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Search of human proteins with 61743980
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743980 stabilin 2 precursor [Homo sapiens]
(2551 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743980 stabilin 2 precursor [Homo sapiens] 5450 0.0
gi|61743978 stabilin 1 precursor [Homo sapiens] 2067 0.0
gi|24430141 fibrillin 1 precursor [Homo sapiens] 126 3e-28
gi|126091152 cubilin [Homo sapiens] 123 3e-27
gi|66346695 fibrillin 2 precursor [Homo sapiens] 120 1e-26
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 112 6e-24
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 112 6e-24
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 109 4e-23
gi|134244285 Notch homolog 3 [Homo sapiens] 108 5e-23
gi|26051243 tumor necrosis factor, alpha-induced protein 6 precu... 107 2e-22
gi|153946395 tenascin C precursor [Homo sapiens] 107 2e-22
gi|56237021 fibrillin 3 precursor [Homo sapiens] 105 7e-22
gi|24041035 notch 2 preproprotein [Homo sapiens] 104 1e-21
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 104 1e-21
gi|4557679 jagged 1 precursor [Homo sapiens] 103 2e-21
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 103 2e-21
gi|148833508 notch1 preproprotein [Homo sapiens] 102 6e-21
gi|55770876 notch4 preproprotein [Homo sapiens] 101 8e-21
gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens] 100 2e-20
gi|188528675 slit homolog 1 [Homo sapiens] 99 4e-20
gi|144953895 nidogen 2 precursor [Homo sapiens] 97 2e-19
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens] 97 2e-19
gi|115298674 nidogen 1 precursor [Homo sapiens] 97 2e-19
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho... 97 3e-19
gi|126012562 low density lipoprotein-related protein 1 [Homo sap... 96 6e-19
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens] 95 8e-19
gi|46249414 latent transforming growth factor beta binding prote... 95 1e-18
gi|46249412 latent transforming growth factor beta binding prote... 95 1e-18
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 95 1e-18
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 95 1e-18
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 5450 bits (14137), Expect = 0.0
Identities = 2551/2551 (100%), Positives = 2551/2551 (100%)
Query: 1 MMLQHLVIFCLGLVVQNFCSPAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTM 60
MMLQHLVIFCLGLVVQNFCSPAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTM
Sbjct: 1 MMLQHLVIFCLGLVVQNFCSPAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTM 60
Query: 61 ITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPC 120
ITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPC
Sbjct: 61 ITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPC 120
Query: 121 NGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGT 180
NGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGT
Sbjct: 121 NGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGT 180
Query: 181 CECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP 240
CECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP
Sbjct: 181 CECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP 240
Query: 241 CLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGP 300
CLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGP
Sbjct: 241 CLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGP 300
Query: 301 GQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLT 360
GQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLT
Sbjct: 301 GQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLT 360
Query: 361 CYGNIMERLRELNTEPRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNV 420
CYGNIMERLRELNTEPRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNV
Sbjct: 361 CYGNIMERLRELNTEPRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNV 420
Query: 421 NELLVDNKAAQYFVKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGG 480
NELLVDNKAAQYFVKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGG
Sbjct: 421 NELLVDNKAAQYFVKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGG 480
Query: 481 KKKVKIIQGDIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNL 540
KKKVKIIQGDIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNL
Sbjct: 481 KKKVKIIQGDIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNL 540
Query: 541 GHALDEDGVGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVA 600
GHALDEDGVGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVA
Sbjct: 541 GHALDEDGVGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVA 600
Query: 601 TLISTPHIRSMANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPI 660
TLISTPHIRSMANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPI
Sbjct: 601 TLISTPHIRSMANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPI 660
Query: 661 LPHRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCN 720
LPHRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCN
Sbjct: 661 LPHRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCN 720
Query: 721 ATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSD 780
ATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSD
Sbjct: 721 ATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSD 780
Query: 781 PNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH 840
PNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH
Sbjct: 781 PNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH 840
Query: 841 ATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG 900
ATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG
Sbjct: 841 ATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG 900
Query: 901 WTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQ 960
WTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQ
Sbjct: 901 WTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQ 960
Query: 961 TGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQ 1020
TGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQ
Sbjct: 961 TGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQ 1020
Query: 1021 PTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSS 1080
PTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSS
Sbjct: 1021 PTLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSS 1080
Query: 1081 DMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNL 1140
DMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNL
Sbjct: 1081 DMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNL 1140
Query: 1141 LMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLR 1200
LMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLR
Sbjct: 1141 LMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLR 1200
Query: 1201 YHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHG 1260
YHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHG
Sbjct: 1201 YHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHG 1260
Query: 1261 LGKVLEIQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLF 1320
LGKVLEIQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLF
Sbjct: 1261 LGKVLEIQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLF 1320
Query: 1321 IGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSG 1380
IGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSG
Sbjct: 1321 IGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSG 1380
Query: 1381 TACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTC 1440
TACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTC
Sbjct: 1381 TACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTC 1440
Query: 1441 HTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
HTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC
Sbjct: 1441 HTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
Query: 1501 KAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCL 1560
KAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCL
Sbjct: 1501 KAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCL 1560
Query: 1561 TKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPKTSQYFFQLQEHF 1620
TKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPKTSQYFFQLQEHF
Sbjct: 1561 TKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPKTSQYFFQLQEHF 1620
Query: 1621 VKDLVGPGPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNA 1680
VKDLVGPGPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNA
Sbjct: 1621 VKDLVGPGPFTVFAPLSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNA 1680
Query: 1681 TSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRI 1740
TSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRI
Sbjct: 1681 TSLQGEPIVISVSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRI 1740
Query: 1741 LQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFN 1800
LQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFN
Sbjct: 1741 LQNLTTLATNNGYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFN 1800
Query: 1801 QDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTC 1860
QDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTC
Sbjct: 1801 QDNKDKLKEYLKFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTC 1860
Query: 1861 RIVQRELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGV 1920
RIVQRELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGV
Sbjct: 1861 RIVQRELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGV 1920
Query: 1921 KQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQY 1980
KQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQY
Sbjct: 1921 KQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQY 1980
Query: 1981 SATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPS 2040
SATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPS
Sbjct: 1981 SATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPS 2040
Query: 2041 CDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCS 2100
CDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCS
Sbjct: 2041 CDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCS 2100
Query: 2101 QKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
QKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD
Sbjct: 2101 QKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
Query: 2161 GLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREAC 2220
GLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREAC
Sbjct: 2161 GLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREAC 2220
Query: 2221 ANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPN 2280
ANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPN
Sbjct: 2221 ANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPN 2280
Query: 2281 KSEMWDVFCYRMKDVNCTCKVGYVGDGFSCSGNLLQVLMSFPSLTNFLTEVLAYSNSSAR 2340
KSEMWDVFCYRMKDVNCTCKVGYVGDGFSCSGNLLQVLMSFPSLTNFLTEVLAYSNSSAR
Sbjct: 2281 KSEMWDVFCYRMKDVNCTCKVGYVGDGFSCSGNLLQVLMSFPSLTNFLTEVLAYSNSSAR 2340
Query: 2341 GRAFLEHLTDLSIRGTLFVPQNSGLGENETLSGRDIEHHLANVSMFFYNDLVNGTTLQTR 2400
GRAFLEHLTDLSIRGTLFVPQNSGLGENETLSGRDIEHHLANVSMFFYNDLVNGTTLQTR
Sbjct: 2341 GRAFLEHLTDLSIRGTLFVPQNSGLGENETLSGRDIEHHLANVSMFFYNDLVNGTTLQTR 2400
Query: 2401 LGSKLLITASQDPLQPTETRFVDGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGL 2460
LGSKLLITASQDPLQPTETRFVDGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGL
Sbjct: 2401 LGSKLLITASQDPLQPTETRFVDGRAILQWDIFASNGIIHVISRPLKAPPAPVTLTHTGL 2460
Query: 2461 GAGIFFAIILVTGAVALAAYSYFRINRRTIGFQHFESEEDINVAALGKQQPENISNPLYE 2520
GAGIFFAIILVTGAVALAAYSYFRINRRTIGFQHFESEEDINVAALGKQQPENISNPLYE
Sbjct: 2461 GAGIFFAIILVTGAVALAAYSYFRINRRTIGFQHFESEEDINVAALGKQQPENISNPLYE 2520
Query: 2521 STTSAPPEPSYDPFTDSEERQLEGNDPLRTL 2551
STTSAPPEPSYDPFTDSEERQLEGNDPLRTL
Sbjct: 2521 STTSAPPEPSYDPFTDSEERQLEGNDPLRTL 2551
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 2067 bits (5356), Expect = 0.0
Identities = 1048/2567 (40%), Positives = 1441/2567 (56%), Gaps = 104/2567 (4%)
Query: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI 90
CD K+ C SCA CP G+ + +DCRY ++ +S+ GCR
Sbjct: 32 CDVKTTFVTHVPCTSCAAIKKQTCPSGWLRELPDQI-TQDCRYEVQLGGSMVSMSGCRRK 90
Query: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
CRK +Q CCPG WG C ECPGGA +PCNG G+C +GM+ NGTC CQE F G+AC+ C
Sbjct: 91 CRKQVVQKACCPGYWGSRCHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSACQEC 150
Query: 151 ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC 210
D N FGP C SVC+CVHGVCN G GDG+C C++ YTGP CD+ +P C L CP+N++C
Sbjct: 151 QDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQC 210
Query: 211 SPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG 270
S C+CLP Y G C NPC C A C+ + C C E Y G
Sbjct: 211 SAEAPS-----CRCLPGYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
Query: 271 DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDN 330
DG VCLP DPC N G CP+ ST+C Y PGQ+ C C+ + C S
Sbjct: 266 DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTCRPGLVSINSNASAGCFAFC-SPF 324
Query: 331 PCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRGKWQGRLTSFISL 390
C R+A C A G+T C+C++ VGDG CYG+++ +++ R Q R+ +++
Sbjct: 325 SCDRSATCQVTADGKTSCVCRESEVGDGRACYGHLLHEVQKATQTGRVFLQLRVA--VAM 382
Query: 391 LDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAGQMNIE--YM 448
+D+ L+ GPFTVL+P+ +N L AQ + HIIAGQ +E
Sbjct: 383 MDQGCREILTTAGPFTVLVPSVSSFSSRTMNASL-----AQQLCRQHIIAGQHILEDTRT 437
Query: 449 NNTDMFYTLTGKSGEI-FNSDKDNQIKLKLHGGKKKVKIIQGDIIASNGLLHILDRAMDK 507
T ++TL G+ + FN K K ++ I + + IA+NG+ H++ +
Sbjct: 438 QQTRRWWTLAGQEITVTFNQFTKYSYKYK-DQPQQTFNIYKANNIAANGVFHVVTGLRWQ 496
Query: 508 LEPTFESNNEQTIMTMLQPR--YSKFRSLLEETNLGHALDEDGVGGPYTIFVPNNEALNN 565
+ ++TI +L +S+F ++LE L LD G P+T+F P+NEA+++
Sbjct: 497 APSGTPGDPKRTIGQILASTEAFSRFETILENCGLPSILDGPG---PFTVFAPSNEAVDS 553
Query: 566 MKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHIRSMANQLIQFNTTDNGQ 625
++DG L YL + G KL ELVRYHI QL V LIS I +MANQ++ N ++ G+
Sbjct: 554 LRDGRLIYLFTA-GLSKLQELVRYHIYNHGQLTVEKLISKGRILTMANQVLAVNISEEGR 612
Query: 626 ILAND--VAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRCDETKREMKLGTCVSCSLV 683
IL V ++ +++ A NG I+ L G+L+PP+I+PILP C E + ++ G+CV C +
Sbjct: 613 ILLGPEGVPLQRVDVMAANGVIHMLDGILLPPTILPILPKHCSEEQHKIVAGSCVDCQAL 672
Query: 684 YWSRCPANSEPTALFTHRCVY---SGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQC 740
S CP NS +F CVY LK GCA YCN T+ CCKGF+GPDC QC
Sbjct: 673 NTSTCPPNSVKLDIFPKECVYIHDPTGLNVLKKGCASYCNQTIMEQGCCKGFFGPDCTQC 732
Query: 741 PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCN 800
PGGFSNPC G G C+D + GNG C+C ++G C CS+PNK+G +C + C CVHG C+
Sbjct: 733 PGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIACHICSNPNKHGEQCQEDCGCVHGLCD 792
Query: 801 NRIDSDGACLTGTCRDGSAGRLCDKQTSACGP--YVQFCHIHATCEYSNGTASCICKAGY 858
NR S G C GTC G +GR C++ CGP Q CH+HA C G A C C G+
Sbjct: 793 NRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQEGVARCRCLDGF 852
Query: 859 EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPS 918
EGDG C+ +PC+ GGCS NAEC+ GTH C C +GW+G+GR C I+ C L
Sbjct: 853 EGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDM 912
Query: 919 AGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
GGCH +A C YVGPGQ+ C CK GF G+G C PI C G CH LA+C++ G
Sbjct: 913 RGGCHTDALCSYVGPGQSRCTCKLGFAGDGYQCSPIDPCRAGNGGCHGLATCRAVGGGQR 972
Query: 979 SCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQPTLSATSNLTVLVPSQQA 1038
C C G+ GDGF CYG+ EL + +IF +W+ +A + TL A +T LVPS+ A
Sbjct: 973 VCTCPPGFGGDGFSCYGDIFRELEANAHFSIFYQWLKSAGI--TLPADRRVTALVPSEAA 1030
Query: 1039 TEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSSDMLATSLQGNFLHLAKVD 1098
+ ++++FWL +P L++ H L G +L L ++ AT + +
Sbjct: 1031 VRQLSPEDRAFWLQPRTLPNLVRAHFLQGALFEEELARLGGQEV-ATLNPTTRWEIRNIS 1089
Query: 1099 GNITIEGASIVDGDNAATNGVIHIINKVLVPQRRLTGSLPNLLMRLEQMPDYSIFRGYII 1158
G + ++ AS+ D ATNGV+HI+++VL+P R LL +L+ +P +S+FR +
Sbjct: 1090 GRVWVQNASVDVADLLATNGVLHILSQVLLPPRGDVPGGQGLLQQLDLVPAFSLFRELLQ 1149
Query: 1159 QYNLANAIEAADAYTVFAPNNNAIENYIREKKVLSLEEDVLRYHVVLEEKLLKNDLHNGM 1218
+ L IEAA AYT+F P N ++E + L+ D +R+HVVL E L L G
Sbjct: 1150 HHGLVPQIEAATAYTIFVPTNRSLE---AQGNSSHLDADTVRHHVVLGEALSMETLRKGG 1206
Query: 1219 HRETMLGFSYFLSFFLHNDQLYVNEAPINYTNVATDKGVIHGLGKVLEIQKNRCDNNDTT 1278
HR ++LG ++++ F+ H+ Q VN P+ + + GL VL + +RC ++
Sbjct: 1207 HRNSLLGPAHWIVFYNHSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGSSRCLHSHAE 1266
Query: 1279 IIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCA 1338
+R +C C+ C G + ++ C+Y S F R GC C + + +CC
Sbjct: 1267 ALREKCVNCTRRFRCTQGFQLQDTPRKSCVYRSGFSFSR----GCSYTCAKKIQVPDCCP 1322
Query: 1339 GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQA 1398
GFFG C+PCPG VC G+G C D G+G C C EGF GTACE C G+YG +C
Sbjct: 1323 GFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVCELGRYGPNCTGV 1382
Query: 1399 CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKC 1458
C C HG C +G GDGSC C+VGW+G+ CD T C C +ANC+ +S G ++C C
Sbjct: 1383 CDCAHGLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCAC 1442
Query: 1459 AAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCL 1518
AAG+ GNG C+ ++ C +GGCS A+C + PG+R CTC+ GY GDG +C EIN CL
Sbjct: 1443 AAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKVAPGQRTCTCQDGYMGDGELCQEINSCL 1502
Query: 1519 ENHGGCDKNAECTQTGPNQAACNCLPAYTGDG-KVCTLINVCLTKNGGCSEFAICNHTGQ 1577
+HGGC +AEC TGP Q +C+C Y+GDG + C L++ C NGGCS +A C TG
Sbjct: 1503 IHHGGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNGGCSPYATCKSTGD 1562
Query: 1578 VERTCTCKPNY-IGDGFTCRGSIYQELPKNPKTSQYFFQLQEHFVKDLVGPGPFTVFAP- 1635
+RTCTC + +GDG TCR + EL ++ S + +L E+ K+L G GPFT+F P
Sbjct: 1563 GQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEY--KELKGDGPFTIFVPH 1620
Query: 1636 ----LSAAFDEEARVKDWDKYGLMPQVLRYHVVACHQLLLENLKLISNATSLQGEPIVIS 1691
+ + DE AR++ + V RYHVV C +L E+L AT+L G P+ S
Sbjct: 1621 ADLMSNLSQDELARIRAHRQL-----VFRYHVVGCRRLRSEDLLEQGYATALSGHPLRFS 1675
Query: 1692 VSQSTVYINNKAKIISSDIISTNGIVHIIDKLLSPKNLLITPKDNSGRILQNLTTLATNN 1751
+ ++Y+N+ A+++SSD + NGI+H ID++L P L D++ +N+T A
Sbjct: 1676 EREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWEPDDAPIPRRNVTAAAQGF 1735
Query: 1752 GYIKFSNLIQDSGLLSVITDPIHTPVTLFWPTDQALHALPAEQQDFLFNQDNKDKLKEYL 1811
GY FS L++ +GLL ++ + H P T+ WPTD A ALP ++Q +L+++D++DKL L
Sbjct: 1736 GYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPDRQAWLYHEDHRDKLAAIL 1795
Query: 1812 KFHVIRDAKVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDL 1871
+ H+IR+ + LA DLP +T+ G+ +S C R G+L + RIVQR L F+
Sbjct: 1796 RGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTR-AGELMVGEDDARIVQRHLPFEG 1854
Query: 1872 GVAYGIDCLLIDPTLGGRCDTFTTFDAS-GECGSCVNTPSCPRWSKPKGVKQKC------ 1924
G+AYGID LL P LG RCD F T C C P CP S+ +G + C
Sbjct: 1855 GLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPEGSQEQGSPEACWRFYPK 1914
Query: 1925 LYNLPFKRNL-------------------EGCRERCSLVIQIPRCCKGYFGRDCQACPGG 1965
+ P +L GC C P CC G++G +CQACPGG
Sbjct: 1915 FWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKPSCCPGHYGSECQACPGG 1974
Query: 1966 PDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGIT 2025
P +PC++RGVC+D S +G+C C +GF GTACE+C PG FGP C C C+ HG+CD+G+
Sbjct: 1975 PSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPHCQACRCTVHGRCDEGLG 2034
Query: 2026 GSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF 2085
GSG C C+ GWTGP C+ Q L VCTPPC+ A C+ N+CEC+L YEGDG CTV D
Sbjct: 2035 GSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADL 2094
Query: 2086 CKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTG 2145
C+ +GGC++ A CSQ GT V+C+C Y+GDG SC +PC DG GGC EHA C TG
Sbjct: 2095 CQDGHGGCSEHANCSQVGTMVTCTCLPDYEGDGWSCRARNPCTDGHRGGCSEHANCLSTG 2154
Query: 2146 PGKHKCECKSHYVGDGLNC-EPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRS 2204
+CEC + YVGDGL C E + P+DRCL CH+DA C DLHFQ+ GVFHL++
Sbjct: 2155 LNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPPCHSDAMCTDLHFQEKRAGVFHLQA 2214
Query: 2205 PLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQN 2264
G Y L F +A AC + A +A++ QLS AQ+ +HLC GWL G A+P F +
Sbjct: 2215 TSGPYGLNFSEAEAACEAQGAVLASFPQLSAAQQLGFHLCLMGWLANGSTAHPVVFPVAD 2274
Query: 2265 CGSGVVGIVDYGPRPNKSEMWDVFCYRMKDVNCTCKVGYVGDGFS-CSGNLLQVLMSFPS 2323
CG+G VGIV G R N SE WD +C+R++DV C C+ G+VGDG S C+G LL VL + +
Sbjct: 2275 CGNGRVGIVSLGARKNLSERWDAYCFRVQDVACRCRNGFVGDGISTCNGKLLDVLAATAN 2334
Query: 2324 LTNFLTEVLAYSNSSARGRAFLEHLTDLSIRGTLFVPQNSGLGENETLSGRDIEHHLANV 2383
+ F +L Y+N++ RG FL+ L D TLFVP N G +N TLSG D+E H +N
Sbjct: 2335 FSTFYGMLLGYANATQRGLDFLDFLDDELTYKTLFVPVNEGFVDNMTLSGPDLELHASNA 2394
Query: 2384 SMFFYNDLVNGTTLQTRLGSKLLIT---ASQDPLQPTETRFVDGRAILQWDIFASNGIIH 2440
++ N G L G L+I+ P V I+ WDI A NGIIH
Sbjct: 2395 TLLSAN-ASQGKLLPAHSGLSLIISDAGPDNSSWAPVAPGTVVVSRIIVWDIMAFNGIIH 2453
Query: 2441 VISRPLKAPPAPVTL-----THTGLGAGIFFAIILVTGAVALAAYSYFRINRRTIGFQHF 2495
++ PL APP P + G G A + G VA A Y R GF F
Sbjct: 2454 ALASPLLAPPQPQAVLAPEAPPVAAGVGAVLAAGALLGLVAGALYLRARGKPMGFGFSAF 2513
Query: 2496 ESEEDINVAALGKQQPEN-----ISNPLYESTTSAPPEPSYDPFTDS 2537
++E+D + Q+ N + NP++ S T +PF DS
Sbjct: 2514 QAEDDADDDFSPWQEGTNPTLVSVPNPVFGSDTFC------EPFDDS 2554
Score = 801 bits (2070), Expect = 0.0
Identities = 518/1627 (31%), Positives = 775/1627 (47%), Gaps = 164/1627 (10%)
Query: 29 RRCDRKSLLTIRTECRSC-ALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGC 87
+ C + + C C ALN CP + + ++C Y + ++ GC
Sbjct: 652 KHCSEEQHKIVAGSCVDCQALNTST-CPPNSVKL---DIFPKECVYIHDPTGLNVLKKGC 707
Query: 88 RHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC 147
C + ++ CC G +GPDC +CPGG +PC G+G+C++G++GNG C C + G AC
Sbjct: 708 ASYCNQTIMEQGCCKGFFGPDCTQCPGGFSNPCYGKGNCSDGIQGNGACLCFPDYKGIAC 767
Query: 148 ETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCE---CYSAYTGPKCDKPIPECA---- 200
C++ N G C C CVHG+C++ G C+ C ++G C++ + +C
Sbjct: 768 HICSNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGL 827
Query: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCL---RKICHPHAHCTYLGP 257
A C ++RC E C+CL + GDG C P NPC R C +A C
Sbjct: 828 AQHCHLHARC---VSQEGVARCRCLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSL 884
Query: 258 NRHSCTCQEGYRGDGQVCLPVDPCQINF-GNCPTKSTVCKYDGPGQSHCECKEHYQNFVP 316
H CTC +G+ GDG+VC+ +D C+++ G C T + +C Y GPGQS C CK +
Sbjct: 885 GTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA-LCSYVGPGQSRCTCKLGFAG--D 941
Query: 317 GVGCSMTDICKSDNP-CHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTE 375
G CS D C++ N CH A C V G+ C C G+ GDG +CYG+I L E N
Sbjct: 942 GYQCSPIDPCRAGNGGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDIFREL-EANAH 1000
Query: 376 PRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNE--LLVDNKAAQYF 433
+Q ++ I+L P + T L+P++ ++ + + + +
Sbjct: 1001 FSIFYQWLKSAGITL-------PADRR--VTALVPSEAAVRQLSPEDRAFWLQPRTLPNL 1051
Query: 434 VKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDKDNQIKLKLHGGK---KKVKIIQGD 490
V+ H + G + E + L G+ E+ + + +++ G+ + + D
Sbjct: 1052 VRAHFLQGALFEEELAR------LGGQ--EVATLNPTTRWEIRNISGRVWVQNASVDVAD 1103
Query: 491 IIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQ--PRYSKFRSLLEETNLGHALDEDG 548
++A+NG+LHIL + + L P + Q ++ L P +S FR LL+ L ++
Sbjct: 1104 LLATNGVLHILSQVL--LPPRGDVPGGQGLLQQLDLVPAFSLFRELLQHHGLVPQIE--- 1158
Query: 549 VGGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRYHIVPFTQLEVATLISTPHI 608
YTIFVP N +L G +L + + VR+H+V L + TL H
Sbjct: 1159 AATAYTIFVPTNRSLE--AQGNSSHLDA--------DTVRHHVVLGEALSMETLRKGGHR 1208
Query: 609 RSM---ANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRC 665
S+ A+ ++ +N +GQ N V +E + A + L+GVL S RC
Sbjct: 1209 NSLLGPAHWIVFYN--HSGQPEVNHVPLEGPMLEAPGRSLIGLSGVLTVGS------SRC 1260
Query: 666 DETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKI 725
+ E CV+C+ + RC + CVY F S GC+ C +++
Sbjct: 1261 LHSHAEALREKCVNCTRRF--RCTQGFQLQDTPRKSCVYRSGF-SFSRGCSYTCAKKIQV 1317
Query: 726 PKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
P CC GF+G C CPGG CSG+GQC D G+G C C EGF G+ C+ C + +YG
Sbjct: 1318 PDCCPGFFGTLCEPCPGGLGGVCSGHGQCQDRFLGSGECHCHEGFHGTACEVC-ELGRYG 1376
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQ-TSACGPYVQFCHIHATC- 843
P C C C HG C + DG+C+ C G G CD++ TS P + C +A C
Sbjct: 1377 PNCTGVCDCAHGLCQEGLQGDGSCV---CNVGWQGLRCDQKITSPQCP--RKCDPNANCV 1431
Query: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903
+ S G ++C C AGY G+G CSE+DPC GGCS +A C K G TC CQ G+ G
Sbjct: 1432 QDSAGASTCACAAGYSGNGIFCSEVDPCAH-GHGGCSPHANCTKVAPGQRTCTCQDGYMG 1490
Query: 904 NGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGI-DCEPITSCLEQTG 962
+G C EIN+CL+ GGCH +A C+ GP Q C C++G+ G+GI CE + C + G
Sbjct: 1491 DGELCQEINSCLIHH-GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTCELLDPCSKNNG 1549
Query: 963 KCHPLASCQSTSSGVWSCVCQEGYE-GDGFLCYGNAAVELSFLSEAAIFNRWINNASLQP 1021
C P A+C+ST G +C C + GDG C +EL A+ F+ +
Sbjct: 1550 GCSPYATCKSTGDGQRTCTCDTAHTVGDGLTCRARVGLELLRDKHASFFSLRLLEYK--- 1606
Query: 1022 TLSATSNLTVLVPSQQATEDMDQDEKSFWLSQSNIPALIKYHMLLGTYRVADLQTLSSSD 1081
L T+ VP ++ QDE + + + L+ Y V + L S D
Sbjct: 1607 ELKGDGPFTIFVPHADLMSNLSQDE---------LARIRAHRQLVFRYHVVGCRRLRSED 1657
Query: 1082 ML----ATSLQGNFLHLAKVDGNITIEG-ASIVDGDNAATNGVIHIINKVLVPQRRL--- 1133
+L AT+L G+ L ++ +G+I + A +V D+ A NG++H I++VL+P L
Sbjct: 1658 LLEQGYATALSGHPLRFSEREGSIYLNDFARVVSSDHEAVNGILHFIDRVLLPPEALHWE 1717
Query: 1134 --TGSLPNL-LMRLEQMPDYSIFRGYIIQYNLANAIEAAD--AYTVFAPNNNAIENYIRE 1188
+P + Q Y IF G + L + A +T+ P + A +
Sbjct: 1718 PDDAPIPRRNVTAAAQGFGYKIFSGLLKVAGLLPLLREASHRPFTMLWPTDAAFRALPPD 1777
Query: 1189 KKVLSLEED-------VLRYHVVLEEKLLKNDLHNGMHRETMLGFSYFLSFF-LHNDQLY 1240
++ ED +LR H++ + L +DL N TM G S +L
Sbjct: 1778 RQAWLYHEDHRDKLAAILRGHMIRNVEALASDLPNLGPLRTMHGTPISFSCSRTRAGELM 1837
Query: 1241 VNE--APINYTNVATDKGVIHGLGKVLEIQK--NRCDNNDTTIIR-GRCRTCSSELTCPF 1295
V E A I ++ + G+ +G+ ++LE RCD+ +T +R C C E CP
Sbjct: 1838 VGEDDARIVQRHLPFEGGLAYGIDQLLEPPGLGARCDHFETRPLRLNTCSICGLEPPCPE 1897
Query: 1296 GTKSLGNEKRRCIYTSYF--------MGRRTLFI-------------GCQPKCVRTVITR 1334
G++ G+ + + F +G R++++ GC CV T
Sbjct: 1898 GSQEQGSPEACWRFYPKFWTSPPLHSLGLRSVWVHPSLWGRPQGLGRGCHRNCVTTTWKP 1957
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
CC G +G +CQ CPG + C G+C+DG++G+G C C GF+GTACE C G +G H
Sbjct: 1958 SCCPGHYGSECQACPGGPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTACELCAPGAFGPH 2017
Query: 1395 CDQACSC-VHGRCNQGPLGDGSCDCDVGWRGVHCD-NATTEDNCNGTCHTSANCLTNSDG 1452
C QAC C VHGRC++G G GSC CD GW G C+ + C C A C +
Sbjct: 2018 C-QACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVCRAGN-- 2074
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRV-CTCKAGYTGDGIVC 1511
SC+C+ G++G+G +CT + C+ +GGCS A+C + G V CTC Y GDG C
Sbjct: 2075 --SCECSLGYEGDGRVCTVADLCQDGHGGCSEHANCSQV--GTMVTCTCLPDYEGDGWSC 2130
Query: 1512 LEINPCLENH-GGCDKNAECTQTGPNQAACNCLPAYTGDGKVC-----TLINVCLTKNGG 1565
NPC + H GGC ++A C TG N C C Y GDG C ++ CL +
Sbjct: 2131 RARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEPPVDRCLGQPPP 2190
Query: 1566 CSEFAIC 1572
C A+C
Sbjct: 2191 CHSDAMC 2197
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 126 bits (316), Expect = 3e-28
Identities = 102/344 (29%), Positives = 150/344 (43%), Gaps = 38/344 (11%)
Query: 663 HRCDETKREMKLGTCVSCSLVYWSRCPA--NSEPTALFTHRCVYSGRFGSLKSGCARYCN 720
+ C+ + G CV+ Y C +S P LF CV + GC +C
Sbjct: 1157 NECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLF---CVDIDECSIMNGGCETFCT 1213
Query: 721 ATVKIPKC-CKGFYG--PDCNQCPG-----GFSNPCSGNGQCADSLGGNGTCICEEGFQG 772
+ +C C+ + PD C N C G GQC + + G C+C +GF
Sbjct: 1214 NSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDG-GQCTN-IPGEYRCLCYDGFMA 1271
Query: 773 SQ-CQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACG 831
S+ + C D N+ N +C+ GTC N S C G G+ + C
Sbjct: 1272 SEDMKTCVDVNECDLNPN---ICLSGTCENTKGSF-ICHCDMGYSGKKGKTGCTDINECE 1327
Query: 832 PYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTG 891
C HA C + G+ C C G+ GDG C+++D C+ T CS++A+C K G
Sbjct: 1328 IGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHM-CSQHADC-KNTMG 1385
Query: 892 THTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGI 949
++ C+C++G+TG+G C++++ C + C N CL PG CEC GF +G
Sbjct: 1386 SYRCLCKEGYTGDGFTCTDLDECS-ENLNLC-GNGQCLNA-PGGYRCECDMGFVPSADGK 1442
Query: 950 DCEPITSCLEQT----GKCHPLASCQSTSSGVWSCVCQEGYEGD 989
CE I C G CH L G++ C C+ GYE D
Sbjct: 1443 ACEDIDECSLPNICVFGTCHNLP-------GLFRCECEIGYELD 1479
Score = 110 bits (275), Expect = 2e-23
Identities = 89/283 (31%), Positives = 125/283 (44%), Gaps = 29/283 (10%)
Query: 1322 GCQPKCVRTVITREC-CAGFFG--PQCQPCPG-----NAQNVCFGNGICLDGVNGTGVCE 1373
GC+ C + + EC C F P + C + N+C G G C + + G C
Sbjct: 1207 GCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDG-GQCTN-IPGEYRCL 1264
Query: 1374 CGEGFSGTA-CETCTEGKYGIHCDQACS-CVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431
C +GF + +TC + CD + C+ G C + G C CD+G+ G
Sbjct: 1265 CYDGFMASEDMKTCVDVN---ECDLNPNICLSGTC-ENTKGSFICHCDMGYSGKKGKTGC 1320
Query: 1432 TEDN-CN---GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKAD 1487
T+ N C C A C TN+ G+ C C+ G+ G+G CT ++ C CS AD
Sbjct: 1321 TDINECEIGAHNCGKHAVC-TNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHAD 1379
Query: 1488 CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY- 1546
CK T R C CK GYTGDG C +++ C EN C N +C P C C +
Sbjct: 1380 CKNTMGSYR-CLCKEGYTGDGFTCTDLDECSENLNLCG-NGQCL-NAPGGYRCECDMGFV 1436
Query: 1547 -TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
+ DGK C I+ C N F C++ + R C C+ Y
Sbjct: 1437 PSADGKACEDIDECSLPN--ICVFGTCHNLPGLFR-CECEIGY 1476
Score = 103 bits (257), Expect = 2e-21
Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 22/247 (8%)
Query: 1359 NGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQ---GPLGDGS 1415
NG C++ + G C C G+ T + + + D+ CS ++G C G
Sbjct: 1168 NGRCVNLI-GKYQCACNPGYHSTP-----DRLFCVDIDE-CSIMNGGCETFCTNSEGSYE 1220
Query: 1416 CDCDVGWRGVHCDNATTE-DNC--NGTCHTSANCLTNSDGTASCKCAAGFQGNGTI--CT 1470
C C G+ + + T+ D C N C TN G C C GF + + C
Sbjct: 1221 CSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC-TNIPGEYRCLCYDGFMASEDMKTCV 1279
Query: 1471 AINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDG--IVCLEINPCLENHGGCDKNA 1528
+N C+++ C + C+ T G +C C GY+G C +IN C C K+A
Sbjct: 1280 DVNECDLNPNICLS-GTCENTK-GSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHA 1337
Query: 1529 ECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
CT T C+C P + GDG CT ++ C CS+ A C +T R C CK Y
Sbjct: 1338 VCTNTA-GSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYR-CLCKEGY 1395
Query: 1589 IGDGFTC 1595
GDGFTC
Sbjct: 1396 TGDGFTC 1402
Score = 97.1 bits (240), Expect = 2e-19
Identities = 88/304 (28%), Positives = 117/304 (38%), Gaps = 37/304 (12%)
Query: 70 DCRYTFEVRTYSLSLPGCRHICRKDY--LQPRCCPG-------RWGPDCIECPGGAGSPC 120
D + ++ S+ GC C + C PG R D EC C
Sbjct: 1191 DRLFCVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNI-C 1249
Query: 121 NGRGSCAEGMEGNGTCSCQEGFGGTA-CETCADDNLFGPSCSSVCN-CVHGVCNSGLDGD 178
+G G C + G C C +GF + +TC D N C N C+ G C + G
Sbjct: 1250 DG-GQCTN-IPGEYRCLCYDGFMASEDMKTCVDVN----ECDLNPNICLSGTCEN-TKGS 1302
Query: 179 GTCECYSAYTGPKCDK---PIPEC--AALLCPENSRCSPSTEDENKLECKCLPNYRGDGK 233
C C Y+G K I EC A C +++ C T +C C P + GDG
Sbjct: 1303 FICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVC---TNTAGSFKCSCSPGWIGDGI 1359
Query: 234 YCDPINPCLR--KICHPHAHC-TYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPT 290
C ++ C +C HA C +G R C C+EGY GDG C +D C N C
Sbjct: 1360 KCTDLDECSNGTHMCSQHADCKNTMGSYR--CLCKEGYTGDGFTCTDLDECSENLNLCGN 1417
Query: 291 KSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECIC 350
+ + PG CEC + G C D C N C C + PG C C
Sbjct: 1418 GQCL---NAPGGYRCECDMGFVPSADGKACEDIDECSLPNIC-VFGTCHNL-PGLFRCEC 1472
Query: 351 QKGY 354
+ GY
Sbjct: 1473 EIGY 1476
Score = 96.3 bits (238), Expect = 3e-19
Identities = 74/264 (28%), Positives = 103/264 (39%), Gaps = 44/264 (16%)
Query: 1950 CCKGYFGRDCQACPGGPDAP----CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C +C PG P C + C D + +C T G +C+ G
Sbjct: 1212 CTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQC-TNIPGEYRCLCYDGFM 1270
Query: 2006 GPDCLPCGCSDHGQCD-----------DGITGSGQCLCETGWTGPSCDTQAVLPAVC--- 2051
+ + C D +CD + GS C C+ G++G T C
Sbjct: 1271 ASEDMKT-CVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
Query: 2052 TPPCSAHATCKENN---TCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC 2108
C HA C C C+ + GDGI CT +D C C++ A C C
Sbjct: 1330 AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRC 1389
Query: 2109 SCQKGYKGDGHSCTEIDPCADGL----NGGCHEHATCKMTGPGKHKCECKSHYV--GDGL 2162
C++GY GDG +CT++D C++ L NG C + PG ++CEC +V DG
Sbjct: 1390 LCKEGYTGDGFTCTDLDECSENLNLCGNGQC-------LNAPGGYRCECDMGFVPSADGK 1442
Query: 2163 NCEPEQLPIDRCLQDN----GQCH 2182
CE ID C N G CH
Sbjct: 1443 ACE----DIDECSLPNICVFGTCH 1462
Score = 94.0 bits (232), Expect = 2e-18
Identities = 76/268 (28%), Positives = 112/268 (41%), Gaps = 30/268 (11%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ-FCSDPNKYGPRCNKKCLC 794
D N+C S NG+C + +G C C G+ + + FC D ++ C
Sbjct: 1155 DINECE--LSAHLCPNGRCVNLIG-KYQCACNPGYHSTPDRLFCVDIDE--------CSI 1203
Query: 795 VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA-----CGPYVQFCHIHATCEYSNGT 849
++G C + +C+ G A L Q S C C C G
Sbjct: 1204 MNGGCETFCTNSEGSYECSCQPGFA--LMPDQRSCTDIDECEDNPNICD-GGQCTNIPGE 1260
Query: 850 ASCICKAGYEG--DGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNG-- 905
C+C G+ D C +++ C L P C + C T G+ C C G++G
Sbjct: 1261 YRCLCYDGFMASEDMKTCVDVNECD-LNPNICL-SGTCENT-KGSFICHCDMGYSGKKGK 1317
Query: 906 RDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCH 965
C++IN C + A C +A C G +C C G+ G+GI C + C T C
Sbjct: 1318 TGCTDINECEI-GAHNCGKHAVCTNTA-GSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS 1375
Query: 966 PLASCQSTSSGVWSCVCQEGYEGDGFLC 993
A C++T G + C+C+EGY GDGF C
Sbjct: 1376 QHADCKNTM-GSYRCLCKEGYTGDGFTC 1402
Score = 91.7 bits (226), Expect = 9e-18
Identities = 76/264 (28%), Positives = 114/264 (43%), Gaps = 40/264 (15%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCV 795
D ++C G C N +C ++ G+ C C+ G++ + C+D N+ N +C
Sbjct: 1808 DIDECQNG--PVCQRNAECINT-AGSYRCDCKPGYRFTSTGQCNDRNECQEIPN---ICS 1861
Query: 796 HGTCNNRIDSDGA----CLTGTCRDGSAGRLCDK---QTSACGPYVQFCHIHATCEYSNG 848
HG C ID+ G+ C TG + D + ACG + TC + G
Sbjct: 1862 HGQC---IDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACG--------NGTCRNTIG 1910
Query: 849 TASCICKAGYE-GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGNG 905
+ +C C G+ C ++D C G RN +CI T G+ C C +G+ +G
Sbjct: 1911 SFNCRCNHGFILSHNNDCIDVDECASGN-GNLCRNGQCINT-VGSFQCQCNEGYEVAPDG 1968
Query: 906 RDCSEINNCLLPS---AGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTG 962
R C +IN CLL A G N G C C G+ CE I C+E+
Sbjct: 1969 RTCVDINECLLEPRKCAPGTCQNLD------GSYRCICPPGYSLQNEKCEDIDECVEEPE 2022
Query: 963 KCHPLASCQSTSSGVWSCVCQEGY 986
C L +C +T G + C+C EG+
Sbjct: 2023 IC-ALGTCSNT-EGSFKCLCPEGF 2044
Score = 90.5 bits (223), Expect = 2e-17
Identities = 74/258 (28%), Positives = 106/258 (41%), Gaps = 35/258 (13%)
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT----ACETCTEGKYGIHCDQAC 1399
+C+ PG VC NG+C++ V G+ CEC GF CE E + G C +
Sbjct: 1769 ECREIPG----VC-ENGVCINMV-GSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNA 1822
Query: 1400 SCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSAN--CLTNSDGTASCK 1457
C++ G CDC G+R + C + ++ C+ ++ G+ C
Sbjct: 1823 ECIN------TAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCI-DTVGSFYCL 1875
Query: 1458 CAAGFQGNG--TICTAINACE---ISNGGCSAKADCKRTTPGRRVCTCKAGYT-GDGIVC 1511
C GF+ N T+C IN CE NG C R T G C C G+ C
Sbjct: 1876 CHTGFKTNDDQTMCLDINECERDACGNGTC-------RNTIGSFNCRCNHGFILSHNNDC 1928
Query: 1512 LEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1570
++++ C +G +N +C T G Q CN DG+ C IN CL + C+
Sbjct: 1929 IDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGT 1988
Query: 1571 ICNHTGQVERTCTCKPNY 1588
N G C C P Y
Sbjct: 1989 CQNLDGSYR--CICPPGY 2004
Score = 83.2 bits (204), Expect = 3e-15
Identities = 68/262 (25%), Positives = 110/262 (41%), Gaps = 37/262 (14%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGF-QGSQCQFCSDPNKY--GPRCNKKC 792
+C + PG NG C + +G + C C GF + C D ++ GP C +
Sbjct: 1769 ECREIPG-----VCENGVCINMVG-SFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNA 1822
Query: 793 LCVHGTCNNRIDSDGA---CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGT 849
C++ + R D TG C D + C + + C H C + G+
Sbjct: 1823 ECINTAGSYRCDCKPGYRFTSTGQCNDRNE---CQEIPNICS--------HGQCIDTVGS 1871
Query: 850 ASCICKAGYE--GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT-GNGR 906
C+C G++ D T+C +++ C G N C T G+ C C G+ +
Sbjct: 1872 FYCLCHTGFKTNDDQTMCLDINECERDACG----NGTCRNT-IGSFNCRCNHGFILSHNN 1926
Query: 907 DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR--GNGIDCEPITSCLEQTGKC 964
DC +++ C + C N C+ G +C+C +G+ +G C I CL + KC
Sbjct: 1927 DCIDVDECASGNGNLCR-NGQCINT-VGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKC 1984
Query: 965 HPLASCQSTSSGVWSCVCQEGY 986
P +CQ+ G + C+C GY
Sbjct: 1985 AP-GTCQNL-DGSYRCICPPGY 2004
Score = 79.0 bits (193), Expect = 6e-14
Identities = 65/233 (27%), Positives = 92/233 (39%), Gaps = 25/233 (10%)
Query: 1958 DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDH 2017
D C GP C C++ + + C C G+ T+ C R +P CS H
Sbjct: 1808 DIDECQNGP--VCQRNAECINT-AGSYRCDCKPGYRFTSTGQC-NDRNECQEIPNICS-H 1862
Query: 2018 GQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE---NNTCECN---- 2070
GQC D + GS CLC TG+ T + C + TC+ + C CN
Sbjct: 1863 GQCIDTV-GSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFI 1921
Query: 2071 LDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCA 2128
L + D C VD C NG + +C C C +GY+ DG +C +I+ C
Sbjct: 1922 LSHNND---CIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECL 1978
Query: 2129 DGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
L TC+ G ++C C Y CE ID C+++ C
Sbjct: 1979 --LEPRKCAPGTCQNL-DGSYRCICPPGYSLQNEKCE----DIDECVEEPEIC 2024
Score = 74.7 bits (182), Expect = 1e-12
Identities = 73/272 (26%), Positives = 104/272 (38%), Gaps = 49/272 (18%)
Query: 751 NGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCL---CVHGTCNNRIDSDG 807
NG+C ++ G TC C +GF S Q N+ G C + L C G+ N +
Sbjct: 2304 NGRCLNTRGSY-TCECNDGFTASPNQDECLDNREG-YCFTEVLQNMCQIGSSNRNPVTKS 2361
Query: 808 ACLTGTCRDGSAG-----RLCDKQTSAC--------------GPYVQFCHI------HAT 842
C C DG G +C Q + G + C + +
Sbjct: 2362 EC----CCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE 2417
Query: 843 CEYSNGTASCICKAGYEGD--GTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG 900
C G+ CICK GY D GT C +++ C P C N C K G++ C C +G
Sbjct: 2418 CVNDRGSYHCICKTGYTPDITGTSCVDLNEC-NQAPKPC--NFIC-KNTEGSYQCSCPKG 2473
Query: 901 W--TGNGRDCSEINNCLLPSAGGCHDNASCLYVGP-GQNECECKKGFRGNGIDCEPITSC 957
+ +GR C +++ C N L V G C+C GF + C C
Sbjct: 2474 YILQEDGRSCKDLDECATK-----QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNEC 2528
Query: 958 LEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
C CQ+T G ++C CQ G+ D
Sbjct: 2529 TSDINLCGSKGICQNT-PGSFTCECQRGFSLD 2559
Score = 73.6 bits (179), Expect = 2e-12
Identities = 99/361 (27%), Positives = 132/361 (36%), Gaps = 76/361 (21%)
Query: 1267 IQKNRCDNNDTTIIRGRC---RTCSS-----ELTCPFGTKSLGNEKRRC--IYTSYFMGR 1316
+Q +C++ D + TCS+ + CP G SL + RRC + SY +
Sbjct: 2006 LQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGF-SLSSSGRRCQDLRMSYCYAK 2064
Query: 1317 RTLFIG--CQPKCVRTVITRECCAGF----FGPQCQPCPGNA----QNVC-FGNGICLDG 1365
F G C R +ECC +G C+ CP + +C +G+GI +
Sbjct: 2065 ---FEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIV-- 2119
Query: 1366 VNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGW--R 1423
G S + C E C HG+C G C+C G+
Sbjct: 2120 ---------GPDDSAVDMDECKEPDV---------CKHGQCINTD-GSYRCECPFGYILA 2160
Query: 1424 GVHC---DNATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGFQ-GNGTICTAINACEIS 1478
G C D + + C NGTC N G C C GF+ G C IN C +
Sbjct: 2161 GNECVDTDECSVGNPCGNGTCK-------NVIGGFECTCEEGFEPGPMMTCEDINECAQN 2213
Query: 1479 NGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLENHGGC-DKNAECTQTGP 1535
C+ + T G C C GY D +C + + C E C +K EC
Sbjct: 2214 PLLCAFRCV---NTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNL-I 2269
Query: 1536 NQAACNCLPAYTG--DGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF 1593
C C P Y DG+ C N C TK G C N G TC C DGF
Sbjct: 2270 GTYMCICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSY--TCEC-----NDGF 2322
Query: 1594 T 1594
T
Sbjct: 2323 T 2323
Score = 73.6 bits (179), Expect = 2e-12
Identities = 92/361 (25%), Positives = 124/361 (34%), Gaps = 77/361 (21%)
Query: 1267 IQKNRCDNNDTTIIRGRCRTCSSELTC---------PFGTKSLGNEKRRCIYTSYFMGRR 1317
+ +N C GRC TC P + L N + C +T
Sbjct: 2290 VDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYC-FTEVLQNM- 2347
Query: 1318 TLFIGCQ-PKCVRTVITRE--CCAGF--FGPQCQPCPGNAQNVCFGNGICLDG----VNG 1368
CQ R +T+ CC G +GP C+ CP Q +C G NG
Sbjct: 2348 -----CQIGSSNRNPVTKSECCCDGGRGWGPHCEICP--FQGTVAFKKLCPHGRGFMTNG 2400
Query: 1369 TGVCECGEGFSGTACETCTEGKYGIHCD---------QACSCVH-GRCNQGPL------- 1411
+ EC C + HC SCV CNQ P
Sbjct: 2401 ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFICK 2460
Query: 1412 ---GDGSCDCDVGW----RGVHCDN----ATTEDNCNGTCHTSANCLTNSDGTASCKCAA 1460
G C C G+ G C + AT + NC C N+ G +CKC
Sbjct: 2461 NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLC-------VNTIGGFTCKCPP 2513
Query: 1461 GFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCL 1518
GF + T C N C C +K C + TPG C C+ G++ D G C +++ C
Sbjct: 2514 GFTQHHTSCIDNNECTSDINLCGSKGIC-QNTPGSFTCECQRGFSLDQTGSSCEDVDECE 2572
Query: 1519 ENHGGCDKNAECTQTGPNQAACNCLPAYTG--DGKVCTLINVCLTKN--GGCSEFAICNH 1574
NH C + G C+C Y C N CL+ + GG S C++
Sbjct: 2573 GNH-RCQHGCQNIIGG---YRCSCPQGYLQHYQWNQCVDENECLSAHICGGAS----CHN 2624
Query: 1575 T 1575
T
Sbjct: 2625 T 2625
Score = 72.4 bits (176), Expect = 5e-12
Identities = 90/373 (24%), Positives = 151/373 (40%), Gaps = 84/373 (22%)
Query: 727 KCCKGFYGP------DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS----QCQ 776
+C KGF D ++C NPC+G G+C ++ G TC C G+Q + +C+
Sbjct: 475 ECNKGFQLDLRGECIDVDECE---KNPCAG-GECINNQGSY-TCQCRAGYQSTLTRTECR 529
Query: 777 FCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGA----CLTG--TCRDGSAGRLCDKQTSAC 830
+ + G CN +G C I++DG+ C G RDG + C+
Sbjct: 530 DIDECLQNGRICN------NGRC---INTDGSFHCVCNAGFHVTRDG---KNCEDMDECS 577
Query: 831 GPYVQFCHIHATCEYSNGTASCICKAGYE--GDGTLCSEMDPCTGLTPGGCSRNAECIKT 888
++ ++ C +G+ CICK G++ DG C +++ C TPG C N C+ T
Sbjct: 578 ---IRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECE--TPGICM-NGRCVNT 631
Query: 889 GTGTHTCVCQQGWTG--NGRDCSEINNCLLPSAGGCHDNASC---LYVGPGQNECECKKG 943
G++ C C G +GR C ++ + + G + C L+ ++EC C
Sbjct: 632 D-GSYRCECFPGLAVGLDGRVC--VDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCAST 688
Query: 944 FRGNGIDCEP------------------ITSCLEQTGKCH------PLASCQSTSSGVWS 979
G C+P +TS +C P C++ G +
Sbjct: 689 EYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLR-GTYK 747
Query: 980 CVCQEGYEGDGFLCYGNAAVELSFLSEAAIFNRWINNASLQPT----LSATSNLTVLVPS 1035
C+C GYE D G V+ ++E + + +N + T + + P
Sbjct: 748 CICNSGYEVDS---TGKNCVD---INECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPD 801
Query: 1036 QQATEDMDQDEKS 1048
+ ED+D+ E S
Sbjct: 802 LKTCEDIDECESS 814
Score = 71.2 bits (173), Expect = 1e-11
Identities = 70/258 (27%), Positives = 109/258 (42%), Gaps = 25/258 (9%)
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-CTEGKYGIHCDQACSCV 1402
+CQ P N+C +G C+D V G+ C C GF +T C + I+ + +C
Sbjct: 1852 ECQEIP----NIC-SHGQCIDTV-GSFYCLCHTGFKTNDDQTMCLD----INECERDACG 1901
Query: 1403 HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC---NGTCHTSANCLTNSDGTASCKCA 1459
+G C + +G +C C+ G+ H ++ D C NG + C+ N+ G+ C+C
Sbjct: 1902 NGTC-RNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRNGQCI-NTVGSFQCQCN 1959
Query: 1460 AGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517
G++ +G C IN C + C A C+ R C C GY+ C +I+ C
Sbjct: 1960 EGYEVAPDGRTCVDINECLLEPRKC-APGTCQNLDGSYR-CICPPGYSLQNEKCEDIDEC 2017
Query: 1518 LENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVC--TLINVCLTK--NGGCSEFAICN 1573
+E C G + C + + G+ C ++ C K G CS N
Sbjct: 2018 VEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRN 2077
Query: 1574 HTGQVERTCTCKPNYIGD 1591
H+ Q E C K GD
Sbjct: 2078 HSKQ-ECCCALKGEGWGD 2094
Score = 70.9 bits (172), Expect = 2e-11
Identities = 133/619 (21%), Positives = 199/619 (32%), Gaps = 184/619 (29%)
Query: 1820 KVLAVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDC 1879
K + ++ T W+T+ + +C ++ +NG T ++ + LG A+G C
Sbjct: 842 KTICIETIKGTCWQTV----IDGRC-------EININGAT---LKSQCCSSLGAAWGSPC 887
Query: 1880 LL--IDPTLGG--------RCDTFTTFDA-SGEC--GSCVNTPSCPRWSKPKGVKQKCLY 1926
L +DP G +C+ + G C G CVNT + P G+
Sbjct: 888 TLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATG 947
Query: 1927 NLPFKRNLEGC-----RERCSLVI----QIPRCC----KGYFGRDCQACP---------- 1963
+ LE C E C+L I ++ CC + +C+ CP
Sbjct: 948 RICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEEL 1007
Query: 1964 --------------GGPDAPCNNRGVCLDQYSATGECK---------CNTGF-------N 1993
G P N + G+C+ C++GF N
Sbjct: 1008 CPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERN 1067
Query: 1994 GTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWT---------------- 2037
T + C R PD CG GQC + G +C C+ G+
Sbjct: 1068 CTDIDEC---RISPDL--CG---RGQCVN-TPGDFECKCDEGYESGFMMMKNCMDIDECQ 1118
Query: 2038 --------GPSCDTQAVLPAVCTPPCSAH---ATCKENNTCE------------------ 2068
G +T+ C P + C + N CE
Sbjct: 1119 RDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKY 1178
Query: 2069 ---CNLDYEG--DGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSC 2121
CN Y D + C +D C NGGC C+ CSCQ G+ D SC
Sbjct: 1179 QCACNPGYHSTPDRLFCVDIDECSIMNGGCETF--CTNSEGSYECSCQPGFALMPDQRSC 1236
Query: 2122 TEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
T+ID C D N + C PG+++C C DG + + D +C
Sbjct: 1237 TDIDECED--NPNICDGGQCTNI-PGEYRCLCY-----DGFMASEDM----KTCVDVNEC 1284
Query: 2182 HADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREAC---------ANEAATMATYNQ 2232
+ + T G F +G + K + C A+ A
Sbjct: 1285 DLNPNICLSGTCENTKGSFICHCDMGY---SGKKGKTGCTDINECEIGAHNCGKHAVCTN 1341
Query: 2233 LSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRM 2292
+ + K CS GW+ G C +G + N M
Sbjct: 1342 TAGSFKCS---CSPGWIGDGIKCTDL----DECSNGTHMCSQHADCKNT----------M 1384
Query: 2293 KDVNCTCKVGYVGDGFSCS 2311
C CK GY GDGF+C+
Sbjct: 1385 GSYRCLCKEGYTGDGFTCT 1403
Score = 70.9 bits (172), Expect = 2e-11
Identities = 90/349 (25%), Positives = 138/349 (39%), Gaps = 56/349 (16%)
Query: 40 RTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPR 99
R +C + + KC +GY SG + +++C E + L G +C R
Sbjct: 1083 RGQCVNTPGDFECKCDEGYE---SGFMMMKNCMDIDECQRDPLLCRG--GVCHNTEGSYR 1137
Query: 100 C-CPG--RWGPD---CI---ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
C CP + P+ CI EC A NGR + G C+C G+ T
Sbjct: 1138 CECPPGHQLSPNISACIDINECELSAHLCPNGR---CVNLIGKYQCACNPGYHSTP---- 1190
Query: 151 ADDNLFGPSCSSV--CNCVHGVCNS---GLDGDGTCECYSAYT---GPKCDKPIPECA-- 200
D LF C + C+ ++G C + +G C C + + I EC
Sbjct: 1191 --DRLF---CVDIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDN 1245
Query: 201 ALLCPENSRCSPSTEDENKLECKCLPNYRG--DGKYCDPINPCLRKICHPHAHCTYLGPN 258
+C + +C T + C C + D K C +N C +P+ + N
Sbjct: 1246 PNIC-DGGQC---TNIPGEYRCLCYDGFMASEDMKTCVDVNEC---DLNPNICLSGTCEN 1298
Query: 259 RHS---CTCQEGYRGD-GQV-CLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQN 313
C C GY G G+ C ++ C+I NC K VC + G C C +
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCG-KHAVCT-NTAGSFKCSCSPGWIG 1356
Query: 314 FVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
G+ C+ D C + + C ++A+C G C+C++GY GDG TC
Sbjct: 1357 --DGIKCTDLDECSNGTHMCSQHADCKNTM-GSYRCLCKEGYTGDGFTC 1402
Score = 69.7 bits (169), Expect = 3e-11
Identities = 67/275 (24%), Positives = 100/275 (36%), Gaps = 60/275 (21%)
Query: 100 CCPGR--WGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC--ETCADDNL 155
CC G WGP C CP F GT + C
Sbjct: 2364 CCDGGRGWGPHCEICP----------------------------FQGTVAFKKLCPHGRG 2395
Query: 156 FGPSCSSV--CNCVHGVCNSGL----DGDGTCECYSAYT----GPKCDKPIPECAALLCP 205
F + + + C +H VC +G G C C + YT G C + EC P
Sbjct: 2396 FMTNGADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSC-VDLNECNQAPKP 2454
Query: 206 ENSRCSPSTEDENKLECKCLPNY--RGDGKYCDPINPCLRKICHPHAHCTYLGPNR---H 260
N C + E +C C Y + DG+ C ++ C K +C +L N
Sbjct: 2455 CNFICKNT---EGSYQCSCPKGYILQEDGRSCKDLDECATK----QHNCQFLCVNTIGGF 2507
Query: 261 SCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC 320
+C C G+ C+ + C + C +K +C+ + PG CEC+ + G C
Sbjct: 2508 TCKCPPGFTQHHTSCIDNNECTSDINLCGSKG-ICQ-NTPGSFTCECQRGFSLDQTGSSC 2565
Query: 321 SMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV 355
D C+ ++ C C + G C C +GY+
Sbjct: 2566 EDVDECEGNHRCQH--GCQNII-GGYRCSCPQGYL 2597
Score = 69.3 bits (168), Expect = 5e-11
Identities = 67/239 (28%), Positives = 90/239 (37%), Gaps = 39/239 (16%)
Query: 1371 VCECGEGFSGTACETCTEGKYGIHCDQACS-----CVHGRCNQGPLGDGSCDCDVGWR-G 1424
+C G GF A + T GK C C HG+C + +G C CD G+
Sbjct: 1007 LCPRGPGF---ATKEITNGKPFFKDINECKMIPSLCTHGKC-RNTIGSFKCRCDSGFALD 1062
Query: 1425 VHCDNATTEDNCN--------GTCHTSANCLTNSDGTASCKCAAGFQGNGTI---CTAIN 1473
N T D C G C N+ G CKC G++ + C I+
Sbjct: 1063 SEERNCTDIDECRISPDLCGRGQC-------VNTPGDFECKCDEGYESGFMMMKNCMDID 1115
Query: 1474 ACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINPCLENHGGCDKNAECT 1531
C+ C + T G C C G+ + + C++IN C + C
Sbjct: 1116 ECQRDPLLC--RGGVCHNTEGSYRCECPPGHQLSPNISACIDINECELSAHLCPNGRCVN 1173
Query: 1532 QTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
G Q ACN P Y T D C I+ C NGGC F N G E C+C+P +
Sbjct: 1174 LIGKYQCACN--PGYHSTPDRLFCVDIDECSIMNGGCETFC-TNSEGSYE--CSCQPGF 1227
Score = 66.6 bits (161), Expect = 3e-10
Identities = 81/297 (27%), Positives = 111/297 (37%), Gaps = 62/297 (20%)
Query: 1339 GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGF----SGTACETCTEGKYGIH 1394
GF C N N+C GNG CL+ G CEC GF G ACE E
Sbjct: 1399 GFTCTDLDECSENL-NLC-GNGQCLNAPGGYR-CECDMGFVPSADGKACEDIDE------ 1449
Query: 1395 CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCD-NATTEDNC-NGTCHTSANCLTNSDG 1452
C CV G C+ P G C+C++G+ N T + C + T S NC+ N+ G
Sbjct: 1450 CSLPNICVFGTCHNLP-GLFRCECEIGYELDRSGGNCTDVNECLDPTTCISGNCV-NTPG 1507
Query: 1453 TASCKCAAGFQGNGTICTAIN-------------------ACEISNGGCSAKADC----- 1488
+ C C F+ N T ++ AC G +KA C
Sbjct: 1508 SYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLG 1567
Query: 1489 ------------KRTTPGRRVCTCKAGYTGDGIVCL--EINPCLENHGGCDKNAECTQTG 1534
T+ + +C G+ + I + +I+ C E G C + +C T
Sbjct: 1568 KAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLC-QGGKCINTF 1626
Query: 1535 PNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI 1589
C C Y D +VC +N C T G C N G TC C P+Y+
Sbjct: 1627 -GSFQCRCPTGYYLNEDTRVCDDVNECETP-GICGPGTCYNTVGNY--TCICPPDYM 1679
Score = 66.6 bits (161), Expect = 3e-10
Identities = 61/208 (29%), Positives = 84/208 (40%), Gaps = 19/208 (9%)
Query: 793 LCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS 851
+C +G C N + S C G + D GP C +A C + G+
Sbjct: 1776 VCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPV---CQRNAECINTAGSYR 1832
Query: 852 CICKAGYEGDGT-LCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRD--C 908
C CK GY T C++ + C + P CS + +CI T G+ C+C G+ N C
Sbjct: 1833 CDCKPGYRFTSTGQCNDRNECQEI-PNICS-HGQCIDT-VGSFYCLCHTGFKTNDDQTMC 1889
Query: 909 SEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF-RGNGIDCEPITSCLEQTGKCHPL 967
+IN C + G N +C G C C GF + DC + C G
Sbjct: 1890 LDINECERDACG----NGTCRNT-IGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN 1944
Query: 968 ASCQSTSSGVWSCVCQEGYE--GDGFLC 993
C +T G + C C EGYE DG C
Sbjct: 1945 GQCINTV-GSFQCQCNEGYEVAPDGRTC 1971
Score = 65.5 bits (158), Expect = 7e-10
Identities = 66/220 (30%), Positives = 93/220 (42%), Gaps = 45/220 (20%)
Query: 793 LCVHGTCNNRIDSDGAC-----------LTGTCRDGSAGRLCDKQTSACGPYVQFCHIHA 841
LC +G C I + G+C L G C D C+K A G
Sbjct: 459 LCQNGRC---IPTPGSCRCECNKGFQLDLRGECIDVDE---CEKNPCAGGE--------- 503
Query: 842 TCEYSNGTASCICKAGYEG--DGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQ 899
C + G+ +C C+AGY+ T C ++D C L G N CI T G+ CVC
Sbjct: 504 -CINNQGSYTCQCRAGYQSTLTRTECRDIDEC--LQNGRICNNGRCINT-DGSFHCVCNA 559
Query: 900 GW--TGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR--GNGIDCEPIT 955
G+ T +G++C +++ C S N C+ G +C CK GF+ +G C+ I
Sbjct: 560 GFHVTRDGKNCEDMDEC---SIRNMCLNGMCIN-EDGSFKCICKPGFQLASDGRYCKDIN 615
Query: 956 SCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG--DGFLC 993
C E G C C +T G + C C G DG +C
Sbjct: 616 EC-ETPGICMN-GRCVNT-DGSYRCECFPGLAVGLDGRVC 652
Score = 65.5 bits (158), Expect = 7e-10
Identities = 91/328 (27%), Positives = 115/328 (35%), Gaps = 97/328 (29%)
Query: 108 DCI---ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFG-GTACETCADDN--LFGPSCS 161
DCI EC G G+ C G C + G+ C C EG+ TC D N L P
Sbjct: 1927 DCIDVDECASGNGNLCRN-GQCINTV-GSFQCQCNEGYEVAPDGRTCVDINECLLEPR-- 1982
Query: 162 SVCNCVHGVCNSGLDGDGTCECYSAYT--GPKCDK-----PIPECAAL------------ 202
C G C + LDG C C Y+ KC+ PE AL
Sbjct: 1983 ---KCAPGTCQN-LDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKC 2038
Query: 203 LCPEN-------SRC------------------SPSTEDENKLECKCLPNYRGDGKYCD- 236
LCPE RC SP + + +K EC C G G C+
Sbjct: 2039 LCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCEL 2098
Query: 237 -PINP--CLRKICHPHAHCTYLGPN-------------------------RHSCTCQEGY 268
P P R+IC P+ +GP+ + C C GY
Sbjct: 2099 CPTEPDEAFRQIC-PYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGY 2157
Query: 269 RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICK- 327
G C+ D C + GN P + CK + G C C+E F PG + DI +
Sbjct: 2158 ILAGNECVDTDECSV--GN-PCGNGTCK-NVIGGFECTCEE---GFEPGPMMTCEDINEC 2210
Query: 328 SDNPCHRNANCTTVAPGRTECICQKGYV 355
+ NP C G EC C GYV
Sbjct: 2211 AQNPLLCAFRCVNTY-GSYECKCPVGYV 2237
Score = 65.5 bits (158), Expect = 7e-10
Identities = 62/202 (30%), Positives = 79/202 (39%), Gaps = 39/202 (19%)
Query: 1323 CQPKCVRTVITREC-CAGFFGPQCQPCPGNAQ-----NVCFGNGICLDGVNGTGVCECGE 1376
CQ CV T+ C C F C N + N+C GIC G+ CEC
Sbjct: 2496 CQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGIC-QNTPGSFTCECQR 2554
Query: 1377 GFS----GTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATT 1432
GFS G++CE E C+ C HG C Q +G C C G+ + N
Sbjct: 2555 GFSLDQTGSSCEDVDE------CEGNHRCQHG-C-QNIIGGYRCSCPQGYLQHYQWNQCV 2606
Query: 1433 EDN-------CNG-TCHTSANCLTNSDGTASCKCAAGFQGN--GTICTAINACEISNGGC 1482
++N C G +CH N+ G+ C C AGFQ C IN C + C
Sbjct: 2607 DENECLSAHICGGASCH-------NTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC 2659
Query: 1483 SAKADCKRTTPGRRVCTCKAGY 1504
S T G +C C GY
Sbjct: 2660 SYGCS---NTEGGYLCGCPPGY 2678
Score = 63.2 bits (152), Expect = 3e-09
Identities = 83/328 (25%), Positives = 119/328 (36%), Gaps = 86/328 (26%)
Query: 1902 CGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGR-DCQ 1960
CGS N CP W G Q C+ + CR C G+ R +
Sbjct: 59 CGSRYNAYCCPGWKTLPGGNQ-CIVPI--------CRHSCG---------DGFCSRPNMC 100
Query: 1961 ACPGGPDAP-------------CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGP 2007
CP G AP C N G C D + C C G+ GT C G
Sbjct: 101 TCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDDH-----CLCQKGYIGTHC--------GQ 147
Query: 2008 DCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 2067
GC + G+C +C C G+TGP C+ T PC T N C
Sbjct: 148 PVCESGCLNGGRC----VAPNRCACTYGFTGPQCERD-----YRTGPC---FTVISNQMC 195
Query: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS----CQKGYKGD--GHSC 2121
+ L GI CT C CA V R ++ + C++G+ + +C
Sbjct: 196 QGQL----SGIVCTKT-LC------CATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGAC 244
Query: 2122 TEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
++D C + G C + C T G +C+C + + + ++ + E ID C G C
Sbjct: 245 QDVDEC-QAIPGLC-QGGNCINT-VGSFECKCPAGHKLNEVSQKCED--IDECSTIPGIC 299
Query: 2182 HADAKCVDLHFQDTTVGVFHLRSPLGQY 2209
+C + TV + + P G Y
Sbjct: 300 EG-GECTN------TVSSYFCKCPPGFY 320
Score = 63.2 bits (152), Expect = 3e-09
Identities = 60/203 (29%), Positives = 81/203 (39%), Gaps = 18/203 (8%)
Query: 1401 CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAA 1460
C +GRC P G C+C+ G++ D C C+ N+ G+ +C+C A
Sbjct: 460 CQNGRCIPTP-GSCRCECNKGFQLDLRGECIDVDECEKNPCAGGECI-NNQGSYTCQCRA 517
Query: 1461 GFQG--NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINP 1516
G+Q T C I+ C + NG C T G C C AG+ T DG C +++
Sbjct: 518 GYQSTLTRTECRDIDEC-LQNGRICNNGRC-INTDGSFHCVCNAGFHVTRDGKNCEDMDE 575
Query: 1517 CLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNH 1574
C + N C C C P + DG+ C IN C T G C N
Sbjct: 576 C--SIRNMCLNGMCINE-DGSFKCICKPGFQLASDGRYCKDINECETP-GICMNGRCVNT 631
Query: 1575 TGQVERTCTCKPNY-IG-DGFTC 1595
G C C P +G DG C
Sbjct: 632 DGSYR--CECFPGLAVGLDGRVC 652
Score = 63.2 bits (152), Expect = 3e-09
Identities = 86/307 (28%), Positives = 113/307 (36%), Gaps = 81/307 (26%)
Query: 728 CCKGF-YGPDCNQCPG---GFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNK 783
C KGF Y PD C S+PC NG C +S G+ ICE CS +
Sbjct: 792 CPKGFIYKPDLKTCEDIDECESSPCI-NGVCKNS---PGSFICE----------CSSEST 837
Query: 784 YGPRCNKKCLCVH---GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH 840
P K +C+ GTC + DG C + C +A G C +
Sbjct: 838 LDPT---KTICIETIKGTCWQTV-IDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVD 893
Query: 841 ATCEYSNGTASCICKAGYEG-DGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQ 899
IC GY GT C ++D C + PG C +N C+ T G+ C C
Sbjct: 894 P-----------ICGKGYSRIKGTQCEDIDECE-VFPGVC-KNGLCVNT-RGSFKCQCPS 939
Query: 900 GWT--GNGRDCSEIN-----------NCLLPSAGGCHDNASCLYVGP--GQNECE----- 939
G T GR C +I C LP AG +A C VG G ECE
Sbjct: 940 GMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMR 999
Query: 940 --------CKKGFRGNGIDCEPITS---CLEQTGKCHPLAS------CQSTSSGVWSCVC 982
C RG G + IT+ + +C + S C++T G + C C
Sbjct: 1000 NTPEYEELCP---RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNT-IGSFKCRC 1055
Query: 983 QEGYEGD 989
G+ D
Sbjct: 1056 DSGFALD 1062
Score = 62.0 bits (149), Expect = 7e-09
Identities = 90/329 (27%), Positives = 122/329 (37%), Gaps = 75/329 (22%)
Query: 99 RC-CPGRW---GPDCI---ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCA 151
RC CP + G +C+ EC G+PC G G+C + + G C+C+EGF TC
Sbjct: 2150 RCECPFGYILAGNECVDTDEC--SVGNPC-GNGTC-KNVIGGFECTCEEGFEPGPMMTCE 2205
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS 211
D N + C N+ G C+C Y + + +C + C
Sbjct: 2206 DIN---ECAQNPLLCAFRCVNT--YGSYECKCPVGYVLREDRR--------MCKDEDECE 2252
Query: 212 PSTED--ENKLECK---------CLPNY--RGDGKYCDPINPCLRK--ICHPHAHCTYLG 256
D E ++ECK C P Y R DG+ C N C K IC + C
Sbjct: 2253 EGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICE-NGRCLNT- 2310
Query: 257 PNRHSCTCQEGYRG--DGQVCLP-----------VDPCQINFG--NCPTKSTVCKYDGPG 301
++C C +G+ + CL + CQI N TKS C G G
Sbjct: 2311 RGSYTCECNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRG 2370
Query: 302 QS-HCEC-----KEHYQNFVPGVGCSMT-----DICKSDNPCHRNANCTTVAPGRTECIC 350
HCE ++ P MT D CK + RN C G CIC
Sbjct: 2371 WGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVN-DRGSYHCIC 2429
Query: 351 QKGYVGD--GLTCYGNIMERLRELNTEPR 377
+ GY D G +C L E N P+
Sbjct: 2430 KTGYTPDITGTSCVD-----LNECNQAPK 2453
Score = 60.8 bits (146), Expect = 2e-08
Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 38/231 (16%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCV 795
D N+C GNG C +++G + C C GF S C D ++ LC
Sbjct: 1891 DINEC----ERDACGNGTCRNTIG-SFNCRCNHGFILSHNNDCIDVDECASGNGN--LCR 1943
Query: 796 HGTCNNRIDS-DGACLTG--------TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS 846
+G C N + S C G TC D + C + C P TC+
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINE---CLLEPRKCAP--------GTCQNL 1992
Query: 847 NGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGN 904
+G+ CIC GY C ++D C P C+ C T G+ C+C +G+ + +
Sbjct: 1993 DGSYRCICPPGYSLQNEKCEDIDECVE-EPEICALGT-CSNT-EGSFKCLCPEGFSLSSS 2049
Query: 905 GRDCSEI--NNCLLPSAGG-CHDNASCLYVGPGQNECECKKGFRGNGIDCE 952
GR C ++ + C GG C S + + EC C G G CE
Sbjct: 2050 GRRCQDLRMSYCYAKFEGGKCSSPKSRNH---SKQECCCALKGEGWGDPCE 2097
Score = 60.1 bits (144), Expect = 3e-08
Identities = 75/277 (27%), Positives = 102/277 (36%), Gaps = 58/277 (20%)
Query: 1336 CCAGFF----GPQCQPCPG-NAQNVCFGNGICLDGVNGTGVCECGEGFS----GTACETC 1386
C AGF G C+ + +N+C NG+C++ +G+ C C GF G C+
Sbjct: 557 CNAGFHVTRDGKNCEDMDECSIRNMCL-NGMCINE-DGSFKCICKPGFQLASDGRYCKDI 614
Query: 1387 TEGKYGIHCDQACSCVHGRCNQGPLGDGSCDC----DVGWRGVHCDNATTEDNCNGTCHT 1442
E C+ C++GRC G C+C VG G C + C G +
Sbjct: 615 NE------CETPGICMNGRCVNTD-GSYRCECFPGLAVGLDGRVCVDTHMRSTCYGG-YK 666
Query: 1443 SANCLTNSDGTAS---CKCAAGFQGNGTICTAINA---------CEISNGGCSAKADCKR 1490
C+ G + C CA+ G C A C G SA +D
Sbjct: 667 RGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINE 726
Query: 1491 TT--------------PGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKNAECTQTG 1534
G C C +GY D G C++IN C+ N CD N +C T
Sbjct: 727 CALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCD-NGQCRNT- 784
Query: 1535 PNQAACNCLPA--YTGDGKVCTLINVCLTK---NGGC 1566
P C C Y D K C I+ C + NG C
Sbjct: 785 PGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGVC 821
Score = 59.7 bits (143), Expect = 4e-08
Identities = 76/291 (26%), Positives = 103/291 (35%), Gaps = 50/291 (17%)
Query: 1998 EMCWPGRFGPDCLPCGCSDHGQ-----CDDG--ITGSGQCLCETGWTGPSCDTQAVLPAV 2050
E +P R P LP +D+ Q C +G I G C CE G D + V
Sbjct: 433 EYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECN-KGFQLDLRGECIDV 491
Query: 2051 --CTPPCSAHATCKENN---TCECNLDYEG--DGITCTVVDFCKQDNGGCAKVARCSQKG 2103
C A C N TC+C Y+ C +D C Q NG RC
Sbjct: 492 DECEKNPCAGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQ-NGRICNNGRCINTD 550
Query: 2104 TKVSCSCQKGY--KGDGHSCTEIDPCADG---LNGGCHEHATCKMTGPGKHKCECK---- 2154
C C G+ DG +C ++D C+ LNG C + G KC CK
Sbjct: 551 GSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMC-------INEDGSFKCICKPGFQ 603
Query: 2155 ----SHYVGDGLNCEPEQLPID-RCLQDNGQCHADA-----------KCVDLHFQDTTVG 2198
Y D CE + ++ RC+ +G + CVD H + T G
Sbjct: 604 LASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYG 663
Query: 2199 VFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQ-KAKYH-LCSAG 2247
+ + K+ CA+ Q AQ A+Y LCS+G
Sbjct: 664 GYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSG 714
Score = 57.4 bits (137), Expect = 2e-07
Identities = 73/333 (21%), Positives = 110/333 (33%), Gaps = 107/333 (32%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCV 167
+CI+ +PC G G C +G+ TC C+ G+ T T C + C+
Sbjct: 487 ECIDVDECEKNPCAG-GECINN-QGSYTCQCRAGYQSTLTRT---------ECRDIDECL 535
Query: 168 HG--VCNSG----LDGDGTCECYSAY----TGPKCDKPIPECAALLCPENSRCSPSTEDE 217
+CN+G DG C C + + G C+ + EC+ N C ++
Sbjct: 536 QNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCED-MDECSIRNMCLNGMC---INED 591
Query: 218 NKLECKCLPNYR--GDGKYCDPINPCLRKICHPHAHCTYL-GPNRHSC------------ 262
+C C P ++ DG+YC IN C + C G R C
Sbjct: 592 GSFKCICKPGFQLASDGRYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRV 651
Query: 263 --------TCQEGYRGDGQVCLPV-------------------DPCQINFGNCPTKST-- 293
TC GY+ GQ P+ +PCQ CP +++
Sbjct: 652 CVDTHMRSTCYGGYKR-GQCIKPLFGAVTKSECCCASTEYAFGEPCQ----PCPAQNSAE 706
Query: 294 ---VCKYDGPGQSH----------------------------CECKEHYQNFVPGVGCSM 322
+C GPG + C C Y+ G C
Sbjct: 707 YQALCS-SGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Query: 323 TDICKSDNPCHRNANCTTVAPGRTECICQKGYV 355
+ C ++ N C PG C C KG++
Sbjct: 766 INECVLNSLLCDNGQCRNT-PGSFVCTCPKGFI 797
Score = 57.4 bits (137), Expect = 2e-07
Identities = 76/309 (24%), Positives = 104/309 (33%), Gaps = 60/309 (19%)
Query: 726 PKCCKGFYGPDCNQCPGGFS---NPCSGNGQCAD-----SLG------GNGTCICEEGFQ 771
P C+ G CP G+S C +C + +LG G+ C+C EGF
Sbjct: 1986 PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFS 2045
Query: 772 ----GSQCQF--------------CSDPNKYGPRCNKKCLCVHGT-----CNNRIDSDGA 808
G +CQ CS P + C + G C
Sbjct: 2046 LSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDE 2105
Query: 809 CLTGTCRDGSAGRLCDKQTSACG----PYVQFCHIHATCEYSNGTASCICKAGYEGDGTL 864
C GS G + SA C H C ++G+ C C GY G
Sbjct: 2106 AFRQICPYGS-GIIVGPDDSAVDMDECKEPDVCK-HGQCINTDGSYRCECPFGYILAGNE 2163
Query: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW-TGNGRDCSEINNCL---LPSAG 920
C + D C+ P G N C K G C C++G+ G C +IN C L A
Sbjct: 2164 CVDTDECSVGNPCG---NGTC-KNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAF 2219
Query: 921 GCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
C + G EC+C G+ R + C+ C E C G +
Sbjct: 2220 RCVNTY-------GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTY 2272
Query: 979 SCVCQEGYE 987
C+C GY+
Sbjct: 2273 MCICGPGYQ 2281
Score = 55.5 bits (132), Expect = 7e-07
Identities = 48/151 (31%), Positives = 65/151 (43%), Gaps = 14/151 (9%)
Query: 1452 GTASCKCAAGFQGN-GTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDG 1508
G+ C+C GFQ + C ++ CE C A +C G C C+AGY T
Sbjct: 470 GSCRCECNKGFQLDLRGECIDVDECE--KNPC-AGGECINNQ-GSYTCQCRAGYQSTLTR 525
Query: 1509 IVCLEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCS 1567
C +I+ CL+N C+ N C T G CN T DGK C ++ C +N C
Sbjct: 526 TECRDIDECLQNGRICN-NGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRN-MCL 583
Query: 1568 EFAICNHTGQVERTCTCKPNY--IGDGFTCR 1596
N G + C CKP + DG C+
Sbjct: 584 NGMCINEDGSFK--CICKPGFQLASDGRYCK 612
Score = 54.7 bits (130), Expect = 1e-06
Identities = 77/358 (21%), Positives = 119/358 (33%), Gaps = 53/358 (14%)
Query: 31 CDRKSLLTIRTECRSCALNLG-------VKCPDGYTMITSGSVGVRDCRYTFEVRT-YSL 82
CD + L + + C+ N+G +CP T + G + + ++ T +
Sbjct: 1706 CDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPV 1765
Query: 83 SLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGA-----------------GSPCNGRGS 125
+ CR I + C G ECP G G C
Sbjct: 1766 DIDECREI--PGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE 1823
Query: 126 CAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN-CVHGVCNSGLDGDGTCECY 184
C G+ C C+ G+ T+ C D N C + N C HG C +D G+ C
Sbjct: 1824 CIN-TAGSYRCDCKPGYRFTSTGQCNDRN----ECQEIPNICSHGQC---IDTVGSFYCL 1875
Query: 185 SAYTGPKCDKPIPECAALLCPENSRCSPST--EDENKLECKCLPNY-RGDGKYCDPINPC 241
+TG K + C + E C T C+C + C ++ C
Sbjct: 1876 -CHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDEC 1934
Query: 242 LR---KICHPHAHCTYLGPNRHSCTCQEGYR--GDGQVCLPVDPCQINFGNCPTKSTVCK 296
+C +G C C EGY DG+ C+ ++ C + C T
Sbjct: 1935 ASGNGNLCRNGQCINTVG--SFQCQCNEGYEVAPDGRTCVDINECLLEPRKC-APGTCQN 1991
Query: 297 YDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
D G C C Y + C D C + C+ G +C+C +G+
Sbjct: 1992 LD--GSYRCICPPGYS--LQNEKCEDIDECVEEPEICALGTCSN-TEGSFKCLCPEGF 2044
Score = 52.8 bits (125), Expect = 4e-06
Identities = 62/274 (22%), Positives = 87/274 (31%), Gaps = 62/274 (22%)
Query: 1956 GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCS 2015
G D C D C N G C++ + C C TG+ PD C
Sbjct: 2400 GADIDECKVIHDV-CRN-GECVNDRGSY-HCICKTGYT-------------PDITGTSCV 2443
Query: 2016 DHGQCDDG----------ITGSGQCLCETGWT----GPSCDTQAVLPAVCTPPCSAHATC 2061
D +C+ GS QC C G+ G SC L T + C
Sbjct: 2444 DLNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSCKD---LDECATKQHNCQFLC 2500
Query: 2062 KENN---TCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGD- 2117
TC+C + +C + C D C C +C CQ+G+ D
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDQ 2560
Query: 2118 -GHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQ 2176
G SC ++D C G H+C+ + G C Q +
Sbjct: 2561 TGSSCEDVDEC------------------EGNHRCQHGCQNIIGGYRCSCPQGYLQH--Y 2600
Query: 2177 DNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYK 2210
QC + +C+ H G + LG YK
Sbjct: 2601 QWNQCVDENECLSAHI----CGGASCHNTLGSYK 2630
Score = 52.4 bits (124), Expect = 6e-06
Identities = 88/370 (23%), Positives = 120/370 (32%), Gaps = 116/370 (31%)
Query: 100 CCP--GR-WGPDCIECPGGAGSPCNG-------RGSCAEGMEGN---GTC---SCQEGFG 143
CC GR WG C CP PC G+C + E G C +C G
Sbjct: 209 CCATVGRAWGHPCEMCPAQP-HPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVG 267
Query: 144 GTACETCADDNL--FGPSCSSV--CNCVHGVCNSG------------------LDGDGT- 180
C+ A L C + C+ + G+C G DGT
Sbjct: 268 SFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTR 327
Query: 181 C------ECYSAYTGPKCDKPIPECAALL--CPENSRC-SP------------STEDENK 219
C CY+A T +C +P+ + C + RC SP +TED NK
Sbjct: 328 CIDVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 220 LECKCLPNYRGDGKY----CDPINPCL---------RKICHPHAHCTYLGPNRH------ 260
L C G +Y PI P L +I P YL P+R
Sbjct: 388 L-CSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLP 446
Query: 261 --------------------------SCTCQEGYRGDGQ-VCLPVDPCQINFGNCPTKST 293
C C +G++ D + C+ VD C+ N P
Sbjct: 447 VNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKN----PCAGG 502
Query: 294 VCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKG 353
C + G C+C+ YQ+ + C D C + N C G C+C G
Sbjct: 503 EC-INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCIN-TDGSFHCVCNAG 560
Query: 354 Y--VGDGLTC 361
+ DG C
Sbjct: 561 FHVTRDGKNC 570
Score = 51.6 bits (122), Expect = 1e-05
Identities = 83/347 (23%), Positives = 121/347 (34%), Gaps = 97/347 (27%)
Query: 675 GTCVSCSLVYWSRCPANSEPTALFTH-----RCVYSGRFGSLKSGCAR-------YCNAT 722
G C++ Y +C A + T T C+ +GR + C CNA
Sbjct: 502 GECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCINTDGSFHCVCNAG 560
Query: 723 VKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQ-GSQCQFCSDP 781
+ + K D ++C N C NG C + G+ CIC+ GFQ S ++C D
Sbjct: 561 FHVTRDGKNC--EDMDEC--SIRNMCL-NGMCINE-DGSFKCICKPGFQLASDGRYCKDI 614
Query: 782 NK-------YGPRC-----NKKCLCVHG-----------------TCNNRID-------- 804
N+ RC + +C C G TC
Sbjct: 615 NECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPL 674
Query: 805 ------SDGACLTGTCRDGSAGRLCDKQTSA--------------CGPYVQFCHI----- 839
S+ C + G + C Q SA G + C +
Sbjct: 675 FGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDIC 734
Query: 840 -HATCEYSNGTASCICKAGYEGD--GTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCV 896
+ CE GT CIC +GYE D G C +++ C L C N +C T G+ C
Sbjct: 735 PNGICENLRGTYKCICNSGYEVDSTGKNCVDINECV-LNSLLCD-NGQCRNT-PGSFVCT 791
Query: 897 CQQG--WTGNGRDCSEINNC-LLPSAGGCHDNASCLYVGPGQNECEC 940
C +G + + + C +I+ C P G N+ PG CEC
Sbjct: 792 CPKGFIYKPDLKTCEDIDECESSPCINGVCKNS------PGSFICEC 832
Score = 49.7 bits (117), Expect = 4e-05
Identities = 65/265 (24%), Positives = 91/265 (34%), Gaps = 65/265 (24%)
Query: 1958 DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE-MCWPGRFG---PDCLPCG 2013
+CQ PG C N G CL+ + C+CN GF + + C R G + L
Sbjct: 2294 ECQTKPG----ICEN-GRCLNTRGSY-TCECNDGFTASPNQDECLDNREGYCFTEVLQNM 2347
Query: 2014 CSDHGQCDDGITGSGQCLCE--TGWTGPSCDT-----QAVLPAVCT------------PP 2054
C + +T S +C C+ GW GP C+ +C
Sbjct: 2348 CQIGSSNRNPVTKS-ECCCDGGRGW-GPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDE 2405
Query: 2055 CSA-HATCKENNT--------CECNLDYEGD--GITCTVVDFCKQDNGGCAKVARCSQKG 2103
C H C+ C C Y D G +C ++ C Q C + C
Sbjct: 2406 CKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNFI--CKNTE 2463
Query: 2104 TKVSCSCQKGY--KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCE--CKSHYVG 2159
CSC KGY + DG SC ++D CA +H C+ C + G
Sbjct: 2464 GSYQCSCPKGYILQEDGRSCKDLDECA-----------------TKQHNCQFLCVNTIGG 2506
Query: 2160 DGLNCEPEQLPIDRCLQDNGQCHAD 2184
C P DN +C +D
Sbjct: 2507 FTCKCPPGFTQHHTSCIDNNECTSD 2531
Score = 49.3 bits (116), Expect = 5e-05
Identities = 81/336 (24%), Positives = 110/336 (32%), Gaps = 107/336 (31%)
Query: 1280 IRGRCRTCSSELTCP-FGTKSLGNEKRRCIYTSYFMGRRTLFIGCQP-KCVR----TVIT 1333
+ GRC C F ++G + R C+ T R T + G + +C++ V
Sbjct: 624 MNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHM---RSTCYGGYKRGQCIKPLFGAVTK 680
Query: 1334 RECCAGF----FGPQCQPCP--------------------GNAQNVCF------GNGICL 1363
ECC FG CQPCP G+ N C NGIC
Sbjct: 681 SECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGIC- 739
Query: 1364 DGVNGTGVCECGEGF----SGTACETCTEGKYG-IHCDQA----------CSCVHG---- 1404
+ + GT C C G+ +G C E + CD C+C G
Sbjct: 740 ENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYK 799
Query: 1405 ----------RCNQGPLGDGSCDCDVGWRGVHCDNATTED--------NCNGTCHTSA-- 1444
C P +G C G C + +T D GTC +
Sbjct: 800 PDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVID 859
Query: 1445 -NCLTNSDGTAS------------------CK----CAAGFQG-NGTICTAINACEISNG 1480
C N +G C+ C G+ GT C I+ CE+ G
Sbjct: 860 GRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPG 919
Query: 1481 GCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEI 1514
C K T G C C +G T D G +CL+I
Sbjct: 920 VC--KNGLCVNTRGSFKCQCPSGMTLDATGRICLDI 953
Score = 48.5 bits (114), Expect = 8e-05
Identities = 65/264 (24%), Positives = 87/264 (32%), Gaps = 76/264 (28%)
Query: 1374 CGEGFSG--TACETCTEGKYGIHCD----QACSCVHGRC-NQGPLGDGSCDCDVGWRGVH 1426
CG+GF C TC G+ C Q C+ RC N G D C C G+ G H
Sbjct: 89 CGDGFCSRPNMC-TCPSGQIAPSCGSRSIQHCNI---RCMNGGSCSDDHCLCQKGYIGTH 144
Query: 1427 CDNATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGF----------------QGNGTIC 1469
C E C NG + N + G +C + Q +G +C
Sbjct: 145 CGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 1470 TAINAC---------------------------EISNGGCSAKADCKR-----------T 1491
T C I G C +C+
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCIN 264
Query: 1492 TPGRRVCTCKAGYTGDGI--VCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY--T 1547
T G C C AG+ + + C +I+ C G C+ ECT T + C C P + +
Sbjct: 265 TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICE-GGECTNT-VSSYFCKCPPGFYTS 322
Query: 1548 GDGKVCTLI--NVCLT--KNGGCS 1567
DG C + C T NG CS
Sbjct: 323 PDGTRCIDVRPGYCYTALTNGRCS 346
Score = 48.1 bits (113), Expect = 1e-04
Identities = 89/392 (22%), Positives = 126/392 (32%), Gaps = 84/392 (21%)
Query: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI 90
C SLL +CR+ + CP G+ ++ C E S P +
Sbjct: 769 CVLNSLLCDNGQCRNTPGSFVCTCPKGFIY----KPDLKTCEDIDECE----SSPCINGV 820
Query: 91 CRKDYLQPRC-CPGRWGPD-----CIECPGGAGSPCNGRGSCAEGMEG----NGTCSCQE 140
C+ C C D CIE G G C + G + CS
Sbjct: 821 CKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLG 880
Query: 141 GFGGTACETCADDNLFGPSCSSV----------CNCVHGVCNSGL----DGDGTCECYSA 186
G+ C C D + G S + C GVC +GL G C+C S
Sbjct: 881 AAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVCKNGLCVNTRGSFKCQCPSG 940
Query: 187 Y----TGPKC-DKPIPECAALLCPENSRCSPSTEDENKLECKC----------------- 224
TG C D + C L E+ C+ ++++ C
Sbjct: 941 MTLDATGRICLDIRLETC--FLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPM 998
Query: 225 --LPNY-----RGDG----------KYCDPINPC--LRKICHPHAHCTYLGPNRHSCTCQ 265
P Y RG G + IN C + +C H C C C
Sbjct: 999 RNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLC-THGKCRNT-IGSFKCRCD 1056
Query: 266 EGYRGDGQV--CLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQN-FVPGVGCSM 322
G+ D + C +D C+I+ C V + PG C+C E Y++ F+ C
Sbjct: 1057 SGFALDSEERNCTDIDECRISPDLCGRGQCV---NTPGDFECKCDEGYESGFMMMKNCMD 1113
Query: 323 TDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
D C+ D R C G C C G+
Sbjct: 1114 IDECQRDPLLCRGGVCHN-TEGSYRCECPPGH 1144
Score = 48.1 bits (113), Expect = 1e-04
Identities = 72/293 (24%), Positives = 101/293 (34%), Gaps = 55/293 (18%)
Query: 100 CCPGR-WGPDC------------IECPGGAGSPCNGRGSCAEGM----EGNGTCS---CQ 139
C G+ WG C I CPGG G N E + E G C C
Sbjct: 1564 CSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCI 1623
Query: 140 EGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPEC 199
FG C + + VC+ V+ G+ G GTC Y+ C P
Sbjct: 1624 NTFGSFQCR--CPTGYYLNEDTRVCDDVNECETPGICGPGTC--YNTVGNYTCICP---- 1675
Query: 200 AALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDP--INPCLRKIC----------- 246
P+ + + + C NY D + CD + +K+C
Sbjct: 1676 -----PDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWN 1730
Query: 247 HPHAHCTYLGPNRHSCTC---QEGYRGDGQVCLPVD--PCQINFGNCPTKSTVCKYDGPG 301
P C + + C + G+ D LPVD C+ G C ++ VC + G
Sbjct: 1731 KPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC--ENGVC-INMVG 1787
Query: 302 QSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
CEC + + C D C++ C RNA C A G C C+ GY
Sbjct: 1788 SFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTA-GSYRCDCKPGY 1839
Score = 47.8 bits (112), Expect = 1e-04
Identities = 54/209 (25%), Positives = 72/209 (34%), Gaps = 39/209 (18%)
Query: 1336 CCAGFFGPQC-QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE---------- 1384
C G+ G C QP ++ C G C+ C C GF+G CE
Sbjct: 136 CQKGYIGTHCGQPV---CESGCLNGGRCV----APNRCACTYGFTGPQCERDYRTGPCFT 188
Query: 1385 -----TCTEGKYGIHCDQA-CSCVHGR-----CNQGPLGDGSCDCDV--GWRGVHCDNAT 1431
C GI C + C GR C P C R C +
Sbjct: 189 VISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVD 248
Query: 1432 TEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGN--GTICTAINACEISNGGCSAKADCK 1489
G C NC+ N+ G+ CKC AG + N C I+ C G C +C
Sbjct: 249 ECQAIPGLCQ-GGNCI-NTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEG-GECT 305
Query: 1490 RTTPGRRVCTCKAGY--TGDGIVCLEINP 1516
T C C G+ + DG C+++ P
Sbjct: 306 NTV-SSYFCKCPPGFYTSPDGTRCIDVRP 333
Score = 47.8 bits (112), Expect = 1e-04
Identities = 65/261 (24%), Positives = 97/261 (37%), Gaps = 56/261 (21%)
Query: 1949 RCCKGYF---GRDC---QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWP 2002
RC G+ DC C G C N G C++ + +C+CN G+ E+
Sbjct: 1915 RCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSF-QCQCNEGY-----EVAPD 1967
Query: 2003 GRFGPD---CL--PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA 2057
GR D CL P C+ G C + + GS +C+C G++ + + + V P A
Sbjct: 1968 GRTCVDINECLLEPRKCAP-GTCQN-LDGSYRCICPPGYSLQNEKCEDIDECVEEPEICA 2025
Query: 2058 HATCKENN---TCEC----NLDYEGDGITCTVVDFC--KQDNGGCAKVARCSQKGTKVSC 2108
TC C C +L G + +C K + G C+ S+ +K C
Sbjct: 2026 LGTCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPK--SRNHSKQEC 2083
Query: 2109 SCQKGYKGDGHSC-----------TEIDPCADGLNGG----------CHEHATCK----M 2143
C +G G C +I P G+ G C E CK +
Sbjct: 2084 CCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCI 2143
Query: 2144 TGPGKHKCECKSHYVGDGLNC 2164
G ++CEC Y+ G C
Sbjct: 2144 NTDGSYRCECPFGYILAGNEC 2164
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/296 (22%), Positives = 93/296 (31%), Gaps = 55/296 (18%)
Query: 98 PRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
P C R+ C CPG P G C + + SC +GF
Sbjct: 56 PNVCGSRYNAYC--CPGWKTLP--GGNQCIVPICRH---SCGDGFCSRPNMCTCPSGQIA 108
Query: 158 PSCSS--VCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC-SPST 214
PSC S + +C N G D C C Y G C +P+ E C RC +P+
Sbjct: 109 PSCGSRSIQHCNIRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESG---CLNGGRCVAPN- 164
Query: 215 EDENKLECKCLPNYRGDGKYCD---PINPCLRKI-------------CHPHAHCTYLGPN 258
+C Y G C+ PC I C C +G
Sbjct: 165 --------RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRA 216
Query: 259 -RHSC--------TCQEGYRGDGQ--VCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
H C C+ G+ + + C VD CQ G C + + + G C+C
Sbjct: 217 WGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCI---NTVGSFECKC 273
Query: 308 KEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV--GDGLTC 361
++ C D C + CT C C G+ DG C
Sbjct: 274 PAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYF-CKCPPGFYTSPDGTRC 328
Score = 45.1 bits (105), Expect = 0.001
Identities = 54/215 (25%), Positives = 78/215 (36%), Gaps = 50/215 (23%)
Query: 728 CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
C KG+ G C Q C G C G+C C C GF G QC+ + G
Sbjct: 136 CQKGYIGTHCGQPVCESG----CLNGGRCV----APNRCACTYGFTGPQCE---RDYRTG 184
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGR-------LCDKQ------------ 826
P C V + G T T + GR +C Q
Sbjct: 185 P-----CFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNI 239
Query: 827 -TSACGPYVQFCHIHATCEYSN-----GTASCICKAGYEGD--GTLCSEMDPCTGLTPGG 878
T AC + I C+ N G+ C C AG++ + C ++D C+ + PG
Sbjct: 240 RTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTI-PGI 298
Query: 879 CSRNAECIKTGTGTHTCVCQQGW--TGNGRDCSEI 911
C EC T ++ C C G+ + +G C ++
Sbjct: 299 C-EGGECTNT-VSSYFCKCPPGFYTSPDGTRCIDV 331
Score = 45.1 bits (105), Expect = 0.001
Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 28/213 (13%)
Query: 164 CNCVHGVCNSG--LDGDGTCECYSAYTGPKCDKPIP-----ECAALLCPENSRCSPST-- 214
C V +C +G + G+C C +C+K EC + E + C+
Sbjct: 453 CQLVRYLCQNGRCIPTPGSCRC-------ECNKGFQLDLRGECIDVDECEKNPCAGGECI 505
Query: 215 EDENKLECKCLPNYRGD--GKYCDPINPCLR--KICHPHAHCTYLGPNRHSCTCQEGYR- 269
++ C+C Y+ C I+ CL+ +IC+ + C + H C C G+
Sbjct: 506 NNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICN-NGRCINTDGSFH-CVCNAGFHV 563
Query: 270 -GDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS 328
DG+ C +D C I N DG + C CK +Q G C + C++
Sbjct: 564 TRDGKNCEDMDECSIR--NMCLNGMCINEDGSFK--CICKPGFQLASDGRYCKDINECET 619
Query: 329 DNPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
C T R EC DG C
Sbjct: 620 PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC 652
Score = 43.9 bits (102), Expect = 0.002
Identities = 62/249 (24%), Positives = 85/249 (34%), Gaps = 42/249 (16%)
Query: 43 CRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDY--LQPRC 100
C++ + CP GY + G R C+ E T + C+ +C +C
Sbjct: 2459 CKNTEGSYQCSCPKGYILQEDG----RSCKDLDECATKQHN---CQFLCVNTIGGFTCKC 2511
Query: 101 CPG--RWGPDCI---ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFG----GTACETCA 151
PG + CI EC C +G C + G+ TC CQ GF G++CE
Sbjct: 2512 PPGFTQHHTSCIDNNECTSDINL-CGSKGIC-QNTPGSFTCECQRGFSLDQTGSSCEDVD 2569
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCEC----YSAYTGPKCDKPIPECAALLCPEN 207
+ C C HG N + G C C Y +C +A +C
Sbjct: 2570 E-------CEGNHRCQHGCQN--IIGGYRCSCPQGYLQHYQWNQCVDENECLSAHIC--G 2618
Query: 208 SRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNR---HSCTC 264
+T K C Y C IN C A C+Y N + C C
Sbjct: 2619 GASCHNTLGSYKCMCPAGFQYEQFSGGCQDINEC----GSAQAPCSYGCSNTEGGYLCGC 2674
Query: 265 QEGYRGDGQ 273
GY GQ
Sbjct: 2675 PPGYFRIGQ 2683
Score = 43.5 bits (101), Expect = 0.003
Identities = 49/173 (28%), Positives = 67/173 (38%), Gaps = 25/173 (14%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQC-QFCSDPNKYGPRCNKKCLC 794
D N+C N C G C ++ G+ TC C+ GF Q C D ++ C C
Sbjct: 2524 DNNECTSDI-NLCGSKGICQNT-PGSFTCECQRGFSLDQTGSSCEDVDE----CEGNHRC 2577
Query: 795 VHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH----ATCEYSNGTA 850
HG C N I G G L Q + C + H A+C + G+
Sbjct: 2578 QHG-CQNIIG-------GYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSY 2629
Query: 851 SCICKAG--YEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW 901
C+C AG YE C +++ C G CS C T G + C C G+
Sbjct: 2630 KCMCPAGFQYEQFSGGCQDINEC-GSAQAPCSYG--CSNT-EGGYLCGCPPGY 2678
Score = 42.0 bits (97), Expect = 0.008
Identities = 58/243 (23%), Positives = 84/243 (34%), Gaps = 56/243 (23%)
Query: 781 PNKYGPRCNKKCL-----------CVHGTCNNRIDSDGACLTG---TCRDGSAGRLCDKQ 826
PN G R N C C+ C + DG C TC G C +
Sbjct: 56 PNVCGSRYNAYCCPGWKTLPGGNQCIVPICRHSC-GDGFCSRPNMCTCPSGQIAPSCGSR 114
Query: 827 TSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECI 886
+ +Q C+I S C+C+ GY GT C + + GC C+
Sbjct: 115 S------IQHCNIRCMNGGSCSDDHCLCQKGY--IGTHCGQ-----PVCESGCLNGGRCV 161
Query: 887 KTGTGTHTCVCQQGWTG--------NGRDCSEINNCLLP---SAGGCHDNASCLYVGPG- 934
+ C C G+TG G + I+N + S C C VG
Sbjct: 162 ----APNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAW 217
Query: 935 QNECE--------CKKGFRGN--GIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQE 984
+ CE C++GF N C+ + C G C +C +T G + C C
Sbjct: 218 GHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQG-GNCINT-VGSFECKCPA 275
Query: 985 GYE 987
G++
Sbjct: 276 GHK 278
Score = 40.0 bits (92), Expect = 0.029
Identities = 67/301 (22%), Positives = 110/301 (36%), Gaps = 81/301 (26%)
Query: 746 NPCSGNGQCADSLGG--NGTC-------ICEEGF---QGSQCQFCSDPNKYGPRCNKKCL 793
N + QC SLG C IC +G+ +G+QC+ + + C K L
Sbjct: 867 NGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFPGVC-KNGL 925
Query: 794 CVHGTCNNRIDSDGACLTGTCRDGSAGRLC-DKQTSACGPYVQFCHIHATCEYS--NGTA 850
CV N R C +G D + GR+C D + C ++++ T + +
Sbjct: 926 CV----NTRGSFKCQCPSGMTLDAT-GRICLDIRLETC--FLRYEDEECTLPIAGRHRMD 978
Query: 851 SCICKAGYEGDGTLCSE---------------------------------MDPCTGLTPG 877
+C C G C E ++ C + P
Sbjct: 979 ACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECK-MIPS 1037
Query: 878 GCSRNAECIKTGTGTHTCVCQQGWT--GNGRDCSEINNCLL-PSAGGCHDNASCLYVGPG 934
C+ + +C T G+ C C G+ R+C++I+ C + P G C+ PG
Sbjct: 1038 LCT-HGKCRNT-IGSFKCRCDSGFALDSEERNCTDIDECRISPDLCG---RGQCVNT-PG 1091
Query: 935 QNECECKKGFRGNGI---DCEPITSC-----LEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
EC+C +G+ + +C I C L + G CH + G + C C G+
Sbjct: 1092 DFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCH-------NTEGSYRCECPPGH 1144
Query: 987 E 987
+
Sbjct: 1145 Q 1145
Score = 35.0 bits (79), Expect = 0.95
Identities = 64/286 (22%), Positives = 94/286 (32%), Gaps = 65/286 (22%)
Query: 1948 PRCCKGYFGRDCQACPGG---PDAPCNNRGVCLDQ-----------YSATGECKCNTGFN 1993
P C+ G CP G + C + C+++ + +C C GF+
Sbjct: 1986 PGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFS 2045
Query: 1994 ----GTACE-----MCWPGRFGPDCLPCGCSDHG--QCDDGITGSGQC-LCETGWTGPSC 2041
G C+ C+ G C +H +C + G G CE T P
Sbjct: 2046 LSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDE 2105
Query: 2042 DTQAVLP------------AVCTPPCSAHATCKEN---NT-----CECNLDYEGDGITCT 2081
+ + P AV C CK NT CEC Y G C
Sbjct: 2106 AFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILAGNECV 2165
Query: 2082 VVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK-GDGHSCTEIDPCADGLNGGCHEHAT 2140
D C N C C C+C++G++ G +C +I+ CA
Sbjct: 2166 DTDECSVGN-PCGN-GTCKNVIGGFECTCEEGFEPGPMMTCEDINECA-------QNPLL 2216
Query: 2141 CK---MTGPGKHKCECKSHYV--GDGLNCEPEQLPIDRCLQDNGQC 2181
C + G ++C+C YV D C+ E D C + C
Sbjct: 2217 CAFRCVNTYGSYECKCPVGYVLREDRRMCKDE----DECEEGKHDC 2258
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 123 bits (308), Expect = 3e-27
Identities = 83/264 (31%), Positives = 113/264 (42%), Gaps = 23/264 (8%)
Query: 1352 AQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPL 1411
+ N C G CL+ ++ + C C + G C + + I+ SC +G +
Sbjct: 137 SSNPCQNGGTCLN-LHDSFFCICPPQWKGPLC-SADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 1412 GDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN----------SDGTASCKCAAG 1461
G SC C G C A+ D+C G + A C+ + SC C AG
Sbjct: 195 GSYSCHCPPETYGPQC--ASKYDDCEGG--SVARCVHGICEDLMREQAGEPKYSCVCDAG 250
Query: 1462 --FQGNGTICTAI-NACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCL 1518
F N CT + C G CS C T C G+ G+G +C +IN C
Sbjct: 251 WMFSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECE 310
Query: 1519 ENHGGCD--KNAECTQTGPNQAACN-CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHT 1575
N+GGC EC T P + C C P Y GDG+VCTL ++C NGGC A C+ T
Sbjct: 311 INNGGCSVAPPVECVNT-PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSST 369
Query: 1576 GQVERTCTCKPNYIGDGFTCRGSI 1599
CTC P Y G+G+ G +
Sbjct: 370 LGSLPLCTCLPGYTGNGYGPNGCV 393
Score = 113 bits (283), Expect = 2e-24
Identities = 88/273 (32%), Positives = 119/273 (43%), Gaps = 29/273 (10%)
Query: 745 SNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHG-TCNNRI 803
SNPC G C + L + CIC ++G C +D N+ C +G TC N +
Sbjct: 138 SNPCQNGGTCLN-LHDSFFCICPPQWKGPLCS--ADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 804 DSDGACLTGTCRDGSAGRLCDKQTSAC-GPYVQFCHIHATCE------YSNGTASCICKA 856
S C + G C + C G V C +H CE SC+C A
Sbjct: 195 GSYSC----HCPPETYGPQCASKYDDCEGGSVARC-VHGICEDLMREQAGEPKYSCVCDA 249
Query: 857 G--YEGDGTLCS-EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINN 913
G + + C+ + D C+ PG CS +C T + C GW GNG C +IN
Sbjct: 250 GWMFSPNSPACTLDRDECS-FQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINE 308
Query: 914 CLLPSAGGCH--DNASCLYVGPGQNECE-CKKGFRGNGIDCEPITSCLEQTGKCHPLASC 970
C + + GGC C+ PG + C+ C G++G+G C C G CHP ASC
Sbjct: 309 CEINN-GGCSVAPPVECVNT-PGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASC 366
Query: 971 QSTSSGVWSCVCQEGYEGDGFLCYG-NAAVELS 1002
ST + C C GY G+G YG N V+LS
Sbjct: 367 SSTLGSLPLCTCLPGYTGNG---YGPNGCVQLS 396
Score = 97.8 bits (242), Expect = 1e-19
Identities = 79/268 (29%), Positives = 110/268 (41%), Gaps = 49/268 (18%)
Query: 101 CPGRW-GPDCI----ECPGGAGSP--CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADD 153
CP +W GP C EC +G+P C G+C M G+ +C C G C + DD
Sbjct: 158 CPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM-GSYSCHCPPETYGPQCASKYDD 216
Query: 154 NLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPS 213
G SV CVHG+C + YS CD + P + C+
Sbjct: 217 CEGG----SVARCVHGICEDLMREQAGEPKYSCV----CD-----AGWMFSPNSPACTLD 263
Query: 214 TEDENKLECKCLPNYRGDGKYCDPINPCLRKI-CHPHAHCTYLGPNRHSCTCQEGYRGDG 272
+ EC P PC + C Y G C G++G+G
Sbjct: 264 RD-----ECSFQPG------------PCSTLVQCFNTQGSFYCG------ACPTGWQGNG 300
Query: 273 QVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCE-CKEHYQNFVPGVGCSMTDICK-SDN 330
+C ++ C+IN G C V + PG SHC+ C YQ G C++TDIC S+
Sbjct: 301 YICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQG--DGRVCTLTDICSVSNG 358
Query: 331 PCHRNANCTTVAPGRTECICQKGYVGDG 358
CH +A+C++ C C GY G+G
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNG 386
Score = 85.9 bits (211), Expect = 5e-16
Identities = 72/271 (26%), Positives = 100/271 (36%), Gaps = 59/271 (21%)
Query: 1969 PCNNRGVCLDQYSA-----------------TGECKCNTGF-----NGTACE-------- 1998
PC N G CL+ + + EC+ +G NG C
Sbjct: 140 PCQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSC 199
Query: 1999 MCWPGRFGPDCLP--CGCSD-------HGQCDDGITGSG-----QCLCETGW----TGPS 2040
C P +GP C C HG C+D + C+C+ GW P+
Sbjct: 200 HCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFSPNSPA 259
Query: 2041 CDTQAVLPAVCTPPCSAHATCKENNTC----ECNLDYEGDGITCTVVDFCKQDNGGCA-- 2094
C + PCS C C ++G+G C ++ C+ +NGGC+
Sbjct: 260 CTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVA 319
Query: 2095 -KVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCEC 2153
V + G+ +C GY+GDG CT D C+ NGGCH A+C T C C
Sbjct: 320 PPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVS-NGGCHPDASCSSTLGSLPLCTC 378
Query: 2154 KSHYVGDGLNCEPEQLPIDRCLQD---NGQC 2181
Y G+G + CL NGQC
Sbjct: 379 LPGYTGNGYGPNGCVQLSNICLSHPCLNGQC 409
Score = 78.2 bits (191), Expect = 1e-13
Identities = 79/269 (29%), Positives = 106/269 (39%), Gaps = 54/269 (20%)
Query: 1948 PRCCKGYFGRDCQACPGGPDAPCNNRGVCLD-QYSATGE----CKCNTGF----NGTACE 1998
P+C Y C GG A C + G+C D GE C C+ G+ N AC
Sbjct: 208 PQCASKY-----DDCEGGSVARCVH-GICEDLMREQAGEPKYSCVCDAGWMFSPNSPACT 261
Query: 1999 MCWPGRFGPDCLPCGCSDHGQCDDGITGSGQC-LCETGWTGPSCDTQAVLPAVCT----- 2052
+ R P CS QC + GS C C TGW G + +
Sbjct: 262 L---DRDECSFQPGPCSTLVQCFN-TQGSFYCGACPTGWQGNGYICEDINECEINNGGCS 317
Query: 2053 --PPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK-GTKVSCS 2109
PP T ++ C Y+GDG CT+ D C NGGC A CS G+ C+
Sbjct: 318 VAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT 377
Query: 2110 CQKGYKGDGH---SCTEID------PCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
C GY G+G+ C ++ PC LNG C + + + C+C S +
Sbjct: 378 CLPGYTGNGYGPNGCVQLSNICLSHPC---LNGQCIDTVS-------GYFCKCDSGWT-- 425
Query: 2161 GLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
G+NC I+ CL + C CVD
Sbjct: 426 GVNCTEN---INECL--SNPCLNGGTCVD 449
Score = 65.1 bits (157), Expect = 9e-10
Identities = 83/338 (24%), Positives = 127/338 (37%), Gaps = 84/338 (24%)
Query: 675 GTCVSCSLVYWSRCPANSEPT--ALFTHRC-VYSGRFGSLKSGCARYCNATVKIPKCCKG 731
GTC++ ++ CP + + + C +YSG S ++G C
Sbjct: 145 GTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTMGSYSCHCPPE 204
Query: 732 FYGPDC----NQCPGGFSNPCSGNGQCADSLGGNG-----TCICEEGFQGSQCQFCSDPN 782
YGP C + C GG C +G C D + +C+C+ G+ S PN
Sbjct: 205 TYGPQCASKYDDCEGGSVARCV-HGICEDLMREQAGEPKYSCVCDAGWMFS-------PN 256
Query: 783 KYGPRCN---KKCLCVHGTCNNRI---DSDGACLTGTCRDGSAGR--LCDKQTSACGPYV 834
P C +C G C+ + ++ G+ G C G G +C+ + C
Sbjct: 257 S--PACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICE-DINECEINN 313
Query: 835 QFCHIHATCEYSNGTASCICKA---GYEGDGTLCSEMDPCT------------------- 872
C + E N S C+A GY+GDG +C+ D C+
Sbjct: 314 GGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSL 373
Query: 873 ------------GLTPGGCSR-----------NAECIKTGTGTHTCVCQQGWTGNGRDCS 909
G P GC + N +CI T +G + C C GWT G +C+
Sbjct: 374 PLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSG-YFCKCDSGWT--GVNCT 430
Query: 910 E-INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRG 946
E IN CL + C + +C+ G CEC + + G
