Guide to the Human Genome
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Search of human proteins with 5901898

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5901898 leucine rich repeat containing 23 isoform b [Homo
sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5901898 leucine rich repeat containing 23 isoform b [Homo sap...   637   0.0  
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s...   508   e-144
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa...   508   e-144
gi|21389483 leucine-rich repeats and guanylate kinase domain con...   110   1e-24
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap...    65   8e-11
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           59   7e-09
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    56   4e-08
gi|193083139 leucine rich repeat containing 32 precursor [Homo s...    55   1e-07
gi|5031707 leucine rich repeat containing 32 precursor [Homo sap...    55   1e-07
gi|62912470 leucine-rich repeat-containing G protein-coupled rec...    54   2e-07
gi|153792305 leucine rich repeat containing 58 [Homo sapiens]          53   3e-07
gi|4503743 flightless I homolog [Homo sapiens]                         52   7e-07
gi|41349454 proline arginine-rich end leucine-rich repeat protei...    51   1e-06
gi|4506041 proline arginine-rich end leucine-rich repeat protein...    51   1e-06
gi|4505047 lumican precursor [Homo sapiens]                            51   2e-06
gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo...    49   4e-06
gi|238908508 leucine-rich repeat and death domain-containing pro...    49   6e-06
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]     49   6e-06
gi|19718734 toll-like receptor 2 [Homo sapiens]                        49   7e-06
gi|66472382 nischarin [Homo sapiens]                                   49   7e-06
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  47   2e-05
gi|27436867 slit and trk like 4 protein [Homo sapiens]                 47   3e-05
gi|15529980 leucine rich repeat containing 46 [Homo sapiens]           46   4e-05
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    45   8e-05
gi|24308207 leucine rich repeat containing 47 [Homo sapiens]           45   8e-05
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    45   8e-05
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    45   8e-05
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]    45   1e-04
gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo...    44   1e-04
gi|239752518 PREDICTED: similar to leucine rich repeat containin...    44   2e-04

>gi|5901898 leucine rich repeat containing 23 isoform b [Homo
           sapiens]
          Length = 312

 Score =  637 bits (1642), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLRRSKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLEIHHNLRPRICSVP 300
           SREMKSLQYLNLRRSKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLEIHHNLRPRICSVP
Sbjct: 241 SREMKSLQYLNLRRSKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLEIHHNLRPRICSVP 300

Query: 301 VLWAVWGAEWGA 312
           VLWAVWGAEWGA
Sbjct: 301 VLWAVWGAEWGA 312


>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score =  508 bits (1309), Expect = e-144
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLR 253
           SREMKSLQYLNLR
Sbjct: 241 SREMKSLQYLNLR 253


>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score =  508 bits (1309), Expect = e-144
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60
           MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL
Sbjct: 1   MSDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMKEGLSLL 60

Query: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120
           CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA
Sbjct: 61  CKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKA 120

Query: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180
           DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS
Sbjct: 121 DGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLIS 180

Query: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240
           LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF
Sbjct: 181 LHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGF 240

Query: 241 SREMKSLQYLNLR 253
           SREMKSLQYLNLR
Sbjct: 241 SREMKSLQYLNLR 253


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score =  110 bits (276), Expect = 1e-24
 Identities = 81/249 (32%), Positives = 131/249 (52%), Gaps = 6/249 (2%)

Query: 16  DSEKEEDEKETEEGEDYRKEGEEFP-EEWLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKL 74
           DS+ +ED+ E E G +   E E    EE     L E+ + + L  L ++G+G    Y+ L
Sbjct: 73  DSDGDEDQGEGEAGSEESSESEMLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQVYLNL 132

Query: 75  EVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELP 134
            +   +L D+ +L  Y+HL+ +D+S N + DLS ++ + +LL L A  N L +    + P
Sbjct: 133 TLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPP 192

Query: 135 -YLQIASFAYNQITDTEGIS-HPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLE 192
             L+ A F++NQI++   +S +  L  L L GN I  ++GL  E   +L  + L  N++ 
Sbjct: 193 KNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGL--EMCNNLIHLSLANNKIT 250

Query: 193 STLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
           +  G+N   +K L L+ N ++ + GLEDL  L  L L  NQI +L G       L+ +NL
Sbjct: 251 TINGLNKLPIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSLQGLENH-DLLEVINL 309

Query: 253 RRSKTLAFR 261
             +K    R
Sbjct: 310 EDNKIAELR 318


>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
           sapiens]
          Length = 360

 Score = 65.1 bits (157), Expect = 8e-11
 Identities = 74/275 (26%), Positives = 119/275 (43%), Gaps = 40/275 (14%)

Query: 2   SDEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEFPEEWLPTPLTEDMMK------- 54
           S+E   E+ +        +  E+  ++GE+    GEE PEE    P+  + +        
Sbjct: 24  SEESGDEEGKKHSSGIVADLSEQSLKDGEE---RGEEDPEEEHELPVDMETINLDRDAED 80

Query: 55  -----------EGLSLLCKTGN-----GLAHAYVKLE----VKERDLTD-----IYLLRS 89
                      EG  +L K         L      LE    ++E DL D     I  L +
Sbjct: 81  VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 140

Query: 90  YIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQ-MNELPYLQIASFAYNQITD 148
              L  +DIS N L ++  ++ LT L  L    N++   + ++ L  LQ+     N+I  
Sbjct: 141 LTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRA 200

Query: 149 TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI-NLPKLKNLY 206
            E I     LE+L L  N I  +  LD   L +L  + ++ N+L    G+ NL  L+ LY
Sbjct: 201 IENIDTLTNLESLFLGKNKITKLQNLDA--LTNLTVLSMQSNRLTKIEGLQNLVNLRELY 258

Query: 207 LAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFS 241
           L+ N ++ +EGLE+ + LT L +  N+I  +   S
Sbjct: 259 LSHNGIEVIEGLENNNKLTMLDIASNRIKKIENIS 293


