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Search of human proteins with 134244285
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134244285 Notch homolog 3 [Homo sapiens]
(2321 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134244285 Notch homolog 3 [Homo sapiens] 5103 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 2486 0.0
gi|24041035 notch 2 preproprotein [Homo sapiens] 2469 0.0
gi|55770876 notch4 preproprotein [Homo sapiens] 1173 0.0
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 530 e-150
gi|4557679 jagged 1 precursor [Homo sapiens] 517 e-146
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 477 e-134
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 462 e-129
gi|66346695 fibrillin 2 precursor [Homo sapiens] 461 e-129
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 453 e-126
gi|56237021 fibrillin 3 precursor [Homo sapiens] 446 e-125
gi|24430141 fibrillin 1 precursor [Homo sapiens] 446 e-124
gi|122937283 6720455I24Rik homolog [Homo sapiens] 443 e-123
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 351 5e-96
gi|112420992 crumbs homolog 2 [Homo sapiens] 336 1e-91
gi|110347437 latent transforming growth factor beta binding prot... 305 3e-82
gi|110347412 latent transforming growth factor beta binding prot... 305 3e-82
gi|110347431 latent transforming growth factor beta binding prot... 305 3e-82
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 279 2e-74
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 279 3e-74
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 269 2e-71
gi|110735443 delta-like 1 [Homo sapiens] 268 5e-71
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 266 2e-70
gi|148886654 polydom [Homo sapiens] 265 3e-70
gi|4557733 latent transforming growth factor beta binding protei... 256 2e-67
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 240 1e-62
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 238 4e-62
gi|46249414 latent transforming growth factor beta binding prote... 227 1e-58
gi|46249412 latent transforming growth factor beta binding prote... 227 1e-58
gi|194328809 latent transforming growth factor beta binding prot... 219 2e-56
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 5103 bits (13236), Expect = 0.0
Identities = 2321/2321 (100%), Positives = 2321/2321 (100%)
Query: 1 MGPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPS 60
MGPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPS
Sbjct: 1 MGPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPS 60
Query: 61 REAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP 120
REAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP
Sbjct: 61 REAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP 120
Query: 121 DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 180
DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS
Sbjct: 121 DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 180
Query: 181 FRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC 240
FRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC
Sbjct: 181 FRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC 240
Query: 241 PGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSC 300
PGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSC
Sbjct: 241 PGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSC 300
Query: 301 VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360
VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC
Sbjct: 301 VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360
Query: 361 HEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG 420
HEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG
Sbjct: 361 HEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG 420
Query: 421 RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN 480
RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN
Sbjct: 421 RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN 480
Query: 481 GGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGT 540
GGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGT
Sbjct: 481 GGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGT 540
Query: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL
Sbjct: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
Query: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE 660
VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE
Sbjct: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE 660
Query: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 720
CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVC 720
Query: 721 EPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPC 780
EPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPC
Sbjct: 721 EPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPC 780
Query: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG 840
EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG
Sbjct: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG 840
Query: 841 YTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900
YTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT
Sbjct: 841 YTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900
Query: 901 CTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
CTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ
Sbjct: 901 CTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
Query: 961 HEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA 1020
HEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA
Sbjct: 961 HEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA 1020
Query: 1021 YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH 1080
YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH
Sbjct: 1021 YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH 1080
Query: 1081 CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDL 1140
CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDL
Sbjct: 1081 CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDL 1140
Query: 1141 VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200
VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL
Sbjct: 1141 VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200
Query: 1201 RCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQ 1260
RCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQ
Sbjct: 1201 RCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQ 1260
Query: 1261 CRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS 1320
CRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS
Sbjct: 1261 CRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLS 1320
Query: 1321 GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPE 1380
GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPE
Sbjct: 1321 GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPE 1380
Query: 1381 VSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNS 1440
VSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNS
Sbjct: 1381 VSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNS 1440
Query: 1441 RCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDC 1500
RCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDC
Sbjct: 1441 RCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDC 1500
Query: 1501 ASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYHR 1560
ASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYHR
Sbjct: 1501 ASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYHR 1560
Query: 1561 PSPGSEPRARRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERL 1620
PSPGSEPRARRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERL
Sbjct: 1561 PSPGSEPRARRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERL 1620
Query: 1621 DFPYPLRDVRGEPLEPPEPSVPLLPLLVAGAVLLLVILVLGVMVARRKREHSTLWFPEGF 1680
DFPYPLRDVRGEPLEPPEPSVPLLPLLVAGAVLLLVILVLGVMVARRKREHSTLWFPEGF
Sbjct: 1621 DFPYPLRDVRGEPLEPPEPSVPLLPLLVAGAVLLLVILVLGVMVARRKREHSTLWFPEGF 1680
Query: 1681 SLHKDVASGHKGRREPVGQDALGMKNMAKGESLMGEVATDWMDTECPEAKRLKVEEPGMG 1740
SLHKDVASGHKGRREPVGQDALGMKNMAKGESLMGEVATDWMDTECPEAKRLKVEEPGMG
Sbjct: 1681 SLHKDVASGHKGRREPVGQDALGMKNMAKGESLMGEVATDWMDTECPEAKRLKVEEPGMG 1740
Query: 1741 AEEAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCG 1800
AEEAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCG
Sbjct: 1741 AEEAVDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCG 1800
Query: 1801 GALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLD 1860
GALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLD
Sbjct: 1801 GALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLD 1860
Query: 1861 AGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEG 1920
AGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEG
Sbjct: 1861 AGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEG 1920
Query: 1921 MVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAA 1980
MVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAA
Sbjct: 1921 MVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAA 1980
Query: 1981 REGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGPHGLG 2040
REGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGPHGLG
Sbjct: 1981 REGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPPGPHGLG 2040
Query: 2041 PLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGPRGRGKKLTLACPGPLADSSVTLS 2100
PLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGPRGRGKKLTLACPGPLADSSVTLS
Sbjct: 2041 PLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGPRGRGKKLTLACPGPLADSSVTLS 2100
Query: 2101 PVDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSL 2160
PVDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSL
Sbjct: 2101 PVDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLSL 2160
Query: 2161 GLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPGHGEE 2220
GLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPGHGEE
Sbjct: 2161 GLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVPGHGEE 2220
Query: 2221 YPAAGAHSSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAM 2280
YPAAGAHSSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAM
Sbjct: 2221 YPAAGAHSSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSESTPSPATATGAM 2280
Query: 2281 ATTTGALPAQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA 2321
ATTTGALPAQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA
Sbjct: 2281 ATTTGALPAQPLPLSVPSSLAQAQTQLGPQPEVTPKRQVLA 2321
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 2486 bits (6443), Expect = 0.0
Identities = 1194/2300 (51%), Positives = 1484/2300 (64%), Gaps = 197/2300 (8%)
Query: 21 PPPVRALPLLLLLAGPGAAAPPCLD-GSPCANGGRCTQLPSREAACLCPPGWVGERCQLE 79
PP + L L LL A P C G C NGG+C EA C+C +VG RCQ
Sbjct: 2 PPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEA-CVCGGAFVGPRCQDP 60
Query: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP------------------- 120
+PC S PC G C G A ++C C GF GP C P
Sbjct: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLL 120
Query: 121 ---------------------DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 159
DPC S+PCA+G +C + + ++C CPP + G +CR DV
Sbjct: 121 TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQC-LPFEASYICHCPPSFHGPTCRQDV 179
Query: 160 DECRVGEP---CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG 216
+EC G+ CRHGGTC N GS+RC C A +TGP CE P VPC+PSPC+NGGTCR +G
Sbjct: 180 NEC--GQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTG 237
Query: 217 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 276
D+T++CACLPGF GQNCE N+DDCPG+ C NGG CVDGVNTYNC+CPPEWTGQ+CTEDVD
Sbjct: 238 DVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVD 297
Query: 277 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASF 336
ECQL PNAC NGGTC NT GG++CVCVNGWTGE CS+NIDDCA+A CFHGATCHDRVASF
Sbjct: 298 ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASF 357
Query: 337 YCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECS 396
YC CP G+TGLLCHL+DAC+SNPC+E + CDTNPVNG+AICTCP G+TG AC QDVDECS
Sbjct: 358 YCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECS 417
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCI 456
+GANPCEH G+C+NT GSF CQC +GYTGPRCE DVNEC+S PC+N ATCLD+IG+F CI
Sbjct: 418 LGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCI 477
Query: 457 CMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
CM G+ G +CEV+ DEC SSPC++ G C D++N F C CP+GF+G CQ DVDECASTPC
Sbjct: 478 CMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPC 537
Query: 517 RNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTG 576
+NGAKC+D P+ Y C C EG+ GT C+ ++D+C PDPCH+G C DG+A+F+C C PGYTG
Sbjct: 538 KNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTG 597
Query: 577 TRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRD 636
CE+ ++EC SQPCRHGG C D + YLC C GTTG NCE+N+DDCAS+PC G C D
Sbjct: 598 HHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLD 657
Query: 637 GINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS 696
I+ Y+C C+PG+TG +CN+ I+ECA +PC GG+C DG NGF C CP G P CL
Sbjct: 658 KIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEV 717
Query: 697 HPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGF 756
+ C PC HG C D+ G++C C+PGWSG C + + CES PC GGTC G+
Sbjct: 718 NECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC--DINNNECESNPCVNGGTCKDMTSGY 775
Query: 757 HCTCPPGVQGRQCE---------------------------------------LLSPCTP 777
CTC G G C+ +L+PC P
Sbjct: 776 VCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAP 835
Query: 778 NPCEHGGRC-ESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCT 836
+PC +GG C +S + C CP GWQG C+ D++EC +PC C N G + C
Sbjct: 836 SPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECV-LSPCRHGASCQNTHGGYRCH 894
Query: 837 CHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC 896
C GY+G +C+ DI+DC PNPC NGGSC DG+ + C CLPGF G C D++EC S+PC
Sbjct: 895 CQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPC 954
Query: 897 GPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYT 955
G CTD V S+TCTCP G+ G HCE + PDC+ SSCFNGGTCVDG+NSF+CLC PG+T
Sbjct: 955 RNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFT 1014
Query: 956 GAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC 1015
G++CQH+ + C S+PCLHGG C +RCTC + +TGP CQ LV WC PC+NGG+C
Sbjct: 1015 GSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKC 1074
Query: 1016 VQTGAY--CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCP 1073
QT C CP GW+G CD+ S+ C AA + GV + +LCQ GG CVD ++H+C C
Sbjct: 1075 WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQ 1134
Query: 1074 EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQH 1133
G TGS+CE VD C PCQ+G TC Y+GGY C+C+ GY+G NC +++DEC S PCQ+
Sbjct: 1135 AGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQN 1194
Query: 1134 GGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPG-PPLDSGPRCLHNGTCVDLVGGFRCT 1192
GG+C+DL Y CSCP GT GV CEIN DDC P P+ P+C +NGTCVD VGG+ CT
Sbjct: 1195 GGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCT 1254
Query: 1193 CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
CPPG+ G RCE D+NEC S C A T++C+Q F C C AG +G RC++V++ C+
Sbjct: 1255 CPPGFVGERCEGDVNECLSNPCDARGTQNCVQRV-NDFHCECRAGHTGRRCESVINGCKG 1313
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
+PC++GG C + G F C C F G CE AR+C L+C G C PR P
Sbjct: 1314 KPCKNGGTCAVASNTARG--FICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPT 1371
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372
C C +GP C+ FP S P PC + G+C P +PF+RC C + G C
Sbjct: 1372 CLCLGPFTGPECQ-FPASSP-----CLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425
Query: 1373 E---------APAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGD 1423
A P E C CQ G++ C +CN+ CGWDGGDCSL+ D
Sbjct: 1426 HILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFND 1485
Query: 1424 PWRQC-EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADG 1482
PW+ C ++LQCW+ F++ CD C+S CL+D FDC E CNP+Y++YC DHF+DG
Sbjct: 1486 PWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRA--EGQCNPLYDQYCKDHFSDG 1543
Query: 1483 RCDQGCNTEECGWDGLDCASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTS 1542
CDQGCN+ EC WDGLDCA VP LA G LV+ VL+PPE+L SS FL+ LS +L T+
Sbjct: 1544 HCDQGCNSAECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTN 1603
Query: 1543 LRFRLDAHGQAMVFPYH------RPSP-------------------------GSE-PRAR 1570
+ F+ DAHGQ M+FPY+ R P GSE R R
Sbjct: 1604 VVFKRDAHGQQMIFPYYGREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRR 1663
Query: 1571 RELAP-EVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADYLGALSAVERLDFPYPLRDV 1629
REL P +V GS+V LEIDNR C+Q+ + CF A A +LGAL+++ L+ PY + V
Sbjct: 1664 RELDPMDVRGSIVYLEIDNRQCVQA--SSQCFQSATDVAAFLGALASLGSLNIPYKIEAV 1721
Query: 1630 RGEPLEPPEPSVPLLPLLVAGAVLLLVILVLGVMVAR-RKREHSTLWFPEGFSLHKDVAS 1688
+ E +EPP P+ + A A +LL + GV+++R R+R+H LWFPEGF + + +
Sbjct: 1722 QSETVEPPPPAQLHFMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSE---A 1778
Query: 1689 GHKGRREPVGQDALGMKNM--AKGESLMGEVATDWMDTECPEAKRLKVEEPGM--GAEEA 1744
K RREP+G+D++G+K + A +LM + +W D + E K+ + EEP + ++
Sbjct: 1779 SKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDL-ETKKFRFEEPVVLPDLDDQ 1837
Query: 1745 VDCRQWTQHHLVAADIRVAPAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCGGALE 1804
D RQWTQ HL AAD+R++ AMA TPPQG+ DAD MDVNVRGPDGFTPLM+AS GG LE
Sbjct: 1838 TDHRQWTQQHLDAADLRMS-AMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLE 1896
Query: 1805 PMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGAD 1864
+EE+E + ++ISD I QGA L +TDRTGETALHLAARY+R+DAAKRLL+A AD
Sbjct: 1897 TGNSEEEE---DAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASAD 1953
Query: 1865 TNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEE 1924
N QD+ GRTPLH AV+ADAQGVFQILIRNR+TDLDARM DG+T LILAARLAVEGM+E+
Sbjct: 1954 ANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLED 2013
Query: 1925 LIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGS 1984
LI SHADVNAVD+LGKSALHWAAAVNNV+A + LLKNGANKDMQ+++EETPLFLAAREGS
Sbjct: 2014 LINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNREETPLFLAAREGS 2073
Query: 1985 YEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGPRSPP-------GPH 2037
YE AK+LLDHFANR+ITDH+DRLPRD+AQER+H DIVRLLD+ + RSP G
Sbjct: 2074 YETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTP 2133
Query: 2038 GLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGPRGRG----KKLTLACPGPLA 2093
L P LC P +L LK G KK R+P K GL + +K + G L
Sbjct: 2134 TLSPPLCSPNGYLGSLKPGVQG-KKVRKPSSK-GLACGSKEAKDLKARRKKSQDGKGCLL 2191
Query: 2094 DSSVTLSPVDSLDSPRPF----GGPPASPGGF------PLE----------GPYAAATAT 2133
DSS LSPVDSL+SP + PP P F PL G A
Sbjct: 2192 DSSGMLSPVDSLESPHGYLSDVASPPLLPSPFQQSPSVPLNHLPGMPDTHLGIGHLNVAA 2251
Query: 2134 AVSLAQLGGPGRAGLGRQPP 2153
+A LGG GR PP
Sbjct: 2252 KPEMAALGGGGRLAFETGPP 2271
Score = 83.6 bits (205), Expect = 2e-15
Identities = 161/616 (26%), Positives = 232/616 (37%), Gaps = 120/616 (19%)
Query: 1757 AADIRVAPAMALTPPQG--DADADGM----------DVNVRGPDGFTPLMLASFCGGALE 1804
+AD + M TP ADA G+ D++ R DG TPL+LA+ A+E
Sbjct: 1951 SADANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARL--AVE 2008
Query: 1805 PMPTEEDEADDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGAD 1864
M + DLI A + A D G++ALH AA DAA LL GA+
Sbjct: 2009 GM--------------LEDLINSHADVNA-VDDLGKSALHWAAAVNNVDAAVVLLKNGAN 2053
Query: 1865 TNAQDHSGRTPLHTAVTADAQGVFQILIRN-RSTDLDARMADGSTALILAARLAVEGMVE 1923
+ Q++ TPL A + ++L+ + + D+ M L +A E M
Sbjct: 2054 KDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDR------LPRDIAQERMHH 2107
Query: 1924 ELIASHADVNAV--DELGKSALHWAAAVN----NVEATLALLKNG---------ANKDMQ 1968
+++ + N V +L + L ++ + L LK G ++K +
Sbjct: 2108 DIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRKPSSKGLA 2167
Query: 1969 DSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDR---LPRDVAQERL------HQD 2019
+E A R+ S + LLD D L+ DVA L
Sbjct: 2168 CGSKEAKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPSPFQQSP 2227
Query: 2020 IVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPG--LKAAQSGSKKSRRPPGKAGLGPQGP 2077
V L P P + G L P A L G A ++G + P +G
Sbjct: 2228 SVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLG 2287
Query: 2078 RGRGKKLTLACPGP--LADSSVTLSPVDSLDSPRPFGGPPAS--PGGFPLEGP------- 2126
G L G L LS + S P + S PG + P
Sbjct: 2288 SSSGGALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMV 2347
Query: 2127 ---YAAATATAVS-LAQLGGPGRAGLGRQP---------PGGCVLSLGLLNPVAVPLDWA 2173
+++ A+A+S + G L QP P + L P + +
Sbjct: 2348 GPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQS 2407
Query: 2174 RLPPPAPPGP--------------SFLL--PLAPGPQLLNPGT----PVSPQERP----- 2208
PPP PP P SFL P Q L P + + PQE P
Sbjct: 2408 LQPPPPPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTS 2467
Query: 2209 -PPYLAVPGHGEEY---PAAGAHSSP---PKARFLRVPSEHPYLTPSPESPEHWASPSPP 2261
P L P ++ P+ ++SSP + L+VP EHP+LTPSPESP+ W+S SP
Sbjct: 2468 LPSSLVPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVP-EHPFLTPSPESPDQWSSSSPH 2526
Query: 2262 S-LSDWSESTPSPATA 2276
S +SDWSE SP T+
Sbjct: 2527 SNVSDWSEGVSSPPTS 2542
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 2469 bits (6398), Expect = 0.0
Identities = 1214/2488 (48%), Positives = 1526/2488 (61%), Gaps = 277/2488 (11%)
Query: 17 PPPPPPPVRALPLLLLLAGPGAAAPPCLDG-SPCANGGRCTQLPSREAACLCPPGWVGER 75
P P + AL L L A A C DG PC N G C + C CP G++GE
Sbjct: 2 PALRPALLWALLALWLCCAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEY 61
Query: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTAR-------------------------------- 103
CQ DPC C G C + + G A
Sbjct: 62 CQHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTC 121
Query: 104 -------FSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
+ C C GF G +C D CLS PCA+G+ C+ + +F C C G+ G+ C
Sbjct: 122 HMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN-QFSCKCLTGFTGQKCE 180
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG 216
+DV+EC + C+HGGTCLN PGS++CQCP G+TG C++ VPCAPSPC NGGTCRQ+G
Sbjct: 181 TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTG 240
Query: 217 DLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 276
D T++C CLPGFEG CE N+DDCP HRC NGG CVDGVNTYNC+CPP+WTGQFCTEDVD
Sbjct: 241 DFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVD 300
Query: 277 ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASF 336
EC LQPNAC NGGTC N GG+ CVCVNGW+G+ CS+NIDDCA A C G+TC DRVASF
Sbjct: 301 ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASF 360
Query: 337 YCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECS 396
C CP GK GLLCHLDDAC+SNPCH+ A+CDTNP+NG+ ICTCP G+ G C +DVDEC+
Sbjct: 361 SCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECA 420
Query: 397 IG-ANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
+ +NPCEH G+CVNT G+F C+C +GY GPRCE D+NEC S PC+N ATCLD+IG FTC
Sbjct: 421 MANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTC 480
Query: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP 515
+CM GF G +CE++I+ECQS+PCVN G C D+VN F C CP GF+G CQ+D+D+C+STP
Sbjct: 481 LCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTP 540
Query: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYT 575
C NGAKC+D P+GYEC+CA GF G LC+ N+D+C PDPCHHG+C DGI S++C C PGY
Sbjct: 541 CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYM 600
Query: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR 635
G C Q+DEC S PC + G+C+DLV+ Y C C GT+GVNCE+N DDCASNPC G+C
Sbjct: 601 GAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICM 660
Query: 636 DGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPP 695
DGINRY CVC PGFTG CN++I+ECAS+PC +G +C++G NGFRC+CP G P C
Sbjct: 661 DGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720
Query: 696 SHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 755
+ C PC HG C G++C+C+ GW G C + ++ C S PC+ GGTC + G
Sbjct: 721 VNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCE--VDKNECLSNPCQNGGTCDNLVNG 778
Query: 756 FHCTCPPGVQGRQCEL---------------------------------------LSPCT 776
+ CTC G +G C++ L+PC+
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
Query: 777 PNPCEHGGRCESAPG-QLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC 835
PNPCE+ C+ +P + C C GWQG RC D+DEC PC HG+C N GS+ C
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISK-PCMNHGLCHNTQGSYMC 897
Query: 836 TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNP 895
C G++G C++DI+DC NPC NGGSC DGV +FSC CLPGF G +C D++ECLS P
Sbjct: 898 ECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEP 957
Query: 896 C-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
C GTC+D+V S+TC C G+ G HCE ++ +C+ SSCFNGGTCVDG+NSFSCLC G+
Sbjct: 958 CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGF 1017
Query: 955 TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGR 1014
TG+ C HE + C S PCL+ G C +RC+C +TG CQTLV+ CSR PC+N G
Sbjct: 1018 TGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGT 1077
Query: 1015 CVQTGA--YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC 1072
CVQ A CLCP GW+G CD+ ++ C AA++ GV +E LCQ G C++ ++HYC C
Sbjct: 1078 CVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQC 1137
Query: 1073 PEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQ 1132
P G TGS+CE+++D C + PCQHG TC ++GGY CEC+PGY G NCE +VDEC +QPCQ
Sbjct: 1138 PLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQ 1197
Query: 1133 HGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT 1192
+GG+CIDLV + CSCPPGT G+LCE N DDC GP CL+ G C+D +GG+ C
Sbjct: 1198 NGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCA------RGPHCLNGGQCMDRIGGYSCR 1251
Query: 1193 CPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
C PG+ G RCE DINEC S C + + DC+Q + C+C + F+G C+T + C
Sbjct: 1252 CLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCPQ 1310
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
PC +GG C + G F C C F G RC+ SC +++C G C T GPR
Sbjct: 1311 MPCLNGGTCAVASNMPDG--FICRCPPGFSGARCQS---SCGQVKCRKGEQCVHTASGPR 1365
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372
C CP P + CA++PC HGGSC P P++ C CA ++G RC
Sbjct: 1366 CFCPS--------------PRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRC 1411
Query: 1373 EAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA-L 1431
E A P + C C K D CD CNS C WDGGDCSL++ +PW C + L
Sbjct: 1412 ELYTAPPS-TPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Query: 1432 QCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTE 1491
CW NN +CD C++ CL+DNF+C G +TC Y+KYCADHF D CDQGCN+E
Sbjct: 1471 PCWDYINN-QCDELCNTVECLFDNFECQ--GNSKTCK--YDKYCADHFKDNHCDQGCNSE 1525
Query: 1492 ECGWDGLDCASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHG 1551
ECGWDGLDCA++ P LA G LV+ VL+PPE+LL+ + FL+ L +L T+LR + D+ G
Sbjct: 1526 ECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDARSFLRALGTLLHTNLRIKRDSQG 1585
Query: 1552 QAMVFPYHRPSPGSEPRARR-------ELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDA 1604
+ MV+PY+ + + R E EV GS V LEIDNR C+Q ++DHCF +
Sbjct: 1586 ELMVYPYYGEKSAAMKKQRMTRRSLPGEQEQEVAGSKVFLEIDNRQCVQ--DSDHCFKNT 1643
Query: 1605 QSAADYLGALSAVERLDFPYPLRDVRGEPLEPPEPSVPLLPLLVAGAVLLLVILVLGVMV 1664
+AA L + + L YPL V E L P LL LL V++L I++LGV++
Sbjct: 1644 DAAAALLASHAIQGTLS--YPLVSVVSESLTPERTQ--LLYLLAVAVVIILFIILLGVIM 1699
Query: 1665 ARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMKNMAKGESLMGEVATD---- 1720
A+RKR+H +LW PEGF+L +D AS HK RREPVGQDA+G+KN++ S + T
Sbjct: 1700 AKRKRKHGSLWLPEGFTLRRD-ASNHK-RREPVGQDAVGLKNLSVQVSEANLIGTGTSEH 1757
Query: 1721 WMDTECPEAKRLKVEEPGMGAEE--AVDCRQWTQHHLVAADIRVAPAMALTPPQGDADAD 1778
W+D E P+ K++K E+ + +EE +D R WTQ HL AADIR P++ALTPPQ + + D
Sbjct: 1758 WVDDEGPQPKKVKAEDEALLSEEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVD 1817
Query: 1779 GMDVNVRGPDGFTPLMLASFCGGALEPMPTEEDEADDTSASIISDLICQGAQLGARTDRT 1838
+DVNVRGPDG TPLMLAS GG+ + + E+++A+D+SA+II+DL+ QGA L A+TDRT
Sbjct: 1818 VLDVNVRGPDGCTPLMLASLRGGSSD-LSDEDEDAEDSSANIITDLVYQGASLQAQTDRT 1876
Query: 1839 GETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTD 1898
GE ALHLAARY+RADAAKRLLDAGAD NAQD+ GR PLH AV ADAQGVFQILIRNR TD
Sbjct: 1877 GEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTD 1936
Query: 1899 LDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLAL 1958
LDARM DG+T LILAARLAVEGMV ELI ADVNAVD+ GKSALHWAAAVNNVEATL L
Sbjct: 1937 LDARMNDGTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLL 1996
Query: 1959 LKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQ 2018
LKNGAN+DMQD+KEETPLFLAAREGSYEAAK+LLDHFANR+ITDH+DRLPRDVA++R+H
Sbjct: 1997 LKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHH 2056
Query: 2019 DIVRLLDQPSGPRSPPGP---HGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQ 2075
DIVRLLD+ + SPPG L P++C P LK G KKSRRP K+ +
Sbjct: 2057 DIVRLLDEYNVTPSPPGTVLTSALSPVICGPNRSFLSLKHTPMG-KKSRRPSAKSTMPTS 2115
Query: 2076 GP---------RGRGKKLTLACPGPLADSSVTLSPVDSLDSPRPF-------------GG 2113
P +G +K +L+ L++SSVTLSPVDSL+SP + G
Sbjct: 2116 LPNLAKEAKDAKGSRRKKSLSEKVQLSESSVTLSPVDSLESPHTYVSDTTSSPMITSPGI 2175
Query: 2114 PPASPGGF--------PLEGPYAAATATAVSLAQLGGPGRAGLGR-----------QPPG 2154
ASP P+ +A + + + L L P
Sbjct: 2176 LQASPNPMLATAAPPAPVHAQHALSFSNLHEMQPLAHGASTVLPSVSQLLSHHHIVSPGS 2235
Query: 2155 GCVLSLGLLNPVAVPLDW--------------------------------ARLP------ 2176
G SL L+PV VP DW +R P
Sbjct: 2236 GSAGSLSRLHPVPVPADWMNRMEVNETQYNEMFGMVLAPAEGTHPGIAPQSRPPEGKHIT 2295
Query: 2177 -PPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPYLAVP-------------------- 2215
P P P L P + P PQ PP +A P
Sbjct: 2296 TPREPLPPIVTFQLIPKGSIAQPAGAPQPQSTCPPAVAGPLPTMYQIPEMARLPSVAFPT 2355
Query: 2216 -------GHGEEYPAAGAHSSPPK-ARFLRVPSEHPYL-------TPS------------ 2248
G + H P ++ PS+H Y TPS
Sbjct: 2356 AMMPQQDGQVAQTILPAYHPFPASVGKYPTPPSQHSYASSNAAERTPSHSGHLQGEHPYL 2415
Query: 2249 ---PESPEHWASPSPPSLSDWSESTPSP 2273
PESP+ W+S SP S SDWS+ T SP
Sbjct: 2416 TPSPESPDQWSSSSPHSASDWSDVTTSP 2443
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 1173 bits (3034), Expect = 0.0
Identities = 726/1981 (36%), Positives = 958/1981 (48%), Gaps = 241/1981 (12%)
Query: 278 CQLQPNACHNGGTCFN-TLGGHSCVCVNGWTGESCSQNIDDCATA-VCFHGATCHDRVAS 335
C P C NGGTC + +LG +C C G+ GE+C Q D C A +C +G +C + +
Sbjct: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQNAQLCQNGGSCQALLPA 86
Query: 336 FYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDEC 395
P+G S+P +P+ +CTC PGFTG C +++
Sbjct: 87 -----PLGLP-----------SSP---------SPLTPSFLCTCLPGFTGERCQAKLED- 120
Query: 396 SIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFT 454
+ C GRC + G C C G+TG +C+ + C + PC N CL Q
Sbjct: 121 PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQ 179
Query: 455 CICMAGFTGTYCEVDIDEC--QSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECA 512
C C GF G CE D++EC PC G C + + F C CP G G C+L C
Sbjct: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCP 239
Query: 513 STPCRNGAKCVDQPDG----YECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFS 567
C NG C P+ + C C GF G C+ N D+C C +G C DG+ +++
Sbjct: 240 PRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYT 299
Query: 568 CACAPGYTGTRCESQVDECRSQP---CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC 624
C C +TG C VDEC +Q CR+GG C + + C C SG G +CE N+DDC
Sbjct: 300 CLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
Query: 625 ASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGE--NGFRC 681
+ C G C D + + C+C PG TG LC++E + C S PC C C
Sbjct: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLC 418
Query: 682 LCPPGSLPPLCLPPSHPC-----AHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
LC PG P C C PC HG C + PG F C+C PG++G RC
Sbjct: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEAD--H 476
Query: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLP 794
+ C SQPC G TC FHC CPPG++G+ CE+ + C PC + C
Sbjct: 477 NECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
Query: 795 VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
C C G+ G RC++D+DEC +PC G C + G+F C C G+ GP C ++++C
Sbjct: 537 -CICLPGFSGTRCEEDIDECRS-SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL 594
Query: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAG-----PRCA-------------RDVDECLSNPC 896
+PC G SC D G+F C C GF G P CA +D CL
Sbjct: 595 SDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
Query: 897 GPG------TCT---DHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS 947
PG CT H +C C G+ G CE +L C + C +GGTC + ++
Sbjct: 655 SPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYN 714
Query: 948 CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ 1007
C C GYTG C E C S PCL+GG C+ + G+ CTC S TGPQCQT D+C
Sbjct: 715 CTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 1008 PCQNGGRCV-QTGAY-CLCPPGWSGRLCDIR------SLPCREAAA-------------- 1045
PC NGG CV + G + CLC G+ G C+ + PCR A
Sbjct: 775 PCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPT 834
Query: 1046 ---------QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC-------- 1088
+ + ++ C C+ S +C+C +G TG C + C
Sbjct: 835 GYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 1089 --LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1146
++ C +GG C Y C C PG+ G C+D V+ C S+PCQ+G +C+ + YLC
Sbjct: 895 IDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLC 954
Query: 1147 SCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADI 1206
C PG G C D C P C ++GTC GGF C CPPG+ GLRCE D+
Sbjct: 955 QCAPGYDGQNCSKELDACQSQP-------CHNHGTCTPKPGGFHCACPPGFVGLRCEGDV 1007
Query: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPG 1266
+EC CH T C F C C G +G C+ + PC SQPC HGG C + G
Sbjct: 1008 DECLDQPCHPTGTAAC-HSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAG 1066
Query: 1267 PGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRG---PRCACPPGLSGPS 1323
L F CHC + F GP C A SC C G C +P+ PRCAC G GP
Sbjct: 1067 --SPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPD 1124
Query: 1324 CRSFPGSPPGASNASCAAAPCLHGGSCRPAPL--APFFRCACAQGWTGPRCEAPAAAPEV 1381
C + P +P G S PCL+ GSC P FRC+C GPRC+ P A