Sbjct: 431 ENINECL---SNPCLNGGTCV-DGVDSFSCECTRLWTG 464
Score = 58.9 bits (141), Expect = 6e-08
Identities = 56/237 (23%), Positives = 85/237 (35%), Gaps = 64/237 (27%)
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGP-------SCDTQAVLPAVCT--------- 2052
C C + G C + + S C+C W GP C+ + P C
Sbjct: 136 CSSNPCQNGGTCLN-LHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTCVNTM 194
Query: 2053 -------------PPCSA--------------HATC-----------KENNTCECNLDYE 2074
P C++ H C K + C+ +
Sbjct: 195 GSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMREQAGEPKYSCVCDAGWMFS 254
Query: 2075 GDGITCTV-VDFCKQDNGGCAKVARC-SQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLN 2132
+ CT+ D C G C+ + +C + +G+ +C G++G+G+ C +I+ C N
Sbjct: 255 PNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEIN-N 313
Query: 2133 GGCHEHATCK-MTGPGKHKCE-CKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
GGC + + PG C+ C Y GDG C D C NG CH DA C
Sbjct: 314 GGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC----TLTDICSVSNGGCHPDASC 366
Score = 51.2 bits (121), Expect = 1e-05
Identities = 59/221 (26%), Positives = 75/221 (33%), Gaps = 39/221 (17%)
Query: 166 CVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPEC-----AALLCPENSRCSPSTEDENKL 220
C +G L C C + GP C + EC L C C
Sbjct: 141 CQNGGTCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQNGGTC---VNTMGSY 197
Query: 221 ECKCLPNYRGD---GKYCD----PINPCLRKICHPHAHCTYLGPNRHSCTCQEG--YRGD 271
C C P G KY D + C+ IC G ++SC C G + +
Sbjct: 198 SCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMR-EQAGEPKYSCVCDAGWMFSPN 256
Query: 272 GQVC-LPVDPCQINFGNCPTKSTVCKYDGPGQSHC-ECKEHYQNFVPGVGCSMTDICKSD 329
C L D C G C T V ++ G +C C +Q G G IC+
Sbjct: 257 SPACTLDRDECSFQPGPCST--LVQCFNTQGSFYCGACPTGWQ----GNGY----ICEDI 306
Query: 330 NPCHRNANCTTVAP--------GRTEC-ICQKGYVGDGLTC 361
N C N +VAP G + C C GY GDG C
Sbjct: 307 NECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDGRVC 347
Score = 43.9 bits (102), Expect = 0.002
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 20/118 (16%)
Query: 120 CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS----CSSVC---NCVHGVCN 172
C+ SC+ + C+C G+ G N +GP+ S++C C++G C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTG---------NGYGPNGCVQLSNICLSHPCLNGQCI 410
Query: 173 SGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG 230
+ G C+C S +TG C + I EC + C C + + C+C + G
Sbjct: 411 DTVSGY-FCKCDSGWTGVNCTENINECLSNPCLNGGTC---VDGVDSFSCECTRLWTG 464
Score = 42.4 bits (98), Expect = 0.006
Identities = 27/73 (36%), Positives = 34/73 (46%), Gaps = 8/73 (10%)
Query: 1969 PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSG 2028
PC N G C+D S CKC++G+ G C +CL C + G C DG+ S
Sbjct: 403 PCLN-GQCIDTVSGYF-CKCDSGWTGVNCT-----ENINECLSNPCLNGGTCVDGV-DSF 454
Query: 2029 QCLCETGWTGPSC 2041
C C WTG C
Sbjct: 455 SCECTRLWTGALC 467
Score = 41.2 bits (95), Expect = 0.013
Identities = 47/176 (26%), Positives = 63/176 (35%), Gaps = 33/176 (18%)
Query: 54 CPDGY-------TMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGR-- 104
CP GY T+ SV C + SLP C C PG
Sbjct: 336 CPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCT-----------CLPGYTG 384
Query: 105 --WGPD-CIECPGGAGS-PCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSC 160
+GP+ C++ S PC G C + + G C C G+ G C ++ L P
Sbjct: 385 NGYGPNGCVQLSNICLSHPCLN-GQCIDTVSGY-FCKCDSGWTGVNCTENINECLSNPCL 442
Query: 161 SSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTED 216
+ G C G+D +CEC +TG C P C L N S + D
Sbjct: 443 NG------GTCVDGVDSF-SCECTRLWTGALCQVPQQVCGESLSGINGSFSYRSPD 491
Score = 40.8 bits (94), Expect = 0.017
Identities = 39/145 (26%), Positives = 48/145 (33%), Gaps = 18/145 (12%)
Query: 1335 ECCAGFFGPQCQPCPGNAQN---VCFGNGICLDGVNGTGV-CECGEGFSGTACETCTEGK 1390
EC CQ CP Q VC IC G C TC G
Sbjct: 323 ECVNTPGSSHCQACPPGYQGDGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLPGY 382
Query: 1391 YG--------IHCDQAC---SCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
G + C C++G+C G C CD GW GV+C E N
Sbjct: 383 TGNGYGPNGCVQLSNICLSHPCLNGQCIDTVSGY-FCKCDSGWTGVNCTENINECLSN-P 440
Query: 1440 CHTSANCLTNSDGTASCKCAAGFQG 1464
C C+ D + SC+C + G
Sbjct: 441 CLNGGTCVDGVD-SFSCECTRLWTG 464
Score = 37.7 bits (86), Expect = 0.15
Identities = 34/117 (29%), Positives = 46/117 (39%), Gaps = 19/117 (16%)
Query: 1322 GCQP--KCVRTVITRECCA---GFFGPQCQPCPGNAQ--NVCFG----NGICLDGVNGTG 1370
GC P C T+ + C G+ G P G Q N+C NG C+D V+G
Sbjct: 359 GCHPDASCSSTLGSLPLCTCLPGYTGNGYGP-NGCVQLSNICLSHPCLNGQCIDTVSGY- 416
Query: 1371 VCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHC 1427
C+C G++G C C +CV G + SC+C W G C
Sbjct: 417 FCKCDSGWTGVNCTENINECLSNPCLNGGTCVDG------VDSFSCECTRLWTGALC 467
Score = 34.7 bits (78), Expect = 1.2
Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 8/54 (14%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ 776
KC G+ G +C N+C SNPC G C D + + +C C + G+ CQ
Sbjct: 419 KCDSGWTGVNCTENINEC---LSNPCLNGGTCVDGV-DSFSCECTRLWTGALCQ 468
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 120 bits (302), Expect = 1e-26
Identities = 100/344 (29%), Positives = 149/344 (43%), Gaps = 38/344 (11%)
Query: 663 HRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNAT 722
+ C + + G CV+ Y C + T C + GC C +
Sbjct: 1202 NECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATP-DRQGCTDIDECMIMNGGCDTQCTNS 1260
Query: 723 VKIPKC-CKGFY-----GPDCNQCPGGFSNP--CSGNGQCADSLGGNGTCICEEGFQGS- 773
+C C Y G C +NP C G GQC + + G C+C +GF S
Sbjct: 1261 EGSYECSCSEGYALMPDGRSCADIDECENNPDICDG-GQCTN-IPGEYRCLCYDGFMASM 1318
Query: 774 QCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGA-CLTG-TCRDGSAGRLCDKQTSACG 831
+ C D N+ N +C+ G C N S C G + + G+ G C C
Sbjct: 1319 DMKTCIDVNECDLNSN---ICMFGECENTKGSFICHCQLGYSVKKGTTG--C-TDVDECE 1372
Query: 832 PYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTG 891
C +HA+C G+ C C+ G+ G+G C ++D C+ T CS NA+C+ T G
Sbjct: 1373 IGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGT-HQCSINAQCVNT-PG 1430
Query: 892 THTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGI 949
++ C C +G+TG+G CS+++ C + C +N CL V PG CEC+ GF +
Sbjct: 1431 SYRCACSEGFTGDGFTCSDVDEC-AENINLC-ENGQCLNV-PGAYRCECEMGFTPASDSR 1487
Query: 950 DCEPITSCLEQT----GKCHPLASCQSTSSGVWSCVCQEGYEGD 989
C+ I C Q G C+ L G++ C+C +GYE D
Sbjct: 1488 SCQDIDECSFQNICVFGTCNNL-------PGMFHCICDDGYELD 1524
Score = 102 bits (253), Expect = 6e-21
Identities = 82/283 (28%), Positives = 119/283 (42%), Gaps = 29/283 (10%)
Query: 1322 GCQPKCVRTVITREC-CAGFFG--PQCQPCPG-----NAQNVCFGNGICLDGVNGTGVCE 1373
GC +C + + EC C+ + P + C N ++C G G C + + G C
Sbjct: 1252 GCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDG-GQCTN-IPGEYRCL 1309
Query: 1374 CGEGFSGTA-CETCTEGKYGIHCDQACS-CVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431
C +GF + +TC + CD + C+ G C + G C C +G+
Sbjct: 1310 CYDGFMASMDMKTCIDVN---ECDLNSNICMFGEC-ENTKGSFICHCQLGYSVKKGTTGC 1365
Query: 1432 TE-DNCN---GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKAD 1487
T+ D C C A+CL N G+ C C G+ GNG C ++ C CS A
Sbjct: 1366 TDVDECEIGAHNCDMHASCL-NIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQ 1424
Query: 1488 CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYT 1547
C T PG C C G+TGDG C +++ C EN C+ N +C P C C +T
Sbjct: 1425 CVNT-PGSYRCACSEGFTGDGFTCSDVDECAENINLCE-NGQCLNV-PGAYRCECEMGFT 1481
Query: 1548 --GDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
D + C I+ C +N F CN+ + C C Y
Sbjct: 1482 PASDSRSCQDIDECSFQN--ICVFGTCNNLPGMFH-CICDDGY 1521
Score = 94.0 bits (232), Expect = 2e-18
Identities = 87/321 (27%), Positives = 131/321 (40%), Gaps = 39/321 (12%)
Query: 1270 NRCDNNDTTIIRGRCRTC--SSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQP-K 1326
+ C+ N G C S + CP G + L + C+ + L C+ K
Sbjct: 1160 DECERNPLLCRGGTCVNTEGSFQCDCPLGHE-LSPSREDCVDINECSLSDNL---CRNGK 1215
Query: 1327 CVRTVITRECCA--GFFG-PQCQPCPGNAQNVCFGNGICLDGVNGTGV--CECGEGFS-- 1379
CV + T +C G+ P Q C + + G N G C C EG++
Sbjct: 1216 CVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALM 1275
Query: 1380 --GTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN 1437
G +C E + + C G+C P G+ C C G+ D T D
Sbjct: 1276 PDGRSCADIDECE-----NNPDICDGGQCTNIP-GEYRCLCYDGFMA-SMDMKTCIDV-- 1326
Query: 1438 GTCHTSAN-CL----TNSDGTASCKCAAGF--QGNGTICTAINACEISNGGCSAKADCKR 1490
C ++N C+ N+ G+ C C G+ + T CT ++ CEI C A C
Sbjct: 1327 NECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN 1386
Query: 1491 TTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDG 1550
PG C+C+ G+ G+GI C++++ C C NA+C T P C C +TGDG
Sbjct: 1387 I-PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNT-PGSYRCACSEGFTGDG 1444
Query: 1551 KVCTLINVC-----LTKNGGC 1566
C+ ++ C L +NG C
Sbjct: 1445 FTCSDVDECAENINLCENGQC 1465
Score = 88.2 bits (217), Expect = 9e-17
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 27/256 (10%)
Query: 1352 AQNVCFGNGICLDGVNGTGVCECGEGFSGTAC-ETCTEGKYGIHCDQACSCVHGRCN-QG 1409
+ N+C NG C++ + GT C C G+ T + CT+ C ++G C+ Q
Sbjct: 1207 SDNLC-RNGKCVNMI-GTYQCSCNPGYQATPDRQGCTD-------IDECMIMNGGCDTQC 1257
Query: 1410 PLGDGS--CDCDVGWR----GVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
+GS C C G+ G C + +N C C TN G C C GF
Sbjct: 1258 TNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICD-GGQC-TNIPGEYRCLCYDGFM 1315
Query: 1464 GNGTI--CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLE 1519
+ + C +N C++++ C +C+ T G +C C+ GY+ C +++ C
Sbjct: 1316 ASMDMKTCIDVNECDLNSNICMF-GECENTK-GSFICHCQLGYSVKKGTTGCTDVDECEI 1373
Query: 1520 NHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVE 1579
CD +A C P C+C + G+G C ++ C CS A C +T
Sbjct: 1374 GAHNCDMHASCLNI-PGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSY 1432
Query: 1580 RTCTCKPNYIGDGFTC 1595
R C C + GDGFTC
Sbjct: 1433 R-CACSEGFTGDGFTC 1447
Score = 85.9 bits (211), Expect = 5e-16
Identities = 75/261 (28%), Positives = 98/261 (37%), Gaps = 26/261 (9%)
Query: 103 GRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTA-CETCADDNLFGPSCS 161
GR D EC C+G G C + G C C +GF + +TC D N C
Sbjct: 1278 GRSCADIDECENNPDI-CDG-GQCTN-IPGEYRCLCYDGFMASMDMKTCIDVN----ECD 1330
Query: 162 SVCN-CVHGVCNSGLDGDGTCEC---YSAYTGPKCDKPIPEC--AALLCPENSRCSPSTE 215
N C+ G C + G C C YS G + EC A C ++ C
Sbjct: 1331 LNSNICMFGECEN-TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC---LN 1386
Query: 216 DENKLECKCLPNYRGDGKYCDPINPCLRKI--CHPHAHCTYLGPNRHSCTCQEGYRGDGQ 273
+C C + G+G C ++ C C +A C P + C C EG+ GDG
Sbjct: 1387 IPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNT-PGSYRCACSEGFTGDGF 1445
Query: 274 VCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCH 333
C VD C N C + + PG CEC+ + C D C N C
Sbjct: 1446 TCSDVDECAENINLCENGQCL---NVPGAYRCECEMGFTPASDSRSCQDIDECSFQNIC- 1501
Query: 334 RNANCTTVAPGRTECICQKGY 354
C + PG CIC GY
Sbjct: 1502 VFGTCNNL-PGMFHCICDDGY 1521
Score = 82.8 bits (203), Expect = 4e-15
Identities = 67/235 (28%), Positives = 96/235 (40%), Gaps = 27/235 (11%)
Query: 1967 DAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGIT- 2025
D C N G C++ T +C CN G+ T P R G + +G CD T
Sbjct: 1208 DNLCRN-GKCVNMIG-TYQCSCNPGYQAT------PDRQGCTDIDECMIMNGGCDTQCTN 1259
Query: 2026 --GSGQCLCETGWT----GPSC---DTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGD 2076
GS +C C G+ G SC D P +C + + C D
Sbjct: 1260 SEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMD 1319
Query: 2077 GITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY--KGDGHSCTEIDPCADGLNGG 2134
TC V+ C ++ C C C CQ GY K CT++D C G +
Sbjct: 1320 MKTCIDVNECDLNSNICM-FGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHN- 1377
Query: 2135 CHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
C HA+C + PG KC C+ ++G+G+ C + +D C QC +A+CV+
Sbjct: 1378 CDMHASC-LNIPGSFKCSCREGWIGNGIKC----IDLDECSNGTHQCSINAQCVN 1427
Score = 82.8 bits (203), Expect = 4e-15
Identities = 67/253 (26%), Positives = 106/253 (41%), Gaps = 45/253 (17%)
Query: 1950 CCKGYF----GRDC---QACPGGPD----APCNN-----RGVCLDQYSATGECKCNTGFN 1993
C +GY GR C C PD C N R +C D + A+ + K T +
Sbjct: 1268 CSEGYALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMK--TCID 1325
Query: 1994 GTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWT---GPSCDTQAVLPAV 2050
C+ L G+C++ GS C C+ G++ G + T +
Sbjct: 1326 VNECD-----------LNSNICMFGECEN-TKGSFICHCQLGYSVKKGTTGCTDVDECEI 1373
Query: 2051 CTPPCSAHATCKE---NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVS 2107
C HA+C + C C + G+GI C +D C C+ A+C
Sbjct: 1374 GAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYR 1433
Query: 2108 CSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHY--VGDGLNCE 2165
C+C +G+ GDG +C+++D CA+ +N E+ C + PG ++CEC+ + D +C+
Sbjct: 1434 CACSEGFTGDGFTCSDVDECAENIN--LCENGQC-LNVPGAYRCECEMGFTPASDSRSCQ 1490
Query: 2166 PEQLPIDRCLQDN 2178
ID C N
Sbjct: 1491 ----DIDECSFQN 1499
Score = 81.3 bits (199), Expect = 1e-14
Identities = 95/368 (25%), Positives = 123/368 (33%), Gaps = 84/368 (22%)
Query: 53 KCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCC---PGRWGPDC 109
+CP+G T+ +G V + D R E C H + CC WG +C
Sbjct: 981 ECPEGLTLDGTGRVCL-DIR--MEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC 1037
Query: 110 IECP-----------------GGAGSPCNGR-------------GSCAEG----MEGNGT 135
ECP G GR G C G G+
Sbjct: 1038 EECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFK 1097
Query: 136 CSCQEGFGGTACE-TCADDNLFGPSCSSVCNCVHGVCNSGL----DGDGTCECYSAYTG- 189
C C GF E C D C +C SG+ G CEC+ Y
Sbjct: 1098 CRCNSGFALDMEERNCTD--------IDECRISPDLCGSGICVNTPGSFECECFEGYESG 1149
Query: 190 ---PKCDKPIPECA--ALLCPENSRCSPSTEDENKLECKC-----LPNYRGDGKYCDPIN 239
K I EC LLC R E +C C L R D C IN
Sbjct: 1150 FMMMKNCMDIDECERNPLLC----RGGTCVNTEGSFQCDCPLGHELSPSRED---CVDIN 1202
Query: 240 PC--LRKICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCLPVDPCQINFGNCPTKSTVC 295
C +C +G + C+C GY+ D Q C +D C I G C T+ T
Sbjct: 1203 ECSLSDNLCRNGKCVNMIG--TYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCT-- 1258
Query: 296 KYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV 355
+ G C C E Y G C+ D C+++ CT + PG C+C G++
Sbjct: 1259 --NSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCTNI-PGEYRCLCYDGFM 1315
Query: 356 G--DGLTC 361
D TC
Sbjct: 1316 ASMDMKTC 1323
Score = 79.3 bits (194), Expect = 4e-14
Identities = 89/348 (25%), Positives = 129/348 (37%), Gaps = 59/348 (16%)
Query: 1267 IQKNRCDNNDTTIIRGRCRTCSS--ELTCPFGTKSLGNEKRRCI-------YTSYFMGRR 1317
I N CD + + G C + CP G L + RRC +T++ G+
Sbjct: 2055 IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFV-LSDNGRRCFDTRQSFCFTNFENGKC 2113
Query: 1318 TLFIGCQPKCVRTVITRECCAGF----FGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCE 1373
++ PK T + CC+ +G C+ CP + D V +C
Sbjct: 2114 SV-----PKAFNTTKAKCCCSKMPGEGWGDPCELCPKD------------DEVAFQDLCP 2156
Query: 1374 CGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWR----GVHC-- 1427
G G + +T + + CS +G+C G C+C +G+ GV C
Sbjct: 2157 YGHGTVPSLHDTREDVNECLESPGICS--NGQCINTD-GSFRCECPMGYNLDYTGVRCVD 2213
Query: 1428 -DNATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGFQ-GNGTICTAINACEISNGGCSA 1484
D + + C NGTC TN G+ C C GF+ G C IN C + C+
Sbjct: 2214 TDECSIGNPCGNGTC-------TNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAF 2266
Query: 1485 KADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 1542
+ T G CTC GY D +C +++ C E C+ + C C
Sbjct: 2267 RC---MNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCIC 2323
Query: 1543 LP--AYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
P A DG+ C N C TK G C N G C C +
Sbjct: 2324 PPGMARRPDGEGCVDENECRTKPGICENGRCVNIIGSYR--CECNEGF 2369
Score = 79.0 bits (193), Expect = 6e-14
Identities = 80/306 (26%), Positives = 113/306 (36%), Gaps = 65/306 (21%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFG-GTACETCADDNLFGPSCSSVCN- 165
+C++ +P RG EG+ C C G + E C D N CS N
Sbjct: 1155 NCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDIN----ECSLSDNL 1210
Query: 166 CVHGVCNSGLDGDGTCEC---YSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLEC 222
C +G C + + G C C Y A + I EC + +++C T E EC
Sbjct: 1211 CRNGKCVNMI-GTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQC---TNSEGSYEC 1266
Query: 223 KCLPNYR--GDGKYCDPINPCLRK--ICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCL 276
C Y DG+ C I+ C IC CT + P + C C +G+ D + C+
Sbjct: 1267 SCSEGYALMPDGRSCADIDECENNPDICDG-GQCTNI-PGEYRCLCYDGFMASMDMKTCI 1324
Query: 277 PVDPCQIN-----FGNCPTK--STVCK--------------------------------- 296
V+ C +N FG C S +C
Sbjct: 1325 DVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASC 1384
Query: 297 YDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGYV 355
+ PG C C+E + G+ C D C + + C NA C PG C C +G+
Sbjct: 1385 LNIPGSFKCSCREGWIG--NGIKCIDLDECSNGTHQCSINAQCVNT-PGSYRCACSEGFT 1441
Query: 356 GDGLTC 361
GDG TC
Sbjct: 1442 GDGFTC 1447
Score = 76.6 bits (187), Expect = 3e-13
Identities = 72/268 (26%), Positives = 103/268 (38%), Gaps = 54/268 (20%)
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT----ACETCTEGKYGIH-CDQA 1398
+C+ PG +C NG+C++ + G+ CEC GFS CE E G + C +
Sbjct: 1811 ECKEIPG----IC-ANGVCINQI-GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRN 1864
Query: 1399 CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCL----------- 1447
C++ G C+C G++ + NG C CL
Sbjct: 1865 ADCINSP------GSYRCECAAGFKL----------SPNGACVDRNECLEIPNVCSHGLC 1908
Query: 1448 TNSDGTASCKCAAGFQGNG--TICTAINACE---ISNGGCSAKADCKRTTPGRRVCTCKA 1502
+ G+ C C GF+ + T+C ++ CE NG C + T G C C
Sbjct: 1909 VDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTC-------KNTVGSYNCLCYP 1961
Query: 1503 GYT-GDGIVCLEINPCLENHGGCDKNAEC-TQTGPNQAACNCLPAYTGDGKVCTLINVCL 1560
G+ CL+I+ C G +N C + G + CN T DGK C N C+
Sbjct: 1962 GFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECV 2021
Query: 1561 TKNGGCSEFAICNHTGQVERTCTCKPNY 1588
G CS N G C C P Y
Sbjct: 2022 ALPGSCSPGTCQNLEGSFR--CICPPGY 2047
Score = 75.5 bits (184), Expect = 6e-13
Identities = 64/243 (26%), Positives = 92/243 (37%), Gaps = 39/243 (16%)
Query: 124 GSCAEGMEGNGTCSCQEGF----GGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDG 179
G C E +G+ C CQ G+ G T C + + +C +C++ + G
Sbjct: 1339 GEC-ENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLN------IPGSF 1391
Query: 180 TCECYSAYTGP--KCDKPIPECA--ALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYC 235
C C + G KC + EC+ C N++C C C + GDG C
Sbjct: 1392 KCSCREGWIGNGIKCID-LDECSNGTHQCSINAQC---VNTPGSYRCACSEGFTGDGFTC 1447
Query: 236 DPINPCLRKI--CHPHAHCTYLGPNRHSCTCQEGYR--GDGQVCLPVDPCQIN----FGN 287
++ C I C + C + P + C C+ G+ D + C +D C FG
Sbjct: 1448 SDVDECAENINLCE-NGQCLNV-PGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGT 1505
Query: 288 CPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTE 347
C PG HC C + Y+ G C+ D C C N C PGR E
Sbjct: 1506 CNNL--------PGMFHCICDDGYELDRTGGNCTDIDECADPINC-VNGLCVN-TPGRYE 1555
Query: 348 CIC 350
C C
Sbjct: 1556 CNC 1558
Score = 74.3 bits (181), Expect = 1e-12
Identities = 96/367 (26%), Positives = 133/367 (36%), Gaps = 69/367 (18%)
Query: 1272 CDNNDTTIIRG--RCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQ-PKCV 1328
C+N I G RC + GT+ L N + C L CQ
Sbjct: 2349 CENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCF-------AEVLQTICQMASSS 2401
Query: 1329 RTVITRE--CCAGF--FGPQCQPCP--GNAQ-------------------------NVCF 1357
R ++T+ CC G +G QC+ CP G AQ N+C
Sbjct: 2402 RNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCT 2461
Query: 1358 GNGICLDGVNGTGVCECGEGF----SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGD 1413
NG C++ + G+ C C G+ SGT+C E C Q+ + C G
Sbjct: 2462 -NGQCINTM-GSFRCFCKVGYTTDISGTSCIDLDE------CSQSPKPCNYICKNTE-GS 2512
Query: 1414 GSCDCDVGWRGVHCDNATTED--NCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTA 1471
C C G+ + D T +D C H N+ G +CKC GF + T C
Sbjct: 2513 YQCSCPRGYV-LQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACID 2571
Query: 1472 INACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD--GIVCLEINPCLENHGGCDKNAE 1529
N C C AK C + TPG C C+ G++ D G+ C +++ C NH C +
Sbjct: 2572 NNECGSQPSLCGAKGIC-QNTPGSFSCECQRGFSLDATGLNCEDVDECDGNH-RCQHGCQ 2629
Query: 1530 CTQTGPNQAACNCLPAYTG--DGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPN 1587
G C C Y C N C N C + N G + C C
Sbjct: 2630 NILGG---YRCGCPQGYIQHYQWNQCVDENECSNPN-ACGSASCYNTLGSYK--CACPSG 2683
Query: 1588 YIGDGFT 1594
+ D F+
Sbjct: 2684 FSFDQFS 2690
Score = 73.9 bits (180), Expect = 2e-12
Identities = 75/287 (26%), Positives = 105/287 (36%), Gaps = 67/287 (23%)
Query: 731 GFYGPDCNQCPGGFSNPCSGNGQCADSLGG----------------------NGTCICEE 768
G Y +CN+ GF + SG +C D+ G C C+
Sbjct: 2359 GSYRCECNE---GFQSSSSGT-ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDG 2414
Query: 769 GFQ-GSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT 827
G G QC+ C P K +C HG G DG C
Sbjct: 2415 GRGWGHQCELCPLPGT----AQYKKICPHGP-------------GYTTDGRDIDECKVMP 2457
Query: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEGD--GTLCSEMDPCTGLTPGGCSRNAEC 885
+ C + C + G+ C CK GY D GT C ++D C+ +P C N C
Sbjct: 2458 NLC--------TNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQ-SPKPC--NYIC 2506
Query: 886 IKTGTGTHTCVCQQGWT--GNGRDCSEINNCLLPSAGGCHDNASCLYVGP-GQNECECKK 942
K G++ C C +G+ +G+ C +++ C N L V G C+C
Sbjct: 2507 -KNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTKQ-----HNCQFLCVNTLGGFTCKCPP 2560
Query: 943 GFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
GF + C C Q C CQ+T G +SC CQ G+ D
Sbjct: 2561 GFTQHHTACIDNNECGSQPSLCGAKGICQNTP-GSFSCECQRGFSLD 2606
Score = 73.6 bits (179), Expect = 2e-12
Identities = 77/257 (29%), Positives = 104/257 (40%), Gaps = 27/257 (10%)
Query: 1347 PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRC 1406
P PG GNG GV G GV G+G T T I A C++GRC
Sbjct: 460 PIPG-------GNGFS-PGVGGAGVGAGGQGPIITGL-TILNQTIDICKHHANLCLNGRC 510
Query: 1407 NQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNG 1466
+ C+C++G++ + D C T+ +C+ N+ G+ CKC AGFQ
Sbjct: 511 IP-TVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDCV-NTPGSYYCKCHAGFQRTP 568
Query: 1467 T--ICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINPCLENHG 1522
T C I+ C I NG C T G C C AG+ T DG C++ + C +
Sbjct: 569 TKQACIDIDEC-IQNGVLCKNGRCV-NTDGSFQCICNAGFELTTDGKNCVDHDECTTTN- 625
Query: 1523 GCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVER 1580
N C C C P + +G+ CT ++ C T G C N G
Sbjct: 626 -MCLNGMCINE-DGSFKCICKPGFVLAPNGRYCTDVDECQTP-GICMNGHCINSEGSFR- 681
Query: 1581 TCTCKPNY-IG-DGFTC 1595
C C P +G DG C
Sbjct: 682 -CDCPPGLAVGMDGRVC 697
Score = 72.8 bits (177), Expect = 4e-12
Identities = 76/267 (28%), Positives = 111/267 (41%), Gaps = 32/267 (11%)
Query: 1335 ECCAGFFGPQCQPCPGNAQ-----NVCFGNGICLDGVNGTGVCECGEGFSGTACET-CTE 1388
EC AGF C + NVC +G+C+D + G+ C C GF + +T C +
Sbjct: 1877 ECAAGFKLSPNGACVDRNECLEIPNVC-SHGLCVD-LQGSYQCICHNGFKASQDQTMCMD 1934
Query: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN---GTCHTSAN 1445
C++ C +G C + +G +C C G+ H ++ D C+ G +
Sbjct: 1935 VD---ECERH-PCGNGTC-KNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGR 1989
Query: 1446 CLTNSDGTASCKCAAGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAG 1503
C N G+ C C G++ +G C N C G CS C+ R C C G
Sbjct: 1990 CF-NEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP-GTCQNLEGSFR-CICPPG 2046
Query: 1504 YTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVC--TLINVC 1559
Y C++IN C E+ C CT T P C C P + + +G+ C T + C
Sbjct: 2047 YEVKSENCIDINECDEDPNIC-LFGSCTNT-PGGFQCLCPPGFVLSDNGRRCFDTRQSFC 2104
Query: 1560 LT--KNGGCSEFAICNHTGQVERTCTC 1584
T +NG CS N T + C C
Sbjct: 2105 FTNFENGKCSVPKAFNTT---KAKCCC 2128
Score = 69.3 bits (168), Expect = 5e-11
Identities = 64/232 (27%), Positives = 89/232 (38%), Gaps = 22/232 (9%)
Query: 1958 DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCL--PCGCS 2015
D C G D C C++ + C+C GF + C +CL P CS
Sbjct: 1850 DIDECSNG-DNLCQRNADCINS-PGSYRCECAAGFKLSPNGACVDRN---ECLEIPNVCS 1904
Query: 2016 DHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEG 2075
HG C D + GS QC+C G+ T + C + TCK L Y G
Sbjct: 1905 -HGLCVD-LQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKNTVGSYNCLCYPG 1962
Query: 2076 DGIT----CTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCAD 2129
+T C +D C G + RC + C C +GY+ DG +C + + C
Sbjct: 1963 FELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECV- 2021
Query: 2130 GLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
L G C TC+ G +C C Y NC + I+ C +D C
Sbjct: 2022 ALPGSC-SPGTCQNL-EGSFRCICPPGYEVKSENC----IDINECDEDPNIC 2067
Score = 69.3 bits (168), Expect = 5e-11
Identities = 89/367 (24%), Positives = 124/367 (33%), Gaps = 84/367 (22%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECP 113
CP GY + + + + +C +IC L C G C+ CP
Sbjct: 2043 CPPGYEVKSENCIDINECDED-------------PNIC----LFGSCTNTPGGFQCL-CP 2084
Query: 114 GGAGSPCNGR-------GSCAEGMEGNGTCSCQEGFG----------------GTACETC 150
G NGR C E NG CS + F G CE C
Sbjct: 2085 PGFVLSDNGRRCFDTRQSFCFTNFE-NGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELC 2143
Query: 151 ADDN--LFGPSC--------------SSVCNCVH--GVCNSG----LDGDGTCECYSAY- 187
D+ F C V C+ G+C++G DG CEC Y
Sbjct: 2144 PKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYN 2203
Query: 188 ---TGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYR-GDGKYCDPINPCLR 243
TG +C EC+ N C T EC C + G C+ IN C +
Sbjct: 2204 LDYTGVRC-VDTDECSIGNPCGNGTC---TNVIGSFECNCNEGFEPGPMMNCEDINECAQ 2259
Query: 244 K--ICHPHAHCTYLGPNRHSCTCQEGY--RGDGQVCLPVDPCQINFGNCPTKSTVCKYDG 299
+C T+ + CTC GY R D ++C +D C +C ++ +CK +
Sbjct: 2260 NPLLCAFRCMNTF---GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCK-NL 2315
Query: 300 PGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY--VGD 357
G C C G GC + C++ N C + G C C +G+
Sbjct: 2316 IGTFMCICPPGMARRPDGEGCVDENECRTKPGICENGRCVNII-GSYRCECNEGFQSSSS 2374
Query: 358 GLTCYGN 364
G C N
Sbjct: 2375 GTECLDN 2381
Score = 68.9 bits (167), Expect = 6e-11
Identities = 95/368 (25%), Positives = 130/368 (35%), Gaps = 63/368 (17%)
Query: 22 AETTGQARRCDRKSLLTIRTECRSCALNLG---VKCPDGYTMITSGSVGVRD----CRYT 74
+ETT + D S++ E C+ +G CP GY T GS + C
Sbjct: 310 SETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG 369
Query: 75 FEVRTYSLSLPGCRHICRKDYLQPRCCPGR-WG----PD-------------CIE----- 111
+ LPG R +Q C PGR WG P+ C++
Sbjct: 370 LVNGRCAQELPG-----RMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMG 424
Query: 112 -CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGV 170
PG AGS G G GNG G GGT N F P GV
Sbjct: 425 GIPGSAGSRPGGTGGNGFAPSGNGN---GYGPGGTGFIPIPGGNGFSP----------GV 471
Query: 171 CNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG 230
+G+ G + T I + A LC N RC P+ + C+C Y+
Sbjct: 472 GGAGVGAGGQGPIITGLTILNQTIDICKHHANLCL-NGRCIPTV---SSYRCECNMGYKQ 527
Query: 231 DGKY-CDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDG--QVCLPVDPCQINFGN 287
D C ++ C C + C P + C C G++ Q C+ +D C N
Sbjct: 528 DANGDCIDVDECTSNPC-TNGDCVNT-PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVL 585
Query: 288 CPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTE 347
C V + G C C ++ G C D C + N C N C G +
Sbjct: 586 CKNGRCV---NTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMC-LNGMCIN-EDGSFK 640
Query: 348 CICQKGYV 355
CIC+ G+V
Sbjct: 641 CICKPGFV 648
Score = 68.2 bits (165), Expect = 1e-10
Identities = 73/298 (24%), Positives = 111/298 (37%), Gaps = 64/298 (21%)
Query: 734 GPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGF----QGSQCQFCSDPNKYGPRCN 789
G D ++C N C+ NGQC +++G + C C+ G+ G+ C + ++ CN
Sbjct: 2447 GRDIDECKV-MPNLCT-NGQCINTMG-SFRCFCKVGYTTDISGTSCIDLDECSQSPKPCN 2503
Query: 790 KKCLCVHGTCNNR------IDSDGACLTGTCRD----------------GSAGRLCDK-- 825
C G+ + DG TC+D + G K
Sbjct: 2504 YICKNTEGSYQCSCPRGYVLQEDGK----TCKDLDECQTKQHNCQFLCVNTLGGFTCKCP 2559
Query: 826 -----------QTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGD--GTLCSEMDPCT 872
+ CG C C+ + G+ SC C+ G+ D G C ++D C
Sbjct: 2560 PGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECD 2619
Query: 873 GLTPGGCSRNAECIKTGTGTHTCVCQQGWTGN--GRDCSEINNCLLPSAGGCHDNASCLY 930
G C + I G + C C QG+ + C + N C P+A G +ASC Y
Sbjct: 2620 G--NHRCQHGCQNI---LGGYRCGCPQGYIQHYQWNQCVDENECSNPNACG---SASC-Y 2670
Query: 931 VGPGQNECECKKGFRGNGID--CEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
G +C C GF + C + C C+ C +T G + C C GY
Sbjct: 2671 NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCN--YGCSNTEGG-YLCGCPPGY 2725
Score = 66.6 bits (161), Expect = 3e-10
Identities = 83/317 (26%), Positives = 112/317 (35%), Gaps = 67/317 (21%)
Query: 1902 CGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDC-- 1959
CGS ++ CP W G Q C+ +P RN C + + C G C
Sbjct: 89 CGSRFHSYCCPGWKTLPGGNQ-CI--VPICRN--SCGDGFCSRPNMCTCSSGQISSTCGS 143
Query: 1960 ---QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSD 2016
Q C C N G C D + C+C G+ GT C G GC +
Sbjct: 144 KSIQQC----SVRCMNGGTCADDH-----CQCQKGYIGTYC--------GQPVCENGCQN 186
Query: 2017 HGQCDDGITGSGQCLCETGWTGPSCD---------TQA--------VLPAVCTPP-CSAH 2058
G+C G +C C G+TGP C+ TQ + VCT C A
Sbjct: 187 GGRC----IGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCAT 242
Query: 2059 ATCKENNTCE--------CNLDYEGDGIT--CTVVDFCKQDNGGCAKVARCSQKGTKVSC 2108
+ CE C + + T C VD C+ G C + C C
Sbjct: 243 IGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFEC 301
Query: 2109 SCQKGYKGD--GHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYV--GDGLNC 2164
C G+K C +ID C+ + G E C T G + C C YV DG C
Sbjct: 302 RCPAGHKQSETTQKCEDIDECS--IIPGICETGECSNT-VGSYFCVCPRGYVTSTDGSRC 358
Query: 2165 EPEQLPIDRCLQDNGQC 2181
++ + NG+C
Sbjct: 359 IDQRTGMCFSGLVNGRC 375
Score = 66.2 bits (160), Expect = 4e-10
Identities = 87/323 (26%), Positives = 120/323 (37%), Gaps = 73/323 (22%)
Query: 1293 CPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPK-CVR----TVITRECCAGF----FGP 1343
CP G ++G + R C+ T R T + G + CVR V ECC FG
Sbjct: 684 CPPGL-AVGMDGRVCVDTHM---RSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGE 739
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGT------------------GVCECGEGFSGTAC-- 1383
CQPCP A+N +G+C GV T G+CE G C
Sbjct: 740 PCQPCP--AKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICENLRGSYRCNCNS 797
Query: 1384 --ETCTEGKYGIHCDQA----CSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTED--N 1435
E G+ I D+ C +G C P G SC C G+ + T ED
Sbjct: 798 GYEPDASGRNCIDIDECLVNRLLCDNGLCRNTP-GSYSCTCPPGY-VFRTETETCEDINE 855
Query: 1436 CNGTCHTSANCLTNSDGTASCKCAAG--FQGNGTIC-----------TAINACEISNGGC 1482
C + C N+ G+ +C+C+ G G IC + CE++ G
Sbjct: 856 CESNPCVNGAC-RNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGA 914
Query: 1483 SAKADCKRT------TPGRRV---CTCKAGYTG-DGIVCLEINPCLENHGGCDKNAECTQ 1532
+ K++C T +P R C G G+ C ++N C G C N C
Sbjct: 915 TLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVC-PNGRCVN 973
Query: 1533 TGPNQAACNCLPAYT--GDGKVC 1553
+ C C T G G+VC
Sbjct: 974 S-KGSFHCECPEGLTLDGTGRVC 995
Score = 66.2 bits (160), Expect = 4e-10
Identities = 84/358 (23%), Positives = 131/358 (36%), Gaps = 67/358 (18%)
Query: 26 GQARRCDRKSLLTIRTECRS---------CALNLG---VKCPDGYTMITSGSVGVRDCR- 72
G ARR D + + ECR+ C +G +C +G+ +SG+ + + +
Sbjct: 2326 GMARRPDGEGCVD-ENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQG 2384
Query: 73 --YTFEVRTYSLSLPGCRHICRKDYLQPRCCPGR--WGPDCIECPGGAGSPCNGRGSCAE 128
+ ++T R++ K CC G WG C CP
Sbjct: 2385 LCFAEVLQTICQMASSSRNLVTKSEC---CCDGGRGWGHQCELCP--------------- 2426
Query: 129 GMEGNGTCS--CQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSA 186
+ G C G G T D+ P+ C +G C + + G C C
Sbjct: 2427 -LPGTAQYKKICPHGPGYTTDGRDIDECKVMPNL-----CTNGQCINTM-GSFRCFCKVG 2479
Query: 187 YT----GPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNY--RGDGKYCDPINP 240
YT G C + EC+ P N C + E +C C Y + DGK C ++
Sbjct: 2480 YTTDISGTSCID-LDECSQSPKPCNYICKNT---EGSYQCSCPRGYVLQEDGKTCKDLDE 2535
Query: 241 CLRKICHPHAHCTYLGPNR---HSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKY 297
C K +C +L N +C C G+ C+ + C C K +C+
Sbjct: 2536 CQTK----QHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKG-ICQ- 2589
Query: 298 DGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV 355
+ PG CEC+ + G+ C D C ++ C C + G C C +GY+
Sbjct: 2590 NTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQH--GCQNIL-GGYRCGCPQGYI 2644
Score = 65.9 bits (159), Expect = 5e-10
Identities = 86/320 (26%), Positives = 128/320 (40%), Gaps = 76/320 (23%)
Query: 719 CNATVKIPKC-CKGFYGPDCN-------QCPGGFSNPCSGNGQCADSLGGNGTCICEEGF 770
C TV +C C Y D N +C SNPC+ NG C ++ G+ C C GF
Sbjct: 510 CIPTVSSYRCECNMGYKQDANGDCIDVDECT---SNPCT-NGDCVNT-PGSYYCKCHAGF 564
Query: 771 QGSQC-QFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDG----SAGRLC-- 823
Q + Q C D ++ LC +G C N D C+ C G + G+ C
Sbjct: 565 QRTPTKQACIDIDEC---IQNGVLCKNGRCVNT-DGSFQCI---CNAGFELTTDGKNCVD 617
Query: 824 -DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY--EGDGTLCSEMDPCTGLTPGGCS 880
D+ T+ C ++ C +G+ CICK G+ +G C+++D C TPG C
Sbjct: 618 HDECTTT-----NMC-LNGMCINEDGSFKCICKPGFVLAPNGRYCTDVDECQ--TPGICM 669
Query: 881 RNAECIKTGTGTHTCVCQQGWTG--NGRDCSEINNCLLPSAGGCHDNASCLYVGPG---Q 935
N CI + G+ C C G +GR C ++ + + G C+ PG +
Sbjct: 670 -NGHCINS-EGSFRCDCPPGLAVGMDGRVC--VDTHMRSTCYGGIKKGVCVRPFPGAVTK 725
Query: 936 NECECKKGFRGNGIDCEPITSCLEQTGKCHPLAS-------------------------- 969
+EC C G G C+P + + + + H L S
Sbjct: 726 SECCCANPDYGFGEPCQPCPA--KNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI 783
Query: 970 CQSTSSGVWSCVCQEGYEGD 989
C++ G + C C GYE D
Sbjct: 784 CENLR-GSYRCNCNSGYEPD 802
Score = 65.9 bits (159), Expect = 5e-10
Identities = 59/211 (27%), Positives = 92/211 (43%), Gaps = 29/211 (13%)
Query: 1401 CVHGRCNQGPLGDGSCDCDVGWR-GVHCDNATTEDNCNGTCHTSANCL-TNSDGTASCKC 1458
C +G+C + +G C C+ G+ + N T D C + + + N+ G+ C+C
Sbjct: 1084 CTYGKC-RNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECEC 1142
Query: 1459 AAGFQGNGTI---CTAINACE----ISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGI 1509
G++ + C I+ CE + GG T G C C G+ +
Sbjct: 1143 FEGYESGFMMMKNCMDIDECERNPLLCRGGTCVN------TEGSFQCDCPLGHELSPSRE 1196
Query: 1510 VCLEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGC 1566
C++IN C + C +N +C G Q +CN P Y T D + CT I+ C+ NGGC
Sbjct: 1197 DCVDINECSLSDNLC-RNGKCVNMIGTYQCSCN--PGYQATPDRQGCTDIDECMIMNGGC 1253
Query: 1567 SEFAICNHTGQVERTCTCKPNY--IGDGFTC 1595
+ N G E C+C Y + DG +C
Sbjct: 1254 -DTQCTNSEGSYE--CSCSEGYALMPDGRSC 1281
Score = 65.1 bits (157), Expect = 9e-10
Identities = 87/350 (24%), Positives = 125/350 (35%), Gaps = 76/350 (21%)
Query: 699 THRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQ-----CPGGFS-------- 745
++RC + F +G N ++IP C D C GF
Sbjct: 1873 SYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMC 1932
Query: 746 --------NPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHG 797
+PC GNG C +++G C+C GF+ + C D ++ + +C +G
Sbjct: 1933 MDVDECERHPC-GNGTCKNTVGSYN-CLCYPGFELTHNNDCLDIDECSSFFGQ--VCRNG 1988
Query: 798 TCNNRIDS------DGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS 851
C N I S +G LT ++ C +C P TC+ G+
Sbjct: 1989 RCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSP--------GTCQNLEGSFR 2040
Query: 852 CICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGNGRDC- 908
CIC GYE C +++ C P C + C T G C+C G+ + NGR C
Sbjct: 2041 CICPPGYEVKSENCIDINECDE-DPNICLFGS-CTNT-PGGFQCLCPPGFVLSDNGRRCF 2097
Query: 909 ----------SEINNCLLPSAGGCHDNASCLYVGPGQ---NECE-CKKGFR--------- 945
E C +P A C PG+ + CE C K
Sbjct: 2098 DTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPY 2157
Query: 946 GNGI------DCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
G+G E + CLE G C C +T G + C C GY D
Sbjct: 2158 GHGTVPSLHDTREDVNECLESPGICSN-GQCINT-DGSFRCECPMGYNLD 2205
Score = 64.7 bits (156), Expect = 1e-09
Identities = 94/430 (21%), Positives = 145/430 (33%), Gaps = 97/430 (22%)
Query: 1929 PFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSAT----G 1984
PF +++ C+ P C +G+ C+ G CN+ G LD
Sbjct: 1069 PFYKDINECKA-------FPGMCT--YGK-CRNTIGSFKCRCNS-GFALDMEERNCTDID 1117
Query: 1985 ECKCNTGFNGTACEMCWPGRFGPDC---------LPCGCSDHGQCDDG-----------I 2024
EC+ + G+ + PG F +C + C D +C+
Sbjct: 1118 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNT 1177
Query: 2025 TGSGQCLCETGWT-GPSCDTQAVLPAVCTPPCSAHATCKENNTC---------ECNLDYE 2074
GS QC C G PS + V CS N C CN Y+
Sbjct: 1178 EGSFQCDCPLGHELSPSRED-----CVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQ 1232
Query: 2075 G--DGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADG 2130
D CT +D C NGGC +C+ CSC +GY DG SC +ID C +
Sbjct: 1233 ATPDRQGCTDIDECMIMNGGCD--TQCTNSEGSYECSCSEGYALMPDGRSCADIDECEN- 1289
Query: 2131 LNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
N + C PG+++C C ++ + + C+ D +C ++
Sbjct: 1290 -NPDICDGGQCTNI-PGEYRCLCYDGFMA--------SMDMKTCI-DVNECDLNSNICMF 1338
Query: 2191 HFQDTTVGVFHLRSPLGQYKLTFDKAREACAN-EAATMATYNQLSYAQKAKYH-----LC 2244
+ T G F LG + K C + + + +N +A C
Sbjct: 1339 GECENTKGSFICHCQLG---YSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSC 1395
Query: 2245 SAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMK---DVNCTCKV 2301
GW+ G + +D N + + + C C
Sbjct: 1396 REGWIGNG-----------------IKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSE 1438
Query: 2302 GYVGDGFSCS 2311
G+ GDGF+CS
Sbjct: 1439 GFTGDGFTCS 1448
Score = 64.3 bits (155), Expect = 1e-09
Identities = 75/286 (26%), Positives = 101/286 (35%), Gaps = 56/286 (19%)
Query: 1354 NVCFGNGICLDGVNGTGVCECGEGF----SGTACETCTEGKYGIHCDQACSCVHGRCNQG 1409
N+C NG+C++ +G+ C C GF +G C E C C++G C
Sbjct: 625 NMCL-NGMCINE-DGSFKCICKPGFVLAPNGRYCTDVDE------CQTPGICMNGHCINS 676
Query: 1410 PLGDGSCDCD----VGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS---CKCAAGF 1462
G CDC VG G C + C G C+ G + C CA
Sbjct: 677 E-GSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGV-CVRPFPGAVTKSECCCANPD 734
Query: 1463 QGNGTICTA-------------------------INACEISNGGCSAKADCKRTTPGRRV 1497
G G C IN C + C A C+ R
Sbjct: 735 YGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDIC-ANGICENLRGSYR- 792
Query: 1498 CTCKAGYTGD--GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYT--GDGKVC 1553
C C +GY D G C++I+ CL N CD N C T P +C C P Y + + C
Sbjct: 793 CNCNSGYEPDASGRNCIDIDECLVNRLLCD-NGLCRNT-PGSYSCTCPPGYVFRTETETC 850
Query: 1554 TLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSI 1599
IN C ++ C A N+ G C+ G C S+
Sbjct: 851 EDINEC--ESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSL 894
Score = 63.9 bits (154), Expect = 2e-09
Identities = 73/261 (27%), Positives = 100/261 (38%), Gaps = 31/261 (11%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS--CSSVCN 165
D EC GA + C+ SC + G+ CSC+EG+ G + D + CS
Sbjct: 1367 DVDECEIGAHN-CDMHASCLN-IPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQ 1424
Query: 166 CVHGVCNSGLDGDGTCECYSAYTGPKCD-KPIPECAAL--LCPENSRCSPSTEDENKLEC 222
CV+ G C C +TG + ECA LC EN +C + + EC
Sbjct: 1425 CVN------TPGSYRCACSEGFTGDGFTCSDVDECAENINLC-ENGQCL-NVPGAYRCEC 1476
Query: 223 KCLPNYRGDGKYCDPINPC-LRKICHPHAHCTYLGPNRHSCTCQEGYRGD--GQVCLPVD 279
+ D + C I+ C + IC C L P C C +GY D G C +D
Sbjct: 1477 EMGFTPASDSRSCQDIDECSFQNIC-VFGTCNNL-PGMFHCICDDGYELDRTGGNCTDID 1534
Query: 280 PCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDI----CKSDNPCHRN 335
C NC V + PG+ C C +Q GVGC + K +
Sbjct: 1535 ECADPI-NCVNGLCV---NTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGS 1590
Query: 336 ANCTT---VAPGRTECICQKG 353
+C T V R+ C C G
Sbjct: 1591 LSCNTEIGVGVSRSSCCCSLG 1611
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/323 (26%), Positives = 109/323 (33%), Gaps = 67/323 (20%)
Query: 1326 KCVRTVITRECCA-------GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGF 1378
+CV T + C GF C N N+C NG CL+ V G CEC GF
Sbjct: 1424 QCVNTPGSYRCACSEGFTGDGFTCSDVDECAENI-NLC-ENGQCLN-VPGAYRCECEMGF 1480
Query: 1379 S----GTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCD-NATTE 1433
+ +C+ E C CV G CN P G C CD G+ N T
Sbjct: 1481 TPASDSRSCQDIDE------CSFQNICVFGTCNNLP-GMFHCICDDGYELDRTGGNCTDI 1533
Query: 1434 DNCNGTCHTSANCLTNSDGTASCKCAAGFQ----GNGTICTAINACEISNGGCSAKADCK 1489
D C + N+ G C C FQ G G + + C + G +
Sbjct: 1534 DECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSC 1593
Query: 1490 RTTPG----RRVCTCKAG------------------YT----GDG-------IVCLEINP 1516
T G R C C G YT G+G I+ +I+
Sbjct: 1594 NTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDE 1653
Query: 1517 CLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNH 1574
C E G C + C T C C Y + D ++C I+ C G C N
Sbjct: 1654 CQELPGLC-QGGNCINTF-GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNT 1711
Query: 1575 TGQVERTCTCKPNY--IGDGFTC 1595
G TC C P Y + G C
Sbjct: 1712 LGNY--TCICPPEYMQVNGGHNC 1732
Score = 63.9 bits (154), Expect = 2e-09
Identities = 77/261 (29%), Positives = 101/261 (38%), Gaps = 50/261 (19%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN-C 166
+C+ PG SP G+C + +EG+ C C G+ E C D N C N C
Sbjct: 2019 ECVALPGSC-SP----GTC-QNLEGSFRCICPPGY-EVKSENCIDIN----ECDEDPNIC 2067
Query: 167 VHGVCNSGLDGDGTCECYSAY----TGPKC-DKPIPECAALLCPENSRCS-PSTEDENKL 220
+ G C + G C C + G +C D C EN +CS P + K
Sbjct: 2068 LFGSC-TNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNF--ENGKCSVPKAFNTTKA 2124
Query: 221 ECKCLPNYRGDGKYCDPINPC-------LRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQ 273
+C C G+G + DP C + +C P+ H T P+ H R D
Sbjct: 2125 KC-CCSKMPGEG-WGDPCELCPKDDEVAFQDLC-PYGHGTV--PSLHDT------REDVN 2173
Query: 274 VCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCH 333
CL P + G C + G CEC Y GV C TD C NPC
Sbjct: 2174 ECLE-SPGICSNGQC--------INTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPC- 2223
Query: 334 RNANCTTVAPGRTECICQKGY 354
N CT V G EC C +G+
Sbjct: 2224 GNGTCTNVI-GSFECNCNEGF 2243
Score = 63.9 bits (154), Expect = 2e-09
Identities = 61/197 (30%), Positives = 80/197 (40%), Gaps = 29/197 (14%)
Query: 1323 CQPKCVRTV--ITRECCAGFFGPQC-----QPCPGNAQNVCFGNGICLDGVNGTGVCECG 1375
CQ CV T+ T +C GF C G+ ++C GIC G+ CEC
Sbjct: 2543 CQFLCVNTLGGFTCKCPPGFTQHHTACIDNNEC-GSQPSLCGAKGIC-QNTPGSFSCECQ 2600
Query: 1376 EGFS----GTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431
GFS G CE E CD C HG C Q LG C C G+ + N
Sbjct: 2601 RGFSLDATGLNCEDVDE------CDGNHRCQHG-C-QNILGGYRCGCPQGYIQHYQWNQC 2652
Query: 1432 TEDN--CNGTCHTSANCLTNSDGTASCKCAAGFQGN--GTICTAINACEISNGGCSAKAD 1487
++N N SA+C N+ G+ C C +GF + + C +N C S C+
Sbjct: 2653 VDENECSNPNACGSASCY-NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCS 2711
Query: 1488 CKRTTPGRRVCTCKAGY 1504
T G +C C GY
Sbjct: 2712 ---NTEGGYLCGCPPGY 2725
Score = 61.6 bits (148), Expect = 9e-09
Identities = 80/308 (25%), Positives = 111/308 (36%), Gaps = 58/308 (18%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCV 795
D ++C G NPC GNG C + +G + C C EGF+ C D N+ C + L
Sbjct: 2213 DTDECSIG--NPC-GNGTCTNVIG-SFECNCNEGFEPGPMMNCEDINE----CAQNPLLC 2264
Query: 796 HGTCNNRIDSDGACLTGTCRDGSAGR----LCDKQTSACGPYVQFCHIHA-TCEYSNGTA 850
C N S TC G A R +C K C + C C+ GT
Sbjct: 2265 AFRCMNTFGS----YECTCPIGYALREDQKMC-KDLDECAEGLHDCESRGMMCKNLIGTF 2319
Query: 851 SCICKAGY--EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGNGR 906
CIC G DG C + + C T G N C+ G++ C C +G+ + +G
Sbjct: 2320 MCICPPGMARRPDGEGCVDENECR--TKPGICENGRCVNI-IGSYRCECNEGFQSSSSGT 2376
Query: 907 DC--------------------SEINNCLLPSAGGC-------HDNASCLYVGPGQNECE 939
+C S N + S C H C G Q +
Sbjct: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
Query: 940 CKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAV 999
C G G D I C C C +T G + C C+ GY D G + +
Sbjct: 2437 CPHG-PGYTTDGRDIDECKVMPNLC-TNGQCINT-MGSFRCFCKVGYTTD---ISGTSCI 2490
Query: 1000 ELSFLSEA 1007
+L S++
Sbjct: 2491 DLDECSQS 2498
Score = 59.3 bits (142), Expect = 5e-08
Identities = 53/200 (26%), Positives = 79/200 (39%), Gaps = 16/200 (8%)
Query: 793 LCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS 851
+C +G C N+I S C TG + L + C C +A C S G+
Sbjct: 1818 ICANGVCINQIGSFRCECPTGFSYNDLL--LVCEDIDECSNGDNLCQRNADCINSPGSYR 1875
Query: 852 CICKAGYE-GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRD--C 908
C C AG++ C + + C + P CS C+ G++ C+C G+ + C
Sbjct: 1876 CECAAGFKLSPNGACVDRNECLEI-PNVCSHGL-CVDL-QGSYQCICHNGFKASQDQTMC 1932
Query: 909 SEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR-GNGIDCEPITSCLEQTGKCHPL 967
+++ C G N +C G C C GF + DC I C G+
Sbjct: 1933 MDVDECERHPCG----NGTCKNT-VGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRN 1987
Query: 968 ASCQSTSSGVWSCVCQEGYE 987
C G + C+C EGYE
Sbjct: 1988 GRC-FNEIGSFKCLCNEGYE 2006
Score = 58.2 bits (139), Expect = 1e-07
Identities = 65/247 (26%), Positives = 93/247 (37%), Gaps = 48/247 (19%)
Query: 727 KCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ-------- 776
+C KG+ G C Q C G C G+C G C C GF G QC+
Sbjct: 165 QCQKGYIGTYCGQPVCENG----CQNGGRCI----GPNRCACVYGFTGPQCERDYRTGPC 216
Query: 777 FCSDPNKY------GPRCNKK-CLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA 829
F N+ G C K C G CR G + +T A
Sbjct: 217 FTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNI---RTGA 273
Query: 830 CGPYVQFCHIHATCEYSN-----GTASCICKAGYEGDGTL--CSEMDPCTGLTPGGCSRN 882
C + I C+ N G+ C C AG++ T C ++D C+ + PG C
Sbjct: 274 CQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCEDIDECS-IIPGIC-ET 331
Query: 883 AECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHD---NASCLYVGPG---QN 936
EC T G++ CVC +G+ + ++ + C+ G C N C PG +
Sbjct: 332 GECSNT-VGSYFCVCPRGYVTS----TDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKM 386
Query: 937 ECECKKG 943
+C C+ G
Sbjct: 387 QCCCEPG 393
Score = 57.0 bits (136), Expect = 2e-07
Identities = 97/355 (27%), Positives = 136/355 (38%), Gaps = 83/355 (23%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRC-CP-----GRWGP 107
C G+ + +G R C E +T + + G C RC CP G G
Sbjct: 643 CKPGFVLAPNG----RYCTDVDECQTPGICMNGH---CINSEGSFRCDCPPGLAVGMDGR 695
Query: 108 DCIECPGGAGSPCNG---RGSCAEGMEGNGT----CSCQEGFG-GTACETCADDNLFGPS 159
C++ S C G +G C G T C +G G C+ C N
Sbjct: 696 VCVDTH--MRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAE-- 751
Query: 160 CSSVCNCVHGVCNSGL----DGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTE 215
HG+C+SG+ DG EC D I CA +C EN R S
Sbjct: 752 -------FHGLCSSGVGITVDGRDINEC-------ALDPDI--CANGIC-ENLRGS---- 790
Query: 216 DENKLECKCLPNYRGD--GKYCDPINPCL--RKICHPHAHCTYLGPNRHSCTCQEGY--R 269
C C Y D G+ C I+ CL R +C + C P +SCTC GY R
Sbjct: 791 ----YRCNCNSGYEPDASGRNCIDIDECLVNRLLCD-NGLCRNT-PGSYSCTCPPGYVFR 844
Query: 270 GDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC--SMTDIC- 326
+ + C ++ C+ N P + C+ + G +CEC + G+ C S+ C
Sbjct: 845 TETETCEDINECESN----PCVNGACR-NNLGSFNCECSPGSKLSSTGLICIDSLKGTCW 899
Query: 327 --KSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLRELNTE-PRG 378
D+ C N N T+ ++EC G +G+ ER EL+T PRG
Sbjct: 900 LNIQDSRCEVNINGATL---KSECCATLG------AAWGSPCERC-ELDTACPRG 944
Score = 56.2 bits (134), Expect = 4e-07
Identities = 88/380 (23%), Positives = 139/380 (36%), Gaps = 108/380 (28%)
Query: 1940 RCSLVIQIPRC-CKGYFGRDCQACPGGPDAPCNNRGVCLDQYSAT--------------G 1984
RC +I RC C F Q+ G + N +G+C + T
Sbjct: 2353 RCVNIIGSYRCECNEGF----QSSSSGTECLDNRQGLCFAEVLQTICQMASSSRNLVTKS 2408
Query: 1985 ECKCNTGFN-GTACEMC-------------------WPGRFGPDC--LPCGCSDHGQCDD 2022
EC C+ G G CE+C GR +C +P C++ GQC +
Sbjct: 2409 ECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTN-GQCIN 2467
Query: 2023 GITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENN---TCECNLDY--EGD 2076
+ GS +C C+ G+T T + C+ P + CK C C Y + D
Sbjct: 2468 TM-GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQED 2526
Query: 2077 GITCTVVDFCKQ--------------------------------DNGGC-AKVARCSQKG 2103
G TC +D C+ DN C ++ + C KG
Sbjct: 2527 GKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKG 2586
Query: 2104 T------KVSCSCQKGYKGD--GHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKS 2155
SC CQ+G+ D G +C ++D C DG N C +H + G ++C C
Sbjct: 2587 ICQNTPGSFSCECQRGFSLDATGLNCEDVDEC-DG-NHRC-QHGCQNIL--GGYRCGCPQ 2641
Query: 2156 HYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDK 2215
Y+ + ++C+ +N +C C + T+G + P G +FD+
Sbjct: 2642 GYI--------QHYQWNQCVDEN-ECSNPNACGSASCYN-TLGSYKCACPSG---FSFDQ 2688
Query: 2216 AREACANEAATMATYNQLSY 2235
AC + ++ N +Y
Sbjct: 2689 FSSACHDVNECSSSKNPCNY 2708
Score = 55.5 bits (132), Expect = 7e-07
Identities = 82/319 (25%), Positives = 116/319 (36%), Gaps = 75/319 (23%)
Query: 1264 VLEIQKNRCDNNDTTIIRGRCRTCSS-ELTCPFGTKSLGNEKRRCI-------------- 1308
++ I +N C D R TCSS +++ G+KS+ RC+
Sbjct: 111 IVPICRNSC--GDGFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQK 168
Query: 1309 -YTSYFMGRRTLFIGCQP--KCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDG 1365
Y + G+ GCQ +C+ C GF GPQC+ + G C
Sbjct: 169 GYIGTYCGQPVCENGCQNGGRCIGPNRCA-CVYGFTGPQCER--------DYRTGPCFTQ 219
Query: 1366 VNGTGVCECGEGFSGTACE----TCTEGKYGIHCDQACSCVHGRCNQG---PLGDGSCDC 1418
VN C +G C T G+ H + C C +G + G+C
Sbjct: 220 VNNQ---MCQGQLTGIVCTKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ- 275
Query: 1419 DVGWRGVHCDNATTEDNCN---GTCHTSANCLTNSDGTASCKCAAGFQGNGTI--CTAIN 1473
DV D C G C NC+ N+ G+ C+C AG + + T C I+
Sbjct: 276 DV-------------DECQAIPGICQ-GGNCI-NTVGSFECRCPAGHKQSETTQKCEDID 320
Query: 1474 ACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINPCLENHGGCDK---NA 1528
C I G C +C T G C C GY + DG C++ + G C N
Sbjct: 321 ECSIIPGICET-GECSNTV-GSYFCVCPRGYVTSTDGSRCID-----QRTGMCFSGLVNG 373
Query: 1529 ECTQTGPNQAA---CNCLP 1544
C Q P + C C P
Sbjct: 374 RCAQELPGRMTKMQCCCEP 392
Score = 55.1 bits (131), Expect = 9e-07
Identities = 97/428 (22%), Positives = 140/428 (32%), Gaps = 105/428 (24%)
Query: 23 ETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTMI--TSGSVGVRDCR---YTFEV 77
+T CD S + + EC + + C GY++ T+G V +C + ++
Sbjct: 1321 KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDM 1380
Query: 78 RTYSLSLPGC-RHICRKDYLQ--------PRCCPGRW----GPDCIECPG---------- 114
L++PG + CR+ ++ C G C+ PG
Sbjct: 1381 HASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGF 1440
Query: 115 -GAGSPCNGRGSCAEGME-----------GNGTCSCQEGF-GGTACETCADDNLFGPSCS 161
G G C+ CAE + G C C+ GF + +C D + CS
Sbjct: 1441 TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDID----ECS 1496
Query: 162 SVCNCVHGVCNSGLDGDGTCECYSAY----TGPKCDKPIPECAALLCPENSRCSPSTEDE 217
CV G CN+ L G C C Y TG C I ECA + N C
Sbjct: 1497 FQNICVFGTCNN-LPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGLC---VNTP 1551
Query: 218 NKLECKCLPNYR----GDGKYCDPINPCLRKI---------CHPHAHCTYLGPNRHSCTC 264
+ EC C P+++ G G + + C K C+ +G +R SC C
Sbjct: 1552 GRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIG---VGVSRSSCCC 1608
Query: 265 QEG--YRGDGQVCLPV---------------------------DPCQINFGNCPTKSTVC 295
G + + C PV D CQ G C + +
Sbjct: 1609 SLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCIN 1668
Query: 296 KYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY- 354
+ G CEC + Y C D C + C G CIC Y
Sbjct: 1669 TF---GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPGTCYNTL-GNYTCICPPEYM 1724
Query: 355 -VGDGLTC 361
V G C
Sbjct: 1725 QVNGGHNC 1732
Score = 54.7 bits (130), Expect = 1e-06
Identities = 69/302 (22%), Positives = 96/302 (31%), Gaps = 67/302 (22%)
Query: 98 PRCCPGRWGPDCIECPGGAGSPCNG-------RGSCAEGMEGN-GTCSCQEGFGGTACET 149
P C R+ C CPG P R SC +G C+C G + C +
Sbjct: 86 PNVCGSRFHSYC--CPGWKTLPGGNQCIVPICRNSCGDGFCSRPNMCTCSSGQISSTCGS 143
Query: 150 CADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSR 209
S+ C N G D C+C Y G C +P+ E C R
Sbjct: 144 -----------KSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCENG---CQNGGR 189
Query: 210 C-SPSTEDENKLECKCLPNYRGDGKYCD---PINPCLRK-------------ICHPHAHC 252
C P+ C C+ Y G C+ PC + +C C
Sbjct: 190 CIGPN-------RCACV--YGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCC 240
Query: 253 TYLGPN-RHSC--------TCQEGYRGDGQ--VCLPVDPCQINFGNCPTKSTVCKYDGPG 301
+G H C C+ G+ + + C VD CQ G C + + + G
Sbjct: 241 ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCI---NTVG 297
Query: 302 QSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV--GDGL 359
C C ++ C D C C+ G C+C +GYV DG
Sbjct: 298 SFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTV-GSYFCVCPRGYVTSTDGS 356
Query: 360 TC 361
C
Sbjct: 357 RC 358
Score = 52.8 bits (125), Expect = 4e-06
Identities = 75/293 (25%), Positives = 106/293 (36%), Gaps = 58/293 (19%)
Query: 728 CCKGFYG-PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
CC G+ P NQC G+G C+ C C G S C +K
Sbjct: 97 CCPGWKTLPGGNQCIVPICRNSCGDGFCSRP----NMCTCSSGQISSTCG-----SKSIQ 147
Query: 787 RCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS 846
+C+ +C+ GTC +D C C+ G G C + G C C
Sbjct: 148 QCSVRCMN-GGTC-----ADDHC---QCQKGYIGTYCGQPVCENG-----CQNGGRCI-- 191
Query: 847 NGTASCICKAGYEGD--------GTLCSEMDP--CTG-LTPGGCSRNAECIKTGTGT-HT 894
G C C G+ G G ++++ C G LT C++ C G H
Sbjct: 192 -GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAWGHP 250
Query: 895 CV--------CQQGWTGNGRD--CSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF 944
C C++G+ N R C +++ C + G +C+ G EC C G
Sbjct: 251 CEMCPAQPQPCRRGFIPNIRTGACQDVDEC--QAIPGICQGGNCINT-VGSFECRCPAGH 307
Query: 945 RGNGID--CEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY--EGDGFLC 993
+ + CE I C G C C +T G + CVC GY DG C
Sbjct: 308 KQSETTQKCEDIDECSIIPGICET-GECSNTV-GSYFCVCPRGYVTSTDGSRC 358
Score = 52.8 bits (125), Expect = 4e-06
Identities = 78/309 (25%), Positives = 111/309 (35%), Gaps = 42/309 (13%)
Query: 1903 GSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGC-----RERCSLVIQI----PRCCKG 1953
GSC NTP + P G F C +CS+ +CC
Sbjct: 2070 GSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCC-- 2127
Query: 1954 YFGRDCQACPG-GPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPC 2012
C PG G PC +C + C G +GT + +CL
Sbjct: 2128 -----CSKMPGEGWGDPCE---LCPKDDEVAFQDLCPYG-HGTVPSLHDTREDVNECLES 2178
Query: 2013 -GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCT--PPCSAHATCKE---NNT 2066
G +GQC + GS +C C G+ + V C+ PC + TC +
Sbjct: 2179 PGICSNGQCIN-TDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCG-NGTCTNVIGSFE 2236
Query: 2067 CECNLDYE-GDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY--KGDGHSCTE 2123
C CN +E G + C ++ C Q+ CA RC C+C GY + D C +
Sbjct: 2237 CNCNEGFEPGPMMNCEDINECAQNPLLCA--FRCMNTFGSYECTCPIGYALREDQKMCKD 2294
Query: 2124 IDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYV--GDGLNCEPEQLPIDRCLQDNGQC 2181
+D CA+GL+ C G C C DG C E + C G C
Sbjct: 2295 LDECAEGLH-DCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDE----NECRTKPGIC 2349
Query: 2182 HADAKCVDL 2190
+ +CV++
Sbjct: 2350 E-NGRCVNI 2357
Score = 52.4 bits (124), Expect = 6e-06
Identities = 61/238 (25%), Positives = 85/238 (35%), Gaps = 57/238 (23%)
Query: 740 CPGGFSNPCSGNGQCADS------LGGNGTCICEEGFQG----SQCQFCSDPNK-YGPRC 788
CP G + G C D+ GG +C F G S+C C++P+ +G C
Sbjct: 684 CPPGLAVGMDGR-VCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSEC-CCANPDYGFGEPC 741
Query: 789 N----KKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE 844
K HG C++ + G DG C C + CE
Sbjct: 742 QPCPAKNSAEFHGLCSSGV--------GITVDGRDINECALDPDICA--------NGICE 785
Query: 845 YSNGTASCICKAGYEGD--GTLCSEMDPCTG---LTPGGCSRNAECIKTGTGTHTCVCQQ 899
G+ C C +GYE D G C ++D C L G RN G+++C C
Sbjct: 786 NLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNT------PGSYSCTCPP 839
Query: 900 GWT--GNGRDCSEINNCLLPSA--GGCHDNASCLYVGPGQNECECKKGFR--GNGIDC 951
G+ C +IN C G C +N G CEC G + G+ C
Sbjct: 840 GYVFRTETETCEDINECESNPCVNGACRNNL-------GSFNCECSPGSKLSSTGLIC 890
Score = 51.2 bits (121), Expect = 1e-05
Identities = 69/285 (24%), Positives = 96/285 (33%), Gaps = 64/285 (22%)
Query: 1358 GNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACS-----CVHGRCNQGPLG 1412
GNG C + V G+ C C GF T C + D+ S C +GRC +G
Sbjct: 1944 GNGTCKNTV-GSYNCLCYPGFELTHNNDCLD------IDECSSFFGQVCRNGRCFN-EIG 1995
Query: 1413 DGSCDCDVGWR----GVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI 1468
C C+ G+ G +C + G+C S N +G+ C C G++
Sbjct: 1996 SFKCLCNEGYELTPDGKNCIDTNECVALPGSC--SPGTCQNLEGSFRCICPPGYEVKSEN 2053
Query: 1469 CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINP--CLENHGGC 1524
C IN C+ C C T PG C C G+ + +G C + C N
Sbjct: 2054 CIDINECDEDPNICLF-GSCTNT-PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNF--- 2108
Query: 1525 DKNAECT-----QTGPNQAACNCLPAYTGDGKVCTL------------------------ 1555
+N +C+ T + C+ +P G G C L
Sbjct: 2109 -ENGKCSVPKAFNTTKAKCCCSKMPG-EGWGDPCELCPKDDEVAFQDLCPYGHGTVPSLH 2166
Query: 1556 -----INVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTC 1595
+N CL G CS N G C N G C
Sbjct: 2167 DTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRC 2211
Score = 49.3 bits (116), Expect = 5e-05
Identities = 72/296 (24%), Positives = 93/296 (31%), Gaps = 63/296 (21%)
Query: 1337 CAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCE--CGEGFSG--TACETCTEGKYG 1392
C F C CPG G C+ +C CG+GF C TC+ G+
Sbjct: 89 CGSRFHSYC--CPG--WKTLPGGNQCI-----VPICRNSCGDGFCSRPNMC-TCSSGQIS 138
Query: 1393 IHCD----QACSCVHGRC-NQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCL 1447
C Q CS RC N G D C C G+ G +C C C C+
Sbjct: 139 STCGSKSIQQCSV---RCMNGGTCADDHCQCQKGYIGTYCGQPV----CENGCQNGGRCI 191
Query: 1448 TNSDGTASCKCAAGFQG--------NGTICTAIN--ACEISNGGCSAKADCKRTTPGR-- 1495
G C C GF G G T +N C+ G T GR
Sbjct: 192 ----GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
Query: 1496 ----RVC-----TCKAGY-----TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACN 1541
+C C+ G+ TG C +++ C G C G + C
Sbjct: 248 GHPCEMCPAQPQPCRRGFIPNIRTG---ACQDVDECQAIPGICQGGNCINTVGSFECRCP 304
Query: 1542 CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI--GDGFTC 1595
+ + C I+ C G C N G C C Y+ DG C
Sbjct: 305 AGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSY--FCVCPRGYVTSTDGSRC 358
Score = 49.3 bits (116), Expect = 5e-05
Identities = 81/332 (24%), Positives = 111/332 (33%), Gaps = 73/332 (21%)
Query: 1903 GSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRC--CKGYF 1955
G+C+NT CP K QKC E E CS++ I C
Sbjct: 290 GNCINTVGSFECRCPAGHKQSETTQKC----------EDIDE-CSIIPGICETGECSNTV 338
Query: 1956 GRDCQACPGGPDAPCNNRGVCLDQYSATGEC-------KCNTGFNGTACEM---CWPGR- 2004
G CP G + C+DQ TG C +C G +M C PGR
Sbjct: 339 GSYFCVCPRGY-VTSTDGSRCIDQ--RTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRC 395
Query: 2005 FGPDCLPCGCSDHGQ------CDDGITGSG---QCLCETGWTGPSCDTQAVLPAVCTPPC 2055
+G +P C G C DG+ G G TG + + P
Sbjct: 396 WGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGG 455
Query: 2056 SAHATCKENNTCECNLDYEGDG------------ITCTVVDFCKQDNGGCAKVARCSQKG 2103
+ N + G G I +D CK C RC
Sbjct: 456 TGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLN-GRCIPTV 514
Query: 2104 TKVSCSCQKGYKGDGH-SCTEIDPCADG--LNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
+ C C GYK D + C ++D C NG C + PG + C+C +
Sbjct: 515 SSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDC-------VNTPGSYYCKCHA----- 562
Query: 2161 GLNCEPEQ---LPIDRCLQDNGQCHADAKCVD 2189
G P + + ID C+Q NG + +CV+
Sbjct: 563 GFQRTPTKQACIDIDECIQ-NGVLCKNGRCVN 593
Score = 49.3 bits (116), Expect = 5e-05
Identities = 84/322 (26%), Positives = 124/322 (38%), Gaps = 56/322 (17%)
Query: 686 SRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCC---KGFYGPDCNQCPG 742
SRC N L + C G + S C R C P+ KG D N+C
Sbjct: 905 SRCEVNINGATLKSECCATLG--AAWGSPCER-CELDTACPRGLARIKGVTCEDVNECEV 961
Query: 743 GFSNPCSGNGQCADSLGGNGTCICEEGFQ-GSQCQFCSDPNKYGPRCNKKC---LCVHGT 798
F C NG+C +S G + C C EG + C D +C K C+H
Sbjct: 962 -FPGVCP-NGRCVNSKG-SFHCECPEGLTLDGTGRVCLDIRM--EQCYLKWDEDECIHPV 1016
Query: 799 CNNRIDSDGACLTGTCRDGSA-GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAG 857
+ D C C G+A G C++ C T EY C AG
Sbjct: 1017 -PGKFRMDACC----CAVGAAWGTECEE-----------CPKPGTKEYET---LCPRGAG 1057
Query: 858 YEGDGTLCS------EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGN--GRDCS 909
+ G + + +++ C PG C+ +C T G+ C C G+ + R+C+
Sbjct: 1058 FANRGDVLTGRPFYKDINECKAF-PGMCTYG-KCRNT-IGSFKCRCNSGFALDMEERNCT 1114
Query: 910 EINNCLL-PSAGGCHDNASCLYVGPGQNECECKKGFRGNGI---DCEPITSCLEQTGKCH 965
+I+ C + P G + C+ PG ECEC +G+ + +C I C C
Sbjct: 1115 DIDECRISPDLCG---SGICVNT-PGSFECECFEGYESGFMMMKNCMDIDECERNPLLCR 1170
Query: 966 PLASCQSTSSGVWSCVCQEGYE 987
+C +T G + C C G+E
Sbjct: 1171 G-GTCVNT-EGSFQCDCPLGHE 1190
Score = 45.8 bits (107), Expect = 5e-04
Identities = 67/282 (23%), Positives = 99/282 (35%), Gaps = 46/282 (16%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGF----GGTACETC----ADDNLFGP- 158
+C E PG C G G+C G+ C C +G+ CE A + GP
Sbjct: 1653 ECQELPG----LCQG-GNCINTF-GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG 1706
Query: 159 SCSSVCNCVHGVCNSG---LDGDGTCE------CYSAYTGPKCDKPIP-ECAALLC---- 204
+C + +C ++G C CY +Y G C+ +P +C
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTY 1766
Query: 205 ----PENSRCSPSTED---ENKLECKCLPNYRGD---GKYCDPINPC--LRKICHPHAHC 252
N C P + K C +P + D GK D I+ C + IC
Sbjct: 1767 NVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVD-IDECKEIPGICANGVCI 1825
Query: 253 TYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQ 312
+G R C Y VC +D C N N ++ C + PG CEC ++
Sbjct: 1826 NQIGSFRCECPTGFSYNDLLLVCEDIDECS-NGDNLCQRNADC-INSPGSYRCECAAGFK 1883
Query: 313 NFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
G + + N C C + G +CIC G+
Sbjct: 1884 LSPNGACVDRNECLEIPNVCSHGL-CVDL-QGSYQCICHNGF 1923
Score = 43.9 bits (102), Expect = 0.002
Identities = 68/295 (23%), Positives = 90/295 (30%), Gaps = 64/295 (21%)
Query: 1948 PRCCKGYFGRDCQACP-------GGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMC 2000
P C G CP GG + + C Y+ T C+ FN T C
Sbjct: 1705 PGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGT-TCENELPFNVTKRMCC 1763
Query: 2001 WPGRFGP----DCLPC---GCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV--LPAVC 2051
G C PC G +D I G + TG + D +P +C
Sbjct: 1764 CTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDI----HTGKAVDIDECKEIPGIC 1819
Query: 2052 TPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQ 2111
+ C Y + C +D C + C + A C C C
Sbjct: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRCECA 1879
Query: 2112 KGYK-------GDGHSCTEI-DPCADGL-------------NG--------------GCH 2136
G+K D + C EI + C+ GL NG C
Sbjct: 1880 AGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECE 1939
Query: 2137 EH----ATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
H TCK T G + C C Y G L + L ID C GQ + +C
Sbjct: 1940 RHPCGNGTCKNT-VGSYNCLC---YPGFELTHNNDCLDIDECSSFFGQVCRNGRC 1990
Score = 42.4 bits (98), Expect = 0.006
Identities = 67/289 (23%), Positives = 92/289 (31%), Gaps = 85/289 (29%)
Query: 2051 CTPPCSAHATCKENNTCECNLDYE----GDGI---------------------------- 2078
C P S++ CECN+ Y+ GD I
Sbjct: 510 CIPTVSSYR-------CECNMGYKQDANGDCIDVDECTSNPCTNGDCVNTPGSYYCKCHA 562
Query: 2079 ---------TCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPC 2127
C +D C Q NG K RC C C G++ DG +C + D C
Sbjct: 563 GFQRTPTKQACIDIDECIQ-NGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVDHDEC 621
Query: 2128 ADG---LNGGCHEHATCKMTGPGKHKCECK--------SHYVGDGLNCEPEQLPID-RCL 2175
LNG C + G KC CK Y D C+ + ++ C+
Sbjct: 622 TTTNMCLNGMC-------INEDGSFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCI 674
Query: 2176 QDNGQCHADAK-----------CVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREACANEA 2224
G D CVD H + T G + + K+ CAN
Sbjct: 675 NSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPD 734
Query: 2225 ATMATYNQLSYAQ-KAKYH-LCSAGWLET--GRVAYPTAFASQNCGSGV 2269
Q A+ A++H LCS+G T GR A C +G+
Sbjct: 735 YGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGI 783
Score = 42.4 bits (98), Expect = 0.006
Identities = 63/256 (24%), Positives = 88/256 (34%), Gaps = 29/256 (11%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQ-CQFCSDPNKYGPRCNKKCLC 794
+C + PG C G G C ++ G + C C +G+ S+ + C D ++ +C
Sbjct: 1653 ECQELPG----LCQG-GNCINTFG-SFQCECPQGYYLSEDTRICEDIDECFAHPG---VC 1703
Query: 795 VHGTCNNRIDSDGACLTGTCRDGSAGRLC-DKQTSACGPYVQFCHIHATCEYSNGTASCI 853
GTC N + + + G C D + S C Y + E +
Sbjct: 1704 GPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFC--YRSYNGTTCENELPFNVTKRM 1761
Query: 854 CKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINN 913
C Y +PC TPG KT G TG D E
Sbjct: 1762 CCCTYNVGKAWNKPCEPCP--TPGTAD-----FKTICGNIPGFTFDIHTGKAVDIDECKE 1814
Query: 914 CLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGI--DCEPITSCLEQTGKCHPLASCQ 971
+P G N C+ G CEC GF N + CE I C C A C
Sbjct: 1815 --IP---GICANGVCINQ-IGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADC- 1867
Query: 972 STSSGVWSCVCQEGYE 987
S G + C C G++
Sbjct: 1868 INSPGSYRCECAAGFK 1883
Score = 41.2 bits (95), Expect = 0.013
Identities = 66/280 (23%), Positives = 93/280 (33%), Gaps = 54/280 (19%)
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGF----SGTACE--------------- 1384
+CQ PG Q G C++ G+ CEC +G+ CE
Sbjct: 1653 ECQELPGLCQG-----GNCINTF-GSFQCECPQGYYLSEDTRICEDIDECFAHPGVCGPG 1706
Query: 1385 TC--TEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHT 1442
TC T G Y C V+G N + C + G C+N + C
Sbjct: 1707 TCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRS--YNGTTCENELPFNVTKRMCCC 1764
Query: 1443 SAN-----------CLTNSDGTASCKCAAG------FQGNGTICTAINACEISNGGCSAK 1485
+ N C T GTA K G F + I+ C+ G C A
Sbjct: 1765 TYNVGKAWNKPCEPCPT--PGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC-AN 1821
Query: 1486 ADCKRTTPGRRVCTCKAGYTGDGI--VCLEINPCLENHGGCDKNAECTQTGPNQAACNCL 1543
C R C C G++ + + VC +I+ C C +NA+C + P C C
Sbjct: 1822 GVCINQIGSFR-CECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINS-PGSYRCECA 1879
Query: 1544 PAY-TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTC 1582
+ C N CL CS + G + C
Sbjct: 1880 AGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCIC 1919
Score = 38.5 bits (88), Expect = 0.086
Identities = 78/335 (23%), Positives = 105/335 (31%), Gaps = 58/335 (17%)
Query: 1270 NRCDNNDTTIIRGRCRTCSSELTCPFGTKS-LGNEKRRCIYTSYFMGRRTLFIG---CQP 1325
N C++N + G CR C S L + CI + G L I C+
Sbjct: 854 NECESNPC--VNGACRNNLGSFNCECSPGSKLSSTGLICIDS--LKGTCWLNIQDSRCEV 909
Query: 1326 KCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGIC-LDGVNGTGVCECGEGFSGTACE 1384
+ ECCA PC + G+ + GV V EC E F G
Sbjct: 910 NINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCEDVNEC-EVFPGVCPN 968
Query: 1385 -TCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTS 1443
C K HC+ C +G DG+ + R C ED C
Sbjct: 969 GRCVNSKGSFHCE---------CPEGLTLDGTGRVCLDIRMEQCYLKWDEDEC------- 1012
Query: 1444 ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRR----VCT 1499
+ + +C CA G GT C +C + PG + +C
Sbjct: 1013 IHPVPGKFRMDACCCAVGAAW-GTECE----------------ECPK--PGTKEYETLCP 1053
Query: 1500 CKAGYTGDGIVCL------EINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVC 1553
AG+ G V +IN C G C G + CN A + + C
Sbjct: 1054 RGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 1113
Query: 1554 TLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
T I+ C C N G E C C Y
Sbjct: 1114 TDIDECRISPDLCGSGICVNTPGSFE--CECFEGY 1146
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 112 bits (279), Expect = 6e-24
Identities = 82/276 (29%), Positives = 111/276 (40%), Gaps = 29/276 (10%)
Query: 1336 CCAGFFGPQCQP-CPGNAQNV-CFGNGICLDG---VNGTGVCECGEGFSGTACET--CTE 1388
C G+ G +CQ CP V C C++G + +G C C GF+G CE C E
Sbjct: 298 CSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPE 357
Query: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT 1448
G YGI CD+ C C + G C C GW G++C+ + C +C
Sbjct: 358 GLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN 417
Query: 1449 NSD---GTASCKCAAGFQGNGTICTAINACEISNGG--CSAKADCKR---TTPGRRVCTC 1500
+D T C CA GF+G C + G CS++ CK +P CTC
Sbjct: 418 GADCDSVTGKCTCAPGFKG----IDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTC 473
Query: 1501 KAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG---PNQAACNCLPAYTGDGKVCTLIN 1557
KAG+ G+ C P GC+ +C G C C P + G+ C L
Sbjct: 474 KAGW--HGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGE--KCELPC 529
Query: 1558 VCLTKNGGCSEFAICNHTGQVERT---CTCKPNYIG 1590
T C+E C+H T C C P + G
Sbjct: 530 QDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSG 565
Score = 106 bits (265), Expect = 3e-22
Identities = 101/358 (28%), Positives = 136/358 (37%), Gaps = 72/358 (20%)
Query: 1272 CDNN-DTTIIRGRCRTCSS-------ELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGC 1323
C N D + G+C TC+ CP GT + N RC GC
Sbjct: 415 CQNGADCDSVTGKC-TCAPGFKGIDCSTPCPLGTYGI-NCSSRC--------------GC 458
Query: 1324 QPKCVRTVITRECC--AGFFGPQCQ-PCPGNAQNVCFGNGICLDGVNG------TGVCEC 1374
+ V + + C AG+ G C CP FG + +NG G C C
Sbjct: 459 KNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG--FGCNLTCQCLNGGACNTLDGTCTC 516
Query: 1375 GEGFSGTACET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHCDNATT 1432
G+ G CE C +G YG++C + C C H C+ G C C GW GVHCD+
Sbjct: 517 APGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTT---GHCRCLPGWSGVHCDSVCA 573
Query: 1433 E----DNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCS----- 1483
E NC+ C+ N + S C+CA GF+ GT C I + CS
Sbjct: 574 EGRWGPNCSLPCYCK-NGASCSPDDGICECAPGFR--GTTCQRICSPGFYGHRCSQTCPQ 630
Query: 1484 ---AKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG---PNQ 1537
+ C T +C C G+T G +C E+ P C CT G P
Sbjct: 631 CVHSSGPCHHIT---GLCDCLPGFT--GALCNEVCPSGRFGKNCAGICTCTNNGTCNPID 685
Query: 1538 AACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICN-HTG----QVERTCTCKPNYIG 1590
+C C P + G C+ C + G + CN H G + C C P + G
Sbjct: 686 RSCQCYPGWIGSD--CS--QPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTG 739
Score = 105 bits (262), Expect = 6e-22
Identities = 79/302 (26%), Positives = 119/302 (39%), Gaps = 57/302 (18%)
Query: 719 CNATVKIPKCCKGFYGPDC-NQCPGG-FSNPCSGNGQCADSLGGN---GTCICEEGFQGS 773
CN C GF G C ++C G + N C QC + + G C C G+ G+
Sbjct: 160 CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGA 219
Query: 774 QCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTG--------TCRDGSAGRLCDK 825
C+ P K+GP+C ++C C +G + + + +C +G C +G G+ C +
Sbjct: 220 FCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQ 279
Query: 826 QTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGG-CSRNAE 884
+ CH TC+ + G C C GY G+ D C T G C+ +
Sbjct: 280 ECQ--------CHNGGTCDAATG--QCHCSPGYTGERC----QDECPVGTYGVLCAETCQ 325
Query: 885 CIKTGTGTH---TCVCQQGWTGN------------GRDCSEINNCLLPSAGGCHDNASCL 929
C+ G H C+C+ G+ G G C + C L + CH
Sbjct: 326 CVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCH------ 379
Query: 930 YVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQS---TSSGVWSCVCQEGY 986
P EC CK G+ +G+ C S C + SCQ+ S C C G+
Sbjct: 380 ---PMSGECACKPGW--SGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGF 434
Query: 987 EG 988
+G
Sbjct: 435 KG 436
Score = 105 bits (261), Expect = 7e-22
Identities = 97/335 (28%), Positives = 124/335 (37%), Gaps = 92/335 (27%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTA 1382
C+P C GF+G CQ Q NG D V TG C C GF G
Sbjct: 387 CKPGWSGLYCNETCSPGFYGEACQ------QICSCQNGADCDSV--TGKCTCAPGFKGID 438
Query: 1383 CET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGV----HCDNATTEDNC 1436
C T C G YGI+C C C + C+ P+ DGSC C GW GV C + T C
Sbjct: 439 CSTPCPLGTYGINCSSRCGCKNDAVCS--PV-DGSCTCKAGWHGVDCSIRCPSGTWGFGC 495
Query: 1437 NGTCH-TSANCLTNSDGTASCKCAAGFQG--------NGTI---------CTAINACEIS 1478
N TC + DGT C CA G++G +GT C+ + C +
Sbjct: 496 NLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPT 553
Query: 1479 NG------------------------GCSAKADCKR---TTPGRRVCTCKAGYTGDGIVC 1511
G CS CK +P +C C G+ G C
Sbjct: 554 TGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFR--GTTC 611
Query: 1512 LEI-NPCLENHGGCDKNAECT-QTGPNQ---AACNCLPAYTGD-----------GKVCTL 1555
I +P H +C +GP C+CLP +TG GK C
Sbjct: 612 QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAG 671
Query: 1556 INVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
I C T NG C+ ++R+C C P +IG
Sbjct: 672 ICTC-TNNGTCN---------PIDRSCQCYPGWIG 696
Score = 102 bits (253), Expect = 6e-21
Identities = 97/327 (29%), Positives = 125/327 (38%), Gaps = 64/327 (19%)
Query: 687 RCPANSEPTALFTHRC-VYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFS 745
RCP + E T H C SG YCN T C GFYG C Q
Sbjct: 367 RCPCHLENT----HSCHPMSGECACKPGWSGLYCNET-----CSPGFYGEACQQI----- 412
Query: 746 NPCS-GNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRID 804
CS NG DS+ G C C GF+G C YG C+ +C C + + +
Sbjct: 413 --CSCQNGADCDSV--TGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPV- 467
Query: 805 SDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA------SCICKAGY 858
DG+C TC+ G G C + + G + C++ TC+ NG A +C C G+
Sbjct: 468 -DGSC---TCKAGWHGVDCSIRCPS-GTWGFGCNL--TCQCLNGGACNTLDGTCTCAPGW 520
Query: 859 EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHT----CVCQQGWTGNGRD--CSEIN 912
G+ D GL C+ +C G H C C GW+G D C+E
Sbjct: 521 RGEKCELPCQDGTYGL---NCAERCDC-SHADGCHPTTGHCRCLPGWSGVHCDSVCAEGR 576
Query: 913 ---NCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGID--CEP----------ITSC 957
NC LP C + ASC P CEC GFRG C P C
Sbjct: 577 WGPNCSLPCY--CKNGASC---SPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC 631
Query: 958 LEQTGKCHPLASCQSTSSGVWSCVCQE 984
+ +G CH + G +C E
Sbjct: 632 VHSSGPCHHITGLCDCLPGFTGALCNE 658
Score = 97.1 bits (240), Expect = 2e-19
Identities = 79/288 (27%), Positives = 111/288 (38%), Gaps = 57/288 (19%)
Query: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
+CC GFY C ++ C +G+C TC CE G+ G+ C D + +GP
Sbjct: 93 QCCPGFYESG-EMCVPHCADKCV-HGRCI----APNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 787 RCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS 846
C +C C +G N I GAC C G G C+ + G Y C H C+
Sbjct: 147 HCTSRCQCKNGALCNPI--TGAC---HCAAGFRGWRCEDRCEQ-GTYGNDC--HQRCQCQ 198
Query: 847 NG------TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHT---CVC 897
NG T C C GY G C ++ P G C + C G H C C
Sbjct: 199 NGATCDHVTGECRCPPGY--TGAFCEDLCP-PGKHGPQCEQRCPCQNGGVCHHVTGECSC 255
Query: 898 QQGWTGN--GRDCSE---INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGN----- 947
GW G G+ C E NC CH+ +C +C C G+ G
Sbjct: 256 PSGWMGTVCGQPCPEGRFGKNC--SQECQCHNGGTC---DAATGQCHCSPGYTGERCQDE 310
Query: 948 ------GIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
G+ C C+ GKC+ ++ +C+C+ G+ G+
Sbjct: 311 CPVGTYGVLCAETCQCV-NGGKCYHVSG---------ACLCEAGFAGE 348
Score = 95.1 bits (235), Expect = 8e-19
Identities = 103/386 (26%), Positives = 139/386 (36%), Gaps = 71/386 (18%)
Query: 1949 RCCKGYFGRDC-QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE-MCWPGRFG 2006
RC +G +G DC Q C C N C TGEC+C G+ G CE +C PG+ G
Sbjct: 181 RCEQGTYGNDCHQRCQ------CQNGATC---DHVTGECRCPPGYTGAFCEDLCPPGKHG 231
Query: 2007 PDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD---TQAVLPAVCTPPCSAH--AT 2060
P C C C + G C +G+C C +GW G C + C+ C H T
Sbjct: 232 PQCEQRCPCQNGGVCHH---VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT 288
Query: 2061 C-KENNTCECNLDYEGDGITCTVVDFCKQDNGG--CAKVARCSQKG----TKVSCSCQKG 2113
C C C+ Y G+ D C G CA+ +C G +C C+ G
Sbjct: 289 CDAATGQCHCSPGYTGE----RCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG 344
Query: 2114 YKGDGHSCTEIDPCADGLNG-GCHEHATCKMTG-----PGKHKCECKSHYVGDGLNCEPE 2167
+ G+ E C +GL G C + C + P +C CK + GL C
Sbjct: 345 FAGER---CEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGW--SGLYCNET 399
Query: 2168 QLP--IDRCLQDNGQCHADAKCVDLHFQDTTVGVF-----HLRSPLGQYKLTFDKAREAC 2220
P Q C A C + + T F PLG Y + +R C
Sbjct: 400 CSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINC-SSRCGC 458
Query: 2221 ANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPN 2280
N+A + C AGW S C SG G +G
Sbjct: 459 KNDAVCSPVDGSCT---------CKAGWHGVD--------CSIRCPSGTWG---FGCNLT 498
Query: 2281 KSEMWDVFCYRMKDVNCTCKVGYVGD 2306
+ C + D CTC G+ G+
Sbjct: 499 CQCLNGGACNTL-DGTCTCAPGWRGE 523
Score = 89.4 bits (220), Expect = 4e-17
Identities = 75/277 (27%), Positives = 115/277 (41%), Gaps = 39/277 (14%)
Query: 99 RCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
+CCPG + + P A +GR C TC C+ G+GGT C + D + +GP
Sbjct: 93 QCCPGFYESGEMCVPHCADKCVHGR--CI----APNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 159 SCSSVCNCVHG-VCNSGLDGDGTCECYSAYTGPKC-DKPIPECAALLCPENSRC-SPSTE 215
C+S C C +G +CN G C C + + G +C D+ C + +C + +T
Sbjct: 147 HCTSRCQCKNGALCN---PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC 203
Query: 216 DENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAHCTYLGPNRH---SCTCQEGYRG 270
D EC+C P Y G +C+ + P + C C G H C+C G+ G
Sbjct: 204 DHVTGECRCPPGY--TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 271 D--GQVCLP-------VDPCQI-NFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC 320
GQ C CQ N G C + C + PG + C++ GV C
Sbjct: 262 TVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLC 320
Query: 321 SMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGD 357
+ T C + C+ + C+C+ G+ G+
Sbjct: 321 AETCQCVNGGKCYHVSGA---------CLCEAGFAGE 348
Score = 88.6 bits (218), Expect = 7e-17
Identities = 96/371 (25%), Positives = 125/371 (33%), Gaps = 93/371 (25%)
Query: 1296 GTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVR----TVITRECCAGFFGPQCQP-CPG 1350
G K++ K +C Y G + C KCV T +C G+ G C C G
Sbjct: 83 GEKTMYRRKSQCCPGFYESGEMCV-PHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDG 141
Query: 1351 NAQNV-CFGNGICLDGVNG---TGVCECGEGFSGTACE-TCTEGKYGIHCDQACSCVHG- 1404
+ C C +G TG C C GF G CE C +G YG C Q C C +G
Sbjct: 142 DHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA 201
Query: 1405 ---------RCNQGPLG-------------------------------DGSCDCDVGWRG 1424
RC G G G C C GW G
Sbjct: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 1425 VHCDNATTEDNCNGTCHTSANCL---TNSDGTASCKCAAGFQGNGTICTAINACEISNGG 1481
C E C C T T C C+ G+ G + C + G
Sbjct: 262 TVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGE----RCQDECPVGTYG 317
Query: 1482 CSAKADCKRTTPGR-----RVCTCKAGYTGD------------GIVCLEINPC-LENHGG 1523
C+ G+ C C+AG+ G+ GI C + PC LEN
Sbjct: 318 VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
Query: 1524 C-DKNAECT-QTGPNQAACN--CLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVE 1579
C + EC + G + CN C P + G+ C +C +NG A C+ V
Sbjct: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGE--ACQ--QICSCQNG-----ADCD---SVT 425
Query: 1580 RTCTCKPNYIG 1590
CTC P + G
Sbjct: 426 GKCTCAPGFKG 436
Score = 88.6 bits (218), Expect = 7e-17
Identities = 90/363 (24%), Positives = 129/363 (35%), Gaps = 72/363 (19%)
Query: 30 RCDRKSLLTIRTECRSCALNL-GVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCR 88
+C +L T CA G +C D T G+ DC + + + C
Sbjct: 153 QCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGN----DCHQRCQCQNGAT----CD 204
Query: 89 HI---CRKD------YLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQ 139
H+ CR + + C PG+ GP C + PC G C G CSC
Sbjct: 205 HVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQ-----RCPCQNGGVC---HHVTGECSCP 256
Query: 140 EGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKCDKPIP- 197
G+ GT C + FG +CS C C + G C++ G C C YTG +C P
Sbjct: 257 SGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDA---ATGQCHCSPGYTGERCQDECPV 313
Query: 198 ECAALLCPENSRCSPSTEDEN-KLECKCLPNYRGD------------GKYCDPINPCLRK 244
+LC E +C + + C C + G+ G CD PC +
Sbjct: 314 GTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE 373
Query: 245 ICHPHAHCTYLGPNRHSCTCQEGYRG-----------DGQVCLPVDPCQINFGNCPTKST 293
H P C C+ G+ G G+ C + CQ N +C + +
Sbjct: 374 NTHS------CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQ-NGADCDSVTG 426
Query: 294 VCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKG 353
C PG +C G+ CS CK+D C +P C C+ G
Sbjct: 427 KCTC-APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC---------SPVDGSCTCKAG 476
Query: 354 YVG 356
+ G
Sbjct: 477 WHG 479
Score = 80.9 bits (198), Expect = 2e-14
Identities = 78/270 (28%), Positives = 102/270 (37%), Gaps = 51/270 (18%)
Query: 1949 RCCKGYFGRDCQ-ACPGGPDAP-------CNNRGVCLDQYSATGECKCNTGFNGTACE-M 1999
+C G+ G +C AC G P C N +C TG C C GF G CE
Sbjct: 125 QCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC---NPITGACHCAAGFRGWRCEDR 181
Query: 2000 CWPGRFGPDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAH 2058
C G +G DC C C + CD +G+C C G+TG C+ P P C
Sbjct: 182 CEQGTYGNDCHQRCQCQNGATCDH---VTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQR 237
Query: 2059 ATCKENNTC-----ECNLDYEGDGITCTVVDFCKQDNGG--CAKVARCSQKGT----KVS 2107
C+ C EC+ G C C + G C++ +C GT
Sbjct: 238 CPCQNGGVCHHVTGECSCPSGWMGTVCG--QPCPEGRFGKNCSQECQCHNGGTCDAATGQ 295
Query: 2108 CSCQKGYKGDGHSCTEIDPCADGLNGG-CHEHATCKMTGPGKH---KCECKSHYVGDGLN 2163
C C GY G+ C D C G G C E C G H C C++ + G+
Sbjct: 296 CHCSPGYTGE--RCQ--DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGE--R 349
Query: 2164 CE----PEQLPIDRC-------LQDNGQCH 2182
CE PE L +C L++ CH
Sbjct: 350 CEARLCPEGLYGIKCDKRCPCHLENTHSCH 379
Score = 80.5 bits (197), Expect = 2e-14
Identities = 91/341 (26%), Positives = 117/341 (34%), Gaps = 93/341 (27%)
Query: 89 HICRKDYLQPRCCPGRWGPDCIEC--PGGAGSPCNGRGSCAEGMEGN---GTCSCQEGFG 143
H C + C PG G C E PG G C SC G + + G C+C GF
Sbjct: 376 HSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFK 435
Query: 144 GTACETCADDNLFGPSCSSVCNCV------------------HGV-----CNSGLDG--- 177
G C T +G +CSS C C HGV C SG G
Sbjct: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGC 495
Query: 178 ---------------DGTCECYSAYTGPKCDKPIPE------CAALL-CPENSRCSPSTE 215
DGTC C + G KC+ P + CA C C P+T
Sbjct: 496 NLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG 555
Query: 216 DENKLECKCLPNYRGDGKYCDPI--------NPCLRKICHPHAHCTYLGPNRHSCTCQEG 267
C+CLP + G +CD + N L C A C+ P+ C C G
Sbjct: 556 -----HCRCLPGW--SGVHCDSVCAEGRWGPNCSLPCYCKNGASCS---PDDGICECAPG 605
Query: 268 YRGD--GQVCLP---VDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPG-VGCS 321
+RG ++C P C C S C + C+C +PG G
Sbjct: 606 FRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHI---TGLCDC-------LPGFTGAL 655
Query: 322 MTDICKS---DNPCHRNANCT---TVAPGRTECICQKGYVG 356
++C S C CT T P C C G++G
Sbjct: 656 CNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIG 696
Score = 79.3 bits (194), Expect = 4e-14
Identities = 71/244 (29%), Positives = 94/244 (38%), Gaps = 56/244 (22%)
Query: 1373 ECGEGF--SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNA 1430
+C GF SG C HC A CVHGRC + +C C+ GW G +C +A
Sbjct: 93 QCCPGFYESGEMCVP--------HC--ADKCVHGRC----IAPNTCQCEPGWGGTNCSSA 138
Query: 1431 TTED----NCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG--CSA 1484
D +C C L N T +C CAAGF+G + CE G C
Sbjct: 139 CDGDHWGPHCTSRCQCKNGALCNPI-TGACHCAAGFRG----WRCEDRCEQGTYGNDCHQ 193
Query: 1485 KADCKRTTPGRRV---CTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQ---A 1538
+ C+ V C C GYT G C ++ P ++ C++ C G
Sbjct: 194 RCQCQNGATCDHVTGECRCPPGYT--GAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG 251
Query: 1539 ACNCLPAYTGD-----------GKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPN 1587
C+C + G GK C+ C NGG + A TGQ C C P
Sbjct: 252 ECSCPSGWMGTVCGQPCPEGRFGKNCS--QECQCHNGGTCDAA----TGQ----CHCSPG 301
Query: 1588 YIGD 1591
Y G+
Sbjct: 302 YTGE 305
Score = 79.3 bits (194), Expect = 4e-14
Identities = 82/298 (27%), Positives = 110/298 (36%), Gaps = 38/298 (12%)
Query: 97 QPRCCPGRWGPDCI-ECPGGA-GSPCNGRGSCAEG---MEGNGTCSCQEGFGGTACET-C 150
Q C PG G C ECP G G C C G +G C C+ GF G CE
Sbjct: 295 QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL 354
Query: 151 ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPI-PECAALLCPENSR 209
+ L+G C C C +S G C C ++G C++ P C +
Sbjct: 355 CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS 414
Query: 210 CSPSTE-DENKLECKCLPNYRGD--------GKYCDPINPCLRKICHPHAHCTYLGPNRH 260
C + D +C C P ++G G Y IN R C A C+ P
Sbjct: 415 CQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY--GINCSSRCGCKNDAVCS---PVDG 469
Query: 261 SCTCQEGYRG-DGQVCLPVD--------PCQ-INFGNCPTKSTVCKYDGPGQSHCECKEH 310
SCTC+ G+ G D + P CQ +N G C T C PG +C+
Sbjct: 470 SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTC-APGWRGEKCELP 528
Query: 311 YQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPG----RTECICQKGYVGD--GLTCY 362
Q+ G+ C+ C + CH PG + +C +G G L CY
Sbjct: 529 CQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCY 586
Score = 78.2 bits (191), Expect = 1e-13
Identities = 62/203 (30%), Positives = 82/203 (40%), Gaps = 33/203 (16%)
Query: 719 CNATVKIPKCCKGFYGPDCNQ-CPGG-FSNPCSGNGQCADSLGGNGTCI-------CEEG 769
C+ + C GF G CN+ CP G F C+G C + NGTC C G
Sbjct: 638 CHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTN----NGTCNPIDRSCQCYPG 693
Query: 770 FQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA 829
+ GS C P +GP C C C +G + DG C C G G C Q
Sbjct: 694 WIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAY--DGEC---KCTPGWTGLYC-TQRCP 747
Query: 830 CGPYVQFCHIHATCEYSNG------TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNA 883
G Y + C + C+ NG + C C+ G+ G C + P +G GC +
Sbjct: 748 LGFYGKDCAL--ICQCQNGADCDHISGQCTCRTGFM--GRHCEQKCP-SGTYGYGCRQIC 802
Query: 884 ECIKTGTGTH---TCVCQQGWTG 903
+C+ T H TC C GW G
Sbjct: 803 DCLNNSTCDHITGTCYCSPGWKG 825
Score = 76.3 bits (186), Expect = 4e-13
Identities = 92/345 (26%), Positives = 119/345 (34%), Gaps = 82/345 (23%)
Query: 1887 GGRCDTFT--TFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRER--CS 1942
G CD+ T A G G +TP CP + +C GC+ CS
Sbjct: 418 GADCDSVTGKCTCAPGFKGIDCSTP-CPLGTYGINCSSRC-----------GCKNDAVCS 465
Query: 1943 LVIQIPRCCKGYFGRDCQA-CPGGP-------DAPCNNRGVCLDQYSATGECKCNTGFNG 1994
V C G+ G DC CP G C N G C + G C C G+ G
Sbjct: 466 PVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGAC---NTLDGTCTCAPGWRG 522
Query: 1995 TACEM-CWPGRFGPDCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCT 2052
CE+ C G +G +C C CS C +G C C GW+G CD +VC
Sbjct: 523 EKCELPCQDGTYGLNCAERCDCSHADGCHPT---TGHCRCLPGWSGVHCD------SVCA 573
Query: 2053 -----PPCSAHATCK-------ENNTCECNLDYEGD-----------GITCT-VVDFCKQ 2088
P CS CK ++ CEC + G G C+ C
Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH 633
Query: 2089 DNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTG-- 2145
+G C + C C G+ G C E+ C G G C TC G
Sbjct: 634 SSGPCHHITGL--------CDCLPGF--TGALCNEV--CPSGRFGKNCAGICTCTNNGTC 681
Query: 2146 -PGKHKCECKSHYVGDGLN--CEPEQLPIDRCLQDNGQCHADAKC 2187
P C+C ++G + C P C+ CH A C
Sbjct: 682 NPIDRSCQCYPGWIGSDCSQPCPPAHWG-PNCIH-TCNCHNGAFC 724
Score = 69.3 bits (168), Expect = 5e-11
Identities = 69/254 (27%), Positives = 103/254 (40%), Gaps = 48/254 (18%)
Query: 45 SCALNLGV-KCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI---CRKDYLQPRC 100
SC+ + G+ +C G+ G+ R C F S + P C H C C
Sbjct: 592 SCSPDDGICECAPGFR----GTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDC 647
Query: 101 CPGRWGPDCIE-CPGGA-GSPCNGRGSCAEGMEGNGTCS-------CQEGFGGTACETCA 151
PG G C E CP G G C G +C NGTC+ C G+ G+ C
Sbjct: 648 LPGFTGALCNEVCPSGRFGKNCAGICTCTN----NGTCNPIDRSCQCYPGWIGSDCSQPC 703
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP------ECAALL-C 204
+GP+C CNC +G S DG+ C+C +TG C + P +CA + C
Sbjct: 704 PPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFYGKDCALICQC 761
Query: 205 PENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPC------LRKICH--PHAHCTYLG 256
+ C D +C C + G++C+ P R+IC ++ C ++
Sbjct: 762 QNGADC-----DHISGQCTCRTGFM--GRHCEQKCPSGTYGYGCRQICDCLNNSTCDHI- 813
Query: 257 PNRHSCTCQEGYRG 270
+C C G++G
Sbjct: 814 --TGTCYCSPGWKG 825
Score = 67.0 bits (162), Expect = 2e-10
Identities = 62/245 (25%), Positives = 88/245 (35%), Gaps = 41/245 (16%)
Query: 1897 DASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFG 1956
D EC +C R P +C P + G C + + C G+ G
Sbjct: 597 DGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG---PCHHITGLCDCLPGFTG 653
Query: 1957 RDC-QACPGGPDAP-------CNNRGVC--LDQYSATGECKCNTGFNGTACEM-CWPGRF 2005
C + CP G C N G C +D+ C+C G+ G+ C C P +
Sbjct: 654 ALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR-----SCQCYPGWIGSDCSQPCPPAHW 708
Query: 2006 GPDCL-PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN 2064
GP+C+ C C + C G+C C GWTG C TQ C+ C+
Sbjct: 709 GPNCIHTCNCHNGAFCS---AYDGECKCTPGWTGLYC-TQRCPLGFYGKDCALICQCQNG 764
Query: 2065 NTCECNLDYEGDGITCT---VVDFCKQD------NGGCAKVARCSQKGT----KVSCSCQ 2111
C D+ TC + C+Q GC ++ C T +C C
Sbjct: 765 ADC----DHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCS 820
Query: 2112 KGYKG 2116
G+KG
Sbjct: 821 PGWKG 825
Score = 65.5 bits (158), Expect = 7e-10
Identities = 44/142 (30%), Positives = 61/142 (42%), Gaps = 17/142 (11%)
Query: 1335 ECCAGFFGPQC-QPCPG-----NAQNVC-FGNGICLDGVNGTGVCECGEGFSGTAC-ETC 1386
+C G+ G C QPCP N + C NG +G C+C G++G C + C
Sbjct: 689 QCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRC 746
Query: 1387 TEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSAN 1445
G YG C C C +G C+ G C C G+ G HC+ C +
Sbjct: 747 PLGFYGKDCALICQCQNGADCDHI---SGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD 803
Query: 1446 CLTNSDG---TASCKCAAGFQG 1464
CL NS T +C C+ G++G
Sbjct: 804 CLNNSTCDHITGTCYCSPGWKG 825
Score = 64.7 bits (156), Expect = 1e-09
Identities = 39/101 (38%), Positives = 48/101 (47%), Gaps = 13/101 (12%)
Query: 1949 RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM-CWPGRFGP 2007
RC G++G+DC C N C D S G+C C TGF G CE C G +G
Sbjct: 745 RCPLGFYGKDCALI-----CQCQNGADC-DHIS--GQCTCRTGFMGRHCEQKCPSGTYGY 796
Query: 2008 DCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVL 2047
C C C ++ CD ITG+ C C GW G CD V+
Sbjct: 797 GCRQICDCLNNSTCDH-ITGT--CYCSPGWKGARCDQAGVI 834
Score = 63.9 bits (154), Expect = 2e-09
Identities = 67/240 (27%), Positives = 89/240 (37%), Gaps = 43/240 (17%)
Query: 1949 RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPG-RFGP 2007
+CC G++ P D + R + A C+C G+ GT C G +GP
Sbjct: 93 QCCPGFYESGEMCVPHCADKCVHGRCI------APNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 2008 DCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCD---TQAVLPAVCTPPCSAH--ATC 2061
C C C + C+ ITG+ C C G+ G C+ Q C C ATC
Sbjct: 147 HCTSRCQCKNGALCNP-ITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC 203
Query: 2062 KENNTCECNLDYEGDGITCTVVDFCKQDNGG--CAKVARCSQKG----TKVSCSCQKGYK 2115
++ T EC G C D C G C + C G CSC G+
Sbjct: 204 -DHVTGECRCPPGYTGAFCE--DLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWM 260
Query: 2116 GDGHSCTEIDPCADGLNG-------GCHEHATC-KMTGPGKHKCECKSHYVGDGLNCEPE 2167
G C + PC +G G CH TC TG +C C Y G+ C+ E
Sbjct: 261 GT--VCGQ--PCPEGRFGKNCSQECQCHNGGTCDAATG----QCHCSPGYTGE--RCQDE 310
Score = 63.2 bits (152), Expect = 3e-09
Identities = 38/111 (34%), Positives = 48/111 (43%), Gaps = 15/111 (13%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVC-FGNGICLDGVNGTGVCECGEGFSGT 1381
C P T+ C GF+G C +C NG D ++G C C GF G
Sbjct: 733 CTPGWTGLYCTQRCPLGFYGKDCAL-------ICQCQNGADCDHISGQ--CTCRTGFMGR 783
Query: 1382 ACET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHCDNA 1430
CE C G YG C Q C C++ C+ G+C C GW+G CD A
Sbjct: 784 HCEQKCPSGTYGYGCRQICDCLNNSTCDHIT---GTCYCSPGWKGARCDQA 831
Score = 58.5 bits (140), Expect = 8e-08
Identities = 85/332 (25%), Positives = 120/332 (36%), Gaps = 58/332 (17%)
Query: 2000 CWPGRF--GPDCLPCGCSD---HGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPP 2054
C PG + G C+P C+D HG+C C CE GW G +C + A P
Sbjct: 94 CCPGFYESGEMCVP-HCADKCVHGRC----IAPNTCQCEPGWGGTNC-SSACDGDHWGPH 147
Query: 2055 CSAHATCKENNTCE-----CNLDYEGDGITCTVVDFCKQDNGG--CAKVARCSQKGT--- 2104
C++ CK C C+ G C D C+Q G C + +C T
Sbjct: 148 CTSRCQCKNGALCNPITGACHCAAGFRGWRCE--DRCEQGTYGNDCHQRCQCQNGATCDH 205
Query: 2105 -KVSCSCQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTGPGKH---KCECKSHYVG 2159
C C GY G C ++ C G +G C + C+ G H +C C S ++G
Sbjct: 206 VTGECRCPPGY--TGAFCEDL--CPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMG 261
Query: 2160 D--GLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAR 2217
G C PE C Q+ QCH C D G H SP T ++ +
Sbjct: 262 TVCGQPC-PEGRFGKNCSQE-CQCHNGGTC------DAATGQCHC-SP----GYTGERCQ 308
Query: 2218 EACANEAATMATYNQLSYAQKAK-YHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYG 2276
+ C + K YH+ A E G FA + C + + YG
Sbjct: 309 DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG-------FAGERCEARLCPEGLYG 361
Query: 2277 PRPNK---SEMWDVFCYRMKDVNCTCKVGYVG 2305
+ +K + + C CK G+ G
Sbjct: 362 IKCDKRCPCHLENTHSCHPMSGECACKPGWSG 393
Score = 57.8 bits (138), Expect = 1e-07
Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 44/139 (31%)
