Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13699834
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
(540 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 1084 0.0
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 1064 0.0
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 967 0.0
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 445 e-125
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 309 5e-84
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 299 4e-81
gi|11321565 matrilin 3 precursor [Homo sapiens] 273 2e-73
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 212 6e-55
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 168 1e-41
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 149 6e-36
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 137 2e-32
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 137 2e-32
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 137 2e-32
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 134 2e-31
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 134 3e-31
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 129 9e-30
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 118 1e-26
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 118 2e-26
gi|21359974 vitrin [Homo sapiens] 110 2e-24
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 109 6e-24
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 108 2e-23
gi|205277471 cochlin precursor [Homo sapiens] 103 5e-22
gi|4758022 cochlin precursor [Homo sapiens] 103 5e-22
gi|40068485 von Willebrand factor A domain containing 1 isoform ... 102 7e-22
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 99 1e-20
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 96 8e-20
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ... 96 8e-20
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 94 2e-19
gi|34452173 integrin alpha X precursor [Homo sapiens] 88 2e-17
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 85 2e-16
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 1084 bits (2803), Expect = 0.0
Identities = 540/540 (100%), Positives = 540/540 (100%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH 240
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH 240
Query: 241 CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 300
CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE
Sbjct: 241 CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 300
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR
Sbjct: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
Query: 361 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420
YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS
Sbjct: 361 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420
Query: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480
QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR
Sbjct: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480
Query: 481 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540
GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 481 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 1064 bits (2751), Expect = 0.0
Identities = 540/581 (92%), Positives = 540/581 (92%), Gaps = 41/581 (7%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAID----------------------- 217
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAID
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH 240
Query: 218 ------------------YCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 259
YCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL
Sbjct: 241 CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 300
Query: 260 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 319
CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN
Sbjct: 301 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN 360
Query: 320 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 379
FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER
Sbjct: 361 FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER 420
Query: 380 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 439
GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY
Sbjct: 421 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 480
Query: 440 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 499
AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC
Sbjct: 481 AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC 540
Query: 500 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540
ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 541 ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 581
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 967 bits (2500), Expect = 0.0
Identities = 499/540 (92%), Positives = 499/540 (92%), Gaps = 41/540 (7%)
Query: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL
Sbjct: 1 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL 60
Query: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA
Sbjct: 61 LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA 120
Query: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS
Sbjct: 121 MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS 180
Query: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH 240
LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC
Sbjct: 181 LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-------------------------- 214
Query: 241 CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 300
VRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE
Sbjct: 215 ---------------VRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE 259
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR
Sbjct: 260 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 319
Query: 361 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420
YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS
Sbjct: 320 YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 379
Query: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480
QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR
Sbjct: 380 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 439
Query: 481 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 540
GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK
Sbjct: 440 GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK 499
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 445 bits (1145), Expect = e-125
Identities = 252/532 (47%), Positives = 330/532 (62%), Gaps = 59/532 (11%)
Query: 10 LLLLLQPWETQ---LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNV 66
LLLLLQ + Q G C T P DLVFV+DSSRSVRP EFE ++ FL ++ L+V
Sbjct: 14 LLLLLQALCSPGLAPQSRGHLCRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDV 73
Query: 67 GPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFS 126
GPNATRVG++ Y+S V+ F LRA + + +A+R + PL+ GTMTGLAIQ+A+ AF
Sbjct: 74 GPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFG 133
Query: 127 VAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
AEG R + +V ++VTDGRPQD V +V+A+ARA G+E++A+GV D +LR +AS
Sbjct: 134 DAEGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGVGSVDKATLRQIAS 193
Query: 187 PPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHD 246
P DEHV VES+ +I++ +FQ C +
Sbjct: 194 EPQDEHVDYVESYSVIEKLSRKFQEAFCVVS----------------------------- 224
Query: 247 LQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGH---- 302
DLC DH CE C+S SY C C EG L +DGK+CN C G
Sbjct: 225 -----------DLCATGDHDCEQVCISSPGSYTCACHEGFTLNSDGKTCNVCSGGGGSSA 273
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
DLV L+DGSKSVRP+NFELVK+F++QIVD LDVS + +VGLVQ+SS VR EFPLGR+
Sbjct: 274 TDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFH 333
Query: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
T ++K AV + YME+GTMTG AL++++++SF+ + GARP A +VG+VFTDGRSQD
Sbjct: 334 TKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGA---QKVGIVFTDGRSQD 390
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 482
I+ A +AK+ G M+AVGVG AVE ELREIASEP H Y DF T+ + + L+
Sbjct: 391 YINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAEHYFYTADFKTINQIGKKLQKK 450
Query: 483 ICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLEN 534
IC EE PC CESLV+FQ + G L++LT L ++ RL LEN
Sbjct: 451 ICVEE---------DPCACESLVKFQAKVEGLLQALTRKLEAVSKRLAILEN 493
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 309 bits (791), Expect = 5e-84
Identities = 157/367 (42%), Positives = 216/367 (58%), Gaps = 47/367 (12%)
Query: 217 DYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL 276
D C +H C+H CV++ C C EG L DG+ C+ +D+C HGCE CV+ G
Sbjct: 568 DVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGN 627
Query: 277 SYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDV 336
SY C C EG L DG+ C +C EG +DLV ++DGSKS+ +NFE+VK+FV I+D L +
Sbjct: 628 SYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTI 687
Query: 337 SPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS 396
SP+ RVGL+Q+S++V TEF L + +A ++K+AV ++YM +G+MTGLAL+HM E SF+
Sbjct: 688 SPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFT 747
Query: 397 EAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIAS 456
+ +GARP + VPR +VFTDGR+QDD+S WA++AK GI MYAVGVGKA+E EL+EIAS
Sbjct: 748 QGEGARPLSTRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIAS 807
Query: 457 EPAELHVSYAPDFGTMTHLLENLRGSIC-------------------------------- 484
EP H+ YA DF TM + E L+ IC
Sbjct: 808 EPTNKHLFYAEDFSTMDEISEKLKKGICEALEDSDGRQDSPAGELPKTVQQPTVQHRYLF 867
Query: 485 PEEGISAGT---------------ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARL 529
E+ + T E C+CE+L+ FQ + LT L ++T R+
Sbjct: 868 EEDNLLRSTQKLSHSTKPSGSPLEEKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRM 927
Query: 530 EDLENQL 536
E LEN+L
Sbjct: 928 EALENRL 934
Score = 269 bits (688), Expect = 4e-72
Identities = 131/276 (47%), Positives = 184/276 (66%)
Query: 20 QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
Q L C DLVF+IDSSRSV ++ +++F++ +L+ L++GP+ TRVG++QY
Sbjct: 43 QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
S V++ F L+ F R+ ++ERA++ + L+ GTMTGLAIQYA+N+AFS AEGARP E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
RV +IVTDGRPQD VAEVAA+AR GI I+A+GV + D +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222
Query: 200 DLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 259
I+ FQ +LC CS H+C H C++ PG C C++G+ L D +C+++DL
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Query: 260 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 295
C DH CE CV+ S+ C C G L DGK C
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC 318
Score = 169 bits (427), Expect = 8e-42
Identities = 81/188 (43%), Positives = 126/188 (67%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
+C GP+DLVFVID S+S+ FE ++QF+ G++ L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
LR F+ +DM++A+ + + +G+MTGLA+++ +F+ EGARP RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V+E A++A+A GI +YAVGV +A L+ +AS P ++H+F E F + E
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 828 EKLKKGIC 835
Score = 155 bits (393), Expect = 7e-38
Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C DLV ++D S+SV ++ VK F+ I+ FLD+ P+ TRVGL+Q+ S V+ EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L + +EV++AV + ++ GTMTGLA+++ + +FSEA+GARP NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
GR QD ++ AA+A++ GI+++A+GVG+ L+ I SEP E HV +F + L
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230
Query: 478 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 532
+ +C S L C + + LN Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Score = 91.3 bits (225), Expect = 2e-18
Identities = 38/86 (44%), Positives = 50/86 (58%)
Query: 212 RLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQC 271
R A+DYC+ NH C+HECV+ G C C EG L PD ++C D C +HGC+ +C
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHEC 376
Query: 272 VSEGLSYRCLCPEGRQLQADGKSCNR 297
V+ SY C C +G L D K+C R
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRR 402
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/94 (42%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Query: 205 FGLQFQSRLCA-IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGV 263
F L + C IDYC+ NH CQHECV+T CHC +G L PD ++C+ + C
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 264 DHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 297
GCE +CV+ SY C C G L +GK+C+R
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR 443
Score = 85.9 bits (211), Expect = 9e-17
Identities = 37/82 (45%), Positives = 48/82 (58%)
Query: 216 IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEG 275
+DYC +H C++ CV+ C C EGH L+ DG++C D C DHGCE CVS
Sbjct: 485 VDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSE 544
Query: 276 LSYRCLCPEGRQLQADGKSCNR 297
S+ C C EG L+ DGK+C R
Sbjct: 545 DSFVCQCFEGYILREDGKTCRR 566
Score = 79.3 bits (194), Expect = 8e-15
Identities = 32/80 (40%), Positives = 48/80 (60%)
Query: 216 IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEG 275
+D+C+ +H C+ C++T C C EG + D ++C D C DHGCE+ CV+
Sbjct: 444 VDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMD 503
Query: 276 LSYRCLCPEGRQLQADGKSC 295
S+ C CPEG L++DGK+C
Sbjct: 504 RSFACQCPEGHVLRSDGKTC 523
Score = 78.6 bits (192), Expect = 1e-14
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
Query: 202 IQEFGLQFQSRLCA-IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLC 260
++ F L + C I+YC+ C+HECV+ C C G+ L P+G++C D C
Sbjct: 388 LKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHC 447
Query: 261 NGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 310
DHGCE C++ S+ C C EG + D K+C+R VD LL D
Sbjct: 448 AQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-----VDYCLLSD 492
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 299 bits (766), Expect = 4e-81
Identities = 138/268 (51%), Positives = 187/268 (69%)
Query: 217 DYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGL 276
D C +H C+H CV++ C C EG L DG+ C+ +D+C HGCE CV+ G
Sbjct: 568 DVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGN 627
Query: 277 SYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDV 336
SY C C EG L DG+ C +C EG +DLV ++DGSKS+ +NFE+VK+FV I+D L +
Sbjct: 628 SYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTI 687
Query: 337 SPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS 396
SP+ RVGL+Q+S++V TEF L + +A ++K+AV ++YM +G+MTGLAL+HM E SF+
Sbjct: 688 SPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFT 747
Query: 397 EAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIAS 456
+ +GARP + VPR +VFTDGR+QDD+S WA++AK GI MYAVGVGKA+E EL+EIAS
Sbjct: 748 QGEGARPLSTRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIAS 807
Query: 457 EPAELHVSYAPDFGTMTHLLENLRGSIC 484
EP H+ YA DF TM + E L+ IC
Sbjct: 808 EPTNKHLFYAEDFSTMDEISEKLKKGIC 835
Score = 269 bits (688), Expect = 4e-72
Identities = 131/276 (47%), Positives = 184/276 (66%)
Query: 20 QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYS 79
Q L C DLVF+IDSSRSV ++ +++F++ +L+ L++GP+ TRVG++QY
Sbjct: 43 QTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYG 102
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
S V++ F L+ F R+ ++ERA++ + L+ GTMTGLAIQYA+N+AFS AEGARP E VP
Sbjct: 103 STVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVP 162
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
RV +IVTDGRPQD VAEVAA+AR GI I+A+GV + D +L+++ S P ++HVFLV +F
