Search of human proteins with 13699836

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]             987   0.0  
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]             967   0.0  
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]             905   0.0  
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]        460   e-129
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]             276   2e-74
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]             267   2e-71
gi|11321565 matrilin 3 precursor [Homo sapiens]                       232   5e-61
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                  176   4e-44
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]              172   5e-43
gi|21359974 vitrin [Homo sapiens]                                     168   1e-41
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...   163   4e-40
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               149   6e-36
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...   147   3e-35
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...   147   3e-35
gi|205277471 cochlin precursor [Homo sapiens]                         145   6e-35
gi|4758022 cochlin precursor [Homo sapiens]                           145   6e-35
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ...   143   3e-34
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   134   1e-31
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                134   3e-31
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ...   132   6e-31
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa...   132   7e-31
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...   131   2e-30
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]      129   8e-30
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                118   1e-26
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         108   1e-23
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        107   3e-23
gi|40068485 von Willebrand factor A domain containing 1 isoform ...   102   6e-22
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            99   9e-21
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        94   2e-19
gi|34452173 integrin alpha X precursor [Homo sapiens]                  88   2e-17

>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
          Length = 499

 Score =  987 bits (2552), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
           MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60

Query: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
           LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120

Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
           MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180

Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCL 240
           LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCL
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCL 240

Query: 241 CPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGT 300
           CPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGT
Sbjct: 241 CPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGT 300

Query: 301 RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA 360
           RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA
Sbjct: 301 RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA 360

Query: 361 RPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL 420
           RPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL
Sbjct: 361 RPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL 420

Query: 421 HVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLN 480
           HVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLN
Sbjct: 421 HVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLN 480

Query: 481 LAQLTARLEDLENQLANQK 499
           LAQLTARLEDLENQLANQK
Sbjct: 481 LAQLTARLEDLENQLANQK 499


>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
          Length = 540

 Score =  967 bits (2500), Expect = 0.0
 Identities = 499/540 (92%), Positives = 499/540 (92%), Gaps = 41/540 (7%)

Query: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
           MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60

Query: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
           LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120

Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
           MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180

Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-------------------------- 214
           LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC                          
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH 240

Query: 215 ---------------VRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 259
                          VRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE
Sbjct: 241 CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 300

Query: 260 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 319
           GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR
Sbjct: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360

Query: 320 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 379
           YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS
Sbjct: 361 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420

Query: 380 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 439
           QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR
Sbjct: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480

Query: 440 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 499
           GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 481 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540


>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
          Length = 581

 Score =  905 bits (2339), Expect = 0.0
 Identities = 482/581 (82%), Positives = 483/581 (83%), Gaps = 82/581 (14%)

Query: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
           MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1   MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60

Query: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
           LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61  LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120

Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
           MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180

Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSY--- 237
           LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC  DLC    HGCE  CV+   SY   
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240

Query: 238 --------------------------------------RCLCPEGRQLQA---------- 249
                                                 RC C EG  LQ           
Sbjct: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300

Query: 250 -------------------------------DGKSCNRCREGHVDLVLLVDGSKSVRPQN 278
                                          DGKSCNRCREGHVDLVLLVDGSKSVRPQN
Sbjct: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360

Query: 279 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 338
           FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER
Sbjct: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420

Query: 339 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 398
           GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY
Sbjct: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480

Query: 399 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 458
           AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC
Sbjct: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540

Query: 459 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 499
           ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581


>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
          Length = 496

 Score =  460 bits (1184), Expect = e-129
 Identities = 253/492 (51%), Positives = 330/492 (67%), Gaps = 20/492 (4%)

Query: 10  LLLLLQPWETQ---LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNV 66
           LLLLLQ   +     Q  G  C T P DLVFV+DSSRSVRP EFE ++ FL  ++  L+V
Sbjct: 14  LLLLLQALCSPGLAPQSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDV 73

Query: 67  GPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFS 126
           GPNATRVG++ Y+S V+  F LRA   +  + +A+R + PL+ GTMTGLAIQ+A+  AF 
Sbjct: 74  GPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFG 133

Query: 127 VAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
            AEG R     + +V ++VTDGRPQD V +V+A+ARA G+E++A+GV   D  +LR +AS
Sbjct: 134 DAEGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVGSVDKATLRQIAS 193

Query: 187 PPLDEHVFLVESFDLIQEFGLQFQSRLC-VRDLCNGVDHGCEFQCVSEGLSYRCLCPEGR 245
            P DEHV  VES+ +I++   +FQ   C V DLC   DH CE  C+S   SY C C EG 
Sbjct: 194 EPQDEHVDYVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCEQVCISSPGSYTCACHEGF 253

Query: 246 QLQADGKSCNRCREG----HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 301
            L +DGK+CN C  G      DLV L+DGSKSVRP+NFELVK+F++QIVD LDVS +  +
Sbjct: 254 TLNSDGKTCNVCSGGGGSSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQ 313

Query: 302 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 361
           VGLVQ+SS VR EFPLGR+ T  ++K AV  + YME+GTMTG AL++++++SF+ + GAR
Sbjct: 314 VGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGAR 373

Query: 362 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELH 421
           P A    +VG+VFTDGRSQD I+  A +AK+ G  M+AVGVG AVE ELREIASEP   H
Sbjct: 374 PGA---QKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEH 430

Query: 422 VSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNL 481
             Y  DF T+  + + L+  IC EE          PC CESLV+FQ +  G L++LT  L
Sbjct: 431 YFYTADFKTINQIGKKLQKKICVEE---------DPCACESLVKFQAKVEGLLQALTRKL 481

Query: 482 AQLTARLEDLEN 493
             ++ RL  LEN
Sbjct: 482 EAVSKRLAILEN 493


>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
          Length = 937

 Score =  276 bits (707), Expect = 2e-74
 Identities = 146/344 (42%), Positives = 202/344 (58%), Gaps = 48/344 (13%)

Query: 200 DLIQEFGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCR 258
           + ++ F L    + C R D+C    HGCE  CV+ G SY C C EG  L  DG+ C +C 
Sbjct: 591 ECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCT 650

Query: 259 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 318
           EG +DLV ++DGSKS+  +NFE+VK+FV  I+D L +SP+  RVGL+Q+S++V TEF L 
Sbjct: 651 EGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLR 710

Query: 319 RYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 378
            + +A ++K+AV  ++YM +G+MTGLAL+HM E SF++ +GARP +  VPR  +VFTDGR
Sbjct: 711 NFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGR 770

Query: 379 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 438
           +QDD+S WA++AK  GI MYAVGVGKA+E EL+EIASEP   H+ YA DF TM  + E L
Sbjct: 771 AQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKL 830

Query: 439 RGSIC--------------------------------PEEGISAGT-------------- 452
           +  IC                                 E+ +   T              
Sbjct: 831 KKGICEALEDSDGRQDSPAGELPKTVQQPTVQHRYLFEEDNLLRSTQKLSHSTKPSGSPL 890

Query: 453 -ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQL 495
            E    C+CE+L+ FQ      +  LT  L ++T R+E LEN+L
Sbjct: 891 EEKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRL 934



 Score =  227 bits (578), Expect = 2e-59
 Identities = 111/235 (47%), Positives = 161/235 (68%)

Query: 20  QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
           Q  L    C     DLVF+IDSSRSV   ++  +++F++ +L+ L++GP+ TRVG++QY 
Sbjct: 43  QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102

Query: 80  SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
           S V++ F L+ F R+ ++ERA++ +  L+ GTMTGLAIQYA+N+AFS AEGARP  E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162

Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
           RV +IVTDGRPQD VAEVAA+AR  GI I+A+GV + D  +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222

Query: 200 DLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 254
             I+     FQ +LC   +C+ ++H C   C++   SY C C +G  L +D  +C
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTC 277



 Score =  169 bits (427), Expect = 7e-42
 Identities = 81/188 (43%), Positives = 126/188 (67%)

Query: 27  RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
           +C  GP+DLVFVID S+S+    FE ++QF+ G++  L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707

Query: 87  PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
            LR F+  +DM++A+  +  + +G+MTGLA+++    +F+  EGARP   RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767

Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
           DGR QD V+E A++A+A GI +YAVGV +A    L+ +AS P ++H+F  E F  + E  
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827

Query: 207 LQFQSRLC 214
            + +  +C
Sbjct: 828 EKLKKGIC 835



 Score =  155 bits (393), Expect = 6e-38
 Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)

Query: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
           C     DLV ++D S+SV   ++  VK F+  I+ FLD+ P+ TRVGL+Q+ S V+ EF 
Sbjct: 51  CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110

Query: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
           L  +   +EV++AV  + ++  GTMTGLA+++ +  +FSEA+GARP   NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170

Query: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
           GR QD ++  AA+A++ GI+++A+GVG+     L+ I SEP E HV    +F  +  L  
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230

Query: 437 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 491
             +  +C     S    L   C    +           +   LN  Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 1/44 (2%)

Query: 212 RLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 254
           + C R D C   DHGCE+ CV+   S+ C CPEG  L++DGK+C
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTC 523



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 207 LQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           L+   + C + D C   DHGCE  CVS   S+ C C EG  L+ DGK+C R
Sbjct: 516 LRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRR 566



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           + L    + CV  D C   +HGCE +CV+   SY C C EG  L  D K+C +
Sbjct: 309 YALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTK 361



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           F L    + C + D C   +HGC+ +CV+   SY C C +G  L  D K+C R
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRR 402



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 6/66 (9%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
           + L    + C R D C   DHGCE  C++   S+ C C EG  +  D K+C+R     VD
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-----VD 486

Query: 264 LVLLVD 269
             LL D
Sbjct: 487 YCLLSD 492



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 202 IQEFGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           ++ F L    + C R + C     GCE +CV+   SY C C  G  L  +GK+C+R
Sbjct: 388 LKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR 443


>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
          Length = 956

 Score =  267 bits (682), Expect = 2e-71
 Identities = 127/245 (51%), Positives = 173/245 (70%), Gaps = 1/245 (0%)

Query: 200 DLIQEFGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCR 258
           + ++ F L    + C R D+C    HGCE  CV+ G SY C C EG  L  DG+ C +C 
Sbjct: 591 ECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCT 650

Query: 259 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 318
           EG +DLV ++DGSKS+  +NFE+VK+FV  I+D L +SP+  RVGL+Q+S++V TEF L 
Sbjct: 651 EGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLR 710

Query: 319 RYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 378
            + +A ++K+AV  ++YM +G+MTGLAL+HM E SF++ +GARP +  VPR  +VFTDGR
Sbjct: 711 NFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGR 770

Query: 379 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 438
           +QDD+S WA++AK  GI MYAVGVGKA+E EL+EIASEP   H+ YA DF TM  + E L
Sbjct: 771 AQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKL 830

Query: 439 RGSIC 443
           +  IC
Sbjct: 831 KKGIC 835



 Score =  227 bits (578), Expect = 2e-59
 Identities = 111/235 (47%), Positives = 161/235 (68%)

Query: 20  QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
           Q  L    C     DLVF+IDSSRSV   ++  +++F++ +L+ L++GP+ TRVG++QY 
Sbjct: 43  QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102

Query: 80  SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
           S V++ F L+ F R+ ++ERA++ +  L+ GTMTGLAIQYA+N+AFS AEGARP  E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162

Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
           RV +IVTDGRPQD VAEVAA+AR  GI I+A+GV + D  +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222

Query: 200 DLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 254
             I+     FQ +LC   +C+ ++H C   C++   SY C C +G  L +D  +C
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTC 277



 Score =  169 bits (427), Expect = 7e-42
 Identities = 81/188 (43%), Positives = 126/188 (67%)

Query: 27  RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
           +C  GP+DLVFVID S+S+    FE ++QF+ G++  L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707

Query: 87  PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
            LR F+  +DM++A+  +  + +G+MTGLA+++    +F+  EGARP   RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767

Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
           DGR QD V+E A++A+A GI +YAVGV +A    L+ +AS P ++H+F  E F  + E  
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827

Query: 207 LQFQSRLC 214
            + +  +C
Sbjct: 828 EKLKKGIC 835



 Score =  155 bits (393), Expect = 6e-38
 Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)

Query: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
           C     DLV ++D S+SV   ++  VK F+  I+ FLD+ P+ TRVGL+Q+ S V+ EF 
Sbjct: 51  CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110

Query: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
           L  +   +EV++AV  + ++  GTMTGLA+++ +  +FSEA+GARP   NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170

Query: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
           GR QD ++  AA+A++ GI+++A+GVG+     L+ I SEP E HV    +F  +  L  
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230

Query: 437 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 491
             +  +C     S    L   C    +           +   LN  Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 1/44 (2%)

Query: 212 RLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 254
           + C R D C   DHGCE+ CV+   S+ C CPEG  L++DGK+C
Sbjct: 480 KTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTC 523



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 207 LQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           L+   + C + D C   DHGCE  CVS   S+ C C EG  L+ DGK+C R
Sbjct: 516 LRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRR 566



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           + L    + CV  D C   +HGCE +CV+   SY C C EG  L  D K+C +
Sbjct: 309 YALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTK 361



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           F L    + C + D C   +HGC+ +CV+   SY C C +G  L  D K+C R
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRR 402



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 6/66 (9%)

Query: 205 FGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
           + L    + C R D C   DHGCE  C++   S+ C C EG  +  D K+C+R     VD
Sbjct: 432 YTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-----VD 486

Query: 264 LVLLVD 269
             LL D
Sbjct: 487 YCLLSD 492



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 1/56 (1%)

Query: 202 IQEFGLQFQSRLCVR-DLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
           ++ F L    + C R + C     GCE +CV+   SY C C  G  L  +GK+C+R
Sbjct: 388 LKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR 443



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 17/43 (39%), Positives = 25/43 (58%)

Query: 453 ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQL 495
           E    C+CE+L+ FQ      +  LT  L ++T R+E LEN+L
Sbjct: 911 EKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRL 953


>gi|11321565 matrilin 3 precursor [Homo sapiens]
          Length = 486

 Score =  232 bits (592), Expect = 5e-61
 Identities = 114/229 (49%), Positives = 163/229 (71%), Gaps = 1/229 (0%)

Query: 28  CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
           C + PLDLVF+IDSSRSVRP EF  ++ F+  ++  L++GP  TRV V+ Y+S V+  F 
Sbjct: 77  CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136

Query: 88  LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
           L+A++ ++ +++A+  + PL+ GTM+GLAIQ AM+ AF+V  GAR P   +P+VA+IVTD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196

Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
           GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++   
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256

Query: 208 QFQSRLCVRDLCNGVDHGCEFQCVSEGL-SYRCLCPEGRQLQADGKSCN 255
           +FQ   C  D C    H C+  C+S+G   + C C +G  L AD K+C+
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCS 305



 Score =  158 bits (400), Expect = 1e-38
 Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)

Query: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
           C+   +DLV ++D S+SVRP  F  VK FV++I+D LD+ P  TRV +V ++S V+ EF 
Sbjct: 77  CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136

Query: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
           L  Y     +KQAV  +  +  GTM+GLA++  ++ +F+   GAR  + N+P+V ++ TD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196

Query: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
           GR QD ++  AARA+  GI +YAVGV +A  A L+ +ASEP E HV Y   +G +  L  
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256

Query: 437 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 480
             + + C  +    GT           E +  CEC     +    +T  AL+   LN
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 2/57 (3%)

Query: 205 FGLQFQSRLC-VRDLCNGVDHGCEFQCVSEG-LSYRCLCPEGRQLQADGKSCNRCRE 259
           + L    + C VRD C    HGC+  CVS+G  SY C C  G  L  D K+C+   E
Sbjct: 379 YTLNADKKTCSVRDKCALGSHGCQHICVSDGAASYHCDCYPGYTLNEDKKTCSATEE 435



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 216 RDLCNGVDHGCEFQCVSEGL-SYRCLCPEGRQLQADGKSCN 255
           +D C    HGC+  CV++   S+ C C EG  L AD K+C+
Sbjct: 349 QDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCS 389


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score =  176 bits (446), Expect = 4e-44
 Identities = 109/414 (26%), Positives = 204/414 (49%), Gaps = 49/414 (11%)

Query: 30  TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
           T   D+  +ID S S +  +F  M+ FL  ++   N+ P+  RVG +QY+      F + 
Sbjct: 432 TEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEIN 491

Query: 90  AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
            +S ++D+ +AI ++  +   T TG A+ + +++   + +  +    +VP   V++T+G 
Sbjct: 492 KYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSL---LQKAKKQRGNKVPCHLVVLTNGM 548

Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
            +D + E A + R   I +YA+G++ A+   LR +A    ++ V+ V  FD +++   Q 
Sbjct: 549 SKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQV 606

Query: 210 QSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 269
              +C  +                                       C+E   D++ LVD
Sbjct: 607 VQEICTEE--------------------------------------ACKEMKADIMFLVD 628