Query: 94 DYLQPRCCPGRWGPDCI----------------EC---PGGAGSPCNGRGSCAEGMEG-- 132
D QP C P WGP+CI EC PG G C R C G G
Sbjct: 698 DCSQP-CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQR--CPLGFYGKD 754
Query: 133 ----------------NGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLD 176
+G C+C+ GF G CE +G C +C+C++ NS D
Sbjct: 755 CALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN---NSTCD 811
Query: 177 G-DGTCECYSAYTGPKCDK 194
GTC C + G +CD+
Sbjct: 812 HITGTCYCSPGWKGARCDQ 830
Score = 33.9 bits (76), Expect = 2.1
Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 39/125 (31%)
Query: 689 PANSEPTALFTHRCVYSGRFGSLKSG---CARYCNATVKIPKCCKGFYGPDCN---QCPG 742
PA+ P + T C ++G F S G C +C GFYG DC QC
Sbjct: 705 PAHWGPNCIHTCNC-HNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQN 763
Query: 743 G-----FSNPCS---------------------GNGQCADSLGGN------GTCICEEGF 770
G S C+ G Q D L + GTC C G+
Sbjct: 764 GADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGW 823
Query: 771 QGSQC 775
+G++C
Sbjct: 824 KGARC 828
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 112 bits (279), Expect = 6e-24
Identities = 93/308 (30%), Positives = 115/308 (37%), Gaps = 56/308 (18%)
Query: 1336 CCAGFFGPQCQ-PCPG-----NAQNVC-FGNGICLDGVNGTGVCECGEGFSGTACET-CT 1387
C GF G C CP N +VC G G D V GT C C G +G CE C
Sbjct: 1236 CPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRCERGCP 1293
Query: 1388 EGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCL 1447
+ ++G+ C+ CSC +G +GSC C +GW G HC+ A CH +C
Sbjct: 1294 QNRFGVGCEHTCSCRNGGLCHA--SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
Query: 1448 TNS---DGTASCKCAAGFQGNGTICTAINACE------ISNGGCSAKADCKRTTP----- 1493
NS T +C+C GF G ACE GC C+ P
Sbjct: 1352 NNSTCEPATGTCRCGPGFYG--------QACEHPCPPGFHGAGCQGLCWCQHGAPCDPIS 1403
Query: 1494 GRRVCTCKAGYTGD----GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGD 1549
GR C C AG+ G G CD A C P C C P +
Sbjct: 1404 GR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPC---DPVTGLCLCPPGRS-- 1456
Query: 1550 GKVCTL------INVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQEL 1603
G C L T + C A C+ V C C Y+G TCR L
Sbjct: 1457 GATCNLDCRRGQFGPSCTLHCDCGGGADCD---PVSGQCHCVDGYMGP--TCREGGPLRL 1511
Query: 1604 PKNPKTSQ 1611
P+NP +Q
Sbjct: 1512 PENPSLAQ 1519
Score = 103 bits (258), Expect = 2e-21
Identities = 112/417 (26%), Positives = 147/417 (35%), Gaps = 101/417 (24%)
Query: 1823 AVDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLI 1882
A P A ++ G E +C AG D GQ C + +G++C
Sbjct: 698 ACTCPVGVACDSVSG-ECGKRCPAGFQGEDC---GQECPVG----------TFGVNCSSS 743
Query: 1883 DPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCS 1942
G C T G+C CP P + C + P R GC+E C
Sbjct: 744 CSCGGAPCHGVT-----GQC-------RCP----PGRTGEDCEADCPEGRWGLGCQEICP 787
Query: 1943 LVIQIPRC---------CKGYFGRDCQ-ACPGGPDAP-CNNRGVCLDQ---YSATGECKC 1988
RC G+ G CQ CP G P C R C + + ATG C C
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSC 847
Query: 1989 NTGFNGTACEM-CWPGRFGPDCL-PCGCS-DHGQCDDGITGSGQCLCETGWTGPSCDTQA 2045
G+ G +C+ C G +GPDC PC CS HG CD SG CLCE G+ GP C+ Q
Sbjct: 848 APGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD---AISGLCLCEAGYVGPRCEQQC 904
Query: 2046 VLPAVCTPPCSAHATCKE-------NNTCECNLDYEGDGI--TCTVVDFCKQDNGGCAKV 2096
P C C+ + C C + G C F C
Sbjct: 905 P-QGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCT 963
Query: 2097 ARCSQKGTKVSCSCQKGYKGD-----------GHSCTEIDPCADG-----LNGGCH---- 2136
A + SC C G +G GH+C++ C +G ++G CH
Sbjct: 964 AGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPG 1023
Query: 2137 -EHATCKMTGPG-------KHKCECKSHYVGD-------------GLNCEPEQLPID 2172
+C P +H C C++ D GL CE E LP D
Sbjct: 1024 WMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRD 1080
Score = 102 bits (255), Expect = 4e-21
Identities = 83/286 (29%), Positives = 109/286 (38%), Gaps = 36/286 (12%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQ-PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
C P R C G +GP C PC N G+G C D ++G +C C G+ G
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPC-----NCSAGHGSC-DAISG--LCLCEAGYVGP 898
Query: 1382 ACET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
CE C +G +G C+Q C C HG C+ G+C C GWRG C++A
Sbjct: 899 RCEQQCPQGHFGPGCEQRCQCQHGAACDHV---SGACTCPAGWRGTFCEHACPAGFFGLD 955
Query: 1440 CHTSANCLTNSDGTA---SCKCAAGFQGNGTICTAINACEISNGGCSAKADC---KRTTP 1493
C ++ NC + A SC C AG G C CS C P
Sbjct: 956 CRSACNCTAGAACDAVNGSCLCPAG--RRGPRCAETCPAHTYGHNCSQACACFNGASCDP 1013
Query: 1494 GRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG---PNQAACNCLPAYTGDG 1550
C C G+ G CL+ P C + C G P C C + G
Sbjct: 1014 VHGQCHCAPGWMGPS--CLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA 1071
Query: 1551 --KVCTL--INVCLTKNGGCSEFAICN-HTGQVERTCTCKPNYIGD 1591
K C + +GGC +C+ HTG+ C C + GD
Sbjct: 1072 CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGR----CLCPAGWTGD 1113
Score = 97.4 bits (241), Expect = 2e-19
Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 64/312 (20%)
Query: 719 CNATVKIPKCCKGFYGPDCNQC--PGGFSNPCSGNGQCADSLGG----NGTCICEEGFQG 772
C+ +C GF G C Q PG F C+ QC GTC C G+ G
Sbjct: 1140 CHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHG 1199
Query: 773 SQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTG--------TCRDGSAGRLCD 824
CQ P +YGP C + C C++G + C TG TC G G C
Sbjct: 1200 PSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNC- 1258
Query: 825 KQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAE 884
T CG C A C+ GT C+C G G C P GC
Sbjct: 1259 --THVCG-----CGQGAACDPVTGT--CLCPPGRA--GVRCERGCPQNRFGV-GCEHTCS 1306
Query: 885 CIKTG---TGTHTCVCQQGWTGNGRDCSEINNCLLPSAGG-----------CHDNASCLY 930
C G +C C GWTG +C L G CH+N++C
Sbjct: 1307 CRNGGLCHASNGSCSCGLGWTG--------RHCELACPPGRYGAACHLECSCHNNSTC-- 1356
Query: 931 VGPGQNECECKKGFRG-----------NGIDCEPITSCLEQTGKCHPLASCQSTSSGVWS 979
P C C GF G +G C+ + C + C P++ +G
Sbjct: 1357 -EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWC-QHGAPCDPISGRCLCPAGFHG 1414
Query: 980 CVCQEGYEGDGF 991
C+ G E F
Sbjct: 1415 HFCERGCEPGSF 1426
Score = 94.7 bits (234), Expect = 1e-18
Identities = 91/331 (27%), Positives = 125/331 (37%), Gaps = 101/331 (30%)
Query: 728 CCKGFYGPDCNQCPGGFSNPCS---GNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKY 784
C G +GPDC S+PC+ G+G C D++ +G C+CE G+ G +C+ +
Sbjct: 860 CDTGHWGPDC-------SHPCNCSAGHGSC-DAI--SGLCLCEAGYVGPRCEQQCPQGHF 909
Query: 785 GPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQ----------TSACGPYV 834
GP C ++C C HG + + GAC TC G G C+ SAC
Sbjct: 910 GPGCEQRCQCQHGAACDHV--SGAC---TCPAGWRGTFCEHACPAGFFGLDCRSACN--- 961
Query: 835 QFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPG-GCSRNAECIKTGT--G 891
C A C+ NG SC+C AG G C+E C T G CS+ C +
Sbjct: 962 --CTAGAACDAVNG--SCLCPAGRR--GPRCAE--TCPAHTYGHNCSQACACFNGASCDP 1013
Query: 892 TH-TCVCQQGWTG-----------------------NGRDCSEIN-NCLLPSA------- 919
H C C GW G NG C ++ +C P
Sbjct: 1014 VHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACE 1073
Query: 920 ---------GGCHDNASCLYVG---PGQNECECKKGFRGNGIDCEPITSCLE-------- 959
GC + CL G P C C G+ G+ C+ + CL
Sbjct: 1074 KECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGD--KCQ--SPCLRGWFGEACA 1129
Query: 960 QTGKCHPLASCQSTSSGVWSCVCQEGYEGDG 990
Q C P A+C + +C C G+ G G
Sbjct: 1130 QRCSCPPGAACHHVTG---ACRCPPGFTGSG 1157
Score = 93.6 bits (231), Expect = 2e-18
Identities = 80/283 (28%), Positives = 106/283 (37%), Gaps = 74/283 (26%)
Query: 90 ICRKDYLQPRC---CP-GRWGPDCIE-CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGG 144
+C Y+ PRC CP G +GP C + C G+ C+ +G C+C G+ G
Sbjct: 890 LCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD---------HVSGACTCPAGWRG 940
Query: 145 TACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLC 204
T CE FG C S CNC G + +G+C C + GP+C A C
Sbjct: 941 TFCEHACPAGFFGLDCRSACNCTAGAACDAV--NGSCLCPAGRRGPRC--------AETC 990
Query: 205 PENS---RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCT--YLGPNR 259
P ++ CS + C C +G CDP+ H HC ++GP
Sbjct: 991 PAHTYGHNCSQA--------CACF-----NGASCDPV--------HGQCHCAPGWMGP-- 1027
Query: 260 HSC--TCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPG 317
SC C G GD C CQ N G C P HC C E +
Sbjct: 1028 -SCLQACPAGLYGDN--CRHSCLCQ-NGGTC----------DPVSGHCACPEGWAGLACE 1073
Query: 318 VGCSMTDI---CKSDNPCHRNANCTTVAPGRTECICQKGYVGD 357
C D+ C+ C C P C+C G+ GD
Sbjct: 1074 KECLPRDVRAGCRHSGGCLNGGLCD---PHTGRCLCPAGWTGD 1113
Score = 93.6 bits (231), Expect = 2e-18
Identities = 93/317 (29%), Positives = 115/317 (36%), Gaps = 55/317 (17%)
Query: 1887 GGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQ 1946
G C + C CP G +Q C P E C + C +
Sbjct: 1125 GEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQAC----PPGSFGEDCAQMCQCPGE 1180
Query: 1947 IPRC---------CKGYFGRDCQA-CPGGPDAP-------CNNRGVCLDQYSATGECKCN 1989
P C GY G CQ CP G P C N G C +ATG C+C
Sbjct: 1181 NPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSC---DAATGACRCP 1237
Query: 1990 TGFNGTACEM-CWPGRFGPDCL-PCGCSDHGQCDDGITGSGQCLCETGWTGPSCD---TQ 2044
TGF GT C + C GRFGP+C CGC CD +TG+ CLC G G C+ Q
Sbjct: 1238 TGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDP-VTGT--CLCPPGRAGVRCERGCPQ 1294
Query: 2045 AVLPAVCTPPCSAH--ATC-KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQ 2101
C CS C N +C C L + G C + C G A CS
Sbjct: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR--HCELA--CPPGRYGAACHLECSC 1350
Query: 2102 KGTKV------SCSCQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTGPG---KHKC 2151
+C C G+ G +C PC G +G GC C+ P +C
Sbjct: 1351 HNNSTCEPATGTCRCGPGFY--GQACEH--PCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Query: 2152 ECKSHYVGD--GLNCEP 2166
C + + G CEP
Sbjct: 1407 LCPAGFHGHFCERGCEP 1423
Score = 92.4 bits (228), Expect = 5e-18
Identities = 73/284 (25%), Positives = 110/284 (38%), Gaps = 23/284 (8%)
Query: 91 CRKDYLQPRCCPGRWGPDC-IECPGGAGSP-CNGRGSCAEGM-----EGNGTCSCQEGFG 143
C + Y C PG +G C + CP A P C+ C + + +G+CSC+ GF
Sbjct: 619 CHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFR 678
Query: 144 GTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP-ECAAL 202
G C+ + FGP C C C GV + G+ C + + G C + P +
Sbjct: 679 GERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGV 738
Query: 203 LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP------CLRKICHPHAHCTYLG 256
C + C + +C+C P G+ C+ P ++IC H
Sbjct: 739 NCSSSCSCGGAPCHGVTGQCRCPPGRTGED--CEADCPEGRWGLGCQEICPACQHAARCD 796
Query: 257 PNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDG---PGQSHCECKEHYQN 313
P +C C G+ G C V P +C T+ + C DG P HC C +
Sbjct: 797 PETGACLCLPGFVGSR--CQDVCPAGWYGPSCQTRCS-CANDGHCHPATGHCSCAPGWTG 853
Query: 314 FVPGVGCSMTDICKS-DNPCHRNANCTTVAPGRTECICQKGYVG 356
F C +PC+ +A + C+C+ GYVG
Sbjct: 854 FSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVG 897
Score = 91.7 bits (226), Expect = 9e-18
Identities = 103/419 (24%), Positives = 142/419 (33%), Gaps = 74/419 (17%)
Query: 606 PHIRSMANQLIQFNTTDNGQILANDVAMEEIEITAKNGRIYTLTGVLIPPSIVPILPHRC 665
PHI + ++L Q D DV +E E + T V + S C
Sbjct: 472 PHIAVLQDELPQLFQDD-------DVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTC 524
Query: 666 DETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFG---SLKSGCAR--YCN 720
D+ + GTC L+ C T L + FG S C C+
Sbjct: 525 DDCRNG---GTC----LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCD 577
Query: 721 ATVKIPKCCKGFYGPDCNQ-CPGGFSNP-------CSGNGQCADSLGGNGTCICEEGFQG 772
+ +C G G +C CP G+ C+ G+C G C+C+ G G
Sbjct: 578 SVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGA---CLCDPGLYG 634
Query: 773 SQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--C 830
C P +GP C+++C CV + DG+C +C+ G G C +
Sbjct: 635 RFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSC---SCKAGFRGERCQAECELGYF 691
Query: 831 GP---YVQFCHIHATCEYSNGTASCICKAGYEGD-----------GTLCSEMDPCTGLTP 876
GP C + C+ +G C AG++G+ G CS C G
Sbjct: 692 GPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPC 751
Query: 877 GGCSRNAECIKTGTGTH-TCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQ 935
G + C TG C +G G G C EI C A C P
Sbjct: 752 HGVTGQCRCPPGRTGEDCEADCPEGRWGLG--CQEI-------CPACQHAARC---DPET 799
Query: 936 NECECKKGFRGN-----------GIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQ 983
C C GF G+ G C+ SC G CHP S + G CQ
Sbjct: 800 GACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCAND-GHCHPATGHCSCAPGWTGFSCQ 857
Score = 91.7 bits (226), Expect = 9e-18
Identities = 94/340 (27%), Positives = 117/340 (34%), Gaps = 51/340 (15%)
Query: 1282 GRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRR----TLFIG-CQPKCVRTVITREC 1336
G C S CP G L EK C+ G R L G C P R + C
Sbjct: 1052 GTCDPVSGHCACPEGWAGLACEKE-CLPRDVRAGCRHSGGCLNGGLCDPHTGRCL----C 1106
Query: 1337 CAGFFGPQCQ-PC-PGNAQNVCFGNGICLDGV---NGTGVCECGEGFSGTACE-TCTEGK 1390
AG+ G +CQ PC G C C G + TG C C GF+G+ CE C G
Sbjct: 1107 PAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGS 1166
Query: 1391 YGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNS 1450
+G C Q C C P G+C C G+ G C C CL
Sbjct: 1167 FGEDCAQMCQCPGENPACHP-ATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
Query: 1451 D---GTASCKCAAGFQGN-----------GTICTAINACEISNGGCSAKADCKRTTPGRR 1496
T +C+C GF G G CT + C GC A C P
Sbjct: 1226 SCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCT--HVC-----GCGQGAAC---DPVTG 1275
Query: 1497 VCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG---PNQAACNCLPAYTGDGKVC 1553
C C G G+ C P GC+ C G + +C+C +T G+ C
Sbjct: 1276 TCLCPPGRA--GVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWT--GRHC 1331
Query: 1554 TLINVCLTKNGGCSEFAICNHTGQVE---RTCTCKPNYIG 1590
L C C++ E TC C P + G
Sbjct: 1332 ELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYG 1371
Score = 90.5 bits (223), Expect = 2e-17
Identities = 94/332 (28%), Positives = 125/332 (37%), Gaps = 87/332 (26%)
Query: 706 GRFGSLKSGCARYCNATVKIPKC---------CKGFYGPDCNQ-CPGGFSNP-------C 748
GR+G GC C A +C GF G C CP G+ P C
Sbjct: 776 GRWGL---GCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSC 832
Query: 749 SGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCV--HGTCNNRIDSD 806
+ +G C + G C C G+ G CQ D +GP C+ C C HG+C+
Sbjct: 833 ANDGHCHPA---TGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD---AIS 886
Query: 807 GACLTGTCRDGSAGRLCDKQT------SACGPYVQFCHIHATCEYSNGTASCICKAGYEG 860
G CL C G G C++Q C Q C A C++ +G +C C AG+
Sbjct: 887 GLCL---CEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAACDHVSG--ACTCPAGWR- 939
Query: 861 DGTLCSEMDPC--TGL---TPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEI---- 911
GT C P GL + C+ A C +C+C G G C+E
Sbjct: 940 -GTFCEHACPAGFFGLDCRSACNCTAGAAC---DAVNGSCLCPAG--RRGPRCAETCPAH 993
Query: 912 ---NNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRG-----------NGIDCEPITSC 957
+NC A C + ASC P +C C G+ G G +C SC
Sbjct: 994 TYGHNC--SQACACFNGASC---DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCR--HSC 1046
Query: 958 LEQT-GKCHPLASCQSTSSGVWSCVCQEGYEG 988
L Q G C P++ C C EG+ G
Sbjct: 1047 LCQNGGTCDPVSG---------HCACPEGWAG 1069
Score = 89.0 bits (219), Expect = 6e-17
Identities = 94/336 (27%), Positives = 140/336 (41%), Gaps = 55/336 (16%)
Query: 1287 CSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFI---------GCQPKCVRTVITREC- 1336
CS+ L C G + + + C F G R + GCQ +CV T + C
Sbjct: 128 CSASL-CFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCE 186
Query: 1337 CAGFFGPQCQPCPGNAQNVC-FGNGICLDGVNGTGV----CECGEGFSGTACETCTEGKY 1391
C F A N C GNG C + C+C GF + +G++
Sbjct: 187 CKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF-----QLQEDGRH 241
Query: 1392 GIH----CDQACSCVHGRCNQGPLGDGSCDCDVGWR----GVHCDNATTEDNCNGTCHTS 1443
+ ++ SC+H RC Q G C+C VG++ G C++ D C
Sbjct: 242 CVRRSPCANRNGSCMH-RC-QVVRGLARCECHVGYQLAADGKACEDV---DECAAGLAQC 296
Query: 1444 ANCLTNSDGTASCKCAAGFQ--GNGTICTAI-----NACEISNGGCSAKADCKRTTPGRR 1496
A+ N+ G+ C C AG++ +G C I N+CE +NGGCS C T+ G
Sbjct: 297 AHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGP- 353
Query: 1497 VCTCKAGYT--GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKV 1552
+CTC GY D C++++ C ++ C + CT P C C Y + DG
Sbjct: 354 LCTCPRGYELDTDQRTCIDVDDCADSP--CCQQV-CTNN-PGGYECGCYAGYRLSADGCG 409
Query: 1553 CTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
C ++ C + GGC E N G + C+C+ Y
Sbjct: 410 CEDVDECASSRGGC-EHHCTNLAGSFQ--CSCEAGY 442
Score = 87.4 bits (215), Expect = 2e-16
Identities = 99/385 (25%), Positives = 137/385 (35%), Gaps = 83/385 (21%)
Query: 1272 CDNNDTTIIRGRCRTCSSELT---------CPFGTKSLGNEKRRCIYTSYFMGRRTLFIG 1322
C + T++ GR + C L+ C + +G+E+R T Y+MG R ++
Sbjct: 48 CAEQELTLV-GRRQPCVQALSHTVPVWKAGCGWQAWCVGHERR----TVYYMGYRQVYT- 101
Query: 1323 CQPKCVRTVITRECCAGFFG-PQCQPCPGN--AQNVCFGNGICLDGVNGTGVCECGEGFS 1379
RTV+ CC G+ P + C + ++CF G C+ G C C GF
Sbjct: 102 ---TEARTVL--RCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPG--SAQPCHCPPGFQ 154
Query: 1380 GTACE-----------------TCTEGKYGIHC---------DQAC----SCVHGR---- 1405
G C+ T G Y C + C SC G
Sbjct: 155 GPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQ 214
Query: 1406 --CNQGPLGDGSCDCDVGWR----GVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCA 1459
C Q + C C G++ G HC + N NG+C + G A C+C
Sbjct: 215 HHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVR---GLARCECH 271
Query: 1460 AGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCLEI- 1514
G+Q +G C ++ C C+ T G C C AGY DG C I
Sbjct: 272 VGYQLAADGKACEDVDECAAGLAQCAHGC---LNTQGSFKCVCHAGYELGADGRQCYRIE 328
Query: 1515 ----NPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1570
N C N+GGC T GP C C Y D T I+V + C +
Sbjct: 329 MEIVNSCEANNGGCSHGCSHTSAGP---LCTCPRGYELDTDQRTCIDVDDCADSPCCQQV 385
Query: 1571 ICNHTGQVERTCTCKPNYIGDGFTC 1595
N+ G E C DG C
Sbjct: 386 CTNNPGGYECGCYAGYRLSADGCGC 410
Score = 86.3 bits (212), Expect = 4e-16
Identities = 87/332 (26%), Positives = 115/332 (34%), Gaps = 85/332 (25%)
Query: 1335 ECCAGFFGPQC-QPCPGNA--QNVCFG----NGICLDGVNGTGVCECGEGFSGTACET-C 1386
+C G+ G C + CP + +N F NG D V TG C C G SGT CE C
Sbjct: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSV--TGACRCPPGVSGTNCEDGC 598
Query: 1387 TEGKYGIHCDQACSCVH-GRCNQ-------------------------GP---------- 1410
+G YG HC + C+C + GRC++ GP
Sbjct: 599 PKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQ 658
Query: 1411 -------LGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC-----LTNSDGTASCKC 1458
DGSC C G+RG C C + C + G +C
Sbjct: 659 PHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRC 718
Query: 1459 AAGFQGN--GTIC-------TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD-- 1507
AGFQG G C ++C C R PGR C+A
Sbjct: 719 PAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRW 778
Query: 1508 GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCS 1567
G+ C EI P ++ CD P AC CLP + G C + C
Sbjct: 779 GLGCQEICPACQHAARCD---------PETGACLCLPGFVGSR--CQDVCPAGWYGPSCQ 827
Query: 1568 EFAICNHTGQVERT---CTCKPNYIGDGFTCR 1596
C + G C+C P + GF+C+
Sbjct: 828 TRCSCANDGHCHPATGHCSCAPGW--TGFSCQ 857
Score = 86.3 bits (212), Expect = 4e-16
Identities = 88/322 (27%), Positives = 116/322 (36%), Gaps = 62/322 (19%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRC-CPGRWGPDCIEC 112
CP+G+ +G ++C +VR GC + D RC CP W D +
Sbjct: 1063 CPEGW----AGLACEKEC-LPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQS 1117
Query: 113 P---GGAGSPCNGRGSCAEGMEGN---GTCSCQEGFGGTACETCADDNLFGPSCSSVCNC 166
P G G C R SC G + G C C GF G+ CE FG C+ +C C
Sbjct: 1118 PCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQC 1177
Query: 167 VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPE------CAALL-CPENSRCSPSTEDENK 219
G + GTC C + Y GP C + P C L C C +T
Sbjct: 1178 -PGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATG---- 1232
Query: 220 LECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPN-RHSCTCQEGYRGDGQVCLPV 278
C+C + G C+ P R GPN H C C G G C PV
Sbjct: 1233 -ACRCPTGFLGTD--CNLTCPQGR-----------FGPNCTHVCGC-----GQGAACDPV 1273
Query: 279 DPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANC 338
T + +C PG++ C+ GVGC T C++ CH +
Sbjct: 1274 -----------TGTCLCP---PGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS 1319
Query: 339 TTVAPGRT----ECICQKGYVG 356
+ G T E C G G
Sbjct: 1320 CSCGLGWTGRHCELACPPGRYG 1341
Score = 85.5 bits (210), Expect = 6e-16
Identities = 87/321 (27%), Positives = 115/321 (35%), Gaps = 58/321 (18%)
Query: 1875 YGIDCL-LIDPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRN 1933
+G+DC + T G CD GSC+ CP + + C +
Sbjct: 952 FGLDCRSACNCTAGAACDAVN--------GSCL----CPAGRRGPRCAETCPAHTYGHNC 999
Query: 1934 LEGCR----ERCSLVIQIPRCCKGYFGRDC-QACPGG-------PDAPCNNRGVCLDQYS 1981
+ C C V C G+ G C QACP G C N G C
Sbjct: 1000 SQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC---DP 1056
Query: 1982 ATGECKCNTGFNGTACEM-CWPGRFGPDCLPCG-CSDHGQCDDGITGSGQCLCETGWTGP 2039
+G C C G+ G ACE C P C G C + G CD +G+CLC GWTG
Sbjct: 1057 VSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPH---TGRCLCPAGWTGD 1113
Query: 2040 SCDTQAV---LPAVCTPPCSA--HATCKE-NNTCECNLDYEGDGI--TCTVVDFCKQDNG 2091
C + + C CS A C C C + G G C F +
Sbjct: 1114 KCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGED--- 1170
Query: 2092 GCAKVARCSQKGTKV-----SCSCQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTG 2145
CA++ +C + +CSC GY G SC + C G G GC + C G
Sbjct: 1171 -CAQMCQCPGENPACHPATGTCSCAAGYHGP--SCQQ--RCPPGRYGPGCEQLCGCLNGG 1225
Query: 2146 ---PGKHKCECKSHYVGDGLN 2163
C C + ++G N
Sbjct: 1226 SCDAATGACRCPTGFLGTDCN 1246
Score = 84.0 bits (206), Expect = 2e-15
Identities = 78/295 (26%), Positives = 103/295 (34%), Gaps = 50/295 (16%)
Query: 97 QPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLF 156
Q RC PGR+GP C + G C GSC G C C GF GT C F
Sbjct: 1203 QQRCPPGRYGPGCEQLCG-----CLNGGSCDAA---TGACRCPTGFLGTDCNLTCPQGRF 1254
Query: 157 GPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPE------CA-ALLCPENSR 209
GP+C+ VC C G + GTC C G +C++ P+ C C
Sbjct: 1255 GPNCTHVCGCGQGAACDPV--TGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1312
Query: 210 CSPSTEDENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAHC---TYLGPNRHSCTC 264
C S C C G++C+ P R CH C + P +C C
Sbjct: 1313 CHASNG-----SCSC--GLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRC 1365
Query: 265 QEGYRGDGQVCLPVDPCQINFGNCPTKSTV-CKYDGP-----GQSHCE-------CKEHY 311
G+ GQ C PC F + C++ P G+ C C+
Sbjct: 1366 GPGFY--GQAC--EHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC 1421
Query: 312 QNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECI----CQKGYVGDGLTCY 362
+ G GC C PC PGR+ C++G G T +
Sbjct: 1422 EPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLH 1476
Score = 77.8 bits (190), Expect = 1e-13
Identities = 87/355 (24%), Positives = 123/355 (34%), Gaps = 98/355 (27%)
Query: 718 YCNATVKIPKCCKGFYG-PDCNQCPGG--FSNPCSGNGQCADSLGGNGTCICEEGFQGSQ 774
Y + +CC+G+ PD C ++ C G+C G C C GFQG +
Sbjct: 100 YTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVP--GSAQPCHCPPGFQGPR 157
Query: 775 CQFCSDP-NKYGPRCNKKCLCVHG-----------------TC---NNRIDSDGAC---- 809
CQ+ D + C +C+ G TC N+ +G C
Sbjct: 158 CQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHC 217
Query: 810 --LTGT-----CRDG----SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY 858
LT T CR G GR C +++ H C+ G A C C GY
Sbjct: 218 VQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMH---RCQVVRGLARCECHVGY 274
Query: 859 E--GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT--GNGRDC----SE 910
+ DG C ++D C G ++ A G+ CVC G+ +GR C E
Sbjct: 275 QLAADGKACEDVDECA----AGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEME 330
Query: 911 INNCLLPSAGGCH----------------------DNASCLYV---------------GP 933
I N + GGC D +C+ V P
Sbjct: 331 IVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNP 390
Query: 934 GQNECECKKGFR--GNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
G EC C G+R +G CE + C G C + +G + C C+ GY
Sbjct: 391 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHC---TNLAGSFQCSCEAGY 442
Score = 77.8 bits (190), Expect = 1e-13
Identities = 110/420 (26%), Positives = 142/420 (33%), Gaps = 96/420 (22%)
Query: 1935 EGCRE--RCSLVIQIPRCCKGYFGRDC-QACPGGPDA---------PCNNRGVCLDQYSA 1982
+ CR C L + C +G+ G C + CP PD C N G C S
Sbjct: 525 DDCRNGGTCLLGLDGCDCPEGWTGLICNETCP--PDTFGKNCSFSCSCQNGGTC---DSV 579
Query: 1983 TGECKCNTGFNGTACE-MCWPGRFGPDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPS 2040
TG C+C G +GT CE C G +G C C C++ G+C G CLC+ G G
Sbjct: 580 TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCH---RLYGACLCDPGLYGRF 636
Query: 2041 CDTQAVLPAVCTPPCSAHATC---------KENNTC-------------ECNLDYEGDG- 2077
C P P CS C K + +C EC L Y G G
Sbjct: 637 CHLTCP-PWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGC 695
Query: 2078 ---ITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGG 2134
TC V C +G C K +G C G G +C+ C G
Sbjct: 696 WQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVG--TFGVNCSSSCSCGGAPCHG 753
Query: 2135 CHEHATCKMTGPGK--HKCECKSHYVGDGLNCE---PEQLPIDRCLQDNGQCHADAKCVD 2189
C PG+ CE GL C+ P RC + G C V
Sbjct: 754 VTGQCRCP---PGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG 810
Query: 2190 LHFQDTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWL 2249
QD P G Y + + R +CAN+ S C+ GW
Sbjct: 811 SRCQDV--------CPAGWYGPSC-QTRCSCANDGHCHPATGHCS---------CAPGW- 851
Query: 2250 ETGRVAYPTAFASQN-CGSGVVGIVDYGP---RPNKSEMWDVFCYRMKDVNCTCKVGYVG 2305
T F+ Q C +G +GP P C + + C C+ GYVG
Sbjct: 852 --------TGFSCQRACDTG-----HWGPDCSHPCNCSAGHGSCDAISGL-CLCEAGYVG 897
Score = 77.4 bits (189), Expect = 2e-13
Identities = 78/286 (27%), Positives = 97/286 (33%), Gaps = 37/286 (12%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQP-CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
C P +C G +G CQ CP C C TG C C GF G+
Sbjct: 760 CPPGRTGEDCEADCPEGRWGLGCQEICPA-----CQHAARCDPE---TGACLCLPGFVGS 811
Query: 1382 ACE-TCTEGKYGIHCDQACSCVH-GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
C+ C G YG C CSC + G C+ G C C GW G C A +
Sbjct: 812 RCQDVCPAGWYGPSCQTRCSCANDGHCHPAT---GHCSCAPGWTGFSCQRACDTGHWGPD 868
Query: 1440 CHTSANCLTNSDG----TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGR 1495
C NC + C C AG+ G C GC + C+
Sbjct: 869 CSHPCNCSAGHGSCDAISGLCLCEAGYV--GPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
Query: 1496 RV---CTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAAC-----NCLPAYT 1547
V CTC AG+ G C + C G D + C T AAC +CL
Sbjct: 927 HVSGACTCPAGWR--GTFC--EHACPAGFFGLDCRSACNCTA--GAACDAVNGSCLCPAG 980
Query: 1548 GDGKVCTLINVCLTKNGGCSEFAICNHTGQ---VERTCTCKPNYIG 1590
G C T CS+ C + V C C P ++G
Sbjct: 981 RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMG 1026
Score = 76.6 bits (187), Expect = 3e-13
Identities = 95/356 (26%), Positives = 123/356 (34%), Gaps = 77/356 (21%)
Query: 39 IRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQP 98
+ EC + G +C G G + R ++V GC+H C
Sbjct: 124 LSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNT---- 179
Query: 99 RCCPGRWGPDCIECPGGA-----GSPCNGRGSCAEGMEG-----------NGTCSCQEGF 142
PG + EC G C SCA G G C C+ GF
Sbjct: 180 ---PGSY---LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 233
Query: 143 ----GGTAC---ETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYT----GPK 191
G C CA+ N SC C V G+ CEC+ Y G
Sbjct: 234 QLQEDGRHCVRRSPCANRN---GSCMHRCQVVRGLAR--------CECHVGYQLAADGKA 282
Query: 192 CDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYR--GDGKYCDPINPCLRKIC--- 246
C+ + ECAA L C + +C C Y DG+ C I + C
Sbjct: 283 CED-VDECAAGLAQCAHGC---LNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAN 338
Query: 247 -----HPHAHCTYLGPNRHSCTCQEGYR--GDGQVCLPVDPCQINFGNCPTKSTVCKYDG 299
H +H T GP CTC GY D + C+ VD C + P VC +
Sbjct: 339 NGGCSHGCSH-TSAGP---LCTCPRGYELDTDQRTCIDVDDC----ADSPCCQQVCT-NN 389
Query: 300 PGQSHCECKEHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGY 354
PG C C Y+ G GC D C S C +CT +A G +C C+ GY
Sbjct: 390 PGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEH--HCTNLA-GSFQCSCEAGY 442
Score = 75.9 bits (185), Expect = 5e-13
Identities = 82/307 (26%), Positives = 118/307 (38%), Gaps = 48/307 (15%)
Query: 1903 GSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEG-CRERCSLVIQIPRC-CKGYFG--RD 1958
G CV + P P +C Y++ R G C+ RC C CK F D
Sbjct: 137 GRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTD 196
Query: 1959 CQACPGGPDAPCNNRGV---CLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCS 2015
+ C N G C+ C+C GF ++ GR PC +
Sbjct: 197 SRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF-----QLQEDGRHCVRRSPCA-N 250
Query: 2016 DHGQCDDG---ITGSGQCLCETGWT----GPSC---DTQAVLPAVCTPPCSAHATCKENN 2065
+G C + G +C C G+ G +C D A A C C + +
Sbjct: 251 RNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGC---LNTQGSF 307
Query: 2066 TCECNLDYE--GDGITC-----TVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--G 2116
C C+ YE DG C +V+ C+ +NGGC+ CS C+C +GY+
Sbjct: 308 KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSH--GCSHTSAGPLCTCPRGYELDT 365
Query: 2117 DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHY--VGDGLNCEPEQLPIDRC 2174
D +C ++D CAD + C + T PG ++C C + Y DG CE +D C
Sbjct: 366 DQRTCIDVDDCAD--SPCCQQVCT---NNPGGYECGCYAGYRLSADGCGCE----DVDEC 416
Query: 2175 LQDNGQC 2181
G C
Sbjct: 417 ASSRGGC 423
Score = 75.9 bits (185), Expect = 5e-13
Identities = 72/293 (24%), Positives = 96/293 (32%), Gaps = 52/293 (17%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQP---CPGNAQNVCFGNGICLDGVNGTGVCECGEGFS 1379
C P + + C G FG C CPG N C TG C C G+
Sbjct: 1149 CPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE-------NPACHPA---TGTCSCAAGYH 1198
Query: 1380 GTACET-CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTE----D 1434
G +C+ C G+YG C+Q C C++G G+C C G+ G C+ +
Sbjct: 1199 GPSCQQRCPPGRYGPGCEQLCGCLNG--GSCDAATGACRCPTGFLGTDCNLTCPQGRFGP 1256
Query: 1435 NCNGTC---------HTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG-CSA 1484
NC C + CL G A +C G N + C NGG C A
Sbjct: 1257 NCTHVCGCGQGAACDPVTGTCLC-PPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHA 1315
Query: 1485 KADCKRTTPGRRVCTCKAGYTGD--GIVCL--EINPCLENHGGCDKNAECTQTGPNQAAC 1540
C+C G+TG + C C N+ C P C
Sbjct: 1316 ---------SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCE---PATGTC 1363
Query: 1541 NCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNH---TGQVERTCTCKPNYIG 1590
C P + G+ C GC C H + C C + G
Sbjct: 1364 RCGPGFY--GQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHG 1414
Score = 75.9 bits (185), Expect = 5e-13
Identities = 70/269 (26%), Positives = 97/269 (36%), Gaps = 71/269 (26%)
Query: 100 CCPGRWGPDCIE---CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLF 156
C PG +G DC + CPG C+ GTCSC G+ G +C+ +
Sbjct: 1162 CPPGSFGEDCAQMCQCPG-ENPACH---------PATGTCSCAAGYHGPSCQQRCPPGRY 1211
Query: 157 GPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTE 215
GP C +C C++ G C++ G C C + + G C+ L CP+ R P+
Sbjct: 1212 GPGCEQLCGCLNGGSCDA---ATGACRCPTGFLGTDCN--------LTCPQ-GRFGPNCT 1259
Query: 216 DENKLECKCLPNYRGDGKYCDPI-NPCLRKICHPHAHCTYLGPN-------RHSCTCQEG 267
C C G G CDP+ CL C P H+C+C+ G
Sbjct: 1260 H----VCGC-----GQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNG 1310
Query: 268 YRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICK 327
C + G+C C G+ HCE PG C
Sbjct: 1311 -----------GLCHASNGSCS-----CGLGWTGR-HCELA-----CPPG---RYGAACH 1345
Query: 328 SDNPCHRNANCTTVAPGRTECICQKGYVG 356
+ CH N+ C P C C G+ G
Sbjct: 1346 LECSCHNNSTC---EPATGTCRCGPGFYG 1371
Score = 75.5 bits (184), Expect = 6e-13
Identities = 79/292 (27%), Positives = 108/292 (36%), Gaps = 54/292 (18%)
Query: 100 CCPGRWGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC-ETCADDNLFG 157
C +G DC + C C G+C G++G C C EG+ G C ETC D FG
Sbjct: 511 CLDDSFGHDCSLTC-----DDCRNGGTCLLGLDG---CDCPEGWTGLICNETCPPDT-FG 561
Query: 158 PSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKCDKPIPE------CAALL-CPENSR 209
+CS C+C + G C+S G C C +G C+ P+ C C R
Sbjct: 562 KNCSFSCSCQNGGTCDS---VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGR 618
Query: 210 CSPSTEDENKLECKCLPNYRGDGKYCDPINP-------CLRKICHPHAHCTYLGPNRHSC 262
C ++L CL + G++C P C + H SC
Sbjct: 619 C-------HRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSC 671
Query: 263 TCQEGYRGD-----------GQVCLPVDPCQINFGNCPTKSTVCKYDGP-GQSHCECKEH 310
+C+ G+RG+ G C C + C + S C P G +C +
Sbjct: 672 SCKAGFRGERCQAECELGYFGPGCWQACTCPVGVA-CDSVSGECGKRCPAGFQGEDCGQE 730
Query: 311 YQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRT----ECICQKGYVGDG 358
GV CS + C PCH PGRT E C +G G G
Sbjct: 731 CPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLG 781
Score = 72.4 bits (176), Expect = 5e-12
Identities = 83/304 (27%), Positives = 113/304 (37%), Gaps = 58/304 (19%)
Query: 1905 CVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGCRERC-SLVIQIPRC-CKGYF-- 1955
CVNTP C + + CL GC+ C L I RC C+ F
Sbjct: 176 CVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQL 235
Query: 1956 ---GRDCQACPGGPDAPCNNR-GVCLDQYSAT---GECKCNTGF----NGTACEMCWPGR 2004
GR C +PC NR G C+ + C+C+ G+ +G ACE
Sbjct: 236 QEDGRHCVR-----RSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE------ 284
Query: 2005 FGPDCLPCGCSDHGQCDDGIT---GSGQCLCETGWT----GPSC--------DTQAVLPA 2049
D C QC G GS +C+C G+ G C ++
Sbjct: 285 ---DVDECAAG-LAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNG 340
Query: 2050 VCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCS 2109
C+ CS H + TC + + D TC VD C D+ C +V C+ C
Sbjct: 341 GCSHGCS-HTSAGPLCTCPRGYELDTDQRTCIDVDDCA-DSPCCQQV--CTNNPGGYECG 396
Query: 2110 CQKGYK--GDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPE 2167
C GY+ DG C ++D CA GGC H T + G + CE D C P
Sbjct: 397 CYAGYRLSADGCGCEDVDECASS-RGGCEHHCT-NLAGSFQCSCEAGYRLHEDRRGCSPL 454
Query: 2168 QLPI 2171
+ P+
Sbjct: 455 EEPM 458
Score = 70.9 bits (172), Expect = 2e-11
Identities = 76/313 (24%), Positives = 108/313 (34%), Gaps = 71/313 (22%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTAC-ETCTEGKYGIH 1394
C FG C + +N G CL G++G C+C EG++G C ETC +G +
Sbjct: 511 CLDDSFGHDCSLTCDDCRN----GGTCLLGLDG---CDCPEGWTGLICNETCPPDTFGKN 563
Query: 1395 CDQACSCVH-GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG- 1452
C +CSC + G C+ G+C C G G +C++ + C NC
Sbjct: 564 CSFSCSCQNGGTCDS---VTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCH 620
Query: 1453 --TASCKCAAGFQGN-----------GTICTA--------INACEISNGGCSAKADCKRT 1491
+C C G G G C+ +C+ +G CS KA +
Sbjct: 621 RLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGE 680
Query: 1492 TPGRRVCTCKAGYTGDG----IVCLEINPCLENHGGCDKNA-------ECTQTGP-NQAA 1539
R C+ GY G G C C G C K +C Q P
Sbjct: 681 ---RCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFG 737
Query: 1540 CNCLPAYTGDGKVC-TLINVCLTKNG-----------------GCSEFA-ICNHTGQVE- 1579
NC + + G C + C G GC E C H + +
Sbjct: 738 VNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDP 797
Query: 1580 --RTCTCKPNYIG 1590
C C P ++G
Sbjct: 798 ETGACLCLPGFVG 810
Score = 66.2 bits (160), Expect = 4e-10
Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 15/129 (11%)
Query: 1949 RCCKGYFGRDCQ-ACPGG-PDAPCNNRGVCLDQYSA-----TGECKCNTGFNGTACEM-C 2000
RC G++G+ C+ CP G A C +G+C Q+ A +G C C GF+G CE C
Sbjct: 1364 RCGPGFYGQACEHPCPPGFHGAGC--QGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC 1421
Query: 2001 WPGRFGPDCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHA 2059
PG FG C C C CD +G CLC G +G +C+ P C+ H
Sbjct: 1422 EPGSFGEGCHQRCDCDGGAPCDPV---TGLCLCPPGRSGATCNLDC-RRGQFGPSCTLHC 1477
Query: 2060 TCKENNTCE 2068
C C+
Sbjct: 1478 DCGGGADCD 1486
Score = 65.9 bits (159), Expect = 5e-10
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 35/251 (13%)
Query: 1949 RCCKGYFGR-DCQACPGGPDAP--CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
RCC+G+ + D + C + C + G C+ + C C GF G C+
Sbjct: 109 RCCRGWMQQPDEEGCLSAECSASLCFHGGRCVP--GSAQPCHCPPGFQGPRCQY------ 160
Query: 2006 GPDCLPCGCSDHGQCDD---GITGSGQCLCETGW-------TGPSCDTQAVLPAVCTPPC 2055
D C + +G C GS C C+ G+ T + ++ A+ C C
Sbjct: 161 --DVDECR-THNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHC 217
Query: 2056 SAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK 2115
+ C + DG C C NG C + RC C C GY+
Sbjct: 218 VQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSC--MHRCQVVRGLARCECHVGYQ 275
Query: 2116 --GDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYV--GDGLNCEPEQLPI 2171
DG +C ++D CA GL H C T G KC C + Y DG C ++ I
Sbjct: 276 LAADGKACEDVDECAAGLAQCAH---GCLNT-QGSFKCVCHAGYELGADGRQCYRIEMEI 331
Query: 2172 -DRCLQDNGQC 2181
+ C +NG C
Sbjct: 332 VNSCEANNGGC 342
Score = 64.7 bits (156), Expect = 1e-09
Identities = 52/181 (28%), Positives = 73/181 (40%), Gaps = 26/181 (14%)
Query: 706 GRFGS---LKSGCARY--CNATVKIPKCCKGFYGPDCNQ-CPGGFSNP-CSG-----NGQ 753
GR+G+ L+ C C +C GFYG C CP GF C G +G
Sbjct: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGA 1397
Query: 754 CADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGT 813
D + G C+C GF G C+ +P +G C+++C C G + + G CL
Sbjct: 1398 PCDPISGR--CLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPV--TGLCL--- 1450
Query: 814 CRDGSAGRLCDKQTSACGPYVQFCHIHATC----EYSNGTASCICKAGYEGDGTLCSEMD 869
C G +G C+ G + C +H C + + C C GY G C E
Sbjct: 1451 CPPGRSGATCNLDCRR-GQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYM--GPTCREGG 1507
Query: 870 P 870
P
Sbjct: 1508 P 1508
Score = 61.6 bits (148), Expect = 9e-09
Identities = 37/95 (38%), Positives = 43/95 (45%), Gaps = 15/95 (15%)
Query: 1950 CCKGYFGRDC-QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM-CWPGRFGP 2007
C G FG C Q C APC+ TG C C G +G C + C G+FGP
Sbjct: 1421 CEPGSFGEGCHQRCDCDGGAPCD---------PVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Query: 2008 DC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSC 2041
C L C C CD SGQC C G+ GP+C
Sbjct: 1472 SCTLHCDCGGGADCDPV---SGQCHCVDGYMGPTC 1503
Score = 58.5 bits (140), Expect = 8e-08
Identities = 46/131 (35%), Positives = 53/131 (40%), Gaps = 19/131 (14%)
Query: 87 CRHICRKDYLQPRC-CP-GRWGPDCIE-C-PGGAGSPCNGRGSCAEGMEGN---GTCSCQ 139
C+H D + RC CP G G C C PG G C+ R C G + G C C
Sbjct: 1393 CQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCP 1452
Query: 140 EGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGD---GTCECYSAYTGPKCDKPI 196
G G C FGPSC+ C+ C G D D G C C Y GP C +
Sbjct: 1453 PGRSGATCNLDCRRGQFGPSCTLHCD-----CGGGADCDPVSGQCHCVDGYMGPTCREGG 1507
Query: 197 PECAALLCPEN 207
P L PEN
Sbjct: 1508 P----LRLPEN 1514
Score = 53.1 bits (126), Expect = 3e-06
Identities = 52/191 (27%), Positives = 70/191 (36%), Gaps = 34/191 (17%)
Query: 1999 MCWPGRFGPDC-LPCG-CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCS 2056
+C FG DC L C C + G C G+ G C C GWTG C+ + P CS
Sbjct: 510 VCLDDSFGHDCSLTCDDCRNGGTCLLGLDG---CDCPEGWTGLICN-ETCPPDTFGKNCS 565
Query: 2057 AHATCKENNTCE-----CNLDYEGDGITCTVVDFCKQDNGG--CAKVARCSQKG----TK 2105
+C+ TC+ C G C D C + G C K C+ +G
Sbjct: 566 FSCSCQNGGTCDSVTGACRCPPGVSGTNCE--DGCPKGYYGKHCRKKCNCANRGRCHRLY 623
Query: 2106 VSCSCQKGYKGD-----------GHSCTEIDPCADGLNGGCHEH---ATCKMTGPGKH-K 2150
+C C G G G C+E C C + +CK G+ +
Sbjct: 624 GACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQ 683
Query: 2151 CECKSHYVGDG 2161
EC+ Y G G
Sbjct: 684 AECELGYFGPG 694
Score = 40.4 bits (93), Expect = 0.023
Identities = 41/157 (26%), Positives = 56/157 (35%), Gaps = 25/157 (15%)
Query: 1323 CQPKCVRTVITRECCA------GFFGPQCQPCPGNAQNVC-FGNGICLDGVNGTG---VC 1372
C C+ T + +C G G QC N C NG C G + T +C
Sbjct: 296 CAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC 355
Query: 1373 ECGEGFSGTACETCTEGKYGIHCDQACS--CVHGRCNQGPLGDGSCDCDVGWR----GVH 1426
C G+ E T+ + I D C C P G C C G+R G
Sbjct: 356 TCPRGY-----ELDTDQRTCIDVDDCADSPCCQQVCTNNP-GGYECGCYAGYRLSADGCG 409
Query: 1427 CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
C++ + G C TN G+ C C AG++
Sbjct: 410 CEDVDECASSRGGCEHHC---TNLAGSFQCSCEAGYR 443
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 109 bits (272), Expect = 4e-23
Identities = 93/323 (28%), Positives = 118/323 (36%), Gaps = 49/323 (15%)
Query: 1285 RTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQ 1344
+ CS + C G + + +C T+ +MG R CQ EC G FG Q
Sbjct: 269 QNCSQDCPCHHGGQC-DHVTGQCHCTAGYMGDR-----CQ---------EECPFGSFGFQ 313
Query: 1345 C-QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET--CTEGKYGIHCDQACSC 1401
C Q C C G C TG CEC G+ G C+ C EG +G C C C
Sbjct: 314 CSQHCD------CHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPC 364
Query: 1402 VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG---TASCKC 1458
G+C C GW G HC+ + C C +D T C C
Sbjct: 365 DADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTC 424
Query: 1459 AAGFQGNGTICTAINACEISNGGCSAKADCKR---TTPGRRVCTCKAGYTGDGIVCLEIN 1515
A GF G +C A CS+ C +P CTCK G+ G+ C
Sbjct: 425 APGFMGE--VCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGW--QGLDC--TL 478
Query: 1516 PCLENHGGCDKNAECT-----QTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1570
PC G + N CT P +C+C P + GD C L T CSE
Sbjct: 479 PCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD--TCELPCPDGTFGLNCSEHC 536
Query: 1571 ICNHT---GQVERTCTCKPNYIG 1590
C+H V C C + G
Sbjct: 537 DCSHADGCDPVTGHCCCLAGWTG 559
Score = 105 bits (263), Expect = 4e-22
Identities = 89/287 (31%), Positives = 115/287 (40%), Gaps = 39/287 (13%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTA 1382
CQP C G++G CQ P QN + I TG C C GF G
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQ-LPCTCQNGADCHSI-------TGGCTCAPGFMGEV 432
Query: 1383 CE-TCTEGKYGIHCDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVH----CDNATTEDNC 1436
C +C G YG +C CSC +G C+ P+ DGSC C GW+G+ C + T NC
Sbjct: 433 CAVSCAAGTYGPNCSSICSCNNGGTCS--PV-DGSCTCKEGWQGLDCTLPCPSGTWGLNC 489
Query: 1437 NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG--CSAKADCKRT--- 1491
N +C T AN S SC C G+ G+ T C G CS DC
Sbjct: 490 NESC-TCANGAACSPIDGSCSCTPGWLGD----TCELPCPDGTFGLNCSEHCDCSHADGC 544
Query: 1492 TPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG---PNQAACNCLPAYTG 1548
P C C AG+T GI C P C + C G P +C C P +
Sbjct: 545 DPVTGHCCCLAGWT--GIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFR- 601
Query: 1549 DGKVCTLINVCLTKNGGCSE-FAICNHTGQ----VERTCTCKPNYIG 1590
G +C I GC++ +C H+ + + C C P + G
Sbjct: 602 -GPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSG 647
Score = 102 bits (253), Expect = 6e-21
Identities = 86/296 (29%), Positives = 119/296 (40%), Gaps = 48/296 (16%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQC-QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
C P V + C G FG C Q CP C G C D V TG C C G+ G
Sbjct: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCP------CHHGGQC-DHV--TGQCHCTAGYMGD 299
Query: 1382 AC-ETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT- 1439
C E C G +G C Q C C +G Q G+C+C+ G++G C + +G
Sbjct: 300 RCQEECPFGSFGFQCSQHCDCHNG--GQCSPTTGACECEPGYKGPRCQERLCPEGLHGPG 357
Query: 1440 ----CHTSA-NCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG--------CSAKA 1486
C A N ++ T +C C G+ G+ C +C + G C A
Sbjct: 358 CTLPCPCDADNTISCHPVTGACTCQPGWSGHH--CN--ESCPVGYYGDGCQLPCTCQNGA 413
Query: 1487 DCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHG-GCDKNAECTQTG---PNQAACNC 1542
DC T G CTC G+ G+ VC ++ +G C C G P +C C
Sbjct: 414 DCHSITGG---CTCAPGFMGE--VCA-VSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTC 467
Query: 1543 LPAYTGDGKVCTLINVCLTKNGGCSEFAICNH---TGQVERTCTCKPNYIGDGFTC 1595
+ G CTL T C+E C + ++ +C+C P ++GD TC
Sbjct: 468 KEGW--QGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD--TC 519
Score = 96.7 bits (239), Expect = 3e-19
Identities = 89/308 (28%), Positives = 117/308 (37%), Gaps = 57/308 (18%)
Query: 719 CNATVKIPKCCKGFYGPDCNQ-CPGGFSNP-------CSGNGQCADSLGGNGTCICEEGF 770
C+ C G+ G CN+ CP G+ C C GG C C GF
Sbjct: 372 CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG---CTCAPGF 428
Query: 771 QGSQCQFCSDPNKYGPRCNKKCLCVH-GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA 829
G C YGP C+ C C + GTC+ DG+C TC++G G C T
Sbjct: 429 MGEVCAVSCAAGTYGPNCSSICSCNNGGTCS---PVDGSC---TCKEGWQGLDC---TLP 479
Query: 830 CGPYVQFCHIHATCEYSNGTA------SCICKAGYEGDGTLCSEMDPCTGLTPG-GCSRN 882
C + + +C +NG A SC C G+ GD C PC T G CS +
Sbjct: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD--TCEL--PCPDGTFGLNCSEH 535
Query: 883 AECIKT---GTGTHTCVCQQGWTGNGRDCSEINNCLLPSAG---GCHDNASCLYVGPGQN 936
+C T C C GWTG D + P+ C + SC P
Sbjct: 536 CDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSC---SPEDG 592
Query: 937 ECECKKGFRG-----------NGIDC-EPITSCLEQTGKCHPLAS-CQ---STSSGVWSC 980
CEC GFRG G C +P C+ + CH ++ C+ S + +
Sbjct: 593 SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQ 652
Query: 981 VCQEGYEG 988
VC GY G
Sbjct: 653 VCAGGYFG 660
Score = 96.3 bits (238), Expect = 3e-19
Identities = 82/288 (28%), Positives = 114/288 (39%), Gaps = 59/288 (20%)
Query: 727 KCCKGFYGPDCNQCPGGFSNP-CSG---NGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
+CC G+Y G F P C+ +G+C TC CE G+ G C D +
Sbjct: 87 QCCPGYYES------GDFCIPLCTEECVHGRCVSP----DTCHCEPGWGGPDCSSGCDSD 136
Query: 783 KYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHAT 842
+GP C+ +C C +G N I GAC+ C G G C+ + A G + + C +
Sbjct: 137 HWGPHCSNRCQCQNGALCNPI--TGACV---CAAGFRGWRCE-ELCAPGTHGKGCQLPCQ 190
Query: 843 CEYSNG----TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTH---TC 895
C + C+C GY G C E+ P G C C GT H C
Sbjct: 191 CRHGASCDPRAGECLCAPGY--TGVYCEELCP-PGSHGAHCELRCPCQNGGTCHHITGEC 247
Query: 896 VCQQGWTGN-----------GRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF 944
C GWTG G++CS+ +C CH C +V +C C G+
Sbjct: 248 ACPPGWTGAVCAQPCPPGTFGQNCSQ--DC------PCHHGGQCDHV---TGQCHCTAGY 296
Query: 945 RGNGIDCE-PITSC---LEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
G+ E P S Q CH C T+ +C C+ GY+G
Sbjct: 297 MGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTG---ACECEPGYKG 341
Score = 95.9 bits (237), Expect = 5e-19
Identities = 88/322 (27%), Positives = 112/322 (34%), Gaps = 78/322 (24%)
Query: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVN---GTGVCECGEGFSGTACET-CTEG 1389
C AGF G +C+ PG C C G + G C C G++G CE C G
Sbjct: 163 CAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPG 222
Query: 1390 KYGIHCDQACSCVH-GRCNQGPLGDGSCDCDVGWRGV----HCDNATTEDNCNG--TCHT 1442
+G HC+ C C + G C+ G C C GW G C T NC+ CH
Sbjct: 223 SHGAHCELRCPCQNGGTCHH---ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHH 279
Query: 1443 SANCLTNSDGTASCKCAAGFQG-----------------------NGTICT-AINACEIS 1478
C T C C AG+ G NG C+ ACE
Sbjct: 280 GGQC---DHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
Query: 1479 NG------------------GCSAKADCKRTT-----PGRRVCTCKAGYTGDGIVCLEIN 1515
G GC+ C P CTC+ G++G C E
Sbjct: 337 PGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH--CNESC 394
Query: 1516 PCLENHGGCDKNAECTQTGPN----QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAI 1571
P GC C Q G + C C P + G+ VC + T CS
Sbjct: 395 PVGYYGDGCQLPCTC-QNGADCHSITGGCTCAPGFMGE--VCAVSCAAGTYGPNCSSICS 451
Query: 1572 CNHTG---QVERTCTCKPNYIG 1590
CN+ G V+ +CTCK + G
Sbjct: 452 CNNGGTCSPVDGSCTCKEGWQG 473
Score = 93.6 bits (231), Expect = 2e-18
Identities = 72/246 (29%), Positives = 99/246 (40%), Gaps = 42/246 (17%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQC-QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
C P + R C GF+G C QPCP +C + ++G +CEC GFSG
Sbjct: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCP-----LCVHSSRPCHHISG--ICECLPGFSGA 648
Query: 1382 AC-ETCTEGKYGIHCDQACSCV-HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
C + C G +G C Q CSC +G C+ P+ DGSC C GW G C A
Sbjct: 649 LCNQVCAGGYFGQDCAQLCSCANNGTCS--PI-DGSCQCFPGWIGKDCSQACPPGFWGPA 705
Query: 1440 CHTSANCLTNSDGTA---SCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRR 1496
C + +C + +A +C C G+ G CT C C+
Sbjct: 706 CFHACSCHNGASCSAEDGACHCTPGW--TGLFCTQRCPAAFFGKDCGRVCQCQNGASCDH 763
Query: 1497 V---CTCKAGYTGD-----------GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC 1542
+ CTC+ G+TG G C ++ C+ N+ CD TG C C
Sbjct: 764 ISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECM-NNSTCDH-----VTG----TCYC 813
Query: 1543 LPAYTG 1548
P + G
Sbjct: 814 SPGFKG 819
Score = 93.2 bits (230), Expect = 3e-18
Identities = 83/303 (27%), Positives = 116/303 (38%), Gaps = 52/303 (17%)
Query: 715 CARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQ 774
CA V C G YGP+C+ C+ G C+ +G+C C+EG+QG
Sbjct: 424 CAPGFMGEVCAVSCAAGTYGPNCSSICS-----CNNGGTCSPV---DGSCTCKEGWQGLD 475
Query: 775 CQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
C +G CN+ C C +G + I DG+C +C G G C+ G +
Sbjct: 476 CTLPCPSGTWGLNCNESCTCANGAACSPI--DGSC---SCTPGWLGDTCELPCPD-GTFG 529
Query: 835 QFCHIHATCEYSNG----TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGT 890
C H C +++G T C C AG+ G C P G CS + C G+
Sbjct: 530 LNCSEHCDCSHADGCDPVTGHCCCLAGW--TGIRCDSTCP-PGRWGPNCSVSCSCENGGS 586
Query: 891 GT---HTCVCQQGWTGNGRDCSEI-------NNCLLPSAGGCHDNASCLYVGPGQNECEC 940
+ +C C G+ G C I + C P H + C ++ CEC
Sbjct: 587 CSPEDGSCECAPGF--RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHI---SGICEC 641
Query: 941 KKGFRGN-----------GIDCEPITSCLEQTGKCHPL-ASCQSTSSGV---WSCVCQEG 985
GF G G DC + SC G C P+ SCQ + S C G
Sbjct: 642 LPGFSGALCNQVCAGGYFGQDCAQLCSC-ANNGTCSPIDGSCQCFPGWIGKDCSQACPPG 700
Query: 986 YEG 988
+ G
Sbjct: 701 FWG 703
Score = 92.8 bits (229), Expect = 4e-18
Identities = 103/340 (30%), Positives = 120/340 (35%), Gaps = 85/340 (25%)
Query: 1901 EC--GSCVNTPSC---PRWSKPKGVKQKCLYNLPFKRNLEGCRERCSL--------VIQI 1947
EC G CV+ +C P W P C C RC +
Sbjct: 106 ECVHGRCVSPDTCHCEPGWGGPD-----CSSGCDSDHWGPHCSNRCQCQNGALCNPITGA 160
Query: 1948 PRCCKGYFGRDCQ--ACPG----GPDAPCNNR-GVCLDQYSATGECKCNTGFNGTACE-M 1999
C G+ G C+ PG G PC R G D + GEC C G+ G CE +
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA--GECLCAPGYTGVYCEEL 218
Query: 2000 CWPGRFGPDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAH 2058
C PG G C L C C + G C ITG +C C GWTG C Q P CS
Sbjct: 219 CPPGSHGAHCELRCPCQNGGTCHH-ITG--ECACPPGWTGAVC-AQPCPPGTFGQNCSQD 274
Query: 2059 ATCKENNTCE-------CNLDYEGD-----------GITCTVVDFCKQDNGGCAKVARCS 2100
C C+ C Y GD G C+ C NGG +CS
Sbjct: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS--QHCDCHNGG-----QCS 327
Query: 2101 QKGTKVSCSCQKGYKG------------DGHSCTEIDPCADGLNGGCHE---HATCKMTG 2145
T +C C+ GYKG G CT PC CH TC+
Sbjct: 328 P--TTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGW 385
Query: 2146 PGKHKCE-CKSHYVGDGLNCEPEQLPIDRCLQDNG-QCHA 2183
G H E C Y GDG QLP C NG CH+
Sbjct: 386 SGHHCNESCPVGYYGDGC-----QLP---CTCQNGADCHS 417
Score = 92.0 bits (227), Expect = 7e-18
Identities = 89/315 (28%), Positives = 120/315 (38%), Gaps = 79/315 (25%)
Query: 728 CCKGFYGPDCNQ-CP-GGFSNPCS------GNGQCADSLGGNGTCICEEGFQGSQCQ--F 777
C G+ G C + CP G F CS GQC+ + G C CE G++G +CQ
Sbjct: 292 CTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT---TGACECEPGYKGPRCQERL 348
Query: 778 CSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFC 837
C + +GP C C C + GAC TC+ G +G C+ ++ G Y C
Sbjct: 349 CPE-GLHGPGCTLPCPCDADNTISCHPVTGAC---TCQPGWSGHHCN-ESCPVGYYGDGC 403
Query: 838 HIHATCEYSNG------TASCICKAGYEGDGTLCSEMDPCTGLTPG-GCSRNAECIKTGT 890
+ TC+ NG T C C G+ G+ S C T G CS C GT
Sbjct: 404 QLPCTCQ--NGADCHSITGGCTCAPGFMGEVCAVS----CAAGTYGPNCSSICSCNNGGT 457
Query: 891 GT---HTCVCQQGWTGNGRDCSEINNCLLPSAGG-----CHDNASC---LYVGPGQNECE 939
+ +C C++GW G +C LP G C+++ +C P C
Sbjct: 458 CSPVDGSCTCKEGWQG--------LDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCS 509
Query: 940 CKKGFRGN-----------------GIDCEPITSCLEQTGKCHPLAS-----CQST-SSG 976
C G+ G+ DC C TG C LA C ST G
Sbjct: 510 CTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPG 569
Query: 977 VW------SCVCQEG 985
W SC C+ G
Sbjct: 570 RWGPNCSVSCSCENG 584
Score = 91.7 bits (226), Expect = 9e-18
Identities = 79/286 (27%), Positives = 105/286 (36%), Gaps = 86/286 (30%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTAC-EMCWPGRFGPD 2008
C G FG++C D PC++ G C TG+C C G+ G C E C G FG
Sbjct: 262 CPPGTFGQNCSQ-----DCPCHHGGQC---DHVTGQCHCTAGYMGDRCQEECPFGSFGFQ 313
Query: 2009 CLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTC 2067
C C C + GQC +G C CE G+ GP C + + P C+ C +NT
Sbjct: 314 CSQHCDCHNGGQCSPT---TGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTI 370
Query: 2068 ECN----------------------LDYEGDG----ITCTVVDFCKQDNGG--------- 2092
C+ + Y GDG TC C GG
Sbjct: 371 SCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMG 430
Query: 2093 ---------------CAKVARCSQKGT----KVSCSCQKGYKGDGHSCTEIDPCADGLNG 2133
C+ + C+ GT SC+C++G++ G CT PC G G
Sbjct: 431 EVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQ--GLDCTL--PCPSGTWG 486
Query: 2134 -GCHEHATC---KMTGPGKHKCECKSHYVGD-----------GLNC 2164
C+E TC P C C ++GD GLNC
Sbjct: 487 LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNC 532
Score = 91.3 bits (225), Expect = 1e-17
Identities = 68/223 (30%), Positives = 88/223 (39%), Gaps = 28/223 (12%)
Query: 1386 CTEGKY--GIHCDQACS--CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTED----NCN 1437
C G Y G C C+ CVHGRC + +C C+ GW G C + D +C+
Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRC----VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143
Query: 1438 GTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKR---TTPG 1494
C L N T +C CAAGF+ G C + A GC C+ P
Sbjct: 144 NRCQCQNGALCNPI-TGACVCAAGFR--GWRCEELCAPGTHGKGCQLPCQCRHGASCDPR 200
Query: 1495 RRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQ---AACNCLPAYTGDGK 1551
C C GYT G+ C E+ P + C+ C G C C P +T G
Sbjct: 201 AGECLCAPGYT--GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT--GA 256
Query: 1552 VCTLINVCLTKNGGCSEFAICNHTGQVERT---CTCKPNYIGD 1591
VC T CS+ C+H GQ + C C Y+GD
Sbjct: 257 VCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGD 299
Score = 88.6 bits (218), Expect = 7e-17
Identities = 91/331 (27%), Positives = 119/331 (35%), Gaps = 56/331 (16%)
Query: 1296 GTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVR----TVITRECCAGFFGPQCQP-CPG 1350
G +++ + +C Y G + + C +CV + T C G+ GP C C
Sbjct: 77 GLRTMYRRRSQCCPGYYESGDFCIPL-CTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDS 135
Query: 1351 N-----AQNVC-FGNGICLDGVNGTGVCECGEGFSGTAC-ETCTEGKYGIHCDQACSCVH 1403
+ N C NG + + TG C C GF G C E C G +G C C C H
Sbjct: 136 DHWGPHCSNRCQCQNGALCNPI--TGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRH 193
Query: 1404 G-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCL---TNSDGTASCKCA 1459
G C+ G C C G+ GV+C+ + C C T T C C
Sbjct: 194 GASCDPRA---GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACP 250
Query: 1460 AGFQGNGTICTAINACEISNGGCSAKADCKRTTPGR-----RVCTCKAGYTGDGIVCLEI 1514
G+ G +C C G + DC G+ C C AGY GD C E
Sbjct: 251 PGW--TGAVCA--QPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDR--CQEE 304
Query: 1515 NPCLENHGGCDKNAEC---TQTGPNQAACNCLPAYTG------------DGKVCTLINVC 1559
P C ++ +C Q P AC C P Y G G CTL C
Sbjct: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPC 364
Query: 1560 LTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
N I H V CTC+P + G
Sbjct: 365 DADN------TISCH--PVTGACTCQPGWSG 387
Score = 88.2 bits (217), Expect = 9e-17
Identities = 79/289 (27%), Positives = 109/289 (37%), Gaps = 41/289 (14%)
Query: 100 CCPGRWGPDCIE-CPGGA-GSPCNGRGSCAEGMEGN---GTCSCQEGFGGTACETCADDN 154
C PG G C E CP G G C +C G + + G C+C GF G C
Sbjct: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
Query: 155 LFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP------EC-AALLCPEN 207
+GP+CSS+C+C +G S + DG+C C + G C P P C + C
Sbjct: 441 TYGPNCSSICSCNNGGTCSPV--DGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
Query: 208 SRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTY---LGPNRHSCTC 264
+ CSP C C P + GD + C H C++ P C C
Sbjct: 499 AACSPIDG-----SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCC 553
Query: 265 QEGYRGD-----------GQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQN 313
G+ G G C C+ N G+C + C+ PG C+
Sbjct: 554 LAGWTGIRCDSTCPPGRWGPNCSVSCSCE-NGGSCSPEDGSCEC-APGFRGPLCQRICPP 611
Query: 314 FVPGVGCSM-TDIC-KSDNPCHRNANCTTVAPGRTECICQK----GYVG 356
G GC+ +C S PCH + PG + +C + GY G
Sbjct: 612 GFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG 660
Score = 86.7 bits (213), Expect = 3e-16
Identities = 64/206 (31%), Positives = 88/206 (42%), Gaps = 33/206 (16%)
Query: 716 ARYCNATVKIPKCCKGFYGPDCNQ-CPGGFSNP-------CSGNGQCADSLGGNGTCICE 767
+R C+ I +C GF G CNQ C GG+ C+ NG C+ +G+C C
Sbjct: 629 SRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI---DGSCQCF 685
Query: 768 EGFQGSQCQFCSDPNKYGPRCNKKCLCVHG-TCNNRIDSDGACLTGTCRDGSAGRLCDKQ 826
G+ G C P +GP C C C +G +C+ DGAC C G G C ++
Sbjct: 686 PGWIGKDCSQACPPGFWGPACFHACSCHNGASCS---AEDGAC---HCTPGWTGLFCTQR 739
Query: 827 TSA------CGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCS 880
A CG Q C A+C++ +G C C+ G+ G E G GC
Sbjct: 740 CPAAFFGKDCGRVCQ-CQNGASCDHISG--KCTCRTGFTGQH---CEQRCAPGTFGYGCQ 793
Query: 881 RNAECIKTGTGTH---TCVCQQGWTG 903
+ EC+ T H TC C G+ G
Sbjct: 794 QLCECMNNSTCDHVTGTCYCSPGFKG 819
Score = 82.4 bits (202), Expect = 5e-15
Identities = 98/357 (27%), Positives = 123/357 (34%), Gaps = 110/357 (30%)
Query: 87 CRHICRKDYLQPR-----CCPGRWGPDCIEC--PGGAGSPCNGRGSCAEGMEGN---GTC 136
CRH D PR C PG G C E PG G+ C R C G + G C
Sbjct: 191 CRHGASCD---PRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGEC 247
Query: 137 SCQEGFGGTACETCADDNLFGPSCSSVCNCVHGV----------CNSGLDGD-------- 178
+C G+ G C FG +CS C C HG C +G GD
Sbjct: 248 ACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPF 307
Query: 179 -----------------------GTCECYSAYTGPKCDKPI-------PECAALLCP--- 205
G CEC Y GP+C + + P C L CP
Sbjct: 308 GSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGC-TLPCPCDA 366
Query: 206 -ENSRCSPSTEDENKLECKCLPNYRGD--------GKYCDPIN-PCLRKICHPHAHCTYL 255
C P T C C P + G G Y D PC C A C +
Sbjct: 367 DNTISCHPVTG-----ACTCQPGWSGHHCNESCPVGYYGDGCQLPC---TCQNGADCHSI 418
Query: 256 GPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYD-----GPGQSHCECKEH 310
CTC G+ G+VC V +G P S++C + P C CKE
Sbjct: 419 ---TGGCTCAPGFM--GEVC-AVSCAAGTYG--PNCSSICSCNNGGTCSPVDGSCTCKEG 470
Query: 311 YQNFVPGVGCSMTDICKSDN---PCHRNANCTTVA---PGRTECICQKGYVGDGLTC 361
+Q G+ C++ C S C+ + C A P C C G++GD TC
Sbjct: 471 WQ----GLDCTLP--CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD--TC 519
Score = 81.6 bits (200), Expect = 9e-15
Identities = 92/377 (24%), Positives = 121/377 (32%), Gaps = 114/377 (30%)
Query: 45 SCALNLGVKCP--DGYTMITSGSVGVRDCRYTFEVRTYSLSLP---GCRHICRKDYLQPR 99
SC G C DG T G +G C T+ L+ C H D +
Sbjct: 492 SCTCANGAACSPIDGSCSCTPGWLG-DTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH 550
Query: 100 CC---------------PGRWGPDC-IECP---GGAGSPCNGRGSCAEGMEG-------- 132
CC PGRWGP+C + C GG+ SP +G CA G G
Sbjct: 551 CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICP 610
Query: 133 -------------------------NGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCV 167
+G C C GF G C FG C+ +C+C
Sbjct: 611 PGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 670
Query: 168 -HGVCNSGLDGDGTCECYSAYTGPKCDKPIP-----ECAALLCPENSRCSPSTEDENKLE 221
+G C+ DG+C+C+ + G C + P C ++ S S ED
Sbjct: 671 NNGTCS---PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDG---A 724
Query: 222 CKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPN-RHSCTCQEGYRGDGQVCLPVDP 280
C C P + G C + G + C CQ G
Sbjct: 725 CHCTPGWTG-------------LFCTQRCPAAFFGKDCGRVCQCQNG-----------AS 760
Query: 281 CQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGV-GCSMTDICKSDNPCHRNANCT 339
C G C C+ GQ HCE Q PG G +C+ C N+ C
Sbjct: 761 CDHISGKC-----TCRTGFTGQ-HCE-----QRCAPGTFGYGCQQLCE----CMNNSTCD 805
Query: 340 TVAPGRTECICQKGYVG 356
V C C G+ G
Sbjct: 806 HVT---GTCYCSPGFKG 819
Score = 80.9 bits (198), Expect = 2e-14
Identities = 72/243 (29%), Positives = 99/243 (40%), Gaps = 34/243 (13%)
Query: 1941 CSLVIQIPRCCKGYFGRDCQA-CPGGP-DAPCNNRGVCLDQYSAT---GECKCNTGFNGT 1995
CS V C +G+ G DC CP G CN C + + + G C C G+ G
Sbjct: 458 CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD 517
Query: 1996 ACEM-CWPGRFGPDCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP 2053
CE+ C G FG +C C CS CD +G C C GWTG CD+ P P
Sbjct: 518 TCELPCPDGTFGLNCSEHCDCSHADGCDPV---TGHCCCLAGWTGIRCDSTCP-PGRWGP 573
Query: 2054 PCSAHATCK-------ENNTCECNLDYEGDGITCTVVDFCKQDNGGCAK----VARCSQK 2102
CS +C+ E+ +CEC + G C + GCA+ S+
Sbjct: 574 NCSVSCSCENGGSCSPEDGSCECAPGFRGP--LCQRICPPGFYGHGCAQPCPLCVHSSRP 631
Query: 2103 GTKVS--CSCQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTG---PGKHKCECKSH 2156
+S C C G+ G C ++ CA G G C + +C G P C+C
Sbjct: 632 CHHISGICECLPGF--SGALCNQV--CAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPG 687
Query: 2157 YVG 2159
++G
Sbjct: 688 WIG 690
Score = 80.5 bits (197), Expect = 2e-14
Identities = 81/289 (28%), Positives = 108/289 (37%), Gaps = 65/289 (22%)
Query: 99 RCCPGRW--GPDCI-----ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCA 151
+CCPG + G CI EC G C TC C+ G+GG C +
Sbjct: 87 QCCPGYYESGDFCIPLCTEECV---------HGRCVSP----DTCHCEPGWGGPDCSSGC 133
Query: 152 DDNLFGPSCSSVCNCVHG-VCNSGLDGDGTCECYSAYTGPKCDK-PIPECAALLCPENSR 209
D + +GP CS+ C C +G +CN G C C + + G +C++ P C +
Sbjct: 134 DSDHWGPHCSNRCQCQNGALCN---PITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQ 190
Query: 210 CSPSTE-DENKLECKCLPNYRGDGKYCDPINP-------C-LRKICHPHAHCTYLGPNRH 260
C D EC C P Y G YC+ + P C LR C C ++
Sbjct: 191 CRHGASCDPRAGECLCAPGY--TGVYCEELCPPGSHGAHCELRCPCQNGGTCHHI---TG 245
Query: 261 SCTCQEGYRGDGQVCLPVDPCQI-NFGNCPTKSTVCKYDG-----PGQSHC-------EC 307
C C G+ G VC PC FG ++ C + G GQ HC C
Sbjct: 246 ECACPPGW--TGAVC--AQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRC 301
Query: 308 KEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
+E G CS CH C +P C C+ GY G
Sbjct: 302 QEECPFGSFGFQCS------QHCDCHNGGQC---SPTTGACECEPGYKG 341
Score = 72.8 bits (177), Expect = 4e-12
Identities = 47/138 (34%), Positives = 61/138 (44%), Gaps = 17/138 (12%)
Query: 1941 CSLVIQIPRCCKGYFGRDC-QACPGGPDAP-------CNNRGVCLDQYSATGECKCNTGF 1992
CS + +C G+ G+DC QACP G P C+N C + G C C G+
Sbjct: 675 CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAE---DGACHCTPGW 731
Query: 1993 NGTAC-EMCWPGRFGPDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAV 2050
G C + C FG DC C C + CD SG+C C TG+TG C+ Q P
Sbjct: 732 TGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI---SGKCTCRTGFTGQHCE-QRCAPGT 787
Query: 2051 CTPPCSAHATCKENNTCE 2068
C C N+TC+
Sbjct: 788 FGYGCQQLCECMNNSTCD 805
Score = 66.6 bits (161), Expect = 3e-10
Identities = 41/107 (38%), Positives = 51/107 (47%), Gaps = 13/107 (12%)
Query: 1949 RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM-CWPGRFGP 2007
RC +FG+DC G C N C D S G+C C TGF G CE C PG FG
Sbjct: 739 RCPAAFFGKDC-----GRVCQCQNGASC-DHIS--GKCTCRTGFTGQHCEQRCAPGTFGY 790
Query: 2008 DCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP 2053
C C C ++ CD +TG+ C C G+ G CD A++ P
Sbjct: 791 GCQQLCECMNNSTCDH-VTGT--CYCSPGFKGIRCDQAALMMEELNP 834
Score = 63.5 bits (153), Expect = 2e-09
Identities = 38/111 (34%), Positives = 50/111 (45%), Gaps = 15/111 (13%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVC-FGNGICLDGVNGTGVCECGEGFSGT 1381
C P T+ C A FFG C VC NG D ++G C C GF+G
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCG-------RVCQCQNGASCDHISGK--CTCRTGFTGQ 777
Query: 1382 ACET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHCDNA 1430
CE C G +G C Q C C++ C+ G+C C G++G+ CD A
Sbjct: 778 HCEQRCAPGTFGYGCQQLCECMNNSTCDHVT---GTCYCSPGFKGIRCDQA 825
Score = 49.7 bits (117), Expect = 4e-05
Identities = 36/117 (30%), Positives = 48/117 (41%), Gaps = 20/117 (17%)
Query: 719 CNATVKIPKCCKGFYGPDCNQ-CPGGFSNPCSG------NGQCADSLGGNGTCICEEGFQ 771
C+A C G+ G C Q CP F G NG D + G C C GF
Sbjct: 718 CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK--CTCRTGFT 775
Query: 772 GSQCQFCSDPNKYGPRCNKKCLCV-HGTCNNRIDSDGACLTGT--CRDGSAGRLCDK 825
G C+ P +G C + C C+ + TC++ +TGT C G G CD+
Sbjct: 776 GQHCEQRCAPGTFGYGCQQLCECMNNSTCDH--------VTGTCYCSPGFKGIRCDQ 824
Score = 33.5 bits (75), Expect = 2.8
Identities = 19/65 (29%), Positives = 25/65 (38%), Gaps = 8/65 (12%)
Query: 87 CRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTA 146
CR + + RC PG +G C + C +C GTC C GF G
Sbjct: 770 CRTGFTGQHCEQRCAPGTFGYGCQQL-----CECMNNSTCDHV---TGTCYCSPGFKGIR 821
Query: 147 CETCA 151
C+ A
Sbjct: 822 CDQAA 826
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 108 bits (271), Expect = 5e-23
Identities = 86/293 (29%), Positives = 115/293 (39%), Gaps = 49/293 (16%)
Query: 99 RCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
RC G GPDC SPC C+ G +G CSC G+ G +C + D+ G
Sbjct: 107 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGE 166
Query: 159 SCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
C HG G C+C + YTGP C+ P CA C C S +
Sbjct: 167 PCR------HGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQS--GDL 218
Query: 219 KLECKCLPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCL- 276
+C CLP + +G+ C+ ++ C C C G N ++C C + GQ C
Sbjct: 219 TYDCACLPGF--EGQNCEVNVDDCPGHRCLNGGTCVD-GVNTYNCQCPPEW--TGQFCTE 273
Query: 277 PVDPCQI------NFGNC----PTKSTVCKYDGPGQSHCE---------------CKEHY 311
VD CQ+ N G C S VC G+S + C +
Sbjct: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV 333
Query: 312 QNFV-------PGVGCSMTDICKSDNPCHRNANC-TTVAPGRTECICQKGYVG 356
+F G+ C + D C S NPCH +A C T GR C C G+ G
Sbjct: 334 ASFYCACPMGKTGLLCHLDDACVS-NPCHEDAICDTNPVNGRAICTCPPGFTG 385
Score = 102 bits (255), Expect = 4e-21
Identities = 85/305 (27%), Positives = 111/305 (36%), Gaps = 69/305 (22%)
Query: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
+C +GF GPDC+ S+PC+ +C+ G C C G+QG C+ D + G
Sbjct: 107 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGE 166
Query: 787 RCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS 846
C GTC N S C G G LC+ C P C TC S
Sbjct: 167 PCRH-----GGTCLNTPGS----FRCQCPAGYTGPLCENPAVPCAP--SPCRNGGTCRQS 215
Query: 847 NG-TASCICKAGYEGD------------------------------------GTLCSE-M 868
T C C G+EG G C+E +
Sbjct: 216 GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
Query: 869 DPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSE-INNCLLP---SAGGCHD 924
D C L P C C T G H+CVC GWT G CS+ I++C CHD
Sbjct: 276 DECQ-LQPNACHNGGTCFNT-LGGHSCVCVNGWT--GESCSQNIDDCATAVCFHGATCHD 331
Query: 925 NASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTS-SGVWSCVCQ 983
+ Y C C G G+ C +C+ + CH A C + +G C C
Sbjct: 332 RVASFY-------CACPMG--KTGLLCHLDDACV--SNPCHEDAICDTNPVNGRAICTCP 380
Query: 984 EGYEG 988
G+ G
Sbjct: 381 PGFTG 385
Score = 100 bits (249), Expect = 2e-20
Identities = 97/327 (29%), Positives = 120/327 (36%), Gaps = 44/327 (13%)
Query: 42 ECRSCALNLGVKC---PDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQP 98
EC S G KC PDGY + C + S C H D +
Sbjct: 510 ECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVD----DCSPDPCHHGRCVDGIAS 565
Query: 99 ---RCCPGRWGPDCI----ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCA 151
C PG G C EC PC G C + ++ C C G G CE
Sbjct: 566 FSCACAPGYTGTRCESQVDEC---RSQPCRHGGKCLDLVD-KYLCRCPSGTTGVNCEVNI 621
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS 211
DD P C GVC G++ C C +TGP C+ I ECA+ C E C
Sbjct: 622 DDCASNP-------CTFGVCRDGINRYD-CVCQPGFTGPLCNVEINECASSPCGEGGSC- 672
Query: 212 PSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD 271
+ EN C C P P +PC + C H C Y P C C+ G+ G
Sbjct: 673 --VDGENGFRCLCPPGSL-PPLCLPPSHPCAHEPC-SHGIC-YDAPGGFRCVCEPGWSGP 727
Query: 272 G-QVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDN 330
L D C+ C T C DG G HC C Q G C + C + N
Sbjct: 728 RCSQSLARDACESQ--PCRAGGT-CSSDGMG-FHCTCPPGVQ----GRQCELLSPC-TPN 778
Query: 331 PCHRNANCTTVAPGRTE-CICQKGYVG 356
PC C + APG+ C C +G+ G
Sbjct: 779 PCEHGGRCES-APGQLPVCSCPQGWQG 804
Score = 97.4 bits (241), Expect = 2e-19
Identities = 75/264 (28%), Positives = 99/264 (37%), Gaps = 36/264 (13%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS 159
C PG G C +PC G C CSC +G+ G C+ D+
Sbjct: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE------ 813
Query: 160 CSSVCNC-VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
C+ C HG+C + L G +C C+ YTGP CD+ I +C C C +
Sbjct: 814 CAGPAPCGPHGICTN-LAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ---DGVG 869
Query: 219 KLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG-----DGQ 273
C CLP + G + ++ CL C P ++ +CTC GY G D
Sbjct: 870 SFSCSCLPGFAGP-RCARDVDECLSNPCGPGTCTDHVA--SFTCTCPPGYGGFHCEQDLP 926
Query: 274 VCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCS-MTDICKSDNPC 332
C P C N G C DG C C+ Y G C D C S PC
Sbjct: 927 DCSP-SSC-FNGGTC--------VDGVNSFSCLCRPGY----TGAHCQHEADPCLS-RPC 971
Query: 333 HRNANCTTVAPGRTECICQKGYVG 356
C+ PG C C + + G
Sbjct: 972 LHGGVCSAAHPG-FRCTCLESFTG 994
Score = 97.1 bits (240), Expect = 2e-19
Identities = 86/306 (28%), Positives = 118/306 (38%), Gaps = 37/306 (12%)
Query: 689 PANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPC 748
P + P L C GR L S A C G+ G C S PC
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACL--------CPPGWVGERCQLEDPCHSGPC 87
Query: 749 SGNGQCADSL---GGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGT-CNNRID 804
+G G C S+ +C C GF+G C DP P C HG C+ +
Sbjct: 88 AGRGVCQSSVVAGTARFSCRCPRGFRGPDCSL-PDPCLSSP-------CAHGARCS--VG 137
Query: 805 SDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTL 864
DG L +C G GR C C + C TC + G+ C C AGY G L
Sbjct: 138 PDGRFLC-SCPPGYQGRSCRSDVDEC-RVGEPCRHGGTCLNTPGSFRCQCPAGY--TGPL 193
Query: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCH 923
C +P P C C ++G T+ C C G+ G++C +++C C
Sbjct: 194 CE--NPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGF--EGQNCEVNVDDC---PGHRCL 246
Query: 924 DNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQ 983
+ +C+ G C+C + G E + C Q CH +C +T G SCVC
Sbjct: 247 NGGTCV-DGVNTYNCQCPPEWTGQ-FCTEDVDECQLQPNACHNGGTCFNTLGG-HSCVCV 303
Query: 984 EGYEGD 989
G+ G+
Sbjct: 304 NGWTGE 309
Score = 96.3 bits (238), Expect = 3e-19
Identities = 87/294 (29%), Positives = 111/294 (37%), Gaps = 52/294 (17%)
Query: 1335 ECCAGFFGPQCQ-PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE--------- 1384
+C AG+ GP C+ P A + C G C + T C C GF G CE
Sbjct: 184 QCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGH 243
Query: 1385 ------TCTEGKYGIHCD--------------QACSCVHGRCNQG-----PLGDGSCDCD 1419
TC +G +C C C+ G LG SC C
Sbjct: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV 303
Query: 1420 VGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISN 1479
GW G C + +D C A C D AS CA G +C +AC +SN
Sbjct: 304 NGWTGESC-SQNIDDCATAVCFHGATC---HDRVASFYCACPMGKTGLLCHLDDAC-VSN 358
Query: 1480 GGCSAKADCKRTTP--GRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQ 1537
C A C T P GR +CTC G+TG G +++ C C+ C T
Sbjct: 359 -PCHEDAICD-TNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNT-QGS 414
Query: 1538 AACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC-NHTGQVERTCTCKPNYIG 1590
C C YTG + T +N CL +G C A C + GQ TC C + G
Sbjct: 415 FLCQCGRGYTGP-RCETDVNECL--SGPCRNQATCLDRIGQF--TCICMAGFTG 463
Score = 94.7 bits (234), Expect = 1e-18
Identities = 91/322 (28%), Positives = 116/322 (36%), Gaps = 43/322 (13%)
Query: 675 GTCVSCSLVYWSRCPANSEPTALFTH--RCVYSG-RFGSLKSGCARYCNATVKIPKCCKG 731
G C+ Y RCP+ + + C + FG + G RY C G
Sbjct: 595 GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCV------CQPG 648
Query: 732 FYGPDCN----QCPGGFSNPCSGNGQCADSLGGNG-TCICEEGFQGSQCQFCSDPNKYGP 786
F GP CN +C S+PC G C D G NG C+C G C S P + P
Sbjct: 649 FTGPLCNVEINECA---SSPCGEGGSCVD--GENGFRCLCPPGSLPPLCLPPSHPCAHEP 703
Query: 787 RCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS 846
C HG C D+ G C G +G C + + Q C TC
Sbjct: 704 -------CSHGIC---YDAPGG-FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD 752
Query: 847 NGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGR 906
C C G + G C + PC TP C C C C QGW G R
Sbjct: 753 GMGFHCTCPPGVQ--GRQCELLSPC---TPNPCEHGGRCESAPGQLPVCSCPQGWQG-PR 806
Query: 907 DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHP 966
+++ C P+ G H + L G C C G+ G D + I C C
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNL---AGSFSCTCHGGYTGPSCD-QDINDC--DPNPCLN 860
Query: 967 LASCQSTSSGVWSCVCQEGYEG 988
SCQ G +SC C G+ G
Sbjct: 861 GGSCQD-GVGSFSCSCLPGFAG 881
Score = 92.4 bits (228), Expect = 5e-18
Identities = 102/340 (30%), Positives = 136/340 (40%), Gaps = 61/340 (17%)
Query: 1872 GVAY----GIDCLLIDPTLGGRCDTFTTFDA--SGEC---GSCVNTPSCPRWSKPKGVK- 1921
G+ Y G C+ G RC DA S C G+C + + P GV+
Sbjct: 707 GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQG 766
Query: 1922 QKCLYNLPFKRNLEGCRERC-SLVIQIPRCC--KGYFGRDCQA----CPGGPDAPCNNRG 1974
++C P N RC S Q+P C +G+ G CQ C G APC G
Sbjct: 767 RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG--PAPCGPHG 824
Query: 1975 VCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCET 2034
+C + + + C C+ G+ G +C+ DC P C + G C DG+ GS C C
Sbjct: 825 ICTN-LAGSFSCTCHGGYTGPSCDQDIN-----DCDPNPCLNGGSCQDGV-GSFSCSCLP 877
Query: 2035 GWTGPSC--DTQAVLPAVCTP-PCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNG 2091
G+ GP C D L C P C+ H + TC C Y G C+QD
Sbjct: 878 GFAGPRCARDVDECLSNPCGPGTCTDHVA---SFTCTCPPGYGG--------FHCEQDLP 926
Query: 2092 GCAKVARCSQKGTKV------SCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTG 2145
C+ + C GT V SC C+ GY G H E DPC L+ C C
Sbjct: 927 DCSP-SSCFNGGTCVDGVNSFSCLCRPGYTG-AHCQHEADPC---LSRPCLHGGVCSAAH 981
Query: 2146 PGKHKCECKSHYVGDGLNCEPEQLPIDRC----LQDNGQC 2181
PG +C C + G C Q +D C Q+ G+C
Sbjct: 982 PG-FRCTCLESFTGP--QC---QTLVDWCSRQPCQNGGRC 1015
Score = 91.3 bits (225), Expect = 1e-17
Identities = 86/297 (28%), Positives = 114/297 (38%), Gaps = 66/297 (22%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
+C +G+ GP C N+C S PC C D +G TCIC GF G+ C+ D
Sbjct: 418 QCGRGYTGPRCETDVNEC---LSGPCRNQATCLDRIG-QFTCICMAGFTGTYCEVDIDEC 473
Query: 783 KYGPRCNK----------KCLCVHG----TCNNRIDSDGA--CLTGT------------C 814
+ P N C C G TC +D + C G C
Sbjct: 474 QSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRC 533
Query: 815 RDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLC-SEMDPCTG 873
+G G LCD+ C P CH H C + SC C GY GT C S++D C
Sbjct: 534 AEGFEGTLCDRNVDDCSP--DPCH-HGRCVDGIASFSCACAPGY--TGTRCESQVDECRS 588
Query: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTG-----NGRDCSEINNCLLPSAGGCHDNASC 928
C +C+ + C C G TG N DC+ N C + G C D
Sbjct: 589 QP---CRHGGKCLDL-VDKYLCRCPSGTTGVNCEVNIDDCAS-NPC---TFGVCRD---- 636
Query: 929 LYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
G + +C C+ GF G + E I C + C SC +G + C+C G
Sbjct: 637 ---GINRYDCVCQPGFTGPLCNVE-INEC--ASSPCGEGGSCVDGENG-FRCLCPPG 686
Score = 91.3 bits (225), Expect = 1e-17
Identities = 102/402 (25%), Positives = 140/402 (34%), Gaps = 118/402 (29%)
Query: 675 GTCVSCSLVYWSRCPANSEP------TALFTHRCVYSGRFGSLKSGCARYCNATVKIPKC 728
GTC S + + CP + + + C + GR S + + C
Sbjct: 747 GTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPG--------QLPVCSC 798
Query: 729 CKGFYGPDCNQ----CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ-------- 776
+G+ GP C Q C G PC +G C + L G+ +C C G+ G C
Sbjct: 799 PQGWQGPRCQQDVDECAG--PAPCGPHGICTN-LAGSFSCTCHGGYTGPSCDQDINDCDP 855
Query: 777 -------FCSD----------PNKYGPRCNK---KCL---CVHGTCNNRIDSDGACLTGT 813
C D P GPRC + +CL C GTC + + A T T
Sbjct: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHV----ASFTCT 911
Query: 814 CRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEG------------- 860
C G G C++ C P C TC + SC+C+ GY G
Sbjct: 912 CPPGYGGFHCEQDLPDCSP--SSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
Query: 861 ---DGTLCSEMDP---CTGL---------------TPGGCSRNAECIKTGTGTHTCVCQQ 899
G +CS P CT L + C C++TG C+C
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA---YCLCPP 1026
Query: 900 GWTGNGRD-----CSEIN-------NCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGN 947
GW+G D C E L + G C D S Y C C +G G+
Sbjct: 1027 GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY-------CVCPEGRTGS 1079
Query: 948 GIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
+ E + CL Q C +C+ G + C C GY GD
Sbjct: 1080 HCEQE-VDPCLAQP--CQHGGTCRGYMGG-YMCECLPGYNGD 1117
Score = 90.5 bits (223), Expect = 2e-17
Identities = 74/262 (28%), Positives = 103/262 (39%), Gaps = 31/262 (11%)
Query: 101 CP-GRWGPDCIECPGGAGSPCNGRGSC-AEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
CP G+ G C +PC+ C + G C+C GF G AC+ D+ G
Sbjct: 340 CPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGA 399
Query: 159 S-CSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDE 217
+ C + CV+ G C+C YTGP+C+ + EC + C + C +
Sbjct: 400 NPCEHLGRCVN------TQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC---LDRI 450
Query: 218 NKLECKCLPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVC- 275
+ C C+ + G YC+ I+ C C C N SCTC G+ G C
Sbjct: 451 GQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGVCKD-RVNGFSCTCPSGF--SGSTCQ 505
Query: 276 LPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSM-TDICKSDNPCHR 334
L VD C + P ++ D P C C E ++ G C D C D PCH
Sbjct: 506 LDVDEC----ASTPCRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPD-PCHH 556
Query: 335 NANCTTVAPGRTECICQKGYVG 356
+A C C GY G
Sbjct: 557 GRCVDGIA--SFSCACAPGYTG 576
Score = 90.1 bits (222), Expect = 2e-17
Identities = 96/346 (27%), Positives = 122/346 (35%), Gaps = 104/346 (30%)
Query: 1336 CCAGFFGPQCQPCPGN-AQNVCFGNGICLDGVNGTGVCECGEGFSGTACE---------- 1384
C +G G C+ + A N C G+C DG+N C C GF+G C
Sbjct: 608 CPSGTTGVNCEVNIDDCASNPCTF-GVCRDGINRYD-CVCQPGFTGPLCNVEINECASSP 665
Query: 1385 -----TCTEGKYGIHC--------------DQACS---CVHGRCNQGPLGDGSCDCDVGW 1422
+C +G+ G C C+ C HG C P G C C+ GW
Sbjct: 666 CGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAP-GGFRCVCEPGW 724
Query: 1423 RGVHCDNATTEDNCNG-TCHTSANCLTNSDGTA-SCKCAAGFQGNG----TICTAINACE 1476
G C + D C C C +SDG C C G QG + CT N CE
Sbjct: 725 SGPRCSQSLARDACESQPCRAGGTC--SSDGMGFHCTCPPGVQGRQCELLSPCTP-NPCE 781
Query: 1477 ISNGG-----------------------------CSAKADCK-----RTTPGRRVCTCKA 1502
+GG C+ A C G CTC
Sbjct: 782 --HGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG 839
Query: 1503 GYTG----DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINV 1558
GYTG I + NPCL N G C Q G +C+CLP + G + ++
Sbjct: 840 GYTGPSCDQDINDCDPNPCL-NGGSC-------QDGVGSFSCSCLPGFAGP-RCARDVDE 890
Query: 1559 CLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELP 1604
CL + C +H TCTC P Y GF C Q+LP
Sbjct: 891 CL--SNPCGPGTCTDHVASF--TCTCPPGY--GGFHCE----QDLP 926
Score = 88.6 bits (218), Expect = 7e-17
Identities = 78/306 (25%), Positives = 103/306 (33%), Gaps = 68/306 (22%)
Query: 102 PGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACE--------TCADD 153
PG P C++ GSPC G C + C C G+ G C+ CA
Sbjct: 36 PGAAAPPCLD-----GSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGR 90
Query: 154 NLF--------------------GPSCS--SVC---NCVHGV-CNSGLDGDGTCECYSAY 187
+ GP CS C C HG C+ G DG C C Y
Sbjct: 91 GVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY 150
Query: 188 TGPKCDKPIPEC-AALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINPCLRKI 245
G C + EC C C C+C Y G C+ P PC
Sbjct: 151 QGRSCRSDVDECRVGEPCRHGGTC---LNTPGSFRCQCPAGY--TGPLCENPAVPCAPSP 205
Query: 246 CHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCP----TKSTVCKYDGPG 301
C C G + C C G+ G C++N +CP C DG
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQN--------CEVNVDDCPGHRCLNGGTC-VDGVN 256
Query: 302 QSHCECKEHYQNFVPGVGCSM-TDICK-SDNPCHRNANCTTVAPGRTECICQKGYVGDGL 359
+C+C + G C+ D C+ N CH C G + C+C G+ G+
Sbjct: 257 TYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS-CVCVNGWTGE-- 309
Query: 360 TCYGNI 365
+C NI
Sbjct: 310 SCSQNI 315
Score = 88.6 bits (218), Expect = 7e-17
Identities = 102/375 (27%), Positives = 138/375 (36%), Gaps = 85/375 (22%)
Query: 1876 GIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTP------SCPRWSKPKGVKQKCLYNLP 1929
G DC L DP L C A G C P SCP P + C ++
Sbjct: 114 GPDCSLPDPCLSSPC-------AHG--ARCSVGPDGRFLCSCP----PGYQGRSCRSDVD 160
Query: 1930 FKRNLEGCRERCSLVIQIP-----RCCKGYFGRDCQ--ACPGGPDAPCNNRGVCLDQYSA 1982
R E CR + P +C GY G C+ A P P +PC N G C
Sbjct: 161 ECRVGEPCRHG-GTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDL 218
Query: 1983 TGECKCNTGFNGTACEM----C-------------------------WPGRFGPDCL--- 2010
T +C C GF G CE+ C W G+F + +
Sbjct: 219 TYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDEC 278
Query: 2011 ---PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT- 2066
P C + G C + + G C+C GWTG SC + T C ATC +
Sbjct: 279 QLQPNACHNGGTCFNTL-GGHSCVCVNGWTGESCSQN--IDDCATAVCFHGATCHDRVAS 335
Query: 2067 --CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK--GTKVSCSCQKGYKGDGHSCT 2122
C C + G+ C + D C + C + A C + C+C G+ G G
Sbjct: 336 FYCACPMG--KTGLLCHLDDACV--SNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQ 390
Query: 2123 EIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCH 2182
++D C+ G N C C T G C+C Y G CE + ++ CL +G C
Sbjct: 391 DVDECSIGAN-PCEHLGRCVNT-QGSFLCQCGRGYTGP--RCETD---VNECL--SGPCR 441
Query: 2183 ADAKCVDLHFQDTTV 2197
A C+D Q T +
Sbjct: 442 NQATCLDRIGQFTCI 456
Score = 86.3 bits (212), Expect = 4e-16
Identities = 96/380 (25%), Positives = 131/380 (34%), Gaps = 70/380 (18%)
Query: 649 TGVLIPPSIVPILPHRCDETKREMKLGTC-VSCSLVYWSRCPANSEPTALFT-------H 700
TG L VP P C GTC S L Y C E H
Sbjct: 190 TGPLCENPAVPCAPSPCRNG------GTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGH 243
Query: 701 RCVYSGRFGSLKSGCARY-CNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLG 759
RC+ G + G Y C P+ F D ++C N C G C ++LG
Sbjct: 244 RCLNGG---TCVDGVNTYNCQCP---PEWTGQFCTEDVDECQLQ-PNACHNGGTCFNTLG 296
Query: 760 GNGTCICEEGFQGSQCQ------------------------FCSDP-NKYGPRCNKKCLC 794
G+ +C+C G+ G C +C+ P K G C+ C
Sbjct: 297 GH-SCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDAC 355
Query: 795 VHGTCNNRIDSDGACLTG----TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 850
V C+ D + G TC G G CD+ C C C + G+
Sbjct: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSF 415
Query: 851 SCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGN--GRDC 908
C C GY G ++++ C G C A C+ G TC+C G+TG D
Sbjct: 416 LCQCGRGYTGP-RCETDVNECLS---GPCRNQATCLDR-IGQFTCICMAGFTGTYCEVDI 470
Query: 909 SEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLA 968
E + + G C D + C C GF G+ + + C + C A
Sbjct: 471 DECQSSPCVNGGVCKDRVNGF-------SCTCPSGFSGSTCQLD-VDEC--ASTPCRNGA 520
Query: 969 SCQSTSSGVWSCVCQEGYEG 988
C G + C C EG+EG
Sbjct: 521 KCVDQPDG-YECRCAEGFEG 539
Score = 86.3 bits (212), Expect = 4e-16
Identities = 81/312 (25%), Positives = 116/312 (37%), Gaps = 49/312 (15%)
Query: 685 WS--RCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPG 742
WS RC + A + C G S G +C C G G C
Sbjct: 724 WSGPRCSQSLARDACESQPCRAGGTCSS--DGMGFHCT-------CPPGVQGRQCELLSP 774
Query: 743 GFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ----FCSDPNKYGPRCNKKCLCVHGT 798
NPC G+C + G C C +G+QG +CQ C+ P GP HG
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGP---------HGI 825
Query: 799 CNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY 858
C N S + TC G G CD+ + C P C +C+ G+ SC C G+
Sbjct: 826 CTNLAGS----FSCTCHGGYTGPSCDQDINDCDP--NPCLNGGSCQDGVGSFSCSCLPGF 879
Query: 859 EGDGTLCSEMDPCTG--LTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLL 916
G ++D C PG C+ + + TC C G+ G + ++ +C
Sbjct: 880 AGP-RCARDVDECLSNPCGPGTCTDH-------VASFTCTCPPGYGGFHCE-QDLPDC-- 928
Query: 917 PSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSG 976
S C + +C+ G C C+ G+ G E CL + C C + G
Sbjct: 929 -SPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHE-ADPCLSR--PCLHGGVCSAAHPG 983
Query: 977 VWSCVCQEGYEG 988
+ C C E + G
Sbjct: 984 -FRCTCLESFTG 994
Score = 85.9 bits (211), Expect = 5e-16
Identities = 82/270 (30%), Positives = 107/270 (39%), Gaps = 48/270 (17%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGIC-LDGVNGTGVCECGEGFSGTAC----ETCTEGK 1390
C G G C N C + IC + VNG +C C GF+G AC + C+ G
Sbjct: 340 CPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIG- 398
Query: 1391 YGIHCDQACSCVH-GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN 1449
A C H GRC G C C G+ G C+ E +G C A CL +
Sbjct: 399 -------ANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCETDVNE-CLSGPCRNQATCL-D 448
Query: 1450 SDGTASCKCAAGFQGNGTICTA-INACEIS---NGGCSAKADCKRTTPGRRVCTCKAGYT 1505
G +C C AGF GT C I+ C+ S NGG CK G CTC +G++
Sbjct: 449 RIGQFTCICMAGF--TGTYCEVDIDECQSSPCVNGGV-----CKDRVNGFS-CTCPSGFS 500
Query: 1506 GDGIVC-LEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNG 1564
G C L+++ C C A+C P+ C C + G +C
Sbjct: 501 GS--TCQLDVDECAST--PCRNGAKCVDQ-PDGYECRCAEGFEG--------TLCDRNVD 547
Query: 1565 GCSEFAICNH----TGQVERTCTCKPNYIG 1590
CS C+H G +C C P Y G
Sbjct: 548 DCSPDP-CHHGRCVDGIASFSCACAPGYTG 576
Score = 85.9 bits (211), Expect = 5e-16
Identities = 80/292 (27%), Positives = 104/292 (35%), Gaps = 77/292 (26%)
Query: 1950 CCKGYFG----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C G+ G RD C P P G C D + A+ C C G+ G CE P
Sbjct: 875 CLPGFAGPRCARDVDECLSNPCGP----GTCTD-HVASFTCTCPPGYGGFHCEQDLP--- 926
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENN 2065
DC P C + G C DG+ S CLC G+TG C +A + PC C +
Sbjct: 927 --DCSPSSCFNGGTCVDGV-NSFSCLCRPGYTGAHCQHEA--DPCLSRPCLHGGVCSAAH 981
Query: 2066 ---TCECNLDYEGDGITCTVVDFCKQ---DNGG--------------------------- 2092
C C + G T+VD+C + NGG
Sbjct: 982 PGFRCTCLESFTGPQCQ-TLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPC 1040
Query: 2093 --------------CAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEH 2138
C +C + + C C +G G H E+DPC L C
Sbjct: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG-SHCEQEVDPC---LAQPCQHG 1096
Query: 2139 ATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
TC+ G + CEC Y GD NCE + +D C C C+DL
Sbjct: 1097 GTCR-GYMGGYMCECLPGYNGD--NCEDD---VDECASQ--PCQHGGSCIDL 1140
Score = 85.5 bits (210), Expect = 6e-16
Identities = 76/255 (29%), Positives = 97/255 (38%), Gaps = 47/255 (18%)
Query: 1950 CCKGYFGRDCQACPG--GP----------DAPCNNRGVCLDQYSATGECKCNTGFNGTAC 1997
C G DC PG GP +PC G C+D G NG C
Sbjct: 634 CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVD------------GENGFRC 681
Query: 1998 EMCWPGRFGPDCLP----CG---CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAV 2050
+C PG P CLP C CS HG C D G +C+CE GW+GP C A
Sbjct: 682 -LCPPGSLPPLCLPPSHPCAHEPCS-HGICYDA-PGGFRCVCEPGWSGPRCSQSLARDAC 738
Query: 2051 CTPPCSAHATCKENNT---CECNLDYEGDGITCTVVDFCKQDNGGCAKVARC-SQKGTKV 2106
+ PC A TC + C C +G C ++ C + C RC S G
Sbjct: 739 ESQPCRAGGTCSSDGMGFHCTCPPGVQGR--QCELLSPCTPN--PCEHGGRCESAPGQLP 794
Query: 2107 SCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
CSC +G++G ++D CA C H C G C C Y G + +
Sbjct: 795 VCSCPQGWQGP-RCQQDVDECAG--PAPCGPHGICTNLA-GSFSCTCHGGYTGPSCDQDI 850
Query: 2167 EQLPIDRCLQDNGQC 2181
+ CL + G C
Sbjct: 851 NDCDPNPCL-NGGSC 864
Score = 82.0 bits (201), Expect = 7e-15
Identities = 78/271 (28%), Positives = 106/271 (39%), Gaps = 42/271 (15%)
Query: 100 CCPGRWGPDCIE-CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
C PG G C + P + S C G+C +G+ + +C C+ G+ G C+ AD L P
Sbjct: 912 CPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVN-SFSCLCRPGYTGAHCQHEADPCLSRP 970
Query: 159 SCSSVCNCVHG-VCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDE 217
C+HG VC++ G C C ++TGP+C + C+ C RC +
Sbjct: 971 -------CLHGGVCSAAHPGF-RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCV-----Q 1017
Query: 218 NKLECKCLPNYRGDGKYCDPIN-PC----------LRKICHPHAHCTYLGPNRHSCTCQE 266
C C P + G+ CD + PC L ++C C + H C C E
Sbjct: 1018 TGAYCLCPPGW--SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD-EDSSHYCVCPE 1074
Query: 267 GYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC-SMTDI 325
G G VDPC C T Y G CEC Y G C D
Sbjct: 1075 GRTG-SHCEQEVDPCLAQ--PCQHGGTCRGY--MGGYMCECLPGYN----GDNCEDDVDE 1125
Query: 326 CKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
C S PC +C + R C C G +G
Sbjct: 1126 CAS-QPCQHGGSCIDLV-ARYLCSCPPGTLG 1154
Score = 81.6 bits (200), Expect = 9e-15
Identities = 79/271 (29%), Positives = 103/271 (38%), Gaps = 44/271 (16%)
Query: 1949 RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTAC----EMCWPGR 2004
RC +G+ G DC +PC + C C C G+ G +C + C R
Sbjct: 107 RCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDEC---R 163
Query: 2005 FGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKE 2063
G C HG GS +C C G+TGP C+ AV C P PC TC++
Sbjct: 164 VGEPC------RHGGTCLNTPGSFRCQCPAGYTGPLCENPAV---PCAPSPCRNGGTCRQ 214
Query: 2064 NN----TCECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDG 2118
+ C C +EG C V VD C C C +C C + G
Sbjct: 215 SGDLTYDCACLPGFEGQ--NCEVNVDDCPGHR--CLNGGTCVDGVNTYNCQCPPEW--TG 268
Query: 2119 HSCTE-IDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQD 2177
CTE +D C N CH TC T G H C C + + G+ +C ID C
Sbjct: 269 QFCTEDVDECQLQPN-ACHNGGTCFNT-LGGHSCVCVNGWTGE--SCSQN---IDDCA-- 319
Query: 2178 NGQCHADAKCVDLHFQDTTVGVFHLRSPLGQ 2208
C A C D V F+ P+G+
Sbjct: 320 TAVCFHGATCHD------RVASFYCACPMGK 344
Score = 80.1 bits (196), Expect = 3e-14
Identities = 82/306 (26%), Positives = 108/306 (35%), Gaps = 60/306 (19%)
Query: 728 CCKGFYGPDC-NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ----FCS-DP 781
C G+ G C ++ S PC G C+ + G C C E F G QCQ +CS P
Sbjct: 950 CRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF-RCTCLESFTGPQCQTLVDWCSRQP 1008
Query: 782 NKYGPRC---NKKCLCVHGTCNNRID----------------------SDGACLTG---- 812
+ G RC CLC G D + G C+
Sbjct: 1009 CQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
Query: 813 --TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDP 870
C +G G C+++ C Q C TC G C C GY GD ++D
Sbjct: 1069 YCVCPEGRTGSHCEQEVDPC--LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE-DDVDE 1125
Query: 871 CTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG-----NGRDCSEINNCLLPSAGGCHDN 925
C C CI + C C G G N DC L S C N
Sbjct: 1126 CASQP---CQHGGSCIDL-VARYLCSCPPGTLGVLCEINEDDCGP--GPPLDSGPRCLHN 1179
Query: 926 ASCLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHP--LASCQSTSSGVWSCVC 982
+C+ + G C C G+ G+ CE I C ++G CH C G + C+C
Sbjct: 1180 GTCVDL-VGGFRCTCPPGY--TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRCLC 1234
Query: 983 QEGYEG 988
G+ G
Sbjct: 1235 HAGFSG 1240
Score = 79.3 bits (194), Expect = 4e-14
Identities = 65/240 (27%), Positives = 85/240 (35%), Gaps = 37/240 (15%)
Query: 1956 GRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCS 2015
G A P +PC N G C S C C G+ G C++ P GP C+
Sbjct: 35 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP------CA 88
Query: 2016 DHGQCDDGI---TGSGQCLCETGWTGPSCDTQAVLPAVC-TPPCSAHATCKENN----TC 2067
G C + T C C G+ GP C LP C + PC+ A C C
Sbjct: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCS----LPDPCLSSPCAHGARCSVGPDGRFLC 144
Query: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVS------CSCQKGYKGDGHSC 2121
C Y+G C+ D C C GT ++ C C GY G
Sbjct: 145 SCPPGYQGRS--------CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 2122 TEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
+ PCA C TC+ +G + C C + G + P RCL + G C
Sbjct: 197 PAV-PCAP---SPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCL-NGGTC 251
Score = 79.0 bits (193), Expect = 6e-14
Identities = 70/293 (23%), Positives = 95/293 (32%), Gaps = 53/293 (18%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
C GF GP C + C C G +G +C C G+ G +C + + C
Sbjct: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD-----EC 162
Query: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455
C HG G C C G+ G C+N C C + D T
Sbjct: 163 RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYD 221
Query: 1456 CKCAAGFQG------------------------------------NGTICTA-INACEIS 1478
C C GF+G G CT ++ C++
Sbjct: 222 CACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ 281
Query: 1479 NGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQA 1538
C C T G C C G+TG+ I+ C C A C A
Sbjct: 282 PNACHNGGTCFNTLGGHS-CVCVNGWTGES-CSQNIDDCAT--AVCFHGATCHD---RVA 334
Query: 1539 ACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERT-CTCKPNYIG 1590
+ C G +C L + C+ + C E AIC+ R CTC P + G
Sbjct: 335 SFYCACPMGKTGLLCHLDDACV--SNPCHEDAICDTNPVNGRAICTCPPGFTG 385
Score = 79.0 bits (193), Expect = 6e-14
Identities = 75/274 (27%), Positives = 99/274 (36%), Gaps = 55/274 (20%)
