Search of human proteins with 61966777

Search of human proteins with 61966777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s...   859   0.0  
gi|197116396 hypothetical protein LOC284677 [Homo sapiens]            191   1e-48
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...   141   1e-33
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]       103   2e-22
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     89   7e-18
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom...    87   2e-17
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom...    87   2e-17
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s...    75   1e-13
gi|148664205 endothelial cell adhesion molecule [Homo sapiens]         73   5e-13
gi|8393638 F11 receptor precursor [Homo sapiens]                       71   2e-12
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s...    69   1e-11
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]    59   1e-08
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]    59   1e-08
gi|66346706 neuronal growth regulator 1 [Homo sapiens]                 53   4e-07
gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]           49   1e-05
gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens]           49   1e-05
gi|221316762 neurotrimin isoform 4 [Homo sapiens]                      48   2e-05
gi|221316757 neurotrimin isoform 3 [Homo sapiens]                      48   2e-05
gi|115298665 neurotrimin isoform 2 [Homo sapiens]                      48   2e-05
gi|7705413 neurotrimin isoform 1 [Homo sapiens]                        48   2e-05
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       46   7e-05
gi|19743806 roundabout 1 isoform b [Homo sapiens]                      45   9e-05
gi|4506569 roundabout 1 isoform a [Homo sapiens]                       45   9e-05
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...    45   2e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         44   2e-04
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         44   2e-04
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    44   2e-04
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    44   2e-04
gi|59939900 opioid binding protein/cell adhesion molecule-like i...    42   8e-04
gi|4505505 opioid binding protein/cell adhesion molecule-like is...    42   8e-04

>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
           sapiens]
          Length = 414

 Score =  859 bits (2220), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MRVGGAFHLLLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDI 60
           MRVGGAFHLLLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDI
Sbjct: 1   MRVGGAFHLLLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDI 60

Query: 61  EWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSD 120
           EWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSD
Sbjct: 61  EWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSD 120

Query: 121 TATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKW 180
           TATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKW
Sbjct: 121 TATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKW 180

Query: 181 AKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCT 240
           AKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCT
Sbjct: 181 AKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCT 240

Query: 241 VANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGAR 300
           VANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGAR
Sbjct: 241 VANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGAR 300

Query: 301 GAFGYGNGGGVGGGACGDLASEIREDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKY 360
           GAFGYGNGGGVGGGACGDLASEIREDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKY
Sbjct: 301 GAFGYGNGGGVGGGACGDLASEIREDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKY 360

Query: 361 APPPCGGPEDVALAPCTAAAACEAGPSPVYVKVKSAEPADCAEGPVQCKNGLLV 414
           APPPCGGPEDVALAPCTAAAACEAGPSPVYVKVKSAEPADCAEGPVQCKNGLLV
Sbjct: 361 APPPCGGPEDVALAPCTAAAACEAGPSPVYVKVKSAEPADCAEGPVQCKNGLLV 414


>gi|197116396 hypothetical protein LOC284677 [Homo sapiens]
          Length = 235

 Score =  191 bits (485), Expect = 1e-48
 Identities = 90/91 (98%), Positives = 91/91 (100%)

Query: 324 REDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALAPCTAAAACE 383
           +EDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALAPCTAAAACE
Sbjct: 21  QEDAVAPGCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPPCGGPEDVALAPCTAAAACE 80

Query: 384 AGPSPVYVKVKSAEPADCAEGPVQCKNGLLV 414
           AGPSPVYVKVKSAEPADCAEGPVQCKNGLLV
Sbjct: 81  AGPSPVYVKVKSAEPADCAEGPVQCKNGLLV 111


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score =  141 bits (355), Expect = 1e-33
 Identities = 90/267 (33%), Positives = 136/267 (50%), Gaps = 36/267 (13%)

Query: 29  QEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHHR--ENVFLSYQDKRIN 86
           +E++  A+G+   L C + L PED GP  LDIEW+     PA ++  + V + Y   +I 
Sbjct: 26  EEMIEKAKGETAYLPCKFTLSPEDQGP--LDIEWL---ISPADNQKVDQVIILYSGDKIY 80

Query: 87  HGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT-MATRKVIVTVQAR 145
               P L+ RV F ++D    DASIN+ NLQ+SD  TY+C+VKK   +A +K+ + V  +
Sbjct: 81  DDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVK 140

Query: 146 PAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSEL 205
           P+   C+ +G    G+D  +KC    GS PL Y+W K+S               S     
Sbjct: 141 PSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLS--------------DSQKMPT 186

Query: 206 SYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVK-VSDSRRIGV 264
           S+     SS+        + +K+ S    G Y CTV N VG   C++ +  V  S + G+
Sbjct: 187 SWLAEMTSSV--------ISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGL 238

Query: 265 IIGIVLGSLLALGCLAVGIWGLVCCCC 291
           I G ++G+LLAL  +     GL+  CC
Sbjct: 239 IAGAIIGTLLALALI-----GLIIFCC 260


>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
          Length = 373

 Score =  103 bits (258), Expect = 2e-22
 Identities = 94/353 (26%), Positives = 153/353 (43%), Gaps = 58/353 (16%)

Query: 26  GDGQEVLYLAEGDNVRLGCPYVLD-PEDYGPNGLDIEWMQVNSDPAHHRENVFLSYQDKR 84
           G   E+  +AE + V L C + L  PE    + LDIEW+  +++     + V ++Y  + 
Sbjct: 18  GTHTEIKRVAE-EKVTLPCHHQLGLPEK---DTLDIEWLLTDNEG---NQKVVITYSSRH 70

Query: 85  INHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKT-TMATRKVIVTVQ 143
           + +      + RV FA++  +  DAS+ +  L+ SD   Y C+VK +       VI+ V 
Sbjct: 71  VYNNLTEEQKGRVAFASNFLAG-DASLQIEPLKPSDEGRYTCKVKNSGRYVWSHVILKVL 129

Query: 144 ARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHS 203
            RP+ P C  EG +T G+D+ L+C +S G++P+ Y W +I             S+  Y+ 
Sbjct: 130 VRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYN- 188

Query: 204 ELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIG 263
                           + G ++L++++ +  GLYQCT  N  G   CVV V V   + IG
Sbjct: 189 ----------------HPGRVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQYVQSIG 232

Query: 264 VIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNGGGVGGGACGDLASEI 323
           ++ G V G +     + + +W L+            +    Y            +  +EI
Sbjct: 233 MVAGAVTGIVAGALLIFLLVWLLI----------RRKDKERYEE---------EERPNEI 273

Query: 324 REDAVAP------------GCKASGRGSRVTHLLGYPTQNVSRSLRRKYAPPP 364
           REDA AP            G ++S  GS  T           R+L    AP P
Sbjct: 274 REDAEAPKARLVKPSSSSSGSRSSRSGSSSTRSTANSASRSQRTLSTDAAPQP 326


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 81/286 (28%), Positives = 122/286 (42%), Gaps = 45/286 (15%)

Query: 19  LSAVRINGDG------QEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHH 72
           L AVR+  D       Q+VL  ++G +V L C Y          GL I+W ++     H 
Sbjct: 12  LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSR--EGL-IQWDKLLL--THT 66

Query: 73  RENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT 132
              V   + +K   HG L   + RV  + ++  Q DASI +  L ++D  TYEC V   +
Sbjct: 67  ERVVIWPFSNKNYIHGEL--YKNRVSIS-NNAEQSDASITIDQLTMADNGTYECSVSLMS 123

Query: 133 ----MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHY 188
                   +V + V   P+ P C  EG    GN++ L C +  GS    Y W + +    
Sbjct: 124 DLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYN---- 179

Query: 189 PYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYS 248
                           +  QE     + Q  +   + LK+IS    G Y CT +N  G  
Sbjct: 180 ----------------ILNQE---QPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220

Query: 249 VCVVEVKV-SDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGG 293
            C + V V S S  + + +GI +G + AL  + + I+   CCCC G
Sbjct: 221 FCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIY---CCCCRG 263


>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
           sapiens]
          Length = 431

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 75/285 (26%), Positives = 123/285 (43%), Gaps = 50/285 (17%)