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 55/180 (30%), Positives = 84/180 (46%), Gaps = 29/180 (16%)

Query: 73  KLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNE 132
           +L ++ + LT   ++    HLR ++   N +T +  ++ L  L+ L              
Sbjct: 94  RLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISL-------------- 139

Query: 133 LPYLQIASFAYNQITDTEGISHPR-LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL 191
                      NQI +  G+S  R L  L L  N I  ++ L  E L SL  ++L GNQ+
Sbjct: 140 -------DLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNL--ENLKSLDVLDLHGNQI 190

Query: 192 ESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYL 250
                IN L +L+ L LA+N L  V+ L  L +LT L+LR NQI     F R++ +L  L
Sbjct: 191 TKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT----FVRDVDNLPCL 246



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 21/229 (9%)

Query: 60  LCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLK 119
           +C   NG  H  + L  +   +T I  + +   L  +D+ +N + ++S L+ L  L  L 
Sbjct: 104 VCPIINGEDHLRL-LNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLL 162

Query: 120 ADGNRLRS-AQMNELPYLQIASFAYNQITDTEGISHP-RLETLNLKGNSIHMVTGLDPEK 177
              NR++  + +  L  L +     NQIT  E I+H   L  LNL  N +  V  L+   
Sbjct: 163 LGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNG-- 220

Query: 178 LISLHTVELRGNQLESTLGI-NLPKLKNLYLAQNMLK---KVEGLEDLSNLTTLHLRDNQ 233
           L SL  + LR NQ+     + NLP L++L+L+ N +     V  L D S+L+ +    N 
Sbjct: 221 LDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 280

Query: 234 IDTLSGFS----REMKSLQYLNLRR--------SKTLAFRPDQTPRGSH 270
           I   S +     + M  L+ L+++R        +  LA + ++  R SH
Sbjct: 281 IAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESH 329


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 35/84 (41%), Positives = 51/84 (60%), Gaps = 3/84 (3%)

Query: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
           L  +NL  N+I  +  +D   + +L  ++L  NQ+    G+N L KL  L L+ N++ KV
Sbjct: 45  LHAVNLHCNNISKIEAID--HIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLITKV 102

Query: 216 EGLEDLSNLTTLHLRDNQIDTLSG 239
           EGLE+L NLT L++  N ID LSG
Sbjct: 103 EGLEELINLTRLNVSYNHIDDLSG 126



 Score = 28.5 bits (62), Expect = 8.0
 Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 5/79 (6%)

Query: 81  LTDIYLLRSYIHLRYVDISENHLTDLS---PLNYLTH-LLWLKADGNRLRSAQMNELPYL 136
           +T +  L   I+L  +++S NH+ DLS   PL+ + H L ++    NR+ S   + L  +
Sbjct: 99  ITKVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIH-HLLQCM 157

Query: 137 QIASFAYNQITDTEGISHP 155
               F  N I + +G  +P
Sbjct: 158 VGLHFLTNLILEKDGDDNP 176


>gi|193083139 leucine rich repeat containing 32 precursor [Homo
           sapiens]
          Length = 662

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 58/194 (29%), Positives = 92/194 (47%), Gaps = 31/194 (15%)

Query: 90  YIHLRYVDISENHLTDLSP--LNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQIT 147
           Y  LR++D+S N ++ L P     LTHL  L    NRL  A         +++     + 
Sbjct: 72  YTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMA-------TALSAGGLGPL- 123

Query: 148 DTEGISHPRLETLNLKGNSIHMVTGLDPEKLI----SLHTVELRGNQLESTLG---INLP 200
                  PR+ +L+L GNS++  +GL  E+L+    SLHT+ L  N L         ++P
Sbjct: 124 -------PRVTSLDLSGNSLY--SGL-LERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173

Query: 201 KLKNLYLAQNMLKKVE--GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRSKTL 258
            L+ L L  N+L  +E    E L  LT L+L  N +  +S FS  ++ L+ L+L  +   
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS--LQQLRVLDLSCNSIE 231

Query: 259 AFRPDQTPRGSHHM 272
           AF+    P+    +
Sbjct: 232 AFQTASQPQAEFQL 245



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 41/177 (23%)

Query: 93  LRYVDISENHLTDLSPLNY--LTHLLWLKADGNR-----------------------LRS 127
           LR + +  N L DL P  +  L  L  L   GNR                       LRS
Sbjct: 388 LRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRS 447

Query: 128 AQM--NELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVE 185
             +  NE+  L+  +F +  +T+ +  S+P LE          + TG       SL  + 
Sbjct: 448 LSLVDNEIELLRAGAFLHTPLTELDLSSNPGLE----------VATGALGGLEASLEVLA 497

Query: 186 LRGNQLESTLGINLPK---LKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG 239
           L+GN L   L ++LP    LK L LA+N L  +       +L  L LR+N    L G
Sbjct: 498 LQGNGL-MVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPG 553



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 17/173 (9%)

Query: 93  LRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIA----SFAYNQITD 148
           L ++++S N LT +S  + L  L  L    N + + Q    P  +          N++  
Sbjct: 199 LTHLNLSRNSLTCISDFS-LQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLH 257

Query: 149 TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLE------STLGINLPK 201
              ++  PRL  LNL  N I + TG  P+    +H      + L       +  G  L +
Sbjct: 258 FPDLAALPRLIYLNLSNNLIRLPTG-PPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQ 316

Query: 202 LKNLYLAQNMLKKVEG--LEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
           L NL L+ N ++ +    LE L++L  L+L  N + T    +R + SL  L L
Sbjct: 317 LLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFE--ARRLGSLPCLML 367


>gi|5031707 leucine rich repeat containing 32 precursor [Homo
           sapiens]
          Length = 662

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 58/194 (29%), Positives = 92/194 (47%), Gaps = 31/194 (15%)