Sbjct: 163 RVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANF 222
Query: 200 DLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL 259
I+ FQ +LC CS H+C H C++ PG C C++G+ L D +C+++DL
Sbjct: 223 SQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Query: 260 CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSC 295
C DH CE CV+ S+ C C G L DGK C
Sbjct: 283 CAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRC 318
Score = 169 bits (427), Expect = 8e-42
Identities = 81/188 (43%), Positives = 126/188 (67%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
+C GP+DLVFVID S+S+ FE ++QF+ G++ L + P A RVG++QYS+QV + F
Sbjct: 648 KCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEF 707
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
LR F+ +DM++A+ + + +G+MTGLA+++ +F+ EGARP RVPR A++ T
Sbjct: 708 TLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFT 767
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V+E A++A+A GI +YAVGV +A L+ +AS P ++H+F E F + E
Sbjct: 768 DGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEIS 827
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 828 EKLKKGIC 835
Score = 155 bits (393), Expect = 7e-38
Identities = 87/235 (37%), Positives = 133/235 (56%), Gaps = 3/235 (1%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C DLV ++D S+SV ++ VK F+ I+ FLD+ P+ TRVGL+Q+ S V+ EF
Sbjct: 51 CENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFS 110
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L + +EV++AV + ++ GTMTGLA+++ + +FSEA+GARP NVPRV ++ TD
Sbjct: 111 LKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTD 170
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
GR QD ++ AA+A++ GI+++A+GVG+ L+ I SEP E HV +F + L
Sbjct: 171 GRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTS 230
Query: 478 NLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDL 532
+ +C S L C + + LN Q T R++DL
Sbjct: 231 VFQKKLCTAHMCST---LEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDL 282
Score = 91.3 bits (225), Expect = 2e-18
Identities = 38/86 (44%), Positives = 50/86 (58%)
Query: 212 RLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQC 271
R A+DYC+ NH C+HECV+ G C C EG L PD ++C D C +HGC+ +C
Sbjct: 317 RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHEC 376
Query: 272 VSEGLSYRCLCPEGRQLQADGKSCNR 297
V+ SY C C +G L D K+C R
Sbjct: 377 VNTDDSYSCHCLKGFTLNPDKKTCRR 402
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/94 (42%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Query: 205 FGLQFQSRLCA-IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGV 263
F L + C IDYC+ NH CQHECV+T CHC +G L PD ++C+ + C
Sbjct: 350 FALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALN 409
Query: 264 DHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 297
GCE +CV+ SY C C G L +GK+C+R
Sbjct: 410 KPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSR 443
Score = 85.9 bits (211), Expect = 9e-17
Identities = 37/82 (45%), Positives = 48/82 (58%)
Query: 216 IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEG 275
+DYC +H C++ CV+ C C EGH L+ DG++C D C DHGCE CVS
Sbjct: 485 VDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSE 544
Query: 276 LSYRCLCPEGRQLQADGKSCNR 297
S+ C C EG L+ DGK+C R
Sbjct: 545 DSFVCQCFEGYILREDGKTCRR 566
Score = 79.3 bits (194), Expect = 8e-15
Identities = 32/80 (40%), Positives = 48/80 (60%)
Query: 216 IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEG 275
+D+C+ +H C+ C++T C C EG + D ++C D C DHGCE+ CV+
Sbjct: 444 VDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMD 503
Query: 276 LSYRCLCPEGRQLQADGKSC 295
S+ C CPEG L++DGK+C
Sbjct: 504 RSFACQCPEGHVLRSDGKTC 523
Score = 78.6 bits (192), Expect = 1e-14
Identities = 40/110 (36%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
Query: 202 IQEFGLQFQSRLCA-IDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLC 260
++ F L + C I+YC+ C+HECV+ C C G+ L P+G++C D C
Sbjct: 388 LKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHC 447
Query: 261 NGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVD 310
DHGCE C++ S+ C C EG + D K+C+R VD LL D
Sbjct: 448 AQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSR-----VDYCLLSD 492
Score = 37.0 bits (84), Expect = 0.046
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 494 ELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQL 536
E C+CE+L+ FQ + LT L ++T R+E LEN+L
Sbjct: 911 EKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRL 953
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 273 bits (699), Expect = 2e-73
Identities = 134/271 (49%), Positives = 186/271 (68%), Gaps = 2/271 (0%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C + PLDLVF+IDSSRSVRP EF ++ F+ ++ L++GP TRV V+ Y+S V+ F
Sbjct: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L+A++ ++ +++A+ + PL+ GTM+GLAIQ AM+ AF+V GAR P +P+VA+IVTD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
GRPQD+V EVAA+A+A GIE+YAVGV RAD+ SL+ MAS PL+EHVF VE++ +I++
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
Query: 208 QFQSRLCAIDYCSFGNHSCQHECVST-PGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHG 266
+FQ CA+D C G H CQH C+S G C C +G+ L D ++C D C HG
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALNTHG 316
Query: 267 CEFQCVSE-GLSYRCLCPEGRQLQADGKSCN 296
CE CV++ SY C C EG L D K+C+
Sbjct: 317 CEHICVNDRSGSYHCECYEGYTLNEDRKTCS 347
Score = 158 bits (400), Expect = 1e-38
Identities = 89/237 (37%), Positives = 133/237 (56%), Gaps = 13/237 (5%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C+ +DLV ++D S+SVRP F VK FV++I+D LD+ P TRV +V ++S V+ EF
Sbjct: 77 CKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L Y +KQAV + + GTM+GLA++ ++ +F+ GAR + N+P+V ++ TD
Sbjct: 137 LQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTD 196
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
GR QD ++ AARA+ GI +YAVGV +A A L+ +ASEP E HV Y +G + L
Sbjct: 197 GRPQDQVNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSS 256
Query: 478 NLRGSICPEEGISAGT-----------ELRSPCECES--LVEFQGRTLGALESLTLN 521
+ + C + GT E + CEC + +T AL+ LN
Sbjct: 257 RFQETFCALDPCVLGTHQCQHVCISDGEGKHHCECSQGYTLNADKKTCSALDRCALN 313
Score = 79.7 bits (195), Expect = 6e-15
Identities = 39/88 (44%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Query: 215 AIDYCSFGNHSCQHECVST-PGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVS 273
A D C+ G H CQH CV+ G C C EG+ L D ++C VRD C HGC+ CVS
Sbjct: 348 AQDKCALGTHGCQHICVNDRTGSHHCECYEGYTLNADKKTCSVRDKCALGSHGCQHICVS 407
Query: 274 EG-LSYRCLCPEGRQLQADGKSCNRCRE 300
+G SY C C G L D K+C+ E
Sbjct: 408 DGAASYHCDCYPGYTLNEDKKTCSATEE 435
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 212 bits (540), Expect = 6e-55
Identities = 153/503 (30%), Positives = 238/503 (47%), Gaps = 42/503 (8%)
Query: 15 QPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG 74
+P +T++Q T DLVF++D S SV F+ + F+ L+ ++G TRVG
Sbjct: 124 KPGKTEIQKCSVSAWT---DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180
Query: 75 VIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPP 134
V+QYSS ++ F L + +R+++ AI+ + TMTG AI Y + F+ + GAR
Sbjct: 181 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGAR-- 238
Query: 135 EERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVF 194
P+VA+I+TDG+ QD V A + R G+E++++G++ AD L+ +AS P HVF
Sbjct: 239 -VGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVF 297
Query: 195 LVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGG------------------ 236
V +FD I + + S++C+ G E V P
Sbjct: 298 NVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPS 357
Query: 237 ------------PRCHCREGHDLQ--PDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCL- 281
P H L P + VRDL ++ + S +
Sbjct: 358 PSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPIS 417
Query: 282 CPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGT 341
E Q C+R + D+V LVDGS S+ NF V+ F+ +V ++SP
Sbjct: 418 IMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRV 477
Query: 342 RVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA 401
++ LVQ+S TEF L ++ ++ +A+ Y T TG A+ ++ E F ++G+
Sbjct: 478 QISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGS 537
Query: 402 RPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL 461
R NVP+V ++ TDG+S D A + + + ++AVGV AV +EL IAS PAE
Sbjct: 538 RS---NVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAET 594
Query: 462 HVSYAPDFGTMTHLLENLRGSIC 484
HV DF + L SIC
Sbjct: 595 HVFTVEDFDAFQRISFELTQSIC 617
Score = 131 bits (329), Expect = 2e-30
Identities = 64/181 (35%), Positives = 112/181 (61%), Gaps = 3/181 (1%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+VLLVDGS S+ NF V+ F+++IV+ D+ P+ ++ L Q+S RTE+ L +
Sbjct: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
+ QAV + Y T+TG+AL + + +F G RPRA ++G++ TDG+SQDD
Sbjct: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA---RKIGVLITDGKSQDD 1315
Query: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 483
+ + + K+EG+ ++A+G+ A E EL+ IA++P + H DF +++ ++++L ++
Sbjct: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375
Query: 484 C 484
C
Sbjct: 1376 C 1376
Score = 110 bits (274), Expect = 4e-24
Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 356
C+ D+V L D S S+ NF V +F+ N + F ++SP G +V VQ+S V++EF
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
Query: 357 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 416
L Y A A+ + Y T TG AL + E + G R NVP+V +V T
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 2433
Query: 417 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 476
DGRSQD++ A ++ G ++ VGV EL IAS+P+E HV DF + +
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 2493
Query: 477 ENLRGSIC 484
+NL +C
Sbjct: 2494 DNLITFVC 2501
Score = 99.0 bits (245), Expect = 1e-20
Identities = 52/192 (27%), Positives = 99/192 (51%), Gaps = 4/192 (2%)
Query: 24 TGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQV 82
+G C T D+V ++D S S+ F T+R F+ ++ ++GP ++ + QYS
Sbjct: 1188 SGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDP 1247
Query: 83 QSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVA 142
++ + L A ++ + +A+ +L T+TG+A+ + F G RP R ++
Sbjct: 1248 RTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---RARKIG 1304
Query: 143 VIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLI 202
V++TDG+ QD V + + + G+E++A+G++ AD L+ +A+ P D H + V F+ +
Sbjct: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364
Query: 203 QEFGLQFQSRLC 214
LC
Sbjct: 1365 SRIVDDLTINLC 1376
Score = 92.8 bits (229), Expect = 7e-19
Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C D+VF+ D+S S+ F + +F+ + G + + P +V +QYS +V+S F
Sbjct: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L ++ + A++++ T TG A+ + + G R + VP+V V+VT
Sbjct: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 2433
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
DGR QD V + A + G ++ VGV D L +AS P + HVF+V+ F+ ++
Sbjct: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 2491
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 168 bits (426), Expect = 1e-41
Identities = 141/491 (28%), Positives = 216/491 (43%), Gaps = 55/491 (11%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
+D++F++D S SV FE + F + + GL++ P RVG Q+SS FPL +FS
Sbjct: 50 VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+++++ I+ +V T T LA++Y ++ A VP++ +IVTDG+ Q
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE--FGLQFQ 210
VA + Q + RG+ ++AVGV+ L A+AS P +HV L E + F
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224
Query: 211 SRLC--AIDYCSFGNHSCQHECVST----PGGPRCHCREGHDLQPDGRSCQ--------- 255
S +C A C H C+H + G C L C
Sbjct: 225 SAICSSATPDCRVEAHPCEHRTLEMVREFAGNAPCWRGSRRTLAVLAAHCPFYSWKRVFL 284
Query: 256 ------VRDLCNGVDHGCEFQ-------CVSEGL-SYRCLCP--EGRQLQADGKSCNRCR 299
R C G C+ Q CV EGL Y+CLCP G + K CR
Sbjct: 285 THPATCYRTTCPG---PCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCALKLSLECR 341
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
VDL+ L+D S F K FV + V + RVG+ +S + P+G
Sbjct: 342 ---VDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVG 398
Query: 360 RYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA---RPRALNVPRVGLVFT 416
Y ++ ++ + + T+TG ALR E F A RPR RV ++ T
Sbjct: 399 EYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPR-----RVVVLLT 453
Query: 417 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 476
+ S+D+++ A A+ +++ VG +AV AEL EI P HV D + + +
Sbjct: 454 ESHSEDEVAGPARHARARELLLLGVG-SEAVRAELEEITGSPK--HVMVYSDPQDLFNQI 510
Query: 477 ENLRGSICPEE 487
L+G +C +
Sbjct: 511 PELQGKLCSRQ 521
Score = 112 bits (279), Expect = 1e-24
Identities = 77/212 (36%), Positives = 109/212 (51%), Gaps = 11/212 (5%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
VD++ L+DGS SV +FE K F + D LD+SPE RVG QFSS EFPL +
Sbjct: 50 VDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFS 109
Query: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
T EVK + + + T T LAL++++ + A +VP++ ++ TDG+SQ
Sbjct: 110 TQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNA-----SVPQILIIVTDGKSQG 164
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH-LLENLRG 481
D+++ + + KE G+ ++AVGV EL +ASEP HV A T+ L L
Sbjct: 165 DVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSS 224
Query: 482 S-ICPEEGISAGTELRSPCE---CESLVEFQG 509
S IC E PCE E + EF G
Sbjct: 225 SAICSSATPDCRVEAH-PCEHRTLEMVREFAG 255
Score = 98.2 bits (243), Expect = 2e-20
Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 8/185 (4%)
Query: 289 QADGKSCNR----CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVG 344
+ GK C+R CR +DLV ++D S SV P+NF ++ FV +V+P+ T+VG
Sbjct: 512 ELQGKLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVG 571
Query: 345 LVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPR 404
LV + S+V+T F L T A + +A+ Y+ G AL H+ + + +GARP
Sbjct: 572 LVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP- 630
Query: 405 ALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIAS-EPAELHV 463
VP+ +V T GR +D +V A + + GI + VGVG + LR +A + +HV
Sbjct: 631 --GVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHV 688
Query: 464 SYAPD 468
+ D
Sbjct: 689 AAYAD 693
Score = 92.4 bits (228), Expect = 9e-19
Identities = 59/162 (36%), Positives = 80/162 (49%), Gaps = 3/162 (1%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P C T LDLVF++D+S SV P F M+ F+ V P+ T+VG++ Y SQVQ+
Sbjct: 523 PGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTA 582
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIV 145
F L R M RAI L G A+ + + +V GARP VP+ V++
Sbjct: 583 FGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARP---GVPKAVVVL 639
Query: 146 TDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASP 187
T GR + A A + R GI + VGV LR +A P
Sbjct: 640 TGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGP 681
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 149 bits (376), Expect = 6e-36
Identities = 82/187 (43%), Positives = 113/187 (60%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C+ H DLV L+D S SV ++FE V+++V +VD +V P+ TRVG+V++S R T F
Sbjct: 32 CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFE 91
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
LG +G+ EVK A + Y T TG ALR++ SFS G RPR +V ++ TD
Sbjct: 92 LGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTD 151
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
GRSQD + AA A GI ++AVGVG+A++ EL EIASEP HV + DF + +
Sbjct: 152 GRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRG 211
Query: 478 NLRGSIC 484
LR +C
Sbjct: 212 KLRRRLC 218