Query: 270 GSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQA 329
            S S+ P+NF  +K F+  +V    + P+  ++G+VQFS   + EF L R+ + +++  A
Sbjct: 629 SSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRFMSQSDISNA 688

Query: 330 VLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAAR 389
           +  + ++ + T+TG AL   V   FS  +GARP   N+ +  ++ TDG +QD +   A  
Sbjct: 689 IDQMAHIGQTTLTGSAL-SFVSQYFSPTKGARP---NIRKFLILITDGEAQDIVKEPAVV 744

Query: 390 AKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSIC 443
            ++EG+++Y+VGV  +   +L EI+  P    V Y  +F  +  + ++L   IC
Sbjct: 745 LRQEGVIIYSVGVFGSNVTQLEEISGRPE--MVFYVENFDILQRIEDDLVFGIC 796



 Score =  163 bits (412), Expect = 4e-40
 Identities = 119/415 (28%), Positives = 204/415 (49%), Gaps = 31/415 (7%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+VF++D S +     F+ ++ FL   +  L++  N  RVG++ YS++ + +  L     
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288

Query: 94  REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
           + ++ + I++L P      TG AI+      FS   G+R   + VP++AV+VT    +D 
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRK-NQGVPQIAVLVTHRDSEDN 347

Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
           V + A   R  G+ I+ +G++ A    L  +AS P +++V  +++F       L   ++ 
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFA-----DLAAHNQT 402

Query: 214 CVRDLCNGVDHGCE-FQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSK 272
            ++ L N + H    F   +E L   C+  E                   D+ LL+DGS 
Sbjct: 403 FLKKLRNQITHTVSVFSERTETLKSGCVDTE-----------------EADIYLLIDGSG 445

Query: 273 SVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLA 332
           S +  +F  +K F++++V   +++P   RVG VQ++     EF + +Y    ++ +A+  
Sbjct: 446 STQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIEN 505

Query: 333 VEYMERGTMTGLALRHMVEHSFSEAQGA-RPRALNVPRVGLVFTDGRSQDDISVWAARAK 391
           +  M   T TG AL      + S  Q A + R   VP   +V T+G S+D I   A R +
Sbjct: 506 IRQMGGNTNTGAAL----NFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLR 561

Query: 392 EEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEE 446
           EE I +YA+G+ +A + +LREIA E  E  V Y  DF  +  +   +   IC EE
Sbjct: 562 EEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQVVQEICTEE 614



 Score =  162 bits (409), Expect = 9e-40
 Identities = 118/383 (30%), Positives = 189/383 (49%), Gaps = 44/383 (11%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
            LD+VFVIDSS S+   E+  M+ F++GL++  +VG N  R G ++Y+   + +F L  F 
Sbjct: 808  LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFG 867

Query: 93   RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
             + ++   +++   +   T T  A+ ++ ++ F+ A G+R   + VP+V +++TDG   D
Sbjct: 868  TKLEVISVLQNDQAMGGSTYTAEALGFSDHM-FTEARGSRL-NKGVPQVLIVITDGESHD 925

Query: 153  --RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ 210
              ++   A   R +GI + AVG+  A+   L AMA     +  F VE+F      GL+  
Sbjct: 926  ADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGS--SDKYFFVETFG-----GLKGI 978

Query: 211  SRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDG 270
                   +CN     CE                                  VDLV L+DG
Sbjct: 979  FSDVTASVCNSSKVDCEID-------------------------------KVDLVFLMDG 1007

Query: 271  SKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAV 330
            S S++P +F+ +K F+  +V   DVS    R+G  QFS     EFPLG +    E+   +
Sbjct: 1008 STSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTFIGEKEISFQI 1067

Query: 331  LAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
              ++ +   T  G ALR  VEH F    G+R      P+V LV TDG+SQD+++  A   
Sbjct: 1068 ENIKQIFGNTHIGAALRE-VEHYFRPDMGSRINT-GTPQVLLVLTDGQSQDEVAQAAEAL 1125

Query: 391  KEEGIVMYAVGVGKAVEAELREI 413
            +  GI +Y+VG+G   + +L +I
Sbjct: 1126 RHRGIDIYSVGIGDVDDQQLIQI 1148



 Score =  159 bits (403), Expect = 4e-39
 Identities = 118/422 (27%), Positives = 200/422 (47%), Gaps = 48/422 (11%)

Query: 24  TGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQ 83
           T   C     D++F++DSS S+ P  F  M+ F+  L+    +GP+  ++GV+Q+S   +
Sbjct: 612 TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINK 671

Query: 84  SVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
             F L  F  + D+  AI  +  + Q T+TG A+ + ++  FS  +GARP    + +  +
Sbjct: 672 EEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSF-VSQYFSPTKGARP---NIRKFLI 727

Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
           ++TDG  QD V E A   R  G+ IY+VGV  ++V  L  ++  P  E VF VE+FD++Q
Sbjct: 728 LITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMVFYVENFDILQ 785

Query: 204 EFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
                                      + + L +    P         + C R     +D
Sbjct: 786 R--------------------------IEDDLVFGICSPR--------EECKRIEV--LD 809

Query: 264 LVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTA 323
           +V ++D S S+    + ++K F+  +V   DV     R G ++++      F L  +GT 
Sbjct: 810 VVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTK 869

Query: 324 AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ--D 381
            EV   +   + M   T T  AL    +H F+EA+G+R     VP+V +V TDG S   D
Sbjct: 870 LEVISVLQNDQAMGGSTYTAEAL-GFSDHMFTEARGSRLNK-GVPQVLIVITDGESHDAD 927

Query: 382 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 441
            ++  A   +++GI++ AVG+  A   EL  +A    +    +   FG +  +  ++  S
Sbjct: 928 KLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYF--FVETFGGLKGIFSDVTAS 985

Query: 442 IC 443
           +C
Sbjct: 986 VC 987



 Score =  132 bits (333), Expect = 6e-31
 Identities = 111/432 (25%), Positives = 198/432 (45%), Gaps = 36/432 (8%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+VF++DSS  +    F  ++ F+  ++  L +  +  RV + QYS ++ S F L  F  
Sbjct: 27  DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86

Query: 94  REDMERAIRDLVPLAQGTM-TGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
           R  M   +R       G++  G A+Q A    FS     R  +++ P + V++     +D
Sbjct: 87  RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGR-DKKQFPPILVVLASSESED 145

Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSR 212
            V E +   R  G++I +VGVQ+A   +L+AMA+     ++  V    +  +        
Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQ-------- 197

Query: 213 LCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSK 272
                    + H      + + + Y+    EG       ++C        D+V L+D S 
Sbjct: 198 --------NMTH-----IIKDVIKYK----EGAVDDIFVEACQ--GPSMADVVFLLDMSI 238

Query: 273 SVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLA 332
           +   +NF+ +K F+ + V  LD+     RVGLV +S+  +    L      +EV Q +  
Sbjct: 239 NGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQN 298

Query: 333 VEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKE 392
           +        TG A++ + +  FS   G+R +   VP++ ++ T   S+D+++  A   + 
Sbjct: 299 LSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDNVTKAAVNLRR 357

Query: 393 EGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMT----HLLENLRGSICPEEGI 448
           EG+ ++ +G+  A + +L +IAS PAE +VS    F  +       L+ LR  I     +
Sbjct: 358 EGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKLRNQITHTVSV 417

Query: 449 -SAGTE-LRSPC 458
            S  TE L+S C
Sbjct: 418 FSERTETLKSGC 429



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 4/187 (2%)

Query: 28   CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
            C    +DLVF++D S S++P +F+ M++FL  +++  +V  N  R+G  Q+S      FP
Sbjct: 994  CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053

Query: 88   LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
            L  F   +++   I ++  +   T  G A++   +  F    G+R      P+V +++TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHY-FRPDMGSR-INTGTPQVLLVLTD 1111

Query: 148  GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
            G+ QD VA+ A   R RGI+IY+VG+   DV   + +      E    V +FD +++   
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGI--GDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169

Query: 208  QFQSRLC 214
            +    +C
Sbjct: 1170 RIVRNIC 1176



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 93/430 (21%), Positives = 177/430 (41%), Gaps = 70/430 (16%)

Query: 26   PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG----VIQYSSQ 81
            P C   P +LVF +D SR V   EFE M++ +  L+R + V  N+  VG    ++ Y+S 
Sbjct: 1749 PECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSH 1808

Query: 82   VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT---GLAIQYAMNVAFSVAEGARPPEERV 138
             + +       ++  + R I + +P  + + +   G A+++     F        P    
Sbjct: 1809 ARHLVRFSDAYKKSQLLREI-ETIPYERSSASREIGRAMRFISRNVFK----RTLPGAHT 1863

Query: 139  PRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVES 198
             ++A   + G+  D  +   A      +EI  V +  ++V S+R           F ++ 
Sbjct: 1864 RKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVR---------RAFAIDD 1914

Query: 199  FDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCR 258
                Q                  V  G ++    E L     C +  +  A   SC++ R
Sbjct: 1915 TGTFQVI---------------VVPSGADYIPALERLQRCTFCYDVCKPDA---SCDQAR 1956

Query: 259  ----EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRVGLVQFS 308
                + ++D   L+D S+++    FE ++ F+  ++D  +++PE      G RV L+  +
Sbjct: 1957 PPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHA 2016

Query: 309  ----------SRVRTEFPLGRYGTAAEVKQAV-LAVEYMERGTMTGLALRHMVEHSFSEA 357
                      S VR EF L  Y +   +K+ V  +V+ +      G AL+  +++ F   
Sbjct: 2017 PPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVFLST 2076

Query: 358  QGARPRALNVPRVGLVFTDGRSQ----DDISVWAARAKEEGIVMYAVGVGKA-VEAELRE 412
               R       +V  V + G +     + +   + RAK +G  ++   +G    + EL +
Sbjct: 2077 PNLRRN-----KVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELED 2131

Query: 413  IASEPAELHV 422
            +AS P + H+
Sbjct: 2132 LASHPLDHHL 2141



 Score = 65.9 bits (159), Expect = 8e-11
 Identities = 43/183 (23%), Positives = 87/183 (47%), Gaps = 6/183 (3%)

Query: 261 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 320
           + D+V LVD S  +  ++F  VK F+ +++  L +  +  RV L Q+S ++ +EF L  +
Sbjct: 25  YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTF 84

Query: 321 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 379
            G +  +        ++      G AL+      FS     R +    P + +V     S
Sbjct: 85  KGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKK-QFPPILVVLASSES 143

Query: 380 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG----TMTHLL 435
           +D++   +   +++G+ + +VGV KA E  L+ +A+     ++    D       MTH++
Sbjct: 144 EDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHII 203

Query: 436 ENL 438
           +++
Sbjct: 204 KDV 206


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score =  172 bits (437), Expect = 5e-43
 Identities = 111/387 (28%), Positives = 198/387 (51%), Gaps = 47/387 (12%)

Query: 30  TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
           T   D+ F+ID S S++  +FE +++F++ +    ++GP+  RVGV+QYS   +  F + 
Sbjct: 438 TKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYIT 497

Query: 90  AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
            +S   D+ +AI ++  L  GT TG A+ Y + +   +  G +    +VP   +++TDG 
Sbjct: 498 DYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQI---IKNGMKDRMSKVPCYLIVLTDGM 554

Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
             DRV E A + RA  I ++AVG+  A+   L+ +A    +E V   ++FD ++      
Sbjct: 555 STDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGK--EERVSFGQNFDALKSI---- 608

Query: 210 QSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 269
                VR++C   + GCE                               +   D++ LVD
Sbjct: 609 -KNEVVREIC--AEKGCE-------------------------------DMKADIMFLVD 634

Query: 270 GSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQA 329
            S S+  +NF  +K F+  ++  + +  + T++G+VQFS + + EF L RY T  E+  A
Sbjct: 635 SSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQLNRYFTQQEISDA 694

Query: 330 VLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAAR 389
           +  +  +  GT+TG AL + V   F+ ++GAR   L   +  ++ TDG +QDD+   A  
Sbjct: 695 IDRMSLINEGTLTGKAL-NFVGQYFTHSKGAR---LGAKKFLILITDGVAQDDVRDPARI 750

Query: 390 AKEEGIVMYAVGVGKAVEAELREIASE 416
            + + + +++VGV  A  ++L EI+ +
Sbjct: 751 LRGKDVTIFSVGVYNANRSQLEEISGD 777



 Score =  162 bits (410), Expect = 7e-40
 Identities = 110/414 (26%), Positives = 207/414 (50%), Gaps = 28/414 (6%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           DLVF++D S          ++ FL  +   ++V  N  R+G++ YS+  +++  L++ + 
Sbjct: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294

Query: 94  REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
           + + ++ I++L      + TG AI       FS + G+R  +  VP++AV+VT     D 
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQG-VPQIAVLVTHRPSDDE 353

Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
           V + A   R   + ++A+ +Q A+   L  + S P ++ +  ++S+  ++ +  +F  +L
Sbjct: 354 VHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKL 413

Query: 214 CVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKS 273
                        + +  S+  +Y        Q   D   C   +E   D+  L+DGS S
Sbjct: 414 -------------QNEIWSQISTY------AEQRNLDKTGCVDTKEA--DIHFLIDGSSS 452

Query: 274 VRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAV 333
           ++ + FE +KRF+ ++ +   + P+  RVG+VQ+S     EF +  Y    ++++A+  +
Sbjct: 453 IQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNI 512

Query: 334 EYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEE 393
           + +  GT TG AL ++++       G + R   VP   +V TDG S D +   A R + E
Sbjct: 513 KQLTGGTYTGKALDYILQ---IIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAE 569

Query: 394 GIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEG 447
            I ++AVG+G A + EL+EIA +  E  VS+  +F  +  +   +   IC E+G
Sbjct: 570 QITVHAVGIGAANKIELQEIAGK--EERVSFGQNFDALKSIKNEVVREICAEKG 621



 Score =  127 bits (319), Expect = 2e-29
 Identities = 104/420 (24%), Positives = 196/420 (46%), Gaps = 49/420 (11%)

Query: 28  CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
           C     D++F++DSS S+    F  M+ F+  LL  + +G + T++GV+Q+S + +  F 
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681

Query: 88  LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
           L  +  ++++  AI  +  + +GT+TG A+ + +   F+ ++GAR   +   +  +++TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VGQYFTHSKGARLGAK---KFLILITD 737

Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
           G  QD V + A   R + + I++VGV  A+   L  ++       VF VE+FD ++    
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD--SSLVFHVENFDHLKALER 795

Query: 208 QFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLL 267
           +   R+C         H C+                              R   +D+V +
Sbjct: 796 KLIFRVCAL-------HDCK------------------------------RITLLDVVFV 818

Query: 268 VDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVK 327
           +D S S++ Q  + +      +V   DV  +  + G +++S +    F L  Y   + + 
Sbjct: 819 LDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAII 878

Query: 328 QAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS--QDDISV 385
           + +         T T  AL+H     F+E  G+R +  NV ++ +V TDG S   D ++ 
Sbjct: 879 ENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQ-NVKQMLIVITDGESHDHDQLND 936

Query: 386 WAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPE 445
            A   + +GI ++AVGVGKA + EL  +A    + +  Y  +F  +  +   ++  +C E
Sbjct: 937 TALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQERMCTE 994



 Score =  121 bits (304), Expect = 1e-27
 Identities = 115/443 (25%), Positives = 196/443 (44%), Gaps = 39/443 (8%)

Query: 9   VLLLLLQPWETQL--QLTGPRCHTGPL--DLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
           +++ +L  W   L  Q  GP    GP+  D+VF++DSS  + P  F  ++ F+  ++  L
Sbjct: 5   LIIFVLIIWTETLADQSPGP----GPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60

Query: 65  NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTM-TGLAIQYAMNV 123
            +  N  RV + QYS +  S F L  F  R  M   ++       G++  G A+Q A   
Sbjct: 61  PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120

Query: 124 AFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRA 183
            FS     R   ++ P + V++     +D V E +   +  G++I +VGVQ+A   +L+A
Sbjct: 121 YFSAPINGR-DRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKA 179

Query: 184 MASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPE 243
           MA+                  F L+      +RDL     +    Q + +   Y+    +
Sbjct: 180 MATSHF--------------HFNLR-----TIRDLSTFSQN--MTQIIKDVTKYKEGAVD 218

Query: 244 GRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVG 303
                    SC   ++   DLV LVD S      N   ++ F+  I   +DV     R+G
Sbjct: 219 ADMQVHFPISCQ--KDSLADLVFLVDESLGT-GGNLRHLQTFLENITSSMDVKENCMRLG 275

Query: 304 LVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 363
           L+ +S+  +T   L    T +E +Q +  +      + TG A+  M    FSE+ G+R R
Sbjct: 276 LMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSR-R 334