Query: 90  YIHLRYVDISENHLTDLSP--LNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQIT 147
           Y  LR++D+S N ++ L P     LTHL  L    NRL  A         +++     + 
Sbjct: 72  YTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMA-------TALSAGGLGPL- 123

Query: 148 DTEGISHPRLETLNLKGNSIHMVTGLDPEKLI----SLHTVELRGNQLESTLG---INLP 200
                  PR+ +L+L GNS++  +GL  E+L+    SLHT+ L  N L         ++P
Sbjct: 124 -------PRVTSLDLSGNSLY--SGL-LERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173

Query: 201 KLKNLYLAQNMLKKVE--GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRSKTL 258
            L+ L L  N+L  +E    E L  LT L+L  N +  +S FS  ++ L+ L+L  +   
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS--LQQLRVLDLSCNSIE 231

Query: 259 AFRPDQTPRGSHHM 272
           AF+    P+    +
Sbjct: 232 AFQTASQPQAEFQL 245



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 50/177 (28%), Positives = 71/177 (40%), Gaps = 41/177 (23%)

Query: 93  LRYVDISENHLTDLSPLNY--LTHLLWLKADGNR-----------------------LRS 127
           LR + +  N L DL P  +  L  L  L   GNR                       LRS
Sbjct: 388 LRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRS 447

Query: 128 AQM--NELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVE 185
             +  NE+  L+  +F +  +T+ +  S+P LE          + TG       SL  + 
Sbjct: 448 LSLVDNEIELLRAGAFLHTPLTELDLSSNPGLE----------VATGALGGLEASLEVLA 497

Query: 186 LRGNQLESTLGINLPK---LKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG 239
           L+GN L   L ++LP    LK L LA+N L  +       +L  L LR+N    L G
Sbjct: 498 LQGNGL-MVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPG 553



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 46/173 (26%), Positives = 75/173 (43%), Gaps = 17/173 (9%)

Query: 93  LRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIA----SFAYNQITD 148
           L ++++S N LT +S  + L  L  L    N + + Q    P  +          N++  
Sbjct: 199 LTHLNLSRNSLTCISDFS-LQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLH 257

Query: 149 TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLE------STLGINLPK 201
              ++  PRL  LNL  N I + TG  P+    +H      + L       +  G  L +
Sbjct: 258 FPDLAALPRLIYLNLSNNLIRLPTG-PPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQ 316

Query: 202 LKNLYLAQNMLKKVEG--LEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
           L NL L+ N ++ +    LE L++L  L+L  N + T    +R + SL  L L
Sbjct: 317 LLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFE--ARRLGSLPCLML 367


>gi|62912470 leucine-rich repeat-containing G protein-coupled
           receptor 6 isoform 1 [Homo sapiens]
          Length = 967

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 56/180 (31%), Positives = 86/180 (47%), Gaps = 14/180 (7%)

Query: 95  YVDISENHLTDLSP--LNYLTHLLWLKADGNRLR---SAQMNELPYLQIASFAYNQI--T 147
           Y+D+S N+LT+L P   ++L  L  L+  GN L        + L  L+I     NQ+   
Sbjct: 70  YLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGI 129

Query: 148 DTEGI-SHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLES---TLGINLPKLK 203
             E +   P L++L L  N I +V     E L SL  + L  N L         NLP L+
Sbjct: 130 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 189

Query: 204 NLYLAQNMLKKVE--GLEDLSNLTTLHLRDNQIDTLSGFSRE-MKSLQYLNLRRSKTLAF 260
            + LA N +  +     ++L++L  LHL +N+I  L   S E + +L+ L+L  +K   F
Sbjct: 190 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF 249



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 46/154 (29%), Positives = 71/154 (46%), Gaps = 15/154 (9%)

Query: 116 LWLKADGNRLR-SAQMNEL-PYLQIASFAYNQITDTE-GISHPR--LETLNLKGNSIHMV 170
           + L AD + L  SA   +L P       + N +T+ + G+ H    LE L L GN +  +
Sbjct: 46  IMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHI 105

Query: 171 TGLDPEKLISLHTVELRGNQL---ESTLGINLPKLKNLYLAQNMLKKV--EGLEDLSNLT 225
            G     L SL  + L+ NQL    +     LP L++L L  N++  V     E LS+L 
Sbjct: 106 PGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLR 165

Query: 226 TLHLRDNQIDTLSGFSREMKSLQYLNLRRSKTLA 259
            L L DN +  +      +++L  L   ++ TLA
Sbjct: 166 HLWLDDNALTEI-----PVRALNNLPALQAMTLA 194



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 49/217 (22%), Positives = 86/217 (39%), Gaps = 42/217 (19%)

Query: 85  YLLRSYIHLRYVDISENHLTDLSPLNY--LTHLLWLKADGNRLRS--AQMNELPYLQIAS 140
           Y  ++   L  + +  N +  L   ++  L +L  L  + N+L+     +  L  LQ   
Sbjct: 204 YAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELG 263

Query: 141 FAYNQIT---DTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQ------- 190
           F  N I    +   + +P L+T++   N I  V     + L  LHT+ L G         
Sbjct: 264 FHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD 323

Query: 191 -------------------LESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRD 231
                              L S +   LP+L+ L L+ N ++++  L     L  + L+ 
Sbjct: 324 LKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQH 383

Query: 232 NQI-----DTLSGFSREMKSLQYLNLRRSKTLAFRPD 263
           N+I     DT S    ++ SLQ L+L  +   +  P+
Sbjct: 384 NRIWEIGADTFS----QLSSLQALDLSWNAIRSIHPE 416



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 37/144 (25%), Positives = 57/144 (39%), Gaps = 33/144 (22%)

Query: 96  VDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTE----- 150
           +DI E    DL     L  L   +A    L S    +LP L++   ++NQI +       
Sbjct: 316 MDIQE--FPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRC 373