Score = 130 bits (327), Expect = 3e-30
Identities = 82/214 (38%), Positives = 116/214 (54%), Gaps = 6/214 (2%)
Query: 10 LLLLLQPWE----TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN 65
LL +L W Q Q G C + DLVF++D+S SV +FE +RQ++ L+
Sbjct: 12 LLWMLLLWSGGGGCQAQRAG--CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFE 69
Query: 66 VGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAF 125
VGP+ TRVGV++YS + + F L F +E+++ A R L T TG A++Y +F
Sbjct: 70 VGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSF 129
Query: 126 SVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
S G RP + +VA+++TDGR QD V + AA A GI I+AVGV A L +A
Sbjct: 130 SPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIA 189
Query: 186 SPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYC 219
S P HVF V F+ I + + + RLC C
Sbjct: 190 SEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLC 223
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 137 bits (345), Expect = 2e-32
Identities = 137/493 (27%), Positives = 217/493 (44%), Gaps = 84/493 (17%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P + D+VF+IDSS VRP F +R F+ ++R LN+GP+ RVGV+Q+S+ V
Sbjct: 1222 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1281
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L+ + + + AIR L L G+ TG A+++ F + G+R E+ VP+ V
Sbjct: 1282 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1339
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
+V G+ QD V+ A R+ GI VG + D L+ + + P VF V F +
Sbjct: 1340 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREFRELP 1397
Query: 204 EFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGV 263
+ + SFG +TP P G D P R
Sbjct: 1398 NIEERIMN--------SFG------PSAATPAPP------GVDTPPPSR----------- 1426
Query: 264 DHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELV 323
PE ++ D+V L+DGS + R +F+ V
Sbjct: 1427 -------------------PEKKK---------------ADIVFLLDGSINFRRDSFQEV 1452
Query: 324 KRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM-ERGTM 382
RFV++IVD + + +VGLVQ++S EF L + T ++ A+ V Y R
Sbjct: 1453 LRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHAN 1512
Query: 383 TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVG 442
T + L H+ + F G+R VP++ V T G+S +D + + G+ ++AVG
Sbjct: 1513 TKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVG 1571
Query: 443 VGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG----SICPEEGISAGTELR 496
V E+ +IAS A V + ++ +LE L ++CP G+ T+
Sbjct: 1572 VRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCP--GV---TDAA 1626
Query: 497 SPCECESLVEFQG 509
C + ++ F G
Sbjct: 1627 KACNLDVILGFDG 1639
Score = 95.9 bits (237), Expect = 8e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492
Query: 364 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 493 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 551
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 552 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 606
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/178 (33%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS + NF ++ F+ +++ L + + RVG+VQFS RT F L Y T
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 364 AAEVKQAVLAVEYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 421
A+V AV A+ + G + GLAL +VE+ F+ A G+R VP+V ++ + G S
Sbjct: 96 KAQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSS 153
Query: 422 DDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
D+I K+ + + +G A AEL+ IA++ + V P+F + L E L
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 209
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 414 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 531 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 587
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 588 SLVYLMDDF 596
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 820 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 878
Query: 361 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 879 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 937
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 469
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 938 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 978
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 364 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 476
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 415
Query: 477 ENLR 480
LR
Sbjct: 416 APLR 419
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 1024 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1141
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1188
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 390
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F+ID S + F + FL+ LL L +G RVGV+Q+S + +++F L +S
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 94 REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
+ + A++ L A G + GLA+ + + F+ A G+R EE VP+V V+++ G
Sbjct: 96 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSR-VEEGVPQVLVLISAGPSS 153
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D + + + + +G Q A L+ +A+ D VF V F
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF 199
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 819 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 877
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 878 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 936
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 937 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 976
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 1024 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 361 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 1141
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1179
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 627 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 685
Query: 360 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 686 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 744
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 477
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 745 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 804
Query: 478 NLRGSI 483
NL S+
Sbjct: 805 NLLKSV 810
Score = 59.7 bits (143), Expect = 7e-09
Identities = 107/468 (22%), Positives = 184/468 (39%), Gaps = 97/468 (20%)
Query: 25 GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
GP C P +L F +D+S V F MR ++ ++ L + P RV V+ Y+
Sbjct: 2186 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 2245
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
++V + R+ + I++L Q +T Q ++ A S AR +RV
Sbjct: 2246 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRV- 2296
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
+G +VA + R ASP L E V +
Sbjct: 2297 ------RNGFLMRKVAVFFSNTPTR--------------------ASPQLREAVLKLSDA 2330
Query: 200 DLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV-RD 258
+ F + + R I+ N + H V G R+ D + +C V D
Sbjct: 2331 GITPLFLTRQEDRQL-INALQINNTAVGHALVLPAG------RDLTDFLENVLTCHVCLD 2383
Query: 259 LCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQ 318
+CN +D C F S+R P R +A G + +D+ ++D +++
Sbjct: 2384 ICN-IDPSCGFG------SWR---PSFRDRRAAGSDVD------IDMAFILDSAETTTLF 2427
Query: 319 NFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSR----------VRTEFPLGRYG 362
F +K+++ +V LD+SP+ RV +VQ + V+ EF L YG
Sbjct: 2428 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2487
Query: 363 TAAEVKQAVLAVEYMERG-------TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 415
+ ++ V+++ RG G A+ + +E+ F A PR L + + L
Sbjct: 2488 SKEKL------VDFLSRGMTQLQGTRALGSAIEYTIENVFESA--PNPRDLKIVVLMLTG 2539
Query: 416 TDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAEL 461
Q ++ +AK +G +G+G+ V E+ ASEP ++
Sbjct: 2540 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDV 2587
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 631 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 688
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 689 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 747
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 748 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 784
Score = 52.8 bits (125), Expect = 8e-07
Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
+D+ F++DS+ + F+F M++++ L+R L++ P+ RV V+Q++
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471
Query: 82 -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
V+ F L + +E + + + QGT G AI+Y + F A P
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2526
Query: 136 ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
R ++ V++ G P+ ++ E V QA+ +G +G+ ++ ++ + AS P D
Sbjct: 2527 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2586
Query: 191 EHVFLVESFDLIQEFGLQFQSRL 213
LV+ + E L RL
Sbjct: 2587 VFFKLVDKSTELNEEPLMRFGRL 2609
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 137 bits (345), Expect = 2e-32
Identities = 137/493 (27%), Positives = 217/493 (44%), Gaps = 84/493 (17%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P + D+VF+IDSS VRP F +R F+ ++R LN+GP+ RVGV+Q+S+ V
Sbjct: 1428 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 1487
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L+ + + + AIR L L G+ TG A+++ F + G+R E+ VP+ V
Sbjct: 1488 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 1545
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
+V G+ QD V+ A R+ GI VG + D L+ + + P VF V F +
Sbjct: 1546 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREFRELP 1603
Query: 204 EFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGV 263
+ + SFG +TP P G D P R
Sbjct: 1604 NIEERIMN--------SFG------PSAATPAPP------GVDTPPPSR----------- 1632
Query: 264 DHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELV 323
PE ++ D+V L+DGS + R +F+ V
Sbjct: 1633 -------------------PEKKK---------------ADIVFLLDGSINFRRDSFQEV 1658
Query: 324 KRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM-ERGTM 382
RFV++IVD + + +VGLVQ++S EF L + T ++ A+ V Y R
Sbjct: 1659 LRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHAN 1718
Query: 383 TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVG 442
T + L H+ + F G+R VP++ V T G+S +D + + G+ ++AVG
Sbjct: 1719 TKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVG 1777
Query: 443 VGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG----SICPEEGISAGTELR 496
V E+ +IAS A V + ++ +LE L ++CP G+ T+
Sbjct: 1778 VRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCP--GV---TDAA 1832
Query: 497 SPCECESLVEFQG 509
C + ++ F G
Sbjct: 1833 KACNLDVILGFDG 1845
Score = 103 bits (258), Expect = 3e-22
Identities = 66/205 (32%), Positives = 109/205 (53%), Gaps = 10/205 (4%)
Query: 286 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 345
+Q QAD K+ D++ LVD S ++ ++F+LV+ F+ +V L V L
Sbjct: 26 QQQQADVKN-----GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFAL 80
Query: 346 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 405
VQF+ TEF L Y T EV + + Y+ TG L ++++ ++A G+R
Sbjct: 81 VQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSR-AG 139
Query: 406 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 465
VP+V +V TDG S+D +++ +A K + ++A+GV A E L+EIASEP +H+
Sbjct: 140 DGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFN 199
Query: 466 APDFGTMTHLLENL----RGSICPE 486
+F ++ ++ NL S+ PE
Sbjct: 200 LENFTSLHDIVGNLVSCVHSSVSPE 224
Score = 99.8 bits (247), Expect = 6e-21
Identities = 49/171 (28%), Positives = 102/171 (59%), Gaps = 1/171 (0%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F++DSS ++ F+ +R+FL +++ L VG N ++Q++ + F L +
Sbjct: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
++++ I ++ + TG ++Y M + A G+R + VP+V V++TDG +D
Sbjct: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDG-VPQVIVVLTDGHSKDG 157
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
+A +A+ ++ + ++A+GV+ AD G+L+ +AS PL+ H+F +E+F + +
Sbjct: 158 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHD 208
Score = 95.9 bits (237), Expect = 8e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
Query: 364 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 699 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 757
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 758 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 812
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/178 (33%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS + NF ++ F+ +++ L + + RVG+VQFS RT F L Y T
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
Query: 364 AAEVKQAVLAVEYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 421
A+V AV A+ + G + GLAL +VE+ F+ A G+R VP+V ++ + G S
Sbjct: 302 KAQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSS 359
Query: 422 DDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
D+I K+ + + +G A AEL+ IA++ + V P+F + L E L
Sbjct: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 415
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 620 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 676
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 677 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 736
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 737 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 793
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 794 SLVYLMDDF 802
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 1026 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 1084
Query: 361 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 1085 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 1143
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 469
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 1144 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 1184
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
Query: 364 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 563
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 476
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 621
Query: 477 ENLR 480
LR
Sbjct: 622 APLR 625
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 1230 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1347
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 1348 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1394
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 563
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 564 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F+ID S + F + FL+ LL L +G RVGV+Q+S + +++F L +S
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
Query: 94 REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
+ + A++ L A G + GLA+ + + F+ A G+R EE VP+V V+++ G
Sbjct: 302 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSR-VEEGVPQVLVLISAGPSS 359
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D + + + + +G Q A L+ +A+ D VF V F
Sbjct: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF 405
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 1025 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 1083
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 1084 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 1142
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 1143 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 1182
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 1230 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1288
