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Search of human proteins with 57528101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
(557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57528101 hypothetical protein LOC728130 [Homo sapiens] 1160 0.0
gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo sap... 1117 0.0
gi|150170710 hypothetical protein LOC728118 [Homo sapiens] 1106 0.0
gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo sap... 1097 0.0
gi|239744140 PREDICTED: hypothetical protein [Homo sapiens] 1090 0.0
gi|148806874 hypothetical protein LOC54754 [Homo sapiens] 890 0.0
gi|113865921 hypothetical protein LOC441457 [Homo sapiens] 889 0.0
gi|50233787 nuclear protein in testis [Homo sapiens] 438 e-123
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 56 1e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 53 6e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 52 1e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 52 1e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 50 4e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 50 4e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 50 4e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 50 4e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 4e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 50 7e-06
gi|18959210 WIRE protein [Homo sapiens] 49 9e-06
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 49 1e-05
gi|153792074 proline rich 12 [Homo sapiens] 48 3e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 4e-05
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 47 6e-05
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 46 1e-04
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 46 1e-04
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 46 1e-04
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 46 1e-04
gi|77681565 NG5 protein [Homo sapiens] 45 2e-04
gi|150417989 cyclin K isoform 1 [Homo sapiens] 45 2e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 45 2e-04
>gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
Length = 557
Score = 1160 bits (3001), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MFQEPVYFQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPAL 60
MFQEPVYFQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPAL
Sbjct: 1 MFQEPVYFQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPAL 60
Query: 61 GPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDG 120
GPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDG
Sbjct: 61 GPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDG 120
Query: 121 CGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAA 180
CGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAA
Sbjct: 121 CGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAA 180
Query: 181 PVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLA 240
PVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLA
Sbjct: 181 PVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLA 240
Query: 241 SSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKP 300
SSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKP
Sbjct: 241 SSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKP 300
Query: 301 TMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPA 360
TMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPA
Sbjct: 301 TMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPA 360
Query: 361 TPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETK 420
TPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETK
Sbjct: 361 TPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETK 420
Query: 421 ARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQE 480
ARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQE
Sbjct: 421 ARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQE 480
Query: 481 EDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEG 540
EDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEG
Sbjct: 481 EDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEG 540
Query: 541 LTLAQGAPSDAPGTDRC 557
LTLAQGAPSDAPGTDRC
Sbjct: 541 LTLAQGAPSDAPGTDRC 557
>gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 629
Score = 1117 bits (2888), Expect = 0.0
Identities = 536/550 (97%), Positives = 541/550 (98%)
Query: 8 FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67
F+ LFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQPEGMASNGAYP LGPGVTAN
Sbjct: 80 FKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTAN 139
Query: 68 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127
PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS FPSTPLVTEQDGC PSGAG
Sbjct: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAG 199
Query: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187
ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
Query: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247
AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE SLASSQAKAP
Sbjct: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
Query: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307
PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
Query: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367
LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
Query: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427
GPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARRPPP+PHRRAETKARLPPPR
Sbjct: 440 GPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPR 499
Query: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG+VKQPQEEDWTPPD
Sbjct: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
Query: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQGA 547
PGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQ+LEQEEGLTLAQGA
Sbjct: 560 PGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQGA 619
Query: 548 PSDAPGTDRC 557
PSDAPGTDRC
Sbjct: 620 PSDAPGTDRC 629
>gi|150170710 hypothetical protein LOC728118 [Homo sapiens]
Length = 878
Score = 1106 bits (2860), Expect = 0.0
Identities = 532/538 (98%), Positives = 533/538 (99%)
Query: 8 FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67
F+ LFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN
Sbjct: 80 FKFSLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 139
Query: 68 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127
PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS PSTPLVTEQDGCGPSGAG
Sbjct: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTLPSTPLVTEQDGCGPSGAG 199
Query: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187
ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
Query: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247
AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP
Sbjct: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 319
Query: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307
PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
Query: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367
LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
Query: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427
GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR
Sbjct: 440 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 499
Query: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD
Sbjct: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 559
Query: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ 545
PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ
Sbjct: 560 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ 617
>gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 878
Score = 1097 bits (2837), Expect = 0.0
Identities = 527/538 (97%), Positives = 531/538 (98%)
Query: 8 FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67
F+ LFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQPEGMASNGAYP LGPGVTAN
Sbjct: 80 FKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTAN 139
Query: 68 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127
PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS FPSTPLVTEQDGCGPSGAG
Sbjct: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCGPSGAG 199
Query: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187
ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
Query: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247
AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE SLASSQAKAP
Sbjct: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
Query: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307
PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
Query: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367
LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
Query: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427
GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR
Sbjct: 440 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 499
Query: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG+VKQPQEEDWTPPD
Sbjct: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
Query: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ 545
PGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQ+LEQEEGLTLAQ
Sbjct: 560 PGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQ 617
>gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
Length = 878
Score = 1090 bits (2819), Expect = 0.0
Identities = 524/538 (97%), Positives = 529/538 (98%)
Query: 8 FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67
F+ LFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQPEGMASNGAYP LGPGVTAN
Sbjct: 80 FKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTAN 139
Query: 68 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127
PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS FPSTPLVTEQDGC PSGAG
Sbjct: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAG 199
Query: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187
ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
Query: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247
AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE SLASSQAKAP
Sbjct: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
Query: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307
PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
Query: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367
LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
Query: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427
GPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARRPPP+PHRRAETKARLPPPR
Sbjct: 440 GPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPR 499
Query: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG+VKQPQEEDWTPPD
Sbjct: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
Query: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQ 545
PGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQ+LEQEEGLTLAQ
Sbjct: 560 PGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQ 617
>gi|148806874 hypothetical protein LOC54754 [Homo sapiens]
Length = 756
Score = 890 bits (2300), Expect = 0.0
Identities = 438/496 (88%), Positives = 449/496 (90%), Gaps = 2/496 (0%)
Query: 51 MASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFP 110
MASNGAYP LGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA PP GPLVLS FP
Sbjct: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60
Query: 111 STPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVV 170
STPLV QDG GPSGAGASNVFVQMRTEVGPVK QAQTL+LTQ PLVWQAPG LCGGV+
Sbjct: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
Query: 171 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 230
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179
Query: 231 QGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 290
QGAHGEGSLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
Query: 291 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 350
VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRP 409
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKAPTACLPPPRPQRP TKA P
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359
Query: 410 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 469
PPRP R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE Q