Query: 151 ------GISHPR--------------LETLNLKGNSIHMVTGLDPEKLISLHT---VELR 187
                 G+ H R              L+ L+L  N+I     + PE   +LH+   ++L 
Sbjct: 374 QKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIR---SIHPEAFSTLHSLVKLDLT 430

Query: 188 GNQLESTLGINLPKLKNLYLAQNM 211
            NQL +     L  L +L L  N+
Sbjct: 431 DNQLTTLPLAGLGGLMHLKLKGNL 454


>gi|153792305 leucine rich repeat containing 58 [Homo sapiens]
          Length = 371

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 63/219 (28%), Positives = 98/219 (44%), Gaps = 20/219 (9%)

Query: 43  WLPTPLTEDMMKEGLSLLCKTGNGLAHAYVKLEVKERDLTDI--YLLRSYIHLRYVDISE 100
           W    ++ + ++  L    +   G   A ++L +    L  +   L   + HL+ +D+S 
Sbjct: 18  WSRLSVSTETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSG 77

Query: 101 NHLTDLSP-LNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLET 159
           N LT L P L  L  L  L A  NRL        P       A + +  +       L+ 
Sbjct: 78  NALTALGPELLALRGLRTLLAKNNRLGG------PSALPKGLAQSPLCRS-------LQV 124

Query: 160 LNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLG--INLPKLKNLYLAQNMLKKV-E 216
           LNL GN    V     E L +L T+ L GNQL+S      NL  L+ LYL  N +K++  
Sbjct: 125 LNLSGNCFQEVPASLLE-LRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPP 183

Query: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRS 255
            L +L +L  L L DN+I ++     ++ SL+ L+L  +
Sbjct: 184 ELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNN 222


>gi|4503743 flightless I homolog [Homo sapiens]
          Length = 1269

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 53/179 (29%), Positives = 76/179 (42%), Gaps = 37/179 (20%)

Query: 93  LRYVDISENHLTDLSP-LNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAY-------- 143
           L Y+D+SEN L  L P +  L HL  L  +GN L  AQ+ +LP +      +        
Sbjct: 153 LLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQ 212

Query: 144 -NQITDTEGISH---------------------PRLETLNLKGNSIHMVTGLDPEKLISL 181
            N  T  EG+S+                     P L  LNL  N I  ++ L  ++ + +
Sbjct: 213 SNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELS-LCIDQWVHV 271

Query: 182 HTVELRGNQLES--TLGINLPKLKNLYLAQNMLK---KVEGLEDLSNLTTLHLRDNQID 235
            T+ L  NQL S  +    L KLK LYL  N L       G+  L+NL      +N ++
Sbjct: 272 ETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNLE 330



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 15/177 (8%)

Query: 93  LRYVDISENHLTDLS-PLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEG 151
           L  +D+S N LT+    L    ++L L    N + +   N+L ++ +    Y  +++   
Sbjct: 106 LSVLDLSHNQLTECPRELENAKNMLVLNLSHNSIDTIP-NQL-FINLTDLLYLDLSENRL 163

Query: 152 ISHP-------RLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQ-LESTLGINLPKLK 203
            S P        L+TL L GN +          + +L T+ LR  Q  +S L  +L  L 
Sbjct: 164 ESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLS 223

Query: 204 NLY---LAQNMLKKV-EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRSK 256
           NL    L+ N L +V E L  L +L  L+L  NQI  LS    +   ++ LNL R++
Sbjct: 224 NLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNLSRNQ 280


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 18/191 (9%)

Query: 79  RDLTDIYLLRSYIHLRYVDISENHLTDLSPLNY--LTHLLWLKADGNRLRSAQ---MNEL 133
           R+L  + ++   IH  Y+ +  N +T+L   ++   T L W+  D NR+R      + +L
Sbjct: 92  RNLRKVPVIPPRIH--YLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKL 149

Query: 134 PYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLES 193
           P L       NQ+ +        LE L L  N I  +      KL +L  ++L+ N+L  
Sbjct: 150 PGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSD 209

Query: 194 TLGI-------NLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTL-SGFSREMK 245
             G+        L  L  L LA N+L+K+      + +  L+L  N+I+T+ +G+ +   
Sbjct: 210 --GVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA-IHQLYLDSNKIETIPNGYFKSFP 266

Query: 246 SLQYLNLRRSK 256
           +L ++ L  +K
Sbjct: 267 NLAFIRLNYNK 277



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 14/126 (11%)

Query: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216
           L  +NL  N I  +     EKL  L  + +  NQLE         L+ L L+QN + ++ 
Sbjct: 128 LRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIP 187

Query: 217 G--LEDLSNLTTLHLRDNQI-------DTLSGFSREMKSLQYLNLRRSKTLAFRPDQTPR 267
                 L NL  L L+ N++       DT  G    +K+L  LNL  +  L   P + P 
Sbjct: 188 PGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG----LKNLMQLNLAHN-ILRKMPPRVPT 242

Query: 268 GSHHMY 273
             H +Y
Sbjct: 243 AIHQLY 248


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 18/191 (9%)

Query: 79  RDLTDIYLLRSYIHLRYVDISENHLTDLSPLNY--LTHLLWLKADGNRLRSAQ---MNEL 133
           R+L  + ++   IH  Y+ +  N +T+L   ++   T L W+  D NR+R      + +L
Sbjct: 92  RNLRKVPVIPPRIH--YLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKL 149

Query: 134 PYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLES 193
           P L       NQ+ +        LE L L  N I  +      KL +L  ++L+ N+L  
Sbjct: 150 PGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSD 209

Query: 194 TLGI-------NLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTL-SGFSREMK 245
             G+        L  L  L LA N+L+K+      + +  L+L  N+I+T+ +G+ +   
Sbjct: 210 --GVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA-IHQLYLDSNKIETIPNGYFKSFP 266

