e-15
 Identities = 39/127 (30%), Positives = 70/127 (55%), Gaps = 1/127 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F   + RS+I++ D +    +N  EF  +W  I  WQ +F+ YD D SG I+  E++ A+
Sbjct: 27  FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
           +  G+ L++Q +DI+  ++       I FD FI   + L+ +   F  +D D DG I+++
Sbjct: 87  NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 145

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 146 VLEWLQL 152



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 9/96 (9%)

Query: 28  LWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV 80
           LWN       +F+  D D+SG I+  E++ A+++  +   N   +  II+M   +    +
Sbjct: 55  LWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN--QLYDIITMRYADKHMNI 112

Query: 81  NFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELK 116
           +F  F   +  +      F  +D+D  G+I  N L+
Sbjct: 113 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLE 148


>gi|12408656 calpain 1, large subunit [Homo sapiens]
          Length = 714

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 31/127 (24%), Positives = 70/127 (55%), Gaps = 1/127 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F+  + RS++++ DR+    +   EF  +W  I ++ ++FR +D D SG +   E++ A+
Sbjct: 585 FSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAI 644

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
              G++L+ + ++++I ++       + FD+F+   + L+ +   F+  DTD DG +   
Sbjct: 645 ESAGFKLNKKLYELIITRYSEPDLA-VDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFD 703

Query: 180 YEQYLSM 186
             ++L +
Sbjct: 704 LFKWLQL 710


>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
          Length = 664

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 32/128 (25%), Positives = 66/128 (51%), Gaps = 1/128 (0%)

Query: 63  VTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGF 122
           ++ ++IIS+ D      + F EF   W  +  W N+F  +D D SG +   EL+ AL   
Sbjct: 538 ISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAA 597

Query: 123 GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQ 182
           G++LS     +++ ++  +   Q+ FDDF+   + L+  + +F+   T    +I ++  +
Sbjct: 598 GFQLSSHLLQLIVLRYADE-ELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINE 656

Query: 183 YLSMVFSI 190
           ++ +  +I
Sbjct: 657 FIHLTMNI 664



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 30  NVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVW 89
           N+F R D D+SG +S  EL+ AL    +   + +    ++   D E +  ++F +F    
Sbjct: 572 NLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQ--LDFDDFLNCL 629

Query: 90  KYITDWQNVFRTYDRDNSGMIDKN 113
             + +   VF+     N   I  N
Sbjct: 630 VRLENASRVFQALSTKNKEFIHLN 653


>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
          Length = 690

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 32/128 (25%), Positives = 66/128 (51%), Gaps = 1/128 (0%)

Query: 63  VTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGF 122
           ++ ++IIS+ D      + F EF   W  +  W N+F  +D D SG +   EL+ AL   
Sbjct: 564 ISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAA 623

Query: 123 GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQ 182
           G++LS     +++ ++  +   Q+ FDDF+   + L+  + +F+   T    +I ++  +
Sbjct: 624 GFQLSSHLLQLIVLRYADE-ELQLDFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINE 682

Query: 183 YLSMVFSI 190
           ++ +  +I
Sbjct: 683 FIHLTMNI 690



 Score = 29.3 bits (64), Expect = 2.2
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 2/84 (2%)

Query: 30  NVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVW 89
           N+F R D D+SG +S  EL+ AL    +   + +    ++   D E +  ++F +F    
Sbjct: 598 NLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQ--LDFDDFLNCL 655

Query: 90  KYITDWQNVFRTYDRDNSGMIDKN 113
             + +   VF+     N   I  N
Sbjct: 656 VRLENASRVFQALSTKNKEFIHLN 679


>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
          Length = 700

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 33/125 (26%), Positives = 67/125 (53%), Gaps = 1/125 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F+  T + ++ M D +    +   EF  +W  I  +Q ++R  D D SG ++  E+++AL
Sbjct: 572 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 631

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
              G+++  Q H +++ +F    +  I FD+F++  + L+ L  IF++ D +  G I++ 
Sbjct: 632 EEAGFKMPCQLHQVIVARF-ADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 690

Query: 180 YEQYL 184
              +L
Sbjct: 691 LISWL 695


>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
          Length = 622

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 33/125 (26%), Positives = 67/125 (53%), Gaps = 1/125 (0%)

Query: 60  FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
           F+  T + ++ M D +    +   EF  +W  I  +Q ++R  D D SG ++  E+++AL
Sbjct: 494 FSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKAL 553

Query: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
              G+++  Q H +++ +F    +  I FD+F++  + L+ L  IF++ D +  G I++ 
Sbjct: 554 EEAGFKMPCQLHQVIVARF-ADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELD 612

Query: 180 YEQYL 184
              +L
Sbjct: 613 LISWL 617


>gi|4885111 calmodulin-like 3 [Homo sapiens]
          Length = 149

 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 39/129 (30%), Positives = 66/129 (51%), Gaps = 8/129 (6%)