Sbjct: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419
Query: 470 REEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 529
RE+G+V+QPQEED DPGLLSY DKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479
Query: 530 ALSQELEQEEGLTLAQ 545
ALSQELEQEEGLTLAQ
Sbjct: 480 ALSQELEQEEGLTLAQ 495
>gi|113865921 hypothetical protein LOC441457 [Homo sapiens]
Length = 492
Score = 889 bits (2296), Expect = 0.0
Identities = 439/507 (86%), Positives = 450/507 (88%), Gaps = 15/507 (2%)
Query: 51 MASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFP 110
MASNGAYP LGPGVT NPGTSLSVFTALPF TP+PGP H P LVTA PP GPLVLS FP
Sbjct: 1 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFP 60
Query: 111 STPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVV 170
STPLV QDG GPSGAGASNVFVQMRTEVGPVK QAQTL+LTQ PLVWQAPG LCGGV+
Sbjct: 61 STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120
Query: 171 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 230
CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNAGPWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNAGPWP 179
Query: 231 QGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 290
QGAHGEGSLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239
Query: 291 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 350
VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMA KFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWM 299
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPP 410
KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKAPTACLPPPRPQRP
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRP-------- 351
Query: 411 PRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQR 470
AETKA LPPPRP RPAETKVPEEIPPEVVQEYVDIMEELLG G TGEPE QR
Sbjct: 352 ------AETKAHLPPPRPPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 405
Query: 471 EEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLA 530
E+G+V+QPQEED DPGLLSY DKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFLA
Sbjct: 406 EKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 465
Query: 531 LSQELEQEEGLTLAQGAPSDAPGTDRC 557
LSQELEQEEGLTLAQGAPSDA GTDRC
Sbjct: 466 LSQELEQEEGLTLAQGAPSDALGTDRC 492
>gi|50233787 nuclear protein in testis [Homo sapiens]
Length = 1132
Score = 438 bits (1126), Expect = e-123
Identities = 267/504 (52%), Positives = 314/504 (62%), Gaps = 48/504 (9%)
Query: 51 MASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAP-------PGGP 103
MAS+GA GP ++ P +LS ALPF P P P P P P
Sbjct: 1 MASDGASALPGPDMSMKPSAALSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNP 60
Query: 104 LVLSNFPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPG 163
L+LS FPS+ LVT G SGAGA V V+++TE G + +Q Q +LTQT L APG
Sbjct: 61 LMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPG 120
Query: 164 ALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQ 223
CGG+ P P + A+ V ++ ++ VG +Q EG GLP P PPPP AQL PIV
Sbjct: 121 TPCGGLEGPAPPFVTASNVKTILPSKAVGVSQ--EG--PPGLP-PQPPPPVAQLVPIVPL 175
Query: 224 GNAGPWPQGAHGEGSLASSQAKAPPDDSCN-PRSVYENFRLWQHYKPLARRHLPQSPDTE 282
A P P G GEG ++ +K D + VYENFR WQ YK LARRHL QSPDTE
Sbjct: 176 EKAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTE 235
Query: 283 ALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEM 342
ALSCFLIPVLRSLAR KPTMTLEEGL A++EW+HTSNFDRMIFYEMAE+F+EFEA EEM
Sbjct: 236 ALSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEA-EEM 294
Query: 343 QIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRP 402
QIQ +Q M G Q L P +L+P GP A EV +QPVY+P KA K
Sbjct: 295 QIQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASKT------------- 341
Query: 403 VTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGA 462
R P R R+A QRP + P+EIPPE V+EYVDIME L+G L A
Sbjct: 342 -----RAPRRRQRKA-----------QRPPAPEAPKEIPPEAVKEYVDIMEWLVGTHL-A 384
Query: 463 TGEPE-KQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLS 521
TGE + KQ EEG Q QEE+ PDPGLLSY ++LCSQK FV+KVEAVIHPQFL +LLS
Sbjct: 385 TGESDGKQEEEG---QQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLS 441
Query: 522 PDPQMDFLALSQELEQEEGLTLAQ 545
P+ Q D LAL +ELEQEEGLTLAQ
Sbjct: 442 PEKQRDPLALIEELEQEEGLTLAQ 465
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/390 (21%), Positives = 131/390 (33%), Gaps = 77/390 (19%)
Query: 58 PALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTE 117
PAL + P + ALP PA PA P L P P+ P L E
Sbjct: 860 PALHNALPQQPSRPSNRAAALP-PKPARPPAVSPALTQTPLLPQPPMAQP--PQVLLEDE 916
Query: 118 QDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLL 177
+ P + +++Q +V P V +Q P PPL
Sbjct: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP----------------PPL-- 958
Query: 178 AAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEG 237
P P + Q+ Q P PPPPPP Q PP Q P P+ H +
Sbjct: 959 -PPPPHPSVQQQL------------QQQP-PPPPPPQPQPPP---QQQHQPPPRPVHLQP 1001
Query: 238 SLASSQAKAPPDDS------------------CNPRSVYENFRLWQHYK--PLARRHLPQ 277
S+ + PP P+ V ++ +H+K P + HL +
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Query: 278 SPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFE 337
+P + + +SL + P ++ + +E + S
Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPP---QQNVQPKKQELRAASVVQ--------------- 1103
Query: 338 AEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPP 397
+ + + K + + P P +P L P P PE +K PV+LP + K P
Sbjct: 1104 -PQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVI 1162
Query: 398 RPQRPVTKARRPPPRPHRRAETKARLPPPR 427
RP P + ++ E K + P +
Sbjct: 1163 RPPEQNAPPPGAPDKDKQKQEPKTPVAPKK 1192
Score = 45.1 bits (105), Expect = 2e-04
Identities = 71/288 (24%), Positives = 106/288 (36%), Gaps = 71/288 (24%)
Query: 172 PPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGL------PLPP--PPPPAAQLPPIVSQ 223
PPP + A VPV+ Q+ G G ++Q + LPP P PP PP ++Q
Sbjct: 797 PPPFI---ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQ 853
Query: 224 GNAGPWPQGAHG----EGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSP 279
+A P H + S S++A A P P +V PL LPQ P
Sbjct: 854 -HAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALT----QTPL----LPQPP 904
Query: 280 DTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAE 339
+ P + LE+ E M +
Sbjct: 905 MAQP----------------PQVLLED-------EEPPAPPLTSM--------------Q 927
Query: 340 EEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRP 399
++ +Q+ Q ++ P L P + +P PP P V + P P PPP+P
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPP-PPLPPPPHPSVQQQLQQQPPPP----PPPQP 982
Query: 400 QRPVTKARRPPPRPHRRAETK-----ARLPPPRPQRPAETKVPEEIPP 442
Q P + +PPPRP + + PPP+ Q+P ++ PP
Sbjct: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 395 PPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAE-TKVPEEIPPEVVQEYVDIME 453
P P PQ+P ++PPP P + + + PPP P P + + PP + V ++E
Sbjct: 750 PAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809
Query: 454 ELLGPSL 460
L S+
Sbjct: 810 PQLPGSV 816
Score = 34.3 bits (77), Expect = 0.31
Identities = 29/113 (25%), Positives = 44/113 (38%), Gaps = 14/113 (12%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVK----------QPVYLPSKAGPKAPTACLPPPRPQRP 402
P PPP P+ +P PAP+ V+ QPV KA T P P
Sbjct: 246 PLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT---TPTTIDP 302
Query: 403 VTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEEL 455
+ + PP P + + R RP +P + VP+ ++ + E+L
Sbjct: 303 IHEPPSLPPEP-KTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 5/89 (5%)
Query: 358 PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQR---PVTKARRPPPRPH 414
P TP L + P V QP+ P P+ P P+P + P+ A P +
Sbjct: 226 PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTK 285
Query: 415 RRAETKARLPPPRPQRPAETKVPEEIPPE 443
+ + KA P P P +PPE
Sbjct: 286 KGVKRKADTTTPTTIDPIHE--PPSLPPE 312
Score = 32.0 bits (71), Expect = 1.5
Identities = 49/206 (23%), Positives = 79/206 (38%), Gaps = 32/206 (15%)
Query: 345 QKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQ------PVYLPSKAGPKAPTACLPPP- 397
Q+ Q P PP P+ +P PP P+ +Q P +P +A P ++ PPP
Sbjct: 744 QQMQQAPAPVPQQPPPPPQ-QPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSS--PPPF 800
Query: 398 -RPQRPVTKARRP----PPRPHRRAETKARLPPPRPQRPAETKVPEE--IPPEVVQEYV- 449
Q PV + + P P H T+ L P+P+ P P E PP + Q V
Sbjct: 801 IATQVPVLEPQLPGSVFDPIGH---FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVV 857
Query: 450 -------DIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKD 502
+ ++ PS A P K V + P P + L ++
Sbjct: 858 SPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917
Query: 503 ----FVTKVEAVIHPQFLEELLSPDP 524
+T ++ ++ Q L+++ P P
Sbjct: 918 PPAPPLTSMQMQLYLQQLQKVQPPTP 943
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/134 (33%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 358 PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPP-----R 412
PPA PR PRG PA P P+ P AP A P R R A PP +
Sbjct: 108 PPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166
Query: 413 PHRRAETKARL--PPPRPQRP---AETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPE 467
P RA+ A L PPP P P A P PP V E L P P+
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA----AREPPLPPPPQPPAPPQ 222
Query: 468 KQREEGEVKQPQEE 481
+Q+ QP E
Sbjct: 223 QQQPPPPQPQPPPE 236
Score = 43.1 bits (100), Expect = 7e-04
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 17/129 (13%)
Query: 358 PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQR---PVTKARRPP--PR 412
PP+ +P GP A P+ P A P AP A PP P+R P AR PP P
Sbjct: 159 PPSPGPAQP-GPRAQRAA--PLAAPPPA-PAAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214
Query: 413 PHRRAETKARLPPP-RPQRPAE---TKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 468
P A + + PPP +PQ P E + P ++E V LG S GA G +
Sbjct: 215 PQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVV----RYLGGSGGAGGRLTR 270
Query: 469 QREEGEVKQ 477
R +G +++
Sbjct: 271 GRVQGLLEE 279
Score = 41.2 bits (95), Expect = 0.003
Identities = 39/136 (28%), Positives = 45/136 (33%), Gaps = 12/136 (8%)
Query: 363 RLEP--RGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETK 420
R++P RG P + P P+ A AP PP P PV A P R R A
Sbjct: 98 RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA--APARAPRAAAAA 155
Query: 421 ARLPP--------PRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
A PP PR QR A P P P A EP
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPP 215
Query: 473 GEVKQPQEEDWTPPDP 488
PQ++ PP P
Sbjct: 216 QPPAPPQQQQPPPPQP 231
Score = 35.4 bits (80), Expect = 0.14
Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 11/51 (21%)
Query: 352 GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRP 402
GP+ PPPA EP PP P QP P + P PPP+PQ P
Sbjct: 195 GPRRAPPPAVAAREPPLPPPP----QPPAPPQQQQP-------PPPQPQPP 234
Score = 33.9 bits (76), Expect = 0.40
Identities = 50/193 (25%), Positives = 58/193 (30%), Gaps = 49/193 (25%)
Query: 55 GAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPL 114
GA P P A G + A P TPAP P P V A AP P + + P
Sbjct: 105 GATPPAPP--RAPRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAP- 159
Query: 115 VTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPP 174
PS A + GP A P A G PPP
Sbjct: 160 --------PSPGPA---------QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202
Query: 175 LLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAH 234
+ A P PLPPPP P A P Q P PQ
Sbjct: 203 AVAAREP------------------------PLPPPPQPPA---PPQQQQPPPPQPQPPP 235
Query: 235 GEGSLASSQAKAP 247
G++ + A P
Sbjct: 236 EGGAVRAGGAARP 248
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/241 (22%), Positives = 94/241 (39%), Gaps = 46/241 (19%)
Query: 270 LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEM 329
++++ +PQ P + +I V K + EE ++ A S+ + + +
Sbjct: 9209 VSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFA-------SHTEEEVSVTV 9261
Query: 330 AEKFLEFEAEEEMQIQKSQWMKGP-------------QCLPPPATPRLEPRGPPAPEVVK 376
E E EE++ + S+ ++ P + P P ++EP P PEV K
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321
Query: 377 QPVYLPSKAGPKAPTACLPPPR----PQRPVTKARRPPPRPHRRAETKARLPPPRPQRPA 432
+PV K P PP+ P++PV + + P P ++ A++P +
Sbjct: 9322 KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVT 9381
Query: 433 ETKVP-----EEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
E K+ EE PP V E P+K+ E P++E+ PP
Sbjct: 9382 EEKITIVTQREESPPPAVPEI-----------------PKKKVPEERKPVPRKEEEVPPP 9424