Query: 246 SLQYLNLRRSK 256
           +L ++ L  +K
Sbjct: 267 NLAFIRLNYNK 277



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 14/126 (11%)

Query: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216
           L  +NL  N I  +     EKL  L  + +  NQLE         L+ L L+QN + ++ 
Sbjct: 128 LRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIP 187

Query: 217 G--LEDLSNLTTLHLRDNQI-------DTLSGFSREMKSLQYLNLRRSKTLAFRPDQTPR 267
                 L NL  L L+ N++       DT  G    +K+L  LNL  +  L   P + P 
Sbjct: 188 PGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG----LKNLMQLNLAHN-ILRKMPPRVPT 242

Query: 268 GSHHMY 273
             H +Y
Sbjct: 243 AIHQLY 248


>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 12/115 (10%)

Query: 142 AYNQITDTEGI--SHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINL 199
           A+  +TD + +   H  LE   +KG            KL  L  + +  N L  ++G   
Sbjct: 85  AFENVTDLQWLILDHNLLENSKIKGRVF--------SKLKQLKKLHINHNNLTESVGPLP 136

Query: 200 PKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQI--DTLSGFSREMKSLQYLNL 252
             L++L L  N + K+   E L NLT +HL+ N++  D +S   + +KSL+YL+L
Sbjct: 137 KSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDL 191


>gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo
           sapiens]
          Length = 757

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 60/217 (27%), Positives = 93/217 (42%), Gaps = 24/217 (11%)

Query: 69  HAYVKLEVKERDLTDI--YLLRSYIHLRYVDISENHLTDLSP--LNYLTHLLWLKADGNR 124
           H   KL ++   +T I  Y  R    L  + +S N +T L P     L  L WL  + N 
Sbjct: 150 HDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNH 209

Query: 125 LRSAQ------MNELPYLQIASFAYNQITDTEGISH-PRLETLNLKGNSIHMVTGLDPEK 177
           L          +N L  L + +    ++ D     H PRL  L+L+GN IH +  L    
Sbjct: 210 LSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFIS 269

Query: 178 LISLHTVELRGNQL----ESTLGINLPKLKNLYLAQNMLKKVEGL--EDLSNLTTLHLRD 231
             +L  + +R N++    E+T    L KL  L L  N ++ +  L  +DL  L+ L+L  
Sbjct: 270 CSNLTVLVMRKNKINHLNENTFA-PLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSY 328

Query: 232 NQIDTLSG--FSREMK----SLQYLNLRRSKTLAFRP 262
           N I  +    F   +K    SL+ + +   +   FRP
Sbjct: 329 NPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRP 365


>gi|238908508 leucine-rich repeat and death domain-containing
           protein [Homo sapiens]
          Length = 860

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 46/174 (26%), Positives = 86/174 (49%), Gaps = 10/174 (5%)

Query: 89  SYIHLRYVDISENHLTDL--SPLNYLT-HLLWLKADGNRLRSAQMNELPYLQIASFAYNQ 145
           S I+L+Y+D+ +N +  +  S  N ++ H+L L  +       ++  L  LQ+   + NQ
Sbjct: 531 SLINLKYLDLGKNQIKKIPASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQ 590

Query: 146 IT--DTEGISHPRLETLNLKGNS-IHMVTGL-DPEKLISLHTVELRGNQLESTLG--INL 199
           +    ++  +   ++ LN   N  IH    L   + L  L+  +++G +L    G   N+
Sbjct: 591 LQKISSDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTRLPGELSNM 650

Query: 200 PKLKNLYLAQNMLKKV-EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
            +LK L ++ N ++++   + +L NL +LH  +NQI  L      +  LQ LNL
Sbjct: 651 TQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNL 704


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 50/178 (28%), Positives = 82/178 (46%), Gaps = 15/178 (8%)

Query: 93  LRYVDISENHLT--DLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTE 150
           L  + ++EN+L   D   L+ L  L+ L+ +GN L  A +N L +  + S AY ++   +
Sbjct: 416 LEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNK 475

Query: 151 GISHPR-----LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLEST-----LGINLP 200
               P+     +E L L+ N I  +T +       ++ + LR N++E         IN  
Sbjct: 476 FRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQE 535

Query: 201 KLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG--FSREMKSLQYLNLRRSK 256
            L+++ L+ N L  V      S L  L L  NQI+ + G  F      L+YL L  +K
Sbjct: 536 NLESIDLSYNKLYHVPSYLPKS-LLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNK 592



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 45/152 (29%), Positives = 72/152 (47%), Gaps = 17/152 (11%)

Query: 123 NRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLH 182
           N  R   +  L Y +I     N+I     I+   LE+++L  N ++ V    P+ L  LH
Sbjct: 506 NHTRKINVIVLRYNKIEE---NRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSL--LH 560

Query: 183 TVELRGNQLESTLGINL----PKLKNLYLAQNMLKKVEGLEDLS------NLTTLHLRDN 232
            V L GNQ+E   G       P L+ LYL+ N L   +G++ +S      +L  L L  N
Sbjct: 561 LV-LLGNQIERIPGYVFGHMEPGLEYLYLSFNKLAD-DGMDRVSFYGAYHSLRELFLDHN 618

Query: 233 QIDTLSGFSREMKSLQYLNLRRSKTLAFRPDQ 264
            + ++    +EMK+L +L L  +K     P++
Sbjct: 619 DLKSIPPGIQEMKALHFLRLNNNKIRNILPEE 650


>gi|19718734 toll-like receptor 2 [Homo sapiens]
          Length = 784

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 44/158 (27%), Positives = 68/158 (43%), Gaps = 16/158 (10%)

Query: 93  LRYVDISENHLTDLSPLNYLTHLLW-----LKADGNRLRSAQMNELPYLQIASFAYNQIT 147
           L Y+D+SEN + +    N      W     L    N L S +      L + +     I+
Sbjct: 362 LEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQNHLASLEKTGETLLTLKNLTNIDIS 421