Sbjct: 1125 CLT-PPAPKGCGPPS----PCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAK--- 1176
Query: 1382 SEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA-LQCWRLFNNS 1440
C+ + GD CD C+ PG WDGGDCSL V DPW+ C + +CW LF +
Sbjct: 1177 ---------GCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227
Query: 1441 RCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDC 1500
+C P C S CL+D +DC C P Y++YC DHF +G C++GCNT ECGWDG DC
Sbjct: 1228 QCHPQCDSEECLFDGYDCET---PPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDC 1284
Query: 1501 ASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAHGQAMVFPYHR 1560
E L L V+L P L + + LS LR L R D G+ MV+PY
Sbjct: 1285 RPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPY-- 1342
Query: 1561 PSPGS----------EPRARRELAPEV-----------IGSVVMLEIDNRLCLQSPENDH 1599
PG+ +P + AP+ G VV++ +D C
Sbjct: 1343 --PGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAGFVVVMGVDLSRCGPDHPASR 1400
Query: 1600 CFPDAQSAADYLGALSAVERLD--FPYPLRDVRGEP-LEPPEPSVPLLPLL---VAGAVL 1653
C D +L A++AV L+ P PL V PP +P P+L VAG +L
Sbjct: 1401 CPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPW-PVLCSPVAGVIL 1459
Query: 1654 L-LVILVLGVMVARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMKNMAKGES 1712
L L L++ ++ RR+REH LW P GF+ S RR P+G+D++G+K +
Sbjct: 1460 LALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKP--- 1516
Query: 1713 LMGEVATDWMDTECPEAKRLKVEEPGMGAEEAVD--CRQWTQHHLVAADIRVAPAMALTP 1770
EV D + C + + EE G E C+ W+ A + A LTP
Sbjct: 1517 -KAEVDEDGV-VMCSGPE--EGEEVGQAEETGPPSTCQLWSLSGGCGA---LPQAAMLTP 1569
Query: 1771 PQGDADADGMDVNVRGPDGFTPLMLASFCG----GALE------PMPTEEDEADDTSASI 1820
PQ +++ + D++ RGPDG TPLM A CG G + P P E
Sbjct: 1570 PQ-ESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEP---------- 1618
Query: 1821 ISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAV 1880
L+ GA A T TGET LHLAAR++R AA+RLL+AGA+ N D +GRTPLH AV
Sbjct: 1619 ---LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAV 1675
Query: 1881 TADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVDELGK 1940
ADA+ V Q+L+R+R T +DAR DG+T L+LAARLAVE +VEELIA+ ADV A D+ GK
Sbjct: 1676 AADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGK 1735
Query: 1941 SALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANREI 2000
+ALHWAAAVNN A +LL+ GA+KD QD++E+TPLFLAAREG+ E A+LLL A RE+
Sbjct: 1736 TALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAAREL 1795
Query: 2001 TDHLDRLPRDVAQERLHQDIVRLLDQPSGP----RSPPGPHGLGPLLCPPGAFLPGLKAA 2056
D P DVA +R H D++ LL+ P ++ PG GP P +
Sbjct: 1796 RDQAGLAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREA-GPF--PRARTVSVSVPP 1852
Query: 2057 QSGSKKSRRPPGKAGLGPQGP----RGRGKKLTLACPGPLADSSV-TLSPVDSLDSPRPF 2111
G R AG GP+G + R + LA G A S +LS V + P P
Sbjct: 1853 HGGGALPRCRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPR 1912
Query: 2112 G 2112
G
Sbjct: 1913 G 1913
Score = 968 bits (2502), Expect = 0.0
Identities = 523/1301 (40%), Positives = 650/1301 (49%), Gaps = 130/1301 (9%)
Query: 42 PCLDGSPCANGGRCTQL-------PSREAA------CLCPPGWVGERCQ--LEDPCHSGP 86
PC + C NGG C L PS + C C PG+ GERCQ LEDPC
Sbjct: 67 PCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF 126
Query: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
C+ RG C + + R C C G+ G C L D C ++PC +G C + + C C
Sbjct: 127 CSKRGRCH---IQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVC-LATYPQIQCHC 182
Query: 147 PPGYQGRSCRSDVDEC-RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSP 205
PPG++G +C DV+EC + PC G +C NT GSF+C CP G GP CE A PC P
Sbjct: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
Query: 206 CRNGGTCR--QSGDLTYD-CACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
C NGGTC+ D T+ C C PGF G +CEVN D+C H+C NGGTC DG++TY C C
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
Query: 263 PPEWTGQFCTEDVDECQLQ-PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATA 321
P WTG C+EDVDEC+ Q P C NGGTC N+ G CVCV+GW G SC +N+DDC A
Sbjct: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
Query: 322 VCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPP 381
C G+TC DRV SF C CP G+TGLLCHL+D C+S PCH DA C TNP+ G +C C P
Sbjct: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQP 422
Query: 382 GFTGGACDQDVDECSI---GANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG 438
G++G C QD+DEC + G +PCEH G C+NT GSF C C GYTG RCE D NECLS
Sbjct: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
Query: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG 498
PC +TCLD + F C+C G G CEV+ +EC S+PC+N C D +NGF C C G
Sbjct: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
Query: 499 FSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG- 557
FSG+ C+ D+DEC S+PC NG +C DQP + C+C GFEG C VD+C DPC G
Sbjct: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA 602
Query: 558 RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 617
C+D +F C C G+TG CE V C C+ C D DK C CP G+ G C
Sbjct: 603 SCLDLPGAFFCLCPSGFTGQLCE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--C 658
Query: 618 EVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
D+C C G C+ R CVC G+TGP C E+ C S+PC GG+C +
Sbjct: 659 APPEDNCT---CHHGHCQ----RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
Query: 678 GFRCLCPPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARD 736
G+ C CP G P C C PC + G C +PGG+ C C P +GP+C S D
Sbjct: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTS--TD 769
Query: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE--LLSPCTPNPCEHGGRCESAPGQLP 794
C S PC GGTC + F C C G QG +CE L C +PC + C+ +P Q P
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSP-QGP 828
Query: 795 VCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
C CP G+ G CQ +D CA PC + C SF C C G+TGP C+ ++ C
Sbjct: 829 RCLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQ 887
Query: 855 ----------PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTD 903
+ C NGG C D S+ C C PGF G C V+ C S PC G TC
Sbjct: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947
Query: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA 963
+ + C C PGY G +C ++L C C N GTC F C C PG+ G C+ +
Sbjct: 948 QPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDV 1007
Query: 964 DPCLSRPCLHGG--VCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--- 1018
D CL +PC G C + F C CL TG C+ +D C QPC +GG C T
Sbjct: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGS 1067
Query: 1019 --GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY---CVCP 1073
G C CP G+ G C R+ C C GG C+ + C C
Sbjct: 1068 PLGFICHCPKGFEGPTCSHRAPSCG----------FHHCHHGGLCLPSPKPGFPPRCACL 1117
Query: 1074 EGRTGSHCEQEVDP--C-LAQPCQHGGTCRGYMG----GYMCECLPGYNGDNCEDDVDEC 1126
G G C P C PC + G+C G G+ C C G C+ +
Sbjct: 1118 SGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ----KP 1173
Query: 1127 ASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLV 1186
++ C+ G D CS P G + DC G P D C + C L
Sbjct: 1174 GAKGCE--GRSGDGACDAGCSGPGGNW------DGGDCSLGVP-DPWKGCPSHSRCWLL- 1223
Query: 1187 GGFR-CTCPPGYTGLRCEADINECRS-GACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQ 1244
FR C P C D +C + AC A+ + CH F C+
Sbjct: 1224 --FRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQ------------YCHDHFHNGHCE 1269
Query: 1245 TVLSPCESQPC-QHGGQCRPSPGPGGGLTFTCHCAQPFWGP 1284
C + C GG CRP G P WGP
Sbjct: 1270 ---KGCNTAECGWDGGDCRPEDG------------DPEWGP 1295
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 530 bits (1366), Expect = e-150
Identities = 321/1060 (30%), Positives = 462/1060 (43%), Gaps = 169/1060 (15%)
Query: 49 CANGGRC-TQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTAR-FSC 106
C+ G+C ++ S+ +C C P + G+ CQ D C PC G C + + + C
Sbjct: 183 CSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYEC 242
Query: 107 RCPRGFRGPDCS-LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDEC--- 162
C F G +CS + C C HG CS F+C C + G C C
Sbjct: 243 VCHPPFTGKNCSEIIGQCQPHVCFHG-NCSNITSNSFICECDEQFSGPFCEVSAKPCVSL 301
Query: 163 -------------------------RVGE---------PCRHGGTCLNTPGSFRCQCPAG 188
+ GE PC++G C+ C C
Sbjct: 302 LFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPI 361
Query: 189 YTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP--GHRCL 246
+T LC++ C P RN TC++ + Y C+C+ GF +NCE +D C CL
Sbjct: 362 FTDLLCKSIQTSCESFPLRNNATCKKC-EKDYPCSCISGFTEKNCEKAIDHCKLLSINCL 420
Query: 247 NGG-----------TCVDG--------------VNTYNCQC------------PPE---- 265
N C+ G ++ + C C P +
Sbjct: 421 NEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYV 480
Query: 266 WTGQFCTEDVDECQ--------LQPNACH----------NGGTCFNTLGGHSCVCVNG-- 305
W F + ++CQ L N N +C+ G +C NG
Sbjct: 481 WQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCS 540
Query: 306 -----------------WTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLL 348
W G +N D C H A C D + C+C + G L
Sbjct: 541 CLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRL 600
Query: 349 CHLD-DACVSN---PCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEH 404
C ++ D C+ N H + ++ N C+ + C+ D ++C + C++
Sbjct: 601 CVVNVDYCLGNHSISVHGLCLALSHNCN----CSGLQRYERNICEIDTEDCKSAS--CKN 654
Query: 405 LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ------------ 452
+ +G F +C G+ G +CE D++EC S PC+N ATC+D+ G
Sbjct: 655 GTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVV 714
Query: 453 --FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDE 510
F+C+C G+ G CE DID+C + C + CKD + C C S + G+ C+ + +E
Sbjct: 715 DGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNE 774
Query: 511 CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR-CVDGI--ASFS 567
C PC+N + C D Y C C G+ G C +++C DPC +G C + F
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
Query: 568 CACAPGYTGTRCESQVDECR--SQPCRHGGKCLDLVD-KYLCRCPSGTTGVNCEVNIDDC 624
C C P YTG C + + C PCR+ CL LVD C C G NCE+++ DC
Sbjct: 835 CLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDC 894
Query: 625 ASNPCT-FGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLC 683
C +G C D +N + C+C+PGF+G LC +EINEC+S PC G+CVD N F C C
Sbjct: 895 LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNC 954
Query: 684 PPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP 742
P P C + C PC C G+ C+C PG++G C +L D C S+P
Sbjct: 955 EPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINL--DECLSEP 1012
Query: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQG 801
C G C + C C G G CE + C NPC HG RC + P CSC
Sbjct: 1013 CLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEYP-CSCDAD 1070
Query: 802 WQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDC-DPNP--- 857
+C+ +++C PC G C A F+C C GYTG C++ I++C +P
Sbjct: 1071 GTSTQCKIKINDCTS-IPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSV 1129
Query: 858 -CLNGGSCQDGVG-SFSCSCLPGFAGPRCARDVDECLSNPCGPGT-CTDHVASFTCTCPP 914
CLNGG C DG G +F C CLPGF+G C +++EC S+PC G C DH+ + C C P
Sbjct: 1130 ICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQP 1189
Query: 915 GYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
G+ G HCE +L +C P+SC + C++ +CLC PG+
Sbjct: 1190 GWSGHHCENEL-ECIPNSCVHE-LCMENEPGSTCLCTPGF 1227
Score = 517 bits (1332), Expect = e-146
Identities = 342/1097 (31%), Positives = 465/1097 (42%), Gaps = 169/1097 (15%)
Query: 240 CPGHRCLNGGTCVDGV--NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGG 297
C GH G C+ TY+C C P ++G++C E +D C +P C N G+C N
Sbjct: 183 CSGH-----GKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP--CKNNGSCINKREN 234
Query: 298 -----HSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD 352
+ CVC +TG++CS+ I C VCFHG + SF C C +G C +
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Query: 353 -DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNT 411
CVS + IC + + CP G + + DV E S+ PC++ C+
Sbjct: 295 AKPCVSLLFWKRGICPNS--SSAYTYECPKGSSSQNGETDVSEFSLV--PCQNGTDCIKI 350
Query: 412 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 471
+C C +T C++ C S P RN ATC + C C++GFT CE ID
Sbjct: 351 SNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID 410
Query: 472 E----------------------------CQSSPC------------------VNGGVCK 485
C +PC G+C+
Sbjct: 411 HCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQ 470
Query: 486 DRVNG-FSCTCPSGFSGST---CQLDVD------------------------------EC 511
D+ F GF+GS CQ +D E
Sbjct: 471 DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEG 530
Query: 512 ASTPCRNGAKCVDQPDGYECR--CAEGFEGTLCDRNVDDCSPDPCHHGR-CVDGIASFSC 568
C NG C+ + D E R C + G + N D + C H C D I C
Sbjct: 531 TKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRC 590
Query: 569 ACAPGYTGTRCESQVDECR-SQPCRHGGKCLDLVDKYLCRCPSGTTGVN---CEVNIDDC 624
+C+ Y G C VD C + G CL L + C C SG CE++ +DC
Sbjct: 591 SCSLSYIGRLCVVNVDYCLGNHSISVHGLCLAL--SHNCNC-SGLQRYERNICEIDTEDC 647
Query: 625 ASNPCTFGVCRDGINRYDC-VCQPGFTGPLCNVEINECASSPCGEGGSCVDGE------- 676
S C G + Y C PGF G C ++I+ECAS PC G +C+D
Sbjct: 648 KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQC 707
Query: 677 -------NGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPR 728
+GF CLC PG + C C C H C D ++CVC W G
Sbjct: 708 VPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNF 767
Query: 729 CSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC-ELLSPCTPNPCEHGGRCE 787
C Q + C+ PC+ TC+ + C C G G+ C E ++ C +PC +GG C
Sbjct: 768 CEQE--SNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCH 825
Query: 788 SA--PGQLPVCSCPQGWQGPRCQQDVDEC-AGPAPCGPHGICTNLAGSFS-CTCHGGYTG 843
+ PGQ VC CP + G C Q + C PC + C L + C C + G
Sbjct: 826 ESTIPGQF-VCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEG 884
Query: 844 PSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCT 902
+C+ D+ DC C + G C+D V +F C C PGF+G C +++EC S PC GTC
Sbjct: 885 KNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCV 944
Query: 903 DHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
D F C C P Y G CE D+ C S C + CV + ++CLC PGYTG +C+
Sbjct: 945 DLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEIN 1004
Query: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY 1021
D CLS PCLH GVC + C C F G C+T + C PC +G RC + Y
Sbjct: 1005 LDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHG-RCTELINEY 1063
Query: 1022 -CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH 1080
C C + C I+ C C G C C+CP G TG++
Sbjct: 1064 PCSCDADGTSTQCKIKINDCTSIP----------CMNEGFCQKSAHGFTCICPRGYTGAY 1113
Query: 1081 CEQEVDPCLAQP------CQHGGTCRGYMGG-YMCECLPGYNGDNCEDDVDECASQPCQH 1133
CE+ +D C A+P C +GG C G + C CLPG++G CE +++EC+S PC H
Sbjct: 1114 CEKSIDNC-AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLH 1172
Query: 1134 GGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC 1193
G C D + Y+C C PG G CE NE +C P C+H C++ G C C
Sbjct: 1173 GADCEDHINGYVCKCQPGWSGHHCE-NELECIPNS-------CVHE-LCMENEPGSTCLC 1223
Query: 1194 PPGY----TGLRCEADI 1206
PG+ GL C +I
Sbjct: 1224 TPGFMTCSIGLLCGDEI 1240
Score = 471 bits (1213), Expect = e-132
Identities = 308/1057 (29%), Positives = 428/1057 (40%), Gaps = 189/1057 (17%)
Query: 471 DECQSSPCVNGGVCKDRV--NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG 528
+ S C G C +SC C FSG CQ ++D C+ PC+N C+++ +
Sbjct: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQ-ELDACSFKPCKNNGSCINKREN 234
Query: 529 -----YECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIA-SFSCACAPGYTGTRCESQ 582
YEC C F G C + C P C HG C + + SF C C ++G CE
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS 294
Query: 583 VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRY 641
C S G C + Y CP G++ N E ++ + + PC G C N
Sbjct: 295 AKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDV 354
Query: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPP----------- 690
C+C P FT LC C S P +C E + C C G
Sbjct: 355 MCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKL 414
Query: 691 --------------------LCLPPSHPCAHEPC-------------------SHGICYD 711
+C+P C PC HGIC D
Sbjct: 415 LSINCLNEEWCFNIIGRFKYVCIPG---CTKNPCWFLKNVYLIHQHLCYCGVTFHGICQD 471
Query: 712 -APGGFRCVCEPGWSGPRCSQS---------LARDACES--------------------- 740
P F V + G++G + LA + E
Sbjct: 472 KGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGT 531
Query: 741 -QPCRAGGTCSS--DGMGFHCTCPPGVQGRQ-CELLSPCTPNPCEHGGRCESAPGQLPVC 796
+ C G +C S D + C G E + N C+H C+ + P C
Sbjct: 532 KEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR-PRC 590
Query: 797 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG--GYTGPSCDQDINDCD 854
SC + G C +VD C G HG+C LA S +C C G Y C+ D DC
Sbjct: 591 SCSLSYIGRLCVVNVDYCLGNHSISVHGLC--LALSHNCNCSGLQRYERNICEIDTEDCK 648
Query: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDH--------- 904
C NG + G F C+PGF G +C D+DEC S+PC G TC D
Sbjct: 649 SASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQCV 708
Query: 905 -----VASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHC 959
V F+C C PGY G CEQD+ DC ++C + TC D S+ C+C + G C
Sbjct: 709 PPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFC 768
Query: 960 QHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT- 1018
+ E++ C PC + C+ + +RC C +TG C ++ C PC NGG C ++
Sbjct: 769 EQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHEST 828
Query: 1019 --GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD-EDSSHYCVCPE 1074
G + CLCPP ++G+ C R C L C+ C+ D++ +C+C E
Sbjct: 829 IPGQFVCLCPPLYTGQFCHQRYNLCD--------LLHNPCRNNSTCLALVDANQHCICRE 880
Query: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHG 1134
G +CE +V CL CQ G C + + C C PG++G CE +++EC+S+PC++
Sbjct: 881 EFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNN 940
Query: 1135 GSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194
G+C+DL R+ C+C P G CE++ + C P CL CV G+ C C
Sbjct: 941 GTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISP-------CLDEENCVYRTDGYNCLCA 993
Query: 1195 PGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
PGYTG+ CE +++EC S C H C+ D + C C +GF G C+T + C S P
Sbjct: 994 PGYTGINCEINLDECLSEPC--LHDGVCI-DGINHYTCDCKSGFFGTHCETNANDCLSNP 1050
Query: 1255 CQHG--------------------------GQCRPSPGPGGGLT------FTCHCAQPFW 1282
C HG C P G FTC C + +
Sbjct: 1051 CLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYT 1110
Query: 1283 GPRCERVARSCRELQ-----CPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGSPPGASN 1336
G CE+ +C E + C G C P C C PG SG C +
Sbjct: 1111 GAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCE--------INI 1162
Query: 1337 ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
C+++PCLHG C + C C GW+G CE
Sbjct: 1163 NECSSSPCLHGADCEDHING--YVCKCQPGWSGHHCE 1197
Score = 471 bits (1211), Expect = e-132
Identities = 248/725 (34%), Positives = 361/725 (49%), Gaps = 49/725 (6%)
Query: 49 CANGGRC-TQLPSREAACLCPPGWVGERCQLEDPC--HSGPCAGRGVCQSSVVAGTARFS 105
CANG C ++ S+E LC W G LE+ C VC+ + R
Sbjct: 535 CANGCSCLSEEDSQEYRYLCFLRWAGNM-YLENTTDDQENECQHEAVCKDEI----NRPR 589
Query: 106 CRCPRGFRGPDCSLP-DPCLS--SPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDEC 162
C C + G C + D CL S HG ++ + CS Y+ C D ++C
Sbjct: 590 CSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCN--CSGLQRYERNICEIDTEDC 647
Query: 163 RVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC-RQSGDLT-- 219
+ C++G T + G F +C G+ G CE CA PC+NG TC Q G+
Sbjct: 648 KSAS-CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFCQ 706
Query: 220 ----------YDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQ 269
+ C C PG+ G CE ++DDC + C + TC D +Y C C +W G
Sbjct: 707 CVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGN 766
Query: 270 FCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATC 329
FC ++ +EC++ P C N TC + + C C +GWTG++CS+ I++C + C +G C
Sbjct: 767 FCEQESNECKMNP--CKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLC 824
Query: 330 HDRV--ASFYCACPMGKTGLLCHLD-DAC--VSNPCHEDAICDTNPVNGRAICTCPPGFT 384
H+ F C CP TG CH + C + NPC ++ C V+ C C F
Sbjct: 825 HESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTC-LALVDANQHCICREEFE 883
Query: 385 GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQA 444
G C+ DV +C + C+ G C + +F C C G++G CE ++NEC S PC+N
Sbjct: 884 GKNCEIDVKDCLFLS--CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSEPCKNNG 941
Query: 445 TCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTC 504
TC+D +F C C + G +CE+D+++C+ SPC++ C R +G++C C G++G C
Sbjct: 942 TCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINC 1001
Query: 505 QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIA 564
++++DEC S PC + C+D + Y C C GF GT C+ N +DC +PC HGRC + I
Sbjct: 1002 EINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELIN 1061
Query: 565 SFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC 624
+ C+C T T+C+ ++++C S PC + G C + C CP G TG CE +ID+C
Sbjct: 1062 EYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNC 1121
Query: 625 ASNPCTF------GVCRDGI-NRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
A G+C DG + +DC C PGF+G C + INEC+SSPC G C D N
Sbjct: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN 1181
Query: 678 GFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWS----GPRCSQSL 733
G+ C C PG C C C H +C + G C+C PG+ G C +
Sbjct: 1182 GYVCKCQPGWSGHHC-ENELECIPNSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEI 1240
Query: 734 ARDAC 738
R C
Sbjct: 1241 RRITC 1245
Score = 368 bits (945), Expect = e-101
Identities = 194/588 (32%), Positives = 280/588 (47%), Gaps = 54/588 (9%)
Query: 48 PCANGGRCTQLPSR-------------EAACLCPPGWVGERCQLE-DPCHSGPCAGRGVC 93
PC NG C P +CLC PG+VG RC+ + D C C C
Sbjct: 689 PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTC 748
Query: 94 QSSVVAGTARFSCRCPRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQG 152
+ ++ + C C + G C + C +PC + + C+ + C C G+ G
Sbjct: 749 KDLHLS----YQCVCLSDWEGNFCEQESNECKMNPCKNNSTCT-DLYKSYRCECTSGWTG 803
Query: 153 RSCRSDVDECRVGEPCRHGGTCLNT--PGSFRCQCPAGYTGPLCENPAVPC--APSPCRN 208
++C +++EC +PC +GG C + PG F C CP YTG C C +PCRN
Sbjct: 804 QNCSEEINECD-SDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRN 862
Query: 209 GGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG 268
TC D C C FEG+NCE++V DC C + G C D VN + C C P ++G
Sbjct: 863 NSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSG 922
Query: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT 328
C +++EC +P C N GTC + C C + G C +++ C + C
Sbjct: 923 SLCEIEINECSSEP--CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEEN 980
Query: 329 CHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGA 387
C R + C C G TG+ C ++ D C+S PC D +C + +N C C GF G
Sbjct: 981 CVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVC-IDGIN-HYTCDCKSGFFGTH 1038
Query: 388 CDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCL 447
C+ + ++C +NPC H GRC + C C T +C+ +N+C S PC N+ C
Sbjct: 1039 CETNANDCL--SNPCLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQ 1095
Query: 448 DRIGQFTCICMAGFTGTYCEVDIDEC-----QSSPCVNGGVCKDRV-NGFSCTCPSGFSG 501
FTCIC G+TG YCE ID C S C+NGG+C D + F C C GFSG
Sbjct: 1096 KSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSG 1155
Query: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVD 561
C+++++EC+S+PC +GA C D +GY C+C G+ G C+ + +C P+ C H C++
Sbjct: 1156 QFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHELCME 1214
Query: 562 GIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 609
+C C PG+ C G C D + + C P
Sbjct: 1215 NEPGSTCLCTPGF--------------MTCSIGLLCGDEIRRITCLTP 1248
Score = 267 bits (682), Expect = 1e-70
Identities = 233/943 (24%), Positives = 325/943 (34%), Gaps = 226/943 (23%)
Query: 702 EPCS-HGICYDAPGG--FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSS-----DG 753
E CS HG C + C C+P +SG C + DAC +PC+ G+C + D
Sbjct: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQEL---DACSFKPCKNNGSCINKRENWDE 237
Query: 754 MGFHCTCPPGVQGRQC-ELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVD 812
+ C C P G+ C E++ C P+ C HG C + +C C + + GP C+
Sbjct: 238 QAYECVCHPPFTGKNCSEIIGQCQPHVCFHGN-CSNITSNSFICECDEQFSGPFCEVSAK 296
Query: 813 ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSC-------- 864
C GIC N + +++ C G + + + D+++ PC NG C
Sbjct: 297 PCVSLL-FWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVM 355
Query: 865 ---------------QDGVGSFS---------------CSCLPGFAGPRCARDVDE---- 890
Q SF CSC+ GF C + +D
Sbjct: 356 CICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
Query: 891 ------------------------CLSNPCG-------------------PGTCTDH-VA 906
C NPC G C D A
Sbjct: 416 SINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPA 475
Query: 907 SFTCTCPPGYGGF-----------------HCEQDL-----PDCSPSSCF---------- 934
F G+ G +C +D P+ + SSC+
Sbjct: 476 QFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEIC 535
Query: 935 -NGGTCVDGVNS--FSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
NG +C+ +S + LC + G C H VC RC+C S
Sbjct: 536 ANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLS 595
Query: 992 FTGPQCQTLVDWC-SRQPCQNGGRCVQTGAYCLCP--PGWSGRLCDIRSLPCREAAAQIG 1048
+ G C VD+C G C+ C C + +C+I + C+ A+
Sbjct: 596 YIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDCKSAS---- 651
Query: 1049 VRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC 1108
C+ G + C G G+ CE ++D C + PC++G TC G Y C
Sbjct: 652 ------CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFC 705
Query: 1109 ECLP--------------GYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLG 1154
+C+P GY G CE D+D+C C+H +C DL Y C C G
Sbjct: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEG 765
Query: 1155 VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS--- 1211
CE ++C P C +N TC DL +RC C G+TG C +INEC S
Sbjct: 766 NFCEQESNECKMNP-------CKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPC 818
Query: 1212 ---GACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCE--SQPCQHGGQCRPSPG 1266
G CH + G F CLC ++G C + C+ PC++ C
Sbjct: 819 MNGGLCHESTIP-------GQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
Query: 1267 PGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR- 1325
C C + F G CE + C L C C+ RC C PG SG C
Sbjct: 872 ANQH----CICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEI 927
Query: 1326 --SFPGSPPGASNASCAAAPCLHGGSCRPAPLAPF------------------------- 1358
+ S P +N +C +C P PF
Sbjct: 928 EINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDG 987
Query: 1359 FRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCS 1418
+ C CA G+TG CE E EP C CD C S G+ G C
Sbjct: 988 YNCLCAPGYTGINCE--INLDECLSEPCLHDGVCIDGINHYTCD--CKS---GFFGTHCE 1040
Query: 1419 LSVGDPW-RQCEALQCWRLFNN--SRCDPACSSPACLYDNFDC 1458
+ D C +C L N CD +S C DC
Sbjct: 1041 TNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDC 1083
Score = 260 bits (664), Expect = 1e-68
Identities = 150/466 (32%), Positives = 209/466 (44%), Gaps = 45/466 (9%)
Query: 45 DGSPCANGGRC--TQLPSREAACLCPPGWVGERC----QLEDPCHSGPCAGRGVCQSSVV 98
D PC NGG C + +P + CLCPP + G+ C L D H+ PC C + V
Sbjct: 814 DSDPCMNGGLCHESTIPG-QFVCLCPPLYTGQFCHQRYNLCDLLHN-PCRNNSTCLALV- 870
Query: 99 AGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157
A C C F G +C + CL C C F C C PG+ G C
Sbjct: 871 --DANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE-DMVNNFRCICRPGFSGSLCEI 927
Query: 158 DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 217
+++EC EPC++ GTC++ F C C Y GP CE C SPC + C D
Sbjct: 928 EINECS-SEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD 986
Query: 218 LTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Y+C C PG+ G NCE+N+D+C CL+ G C+DG+N Y C C + G C + ++
Sbjct: 987 -GYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNAND 1045
Query: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFY 337
C P H G C + + C C T C I+DC + C + C F
Sbjct: 1046 CLSNP-CLH--GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFT 1102
Query: 338 CACPMGKTGLLCHLD-DACV-----SNPCHEDAICDTNPVNGRAI-CTCPPGFTGGACDQ 390
C CP G TG C D C S C IC P G C C PGF+G C+
Sbjct: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGP--GHTFDCRCLPGFSGQFCEI 1160
Query: 391 DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI 450
+++ECS ++PC H C + ++C+C G++G CE ++ EC+ C ++ C++
Sbjct: 1161 NINECS--SSPCLHGADCEDHINGYVCKCQPGWSGHHCENEL-ECIPNSCVHE-LCMENE 1216
Query: 451 GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCP 496
TC+C GF C G +C D + +C P
Sbjct: 1217 PGSTCLCTPGF--------------MTCSIGLLCGDEIRRITCLTP 1248
Score = 210 bits (535), Expect = 1e-53
Identities = 189/785 (24%), Positives = 269/785 (34%), Gaps = 157/785 (20%)
Query: 808 QQDVDECAGPAPCGPHGICTNLAGS--FSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 865
QQ E C HG C + A S +SC C ++G C Q+++ C PC N GSC
Sbjct: 171 QQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYC-QELDACSFKPCKNNGSCI 229
Query: 866 D-----GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVA-SFTCTCPPGYGGF 919
+ ++ C C P F G C+ + +C + C G C++ + SF C C + G
Sbjct: 230 NKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGP 289
Query: 920 HCEQDLPDC----------SPSS----------------------------CFNGGTCVD 941
CE C P+S C NG C+
Sbjct: 290 FCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIK 349
Query: 942 GVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLV 1001
N C+C P +T C+ C S P + C + C+C+ FT C+ +
Sbjct: 350 ISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAI 409
Query: 1002 DWCSRQP--CQNGGRCVQ-TGAY-CLCPPGWSGRLCDI--RSLPCREAAAQIGVRLEQLC 1055
D C C N C G + +C PG + C + GV +C
Sbjct: 410 DHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGIC 469
Query: 1056 QAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP--CLAQPC-------------------Q 1094
Q G E + + G G C+ +D LA C
Sbjct: 470 QDKGPAQFE--YVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWFP 527
Query: 1095 HGGTCRGYMGGYMC-----------ECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
H GT G C C + G+ ++ + CQH C D + R
Sbjct: 528 HEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEINR 587
Query: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCL---HNGTC------------------ 1182
CSC +G LC +N D C + CL HN C
Sbjct: 588 PRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTEDC 647
Query: 1183 -----------VDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGG--- 1228
L G F C PG+ G +CE DI+EC S C T C+ PG
Sbjct: 648 KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGAT--CIDQPGNYFC 705
Query: 1229 ----------GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCA 1278
GF CLC+ G+ G RC+ + C C+H C+ L++ C C
Sbjct: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL-----HLSYQCVCL 760
Query: 1279 QPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNAS 1338
+ G CE+ + C+ C C + RC C G +G +C
Sbjct: 761 SDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNC--------SEEINE 812
Query: 1339 CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGD 1398
C + PC++GG C + + F C C +TG C ++ P + C A
Sbjct: 813 CDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDA 872
Query: 1399 QR---CDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSR--CDPACSSPACLY 1453
+ C E C D DC + CE + NN R C P S C
Sbjct: 873 NQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE-----DMVNNFRCICRPGFSGSLCEI 927
Query: 1454 DNFDC 1458
+ +C
Sbjct: 928 EINEC 932
Score = 68.9 bits (167), Expect = 5e-11
Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQ---PNACHNGGT 290
+ + C +C NGGTC++ + C C W G FCTE V C + P+ C G T
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 291 CFNTLGGHSCVCVNGWTGESCSQ 313
C + G++C C G TG C Q
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 66.2 bits (160), Expect = 3e-10
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 198 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC-----PGHRCLNGGTCV 252
A PC+ C NGGTC +SG Y C C G++G C V C P H C G TC+
Sbjct: 2611 ASPCSLMKCGNGGTCIESGTSVY-CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCI 2669
Query: 253 DGVNTYNCQCPPEWTGQFCTE 273
+ Y C CP TG +C +
Sbjct: 2670 SLPHGYTCFCPLGTTGIYCEQ 2690
Score = 62.8 bits (151), Expect = 4e-09
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 7/89 (7%)
Query: 1075 GRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQ----- 1129
GR+ C PC C +GGTC C C G+ G C + V C +
Sbjct: 2603 GRSVGQCH--ASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
C G +CI L Y C CP GT G+ CE
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 62.4 bits (150), Expect = 5e-09
Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS 797
C CR GTC SD C CP G+ C+ S C NPC +G C G VC
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTDIVCL 2397
Query: 798 CPQGWQGPRCQQDVD 812
CP G GP C ++
Sbjct: 2398 CPYGRSGPLCTDAIN 2412
Score = 61.6 bits (148), Expect = 9e-09
Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 7/112 (6%)
Query: 40 APPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVV 98
A P L+ C NGG C P C C PG+ G+ C++ + C S PC C+ +
Sbjct: 1122 AEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHIN 1181
Query: 99 AGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY 150
+ C+C G+ G C C+ + C H C G C C PG+
Sbjct: 1182 G----YVCKCQPGWSGHHCENELECIPNSCVH-ELCMENEPGS-TCLCTPGF 1227
Score = 59.7 bits (143), Expect = 3e-08
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 371 VNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCET 430
+N + + G GG+ D D + G N C + G C +F C+C + G C
Sbjct: 2853 INNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ 2912
Query: 431 DVNECLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCE 467
V+ CL+ C +Q+ C+ D+ ++C+C G+ G YCE
Sbjct: 2913 SVS-CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 59.7 bits (143), Expect = 3e-08
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 5/79 (6%)
Query: 194 CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCV- 252
C+ A C + CRNGG C +G T+ C CLP + G C +V C + CL+ C+
Sbjct: 2874 CDGTA--CGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIP 2929
Query: 253 DGVNTYNCQCPPEWTGQFC 271
D +Y+C C W G++C
Sbjct: 2930 DQSFSYSCLCTLGWVGRYC 2948
Score = 59.3 bits (142), Expect = 4e-08
Identities = 29/86 (33%), Positives = 38/86 (44%), Gaps = 11/86 (12%)
Query: 544 RNVDDCSPDPC------HHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP-----CR 592