Query: 488 P 488
P
Sbjct: 9425 P 9425
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 356 LPPPATPRLEPRGPPAPEVVKQPVYLPSKAGP-KAPTACLPPPR-----PQRPVTKARRP 409
+P P ++E PEV K+PV P K P AP PP P++ + + ++P
Sbjct: 10017 VPVPVPKKVEAPPAKVPEVPKKPV--PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKP 10074
Query: 410 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 469
P P K PPP+ + E P +P + QE + EE + P E E+
Sbjct: 10075 TPVPK-----KVEAPPPKVPKKRE---PVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEV 10126
Query: 470 REEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVI 511
E E P+EE+ P + + +++ ++++V + E +
Sbjct: 10127 LPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168
Score = 47.4 bits (111), Expect = 4e-05
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 11/173 (6%)
Query: 339 EEEMQIQKSQWMKGPQCLPP--PATPRLEPRGP-PAPEVVKQPVYLPSKAGPKAPTACLP 395
EE++ + + ++ P P P P E + P PAP+ V+ P P+K P+ P +P
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAP---PAKV-PEVPKKLIP 10069
Query: 396 PPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEEL 455
+ PV K PP + +P PQ E EEI PE +E + EE+
Sbjct: 10070 EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQE-EEVLFEEEIVPE--EEVLPEEEEV 10126
Query: 456 LGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVE 508
L E E+ E E P+EE+ PP+ + ++ +++ + +V+
Sbjct: 10127 LPEEEEVLPEEEEVLPEEEEIPPEEEE-VPPEEEYVPEEEEFVPEEEVLPEVK 10178
Score = 47.4 bits (111), Expect = 4e-05
Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 18/146 (12%)
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAP------TACLPPPRPQRPV 403
K P+ +PP +P PP PEV + P +P K P AP T P P+ V
Sbjct: 10565 KVPEAIPP------KPESPP-PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVV 10617
Query: 404 TKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGAT 463
+ + P P P + ++P E KVPE IPP+ ++ EE P A
Sbjct: 10618 PEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE---PEEVAL 10674
Query: 464 GEPEKQ-REEGEVKQPQEEDWTPPDP 488
EP + EE E P + P P
Sbjct: 10675 EEPPAEVVEEPEPAAPPQVTVPPKKP 10700
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 20/188 (10%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PPPA P+ P E K PV +P K +AP A +P P++PV + + P P P
Sbjct: 9999 PPPAKVPEVPKKPVPEE--KVPVPVPKKV--EAPPAKVPEV-PKKPVPEKKVPVPAPK-- 10051
Query: 417 AETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVK 476
K PP + + +PEE P V + V+ + P +E EV
Sbjct: 10052 ---KVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL 10108
Query: 477 QPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPD-----PQMDFLAL 531
+E P+ +L +++ +++ V E + P+ EE + P+ P+ +++
Sbjct: 10109 FEEE---IVPEEEVLPEEEEVLPEEEEVLPEEEEVLPE--EEEIPPEEEEVPPEEEYVPE 10163
Query: 532 SQELEQEE 539
+E EE
Sbjct: 10164 EEEFVPEE 10171
Score = 45.1 bits (105), Expect = 2e-04
Identities = 67/238 (28%), Positives = 99/238 (41%), Gaps = 64/238 (26%)
Query: 305 EEGLWRAMREW----QHTSNFDRMIFYEMAEKFLE-FEAEEEMQIQKSQWM-KGPQC--- 355
EEG + + E+ QH + + E + +E FEAEE +K + KGP+
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRV--EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448
Query: 356 -LPP--PATPRLEPRGPPA--PEV-----VKQPVYLPSKAGPKAPTACLP---PPR---- 398
+PP P T + + PPA PEV V++ V +P + P+ P +P PP+
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE--PRVPPTKVPEVLPPKEVVP 10506
Query: 399 ----PQRPVTKARRPPPRPHRRA-----ETKARLPPPR---------PQRPA----ETKV 436
P P K PPP+ E K +PPP+ P+ P E KV
Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566
Query: 437 PEEIPP-------EVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487
PE IPP EV + +++ E P+ P K+ E VK P+ P+
Sbjct: 10567 PEAIPPKPESPPPEVPEAPKEVVPEKKVPA-----APPKKPEVTPVKVPEAPKEVVPE 10619
Score = 44.7 bits (104), Expect = 2e-04
Identities = 43/160 (26%), Positives = 70/160 (43%), Gaps = 13/160 (8%)
Query: 327 YEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR---GPPAPEVVKQPVYLPS 383
YE+ E+ E+ EE++ I K + P T R E + P P +++P P
Sbjct: 9525 YEVMEEPEEYVVEEKLHIIS----KRVEAEPAEVTERQEKKIVLKPKIPAKIEEP---PP 9577
Query: 384 KAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPE 443
P+AP +P + PV K + PP P E K +P + P K+ E +P +
Sbjct: 9578 AKVPEAPKKIVPEKKVPAPVPKKEKVPP-PKVPEEPKKPVPEKKVP-PKVIKMEEPLPAK 9635
Query: 444 VVQEYVDI-MEELLGPSLGATGEPEKQREEGEVKQPQEED 482
V + ++ I EE + ++ P K R E K+ E+
Sbjct: 9636 VTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEE 9675
Score = 43.9 bits (102), Expect = 4e-04
Identities = 54/230 (23%), Positives = 99/230 (43%), Gaps = 49/230 (21%)
Query: 295 LARRKPTMTLEEGLWRAMRE--WQHTSNFDRMIF--YEMAEKFLEFEAEEEMQIQKSQWM 350
+ ++ TLEE RE ++ +D F YE E++ ++E EE + ++ +
Sbjct: 9723 MEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYE-- 9780
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRP 409
+ + + P P +P K P P+ PV TK + P
Sbjct: 9781 EHEEYITEPEKP------------------IPVK------------PVPEEPVPTKPKAP 9810
Query: 410 PPRPHRRA--ETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDI------MEELLGPSLG 461
P + ++A E K +P P+ +P KVPEE P +V +E + I E++ P+
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE-PKKVFEEKIRISITKREKEQVTEPAAK 9869
Query: 462 ATGEPEKQREEGEVKQPQEEDWTP---PDPGLLSYTDKLCSQKDFVTKVE 508
+P++ E +V P++E P P+ +++ +++ VT VE
Sbjct: 9870 VPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVE 9919
Score = 42.7 bits (99), Expect = 9e-04
Identities = 47/188 (25%), Positives = 86/188 (45%), Gaps = 17/188 (9%)
Query: 360 ATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAET 419
A P P P PE K PV +P K P P A +P P++PV + + P P P +
Sbjct: 9973 APPAKVPEVPKKPEE-KVPVLIPKKEKP--PPAKVPEV-PKKPVPEEKVPVPVPKKVEAP 10028
Query: 420 KARLPPPRPQRPAETKVPEEIPPEV---VQEYVDIMEELLGPSLGATGEPEKQREEGEVK 476
A++P + E KVP P +V + ++ ++L+ T P+K E K
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV-EAPPPK 10087
Query: 477 QPQEEDWTP-----PDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 531
P++ + P P + + +++ +++ + + E V+ + EE+L + ++ L
Sbjct: 10088 VPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE--EEVLPEEEEV--LPE 10143
Query: 532 SQELEQEE 539
+E+ EE
Sbjct: 10144 EEEIPPEE 10151
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 17/151 (11%)
Query: 339 EEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAPTACLPPP 397
EE +I + + + P P EP PP P V ++P +P K P PPP
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP-PAVPEEPKKIIPEKKVPVIKKPEAPPP 10863
Query: 398 RPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEE------IPPEVVQEYVDI 451
+ P +P +P PPP P P + V E+ IP + V E +
Sbjct: 10864 KEPEPEKVIEKPKLKPR---------PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914
Query: 452 MEELLGPSLGATGEPEKQREEGEVKQPQEED 482
E++ L G +K R+ ++P+ ++
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/165 (27%), Positives = 72/165 (43%), Gaps = 25/165 (15%)
Query: 322 DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP-APEVVKQPVY 380
++ I E+ L E EE + + + P+ PP+ +E PP PEV+K
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE--EPPSIEEVEEVAPPRVPEVIK---- 10274
Query: 381 LPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEI 440
KA P+APT PV K PP + + ++P P ++ A E+
Sbjct: 10275 ---KAVPEAPT----------PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEV 10321
Query: 441 PPEVVQEYVDI-MEELLGPSLGATGEPEKQ----REEGEVKQPQE 480
P +V ++ V + +E + P+ G T EK R+E VK+ E
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLE 10366
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/127 (29%), Positives = 48/127 (37%), Gaps = 18/127 (14%)
Query: 369 PPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-----TKARRPPPRPHRRAETKAR- 422
P E +P L P P PPP+P V TK R P P + E K
Sbjct: 10957 PEEEEPKVEPKKLEKVKKPAVPEP--PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 11014
Query: 423 -LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEE 481
LP P P+ E +V PP V E I + P +G ++ E K P+EE
Sbjct: 11015 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVG---------KKAEAKAPKEE 11065
Query: 482 DWTPPDP 488
P P
Sbjct: 11066 AAKPKGP 11072
Score = 41.2 bits (95), Expect = 0.003
Identities = 73/328 (22%), Positives = 118/328 (35%), Gaps = 63/328 (19%)
Query: 210 PPPPAAQLP---------PIVSQGNAGPWPQGAHGEGSLASSQAKA--PPDDSCNPRSVY 258
PPP + P P++ + A P P+ E + + K PP P+
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPP-PKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893
Query: 259 ENFRLWQHYKPLARRHLP---QSPDTEALSCFLIP-----VLRSLARRKPTMTLEEGLWR 310
+ +++Q K + ++ +P Q P+ L+ +P V + L RKP E L
Sbjct: 10894 KE-KIFQ-LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKS 10951
Query: 311 AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP 370
+R+ E E +++ +K + +K P PP +E P
Sbjct: 10952 VLRKRPE-------------------EEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992
Query: 371 APEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQR 430
++ + P+K P LP P P+P AE K PPP
Sbjct: 10993 TVTKRERKIPEPTKVPEIKPAIPLPAPE------------PKPKPEAEVKTIKPPPVEPE 11040
Query: 431 PAETKVPEEIPPEVVQEYVDI---MEELLGPSLGATGEPEKQREEGEVK----QPQEEDW 483
P P +P VV + + EE P G P+K E + +P
Sbjct: 11041 PTPIAAPVTVP--VVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGE 11098
Query: 484 TPPDPGLLSYTDKLCSQKDFVTKVEAVI 511
PPD +Y K K FV +++ +I
Sbjct: 11099 KPPDEAPFTYQLKAVPLK-FVKEIKDII 11125
Score = 37.7 bits (86), Expect = 0.028
Identities = 47/198 (23%), Positives = 75/198 (37%), Gaps = 33/198 (16%)
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQP------------VYLPSKAGPKAPTACLPPPR 398
K P+ +PP +P PP PEV ++P V P A P P +PP +
Sbjct: 10649 KVPEAIPP------KPESPP-PEVFEEPEEVALEEPPAEVVEEPEPAAP--PQVTVPPKK 10699
Query: 399 P----QRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEE-------IPPEVVQE 447
P + P A++P P + E + P + K PE +P EVV E
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE 10759
Query: 448 -YVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTK 506
V + ++ P P+K E + P E P P + +++ +++ +
Sbjct: 10760 KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPE 10819
Query: 507 VEAVIHPQFLEELLSPDP 524
E + EE P P
Sbjct: 10820 EEKPVPVAEEEEPEVPPP 10837
Score = 36.6 bits (83), Expect = 0.062
Identities = 43/154 (27%), Positives = 63/154 (40%), Gaps = 29/154 (18%)
Query: 356 LPPPATPRLEPRGPPA-----PEVVKQPVYLPSKAGPK------------------APTA 392
+PPP P EP+ P P+V+K LP+K + AP
Sbjct: 9603 VPPPKVPE-EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPK 9661
Query: 393 CLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIP---PEVVQEYV 449
P P+R V + + +P R E A++ R + E KV E P P+ ++E V
Sbjct: 9662 ARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKE-V 9720
Query: 450 DIMEELLGPSLGATGEPEKQREEGEVKQPQEEDW 483
IMEE QREE E ++ +E D+
Sbjct: 9721 TIMEEKERAYTLEEEAVSVQREE-EYEEYEEYDY 9753
Score = 36.6 bits (83), Expect = 0.062
Identities = 37/162 (22%), Positives = 66/162 (40%), Gaps = 19/162 (11%)
Query: 396 PPRPQRPVTKARRPPPRPHRRAETKARLPP-------------PRPQRPAETKVPEEIPP 442
P P++PV + ++P P P ++ A++P P+ ++P KVP E+P
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVP-EVPK 10009
Query: 443 EVVQEY---VDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCS 499
+ V E V + +++ P P+K E +V P + P + KL
Sbjct: 10010 KPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIP 10069
Query: 500 QKDFVTKVEAVIH--PQFLEELLSPDPQMDFLALSQELEQEE 539
++ T V + P + + P P L +E+ EE
Sbjct: 10070 EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEE 10111
Score = 35.8 bits (81), Expect = 0.11
Identities = 38/138 (27%), Positives = 53/138 (38%), Gaps = 41/138 (29%)
Query: 353 PQCLPPPATPRLEPRGPP-APEVVKQPVY-----LPSKAGPKAPTACLP----------- 395
P+ P P+ EP PP PEV K+PV +P +AP A +P
Sbjct: 9325 PEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEK 9384
Query: 396 ---------------PPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEI 440
P P++ V + R+P PR K PP P+ PA K P +
Sbjct: 9385 ITIVTQREESPPPAVPEIPKKKVPEERKPVPR-------KEEEVPPPPKVPALPKKP--V 9435
Query: 441 PPEVVQEYVDIMEELLGP 458
P E V V + ++ P
Sbjct: 9436 PEEKVAVPVPVAKKAPPP 9453
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/119 (30%), Positives = 52/119 (43%), Gaps = 16/119 (13%)
Query: 337 EAEEEMQIQKSQWMKGPQCLP--PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACL 394
E EEE ++ +++ + +P P P + PR P E K+PV +P K +AP A +
Sbjct: 9924 EEEEEYIHEEEEFITEEEVVPVIPVKVPEV-PRKPVPEE--KKPVPVPKKK--EAPPAKV 9978