Query: 32  FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVW-K 90
           F   DKD  G I+  EL   + +    P     +R ++S  DR+    V+F EF G+  +
Sbjct: 17  FSLFDKDGDGCITTRELGTVMRSLGQNP-TEAELRDMMSEIDRDGNGTVDFPEFLGMMAR 75

Query: 91  YITDWQN------VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRG 144
            + D  N       FR +D+D +G +   EL+  ++  G +LSD+  D +IR  D  G G
Sbjct: 76  KMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDG 135

Query: 145 QIAFDDFIQ 153
           Q+ +++F++
Sbjct: 136 QVNYEEFVR 144



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 92  ITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151
           +T+++  F  +D+D  G I   EL   +   G   ++     ++ + DR G G + F +F
Sbjct: 10  VTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEF 69

Query: 152 IQGCIVLQRLTD-------IFRRYDTDQDGWIQVS 179
           +       + TD        FR +D D +G++  +
Sbjct: 70  LGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAA 104


>gi|221554549 calpain 8 [Homo sapiens]
          Length = 703

 Score = 65.5 bits (158), Expect = 3e-11
 Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 4/143 (2%)

Query: 48  LQQALSNGT---WTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDR 104
           L +A S  T   +  FN  T R +IS+ D      +   EF  +W  I  +  ++   D 
Sbjct: 560 LNEAFSKRTDIKFDGFNINTCREMISLLDSNGTGTLGAVEFKTLWLKIQKYLEIYWETDY 619

Query: 105 DNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDI 164
           ++SG ID +E++ AL   G+ L+ Q    +  ++     G I FD F+   I L+ L  +
Sbjct: 620 NHSGTIDAHEMRTALRKAGFTLNSQVQQTIALRYACSKLG-INFDSFVACMIRLETLFKL 678

Query: 165 FRRYDTDQDGWIQVSYEQYLSMV 187
           F   D D+DG +Q+S  ++L  V
Sbjct: 679 FSLLDEDKDGMVQLSLAEWLCCV 701


>gi|223278387 calmodulin-like 5 [Homo sapiens]
          Length = 146

 Score = 63.9 bits (154), Expect = 8e-11
 Identities = 42/139 (30%), Positives = 69/139 (49%), Gaps = 6/139 (4%)

Query: 18  AGAALPDQSFLWN-VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDREN 76
           AG   P++   +   F  VD D +G I+  EL  AL   T    +   +R +IS  D + 
Sbjct: 2   AGELTPEEEAQYKKAFSAVDTDGNGTINAQELGAALK-ATGKNLSEAQLRKLISEVDSDG 60

Query: 77  KAGVNFSEFTGVWKY----ITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHD 132
              ++F EF    K     + D Q  FR +D+D  G I  +EL++A++G G  L  +  D
Sbjct: 61  DGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELD 120

Query: 133 ILIRKFDRQGRGQIAFDDF 151
            +IR+ D    G++ +++F
Sbjct: 121 AMIREADVDQDGRVNYEEF 139


>gi|215490104 calpain 11 [Homo sapiens]
          Length = 739

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 33/121 (27%), Positives = 63/121 (52%), Gaps = 1/121 (0%)

Query: 66  RSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYR 125
           R +I++ D++    +   EF  +WK +  W ++FR  D+D+SG ++  E++  +   G +
Sbjct: 616 RCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIK 675

Query: 126 LSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLS 185
           L+++   +L+ ++       I FD FI   + L+ +   F   D    G I +S EQ+L 
Sbjct: 676 LNNKVMQVLVARYADDDL-IIDFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQ 734

Query: 186 M 186
           M
Sbjct: 735 M 735


>gi|58218968 calmodulin 3 [Homo sapiens]
          Length = 149

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 36/129 (27%), Positives = 66/129 (51%), Gaps = 8/129 (6%)

Query: 32  FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF-TGVWK 90
           F   DKD  G I+  EL   + +    P     ++ +I+  D +    ++F EF T + +
Sbjct: 17  FSLFDKDGDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

Query: 91  YITDWQN------VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRG 144
            + D  +       FR +D+D +G I   EL+  ++  G +L+D+  D +IR+ D  G G
Sbjct: 76  KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDG 135

Query: 145 QIAFDDFIQ 153
           Q+ +++F+Q
Sbjct: 136 QVNYEEFVQ 144


>gi|4502549 calmodulin 2 [Homo sapiens]
          Length = 149

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 36/129 (27%), Positives = 66/129 (51%), Gaps = 8/129 (6%)

Query: 32  FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF-TGVWK 90
           F   DKD  G I+  EL   + +    P     ++ +I+  D +    ++F EF T + +
Sbjct: 17  FSLFDKDGDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