Query: 1950 CCKGYFGRDCQA-CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G CQ PC N C+DQ EC+C GF GT C+ R D
Sbjct: 495 CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY-ECRCAEGFEGTLCD-----RNVDD 548
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE-NNTC 2067
C P C HG+C DGI S C C G+TG C++Q + + PC C + +
Sbjct: 549 CSPDPCH-HGRCVDGIA-SFSCACAPGYTGTRCESQ--VDECRSQPCRHGGKCLDLVDKY 604
Query: 2068 ECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGD--------- 2117
C G+ C V +D C + C + C CQ G+ G
Sbjct: 605 LCRCPSGTTGVNCEVNIDDCASNP---CTFGVCRDGINRYDCVCQPGFTGPLCNVEINEC 661
Query: 2118 -GHSCTEIDPCADGLNG--------------------GCHE---HATCKMTGPGKHKCEC 2153
C E C DG NG HE H C PG +C C
Sbjct: 662 ASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC-YDAPGGFRCVC 720
Query: 2154 KSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
+ + G + + L D C ++ C A C
Sbjct: 721 EPGWSGPRCS---QSLARDAC--ESQPCRAGGTC 749
Score = 77.0 bits (188), Expect = 2e-13
Identities = 70/251 (27%), Positives = 98/251 (39%), Gaps = 40/251 (15%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE--CKCNTGFNGTACEMCWPGRFGP 2007
C G G C PC+ +C D G C C GF G AC+
Sbjct: 340 CPMGKTGLLCHLDDACVSNPCHEDAIC-DTNPVNGRAICTCPPGFTGGACDQ-------- 390
Query: 2008 DCLPCG-----CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCK 2062
D C C G+C + GS C C G+TGP C+T + + PC ATC
Sbjct: 391 DVDECSIGANPCEHLGRCVN-TQGSFLCQCGRGYTGPRCETD--VNECLSGPCRNQATCL 447
Query: 2063 E---NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGH 2119
+ TC C + G T VD + + C C + SC+C G+ G
Sbjct: 448 DRIGQFTCICMAGFTG---TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGS-- 502
Query: 2120 SC-TEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDN 2178
+C ++D CA + C A C + P ++C C + +G C+ +D C D
Sbjct: 503 TCQLDVDECA---STPCRNGAKC-VDQPDGYECRCAEGF--EGTLCDRN---VDDCSPD- 552
Query: 2179 GQCHADAKCVD 2189
CH +CVD
Sbjct: 553 -PCH-HGRCVD 561
Score = 75.5 bits (184), Expect = 6e-13
Identities = 88/328 (26%), Positives = 121/328 (36%), Gaps = 98/328 (29%)
Query: 1336 CCAGFFGPQCQP----CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET------ 1385
C GF G C C A N C G C++ G+ +C+CG G++G CET
Sbjct: 379 CPPGFTGGACDQDVDECSIGA-NPCEHLGRCVN-TQGSFLCQCGRGYTGPRCETDVNECL 436
Query: 1386 --------------------CTEGKYGIHCD------QACSCVHGRCNQGPLGDGSCDCD 1419
C G G +C+ Q+ CV+G + + SC C
Sbjct: 437 SGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCP 496
Query: 1420 VGWRGVHCDNATTEDNCNGT-CHTSANCLTNSDGTASCKCAAGFQGNGTIC--------- 1469
G+ G C D C T C A C+ DG C+CA GF+ GT+C
Sbjct: 497 SGFSGSTCQ--LDVDECASTPCRNGAKCVDQPDG-YECRCAEGFE--GTLCDRNVDDCSP 551
Query: 1470 -----------TAINACEISNG----GCSAKADCKRTTPGRR-----------VCTCKAG 1503
A +C + G C ++ D R+ P R +C C +G
Sbjct: 552 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSG 611
Query: 1504 YTGDGIVCLEINPCLENHGGCDKNAECT----QTGPNQAACNCLPAYTGDGKVCTL-INV 1558
TG +N C N C N CT + G N+ C C P +T G +C + IN
Sbjct: 612 TTG-------VN-CEVNIDDCASN-PCTFGVCRDGINRYDCVCQPGFT--GPLCNVEINE 660
Query: 1559 CLTKNGGCSEFAICNHTGQVERTCTCKP 1586
C + C E C G+ C C P
Sbjct: 661 C--ASSPCGEGGSC-VDGENGFRCLCPP 685
Score = 74.7 bits (182), Expect = 1e-12
Identities = 64/206 (31%), Positives = 83/206 (40%), Gaps = 28/206 (13%)
Query: 1395 CDQACSCVHG-RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC-NGTCHTSANCLTN-SD 1451
C C +G RC Q P + +C C GW G C ED C +G C C ++
Sbjct: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ---LEDPCHSGPCAGRGVCQSSVVA 99
Query: 1452 GTA--SCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTG--- 1506
GTA SC+C GF+G C+ + C + C+ A C GR +C+C GY G
Sbjct: 100 GTARFSCRCPRGFRGPD--CSLPDPC--LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSC 155
Query: 1507 --DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNG 1564
D C PC HGG C T P C C YT G +C V +
Sbjct: 156 RSDVDECRVGEPC--RHGG-----TCLNT-PGSFRCQCPAGYT--GPLCENPAVPCAPS- 204
Query: 1565 GCSEFAICNHTGQVERTCTCKPNYIG 1590
C C +G + C C P + G
Sbjct: 205 PCRNGGTCRQSGDLTYDCACLPGFEG 230
Score = 71.6 bits (174), Expect = 9e-12
Identities = 69/253 (27%), Positives = 90/253 (35%), Gaps = 31/253 (12%)
Query: 1349 PGNAQNVCFGNGICLDGVNGT------GVCECGEGFSGTACETCTEGKYGIHCDQACSCV 1402
PG A C C +G T C C G+ G C+ C
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDP------CHSGPCAG 89
Query: 1403 HGRCNQGPLGDG---SCDCDVGWRGVHCDNATTEDNC-NGTCHTSANCLTNSDGTASCKC 1458
G C + SC C G+RG C + D C + C A C DG C C
Sbjct: 90 RGVCQSSVVAGTARFSCRCPRGFRGPDC---SLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
Query: 1459 AAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-INPC 1517
G+QG + + ++ C + C C TPG C C AGYTG +C PC
Sbjct: 147 PPGYQGR-SCRSDVDECRVGE-PCRHGGTC-LNTPGSFRCQCPAGYTGP--LCENPAVPC 201
Query: 1518 LENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQ 1577
+ C C Q+G C CLP + +G+ C +NV C C G
Sbjct: 202 APS--PCRNGGTCRQSGDLTYDCACLPGF--EGQNCE-VNVDDCPGHRCLNGGTC-VDGV 255
Query: 1578 VERTCTCKPNYIG 1590
C C P + G
Sbjct: 256 NTYNCQCPPEWTG 268
Score = 71.6 bits (174), Expect = 9e-12
Identities = 77/294 (26%), Positives = 101/294 (34%), Gaps = 62/294 (21%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
C G G QC+ N C G C VC C +G+ G C+ + C
Sbjct: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD-----EC 814
Query: 1396 DQACSC-VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTA 1454
C HG C G SC C G+ G CD + + N C +C + G+
Sbjct: 815 AGPAPCGPHGICT-NLAGSFSCTCHGGYTGPSCDQDINDCDPN-PCLNGGSC-QDGVGSF 871
Query: 1455 SCKCAAGFQ----------------GNGT----ICTAINACEISNGGCSAKADCKRTTPG 1494
SC C GF G GT + + C GG + D +P
Sbjct: 872 SCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS 931
Query: 1495 RRV-------------CTCKAGYTG-----DGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
C C+ GYTG + CL PCL HGG C+ P
Sbjct: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLS-RPCL--HGGV-----CSAAHPG 983
Query: 1537 QAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
C CL ++TG + TL++ C C C TG C C P + G
Sbjct: 984 -FRCTCLESFTGP-QCQTLVDWC--SRQPCQNGGRCVQTGAY---CLCPPGWSG 1030
Score = 68.6 bits (166), Expect = 8e-11
Identities = 99/371 (26%), Positives = 131/371 (35%), Gaps = 75/371 (20%)
Query: 29 RRCDRKSLLTIRTECRSCALNLGVK----CPDGYTMITSGSVGVRDCRYTFEVRTYS--- 81
R CD +SL CR A +GV+ C G + S C E RT S
Sbjct: 1031 RLCDIRSL-----PCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP---EGRTGSHCE 1082
Query: 82 ------LSLPGCRH--ICRKDYL---QPRCCPGRWGPDCI----ECPGGAGSPCNGRGSC 126
L+ P C+H CR Y+ C PG G +C EC A PC GSC
Sbjct: 1083 QEVDPCLAQP-CQHGGTCR-GYMGGYMCECLPGYNGDNCEDDVDEC---ASQPCQHGGSC 1137
Query: 127 AEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSA 186
+ + CSC G G CE DD GP S C+H L G C C
Sbjct: 1138 ID-LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1196
Query: 187 YTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPI-NPCLRKI 245
YTG +C+ I EC + C + C C + G C + +PC +
Sbjct: 1197 YTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF--SGPRCQTVLSPCESQP 1254
Query: 246 CHPHAHC-TYLGPN---RHSCTCQEGY---------RGDGQVCLPVD-PCQINFGN---- 287
C C GP +C C + + R ++ PV PCQ
Sbjct: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314
Query: 288 CPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANC--TTVAPGR 345
CP PG S C+ PG ++ + PC +C +AP
Sbjct: 1315 CP----------PGLSGPSCRS-----FPGSPPGASNASCAAAPCLHGGSCRPAPLAP-F 1358
Query: 346 TECICQKGYVG 356
C C +G+ G
Sbjct: 1359 FRCACAQGWTG 1369
Score = 68.2 bits (165), Expect = 1e-10
Identities = 78/315 (24%), Positives = 111/315 (35%), Gaps = 82/315 (26%)
Query: 1336 CCAGFFGPQCQPCPG-NAQNVCFGNGICLDGVNGTGV-CECGEGFSGTACE--------- 1384
C F GPQCQ ++ C G C+ TG C C G+SG C+
Sbjct: 988 CLESFTGPQCQTLVDWCSRQPCQNGGRCVQ----TGAYCLCPPGWSGRLCDIRSLPCREA 1043
Query: 1385 ---------------------------TCTEGKYGIHCDQ------ACSCVHGRCNQGPL 1411
C EG+ G HC+Q A C HG +G +
Sbjct: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM 1103
Query: 1412 GDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTA 1471
G C+C G+ G +C++ ++ + C +C+ + C C G G +
Sbjct: 1104 GGYMCECLPGYNGDNCED-DVDECASQPCQHGGSCI-DLVARYLCSCPPGTLG---VLCE 1158
Query: 1472 INACEISNG-------GCSAKADCKRTTPGRRVCTCKAGYTGDGIVC-LEINPCLENHGG 1523
IN + G C C G R CTC GYT G+ C +IN C
Sbjct: 1159 INEDDCGPGPPLDSGPRCLHNGTCVDLVGGFR-CTCPPGYT--GLRCEADINECRSGACH 1215
Query: 1524 CDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCT 1583
+C Q C C ++G + T+++ C E C H GQ
Sbjct: 1216 AAHTRDCLQDPGGGFRCLCHAGFSGP-RCQTVLSPC--------ESQPCQHGGQ------ 1260
Query: 1584 CKPNYIGDG---FTC 1595
C+P+ G FTC
Sbjct: 1261 CRPSPGPGGGLTFTC 1275
Score = 68.2 bits (165), Expect = 1e-10
Identities = 74/282 (26%), Positives = 107/282 (37%), Gaps = 56/282 (19%)
Query: 748 CSGNGQCADSLGGNGTCICEEGFQGSQCQ-----FCSDPNKYGPRC-----NKKCLCVHG 797
C GQC D + C+C EG GS C+ + P ++G C C C+ G
Sbjct: 1055 CQAGGQCVDE-DSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPG 1113
Query: 798 ----TCNNRIDS--------DGACL------TGTCRDGSAGRLCDKQTSACGPYVQF--- 836
C + +D G+C+ +C G+ G LC+ CGP
Sbjct: 1114 YNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSG 1173
Query: 837 --CHIHATCEYSNGTASCICKAGYEGDGTLC-SEMDPCTGLTPGGC--SRNAECIKTGTG 891
C + TC G C C GY G C ++++ C G C + +C++ G
Sbjct: 1174 PRCLHNGTCVDLVGGFRCTCPPGY--TGLRCEADINECRS---GACHAAHTRDCLQDPGG 1228
Query: 892 THTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL-YVGPGQN---ECECKKGFRGN 947
C+C G++G R + ++ C + C C GPG C C + F G
Sbjct: 1229 GFRCLCHAGFSG-PRCQTVLSPC---ESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGP 1284
Query: 948 GIDCEPIT-SCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
CE + SC E +C CQ T G C C G G
Sbjct: 1285 --RCERVARSCREL--QCPVGVPCQQTPRGP-RCACPPGLSG 1321
Score = 62.8 bits (151), Expect = 4e-09
Identities = 79/325 (24%), Positives = 109/325 (33%), Gaps = 59/325 (18%)
Query: 701 RCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGG 760
RC+++G L G C +C D N+C G + + C GG
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRC-----EADINECRSGACH-AAHTRDCLQDPGG 1228
Query: 761 NGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSA- 819
C+C GF G +CQ P + P C HG G LT TC
Sbjct: 1229 GFRCLCHAGFSGPRCQTVLSPCESQP-------CQHGGQCRPSPGPGGGLTFTCHCAQPF 1281
Query: 820 -GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGG 878
G C++ +C C + C+ + C C G G P G +
Sbjct: 1282 WGPRCERVARSCRELQ--CPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSP-PGASNAS 1338
Query: 879 CSRNAECIKTGT-------GTHTCVCQQGWTG-------NGRDCSEINNCLLPSAG---- 920
C+ A C+ G+ C C QGWTG + SE C P A
Sbjct: 1339 CAA-APCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRC--PRAACQAK 1395
Query: 921 -------------GC-HDNASC-LYVGPGQNECECKKGFR-GNGIDCEPITS---CLEQT 961
GC D C L VG +CE + +R N C+P S CL
Sbjct: 1396 RGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDN 1455
Query: 962 GKCHPLASCQSTSSGVWSCVCQEGY 986
CH + T + V+ C + +
Sbjct: 1456 FDCH-AGGRERTCNPVYEKYCADHF 1479
Score = 60.8 bits (146), Expect = 2e-08
Identities = 78/290 (26%), Positives = 102/290 (35%), Gaps = 77/290 (26%)
Query: 1950 CCKGYFGRDCQA-CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM----CWPGR 2004
C GY G +C+ PC + G C+D A C C G G CE+ C PG
Sbjct: 1110 CLPGYNGDNCEDDVDECASQPCQHGGSCIDLV-ARYLCSCPPGTLGVLCEINEDDCGPGP 1168
Query: 2005 ---FGPDCLP------------CGC----------SDHGQCDDGIT-------------G 2026
GP CL C C +D +C G G
Sbjct: 1169 PLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGG 1228
Query: 2027 SGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFC 2086
+CLC G++GP C Q VL + PC C+ + G G T C
Sbjct: 1229 GFRCLCHAGFSGPRC--QTVLSPCESQPCQHGGQCRPS---------PGPGGGLTFTCHC 1277
Query: 2087 KQDNGG--CAKVAR-CSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKM 2143
Q G C +VAR C + V CQ+ +G C C GL+G +C+
Sbjct: 1278 AQPFWGPRCERVARSCRELQCPVGVPCQQTPRGP--RCA----CPPGLSG-----PSCRS 1326
Query: 2144 ---TGPGKHKCECKSHYVGDGLNCEPEQL-PIDRCLQDNG----QCHADA 2185
+ PG C + G +C P L P RC G +C A A
Sbjct: 1327 FPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPA 1376
Score = 56.2 bits (134), Expect = 4e-07
Identities = 59/232 (25%), Positives = 74/232 (31%), Gaps = 55/232 (23%)
Query: 1876 GIDCLLIDPTLGGRCDTFTTFDASGEC---GSCVNTPSCPRWSKPKGVKQKCLYNLPF-- 1930
G CL G RC T + S C G C +P G+ C PF
Sbjct: 1229 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPG-----PGGGLTFTCHCAQPFWG 1283
Query: 1931 ---KRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECK 1987
+R CRE +Q P G CQ P GP C
Sbjct: 1284 PRCERVARSCRE-----LQCP------VGVPCQQTPRGP------------------RCA 1314
Query: 1988 CNTGFNGTACEM---CWPGRFGPDCLPCGCSDHGQCDDG-ITGSGQCLCETGWTGPSCDT 2043
C G +G +C PG C C G C + +C C GWTGP C+
Sbjct: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA 1374
Query: 2044 QAVLPAVCTPPCSAHATCK-ENNTCECNLDYEGDGITCTVVDFCKQDNGGCA 2094
A P V P A C+ + C+ + G C D G C+
Sbjct: 1375 PAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPG--------CGWDGGDCS 1418
Score = 54.3 bits (129), Expect = 2e-06
Identities = 78/327 (23%), Positives = 118/327 (36%), Gaps = 69/327 (21%)
Query: 1876 GIDCLLIDPTLGGRCDTFTTFDASGEC---GSCVNTPS---CPRWSKPKGVKQKC-LYNL 1928
G C ++ G +C T + + C G CV T + CP P + C + +L
Sbjct: 983 GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP----PGWSGRLCDIRSL 1038
Query: 1929 PFKRNLEGCRERCSLV-IQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECK 1987
P CRE + + +++ + C+ G C+D+ S+ C
Sbjct: 1039 P-------CREAAAQIGVRLEQLCQA-------------------GGQCVDEDSSH-YCV 1071
Query: 1988 CNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVL 2047
C G G+ CE P CL C G C G G C C G+ G +C+ +
Sbjct: 1072 CPEGRTGSHCEQ----EVDP-CLAQPCQHGGTCR-GYMGGYMCECLPGYNGDNCEDD--V 1123
Query: 2048 PAVCTPPCSAHATCKE---NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGT 2104
+ PC +C + C C G+ C + + RC GT
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTL--GVLCEINEDDCGPGPPLDSGPRCLHNGT 1181
Query: 2105 KVS------CSCQKGYKGDGHSC-TEIDPCADGLNGGCHEHAT--CKMTGPGKHKCECKS 2155
V C+C GY G C +I+ C +G CH T C G +C C +
Sbjct: 1182 CVDLVGGFRCTCPPGY--TGLRCEADINECR---SGACHAAHTRDCLQDPGGGFRCLCHA 1236
Query: 2156 HYVGDGLNCEPEQLPID-RCLQDNGQC 2181
+ G C+ P + + Q GQC
Sbjct: 1237 GF--SGPRCQTVLSPCESQPCQHGGQC 1261
Score = 45.4 bits (106), Expect = 7e-04
Identities = 69/264 (26%), Positives = 87/264 (32%), Gaps = 47/264 (17%)
Query: 1336 CCAGFFGPQCQ----PCPGNAQNVCFGNGICLD----GVNGTGVCECGEGFSGTACETCT 1387
C AGF GP+CQ PC C G C G T C C + F G CE
Sbjct: 1234 CHAGFSGPRCQTVLSPCESQP---CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVA 1290
Query: 1388 EGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN--ATTEDNCNGTCHTSAN 1445
+ C V C Q P G C C G G C + + N +C +A
Sbjct: 1291 RSCRELQCP-----VGVPCQQTPRGP-RCACPPGLSGPSCRSFPGSPPGASNASC-AAAP 1343
Query: 1446 CLTNSDGTAS-------CKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVC 1498
CL + C CA G+ G A A E+S +A C+ +R C
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA-APEVSEEPRCPRAACQAKRGDQR-C 1401
Query: 1499 TCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINV 1558
+ G G + C + G + E Q C PA +
Sbjct: 1402 DRECNSPGCG---WDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSP--------A 1450
Query: 1559 CLTKNGGCSEFAICNHTGQVERTC 1582
CL N C H G ERTC
Sbjct: 1451 CLYDNFDC-------HAGGRERTC 1467
Score = 41.6 bits (96), Expect = 0.010
Identities = 42/165 (25%), Positives = 58/165 (35%), Gaps = 36/165 (21%)
Query: 100 CCPGRWGPDC---------IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
C WGP C ++CP G RG C+C G G +C +
Sbjct: 1277 CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGP---------RCACPPGLSGPSCRSF 1327
Query: 151 --ADDNLFGPSCSSVCNCVHG-VCNSG-LDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
+ SC++ C+HG C L C C +TGP+C+ P AA E
Sbjct: 1328 PGSPPGASNASCAAA-PCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAP---AAAPEVSE 1383
Query: 207 NSRCSPSTEDENKLECKC-----LPNYRGDGKYC-----DPINPC 241
RC + + + +C P DG C DP C
Sbjct: 1384 EPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
>gi|26051243 tumor necrosis factor, alpha-induced protein 6 precursor
[Homo sapiens]
Length = 277
Score = 107 bits (266), Expect = 2e-22
Identities = 46/104 (44%), Positives = 62/104 (59%)
Query: 2194 DTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGR 2253
+ GV+H + G+YKLT+ +A+ C E +ATY QL A+K +H+C+AGW+ GR
Sbjct: 32 ERAAGVYHREARSGKYKLTYAEAKAVCEFEGGHLATYKQLEAARKIGFHVCAAGWMAKGR 91
Query: 2254 VAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMKDVNC 2297
V YP NCG G GI+DYG R N+SE WD +CY C
Sbjct: 92 VGYPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAKEC 135
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 107 bits (266), Expect = 2e-22
Identities = 108/373 (28%), Positives = 139/373 (37%), Gaps = 106/373 (28%)
Query: 642 NGRIYTLTGVLIPPSIVPILPHRCDETKREMKLGTCV--------SCSLVYWSRCPANSE 693
NG Y G P PH C T+ + G CV CS RCPA+
Sbjct: 327 NGTCYCEEGFTGEDCGKPTCPHAC-HTQGRCEEGQCVCDEGFAGVDCSE---KRCPADCH 382
Query: 694 PTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGN 751
RCV GR +C GF G DC + CP G CSG+
Sbjct: 383 NRG----RCV-DGRC------------------ECDDGFTGADCGELKCPNG----CSGH 415
Query: 752 GQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPR---CNKKCLCVHG---------TC 799
G+C NG C+C+EG+ G C PN R KC+C G +C
Sbjct: 416 GRCV-----NGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSC 470
Query: 800 NNRIDSDGACLTG--TCRDGSAGRLC-DKQTSACGPYVQFCHIHATCEYSNGTASCICKA 856
N G C+ G C DG G C D+Q + C C C+C+
Sbjct: 471 PNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCP------RDCSNRGLCV----DGQCVCED 520
Query: 857 GYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLL 916
G+ G C+E+ P C C+ CVC +G+ G +DC E C
Sbjct: 521 GFTGPD--CAELS-----CPNDCHGQGRCVNG-----QCVCHEGFMG--KDCKE-QRC-- 563
Query: 917 PSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSG 976
PS CH C+ +C C +GF G+DC SC C+ L C S
Sbjct: 564 PS--DCHGQGRCV-----DGQCICHEGF--TGLDCGQ-HSC---PSDCNNLGQCVSGR-- 608
Query: 977 VWSCVCQEGYEGD 989
C+C EGY G+
Sbjct: 609 ---CICNEGYSGE 618
Score = 98.6 bits (244), Expect = 7e-20
Identities = 78/264 (29%), Positives = 106/264 (40%), Gaps = 72/264 (27%)
Query: 728 CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
C +GF G DC++ CP N C G+C NGTC CEEGF G C + P+
Sbjct: 301 CDEGFTGEDCSELICP----NDCFDRGRCI-----NGTCYCEEGFTGEDCGKPTCPH--- 348
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEY 845
C+ + C G C C +G AG C ++ CH C
Sbjct: 349 -ACHTQGRCEEGQC-------------VCDEGFAGVDCSEKRCPAD-----CHNRGRCV- 388
Query: 846 SNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNG 905
C C G+ G C E+ P GCS + C+ CVC +G+T G
Sbjct: 389 ---DGRCECDDGFTGAD--CGELK-----CPNGCSGHGRCV-----NGQCVCDEGYT--G 431
Query: 906 RDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCH 965
DCS+ L CH C+ + +C C++GF+ G DC + SC CH
Sbjct: 432 EDCSQ-----LRCPNDCHSRGRCV-----EGKCVCEQGFK--GYDCSDM-SC---PNDCH 475
Query: 966 PLASCQSTSSGVWSCVCQEGYEGD 989
C + CVC +GY G+
Sbjct: 476 QHGRCVN-----GMCVCDDGYTGE 494
Score = 97.8 bits (242), Expect = 1e-19
Identities = 90/325 (27%), Positives = 123/325 (37%), Gaps = 90/325 (27%)
Query: 702 CVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLG 759
C G F + GC C G+ GP+C++ CPG C G+C D
Sbjct: 161 CSGRGNFSTEGCGCV-----------CEPGWKGPNCSEPECPGN----CHLRGRCID--- 202
Query: 760 GNGTCICEEGFQGSQCQFC---SDPNKYGPRCNKKCLCVHG----TCNNRI------DSD 806
G CIC++GF G C SD N G N C+C G C+ I +
Sbjct: 203 --GQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEH 260
Query: 807 GACLTG--TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTL 864
G C+ G C DG AG C+K + C+ C + C+C G+ G+
Sbjct: 261 GTCVDGLCVCHDGFAGDDCNKPLC-----LNNCYNRGRCVEN----ECVCDEGFTGED-- 309
Query: 865 CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHD 924
CSE+ + P C CI TC C++G+T G DC + P A CH
Sbjct: 310 CSEL-----ICPNDCFDRGRCI-----NGTCYCEEGFT--GEDCGKPT---CPHA--CHT 352
Query: 925 NASCLYVGPGQNECECKKGFRGNG-------IDCEPITSCLEQTGKCHP--------LAS 969
C + +C C +GF G DC C++ +C
Sbjct: 353 QGRC-----EEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELK 407
Query: 970 CQSTSSG-----VWSCVCQEGYEGD 989
C + SG CVC EGY G+
Sbjct: 408 CPNGCSGHGRCVNGQCVCDEGYTGE 432
Score = 84.3 bits (207), Expect = 1e-15
Identities = 95/354 (26%), Positives = 125/354 (35%), Gaps = 103/354 (29%)
Query: 1861 RIVQRELLFDLGVAYGIDCL-LIDPTL---GGRCDTFTTFDASGECGSCVNTPSCPRWSK 1916
R V+ E + D G G DC LI P GRC T + G G P+CP
Sbjct: 293 RCVENECVCDEGFT-GEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACH 351
Query: 1917 PKG--VKQKCLYNLPF-------KRNLEGCRERCSLVIQIPRCCKGYFGRDCQA--CPGG 1965
+G + +C+ + F KR C R V C G+ G DC CP G
Sbjct: 352 TQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
Query: 1966 PDAPCNNRGVCLDQYSATGECKCNTGFNGTACE-------------------MCWPGRFG 2006
C+ G C++ G+C C+ G+ G C +C G G
Sbjct: 412 ----CSGHGRCVN-----GQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKG 462
Query: 2007 PDC----LPCGCSDHGQC-------DDGITGS-------------------GQCLCETGW 2036
DC P C HG+C DDG TG GQC+CE G+
Sbjct: 463 YDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGF 522
Query: 2037 TGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEG-------------------DG 2077
TGP C + C C C N C C+ + G DG
Sbjct: 523 TGPDCAELS-----CPNDCHGQGRC-VNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDG 576
Query: 2078 ITCTVVDFCKQDNGGCAKVARCSQKGTKVS--CSCQKGYKGDGHSCTEIDPCAD 2129
F D G + + C+ G VS C C +GY G+ C+E+ P D
Sbjct: 577 QCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGE--DCSEVSPPKD 628
Score = 77.8 bits (190), Expect = 1e-13
Identities = 105/431 (24%), Positives = 137/431 (31%), Gaps = 137/431 (31%)
Query: 21 PAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTY 80
P G A D K LL+ E + +L +C G + G D R R
Sbjct: 107 PRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRG- 165
Query: 81 SLSLPGCRHICRKDYLQPRC----CPGRW------------------GPDC--IECPGGA 116
+ S GC +C + P C CPG G DC + CP
Sbjct: 166 NFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACP--- 222
Query: 117 GSPCNGRGSCAEGMEGNGTCSCQEGFGGTACE-------------TCAD----------- 152
S CN +G C NG C C EG+ G C TC D
Sbjct: 223 -SDCNDQGKCV-----NGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAG 276
Query: 153 DNLFGPSCSSVC----NCVHG--VCNSGLDGD-------------------GTCECYSAY 187
D+ P C + C CV VC+ G G+ GTC C +
Sbjct: 277 DDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGF 336
Query: 188 TGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICH 247
TG C KP A C RC +C C + G D CH
Sbjct: 337 TGEDCGKPTCPHA---CHTQGRCEEG-------QCVCDEGFAG----VDCSEKRCPADCH 382
Query: 248 PHAHCTYLGPNRHSCTCQEGYRGD--GQVCLPVDPCQINFGNCPTKSTVCK--YDG---- 299
C C C +G+ G G++ P + C G C VC Y G
Sbjct: 383 NRGRCV-----DGRCECDDGFTGADCGELKCP-NGCS-GHGRCVNGQCVCDEGYTGEDCS 435
Query: 300 ----PGQSH---------CECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRT 346
P H C C++ ++ G CS C +D CH++ C
Sbjct: 436 QLRCPNDCHSRGRCVEGKCVCEQGFK----GYDCSDMS-CPND--CHQHGRCV-----NG 483
Query: 347 ECICQKGYVGD 357
C+C GY G+
Sbjct: 484 MCVCDDGYTGE 494
Score = 76.3 bits (186), Expect = 4e-13
Identities = 96/372 (25%), Positives = 127/372 (34%), Gaps = 94/372 (25%)
Query: 1272 CDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTV 1331
C T + G C C G K C+ Y GR + +CV
Sbjct: 256 CSEEHGTCVDGLC-------VCHDGFAGDDCNKPLCLNNCYNRGRCV-----ENECV--- 300
Query: 1332 ITRECCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT-------- 1381
C GF G C CP N CF G C++G C C EGF+G
Sbjct: 301 ----CDEGFTGEDCSELICP----NDCFDRGRCINGT-----CYCEEGFTGEDCGKPTCP 347
Query: 1382 -ACET----------CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNA 1430
AC T C EG G+ C + C N+G DG C+CD G+ G C
Sbjct: 348 HACHTQGRCEEGQCVCDEGFAGVDCSEK-RCPADCHNRGRCVDGRCECDDGFTGADCGEL 406
Query: 1431 TTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAI---NACEISNGGC-SAKA 1486
+ C+G C+ C C G+ G C+ + N C S G C K
Sbjct: 407 KCPNGCSG----HGRCV-----NGQCVCDEGYTGED--CSQLRCPNDCH-SRGRCVEGKC 454
Query: 1487 DCKRTTPG-------------------RRVCTCKAGYTGDGIVCLEINPCLENHGGC-DK 1526
C++ G +C C GYTG+ + N G C D
Sbjct: 455 VCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDG 514
Query: 1527 NAECTQ--TGPNQAACNCLPAYTGDGKVCTLINVCLTKNGG--CSEF---AICNHTGQ-V 1578
C TGP+ A +C G G+ VC G C E + C+ G+ V
Sbjct: 515 QCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCV 574
Query: 1579 ERTCTCKPNYIG 1590
+ C C + G
Sbjct: 575 DGQCICHEGFTG 586
Score = 70.5 bits (171), Expect = 2e-11
Identities = 79/304 (25%), Positives = 98/304 (32%), Gaps = 95/304 (31%)
Query: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 1385
C G+ GP C CPGN C G C+DG C C +GF+G C
Sbjct: 176 CEPGWKGPNCSEPECPGN----CHLRGRCIDGQ-----CICDDGFTGEDCSQLACPSDCN 226
Query: 1386 -----------CTEGKYGIHCDQ-----ACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN 1429
C EG G C + CS HG C DG C C G+ G C+
Sbjct: 227 DQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTC-----VDGLCVCHDGFAGDDCNK 281
Query: 1430 ATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 1489
C C+ C+ N C C GF G C+ + I C + C
Sbjct: 282 PL----CLNNCYNRGRCVEN-----ECVCDEGFTGED--CSEL----ICPNDCFDRGRCI 326
Query: 1490 RTTPGRRVCTCKAGYTGDGI-------VCLEINPCLENHGGCDKN------------AEC 1530
T C C+ G+TG+ C C E CD+ A+C
Sbjct: 327 NGT-----CYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADC 381
Query: 1531 TQTGP-NQAACNCLPAYTGDGKVCTLINVC--LTKNGGCSEFAICNHTGQVERTCTCKPN 1587
G C C +TG C L GCS C V C C
Sbjct: 382 HNRGRCVDGRCECDDGFTGAD--------CGELKCPNGCSGHGRC-----VNGQCVCDEG 428
Query: 1588 YIGD 1591
Y G+
Sbjct: 429 YTGE 432
Score = 70.5 bits (171), Expect = 2e-11
Identities = 80/283 (28%), Positives = 98/283 (34%), Gaps = 72/283 (25%)
Query: 53 KCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLP-GCRHICRKDYLQPRCCPGRWGPDC-- 109
+C DG G G DC L P GC R Q C G G DC
Sbjct: 386 RCVDGRCECDDGFTGA-DCG--------ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQ 436
Query: 110 IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHG 169
+ CP + C+ RG C EG C C++GF G C + N C CV+G
Sbjct: 437 LRCP----NDCHSRGRCVEGK-----CVCEQGFKGYDCSDMSCPN----DCHQHGRCVNG 483
Query: 170 VC---------------------NSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENS 208
+C N GL DG C C +TG P+CA L CP +
Sbjct: 484 MCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTG-------PDCAELSCPND- 535
Query: 209 RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGY 268
C N +C C + G D CH C C C EG+
Sbjct: 536 -CHGQGRCVNG-QCVCHEGFMGK----DCKEQRCPSDCHGQGRCV-----DGQCICHEGF 584
Query: 269 RG--DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKE 309
G GQ P D C N G C + +C G S +C E
Sbjct: 585 TGLDCGQHSCPSD-CN-NLGQCVSGRCIC---NEGYSGEDCSE 622
Score = 70.1 bits (170), Expect = 3e-11
Identities = 85/311 (27%), Positives = 111/311 (35%), Gaps = 74/311 (23%)
Query: 85 PGCRHIC----RKDYLQPRCCPGRWGPDCIE--CPGGAGSPCNGRGSCAEGMEGNGTCSC 138
P C H C R + Q C G G DC E CP + C+ RG C +G C C
Sbjct: 344 PTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCP----ADCHNRGRCVDGR-----CEC 394
Query: 139 QEGFGGTACETCADDNLFGPSCSSVCNCVHG--VCNSGLDGD------------------ 178
+GF G C N CS CV+G VC+ G G+
Sbjct: 395 DDGFTGADCGELKCPN----GCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCV 450
Query: 179 -GTCECYSAYTGPKC-DKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDG---K 233
G C C + G C D P C ++ RC C C Y G+ +
Sbjct: 451 EGKCVCEQGFKGYDCSDMSCPND----CHQHGRCVNGM-------CVCDDGYTGEDCRDR 499
Query: 234 YCDPINPCLRKICHPHAHCT----YLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCP 289
C P + R +C C + GP+ +C G G+ C F
Sbjct: 500 QC-PRDCSNRGLC-VDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKD 557
Query: 290 TKSTVCKYDGPGQSHC---ECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRT 346
K C D GQ C +C H + F G+ C C SD C+ C + GR
Sbjct: 558 CKEQRCPSDCHGQGRCVDGQCICH-EGFT-GLDCGQHS-CPSD--CNNLGQCVS---GR- 608
Query: 347 ECICQKGYVGD 357
CIC +GY G+
Sbjct: 609 -CICNEGYSGE 618
Score = 65.1 bits (157), Expect = 9e-10
Identities = 75/303 (24%), Positives = 106/303 (34%), Gaps = 77/303 (25%)
Query: 1931 KRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAP--CNNRGVCLDQYSATG-ECK 1987
K L E +LV + C G Q G D C+ RG +S G C
Sbjct: 120 KELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRG----NFSTEGCGCV 175
Query: 1988 CNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVL 2047
C G+ G C P+C P C G+C DG QC+C+ G+TG C A
Sbjct: 176 CEPGWKGPNCSE-------PEC-PGNCHLRGRCIDG-----QCICDDGFTGEDCSQLA-- 220
Query: 2048 PAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDF-CKQDNGGCAK----------- 2095
C C+ C N C C Y G + + C +++G C
Sbjct: 221 ---CPSDCNDQGKC-VNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAG 276
Query: 2096 --------VARCSQKGTKV--SCSCQKGYKGDGHSCTEI---DPCADG---LNGGCHEHA 2139
+ C +G V C C +G+ G+ C+E+ + C D +NG C+
Sbjct: 277 DDCNKPLCLNNCYNRGRCVENECVCDEGFTGE--DCSELICPNDCFDRGRCINGTCYCEE 334
Query: 2140 TCKMTGPGKHKCECKSHYVG-------------DGLNCEPEQLPIDRCLQDNGQCHADAK 2186
GK C H G G++C ++ P D CH +
Sbjct: 335 GFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPAD--------CHNRGR 386
Query: 2187 CVD 2189
CVD
Sbjct: 387 CVD 389
Score = 64.3 bits (155), Expect = 1e-09
Identities = 45/145 (31%), Positives = 59/145 (40%), Gaps = 39/145 (26%)
Query: 728 CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
C GF GPDC + CP N C G G+C NG C+C EGF G C+ P+
Sbjct: 518 CEDGFTGPDCAELSCP----NDCHGQGRCV-----NGQCVCHEGFMGKDCKEQRCPSD-- 566
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEY 845
C+ + CV G C C +G G C + + C+ C
Sbjct: 567 --CHGQGRCVDGQC-------------ICHEGFTGLDCGQHSCPSD-----CNNLGQCV- 605
Query: 846 SNGTASCICKAGYEGDGTLCSEMDP 870
+ CIC GY G+ CSE+ P
Sbjct: 606 ---SGRCICNEGYSGED--CSEVSP 625
Score = 61.6 bits (148), Expect = 9e-09
Identities = 59/211 (27%), Positives = 79/211 (37%), Gaps = 47/211 (22%)
Query: 1271 RCDNNDTTIIRGRCRTCSSELTCPFGTKSLGN-EKRRCIYTSYFMGRRTLFIGC------ 1323
RC N G S+L CP S G + +C+ F G + C
Sbjct: 417 RCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQ 476
Query: 1324 QPKCVRTVITRECCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
+CV + C G+ G C+ CP + C G+C+DG C C +GF+G
Sbjct: 477 HGRCVNGMCV--CDDGYTGEDCRDRQCPRD----CSNRGLCVDGQ-----CVCEDGFTGP 525
Query: 1382 ACE-------------------TCTEGKYGIHC-DQAC-SCVHGRCNQGPLGDGSCDCDV 1420
C C EG G C +Q C S HG QG DG C C
Sbjct: 526 DCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHG---QGRCVDGQCICHE 582
Query: 1421 GWRGVHCDNATTEDNCN--GTCHTSANCLTN 1449
G+ G+ C + +CN G C S C+ N
Sbjct: 583 GFTGLDCGQHSCPSDCNNLGQC-VSGRCICN 612
Score = 57.8 bits (138), Expect = 1e-07
Identities = 60/202 (29%), Positives = 78/202 (38%), Gaps = 39/202 (19%)
Query: 1404 GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
GR N G G C C+ GW+G +C +E C G CH C+ DG C C GF
Sbjct: 163 GRGNFSTEGCG-CVCEPGWKGPNC----SEPECPGNCHLRGRCI---DG--QCICDDGFT 212
Query: 1464 GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI---VCLEINPCLEN 1520
G C+ + AC C+ + C VC C GY G +C PC E
Sbjct: 213 GED--CSQL-ACP---SDCNDQGKCV-----NGVCICFEGYAGADCSREICPV--PCSEE 259
Query: 1521 HGGCDKNAECTQTGPNQAACN---CLPAYTGDGKVCTLINVCLTKNG----GCSEFAI-- 1571
HG C G CN CL G+ + N C+ G CSE
Sbjct: 260 HGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGR--CVENECVCDEGFTGEDCSELICPN 317
Query: 1572 -CNHTGQ-VERTCTCKPNYIGD 1591
C G+ + TC C+ + G+
Sbjct: 318 DCFDRGRCINGTCYCEEGFTGE 339
Score = 52.0 bits (123), Expect = 7e-06
Identities = 38/123 (30%), Positives = 46/123 (37%), Gaps = 40/123 (32%)
Query: 100 CCPGRWGPDCIE--CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC--ETCADDNL 155
C G GPDC E CP + C+G+G C NG C C EGF G C + C D
Sbjct: 518 CEDGFTGPDCAELSCP----NDCHGQGRCV-----NGQCVCHEGFMGKDCKEQRCPSD-- 566
Query: 156 FGPSCSSVCNCVHG--VCNSGLDG-------------------DGTCECYSAYTGPKCDK 194
C CV G +C+ G G G C C Y+G C +
Sbjct: 567 ----CHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSE 622
Query: 195 PIP 197
P
Sbjct: 623 VSP 625
Score = 50.1 bits (118), Expect = 3e-05
Identities = 37/117 (31%), Positives = 44/117 (37%), Gaps = 31/117 (26%)
Query: 1336 CCAGFFGPQCQP--CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-------- 1385
C GF GP C CP N C G G C++G C C EGF G C+
Sbjct: 518 CEDGFTGPDCAELSCP----NDCHGQGRCVNGQ-----CVCHEGFMGKDCKEQRCPSDCH 568
Query: 1386 -----------CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT 1431
C EG G+ C Q SC N G G C C+ G+ G C +
Sbjct: 569 GQGRCVDGQCICHEGFTGLDCGQH-SCPSDCNNLGQCVSGRCICNEGYSGEDCSEVS 624
Score = 43.9 bits (102), Expect = 0.002
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 11/56 (19%)
Query: 728 CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP 781
C +GF G DC Q CP + C+ GQC +G CIC EG+ G C S P
Sbjct: 580 CHEGFTGLDCGQHSCP----SDCNNLGQCV-----SGRCICNEGYSGEDCSEVSPP 626
Score = 35.0 bits (79), Expect = 0.95
Identities = 32/111 (28%), Positives = 44/111 (39%), Gaps = 20/111 (18%)
Query: 1289 SELTCPFGTKSLGN-EKRRCIYTSYFMGRRTLFIGC------QPKCVRTVITRECCAGFF 1341
+EL+CP G +C+ FMG+ C Q +CV C GF
Sbjct: 528 AELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCI--CHEGFT 585
Query: 1342 GPQC--QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGK 1390
G C CP + N+ G C+ +G C C EG+SG C + K
Sbjct: 586 GLDCGQHSCPSDCNNL----GQCV-----SGRCICNEGYSGEDCSEVSPPK 627
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 105 bits (261), Expect = 7e-22
Identities = 95/330 (28%), Positives = 138/330 (41%), Gaps = 34/330 (10%)
Query: 675 GTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKC-CKGFY 733
G CV+ + C A + T CV GC +C T +C C Y
Sbjct: 1127 GQCVNVIGAFQCSCHAGFQSTP-DRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGY 1185
Query: 734 G--PDCNQCPGGFSNPCSGN------GQCADSLGGNGTCICEEGFQGS-QCQFCSDPNKY 784
PD C + C N G C + GG+ C+C +GF + + C D ++
Sbjct: 1186 SLMPDGRACAD--VDECEENPRVCDQGHCTNMPGGH-RCLCYDGFMATPDMRTCVDVDE- 1241
Query: 785 GPRCN-KKCLCVHGTCNNRIDSDGA-CLTG-TCRDGSAGRLCDKQTSACGPYVQFCHIHA 841
C+ +C+HG C N S C G R G+ G C C C HA
Sbjct: 1242 ---CDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATG--CS-DVDECEVGGHNCDSHA 1295
Query: 842 TCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW 901
+C G+ SC C G+ GDG C ++D C CS +C+ G++ C C+QG+
Sbjct: 1296 SCLNIPGSFSCRCLPGWVGDGFECHDLDECVS-QEHRCSPRGDCLNV-PGSYRCTCRQGF 1353
Query: 902 TGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLE 959
G+G C + + C + C DN CL PG CEC+ GF + C+ + C +
Sbjct: 1354 AGDGFFCEDRDECA-ENVDLC-DNGQCLNA-PGGYRCECEMGFDPTEDHRACQDVDECAQ 1410
Query: 960 QTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
G SC++ G++ C+C GYE D
Sbjct: 1411 --GNLCAFGSCENLP-GMFRCICNGGYELD 1437
Score = 104 bits (259), Expect = 1e-21
Identities = 83/295 (28%), Positives = 122/295 (41%), Gaps = 36/295 (12%)
Query: 709 GSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEE 768
GS K C T K C D ++C S+ +GQC + +G C C
Sbjct: 1092 GSYKCQCPPGHELTAKGTAC------EDIDEC--SLSDGLCPHGQCVNVIGAF-QCSCHA 1142
Query: 769 GFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSA----GRLCD 824
GFQ S P++ G +C +G C+ + +C G + GR C
Sbjct: 1143 GFQ-------STPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRAC- 1194
Query: 825 KQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEG--DGTLCSEMDPCTGLTPGGCSRN 882
C + C C G C+C G+ D C ++D C L P C +
Sbjct: 1195 ADVDECEENPRVCD-QGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECD-LNPHICL-H 1251
Query: 883 AECIKTGTGTHTCVCQQGWT--GNGRDCSEINNCLLPSAGG--CHDNASCLYVGPGQNEC 938
+C T G+ C CQ G+ CS+++ C GG C +ASCL + PG C
Sbjct: 1252 GDCENT-KGSFVCHCQLGYMVRKGATGCSDVDEC---EVGGHNCDSHASCLNI-PGSFSC 1306
Query: 939 ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLC 993
C G+ G+G +C + C+ Q +C P C + G + C C++G+ GDGF C
Sbjct: 1307 RCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNV-PGSYRCTCRQGFAGDGFFC 1360
Score = 98.6 bits (244), Expect = 7e-20
Identities = 81/283 (28%), Positives = 114/283 (40%), Gaps = 29/283 (10%)
Query: 1322 GCQPKCVRTVITRECCAGFF------GPQCQPCPGNAQN--VCFGNGICLDGVNGTGVCE 1373
GC C+ T + C G G C +N VC G C + + G C
Sbjct: 1165 GCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVC-DQGHCTN-MPGGHRCL 1222
Query: 1374 CGEGFSGTA-CETCTEGKYGIHCD-QACSCVHGRCNQGPLGDGSCDCDVGWR----GVHC 1427
C +GF T TC + CD C+HG C + G C C +G+ C
Sbjct: 1223 CYDGFMATPDMRTCVDVD---ECDLNPHICLHGDC-ENTKGSFVCHCQLGYMVRKGATGC 1278
Query: 1428 DNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKAD 1487
+ + C + A+CL N G+ SC+C G+ G+G C ++ C CS + D
Sbjct: 1279 SDVDECEVGGHNCDSHASCL-NIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGD 1337
Query: 1488 CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAY- 1546
C PG CTC+ G+ GDG C + + C EN CD N +C P C C +
Sbjct: 1338 CLNV-PGSYRCTCRQGFAGDGFFCEDRDECAENVDLCD-NGQCL-NAPGGYRCECEMGFD 1394
Query: 1547 -TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
T D + C ++ C G F C + + R C C Y
Sbjct: 1395 PTEDHRACQDVDEC--AQGNLCAFGSCENLPGMFR-CICNGGY 1434
Score = 97.8 bits (242), Expect = 1e-19
Identities = 101/346 (29%), Positives = 136/346 (39%), Gaps = 48/346 (13%)
Query: 666 DETKREMKL---GTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNAT 722
DE R+ L GTC + Y +CP E TA T C SL G +
Sbjct: 1073 DECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGT-ACEDIDEC-SLSDGLCPHGQCV 1130
Query: 723 VKIP----KCCKGFYG-PDCNQCPGGFSNPCS-GNGQC---ADSLGGNGTCICEEGFQ-- 771
I C GF PD C N C NG C + G+ C C +G+
Sbjct: 1131 NVIGAFQCSCHAGFQSTPDRQGCVD--INECRVQNGGCDVHCINTEGSYRCSCGQGYSLM 1188
Query: 772 --GSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAG----RLCDK 825
G C D + PR +C G C N + CL C DG R C
Sbjct: 1189 PDGRACADV-DECEENPR-----VCDQGHCTN-MPGGHRCL---CYDGFMATPDMRTC-V 1237
Query: 826 QTSACGPYVQFCHIHATCEYSNGTASCICKAGY--EGDGTLCSEMDPCTGLTPGG--CSR 881
C C +H CE + G+ C C+ GY T CS++D C GG C
Sbjct: 1238 DVDECDLNPHIC-LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECE---VGGHNCDS 1293
Query: 882 NAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECK 941
+A C+ G+ +C C GW G+G +C +++ C+ C CL V PG C C+
Sbjct: 1294 HASCLNI-PGSFSCRCLPGWVGDGFECHDLDECV-SQEHRCSPRGDCLNV-PGSYRCTCR 1350
Query: 942 KGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE 987
+GF G+G CE C E C C + G + C C+ G++
Sbjct: 1351 QGFAGDGFFCEDRDECAENVDLCDN-GQCLNAPGG-YRCECEMGFD 1394
Score = 92.8 bits (229), Expect = 4e-18
Identities = 69/241 (28%), Positives = 95/241 (39%), Gaps = 24/241 (9%)
Query: 123 RGSCAEGMEGNGTCSCQEGFGGTA-CETCADDNLFGPSCSSVCN-CVHGVCNSGLDGDGT 180
+G C M G C C +GF T TC D + C + C+HG C + G
Sbjct: 1209 QGHCTN-MPGGHRCLCYDGFMATPDMRTCVDVD----ECDLNPHICLHGDCEN-TKGSFV 1262
Query: 181 CECYSAYT---GPKCDKPIPEC--AALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYC 235
C C Y G + EC C ++ C C+CLP + GDG C
Sbjct: 1263 CHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC---LNIPGSFSCRCLPGWVGDGFEC 1319
Query: 236 DPINPCLRKI--CHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKST 293
++ C+ + C P C + P + CTC++G+ GDG C D C N C
Sbjct: 1320 HDLDECVSQEHRCSPRGDCLNV-PGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNGQC 1378
Query: 294 VCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKG 353
+ + PG CEC+ + C D C N C +C + PG CIC G
Sbjct: 1379 L---NAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLC-AFGSCENL-PGMFRCICNGG 1433
Query: 354 Y 354
Y
Sbjct: 1434 Y 1434
Score = 91.7 bits (226), Expect = 9e-18
Identities = 98/390 (25%), Positives = 137/390 (35%), Gaps = 81/390 (20%)
Query: 1270 NRCDNNDTTIIRGRCRTCSSELTCPF-GTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCV 1328
N C G CR C G +L ++R C T R + + Q CV
Sbjct: 988 NECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNC--TDIDECRISPDLCGQGTCV 1045
Query: 1329 RTVITREC-C-----AGFF-GPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFS-- 1379
T + EC C +GF C A++ G +G+ C+C G
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELT 1105
Query: 1380 --GTACETCTEGKYGIHCDQACS-----CVHGRCNQGPLGDGSCDCDVGWRG-------- 1424
GTACE E CS C HG+C +G C C G++
Sbjct: 1106 AKGTACEDIDE----------CSLSDGLCPHGQC-VNVIGAFQCSCHAGFQSTPDRQGCV 1154
Query: 1425 -------------VHCDNATTEDNCN-----------GTCHTSANC-----------LTN 1449
VHC N C+ C C TN
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTN 1214
Query: 1450 SDGTASCKCAAGFQGNGTI--CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT-- 1505
G C C GF + C ++ C+++ C DC+ T G VC C+ GY
Sbjct: 1215 MPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC-LHGDCENTK-GSFVCHCQLGYMVR 1272
Query: 1506 GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGG 1565
C +++ C CD +A C P +C CLP + GDG C ++ C+++
Sbjct: 1273 KGATGCSDVDECEVGGHNCDSHASCLNI-PGSFSCRCLPGWVGDGFECHDLDECVSQEHR 1331
Query: 1566 CSEFAICNHTGQVERTCTCKPNYIGDGFTC 1595
CS C + R CTC+ + GDGF C
Sbjct: 1332 CSPRGDCLNVPGSYR-CTCRQGFAGDGFFC 1360
Score = 91.3 bits (225), Expect = 1e-17
Identities = 96/397 (24%), Positives = 146/397 (36%), Gaps = 59/397 (14%)
Query: 11 LGLVVQNFCSPAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPDGYTMITS--GSVGV 68
LG ++F S C L CR+ + C G+ + +
Sbjct: 970 LGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDI 1029
Query: 69 RDCRYTFEV--RTYSLSLPGCRHICRKDYLQPRCCPGRWG-----PDCIECPGGAGSPCN 121
+CR + ++ + ++ PG + C PG +C++ A P
Sbjct: 1030 DECRISPDLCGQGTCVNTPGS--------FECECFPGYESGFMLMKNCMDVDECARDPLL 1081
Query: 122 GRGSCAEGMEGNGTCSCQEGFG----GTACETCADDNLFGPSCSSVCNCVHGVCNSGLDG 177
RG +G+ C C G GTACE + +L S C HG C + + G
Sbjct: 1082 CRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSL------SDGLCPHGQCVNVI-G 1134
Query: 178 DGTCECYSAYTGPKCDK---PIPECAALLCPENSRCSPST-EDENKLECKCLPNYR--GD 231
C C++ + + I EC +N C E C C Y D
Sbjct: 1135 AFQCSCHAGFQSTPDRQGCVDINECRV----QNGGCDVHCINTEGSYRCSCGQGYSLMPD 1190
Query: 232 GKYCDPINPCLR--KICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCLPVDPCQIN--- 284
G+ C ++ C ++C HCT + P H C C +G+ D + C+ VD C +N
Sbjct: 1191 GRACADVDECEENPRVCD-QGHCTNM-PGGHRCLCYDGFMATPDMRTCVDVDECDLNPHI 1248
Query: 285 --FGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICK-SDNPCHRNANCTTV 341
G+C G C C+ Y GCS D C+ + C +A+C +
Sbjct: 1249 CLHGDCENTK--------GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNI 1300
Query: 342 APGRTECICQKGYVGDGLTCYGNIMERLRELNTEPRG 378
PG C C G+VGDG C+ +E PRG
Sbjct: 1301 -PGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG 1336
Score = 76.6 bits (187), Expect = 3e-13
Identities = 86/350 (24%), Positives = 119/350 (34%), Gaps = 109/350 (31%)
Query: 729 CKGFYGPDCNQCPGGF------------SNPCSG------NGQCADSLGGNGTCICEEGF 770
CK G CP G N C NG+C ++ G+ C C+EGF
Sbjct: 2225 CKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVNT-AGSFRCDCDEGF 2283
Query: 771 QGS----QCQ-------------------------------FCSDPNKYGPRC------- 788
Q S +C C +GPRC
Sbjct: 2284 QPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPG 2343
Query: 789 ----NKKC---------------------LCVHGTCNNRIDSDGA-CLTGTCRDGSAGRL 822
K C LC HG C N + S C G D +A
Sbjct: 2344 TSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Query: 823 CDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGY--EGDGTLCSEMDPCTGLTPGGCS 880
D C + C C+ + G+ C C GY E DG C ++D CT
Sbjct: 2404 LD--MDECSQVPKPCTF--LCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSR-----Q 2454
Query: 881 RNAE--CIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNEC 938
N + C+ T G TC C G+T + + C + + C G C + C + PG C
Sbjct: 2455 HNCQFLCVNT-VGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCGAHGHC-HNTPGSFRC 2511
Query: 939 ECKKGFR--GNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
EC +GF +G CE + C + +C CQ+ G + C C +G+
Sbjct: 2512 ECHQGFTLVSSGHGCEDVNEC-DGPHRCQ--HGCQNQLGG-YRCSCPQGF 2557
Score = 75.9 bits (185), Expect = 5e-13
Identities = 101/388 (26%), Positives = 133/388 (34%), Gaps = 92/388 (23%)
Query: 686 SRCPANSEPTALFTHRCVYSGR-FGSLKSGC----------ARYCNATVKIPKCCKGFYG 734
SRC N + +L + C G +GS C AR T C+ F G
Sbjct: 819 SRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPG 878
Query: 735 PDCN------------QCPGGFSNPCSGN----------------GQCADSLGGN---GT 763
N +CP G SG +C +L G
Sbjct: 879 VCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDV 938
Query: 764 CICEEG-FQGSQCQFCSDPN--KYGPRCNK--------------------KC-----LCV 795
C C G G +C+ C DP ++ C + +C LC
Sbjct: 939 CCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCT 998
Query: 796 HGTCNNRIDS-DGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCIC 854
HGTC N + S AC G D D P C TC + G+ C C
Sbjct: 999 HGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISP--DLCG-QGTCVNTPGSFECEC 1055
Query: 855 KAGYEGDGTL---CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG--WTGNGRDCS 909
GYE L C ++D C P C R C T G++ C C G T G C
Sbjct: 1056 FPGYESGFMLMKNCMDVDEC-ARDPLLC-RGGTCTNT-DGSYKCQCPPGHELTAKGTACE 1112
Query: 910 EINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRG--NGIDCEPITSCLEQTGKCHPL 967
+I+ C L + G + C+ V G +C C GF+ + C I C Q G C
Sbjct: 1113 DIDECSL--SDGLCPHGQCVNV-IGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCD-- 1167
Query: 968 ASCQSTSSGVWSCVCQEGYE--GDGFLC 993
C +T G + C C +GY DG C
Sbjct: 1168 VHCINT-EGSYRCSCGQGYSLMPDGRAC 1194
Score = 75.9 bits (185), Expect = 5e-13
Identities = 82/308 (26%), Positives = 119/308 (38%), Gaps = 50/308 (16%)
Query: 1889 RCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIP 1948
+C F ++ + CV+ C + G C+ N EG RCS
Sbjct: 1137 QCSCHAGFQSTPDRQGCVDINECR--VQNGGCDVHCI-------NTEGSY-RCS------ 1180
Query: 1949 RCCKGY-FGRDCQACPGGPDAPCNNRGVCLDQYSATG-----ECKCNTGFNGTACEMCWP 2002
C +GY D +AC + N R VC DQ T C C GF T
Sbjct: 1181 -CGQGYSLMPDGRACADVDECEENPR-VC-DQGHCTNMPGGHRCLCYDGFMATPDMRTCV 1237
Query: 2003 GRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWT---GPSCDTQAVLPAVCTPPCSAHA 2059
D P C HG C++ GS C C+ G+ G + + V C +HA
Sbjct: 1238 DVDECDLNPHICL-HGDCEN-TKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHA 1295
Query: 2060 TCKE---NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG 2116
+C + +C C + GDG C +D C C+ C C+C++G+ G
Sbjct: 1296 SCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 2117 DGHSCTEIDPCADGL----NGGCHEHATCKMTGPGKHKCECKSHY--VGDGLNCEPEQLP 2170
DG C + D CA+ + NG C + PG ++CEC+ + D C+
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQC-------LNAPGGYRCECEMGFDPTEDHRACQ----D 1404
Query: 2171 IDRCLQDN 2178
+D C Q N
Sbjct: 1405 VDECAQGN 1412
Score = 73.6 bits (179), Expect = 2e-12
Identities = 77/280 (27%), Positives = 107/280 (38%), Gaps = 32/280 (11%)
Query: 736 DCNQCPG---GFS--NPCSGNGQCADS--LGGNGTCICEEGFQGSQCQFCSDPNKYGPRC 788
+C PG GF C +CA L GTC +G QC + G C
Sbjct: 1052 ECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC 1111
Query: 789 NK--KC-----LCVHGTCNNRIDS-DGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH 840
+C LC HG C N I + +C G + R + C C +H
Sbjct: 1112 EDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGF--QSTPDRQGCVDINECRVQNGGCDVH 1169
Query: 841 ATCEYSNGTASCICKAGYE--GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQ 898
C + G+ C C GY DG C+++D C P C + C G H C+C
Sbjct: 1170 --CINTEGSYRCSCGQGYSLMPDGRACADVDECEE-NPRVCDQG-HCTNM-PGGHRCLCY 1224
Query: 899 QGW--TGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPI 954
G+ T + R C +++ C L H + G C C+ G+ R C +
Sbjct: 1225 DGFMATPDMRTCVDVDECDLNPHICLHGDCENT---KGSFVCHCQLGYMVRKGATGCSDV 1281
Query: 955 TSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCY 994
C C ASC + G +SC C G+ GDGF C+
Sbjct: 1282 DECEVGGHNCDSHASCLNIP-GSFSCRCLPGWVGDGFECH 1320
Score = 70.9 bits (172), Expect = 2e-11
Identities = 70/271 (25%), Positives = 95/271 (35%), Gaps = 54/271 (19%)
Query: 100 CCPGR--WGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
CC G WGP C CP S C G G TA D+
Sbjct: 2325 CCGGGRGWGPRCELCPLPGTSAYRKL--------------CPHGSGYTAEGRDVDE---- 2366
Query: 158 PSCSSVCN-CVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS----P 212
C + + C HG C + L G C C + YT P+ A C + CS P
Sbjct: 2367 --CRMLAHLCAHGECINSL-GSFRCHCQAGYT--------PDATATTCLDMDECSQVPKP 2415
Query: 213 ST----EDENKLECKCLPNY--RGDGKYCDPINPCLRKICHPHAHCTYLGPNR---HSCT 263
T + C C Y DG+ C ++ C + +C +L N +C
Sbjct: 2416 CTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSR----QHNCQFLCVNTVGAFTCR 2471
Query: 264 CQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMT 323
C G+ Q C D C G C ++ PG CEC + + G GC
Sbjct: 2472 CPPGFTQHHQACFDNDECSAQPGPCGAHGHC--HNTPGSFRCECHQGFTLVSSGHGCE-- 2527
Query: 324 DICKSDNPCHRNANCTTVAPGRTECICQKGY 354
D+ + D P HR + G C C +G+
Sbjct: 2528 DVNECDGP-HRCQHGCQNQLGGYRCSCPQGF 2557
Score = 70.1 bits (170), Expect = 3e-11
Identities = 100/408 (24%), Positives = 142/408 (34%), Gaps = 82/408 (20%)
Query: 1824 VDLPTSTAWKTLQGSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDC--LL 1881
+D T W +Q S V L G + R E LG A+G C
Sbjct: 805 LDSTKGTCWLKIQESRCEVN-----------LQGASLR---SECCATLGAAWGSPCERCE 850
Query: 1882 IDPTL--GGRCDTFTTFDASGEC---------GSCVNTPSCPRWSKPKGVKQKCLYNLPF 1930
IDP G T T D EC G CVNT R P+G+ L
Sbjct: 851 IDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCV 910
Query: 1931 KRNLEGC-----RERCSLVI----QIPRCC---KGYFGRDCQACPGGPDAPCNNRGVCLD 1978
LE C + C + + ++ CC +G +C+ACP D
Sbjct: 911 DVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACP--------------D 956
Query: 1979 QYSATGECKCNTGFNGTACEMCWPGRFGPDCLPC----GCSDHGQCDDGITGSGQCLCET 2034
S C G + + F D C G HG C + + GS C C
Sbjct: 957 PESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTV-GSFHCACAG 1015
Query: 2035 GWTGPSCDTQAVLPAVC--TPPCSAHATCKE---NNTCECNLDYEGDGI---TCTVVDFC 2086
G+ + + C +P TC + CEC YE + C VD C
Sbjct: 1016 GFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDVDEC 1075
Query: 2087 KQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADGLNGGCHEHATCKMT 2144
+D C + C+ C C G++ G +C +ID C+ L+ G H C +
Sbjct: 1076 ARDPLLC-RGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECS--LSDGLCPHGQC-VN 1131
Query: 2145 GPGKHKCECKSHYVGDGLNCEPEQ---LPIDRCLQDNGQCHADAKCVD 2189
G +C C + G P++ + I+ C NG C D C++
Sbjct: 1132 VIGAFQCSCHA-----GFQSTPDRQGCVDINECRVQNGGC--DVHCIN 1172
Score = 68.6 bits (166), Expect = 8e-11
Identities = 85/354 (24%), Positives = 127/354 (35%), Gaps = 63/354 (17%)
Query: 675 GTCVSCSLVYWSRCPANSEPT-----ALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCC 729
G CV+ Y RC + T + C+ SG L R N C
Sbjct: 461 GDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHL----GRCVNTEGSFQCVC 516
Query: 730 KGFY--GPDCNQCPGGFSNPCSGNGQCADSL----GGNGTCICEEGFQ-GSQCQFCSDPN 782
+ PD C N C+ + C + + G+ +C+C+ GF +C D +
Sbjct: 517 NAGFELSPDGKNCVD--HNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDID 574
Query: 783 KYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLC--DKQTSACGPYVQFCHIH 840
+ C +CV+G C N S G G+ GR+C S C ++
Sbjct: 575 E----CQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCA 630
Query: 841 ATCEYSNGTASCICKAGYEGDG---TLCSEMDPC---------TGLTPGG-----CSRNA 883
+ + C C G G LC D G+T G C+ +
Sbjct: 631 RPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDP 690
Query: 884 ECIKTGT-----GTHTCVCQQGWT--GNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQN 936
E G G++ CVC G+ +G+DC++++ C L S DN C PG
Sbjct: 691 EVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSL--LCDNGWC-QNSPGSY 747
Query: 937 ECECKKGFR--GNGIDCEPITSCLEQ---TGKCHPLASCQSTSSGVWSCVCQEG 985
C C GF + C+ + CL +G C LA G ++C C G
Sbjct: 748 SCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLA-------GSYTCKCGPG 794
Score = 67.4 bits (163), Expect = 2e-10
Identities = 72/298 (24%), Positives = 106/298 (35%), Gaps = 57/298 (19%)
Query: 1336 CCA--GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
CC+ +G +C+ CP + + +C G GF A G+
Sbjct: 940 CCSIGAVWGVECEACPDP------------ESLEFASLCPRGLGF---ASRDFLSGRPFY 984
Query: 1394 HCDQACS-----CVHGRCNQGPLGDGSCDCDVGWR-GVHCDNATTEDNCN--------GT 1439
C C HG C + +G C C G+ N T D C GT
Sbjct: 985 KDVNECKVFPGLCTHGTC-RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGT 1043
Query: 1440 CHTSANCLTNSDGTASCKCAAGFQGNGTI---CTAINACE----ISNGGCSAKADCKRTT 1492
C N+ G+ C+C G++ + C ++ C + GG D
Sbjct: 1044 C-------VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTD----- 1091
Query: 1493 PGRRVCTCKAGY--TGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDG 1550
G C C G+ T G C +I+ C + G C G Q +C+ T D
Sbjct: 1092 -GSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDR 1150
Query: 1551 KVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNPK 1608
+ C IN C +NGGC I N G +C + + DG C + E +NP+
Sbjct: 1151 QGCVDINECRVQNGGCDVHCI-NTEGSYRCSCGQGYSLMPDGRAC--ADVDECEENPR 1205
Score = 67.4 bits (163), Expect = 2e-10
Identities = 78/303 (25%), Positives = 117/303 (38%), Gaps = 46/303 (15%)
Query: 712 KSGCARYCNAT--------VKIPKCCKGFYGPDCNQCPG-GFSNPCSGNGQCADSLGGNG 762
KS C R+ N T V CC C+ G ++ PC C + +
Sbjct: 1650 KSVCFRHYNGTCQNELAFNVTRKMCC-------CSYNIGQAWNRPCEA---CPTPISPDY 1699
Query: 763 TCICEEGFQGSQCQFCSDPNKYGPRCNKKC-----LCVHGTCNNRIDSDGACLTGTCRDG 817
+C G F +D + P +C +C +G C N+I S
Sbjct: 1700 QILCGNQAPG----FLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYN 1755
Query: 818 SAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYE-GDGTLCSEMDPCTGLTP 876
S C+ CG C +A C G+ C C GY+ G C + C + P
Sbjct: 1756 SILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREI-P 1813
Query: 877 GGCSRNAECIKTGTGTHTCVCQQGWTGNGRD--CSEINNCLLPSAGGCHDNASCLYVGPG 934
CS + +C+ T G++ C+C +G+ + C +I+ C G N +C + G
Sbjct: 1814 NVCS-HGDCMDT-EGSYMCLCHRGFQASADQTLCMDIDECDRQPCG----NGTCKNI-IG 1866
Query: 935 QNECECKKGF--RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE--GDG 990
C C GF NG DC C G+ C +T +G + C+CQ+G+E DG
Sbjct: 1867 SYNCLCFPGFVVTHNG-DCVDFDECTTLVGQVCRFGHCLNT-AGSFHCLCQDGFELTADG 1924
Query: 991 FLC 993
C
Sbjct: 1925 KNC 1927
Score = 66.6 bits (161), Expect = 3e-10
Identities = 69/258 (26%), Positives = 99/258 (38%), Gaps = 42/258 (16%)
Query: 1350 GNAQNVCFGNGICLDGVNGTGVCECGEGFSGT----ACETCTE-GKYGIHCDQACSCVHG 1404
G +C NGIC++ + G+ CEC GF+ ACE E G C Q C++
Sbjct: 1726 GEIPAIC-ANGICINQI-GSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINI 1783
Query: 1405 RCNQGPLGDGSCDCDVGWR---GVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAG 1461
G C C G++ G C C + +C+ +++G+ C C G
Sbjct: 1784 P------GSYRCKCTRGYKLSPGGACVGRNECREIPNVC-SHGDCM-DTEGSYMCLCHRG 1835
Query: 1462 FQGNG--TICTAINACE---ISNGGCSAKADCKRTTPGRRVCTCKAGYT----GDGIVCL 1512
FQ + T+C I+ C+ NG C + G C C G+ GD C+
Sbjct: 1836 FQASADQTLCMDIDECDRQPCGNGTC-------KNIIGSYNCLCFPGFVVTHNGD---CV 1885
Query: 1513 EINPCLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFA 1570
+ + C G + C T C C + T DGK C N CL+ G C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTA-GSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGT 1944
Query: 1571 ICNHTGQVERTCTCKPNY 1588
N G C C P +
Sbjct: 1945 CQNLEGSFR--CICPPGF 1960
Score = 66.2 bits (160), Expect = 4e-10
Identities = 73/262 (27%), Positives = 109/262 (41%), Gaps = 32/262 (12%)
Query: 1344 QCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET-CTEGKYGIHCDQACSCV 1402
+C+ P NVC +G C+D G+ +C C GF +A +T C + CD+ C
Sbjct: 1808 ECREIP----NVC-SHGDCMD-TEGSYMCLCHRGFQASADQTLCMDID---ECDRQ-PCG 1857
Query: 1403 HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN---GTCHTSANCLTNSDGTASCKCA 1459
+G C + +G +C C G+ H + D C G +CL N+ G+ C C
Sbjct: 1858 NGTC-KNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCL-NTAGSFHCLCQ 1915
Query: 1460 AGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517
GF+ +G C N C +S G C+ R C C G+ C++I+ C
Sbjct: 1916 DGFELTADGKNCVDTNEC-LSLAGTCLPGTCQNLEGSFR-CICPPGFQVQSDHCIDIDEC 1973
Query: 1518 LENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVC--TLINVCLTK--NGGCSEFAI 1571
E C CT + P C C P + + +G C T + C T+ G CS
Sbjct: 1974 SEEPNLC-LFGTCTNS-PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKA 2031
Query: 1572 CNHTGQVERTCTCKPNYIGDGF 1593
N T +T C G+G+
Sbjct: 2032 FNTT----KTRCCCSKRPGEGW 2049
Score = 65.1 bits (157), Expect = 9e-10
Identities = 99/416 (23%), Positives = 143/416 (34%), Gaps = 101/416 (24%)
Query: 659 PILPHRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARY 718
P+ C E G C++ + CPA ++ C GS +S C +
Sbjct: 1719 PLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILL-ACEDVDECGSRESPCQQN 1777
Query: 719 CNATVKIP-----KCCKGFYGPDCNQCPGG-----FSNPCSGNGQCADSLGGNGTCICEE 768
+ + IP KC +G+ C G N CS +G C D+ G+ C+C
Sbjct: 1778 ADC-INIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCS-HGDCMDT-EGSYMCLCHR 1834
Query: 769 GFQGSQCQ-FCSDPNKYGPRCNKKCLCVHGTCNNRIDSD--------------------- 806
GFQ S Q C D ++ C+++ C +GTC N I S
Sbjct: 1835 GFQASADQTLCMDIDE----CDRQP-CGNGTCKNIIGSYNCLCFPGFVVTHNGDCVDFDE 1889
Query: 807 -----------GACLTGT------CRDG----SAGRLCDKQTSACGPYVQFCHIHATCEY 845
G CL C+DG + G+ C T+ C C + TC+
Sbjct: 1890 CTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSLAGTC-LPGTCQN 1947
Query: 846 SNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TG 903
G+ CIC G++ C ++D C+ P C G+ C+C G+ +
Sbjct: 1948 LEGSFRCICPPGFQVQSDHCIDIDECSE-EPNLCLFGT--CTNSPGSFQCLCPPGFVLSD 2004
Query: 904 NGRDC-----------SEINNCLLPSAGGCHDNASCLYVGPGQ---NECE---------- 939
NG C E C +P A C PG+ + CE
Sbjct: 2005 NGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAF 2064
Query: 940 ---CKKG---FRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
C G G E + C E G C C +T G + C C GY D
Sbjct: 2065 QELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNT-DGSFRCECPFGYSLD 2118
Score = 65.1 bits (157), Expect = 9e-10
Identities = 84/323 (26%), Positives = 116/323 (35%), Gaps = 58/323 (17%)
Query: 1267 IQKNRCDNNDTTIIRGRCRTC--SSELTCPFGTKSLGNEKRRCIYT--SYFMGRRTLFIG 1322
I + C + G C S + CP G L + RC T S+ R
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFV-LSDNGHRCFDTRQSFCFTRFEAGKC 2026
Query: 1323 CQPKCVRTVITRECCAGF----FGPQCQPCP--GNA--QNVC-FGNG------------- 1360
PK T TR CC+ +G C+ CP G+A Q +C FG+G
Sbjct: 2027 SVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVN 2086
Query: 1361 -------ICLDGV----NGTGVCECGEGFS----GTACETCTEGKYGIHCDQACSCVHGR 1405
+C +GV +G+ CEC G+S G C E G C Q G
Sbjct: 2087 ECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQ------GT 2140
Query: 1406 CNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGF--Q 1463
C +G C C G+ D C+ A N++G+ C C AG+ +
Sbjct: 2141 CTN-VIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLR 2199
Query: 1464 GNGTICTAINACEISNGGCSAKA-DCKRTTPGRRVCTCKAG---YTGDGIVCLEINPCLE 1519
+G +C ++ C C A+ +CK G C C G G G C + N C
Sbjct: 2200 EDGAMCRDVDECADGQQDCHARGMECKNLI-GTFACVCPPGMRPLPGSGEGCTDDNECHA 2258
Query: 1520 NHGGCDKNAECTQTGPNQAACNC 1542
C N C T C+C
Sbjct: 2259 QPDLC-VNGRCVNTA-GSFRCDC 2279
Score = 64.7 bits (156), Expect = 1e-09
Identities = 73/292 (25%), Positives = 102/292 (34%), Gaps = 56/292 (19%)
Query: 1332 ITR-ECCAGF---FGPQCQPCP----GNAQNVC-FGNGICLDG----------------- 1365
+TR ECC G +GP+C+ CP + +C G+G +G
Sbjct: 2319 VTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGE 2378
Query: 1366 -VNGTGV--CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCN---QGPLGDGSCDCD 1419
+N G C C G++ A T + D+ CS V C + G C C
Sbjct: 2379 CINSLGSFRCHCQAGYTPDATATTC-----LDMDE-CSQVPKPCTFLCKNTKGSFLCSCP 2432
Query: 1420 VGWRGVHCDNATTED--NCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEI 1477
G+ + D T +D C H N+ G +C+C GF + C + C
Sbjct: 2433 RGYL-LEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSA 2491
Query: 1478 SNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLENHGGCDKNAECTQTGP 1535
G C A C TPG C C G+T G C ++N CD C
Sbjct: 2492 QPGPCGAHGHC-HNTPGSFRCECHQGFTLVSSGHGCEDVNE-------CDGPHRCQHGCQ 2543
Query: 1536 NQAA---CNCLPAYTGDGK--VCTLINVCLTKNGGCSEFAICNHTGQVERTC 1582
NQ C+C +T + C N C C + N G C
Sbjct: 2544 NQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVC 2595
Score = 63.5 bits (153), Expect = 2e-09
Identities = 79/293 (26%), Positives = 107/293 (36%), Gaps = 51/293 (17%)
Query: 731 GFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNK 790
GF D ++C + CS G C + + G+ C C +GF G FC D ++ +
Sbjct: 1316 GFECHDLDECVSQ-EHRCSPRGDCLN-VPGSYRCTCRQGFAGDGF-FCEDRDECAENVD- 1371
Query: 791 KCLCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGT 849
LC +G C N C G D A G F +CE G
Sbjct: 1372 --LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAF----GSCENLPGM 1425
Query: 850 ASCICKAGYEGD--GTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW----TG 903
CIC GYE D G C++++ C P C N CI T G++ C C Q + +G
Sbjct: 1426 FRCICNGGYELDRGGGNCTDINECA--DPVNCI-NGVCINT-PGSYLCSCPQDFELNPSG 1481
Query: 904 NGRDCSEINNCLLPSAGGCHDNASC---LYVGPGQNECECKKG----------------- 943
G + NC L + SC + VG + C C G
Sbjct: 1482 VGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTE 1541
Query: 944 FR-----GNGIDCEPITSCLEQTGKCHPLAS-CQS----TSSGVWSCVCQEGY 986
+R G G IT LE +C L CQ + G + C C GY
Sbjct: 1542 YRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGY 1594
Score = 63.5 bits (153), Expect = 2e-09
Identities = 79/298 (26%), Positives = 107/298 (35%), Gaps = 64/298 (21%)
Query: 1339 GFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT----ACETCTEGKYGIH 1394
GFF C N ++C NG CL+ G CEC GF T AC+ E
Sbjct: 1357 GFFCEDRDECAENV-DLC-DNGQCLNAPGGYR-CECEMGFDPTEDHRACQDVDE------ 1407
Query: 1395 CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLT----NS 1450
C Q C G C P G C C+ G+ T+ N C NC+ N+
Sbjct: 1408 CAQGNLCAFGSCENLP-GMFRCICNGGYELDRGGGNCTDIN---ECADPVNCINGVCINT 1463
Query: 1451 DGTASCKCAAGFQ----GNGTICTAINACEI-------SNGGCSA-------KADC---- 1488
G+ C C F+ G G + T C + S CSA +A C
Sbjct: 1464 PGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSL 1523
Query: 1489 -------------KRTTPGRRVCTCKAGYTGDGIVCL--EINPCLENHGGCDKNAECTQT 1533
TT R +C G+ + I + +I+ C E G C + +C T
Sbjct: 1524 GRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLC-QGGDCVNT 1582
Query: 1534 GPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI 1589
C C P Y + ++C I+ C T +G C N G TC C Y+
Sbjct: 1583 F-GSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNY--TCVCPAEYL 1637
Score = 63.2 bits (152), Expect = 3e-09
Identities = 87/347 (25%), Positives = 123/347 (35%), Gaps = 59/347 (17%)
Query: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI 90
C + L + C + + CP G+ + +G D R +F + C
Sbjct: 1973 CSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGH-RCFDTRQSFCFTRFEAGK--CSVP 2029
Query: 91 CRKDYLQPRCCPGRWGPDCIECPG-GAGSPCNGRGSCAEGMEGNGTCSCQE--GFGGTAC 147
+ + RCC C + PG G G PC C + G+ + QE FG A
Sbjct: 2030 KAFNTTKTRCC-------CSKRPGEGWGDPCE---LCPQ----EGSAAFQELCPFGHGAV 2075
Query: 148 ETCADDNLFGPSCSSVCN-CVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
D C+ C +GVC + DG CEC Y+ + + C +
Sbjct: 2076 PGPDDSREDVNECAENPGVCTNGVCVN-TDGSFRCECPFGYS--------LDFTGINCVD 2126
Query: 207 NSRCSPS--------TEDENKLECKCLPNYR-GDGKYCDPINPCLRK--ICHPHAHCTYL 255
CS T EC C + G C+ I+ C +C H T
Sbjct: 2127 TDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNT-- 2184
Query: 256 GPNRHSCTCQEGY--RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQN 313
+ CTC GY R DG +C VD C +C + CK + G C C +
Sbjct: 2185 -EGSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECK-NLIGTFACVCPPGMRP 2242
Query: 314 FVPGVGCSMTDICKSDNPCHR------NANCTTVAPGRTECICQKGY 354
+PG G + C DN CH N C A G C C +G+
Sbjct: 2243 -LPGSG----EGCTDDNECHAQPDLCVNGRCVNTA-GSFRCDCDEGF 2283
Score = 60.8 bits (146), Expect = 2e-08
Identities = 53/178 (29%), Positives = 75/178 (42%), Gaps = 19/178 (10%)
Query: 1401 CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT-CHTSANCLTNSDGTASCKCA 1459
C++GRC P C+C+VG+ D C + CH +C+ N GT C+C
Sbjct: 419 CLNGRCLPTP-SSYRCECNVGYTQDVRGECIDVDECTSSPCH-HGDCV-NIPGTYHCRCY 475
Query: 1460 AGFQGNGT--ICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEIN 1515
GFQ T C ++ C +S G C C T G C C AG+ + DG C++ N
Sbjct: 476 PGFQATPTRQACVDVDECIVSGGLCHL-GRCV-NTEGSFQCVCNAGFELSPDGKNCVDHN 533
Query: 1516 PCLENHGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTK----NGGCS 1567
C + C + G +C C P + G C I+ C T NG C+
Sbjct: 534 ECATS-TMCVNGVCLNEDG--SFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCT 588
Score = 60.1 bits (144), Expect = 3e-08
Identities = 86/356 (24%), Positives = 124/356 (34%), Gaps = 69/356 (19%)
Query: 54 CPDGYTMITSGSV---------GVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGR 104
CP GYT+ G++ G +DC + C +C ++P G
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFAC--VCPPG-MRPLPGSGE 2248
Query: 105 WGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVC 164
D EC NGR G+ C C EGF + T D GP + V
Sbjct: 2249 GCTDDNECHAQPDLCVNGR---CVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL 2305
Query: 165 NCVHGVCNSGLDGDGTCECY---SAYTGPKCDK-PIPECAAL--LCPENSRCSPSTEDEN 218
+ +S + EC GP+C+ P+P +A LCP S + D +
Sbjct: 2306 QTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVD 2365
Query: 219 K-------------------LECKCLPNYRGD--GKYCDPINPCLRKICHPHAHCTYLGP 257
+ C C Y D C ++ C ++ P CT+L
Sbjct: 2366 ECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDEC-SQVPKP---CTFLCK 2421
Query: 258 NRHS---CTCQEGY--RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC----K 308
N C+C GY DG+ C +D C NC +C + G C C
Sbjct: 2422 NTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNC---QFLC-VNTVGAFTCRCPPGFT 2477
Query: 309 EHYQNFVPGVGCSMTDICKSD-NPCHRNANCTTVAPGRTECICQKGY--VGDGLTC 361
+H+Q C D C + PC + +C PG C C +G+ V G C
Sbjct: 2478 QHHQ------ACFDNDECSAQPGPCGAHGHCHN-TPGSFRCECHQGFTLVSSGHGC 2526
Score = 59.3 bits (142), Expect = 5e-08
Identities = 52/178 (29%), Positives = 75/178 (42%), Gaps = 19/178 (10%)
Query: 732 FYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQ-GSQCQFCSDPNKYGPRCNK 790
F +C+ PG PC +G C ++ G+ C C +GF S C D N+ C+
Sbjct: 2484 FDNDECSAQPG----PCGAHGHCHNT-PGSFRCECHQGFTLVSSGHGCEDVNE----CDG 2534
Query: 791 KCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA 850
C HG N +C G + + D+ A P C A+C + G
Sbjct: 2535 PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPPT--CG-SASCRNTLGGF 2591
Query: 851 SCICKAGYEGDGTL--CSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGR 906
C+C +G++ D L C E+D C G G CS + C T G C C QG+ G+
Sbjct: 2592 RCVCPSGFDFDQALGGCQEVDECAG-RRGPCSYS--CANT-PGGFLCGCPQGYFRAGQ 2645
Score = 58.9 bits (141), Expect = 6e-08
Identities = 98/411 (23%), Positives = 137/411 (33%), Gaps = 126/411 (30%)
Query: 1837 GSELSVKCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDC---LLIDPTLGGRCDTF 1893
G EL+ K A DI + L+ C Q ++ A+ C P G D
Sbjct: 1101 GHELTAKGTACEDIDECSLSDGLCPHGQ---CVNVIGAFQCSCHAGFQSTPDRQGCVDIN 1157
Query: 1894 TTFDASGECG-SCVNTPSCPRWSKPKGVKQKCLYNLPFKR---NLEGCRERCSLVIQIPR 1949
+G C C+NT R S +G +P R +++ C E PR
Sbjct: 1158 ECRVQNGGCDVHCINTEGSYRCSCGQGYSL-----MPDGRACADVDECEEN-------PR 1205
Query: 1950 CC-KGYFGRDCQACPGGPDAPCNNRGVCLDQYSAT---------------------GECK 1987
C +G+ C PGG +R +C D + AT G+C+
Sbjct: 1206 VCDQGH----CTNMPGG------HRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCE 1255
Query: 1988 CNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDG------------ITGSGQCLCETG 2035
G C++ + R G GCSD +C+ G I GS C C G
Sbjct: 1256 NTKGSFVCHCQLGYMVRKGAT----GCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPG 1311
Query: 2036 WTGPSCDTQAVLPAVCTPP-CSAHATCKE---NNTCECNLDYEGDGITCTVVDFCKQ--- 2088
W G + + V CS C + C C + GDG C D C +
Sbjct: 1312 WVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVD 1371
Query: 2089 --DNG------------------------GCAKVARCSQKGT-----------KVSCSCQ 2111
DNG C V C+Q C C
Sbjct: 1372 LCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICN 1431
Query: 2112 KGYKGD--GHSCTEIDPCADG---LNGGCHEHATCKMTGPGKHKCECKSHY 2157
GY+ D G +CT+I+ CAD +NG C + PG + C C +
Sbjct: 1432 GGYELDRGGGNCTDINECADPVNCINGVC-------INTPGSYLCSCPQDF 1475
Score = 58.2 bits (139), Expect = 1e-07
Identities = 72/297 (24%), Positives = 103/297 (34%), Gaps = 54/297 (18%)
Query: 80 YSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQ 139
Y+ L C + D R P + DCI P G+ C C
Sbjct: 1754 YNSILLACEDV---DECGSRESPCQQNADCINIP------------------GSYRCKCT 1792
Query: 140 EGFGGTACETCADDNLFGPSCSSVCN-CVHGVCNSGLDGDGTCEC-----YSAYTGPKCD 193
G+ + C N C + N C HG C +D +G+ C + A
Sbjct: 1793 RGYKLSPGGACVGRN----ECREIPNVCSHGDC---MDTEGSYMCLCHRGFQASADQTLC 1845
Query: 194 KPIPECAALLCPENSRCSPSTEDENKLECKCLPNY----RGDGKYCDPINPCLRKICHPH 249
I EC C N C N C C P + GD D + ++C
Sbjct: 1846 MDIDECDRQPC-GNGTCKNIIGSYN---CLCFPGFVVTHNGDCVDFDECTTLVGQVCR-F 1900
Query: 250 AHCTYLGPNRHSCTCQEGYR--GDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
HC + H C CQ+G+ DG+ C+ + C G C C+ + G C C
Sbjct: 1901 GHCLNTAGSFH-CLCQDGFELTADGKNCVDTNECLSLAGTC--LPGTCQ-NLEGSFRCIC 1956
Query: 308 KEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV--GDGLTCY 362
+Q V C D C + CT +PG +C+C G+V +G C+
Sbjct: 1957 PPGFQ--VQSDHCIDIDECSEEPNLCLFGTCTN-SPGSFQCLCPPGFVLSDNGHRCF 2010
Score = 57.8 bits (138), Expect = 1e-07
Identities = 87/369 (23%), Positives = 121/369 (32%), Gaps = 70/369 (18%)
Query: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGS-VGVRDCRYTFEVRTYSLSLPGCRH 89
C + L + C + +C GYT G + V +C + +++PG H
Sbjct: 412 CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVNIPGTYH 471
Query: 90 ICRKDYLQPRCCPGRWGP-------DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGF 142
RC PG D EC G GR EG+ C C GF
Sbjct: 472 C--------RCYPGFQATPTRQACVDVDECIVSGGLCHLGR---CVNTEGSFQCVCNAGF 520
Query: 143 G-GTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYT----GPKCDKPIP 197
+ C D N C++ CV+GVC + DG +C C + G C I
Sbjct: 521 ELSPDGKNCVDHN----ECATSTMCVNGVCLNE-DGSFSCLCKPGFLLAPGGHYC-MDID 574
Query: 198 ECAALLCPENSRCSPSTEDENKLECKCLPNYR--GDGKYCDPINPCLRKICH---PHAHC 252
EC N C T E C+CL DG+ C ++ +R C+ C
Sbjct: 575 ECQTPGICVNGHC---TNTEGSFRCQCLGGLAVGTDGRVC--VDTHVRSTCYGAIEKGSC 629
Query: 253 TYLGPN---RHSCTCQEGYRGDGQVC--------------------LPVDPCQINFGNCP 289
P + C C G G+ C + D IN C
Sbjct: 630 ARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDIN--ECA 687
Query: 290 TKSTVCKY----DGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGR 345
VC + G C C Y+ G C+ D C ++ N C +PG
Sbjct: 688 LDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQN-SPGS 746
Query: 346 TECICQKGY 354
C C G+
Sbjct: 747 YSCSCPPGF 755
Score = 57.8 bits (138), Expect = 1e-07
Identities = 97/400 (24%), Positives = 135/400 (33%), Gaps = 105/400 (26%)
Query: 1855 LNGQTCRIVQRELLFDLGVAYGIDCLLIDP---TLGGR--CDTFTTFDASGEC--GSCVN 1907
L GQ CR L A CL D T G+ DT +G C G+C N
Sbjct: 1893 LVGQVCRFGHC-----LNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQN 1947
Query: 1908 TPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPG--- 1964
R P G + + + + +++ C E +L + C C PG
Sbjct: 1948 LEGSFRCICPPGFQVQSDHCI----DIDECSEEPNLCL-FGTCTNSPGSFQCLCPPGFVL 2002
Query: 1965 ---GPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGR----FGPDCLPCG---- 2013
G + C ++ A G+C FN T C R +G C C
Sbjct: 2003 SDNGHRCFDTRQSFCFTRFEA-GKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGS 2061
Query: 2014 --------------------------CSDH-GQCDDGIT----GSGQCLCETGW----TG 2038
C+++ G C +G+ GS +C C G+ TG
Sbjct: 2062 AAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTG 2121
Query: 2039 PSCDTQAVLPAVCTPPCSAHATCKENNT--------CECNLDYE-GDGITCTVVDFCKQD 2089
+C V T CS C + C C +E G +TC +D C +
Sbjct: 2122 INC--------VDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLN 2173
Query: 2090 NGGCAKVARCSQKGTKVSCSCQKGY--KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPG 2147
CA RC C+C GY + DG C ++D CADG CH
Sbjct: 2174 PLLCA--FRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADG-QQDCHARG-------- 2222
Query: 2148 KHKCECKSHYVGDGLNCEPEQLPI----DRCLQDNGQCHA 2183
ECK+ C P P+ + C DN +CHA
Sbjct: 2223 ---MECKNLIGTFACVCPPGMRPLPGSGEGCTDDN-ECHA 2258
Score = 56.2 bits (134), Expect = 4e-07
Identities = 77/274 (28%), Positives = 105/274 (38%), Gaps = 51/274 (18%)
Query: 106 GPDCI---ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSS 162
G +C+ EC AG+ G + +EG+ C C GF + C D + CS
Sbjct: 1924 GKNCVDTNECLSLAGTCLPGT---CQNLEGSFRCICPPGFQ-VQSDHCIDID----ECSE 1975
Query: 163 VCN-CVHGVCNSGLDGDGTCECYSAYT----GPKC-DKPIPECAALLCPENSRCS-PSTE 215
N C+ G C + G C C + G +C D C E +CS P
Sbjct: 1976 EPNLCLFGTCTNS-PGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRF--EAGKCSVPKAF 2032
Query: 216 DENKLECKCLPNYRGDGKYCDPINPC-------LRKICHPHAHCTYLGPNRHSCTCQEGY 268
+ K C C G+G + DP C +++C P H GP +
Sbjct: 2033 NTTKTRC-CCSKRPGEG-WGDPCELCPQEGSAAFQELC-PFGHGAVPGP--------DDS 2081
Query: 269 RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS 328
R D V+ C N G C + VC + G CEC Y G+ C TD C
Sbjct: 2082 RED------VNECAENPGVCT--NGVC-VNTDGSFRCECPFGYSLDFTGINCVDTDECSV 2132
Query: 329 DNPCHRNANCTTVAPGRTECICQKGY-VGDGLTC 361
+PC + CT V G EC C G+ G +TC
Sbjct: 2133 GHPCGQ-GTCTNVI-GGFECACADGFEPGLMMTC 2164
Score = 56.2 bits (134), Expect = 4e-07
Identities = 61/205 (29%), Positives = 76/205 (37%), Gaps = 44/205 (21%)
Query: 1323 CQPKCVRTVITREC-CAGFFGPQCQPCPGNAQ-----NVCFGNGICLDGVNGTGVCECGE 1376
CQ CV TV C C F Q C N + C +G C G+ CEC +
Sbjct: 2457 CQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHC-HNTPGSFRCECHQ 2515
Query: 1377 GF----SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGW-RGVHCDNAT 1431
GF SG CE E CD C HG NQ LG C C G+ +
Sbjct: 2516 GFTLVSSGHGCEDVNE------CDGPHRCQHGCQNQ--LGGYRCSCPQGFTQHSQWAQCV 2567
Query: 1432 TEDNCNGTCHT--SANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCK 1489
E+ C + T SA+C N+ G C C +GF + + GGC +C
Sbjct: 2568 DENECALSPPTCGSASC-RNTLGGFRCVCPSGFDFDQAL-----------GGCQEVDECA 2615
Query: 1490 ----------RTTPGRRVCTCKAGY 1504
TPG +C C GY
Sbjct: 2616 GRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 55.8 bits (133), Expect = 5e-07
Identities = 61/210 (29%), Positives = 81/210 (38%), Gaps = 25/210 (11%)
Query: 793 LCVHGTCNNRIDSDGA-CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS 851
LC++G C S C G +D G D P CH H C GT
Sbjct: 418 LCLNGRCLPTPSSYRCECNVGYTQD-VRGECIDVDECTSSP----CH-HGDCVNIPGTYH 471
Query: 852 CICKAGYEGDGT--LCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGNGRD 907
C C G++ T C ++D C + GG C+ T G+ CVC G+ + +G++
Sbjct: 472 CRCYPGFQATPTRQACVDVDEC--IVSGGLCHLGRCVNT-EGSFQCVCNAGFELSPDGKN 528
Query: 908 CSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLEQTGKCH 965
C + N C + N CL G C CK GF G C I C QT
Sbjct: 529 CVDHNEC---ATSTMCVNGVCLN-EDGSFSCLCKPGFLLAPGGHYCMDIDEC--QTPGIC 582
Query: 966 PLASCQSTSSGVWSCVCQEGYE--GDGFLC 993
C +T G + C C G DG +C
Sbjct: 583 VNGHCTNT-EGSFRCQCLGGLAVGTDGRVC 611
Score = 55.5 bits (132), Expect = 7e-07
Identities = 84/369 (22%), Positives = 123/369 (33%), Gaps = 84/369 (22%)
Query: 673 KLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGF 732
+ G C++ + + C E TA CV + SL C +P C+
Sbjct: 1899 RFGHCLNTAGSFHCLCQDGFELTA-DGKNCVDTNECLSLAGTC---------LPGTCQNL 1948
Query: 733 YGPDCNQCPGGF---SNPCSGNGQCADSLG-----------GNGTCICEEGF----QGSQ 774
G CP GF S+ C +C++ G+ C+C GF G +
Sbjct: 1949 EGSFRCICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHR 2008
Query: 775 C----------QF----CSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTC-RDGSA 819
C +F CS P + + C C+ R C ++GSA
Sbjct: 2009 CFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCC------CSKRPGEGWGDPCELCPQEGSA 2062
Query: 820 G--RLCD-------------KQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGD--G 862
LC + + C C + C ++G+ C C GY D G
Sbjct: 2063 AFQELCPFGHGAVPGPDDSREDVNECAENPGVC-TNGVCVNTDGSFRCECPFGYSLDFTG 2121
Query: 863 TLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT-GNGRDCSEINNCLLPS--- 918
C + D C+ P G I G C C G+ G C +I+ C L
Sbjct: 2122 INCVDTDECSVGHPCGQGTCTNVI----GGFECACADGFEPGLMMTCEDIDECSLNPLLC 2177
Query: 919 AGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLEQTGKCHPLASCQSTSSG 976
A CH+ G C C G+ R +G C + C + CH G
Sbjct: 2178 AFRCHNTE-------GSYLCTCPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIG 2230
Query: 977 VWSCVCQEG 985
++CVC G
Sbjct: 2231 TFACVCPPG 2239
Score = 55.1 bits (131), Expect = 9e-07
Identities = 71/289 (24%), Positives = 107/289 (37%), Gaps = 60/289 (20%)
Query: 736 DCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQC-QFCSDPNKYGPRCNKKCLC 794
D ++C S+PC +G C + + G C C GFQ + Q C D ++ C+
Sbjct: 449 DVDECT---SSPCH-HGDCVN-IPGTYHCRCYPGFQATPTRQACVDVDE--------CIV 495
Query: 795 VHGTCN--NRIDSDGA----CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNG 848
G C+ ++++G+ C G D A ++ C +G
Sbjct: 496 SGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMC----VNGVCLNEDG 551
Query: 849 TASCICKAGY--EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT--GN 904
+ SC+CK G+ G C ++D C TPG C N C T G+ C C G +
Sbjct: 552 SFSCLCKPGFLLAPGGHYCMDIDECQ--TPGICV-NGHCTNT-EGSFRCQCLGGLAVGTD 607
Query: 905 GRDCSEINNCLLPSAGGCHDNASCLYVGPG---QNECECKKGFRGNGIDCE--PITSCLE 959
GR C ++ + + G + SC PG ++EC C G G C+ P E
Sbjct: 608 GRVC--VDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAE 665
Query: 960 QTGKC----------HPLASCQ-----------STSSGVWSCVCQEGYE 987
C + C G + CVC GYE
Sbjct: 666 FQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYE 714
Score = 54.7 bits (130), Expect = 1e-06
Identities = 71/281 (25%), Positives = 99/281 (35%), Gaps = 47/281 (16%)
Query: 1326 KCVRTVITRECC--AGF-FGPQCQPCPGNAQNVCFGNGICLDGV----NGTGVCECGEGF 1378
+CV T + +C AGF P + C + N C + +C++GV +G+ C C GF
Sbjct: 504 RCVNTEGSFQCVCNAGFELSPDGKNCVDH--NECATSTMCVNGVCLNEDGSFSCLCKPGF 561
Query: 1379 ----SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDC----DVGWRGVHCDNA 1430
G C E C CV+G C G C C VG G C +
Sbjct: 562 LLAPGGHYCMDIDE------CQTPGICVNGHCTNTE-GSFRCQCLGGLAVGTDGRVCVDT 614
Query: 1431 TTEDNCNGTCHTSANCLTNSDGTAS---CKCAAGFQGNGTICTAINACEISNGGCSAKAD 1487
C G +C GT + C CA G G C C AK
Sbjct: 615 HVRSTCYGAIE-KGSCARPFPGTVTKSECCCANPDHGFGEPCQL----------CPAKDS 663
Query: 1488 CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYT 1547
+ + +C+ G T DG +IN C + C G + CN
Sbjct: 664 AEF----QALCSSGLGITTDG---RDINECALDPEVCANGVCENLRGSYRCVCNLGYEAG 716
Query: 1548 GDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNY 1588
GK CT ++ C + C N G +C+C P +
Sbjct: 717 ASGKDCTDVDECALNSLLCDNGWCQNSPGSY--SCSCPPGF 755
Score = 53.9 bits (128), Expect = 2e-06
Identities = 105/430 (24%), Positives = 147/430 (34%), Gaps = 80/430 (18%)
Query: 1887 GGRC-----DTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERC 1941
GGRC +T + G C P P+G + F++ C +R
Sbjct: 301 GGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCPPRGSNE-------FQQL---CAQRL 350
Query: 1942 SLVIQIPRCCKGY--FGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTG---FNGTA 1996
L+ P G FG + P GP A N G + G N G N T
Sbjct: 351 PLLPGHPGLFPGLLGFGSNGMGPPLGP-ARLNPHGSDARGIPSLGPGNSNIGTATLNQTI 409
Query: 1997 ------CEMCWPGRFGPDCLPCGCSDHGQCDDGITGS--GQCLCETGWTGPSCDTQAVLP 2048
+C GR CLP S +C+ G T G+C+ T C +
Sbjct: 410 DICRHFTNLCLNGR----CLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHGDCVN 465
Query: 2049 AVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC 2108
T C + + T + C VD C +GG + RC C
Sbjct: 466 IPGTYHCRCYPGFQATPTRQA----------CVDVDECIV-SGGLCHLGRCVNTEGSFQC 514
Query: 2109 SCQKGYK--GDGHSCTEIDPCADG---LNGGCHEHATCKMTGPGKHKCECK--------S 2155
C G++ DG +C + + CA +NG C + G C CK
Sbjct: 515 VCNAGFELSPDGKNCVDHNECATSTMCVNGVC-------LNEDGSFSCLCKPGFLLAPGG 567
Query: 2156 HYVGDGLNCEPEQLPID-RCLQDNG----QC------HADAK-CVDLHFQDTTVGVFHLR 2203
HY D C+ + ++ C G QC D + CVD H + T G
Sbjct: 568 HYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKG 627
Query: 2204 SPLGQYKLTFDKAREACANEAATMATYNQLSYAQ-KAKYH-LCSAGWLET--GRVAYPTA 2259
S + T K+ CAN QL A+ A++ LCS+G T GR A
Sbjct: 628 SCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTDGRDINECA 687
Query: 2260 FASQNCGSGV 2269
+ C +GV
Sbjct: 688 LDPEVCANGV 697
Score = 53.5 bits (127), Expect = 3e-06
Identities = 66/282 (23%), Positives = 100/282 (35%), Gaps = 37/282 (13%)
Query: 1889 RCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIP 1948
RC+ F+ + +C + C P C+ N+ G RC
Sbjct: 1745 RCECPAGFNYNSILLACEDVDECGSRESPCQQNADCI-------NIPGSY-RC------- 1789
Query: 1949 RCCKGYFGRDCQACPGGPDAP-----CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPG 2003
+C +GY AC G + C++ G C+D + C C+ GF +A +
Sbjct: 1790 KCTRGYKLSPGGACVGRNECREIPNVCSH-GDCMDT-EGSYMCLCHRGFQASADQTLCMD 1847
Query: 2004 RFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWT----GPSCDTQ---AVLPAVCTPPCS 2056
D PCG +G C + I GS CLC G+ G D ++ VC
Sbjct: 1848 IDECDRQPCG---NGTCKN-IIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHC 1903
Query: 2057 AHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG 2116
+ + C+ + DG C + C G C C C C G++
Sbjct: 1904 LNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQV 1962
Query: 2117 DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYV 2158
C +ID C++ N TC PG +C C +V
Sbjct: 1963 QSDHCIDIDECSEEPN--LCLFGTC-TNSPGSFQCLCPPGFV 2001
Score = 52.8 bits (125), Expect = 4e-06
Identities = 68/272 (25%), Positives = 90/272 (33%), Gaps = 34/272 (12%)
Query: 1337 CAGFFGPQCQPCPGNAQNVCFGNG-------ICLDGVNGTGVCECGEGFSGTACETCTEG 1389
C G CP V GN +C NGT C+ F+ T C
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT--CQNELAFNVTRKMCCCSY 1678
Query: 1390 KYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRG----VHCDNATTEDNCNGTCHTSAN 1445
G ++ C C D C G +H D C AN
Sbjct: 1679 NIGQAWNRPCEA----CPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICAN 1734
Query: 1446 CLT-NSDGTASCKCAAGFQGNGTI--CTAINACEISNGGCSAKADCKRTTPGRRVCTCKA 1502
+ N G+ C+C AGF N + C ++ C C ADC PG C C
Sbjct: 1735 GICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADC-INIPGSYRCKCTR 1793
Query: 1503 GY-TGDGIVCLEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLINVCL 1560
GY G C+ N C E C + +C T G C+ + D +C I+ C
Sbjct: 1794 GYKLSPGGACVGRNECREIPNVC-SHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECD 1852
Query: 1561 TK---NGGCSEFAICNHTGQVERTCTCKPNYI 1589
+ NG C N G C C P ++
Sbjct: 1853 RQPCGNGTCK-----NIIGSY--NCLCFPGFV 1877
Score = 52.4 bits (124), Expect = 6e-06
Identities = 76/312 (24%), Positives = 100/312 (32%), Gaps = 60/312 (19%)
Query: 1903 GSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQI--PRCCKGYFGRDCQ 1960
G CVNT + P G Y+L + + CS I P C G
Sbjct: 1577 GDCVNTFGSFQCECPPG------YHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTC 1630
Query: 1961 ACP-------GGPDAPCNNRGVCLDQYSATGECKCNTGFNGTA----------------C 1997
CP GG + + VC Y+ T C+ FN T C
Sbjct: 1631 VCPAEYLQVNGGNNCMDMRKSVCFRHYNGT--CQNELAFNVTRKMCCCSYNIGQAWNRPC 1688
Query: 1998 EMCWPGRFGPDC-LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCS 2056
E C P PD + CG G D TG + E G +PA+C
Sbjct: 1689 EAC-PTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECG----------EIPAICANGIC 1737
Query: 2057 AHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK- 2115
+ C +Y + C VD C C + A C C C +GYK
Sbjct: 1738 INQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL 1797
Query: 2116 GDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQ---LPID 2172
G +C + C + N H C M G + C C G +Q + ID
Sbjct: 1798 SPGGACVGRNECREIPN--VCSHGDC-MDTEGSYMCLCHR-----GFQASADQTLCMDID 1849
Query: 2173 RCLQD---NGQC 2181
C + NG C
Sbjct: 1850 ECDRQPCGNGTC 1861
Score = 52.0 bits (123), Expect = 7e-06
Identities = 98/419 (23%), Positives = 138/419 (32%), Gaps = 103/419 (24%)
Query: 31 CDRKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRD---CR---YTFEVRTYSLSL 84
CD + + +C + + C GY M+ G+ G D C + + L++
Sbjct: 1242 CDLNPHICLHGDCENTKGSFVCHCQLGY-MVRKGATGCSDVDECEVGGHNCDSHASCLNI 1300
Query: 85 PG----------------CRHICRKDYLQPRCCPGRWGPDCIECPG-----------GAG 117
PG C + + RC P DC+ PG G G
Sbjct: 1301 PGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRG---DCLNVPGSYRCTCRQGFAGDG 1357
Query: 118 SPCNGRGSCAEGME-----------GNGTCSCQEGFGGT----AC---ETCADDNL--FG 157
C R CAE ++ G C C+ GF T AC + CA NL FG
Sbjct: 1358 FFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFG 1417
Query: 158 PSCSSVCNCVHGVCNSGLD---GDGTCECYSAYTGP-KCDKPI----PECAALLCPENSR 209
SC ++ +CN G + G G C + P C + P CP++
Sbjct: 1418 -SCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPGSYLCSCPQDFE 1476
Query: 210 CSPS---TEDENKLECKCLPNYRGD-GKYCDPI-------------------NPCLRKIC 246
+PS D C + RGD G C NPC ++C
Sbjct: 1477 LNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPC--ELC 1534
Query: 247 HPHAHCTYLGPNRHSCTCQEGYRGDGQVCL--PVDPCQINFGNCPTKSTVCKYDGPGQSH 304
P A+ T R C EG++ + + +D CQ G C V + G
Sbjct: 1535 -PMANTT---EYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTF---GSFQ 1587
Query: 305 CECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY--VGDGLTC 361
CEC Y C D C + + C G C+C Y V G C
Sbjct: 1588 CECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTL-GNYTCVCPAEYLQVNGGNNC 1645
Score = 49.3 bits (116), Expect = 5e-05
Identities = 80/335 (23%), Positives = 116/335 (34%), Gaps = 62/335 (18%)
Query: 1878 DCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSC---------PRWSKPKGVKQKCLYNL 1928
DC+ I T RC + F A+ +CV+ C R +G Q C+ N
Sbjct: 462 DCVNIPGTYHCRC--YPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQ-CVCNA 518
Query: 1929 PFKRNLEG--C---RERCSLVIQIPRCCKGYFGR-DCQACPGGPDAP----------CNN 1972
F+ + +G C E + + + C G C PG AP C
Sbjct: 519 GFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQT 578
Query: 1973 RGVCLDQYSATGE----CKCNTGFN-GTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGS 2027
G+C++ + E C+C G GT +C C G + G C G+
Sbjct: 579 PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCY--GAIEKGSCARPFPGT 636
Query: 2028 ---GQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVD 2084
+C C G Q C A + + C L DG ++
Sbjct: 637 VTKSECCCANPDHGFGEPCQL---------CPAKDSAEFQALCSSGLGITTDGRD---IN 684
Query: 2085 FCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG--DGHSCTEIDPCADGLNGGCHEHATCK 2142
C D CA C C C GY+ G CT++D CA LN ++ C+
Sbjct: 685 ECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASGKDCTDVDECA--LNSLLCDNGWCQ 741
Query: 2143 MTGPGKHKCECKS--HYVGDGLNCEPEQLPIDRCL 2175
PG + C C H+ D C+ +D CL
Sbjct: 742 -NSPGSYSCSCPPGFHFWQDTEICK----DVDECL 771
Score = 48.9 bits (115), Expect = 6e-05
Identities = 80/309 (25%), Positives = 101/309 (32%), Gaps = 96/309 (31%)
Query: 98 PRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGG--TACETCADDNL 155
P C R+ C CPG P GR C + +C EGF C TCAD L
Sbjct: 57 PNVCGSRFHAYC--CPGWRTFP--GRSQCVVPICRR---ACGEGFCSQPNLC-TCADGTL 108
Query: 156 FGPSC--SSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPS 213
PSC S C N G +C C YTG C +PI + C RC
Sbjct: 109 -APSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRG---CHNGGRCI-- 162
Query: 214 TEDENKLEC-------KCLPNYRGDGKYCDPINP-----------CLRKIC--------- 246
N+ C +C +YR G + P C + +C
Sbjct: 163 --GPNRCACVYGFMGPQCERDYR-TGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWG 219
Query: 247 --------HPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYD 298
PH PN H+ CQ+ VD CQ G C S V +
Sbjct: 220 LPCELCPAQPHPCRRGFIPNIHTGACQD-----------VDECQAVPGLCQGGSCV---N 265
Query: 299 GPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPC--HRNANCTTVAPG------------ 344
G HC C VG ++D S C +R C +V G
Sbjct: 266 MVGSFHCRCP---------VGHRLSD---SSAACEDYRAGACFSVLFGGRCAGDLAGHYT 313
Query: 345 RTECICQKG 353
R +C C +G
Sbjct: 314 RRQCCCDRG 322
Score = 48.1 bits (113), Expect = 1e-04
Identities = 65/269 (24%), Positives = 92/269 (34%), Gaps = 42/269 (15%)
Query: 1944 VIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPG 2003
++Q P C F C CPG P ++ V A GE C+ C C G
Sbjct: 53 ILQGPNVCGSRFHAYC--CPGWRTFPGRSQCVVPICRRACGEGFCS---QPNLCT-CADG 106
Query: 2004 RFGPDC---LPCGCSDHGQCDDGITGSG-QCLCETGWTGPSCDTQAVLPAVCTPPCSAHA 2059
P C GCS C +G T G CLC+ G+TG C +C C
Sbjct: 107 TLAPSCGVSRGSGCSV--SCMNGGTCRGASCLCQKGYTGTVCG-----QPICDRGCHNGG 159
Query: 2060 TCKENNTC---------ECNLDYE-GDGITCTVVDFCKQDNGG--CAKVARCSQKGTK-- 2105
C N C +C DY G + C+ G C K C+ G
Sbjct: 160 RCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWG 219
Query: 2106 VSCS--------CQKGYKGDGH--SCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKS 2155
+ C C++G+ + H +C ++D C + G C + M G +C
Sbjct: 220 LPCELCPAQPHPCRRGFIPNIHTGACQDVDEC-QAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Query: 2156 HYVGDGLNCEPEQLPIDRCLQDNGQCHAD 2184
CE + + G+C D
Sbjct: 279 RLSDSSAACEDYRAGACFSVLFGGRCAGD 307
Score = 48.1 bits (113), Expect = 1e-04
Identities = 61/262 (23%), Positives = 84/262 (32%), Gaps = 55/262 (20%)
Query: 1370 GVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDN 1429
G C + F+ T C + G C C Q C G V +
Sbjct: 2024 GKCSVPKAFNTTKTRCCCSKRPGEGWGDPCEL----CPQEGSAAFQELCPFGHGAVPGPD 2079
Query: 1430 ATTED--NCN---GTCHTSANCLTNSDGTASCKCAAGFQ--------------------G 1464
+ ED C G C T+ C+ N+DG+ C+C G+ G
Sbjct: 2080 DSREDVNECAENPGVC-TNGVCV-NTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCG 2137
Query: 1465 NGTICTAINA--CEISNG-------GCSAKADCK----------RTTPGRRVCTCKAGYT 1505
GT I C ++G C +C T G +CTC AGYT
Sbjct: 2138 QGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYT 2197
Query: 1506 --GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPA---YTGDGKVCTLINVCL 1560
DG +C +++ C + C + AC C P G G+ CT N C
Sbjct: 2198 LREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECH 2257
Query: 1561 TKNGGCSEFAICNHTGQVERTC 1582
+ C N G C
Sbjct: 2258 AQPDLCVNGRCVNTAGSFRCDC 2279
Score = 47.8 bits (112), Expect = 1e-04
Identities = 83/394 (21%), Positives = 129/394 (32%), Gaps = 114/394 (28%)
Query: 53 KCPDGYTMITSGSVGVRDCRYTFEVRTYS-LSLPGCRH--------ICRKDYLQPRCCPG 103
+CP GY + S R C E T+S + PG + +C +YLQ
Sbjct: 1589 ECPPGYHL----SEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVN---- 1640
Query: 104 RWGPDCIECPGGAGSPC--NGRGSCAEGMEGNGT---CSCQEGFG---GTACETCADDNL 155
G +C++ S C + G+C + N T C C G CE C
Sbjct: 1641 -GGNNCMDM---RKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTP-- 1694
Query: 156 FGPSCSSVCN---------------------------CVHGVCNSGLDGDGTCECYSAYT 188
P +C C +G+C + + G CEC + +
Sbjct: 1695 ISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQI-GSFRCECPAGFN 1753
Query: 189 GPK----CDKPIPECAALL--CPENSRCSPSTEDENKLECKCLPNYR-GDGKYCDPINPC 241
C+ + EC + C +N+ C CKC Y+ G C N C
Sbjct: 1754 YNSILLACED-VDECGSRESPCQQNADC---INIPGSYRCKCTRGYKLSPGGACVGRNEC 1809
Query: 242 --LRKICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCLPVDPCQ--------------- 282
+ +C H C + C C G++ D +C+ +D C
Sbjct: 1810 REIPNVCS-HGDCMDT-EGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGS 1867
Query: 283 -----------------INFGNCPTK-STVCKY----DGPGQSHCECKEHYQNFVPGVGC 320
++F C T VC++ + G HC C++ ++ G C
Sbjct: 1868 YNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Query: 321 SMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
T+ C S C + G CIC G+
Sbjct: 1928 VDTNECLSLAGTCLPGTCQNL-EGSFRCICPPGF 1960
Score = 47.0 bits (110), Expect = 2e-04
Identities = 64/271 (23%), Positives = 89/271 (32%), Gaps = 61/271 (22%)
Query: 1958 DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGT-ACEMCWPGRFGP---DCLPCG 2013
D C PD N R V + + C C+ GF + C R GP + L
Sbjct: 2252 DDNECHAQPDLCVNGRCV---NTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTM 2308
Query: 2014 CSDHGQCDDGITGSGQCLCE--TGWTGPSC----------------------------DT 2043
C + +T + +C C GW GP C D
Sbjct: 2309 CRSLSSSSEAVTRA-ECCCGGGRGW-GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDE 2366
Query: 2044 QAVLPAVCTPPCSAHATCKENN---TCECNLDYEGDGI--TCTVVDFCKQDNGGCAKVAR 2098
+L +C AH C + C C Y D TC +D C Q C + +
Sbjct: 2367 CRMLAHLC-----AHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCK 2421
Query: 2099 CSQKGTKVSCSCQKGY--KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSH 2156
+ KG+ + CSC +GY + DG +C ++D C H + G C C
Sbjct: 2422 -NTKGSFL-CSCPRGYLLEEDGRTCKDLDECTSRQ----HNCQFLCVNTVGAFTCRCPPG 2475
Query: 2157 YVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
+ C D C G C A C
Sbjct: 2476 FTQHHQAC----FDNDECSAQPGPCGAHGHC 2502
Score = 44.3 bits (103), Expect = 0.002
Identities = 62/289 (21%), Positives = 87/289 (30%), Gaps = 61/289 (21%)
Query: 1962 CPGGPDAPCNNRGV----CLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDH 2017
CP G R V L A GEC + G C+ + PD C D
Sbjct: 2351 CPHGSGYTAEGRDVDECRMLAHLCAHGECINSLGSFRCHCQ----AGYTPDATATTCLDM 2406
Query: 2018 GQCDD----------GITGSGQCLCETGWT----GPSC-------DTQAVLPAVCTPPCS 2056
+C GS C C G+ G +C Q +C
Sbjct: 2407 DECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVG 2466
Query: 2057 AHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK- 2115
A TC C + C D C G C C C C +G+
Sbjct: 2467 AF-------TCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTL 2519
Query: 2116 -GDGHSCTEIDPCADG---LNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPI 2171
GH C +++ C DG GC G ++C C + +
Sbjct: 2520 VSSGHGCEDVNEC-DGPHRCQHGCQNQL-------GGYRCSCPQGFT--------QHSQW 2563