Query: 395 P--PPRPQRPVT----KARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P P +P+ V K +PPP K P P + P E PP V E
Sbjct: 9979 PEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKK---PVPEEKVPVPVPKKVEAPPAKVPE 10034
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 27/138 (19%)
Query: 326 FYEMAEKFLEFEAE--------EEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQ 377
+YE E + E E E E +Q+QK + + + P P E + PP P+V+K+
Sbjct: 9126 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVP--EKKAPPPPKVIKK 9183
Query: 378 PVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQR-PAETKV 436
PV K + VTK E ++ P +P R P + +V
Sbjct: 9184 PVI------EKIEKTSRRMEEEKVQVTKV----------PEVSKKIVPQKPSRTPVQEEV 9227
Query: 437 PEEIPPEVVQEYVDIMEE 454
E P V + + I EE
Sbjct: 9228 IEVKVPAVHTKKMVISEE 9245
Score = 30.8 bits (68), Expect = 3.4
Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 15/90 (16%)
Query: 338 AEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPP 397
A EM I + + P PP P+ + R P P + KA A P
Sbjct: 235 ATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSI-----------AAKAQLARQQSP 283
Query: 398 RPQR----PVTKARRPPPRPHRRAETKARL 423
P R PV R P P P R AR+
Sbjct: 284 SPIRHSPSPVRHVRAPTPSPVRSVSPAARI 313
Score = 30.0 bits (66), Expect = 5.8
Identities = 33/114 (28%), Positives = 45/114 (39%), Gaps = 13/114 (11%)
Query: 362 PRLEPRGPPAPEV---VKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAE 418
PR E PP P+V K+PV A P PPPR + + +R
Sbjct: 9415 PRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPR-----AEVSKKTVVEEKRFV 9469
Query: 419 TKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
+ +L PQR T+ E+ E Y EE G S+ E E++ EE
Sbjct: 9470 AEEKLSFAVPQRVEVTR--HEVSAEEEWSY---SEEEEGVSISVYREEEREEEE 9518
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 52.0 bits (123), Expect = 1e-06
Identities = 95/371 (25%), Positives = 135/371 (36%), Gaps = 63/371 (16%)
Query: 206 PLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAPPD---DSCNPRSVYENFR 262
PL PPPPP PP+ S P P A E Q ++PP +C+ +
Sbjct: 427 PLCPPPPPPVSPPPLPS-----PPPPPAQEE------QEESPPPVVPATCSRKRGRPPLT 475
Query: 263 LWQHYKPLARRHLPQ--SPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSN 320
Q + A R P+ SP T S P T R ++
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535
Query: 321 FDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPAT--PRLEPRGPPAPEVVKQP 378
R+I + +F++ + + +++ S ++ P PP P P P AP P
Sbjct: 536 SSRVI--KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593
Query: 379 VYLPSKAGP---------KAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRP- 428
V LP K + T LPPP P P PPP P PPP P
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPP------PPPAPS---------PPPAPA 638
Query: 429 ---QRPAETKVPEEIPPEVVQEYVDIMEELL-GPSLGATGEPEKQREEGEVKQPQEEDWT 484
+RP + P+ P E ++ I E +L P LGA PE + P ++
Sbjct: 639 TSSRRPLLLRAPQFTPSEA---HLKIYESVLTPPPLGAPEAPEPE------PPPADDSPA 689
Query: 485 PPDPGLLSYTDKLCSQK---DFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGL 541
P+P + T+ L + T V+A + P LS PQ L Q L+ +
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG-APALSNGPQTQ-AQLLQPLQALQTQ 747
Query: 542 TLAQGAPSDAP 552
L Q P P
Sbjct: 748 LLPQALPPPQP 758
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 40/161 (24%)
Query: 328 EMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGP 387
E EK AEE M + + K P PPP TP PP P PS + P
Sbjct: 377 EGEEKEERAVAEEMMPAAEKEEAKLP---PPPLTPPAPSPPPPLPP--------PSTSPP 425
Query: 388 KAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P C PPP P PPP P PPP P + + EE PP VV
Sbjct: 426 --PPLCPPPPPPV-------SPPPLPS---------PPPPPAQEEQ----EESPPPVV-- 461
Query: 448 YVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDP 488
G QR E E + E +PP P
Sbjct: 462 -----PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497
Score = 38.9 bits (89), Expect = 0.013
Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 33/122 (27%)
Query: 354 QCLPPPATPRLEPRGPPAPEV-----VKQPVYLPSKA-----------GPKAPTACL--- 394
Q L PP P PPAP +K P Y PS+ P +P++
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898
Query: 395 ----------PPPRPQRPVTKARRPPP----RPHRRAETKARLPPPRPQRPAETKVPEEI 440
PP R +RP A RPPP P + + R+PPP A T E+
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
Query: 441 PP 442
P
Sbjct: 1959 AP 1960
Score = 37.7 bits (86), Expect = 0.028
Identities = 52/208 (25%), Positives = 74/208 (35%), Gaps = 56/208 (26%)
Query: 45 SAQPEGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPL 104
S P +NG+ P+ G+TA+P F LP A G +++ G P P
Sbjct: 2135 SLPPAPPLANGSQPS--QGLTASPADPTRTFAWLP-------GAPGVRVLSLGPAPEPPK 2185
Query: 105 VLSNFPSTPLVTEQDGCGPSGAGASNVFVQMRTE----VGPVKAAQAQTLVLTQTPLVWQ 160
P+T + + G VFV+M E PVK + P W
Sbjct: 2186 -----PATSKIILVNKLG-------QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW- 2232
Query: 161 APGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPI 220
PP LL PVV G+ P PPPP L +
Sbjct: 2233 ---------TLPPGPLLGVLPVV--------------------GVVRPAPPPPPPPLTLV 2263
Query: 221 VSQGNAGPWPQGAHGEGSLASSQAKAPP 248
+S G A P P+ A +++ ++PP
Sbjct: 2264 LSSGPASP-PRQAIRVKRVSTFSGRSPP 2290
Score = 36.6 bits (83), Expect = 0.062
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 24/133 (18%)
Query: 363 RLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRP---QRPVTKARRPPPRPHRRAET 419
++ G P P VKQP LP P APT+ PP P PV RP P
Sbjct: 2203 KMAGEGEPVPPPVKQPP-LPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPP------- 2254
Query: 420 KARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQR--EEGEVKQ 477
PPP P + P P + ++ V + G S A + R E+GE +
Sbjct: 2255 ----PPPPPLTLVLSSGPASPPRQAIR--VKRVSTFSGRSPPAPPPYKAPRLDEDGEASE 2308
Query: 478 PQEEDWTPPDPGL 490
TP PGL
Sbjct: 2309 D-----TPQVPGL 2316
Score = 30.4 bits (67), Expect = 4.5
Identities = 28/103 (27%), Positives = 38/103 (36%), Gaps = 25/103 (24%)
Query: 351 KGPQCLPPPATPRLEP-RGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRP 409
+ P+ P P PR G P EVV P GP+ + L +R V + RP
Sbjct: 1034 ESPEASPGPPGPRRGAGAGGPREEVVAHP-------GPEEQDSLLQRKSARRCVKQ--RP 1084
Query: 410 ---------------PPRPHRRAETKARLPPPRPQRPAETKVP 437
PP P RR + LP P P+ + + P
Sbjct: 1085 SYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKP 1127
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T P
Sbjct: 434 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486
Query: 413 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 471
P + T +L P P++PA T PEE+ P +E E P+ P +E
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545
Query: 472 EGEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 546 PAPTTPKEPAPTTPKEP 562
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/135 (27%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPH 414
P P T + P P P+P K+P P+ APT P+ P T P P
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 456
Query: 415 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P P+ PA T P+E P ++ E L P+ P E
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515
Query: 474 EVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 516 PTTPEEPTPTTPEEP 530
Score = 42.7 bits (99), Expect = 9e-04
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 11/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T + P
Sbjct: 442 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
P + A T P P PEE P +E + P+ P +E
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554
Query: 473 GEVKQPQEEDWTPPD 487
+ TP +
Sbjct: 555 APTTPKEPAPTTPKE 569
Score = 39.3 bits (90), Expect = 0.010
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 30/149 (20%)
Query: 357 PPPATPR----LEPRGPP------APEVVKQPVYLPSKAGPKAPTACLP-------PPRP 399
P P TP+ P+ P AP K+P +K+ P P P P P
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 275
Query: 400 QRPV-TKARRPPPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLG 457
+ P T + P P + A T + P P P++PA T P+E P +E
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE---------- 324
Query: 458 PSLGATGEPEKQREEGEVKQPQEEDWTPP 486
P+ EP +E P+E T P
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 6/137 (4%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPV-YLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P T P P PAP K+P P + P P P + T + P P
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
+ A T + P P + A T P+E P +E + P+ P +E
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPT-TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Query: 474 EV--KQPQEEDWTPPDP 488
K+P P P
Sbjct: 452 PTTPKEPAPTTTKKPAP 468
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 13/90 (14%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYL----PSKAGPKAPTACLPPPRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ PK P P P P A P
Sbjct: 301 PAPTTPK-----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA---PTA 352
Query: 413 PHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P + A T + P P P+ PA T E P
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 382
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 357 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAPTACLP-PPRPQRPVTKARRPPP 411
P P TP+ EP PAP K P + P P P P+ P T P
Sbjct: 270 PAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328
Query: 412 RPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P A T P P+ PA T P++ P +E
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE 363
Score = 38.1 bits (87), Expect = 0.021
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)
Query: 357 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPK--APTACLPPPRPQRPVTKARRP 409
P P TP+ P+G AP +K+P P K PK APT P T +
Sbjct: 631 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPA 685
Query: 410 PPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 468
P P A T + P P P++PA T PE PP + V P+ E
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 742
Query: 469 QREEGEVKQPQEEDWTPPDPGL 490
E P+ + +P +PG+
Sbjct: 743 TPELSAEPTPKALENSPKEPGV 764
Score = 37.7 bits (86), Expect = 0.028
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 12/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR-PQRPV-TKARRPPPR-P 413
P P TP+ PAP K+P P+ APT P P P+ P T ++P P P
Sbjct: 309 PAPTTPK-----EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P + P+E P + +E + + K+
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421
Query: 474 EVKQPQEEDWTPPDP 488
K+P TP +P
Sbjct: 422 TTKEPAPT--TPKEP 434
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPR 412
P P TP+ P P PAP K+P K T P P+ P T + P
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
A T + P P+ P+ T +E P +E + P+ P +E
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 473 GEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 459 APTTTKKPAPTTPKEP 474
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 19/102 (18%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLP-------PPRPQRPVTKAR 407
P P T + P P PAP K+P P P P P P+ P +
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAPTTPKEPTPTTPKEPAPTTK 338
Query: 408 RP-PPRPHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQE 447
P P P A T + P P P+ PA T P+E P +E
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 379
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 9/84 (10%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P TP+ P P PAP K+P P+ APT P+ P T P
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTT----PKETAPTTPKGTAPTTL 583
Query: 414 HRRAETKARLPPPRPQRPAETKVP 437
A T + P P+ P TK P
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEP 607
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)
Query: 362 PRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPRPHRRAETK 420
P L P P K+P K P T P P+ P T + P P A T
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266
Query: 421 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQ 479
+ P P P+ PA T E P E P+ P +E +
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 324
Query: 480 EEDWTPPDP 488
TP +P
Sbjct: 325 PTPTTPKEP 333
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 7/91 (7%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP-PRPQRPVTKARRPPP 411
P+ L P +L P P P P+ P+ PT P P P P A P
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 544
Query: 412 RPHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P A T + P P P+ PA T E P
Sbjct: 545 EP---APTTPKEPAPTTPKEPAPTTPKETAP 572