R+V C PC + G C++ S C C G+ G+ C V C + C
Sbjct: 2604 RSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
Query: 593 HGGKCLDLVDKYLCRCPSGTTGVNCE 618
G C+ L Y C CP GTTG+ CE
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 59.3 bits (142), Expect = 4e-08
Identities = 28/83 (33%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 275 VDECQLQPNA---CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC-----ATAVCFHG 326
V +C P + C NGGTC + C C GW G C++ + C C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 327 ATCHDRVASFYCACPMGKTGLLC 349
ATC + C CP+G TG+ C
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
Score = 58.9 bits (141), Expect = 6e-08
Identities = 30/91 (32%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
Query: 1118 NCEDDVDECASQPCQ-----HGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS 1172
N V +C + PC +GG+CI+ C+C G G C C P D
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH--DP 2658
Query: 1173 GPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
C TC+ L G+ C CP G TG+ CE
Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 58.2 bits (139), Expect = 9e-08
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 10/92 (10%)
Query: 470 IDECQSSPCV-----NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC-----ASTPCRNG 519
+ +C +SPC NGG C + C C +G+ GS C V C C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 520 AKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP 551
A C+ P GY C C G G C++ + P
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDP 2697
Score = 58.2 bits (139), Expect = 9e-08
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 1004 CSRQPCQNGGRCVQTGA--YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
CS C NGG C+++G YC C GW G C C C G C
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDP-----PHHCSRGATC 2668
Query: 1062 VDEDSSHYCVCPEGRTGSHCEQ 1083
+ + C CP G TG +CEQ
Sbjct: 2669 ISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 57.8 bits (138), Expect = 1e-07
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 236 NVDDCPG-----HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
NV DC G + C NGG C T++C+C P+W G C + V N C +
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSL 2926
Query: 291 CF-NTLGGHSCVCVNGWTGESC 311
C + +SC+C GW G C
Sbjct: 2927 CIPDQSFSYSCLCTLGWVGRYC 2948
Score = 57.4 bits (137), Expect = 2e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 768 QCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG----PAPCGPH 823
QC SPC+ C +GG C + G C+C GW+G C + V C P C
Sbjct: 2608 QCHA-SPCSLMKCGNGGTCIES-GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 824 GICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
C +L ++C C G TG C+Q ++ DP+
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 57.4 bits (137), Expect = 2e-07
Identities = 32/78 (41%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTC-TDH 904
D D C N C NGG C +FSC CLP +AG C + V CL+N C C D
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 905 VASFTCTCPPGYGGFHCE 922
S++C C G+ G +CE
Sbjct: 2932 SFSYSCLCTLGWVGRYCE 2949
Score = 57.0 bits (136), Expect = 2e-07
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 11/99 (11%)
Query: 844 PSCDQDINDCDPNPCL-----NGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-----LS 893
P+ + + C +PC NGG+C + S C+C G+ G C V C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 894 NPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS 931
+ C G TC +TC CP G G +CEQ L PS
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 53.9 bits (128), Expect = 2e-06
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATC-HDR 332
D D N C NGG C SC C+ W G +C+Q++ C +C H + C D+
Sbjct: 2873 DCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQ 2931
Query: 333 VASFYCACPMGKTGLLC 349
S+ C C +G G C
Sbjct: 2932 SFSYSCLCTLGWVGRYC 2948
Score = 53.1 bits (126), Expect = 3e-06
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 17/105 (16%)
Query: 1001 VDWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAG 1058
V WC+ C+N G C+ +C CP +SG+LC S C G
Sbjct: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCE------------NNPCGNG 2383
Query: 1059 GQCVDEDSSH-YCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY 1102
CV + + C+CP GR+G C ++ + QP G GY
Sbjct: 2384 ATCVPKSGTDIVCLCPYGRSGPLCTDAIN--ITQPRFSGTDAFGY 2426
Score = 53.1 bits (126), Expect = 3e-06
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
CR+ GTC++ + C+CP Y+G LC+ C +PC NG TC C C G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 228 FEGQNC 233
G C
Sbjct: 2402 RSGPLC 2407
Score = 53.1 bits (126), Expect = 3e-06
Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 5/87 (5%)
Query: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP----CRHGGTCLNT 177
PC C +G C + C+C G++G C V C C G TC++
Sbjct: 2613 PCSLMKCGNGGTC-IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL 2671
Query: 178 PGSFRCQCPAGYTGPLCENPAVPCAPS 204
P + C CP G TG CE PS
Sbjct: 2672 PHGYTCFCPLGTTGIYCEQALSISDPS 2698
Score = 52.8 bits (125), Expect = 4e-06
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 507 DVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCV-DGIA 564
D C CRNG +C + CRC + G C+++V C + C H C+ D
Sbjct: 2875 DGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSF 2933
Query: 565 SFSCACAPGYTGTRCESQ 582
S+SC C G+ G CE++
Sbjct: 2934 SYSCLCTLGWVGRYCENK 2951
Score = 52.4 bits (124), Expect = 5e-06
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 881 GPRCARDVDECLSNPCG------PGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
G + +V +C CG G CT + +F+C C P + G C Q + C + C
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCL 2922
Query: 935 NGGTCV-DGVNSFSCLCRPGYTGAHCQHE 962
+ C+ D S+SCLC G+ G +C+++
Sbjct: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCENK 2951
Score = 52.0 bits (123), Expect = 7e-06
Identities = 93/368 (25%), Positives = 124/368 (33%), Gaps = 78/368 (21%)
Query: 308 GESCSQ-NIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP------- 359
G S Q + C+ C +G TC + S YC C G G C + +P
Sbjct: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFC-TETVSTCDPEHDPPHH 2661
Query: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQ--DVDECSIGANPCE-------HLGRCVN 410
C A C + P C CP G TG C+Q + + S +N H+ + +
Sbjct: 2662 CSRGATCISLPHG--YTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTH 2719
Query: 411 TQGSFLCQCGRG---YTGPRCETDVNECLSGPCRNQATCL-----DRI------------ 450
Q F G Y + + L N + L DR
Sbjct: 2720 IQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKVTIN 2779
Query: 451 GQFTCICMAGFTGTYCEVDIDEC---------QSSPCVN-----GGVCK-DRVNGFSC-T 494
G I AG G +D+D SS N GGV + VN +
Sbjct: 2780 GSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIEN 2839
Query: 495 CPSGFSGSTCQLDVDECASTPCRNGAK---CVDQPDGYECRCAEGFEGTLCDRNVDDCSP 551
P GF G Q+ ++ GAK V DG C G RN +C+
Sbjct: 2840 EPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTAC-------GYNTCRNGGECT- 2891
Query: 552 DPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCL-DLVDKYLCRCPS 610
V+G +FSC C P + G C V C + C H C+ D Y C C
Sbjct: 2892 --------VNG-TTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTL 2941
Query: 611 GTTGVNCE 618
G G CE
Sbjct: 2942 GWVGRYCE 2949
Score = 52.0 bits (123), Expect = 7e-06
Identities = 26/71 (36%), Positives = 31/71 (43%), Gaps = 5/71 (7%)
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ-----PCQHGGTCRGYMGGYMCE 1109
C GG C++ +S YC C G GS C + V C + C G TC GY C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 1110 CLPGYNGDNCE 1120
C G G CE
Sbjct: 2679 CPLGTTGIYCE 2689
Score = 52.0 bits (123), Expect = 7e-06
Identities = 25/72 (34%), Positives = 28/72 (38%)
Query: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
AC CR GG C+ +G F C C P G C C N C H C C
Sbjct: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 797 SCPQGWQGPRCQ 808
C GW G C+
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 51.6 bits (122), Expect = 9e-06
Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 231 QNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
+NC +V C H C N GTC+ C+CP ++G+ C + N C NG T
Sbjct: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC----QFASCENNPCGNGAT 2385
Query: 291 CFNTLGGH-SCVCVNGWTGESCSQNID 316
C G C+C G +G C+ I+
Sbjct: 2386 CVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 51.6 bits (122), Expect = 9e-06
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 11/94 (11%)
Query: 652 PLCNVEINECASSPC-----GEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC--AHEP- 703
P + +C +SPC G GG+C++ C C G C C H+P
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 704 --CSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLA 734
CS G C P G+ C C G +G C Q+L+
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
Score = 51.6 bits (122), Expect = 9e-06
Identities = 26/77 (33%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 698 PCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP---CRAGGTCSSDG 753
PC+ C +G C ++ C C GW G C+++++ E P C G TC S
Sbjct: 2613 PCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP 2672
Query: 754 MGFHCTCPPGVQGRQCE 770
G+ C CP G G CE
Sbjct: 2673 HGYTCFCPLGTTGIYCE 2689
Score = 51.2 bits (121), Expect = 1e-05
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 2/87 (2%)
Query: 149 GYQGRSCRSDVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCR 207
G +G S D D G CR+GG C +F C+C + G C N +V C + C
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCL 2922
Query: 208 NGGTCRQSGDLTYDCACLPGFEGQNCE 234
+ C +Y C C G+ G+ CE
Sbjct: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 50.8 bits (120), Expect = 2e-05
Identities = 34/114 (29%), Positives = 42/114 (36%), Gaps = 16/114 (14%)
Query: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP-DGYEC 531
C C N G C C CP +SG CQ C + PC NGA CV + C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCENNPCGNGATCVPKSGTDIVC 2396
Query: 532 RCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDE 585
C G G LC ++ P FS A GYT S++ +
Sbjct: 2397 LCPYGRSGPLCTDAINITQP-------------RFSGTDAFGYTSFLAYSRISD 2437
Score = 50.8 bits (120), Expect = 2e-05
Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 10/90 (11%)
Query: 426 PRCETDVNECLSGPCR-----NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS---- 476
P V +C + PC N TC++ C C G+ G++C + C
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 477 -PCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
C G C +G++C CP G +G C+
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 50.8 bits (120), Expect = 2e-05
Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC-ELLSPC-----TPNPCEHGGRCESAPG 791
C C GGTC G +C C G +G C E +S C P+ C G C S P
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 792 QLPVCSCPQGWQGPRCQQ 809
C CP G G C+Q
Sbjct: 2674 GY-TCFCPLGTTGIYCEQ 2690
Score = 50.4 bits (119), Expect = 2e-05
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 5/76 (6%)
Query: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC-----LSRPCLHGGVCSAAHP 982
CS C NGGTC++ S C C G+ G+ C C C G C +
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 983 GFRCTCLESFTGPQCQ 998
G+ C C TG C+
Sbjct: 2674 GYTCFCPLGTTGIYCE 2689
Score = 50.1 bits (118), Expect = 3e-05
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Query: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIG-QFTCICMAG 460
C + G C++ + C+C R Y+G C+ C + PC N ATC+ + G C+C G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 461 FTGTYC 466
+G C
Sbjct: 2402 RSGPLC 2407
Score = 50.1 bits (118), Expect = 3e-05
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 14/84 (16%)
Query: 1004 CSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
C C+NGG C G C C P W+G C+ +S+ C L LC C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC----------LNNLCLHQSLC 2927
Query: 1062 V-DEDSSHYCVCPEGRTGSHCEQE 1084
+ D+ S+ C+C G G +CE +
Sbjct: 2928 IPDQSFSYSCLCTLGWVGRYCENK 2951
Score = 50.1 bits (118), Expect = 3e-05
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHP-GFRC 986
C ++C NGG C +FSC C P + G C +++ CL+ CLH +C + C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 987 TCLESFTGPQCQ 998
C + G C+
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 49.7 bits (117), Expect = 3e-05
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 1065 DSSHYCVCPEGRTGSHCEQ-EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
++ + + E R G + E V C C++ GTC CEC Y+G C+
Sbjct: 2315 NNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--F 2372
Query: 1124 DECASQPCQHGGSCIDLVAR-YLCSCPPGTLGVLC 1157
C + PC +G +C+ +C CP G G LC
Sbjct: 2373 ASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
Score = 48.9 bits (115), Expect = 6e-05
Identities = 32/91 (35%), Positives = 42/91 (46%), Gaps = 5/91 (5%)
Query: 191 GPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGG 249
G EN VP CA CRN GTC + + C C + G+ C+ C + C NG
Sbjct: 2328 GKNIENCHVPWCAHHLCRNNGTCISDNENLF-CECPRLYSGKLCQ--FASCENNPCGNGA 2384
Query: 250 TCVDGVNT-YNCQCPPEWTGQFCTEDVDECQ 279
TCV T C CP +G CT+ ++ Q
Sbjct: 2385 TCVPKSGTDIVCLCPYGRSGPLCTDAINITQ 2415
Score = 48.1 bits (113), Expect = 1e-04
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 2/72 (2%)
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCI-DLVARYLC 1146
C C++GG C + C CLP + G+ C V C + C H CI D Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 1147 SCPPGTLGVLCE 1158
C G +G CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 47.8 bits (112), Expect = 1e-04
Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRV-NGFSC 493
C CRN TC+ C C ++G C+ C+++PC NG C + C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
Query: 494 TCPSGFSGSTC 504
CP G SG C
Sbjct: 2397 LCPYGRSGPLC 2407
Score = 47.4 bits (111), Expect = 2e-04
Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 309 ESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDT 368
E+C ++ CA +C + TC + +C CP +G LC +C +NPC A C
Sbjct: 2332 ENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF-ASCENNPCGNGATC-- 2386
Query: 369 NPVNGR-AICTCPPGFTGGACDQDVD 393
P +G +C CP G +G C ++
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 47.0 bits (110), Expect = 2e-04
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY---C 1022
C C +GG C+ F C CL + G C V C C + C+ ++ C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSC 2937
Query: 1023 LCPPGWSGRLCD 1034
LC GW GR C+
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 46.2 bits (108), Expect = 4e-04
Identities = 35/130 (26%), Positives = 51/130 (39%), Gaps = 27/130 (20%)
Query: 536 GFEGTLCDRNVDDCS---PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCR 592
GF G + D V++ D HG+ ++ V C CR
Sbjct: 2304 GFRGCILDLQVNNKEFFIIDEARHGKNIENC------------------HVPWCAHHLCR 2345
Query: 593 HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG---VCRDGINRYDCVCQPGF 649
+ G C+ + C CP +G C+ C +NPC G V + G + C+C G
Sbjct: 2346 NNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTD-IVCLCPYGR 2402
Query: 650 TGPLCNVEIN 659
+GPLC IN
Sbjct: 2403 SGPLCTDAIN 2412
Score = 46.2 bits (108), Expect = 4e-04
Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 6/86 (6%)
Query: 804 GPRCQQDVDECAGPA----PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL 859
G + +V +C G A C G CT +FSC C + G +C+Q ++ C N CL
Sbjct: 2864 GAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCL 2922
Query: 860 NGGSC-QDGVGSFSCSCLPGFAGPRC 884
+ C D S+SC C G+ G C
Sbjct: 2923 HQSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 45.8 bits (107), Expect = 5e-04
Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 1109 ECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGP 1168
E G N +NC V CA C++ G+CI C CP G LC+ + P
Sbjct: 2324 EARHGKNIENCH--VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP-- 2379
Query: 1169 PLDSGPRCLHNGTCVDLVG-GFRCTCPPGYTGLRCEADIN 1207
C + TCV G C CP G +G C IN
Sbjct: 2380 -------CGNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 45.8 bits (107), Expect = 5e-04
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 12/95 (12%)
Query: 1235 HAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCR 1294
+AG S +C SPC C +GG C S G + C+C + G C +C
Sbjct: 2601 NAGRSVGQCHA--SPCSLMKCGNGGTCIES-----GTSVYCNCTTGWKGSFCTETVSTCD 2653
Query: 1295 ELQ-----CPVGVPCQQTPRGPRCACPPGLSGPSC 1324
C G C P G C CP G +G C
Sbjct: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYC 2688
Score = 45.4 bits (106), Expect = 6e-04
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
C +NGTC+ C CP Y+G C+ C + C T C+ G CLC
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGAT--CVPKSGTDIVCLCP 2399
Query: 1236 AGFSGPRCQTVLS 1248
G SGP C ++
Sbjct: 2400 YGRSGPLCTDAIN 2412
Score = 45.4 bits (106), Expect = 6e-04
Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 960 QHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ-----PCQNGGR 1014
Q A PC C +GG C + C C + G C V C + C G
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 1015 CVQT--GAYCLCPPGWSGRLCD 1034
C+ G C CP G +G C+
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCE 2689
Score = 45.1 bits (105), Expect = 8e-04
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 4/76 (5%)
Query: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGR 141
C C G C V GT FSCRC + G C+ CL++ C H + C
Sbjct: 2879 CGYNTCRNGGEC---TVNGTT-FSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFS 2934
Query: 142 FLCSCPPGYQGRSCRS 157
+ C C G+ GR C +
Sbjct: 2935 YSCLCTLGWVGRYCEN 2950
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGR 141
C C G C ++ C CPR + G C C ++PC +GA C
Sbjct: 2339 CAHHLCRNNGTC----ISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCVPKSGTD 2393
Query: 142 FLCSCPPGYQGRSCRSDVDECRVGEPCRHGGT 173
+C CP G G C D + +P R GT
Sbjct: 2394 IVCLCPYGRSGPLC---TDAINITQP-RFSGT 2421
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 1054 LCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMG-GYMCECLP 1112
LC+ G C+ ++ + +C CP +G C + C PC +G TC G +C C
Sbjct: 2343 LCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 1113 GYNGDNCEDDVD 1124
G +G C D ++
Sbjct: 2401 GRSGPLCTDAIN 2412
Score = 43.9 bits (102), Expect = 0.002
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVC-SAAHPG 983
+P C+ C N GTC+ + C C Y+G CQ + C + PC +G C +
Sbjct: 2336 VPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTD 2393
Query: 984 FRCTCLESFTGPQCQTLVD 1002
C C +GP C ++
Sbjct: 2394 IVCLCPYGRSGPLCTDAIN 2412
Score = 43.9 bits (102), Expect = 0.002
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 699 CAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTC-SSDGMGF 756
CAH C ++G C C C +SG C + +CE+ PC G TC G
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFA----SCENNPCGNGATCVPKSGTDI 2394
Query: 757 HCTCPPGVQGRQC 769
C CP G G C
Sbjct: 2395 VCLCPYGRSGPLC 2407
Score = 43.9 bits (102), Expect = 0.002
Identities = 21/88 (23%), Positives = 35/88 (39%), Gaps = 11/88 (12%)
Query: 616 NCEVNIDDCASNPCTF------GVCRDGINRYDCVCQPGFTGPLCNVEINEC-----ASS 664
N ++ C ++PC+ G C + C C G+ G C ++ C
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 665 PCGEGGSCVDGENGFRCLCPPGSLPPLC 692
C G +C+ +G+ C CP G+ C
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYC 2688
Score = 43.9 bits (102), Expect = 0.002
Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 4/75 (5%)
Query: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPG-SF 181
C + C +G C+V F C C P + G +C V C + C H C+ S+
Sbjct: 2879 CGYNTCRNGGECTVNGT-TFSCRCLPDWAGNTCNQSVS-C-LNNLCLHQSLCIPDQSFSY 2935
Query: 182 RCQCPAGYTGPLCEN 196
C C G+ G CEN
Sbjct: 2936 SCLCTLGWVGRYCEN 2950
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAP 713
N + CA C G+C+ C CP LC S C + PC +G C
Sbjct: 2333 NCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKS 2390
Query: 714 G-GFRCVCEPGWSGPRCSQSL 733
G C+C G SGP C+ ++
Sbjct: 2391 GTDIVCLCPYGRSGPLCTDAI 2411
Score = 42.7 bits (99), Expect = 0.004
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 8/80 (10%)
Query: 620 NIDDCASNPCTFGVCRDG----IN--RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCV 673
N+ DC C + CR+G +N + C C P + G CN ++ C ++ C C+
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
Query: 674 -DGENGFRCLCPPGSLPPLC 692
D + CLC G + C
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYC 2948
Score = 42.4 bits (98), Expect = 0.005
Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 4/69 (5%)
Query: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
C NGG CT + +C C P W G C C + C + +C + + +SC C
Sbjct: 2884 CRNGGECT-VNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLC---IPDQSFSYSCLC 2939
Query: 109 PRGFRGPDC 117
G+ G C
Sbjct: 2940 TLGWVGRYC 2948
Score = 42.0 bits (97), Expect = 0.007
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 5/104 (4%)
Query: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS-FSCSCLPG 878
C +G C + + C C Y+G C C+ NPC NG +C G+ C C G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPYG 2401
Query: 879 FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCE 922
+GP C ++ ++ P GT SF FH E
Sbjct: 2402 RSGPLCTDAIN--ITQPRFSGTDAFGYTSFLAYSRISDISFHYE 2443
Score = 42.0 bits (97), Expect = 0.007
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%)
Query: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC---RSGACHAAHTRDCLQDPGGGFR 1231
+C + GTC++ C C G+ G C ++ C H + C+ P G+
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLP-HGYT 2676
Query: 1232 CLCHAGFSGPRCQTVLS 1248
C C G +G C+ LS
Sbjct: 2677 CFCPLGTTGIYCEQALS 2693
Score = 42.0 bits (97), Expect = 0.007
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD-GMGF 756
C + C +G C F C C P W+G C+QS+ +C + C C D +
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV---SCLNNLCLHQSLCIPDQSFSY 2935
Query: 757 HCTCPPGVQGRQCE 770
C C G GR CE
Sbjct: 2936 SCLCTLGWVGRYCE 2949
Score = 41.6 bits (96), Expect = 0.009
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 882 PRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCV- 940
P CA + C +N GTC + C CP Y G C+ C + C NG TCV
Sbjct: 2337 PWCAHHL--CRNN----GTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVP 2388
Query: 941 DGVNSFSCLCRPGYTGAHC 959
CLC G +G C
Sbjct: 2389 KSGTDIVCLCPYGRSGPLC 2407
Score = 41.2 bits (95), Expect = 0.012
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 8/92 (8%)
Query: 343 GKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPC 402
GK CH+ C + C + C ++ N C CP ++G C S NPC
Sbjct: 2328 GKNIENCHVP-WCAHHLCRNNGTCISD--NENLFCECPRLYSGKLCQF----ASCENNPC 2380
Query: 403 EHLGRCVNTQGS-FLCQCGRGYTGPRCETDVN 433
+ CV G+ +C C G +GP C +N
Sbjct: 2381 GNGATCVPKSGTDIVCLCPYGRSGPLCTDAIN 2412
Score = 40.8 bits (94), Expect = 0.016
Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 7/101 (6%)
Query: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVAS-FTC 910
C + C N G+C + C C ++G C C +NPCG G TC + C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
Query: 911 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCR 951
CP G G C + P GT G SF R
Sbjct: 2397 LCPYGRSGPLCTDAINITQPRF---SGTDAFGYTSFLAYSR 2434
Score = 40.8 bits (94), Expect = 0.016
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
C + G C F C C P + G C ++ C + C H C+ D + CLC
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLC--LHQSLCIPDQSFSYSCLCT 2940
Query: 1236 AGFSGPRCQTVLS 1248
G+ G C+ S
Sbjct: 2941 LGWVGRYCENKTS 2953
Score = 40.0 bits (92), Expect = 0.027
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC-RGYMGGYMCECLPG 1113
C+ GG+C ++ C C G+ C Q V CL C H C Y C C G
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 1114 YNGDNCED 1121
+ G CE+
Sbjct: 2943 WVGRYCEN 2950
Score = 39.3 bits (90), Expect = 0.045
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC-TNLAGSF 833
C N C +GG C + G C C W G C Q V C C +C + + S+
Sbjct: 2879 CGYNTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSV-SCLNNL-CLHQSLCIPDQSFSY 2935
Query: 834 SCTCHGGYTGPSCD 847
SC C G+ G C+
Sbjct: 2936 SCLCTLGWVGRYCE 2949
Score = 39.3 bits (90), Expect = 0.045
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 3/71 (4%)
Query: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF-GVC-RDGINRYDC 643
C CR+GG+C + CRC G C ++ C +N C +C D Y C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 644 VCQPGFTGPLC 654
+C G+ G C
Sbjct: 2938 LCTLGWVGRYC 2948
Score = 38.9 bits (89), Expect = 0.059
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 11/83 (13%)
Query: 583 VDECRSQPCR-----HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDC-----ASNPCTFG 632
V +C + PC +GG C++ C C +G G C + C + C+ G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 633 -VCRDGINRYDCVCQPGFTGPLC 654
C + Y C C G TG C
Sbjct: 2666 ATCISLPHGYTCFCPLGTTGIYC 2688
Score = 38.5 bits (88), Expect = 0.078
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 240 CPGHRCLNGGTC-----VDGVNTYNCQCPPEWTGQFCTED 274
C C NGGTC G+ ++ C CP +TG+FC +D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 38.5 bits (88), Expect = 0.078
Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 10/90 (11%)
Query: 1116 GDNCED-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
G N D D C C++GG C + C C P G C C
Sbjct: 2868 GSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCN-QSVSC-------LNN 2919
Query: 1175 RCLHNGTCV-DLVGGFRCTCPPGYTGLRCE 1203
CLH C+ D + C C G+ G CE
Sbjct: 2920 LCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 38.5 bits (88), Expect = 0.078
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 3/71 (4%)
Query: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSH-GICY-DAPGGFRC 718
C + C GG C F C C P C S C + C H +C D + C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTC-NQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 719 VCEPGWSGPRC 729
+C GW G C
Sbjct: 2938 LCTLGWVGRYC 2948
Score = 37.0 bits (84), Expect = 0.23
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 1222 CLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF 1281
C+ D F C C +SG CQ + CE+ PC +G C P G C C
Sbjct: 2350 CISDNENLF-CECPRLYSGKLCQ--FASCENNPCGNGATCVPK----SGTDIVCLCPYGR 2402
Query: 1282 WGPRC 1286
GP C
Sbjct: 2403 SGPLC 2407
Score = 36.6 bits (83), Expect = 0.29
Identities = 20/53 (37%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query: 306 WTGESCSQNIDD-CATAVCFHGATCH-----DRVASFYCACPMGKTGLLCHLD 352
WT S S C VC +G TCH + SF C CP+ TG C D
Sbjct: 2090 WTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 36.6 bits (83), Expect = 0.29
Identities = 23/82 (28%), Positives = 28/82 (34%), Gaps = 10/82 (12%)
Query: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351
+C C G C C C P +G +C + SC CLH C
Sbjct: 2878 ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ---------SVSCLNNLCLHQSLCI 2928
Query: 1352 PAPLAPFFRCACAQGWTGPRCE 1373
P + C C GW G CE
Sbjct: 2929 PDQSFSY-SCLCTLGWVGRYCE 2949
Score = 35.4 bits (80), Expect = 0.66
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 1318 GLSGPSCRSFPGSPPGASNAS-CAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPA 1376
GL P G G +AS C+ C +GG+C + + + C C GW G C
Sbjct: 2592 GLGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVY--CNCTTGWKGSFCTETV 2649
Query: 1377 AAPEVSEEP--RCPRAA 1391
+ + +P C R A
Sbjct: 2650 STCDPEHDPPHHCSRGA 2666
Score = 35.0 bits (79), Expect = 0.86
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 5/41 (12%)
Query: 928 CSPSSCFNGGTC-----VDGVNSFSCLCRPGYTGAHCQHEA 963
C C NGGTC G+ SF C C +TG C+ +A
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
Score = 34.7 bits (78), Expect = 1.1
Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 5/40 (12%)
Query: 473 CQSSPCVNGGVC-----KDRVNGFSCTCPSGFSGSTCQLD 507
CQ C NGG C + F C CP F+G C+ D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 34.3 bits (77), Expect = 1.5
Identities = 17/42 (40%), Positives = 19/42 (45%), Gaps = 5/42 (11%)
Query: 734 ARDACESQPCRAGGTC-----SSDGMGFHCTCPPGVQGRQCE 770
A C+ C GGTC SS + F C CP GR CE
Sbjct: 2099 APSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 33.9 bits (76), Expect = 1.9
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 13/55 (23%)
Query: 155 CRSDVDECRVGEPCRHGGTC---LNTPG--SFRCQCPAGYTGPLCENPAVPCAPS 204
C+ DV C +GGTC + G SF+C CP +TG CE A PS
Sbjct: 2103 CQQDV--------CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFFPS 2149
Score = 33.5 bits (75), Expect = 2.5
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 5/47 (10%)
Query: 192 PLCENPAVPCAPSPCRNGGTCR----QSGDLTYDCACLPGFEGQNCE 234
P P+V C C NGGTC SG +++ C C F G+ CE
Sbjct: 2095 PSVAAPSV-CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 33.5 bits (75), Expect = 2.5
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 11/60 (18%)
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRC 1372
C CP SG C+ ASC PC +G +C P C C G +GP C
Sbjct: 2359 CECPRLYSGKLCQF----------ASCENNPCGNGATCVPKSGTDIV-CLCPYGRSGPLC 2407
Score = 33.1 bits (74), Expect = 3.3
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 14/81 (17%)
Query: 867 GVGSFSCSCLPGFAGPR-CARDVDECLSNPCGPGTC-----TDHVASFTCTCPPGYGGFH 920
GV + S P A P C +DV C + GTC + + SF C CP + G
Sbjct: 2085 GVDTMWTSVSPSVAAPSVCQQDV--CHNG----GTCHAIFLSSGIVSFQCDCPLHFTGRF 2138
Query: 921 CEQDLPDCSPSSCFNGGTCVD 941
CE+D PS FNG + ++
Sbjct: 2139 CEKDAGLFFPS--FNGNSYLE 2157
Score = 33.1 bits (74), Expect = 3.3
Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 5/40 (12%)
Query: 853 CDPNPCLNGGSC-----QDGVGSFSCSCLPGFAGPRCARD 887
C + C NGG+C G+ SF C C F G C +D
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.1 bits (74), Expect = 3.3
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 45 DGSPCANGGRCTQLPSREAACLCPPGWVGERC 76
+ +PC NG C + CLCP G G C
Sbjct: 2376 ENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
Score = 32.3 bits (72), Expect = 5.6
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVA 1290
S C+ C +GG C G ++F C C F G CE+ A
Sbjct: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDA 2143
Score = 32.3 bits (72), Expect = 5.6
Identities = 22/78 (28%), Positives = 28/78 (35%), Gaps = 12/78 (15%)
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
C C++ G C C C + + G C+ SC C G C P+
Sbjct: 2339 CAHHLCRNNGTCISD-----NENLFCECPRLYSGKLCQFA--SCENNPCGNGATC--VPK 2389
Query: 1310 GPR---CACPPGLSGPSC 1324
C CP G SGP C
Sbjct: 2390 SGTDIVCLCPYGRSGPLC 2407
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 517 bits (1332), Expect = e-146
Identities = 267/750 (35%), Positives = 363/750 (48%), Gaps = 90/750 (12%)
Query: 67 CPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSS 126
C GW+G C C G G C+ + G CRC G++G C D C+
Sbjct: 220 CMEGWMGPECN-RAICRQGCSPKHGSCK---LPG----DCRCQYGWQGLYC---DKCIPH 268
Query: 127 P-CAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-PGSFRCQ 184
P C HG C+ + C C + G+ C D++ C +PC +GGTC NT P ++C
Sbjct: 269 PGCVHGI-CNEP----WQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCS 323
Query: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR 244
CP GY+GP CE C PC N G+C+++ L ++C C PG+ G C N+DDC +
Sbjct: 324 CPEGYSGPNCEIAEHACLSDPCHNRGSCKETS-LGFECECSPGWTGPTCSTNIDDCSPNN 382
Query: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVN 304
C +GGTC D VN + C CPP+WTG+ C D +EC+ +P C N +C N + + C C+
Sbjct: 383 CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKP--CVNAKSCKNLIASYYCDCLP 440
Query: 305 GWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHED 363
GW G++C NI+DC C + A+C D V + C CP G G C D D C SNPC
Sbjct: 441 GWMGQNCDININDC-LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNG 499
Query: 364 AICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 423
C N +N R C CP GF+G C D+D C NPC++ +C N + C+C Y
Sbjct: 500 GHCQ-NEIN-RFQCLCPTGFSGNLCQLDIDYCE--PNPCQNGAQCYNRASDYFCKCPEDY 555
Query: 424 TGPRCETDVNECLSGPCRNQATCLDRI----------------------------GQFTC 455
G C + C + PC +C + G+FTC
Sbjct: 556 EGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTC 615
Query: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTP 515
C GFTGTYC +I++C+S+PC NGG C D VN + C C G+ G+ C+ ++++C+ P
Sbjct: 616 DCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNP 675
Query: 516 CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH-GRCVDGIASFSCACAPGY 574
C NG C D + + C C G++G C C C++ G C D +F C C G+
Sbjct: 676 CHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGW 735
Query: 575 TGTRCE-SQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFG 632
GT C ++ C PC +GG C+ + + C C G G C N +DC+ +PC G
Sbjct: 736 EGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSG 795
Query: 633 VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
C DG N Y C C PGF GP C + INEC SSPC G +CVD NG+RC+CPPG C
Sbjct: 796 TCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKC 855
Query: 693 LPPS-HPCA------------HEPCSHGICYDAPGGFRCVCEPGWSGPR----------C 729
S PC + C+ C + R C W GPR C
Sbjct: 856 QEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNG----RIACSKVWCGPRPCLLHKGHSEC 911
Query: 730 SQS-----LARDACESQPCRAGGTCSSDGM 754
+ D C PC G C S +
Sbjct: 912 PSGQSCIPILDDQCFVHPCTGVGECRSSSL 941
Score = 474 bits (1220), Expect = e-133
Identities = 258/759 (33%), Positives = 348/759 (45%), Gaps = 87/759 (11%)
Query: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFY----CACPMGKTGLLCHLDDACVS 357
C+ GW G C++ A+C G C + S C C G GL C D C+
Sbjct: 220 CMEGWMGPECNR-------AICRQG--CSPKHGSCKLPGDCRCQYGWQGLYC---DKCIP 267
Query: 358 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNT-QGSFL 416
+P IC N C C + G CD+D++ C PC + G C NT +
Sbjct: 268 HPGCVHGIC-----NEPWQCLCETNWGGQLCDKDLNYCGTH-QPCLNGGTCSNTGPDKYQ 321
Query: 417 CQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS 476
C C GY+GP CE + CLS PC N+ +C + F C C G+TG C +ID+C +
Sbjct: 322 CSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN 381
Query: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEG 536
C +GG C+D VNGF C CP ++G TCQLD +EC + PC N C + Y C C G
Sbjct: 382 NCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPG 441
Query: 537 FEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGK 596
+ G CD N++DC + C D + + C C PGY G CE +DEC S PC +GG
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGH 501