Query: 58  LDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQ 117
           L++ WM      A+  E V L YQ  ++  G+ P    RV F  + P+  + SI + N Q
Sbjct: 55  LNVIWMVTPLSNANQPEQVIL-YQGGQMFDGA-PRFHGRVGFTGTMPAT-NVSIFINNTQ 111

Query: 118 VSDTATYECRVKKTTMATRKVI----VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGS 173
           +SDT TY+C V        + I    +TV   P+ P C  +G    G+DV+L C +  G 
Sbjct: 112 LSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGI 171

Query: 174 QPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRAD 233
              +Y W K+                              +  Q    G + +++IS   
Sbjct: 172 PRPTYLWEKLDN----------------------TLKLPPTATQDQVQGTVTIRNISALS 209

Query: 234 DGLYQCTVANNVGYSVCVVEVKV--SDSRRIGVIIGIV-LGSLLALGCLAVGIWGLVCCC 290
            GLYQC  +N +G S C+++++V     R IG+I G +  G+++ + C+A+ +       
Sbjct: 210 SGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALIL------- 262

Query: 291 CGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDAVAPGCKAS 335
                     GAF Y            ++ +EIRED + P C ++
Sbjct: 263 ----------GAFFYWRSKNKEEEE-EEIPNEIREDDLPPKCSSA 296


>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
           sapiens]
          Length = 430

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 75/285 (26%), Positives = 123/285 (43%), Gaps = 50/285 (17%)

Query: 58  LDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQ 117
           L++ WM      A+  E V L YQ  ++  G+ P    RV F  + P+  + SI + N Q
Sbjct: 54  LNVIWMVTPLSNANQPEQVIL-YQGGQMFDGA-PRFHGRVGFTGTMPAT-NVSIFINNTQ 110

Query: 118 VSDTATYECRVKKTTMATRKVI----VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGS 173
           +SDT TY+C V        + I    +TV   P+ P C  +G    G+DV+L C +  G 
Sbjct: 111 LSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGI 170

Query: 174 QPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRAD 233
              +Y W K+                              +  Q    G + +++IS   
Sbjct: 171 PRPTYLWEKLDN----------------------TLKLPPTATQDQVQGTVTIRNISALS 208

Query: 234 DGLYQCTVANNVGYSVCVVEVKV--SDSRRIGVIIGIV-LGSLLALGCLAVGIWGLVCCC 290
            GLYQC  +N +G S C+++++V     R IG+I G +  G+++ + C+A+ +       
Sbjct: 209 SGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALIL------- 261

Query: 291 CGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDAVAPGCKAS 335
                     GAF Y            ++ +EIRED + P C ++
Sbjct: 262 ----------GAFFYWRSKNKEEEE-EEIPNEIREDDLPPKCSSA 295


>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
           sapiens]
          Length = 327

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 62/244 (25%), Positives = 101/244 (41%), Gaps = 49/244 (20%)

Query: 95  QRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKT----TMATRKVIVTVQARPAVPM 150
           +RV    + P+   A++ L ++  SDT TY C+V       T     + +TV   P+ P+
Sbjct: 90  KRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTVLVPPSNPL 149

Query: 151 CWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQES 210
           C   G  + G    L+C +S G+    Y W ++                      ++   
Sbjct: 150 CSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLG---------------------TFPTP 188

Query: 211 FHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV---SDSRRIGVIIG 267
              S+ Q   +G L+L ++S    G Y+C   N +G + C + + V   S  R  G +IG
Sbjct: 189 SPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGALIG 248

Query: 268 IVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDA 327
           ++LG LL    L+V  +    C        G +    YG              S++REDA
Sbjct: 249 VLLGVLL----LSVAAF----CLVRFQKERGKKPKETYG-------------GSDLREDA 287

Query: 328 VAPG 331
           +APG
Sbjct: 288 IAPG 291


>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
          Length = 390

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 85/310 (27%), Positives = 126/310 (40%), Gaps = 60/310 (19%)

Query: 97  VRFAASDPSQYDASINLMNLQVSDTATYECRV-------KKTTMATRKVIVTVQARPAVP 149
           V    S PS+ + S+ L  LQ  D+  Y C V       K    + + + + V   PA P
Sbjct: 98  VSLVYSMPSR-NLSLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPP 156

Query: 150 MCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQE 209
            C  +G    G +V L C +      + Y+W +      P                S+Q 
Sbjct: 157 SCRLQGVPHVGANVTLSCQSPRSKPAVQYQWDR----QLP----------------SFQT 196

Query: 210 SFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIV 269
            F  +++  +  G L L ++S +  G+Y C   N VG + C V ++VS      V+ G V
Sbjct: 197 FFAPALD--VIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEVSTGPGAAVVAGAV 254

Query: 270 LGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDAVA 329
           +G+L+ LG LA    GLV                 Y       G A  + A++I+EDA+A
Sbjct: 255 VGTLVGLGLLA----GLVLL---------------YHR----RGKALEEPANDIKEDAIA 291

Query: 330 PGCKASGRGSRVTHLLGYPTQNVS-RSLRRKYAPPPCGGPEDVALAPCTAAAACEAGPSP 388
           P      + S      G  +   S R+LR     PP G P   AL P T + + +A PSP
Sbjct: 292 PRTLPWPKSSDTISKNGTLSSVTSARALR-----PPHGPPRPGALTP-TPSLSSQALPSP 345

Query: 389 VYVKVKSAEP 398
                  A P
Sbjct: 346 RLPTTDGAHP 355


>gi|8393638 F11 receptor precursor [Homo sapiens]
          Length = 299

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 74/283 (26%), Positives = 108/283 (38%), Gaps = 47/283 (16%)

Query: 9   LLLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSD 68
           +L + L    L +V ++    EV  + E + V+L C Y       G +   +EW     D
Sbjct: 16  ILAILLCSLALGSVTVHSSEPEVR-IPENNPVKLSCAYS------GFSSPRVEWKFDQGD 68

Query: 69  PAH---HRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYE 125
                 +   +  SY+D             RV F  +        I   ++   DT TY 
Sbjct: 69  TTRLVCYNNKITASYED-------------RVTFLPT-------GITFKSVTREDTGTYT 108

Query: 126 CRVKK---TTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAK 182
           C V +    +    KV + V   P+ P        T GN  VL C    GS P  Y W K
Sbjct: 109 CMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFK 168

Query: 183 ISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVA 242
             G   P             +  S +   +SS       G+LV   +S +D G Y C   
Sbjct: 169 -DGIVMP------------TNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEAR 215

Query: 243 NNVGYSVCVVEVKV-SDSRRIGVIIGIVLGSLLALGCLAVGIW 284
           N  G  +    V++ +  R +GVI+  VL +L+ LG L  GIW
Sbjct: 216 NGYGTPMTSNAVRMEAVERNVGVIVAAVLVTLILLGILVFGIW 258


>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
           sapiens]
          Length = 387

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 68/275 (24%), Positives = 125/275 (45%), Gaps = 48/275 (17%)

Query: 9   LLLVCLSPALLSAVRIN-GDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNS 67
           L+L CL+   +S V++   DG   + +  G NV L C Y           L I+W     
Sbjct: 10  LILSCLA-GQVSVVQVTIPDG--FVNVTVGSNVTLICIYTTTVASR--EQLSIQWSFF-- 62

Query: 68  DPAHHRE----NVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTAT 123
              H +E    +++ S   + +  G     + R+   ++DP   +ASI + ++Q +D+  
Sbjct: 63  ---HKKEMEPISIYFSQGGQAVAIGQF---KDRIT-GSNDPG--NASITISHMQPADSGI 113

Query: 124 YECRVKKTT--MATRKVI--VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYK 179
           Y C V      +   + I  V+V  +P+ P+C  +G    G+ + L C ++ G+    Y 
Sbjct: 114 YICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYY 173

Query: 180 WAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQC 239
           W K+ G                   +  +E+F+ +       G LV+ +++  + G YQC
Sbjct: 174 WHKLEGRDI----------------VPVKENFNPT------TGILVIGNLTNFEQGYYQC 211

Query: 240 TVANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLL 274
           T  N +G S C +++  S    +G+I+G ++GSL+
Sbjct: 212 TAINRLGNSSCEIDL-TSSHPEVGIIVGALIGSLV 245


