Guide to the Human Genome
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Name: VWF Sequence: fasta or formatted (2813aa) NCBI GI: 89191868
Description:

von Willebrand factor preproprotein

Referenced in:

Coagulation
Collagen
Mucins
Platelets and Megakaryocytes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4        153           3
 C cysteine            8.3        234           2
 D aspartate           5.6        157           2
 E glutamate           6.5        182           2
 F phenylalanine       3.1         88           2
 G glycine             7.3        206           2
 H histidine           2.5         69           2
 I isoleucine          3.4         95           2
 K lysine              3.8        108           4
 L leucine             8.1        228           3
 M methionine          2.0         56           2
 N asparagine          3.5         98           2
 P proline             6.3        176           3
 Q glutamine           4.7        132           2
 R arginine            5.1        143           2
 S serine              7.4        207           3
 T threonine           5.4        152           4
 V valine              8.0        225           2
 W tryptophan          0.9         26           1
 Y tyrosine            2.8         78           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   von Willebrand factor preproprotein 
MUC5B                 0.126   mucin 5, subtype B, tracheobronchial 
LOC100132635          0.124   PREDICTED: similar to mucin 5, partial 
MUC5AC                0.124   mucin 5AC 
MUC2                  0.122   mucin 2 precursor 
OTOG                  0.106   PREDICTED: otogelin isoform 1 
OTOG                  0.106   PREDICTED: otogelin isoform 2 
OTOG                  0.106   PREDICTED: otogelin isoform 2 
OTOG                  0.106   PREDICTED: otogelin isoform 1 
OTOG                  0.106   PREDICTED: otogelin isoform 2 
OTOG                  0.106   PREDICTED: otogelin isoform 1 
SSPO                  0.101   SCO-spondin 
C12orf64              0.093   PREDICTED: chromosome 12 open reading frame 64 [Hom...
C12orf64              0.093   PREDICTED: chromosome 12 open reading frame 64 [Hom...
C12orf64              0.093   PREDICTED: hypothetical protein LOC283310 
LOC100294420          0.091   PREDICTED: similar to mucin 2 
MUC6                  0.089   mucin 6, gastric 
LOC100291118          0.082   PREDICTED: hypothetical protein XP_002347351 
LOC100287737          0.082   PREDICTED: hypothetical protein XP_002343203 
LOC100293676          0.049   PREDICTED: similar to Fc fragment of IgG binding pr...
LOC100290309          0.049   PREDICTED: hypothetical protein XP_002348012 
FCGBP                 0.049   Fc fragment of IgG binding protein 
LOC100133944          0.047   PREDICTED: similar to Fc fragment of IgG binding pr...
ZAN                   0.045   zonadhesin isoform 3 
ZAN                   0.045   zonadhesin isoform 6 
TECTA                 0.041   tectorin alpha precursor 
LOC100293409          0.038   PREDICTED: similar to Mucin-19 
KCP                   0.034   cysteine rich BMP regulator 2 isoform 1 
LOC100293983          0.030   PREDICTED: similar to mucin, partial 
LOC100293643          0.028   PREDICTED: similar to Fc fragment of IgG binding pr...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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