Query: 91  YITDWQN------VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRG 144
            + D  +       FR +D+D +G I   EL+  ++  G +L+D+  D +IR+ D  G G
Sbjct: 76  KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDG 135

Query: 145 QIAFDDFIQ 153
           Q+ +++F+Q
Sbjct: 136 QVNYEEFVQ 144


>gi|5901912 calmodulin 1 [Homo sapiens]
          Length = 149

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 36/129 (27%), Positives = 66/129 (51%), Gaps = 8/129 (6%)

Query: 32  FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEF-TGVWK 90
           F   DKD  G I+  EL   + +    P     ++ +I+  D +    ++F EF T + +
Sbjct: 17  FSLFDKDGDGTITTKELGTVMRSLGQNP-TEAELQDMINEVDADGNGTIDFPEFLTMMAR 75

Query: 91  YITDWQN------VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRG 144
            + D  +       FR +D+D +G I   EL+  ++  G +L+D+  D +IR+ D  G G
Sbjct: 76  KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDG 135

Query: 145 QIAFDDFIQ 153
           Q+ +++F+Q
Sbjct: 136 QVNYEEFVQ 144


>gi|239755174 PREDICTED: similar to solute carrier family 25, member
           25 isoform 1 [Homo sapiens]
          Length = 503

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 2   AAYSYRPGPGAGPGPAAGAAL--PDQSF-LWNVFQRVDKDRSGVISDTELQQALSNGTWT 58
           AA S    P +   P  GA    PD    LW +FQ +D +R G +   +L   L      
Sbjct: 21  AASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRR-LGL 79

Query: 59  PFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQN----VFRTYDRDNSGMIDKNE 114
                 ++ I+   D++    ++F EF     Y+ D +     VF++ D+ N G ID  E
Sbjct: 80  HRTEGELQKIVQAGDKDLDGQLDFEEFV---HYLQDHEKKLRLVFKSLDKKNDGRIDAQE 136

Query: 115 LKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151
           + Q+L   G ++S+Q  + +++  D+ G   I ++++
Sbjct: 137 IMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEW 173



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 98  VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIV 157
           +F+T D +  G +  N+L   L   G   ++     +++  D+   GQ+ F++F+     
Sbjct: 53  LFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVH---Y 109

Query: 158 LQ----RLTDIFRRYDTDQDGWI 176
           LQ    +L  +F+  D   DG I
Sbjct: 110 LQDHEKKLRLVFKSLDKKNDGRI 132


>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
           sapiens]
          Length = 503

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 11/157 (7%)

Query: 2   AAYSYRPGPGAGPGPAAGAAL--PDQSF-LWNVFQRVDKDRSGVISDTELQQALSNGTWT 58
           AA S    P +   P  GA    PD    LW +FQ +D +R G +   +L   L      
Sbjct: 21  AASSSASSPASVGDPCGGAICGGPDHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRR-LGL 79

Query: 59  PFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQN----VFRTYDRDNSGMIDKNE 114
                 ++ I+   D++    ++F EF     Y+ D +     VF++ D+ N G ID  E
Sbjct: 80  HRTEGELQKIVQAGDKDLDGQLDFEEFV---HYLQDHEKKLRLVFKSLDKKNDGRIDAQE 136

Query: 115 LKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151
           + Q+L   G ++S+Q  + +++  D+ G   I ++++
Sbjct: 137 IMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEW 173



 Score = 28.1 bits (61), Expect = 4.8
 Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 7/83 (8%)

Query: 98  VFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIV 157
           +F+T D +  G +  N+L   L   G   ++     +++  D+   GQ+ F++F+     
Sbjct: 53  LFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVH---Y 109

Query: 158 LQ----RLTDIFRRYDTDQDGWI 176
           LQ    +L  +F+  D   DG I
Sbjct: 110 LQDHEKKLRLVFKSLDKKNDGRI 132


>gi|38707981 calpain 12 [Homo sapiens]
          Length = 719

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 4/90 (4%)

Query: 85  FTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRG 144
           F  +W Y+ +WQ +F  +D D SG ++  EL+ AL+  G+ L++Q    L  ++ R  R 
Sbjct: 615 FQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRY-RDSRL 673

Query: 145 QIAFDDFIQGCIVLQRLTDIFRRYDTDQDG 174
           ++ F+ F+  C+    LT IF       DG
Sbjct: 674 RVDFERFV-SCVA--HLTCIFCHCSQHLDG 700


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,477,433
Number of Sequences: 37866
Number of extensions: 320653
Number of successful extensions: 2251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 1754
Number of HSP's gapped (non-prelim): 408
length of query: 191
length of database: 18,247,518
effective HSP length: 96
effective length of query: 95
effective length of database: 14,612,382
effective search space: 1388176290
effective search space used: 1388176290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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