Query: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGFTGPLCN 655
C + ++++ C CP+G +G C+++ID C NPC G C + + Y C C + G C+
Sbjct: 502 CQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS 561
Query: 656 VEINECASSP---------------------------CGEGGSCVDGENG-FRCLCPPGS 687
+ C ++P CG G C G F C C G
Sbjct: 562 HLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGF 621
Query: 688 LPPLCLPPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAG 746
C + C PC + G C D ++C+C GW G C ++ + C PC G
Sbjct: 622 TGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI--NDCSQNPCHNG 679
Query: 747 GTCSSDGMGFHCTCPPGVQGRQCELL-SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGP 805
GTC F+C C G +G+ C S C C +GG C G C CP GW+G
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYD-EGDAFKCMCPGGWEGT 738
Query: 806 RCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ 865
C + P PC G C SF+C C G+ GP C Q+ NDC P+PC N G+C
Sbjct: 739 TCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCV 798
Query: 866 DGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQD 924
DG + C C PGFAGP C +++EC S+PC G TC D + + C CPPG+ G C+
Sbjct: 799 DGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ-- 856
Query: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV-CSAAHPG 983
+ S C G+ + GA + + C CL+G + CS G
Sbjct: 857 --EVSGRPCITMGSVIP-------------DGAKWDDDCNTC---QCLNGRIACSKVWCG 898
Query: 984 FRCTCL------ESFTGPQC-QTLVDWCSRQPCQNGGRC 1015
R CL E +G C L D C PC G C
Sbjct: 899 PR-PCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGEC 936
Score = 462 bits (1188), Expect = e-129
Identities = 247/746 (33%), Positives = 344/746 (46%), Gaps = 84/746 (11%)
Query: 645 CQPGFTGPLCNVEINECASSPCGEGGSC-VDGENGFRCLCP---PGSLPPLCLPPSHPCA 700
C G+ GP CN I SP + GSC + G+ C C G C+P
Sbjct: 220 CMEGWMGPECNRAICRQGCSP--KHGSCKLPGD----CRCQYGWQGLYCDKCIP------ 267
Query: 701 HEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACES-QPCRAGGTCSSDGMG-FHC 758
H C HGIC + ++C+CE W G C + L + C + QPC GGTCS+ G + C
Sbjct: 268 HPGCVHGICNEP---WQCLCETNWGGQLCDKDL--NYCGTHQPCLNGGTCSNTGPDKYQC 322
Query: 759 TCPPGVQGRQCELLS-PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGP 817
+CP G G CE+ C +PC + G C+ C C GW GP C ++D+C+ P
Sbjct: 323 SCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFE-CECSPGWTGPTCSTNIDDCS-P 380
Query: 818 APCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLP 877
C G C +L F C C +TG +C D N+C+ PC+N SC++ + S+ C CLP
Sbjct: 381 NNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLP 440
Query: 878 GFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGG 937
G+ G C ++++CL +C D V + C CPPGY G HCE+D+ +C+ + C NGG
Sbjct: 441 GWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG 500
Query: 938 TCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 997
C + +N F CLC G++G CQ + D C PC +G C + C C E + G C
Sbjct: 501 HCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNC 560
Query: 998 QTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA 1057
L D C PC+ C A P G +R + +C
Sbjct: 561 SHLKDHCRTTPCEVIDSCTVAMASNDTPEG-------VRYIS------------SNVCGP 601
Query: 1058 GGQCVDEDSSHY-CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNG 1116
G+C + + C C +G TG++C + ++ C + PC++GGTC + Y C C G+ G
Sbjct: 602 HGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEG 661
Query: 1117 DNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC 1176
CE ++++C+ PC +GG+C DLV + C C G G C + C C
Sbjct: 662 AYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEA-------TC 714
Query: 1177 LHNGTCVDLVGGFRCTCPPGYTGLRCE-ADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
+ GTC D F+C CP G+ G C A + C CH T C+ + G F C+C
Sbjct: 715 NNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGT--CVVN-GESFTCVCK 771
Query: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRE 1295
G+ GP C + C PC + G C G + C CA F GP C C+
Sbjct: 772 EGWEGPICAQNTNDCSPHPCYNSGTC-----VDGDNWYRCECAPGFAGPDCRININECQS 826
Query: 1296 LQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGS---------PPGAS-NASCAAAPCL 1345
C G C G RC CPPG SG C+ G P GA + C CL
Sbjct: 827 SPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCL 886
Query: 1346 HGGSCRPAPLAPFFRCACAQGWTGPR 1371
+G R AC++ W GPR
Sbjct: 887 NG------------RIACSKVWCGPR 900
Score = 362 bits (930), Expect = 2e-99
Identities = 235/751 (31%), Positives = 321/751 (42%), Gaps = 98/751 (13%)
Query: 797 SCPQGWQGPRCQQDVDECAGPAPCGP-HGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
+C +GW GP C + + C P HG C L G C C G+ G CD+ C P
Sbjct: 219 TCMEGWMGPECNRAICRQG----CSPKHGSC-KLPGD--CRCQYGWQGLYCDK----CIP 267
Query: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSN-PC-GPGTCTDHVAS-FTCTC 912
+P G C + + C C + G C +D++ C ++ PC GTC++ + C+C
Sbjct: 268 HPGCVHGICNE---PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 913 PPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCL 972
P GY G +CE C C N G+C + F C C PG+TG C D C C
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCS 384
Query: 973 HGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA--YCLCPPGWSG 1030
HGG C GF+C C +TG CQ + C +PC N C A YC C PGW G
Sbjct: 385 HGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMG 444
Query: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA 1090
+ CDI C L Q CQ C D + + C+CP G G HCE+++D C +
Sbjct: 445 QNCDININDC----------LGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECAS 493
Query: 1091 QPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPP 1150
PC +GG C+ + + C C G++G+ C+ D+D C PCQ+G C + + Y C CP
Sbjct: 494 NPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPE 553
Query: 1151 GTLGVLCEINEDDCGPGP--PLDS------------GPR------CLHNGTCVDLVGG-F 1189
G C +D C P +DS G R C +G C GG F
Sbjct: 554 DYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKF 613
Query: 1190 RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP 1249
C C G+TG C +IN+C S C T C+ D ++C+C G+ G C+T ++
Sbjct: 614 TCDCNKGFTGTYCHENINDCESNPCRNGGT--CI-DGVNSYKCICSDGWEGAYCETNIND 670
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
C PC +GG CR F C C + G C C E C G C
Sbjct: 671 CSQNPCHNGGTCRDLVND-----FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGD 725
Query: 1310 GPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTG 1369
+C CP G G +C A N+SC PC +GG+C F C C +GW G
Sbjct: 726 AFKCMCPGGWEGTTCNI-------ARNSSCLPNPCHNGGTC--VVNGESFTCVCKEGWEG 776
Query: 1370 PRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCE 1429
P C + S P C RC EC G+ G DC +++ +C+
Sbjct: 777 PIC--AQNTNDCSPHPCYNSGTCVDGDNWYRC--EC---APGFAGPDCRINI----NECQ 825
Query: 1430 ALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYC---ADHFADG-RCD 1485
+ C + C + C+ C G C V + C DG + D
Sbjct: 826 SSPC---AFGATCVDEINGYRCV-----CPPGHSGAKCQEVSGRPCITMGSVIPDGAKWD 877
Query: 1486 QGCNTEECGWDGLDCASEV-----PALLARG 1511
CNT +C +G S+V P LL +G
Sbjct: 878 DDCNTCQC-LNGRIACSKVWCGPRPCLLHKG 907
Score = 89.4 bits (220), Expect = 4e-17
Identities = 85/320 (26%), Positives = 115/320 (35%), Gaps = 78/320 (24%)
Query: 1184 DLVGGFRC------TCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
D G + C TC G+ G C I CR G C H L PG C C G
Sbjct: 205 DFFGHYACDQNGNKTCMEGWMGPECNRAI--CRQG-CSPKHGSCKL--PGD---CRCQYG 256
Query: 1238 FSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLT---FTCHCAQPFWGPRCERVARSCR 1294
+ G C +C P PG G+ + C C + G C++ C
Sbjct: 257 WQGLYCD---------------KCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCG 301
Query: 1295 ELQ-CPVGVPCQQT-PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP 1352
Q C G C T P +C+CP G SGP+C + +C + PC + GSC+
Sbjct: 302 THQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE--------IAEHACLSDPCHNRGSCKE 353
Query: 1353 APLAPFFRCACAQGWTGPRCEA---PAAAPEVSEEPRCP------RAACQAKRGDQRCD- 1402
L F C C+ GWTGP C + S C + C + + C
Sbjct: 354 TSLG--FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQL 411
Query: 1403 --RECNSPGC-------------------GWDGGDCSLSVGDPWRQCE-ALQCWRLFNNS 1440
EC + C GW G +C +++ D QC+ C L N
Sbjct: 412 DANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGY 471
Query: 1441 R--CDPACSSPACLYDNFDC 1458
R C P + C D +C
Sbjct: 472 RCICPPGYAGDHCERDIDEC 491
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 477 bits (1228), Expect = e-134
Identities = 264/750 (35%), Positives = 341/750 (45%), Gaps = 67/750 (8%)
Query: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCH 361
C++GW G+ C + + + G T C C G G C D CV P
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFC---DECVPYPGC 282
Query: 362 EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ-GSFLCQCG 420
C P C C + G CD+D++ C +PC + G C+N + + C C
Sbjct: 283 VHGSC-VEPWQ----CNCETNWGGLLCDKDLNYCG-SHHPCTNGGTCINAEPDQYRCTCP 336
Query: 421 RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVN 480
GY+G CE + C S PC N +C + F C C +G++G C +DIDEC S+PC
Sbjct: 337 DGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAA 396
Query: 481 GGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGT 540
GG C D+V+GF C CP + G+TCQLD +EC PC N C + GY C C G++G
Sbjct: 397 GGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGI 456
Query: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
C NV+DC H G C D + + C C G+ G CE + DEC S PC GG C DL
Sbjct: 457 NCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDL 516
Query: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGFTGPLCNVEIN 659
D + C CP G +G CEV++D C +PC G C + Y C C F G C+V
Sbjct: 517 ADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPRE 576
Query: 660 EC-----------------------ASSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPP 695
C AS CG G CV G F C+C G C
Sbjct: 577 PCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 636
Query: 696 SHPCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
C +PC + G C D FRC C GW G C + + C PC + G C
Sbjct: 637 IDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN--PNDCLPDPCHSRGRCYDLVN 694
Query: 755 GFHCTCPPGVQGRQCELLS-PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE 813
F+C C G +G+ C C C +GG C + G C+CP GW+G C +
Sbjct: 695 DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS-GDTFRCACPPGWKGSTCAVAKNS 753
Query: 814 CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC 873
P PC G C SFSC C G+ G +C + NDC+P PC NGG C DGV F C
Sbjct: 754 SCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRC 813
Query: 874 SCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 932
C PGFAGP C ++DEC S+PC G TC D + + C+CPPG G C++ + S
Sbjct: 814 ECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIG--FGRS 871
Query: 933 CFNGGTCVDGVNSF-----SCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSA--AHPGFR 985
C++ GT +S+ SC C G C +PCL G A A
Sbjct: 872 CWSRGTPFPHGSSWVEDCNSCRCLDGRRDC----SKVWCGWKPCLLAGQPEALSAQCPLG 927
Query: 986 CTCLESFTGPQCQTLVDWCSRQPCQNGGRC 1015
CLE G C R PC+ G C
Sbjct: 928 QRCLEKAPGQ--------CLRPPCEAWGEC 949
Score = 447 bits (1150), Expect = e-125
Identities = 253/765 (33%), Positives = 338/765 (44%), Gaps = 111/765 (14%)
Query: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
C G+ G +C HG C+V + C C G+QGR C DEC
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGG-CTVPGE----CRCSYGWQGRFC----DECVPYPG 281
Query: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPS-PCRNGGTCRQSGDLTYDCACLP 226
C HG +C+ ++C C + G LC+ C PC NGGTC + Y C C
Sbjct: 282 CVHG-SCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPD 337
Query: 227 GFEGQNCE--------------------------------------VNVDDCPGHRCLNG 248
G+ G+NCE +++D+C + C G
Sbjct: 338 GYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAG 397
Query: 249 GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG 308
GTCVD V+ + C CP +W G C D +EC+ +P C N +C N +GG+ C C+ GW G
Sbjct: 398 GTCVDQVDGFECICPEQWVGATCQLDANECEGKP--CLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 309 ESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICD 367
+C N++DC C HG TC D V + C CP G G C L+ D C S+PCH +C+
Sbjct: 456 INCHINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCE 514
Query: 368 TNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR 427
+ C CP GF+G C+ DVD C +PC + RC N +G + C C + G
Sbjct: 515 --DLADGFHCHCPQGFSGPLCEVDVDLCE--PSPCRNGARCYNLEGDYYCACPDDFGGKN 570
Query: 428 CETDVNECLSGPCR-----------------------NQATCLDRI-GQFTCICMAGFTG 463
C C G CR C+ + G F+CIC +GFTG
Sbjct: 571 CSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTG 630
Query: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCV 523
TYC +ID+C PC NGG C D V+ F C CPSG+ G C + ++C PC + +C
Sbjct: 631 TYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCY 690
Query: 524 DQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH-GRCVDGIASFSCACAPGYTGTRCE-S 581
D + + C C +G++G C C C + G C D +F CAC PG+ G+ C +
Sbjct: 691 DLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVA 750
Query: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINR 640
+ C PC +GG C+ + C C G G C N +DC PC G+C DG+N
Sbjct: 751 KNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNW 810
Query: 641 YDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPP---------- 690
+ C C PGF GP C + I+EC SSPC G +CVD NG+RC CPPG P
Sbjct: 811 FRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 870
Query: 691 LCLPPSHPCAH-----EPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRA 745
C P H E C+ C D R C W G + + S C
Sbjct: 871 SCWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSKVWCGWKPCLLAGQPEALSAQCPL 926
Query: 746 GGTCSSDGMGFHCTCPP----GVQGRQCELLSPCTPNPCEHGGRC 786
G C G C PP G G + +PC P C
Sbjct: 927 GQRCLEKAPG-QCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNC 970
Score = 402 bits (1032), Expect = e-111
Identities = 240/696 (34%), Positives = 316/696 (45%), Gaps = 86/696 (12%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 101
C PC NGG C + C CP G+ G C+ E C S PCA G C V +G
Sbjct: 311 CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCH-EVPSG- 368
Query: 102 ARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
F C CP G+ GP C+L D C S+PCA G C DG F C CP + G +C+ D +
Sbjct: 369 --FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDAN 425
Query: 161 ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT- 219
EC G+PC + +C N G + C C G+ G C C C++GGTC+ DL
Sbjct: 426 ECE-GKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCR-GQCQHGGTCK---DLVN 480
Query: 220 -YDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDEC 278
Y C C GF G++CE+ D+C C +GG C D + ++C CP ++G C DVD C
Sbjct: 481 GYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLC 540
Query: 279 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS-----------QNIDDC--------- 318
+P+ C NG C+N G + C C + + G++CS + ID C
Sbjct: 541 --EPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMP 598
Query: 319 ---ATAVCF-HGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNG 373
A+ VC HG +F C C G TG CH + D C+ PC C
Sbjct: 599 GTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAF 658
Query: 374 RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 433
R C CP G+ G CD + ++C +PC GRC + F C C G+ G C +
Sbjct: 659 R--CFCPSGWEGELCDTNPNDCL--PDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 714
Query: 434 ECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV-DIDECQSSPCVNGGVCKDRVNGFS 492
+C + C N TC D F C C G+ G+ C V C +PCVNGG C FS
Sbjct: 715 QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS 774
Query: 493 CTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPD 552
C C G+ G TC + ++C PC NG CVD + + C CA GF G C N+D+C
Sbjct: 775 CICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSS 834
Query: 553 PCHHG-RCVDGIASFSCACAPGYTGTRCESQVD---EC--RSQPCRHGGKCLDLVDKYLC 606
PC +G CVD I + C+C PG G RC+ + C R P HG ++ D C
Sbjct: 835 PCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVE--DCNSC 892
Query: 607 RCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
RC G DC+ C + C QP E S+ C
Sbjct: 893 RCLDGRR---------DCSKVWCGWKPCL-------LAGQP------------EALSAQC 924
Query: 667 GEGGSCVDGENGFRCLCPPGSLPPLC---LPPSHPC 699
G C++ G +CL PP C PPS PC
Sbjct: 925 PLGQRCLEKAPG-QCLRPPCEAWGECGAEEPPSTPC 959
Score = 359 bits (922), Expect = 2e-98
Identities = 240/749 (32%), Positives = 319/749 (42%), Gaps = 90/749 (12%)
Query: 797 SCPQGWQGPRCQQDVDECAGPAPCGP-HGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
+C GW G C++ V + C HG CT + G C C G+ G CD+ C P
Sbjct: 230 ACMDGWMGKECKEAVCKQG----CNLLHGGCT-VPGE--CRCSYGWQGRFCDE----CVP 278
Query: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSN-PC-GPGTCTD-HVASFTCTC 912
P GSC V + C+C + G C +D++ C S+ PC GTC + + CTC
Sbjct: 279 YPGCVHGSC---VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTC 335
Query: 913 PPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCL 972
P GY G +CE+ C+ + C NGG+C + + F C C G++G C + D C S PC
Sbjct: 336 PDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCA 395
Query: 973 HGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPGWSG 1030
GG C GF C C E + G CQ + C +PC N C G YC C PGW G
Sbjct: 396 AGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA 1090
C I CR CQ GG C D + + CVCP G G HCE E D C +
Sbjct: 456 INCHINVNDCRGQ-----------CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECAS 504
Query: 1091 QPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPP 1150
PC GG C G+ C C G++G CE DVD C PC++G C +L Y C+CP
Sbjct: 505 SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPD 564
Query: 1151 GTLGVLCEINEDDC---------------GPG-PPLDSGPRCLHNGTCVDLVGG-FRCTC 1193
G C + + C GPG P + C +G CV GG F C C
Sbjct: 565 DFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC 624
Query: 1194 PPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQ 1253
G+TG C +I++C C T C+ D FRC C +G+ G C T + C
Sbjct: 625 DSGFTGTYCHENIDDCLGQPCRNGGT--CI-DEVDAFRCFCPSGWEGELCDTNPNDCLPD 681
Query: 1254 PCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRC 1313
PC G+C F C C + G C C C G C + RC
Sbjct: 682 PCHSRGRCYDLVN-----DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRC 736
Query: 1314 ACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
ACPPG G +C A N+SC PC++GG+C + + F C C GW G C
Sbjct: 737 ACPPGWKGSTCAV-------AKNSSCLPNPCVNGGTCVGSGAS--FSCICRDGWEGRTC- 786
Query: 1374 APAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA--- 1430
+ + P C RC EC G+ G DC +++ +C++
Sbjct: 787 -THNTNDCNPLPCYNGGICVDGVNWFRC--EC---APGFAGPDCRINID----ECQSSPC 836
Query: 1431 ---LQCWRLFNNSRCD--PACSSPAC---LYDNFDCHAGGRERTCNPVYEKYC-ADHFAD 1481
C N RC P + P C + C + G + + C + D
Sbjct: 837 AYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLD 896
Query: 1482 GRCDQGCNTEECGWDGLDCASEVPALLAR 1510
GR D C+ CGW A + AL A+
Sbjct: 897 GRRD--CSKVWCGWKPCLLAGQPEALSAQ 923
Score = 207 bits (527), Expect = 1e-52
Identities = 110/287 (38%), Positives = 143/287 (49%), Gaps = 18/287 (6%)
Query: 34 AGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGV 92
AGPG P C GRC P +C+C G+ G C D C PC G
Sbjct: 593 AGPGM--PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 650
Query: 93 CQSSVVAGTARFSCRCPRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 151
C V A F C CP G+ G C P+ CL PC RC F C+C G++
Sbjct: 651 CIDEVDA----FRCFCPSGWEGELCDTNPNDCLPDPCHSRGRC-YDLVNDFYCACDDGWK 705
Query: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRN 208
G++C S +C C +GGTC ++ +FRC CP G+ G C +N + C P+PC N
Sbjct: 706 GKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS--CLPNPCVN 762
Query: 209 GGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG 268
GGTC SG ++ C C G+EG+ C N +DC C NGG CVDGVN + C+C P + G
Sbjct: 763 GGTCVGSG-ASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAG 821
Query: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI 315
C ++DECQ P C G TC + + G+ C C G G C + I
Sbjct: 822 PDCRINIDECQSSP--CAYGATCVDEINGYRCSCPPGRAGPRCQEVI 866
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 462 bits (1190), Expect = e-129
Identities = 489/1637 (29%), Positives = 603/1637 (36%), Gaps = 318/1637 (19%)
Query: 24 VRALPLLLLLAGP-GAAAPP-----CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ 77
V AL LLLL A P GA+ PP G P + L R C+ +
Sbjct: 15 VLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQPCV-------QALS 67
Query: 78 LEDPCHSGPCAGRGVCQS------------SVVAGTARFSCRCPRGF-RGPDCS--LPDP 122
P C + C V AR RC RG+ + PD L
Sbjct: 68 HTVPVWKAGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAE 127
Query: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP-CRHGGTCLNTPGSF 181
C +S C HG RC P C CPPG+QG C+ DVDECR C+H C+NTPGS+
Sbjct: 128 CSASLCFHGGRCV--PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQH--RCVNTPGSY 183
Query: 182 RCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT---YDCACLPGFE----GQNCE 234
C+C G+ + NGG LT + C C PGF+ G++C
Sbjct: 184 LCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC- 242
Query: 235 VNVDDCPGHR--CLNGGTCVDGVNTYNCQCPPEWT--GQFCTEDVDECQLQPNACHNGGT 290
V C C++ V G+ C + G+ C EDVDEC C +G
Sbjct: 243 VRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKAC-EDVDECAAGLAQCAHG-- 299
Query: 291 CFNTLGGHSCVCVNGWT----GESCSQ------NIDDCATAVCFHGATCHDRVASFYCAC 340
C NT G CVC G+ G C + N + C HG C A C C
Sbjct: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHG--CSHTSAGPLCTC 357
Query: 341 PMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF---TGGACDQDVD 393
P G C D C +PC + +C NP G C C G+ G +DVD
Sbjct: 358 PRGYELDTDQRTCIDVDDCADSPCCQQ-VCTNNP--GGYECGCYAGYRLSADGCGCEDVD 414
Query: 394 ECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQF 453
EC+ CEH C N GSF C C GY R D C P LD F
Sbjct: 415 ECASSRGGCEH--HCTNLAGSFQCSCEAGY---RLHEDRRGC--SPLEEPMVDLDGELPF 467
Query: 454 T------CICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLD 507
+ + + D+ + + G + C G C L
Sbjct: 468 VRPLPHIAVLQDELPQLFQDDDVGADEEEAELRG----EHTLTEKFVCLDDSFGHDCSLT 523
Query: 508 VDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFS 567
D+C RNG C+ DG C C EG+ G +C+ + C PD SFS
Sbjct: 524 CDDC-----RNGGTCLLGLDG--CDCPEGWTGLICN---ETCPPDTFGKN------CSFS 567
Query: 568 CACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
C+C G T C+S CR P G C D CP G G +C + CA+
Sbjct: 568 CSCQNGGT---CDSVTGACRCPPGVSGTNCED-------GCPKGYYGKHCRKKCN-CANR 616
Query: 628 PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP-CGEGGSCV-------DGENGF 679
G C C+C PG G C++ A P C E CV D +G
Sbjct: 617 ----GRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDG- 669
Query: 680 RCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACE 739
C C G C P C P G C G G RC + C
Sbjct: 670 SCSCKAGFRGERCQAECELGYFGPGCWQAC-TCPVGVACDSVSGECGKRCPAGFQGEDC- 727
Query: 740 SQPCRAG-------GTCSSDGMGFH-----CTCPPGVQGRQCELLSP-------CTP--N 778
Q C G +CS G H C CPPG G CE P C
Sbjct: 728 GQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICP 787
Query: 779 PCEHGGRCESAPGQ---LPV-----CS--CPQGWQGPRCQQDVDECAGPAPCGPH-GICT 827
C+H RC+ G LP C CP GW GP CQ CA C P G C+
Sbjct: 788 ACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCS-CANDGHCHPATGHCS 846
Query: 828 NLAG--SFSC--TCHGGYTGPSCDQDINDCDPNPCLNG-GSCQDGVGSFSCSCLPGFAGP 882
G FSC C G+ GP C N C G GSC D + C C G+ GP
Sbjct: 847 CAPGWTGFSCQRACDTGHWGPDCSHPCN------CSAGHGSC-DAISGL-CLCEAGYVGP 898
Query: 883 RCARDVDECLSNP-------CGPGTCTDHVASFTCTCPPGYGGFHCEQDLP------DC- 928
RC + + P C G DHV+ CTCP G+ G CE P DC
Sbjct: 899 RCEQQCPQGHFGPGCEQRCQCQHGAACDHVSG-ACTCPAGWRGTFCEHACPAGFFGLDCR 957
Query: 929 SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP----------CLHGGVCS 978
S +C G C D VN SCLC G G C A+ C + C +G C
Sbjct: 958 SACNCTAGAAC-DAVNG-SCLCPAGRRGPRC---AETCPAHTYGHNCSQACACFNGASCD 1012
Query: 979 AAHPGFRCTCLESFTGPQCQTLV------DWCSRQP-CQNGGRCVQTGAYCLCPPGWSGR 1031
H +C C + GP C D C CQNGG C +C CP GW+G
Sbjct: 1013 PVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGL 1070
Query: 1032 LCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL-- 1089
C+ LP R+ A G R C GG C + + C+CP G TG C+ PCL
Sbjct: 1071 ACEKECLP-RDVRA--GCRHSGGCLNGGLC--DPHTGRCLCPAGWTGDKCQ---SPCLRG 1122
Query: 1090 ------AQ--PCQHGGTCRGYMGGYMCECLPGYNGDNCED-----DVDECASQPCQHGG- 1135
AQ C G C G C C PG+ G CE E +Q CQ G
Sbjct: 1123 WFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGE 1180
Query: 1136 --SCIDLVARYLCSCPPGTLGVLCEINEDDCGP---GPPLDSGPRCLHNGTCVDLVGGFR 1190
+C A CSC G G C + C P GP + CL+ G+C G
Sbjct: 1181 NPACHP--ATGTCSCAAGYHGPSC---QQRCPPGRYGPGCEQLCGCLNGGSCDAATGA-- 1233
Query: 1191 CTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ----DPGGGFRCLCHAGFSGPRCQTV 1246
C CP G+ G C + R G + H C Q DP G CLC G +G RC+
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGP-NCTHVCGCGQGAACDPVTG-TCLCPPGRAGVRCERG 1291
Query: 1247 LSP------CE-SQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE------RVARSC 1293
CE + C++GG C S G +C C + G CE R +C
Sbjct: 1292 CPQNRFGVGCEHTCSCRNGGLCHASNG-------SCSCGLGWTGRHCELACPPGRYGAAC 1344
Query: 1294 R-ELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASC-AAAPCLHGGSCR 1351
E C C+ P C C PG G +C PPG A C C HG C
Sbjct: 1345 HLECSCHNNSTCE--PATGTCRCGPGFYGQACEH--PCPPGFHGAGCQGLCWCQHGAPCD 1400
Query: 1352 PAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCG 1411
P RC C G+ G CE EP C QRCD + +P C
Sbjct: 1401 PIS----GRCLCPAGFHGHFCERGC-------EPGSFGEGCH-----QRCDCDGGAP-CD 1443
Query: 1412 WDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVY 1471
G C G C L C R + P+C+ C GG C+PV
Sbjct: 1444 PVTGLCLCPPGRSGATCN-LDCRR----GQFGPSCT--------LHCDCGG-GADCDPVS 1489
Query: 1472 -EKYCADHFADGRCDQG 1487
+ +C D + C +G
Sbjct: 1490 GQCHCVDGYMGPTCREG 1506
Score = 171 bits (433), Expect = 8e-42
Identities = 208/758 (27%), Positives = 269/758 (35%), Gaps = 167/758 (22%)
Query: 852 DCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCG-PGTCTDHVASFTC 910
+C + C +GG C G C C PGF GPRC DVDEC ++ G C + S+ C
Sbjct: 127 ECSASLCFHGGRCVPGSAQ-PCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLC 185
Query: 911 TCPPGYGGFHCEQDLPDC-SPSSCF--NGGT---CVD-GVNSFSCLCRPGY----TGAHC 959
C P GF D C + +SC NGG CV + C CRPG+ G HC
Sbjct: 186 ECKP---GFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 242
Query: 960 QHEADPCLSR--PCLHGGVCSAAHPGFRCTCLESF----TGPQCQTLVDWCSRQPCQNGG 1013
+ PC +R C+H C RC C + G C+ VD C+ Q
Sbjct: 243 VRRS-PCANRNGSCMHR--CQVVRGLARCECHVGYQLAADGKACED-VDECAAGLAQCAH 298
Query: 1014 RCVQT-GAY-CLCPPGW----SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
C+ T G++ C+C G+ GR C +I + + C+A S
Sbjct: 299 GCLNTQGSFKCVCHAGYELGADGRQC-----------YRIEMEIVNSCEANNGGCSHGCS 347
Query: 1068 H-----YCVCPEG---RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY--NGD 1117
H C CP G T +VD C PC C GGY C C GY + D
Sbjct: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQ-QVCTNNPGGYECGCYAGYRLSAD 406
Query: 1118 NCE-DDVDECASQ--PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGP------ 1168
C +DVDECAS C+H C +L + CSC G ++ED G P
Sbjct: 407 GCGCEDVDECASSRGGCEH--HCTNLAGSFQCSCEAG-----YRLHEDRRGCSPLEEPMV 459
Query: 1169 ----------PL-------DSGPRCLHNGTC------VDLVGGFRCT----CPPGYTGLR 1201
PL D P+ + +L G T C G
Sbjct: 460 DLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHD 519
Query: 1202 CEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP------CE-SQP 1254
C ++CR+G CL G C C G++G C P C S
Sbjct: 520 CSLTCDDCRNGG-------TCLLGLDG---CDCPEGWTGLICNETCPPDTFGKNCSFSCS 569
Query: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE-RVARSCRELQCPVGVPCQQTPRGPR- 1312
CQ+GG C +T C C G CE + C C R R
Sbjct: 570 CQNGGTC-------DSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRL 622
Query: 1313 ---CACPPGLSGPSCRSFPGSPPGASNASCA-AAPCL--HGGSCRPAPLAPFFRCACAQG 1366
C C PGL G C PP A C+ C+ H SC + C+C G
Sbjct: 623 YGACLCDPGLYGRFCHL--TCPPWAFGPGCSEECQCVQPHTQSCDKRDGS----CSCKAG 676
Query: 1367 WTGPRCEAPAA----APEVSEEPRCP-RAACQAKRGD--QRCDRECNSPGCGWD------ 1413
+ G RC+A P + CP AC + G+ +RC CG +
Sbjct: 677 FRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTF 736
Query: 1414 GGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFD----------CHAGGR 1463
G +CS S C C + RC P + C D + C A
Sbjct: 737 GVNCSSSC-----SCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQH 791
Query: 1464 ERTCNP-VYEKYCADHFADGRCDQGCNTEECGWDGLDC 1500
C+P C F RC C GW G C
Sbjct: 792 AARCDPETGACLCLPGFVGSRCQDVC---PAGWYGPSC 826
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 461 bits (1186), Expect = e-129
Identities = 487/1734 (28%), Positives = 677/1734 (39%), Gaps = 432/1734 (24%)
Query: 91 GVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
G C++++ F CRC GF +C+ D C SP G+ V G F C C
Sbjct: 1087 GKCRNTI----GSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECEC 1142
Query: 147 PPGYQG-----RSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP- 200
GY+ ++C D+DEC GGTC+NT GSF+C CP G+ V
Sbjct: 1143 FEGYESGFMMMKNCM-DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDI 1201
Query: 201 --CAPSP--CRNGGTCRQSGDLTYDCACLPGFEG----QNCEVNVDDCPGHRCLNGGT-- 250
C+ S CRNG G TY C+C PG++ Q C ++D+C +NGG
Sbjct: 1202 NECSLSDNLCRNGKCVNMIG--TYQCSCNPGYQATPDRQGC-TDIDEC---MIMNGGCDT 1255
Query: 251 -CVDGVNTYNCQCPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNG 305
C + +Y C C + G+ C D+DEC+ P+ C +GG C N G + C+C +G
Sbjct: 1256 QCTNSEGSYECSCSEGYALMPDGRSCA-DIDECENNPDIC-DGGQCTNIPGEYRCLCYDG 1313
Query: 306 WTG----ESCSQ-NIDDCATAVCFHGATCHDRVASFYCACPMG---KTGLL-CHLDDACV 356
+ ++C N D + +C G C + SF C C +G K G C D C
Sbjct: 1314 FMASMDMKTCIDVNECDLNSNICMFGE-CENTKGSFICHCQLGYSVKKGTTGCTDVDECE 1372
Query: 357 --SNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQG 413
++ C A C P G C+C G+ G G D+DECS G + C +CVNT G
Sbjct: 1373 IGAHNCDMHASCLNIP--GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG 1430
Query: 414 SFLCQCGRGYTGP--RCETDVNECLS--GPCRNQATCLDRIGQFTCICMAGFT----GTY 465
S+ C C G+TG C +DV+EC C N CL+ G + C C GFT
Sbjct: 1431 SYRCACSEGFTGDGFTC-SDVDECAENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRS 1488
Query: 466 CEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECAS-TPCRNGA 520
C+ DIDEC G C + F C C G+ +G C D+DECA C NG
Sbjct: 1489 CQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGL 1546
Query: 521 KCVDQPDGYECRCAEGFE----GTLC-DRNVDDC----SPDPCHHGRCVD----GIASFS 567
CV+ P YEC C F+ G C D V +C P C G++ S
Sbjct: 1547 -CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSS 1605
Query: 568 CACAPGYT-GTRCES-----------------------------QVDECRSQP--CRHGG 595
C C+ G G CE+ +DEC+ P C+ GG
Sbjct: 1606 CCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQ-GG 1664
Query: 596 KCLDLVDKYLCRCPSG-----TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPG 648
C++ + C CP G T + CE +ID+C ++P C G C + + Y C+C P
Sbjct: 1665 NCINTFGSFQCECPQGYYLSEDTRI-CE-DIDECFAHPGVCGPGTCYNTLGNYTCICPPE 1722
Query: 649 FTGPLCNVEINECASSPCGEGGSCVDGENGFRC--LCPPGSLPPLCLPP-------SHPC 699
+ +++N + C NG C P +C + PC
Sbjct: 1723 Y------MQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPC 1776
Query: 700 AHEPCSHGICYDAPG--GFRCVCE--PGWS-GPRCSQSLARDACESQP-CRAGGTCSSDG 753
EPC PG F+ +C PG++ +++ D C+ P A G C +
Sbjct: 1777 --EPC------PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQI 1828
Query: 754 MGFHCTCPPGVQGRQ----CELLSPCT--PNPCEHGGRCESAPGQLPVCSCPQGWQ-GPR 806
F C CP G CE + C+ N C+ C ++PG C C G++ P
Sbjct: 1829 GSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYR-CECAAGFKLSPN 1887
Query: 807 -CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ----DINDCDPNPCLNG 861
D +EC HG+C +L GS+ C CH G+ S DQ D+++C+ +PC N
Sbjct: 1888 GACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA-SQDQTMCMDVDECERHPCGN- 1945
Query: 862 GSCQDGVGSFSCSCLPGF--AGPRCARDVDECLS---NPCGPGTCTDHVASFTCTCPPGY 916
G+C++ VGS++C C PGF D+DEC S C G C + + SF C C GY
Sbjct: 1946 GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGY 2005
Query: 917 ----GGFHCEQDLPDC--SPSSCFNGGTCVDGVNSFSCLCRPGY--TGAHC----QHEAD 964
G +C D +C P SC + GTC + SF C+C PGY +C + + D
Sbjct: 2006 ELTPDGKNC-IDTNECVALPGSC-SPGTCQNLEGSFRCICPPGYEVKSENCIDINECDED 2063
Query: 965 PCLSRPCLHGGVCSAAHPGFRCTCLESF----TGPQC-QTLVDWCSRQPCQNGGRCV--- 1016
P + CL G C+ GF+C C F G +C T +C G+C
Sbjct: 2064 PNI---CLFGS-CTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTN--FENGKCSVPK 2117
Query: 1017 ---QTGAYCLCP----PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAG----------- 1058
T A C C GW PC V + LC G
Sbjct: 2118 AFNTTKAKCCCSKMPGEGWGD--------PCELCPKDDEVAFQDLCPYGHGTVPSLHDTR 2169
Query: 1059 ---------------GQCVDEDSSHYCVCPEG----RTGSHCEQEVDPCLAQPCQHGGTC 1099
GQC++ D S C CP G TG C + + PC + GTC
Sbjct: 2170 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGN-GTC 2228
Query: 1100 RGYMGGYMCECLPGYNGD---NCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVL 1156
+G + C C G+ NCE D++ECA P C++ Y C+CP +G
Sbjct: 2229 TNVIGSFECNCNEGFEPGPMMNCE-DINECAQNPLLCAFRCMNTFGSYECTCP---IGYA 2284
Query: 1157 CEINEDDCGPGPPLDSGPRCLHN-----GTCVDLVGGFRCTCPPGYT----GLRCEADIN 1207
++ C LD LH+ C +L+G F C CPPG G C D N
Sbjct: 2285 LREDQKMC---KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDEN 2340
Query: 1208 ECRS--GACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRC-------------QTVLS 1248
ECR+ G C + + G +RC C+ GF SG C QT+
Sbjct: 2341 ECRTKPGICENGRCVNII----GSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQ 2396
Query: 1249 PC--------ESQPCQHGG-----QCRPSPGPGGGL------------------------ 1271
+S+ C GG QC P PG
Sbjct: 2397 MASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVM 2456
Query: 1272 --------------TFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRC 1313
+F C C + G C + C + P C+ T +C
Sbjct: 2457 PNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDL-DECSQSPKPCNYICKNTEGSYQC 2515
Query: 1314 ACPPGL----SGPSCRSFP----------------------GSPPG--------ASNASC 1339
+CP G G +C+ PPG N C
Sbjct: 2516 SCPRGYVLQEDGKTCKDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNEC 2575
Query: 1340 AAAPCLHG--GSCRPAPLAPFFRCACAQGW----TGPRCEAPAAAPEVSEEPRCPRAACQ 1393
+ P L G G C+ P + F C C +G+ TG CE E RC + CQ
Sbjct: 2576 GSQPSLCGAKGICQNTPGS--FSCECQRGFSLDATGLNCE---DVDECDGNHRC-QHGCQ 2629
Query: 1394 AKRGDQRCDRECNSPGC--------GW----DGGDCSLSVGDPWRQCEALQCWRLFNNSR 1441
G RC GC W D +CS +P C + C+ + +
Sbjct: 2630 NILGGYRC-------GCPQGYIQHYQWNQCVDENECS----NP-NACGSASCYNTLGSYK 2677