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T P
Sbjct: 475 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527
Query: 413 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 471
P + T +L P P++PA T PEE+ P +E E P+ P +E
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586
Query: 472 EGEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 587 PAPTTPKEPAPTTPKEP 603
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/135 (27%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPH 414
P P T + P P P+P K+P P+ APT P+ P T P P
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 497
Query: 415 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P P+ PA T P+E P ++ E L P+ P E
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556
Query: 474 EVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 557 PTTPEEPTPTTPEEP 571
Score = 42.7 bits (99), Expect = 9e-04
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 11/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T + P
Sbjct: 483 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
P + A T P P PEE P +E + P+ P +E
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595
Query: 473 GEVKQPQEEDWTPPD 487
+ TP +
Sbjct: 596 APTTPKEPAPTTPKE 610
Score = 39.3 bits (90), Expect = 0.010
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 30/149 (20%)
Query: 357 PPPATPR----LEPRGPP------APEVVKQPVYLPSKAGPKAPTACLP-------PPRP 399
P P TP+ P+ P AP K+P +K+ P P P P P
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 316
Query: 400 QRPV-TKARRPPPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLG 457
+ P T + P P + A T + P P P++PA T P+E P +E
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE---------- 365
Query: 458 PSLGATGEPEKQREEGEVKQPQEEDWTPP 486
P+ EP +E P+E T P
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 6/137 (4%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPV-YLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P T P P PAP K+P P + P P P + T + P P
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
+ A T + P P + A T P+E P +E + P+ P +E
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPT-TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Query: 474 EV--KQPQEEDWTPPDP 488
K+P P P
Sbjct: 493 PTTPKEPAPTTTKKPAP 509
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 13/90 (14%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYL----PSKAGPKAPTACLPPPRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ PK P P P P A P
Sbjct: 342 PAPTTPK-----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA---PTA 393
Query: 413 PHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P + A T + P P P+ PA T E P
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 423
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 357 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAPTACLP-PPRPQRPVTKARRPPP 411
P P TP+ EP PAP K P + P P P P+ P T P
Sbjct: 311 PAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 369
Query: 412 RPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P A T P P+ PA T P++ P +E
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE 404
Score = 38.1 bits (87), Expect = 0.021
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)
Query: 357 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPK--APTACLPPPRPQRPVTKARRP 409
P P TP+ P+G AP +K+P P K PK APT P T +
Sbjct: 672 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPA 726
Query: 410 PPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 468
P P A T + P P P++PA T PE PP + V P+ E
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 783
Query: 469 QREEGEVKQPQEEDWTPPDPGL 490
E P+ + +P +PG+
Sbjct: 784 TPELSAEPTPKALENSPKEPGV 805
Score = 37.7 bits (86), Expect = 0.028
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 12/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR-PQRPV-TKARRPPPR-P 413
P P TP+ PAP K+P P+ APT P P P+ P T ++P P P
Sbjct: 350 PAPTTPK-----EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P + P+E P + +E + + K+
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462
Query: 474 EVKQPQEEDWTPPDP 488
K+P TP +P
Sbjct: 463 TTKEPAPT--TPKEP 475
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPR 412
P P TP+ P P PAP K+P K T P P+ P T + P
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
A T + P P+ P+ T +E P +E + P+ P +E
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 473 GEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 500 APTTTKKPAPTTPKEP 515
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 19/102 (18%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLP-------PPRPQRPVTKAR 407
P P T + P P PAP K+P P P P P P+ P +
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAPTTPKEPTPTTPKEPAPTTK 379
Query: 408 RP-PPRPHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQE 447
P P P A T + P P P+ PA T P+E P +E
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 420
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 9/84 (10%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P TP+ P P PAP K+P P+ APT P+ P T P
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTT----PKETAPTTPKGTAPTTL 624
Query: 414 HRRAETKARLPPPRPQRPAETKVP 437
A T + P P+ P TK P
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEP 648
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)
Query: 362 PRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPRPHRRAETK 420
P L P P K+P K P T P P+ P T + P P A T
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307
Query: 421 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQ 479
+ P P P+ PA T E P E P+ P +E +
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 365
Query: 480 EEDWTPPDP 488
TP +P
Sbjct: 366 PTPTTPKEP 374
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 7/91 (7%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP-PRPQRPVTKARRPPP 411
P+ L P +L P P P P+ P+ PT P P P P A P
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 585
Query: 412 RPHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P A T + P P P+ PA T E P
Sbjct: 586 EP---APTTPKEPAPTTPKEPAPTTPKETAP 613
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T P
Sbjct: 527 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579
Query: 413 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 471
P + T +L P P++PA T PEE+ P +E E P+ P +E
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638
Query: 472 EGEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 639 PAPTTPKEPAPTTPKEP 655
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/135 (27%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPH 414
P P T + P P P+P K+P P+ APT P+ P T P P
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 549
Query: 415 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P P+ PA T P+E P ++ E L P+ P E
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608
Query: 474 EVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 609 PTTPEEPTPTTPEEP 623
Score = 42.7 bits (99), Expect = 9e-04
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 11/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T + P
Sbjct: 535 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
P + A T P P PEE P +E + P+ P +E
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 473 GEVKQPQEEDWTPPD 487
+ TP +
Sbjct: 648 APTTPKEPAPTTPKE 662
Score = 39.3 bits (90), Expect = 0.010
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 30/149 (20%)
Query: 357 PPPATPR----LEPRGPP------APEVVKQPVYLPSKAGPKAPTACLP-------PPRP 399
P P TP+ P+ P AP K+P +K+ P P P P P
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368
Query: 400 QRPV-TKARRPPPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLG 457
+ P T + P P + A T + P P P++PA T P+E P +E
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE---------- 417
Query: 458 PSLGATGEPEKQREEGEVKQPQEEDWTPP 486
P+ EP +E P+E T P
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 6/137 (4%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPV-YLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P T P P PAP K+P P + P P P + T + P P
Sbjct: 426 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 485
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
+ A T + P P + A T P+E P +E + P+ P +E
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPT-TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544
Query: 474 EV--KQPQEEDWTPPDP 488
K+P P P
Sbjct: 545 PTTPKEPAPTTTKKPAP 561
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 13/90 (14%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYL----PSKAGPKAPTACLPPPRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ PK P P P P A P
Sbjct: 394 PAPTTPK-----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA---PTA 445
Query: 413 PHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P + A T + P P P+ PA T E P
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 357 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAPTACLP-PPRPQRPVTKARRPPP 411
P P TP+ EP PAP K P + P P P P+ P T P
Sbjct: 363 PAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 412 RPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P A T P P+ PA T P++ P +E
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE 456
Score = 38.1 bits (87), Expect = 0.021
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)
Query: 357 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPK--APTACLPPPRPQRPVTKARRP 409
P P TP+ P+G AP +K+P P K PK APT P T +
Sbjct: 724 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPA 778
Query: 410 PPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 468
P P A T + P P P++PA T PE PP + V P+ E
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 835
Query: 469 QREEGEVKQPQEEDWTPPDPGL 490
E P+ + +P +PG+
Sbjct: 836 TPELSAEPTPKALENSPKEPGV 857
Score = 37.7 bits (86), Expect = 0.028
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 12/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR-PQRPV-TKARRPPPR-P 413
P P TP+ PAP K+P P+ APT P P P+ P T ++P P P
Sbjct: 402 PAPTTPK-----EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P + P+E P + +E + + K+
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514
Query: 474 EVKQPQEEDWTPPDP 488
K+P TP +P
Sbjct: 515 TTKEPAPT--TPKEP 527
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPR 412
P P TP+ P P PAP K+P K T P P+ P T + P
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
A T + P P+ P+ T +E P +E + P+ P +E
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 473 GEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 552 APTTTKKPAPTTPKEP 567
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 19/102 (18%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLP-------PPRPQRPVTKAR 407
P P T + P P PAP K+P P P P P P+ P +
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAPTTPKEPTPTTPKEPAPTTK 431
Query: 408 RP-PPRPHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQE 447
P P P A T + P P P+ PA T P+E P +E
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 472
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 9/84 (10%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P TP+ P P PAP K+P P+ APT P+ P T P
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTT----PKETAPTTPKGTAPTTL 676
Query: 414 HRRAETKARLPPPRPQRPAETKVP 437
A T + P P+ P TK P
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEP 700
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)
Query: 362 PRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPRPHRRAETK 420
P L P P K+P K P T P P+ P T + P P A T
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359
Query: 421 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQ 479
+ P P P+ PA T E P E P+ P +E +
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 417
Query: 480 EEDWTPPDP 488
TP +P
Sbjct: 418 PTPTTPKEP 426
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 7/91 (7%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP-PRPQRPVTKARRPPP 411
P+ L P +L P P P P+ P+ PT P P P P A P
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 412 RPHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P A T + P P P+ PA T E P
Sbjct: 638 EP---APTTPKEPAPTTPKEPAPTTPKETAP 665
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 50.4 bits (119), Expect = 4e-06