Query: 2172 DRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREAC 2220
+C+ +N + C ++ T+G F P G FD+A C
Sbjct: 2564 AQCVDENECALSPPTCGSASCRN-TLGGFRCVCPSG---FDFDQALGGC 2608
Score = 43.9 bits (102), Expect = 0.002
Identities = 49/198 (24%), Positives = 68/198 (34%), Gaps = 50/198 (25%)
Query: 207 NSRCSPSTEDENKLECKCLPNYRGDGK-YCDPINPCLRKICHPHAHCTYLGPNRHSCTCQ 265
N RC P+ + C+C Y D + C ++ C CH H C + P + C C
Sbjct: 421 NGRCLPTP---SSYRCECNVGYTQDVRGECIDVDECTSSPCH-HGDCVNI-PGTYHCRCY 475
Query: 266 EGYRGDG--QVCLPVDPCQINFGNCP---------------------------------- 289
G++ Q C+ VD C ++ G C
Sbjct: 476 PGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 290 TKSTVCK----YDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGR 345
ST+C + G C CK + G C D C++ C N +CT G
Sbjct: 536 ATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGIC-VNGHCTN-TEGS 593
Query: 346 TECICQKGY-VG-DGLTC 361
C C G VG DG C
Sbjct: 594 FRCQCLGGLAVGTDGRVC 611
Score = 43.9 bits (102), Expect = 0.002
Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 59/199 (29%)
Query: 1958 DCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGF----NGTACE---MCWPGRFGPDCL 2010
+C A PG PC G C + + C+C+ GF +G CE C GP
Sbjct: 2488 ECSAQPG----PCGAHGHCHNT-PGSFRCECHQGFTLVSSGHGCEDVNEC----DGPHRC 2538
Query: 2011 PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC--TPPCSAHATCKENN--- 2065
GC + G +C C G+T S Q V C +PP A+C+
Sbjct: 2539 QHGCQNQ-------LGGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGF 2591
Query: 2066 TCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVS-----------CSCQKGY 2114
C C ++ D Q GGC +V C+ + S C C +GY
Sbjct: 2592 RCVCPSGFDFD-----------QALGGCQEVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Query: 2115 --KGDGHSCTEIDPCADGL 2131
G GH C GL
Sbjct: 2641 FRAGQGH-------CVSGL 2652
Score = 41.2 bits (95), Expect = 0.013
Identities = 47/210 (22%), Positives = 66/210 (31%), Gaps = 43/210 (20%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
C G P C G+ +V NG G + C C +G++GT C C
Sbjct: 103 CADGTLAPSCGVSRGSGCSVSCMNGGTCRGAS----CLCQKGYTGTVCGQPI-------C 151
Query: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455
D+ C GRC +G C C G+ G C+ C G G
Sbjct: 152 DRGCH-NGGRC----IGPNRCACVYGFMGPQCERDYRTGPCFGQV-----------GPEG 195
Query: 1456 CKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGY-----TGDGIV 1510
C+ Q G +CT C + P C+ G+ TG
Sbjct: 196 CQ----HQLTGLVCTKALCCATVGRAWGLPCELCPAQPH----PCRRGFIPNIHTG---A 244
Query: 1511 CLEINPCLENHGGCDKNAECTQTGPNQAAC 1540
C +++ C G C + G C
Sbjct: 245 CQDVDECQAVPGLCQGGSCVNMVGSFHCRC 274
Score = 40.8 bits (94), Expect = 0.017
Identities = 34/138 (24%), Positives = 47/138 (34%), Gaps = 15/138 (10%)
Query: 1464 GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI-VCLEINPCLEN-- 1520
G T+ I+ C C C TP C C GYT D C++++ C +
Sbjct: 401 GTATLNQTIDICRHFTNLC-LNGRCL-PTPSSYRCECNVGYTQDVRGECIDVDECTSSPC 458
Query: 1521 -HGGCDKNAECTQTGPNQAACNCLPAY--TGDGKVCTLINVCLTKNGGCSEFAICNHTGQ 1577
HG C P C C P + T + C ++ C+ G C N G
Sbjct: 459 HHGDCVNI-------PGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVNTEGS 511
Query: 1578 VERTCTCKPNYIGDGFTC 1595
+ C DG C
Sbjct: 512 FQCVCNAGFELSPDGKNC 529
Score = 40.0 bits (92), Expect = 0.029
Identities = 70/284 (24%), Positives = 91/284 (32%), Gaps = 85/284 (29%)
Query: 726 PKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
P C + C CPG + P G QC + C EGF CS PN
Sbjct: 57 PNVCGSRFHAYC--CPGWRTFP--GRSQCVVPICRRA---CGEGF-------CSQPN--- 99
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCD-KQTSACGPYVQFCHIHATCE 844
LC TC DG+ C + S C C TC
Sbjct: 100 -------LC------------------TCADGTLAPSCGVSRGSGCSVS---CMNGGTCR 131
Query: 845 YSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGN 904
ASC+C+ GY GT+C + + GC CI G + C C G+ G
Sbjct: 132 ----GASCLCQKGY--TGTVCGQ-----PICDRGCHNGGRCI----GPNRCACVYGFMGP 176
Query: 905 GRDCSEINNCLLPSAG--GCHDNAS---------CLYVGPGQN-ECE--------CKKGF 944
+ G GC + C VG CE C++GF
Sbjct: 177 QCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQPHPCRRGF 236
Query: 945 RGN--GIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
N C+ + C G C SC + G + C C G+
Sbjct: 237 IPNIHTGACQDVDECQAVPGLCQG-GSCVN-MVGSFHCRCPVGH 278
Score = 33.9 bits (76), Expect = 2.1
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 713 SGCARYC--NATVKIPKCC--KGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCIC 766
SGC+ C T + C KG+ G C Q C G C G+C G C C
Sbjct: 118 SGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRG----CHNGGRCI----GPNRCAC 169
Query: 767 EEGFQGSQCQ 776
GF G QC+
Sbjct: 170 VYGFMGPQCE 179
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 104 bits (259), Expect = 1e-21
Identities = 94/357 (26%), Positives = 129/357 (36%), Gaps = 64/357 (17%)
Query: 53 KCPDGYTMITSGSVGVRDCR----YTFEVRTYSLSLP----------GCRHICRKDYLQP 98
+C +G T + +G CR +T E YS S P G H+ +D +
Sbjct: 72 RCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYEC 131
Query: 99 RCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
C G G +C PC GS + +C C GF G CET ++
Sbjct: 132 TCQVGFTGKECQWTDACLSHPC-ANGSTCTTVANQFSCKCLTGFTGQKCETDVNE----- 185
Query: 159 SCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
C +C HG L G C+C +TG CD CA C C + +
Sbjct: 186 -CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQT--GDF 242
Query: 219 KLECKCLPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCL- 276
EC CLP + +G C+ I+ C C C G N ++C C + GQ C
Sbjct: 243 TFECNCLPGF--EGSTCERNIDDCPNHRCQNGGVCVD-GVNTYNCRCPPQW--TGQFCTE 297
Query: 277 PVDPCQINFGNCPTKSTVCKYDG-------PGQSHCECKEHYQNFV-------------- 315
VD C + C T +G G S +C E+ +
Sbjct: 298 DVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 316 -----------PGVGCSMTDICKSDNPCHRNANC-TTVAPGRTECICQKGYVGDGLT 360
G+ C + D C S NPCH+ A C T G+ C C +GY G T
Sbjct: 358 ASFSCMCPEGKAGLLCHLDDACIS-NPCHKGALCDTNPLNGQYICTCPQGYKGADCT 413
Score = 101 bits (251), Expect = 1e-20
Identities = 98/358 (27%), Positives = 134/358 (37%), Gaps = 47/358 (13%)
Query: 12 GLVVQNFCSPAETTGQARRCDRKSLLTIRTECRS---CALNLGVKCPDGYTMITSGSVGV 68
G+ N P + TGQ D L C++ CA G GY +
Sbjct: 278 GVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNG-----GYGCVCVNGWSG 332
Query: 69 RDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSC-A 127
DC + ++ PG I R C G+ G C +PC+ C
Sbjct: 333 DDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDT 392
Query: 128 EGMEGNGTCSCQEGFGGTACETCADDNLFGPS--CSSVCNCVHGVCNSGLDGDGTCECYS 185
+ G C+C +G+ G C D+ S C CV+ DG CEC
Sbjct: 393 NPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVN------TDGAFHCECLK 446
Query: 186 AYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINPCLRK 244
Y GP+C+ I EC + C ++ C + C C+P ++ G +C+ IN C
Sbjct: 447 GYAGPRCEMDINECHSDPCQNDATC---LDKIGGFTCLCMPGFK--GVHCELEINECQSN 501
Query: 245 ICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCK-----YDG 299
C + C NR C C G+ G PV CQI+ +C ST C D
Sbjct: 502 PCVNNGQCVD-KVNRFQCLCPPGFTG------PV--CQIDIDDC--SSTPCLNGAKCIDH 550
Query: 300 PGQSHCECKEHYQNFVPGVGCSMT-DICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
P C+C + GV C D C D PCH + C T CIC GY+G
Sbjct: 551 PNGYECQCATGF----TGVLCEENIDNCDPD-PCH-HGQCQDGIDSYT-CICNPGYMG 601
Score = 100 bits (250), Expect = 1e-20
Identities = 81/262 (30%), Positives = 103/262 (39%), Gaps = 27/262 (10%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICL-DGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
+C GF G CQ +N C G C+ + G C C GF+G C+ T
Sbjct: 52 KCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHP--- 108
Query: 1394 HCDQACSCVH-GRCNQGPLGDGSCDCDVGWRGVHC---DNATTEDNCNG-TCHTSANCLT 1448
C + C++ G C+ C C VG+ G C D + NG TC T AN
Sbjct: 109 -CFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN--- 164
Query: 1449 NSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDG 1508
SCKC GF G T +N C+I G C C PG C C G+TG
Sbjct: 165 ----QFSCKCLTGFTGQ-KCETDVNECDIP-GHCQHGGTC-LNLPGSYQCQCPQGFTGQY 217
Query: 1509 IVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSE 1568
L + PC + C C QTG CNCLP + +G C N+ N C
Sbjct: 218 CDSLYV-PCAPS--PCVNGGTCRQTGDFTFECNCLPGF--EGSTCER-NIDDCPNHRCQN 271
Query: 1569 FAICNHTGQVERTCTCKPNYIG 1590
+C G C C P + G
Sbjct: 272 GGVC-VDGVNTYNCRCPPQWTG 292
Score = 100 bits (250), Expect = 1e-20
Identities = 92/297 (30%), Positives = 125/297 (42%), Gaps = 66/297 (22%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQF----C 778
+C KG+ GP C N+C S+PC + C D +GG TC+C GF+G C+ C
Sbjct: 443 ECLKGYAGPRCEMDINEC---HSDPCQNDATCLDKIGGF-TCLCMPGFKGVHCELEINEC 498
Query: 779 -SDPNKYGPRCNKK-----CLCVHG----TCNNRID--SDGACLTGT------------C 814
S+P +C K CLC G C ID S CL G C
Sbjct: 499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQC 558
Query: 815 RDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCS-EMDPCTG 873
G G LC++ C P CH H C+ + +CIC GY G +CS ++D C
Sbjct: 559 ATGFTGVLCEENIDNCDP--DPCH-HGQCQDGIDSYTCICNPGYM--GAICSDQIDECYS 613
Query: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTG-----NGRDCSEINNCLLPSAGGCHDNASC 928
C + CI G + C CQ G +G N DC+ N C+ G C D
Sbjct: 614 ---SPCLNDGRCIDLVNG-YQCNCQPGTSGVNCEINFDDCAS-NPCI---HGICMD---- 661
Query: 929 LYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
G + C C GF G + + I C + C A+C + +G + C+C EG
Sbjct: 662 ---GINRYSCVCSPGFTGQRCNID-IDEC--ASNPCRKGATCINGVNG-FRCICPEG 711
Score = 100 bits (248), Expect = 2e-20
Identities = 112/386 (29%), Positives = 150/386 (38%), Gaps = 79/386 (20%)
Query: 1855 LNGQTCRIVQR---ELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSC 1911
LNG TC ++ R E +G G +C D L C +T C + N SC
Sbjct: 116 LNGGTCHMLSRDTYECTCQVGFT-GKECQWTDACLSHPCANGST------CTTVANQFSC 168
Query: 1912 PRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIP-----RCCKGYFGRDCQAC--PG 1964
+ G QKC ++ + ++ G + + +P +C +G+ G+ C + P
Sbjct: 169 KCLTGFTG--QKCETDVN-ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPC 225
Query: 1965 GPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGI 2024
P +PC N G C T EC C GF G+ CE R DC C + G C DG+
Sbjct: 226 AP-SPCVNGGTCRQTGDFTFECNCLPGFEGSTCE-----RNIDDCPNHRCQNGGVCVDGV 279
Query: 2025 TGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENN---TCECNLDYEGD---- 2076
+ C C WTG C T+ V + P C TC N C C + GD
Sbjct: 280 -NTYNCRCPPQWTGQFC-TEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSE 337
Query: 2077 ------------GITC--TVVDF---CKQDNGG-------------CAKVARCSQK--GT 2104
G TC V F C + G C K A C
Sbjct: 338 NIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNG 397
Query: 2105 KVSCSCQKGYKGDGHSCTE-IDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLN 2163
+ C+C +GYK G CTE +D CA + C EHA + G CEC Y G
Sbjct: 398 QYICTCPQGYK--GADCTEDVDECAMANSNPC-EHAGKCVNTDGAFHCECLKGYAGP--R 452
Query: 2164 CEPEQLPIDRCLQDNGQCHADAKCVD 2189
CE + I+ C D C DA C+D
Sbjct: 453 CE---MDINECHSD--PCQNDATCLD 473
Score = 98.2 bits (243), Expect = 9e-20
Identities = 84/309 (27%), Positives = 110/309 (35%), Gaps = 50/309 (16%)
Query: 715 CARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQC-ADSLGGNGTCICEEGFQGS 773
C Y N T KC +GF G C N C G C A ++ G TC C GF G
Sbjct: 41 CVTYHNGTGYC-KCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGE 99
Query: 774 QCQ-------FCSDPNKYGPRCNK------KCLCVHGTCNNRIDSDGACLTGTCRDGS-- 818
CQ F S P G C+ +C C G ACL+ C +GS
Sbjct: 100 DCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTC 159
Query: 819 ---------------AGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGT 863
G+ C+ + C C TC G+ C C G+ G
Sbjct: 160 TTVANQFSCKCLTGFTGQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQ-- 216
Query: 864 LCSEM-DPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGN--GRDCSEINNCLLPSAG 920
C + PC P C C +TG T C C G+ G+ R+ + N + G
Sbjct: 217 YCDSLYVPC---APSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGG 273
Query: 921 GCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSC 980
C D G C C + G E + CL Q C +C + + G + C
Sbjct: 274 VCVD-------GVNTYNCRCPPQWTGQ-FCTEDVDECLLQPNACQNGGTCANRNGG-YGC 324
Query: 981 VCQEGYEGD 989
VC G+ GD
Sbjct: 325 VCVNGWSGD 333
Score = 95.9 bits (237), Expect = 5e-19
Identities = 99/332 (29%), Positives = 131/332 (39%), Gaps = 56/332 (16%)
Query: 42 ECRSCALNLGVKC---PDGYT-MITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQ 97
+C S G KC P+GY +G GV C + + C H +D +
Sbjct: 535 DCSSTPCLNGAKCIDHPNGYECQCATGFTGVL-CEENID----NCDPDPCHHGQCQDGID 589
Query: 98 PRCC---PGRWGPDCI----ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETC 150
C PG G C EC SPC G C + + G C+CQ G G CE
Sbjct: 590 SYTCICNPGYMGAICSDQIDEC---YSSPCLNDGRCIDLVNGY-QCNCQPGTSGVNCEIN 645
Query: 151 ADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC 210
DD P C+HG+C G++ +C C +TG +C+ I ECA+ C + + C
Sbjct: 646 FDDCASNP-------CIHGICMDGINRY-SCVCSPGFTGQRCNIDIDECASNPCRKGATC 697
Query: 211 SPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG 270
N C C Y +N CL C H +CT G + + C C G+ G
Sbjct: 698 ---INGVNGFRCICPEGPHHPSCY-SQVNECLSNPC-IHGNCTG-GLSGYKCLCDAGWVG 751
Query: 271 -----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMT-D 324
D CL +PCQ N G C + V Y C CK+ ++ G C + D
Sbjct: 752 INCEVDKNECLS-NPCQ-NGGTC--DNLVNGY------RCTCKKGFK----GYNCQVNID 797
Query: 325 ICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
C S NPC C G T C C Y G
Sbjct: 798 ECAS-NPCLNQGTCFDDISGYT-CHCVLPYTG 827
Score = 95.5 bits (236), Expect = 6e-19
Identities = 58/195 (29%), Positives = 83/195 (42%), Gaps = 17/195 (8%)
Query: 1969 PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQC-DDGITGS 2027
PC N G+C+ ++ TG CKC GF G C+ P C C + G C + G
Sbjct: 34 PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDP------CEKNRCQNGGTCVAQAMLGK 87
Query: 2028 GQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCK--ENNTCECNLDYEGDGITCTVVDF 2085
C C +G+TG C P + PC TC +T EC G C D
Sbjct: 88 ATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDA 147
Query: 2086 CKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSC-TEIDPCADGLNGGCHEHATCKMT 2144
C + CA + C+ + SC C G+ G C T+++ C + G C TC +
Sbjct: 148 CL--SHPCANGSTCTTVANQFSCKCLTGF--TGQKCETDVNEC--DIPGHCQHGGTC-LN 200
Query: 2145 GPGKHKCECKSHYVG 2159
PG ++C+C + G
Sbjct: 201 LPGSYQCQCPQGFTG 215
Score = 94.7 bits (234), Expect = 1e-18
Identities = 77/256 (30%), Positives = 100/256 (39%), Gaps = 34/256 (13%)
Query: 739 QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGT 798
QC G+ PC G C G G C C EGF G CQ DP C K GT
Sbjct: 27 QCRDGYE-PCVNEGMCVTYHNGTGYCKCPEGFLGEYCQH-RDP------CEKNRCQNGGT 78
Query: 799 CNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE-YSNGTASCICKAG 857
C + A T C G G C TS + C TC S T C C+ G
Sbjct: 79 CVAQAMLGKA--TCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVG 136
Query: 858 YEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLP 917
+ G C D C C+ + C T +C C G+TG + +++N C +P
Sbjct: 137 FTGKE--CQWTDACLS---HPCANGSTC-TTVANQFSCKCLTGFTGQKCE-TDVNECDIP 189
Query: 918 SAGGCHDNASCLYVGPGQNECECKKGFRGNGID-----CEPITSCLEQTGKCHPLASCQS 972
G C +CL + PG +C+C +GF G D C P C +C+
Sbjct: 190 --GHCQHGGTCLNL-PGSYQCQCPQGFTGQYCDSLYVPCAP--------SPCVNGGTCRQ 238
Query: 973 TSSGVWSCVCQEGYEG 988
T + C C G+EG
Sbjct: 239 TGDFTFECNCLPGFEG 254
Score = 94.7 bits (234), Expect = 1e-18
Identities = 96/337 (28%), Positives = 135/337 (40%), Gaps = 40/337 (11%)
Query: 667 ETKREMKLGTCVSCSLVYWSRCPANSEPTA-----LFTHRCVYSGRFGSLKSGCARYCNA 721
E R GTCV+ +++ + C S T +H C S L G +
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRP--CLNGGTCHMLSR 126
Query: 722 TVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP 781
C GF G +C S+PC+ NG ++ +C C GF G +C+ +D
Sbjct: 127 DTYECTCQVGFTGKECQWTDACLSHPCA-NGSTCTTVANQFSCKCLTGFTGQKCE--TDV 183
Query: 782 NKYGPRCNKKCLCVH-GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIH 840
N+ C+ C H GTC N + C C G G+ CD C P C
Sbjct: 184 NE----CDIPGHCQHGGTCLN-LPGSYQC---QCPQGFTGQYCDSLYVPCAP--SPCVNG 233
Query: 841 ATCEYSNG-TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQ 899
TC + T C C G+EG T +D C C C+ G T+ C C
Sbjct: 234 GTCRQTGDFTFECNCLPGFEG-STCERNIDDCPN---HRCQNGGVCV-DGVNTYNCRCPP 288
Query: 900 GWTGNGRDCSE-INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC-EPITSC 957
WT G+ C+E ++ CLL C + +C G C C G+ G+ DC E I C
Sbjct: 289 QWT--GQFCTEDVDECLL-QPNACQNGGTCANRNGGYG-CVCVNGWSGD--DCSENIDDC 342
Query: 958 LEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCY 994
C P ++C + +SC+C EG G LC+
Sbjct: 343 --AFASCTPGSTCIDRVAS-FSCMCPEGKA--GLLCH 374
Score = 94.7 bits (234), Expect = 1e-18
Identities = 83/295 (28%), Positives = 115/295 (38%), Gaps = 63/295 (21%)
Query: 1342 GPQCQPCPGN------------AQNVCFGNGICLDGVNGTGVCECGEGFSGTACE----- 1384
G QC PG A N C +GIC+DG+N C C GF+G C
Sbjct: 628 GYQCNCQPGTSGVNCEINFDDCASNPCI-HGICMDGINRYS-CVCSPGFTGQRCNIDIDE 685
Query: 1385 ----------TCTEGKYGIHC-------DQAC----------SCVHGRCNQGPLGDGSCD 1417
TC G G C +C C+HG C G L C
Sbjct: 686 CASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGG-LSGYKCL 744
Query: 1418 CDVGWRGVHCDNATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACE 1476
CD GW G++C+ ++ C + C C N C C GF+G +N E
Sbjct: 745 CDAGWVGINCE--VDKNECLSNPCQNGGTC-DNLVNGYRCTCKKGFKGYN---CQVNIDE 798
Query: 1477 ISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
++ C + C G C C YTG + + PC N C+ A C ++ PN
Sbjct: 799 CASNPCLNQGTCFDDISG-YTCHCVLPYTGKNCQTV-LAPCSPN--PCENAAVCKES-PN 853
Query: 1537 QAACNCLPAYTGDGKVCTL-INVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
+ CL A G+ CT+ I+ C++K C +C++T Q C C P + G
Sbjct: 854 FESYTCLCAPGWQGQRCTIDIDECISK--PCMNHGLCHNT-QGSYMCECPPGFSG 905
Score = 93.6 bits (231), Expect = 2e-18
Identities = 86/332 (25%), Positives = 120/332 (36%), Gaps = 82/332 (24%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
KC GF G C N+C C G C + L G+ C C +GF G C P
Sbjct: 169 KCLTGFTGQKCETDVNECD--IPGHCQHGGTCLN-LPGSYQCQCPQGFTGQYCDSLYVPC 225
Query: 783 KYGPRCNK-----------KCLCVHG----TC--------NNRIDSDGACLTGT------ 813
P N +C C+ G TC N+R + G C+ G
Sbjct: 226 APSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCR 285
Query: 814 CRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSE-MDPC- 871
C G+ C + C C TC NG C+C G+ GD CSE +D C
Sbjct: 286 CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDD--CSENIDDCA 343
Query: 872 -TGLTPGG---------------------CSRNAECIKTG------------TGTHTCVC 897
TPG C + CI G + C C
Sbjct: 344 FASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTC 403
Query: 898 QQGWTGNGRDCSE-INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITS 956
QG+ G DC+E ++ C + ++ C C+ G CEC KG+ G + + I
Sbjct: 404 PQGY--KGADCTEDVDECAMANSNPCEHAGKCVNT-DGAFHCECLKGYAGPRCEMD-INE 459
Query: 957 CLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
C + C A+C G ++C+C G++G
Sbjct: 460 C--HSDPCQNDATCLDKIGG-FTCLCMPGFKG 488
Score = 90.9 bits (224), Expect = 1e-17
Identities = 97/353 (27%), Positives = 145/353 (41%), Gaps = 61/353 (17%)
Query: 673 KLGTCVSCSLVYWSRCPAN-------SEPTALFTHRCVYSGRFGSLKSGCARYCNATVKI 725
K TC++ + CP S+ ++ C++ G L SG C+A
Sbjct: 693 KGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGL-SGYKCLCDA---- 747
Query: 726 PKCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDP 781
G+ G +C N+C SNPC G C D+L C C++GF+G CQ D
Sbjct: 748 -----GWVGINCEVDKNEC---LSNPCQNGGTC-DNLVNGYRCTCKKGFKGYNCQVNIDE 798
Query: 782 NKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHA 841
P N+ GTC + I T C G+ C + C P C A
Sbjct: 799 CASNPCLNQ------GTCFDDISG----YTCHCVLPYTGKNCQTVLAPCSP--NPCENAA 846
Query: 842 TCEYSNGTAS--CICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQ 899
C+ S S C+C G++G ++D C C + C T G++ C C
Sbjct: 847 VCKESPNFESYTCLCAPGWQGQ-RCTIDIDECISKP---CMNHGLCHNT-QGSYMCECPP 901
Query: 900 GWTGNGRDCSE-INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCL 958
G+ +G DC E I++CL A C + SC+ G C C GF G+ + + CL
Sbjct: 902 GF--SGMDCEEDIDDCL---ANPCQNGGSCM-DGVNTFSCLCLPGFTGDKCQTD-MNECL 954
Query: 959 EQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAAVELSFLSEAAIFN 1011
+ C +C S ++C CQ G+ DG C N ++ +E++ FN
Sbjct: 955 SE--PCKNGGTC-SDYVNSYTCKCQAGF--DGVHCENN----INECTESSCFN 998
Score = 90.5 bits (223), Expect = 2e-17
Identities = 97/358 (27%), Positives = 126/358 (35%), Gaps = 86/358 (24%)
Query: 1905 CVNTPSCPRWSKPKG--------VKQKCLYNLPFKRNLEGCRERCSLVIQIP------RC 1950
CVN C + G + + C + P ++N C+ + V Q RC
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNR--CQNGGTCVAQAMLGKATCRC 92
Query: 1951 CKGYFGRDCQACPGGP---DAPCNNRGVCLDQYSATGECKCNTGFNGTACE--------- 1998
G+ G DCQ P PC N G C T EC C GF G C+
Sbjct: 93 ASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHP 152
Query: 1999 ----------------MCWPGRFGPDC--------LPCGCSDHGQCDDGITGSGQCLCET 2034
C G G C +P C G C + + GS QC C
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLN-LPGSYQCQCPQ 211
Query: 2035 GWTGPSCDTQAVLPAVCTP-PCSAHATCKENN--TCECNLDYEGDGITC-TVVDFCKQDN 2090
G+TG CD+ L C P PC TC++ T ECN +G TC +D C N
Sbjct: 212 GFTGQYCDS---LYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC--PN 266
Query: 2091 GGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTE-IDPCADGLNGGCHEHATCKMTGPGKH 2149
C C +C C + G CTE +D C N C TC G +
Sbjct: 267 HRCQNGGVCVDGVNTYNCRCPPQW--TGQFCTEDVDECLLQPN-ACQNGGTCANRN-GGY 322
Query: 2150 KCECKSHYVGDG----------LNCEPEQLPIDR-----CLQDNGQ----CHADAKCV 2188
C C + + GD +C P IDR C+ G+ CH D C+
Sbjct: 323 GCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACI 380
Score = 89.4 bits (220), Expect = 4e-17
Identities = 76/261 (29%), Positives = 105/261 (40%), Gaps = 45/261 (17%)
Query: 118 SPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDG 177
+PC G+C + G C+C++GF G C+ D+ C+S G C + G
Sbjct: 764 NPCQNGGTCDNLVNGY-RCTCKKGFKGYNCQVNIDE------CASNPCLNQGTCFDDISG 816
Query: 178 DGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDP 237
TC C YTG C + C+ C + C S E+ C C P ++G D
Sbjct: 817 Y-TCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFES-YTCLCAPGWQGQRCTID- 873
Query: 238 INPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG-----DGQVCLPVDPCQINFGNCPTKS 292
I+ C+ K C H C + + C C G+ G D CL +PCQ N G+C
Sbjct: 874 IDECISKPCMNHGLC-HNTQGSYMCECPPGFSGMDCEEDIDDCL-ANPCQ-NGGSC---- 926
Query: 293 TVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD------NPCHRNANCTTVAPGRT 346
DG C C +PG D C++D PC C+ T
Sbjct: 927 ----MDGVNTFSCLC-------LPGF---TGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
Query: 347 ECICQKGYVGDGLTCYGNIME 367
C CQ G+ DG+ C NI E
Sbjct: 973 -CKCQAGF--DGVHCENNINE 990
Score = 89.4 bits (220), Expect = 4e-17
Identities = 76/270 (28%), Positives = 113/270 (41%), Gaps = 32/270 (11%)
Query: 727 KCCKGFYGPDCNQ-CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
+C GF G DC + +NPC G C D + +C+C GF G +CQ +D N+
Sbjct: 898 ECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVN-TFSCLCLPGFTGDKCQ--TDMNE-- 952
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEY 845
C + GTC++ ++S T C+ G G C+ + C C TC
Sbjct: 953 --CLSEPCKNGGTCSDYVNS----YTCKCQAGFDGVHCENNINECTE--SSCFNGGTCVD 1004
Query: 846 SNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNG 905
+ SC+C G+ G L E++ C+ C C+ G GT+ C C G+T G
Sbjct: 1005 GINSFSCLCPVGFTGSFCL-HEINECSS---HPCLNEGTCV-DGLGTYRCSCPLGYT--G 1057
Query: 906 RDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCH 965
++C + N L S C + +C+ +++C C G+ G D P SC +
Sbjct: 1058 KNCQTLVN--LCSRSPCKNKGTCVQ-KKAESQCLCPSGWAGAYCDV-PNVSCDIAASRRG 1113
Query: 966 PLASCQSTSSGV-------WSCVCQEGYEG 988
L SGV C C GY G
Sbjct: 1114 VLVEHLCQHSGVCINAGNTHYCQCPLGYTG 1143
Score = 87.0 bits (214), Expect = 2e-16
Identities = 74/259 (28%), Positives = 98/259 (37%), Gaps = 26/259 (10%)
Query: 110 IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHG 169
++C G PC G C G G C C EGF G C+ D C + CV
Sbjct: 26 LQCRDGY-EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ--HRDPCEKNRCQNGGTCV-- 80
Query: 170 VCNSGLDGDGTCECYSAYTGPKCDKPI--PECAALLCPENSRCSPSTEDENKLECKCLPN 227
+ G TC C S +TG C P + C C + D EC C
Sbjct: 81 --AQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD--TYECTCQVG 136
Query: 228 YRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVC-LPVDPCQINFG 286
+ GK C + CL C + CT + N+ SC C G+ GQ C V+ C I G
Sbjct: 137 F--TGKECQWTDACLSHPCANGSTCTTVA-NQFSCKCLTGF--TGQKCETDVNECDIP-G 190
Query: 287 NCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRT 346
+C T PG C+C + + G C + + +PC C
Sbjct: 191 HCQHGGTCLNL--PGSYQCQCPQGF----TGQYCDSLYVPCAPSPCVNGGTCRQTGDFTF 244
Query: 347 ECICQKGYVGDGLTCYGNI 365
EC C G+ +G TC NI
Sbjct: 245 ECNCLPGF--EGSTCERNI 261
Score = 84.7 bits (208), Expect = 1e-15
Identities = 90/374 (24%), Positives = 124/374 (33%), Gaps = 84/374 (22%)
Query: 1268 QKNRCDNNDTTII-----RGRCRTCSSELT---CPFGTKSLGNEKRRCIY--TSYFMGRR 1317
+KNRC N T + + CR C+S T C + T R C+ T + + R
Sbjct: 69 EKNRCQNGGTCVAQAMLGKATCR-CASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRD 127
Query: 1318 TLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEG 1377
T CQ GF G +CQ + C C N C+C G
Sbjct: 128 TYECTCQ-------------VGFTGKECQWTDACLSHPCANGSTCTTVANQFS-CKCLTG 173
Query: 1378 FSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN 1437
F+G CET CD C HG G C C G+ G +CD+
Sbjct: 174 FTGQKCETDVN-----ECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYV-PCAP 227
Query: 1438 GTCHTSANCLTNSDGTASCKCAAGFQG----------------NGTICT----------- 1470
C C D T C C GF+G NG +C
Sbjct: 228 SPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCP 287
Query: 1471 ----------AINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN 1520
++ C + C C G C C G++GD C EN
Sbjct: 288 PQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYG-CVCVNGWSGD--------DCSEN 338
Query: 1521 HGGCDKNAECTQTG---PNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICN-HTG 1576
C A CT A+ +C+ G +C L + C+ + C + A+C+ +
Sbjct: 339 IDDC-AFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACI--SNPCHKGALCDTNPL 395
Query: 1577 QVERTCTCKPNYIG 1590
+ CTC Y G
Sbjct: 396 NGQYICTCPQGYKG 409
Score = 84.7 bits (208), Expect = 1e-15
Identities = 69/257 (26%), Positives = 95/257 (36%), Gaps = 33/257 (12%)
Query: 118 SPCNGRGSCAEGMEGNG-TCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLD 176
+PC C E TC C G+ G C D+ + P + HG+C++
Sbjct: 840 NPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMN------HGLCHN-TQ 892
Query: 177 GDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD 236
G CEC ++G C++ I +C A C C + N C CLP + GD D
Sbjct: 893 GSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSC---MDGVNTFSCLCLPGFTGDKCQTD 949
Query: 237 PINPCLRKICHPHAHCT-YLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKST-- 293
+N CL + C C+ Y+ N ++C CQ G+ G C+ N C S
Sbjct: 950 -MNECLSEPCKNGGTCSDYV--NSYTCKCQAGFDG--------VHCENNINECTESSCFN 998
Query: 294 --VCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQ 351
C DG C C + G C S +PC C G C C
Sbjct: 999 GGTC-VDGINSFSCLCPVGF----TGSFCLHEINECSSHPCLNEGTCVD-GLGTYRCSCP 1052
Query: 352 KGYVGDGLTCYGNIMER 368
GY G N+ R
Sbjct: 1053 LGYTGKNCQTLVNLCSR 1069
Score = 84.0 bits (206), Expect = 2e-15
Identities = 89/314 (28%), Positives = 112/314 (35%), Gaps = 72/314 (22%)
Query: 100 CCPGRWGPDCI----ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACET----CA 151
C PG G C EC PC G+C++ + TC CQ GF G CE C
Sbjct: 937 CLPGFTGDKCQTDMNEC---LSEPCKNGGTCSDYVNSY-TCKCQAGFDGVHCENNINECT 992
Query: 152 DDNLF-GPSCSSVCN--------------CVHGV--CNSG--------LDGDGT--CECY 184
+ + F G +C N C+H + C+S +DG GT C C
Sbjct: 993 ESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCP 1052
Query: 185 SAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPIN----- 239
YTG C + C+ C C + K E +CL G YCD N
Sbjct: 1053 LGYTGKNCQTLVNLCSRSPCKNKGTCV-----QKKAESQCLCPSGWAGAYCDVPNVSCDI 1107
Query: 240 ------PCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVC-LPVDPCQINFGNCPTKS 292
+ +C C G N H C C GY G C +D C N P +
Sbjct: 1108 AASRRGVLVEHLCQHSGVCINAG-NTHYCQCPLGY--TGSYCEEQLDECASN----PCQH 1160
Query: 293 TVCKYDGPGQSHCECKEHYQNFVPGVGCSM-TDICKSDNPCHRNANCTTVAPGRTECICQ 351
D G CEC YQ GV C D C+ + PC C + +C C
Sbjct: 1161 GATCSDFIGGYRCECVPGYQ----GVNCEYEVDECQ-NQPCQNGGTCIDLV-NHFKCSCP 1214
Query: 352 KGYVGDGLTCYGNI 365
G GL C NI
Sbjct: 1215 PG--TRGLLCEENI 1226
Score = 82.4 bits (202), Expect = 5e-15
Identities = 98/407 (24%), Positives = 137/407 (33%), Gaps = 96/407 (23%)
Query: 1950 CCKGYFGRDCQACPGGPDA-PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C KGY G C+ + PC N CLD+ C C GF G CE+ +
Sbjct: 444 CLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGF-TCLCMPGFKGVHCELEIN-----E 497
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSC----DTQAVLPAV-------------- 2050
C C ++GQC D + QCLC G+TGP C D + P +
Sbjct: 498 CQSNPCVNNGQCVDKVNRF-QCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYEC 556
Query: 2051 -----------------CTPPCSAHATCK---ENNTCECNLDYEGDGITCTVVDFCKQDN 2090
C P H C+ ++ TC CN Y G I +D C +
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMG-AICSDQIDECY--S 613
Query: 2091 GGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADG--LNGGCHEHATCKMTGPGK 2148
C RC C+CQ G G D CA ++G C M G +
Sbjct: 614 SPCLNDGRCIDLVNGYQCNCQPGTSGVNCE-INFDDCASNPCIHGIC-------MDGINR 665
Query: 2149 HKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLG- 2207
+ C C + G N + ID C + C A C++ V F P G
Sbjct: 666 YSCVCSPGFTGQRCN-----IDIDECA--SNPCRKGATCIN------GVNGFRCICPEGP 712
Query: 2208 QYKLTFDKAREACANEAATMATYNQLSYAQKAKYHLCSAGWLETGRVAYPTAFASQNCGS 2267
+ + + E +N + + LC AGW+ S C +
Sbjct: 713 HHPSCYSQVNECLSNP----CIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQN 768
Query: 2268 GVVGIVDYGPRPNKSEMWDVFCYRMKDVNCTCKVGYVGDGFSCSGNL 2314
G G D + CTCK G+ G++C N+
Sbjct: 769 G--GTCD---------------NLVNGYRCTCKKGF--KGYNCQVNI 796
Score = 82.4 bits (202), Expect = 5e-15
Identities = 94/367 (25%), Positives = 137/367 (37%), Gaps = 65/367 (17%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C KG+ G +CQ C P C N+G C D S C C + G C+
Sbjct: 783 CKKGFKGYNCQVNIDECASNP---CLNQGTCFDDISGY-TCHCVLPYTGKNCQTVLA--- 835
Query: 2006 GPDCLPCGCSDHGQCDDGIT-GSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN 2064
C P C + C + S CLC GW G C + + PC H C
Sbjct: 836 --PCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTID--IDECISKPCMNHGLCHNT 891
Query: 2065 N---TCECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS 2120
CEC + G+ C +D C + C C SC C G+ GD
Sbjct: 892 QGSYMCECPPGF--SGMDCEEDIDDCLAN--PCQNGGSCMDGVNTFSCLCLPGFTGD--K 945
Query: 2121 C-TEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNG 2179
C T+++ C L+ C TC + C+C++ + DG++CE I+ C + +
Sbjct: 946 CQTDMNEC---LSEPCKNGGTCS-DYVNSYTCKCQAGF--DGVHCENN---INECTESS- 995
Query: 2180 QCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKA 2239
C CVD + F P+G + +F C +E N+ S
Sbjct: 996 -CFNGGTCVD------GINSFSCLCPVG-FTGSF------CLHE------INECSSHPCL 1035
Query: 2240 KYHLCSAGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMK-DVNCT 2298
C G L T R + P + +NC + +V + P NK C + K + C
Sbjct: 1036 NEGTCVDG-LGTYRCSCPLGYTGKNCQT-LVNLCSRSPCKNKGT-----CVQKKAESQCL 1088
Query: 2299 CKVGYVG 2305
C G+ G
Sbjct: 1089 CPSGWAG 1095
Score = 81.3 bits (199), Expect = 1e-14
Identities = 106/423 (25%), Positives = 147/423 (34%), Gaps = 128/423 (30%)
Query: 1262 GKVLEIQKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGNEKRRCIYTSYFMGRR--TL 1319
G+ E N CD I G C+ + L P G+ + +C F G+ +L
Sbjct: 176 GQKCETDVNECD------IPGHCQHGGTCLNLP------GSYQCQC--PQGFTGQYCDSL 221
Query: 1320 FIGCQPK-CVRTVITRE---------CCAGFFGPQCQ----PCPGNAQNVCFGNGICLDG 1365
++ C P CV R+ C GF G C+ CP + C G+C+DG
Sbjct: 222 YVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR---CQNGGVCVDG 278
Query: 1366 VN---------------------------------------GTGVCECGEGFSGTACET- 1385
VN G C C G+SG C
Sbjct: 279 VNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSEN 338
Query: 1386 -------------------------CTEGKYGIHCDQACSCVHGRCNQGPLGDGS----- 1415
C EGK G+ C +C+ C++G L D +
Sbjct: 339 IDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQ 398
Query: 1416 --CDCDVGWRGVHCDNATTEDNC----NGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 1469
C C G++G C D C + C + C+ N+DG C+C G+ G
Sbjct: 399 YICTCPQGYKGADCTEDV--DECAMANSNPCEHAGKCV-NTDGAFHCECLKGYAGPRCEM 455
Query: 1470 TAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVC-LEINPCLENHGGCDKNA 1528
IN C + C A C G C C G+ G+ C LEIN C N C N
Sbjct: 456 D-INECH--SDPCQNDATCLDKI-GGFTCLCMPGF--KGVHCELEINECQSN--PCVNNG 507
Query: 1529 ECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC-NHTGQVERTCTCKPN 1587
+C N+ C C P +T G VC I++ + C A C +H E C C
Sbjct: 508 QCVDK-VNRFQCLCPPGFT--GPVCQ-IDIDDCSSTPCLNGAKCIDHPNGYE--CQCATG 561
Query: 1588 YIG 1590
+ G
Sbjct: 562 FTG 564
Score = 80.9 bits (198), Expect = 2e-14
Identities = 82/327 (25%), Positives = 121/327 (37%), Gaps = 70/327 (21%)
Query: 1333 TRECCAGFFGPQCQPCPGNA-QNVCFGNGICLDGVNGTGVCECGEGFSGTAC-------- 1383
T +C AGF G C+ ++ CF G C+DG+N C C GF+G+ C
Sbjct: 972 TCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS-CLCPVGFTGSFCLHEINECS 1030
Query: 1384 -------ETCTEGKYGIHCD-------QACSCVHGRCNQGPL----------GDGSCDCD 1419
TC +G C + C + C++ P + C C
Sbjct: 1031 SHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCP 1090
Query: 1420 VGWRGVHCDNATTEDNCNGT---------CHTSANCLTNSDGTASCKCAAGFQGNGTICT 1470
GW G +CD + + C S C+ N+ T C+C G+ G+ C
Sbjct: 1091 SGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCI-NAGNTHYCQCPLGY--TGSYCE 1147
Query: 1471 AINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVC-LEINPCLENHGGCDKNAE 1529
E ++ C A C G R C C GY G+ C E++ C + C
Sbjct: 1148 E-QLDECASNPCQHGATCSDFIGGYR-CECVPGY--QGVNCEYEVDEC--QNQPCQNGGT 1201
Query: 1530 CTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQ-VER----TCTC 1584
C N C+C P G +C C+ C + GQ ++R +C C
Sbjct: 1202 CIDL-VNHFKCSCPPGTRG--------LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRC 1252
Query: 1585 KPNYIGDGFTCRGSIYQELPKNPKTSQ 1611
P + G+ C G I E NP +S+
Sbjct: 1253 LPGFAGE--RCEGDI-NECLSNPCSSE 1276
Score = 80.5 bits (197), Expect = 2e-14
Identities = 98/358 (27%), Positives = 133/358 (37%), Gaps = 77/358 (21%)
Query: 1336 CCAGFFGPQCQPCPGNAQNV-CFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
C GF GP CQ + + C C+D NG C+C GF+G CE + +
Sbjct: 520 CPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE-CQCATGFTGVLCEENID-----N 573
Query: 1395 CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC-NGTCHTSANCLTNSDGT 1453
CD C HG+C G + +C C+ G+ G C + D C + C C+ +G
Sbjct: 574 CDPD-PCHHGQCQDG-IDSYTCICNPGYMGAICSDQI--DECYSSPCLNDGRCIDLVNG- 628
Query: 1454 ASCKCAAGFQG----------------NGTICTAIN--ACEISNG----GCSAKADCKRT 1491
C C G G +G IN +C S G C+ D +
Sbjct: 629 YQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECAS 688
Query: 1492 TPGRRVCTCKAGYTGDGIVCLE----------INPCLEN---HGGCDKNAECTQTGPNQA 1538
P R+ TC G G +C E +N CL N HG C G +
Sbjct: 689 NPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNC-------TGGLSGY 741
Query: 1539 ACNCLPAYTG-----DGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGF 1593
C C + G D C L N C +NGG + + + CTCK + G+
Sbjct: 742 KCLCDAGWVGINCEVDKNEC-LSNPC--QNGGTCDNLVNGY------RCTCKKGF--KGY 790
Query: 1594 TCRGSIYQELPKNPKTSQ--YFFQLQE---HFVKDLVGPGPFTVFAPLSAAFDEEARV 1646
C+ +I E NP +Q F + H V G TV AP S E A V
Sbjct: 791 NCQVNI-DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAV 847
Score = 79.3 bits (194), Expect = 4e-14
Identities = 85/310 (27%), Positives = 125/310 (40%), Gaps = 49/310 (15%)
Query: 678 VSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDC 737
VSC + A S L H C +SG + +G YC +C G+ G C
Sbjct: 1103 VSCDI-------AASRRGVLVEHLCQHSGV--CINAGNTHYC-------QCPLGYTGSYC 1146
Query: 738 N-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVH 796
Q SNPC C+D +GG C C G+QG C++ D C +
Sbjct: 1147 EEQLDECASNPCQHGATCSDFIGGY-RCECVPGYQGVNCEYEVD------ECQNQPCQNG 1199
Query: 797 GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSAC--GPYVQFCHIHATCEYSNGTASCIC 854
GTC + ++ +C G+ G LC++ C GP+ C C G SC C
Sbjct: 1200 GTCIDLVNH----FKCSCPPGTRGLLCEENIDDCARGPH---CLNGGQCMDRIGGYSCRC 1252
Query: 855 KAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNC 914
G+ G+ +++ C P + +CI+ T + CVC+ +T GR C +
Sbjct: 1253 LPGFAGE-RCEGDINECLS-NPCSSEGSLDCIQL-TNDYLCVCRSAFT--GRHCETFVD- 1306
Query: 915 LLPSAGGCHDNASCLYVG--PGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQS 972
+ P C + +C P C C GF +G C+ +SC + KC C
Sbjct: 1307 VCPQM-PCLNGGTCAVASNMPDGFICRCPPGF--SGARCQ--SSCGQV--KCRKGEQCVH 1359
Query: 973 TSSGVWSCVC 982
T+SG C C
Sbjct: 1360 TASGP-RCFC 1368
Score = 79.0 bits (193), Expect = 6e-14
Identities = 83/331 (25%), Positives = 115/331 (34%), Gaps = 87/331 (26%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE---------- 1384
+C GF G C+ N +G C DG++ + C C G+ G C
Sbjct: 557 QCATGFTGVLCEENIDNCDPDPCHHGQCQDGID-SYTCICNPGYMGAICSDQIDECYSSP 615
Query: 1385 ----------------TCTEGKYGIHCD---QACS---CVHGRCNQGPLGDGSCDCDVGW 1422
C G G++C+ C+ C+HG C G + SC C G+
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDG-INRYSCVCSPGF 674
Query: 1423 RGVHCDNATTEDNCNGTCHTSANCLTNSDG----------TASC---------------K 1457
G C N ++ + C A C+ +G SC
Sbjct: 675 TGQRC-NIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGN 733
Query: 1458 CAAGFQGNGTICTA----INACEISNGGCSAK-----ADCKRTTPGRRVCTCKAGYTG-- 1506
C G G +C A IN CE+ C + C G R CTCK G+ G
Sbjct: 734 CTGGLSGYKCLCDAGWVGIN-CEVDKNECLSNPCQNGGTCDNLVNGYR-CTCKKGFKGYN 791
Query: 1507 --DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNG 1564
I NPCL N G C + + C+C+ YT GK C + + N
Sbjct: 792 CQVNIDECASNPCL-NQGTCFDDI-------SGYTCHCVLPYT--GKNCQTVLAPCSPN- 840
Query: 1565 GCSEFAICNHTGQVER-TCTCKPNYIGDGFT 1594
C A+C + E TC C P + G T
Sbjct: 841 PCENAAVCKESPNFESYTCLCAPGWQGQRCT 871
Score = 79.0 bits (193), Expect = 6e-14
Identities = 81/293 (27%), Positives = 105/293 (35%), Gaps = 47/293 (16%)
Query: 1317 RTLFIGCQPK-CVRTVITRE----------CCAGFFGPQCQ-PCPGNAQNVCFGNGICLD 1364
+T+ C P C + +E C G+ G +C C +G+C
Sbjct: 831 QTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLC-H 889
Query: 1365 GVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRG 1424
G+ +CEC GFSG CE + C SC+ G + SC C G+ G
Sbjct: 890 NTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDG------VNTFSCLCLPGFTG 943
Query: 1425 VHCD---NATTEDNC--NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISN 1479
C N + C GTC N T CKC AGF G + N E +
Sbjct: 944 DKCQTDMNECLSEPCKNGGTCSDYVNSYT-------CKCQAGFDG---VHCENNINECTE 993
Query: 1480 GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL-EINPCLENHGGCDKNAECTQTGPNQA 1538
C C C C G+TG CL EIN C + C C G
Sbjct: 994 SSCFNGGTCVDGI-NSFSCLCPVGFTGS--FCLHEINECSSH--PCLNEGTCVD-GLGTY 1047
Query: 1539 ACNCLPAYTGDGKVC-TLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
C+C YT GK C TL+N+C C C + E C C + G
Sbjct: 1048 RCSCPLGYT--GKNCQTLVNLC--SRSPCKNKGTCVQK-KAESQCLCPSGWAG 1095
Score = 79.0 bits (193), Expect = 6e-14
Identities = 78/276 (28%), Positives = 105/276 (38%), Gaps = 43/276 (15%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNK 783
C GF G C N+C S+PC G C D L G C C G+ G CQ +
Sbjct: 1013 CPVGFTGSFCLHEINECS---SHPCLNEGTCVDGL-GTYRCSCPLGYTGKNCQTLVNLCS 1068
Query: 784 YGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSAC-------GPYVQ- 835
P NK GTC + ++ CL C G AG CD +C G V+
Sbjct: 1069 RSPCKNK------GTCVQK-KAESQCL---CPSGWAGAYCDVPNVSCDIAASRRGVLVEH 1118
Query: 836 FCHIHATCEYSNGTASCICKAGYEGDGTLCSE-MDPCTGLTPGGCSRNAECIKTGTGTHT 894
C C + T C C GY G+ C E +D C C A C G +
Sbjct: 1119 LCQHSGVCINAGNTHYCQCPLGY--TGSYCEEQLDECAS---NPCQHGATC-SDFIGGYR 1172
Query: 895 CVCQQGWTGNGRDCS-EINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP 953
C C G+ G +C E++ C C + +C+ + +C C G R G+ CE
Sbjct: 1173 CECVPGY--QGVNCEYEVDEC---QNQPCQNGGTCIDL-VNHFKCSCPPGTR--GLLCEE 1224
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
+ C C G +SC C G+ G+
Sbjct: 1225 NIDDCARGPHCLNGGQCMDRIGG-YSCRCLPGFAGE 1259
Score = 76.6 bits (187), Expect = 3e-13
Identities = 93/362 (25%), Positives = 122/362 (33%), Gaps = 85/362 (23%)
Query: 1879 CLLIDPTLGGRCDTFTTFDAS------GECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKR 1932
CL + G +C T S G C VN+ +C + GV +
Sbjct: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVH--------CEN 986
Query: 1933 NLEGCRERCSLVIQIPRCCKGYFGRDCQACPGG-------------PDAPCNNRGVCLDQ 1979
N+ C E S C G C CP G PC N G C+D
Sbjct: 987 NINECTE--SSCFNGGTCVDGINSFSC-LCPVGFTGSFCLHEINECSSHPCLNEGTCVDG 1043
Query: 1980 YSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGP 2039
T C C G+ G C+ C C + G C S QCLC +GW G
Sbjct: 1044 LG-TYRCSCPLGYTGKNCQT-----LVNLCSRSPCKNKGTCVQKKAES-QCLCPSGWAGA 1096
Query: 2040 SCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARC 2099
CD N +C+ G +V+ Q +G C
Sbjct: 1097 YCDV-------------------PNVSCDIAASRRG-----VLVEHLCQHSGVCINA--- 1129
Query: 2100 SQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
G C C GY G + ++D CA + C ATC G ++CEC Y
Sbjct: 1130 ---GNTHYCQCPLGYTG-SYCEEQLDECA---SNPCQHGATCS-DFIGGYRCECVPGY-- 1179
Query: 2160 DGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREA 2219
G+NCE E +D C N C C+DL V F P G L ++ +
Sbjct: 1180 QGVNCEYE---VDEC--QNQPCQNGGTCIDL------VNHFKCSCPPGTRGLLCEENIDD 1228
Query: 2220 CA 2221
CA
Sbjct: 1229 CA 1230
Score = 75.1 bits (183), Expect = 8e-13
Identities = 70/261 (26%), Positives = 106/261 (40%), Gaps = 41/261 (15%)
Query: 1353 QNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACS--CVHGRCNQGP 1410
+++C +G+C++ N T C+C G++G+ CE D+ S C HG
Sbjct: 1117 EHLCQHSGVCINAGN-THYCQCPLGYTGSYCEE--------QLDECASNPCQHGATCSDF 1167
Query: 1411 LGDGSCDCDVGWRGVHCDNATTEDNC-NGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC 1469
+G C+C G++GV+C+ D C N C C+ + C C G +G
Sbjct: 1168 IGGYRCECVPGYQGVNCEYEV--DECQNQPCQNGGTCI-DLVNHFKCSCPPGTRG----- 1219
Query: 1470 TAINACEISNGGCSAKADCKR-----TTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGC 1524
CE + C+ C G C C G+ G+ +IN CL N
Sbjct: 1220 ---LLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEG-DINECLSNPCSS 1275
Query: 1525 DKNAECTQTGPNQAACNCLPAYTGDGKVC-TLINVCLTK---NGGCSEFAICNHTGQVER 1580
+ + +C Q N C C A+T G+ C T ++VC NGG A G +
Sbjct: 1276 EGSLDCIQL-TNDYLCVCRSAFT--GRHCETFVDVCPQMPCLNGGTCAVASNMPDGFI-- 1330
Query: 1581 TCTCKPNYIGDGFTCRGSIYQ 1601
C C P + G C+ S Q
Sbjct: 1331 -CRCPPGF--SGARCQSSCGQ 1348
Score = 69.7 bits (169), Expect = 3e-11
Identities = 69/275 (25%), Positives = 107/275 (38%), Gaps = 48/275 (17%)
Query: 118 SPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCN---CVH-GVC-N 172
SPC +G+C + + C C G+ G C+ S V C H GVC N
Sbjct: 1070 SPCKNKGTCVQ-KKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCIN 1128
Query: 173 SGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDG 232
+G C+C YTG C++ + ECA+ C + CS + C+C+P Y+G
Sbjct: 1129 AG--NTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCS---DFIGGYRCECVPGYQGVN 1183
Query: 233 KYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLP-VDPCQ-----INF 285
C+ ++ C + C C L N C+C G R G +C +D C +N
Sbjct: 1184 --CEYEVDECQNQPCQNGGTCIDL-VNHFKCSCPPGTR--GLLCEENIDDCARGPHCLNG 1238
Query: 286 GNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD------NPCHRNANCT 339
G C D G C C +PG + C+ D NPC +
Sbjct: 1239 GQC--------MDRIGGYSCRC-------LPGFA---GERCEGDINECLSNPCSSEGSLD 1280
Query: 340 TV-APGRTECICQKGYVGDGLTCYGNIMERLRELN 373
+ C+C+ + G + ++ ++ LN
Sbjct: 1281 CIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLN 1315
Score = 67.8 bits (164), Expect = 1e-10
Identities = 70/261 (26%), Positives = 94/261 (36%), Gaps = 59/261 (22%)
Query: 1950 CCKGYFGRDCQ-ACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C GY G C +PC N G C+D + +C C G +G CE+ + D
Sbjct: 595 CNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGY-QCNCQPGTSGVNCEINFD-----D 648
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATC------- 2061
C C HG C DGI C+C G+TG C+ + + PC ATC
Sbjct: 649 CASNPCI-HGICMDGINRYS-CVCSPGFTGQRCNID--IDECASNPCRKGATCINGVNGF 704
Query: 2062 --------------KENNTC-----------------ECNLDYEGDGITCTVVDFCKQDN 2090
+ N C +C D GI C V D + +
Sbjct: 705 RCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEV-DKNECLS 763
Query: 2091 GGCAKVARCSQKGTKVSCSCQKGYKGDGHSC-TEIDPCADGLNGGCHEHATCKMTGPGKH 2149
C C C+C+KG+K G++C ID CA + C TC G +
Sbjct: 764 NPCQNGGTCDNLVNGYRCTCKKGFK--GYNCQVNIDECA---SNPCLNQGTCFDDISG-Y 817
Query: 2150 KCECKSHYVGDGLNCEPEQLP 2170
C C Y G NC+ P
Sbjct: 818 TCHCVLPYTGK--NCQTVLAP 836
Score = 62.0 bits (149), Expect = 7e-09
Identities = 91/367 (24%), Positives = 124/367 (33%), Gaps = 63/367 (17%)
Query: 42 ECRSCALNLGVKCPD---GYTM-ITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQ 97
EC S G C D GY G GV +C Y + G I ++ +
Sbjct: 1152 ECASNPCQHGATCSDFIGGYRCECVPGYQGV-NCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
Query: 98 PRCCPGRWGPDCIE----CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADD 153
C PG G C E C G C G C + + G +C C GF G CE ++
Sbjct: 1211 CSCPPGTRGLLCEENIDDC--ARGPHCLNGGQCMDRI-GGYSCRCLPGFAGERCEGDINE 1267
Query: 154 NLFGPSCSSV--CNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS 211
L P CSS +C+ L D C C SA+TG C+ + C + C C+
Sbjct: 1268 CLSNP-CSSEGSLDCIQ------LTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCA 1320
Query: 212 PSTEDENKLECKCLPNYRG-------DGKYCDPINPCLRKICHPHAHCTYLGPNRHSCT- 263
++ + C+C P + G C C+ P C C
Sbjct: 1321 VASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCAS 1380
Query: 264 --CQEGYRGDGQVCLPVDPCQ----INFGNC---------PTKSTVCKY--DGPGQSHCE 306
CQ G Q P CQ + C P + + +Y D C+
Sbjct: 1381 SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCD 1440
Query: 307 --CKEHYQNFVPGVGCSMT-----DICKSDNPC--HRNANCTTVAPGRTECICQKGYVGD 357
C H + G CS+T C S PC + N C + EC+ D
Sbjct: 1441 EACNSHACQW-DGGDCSLTMENPWANCSSPLPCWDYINNQCDELC-NTVECLF------D 1492
Query: 358 GLTCYGN 364
C GN
Sbjct: 1493 NFECQGN 1499
Score = 60.5 bits (145), Expect = 2e-08
Identities = 63/241 (26%), Positives = 85/241 (35%), Gaps = 42/241 (17%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C G G C+ C GP C N G C+D+ C+C GF G CE G
Sbjct: 1213 CPPGTRGLLCEENIDDCARGPH--CLNGGQCMDRIGGYS-CRCLPGFAGERCE----GDI 1265
Query: 2006 GPDCLPCGCSDHGQCDD-GITGSGQCLCETGWTGPSCDTQA----VLPAVCTPPCSAHAT 2060
+CL CS G D +T C+C + +TG C+T +P + C+ +
Sbjct: 1266 N-ECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASN 1324
Query: 2061 CKENNTCECNLDYEGDGITCTVVDFCKQDNG--GCAKVARCSQKGTKVSCSCQKGYKGDG 2118
+ C C + G C+ G C K +C + C C D
Sbjct: 1325 MPDGFICRCPPGFSGAR--------CQSSCGQVKCRKGEQCVHTASGPRCFCPS--PRDC 1374
Query: 2119 HSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE----PEQLPIDRC 2174
S PC G G CH P + C+C + G CE P P C
Sbjct: 1375 ESGCASSPCQHG--GSCHPQRQ-----PPYYSCQCAPPF--SGSRCELYTAPPSTPPATC 1425
Query: 2175 L 2175
L
Sbjct: 1426 L 1426
Score = 56.2 bits (134), Expect = 4e-07
Identities = 64/281 (22%), Positives = 94/281 (33%), Gaps = 73/281 (25%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
+C G+ G +C ++C + PC G C D L + C C G +G C+ D
Sbjct: 1174 ECVPGYQGVNCEYEVDECQ---NQPCQNGGTCID-LVNHFKCSCPPGTRGLLCEENIDDC 1229
Query: 783 KYGPRC-----------NKKCLCVHGTCNNRIDSD-GACLTG------------------ 812
GP C C C+ G R + D CL+
Sbjct: 1230 ARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYL 1289
Query: 813 -TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTAS---CICKAGYEGD--GTLCS 866
CR GR C+ C P + C TC ++ C C G+ G + C
Sbjct: 1290 CVCRSAFTGRHCETFVDVC-PQMP-CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCG 1347
Query: 867 EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDC-SEINNCLLPSAGGCHDN 925
++ C + +C+ T +G C C + RDC S + G CH
Sbjct: 1348 QVK---------CRKGEQCVHTASGPR-CFCP-----SPRDCESGCASSPCQHGGSCHPQ 1392
Query: 926 ASCLYVGPGQNECECKKGFRGNGID------CEPITSCLEQ 960
P C+C F G+ + P +CL Q
Sbjct: 1393 RQ-----PPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQ 1428
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 104 bits (259), Expect = 1e-21
Identities = 85/288 (29%), Positives = 111/288 (38%), Gaps = 50/288 (17%)
Query: 1325 PKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE 1384
P C++ C G++GP CQ C +G D TG C C +G +C+
Sbjct: 172 PNCLQP-----CTPGYYGPACQ-------FRCQCHGAPCDPQ--TGACFCPAERTGPSCD 217
Query: 1385 -TCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTE----DNCNG- 1438
+C++G G C SC +G Q P GSC C GW G C E NC+
Sbjct: 218 VSCSQGTSGFFCPSTHSCQNGGVFQTP--QGSCSCPPGWMGTICSLPCPEGFHGPNCSQE 275
Query: 1439 -TCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG--CSAKADC---KRTT 1492
CH C T C+CA G+ G+ C + G C+ DC R
Sbjct: 276 CRCHNGGLC---DRFTGQCRCAPGYTGD----RCREECPVGRFGQDCAETCDCAPDARCF 328
Query: 1493 PGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECT-------QTGPNQAACNCLPA 1545
P C C+ G+TGD C + C + G A CT P C+CLP
Sbjct: 329 PANGACLCEHGFTGDR--CTD-RLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPG 385
Query: 1546 YTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERT---CTCKPNYIG 1590
+ G C T GC E +C H G + T C C P Y G
Sbjct: 386 WA--GLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTG 431
Score = 99.4 bits (246), Expect = 4e-20
Identities = 85/319 (26%), Positives = 115/319 (36%), Gaps = 38/319 (11%)
Query: 1291 LTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQC-QPCP 1349
L CP G + + R T C P EC G FG C + C
Sbjct: 261 LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD 320
Query: 1350 GNAQNVCF-GNGICLDGVNGTGVCECGEGFSGTAC--ETCTEGKYGIHCDQACSCVHGRC 1406
CF NG CL C GF+G C C +G YG+ C C+C
Sbjct: 321 CAPDARCFPANGACL----------CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHS 370
Query: 1407 NQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS---CKCAAGFQ 1463
+G C C GW G+HC+ + +D C CL A+ C+CA G+
Sbjct: 371 LSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGY- 429
Query: 1464 GNGTICTAINACEISNGGCSAKADCKRT---TPGRRVCTCKAGY-TGDGIVCLEINPCLE 1519
G C ++ + CSA+ C+ +P C CK G+ G+ V PC
Sbjct: 430 -TGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSV-----PCPP 483
Query: 1520 NHGGCDKNAEC-----TQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNH 1574
G NA C P AC C P + G C L GC+ C+H
Sbjct: 484 GTWGFSCNASCQCAHEAVCSPQTGACTCTPGW--HGAHCQLPCPKGQFGEGCASRCDCDH 541
Query: 1575 T---GQVERTCTCKPNYIG 1590
+ V C C+ ++G
Sbjct: 542 SDGCDPVHGRCQCQAGWMG 560
Score = 92.4 bits (228), Expect = 5e-18
Identities = 73/253 (28%), Positives = 103/253 (40%), Gaps = 59/253 (23%)
Query: 1899 SGECGSCVNTPS---------CPRWSKPKGVKQKCLYNLPFKRNLEGC---RERCSLVIQ 1946
S + G+C TP CP+ +G +C + + +GC RC
Sbjct: 503 SPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCD-----HSDGCDPVHGRC----- 552
Query: 1947 IPRCCKGYFGRDCQ-ACPGG-------PDAPCNNRGVCLDQYSATGECKCNTGFNGTACE 1998
+C G+ G C +CP G C N G CL + G C C GF G +C+
Sbjct: 553 --QCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE---NGNCVCAPGFRGPSCQ 607
Query: 1999 M-CWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPA----VCTP 2053
C PGR+G C+PC C++H C +G C C GWTGP C +Q P C
Sbjct: 608 RSCQPGRYGKRCVPCKCANHSFCH---PSNGTCYCLAGWTGPDC-SQPCPPGHWGENCAQ 663
Query: 2054 PCSAH--ATC-KENNTCECNLDYEGDGIT--CTVVDFCKQDNGGCAKVARCSQKGTKV-- 2106
C H TC ++ +C C L + G C + F C++ +C G K
Sbjct: 664 TCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTF----GANCSQPCQCG-PGEKCHP 718
Query: 2107 ---SCSCQKGYKG 2116
+C C G+ G
Sbjct: 719 ETGACVCPPGHSG 731
Score = 91.7 bits (226), Expect = 9e-18
Identities = 84/287 (29%), Positives = 110/287 (38%), Gaps = 57/287 (19%)
Query: 727 KCCKGFYGPDCNQCPGGFSNPCS-GNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
+C G +GP C++ PCS GN D +G C C G Q C P YG
Sbjct: 134 ECAPGMWGPQCDK-------PCSCGNNSSCDPK--SGVCSCPSGLQPPNCLQPCTPGYYG 184
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE- 844
P C +C C C+ GAC C G CD S G FC +C+
Sbjct: 185 PACQFRCQCHGAPCD---PQTGACF---CPAERTGPSCDVSCSQ-GTSGFFCPSTHSCQN 237
Query: 845 ---YSNGTASCICKAGYEGDGTLCSEMDPC-TGLTPGGCSRNAECIKTG---TGTHTCVC 897
+ SC C G+ GT+CS PC G CS+ C G T C C
Sbjct: 238 GGVFQTPQGSCSCPPGWM--GTICSL--PCPEGFHGPNCSQECRCHNGGLCDRFTGQCRC 293
Query: 898 QQGWTGN-----------GRDCSEINNCLLPSAGGCHDNASCL----YVGPGQNECECKK 942
G+TG+ G+DC+E +C P A N +CL + G + C
Sbjct: 294 APGYTGDRCREECPVGRFGQDCAETCDC-APDARCFPANGACLCEHGFTGDRCTDRLCPD 352
Query: 943 GFRGNGIDCE-PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
GF G+ C+ P T E + CHP+ C C G+ G
Sbjct: 353 GF--YGLSCQAPCTCDREHSLSCHPMNG---------ECSCLPGWAG 388
Score = 90.1 bits (222), Expect = 2e-17
Identities = 74/242 (30%), Positives = 100/242 (41%), Gaps = 43/242 (17%)
Query: 1944 VIQIPR----CCKGYFGRDCQA-CPGGPDAP-------CNNRGVCLDQYSATGECKCNTG 1991
V Q P+ C G+ G C CP G P C+N G+C D++ TG+C+C G
Sbjct: 240 VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLC-DRF--TGQCRCAPG 296
Query: 1992 FNGTAC-EMCWPGRFGPDCLP-CGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPA 2049
+ G C E C GRFG DC C C+ +C +G CLCE G+TG C +
Sbjct: 297 YTGDRCREECPVGRFGQDCAETCDCAPDARC---FPANGACLCEHGFTGDRCTDRLCPDG 353
Query: 2050 VCTPPCSAHATCKENNTCECNLDYEGD--------GITCTVVDFCKQD--NGGCAKVARC 2099
C A TC ++ C+ G+ G+ C + C QD GC + C
Sbjct: 354 FYGLSCQAPCTCDREHSLSCH-PMNGECSCLPGWAGLHCN--ESCPQDTHGPGCQEHCLC 410
Query: 2100 SQKG----TKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCK---MTGPGKHKCE 2152
G T C C GY G H + P G+N C +C+ P +C
Sbjct: 411 LHGGVCQATSGLCQCAPGYTGP-HCASLCPPDTYGVN--CSARCSCENAIACSPIDGECV 467
Query: 2153 CK 2154
CK
Sbjct: 468 CK 469
Score = 88.6 bits (218), Expect = 7e-17
Identities = 71/254 (27%), Positives = 101/254 (39%), Gaps = 43/254 (16%)
Query: 719 CNATVKIPKCCKGFYGPDCN-QCPGG-FSNPCSGNGQCADSLGGN---GTCICEEGFQGS 773
C+ C G++G C CP G F C+ C S G + G C C+ G+ G+
Sbjct: 502 CSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGA 561
Query: 774 QCQFCSDPNKYGPRCNKKCLCVHG-TCNNRIDSDGACLTGTCRDGSAGRLCDKQTSA--- 829
+C +G C+ C C +G TC + +G C+ C G G C +
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTC---LPENGNCV---CAPGFRGPSCQRSCQPGRY 615
Query: 830 ---CGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCT-GLTPGGCSRNAEC 885
C P C H+ C SNGT C C AG+ G CS+ PC G C++ +C
Sbjct: 616 GKRCVPCK--CANHSFCHPSNGT--CYCLAGWTGPD--CSQ--PCPPGHWGENCAQTCQC 667
Query: 886 IKTGT---GTHTCVCQQGWTGN-----------GRDCSEINNCLLPSAGGCHDNASCLYV 931
GT +C+C GWTG+ G +CS+ C CH
Sbjct: 668 HHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQ--PCQCGPGEKCHPETGACVC 725
Query: 932 GPGQNECECKKGFR 945
PG + C+ G +
Sbjct: 726 PPGHSGAPCRIGIQ 739
Score = 88.2 bits (217), Expect = 9e-17
Identities = 88/324 (27%), Positives = 118/324 (36%), Gaps = 71/324 (21%)
Query: 82 LSLPGCRHICRKDYLQPRC-------------------CPG-RWGPDC-IECPGG-AGSP 119
L P C C Y P C CP R GP C + C G +G
Sbjct: 169 LQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFF 228
Query: 120 CNGRGSCAEG---MEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGL 175
C SC G G+CSC G+ GT C + GP+CS C C + G+C+
Sbjct: 229 CPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDR-- 286
Query: 176 DGDGTCECYSAYTGPKCDKPIP------ECAALL-CPENSRCSPSTEDENKLECKCLPNY 228
G C C YTG +C + P +CA C ++RC P+ C C +
Sbjct: 287 -FTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG-----ACLCEHGF 340
Query: 229 RGD------------GKYCDPINPCLRK---ICHP-HAHCTYLGPNRHSCTCQEGYRGD- 271
GD G C C R+ CHP + C+ L P C E D
Sbjct: 341 TGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCL-PGWAGLHCNESCPQDT 399
Query: 272 -GQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDN 330
G C C ++ G C S +C+ PG + C GV CS C+
Sbjct: 400 HGPGCQEHCLC-LHGGVCQATSGLCQC-APGYTGPHCASLCPPDTYGVNCSARCSCE--- 454
Query: 331 PCHRNANCTTVAPGRTECICQKGY 354
N +P EC+C++G+
Sbjct: 455 ------NAIACSPIDGECVCKEGW 472
Score = 88.2 bits (217), Expect = 9e-17
Identities = 90/321 (28%), Positives = 119/321 (37%), Gaps = 61/321 (19%)
Query: 1321 IGCQP---KCVRTVITRECCAGFFGPQCQ-PCPG-------NAQNVCFGNGICLDGVNGT 1369
I C P +CV C G+ C PCP NA C +C T
Sbjct: 457 IACSPIDGECV-------CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQ---T 506
Query: 1370 GVCECGEGFSGTACET-CTEGKYGIHCDQACSCVHGR-CNQGPLGDGSCDCDVGWRGVHC 1427
G C C G+ G C+ C +G++G C C C H C+ P+ G C C GW G C
Sbjct: 507 GACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCD--PV-HGRCQCQAGWMGARC 563
Query: 1428 DNATTED----NCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGG-- 1481
+ E NC+ TC T N T +C CA GF+G + +C+ G
Sbjct: 564 HLSCPEGLWGVNCSNTC-TCKNGGTCLPENGNCVCAPGFRGP----SCQRSCQPGRYGKR 618
Query: 1482 -----CSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGG--CDKNAECTQTG 1534
C+ + C P C C AG+TG C + PC H G C + +C G
Sbjct: 619 CVPCKCANHSFCH---PSNGTCYCLAGWTGPD--CSQ--PCPPGHWGENCAQTCQCHHGG 671
Query: 1535 ---PNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVE---RTCTCKPNY 1588
P +C C +TG C T CS+ C + C C P +
Sbjct: 672 TCHPQDGSCICPLGWTGHH--CLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGH 729
Query: 1589 IGDGFTCRGSIYQELPKNPKT 1609
G CR I + P T
Sbjct: 730 --SGAPCRIGIQEPFTVMPTT 748
Score = 86.3 bits (212), Expect = 4e-16
Identities = 89/329 (27%), Positives = 119/329 (36%), Gaps = 80/329 (24%)
Query: 706 GRFGSLKSGCARYCNATVKIP--------KCCKGFYGPDCNQ--CPGGFSN-----PCSG 750
GRFG CA C+ C GF G C CP GF PC+
Sbjct: 309 GRFGQ---DCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 751 NGQCADSLGG-NGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVH-GTCNNRIDSDGA 808
+ + + S NG C C G+ G C + +GP C + CLC+H G C + G
Sbjct: 366 DREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQ---ATSGL 422
Query: 809 CLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA------SCICKAGYEGDG 862
C C G G C S C P + A C N A C+CK G++
Sbjct: 423 C---QCAPGYTGPHC---ASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGN 476
Query: 863 TLCSEMDPCTGLTPG-GCSRNAECIKTGT---GTHTCVCQQGWTGNGRDCSEINNCLLPS 918
CS PC T G C+ + +C T C C GW G +C LP
Sbjct: 477 --CSV--PCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHG--------AHCQLPC 524
Query: 919 -----AGGCHDNASCLY---VGPGQNECECKKGFRGN-----------GIDCEPITSCLE 959
GC C + P C+C+ G+ G G++C +C +
Sbjct: 525 PKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTC-K 583
Query: 960 QTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
G C P +G +CVC G+ G
Sbjct: 584 NGGTCLP-------ENG--NCVCAPGFRG 603
Score = 85.5 bits (210), Expect = 6e-16
Identities = 74/282 (26%), Positives = 98/282 (34%), Gaps = 53/282 (18%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS 159
C PG WG C A C C+ G C+C G+ G C+ FG
Sbjct: 481 CPPGTWGFSC-----NASCQCAHEAVCSPQ---TGACTCTPGWHGAHCQLPCPKGQFGEG 532
Query: 160 CSSVCNCVHGVCNSGLDG-DGTCECYSAYTGPKCDKPIPE------CA-ALLCPENSRCS 211
C+S C+C H + G D G C+C + + G +C PE C+ C C
Sbjct: 533 CASRCDCDH---SDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCL 589
Query: 212 PSTEDENKLECKCLPNYRGD--------GKYCDPINPCLRKICHPHAHCTYLGPNRHSCT 263
P + C C P +RG G+Y PC C H+ C P+ +C
Sbjct: 590 PENGN-----CVCAPGFRGPSCQRSCQPGRYGKRCVPCK---CANHSFCH---PSNGTCY 638
Query: 264 CQEGYRGD--GQVCLP-------VDPCQINFGN-CPTK--STVCKYDGPGQSHCECKEHY 311
C G+ G Q C P CQ + G C + S +C G C E
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGH---HCLEGC 695
Query: 312 QNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKG 353
G CS C CH PG + C+ G
Sbjct: 696 PLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIG 737
Score = 82.4 bits (202), Expect = 5e-15
Identities = 84/323 (26%), Positives = 122/323 (37%), Gaps = 90/323 (27%)
Query: 728 CCKGFYGPDCN---QCPGGFSNPCSG-------------NGQCADSLGG----------- 760
C G+YGP C QC G +P +G + C+ G
Sbjct: 178 CTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQN 237
Query: 761 -------NGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTG- 812
G+C C G+ G+ C +GP C+++C C +G +R C G
Sbjct: 238 GGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGY 297
Query: 813 ---TCRD----GSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGD---G 862
CR+ G G+ C +T C P A C +NG +C+C+ G+ GD
Sbjct: 298 TGDRCREECPVGRFGQDC-AETCDCAP-------DARCFPANG--ACLCEHGFTGDRCTD 347
Query: 863 TLCSEMDPCTGLT---PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSA 919
LC D GL+ P C R + C C GW G C+E +C +
Sbjct: 348 RLCP--DGFYGLSCQAPCTCDRE-HSLSCHPMNGECSCLPGWA--GLHCNE--SCPQDTH 400
Query: 920 G-GCHDNASCLYVGPGQ---NECECKKGFRG-----------NGIDCEPITSCLEQTGKC 964
G GC ++ CL+ G Q C+C G+ G G++C SC E C
Sbjct: 401 GPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSC-ENAIAC 459
Query: 965 HPLASCQSTSSGVWSCVCQEGYE 987
P+ CVC+EG++
Sbjct: 460 SPIDG---------ECVCKEGWQ 473
Score = 81.6 bits (200), Expect = 9e-15
Identities = 85/317 (26%), Positives = 113/317 (35%), Gaps = 76/317 (23%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIE-C 112
CPDG+ ++ + D R +SLS C C PG G C E C
Sbjct: 350 CPDGFYGLSCQAPCTCD-------REHSLSCHPMNGECS-------CLPGWAGLHCNESC 395
Query: 113 PGGAGSP-CNGRGSCAEG---MEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH 168
P P C C G +G C C G+ G C + + +G +CS+ C+C +
Sbjct: 396 PQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCEN 455
Query: 169 GVCNSGLDGDGTCECYSAYTGPKCDKPIP------EC-AALLCPENSRCSPSTEDENKLE 221
+ S +DG+ C C + C P P C A+ C + CSP T
Sbjct: 456 AIACSPIDGE--CVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTG-----A 508
Query: 222 CKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQV----CLP 277
C C P + G AHC C +G G+G C
Sbjct: 509 CTCTPGWHG-------------------AHC--------QLPCPKGQFGEGCASRCDCDH 541
Query: 278 VDPCQINFGNCPTKSTVCKYDGPG-QSHCECKEHYQNFVPGVGCSMTDICKSDNPC-HRN 335
D C G C C+ G + H C E + GV CS T CK+ C N
Sbjct: 542 SDGCDPVHGRCQ-----CQAGWMGARCHLSCPEG----LWGVNCSNTCTCKNGGTCLPEN 592
Query: 336 ANCTTVAPGRTECICQK 352
NC APG CQ+
Sbjct: 593 GNC-VCAPGFRGPSCQR 608
Score = 79.7 bits (195), Expect = 3e-14
Identities = 81/295 (27%), Positives = 107/295 (36%), Gaps = 65/295 (22%)
Query: 728 CCKGFYGPDCNQ-CPGGFSNP-------CSGNGQCADSLGGNGTCICEEGFQGSQCQFCS 779
C G+ G CN+ CP P C G C + +G C C G+ G C
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQAT---SGLCQCAPGYTGPHCASLC 438
Query: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT--SACGPYVQFC 837
P+ YG C+ +C C + + ID + C G R G+ C T +C Q
Sbjct: 439 PPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQR-GNCSVPCPPGTWGFSCNASCQCA 497
Query: 838 HIHATCEYSNGTASCICKAGYEGDGTLCSEMDPC-TGLTPGGCSRNAECIKTG--TGTH- 893
H A C S T +C C G+ G PC G GC+ +C + H
Sbjct: 498 H-EAVC--SPQTGACTCTPGWHGAHCQL----PCPKGQFGEGCASRCDCDHSDGCDPVHG 550
Query: 894 TCVCQQGWTGN-----------GRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKK 942
C CQ GW G G +CS N C C + +CL P C C
Sbjct: 551 RCQCQAGWMGARCHLSCPEGLWGVNCS--NTCT------CKNGGTCL---PENGNCVCAP 599
Query: 943 GFRGNGI--DCEP-------ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
GFRG C+P + CHP S+G +C C G+ G
Sbjct: 600 GFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHP-------SNG--TCYCLAGWTG 645
Score = 76.3 bits (186), Expect = 4e-13
Identities = 77/259 (29%), Positives = 102/259 (39%), Gaps = 72/259 (27%)
Query: 1949 RCCKGYFGRDC--QACPG--GP--DAPCN--NRGVCLDQYSATGECKCNTGFNGTAC-EM 1999
+C G+ G DC + PG GP D PC+ N C + +G C C +G C +
Sbjct: 121 QCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPK---SGVCSCPSGLQPPNCLQP 177
Query: 2000 CWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHA 2059
C PG +GP C C HG D TG+ C C TGPSCD
Sbjct: 178 CTPGYYGPAC-QFRCQCHGAPCDPQTGA--CFCPAERTGPSCD----------------V 218
Query: 2060 TCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGH 2119
+C + + G C C+ NGG + + SCSC G+ G
Sbjct: 219 SCSQGTS----------GFFCPSTHSCQ--NGGVFQT-------PQGSCSCPPGWMGTIC 259
Query: 2120 SCTEIDPCADGLNG-------GCHEHATC-KMTGPGKHKCECKSHYVGDGLNCEPEQLPI 2171
S PC +G +G CH C + TG +C C Y GD C E+ P+
Sbjct: 260 SL----PCPEGFHGPNCSQECRCHNGGLCDRFTG----QCRCAPGYTGD--RCR-EECPV 308
Query: 2172 DRCLQDNGQ---CHADAKC 2187
R QD + C DA+C
Sbjct: 309 GRFGQDCAETCDCAPDARC 327
Score = 75.9 bits (185), Expect = 5e-13
Identities = 56/184 (30%), Positives = 73/184 (39%), Gaps = 34/184 (18%)
Query: 1287 CSSELTCPFGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFGPQCQ 1346
CS+ TC G L E C+ F G P C R+ C G +G +C
Sbjct: 576 CSNTCTCKNGGTCLP-ENGNCVCAPGFRG---------PSCQRS-----CQPGRYGKRCV 620
Query: 1347 PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTAC-ETCTEGKYGIHCDQACSCVHG- 1404
PC C + C G C C G++G C + C G +G +C Q C C HG
Sbjct: 621 PCK------CANHSFCHPS---NGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGG 671
Query: 1405 RCNQGPLGDGSCDCDVGWRGVH----CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAA 1460
C+ DGSC C +GW G H C T NC+ C + + T +C C
Sbjct: 672 TCHPQ---DGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPE-TGACVCPP 727
Query: 1461 GFQG 1464
G G
Sbjct: 728 GHSG 731
Score = 72.0 bits (175), Expect = 7e-12
Identities = 64/243 (26%), Positives = 86/243 (35%), Gaps = 38/243 (15%)
Query: 1950 CCKGYFGRDC-QACPGGPDAP-------CNNRGVCLDQYSATGECKCNTGFNGTACEMCW 2001
C G+ G C ++CP P C + GVC + +G C+C G+ G C
Sbjct: 382 CLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC---QATSGLCQCAPGYTGPHCASLC 438
Query: 2002 PGRFGPDCLPCGCSDHGQCDDGITGS---GQCLCETGWTGPSCDTQAVLPAVCTPPCSAH 2058
P PD CS C++ I S G+C+C+ GW +C P C+A
Sbjct: 439 P----PDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP-PGTWGFSCNAS 493
Query: 2059 ATCKENNTCE-----CNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKG----TKVSCS 2109
C C C G C + Q GCA C C
Sbjct: 494 CQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQ 553
Query: 2110 CQKGYKGDGHSCTEIDPCADGLNG-GCHEHATCKMTG---PGKHKCECKSHYVGDGL--N 2163
CQ G+ G + C +GL G C TCK G P C C + G +
Sbjct: 554 CQAGWMGARCHLS----CPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS 609
Query: 2164 CEP 2166
C+P
Sbjct: 610 CQP 612
Score = 65.9 bits (159), Expect = 5e-10
Identities = 60/221 (27%), Positives = 81/221 (36%), Gaps = 37/221 (16%)
Query: 26 GQARRCD---RKSLLTIRTECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSL 82
G A RCD + C+ A +G +C + G GV +C T +
Sbjct: 532 GCASRCDCDHSDGCDPVHGRCQCQAGWMGARC---HLSCPEGLWGV-NCSNTCTCKNGGT 587
Query: 83 SLPG-----CRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCS 137
LP C R Q C PGR+G C+ C S C+ NGTC
Sbjct: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCH---------PSNGTCY 638
Query: 138 CQEGFGGTACETCADDNLFGPSCSSVCNCVH-GVCNSGLDGDGTCECYSAYTGPKCDKPI 196
C G+ G C +G +C+ C C H G C+ DG+C C +TG C +
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCH---PQDGSCICPLGWTGHHCLEGC 695
Query: 197 P------ECA-ALLCPENSRCSPSTEDENKLECKCLPNYRG 230
P C+ C +C P T C C P + G
Sbjct: 696 PLGTFGANCSQPCQCGPGEKCHPETG-----ACVCPPGHSG 731
Score = 65.5 bits (158), Expect = 7e-10
Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 42/198 (21%)
Query: 701 RCVYSGRFGSLKSGCARYC---NATVKIPK-----CCKGFYGPDCNQC--PGGFSN---- 746
RC S G C+ C N +P+ C GF GP C + PG +
Sbjct: 562 RCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVP 621
Query: 747 -PCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVH-GTCNNRID 804
C+ + C S NGTC C G+ G C P +G C + C C H GTC+
Sbjct: 622 CKCANHSFCHPS---NGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCH---P 675
Query: 805 SDGACL-----TG-----TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCIC 854
DG+C+ TG C G+ G C Q CGP + CH T +C+C
Sbjct: 676 QDGSCICPLGWTGHHCLEGCPLGTFGANC-SQPCQCGP-GEKCHPE--------TGACVC 725
Query: 855 KAGYEGDGTLCSEMDPCT 872
G+ G +P T
Sbjct: 726 PPGHSGAPCRIGIQEPFT 743
Score = 63.5 bits (153), Expect = 2e-09
Identities = 59/225 (26%), Positives = 77/225 (34%), Gaps = 33/225 (14%)
Query: 1386 CTEGKYGIH--CDQACS--CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCH 1441
C G Y C C+ CVHGRC + C C GWRG C + C
Sbjct: 90 CCHGFYESRGFCVPLCAQECVHGRC----VAPNQCQCVPGWRGDDCSSECAPGMWGPQCD 145
Query: 1442 TSANCLTNSD---GTASCKCAAGFQGNGTI--CTAINACEISNGGCSAKADCKRT--TPG 1494
+C NS + C C +G Q + CT C + C P
Sbjct: 146 KPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTP----GYYGPACQFRCQCHGAPCDPQ 201
Query: 1495 RRVCTCKAGYTGDGIVCLEINPCLENHGG--CDKNAECTQTG---PNQAACNCLPAYTGD 1549
C C A TG C + G C C G Q +C+C P +
Sbjct: 202 TGACFCPAERTGPSCDV----SCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWM-- 255
Query: 1550 GKVCTLINVCLTKNGGCSEFAICNHTGQVER---TCTCKPNYIGD 1591
G +C+L CS+ C++ G +R C C P Y GD
Sbjct: 256 GTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGD 300
Score = 62.0 bits (149), Expect = 7e-09
Identities = 71/293 (24%), Positives = 102/293 (34%), Gaps = 43/293 (14%)
Query: 88 RHICRKDYLQP-RCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTA 146
R + + D+ Q +CC G + P A +GR C + C C G+ G
Sbjct: 77 RQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGR--CVAPNQ----CQCVPGWRGDD 130
Query: 147 CETCADDNLFGPSCSSVCNCVHGVCNSGLD-GDGTCECYSAYTGPKCDKPI------PEC 199
C + ++GP C C+C + NS D G C C S P C +P P C
Sbjct: 131 CSSECAPGMWGPQCDKPCSCGN---NSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPAC 187
Query: 200 AALLCPENSRCSPST------EDENKLECKCLPNYRGDGKYCDPINPCLR--KICHPHAH 251
+ C P T + C + G +C + C P
Sbjct: 188 QFRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS 247
Query: 252 CT----YLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
C+ ++G S C EG+ G C C N G C + C+ PG + C
Sbjct: 248 CSCPPGWMG-TICSLPCPEGFHGPN--CSQECRCH-NGGLCDRFTGQCRC-APGYTGDRC 302
Query: 308 KEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLT 360
+E G C+ T C D C P C+C+ G+ GD T
Sbjct: 303 REECPVGRFGQDCAETCDCAPDARCF---------PANGACLCEHGFTGDRCT 346
Score = 34.7 bits (78), Expect = 1.2
Identities = 47/215 (21%), Positives = 67/215 (31%), Gaps = 55/215 (25%)
Query: 1418 CDVGWRGVH-CDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACE 1476
C+ W G H C T T + +D +C GF + C + A E
Sbjct: 55 CERPWEGPHTCPQPTV------VYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQE 108
Query: 1477 ISNGGCSAKADCKRTTPGRR----------------------------------VCTCKA 1502
+G C A C + PG R VC+C +
Sbjct: 109 CVHGRCVAPNQC-QCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPS 167
Query: 1503 GYTGDGIVCLEINPCLENHGG--CDKNAEC--TQTGPNQAACNCLPAYTGDGKVCTLINV 1558
G CL+ PC + G C +C P AC C TG C +
Sbjct: 168 GLQPPN--CLQ--PCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPS--CDVSCS 221
Query: 1559 CLTKNGGCSEFAICNHTGQVER---TCTCKPNYIG 1590
T C C + G + +C+C P ++G
Sbjct: 222 QGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMG 256
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 103 bits (258), Expect = 2e-21
Identities = 83/273 (30%), Positives = 114/273 (41%), Gaps = 45/273 (16%)
Query: 745 SNPCSGNGQCADSLGGNGTCICEEGFQGSQC----QFC-SDPNKYGPRC-----NKKCLC 794
SN C +G+C GG TC C +GF G+ C C S+P + G C + KC+C
Sbjct: 596 SNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655
Query: 795 VHG----TCNNRID--SDGACLT-GTCRD-----------GSAGRLCDKQTSACGPYVQF 836
G C I+ S C GTCRD G G+ C + S C
Sbjct: 656 SDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEAT-- 713
Query: 837 CHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCV 896
C+ TC C+C G+EG + C P C C+ G + TCV
Sbjct: 714 CNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC---LPNPCHNGGTCVVNGE-SFTCV 769
Query: 897 CQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE-PIT 955
C++GW G C++ N P C+++ +C+ G CEC GF G DC I
Sbjct: 770 CKEGW--EGPICAQNTNDCSPHP--CYNSGTCV-DGDNWYRCECAPGFAGP--DCRININ 822
Query: 956 SCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
C Q+ C A+C +G + CVC G+ G
Sbjct: 823 EC--QSSPCAFGATCVDEING-YRCVCPPGHSG 852
Score = 92.8 bits (229), Expect = 4e-18
Identities = 85/291 (29%), Positives = 118/291 (40%), Gaps = 57/291 (19%)
Query: 728 CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFC-SDPNKY 784
C +G+ GP+CN+ C G S +G C G C C+ G+QG C C P
Sbjct: 220 CMEGWMGPECNRAICRQGCSPK---HGSCKLP----GDCRCQYGWQGLYCDKCIPHPGCV 272
Query: 785 GPRCNK--KCLC-----------------VH------GTCNNRIDSDGACLTGTCRDGSA 819
CN+ +CLC H GTC+N C +C +G +
Sbjct: 273 HGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQC---SCPEGYS 329
Query: 820 GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC 879
G C+ AC CH +C+ ++ C C G+ G T + +D C +P C
Sbjct: 330 GPNCEIAEHAC--LSDPCHNRGSCKETSLGFECECSPGWTGP-TCSTNIDDC---SPNNC 383
Query: 880 SRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCHDNASCLYVGPGQNEC 938
S C G CVC WT G+ C + N C A C + SC + C
Sbjct: 384 SHGGTCQDLVNG-FKCVCPPQWT--GKTCQLDANEC---EAKPCVNAKSCKNL-IASYYC 436
Query: 939 ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
+C G+ G D I CL G+C ASC+ +G + C+C GY GD
Sbjct: 437 DCLPGWMGQNCDIN-INDCL---GQCQNDASCRDLVNG-YRCICPPGYAGD 482
Score = 89.7 bits (221), Expect = 3e-17
Identities = 100/376 (26%), Positives = 127/376 (33%), Gaps = 109/376 (28%)
Query: 85 PGCRH-ICRKDYLQPRC-CPGRWG-----PDCIECPGGAGSPCNGRGSCAEGMEGNGTCS 137
PGC H IC + + +C C WG D C G PC G+C+ CS
Sbjct: 269 PGCVHGICNEPW---QCLCETNWGGQLCDKDLNYC--GTHQPCLNGGTCSNTGPDKYQCS 323
Query: 138 CQEGFGGTACE---------------TCADDNL----------FGPSCS------SVCNC 166
C EG+ G CE +C + +L GP+CS S NC
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNC 383
Query: 167 VHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLP 226
HG L C C +TG C EC A C C C CLP
Sbjct: 384 SHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIA---SYYCDCLP 440
Query: 227 NYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD----------GQVC 275
+ G CD IN CL + C A C L N + C C GY GD C
Sbjct: 441 GWMGQN--CDININDCLGQ-CQNDASCRDL-VNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 276 LPVDPCQINFGN----CPT--KSTVCKYD------GPGQS-----------HCECKE--- 309
L CQ CPT +C+ D P Q+ C+C E
Sbjct: 497 LNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYE 556
Query: 310 -----HYQNFVPGVGCSMTDICK---------------SDNPCHRNANCTTVAPGRTECI 349
H ++ C + D C S N C + C + + G+ C
Sbjct: 557 GKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCD 616
Query: 350 CQKGYVGDGLTCYGNI 365
C KG+ G C+ NI
Sbjct: 617 CNKGFT--GTYCHENI 630
Score = 85.9 bits (211), Expect = 5e-16
Identities = 89/318 (27%), Positives = 113/318 (35%), Gaps = 76/318 (23%)
Query: 86 GCRHICRK--DYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGN-------GTC 136
GC CR D+ C C+E G G CN R C +G G C
Sbjct: 195 GCNKFCRPRDDFFGHYACDQNGNKTCME--GWMGPECN-RAICRQGCSPKHGSCKLPGDC 251
Query: 137 SCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPI 196
CQ G+ G C+ C CVHG+CN C C + + G CDK +
Sbjct: 252 RCQYGWQGLYCDKCIPHP----------GCVHGICNE----PWQCLCETNWGGQLCDKDL 297
Query: 197 PECAA-LLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINPCLRKICHPHAHC-- 252
C C CS + D K +C C Y G C+ + CL CH C
Sbjct: 298 NYCGTHQPCLNGGTCSNTGPD--KYQCSCPEGYSGPN--CEIAEHACLSDPCHNRGSCKE 353
Query: 253 TYLG----------------------PNR--HSCTCQEGYRGDGQVCLPV---DPCQINF 285
T LG PN H TCQ+ G VC P CQ++
Sbjct: 354 TSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDA 413
Query: 286 GNCPTKSTV----CKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD--NPCHRNANCT 339
C K V CK + +C+C +PG DI +D C +A+C
Sbjct: 414 NECEAKPCVNAKSCK-NLIASYYCDC-------LPGWMGQNCDININDCLGQCQNDASCR 465
Query: 340 TVAPGRTECICQKGYVGD 357
+ G CIC GY GD
Sbjct: 466 DLVNG-YRCICPPGYAGD 482
Score = 83.2 bits (204), Expect = 3e-15
Identities = 64/228 (28%), Positives = 85/228 (37%), Gaps = 35/228 (15%)
Query: 1970 CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQ 2029
C G C Q C CN GF GT C DC C + G C DG+ S +
Sbjct: 599 CGPHGKCKSQSGGKFTCDCNKGFTGTYCH-----ENINDCESNPCRNGGTCIDGV-NSYK 652
Query: 2030 CLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE---NNTCECNLDYEGDGITCTVVDFC 2086
C+C GW G C+T + PC TC++ + C+C ++G TC D
Sbjct: 653 CICSDGWEGAYCETN--INDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGK--TCHSRD-S 707
Query: 2087 KQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGP 2146
+ D C C +G C C G++G + C L CH TC + G
Sbjct: 708 QCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC---LPNPCHNGGTCVVNGE 764
Query: 2147 GKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQ-----CHADAKCVD 2189
C CK + G PI C Q+ C+ CVD
Sbjct: 765 -SFTCVCKEGWEG----------PI--CAQNTNDCSPHPCYNSGTCVD 799
Score = 82.4 bits (202), Expect = 5e-15
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 21/227 (9%)
Query: 1957 RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSD 2016
+D C G PC N G C + +C C G++G CE+ CL C +
Sbjct: 295 KDLNYC--GTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHA-----CLSDPCHN 347
Query: 2017 HGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKE-NNTCECNLDYE 2074
G C + G +C C GWTGP+C T C+P CS TC++ N +C +
Sbjct: 348 RGSCKETSLGF-ECECSPGWTGPTCSTNI---DDCSPNNCSHGGTCQDLVNGFKCVCPPQ 403
Query: 2075 GDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGG 2134
G TC +D + + C C C C G+ G + I+ C G
Sbjct: 404 WTGKTCQ-LDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQ-NCDININDCL----GQ 457
Query: 2135 CHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
C A+C+ G ++C C Y GD + ++ + CL + G C
Sbjct: 458 CQNDASCRDLVNG-YRCICPPGYAGDHCERDIDECASNPCL-NGGHC 502
Score = 81.6 bits (200), Expect = 9e-15
Identities = 76/273 (27%), Positives = 111/273 (40%), Gaps = 58/273 (21%)
Query: 1937 CRERCSLV---IQIP---RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNT 1990
CR+ CS ++P RC G+ G C C P G+C + + +C C T
Sbjct: 234 CRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCV---HGICNEPW----QCLCET 286
Query: 1991 GFNGTACEMCWPGRFGPDCLPCG----CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAV 2046
+ G C+ D CG C + G C + QC C G++GP+C+
Sbjct: 287 NWGGQLCDK--------DLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAE- 337
Query: 2047 LPAVCTPPCSAHATCKENNT---CECNLDYEGDGITC-TVVDFCKQDNGGCAKVARCSQK 2102
A + PC +CKE + CEC+ + G TC T +D C +N C+ C
Sbjct: 338 -HACLSDPCHNRGSCKETSLGFECECSPGWTGP--TCSTNIDDCSPNN--CSHGGTCQDL 392
Query: 2103 GTKVSCSCQKGYKG-----DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHY 2157
C C + G D + C E PC + +CK + C+C +
Sbjct: 393 VNGFKCVCPPQWTGKTCQLDANEC-EAKPCVNA--------KSCKNL-IASYYCDCLPGW 442
Query: 2158 VGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
+G NC+ + I+ CL GQC DA C DL
Sbjct: 443 MGQ--NCD---ININDCL---GQCQNDASCRDL 467
Score = 81.3 bits (199), Expect = 1e-14
Identities = 69/247 (27%), Positives = 90/247 (36%), Gaps = 50/247 (20%)
Query: 1357 FGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSC 1416
FG+ C N T C EG+ G C C Q CS HG C G C
Sbjct: 207 FGHYACDQNGNKT----CMEGWMGPECNRAI-------CRQGCSPKHGSCKL----PGDC 251
Query: 1417 DCDVGWRGVHCDNATTEDNC-NGTCHTSANCLTNSD-GTASCKCAAGFQGNGTICTAINA 1474
C GW+G++CD C +G C+ CL ++ G C + G C
Sbjct: 252 RCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCL---- 307
Query: 1475 CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG 1534
NGG C T P + C+C GY+G E + CL + C C +T
Sbjct: 308 ----NGG-----TCSNTGPDKYQCSCPEGYSGPNCEIAE-HACLSD--PCHNRGSCKETS 355
Query: 1535 PNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVER-----TCTCKPNYI 1589
C C P +TG C T CS C+H G + C C P +
Sbjct: 356 LG-FECECSPGWTGP--------TCSTNIDDCSP-NNCSHGGTCQDLVNGFKCVCPPQWT 405
Query: 1590 GDGFTCR 1596
G TC+
Sbjct: 406 GK--TCQ 410
Score = 80.9 bits (198), Expect = 2e-14
Identities = 72/265 (27%), Positives = 103/265 (38%), Gaps = 34/265 (12%)
Query: 109 CIECPGGAGSPCNGRGS-----CAEGMEGNGTCSCQEGFGGTACET--------CADDNL 155
C P G+ C R S C E EG ++ T CE ++D
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTP 588
Query: 156 FGPS--CSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPS 213
G S+VC HG C S G TC+C +TG C + I +C + C C
Sbjct: 589 EGVRYISSNVCG-PHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTC--- 644
Query: 214 TEDENKLECKCLPNYRGDGKYCDP-INPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDG 272
+ N +C C + +G YC+ IN C + CH C L N C C+ G++ G
Sbjct: 645 IDGVNSYKCICSDGW--EGAYCETNINDCSQNPCHNGGTCRDL-VNDFYCDCKNGWK--G 699
Query: 273 QVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMT-DICKSDNP 331
+ C D Q + C T YD C C ++ G C++ + NP
Sbjct: 700 KTCHSRD-SQCDEATCNNGGTC--YDEGDAFKCMCPGGWE----GTTCNIARNSSCLPNP 752
Query: 332 CHRNANCTTVAPGRTECICQKGYVG 356
CH C T C+C++G+ G
Sbjct: 753 CHNGGTCVVNGESFT-CVCKEGWEG 776
Score = 80.1 bits (196), Expect = 3e-14
Identities = 77/318 (24%), Positives = 115/318 (36%), Gaps = 73/318 (22%)
Query: 727 KCCKGFYGPDCNQCPGGFS-NPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
+C G+ GP C+ S N CS G C D + G C+C + G CQ ++ +
Sbjct: 361 ECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGF-KCVCPPQWTGKTCQLDANECEAK 419
Query: 786 PRCNKK----------CLCVHGTCNNRIDSD-----GACLT-GTCRD-----------GS 818
P N K C C+ G D + G C +CRD G
Sbjct: 420 PCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGY 479
Query: 819 AGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCS-EMDPCTGLTPG 877
AG C++ C C C+ C+C G+ G+ LC ++D C P
Sbjct: 480 AGDHCERDIDECASNP--CLNGGHCQNEINRFQCLCPTGFSGN--LCQLDIDYCE---PN 532
Query: 878 GCSRNAECIKTGTGTHTCVCQQGWTGNG----------RDCSEINNCLLPSAGG------ 921
C A+C + + C C + + G C I++C + A
Sbjct: 533 PCQNGAQCYNRASD-YFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGV 591
Query: 922 -------CHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKC--HPLASCQS 972
C + C G+ C+C KGF G T C E C +P + +
Sbjct: 592 RYISSNVCGPHGKCKSQSGGKFTCDCNKGFTG--------TYCHENINDCESNPCRNGGT 643
Query: 973 TSSGV--WSCVCQEGYEG 988
GV + C+C +G+EG
Sbjct: 644 CIDGVNSYKCICSDGWEG 661
Score = 79.7 bits (195), Expect = 3e-14
Identities = 76/301 (25%), Positives = 107/301 (35%), Gaps = 70/301 (23%)
Query: 718 YCNATVKIPKCCKGFYGP-----------------DCNQCPGGFSNPCSGNGQCADSLGG 760
YC+ + P C G D N C G PC G C+++
Sbjct: 261 YCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYC--GTHQPCLNGGTCSNTGPD 318
Query: 761 NGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGT------C 814
C C EG+ G C+ C+ C+NR G+C + C
Sbjct: 319 KYQCSCPEGYSGPNCEIAEH------------ACLSDPCHNR----GSCKETSLGFECEC 362
Query: 815 RDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEG-----DGTLCSEMD 869
G G C C P C TC+ C+C + G D C E
Sbjct: 363 SPGWTGPTCSTNIDDCSP--NNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANEC-EAK 419
Query: 870 PCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCL 929
PC NA+ K ++ C C GW G D + IN+CL G C ++ASC
Sbjct: 420 PCV---------NAKSCKNLIASYYCDCLPGWMGQNCDIN-INDCL----GQCQNDASCR 465
Query: 930 YVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
+ G C C G+ G+ CE I C + C CQ+ + + C+C G+ G
Sbjct: 466 DLVNGY-RCICPPGYAGD--HCERDIDEC--ASNPCLNGGHCQNEINR-FQCLCPTGFSG 519
Query: 989 D 989
+
Sbjct: 520 N 520
Score = 78.6 bits (192), Expect = 7e-14
Identities = 66/271 (24%), Positives = 95/271 (35%), Gaps = 45/271 (16%)
Query: 1352 AQNVCFGNGICLDGVNGTGVCECGEGFSGTACE--------------------------T 1385
+ NVC +G C G C+C +GF+GT C
Sbjct: 595 SSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCI 654
Query: 1386 CTEGKYGIHCDQACS-CVHGRCNQGP-----LGDGSCDCDVGWRGVHCDNATTEDNCNGT 1439
C++G G +C+ + C C+ G + D CDC GW+G C + ++ + T
Sbjct: 655 CSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCD-EAT 713
Query: 1440 CHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCT 1499
C+ C D C C G++ GT C C C C
Sbjct: 714 CNNGGTCYDEGD-AFKCMCPGGWE--GTTCNIARNSSCLPNPCHNGGTCV-VNGESFTCV 769
Query: 1500 CKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVC 1559
CK G+ G I N C + C + C G N C C P + G IN+
Sbjct: 770 CKEGWEGP-ICAQNTNDCSPH--PCYNSGTCVD-GDNWYRCECAPGFAGPD---CRININ 822
Query: 1560 LTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
++ C+ A C R C C P + G
Sbjct: 823 ECQSSPCAFGATCVDEINGYR-CVCPPGHSG 852
Score = 75.1 bits (183), Expect = 8e-13
Identities = 59/187 (31%), Positives = 82/187 (43%), Gaps = 25/187 (13%)
Query: 1950 CCKGYFGRDCQACPGGPD-APCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G+ C + D A CNN G C D+ A +C C G+ GT C +
Sbjct: 693 CKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAF-KCMCPGGWEGTTCNIA----RNSS 747
Query: 2009 CLPCGCSDHGQCDDGITG-SGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENNT 2066
CLP C + G C + G S C+C+ GW GP C A C+P PC TC + +
Sbjct: 748 CLPNPCHNGGTC--VVNGESFTCVCKEGWEGPIC---AQNTNDCSPHPCYNSGTCVDGDN 802
Query: 2067 ---CECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCT 2122
CEC + G C + ++ C+ + CA A C + C C G+ G C
Sbjct: 803 WYRCECAPGFAGP--DCRININECQ--SSPCAFGATCVDEINGYRCVCPPGH--SGAKCQ 856
Query: 2123 EID--PC 2127
E+ PC
Sbjct: 857 EVSGRPC 863
Score = 73.2 bits (178), Expect = 3e-12
Identities = 85/325 (26%), Positives = 107/325 (32%), Gaps = 72/325 (22%)
Query: 1322 GCQPKCVRTVITRECCA-----GFFGPQCQPCPGNAQNVC-----------FGNGICLDG 1365
GC PK + +C G + +C P PG +C +G +C
Sbjct: 237 GCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKD 296
Query: 1366 VNGTGV-------------------CECGEGFSGTACETCTEGKYGIHCDQACSCVHGRC 1406
+N G C C EG+SG CE C G C
Sbjct: 297 LNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHN-----RGSC 351
Query: 1407 NQGPLGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSDGTASCKCAAGFQGN 1465
+ LG C+C GW G C +T D+C+ C C D KC Q
Sbjct: 352 KETSLG-FECECSPGWTGPTC--STNIDDCSPNNCSHGGTC---QDLVNGFKCVCPPQWT 405
Query: 1466 GTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCD 1525
G C ++A E C CK C C G+ G + IN CL G C
Sbjct: 406 GKTC-QLDANECEAKPCVNAKSCKNLI-ASYYCDCLPGWMGQN-CDININDCL---GQCQ 459
Query: 1526 KNAECTQTGPNQAACNCLPAYTGDG-----KVCTLINVCLTKNGG-----CSEFAICNHT 1575
+A C N C C P Y GD C N CL NGG + F T
Sbjct: 460 NDASCRDL-VNGYRCICPPGYAGDHCERDIDECA-SNPCL--NGGHCQNEINRFQCLCPT 515
Query: 1576 GQVERTCT-----CKPNYIGDGFTC 1595
G C C+PN +G C
Sbjct: 516 GFSGNLCQLDIDYCEPNPCQNGAQC 540
Score = 71.6 bits (174), Expect = 9e-12
Identities = 82/310 (26%), Positives = 110/310 (35%), Gaps = 65/310 (20%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
+C G+ G C + C + C D VNG C C G++G CE
Sbjct: 437 DCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYR-CICPPGYAGDHCER--------D 487
Query: 1395 CDQACS--CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLTNSD 1451
D+ S C++G Q + C C G+ G C D C C A C N
Sbjct: 488 IDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQ--LDIDYCEPNPCQNGAQCY-NRA 544
Query: 1452 GTASCKCAAGFQGNG----------TICTAINACE--------------ISNGGCSAKAD 1487
CKC ++G T C I++C IS+ C
Sbjct: 545 SDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGK 604
Query: 1488 CKRTTPGRRVCTCKAGYTG----DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCL 1543
CK + G+ C C G+TG + I E NPC N G C G N C C
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYCHENINDCESNPC-RNGGTC-------IDGVNSYKCICS 656
Query: 1544 PAYTGDGKVC-TLINVCLTK---NGG-----CSEFAICNHTGQVERTCTCKPNYIGDGFT 1594
+ +G C T IN C NGG ++F G +TC + + D T
Sbjct: 657 DGW--EGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQC-DEAT 713
Query: 1595 CR--GSIYQE 1602
C G+ Y E
Sbjct: 714 CNNGGTCYDE 723
Score = 67.8 bits (164), Expect = 1e-10
Identities = 64/269 (23%), Positives = 102/269 (37%), Gaps = 43/269 (15%)
Query: 728 CCKGFYGPDCN----QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNK 783
C G+ G C+ QC C+ G C D G C+C G++G+ C + +
Sbjct: 693 CKNGWKGKTCHSRDSQCDEA---TCNNGGTCYDE-GDAFKCMCPGGWEGTTCNIARNSSC 748
Query: 784 YGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
C+ CV +G T C++G G +C + T+ C P+ C+ TC
Sbjct: 749 LPNPCHNGGTCV---------VNGESFTCVCKEGWEGPICAQNTNDCSPHP--CYNSGTC 797
Query: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903
+ C C G+ G + ++ C C+ A C+ G + CVC G +G
Sbjct: 798 VDGDNWYRCECAPGFAGPDCRIN-INECQS---SPCAFGATCVDEING-YRCVCPPGHSG 852
Query: 904 ------NGRDCSEINNCLLPSAGGCHDNA----------SCLYVGPGQNECECKKGFR-- 945
+GR C + + ++P D+ +C V G C KG
Sbjct: 853 AKCQEVSGRPCITMGS-VIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSEC 911
Query: 946 GNGIDCEPITSCLEQTGKCHPLASCQSTS 974
+G C PI C + C+S+S
Sbjct: 912 PSGQSCIPILDDQCFVHPCTGVGECRSSS 940
Score = 66.6 bits (161), Expect = 3e-10
Identities = 67/245 (27%), Positives = 95/245 (38%), Gaps = 57/245 (23%)
Query: 101 CPGRW-GPDCIECPGGA--GSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
CPG W G C + +PC+ G+C E + TC C+EG+ G C +D
Sbjct: 731 CPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGE-SFTCVCKEGWEGPICAQNTND---- 785
Query: 158 PSCSSVCNCVHGVCNSG--LDGDG--TCECYSAYTGPKCDKPIPECAALLCPENSRCSPS 213
CS H NSG +DGD CEC + GP C I EC + C + C
Sbjct: 786 --CSP-----HPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATC--- 835
Query: 214 TEDENKLECKCLPNYRG-------------------DG-KYCDPINPCLRKICHPHAHCT 253
++ N C C P + G DG K+ D N C + + C+
Sbjct: 836 VDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTC--QCLNGRIACS 893
Query: 254 YLGPNRHSCTCQEGYR--GDGQVCLPV--DPCQIN----FGNCPTKS-----TVCKYDGP 300
+ C +G+ GQ C+P+ D C ++ G C + S T C D
Sbjct: 894 KVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSY 953
Query: 301 GQSHC 305
Q +C
Sbjct: 954 YQDNC 958
Score = 66.2 bits (160), Expect = 4e-10
Identities = 83/306 (27%), Positives = 116/306 (37%), Gaps = 53/306 (17%)
Query: 1901 ECGSCVNTPSCPRWSK-------PKGVKQKCLYN----LPFKRNLEGCRERCSLVIQIPR 1949
E CVN SC P + Q C N L +N CR+ + I
Sbjct: 417 EAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCI-- 474
Query: 1950 CCKGYFG----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C GY G RD C P C N G C ++ + +C C TGF+G C++
Sbjct: 475 CPPGYAGDHCERDIDECASNP---CLNGGHCQNEINRF-QCLCPTGFSGNLCQLDI---- 526
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVC-TPPCSAHATCKEN 2064
C P C + QC + C C + G +C + L C T PC +C
Sbjct: 527 -DYCEPNPCQNGAQCYNR-ASDYFCKCPEDYEGKNC---SHLKDHCRTTPCEVIDSC--- 578
Query: 2065 NTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEI 2124
T + +G+ + C +G C SQ G K +C C KG+ G + I
Sbjct: 579 -TVAMASNDTPEGVRYISSNVC-GPHGKCK-----SQSGGKFTCDCNKGFTGT-YCHENI 630
Query: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHAD 2184
+ C + C TC + G +KC C + +G CE I+ C Q+ CH
Sbjct: 631 NDCE---SNPCRNGGTC-IDGVNSYKCICSDGW--EGAYCETN---INDCSQN--PCHNG 679
Query: 2185 AKCVDL 2190
C DL
Sbjct: 680 GTCRDL 685
Score = 65.9 bits (159), Expect = 5e-10
Identities = 57/177 (32%), Positives = 71/177 (40%), Gaps = 40/177 (22%)
Query: 2017 HGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSA-HATCKENNTCECNLDYEG 2075
H CD +G C GW GP C+ A+C CS H +CK C C Y
Sbjct: 209 HYACDQ----NGNKTCMEGWMGPECNR-----AICRQGCSPKHGSCKLPGDCRCQ--YGW 257
Query: 2076 DGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG-----DGHSCTEIDPCADG 2130
G+ C D C + GC C++ C C+ + G D + C PC
Sbjct: 258 QGLYC---DKCIP-HPGCVH-GICNEPW---QCLCETNWGGQLCDKDLNYCGTHQPC--- 306
Query: 2131 LNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
LNGG TC TGP K++C C Y G NCE + CL D CH C
Sbjct: 307 LNGG-----TCSNTGPDKYQCSCPEGY--SGPNCE---IAEHACLSD--PCHNRGSC 351
Score = 50.4 bits (119), Expect = 2e-05
Identities = 47/167 (28%), Positives = 68/167 (40%), Gaps = 32/167 (19%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
+C GF GPDC N+C S+PC+ C D + G C+C G G++CQ S
Sbjct: 807 ECAPGFAGPDCRININECQ---SSPCAFGATCVDEINGY-RCVCPPGHSGAKCQEVS--- 859
Query: 783 KYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHAT 842
+ C+ + + D C T C +G C K CGP + C +H
Sbjct: 860 ------GRPCITMGSVIPDGAKWDDDCNTCQCLNGRIA--CSKVW--CGP--RPCLLHKG 907
Query: 843 CEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC-SRNAECIKT 888
SCI + + PCTG+ G C S + + +KT
Sbjct: 908 HSECPSGQSCIPILDDQ------CFVHPCTGV--GECRSSSLQPVKT 946
Score = 40.4 bits (93), Expect = 0.023
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 24/180 (13%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCR-HICRK--------DYLQPRCCPGR 104
C +G T + +G C+ +E + + C H C ++ + C PG
Sbjct: 753 CHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGF 812
Query: 105 WGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSV 163
GPDC I SPC +C + + G C C G G C+ + G C ++
Sbjct: 813 AGPDCRININECQSSPCAFGATCVDEINGY-RCVCPPGHSGAKCQ-----EVSGRPCITM 866
Query: 164 CNCV------HGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDE 217
+ + CN+ +G C + GP+ + CP C P +D+
Sbjct: 867 GSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPR--PCLLHKGHSECPSGQSCIPILDDQ 924
Score = 39.3 bits (90), Expect = 0.050
Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 32/180 (17%)
Query: 1335 ECCAGFFGPQCQPCPGNAQ-NVCFGNGICLDGVNGTGVCECGEGFSGTACETCT------ 1387
EC GF GP C+ Q + C C+D +NG C C G SG C+ +
Sbjct: 807 ECAPGFAGPDCRININECQSSPCAFGATCVDEINGYR-CVCPPGHSGAKCQEVSGRPCIT 865
Query: 1388 -------EGKYGIHCDQACSCVHGR--CNQ---GP----LGDGSCDCDVGWRGVHCDNAT 1431
K+ C+ C C++GR C++ GP L G +C G +
Sbjct: 866 MGSVIPDGAKWDDDCN-TCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCI----PI 920
Query: 1432 TEDNC-NGTCHTSANCLTNSDGTASCKCAAG--FQGNGTICTAINACEISNGGCSAKADC 1488
+D C C C ++S KC + +Q N T E+ + G + + C
Sbjct: 921 LDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHIC 980
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 103 bits (258), Expect = 2e-21
Identities = 105/398 (26%), Positives = 144/398 (36%), Gaps = 105/398 (26%)