Query: 361 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 1289 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 1347
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 1348 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1385
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 833 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 891
Query: 360 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 892 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 950
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 477
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 951 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 1010
Query: 478 NLRGSI 483
NL S+
Sbjct: 1011 NLLKSV 1016
Score = 59.7 bits (143), Expect = 7e-09
Identities = 107/468 (22%), Positives = 184/468 (39%), Gaps = 97/468 (20%)
Query: 25 GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
GP C P +L F +D+S V F MR ++ ++ L + P RV V+ Y+
Sbjct: 2392 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 2451
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
++V + R+ + I++L Q +T Q ++ A S AR +RV
Sbjct: 2452 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRV- 2502
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
+G +VA + R ASP L E V +
Sbjct: 2503 ------RNGFLMRKVAVFFSNTPTR--------------------ASPQLREAVLKLSDA 2536
Query: 200 DLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV-RD 258
+ F + + R I+ N + H V G R+ D + +C V D
Sbjct: 2537 GITPLFLTRQEDRQL-INALQINNTAVGHALVLPAG------RDLTDFLENVLTCHVCLD 2589
Query: 259 LCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQ 318
+CN +D C F S+R P R +A G + +D+ ++D +++
Sbjct: 2590 ICN-IDPSCGFG------SWR---PSFRDRRAAGSDVD------IDMAFILDSAETTTLF 2633
Query: 319 NFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSR----------VRTEFPLGRYG 362
F +K+++ +V LD+SP+ RV +VQ + V+ EF L YG
Sbjct: 2634 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2693
Query: 363 TAAEVKQAVLAVEYMERG-------TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 415
+ ++ V+++ RG G A+ + +E+ F A PR L + + L
Sbjct: 2694 SKEKL------VDFLSRGMTQLQGTRALGSAIEYTIENVFESA--PNPRDLKIVVLMLTG 2745
Query: 416 TDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAEL 461
Q ++ +AK +G +G+G+ V E+ ASEP ++
Sbjct: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDV 2793
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 837 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 894
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 895 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 953
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 954 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 990
Score = 52.8 bits (125), Expect = 8e-07
Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
+D+ F++DS+ + F+F M++++ L+R L++ P+ RV V+Q++
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
Query: 82 -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
V+ F L + +E + + + QGT G AI+Y + F A P
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2732
Query: 136 ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
R ++ V++ G P+ ++ E V QA+ +G +G+ ++ ++ + AS P D
Sbjct: 2733 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2792
Query: 191 EHVFLVESFDLIQEFGLQFQSRL 213
LV+ + E L RL
Sbjct: 2793 VFFKLVDKSTELNEEPLMRFGRL 2815
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 137 bits (345), Expect = 2e-32
Identities = 137/493 (27%), Positives = 217/493 (44%), Gaps = 84/493 (17%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSV 85
P + D+VF+IDSS VRP F +R F+ ++R LN+GP+ RVGV+Q+S+ V
Sbjct: 821 PAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPE 880
Query: 86 FPLRAFSRREDMERAIRDLVPLAQGT--MTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L+ + + + AIR L L G+ TG A+++ F + G+R E+ VP+ V
Sbjct: 881 FYLKTYRSQAPVLDAIRRL-RLRGGSPLNTGKALEFVARNLFVKSAGSR-IEDGVPQHLV 938
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
+V G+ QD V+ A R+ GI VG + D L+ + + P VF V F +
Sbjct: 939 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREFRELP 996
Query: 204 EFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGV 263
+ + SFG +TP P G D P R
Sbjct: 997 NIEERIMN--------SFG------PSAATPAPP------GVDTPPPSR----------- 1025
Query: 264 DHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELV 323
PE ++ D+V L+DGS + R +F+ V
Sbjct: 1026 -------------------PEKKK---------------ADIVFLLDGSINFRRDSFQEV 1051
Query: 324 KRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM-ERGTM 382
RFV++IVD + + +VGLVQ++S EF L + T ++ A+ V Y R
Sbjct: 1052 LRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHAN 1111
Query: 383 TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVG 442
T + L H+ + F G+R VP++ V T G+S +D + + G+ ++AVG
Sbjct: 1112 TKVGLEHLRVNHFVPEAGSR-LDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVG 1170
Query: 443 VGKAVEAELREIASEPA-ELHVSYAPDFGTMT-HLLENLRG----SICPEEGISAGTELR 496
V E+ +IAS A V + ++ +LE L ++CP G+ T+
Sbjct: 1171 VRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETLHDAMHETLCP--GV---TDAA 1225
Query: 497 SPCECESLVEFQG 509
C + ++ F G
Sbjct: 1226 KACNLDVILGFDG 1238
Score = 83.2 bits (204), Expect = 6e-16
Identities = 63/192 (32%), Positives = 102/192 (53%), Gaps = 11/192 (5%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 364 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 476
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 214
Query: 477 ENLRG-SICPEE 487
LR S PEE
Sbjct: 215 APLRTLSGTPEE 226
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 419 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 477
Query: 361 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 478 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 536
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 469
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 537 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 577
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 623 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 682 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 740
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 741 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 787
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 418 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 476
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 477 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 535
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 536 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 575
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 623 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 681
Query: 361 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 682 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 740
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 741 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 778
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 226 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 284
Query: 360 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 285 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 343
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 477
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 344 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 403
Query: 478 NLRGSI 483
NL S+
Sbjct: 404 NLLKSV 409
Score = 59.7 bits (143), Expect = 7e-09
Identities = 107/468 (22%), Positives = 184/468 (39%), Gaps = 97/468 (20%)
Query: 25 GP-RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG----PNATRVGVIQYS 79
GP C P +L F +D+S V F MR ++ ++ L + P RV V+ Y+
Sbjct: 1785 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDLTIAESNCPRGARVAVVTYN 1844
Query: 80 SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVP 139
++V + R+ + I++L Q +T Q ++ A S AR +RV
Sbjct: 1845 NEVTTEIRFADSKRKSVLLDKIKNL----QVALTSK--QQSLETAMSFV--ARNTFKRV- 1895
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
+G +VA + R ASP L E V +
Sbjct: 1896 ------RNGFLMRKVAVFFSNTPTR--------------------ASPQLREAVLKLSDA 1929
Query: 200 DLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQV-RD 258
+ F + + R I+ N + H V G R+ D + +C V D
Sbjct: 1930 GITPLFLTRQEDRQL-INALQINNTAVGHALVLPAG------RDLTDFLENVLTCHVCLD 1982
Query: 259 LCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQ 318
+CN +D C F S+R P R +A G + +D+ ++D +++
Sbjct: 1983 ICN-IDPSCGFG------SWR---PSFRDRRAAGSDVD------IDMAFILDSAETTTLF 2026
Query: 319 NFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSR----------VRTEFPLGRYG 362
F +K+++ +V LD+SP+ RV +VQ + V+ EF L YG
Sbjct: 2027 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2086
Query: 363 TAAEVKQAVLAVEYMERG-------TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 415
+ ++ V+++ RG G A+ + +E+ F A PR L + + L
Sbjct: 2087 SKEKL------VDFLSRGMTQLQGTRALGSAIEYTIENVFESA--PNPRDLKIVVLMLTG 2138
Query: 416 TDGRSQ-DDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAEL 461
Q ++ +AK +G +G+G+ V E+ ASEP ++
Sbjct: 2139 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDV 2186
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 230 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 287
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 288 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 346
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 347 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 383
Score = 52.8 bits (125), Expect = 8e-07
Identities = 49/203 (24%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA------TRVGVIQYSSQ----- 81
+D+ F++DS+ + F+F M++++ L+R L++ P+ RV V+Q++
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070
Query: 82 -----VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPE 135
V+ F L + +E + + + QGT G AI+Y + F A P
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESA-----PN 2125
Query: 136 ERVPRVAVIVTDGR-PQDRVAE---VAAQARARGIEIYAVGV-QRADVGSLRAMASPPLD 190
R ++ V++ G P+ ++ E V QA+ +G +G+ ++ ++ + AS P D
Sbjct: 2126 PRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPND 2185
Query: 191 EHVFLVESFDLIQEFGLQFQSRL 213
LV+ + E L RL
Sbjct: 2186 VFFKLVDKSTELNEEPLMRFGRL 2208
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 134 bits (338), Expect = 2e-31
Identities = 67/197 (34%), Positives = 118/197 (59%), Gaps = 5/197 (2%)
Query: 288 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 347
++A+G C D+VLLVDGS S+ NF V+ F+++IV+ D+ P+ ++ L Q
Sbjct: 21 IEAEGMEC--LTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78
Query: 348 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 407
+S RTE+ L + + QAV + Y T+TG+AL + + +F G RPRA
Sbjct: 79 YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRA-- 136
Query: 408 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAP 467
++G++ TDG+SQDD+ + + K+EG+ ++A+G+ A E EL+ IA++P + H
Sbjct: 137 -RKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195
Query: 468 DFGTMTHLLENLRGSIC 484
DF +++ ++++L ++C
Sbjct: 196 DFESLSRIVDDLTINLC 212
Score = 110 bits (274), Expect = 4e-24
Identities = 67/188 (35%), Positives = 97/188 (51%), Gaps = 4/188 (2%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFV-NQIVDFLDVSPEGTRVGLVQFSSRVRTEF 356
C+ D+V L D S S+ NF V +F+ N + F ++SP G +V VQ+S V++EF
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212
Query: 357 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 416
L Y A A+ + Y T TG AL + E + G R NVP+V +V T
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK---NVPKVLVVVT 1269
Query: 417 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 476
DGRSQD++ A ++ G ++ VGV EL IAS+P+E HV DF + +
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 1329
Query: 477 ENLRGSIC 484
+NL +C
Sbjct: 1330 DNLITFVC 1337
Score = 99.8 bits (247), Expect = 6e-21
Identities = 52/197 (26%), Positives = 101/197 (51%), Gaps = 4/197 (2%)
Query: 19 TQLQLTGPRCHT-GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQ 77
+ ++ G C T D+V ++D S S+ F T+R F+ ++ ++GP ++ + Q
Sbjct: 19 SSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78
Query: 78 YSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEER 137
YS ++ + L A ++ + +A+ +L T+TG+A+ + F G RP R
Sbjct: 79 YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRP---R 135
Query: 138 VPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVE 197
++ V++TDG+ QD V + + + G+E++A+G++ AD L+ +A+ P D H + V
Sbjct: 136 ARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVA 195
Query: 198 SFDLIQEFGLQFQSRLC 214
F+ + LC
Sbjct: 196 DFESLSRIVDDLTINLC 212
Score = 92.8 bits (229), Expect = 7e-19
Identities = 53/178 (29%), Positives = 91/178 (51%), Gaps = 4/178 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C D+VF+ D+S S+ F + +F+ + G + + P +V +QYS +V+S F
Sbjct: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L ++ + A++++ T TG A+ + + G R + VP+V V+VT
Sbjct: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 1269
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQE 204
DGR QD V + A + G ++ VGV D L +AS P + HVF+V+ F+ ++
Sbjct: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEK 1327
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 134 bits (336), Expect = 3e-31
Identities = 74/181 (40%), Positives = 109/181 (60%), Gaps = 3/181 (1%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V+LVDGS S+ NF LV+ F+ +V DV E TR+GL Q+S R E+ L + T
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
EV +AV + Y T+TGLAL ++ E+SF G+R V ++G++ TDG+SQDD
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILITDGKSQDD 274
Query: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 483
I + +E G+ ++A+GV A EL+EIASEP HV +F M ++E+L ++
Sbjct: 275 IIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTL 334
Query: 484 C 484
C
Sbjct: 335 C 335
Score = 118 bits (296), Expect = 1e-26
Identities = 64/189 (33%), Positives = 104/189 (55%), Gaps = 4/189 (2%)
Query: 28 CHTGPL-DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVF 86
C T + D+V ++D S S+ F F +R FL L+ +VG TR+G+ QYS + +
Sbjct: 151 CQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEW 210
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L AFS ++++ A+R+L T+TGLA+ Y +F G+R V ++ +++T
Sbjct: 211 HLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSR---TGVSKIGILIT 267
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DG+ QD + + R G+E++A+GV+ ADV L+ +AS P HV+ V FDL+
Sbjct: 268 DGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVV 327
Query: 207 LQFQSRLCA 215
LC+
Sbjct: 328 ESLTRTLCS 336
Score = 111 bits (277), Expect = 2e-24
Identities = 63/188 (33%), Positives = 102/188 (54%), Gaps = 4/188 (2%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 356
C+ DLV +VDGS S+ +NF + F+ V L+ + +GT+V +VQF+ RTEF
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085
Query: 357 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 416
L Y T + A+ + Y T TG A++++ + F+ G R +P+V +V T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRR---GIPKVIVVIT 1142
Query: 417 DGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLL 476
DGRSQDD++ + + +G ++A+GV A +EL I S+P+ HV + DF +
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202
Query: 477 ENLRGSIC 484
+ L +C
Sbjct: 1203 DELITFVC 1210
Score = 107 bits (267), Expect = 3e-23
Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 4/188 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQSVF 86
C DLVF++D S S+ F + FL + LN +G + T+V ++Q++ ++ F
Sbjct: 1026 CKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEF 1085
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