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 13/137 (9%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T P
Sbjct: 568 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620
Query: 413 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 471
P + T +L P P++PA T PEE+ P +E E P+ P +E
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679
Query: 472 EGEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 680 PAPTTPKEPAPTTPKEP 696
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/135 (27%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPH 414
P P T + P P P+P K+P P+ APT P+ P T P P
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 590
Query: 415 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P P+ PA T P+E P ++ E L P+ P E
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649
Query: 474 EVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 650 PTTPEEPTPTTPEEP 664
Score = 42.7 bits (99), Expect = 9e-04
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 11/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP----PRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ APT P P+ P T + P
Sbjct: 576 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
P + A T P P PEE P +E + P+ P +E
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688
Query: 473 GEVKQPQEEDWTPPD 487
+ TP +
Sbjct: 689 APTTPKEPAPTTPKE 703
Score = 39.3 bits (90), Expect = 0.010
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 30/149 (20%)
Query: 357 PPPATPR----LEPRGPP------APEVVKQPVYLPSKAGPKAPTACLP-------PPRP 399
P P TP+ P+ P AP K+P +K+ P P P P P
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409
Query: 400 QRPV-TKARRPPPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLG 457
+ P T + P P + A T + P P P++PA T P+E P +E
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE---------- 458
Query: 458 PSLGATGEPEKQREEGEVKQPQEEDWTPP 486
P+ EP +E P+E T P
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/137 (24%), Positives = 47/137 (34%), Gaps = 6/137 (4%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPV-YLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P T P P PAP K+P P + P P P + T + P P
Sbjct: 467 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 526
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
+ A T + P P + A T P+E P +E + P+ P +E
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPT-TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585
Query: 474 EV--KQPQEEDWTPPDP 488
K+P P P
Sbjct: 586 PTTPKEPAPTTTKKPAP 602
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/90 (32%), Positives = 35/90 (38%), Gaps = 13/90 (14%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYL----PSKAGPKAPTACLPPPRPQRPVTKARRPPPR 412
P P TP+ PAP K+P P+ PK P P P P A P
Sbjct: 435 PAPTTPK-----KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA---PTA 486
Query: 413 PHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P + A T + P P P+ PA T E P
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 516
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 7/96 (7%)
Query: 357 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAPTACLP-PPRPQRPVTKARRPPP 411
P P TP+ EP PAP K P + P P P P+ P T P
Sbjct: 404 PAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 412 RPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P A T P P+ PA T P++ P +E
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE 497
Score = 38.1 bits (87), Expect = 0.021
Identities = 41/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)
Query: 357 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPK--APTACLPPPRPQRPVTKARRP 409
P P TP+ P+G AP +K+P P K PK APT P T +
Sbjct: 765 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKELAPTTTKGPTS----TTSDKPA 819
Query: 410 PPRPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 468
P P A T + P P P++PA T PE PP + V P+ E
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 876
Query: 469 QREEGEVKQPQEEDWTPPDPGL 490
E P+ + +P +PG+
Sbjct: 877 TPELSAEPTPKALENSPKEPGV 898
Score = 37.7 bits (86), Expect = 0.028
Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 12/135 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR-PQRPV-TKARRPPPR-P 413
P P TP+ PAP K+P P+ APT P P P+ P T ++P P P
Sbjct: 443 PAPTTPK-----EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 473
A T + P P + P+E P + +E + + K+
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 555
Query: 474 EVKQPQEEDWTPPDP 488
K+P TP +P
Sbjct: 556 TTKEPAPT--TPKEP 568
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPR 412
P P TP+ P P PAP K+P K T P P+ P T + P
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
A T + P P+ P+ T +E P +E + P+ P +E
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 473 GEVKQPQEEDWTPPDP 488
+ TP +P
Sbjct: 593 APTTTKKPAPTTPKEP 608
Score = 36.2 bits (82), Expect = 0.081
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 19/102 (18%)
Query: 357 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAPTACLP-------PPRPQRPVTKAR 407
P P T + P P PAP K+P P P P P P+ P +
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPA-------PTTPKEPAPTTPKEPTPTTPKEPAPTTK 472
Query: 408 RP-PPRPHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQE 447
P P P A T + P P P+ PA T P+E P +E
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 513
Score = 35.4 bits (80), Expect = 0.14
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 9/84 (10%)
Query: 357 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
P P TP+ P P PAP K+P P+ APT P+ P T P
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTT----PKETAPTTPKGTAPTTL 717
Query: 414 HRRAETKARLPPPRPQRPAETKVP 437
A T + P P+ P TK P
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEP 741
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)
Query: 362 PRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPV-TKARRPPPRPHRRAETK 420
P L P P K+P K P T P P+ P T + P P A T
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400
Query: 421 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQ 479
+ P P P+ PA T E P E P+ P +E +
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 458
Query: 480 EEDWTPPDP 488
TP +P
Sbjct: 459 PTPTTPKEP 467
Score = 33.9 bits (76), Expect = 0.40
Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 7/91 (7%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP-PRPQRPVTKARRPPP 411
P+ L P +L P P P P+ P+ PT P P P P A P
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 412 RPHRRAETKARLP-PPRPQRPAETKVPEEIP 441
P A T + P P P+ PA T E P
Sbjct: 679 EP---APTTPKEPAPTTPKEPAPTTPKETAP 706
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 50.4 bits (119), Expect = 4e-06
Identities = 109/483 (22%), Positives = 158/483 (32%), Gaps = 94/483 (19%)
Query: 54 NGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTP 113
N Y +L P ++ P P+T P P P PP P P P
Sbjct: 599 NRPYTSLVPPLSPQPKI------VTPYTASQPSPPLPPPPPPPPPPPPPPPP----PPPP 648
Query: 114 LVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQ-AQTLVLTQTPLVWQA----PGALC-- 166
L ++ PS A+ +FV+ T A+Q + L TP V Q+ P L
Sbjct: 649 LPSQS---APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 167 GGVVCPPP-----------------------LLLAAAPVVPVMAAQVVGGTQACEGGWSQ 203
GVV PPP L +AP P+ QV TQ
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765
Query: 204 GLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRL 263
P+P P PP A P+V+ P P + + A P P F
Sbjct: 766 PPPIPAPLPPQAPPKPLVTI----PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF-- 819
Query: 264 WQHYKPLARRHLPQSPDTEALSCF--LIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNF 321
++P SP T + +P +S + P L
Sbjct: 820 -------PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV-------------- 858
Query: 322 DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYL 381
+ ++A +F M+ Q + + P + +P+ P+ V P +
Sbjct: 859 -PSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917
Query: 382 P-----SKAGPKAPTACLPPPRPQRPVT------KARRPPPRPHRRAETKARLPPPRPQR 430
P S P P + +P P P P T K+ P + + + + PPP PQR
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Query: 431 PAETKVPEEIP-PEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPG 489
+ K PE + VD + P +G P K E P PP PG
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPP-AESGSPSK-----ETLPPPA---APPKPG 1028
Query: 490 LLS 492
L+
Sbjct: 1029 KLN 1031
Score = 38.1 bits (87), Expect = 0.021
Identities = 88/441 (19%), Positives = 137/441 (31%), Gaps = 57/441 (12%)
Query: 81 TTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCG---PSGAG-ASNVFVQMR 136
T P P P + PP P P L +Q C PS +V Q+
Sbjct: 807 TPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866
Query: 137 TEVGPVK---AAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGG 193
++ P A ++Q L + Q+P A+ P + +P P +
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE---- 922
Query: 194 TQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQA----KAPPD 249
L PPPPP PP A P P + G S + K PP
Sbjct: 923 ---------SSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Query: 250 DSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLW 309
S+ + A P+ P ++L P S + K T+
Sbjct: 974 TPQRNSSIKSSSG--------AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Query: 310 RAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 369
+ + N ++ + + + P P + P P
Sbjct: 1026 KPGKLNLSGVNLPGVLQQGCVSA--------KAPVLSGRGKDSVVEFPSPPSDSDFPPPP 1077
Query: 370 PAPEVVKQPVYLPSK-AGPKAPTACLPPPRPQ---RPVTKARRPPPRPHRRAETK----- 420
P E+ P+ +P+ +G +P + P+PQ + K PP RP R T+
Sbjct: 1078 PETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAE 1137
Query: 421 ----ARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVK 476
+ PQ P K + P + D+ L S+ G + E
Sbjct: 1138 ISEQPTMATVVPQVPTSPKSSLSVQPGFL---ADLNRTLQRKSITRHGSLSSRMSRAEPT 1194
Query: 477 QPQEE-DWTPPDPGLLSYTDK 496
++ PP P LLS K
Sbjct: 1195 ATMDDMALPPPPPELLSDQQK 1215
Score = 31.2 bits (69), Expect = 2.6
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 7/83 (8%)
Query: 349 WMKGPQCLPPPATPRLEPRGPP----APEVVKQP-VYLPSKAG-PKAPTACLPPPRPQRP 402
W +G Q L + R+E P P + QP + P A P P PPP P P
Sbjct: 581 WKRGTQ-LEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP 639
Query: 403 VTKARRPPPRPHRRAETKARLPP 425
PPP P + A + P
Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAP 662
Score = 29.3 bits (64), Expect = 9.9
Identities = 46/174 (26%), Positives = 69/174 (39%), Gaps = 27/174 (15%)
Query: 209 PPPPPAAQLP------PIVSQGNAGPWPQGAHGEGSLAS--SQAKAPPDDSCNPRSVYEN 260
PPPPP +LP P V GN P + + S S KAPP P+ ++
Sbjct: 1074 PPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPP--PTRPKR-NDS 1130
Query: 261 FRLWQ---HYKPLARRHLPQSPDTEALSC-----FLIPVLRSLARRKPTMTLEEGLWRAM 312
RL Q +P +PQ P + S FL + R+L R+ ++T L M
Sbjct: 1131 TRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRK--SITRHGSLSSRM 1188
Query: 313 REWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCL---PPPATPR 363
+ T+ D M + L ++++ + G L PPPA P+
Sbjct: 1189 SRAEPTATMDDMALPPPPPELL---SDQQKAGYGGSHISGYATLRRGPPPAPPK 1239
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 49.7 bits (117), Expect = 7e-06
Identities = 40/123 (32%), Positives = 51/123 (41%), Gaps = 12/123 (9%)
Query: 325 IFYEMAEKFLEFEA-EEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPS 383
+ Y+ EK EA + E++ Q + PPP P GPP P + P
Sbjct: 254 VIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGA--PP 311
Query: 384 KAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAET-KVPEEIPP 442
+APTA PPP P RP PPP P+R PPP P P+ P PP
Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAV--PPPPPNR------MYPPPPPALPSSAPSGPPPPPP 363
Query: 443 EVV 445
V+
Sbjct: 364 SVL 366
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 7/86 (8%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PPP P RG P P + P P P P+ +PPP P R PPP P
Sbjct: 299 PPP--PPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNR-----MYPPPPPALP 351
Query: 417 AETKARLPPPRPQRPAETKVPEEIPP 442
+ + PPP P V PP
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPP 377
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/132 (34%), Positives = 51/132 (38%), Gaps = 25/132 (18%)
Query: 364 LEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR---PQRPVTKARRPPPRPHRRAETK 420
L + PP P PS+ GP P PPP P P + R PP P RA T
Sbjct: 272 LRRQAPPPPP--------PSRGGPPPPP---PPPHNSGPPPPPARGRGAPPPPPSRAPTA 320