Query: 364 ALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVS 423
           A  VP++ ++ T   S D++   A   + E + ++A+ +  A   +L EI S P E  +S
Sbjct: 335 AQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTIS 394

Query: 424 YAPDFGTM----THLLENLRGSI 442
               +  +    T  L+ L+  I
Sbjct: 395 TLKSYADLETYSTKFLKKLQNEI 417



 Score =  112 bits (279), Expect = 1e-24
 Identities = 95/390 (24%), Positives = 171/390 (43%), Gaps = 44/390 (11%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
            LD+VFV+D S S++    + M    + L++  +VG +  + G ++YS Q   +F L  +S
Sbjct: 813  LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872

Query: 93   RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG--RP 150
             R  +   +R        T T  A+++A N  F+   G+R  ++ V ++ +++TDG    
Sbjct: 873  NRSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSR-IKQNVKQMLIVITDGESHD 930

Query: 151  QDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ 210
             D++ + A + R +GI I+AVGV +A+   L  MA      +   V++FD +++     Q
Sbjct: 931  HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988

Query: 211  SRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDG 270
             R+C                           PE   LQ              D++ L DG
Sbjct: 989  ERMCTE------------------------APEVCHLQ------------EADVIFLCDG 1012

Query: 271  SKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAV 330
            S  V   +F  +  F++ ++D  D+  +  ++G+ QF S  ++   L    T  + K  +
Sbjct: 1013 SDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQI 1072

Query: 331  LAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
              V           AL+  V + F+   G R R   VP+  +V T G  + D++      
Sbjct: 1073 QNVSKSGGFPRIDFALK-KVSNMFNLHAGGR-RNAGVPQTLVVITSGDPRYDVADAVKTL 1130

Query: 391  KEEGIVMYAVGVGKAVEAELREIASEPAEL 420
            K+ GI +  +G+G   +  L  I     ++
Sbjct: 1131 KDLGICVLVLGIGDVYKEHLLPITGNSEKI 1160



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 60/246 (24%), Positives = 112/246 (45%), Gaps = 16/246 (6%)

Query: 261 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 320
           + D+V LVD S  + P++F  VK F+N++++ L +     RV L Q+S    +EF L  +
Sbjct: 28  YADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTF 87

Query: 321 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 379
            G +  +       +++      G AL+      FS     R R    P + +V     S
Sbjct: 88  KGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRK-QFPPILVVLASAES 146

Query: 380 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGT----MTHLL 435
           +D++   +   +++G+ + +VGV KA E  L+ +A+     ++    D  T    MT ++
Sbjct: 147 EDEVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQII 206

Query: 436 ENLRGSICPEEGISAGTELRSPCECES--------LVEFQGRTLGALESLTLNLAQLTAR 487
           +++  +   E  + A  ++  P  C+         LV+    T G L  L   L  +T+ 
Sbjct: 207 KDV--TKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSS 264

Query: 488 LEDLEN 493
           ++  EN
Sbjct: 265 MDVKEN 270



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 95/426 (22%), Positives = 171/426 (40%), Gaps = 70/426 (16%)

Query: 27   RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN----ATRVGVIQYSSQV 82
            +C   P +LVF +D+S  V    F   R  +  ++  LN+  N      RV ++ Y+S  
Sbjct: 1751 KCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGT 1810

Query: 83   QSVFPLRAFSRREDMERAIRDLV--PLAQGTMTGLAIQYAM-NVAFSVAEGARPPEERVP 139
              +     ++R++ + + +  +      +    G A+++   NV      GA      V 
Sbjct: 1811 SYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGAN-----VR 1865

Query: 140  RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPL---DEHVFLV 196
            RVAV  ++G+   R + + A      ++I                 SP +   DE VFL 
Sbjct: 1866 RVAVFFSNGQTASRSSIITATMEFSALDI-----------------SPTVFAFDERVFL- 1907

Query: 197  ESFDLIQEFGLQFQSRLCVRDLC-NGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCN 255
                  + FG        V  +  NG +         E L    LC +     A  +   
Sbjct: 1908 ------EAFGFDNTGTFQVIPVPPNGENQ------TLERLRRCALCYDKCFPNACIREAF 1955

Query: 256  RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD------VSPEGTRVGLVQFS- 308
               + ++D+V L+D S+++    F+ VK  V+ ++D  +      +S  G R+ L+ +S 
Sbjct: 1956 LPEDSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSP 2015

Query: 309  --------SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMT-GLALRHMVEHSFSEAQG 359
                      V+TEF    Y     +K  +        G  T G AL    E+ F E   
Sbjct: 2016 WESSRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPY 2075

Query: 360  ARPRALNVPRVGLVFTDGRS---QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASE 416
             R       +V  V + G +   ++ + + A RAK +G V++ + +G   + ++ E+AS 
Sbjct: 2076 LRKH-----KVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASY 2130

Query: 417  PAELHV 422
            P + H+
Sbjct: 2131 PLDQHL 2136



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 43/192 (22%), Positives = 86/192 (44%), Gaps = 7/192 (3%)

Query: 28   CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
            CH    D++F+ D S  V   +F TM  FL  L+   ++     ++G+ Q+ S  QS+  
Sbjct: 999  CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIE 1058

Query: 88   LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
            L+    +   +  I+++           A++   N+ F++  G R     VP+  V++T 
Sbjct: 1059 LKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNM-FNLHAGGR-RNAGVPQTLVVITS 1116

Query: 148  GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
            G P+  VA+     +  GI +  +G+   DV     +      E +   + FD ++   +
Sbjct: 1117 GDPRYDVADAVKTLKDLGICVLVLGI--GDVYKEHLLPITGNSEKIITFQDFDKLKNVDV 1174

Query: 208  QFQSRLCVRDLC 219
            +   +  +R++C
Sbjct: 1175 K---KRIIREIC 1183



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 42/182 (23%), Positives = 82/182 (45%), Gaps = 18/182 (9%)

Query: 258  REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRVGLVQFS--- 308
            +E ++D+  L+D S+ V    F+ VK F+  ++D+  ++P       G RV ++ +S   
Sbjct: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345

Query: 309  -------SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 361
                     V  EF L  Y +  ++K  +   + +      G AL+  +++ F      R
Sbjct: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405

Query: 362  PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVG-KAVEAELREIASEPAEL 420
               + +  +    T+   +D +   + RAK +G  ++    G K  + EL E+AS P + 
Sbjct: 2406 KNKV-IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDH 2464

Query: 421  HV 422
            H+
Sbjct: 2465 HL 2466



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 28/183 (15%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN------ATRVGVIQYS------- 79
            +D+ F+ID+S+ V   EF+ ++ F+  +L   ++ P         RV V+ YS       
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349

Query: 80   ---SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEE 136
                 V   F L  ++    M+  ++D   L      G A+Q+ ++  F        P  
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVF-----VGTPNL 2404

Query: 137  RVPRVAVIVTDGR----PQDRVAEVAAQARARG--IEIYAVGVQRADVGSLRAMASPPLD 190
            R  +V  +++ G      +D +  V+ +A+ +G  I +++ G +  D   L  +AS PLD
Sbjct: 2405 RKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHND-KELEELASHPLD 2463

Query: 191  EHV 193
             H+
Sbjct: 2464 HHL 2466


>gi|21359974 vitrin [Homo sapiens]
          Length = 693

 Score =  168 bits (425), Expect = 1e-41
 Identities = 115/429 (26%), Positives = 190/429 (44%), Gaps = 44/429 (10%)

Query: 21  LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
           + L  P C    +DL F+ID S S+    F   +Q L  + + L++GP    +GV+QY  
Sbjct: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354

Query: 81  QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
              + F L+  +   D++ AI  +      +  G AI +     FS A G R      P 
Sbjct: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411

Query: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFL----V 196
           V V++ DG P D+V E +  AR  GI I+ + ++ A     + +  P             
Sbjct: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGF 471

Query: 197 ESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
            S  +   FGL    +  V+ +C+                             D  +C++
Sbjct: 472 YSLHVQSWFGLHKTLQPLVKRVCD----------------------------TDRLACSK 503

Query: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
                 D+  ++DGS SV   NF  V +FV  +    ++S   TR+G VQ++   R EF 
Sbjct: 504 TCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFG 563

Query: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
             +Y +  ++  A+  V Y   GT TG A+   +E  F +++       N  ++ ++ TD
Sbjct: 564 FDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP------NKRKLMILITD 617

Query: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
           GRS DD+ + A  A  +G++ YA+GV  A + EL  IA+ PA  H  +  +F  +   + 
Sbjct: 618 GRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVP 677

Query: 437 NLRGSICPE 445
            +  +IC E
Sbjct: 678 RIIQNICTE 686


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
           sapiens]
          Length = 3177

 Score =  163 bits (412), Expect = 4e-40
 Identities = 115/407 (28%), Positives = 206/407 (50%), Gaps = 32/407 (7%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D++F++DSS ++    F+ +R+FL  +++ L VG N     ++Q++    + F L  +  
Sbjct: 39  DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98

Query: 94  REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
           ++++   I ++  +     TG  ++Y M    + A G+R  +  VP+V V++TDG  +D 
Sbjct: 99  KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDG-VPQVIVVLTDGHSKDG 157

Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
           +A  +A+ ++  + ++A+GV+ AD G+L+ +AS PL+ H+F +E+F  + +         
Sbjct: 158 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDI-------- 209

Query: 214 CVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKS 273
                      G    CV   +S     PE        K      +   D++ L+DGS +
Sbjct: 210 ----------VGNLVSCVHSSVS-----PERAGDTETLKDIT--AQDSADIIFLIDGSNN 252

Query: 274 VRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAV 333
               NF ++  F+  +++ L +  +  RVG+VQFS   RT F L  Y T A+V  AV A+
Sbjct: 253 TGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKAL 312

Query: 334 EYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAK 391
            +   G +   GLAL  +VE+ F+ A G+R     VP+V ++ + G S D+I       K
Sbjct: 313 GF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSSDEIRYGVVALK 370

Query: 392 EEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 438
           +  +  + +G   A  AEL+ IA++  +  V   P+F +   L E L
Sbjct: 371 QASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 415



 Score =  147 bits (370), Expect = 3e-35
 Identities = 135/452 (29%), Positives = 213/452 (47%), Gaps = 43/452 (9%)

Query: 26   PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
            P   +   D+VF+IDSS  VRP  F  +R F+  ++R LN+GP+  RVGV+Q+S+ V   
Sbjct: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1487

Query: 86   FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
            F L+ +  +  +  AIR L  L  G+   TG A+++     F  + G+R  E+ VP+  V
Sbjct: 1488 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1545

Query: 144  IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
            +V  G+ QD V+  A   R+ GI    VG +  D   L+ + + P    VF V  F    
Sbjct: 1546 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREF---- 1599

Query: 204  EFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
                        R+L N  +        S G S     P G     D    +R  +   D
Sbjct: 1600 ------------RELPNIEERIMN----SFGPSAATPAPPG----VDTPPPSRPEKKKAD 1639

Query: 264  LVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTA 323
            +V L+DGS + R  +F+ V RFV++IVD +    +  +VGLVQ++S    EF L  + T 
Sbjct: 1640 IVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTK 1699

Query: 324  AEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             ++  A+  V Y   R   T + L H+  + F    G+R     VP++  V T G+S +D
Sbjct: 1700 RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVED 1758

Query: 383  ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG 440
                +    + G+ ++AVGV      E+ +IAS  A    V    +   ++  +LE L  
Sbjct: 1759 AQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHD 1818

Query: 441  ----SICPEEGISAGTELRSPCECESLVEFQG 468
                ++CP  G+   T+    C  + ++ F G
Sbjct: 1819 AMHETLCP--GV---TDAAKACNLDVILGFDG 1845



 Score =  137 bits (345), Expect = 2e-32
 Identities = 120/429 (27%), Positives = 204/429 (47%), Gaps = 32/429 (7%)

Query: 31   GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
            G  D+VF+ID S+S  P EF+ +R  +  L+  L+VG + TRV VIQ+S   +  F L A
Sbjct: 1230 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288

Query: 91   FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
             S +++++ A++ L P   +    G A++Y     F    G+R  EE VP+  V+++ G+
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1347

Query: 150  PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
              D V + A + +  G+  + +  + AD   L  ++  P  E+VF V +F  +     + 
Sbjct: 1348 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 1404

Query: 210  QSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 269
             + +               + + + L+     P   +  A             D+V L+D
Sbjct: 1405 LTPITT----------LTSEQIQKLLASTRYPPPAVESDA------------ADIVFLID 1442

Query: 270  GSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQA 329
             S+ VRP  F  ++ FV++IV  L++ P   RVG+VQFS+ V  EF L  Y + A V  A
Sbjct: 1443 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1502

Query: 330  VLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAA 388
            +  +       + TG AL  +  + F ++ G+R     VP+  ++   G+SQDD+S +A 
Sbjct: 1503 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQDDVSRFAQ 1561

Query: 389  RAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGI 448
              +  GIV   VG       EL+ I ++P    V    +F  + ++ E +  S  P    
Sbjct: 1562 VIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREFRELPNIEERIMNSFGPSAAT 1619

Query: 449  SAGTELRSP 457
             A   + +P
Sbjct: 1620 PAPPGVDTP 1628



 Score =  132 bits (333), Expect = 6e-31
 Identities = 116/415 (27%), Positives = 200/415 (48%), Gaps = 40/415 (9%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D++F+ID S +     F  +  FL+ LL  L +G    RVGV+Q+S + +++F L  +S 
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301

Query: 94  REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           +  +  A++ L   A G +   GLA+ + +   F+ A G+R  EE VP+V V+++ G   
Sbjct: 302 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSRV-EEGVPQVLVLISAGPSS 359

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           D +       +   +  + +G Q A    L+ +A+   D  VF V  F   + FG   Q 
Sbjct: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF---RSFG-DLQE 413

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
           +L    +               G++ R +  +   +       N+      D+V LVDGS
Sbjct: 414 KLLPYIV---------------GVAQRHIVLKPPTIVTQVIEVNKR-----DIVFLVDGS 453

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            ++   NF  ++ F+ +++  L++  +  +V + Q++  VR EF    + T  EV  AV 
Sbjct: 454 SALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVR 513

Query: 332 AVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            ++ ++   + TG AL  +  + F+ + G R  A  +P++ ++ T G+S D+IS  A   
Sbjct: 514 KMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLDEISQPAQEL 572

Query: 391 KEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLLENLR 439
           K   I+ +A+G   A +AEL EIA +      PAE     AP  G +  LL  LR
Sbjct: 573 KRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLLAPLR 625



 Score =  132 bits (331), Expect = 1e-30
 Identities = 116/434 (26%), Positives = 201/434 (46%), Gaps = 41/434 (9%)

Query: 13   LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
            LL P  T   L+G P  H+   D++F++D S +V    F  +R F+M L+  L++G +  
Sbjct: 620  LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 676

Query: 72   RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
            RVG++Q+S    + F L  +  + D+   +R L +    G  TG A+ Y     F+ A G
Sbjct: 677  RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 736

Query: 131  ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
            +R   E VP++ +++T G+ +D   + A      GI  + VG  +A+   L  +A  P  
Sbjct: 737  SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 793

Query: 191  EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
              V+L++ F  +     Q      ++ L   V  G E   +++        PE ++    
Sbjct: 794  SLVYLMDDFSSLPALPQQL-----IQPLTTYVSGGVEEVPLAQ--------PESKR---- 836

Query: 251  GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSR 310
                        D++ L DGS ++  Q F +V+ F+ +I+D L+V PEGTR+ + Q+S  
Sbjct: 837  ------------DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDD 883

Query: 311  VRTEFPLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 369
            V+ E     + +  E+   V  ++    +    G AL +   + F ++ G+R     V +
Sbjct: 884  VKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQ 942

Query: 370  VGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDF 428
              ++   GRS D +   A+  K+ G+V +      A  AEL +I   PA  L     P  
Sbjct: 943  FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKI 1002

Query: 429  GTMTHLLENLRGSI 442
            G +   + NL  S+
Sbjct: 1003 GDLHPQIVNLLKSV 1016



 Score =  124 bits (312), Expect = 2e-28
 Identities = 103/390 (26%), Positives = 187/390 (47%), Gaps = 31/390 (7%)

Query: 30   TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
            +G  D+VF++D S  VR   F  +++F+  ++  L+VG +  RV V+QYS + +  F L 
Sbjct: 1025 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 1083

Query: 90   AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
            ++  ++D+  A+R L  L   T  TG A+++ +      + G+R   E VP++ +++T  
Sbjct: 1084 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 1142

Query: 149  RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
            R  D V   +   +  G     +G+  AD+  ++ ++  P  +    + +F  +      
Sbjct: 1143 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQV 1200

Query: 209  FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
               R+               Q   E LS   L P  + L + G        G  D+V L+
Sbjct: 1201 ISERVT--------------QLTREELSR--LQPVLQPLPSPGVG------GKRDVVFLI 1238