Query: 1843 KCGAGRDIGDLFLNGQTCRIVQRELLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGEC 1902
+C GR + D G+ C R +D G GGRC G
Sbjct: 320 RCKDGRCVCDPGYTGEDCGT--RSCPWDCGE-------------GGRCVDGRCVCWPGYT 364
Query: 1903 GSCVNTPSCPRWSKPKGVKQ--KCLYNLPFK------RNLEG-CRERCSLVIQIPRCCKG 1953
G +T +CPR + +G + +C+ + + R+ G C +R C G
Sbjct: 365 GEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPG 424
Query: 1954 YFGRDC--QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE------------- 1998
Y G DC +ACP C RG C G C CN G++G C
Sbjct: 425 YTGTDCGSRACP----RDCRGRGRC-----ENGVCVCNAGYSGEDCGVRSCPGDCRGRGR 475
Query: 1999 ------MCWPGRFGPDC----LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLP 2048
MCWPG G DC P C G+C D G+C+C G+TG C ++
Sbjct: 476 CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVD-----GRCVCNPGFTGEDCGSRR--- 527
Query: 2049 AVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSC 2108
C C H C E+ C C+ Y G+ + + GGC +C C
Sbjct: 528 --CPGDCRGHGLC-EDGVCVCDAGYSGEDCS------TRSCPGGCRGRGQCLDG----RC 574
Query: 2109 SCQKGYKGDG-------HSCTEIDPCADGL----NGGCHEHA---TCKMTGPGKHKCE-- 2152
C+ GY G+ + C++ C DG+ G E TC G+ +CE
Sbjct: 575 VCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG 634
Query: 2153 ---CKSHYVGDGLNCEPEQLPID-----RCLQDNGQCH 2182
C Y G C P D RC+Q CH
Sbjct: 635 RCLCDPGYTGP--TCATRMCPADCRGRGRCVQGVCLCH 670
Score = 100 bits (249), Expect = 2e-20
Identities = 79/264 (29%), Positives = 103/264 (39%), Gaps = 67/264 (25%)
Query: 728 CCKGFYGPDCN--QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYG 785
C G+ G DC+ CPGG C G GQC D G C+CE+G+ G C PN
Sbjct: 545 CDAGYSGEDCSTRSCPGG----CRGRGQCLD-----GRCVCEDGYSGEDCGVRQCPND-- 593
Query: 786 PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEY 845
C++ HG C DG C+ C +G C +T CH CE
Sbjct: 594 --CSQ-----HGVC-----QDGVCI---CWEGYVSEDCSIRTCPSN-----CHGRGRCE- 632
Query: 846 SNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNG 905
C+C GY G C+ T + P C C++ C+C G+ G
Sbjct: 633 ---EGRCLCDPGY--TGPTCA-----TRMCPADCRGRGRCVQ-----GVCLCHVGY--GG 675
Query: 906 RDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCH 965
DC + GGC C +C C +GFRG DC I +C G C
Sbjct: 676 EDCGQEEPPASACPGGCGPRELC-----RAGQCVCVEGFRGP--DC-AIQTC---PGDCR 724
Query: 966 PLASCQSTSSGVWSCVCQEGYEGD 989
C SCVC++GY G+
Sbjct: 725 GRGECHD-----GSCVCKDGYAGE 743
Score = 99.0 bits (245), Expect = 5e-20
Identities = 85/314 (27%), Positives = 117/314 (37%), Gaps = 85/314 (27%)
Query: 1888 GRCDTFTTFDASGECGSCVNTPSCPRWSKPKG--VKQKCLYNLPF-------KRNLEGCR 1938
GRC++ G G T +CP + +G V +C+ N F +R CR
Sbjct: 474 GRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCR 533
Query: 1939 ERCSLVIQIPRCCKGYFGRDC--QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTA 1996
+ C GY G DC ++CPGG C RG CLD G C C G++G
Sbjct: 534 GHGLCEDGVCVCDAGYSGEDCSTRSCPGG----CRGRGQCLD-----GRCVCEDGYSGED 584
Query: 1997 CEM-------------------CWPGRFGPDC----LPCGCSDHGQCDDGITGSGQCLCE 2033
C + CW G DC P C G+C++G +CLC+
Sbjct: 585 CGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEG-----RCLCD 639
Query: 2034 TGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDN--- 2090
G+TGP+C T+ +C C C + C C++ Y G+ C Q+
Sbjct: 640 PGYTGPTCATR-----MCPADCRGRGRCVQ-GVCLCHVGYGGED--------CGQEEPPA 685
Query: 2091 ----GGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGP 2146
GGC C C C +G++G C I C G C C
Sbjct: 686 SACPGGCGPRELCRAG----QCVCVEGFRGP--DCA-IQTCP----GDCRGRGECH---- 730
Query: 2147 GKHKCECKSHYVGD 2160
C CK Y G+
Sbjct: 731 -DGSCVCKDGYAGE 743
Score = 89.4 bits (220), Expect = 4e-17
Identities = 88/314 (28%), Positives = 116/314 (36%), Gaps = 75/314 (23%)
Query: 1888 GRCDTFTTFDASGECGSCVNTPSCPRWSKPKG--VKQKCLYNLPF-------KRNLEGCR 1938
GRC F G G PSCP + +G V+ C+ F + GC
Sbjct: 200 GRCVCFP-----GYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCS 254
Query: 1939 ERCSLVIQIPRCCKGYFGRDC--QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTA 1996
+R C GY G DC ++CP G C+ RG C G C CN G+ G
Sbjct: 255 QRGRCEGGRCVCDPGYTGDDCGMRSCPRG----CSQRGRC-----ENGRCVCNPGYTGED 305
Query: 1997 CEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCS 2056
C G P GCS G+C DG +C+C+ G+TG C T++ C C
Sbjct: 306 C--------GVRSCPRGCSQRGRCKDG-----RCVCDPGYTGEDCGTRS-----CPWDCG 347
Query: 2057 AHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG 2116
C + C C Y G+ + C +D C RC C C GY G
Sbjct: 348 EGGRCVDGR-CVCWPGYTGEDCSTRT---CPRD---CRGRGRCEDG----ECICDTGYSG 396
Query: 2117 DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPID---- 2172
D D G C++ C+ +C C Y G +C P D
Sbjct: 397 D-------DCGVRSCPGDCNQRGRCE-----DGRCVCWPGYT--GTDCGSRACPRDCRGR 442
Query: 2173 -RCLQDNGQCHADA 2185
RC +NG C +A
Sbjct: 443 GRC--ENGVCVCNA 454
Score = 85.9 bits (211), Expect = 5e-16
Identities = 87/320 (27%), Positives = 113/320 (35%), Gaps = 71/320 (22%)
Query: 704 YSGRFGSLKSGCARYCNATVKIPK----CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADS 757
YSG ++S C CN + C G+ G DC CP C G G+C
Sbjct: 394 YSGDDCGVRS-CPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACP----RDCRGRGRCE-- 446
Query: 758 LGGNGTCICEEGFQGSQC--QFCSDPNKYGPRCNK-KCLCVHG---------TCNNRIDS 805
NG C+C G+ G C + C + RC +C+C G C
Sbjct: 447 ---NGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRG 503
Query: 806 DGACLTG--TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGT 863
G C+ G C G G C + C H CE C+C AGY G+
Sbjct: 504 RGRCVDGRCVCNPGFTGEDCGSRRCPGD-----CRGHGLCE----DGVCVCDAGYSGE-- 552
Query: 864 LCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNG---RDCSEINNCLLPSAG 920
D T PGGC +C+ CVC+ G++G R C N+C G
Sbjct: 553 -----DCSTRSCPGGCRGRGQCL-----DGRCVCEDGYSGEDCGVRQCP--NDC--SQHG 598
Query: 921 GCHDNASCLYVGPGQNECE---CKKGFRGNGIDCEPITSCLEQTGKCHPL-------ASC 970
C D + G +C C G G CE CL G P A C
Sbjct: 599 VCQDGVCICWEGYVSEDCSIRTCPSNCHGRG-RCEE-GRCLCDPGYTGPTCATRMCPADC 656
Query: 971 QSTSSGVWS-CVCQEGYEGD 989
+ V C+C GY G+
Sbjct: 657 RGRGRCVQGVCLCHVGYGGE 676
Score = 84.7 bits (208), Expect = 1e-15
Identities = 100/372 (26%), Positives = 130/372 (34%), Gaps = 99/372 (26%)
Query: 654 PPSIVPILPHRCDETKREMKLGTCV--------SCSLVYWSRCPANSEPTALFTHRCV-- 703
PPS P C++ R ++ G CV SC W CP + + RCV
Sbjct: 180 PPSASGSCPDDCNDQGRCVR-GRCVCFPGYTGPSCG---WPSCPGDCQGRG----RCVQG 231
Query: 704 -------YSGRFGSLKSGCARYCNATVKIPK----CCKGFYGPDCNQ--CPGGFSNPCSG 750
+SG S +S C R C+ + C G+ G DC CP G CS
Sbjct: 232 VCVCRAGFSGPDCSQRS-CPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG----CSQ 286
Query: 751 NGQCADSLGGNGTCICEEGFQGSQCQFCSDP---NKYGPRCNKKCLCVHG---------T 798
G+C NG C+C G+ G C S P ++ G + +C+C G +
Sbjct: 287 RGRCE-----NGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRS 341
Query: 799 CNNRIDSDGACLTG--TCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKA 856
C G C+ G C G G C +T + C CE CIC
Sbjct: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCP-----RDCRGRGRCE----DGECICDT 392
Query: 857 GYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLL 916
GY GD D PG C++ C CVC G+TG DC
Sbjct: 393 GYSGD-------DCGVRSCPGDCNQRGRC-----EDGRCVCWPGYTGT--DCGS-----R 433
Query: 917 PSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSG 976
C C C C G+ G DC + SC G C C+S
Sbjct: 434 ACPRDCRGRGRC-----ENGVCVCNAGYSGE--DC-GVRSC---PGDCRGRGRCES---- 478
Query: 977 VWSCVCQEGYEG 988
C+C GY G
Sbjct: 479 -GRCMCWPGYTG 489
Score = 77.4 bits (189), Expect = 2e-13
Identities = 84/281 (29%), Positives = 98/281 (34%), Gaps = 81/281 (28%)
Query: 100 CCPGRWGPDC--IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
C PG GP C CPG C GRG C +G+ C C+ GF G
Sbjct: 204 CFPGYTGPSCGWPSCPGD----CQGRGRCVQGV-----CVCRAGFS-------------G 241
Query: 158 PSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDE 217
P CS +C G G G C C YTG +C CP CS E
Sbjct: 242 PDCSQ-RSCPRGCSQRGRCEGGRCVCDPGYTG-------DDCGMRSCPRG--CSQRGRCE 291
Query: 218 NKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLP 277
N C C P Y G+ C + C R C C C C GY G+
Sbjct: 292 NG-RCVCNPGYTGED--CG-VRSCPRG-CSQRGRC-----KDGRCVCDPGYTGE------ 335
Query: 278 VDPCQINFGNCPTKSTVCKYD-GPG----QSHCECKEHYQNFVPGVGCSMTDICKSDNPC 332
+C T+S C +D G G C C Y G CS T C D C
Sbjct: 336 ---------DCGTRS--CPWDCGEGGRCVDGRCVCWPGY----TGEDCS-TRTCPRD--C 377
Query: 333 HRNANCTTVAPGRTECICQKGYVGDGL---TCYGNIMERLR 370
C ECIC GY GD +C G+ +R R
Sbjct: 378 RGRGRCED-----GECICDTGYSGDDCGVRSCPGDCNQRGR 413
Score = 77.0 bits (188), Expect = 2e-13
Identities = 75/290 (25%), Positives = 99/290 (34%), Gaps = 78/290 (26%)
Query: 728 CCKGFYGPDCNQCPGGF---SNPCSGNGQCADSLGG-----NGTCICEEGFQGSQCQFCS 779
C G+ GP C+ S+P S +G C D G C+C G+ G C + S
Sbjct: 158 CEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPS 217
Query: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI 839
P C + CV G C CR G +G C +++ G C
Sbjct: 218 CPGD----CQGRGRCVQGVC-------------VCRAGFSGPDCSQRSCPRG-----CSQ 255
Query: 840 HATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQ 899
CE C+C GY GD C M C P GCS+ C CVC
Sbjct: 256 RGRCE----GGRCVCDPGYTGDD--CG-MRSC----PRGCSQRGRC-----ENGRCVCNP 299
Query: 900 GWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGI-------DCE 952
G+T G DC + +C GC C C C G+ G DC
Sbjct: 300 GYT--GEDCG-VRSC----PRGCSQRGRC-----KDGRCVCDPGYTGEDCGTRSCPWDCG 347
Query: 953 PITSCLEQTGKCHPLASCQSTSSGV-------------WSCVCQEGYEGD 989
C++ C P + + S+ C+C GY GD
Sbjct: 348 EGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGD 397
Score = 75.1 bits (183), Expect = 8e-13
Identities = 87/332 (26%), Positives = 111/332 (33%), Gaps = 73/332 (21%)
Query: 1268 QKNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGN-EKRRCIYTSYFMGRRTLFIGCQPK 1326
Q+ RC++ G T CP + G E C+ + + G C
Sbjct: 410 QRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD 469
Query: 1327 CVRTVITRE----CCAGFFGPQC--QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSG 1380
C C G+ G C + CPG+ C G G C+DG C C GF+G
Sbjct: 470 CRGRGRCESGRCMCWPGYTGRDCGTRACPGD----CRGRGRCVDGR-----CVCNPGFTG 520
Query: 1381 TACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTC 1440
C + C C HG C DG C CD G+ G C +C G C
Sbjct: 521 EDCGSR-------RCPGDCRG-HGLCE-----DGVCVCDAGYSGEDCSTR----SCPGGC 563
Query: 1441 HTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTC 1500
CL DG C C G+ G + C CS C+ VC C
Sbjct: 564 RGRGQCL---DG--RCVCEDGYSGED---CGVRQCP---NDCSQHGVCQ-----DGVCIC 607
Query: 1501 KAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCL 1560
GY + I C N C C + C C P YTG C
Sbjct: 608 WEGYVSED---CSIRTCPSN---CHGRGRC-----EEGRCLCDPGYTGP--------TCA 648
Query: 1561 TKNGGCSEFAICNHTGQ-VERTCTCKPNYIGD 1591
T+ C A C G+ V+ C C Y G+
Sbjct: 649 TRM--CP--ADCRGRGRCVQGVCLCHVGYGGE 676
Score = 73.2 bits (178), Expect = 3e-12
Identities = 99/383 (25%), Positives = 131/383 (34%), Gaps = 122/383 (31%)
Query: 1288 SSELTCPFGTKSLGNEKR-RCI----YTSYFMGRRTLFIGCQPK--CVRTVITRECCAGF 1340
S+ +CP G R RC+ YT G + CQ + CV+ V C AGF
Sbjct: 182 SASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCV--CRAGF 239
Query: 1341 FGPQC--QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTAC--ETCTEGKYGIHCD 1396
GP C + CP C G C +G G C C G++G C +C G C
Sbjct: 240 SGPDCSQRSCPRG----CSQRGRC-EG----GRCVCDPGYTGDDCGMRSCPRG-----CS 285
Query: 1397 QACSCVHGRC---------------------NQGPLGDGSCDCDVGWRGVHCDNATTEDN 1435
Q C +GRC +G DG C CD G+ G C + +
Sbjct: 286 QRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWD 345
Query: 1436 C-------NGTC-----HTSANCLTNS------------DGTASCKCAAGFQGNGT---- 1467
C +G C +T +C T + DG C C G+ G+
Sbjct: 346 CGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDG--ECICDTGYSGDDCGVRS 403
Query: 1468 ---ICTAINACE---------ISNGGCSAKADCKRTTPGR-----RVCTCKAGYTGDGIV 1510
C CE + C ++A C R GR VC C AGY+G+
Sbjct: 404 CPGDCNQRGRCEDGRCVCWPGYTGTDCGSRA-CPRDCRGRGRCENGVCVCNAGYSGED-- 460
Query: 1511 CLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK--NGGCSE 1568
+ C G C C C C P YTG C T+ G C
Sbjct: 461 -CGVRSC---PGDCRGRGRC-----ESGRCMCWPGYTG--------RDCGTRACPGDCRG 503
Query: 1569 FAICNHTGQVERTCTCKPNYIGD 1591
C V+ C C P + G+
Sbjct: 504 RGRC-----VDGRCVCNPGFTGE 521
Score = 71.2 bits (173), Expect = 1e-11
Identities = 102/370 (27%), Positives = 132/370 (35%), Gaps = 86/370 (23%)
Query: 53 KCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPG-CRHICRKDYLQPRCCPGRWGPDC-- 109
+C +G + +G G DC S PG CR R + + C PG G DC
Sbjct: 444 RCENGVCVCNAGYSG-EDCGVR--------SCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
Query: 110 IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACET--CADDNLFGPSCSS-VCNC 166
CPG C GRG C +G C C GF G C + C D C VC C
Sbjct: 495 RACPGD----CRGRGRCVDGR-----CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVC 545
Query: 167 VHGV---------CNSGLDG-----DGTCECYSAYTGPKCDKPIPECAALLCPENSRCSP 212
G C G G DG C C Y+G +C CP + CS
Sbjct: 546 DAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSG-------EDCGVRQCPND--CSQ 596
Query: 213 STEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGD- 271
++ + C C Y + C I C CH C C C GY G
Sbjct: 597 HGVCQDGV-CICWEGYVSED--CS-IRTCPSN-CHGRGRC-----EEGRCLCDPGYTGPT 646
Query: 272 --GQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD 329
++C P D C+ G C +C + G G C +E + PG GC ++C++
Sbjct: 647 CATRMC-PAD-CR-GRGRCVQGVCLC-HVGYGGEDCGQEEPPASACPG-GCGPRELCRAG 701
Query: 330 ---------NPCHRNANCTTVAPGRTE-----CICQKGYVGDGL-----TCYGNIMERLR 370
P C GR E C+C+ GY G+ T G M L
Sbjct: 702 QCVCVEGFRGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLE 761
Query: 371 ELNTEPRGKW 380
E T R +W
Sbjct: 762 E--TTVRTEW 769
Score = 68.9 bits (167), Expect = 6e-11
Identities = 84/299 (28%), Positives = 103/299 (34%), Gaps = 84/299 (28%)
Query: 100 CCPGRWGPDC--IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC--ETCADDNL 155
C PG G DC CP G C+ RG C NG C C G+ G C +C
Sbjct: 266 CDPGYTGDDCGMRSCPRG----CSQRGRCE-----NGRCVCNPGYTGEDCGVRSCP---- 312
Query: 156 FGPSCSSVCNCVHG--VCNSGLDG-------------------DGTCECYSAYTGPKCDK 194
CS C G VC+ G G DG C C+ YTG
Sbjct: 313 --RGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTG----- 365
Query: 195 PIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDG-------KYCDPINPCL--RKI 245
+C+ CP + R ED EC C Y GD C+ C R +
Sbjct: 366 --EDCSTRTCPRDCRGRGRCEDG---ECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCV 420
Query: 246 CHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFG--NCPTKSTVCKYDGPGQS 303
C P Y G + S C RG G+ V C + +C +S C D G+
Sbjct: 421 CWP----GYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRS--CPGDCRGRG 474
Query: 304 HCE-----CKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGD 357
CE C Y G C T C D C C GR C+C G+ G+
Sbjct: 475 RCESGRCMCWPGY----TGRDCG-TRACPGD--CRGRGRC---VDGR--CVCNPGFTGE 521
Score = 68.6 bits (166), Expect = 8e-11
Identities = 76/277 (27%), Positives = 95/277 (34%), Gaps = 103/277 (37%)
Query: 1324 QPKCVRTVITRECCAGFFGPQC--QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
Q +CVR C G+ GP C CPG+ C G G C+ GV C C GFSG
Sbjct: 194 QGRCVRGRCV--CFPGYTGPSCGWPSCPGD----CQGRGRCVQGV-----CVCRAGFSGP 242
Query: 1382 ACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCH 1441
C + C + CS GRC G C CD G+ G D+C
Sbjct: 243 DCSQRS-------CPRGCS-QRGRCE-----GGRCVCDPGYTG---------DDC----- 275
Query: 1442 TSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCK 1501
G SC GCS + C+ GR C C
Sbjct: 276 ----------GMRSCP----------------------RGCSQRGRCEN---GR--CVCN 298
Query: 1502 AGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLT 1561
GYTG+ + C GC + C C C P YTG+ C T
Sbjct: 299 PGYTGEDC---GVRSCPR---GCSQRGRC-----KDGRCVCDPGYTGED--------CGT 339
Query: 1562 KN--GGCSEFAICNHTGQVERTCTCKPNYIGDGFTCR 1596
++ C E C V+ C C P Y G+ + R
Sbjct: 340 RSCPWDCGEGGRC-----VDGRCVCWPGYTGEDCSTR 371
Score = 66.6 bits (161), Expect = 3e-10
Identities = 86/323 (26%), Positives = 110/323 (34%), Gaps = 83/323 (25%)
Query: 1269 KNRCDNNDTTIIRGRCRTCSSELTCPFGTKSLGN-EKRRCIYTSYFMGRRTLFIGCQPKC 1327
+ RC+N G +CP + G E RC+ + GR C C
Sbjct: 442 RGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 1328 V---RTVITRECC-AGFFGPQC--QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGT 1381
R V R C GF G C + CPG+ C G+G+C DGV C C G+SG
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGD----CRGHGLCEDGV-----CVCDAGYSGE 552
Query: 1382 ACET--CTEGKYGI-HC-DQACSCVHGR-------------CNQ-GPLGDGSCDCDVGWR 1423
C T C G G C D C C G C+Q G DG C C G+
Sbjct: 553 DCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYV 612
Query: 1424 GVHCDNATTEDNCNGTCHTS-ANCLTNSDGT----ASCKCAAGFQGNGTICTAINACEIS 1478
C T NC+G CL + T A+ C A +G G + C +
Sbjct: 613 SEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVG 672
Query: 1479 NGG----------------CSAKADCK-----------------RTTPGR---------R 1496
GG C + C+ +T PG
Sbjct: 673 YGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECHDG 732
Query: 1497 VCTCKAGYTGDGIVCLEINPCLE 1519
C CK GY G+ C E P +E
Sbjct: 733 SCVCKDGYAGED--CGEEVPTIE 753
Score = 65.1 bits (157), Expect = 9e-10
Identities = 83/319 (26%), Positives = 105/319 (32%), Gaps = 95/319 (29%)
Query: 100 CCPGRWGPDCIE--CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
C PG G DC CP C GRG C +G C C G+ G C
Sbjct: 359 CWPGYTGEDCSTRTCP----RDCRGRGRCEDG-----ECICDTGYSGDDCGV-------- 401
Query: 158 PSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKC-DKPIP------------------- 197
SC CN G C DG C C+ YTG C + P
Sbjct: 402 RSCPGDCN-QRGRCE-----DGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAG 455
Query: 198 ----ECAALLCPENSRCSPSTEDENKLECKCLPNY--------------RGDGKYCDPIN 239
+C CP + R E C C P Y RG G+ D
Sbjct: 456 YSGEDCGVRSCPGDCRGRGRCESG---RCMCWPGYTGRDCGTRACPGDCRGRGRCVDG-- 510
Query: 240 PCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFG--NCPTKSTVCKY 297
R +C+P + G + S C RG G V C + +C T+S
Sbjct: 511 ---RCVCNP----GFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGC 563
Query: 298 DGPGQ---SHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
G GQ C C++ Y G C + + N C ++ C CIC +GY
Sbjct: 564 RGRGQCLDGRCVCEDGYS----GEDCG---VRQCPNDCSQHGVCQDGV-----CICWEGY 611
Query: 355 VGDGL---TCYGNIMERLR 370
V + TC N R R
Sbjct: 612 VSEDCSIRTCPSNCHGRGR 630
Score = 55.5 bits (132), Expect = 7e-07
Identities = 36/112 (32%), Positives = 44/112 (39%), Gaps = 29/112 (25%)
Query: 1937 CRERCSLVIQIPRCCKGYFGRDC-------QACPGGPDAPCNNRGVCLDQYSATGECKCN 1989
CR R V + C GY G DC ACPGG C R +C G+C C
Sbjct: 656 CRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGG----CGPRELC-----RAGQCVCV 706
Query: 1990 TGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSC 2041
GF G C + P C G+C DG C+C+ G+ G C
Sbjct: 707 EGFRGPDCAI--------QTCPGDCRGRGECHDG-----SCVCKDGYAGEDC 745
Score = 52.4 bits (124), Expect = 6e-06
Identities = 48/189 (25%), Positives = 68/189 (35%), Gaps = 51/189 (26%)
Query: 1415 SCDCDVGWRGVHCDNATTED-----------NCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
+C C+ GW G C + T + +C C+ C+ C C G+
Sbjct: 155 TCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCV-----RGRCVCFPGYT 209
Query: 1464 GNGTICTAINACEISNGGCSAKADCK-RTTPGRRVCTCKAGYTGDGIVCLEINPCLENHG 1522
G S G S DC+ R + VC C+AG++G C + C
Sbjct: 210 GP------------SCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPD--CSQ-RSCPR--- 251
Query: 1523 GCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTC 1582
GC + C C C P YTGD C + + GCS+ C + C
Sbjct: 252 GCSQRGRC-----EGGRCVCDPGYTGDD--CGMRSC----PRGCSQRGRCEN-----GRC 295
Query: 1583 TCKPNYIGD 1591
C P Y G+
Sbjct: 296 VCNPGYTGE 304
Score = 49.7 bits (117), Expect = 4e-05
Identities = 55/208 (26%), Positives = 71/208 (34%), Gaps = 56/208 (26%)
Query: 2014 CSDHGQCDDGITGSGQCLCETGWTGPSCD--TQAVLPAVCTPPCSAHA--TCKENNTC-- 2067
CS HG D C CE GW GP+C T A +P P S C + C
Sbjct: 143 CSLHGVFD---LSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR 199
Query: 2068 -----------------ECNLDYEGDGITCTVVDFCKQDNGG--CAKVA---RCSQKGTK 2105
C D +G G V C+ G C++ + CSQ+G
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRC 259
Query: 2106 VS--CSCQKGYKGDG---HSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
C C GY GD SC GC + C+ +C C Y G+
Sbjct: 260 EGGRCVCDPGYTGDDCGMRSCPR----------GCSQRGRCE-----NGRCVCNPGYTGE 304
Query: 2161 GLNCEPEQLPIDRCLQDNGQCHADAKCV 2188
+C P R G+C D +CV
Sbjct: 305 --DCGVRSCP--RGCSQRGRC-KDGRCV 327
Score = 47.8 bits (112), Expect = 1e-04
Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 11/50 (22%)
Query: 728 CCKGFYGPDC--NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQC 775
C +GF GPDC CPG C G G+C D G+C+C++G+ G C
Sbjct: 705 CVEGFRGPDCAIQTCPGD----CRGRGECHD-----GSCVCKDGYAGEDC 745
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 102 bits (253), Expect = 6e-21
Identities = 95/364 (26%), Positives = 137/364 (37%), Gaps = 40/364 (10%)
Query: 12 GLVVQNFCSPAETTGQARRCDRKSLLTIRTECRSCALNLGVKCPD---GYTMITSGSVGV 68
G+ N P E TGQ D + C++ G C + GY +
Sbjct: 275 GVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQN-----GGTCHNTHGGYNCVCVNGWTG 329
Query: 69 RDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSC-A 127
DC + + G R C GR G C +PCN +C
Sbjct: 330 EDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDT 389
Query: 128 EGMEGNGTCSCQEGFGGTACETCADDNLFGPS-CSSVCNCVHGVCNSGLDGDGTCECYSA 186
+ G C+C G+ G AC D+ G + C C++ + G C+C
Sbjct: 390 NPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL------GSFECQCLQG 443
Query: 187 YTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINPCLRKI 245
YTGP+C+ + EC + C ++ C + + +C C+P Y +G +C+ + C
Sbjct: 444 YTGPRCEIDVNECVSNPCQNDATC---LDQIGEFQCICMPGY--EGVHCEVNTDECASSP 498
Query: 246 CHPHAHCTYLGPNRHSCTCQEGYRGDGQVC-LPVDPCQINFGNCPTKSTVCKYDGPGQSH 304
C + C N C C G+ G +C VD C + P K+ DGP
Sbjct: 499 CLHNGRCLD-KINEFQCECPTGF--TGHLCQYDVDEC----ASTPCKNGAKCLDGPNTYT 551
Query: 305 CECKEHYQNFVPGVGCSM-TDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYG 363
C C E Y G C + D C D PCH + VA C+C+ GY G C
Sbjct: 552 CVCTEGY----TGTHCEVDIDECDPD-PCHYGSCKDGVA--TFTCLCRPGYTGH--HCET 602
Query: 364 NIME 367
NI E
Sbjct: 603 NINE 606
Score = 99.4 bits (246), Expect = 4e-20
Identities = 92/336 (27%), Positives = 124/336 (36%), Gaps = 52/336 (15%)
Query: 99 RCCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
RC PG G C + A +PC G C E + C C F G C ++ P
Sbjct: 128 RCPPGWSGKSCQQADPCASNPCANGGQCLP-FEASYICHCPPSFHGPTCRQDVNECGQKP 186
Query: 159 SCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
C HG G C C + +TGP C++P C+ C C P+ + +
Sbjct: 187 GL-----CRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTH 241
Query: 219 KLECKCLPNYRGDGKYCDP-INPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCL- 276
EC CLP + G C+ I+ C C C G N ++C C + GQ C
Sbjct: 242 --ECACLPGFTGQN--CEENIDDCPGNNCKNGGACVD-GVNTYNCRCPPEW--TGQYCTE 294
Query: 277 PVDPCQI------NFGNCPTK----STVCKYDGPGQSHCE---------------CKEHY 311
VD CQ+ N G C + VC G+ E C +
Sbjct: 295 DVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRV 354
Query: 312 QNFV-------PGVGCSMTDICKSDNPCHRNANC-TTVAPGRTECICQKGYVGDGLTCYG 363
+F G+ C + D C S NPC+ +NC T G+ C C GY G C
Sbjct: 355 ASFYCECPHGRTGLLCHLNDACIS-NPCNEGSNCDTNPVNGKAICTCPSGYTGP--ACSQ 411
Query: 364 NIMERLRELN-TEPRGKWQGRLTSFISLLDKAYAWP 398
++ E N E GK L SF + Y P
Sbjct: 412 DVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGP 447
Score = 98.6 bits (244), Expect = 7e-20
Identities = 87/278 (31%), Positives = 116/278 (41%), Gaps = 36/278 (12%)
Query: 727 KCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP 786
+C G+ G C Q SNPC+ GQC + C C F G C+ D N+ G
Sbjct: 128 RCPPGWSGKSCQQADPCASNPCANGGQCL-PFEASYICHCPPSFHGPTCR--QDVNECG- 183
Query: 787 RCNKKCLCVH-GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEY 845
K LC H GTC+N + S CR G C++ C P C TC
Sbjct: 184 --QKPGLCRHGGTCHNEVGS----YRCVCRATHTGPNCERPYVPCSP--SPCQNGGTCRP 235
Query: 846 SNG-TASCICKAGYEGDGTLCSE-MDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903
+ T C C G+ G C E +D C G C C+ G T+ C C WT
Sbjct: 236 TGDVTHECACLPGFTGQN--CEENIDDCPG---NNCKNGGACV-DGVNTYNCRCPPEWT- 288
Query: 904 NGRDCSE-INNC-LLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDC-EPITSCLEQ 960
G+ C+E ++ C L+P+A C + +C G N C C G+ G DC E I C
Sbjct: 289 -GQYCTEDVDECQLMPNA--CQNGGTCHNTHGGYN-CVCVNGWTGE--DCSENIDDC--A 340
Query: 961 TGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCYGNAA 998
+ C A+C + + C C G G LC+ N A
Sbjct: 341 SAACFHGATCHDRVASFY-CECPHG--RTGLLCHLNDA 375
Score = 95.9 bits (237), Expect = 5e-19
Identities = 75/295 (25%), Positives = 105/295 (35%), Gaps = 45/295 (15%)
Query: 728 CCKGFYGPDCNQCPGGFSNPCSGNGQC--ADSLG-GNGTCICEEGFQGSQC------QFC 778
C F GP C S PC G C D G + C C GF G C
Sbjct: 48 CGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACL 107
Query: 779 SDPNKYGPRCNK------KCLCVHGTCNNRIDSDGACLTGTCRDGSA------------- 819
++P + G C+ KC C G C + C +G
Sbjct: 108 TNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCP 167
Query: 820 ----GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLT 875
G C + + CG C TC G+ C+C+A + G C P +
Sbjct: 168 PSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPN--CER--PYVPCS 223
Query: 876 PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSE-INNCLLPSAGGCHDNASCLYVGPG 934
P C C TG TH C C G+T G++C E I++C C + +C+ G
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFT--GQNCEENIDDC---PGNNCKNGGACV-DGVN 277
Query: 935 QNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
C C + G E + C C +C +T G ++CVC G+ G+
Sbjct: 278 TYNCRCPPEWTGQ-YCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGE 330
Score = 94.4 bits (233), Expect = 1e-18
Identities = 84/299 (28%), Positives = 121/299 (40%), Gaps = 68/299 (22%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPN 782
+C +G+ GP C N+C SNPC + C D +G CIC G++G C+ +D
Sbjct: 439 QCLQGYTGPRCEIDVNEC---VSNPCQNDATCLDQIG-EFQCICMPGYEGVHCEVNTDEC 494
Query: 783 KYGPRCNKKCLCVH-GTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHA 841
P C+H G C ++I+ C G G LC C C A
Sbjct: 495 ASSP-------CLHNGRCLDKINE----FQCECPTGFTGHLCQYDVDECASTP--CKNGA 541
Query: 842 TCEYSNGTASCICKAGYEGDGTLCS-EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQG 900
C T +C+C GY G T C ++D C P C + K G T TC+C+ G
Sbjct: 542 KCLDGPNTYTCVCTEGYTG--THCEVDIDECD---PDPCHYGS--CKDGVATFTCLCRPG 594
Query: 901 WTG----------------NGRDCSEINN-----CLLPSAG-GCH-----------DNAS 927
+TG +G C + +N CL + G C D+ +
Sbjct: 595 YTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGT 654
Query: 928 CLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY 986
CL G EC C+ G+ G+ + I C CH +C+ +G ++C C EGY
Sbjct: 655 CLDKIDGY-ECACEPGYTGSMCNIN-IDEC--AGNPCHNGGTCEDGING-FTCRCPEGY 708
Score = 91.7 bits (226), Expect = 9e-18
Identities = 97/350 (27%), Positives = 130/350 (37%), Gaps = 79/350 (22%)
Query: 42 ECRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRH-ICRKDYLQPRC 100
+CR + G C DG + DC LPG R C +D +
Sbjct: 910 DCRPNPCHNGGSCTDGI------NTAFCDC------------LPGFRGTFCEEDINECAS 951
Query: 101 CPGRWGPDCIEC---------------------PGGAGSPCNGRGSCAEGMEGNGTCSCQ 139
P R G +C +C P S C G+C +G+ + TC C
Sbjct: 952 DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGIN-SFTCLCP 1010
Query: 140 EGFGGTACETCADDNLFGPSCSSVCNCVHG-VCNSGLDGDGTCECYSAYTGPKCDKPIPE 198
GF G+ C+ ++ C S C+HG C G G C C YTGP C +
Sbjct: 1011 PGFTGSYCQHDVNE------CDSQ-PCLHGGTCQDGC-GSYRCTCPQGYTGPNCQNLVHW 1062
Query: 199 CAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINPC----------LRKICH 247
C + C +C + + C+C + G YCD P C + ++C
Sbjct: 1063 CDSSPCKNGGKC---WQTHTQYRCECPSGW--TGLYCDVPSVSCEVAAQRQGVDVARLCQ 1117
Query: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCEC 307
C G N H C CQ GY G L VD C + C +T Y G G S C+C
Sbjct: 1118 HGGLCVDAG-NTHHCRCQAGYTGSYCEDL-VDECSPS--PCQNGATCTDYLG-GYS-CKC 1171
Query: 308 KEHYQNFVPGVGCS-MTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
Y GV CS D C S +PC C + P +C C +G G
Sbjct: 1172 VAGYH----GVNCSEEIDECLS-HPCQNGGTCLDL-PNTYKCSCPRGTQG 1215
Score = 91.3 bits (225), Expect = 1e-17
Identities = 80/262 (30%), Positives = 104/262 (39%), Gaps = 33/262 (12%)
Query: 1336 CCAGFFGPQCQ----PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKY 1391
C G+ G C C GN C G C DG+NG C C EG+ C +
Sbjct: 666 CEPGYTGSMCNINIDECAGNP---CHNGGTCEDGINGF-TCRCPEGYHDPTCLSEVN--- 718
Query: 1392 GIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSD 1451
C+ CVHG C L CDCD GW G +CD E N C C +
Sbjct: 719 --ECNSN-PCVHGACRDS-LNGYKCDCDPGWSGTNCDINNNECESN-PCVNGGTCKDMTS 773
Query: 1452 GTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVC 1511
G C C GF G T IN C ++ C + C G + C C YT G C
Sbjct: 774 GYV-CTCREGFSG-PNCQTNINEC--ASNPCLNQGTCIDDVAGYK-CNCLLPYT--GATC 826
Query: 1512 -LEINPCLENHGGCDKNAECTQTGPNQA-ACNCLPAYTGDGKVCTL-INVCLTKNGGCSE 1568
+ + PC + C EC Q+ ++ +C C + G+ C + IN C+ C
Sbjct: 827 EVVLAPCAPS--PCRNGGECRQSEDYESFSCVCPTGW--QGQTCEVDINECVL--SPCRH 880
Query: 1569 FAICNHTGQVERTCTCKPNYIG 1590
A C +T R C C+ Y G
Sbjct: 881 GASCQNTHGGYR-CHCQAGYSG 901
Score = 91.3 bits (225), Expect = 1e-17
Identities = 75/276 (27%), Positives = 105/276 (38%), Gaps = 46/276 (16%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNK 783
C GF G C N+C S+PC C D + TC C GF G C+
Sbjct: 933 CLPGFRGTFCEEDINECA---SDPCRNGANCTDCVDSY-TCTCPAGFSGIHCE------N 982
Query: 784 YGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
P C + GTC + I+S T C G G C + C Q C TC
Sbjct: 983 NTPDCTESSCFNGGTCVDGINS----FTCLCPPGFTGSYCQHDVNECDS--QPCLHGGTC 1036
Query: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG 903
+ G+ C C GY G C + +P C +C +T T + C C GWTG
Sbjct: 1037 QDGCGSYRCTCPQGYTGPN--CQNLVHWCDSSP--CKNGGKCWQTHT-QYRCECPSGWTG 1091
Query: 904 NGRDCSEINNCLLPSAGG------CHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSC 957
D ++ + G C C+ G + C C+ G+ G + C
Sbjct: 1092 LYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAG-NTHHCRCQAGYTG--------SYC 1142
Query: 958 LEQTGKCHPLASCQSTSS-----GVWSCVCQEGYEG 988
+ +C P + CQ+ ++ G +SC C GY G
Sbjct: 1143 EDLVDECSP-SPCQNGATCTDYLGGYSCKCVAGYHG 1177
Score = 90.9 bits (224), Expect = 1e-17
Identities = 104/420 (24%), Positives = 146/420 (34%), Gaps = 106/420 (25%)
Query: 1856 NGQTCRIVQRELLFDLGVAYGID-------------CLLIDPTLGGRCDTFTTFDASGEC 1902
N TC +V R + D + + CL GG CD T + C
Sbjct: 70 NAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRC 129
Query: 1903 GSCVNTPSC----PRWSKPKGVKQKCLYNLPFKRNL----------EGCRERCSLVIQIP 1948
+ SC P S P +CL PF+ + CR+ + Q P
Sbjct: 130 PPGWSGKSCQQADPCASNPCANGGQCL---PFEASYICHCPPSFHGPTCRQDVNECGQKP 186
Query: 1949 RCCK---------GYFGRDCQACPGGPD----------APCNNRGVCLDQYSATGECKCN 1989
C+ G + C+A GP+ +PC N G C T EC C
Sbjct: 187 GLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL 246
Query: 1990 TGFNGTACE--------------------------MCWPGRFGPDC---------LPCGC 2014
GF G CE C P G C +P C
Sbjct: 247 PGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 2015 SDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT---CECNL 2071
+ G C + G C+C GWTG C + + C ATC + CEC
Sbjct: 307 QNGGTCHN-THGGYNCVCVNGWTGEDCSEN--IDDCASAACFHGATCHDRVASFYCEC-- 361
Query: 2072 DYEGDGITCTVVDFCKQDNGGCAKVARCSQK--GTKVSCSCQKGYKGDGHSCTEIDPCAD 2129
+ G+ C + D C + C + + C K C+C GY G S ++D C+
Sbjct: 362 PHGRTGLLCHLNDAC--ISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS-QDVDECSL 418
Query: 2130 GLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
G N C EHA + G +C+C Y G CE + ++ C+ + C DA C+D
Sbjct: 419 GAN-PC-EHAGKCINTLGSFECQCLQGYTGP--RCE---IDVNECV--SNPCQNDATCLD 469
Score = 89.0 bits (219), Expect = 6e-17
Identities = 95/351 (27%), Positives = 124/351 (35%), Gaps = 119/351 (33%)
Query: 100 CCPGRWGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
C PG G C I AG+PC+ G+C +G+ G TC C EG+ C + ++ P
Sbjct: 666 CEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGF-TCRCPEGYHDPTCLSEVNECNSNP 724
Query: 159 SCSSVCNCVHGVCNSGLDG----------------------------DGTCE-------- 182
CVHG C L+G GTC+
Sbjct: 725 -------CVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVC 777
Query: 183 -CYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG----------- 230
C ++GP C I ECA+ C C +D +C CL Y G
Sbjct: 778 TCREGFSGPNCQTNINECASNPCLNQGTC---IDDVAGYKCNCLLPYTGATCEVVLAPCA 834
Query: 231 ---------------------------DGKYCD-PINPCLRKICHPHAHC--TYLGPNRH 260
G+ C+ IN C+ C A C T+ G +
Sbjct: 835 PSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGG---Y 891
Query: 261 SCTCQEGYRG-----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFV 315
C CQ GY G D C P +PC N G+C DG + C+C ++
Sbjct: 892 RCHCQAGYSGRNCETDIDDCRP-NPCH-NGGSCT--------DGINTAFCDCLPGFR--- 938
Query: 316 PGVGCSMTDI--CKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGN 364
G C DI C SD PC ANCT T C C G+ G+ C N
Sbjct: 939 -GTFCE-EDINECASD-PCRNGANCTDCVDSYT-CTCPAGF--SGIHCENN 983
Score = 89.0 bits (219), Expect = 6e-17
Identities = 82/313 (26%), Positives = 122/313 (38%), Gaps = 51/313 (16%)
Query: 685 WSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYGPDC----NQC 740
WS + ++ CV G + SG + C +GF GP+C N+C
Sbjct: 745 WSGTNCDINNNECESNPCVNGGTCKDMTSGY---------VCTCREGFSGPNCQTNINEC 795
Query: 741 PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCN 800
SNPC G C D + G C C + G+ C+ P C C
Sbjct: 796 A---SNPCLNQGTCIDDVAGY-KCNCLLPYTGATCEVVLAP------------CAPSPCR 839
Query: 801 N----RIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKA 856
N R D + C G G+ C+ + C + C A+C+ ++G C C+A
Sbjct: 840 NGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--VLSPCRHGASCQNTHGGYRCHCQA 897
Query: 857 GYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLL 916
GY G +++D C P C C G T C C G+ G + +IN C
Sbjct: 898 GYSGRNCE-TDIDDC---RPNPCHNGGSC-TDGINTAFCDCLPGFRGTFCE-EDINEC-- 949
Query: 917 PSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPIT-SCLEQTGKCHPLASCQSTSS 975
++ C + A+C C C GF +GI CE T C E + C +C +
Sbjct: 950 -ASDPCRNGANCTDCVDSYT-CTCPAGF--SGIHCENNTPDCTESS--CFNGGTCVDGIN 1003
Query: 976 GVWSCVCQEGYEG 988
++C+C G+ G
Sbjct: 1004 S-FTCLCPPGFTG 1015
Score = 87.8 bits (216), Expect = 1e-16
Identities = 83/299 (27%), Positives = 116/299 (38%), Gaps = 64/299 (21%)
Query: 1336 CCAGFFGPQCQ----PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKY 1391
C A GP C+ PC + + C G C + T C C GF+G CE +
Sbjct: 206 CRATHTGPNCERPYVPC---SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCP 262
Query: 1392 GIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTE-----DNC--NGTCH--- 1441
G +C +CV G + +C C W G +C E + C GTCH
Sbjct: 263 GNNCKNGGACVDG------VNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTH 316
Query: 1442 -----------TSANCLTNSDGTASCKCAAG---------------FQGNGTICTAINAC 1475
T +C N D AS C G G +C +AC
Sbjct: 317 GGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDAC 376
Query: 1476 EISNGGCSAKADCKRTTP--GRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQT 1533
ISN C+ ++C T P G+ +CTC +GYTG +++ C C+ +C T
Sbjct: 377 -ISN-PCNEGSNCD-TNPVNGKAICTCPSGYTGPA-CSQDVDECSLGANPCEHAGKCINT 432
Query: 1534 GPNQAACNCLPAYTGDGKVCTL-INVCLTKNGGCSEFAIC-NHTGQVERTCTCKPNYIG 1590
C CL YTG C + +N C+ + C A C + G+ + C C P Y G
Sbjct: 433 -LGSFECQCLQGYTGPR--CEIDVNECV--SNPCQNDATCLDQIGEFQ--CICMPGYEG 484
Score = 87.8 bits (216), Expect = 1e-16
Identities = 76/257 (29%), Positives = 107/257 (41%), Gaps = 42/257 (16%)
Query: 1950 CCKGYFGRDCQA-CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G C+ P ++ C N G C+D ++ C C GF G+ C+ +
Sbjct: 971 CPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF-TCLCPPGFTGSYCQ-----HDVNE 1024
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT-- 2066
C C G C DG GS +C C G+TGP+C Q ++ + PC C + +T
Sbjct: 1025 CDSQPCLHGGTCQDGC-GSYRCTCPQGYTGPNC--QNLVHWCDSSPCKNGGKCWQTHTQY 1081
Query: 2067 -CECNLDYEG-----DGITCTV------VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY 2114
CEC + G ++C V VD + C C G C CQ GY
Sbjct: 1082 RCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARL----CQHGGLCVDAGNTHHCRCQAGY 1137
Query: 2115 KGDGHSCTE-IDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDR 2173
G C + +D C+ C ATC G + C+C + Y G+NC E ID
Sbjct: 1138 TGS--YCEDLVDECSP---SPCQNGATC-TDYLGGYSCKCVAGY--HGVNCSEE---IDE 1186
Query: 2174 CLQDNGQCHADAKCVDL 2190
CL + C C+DL
Sbjct: 1187 CL--SHPCQNGGTCLDL 1201
Score = 87.4 bits (215), Expect = 2e-16
Identities = 88/327 (26%), Positives = 118/327 (36%), Gaps = 82/327 (25%)
Query: 728 CCKGFYGPDCN-QCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQF--------- 777
C KG GP+C S+PC +G C D + G C CE G+ GS C
Sbjct: 629 CLKGTTGPNCEINLDDCASSPCD-SGTCLDKIDGY-ECACEPGYTGSMCNINIDECAGNP 686
Query: 778 ------CSDP-NKYGPRC-----NKKCL----------CVHGTC---------------- 799
C D N + RC + CL CVHG C
Sbjct: 687 CHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWS 746
Query: 800 -------NNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQF---------CHIHATC 843
NN +S+ GTC+D ++G +C + GP Q C TC
Sbjct: 747 GTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTC 806
Query: 844 EYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKT-GTGTHTCVCQQGWT 902
C C Y G T + PC P C EC ++ + +CVC GW
Sbjct: 807 IDDVAGYKCNCLLPYTG-ATCEVVLAPC---APSPCRNGGECRQSEDYESFSCVCPTGW- 861
Query: 903 GNGRDCS-EINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQT 961
G+ C +IN C+L C ASC G C C+ G+ G + + I C +
Sbjct: 862 -QGQTCEVDINECVL---SPCRHGASCQNTHGGY-RCHCQAGYSGRNCETD-IDDC--RP 913
Query: 962 GKCHPLASCQSTSSGVWSCVCQEGYEG 988
CH SC + + C C G+ G
Sbjct: 914 NPCHNGGSCTDGINTAF-CDCLPGFRG 939
Score = 87.4 bits (215), Expect = 2e-16
Identities = 89/324 (27%), Positives = 127/324 (39%), Gaps = 65/324 (20%)
Query: 1333 TRECCAGFFGPQCQP-CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE------- 1384
T C AGF G C+ P ++ CF G C+DG+N C C GF+G+ C+
Sbjct: 968 TCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSF-TCLCPPGFTGSYCQHDVNECD 1026
Query: 1385 --------TCTEG--KYGIHCDQA-----CSCVHGRCNQGPLGDGS----------CDCD 1419
TC +G Y C Q C + C+ P +G C+C
Sbjct: 1027 SQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECP 1086
Query: 1420 VGWRGVHCDNATTEDNCNGT---------CHTSANCLTNSDGTASCKCAAGFQGNGTICT 1470
GW G++CD + C C+ ++ T C+C AG+ G+ C
Sbjct: 1087 SGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCV-DAGNTHHCRCQAGY--TGSYCE 1143
Query: 1471 AINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-INPCLENHGGCDKNAE 1529
+ E S C A C G C C AGY G+ C E I+ CL + C
Sbjct: 1144 DL-VDECSPSPCQNGATCTDYLGGYS-CKCVAGY--HGVNCSEEIDECLSHP--CQNGGT 1197
Query: 1530 CTQTGPNQAACNCLPAYTGDGKVCTL-INVCLTKNGGCSEFAICNHTGQ-VER----TCT 1583
C PN C+C P T G C + ++ C S C + G V++ +CT
Sbjct: 1198 CLDL-PNTYKCSC-PRGT-QGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT 1254
Query: 1584 CKPNYIGDGFTCRGSIYQELPKNP 1607
C P ++G+ C G + E NP
Sbjct: 1255 CPPGFVGE--RCEGDV-NECLSNP 1275
Score = 85.9 bits (211), Expect = 5e-16
Identities = 80/295 (27%), Positives = 104/295 (35%), Gaps = 63/295 (21%)
Query: 108 DCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCV 167
D EC A +PC C +G TC C EG+ GT CE D+ P C
Sbjct: 528 DVDEC---ASTPCKNGAKCLDG-PNTYTCVCTEGYTGTHCEVDIDECDPDP-------CH 576
Query: 168 HGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC----------------S 211
+G C G+ TC C YTG C+ I EC++ C C
Sbjct: 577 YGSCKDGV-ATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTG 635
Query: 212 PSTEDE------------------NKLECKCLPNYRGDGKYCD-PINPCLRKICHPHAHC 252
P+ E + EC C P Y G C+ I+ C CH C
Sbjct: 636 PNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY--TGSMCNINIDECAGNPCHNGGTC 693
Query: 253 TYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQ 312
G N +C C EGY D V+ C N P C+ D C+C +
Sbjct: 694 ED-GINGFTCRCPEGYH-DPTCLSEVNECNSN----PCVHGACR-DSLNGYKCDCDPGWS 746
Query: 313 NFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIME 367
G C + + NPC C + G C C++G+ G C NI E
Sbjct: 747 ----GTNCDINNNECESNPCVNGGTCKDMTSGYV-CTCREGF--SGPNCQTNINE 794
Score = 84.0 bits (206), Expect = 2e-15
Identities = 74/254 (29%), Positives = 98/254 (38%), Gaps = 38/254 (14%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C G+ G C+ C P N C+D Y+ C C GF+G CE
Sbjct: 933 CLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYT----CTCPAGFSGIHCE-----NN 983
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE-- 2063
PDC C + G C DGI S CLC G+TG C Q + + PC TC++
Sbjct: 984 TPDCTESSCFNGGTCVDGI-NSFTCLCPPGFTGSYC--QHDVNECDSQPCLHGGTCQDGC 1040
Query: 2064 -NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG-----D 2117
+ C C Y G +V +C D+ C +C Q T+ C C G+ G
Sbjct: 1041 GSYRCTCPQGYTGPNCQ-NLVHWC--DSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVP 1097
Query: 2118 GHSCTEIDPCADGLNGG--CHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCL 2175
SC E+ G++ C C G H C C++ Y G CE +D C
Sbjct: 1098 SVSC-EVAAQRQGVDVARLCQHGGLCVDAG-NTHHCRCQAGYTGS--YCED---LVDEC- 1149
Query: 2176 QDNGQCHADAKCVD 2189
C A C D
Sbjct: 1150 -SPSPCQNGATCTD 1162
Score = 83.2 bits (204), Expect = 3e-15
Identities = 79/321 (24%), Positives = 110/321 (34%), Gaps = 96/321 (29%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C +G+ G +CQ C P C N+G C+D + +C C + G CE+
Sbjct: 779 CREGFSGPNCQTNINECASNP---CLNQGTCIDDVAGY-KCNCLLPYTGATCEVVLA--- 831
Query: 2006 GPDCLPCGCSDHGQCDDGIT-GSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN 2064
C P C + G+C S C+C TGW G +C+ + PC A+C+
Sbjct: 832 --PCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVD--INECVLSPCRHGASCQNT 887
Query: 2065 N---TCECNLDYEG----------------------DGITCTVVD--------FCKQDNG 2091
+ C C Y G DGI D FC++D
Sbjct: 888 HGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDIN 947
Query: 2092 GCA-----KVARCSQKGTKVSCSCQKGYKG-----DGHSCTEID-----PCADGLNG--- 2133
CA A C+ +C+C G+ G + CTE C DG+N
Sbjct: 948 ECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTC 1007
Query: 2134 ---------------------GCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPID 2172
C TC+ G G ++C C Y G NC Q +
Sbjct: 1008 LCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-DGCGSYRCTCPQGYTGP--NC---QNLVH 1061
Query: 2173 RCLQDNGQCHADAKCVDLHFQ 2193
C D+ C KC H Q
Sbjct: 1062 WC--DSSPCKNGGKCWQTHTQ 1080
Score = 82.4 bits (202), Expect = 5e-15
Identities = 73/263 (27%), Positives = 101/263 (38%), Gaps = 32/263 (12%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGIC-LDGVNGTGVCECGEGFSGTAC-ETCTEGKYG 1392
EC G G C N C C + VNG +C C G++G AC + E G
Sbjct: 360 ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG 419
Query: 1393 IH-CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSD 1451
+ C+ A C++ LG C C G+ G C+ E N C A CL +
Sbjct: 420 ANPCEHAGKCIN------TLGSFECQCLQGYTGPRCEIDVNECVSN-PCQNDATCL-DQI 471
Query: 1452 GTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVC 1511
G C C G++G + +N E ++ C C C C G+TG +
Sbjct: 472 GEFQCICMPGYEG---VHCEVNTDECASSPCLHNGRCLDKI-NEFQCECPTGFTGH-LCQ 526
Query: 1512 LEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTL-INVC---LTKNGGCS 1567
+++ C C A+C GPN C C YTG C + I+ C G C
Sbjct: 527 YDVDECASTP--CKNGAKCLD-GPNTYTCVCTEGYTGTH--CEVDIDECDPDPCHYGSCK 581
Query: 1568 EFAICNHTGQVERTCTCKPNYIG 1590
+ G TC C+P Y G
Sbjct: 582 D-------GVATFTCLCRPGYTG 597
Score = 82.0 bits (201), Expect = 7e-15
Identities = 77/270 (28%), Positives = 101/270 (37%), Gaps = 36/270 (13%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVC--LDQYS-ATGECKCNTGFNGTACEMCWPGRFG 2006
C + G CQ PC N G C +D+ A C C GF+G C
Sbjct: 48 CGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLT----PLD 103
Query: 2007 PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATC---KE 2063
CL C + G CD +C C GW+G SC Q P + PC+ C +
Sbjct: 104 NACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSC--QQADPC-ASNPCANGGQCLPFEA 160
Query: 2064 NNTCECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCT 2122
+ C C + G TC V+ C Q G C C + C C+ + G
Sbjct: 161 SYICHCPPSFHGP--TCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERP 218
Query: 2123 EIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCH 2182
+ PC+ C TC+ TG H+C C + G NCE ID C +N C
Sbjct: 219 YV-PCSP---SPCQNGGTCRPTGDVTHECACLPGFTGQ--NCEEN---IDDCPGNN--CK 267
Query: 2183 ADAKCVDLHFQDTTVGVFHLRSP---LGQY 2209
CVD V ++ R P GQY
Sbjct: 268 NGGACVD------GVNTYNCRCPPEWTGQY 291
Score = 80.1 bits (196), Expect = 3e-14
Identities = 80/276 (28%), Positives = 96/276 (34%), Gaps = 33/276 (11%)
Query: 1326 KCVRTVITRECCAG--FFGPQCQPCPGNAQNVCFGNGICLDGVNGTGV----CECGEGFS 1379
KC T C G F GP+CQ C G C V+ GV C C GFS
Sbjct: 36 KCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTC-HVVDRRGVADYACSCALGFS 94
Query: 1380 GTACETCTEGKYGIHCDQAC---SCVH-GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDN 1435
G C T D AC C + G C+ L + C C GW G C A D
Sbjct: 95 GPLCLT--------PLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA---DP 143
Query: 1436 C-NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPG 1494
C + C CL + + C C F G T +N C G C C
Sbjct: 144 CASNPCANGGQCLP-FEASYICHCPPSFHG-PTCRQDVNECGQKPGLCRHGGTCHNEVGS 201
Query: 1495 RRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCT 1554
R C C+A +TG + PC + C C TG C CLP +TG C
Sbjct: 202 YR-CVCRATHTGPNCERPYV-PC--SPSPCQNGGTCRPTGDVTHECACLPGFTGQN--CE 255
Query: 1555 LINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
N+ C C G C C P + G
Sbjct: 256 -ENIDDCPGNNCKNGGAC-VDGVNTYNCRCPPEWTG 289
Score = 79.0 bits (193), Expect = 6e-14
Identities = 73/260 (28%), Positives = 105/260 (40%), Gaps = 44/260 (16%)
Query: 1336 CCAGFFGPQCQP----CPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKY 1391
C +G+ GP C C A N C G C++ + G+ C+C +G++G CE
Sbjct: 400 CPSGYTGPACSQDVDECSLGA-NPCEHAGKCINTL-GSFECQCLQGYTGPRCEIDVNECV 457
Query: 1392 GIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSD 1451
C +C+ +G+ C C G+ GVHC+ T++ + C + CL +
Sbjct: 458 SNPCQNDATCLD------QIGEFQCICMPGYEGVHCE-VNTDECASSPCLHNGRCL-DKI 509
Query: 1452 GTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD---- 1507
C+C GF G+ +C + E ++ C A C P C C GYTG
Sbjct: 510 NEFQCECPTGFTGH--LC-QYDVDECASTPCKNGAKC-LDGPNTYTCVCTEGYTGTHCEV 565
Query: 1508 GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCS 1567
I + +PC H G K+ T T C C P YTG + C T CS
Sbjct: 566 DIDECDPDPC---HYGSCKDGVATFT------CLCRPGYTG--------HHCETNINECS 608
Query: 1568 EFAICNHTGQVERTCTCKPN 1587
C H G TC + N
Sbjct: 609 S-QPCRHGG----TCQDRDN 623
Score = 78.6 bits (192), Expect = 7e-14
Identities = 80/309 (25%), Positives = 115/309 (37%), Gaps = 45/309 (14%)
Query: 1950 CCKGYFGRDCQACPGG-PDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C GY G C+ +PC + G CLD+ + +C+C TGF G C+ +
Sbjct: 478 CMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEF-QCECPTGFTGHLCQY-----DVDE 531
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE---NN 2065
C C + +C DG + C+C G+TG C+ C P + +CK+
Sbjct: 532 CASTPCKNGAKCLDG-PNTYTCVCTEGYTGTHCEVDI---DECDPDPCHYGSCKDGVATF 587
Query: 2066 TCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEID 2125
TC C Y G + + Q C C + C C KG G +D
Sbjct: 588 TCLCRPGYTGHHCETNINECSSQP---CRHGGTCQDRDNAYLCFCLKGTTGPNCE-INLD 643
Query: 2126 PCADGLNGGCHEHATC--KMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHA 2183
CA + C + TC K+ G ++C C+ Y G N + ID C CH
Sbjct: 644 DCA---SSPC-DSGTCLDKIDG---YECACEPGYTGSMCN-----INIDECA--GNPCHN 689
Query: 2184 DAKCVDLHFQDTTVGVFHLRSPLGQYKLT-FDKAREACANEAATMATYNQLSYAQKAKYH 2242
C D + F R P G + T + E +N A + L+ K
Sbjct: 690 GGTCED------GINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLN-GYKCD-- 740
Query: 2243 LCSAGWLET 2251
C GW T
Sbjct: 741 -CDPGWSGT 748
Score = 78.2 bits (191), Expect = 1e-13
Identities = 79/326 (24%), Positives = 117/326 (35%), Gaps = 47/326 (14%)
Query: 675 GTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPKCCKGFYG 734
G CV Y RCP ++G++ C + +P C+ G
Sbjct: 270 GACVDGVNTYNCRCPPE------------WTGQY------CTEDVDECQLMPNACQN--G 309
Query: 735 PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ------FCSDPN-KYGPR 787
C+ GG++ C D C F G+ C +C P+ + G
Sbjct: 310 GTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLL 369
Query: 788 CNKKCLCVHGTCNNRIDSDGACLTG----TCRDGSAGRLCDKQTSACGPYVQFCHIHATC 843
C+ C+ CN + D + G TC G G C + C C C
Sbjct: 370 CHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKC 429
Query: 844 EYSNGTASCICKAGYEGDGTLCS-EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT 902
+ G+ C C GY G C +++ C C +A C+ G C+C G+
Sbjct: 430 INTLGSFECQCLQGY--TGPRCEIDVNECVS---NPCQNDATCLDQ-IGEFQCICMPGY- 482
Query: 903 GNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTG 962
G C E+N S+ C N CL + +CEC GF G+ + + C +
Sbjct: 483 -EGVHC-EVNTDECASS-PCLHNGRCL-DKINEFQCECPTGFTGHLCQYD-VDEC--AST 535
Query: 963 KCHPLASCQSTSSGVWSCVCQEGYEG 988
C A C ++CVC EGY G
Sbjct: 536 PCKNGAKCLD-GPNTYTCVCTEGYTG 560
Score = 78.2 bits (191), Expect = 1e-13
Identities = 77/265 (29%), Positives = 104/265 (39%), Gaps = 41/265 (15%)
Query: 1335 ECCAGFFGPQCQ-PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
EC GF G CQ A C CLDG N T C C EG++GT CE +
Sbjct: 515 ECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN-TYTCVCTEGYTGTHCEVDID----- 568
Query: 1394 HCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT-CHTSANCLTNSDG 1452
CD C +G C G + +C C G+ G HC+ T + C+ C C + D
Sbjct: 569 ECDPD-PCHYGSCKDG-VATFTCLCRPGYTGHHCE--TNINECSSQPCRHGGTC-QDRDN 623
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRV----CTCKAGYTGDG 1508
C C G G CEI+ C A + C T ++ C C+ GYTG
Sbjct: 624 AYLCFCLKGTTGPN--------CEINLDDC-ASSPCDSGTCLDKIDGYECACEPGYTG-S 673
Query: 1509 IVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK---NGG 1565
+ + I+ C N C C + G N C C Y D + +N C + +G
Sbjct: 674 MCNINIDECAGN--PCHNGGTC-EDGINGFTCRCPEGY-HDPTCLSEVNECNSNPCVHGA 729
Query: 1566 CSEFAICNHTGQVERTCTCKPNYIG 1590
C + + G C C P + G
Sbjct: 730 CRD----SLNGY---KCDCDPGWSG 747
Score = 77.8 bits (190), Expect = 1e-13
Identities = 71/271 (26%), Positives = 105/271 (38%), Gaps = 57/271 (21%)
Query: 1950 CCKGYFGRDCQA-CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G CQ PC N CLD + T C C G+ GT CE+ +
Sbjct: 516 CPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN-TYTCVCTEGYTGTHCEVDID-----E 569
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCE 2068
C P C +G C DG+ + CLC G+TG C+T + + PC TC++ +
Sbjct: 570 CDPDPCH-YGSCKDGVA-TFTCLCRPGYTGHHCETN--INECSSQPCRHGGTCQDRDNAY 625
Query: 2069 CNLDYEG-DGITCTV-VDFCKQ---DNGGCAKVARCSQKGTKVSCSCQKGYKGD------ 2117
+G G C + +D C D+G C K C+C+ GY G
Sbjct: 626 LCFCLKGTTGPNCEINLDDCASSPCDSG------TCLDKIDGYECACEPGYTGSMCNINI 679
Query: 2118 ----GHSCTEIDPCADGLNG-------GCHE----------------HATCKMTGPGKHK 2150
G+ C C DG+NG G H+ H C+ + G +K
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNG-YK 738
Query: 2151 CECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
C+C + G + + + C+ + G C
Sbjct: 739 CDCDPGWSGTNCDINNNECESNPCV-NGGTC 768
Score = 76.3 bits (186), Expect = 4e-13
Identities = 68/252 (26%), Positives = 98/252 (38%), Gaps = 43/252 (17%)
Query: 1950 CCKGYFG----RDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C GY G +D C G + PC + G C++ + EC+C G+ G CE+
Sbjct: 400 CPSGYTGPACSQDVDECSLGAN-PCEHAGKCINTLGSF-ECQCLQGYTGPRCEIDVN--- 454
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENN 2065
+C+ C + C D I G QC+C G+ G C+ + PC + C +
Sbjct: 455 --ECVSNPCQNDATCLDQI-GEFQCICMPGYEGVHCEVNT--DECASSPCLHNGRCLDKI 509
Query: 2066 T---CECNLDYEGDGITCTVVDFCKQDNGGCAKV-----ARCSQKGTKVSCSCQKGYKGD 2117
CEC + G C+ D CA A+C +C C +GY G
Sbjct: 510 NEFQCECPTGFTG--------HLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGT 561
Query: 2118 GHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQD 2177
H +ID C CH + +CK G C C+ Y G +CE I+ C
Sbjct: 562 -HCEVDIDECDP---DPCH-YGSCK-DGVATFTCLCRPGYTGH--HCETN---INEC--S 608
Query: 2178 NGQCHADAKCVD 2189
+ C C D
Sbjct: 609 SQPCRHGGTCQD 620
Score = 75.5 bits (184), Expect = 6e-13
Identities = 75/312 (24%), Positives = 102/312 (32%), Gaps = 70/312 (22%)
Query: 101 CPGRW-GPDCIECPGGAGSPCNGRGSCAEGMEGNGT----CSCQEGFGGTACETCADDNL 155
C G + GP C + +PC G+C ++ G CSC GF G C T D+
Sbjct: 48 CGGAFVGPRCQDPNPCLSTPCKNAGTC-HVVDRRGVADYACSCALGFSGPLCLTPLDNAC 106
Query: 156 F---------------------------GPSCSSVCNCVHGVCNSG-----LDGDGTCEC 183
G SC C C +G + C C
Sbjct: 107 LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166
Query: 184 YSAYTGPKCDKPIPECAAL--LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PINP 240
++ GP C + + EC LC C + C C + G C+ P P
Sbjct: 167 PPSFHGPTCRQDVNECGQKPGLCRHGGTCH---NEVGSYRCVCRATHTGPN--CERPYVP 221
Query: 241 CLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCK---- 296
C C C G H C C G+ G C+ N +CP + CK
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQN--------CEENIDDCPGNN--CKNGGA 271
Query: 297 -YDGPGQSHCECKEHYQNFVPGVGCSM-TDICK-SDNPCHRNANCTTVAPGRTECICQKG 353
DG +C C + G C+ D C+ N C C G C+C G
Sbjct: 272 CVDGVNTYNCRCPPEW----TGQYCTEDVDECQLMPNACQNGGTCHN-THGGYNCVCVNG 326
Query: 354 YVGDGLTCYGNI 365
+ G+ C NI
Sbjct: 327 WTGE--DCSENI 336
Score = 75.1 bits (183), Expect = 8e-13
Identities = 82/296 (27%), Positives = 109/296 (36%), Gaps = 93/296 (31%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C GY G C C G P C+N G C D G NG C C G
Sbjct: 666 CEPGYTGSMCNINIDECAGNP---CHNGGTCED------------GINGFTCR-CPEGYH 709
Query: 2006 GPDCLP----CGCSD--HGQCDDGITGSGQCLCETGWTGPSCD----------------- 2042
P CL C + HG C D + G +C C+ GW+G +CD
Sbjct: 710 DPTCLSEVNECNSNPCVHGACRDSLNGY-KCDCDPGWSGTNCDINNNECESNPCVNGGTC 768
Query: 2043 -------------------TQAVLPAVCTPPCSAHATCKEN---NTCECNLDYEGDGITC 2080
Q + + PC TC ++ C C L Y G TC
Sbjct: 769 KDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPY--TGATC 826
Query: 2081 TVV------DFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSC-TEIDPCADGLNG 2133
VV C+ NGG R S+ SC C G++ G +C +I+ C +
Sbjct: 827 EVVLAPCAPSPCR--NGG---ECRQSEDYESFSCVCPTGWQ--GQTCEVDINEC---VLS 876
Query: 2134 GCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
C A+C+ T G ++C C++ Y G NCE + ID C + CH C D
Sbjct: 877 PCRHGASCQNT-HGGYRCHCQAGY--SGRNCETD---IDDCRPN--PCHNGGSCTD 924
Score = 74.7 bits (182), Expect = 1e-12
Identities = 87/328 (26%), Positives = 125/328 (38%), Gaps = 63/328 (19%)
Query: 1903 GSCVN-----TPSCPRW---SKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGY 1954
G+CV+ + +CP + +G +CL N R + C +R + C G+
Sbjct: 1242 GTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHC--ECRAGH 1299
Query: 1955 FGRDCQACPGG-PDAPCNNRGVC-LDQYSATGE-CKCNTGFNGTACEMCWPGRFGPDCLP 2011
GR C++ G PC N G C + +A G CKC GF G CE D
Sbjct: 1300 TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEN--------DART 1351
Query: 2012 CG---CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCK---ENN 2065
CG C + G C G S CLC +TGP C A P + PC TC+ E+
Sbjct: 1352 CGSLRCLNGGTCISG-PRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESP 1410
Query: 2066 TCECNLDYEGDGITCTVVDFCKQDNGG----------CAKVARCSQKGTKVSCSCQ---- 2111
C + +G+ C ++D+ G ++ C + CS Q
Sbjct: 1411 FYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNH 1470
Query: 2112 -KGYKGDGHSCTEIDPCADGLNGGCHEHATC-KMTGPGKHKCECKS-HYVGDGLNCEPEQ 2168
G+ G S DP + C + C K G +C S + DG +C+
Sbjct: 1471 ACGWDGGDCSLNFNDPWKN-----CTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQ--- 1522
Query: 2169 LPIDRCLQDNGQCHA--DAKCVDLHFQD 2194
+ GQC+ D C D HF D
Sbjct: 1523 -------RAEGQCNPLYDQYCKD-HFSD 1542
Score = 72.8 bits (177), Expect = 4e-12
Identities = 78/301 (25%), Positives = 105/301 (34%), Gaps = 64/301 (21%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET---------- 1385
C G+ G C+ +G +G C C G+SG CET
Sbjct: 857 CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPC 916
Query: 1386 -----CTEGKYGIHCD-------QACSCVHGRCNQGPLGDG----------SCDCDVGWR 1423
CT+G CD C C P +G +C C G+
Sbjct: 917 HNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFS 976
Query: 1424 GVHCDNAT---TEDNC--NGTCHTSANCLTNSDGTASCKCAAGFQGNGTICT-AINACEI 1477
G+HC+N T TE +C GTC N T C C GF G+ C +N C+
Sbjct: 977 GIHCENNTPDCTESSCFNGGTCVDGINSFT-------CLCPPGF--TGSYCQHDVNECD- 1026
Query: 1478 SNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQ 1537
+ C C+ R CTC GYTG L ++ C + C +C QT Q
Sbjct: 1027 -SQPCLHGGTCQDGCGSYR-CTCPQGYTGPNCQNL-VHWC--DSSPCKNGGKCWQT-HTQ 1080
Query: 1538 AACNCLPAYTGDGKVCTLINV---CLTKNGGCSEFAICNHTGQV-----ERTCTCKPNYI 1589
C C +T G C + +V + G +C H G C C+ Y
Sbjct: 1081 YRCECPSGWT--GLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYT 1138
Query: 1590 G 1590
G
Sbjct: 1139 G 1139
Score = 71.6 bits (174), Expect = 9e-12
Identities = 74/258 (28%), Positives = 102/258 (39%), Gaps = 43/258 (16%)
Query: 1949 RCCKGYFGRDC-QACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM----CWPG 2003
+C GY G +C + PC N G CLD + T +C C G G CE+ C P
Sbjct: 1170 KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPN-TYKCSCPRGTQGVHCEINVDDCNP- 1227
Query: 2004 RFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHAT--C 2061
P C ++G C D + G C C G+ G C+ + + PC A T C
Sbjct: 1228 PVDPVSRSPKCFNNGTCVDQV-GGYSCTCPPGFVGERCEGD--VNECLSNPCDARGTQNC 1284
Query: 2062 KENNT---CECNLDYEGDGITCTVVDFCKQ---DNGGCAKVARCSQKGTKVSCSCQKGYK 2115
+ CEC + G +V++ CK NGG VA + +G C C G++
Sbjct: 1285 VQRVNDFHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCAVASNTARG--FICKCPAGFE 1341
Query: 2116 G-----DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPE-QL 2169
G D +C + C LNGG TC ++GP C C + G PE Q
Sbjct: 1342 GATCENDARTCGSL-RC---LNGG-----TC-ISGPRSPTCLCLGPFTG------PECQF 1385
Query: 2170 PIDRCLQDNGQCHADAKC 2187
P C+ C
Sbjct: 1386 PASSPCLGGNPCYNQGTC 1403
Score = 70.1 bits (170), Expect = 3e-11
Identities = 77/295 (26%), Positives = 107/295 (36%), Gaps = 57/295 (19%)
Query: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE----------- 1384
C G+ G CQ A N C G CL + +C C F G C
Sbjct: 129 CPPGWSGKSCQQADPCASNPCANGGQCLP-FEASYICHCPPSFHGPTCRQDVNECGQKPG 187
Query: 1385 ------TCTE--GKY---------GIHCDQA-CSCVHGRCNQG----PLGD--GSCDCDV 1420
TC G Y G +C++ C C G P GD C C
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLP 247
Query: 1421 GWRGVHCDNATTEDNCNG-TCHTSANCLTNSDGTASCKCAAGFQGNGTICTA-INACEIS 1478
G+ G +C+ D+C G C C+ DG + C + G CT ++ C++
Sbjct: 248 GFTGQNCEE--NIDDCPGNNCKNGGACV---DGVNTYNCRCPPEWTGQYCTEDVDECQLM 302
Query: 1479 NGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-INPCLENHGGCDKNAECTQTGPNQ 1537
C C T G C C G+TG+ C E I+ C C A C
Sbjct: 303 PNACQNGGTCHNTHGGYN-CVCVNGWTGED--CSENIDDCAS--AACFHGATCHD---RV 354
Query: 1538 AACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQV--ERTCTCKPNYIG 1590
A+ C + G +C L + C+ + C+E + C+ T V + CTC Y G
Sbjct: 355 ASFYCECPHGRTGLLCHLNDACI--SNPCNEGSNCD-TNPVNGKAICTCPSGYTG 406
Score = 69.7 bits (169), Expect = 3e-11
Identities = 57/245 (23%), Positives = 78/245 (31%), Gaps = 43/245 (17%)
Query: 157 GPSCSSVCN-CVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS-PST 214
GP CS C++G +G C C A+ GP+C P P C + C C
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNP-CLSTPCKNAGTCHVVDR 79
Query: 215 EDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG---- 270
C C + G N CL C C L + C C G+ G
Sbjct: 80 RGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ 139
Query: 271 -----------DGQVCLPVD--------------PCQINFGNCPTKSTVCKYDGP----- 300
+G CLP + C+ + C K +C++ G
Sbjct: 140 QADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEV 199
Query: 301 GQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLT 360
G C C+ + G C + S +PC C EC C G+ G
Sbjct: 200 GSYRCVCRATH----TGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQ--N 253
Query: 361 CYGNI 365
C NI
Sbjct: 254 CEENI 258
Score = 67.8 bits (164), Expect = 1e-10
Identities = 69/282 (24%), Positives = 99/282 (35%), Gaps = 43/282 (15%)
Query: 99 RCCPGRWGPDCIE-CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADD---- 153
+C G G +C E PC G+C + + CSC G G CE DD
Sbjct: 1170 KCVAGYHGVNCSEEIDECLSHPCQNGGTCLD-LPNTYKCSCPRGTQGVHCEINVDDCNPP 1228
Query: 154 ---NLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRC 210
P C + CV V G +C C + G +C+ + EC + C
Sbjct: 1229 VDPVSRSPKCFNNGTCVDQV------GGYSCTCPPGFVGERCEGDVNECLSNPCDARG-T 1281
Query: 211 SPSTEDENKLECKCLPNYRGDGKYCDP-INPCLRKICHPHAHCTYLGPNRHS--CTCQEG 267
+ N C+C + G+ C+ IN C K C C C C G
Sbjct: 1282 QNCVQRVNDFHCECRAGH--TGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAG 1339
Query: 268 YRG-----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSM 322
+ G D + C + C +N G C GP C C + P
Sbjct: 1340 FEGATCENDARTCGSL-RC-LNGGTC--------ISGPRSPTCLCLGPFTG--PECQFPA 1387
Query: 323 TDICKSDNPCHRNANC--TTVAPGRTECICQKGYVGDGLTCY 362
+ C NPC+ C T+ +P C+C + +GL C+
Sbjct: 1388 SSPCLGGNPCYNQGTCEPTSESP-FYRCLCPAKF--NGLLCH 1426
Score = 65.9 bits (159), Expect = 5e-10
Identities = 76/310 (24%), Positives = 112/310 (36%), Gaps = 57/310 (18%)
Query: 727 KCCKGFYGPDCNQCPGGFS-NPCSGNGQCADSLGGNGTCICEEGFQGSQC-----QFCSD 780
+C G+ G C S +PC C D LGG +C C G+ G C + S
Sbjct: 1132 RCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGY-SCKCVAGYHGVNCSEEIDECLSH 1190
Query: 781 PNKYGPRC-----NKKCLCVHGT-----------CNNRID---------SDGACL----- 810
P + G C KC C GT CN +D ++G C+
Sbjct: 1191 PCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGG 1250
Query: 811 -TGTCRDGSAGRLCDKQTSACGPYVQFCHIHAT--CEYSNGTASCICKAGYEGDGTLC-S 866
+ TC G G C+ + C C T C C C+AG+ G C S
Sbjct: 1251 YSCTCPPGFVGERCEGDVNEC--LSNPCDARGTQNCVQRVNDFHCECRAGH--TGRRCES 1306
Query: 867 EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNA 926
++ C G C C +C+ G C N+ + C +
Sbjct: 1307 VINGCKGKP---CKNGGTCAVASNTARGFICKCPAGFEGATCE--NDARTCGSLRCLNGG 1361
Query: 927 SCLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHPLASCQSTS-SGVWSCVCQE 984
+C+ GP C C F G +C+ P +S C+ +C+ TS S + C+C
Sbjct: 1362 TCI-SGPRSPTCLCLGPF--TGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPA 1418
Query: 985 GYEGDGFLCY 994
+ +G LC+
Sbjct: 1419 KF--NGLLCH 1426
Score = 65.1 bits (157), Expect = 9e-10
Identities = 55/190 (28%), Positives = 70/190 (36%), Gaps = 35/190 (18%)
Query: 1356 CFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQ--ACSCVHGRCNQGPLGD 1413
CF NG C+D V G C C GF G CE CD +CV + D
Sbjct: 1238 CFNNGTCVDQVGGYS-CTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ------RVND 1290
Query: 1414 GSCDCDVGWRGVHCDNATTEDNCNG-TCHTSANCLTNSDGTAS--CKCAAGFQG-----N 1465
C+C G G C++ + C G C C S+ CKC AGF+G +
Sbjct: 1291 FHCECRAGHTGRRCESVI--NGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCEND 1348
Query: 1466 GTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD------GIVCLEINPCLE 1519
C ++ NGG P C C +TG CL NPC
Sbjct: 1349 ARTCGSLRCL---NGGTCISG------PRSPTCLCLGPFTGPECQFPASSPCLGGNPCY- 1398
Query: 1520 NHGGCDKNAE 1529
N G C+ +E
Sbjct: 1399 NQGTCEPTSE 1408
Score = 63.9 bits (154), Expect = 2e-09
Identities = 85/319 (26%), Positives = 118/319 (36%), Gaps = 85/319 (26%)
Query: 1335 ECCAGFFGPQCQ----PCPGNAQN-------VCFGNGICLDGVNGTGVCECGEGFSGTAC 1383
EC +G+ G C C AQ +C G+C+D N T C C G++G+ C
Sbjct: 1084 ECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGN-THHCRCQAGYTGSYC 1142
Query: 1384 E---------------TCTE-----------GKYGIHCDQACS-CVHGRCNQGPL----- 1411
E TCT+ G +G++C + C+ C G
Sbjct: 1143 EDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLP 1202
Query: 1412 GDGSCDCDVGWRGVHCDNATTEDNCN---------GTCHTSANCLTNSDGTASCKCAAGF 1462
C C G +GVHC+ D+CN C + C+ + G SC C GF
Sbjct: 1203 NTYKCSCPRGTQGVHCE--INVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGF 1259
Query: 1463 QGNGTICTA-INACEISNGGCSAKA--DCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLE 1519
G C +N C +SN C A+ +C + C C+AG+TG + IN C
Sbjct: 1260 VGER--CEGDVNEC-LSN-PCDARGTQNCVQRVNDFH-CECRAGHTGRRCESV-INGC-- 1311
Query: 1520 NHGGCDKNAECTQTGPNQA---ACNCLPAYTG-----DGKVCTLINVCLTKNGGCSEFAI 1571
G KN N A C C + G D + C + CL NGG
Sbjct: 1312 -KGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLR-CL--NGGTC---- 1363
Query: 1572 CNHTGQVERTCTCKPNYIG 1590
+G TC C + G
Sbjct: 1364 --ISGPRSPTCLCLGPFTG 1380
Score = 54.7 bits (130), Expect = 1e-06
Identities = 50/194 (25%), Positives = 73/194 (37%), Gaps = 31/194 (15%)
Query: 2006 GPDCLPCG--CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCK- 2062
GP C G C + G+C+ G+ C+C + GP C Q P + T PC TC
Sbjct: 21 GPRCSQPGETCLNGGKCE-AANGTEACVCGGAFVGPRC--QDPNPCLST-PCKNAGTCHV 76
Query: 2063 ------ENNTCECNLDYEGDGITCTVVDFCKQD---NGGCAKVARCSQKGTKVSCSCQKG 2113
+ C C L + G + + C + NGG + T+ C C G
Sbjct: 77 VDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTL----TEYKCRCPPG 132
Query: 2114 YKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDR 2173
+ G SC + DPCA + C C + + C C + G C + ++
Sbjct: 133 W--SGKSCQQADPCA---SNPCANGGQC-LPFEASYICHCPPSF--HGPTCRQD---VNE 181
Query: 2174 CLQDNGQCHADAKC 2187
C Q G C C
Sbjct: 182 CGQKPGLCRHGGTC 195
Score = 53.9 bits (128), Expect = 2e-06
Identities = 80/298 (26%), Positives = 106/298 (35%), Gaps = 79/298 (26%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNG--QCADSLGGNGTCICEEGFQGSQCQFCSD- 780
C GF G C N+C SNPC G C + + C C G G +C+ +
Sbjct: 1255 CPPGFVGERCEGDVNEC---LSNPCDARGTQNCVQRVN-DFHCECRAGHTGRRCESVING 1310
Query: 781 ----PNKYGPRCNKK--------CLCVHG----TCNNRIDSDGA--CLTG-TCRDGSAGR 821
P K G C C C G TC N + G+ CL G TC G
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370
Query: 822 LCDKQTSACGPYVQF-----------CHIHATCEYSNGTA--SCICKAGYEGDGTLCSEM 868
C GP QF C+ TCE ++ + C+C A + +G LC +
Sbjct: 1371 TCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKF--NGLLCHIL 1428
Query: 869 DPCTGLTPGGCSRN------------AECIKTGTGTHTCVCQ-----QGWTGNGRDCSEI 911
D G GG R+ EC + G C Q GW +G DCS
Sbjct: 1429 DYSFG---GGAGRDIPPPLIEEACELPEC-QEDAGNKVCSLQCNNHACGW--DGGDCSLN 1482
Query: 912 NNCLLPSAGGCHDNASC-LYVGPGQNECECKK-GFRGNGIDCEPITSCLEQTGKCHPL 967
N C + C Y G + +C G +G DC+ G+C+PL
Sbjct: 1483 FN---DPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQ------RAEGQCNPL 1531
Score = 53.1 bits (126), Expect = 3e-06
Identities = 75/317 (23%), Positives = 111/317 (35%), Gaps = 63/317 (19%)
Query: 1336 CCAGFFGPQCQPCPGNA-QNVCFGNGI--CLDGVNGTGVCECGEGFSGTACETCTEGKYG 1392
C GF G +C+ N C G C+ VN CEC G +G CE+ G G
Sbjct: 1255 CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFH-CECRAGHTGRRCESVINGCKG 1313
Query: 1393 IHCDQACSC-VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNG-TCHTSANCLTNS 1450
C +C V +G + C C G+ G C+N C C C+ +
Sbjct: 1314 KPCKNGGTCAVASNTARGFI----CKCPAGFEGATCENDAR--TCGSLRCLNGGTCI-SG 1366
Query: 1451 DGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT--TPGRRVCTCKAGYTGDG 1508
+ +C C F G A + C + C + C+ T +P R C C A + +G
Sbjct: 1367 PRSPTCLCLGPFTGPECQFPASSPC-LGGNPCYNQGTCEPTSESPFYR-CLCPAKF--NG 1422
Query: 1509 IVC-----------------------LEINPCLENHGGCDKNAECTQTGPNQAACNCLPA 1545
++C E+ C E+ G + +C +C
Sbjct: 1423 LLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLN 1482
Query: 1546 YTGDGKVCTLINVC--LTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQEL 1603
+ K CT C +G C + CN G + DGF C+ + E
Sbjct: 1483 FNDPWKNCTQSLQCWKYFSDGHCD--SQCNSAG-----------CLFDGFDCQRA---EG 1526
Query: 1604 PKNPKTSQYFFQLQEHF 1620
NP QY ++HF
Sbjct: 1527 QCNPLYDQY---CKDHF 1540
Score = 48.5 bits (114), Expect = 8e-05
Identities = 39/166 (23%), Positives = 61/166 (36%), Gaps = 24/166 (14%)
Query: 830 CGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAEC---I 886
C + C CE +NGT +C+C + G C + +PC TP C C
Sbjct: 24 CSQPGETCLNGGKCEAANGTEACVCGGAFV--GPRCQDPNPCLS-TP--CKNAGTCHVVD 78
Query: 887 KTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRG 946
+ G + C C G++G N CL C + +C + + +C C G+ G
Sbjct: 79 RRGVADYACSCALGFSGPLCLTPLDNACL---TNPCRNGGTCDLLTLTEYKCRCPPGWSG 135
Query: 947 NGIDCEPITSCLEQT----GKCHPLASCQSTSSGVWSCVCQEGYEG 988
C+ C G+C P + + C C + G
Sbjct: 136 K--SCQQADPCASNPCANGGQCLPFEAS-------YICHCPPSFHG 172
Score = 44.3 bits (103), Expect = 0.002
Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 19/143 (13%)
Query: 1335 ECCAGFFGPQCQP----CPGNAQNVCFGNGICLDGVNGTG--VCECGEGFSGTACETCTE 1388
EC AG G +C+ C G C G C N +C+C GF G CE
Sbjct: 1294 ECRAGHTGRRCESVINGCKGKP---CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR 1350
Query: 1389 GKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGT-CHTSANCL 1447
+ C +C+ G + +C C + G C + G C+ C
Sbjct: 1351 TCGSLRCLNGGTCISGPRSP------TCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCE 1404
Query: 1448 TNSDGT-ASCKCAAGFQGNGTIC 1469
S+ C C A F NG +C
Sbjct: 1405 PTSESPFYRCLCPAKF--NGLLC 1425
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 101 bits (252), Expect = 8e-21
Identities = 83/276 (30%), Positives = 114/276 (41%), Gaps = 31/276 (11%)
Query: 720 NATVKIPKCCKGFYGPDCNQCPGG-FSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFC 778
++T + C GF GPDC P S+ C G C D L TC+C E + G C
Sbjct: 256 DSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGL-DTYTCLCPETWTGWDCSED 314
Query: 779 SD--PNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQF 836
D + P C GTC N S C G G C++ C
Sbjct: 315 VDECETQGPPHCRN-----GGTCQNSAGS----FHCVCVSGWGGTSCEENLDDC--IAAT 363
Query: 837 CHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTG-TGTHTC 895
C +TC G+ SC+C G G LC D C C +A+C TG+ C
Sbjct: 364 CAPGSTCIDRVGSFSCLCPPG--RTGLLCHLEDMCLSQP---CHGDAQCSTNPLTGSTLC 418
Query: 896 VCQQGWTGNGRDC-SEINNCLLPSAG--GCHDNASCLYVGPGQNECECKKGFRGNGIDCE 952
+CQ G+ +G C +++ CL+ G C SCL PG C C G+ G+ + +
Sbjct: 419 LCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCLCPPGYTGSRCEAD 475
Query: 953 PITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
CL Q CHP ++C + + C+C G EG
Sbjct: 476 H-NECLSQ--PCHPGSTCLDLLA-TFHCLCPPGLEG 507
Score = 100 bits (248), Expect = 2e-20
Identities = 91/322 (28%), Positives = 118/322 (36%), Gaps = 40/322 (12%)
Query: 43 CRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCP 102
C++ A + C G+ G C + + PG I R C P
Sbjct: 332 CQNSAGSFHCVCVSGW--------GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPP 383
Query: 103 GRWGPDCIECPGGAGSPCNGRGSCAEG-MEGNGTCSCQEGFGGTACETCADDNLFGPSCS 161
GR G C PC+G C+ + G+ C CQ G+ G C D+ L
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
Query: 162 SVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLE 221
S C HG G C C YTG +C+ EC + C S C
Sbjct: 444 SPCE--HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLA---TFH 498
Query: 222 CKCLPNYRGDGKYCD-PINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG-----DGQVC 275
C C P +G+ C+ N C C HA C L N C C G+ G D C
Sbjct: 499 CLCPPGL--EGQLCEVETNECASAPCLNHADCHDL-LNGFQCICLPGFSGTRCEEDIDEC 555
Query: 276 LPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC-SMTDICKSDNPCHR 334
PC N G C D PG HC+C ++ G C + D C SD PC
Sbjct: 556 RS-SPC-ANGGQC--------QDQPGAFHCKCLPGFE----GPRCQTEVDECLSD-PCPV 600
Query: 335 NANCTTVAPGRTECICQKGYVG 356
A+C + PG C+C G+ G
Sbjct: 601 GASCLDL-PGAFFCLCPSGFTG 621
Score = 99.4 bits (246), Expect = 4e-20
Identities = 89/301 (29%), Positives = 122/301 (40%), Gaps = 57/301 (18%)
Query: 728 CCKGFYGPDCNQCPGG-FSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ---------- 776
C G+ GP+C GG S PC+ G C G C C G+ G C
Sbjct: 679 CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGY-NCTCPTGYTGPTCSEEMTACHSGP 737
Query: 777 --------------FCS-DPNKYGPRCNKKC-LCVH------GTCNNRIDSDGACLTGTC 814
+C+ P+ GP+C CV GTC NR +CL C
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR-PGTFSCL---C 793
Query: 815 RDGSAGRLCD-KQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTG 873
G G C+ K +C C ATC+ S C+C GY G G+ + MD C
Sbjct: 794 AMGFQGPRCEGKLRPSCAD--SPCRNRATCQDSPQGPRCLCPTGYTG-GSCQTLMDLC-- 848
Query: 874 LTPGGCSRNAECIKTGTGTHTCVCQQGWTGN--GRDCSEINNCLLPS----AGGCHDNAS 927
C RN+ C++TG H C+C QGWTG S L + CH+
Sbjct: 849 -AQKPCPRNSHCLQTGPSFH-CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
Query: 928 CLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE 987
C+ GP C C GF+G+ + + + C ++ C A+C + SG + C C GY+
Sbjct: 907 CVDSGPSY-FCHCPPGFQGS-LCQDHVNPC--ESRPCQNGATCMAQPSG-YLCQCAPGYD 961
Query: 988 G 988
G
Sbjct: 962 G 962
Score = 99.4 bits (246), Expect = 4e-20
Identities = 83/284 (29%), Positives = 112/284 (39%), Gaps = 41/284 (14%)
Query: 100 CCPGRWGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
C P GP C +PC G+C G +C C GF G CE P
Sbjct: 755 CPPSHTGPQCQTSTDYCVSAPCFNGGTCVN-RPGTFSCLCAMGFQGPRCE-----GKLRP 808
Query: 159 SCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
SC+ C G C C + YTG C + CA CP NS C +
Sbjct: 809 SCADSPCRNRATCQDSPQGP-RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHC---LQTGP 864
Query: 219 KLECKCLPNYRGDGKYCD-PINPC----------LRKICHPHAHCTYLGPNRHSCTCQEG 267
C CL + G C+ P++ C + +CH C GP+ + C C G
Sbjct: 865 SFHCLCLQGW--TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCHCPPG 921
Query: 268 YRGDGQVCLP-VDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSM-TDI 325
++ G +C V+PC+ + P ++ P C+C Y G CS D
Sbjct: 922 FQ--GSLCQDHVNPCE----SRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDA 971
Query: 326 CKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERL 369
C+S PCH + CT PG C C G+V GL C G++ E L
Sbjct: 972 CQS-QPCHNHGTCTP-KPGGFHCACPPGFV--GLRCEGDVDECL 1011
Score = 96.3 bits (238), Expect = 3e-19
Identities = 100/364 (27%), Positives = 143/364 (39%), Gaps = 77/364 (21%)
Query: 675 GTCVSCSLVYWSRCPA-------NSEPTALFTHRCVYSGRFGSLKSGCARYCNATVKIPK 727
GTC Y CP + E TA + C+ G G YC
Sbjct: 704 GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY--YCT------- 754
Query: 728 CCKGFYGPDCNQCPGG-FSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ-----FCSD- 780
C GP C S PC G C + G +C+C GFQG +C+ C+D
Sbjct: 755 CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR-PGTFSCLCAMGFQGPRCEGKLRPSCADS 813
Query: 781 ---------PNKYGPRCNKKCLCVHGTCNNRID--------SDGACL-TG-----TCRDG 817
+ GPRC G+C +D + CL TG C G
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG 873
Query: 818 SAGRLCDKQTSACGPYV--------QFCHIHATCEYSNGTASCICKAGYEGDGTLCSE-M 868
G LC+ S+C CH C S + C C G++ G+LC + +
Sbjct: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ--GSLCQDHV 931
Query: 869 DPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCHDNAS 927
+PC C A C+ +G + C C G+ +G++CS E++ C + CH++ +
Sbjct: 932 NPCESRP---CQNGATCMAQPSG-YLCQCAPGY--DGQNCSKELDAC---QSQPCHNHGT 982
Query: 928 CLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHP--LASCQSTSSGVWSCVCQE 984
C PG C C GF G+ CE + CL+Q CHP A+C S ++ + C C
Sbjct: 983 CT-PKPGGFHCACPPGF--VGLRCEGDVDECLDQ--PCHPTGTAACHSLANAFY-CQCLP 1036
Query: 985 GYEG 988
G+ G
Sbjct: 1037 GHTG 1040
Score = 93.6 bits (231), Expect = 2e-18
Identities = 72/248 (29%), Positives = 91/248 (36%), Gaps = 49/248 (19%)
Query: 742 GGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNN 801
G F PC+ G C G GTC C GF G CQF DP C LC +G
Sbjct: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF-PDP------CQNAQLCQNG---- 77
Query: 802 RIDSDGACLTGTCRDGSAGRL-CDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEG 860
G+C+ L S P + C C G+ G
Sbjct: 78 ----------GSCQALLPAPLGLPSSPSPLTP----------------SFLCTCLPGFTG 111
Query: 861 DGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAG 920
+ DPC P CS+ C +G C C GWT G C + C SA
Sbjct: 112 ERCQAKLEDPC---PPSFCSKRGRCHIQASGRPQCSCMPGWT--GEQCQLRDFC---SAN 163
Query: 921 GCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSC 980
C + CL P Q +C C GF G+ + + C + G C SC +T G + C
Sbjct: 164 PCVNGGVCLATYP-QIQCHCPPGFEGHACE-RDVNECFQDPGPCPKGTSCHNT-LGSFQC 220
Query: 981 VCQEGYEG 988
+C G EG
Sbjct: 221 LCPVGQEG 228
Score = 93.2 bits (230), Expect = 3e-18
Identities = 80/294 (27%), Positives = 108/294 (36%), Gaps = 55/294 (18%)
Query: 1950 CCKGYFGRDCQACPGG-PDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C + G CQ APC N G C+++ T C C GF G CE G+ P
Sbjct: 755 CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR-PGTFSCLCAMGFQGPRCE----GKLRPS 809
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT-- 2066
C C + C D G +CLC TG+TG SC Q ++ PC ++ C +
Sbjct: 810 CADSPCRNRATCQDSPQGP-RCLCPTGYTGGSC--QTLMDLCAQKPCPRNSHCLQTGPSF 866
Query: 2067 -CECNLDYEGDGITCTVVDFCKQDNGGCAKVA---------------RCSQKGTKVSCSC 2110
C C + G C C K A C G C C
Sbjct: 867 HCLCLQGWTG--------PLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
Query: 2111 QKGYKGDGHSCTE-IDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL 2169
G++G C + ++PC + C ATC M P + C+C Y DG NC E
Sbjct: 919 PPGFQGS--LCQDHVNPCE---SRPCQNGATC-MAQPSGYLCQCAPGY--DGQNCSKE-- 968
Query: 2170 PIDRCLQDNGQCHADAKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREACANE 2223
+D C + CH C G FH P G L + + C ++
Sbjct: 969 -LDAC--QSQPCHNHGTCT------PKPGGFHCACPPGFVGLRCEGDVDECLDQ 1013
Score = 86.7 bits (213), Expect = 3e-16
Identities = 70/225 (31%), Positives = 94/225 (41%), Gaps = 31/225 (13%)
Query: 1336 CCAGFFGPQCQPCPGN-AQNVCFGNGICLDGVNGTGVCECGEGFSGTAC-----ETCTEG 1389
C GF GP C+ P N + C G C DG++ T C C E ++G C E T+G
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQG 322
Query: 1390 KYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTN 1449
HC +C Q G C C GW G C+ +D TC + C+ +
Sbjct: 323 P--PHCRNGGTC------QNSAGSFHCVCVSGWGGTSCEE-NLDDCIAATCAPGSTCI-D 372
Query: 1450 SDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTP--GRRVCTCKAGYTGD 1507
G+ SC C G G +C + C + C A C T P G +C C+ GY+G
Sbjct: 373 RVGSFSCLCPPG--RTGLLCHLEDMC--LSQPCHGDAQCS-TNPLTGSTLCLCQPGYSGP 427
Query: 1508 GIVC-LEINPCLENHGG---CDKNAECTQTGPNQAACNCLPAYTG 1548
C +++ CL G C+ C T P C C P YTG
Sbjct: 428 --TCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCLCPPGYTG 469
Score = 85.9 bits (211), Expect = 5e-16
Identities = 76/270 (28%), Positives = 101/270 (37%), Gaps = 39/270 (14%)
Query: 100 CCPGRWGPDCIECPGGAGS-PCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADD-NLFG 157
C PG GPDC P S C G+C +G++ TC C E + G C D+ G
Sbjct: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQG 322
Query: 158 PSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDE 217
P +C +G G C C S + G C++ + +C A C S C +
Sbjct: 323 PP-----HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC---IDRV 374
Query: 218 NKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHS--CTCQEGYRG----- 270
C C P G C + CL + CH A C+ P S C CQ GY G
Sbjct: 375 GSFSCLCPPG--RTGLLCHLEDMCLSQPCHGDAQCS-TNPLTGSTLCLCQPGYSGPTCHQ 431
Query: 271 DGQVCLPV----DPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDIC 326
D CL PC+ + G+C + PG +C C Y G C
Sbjct: 432 DLDECLMAQQGPSPCE-HGGSC--------LNTPGSFNCLCPPGY----TGSRCEADHNE 478
Query: 327 KSDNPCHRNANCTTVAPGRTECICQKGYVG 356
PCH + C + C+C G G
Sbjct: 479 CLSQPCHPGSTCLDLL-ATFHCLCPPGLEG 507
Score = 83.2 bits (204), Expect = 3e-15
Identities = 70/259 (27%), Positives = 89/259 (34%), Gaps = 45/259 (17%)
Query: 1949 RCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE-------------------CKCN 1989
+C G+ G CQ PD PC N +C + S C C
Sbjct: 52 QCAPGFLGETCQF----PD-PCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCL 106
Query: 1990 TGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPA 2049
GF G C+ + C P CS G+C +G QC C GWTG C + A
Sbjct: 107 PGFTGERCQ----AKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSA 162
Query: 2050 VCTPPCSAHATCKENN---TCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKV 2106
PC C C C +EG V + C QD G C K C
Sbjct: 163 ---NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE-CFQDPGPCPKGTSCHNTLGSF 218
Query: 2107 SCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGK----HKCECKSHYVGDGL 2162
C C G +G PC GC TC++ P K H C C ++G
Sbjct: 219 QCLCPVGQEGP-RCELRAGPCPP---RGCSNGGTCQLM-PEKDSTFHLCLCPPGFIGPDC 273
Query: 2163 NCEPEQLPIDRCLQDNGQC 2181
P+ +C Q+ G C
Sbjct: 274 EVNPDNCVSHQC-QNGGTC 291
Score = 82.4 bits (202), Expect = 5e-15
Identities = 70/284 (24%), Positives = 98/284 (34%), Gaps = 50/284 (17%)
Query: 100 CCPGRWGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGP 158
C PG G C +E A +PC C + + G C C GF GT CE D+ P
Sbjct: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGF-QCICLPGFSGTRCEEDIDECRSSP 559
Query: 159 SCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDEN 218
C +G G C+C + GP+C + EC + CP + C +
Sbjct: 560 -------CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC---LDLPG 609
Query: 219 KLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPV 278
C C + G+ C+ + C +C P C ++ +C C +G G P
Sbjct: 610 AFFCLCPSGF--TGQLCE-VPLCAPNLCQPKQICKD-QKDKANCLCPDGSPG---CAPPE 662
Query: 279 DPCQINFGNCPTKSTVCK--------------------------YDGPGQSHCECKEHYQ 312
D C + G+C S VC Y P +C C Y
Sbjct: 663 DNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY- 721
Query: 313 NFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
G CS PC +C +PG C C + G
Sbjct: 722 ---TGPTCSEEMTACHSGPCLNGGSCNP-SPGGYYCTCPPSHTG 761
Score = 82.0 bits (201), Expect = 7e-15
Identities = 82/309 (26%), Positives = 110/309 (35%), Gaps = 58/309 (18%)
Query: 107 PDCIECPGGAGSPCNGRGSCAEGMEGNG----------TCSCQEGFGGTACETCADDNLF 156
P C PG G C R C+ NG C C GF G ACE ++
Sbjct: 141 PQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQ 200
Query: 157 GPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTED 216
P C G G C C GP+C+ C C C E
Sbjct: 201 DPG-----PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEK 255
Query: 217 ENKLE-CKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVC 275
++ C C P + G +P N C+ C C G + ++C C E + G
Sbjct: 256 DSTFHLCLCPPGFIGPDCEVNPDN-CVSHQCQNGGTCQD-GLDTYTCLCPETWTG-WDCS 312
Query: 276 LPVDPCQI-------NFGNCPTKS----TVCKYDGPGQSHCE----------------CK 308
VD C+ N G C + VC G G + CE C
Sbjct: 313 EDVDECETQGPPHCRNGGTCQNSAGSFHCVC-VSGWGGTSCEENLDDCIAATCAPGSTCI 371
Query: 309 EHYQNFV-------PGVGCSMTDICKSDNPCHRNANCTT-VAPGRTECICQKGYVGDGLT 360
+ +F G+ C + D+C S PCH +A C+T G T C+CQ GY G T
Sbjct: 372 DRVGSFSCLCPPGRTGLLCHLEDMCLS-QPCHGDAQCSTNPLTGSTLCLCQPGY--SGPT 428
Query: 361 CYGNIMERL 369
C+ ++ E L
Sbjct: 429 CHQDLDECL 437
Score = 82.0 bits (201), Expect = 7e-15
Identities = 79/281 (28%), Positives = 112/281 (39%), Gaps = 48/281 (17%)
Query: 728 CCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKY--- 784
C G+ G C +NPC G C + C C GF+G C+ D N+
Sbjct: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATY-PQIQCHCPPGFEGHACE--RDVNECFQD 201
Query: 785 -GPRCNKKCLCVHGT-CNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHAT 842
GP C GT C+N + S CL C G G C+ + C P + C T
Sbjct: 202 PGP-------CPKGTSCHNTLGS-FQCL---CPVGQEGPRCELRAGPCPP--RGCSNGGT 248
Query: 843 CEYSNGTAS----CICKAGYEGDGTLCSEMDPCTGLTPGGC----SRNAECIKTGTGTHT 894
C+ S C+C G+ G P + P C +N + G T+T
Sbjct: 249 CQLMPEKDSTFHLCLCPPGFIG---------PDCEVNPDNCVSHQCQNGGTCQDGLDTYT 299
Query: 895 CVCQQGWTGNGRDCSE-INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP 953
C+C + WT G DCSE ++ C C + +C G C C G+ G + E
Sbjct: 300 CLCPETWT--GWDCSEDVDECETQGPPHCRNGGTC-QNSAGSFHCVCVSGWGGTSCE-EN 355
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLCY 994
+ C+ T C P ++C G +SC+C G G LC+
Sbjct: 356 LDDCIAAT--CAPGSTC-IDRVGSFSCLCPPG--RTGLLCH 391
Score = 80.9 bits (198), Expect = 2e-14
Identities = 80/294 (27%), Positives = 113/294 (38%), Gaps = 66/294 (22%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQC-----QFC 778
C G G C N+C S PC + C D L G CIC GF G++C +
Sbjct: 501 CPPGLEGQLCEVETNECA---SAPCLNHADCHDLLNGF-QCICLPGFSGTRCEEDIDECR 556
Query: 779 SDPNKYGPRCNKK-----CLCVHG----TCNNRID---SDGACLTGTCRD---------- 816
S P G +C + C C+ G C +D SD + +C D
Sbjct: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
Query: 817 -GSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLT 875
G G+LC + C P C C+ A+C+C G G C+ +
Sbjct: 617 SGFTGQLC--EVPLCAP--NLCQPKQICKDQKDKANCLCPDGSPG----CAPPEDNCTCH 668
Query: 876 PGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDC-SEINNCLLPSAGGCHDNASCLYVGPG 934
G C R+ +CVC GWT G +C +E+ C+ + C +C Y P
Sbjct: 669 HGHCQRS-----------SCVCDVGWT--GPECEAELGGCI---SAPCAHGGTC-YPQPS 711
Query: 935 QNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
C C G+ G E +T+C +G C SC + S G + C C + G
Sbjct: 712 GYNCTCPTGYTGPTCS-EEMTAC--HSGPCLNGGSC-NPSPGGYYCTCPPSHTG 761
Score = 79.0 bits (193), Expect = 6e-14
Identities = 75/273 (27%), Positives = 98/273 (35%), Gaps = 38/273 (13%)
Query: 1337 CAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCD 1396
C P+ C G+ C G CL G G C+C GF G C+ + C
Sbjct: 17 CVSVVRPRGLLC-GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ------FPDPCQ 69
Query: 1397 QACSCVHGRCNQ----GPLGDGS----------CDCDVGWRGVHCDNATTEDNCNGT-CH 1441
A C +G Q PLG S C C G+ G C A ED C + C
Sbjct: 70 NAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERC-QAKLEDPCPPSFCS 128
Query: 1442 TSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCK 1501
C + G C C G+ G C + C S C C T P + C C
Sbjct: 129 KRGRCHIQASGRPQCSCMPGWTGEQ--CQLRDFC--SANPCVNGGVCLATYP-QIQCHCP 183
Query: 1502 AGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTL-INVCL 1560
G+ G ++N C ++ G C K C T + CL +G C L C
Sbjct: 184 PGFEGHACE-RDVNECFQDPGPCPKGTSCHNT---LGSFQCLCPVGQEGPRCELRAGPCP 239
Query: 1561 TKNGGCSEFAICNHTGQVERT---CTCKPNYIG 1590
+ GCS C + + T C C P +IG
Sbjct: 240 PR--GCSNGGTCQLMPEKDSTFHLCLCPPGFIG 270
Score = 78.2 bits (191), Expect = 1e-13
Identities = 71/272 (26%), Positives = 106/272 (38%), Gaps = 35/272 (12%)
Query: 1336 CCAGFFGPQC-QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
C G+ GP C + C G C G C C +G C+T T+ +
Sbjct: 717 CPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY-YCTCPPSHTGPQCQTSTD-----Y 770
Query: 1395 CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTA 1454
C A G C P G SC C +G++G C+ + C A C + G
Sbjct: 771 CVSAPCFNGGTCVNRP-GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQG-P 828
Query: 1455 SCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
C C G+ G G+ T ++ C + C + C +T P C C G+TG + L +
Sbjct: 829 RCLCPTGYTG-GSCQTLMDLC--AQKPCPRNSHCLQTGPSFH-CLCLQGWTGP-LCNLPL 883
Query: 1515 NPC--------LENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVC-TLINVCLTKNGG 1565
+ C ++ C C +GP+ C+C P + G +C +N C ++
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSY-FCHCPPGF--QGSLCQDHVNPC--ESRP 938
Query: 1566 CSEFAIC--NHTGQVERTCTCKPNYIGDGFTC 1595
C A C +G + C C P Y DG C
Sbjct: 939 CQNGATCMAQPSGYL---CQCAPGY--DGQNC 965
Score = 77.8 bits (190), Expect = 1e-13
Identities = 67/245 (27%), Positives = 83/245 (33%), Gaps = 57/245 (23%)
Query: 99 RCCPGRWGPDCI-ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
+C PG G +C E PC+ G+C G C+C GF G CE D+ L
Sbjct: 955 QCAPGYDGQNCSKELDACQSQPCHNHGTCTP-KPGGFHCACPPGFVGLRCEGDVDECLDQ 1013
Query: 158 P-------SCSSVCNCVHGVCNSGLDGD-----------------GTCE----------- 182
P +C S+ N + C G G GTCE
Sbjct: 1014 PCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
Query: 183 -CYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPC 241
C + GP C P C C C PS + C CL Y G D + P
Sbjct: 1074 HCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGP----DCLTPP 1129
Query: 242 LRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPG 301
K C P + C Y G SC+ G G G C +CP S + PG
Sbjct: 1130 APKGCGPPSPCLYNG----SCSETTGLGGPGFRC-----------SCPHSSPGPRCQKPG 1174
Query: 302 QSHCE 306
CE
Sbjct: 1175 AKGCE 1179
Score = 76.3 bits (186), Expect = 4e-13
Identities = 80/312 (25%), Positives = 114/312 (36%), Gaps = 56/312 (17%)
Query: 1962 CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCD 2021
C P+ PC N G CL G C+C GF G C+ P C + C
Sbjct: 28 CGSFPE-PCANGGTCLSLSLGQGTCQCAPGFLGETCQF-----------PDPCQNAQLCQ 75
Query: 2022 DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCT 2081
+G G C QA+LPA P S+ + + C C + G+
Sbjct: 76 NG----GSC-------------QALLPAPLGLP-SSPSPLTPSFLCTCLPGFTGERCQAK 117
Query: 2082 VVDFCKQDNGGCAKVARCS-QKGTKVSCSCQKGYKGDGHSCTEIDPCADG--LNGGCHEH 2138
+ D C C+K RC Q + CSC G+ G+ C D C+ +NGG
Sbjct: 118 LEDPCPPSF--CSKRGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCSANPCVNGG---- 169
Query: 2139 ATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVG 2198
C T P + +C C + G CE + ++ C QD G C C T+G
Sbjct: 170 -VCLATYP-QIQCHCPPGFEGHA--CERD---VNECFQDPGPCPKGTSC------HNTLG 216
Query: 2199 VFHLRSPLGQYKLTFDKAREACANEAATMATYNQLSYAQKAKYH--LCSAGWLETGRVAY 2256
F P+GQ + C + QL + + +H LC G++
Sbjct: 217 SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN 276
Query: 2257 PTAFASQNCGSG 2268
P S C +G
Sbjct: 277 PDNCVSHQCQNG 288
Score = 75.5 bits (184), Expect = 6e-13
Identities = 84/308 (27%), Positives = 108/308 (35%), Gaps = 75/308 (24%)
Query: 1950 CCKGYFGRDCQACPGG-PDAPCNNRGVCL---DQYSATGECKCNTGFNGTACEMCWPGRF 2005
C G G C+ G P C+N G C ++ S C C GF G CE+
Sbjct: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV------ 275
Query: 2006 GPD-CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPP-CSAHATCKE 2063
PD C+ C + G C DG+ + CLC WTG C PP C TC+
Sbjct: 276 NPDNCVSHQCQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 334
Query: 2064 N--------------NTCECNLD-------------------------YEGDGITCTVVD 2084
+ +CE NLD G+ C + D
Sbjct: 335 SAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLED 394
Query: 2085 FCKQDNGGCAKVARCSQKGTKVS--CSCQKGYKGDGHSC-TEIDPCADGLNG--GCHEHA 2139
C C A+CS S C CQ GY G +C ++D C G C
Sbjct: 395 MCLSQ--PCHGDAQCSTNPLTGSTLCLCQPGYSGP--TCHQDLDECLMAQQGPSPCEHGG 450
Query: 2140 TCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTTVGV 2199
+C T PG C C Y G CE + + CL CH + C+DL +
Sbjct: 451 SCLNT-PGSFNCLCPPGYTGS--RCEADH---NECLSQ--PCHPGSTCLDL------LAT 496
Query: 2200 FHLRSPLG 2207
FH P G
Sbjct: 497 FHCLCPPG 504
Score = 74.7 bits (182), Expect = 1e-12
Identities = 72/258 (27%), Positives = 104/258 (40%), Gaps = 40/258 (15%)
Query: 1346 QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTAC----ETCTEGKYGIHCDQACSC 1401
QPC G+AQ C N + G+ +C C G+SG C + C + G C
Sbjct: 399 QPCHGDAQ--CSTNPL-----TGSTLCLCQPGYSGPTCHQDLDECLMAQQG-----PSPC 446
Query: 1402 VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAG 1461
HG G +C C G+ G C+ A + + CH + CL + T C C G
Sbjct: 447 EHGGSCLNTPGSFNCLCPPGYTGSRCE-ADHNECLSQPCHPGSTCL-DLLATFHCLCPPG 504
Query: 1462 FQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-INPCLEN 1520
+G +C + E ++ C ADC G + C C G++G C E I+ C
Sbjct: 505 LEGQ--LC-EVETNECASAPCLNHADCHDLLNGFQ-CICLPGFSGTR--CEEDIDEC--R 556
Query: 1521 HGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK----NGGCSE-----FAI 1571
C +C Q P C CLP + G + T ++ CL+ C + F +
Sbjct: 557 SSPCANGGQC-QDQPGAFHCKCLPGFEGP-RCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
Query: 1572 C--NHTGQVERTCTCKPN 1587
C TGQ+ C PN
Sbjct: 615 CPSGFTGQLCEVPLCAPN 632
Score = 74.3 bits (181), Expect = 1e-12
Identities = 83/324 (25%), Positives = 111/324 (34%), Gaps = 101/324 (31%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE------- 1998
C + + G DC C C N G C + + + C C +G+ GT+CE
Sbjct: 302 CPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS-AGSFHCVCVSGWGGTSCEENLDDCI 360
Query: 1999 -------------------MCWPGRFG------PDCLPCGCSDHGQCDDG-ITGSGQCLC 2032
+C PGR G CL C QC +TGS CLC
Sbjct: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC 420
Query: 2033 ETGWTGPSC--DTQAVLPAVCTP-PCSAHATCKE---NNTCECNLDYEGD---------- 2076
+ G++GP+C D L A P PC +C + C C Y G
Sbjct: 421 QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL 480
Query: 2077 ------GITCTVV--------------DFCKQDNGGCAKV-----ARCSQKGTKVSCSCQ 2111
G TC + C+ + CA A C C C
Sbjct: 481 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 540
Query: 2112 KGYKG-----DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
G+ G D C PCA+G G C + PG C+C + +G C+
Sbjct: 541 PGFSGTRCEEDIDECRS-SPCANG--GQCQDQ-------PGAFHCKCLPGF--EGPRCQT 588
Query: 2167 EQLPIDRCLQDNGQCHADAKCVDL 2190
E +D CL D C A C+DL
Sbjct: 589 E---VDECLSD--PCPVGASCLDL 607
Score = 74.3 bits (181), Expect = 1e-12
Identities = 94/401 (23%), Positives = 131/401 (32%), Gaps = 161/401 (40%)
Query: 1336 CCAGFFGPQCQ---------PCPGNAQ------------------------------NVC 1356
C GF G +C+ PC Q + C
Sbjct: 539 CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
Query: 1357 FGNGICLDGVNGTGVCECGEGFSGTACET-------------CTEGKYGIHC-------- 1395
CLD + G C C GF+G CE C + K +C
Sbjct: 599 PVGASCLD-LPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG 657
Query: 1396 ----DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCD----------------------- 1428
+ C+C HG C + SC CDVGW G C+
Sbjct: 658 CAPPEDNCTCHHGHCQR-----SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG 712
Query: 1429 -NAT-----TEDNCN--------------GTC--------------HTSANCLTNSD--- 1451
N T T C+ G+C HT C T++D
Sbjct: 713 YNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCV 772
Query: 1452 --------------GTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRV 1497
GT SC CA GFQ G C ++ C +A C+ + G R
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQ--GPRCEGKLRPSCADSPCRNRATCQDSPQGPR- 829
Query: 1498 CTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTL-I 1556
C C GYTG L ++ C + C +N+ C QTGP+ C CL +T G +C L +
Sbjct: 830 CLCPTGYTGGSCQTL-MDLCAQK--PCPRNSHCLQTGPS-FHCLCLQGWT--GPLCNLPL 883