Query: 1442 CDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGW 1495
C AC S +D F C+ V E C+ + C+ GC+ E G+
Sbjct: 2678 C--ACPS-GFSFDQF-------SSACHDVNE--CSS--SKNPCNYGCSNTEGGY 2717
Score = 451 bits (1161), Expect = e-126
Identities = 448/1522 (29%), Positives = 619/1522 (40%), Gaps = 274/1522 (18%)
Query: 43 CLDGSPCAN------GGRCTQLPSREAACLCPPGWVG----ERCQLEDPC--HSGPCAGR 90
C D C N GG+CT +P E CLC G++ + C + C +S C
Sbjct: 1281 CADIDECENNPDICDGGQCTNIPG-EYRCLCYDGFMASMDMKTCIDVNECDLNSNICMF- 1338
Query: 91 GVCQSSVVAGTARFSCRCPRGFR----GPDCSLPDPCL--SSPCAHGARCSVGPDGRFLC 144
G C+++ F C C G+ C+ D C + C A C P G F C
Sbjct: 1339 GECENT----KGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP-GSFKC 1393
Query: 145 SCPPGYQGRSCRS-DVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGP--LCENPAVP 200
SC G+ G + D+DEC G C C+NTPGS+RC C G+TG C +
Sbjct: 1394 SCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSD-VDE 1452
Query: 201 CAPSP--CRNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDG 254
CA + C NG G Y C C GF + ++C+ ++D+C GTC +
Sbjct: 1453 CAENINLCENGQCLNVPG--AYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNL 1509
Query: 255 VNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW---- 306
++C C + TG CT D+DEC P C NG C NT G + C C +
Sbjct: 1510 PGMFHCICDDGYELDRTGGNCT-DIDECA-DPINCVNG-LCVNTPGRYECNCPPDFQLNP 1566
Query: 307 TGESCSQN-IDDCATAVCFHG---ATCHDR----VASFYCACPMGKTG------------ 346
TG C N + +C G +C+ V+ C C +GK
Sbjct: 1567 TGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNS 1626
Query: 347 ----LLCHLDDACVSNP----------CHE-DAICDT-NPVN--GRAICTCPPGF---TG 385
LC + NP C E +C N +N G C CP G+
Sbjct: 1627 TEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSED 1686
Query: 386 GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG---------------------RGYT 424
+D+DEC C G C NT G++ C C R Y
Sbjct: 1687 TRICEDIDECFAHPGVCGP-GTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYN 1745
Query: 425 GPRCETDVNECLSGPCRNQATCLDRIGQ----------------FTCIC--MAGFT---G 463
G CE NE + C +G+ F IC + GFT
Sbjct: 1746 GTTCE---NELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIH 1802
Query: 464 TYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFSGSTCQL---DVDECASTP--C 516
T VDIDEC+ P C NG VC +++ F C CP+GFS + L D+DEC++ C
Sbjct: 1803 TGKAVDIDECKEIPGICANG-VCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLC 1861
Query: 517 RNGAKCVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAP 572
+ A C++ P Y C CA GF+ G DRN P+ C HG CVD S+ C C
Sbjct: 1862 QRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHN 1921
Query: 573 GYTGTRCESQ---VDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCAS- 626
G+ ++ ++ VDEC PC +G C + V Y C C G T N ++ID+C+S
Sbjct: 1922 GFKASQDQTMCMDVDECERHPCGNG-TCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSF 1980
Query: 627 --NPCTFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSPCG-EGGSCVDGENGF 679
C G C + I + C+C G+ G C ++ NEC + P G+C + E F
Sbjct: 1981 FGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVALPGSCSPGTCQNLEGSF 2039
Query: 680 RCLCPPGS--LPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGW----SGPRC-- 729
RC+CPPG C+ + C +P C G C + PGGF+C+C PG+ +G RC
Sbjct: 2040 RCICPPGYEVKSENCIDINE-CDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFD 2098
Query: 730 -SQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ-GRQCELLSPCTPNPCEHGGRCE 787
QS E+ C ++ C+ PG G CEL + C
Sbjct: 2099 TRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPK--DDEVAFQDLCP 2156
Query: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TG 843
G +P ++DV+EC +G C N GSF C C GY TG
Sbjct: 2157 YGHGTVPSLH--------DTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTG 2208
Query: 844 PSCDQDINDCD-PNPCLNGGSCQDGVGSFSCSCLPGFA-GPRC-ARDVDECLSNP--CGP 898
C D ++C NPC NG +C + +GSF C+C GF GP D++EC NP C
Sbjct: 2209 VRC-VDTDECSIGNPCGNG-TCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCA- 2265
Query: 899 GTCTDHVASFTCTCPPGYGGFHCEQ---DLPDCSPS--SCFNGGT-CVDGVNSFSCLCRP 952
C + S+ CTCP GY ++ DL +C+ C + G C + + +F C+C P
Sbjct: 2266 FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
Query: 953 GYT----GAHCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESF----TGPQCQTLVDW 1003
G G C E + C ++P + G C +RC C E F +G +C
Sbjct: 2326 GMARRPDGEGCVDENE-CRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLD---- 2380
Query: 1004 CSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD 1063
+RQ G C +C S R +S C + G + E LC G
Sbjct: 2381 -NRQ-----GLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCE-LCPLPGT--- 2430
Query: 1064 EDSSHYCVCPEGRTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGY----NGD 1117
+ + +CP G + +++D C P C +G C MG + C C GY +G
Sbjct: 2431 --AQYKKICPHGPGYTTDGRDIDECKVMPNLCTNG-QCINTMGSFRCFCKVGYTTDISGT 2487
Query: 1118 NCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCL 1177
+C D +DEC+ P C + Y CSCP G + ++D LD
Sbjct: 2488 SCID-LDECSQSPKPCNYICKNTEGSYQCSCPRGY------VLQEDGKTCKDLDECQTKQ 2540
Query: 1178 HNGT--CVDLVGGFRCTCPPGYTGLRCEA-DINECRSGACHAAHTRDCLQDPGGGFRCLC 1234
HN CV+ +GGF C CPPG+T D NEC S C P G F C C
Sbjct: 2541 HNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTP-GSFSCEC 2599
Query: 1235 HAGFS----GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPF-----WGPR 1285
GFS G C+ V + CQHG C+ G + C C Q + W
Sbjct: 2600 QRGFSLDATGLNCEDVDECDGNHRCQHG--CQNILG-----GYRCGCPQGYIQHYQWNQC 2652
Query: 1286 CERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCL 1345
+ C C T +CACP SG S F + + S + PC
Sbjct: 2653 VDE--NECSNPNACGSASCYNTLGSYKCACP---SGFSFDQFSSACHDVNECSSSKNPCN 2707
Query: 1346 HGGSCRPAPLAPFFRCACAQGW 1367
+G S + C C G+
Sbjct: 2708 YGCSNTEGG----YLCGCPPGY 2725
Score = 439 bits (1129), Expect = e-122
Identities = 472/1702 (27%), Positives = 664/1702 (39%), Gaps = 381/1702 (22%)
Query: 43 CLD-----GSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHS-GPCAGRGV-CQS 95
C+D +PC NG C P C C G+ +R + C C GV C++
Sbjct: 533 CIDVDECTSNPCTNGD-CVNTPG-SYYCKCHAGF--QRTPTKQACIDIDECIQNGVLCKN 588
Query: 96 SVVAGT-ARFSCRCPRGFR----GPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY 150
T F C C GF G +C D C ++ C + DG F C C PG+
Sbjct: 589 GRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNGMC-INEDGSFKCICKPGF 647
Query: 151 ----QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAG------------------ 188
GR C +DVDEC+ C +G C+N+ GSFRC CP G
Sbjct: 648 VLAPNGRYC-TDVDECQTPGICMNGH-CINSEGSFRCDCPPGLAVGMDGRVCVDTHMRST 705
Query: 189 -------------YTGPL------CENP----AVPCAPSPCRNG----GTCRQSGDLTYD 221
+ G + C NP PC P P +N G C +T D
Sbjct: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVD 765
Query: 222 CACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC----PPEWTGQFCTEDVDE 277
G + C ++ D C G C + +Y C C P+ +G+ C D+DE
Sbjct: 766 -----GRDINECALDPDICAN------GICENLRGSYRCNCNSGYEPDASGRNCI-DIDE 813
Query: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQNIDDCATAVCFHGATCHDRV 333
C + C NG C NT G +SC C G+ E+C ++I++C + C +GA C + +
Sbjct: 814 CLVNRLLCDNG-LCRNTPGSYSCTCPPGYVFRTETETC-EDINECESNPCVNGA-CRNNL 870
Query: 334 ASFYCACPMGK----TGLLC--HLDDACVSNPCHEDAICDTNPVNGRAI----------- 376
SF C C G TGL+C L C N +D+ C+ N +NG +
Sbjct: 871 GSFNCECSPGSKLSSTGLICIDSLKGTCWLNI--QDSRCEVN-INGATLKSECCATLGAA 927
Query: 377 -----------CTCPPGFTG--GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY 423
CP G G +DV+EC + C + GRCVN++GSF C+C G
Sbjct: 928 WGSPCERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGL 986
Query: 424 T----GPRC-ETDVNECLSGPCRNQATCLDRI-GQF---TCICMAGFT-GTYCEVDIDEC 473
T G C + + +C ++ C+ + G+F C C G GT CE EC
Sbjct: 987 TLDGTGRVCLDIRMEQCYLK--WDEDECIHPVPGKFRMDACCCAVGAAWGTECE----EC 1040
Query: 474 QSSPCVNGGVCKDRVNGFSCTCPSG---------FSGSTCQLDVDECASTP--CRNGAKC 522
K + CP G +G D++EC + P C G KC
Sbjct: 1041 P----------KPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYG-KC 1089
Query: 523 VDQPDGYECRCAEGFEGTLCDRN---VDDC--SPDPCHHGRCVDGIASFSCACAPGYTG- 576
+ ++CRC GF + +RN +D+C SPD C G CV+ SF C C GY
Sbjct: 1090 RNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESG 1149
Query: 577 ----TRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCA- 625
C +DEC P CR GG C++ + C CP G + +C V+I++C+
Sbjct: 1150 FMMMKNC-MDIDECERNPLLCR-GGTCVNTEGSFQCDCPLGHELSPSREDC-VDINECSL 1206
Query: 626 -SNPCTFGVCRDGINRYDCVCQPGFTGPLCN---VEINECASSPCGEGGSCVDGENGFRC 681
N C G C + I Y C C PG+ +I+EC G C + E + C
Sbjct: 1207 SDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYEC 1266
Query: 682 LCPPGSLPPLCLPPSHPCAH--------EPCSHGICYDAPGGFRCVCEPGWSGPRCSQS- 732
C G +P CA + C G C + PG +RC+C G+ ++
Sbjct: 1267 SCSEGYA---LMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1323
Query: 733 LARDACE--SQPCRAGGTCSSDGMGFHCTCPPGVQGRQ----CELLSPCT--PNPCEHGG 784
+ + C+ S C G C + F C C G ++ C + C + C+
Sbjct: 1324 IDVNECDLNSNICMFG-ECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHA 1382
Query: 785 RCESAPGQLPVCSCPQGW--QGPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGY 841
C + PG CSC +GW G +C D+DEC+ G C + C N GS+ C C G+
Sbjct: 1383 SCLNIPGSFK-CSCREGWIGNGIKCI-DLDECSNGTHQCSINAQCVNTPGSYRCACSEGF 1440
Query: 842 TGPSCD-QDINDCDPNPCL-NGGSCQDGVGSFSCSCLPGF---AGPRCARDVDEC-LSNP 895
TG D+++C N L G C + G++ C C GF + R +D+DEC N
Sbjct: 1441 TGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI 1500
Query: 896 CGPGTCTDHVASFTCTCPPGYG----GFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLC 950
C GTC + F C C GY G +C D+ +C+ P +C NG CV+ + C C
Sbjct: 1501 CVFGTCNNLPGMFHCICDDGYELDRTGGNCT-DIDECADPINCVNG-LCVNTPGRYECNC 1558
Query: 951 RPGY----TGAHC-QHEADPCLSR--PCLHGGVCSAAHPGF---RCTCLESFTGPQCQTL 1000
P + TG C + C + P G + G R +C C
Sbjct: 1559 PPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCC-------CSLG 1611
Query: 1001 VDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSL-----PCREAAAQIGVRLEQLC 1055
W + PC+ T Y LCP G R I + C+E L LC
Sbjct: 1612 KAWGN--PCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQE--------LPGLC 1661
Query: 1056 QAGGQCVDEDSSHYCVCPEGRTGSH----CEQEVDPCLAQPCQHG-GTCRGYMGGYMCEC 1110
Q GG C++ S C CP+G S CE ++D C A P G GTC +G Y C C
Sbjct: 1662 Q-GGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGPGTCYNTLGNYTCIC 1719
Query: 1111 LP---------------------GYNGDNCEDD---------------VDECASQPCQHG 1134
P YNG CE++ V + ++PC+
Sbjct: 1720 PPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPC 1779
Query: 1135 GSCIDLVARYLCSCPPG---TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1191
+ + +C PG + ++ D+C P + + NG C++ +G FRC
Sbjct: 1780 PTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGICA------NGVCINQIGSFRC 1833
Query: 1192 TCPPGYTG----LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS-GPRCQTV 1246
CP G++ L CE DI+EC +G DC+ PG +RC C AGF P V
Sbjct: 1834 ECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGS-YRCECAAGFKLSPNGACV 1891
Query: 1247 -LSPCESQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARS---CRELQCPV 1300
+ C P C HG C G ++ C C F + + + C C
Sbjct: 1892 DRNECLEIPNVCSHG-LCVDLQG-----SYQCICHNGFKASQDQTMCMDVDECERHPCGN 1945
Query: 1301 GVPCQQTPRGPRCACPPG---------LSGPSCRSFPGSPPGASNASCAAAPCLHG-GSC 1350
G C+ T C C PG L C SF G C C + GS
Sbjct: 1946 GT-CKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQV-------CRNGRCFNEIGS- 1996
Query: 1351 RPAPLAPFFRCACAQGWT----GPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC----D 1402
F+C C +G+ G C V+ C CQ G RC
Sbjct: 1997 --------FKCLCNEGYELTPDGKNCIDTNEC--VALPGSCSPGTCQNLEGSFRCICPPG 2046
Query: 1403 RECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGG 1462
E S C D +C DP C C +C C L DN
Sbjct: 2047 YEVKSENC-IDINECD---EDP-NICLFGSCTNTPGGFQC--LCPPGFVLSDN------- 2092
Query: 1463 RERTCNPVYEKYCADHFADGRC 1484
R C + +C +F +G+C
Sbjct: 2093 -GRRCFDTRQSFCFTNFENGKC 2113
Score = 422 bits (1085), Expect = e-117
Identities = 453/1713 (26%), Positives = 643/1713 (37%), Gaps = 339/1713 (19%)
Query: 36 PGAAAPP----CLDGSPCANGGRCTQ----LPSREAACLCPPGWV----GERC---QLED 80
PG P C D C G C C CPPG G C +
Sbjct: 645 PGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRS 704
Query: 81 PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGAR------- 133
C+ G +GVC + C C PD +PC P + A
Sbjct: 705 TCYGG--IKKGVCVRPFPGAVTKSECCCAN----PDYGFGEPCQPCPAKNSAEFHGLCSS 758
Query: 134 -------------CSVGPD-----------GRFLCSCPPGYQ----GRSCRSDVDECRVG 165
C++ PD G + C+C GY+ GR+C D+DEC V
Sbjct: 759 GVGITVDGRDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVN 817
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAPSPCRNGGTCRQSGDLTYD 221
G C NTPGS+ C CP GY CE+ C +PC NG G +
Sbjct: 818 RLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED-INECESNPCVNGACRNNLGSFNCE 876
Query: 222 CA-----------CLPGFEGQNCEVNVDDCPGHRCLNGGTCVD----------GVNTYNC 260
C+ C+ +G C +N+ D +NG T G C
Sbjct: 877 CSPGSKLSSTGLICIDSLKG-TCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERC 935
Query: 261 Q----CP---PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQ 313
+ CP G C EDV+EC++ P C N G C N+ G C C G T + +
Sbjct: 936 ELDTACPRGLARIKGVTC-EDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGR 993
Query: 314 NIDDCATAVCF----HGATCHDRVASF---YCACPMGKT-GLLCHLDDACVSNPCHE-DA 364
D C+ H F C C +G G C + C E +
Sbjct: 994 VCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTEC---EECPKPGTKEYET 1050
Query: 365 ICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT 424
+C G TG +D++EC C + G+C NT GSF C+C G+
Sbjct: 1051 LCP----RGAGFANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFKCRCNSGFA 1105
Query: 425 ---GPRCETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCE----VDIDECQSS 476
R TD++EC +S C++ G F C C G+ + +DIDEC+ +
Sbjct: 1106 LDMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERN 1165
Query: 477 PCV-NGGVCKDRVNGFSCTCPSGFSGSTCQ---LDVDECASTP--CRNGAKCVDQPDGYE 530
P + GG C + F C CP G S + +D++EC+ + CRNG KCV+ Y+
Sbjct: 1166 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTYQ 1224
Query: 531 CRCAEGFEGTLCDRNVDDCSPDPCHHG----RCVDGIASFSCACAPGYT----GTRCESQ 582
C C G++ T + D +G +C + S+ C+C+ GY G C +
Sbjct: 1225 CSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-AD 1283
Query: 583 VDECRSQP-CRHGGKCLDLVDKYLCRCPSGTTG-----VNCEVNIDDCASNPCTFGVCRD 636
+DEC + P GG+C ++ +Y C C G +VN D SN C FG C +
Sbjct: 1284 IDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFGECEN 1343
Query: 637 GINRYDCVCQPGFT---GPLCNVEINEC--ASSPCGEGGSCVDGENGFRCLCPPG----S 687
+ C CQ G++ G +++EC + C SC++ F+C C G
Sbjct: 1344 TKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNG 1403
Query: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
+ + L H+ + C + PG +RC C G++G + S + E+ G
Sbjct: 1404 IKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTCSDVDECAENINLCENG 1463
Query: 748 TCSSDGMGFHCTC----PPGVQGRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGW 802
C + + C C P R C+ + C+ N C G C + PG C C G+
Sbjct: 1464 QCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVF-GTCNNLPGMFH-CICDDGY 1521
Query: 803 Q----GPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC 853
+ G C D+DECA P C +G+C N G + C C + TG C D + +C
Sbjct: 1522 ELDRTGGNC-TDIDECADPINC-VNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNC 1579
Query: 854 --DPNPCLNGG-SCQD----GVGSFSCSC------------------------LPGFAGP 882
P +G SC GV SC C PG G
Sbjct: 1580 YLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGF 1639
Query: 883 R------CARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDC--S 929
R D+DEC P C G C + SF C CP GY +D+ +C
Sbjct: 1640 RPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAH 1699
Query: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCL 989
P C GTC + + +++C+C P Y + H C+ + C ++ G C
Sbjct: 1700 PGVC-GPGTCYNTLGNYTCICPPEYMQVNGGHN---CMD---MRKSFCYRSYNGTTCENE 1752
Query: 990 ESFTGPQ----CQTLVDWCSRQPCQNGGRCVQTG-----AYCLCPPGW-----SGRLCDI 1035
F + C V +PC+ C G C PG+ +G+ DI
Sbjct: 1753 LPFNVTKRMCCCTYNVGKAWNKPCE---PCPTPGTADFKTICGNIPGFTFDIHTGKAVDI 1809
Query: 1036 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSH----CEQEVDPCL-- 1089
C+E + +C A G C+++ S C CP G + + CE ++D C
Sbjct: 1810 DE--CKE--------IPGIC-ANGVCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNG 1857
Query: 1090 AQPCQHGGTCRGYMGGYMCECLPGY--NGDNCEDDVDECASQP--CQHGGSCIDLVARYL 1145
CQ C G Y CEC G+ + + D +EC P C H G C+DL Y
Sbjct: 1858 DNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSH-GLCVDLQGSYQ 1916
Query: 1146 CSCPPGTLG----VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY--TG 1199
C C G +C ++ D+C P NGTC + VG + C C PG+ T
Sbjct: 1917 CICHNGFKASQDQTMC-MDVDECERHP--------CGNGTCKNTVGSYNCLCYPGFELTH 1967
Query: 1200 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRCQTVLSPCESQPC 1255
DI+EC S C + G F+CLC+ G+ G C + C + P
Sbjct: 1968 NNDCLDIDECSSFFGQVCRNGRCFNEI-GSFKCLCNEGYELTPDGKNCIDT-NECVALP- 2024
Query: 1256 QHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQ--------CPVGVPCQQT 1307
G C P +F C C P E + +C ++ C G C T
Sbjct: 2025 ---GSCSPGTCQNLEGSFRCICP-----PGYEVKSENCIDINECDEDPNICLFG-SCTNT 2075
Query: 1308 PRGPRCACPPG--LSGPSCRSFPGSP----PGASNASCAAAPCLHGGSCRPAPLAPFFRC 1361
P G +C CPPG LS R F N C+ + +C
Sbjct: 2076 PGGFQCLCPPGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKA---------KC 2126
Query: 1362 ACA----QGWTGPRCEAPAAAPEVSEEPRCPRA-ACQAKRGDQRCD-REC-NSPGCGWDG 1414
C+ +GW P CE EV+ + CP D R D EC SPG
Sbjct: 2127 CCSKMPGEGWGDP-CELCPKDDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGI-CSN 2184
Query: 1415 GDCSLSVGDPWRQCEALQCWRL-FNNSRCDPACSSPACLYDNFDCHAGG--RERTCNPV- 1470
G C + G +CE + L + RC D +C G TC V
Sbjct: 2185 GQCINTDGS--FRCECPMGYNLDYTGVRC----------VDTDECSIGNPCGNGTCTNVI 2232
Query: 1471 --YEKYCADHFADGRCDQGCNTEECGWDGLDCA 1501
+E C + F G + EC + L CA
Sbjct: 2233 GSFECNCNEGFEPGPMMNCEDINECAQNPLLCA 2265
Score = 397 bits (1019), Expect = e-110
Identities = 421/1534 (27%), Positives = 586/1534 (38%), Gaps = 339/1534 (22%)
Query: 60 SREAACLCPPGWVGERCQLED--PCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
SR C C G + C + C S C G C C+C +G+ G C
Sbjct: 125 SRPNMCTCSSGQISSTCGSKSIQQC-SVRCMNGGTCADD--------HCQCQKGYIGTYC 175
Query: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG--------EPCR 169
P + C +G RC +GP+ C+C G+ G C D R G + C+
Sbjct: 176 G--QPVCENGCQNGGRC-IGPNR---CACVYGFTGPQCERDY---RTGPCFTQVNNQMCQ 226
Query: 170 HGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFE 229
T + + C G CE P P PCR G +P
Sbjct: 227 GQLTGIVCTKTLCCATIGRAWGHPCE--MCPAQPQPCRRG--------------FIPNIR 270
Query: 230 GQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPP----EWTGQFCTEDVDECQLQP 282
C+ +VD+C PG GG C++ V ++ C+CP T Q C ED+DEC + P
Sbjct: 271 TGACQ-DVDECQAIPG--ICQGGNCINTVGSFECRCPAGHKQSETTQKC-EDIDECSIIP 326
Query: 283 NACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT-------CHDRVAS 335
C G C NT+G + CVC G+ + D T +CF G R+
Sbjct: 327 GICETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTK 385
Query: 336 FYCACPMGKTGLLCHLDDACVSNPCHE-DAIC-DTNPVNG-RAICTCPPGFTGG------ 386
C C G+ + + +AC E +C D P+ G PG TGG
Sbjct: 386 MQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPS 445
Query: 387 --------------------------------------------ACDQDVDECSIGANPC 402
+Q +D C AN C
Sbjct: 446 GNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLC 505
Query: 403 EHLGRCVNTQGSFLCQCGRGY---TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMA 459
+ GRC+ T S+ C+C GY C DV+EC S PC N C++ G + C C A
Sbjct: 506 LN-GRCIPTVSSYRCECNMGYKQDANGDC-IDVDECTSNPCTN-GDCVNTPGSYYCKCHA 562
Query: 460 GFTGTYCE---VDIDEC-QSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDEC 511
GF T + +DIDEC Q+ G C + F C C +GF G C +D DEC
Sbjct: 563 GFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDGKNC-VDHDEC 621
Query: 512 AST-PCRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDC-SPDPCHHGRCVDGIAS 565
+T C NG C+++ ++C C GF G C +VD+C +P C +G C++ S
Sbjct: 622 TTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGS 679
Query: 566 FSCACAPGY-TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP---SGTTGVNCEVNI 621
F C C PG G VD C +GG + K +C P + T C N
Sbjct: 680 FRCDCPPGLAVGMDGRVCVDTHMRSTC-YGG-----IKKGVCVRPFPGAVTKSECCCANP 733
Query: 622 DDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP--CGEGGSCVDGENGF 679
D PC ++ + +C G + +INECA P C G C + +
Sbjct: 734 DYGFGEPCQPCPAKNSA-EFHGLCSSGVGITVDGRDINECALDPDICA-NGICENLRGSY 791
Query: 680 RCLCPPGSLPPL----CLPPSHPCAHE-PCSHGICYDAPGGFRCVCEPGWSGPRCSQSLA 734
RC C G P C+ + C +G+C + PG + C C PG+ R
Sbjct: 792 RCNCNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVF-RTETETC 850
Query: 735 RD--ACESQPCRAGGTCSSDGMGFHCTCPPG---------------------VQGRQCE- 770
D CES PC G C ++ F+C C PG +Q +CE
Sbjct: 851 EDINECESNPC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEV 909
Query: 771 ------LLSPCTP-------NPCEHGGRCESAPGQLPVCSCPQGW---QGPRCQQDVDEC 814
L S C +PCE RCE +CP+G +G C +DV+EC
Sbjct: 910 NINGATLKSECCATLGAAWGSPCE---RCELD------TACPRGLARIKGVTC-EDVNEC 959
Query: 815 -AGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC----DPNPCLN---- 860
P C P+G C N GSF C C G TG C D + C D + C++
Sbjct: 960 EVFPGVC-PNGRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPG 1018
Query: 861 ---------------GGSCQD----GVGSFSCSCLPG---------FAGPRCARDVDECL 892
G C++ G + C G G +D++EC
Sbjct: 1019 KFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECK 1078
Query: 893 SNP--CGPGTCTDHVASFTCTCPPGYGGFHCEQ---DLPDC--SPSSCFNGGTCVDGVNS 945
+ P C G C + + SF C C G+ E+ D+ +C SP C G CV+ S
Sbjct: 1079 AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDECRISPDLC-GSGICVNTPGS 1137
Query: 946 FSCLCRPGYTGA-----HCQHEADPCLSRPCL-HGGVCSAAHPGFRCTC-LESFTGPQCQ 998
F C C GY +C + D C P L GG C F+C C L P +
Sbjct: 1138 FECECFEGYESGFMMMKNCM-DIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSRE 1196
Query: 999 TLVD--WCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQ 1053
VD CS C+NG G Y C C PG+ ++ P R+ I E
Sbjct: 1197 DCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGY-------QATPDRQGCTDID---EC 1246
Query: 1054 LCQAGG---QCVDEDSSHYCVCPEGRT----GSHCEQEVDPCLAQP--CQHGGTCRGYMG 1104
+ GG QC + + S+ C C EG G C ++D C P C GG C G
Sbjct: 1247 MIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-ADIDECENNPDICD-GGQCTNIPG 1304
Query: 1105 GYMCECLPGYNGD----NCEDDVDEC--ASQPCQHGGSCIDLVARYLCSCPPG---TLGV 1155
Y C C G+ C DV+EC S C G C + ++C C G G
Sbjct: 1305 EYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMF-GECENTKGSFICHCQLGYSVKKGT 1362
Query: 1156 LCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY--TGLRCEADINECRSGA 1213
+ D+C G C + +C+++ G F+C+C G+ G++C D++EC +G
Sbjct: 1363 TGCTDVDECEIG-----AHNCDMHASCLNIPGSFKCSCREGWIGNGIKC-IDLDECSNGT 1416
Query: 1214 CHAAHTRDCLQDPGGGFRCLCHAGFSGP--RCQTVLSPCESQPCQHGGQCRPSPGPGGGL 1271
+ C+ P G +RC C GF+G C V E+ GQC PG
Sbjct: 1417 HQCSINAQCVNTP-GSYRCACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPG----- 1470
Query: 1272 TFTCHCAQPFWGPRCERVARSCRELQ-------CPVGVPCQQTPRGPRCACPPGL----S 1320
+ C C F P + +RSC+++ C G C P C C G +
Sbjct: 1471 AYRCECEMGF-TPASD--SRSCQDIDECSFQNICVFGT-CNNLPGMFHCICDDGYELDRT 1526
Query: 1321 GPSCRSFP--GSPPGASNASCAAAPCLHGGSCRP 1352
G +C P N C P + +C P
Sbjct: 1527 GGNCTDIDECADPINCVNGLCVNTPGRYECNCPP 1560
Score = 373 bits (957), Expect = e-102
Identities = 459/1782 (25%), Positives = 657/1782 (36%), Gaps = 499/1782 (28%)
Query: 51 NGGRCTQLPSREAACLCPPGWVGERCQLEDP---------CHSGPCAGRG-VCQSSVVAG 100
+G RC + +C G V RC E P C G C G G + ++ V G
Sbjct: 354 DGSRCID----QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRG 409
Query: 101 TARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARC--------SVGPDGRFLCSCP----- 147
+ + C G P +P S P G GP G P
Sbjct: 410 SEEYRRLCMDGL--PMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGF 467
Query: 148 -PGYQGRSC---------------RSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTG 191
PG G +D C+ G C+ T S+RC+C GY
Sbjct: 468 SPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQ 527
Query: 192 PLCEN--PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDC--PGH 243
+ C +PC NG G +Y C C GF+ Q C +++D+C G
Sbjct: 528 DANGDCIDVDECTSNPCTNGDCVNTPG--SYYCKCHAGFQRTPTKQAC-IDIDECIQNGV 584
Query: 244 RCLNGGTCVDGVNTYNCQCPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
C N G CV+ ++ C C + G+ C D DEC N C N G C N G
Sbjct: 585 LCKN-GRCVNTDGSFQCICNAGFELTTDGKNCV-DHDEC-TTTNMCLN-GMCINEDGSFK 640
Query: 300 CVCVNGW----TGESCSQNIDDCAT-AVCFHGATCHDRVASFYCACP----MGKTGLLC- 349
C+C G+ G C+ ++D+C T +C +G C + SF C CP +G G +C
Sbjct: 641 CICKPGFVLAPNGRYCT-DVDECQTPGICMNG-HCINSEGSFRCDCPPGLAVGMDGRVCV 698
Query: 350 --HLDDACVS------------NPCHEDAICDTNPVNG----------------RAICTC 379
H+ C + C NP G +C+
Sbjct: 699 DTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSS 758
Query: 380 PPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNEC 435
G T +D++EC++ + C + G C N +GS+ C C GY +G C D++EC
Sbjct: 759 GVGIT--VDGRDINECALDPDICAN-GICENLRGSYRCNCNSGYEPDASGRNC-IDIDEC 814
Query: 436 LSGP--CRNQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNG 490
L C N C + G ++C C G+ T T DI+EC+S+PCVN G C++ +
Sbjct: 815 LVNRLLCDN-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGS 872
Query: 491 FSCTCPSGFSGS------------TCQLDVDE----------------CASTPCRNGAKC 522
F+C C G S TC L++ + CA+ G+ C
Sbjct: 873 FNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPC 932
Query: 523 VDQPDGYECRCAEG---FEGTLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGYT-- 575
+ + C G +G C+ +V++C P C +GRCV+ SF C C G T
Sbjct: 933 --ERCELDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLD 989
Query: 576 GT----------RCESQVDE----------------CRSQPCRHGGKCLDL----VDKYL 605
GT +C + DE C + G +C + +Y
Sbjct: 990 GTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYE 1049
Query: 606 CRCPSGT---------TGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFTGPL- 653
CP G TG +I++C + P CT+G CR+ I + C C GF +
Sbjct: 1050 TLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDME 1109
Query: 654 ---CNVEINECASSP--CG----------------------------------------- 667
C +I+EC SP CG
Sbjct: 1110 ERNC-TDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLL 1168
Query: 668 -EGGSCVDGENGFRCLCPPG-SLPPL---CLPPSH-PCAHEPCSHGICYDAPGGFRCVCE 721
GG+CV+ E F+C CP G L P C+ + + C +G C + G ++C C
Sbjct: 1169 CRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCN 1228
Query: 722 PGWSGPRCSQSLAR-DACESQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPCT 776
PG+ Q D C C++ + C+C G GR C + C
Sbjct: 1229 PGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECE 1288
Query: 777 PNP--CEHGGRCESAPGQLPVCSCPQGWQGPRCQQ---DVDECAGPAPCGPHGICTNLAG 831
NP C+ GG+C + PG+ C C G+ + DV+EC + G C N G
Sbjct: 1289 NNPDICD-GGQCTNIPGEYR-CLCYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKG 1346
Query: 832 SFSCTCHGGYT---GPSCDQDINDCD--PNPCLNGGSCQDGVGSFSCSCLPGFAGP--RC 884
SF C C GY+ G + D+++C+ + C SC + GSF CSC G+ G +C
Sbjct: 1347 SFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKC 1406
Query: 885 ARDVDECL--SNPCG-PGTCTDHVASFTCTCPPGY--GGFHCEQDLPDCSPS-SCFNGGT 938
D+DEC ++ C C + S+ C C G+ GF C D+ +C+ + + G
Sbjct: 1407 I-DLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC-SDVDECAENINLCENGQ 1464
Query: 939 CVDGVNSFSCLCRPGYTGA----HCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF-- 992
C++ ++ C C G+T A CQ + D C + G C+ F C C + +
Sbjct: 1465 CLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGTCNNLPGMFHCICDDGYEL 1523
Query: 993 --TGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGW----SGRLC-DIR------- 1036
TG C + + C N G CV T G Y C CPP + +G C D R
Sbjct: 1524 DRTGGNCTDIDECADPINCVN-GLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLK 1582
Query: 1037 -------SLPCREAAAQIGVRLEQLCQAGGQ--------CVDEDSS-HYCVCPEG----- 1075
SL C +GV C + G+ C +S+ +Y +CP G
Sbjct: 1583 FGPRGDGSLSCNTEIG-VGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRP 1641
Query: 1076 RTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGY---NGDNCEDDVDECASQP 1130
+ +++D C P CQ GG C G + CEC GY +D+DEC + P
Sbjct: 1642 NPITIILEDIDECQELPGLCQ-GGNCINTFGSFQCECPQGYYLSEDTRICEDIDECFAHP 1700
Query: 1131 CQHG-GSCIDLVARYLCSCPPGTL---------------------GVLCEINE------- 1161
G G+C + + Y C CPP + G CE NE
Sbjct: 1701 GVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCE-NELPFNVTK 1759
Query: 1162 --------------DDCGPGP---PLDSGPRC---------LHNGTCVDL---------- 1185
C P P D C +H G VD+
Sbjct: 1760 RMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNIPGFTFDIHTGKAVDIDECKEIPGIC 1819
Query: 1186 --------VGGFRCTCPPGYTG----LRCEADINECRSGACHAAHTRDCLQDPG------ 1227
+G FRC CP G++ L CE DI+EC +G DC+ PG
Sbjct: 1820 ANGVCINQIGSFRCECPTGFSYNDLLLVCE-DIDECSNGDNLCQRNADCINSPGSYRCEC 1878
Query: 1228 ----------------------------------GGFRCLCHAGFSGPRCQTV---LSPC 1250
G ++C+CH GF + QT+ + C
Sbjct: 1879 AAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDEC 1938
Query: 1251 ESQPCQHGGQCRPSPG-------PGGGLTFTCHC-----AQPFWGPRCE--RVARSCREL 1296
E PC + G C+ + G PG LT C F+G C R
Sbjct: 1939 ERHPCGN-GTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSF 1997
Query: 1297 QCPVGVPCQQTPRGPRC-------ACPPGLSGPSCRSFPGS-----PPGASNAS------ 1338
+C + TP G C A P S +C++ GS PPG S
Sbjct: 1998 KCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDI 2057
Query: 1339 --CAAAP--CLHGGSCRPAPLAPFFRCACAQGW----TGPRC 1372
C P CL GSC P F+C C G+ G RC
Sbjct: 2058 NECDEDPNICLF-GSCTNTPGG--FQCLCPPGFVLSDNGRRC 2096
Score = 365 bits (937), Expect = e-100
Identities = 412/1541 (26%), Positives = 583/1541 (37%), Gaps = 317/1541 (20%)
Query: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNC-EVNVDDCPGH 243
CP T P VP + C +G R + C C G C ++ C
Sbjct: 98 CPGWKTLPGGNQCIVPICRNSCGDGFCSRPNM-----CTCSSGQISSTCGSKSIQQC-SV 151
Query: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV 303
RC+NGGTC D +CQC + G +C + V E N C NGG C +G + C CV
Sbjct: 152 RCMNGGTCADD----HCQCQKGYIGTYCGQPVCE-----NGCQNGGRC---IGPNRCACV 199
Query: 304 NGWTGESCSQNIDDCATAVCF---HGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360
G+TG C + D T CF + C ++ C KT L C +PC
Sbjct: 200 YGFTGPQCER---DYRTGPCFTQVNNQMCQGQLTGIVCT----KT-LCCATIGRAWGHPC 251
Query: 361 HEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG 420
+C P R P GAC QDVDEC C+ G C+NT GSF C+C
Sbjct: 252 E---MCPAQPQPCRRGFI--PNIRTGAC-QDVDECQAIPGICQG-GNCINTVGSFECRCP 304
Query: 421 RGY----TGPRCETDVNEC--LSGPCRNQATCLDRIGQFTCICMAGFT----GTYCEVDI 470
G+ T +CE D++EC + G C C + +G + C+C G+ G+ C
Sbjct: 305 AGHKQSETTQKCE-DIDECSIIPGICET-GECSNTVGSYFCVCPRGYVTSTDGSRCIDQR 362
Query: 471 DECQSSPCVNGGVCKD---RVNGFSCTCPSGFSGS------TCQLDVDECASTPCRNGAK 521
S VNG ++ R+ C C G C + E C +G
Sbjct: 363 TGMCFSGLVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMDGLP 422
Query: 522 CVDQPDGYECRCA-EGFEGTLCDRNVDDCSPD-------PCHHGRC--VDGIASFSCACA 571
P R G G N + P P +G V G +
Sbjct: 423 MGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQG 482
Query: 572 PGYTGTRCESQ-VDECRSQP--CRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDCA 625
P TG +Q +D C+ C +G +C+ V Y C C G +C +++D+C
Sbjct: 483 PIITGLTILNQTIDICKHHANLCLNG-RCIPTVSSYRCECNMGYKQDANGDC-IDVDECT 540
Query: 626 SNPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINEC-ASSPCGEGGSCVDGENGFR 680
SNPCT G C + Y C C GF T C ++I+EC + + G CV+ + F+
Sbjct: 541 SNPCTNGDCVNTPGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRCVNTDGSFQ 599
Query: 681 CLCPPG----SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGW----SGPRCSQS 732
C+C G + C+ C +G+C + G F+C+C+PG+ +G C+
Sbjct: 600 CICNAGFELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTDV 659
Query: 733 LARDACESQPCRAGGTCSSDGMGFHCTCPP----GVQGRQC---ELLSPCTPNPCEHGGR 785
D C++ G C + F C CPP G+ GR C + S C + G
Sbjct: 660 ---DECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCY-GGIKKGVC 715
Query: 786 CESAPGQLP----VCSCPQGWQGPRCQ------------------------QDVDECAGP 817
PG + C+ P G CQ +D++ECA
Sbjct: 716 VRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALD 775
Query: 818 APCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCDPNPCL-NGGSCQDGVGSFS 872
+GIC NL GS+ C C+ GY +G +C DI++C N L + G C++ GS+S
Sbjct: 776 PDICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYS 834
Query: 873 CSCLPGF---AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPG----YGGFHCEQDL 925
C+C PG+ D++EC SNPC G C +++ SF C C PG G C L
Sbjct: 835 CTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSL 894
Query: 926 PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFR 985
GTC +N C GA + E C + G C
Sbjct: 895 K----------GTC--WLNIQDSRCEVNINGATLKSEC--CATLGAAWGSPCERCELDTA 940
Query: 986 C-TCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQT--GAYCLCPPG----WSGRLC-DI 1035
C L G C+ V+ C P C N GRCV + +C CP G +GR+C DI
Sbjct: 941 CPRGLARIKGVTCED-VNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLDI 998
Query: 1036 RSLPC------REAAAQI--GVRLEQLCQAGG--------QCVDEDSSHY-CVCPEGR-- 1076
R C E + R++ C A G +C + Y +CP G
Sbjct: 999 RMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGF 1058
Query: 1077 -------TGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGYNGD----NCED-- 1121
TG ++++ C A P C + G CR +G + C C G+ D NC D
Sbjct: 1059 ANRGDVLTGRPFYKDINECKAFPGMCTY-GKCRNTIGSFKCRCNSGFALDMEERNCTDID 1117
Query: 1122 ----------------------------------------DVDECASQPCQ-HGGSCIDL 1140
D+DEC P GG+C++
Sbjct: 1118 ECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNT 1177
Query: 1141 VARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL 1200
+ C CP LG + +DC NG CV+++G ++C+C PGY
Sbjct: 1178 EGSFQCDCP---LGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQAT 1234
Query: 1201 RCE---ADINEC--RSGACHAAHTRDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCE 1251
DI+EC +G C T + G + C C G++ G C + CE
Sbjct: 1235 PDRQGCTDIDECMIMNGGCDTQCT-----NSEGSYECSCSEGYALMPDGRSCADI-DECE 1288
Query: 1252 SQP--CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQ-----CPVGVPC 1304
+ P C GGQC PG + C C F + E C G C
Sbjct: 1289 NNPDICD-GGQCTNIPG-----EYRCLCYDGFMASMDMKTCIDVNECDLNSNICMFG-EC 1341
Query: 1305 QQTPRGPRCACPPGLS----GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFR 1360
+ T C C G S C GA N A+ CL+ + F+
Sbjct: 1342 ENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHAS-CLN--------IPGSFK 1392