>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
          Length = 355

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 76/310 (24%), Positives = 114/310 (36%), Gaps = 45/310 (14%)

Query: 10  LLVCLSPALLSAVRINGDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDP 69
           LL+     L+ AV +    +  + + E ++V L C  + D +   P    IEW ++  + 
Sbjct: 65  LLLLFRGCLIGAVNLKSSNRTPV-VQEFESVELSC-IITDSQTSDPR---IEWKKIQDEQ 119

Query: 70  AHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVK 129
             +   VF    D +I       L  R             S+ + N+   D+A Y C V 
Sbjct: 120 TTY---VFF---DNKIQGD----LAGRAEILGK------TSLKIWNVTRRDSALYRCEV- 162

Query: 130 KTTMATRKVI------VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKI 183
                 RK I      +TVQ +P  P+C     +  G    L C  S G     Y W + 
Sbjct: 163 -VARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR- 220

Query: 184 SGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVAN 243
             +  P    S  +    +S      SFH +       G LV   + + D G Y C  +N
Sbjct: 221 --NDVPLPTDSRANPRFRNS------SFHLNSE----TGTLVFTAVHKDDSGQYYCIASN 268

Query: 244 NVGYSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGGSGAGGARGAF 303
           + G + C  +        IG IIG   G L+ L  LA+   G+ C    G      +   
Sbjct: 269 DAGSARCEEQEMEVYDLNIGGIIG---GVLVVLAVLALITLGICCAYRRGYFINNKQDGE 325

Query: 304 GYGNGGGVGG 313
            Y N G   G
Sbjct: 326 SYKNPGKPDG 335


>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
          Length = 298

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 50/179 (27%), Positives = 70/179 (39%), Gaps = 23/179 (12%)

Query: 108 DASINLMNLQVSDTATYECRVKKTT-----MATRKVIVTVQARPAVPMCWTEGHMTYGND 162
           D +I + N+  SD   Y C V   +     +    V + V   PAVP C        G  
Sbjct: 91  DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTV 150

Query: 163 VVLKCYASGGSQPLSYKWAK--ISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLN 220
           V L+C    G+    Y W K  I     P R GS              +S +SS      
Sbjct: 151 VELRCQDKEGNPAPEYTWFKDGIRLLENP-RLGS--------------QSTNSSYTMNTK 195

Query: 221 NGDLVLKDISRADDGLYQCTVANNVGYSVCV-VEVKVSDSRRIGVIIGIVLGSLLALGC 278
            G L    +S+ D G Y C   N+VGY  C    ++V D    G+I  +V+ +L+   C
Sbjct: 196 TGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNISGIIAAVVVVALVISVC 254


>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
          Length = 354

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 53/213 (24%), Positives = 85/213 (39%), Gaps = 44/213 (20%)

Query: 98  RFAASDPSQYDASINLMNLQVSDTATYECRVK-KTTMATRKVIVTVQARPAVPMCWTEGH 156
           R + S  ++ D S+ + N+ V+D   Y C V+ + T  T +V +TVQ  P +     +  
Sbjct: 90  RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMT 149

Query: 157 MTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSIN 216
           +  G +V L C A+G  +P S  W  IS    P+  G Y                     
Sbjct: 150 VNEGTNVTLTCLATGKPEP-SISWRHISPSAKPFENGQY--------------------- 187

Query: 217 QGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIV-LGSLLA 275
                  L +  I+R   G Y+C+  N+V +          D R++ V++        + 
Sbjct: 188 -------LDIYGITRDQAGEYECSAENDVSF---------PDVRKVKVVVNFAPTIQEIK 231

Query: 276 LGCLAVGIWGLVCCCCGGSGAGGARGAFGYGNG 308
            G +  G  GL+ C     GAG    AF +  G
Sbjct: 232 SGTVTPGRSGLIRC----EGAGVPPPAFEWYKG 260


>gi|37700249 HEPACAM family member 2 isoform 2 [Homo sapiens]
          Length = 450

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 45/215 (20%)

Query: 85  INHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVK----KTTMATRKVIV 140
           +N   +P L+ + +F    P+   AS+ +  LQ  D   Y  +V      T  A++K+ V
Sbjct: 72  VNKSVVPDLEYQHKFTMMPPN---ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQV 128

Query: 141 TVQ---ARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTS 197
           TV     +P V +    G + Y  ++ L C+  GG++ L+Y+W K              +
Sbjct: 129 TVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTR-LAYQWLK--------------N 173

Query: 198 QHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVG----------- 246
               H+  +Y  S          N  L +  +++ D G Y C V N V            
Sbjct: 174 GRPVHTSSTYSFS--------PQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPII 225

Query: 247 -YSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLA 280
            Y    ++V      ++G +  + LG  +   C A
Sbjct: 226 YYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSA 260


>gi|86439957 HEPACAM family member 2 isoform 1 [Homo sapiens]
          Length = 462

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 49/215 (22%), Positives = 85/215 (39%), Gaps = 45/215 (20%)

Query: 85  INHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVK----KTTMATRKVIV 140
           +N   +P L+ + +F    P+   AS+ +  LQ  D   Y  +V      T  A++K+ V
Sbjct: 84  VNKSVVPDLEYQHKFTMMPPN---ASLLINPLQFPDEGNYIVKVNIQGNGTLSASQKIQV 140

Query: 141 TVQ---ARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTS 197
           TV     +P V +    G + Y  ++ L C+  GG++ L+Y+W K              +
Sbjct: 141 TVDDPVTKPVVQIHPPSGAVEYVGNMTLTCHVEGGTR-LAYQWLK--------------N 185

Query: 198 QHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVG----------- 246
               H+  +Y  S          N  L +  +++ D G Y C V N V            
Sbjct: 186 GRPVHTSSTYSFS--------PQNNTLHIAPVTKEDIGNYSCLVRNPVSEMESDIIMPII 237

Query: 247 -YSVCVVEVKVSDSRRIGVIIGIVLGSLLALGCLA 280
            Y    ++V      ++G +  + LG  +   C A
Sbjct: 238 YYGPYGLQVNSDKGLKVGEVFTVDLGEAILFDCSA 272


>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
          Length = 316

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 40/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           L  RV   ++  +QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 84  LDPRVVLLSNTQTQY--SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI 141

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  GN++ L C A+G  +P       ++  H   +A  + S+  Y          
Sbjct: 142 SSDISINEGNNISLTCIATGRPEP------TVTWRHISPKAVGFVSEDEY---------- 185

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV--------SDSRRIG 263
                       L ++ I+R   G Y+C+ +N+V   V V  VKV        S+++  G
Sbjct: 186 ------------LEIQGITREQSGDYECSASNDVAAPV-VRRVKVTVNYPPYISEAKGTG 232

Query: 264 VIIG 267
           V +G
Sbjct: 233 VPVG 236


>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
          Length = 355

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 40/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           L  RV   ++  +QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 84  LDPRVVLLSNTQTQY--SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI 141

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  GN++ L C A+G  +P       ++  H   +A  + S+  Y          
Sbjct: 142 SSDISINEGNNISLTCIATGRPEP------TVTWRHISPKAVGFVSEDEY---------- 185

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV--------SDSRRIG 263
                       L ++ I+R   G Y+C+ +N+V   V V  VKV        S+++  G
Sbjct: 186 ------------LEIQGITREQSGDYECSASNDVAAPV-VRRVKVTVNYPPYISEAKGTG 232

Query: 264 VIIG 267
           V +G
Sbjct: 233 VPVG 236


>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
          Length = 344

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 40/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           L  RV   ++  +QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 84  LDPRVVLLSNTQTQY--SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI 141

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  GN++ L C A+G  +P       ++  H   +A  + S+  Y          
Sbjct: 142 SSDISINEGNNISLTCIATGRPEP------TVTWRHISPKAVGFVSEDEY---------- 185

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV--------SDSRRIG 263
                       L ++ I+R   G Y+C+ +N+V   V V  VKV        S+++  G
Sbjct: 186 ------------LEIQGITREQSGDYECSASNDVAAPV-VRRVKVTVNYPPYISEAKGTG 232