L A+ +E + AI+ + T TG AI+Y + F+ G R +P+V V++T
Sbjct: 1086 KLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTR---RGIPKVIVVIT 1142
Query: 147 DGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFG 206
DGR QD V +++ + + G I+A+GV AD L ++ S P HVF V+ FD ++
Sbjct: 1143 DGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIE 1202
Query: 207 LQFQSRLC 214
+ + +C
Sbjct: 1203 DELITFVC 1210
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 129 bits (323), Expect = 9e-30
Identities = 69/200 (34%), Positives = 119/200 (59%), Gaps = 7/200 (3%)
Query: 288 LQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQ 347
L DG+ + CR DLV ++DGS SV P+NFE+VK+++ I D+ P+ +VG+VQ
Sbjct: 21 LAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQ 80
Query: 348 FSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALN 407
+S E PLG Y + + AV ++ Y+ T TG A++ +++ F+++ +
Sbjct: 81 YSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKS------SRF 134
Query: 408 VPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVE-AELREIASEPAELHVSYA 466
+ ++ +V TDG+SQDD+ A A++ I ++A+GVG E AELR IA++P+ +V Y
Sbjct: 135 LTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYV 194
Query: 467 PDFGTMTHLLENLRGSICPE 486
D+ ++ + E ++ +C E
Sbjct: 195 EDYIAISKIREVMKQKLCEE 214
Score = 119 bits (298), Expect = 7e-27
Identities = 69/216 (31%), Positives = 114/216 (52%), Gaps = 7/216 (3%)
Query: 5 LCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
LC ++LLL + C T P DLVF++D S SV P FE ++++L+ + +
Sbjct: 8 LCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNF 67
Query: 65 NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVA 124
++GP +VGV+QYS PL ++ E + A+ ++ L T TG AIQ+A++
Sbjct: 68 DIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYL 127
Query: 125 FSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGV-QRADVGSLRA 183
F+ + + ++AV++TDG+ QD V + A AR I ++A+GV + LRA
Sbjct: 128 FAKS------SRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRA 181
Query: 184 MASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYC 219
+A+ P +VF VE + I + + +LC C
Sbjct: 182 IANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVC 217
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 118 bits (296), Expect = 1e-26
Identities = 108/458 (23%), Positives = 194/458 (42%), Gaps = 75/458 (16%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
DLVF++D S ++ FL + ++V N R+G++ YS+ +++ L++ +
Sbjct: 236 DLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ + ++ I++L + TG AI D +D
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAI-----------------------------DQMRRDG 325
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVF---LVESFDLIQEFGLQFQ 210
+E RA+G+ AV V P D+ V L + + F L Q
Sbjct: 326 FSESYGSRRAQGVPQIAVLVTHR-----------PSDDEVHDAALNLRLEDVNVFALSIQ 374
Query: 211 SRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQ 270
N++ E VS P P+ ++ + + +F
Sbjct: 375 G----------ANNTQLEEIVSYP--------------PEQTISTLKSYADLETYSTKFL 410
Query: 271 CVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQI 330
+ + + Q D C +E D+ L+DGS S++ + FE +KRF+ ++
Sbjct: 411 KKLQNEIWSQISTYAEQRNLDKTGCVDTKEA--DIHFLIDGSSSIQEKQFEQIKRFMLEV 468
Query: 331 VDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHM 390
+ + P+ RVG+VQ+S EF + Y ++++A+ ++ + GT TG AL ++
Sbjct: 469 TEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYI 528
Query: 391 VEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAE 450
++ G + R VP +V TDG S D + A R + E I ++AVG+G A + E
Sbjct: 529 LQ---IIKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIE 585
Query: 451 LREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEG 488
L+EIA + E VS+ +F + + + IC E+G
Sbjct: 586 LQEIAGK--EERVSFGQNFDALKSIKNEVVREICAEKG 621
Score = 103 bits (257), Expect = 4e-22
Identities = 58/190 (30%), Positives = 103/190 (54%), Gaps = 5/190 (2%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
T D+ F+ID S S++ +FE +++F++ + ++GP+ RVGV+QYS + F +
Sbjct: 438 TKEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYIT 497
Query: 90 AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
+S D+ +AI ++ L GT TG A+ Y + + + G + +VP +++TDG
Sbjct: 498 DYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQI---IKNGMKDRMSKVPCYLIVLTDGM 554
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
DRV E A + RA I ++AVG+ A+ L+ +A +E V ++FD ++ +
Sbjct: 555 STDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAGK--EERVSFGQNFDALKSIKNEV 612
Query: 210 QSRLCAIDYC 219
+CA C
Sbjct: 613 VREICAEKGC 622
Score = 93.6 bits (231), Expect = 4e-19
Identities = 51/160 (31%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C + D++ LVD S S+ +NF +K F+ ++ + + + T++G+VQFS + + EF
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L RY T E+ A+ + + GT+TG AL + V F+ ++GAR L + ++ TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKAL-NFVGQYFTHSKGAR---LGAKKFLILITD 737
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASE 457
G +QDD+ A + + + +++VGV A ++L EI+ +
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD 777
Score = 92.4 bits (228), Expect = 9e-19
Identities = 55/192 (28%), Positives = 105/192 (54%), Gaps = 6/192 (3%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C D++F++DSS S+ F M+ F+ LL + +G + T++GV+Q+S + + F
Sbjct: 622 CEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEFQ 681
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L + ++++ AI + + +GT+TG A+ + + F+ ++GAR + + +++TD
Sbjct: 682 LNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VGQYFTHSKGARLGAK---KFLILITD 737
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
G QD V + A R + + I++VGV A+ L ++ VF VE+FD ++
Sbjct: 738 GVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGD--SSLVFHVENFDHLKALER 795
Query: 208 QFQSRLCAIDYC 219
+ R+CA+ C
Sbjct: 796 KLIFRVCALHDC 807
Score = 80.1 bits (196), Expect = 5e-15
Identities = 53/184 (28%), Positives = 97/184 (52%), Gaps = 6/184 (3%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LD+VFV+D S S++ + M + L++ +VG + + G ++YS Q +F L +S
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG--RP 150
R + +R T T A+++A N F+ G+R ++ V ++ +++TDG
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKHA-NALFTEEHGSR-IKQNVKQMLIVITDGESHD 930
Query: 151 QDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ 210
D++ + A + R +GI I+AVGV +A+ L MA + V++FD +++ Q
Sbjct: 931 HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988
Query: 211 SRLC 214
R+C
Sbjct: 989 ERMC 992
Score = 76.3 bits (186), Expect = 7e-14
Identities = 60/246 (24%), Positives = 112/246 (45%), Gaps = 16/246 (6%)
Query: 302 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 361
+ D+V LVD S + P++F VK F+N++++ L + RV L Q+S +EF L +
Sbjct: 28 YADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQYSDEFHSEFHLSTF 87
Query: 362 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420
G + + +++ G AL+ FS R R P + +V S
Sbjct: 88 KGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRK-QFPPILVVLASAES 146
Query: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGT----MTHLL 476
+D++ + +++G+ + +VGV KA E L+ +A+ ++ D T MT ++
Sbjct: 147 EDEVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNLRTIRDLSTFSQNMTQII 206
Query: 477 ENLRGSICPEEGISAGTELRSPCECES--------LVEFQGRTLGALESLTLNLAQLTAR 528
+++ + E + A ++ P C+ LV+ T G L L L +T+
Sbjct: 207 KDV--TKYKEGAVDADMQVHFPISCQKDSLADLVFLVDESLGTGGNLRHLQTFLENITSS 264
Query: 529 LEDLEN 534
++ EN
Sbjct: 265 MDVKEN 270
Score = 75.9 bits (185), Expect = 9e-14
Identities = 54/183 (29%), Positives = 91/183 (49%), Gaps = 10/183 (5%)
Query: 9 VLLLLLQPWETQL--QLTGPRCHTGPL--DLVFVIDSSRSVRPFEFETMRQFLMGLLRGL 64
+++ +L W L Q GP GP+ D+VF++DSS + P F ++ F+ ++ L
Sbjct: 5 LIIFVLIIWTETLADQSPGP----GPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSL 60
Query: 65 NVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTM-TGLAIQYAMNV 123
+ N RV + QYS + S F L F R M ++ G++ G A+Q A
Sbjct: 61 PIEANKYRVALAQYSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRT 120
Query: 124 AFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRA 183
FS R ++ P + V++ +D V E + + G++I +VGVQ+A +L+A
Sbjct: 121 YFSAPINGR-DRKQFPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKA 179
Query: 184 MAS 186
MA+
Sbjct: 180 MAT 182
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/189 (27%), Positives = 89/189 (47%), Gaps = 6/189 (3%)
Query: 299 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPL 358
++ DLV LVD S N ++ F+ I +DV R+GL+ +S+ +T L
Sbjct: 231 KDSLADLVFLVDESLGTGG-NLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFL 289
Query: 359 GRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
T +E +Q + + + TG A+ M FSE+ G+R RA VP++ ++ T
Sbjct: 290 KSSTTQSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSR-RAQGVPQIAVLVTHR 348
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTM----TH 474
S D++ A + E + ++A+ + A +L EI S P E +S + + T
Sbjct: 349 PSDDEVHDAALNLRLEDVNVFALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTK 408
Query: 475 LLENLRGSI 483
L+ L+ I
Sbjct: 409 FLKKLQNEI 417
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/186 (25%), Positives = 90/186 (48%), Gaps = 6/186 (3%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
+D+V ++D S S++ Q + + +V DV + + G +++S + F L Y
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+ + + + T T AL+H F+E G+R + NV ++ +V TDG S D
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKH-ANALFTEEHGSRIKQ-NVKQMLIVITDGESHD 930
Query: 423 --DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480
++ A + +GI ++AVGVGKA + EL +A + + Y +F + + ++
Sbjct: 931 HDQLNDTALELRNKGITIFAVGVGKANQKELEGMAGN--KNNTIYVDNFDKLKDVFTLVQ 988
Query: 481 GSICPE 486
+C E
Sbjct: 989 ERMCTE 994
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/176 (23%), Positives = 78/176 (44%), Gaps = 4/176 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
CH D++F+ D S V +F TM FL L+ ++ ++G+ Q+ S QS+
Sbjct: 999 CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIE 1058
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L+ + + I+++ A++ N+ F++ G R VP+ V++T
Sbjct: 1059 LKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNM-FNLHAGGR-RNAGVPQTLVVITS 1116
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
G P+ VA+ + GI + +G+ DV + E + + FD ++
Sbjct: 1117 GDPRYDVADAVKTLKDLGICVLVLGI--GDVYKEHLLPITGNSEKIITFQDFDKLK 1170
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/183 (24%), Positives = 84/183 (45%), Gaps = 24/183 (13%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD------VSPEGTRVGLVQFS---- 349
+ ++D+V L+D S+++ F+ VK V+ ++D + +S G R+ L+ +S
Sbjct: 1959 DSYMDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWES 2018
Query: 350 -----SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMT-GLALRHMVEHSFSEAQGARP 403
V+TEF Y +K + G T G AL E+ F E R
Sbjct: 2019 SRRKMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRK 2078
Query: 404 RALNVPRVGLVFTDGRS---QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAE 460
+V V + G + ++ + + A RAK +G V++ + +G + ++ E+AS P +
Sbjct: 2079 H-----KVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLD 2133
Query: 461 LHV 463
H+
Sbjct: 2134 QHL 2136
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C D++ L DGS V +F + F++ ++D D+ + ++G+ QF S ++
Sbjct: 999 CHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDIQSQRMKIGMAQFGSNYQSIIE 1058
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L T + K + V AL+ V + F+ G R R VP+ +V T
Sbjct: 1059 LKNSLTKTQWKTQIQNVSKSGGFPRIDFALK-KVSNMFNLHAGGR-RNAGVPQTLVVITS 1116
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAEL 461
G + D++ K+ GI + +G+G + L I ++
Sbjct: 1117 GDPRYDVADAVKTLKDLGICVLVLGIGDVYKEHLLPITGNSEKI 1160
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/182 (23%), Positives = 82/182 (45%), Gaps = 18/182 (9%)
Query: 299 REGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRVGLVQFS--- 349
+E ++D+ L+D S+ V F+ VK F+ ++D+ ++P G RV ++ +S
Sbjct: 2286 QEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPG 2345
Query: 350 -------SRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 402
V EF L Y + ++K + + + G AL+ +++ F R
Sbjct: 2346 YMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLR 2405
Query: 403 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVG-KAVEAELREIASEPAEL 461
+ + + T+ +D + + RAK +G ++ G K + EL E+AS P +
Sbjct: 2406 KNKV-IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHNDKELEELASHPLDH 2464
Query: 462 HV 463
H+
Sbjct: 2465 HL 2466
Score = 47.0 bits (110), Expect = 4e-05
Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 28/183 (15%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN------ATRVGVIQYS------- 79
+D+ F+ID+S+ V EF+ ++ F+ +L ++ P RV V+ YS
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349
Query: 80 ---SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEE 136
V F L ++ M+ ++D L G A+Q+ ++ F P
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVF-----VGTPNL 2404
Query: 137 RVPRVAVIVTDGR----PQDRVAEVAAQARARG--IEIYAVGVQRADVGSLRAMASPPLD 190
R +V +++ G +D + V+ +A+ +G I +++ G + D L +AS PLD
Sbjct: 2405 RKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPKHND-KELEELASHPLD 2463
Query: 191 EHV 193
H+
Sbjct: 2464 HHL 2466
Score = 44.7 bits (104), Expect = 2e-04
Identities = 39/180 (21%), Positives = 79/180 (43%), Gaps = 24/180 (13%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN------VGPNATRVGVIQYS------- 79
+D+VF+ID+SR++ EF+ ++ + ++ N + + R+ ++ YS
Sbjct: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRR 2021
Query: 80 --SQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMT-GLAIQYAMNVAFSVAEGARPPEE 136
V++ F + + M+ I+ G T G A+ + F P
Sbjct: 2022 KMGTVKTEFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLF-----PETPYL 2076
Query: 137 RVPRVAVIVTDGRPQDR---VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHV 193
R +V +V+ G +R V +A +A+ +G I+ + + + +AS PLD+H+
Sbjct: 2077 RKHKVIFVVSAGENYERKEFVKMMALRAKCQGYVIFVISLGSTRKDDMEELASYPLDQHL 2136
Score = 39.3 bits (90), Expect = 0.009
Identities = 31/139 (22%), Positives = 59/139 (42%), Gaps = 10/139 (7%)
Query: 297 RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVS----PEGTRVGLVQFSSRV 352
+C +LV +D S V ++F + + IV+ L++ P G RV +V ++S
Sbjct: 1751 KCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGT 1810
Query: 353 RTEFPLGRYGTAAEVKQAVLAVEYME--RGTMTGLALRHMVEHSFSEAQGARPRALNVPR 410
Y ++ Q + ++Y + G A+R + + F NV R
Sbjct: 1811 SYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYA----GANVRR 1866
Query: 411 VGLVFTDGRSQDDISVWAA 429
V + F++G++ S+ A
Sbjct: 1867 VAVFFSNGQTASRSSIITA 1885
Score = 38.9 bits (89), Expect = 0.012
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 12/149 (8%)
Query: 27 RCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPN----ATRVGVIQYSSQV 82
+C P +LVF +D+S V F R + ++ LN+ N RV ++ Y+S
Sbjct: 1751 KCPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGT 1810
Query: 83 QSVFPLRAFSRREDMERAIRDL--VPLAQGTMTGLAIQY-AMNVAFSVAEGARPPEERVP 139
+ ++R++ + + + + + G A+++ NV GA V
Sbjct: 1811 SYLIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAGA-----NVR 1865
Query: 140 RVAVIVTDGRPQDRVAEVAAQARARGIEI 168
RVAV ++G+ R + + A ++I
Sbjct: 1866 RVAVFFSNGQTASRSSIITATMEFSALDI 1894
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 118 bits (295), Expect = 2e-26
Identities = 76/223 (34%), Positives = 117/223 (52%), Gaps = 5/223 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS S+ +F+ VK F+ ++ ++ P+ +VGL Q+S +TE+ L T
Sbjct: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