Query: 148 DTEGISHP-------RLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLP 200
                S P       +++ LNL    IH VTG  P+   +L  +++  N L +   +NLP
Sbjct: 422 KNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPK---TLEILDVSNNNL-NLFSLNLP 477

Query: 201 KLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS 238
           +LK LY+++N L  +     L  L  L +  N I T S
Sbjct: 478 QLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFS 515



 Score = 32.7 bits (73), Expect = 0.42
 Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 156 RLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL------ESTLGINLPKLKNLYLAQ 209
           R++ + ++ + + +V  L  + L SL  ++L  N +       S      P L+ L L Q
Sbjct: 337 RVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQ 396

Query: 210 NML----KKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRSK 256
           N L    K  E L  L NLT + +  N   ++    +  + ++YLNL  ++
Sbjct: 397 NHLASLEKTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTR 447


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 31/85 (36%), Positives = 51/85 (60%), Gaps = 4/85 (4%)

Query: 155 PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN--LPKLKNLYLAQNML 212
           P++E L+L  N + +V  L  + L +L  ++L  N+L S  G++  L  +K L LA N+L
Sbjct: 310 PKIEFLDLSHNGLLVVDNL--QHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLL 367

Query: 213 KKVEGLEDLSNLTTLHLRDNQIDTL 237
           + + GL  L +L  L LRDN+I+ +
Sbjct: 368 ESLSGLHKLYSLVNLDLRDNRIEQM 392



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 31/127 (24%)

Query: 93  LRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI 152
           + ++D+S N L  +  L +L +L+ L                       +YN+++  EG+
Sbjct: 312 IEFLDLSHNGLLVVDNLQHLYNLVHL---------------------DLSYNKLSSLEGL 350

Query: 153 SHPRL---ETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGI----NLPKLKNL 205
            H +L   +TLNL GN +  ++GL   KL SL  ++LR N++E    +    +LP L+++
Sbjct: 351 -HTKLGNIKTLNLAGNLLESLSGL--HKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHV 407

Query: 206 YLAQNML 212
            L  N L
Sbjct: 408 SLLNNPL 414


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 2/83 (2%)

Query: 176 EKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQI 234
           EK + L  + L  N +     ++ L KL+ L L+ N + K+EG+E++ NL  L+L  N+I
Sbjct: 122 EKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEI 181

Query: 235 DTLS-GFSREMKSLQYLNLRRSK 256
           + +     +++KSL+ LNL+ +K
Sbjct: 182 EHIPVWLGKKLKSLRVLNLKGNK 204



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 10/116 (8%)

Query: 129 QMNELPYLQIASFAYNQITDTEGISHP-RLETLNLKGNSIHMVTGLDPEKLISLHTVELR 187
           ++++L  L+  + +YN+I+  EGI +   L+ LNL GN I  +     +KL SL  + L+
Sbjct: 142 KLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLK 201

Query: 188 GNQLESTLGIN----LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSG 239
           GN++ S   I+    L  L +L L +N    V  L      T  HLR   +++L G
Sbjct: 202 GNKISSLQDISKLKPLQDLISLILVEN---PVVTLPHYLQFTIFHLR--SLESLEG 252


>gi|27436867 slit and trk like 4 protein [Homo sapiens]
          Length = 837

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 144 NQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLE---STLGINLP 200
           +  TD EG     L+ L+L  N I ++ G     L +L  + L GNQ+E     +   L 
Sbjct: 395 SDFTDFEG-----LDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLH 449

Query: 201 KLKNLYLAQNMLKKVEG--LEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRRSK 256
            L+ LYL  N++K++     + + NL  L+L +N + +L  +      L  LNLR +K
Sbjct: 450 NLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNK 507


>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
          Length = 321

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 35/97 (36%), Positives = 54/97 (55%), Gaps = 4/97 (4%)

Query: 157 LETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKV 215
           L+T+ L    I  +  L  E L +LH++ L+GN+++    +  +P L+ L LA N +++V
Sbjct: 46  LQTVRLDREGITTIRNL--EGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQV 103

Query: 216 EGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
           E L DL  L  L L +N I+TL       +SL  LNL
Sbjct: 104 ENLLDLPCLQFLDLSENLIETLK-LDEFPQSLLILNL 139


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 55/215 (25%), Positives = 99/215 (46%), Gaps = 18/215 (8%)

Query: 86  LLRSYIHLRYVDISENHLTDLSPLNY-LTHLLWLKADGNRLRSAQ------MNELPYLQI 138
           L RS + LR   +S+N +T L    + L  L  L  + NR+R  +      +N L  L++
Sbjct: 186 LSRSLLTLR---LSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKL 242

Query: 139 ASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN 198
                +++TD       ++  L+L+ NS+  V       L +LH + L  N +       
Sbjct: 243 QRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKG 302

Query: 199 ---LPKLKNLYLAQNMLKKV--EGLEDLSNLTTLHLRDNQIDTLS-GFSREMKSLQYLNL 252
                KL  L L+ N L ++  E L +LS+L+ L L  N I  ++ G  + ++SL+ L+L
Sbjct: 303 WSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDL 362

Query: 253 RRSKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLE 287
             ++      D +  G+    D   ++ +F  K++
Sbjct: 363 DHNEISGTIEDTS--GAFSGLDSLSKLTLFGNKIK 395



 Score = 28.9 bits (63), Expect = 6.1
 Identities = 28/113 (24%), Positives = 53/113 (46%), Gaps = 2/113 (1%)

Query: 158 ETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVEG 217
           ++L+  G  +  + G  P    SL+    + ++++     +LP L+ +YL  N L  V  
Sbjct: 50  DSLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS 109