Query: 269  DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
            DGS+S  P+ F+ V+  + ++VD+LDV  + TRV ++QFS   + EF L  + +  EV+ 
Sbjct: 1239 DGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 1297

Query: 329  AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
            AV  +     R    G AL ++  + F    G+R     VP+  ++ + G+S D++   A
Sbjct: 1298 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGKSDDEVDDPA 1356

Query: 388  ARAKEEGIVMYAVGVGKAVEAELREIASEP 417
               K+ G+  + +    A + EL +I+  P
Sbjct: 1357 VELKQFGVAPFTI-ARNADQEELVKISLSP 1385



 Score =  117 bits (292), Expect = 3e-26
 Identities = 111/398 (27%), Positives = 173/398 (43%), Gaps = 53/398 (13%)

Query: 34   DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
            D++F+ D S ++   +F  +R FL  ++  LNV P  TR+ V QYS   +V+S F     
Sbjct: 837  DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 894

Query: 92   SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
            S+ E +    R  +   +    G A+ YA    F  + G+R  E+ V +  V++  GR  
Sbjct: 895  SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRI-EDGVLQFLVLLVAGRSS 953

Query: 152  DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
            DRV   A+  +  G+  +    + AD   L  +   P    +   ES   I +   Q   
Sbjct: 954  DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQ--- 1008

Query: 212  RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
               + +L   V +G                                  G  D+V L+DGS
Sbjct: 1009 ---IVNLLKSVHNGAPAPV----------------------------SGEKDVVFLLDGS 1037

Query: 272  KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            + VR   F L+K FV ++V+ LDV  +  RV +VQ+S R R EF L  Y    +V  AV 
Sbjct: 1038 EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 1096

Query: 332  AVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
             +  +   T  TG AL  ++ +    + G+R     VP++ +V T  RS DD+   +   
Sbjct: 1097 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADRSGDDVRNPSVVV 1155

Query: 391  KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 428
            K  G V   +G+G A   E++ I         S+ PDF
Sbjct: 1156 KRGGAVPIGIGIGNADITEMQTI---------SFIPDF 1184



 Score =  103 bits (258), Expect = 3e-22
 Identities = 66/205 (32%), Positives = 109/205 (53%), Gaps = 10/205 (4%)

Query: 245 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 304
           +Q QAD K+         D++ LVD S ++  ++F+LV+ F+  +V  L V        L
Sbjct: 26  QQQQADVKN-----GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFAL 80

Query: 305 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 364
           VQF+    TEF L  Y T  EV   +  + Y+     TG  L ++++   ++A G+R   
Sbjct: 81  VQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSR-AG 139

Query: 365 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 424
             VP+V +V TDG S+D +++ +A  K   + ++A+GV  A E  L+EIASEP  +H+  
Sbjct: 140 DGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFN 199

Query: 425 APDFGTMTHLLENL----RGSICPE 445
             +F ++  ++ NL      S+ PE
Sbjct: 200 LENFTSLHDIVGNLVSCVHSSVSPE 224



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 98/435 (22%), Positives = 178/435 (40%), Gaps = 72/435 (16%)

Query: 25   GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
            GP  C   P +L F +D+S  V    F  MR  ++ ++  L +     P   RV V+ Y+
Sbjct: 2392 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 2451

Query: 80   SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
            ++V +        R+  +   I++L    Q  +T    Q ++  A S    AR   +RV 
Sbjct: 2452 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRVR 2503

Query: 140  ------RVAVIV--TDGRPQDRVAEVAAQARARGIE-IYAVGVQRADVGSLRAMASPPLD 190
                  +VAV    T  R   ++ E   +    GI  ++    +   + +   + +  + 
Sbjct: 2504 NGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVG 2563

Query: 191  EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
              + L    DL           +C+ D+CN +D  C F       S+R   P  R  +A 
Sbjct: 2564 HALVLPAGRDLTDFLENVLTCHVCL-DICN-IDPSCGFG------SWR---PSFRDRRAA 2612

Query: 251  GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGL 304
            G   +      +D+  ++D +++     F  +K+++  +V  LD+SP+        RV +
Sbjct: 2613 GSDVD------IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAV 2666

Query: 305  VQFSSR----------VRTEFPLGRYGTAAEVKQAVLAVEYMERG-------TMTGLALR 347
            VQ +            V+ EF L  YG+  ++      V+++ RG          G A+ 
Sbjct: 2667 VQHAPSESVDNASMPPVKVEFSLTDYGSKEKL------VDFLSRGMTQLQGTRALGSAIE 2720

Query: 348  HMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAV 406
            + +E+ F  A    PR L +  + L       Q ++      +AK +G     +G+G+ V
Sbjct: 2721 YTIENVFESA--PNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKV 2778

Query: 407  E-AELREIASEPAEL 420
               E+   ASEP ++
Sbjct: 2779 NIKEVYTFASEPNDV 2793



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
            +D+ F++DS+ +   F+F  M++++  L+R L++ P+        RV V+Q++       
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677

Query: 82   -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
                 V+  F L  +  +E +   +   +   QGT   G AI+Y +   F  A     P 
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2732

Query: 136  ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
             R  ++ V++  G  P+ ++ E   V  QA+ +G     +G+ ++ ++  +   AS P D
Sbjct: 2733 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792

Query: 191  EHVFLVESFDLIQEFGLQFQSRL 213
                LV+    + E  L    RL
Sbjct: 2793 VFFKLVDKSTELNEEPLMRFGRL 2815


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  149 bits (376), Expect = 6e-36
 Identities = 82/187 (43%), Positives = 113/187 (60%)

Query: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
           C+  H DLV L+D S SV  ++FE V+++V  +VD  +V P+ TRVG+V++S R  T F 
Sbjct: 32  CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFE 91

Query: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
           LG +G+  EVK A   + Y    T TG ALR++   SFS   G RPR     +V ++ TD
Sbjct: 92  LGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTD 151

Query: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
           GRSQD +   AA A   GI ++AVGVG+A++ EL EIASEP   HV +  DF  +  +  
Sbjct: 152 GRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRG 211

Query: 437 NLRGSIC 443
            LR  +C
Sbjct: 212 KLRRRLC 218



 Score =  134 bits (336), Expect = 3e-31
 Identities = 84/217 (38%), Positives = 118/217 (54%), Gaps = 6/217 (2%)

Query: 10  LLLLLQPWE----TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN 65
           LL +L  W      Q Q  G  C +   DLVF++D+S SV   +FE +RQ++  L+    
Sbjct: 12  LLWMLLLWSGGGGCQAQRAG--CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFE 69

Query: 66  VGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAF 125
           VGP+ TRVGV++YS +  + F L  F  +E+++ A R L      T TG A++Y    +F
Sbjct: 70  VGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSF 129

Query: 126 SVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
           S   G RP +    +VA+++TDGR QD V + AA A   GI I+AVGV  A    L  +A
Sbjct: 130 SPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIA 189

Query: 186 SPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLCNGV 222
           S P   HVF V  F+ I +   + + RLC   LC  V
Sbjct: 190 SEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSV 226


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score =  147 bits (370), Expect = 3e-35
 Identities = 135/452 (29%), Positives = 213/452 (47%), Gaps = 43/452 (9%)

Query: 26   PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
            P   +   D+VF+IDSS  VRP  F  +R F+  ++R LN+GP+  RVGV+Q+S+ V   
Sbjct: 1222 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1281

Query: 86   FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
            F L+ +  +  +  AIR L  L  G+   TG A+++     F  + G+R  E+ VP+  V
Sbjct: 1282 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1339

Query: 144  IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
            +V  G+ QD V+  A   R+ GI    VG +  D   L+ + + P    VF V  F    
Sbjct: 1340 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREF---- 1393

Query: 204  EFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
                        R+L N  +        S G S     P G     D    +R  +   D
Sbjct: 1394 ------------RELPNIEERIMN----SFGPSAATPAPPG----VDTPPPSRPEKKKAD 1433

Query: 264  LVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTA 323
            +V L+DGS + R  +F+ V RFV++IVD +    +  +VGLVQ++S    EF L  + T 
Sbjct: 1434 IVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTK 1493

Query: 324  AEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             ++  A+  V Y   R   T + L H+  + F    G+R     VP++  V T G+S +D
Sbjct: 1494 RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVED 1552

Query: 383  ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG 440
                +    + G+ ++AVGV      E+ +IAS  A    V    +   ++  +LE L  
Sbjct: 1553 AQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHD 1612

Query: 441  ----SICPEEGISAGTELRSPCECESLVEFQG 468
                ++CP  G+   T+    C  + ++ F G
Sbjct: 1613 AMHETLCP--GV---TDAAKACNLDVILGFDG 1639



 Score =  137 bits (345), Expect = 2e-32
 Identities = 120/429 (27%), Positives = 204/429 (47%), Gaps = 32/429 (7%)

Query: 31   GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
            G  D+VF+ID S+S  P EF+ +R  +  L+  L+VG + TRV VIQ+S   +  F L A
Sbjct: 1024 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082

Query: 91   FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
             S +++++ A++ L P   +    G A++Y     F    G+R  EE VP+  V+++ G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1141

Query: 150  PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
              D V + A + +  G+  + +  + AD   L  ++  P  E+VF V +F  +     + 
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 1198

Query: 210  QSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 269
             + +               + + + L+     P   +  A             D+V L+D
Sbjct: 1199 LTPITT----------LTSEQIQKLLASTRYPPPAVESDA------------ADIVFLID 1236

Query: 270  GSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQA 329
             S+ VRP  F  ++ FV++IV  L++ P   RVG+VQFS+ V  EF L  Y + A V  A
Sbjct: 1237 SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 1296

Query: 330  VLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAA 388
            +  +       + TG AL  +  + F ++ G+R     VP+  ++   G+SQDD+S +A 
Sbjct: 1297 IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQDDVSRFAQ 1355

Query: 389  RAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGI 448
              +  GIV   VG       EL+ I ++P    V    +F  + ++ E +  S  P    
Sbjct: 1356 VIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREFRELPNIEERIMNSFGPSAAT 1413

Query: 449  SAGTELRSP 457
             A   + +P
Sbjct: 1414 PAPPGVDTP 1422



 Score =  132 bits (333), Expect = 6e-31
 Identities = 116/415 (27%), Positives = 200/415 (48%), Gaps = 40/415 (9%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D++F+ID S +     F  +  FL+ LL  L +G    RVGV+Q+S + +++F L  +S 
Sbjct: 36  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95

Query: 94  REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           +  +  A++ L   A G +   GLA+ + +   F+ A G+R  EE VP+V V+++ G   
Sbjct: 96  KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSRV-EEGVPQVLVLISAGPSS 153

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           D +       +   +  + +G Q A    L+ +A+   D  VF V  F   + FG   Q 
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF---RSFG-DLQE 207

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
           +L    +               G++ R +  +   +       N+      D+V LVDGS
Sbjct: 208 KLLPYIV---------------GVAQRHIVLKPPTIVTQVIEVNKR-----DIVFLVDGS 247

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            ++   NF  ++ F+ +++  L++  +  +V + Q++  VR EF    + T  EV  AV 
Sbjct: 248 SALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVR 307

Query: 332 AVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            ++ ++   + TG AL  +  + F+ + G R  A  +P++ ++ T G+S D+IS  A   
Sbjct: 308 KMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLDEISQPAQEL 366

Query: 391 KEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLLENLR 439
           K   I+ +A+G   A +AEL EIA +      PAE     AP  G +  LL  LR
Sbjct: 367 KRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLLAPLR 419



 Score =  132 bits (331), Expect = 1e-30
 Identities = 116/434 (26%), Positives = 201/434 (46%), Gaps = 41/434 (9%)

Query: 13  LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
           LL P  T   L+G P  H+   D++F++D S +V    F  +R F+M L+  L++G +  
Sbjct: 414 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470

Query: 72  RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
           RVG++Q+S    + F L  +  + D+   +R L +    G  TG A+ Y     F+ A G
Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530

Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
           +R   E VP++ +++T G+ +D   + A      GI  + VG  +A+   L  +A  P  
Sbjct: 531 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 587

Query: 191 EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
             V+L++ F  +     Q      ++ L   V  G E   +++        PE ++    
Sbjct: 588 SLVYLMDDFSSLPALPQQL-----IQPLTTYVSGGVEEVPLAQ--------PESKR---- 630

Query: 251 GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSR 310
                       D++ L DGS ++  Q F +V+ F+ +I+D L+V PEGTR+ + Q+S  
Sbjct: 631 ------------DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDD 677

Query: 311 VRTEFPLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 369
           V+ E     + +  E+   V  ++    +    G AL +   + F ++ G+R     V +
Sbjct: 678 VKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQ 736

Query: 370 VGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDF 428
             ++   GRS D +   A+  K+ G+V +      A  AEL +I   PA  L     P  
Sbjct: 737 FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKI 796

Query: 429 GTMTHLLENLRGSI 442
           G +   + NL  S+
Sbjct: 797 GDLHPQIVNLLKSV 810



 Score =  124 bits (312), Expect = 2e-28
 Identities = 103/390 (26%), Positives = 187/390 (47%), Gaps = 31/390 (7%)

Query: 30   TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
            +G  D+VF++D S  VR   F  +++F+  ++  L+VG +  RV V+QYS + +  F L 
Sbjct: 819  SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 877

Query: 90   AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
            ++  ++D+  A+R L  L   T  TG A+++ +      + G+R   E VP++ +++T  
Sbjct: 878  SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 936

Query: 149  RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
            R  D V   +   +  G     +G+  AD+  ++ ++  P  +    + +F  +      
Sbjct: 937  RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQV 994

Query: 209  FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
               R+               Q   E LS   L P  + L + G        G  D+V L+
Sbjct: 995  ISERVT--------------QLTREELSR--LQPVLQPLPSPGVG------GKRDVVFLI 1032

Query: 269  DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
            DGS+S  P+ F+ V+  + ++VD+LDV  + TRV ++QFS   + EF L  + +  EV+ 
Sbjct: 1033 DGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 1091

Query: 329  AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
            AV  +     R    G AL ++  + F    G+R     VP+  ++ + G+S D++   A
Sbjct: 1092 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGKSDDEVDDPA 1150

Query: 388  ARAKEEGIVMYAVGVGKAVEAELREIASEP 417
               K+ G+  + +    A + EL +I+  P
Sbjct: 1151 VELKQFGVAPFTI-ARNADQEELVKISLSP 1179



 Score =  117 bits (292), Expect = 3e-26
 Identities = 111/398 (27%), Positives = 173/398 (43%), Gaps = 53/398 (13%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
           D++F+ D S ++   +F  +R FL  ++  LNV P  TR+ V QYS   +V+S F     
Sbjct: 631 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 688

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           S+ E +    R  +   +    G A+ YA    F  + G+R  E+ V +  V++  GR  
Sbjct: 689 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRI-EDGVLQFLVLLVAGRSS 747

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           DRV   A+  +  G+  +    + AD   L  +   P    +   ES   I +   Q   
Sbjct: 748 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQ--- 802

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
              + +L   V +G                                  G  D+V L+DGS
Sbjct: 803 ---IVNLLKSVHNGAPAPV----------------------------SGEKDVVFLLDGS 831

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
           + VR   F L+K FV ++V+ LDV  +  RV +VQ+S R R EF L  Y    +V  AV 
Sbjct: 832 EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 890

Query: 332 AVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            +  +   T  TG AL  ++ +    + G+R     VP++ +V T  RS DD+   +   
Sbjct: 891 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADRSGDDVRNPSVVV 949

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 428
           K  G V   +G+G A   E++ I         S+ PDF
Sbjct: 950 KRGGAVPIGIGIGNADITEMQTI---------SFIPDF 978



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 98/435 (22%), Positives = 178/435 (40%), Gaps = 72/435 (16%)

Query: 25   GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
            GP  C   P +L F +D+S  V    F  MR  ++ ++  L +     P   RV V+ Y+
Sbjct: 2186 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 2245

Query: 80   SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
            ++V +        R+  +   I++L    Q  +T    Q ++  A S    AR   +RV 
Sbjct: 2246 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRVR 2297

Query: 140  ------RVAVIV--TDGRPQDRVAEVAAQARARGIE-IYAVGVQRADVGSLRAMASPPLD 190
                  +VAV    T  R   ++ E   +    GI  ++    +   + +   + +  + 
Sbjct: 2298 NGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVG 2357

Query: 191  EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
              + L    DL           +C+ D+CN +D  C F       S+R   P  R  +A 
Sbjct: 2358 HALVLPAGRDLTDFLENVLTCHVCL-DICN-IDPSCGFG------SWR---PSFRDRRAA 2406

Query: 251  GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGL 304
            G   +      +D+  ++D +++     F  +K+++  +V  LD+SP+        RV +
Sbjct: 2407 GSDVD------IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAV 2460