+V AV + Y T TGLAL H++ + A G RP A +V ++ TDG+SQDD
Sbjct: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEA---AKVVILVTDGKSQDD 295
Query: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 483
+ A K+ G+ ++AVGV A EAELR +AS P ++ V DF + L L I
Sbjct: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355
Query: 484 CPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLT 526
C + + G+ + P +L T L +T + +L+
Sbjct: 356 C--QRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLS 396
Score = 107 bits (268), Expect = 2e-23
Identities = 59/168 (35%), Positives = 91/168 (54%), Gaps = 3/168 (1%)
Query: 32 PLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAF 91
P D+VF++D S S+ F+ ++ FL ++ +GP+ +VG+ QYS Q+ + L +
Sbjct: 177 PADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSL 236
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S +E + A+R L T TGLA+ + + A G RP +V ++VTDG+ Q
Sbjct: 237 STKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP---EAAKVVILVTDGKSQ 293
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V A + G+ ++AVGV+ AD LR +ASPP D V V F
Sbjct: 294 DDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDF 341
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 110 bits (276), Expect = 2e-24
Identities = 61/201 (30%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
Query: 286 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 345
R D +C++ D+ ++DGS SV NF V +FV + ++S TR+G
Sbjct: 492 RVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGA 551
Query: 346 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 405
VQ++ R EF +Y + ++ A+ V Y GT TG A+ +E F +++
Sbjct: 552 VQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP----- 606
Query: 406 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 465
N ++ ++ TDGRS DD+ + A A +G++ YA+GV A + EL IA+ PA H +
Sbjct: 607 -NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFF 665
Query: 466 APDFGTMTHLLENLRGSICPE 486
+F + + + +IC E
Sbjct: 666 VDEFDNLHQYVPRIIQNICTE 686
Score = 94.7 bits (234), Expect = 2e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ FVID S SV F T+ QF+ L + + TR+G +QY+ + + F +S
Sbjct: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ D+ AI+ + + GT TG AI +A+ F ++ P +R ++ +++TDGR D
Sbjct: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSK----PNKR--KLMILITDGRSYDD 623
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
V A A +G+ YA+GV A L +A+ P +H F V+ FD + ++ + +
Sbjct: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
Query: 214 C 214
C
Sbjct: 684 C 684
Score = 79.7 bits (195), Expect = 6e-15
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 6/167 (3%)
Query: 21 LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
+ L P C +DL F+ID S S+ F +Q L + + L++GP +GV+QY
Sbjct: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354
Query: 81 QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
+ F L+ + D++ AI + + G AI + FS A G R P
Sbjct: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411
Query: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASP 187
V V++ DG P D+V E + AR GI I+ + ++ A + + P
Sbjct: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEP 458
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
+DL L+DGS S+ + F + K+ + + LD+ P G +G+VQ+ T F L +
Sbjct: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
Query: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+ ++K A+ + + G A+ + ++ FS+A G R A P V +V DG D
Sbjct: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGA---PNVVVVMVDGWPTD 423
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
+ + A+E GI ++ + + A E E ++ EP
Sbjct: 424 KVEEASRLARESGINIFFITIEGAAENE-KQYVVEP 458
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 109 bits (273), Expect = 6e-24
Identities = 62/180 (34%), Positives = 99/180 (55%), Gaps = 6/180 (3%)
Query: 24 TGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQ 83
T C D++F++DSS S+ P F M+ F+ L+ +GP+ ++GV+Q+S +
Sbjct: 612 TEEACKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINK 671
Query: 84 SVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
F L F + D+ AI + + Q T+TG A+ + FS +GARP + + +
Sbjct: 672 EEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSFVSQY-FSPTKGARP---NIRKFLI 727
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQ 203
++TDG QD V E A R G+ IY+VGV ++V L ++ P E VF VE+FD++Q
Sbjct: 728 LITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMVFYVENFDILQ 785
Score = 107 bits (266), Expect = 4e-23
Identities = 60/187 (32%), Positives = 106/187 (56%), Gaps = 6/187 (3%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C+E D++ LVD S S+ P+NF +K F+ +V + P+ ++G+VQFS + EF
Sbjct: 616 CKEMKADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQ 675
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
L R+ + +++ A+ + ++ + T+TG AL V FS +GARP N+ + ++ TD
Sbjct: 676 LNRFMSQSDISNAIDQMAHIGQTTLTGSAL-SFVSQYFSPTKGARP---NIRKFLILITD 731
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 477
G +QD + A ++EG+++Y+VGV + +L EI+ P V Y +F + + +
Sbjct: 732 GEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPE--MVFYVENFDILQRIED 789
Query: 478 NLRGSIC 484
+L IC
Sbjct: 790 DLVFGIC 796
Score = 101 bits (251), Expect = 2e-21
Identities = 59/157 (37%), Positives = 87/157 (55%), Gaps = 2/157 (1%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 357
C VDLV L+DGS S++P +F+ +K F+ +V DVS R+G QFS EFP
Sbjct: 994 CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053
Query: 358 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 417
LG + E+ + ++ + T G ALR VEH F G+R P+V LV TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALRE-VEHYFRPDMGSRINT-GTPQVLLVLTD 1111
Query: 418 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREI 454
G+SQD+++ A + GI +Y+VG+G + +L +I
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQLIQI 1148
Score = 97.8 bits (242), Expect = 2e-20
Identities = 63/185 (34%), Positives = 99/185 (53%), Gaps = 7/185 (3%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+ LL+DGS S + +F +K F++++V +++P RVG VQ++ EF + +Y
Sbjct: 436 DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGA-RPRALNVPRVGLVFTDGRSQD 422
++ +A+ + M T TG AL + S Q A + R VP +V T+G S+D
Sbjct: 496 KQDLGKAIENIRQMGGNTNTGAAL----NFTLSLLQKAKKQRGNKVPCHLVVLTNGMSKD 551
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGS 482
I A R +EE I +YA+G+ +A + +LREIA E E V Y DF + + +
Sbjct: 552 SILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQVVQE 609
Query: 483 ICPEE 487
IC EE
Sbjct: 610 ICTEE 614
Score = 94.7 bits (234), Expect = 2e-19
Identities = 50/190 (26%), Positives = 99/190 (52%), Gaps = 5/190 (2%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
T D+ +ID S S + +F M+ FL ++ N+ P+ RVG +QY+ F +
Sbjct: 432 TEEADIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEIN 491
Query: 90 AFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
+S ++D+ +AI ++ + T TG A+ + +++ + + + +VP V++T+G
Sbjct: 492 KYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSL---LQKAKKQRGNKVPCHLVVLTNGM 548
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQF 209
+D + E A + R I +YA+G++ A+ LR +A ++ V+ V FD +++ Q
Sbjct: 549 SKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAGE--EKRVYYVHDFDALKDIRNQV 606
Query: 210 QSRLCAIDYC 219
+C + C
Sbjct: 607 VQEICTEEAC 616
Score = 91.7 bits (226), Expect = 2e-18
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 4/187 (2%)
Query: 28 CHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFP 87
C +DLVF++D S S++P +F+ M++FL +++ +V N R+G Q+S FP
Sbjct: 994 CEIDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFP 1053
Query: 88 LRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTD 147
L F +++ I ++ + T G A++ + F G+R P+V +++TD
Sbjct: 1054 LGTFIGEKEISFQIENIKQIFGNTHIGAALREVEHY-FRPDMGSR-INTGTPQVLLVLTD 1111
Query: 148 GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGL 207
G+ QD VA+ A R RGI+IY+VG+ DV + + E V +FD +++
Sbjct: 1112 GQSQDEVAQAAEALRHRGIDIYSVGI--GDVDDQQLIQITGTAEKKLTVHNFDELKKVNK 1169
Query: 208 QFQSRLC 214
+ +C
Sbjct: 1170 RIVRNIC 1176
Score = 82.8 bits (203), Expect = 7e-16
Identities = 54/169 (31%), Positives = 95/169 (56%), Gaps = 6/169 (3%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LD+VFVIDSS S+ E+ M+ F++GL++ +VG N R G ++Y+ + +F L F
Sbjct: 808 LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFG 867
Query: 93 RREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ- 151
+ ++ +++ + T T A+ ++ ++ F+ A G+R + VP+V +++TDG
Sbjct: 868 TKLEVISVLQNDQAMGGSTYTAEALGFSDHM-FTEARGSR-LNKGVPQVLIVITDGESHD 925
Query: 152 -DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D++ A R +GI + AVG+ A+ L AMA + F VE+F
Sbjct: 926 ADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGS--SDKYFFVETF 972
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/202 (29%), Positives = 102/202 (50%), Gaps = 7/202 (3%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V L+D S + +NF+ +K F+ + V LD+ RVGLV +S+ + L
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
+EV Q + + TG A++ + + FS G+R + VP++ ++ T S+D+
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDN 347
Query: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMT----HLLENL 479
++ A + EG+ ++ +G+ A + +L +IAS PAE +VS F + L+ L
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTFADLAAHNQTFLKKL 407
Query: 480 RGSICPEEGI-SAGTE-LRSPC 499
R I + S TE L+S C
Sbjct: 408 RNQITHTVSVFSERTETLKSGC 429
Score = 82.0 bits (201), Expect = 1e-15
Identities = 47/166 (28%), Positives = 89/166 (53%), Gaps = 1/166 (0%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S + F+ ++ FL + L++ N RVG++ YS++ + + L
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+ ++ + I++L P TG AI+ FS G+R + VP++AV+VT +D
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSR-KNQGVPQIAVLVTHRDSEDN 347
Query: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
V + A R G+ I+ +G++ A L +AS P +++V +++F
Sbjct: 348 VTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHPAEQYVSKLKTF 393
Score = 73.6 bits (179), Expect = 4e-13
Identities = 46/154 (29%), Positives = 79/154 (51%), Gaps = 2/154 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++DSS + F ++ F+ ++ L + + RV + QYS ++ S F L F
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 94 REDMERAIRDLVPLAQGTM-TGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
R M +R G++ G A+Q A FS R +++ P + V++ +D
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGR-DKKQFPPILVVLASSESED 145
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMAS 186
V E + R G++I +VGVQ+A +L+AMA+
Sbjct: 146 NVEEASKALRKDGVKIISVGVQKASEENLKAMAT 179
Score = 72.4 bits (176), Expect = 1e-12
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 6/184 (3%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
+D+V ++D S S+ + ++K F+ +V DV R G ++++ F L +G
Sbjct: 808 LDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFG 867
Query: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
T EV + + M T T AL +H F+EA+G+R VP+V +V TDG S D
Sbjct: 868 TKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEARGSRLNK-GVPQVLIVITDGESHD 925
Query: 423 --DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR 480
++ A +++GI++ AVG+ A EL +A + + FG + + ++
Sbjct: 926 ADKLNATAKALRDKGILVLAVGIDGANPVELLAMAGSSDKYF--FVETFGGLKGIFSDVT 983
Query: 481 GSIC 484
S+C
Sbjct: 984 ASVC 987
Score = 65.9 bits (159), Expect = 9e-11
Identities = 43/183 (23%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Query: 302 HVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRY 361
+ D+V LVD S + ++F VK F+ +++ L + + RV L Q+S ++ +EF L +
Sbjct: 25 YADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTF 84
Query: 362 -GTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS 420
G + + ++ G AL+ FS R + P + +V S
Sbjct: 85 KGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKK-QFPPILVVLASSES 143
Query: 421 QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG----TMTHLL 476
+D++ + +++G+ + +VGV KA E L+ +A+ ++ D MTH++
Sbjct: 144 EDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTVRDLSMFSQNMTHII 203
Query: 477 ENL 479
+++
Sbjct: 204 KDV 206
Score = 49.7 bits (117), Expect = 7e-06
Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 12/164 (7%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVG----VIQYSSQ 81
P C P +LVF +D SR V EFE M++ + L+R + V N+ VG ++ Y+S
Sbjct: 1749 PECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYNSH 1808
Query: 82 VQSVFPLRAFSRREDMERAIRDLVPLAQGTMT---GLAIQYAMNVAFSVAEGARPPEERV 138
+ + ++ + R I + +P + + + G A+++ F P
Sbjct: 1809 ARHLVRFSDAYKKSQLLREI-ETIPYERSSASREIGRAMRFISRNVFK----RTLPGAHT 1863
Query: 139 PRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLR 182
++A + G+ D + A +EI V + ++V S+R
Sbjct: 1864 RKIATFFSSGQSADAHSITTAAMEFGALEIIPVVITFSNVPSVR 1907
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 31/196 (15%)
Query: 294 SCNRCR----EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPE------GTRV 343
SC++ R + ++D L+D S+++ FE ++ F+ ++D +++PE G RV
Sbjct: 1951 SCDQARPPPVQSYMDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRV 2010
Query: 344 GLVQFS----------SRVRTEFPLGRYGTAAEVKQAV-LAVEYMERGTMTGLALRHMVE 392
L+ + S VR EF L Y + +K+ V +V+ + G AL+ ++
Sbjct: 2011 ALLSHAPPDFLPNTQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLD 2070
Query: 393 HSFSEAQGARPRALNVPRVGLVFTDGRSQ----DDISVWAARAKEEGIVMYAVGVGKA-V 447
+ F R +V V + G + + + + RAK +G ++ +G
Sbjct: 2071 NVFLSTPNLRRN-----KVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWD 2125
Query: 448 EAELREIASEPAELHV 463
+ EL ++AS P + H+
Sbjct: 2126 DKELEDLASHPLDHHL 2141
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/183 (23%), Positives = 80/183 (43%), Gaps = 27/183 (14%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGP------NATRVGVIQYS------- 79
+D F++D+SR++ EFE +R FL LL + P RV ++ ++
Sbjct: 1964 MDAAFLLDASRNMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPN 2023
Query: 80 ---SQVQSVFPLRAFSRREDMERAIRDLVPLAQG-TMTGLAIQYAMNVAFSVAEGARPPE 135
S V++ F L + + M+R + + V G G A+Q+ ++ F P
Sbjct: 2024 TQKSPVRAEFNLTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVF-----LSTPN 2078
Query: 136 ERVPRVAVIVTDGRPQDRVAEV----AAQARARGIEIYAVGVQRA-DVGSLRAMASPPLD 190
R +V +++ G E+ + +A+ +G ++ + D L +AS PLD
Sbjct: 2079 LRRNKVIFVISAGETSHLDGEILKKESLRAKCQGYALFVFSLGPIWDDKELEDLASHPLD 2138
Query: 191 EHV 193
H+
Sbjct: 2139 HHL 2141
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 108 bits (269), Expect = 2e-23
Identities = 70/208 (33%), Positives = 105/208 (50%), Gaps = 8/208 (3%)
Query: 283 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD--VSPEG 340
P R + +C R D+V L+DGS S+ NF V+ F+ +V S +G
Sbjct: 19 PRVRAQHRERVTCTRLYAA--DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQG 76
Query: 341 TRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQG 400
R VQ+S RTEF L G+ +V +A+ + Y T TG A+ H+ +H F Q
Sbjct: 77 VRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLP-QL 135
Query: 401 ARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAE 460
ARP VP+V ++ TDG+SQD + A R K +G+ ++AVG+ A EL+ +AS+P
Sbjct: 136 ARP---GVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTS 192
Query: 461 LHVSYAPDFGTMTHLLENLRGSICPEEG 488
+ DF + LL + +C G
Sbjct: 193 DFFFFVNDFSILRTLLPLVSRRVCTTAG 220
Score = 98.2 bits (243), Expect = 2e-20
Identities = 60/183 (32%), Positives = 98/183 (53%), Gaps = 6/183 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA--TRVGVIQYSSQVQSVFPLRAF 91
D+VF++D S S+ F +R FL GL+ + +A R +QYS ++ F L A
Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