Query: 1557 NVC--LTKNGGCSEFAICNHTGQVERT-----CTCKPNYIG 1590
+ C + G ++C++ G + C C P + G
Sbjct: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG 924
Score = 73.6 bits (179), Expect = 2e-12
Identities = 75/269 (27%), Positives = 99/269 (36%), Gaps = 49/269 (18%)
Query: 1949 RCCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE------ 1998
+C G+ G CQ C P C CLD A C C +GF G CE
Sbjct: 576 KCLPGFEGPRCQTEVDECLSDP---CPVGASCLDLPGAFF-CLCPSGFTGQLCEVPLCAP 631
Query: 1999 -MCWPGRFGPD------CLPC-----GCS---DHGQCDDGITGSGQCLCETGWTGPSCDT 2043
+C P + D CL C GC+ D+ C G C+C+ GWTGP C
Sbjct: 632 NLCQPKQICKDQKDKANCL-CPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC-- 688
Query: 2044 QAVLPAVCTPPCSAHATC---KENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCS 2100
+A L + PC+ TC C C Y G TC+ + +G C C+
Sbjct: 689 EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP--TCS-EEMTACHSGPCLNGGSCN 745
Query: 2101 QKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGD 2160
C+C + G T D C ++ C TC + PG C C +
Sbjct: 746 PSPGGYYCTCPPSHTGP-QCQTSTDYC---VSAPCFNGGTC-VNRPGTFSCLCAMGF--Q 798
Query: 2161 GLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
G CE + P C + C A C D
Sbjct: 799 GPRCEGKLRP--SCA--DSPCRNRATCQD 823
Score = 72.8 bits (177), Expect = 4e-12
Identities = 64/255 (25%), Positives = 97/255 (38%), Gaps = 25/255 (9%)
Query: 114 GGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTAC---ETCADDNLF--GPSCSSVCNCVH 168
G PC G+C G GTC C GF G C + C + L G SC ++
Sbjct: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPL 88
Query: 169 GVCN--SGLDGDGTCECYSAYTGPKCDKPIPE-CAALLCPENSRCSPSTEDENKLECKCL 225
G+ + S L C C +TG +C + + C C + RC + + +C C+
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRC--HIQASGRPQCSCM 146
Query: 226 PNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVC-LPVDPCQIN 284
P + G+ C + C C C P + C C G+ +G C V+ C +
Sbjct: 147 PGWTGE--QCQLRDFCSANPCVNGGVCLATYP-QIQCHCPPGF--EGHACERDVNECFQD 201
Query: 285 FGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPG 344
G CP K T C ++ G C C + G C + C C +
Sbjct: 202 PGPCP-KGTSC-HNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMPEK 255
Query: 345 RTE---CICQKGYVG 356
+ C+C G++G
Sbjct: 256 DSTFHLCLCPPGFIG 270
Score = 71.6 bits (174), Expect = 9e-12
Identities = 73/281 (25%), Positives = 96/281 (34%), Gaps = 45/281 (16%)
Query: 1333 TRECCAGFFGPQCQ-PCPGNAQNVCFGNGICL-------------DGVNGTGVCECGEGF 1378
T +C GF G CQ P P +C G C + + +C C GF
Sbjct: 50 TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGF 109
Query: 1379 SGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNG 1438
+G C+ E C + GRC+ G C C GW G C D C+
Sbjct: 110 TGERCQAKLEDP----CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQ---LRDFCSA 162
Query: 1439 T-CHTSANCLTNSDGTASCKCAAGFQGNGTICTA-INACEISNGGCSAKADCKRTTPGRR 1496
C CL C C GF+G+ C +N C G C C T G
Sbjct: 163 NPCVNGGVCLATYP-QIQCHCPPGFEGHA--CERDVNECFQDPGPCPKGTSCHNTL-GSF 218
Query: 1497 VCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAA----CNCLPAYTGDGKV 1552
C C G G L PC GC C Q P + + C C P + G
Sbjct: 219 QCLCPVGQEGPRCE-LRAGPCPPR--GCSNGGTC-QLMPEKDSTFHLCLCPPGFIGPDCE 274
Query: 1553 CTLINVCLT---KNGGCSEFAICNHTGQVERTCTCKPNYIG 1590
N C++ +NGG + + + TC C + G
Sbjct: 275 VNPDN-CVSHQCQNGGTCQDGLDTY------TCLCPETWTG 308
Score = 70.1 bits (170), Expect = 3e-11
Identities = 82/301 (27%), Positives = 106/301 (35%), Gaps = 56/301 (18%)
Query: 1323 CQP--KCVRTVITRECCA--GFFGPQCQPCPGNAQNV-CFGNGICLDGVNGTGVCECGEG 1377
C P C+ + T C G G C+ + C + C D +NG C C G
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ-CICLPG 542
Query: 1378 FSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC- 1436
FSGT CE + C + G+C P G C C G+ G C T D C
Sbjct: 543 FSGTRCEEDID-----ECRSSPCANGGQCQDQP-GAFHCKCLPGFEGPRCQ--TEVDECL 594
Query: 1437 NGTCHTSANCLTNSDGTASCKCAAGFQGN--------------GTIC-----TAINACEI 1477
+ C A+CL + G C C +GF G IC A C
Sbjct: 595 SDPCPVGASCL-DLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPD 653
Query: 1478 SNGGCSAKAD---CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG 1534
+ GC+ D C R C C G+TG C GGC +A C G
Sbjct: 654 GSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGP--------ECEAELGGC-ISAPCAHGG 704
Query: 1535 -----PNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI 1589
P+ C C YT G C+ + +G C CN CTC P++
Sbjct: 705 TCYPQPSGYNCTCPTGYT--GPTCS-EEMTACHSGPCLNGGSCN-PSPGGYYCTCPPSHT 760
Query: 1590 G 1590
G
Sbjct: 761 G 761
Score = 67.4 bits (163), Expect = 2e-10
Identities = 79/313 (25%), Positives = 115/313 (36%), Gaps = 74/313 (23%)
Query: 1336 CCAGFFGPQCQPC--PGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
C GF GP+C+ P A + C C D G C C G++G +C+T +
Sbjct: 793 CAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR-CLCPTGYTGGSCQTLMDLCAQK 851
Query: 1394 HCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTED---------NCNGTCHTSA 1444
C + C+ GP C C GW G C+ + + + CH
Sbjct: 852 PCPRNSHCLQ----TGP--SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
Query: 1445 NCLTNSDGTASCKCAAGFQGNGTICTA-INACEISNGGCSAKADCKRTTPGRRVCTCKAG 1503
C+ +S + C C GFQG+ +C +N CE + C A C P +C C G
Sbjct: 906 LCV-DSGPSYFCHCPPGFQGS--LCQDHVNPCE--SRPCQNGATCM-AQPSGYLCQCAPG 959
Query: 1504 YTGDG----IVCLEINPCLENHGGCDK--------------------------NAECTQT 1533
Y G + + PC NHG C + C T
Sbjct: 960 YDGQNCSKELDACQSQPC-HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018
Query: 1534 GP-------NQAACNCLPAYTGDGKVCTL-INVCLTK---NGGCSEFAICNHTGQVERTC 1582
G N C CLP +T G+ C + I+ C ++ +GG E + G + C
Sbjct: 1019 GTAACHSLANAFYCQCLPGHT--GQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFI---C 1073
Query: 1583 TCKPNYIGDGFTC 1595
C + +G TC
Sbjct: 1074 HCPKGF--EGPTC 1084
Score = 65.9 bits (159), Expect = 5e-10
Identities = 90/362 (24%), Positives = 125/362 (34%), Gaps = 69/362 (19%)
Query: 1315 GRRTLFIGCQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCEC 1374
GR + +P+C C G+ G QCQ + N C G+CL C C
Sbjct: 131 GRCHIQASGRPQC-------SCMPGWTGEQCQLRDFCSANPCVNGGVCL-ATYPQIQCHC 182
Query: 1375 GEGFSGTACE----------------------------TCTEGKYGIHCD-QACSCVHGR 1405
GF G ACE C G+ G C+ +A C
Sbjct: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
Query: 1406 CNQG------PLGDGS---CDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASC 1456
C+ G P D + C C G+ G C+ DNC H N T DG +
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE--VNPDNC--VSHQCQNGGTCQDGLDTY 298
Query: 1457 KCAAGFQGNGTICTA-INACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-I 1514
C G C+ ++ CE + + G C C +G+ G C E +
Sbjct: 299 TCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS--CEENL 356
Query: 1515 NPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNH 1574
+ C+ C + C +C C P T G +C L ++CL++ C A C+
Sbjct: 357 DDCIA--ATCAPGSTCIDR-VGSFSCLCPPGRT--GLLCHLEDMCLSQ--PCHGDAQCST 409
Query: 1575 TGQVERT-CTCKPNYIGDGFTCRGSIYQELPKNPKTSQYFFQLQEHFVKDLVGPGPFTVF 1633
T C C+P Y G TC + + L S EH L PG F
Sbjct: 410 NPLTGSTLCLCQPGYSGP--TCHQDLDECLMAQQGPSPC-----EHGGSCLNTPGSFNCL 462
Query: 1634 AP 1635
P
Sbjct: 463 CP 464
Score = 53.5 bits (127), Expect = 3e-06
Identities = 66/248 (26%), Positives = 87/248 (35%), Gaps = 35/248 (14%)
Query: 719 CNATVKIP-----KCCKGFYGPDCN-QCPGGFSNPCSGNGQCADSL--GGNGTCICEEGF 770
C AT P C KGF GP C+ + P + C G C S G C C G+
Sbjct: 1061 CEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY 1120
Query: 771 QGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSAC 830
G C P GP CL +G+C+ G +C S G C K +
Sbjct: 1121 GGPDCLTPPAPKGCGPP--SPCL-YNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAK- 1176
Query: 831 GPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPG--GCSRNAEC--- 885
CE +G +C AG G G D G+ GC ++ C
Sbjct: 1177 -----------GCEGRSGDGAC--DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLL 1223
Query: 886 IKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR 945
+ G C ++ +G DC C CHD+ + G N EC G+
Sbjct: 1224 FRDGQCHPQCDSEE-CLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAEC--GWD 1280
Query: 946 GNGIDCEP 953
G DC P
Sbjct: 1281 GG--DCRP 1286
Score = 48.9 bits (115), Expect = 6e-05
Identities = 73/257 (28%), Positives = 91/257 (35%), Gaps = 54/257 (21%)
Query: 675 GTCVSCS---LVYWSRCPANSE--------PTALFTHRCVYSGR-FGSLKSGCARYCNAT 722
GTC + + L + CP E P+ F H C + G S K G C
Sbjct: 1059 GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF-HHCHHGGLCLPSPKPGFPPRC--- 1114
Query: 723 VKIPKCCKGFYGPDCNQCPG----GFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFC 778
C G+ GPDC P G +PC NG C+++ G G GF+ C
Sbjct: 1115 ----ACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGG-----PGFR------C 1159
Query: 779 SDPNKY-GPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFC 837
S P+ GPRC K C R DGAC G G D P+ + C
Sbjct: 1160 SCPHSSPGPRCQKPGA---KGCEGR-SGDGACDAGCSGPGGNWDGGDCSLGVPDPW-KGC 1214
Query: 838 HIHATCEYSNGTASCICKAGYEG---DGTLCSEMDPCTGLTPGGCS---RNAECIKTGTG 891
H+ C C + E DG C CT C N C K G
Sbjct: 1215 PSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEK---G 1271
Query: 892 THTCVCQQGWTGNGRDC 908
+T C GW +G DC
Sbjct: 1272 CNTAEC--GW--DGGDC 1284
Score = 48.1 bits (113), Expect = 1e-04
Identities = 62/238 (26%), Positives = 79/238 (33%), Gaps = 39/238 (16%)
Query: 1947 IPRCCKGYFGRDCQ-ACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
I C KG+ G C P C++ G+CL +C C G
Sbjct: 1072 ICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRC----------ACLSGYG 1121
Query: 2006 GPDCL----PCGCSDHGQCDDGITGSGQCLCETGWTGP----SCDTQAVLPAVCTPPCSA 2057
GPDCL P GC C +G C TG GP SC + P P
Sbjct: 1122 GPDCLTPPAPKGCGPPSPC----LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG 1177
Query: 2058 HATCKENNTCECNLDYEG---DGITCT--VVDFCKQDNGGCAKVARCSQKGTKVSCSCQK 2112
+ C+ G DG C+ V D K GC +RC C Q
Sbjct: 1178 CEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWK----GCPSHSRCWLLFRDGQCHPQC 1233
Query: 2113 GYKG---DGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPE 2167
+ DG+ C C + CH+H G + EC DG +C PE
Sbjct: 1234 DSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECG----WDGGDCRPE 1287
Score = 42.0 bits (97), Expect = 0.008
Identities = 29/122 (23%), Positives = 46/122 (37%), Gaps = 16/122 (13%)
Query: 1482 CSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPC-----LENHGGCDKNAECTQTGPN 1536
C+ C + G+ C C G+ G+ C +PC +N G C P+
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGE--TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
Query: 1537 QAA-------CNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI 1589
+ C CLP +TG+ L + C CS+ C+ C+C P +
Sbjct: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPC--PPSFCSKRGRCHIQASGRPQCSCMPGWT 150
Query: 1590 GD 1591
G+
Sbjct: 151 GE 152
Score = 42.0 bits (97), Expect = 0.008
Identities = 60/241 (24%), Positives = 81/241 (33%), Gaps = 53/241 (21%)
Query: 1335 ECCAGFFGPQCQ----PCPGNAQNVCFGNGICLDGVNGTG---VCECGEGFSGTACETCT 1387
+C G G C+ PC CF G C + G+ +C C +GF G C
Sbjct: 1033 QCLPGHTGQWCEVEIDPCHSQP---CFHGGTC-EATAGSPLGFICHCPKGFEGPTCSHRA 1088
Query: 1388 EGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCL 1447
HC C+ + P C C G+ G C C + CL
Sbjct: 1089 PSCGFHHCHHGGLCLP---SPKPGFPPRCACLSGYGGPDCLTPPAPKGCG----PPSPCL 1141
Query: 1448 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD 1507
N SC G G G C +C S+ G C++ PG + C G +GD
Sbjct: 1142 YN----GSCSETTGLGGPGFRC----SCPHSSPG----PRCQK--PGAKGC---EGRSGD 1184
Query: 1508 GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVC--LTKNGG 1565
G CD A C+ G N +C K C + C L ++G
Sbjct: 1185 --------------GACD--AGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQ 1228
Query: 1566 C 1566
C
Sbjct: 1229 C 1229
Score = 41.2 bits (95), Expect = 0.013
Identities = 37/149 (24%), Positives = 50/149 (33%), Gaps = 24/149 (16%)
Query: 853 ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTG--------- 903
+C + G LC G P C+ C+ G TC C G+ G
Sbjct: 16 LCVSVVRPRGLLC-------GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPC 68
Query: 904 -NGRDCSEINNC--LLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQ 960
N + C +C LLP+ G + S L C C GF G + C
Sbjct: 69 QNAQLCQNGGSCQALLPAPLGLPSSPSPL---TPSFLCTCLPGFTGERCQAKLEDPC--P 123
Query: 961 TGKCHPLASCQSTSSGVWSCVCQEGYEGD 989
C C +SG C C G+ G+
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
>gi|122937400 odz, odd Oz/ten-m homolog 3 [Homo sapiens]
Length = 2699
Score = 100 bits (248), Expect = 2e-20
Identities = 65/207 (31%), Positives = 85/207 (41%), Gaps = 50/207 (24%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM---------- 1999
C GY G C+ D C+N GVC+ GEC C+ G+ G+ CE+
Sbjct: 600 CNSGYKGESCEEADC-IDPGCSNHGVCIH-----GECHCSPGWGGSNCEILKTMCPDQCS 653
Query: 2000 -------------CWPGRFGPDC----LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 2042
C P GPDC C HG C G C CE GWTGP+C+
Sbjct: 654 GHGTYLQESGSCTCDPNWTGPDCSNEICSVDCGSHGVCM-----GGTCRCEEGWTGPACN 708
Query: 2043 TQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
+A C P C+ H TCK+ CEC+ + G+ T ++ C G C RC+
Sbjct: 709 QRA-----CHPRCAEHGTCKDGK-CECSQGWNGEHCT---IEGCP---GLCNSNGRCTLD 756
Query: 2103 GTKVSCSCQKGYKGDGHSCTEIDPCAD 2129
C CQ G++G G C D
Sbjct: 757 QNGWHCVCQPGWRGAGCDVAMETLCTD 783
Score = 99.8 bits (247), Expect = 3e-20
Identities = 69/237 (29%), Positives = 100/237 (42%), Gaps = 48/237 (20%)
Query: 1950 CCKGYFGRDCQA-CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G +C D C RG+C+ G C CN+G+ G +CE D
Sbjct: 566 CFSGWKGTECDVPTTQCIDPQCGGRGICI-----MGSCACNSGYKGESCEEA-------D 613
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHAT-CKENNTC 2067
C+ GCS+HG C G +C C GW G +C+ +L +C CS H T +E+ +C
Sbjct: 614 CIDPGCSNHGVCIHG-----ECHCSPGWGGSNCE---ILKTMCPDQCSGHGTYLQESGSC 665
Query: 2068 ECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPC 2127
C+ ++ G + + +G C GT C C++G+ G + P
Sbjct: 666 TCDPNWTGPDCSNEICSVDCGSHGVC-------MGGT---CRCEEGWTGPACNQRACHP- 714
Query: 2128 ADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHAD 2184
C EH TCK KCEC + G+ +C E P NG+C D
Sbjct: 715 ------RCAEHGTCK-----DGKCECSQGWNGE--HCTIEGCP--GLCNSNGRCTLD 756
Score = 97.4 bits (241), Expect = 2e-19
Identities = 86/306 (28%), Positives = 119/306 (38%), Gaps = 81/306 (26%)
Query: 715 CARYCNATVKIPK----CCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEE 768
C R C+ + C GF GPDC++ CP CSGNGQ + G C+C
Sbjct: 518 CPRNCHGNGECVSGTCHCFPGFLGPDCSRAACPV----LCSGNGQYS-----KGRCLCFS 568
Query: 769 GFQGSQCQF----CSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCD 824
G++G++C C DP +C + +C+ G+C C G G C+
Sbjct: 569 GWKGTECDVPTTQCIDP-----QCGGRGICIMGSC-------------ACNSGYKGESCE 610
Query: 825 KQTS---ACGPYVQFCHIHATCEYSNGTASC-----ICKAGYEGDGTLCSEMDPCT---G 873
+ C + H C G ++C +C G GT E CT
Sbjct: 611 EADCIDPGCSNHGVCIHGECHCSPGWGGSNCEILKTMCPDQCSGHGTYLQESGSCTCDPN 670
Query: 874 LTPGGCSRNAECIKTGTGTH------TCVCQQGWTG---NGRDCSEINNCLLPSAGGCHD 924
T CS E G+H TC C++GWTG N R C C +
Sbjct: 671 WTGPDCSN--EICSVDCGSHGVCMGGTCRCEEGWTGPACNQRACHP----------RCAE 718
Query: 925 NASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQE 984
+ +C +CEC +G+ NG C I C G C+ C +G W CVCQ
Sbjct: 719 HGTCK-----DGKCECSQGW--NGEHCT-IEGC---PGLCNSNGRCTLDQNG-WHCVCQP 766
Query: 985 GYEGDG 990
G+ G G
Sbjct: 767 GWRGAG 772
Score = 86.7 bits (213), Expect = 3e-16
Identities = 138/562 (24%), Positives = 205/562 (36%), Gaps = 121/562 (21%)
Query: 432 YFVKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIFNSDK--DNQIKLKLHGGKKKVKIIQG 489
YF+ +H+ ++ N T ++G++ NSD N + L K Q
Sbjct: 327 YFIAMHLFGLNWQLQQTEND------TFENGKV-NSDTMPTNTVSLPSGDNGKLGGFTQE 379
Query: 490 DIIASNGLLHILDRAMDKLEPTFESNNEQTIMTMLQPRYSKFRSLLEETNLGHALDEDGV 549
+ +G L I RA+ ++ P ++ I QP++ KF L++ L G+
Sbjct: 380 NNTIDSGELDIGRRAIQEIPPGIFWRSQLFID---QPQFLKFNISLQKDALIGVYGRKGL 436
Query: 550 GGPYTIFVPNNEALNNMKDGTLDYLLSPEGSRKLLELVRY-HIVPFTQLEVATLISTPHI 608
+T + + DG+ L R LLE R L A I ++
Sbjct: 437 PPSHTQY-----DFVELLDGSR---LIAREQRSLLETERAGRQARSVSLHEAGFIQ--YL 486
Query: 609 RSMANQLIQFNTTDNG-QILANDVAMEEIEITAKN---------GRIYTLTGVLIPPSIV 658
S L +N N Q+ N + +E + +N G + G L P
Sbjct: 487 DSGIWHLAFYNDGKNAEQVSFNTIVIESVVECPRNCHGNGECVSGTCHCFPGFLGPDCSR 546
Query: 659 PILPHRCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCARY 718
P C + K G C+ S W + T +C GR + CA
Sbjct: 547 AACPVLCSGNGQYSK-GRCLCFS--GWKGTECDVPTTQCIDPQC--GGRGICIMGSCA-- 599
Query: 719 CNATVKIPKCCKGFYGPDCNQC----PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQ 774
C G+ G C + PG CS +G C +G C C G+ GS
Sbjct: 600 ---------CNSGYKGESCEEADCIDPG-----CSNHGVCI-----HGECHCSPGWGGSN 640
Query: 775 CQF--------CS--------------DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTG 812
C+ CS DPN GP C+ + C+ S G C+ G
Sbjct: 641 CEILKTMCPDQCSGHGTYLQESGSCTCDPNWTGPDCSNEI------CSVDCGSHGVCMGG 694
Query: 813 TCR--DGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDP 870
TCR +G G C+++ AC P C H TC+ C C G+ G+ C+ ++
Sbjct: 695 TCRCEEGWTGPACNQR--ACHPR---CAEHGTCK----DGKCECSQGWNGEH--CT-IEG 742
Query: 871 CTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRD------CSEINNCLLPSAGGCHD 924
C GL C+ N C G H CVCQ GW G G D C++ + C D
Sbjct: 743 CPGL----CNSNGRCTLDQNGWH-CVCQPGWRGAGCDVAMETLCTDSKDNEGDGLIDCMD 797
Query: 925 NASCLYVGPGQNECECKKGFRG 946
CL Q+ C+ + RG
Sbjct: 798 PDCCL-----QSSCQNQPYCRG 814
Score = 75.9 bits (185), Expect = 5e-13
Identities = 80/290 (27%), Positives = 106/290 (36%), Gaps = 83/290 (28%)
Query: 100 CCPGRWGPDC--IECP---GGAGSPCNGRGSCAEGMEGN--------------------- 133
C PG GPDC CP G G GR C G +G
Sbjct: 535 CFPGFLGPDCSRAACPVLCSGNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICI 594
Query: 134 -GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKC 192
G+C+C G+ G E+C + + P CS+ HGVC G C C + G C
Sbjct: 595 MGSCACNSGYKG---ESCEEADCIDPGCSN-----HGVCI-----HGECHCSPGWGGSNC 641
Query: 193 DKPIPECAALLCPENSRCS-PSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAH 251
E +CP+ +CS T + C C PN+ G D N C H
Sbjct: 642 -----EILKTMCPD--QCSGHGTYLQESGSCTCDPNWTGP----DCSNEICSVDCGSHGV 690
Query: 252 CTYLGPNRHSCTCQEGYRG---DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECK 308
C +C C+EG+ G + + C P C T CK DG CEC
Sbjct: 691 CM-----GGTCRCEEGWTGPACNQRACHP---------RCAEHGT-CK-DG----KCECS 730
Query: 309 EHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDG 358
+ + G C++ C+ N CT G C+CQ G+ G G
Sbjct: 731 QGWN----GEHCTIEG---CPGLCNSNGRCTLDQNG-WHCVCQPGWRGAG 772
Score = 73.6 bits (179), Expect = 2e-12
Identities = 75/290 (25%), Positives = 97/290 (33%), Gaps = 79/290 (27%)
Query: 1333 TRECCAGFFGPQCQ--PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET----- 1385
T C GF GP C CP +C GNG G C C G+ GT C+
Sbjct: 532 TCHCFPGFLGPDCSRAACPV----LCSGNG-----QYSKGRCLCFSGWKGTECDVPTTQC 582
Query: 1386 -----------------CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCD 1428
C G G C++A G N G G C C GW G +C+
Sbjct: 583 IDPQCGGRGICIMGSCACNSGYKGESCEEADCIDPGCSNHGVCIHGECHCSPGWGGSNCE 642
Query: 1429 NATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADC 1488
T C C L S SC C + G + EI + C + C
Sbjct: 643 ILKT--MCPDQCSGHGTYLQES---GSCTCDPNWTGPDC------SNEICSVDCGSHGVC 691
Query: 1489 KRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGC-DKNAECTQTGPNQAACNCLPAYT 1547
T C C+ G+TG +P HG C D EC+Q
Sbjct: 692 MGGT-----CRCEEGWTGPACNQRACHPRCAEHGTCKDGKCECSQ--------------G 732
Query: 1548 GDGKVCTLINVCLTKNGGCSEFAICNHTGQVERT-----CTCKPNYIGDG 1592
+G+ CT+ GC +CN G+ C C+P + G G
Sbjct: 733 WNGEHCTI--------EGCP--GLCNSNGRCTLDQNGWHCVCQPGWRGAG 772
Score = 68.6 bits (166), Expect = 8e-11
Identities = 63/247 (25%), Positives = 90/247 (36%), Gaps = 58/247 (23%)
Query: 110 IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHG 169
+ECP C+G G C +GTC C GF G C A C +C+
Sbjct: 516 VECPRN----CHGNGECV-----SGTCHCFPGFLGPDCSRAA--------CPVLCS---- 554
Query: 170 VCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYR 229
+G G C C+S + G +CD P +C C C + C C Y+
Sbjct: 555 --GNGQYSKGRCLCFSGWKGTECDVPTTQCIDPQCGGRGICIMGS-------CACNSGYK 605
Query: 230 GDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCP 289
G+ C+ + C+ C H C + C C G+ G C+I CP
Sbjct: 606 GES--CEEAD-CIDPGCSNHGVCIH-----GECHCSPGWGGSN--------CEILKTMCP 649
Query: 290 TKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECI 349
+ + C C ++ G CS +IC D H V G T C
Sbjct: 650 DQCSGHGTYLQESGSCTCDPNW----TGPDCS-NEICSVDCGSH------GVCMGGT-CR 697
Query: 350 CQKGYVG 356
C++G+ G
Sbjct: 698 CEEGWTG 704
Score = 68.6 bits (166), Expect = 8e-11
Identities = 65/244 (26%), Positives = 83/244 (34%), Gaps = 56/244 (22%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS 159
C P GPDC C G C GTC C+EG+ G AC + P
Sbjct: 667 CDPNWTGPDCSN--EICSVDCGSHGVCM-----GGTCRCEEGWTGPAC----NQRACHPR 715
Query: 160 CSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENK 219
C+ HG C DG CEC + G C I C LC N RC T D+N
Sbjct: 716 CAE-----HGTCK-----DGKCECSQGWNGEHC--TIEGCPG-LCNSNGRC---TLDQNG 759
Query: 220 LECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQV-CLPV 278
C C P +RG G CD L CT + GDG + C+
Sbjct: 760 WHCVCQPGWRGAG--CDVAMETL-------------------CTDSKDNEGDGLIDCMDP 798
Query: 279 DPC-------QINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNP 331
D C Q P + S K Y +G T + ++P
Sbjct: 799 DCCLQSSCQNQPYCRGLPDPQDIISQSLQSPSQQAAKSFYDRISFLIGSDSTHVIPGESP 858
Query: 332 CHRN 335
+++
Sbjct: 859 FNKS 862
Score = 56.6 bits (135), Expect = 3e-07
Identities = 53/186 (28%), Positives = 75/186 (40%), Gaps = 48/186 (25%)
Query: 2011 PCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECN 2070
P C +G+C SG C C G+ GP C A C CS + + C C
Sbjct: 519 PRNCHGNGECV-----SGTCHCFPGFLGPDCSR-----AACPVLCSGNGQYSKGR-CLCF 567
Query: 2071 LDYEG---DGITCTVVDFCKQDNGGCAKVARCSQKGTKV--SCSCQKGYKGDGHSCTEID 2125
++G D T +D +C +G + SC+C GYKG+ SC E
Sbjct: 568 SGWKGTECDVPTTQCID------------PQCGGRGICIMGSCACNSGYKGE--SCEE-- 611
Query: 2126 PCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCE-PEQLPIDRC------LQDN 2178
AD ++ GC H C +C C + G NCE + + D+C LQ++
Sbjct: 612 --ADCIDPGCSNHGVCI-----HGECHCSPGW--GGSNCEILKTMCPDQCSGHGTYLQES 662
Query: 2179 GQCHAD 2184
G C D
Sbjct: 663 GSCTCD 668
Score = 56.2 bits (134), Expect = 4e-07
Identities = 54/216 (25%), Positives = 81/216 (37%), Gaps = 49/216 (22%)
Query: 1876 GIDCLLIDPTLGGRCDTFTTFDASGECGSCVNTPSCPRWSKPKGVKQKCLYNLPFKRNLE 1935
G +C ++ +C T+ E GSC P+ W+ P + C +
Sbjct: 638 GSNCEILKTMCPDQCSGHGTY--LQESGSCTCDPN---WTGPDCSNEICSVD-------- 684
Query: 1936 GCRERCSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGT 1995
C + RC +G+ G C P C G C D G+C+C+ G+NG
Sbjct: 685 -CGSHGVCMGGTCRCEEGWTGPACNQRACHPR--CAEHGTCKD-----GKCECSQGWNGE 736
Query: 1996 ACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPC 2055
C + + P C+ +G+C G C+C+ GW G CD + +CT
Sbjct: 737 HCTI--------EGCPGLCNSNGRCTLDQNG-WHCVCQPGWRGAGCD--VAMETLCTD-- 783
Query: 2056 SAHATCKENNTCECNLDYEGDG-ITCTVVDFCKQDN 2090
+ D EGDG I C D C Q +
Sbjct: 784 --------------SKDNEGDGLIDCMDPDCCLQSS 805
Score = 50.8 bits (120), Expect = 2e-05
Identities = 50/202 (24%), Positives = 75/202 (37%), Gaps = 48/202 (23%)
Query: 1393 IHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG 1452
+ C + C HG G G+C C G+ G C A C+G S
Sbjct: 516 VECPRNC---HGN---GECVSGTCHCFPGFLGPDCSRAACPVLCSGNGQYS--------- 560
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
C C +G++ GT C + + + C + C + C C +GY G+ C
Sbjct: 561 KGRCLCFSGWK--GTECD-VPTTQCIDPQCGGRGICIMGS-----CACNSGYKGES--CE 610
Query: 1513 E---INPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLI-NVCLTKNGGCSE 1568
E I+P NHG C C+C P + G C ++ +C + G
Sbjct: 611 EADCIDPGCSNHGVC-----------IHGECHCSPGWGGSN--CEILKTMCPDQCSGHGT 657
Query: 1569 FAICNHTGQVERTCTCKPNYIG 1590
+ Q +CTC PN+ G
Sbjct: 658 YL------QESGSCTCDPNWTG 673
Score = 47.4 bits (111), Expect = 2e-04
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 16/98 (16%)
Query: 1333 TRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYG 1392
T C G+ GP C + + C +G C DG CEC +G++G C EG
Sbjct: 695 TCRCEEGWTGPACNQRACHPR--CAEHGTCKDGK-----CECSQGWNGEHCTI--EG--- 742
Query: 1393 IHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNA 1430
C C+ +GRC G C C GWRG CD A
Sbjct: 743 --CPGLCNS-NGRCTLDQNG-WHCVCQPGWRGAGCDVA 776
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 99.4 bits (246), Expect = 4e-20
Identities = 85/293 (29%), Positives = 113/293 (38%), Gaps = 48/293 (16%)
Query: 1909 PSCPRWSKPKGVKQKCLYNLPFKRNLEGCRERCSLVIQIPRCCKGYFGRDCQACPGGPDA 1968
P R + P+ ++ K L P K+ C+ +L +Q C C +
Sbjct: 888 PGIARCAGPQDMEGKLLLTTPAKKF--ECQGPPTLAVQAK----------CDLCLS---S 932
Query: 1969 PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQC--DDGITG 2026
PC N+G C + C C +G+ G CE+ C C + G C +G
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSL-----DSCSSGPCENGGTCHAQEGEDA 987
Query: 2027 SGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHA-----TCKE---NNTCECNLDYEGDGI 2078
C C TG+ GP+C V T C HA C + N TC+C L YEG
Sbjct: 988 PFTCSCPTGFEGPTC-------GVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKAC 1040
Query: 2079 TCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTE-IDPCADGLNGGCHE 2137
+VD C D C A+C C C GY GD +C+E D C D C
Sbjct: 1041 E-QLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGD--NCSENQDDCRD---HRCQN 1094
Query: 2138 HATCKMTGPGKHKCECKSHYVGDGLNCE-PEQLPIDRCLQDNGQCHADAKCVD 2189
A C M + C C Y G CE P LP + + +C A CVD
Sbjct: 1095 GAQC-MDEVNSYSCLCAEGY--SGQLCEIPPHLPAPKSPCEGTECQNGANCVD 1144
Score = 86.3 bits (212), Expect = 4e-16
Identities = 75/238 (31%), Positives = 102/238 (42%), Gaps = 36/238 (15%)
Query: 91 CRKDYLQP-RC-CP-GRWGPDC-IECPGGAGSPCNGRGSC--AEGMEGNGTCSCQEGFGG 144
C D L+ RC CP G G DC + + PC G+C EG + TCSC GF G
Sbjct: 940 CHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEG 999
Query: 145 TACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALL- 203
C DD +C++ CV GV G+ TC+C Y G C++ + C+ L
Sbjct: 1000 PTCGVNTDD-CVDHACANGGVCVDGV------GNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 204 -CPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSC 262
C ++C + + C+C+P Y GD + + C C A C N +SC
Sbjct: 1053 PCQHEAQCVGTPDGP---RCECMPGYAGD-NCSENQDDCRDHRCQNGAQCMD-EVNSYSC 1107
Query: 263 TCQEGYRGDGQVC-------LPVDPCQ----INFGNCPTKST--VCK-YDGPGQSHCE 306
C EGY GQ+C P PC+ N NC + VC+ G G CE
Sbjct: 1108 LCAEGY--SGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECE 1163
Score = 78.6 bits (192), Expect = 7e-14
Identities = 67/246 (27%), Positives = 97/246 (39%), Gaps = 47/246 (19%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNG--TCICEEGFQGSQCQFCSDP 781
C G+ G DC + C G PC G C G + TC C GF+G C +D
Sbjct: 952 CPSGYKGRDCEVSLDSCSSG---PCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDD 1008
Query: 782 NKYGPRCNKKCLCVHGTCNNRIDSDGACLTGT------CRDGSAGRLCDKQTSACGPYVQ 835
CV C N G C+ G C G+ C++ C P +
Sbjct: 1009 ------------CVDHACAN----GGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLN 1052
Query: 836 FCHIHATCEYSNGTASCICKAGYEGDGTLCSE-MDPCTGLTPGGCSRNAECIKTGTGTHT 894
C A C + C C GY GD CSE D C C A+C+ +++
Sbjct: 1053 PCQHEAQCVGTPDGPRCECMPGYAGDN--CSENQDDC---RDHRCQNGAQCMDE-VNSYS 1106
Query: 895 CVCQQGWTGNGRDCSEINNCLLPSA----GGCHDNASCLYVGPGQNECECKKGFRGNGID 950
C+C +G+ +G+ C + P + C + A+C+ G + C+C GF G +
Sbjct: 1107 CLCAEGY--SGQLCEIPPHLPAPKSPCEGTECQNGANCVDQG-NRPVCQCLPGF--GGPE 1161
Query: 951 CEPITS 956
CE + S
Sbjct: 1162 CEKLLS 1167
Score = 72.8 bits (177), Expect = 4e-12
Identities = 59/240 (24%), Positives = 84/240 (35%), Gaps = 19/240 (7%)
Query: 1356 CFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGS 1415
C G C + C C G+ G CE + C+ +C +G +
Sbjct: 934 CQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTC---HAQEGEDAPFT 990
Query: 1416 CDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTIC-TAINA 1474
C C G+ G C T+D + C C+ DG + C Q G C ++
Sbjct: 991 CSCPTGFEGPTC-GVNTDDCVDHACANGGVCV---DGVGNYTCQCPLQYEGKACEQLVDL 1046
Query: 1475 CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTG 1534
C C +A C T G R C C GY GD C E +H C A+C
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPR-CECMPGYAGDN--CSENQDDCRDH-RCQNGAQCMDE- 1101
Query: 1535 PNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVER----TCTCKPNYIG 1590
N +C C Y+ G++C + C N V++ C C P + G
Sbjct: 1102 VNSYSCLCAEGYS--GQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGG 1159
Score = 71.6 bits (174), Expect = 9e-12
Identities = 69/262 (26%), Positives = 96/262 (36%), Gaps = 46/262 (17%)
Query: 743 GFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP---RCNKKC-LCVHGT 798
G+ P G +CA G + + +CQ GP KC LC+
Sbjct: 884 GYKEP--GIARCAGPQDMEGKLLLTTPAKKFECQ--------GPPTLAVQAKCDLCLSSP 933
Query: 799 CNNRIDSDGACLTG-------TCRDGSAGRLCDKQTSAC--GPYVQFCHIHATCEYSNGT 849
C N+ G C C G GR C+ +C GP C TC G
Sbjct: 934 CQNQ----GTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGP----CENGGTCHAQEGE 985
Query: 850 AS---CICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGR 906
+ C C G+EG T D C C+ C+ G G +TC C + G+
Sbjct: 986 DAPFTCSCPTGFEGP-TCGVNTDDCVD---HACANGGVCVD-GVGNYTCQCPLQY--EGK 1038
Query: 907 DCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHP 966
C ++ + P C A C+ G CEC G+ G+ E C + +C
Sbjct: 1039 ACEQLVDLCSPDLNPCQHEAQCVGTPDGPR-CECMPGYAGDNCS-ENQDDCRDH--RCQN 1094
Query: 967 LASCQSTSSGVWSCVCQEGYEG 988
A C + +SC+C EGY G
Sbjct: 1095 GAQCMDEVNS-YSCLCAEGYSG 1115
Score = 69.7 bits (169), Expect = 3e-11
Identities = 60/225 (26%), Positives = 86/225 (38%), Gaps = 29/225 (12%)
Query: 1336 CCAGFFGPQCQPCPGNAQN-VCFGNGIC--LDGVNGTGVCECGEGFSGTACETCTEGKYG 1392
C +G+ G C+ + + C G C +G + C C GF G C T+
Sbjct: 952 CPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVD 1011
Query: 1393 IHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCN---GTCHTSANCLTN 1449
C CV G +G+ +C C + + G C+ D C+ C A C+
Sbjct: 1012 HACANGGVCVDG------VGNYTCQCPLQYEGKACEQLV--DLCSPDLNPCQHEAQCVGT 1063
Query: 1450 SDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGI 1509
DG C+C G+ G+ C+ N + + C A C C C GY+G
Sbjct: 1064 PDG-PRCECMPGYAGDN--CSE-NQDDCRDHRCQNGAQCMDEV-NSYSCLCAEGYSGQ-- 1116
Query: 1510 VCLEINPCLE------NHGGCDKNAECTQTGPNQAACNCLPAYTG 1548
+C EI P L C A C G N+ C CLP + G
Sbjct: 1117 LC-EIPPHLPAPKSPCEGTECQNGANCVDQG-NRPVCQCLPGFGG 1159
Score = 65.9 bits (159), Expect = 5e-10
Identities = 52/211 (24%), Positives = 77/211 (36%), Gaps = 25/211 (11%)
Query: 1404 GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNC-NGTCHTSANC--LTNSDGTASCKCAA 1460
G C+ PL C C G++G C+ + D+C +G C C D +C C
Sbjct: 938 GTCHNDPLEVYRCACPSGYKGRDCE--VSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPT 995
Query: 1461 GFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLEN 1520
GF+G +N + + C+ C G C C Y G L ++ C +
Sbjct: 996 GFEGP---TCGVNTDDCVDHACANGGVCVDGV-GNYTCQCPLQYEGKACEQL-VDLCSPD 1050
Query: 1521 HGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVER 1580
C A+C T P+ C C+P Y GD C C + N ++
Sbjct: 1051 LNPCQHEAQCVGT-PDGPRCECMPGYAGDN--------CSENQDDCRDHRCQNGAQCMDE 1101
Query: 1581 ----TCTCKPNYIGDGFTCRGSIYQELPKNP 1607
+C C Y G C + PK+P
Sbjct: 1102 VNSYSCLCAEGYSGQ--LCEIPPHLPAPKSP 1130
Score = 58.2 bits (139), Expect = 1e-07
Identities = 37/134 (27%), Positives = 54/134 (40%), Gaps = 12/134 (8%)
Query: 1343 PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCV 1402
P C+PC + + +GIC +C C G+ G C+ +G H CV
Sbjct: 1337 PGCEPC----RKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGH-----KCV 1387
Query: 1403 HGRCNQGPLGDGSCDCDVGWRGVHCDNA-TTEDNCNGTCHTSANCLTNSDGTASCKCAAG 1461
HG+C SC C G+ G C+ A + C G +C + A C C G
Sbjct: 1388 HGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPG 1447
Query: 1462 FQGNGTICTAINAC 1475
F +G +C + C
Sbjct: 1448 F--SGELCEQESEC 1459
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 14/125 (11%)
Query: 751 NGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACL 810
+G C + C CE G+ G C +D +G + CVHG C + D
Sbjct: 1349 HGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHK------CVHGQC---VPLDALSY 1399
Query: 811 TGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGT--ASCICKAGYEGDGTLCSEM 868
+ C+DG +G LC++ + P +H C+ ++GT A C+C G+ G+ LC +
Sbjct: 1400 SCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQ-ASGTKGAHCVCDPGFSGE--LCEQE 1456
Query: 869 DPCTG 873
C G
Sbjct: 1457 SECRG 1461
Score = 56.6 bits (135), Expect = 3e-07
Identities = 46/178 (25%), Positives = 64/178 (35%), Gaps = 14/178 (7%)
Query: 181 CECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCD-PIN 239
C C S Y G C+ + C++ C C ++ C C + +G C +
Sbjct: 950 CACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGF--EGPTCGVNTD 1007
Query: 240 PCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKS-TVCKYD 298
C+ C C G ++C C Y G L VD C + C ++ V D
Sbjct: 1008 DCVDHACANGGVCVD-GVGNYTCQCPLQYEGKACEQL-VDLCSPDLNPCQHEAQCVGTPD 1065
Query: 299 GPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
GP CEC Y G CS D+ C A C C+C +GY G
Sbjct: 1066 GP---RCECMPGY----AGDNCSENQDDCRDHRCQNGAQCMDEV-NSYSCLCAEGYSG 1115
Score = 55.1 bits (131), Expect = 9e-07
Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 6/118 (5%)
Query: 1401 CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAA 1460
C+HG C C C+ GW G+HCD + C+G C+ + SC+C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQ-PADGPCHGHKCVHGQCVPLDALSYSCQCQD 1405
Query: 1461 GFQGNGTICTAINA-CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPC 1517
G+ +G +C A E G C+ + C C G++G+ +C + + C
Sbjct: 1406 GY--SGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE--LCEQESEC 1459
Score = 52.0 bits (123), Expect = 7e-06
Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 28/161 (17%)
Query: 166 CVHGVCNSGLDGDGTCECYSAYTGPKCDKPIP-ECAALLCPENSRCSPSTEDENKLECKC 224
C+HG+C C C + + G CD+P C C + +C P D C+C
Sbjct: 1347 CLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKC-VHGQCVPL--DALSYSCQC 1403
Query: 225 LPNYRGDGKYCDP----INPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDP 280
Y G C+ PC C H HC G C C G+ G++C
Sbjct: 1404 QDGY--SGALCNQAGALAEPCRGLQC-LHGHCQASGTKGAHCVCDPGF--SGELCEQESE 1458
Query: 281 C-----------QINFGNCPTKSTV----CKYDGPGQSHCE 306
C Q + C T + C+ PGQ C+
Sbjct: 1459 CRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQ 1499
Score = 50.4 bits (119), Expect = 2e-05
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 21/168 (12%)
Query: 2007 PDCLPCG---CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKE 2063
P C PC C HG C T C CE GW G CD A P C H C
Sbjct: 1337 PGCEPCRKLYCL-HGICQPNATPGPMCHCEAGWVGLHCDQPADGP--CHGHKCVHGQCVP 1393
Query: 2064 ----NNTCECNLDYEGDGITCTVVDFCKQDNGGCAKV-ARCSQKGTK-VSCSCQKGYKGD 2117
+ +C+C Y G C + G + C GTK C C G+ G+
Sbjct: 1394 LDALSYSCQCQDGY--SGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE 1451
Query: 2118 GHSCTEIDPCADGLNGGCHE----HATCKMTGPGKHKCECKSHYVGDG 2161
C + C H+ +A C+ T P EC+ G G
Sbjct: 1452 --LCEQESECRGDPVRDFHQVQRGYAICQTTRP-LSWVECRGSCPGQG 1496
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 10/100 (10%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNR----GVCLDQYSATGECKCNTGFNGTACEMCWPGRF 2005
C G+ G C D PC+ G C+ + + C+C G++G C G
Sbjct: 1364 CEAGWVGLHCDQ---PADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSGALCNQA--GAL 1418
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQA 2045
C C HG C T C+C+ G++G C+ ++
Sbjct: 1419 AEPCRGLQCL-HGHCQASGTKGAHCVCDPGFSGELCEQES 1457
Score = 44.7 bits (104), Expect = 0.001
Identities = 33/130 (25%), Positives = 48/130 (36%), Gaps = 17/130 (13%)
Query: 1969 PCNN----RGVCLDQYSATGECKCNTGFNGTACEMCWPGR-FGPDCLPCGCSDHGQCDDG 2023
PC G+C + C C G+ G C+ G G C+ HGQC
Sbjct: 1341 PCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCV------HGQCVPL 1394
Query: 2024 ITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT----CECNLDYEGDGIT 2079
S C C+ G++G C+ L C H C+ + T C C+ + G+
Sbjct: 1395 DALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE--L 1452
Query: 2080 CTVVDFCKQD 2089
C C+ D
Sbjct: 1453 CEQESECRGD 1462
Score = 42.7 bits (99), Expect = 0.005
Identities = 54/203 (26%), Positives = 75/203 (36%), Gaps = 30/203 (14%)
Query: 1856 NGQTCRIVQRE-LLFDLGVAYGIDCLLIDPTLGGRCDTFTTFDASGECGSCVN-----TP 1909
NG TC + E F G + PT G D A G CV+ T
Sbjct: 975 NGGTCHAQEGEDAPFTCSCPTGFE----GPTCGVNTDDCVDH-ACANGGVCVDGVGNYTC 1029
Query: 1910 SCPRWSKPKGVKQKCLYNLPFKRNLEGCRE--RCSLVIQIPRC--CKGYFGRDCQACPGG 1965
CP + K +Q P +L C+ +C PRC GY G +C
Sbjct: 1030 QCPLQYEGKACEQLVDLCSP---DLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDD 1086
Query: 1966 -PDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGI 2024
D C N C+D+ ++ C C G++G CE+ P PC + +C +G
Sbjct: 1087 CRDHRCQNGAQCMDEVNSYS-CLCAEGYSGQLCEI--PPHLPAPKSPC---EGTECQNGA 1140
Query: 2025 TGSGQ-----CLCETGWTGPSCD 2042
Q C C G+ GP C+
Sbjct: 1141 NCVDQGNRPVCQCLPGFGGPECE 1163
Score = 42.7 bits (99), Expect = 0.005
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 29/130 (22%)
Query: 81 SLSLPGCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCN-GRGSCAEGMEGNG----- 134
S L C+H + +C GP C PG AG C+ + C + NG
Sbjct: 1048 SPDLNPCQH-------EAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMD 1100
Query: 135 -----TCSCQEGFGGTACET-----CADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECY 184
+C C EG+ G CE G C + NCV C+C
Sbjct: 1101 EVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQ------GNRPVCQCL 1154
Query: 185 SAYTGPKCDK 194
+ GP+C+K
Sbjct: 1155 PGFGGPECEK 1164
Score = 41.6 bits (96), Expect = 0.010
Identities = 30/121 (24%), Positives = 45/121 (37%), Gaps = 14/121 (11%)
Query: 124 GSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCEC 183
G C C C+ G+ G C+ AD G CVHG C +C+C
Sbjct: 1350 GICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGH------KCVHGQCVPLDALSYSCQC 1403
Query: 184 YSAYTGPKCDKP---IPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINP 240
Y+G C++ C L C + T+ + C C P + G+ C+ +
Sbjct: 1404 QDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAH---CVCDPGF--SGELCEQESE 1458
Query: 241 C 241
C
Sbjct: 1459 C 1459
Score = 41.2 bits (95), Expect = 0.013
Identities = 45/173 (26%), Positives = 67/173 (38%), Gaps = 18/173 (10%)
Query: 830 CGPYVQFCHIHATCEYSNGTAS--CICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIK 887
C P + +H C+ N T C C+AG+ G C + P G G + +C+
Sbjct: 1339 CEPCRKLYCLHGICQ-PNATPGPMCHCEAGWVG--LHCDQ--PADGPCHGHKCVHGQCVP 1393
Query: 888 TGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGN 947
+++C CQ G+ +G C++ P G + C G C C GF G
Sbjct: 1394 LDALSYSCQCQDGY--SGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE 1451
Query: 948 GIDCEPITSCL-EQTGKCHPL----ASCQSTSSGVWSCVCQEGYEGDGFLCYG 995
CE + C + H + A CQ+T W C+ G G C G
Sbjct: 1452 --LCEQESECRGDPVRDFHQVQRGYAICQTTRPLSW-VECRGSCPGQG-CCQG 1500
Score = 39.7 bits (91), Expect = 0.038
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 25/124 (20%)
Query: 1323 CQPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGN------------GICLDGVNGTG 1370
C P +C GP+C+ PG A + C N C+D VN
Sbjct: 1047 CSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYS 1106
Query: 1371 VCECGEGFSGTACE------TCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRG 1424
C C EG+SG CE G C +CV +QG C C G+ G
Sbjct: 1107 -CLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCV----DQG--NRPVCQCLPGFGG 1159
Query: 1425 VHCD 1428
C+
Sbjct: 1160 PECE 1163
Score = 39.7 bits (91), Expect = 0.038
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 5/54 (9%)
Query: 727 KCCKGFYGPDCNQCPGGFSNPCSG----NGQCADSLGGNGTCICEEGFQGSQCQ 776
+C G+ G CNQ G + PC G +G C S C+C+ GF G C+
Sbjct: 1402 QCQDGYSGALCNQA-GALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCE 1454
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 97.4 bits (241), Expect = 2e-19
Identities = 56/164 (34%), Positives = 75/164 (45%), Gaps = 12/164 (7%)
Query: 1440 CHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCT 1499
C T+A C + +C+CA+G+QG+G C N C C + C PG C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVC-INLPGSYRCE 828
Query: 1500 CKAGY--TGDGIVCLEI----NPCLENHGGCDK--NAECTQTGPNQAACNCLPAYTGDGK 1551
C++GY D C+ I NPC + C A C G + +C CLP Y GDG
Sbjct: 829 CRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGH 888
Query: 1552 VCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTC 1595
CT ++ C C A C +T +C C+P Y GDGF C
Sbjct: 889 QCTDVDEC--SENRCHPAATCYNT-PGSFSCRCQPGYYGDGFQC 929
Score = 95.5 bits (236), Expect = 6e-19
Identities = 64/201 (31%), Positives = 91/201 (45%), Gaps = 37/201 (18%)
Query: 814 CRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPC-T 872
C DGS +CD CH +Y+ C C +GY+GDG C + + C T
Sbjct: 763 CYDGS--HMCDTTAR--------CHPGTGVDYT-----CECASGYQGDGRNCVDENECAT 807
Query: 873 GLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLL--PSAGGCHDN----- 925
G C N+ CI G++ C C+ G+ + + C+L P A C D
Sbjct: 808 GFHR--CGPNSVCINL-PGSYRCECRSGY----EFADDRHTCILITPPANPCEDGSHTCA 860
Query: 926 ----ASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCV 981
A C++ G C C G+ G+G C + C E +CHP A+C +T G +SC
Sbjct: 861 PAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSEN--RCHPAATCYNTP-GSFSCR 917
Query: 982 CQEGYEGDGFLCYGNAAVELS 1002
CQ GY GDGF C ++ L+
Sbjct: 918 CQPGYYGDGFQCIPDSTSSLT 938
Score = 89.7 bits (221), Expect = 3e-17
Identities = 56/168 (33%), Positives = 72/168 (42%), Gaps = 16/168 (9%)
Query: 203 LCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKI--CHPHAHCTYLGPNRH 260
+C +RC P T + C+C Y+GDG+ C N C C P++ C L P +
Sbjct: 769 MCDTTARCHPGTGVD--YTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINL-PGSY 825
Query: 261 SCTCQEGYR--GDGQVCL----PVDPCQINFGNC-PTKSTVCKYDGPGQSHCECKEHYQN 313
C C+ GY D C+ P +PC+ C P C + G C C Y
Sbjct: 826 RCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAG 885
Query: 314 FVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
G C+ D C S+N CH A C PG C CQ GY GDG C
Sbjct: 886 --DGHQCTDVDEC-SENRCHPAATCYNT-PGSFSCRCQPGYYGDGFQC 929
Score = 89.0 bits (219), Expect = 6e-17
Identities = 68/247 (27%), Positives = 90/247 (36%), Gaps = 27/247 (10%)
Query: 120 CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS---CSSVCNCVHGVCNSGLD 176
C+ C G + TC C G+ G C D+N C C++ L
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDG-RNCVDENECATGFHRCGPNSVCIN------LP 822
Query: 177 GDGTCECYSAYTGPKCDKPIPECAALLCPENS------RCSPSTEDE------NKLECKC 224
G CEC S Y + C + P N C+P+ + + C C
Sbjct: 823 GSYRCECRSGY---EFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCAC 879
Query: 225 LPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQIN 284
LP Y GDG C ++ C CHP A C Y P SC CQ GY GDG C+P +
Sbjct: 880 LPGYAGDGHQCTDVDECSENRCHPAATC-YNTPGSFSCRCQPGYYGDGFQCIPDSTSSLT 938
Query: 285 FGNCPTKSTVCKYDGPG-QSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAP 343
+ +Y PG + H + NF+P T C +P T P
Sbjct: 939 PCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPP 998
Query: 344 GRTECIC 350
G T C
Sbjct: 999 GSTPPHC 1005
Score = 85.1 bits (209), Expect = 8e-16
Identities = 61/189 (32%), Positives = 82/189 (43%), Gaps = 24/189 (12%)
Query: 2014 CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPP---CSAHATCKE---NNTC 2067
C +C G C C +G+ G V C C ++ C + C
Sbjct: 770 CDTTARCHPGTGVDYTCECASGYQGDG--RNCVDENECATGFHRCGPNSVCINLPGSYRC 827
Query: 2068 ECNLDYE--GDGITCTVV----DFCKQDNGGCAKV--ARCSQKG-TKVSCSCQKGYKGDG 2118
EC YE D TC ++ + C+ + CA ARC G + SC+C GY GDG
Sbjct: 828 ECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDG 887
Query: 2119 HSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQL-PIDRCLQD 2177
H CT++D C++ CH ATC T PG C C+ Y GDG C P+ + C Q
Sbjct: 888 HQCTDVDECSE---NRCHPAATCYNT-PGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQ 943
Query: 2178 NGQCHADAK 2186
Q HA A+
Sbjct: 944 --QRHAQAQ 950
Score = 80.1 bits (196), Expect = 3e-14
Identities = 63/235 (26%), Positives = 90/235 (38%), Gaps = 64/235 (27%)
Query: 738 NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHG 797
N C G S+ C +C G + TC C G+QG + C D N+
Sbjct: 761 NPCYDG-SHMCDTTARCHPGTGVDYTCECASGYQGDG-RNCVDENE-------------- 804
Query: 798 TCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAG 857
C TG R CGP ++ C G+ C C++G
Sbjct: 805 -----------CATGFHR--------------CGP-------NSVCINLPGSYRCECRSG 832
Query: 858 YE--GDGTLCSEMDPCTGLTPGGC-----SRNAECIKTGTGTHTCVCQQGWTGNGRDCSE 910
YE D C + P G + A C+ G T +C C G+ G+G C++
Sbjct: 833 YEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTD 892
Query: 911 INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP-----ITSCLEQ 960
++ C S CH A+C Y PG C C+ G+ G+G C P +T C +Q
Sbjct: 893 VDEC---SENRCHPAATC-YNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQ 943
Score = 73.2 bits (178), Expect = 3e-12
Identities = 55/195 (28%), Positives = 73/195 (37%), Gaps = 35/195 (17%)
Query: 1347 PCPGN----AQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCV 1402
P PGN ++C C G CEC G+ G C + + C+
Sbjct: 757 PTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDG-RNCVD-------ENECATG 808
Query: 1403 HGRCNQGPL-----GDGSCDCDVGWRGVH----CDNATTEDN-CNGTCHT-----SANCL 1447
RC + G C+C G+ C T N C HT A C+
Sbjct: 809 FHRCGPNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCV 868
Query: 1448 TNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD 1507
+ T SC C G+ G+G CT ++ C S C A C T PG C C+ GY GD
Sbjct: 869 HHGGSTFSCACLPGYAGDGHQCTDVDEC--SENRCHPAATCYNT-PGSFSCRCQPGYYGD 925
Query: 1508 GIVCL-----EINPC 1517
G C+ + PC
Sbjct: 926 GFQCIPDSTSSLTPC 940
Score = 57.0 bits (136), Expect = 2e-07
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Query: 2086 CKQDNGGCAKVARCSQ-KGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMT 2144
C + C ARC G +C C GY+GDG +C + + CA G + C ++ C +
Sbjct: 763 CYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFH-RCGPNSVC-IN 820
Query: 2145 GPGKHKCECKSHY--VGDGLNCEPEQLPIDRCLQDNGQC--HADAKCV 2188
PG ++CEC+S Y D C P + C + C A+CV
Sbjct: 821 LPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCV 868
Score = 46.6 bits (109), Expect = 3e-04
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 4/94 (4%)
Query: 1515 NPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC-N 1573
NPC + CD A C C C Y GDG+ C N C T C ++C N
Sbjct: 761 NPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCIN 820
Query: 1574 HTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNP 1607
G C + D TC I P NP
Sbjct: 821 LPGSYRCECRSGYEFADDRHTC---ILITPPANP 851
Score = 33.9 bits (76), Expect = 2.1
Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
Query: 2054 PCSAHATCKENNTCECNLDYEGDGITCTVVDF-------CKQDNGGCAKVARCSQKGTKV 2106
P S H T T E L+ + G V + C+ ++ C++ A C+ T
Sbjct: 450 PASGHTTPLSRGTYEVGLE-DNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGF 508
Query: 2107 SCSCQKGYKGDGHSC 2121
C CQ + G+G C
Sbjct: 509 CCHCQSKFYGNGKHC 523
Score = 33.1 bits (74), Expect = 3.6
Identities = 14/44 (31%), Positives = 20/44 (45%)
Query: 950 DCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLC 993
D P C + + C A C + ++C C GY+GDG C
Sbjct: 756 DPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNC 799
>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
Length = 2765
Score = 97.4 bits (241), Expect = 2e-19
Identities = 65/207 (31%), Positives = 83/207 (40%), Gaps = 50/207 (24%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM---------- 1999
C GY G C+ D C++ GVC++ GEC C+ G+ G CE+
Sbjct: 658 CSAGYKGEHCEEVDC-LDPTCSSHGVCVN-----GECLCSPGWGGLNCELARVQCPDQCS 711
Query: 2000 -------------CWPGRFGPDC----LPCGCSDHGQCDDGITGSGQCLCETGWTGPSCD 2042
C P GPDC C HG C G C CE GWTG +CD
Sbjct: 712 GHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDCGTHGVCI-----GGACRCEEGWTGAACD 766
Query: 2043 TQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQK 2102
+ VC P C H TCK+ CEC + G+ T +D C C RC+
Sbjct: 767 QR-----VCHPRCIEHGTCKDGK-CECREGWNGEHCT---IDGCPDL---CNGNGRCTLG 814
Query: 2103 GTKVSCSCQKGYKGDGHSCTEIDPCAD 2129
C CQ G++G G + CAD
Sbjct: 815 QNSWQCVCQTGWRGPGCNVAMETSCAD 841
Score = 89.7 bits (221), Expect = 3e-17
Identities = 69/237 (29%), Positives = 96/237 (40%), Gaps = 52/237 (21%)
Query: 1949 RCCKGYFGRDCQACPGGP-DAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGP 2007
+C G+ G +C D C G C+D G C C+ G+ G CE
Sbjct: 623 QCYSGWKGAECDVPMNQCIDPSCGGHGSCID-----GNCVCSAGYKGEHCEEV------- 670
Query: 2008 DCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHAT-CKENNT 2066
DCL CS HG C +G +CLC GW G +C+ V C CS H T +
Sbjct: 671 DCLDPTCSSHGVCVNG-----ECLCSPGWGGLNCELARV---QCPDQCSGHGTYLPDTGL 722
Query: 2067 CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKV--SCSCQKGYKGDGHSCTEI 2124
C C+ ++ G + V+ C D C G + +C C++G+ G
Sbjct: 723 CSCDPNWMGPDCS---VEVCSVD---------CGTHGVCIGGACRCEEGWTGAACDQRVC 770
Query: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQC 2181
P C EH TCK KCEC+ + G+ +C + P D C NG+C
Sbjct: 771 HP-------RCIEHGTCK-----DGKCECREGWNGE--HCTIDGCP-DLC-NGNGRC 811
Score = 87.0 bits (214), Expect = 2e-16
Identities = 85/328 (25%), Positives = 120/328 (36%), Gaps = 82/328 (25%)
Query: 688 CPANSEPTALFTHRCVYSGRFGS--LKSGCARYCNATVKIPK----CCKGFYGPDC---- 737
C N E + H + G G+ K+ C C+ + K C G+ G +C
Sbjct: 580 CHGNGECVSGVCH--CFPGFLGADCAKAACPVLCSGNGQYSKGTCQCYSGWKGAECDVPM 637
Query: 738 NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQF--CSDPNKYGPRCNKKCLCV 795
NQC C G+G C D G C+C G++G C+ C DP C+ +CV
Sbjct: 638 NQC---IDPSCGGHGSCID-----GNCVCSAGYKGEHCEEVDCLDPT-----CSSHGVCV 684
Query: 796 HGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICK 855
+G C C G G C+ C C H T Y T C C
Sbjct: 685 NGEC-------------LCSPGWGGLNCELARVQCPDQ---CSGHGT--YLPDTGLCSCD 726
Query: 856 AGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEIN-NC 914
+ G CS ++ C+ C + CI C C++GWTG D + C
Sbjct: 727 PNWMGPD--CS-VEVCSV----DCGTHGVCIGGA-----CRCEEGWTGAACDQRVCHPRC 774
Query: 915 LLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTS 974
+ G C D +CEC++G+ G + G+C +
Sbjct: 775 I--EHGTCKDG-----------KCECREGWNGEHCTIDGCPDLCNGNGRC-------TLG 814
Query: 975 SGVWSCVCQEGYEGDGFLCYGNAAVELS 1002
W CVCQ G+ G G N A+E S
Sbjct: 815 QNSWQCVCQTGWRGPGC----NVAMETS 838
Score = 80.5 bits (197), Expect = 2e-14
Identities = 69/277 (24%), Positives = 105/277 (37%), Gaps = 63/277 (22%)
Query: 111 ECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGV 170
+CP C+G G C G+ C C GF G C A C +C+
Sbjct: 575 DCPRN----CHGNGECVSGV-----CHCFPGFLGADCAKAA--------CPVLCS----- 612
Query: 171 CNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG 230
+G GTC+CYS + G +CD P+ +C C + C C C Y+G
Sbjct: 613 -GNGQYSKGTCQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDG-------NCVCSAGYKG 664
Query: 231 DGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPT 290
+ +C+ ++ CL C H C C C G+ G C++ CP
Sbjct: 665 E--HCEEVD-CLDPTCSSHGVCV-----NGECLCSPGWGGLN--------CELARVQCPD 708
Query: 291 KSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECIC 350
+ + P C C ++ G CS+ ++C D C + C A C C
Sbjct: 709 QCSGHGTYLPDTGLCSCDPNWM----GPDCSV-EVCSVD--CGTHGVCIGGA-----CRC 756
Query: 351 QKGYVG---DGLTCYGNIMER--LRELNTEPRGKWQG 382
++G+ G D C+ +E ++ E R W G
Sbjct: 757 EEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNG 793
Score = 75.5 bits (184), Expect = 6e-13
Identities = 79/288 (27%), Positives = 115/288 (39%), Gaps = 79/288 (27%)
Query: 100 CCPGRWGPDCIE--CPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFG 157
C PG G DC + CP C+G G ++G TC C G+ G C+ + +
Sbjct: 593 CFPGFLGADCAKAACP----VLCSGNGQYSKG-----TCQCYSGWKGAECDVPMNQCI-D 642
Query: 158 PSCSSVCNCVHG--VCNSGLDGD--------------------GTCECYSAYTGPKCDKP 195
PSC +C+ G VC++G G+ G C C + G C
Sbjct: 643 PSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNC--- 699
Query: 196 IPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHA--HCT 253
E A + CP+ + + L C C PN+ G C ++C H
Sbjct: 700 --ELARVQCPDQCSGHGTYLPDTGL-CSCDPNWMGPD--------CSVEVCSVDCGTHGV 748
Query: 254 YLGPNRHSCTCQEGYRG---DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEH 310
+G +C C+EG+ G D +VC P C I G C DG CEC+E
Sbjct: 749 CIGG---ACRCEEGWTGAACDQRVCHP--RC-IEHGTCK--------DGK----CECREG 790
Query: 311 YQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDG 358
+ G C++ D C + C+ N CT + +C+CQ G+ G G
Sbjct: 791 WN----GEHCTI-DGCP--DLCNGNGRCT-LGQNSWQCVCQTGWRGPG 830
Score = 70.5 bits (171), Expect = 2e-11
Identities = 66/248 (26%), Positives = 93/248 (37%), Gaps = 57/248 (22%)
Query: 1307 CIYTSYFMGRRTLFIGC-QPKCVR--TVITRECCA--GFFGPQCQPCPGNAQNVCFGNGI 1361
C+ ++ + G + C P C + EC G+ G C+ + C G+G
Sbjct: 656 CVCSAGYKGEHCEEVDCLDPTCSSHGVCVNGECLCSPGWGGLNCELARVQCPDQCSGHGT 715
Query: 1362 CLDGVNGTGVCECGEGFSGTAC--ETCTE--GKYGIHCDQACSC-------------VHG 1404
L TG+C C + G C E C+ G +G+ AC C H
Sbjct: 716 YLPD---TGLCSCDPNWMGPDCSVEVCSVDCGTHGVCIGGACRCEEGWTGAACDQRVCHP 772
Query: 1405 RC-NQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
RC G DG C+C GW G HC T D C C+ + C T + C C G++
Sbjct: 773 RCIEHGTCKDGKCECREGWNGEHC----TIDGCPDLCNGNGRC-TLGQNSWQCVCQTGWR 827
Query: 1464 GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIV-CLEINPCLENHG 1522
G G C A E S C GDG+V CL+ + CL++
Sbjct: 828 GPG--CNV--AMETS-------------------CADNKDNEGDGLVDCLDPDCCLQS-- 862
Query: 1523 GCDKNAEC 1530
C + C
Sbjct: 863 ACQNSLLC 870
Score = 69.7 bits (169), Expect = 3e-11
Identities = 82/297 (27%), Positives = 115/297 (38%), Gaps = 71/297 (23%)
Query: 1346 QPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE-------------------TC 1386
Q CP N C GNG C+ +GVC C GF G C C
Sbjct: 574 QDCPRN----CHGNGECV-----SGVCHCFPGFLGADCAKAACPVLCSGNGQYSKGTCQC 624
Query: 1387 TEGKYGIHCDQACS-CVHGRC-NQGPLGDGSCDCDVGWRGVHCDNATTED---NCNGTCH 1441
G G CD + C+ C G DG+C C G++G HC+ D + +G C
Sbjct: 625 YSGWKGAECDVPMNQCIDPSCGGHGSCIDGNCVCSAGYKGEHCEEVDCLDPTCSSHGVC- 683
Query: 1442 TSANCLTNSD-GTASC-----KCAAGFQGNGTIC--TAINACEISNGG--CSAK---ADC 1488
+ CL + G +C +C G+GT T + +C+ + G CS + DC
Sbjct: 684 VNGECLCSPGWGGLNCELARVQCPDQCSGHGTYLPDTGLCSCDPNWMGPDCSVEVCSVDC 743
Query: 1489 KRTTPGRRV---CTCKAGYTGDGIVCLEINPCLENHGGC-DKNAECTQ--TGPNQAACNC 1542
T G + C C+ G+TG +P HG C D EC + G + C
Sbjct: 744 --GTHGVCIGGACRCEEGWTGAACDQRVCHPRCIEHGTCKDGKCECREGWNGEHCTIDGC 801
Query: 1543 LPAYTGDGKVCTLIN-----VCLT--KNGGCSEFAICNHTGQVERTCTCKPNYIGDG 1592
G+G+ CTL VC T + GC+ +E +C + GDG
Sbjct: 802 PDLCNGNGR-CTLGQNSWQCVCQTGWRGPGCNV--------AMETSCADNKDNEGDG 849
Score = 46.2 bits (108), Expect = 4e-04
Identities = 48/198 (24%), Positives = 65/198 (32%), Gaps = 40/198 (20%)
Query: 1396 DQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTAS 1455
D C G G C C G+ G C A C+G S +
Sbjct: 571 DSVQDCPRNCHGNGECVSGVCHCFPGFLGADCAKAACPVLCSGNGQYS---------KGT 621
Query: 1456 CKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI- 1514
C+C +G++G + S GG + D C C AGY G+ C E+
Sbjct: 622 CQCYSGWKGAECDVPMNQCIDPSCGGHGSCIDGN--------CVCSAGYKGEH--CEEVD 671
Query: 1515 --NPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAIC 1572
+P +HG C N EC P NC A C+ L G
Sbjct: 672 CLDPTCSSHGVC-VNGECL-CSPGWGGLNCELARVQCPDQCSGHGTYLPDTG-------- 721
Query: 1573 NHTGQVERTCTCKPNYIG 1590
C+C PN++G
Sbjct: 722 --------LCSCDPNWMG 731
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 97.1 bits (240), Expect = 2e-19
Identities = 64/201 (31%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 1409 GPLGDGSCD-----CDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
GP+ +GS D C +G G C T+A C +C+C+ GF+
Sbjct: 658 GPVREGSPDALQNPCYIGTHG---------------CDTNAACRPGPRTQFTCECSIGFR 702
Query: 1464 GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT-GDGIVCLE------INP 1516
G+G C I+ C C + C PG C C GY D C+ IN
Sbjct: 703 GDGRTCYDIDECSEQPSVCGSHTICNNH-PGTFRCECVEGYQFSDEGTCVAVVDQRPINY 761
Query: 1517 CLENHGGCD--KNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNH 1574
C CD + A+C TG + C+CLP ++GDG+ C ++ C + C A C +
Sbjct: 762 CETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC--QPSRCHPDAFCYN 819
Query: 1575 TGQVERTCTCKPNYIGDGFTC 1595
T TC CKP Y GDGF C
Sbjct: 820 T-PGSFTCQCKPGYQGDGFRC 839
Score = 95.1 bits (235), Expect = 8e-19
Identities = 62/195 (31%), Positives = 85/195 (43%), Gaps = 26/195 (13%)
Query: 812 GTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTA-SCICKAGYEGDGTLCSEMDP 870
G R+GS D + C C +A C T +C C G+ GDG C ++D
Sbjct: 658 GPVREGSP----DALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDE 713
Query: 871 CTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGR-------DCSEINNCLLPSAGGCH 923
C+ P C + C GT C C +G+ + D IN C G H
Sbjct: 714 CSE-QPSVCGSHTIC-NNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYC----ETGLH 767
Query: 924 D-----NASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVW 978
+ A C+Y G C C GF G+G C+ + C Q +CHP A C +T G +
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDEC--QPSRCHPDAFCYNT-PGSF 824
Query: 979 SCVCQEGYEGDGFLC 993
+C C+ GY+GDGF C
Sbjct: 825 TCQCKPGYQGDGFRC 839
Score = 87.4 bits (215), Expect = 2e-16
Identities = 60/187 (32%), Positives = 82/187 (43%), Gaps = 26/187 (13%)
Query: 107 PDCIECPGGAGSP-CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCS---S 162
PD ++ P G+ C+ +C G TC C GF G TC D + CS S
Sbjct: 665 PDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDG-RTCYDID----ECSEQPS 719
Query: 163 VCNCVHGVCNSGLDGDGTCECYSAY--------TGPKCDKPIPECAALL----CPENSRC 210
VC H +CN+ G CEC Y +PI C L P+ ++C
Sbjct: 720 VCGS-HTICNNH-PGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQC 777
Query: 211 SPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRG 270
+ + C CLP + GDG+ C ++ C CHP A C Y P +C C+ GY+G
Sbjct: 778 IYT--GGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFC-YNTPGSFTCQCKPGYQG 834
Query: 271 DGQVCLP 277
DG C+P
Sbjct: 835 DGFRCVP 841
Score = 87.4 bits (215), Expect = 2e-16
Identities = 59/177 (33%), Positives = 80/177 (45%), Gaps = 31/177 (17%)
Query: 785 GPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCE 844
GPR C C G DG TC D C +Q S CG H C
Sbjct: 688 GPRTQFTCECSIG-----FRGDGR----TCYDIDE---CSEQPSVCGS-------HTICN 728
Query: 845 YSNGTASCICKAGYE--GDGTLCSEMDP-----C-TGLTPGGCSRNAECIKTGTGTHTCV 896
GT C C GY+ +GT + +D C TGL + A+CI TG ++TC
Sbjct: 729 NHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCS 788
Query: 897 CQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP 953
C G++G+G+ C +++ C CH +A C Y PG C+CK G++G+G C P
Sbjct: 789 CLPGFSGDGQACQDVDEC---QPSRCHPDAFC-YNTPGSFTCQCKPGYQGDGFRCVP 841
Score = 83.2 bits (204), Expect = 3e-15
Identities = 60/193 (31%), Positives = 81/193 (41%), Gaps = 33/193 (17%)
Query: 2007 PDCL--PC-----GCSDHGQCDDGITGSGQCLCETGWTGPS-----CDTQAVLPAVCTPP 2054
PD L PC GC + C G C C G+ G D + P+VC
Sbjct: 665 PDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVC--- 721
Query: 2055 CSAHATCKENN---TCECNLDYE-GDGITCTVV------DFCKQDNGGC--AKVARCSQK 2102
+H C + CEC Y+ D TC V ++C+ C + A+C
Sbjct: 722 -GSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYT 780
Query: 2103 G-TKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDG 2161
G + +CSC G+ GDG +C ++D C CH A C T PG C+CK Y GDG
Sbjct: 781 GGSSYTCSCLPGFSGDGQACQDVDECQPSR---CHPDAFCYNT-PGSFTCQCKPGYQGDG 836
Query: 2162 LNCEPEQLPIDRC 2174
C P ++ RC
Sbjct: 837 FRCVPGEVEKTRC 849
Score = 83.2 bits (204), Expect = 3e-15
Identities = 53/177 (29%), Positives = 72/177 (40%), Gaps = 17/177 (9%)
Query: 204 CPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRK--ICHPHAHCTYLGPNRHS 261
C N+ C P + C+C +RGDG+ C I+ C + +C H C P
Sbjct: 679 CDTNAACRPGPRTQ--FTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNN-HPGTFR 735
Query: 262 CTCQEGYR-GDGQVCL------PVDPCQINFGNCPTKSTV-CKYDGPGQSHCECKEHYQN 313
C C EGY+ D C+ P++ C+ NC C Y G C C +
Sbjct: 736 CECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSG 795
Query: 314 FVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCYGNIMERLR 370
G C D C+ CH +A C PG C C+ GY GDG C +E+ R
Sbjct: 796 --DGQACQDVDECQPSR-CHPDAFCYNT-PGSFTCQCKPGYQGDGFRCVPGEVEKTR 848
Score = 73.9 bits (180), Expect = 2e-12
Identities = 58/201 (28%), Positives = 74/201 (36%), Gaps = 28/201 (13%)
Query: 1332 ITRECCAGFFGPQCQPCPGNAQNVCF-------GNGICLDGVNGTGVCECGEGFSGTACE 1384
I R + GP + P QN C+ N C G CEC GF G
Sbjct: 648 ILRYALSNSIGPVREGSPDALQNPCYIGTHGCDTNAACRPGPRTQFTCECSIGFRGDG-R 706
Query: 1385 TCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNAT----TEDNCNGTC 1440
TC + C H CN P G C+C G++ D T + C
Sbjct: 707 TCYDIDECSEQPSVCGS-HTICNNHP-GTFRCECVEGYQ--FSDEGTCVAVVDQRPINYC 762
Query: 1441 HTS---------ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRT 1491
T A C+ + +C C GF G+G C ++ C+ S C A C T
Sbjct: 763 ETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSR--CHPDAFCYNT 820
Query: 1492 TPGRRVCTCKAGYTGDGIVCL 1512
PG C CK GY GDG C+
Sbjct: 821 -PGSFTCQCKPGYQGDGFRCV 840
Score = 47.8 bits (112), Expect = 1e-04
Identities = 50/193 (25%), Positives = 73/193 (37%), Gaps = 30/193 (15%)
Query: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHAD 2184
+PC G +G C +A C+ + CEC + GDG C ID C + C +
Sbjct: 670 NPCYIGTHG-CDTNAACRPGPRTQFTCECSIGFRGDGRTC----YDIDECSEQPSVCGSH 724
Query: 2185 AKCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAREACANEAATMATYNQ--LSYAQKAKYH 2242
C + G F G Y+ + +E +A +Q ++Y + H
Sbjct: 725 TIC------NNHPGTFRCECVEG-YQFS---------DEGTCVAVVDQRPINYCETG-LH 767
Query: 2243 LCS----AGWLETGRVAYPTAFASQNCGSGVVGIVDYGPRPNKSEMWDVFCYRMK-DVNC 2297
C A + TG +Y + G G +P++ D FCY C
Sbjct: 768 NCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHP-DAFCYNTPGSFTC 826
Query: 2298 TCKVGYVGDGFSC 2310
CK GY GDGF C
Sbjct: 827 QCKPGYQGDGFRC 839
Score = 42.0 bits (97), Expect = 0.008
Identities = 49/184 (26%), Positives = 64/184 (34%), Gaps = 31/184 (16%)
Query: 738 NQCPGGFSN-PCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGP-RCNKKCLCV 795
N C G N QC + G + TC C GF G Q C D ++ P RC+ C
Sbjct: 760 NYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG-QACQDVDECQPSRCHPDAFCY 818
Query: 796 HG------TCNNRIDSDG-ACLTGTCRD-----------GSAGRLCDKQTSACGPYVQFC 837
+ C DG C+ G G+AG ++ G +V C
Sbjct: 819 NTPGSFTCQCKPGYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPEC 878
Query: 838 HIH-----ATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGT 892
H C S G C+ + G E +GT G+TP S A I G
Sbjct: 879 DAHGHYAPTQCHGSTGYCWCVDRDGREVEGTRTR-----PGMTPPCLSTVAPPIHQGPAV 933
Query: 893 HTCV 896
T V
Sbjct: 934 PTAV 937
Score = 34.7 bits (78), Expect = 1.2
Identities = 16/30 (53%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 879 CSRNAECIKTGTGTHTCVCQQGWTGNGRDC 908
CS +AEC TG C C G+TGNGR C
Sbjct: 397 CSVHAECRDYATG-FCCSCVAGYTGNGRQC 425
Score = 33.1 bits (74), Expect = 3.6
Identities = 13/36 (36%), Positives = 16/36 (44%)
Query: 2086 CKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSC 2121
C + C+ A C T CSC GY G+G C
Sbjct: 390 CANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQC 425
Score = 32.7 bits (73), Expect = 4.7
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 1475 CEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
C + CS A+C+ G C+C AGYTG+G C+
Sbjct: 390 CANNRHQCSVHAECRDYATGF-CCSCVAGYTGNGRQCV 426
Score = 32.3 bits (72), Expect = 6.1
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 1/53 (1%)
Query: 1428 DNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTICTAINACEISNG 1480
D+ T N C A C + G C C AG+ GNG C A + + NG
Sbjct: 385 DSRQTCANNRHQCSVHAECRDYATGFC-CSCVAGYTGNGRQCVAEGSPQRVNG 436
Score = 32.0 bits (71), Expect = 8.0
Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 1517 CLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVC 1553
C N C +AEC C+C+ YTG+G+ C
Sbjct: 390 CANNRHQCSVHAECRDYATG-FCCSCVAGYTGNGRQC 425
>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
sapiens]
Length = 353
Score = 96.7 bits (239), Expect = 3e-19
Identities = 70/244 (28%), Positives = 94/244 (38%), Gaps = 38/244 (15%)
Query: 718 YCNATVKIPKCCK-GFYGPDCNQCPGGFSNPCSGNGQCA--DSLGGNGTCICEEGFQGSQ 774
+C T+K+ CC G YGPDC C GG PCSGNG C+ S G+G+C C G+QG
Sbjct: 119 FCVKTLKV--CCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPL 176
Query: 775 CQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDK----QTSAC 830
C C D R +C C+ + C + G + D+ C
Sbjct: 177 CTDCMDGYFSSLRNETHSICT--ACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDEC 234
Query: 831 GPYVQFCHIHATCEYSNGTASC-ICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTG 889
C C+ +NG+ +C C + G CTG PG C ECI
Sbjct: 235 AAEPPPCSAAQFCKNANGSYTCEECDSSCVG----------CTGEGPGNCK---ECI--- 278
Query: 890 TGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGI 949
G+ C++++ C L N +C Y PG C C GF
Sbjct: 279 ---------SGYAREHGQCADVDECSLAEKTCVRKNENC-YNTPGSYVCVCPDGFEETED 328
Query: 950 DCEP 953
C P
Sbjct: 329 ACVP 332
Score = 90.9 bits (224), Expect = 1e-17
Identities = 59/224 (26%), Positives = 89/224 (39%), Gaps = 37/224 (16%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCA--EGMEGNGTCSCQEGFGGTACETCADDNLFG 157
C PG +GPDC+ C GG+ PC+G G C+ +G+G+C C G+ G C C D
Sbjct: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYF-- 185
Query: 158 PSCSSVCNCVHGVCNSGLDGDGTC------ECYSAYTG-----------PKCDKPIPECA 200
SS+ N H +C + + TC +C G +C P C+
Sbjct: 186 ---SSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCS 242
Query: 201 ALLCPENSRCSPSTED----------ENKLECK-CLPNYRGDGKYCDPINPC--LRKICH 247
A +N+ S + E+ E CK C+ Y + C ++ C K C
Sbjct: 243 AAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCV 302
Query: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTK 291
Y P + C C +G+ C+P + G PT+
Sbjct: 303 RKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQ 346
Score = 88.2 bits (217), Expect = 9e-17
Identities = 63/220 (28%), Positives = 91/220 (41%), Gaps = 42/220 (19%)
Query: 1327 CVRTVITRECCA-GFFGPQCQPCPGNAQNVCFGNGICL-DGV-NGTGVCECGEGFSGTAC 1383
CV+T+ + CC+ G +GP C C G +Q C GNG C DG G G C C G+ G C
Sbjct: 120 CVKTL--KVCCSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLC 177
Query: 1384 ETCTEGKYG----------IHCDQACSCVHGRCNQGPLGDGSC-DCDVGW---------- 1422
C +G + CD++C G N+ C +C+VGW
Sbjct: 178 TDCMDGYFSSLRNETHSICTACDESCKTCSGLTNR------DCGECEVGWVLDEGACVDV 231
Query: 1423 -----RGVHCDNATTEDNCNG--TC-HTSANCL-TNSDGTASCK-CAAGFQGNGTICTAI 1472
C A N NG TC ++C+ +G +CK C +G+ C +
Sbjct: 232 DECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADV 291
Query: 1473 NACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
+ C ++ C K + TPG VC C G+ C+
Sbjct: 292 DECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACV 331
Score = 82.4 bits (202), Expect = 5e-15
Identities = 60/227 (26%), Positives = 81/227 (35%), Gaps = 32/227 (14%)
Query: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE--CKCNTGFNGTACEMCWPGRFG- 2006
C G +G DC AC GG PC+ G C S G+ C+C+ G+ G C C G F
Sbjct: 128 CSPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSS 187
Query: 2007 ----PDCLPCGCSDHGQCDDGITGSGQCLCETGWT---GPSCDTQAVLPAVCTPPCSAHA 2059
+ C + + G+T CE GW G D A PPCSA
Sbjct: 188 LRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDEC--AAEPPPCSAAQ 245
Query: 2060 TCKENNTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGH 2119
CK N TC D + C+ +G C GY +
Sbjct: 246 FCKNAN----------GSYTCEECD---------SSCVGCTGEGPGNCKECISGYAREHG 286
Query: 2120 SCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEP 2166
C ++D C+ ++ C T PG + C C + C P
Sbjct: 287 QCADVDECSLAEKTCVRKNENCYNT-PGSYVCVCPDGFEETEDACVP 332
Score = 39.7 bits (91), Expect = 0.038
Identities = 44/177 (24%), Positives = 66/177 (37%), Gaps = 21/177 (11%)
Query: 706 GRFGSLKSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCI 765
G F SL++ C A + K C G DC +C G+ G C D C
Sbjct: 183 GYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGW---VLDEGACVDV----DECA 235
Query: 766 CEEGFQGSQCQFCSDPN-KYG-PRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLC 823
E S QFC + N Y C+ C+ G + C++G R+ G+
Sbjct: 236 AEPP-PCSAAQFCKNANGSYTCEECDSSCV---GCTGEGPGNCKECISGYARE--HGQCA 289
Query: 824 DKQTSACGPYVQFC-HIHATCEYSNGTASCICKAGYEGDGTLC---SEMDPCTGLTP 876
D C + C + C + G+ C+C G+E C +E + G +P
Sbjct: 290 D--VDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESP 344
Score = 35.8 bits (81), Expect = 0.56
Identities = 59/270 (21%), Positives = 77/270 (28%), Gaps = 86/270 (31%)
Query: 768 EGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQT 827
E F + C P YGP CL G +G C DGS
Sbjct: 117 EWFCVKTLKVCCSPGTYGP----DCLACQGGSQRPCSGNGHC----SGDGSR-------- 160
Query: 828 SACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSE-----MDPCTGLTPGGCSRN 882
G SC C GY+G LC++ T C+
Sbjct: 161 -------------------QGDGSCRCHMGYQGP--LCTDCMDGYFSSLRNETHSICTAC 199
Query: 883 AECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHD------------------ 924
E KT +G RDC E + G C D
Sbjct: 200 DESCKTCSGL-----------TNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCK 248
Query: 925 -----------NASCL-YVGPGQNEC-ECKKGFRGNGIDCEPITSCLEQTGKC-HPLASC 970
++SC+ G G C EC G+ C + C C +C
Sbjct: 249 NANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENC 308
Query: 971 QSTSSGVWSCVCQEGYEGDGFLCYGNAAVE 1000
+T G + CVC +G+E C A E
Sbjct: 309 YNT-PGSYVCVCPDGFEETEDACVPPAEAE 337
Score = 33.9 bits (76), Expect = 2.1
Identities = 38/161 (23%), Positives = 51/161 (31%), Gaps = 46/161 (28%)
Query: 1941 CSLVIQIPRCCKGYFGRDCQACPGGPDAPCNNRGVCLDQYSATGE---CK----CNTGFN 1993
C+ + + C G RDC C G + G C+D E C C
Sbjct: 196 CTACDESCKTCSGLTNRDCGECEVG---WVLDEGACVDVDECAAEPPPCSAAQFCKNANG 252
Query: 1994 GTACEMCWPGRFG---------PDCLPCGCSDHGQCDD-------------------GIT 2025
CE C G +C+ +HGQC D
Sbjct: 253 SYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTP 312
Query: 2026 GSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT 2066
GS C+C G+ +T+ C PP A AT E+ T
Sbjct: 313 GSYVCVCPDGFE----ETE----DACVPPAEAEATEGESPT 345
>gi|126012562 low density lipoprotein-related protein 1 [Homo sapiens]
Length = 4544
Score = 95.5 bits (236), Expect = 6e-19
Identities = 70/252 (27%), Positives = 90/252 (35%), Gaps = 41/252 (16%)
Query: 1343 PQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE--TCTEGKYGIHCDQACS 1400
P P PG CF G C C C ++G CE C E HC
Sbjct: 4191 PPDAPRPGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWE-----HCRNG-- 4243
Query: 1401 CVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAA 1460
G C P G +C C G+ G C T+ C G C ++ C N C+C
Sbjct: 4244 ---GTCAASPSGMPTCRCPTGFTGPKC----TQQVCAGYCANNSTCTVNQGNQPQCRCLP 4296
Query: 1461 GFQGNGTICTAINACEI--SNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCL 1518
GF G + C+ +G C C+ G R C C A + G + + CL
Sbjct: 4297 GFLG--------DRCQYRQCSGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSRCL 4348
Query: 1519 ENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQV 1578
E G C N + CNC DG+V CLT G CS C ++
Sbjct: 4349 E--GACVVNKQ-----SGDVTCNCT-----DGRVAP---SCLTCVGHCSNGGSCTMNSKM 4393
Query: 1579 ERTCTCKPNYIG 1590
C C P+ G
Sbjct: 4394 MPECQCPPHMTG 4405
Score = 73.2 bits (178), Expect = 3e-12
Identities = 57/226 (25%), Positives = 75/226 (33%), Gaps = 38/226 (16%)
Query: 1324 QPKCVRTVITRECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTAC 1383
QPKC C + G +C+ C G C +G C C GF+G C
Sbjct: 4217 QPKC-------RCQPRYTGDKCEL--DQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKC 4267
Query: 1384 ETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTS 1443
T+ +C +C + NQ C C G+ G C C+G C
Sbjct: 4268 ---TQQVCAGYCANNSTCTVNQGNQP-----QCRCLPGFLGDRCQYR----QCSGYCENF 4315
Query: 1444 ANCLTNSDGTASCKCAAGFQGNGTICTAINACEISN-GGCSAKADCKRTTPGRRVCTCKA 1502
C +DG+ C+C A F+G + CE++ C A G C C
Sbjct: 4316 GTCQMAADGSRQCRCTAYFEG--------SRCEVNKCSRCLEGACVVNKQSGDVTCNCTD 4367
Query: 1503 GYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTG 1548
G CL G C CT C C P TG
Sbjct: 4368 GRVAPS--------CLTCVGHCSNGGSCTMNSKMMPECQCPPHMTG 4405
Score = 72.8 bits (177), Expect = 4e-12
Identities = 55/230 (23%), Positives = 82/230 (35%), Gaps = 67/230 (29%)
Query: 1963 PGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEM--CWPGRFGPDCLPCGCSDHGQC 2020
PG + C N G C +C+C + G CE+ CW C + G C
Sbjct: 4197 PGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCELDQCWEH----------CRNGGTC 4246
Query: 2021 DDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITC 2080
+G C C TG+TGP C Q VC C+ ++TC N
Sbjct: 4247 AASPSGMPTCRCPTGFTGPKCTQQ-----VCAGYCANNSTCTVN---------------- 4285
Query: 2081 TVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHAT 2140
+G + C C G+ GD + +G C T
Sbjct: 4286 ---------------------QGNQPQCRCLPGFLGDRCQYRQ-------CSGYCENFGT 4317
Query: 2141 CKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
C+M G +C C +++ +G CE + RCL+ G C + + D+
Sbjct: 4318 CQMAADGSRQCRCTAYF--EGSRCEVNK--CSRCLE--GACVVNKQSGDV 4361
Score = 65.1 bits (157), Expect = 9e-10
Identities = 58/244 (23%), Positives = 77/244 (31%), Gaps = 35/244 (14%)
Query: 113 PGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCN 172
PG C GSC C CQ + G CE C C G C
Sbjct: 4197 PGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCEL--------DQCWEHCRN-GGTCA 4247
Query: 173 SGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDG 232
+ G TC C + +TGPKC + + CA C NS C + N+ +C+CLP + GD
Sbjct: 4248 ASPSGMPTCRCPTGFTGPKCTQQV--CAG-YCANNSTC--TVNQGNQPQCRCLPGFLGD- 4301
Query: 233 KYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNCPTKS 292
C C C C C C + G C++N + +
Sbjct: 4302 -RCQ-YRQC-SGYCENFGTCQMAADGSRQCRCTAYFEG--------SRCEVNKCSRCLEG 4350
Query: 293 TVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQK 352
G C C + G C +CT + EC C
Sbjct: 4351 ACVVNKQSGDVTCNCTD---------GRVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPP 4401
Query: 353 GYVG 356
G
Sbjct: 4402 HMTG 4405
Score = 63.5 bits (153), Expect = 2e-09
Identities = 198/949 (20%), Positives = 315/949 (33%), Gaps = 188/949 (19%)
Query: 734 GPDCNQCPGGFSNP-----CSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRC 788
GP CPG C G+ CAD G I S C D ++ +
Sbjct: 2775 GPSSFSCPGTHVCVPERWLCDGDKDCAD---GADESIAAGCLYNSTC----DDREFMCQ- 2826
Query: 789 NKKCLCVHGTCNNRIDSDGACLTGTCRDGS-AGRLCDKQTSACGPYVQFCHIHATCEYSN 847
N++C+ H C++ D C DGS C+ T CGP E+
Sbjct: 2827 NRQCIPKHFVCDHDRD---------CADGSDESPECEYPT--CGP----------SEFRC 2865
Query: 848 GTASCICKAGYEGDGTL-CSEMDPCTGLTPGGCSRNAECIKTGT---GTHTCVCQQGWTG 903
C+ +E DG C + P S+ +C + + CV +
Sbjct: 2866 ANGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCN 2925
Query: 904 NGRDCSE--------INNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR--GNGIDCEP 953
DC + IN CL GC + L +G +C C+ GFR +G C
Sbjct: 2926 GQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIG---FKCRCRPGFRLKDDGRTCAD 2982
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE---GDGFLCYGNAAVELSFLSEAAIF 1010
+ C P + + G + C+C EGY GD C +++ F
Sbjct: 2983 VDEC----STTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSC--------KAVTDEEPF 3030
Query: 1011 NRWINNASLQPTLSATSNLTVLVPSQQATEDMDQDEKS---FWLSQSNIPALI-KYHMLL 1066
+ N L+ SN T+L +D D + +W + ++I + H+
Sbjct: 3031 LIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNG 3090
Query: 1067 GTYRVADLQTLSSSDMLATSLQGNFLHLAKVDGNITIEGASIVDGDNAATNGVIHIINKV 1126
+V LS+ D LA G L+ G TIE + + N A V +++
Sbjct: 3091 SNVQVLHRTGLSNPDGLAVDWVGGNLYWCD-KGRDTIEVSKL----NGAYRTV--LVSSG 3143
Query: 1127 LVPQRRLTGSLPNLLMRLEQMPDYSIFRGYIIQYNLANAIEAADAYTVFAPNNNAIENYI 1186
L R L + N + D+S+ I + + + + T N +Y+
Sbjct: 3144 LREPRALVVDVQNGYLYWTDWGDHSL----IGRIGMDGSSRSVIVDTKITWPNGLTLDYV 3199
Query: 1187 REKKVLSLEEDVLRYHVVLEEKLLKNDLHNGMHRETMLG--FSYFLSFFLHNDQLYVNE- 1243
E+ Y E ++ +G +R +L + + L D +Y +
Sbjct: 3200 TER----------IYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDW 3249
Query: 1244 --APINYTNVATDKG---VIHGLGKVLE------IQKNRCDNNDTTIIRGRCRTC----- 1287
IN + T +I L + ++ +++ N+ + G C
Sbjct: 3250 ETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSP 3309
Query: 1288 --SSELTCPFGTKSLGNEKRRCI---YTSYFMGRRTLFIGCQPKCVRTVITRECCAGFFG 1342
+ CP LG++ R C+ S F+ + I KC T + C
Sbjct: 3310 GGGHKCACPTNF-YLGSDGRTCVSNCTASQFVCKNDKCIPFWWKC----DTEDDCGDHSD 3364
Query: 1343 -----PQCQPCPGNAQ---NVCFGNGICLDGVNGTGVCECGEGFSGTACE--TCTEGKYG 1392
P+ + PG Q +C DG N +C + C+ C ++
Sbjct: 3365 EPPDCPEFKCRPGQFQCSTGICTNPAFICDGDN-----DCQDNSDEANCDIHVCLPSQF- 3418
Query: 1393 IHCDQACSCVHG--RCN-QGPLGDGSCDCDVGWRGVHCDNATTEDN---CNGT------- 1439
C C+ G RCN Q GDG + D C T N C+ T
Sbjct: 3419 -KCTNTNRCIPGIFRCNGQDNCGDGEDERD-------CPEVTCAPNQFQCSITKRCIPRV 3470
Query: 1440 --CHTSANCLTNSDGTASC---KCAAG---FQGNGTICTAINAC----EISNGGCSAKAD 1487
C +C+ SD A+C C + +G A C + +G K +
Sbjct: 3471 WVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEE 3530
Query: 1488 CKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYT 1547
C T CK N C+ CD + +C G N +C P
Sbjct: 3531 CDERTCEPYQFRCKN------------NRCVPGRWQCDYDNDC---GDNSDEESCTPRPC 3575
Query: 1548 GDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCR 1596
+ + C+ C C G E+ CT P D F C+
Sbjct: 3576 SESEFSCANGRCIAGRWKCDGDHDC-ADGSDEKDCT--PRCDMDQFQCK 3621
Score = 61.6 bits (148), Expect = 9e-09
Identities = 62/228 (27%), Positives = 80/228 (35%), Gaps = 47/228 (20%)
Query: 726 PKC-CKGFY-GPDC--NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQC--QFCS 779
PKC C+ Y G C +QC C G CA S G TC C GF G +C Q C+
Sbjct: 4218 PKCRCQPRYTGDKCELDQC----WEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCA 4273
Query: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI 839
C C T N CL G D R C +C
Sbjct: 4274 G------YCANNSTC---TVNQGNQPQCRCLPGFLGDRCQYRQCS----------GYCEN 4314
Query: 840 HATCEY-SNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQ 898
TC+ ++G+ C C A +EG E++ C+ G C N + +G TC C
Sbjct: 4315 FGTCQMAADGSRQCRCTAYFEGSR---CEVNKCSRCLEGACVVNKQ-----SGDVTCNCT 4366
Query: 899 QGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRG 946
G + L G C + SC EC+C G
Sbjct: 4367 DG---------RVAPSCLTCVGHCSNGGSCTMNSKMMPECQCPPHMTG 4405
Score = 60.1 bits (144), Expect = 3e-08
Identities = 49/193 (25%), Positives = 70/193 (36%), Gaps = 48/193 (24%)
Query: 1887 GGRCDTFTTFDASGECGSCVNTPS------CPR-WSKPKGVKQKCLYNLPFKRNL---EG 1936
G +C+ ++ G+C +PS CP ++ PK +Q C +G
Sbjct: 4228 GDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQG 4287
Query: 1937 CRERCSLVIQIPRCCKGYFGRDCQ--ACPGGPDAPCNNRGVCLDQYSATGECKCNTGFNG 1994
+ +C RC G+ G CQ C G C N G C + +C+C F G
Sbjct: 4288 NQPQC-------RCLPGFLGDRCQYRQCSGY----CENFGTCQMAADGSRQCRCTAYFEG 4336
Query: 1995 TACEM-----------------------CWPGRFGPDCLPC--GCSDHGQCDDGITGSGQ 2029
+ CE+ C GR P CL C CS+ G C +
Sbjct: 4337 SRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCTMNSKMMPE 4396
Query: 2030 CLCETGWTGPSCD 2042
C C TGP C+
Sbjct: 4397 CQCPPHMTGPRCE 4409
Score = 57.0 bits (136), Expect = 2e-07
Identities = 59/243 (24%), Positives = 80/243 (32%), Gaps = 41/243 (16%)
Query: 741 PGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCN 800
PG + C G C + C C+ + G +C+ +C + C GTC
Sbjct: 4197 PGTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCEL--------DQCWEHCR-NGGTC- 4246
Query: 801 NRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGT-ASCICKAGYE 859
S T C G G C +Q A +C ++TC + G C C G+
Sbjct: 4247 --AASPSGMPTCRCPTGFTGPKCTQQVCA-----GYCANNSTCTVNQGNQPQCRCLPGFL 4299
Query: 860 GDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSA 919
GD + C+G C C G+ C C + G+ E+N C
Sbjct: 4300 GDR---CQYRQCSGY----CENFGTCQMAADGSRQCRCTAYFEGSR---CEVNKCSRCLE 4349
Query: 920 GGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWS 979
G C N G C C G SCL G C SC S +
Sbjct: 4350 GACVVNKQ-----SGDVTCNCTDG--------RVAPSCLTCVGHCSNGGSCTMNSKMMPE 4396
Query: 980 CVC 982
C C
Sbjct: 4397 CQC 4399
Score = 55.8 bits (133), Expect = 5e-07
Identities = 51/211 (24%), Positives = 79/211 (37%), Gaps = 35/211 (16%)
Query: 797 GTCNNRIDSDGACLTGT-------CRDGSAGRLCDKQTSACGPYVQFCHIHATCEYS-NG 848
GTCN + + G+C C+ G C+ C + C TC S +G
Sbjct: 4198 GTCNLQCFNGGSCFLNARRQPKCRCQPRYTGDKCE--LDQCWEH---CRNGGTCAASPSG 4252
Query: 849 TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDC 908
+C C G+ G C++ + G C+ N+ C C C G+ G D
Sbjct: 4253 MPTCRCPTGFTGPK--CTQQ-----VCAGYCANNSTCTVNQGNQPQCRCLPGFLG---DR 4302
Query: 909 SEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLA 968
+ C +G C + +C G +C C F G+ + + CLE G C
Sbjct: 4303 CQYRQC----SGYCENFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSRCLE--GAC---- 4352
Query: 969 SCQSTSSGVWSCVCQEGYEGDGFL-CYGNAA 998
+ SG +C C +G L C G+ +
Sbjct: 4353 -VVNKQSGDVTCNCTDGRVAPSCLTCVGHCS 4382
Score = 50.1 bits (118), Expect = 3e-05
Identities = 55/214 (25%), Positives = 83/214 (38%), Gaps = 56/214 (26%)
Query: 1963 PGG---PDAPCNNRGVCLD-QYSATGECKCNTGFNGTACE----MCWPGRFGPDCLPCGC 2014
PGG + C G+C+ ++ G+ C + +CE +C P + GC
Sbjct: 1059 PGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPS------VKFGC 1112
Query: 2015 SDHGQC-DDGITGSGQCLCETGWTGPSCDTQAVLP---------AVCTPP---CSAHATC 2061
D +C G CE +C++ A P +VC PP C + C
Sbjct: 1113 KDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDC 1172
Query: 2062 ----KENNTCE-CNLDY----------EGDGITCTVV--------DFCKQDNGGCAKVAR 2098
E C+ C+L+ G+GI C+ + Q CAK +
Sbjct: 1173 GDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLK 1232
Query: 2099 CSQKGTK----VSCSCQKGY--KGDGHSCTEIDP 2126
CSQK + V CSC +G+ + DG SC +DP
Sbjct: 1233 CSQKCDQNKFSVKCSCYEGWVLEPDGESCRSLDP 1266
Score = 47.0 bits (110), Expect = 2e-04
Identities = 67/262 (25%), Positives = 93/262 (35%), Gaps = 48/262 (18%)
Query: 1271 RCDNNDTTIIRGRCRT----CSSELTCPFGT--KSLGNEKRRCIYTSYFMGRRTLFIGCQ 1324
RCD + G C C ++ C G+ ++ G R C F TL C+
Sbjct: 3612 RCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDE-FQCNNTL---CK 3667
Query: 1325 PKCVRTVITREC----------CAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCEC 1374
P + +C CA F P +P VC G DG + C
Sbjct: 3668 PLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTD-----NC 3722
Query: 1375 GEGFSGTACET-------CTEGKYGIHCDQACSCVHGRCNQ-GPLGDGSC--DCDVGWRG 1424
G+G CE C + K + +Q C RCN GDGS DC + +
Sbjct: 3723 GDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKL 3782
Query: 1425 VHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ--GNGTICTAINACEISNGGC 1482
C AT C A C+ ++ A C C +GF C IN C + G C
Sbjct: 3783 TSC--ATNA----SICGDEARCV-RTEKAAYCACRSGFHTVPGQPGCQDINEC-LRFGTC 3834
Query: 1483 SAKADCKRTTPGRRVCTCKAGY 1504
S + T G +C+C +
Sbjct: 3835 SQLCN---NTKGGHLCSCARNF 3853
Score = 45.8 bits (107), Expect = 5e-04
Identities = 67/290 (23%), Positives = 97/290 (33%), Gaps = 86/290 (29%)
Query: 664 RCDETKREMKLGTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCAR------ 717
RCD + + K G C+ + W RC A+++ C+ GS + C
Sbjct: 3612 RCDMDQFQCKSGHCIP---LRW-RCDADAD--------CMD----GSDEEACGTGVRTCP 3655
Query: 718 ----YCNATVKIPKCCKGFYGPDCNQ-------------CPGGFSNPCSGNGQCADSLGG 760
CN T+ P K DC CP C + C +G
Sbjct: 3656 LDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCL-WIGR 3714
Query: 761 --NGTCICEEGFQGSQCQ-------FCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLT 811
+GT C +G C+ C D ++ R N++CL CN D
Sbjct: 3715 QCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCR-NQRCLSSSLRCNMFDD------- 3766
Query: 812 GTCRDGSAGRLC--DKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMD 869
C DGS C D + ++C C A C + A C C++G+
Sbjct: 3767 --CGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFH---------- 3814
Query: 870 PCTGLTPG--GCSRNAECIKTGT---------GTHTCVCQQGWTGNGRDC 908
PG GC EC++ GT G H C C + + C
Sbjct: 3815 ----TVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTC 3860
Score = 45.1 bits (105), Expect = 0.001
Identities = 38/167 (22%), Positives = 55/167 (32%), Gaps = 34/167 (20%)
Query: 1447 LTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSA---------------------- 1484
+TN C+ +G +CT N + NG C
Sbjct: 4147 VTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFN 4206
Query: 1485 KADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLP 1544
C + C C+ YTGD E++ C E+ C C + C C
Sbjct: 4207 GGSCFLNARRQPKCRCQPRYTGDK---CELDQCWEH---CRNGGTCAASPSGMPTCRCPT 4260
Query: 1545 AYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGD 1591
+T G CT VC G C+ + C + C C P ++GD
Sbjct: 4261 GFT--GPKCTQ-QVCA---GYCANNSTCTVNQGNQPQCRCLPGFLGD 4301
Score = 44.3 bits (103), Expect = 0.002
Identities = 77/298 (25%), Positives = 112/298 (37%), Gaps = 60/298 (20%)
Query: 712 KSGCARYCNATVKIPKCCKGFYGPDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQ 771
++GC+ C++T KC G P+ C G N C G +D N T Q
Sbjct: 1008 EAGCSHSCSSTQF--KCNSGRCIPEHWTCDG--DNDC---GDYSDETHANCTN------Q 1054
Query: 772 GSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACG 831
++ +++ R + C+ + C+ D C D S + C+ T C
Sbjct: 1055 ATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTD---------CMDSSDEKSCEGVTHVCD 1105
Query: 832 PYVQFCHIHATCEYSNGTASCICKAGY-EGDGTL--CSEMDPCTGLT----PGGCSRNAE 884
P V+F C+ S A CI KA +GD S+ + C L C+ N
Sbjct: 1106 PSVKF-----GCKDS---ARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTS 1157
Query: 885 -CI---KTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQN-ECE 939
C+ K G C G+G D E+ + + GGC N S V PG+ C
Sbjct: 1158 VCLPPDKLCDGNDDC-------GDGSDEGELCDQCSLNNGGCSHNCS---VAPGEGIVCS 1207
Query: 940 CKKGFR--GNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGY--EGDGFLC 993
C G + C+ + C + KC C V C C EG+ E DG C
Sbjct: 1208 CPLGMELGPDNHTCQIQSYCAKHL-KCS--QKCDQNKFSV-KCSCYEGWVLEPDGESC 1261
Score = 43.9 bits (102), Expect = 0.002
Identities = 81/380 (21%), Positives = 113/380 (29%), Gaps = 116/380 (30%)
Query: 88 RHICRKDYLQ---PRCCPGRW----GPDCIECPGGAGSPCNGRG------SCAEG--MEG 132
+H C D + RC P RW DC + + C+ R SCA G +
Sbjct: 892 QHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPI 951
Query: 133 NGTCSCQEGFGGTACET---------------------------CADDNLFGPS-----C 160
+ TC + G + E+ C +DN G + C
Sbjct: 952 SWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGC 1011
Query: 161 SSVCNCVHGVCNSG--------LDGDGTCECYSAYTGPKC----DKPIPEC--------- 199
S C+ CNSG DGD C YS T C +P C
Sbjct: 1012 SHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRL 1071
Query: 200 AALLCPENSRCSPSTE-----DENKLE-------------CKCLPNYRGDGKYCDPINPC 241
L P RC T+ DE E CK CD N C
Sbjct: 1072 DGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDC 1131
Query: 242 LRKICHPHAHCTYLGPNRHSCT------------------CQEGYRGDGQVCLPVDPCQI 283
+ P H C C +G +G++C D C +
Sbjct: 1132 EDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDG-SDEGELC---DQCSL 1187
Query: 284 NFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAP 343
N G C +V +G C C + C + C C + + +
Sbjct: 1188 NNGGCSHNCSVAPGEG---IVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFS- 1243
Query: 344 GRTECICQKGYV--GDGLTC 361
+C C +G+V DG +C
Sbjct: 1244 --VKCSCYEGWVLEPDGESC 1261
Score = 43.9 bits (102), Expect = 0.002
Identities = 36/133 (27%), Positives = 43/133 (32%), Gaps = 24/133 (18%)
Query: 239 NPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPV-----DPCQINFGNCPTK-- 291
NPC RK C L P+ CTC G R D C+PV P G C +
Sbjct: 4149 NPCDRKKCE---WLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCF 4205
Query: 292 -STVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKSD---NPCHRNANCTTVAPGRTE 347
C + Q C C+ Y D C+ D C C G
Sbjct: 4206 NGGSCFLNARRQPKCRCQPRYTG----------DKCELDQCWEHCRNGGTCAASPSGMPT 4255
Query: 348 CICQKGYVGDGLT 360
C C G+ G T
Sbjct: 4256 CRCPTGFTGPKCT 4268
Score = 42.7 bits (99), Expect = 0.005
Identities = 65/298 (21%), Positives = 100/298 (33%), Gaps = 60/298 (20%)
Query: 89 HICRKDYLQPRCCPGRWGPDCIECPGGAGSPCNGRGSC-AEGMEGNGTCSCQEGFGGTAC 147
H C + C P R D +C G P R A+ M+G+ +C GT
Sbjct: 3598 HDCADGSDEKDCTP-RCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC-----GTGV 3651
Query: 148 ETCADDNLFGPSCSS-VCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPE 206
TC D C++ +C + C DG+ C G D+ ECA +CP
Sbjct: 3652 RTCPLDEF---QCNNTLCKPLAWKC----DGEDDC-------GDNSDENPEECARFVCPP 3697
Query: 207 NS--RCSPSTEDENKLECKCLPNYRGDGKYCDPINPC----LRKICH-PHAHCTYLGPNR 259
N RC +N C + G+ CD + C + C P AH T+ +
Sbjct: 3698 NRPFRC------KNDRVCLWI------GRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKK 3745
Query: 260 HSCTCQEGYRGDGQVCLPVDPC-----------QINFGNCPTKSTVCKYDG-----PGQS 303
+ C D C +C T +++C + +
Sbjct: 3746 EFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAA 3805
Query: 304 HCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTC 361
+C C+ + GC + C C + N T G C C + ++ TC
Sbjct: 3806 YCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNT---KGGHLCSCARNFMKTHNTC 3860
Score = 42.4 bits (98), Expect = 0.006
Identities = 71/290 (24%), Positives = 97/290 (33%), Gaps = 66/290 (22%)
Query: 101 CPGRW-GPDCIECPGGAGSP-----CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDN 154
C G+ GP CPG C+G CA+G + + C TC DD
Sbjct: 2769 CEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYN------STC-DDR 2821
Query: 155 LFGPSCSS-VCNCVHGVCNSGLD-GDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSP 212
F C + C H VC+ D DG+ E P+C+ P + C N RC
Sbjct: 2822 EF--MCQNRQCIPKHFVCDHDRDCADGSDE------SPECEYPTCGPSEFRCA-NGRCLS 2872
Query: 213 STEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYR--- 269
S + E E C D P NP HCT H C +
Sbjct: 2873 SRQWECDGENDC-----HDQSDEAPKNP----------HCT---SQEHKCNASSQFLCSS 2914
Query: 270 ----GDGQVCLPVDPCQINFGNCPTKSTVC---KYDGPGQS--------HCECKEHYQNF 314
+ +C D C + C K G Q C C+ ++
Sbjct: 2915 GRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFRLK 2974
Query: 315 VPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYV---GDGLTC 361
G C+ D C + PC + T G +C+C +GY GD +C
Sbjct: 2975 DDGRTCADVDECSTTFPCSQRCINT---HGSYKCLCVEGYAPRGGDPHSC 3021
Score = 42.4 bits (98), Expect = 0.006
Identities = 41/176 (23%), Positives = 51/176 (28%), Gaps = 33/176 (18%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCS----------CQEGFGGTACET 149
C G CP G P + CA N TC+ C GF G C+
Sbjct: 4246 CAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQY 4305
Query: 150 CADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD-KPIPECAALLCPENS 208
CS C G C DG C C + + G +C+ C C N
Sbjct: 4306 --------RQCSGYCE-NFGTCQMAADGSRQCRCTAYFEGSRCEVNKCSRCLEGACVVNK 4356
Query: 209 RCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTC 264
+ T C C DG+ C+ C CT C C
Sbjct: 4357 QSGDVT-------CNCT-----DGRVAPSCLTCVGH-CSNGGSCTMNSKMMPECQC 4399
Score = 40.0 bits (92), Expect = 0.029
Identities = 36/140 (25%), Positives = 49/140 (35%), Gaps = 30/140 (21%)
Query: 1473 NACEISNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINP-------------- 1516
N C ++NGGCS+ TPG R C C DG+ CL NP
Sbjct: 805 NKCRVNNGGCSSLC---LATPGSRQCACAEDQVLDADGVTCL-ANPSYVPPPQCQPGEFA 860
Query: 1517 -----CLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFAI 1571
C++ CD + +C ++A C + N C+ C
Sbjct: 861 CANSRCIQERWKCDGDNDCLDNS-DEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGDND 919
Query: 1572 C-NHTGQVERTC---TCKPN 1587
C N + TC TC PN
Sbjct: 920 CGNSEDESNATCSARTCPPN 939
Score = 40.0 bits (92), Expect = 0.029
Identities = 50/210 (23%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
Query: 1970 CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDHGQCDDGITGSGQ 2029
C++ C D + EC+ T C P F C S +CD G
Sbjct: 2837 CDHDRDCADGSDESPECEYPT---------CGPSEFRCANGRCLSSRQWECD----GEND 2883
Query: 2030 CLCETGWT--GPSCDTQ-----AVLPAVCTPP-CSAHAT-CKENNTCECNLDYEGDGITC 2080
C ++ P C +Q A +C+ C A A C + C + D G C
Sbjct: 2884 CHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERG----C 2939
Query: 2081 TVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGY--KGDGHSCTEIDPCADGLNGGCHEH 2138
+ + + GC++ + G K C C+ G+ K DG +C ++D C+ C +
Sbjct: 2940 HINECLSRKLSGCSQDCEDLKIGFK--CRCRPGFRLKDDGRTCADVDECSTTF--PCSQR 2995
Query: 2139 ATCKMTGPGKHKCECKSHYV---GDGLNCE 2165
+ G +KC C Y GD +C+
Sbjct: 2996 C---INTHGSYKCLCVEGYAPRGGDPHSCK 3022
Score = 38.1 bits (87), Expect = 0.11
Identities = 47/216 (21%), Positives = 70/216 (32%), Gaps = 43/216 (19%)
Query: 739 QCPGGFSNP----CSGNGQCADSLGGNGTCICEEGFQGSQC-QFCSDPNK-YGPRCNKKC 792
QC P C G C D+ N +C +F PN+ + + ++ C
Sbjct: 3660 QCNNTLCKPLAWKCDGEDDCGDNSDENP----------EECARFVCPPNRPFRCKNDRVC 3709
Query: 793 LCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDK---QTSACGPYVQFCHIHATCEYSNGT 849
L + C+ T C DG+ C+ T+ C +F + C S+
Sbjct: 3710 LWIGRQCDG---------TDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLR 3760
Query: 850 ASCICKAGYEGDGTLCSEMDPCTGLTPGG--CSRNAECIKTGTGTHTCVCQQGWTGNGRD 907
+ G D CS T C A C++T + C C+ G+
Sbjct: 3761 CNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAY-CACRSGFH----- 3814
Query: 908 CSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKG 943
+P GC D CL G C KG
Sbjct: 3815 -------TVPGQPGCQDINECLRFGTCSQLCNNTKG 3843
Score = 37.7 bits (86), Expect = 0.15
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 748 CSGNGQCADSLGGNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDG 807