Query: 218 L-EDLSNLTTLHLRDNQIDTLSGFS-REMKSLQYLNLRRSKTLAFRPDQTPRG 268
           L    S++ +L L+ N+I ++ G   +   SL+ L+L  +     R    P G
Sbjct: 110 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHG 162


>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
          Length = 583

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 66/263 (25%), Positives = 102/263 (38%), Gaps = 45/263 (17%)

Query: 7   LEDSEPDQDDSEKEEDEKETEEG----EDYRKEGEEFPEEWLPTPLTEDMMKEGLSLLCK 62
           + +S P+ + +E+E   +    G    E  R  G + P      PL   +   G   L  
Sbjct: 6   VSESWPELELAERERRRELLLTGPGLEERVRAAGGQLPPRLFTLPLLHYLEVSGCGSLRA 65

Query: 63  TGNGLAHAYVKLE--VKERDLTDIYL---LRSYIHLRYVDISENHLTDLSPLNYLTHLLW 117
            G GLA    +L   V  R+     L   L     LR +D+S N L  L P         
Sbjct: 66  PGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPP--------- 116

Query: 118 LKADGNRLRSAQMNELPYLQIASFAYNQITDTEGI---SHPRLETLNLKGNSIHMVTGLD 174
               G  L  A+   LP LQ  + + N++ +         PRL++LNL GN +       
Sbjct: 117 ----GQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSF---- 168

Query: 175 PEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE-GLEDLSNLTTLHLRDNQ 233
           P +L                    LP L  L  A N L+++   +  L++L TL L +NQ
Sbjct: 169 PAELFRPGA---------------LPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQ 213

Query: 234 IDTLSGFSREMKSLQYLNLRRSK 256
           +  +     +   L+ +N R +K
Sbjct: 214 LSEIPAELADCPKLKEINFRGNK 236


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
            [Homo sapiens]
          Length = 1722

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 20/153 (13%)

Query: 103  LTDLSPLNYL-THLLW------------LKADGNRLRSAQ-MNELPYLQIASFAYNQITD 148
            LT  S  N+L +HL W            L  D N+L + + + + P +     ++N +TD
Sbjct: 946  LTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTD 1005

Query: 149  TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN---LPKLKN 204
             EG+ +   L+ L L+GN +  +  L  E L+ L  + L  N + +    +   LP L+N
Sbjct: 1006 VEGVENCGLLQILKLQGNYLSELPSL--ENLVLLRELHLDDNSISTVEAFSSYWLPLLQN 1063

Query: 205  LYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTL 237
            + ++QN L K+  L    +L  L +  N +  L
Sbjct: 1064 ITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDL 1096



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 57/233 (24%), Positives = 86/233 (36%), Gaps = 66/233 (28%)

Query: 74   LEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRS------ 127
            L ++   LT ++ L +   L+Y+D  ENH+  +   N L +L  +  + N+L S      
Sbjct: 823  LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECEN-LENLCVVLLNKNQLTSLHGLDG 881

Query: 128  ---AQMNELPYLQIASFAYN-----QITDTEGISH----------------------PRL 157
                Q  EL Y +I    Y+     ++ D  G  H                        +
Sbjct: 882  CTNIQCLELSYNKITRIGYSFFLEEKLVDNAGFCHHLGTSTSYLSLAQVWIPTGLCWSWI 941

Query: 158  ETLNLKGNS------IHMVTGLDPEKLISLHTVELRGNQLESTLGI-------------- 197
               +L  NS       H+      E L +L  + L  NQL +T G+              
Sbjct: 942  PITSLTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHN 1001

Query: 198  ---------NLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFS 241
                     N   L+ L L  N L ++  LE+L  L  LHL DN I T+  FS
Sbjct: 1002 HLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFS 1054



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 17/179 (9%)

Query: 72   VKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMN 131
            V L+     LTD+  + +   L+ + +  N+L++L  L  L  L  L  D N + + +  
Sbjct: 994  VYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAF 1053

Query: 132  E---LPYLQIASFAYNQITDTEGISH-PRLETLNLKGNSIHMVTGLDP--EKLISLHTVE 185
                LP LQ  + + N +T    + H   LE L++  N +  +       +   SLH + 
Sbjct: 1054 SSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELS 1113

Query: 186  LRGNQL-------ESTLGINLPKLKNL---YLAQNMLKKVEGLEDLSNLTTLHLRDNQI 234
            L GN L       +S L + LP L+ L    L  N   + E    L +   L L  +QI
Sbjct: 1114 LTGNPLLQETNWRDSLLKV-LPALRILNGNILNSNSESRTEEHNQLGSAGFLALCQSQI 1171


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
            [Homo sapiens]
          Length = 1336

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 42/153 (27%), Positives = 72/153 (47%), Gaps = 20/153 (13%)

Query: 103  LTDLSPLNYL-THLLW------------LKADGNRLRSAQ-MNELPYLQIASFAYNQITD 148
            LT  S  N+L +HL W            L  D N+L + + + + P +     ++N +TD
Sbjct: 946  LTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHNHLTD 1005

Query: 149  TEGISH-PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLESTLGIN---LPKLKN 204
             EG+ +   L+ L L+GN +  +  L  E L+ L  + L  N + +    +   LP L+N
Sbjct: 1006 VEGVENCGLLQILKLQGNYLSELPSL--ENLVLLRELHLDDNSISTVEAFSSYWLPLLQN 1063

Query: 205  LYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTL 237
            + ++QN L K+  L    +L  L +  N +  L
Sbjct: 1064 ITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDL 1096



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 57/233 (24%), Positives = 86/233 (36%), Gaps = 66/233 (28%)

Query: 74   LEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRS------ 127
            L ++   LT ++ L +   L+Y+D  ENH+  +   N L +L  +  + N+L S      
Sbjct: 823  LSLRRCGLTSLHSLSNCKKLKYIDAQENHIEAIECEN-LENLCVVLLNKNQLTSLHGLDG 881