Query: 264 VIIG 267
           V +G
Sbjct: 233 VPVG 236


>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
          Length = 344

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 40/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           L  RV   ++  +QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 84  LDPRVVLLSNTQTQY--SIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEI 141

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  GN++ L C A+G  +P       ++  H   +A  + S+  Y          
Sbjct: 142 SSDISINEGNNISLTCIATGRPEP------TVTWRHISPKAVGFVSEDEY---------- 185

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV--------SDSRRIG 263
                       L ++ I+R   G Y+C+ +N+V   V V  VKV        S+++  G
Sbjct: 186 ------------LEIQGITREQSGDYECSASNDVAAPV-VRRVKVTVNYPPYISEAKGTG 232

Query: 264 VIIG 267
           V +G
Sbjct: 233 VPVG 236


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 26/155 (16%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVIV-TVQARPAVPMCWTEGH----MTYGND 162
            + ++ + NL  SD  TYEC    +T + R+V++ T++ R   P           + +G+ 
Sbjct: 1899 NGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDK 1958

Query: 163  VVLKCYASGGSQP-LSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNN 221
            ++L C A+G  +P + ++    +     +R GS+   H Y                   N
Sbjct: 1959 LLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWI--HVYP------------------N 1998

Query: 222  GDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
            G L +  ++  D G+Y C   N +G  + ++ V +
Sbjct: 1999 GSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSL 2033



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 44/186 (23%), Positives = 74/186 (39%), Gaps = 31/186 (16%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHM----TYGNDV 163
            D ++ L NL + D   Y+C V         ++V +Q   A P+   +       T+G  +
Sbjct: 1802 DGTLVLHNLSIYDRGFYKC-VASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESL 1860

Query: 164  VLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGD 223
             L C A G  QP  Y W    G                 +E+   +  +S +    +NG 
Sbjct: 1861 KLPCTAKGTPQPSVY-WVLSDG-----------------TEVKPLQFTNSKLFL-FSNGT 1901

Query: 224  LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD---SRRIGVI----IGIVLGSLLAL 276
            L +++++ +D G Y+C   ++ G    VV + + +   S RI         +  G  L L
Sbjct: 1902 LYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLL 1961

Query: 277  GCLAVG 282
             C A G
Sbjct: 1962 NCSATG 1967



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 41/186 (22%), Positives = 75/186 (40%), Gaps = 31/186 (16%)

Query: 108  DASINLMNLQVSDTATYECRVK----KTTMATRKVIVTVQARPAVPMCWTEGHMTY-GND 162
            + ++ + N+++SD+A + C  +    ++ +  +  ++ +  RP     + E  +   G  
Sbjct: 2295 NGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKS 2354

Query: 163  VVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNG 222
              L C   G   P    W   +G  +             +   SYQ    S       NG
Sbjct: 2355 TALNCSVDGNPPP-EIIWILPNGTRFS------------NGPQSYQYLIAS-------NG 2394

Query: 223  DLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRI-----GVIIGIVLGSLLALG 277
              ++   +R D G Y+C   N VGY   +V +++     I     G + GI  G  L+L 
Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGI-SGESLSLH 2453

Query: 278  CLAVGI 283
            C++ GI
Sbjct: 2454 CVSDGI 2459



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 39/173 (22%), Positives = 66/173 (38%), Gaps = 31/173 (17%)

Query: 120  DTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMT--YGNDVVLKCYASGGSQPLS 177
            D   Y C  +       K+++    +  V + +  G +    G  + L C + G  +P +
Sbjct: 2405 DAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKP-N 2463

Query: 178  YKWAKISGH--HYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDG 235
             KW   SG+    P   G Y                        +NG LV+K+ +  D G
Sbjct: 2464 IKWTMPSGYVVDRPQINGKYILH---------------------DNGTLVIKEATAYDRG 2502

Query: 236  LYQCTVANNVGYSVCVVEVKV-----SDSRRIGVIIGIVLGSLLALGCLAVGI 283
             Y C   N+VG+++  V V +       + R    I    G+   L C+A+G+
Sbjct: 2503 NYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGV 2555



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 44/185 (23%), Positives = 74/185 (40%), Gaps = 31/185 (16%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWT----EGHMTYGNDV 163
            + ++++  +++ D   Y C        T  + VT+      P        E  +  G+ V
Sbjct: 1705 NGTLSIQRVEIQDRGQYLCSASNL-FGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTV 1763

Query: 164  VLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGD 223
             LKC A G   P +  W   +         S +SQ S  + ++              +G 
Sbjct: 1764 ELKCRAEGRPSP-TVTWILAN-----QTVVSESSQGSRQAVVTV-------------DGT 1804

Query: 224  LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS------RRIGVIIGIVLGSLLALG 277
            LVL ++S  D G Y+C  +N  G    +V+++V  +      +R  VI+G   G  L L 
Sbjct: 1805 LVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVG-TWGESLKLP 1863

Query: 278  CLAVG 282
            C A G
Sbjct: 1864 CTAKG 1868



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 207 YQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
           YQ S    +   LNNG L +  ++  D G Y+C  AN  G    + +V V
Sbjct: 616 YQSSRDKKV---LNNGTLRILQVTPKDQGYYRCVAANPSGVDFLIFQVSV 662



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 221 NGDLVLKDISRADDGLYQCTVANN-----VGYSVCVVEVKVSDSRRIGVIIGIVLGSLLA 275
           +G L L+     D G+Y C  +N      + Y + VVE  V   +  G+   + +G  L 
Sbjct: 533 SGKLELQMADSFDTGVYHCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLD 592

Query: 276 LGCLAVGI 283
           L C + GI
Sbjct: 593 LPCHSTGI 600



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 202  HSELSY--QESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
            HS LS   +E  H S    L  G LV+++   +D G+Y+CT  N +G       ++V
Sbjct: 2567 HSLLSTASKERTHGSEQLHLQ-GTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 33/154 (21%), Positives = 61/154 (39%), Gaps = 20/154 (12%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVI--VTVQARPAV--PMCWTEGHMTYGNDV 163
            + S+ + ++   D+  Y C V +  M    ++  V+++ +PA      +    + +G D 
Sbjct: 1998 NGSLFIGSVTEKDSGVYLC-VARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDF 2056

Query: 164  VLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGL-NNG 222
             + C ASG   P    W+   G                ++ +   +S H +    L NNG
Sbjct: 2057 QVDCKASGSPVP-EISWSLPDGT-------------MINNAMQADDSGHRTRRYTLFNNG 2102

Query: 223  DLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
             L    +  A++G Y C   N +G     V + V
Sbjct: 2103 TLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTV 2136


>gi|19743806 roundabout 1 isoform b [Homo sapiens]
          Length = 1612

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 25/176 (14%)

Query: 84  RINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT-MATRKVIVTV 142
           R + G LP  +  +R         D ++ +  +   D  +Y C  +     A     +TV
Sbjct: 257 RKDDGELPKSRYEIRD--------DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308

Query: 143 QARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYH 202
           Q  P   +   +  +  G  V  +C A+G  QP  + W          R GS     SY 
Sbjct: 309 QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIF-WR---------REGSQNLLFSYQ 358

Query: 203 SELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
                Q S   S++Q    GDL + ++ R+D G Y C   N  G  +    ++V+D
Sbjct: 359 PP---QSSSRFSVSQ---TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 408


>gi|4506569 roundabout 1 isoform a [Homo sapiens]
          Length = 1651

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 43/176 (24%), Positives = 69/176 (39%), Gaps = 25/176 (14%)

Query: 84  RINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT-MATRKVIVTV 142
           R + G LP  +  +R         D ++ +  +   D  +Y C  +     A     +TV
Sbjct: 296 RKDDGELPKSRYEIRD--------DHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347

Query: 143 QARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYH 202
           Q  P   +   +  +  G  V  +C A+G  QP  + W          R GS     SY 
Sbjct: 348 QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIF-WR---------REGSQNLLFSYQ 397

Query: 203 SELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
                Q S   S++Q    GDL + ++ R+D G Y C   N  G  +    ++V+D
Sbjct: 398 PP---QSSSRFSVSQ---TGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 447


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
           precursor [Homo sapiens]
          Length = 2012

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/150 (26%), Positives = 59/150 (39%), Gaps = 22/150 (14%)