Query: 1361 CACAQGWTGPRCEAPAAAPEVSEEPRCP-RAACQAKRGDQRCDRECNSPGCGWDGGDCS- 1418
C+C +GW G + + +C A C G RC S G DG CS
Sbjct: 1393 CSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC---ACSEGFTGDGFTCSD 1449
Query: 1419 -LSVGDPWRQCEALQCWRLFNNSRCD------PACSSPA------CLYDNFDCHAGGRER 1465
+ CE QC + RC+ PA S + C + N C G
Sbjct: 1450 VDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNI-CVFG---- 1504
Query: 1466 TCN---PVYEKYCADHFADGRCDQGC-NTEECGWDGLDCAS 1502
TCN ++ C D + R C + +EC D ++C +
Sbjct: 1505 TCNNLPGMFHCICDDGYELDRTGGNCTDIDECA-DPINCVN 1544
Score = 166 bits (420), Expect = 2e-40
Identities = 140/491 (28%), Positives = 206/491 (41%), Gaps = 103/491 (20%)
Query: 65 CLCPPGWV----GERCQLEDPCHSGPCAGRGVCQSS-VVAGTARFSCRCPRGFR----GP 115
C+CPPG GE C E+ C + P G+C++ V + C C GF+ G
Sbjct: 2321 CICPPGMARRPDGEGCVDENECRTKP----GICENGRCVNIIGSYRCECNEGFQSSSSGT 2376
Query: 116 DCS-----------LPDPCL-----------SSPCAHGAR--------CSVGPDGRFLCS 145
+C L C S C G R C + ++
Sbjct: 2377 ECLDNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKI 2436
Query: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP---CA 202
CP G + D+DEC+V G C+NT GSFRC C GYT + + C+
Sbjct: 2437 CPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECS 2496
Query: 203 PSPCRNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258
SP C+ + + +Y C+C G+ +G+ C+ ++D+C + CV+ + +
Sbjct: 2497 QSPKPCNYICKNT-EGSYQCSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGF 2554
Query: 259 NCQCPPEWTGQFCTEDVD--ECQLQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCS 312
C+CPP +T Q T +D EC QP+ C G C NT G SC C G+ TG +C
Sbjct: 2555 TCKCPPGFT-QHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC- 2612
Query: 313 QNIDDC-ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACV-SNPCHEDAICDTN 369
+++D+C C HG C + + + C CP G + H + CV N C C +
Sbjct: 2613 EDVDECDGNHRCQHG--CQNILGGYRCGCPQ---GYIQHYQWNQCVDENECSNPNACGSA 2667
Query: 370 P---VNGRAICTCPPGFT----GGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRG 422
G C CP GF+ AC DV+ECS NPC + C NT+G +LC C G
Sbjct: 2668 SCYNTLGSYKCACPSGFSFDQFSSAC-HDVNECSSSKNPCNY--GCSNTEGGYLCGCPPG 2724
Query: 423 YTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFT-GTYCEVDIDECQSSPCVNG 481
Y R+GQ C+ GF G Y +D + + +
Sbjct: 2725 YY------------------------RVGQGHCVSGMGFNKGQYLSLDTEVDEENALSPE 2760
Query: 482 GVCKDRVNGFS 492
+ ++NG+S
Sbjct: 2761 ACYECKINGYS 2771
Score = 132 bits (333), Expect = 3e-30
Identities = 203/780 (26%), Positives = 266/780 (34%), Gaps = 197/780 (25%)
Query: 753 GMGFHCTCPPGVQ----GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC- 807
G FH C PG + G QC + P N C G C S P +C+C G C
Sbjct: 90 GSRFHSYCCPGWKTLPGGNQC--IVPICRNSCGDGF-C-SRPN---MCTCSSGQISSTCG 142
Query: 808 QQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDG 867
+ + +C+ C G C + C C GY G C Q + C+ N C NGG C
Sbjct: 143 SKSIQQCS--VRCMNGGTCAD----DHCQCQKGYIGTYCGQPV--CE-NGCQNGGRC--- 190
Query: 868 VGSFSCSCLPGFAGPRCARDVDECLSNPC----GPGTCTDHVASFTCT---CPPGYG--- 917
+G C+C+ GF GP+C RD + PC C + CT C G
Sbjct: 191 IGPNRCACVYGFTGPQCERDYR---TGPCFTQVNNQMCQGQLTGIVCTKTLCCATIGRAW 247
Query: 918 GFHCE----------------------QDLPDCS--PSSCFNGGTCVDGVNSFSCLCRPG 953
G CE QD+ +C P C GG C++ V SF C C G
Sbjct: 248 GHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGIC-QGGNCINTVGSFECRCPAG 306
Query: 954 Y----TGAHCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESF-TGPQCQTLVDWCSRQ 1007
+ T C+ + D C P + G CS + C C + T +D +
Sbjct: 307 HKQSETTQKCE-DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGM 365
Query: 1008 PCQNG---GRCVQ------TGAYCLCPPGWSGRLCDIRSLPCREAAAQIG-VRLEQLCQA 1057
C +G GRC Q T C C P GR I ++P EA G +LC
Sbjct: 366 -CFSGLVNGRCAQELPGRMTKMQCCCEP---GRCWGIGTIP--EACPVRGSEEYRRLCMD 419
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY-MGGYMCECLPGYNG 1116
G P G G GY GG +PG NG
Sbjct: 420 G-------------LPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNG 466
Query: 1117 -----------------------------DNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
D C+ + C + G CI V+ Y C
Sbjct: 467 FSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLN------GRCIPTVSSYRCE 520
Query: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCE 1203
C +G + N DC S P NG CV+ G + C C G+ T C
Sbjct: 521 C---NMGYKQDAN-GDCIDVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQAC- 573
Query: 1204 ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGG 1259
DI+EC + R C+ + G F+C+C+AGF G C C + G
Sbjct: 574 IDIDECIQNGVLCKNGR-CV-NTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNG 630
Query: 1260 QCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCP---VGVPCQQTPRGPRCACP 1316
C G +F C C F R E Q P + C + RC CP
Sbjct: 631 MCINEDG-----SFKCICKPGFVLAPNGRYCTDVDECQTPGICMNGHCINSEGSFRCDCP 685
Query: 1317 PGLS-----------------------GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPA 1353
PGL+ G R FPG+ S CA G C+P
Sbjct: 686 PGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVT-KSECCCANPDYGFGEPCQPC 744
Query: 1354 PL--APFFRCACAQG----WTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNS 1407
P + F C+ G G A P++ C C+ RG RC+ CNS
Sbjct: 745 PAKNSAEFHGLCSSGVGITVDGRDINECALDPDI-----CANGICENLRGSYRCN--CNS 797
Score = 86.7 bits (213), Expect = 2e-16
Identities = 111/414 (26%), Positives = 151/414 (36%), Gaps = 85/414 (20%)
Query: 976 VCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
VC + + C ++ G Q +V C R C +G C + C C G C
Sbjct: 88 VCGSRFHSYCCPGWKTLPGGN-QCIVPIC-RNSCGDGF-CSRPNM-CTCSSGQISSTCGS 143
Query: 1036 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQH 1095
+S+ Q VR C GG C D+ +C C +G G++C Q P CQ+
Sbjct: 144 KSIQ------QCSVR----CMNGGTCADD----HCQCQKGYIGTYCGQ---PVCENGCQN 186
Query: 1096 GGTCRGYMGGYMCECLPGYNGDNCEDDV------DECASQPCQHGGSCIDLVARYLCS-- 1147
GG C +G C C+ G+ G CE D + +Q CQ + I C+
Sbjct: 187 GGRC---IGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCATI 243
Query: 1148 ----------CP----PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC 1193
CP P G + I C + P G C++ VG F C C
Sbjct: 244 GRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRC 303
Query: 1194 PPGY----TGLRCEADINECR--SGACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRC 1243
P G+ T +CE DI+EC G C T +C G F C+C G+ G RC
Sbjct: 304 PAGHKQSETTQKCE-DIDECSIIPGIC---ETGECSNTVGSYF-CVCPRGYVTSTDGSRC 358
Query: 1244 QTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQC-PVGV 1302
Q G C G CAQ G R ++ C +C +G
Sbjct: 359 ID----------QRTGMCFSGLVNG-------RCAQELPG-RMTKMQCCCEPGRCWGIGT 400
Query: 1303 PCQQTP-RGP---RCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP 1352
+ P RG R C GL GS PG + + AP +G P
Sbjct: 401 IPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGGTGGN-GFAPSGNGNGYGP 453
Score = 38.5 bits (88), Expect = 0.078
Identities = 41/158 (25%), Positives = 54/158 (34%), Gaps = 33/158 (20%)
Query: 1220 RDCLQDP---GGGFRCLCHAGFSG-PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC 1275
+D L+ P G F C G+ P + P C G RP+ C
Sbjct: 80 QDVLRGPNVCGSRFHSYCCPGWKTLPGGNQCIVPICRNSCGDGFCSRPN---------MC 130
Query: 1276 HCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGAS 1335
C+ C + ++C G C C C G G C P
Sbjct: 131 TCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQKGYIGTYC-----GQPVCE 181
Query: 1336 NASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
N C +GG C + P RCAC G+TGP+CE
Sbjct: 182 NG------CQNGGRC----IGPN-RCACVYGFTGPQCE 208
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 453 bits (1165), Expect = e-126
Identities = 248/727 (34%), Positives = 329/727 (45%), Gaps = 73/727 (10%)
Query: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
C G+ G +C HG C+V + C C G+QGR C DEC
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGG-CTVPGE----CRCSYGWQGRFC----DECVPYPG 281
Query: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPS-PCRNGGTCRQSGDLTYDCACLP 226
C HG +C+ ++C C + G LC+ C PC NGGTC + Y C C
Sbjct: 282 CVHG-SCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPD 337
Query: 227 GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACH 286
G+ G+NCE C + C NGG+C + + + C CP W+G C D+DEC P C
Sbjct: 338 GYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP--CA 395
Query: 287 NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTG 346
GGTC + + G C+C W G +C +++DC C HG TC D V + C CP G G
Sbjct: 396 AGGTCVDQVDGFECICPEQWVGATCQLDVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGG 454
Query: 347 LLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHL 405
C L+ D C S+PCH +C+ + C CP GF+G C+ DVD C +PC +
Sbjct: 455 RHCELERDECASSPCHSGGLCE--DLADGFHCHCPQGFSGPLCEVDVDLCE--PSPCRNG 510
Query: 406 GRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCR-----------------------N 442
RC N +G + C C + G C C G CR
Sbjct: 511 ARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGP 570
Query: 443 QATCLDRI-GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSG 501
C+ + G F+CIC +GFTGTYC +ID+C PC NGG C D V+ F C CPSG+ G
Sbjct: 571 HGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEG 630
Query: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH-GRCV 560
C + ++C PC + +C D + + C C +G++G C C C + G C
Sbjct: 631 ELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCY 690
Query: 561 DGIASFSCACAPGYTGTRCE-SQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEV 619
D +F CAC PG+ G+ C ++ C PC +GG C+ + C C G G C
Sbjct: 691 DSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTH 750
Query: 620 NIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENG 678
N +DC PC G+C DG+N + C C PGF GP C + I+EC SSPC G +CVD NG
Sbjct: 751 NTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEING 810
Query: 679 FRCLCPPGSLPP----------LCLPPSHPCAH-----EPCSHGICYDAPGGFRCVCEPG 723
+RC CPPG P C P H E C+ C D R C
Sbjct: 811 YRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG----RRDCSKV 866
Query: 724 WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPP----GVQGRQCELLSPCTPNP 779
W G + + S C G C G C PP G G + +PC P
Sbjct: 867 WCGWKPCLLAGQPEALSAQCPLGQRCLEKAPG-QCLRPPCEAWGECGAEEPPSTPCLPRS 925
Query: 780 CEHGGRC 786
C
Sbjct: 926 GHLDNNC 932
Score = 449 bits (1156), Expect = e-125
Identities = 251/676 (37%), Positives = 315/676 (46%), Gaps = 63/676 (9%)
Query: 377 CTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
C C G+ G CD EC + C H G CV + C C + G C+ D+N C
Sbjct: 262 CRCSYGWQGRFCD----EC-VPYPGCVH-GSCVEP---WQCNCETNWGGLLCDKDLNYCG 312
Query: 437 SG-PCRNQATCLD-RIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCT 494
S PC N TC++ Q+ C C G++G CE C S+PC NGG C + +GF C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECH 372
Query: 495 CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC 554
CPSG+SG TC LD+DECAS PC G CVDQ DG+EC C E + G C +V+DC
Sbjct: 373 CPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQ 432
Query: 555 HHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTG 614
H G C D + + C C G+ G CE + DEC S PC GG C DL D + C CP G +G
Sbjct: 433 HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSG 492
Query: 615 VNCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGFTGPLCNVEINEC------------ 661
CEV++D C +PC G C + Y C C F G C+V C
Sbjct: 493 PLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 552
Query: 662 -----------ASSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPPSHPCAHEPCSH-GI 708
AS CG G CV G F C+C G C C +PC + G
Sbjct: 553 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 612
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ 768
C D FRC C GW G C + + C PC + G C F+C C G +G+
Sbjct: 613 CIDEVDAFRCFCPSGWEGELCDTN--PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKT 670
Query: 769 CELLS-PCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT 827
C C C +GG C + G C+CP GW+G C + P PC G C
Sbjct: 671 CHSREFQCDAYTCSNGGTCYDS-GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCV 729
Query: 828 NLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
SFSC C G+ G +C + NDC+P PC NGG C DGV F C C PGFAGP C +
Sbjct: 730 GSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRIN 789
Query: 888 VDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSF 946
+DEC S+PC G TC D + + C+CPPG G C++ + SC++ GT +S+
Sbjct: 790 IDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIG--FGRSCWSRGTPFPHGSSW 847
Query: 947 -----SCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSA--AHPGFRCTCLESFTGPQCQT 999
SC C G C +PCL G A A CLE G
Sbjct: 848 VEDCNSCRCLDGRRDC----SKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQ---- 899
Query: 1000 LVDWCSRQPCQNGGRC 1015
C R PC+ G C
Sbjct: 900 ----CLRPPCEAWGEC 911
Score = 403 bits (1036), Expect = e-112
Identities = 232/718 (32%), Positives = 311/718 (43%), Gaps = 133/718 (18%)
Query: 797 SCPQGWQGPRCQQDV-----------------------------DECAGPAP-------- 819
+C GW G C++ V DEC P P
Sbjct: 230 ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECV-PYPGCVHGSCV 288
Query: 820 ----------------------CGPHGICTN-------LAGSFSCTCHGGYTGPSCDQDI 850
CG H CTN + CTC GY+G +C++
Sbjct: 289 EPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAE 348
Query: 851 NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGP-GTCTDHVASFT 909
+ C NPC NGGSC + F C C G++GP CA D+DEC SNPC GTC D V F
Sbjct: 349 HACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFE 408
Query: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
C CP + G C+ D+ DC C +GGTC D VN + C+C G+ G HC+ E D C S
Sbjct: 409 CICPEQWVGATCQLDVNDCR-GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASS 467
Query: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCPPG 1027
PC GG+C GF C C + F+GP C+ VD C PC+NG RC ++ YC CP
Sbjct: 468 PCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDD 527
Query: 1028 WSGRLCDIRSLPCREAAAQI-------------GVRLEQLCQAGGQCVDEDSSHY-CVCP 1073
+ G+ C + PC A ++ G +C G+CV + ++ C+C
Sbjct: 528 FGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 587
Query: 1074 EGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQH 1133
G TG++C + +D CL QPC++GGTC + + C C G+ G+ C+ + ++C PC
Sbjct: 588 SGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHS 647
Query: 1134 GGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC 1193
G C DLV + C+C G G C E C C + GTC D FRC C
Sbjct: 648 RGRCYDLVNDFYCACDDGWKGKTCHSREFQC-------DAYTCSNGGTCYDSGDTFRCAC 700
Query: 1194 PPGYTGLRCE-ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
PPG+ G C A + C C T C+ G F C+C G+ G C + C
Sbjct: 701 PPGWKGSTCAVAKNSSCLPNPCVNGGT--CV-GSGASFSCICRDGWEGRTCTHNTNDCNP 757
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
PC +GG C G F C CA F GP C C+ C G C G R
Sbjct: 758 LPCYNGGIC-----VDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYR 812
Query: 1313 CACPPGLSGPSCRSFPG-----------SPPGAS-NASCAAAPCLHGGSCRPAPLAPFFR 1360
C+CPPG +GP C+ G P G+S C + CL G R
Sbjct: 813 CSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDG------------R 860
Query: 1361 CACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGC-GWDGGDC 1417
C++ W G + A PE + +CP +R ++ +C P C W G+C
Sbjct: 861 RDCSKVWCGWKPCLLAGQPE-ALSAQCP----LGQRCLEKAPGQCLRPPCEAW--GEC 911
Score = 391 bits (1004), Expect = e-108
Identities = 224/631 (35%), Positives = 294/631 (46%), Gaps = 64/631 (10%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-LEDPCHSGPCAGRGVCQSSVVAGT 101
C PC NGG C + C CP G+ G C+ E C S PCA G C V +G
Sbjct: 311 CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCH-EVPSG- 368
Query: 102 ARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
F C CP G+ GP C+L D C S+PCA G C DG F C CP + G +C+ DV+
Sbjct: 369 --FECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDG-FECICPEQWVGATCQLDVN 425
Query: 161 ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTY 220
+CR C+HGGTC + ++C CP G+ G CE CA SPC +GG C D +
Sbjct: 426 DCR--GQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD-GF 482
Query: 221 DCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDEC-- 278
C C GF G CEV+VD C C NG C + Y C CP ++ G+ C+ + C
Sbjct: 483 HCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPG 542
Query: 279 -------------------QLQPNACHNGGTCFNTLGGH-SCVCVNGWTGESCSQNIDDC 318
C G C + GG+ SC+C +G+TG C +NIDDC
Sbjct: 543 GACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDC 602
Query: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAIC 377
C +G TC D V +F C CP G G LC + + C+ +PCH C + VN C
Sbjct: 603 LGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRC-YDLVND-FYC 660
Query: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN-ECL 436
C G+ G C +C A C + G C ++ +F C C G+ G C N CL
Sbjct: 661 ACDDGWKGKTCHSREFQCD--AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCL 718
Query: 437 SGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCP 496
PC N TC+ F+CIC G+ G C + ++C PC NGG+C D VN F C C
Sbjct: 719 PNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECA 778
Query: 497 SGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVD---DC---- 549
GF+G C++++DEC S+PC GA CVD+ +GY C C G G C + C
Sbjct: 779 PGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRG 838
Query: 550 SPDP--------CHHGRCVDGIASFS---CACAPGYTGTRCESQVDECRSQPCRHGGKCL 598
+P P C+ RC+DG S C P + E S C G +CL
Sbjct: 839 TPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQ-----PEALSAQCPLGQRCL 893
Query: 599 DLVDKYLCRCPSGTTGVNCEVNIDDCASNPC 629
+ R P G E ++ S PC
Sbjct: 894 EKAPGQCLRPPCEAWG---ECGAEEPPSTPC 921
Score = 338 bits (868), Expect = 3e-92
Identities = 229/745 (30%), Positives = 309/745 (41%), Gaps = 96/745 (12%)
Query: 806 RCQQDVDECAGPAPCGPHGICTNLAGSFSC------TCHGGYTGPSCDQDINDCDPNPCL 859
RC ++ C P + G ++C C G+ G C + + N L
Sbjct: 197 RCDENYYSATCNKFCRPRN---DFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCN-LL 252
Query: 860 NGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVASFTCTCPPGYGG 918
+GG G C C G+ G C DEC+ P C G+C V + C C +GG
Sbjct: 253 HGGCTVPG----ECRCSYGWQGRFC----DECVPYPGCVHGSC---VEPWQCNCETNWGG 301
Query: 919 FHCEQDLPDC-SPSSCFNGGTCVDGV-NSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV 976
C++DL C S C NGGTC++ + + C C GY+G +C+ C S PC +GG
Sbjct: 302 LLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGS 361
Query: 977 CSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPGWSGRLCD 1034
C GF C C ++GP C +D C+ PC GG CV G C+CP W G C
Sbjct: 362 CHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQ 421
Query: 1035 IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQ 1094
+ CR CQ GG C D + + CVCP G G HCE E D C + PC
Sbjct: 422 LDVNDCRGQ-----------CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCH 470
Query: 1095 HGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLG 1154
GG C G+ C C G++G CE DVD C PC++G C +L Y C+CP G
Sbjct: 471 SGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGG 530
Query: 1155 VLCEINEDDC---------------GPG-PPLDSGPRCLHNGTCVDLVGG-FRCTCPPGY 1197
C + + C GPG P + C +G CV GG F C C G+
Sbjct: 531 KNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGF 590
Query: 1198 TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
TG C +I++C C T C+ D FRC C +G+ G C T + C PC
Sbjct: 591 TGTYCHENIDDCLGQPCRNGGT--CI-DEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHS 647
Query: 1258 GGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPP 1317
G+C F C C + G C C C G C + RCACPP
Sbjct: 648 RGRCYDLVN-----DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 702
Query: 1318 GLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA 1377
G G +C A N+SC PC++GG+C + + F C C GW G C
Sbjct: 703 GWKGSTCAV-------AKNSSCLPNPCVNGGTCVGSGAS--FSCICRDGWEGRTC--THN 751
Query: 1378 APEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA------L 1431
+ + P C RC EC G+ G DC +++ +C++
Sbjct: 752 TNDCNPLPCYNGGICVDGVNWFRC--EC---APGFAGPDCRINID----ECQSSPCAYGA 802
Query: 1432 QCWRLFNNSRCD--PACSSPAC---LYDNFDCHAGGRERTCNPVYEKYC-ADHFADGRCD 1485
C N RC P + P C + C + G + + C + DGR D
Sbjct: 803 TCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRD 862
Query: 1486 QGCNTEECGWDGLDCASEVPALLAR 1510
C+ CGW A + AL A+
Sbjct: 863 --CSKVWCGWKPCLLAGQPEALSAQ 885
Score = 207 bits (527), Expect = 1e-52
Identities = 110/287 (38%), Positives = 143/287 (49%), Gaps = 18/287 (6%)
Query: 34 AGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGV 92
AGPG P C GRC P +C+C G+ G C D C PC G
Sbjct: 555 AGPGM--PGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 612
Query: 93 CQSSVVAGTARFSCRCPRGFRGPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ 151
C V A F C CP G+ G C P+ CL PC RC F C+C G++
Sbjct: 613 CIDEVDA----FRCFCPSGWEGELCDTNPNDCLPDPCHSRGRC-YDLVNDFYCACDDGWK 667
Query: 152 GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRN 208
G++C S +C C +GGTC ++ +FRC CP G+ G C +N + C P+PC N
Sbjct: 668 GKTCHSREFQCD-AYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS--CLPNPCVN 724
Query: 209 GGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG 268
GGTC SG ++ C C G+EG+ C N +DC C NGG CVDGVN + C+C P + G
Sbjct: 725 GGTCVGSG-ASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAG 783
Query: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI 315
C ++DECQ P C G TC + + G+ C C G G C + I
Sbjct: 784 PDCRINIDECQSSP--CAYGATCVDEINGYRCSCPPGRAGPRCQEVI 828
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 446 bits (1148), Expect = e-125
Identities = 493/1765 (27%), Positives = 665/1765 (37%), Gaps = 424/1765 (24%)
Query: 55 CTQLPSREAACLCPPG-------WVGERCQLED----PCHSGPCAGRGVCQSSVVAGTAR 103
C S E A LCP G ++ R +D G C G C+++V
Sbjct: 954 CPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCT-HGTCRNTV----GS 1008
Query: 104 FSCRCPRGF----RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQG-----RS 154
F C C GF + +C+ D C SP G V G F C C PGY+ ++
Sbjct: 1009 FHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKN 1068
Query: 155 CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAPSP--CRN 208
C DVDEC GGTC NT GS++CQCP G+ G CE+ C+ S C +
Sbjct: 1069 CM-DVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACED-IDECSLSDGLCPH 1126
Query: 209 GGTCRQSGDLTYDCACLPGFEG----QNCEVNVDDCPGHRCLNGGTCVDGVNT---YNCQ 261
G G + C+C GF+ Q C V++++C R NGG V +NT Y C
Sbjct: 1127 GQCVNVIG--AFQCSCHAGFQSTPDRQGC-VDINEC---RVQNGGCDVHCINTEGSYRCS 1180
Query: 262 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQ---N 314
C ++ G+ C DVDEC+ P C G C N GGH C+C +G+ + +
Sbjct: 1181 CGQGYSLMPDGRACA-DVDECEENPRVCDQGH-CTNMPGGHRCLCYDGFMATPDMRTCVD 1238
Query: 315 IDDCATA--VCFHGATCHDRVASFYCACPMG----KTGLLCHLDDACV--SNPCHEDAIC 366
+D+C +C HG C + SF C C +G K C D C + C A C
Sbjct: 1239 VDECDLNPHICLHG-DCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASC 1297
Query: 367 DTNPVNGRAICTCPPGFTGGACD-QDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTG 425
P G C C PG+ G + D+DEC + C G C+N GS+ C C +G+ G
Sbjct: 1298 LNIP--GSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Query: 426 P-----------------------------RCET--------------DVNECLSGPCRN 442
RCE DV+EC G
Sbjct: 1356 DGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCA 1415
Query: 443 QATCLDRIGQFTCICMAGFT----GTYCEVDIDECQSSP-CVNGGVCKDRVNGFSCTCPS 497
+C + G F CIC G+ G C DI+EC C+NG VC + + C+CP
Sbjct: 1416 FGSCENLPGMFRCICNGGYELDRGGGNC-TDINECADPVNCING-VCINTPGSYLCSCPQ 1473
Query: 498 GF--------------------------SGSTCQLDVDE-------CASTPCRNGAKCVD 524
F SG +C ++ C S G C
Sbjct: 1474 DFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCEL 1533
Query: 525 QPDG----YECRC--AEGFEG---TLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPG 573
P Y C EGF+ T+ ++D+C P C G CV+ SF C C PG
Sbjct: 1534 CPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPG 1593
Query: 574 Y---TGTRCESQVDECRSQPCRHG-GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC 629
Y TR +DEC + G G C + + Y C CP+ VN N D + C
Sbjct: 1594 YHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVC 1653
Query: 630 TFGVCRDGINRYDCVCQPGFTGPL------CNVEINECASSPCGEGGSCVDGENGFRCLC 683
Y+ CQ + C+ I + + PC + + + ++ LC
Sbjct: 1654 --------FRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPD--YQILC 1703
Query: 684 PPGSLPPLCLPPSHP--------CAHEP--CSHGICYDAPGGFRCVCEPGWSGPRCSQSL 733
G+ P L H C P C++GIC + G FRC C G++ +
Sbjct: 1704 --GNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLAC 1761
Query: 734 AR-DACESQ--PCRAGGTCSSDGMGFHCTCPPGVQ---GRQCELLSPCT--PNPCEHGGR 785
D C S+ PC+ C + + C C G + G C + C PN C HG
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGD- 1820
Query: 786 CESAPGQLPVCSCPQGWQGPRCQ---QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT 842
C G +C C +G+Q Q D+DEC PCG +G C N+ GS++C C G+
Sbjct: 1821 CMDTEGSY-MCLCHRGFQASADQTLCMDIDEC-DRQPCG-NGTCKNIIGSYNCLCFPGFV 1877
Query: 843 GPSCDQDINDCDPNPCLNG-----GSCQDGVGSFSCSCLPGFA----GPRCARDVDECLS 893
+ + D D D L G G C + GSF C C GF G C D +ECLS
Sbjct: 1878 -VTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCV-DTNECLS 1935
Query: 894 --NPCGPGTCTDHVASFTCTCPPGYG--GFHCEQDLPDCS--PSSCFNGGTCVDGVNSFS 947
C PGTC + SF C CPPG+ HC D+ +CS P+ C G TC + SF
Sbjct: 1936 LAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCI-DIDECSEEPNLCLFG-TCTNSPGSFQ 1993
Query: 948 CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ 1007
CLC PG+ + H C C +C+ ++F + + CS++
Sbjct: 1994 CLCPPGFVLSDNGHR---CFDT---RQSFCFTRFEAGKCSVPKAFNTTKTRCC---CSKR 2044
Query: 1008 PCQNGGR----CVQTGAYC---LCP------PGWSGRLCDIRSLPCREAAAQIGVRLEQL 1054
P + G C Q G+ LCP PG D+ E A GV
Sbjct: 2045 PGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVN-----ECAENPGV----- 2094
Query: 1055 CQAGGQCVDEDSSHYCVCPEGR----TGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCEC 1110
C G CV+ D S C CP G TG +C + + PC G TC +GG+ C C
Sbjct: 2095 C-TNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQG-TCTNVIGGFECAC 2152
Query: 1111 LPGYNGD---NCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG-TL---GVLCEINEDD 1163
G+ CED +DEC+ P C + YLC+CP G TL G +C + D+
Sbjct: 2153 ADGFEPGLMMTCED-IDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDE 2210
Query: 1164 CGPG---------------------------PPLDSGPRCLH------------NGTCVD 1184
C G P SG C NG CV+
Sbjct: 2211 CADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDNECHAQPDLCVNGRCVN 2270
Query: 1185 LVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGG------FRCLCHAGF 1238
G FRC C G+ + ++ R G C A + + C C G
Sbjct: 2271 TAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGR 2330
Query: 1239 S-GPRCQTVLSPCES---QPCQHG----------------------GQCRPSPGPGGGLT 1272
GPRC+ P S + C HG G+C S G +
Sbjct: 2331 GWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLG-----S 2385
Query: 1273 FTCHCAQPFWGPRCERVA----RSCRELQCPVGVPCQQTPRGPRCACPPGL----SGPSC 1324
F CHC Q + P C ++ P C+ T C+CP G G +C
Sbjct: 2386 FRCHC-QAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTC 2444
Query: 1325 RSFP----------------------GSPPGAS--------NASCAA--APCLHGGSCRP 1352
+ PPG + N C+A PC G C
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHN 2504
Query: 1353 APLAPFFRCACAQGWT----GPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCD-RECNS 1407
P + FRC C QG+T G CE E RC + CQ + G RC + +
Sbjct: 2505 TPGS--FRCECHQGFTLVSSGHGCE---DVNECDGPHRC-QHGCQNQLGGYRCSCPQGFT 2558
Query: 1408 PGCGW----DGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR 1463
W D +C+LS C + C RC C S +FD GG
Sbjct: 2559 QHSQWAQCVDENECALSP----PTCGSASCRNTLGGFRC--VCPSGF----DFDQALGG- 2607
Query: 1464 ERTCNPVYEKYCADHFADGRCDQGC 1488
C V E CA G C C
Sbjct: 2608 ---CQEVDE--CAGR--RGPCSYSC 2625
Score = 444 bits (1143), Expect = e-124
Identities = 442/1508 (29%), Positives = 593/1508 (39%), Gaps = 300/1508 (19%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVG----ERCQLEDPCHSGP--CAGRGVCQSS 96
C + + G CT +P CLC G++ C D C P C G C+++
Sbjct: 1200 CEENPRVCDQGHCTNMPGGHR-CLCYDGFMATPDMRTCVDVDECDLNPHICL-HGDCENT 1257
Query: 97 VVAGTARFSCRCPRGFR----GPDCSLPDPCL--SSPCAHGARCSVGPDGRFLCSCPPGY 150
F C C G+ CS D C C A C P G F C C PG+
Sbjct: 1258 ----KGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIP-GSFSCRCLPGW 1312
Query: 151 QGRSCRS-DVDECRVGEP-CRHGGTCLNTPGSFRCQCPAGYTGP--LCENPAVPCAPSP- 205
G D+DEC E C G CLN PGS+RC C G+ G CE+ CA +
Sbjct: 1313 VGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRD-ECAENVD 1371
Query: 206 -CRNGGTCRQSGDLTYDCACLPGF---EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 261
C NG G Y C C GF E +VD+C G+C + + C
Sbjct: 1372 LCDNGQCLNAPGG--YRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCI 1429
Query: 262 CPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDD 317
C + G CT D++EC P C NG C NT G + C C + D
Sbjct: 1430 CNGGYELDRGGGNCT-DINECA-DPVNCING-VCINTPGSYLCSCPQDFELNPSGVGCVD 1486
Query: 318 CATAVCF--------HGATCHDRV------ASFYCA-----------CPMGKTG---LLC 349
CF G +C + AS C+ CPM T LC
Sbjct: 1487 TRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLC 1546
Query: 350 HLDDACVSN----------PCHE-DAIC---DTNPVNGRAICTCPPGF---TGGACDQDV 392
+ N C E +C D G C CPPG+ +D+
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDI 1606
Query: 393 DECSIGANPCEHLGRCVNTQGSFLCQCGRGYT----GPRCE-------------TDVNEC 435
DECS + C G C NT G++ C C Y G C T NE
Sbjct: 1607 DECSTHSGICGP-GTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNEL 1665
Query: 436 LSGPCRNQATCLDRIGQ----------------FTCICMAGFTGTYCEV------DIDEC 473
R C IGQ + +C G ++ DIDEC
Sbjct: 1666 AFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDEC 1725
Query: 474 QSSP--CVNGGVCKDRVNGFSCTCPSGFSGSTCQL---DVDECAS--TPCRNGAKCVDQP 526
P C NG +C +++ F C CP+GF+ ++ L DVDEC S +PC+ A C++ P
Sbjct: 1726 GEIPAICANG-ICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 527 DGYECRCAEGFE----GTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCES- 581
Y C+C G++ G RN P+ C HG C+D S+ C C G+ + ++
Sbjct: 1785 GSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTL 1844
Query: 582 --QVDECRSQPCRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDCAS---NPCTFGV 633
+DEC QPC +G C +++ Y C C G T +C V+ D+C + C FG
Sbjct: 1845 CMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVCRFGH 1902
Query: 634 CRDGINRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDG-----ENGFRCLCP 684
C + + C+CQ GF G C V+ NEC S G+C+ G E FRC+CP
Sbjct: 1903 CLNTAGSFHCLCQDGFELTADGKNC-VDTNECLSL----AGTCLPGTCQNLEGSFRCICP 1957
Query: 685 PGSLPPL--CLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGW----SGPRC------- 729
PG C+ C+ EP C G C ++PG F+C+C PG+ +G RC
Sbjct: 1958 PGFQVQSDHCIDIDE-CSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSF 2016
Query: 730 ----------------SQSLARDACESQPCRAGGT----CSSDGMG-FHCTCP------P 762
+ + R C +P G C +G F CP P
Sbjct: 2017 CFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP 2076
Query: 763 GVQGRQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECAG 816
G + E ++ C NP C +G C + G C CP G+ G C D DEC+
Sbjct: 2077 GPDDSR-EDVNECAENPGVCTNGV-CVNTDGSFR-CECPFGYSLDFTGINCV-DTDECSV 2132
Query: 817 PAPCGPHGICTNLAGSFSCTCHGGYTGP---SCDQDINDCDPNPCLNGGSCQDGVGSFSC 873
PCG G CTN+ G F C C G+ +C+ DI++C NP L C + GS+ C
Sbjct: 2133 GHPCG-QGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTEGSYLC 2190
Query: 874 SCLPGFA----GPRCARDVDECLSNP----CGPGTCTDHVASFTCTCPPGY-----GGFH 920
+C G+ G C RDVDEC C + + +F C CPPG G
Sbjct: 2191 TCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEG 2249
Query: 921 CEQDLPDC--SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCS 978
C D +C P C NG CV+ SF C C G+ + E PC +
Sbjct: 2250 CTDD-NECHAQPDLCVNG-RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVL-- 2305
Query: 979 AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ-----TGAYC-LCPPGWSGRL 1032
+ C + + T + C G RC T AY LCP G SG
Sbjct: 2306 ------QTMCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHG-SGYT 2358
Query: 1033 CDIRSLP-CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEVDP 1087
+ R + CR L LC A G+C++ S C C G T + C ++D
Sbjct: 2359 AEGRDVDECR--------MLAHLC-AHGECINSLGSFRCHCQAGYTPDATATTC-LDMDE 2408
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
C P C+ G ++C C GY +G C+D +DEC S+ C++ V
Sbjct: 2409 CSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD-LDECTSRQHNCQFLCVNTVGA 2467
Query: 1144 YLCSCPPG-TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT---- 1198
+ C CPPG T + D+C P GP C +G C + G FRC C G+T
Sbjct: 2468 FTCRCPPGFTQHHQACFDNDECSAQP----GP-CGAHGHCHNTPGSFRCECHQGFTLVSS 2522
Query: 1199 GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSG----PRCQTVLSPCESQP 1254
G CE D+NEC G H Q+ GG+RC C GF+ +C S P
Sbjct: 2523 GHGCE-DVNEC-DGPHRCQHG---CQNQLGGYRCSCPQGFTQHSQWAQCVDENECALSPP 2577
Query: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPR----CERVARSCRELQCPVGVPCQQTPRG 1310
CR + G F C C F + C+ V C + P C TP G
Sbjct: 2578 TCGSASCRNTLGG-----FRCVCPSGFDFDQALGGCQEVDE-CAGRRGPCSYSCANTPGG 2631
Query: 1311 PRCACPPG 1318
C CP G
Sbjct: 2632 FLCGCPQG 2639
Score = 425 bits (1093), Expect = e-118
Identities = 470/1624 (28%), Positives = 622/1624 (38%), Gaps = 335/1624 (20%)
Query: 31 LLLAGPGAAAPPC--LDGSPCA----NGGRCTQLPSREAACLCPPGWVGERCQLEDPCHS 84
L G AP C GS C+ NGG C R A+CLC G+ G C
Sbjct: 100 LCTCADGTLAPSCGVSRGSGCSVSCMNGGTC-----RGASCLCQKGYTGTVC-------G 147
Query: 85 GPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP---DPCLSSP----CAH---GARC 134
P RG G R C C GF GP C PC C H G C
Sbjct: 148 QPICDRGCHNGGRCIGPNR--CACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVC 205
Query: 135 S-------VGPDGRFLCSCPPGYQGRSCR------------SDVDECRVGEPCRHGGTCL 175
+ VG C P Q CR DVDEC+ GG+C+
Sbjct: 206 TKALCCATVGRAWGLPCELCPA-QPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCV 264
Query: 176 NTPGSFRCQCPAGY----TGPLCENPAVPCAPSP-------------------CRNGGTC 212
N GSF C+CP G+ + CE+ S C + G C
Sbjct: 265 NMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRC 324
Query: 213 RQSGDLTYDCACLPGFEGQN-CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
+G + C E Q C + PGH L G G N PP
Sbjct: 325 WAAGPVPELCPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMG---PP------- 374
Query: 272 TEDVDECQLQPNACHNGGTCFNTLG-GHSCVCVNGWTGESCSQNIDDCA--TAVCFHGAT 328
+ +L P+ G +LG G+S + + +Q ID C T +C +G
Sbjct: 375 ---LGPARLNPHGSDARG--IPSLGPGNSNIGT-----ATLNQTIDICRHFTNLCLNG-R 423
Query: 329 CHDRVASFYCACPMGKTGLL---CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF-- 383