C G C D IC + + +CQ PN++ + C+ + CN D
Sbjct: 47 CDGERDCPDG-SDEAPEICPQS-KAQRCQ----PNEHNCLGTELCVPMSRLCNGVQD--- 97
Query: 808 ACLTGTCRDGS-AGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCS 866
C DGS G C + C C H T C + DG C
Sbjct: 98 ------CMDGSDEGPHCRELQGNCSRLG--CQHHCVPTLDGPTCYCNSSFQLQADGKTCK 149
Query: 867 EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGW--TGNGRDCSEIN 912
+ D C+ G CS+ C T G+ C C +G+ + R C N
Sbjct: 150 DFDECS--VYGTCSQ--LCTNT-DGSFICGCVEGYLLQPDNRSCKAKN 192
Score = 37.4 bits (85), Expect = 0.19
Identities = 61/273 (22%), Positives = 92/273 (33%), Gaps = 74/273 (27%)
Query: 1386 CTEGKYGIHCDQACSCVHGRCNQGPL--------GDGSCDCDVGWRGVHCDNATTEDNCN 1437
C + C +CS +CN G GD C +C N T
Sbjct: 1002 CGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRP--P 1059
Query: 1438 GTCHT--------------------SANCLTNSDGTA--------------SCKCAAGFQ 1463
G CHT +C+ +SD + CK +A
Sbjct: 1060 GGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCI 1119
Query: 1464 GNGTICTAINACEISNG--GCSAKA------DCKRTT----PGRRVC----TCKAGYTGD 1507
+C N CE ++ C + A C T P ++C C G + +
Sbjct: 1120 SKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDG-SDE 1178
Query: 1508 GIVCLEINPCLENHGGCDKNAECTQTGPNQAACNC-LPAYTG-DGKVCTLINVCLTKNGG 1565
G +C + C N+GGC N C+ C+C L G D C + + C K+
Sbjct: 1179 GELC---DQCSLNNGGCSHN--CSVAPGEGIVCSCPLGMELGPDNHTCQIQSYC-AKHLK 1232
Query: 1566 CSEFAICNHTGQVERTCTCKPNYI--GDGFTCR 1596
CS+ N + C+C ++ DG +CR
Sbjct: 1233 CSQKCDQN---KFSVKCSCYEGWVLEPDGESCR 1262
Score = 37.4 bits (85), Expect = 0.19
Identities = 65/319 (20%), Positives = 98/319 (30%), Gaps = 63/319 (19%)
Query: 1284 CRTCSSELTCPFGTKSLGNEKRR---CIYTSYFMGRRTLFIGCQPKCVRTVITRECCAGF 1340
C S E+ C +G + R CI S R F+ C+ + C+ +
Sbjct: 2591 CGDGSDEIPCNKTACGVGEFRCRDGTCIGNS---SRCNQFVDCEDASDEMNCSATDCSSY 2647
Query: 1341 F-----GPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHC 1395
F G QPC ++C+ DG N +CG+ C + ++
Sbjct: 2648 FRLGVKGVLFQPC--ERTSLCYAPSWVCDGAN-----DCGDYSDERDCPGVKRPRCPLNY 2700
Query: 1396 DQACSCVHGRCNQGPLG---DGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG 1452
+C GRC P+ D DC+ G HC+ +E H + DG
Sbjct: 2701 ---FACPSGRCI--PMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDG 2755
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
+ C G A C+ T G +C +
Sbjct: 2756 SDDC----------------------GDGSDEAAHCEGKTCGPSSFSCPGTHV------- 2786
Query: 1513 EINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLIN-VCLTKNGGCSEFAI 1571
C+ CD + +C A CL T D + N C+ K+ C
Sbjct: 2787 ----CVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRD 2842
Query: 1572 CNHTGQVERTC---TCKPN 1587
C C TC P+
Sbjct: 2843 CADGSDESPECEYPTCGPS 2861
Score = 37.0 bits (84), Expect = 0.25
Identities = 58/249 (23%), Positives = 80/249 (32%), Gaps = 63/249 (25%)
Query: 1956 GRDCQACPGG------PDAPCNNRGVCLDQYSATGECKC--NTGFNGTACE--MCWPGRF 2005
G D +AC G + CNN + GE C N+ N C +C P R
Sbjct: 3641 GSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPPNR- 3699
Query: 2006 GPDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDT-----QAVLPAVCTPPCSAHAT 2060
P C + C W G CD C PP +
Sbjct: 3700 -----PFRCKNDRVCL--------------WIGRQCDGTDNCGDGTDEEDCEPPTAHTTH 3740
Query: 2061 CKE-------NNTC-----ECNL-DYEGDGIT---CTV---VDFCKQDNGGCAKVARCSQ 2101
CK+ N C CN+ D GDG C++ + C + C ARC +
Sbjct: 3741 CKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEEDCSIDPKLTSCATNASICGDEARCVR 3800
Query: 2102 KGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKM---TGPGKHKCECKSHYV 2158
C+C+ G+ H+ C D C TC G H C C +++
Sbjct: 3801 TEKAAYCACRSGF----HTVPGQPGCQD--INECLRFGTCSQLCNNTKGGHLCSCARNFM 3854
Query: 2159 GDGLNCEPE 2167
C+ E
Sbjct: 3855 KTHNTCKAE 3863
Score = 36.2 bits (82), Expect = 0.42
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 1557 NVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIG-DGFTCR 1596
NVC NGGC + +C + G+ +R C C + DG +CR
Sbjct: 2157 NVCAVANGGCQQ--LCLYRGRGQRACACAHGMLAEDGASCR 2195
Score = 36.2 bits (82), Expect = 0.42
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 19/88 (21%)
Query: 117 GSPC--NGRGSCAEG------MEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH 168
GS C N C EG G+ TC+C +G +C TC G SC+
Sbjct: 4336 GSRCEVNKCSRCLEGACVVNKQSGDVTCNCTDGRVAPSCLTCVGHCSNGGSCT------- 4388
Query: 169 GVCNSGLDGDGTCECYSAYTGPKCDKPI 196
NS + + C+C TGP+C++ +
Sbjct: 4389 --MNSKMMPE--CQCPPHMTGPRCEEHV 4412
Score = 35.4 bits (80), Expect = 0.72
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 12/95 (12%)
Query: 2086 CKQDNGGCAKVA---RCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADGLNGGCHEHAT 2140
C++ G C+++ C +C C ++ DG +C + D C+ + G C + T
Sbjct: 108 CRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECS--VYGTCSQLCT 165
Query: 2141 CKMTGPGKHKCECKSHYV--GDGLNCEPEQLPIDR 2173
G C C Y+ D +C+ + P+DR
Sbjct: 166 ---NTDGSFICGCVEGYLLQPDNRSCKAKNEPVDR 197
Score = 35.0 bits (79), Expect = 0.95
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 26/148 (17%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVN-GTGVCECGEGFS-GTACETCTEGKYG 1392
E C +CQP N C G +C+ GV +C +G G C
Sbjct: 62 EICPQSKAQRCQPNEHN----CLGTELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSR 117
Query: 1393 IHCDQACSCVHGRCNQGPLGDG-SCDCDVGWRGVHCDNATTED--NCN--GTCHTSANCL 1447
+ C C P DG +C C+ ++ + D T +D C+ GTC +
Sbjct: 118 LGCQHHCV---------PTLDGPTCYCNSSFQ-LQADGKTCKDFDECSVYGTC---SQLC 164
Query: 1448 TNSDGTASCKCAAGF--QGNGTICTAIN 1473
TN+DG+ C C G+ Q + C A N
Sbjct: 165 TNTDGSFICGCVEGYLLQPDNRSCKAKN 192
Score = 34.3 bits (77), Expect = 1.6
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 19/74 (25%)
Query: 2132 NGGCHEHATCKMTGPGKHKCECKSHYV--GDGLNC--EPEQLPI------------DRCL 2175
NGGC + C T PG +C C V DG+ C P +P RC+
Sbjct: 811 NGGCS--SLCLAT-PGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCI 867
Query: 2176 QDNGQCHADAKCVD 2189
Q+ +C D C+D
Sbjct: 868 QERWKCDGDNDCLD 881
Score = 34.3 bits (77), Expect = 1.6
Identities = 70/296 (23%), Positives = 98/296 (33%), Gaps = 73/296 (24%)
Query: 664 RCDETKREMKLGTCVSCSLVYW-----------SRCPANSEPTALFTHRCVYSGRFGSLK 712
RC +T R+ G CVS L W P N + RC G+
Sbjct: 2565 RCKKTFRQCSNGRCVSNML--WCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGN-S 2621
Query: 713 SGCARY--CNATVKIPKCCKGFYGPDCNQ-----CPGGFSNPCSGNGQC-ADSLGGNGTC 764
S C ++ C C DC+ G PC C A S +G
Sbjct: 2622 SRCNQFVDCEDASDEMNCS----ATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGAN 2677
Query: 765 ICEEGFQGSQCQFCSDPNKYGPRC--------NKKCLCVHGTCNNRIDSDGACLTGTCRD 816
C + C P PRC + +C+ + TC+ D C
Sbjct: 2678 DCGDYSDERDC-----PGVKRPRCPLNYFACPSGRCIPMSWTCDKEDD---------CEH 2723
Query: 817 GSAGRLCDKQTSACGPYVQF-CHIHATCEYS---NGTASCICKAGYEGDGTLCSEMDPCT 872
G C+K S QF C H +G+ C GDG+ E C
Sbjct: 2724 GEDETHCNKFCSEA----QFECQNHRCISKQWLCDGSDDC-------GDGS--DEAAHCE 2770
Query: 873 GLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASC 928
G T G S + GTH CV ++ +DC++ + + A GC N++C
Sbjct: 2771 GKTCGPSSFSCP------GTHVCVPERWLCDGDKDCADGADESI--AAGCLYNSTC 2818
Score = 33.5 bits (75), Expect = 2.8
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 1545 AYTGDGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYI-GDGFTCR 1596
A D C L + C NGGC + + H G V C+C+ I D TCR
Sbjct: 2469 AVANDTNSCEL-SPCRINNGGCQDLCLLTHQGHV--NCSCRGGRILQDDLTCR 2518
Score = 32.3 bits (72), Expect = 6.1
Identities = 61/275 (22%), Positives = 86/275 (31%), Gaps = 78/275 (28%)
Query: 1348 CPGNA----QNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVH 1403
CP + N C N DG N G E E + + TC ++ SC
Sbjct: 895 CPSDRFKCENNRCIPNRWLCDGDNDCGNSE-DESNATCSARTCPPNQF--------SCAS 945
Query: 1404 GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKC----- 1458
GRC + W TC +C SD +ASC
Sbjct: 946 GRC-----------IPISW----------------TCDLDDDCGDRSDESASCAYPTCFP 978
Query: 1459 AAGFQGNGTICTAIN-ACEISN--GGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEIN 1515
F N C IN C+ N G S +A C + + C +G
Sbjct: 979 LTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQF-KCNSG------------ 1025
Query: 1516 PCLENHGGCDKNAECTQTGPNQAACNCLPAYT-------GDGKVCTLINVCLTKNGGCSE 1568
C+ H CD + +C ++ NC T D C L +C+ C
Sbjct: 1026 RCIPEHWTCDGDNDCGDYS-DETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDG 1084
Query: 1569 FAICNHTGQVERTC-----TCKPNYIGDGFTCRGS 1598
C + E++C C P+ F C+ S
Sbjct: 1085 DTDCMDSSD-EKSCEGVTHVCDPSV---KFGCKDS 1115
Score = 32.3 bits (72), Expect = 6.1
Identities = 59/245 (24%), Positives = 79/245 (32%), Gaps = 49/245 (20%)
Query: 1970 CNNRGVCLDQ-YSATGECKCNTGFNGTACE--MCWPGRFGPD----CLP--CGCSDHGQC 2020
C N C+ + G+ C G + C C P +F C+P C C
Sbjct: 3420 CTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDC 3479
Query: 2021 DDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDY---EGDG 2077
DG C T T + + C P A C + C D E D
Sbjct: 3480 VDGSDEPANC---TQMTCGVDEFRCKDSGRCIP---ARWKCDGEDDCGDGSDEPKEECDE 3533
Query: 2078 ITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADG----LNG 2133
TC F ++N RC + G D SCT PC++ NG
Sbjct: 3534 RTCEPYQFRCKNN-------RCVPGRWQCDYDNDCGDNSDEESCTP-RPCSESEFSCANG 3585
Query: 2134 GCHEHATCKMTGPGKHKCECKSHYVGDGLN---CEPE------QLPIDRCLQDNGQCHAD 2184
C G+ KC+ H DG + C P Q C+ +C AD
Sbjct: 3586 RCIA---------GRWKCD-GDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDAD 3635
Query: 2185 AKCVD 2189
A C+D
Sbjct: 3636 ADCMD 3640
Score = 32.0 bits (71), Expect = 8.0
Identities = 37/152 (24%), Positives = 48/152 (31%), Gaps = 30/152 (19%)
Query: 1465 NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAG-YTGDGIVCLEIN-------- 1515
N T ++ C I+NGGC C T G C+C+ G D + C +N
Sbjct: 2472 NDTNSCELSPCRINNGGCQDL--CLLTHQGHVNCSCRGGRILQDDLTCRAVNSSCRAQDE 2529
Query: 1516 ------PCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGC-SE 1568
C+ CD C + P+Y + C NG C S
Sbjct: 2530 FECANGECINFSLTCDGVPHCKDKSDEK------PSYCNSRRCKKTFRQC--SNGRCVSN 2581
Query: 1569 FAICN---HTGQVERTCTCKPNYIGDG-FTCR 1596
CN G C G G F CR
Sbjct: 2582 MLWCNGADDCGDGSDEIPCNKTACGVGEFRCR 2613
>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
Length = 988
Score = 95.1 bits (235), Expect = 8e-19
Identities = 85/269 (31%), Positives = 106/269 (39%), Gaps = 52/269 (19%)
Query: 1344 QCQPCPGNAQNVCF-GNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCV 1402
+C PGN + CF G + DG N V EC + G C Q C
Sbjct: 90 ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGG--------------CQQICV-- 133
Query: 1403 HGRCNQGPLGDGSCDCDVGW----RGVHCDNATTED-NCNGTCHTSAN-CLTNSDGTASC 1456
+G C C G+ C + + E NC H A+ C G +C
Sbjct: 134 ------NAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRETPKGGVAC 187
Query: 1457 KCAAGFQ--GNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYT--GDGIVCL 1512
C GF N CT C NGGC + T P C C Y DG C+
Sbjct: 188 DCRPGFDLAQNQKDCTL--TCNYGNGGCQHSCEDTDTGP---TCGCHQKYALHSDGRTCI 242
Query: 1513 EINPCLENHGGCDKNAECTQTGPNQAACNCLPAYT--GDGKVCTLINVCLTKNGGCSEFA 1570
E C N+GGCD+ + T TG C+C +T DGK C IN CL NGGC F
Sbjct: 243 ET--CAVNNGGCDRTCKDTATG---VRCSCPVGFTLQPDGKTCKDINECLVNNGGCDHF- 296
Query: 1571 ICNHT-GQVERTCTCKPNY--IGDGFTCR 1596
C +T G E C C+ Y + D TC+
Sbjct: 297 -CRNTVGSFE--CGCRKGYKLLTDERTCQ 322
Score = 75.1 bits (183), Expect = 8e-13
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 18/180 (10%)
Query: 817 GSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPC-TGLT 875
G +G C CHI A C+ + + C+CK GY+G+G C ++D C
Sbjct: 24 GGSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYY 83
Query: 876 PGGCSRNAECIKTGTGTHTCVCQQGW--TGNGRDCSEINNCLLPSAGGCHDNASCLYVGP 933
GGC ECI G + C C G+ +G +C +++ C + GGC C+
Sbjct: 84 NGGCVH--ECINI-PGNYRCTCFDGFMLAHDGHNCLDVDEC-QDNNGGCQQ--ICVN-AM 136
Query: 934 GQNECECKKGF--RGNGIDC----EPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYE 987
G EC+C GF N C +C+ + C + C+ T G +C C+ G++
Sbjct: 137 GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHI--CRETPKGGVACDCRPGFD 194
Score = 72.0 bits (175), Expect = 7e-12
Identities = 56/195 (28%), Positives = 78/195 (40%), Gaps = 31/195 (15%)
Query: 1404 GRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ 1463
GR G GS D D C T + CH A C N+ + C C G++
Sbjct: 20 GRLAGGSGLPGSVDVD------ECSEGTDD------CHIDAIC-QNTPKSYKCLCKPGYK 66
Query: 1464 GNGTICTAINACE--ISNGGCSAKADCKRTTPGRRVCTCKAGY--TGDGIVCLEINPCLE 1519
G G C I+ CE NGGC + PG CTC G+ DG CL+++ C +
Sbjct: 67 GEGKQCEDIDECENDYYNGGCVHEC---INIPGNYRCTCFDGFMLAHDGHNCLDVDECQD 123
Query: 1520 NHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLIN------VCLTKNGGCSEFAICN 1573
N+GGC + C C + T I+ C+ K+ GC+ IC
Sbjct: 124 NNGGCQ---QICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH--ICR 178
Query: 1574 HTGQVERTCTCKPNY 1588
T + C C+P +
Sbjct: 179 ETPKGGVACDCRPGF 193
Score = 71.6 bits (174), Expect = 9e-12
Identities = 86/325 (26%), Positives = 117/325 (36%), Gaps = 79/325 (24%)
Query: 719 CNATVKIPKC-CKGFYGPDCNQCPGGFSNPCSG---NGQCAD---SLGGNGTCICEEGFQ 771
C T K KC CK Y + QC + C NG C ++ GN C C +GF
Sbjct: 50 CQNTPKSYKCLCKPGYKGEGKQCED--IDECENDYYNGGCVHECINIPGNYRCTCFDGFM 107
Query: 772 ----GSQCQFCSDPNKYGPRCNKKCLCVHG-----------------TCNNRIDSDGACL 810
G C + C + C+ G TC +R + C+
Sbjct: 108 LAHDGHNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCM 167
Query: 811 TGT------CRDGSAGRL-CDKQTSACGPYVQFCHIHA----TCEYSNG----------- 848
CR+ G + CD C P TC Y NG
Sbjct: 168 NKDHGCAHICRETPKGGVACD-----CRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDT 222
Query: 849 --TASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWT--GN 904
T C K DG C E + GGC R C T TG C C G+T +
Sbjct: 223 GPTCGCHQKYALHSDGRTCIET---CAVNNGGCDRT--CKDTATGVR-CSCPVGFTLQPD 276
Query: 905 GRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFR--GNGIDCEPITSC-LEQT 961
G+ C +IN CL+ + G H + + G EC C+KG++ + C+ I C E+T
Sbjct: 277 GKTCKDINECLVNNGGCDHFCRNTV----GSFECGCRKGYKLLTDERTCQDIDECSFERT 332
Query: 962 GKCHPLASCQSTSSGVWSCVCQEGY 986
C + S G + C+C GY
Sbjct: 333 --CDHIC---INSPGSFQCLCHRGY 352
Score = 70.5 bits (171), Expect = 2e-11
Identities = 72/309 (23%), Positives = 110/309 (35%), Gaps = 53/309 (17%)
Query: 91 CRKDYLQPRCCPGRWGPDCIECPGGAGSPC--------------------NGRGSCAE-- 128
C DY C +CI PG C + G C +
Sbjct: 78 CENDYYNGGCVH-----ECINIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQIC 132
Query: 129 -GMEGNGTCSCQEGFGGTACE-TCADDNLFGPSCSSVCN-CVHGVCNSGLDGDGTCECYS 185
G+ C C GF + + TC + G +C + + C H +C G C+C
Sbjct: 133 VNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAH-ICRETPKGGVACDCRP 191
Query: 186 AYTGPKCDKPIPECAALLCPENSRCSPSTED-ENKLECKCLPNY--RGDGKYCDPINPCL 242
+ + K +C N C S ED + C C Y DG+ C
Sbjct: 192 GFDLAQNQK---DCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVN 248
Query: 243 RKICHPHAHCTYLGPNRHSCTCQEGY--RGDGQVCLPVDPCQINFGNCP--TKSTVCKYD 298
C T G C+C G+ + DG+ C ++ C +N G C ++TV
Sbjct: 249 NGGCDRTCKDTATGVR---CSCPVGFTLQPDGKTCKDINECLVNNGGCDHFCRNTV---- 301
Query: 299 GPGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDG 358
G C C++ Y+ C D C + C + +PG +C+C +GY+ G
Sbjct: 302 --GSFECGCRKGYKLLTDERTCQDIDECSFERTCD---HICINSPGSFQCLCHRGYILYG 356
Query: 359 LTCYGNIME 367
T G++ E
Sbjct: 357 TTHCGDVDE 365
Score = 70.1 bits (170), Expect = 3e-11
Identities = 88/338 (26%), Positives = 130/338 (38%), Gaps = 68/338 (20%)
Query: 1886 LGGRCDTFTTFDASGEC---GSCVNTPS-----CPRWSKPKGVKQKCLYNLPFKRNLEGC 1937
L G D + + +C C NTP C K +G + + + GC
Sbjct: 28 LPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGC 87
Query: 1938 RERCSLVIQIP-----RCCKGYF-GRDCQACPGGPDAPCNNRG---VCLDQYSATGECKC 1988
C I IP C G+ D C + NN G +C++ + EC+C
Sbjct: 88 VHEC---INIPGNYRCTCFDGFMLAHDGHNCLDVDECQDNNGGCQQICVNAMGSY-ECQC 143
Query: 1989 NTGF----NGTACEMCWPGRFGPDCLPCGCSDHGQ---CDDGITGSGQCLCETGWTGPSC 2041
++GF N C G +C+ DHG C + G C C G+
Sbjct: 144 HSGFFLSDNQHTC--IHRSNEGMNCMN---KDHGCAHICRETPKGGVACDCRPGFD---- 194
Query: 2042 DTQAVLPAVCTPPCS-----AHATCKENNT---CECNLDY--EGDGITCTVVDFCKQDNG 2091
A CT C+ +C++ +T C C+ Y DG TC ++ C +NG
Sbjct: 195 --LAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTC--IETCAVNNG 250
Query: 2092 GCAKVARCSQKGTKVSCSCQKGY--KGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKH 2149
GC + C T V CSC G+ + DG +C +I+ C NGGC C+ T G
Sbjct: 251 GCDRT--CKDTATGVRCSCPVGFTLQPDGKTCKDINECLVN-NGGCDHF--CRNT-VGSF 304
Query: 2150 KCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC 2187
+C C+ Y + L +R QD +C + C
Sbjct: 305 ECGCRKGY---------KLLTDERTCQDIDECSFERTC 333
Score = 67.0 bits (162), Expect = 2e-10
Identities = 42/112 (37%), Positives = 55/112 (49%), Gaps = 13/112 (11%)
Query: 2075 GDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCA-DGLN 2132
G G+ +V VD C + C A C C C+ GYKG+G C +ID C D N
Sbjct: 25 GSGLPGSVDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYN 84
Query: 2133 GGC-HEHATCKMTGPGKHKCECKSHYV--GDGLNCEPEQLPIDRCLQDNGQC 2181
GGC HE C + PG ++C C ++ DG NC L +D C +NG C
Sbjct: 85 GGCVHE---C-INIPGNYRCTCFDGFMLAHDGHNC----LDVDECQDNNGGC 128
Score = 64.3 bits (155), Expect = 1e-09
Identities = 73/288 (25%), Positives = 107/288 (37%), Gaps = 60/288 (20%)
Query: 700 HRCVYSGRFG----SLKSGCARYCNATVKIPKCCKGFYGPD-----------CNQCPGGF 744
H C++ G + GCA C T K C G D CN GG
Sbjct: 154 HTCIHRSNEGMNCMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGC 213
Query: 745 SNPC------------------SGNGQCADSLG-GNGTC--ICEEGFQGSQCQ----FCS 779
+ C S C ++ NG C C++ G +C F
Sbjct: 214 QHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKDTATGVRCSCPVGFTL 273
Query: 780 DPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI 839
P+ + +CL +G C++ + CR G L D++T + C
Sbjct: 274 QPDGKTCKDINECLVNNGGCDHFCRNTVGSFECGCRKGYK-LLTDERTCQD---IDECSF 329
Query: 840 HATCEY----SNGTASCICKAGYEGDGTL-CSEMDPCTGLTPGGCSRNAECIKTGTGTHT 894
TC++ S G+ C+C GY GT C ++D C+ ++ G C + C+ T G++
Sbjct: 330 ERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECS-MSNGSCDQG--CVNT-KGSYE 385
Query: 895 CVCQQG----WTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNEC 938
CVC G W NG+DC E CL + SC G G C
Sbjct: 386 CVCPPGRRLHW--NGKDCVETGKCLSRAKTSPRAQLSCSKAG-GVESC 430
Score = 63.5 bits (153), Expect = 2e-09
Identities = 72/262 (27%), Positives = 89/262 (33%), Gaps = 43/262 (16%)
Query: 86 GCRHICRKDYLQPRCCPGRWGPDCIECPGGAGSPCN-GRGSC---AEGMEGNGTCSCQEG 141
GC HICR+ C R G D + CN G G C E + TC C +
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPTCGCHQK 231
Query: 142 F-----GGTACETCADDNLFGPSCSSVC-NCVHGVCNSGLDGDGTCECYSAYT----GPK 191
+ G T ETCA +N C C + GV C C +T G
Sbjct: 232 YALHSDGRTCIETCAVNN---GGCDRTCKDTATGV---------RCSCPVGFTLQPDGKT 279
Query: 192 CDKPIPECAALLCPENSRCSPSTEDE-NKLECKCLPNYR--GDGKYCDPINPC-LRKICH 247
C K I EC N C + EC C Y+ D + C I+ C + C
Sbjct: 280 C-KDINECLV----NNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCD 334
Query: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQV-CLPVDPCQINFGNCPTKSTVCKYDGPGQSHCE 306
H P C C GY G C VD C ++ G+C K G C
Sbjct: 335 ---HICINSPGSFQCLCHRGYILYGTTHCGDVDECSMSNGSCDQGCVNTK----GSYECV 387
Query: 307 CKEHYQNFVPGVGCSMTDICKS 328
C + G C T C S
Sbjct: 388 CPPGRRLHWNGKDCVETGKCLS 409
Score = 57.4 bits (137), Expect = 2e-07
Identities = 46/170 (27%), Positives = 63/170 (37%), Gaps = 38/170 (22%)
Query: 210 CSPSTED----------ENKLECKCLPNYRGDGKYCDPINPCLRKICHPH-AHCTYLGPN 258
CS T+D +C C P Y+G+GK C+ I+ C + H P
Sbjct: 37 CSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHECINIPG 96
Query: 259 RHSCTCQEGY--RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKE------- 309
+ CTC +G+ DG CL VD CQ N G C +C + G C+C
Sbjct: 97 NYRCTCFDGFMLAHDGHNCLDVDECQDNNGGC---QQIC-VNAMGSYECQCHSGFFLSDN 152
Query: 310 -----HYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGY 354
H N G+ C D+ C C G C C+ G+
Sbjct: 153 QHTCIHRSN--EGMNC-----MNKDHGCAH--ICRETPKGGVACDCRPGF 193
Score = 49.7 bits (117), Expect = 4e-05
Identities = 51/193 (26%), Positives = 76/193 (39%), Gaps = 29/193 (15%)
Query: 1369 TGV-CECGEGFS----GTACETCTEGKYGIHCDQACSCVHGRCN---QGPLGDGSCDCDV 1420
TGV C C GF+ G C+ E C +G C+ + +G C C
Sbjct: 261 TGVRCSCPVGFTLQPDGKTCKDINE----------CLVNNGGCDHFCRNTVGSFECGCRK 310
Query: 1421 GWRGVHCDNATTED--NCNGTCHTSANCLTNSDGTASCKCAAGFQGNGTI-CTAINACEI 1477
G++ + D T +D C+ C+ NS G+ C C G+ GT C ++ C +
Sbjct: 311 GYK-LLTDERTCQDIDECSFERTCDHICI-NSPGSFQCLCHRGYILYGTTHCGDVDECSM 368
Query: 1478 SNGGCSAKADCKRTTPGRRVCTCKAG--YTGDGIVCLEINPCLENHGGCDK-NAECTQTG 1534
SNG C T G C C G +G C+E CL + C++ G
Sbjct: 369 SNGSCDQGC---VNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAG 425
Query: 1535 PNQAACNCLPAYT 1547
++ PA+T
Sbjct: 426 GVESCFLSCPAHT 438
Score = 43.1 bits (100), Expect = 0.003
Identities = 66/260 (25%), Positives = 88/260 (33%), Gaps = 57/260 (21%)
Query: 1936 GCRERCSLVIQIPRC-CKGYF-----GRDC-QACP---GGPDAPCNNRGVCLDQYSATG- 1984
GC+ C P C C + GR C + C GG D C + +ATG
Sbjct: 212 GCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETCAVNNGGCDRTCKD--------TATGV 263
Query: 1985 ECKCNTGF----NGTACEMCWPGRFGPDCLPCGCSDHGQCDD---GITGSGQCLCETGWT 2037
C C GF +G C+ +CL ++G CD GS +C C G+
Sbjct: 264 RCSCPVGFTLQPDGKTCKDI------NECLV----NNGGCDHFCRNTVGSFECGCRKGYK 313
Query: 2038 GPSCDTQAVLPAVCTPPCSAHATCKE-------NNTCECNLDYEGDGIT-CTVVDFCKQD 2089
+ + CS TC + C C+ Y G T C VD C
Sbjct: 314 LLTDERTCQ----DIDECSFERTCDHICINSPGSFQCLCHRGYILYGTTHCGDVDECSMS 369
Query: 2090 NGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADGLNGGCHEHATCKMTGPG 2147
NG C + C C C G + +G C E C +C G G
Sbjct: 370 NGSCDQ--GCVNTKGSYECVCPPGRRLHWNGKDCVETGKCLSRAKTSPRAQLSCSKAG-G 426
Query: 2148 KHKC--ECKSH--YVGDGLN 2163
C C +H +V D N
Sbjct: 427 VESCFLSCPAHTLFVPDSEN 446
Score = 38.1 bits (87), Expect = 0.11
Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEGDGFLC 993
+ C E T CH A CQ+T + C+C+ GY+G+G C
Sbjct: 34 VDECSEGTDDCHIDAICQNTPKS-YKCLCKPGYKGEGKQC 72
Score = 35.8 bits (81), Expect = 0.56
Identities = 46/208 (22%), Positives = 67/208 (32%), Gaps = 59/208 (28%)
Query: 43 CRSCALNLGVKCPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHICRKDYLQPRCCP 102
C+ A + CP G+T+ G + C+ ++ ++ GC H CR
Sbjct: 256 CKDTATGVRCSCPVGFTLQPDG----KTCK---DINECLVNNGGCDHFCRNTV------- 301
Query: 103 GRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACE-TCADDNLFGPSCS 161
G+ C C++G+ E TC D + CS
Sbjct: 302 -----------------------------GSFECGCRKGYKLLTDERTCQDID----ECS 328
Query: 162 SVCNCVHGVCNSGLDGDGTCECYSAYT--GPKCDKPIPECAALLCPENSRCSPS-TEDEN 218
C H NS G C C+ Y G + EC+ N C +
Sbjct: 329 FERTCDHICINS--PGSFQCLCHRGYILYGTTHCGDVDECSM----SNGSCDQGCVNTKG 382
Query: 219 KLECKCLPNYR--GDGKYCDPINPCLRK 244
EC C P R +GK C CL +
Sbjct: 383 SYECVCPPGRRLHWNGKDCVETGKCLSR 410
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 94.7 bits (234), Expect = 1e-18
Identities = 81/281 (28%), Positives = 125/281 (44%), Gaps = 36/281 (12%)
Query: 728 CCKGFYG-----PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS-QCQFCSDP 781
C +GF G D ++C N C+ NG C++ L G+ C C +G+ + + C D
Sbjct: 1026 CTEGFRGWNGQCLDVDECLE--PNVCA-NGDCSN-LEGSYMCSCHKGYTRTPDHKHCRDI 1081
Query: 782 NKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 839
++ C + LCV+G C N + C G SA + + C Q H+
Sbjct: 1082 DE----CQQGNLCVNGQCKNT-EGSFRCTCGQGYQLSAAKDQCEDIDEC----QHRHLCA 1132
Query: 840 HATCEYSNGTASCICKAGY--EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVC 897
H C + G+ C+C GY G G C +++ C L + +CI T G++ C C
Sbjct: 1133 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC--LEDKSVCQRGDCINT-AGSYDCTC 1189
Query: 898 QQGW-TGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPI 954
G+ + + C +IN C P G C CL G C C++GF +G CE I
Sbjct: 1190 PDGFQLDDNKTCQDINECEHP--GLCGPQGECLNT-EGSFHCVCQQGFSISADGRTCEDI 1246
Query: 955 TSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG--DGFLC 993
C+ T C C +T +G + C+C +G++ DG C
Sbjct: 1247 DECVNNT-VCDSHGFCDNT-AGSFRCLCYQGFQAPQDGQGC 1285
Score = 90.9 bits (224), Expect = 1e-17
Identities = 91/345 (26%), Positives = 131/345 (37%), Gaps = 47/345 (13%)
Query: 1272 CDNNDTTIIRGRCRT---CSSELTCPFGTKSLGNEKRRCI-YTSYFMGRRTLFIGCQPKC 1327
CD+ RGRC C + TCP +C+ T F G +
Sbjct: 985 CDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECL 1044
Query: 1328 VRTVITRECCAGFFGPQCQPC-------PGNAQ----NVCFGNGICLDG----VNGTGVC 1372
V C+ G C P + + C +C++G G+ C
Sbjct: 1045 EPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC 1104
Query: 1373 ECGEGFSGTA----CETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWR----G 1424
CG+G+ +A CE E C C HG+C G C CD G+R G
Sbjct: 1105 TCGQGYQLSAAKDQCEDIDE------CQHRHLCAHGQCRNTE-GSFQCVCDQGYRASGLG 1157
Query: 1425 VHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ-GNGTICTAINACEISNGGCS 1483
HC++ C +C+ N+ G+ C C GFQ + C IN CE G C
Sbjct: 1158 DHCEDINECLEDKSVCQRG-DCI-NTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCG 1214
Query: 1484 AKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACN 1541
+ +C T G C C+ G++ DG C +I+ C+ N+ CD + C T C
Sbjct: 1215 PQGECLNTE-GSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTA-GSFRCL 1271
Query: 1542 CLPAYTG--DGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTC 1584
C + DG+ C +N C +G C E A C + + C C
Sbjct: 1272 CYQGFQAPQDGQGCVDVNECELLSGVCGE-AFCENV-EGSFLCVC 1314
Score = 83.2 bits (204), Expect = 3e-15
Identities = 89/343 (25%), Positives = 135/343 (39%), Gaps = 60/343 (17%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPG-CRHICRKDYLQPRCCPGRWGPDCIEC 112
C +G+ + T VG C Y Y ++ G C I + L P CP C+
Sbjct: 968 CGEGHCVNT---VGAFRCEYCDS--GYRMTQRGRCEDI--DECLNPSTCPDE---QCVNS 1017
Query: 113 PGGAGS-PC-------NGR----------GSCAEG----MEGNGTCSCQEGFGGTACET- 149
PG PC NG+ CA G +EG+ CSC +G+ T
Sbjct: 1018 PGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKH 1077
Query: 150 CADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAY----TGPKCDKPIPECAALLCP 205
C D + C CV+G C + +G C C Y +C+ I EC
Sbjct: 1078 CRDID----ECQQGNLCVNGQCKN-TEGSFRCTCGQGYQLSAAKDQCED-IDECQHRHLC 1131
Query: 206 ENSRCSPSTEDENKLECKCLPNYR--GDGKYCDPINPCL--RKICHPHAHCTYLGPNRHS 261
+ +C + E +C C YR G G +C+ IN CL + +C G +
Sbjct: 1132 AHGQCRNT---EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS--YD 1186
Query: 262 CTCQEGYR-GDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC 320
CTC +G++ D + C ++ C+ + G C + +G HC C++ + G C
Sbjct: 1187 CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEG--SFHCVCQQGFSISADGRTC 1243
Query: 321 SMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG--DGLTC 361
D C ++ C + C A G C+C +G+ DG C
Sbjct: 1244 EDIDECVNNTVCDSHGFCDNTA-GSFRCLCYQGFQAPQDGQGC 1285
Score = 66.6 bits (161), Expect = 3e-10
Identities = 75/283 (26%), Positives = 103/283 (36%), Gaps = 63/283 (22%)
Query: 120 CNGRGSCAEGM----EGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH--GVCNS 173
C R CA G EG+ C C +G+ + G C + C+ VC
Sbjct: 1125 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASG---------LGDHCEDINECLEDKSVCQR 1175
Query: 174 G----LDGDGTCECYSAYT--GPKCDKPIPECAAL-LCPENSRCSPSTEDENKLECKCLP 226
G G C C + K + I EC LC C E C C
Sbjct: 1176 GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC---LNTEGSFHCVCQQ 1232
Query: 227 NYR--GDGKYCDPINPCLRK-ICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCLPVDPC 281
+ DG+ C+ I+ C+ +C H C + C C +G++ DGQ C+ V+ C
Sbjct: 1233 GFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGS-FRCLCYQGFQAPQDGQGCVDVNEC 1291
Query: 282 QINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS----------DNP 331
++ G C C+ + G C C + Q + P MT C+S D P
Sbjct: 1292 ELLSGVC--GEAFCE-NVEGSFLCVCADENQEYSP-----MTGQCRSRTSTDLDVDVDQP 1343
Query: 332 ------CHRNAN----CTTV-APGRT--ECICQKGYVGDGLTC 361
C+ N N C V AP T EC C G G G C
Sbjct: 1344 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNC 1385
Score = 62.8 bits (151), Expect = 4e-09
Identities = 81/341 (23%), Positives = 120/341 (35%), Gaps = 28/341 (8%)
Query: 1270 NRCDNNDTTIIRGRCRTCSSELTCP-FGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCV 1328
N C N G C TC + ++R+C+ + + Q +C
Sbjct: 876 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECT--QVQHLCSQGRCE 933
Query: 1329 RTVITRECC--AGFF----GPQCQPCPGNAQNVCFGNGICLDGVNGTGVCE-CGEGFSGT 1381
T + C AGF G C + G G C++ V G CE C G+ T
Sbjct: 934 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV-GAFRCEYCDSGYRMT 992
Query: 1382 ACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCH 1441
C + C +C +C P C G+RG + ++
Sbjct: 993 QRGRCEDID---ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVC 1049
Query: 1442 TSANCLTNSDGTASCKCAAGFQG--NGTICTAINACEISNGGCSAKADCKRTTPGRRVCT 1499
+ +C +N +G+ C C G+ + C I+ C+ G CK T R CT
Sbjct: 1050 ANGDC-SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ--QGNLCVNGQCKNTEGSFR-CT 1105
Query: 1500 CKAGYTGDGIV--CLEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLI 1556
C GY C +I+ C H + +C T G Q C+ +G G C I
Sbjct: 1106 CGQGYQLSAAKDQCEDIDECQHRH--LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 1163
Query: 1557 NVCLTKNGGCSEFAICNHTGQVERTCTCKPNY-IGDGFTCR 1596
N CL C N G + CTC + + D TC+
Sbjct: 1164 NECLEDKSVCQRGDCINTAGSYD--CTCPDGFQLDDNKTCQ 1202
Score = 62.4 bits (150), Expect = 6e-09
Identities = 68/245 (27%), Positives = 100/245 (40%), Gaps = 26/245 (10%)
Query: 750 GNGQCADSLGGNGTCICEEGFQGSQCQF-CSDPNKYGPRCNK-KCLCVHGTCNNRIDSDG 807
G G C + L TCIC EG++ S+ Q C D ++ C + + LC G C N S
Sbjct: 886 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDE----CTQVQHLCSQGRCENTEGSFL 940
Query: 808 ACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASC-ICKAGYE-GDGTLC 865
G C P V C C + G C C +GY C
Sbjct: 941 CICPAGFMASEEGTNCIDVDECLRPDV--CG-EGHCVNTVGAFRCEYCDSGYRMTQRGRC 997
Query: 866 SEMDPCTGLTPGGCSRNAECIKTGTGTHTCV-CQQGWTGNGRDCSEINNCLLPSAGGCHD 924
++D C L P C + +C+ + G++ CV C +G+ G C +++ CL P+
Sbjct: 998 EDIDEC--LNPSTCP-DEQCVNS-PGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA--- 1050
Query: 925 NASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVC 982
N C + G C C KG+ + C I C Q G C++T G + C C
Sbjct: 1051 NGDCSNL-EGSYMCSCHKGYTRTPDHKHCRDIDEC--QQGNLCVNGQCKNT-EGSFRCTC 1106
Query: 983 QEGYE 987
+GY+
Sbjct: 1107 GQGYQ 1111
Score = 58.2 bits (139), Expect = 1e-07
Identities = 58/228 (25%), Positives = 87/228 (38%), Gaps = 29/228 (12%)
Query: 1970 CNNRGVCLDQYSATGE----CKCNTGFNGTAC-EMCWPGRFGPDCLPCGCSDHGQCDDGI 2024
C +C++ E C C G+ +A + C +C HGQC +
Sbjct: 1084 CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQC---EDIDECQHRHLCAHGQCRN-T 1139
Query: 2025 TGSGQCLCETGWT----GPSC-DTQAVLP--AVCTPPCSAHATCKENNTCECNLDYEGDG 2077
GS QC+C+ G+ G C D L +VC + + TC + D
Sbjct: 1140 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DN 1198
Query: 2078 ITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADGLNGGC 2135
TC ++ C+ G C C C CQ+G+ DG +C +ID C + N C
Sbjct: 1199 KTCQDINECEHP-GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN--NTVC 1255
Query: 2136 HEHATCKMTGPGKHKCECKSHYVG--DGLNCEPEQLPIDRCLQDNGQC 2181
H C T G +C C + DG C + ++ C +G C
Sbjct: 1256 DSHGFCDNTA-GSFRCLCYQGFQAPQDGQGC----VDVNECELLSGVC 1298
Score = 52.8 bits (125), Expect = 4e-06
Identities = 60/242 (24%), Positives = 84/242 (34%), Gaps = 26/242 (10%)
Query: 122 GRGSCAEGMEGNGTCSCQEGFGGTACET-CADDNLFGPSCSSVCN-CVHGVCNSGLDGDG 179
G G C + TC C EG+ + + C D + C+ V + C G C + +G
Sbjct: 886 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDID----ECTQVQHLCSQGRCEN-TEGSF 939
Query: 180 TCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECK-CLPNYRGDGK-YCDP 237
C C + + + + L P+ C+ C YR + C+
Sbjct: 940 LCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED 999
Query: 238 INPCLRKICHPHAHCTYLGPNRHSCT-CQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCK 296
I+ CL P C P + C C EG+RG CL VD C + VC
Sbjct: 1000 IDECLNPSTCPDEQCVN-SPGSYQCVPCTEGFRGWNGQCLDVDEC--------LEPNVCA 1050
Query: 297 YDG----PGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQK 352
G C C + Y C D C+ N C N C G C C +
Sbjct: 1051 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC-VNGQCKN-TEGSFRCTCGQ 1108
Query: 353 GY 354
GY
Sbjct: 1109 GY 1110
Score = 40.0 bits (92), Expect = 0.029
Identities = 44/183 (24%), Positives = 63/183 (34%), Gaps = 29/183 (15%)
Query: 2014 CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDY 2073
CS G+C++ GS C+C G+ T + C P N +Y
Sbjct: 927 CSQ-GRCEN-TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY 984
Query: 2074 EGDGITCTVVDFCKQDNGGCAKVARCSQK------GTKVSCSCQKGYKGDGHSCTEIDPC 2127
G T C +D C + C + G+ C +G++G C ++D C
Sbjct: 985 CDSGYRMTQRGRC-EDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC 1043
Query: 2128 ADG---LNGGCHEHATCKMTGPGKHKCECKSHY--VGDGLNCEPEQLPIDRCLQD----N 2178
+ NG C G + C C Y D +C ID C Q N
Sbjct: 1044 LEPNVCANGDCSNL-------EGSYMCSCHKGYTRTPDHKHCR----DIDECQQGNLCVN 1092
Query: 2179 GQC 2181
GQC
Sbjct: 1093 GQC 1095
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 1457 KCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD 1507
+C G++ N T C IN C++ G +C T R CTCK G+ D
Sbjct: 611 ECLPGYKRVNNTFCQDINECQLQ--GVCPNGECLNTMGSYR-CTCKIGFGPD 659
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 94.7 bits (234), Expect = 1e-18
Identities = 81/281 (28%), Positives = 125/281 (44%), Gaps = 36/281 (12%)
Query: 728 CCKGFYG-----PDCNQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGS-QCQFCSDP 781
C +GF G D ++C N C+ NG C++ L G+ C C +G+ + + C D
Sbjct: 700 CTEGFRGWNGQCLDVDECLE--PNVCA-NGDCSN-LEGSYMCSCHKGYTRTPDHKHCRDI 755
Query: 782 NKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHI-- 839
++ C + LCV+G C N + C G SA + + C Q H+
Sbjct: 756 DE----CQQGNLCVNGQCKNT-EGSFRCTCGQGYQLSAAKDQCEDIDEC----QHRHLCA 806
Query: 840 HATCEYSNGTASCICKAGY--EGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVC 897
H C + G+ C+C GY G G C +++ C L + +CI T G++ C C
Sbjct: 807 HGQCRNTEGSFQCVCDQGYRASGLGDHCEDINEC--LEDKSVCQRGDCINT-AGSYDCTC 863
Query: 898 QQGW-TGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGF--RGNGIDCEPI 954
G+ + + C +IN C P G C CL G C C++GF +G CE I
Sbjct: 864 PDGFQLDDNKTCQDINECEHP--GLCGPQGECLNT-EGSFHCVCQQGFSISADGRTCEDI 920
Query: 955 TSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG--DGFLC 993
C+ T C C +T +G + C+C +G++ DG C
Sbjct: 921 DECVNNT-VCDSHGFCDNT-AGSFRCLCYQGFQAPQDGQGC 959
Score = 90.9 bits (224), Expect = 1e-17
Identities = 91/345 (26%), Positives = 131/345 (37%), Gaps = 47/345 (13%)
Query: 1272 CDNNDTTIIRGRCRT---CSSELTCPFGTKSLGNEKRRCI-YTSYFMGRRTLFIGCQPKC 1327
CD+ RGRC C + TCP +C+ T F G +
Sbjct: 659 CDSGYRMTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECL 718
Query: 1328 VRTVITRECCAGFFGPQCQPC-------PGNAQ----NVCFGNGICLDG----VNGTGVC 1372
V C+ G C P + + C +C++G G+ C
Sbjct: 719 EPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC 778
Query: 1373 ECGEGFSGTA----CETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWR----G 1424
CG+G+ +A CE E C C HG+C G C CD G+R G
Sbjct: 779 TCGQGYQLSAAKDQCEDIDE------CQHRHLCAHGQCRNTE-GSFQCVCDQGYRASGLG 831
Query: 1425 VHCDNATTEDNCNGTCHTSANCLTNSDGTASCKCAAGFQ-GNGTICTAINACEISNGGCS 1483
HC++ C +C+ N+ G+ C C GFQ + C IN CE G C
Sbjct: 832 DHCEDINECLEDKSVCQRG-DCI-NTAGSYDCTCPDGFQLDDNKTCQDINECE-HPGLCG 888
Query: 1484 AKADCKRTTPGRRVCTCKAGYT--GDGIVCLEINPCLENHGGCDKNAECTQTGPNQAACN 1541
+ +C T G C C+ G++ DG C +I+ C+ N+ CD + C T C
Sbjct: 889 PQGECLNTE-GSFHCVCQQGFSISADGRTCEDIDECV-NNTVCDSHGFCDNTA-GSFRCL 945
Query: 1542 CLPAYTG--DGKVCTLINVCLTKNGGCSEFAICNHTGQVERTCTC 1584
C + DG+ C +N C +G C E A C + + C C
Sbjct: 946 CYQGFQAPQDGQGCVDVNECELLSGVCGE-AFCENV-EGSFLCVC 988
Score = 83.2 bits (204), Expect = 3e-15
Identities = 89/343 (25%), Positives = 135/343 (39%), Gaps = 60/343 (17%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPG-CRHICRKDYLQPRCCPGRWGPDCIEC 112
C +G+ + T VG C Y Y ++ G C I + L P CP C+
Sbjct: 642 CGEGHCVNT---VGAFRCEYCDS--GYRMTQRGRCEDI--DECLNPSTCPDE---QCVNS 691
Query: 113 PGGAGS-PC-------NGR----------GSCAEG----MEGNGTCSCQEGFGGTACET- 149
PG PC NG+ CA G +EG+ CSC +G+ T
Sbjct: 692 PGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKH 751
Query: 150 CADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAY----TGPKCDKPIPECAALLCP 205
C D + C CV+G C + +G C C Y +C+ I EC
Sbjct: 752 CRDID----ECQQGNLCVNGQCKN-TEGSFRCTCGQGYQLSAAKDQCED-IDECQHRHLC 805
Query: 206 ENSRCSPSTEDENKLECKCLPNYR--GDGKYCDPINPCL--RKICHPHAHCTYLGPNRHS 261
+ +C + E +C C YR G G +C+ IN CL + +C G +
Sbjct: 806 AHGQCRNT---EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGS--YD 860
Query: 262 CTCQEGYR-GDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGC 320
CTC +G++ D + C ++ C+ + G C + +G HC C++ + G C
Sbjct: 861 CTCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEG--SFHCVCQQGFSISADGRTC 917
Query: 321 SMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVG--DGLTC 361
D C ++ C + C A G C+C +G+ DG C
Sbjct: 918 EDIDECVNNTVCDSHGFCDNTA-GSFRCLCYQGFQAPQDGQGC 959
Score = 66.6 bits (161), Expect = 3e-10
Identities = 75/283 (26%), Positives = 103/283 (36%), Gaps = 63/283 (22%)
Query: 120 CNGRGSCAEGM----EGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVH--GVCNS 173
C R CA G EG+ C C +G+ + G C + C+ VC
Sbjct: 799 CQHRHLCAHGQCRNTEGSFQCVCDQGYRASG---------LGDHCEDINECLEDKSVCQR 849
Query: 174 G----LDGDGTCECYSAYT--GPKCDKPIPECAAL-LCPENSRCSPSTEDENKLECKCLP 226
G G C C + K + I EC LC C E C C
Sbjct: 850 GDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGEC---LNTEGSFHCVCQQ 906
Query: 227 NYR--GDGKYCDPINPCLRK-ICHPHAHCTYLGPNRHSCTCQEGYRG--DGQVCLPVDPC 281
+ DG+ C+ I+ C+ +C H C + C C +G++ DGQ C+ V+ C
Sbjct: 907 GFSISADGRTCEDIDECVNNTVCDSHGFCDNTAGS-FRCLCYQGFQAPQDGQGCVDVNEC 965
Query: 282 QINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS----------DNP 331
++ G C C+ + G C C + Q + P MT C+S D P
Sbjct: 966 ELLSGVC--GEAFCE-NVEGSFLCVCADENQEYSP-----MTGQCRSRTSTDLDVDVDQP 1017
Query: 332 ------CHRNAN----CTTV-APGRT--ECICQKGYVGDGLTC 361
C+ N N C V AP T EC C G G G C
Sbjct: 1018 KEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSG-AGWGDNC 1059
Score = 62.8 bits (151), Expect = 4e-09
Identities = 81/341 (23%), Positives = 120/341 (35%), Gaps = 28/341 (8%)
Query: 1270 NRCDNNDTTIIRGRCRTCSSELTCP-FGTKSLGNEKRRCIYTSYFMGRRTLFIGCQPKCV 1328
N C N G C TC + ++R+C+ + + Q +C
Sbjct: 550 NECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECT--QVQHLCSQGRCE 607
Query: 1329 RTVITRECC--AGFF----GPQCQPCPGNAQNVCFGNGICLDGVNGTGVCE-CGEGFSGT 1381
T + C AGF G C + G G C++ V G CE C G+ T
Sbjct: 608 NTEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTV-GAFRCEYCDSGYRMT 666
Query: 1382 ACETCTEGKYGIHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCH 1441
C + C +C +C P C G+RG + ++
Sbjct: 667 QRGRCEDID---ECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVC 723
Query: 1442 TSANCLTNSDGTASCKCAAGFQG--NGTICTAINACEISNGGCSAKADCKRTTPGRRVCT 1499
+ +C +N +G+ C C G+ + C I+ C+ G CK T R CT
Sbjct: 724 ANGDC-SNLEGSYMCSCHKGYTRTPDHKHCRDIDECQ--QGNLCVNGQCKNTEGSFR-CT 779
Query: 1500 CKAGYTGDGIV--CLEINPCLENHGGCDKNAECTQT-GPNQAACNCLPAYTGDGKVCTLI 1556
C GY C +I+ C H + +C T G Q C+ +G G C I
Sbjct: 780 CGQGYQLSAAKDQCEDIDECQHRH--LCAHGQCRNTEGSFQCVCDQGYRASGLGDHCEDI 837
Query: 1557 NVCLTKNGGCSEFAICNHTGQVERTCTCKPNY-IGDGFTCR 1596
N CL C N G + CTC + + D TC+
Sbjct: 838 NECLEDKSVCQRGDCINTAGSYD--CTCPDGFQLDDNKTCQ 876
Score = 62.4 bits (150), Expect = 6e-09
Identities = 68/245 (27%), Positives = 100/245 (40%), Gaps = 26/245 (10%)
Query: 750 GNGQCADSLGGNGTCICEEGFQGSQCQF-CSDPNKYGPRCNK-KCLCVHGTCNNRIDSDG 807
G G C + L TCIC EG++ S+ Q C D ++ C + + LC G C N S
Sbjct: 560 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDIDE----CTQVQHLCSQGRCENTEGSFL 614
Query: 808 ACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASC-ICKAGYE-GDGTLC 865
G C P V C C + G C C +GY C
Sbjct: 615 CICPAGFMASEEGTNCIDVDECLRPDV--CG-EGHCVNTVGAFRCEYCDSGYRMTQRGRC 671
Query: 866 SEMDPCTGLTPGGCSRNAECIKTGTGTHTCV-CQQGWTGNGRDCSEINNCLLPSAGGCHD 924
++D C L P C + +C+ + G++ CV C +G+ G C +++ CL P+
Sbjct: 672 EDIDEC--LNPSTCP-DEQCVNS-PGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA--- 724
Query: 925 NASCLYVGPGQNECECKKGF--RGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVC 982
N C + G C C KG+ + C I C Q G C++T G + C C
Sbjct: 725 NGDCSNL-EGSYMCSCHKGYTRTPDHKHCRDIDEC--QQGNLCVNGQCKNT-EGSFRCTC 780
Query: 983 QEGYE 987
+GY+
Sbjct: 781 GQGYQ 785
Score = 58.2 bits (139), Expect = 1e-07
Identities = 58/228 (25%), Positives = 87/228 (38%), Gaps = 29/228 (12%)
Query: 1970 CNNRGVCLDQYSATGE----CKCNTGFNGTAC-EMCWPGRFGPDCLPCGCSDHGQCDDGI 2024
C +C++ E C C G+ +A + C +C HGQC +
Sbjct: 758 CQQGNLCVNGQCKNTEGSFRCTCGQGYQLSAAKDQC---EDIDECQHRHLCAHGQCRN-T 813
Query: 2025 TGSGQCLCETGWT----GPSC-DTQAVLP--AVCTPPCSAHATCKENNTCECNLDYEGDG 2077
GS QC+C+ G+ G C D L +VC + + TC + D
Sbjct: 814 EGSFQCVCDQGYRASGLGDHCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLD-DN 872
Query: 2078 ITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYK--GDGHSCTEIDPCADGLNGGC 2135
TC ++ C+ G C C C CQ+G+ DG +C +ID C + N C
Sbjct: 873 KTCQDINECEHP-GLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDECVN--NTVC 929
Query: 2136 HEHATCKMTGPGKHKCECKSHYVG--DGLNCEPEQLPIDRCLQDNGQC 2181
H C T G +C C + DG C + ++ C +G C
Sbjct: 930 DSHGFCDNTA-GSFRCLCYQGFQAPQDGQGC----VDVNECELLSGVC 972
Score = 52.8 bits (125), Expect = 4e-06
Identities = 60/242 (24%), Positives = 84/242 (34%), Gaps = 26/242 (10%)
Query: 122 GRGSCAEGMEGNGTCSCQEGFGGTACET-CADDNLFGPSCSSVCN-CVHGVCNSGLDGDG 179
G G C + TC C EG+ + + C D + C+ V + C G C + +G
Sbjct: 560 GAGHCIN-LPVRYTCICYEGYRFSEQQRKCVDID----ECTQVQHLCSQGRCEN-TEGSF 613
Query: 180 TCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLECK-CLPNYRGDGK-YCDP 237
C C + + + + L P+ C+ C YR + C+
Sbjct: 614 LCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCED 673
Query: 238 INPCLRKICHPHAHCTYLGPNRHSCT-CQEGYRGDGQVCLPVDPCQINFGNCPTKSTVCK 296
I+ CL P C P + C C EG+RG CL VD C + VC
Sbjct: 674 IDECLNPSTCPDEQCVN-SPGSYQCVPCTEGFRGWNGQCLDVDEC--------LEPNVCA 724
Query: 297 YDG----PGQSHCECKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQK 352
G C C + Y C D C+ N C N C G C C +
Sbjct: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLC-VNGQCKN-TEGSFRCTCGQ 782
Query: 353 GY 354
GY
Sbjct: 783 GY 784
Score = 40.0 bits (92), Expect = 0.029
Identities = 44/183 (24%), Positives = 63/183 (34%), Gaps = 29/183 (15%)
Query: 2014 CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDY 2073
CS G+C++ GS C+C G+ T + C P N +Y
Sbjct: 601 CSQ-GRCEN-TEGSFLCICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY 658
Query: 2074 EGDGITCTVVDFCKQDNGGCAKVARCSQK------GTKVSCSCQKGYKGDGHSCTEIDPC 2127
G T C +D C + C + G+ C +G++G C ++D C
Sbjct: 659 CDSGYRMTQRGRC-EDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDEC 717
Query: 2128 ADG---LNGGCHEHATCKMTGPGKHKCECKSHY--VGDGLNCEPEQLPIDRCLQD----N 2178
+ NG C G + C C Y D +C ID C Q N
Sbjct: 718 LEPNVCANGDCSNL-------EGSYMCSCHKGYTRTPDHKHCR----DIDECQQGNLCVN 766
Query: 2179 GQC 2181
GQC
Sbjct: 767 GQC 769
Score = 32.7 bits (73), Expect = 4.7
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 1457 KCAAGFQG-NGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGD 1507
+C G++ N T C IN C++ G +C T R CTCK G+ D
Sbjct: 285 ECLPGYKRVNNTFCQDINECQLQ--GVCPNGECLNTMGSYR-CTCKIGFGPD 333
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 94.7 bits (234), Expect = 1e-18
Identities = 84/314 (26%), Positives = 115/314 (36%), Gaps = 69/314 (21%)
Query: 728 CCKGFYGPDCN----QCPGGF--------------------SNPCSGNGQCADSLGGNGT 763
C F G +C+ CPGG S C +G+C GGN +
Sbjct: 524 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 583
Query: 764 CICEEGFQGSQCQFCSD-----PNKYGPRCNK-----KCLCVHGTCNNRIDSD-GACLTG 812
CIC+ GF G+ C D P + G C +C C G D++ CL
Sbjct: 584 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 643
Query: 813 TCR-----------------DGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICK 855
C DG G+ C + C Y C TC S T C C
Sbjct: 644 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT--CSNGGTCYDSGDTFRCACP 701
Query: 856 AGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCL 915
G++G ++ C P C C+ +G + +C+C+ GW GR C+ N
Sbjct: 702 PGWKGSTCAVAKNSSC---LPNPCVNGGTCVGSG-ASFSCICRDGW--EGRTCTHNTNDC 755
Query: 916 LPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHPLASCQSTS 974
P C++ C+ G CEC GF G DC I C Q+ C A+C
Sbjct: 756 NPLP--CYNGGICV-DGVNWFRCECAPGFAGP--DCRINIDEC--QSSPCAYGATCVDEI 808
Query: 975 SGVWSCVCQEGYEG 988
+G + C C G G
Sbjct: 809 NG-YRCSCPPGRAG 821
Score = 88.6 bits (218), Expect = 7e-17
Identities = 76/295 (25%), Positives = 114/295 (38%), Gaps = 64/295 (21%)
Query: 1937 CRERCSLV---IQIP---RCCKGYFGRDCQAC---PG----------------------- 1964
C++ C+L+ +P RC G+ GR C C PG
Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLC 304
Query: 1965 -------GPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDH 2017
G PC N G C++ C C G++G CE + C C++
Sbjct: 305 DKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE-----KAEHACTSNPCANG 359
Query: 2018 GQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN-NTCECNLDYEGD 2076
G C + + +C C +GW+GP+C + + PC+A TC + + EC +
Sbjct: 360 GSCHE-VPSGFECHCPSGWSGPTCALD--IDECASNPCAAGGTCVDQVDGFECICPEQWV 416
Query: 2077 GITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGC 2135
G TC + V+ C+ G C C C C +G+ G H E D CA + C
Sbjct: 417 GATCQLDVNDCR---GQCQHGGTCKDLVNGYQCVCPRGF-GGRHCELERDECA---SSPC 469
Query: 2136 HEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
H C+ G H C C + G CE + +D C + C A+C +L
Sbjct: 470 HSGGLCEDLADGFH-CHCPQGF--SGPLCE---VDVDLC--EPSPCRNGARCYNL 516
Score = 84.7 bits (208), Expect = 1e-15
Identities = 93/378 (24%), Positives = 141/378 (37%), Gaps = 89/378 (23%)
Query: 54 CPDGYTMITSGSVGVRDCR--YTFEVRTYS--LSLPGCRHICRKDYLQP-RC-CPGRWG- 106
C G ++ G +CR Y ++ R + PGC H ++P +C C WG
Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVH---GSCVEPWQCNCETNWGG 301
Query: 107 ----PDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSS 162
D C G+ PC G+C C+C +G+ G CE A+ C++
Sbjct: 302 LLCDKDLNYC--GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK-AEHACTSNPCAN 358
Query: 163 VCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAA-----------------LLCP 205
+C H V SG + C C S ++GP C I ECA+ +CP
Sbjct: 359 GGSC-HEV-PSGFE----CHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICP 412
Query: 206 E---NSRCSPSTED--------------ENKLECKCLPNYRGDGKYCD-PINPCLRKICH 247
E + C D N +C C + G++C+ + C CH
Sbjct: 413 EQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGF--GGRHCELERDECASSPCH 470
Query: 248 PHAHCTYLGPNRHSCTCQEGYRGDGQVC-LPVDPCQINFGNCPTKSTVCKYDGPGQSHCE 306
C L H C C +G+ G +C + VD C+ + P ++ Y+ G +C
Sbjct: 471 SGGLCEDLADGFH-CHCPQGF--SGPLCEVDVDLCEPS----PCRNGARCYNLEGDYYCA 523
Query: 307 CKEHY--------QNFVPGVGCSMTDICKSD-----------NPCHRNANCTTVAPGRTE 347
C + + + PG C + D C SD C + C + G
Sbjct: 524 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 583
Query: 348 CICQKGYVGDGLTCYGNI 365
CIC G+ G C+ NI
Sbjct: 584 CICDSGFT--GTYCHENI 599
Score = 82.4 bits (202), Expect = 5e-15
Identities = 63/215 (29%), Positives = 83/215 (38%), Gaps = 20/215 (9%)
Query: 1951 CKGYFGRDCQACPGGPDAP----CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFG 2006
C+ G A PG P C G C+ Q C C++GF GT C
Sbjct: 545 CRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCH-----ENI 599
Query: 2007 PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKEN- 2064
DCL C + G C D + +C C +GW G CDT P C P PC + C +
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTN---PNDCLPDPCHSRGRCYDLV 655
Query: 2065 NTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEI 2124
N C D G TC +F + D C+ C G C+C G+KG + +
Sbjct: 656 NDFYCACDDGWKGKTCHSREF-QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKN 714
Query: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
C L C TC +G C C+ + G
Sbjct: 715 SSC---LPNPCVNGGTCVGSG-ASFSCICRDGWEG 745
Score = 79.0 bits (193), Expect = 6e-14
Identities = 71/236 (30%), Positives = 88/236 (37%), Gaps = 62/236 (26%)
Query: 1980 YSATGECKC---NTGFNGTACEM-----CWPGRFGPDCLPCGCSD-----HGQCDDGITG 2026
YSAT C N F C+ C G G +C C HG C T
Sbjct: 203 YSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC----TV 258
Query: 2027 SGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENNTCECNLDYEGDGITCTVVDF 2085
G+C C GW G CD C P P H +C E C C ++ G
Sbjct: 259 PGECRCSYGWQGRFCDE-------CVPYPGCVHGSCVEPWQCNCETNWGG--------LL 303
Query: 2086 CKQDNGGCAKVARCSQKGTKVS-------CSCQKGYKGDG-----HSCTEIDPCADGLNG 2133
C +D C C+ GT ++ C+C GY G H+CT +PCA+G G
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPCANG--G 360
Query: 2134 GCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
CHE P +C C S + G C L ID C + C A CVD
Sbjct: 361 SCHE-------VPSGFECHCPSGW--SGPTC---ALDIDECA--SNPCAAGGTCVD 402
Score = 77.0 bits (188), Expect = 2e-13
Identities = 80/297 (26%), Positives = 105/297 (35%), Gaps = 68/297 (22%)
Query: 113 PGGAGSP-CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGV- 170
PG A S C G C GN +C C GF GT C DD L G C + C+ V
Sbjct: 560 PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCL-GQPCRNGGTCIDEVD 618
Query: 171 -----CNSGLDG--------------------------DGTCECYSAYTGPKCDKPIPEC 199
C SG +G D C C + G C +C
Sbjct: 619 AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQC 678
Query: 200 AALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNR 259
A C C S + C C P ++G + CL C C G +
Sbjct: 679 DAYTCSNGGTCYDSGD---TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS- 734
Query: 260 HSCTCQEGYRG-----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNF 314
SC C++G+ G + C P+ PC N G C DG CEC +
Sbjct: 735 FSCICRDGWEGRTCTHNTNDCNPL-PC-YNGGIC--------VDGVNWFRCECAPGF--- 781
Query: 315 VPGVGCSMT-DICKSDNPCHRNANCT--------TVAPGRTECICQKGYVGDGLTCY 362
G C + D C+S +PC A C + PGR CQ+ +G G +C+
Sbjct: 782 -AGPDCRINIDECQS-SPCAYGATCVDEINGYRCSCPPGRAGPRCQE-VIGFGRSCW 835
Score = 76.6 bits (187), Expect = 3e-13
Identities = 85/335 (25%), Positives = 115/335 (34%), Gaps = 76/335 (22%)
Query: 717 RYCNATVKIPKC------------CKGFYG-----PDCNQCPGGFSNPCSGNGQCADSLG 759
R+C+ V P C C+ +G D N C G +PC+ G C ++
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC--GSHHPCTNGGTCINAEP 328
Query: 760 GNGTCICEEGFQGSQCQ-----FCSDPNKYGPRCNK-----KCLCVHG----TCNNRID- 804
C C +G+ G C+ S+P G C++ +C C G TC ID
Sbjct: 329 DQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDE 388
Query: 805 --SDGACLTGTCRDGSAGRLCDKQTSACGPYVQF--------CHIHATCEYSNGTASCIC 854
S+ GTC D G C G Q C TC+ C+C
Sbjct: 389 CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVC 448
Query: 855 KAGYEGDGTLCS-EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINN 913
G+ G C E D C C C G H C C QG++G + +++
Sbjct: 449 PRGF--GGRHCELERDECAS---SPCHSGGLCEDLADGFH-CHCPQGFSGPLCEV-DVDL 501
Query: 914 CLLPSAGGCHDNASCLYVGPGQNECECKKGFRGN----------GIDCEPITSC------ 957
C C + A C Y G C C F G G C I C
Sbjct: 502 C---EPSPCRNGARC-YNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGP 557
Query: 958 ----LEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
+G C P C S G +SC+C G+ G
Sbjct: 558 GMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTG 592
Score = 75.5 bits (184), Expect = 6e-13
Identities = 78/303 (25%), Positives = 112/303 (36%), Gaps = 62/303 (20%)
Query: 715 CARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQG 772
C +Y N C G+ G +C + C G + +G C G C C G+QG
Sbjct: 223 CDQYGNKA-----CMDGWMGKECKEAVCKQGCNLL---HGGCTVP----GECRCSYGWQG 270
Query: 773 SQCQFC------------------SDPNKYGPRCNKK---CLCVH-----GTCNNRIDSD 806
C C + N G C+K C H GTC N
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 807 GACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCS 866
C TC DG +GR C+K AC C +C C C +G+ G T
Sbjct: 331 YRC---TCPDGYSGRNCEKAEHACTS--NPCANGGSCHEVPSGFECHCPSGWSGP-TCAL 384
Query: 867 EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCHDN 925
++D C C+ C+ G C+C + W G C ++N+C G C
Sbjct: 385 DIDECAS---NPCAAGGTCVDQVDG-FECICPEQWV--GATCQLDVNDC----RGQCQHG 434
Query: 926 ASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEG 985
+C + G +C C +GF G + E C + CH C+ + G + C C +G
Sbjct: 435 GTCKDLVNGY-QCVCPRGFGGRHCELER-DEC--ASSPCHSGGLCEDLADG-FHCHCPQG 489
Query: 986 YEG 988
+ G
Sbjct: 490 FSG 492
Score = 73.9 bits (180), Expect = 2e-12
Identities = 63/235 (26%), Positives = 87/235 (37%), Gaps = 56/235 (23%)
Query: 134 GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD 193
G +C +G+ G C+ C CN +HG C G C C + G CD
Sbjct: 227 GNKACMDGWMGKECKEAV--------CKQGCNLLHGGCTV----PGECRCSYGWQGRFCD 274
Query: 194 K--PIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG-----DGKYCDPINPCLRKIC 246
+ P P C C E +C C N+ G D YC +PC
Sbjct: 275 ECVPYPGCVHGSCVE------------PWQCNCETNWGGLLCDKDLNYCGSHHPCTN--- 319
Query: 247 HPHAHCTYLGPNRHSCTCQEGYRG----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQ 302
C P+++ CTC +GY G + +PC N G+C ++ P
Sbjct: 320 --GGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPC-ANGGSC--------HEVPSG 368
Query: 303 SHCECKEHYQNFVPGVGCSM-TDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
C C + G C++ D C S NPC C G ECIC + +VG
Sbjct: 369 FECHCPSGWS----GPTCALDIDECAS-NPCAAGGTCVDQVDG-FECICPEQWVG 417
Score = 69.3 bits (168), Expect = 5e-11
Identities = 74/320 (23%), Positives = 102/320 (31%), Gaps = 87/320 (27%)
Query: 1336 CCAGFFGPQC----QPCPGNA--------------------QNVCFGNGICLDGVNGTGV 1371
C F G C +PCPG A VC +G C+ G
Sbjct: 524 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 583
Query: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSCV----------------------------- 1402
C C GF+GT C + G C +C+
Sbjct: 584 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 643
Query: 1403 ----HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNG-TCHTSANCLTNSDGTASCK 1457
GRC + D C CD GW+G C + E C+ TC C + D T C
Sbjct: 644 PCHSRGRC-YDLVNDFYCACDDGWKGKTCH--SREFQCDAYTCSNGGTCYDSGD-TFRCA 699
Query: 1458 CAAGFQGNGTICTAINAC---EISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
C G++G+ ++C NGG + + C C+ G+ G
Sbjct: 700 CPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS------CICRDGWEG-------- 745
Query: 1515 NPCLENHGGCDK----NAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1570
C N C+ N G N C C P + G IN+ ++ C+ A
Sbjct: 746 RTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPD---CRINIDECQSSPCAYGA 802
Query: 1571 ICNHTGQVERTCTCKPNYIG 1590
C R C+C P G
Sbjct: 803 TCVDEINGYR-CSCPPGRAG 821
Score = 67.8 bits (164), Expect = 1e-10
Identities = 74/296 (25%), Positives = 98/296 (33%), Gaps = 54/296 (18%)
Query: 79 TYSLSLPGCRHICR-----KDYL---QPRCCPGRWGPDC-IECPGGAGSPCNGRGSCAEG 129
T L + CR C+ KD + Q C G G C +E A SPC+ G C +
Sbjct: 419 TCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 478
Query: 130 MEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTG 189
+G C C +GF G CE D +L PS C +G L+GD C C + G
Sbjct: 479 ADGFH-CHCPQGFSGPLCEV--DVDLCEPS-----PCRNGARCYNLEGDYYCACPDDFGG 530
Query: 190 PKCDKPIPECAALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPH 249
C P C C C +P G +C PH
Sbjct: 531 KNCSVPREPCPGGACRVIDGCGSDAGPG-------MPGTAASG------------VCGPH 571
Query: 250 AHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNC---PTKSTVCKYDGPGQSHCE 306
C SC C G+ G C N +C P ++ D C
Sbjct: 572 GRCVSQPGGNFSCICDSGFTG--------TYCHENIDDCLGQPCRNGGTCIDEVDAFRCF 623
Query: 307 CKEHYQNFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCY 362
C ++ G C +PCH C + C C G+ G TC+
Sbjct: 624 CPSGWE----GELCDTNPNDCLPDPCHSRGRCYDLV-NDFYCACDDGW--KGKTCH 672
Score = 67.0 bits (162), Expect = 2e-10
Identities = 82/312 (26%), Positives = 107/312 (34%), Gaps = 85/312 (27%)
Query: 1950 CCKGYFGRDCQACPGGPDA-PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G+ C + DA C+N G C D T C C G+ G+ C +
Sbjct: 662 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDS-GDTFRCACPPGWKGSTCAVAK----NSS 716
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENNT- 2066
CLP C + G C G S C+C GW G +C C P PC C +
Sbjct: 717 CLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNT---NDCNPLPCYNGGICVDGVNW 772
Query: 2067 --CECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG------- 2116
CEC + G C + +D C+ + CA A C + CSC G G
Sbjct: 773 FRCECAPGFAGP--DCRINIDECQ--SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828
Query: 2117 ---------------------DGHSCTEID-------------PC-----ADGLNGGCHE 2137
D +SC +D PC + L+ C
Sbjct: 829 GFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPL 888
Query: 2138 HATCKMTGPG---KHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC--VDLHF 2192
C PG + CE C E+ P CL +G H D C + LHF
Sbjct: 889 GQRCLEKAPGQCLRPPCEAWG-------ECGAEEPPSTPCLPRSG--HLDNNCARLTLHF 939
Query: 2193 ------QDTTVG 2198
Q TTVG
Sbjct: 940 NRDHVPQGTTVG 951
Score = 66.6 bits (161), Expect = 3e-10
Identities = 58/241 (24%), Positives = 85/241 (35%), Gaps = 34/241 (14%)
Query: 1334 RECCAGFFGPQCQPCPGNAQNVCF-GNGICLDGVNGTGVCECGEGFSGTACETCTEGKYG 1392
+ C G+ G +C+ + VC G + G G C C G+ G C+ C
Sbjct: 229 KACMDGWMGKECK------EAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYP-- 280
Query: 1393 IHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG 1452
CVHG C + C+C+ W G+ CD + C C+
Sbjct: 281 -------GCVHGSCVE----PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
C C G+ G A +AC ++ C+ C G C C +G++G L
Sbjct: 330 QYRCTCPDGYSGRNCE-KAEHAC--TSNPCANGGSCHEVPSGFE-CHCPSGWSGP-TCAL 384
Query: 1513 EINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTL-INVCLTKNGGCSEFAI 1571
+I+ C N C C + C C + G C L +N C G C
Sbjct: 385 DIDECASN--PCAAGGTCVDQ-VDGFECICPEQWV--GATCQLDVNDC---RGQCQHGGT 436
Query: 1572 C 1572
C
Sbjct: 437 C 437
Score = 65.1 bits (157), Expect = 9e-10
Identities = 78/321 (24%), Positives = 105/321 (32%), Gaps = 84/321 (26%)
Query: 1336 CCAGFFGPQCQ----PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACET------ 1385
C GF G C+ C A + C G+C D +G C C +GFSG CE
Sbjct: 448 CPRGFGGRHCELERDEC---ASSPCHSGGLCEDLADGFH-CHCPQGFSGPLCEVDVDLCE 503
Query: 1386 ---CTEGK--YGIHCDQACSC--------------------------------------- 1401
C G Y + D C+C
Sbjct: 504 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 563
Query: 1402 ------VHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNG-TCHTSANCLTNSDGTA 1454
HGRC P G+ SC CD G+ G +C D+C G C C+ D
Sbjct: 564 ASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHE--NIDDCLGQPCRNGGTCIDEVD-AF 620
Query: 1455 SCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
C C +G++G +C N + C ++ C C C G+ G E
Sbjct: 621 RCFCPSGWEGE--LCDT-NPNDCLPDPCHSRGRCYDLV-NDFYCACDDGWKGKTCHSREF 676
Query: 1515 NPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTK---NGGC----- 1566
C + C C +G + C C P + G + CL NGG
Sbjct: 677 Q-C--DAYTCSNGGTCYDSG-DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG 732
Query: 1567 SEFAICNHTGQVERTCTCKPN 1587
+ F+ G RTCT N
Sbjct: 733 ASFSCICRDGWEGRTCTHNTN 753
Score = 64.7 bits (156), Expect = 1e-09
Identities = 88/334 (26%), Positives = 108/334 (32%), Gaps = 89/334 (26%)
Query: 1327 CVRTVITRECCAG--FFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACE 1384
CV V EC + G CQ + + C G C D VNG C C GF G CE
Sbjct: 400 CVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGY-QCVCPRGFGGRHCE 458
Query: 1385 TCTEGKYGIHCDQACSCVHGRCNQG----PLGDG-SCDCDVGWRGVHCDNATTEDNCN-G 1438
+ C C+ G L DG C C G+ G C+ D C
Sbjct: 459 L-----------ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE--VDVDLCEPS 505
Query: 1439 TCHTSANCLTNSDGTASCKCAAGFQGN----------GTICTAINAC----------EIS 1478
C A C N +G C C F G G C I+ C +
Sbjct: 506 PCRNGARCY-NLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA 564
Query: 1479 NGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLE-INPCL----ENHGGC--------- 1524
+G C C G C C +G+T G C E I+ CL N G C
Sbjct: 565 SGVCGPHGRCVSQPGGNFSCICDSGFT--GTYCHENIDDCLGQPCRNGGTCIDEVDAFRC 622
Query: 1525 ----DKNAECTQTGPNQAACNCLP-AYTGDGKVCTLIN--VCLTKNG------------- 1564
E T PN +CLP G+ L+N C +G
Sbjct: 623 FCPSGWEGELCDTNPN----DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQC 678
Query: 1565 ---GCSEFAICNHTGQVERTCTCKPNYIGDGFTC 1595
CS C +G R C C P + G TC
Sbjct: 679 DAYTCSNGGTCYDSGDTFR-CACPPGW--KGSTC 709
Score = 62.8 bits (151), Expect = 4e-09
Identities = 83/356 (23%), Positives = 127/356 (35%), Gaps = 51/356 (14%)
Query: 94 DYLQPRCCPGRWGPDCIECPGGA--GSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCA 151
D + C PG G C + +PC G+C G + +C C++G+ G C
Sbjct: 694 DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNT 752
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS 211
+D C+ + G+C G++ CEC + GP C I EC + C + C
Sbjct: 753 ND------CNPLPCYNGGICVDGVNWF-RCECAPGFAGPDCRINIDECQSSPCAYGATC- 804
Query: 212 PSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICH---PHAHCTYLGPNRHSCTCQEGY 268
++ N C C P G C + R P H + + +SC C +G
Sbjct: 805 --VDEINGYRCSCPPGRAGPR--CQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGR 860
Query: 269 RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS 328
R +V PC + G S C P C K Q P
Sbjct: 861 RDCSKVWCGWKPCLLA-GQPEALSAQC----PLGQRCLEKAPGQCLRP------------ 903
Query: 329 DNPCHRNANCTTVAPGRTECICQKGYVGDG---LTCYGNIMERLRELNTEPRGKWQGRLT 385
PC C P T C+ + G++ + LT + N + P+G G +
Sbjct: 904 --PCEAWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFN-------RDHVPQGTTVGAIC 954
Query: 386 SFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAG 441
S I L A +L ++L D+ G + E+ V A+ +I G
Sbjct: 955 SGIRSLPATRAVARDRL----LVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQG 1006
Score = 60.5 bits (145), Expect = 2e-08
Identities = 56/215 (26%), Positives = 75/215 (34%), Gaps = 40/215 (18%)
Query: 780 DPNKYGPRCNKKC-----LCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
D N Y CNK C H TC+ + C DG G+ C + G
Sbjct: 199 DENYYSATCNKFCRPRNDFFGHYTCDQYGNK-------ACMDGWMGKECKEAVCKQG--- 248
Query: 835 QFCHI-HATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTH 893
C++ H C T C+ Y G C E P G G C +
Sbjct: 249 --CNLLHGGC-----TVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQ--------- 292
Query: 894 TCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP 953
C C+ W G D ++N C S C + +C+ P Q C C G+ G +CE
Sbjct: 293 -CNCETNWGGLLCD-KDLNYC--GSHHPCTNGGTCINAEPDQYRCTCPDGYSGR--NCEK 346
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
+ C SC SG + C C G+ G
Sbjct: 347 AEHAC-TSNPCANGGSCHEVPSG-FECHCPSGWSG 379
Score = 55.5 bits (132), Expect = 7e-07
Identities = 64/273 (23%), Positives = 92/273 (33%), Gaps = 77/273 (28%)
Query: 1950 CCKGYFGRDCQA----CPGGPDAPCNNRGVCLDQYSATGECKCNTGFNGTACE----MCW 2001
C +G+ GR C+ C +PC++ G+C D C C GF+G CE +C
Sbjct: 448 CPRGFGGRHCELERDECAS---SPCHSGGLCEDLADGF-HCHCPQGFSGPLCEVDVDLCE 503
Query: 2002 PG--RFGPDCL------------------------PCG---------------------- 2013
P R G C PC
Sbjct: 504 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 563
Query: 2014 ----CSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN---NT 2066
C HG+C G+ C+C++G+TG C + PC TC +
Sbjct: 564 ASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN--IDDCLGQPCRNGGTCIDEVDAFR 621
Query: 2067 CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDP 2126
C C +EG+ + T + C D C RC C+C G+K G +C +
Sbjct: 622 CFCPSGWEGE-LCDTNPNDCLPD--PCHSRGRCYDLVNDFYCACDDGWK--GKTCHSREF 676
Query: 2127 CADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
D C TC +G +C C + G
Sbjct: 677 QCDAYT--CSNGGTCYDSG-DTFRCACPPGWKG 706
Score = 54.3 bits (129), Expect = 2e-06
Identities = 63/224 (28%), Positives = 84/224 (37%), Gaps = 32/224 (14%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI-CRK--------DYLQPRCCPGR 104
C +G T + SG+ CR +E RT + + C + C ++ + C PG
Sbjct: 722 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 781
Query: 105 WGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSC-SS 162
GPDC I SPC +C + + G CSC G G C+ FG SC S
Sbjct: 782 AGPDCRINIDECQSSPCAYGATCVDEINGY-RCSCPPGRAGPRCQEVIG---FGRSCWSR 837
Query: 163 VCNCVHGV-----CNSGLDGDGTCECYSAYTG--PKCDKPIPECAALLCPENSRCSPSTE 215
HG CNS DG +C + G P PE + CP RC
Sbjct: 838 GTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCL---- 893
Query: 216 DENKLECKCL----PNYRGDGKYCDPINPCLRKICHPHAHCTYL 255
K +CL + G P PCL + H +C L
Sbjct: 894 --EKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCARL 935
Score = 50.4 bits (119), Expect = 2e-05
Identities = 62/248 (25%), Positives = 86/248 (34%), Gaps = 52/248 (20%)
Query: 1386 CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCD------CDVGWRGVHCDNATTEDNCN-- 1437
C E Y C++ C R G +CD C GW G C A + CN
Sbjct: 198 CDENYYSATCNKFC-----RPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLL 252
Query: 1438 -GTCHTSANCLTN-------------SDGTASCKCAAGFQGN------GTICTA-INACE 1476
G C C + G C +Q N G +C +N C
Sbjct: 253 HGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCG 312
Query: 1477 ISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEINPCLENHGGCDKNAECTQTGPN 1536
S+ C+ C P + CTC GY+G E + C N C C + P+
Sbjct: 313 -SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAE-HACTSN--PCANGGSCHEV-PS 367
Query: 1537 QAACNCLPAYTGDGKVCTL-INVCLTKNGGCSEFAICNHTGQVER-TCTCKPNYIG---- 1590
C+C ++ G C L I+ C + C+ C QV+ C C ++G
Sbjct: 368 GFECHCPSGWS--GPTCALDIDEC--ASNPCAAGGTC--VDQVDGFECICPEQWVGATCQ 421
Query: 1591 -DGFTCRG 1597
D CRG
Sbjct: 422 LDVNDCRG 429
Score = 48.9 bits (115), Expect = 6e-05
Identities = 45/193 (23%), Positives = 63/193 (32%), Gaps = 26/193 (13%)
Query: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHG 1404
C P P C+ GIC+DGVN CEC GF+G C + I Q+ C +G
Sbjct: 755 CNPLP------CYNGGICVDGVNWFR-CECAPGFAGPDC------RINIDECQSSPCAYG 801
Query: 1405 RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNS----DGTASCKCAA 1460
+ C C G G C +C + + + SC+C
Sbjct: 802 ATCVDEINGYRCSCPPGRAGPRCQEVI---GFGRSCWSRGTPFPHGSSWVEDCNSCRCLD 858
Query: 1461 GFQGNGTI------CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
G + + C E + C C PG+ + + G
Sbjct: 859 GRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPPS 918
Query: 1515 NPCLENHGGCDKN 1527
PCL G D N
Sbjct: 919 TPCLPRSGHLDNN 931
Score = 44.3 bits (103), Expect = 0.002
Identities = 54/241 (22%), Positives = 78/241 (32%), Gaps = 40/241 (16%)
Query: 1335 ECCAGFFGPQCQPCPGNAQ-NVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
EC GF GP C+ Q + C C+D +NG C C G +G C+ +G
Sbjct: 776 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR-CSCPPGRAGPRCQEVI--GFGR 832
Query: 1394 HC-DQACSCVHGR-----CNQGPLGDGSCDCDVGWRG-VHCDNATTEDNCNGTCHTSANC 1446
C + HG CN DG DC W G C A + + C C
Sbjct: 833 SCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRC 892
Query: 1447 LTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTG 1506
L + G + C A +C P C ++G+
Sbjct: 893 LEKAPG-----------------------QCLRPPCEAWGECGAEEPPSTPCLPRSGHLD 929
Query: 1507 DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGC 1566
+ L + H D + T G + LPA + L+ +C + G
Sbjct: 930 NNCARLTL------HFNRDHVPQGTTVGAICSGIRSLPATRAVARDRLLVLLCDRASSGA 983
Query: 1567 S 1567
S
Sbjct: 984 S 984
Score = 39.7 bits (91), Expect = 0.038
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 8/54 (14%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ 776
+C GF GPDC ++C S+PC+ C D + G C C G G +CQ
Sbjct: 776 ECAPGFAGPDCRINIDECQ---SSPCAYGATCVDEINGY-RCSCPPGRAGPRCQ 825
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 94.7 bits (234), Expect = 1e-18
Identities = 84/314 (26%), Positives = 115/314 (36%), Gaps = 69/314 (21%)
Query: 728 CCKGFYGPDCN----QCPGGF--------------------SNPCSGNGQCADSLGGNGT 763
C F G +C+ CPGG S C +G+C GGN +
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 764 CICEEGFQGSQCQFCSD-----PNKYGPRCNK-----KCLCVHGTCNNRIDSD-GACLTG 812
CIC+ GF G+ C D P + G C +C C G D++ CL
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 813 TCR-----------------DGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICK 855
C DG G+ C + C Y C TC S T C C
Sbjct: 682 PCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYT--CSNGGTCYDSGDTFRCACP 739
Query: 856 AGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCSEINNCL 915
G++G ++ C P C C+ +G + +C+C+ GW GR C+ N
Sbjct: 740 PGWKGSTCAVAKNSSC---LPNPCVNGGTCVGSG-ASFSCICRDGW--EGRTCTHNTNDC 793
Query: 916 LPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHPLASCQSTS 974
P C++ C+ G CEC GF G DC I C Q+ C A+C
Sbjct: 794 NPLP--CYNGGICV-DGVNWFRCECAPGFAGP--DCRINIDEC--QSSPCAYGATCVDEI 846
Query: 975 SGVWSCVCQEGYEG 988
+G + C C G G
Sbjct: 847 NG-YRCSCPPGRAG 859
Score = 84.7 bits (208), Expect = 1e-15
Identities = 78/311 (25%), Positives = 117/311 (37%), Gaps = 68/311 (21%)
Query: 1937 CRERCSLV---IQIP---RCCKGYFGRDCQAC---PG----------------------- 1964
C++ C+L+ +P RC G+ GR C C PG
Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLC 304
Query: 1965 -------GPDAPCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPDCLPCGCSDH 2017
G PC N G C++ C C G++G CE + C C++
Sbjct: 305 DKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE-----KAEHACTSNPCANG 359
Query: 2018 GQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKEN-NTCECNLDYEGD 2076
G C + + +C C +GW+GP+C + + PC+A TC + + EC +
Sbjct: 360 GSCHE-VPSGFECHCPSGWSGPTCALD--IDECASNPCAAGGTCVDQVDGFECICPEQWV 416
Query: 2077 GITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCH 2136
G TC +D + + C C C C G+KG + ++ C G C
Sbjct: 417 GATCQ-LDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGI-NCHINVNDC----RGQCQ 470
Query: 2137 EHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDLHFQDTT 2196
TCK G ++C C + G +CE E+ D C + CH+ C DL
Sbjct: 471 HGGTCKDLVNG-YQCVCPRGF--GGRHCELER---DECA--SSPCHSGGLCEDL------ 516
Query: 2197 VGVFHLRSPLG 2207
FH P G
Sbjct: 517 ADGFHCHCPQG 527
Score = 82.4 bits (202), Expect = 5e-15
Identities = 63/215 (29%), Positives = 83/215 (38%), Gaps = 20/215 (9%)
Query: 1951 CKGYFGRDCQACPGGPDAP----CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFG 2006
C+ G A PG P C G C+ Q C C++GF GT C
Sbjct: 583 CRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCH-----ENI 637
Query: 2007 PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKEN- 2064
DCL C + G C D + +C C +GW G CDT P C P PC + C +
Sbjct: 638 DDCLGQPCRNGGTCIDEVDAF-RCFCPSGWEGELCDTN---PNDCLPDPCHSRGRCYDLV 693
Query: 2065 NTCECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHSCTEI 2124
N C D G TC +F + D C+ C G C+C G+KG + +
Sbjct: 694 NDFYCACDDGWKGKTCHSREF-QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKN 752
Query: 2125 DPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVG 2159
C L C TC +G C C+ + G
Sbjct: 753 SSC---LPNPCVNGGTCVGSG-ASFSCICRDGWEG 783
Score = 80.5 bits (197), Expect = 2e-14
Identities = 89/322 (27%), Positives = 127/322 (39%), Gaps = 55/322 (17%)
Query: 54 CPDGYTMITSGSVGVRDCR--YTFEVRTYS--LSLPGCRHICRKDYLQP-RC-CPGRWG- 106
C G ++ G +CR Y ++ R + PGC H ++P +C C WG
Sbjct: 245 CKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVH---GSCVEPWQCNCETNWGG 301
Query: 107 ----PDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSS 162
D C G+ PC G+C C+C +G+ G CE A+ C++
Sbjct: 302 LLCDKDLNYC--GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK-AEHACTSNPCAN 358
Query: 163 VCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENKLEC 222
+C H V SG + C C S ++GP C I ECA+ C C + + EC
Sbjct: 359 GGSC-HEV-PSGFE----CHCPSGWSGPTCALDIDECASNPCAAGGTC---VDQVDGFEC 409
Query: 223 KCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDGQVCLPVDPCQ 282
C + G D N C K C C L + C C G++G C
Sbjct: 410 ICPEQWVGATCQLD-ANECEGKPCLNAFSCKNL-IGGYYCDCIPGWKGIN--------CH 459
Query: 283 INFGNCPTKSTVCKYDGPGQSHCECKE---HYQNFVP----GVGCSM-TDICKSDNPCHR 334
IN +C + C++ G CK+ YQ P G C + D C S +PCH
Sbjct: 460 INVNDCRGQ---CQHGG------TCKDLVNGYQCVCPRGFGGRHCELERDECAS-SPCHS 509
Query: 335 NANCTTVAPGRTECICQKGYVG 356
C +A G C C +G+ G
Sbjct: 510 GGLCEDLADG-FHCHCPQGFSG 530
Score = 79.3 bits (194), Expect = 4e-14
Identities = 86/319 (26%), Positives = 114/319 (35%), Gaps = 79/319 (24%)
Query: 728 CCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQFCSD--- 780
C +GF G C ++C S+PC G C D L C C +GF G C+ D
Sbjct: 486 CPRGFGGRHCELERDECA---SSPCHSGGLCED-LADGFHCHCPQGFSGPLCEVDVDLCE 541
Query: 781 --PNKYGPRC-----NKKCLCV--HGTCNNRIDSD----GAC--LTGTCRDGSAGRLCDK 825
P + G RC + C C G N + + GAC + G D G
Sbjct: 542 PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTA 601
Query: 826 QTSACGPYVQFCHIHATC-EYSNGTASCICKAGYEGDGTLCSE-MDPCTGLTPGGCSRNA 883
+ CGP H C G SCIC +G+ GT C E +D C G C
Sbjct: 602 ASGVCGP-------HGRCVSQPGGNFSCICDSGF--TGTYCHENIDDCLGQP---CRNGG 649
Query: 884 ECIKTGTGTHTCVCQQGWTGNGRDCSEINNCL---LPSAGGCHD---------------- 924
CI C C GW G D + N+CL S G C+D
Sbjct: 650 TCIDE-VDAFRCFCPSGWEGELCDTNP-NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGK 707
Query: 925 ---------------NASCLYVGPGQNECECKKGFRGNGIDCEPITSCLEQTGKCHPLAS 969
N Y C C G++G+ +SCL C +
Sbjct: 708 TCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL--PNPCVNGGT 765
Query: 970 CQSTSSGVWSCVCQEGYEG 988
C S +SC+C++G+EG
Sbjct: 766 CVG-SGASFSCICRDGWEG 783
Score = 79.0 bits (193), Expect = 6e-14
Identities = 71/236 (30%), Positives = 88/236 (37%), Gaps = 62/236 (26%)
Query: 1980 YSATGECKC---NTGFNGTACEM-----CWPGRFGPDCLPCGCSD-----HGQCDDGITG 2026
YSAT C N F C+ C G G +C C HG C T
Sbjct: 203 YSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC----TV 258
Query: 2027 SGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENNTCECNLDYEGDGITCTVVDF 2085
G+C C GW G CD C P P H +C E C C ++ G
Sbjct: 259 PGECRCSYGWQGRFCDE-------CVPYPGCVHGSCVEPWQCNCETNWGG--------LL 303
Query: 2086 CKQDNGGCAKVARCSQKGTKVS-------CSCQKGYKGDG-----HSCTEIDPCADGLNG 2133
C +D C C+ GT ++ C+C GY G H+CT +PCA+G G
Sbjct: 304 CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTS-NPCANG--G 360
Query: 2134 GCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVD 2189
CHE P +C C S + G C L ID C + C A CVD
Sbjct: 361 SCHE-------VPSGFECHCPSGW--SGPTC---ALDIDECA--SNPCAAGGTCVD 402
Score = 78.2 bits (191), Expect = 1e-13
Identities = 74/274 (27%), Positives = 107/274 (39%), Gaps = 38/274 (13%)
Query: 1336 CCAGFFGPQCQ-PCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
C +G+ GP C A N C G C+D V+G C C E + G C+ G
Sbjct: 373 CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE-CICPEQWVGATCQLDANECEGKP 431
Query: 1395 CDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGTA 1454
C A SC + +G CDC GW+G++C ++C G C C +G
Sbjct: 432 CLNAFSC------KNLIGGYYCDCIPGWKGINCH--INVNDCRGQCQHGGTCKDLVNG-Y 482
Query: 1455 SCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
C C GF G + E ++ C + C+ G C C G++G +C E+
Sbjct: 483 QCVCPRGFGGRH---CELERDECASSPCHSGGLCEDLADGFH-CHCPQGFSGP--LC-EV 535
Query: 1515 NPCLENHGGCDKNAEC-TQTGPNQAAC-------NC-LPAYTGDGKVCTLINVCLTKNG- 1564
+ L C A C G AC NC +P G C +I+ C + G
Sbjct: 536 DVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGP 595
Query: 1565 ---GCSEFAICNHTGQVERTCTCKPNYIGDGFTC 1595
G + +C G+ C +P G F+C
Sbjct: 596 GMPGTAASGVCGPHGR----CVSQP---GGNFSC 622
Score = 77.0 bits (188), Expect = 2e-13
Identities = 80/297 (26%), Positives = 105/297 (35%), Gaps = 68/297 (22%)
Query: 113 PGGAGSP-CNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGV- 170
PG A S C G C GN +C C GF GT C DD L G C + C+ V
Sbjct: 598 PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCL-GQPCRNGGTCIDEVD 656
Query: 171 -----CNSGLDG--------------------------DGTCECYSAYTGPKCDKPIPEC 199
C SG +G D C C + G C +C
Sbjct: 657 AFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQC 716
Query: 200 AALLCPENSRCSPSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNR 259
A C C S + C C P ++G + CL C C G +
Sbjct: 717 DAYTCSNGGTCYDSGD---TFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGAS- 772
Query: 260 HSCTCQEGYRG-----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNF 314
SC C++G+ G + C P+ PC N G C DG CEC +
Sbjct: 773 FSCICRDGWEGRTCTHNTNDCNPL-PC-YNGGIC--------VDGVNWFRCECAPGF--- 819
Query: 315 VPGVGCSMT-DICKSDNPCHRNANCT--------TVAPGRTECICQKGYVGDGLTCY 362
G C + D C+S +PC A C + PGR CQ+ +G G +C+
Sbjct: 820 -AGPDCRINIDECQS-SPCAYGATCVDEINGYRCSCPPGRAGPRCQE-VIGFGRSCW 873
Score = 73.9 bits (180), Expect = 2e-12
Identities = 63/235 (26%), Positives = 87/235 (37%), Gaps = 56/235 (23%)
Query: 134 GTCSCQEGFGGTACETCADDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCD 193
G +C +G+ G C+ C CN +HG C G C C + G CD
Sbjct: 227 GNKACMDGWMGKECKEAV--------CKQGCNLLHGGCTV----PGECRCSYGWQGRFCD 274
Query: 194 K--PIPECAALLCPENSRCSPSTEDENKLECKCLPNYRG-----DGKYCDPINPCLRKIC 246
+ P P C C E +C C N+ G D YC +PC
Sbjct: 275 ECVPYPGCVHGSCVE------------PWQCNCETNWGGLLCDKDLNYCGSHHPCTN--- 319
Query: 247 HPHAHCTYLGPNRHSCTCQEGYRG----DGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQ 302
C P+++ CTC +GY G + +PC N G+C ++ P
Sbjct: 320 --GGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPC-ANGGSC--------HEVPSG 368
Query: 303 SHCECKEHYQNFVPGVGCSM-TDICKSDNPCHRNANCTTVAPGRTECICQKGYVG 356
C C + G C++ D C S NPC C G ECIC + +VG
Sbjct: 369 FECHCPSGWS----GPTCALDIDECAS-NPCAAGGTCVDQVDG-FECICPEQWVG 417
Score = 73.2 bits (178), Expect = 3e-12
Identities = 71/290 (24%), Positives = 104/290 (35%), Gaps = 48/290 (16%)
Query: 717 RYCNATVKIPKC------------CKGFYG-----PDCNQCPGGFSNPCSGNGQCADSLG 759
R+C+ V P C C+ +G D N C G +PC+ G C ++
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYC--GSHHPCTNGGTCINAEP 328
Query: 760 GNGTCICEEGFQGSQCQFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSA 819
C C +G+ G C+ P C +G + + S C C G +
Sbjct: 329 DQYRCTCPDGYSGRNCEKAEHACTSNP-------CANGGSCHEVPSGFEC---HCPSGWS 378
Query: 820 GRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGC 879
G C C C TC CIC + G T + + C G
Sbjct: 379 GPTCALDIDECAS--NPCAAGGTCVDQVDGFECICPEQWVG-ATCQLDANECEGKP---- 431
Query: 880 SRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCHDNASCLYVGPGQNEC 938
NA K G + C C GW G +C +N+C G C +C + G +C
Sbjct: 432 CLNAFSCKNLIGGYYCDCIPGW--KGINCHINVNDC----RGQCQHGGTCKDLVNGY-QC 484
Query: 939 ECKKGFRGNGIDCEPITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
C +GF G + E C + CH C+ + G + C C +G+ G
Sbjct: 485 VCPRGFGGRHCELER-DEC--ASSPCHSGGLCEDLADG-FHCHCPQGFSG 530
Score = 73.2 bits (178), Expect = 3e-12
Identities = 70/290 (24%), Positives = 94/290 (32%), Gaps = 55/290 (18%)
Query: 100 CCPGRWGPDCIECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPS 159
C PG G +C C G+C + + G C C GFGG CE D+ P
Sbjct: 449 CIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGY-QCVCPRGFGGRHCELERDECASSPC 507
Query: 160 CSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSPSTEDENK 219
S G+C DG C C ++GP C+ + C C +RC E
Sbjct: 508 HSG------GLCEDLADGFH-CHCPQGFSGPLCEVDVDLCEPSPCRNGARC---YNLEGD 557
Query: 220 LECKCLPNYRGDGKYCD-PINPC-----------------------LRKICHPHAHCTYL 255
C C ++ GK C P PC +C PH C
Sbjct: 558 YYCACPDDF--GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 256 GPNRHSCTCQEGYRGDGQVCLPVDPCQINFGNC---PTKSTVCKYDGPGQSHCECKEHYQ 312
SC C G+ G C N +C P ++ D C C ++
Sbjct: 616 PGGNFSCICDSGFTG--------TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWE 667
Query: 313 NFVPGVGCSMTDICKSDNPCHRNANCTTVAPGRTECICQKGYVGDGLTCY 362
G C +PCH C + C C G+ G TC+
Sbjct: 668 ----GELCDTNPNDCLPDPCHSRGRCYDLV-NDFYCACDDGW--KGKTCH 710
Score = 72.8 bits (177), Expect = 4e-12
Identities = 91/343 (26%), Positives = 130/343 (37%), Gaps = 84/343 (24%)
Query: 1876 GIDCLLIDPTLGGRCDTFTTFDASGECGS--CVNTPSC------------PRWSKPKGVK 1921
G +C+ + +G C DA+ EC C+N SC P W KG+
Sbjct: 406 GFECICPEQWVGATCQ----LDAN-ECEGKPCLNAFSCKNLIGGYYCDCIPGW---KGIN 457
Query: 1922 QKCLYNLPFKRNLEGCRERCS-------LVIQIPRCC-KGYFGRDCQA----CPGGPDAP 1969
N+ CR +C LV C +G+ GR C+ C +P
Sbjct: 458 CHI--------NVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECAS---SP 506
Query: 1970 CNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD-CLPCGCSDHGQCDDGITGSG 2028
C++ G+C D C C GF+G CE+ D C P C + +C + + G
Sbjct: 507 CHSGGLCEDLADGF-HCHCPQGFSGPLCEV------DVDLCEPSPCRNGARCYN-LEGDY 558
Query: 2029 QCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNTCECNLDYEGDGITCTVVDFCKQ 2088
C C + G +C +V PC A C+ + C + G G+ T
Sbjct: 559 YCACPDDFGGKNC-------SVPREPCPGGA-CRVIDGCGSD---AGPGMPGTAA----- 602
Query: 2089 DNGGCAKVARC-SQKGTKVSCSCQKGYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPG 2147
+G C RC SQ G SC C G+ G + ID C L C TC +
Sbjct: 603 -SGVCGPHGRCVSQPGGNFSCICDSGFTGT-YCHENIDDC---LGQPCRNGGTC-IDEVD 656
Query: 2148 KHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKCVDL 2190
+C C S + G+ + P CL D CH+ +C DL
Sbjct: 657 AFRCFCPSGWEGELCDTNPND-----CLPD--PCHSRGRCYDL 692
Score = 69.7 bits (169), Expect = 3e-11
Identities = 79/304 (25%), Positives = 113/304 (37%), Gaps = 64/304 (21%)
Query: 715 CARYCNATVKIPKCCKGFYGPDCNQ--CPGGFSNPCSGNGQCADSLGGNGTCICEEGFQG 772
C +Y N C G+ G +C + C G + +G C G C C G+QG
Sbjct: 223 CDQYGNKA-----CMDGWMGKECKEAVCKQGCNLL---HGGCTVP----GECRCSYGWQG 270
Query: 773 SQCQFC------------------SDPNKYGPRCNKK---CLCVH-----GTCNNRIDSD 806
C C + N G C+K C H GTC N
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQ 330
Query: 807 GACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCICKAGYEGDGTLCS 866
C TC DG +GR C+K AC C +C C C +G+ G T
Sbjct: 331 YRC---TCPDGYSGRNCEKAEHACTS--NPCANGGSCHEVPSGFECHCPSGWSGP-TCAL 384
Query: 867 EMDPCTGLTPGGCSRNAECIKTGTGTHTCVCQQGWTGNGRDCS-EINNCLLPSAGGCHDN 925
++D C C+ C+ G C+C + W G C + N C C +
Sbjct: 385 DIDECAS---NPCAAGGTCVDQVDG-FECICPEQWV--GATCQLDANEC---EGKPCLNA 435
Query: 926 ASCLYVGPGQNECECKKGFRGNGIDCE-PITSCLEQTGKCHPLASCQSTSSGVWSCVCQE 984
SC + G C+C G++ GI+C + C G+C +C+ +G + CVC
Sbjct: 436 FSCKNL-IGGYYCDCIPGWK--GINCHINVNDC---RGQCQHGGTCKDLVNG-YQCVCPR 488
Query: 985 GYEG 988
G+ G
Sbjct: 489 GFGG 492
Score = 69.3 bits (168), Expect = 5e-11
Identities = 74/320 (23%), Positives = 102/320 (31%), Gaps = 87/320 (27%)
Query: 1336 CCAGFFGPQC----QPCPGNA--------------------QNVCFGNGICLDGVNGTGV 1371
C F G C +PCPG A VC +G C+ G
Sbjct: 562 CPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFS 621
Query: 1372 CECGEGFSGTACETCTEGKYGIHCDQACSCV----------------------------- 1402
C C GF+GT C + G C +C+
Sbjct: 622 CICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 1403 ----HGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNG-TCHTSANCLTNSDGTASCK 1457
GRC + D C CD GW+G C + E C+ TC C + D T C
Sbjct: 682 PCHSRGRC-YDLVNDFYCACDDGWKGKTCH--SREFQCDAYTCSNGGTCYDSGD-TFRCA 737
Query: 1458 CAAGFQGNGTICTAINAC---EISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
C G++G+ ++C NGG + + C C+ G+ G
Sbjct: 738 CPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS------CICRDGWEG-------- 783
Query: 1515 NPCLENHGGCDK----NAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGCSEFA 1570
C N C+ N G N C C P + G IN+ ++ C+ A
Sbjct: 784 RTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPD---CRINIDECQSSPCAYGA 840
Query: 1571 ICNHTGQVERTCTCKPNYIG 1590
C R C+C P G
Sbjct: 841 TCVDEINGYR-CSCPPGRAG 859
Score = 67.0 bits (162), Expect = 2e-10
Identities = 82/312 (26%), Positives = 107/312 (34%), Gaps = 85/312 (27%)
Query: 1950 CCKGYFGRDCQACPGGPDA-PCNNRGVCLDQYSATGECKCNTGFNGTACEMCWPGRFGPD 2008
C G+ G+ C + DA C+N G C D T C C G+ G+ C +
Sbjct: 700 CDDGWKGKTCHSREFQCDAYTCSNGGTCYDS-GDTFRCACPPGWKGSTCAVAK----NSS 754
Query: 2009 CLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTP-PCSAHATCKENNT- 2066
CLP C + G C G S C+C GW G +C C P PC C +
Sbjct: 755 CLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNT---NDCNPLPCYNGGICVDGVNW 810
Query: 2067 --CECNLDYEGDGITCTV-VDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKG------- 2116
CEC + G C + +D C+ + CA A C + CSC G G
Sbjct: 811 FRCECAPGFAGP--DCRINIDECQ--SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
Query: 2117 ---------------------DGHSCTEID-------------PC-----ADGLNGGCHE 2137
D +SC +D PC + L+ C
Sbjct: 867 GFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPL 926
Query: 2138 HATCKMTGPG---KHKCECKSHYVGDGLNCEPEQLPIDRCLQDNGQCHADAKC--VDLHF 2192
C PG + CE C E+ P CL +G H D C + LHF
Sbjct: 927 GQRCLEKAPGQCLRPPCEAWG-------ECGAEEPPSTPCLPRSG--HLDNNCARLTLHF 977
Query: 2193 ------QDTTVG 2198
Q TTVG
Sbjct: 978 NRDHVPQGTTVG 989
Score = 65.9 bits (159), Expect = 5e-10
Identities = 60/243 (24%), Positives = 85/243 (34%), Gaps = 38/243 (15%)
Query: 1334 RECCAGFFGPQCQPCPGNAQNVCF-GNGICLDGVNGTGVCECGEGFSGTACETCTEGKYG 1392
+ C G+ G +C+ + VC G + G G C C G+ G C+ C
Sbjct: 229 KACMDGWMGKECK------EAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYP-- 280
Query: 1393 IHCDQACSCVHGRCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDG 1452
CVHG C + C+C+ W G+ CD + C C+
Sbjct: 281 -------GCVHGSCVE----PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329
Query: 1453 TASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCL 1512
C C G+ G A +AC ++ C+ C G C C +G++G L
Sbjct: 330 QYRCTCPDGYSGRNCE-KAEHAC--TSNPCANGGSCHEVPSGFE-CHCPSGWSGP-TCAL 384
Query: 1513 EINPCLENHGGCDKNAECTQ-------TGPNQ---AACNCLPAYTGDGKVCTLINVCLTK 1562
+I+ C N C C P Q A C L A +GK C C
Sbjct: 385 DIDECASN--PCAAGGTCVDQVDGFECICPEQWVGATCQ-LDANECEGKPCLNAFSCKNL 441
Query: 1563 NGG 1565
GG
Sbjct: 442 IGG 444
Score = 65.9 bits (159), Expect = 5e-10
Identities = 84/324 (25%), Positives = 105/324 (32%), Gaps = 87/324 (26%)
Query: 1335 ECCAGFFGPQCQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIH 1394
+C G+ G C + + C G C D VNG C C GF G CE
Sbjct: 448 DCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGY-QCVCPRGFGGRHCEL--------- 497
Query: 1395 CDQACSCVHGRCNQG----PLGDG-SCDCDVGWRGVHCDNATTEDNCN-GTCHTSANCLT 1448
+ C C+ G L DG C C G+ G C+ D C C A C
Sbjct: 498 --ERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE--VDVDLCEPSPCRNGARCY- 552
Query: 1449 NSDGTASCKCAAGFQGN----------GTICTAINAC----------EISNGGCSAKADC 1488
N +G C C F G G C I+ C ++G C C
Sbjct: 553 NLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRC 612
Query: 1489 KRTTPGRRVCTCKAGYTGDGIVCLE-INPCL----ENHGGC-------------DKNAEC 1530
G C C +G+T G C E I+ CL N G C E
Sbjct: 613 VSQPGGNFSCICDSGFT--GTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGEL 670
Query: 1531 TQTGPNQAACNCLP-AYTGDGKVCTLIN--VCLTKNG----------------GCSEFAI 1571
T PN +CLP G+ L+N C +G CS
Sbjct: 671 CDTNPN----DCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGT 726
Query: 1572 CNHTGQVERTCTCKPNYIGDGFTC 1595
C +G R C C P + G TC
Sbjct: 727 CYDSGDTFR-CACPPGW--KGSTC 747
Score = 62.8 bits (151), Expect = 4e-09
Identities = 83/356 (23%), Positives = 127/356 (35%), Gaps = 51/356 (14%)
Query: 94 DYLQPRCCPGRWGPDCIECPGGA--GSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCA 151
D + C PG G C + +PC G+C G + +C C++G+ G C
Sbjct: 732 DTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV-GSGASFSCICRDGWEGRTCTHNT 790
Query: 152 DDNLFGPSCSSVCNCVHGVCNSGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCS 211
+D C+ + G+C G++ CEC + GP C I EC + C + C
Sbjct: 791 ND------CNPLPCYNGGICVDGVNWF-RCECAPGFAGPDCRINIDECQSSPCAYGATC- 842
Query: 212 PSTEDENKLECKCLPNYRGDGKYCDPINPCLRKICH---PHAHCTYLGPNRHSCTCQEGY 268
++ N C C P G C + R P H + + +SC C +G
Sbjct: 843 --VDEINGYRCSCPPGRAGPR--CQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGR 898
Query: 269 RGDGQVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQNFVPGVGCSMTDICKS 328
R +V PC + G S C P C K Q P
Sbjct: 899 RDCSKVWCGWKPCLLA-GQPEALSAQC----PLGQRCLEKAPGQCLRP------------ 941
Query: 329 DNPCHRNANCTTVAPGRTECICQKGYVGDG---LTCYGNIMERLRELNTEPRGKWQGRLT 385
PC C P T C+ + G++ + LT + N + P+G G +
Sbjct: 942 --PCEAWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFN-------RDHVPQGTTVGAIC 992
Query: 386 SFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAG 441
S I L A +L ++L D+ G + E+ V A+ +I G
Sbjct: 993 SGIRSLPATRAVARDRL----LVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQG 1044
Score = 60.5 bits (145), Expect = 2e-08
Identities = 56/215 (26%), Positives = 75/215 (34%), Gaps = 40/215 (18%)
Query: 780 DPNKYGPRCNKKC-----LCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYV 834
D N Y CNK C H TC+ + C DG G+ C + G
Sbjct: 199 DENYYSATCNKFCRPRNDFFGHYTCDQYGNK-------ACMDGWMGKECKEAVCKQG--- 248
Query: 835 QFCHI-HATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTH 893
C++ H C T C+ Y G C E P G G C +
Sbjct: 249 --CNLLHGGC-----TVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQ--------- 292
Query: 894 TCVCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEP 953
C C+ W G D ++N C S C + +C+ P Q C C G+ G +CE
Sbjct: 293 -CNCETNWGGLLCD-KDLNYC--GSHHPCTNGGTCINAEPDQYRCTCPDGYSGR--NCEK 346
Query: 954 ITSCLEQTGKCHPLASCQSTSSGVWSCVCQEGYEG 988
+ C SC SG + C C G+ G
Sbjct: 347 AEHAC-TSNPCANGGSCHEVPSG-FECHCPSGWSG 379
Score = 54.3 bits (129), Expect = 2e-06
Identities = 63/224 (28%), Positives = 84/224 (37%), Gaps = 32/224 (14%)
Query: 54 CPDGYTMITSGSVGVRDCRYTFEVRTYSLSLPGCRHI-CRK--------DYLQPRCCPGR 104
C +G T + SG+ CR +E RT + + C + C ++ + C PG
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Query: 105 WGPDC-IECPGGAGSPCNGRGSCAEGMEGNGTCSCQEGFGGTACETCADDNLFGPSC-SS 162
GPDC I SPC +C + + G CSC G G C+ FG SC S
Sbjct: 820 AGPDCRINIDECQSSPCAYGATCVDEINGY-RCSCPPGRAGPRCQEVIG---FGRSCWSR 875
Query: 163 VCNCVHGV-----CNSGLDGDGTCECYSAYTG--PKCDKPIPECAALLCPENSRCSPSTE 215
HG CNS DG +C + G P PE + CP RC
Sbjct: 876 GTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCL---- 931
Query: 216 DENKLECKCL----PNYRGDGKYCDPINPCLRKICHPHAHCTYL 255
K +CL + G P PCL + H +C L
Sbjct: 932 --EKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCARL 973
Score = 50.4 bits (119), Expect = 2e-05
Identities = 59/233 (25%), Positives = 80/233 (34%), Gaps = 48/233 (20%)
Query: 1386 CTEGKYGIHCDQACSCVHGRCNQGPLGDGSCD------CDVGWRGVHCDNATTEDNCN-- 1437
C E Y C++ C R G +CD C GW G C A + CN
Sbjct: 198 CDENYYSATCNKFC-----RPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLL 252
Query: 1438 -GTCHTSANCLTNSDGTASCKCAAGFQGN-GTICTAINACEISNGGCSAKADCKRTTPGR 1495
G C C+C+ G+QG C C +G C P +
Sbjct: 253 HGGCTV----------PGECRCSYGWQGRFCDECVPYPGC--VHGSC--------VEPWQ 292
Query: 1496 RVCTCKAGYTGDGIVC-LEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCT 1554
C C+ + G++C ++N C +H C C P+Q C C Y+ G+ C
Sbjct: 293 --CNCETNW--GGLLCDKDLNYC-GSHHPCTNGGTCINAEPDQYRCTCPDGYS--GRNCE 345
Query: 1555 LINVCLTKNGGCSEFAICNHTGQVERTCTCKPNYIGDGFTCRGSIYQELPKNP 1607
T N C+ C H C C + G TC I E NP
Sbjct: 346 KAEHACTSN-PCANGGSC-HEVPSGFECHCPSGWSGP--TCALDI-DECASNP 393
Score = 48.9 bits (115), Expect = 6e-05
Identities = 45/193 (23%), Positives = 63/193 (32%), Gaps = 26/193 (13%)
Query: 1345 CQPCPGNAQNVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGIHCDQACSCVHG 1404
C P P C+ GIC+DGVN CEC GF+G C + I Q+ C +G
Sbjct: 793 CNPLP------CYNGGICVDGVNWFR-CECAPGFAGPDC------RINIDECQSSPCAYG 839
Query: 1405 RCNQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNS----DGTASCKCAA 1460
+ C C G G C +C + + + SC+C
Sbjct: 840 ATCVDEINGYRCSCPPGRAGPRCQEVI---GFGRSCWSRGTPFPHGSSWVEDCNSCRCLD 896
Query: 1461 GFQGNGTI------CTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDGIVCLEI 1514
G + + C E + C C PG+ + + G
Sbjct: 897 GRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPPS 956
Query: 1515 NPCLENHGGCDKN 1527
PCL G D N
Sbjct: 957 TPCLPRSGHLDNN 969
Score = 44.3 bits (103), Expect = 0.002
Identities = 54/241 (22%), Positives = 78/241 (32%), Gaps = 40/241 (16%)
Query: 1335 ECCAGFFGPQCQPCPGNAQ-NVCFGNGICLDGVNGTGVCECGEGFSGTACETCTEGKYGI 1393
EC GF GP C+ Q + C C+D +NG C C G +G C+ +G
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR-CSCPPGRAGPRCQEVI--GFGR 870
Query: 1394 HC-DQACSCVHGR-----CNQGPLGDGSCDCDVGWRG-VHCDNATTEDNCNGTCHTSANC 1446
C + HG CN DG DC W G C A + + C C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRC 930
Query: 1447 LTNSDGTASCKCAAGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTG 1506
L + G + C A +C P C ++G+
Sbjct: 931 LEKAPG-----------------------QCLRPPCEAWGECGAEEPPSTPCLPRSGHLD 967
Query: 1507 DGIVCLEINPCLENHGGCDKNAECTQTGPNQAACNCLPAYTGDGKVCTLINVCLTKNGGC 1566
+ L + H D + T G + LPA + L+ +C + G
Sbjct: 968 NNCARLTL------HFNRDHVPQGTTVGAICSGIRSLPATRAVARDRLLVLLCDRASSGA 1021
Query: 1567 S 1567
S
Sbjct: 1022 S 1022
Score = 39.7 bits (91), Expect = 0.038
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 8/54 (14%)
Query: 727 KCCKGFYGPDC----NQCPGGFSNPCSGNGQCADSLGGNGTCICEEGFQGSQCQ 776
+C GF GPDC ++C S+PC+ C D + G C C G G +CQ
Sbjct: 814 ECAPGFAGPDCRINIDECQ---SSPCAYGATCVDEINGY-RCSCPPGRAGPRCQ 863
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,898,563
Number of Sequences: 37866
Number of extensions: 6173118
Number of successful extensions: 29051
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 283
Number of HSP's that attempted gapping in prelim test: 12759
Number of HSP's gapped (non-prelim): 6871
length of query: 2551
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2432
effective length of database: 13,741,464
effective search space: 33419240448
effective search space used: 33419240448
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.