Query: 103 DPSQYDASINLMNLQVSDTATYECRVKKTTMATR---KVIVTVQARPAVPMCWTEGHMTY 159
           D   + +S+ + NL +     Y C  +    A     ++IV V  +  V     +G   Y
Sbjct: 646 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDG--IY 703

Query: 160 GNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGL 219
           G  V+L C A G   P +  W    G   P                 +Q    +   Q L
Sbjct: 704 GKAVILNCSAEGYPVP-TIVWKFSKGAGVP----------------QFQPIALNGRIQVL 746

Query: 220 NNGDLVLKDISRADDGLYQCTVANNVGYSV 249
           +NG L++K +   D G Y C V+N+VG  V
Sbjct: 747 SNGSLLIKHVVEEDSGYYLCKVSNDVGADV 776



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 39/162 (24%), Positives = 62/162 (38%), Gaps = 30/162 (18%)

Query: 105  SQYDASINLMNLQV---SDTATYECRVKKTTMATR---KVIVTVQARPAVP--MCWTEGH 156
            S+++AS +  + ++   S    Y   V   T A R     I+TV+     P  +    G 
Sbjct: 1235 SEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGT 1294

Query: 157  MT--YGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSS 214
            +T  +  D+VL C A G   P + KW K S         S  +     S  S        
Sbjct: 1295 VTTPWMKDIVLPCKAVGDPSP-AVKWMKDSNG-----TPSLVTIDGRRSIFS-------- 1340

Query: 215  INQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
                  NG  +++ +   D G Y C   NN G    ++ ++V
Sbjct: 1341 ------NGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQV 1376


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/253 (23%), Positives = 97/253 (38%), Gaps = 64/253 (25%)

Query: 43   GCPYVLDPEDYGPNGLDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAAS 102
            G P  L     G   + ++W++   +     EN+ +++ +              ++FA +
Sbjct: 5624 GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT----------LQFAKA 5673

Query: 103  DPSQYDASINLMNLQVSDTATYECRVK-----KTTMATRKVIV-TVQARPAVPMCWTEGH 156
            +P+              +   Y C++K     +  MAT  V+   V    A PM      
Sbjct: 5674 EPA--------------NAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMT----- 5714

Query: 157  MTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSIN 216
            +T G    L+C  +G  + LS +W         Y+ G   +    H     + SF++ I+
Sbjct: 5715 VTVGETCTLECKVAGTPE-LSVEW---------YKDGKLLTSSQKH-----KFSFYNKIS 5759

Query: 217  QGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD-------SRRIGVIIGIV 269
                   L +  + R D G Y   V NNVG S C   V VSD       +RR+    G V
Sbjct: 5760 S------LRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRL-KNTGGV 5812

Query: 270  LGSLLALGCLAVG 282
            LG+   L C   G
Sbjct: 5813 LGASCILECKVAG 5825



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 40/180 (22%), Positives = 70/180 (38%), Gaps = 24/180 (13%)

Query: 107  YDASINLMNLQVSDTATYECR-VKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVL 165
            +D S++++NL+ SD   Y C+   +    T    V  +  P      ++     G+ V L
Sbjct: 6511 FDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVEL 6570

Query: 166  KCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLV 225
            +     G QP+S  W K  G            + S ++ +S+ +          N   L 
Sbjct: 6571 RAIVE-GFQPISVVWLKDRGE---------VIRESENTRISFID----------NIATLQ 6610

Query: 226  LKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRI---GVIIGIVLGSLLALGCLAVG 282
            L     ++ G Y C + N+ G   C   + V +  RI      + +  G+  AL C+  G
Sbjct: 6611 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTG 6670



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 46/182 (25%), Positives = 74/182 (40%), Gaps = 30/182 (16%)

Query: 109  ASINLMNLQVSDTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKC 167
            A++ L + + S++  Y C++K    M     ++TV     +        +T GN   L+C
Sbjct: 6607 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALEC 6666

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLK 227
              +G  + LS KW K                     ELS     H +    + +  +   
Sbjct: 6667 VVTGTPE-LSAKWFKDG------------------RELSADSKHHITFINKVASLKIPCA 6707

Query: 228  DISRADDGLYQCTVANNVGYSVCVVEVKVSDS-------RRIGVIIGIVLGSLLALGCLA 280
            ++S  D GLY   V N+VG S C V V VSD        R++   +  +LG+ + L C  
Sbjct: 6708 EMS--DKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKL-KDVNAILGASVVLECRV 6764

Query: 281  VG 282
             G
Sbjct: 6765 SG 6766



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 28/157 (17%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGN-DVVLKC 167
            A I + NL   D+  + C  +    +T      +   P V   +     T  N +V L+C
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC 5538

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQ---ESFHSSINQGLNNGDL 224
              SG + P    W              Y  +    S   Y+   ++FH+SI+        
Sbjct: 5539 ELSG-TPPFEVVW--------------YKDKRQLRSSKKYKIASKNFHTSIH-------- 5575

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRR 261
             + ++  +D G Y C   N VG   CV  VK+ +  R
Sbjct: 5576 -ILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPR 5611



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 42/221 (19%), Positives = 74/221 (33%), Gaps = 50/221 (22%)

Query: 42   LGCPYVLDPEDYGPNGLDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAA 101
            +G P V D    G   + + W + +  P     NV  S+ D                   
Sbjct: 8070 VGLPVVFDCAISGSEPISVSWYK-DGKPLKDSPNVQTSFLDNT----------------- 8111

Query: 102  SDPSQYDASINLMNLQVSDTATYECR----VKKTTMATRKVIVTVQARPAVPMCWTEGHM 157
                   A++N+     S    Y C     +   + + R ++   +  P   +       
Sbjct: 8112 -------ATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDA 8164

Query: 158  TYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQ 217
              G     +C+ +G +QP+   WAK S      R+G          ++SY E        
Sbjct: 8165 VVGESADFECHVTG-TQPIKVSWAKDSRE---IRSGG-------KYQISYLE-------- 8205

Query: 218  GLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
              N+  L +  + + D G Y C   N VG   C  ++ + +
Sbjct: 8206 --NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 8244



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 34/145 (23%), Positives = 57/145 (39%), Gaps = 25/145 (17%)

Query: 118  VSDTATYECRVKK---TTMATRKVIVTVQARPAV-PMCWTEGHMTYGNDVVLKCYASGGS 173
            ++D   Y C+V     + + T  +++    +P V     T   ++ G  V L C+  G S
Sbjct: 8314 MNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQG-S 8372

Query: 174  QPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRAD 233
            +P+  +W K      P    S+              SF S          L L+D+++AD
Sbjct: 8373 EPIRIQWLKAGREIKPSDRCSF--------------SFASG------TAVLELRDVAKAD 8412

Query: 234  DGLYQCTVANNVGYSVCVVEVKVSD 258
             G Y C  +N  G      +V + D
Sbjct: 8413 SGDYVCKASNVAGSDTTKSKVTIKD 8437



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 38/177 (21%), Positives = 66/177 (37%), Gaps = 24/177 (13%)

Query: 110  SINLMNLQVSDTATYECRVKKTTMATRKV-IVTVQARPAVPMCWTEGHMTYGNDVVLKCY 168
            SI+++N+  +D   Y+C+      +   V  + ++A P      ++     G +V L+  
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTT 7514

Query: 169  ASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKD 228
              G ++P+S  W K  G            + S +  +SY E          N   L    
Sbjct: 7515 IEG-AEPISVVWFKDKGE---------IVRESDNIWISYSE----------NIATLQFSR 7554

Query: 229  ISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRI---GVIIGIVLGSLLALGCLAVG 282
            +  A+ G Y C + N+ G   C   + V +   I      I +  G    L C   G
Sbjct: 7555 VEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAG 7611



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 39/206 (18%), Positives = 75/206 (36%), Gaps = 46/206 (22%)

Query: 54   GPNGLDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINL 113
            G   + + W +   +     +N+++SY                        S+  A++  
Sbjct: 7517 GAEPISVVWFKDKGEIVRESDNIWISY------------------------SENIATLQF 7552

Query: 114  MNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWTEG-HMTYGNDVVLKCYASGG 172
              ++ ++   Y C++K                PA  +   E   +T G+   L+C  +G 
Sbjct: 7553 SRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGT 7612