C +S+ C C +G T + C D C S+PCH D + G C C PGF
Sbjct: 424 CLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPCHHG---DCVNIPGTYHCRCYPGFQA 480
Query: 384 --TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECLS 437
T AC DVDEC + C HLGRCVNT+GSF C C G+ G C D NEC +
Sbjct: 481 TPTRQAC-VDVDECIVSGGLC-HLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECAT 537
Query: 438 GPCRNQATCLDRIGQFTCICMAGFT----GTYCEVDIDECQS-SPCVNGGVCKDRVNGFS 492
CL+ G F+C+C GF G YC +DIDECQ+ CVNG C + F
Sbjct: 538 STMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYC-MDIDECQTPGICVNGH-CTNTEGSFR 595
Query: 493 CTCPSGFS-GSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTL-----CDRNV 546
C C G + G+ ++ VD + C + + CA F GT+ C N
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIE--------KGSCARPFPGTVTKSECCCANP 647
Query: 547 DDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKY 604
D +PC D A F C+ G T ++EC P C + G C +L Y
Sbjct: 648 DHGFGEPCQLCPAKDS-AEFQALCSSGLGITTDGRDINECALDPEVCAN-GVCENLRGSY 705
Query: 605 LCRC----PSGTTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF----TGPLC 654
C C +G +G +C ++D+CA N C G C++ Y C C PGF +C
Sbjct: 706 RCVCNLGYEAGASGKDC-TDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEIC 764
Query: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGS-LPP---LCLPPSH-----PCAHEPCS 705
+++EC SSPC G C + + C C PGS L P CL + C
Sbjct: 765 K-DVDECLSSPC-VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCE 822
Query: 706 HGI---------CYDAPGGFRCVCEPGWSGPRCSQSLAR---------DACESQP-CRAG 746
+ C + CE P C++ AR + CES P
Sbjct: 823 VNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCPN 882
Query: 747 GTCSSDGMGFHCTCPPGV----QGRQC--ELLSPC----TPNPC---------------- 780
G C + F C CP G+ GR C L PC + C
Sbjct: 883 GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCS 942
Query: 781 ---EHGGRCESAPG--QLPVCS-CPQG--------WQGPRCQQDVDEC-AGPAPCGPHGI 825
G CE+ P L S CP+G G +DV+EC P C HG
Sbjct: 943 IGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLC-THGT 1001
Query: 826 CTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCLNG-GSCQDGVGSFSCSCLPGFAG 881
C N GSF C C GG+ + ++ DI++C +P L G G+C + GSF C C PG+
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYES 1061
Query: 882 ----PRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPS 931
+ DVDEC +P C GTCT+ S+ C CPPG+ G CE D+ +CS S
Sbjct: 1062 GFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLS 1120
Query: 932 -SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV---CSAAHPGFRCT 987
G CV+ + +F C C G+ + +GG C +RC+
Sbjct: 1121 DGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCS 1180
Query: 988 CLESFT----GPQCQTLVDWCSRQP--CQNGGRCVQTGAY-CLCPPGWSGRLCDIRSLPC 1040
C + ++ G C VD C P C G G + CLC G+ +
Sbjct: 1181 CGQGYSLMPDGRACAD-VDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDV 1239
Query: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVDPCL--AQPCQH 1095
E + L G C + S C C G R G+ +VD C C
Sbjct: 1240 DECDLNPHICLH------GDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDS 1293
Query: 1096 GGTCRGYMGGYMCECLPGYNGDNCE-DDVDECASQP--CQHGGSCIDLVARYLCSCPPGT 1152
+C G + C CLPG+ GD E D+DEC SQ C G C+++ Y C+C G
Sbjct: 1294 HASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGF 1353
Query: 1153 L--GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGL---RCEADIN 1207
G CE + D+C L NG C++ GG+RC C G+ R D++
Sbjct: 1354 AGDGFFCE-DRDECAENVDL------CDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVD 1406
Query: 1208 ECRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRCQTVLSPCESQPCQHGGQCRP 1263
EC G A + + L G FRC+C+ G+ G C T ++ C G C
Sbjct: 1407 ECAQGNLCAFGSCENLP---GMFRCICNGGYELDRGGGNC-TDINECADPVNCINGVCIN 1462
Query: 1264 SPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPP---GLS 1320
+PG ++ C C Q F EL P GV C T R C G S
Sbjct: 1463 TPG-----SYLCSCPQDF-------------ELN-PSGVGCVDT-RAGNCFLETHDRGDS 1502
Query: 1321 GPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPE 1380
G SC + G G + ASC C+ + W P CE A
Sbjct: 1503 GISCSAEIG--VGVTRASCC--------------------CSLGRAWGNP-CELCPMANT 1539
Query: 1381 VSEEPRCPRA-ACQAKRGDQRCD--RECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLF 1437
CP Q R + EC GGDC + G QCE + L
Sbjct: 1540 TEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGS--FQCECPPGYHLS 1597
Query: 1438 NNSR 1441
++R
Sbjct: 1598 EHTR 1601
Score = 413 bits (1062), Expect = e-115
Identities = 454/1593 (28%), Positives = 609/1593 (38%), Gaps = 325/1593 (20%)
Query: 49 CANGGRCTQLPSREAACLCPPGWVGERC--------------QLEDPCHSGPCAGRGVCQ 94
C + CT P C+ PG RC +++ SG G C
Sbjct: 447 CIDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGRC- 505
Query: 95 SSVVAGTARFSCRCPRGFR----GPDCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPG 149
V F C C GF G +C + C +S C +G + DG F C C PG
Sbjct: 506 ---VNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGV--CLNEDGSFSCLCKPG 560
Query: 150 Y----QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQC----PAGYTGPLCENPAVPC 201
+ G C D+DEC+ C + G C NT GSFRCQC G G +C + V
Sbjct: 561 FLLAPGGHYC-MDIDECQTPGICVN-GHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRS 618
Query: 202 APSPCRNGGTCRQ--SGDLT-YDCACL---PGFEGQNCEVNVDDCPGH-------RCLNG 248
G+C + G +T +C C GF G+ C++ CP C +G
Sbjct: 619 TCYGAIEKGSCARPFPGTVTKSECCCANPDHGF-GEPCQL----CPAKDSAEFQALCSSG 673
Query: 249 -GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW- 306
G DG D++EC L P C N G C N G + CVC G+
Sbjct: 674 LGITTDG------------------RDINECALDPEVCAN-GVCENLRGSYRCVCNLGYE 714
Query: 307 ---TGESCSQNIDDCA--TAVCFHGATCHDRVASFYCACPMG----KTGLLCHLDDACVS 357
+G+ C+ ++D+CA + +C +G C + S+ C+CP G + +C D C+S
Sbjct: 715 AGASGKDCT-DVDECALNSLLCDNG-WCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLS 772
Query: 358 NPCHEDAICDTNPVNGRAICTCPPG------------FTGGACDQDVDE--CSIGANPCE 403
+PC +C + G C C PG T G C + E C +
Sbjct: 773 SPC-VSGVC--RNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGAS 829
Query: 404 HLGRCVNTQGSFL---CQ-------CGRGY---TGPRCETDVNECLS--GPCRNQATCLD 448
C T G+ C+ C RG+ TG C+ DVNEC S G C N C++
Sbjct: 830 LRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPN-GRCVN 887
Query: 449 RIGQFTCICMAGF----TGTYC----------EVDIDEC----------QSSPCVNGGV- 483
G F C C G +G C D DEC C G V
Sbjct: 888 TAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVW 947
Query: 484 ------CKDRVN-GFSCTCPSG--------FSGSTCQLDVDECASTP--CRNGAKCVDQP 526
C D + F+ CP G SG DV+EC P C +G C +
Sbjct: 948 GVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT-CRNTV 1006
Query: 527 DGYECRCAEGFEGTLCDRN---VDDC--SPDPCHHGRCVDGIASFSCACAPGYTG----- 576
+ C CA GF +RN +D+C SPD C G CV+ SF C C PGY
Sbjct: 1007 GSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLM 1066
Query: 577 TRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCASNP-- 628
C VDEC P CR GG C + Y C+CP G G CE +ID+C+ +
Sbjct: 1067 KNC-MDVDECARDPLLCR-GGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSLSDGL 1123
Query: 629 CTFGVCRDGINRYDCVCQPGFTGPLCN---VEINECASSPCGEGGSCVDGENGFRCLCPP 685
C G C + I + C C GF V+INEC G C++ E +RC C
Sbjct: 1124 CPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQ 1183
Query: 686 G-SLPP--LCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACE 739
G SL P C P C G C + PGG RC+C G+ + P + D C+
Sbjct: 1184 GYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDMRTCVDVDECD 1243
Query: 740 SQP-CRAGGTCSSDGMGFHCTCPPGVQGRQ----CELLSPCT--PNPCEHGGRCESAPGQ 792
P G C + F C C G R+ C + C + C+ C + PG
Sbjct: 1244 LNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGS 1303
Query: 793 LPVCSCPQGWQGPRCQ-QDVDECAGPA-PCGPHGICTNLAGSFSCTCHGGYTGPS--CDQ 848
C C GW G + D+DEC C P G C N+ GS+ CTC G+ G C +
Sbjct: 1304 FS-CRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFC-E 1361
Query: 849 DINDCDPNPCL-NGGSCQDGVGSFSCSCLPGF---AGPRCARDVDECL-SNPCGPGTCTD 903
D ++C N L + G C + G + C C GF R +DVDEC N C G+C +
Sbjct: 1362 DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCEN 1421
Query: 904 HVASFTCTCPPGY----GGFHCEQDLPDCS-PSSCFNGGTCVDGVNSFSCLCRPGY---- 954
F C C GY GG +C D+ +C+ P +C N G C++ S+ C C +
Sbjct: 1422 LPGMFRCICNGGYELDRGGGNC-TDINECADPVNCIN-GVCINTPGSYLCSCPQDFELNP 1479
Query: 955 TGAHC-QHEADPCLSRPCLHG--GVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQN 1011
+G C A C G G+ +A G T C + PC+
Sbjct: 1480 SGVGCVDTRAGNCFLETHDRGDSGISCSAEIGV------GVTRASCCCSLGRAWGNPCEL 1533
Query: 1012 GGRCVQTGAYCLCPPGWSGRLCDIRSL-----PCREAAAQIGVRLEQLCQAGGQCVDEDS 1066
T LCP G + I + C+E L LCQ GG CV+
Sbjct: 1534 CPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQE--------LPGLCQ-GGDCVNTFG 1584
Query: 1067 SHYCVCPEG-RTGSHCE--QEVDPCLAQPCQHG-GTCRGYMGGYMCECLPGY----NGDN 1118
S C CP G H +++D C G GTC +G Y C C Y G+N
Sbjct: 1585 SFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNN 1644
Query: 1119 CEDDVDECASQPCQHGGSCIDLVA----RYLCSCP--------------PGTLG----VL 1156
C D + + G+C + +A R +C C P + +L
Sbjct: 1645 CMDMRKSVCFR--HYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQIL 1702
Query: 1157 CEINE----DDCGPGPPLDSG-----PRCLHNGTCVDLVGGFRCTCPPGYTG----LRCE 1203
C D G PLD P NG C++ +G FRC CP G+ L CE
Sbjct: 1703 CGNQAPGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACE 1762
Query: 1204 ADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS---GPRCQTVLSPCESQP--CQHG 1258
D++EC S DC+ P G +RC C G+ G C + C P C H
Sbjct: 1763 -DVDECGSRESPCQQNADCINIP-GSYRCKCTRGYKLSPGGAC-VGRNECREIPNVCSH- 1818
Query: 1259 GQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPG 1318
G C + G ++ C C + F + + E C + P G C
Sbjct: 1819 GDCMDTEG-----SYMCLCHRGFQASADQTLCMDIDE--------CDRQPCG-NGTCKNI 1864
Query: 1319 LSGPSCRSFPGSPPGASNASCA---AAPCLHGGSCR---PAPLAPFFRCACAQGW----T 1368
+ +C FPG N C L G CR A F C C G+
Sbjct: 1865 IGSYNCLCFPGFVV-THNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTAD 1923
Query: 1369 GPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC 1401
G C +S C CQ G RC
Sbjct: 1924 GKNCVDTNEC--LSLAGTCLPGTCQNLEGSFRC 1954
Score = 410 bits (1054), Expect = e-114
Identities = 423/1438 (29%), Positives = 574/1438 (39%), Gaps = 352/1438 (24%)
Query: 40 APPCLDGSPCANGGR-------CTQLPSREAACLCPPGWVGE--RCQLEDPCHSGP--CA 88
A C D C GG C +P +C C PGWVG+ C D C S C+
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPG-SFSCRCLPGWVGDGFECHDLDECVSQEHRCS 1333
Query: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPD--------------PCLSSP------- 127
RG C + V G+ R C C +GF G D CL++P
Sbjct: 1334 PRGDCLN--VPGSYR--CTCRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCEC 1389
Query: 128 ------------------CAHGARCSVGP----DGRFLCSCPPGYQ----GRSCRSDVDE 161
CA G C+ G G F C C GY+ G +C +D++E
Sbjct: 1390 EMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINE 1448
Query: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPA-VPCAPSPCRN-----------G 209
C C +G C+NTPGS+ C CP + NP+ V C + N G
Sbjct: 1449 CADPVNCING-VCINTPGSYLCSCPQDFE----LNPSGVGCVDTRAGNCFLETHDRGDSG 1503
Query: 210 GTCRQS---GDLTYDCACLPGFE-GQNCEV-----------------------------N 236
+C G C C G G CE+ +
Sbjct: 1504 ISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILED 1563
Query: 237 VDDC---PGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT---EDVDECQLQPNACHNGGT 290
+D+C PG GG CV+ ++ C+CPP + T ED+DEC C GT
Sbjct: 1564 IDECQELPG--LCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGIC-GPGT 1620
Query: 291 CFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCF--HGATCHDRVA----SFYCACPMGK 344
C+NTLG ++CVC + + N D +VCF + TC + +A C C
Sbjct: 1621 CYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSY-- 1678
Query: 345 TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC---PPGF-----TGGACDQDVDECS 396
++ A + PC C T P++ C PGF TG D +DEC
Sbjct: 1679 -----NIGQAW-NRPCEA---CPT-PISPDYQILCGNQAPGFLTDIHTGKPLD--IDECG 1726
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPR----CETDVNECLS--GPCRNQATCLDRI 450
C + G C+N GSF C+C G+ CE DV+EC S PC+ A C++
Sbjct: 1727 EIPAICAN-GICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIP 1784
Query: 451 GQFTCICMAGFT---GTYCEVDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFSGSTCQ- 505
G + C C G+ G C V +EC+ P V + G C D + C C GF S Q
Sbjct: 1785 GSYRCKCTRGYKLSPGGAC-VGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQT 1843
Query: 506 --LDVDECASTPCRNGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDCSP---DPCHH 556
+D+DEC PC NG C + Y C C GF G D D+C+ C
Sbjct: 1844 LCMDIDECDRQPCGNGT-CKNIIGSYNCLCFPGFVVTHNGDCVD--FDECTTLVGQVCRF 1900
Query: 557 GRCVDGIASFSCACAPGYT----GTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPS 610
G C++ SF C C G+ G C +EC S C G C +L + C CP
Sbjct: 1901 GHCLNTAGSFHCLCQDGFELTADGKNCVD-TNECLSLAGTCLPG-TCQNLEGSFRCICPP 1958
Query: 611 G--TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFT----GPLC-------- 654
G +C ++ID+C+ P C FG C + + C+C PGF G C
Sbjct: 1959 GFQVQSDHC-IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFC 2017
Query: 655 ----------------NVEINECASSPCGEGGS-----CV-DGENGFRCLCP------PG 686
+ C S GEG C +G F+ LCP PG
Sbjct: 2018 FTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPG 2077
Query: 687 SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE- 739
P + CA P C++G+C + G FRC C G+S G C + D C
Sbjct: 2078 --PDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDT---DECSV 2132
Query: 740 SQPCRAGGTCSSDGMGFHCTCPPGVQG---RQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
PC GTC++ GF C C G + CE + C+ NP RC + G +C
Sbjct: 2133 GHPC-GQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEGSY-LC 2190
Query: 797 SCPQGW----QGPRCQQDVDECA-GPAPCGPHGI-CTNLAGSFSCTCHGGY-----TGPS 845
+CP G+ G C+ DVDECA G C G+ C NL G+F+C C G +G
Sbjct: 2191 TCPAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEG 2249
Query: 846 CDQDINDCDPNP--CLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC------- 896
C D N+C P C+NG C + GSF C C GF + + PC
Sbjct: 2250 CTDD-NECHAQPDLCVNG-RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQT 2307
Query: 897 ---GPGTCTDHVASFTCTCPPGYG-GFHCE------------------------QDLPDC 928
+ ++ V C C G G G CE +D+ +C
Sbjct: 2308 MCRSLSSSSEAVTRAECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDEC 2367
Query: 929 SPSS--CFNGGTCVDGVNSFSCLCRPGYTG---AHCQHEADPC--LSRPCLHGGVCSAAH 981
+ C +G C++ + SF C C+ GYT A + D C + +PC +C
Sbjct: 2368 RMLAHLCAHG-ECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTF--LCKNTK 2424
Query: 982 PGFRCTCLESFT----GPQCQTLVDWCSRQP-CQNGGRCVQT-GAY-CLCPPGWSGRLCD 1034
F C+C + G C+ L + SRQ CQ CV T GA+ C CPPG++
Sbjct: 2425 GSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQF--LCVNTVGAFTCRCPPGFTQH--H 2480
Query: 1035 IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT----GSHCEQEVDPCLA 1090
E +AQ G C A G C + S C C +G T G CE +V+ C
Sbjct: 2481 QACFDNDECSAQPGP-----CGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDG 2534
Query: 1091 -QPCQHGGTCRGYMGGYMCECLPGYNGDN----CEDDVDECASQPCQHGG-SCIDLVARY 1144
CQHG C+ +GGY C C G+ + C D+ +ECA P G SC + + +
Sbjct: 2535 PHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCVDE-NECALSPPTCGSASCRNTLGGF 2591
Query: 1145 LCSCPPG-----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY 1197
C CP G LG E++E GP C ++ C + GGF C CP GY
Sbjct: 2592 RCVCPSGFDFDQALGGCQEVDECAGRRGP-------CSYS--CANTPGGFLCGCPQGY 2640
Score = 404 bits (1038), Expect = e-112
Identities = 481/1744 (27%), Positives = 647/1744 (37%), Gaps = 379/1744 (21%)
Query: 43 CLDGSPCANGGRCTQ----LPSREAACLCPPGWVG----------ERCQLEDPCHSGPCA 88
C+D + CA C +CLC PG++ + CQ C +G C
Sbjct: 529 CVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCT 588
Query: 89 G-----RGVCQSSVVAGT---------ARFSC-------RCPRGFRGPD------CSLPD 121
R C + GT R +C C R F G C+ PD
Sbjct: 589 NTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPD 648
Query: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSF 181
PC C F C G + D++EC + G C N GS+
Sbjct: 649 HGFGEPCQ---LCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSY 705
Query: 182 RCQCPAGY----TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFE-GQNCEV- 235
RC C GY +G C + S + G C+ S +Y C+C PGF Q+ E+
Sbjct: 706 RCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSPG-SYSCSCPPGFHFWQDTEIC 764
Query: 236 -NVDDCPGHRCLNGGTCVDGVNTYNCQCPP----EWTGQFCTEDV----------DECQL 280
+VD+C C++G C + +Y C+C P + +G FC + C++
Sbjct: 765 KDVDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEV 823
Query: 281 QPNACHNGGTCFNTLG---GHSC-------VCVNGW---TGESCSQNIDDCAT--AVCFH 325
C TLG G C C G+ TG +C ++++C + VC +
Sbjct: 824 NLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVNECESFPGVCPN 882
Query: 326 GATCHDRVASFYCACPMGKTGLLCHLDDACVS---NPCH----EDAICDTNPVNGRA-IC 377
G C + SF C CP G +L CV PC ED T P R +C
Sbjct: 883 GR-CVNTAGSFRCECPEGL--MLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVC 939
Query: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY------TGPRCETD 431
C G G EC +P + + + LC G G+ +G D
Sbjct: 940 CCSIGAVWGV------ECEACPDP-------ESLEFASLCPRGLGFASRDFLSGRPFYKD 986
Query: 432 VNEC--LSGPCRNQATCLDRIGQFTCICMAGFTGTYCE---VDIDECQSSPCVNG-GVCK 485
VNEC G C + TC + +G F C C GF E DIDEC+ SP + G G C
Sbjct: 987 VNECKVFPGLCTH-GTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCV 1045
Query: 486 DRVNGFSCTC----PSGFSGSTCQLDVDECASTP--CRNGAKCVDQPDGYECRCAEGFE- 538
+ F C C SGF +DVDECA P CR G C + Y+C+C G E
Sbjct: 1046 NTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGT-CTNTDGSYKCQCPPGHEL 1104
Query: 539 ---GTLCDRNVDDCSPDP--CHHGRCVDGIASFSCACAPGYTGTRCES---QVDECRSQP 590
GT C+ ++D+CS C HG+CV+ I +F C+C G+ T ++ECR Q
Sbjct: 1105 TAKGTACE-DIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQN 1163
Query: 591 CRHGGKCLDLVDKYLCRCPSGTT----GVNCEVNIDDCASNP--CTFGVCRDGINRYDCV 644
C++ Y C C G + G C ++D+C NP C G C + + C+
Sbjct: 1164 GGCDVHCINTEGSYRCSCGQGYSLMPDGRAC-ADVDECEENPRVCDQGHCTNMPGGHRCL 1222
Query: 645 CQPGFTGP----LCNVEINECASSP--CGEGGSCVDGENGFRCLCPPGSLPPL------- 691
C GF C V+++EC +P C G C + + F C C G +
Sbjct: 1223 CYDGFMATPDMRTC-VDVDECDLNPHICLHG-DCENTKGSFVCHCQLGYMVRKGATGCSD 1280
Query: 692 ---CLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGP--RCSQSLARDACESQP--CR 744
C H C SH C + PG F C C PGW G C D C SQ C
Sbjct: 1281 VDECEVGGHNCD----SHASCLNIPGSFSCRCLPGWVGDGFECHDL---DECVSQEHRCS 1333
Query: 745 AGGTCSSDGMGFHCTCPPGVQGRQ--CELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQ 800
G C + + CTC G G CE C N C++G +C +APG C C
Sbjct: 1334 PRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVDLCDNG-QCLNAPGGYR-CECEM 1391
Query: 801 GW---QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCDQDIND- 852
G+ + R QDVDECA C G C NL G F C C+GGY G +C DIN+
Sbjct: 1392 GFDPTEDHRACQDVDECAQGNLCA-FGSCENLPGMFRCICNGGYELDRGGGNCT-DINEC 1449
Query: 853 -----CDPNPCLN------------------GGSCQD----------------------- 866
C C+N G C D
Sbjct: 1450 ADPVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAE 1509
Query: 867 ---GVGSFSCSCLPGFA-GPRCA-----------------------------RDVDECLS 893
GV SC C G A G C D+DEC
Sbjct: 1510 IGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQE 1569
Query: 894 NP--CGPGTCTDHVASFTCTCPPGYGGFH----CEQDLPDCSPSSCFNG-GTCVDGVNSF 946
P C G C + SF C CPPGY CE D+ +CS S G GTC + + ++
Sbjct: 1570 LPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICE-DIDECSTHSGICGPGTCYNTLGNY 1628
Query: 947 SCLCRPGYTGAHCQHEADPCLSRPCL--HGGVCS--AAHPGFRCTCLESFTGPQCQTLVD 1002
+C+C Y + + C + G C A R C S+ Q
Sbjct: 1629 TCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQA----- 1683
Query: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRS---LPCREAAAQIGVRLEQLCQAGG 1059
W +PC+ + LC G L DI + L E + +C A G
Sbjct: 1684 W--NRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECG-----EIPAIC-ANG 1735
Query: 1060 QCVDEDSSHYCVCPEGRTGSH----CEQEVDPCLAQ--PCQHGGTCRGYMGGYMCECLPG 1113
C+++ S C CP G + CE +VD C ++ PCQ C G Y C+C G
Sbjct: 1736 ICINQIGSFRCECPAGFNYNSILLACE-DVDECGSRESPCQQNADCINIPGSYRCKCTRG 1794
Query: 1114 YN---GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCPPGTLG----VLCEINEDDC 1164
Y G C +EC P C HG C+D Y+C C G LC ++ D+C
Sbjct: 1795 YKLSPGGACVGR-NECREIPNVCSHG-DCMDTEGSYMCLCHRGFQASADQTLC-MDIDEC 1851
Query: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLR---CEADINECRSGACHAAHTRD 1221
P NGTC +++G + C C PG+ C D +EC +
Sbjct: 1852 DRQP--------CGNGTCKNIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVCRFGH 1902
Query: 1222 CLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC 1277
CL + G F CLC GF G C + C S G C P +F C C
Sbjct: 1903 CL-NTAGSFHCLCQDGFELTADGKNCVDT-NECLSL----AGTCLPGTCQNLEGSFRCIC 1956
Query: 1278 AQPFW--GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPG--LSGPSCRSFPGSPPG 1333
F C + E + C +P +C CPPG LS R F
Sbjct: 1957 PPGFQVQSDHCIDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFD----- 2011
Query: 1334 ASNASCAAAPCLHGGSCRPAPLA---PFFRCACA----QGWTGPRCEAPAAAPEVSEEPR 1386
+ C G C P A RC C+ +GW P CE + +
Sbjct: 2012 TRQSFCFTR--FEAGKCS-VPKAFNTTKTRCCCSKRPGEGWGDP-CELCPQEGSAAFQEL 2067
Query: 1387 CPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSV---GDPWRQCEALQCWRL-FNNSRC 1442
CP A G + N C + G C+ V D +CE + L F C
Sbjct: 2068 CPFGH-GAVPGPDDSREDVNE--CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Query: 1443 DPACSSPACLYDNFDCHAGGR--ERTCNPV---YEKYCADHFADGRCDQGCNTEECGWDG 1497
D +C G + TC V +E CAD F G + +EC +
Sbjct: 2125 ----------VDTDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNP 2174
Query: 1498 LDCA 1501
L CA
Sbjct: 2175 LLCA 2178
Score = 375 bits (963), Expect = e-103
Identities = 419/1520 (27%), Positives = 595/1520 (39%), Gaps = 330/1520 (21%)
Query: 104 FSCRCPRGF----RGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-- 157
+ C C G+ RG +C D C SSPC HG ++ G + C C PG+Q R
Sbjct: 431 YRCECNVGYTQDVRG-ECIDVDECTSSPCHHGDCVNI--PGTYHCRCYPGFQATPTRQAC 487
Query: 158 -DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY----TGPLCENPAVPCAPSPCRNGGTC 212
DVDEC V H G C+NT GSF+C C AG+ G C + + C NG
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCL 547
Query: 213 RQSGDLTYDCACLPGF---EGQNCEVNVDDC--PGHRCLNGGTCVDGVNTYNCQC----P 263
+ G ++ C C PGF G + +++D+C PG C+N G C + ++ CQC
Sbjct: 548 NEDG--SFSCLCKPGFLLAPGGHYCMDIDECQTPG-ICVN-GHCTNTEGSFRCQCLGGLA 603
Query: 264 PEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT---GESCSQNIDDCAT 320
G+ C + H TC+ + SC T E C N D
Sbjct: 604 VGTDGRVCVD-----------THVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFG 652
Query: 321 AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCP 380
C C+ +G T +++ + + +C+ + G C C
Sbjct: 653 EPCQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCEN--LRGSYRCVCN 710
Query: 381 PGFTGGACDQ---DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY---TGPRCETDVNE 434
G+ GA + DVDEC++ + C++ G C N+ GS+ C C G+ DV+E
Sbjct: 711 LGYEAGASGKDCTDVDECALNSLLCDN-GWCQNSPGSYSCSCPPGFHFWQDTEICKDVDE 769
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGF----TGTY-----------------CEVDI--- 470
CLS PC + C + G +TC C G +GT+ CEV++
Sbjct: 770 CLSSPCVS-GVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGA 828
Query: 471 ---DECQSSPCVNGGVCKDRVNGFSCTCPSGF---SGSTCQLDVDECASTP--CRNGAKC 522
EC ++ G +R C GF +G TC DV+EC S P C NG +C
Sbjct: 829 SLRSECCATLGAAWGSPCERCE-IDPACARGFARMTGVTCD-DVNECESFPGVCPNG-RC 885
Query: 523 VDQPDGYECRCAEGF----EGTLC-DRNVDDC----SPDPCHHGRCVDGIASFS-CACAP 572
V+ + C C EG G LC D ++ C D C G + G C C+
Sbjct: 886 VNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDEC--GVTLPGKYRMDVCCCSI 943
Query: 573 GYT-GTRCES--------------------------------QVDECRSQP--CRHGGKC 597
G G CE+ V+EC+ P C H G C
Sbjct: 944 GAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTH-GTC 1002
Query: 598 LDLVDKYLCRCPSG----TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFTG 651
+ V + C C G NC +ID+C +P C G C + ++C C PG+
Sbjct: 1003 RNTVGSFHCACAGGFALDAQERNC-TDIDECRISPDLCGQGTCVNTPGSFECECFPGYES 1061
Query: 652 PLC----NVEINECASSP-CGEGGSCVDGENGFRCLCPPG---SLPPLCLPPSHPCAHEP 703
++++ECA P GG+C + + ++C CPPG + C+
Sbjct: 1062 GFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACEDIDECSLSD 1121
Query: 704 --CSHGICYDAPGGFRCVCEPGW-SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC 760
C HG C + G F+C C G+ S P + + C Q C + + C+C
Sbjct: 1122 GLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSC 1181
Query: 761 PPGV----QGRQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQGWQGP---RCQQDV 811
G GR C + C NP C+ G C + PG C C G+ R DV
Sbjct: 1182 GQGYSLMPDGRACADVDECEENPRVCDQ-GHCTNMPGG-HRCLCYDGFMATPDMRTCVDV 1239
Query: 812 DEC-AGPAPCGPHGICTNLAGSFSCTCHGGY---TGPSCDQDINDCD--PNPCLNGGSCQ 865
DEC P C HG C N GSF C C GY G + D+++C+ + C + SC
Sbjct: 1240 DECDLNPHIC-LHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCL 1298
Query: 866 DGVGSFSCSCLPGFAGPRC-ARDVDECLS--NPCGP-GTCTDHVASFTCTCPPGYG--GF 919
+ GSFSC CLPG+ G D+DEC+S + C P G C + S+ CTC G+ GF
Sbjct: 1299 NIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAGDGF 1358
Query: 920 HCEQDLPDCSPS-SCFNGGTCVDGVNSFSCLCRPGY--TGAH--CQHEADPCLSRPCLHG 974
CE D +C+ + + G C++ + C C G+ T H CQ + D C
Sbjct: 1359 FCE-DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQ-DVDECAQGNLCAF 1416
Query: 975 GVCSAAHPGFRCTCLESFT----GPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGW 1028
G C FRC C + G C + + C N G C+ T G+Y C CP +
Sbjct: 1417 GSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCIN-GVCINTPGSYLCSCPQDF 1475
Query: 1029 ----SGRLC-DIRSLPC-----------REAAAQIGV---RLEQLCQAGGQ-------CV 1062
SG C D R+ C +A+IGV R C G C
Sbjct: 1476 ELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCP 1535
Query: 1063 DEDSSHY-CVCPEGRTGSHCE-----QEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGY 1114
+++ Y +CP G +++D C P CQ GG C G + CEC PGY
Sbjct: 1536 MANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQ-GGDCVNTFGSFQCECPPGY 1594
Query: 1115 NGDN----CEDDVDECASQPCQHG-GSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP 1169
+ CE D+DEC++ G G+C + + Y C CP L V
Sbjct: 1595 HLSEHTRICE-DIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQV-------------- 1639
Query: 1170 LDSGPRCL----------HNGTCVDLVGGFRCT--------------------CP----- 1194
+ G C+ +NGTC + + F T CP
Sbjct: 1640 -NGGNNCMDMRKSVCFRHYNGTCQNEL-AFNVTRKMCCCSYNIGQAWNRPCEACPTPISP 1697
Query: 1195 ----------PGY-----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239
PG+ TG DI+EC G A + G FRC C AGF+
Sbjct: 1698 DYQILCGNQAPGFLTDIHTGK--PLDIDEC--GEIPAICANGICINQIGSFRCECPAGFN 1753
Query: 1240 GPRCQTVLSPCE--------SQPCQHGGQCRPSPGPGGGLTFTCHCAQPF-WGPRCERVA 1290
++L CE PCQ C PG ++ C C + + P V
Sbjct: 1754 ---YNSILLACEDVDECGSRESPCQQNADCINIPG-----SYRCKCTRGYKLSPGGACVG 1805
Query: 1291 RS-CRELQ--CPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHG 1347
R+ CRE+ C G C T C C G + ++ C PC
Sbjct: 1806 RNECREIPNVCSHG-DCMDTEGSYMCLCHRGFQASADQTL-----CMDIDECDRQPC-GN 1858
Query: 1348 GSCRPAPLAPFFRCACAQGW 1367
G+C+ + + C C G+
Sbjct: 1859 GTCK--NIIGSYNCLCFPGF 1876
Score = 366 bits (940), Expect = e-100
Identities = 423/1469 (28%), Positives = 551/1469 (37%), Gaps = 318/1469 (21%)
Query: 185 CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHR 244
CP T P VP C G C Q C C G +C V+
Sbjct: 69 CPGWRTFPGRSQCVVPICRRACGEG-FCSQPNL----CTCADGTLAPSCGVSRGSGCSVS 123
Query: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVN 304
C+NGGTC +C C +TG C + + + CHNGG C +G + C CV
Sbjct: 124 CMNGGTCRGA----SCLCQKGYTGTVCGQPICD-----RGCHNGGRC---IGPNRCACVY 171
Query: 305 GWTGESCSQNIDDCATAVCFHGAT---CHDRVASFYCA-----CPMGKT-GLLCHLDDAC 355
G+ G C + D T CF C ++ C +G+ GL C L A
Sbjct: 172 GFMGPQCER---DYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPA- 227
Query: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSF 415
+PC I P GAC QDVDEC C+ G CVN GSF
Sbjct: 228 QPHPCRRGFI---------------PNIHTGAC-QDVDECQAVPGLCQG-GSCVNMVGSF 270
Query: 416 LCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTY----CEVDID 471
C+C G+ + +G C + F C G Y C D
Sbjct: 271 HCRCPVGHRLSDSSAACEDYRAGACFSVL--------FGGRCAGDLAGHYTRRQCCCDRG 322
Query: 472 ECQSSPCVNGGVCKDR-VNGFSCTC----------PSGFSGSTCQLDVDECASTPCRNGA 520
C ++ V +C R N F C P F G L P A
Sbjct: 323 RCWAAGPVPE-LCPPRGSNEFQQLCAQRLPLLPGHPGLFPGL---LGFGSNGMGPPLGPA 378
Query: 521 KCVDQPDGYECRCAEGFE------GTLC-DRNVDDCS--PDPCHHGRCVDGIASFSCACA 571
+ P G + R GT ++ +D C + C +GRC+ +S+ C C
Sbjct: 379 RL--NPHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLNGRCLPTPSSYRCECN 436
Query: 572 PGYT-GTRCES-QVDECRSQPCRHGGKCLDLVDKYLCRCPSG---TTGVNCEVNIDDC-- 624
GYT R E VDEC S PC HG C+++ Y CRC G T V++D+C
Sbjct: 437 VGYTQDVRGECIDVDECTSSPCHHGD-CVNIPGTYHCRCYPGFQATPTRQACVDVDECIV 495
Query: 625 ASNPCTFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGENGFR 680
+ C G C + + CVC GF G C V+ NECA+S G C++ + F
Sbjct: 496 SGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDGSFS 554
Query: 681 CLCPPGSLPPLCLPPSHPC-----AHEP--CSHGICYDAPGGFRCVC----EPGWSGPRC 729
CLC PG L P H C P C +G C + G FRC C G G C
Sbjct: 555 CLCKPGFL---LAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC 611
Query: 730 SQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG--GRCE 787
+ R C + G+C+ P V +C C NP +HG C+
Sbjct: 612 VDTHVRSTCYGAIEK--GSCARP-------FPGTVTKSEC-----CCANP-DHGFGEPCQ 656
Query: 788 SAPGQLPV---CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--- 841
P + C G +D++ECA +G+C NL GS+ C C+ GY
Sbjct: 657 LCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAG 716
Query: 842 -TGPSCDQDINDCDPNPCL-NGGSCQDGVGSFSCSCLPGF---AGPRCARDVDECLSNPC 896
+G C D+++C N L + G CQ+ GS+SCSC PGF +DVDECLS+PC
Sbjct: 717 ASGKDCT-DVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPC 775
Query: 897 GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNG--GTCVDGVNSFSCLCRPGY 954
G C + S+TC C PG D S + C + GTC + C
Sbjct: 776 VSGVCRNLAGSYTCKCGPG--------SRLDPSGTFCLDSTKGTC--WLKIQESRCEVNL 825
Query: 955 TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCT-CLESFTGPQCQTLVDWCSRQP--CQN 1011
GA + E C + G C C TG C V+ C P C N
Sbjct: 826 QGASLRSEC--CATLGAAWGSPCERCEIDPACARGFARMTGVTCDD-VNECESFPGVCPN 882
Query: 1012 GGRCVQT-GAY-CLCPPGW----SGRLC-DIRSLPC--REAAAQIGV------RLEQLCQ 1056
GRCV T G++ C CP G SGRLC D+R PC R + GV R++ C
Sbjct: 883 -GRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCC 941
Query: 1057 AGG--------QCVDEDSSHYC-VCPEG--------RTGSHCEQEVDPCLAQP--CQHG- 1096
+ G C D +S + +CP G +G ++V+ C P C HG
Sbjct: 942 SIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT 1001
Query: 1097 ----------------------------------------GTCRGYMGGYMCECLPGYNG 1116
GTC G + CEC PGY
Sbjct: 1002 CRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGTCVNTPGSFECECFPGYES 1061
Query: 1117 -----DNCEDDVDECASQPCQ-HGGSCIDLVARYLCSCPPG----TLGVLCEINEDDCGP 1166
NC DVDECA P GG+C + Y C CPPG G CE + D+C
Sbjct: 1062 GFMLMKNCM-DVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACE-DIDECSL 1119
Query: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE---ADINECR--SGAC--HAAHT 1219
L C H G CV+++G F+C+C G+ DINECR +G C H +T
Sbjct: 1120 SDGL-----CPH-GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINT 1173
Query: 1220 RDCLQDPGGGFRCLCHAGFS----GPRCQTVLSPCESQP--CQHGGQCRPSPGPGGGLTF 1273
G +RC C G+S G C V CE P C G C PG L +
Sbjct: 1174 E-------GSYRCSCGQGYSLMPDGRACADV-DECEENPRVCDQ-GHCTNMPGGHRCLCY 1224
Query: 1274 TCHCAQPFWGPRCERVARSCREL-QCPVGV------PCQQTPRGPRCACPPGL----SGP 1322
A P R+C ++ +C + C+ T C C G
Sbjct: 1225 DGFMATP--------DMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGAT 1276
Query: 1323 SCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVS 1382
C G N C SC P + F C C GW G E VS
Sbjct: 1277 GCSDVDECEVGGHN-------CDSHASCLNIPGS--FSCRCLPGWVGDGFECHDLDECVS 1327
Query: 1383 EEPRC-PRAACQAKRGDQRCDRECNSPGCGW---DGGDCSLSVGDPWRQCEALQCWRLFN 1438
+E RC PR C G RC G G+ D +C+ +V C+ QC
Sbjct: 1328 QEHRCSPRGDCLNVPGSYRCTCRQGFAGDGFFCEDRDECAENVD----LCDNGQCLNAPG 1383
Query: 1439 NSRC------DPACSSPACLYDNFDCHAG 1461
RC DP AC D +C G
Sbjct: 1384 GYRCECEMGFDPTEDHRAC-QDVDECAQG 1411
Score = 351 bits (900), Expect = 5e-96
Identities = 295/969 (30%), Positives = 402/969 (41%), Gaps = 173/969 (17%)
Query: 121 DPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRSCR---SDVDECRVGE-PCRHGGTC 174
D C P CA+G + G F C CP G+ S DVDEC E PC+ C
Sbjct: 1723 DECGEIPAICANGI--CINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADC 1780
Query: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCA--------PSPCRNGGTCRQSGDLTYDCACLP 226
+N PGS+RC+C GY +P C P+ C +G G +Y C C
Sbjct: 1781 INIPGSYRCKCTRGYK----LSPGGACVGRNECREIPNVCSHGDCMDTEG--SYMCLCHR 1834
Query: 227 GFEG---QNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEW--TGQFCTEDVDECQLQ 281
GF+ Q +++D+C C NG TC + + +YNC C P + T D DEC
Sbjct: 1835 GFQASADQTLCMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTL 1893
Query: 282 PNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQNIDDCATAVCFHGATCHDRVASFY 337
G C NT G C+C +G+ G++C + + A TC + SF
Sbjct: 1894 VGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFR 1953
Query: 338 CACPMGKTGLLCHLDDACVSNPCHED------AICDTNPVNGRAICTCPPGFT----GGA 387
C CP G H D + C E+ C +P G C CPPGF G
Sbjct: 1954 CICPPGFQVQSDHCIDI---DECSEEPNLCLFGTCTNSP--GSFQCLCPPGFVLSDNGHR 2008
Query: 388 CDQ----------DVDECSIG--------------------ANPCEHLGRCVNTQGSFLC 417
C + +CS+ +PCE + + LC
Sbjct: 2009 CFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELC 2068
Query: 418 QCGRGYT-GPR-CETDVNECLSGP--CRNQATCLDRIGQFTCICMAG----FTGTYCEVD 469
G G GP DVNEC P C N C++ G F C C G FTG C VD
Sbjct: 2069 PFGHGAVPGPDDSREDVNECAENPGVCTN-GVCVNTDGSFRCECPFGYSLDFTGINC-VD 2126
Query: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGS---TCQLDVDECASTPCRNGAKCVDQP 526
DEC G C + + GF C C GF TC+ D+DEC+ P +C +
Sbjct: 2127 TDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCE-DIDECSLNPLLCAFRCHNTE 2185
Query: 527 DGYECRCAEGF----EGTLCDRNVDDCSP--DPCHHG--RCVDGIASFSCACAPGY---- 574
Y C C G+ +G +C R+VD+C+ CH C + I +F+C C PG
Sbjct: 2186 GSYLCTCPAGYTLREDGAMC-RDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLP 2244
Query: 575 -TGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTF 631
+G C +EC +QP C +G +C++ + C C G D PC
Sbjct: 2245 GSGEGCTDD-NECHAQPDLCVNG-RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFA 2302