Query: 421 ARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE---EGEVKQ 477
A PPP P RP+ VP PP + Y L PS +G P G V
Sbjct: 321 AP-PPPPPSRPS-VAVP---PPPPNRMYPPPPPAL--PSSAPSGPPPPPPSVLGVGPVAP 373
Query: 478 PQEEDWTPPDPG 489
P PP PG
Sbjct: 374 PPPPP-PPPPPG 384
Score = 37.4 bits (85), Expect = 0.036
Identities = 19/56 (33%), Positives = 26/56 (46%)
Query: 192 GGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247
GG +A + + P PPPP PP N+GP P A G G+ ++AP
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP 318
Score = 37.0 bits (84), Expect = 0.048
Identities = 24/55 (43%), Positives = 24/55 (43%), Gaps = 12/55 (21%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPP 411
PPPA P P GPP P P L GP AP PPP P P PPP
Sbjct: 346 PPPALPSSAPSGPPPPP----PSVLG--VGPVAPPPPPPPPPPPGP------PPP 388
Score = 35.4 bits (80), Expect = 0.14
Identities = 24/81 (29%), Positives = 27/81 (33%), Gaps = 16/81 (19%)
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPP 410
+ P PPP PP+ V P P P PPP P P + PP
Sbjct: 316 RAPTAAPPPP--------PPSRPSVAVP--------PPPPNRMYPPPPPALPSSAPSGPP 359
Query: 411 PRPHRRAETKARLPPPRPQRP 431
P P PPP P P
Sbjct: 360 PPPPSVLGVGPVAPPPPPPPP 380
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 17/82 (20%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQR-----PVTKARRPPP 411
PPP+ P + PP + P P AP+ PPP P PV PPP
Sbjct: 325 PPPSRPSVAVPPPPPNRMYPPP---PPALPSSAPSG--PPPPPPSVLGVGPVAPPPPPPP 379
Query: 412 RPHRRAETKARLPPPRPQRPAE 433
P PPP P P++
Sbjct: 380 PPPPG-------PPPPPGLPSD 394
Score = 31.2 bits (69), Expect = 2.6
Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 172 PPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPP 219
PPP L ++AP P V G G + P PPPPPP PP
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGV----GPVAPPPPPPPPPPPGPPPPP 389
Score = 30.8 bits (68), Expect = 3.4
Identities = 33/137 (24%), Positives = 40/137 (29%), Gaps = 26/137 (18%)
Query: 83 PAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPV 142
P P P+ G G PP P ++ P P + P + A P
Sbjct: 278 PPPPPSRG------GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331
Query: 143 KAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 202
A P P + G PPP +L PV P
Sbjct: 332 VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPP----------------- 374
Query: 203 QGLPLPPPPPPAAQLPP 219
P PPPPPP PP
Sbjct: 375 ---PPPPPPPPPGPPPP 388
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 49.3 bits (116), Expect = 9e-06
Identities = 44/162 (27%), Positives = 53/162 (32%), Gaps = 20/162 (12%)
Query: 347 SQWMKGPQCLPPPATPRLEPRGPPAPEVV---KQPVYLPSKAGPKAPTACLPPPRPQRPV 403
S MK PPP P PP P + K P Y K P P L P R P
Sbjct: 167 STGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPA 226
Query: 404 TKARRPPPRPHR-----RAETKARLPPPRPQRPAETKVP----EEIPPEVVQEYVDIMEE 454
+PPP P ++ A PPP Q P P E PE+ Q + + +
Sbjct: 227 PPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRK 286
Query: 455 LLGPSLGATGEPE--------KQREEGEVKQPQEEDWTPPDP 488
GP G P R + P PP P
Sbjct: 287 TPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPP 328
Score = 44.7 bits (104), Expect = 2e-04
Identities = 56/229 (24%), Positives = 78/229 (34%), Gaps = 40/229 (17%)
Query: 351 KGPQCLPP------PATPRLEPRGP---PAPEVVKQPVYLPSKAGPKAPTACLPPPRPQR 401
+GP PP P R P G P P +QP +P+ GP +PT P PQR
Sbjct: 222 EGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPN--GPSSPTNESAPELPQR 279
Query: 402 ----------PVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDI 451
PV PPP + R PPP P+ P PP + D
Sbjct: 280 HNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDA 339
Query: 452 --------MEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDF 503
M PS G P + G PP P + D + + + F
Sbjct: 340 PPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPP-------PPPPPLRNGHRDSITTVRSF 392
Query: 504 VTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQGAPSDAP 552
+ E+ +E+ +P+ F Q + + A+GAP P
Sbjct: 393 LDDFESKYSFHPVEDFPAPEEYKHF----QRIYPSKTNRAARGAPPLPP 437
Score = 29.6 bits (65), Expect = 7.6
Identities = 11/21 (52%), Positives = 12/21 (57%)
Query: 205 LPLPPPPPPAAQLPPIVSQGN 225
+P PPPPPP PP Q N
Sbjct: 3 IPPPPPPPPGPPPPPTFHQAN 23
Score = 29.6 bits (65), Expect = 7.6
Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 9/116 (7%)
Query: 359 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAE 418
P PR++ P P++ + S G K ++ PPP P R P P +A
Sbjct: 146 PELPRMQR--PSLPDLSRPNT--TSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAP 201
Query: 419 TKAR---LPPPRPQR--PAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 469
R LPP QR P P P + V+I G SL P +Q
Sbjct: 202 AYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQ 257
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
Length = 1086
Score = 48.9 bits (115), Expect = 1e-05
Identities = 96/418 (22%), Positives = 138/418 (33%), Gaps = 94/418 (22%)
Query: 60 LGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQD 119
+G GV A P + + +P P P L + P GG
Sbjct: 733 VGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLP---PQGG----------------- 772
Query: 120 GCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGG---VVCPPPLL 176
G PS A + +F +A Q + + Q P AP GG PP +
Sbjct: 773 GKPPSSAQTAEIF----------QALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVP 822
Query: 177 LAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE 236
+ P P + + W P P PP P+ QG+ P P G
Sbjct: 823 IPPRPTRPHVQLSPAPPGEEETSQW----PGPASPPRVPPREPLSPQGSRTPSPLVPPGS 878
Query: 237 GSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLA 296
L PP S +P + + A + Q+P A C ++P++R
Sbjct: 879 SPL-------PPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPC-ILPIVRDGK 930
Query: 297 RRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCL 356
+ T + +R + E ++FL E ++ + P L
Sbjct: 931 KVSST--------------HYYLLPERPSYLERYQRFL----REAQSPEEPTPLPVPLLL 972
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPP---RPQRPVTKARRPPPRP 413
PPP+TP P AP +P+ P A L P AR PPPR
Sbjct: 973 PPPSTP-----APAAPTATVRPM----------PQAALDPKANFSTNNSNPGARPPPPR- 1016
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 471
ARL PQR PE P + + ++E+L G L GE K E
Sbjct: 1017 -----ATARL----PQRGCPGDGPEAGRP---ADKIQMVEQLFGLGLRPRGECHKVLE 1062
Score = 32.7 bits (73), Expect = 0.90
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 359 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVT--KARRPPPRP 413
P P L P P ++ L + P++PT LP P PV AR PP P
Sbjct: 655 PVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPP 711
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/94 (36%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 351 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRP- 409
K P PP TP+ +P PP P QP LPS APT PPP P P P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPP---PQPA-LPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511
Query: 410 PPRPHRRAETKARLPPPRPQRPA--ETKVPEEIP 441
PP P A PP P P+ + ++P+ P
Sbjct: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
Score = 47.0 bits (110), Expect = 5e-05
Identities = 89/334 (26%), Positives = 123/334 (36%), Gaps = 50/334 (14%)
Query: 125 GAGASNV--FVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPP-----LLL 177
GAGA + F+Q P A Q T L+ +A G V+ PPP +L
Sbjct: 750 GAGAKELGAFLQKSPPPPPPTAQSTQP---TPHGLLLEAGGPDLPLVLPPPPPQLLPSVL 806
Query: 178 AAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEG 237
+ AP A++V G E G P PPPPPP PP+ Q A +HG
Sbjct: 807 SHAPSPSPSASKV--GVHLLEPATRDGAPQPPPPPPPPP-PPMPLQLEA---HLRSHGLE 860
Query: 238 SLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLAR 297
A S P + P ++ E + P P++E + A
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKD-------PAGAY 913
Query: 298 RKPTMTLEEGLWRAMREWQHTS---------NFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 348
R P+ +G +A R TS + +R F M E F A++ + +
Sbjct: 914 RSPS---PQGT-KAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPE 969
Query: 349 WMKGPQ--CLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPR-PQRPVTK 405
P+ PPP P +P GP P S AGP+ P L P + P+ P T
Sbjct: 970 DEGDPKAGAGPPPGPPAYDPYGPYCPG-------RASGAGPETPGLGLDPNKPPELPSTV 1022
Query: 406 ARRP----PPRPHRRAETKARLPPPRPQRPAETK 435
P PH+ A PPP P +E K
Sbjct: 1023 NAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/83 (31%), Positives = 28/83 (33%)
Query: 359 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAE 418
P P LE + PP P P P P A PP P + PPP P
Sbjct: 1448 PEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Query: 419 TKARLPPPRPQRPAETKVPEEIP 441
PPP P A P E P
Sbjct: 1508 AMPSPPPPPPPAAAPLAAPPEEP 1530
Score = 38.5 bits (88), Expect = 0.016
Identities = 63/268 (23%), Positives = 90/268 (33%), Gaps = 52/268 (19%)
Query: 172 PPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQ 231
PPP A P P + G G + GL L P PP +LP V+ G
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGA-----GPETPGLGLDPNKPP--ELPSTVNAEPLGLIQS 1032
Query: 232 GAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPV 291
G H QA PP P P +P +E P+
Sbjct: 1033 GPH--------QAAPPPPPPPPP---------------------PPAPASEPKGGLTSPI 1063
Query: 292 LRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 351
S KP L+ + +R + ++ A+++ EFEA+E+ +
Sbjct: 1064 FCST---KPKKLLKTSSFHLLRRRDPPFQTPKKLY---AQEY-EFEADEDKADVPADIRL 1116
Query: 352 GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPP 411
P+ LP + R PA + + P GP P R ++P R PP
Sbjct: 1117 NPRRLPDLVS---SCRSRPALSPLGDIDFCPPNPGPDGPRR-----RGRKPTKAKRDGPP 1168
Query: 412 RPHRRAETKARLPPPRPQRPAETKVPEE 439
RP R + L P PA P +
Sbjct: 1169 RPRGRPRIRP-LEVPTTAGPASASTPTD 1195
Score = 38.1 bits (87), Expect = 0.021
Identities = 29/98 (29%), Positives = 35/98 (35%), Gaps = 3/98 (3%)
Query: 353 PQCLPPPATPRLEPRGP-PAPEVVKQPVYLPSKA--GPKAPTACLPPPRPQRPVTKARRP 409
PQ PPP P +P P P P V P P P P PPP P P
Sbjct: 1467 PQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526
Query: 410 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 447
P P + LP RP A+ + + E +E
Sbjct: 1527 PEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEE 1564
Score = 37.4 bits (85), Expect = 0.036
Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 8/103 (7%)
Query: 352 GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSK----AGPKAPTACLPPPRPQRPVTKAR 407
GP L P TP P GPP P P +LP++ A A A PQ
Sbjct: 215 GPAGLGPAQTPPYRP-GPPDPP--PPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGA 271
Query: 408 RPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPP-EVVQEYV 449
P P P RA + QRPA + P PP +Q Y+
Sbjct: 272 APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYL 314
Score = 37.4 bits (85), Expect = 0.036
Identities = 27/93 (29%), Positives = 32/93 (34%), Gaps = 14/93 (15%)
Query: 357 PPPATPRLEPRGPPAPEV-------VKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRP 409
PP A P PP P + +P L K P P A P P+P P
Sbjct: 1422 PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP-------PP 1474
Query: 410 PPRPHRRAETKARLPPPRPQRPAETKVPEEIPP 442
PP P + L P P P +P PP
Sbjct: 1475 PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Score = 34.7 bits (78), Expect = 0.24
Identities = 99/419 (23%), Positives = 140/419 (33%), Gaps = 115/419 (27%)
Query: 81 TTPAPGPAHGPLLVTAGAPP--GGPLVLSN-FPSTPLVTEQDGCGPSGAGASNVFVQMRT 137
T+ GP P G PP G P SN P PL+ E+ P A
Sbjct: 1416 TSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ------- 1468
Query: 138 EVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQAC 197
P Q + + PLV P + PPPL P +P
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSS-----PPPPPLPPPPPPAMPS------------ 1511
Query: 198 EGGWSQGLPLPPPPPPAAQL--PPIVSQGNAGPWPQGAHGEGS----LASSQAKAP---- 247
P PPPPP AA L PP + A P P+ + LA Q A
Sbjct: 1512 --------PPPPPPPAAAPLAAPP---EEPAAPSPEDPELPDTRPLHLAKKQETAAVCGE 1560
Query: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLI------PVLR--SLARRK 299
D+ FR + + ++ D +L L P+ R +K
Sbjct: 1561 TDEEAGESGGEGIFRERDEF-------VIRAEDIPSLKLALQTGREPPPIWRVQKALLQK 1613
Query: 300 PTMTLEEGLWRAMREWQHTSNF------DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGP 353
T +++G R++ TSN+ + + + KFLE + K +++
Sbjct: 1614 FTPEIKDG----QRQFCATSNYLGYFGDAKNRYQRLYVKFLE-------NVNKKDYVR-- 1660
Query: 354 QCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRP 413
R PP P P AG + PPP KA PPP+P
Sbjct: 1661 ------VCARKPWHRPPVPVRRSGQAKNPVSAGGSSA----PPP-------KAPAPPPKP 1703