Query: 305  VQFSSR----------VRTEFPLGRYGTAAEVKQAVLAVEYMERG-------TMTGLALR 347
            VQ +            V+ EF L  YG+  ++      V+++ RG          G A+ 
Sbjct: 2461 VQHAPSESVDNASMPPVKVEFSLTDYGSKEKL------VDFLSRGMTQLQGTRALGSAIE 2514

Query: 348  HMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAV 406
            + +E+ F  A    PR L +  + L       Q ++      +AK +G     +G+G+ V
Sbjct: 2515 YTIENVFESA--PNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKV 2572

Query: 407  E-AELREIASEPAEL 420
               E+   ASEP ++
Sbjct: 2573 NIKEVYTFASEPNDV 2587



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
            +D+ F++DS+ +   F+F  M++++  L+R L++ P+        RV V+Q++       
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471

Query: 82   -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
                 V+  F L  +  +E +   +   +   QGT   G AI+Y +   F  A     P 
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2526

Query: 136  ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
             R  ++ V++  G  P+ ++ E   V  QA+ +G     +G+ ++ ++  +   AS P D
Sbjct: 2527 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2586

Query: 191  EHVFLVESFDLIQEFGLQFQSRL 213
                LV+    + E  L    RL
Sbjct: 2587 VFFKLVDKSTELNEEPLMRFGRL 2609


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score =  147 bits (370), Expect = 3e-35
 Identities = 135/452 (29%), Positives = 213/452 (47%), Gaps = 43/452 (9%)

Query: 26   PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
            P   +   D+VF+IDSS  VRP  F  +R F+  ++R LN+GP+  RVGV+Q+S+ V   
Sbjct: 821  PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 880

Query: 86   FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
            F L+ +  +  +  AIR L  L  G+   TG A+++     F  + G+R  E+ VP+  V
Sbjct: 881  FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 938

Query: 144  IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
            +V  G+ QD V+  A   R+ GI    VG +  D   L+ + + P    VF V  F    
Sbjct: 939  LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREF---- 992

Query: 204  EFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVD 263
                        R+L N  +        S G S     P G     D    +R  +   D
Sbjct: 993  ------------RELPNIEERIMN----SFGPSAATPAPPG----VDTPPPSRPEKKKAD 1032

Query: 264  LVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTA 323
            +V L+DGS + R  +F+ V RFV++IVD +    +  +VGLVQ++S    EF L  + T 
Sbjct: 1033 IVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTK 1092

Query: 324  AEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             ++  A+  V Y   R   T + L H+  + F    G+R     VP++  V T G+S +D
Sbjct: 1093 RQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVED 1151

Query: 383  ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG 440
                +    + G+ ++AVGV      E+ +IAS  A    V    +   ++  +LE L  
Sbjct: 1152 AQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHD 1211

Query: 441  ----SICPEEGISAGTELRSPCECESLVEFQG 468
                ++CP  G+   T+    C  + ++ F G
Sbjct: 1212 AMHETLCP--GV---TDAAKACNLDVILGFDG 1238



 Score =  137 bits (345), Expect = 2e-32
 Identities = 120/429 (27%), Positives = 204/429 (47%), Gaps = 32/429 (7%)

Query: 31   GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
            G  D+VF+ID S+S  P EF+ +R  +  L+  L+VG + TRV VIQ+S   +  F L A
Sbjct: 623  GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681

Query: 91   FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
             S +++++ A++ L P   +    G A++Y     F    G+R  EE VP+  V+++ G+
Sbjct: 682  HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 740

Query: 150  PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
              D V + A + +  G+  + +  + AD   L  ++  P  E+VF V +F  +     + 
Sbjct: 741  SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 797

Query: 210  QSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 269
             + +               + + + L+     P   +  A             D+V L+D
Sbjct: 798  LTPITT----------LTSEQIQKLLASTRYPPPAVESDA------------ADIVFLID 835

Query: 270  GSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQA 329
             S+ VRP  F  ++ FV++IV  L++ P   RVG+VQFS+ V  EF L  Y + A V  A
Sbjct: 836  SSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDA 895

Query: 330  VLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAA 388
            +  +       + TG AL  +  + F ++ G+R     VP+  ++   G+SQDD+S +A 
Sbjct: 896  IRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIED-GVPQHLVLVLGGKSQDDVSRFAQ 954

Query: 389  RAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGI 448
              +  GIV   VG       EL+ I ++P    V    +F  + ++ E +  S  P    
Sbjct: 955  VIRSSGIVSLGVGDRNIDRTELQTITNDPR--LVFTVREFRELPNIEERIMNSFGPSAAT 1012

Query: 449  SAGTELRSP 457
             A   + +P
Sbjct: 1013 PAPPGVDTP 1021



 Score =  124 bits (312), Expect = 2e-28
 Identities = 103/390 (26%), Positives = 187/390 (47%), Gaps = 31/390 (7%)

Query: 30  TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
           +G  D+VF++D S  VR   F  +++F+  ++  L+VG +  RV V+QYS + +  F L 
Sbjct: 418 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 476

Query: 90  AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
           ++  ++D+  A+R L  L   T  TG A+++ +      + G+R   E VP++ +++T  
Sbjct: 477 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 535

Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
           R  D V   +   +  G     +G+  AD+  ++ ++  P  +    + +F  +      
Sbjct: 536 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQV 593

Query: 209 FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
              R+               Q   E LS   L P  + L + G        G  D+V L+
Sbjct: 594 ISERVT--------------QLTREELSR--LQPVLQPLPSPGVG------GKRDVVFLI 631

Query: 269 DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
           DGS+S  P+ F+ V+  + ++VD+LDV  + TRV ++QFS   + EF L  + +  EV+ 
Sbjct: 632 DGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 690

Query: 329 AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
           AV  +     R    G AL ++  + F    G+R     VP+  ++ + G+S D++   A
Sbjct: 691 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGKSDDEVDDPA 749

Query: 388 ARAKEEGIVMYAVGVGKAVEAELREIASEP 417
              K+ G+  + +    A + EL +I+  P
Sbjct: 750 VELKQFGVAPFTI-ARNADQEELVKISLSP 778



 Score =  117 bits (292), Expect = 3e-26
 Identities = 111/398 (27%), Positives = 173/398 (43%), Gaps = 53/398 (13%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
           D++F+ D S ++   +F  +R FL  ++  LNV P  TR+ V QYS   +V+S F     
Sbjct: 230 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 287

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           S+ E +    R  +   +    G A+ YA    F  + G+R  E+ V +  V++  GR  
Sbjct: 288 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRI-EDGVLQFLVLLVAGRSS 346

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           DRV   A+  +  G+  +    + AD   L  +   P    +   ES   I +   Q   
Sbjct: 347 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQ--- 401

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
              + +L   V +G                                  G  D+V L+DGS
Sbjct: 402 ---IVNLLKSVHNGAPAPV----------------------------SGEKDVVFLLDGS 430

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
           + VR   F L+K FV ++V+ LDV  +  RV +VQ+S R R EF L  Y    +V  AV 
Sbjct: 431 EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 489

Query: 332 AVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            +  +   T  TG AL  ++ +    + G+R     VP++ +V T  RS DD+   +   
Sbjct: 490 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADRSGDDVRNPSVVV 548

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 428
           K  G V   +G+G A   E++ I         S+ PDF
Sbjct: 549 KRGGAVPIGIGIGNADITEMQTI---------SFIPDF 577



 Score =  116 bits (291), Expect = 4e-26
 Identities = 105/413 (25%), Positives = 185/413 (44%), Gaps = 45/413 (10%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+VF++D S ++    F  +R F+  +++ L +G +  +V V QY+  V+  F       
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 94  REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
           + ++  A+R + PL      TG A+ +  N  F+ + G R   E +P++ V++T G+  D
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156

Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSR 212
            +++ A + +   I  +A+G + AD   L  +A                       F S 
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA-----------------------FDSS 193

Query: 213 LCVRDLCNGVDHGCEFQCVS-EGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
           L        V    EF+    +G+    L P  R L    +   R      D++ L DGS
Sbjct: 194 L--------VFIPAEFRAAPLQGMLPGLLAPL-RTLSGTPEESKR------DILFLFDGS 238

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            ++  Q F +V+ F+ +I+D L+V PEGTR+ + Q+S  V+ E     + +  E+   V 
Sbjct: 239 ANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVK 297

Query: 332 AVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            ++    +    G AL +   + F ++ G+R     V +  ++   GRS D +   A+  
Sbjct: 298 RMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAGRSSDRVDGPASNL 356

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLENLRGSI 442
           K+ G+V +      A  AEL +I   PA  L     P  G +   + NL  S+
Sbjct: 357 KQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSV 409



 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 63/192 (32%), Positives = 102/192 (53%), Gaps = 11/192 (5%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           D+V LVDGS ++   NF  ++ F+ +++  L++  +  +V + Q++  VR EF    + T
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 323 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 381
             EV  AV  ++ ++   + TG AL  +  + F+ + G R  A  +P++ ++ T G+S D
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156

Query: 382 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 435
           +IS  A   K   I+ +A+G   A +AEL EIA +      PAE     AP  G +  LL
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 214

Query: 436 ENLRG-SICPEE 446
             LR  S  PEE
Sbjct: 215 APLRTLSGTPEE 226



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 98/435 (22%), Positives = 178/435 (40%), Gaps = 72/435 (16%)

Query: 25   GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
            GP  C   P +L F +D+S  V    F  MR  ++ ++  L +     P   RV V+ Y+
Sbjct: 1785 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 1844

Query: 80   SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
            ++V +        R+  +   I++L    Q  +T    Q ++  A S    AR   +RV 
Sbjct: 1845 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRVR 1896

Query: 140  ------RVAVIV--TDGRPQDRVAEVAAQARARGIE-IYAVGVQRADVGSLRAMASPPLD 190
                  +VAV    T  R   ++ E   +    GI  ++    +   + +   + +  + 
Sbjct: 1897 NGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVG 1956

Query: 191  EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
              + L    DL           +C+ D+CN +D  C F       S+R   P  R  +A 
Sbjct: 1957 HALVLPAGRDLTDFLENVLTCHVCL-DICN-IDPSCGFG------SWR---PSFRDRRAA 2005

Query: 251  GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGL 304
            G   +      +D+  ++D +++     F  +K+++  +V  LD+SP+        RV +
Sbjct: 2006 GSDVD------IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAV 2059

Query: 305  VQFSSR----------VRTEFPLGRYGTAAEVKQAVLAVEYMERG-------TMTGLALR 347
            VQ +            V+ EF L  YG+  ++      V+++ RG          G A+ 
Sbjct: 2060 VQHAPSESVDNASMPPVKVEFSLTDYGSKEKL------VDFLSRGMTQLQGTRALGSAIE 2113

Query: 348  HMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAV 406
            + +E+ F  A    PR L +  + L       Q ++      +AK +G     +G+G+ V
Sbjct: 2114 YTIENVFESA--PNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKV 2171

Query: 407  E-AELREIASEPAEL 420
               E+   ASEP ++
Sbjct: 2172 NIKEVYTFASEPNDV 2186



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
            +D+ F++DS+ +   F+F  M++++  L+R L++ P+        RV V+Q++       
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070

Query: 82   -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
                 V+  F L  +  +E +   +   +   QGT   G AI+Y +   F  A     P 
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2125

Query: 136  ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
             R  ++ V++  G  P+ ++ E   V  QA+ +G     +G+ ++ ++  +   AS P D
Sbjct: 2126 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2185

Query: 191  EHVFLVESFDLIQEFGLQFQSRL 213
                LV+    + E  L    RL
Sbjct: 2186 VFFKLVDKSTELNEEPLMRFGRL 2208


>gi|205277471 cochlin precursor [Homo sapiens]
          Length = 550

 Score =  145 bits (367), Expect = 6e-35
 Identities = 108/426 (25%), Positives = 185/426 (43%), Gaps = 64/426 (15%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+ F+ID S ++    F   + F+  +   L +G     VG++Q S   +  F L+ F+ 
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224

Query: 94  REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
            +D+  AI+++      + TG A+++     F+V  G R   + +P+V V+  DG P D 
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281

Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--------- 204
           + E    AR  G+ ++ V V +            P+ E + +V+    + +         
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK------------PIPEELGMVQDVTFVDKAVCRNNGFF 329

Query: 205 -------FGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRC 257
                  FG     +  V+ LC      C   C +                         
Sbjct: 330 SYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNS------------------------ 365

Query: 258 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPL 317
               V++  L+DGS SV   NF L+  FV+ I    ++S  G ++  VQF+   RTEF  
Sbjct: 366 ----VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSF 421

Query: 318 GRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 377
             Y T   V   +  + YM  GT TG A+   V + F   + +  +   V     + TDG
Sbjct: 422 TDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----IVTDG 476

Query: 378 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLEN 437
           +S DD+   AA A + GI +++VGV  A   +L+++AS+P E H  +  +F  +  ++ +
Sbjct: 477 QSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSD 536

Query: 438 LRGSIC 443
           +   IC
Sbjct: 537 VIRGIC 542



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 242 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 301
           P G++L+   +     ++   D+  L+DGS ++  + F L K FV ++   L +  EG  
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203

Query: 302 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 361
           VGLVQ S   + EF L  + +A +V  A+  V +    + TG AL+H  +  F+   G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263

Query: 362 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 410
                +P+V +VF DG   DDI      A+E G+ ++ V V K +  EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)

Query: 13  LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
           L+Q   T  Q+   +     +++ F+ID S SV    F  M +F+  + +   +     +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405

Query: 73  VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
           +  +Q++   ++ F    +S +E++   IR++  ++ GT TG AI + +   F       
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462

Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
             E       VIVTDG+  D V   AA A   GI I++VGV  A +  L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520

Query: 193 VFLVESF 199
            F    F
Sbjct: 521 AFFTREF 527


>gi|4758022 cochlin precursor [Homo sapiens]
          Length = 550

 Score =  145 bits (367), Expect = 6e-35
 Identities = 108/426 (25%), Positives = 185/426 (43%), Gaps = 64/426 (15%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+ F+ID S ++    F   + F+  +   L +G     VG++Q S   +  F L+ F+ 
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224

Query: 94  REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
            +D+  AI+++      + TG A+++     F+V  G R   + +P+V V+  DG P D 
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281

Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--------- 204
           + E    AR  G+ ++ V V +            P+ E + +V+    + +         
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK------------PIPEELGMVQDVTFVDKAVCRNNGFF 329

Query: 205 -------FGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRC 257
                  FG     +  V+ LC      C   C +                         
Sbjct: 330 SYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNS------------------------ 365

Query: 258 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPL 317
               V++  L+DGS SV   NF L+  FV+ I    ++S  G ++  VQF+   RTEF  
Sbjct: 366 ----VNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSF 421

Query: 318 GRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 377
             Y T   V   +  + YM  GT TG A+   V + F   + +  +   V     + TDG
Sbjct: 422 TDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----IVTDG 476

Query: 378 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLEN 437
           +S DD+   AA A + GI +++VGV  A   +L+++AS+P E H  +  +F  +  ++ +
Sbjct: 477 QSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSD 536

Query: 438 LRGSIC 443
           +   IC
Sbjct: 537 VIRGIC 542



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)

Query: 242 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 301
           P G++L+   +     ++   D+  L+DGS ++  + F L K FV ++   L +  EG  
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203

Query: 302 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 361
           VGLVQ S   + EF L  + +A +V  A+  V +    + TG AL+H  +  F+   G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263

Query: 362 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 410
                +P+V +VF DG   DDI      A+E G+ ++ V V K +  EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)

Query: 13  LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
           L+Q   T  Q+   +     +++ F+ID S SV    F  M +F+  + +   +     +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405

Query: 73  VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
           +  +Q++   ++ F    +S +E++   IR++  ++ GT TG AI + +   F       
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462

Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
             E       VIVTDG+  D V   AA A   GI I++VGV  A +  L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520

Query: 193 VFLVESF 199
            F    F
Sbjct: 521 AFFTREF 527


>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1036

 Score =  143 bits (361), Expect = 3e-34
 Identities = 115/408 (28%), Positives = 197/408 (48%), Gaps = 43/408 (10%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D+VF++D S ++    F  +R F+  +++ L +G +  +V V QY+  V+  F       
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 94  REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
           + ++  A+R + PL      TG A+ +  N  F+ + G R   E +P++ V++T G+  D
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156

Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSR 212
            +++ A + +   I  +A+G + AD   L  +A                       F S 
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA-----------------------FDSS 193

Query: 213 LCVRDLCNGVDHGCEFQCVS-EGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
           L        V    EF+    +G+    L P  R L    +  +  R    D++ L+DGS
Sbjct: 194 L--------VFIPAEFRAAPLQGMLPGLLAPL-RTLSGTPEVHSNKR----DIIFLLDGS 240