Query: 128  ---AQMNELPYLQIASFAYN-----QITDTEGISH----------------------PRL 157
                Q  EL Y +I    Y+     ++ D  G  H                        +
Sbjct: 882  CTNIQCLELSYNKITRIGYSFFLEEKLVDNAGFCHHLGTSTSYLSLAQVWIPTGLCWSWI 941

Query: 158  ETLNLKGNS------IHMVTGLDPEKLISLHTVELRGNQLESTLGI-------------- 197
               +L  NS       H+      E L +L  + L  NQL +T G+              
Sbjct: 942  PITSLTKNSDCNFLISHLYWNCGLESLKNLQQLILDHNQLINTKGLCDTPTIVYLDCSHN 1001

Query: 198  ---------NLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFS 241
                     N   L+ L L  N L ++  LE+L  L  LHL DN I T+  FS
Sbjct: 1002 HLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFS 1054



 Score = 35.0 bits (79), Expect = 0.086
 Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 17/179 (9%)

Query: 72   VKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLLWLKADGNRLRSAQMN 131
            V L+     LTD+  + +   L+ + +  N+L++L  L  L  L  L  D N + + +  
Sbjct: 994  VYLDCSHNHLTDVEGVENCGLLQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAF 1053

Query: 132  E---LPYLQIASFAYNQITDTEGISH-PRLETLNLKGNSIHMVTGLDP--EKLISLHTVE 185
                LP LQ  + + N +T    + H   LE L++  N +  +       +   SLH + 
Sbjct: 1054 SSYWLPLLQNITISQNSLTKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELS 1113

Query: 186  LRGNQL-------ESTLGINLPKLKNL---YLAQNMLKKVEGLEDLSNLTTLHLRDNQI 234
            L GN L       +S L + LP L+ L    L  N   + E    L +   L L  +QI
Sbjct: 1114 LTGNPLLQETNWRDSLLKV-LPALRILNGNILNSNSESRTEEHNQLGSAGFLALCQSQI 1171


>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
          Length = 619

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 21/46 (45%), Positives = 32/46 (69%), Gaps = 1/46 (2%)

Query: 3   DEDDLEDSEPDQDDSEKEEDEKETEEGEDYRKEGEEF-PEEWLPTP 47
           +EDD ED + D+DD ++E++E+E EE ED   + E+F  +E LP P
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDP 180


>gi|22749183 leucine rich repeat and Ig domain containing 2 [Homo
           sapiens]
          Length = 606

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 46/169 (27%), Positives = 75/169 (44%), Gaps = 11/169 (6%)

Query: 132 ELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQL 191
           E   L ++      +   E IS+P LE ++L  N I  V       L +L ++ L+GN+L
Sbjct: 58  ETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRL 117

Query: 192 EST-LGI--NLPKLKNLYLAQNMLKKVEG--LEDLSNLTTLHLRDNQIDTLSG------F 240
           +   LG+   L  L  L +++N +  +     +DL NL +L + DN +  +S        
Sbjct: 118 KLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLL 177

Query: 241 SREMKSLQYLNLRRSKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLEIH 289
           S E  +L+  NL    T A    ++    H  +     MPV+A K   H
Sbjct: 178 SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFH 226



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 39/174 (22%), Positives = 71/174 (40%), Gaps = 23/174 (13%)

Query: 50  EDMMKEGLSLLCKTGNGLAH--AYVKLEVKERDLTD--IYLLRSYIHLRYVDISENHLTD 105
           E +  E  +L       L+H  + + L +K  ++ +  +Y  +   HL++++I    L D
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239

Query: 106 LSPLNYLTHLLWLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGN 165
           + P N    L  L      + +  ++ +P+L      Y             L  LNL  N
Sbjct: 240 MMPAN---SLYGLNLTSLSVTNTNLSTVPFLAFKHLVY-------------LTHLNLSYN 283

Query: 166 SIHMVTG---LDPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216
            I  +      D  +L  LH V  +   +E      L  L+ L ++QN+L+ +E
Sbjct: 284 PISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLE 337


>gi|239752518 PREDICTED: similar to leucine rich repeat containing
           50, partial [Homo sapiens]
          Length = 489

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/181 (26%), Positives = 83/181 (45%), Gaps = 19/181 (10%)

Query: 136 LQIASFAYNQITDTEGISHP-RLETLNLKGNSIHMVTGLDPEKLISLHTVELRGNQLEST 194
           L +     NQIT  E I+H   L  LNL  N +  V  L+   L SL  + LR NQ+   
Sbjct: 5   LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNG--LDSLTELNLRHNQITFV 62

Query: 195 LGI-NLPKLKNLYLAQNMLK---KVEGLEDLSNLTTLHLRDNQIDTLSGFS----REMKS 246
             + NLP L++L+L+ N +     V  L D S+L+ +    N I   S +     + M  
Sbjct: 63  RDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122

Query: 247 LQYLNLRR--------SKTLAFRPDQTPRGSHHMYDREQRMPVFAPKLEIHHNLRPRICS 298
           L+ L+++R        +  LA + ++  R SH     +++  +    +    +L+ R+ +
Sbjct: 123 LRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQRVAN 182

Query: 299 V 299
           +
Sbjct: 183 I 183



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 5/72 (6%)

Query: 180 SLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS 238
           +L  ++L GNQ+     IN L +L+ L LA+N L  V+ L  L +LT L+LR NQI    
Sbjct: 4   NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT--- 60

Query: 239 GFSREMKSLQYL 250
            F R++ +L  L
Sbjct: 61  -FVRDVDNLPCL 71


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,713,259
Number of Sequences: 37866
Number of extensions: 602056
Number of successful extensions: 10218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 315
Number of HSP's successfully gapped in prelim test: 249
Number of HSP's that attempted gapping in prelim test: 5272
Number of HSP's gapped (non-prelim): 3173
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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