D+ RAIR+L T TG AI + + F + + ARP VP+V +++TDG+ Q
Sbjct: 98 GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVF-LPQLARPG---VPKVCILITDGKSQ 153
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQS 211
D V A + + +G++++AVG++ AD L+ +AS P + F V F +++
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSR 213
Query: 212 RLC 214
R+C
Sbjct: 214 RVC 216
Score = 52.8 bits (125), Expect = 8e-07
Identities = 46/167 (27%), Positives = 79/167 (47%), Gaps = 6/167 (3%)
Query: 26 PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLN-VGPNATRVGVIQYSSQVQS 84
P C G D+VF+ +++ E R+ L L+ L +GP A +VG++ YS +
Sbjct: 1046 PVCPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSP 1104
Query: 85 VFPLRAFSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
+FPL + + IRD+ + G G A+ A + +A A + VP V V
Sbjct: 1105 LFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHR--YMLAPDAPGRRQHVPGVMV 1162
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
++ D + + +A+A G+ + +G+ AD LR +A P +D
Sbjct: 1163 LLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA-PGMD 1208
Score = 48.9 bits (115), Expect = 1e-05
Identities = 46/190 (24%), Positives = 83/190 (43%), Gaps = 6/190 (3%)
Query: 298 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF 356
C G D+V L ++ E +R + ++V L + P+ +VGL+ +S R F
Sbjct: 1048 CPRGLADVVFLPHATQD-NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLF 1106
Query: 357 PLGRYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVF 415
PL + Q + + YM+ G G A+ + H + A A R +VP V ++
Sbjct: 1107 PLNGSHDLGIILQRIRDMPYMDPSGNNLGTAV--VTAHRYMLAPDAPGRRQHVPGVMVLL 1164
Query: 416 TDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFG-TMTH 474
D + DI A+ G+ + +G+ A +LR +A + +A D G ++
Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224
Query: 475 LLENLRGSIC 484
+ L ++C
Sbjct: 1225 AVSGLATALC 1234
>gi|205277471 cochlin precursor [Homo sapiens]
Length = 550
Score = 103 bits (256), Expect = 5e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 295 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 354
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
Query: 355 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 414
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
Query: 415 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 474
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
Query: 475 LLENLRGSIC 484
++ ++ IC
Sbjct: 533 IVSDVIRGIC 542
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 283 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 342
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
Query: 343 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 402
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
Query: 403 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 451
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
Query: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
Query: 193 VFLVESF 199
F F
Sbjct: 521 AFFTREF 527
Score = 66.2 bits (160), Expect = 7e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
Query: 154 VAEVAAQARARGIEIYAVGVQR 175
+ E AR G+ ++ V V +
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK 303
>gi|4758022 cochlin precursor [Homo sapiens]
Length = 550
Score = 103 bits (256), Expect = 5e-22
Identities = 60/190 (31%), Positives = 98/190 (51%), Gaps = 5/190 (2%)
Query: 295 CNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT 354
C++ V++ L+DGS SV NF L+ FV+ I ++S G ++ VQF+ RT
Sbjct: 358 CSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRT 417
Query: 355 EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLV 414
EF Y T V + + YM GT TG A+ V + F + + + V +
Sbjct: 418 EFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLV-----I 472
Query: 415 FTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTH 474
TDG+S DD+ AA A + GI +++VGV A +L+++AS+P E H + +F +
Sbjct: 473 VTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEP 532
Query: 475 LLENLRGSIC 484
++ ++ IC
Sbjct: 533 IVSDVIRGIC 542
Score = 89.4 bits (220), Expect = 8e-18
Identities = 54/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 283 PEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTR 342
P G++L+ + ++ D+ L+DGS ++ + F L K FV ++ L + EG
Sbjct: 144 PTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPH 203
Query: 343 VGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGAR 402
VGLVQ S + EF L + +A +V A+ V + + TG AL+H + F+ G R
Sbjct: 204 VGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR 263
Query: 403 PRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAEL 451
+P+V +VF DG DDI A+E G+ ++ V V K + EL
Sbjct: 264 K---GIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEEL 309
Score = 81.6 bits (200), Expect = 2e-15
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 5/187 (2%)
Query: 13 LLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATR 72
L+Q T Q+ + +++ F+ID S SV F M +F+ + + + +
Sbjct: 346 LVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAK 405
Query: 73 VGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGAR 132
+ +Q++ ++ F +S +E++ IR++ ++ GT TG AI + + F
Sbjct: 406 IAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIR--- 462
Query: 133 PPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEH 192
E VIVTDG+ D V AA A GI I++VGV A + L+ MAS P + H
Sbjct: 463 --ESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESH 520
Query: 193 VFLVESF 199
F F
Sbjct: 521 AFFTREF 527
Score = 66.2 bits (160), Expect = 7e-11
Identities = 39/142 (27%), Positives = 71/142 (50%), Gaps = 3/142 (2%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+ F+ID S ++ F + F+ + L +G VG++Q S + F L+ F+
Sbjct: 165 DIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTS 224
Query: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
+D+ AI+++ + TG A+++ F+V G R + +P+V V+ DG P D
Sbjct: 225 AKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVR---KGIPKVVVVFIDGWPSDD 281
Query: 154 VAEVAAQARARGIEIYAVGVQR 175
+ E AR G+ ++ V V +
Sbjct: 282 IEEAGIVAREFGVNVFIVSVAK 303
>gi|40068485 von Willebrand factor A domain containing 1 isoform 1
[Homo sapiens]
Length = 445
Score = 102 bits (255), Expect = 7e-22
Identities = 67/180 (37%), Positives = 92/180 (51%), Gaps = 4/180 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
DL+ L+D S SV F V+ FV Q+V L + R LV SR TEFP G++ +
Sbjct: 34 DLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYTEFPFGQHSS 93
Query: 364 AAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDD 423
+ AV A T TGLAL + E F+EA GARP VP+V + TDG S D
Sbjct: 94 GEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVWVTDGGSSDP 150
Query: 424 ISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSI 483
+ K+ G+ ++ V G+ EL AS PAE H+ + D + +++ LRGSI
Sbjct: 151 VGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFV-DVDDLHIIVQELRGSI 209
Score = 95.5 bits (236), Expect = 1e-19
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (1%)
Query: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
GP DL+F++DSS SV +EF +R+F+ L+ L +G A R ++ S+ +
Sbjct: 25 GPPASAPRGDLMFLLDSSASVSHYEFSRVREFVGQLVAPLPLGTGALRASLVHVGSRPYT 84
Query: 85 VFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVI 144
FP S E + A+R T TGLA+ YA F+ A GARP VP+V V
Sbjct: 85 EFPFGQHSSGEAAQDAVRASAQRMGDTHTGLALVYAKEQLFAEASGARP---GVPKVLVW 141
Query: 145 VTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL 201
VTDG D V + + G+ ++ V R + L A AS P ++H+ V+ DL
Sbjct: 142 VTDGGSSDPVGPPMQELKDLGVTVFIVSTGRGNFLELSAAASAPAEKHLHFVDVDDL 198
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 99.0 bits (245), Expect = 1e-20
Identities = 63/197 (31%), Positives = 109/197 (55%), Gaps = 20/197 (10%)
Query: 19 TQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQY 78
T++ GP+C PL+LVFVIDSS SV P F+ ++ F+ + + + R+G+I Y
Sbjct: 783 TEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINY 842
Query: 79 SSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERV 138
S +V+ V L+ FS ++D + A+ ++ L +GT T A+Q A + E ARP V
Sbjct: 843 SHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQ----AANDMFEDARP---GV 895
Query: 139 PRVAVIVTDG----RPQDRVAEVAAQARARGIEIYAVGVQRADVGS-------LRAMASP 187
+VA+++TDG R ++++ EV A +EI+ +GV + + + + +A+
Sbjct: 896 KKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATD 955
Query: 188 PLDEHVFLVESFDLIQE 204
P EHV+ + F +Q+
Sbjct: 956 P--EHVYQFDDFFTLQD 970
Score = 79.7 bits (195), Expect = 6e-15
Identities = 57/202 (28%), Positives = 102/202 (50%), Gaps = 21/202 (10%)
Query: 297 RCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEF 356
+C+E ++LV ++D S+SV P+NF+++K FV + D + + R+G++ +S +V
Sbjct: 791 KCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGIINYSHKVEKVA 850
Query: 357 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 416
L ++ + + K AV ++Y+ GT T AL + + + ARP V +V LV T
Sbjct: 851 NLKQFSSKDDFKLAVDNMQYLGEGTYTATAL----QAANDMFEDARP---GVKKVALVIT 903
Query: 417 DG----RSQDDISVWAARAKEEGIVMYAVGVGK-------AVEAELREIASEPAELHVSY 465
DG R ++ ++ A + + ++ +GV K E+ IA++P HV
Sbjct: 904 DGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPE--HVYQ 961
Query: 466 APDFGTMTHLL-ENLRGSICPE 486
DF T+ L + L IC +
Sbjct: 962 FDDFFTLQDTLKQKLFQKICED 983
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/222 (21%), Positives = 92/222 (41%), Gaps = 18/222 (8%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGL---LRGLNVGPNA---TRVGVIQYSSQVQSVF 86
+D+VF++DSS S + F+ + F+ L + L G + ++ +Q+SS VQ
Sbjct: 47 IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106
Query: 87 PLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVT 146
P ++ + ++ ++ + + QGT + AI A + R + +V +++T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLL------KREGRKDGVKVVLLMT 160
Query: 147 DGRPQDR---VAEVAAQARARGIEIYAVGVQR-ADVGSLRAMASPPLDEHVFLVESFDLI 202
DG + V ++ AR GI + + + LR ++ E L+ L+
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLV 220
Query: 203 QEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREG 244
+ +Q + + C C+ PG P H G
Sbjct: 221 DK--IQDRLDILFEKKCERKICECEKGDPGDPGPPGTHGNPG 260
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/165 (24%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEG------TRVGLVQFSSRVRTEF 356
+D+V +VD S+S + F+ K FV+ + D + G ++ +QFSS V+ +
Sbjct: 47 IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDP 106
Query: 357 PLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFT 416
P + KQ V ++ + +GT + A+ + + +G + +V L+ T
Sbjct: 107 PFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATR--LLKREGRKDGV----KVVLLMT 160
Query: 417 DG---RSQDDISVWAARAKEEGIVMYAVGVGKAV-EAELREIASE 457
DG D+ + A+ GI + + V EA+LR I+ +
Sbjct: 161 DGIDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGD 205
>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
sapiens]
Length = 1036
Score = 95.9 bits (237), Expect = 8e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 232 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 291
Query: 364 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 292 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 350
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 351 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 405
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 213 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 269
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 270 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 329
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 330 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 386
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 387 SLVYLMDDF 395
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 619 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 677
Query: 361 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 678 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 736
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 469
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 737 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 777
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 364 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 476
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 214
Query: 477 ENLR 480
LR
Sbjct: 215 APLR 218
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 823 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 940
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 941 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 987
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 38 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 97
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 98 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 156
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 157 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 618 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 676
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 677 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 735
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 736 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 775
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 823 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 881
Query: 361 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 882 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 940
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 941 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 978
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 426 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 484
Query: 360 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 485 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 543
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 477
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 544 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 603
Query: 478 NLRGSI 483
NL S+
Sbjct: 604 NLLKSV 609
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 430 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 487
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 488 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 546
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 547 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 583
>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
sapiens]
Length = 1237
Score = 95.9 bits (237), Expect = 8e-20
Identities = 62/177 (35%), Positives = 100/177 (56%), Gaps = 4/177 (2%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS +V NF V+ FV +V+ LD+ + RVGLVQFS TEF L Y T
Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 492
Query: 364 AAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
+++ + ++ G TG AL ++ + F+EA G+R R +VP++ L+ T G+S+D
Sbjct: 493 KSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIRE-HVPQLLLLLTAGQSED 551
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
A GI+ + VG +A +AEL +IA P+ +++ DF ++ L + L
Sbjct: 552 SYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSSLPALPQQL 606
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/178 (33%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D++ L+DGS + NF ++ F+ +++ L + + RVG+VQFS RT F L Y T
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 364 AAEVKQAVLAVEYMERGTMT--GLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQ 421
A+V AV A+ + G + GLAL +VE+ F+ A G+R VP+V ++ + G S
Sbjct: 96 KAQVLGAVKALGF-AGGELANIGLALDFVVENHFTRAGGSRVEE-GVPQVLVLISAGPSS 153