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            +V   NF  V+ FV  +V+ LD+  +  RVGLVQFS    TEF L  Y T +++   + 
Sbjct: 241 ANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLR 300

Query: 332 AVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            ++     G  TG AL ++  + F+EA G+R R  +VP++ L+ T G+S+D     A   
Sbjct: 301 QLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSEDSYLQAANAL 359

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 438
              GI+ + VG  +A +AEL +IA  P+ +++    DF ++  L + L
Sbjct: 360 TRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 405



 Score =  132 bits (331), Expect = 1e-30
 Identities = 116/434 (26%), Positives = 201/434 (46%), Gaps = 41/434 (9%)

Query: 13  LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
           LL P  T   L+G P  H+   D++F++D S +V    F  +R F+M L+  L++G +  
Sbjct: 213 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 269

Query: 72  RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
           RVG++Q+S    + F L  +  + D+   +R L +    G  TG A+ Y     F+ A G
Sbjct: 270 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 329

Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
           +R   E VP++ +++T G+ +D   + A      GI  + VG  +A+   L  +A  P  
Sbjct: 330 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 386

Query: 191 EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
             V+L++ F  +     Q      ++ L   V  G E   +++        PE ++    
Sbjct: 387 SLVYLMDDFSSLPALPQQL-----IQPLTTYVSGGVEEVPLAQ--------PESKR---- 429

Query: 251 GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSR 310
                       D++ L DGS ++  Q F +V+ F+ +I+D L+V PEGTR+ + Q+S  
Sbjct: 430 ------------DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDD 476

Query: 311 VRTEFPLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 369
           V+ E     + +  E+   V  ++    +    G AL +   + F ++ G+R     V +
Sbjct: 477 VKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQ 535

Query: 370 VGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDF 428
             ++   GRS D +   A+  K+ G+V +      A  AEL +I   PA  L     P  
Sbjct: 536 FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKI 595

Query: 429 GTMTHLLENLRGSI 442
           G +   + NL  S+
Sbjct: 596 GDLHPQIVNLLKSV 609



 Score =  124 bits (312), Expect = 2e-28
 Identities = 103/390 (26%), Positives = 187/390 (47%), Gaps = 31/390 (7%)

Query: 30  TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
           +G  D+VF++D S  VR   F  +++F+  ++  L+VG +  RV V+QYS + +  F L 
Sbjct: 618 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 676

Query: 90  AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
           ++  ++D+  A+R L  L   T  TG A+++ +      + G+R   E VP++ +++T  
Sbjct: 677 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 735

Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
           R  D V   +   +  G     +G+  AD+  ++ ++  P  +    + +F  +      
Sbjct: 736 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQV 793

Query: 209 FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
              R+               Q   E LS   L P  + L + G        G  D+V L+
Sbjct: 794 ISERVT--------------QLTREELSR--LQPVLQPLPSPGVG------GKRDVVFLI 831

Query: 269 DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
           DGS+S  P+ F+ V+  + ++VD+LDV  + TRV ++QFS   + EF L  + +  EV+ 
Sbjct: 832 DGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 890

Query: 329 AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
           AV  +     R    G AL ++  + F    G+R     VP+  ++ + G+S D++   A
Sbjct: 891 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGKSDDEVDDPA 949

Query: 388 ARAKEEGIVMYAVGVGKAVEAELREIASEP 417
              K+ G+  + +    A + EL +I+  P
Sbjct: 950 VELKQFGVAPFTI-ARNADQEELVKISLSP 978



 Score =  117 bits (292), Expect = 3e-26
 Identities = 111/398 (27%), Positives = 173/398 (43%), Gaps = 53/398 (13%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
           D++F+ D S ++   +F  +R FL  ++  LNV P  TR+ V QYS   +V+S F     
Sbjct: 430 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 487

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           S+ E +    R  +   +    G A+ YA    F  + G+R  E+ V +  V++  GR  
Sbjct: 488 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRI-EDGVLQFLVLLVAGRSS 546

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           DRV   A+  +  G+  +    + AD   L  +   P    +   ES   I +   Q   
Sbjct: 547 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQ--- 601

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
              + +L   V +G                                  G  D+V L+DGS
Sbjct: 602 ---IVNLLKSVHNGAPAPV----------------------------SGEKDVVFLLDGS 630

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
           + VR   F L+K FV ++V+ LDV  +  RV +VQ+S R R EF L  Y    +V  AV 
Sbjct: 631 EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 689

Query: 332 AVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            +  +   T  TG AL  ++ +    + G+R     VP++ +V T  RS DD+   +   
Sbjct: 690 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADRSGDDVRNPSVVV 748

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 428
           K  G V   +G+G A   E++ I         S+ PDF
Sbjct: 749 KRGGAVPIGIGIGNADITEMQTI---------SFIPDF 777



 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           D+V LVDGS ++   NF  ++ F+ +++  L++  +  +V + Q++  VR EF    + T
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97

Query: 323 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 381
             EV  AV  ++ ++   + TG AL  +  + F+ + G R  A  +P++ ++ T G+S D
Sbjct: 98  KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156

Query: 382 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 435
           +IS  A   K   I+ +A+G   A +AEL EIA +      PAE     AP  G +  LL
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 214

Query: 436 ENLR 439
             LR
Sbjct: 215 APLR 218



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)

Query: 31  GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
           G  D+VF+ID S+S  P EF+ +R  +  L+  L+VG + TRV VIQ+S   +  F L A
Sbjct: 823 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881

Query: 91  FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
            S +++++ A++ L P   +    G A++Y     F    G+R  EE VP+  V+++ G+
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 940

Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
             D V + A + +  G+  + +  + AD   L  ++  P  E+VF V +F
Sbjct: 941 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 987


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
           [Homo sapiens]
          Length = 1899

 Score =  134 bits (338), Expect = 1e-31
 Identities = 67/197 (34%), Positives = 118/197 (59%), Gaps = 5/197 (2%)

Query: 247 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 306
           ++A+G  C        D+VLLVDGS S+   NF  V+ F+++IV+  D+ P+  ++ L Q
Sbjct: 21  IEAEGMEC--LTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78

Query: 307 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 366
           +S   RTE+ L  +     + QAV  + Y    T+TG+AL  + + +F    G RPRA  
Sbjct: 79  YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA-- 136

Query: 367 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAP 426
             ++G++ TDG+SQDD+   + + K+EG+ ++A+G+  A E EL+ IA++P + H     
Sbjct: 137 -RKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195

Query: 427 DFGTMTHLLENLRGSIC 443
           DF +++ ++++L  ++C
Sbjct: 196 DFESLSRIVDDLTINLC 212



 Score =  110 bits (274), Expect = 4e-24
 Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)

Query: 257  CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 315
            C+    D+V L D S S+   NF  V +F+ N +  F ++SP G +V  VQ+S  V++EF
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212

Query: 316  PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 375
             L  Y   A    A+  + Y    T TG AL  + E   +   G R    NVP+V +V T
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 1269

Query: 376  DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 435
            DGRSQD++   A   ++ G  ++ VGV      EL  IAS+P+E HV    DF +   + 
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 1329

Query: 436  ENLRGSIC 443
            +NL   +C
Sbjct: 1330 DNLITFVC 1337



 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 52/197 (26%), Positives = 101/197 (51%), Gaps = 4/197 (2%)

Query: 19  TQLQLTGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQ 77
           + ++  G  C T    D+V ++D S S+    F T+R F+  ++   ++GP   ++ + Q
Sbjct: 19  SSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78

Query: 78  YSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEER 137
           YS   ++ + L A   ++ + +A+ +L      T+TG+A+ +     F    G RP   R
Sbjct: 79  YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---R 135

Query: 138 VPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVE 197
             ++ V++TDG+ QD V   + + +  G+E++A+G++ AD   L+ +A+ P D H + V 
Sbjct: 136 ARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195

Query: 198 SFDLIQEFGLQFQSRLC 214
            F+ +          LC
Sbjct: 196 DFESLSRIVDDLTINLC 212



 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)

Query: 28   CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
            C     D+VF+ D+S S+    F  + +F+   + G + + P   +V  +QYS +V+S F
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212

Query: 87   PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
             L  ++ +     A++++      T TG A+ +      +   G R   + VP+V V+VT
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 1269

Query: 147  DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
            DGR QD V + A   +  G  ++ VGV   D   L  +AS P + HVF+V+ F+  ++
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 1327


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score =  134 bits (336), Expect = 3e-31
 Identities = 74/181 (40%), Positives = 109/181 (60%), Gaps = 3/181 (1%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           D+V+LVDGS S+   NF LV+ F+  +V   DV  E TR+GL Q+S   R E+ L  + T
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217

Query: 323 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             EV +AV  + Y    T+TGLAL ++ E+SF    G+R     V ++G++ TDG+SQDD
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILITDGKSQDD 274

Query: 383 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
           I   +   +E G+ ++A+GV  A   EL+EIASEP   HV    +F  M  ++E+L  ++
Sbjct: 275 IIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTL 334

Query: 443 C 443
           C
Sbjct: 335 C 335



 Score =  119 bits (298), Expect = 6e-27
 Identities = 65/190 (34%), Positives = 104/190 (54%), Gaps = 4/190 (2%)

Query: 28  CHTGPL-DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
           C T  + D+V ++D S S+  F F  +R FL  L+   +VG   TR+G+ QYS   +  +
Sbjct: 151 CQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEW 210

Query: 87  PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
            L AFS ++++  A+R+L      T+TGLA+ Y    +F    G+R     V ++ +++T
Sbjct: 211 HLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILIT 267

Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
           DG+ QD +   +   R  G+E++A+GV+ ADV  L+ +AS P   HV+ V  FDL+    
Sbjct: 268 DGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVV 327

Query: 207 LQFQSRLCVR 216
                 LC R
Sbjct: 328 ESLTRTLCSR 337



 Score =  111 bits (277), Expect = 2e-24
 Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 4/188 (2%)

Query: 257  CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 315
            C+    DLV +VDGS S+  +NF  +  F+   V  L+ +  +GT+V +VQF+   RTEF
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085

Query: 316  PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 375
             L  Y T   +  A+  + Y    T TG A++++ +  F+   G R     +P+V +V T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRR---GIPKVIVVIT 1142

Query: 376  DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 435
            DGRSQDD++  +   + +G  ++A+GV  A  +EL  I S+P+  HV +  DF     + 
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202

Query: 436  ENLRGSIC 443
            + L   +C
Sbjct: 1203 DELITFVC 1210



 Score =  107 bits (267), Expect = 3e-23
 Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 4/188 (2%)

Query: 28   CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
            C     DLVF++D S S+    F  +  FL   +  LN +G + T+V ++Q++   ++ F
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085

Query: 87   PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
             L A+  +E +  AI+ +      T TG AI+Y  +  F+   G R     +P+V V++T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTR---RGIPKVIVVIT 1142

Query: 147  DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
            DGR QD V +++ + +  G  I+A+GV  AD   L ++ S P   HVF V+ FD  ++  
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202

Query: 207  LQFQSRLC 214
             +  + +C
Sbjct: 1203 DELITFVC 1210


>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
           sapiens]
          Length = 1237

 Score =  132 bits (333), Expect = 6e-31
 Identities = 116/415 (27%), Positives = 200/415 (48%), Gaps = 40/415 (9%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
           D++F+ID S +     F  +  FL+ LL  L +G    RVGV+Q+S + +++F L  +S 
Sbjct: 36  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95

Query: 94  REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           +  +  A++ L   A G +   GLA+ + +   F+ A G+R  EE VP+V V+++ G   
Sbjct: 96  KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSRV-EEGVPQVLVLISAGPSS 153

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           D +       +   +  + +G Q A    L+ +A+   D  VF V  F   + FG   Q 
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF---RSFG-DLQE 207

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
           +L    +               G++ R +  +   +       N+      D+V LVDGS
Sbjct: 208 KLLPYIV---------------GVAQRHIVLKPPTIVTQVIEVNKR-----DIVFLVDGS 247

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
            ++   NF  ++ F+ +++  L++  +  +V + Q++  VR EF    + T  EV  AV 
Sbjct: 248 SALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVR 307

Query: 332 AVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            ++ ++   + TG AL  +  + F+ + G R  A  +P++ ++ T G+S D+IS  A   
Sbjct: 308 KMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLDEISQPAQEL 366

Query: 391 KEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLLENLR 439
           K   I+ +A+G   A +AEL EIA +      PAE     AP  G +  LL  LR
Sbjct: 367 KRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLLAPLR 419



 Score =  132 bits (331), Expect = 1e-30
 Identities = 116/434 (26%), Positives = 201/434 (46%), Gaps = 41/434 (9%)

Query: 13  LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
           LL P  T   L+G P  H+   D++F++D S +V    F  +R F+M L+  L++G +  
Sbjct: 414 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470

Query: 72  RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
           RVG++Q+S    + F L  +  + D+   +R L +    G  TG A+ Y     F+ A G
Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530

Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
           +R   E VP++ +++T G+ +D   + A      GI  + VG  +A+   L  +A  P  
Sbjct: 531 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 587

Query: 191 EHVFLVESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQAD 250
             V+L++ F  +     Q      ++ L   V  G E   +++        PE ++    
Sbjct: 588 SLVYLMDDFSSLPALPQQL-----IQPLTTYVSGGVEEVPLAQ--------PESKR---- 630

Query: 251 GKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSR 310
                       D++ L DGS ++  Q F +V+ F+ +I+D L+V PEGTR+ + Q+S  
Sbjct: 631 ------------DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDD 677

Query: 311 VRTEFPLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 369
           V+ E     + +  E+   V  ++    +    G AL +   + F ++ G+R     V +
Sbjct: 678 VKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQ 736

Query: 370 VGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDF 428
             ++   GRS D +   A+  K+ G+V +      A  AEL +I   PA  L     P  
Sbjct: 737 FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKI 796

Query: 429 GTMTHLLENLRGSI 442
           G +   + NL  S+
Sbjct: 797 GDLHPQIVNLLKSV 810



 Score =  124 bits (312), Expect = 2e-28
 Identities = 103/390 (26%), Positives = 187/390 (47%), Gaps = 31/390 (7%)

Query: 30   TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
            +G  D+VF++D S  VR   F  +++F+  ++  L+VG +  RV V+QYS + +  F L 
Sbjct: 819  SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 877

Query: 90   AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
            ++  ++D+  A+R L  L   T  TG A+++ +      + G+R   E VP++ +++T  
Sbjct: 878  SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 936

Query: 149  RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
            R  D V   +   +  G     +G+  AD+  ++ ++  P  +    + +F  +      
Sbjct: 937  RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP--DFAVAIPTFRQLGTVQQV 994

Query: 209  FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
               R+               Q   E LS   L P  + L + G        G  D+V L+
Sbjct: 995  ISERVT--------------QLTREELSR--LQPVLQPLPSPGVG------GKRDVVFLI 1032

Query: 269  DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
            DGS+S  P+ F+ V+  + ++VD+LDV  + TRV ++QFS   + EF L  + +  EV+ 
Sbjct: 1033 DGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNAHSSKDEVQN 1091

Query: 329  AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
            AV  +     R    G AL ++  + F    G+R     VP+  ++ + G+S D++   A
Sbjct: 1092 AVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGKSDDEVDDPA 1150

Query: 388  ARAKEEGIVMYAVGVGKAVEAELREIASEP 417
               K+ G+  + +    A + EL +I+  P
Sbjct: 1151 VELKQFGVAPFTI-ARNADQEELVKISLSP 1179



 Score =  117 bits (292), Expect = 3e-26
 Identities = 111/398 (27%), Positives = 173/398 (43%), Gaps = 53/398 (13%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
           D++F+ D S ++   +F  +R FL  ++  LNV P  TR+ V QYS   +V+S F     
Sbjct: 631 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 688

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           S+ E +    R  +   +    G A+ YA    F  + G+R  E+ V +  V++  GR  
Sbjct: 689 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRI-EDGVLQFLVLLVAGRSS 747

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           DRV   A+  +  G+  +    + AD   L  +   P    +   ES   I +   Q   
Sbjct: 748 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPA--FILAAESLPKIGDLHPQ--- 802

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGS 271
              + +L   V +G                                  G  D+V L+DGS
Sbjct: 803 ---IVNLLKSVHNGAPAPV----------------------------SGEKDVVFLLDGS 831

Query: 272 KSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVL 331
           + VR   F L+K FV ++V+ LDV  +  RV +VQ+S R R EF L  Y    +V  AV 
Sbjct: 832 EGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVR 890

Query: 332 AVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARA 390
            +  +   T  TG AL  ++ +    + G+R     VP++ +V T  RS DD+   +   
Sbjct: 891 QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADRSGDDVRNPSVVV 949

Query: 391 KEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 428
           K  G V   +G+G A   E++ I         S+ PDF
Sbjct: 950 KRGGAVPIGIGIGNADITEMQTI---------SFIPDF 978