Query: 173  SQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRA 232
             + LS KW K                    S+  Y+ SF + ++       L + +++ +
Sbjct: 7613 PE-LSTKWFK--------------DGKELTSDNKYKISFFNKVS------GLKIINVAPS 7651

Query: 233  DDGLYQCTVANNVGYSVCVVEVKVSD 258
            D G+Y   V N VG   C   ++VSD
Sbjct: 7652 DSGVYSFEVQNPVGKDSCTASLQVSD 7677



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 35/154 (22%), Positives = 54/154 (35%), Gaps = 22/154 (14%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTM-ATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKC 167
            A + +      D+  Y C        A+    +TV+A P      +      G+DV+L+C
Sbjct: 6420 ALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQC 6479

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLK 227
              S G+ P    W K        +    TS+H       +  S H             + 
Sbjct: 6480 EIS-GTPPFEVVWVKDRKQVRNSKKFKITSKH-------FDTSLH-------------IL 6518

Query: 228  DISRADDGLYQCTVANNVGYSVCVVEVKVSDSRR 261
            ++  +D G Y C   N VG   C   VK  +  R
Sbjct: 6519 NLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPR 6552



 Score = 35.4 bits (80), Expect = 0.096
 Identities = 36/147 (24%), Positives = 53/147 (36%), Gaps = 28/147 (19%)

Query: 109  ASINLMNLQVSDTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKC 167
            A + + NL V D+  Y C        A+    + V+  P             G DV L+C
Sbjct: 7361 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLEC 7420

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQ---ESFHSSINQGLNNGDL 224
               G + P    W              Y  +    S   Y+   E+F +SI+        
Sbjct: 7421 ELQG-TPPFHVSW--------------YKDKRELRSGKKYKIMSENFLTSIH-------- 7457

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCV 251
             + ++  AD G YQC   N+VG   CV
Sbjct: 7458 -ILNVDAADIGEYQCKATNDVGSDTCV 7483



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 15/50 (30%), Positives = 29/50 (58%)

Query: 210   SFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS 259
             S H ++++  ++  L++KD++R D G Y  T  N+ G     ++V V D+
Sbjct: 18942 SSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 18991



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 23/99 (23%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 160  GNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGL 219
            G+ + L+C  +G S P+S +W K                    +   Y+ SFH       
Sbjct: 4689 GSFIDLECIVAG-SHPISIQWFK--------------DDQEISASEKYKFSFHD------ 4727

Query: 220  NNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
            N   L +  +   D G Y C+  N  G++ C   + V +
Sbjct: 4728 NTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 4766



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 204   ELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRI 262
             +L   E +  +   G+    L +KDI++ DDG Y+C V N+ G      E+ V   R +
Sbjct: 31608 QLENSEKYEITYEDGV--AILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREV 31664



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 30/145 (20%), Positives = 56/145 (38%), Gaps = 22/145 (15%)

Query: 108  DASINLMNLQVSDTATYECR-VKKTTMATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
            +A +++ +++V D+ +Y C  V      +    + ++  P+         +  G + +L+
Sbjct: 3792 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQ 3851

Query: 167  CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
            C  SG + P    W K               +    S   Y+     S+        L +
Sbjct: 3852 CEVSG-TGPFEISWFK--------------DKKQIRSSKKYRLFSQKSLVC------LEI 3890

Query: 227  KDISRADDGLYQCTVANNVGYSVCV 251
               + AD G Y+C VAN VG   C+
Sbjct: 3891 FSFNSADVGEYECVVANEVGKCGCM 3915



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 35/155 (22%), Positives = 57/155 (36%), Gaps = 22/155 (14%)

Query: 105  SQYDASINLMNLQVSDTATYECRVKKTTMATR-KVIVTVQARPAVPMCWTEGHMTYGNDV 163
            S+   ++NL  L+ SDT  Y C       +     ++TVQ  P+         +  G  +
Sbjct: 6792 SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSL 6851

Query: 164  VLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGD 223
                    G+ P   KW K S                   EL   ES + S+   +   +
Sbjct: 6852 TFTSVIR-GTPPFKVKWFKGS------------------RELVPGESCNISLEDFVT--E 6890

Query: 224  LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
            L L ++   + G Y C V N+ G + C   + V +
Sbjct: 6891 LELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE 6925



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 24/101 (23%), Positives = 42/101 (41%), Gaps = 23/101 (22%)

Query: 160  GNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGL 219
            G  V L+C+ SG   P +  W              Y   +   S + +Q +F S I +  
Sbjct: 957  GESVTLECHISGYPSP-TVTW--------------YREDYQIESSIDFQITFQSGIAR-- 999

Query: 220  NNGDLVLKDISRADDGLYQCTVANNVG--YSVCVVEVKVSD 258
                L++++    D G + C+  N  G   + C + V+VS+
Sbjct: 1000 ----LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 15/36 (41%), Positives = 21/36 (58%)

Query: 224   LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS 259
             LV+ +++R D G Y  T+ NN G     V V+V DS
Sbjct: 25163 LVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDS 25198



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 23/99 (23%), Positives = 39/99 (39%), Gaps = 21/99 (21%)

Query: 160  GNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGL 219
            G     +C+ +G +QP+   W+K +    P   G+YT                  I    
Sbjct: 6285 GESADFECHVTG-AQPMRITWSKDNKEIRP--GGNYT------------------ITCVG 6323

Query: 220  NNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
            N   L +  + + D G Y C   N+VG  +C  ++ V +
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE 6362



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 21/104 (20%)

Query: 158  TYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQ 217
            T GN   L+   +G SQP++  W                    Y + +  Q + +  I  
Sbjct: 8262 TEGNSFKLEGRVAG-SQPITVAW--------------------YKNNIEIQPTSNCEITF 8300

Query: 218  GLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRR 261
              N   L ++     D GLY C V+N+ G ++C   + + + ++
Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKK 8344



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 29/156 (18%), Positives = 55/156 (35%), Gaps = 22/156 (14%)

Query: 105  SQYDASINLMNLQVSDTATYECRVKKT--TMATRKVIVTVQARPAVPMCWTEGHMTYGND 162
            S+Y +S+ ++  QV D   Y C+      +++    +   +A P   +   +   T+   
Sbjct: 3507 SKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGK 3566

Query: 163  VVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNG 222
                     G+  +   W K      P                    S +  I+   N  
Sbjct: 3567 AAKFICTVTGTPVIETIWQKDGAALSP--------------------SPNWRISDAENKH 3606

Query: 223  DLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             L L +++  D G+Y C  +N  G  +C  E+ + D
Sbjct: 3607 ILELSNLTIQDRGVYSCKASNKFGADICQAELIIID 3642



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 41/184 (22%), Positives = 73/184 (39%), Gaps = 34/184 (18%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTMATR-KVIVTVQARPAVPMCWTEGHMTYGNDVVLKC 167
            AS+ L  ++V     Y C+ K      R   +++V+    +        +T G+   L+ 
Sbjct: 4541 ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQV 4600

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLK 227
              SG ++ ++ KW K                     EL+    +  S+   ++    +LK
Sbjct: 4601 KFSG-TKEITAKWFKDG------------------QELTLGSKYKISVTDTVS----ILK 4637

Query: 228  DIS--RADDGLYQCTVANNVGYSVCVVEVKVSD-------SRRIGVIIGIVLGSLLALGC 278
             IS  + D G Y   V N+VG S C   + V D       ++++  +  I  GS + L C
Sbjct: 4638 IISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSI-KGSFIDLEC 4696

Query: 279  LAVG 282
            +  G
Sbjct: 4697 IVAG 4700



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 35/154 (22%), Positives = 57/154 (37%), Gaps = 25/154 (16%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWT----EGHMTYGNDVV 164
            AS+ +   ++SD   Y   VK +   +   +    +   VP  +     + +   G  VV
Sbjct: 6700 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVV 6759

Query: 165  LKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDL 224
            L+C  SG S P+S  W              +   +   S    Q SF  ++        L
Sbjct: 6760 LECRVSG-SAPISVGW--------------FQDGNEIVSGPKCQSSFSENVCT------L 6798