Query: 422 DDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENL 479
D+I K+ + + +G A AEL+ IA++ + V P+F + L E L
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKL 209
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 8/189 (4%)
Query: 13 LLQPWETQLQLTG-PRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNAT 71
LL P T L+G P H+ D++F++D S +V F +R F+M L+ L++G +
Sbjct: 414 LLAPLRT---LSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNI 470
Query: 72 RVGVIQYSSQVQSVFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEG 130
RVG++Q+S + F L + + D+ +R L + G TG A+ Y F+ A G
Sbjct: 471 RVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGG 530
Query: 131 ARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLD 190
+R E VP++ +++T G+ +D + A GI + VG +A+ L +A P
Sbjct: 531 SR-IREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNP-- 587
Query: 191 EHVFLVESF 199
V+L++ F
Sbjct: 588 SLVYLMDDF 596
Score = 83.2 bits (204), Expect = 6e-16
Identities = 59/170 (34%), Positives = 87/170 (51%), Gaps = 12/170 (7%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+ VR F L+K FV ++V+ LDV + RV +VQ+S R R EF L
Sbjct: 820 GEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNS 878
Query: 361 YGTAAEVKQAVLAVEYMERGT-MTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
Y +V AV + + T TG AL ++ + + G+R VP++ +V T R
Sbjct: 879 YMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITE-GVPQLLIVLTADR 937
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDF 469
S DD+ + K G V +G+G A E++ I S+ PDF
Sbjct: 938 SGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTI---------SFIPDF 978
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query: 304 DLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGT 363
D+V LVDGS ++ NF ++ F+ +++ L++ + +V + Q++ VR EF + T
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 364 AAEVKQAVLAVEYMERGTM-TGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
EV AV ++ ++ + TG AL + + F+ + G R A +P++ ++ T G+S D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASE------PAELHVSYAPDFGTMTHLL 476
+IS A K I+ +A+G A +AEL EIA + PAE AP G + LL
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRA--APLQGMLPGLL 415
Query: 477 ENLR 480
LR
Sbjct: 416 APLR 419
Score = 76.3 bits (186), Expect = 7e-14
Identities = 55/170 (32%), Positives = 93/170 (54%), Gaps = 6/170 (3%)
Query: 31 GPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRA 90
G D+VF+ID S+S P EF+ +R + L+ L+VG + TRV VIQ+S + F L A
Sbjct: 1024 GKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 91 FSRREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGR 149
S +++++ A++ L P + G A++Y F G+R EE VP+ V+++ G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSR-IEEGVPQFLVLISSGK 1141
Query: 150 PQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D V + A + + G+ + + + AD L ++ P E+VF V +F
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTF 1188
Score = 74.7 bits (182), Expect = 2e-13
Identities = 41/153 (26%), Positives = 80/153 (52%), Gaps = 2/153 (1%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D+VF++D S ++ F +R F+ +++ L +G + +V V QY+ V+ F
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 298
Query: 94 REDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQD 152
+ ++ A+R + PL TG A+ + N F+ + G R E +P++ V++T G+ D
Sbjct: 299 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYR-AAEGIPKLLVLITGGKSLD 357
Query: 153 RVAEVAAQARARGIEIYAVGVQRADVGSLRAMA 185
+++ A + + I +A+G + AD L +A
Sbjct: 358 EISQPAQELKRSSIMAFAIGNKGADQAELEEIA 390
Score = 74.3 bits (181), Expect = 3e-13
Identities = 50/168 (29%), Positives = 86/168 (51%), Gaps = 6/168 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
D++F+ID S + F + FL+ LL L +G RVGV+Q+S + +++F L +S
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 94 REDMERAIRDLVPLAQGTMT--GLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
+ + A++ L A G + GLA+ + + F+ A G+R EE VP+V V+++ G
Sbjct: 96 KAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSR-VEEGVPQVLVLISAGPSS 153
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESF 199
D + + + + +G Q A L+ +A+ D VF V F
Sbjct: 154 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEF 199
Score = 73.9 bits (180), Expect = 3e-13
Identities = 44/160 (27%), Positives = 85/160 (53%), Gaps = 3/160 (1%)
Query: 30 TGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLR 89
+G D+VF++D S VR F +++F+ ++ L+VG + RV V+QYS + + F L
Sbjct: 819 SGEKDVVFLLDGSEGVRS-GFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLN 877
Query: 90 AFSRREDMERAIRDLVPLAQGT-MTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDG 148
++ ++D+ A+R L L T TG A+++ + + G+R E VP++ +++T
Sbjct: 878 SYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSR-ITEGVPQLLIVLTAD 936
Query: 149 RPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
R D V + + G +G+ AD+ ++ ++ P
Sbjct: 937 RSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 976
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Query: 301 GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR 360
G D+V L+DGS+S P+ F+ V+ + ++VD+LDV + TRV ++QFS + EF L
Sbjct: 1024 GKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKVEFLLNA 1082
Query: 361 YGTAAEVKQAVLAVEYM-ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ + EV+ AV + R G AL ++ + F G+R VP+ ++ + G+
Sbjct: 1083 HSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE-GVPQFLVLISSGK 1141
Query: 420 SQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
S D++ A K+ G+ + + A + EL +I+ P
Sbjct: 1142 SDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP 1179
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 4/186 (2%)
Query: 300 EGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLG 359
E D++ L DGS ++ Q F +V+ F+ +I+D L+V PEGTR+ + Q+S V+ E
Sbjct: 627 ESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFD 685
Query: 360 RYGTAAEVKQAVLAVEYME-RGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDG 418
+ + E+ V ++ + G AL + + F ++ G+R V + ++ G
Sbjct: 686 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIED-GVLQFLVLLVAG 744
Query: 419 RSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPA-ELHVSYAPDFGTMTHLLE 477
RS D + A+ K+ G+V + A AEL +I PA L P G + +
Sbjct: 745 RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIV 804
Query: 478 NLRGSI 483
NL S+
Sbjct: 805 NLLKSV 810
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/157 (28%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Query: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS--QVQSVFPLRAF 91
D++F+ D S ++ +F +R FL ++ LNV P TR+ V QYS +V+S F
Sbjct: 631 DILFLFDGSANLVG-QFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ- 688
Query: 92 SRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
S+ E + R + + G A+ YA F + G+R E+ V + V++ GR
Sbjct: 689 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR-IEDGVLQFLVLLVAGRSS 747
Query: 152 DRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPP 188
DRV A+ + G+ + + AD L + P
Sbjct: 748 DRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSP 784
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 94.4 bits (233), Expect = 2e-19
Identities = 101/440 (22%), Positives = 180/440 (40%), Gaps = 90/440 (20%)
Query: 25 GPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQS 84
GP+ ++ LD+ FV++ S + +F ++F+ +++ ++VG ++ V V+QYS V
Sbjct: 1489 GPKRNSMVLDVAFVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTV 1548
Query: 85 VFPLRAFSRREDMERAIRDL-VPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAV 143
+P + D+ + +R++ T TGLA++Y + +F V++G R E+ P +
Sbjct: 1549 EYPFSEAQSKGDILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDR---EQAPNLVY 1605
Query: 144 IVTDGRPQDRVAEVAAQARARGIEIYAVGV-QRADVGSLRAMASPPLDEHVFLVESFDLI 202
+VT D + + I++ +GV A+V L + P L++ F+ +
Sbjct: 1606 MVTGNPASDEIKRLPGD-----IQVVPIGVGPNANVQELERIGWP---NAPILIQDFETL 1657
Query: 203 QEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNG 262
RE DL V C
Sbjct: 1658 P--------------------------------------REAPDL--------VLQRC-- 1669
Query: 263 VDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFEL 322
C EGL L P C++ +D++LL+DGS S F+
Sbjct: 1670 --------CSGEGLQIPTLSP--------APDCSQ----PLDVILLLDGSSSFPASYFDE 1709
Query: 323 VKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER--- 379
+K F + ++ P T+V ++Q+ S + P + E + V+ M+R
Sbjct: 1710 MKSFAKAFISKANIGPRLTQVSVLQYGSITTIDVP---WNVVPEKAHLLSLVDVMQREGG 1766
Query: 380 GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY 439
+ G AL V + SE GARP A V ++ TD S D + A A+ + ++
Sbjct: 1767 PSQIGDALGFAVRYLTSEMHGARPGASKA--VVILVTD-VSVDSVDAAADAARSNRVTVF 1823
Query: 440 AVGVGKAVEAELREIASEPA 459
+G+G +A I + PA
Sbjct: 1824 PIGIGDRYDAAQLRILAGPA 1843
Score = 81.6 bits (200), Expect = 2e-15
Identities = 104/473 (21%), Positives = 186/473 (39%), Gaps = 71/473 (15%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LDLVF++D S + EFE ++ F++ ++ L + RV V++Y + L+
Sbjct: 1276 LDLVFLLDGSSRLSEAEFEVLKAFVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRK 1335
Query: 93 RREDMERAIRDLVPLA--QGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRP 150
R ++ R I V A Q T ++Y + FS + RP R+ + + + +
Sbjct: 1336 RPSELRR-IASQVKYAGSQVASTSEVLKYTLFQIFSKID--RPEASRITLLLMASQEPQR 1392
Query: 151 QDR-VAEVAAQARARGIEIYAVGV-QRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ 208
R + + + + VG+ A++ +R + + F++ S D +++ +
Sbjct: 1393 MSRNFVRYVQGLKKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVLSSVDELEQQRDE 1452
Query: 209 FQSRLCAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCE 268
S LC + P P L PD V GV
Sbjct: 1453 IVSYLCDL----------------APEAP------PPTLPPDMAQVTVGPGLLGVS---- 1486
Query: 269 FQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVN 328
L P+ + D + +++GS + +F K F+
Sbjct: 1487 -----------TLGPKRNSMVLD-------------VAFVLEGSDKIGEADFNRSKEFME 1522
Query: 329 QIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM-ERGTMTGLAL 387
+++ +DV + V ++Q+S V E+P + ++ Q V + Y T TGLAL
Sbjct: 1523 EVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGDILQRVREIRYQGGNRTNTGLAL 1582
Query: 388 RHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVG-KA 446
R++ +HSF +QG R +A P + + T + D+I + I + +GVG A
Sbjct: 1583 RYLSDHSFLVSQGDREQA---PNLVYMVTGNPASDEI-----KRLPGDIQVVPIGVGPNA 1634
Query: 447 VEAELREIASEPAELHVSYAPDFGTMTHLLENL-RGSICPEEGISAGTELRSP 498
EL I A + + DF T+ +L C EG+ T +P
Sbjct: 1635 NVQELERIGWPNAPILIQ---DFETLPREAPDLVLQRCCSGEGLQIPTLSPAP 1684
Score = 72.8 bits (177), Expect = 8e-13
Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 45/313 (14%)
Query: 7 WPVLLLLLQPWETQLQ----LTGPRCHTG----------------PLDLVFVIDSSRSVR 46
WP +L+Q +ET + L RC +G PLD++ ++D S S
Sbjct: 1644 WPNAPILIQDFETLPREAPDLVLQRCCSGEGLQIPTLSPAPDCSQPLDVILLLDGSSSFP 1703
Query: 47 PFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVP 106
F+ M+ F + N+GP T+V V+QY S P + + + +
Sbjct: 1704 ASYFDEMKSFAKAFISKANIGPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVMQR 1763
Query: 107 LAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGI 166
+ G A+ +A+ S GARP + V ++VTD D V A AR+ +
Sbjct: 1764 EGGPSQIGDALGFAVRYLTSEMHGARPGASKA--VVILVTD-VSVDSVDAAADAARSNRV 1820
Query: 167 EIYAVGV-QRADVGSLRAMASPPLDEHVF---LVESFDLIQEFGLQFQSRLCA--IDYC- 219
++ +G+ R D LR +A P D +V +E + G F +LC+ + C
Sbjct: 1821 TVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTMVTLGNSFLHKLCSGFVRICM 1880
Query: 220 -SFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQC------- 271
GN + + P +CH QPDG++ N D G C
Sbjct: 1881 DEDGNEKRPGDVWTLP--DQCHT---VTCQPDGQTLLKSHRVN-CDRGLRPSCPNSQSPV 1934
Query: 272 -VSEGLSYRCLCP 283
V E R CP
Sbjct: 1935 KVEETCGCRWTCP 1947
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 88.2 bits (217), Expect = 2e-17
Identities = 69/239 (28%), Positives = 112/239 (46%), Gaps = 18/239 (7%)
Query: 294 SCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVR 353
S C D+V L+DGS S+ +NF + FV ++ T+ L+QFS++ +
Sbjct: 141 SRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVIS--QFQRPSTQFSLMQFSNKFQ 198
Query: 354 TEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGL 413
T F + ++ + +V ++ T T A++++V F + GAR A ++ +
Sbjct: 199 THFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDA---AKILI 255
Query: 414 VFTDGRSQDDISVW---AARAKEEGIVMYAVGVGKAVE-----AELREIASEPAELHVSY 465
V TDG+ + D + A GI+ YA+GVG A + EL +IAS+P++ H+
Sbjct: 256 VITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFK 315
Query: 466 APDFGTMTHLLENLRGSICPEEGI----SAGTELRSPCECESLV-EFQGRTLGALESLT 519
DF + + L+ I EG S+ EL E S V G LGA+ S T
Sbjct: 316 VEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGPVLGAVGSFT 374
Score = 80.1 bits (196), Expect = 5e-15
Identities = 69/246 (28%), Positives = 111/246 (45%), Gaps = 23/246 (9%)
Query: 10 LLLLLQPWET--QLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVG 67
L LL P + +L ++ C D+VF+ID S S+ F TM F+ ++
Sbjct: 125 LCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ-- 182
Query: 68 PNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSV 127
+T+ ++Q+S++ Q+ F F R + + + L T T AIQ ++ F
Sbjct: 183 RPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHA 242
Query: 128 AEGARPPEERVPRVAVIVTDGRPQDR---VAEVAAQARARGIEIYAVGV-----QRADVG 179
+ GAR ++ +++TDG+ + +V A A GI YA+GV R
Sbjct: 243 SYGAR---RDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSWK 299
Query: 180 SLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAID------YCSFGNHSCQH--ECV 231
L +AS P EH+F VE FD +++ Q + ++ AI+ SF Q V
Sbjct: 300 ELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFSAV 359
Query: 232 STPGGP 237
TP GP
Sbjct: 360 FTPDGP 365
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 84.7 bits (208), Expect = 2e-16
Identities = 60/193 (31%), Positives = 105/193 (54%), Gaps = 24/193 (12%)
Query: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
+D+V+++DGS S+ P ++ V F+N +++ +D+ P+ T+VG+VQ+ V EF L +Y
Sbjct: 171 LDIVIVLDGSNSIYP--WDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYS 228
Query: 363 TAAEVKQAVLAVEYMERG---TMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGR 419
+ EV V A + ++RG TMT L + + +F+EA+GAR V +V ++ TDG
Sbjct: 229 STEEV--LVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGAR---RGVKKVMVIVTDGE 283
Query: 420 SQDD--ISVWAARAKEEGIVMYAVGV-----------GKAVEAELREIASEPAELHVSYA 466
S D+ + ++E I +++ + K VE E++ IASEP E H
Sbjct: 284 SHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVE-EIKSIASEPTEKHFFNV 342
Query: 467 PDFGTMTHLLENL 479
D + +++ L
Sbjct: 343 SDELALVTIVKTL 355
Score = 82.0 bits (201), Expect = 1e-15
Identities = 58/177 (32%), Positives = 90/177 (50%), Gaps = 18/177 (10%)
Query: 33 LDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFS 92
LD+V V+D S S+ P++ T FL LL +++GP T+VG++QY V F L +S
Sbjct: 171 LDIVIVLDGSNSIYPWDSVTA--FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYS 228
Query: 93 RREDMERAIRDLVPL-AQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQ 151
E++ A + +V + TMT L I A AF+ A GAR V +V VIVTDG
Sbjct: 229 STEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGAR---RGVKKVMVIVTDGESH 285
Query: 152 D--RVAEVAAQARARGIEIYAVGV----------QRADVGSLRAMASPPLDEHVFLV 196
D R+ +V I+ +++ + V ++++AS P ++H F V
Sbjct: 286 DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNV 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,107,078
Number of Sequences: 37866
Number of extensions: 900448
Number of successful extensions: 3717
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 2146
Number of HSP's gapped (non-prelim): 1085
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.