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)

Query: 31   GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
            G  D+VF+ID S+S  P EF+ +R  +  L+  L+VG + TRV VIQ+S   +  F L A
Sbjct: 1024 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082

Query: 91   FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
             S +++++ A++ L P   +    G A++Y     F    G+R  EE VP+  V+++ G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1141

Query: 150  PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
              D V + A + +  G+  + +  + AD   L  ++  P  E+VF V +F
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1188


>gi|38348304 von Willebrand factor A domain containing 2 [Homo
           sapiens]
          Length = 725

 Score =  132 bits (332), Expect = 7e-31
 Identities = 113/401 (28%), Positives = 181/401 (45%), Gaps = 55/401 (13%)

Query: 33  LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
           +DL+F++DSS       F   + F+   +R +    +  RVGV  YS ++    P+  + 
Sbjct: 342 VDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEYQ 401

Query: 93  RREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
              D+  ++ D +P   G T+TG A++ A    F  A   R  ++R  RV V++T+   +
Sbjct: 402 DVPDLVWSL-DGIPFRGGPTLTGSALRQAAERGFGSA--TRTGQDRPRRVVVLLTESHSE 458

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           D VA  A  ARAR + +  VG +           SP   +HV +                
Sbjct: 459 DEVAGPARHARARELLLLGVGSEAVRAELEEITGSP---KHVMVYSD------------- 502

Query: 212 RLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR----CREGHVDLVLL 267
               +DL N +                         +  GK C+R    CR   +DLV +
Sbjct: 503 ---PQDLFNQIP------------------------ELQGKLCSRQRPGCRTQALDLVFM 535

Query: 268 VDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVK 327
           +D S SV P+NF  ++ FV       +V+P+ T+VGLV + S+V+T F L    T A + 
Sbjct: 536 LDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTAFGLDTKPTRAAML 595

Query: 328 QAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
           +A+    Y+      G AL H+ +   +  +GARP    VP+  +V T GR  +D +V A
Sbjct: 596 RAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP---GVPKAVVVLTGGRGAEDAAVPA 652

Query: 388 ARAKEEGIVMYAVGVGKAVEAELREIAS-EPAELHVSYAPD 427
            + +  GI +  VGVG  +   LR +A    + +HV+   D
Sbjct: 653 QKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHVAAYAD 693



 Score =  125 bits (314), Expect = 9e-29
 Identities = 128/487 (26%), Positives = 203/487 (41%), Gaps = 88/487 (18%)

Query: 33  LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
           +D++F++D S SV    FE  + F + +  GL++ P   RVG  Q+SS     FPL +FS
Sbjct: 50  VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109

Query: 93  RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
            +++++  I+ +V     T T LA++Y ++        A      VP++ +IVTDG+ Q 
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164

Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--FGLQFQ 210
            VA  + Q + RG+ ++AVGV+      L A+AS P  +HV L E  +      F     
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224

Query: 211 SRLC--VRDLCNGVDHGCEFQCVS------------------------------------ 232
           S +C      C    H CE + +                                     
Sbjct: 225 SAICSSATPDCRVEAHPCEHRTLEMVREFAGNAPCWRGSRRTLAVLAAHCPFYSWKRVFL 284

Query: 233 --EGLSYRCLCP---EGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVN 287
                 YR  CP   + +  Q  G       +G+  L  L  G ++       L  R   
Sbjct: 285 THPATCYRTTCPGPCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCALKLSLECRV-- 342

Query: 288 QIVDFLDVSPEGT-------RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAV---EYME 337
            ++  LD S   T       +V + +F   V +E    R G A   ++ ++AV   EY +
Sbjct: 343 DLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEYQD 402

Query: 338 -------------RG--TMTGLALRHMVEHSFSEAQGA---RPRALNVPRVGLVFTDGRS 379
                        RG  T+TG ALR   E  F  A      RPR     RV ++ T+  S
Sbjct: 403 VPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPR-----RVVVLLTESHS 457

Query: 380 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 439
           +D+++  A  A+   +++  VG  +AV AEL EI   P   HV    D   + + +  L+
Sbjct: 458 EDEVAGPARHARARELLLLGVG-SEAVRAELEEITGSPK--HVMVYSDPQDLFNQIPELQ 514

Query: 440 GSICPEE 446
           G +C  +
Sbjct: 515 GKLCSRQ 521



 Score =  112 bits (279), Expect = 1e-24
 Identities = 77/212 (36%), Positives = 109/212 (51%), Gaps = 11/212 (5%)

Query: 262 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 321
           VD++ L+DGS SV   +FE  K F   + D LD+SPE  RVG  QFSS    EFPL  + 
Sbjct: 50  VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109

Query: 322 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 381
           T  EVK  +  + +    T T LAL++++       + A     +VP++ ++ TDG+SQ 
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164

Query: 382 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH-LLENLRG 440
           D+++ + + KE G+ ++AVGV      EL  +ASEP   HV  A      T+ L   L  
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224

Query: 441 S-ICPEEGISAGTELRSPCE---CESLVEFQG 468
           S IC         E   PCE    E + EF G
Sbjct: 225 SAICSSATPDCRVEAH-PCEHRTLEMVREFAG 255



 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 3/162 (1%)

Query: 26  PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
           P C T  LDLVF++D+S SV P  F  M+ F+        V P+ T+VG++ Y SQVQ+ 
Sbjct: 523 PGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTA 582

Query: 86  FPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIV 145
           F L     R  M RAI     L      G A+ +  +   +V  GARP    VP+  V++
Sbjct: 583 FGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP---GVPKAVVVL 639

Query: 146 TDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASP 187
           T GR  +  A  A + R  GI +  VGV       LR +A P
Sbjct: 640 TGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGP 681


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score =  131 bits (329), Expect = 2e-30
 Identities = 64/181 (35%), Positives = 112/181 (61%), Gaps = 3/181 (1%)

Query: 263  DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
            D+VLLVDGS S+   NF  V+ F+++IV+  D+ P+  ++ L Q+S   RTE+ L  +  
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258

Query: 323  AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
               + QAV  + Y    T+TG+AL  + + +F    G RPRA    ++G++ TDG+SQDD
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA---RKIGVLITDGKSQDD 1315

Query: 383  ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
            +   + + K+EG+ ++A+G+  A E EL+ IA++P + H     DF +++ ++++L  ++
Sbjct: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375

Query: 443  C 443
            C
Sbjct: 1376 C 1376



 Score =  126 bits (316), Expect = 5e-29
 Identities = 66/181 (36%), Positives = 108/181 (59%), Gaps = 3/181 (1%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           DLV LVDGS SV   NF+ +  F+  +V   D+  E TRVG+VQ+SS  RTEF L +Y  
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199

Query: 323 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             E+  A+  + Y    TMTG A+ ++V+++F+E+ GAR   +  P+V ++ TDG+SQD+
Sbjct: 200 RDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR---VGFPKVAIIITDGKSQDE 256

Query: 383 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
           + + A   +  G+ ++++G+  A   EL++IAS P+  HV    +F  +  +   +   +
Sbjct: 257 VEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQV 316

Query: 443 C 443
           C
Sbjct: 317 C 317



 Score =  124 bits (310), Expect = 3e-28
 Identities = 74/209 (35%), Positives = 120/209 (57%), Gaps = 11/209 (5%)

Query: 15  QPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG 74
           +P +T++Q       T   DLVF++D S SV    F+ +  F+  L+   ++G   TRVG
Sbjct: 124 KPGKTEIQKCSVSAWT---DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180

Query: 75  VIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPP 134
           V+QYSS  ++ F L  + +R+++  AI+ +      TMTG AI Y +   F+ + GAR  
Sbjct: 181 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR-- 238

Query: 135 EERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVF 194
               P+VA+I+TDG+ QD V   A + R  G+E++++G++ AD   L+ +AS P   HVF
Sbjct: 239 -VGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVF 297

Query: 195 LVESFDLIQEFGLQFQSRLCVRDLCNGVD 223
            V +FD I    +  Q+ + +  +C+GVD
Sbjct: 298 NVANFDAI----VDIQNEI-ISQVCSGVD 321



 Score =  119 bits (299), Expect = 5e-27
 Identities = 68/205 (33%), Positives = 107/205 (52%), Gaps = 11/205 (5%)

Query: 15  QPWETQLQLTGPRCHTG---PLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
           QP + Q++     C  G     D+VF++D S S+    F  +R FL  L++   + PN  
Sbjct: 423 QPMKVQVE-----CSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRV 477

Query: 72  RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGA 131
           ++ ++QYS    + F L+ F++ ED+  AI         T TG A+ Y     F  ++G+
Sbjct: 478 QISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGS 537

Query: 132 RPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDE 191
           R     VP+V +++TDG+  D   + A + R   +EI+AVGV+ A    L A+ASPP + 
Sbjct: 538 R---SNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAET 594

Query: 192 HVFLVESFDLIQEFGLQFQSRLCVR 216
           HVF VE FD  Q    +    +C+R
Sbjct: 595 HVFTVEDFDAFQRISFELTQSICLR 619



 Score =  114 bits (284), Expect = 3e-25
 Identities = 67/190 (35%), Positives = 102/190 (53%), Gaps = 3/190 (1%)

Query: 254 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 313
           C+R  +   D+V LVDGS S+   NF  V+ F+  +V   ++SP   ++ LVQ+S    T
Sbjct: 431 CSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHT 490

Query: 314 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 373
           EF L ++    ++ +A+    Y    T TG A+ ++ E  F  ++G+R    NVP+V ++
Sbjct: 491 EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRS---NVPKVMIL 547

Query: 374 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 433
            TDG+S D     A + +   + ++AVGV  AV +EL  IAS PAE HV    DF     
Sbjct: 548 ITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQR 607

Query: 434 LLENLRGSIC 443
           +   L  SIC
Sbjct: 608 ISFELTQSIC 617



 Score =  110 bits (274), Expect = 4e-24
 Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)

Query: 257  CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 315
            C+    D+V L D S S+   NF  V +F+ N +  F ++SP G +V  VQ+S  V++EF
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376

Query: 316  PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 375
             L  Y   A    A+  + Y    T TG AL  + E   +   G R    NVP+V +V T
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 2433

Query: 376  DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 435
            DGRSQD++   A   ++ G  ++ VGV      EL  IAS+P+E HV    DF +   + 
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 2493

Query: 436  ENLRGSIC 443
            +NL   +C
Sbjct: 2494 DNLITFVC 2501



 Score = 99.0 bits (245), Expect = 9e-21
 Identities = 52/192 (27%), Positives = 99/192 (51%), Gaps = 4/192 (2%)

Query: 24   TGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQV 82
            +G  C T    D+V ++D S S+    F T+R F+  ++   ++GP   ++ + QYS   
Sbjct: 1188 SGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDP 1247

Query: 83   QSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVA 142
            ++ + L A   ++ + +A+ +L      T+TG+A+ +     F    G RP   R  ++ 
Sbjct: 1248 RTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---RARKIG 1304

Query: 143  VIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLI 202
            V++TDG+ QD V   + + +  G+E++A+G++ AD   L+ +A+ P D H + V  F+ +
Sbjct: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364

Query: 203  QEFGLQFQSRLC 214
                      LC
Sbjct: 1365 SRIVDDLTINLC 1376



 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)

Query: 28   CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
            C     D+VF+ D+S S+    F  + +F+   + G + + P   +V  +QYS +V+S F
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376

Query: 87   PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
             L  ++ +     A++++      T TG A+ +      +   G R   + VP+V V+VT
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 2433

Query: 147  DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
            DGR QD V + A   +  G  ++ VGV   D   L  +AS P + HVF+V+ F+  ++
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 2491


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score =  129 bits (323), Expect = 8e-30
 Identities = 69/200 (34%), Positives = 119/200 (59%), Gaps = 7/200 (3%)

Query: 247 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 306
           L  DG+  + CR    DLV ++DGS SV P+NFE+VK+++  I    D+ P+  +VG+VQ
Sbjct: 21  LAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQ 80

Query: 307 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 366
           +S     E PLG Y +   +  AV ++ Y+   T TG A++  +++ F+++      +  
Sbjct: 81  YSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKS------SRF 134

Query: 367 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAELHVSYA 425
           + ++ +V TDG+SQDD+   A  A++  I ++A+GVG   E AELR IA++P+  +V Y 
Sbjct: 135 LTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYV 194

Query: 426 PDFGTMTHLLENLRGSICPE 445
            D+  ++ + E ++  +C E
Sbjct: 195 EDYIAISKIREVMKQKLCEE 214



 Score =  120 bits (302), Expect = 2e-27
 Identities = 69/216 (31%), Positives = 115/216 (53%), Gaps = 7/216 (3%)

Query: 5   LCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
           LC  ++LLL      +       C T P DLVF++D S SV P  FE ++++L+ + +  
Sbjct: 8   LCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNF 67

Query: 65  NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVA 124
           ++GP   +VGV+QYS       PL ++   E +  A+  ++ L   T TG AIQ+A++  
Sbjct: 68  DIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYL 127

Query: 125 FSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGV-QRADVGSLRA 183
           F+ +         + ++AV++TDG+ QD V + A  AR   I ++A+GV    +   LRA
Sbjct: 128 FAKS------SRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRA 181

Query: 184 MASPPLDEHVFLVESFDLIQEFGLQFQSRLCVRDLC 219
           +A+ P   +VF VE +  I +     + +LC   +C
Sbjct: 182 IANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVC 217


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score =  118 bits (295), Expect = 1e-26
 Identities = 76/223 (34%), Positives = 117/223 (52%), Gaps = 5/223 (2%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           D+V LVDGS S+   +F+ VK F+  ++   ++ P+  +VGL Q+S   +TE+ L    T
Sbjct: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238

Query: 323 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
             +V  AV  + Y    T TGLAL H++  +   A G RP A    +V ++ TDG+SQDD
Sbjct: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEA---AKVVILVTDGKSQDD 295

Query: 383 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
           +   A   K+ G+ ++AVGV  A EAELR +AS P ++ V    DF  +  L   L   I
Sbjct: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355

Query: 443 CPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLT 485
           C  + +  G+  + P    +L      T   L  +T +  +L+
Sbjct: 356 C--QRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLS 396



 Score =  107 bits (268), Expect = 2e-23
 Identities = 59/168 (35%), Positives = 91/168 (54%), Gaps = 3/168 (1%)

Query: 32  PLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAF 91
           P D+VF++D S S+    F+ ++ FL  ++    +GP+  +VG+ QYS   Q+ + L + 
Sbjct: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
           S +E +  A+R L      T TGLA+ + +      A G RP      +V ++VTDG+ Q
Sbjct: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP---EAAKVVILVTDGKSQ 293

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
           D V   A   +  G+ ++AVGV+ AD   LR +ASPP D  V  V  F
Sbjct: 294 DDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDF 341


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  108 bits (269), Expect = 1e-23
 Identities = 70/208 (33%), Positives = 105/208 (50%), Gaps = 8/208 (3%)

Query: 242 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD--VSPEG 299
           P  R    +  +C R      D+V L+DGS S+   NF  V+ F+  +V       S +G
Sbjct: 19  PRVRAQHRERVTCTRLYAA--DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQG 76

Query: 300 TRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQG 359
            R   VQ+S   RTEF L   G+  +V +A+  + Y    T TG A+ H+ +H F   Q 
Sbjct: 77  VRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLP-QL 135

Query: 360 ARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAE 419
           ARP    VP+V ++ TDG+SQD +   A R K +G+ ++AVG+  A   EL+ +AS+P  
Sbjct: 136 ARP---GVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTS 192

Query: 420 LHVSYAPDFGTMTHLLENLRGSICPEEG 447
               +  DF  +  LL  +   +C   G
Sbjct: 193 DFFFFVNDFSILRTLLPLVSRRVCTTAG 220



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 6/183 (3%)

Query: 34  DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA--TRVGVIQYSSQVQSVFPLRAF 91
           D+VF++D S S+    F  +R FL GL+   +   +A   R   +QYS   ++ F L A 
Sbjct: 38  DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 92  SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
               D+ RAIR+L      T TG AI +  +  F + + ARP    VP+V +++TDG+ Q
Sbjct: 98  GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVF-LPQLARPG---VPKVCILITDGKSQ 153

Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
           D V   A + + +G++++AVG++ AD   L+ +AS P  +  F V  F +++        
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213

Query: 212 RLC 214
           R+C
Sbjct: 214 RVC 216



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 46/167 (27%), Positives = 79/167 (47%), Gaps = 6/167 (3%)

Query: 26   PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQS 84
            P C  G  D+VF+  +++       E  R+ L  L+  L  +GP A +VG++ YS +   
Sbjct: 1046 PVCPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSP 1104