Query: 414 HRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 472
+T + P P++ ET +PE PE PSL E EK++E+
Sbjct: 1704 ETPEKTTSEKP---PEQTPETAMPEPPAPE-------------KPSLLRPVEKEKEKEK 1746
Score = 34.7 bits (78), Expect = 0.24
Identities = 38/135 (28%), Positives = 50/135 (37%), Gaps = 16/135 (11%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PP TP PPAPE +P L K RP R RP R
Sbjct: 1714 PPEQTPETAMPEPPAPE---KPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERS 1770
Query: 417 AET----KARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE- 471
T +RLP RP TKV E PP+ +++ ++E G + G P +
Sbjct: 1771 LATGQPATSRLPKARP-----TKVKAEPPPKKRKKW---LKEAGGNATAGGGPPGSSSDS 1822
Query: 472 EGEVKQPQEEDWTPP 486
E P E++ P
Sbjct: 1823 ESSPGAPSEDERAVP 1837
Score = 29.6 bits (65), Expect = 7.6
Identities = 34/142 (23%), Positives = 46/142 (32%), Gaps = 41/142 (28%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPH-- 414
PPP P + P ++ + GP P PPP P + P P P
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEA------GGPDLPLVLPPPPPQLLPSVLSHAPSPSPSAS 817
Query: 415 -----------RRAETKARLPPPRPQRPAETKV-------------------PEEI--PP 442
R + PPP P P ++ PEE PP
Sbjct: 818 KVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPP 877
Query: 443 EVVQEYVDIMEELLGPSLGATG 464
+QE + +E L P+ G TG
Sbjct: 878 GAMQELLGALEP-LPPAPGDTG 898
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 47.4 bits (111), Expect = 4e-05
Identities = 84/359 (23%), Positives = 139/359 (38%), Gaps = 74/359 (20%)
Query: 206 PLPPP--------PP--PAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAPPDDSCNPR 255
P+PPP PP P +P + S +AGP P + A+ P + N
Sbjct: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709
Query: 256 SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREW 315
+ + + R LP P+ P+L PT+ +E +
Sbjct: 710 GLSVPGLV-----SVPPRLLP-GPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRP 763
Query: 316 QHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPP-----ATPRLEPRGPP 370
++D+ ++ E LE ++++ + I +G LPPP P + P GPP
Sbjct: 764 AFV-HYDKEEASDV-EISLESDSDDSVVIVP----EGLPPLPPPPPSGATPPPIAPTGPP 817
Query: 371 --APEVV--KQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPP 426
+P V ++P LP+ GP LPPP P PPP P LPPP
Sbjct: 818 TASPPVPAKEEPEELPAAPGP------LPPPPPP--------PPPVP-----GPVTLPPP 858
Query: 427 RPQRPAETKVPEEIP----PEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEED 482
+ VPE P P ++E + ++ + S E E++ EE E ++ +EED
Sbjct: 859 Q-------LVPEGTPGGGGPPALEEDLTVIN--INSSDEEEEEEEEEEEEEEEEEEEEED 909
Query: 483 WTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGL 541
+ + Y ++ E +F EE + +++ ++ E+EE L
Sbjct: 910 FEEEEEDEEEYFEE-----------EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Score = 43.5 bits (101), Expect = 5e-04
Identities = 107/475 (22%), Positives = 163/475 (34%), Gaps = 93/475 (19%)
Query: 51 MASNGAYPALGPGVTANPG-------TSLSV---FTALPFTTPAP-----GPAHGPLLVT 95
M S G P+ GP +A PG LSV + P P P G P+L
Sbjct: 683 MPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742
Query: 96 AGAPPGGPLVLSNFPSTPLVTEQDGCGPSGA-------GASNVFVQMRTEVGPVKAAQAQ 148
+G PP P+ P G P A AS+V + + ++
Sbjct: 743 SGTPP---------PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD-------SDD 786
Query: 149 TLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLP 208
++V+ L P G PPP+ AP P A+ V + E + PLP
Sbjct: 787 SVVIVPEGLPPLPPPPPSGAT--PPPI----APTGPPTASPPVPAKEEPEELPAAPGPLP 840
Query: 209 PPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYK 268
PPPPP +P V+ P+G G G + + N S E + +
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDL---TVININSSDEEEEEEEEEE 897
Query: 269 PLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYE 328
+ D E EE E + F+ E
Sbjct: 898 EEEEEEEEEEEDFEE------------EEEDEEEYFEE-------EEEEEEEFEEEFEEE 938
Query: 329 MAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPK 388
E E E E+E + ++ + ++ + A +E PP P + P LP P+
Sbjct: 939 EGELEEEEEEEDEEEEEELEEVEDLEF--GTAGGEVEEGAPPPPTL---PPALPP---PE 990
Query: 389 APTACLPPPRPQRP-VTKARRPPPRPHRRAETKARLPPP----------RPQRPAETKVP 437
+P P P P+ + + P R A+T L P + PA P
Sbjct: 991 SPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPP 1050
Query: 438 EEI-------PPEVVQEYVDIMEELLGPSLGATGEPEKQRE-EGEVKQPQEEDWT 484
+E+ PP +++E + + + P E E + E E E Q +E+D T
Sbjct: 1051 QELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDT 1105
>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
Length = 389
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/89 (37%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 340 EEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKAPTACLPPPR 398
+ +Q + S+ G + LPP + P EPR P A + P P + G P +P PPR
Sbjct: 124 QAVQPRPSEPTPGSEALPPGSLPEGEPR-PYALPPRESPAPRPFRWGDPFSPA----PPR 178
Query: 399 PQRPVTKARRPPPRPHRRAETKARLPPPR 427
PQ P A +PP RP R+ R P PR
Sbjct: 179 PQPPSRPAAQPPSRPAFRSPRPVRGPHPR 207
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/80 (38%), Positives = 35/80 (43%), Gaps = 23/80 (28%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PPP PR PR PP P P P P LPPPRP +P PPPRP +
Sbjct: 25 PPPLPPRKPPR-PPKP---------PRPLPPNPPRPPLPPPRPPKPPL----PPPRPPK- 69
Query: 417 AETKARLPPPRPQRPAETKV 436
PP P A++KV
Sbjct: 70 --------PPSPLGLAQSKV 81
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 10/65 (15%)
Query: 379 VYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPE 438
V+ P G +P LPP +P RP R PP P R LPPPRP +P +P
Sbjct: 15 VFFP--CGLWSPPPPLPPRKPPRPPKPPRPLPPNPPR-----PPLPPPRPPKP---PLPP 64
Query: 439 EIPPE 443
PP+
Sbjct: 65 PRPPK 69
Score = 36.6 bits (83), Expect = 0.062
Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 378 PVYLPSKAGPKAPTACLPPPRPQRPV----TKARRPPPRPHRRAETKARLPPPRPQRP 431
P L S P P PP+P RP+ + PPPRP K LPPPRP +P
Sbjct: 18 PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRP-----PKPPLPPPRPPKP 70
>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
sapiens]
Length = 218
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/80 (38%), Positives = 35/80 (43%), Gaps = 23/80 (28%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PPP PR PR PP P P P P LPPPRP +P PPPRP +
Sbjct: 25 PPPLPPRKPPR-PPKP---------PRPLPPNPPRPPLPPPRPPKPPL----PPPRPPK- 69
Query: 417 AETKARLPPPRPQRPAETKV 436
PP P A++KV
Sbjct: 70 --------PPSPLGLAQSKV 81
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 10/65 (15%)
Query: 379 VYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPE 438
V+ P G +P LPP +P RP R PP P R LPPPRP +P +P
Sbjct: 15 VFFP--CGLWSPPPPLPPRKPPRPPKPPRPLPPNPPR-----PPLPPPRPPKP---PLPP 64
Query: 439 EIPPE 443
PP+
Sbjct: 65 PRPPK 69
Score = 36.6 bits (83), Expect = 0.062
Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 378 PVYLPSKAGPKAPTACLPPPRPQRPV----TKARRPPPRPHRRAETKARLPPPRPQRP 431
P L S P P PP+P RP+ + PPPRP K LPPPRP +P
Sbjct: 18 PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRP-----PKPPLPPPRPPKP 70
>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
sapiens]
Length = 218
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/80 (38%), Positives = 35/80 (43%), Gaps = 23/80 (28%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRR 416
PPP PR PR PP P P P P LPPPRP +P PPPRP +
Sbjct: 25 PPPLPPRKPPR-PPKP---------PRPLPPNPPRPPLPPPRPPKPPL----PPPRPPK- 69
Query: 417 AETKARLPPPRPQRPAETKV 436
PP P A++KV
Sbjct: 70 --------PPSPLGLAQSKV 81
Score = 38.5 bits (88), Expect = 0.016
Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 10/65 (15%)
Query: 379 VYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPE 438
V+ P G +P LPP +P RP R PP P R LPPPRP +P +P
Sbjct: 15 VFFP--CGLWSPPPPLPPRKPPRPPKPPRPLPPNPPR-----PPLPPPRPPKP---PLPP 64
Query: 439 EIPPE 443
PP+
Sbjct: 65 PRPPK 69
Score = 36.6 bits (83), Expect = 0.062
Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 9/58 (15%)
Query: 378 PVYLPSKAGPKAPTACLPPPRPQRPV----TKARRPPPRPHRRAETKARLPPPRPQRP 431
P L S P P PP+P RP+ + PPPRP K LPPPRP +P
Sbjct: 18 PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRP-----PKPPLPPPRPPKP 70
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/163 (25%), Positives = 61/163 (37%), Gaps = 24/163 (14%)
Query: 337 EAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP 396
+ + ++Q +Q+ +GP PPP P +P PP P+ QP LP P A PP
Sbjct: 1259 DGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQ---QPPPLPQLGSIPPPPASAPP 1315
Query: 397 PRPQR------PVTKAR-----RPPPRPHRRAETKARLPP--------PRPQRPAETKVP 437
P R PV + RP P R A + P P P + P
Sbjct: 1316 VGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAP 1375
Query: 438 EEIP--PEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQP 478
+ P + + ++ + P+ GA G P + G P
Sbjct: 1376 QHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHP 1418
Score = 33.1 bits (74), Expect = 0.69
Identities = 27/94 (28%), Positives = 33/94 (35%), Gaps = 17/94 (18%)
Query: 386 GPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVV 445
GP AP LPP +P P PPP+ PPP PQ + P PP
Sbjct: 1276 GP-APPPYLPPQQPSLP------PPPQQ----------PPPLPQLGSIPPPPASAPPVGP 1318
Query: 446 QEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQ 479
+ + GP G P + G PQ
Sbjct: 1319 HRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQ 1352
>gi|77681565 NG5 protein [Homo sapiens]
Length = 306
Score = 45.1 bits (105), Expect = 2e-04
Identities = 57/170 (33%), Positives = 63/170 (37%), Gaps = 18/170 (10%)
Query: 58 PALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTE 117
P LG G A+ + + T P P P H P AGAPP G L P P + E
Sbjct: 57 PRLGAGGLASSAATAQRGPSSSATLPRP-PHHAPPGPAAGAPPPGCATLPRMPPDPYLQE 115
Query: 118 QDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVL-TQTPLVWQAPGALCGGVVCPP-PL 175
GP P + AQA V+ T V P GG V P PL
Sbjct: 116 TRFEGPLPPPPPAAAAP--PPPAPAQTAQAPGFVVPTHAGTVGTLP---LGGYVAPGYPL 170
Query: 176 LL----AAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPP--PPAAQLPP 219
L A PV PV GGT GG LPPPP P A L P
Sbjct: 171 QLQPCTAYVPVYPV-GTPYAGGT---PGGTGVTSTLPPPPQGPGLALLEP 216
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/90 (35%), Positives = 35/90 (38%), Gaps = 16/90 (17%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPR 412
P PPPA P P PP P P Y P+ PPP P+ P T A PP
Sbjct: 491 PASFPPPAIPPPTPGYPPPP-----PTYNPN----------FPPPPPRLPPTHA-VPPHP 534
Query: 413 PHRRAETKARLPPPRPQRPAETKVPEEIPP 442
P A PPP + VP IPP
Sbjct: 535 PPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 337 EAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPP 396
++ E Q Q+ + Q P P+ P +P VK+ V + PK P
Sbjct: 295 QSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVV----SPKEENKAAEP 350
Query: 397 PRPQRPVTKARRPP-----PRPHRRAETKARLPPPRPQRPAE-TKVPE-EIPP 442
P P+ P + PP P P R+ A L P P + T +P+ +IPP
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPP 403
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 18/75 (24%)
Query: 357 PPPATPRLEPRGPPAPEVVKQPVYLPSKA---------GP----KAPTACLPPPRPQRPV 403
PPP P++E PP P P P A GP P +PPP PV
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
Query: 404 TKA-----RRPPPRP 413
+ R PPP P
Sbjct: 411 HQPPPLPHRPPPPPP 425
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/82 (36%), Positives = 36/82 (43%), Gaps = 15/82 (18%)
Query: 353 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQR------PVTKA 406
P P P P + +G PAP P KAG K+ PPP P + PV +
Sbjct: 608 PSPTPSPHRPSIRTKGEPAPP--------PGKAGEKSVKKPAPPPAPPQATKTTAPVPEP 659
Query: 407 RRP-PPRPHRRAETKARLPPPR 427
+P PR RR E AR PP R
Sbjct: 660 TKPGDPREARRKERPARTPPRR 681
Score = 35.0 bits (79), Expect = 0.18
Identities = 25/99 (25%), Positives = 34/99 (34%), Gaps = 24/99 (24%)
Query: 395 PPPRPQRPVTKAR-RPPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIME 453
P P P RP + + P P P + E + P P P P TK +P
Sbjct: 610 PTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVP------------ 657
Query: 454 ELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLS 492
EP K + E ++ + TPP LS
Sbjct: 658 -----------EPTKPGDPREARRKERPARTPPRRRTLS 685
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,155,689
Number of Sequences: 37866
Number of extensions: 2226363
Number of successful extensions: 24680
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 347
Number of HSP's successfully gapped in prelim test: 1123
Number of HSP's that attempted gapping in prelim test: 13064
Number of HSP's gapped (non-prelim): 9226
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.