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             L  +  +D G+Y C  AN  G   C   + V +
Sbjct: 6799 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 6832



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
            +LK ++ AD G YQC V N VG S+C   V + +
Sbjct: 4452 ILKFVA-ADAGEYQCRVTNEVGSSICSARVTLRE 4484



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 35/154 (22%), Positives = 52/154 (33%), Gaps = 23/154 (14%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPA--VPMCWTEGHMTYGNDVVL 165
            ++S+ L  ++ SD+ TY C+V                 PA  V        +  G+   L
Sbjct: 4260 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQL 4319

Query: 166  KCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLV 225
             C  +G + P+   W           A     + S    +S+ ES             L 
Sbjct: 4320 ACKVTG-TPPIKITWF----------ANDREIKESSKHRMSFVES----------TAVLR 4358

Query: 226  LKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS 259
            L D+   D G Y C   N  G   C   V V +S
Sbjct: 4359 LTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392



 Score = 30.4 bits (67), Expect = 3.1
 Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 34/168 (20%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMCW----TEGHMTYGND- 162
            A + L ++  +D+  Y C+      + T K  VT++ +PAV         +G + + ++ 
Sbjct: 8401 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEP 8460

Query: 163  ----VVLKCYAS-----GGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHS 213
                VV K  A+     GG    + KW K          G +   +         +    
Sbjct: 8461 QSIRVVEKTTATFIAKVGGDPIPNVKWTK----------GKWRQLN---------QGGRV 8501

Query: 214  SINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRR 261
             I+Q  +   L ++D ++ D GLY+C   N  G     V ++V + ++
Sbjct: 8502 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKK 8549



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 15/36 (41%), Positives = 20/36 (55%)

Query: 223   DLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             +LV KD +R D G Y  T  N  G++  +  VKV D
Sbjct: 21518 NLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLD 21553



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 31/154 (20%), Positives = 57/154 (37%), Gaps = 25/154 (16%)

Query: 109  ASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPAVPMCWT----EGHMTYGNDVV 164
            + + ++N+  SD+  Y   V+              +   VP  +T    E +   G+ VV
Sbjct: 7641 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVV 7700

Query: 165  LKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDL 224
            ++C   G S P+S  W         +  G+         E+S    + +++    N   L
Sbjct: 7701 MECKVYG-SPPISVSW---------FHEGN---------EISSGRKYQTTLTD--NTCAL 7739

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             +  +  +D G Y C   N  G   C   + V +
Sbjct: 7740 TVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE 7773



 Score = 29.3 bits (64), Expect = 6.9
 Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 5/83 (6%)

Query: 204   ELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIG 263
             E+  +E+   SI    +   L +KD  R D G Y  T+ N  G     V V V    R G
Sbjct: 28685 EMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG--RPG 28742

Query: 264   VIIG-IVLGSLLALGCLAVGIWG 285
              + G I + S+ A  C  V  WG
Sbjct: 28743 PVTGPIEVSSVSAESC--VLSWG 28763



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 11/35 (31%), Positives = 17/35 (48%)

Query: 224  LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
            L + D+   D G Y C   N+VG   C  E+ + +
Sbjct: 3795 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE 3829



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 36/169 (21%), Positives = 58/169 (34%), Gaps = 37/169 (21%)

Query: 88   GSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMATRKVIVTVQARPA 147
            G+ PHL+  ++    D  QY       N    D  + +  VK+     +K+  +  A+  
Sbjct: 6323 GNTPHLRI-LKVGKGDSGQYTCQAT--NDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQ- 6378

Query: 148  VPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSY 207
                        G  + L+C  SG S  +   W              + +    H    Y
Sbjct: 6379 ------------GESIQLECKISG-SPEIKVSW--------------FRNDSELHESWKY 6411

Query: 208  QESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKV 256
              SF +S+        L + + S  D G Y C   N VG + C   + V
Sbjct: 6412 NMSFINSVAL------LTINEASAEDSGDYICEAHNGVGDASCSTALTV 6454



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 13/36 (36%), Positives = 18/36 (50%)

Query: 223   DLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             +L++KD  R D G Y  T  N+ G       V+V D
Sbjct: 15160 ELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFD 15195



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 224   LVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS 259
             LVL +++R D G Y  T+ N+ G     V V+V D+
Sbjct: 22998 LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 23033



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 15/54 (27%), Positives = 26/54 (48%)

Query: 205   LSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSD 258
             L  +++   ++   L+   L +K+  + D G Y  TVAN VG     +E+   D
Sbjct: 23268 LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLD 23321


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/180 (22%), Positives = 66/180 (36%), Gaps = 28/180 (15%)

Query: 108 DASINLMNLQVSDTATYECRVKKTTMATR-KVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
           D S+ +  +  +D   Y+C        TR  V + V+  P V +  +  H + G +V + 
Sbjct: 452 DLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVS 511

Query: 167 CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
           C ASG   P           H  +   S   Q      +  Q             G L++
Sbjct: 512 CSASGYPTP-----------HISWSRESQALQEDSRIHVDAQ-------------GTLII 547

Query: 227 KDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIVL---GSLLALGCLAVGI 283
           + ++  D G Y C   N VG     V +  +D   +  +  +VL   G    L C A G+
Sbjct: 548 QGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGV 607



 Score = 35.8 bits (81), Expect = 0.073
 Identities = 38/156 (24%), Positives = 55/156 (35%), Gaps = 24/156 (15%)

Query: 108 DASINLMNLQVSDTATYECRVKKTTMAT-RKVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
           D S++L          Y C    T  +  R V + VQ  P +    T      G    L 
Sbjct: 820 DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLP 879

Query: 167 CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
           C ASG   P +  W K           + TS+  +++                  G L++
Sbjct: 880 CVASGVPAP-TITWTK--------ETNALTSRGPHYNVSK--------------EGTLLI 916

Query: 227 KDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRI 262
              S  D G Y CT  N VG+S   + + V+   RI
Sbjct: 917 AQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRI 952


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/180 (22%), Positives = 66/180 (36%), Gaps = 28/180 (15%)

Query: 108 DASINLMNLQVSDTATYECRVKKTTMATR-KVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
           D S+ +  +  +D   Y+C        TR  V + V+  P V +  +  H + G +V + 
Sbjct: 569 DLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVS 628

Query: 167 CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
           C ASG   P           H  +   S   Q      +  Q             G L++
Sbjct: 629 CSASGYPTP-----------HISWSRESQALQEDSRIHVDAQ-------------GTLII 664

Query: 227 KDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIVL---GSLLALGCLAVGI 283
           + ++  D G Y C   N VG     V +  +D   +  +  +VL   G    L C A G+
Sbjct: 665 QGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGV 724



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 39/139 (28%), Positives = 52/139 (37%), Gaps = 24/139 (17%)

Query: 111  INLMNLQVSDTATYECRVKKTTMATRK-VIVTVQARPAVPMCWT--EGHMTYGNDVVLKC 167
            + L  LQ +   TY C  + T    RK  +V V   P +       E H+  G +V L C
Sbjct: 3180 LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDC 3239

Query: 168  YASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLK 227
             A G   P    W K          GS   Q     ++     F+      L+ G LVLK
Sbjct: 3240 EADGQPPP-DVAWLK---------DGSPLGQ-----DMGPHLRFY------LDGGSLVLK 3278

Query: 228  DISRADDGLYQCTVANNVG 246
             +  +D G Y C   N  G
Sbjct: 3279 GLRASDAGAYTCVAHNPAG 3297



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 27/179 (15%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMATRKVIVTV-QARPAVPMCWTEGHMTYGNDVVLK 166
            + S+ +   +  D   Y+C  +      +KV++ V Q+ P   +   +  +  G+DV L+
Sbjct: 4270 NGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALR 4329

Query: 167  CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
            C A+G   P + +W +      P RA                    S   + L +G L L
Sbjct: 4330 CQATGEPTP-TIEWLQAG---QPLRA--------------------SRRLRTLPDGSLWL 4365

Query: 227  KDISRADDGLYQCTVANNVGYSV--CVVEVKVSDSRRIGVIIGIVLGSLLALGCLAVGI 283
            +++   D G Y C   N +G +     + V+       G + G++ G    +  L   +
Sbjct: 4366 ENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVINGRKFGVATLNTSV 4424



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 34/137 (24%), Positives = 50/137 (36%), Gaps = 24/137 (17%)

Query: 111  INLMNLQVSDTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYA 169
            + + +    D   Y C  K +   A  K  + VQ  P +     +   T G+   L C A
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061

Query: 170  SGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDI 229
             G  +P +  W K  G       G +T Q S                     G+L++K++
Sbjct: 4062 RGSPEP-NITWDK-DGQPVSGAEGKFTIQPS---------------------GELLVKNL 4098

Query: 230  SRADDGLYQCTVANNVG 246
               D G Y CT  N VG
Sbjct: 4099 EGQDAGTYTCTAENAVG 4115



 Score = 35.4 bits (80), Expect = 0.096
 Identities = 47/202 (23%), Positives = 71/202 (35%), Gaps = 28/202 (13%)

Query: 108  DASINLMNLQVSDTATYECRVKKTTMAT-RKVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
            D S++L          Y C    T  +  R V + VQ  P +    T      G    L 
Sbjct: 937  DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLP 996

Query: 167  CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
            C ASG   P +  W K           + TS+  +++                  G L++
Sbjct: 997  CVASGVPAP-TITWTK--------ETNALTSRGPHYNVSK--------------EGTLLI 1033

Query: 227  KDISRADDGLYQCTVANNVGYSVCVVEVKVSD---SRRIGVIIGIVLGSLLALGCLAVGI 283
               S  D G Y CT  N VG+S   + + V+    S+ +    G++    L L  + VG 
Sbjct: 1034 AQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGD 1093

Query: 284  WG-LVCCCCGGSGAGGARGAFG 304
             G   C     +G+   R   G
Sbjct: 1094 SGHYECTASNPAGSASHRYVLG 1115



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 35/155 (22%), Positives = 54/155 (34%), Gaps = 26/155 (16%)

Query: 106  QYDASINLMNLQVSDTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEGHMTYGNDVV 164
            Q    + + NL+  D  TY C  +     A R+V +T+   P       +  +  G+ + 
Sbjct: 4088 QPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLW 4147

Query: 165  LKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDL 224
            L+C A G   P               R G   +       +S Q+              L
Sbjct: 4148 LRCAARGSPTP---------------RIGWTVNDRPVTEGVSEQD----------GGSTL 4182

Query: 225  VLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDS 259
                +SR D G Y C   N VG +  V  V V ++
Sbjct: 4183 QRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEA 4217



 Score = 32.7 bits (73), Expect = 0.62
 Identities = 35/135 (25%), Positives = 48/135 (35%), Gaps = 25/135 (18%)

Query: 111  INLMNLQVSDTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEG-HMTYGNDVVLKCY 168
            + +   QVSD   Y C+V      A R   +TVQ  P      TE      G+ +VL C 
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD 3147

Query: 169  ASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKD 228
             SG   P +  W K      P  +                 + H  +++G   G L L  
Sbjct: 3148 VSGVPAP-TVTWLK---DRMPVES----------------SAVHGVVSRG---GRLQLSR 3184

Query: 229  ISRADDGLYQCTVAN 243
            +  A  G Y C   N
Sbjct: 3185 LQPAQAGTYTCVAEN 3199



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 42/151 (27%), Positives = 54/151 (35%), Gaps = 30/151 (19%)

Query: 219  LNNGDLVLKDISRADDGLYQCTVANNVGYS------VCVVEVKVSDSRRIGVIIGIVLGS 272
            L  G L L  +S AD G Y+C   N VG +      V  V   + +  R   + G+  G 
Sbjct: 1258 LEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMA-GQ 1316

Query: 273  LLALGCLAVG------IWGLVCCCCGGSGAGGARGAFGYG---NGGGVGGGACGDLASEI 323
             L L C A G      +W            G   G  GYG     G VGG    D    +
Sbjct: 1317 SLTLECDANGFPVPEIVW-----LKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSL 1371

Query: 324  REDAVAPG------CKA---SGRGSRVTHLL 345
                +  G      C+A   +G   R  HLL
Sbjct: 1372 HFPRIQEGDSGLYSCRAENQAGTAQRDFHLL 1402



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 41/168 (24%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 120  DTATYECRVKKTT-MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSY 178
            D+A +EC V      A R   VTV   P +    T+  +T    VVL C+++G   P + 
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAP-TV 3888

Query: 179  KWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQ 238
             W+K +G     R   Y    S   E+      H+                     G Y 
Sbjct: 3889 SWSK-AGAQLGARGSGYRVSPSGALEIGQALPIHA---------------------GRYT 3926

Query: 239  CTVANNVGYSVCVVEVKVSDS---RRIGVIIGIVLGSLLALGCLAVGI 283
            C+  N+ G +   V + V  S   + +  ++  V    + L C A GI
Sbjct: 3927 CSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGI 3974



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 3/73 (4%)

Query: 213  SSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGV---IIGIV 269
            S +   L NG L +    R D G YQC   N +G +  VV + +  +    V    + + 
Sbjct: 4262 SHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVR 4321

Query: 270  LGSLLALGCLAVG 282
             G  +AL C A G
Sbjct: 4322 SGDDVALRCQATG 4334


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/180 (22%), Positives = 66/180 (36%), Gaps = 28/180 (15%)

Query: 108 DASINLMNLQVSDTATYECRVKKTTMATR-KVIVTVQARPAVPMCWTEGHMTYGNDVVLK 166
           D S+ +  +  +D   Y+C        TR  V + V+  P V +  +  H + G +V + 
Sbjct: 568 DLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVS 627

Query: 167 CYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVL 226
           C ASG   P           H  +   S   Q      +  Q             G L++
Sbjct: 628 CSASGYPTP-----------HISWSRESQALQEDSRIHVDAQ-------------GTLII 663

Query: 227 KDISRADDGLYQCTVANNVGYSVCVVEVKVSDSRRIGVIIGIVL---GSLLALGCLAVGI 283
           + ++  D G Y C   N VG     V +  +D   +  +  +VL   G    L C A G+
Sbjct: 664 QGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGV 723


>gi|59939900 opioid binding protein/cell adhesion molecule-like
           isoform b preproprotein [Homo sapiens]
          Length = 338

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 39/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           +  RV    + P+QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 77  IDPRVIILVNTPTQY--SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 134

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  G+ V L C A G  +P       ++  H   + G       + SE  Y E  
Sbjct: 135 SSDITVNEGSSVTLLCLAIGRPEPT------VTWRHLSVKEGQ-----GFVSEDEYLE-- 181

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVK--------VSDSRRIG 263
                         + DI R   G Y+C+  N+V  +  V +VK        +S ++  G
Sbjct: 182 --------------ISDIKRDQSGEYECSALNDVA-APDVRKVKITVNYPPYISKAKNTG 226

Query: 264 VIIG 267
           V +G
Sbjct: 227 VSVG 230


>gi|4505505 opioid binding protein/cell adhesion molecule-like
           isoform a preproprotein [Homo sapiens]
          Length = 345

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 46/184 (25%), Positives = 74/184 (40%), Gaps = 39/184 (21%)

Query: 93  LQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTTMA-TRKVIVTVQARPAVPMC 151
           +  RV    + P+QY  SI + N+ V D   Y C V+      T +V + VQ  P +   
Sbjct: 84  IDPRVIILVNTPTQY--SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 141

Query: 152 WTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESF 211
            ++  +  G+ V L C A G  +P       ++  H   + G       + SE  Y E  
Sbjct: 142 SSDITVNEGSSVTLLCLAIGRPEPT------VTWRHLSVKEGQ-----GFVSEDEYLE-- 188

Query: 212 HSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYSVCVVEVK--------VSDSRRIG 263
                         + DI R   G Y+C+  N+V  +  V +VK        +S ++  G
Sbjct: 189 --------------ISDIKRDQSGEYECSALNDVA-APDVRKVKITVNYPPYISKAKNTG 233

Query: 264 VIIG 267
           V +G
Sbjct: 234 VSVG 237


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,005,653
Number of Sequences: 37866
Number of extensions: 911921
Number of successful extensions: 8727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 5106
Number of HSP's gapped (non-prelim): 2574
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.