Query: 85   VFPLRAFSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
            +FPL        + + IRD+  +   G   G A+  A    + +A  A    + VP V V
Sbjct: 1105 LFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHR--YMLAPDAPGRRQHVPGVMV 1162

Query: 144  IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
            ++ D   +  +     +A+A G+ +  +G+  AD   LR +A P +D
Sbjct: 1163 LLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA-PGMD 1208



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 6/190 (3%)

Query: 257  CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 315
            C  G  D+V L   ++       E  +R + ++V  L  + P+  +VGL+ +S R    F
Sbjct: 1048 CPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLF 1106

Query: 316  PLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 374
            PL        + Q +  + YM+  G   G A+  +  H +  A  A  R  +VP V ++ 
Sbjct: 1107 PLNGSHDLGIILQRIRDMPYMDPSGNNLGTAV--VTAHRYMLAPDAPGRRQHVPGVMVLL 1164

Query: 375  TDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG-TMTH 433
             D   + DI      A+  G+ +  +G+  A   +LR +A     +   +A D G ++  
Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224

Query: 434  LLENLRGSIC 443
             +  L  ++C
Sbjct: 1225 AVSGLATALC 1234


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  107 bits (267), Expect = 3e-23
 Identities = 98/401 (24%), Positives = 178/401 (44%), Gaps = 53/401 (13%)

Query: 25   GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
            GP+ ++  LD+ FV++ S  +   +F   ++F+  +++ ++VG ++  V V+QYS  V  
Sbjct: 1489 GPKRNSMVLDVAFVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTV 1548

Query: 85   VFPLRAFSRREDMERAIRDLVPLAQG---TMTGLAIQYAMNVAFSVAEGARPPEERVPRV 141
             +P      + D+ + +R++    QG   T TGLA++Y  + +F V++G R   E+ P +
Sbjct: 1549 EYPFSEAQSKGDILQRVREI--RYQGGNRTNTGLALRYLSDHSFLVSQGDR---EQAPNL 1603

Query: 142  AVIVTDGRPQDRVAEVAAQARARGIEIYAVGV-QRADVGSLRAMASPPLDEHVFLVESFD 200
              +VT     D +  +        I++  +GV   A+V  L  +  P       L++ F+
Sbjct: 1604 VYMVTGNPASDEIKRLPGD-----IQVVPIGVGPNANVQELERIGWPNAP---ILIQDFE 1655

Query: 201  LIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREG 260
             +         + C               C  EGL    L P           C++    
Sbjct: 1656 TLPREAPDLVLQRC---------------CSGEGLQIPTLSP--------APDCSQ---- 1688

Query: 261  HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 320
             +D++LL+DGS S     F+ +K F    +   ++ P  T+V ++Q+ S    + P   +
Sbjct: 1689 PLDVILLLDGSSSFPASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITTIDVP---W 1745

Query: 321  GTAAEVKQAVLAVEYMER---GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 377
                E    +  V+ M+R    +  G AL   V +  SE  GARP A     V ++ TD 
Sbjct: 1746 NVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVRYLTSEMHGARPGASKA--VVILVTD- 1802

Query: 378  RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA 418
             S D +   A  A+   + ++ +G+G   +A    I + PA
Sbjct: 1803 VSVDSVDAAADAARSNRVTVFPIGIGDRYDAAQLRILAGPA 1843



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 99/432 (22%), Positives = 184/432 (42%), Gaps = 30/432 (6%)

Query: 33   LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
            LDLVF++D S  +   EFE ++ F++ ++  L +     RV V++Y     +   L+   
Sbjct: 1276 LDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRK 1335

Query: 93   RREDMERAIRDLVPLA--QGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRP 150
            R  ++ R I   V  A  Q   T   ++Y +   FS  +  RP   R+  + +   + + 
Sbjct: 1336 RPSELRR-IASQVKYAGSQVASTSEVLKYTLFQIFSKID--RPEASRITLLLMASQEPQR 1392

Query: 151  QDR-VAEVAAQARARGIEIYAVGV-QRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
              R         + + + +  VG+   A++  +R +     +   F++ S D +++   +
Sbjct: 1393 MSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVLSSVDELEQQRDE 1452

Query: 209  FQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV 268
              S LC  DL            +   ++   + P    +   G   N      +D+  ++
Sbjct: 1453 IVSYLC--DLAPEAPP----PTLPPDMAQVTVGPGLLGVSTLGPKRNSM---VLDVAFVL 1503

Query: 269  DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQ 328
            +GS  +   +F   K F+ +++  +DV  +   V ++Q+S  V  E+P     +  ++ Q
Sbjct: 1504 EGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGDILQ 1563

Query: 329  AVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWA 387
             V  + Y     T TGLALR++ +HSF  +QG R +A   P +  + T   + D+I    
Sbjct: 1564 RVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQA---PNLVYMVTGNPASDEI---- 1616

Query: 388  ARAKEEGIVMYAVGVG-KAVEAELREIASEPAELHVSYAPDFGTMTHLLENL-RGSICPE 445
             +     I +  +GVG  A   EL  I    A + +    DF T+     +L     C  
Sbjct: 1617 -KRLPGDIQVVPIGVGPNANVQELERIGWPNAPILIQ---DFETLPREAPDLVLQRCCSG 1672

Query: 446  EGISAGTELRSP 457
            EG+   T   +P
Sbjct: 1673 EGLQIPTLSPAP 1684


>gi|40068485 von Willebrand factor A domain containing 1 isoform 1
           [Homo sapiens]
          Length = 445

 Score =  102 bits (255), Expect = 6e-22
 Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)

Query: 263 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 322
           DL+ L+D S SV    F  V+ FV Q+V  L +     R  LV   SR  TEFP G++ +
Sbjct: 34  DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93

Query: 323 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 382
               + AV A       T TGLAL +  E  F+EA GARP    VP+V +  TDG S D 
Sbjct: 94  GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150

Query: 383 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 442
           +       K+ G+ ++ V  G+    EL   AS PAE H+ +  D   +  +++ LRGSI
Sbjct: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209



 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)

Query: 25  GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
           GP       DL+F++DSS SV  +EF  +R+F+  L+  L +G  A R  ++   S+  +
Sbjct: 25  GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84

Query: 85  VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
            FP    S  E  + A+R        T TGLA+ YA    F+ A GARP    VP+V V 
Sbjct: 85  EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141

Query: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
           VTDG   D V     + +  G+ ++ V   R +   L A AS P ++H+  V+  DL
Sbjct: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 99.0 bits (245), Expect = 9e-21
 Identities = 63/197 (31%), Positives = 109/197 (55%), Gaps = 20/197 (10%)

Query: 19  TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQY 78
           T++   GP+C   PL+LVFVIDSS SV P  F+ ++ F+  +   + +     R+G+I Y
Sbjct: 783 TEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINY 842

Query: 79  SSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERV 138
           S +V+ V  L+ FS ++D + A+ ++  L +GT T  A+Q     A  + E ARP    V
Sbjct: 843 SHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQ----AANDMFEDARP---GV 895

Query: 139 PRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGS-------LRAMASP 187
            +VA+++TDG    R ++++ EV   A    +EI+ +GV + +  +       +  +A+ 
Sbjct: 896 KKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATD 955

Query: 188 PLDEHVFLVESFDLIQE 204
           P  EHV+  + F  +Q+
Sbjct: 956 P--EHVYQFDDFFTLQD 970



 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 57/202 (28%), Positives = 102/202 (50%), Gaps = 21/202 (10%)

Query: 256 RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEF 315
           +C+E  ++LV ++D S+SV P+NF+++K FV  + D + +     R+G++ +S +V    
Sbjct: 791 KCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVA 850

Query: 316 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 375
            L ++ +  + K AV  ++Y+  GT T  AL    + +    + ARP    V +V LV T
Sbjct: 851 NLKQFSSKDDFKLAVDNMQYLGEGTYTATAL----QAANDMFEDARP---GVKKVALVIT 903

Query: 376 DG----RSQDDISVWAARAKEEGIVMYAVGVGK-------AVEAELREIASEPAELHVSY 424
           DG    R ++ ++     A +  + ++ +GV K           E+  IA++P   HV  
Sbjct: 904 DGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPE--HVYQ 961

Query: 425 APDFGTMTHLL-ENLRGSICPE 445
             DF T+   L + L   IC +
Sbjct: 962 FDDFFTLQDTLKQKLFQKICED 983



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 43/201 (21%), Positives = 88/201 (43%), Gaps = 21/201 (10%)

Query: 33  LDLVFVIDSSRSVRPFEFETMRQFLMGL---LRGLNVGPNA---TRVGVIQYSSQVQSVF 86
           +D+VF++DSS S +   F+  + F+  L   +  L  G +     ++  +Q+SS VQ   
Sbjct: 47  IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106

Query: 87  PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
           P  ++   +  ++ ++ +  + QGT +  AI  A  +        R   +   +V +++T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLL------KREGRKDGVKVVLLMT 160

Query: 147 DGRPQDR---VAEVAAQARARGIEIYAVGVQR-ADVGSLRAMASPPLDEHVFLVESFDLI 202
           DG    +   V  ++  AR  GI    + +    +   LR ++     E   L+    L+
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLV 220

Query: 203 QE----FGLQFQSRLCVRDLC 219
            +      + F+ + C R +C
Sbjct: 221 DKIQDRLDILFEKK-CERKIC 240



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 16/165 (9%)

Query: 262 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSRVRTEF 315
           +D+V +VD S+S +   F+  K FV+ + D +     G       ++  +QFSS V+ + 
Sbjct: 47  IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106

Query: 316 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 375
           P   +      KQ V ++  + +GT +  A+ +       + +G +       +V L+ T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATR--LLKREGRKDGV----KVVLLMT 160

Query: 376 DG---RSQDDISVWAARAKEEGIVMYAVGVGKAV-EAELREIASE 416
           DG       D+   +  A+  GI    + +   V EA+LR I+ +
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGD 205


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 117/438 (26%), Positives = 193/438 (44%), Gaps = 89/438 (20%)

Query: 28  CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN------VGPNATRVGVIQYS-S 80
           C  GP+DL+FV+DSS S+    FE  + F++ ++  L+        P  +  GV+QYS S
Sbjct: 609 CKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQYSHS 668

Query: 81  QVQSVFPLRAFSRR--EDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERV 138
           Q+Q    LR+ S R  ++++ AI+ L  +A GT TG A+QY  +          PP    
Sbjct: 669 QMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLL-------PPSPN- 720

Query: 139 PRVAVIVTDGRPQ-DRVAEVAAQARARGIEIYAVGVQ----------RADVGSLRAMASP 187
            R+A+++TDGR    R         + GI++ +VG++          + +V S + +A  
Sbjct: 721 NRIALVITDGRSDTQRDTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPS 780

Query: 188 PLDEHVFLVES--FDLIQE-FGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEG 244
                + LV+    +L+++ F     +++C+   C   D+ C     S            
Sbjct: 781 QGRPGLSLVKENYAELLEDAFLKNVTAQICIDKKC--PDYTCPITFSSP----------- 827

Query: 245 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVD-FLDVS----PEG 299
                             D+ +L+DGS SV   NF+  KRF  ++ + FL          
Sbjct: 828 -----------------ADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD 870

Query: 300 TRVGLVQFS-------SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEH 352
            RV +VQ+S        R   +F L  Y   A    AV A++++   T    AL ++   
Sbjct: 871 VRVAVVQYSGTGQQRPERASLQF-LQNYTALA---SAVDAMDFINDATDVNDALGYVTRF 926

Query: 353 SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEE----GIVMYAVGVGKAV-E 407
               + GA  + L      L+F+DG SQ        +A +E    GI ++ V VG+ V E
Sbjct: 927 YREASSGAAKKRL------LLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGRQVNE 980

Query: 408 AELRE-IASEPAELHVSY 424
             +R  +  + AE  V+Y
Sbjct: 981 PHIRVLVTGKTAEYDVAY 998



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 46/136 (33%), Positives = 71/136 (52%), Gaps = 17/136 (12%)

Query: 253 SCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD------VSPEGTRVGLVQ 306
           SC  C+ G +DL+ ++D S+S+  QNFE+ K FV +++D L         P  +  G+VQ
Sbjct: 605 SCCECKCGPIDLLFVLDSSESIGLQNFEIAKDFVVKVIDRLSRDELVKFEPGQSYAGVVQ 664

Query: 307 FSSRVRTEFPLGR---YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 363
           +S     E    R        E+K+A+ ++++M  GT TG AL+      ++  Q   P 
Sbjct: 665 YSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQ------YTRDQLLPPS 718

Query: 364 ALNVPRVGLVFTDGRS 379
             N  R+ LV TDGRS
Sbjct: 719 PNN--RIALVITDGRS 732



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 40/164 (24%), Positives = 65/164 (39%), Gaps = 18/164 (10%)

Query: 24  TGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLL-RGLNVG----PNATRVGVIQY 78
           T P   + P D+  ++D S SV    F+T ++F   L  R L  G     +  RV V+QY
Sbjct: 819 TCPITFSSPADITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHDVRVAVVQY 878

Query: 79  S---SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPE 135
           S    Q      L+       +  A+  +  +   T    A+ Y        + GA    
Sbjct: 879 SGTGQQRPERASLQFLQNYTALASAVDAMDFINDATDVNDALGYVTRFYREASSGA---- 934

Query: 136 ERVPRVAVIVTDGRPQD----RVAEVAAQARARGIEIYAVGVQR 175
               +  ++ +DG  Q      + +   +A+  GIEI+ V V R
Sbjct: 935 --AKKRLLLFSDGNSQGATPAAIEKAVQEAQRAGIEIFVVVVGR 976



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 38/165 (23%), Positives = 75/165 (45%), Gaps = 31/165 (18%)

Query: 32  PLDLVFVIDSSRSV----RPFE--FETMRQFLMGLLRGL---------NVGPNATRVGVI 76
           P+DL FV+D+S SV    +P+    + ++ F    +  L         N+  NA   G +
Sbjct: 35  PVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNA---GAL 91

Query: 77  QYSSQVQSVFPL-RAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPE 135
            YS +V+ +  L R    R+ ++ ++  +    +GT T  AI+  +     +  G+   E
Sbjct: 92  HYSDEVEIIQGLTRMPGGRDALKSSVDAVKYFGKGTYTDCAIKKGLEQL--LVGGSHLKE 149

Query: 136 ERVPRVAVIVTDGRPQDRVAE-------VAAQARARGIEIYAVGV 173
               +  ++VTDG P +   E          +A+  G+++++V +
Sbjct: 150 N---KYLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAI 191


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 69/239 (28%), Positives = 112/239 (46%), Gaps = 18/239 (7%)

Query: 253 SCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVR 312
           S   C     D+V L+DGS S+  +NF  +  FV  ++         T+  L+QFS++ +
Sbjct: 141 SRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVIS--QFQRPSTQFSLMQFSNKFQ 198

Query: 313 TEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGL 372
           T F    +  ++     + +V  ++  T T  A++++V   F  + GAR  A    ++ +
Sbjct: 199 THFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDA---AKILI 255

Query: 373 VFTDGRSQDDISVW---AARAKEEGIVMYAVGVGKAVE-----AELREIASEPAELHVSY 424
           V TDG+ + D   +      A   GI+ YA+GVG A +      EL +IAS+P++ H+  
Sbjct: 256 VITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFK 315

Query: 425 APDFGTMTHLLENLRGSICPEEGI----SAGTELRSPCECESLV-EFQGRTLGALESLT 478
             DF  +  +   L+  I   EG     S+  EL    E  S V    G  LGA+ S T
Sbjct: 316 VEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGPVLGAVGSFT 374



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 68/253 (26%), Positives = 112/253 (44%), Gaps = 17/253 (6%)

Query: 10  LLLLLQPWET--QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG 67
           L  LL P +   +L ++   C     D+VF+ID S S+    F TM  F+  ++      
Sbjct: 125 LCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ-- 182

Query: 68  PNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSV 127
             +T+  ++Q+S++ Q+ F    F R  +    +  +  L   T T  AIQ  ++  F  
Sbjct: 183 RPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHA 242

Query: 128 AEGARPPEERVPRVAVIVTDGRPQDR---VAEVAAQARARGIEIYAVGV-----QRADVG 179
           + GAR       ++ +++TDG+ +       +V   A A GI  YA+GV      R    
Sbjct: 243 SYGAR---RDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWK 299

Query: 180 SLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL-CVRDLCNGVDHGCEFQCVSEGLSYR 238
            L  +AS P  EH+F VE FD +++   Q + ++  +           E +   EG S  
Sbjct: 300 ELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFS-A 358

Query: 239 CLCPEGRQLQADG 251
              P+G  L A G
Sbjct: 359 VFTPDGPVLGAVG 371


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,447,745
Number of Sequences: 37866
Number of extensions: 732326
Number of successful extensions: 2776
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1903
Number of HSP's gapped (non-prelim): 690
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.