Query: 632 GV----CR------DGINRYDCVCQPGFT-GPLCNVEINECASSPCGEGGSCVDGENGFR 680
V CR + + R +C C G GP C + C + G + +R
Sbjct: 2303 EVLQTMCRSLSSSSEAVTRAECCCGGGRGWGPRCEL----CP----------LPGTSAYR 2348
Query: 681 CLCPPGS---LPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS-LARD 736
LCP GS + AH C+HG C ++ G FRC C+ G++ + + L D
Sbjct: 2349 KLCPHGSGYTAEGRDVDECRMLAHL-CAHGECINSLGSFRCHCQAGYTPDATATTCLDMD 2407
Query: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPCTPNPCEHGGRCESAPGQ 792
C P C + F C+CP G GR C+ L CT C + G
Sbjct: 2408 ECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQFLCVNTVGA 2467
Query: 793 LPVCSCPQGW-QGPRCQQDVDEC-AGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSC 846
C CP G+ Q + D DEC A P PCG HG C N GSF C CH G+T G C
Sbjct: 2468 F-TCRCPPGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC 2526
Query: 847 DQDINDCD-PNPCLNGGSCQDGVGSFSCSCLPGFA----GPRCARDVDECLSNP--CGPG 899
+D+N+CD P+ C +G CQ+ +G + CSC GF +C D +EC +P CG
Sbjct: 2527 -EDVNECDGPHRCQHG--CQNQLGGYRCSCPQGFTQHSQWAQCV-DENECALSPPTCGSA 2582
Query: 900 TCTDHVASFTCTCPPGY------GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 953
+C + + F C CP G+ GG Q++ +C+ +C + F C C G
Sbjct: 2583 SCRNTLGGFRCVCPSGFDFDQALGGC---QEVDECAGRRGPCSYSCANTPGGFLCGCPQG 2639
Query: 954 YTGA---HC 959
Y A HC
Sbjct: 2640 YFRAGQGHC 2648
Score = 91.3 bits (225), Expect = 1e-17
Identities = 149/601 (24%), Positives = 190/601 (31%), Gaps = 133/601 (22%)
Query: 946 FSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCS 1005
F C PG+ + + + R G CS + CTC + P C
Sbjct: 64 FHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPN---LCTCADGTLAPSCGVSRGSGC 120
Query: 1006 RQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
C NGG C GA CLC G++G + C + G C GG+C+ +
Sbjct: 121 SVSCMNGGTC--RGASCLCQKGYTGTV-------CGQPICDRG------CHNGGRCIGPN 165
Query: 1066 SSHYCVCPEGRTGSHCEQE--VDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
C C G G CE++ PC Q G C+ + G +C C V
Sbjct: 166 R---CACVYGFMGPQCERDYRTGPCFGQVGPEG--CQHQLTGLVC------TKALCCATV 214
Query: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTL--GVLCEINEDDCGPGPPLDSGPRCLHNGT 1181
PC+ LC P G + I+ C + P G+
Sbjct: 215 GRAWGLPCE------------LCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGS 262
Query: 1182 CVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAA-HTRDCLQDPGGGF---RCLCHAG 1237
CV++VG F C CP G+ A + R+GAC + C D G + +C C G
Sbjct: 263 CVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRG 322
Query: 1238 FSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQ 1297
RC E P P G F CAQ P L
Sbjct: 323 ----RCWAAGPVPELCP------------PRGSNEFQQLCAQRL--PLLPGHPGLFPGL- 363
Query: 1298 CPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAP-----CLH------ 1346
G P GP P G R P PG SN A C H
Sbjct: 364 LGFGSNGMGPPLGPARLNP---HGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCL 420
Query: 1347 GGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECN 1406
G C P P + +RC C G+T Q RG+ EC
Sbjct: 421 NGRCLPTPSS--YRCECNVGYT------------------------QDVRGECIDVDECT 454
Query: 1407 SPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPAC-SSPACLYDNFDCHAGGRER 1465
S C GDC G C +C+ F + AC C+ CH G
Sbjct: 455 SSPC--HHGDCVNIPGT--YHC---RCYPGFQATPTRQACVDVDECIVSGGLCHLGRCVN 507
Query: 1466 T-------CNPVYE-----KYCADH---FADGRCDQGCNTEECGWDGLDCASEVPALLAR 1510
T CN +E K C DH C G E G C + LLA
Sbjct: 508 TEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDG--SFSCLCKPGFLLAP 565
Query: 1511 G 1511
G
Sbjct: 566 G 566
Score = 45.1 bits (105), Expect = 8e-04
Identities = 44/163 (26%), Positives = 55/163 (33%), Gaps = 47/163 (28%)
Query: 1270 GLTFTCHCAQPFWGP---RCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRS 1326
G F +C P W R + V CR C G Q C C G PSC
Sbjct: 61 GSRFHAYCC-PGWRTFPGRSQCVVPICRRA-CGEGFCSQPN----LCTCADGTLAPSC-- 112
Query: 1327 FPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPR 1386
G S S + C++GG+CR A C C +G+TG C P
Sbjct: 113 ------GVSRGSGCSVSCMNGGTCRGAS------CLCQKGYTGTVCGQPI---------- 150
Query: 1387 CPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCE 1429
CDR C++ G C+ G QCE
Sbjct: 151 --------------CDRGCHNGGRCIGPNRCACVYGFMGPQCE 179
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 446 bits (1147), Expect = e-124
Identities = 443/1524 (29%), Positives = 603/1524 (39%), Gaps = 286/1524 (18%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCAGRGVCQSSVV 98
C D +GG+CT +P E CLC G++ C + C P +C S
Sbjct: 1242 CEDNPNICDGGQCTNIPG-EYRCLCYDGFMASEDMKTCVDVNECDLNP----NICLSGTC 1296
Query: 99 AGT-ARFSCRCPRGFRGPD----CSLPDPCL--SSPCAHGARCSVGPDGRFLCSCPPGYQ 151
T F C C G+ G C+ + C + C A C+ G F CSC PG+
Sbjct: 1297 ENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCT-NTAGSFKCSCSPGWI 1355
Query: 152 GRSCR-SDVDECRVG-EPCRHGGTCLNTPGSFRCQCPAGYTGP--LCENPAVPCAPSP-- 205
G + +D+DEC G C C NT GS+RC C GYTG C + C+ +
Sbjct: 1356 GDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTD-LDECSENLNL 1414
Query: 206 CRNGGTCRQSGDLTYDCACLPGF----EGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 261
C NG G Y C C GF +G+ CE ++D+C GTC + + C+
Sbjct: 1415 CGNGQCLNAPGG--YRCECDMGFVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCE 1471
Query: 262 CPPEW----TGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDD 317
C + +G CT DV+EC L P C +G C NT G + C C + D
Sbjct: 1472 CEIGYELDRSGGNCT-DVNEC-LDPTTCISGN-CVNTPGSYICDCPPDFELNPTRVGCVD 1528
Query: 318 CATAVCF--------HGAT-CHDR----VASFYCACPMGKTG----------------LL 348
+ C+ +G T C + V+ C C +GK +L
Sbjct: 1529 TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKIL 1588
Query: 349 CHLDDACVSNP----------CHE-DAICDTNP-VN--GRAICTCPPGF----TGGACDQ 390
C + NP C E +C +N G C CP G+ CD
Sbjct: 1589 CPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCD- 1647
Query: 391 DVDECSIGA--NPCEHLGRCVNTQGSFLCQCGRGYT----GPRC---------------- 428
DV+EC P G C NT G++ C C Y G C
Sbjct: 1648 DVNECETPGICGP----GTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADN 1703
Query: 429 ETDVNECLSGPCRNQATCLDRIG----------------QFTCICMAGFTG------TYC 466
+T E L + C IG +F +C + G T
Sbjct: 1704 QTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL 1763
Query: 467 EVDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFSGSTCQL---DVDECASTP-CRNGAK 521
VDIDEC+ P V GVC + V F C CP GF + L D+DEC + P C+ A+
Sbjct: 1764 PVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAE 1823
Query: 522 CVDQPDGYECRCAEGFE----GTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGT 577
C++ Y C C G+ G DRN P+ C HG+C+D + SF C C G+
Sbjct: 1824 CINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 578 RCESQ---VDECRSQPCRHGGKCLDLVDKYLCRCPSG--TTGVNCEVNIDDCAS---NPC 629
++ ++EC C +G C + + + CRC G + N +++D+CAS N C
Sbjct: 1884 DDQTMCLDINECERDACGNG-TCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLC 1942
Query: 630 TFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSP--CGEGGSCVDGENGFRCLC 683
G C + + + C C G+ G C V+INEC P C G +C + + +RC+C
Sbjct: 1943 RNGQCINTVGSFQCQCNEGYEVAPDGRTC-VDINECLLEPRKCAPG-TCQNLDGSYRCIC 2000
Query: 684 PPG-SLPPLCLPPSHPCAHEP--CSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARD 736
PPG SL C EP C+ G C + G F+C+C G+S G RC Q L
Sbjct: 2001 PPGYSLQNEKCEDIDECVEEPEICALGTCSNTEGSFKCLCPEGFSLSSSGRRC-QDLRMS 2059
Query: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
C ++ GG CSS H Q C L +PCE C + P +
Sbjct: 2060 YCYAK--FEGGKCSSPKSRNHSK-----QECCCALKGEGWGDPCE---LCPTEPDEAFRQ 2109
Query: 797 SCPQGWQ---GPRCQQ-DVDECAGPAPCGPHGICTNLAGSFSCTCHGGY--TGPSCDQDI 850
CP G GP D+DEC P C HG C N GS+ C C GY G C D
Sbjct: 2110 ICPYGSGIIVGPDDSAVDMDECKEPDVC-KHGQCINTDGSYRCECPFGYILAGNEC-VDT 2167
Query: 851 NDCDP-NPCLNGGSCQDGVGSFSCSCLPGFA-GPRCA-RDVDECLSNP--CGPGTCTDHV 905
++C NPC NG +C++ +G F C+C GF GP D++EC NP C C +
Sbjct: 2168 DECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCA-FRCVNTY 2225
Query: 906 ASFTCTCPPGY----------GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYT 955
S+ C CP GY CE+ DC+ C + + ++ C+C PGY
Sbjct: 2226 GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQM----ECKNLIGTYMCICGPGYQ 2281
Query: 956 ----GAHCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ 1010
G C E + C ++P + G C + C C + FT Q D C
Sbjct: 2282 RRPDGEGCVDENE-CQTKPGICENGRCLNTRGSYTCECNDGFTASPNQ---DECLDN--- 2334
Query: 1011 NGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC 1070
G C +C G S R +S C + G E +C G +
Sbjct: 2335 REGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCE-ICPFQGTVAFKK----- 2388
Query: 1071 VCPEGRTGSHCEQEVDPC--LAQPCQHGGTCRGYMGGYMCECLPGYN----GDNCEDDVD 1124
+CP GR ++D C + C++G C G Y C C GY G +C D ++
Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVCRNG-ECVNDRGSYHCICKTGYTPDITGTSCVD-LN 2446
Query: 1125 ECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT--C 1182
EC P C + Y CSCP G I ++D LD HN C
Sbjct: 2447 ECNQAPKPCNFICKNTEGSYQCSCPKGY------ILQEDGRSCKDLDECATKQHNCQFLC 2500
Query: 1183 VDLVGGFRCTCPPGYT--------GLRCEADINECRS-GACHAAHTRDCLQDPGGGFRCL 1233
V+ +GGF C CPPG+T C +DIN C S G C Q+ G F C
Sbjct: 2501 VNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGIC---------QNTPGSFTCE 2551
Query: 1234 CHAGFS----GPRCQTVLSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHCAQPF-----WG 1283
C GFS G C+ V CE + CQHG C+ G + C C Q + W
Sbjct: 2552 CQRGFSLDQTGSSCEDV-DECEGNHRCQHG--CQNIIG-----GYRCSCPQGYLQHYQWN 2603
Query: 1284 PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAP 1343
+ C G C T +C CP G F G + A AP
Sbjct: 2604 QCVDE--NECLSAHICGGASCHNTLGSYKCMCPAGF---QYEQFSGGCQDINECGSAQAP 2658
Query: 1344 CLHGGSCRPAPLAPFFRCACAQGW 1367
C +G S + C C G+
Sbjct: 2659 CSYGCSNTEGG----YLCGCPPGY 2678
Score = 413 bits (1061), Expect = e-114
Identities = 433/1671 (25%), Positives = 626/1671 (37%), Gaps = 381/1671 (22%)
Query: 49 CANGGRCTQLPSREAACLCPPGWV----GERC---QLEDPCHSGPCAGRGVCQSSVVAGT 101
C NG RC C C PG G C + C+ G RG C +
Sbjct: 623 CMNG-RCVNTDG-SYRCECFPGLAVGLDGRVCVDTHMRSTCYGG--YKRGQCIKPLFGAV 678
Query: 102 ARFSCRCPRGFRGPDCSLPDPCLSSPCAHGAR--------------------CSVGPD-- 139
+ C C + + +PC P + A C++ PD
Sbjct: 679 TKSECCCA----STEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDIC 734
Query: 140 ---------GRFLCSCPPGYQ----GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCP 186
G + C C GY+ G++C D++EC + G C NTPGSF C CP
Sbjct: 735 PNGICENLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCP 793
Query: 187 AGYTG----PLCENPAVPCAPSPCRNGGTCRQSGDLTYDCA-----------CLPGFEGQ 231
G+ CE+ C SPC NG G +C+ C+ +G
Sbjct: 794 KGFIYKPDLKTCED-IDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGT 852
Query: 232 --------NCEVNVDDCP-GHRCLNGGTCVDGVNTYNCQCPP-------EWTGQFCTEDV 275
CE+N++ +C + G CQ P G C ED+
Sbjct: 853 CWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQC-EDI 911
Query: 276 DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335
DEC++ P C N G C NT G C C +G T ++ + D CF D +
Sbjct: 912 DECEVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF--LRYEDEECT 968
Query: 336 FYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGF------TGGACD 389
A C + A + C E + N +C PGF G
Sbjct: 969 LPIAGRHRMDACCCSVGAAWGTEECEECPM--RNTPEYEELCPRGPGFATKEITNGKPFF 1026
Query: 390 QDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY---TGPRCETDVNEC-LSGPCRNQAT 445
+D++EC + + C H G+C NT GSF C+C G+ + R TD++EC +S +
Sbjct: 1027 KDINECKMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ 1085
Query: 446 CLDRIGQFTCICMAGFTGTYCE----VDIDECQSSPCV-NGGVCKDRVNGFSCTCPSGFS 500
C++ G F C C G+ + +DIDECQ P + GGVC + + C CP G
Sbjct: 1086 CVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ 1145
Query: 501 GS---TCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFEGT---LCDRNVDDCS-P 551
S + +D++EC ++ C NG +CV+ Y+C C G+ T L ++D+CS
Sbjct: 1146 LSPNISACIDINECELSAHLCPNG-RCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIM 1204
Query: 552 DPCHHGRCVDGIASFSCACAPGYT---GTRCESQVDECRSQP-CRHGGKCLDLVDKYLCR 607
+ C + S+ C+C PG+ R + +DEC P GG+C ++ +Y C
Sbjct: 1205 NGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCL 1264
Query: 608 CPSG---TTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGFTGPLCN---VEIN 659
C G + + V++++C NP C G C + + C C G++G +IN
Sbjct: 1265 CYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDIN 1324
Query: 660 EC--ASSPCGEGGSCVDGENGFRCLCPPGSLP--------PLCLPPSHPCAHEPCSHGIC 709
EC + CG+ C + F+C C PG + C +H C+ H C
Sbjct: 1325 ECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCS----QHADC 1380
Query: 710 YDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCP----PGVQ 765
+ G +RC+C+ G++G + + + E+ G C + G+ C C P
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD 1440
Query: 766 GRQCELLSPCT-PNPCEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECAGPAPC 820
G+ CE + C+ PN C G C + PG L C C G++ G C DV+EC P C
Sbjct: 1441 GKACEDIDECSLPNICVF-GTCHNLPG-LFRCECEIGYELDRSGGNC-TDVNECLDPTTC 1497
Query: 821 GPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC--DPNPCLNGG--SCQD----G 867
G C N GS+ C C + T C D +C D P + G +C + G
Sbjct: 1498 -ISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVG 1556
Query: 868 VGSFSCSC------------------------LPGFAGPR------CARDVDECLSNP-- 895
V SC C PG G R D+DEC P
Sbjct: 1557 VSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGL 1616
Query: 896 CGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP 952
C G C + SF C CP GY D+ +C GTC + V +++C+C P
Sbjct: 1617 CQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPP 1676
Query: 953 GYTGAH--------------------------------------CQHEADPCLSRPCLH- 973
Y + C + ++PC
Sbjct: 1677 DYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQC 1736
Query: 974 --------GGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQP--CQNGGRCVQTGAY-C 1022
+C + PGF ++ +TG +D C P C+NG G++ C
Sbjct: 1737 PIPSTDEFATLCGSQRPGF---VIDIYTGLPVD--IDECREIPGVCENGVCINMVGSFRC 1791
Query: 1023 LCPPGW----------------SGRLCDIRSLPCREAAAQI------GVRLEQL------ 1054
CP G+ +G +C R+ C A G R
Sbjct: 1792 ECPVGFFYNDKLLVCEDIDECQNGPVCQ-RNAECINTAGSYRCDCKPGYRFTSTGQCNDR 1850
Query: 1055 --CQ------AGGQCVDEDSSHYCVCPEGRTGSHCEQ---EVDPCLAQPCQHGGTCRGYM 1103
CQ + GQC+D S YC+C G + + +++ C C + GTCR +
Sbjct: 1851 NECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGN-GTCRNTI 1909
Query: 1104 GGYMCECLPGYNGDNCED--DVDECAS---QPCQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
G + C C G+ + D DVDECAS C++ G CI+ V + C C G E
Sbjct: 1910 GSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNEG-----YE 1963
Query: 1159 INED--DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT--GLRCEADINE------ 1208
+ D C PR GTC +L G +RC CPPGY+ +CE DI+E
Sbjct: 1964 VAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPE 2022
Query: 1209 -CRSGACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRCQTV-LSPCESQPCQHGGQCR 1262
C G C + G F+CLC GF SG RCQ + +S C ++ GG+C
Sbjct: 2023 ICALGTC---------SNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAK--FEGGKC- 2070
Query: 1263 PSPGPGGGLTFTCHCA--QPFWGPRCERVARSCREL---QCPVGV--------------- 1302
SP C CA WG CE E CP G
Sbjct: 2071 SSPKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDE 2130
Query: 1303 ----------PCQQTPRGPRCACPPG--LSGPSCRSFPGSPPGASNASCAAAPCLHGGSC 1350
C T RC CP G L+G C C+ G+C
Sbjct: 2131 CKEPDVCKHGQCINTDGSYRCECPFGYILAGNEC---------VDTDECSVGNPCGNGTC 2181
Query: 1351 RPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRC 1401
+ + F C C +G+ E ++ P C G C
Sbjct: 2182 K--NVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFRCVNTYGSYEC 2230
Score = 396 bits (1017), Expect = e-109
Identities = 473/1761 (26%), Positives = 665/1761 (37%), Gaps = 376/1761 (21%)
Query: 14 PMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVG 73
P P PPPP+ +P +L + PG P + P PSRE + P V
Sbjct: 396 PGRPEYPPPPLGPIPPVLPVP-PGFPPGPQI---PVPRPPVEYLYPSREPPRVLPVN-VT 450
Query: 74 ERCQL-EDPCHSGPCAGR-GVCQSSVVAGTARFSCRCPRGF----RGPDCSLPDPCLSSP 127
+ CQL C +G C G C+ C C +GF RG +C D C +P
Sbjct: 451 DYCQLVRYLCQNGRCIPTPGSCR-----------CECNKGFQLDLRG-ECIDVDECEKNP 498
Query: 128 CAHGARCSVGPDGRFLCSCPPGYQGRSCRS---DVDECRVGEPCRHGGTCLNTPGSFRCQ 184
CA G C + G + C C GYQ R+ D+DEC + G C+NT GSF C
Sbjct: 499 CA-GGEC-INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCV 556
Query: 185 CPAGY----TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGF----EGQNC-EV 235
C AG+ G CE+ + C NG + G ++ C C PGF +G+ C ++
Sbjct: 557 CNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDG--SFKCICKPGFQLASDGRYCKDI 614
Query: 236 NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWT----GQFCTEDVDECQLQPNACHNG--- 288
N + PG C+N G CV+ +Y C+C P G+ C + + C+ G
Sbjct: 615 NECETPG-ICMN-GRCVNTDGSYRCECFPGLAVGLDGRVCVD-----THMRSTCYGGYKR 667
Query: 289 GTCFNTLGG------------------------------HSCVCVNGWTGESCSQNIDDC 318
G C L G + +C +G S +I++C
Sbjct: 668 GQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINEC 727
Query: 319 A--TAVCFHGATCHDRVASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVN 372
A +C +G C + ++ C C G TG C + CV N +CD
Sbjct: 728 ALDPDICPNG-ICENLRGTYKCICNSGYEVDSTGKNCVDINECVLN----SLLCDNGQCR 782
Query: 373 ---GRAICTCPPGFTG----GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTG 425
G +CTCP GF C +D+DEC ++PC + G C N+ GSF+C+C T
Sbjct: 783 NTPGSFVCTCPKGFIYKPDLKTC-EDIDECE--SSPCIN-GVCKNSPGSFICECSSESTL 838
Query: 426 PRCETDVNECLSGPC------------RNQAT----CLDRIG----------QFTCICMA 459
+T E + G C N AT C +G Q IC
Sbjct: 839 DPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGK 898
Query: 460 GFT---GTYCEVDIDECQSSPCV-NGGVCKDRVNGFSCTCPSG----------------- 498
G++ GT CE DIDEC+ P V G+C + F C CPSG
Sbjct: 899 GYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLET 957
Query: 499 ----FSGSTCQLDV-------------------DECASTPCRNGAKCVDQ-PDGYECRCA 534
+ C L + +EC P RN + + P G
Sbjct: 958 CFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATK 1017
Query: 535 EGFEGTLCDRNVDDCS--PDPCHHGRCVDGIASFSCACAPGY---TGTRCESQVDECRSQ 589
E G +++++C P C HG+C + I SF C C G+ + R + +DECR
Sbjct: 1018 EITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRIS 1077
Query: 590 PCRHG-GKCLDLVDKYLCRCPSGTTG-----VNCEVNIDDCASNP--CTFGVCRDGINRY 641
P G G+C++ + C+C G NC ++ID+C +P C GVC + Y
Sbjct: 1078 PDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLLCRGGVCHNTEGSY 1136
Query: 642 DCVCQPGF-TGPLCN--VEINEC-ASSPCGEGGSCVDGENGFRCLCPPG--SLPP--LCL 693
C C PG P + ++INEC S+ G CV+ ++C C PG S P C+
Sbjct: 1137 RCECPPGHQLSPNISACIDINECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCV 1196
Query: 694 PPSHPCAHEPCSHGICYDAPGGFRCVCEPGWS-GPRCSQSLARDACESQP-CRAGGTCSS 751
C ++ G + C C+PG++ P D CE P GG C++
Sbjct: 1197 DIDECSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTN 1256
Query: 752 DGMGFHCTCPPGVQG----RQCELLSPC--TPNPCEHGGRCESAPGQLPVCSCPQGWQGP 805
+ C C G + C ++ C PN C G CE+ G +C C G+ G
Sbjct: 1257 IPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNIC-LSGTCENTKGSF-ICHCDMGYSGK 1314
Query: 806 RCQ---QDVDEC-AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD-QDINDCD--PNPC 858
+ + D++EC G CG H +CTN AGSF C+C G+ G D+++C + C
Sbjct: 1315 KGKTGCTDINECEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMC 1374
Query: 859 LNGGSCQDGVGSFSCSCLPGFAGPR-CARDVDECLS--NPCGPGTCTDHVASFTCTCPPG 915
C++ +GS+ C C G+ G D+DEC N CG G C + + C C G
Sbjct: 1375 SQHADCKNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMG 1434
Query: 916 Y----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQHEADPCL 967
+ G CE D+ +CS + GTC + F C C GY +G +C + + CL
Sbjct: 1435 FVPSADGKACE-DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCT-DVNECL 1492
Query: 968 SRPCLHGGVCSAAHPGFRCTCLESF-TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPP 1026
G C + C C F P VD G C + P
Sbjct: 1493 DPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD-------TRSGNCYLD----IRPR 1541
Query: 1027 GWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQ--------CVDEDSSHYCVCPEGRTG 1078
G +G C +GV C + G+ C ++S Y + G G
Sbjct: 1542 GDNG------DTACSNEIG-VGVSKASCCCSLGKAWGTPCEMCPAVNTSEYKILCPGGEG 1594
Query: 1079 SHCE------QEVDPCLAQP--CQHGGTCRGYMGGYMCECLPGY--NGDN--CEDDVDEC 1126
+++D C P CQ GG C G + C C GY N D C DDV+EC
Sbjct: 1595 FRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSFQCRCPTGYYLNEDTRVC-DDVNEC 1652
Query: 1127 ASQPCQHGGSCIDLVARYLCSCPPGTLGV------------LCEIN---EDDCGPGPPLD 1171
+ G+C + V Y C CPP + V LC N ++ G L
Sbjct: 1653 ETPGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLF 1712
Query: 1172 SGPR----CLH------NGTC----VDLVGGFRCTC---PPG-----YTGLRCEADINEC 1209
+ + C + N C + F C PG YTGL DI+EC
Sbjct: 1713 NMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGL--PVDIDEC 1770
Query: 1210 RS--GACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTV---LSPCESQP-CQHGGQCRP 1263
R G C + + G FRC C GF V + C++ P CQ +C
Sbjct: 1771 REIPGVCENGVCINMV----GSFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECIN 1826
Query: 1264 SPG-------PGGGLTFTCHCAQPFWGPRCERVARSCRELQC--PVG------------- 1301
+ G PG T T C C+ + C QC VG
Sbjct: 1827 TAGSYRCDCKPGYRFTSTGQCND---RNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTN 1883
Query: 1302 ---VPCQQTPRGPRCACPPG-----LSGPSCRSFPGSPPGASNASCAAAPCL--HGGSCR 1351
C R AC G + +CR G +N C +G CR
Sbjct: 1884 DDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCR 1943
Query: 1352 PAP---LAPFFRCACAQGW-TGPRCEAPAAAPEVSEEPR-CPRAACQAKRGDQRCDRECN 1406
F+C C +G+ P E EPR C CQ G RC
Sbjct: 1944 NGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAPGTCQNLDGSYRC---IC 2000
Query: 1407 SPGCGWDGGDC---SLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR 1463
PG C V +P C C +N+ C P + F + GR
Sbjct: 2001 PPGYSLQNEKCEDIDECVEEP-EICALGTC----SNTEGSFKCLCP----EGFSLSSSGR 2051
Query: 1464 ERTCNPVYEKYCADHFADGRC 1484
C + YC F G+C
Sbjct: 2052 R--CQDLRMSYCYAKFEGGKC 2070
Score = 378 bits (970), Expect = e-104
Identities = 465/1728 (26%), Positives = 653/1728 (37%), Gaps = 387/1728 (22%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGE----RCQLEDPCHSGPCAGRGVCQSS-- 96
C+ S + G+C P C CP G++ + C+ D C S PC GVC++S
Sbjct: 769 CVLNSLLCDNGQCRNTPG-SFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSPG 826
Query: 97 -----------------VVAGTARFSC-------RCPRGFRGPD-----CSLPDPCLSSP 127
+ T + +C RC G CS SP
Sbjct: 827 SFICECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSP 886
Query: 128 CAHGARCSVGPDGRFLCSCPPGY---QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQ 184
C C V P C GY +G C D+DEC V G C+NT GSF+CQ
Sbjct: 887 CT---LCQVDP------ICGKGYSRIKGTQCE-DIDECEVFPGVCKNGLCVNTRGSFKCQ 936
Query: 185 CPAGY----TGPLC--------------ENPAVP---------CAPSPCRNGGT-----C 212
CP+G TG +C E +P C S GT C
Sbjct: 937 CPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEEC 996
Query: 213 RQSGDLTYD--CACLPGF------EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCP 263
Y+ C PGF G+ ++++C L G C + + ++ C+C
Sbjct: 997 PMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCD 1056
Query: 264 PEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTG-----ESCSQN 314
+ + CT D+DEC++ P+ C G C NT G C C G+ ++C +
Sbjct: 1057 SGFALDSEERNCT-DIDECRISPDLC-GRGQCVNTPGDFECKCDEGYESGFMMMKNC-MD 1113
Query: 315 IDDC-ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS-NPCHEDA-ICDTNPV 371
ID+C + G CH+ S+ C CP G L AC+ N C A +C
Sbjct: 1114 IDECQRDPLLCRGGVCHNTEGSYRCECPPGHQ--LSPNISACIDINECELSAHLCP---- 1167
Query: 372 NGRAI-------CTCPPGFTGGA----CDQDVDECSIGANPCEHLGRCVNTQGSFLCQCG 420
NGR + C C PG+ C D+DECSI CE C N++GS+ C C
Sbjct: 1168 NGRCVNLIGKYQCACNPGYHSTPDRLFC-VDIDECSIMNGGCETF--CTNSEGSYECSCQ 1224
Query: 421 RGYT---GPRCETDVNECLSGP-CRNQATCLDRIGQFTCICMAGFTGT----YCEVDIDE 472
G+ R TD++EC P + C + G++ C+C GF + C VD++E
Sbjct: 1225 PGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTC-VDVNE 1283
Query: 473 CQSSP--CVNGGVCKDRVNGFSCTCPSGFS---GSTCQLDVDEC--ASTPCRNGAKCVDQ 525
C +P C++ G C++ F C C G+S G T D++EC + C A C +
Sbjct: 1284 CDLNPNICLS-GTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAVCTNT 1342
Query: 526 PDGYECRCAEGF--EGTLCDRNVDDCSPDP---CHHGRCVDGIASFSCACAPGYTGT--R 578
++C C+ G+ +G C ++D+CS H C + + S+ C C GYTG
Sbjct: 1343 AGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFT 1401
Query: 579 CESQVDECRSQPCRHG-GKCLDLVDKYLCRCPSG----TTGVNCEVNIDDCA-SNPCTFG 632
C + +DEC G G+CL+ Y C C G G CE +ID+C+ N C FG
Sbjct: 1402 C-TDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACE-DIDECSLPNICVFG 1459
Query: 633 VCRDGINRYDCVCQPGF----TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSL 688
C + + C C+ G+ +G C ++NEC G+CV+ + C CP
Sbjct: 1460 TCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVNTPGSYICDCP---- 1514
Query: 689 PPLCLPPSHPCAHEPCSHGICY------DAPGGFRCVCEPGWSGPRCSQSLARDACESQP 742
P L P+ + S G CY G C E G + S + P
Sbjct: 1515 PDFELNPTRVGCVDTRS-GNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTP 1573
Query: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQ-------CELLSPC--TPNPCEHGGRCESAPGQL 793
C ++ C PG +G + E + C P C+ GG+C + G
Sbjct: 1574 CEMCPAVNTSEYKILC---PGGEGFRPNPITVILEDIDECQELPGLCQ-GGKCINTFGSF 1629
Query: 794 PVCSCPQGW---QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSC 846
C CP G+ + R DV+EC P CGP G C N G+++C C Y G +C
Sbjct: 1630 Q-CRCPTGYYLNEDTRVCDDVNECETPGICGP-GTCYNTVGNYTCICPPDYMQVNGGNNC 1687
Query: 847 -DQDINDCDPNPCLNGGSCQDGVGSFS-----CSC------------------------- 875
D + C N + +C DG F+ C C
Sbjct: 1688 MDMRRSLCYRNYYADNQTC-DGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEFAT 1746
Query: 876 -----LPGFA---GPRCARDVDECLSNP--CGPGTCTDHVASFTCTCPPGYGGFHCE--- 922
PGF D+DEC P C G C + V SF C CP G+ F+ +
Sbjct: 1747 LCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGF--FYNDKLL 1804
Query: 923 --QDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGY--TGAHCQHEADPCLSRP--CLHGG 975
+D+ +C C C++ S+ C C+PGY T ++ + C P C H G
Sbjct: 1805 VCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNICSH-G 1863
Query: 976 VCSAAHPGFRCTCLESFTGPQCQTL---VDWCSRQPCQNGGRCVQTGAY-CLCPPGW--- 1028
C F C C F QT+ ++ C R C NG G++ C C G+
Sbjct: 1864 QCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGFILS 1923
Query: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQE 1084
C + E A+ G LC+ GQC++ S C C EG G C +
Sbjct: 1924 HNNDC----IDVDECASGNG----NLCR-NGQCINTVGSFQCQCNEGYEVAPDGRTC-VD 1973
Query: 1085 VDPCLAQPCQHG-GTCRGYMGGYMCECLPGYN--GDNCEDDVDECASQP--CQHGGSCID 1139
++ CL +P + GTC+ G Y C C PGY+ + CE D+DEC +P C G+C +
Sbjct: 1974 INECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICAL-GTCSN 2031
Query: 1140 LVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC--LHNGTCVDLVGGFRCTCPPGY 1197
+ C CP G SG RC L C G +C+ P
Sbjct: 2032 TEGSFKCLCPEGF---------------SLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSR 2076
Query: 1198 TGLR---CEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAG---FSGPRCQTV-LSPC 1250
+ C A E C C +P FR +C G GP V + C
Sbjct: 2077 NHSKQECCCALKGEGWGDPCEL-----CPTEPDEAFRQICPYGSGIIVGPDDSAVDMDEC 2131
Query: 1251 -ESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW----GPRCERVARSCRELQCPVGVPCQ 1305
E C+H GQC + G ++ C C PF G C +C VG PC
Sbjct: 2132 KEPDVCKH-GQCINTDG-----SYRCEC--PFGYILAGNECVDTD------ECSVGNPCG 2177
Query: 1306 QTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQ 1365
C + G C G PG C C PL FRC
Sbjct: 2178 NG------TCKNVIGGFECTCEEGFEPG------PMMTCEDINECAQNPLLCAFRCVNTY 2225
Query: 1366 GWTGPRCEAPAAAPE----VSEEPRC---------PRAACQAKRGDQRC------DRECN 1406
G +C E +E C + C+ G C R +
Sbjct: 2226 GSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPD 2285
Query: 1407 SPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRC---DPACSSP---ACLYDNFD--- 1457
GC D +C G CE +C + C D +SP CL DN +
Sbjct: 2286 GEGC-VDENECQTKPG----ICENGRCLNTRGSYTCECNDGFTASPNQDECL-DNREGYC 2339
Query: 1458 --------CHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDG 1497
C G R NPV + C DG G + E C + G
Sbjct: 2340 FTEVLQNMCQIGSSNR--NPVTKSECC---CDGGRGWGPHCEICPFQG 2382
Score = 375 bits (964), Expect = e-103
Identities = 427/1600 (26%), Positives = 587/1600 (36%), Gaps = 358/1600 (22%)
Query: 60 SREAACLCPPGWVGERCQLEDPCHSG-PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 118
SR C CP G + C H C G C C C +G+ G C
Sbjct: 95 SRPNMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD--------HCLCQKGYIGTHCG 146
Query: 119 LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC---------- 168
P S C +G RC V P+ C+C G+ G C D R G PC
Sbjct: 147 --QPVCESGCLNGGRC-VAPN---RCACTYGFTGPQCERDY---RTG-PCFTVISNQMCQ 196
Query: 169 --RHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226
G C T C G CE P P PCR G +P
Sbjct: 197 GQLSGIVCTKT---LCCATVGRAWGHPCE--MCPAQPHPCRRG--------------FIP 237
Query: 227 GFEGQNCEVNVDDC---PGHRCLNGGTCVDGVNTYNCQCPP----EWTGQFCTEDVDECQ 279
C+ +VD+C PG GG C++ V ++ C+CP Q C ED+DEC
Sbjct: 238 NIRTGACQ-DVDECQAIPG--LCQGGNCINTVGSFECKCPAGHKLNEVSQKC-EDIDECS 293
Query: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT---CHDR---- 332
P C GG C NT+ + C C G+ D C+ T C ++
Sbjct: 294 TIPGIC-EGGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQS 352
Query: 333 VASFYCACPMGKTGLLCHLDDACVS-NPCHEDAICDTNP-------VNGR---------- 374
+ C C G+ C V+ C A D N + GR
Sbjct: 353 ITKMQCCCDAGR----CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGP 408
Query: 375 --AICTCPPGFTGG----------------------ACDQDVDECSIGANPCEHLGRCVN 410
+ PPGF G D C + C++ GRC+
Sbjct: 409 IPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQN-GRCIP 467
Query: 411 TQGSFLCQCGRGY---TGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF----TG 463
T GS C+C +G+ C DV+EC PC C++ G +TC C AG+ T
Sbjct: 468 TPGSCRCECNKGFQLDLRGEC-IDVDECEKNPCAG-GECINNQGSYTCQCRAGYQSTLTR 525
Query: 464 TYCEVDIDEC-QSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECA-STPCR 517
T C DIDEC Q+ N G C + F C C +GF G C+ D+DEC+ C
Sbjct: 526 TECR-DIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCL 583
Query: 518 NGAKCVDQPDGYECRCAEGF----EGTLCDRNVDDC-SPDPCHHGRCVDGIASFSCACAP 572
NG C+++ ++C C GF +G C +++++C +P C +GRCV+ S+ C C P
Sbjct: 584 NG-MCINEDGSFKCICKPGFQLASDGRYC-KDINECETPGICMNGRCVNTDGSYRCECFP 641
Query: 573 GY-TGTRCESQVDECRSQPCRHG---GKCLDLV--------------------------- 601
G G VD C G G+C+ +
Sbjct: 642 GLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPA 701
Query: 602 ---DKYLCRCPSGTTGVNCEVNIDDCASNP--CTFGVCRDGINRYDCVCQPGF----TGP 652
+Y C SG + +I++CA +P C G+C + Y C+C G+ TG
Sbjct: 702 QNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGK 761
Query: 653 LCNVEINECA-SSPCGEGGSCVDGENGFRCLCPPGSL--PPL-CLPPSHPCAHEPCSHGI 708
C V+INEC +S + G C + F C CP G + P L C PC +G+
Sbjct: 762 NC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCINGV 820
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRA-GGTCSSDGMGFHCTC---PPGV 764
C ++PG F C CS D ++ GTC + C +
Sbjct: 821 CKNSPGSFIC---------ECSSESTLDPTKTICIETIKGTCWQTVIDGRCEININGATL 871
Query: 765 QGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGW---QGPRCQQDVDEC-AGPAPC 820
+ + C L +PC C+ P C +G+ +G +C +D+DEC P C
Sbjct: 872 KSQCCSSLGAAWGSPCT---LCQVDP------ICGKGYSRIKGTQC-EDIDECEVFPGVC 921
Query: 821 GPHGICTNLAGSFSCTCHGGY----TGPSC-DQDINDC----DPNPC---------LNGG 862
+G+C N GSF C C G TG C D + C + C ++
Sbjct: 922 -KNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMDAC 980
Query: 863 SCQDGVGSFSCSCL-----------------PGFA------GPRCARDVDECLSNP--CG 897
C G + C PGFA G +D++EC P C
Sbjct: 981 CCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCT 1040
Query: 898 PGTCTDHVASFTCTCPPGYGGFHCEQ---DLPDC--SPSSCFNGGTCVDGVNSFSCLCRP 952
G C + + SF C C G+ E+ D+ +C SP C G CV+ F C C
Sbjct: 1041 HGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLC-GRGQCVNTPGDFECKCDE 1099
Query: 953 GYTGA-----HCQHEADPCLSRPCL-HGGVCSAAHPGFRCTCLESF-TGPQCQTLVD--- 1002
GY +C + D C P L GGVC +RC C P +D
Sbjct: 1100 GYESGFMMMKNCM-DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDINE 1158
Query: 1003 -WCSRQPCQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
S C N GRCV G Y C C PG+ S P R I E GG
Sbjct: 1159 CELSAHLCPN-GRCVNLIGKYQCACNPGY-------HSTPDRLFCVDID---ECSIMNGG 1207
Query: 1060 ---QCVDEDSSHYCVCPEG---RTGSHCEQEVDPCLAQP--CQHGGTCRGYMGGYMCECL 1111
C + + S+ C C G ++D C P C GG C G Y C C
Sbjct: 1208 CETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICD-GGQCTNIPGEYRCLCY 1266
Query: 1112 PGYNGDNCED-----DVDECASQP--CQHGGSCIDLVARYLCSCPPGTLGV-----LCEI 1159
G+ ED DV+EC P C G+C + ++C C G G +I
Sbjct: 1267 DGFMAS--EDMKTCVDVNECDLNPNICL-SGTCENTKGSFICHCDMGYSGKKGKTGCTDI 1323
Query: 1160 NEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY--TGLRCEADINECRSGACHAA 1217
NE + G C + C + G F+C+C PG+ G++C D++EC +G +
Sbjct: 1324 NECEIG-------AHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCS 1375
Query: 1218 HTRDCLQDPGGGFRCLCHAGFSGP--RCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC 1275
DC ++ G +RCLC G++G C + E+ GQC +PG + C
Sbjct: 1376 QHADC-KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPG-----GYRC 1429
Query: 1276 HCAQPFW----GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGL----SGPSCRSF 1327
C F G CE + C G C P RC C G SG +C
Sbjct: 1430 ECDMGFVPSADGKACEDIDECSLPNICVFGT-CHNLPGLFRCECEIGYELDRSGGNCTDV 1488
Query: 1328 PG--SPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEP 1385
P + +C P + C P R C +G C + P
Sbjct: 1489 NECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSG-NC-------YLDIRP 1540
Query: 1386 RCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPW 1425
R GD C E G G C S+G W
Sbjct: 1541 R-------GDNGDTACSNEI---GVGVSKASCCCSLGKAW 1570
Score = 249 bits (637), Expect = 2e-65
Identities = 346/1448 (23%), Positives = 487/1448 (33%), Gaps = 402/1448 (27%)
Query: 337 YCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC-DQDVDEC 395
YC CP KT + C+ C C + +CTCP G +C + + C
Sbjct: 66 YC-CPGWKT---LPGGNQCIVPICRHS--CGDGFCSRPNMCTCPSGQIAPSCGSRSIQHC 119
Query: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
+I C + G C + C C +GY G C V C SG C N C + C
Sbjct: 120 NIR---CMNGGSCSDDH----CLCQKGYIGTHCGQPV--CESG-CLNGGRC---VAPNRC 166
Query: 456 ICMAGFTGTYCEVDIDECQSSPC---VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECA 512
C GFTG CE D ++ PC ++ +C+ +++G CT + C V
Sbjct: 167 ACTYGFTGPQCERDY---RTGPCFTVISNQMCQGQLSGIVCT------KTLCCATVGRAW 217
Query: 513 STPCRNGAKCVDQPDGYECRCAEGFEGTL---CDRNVDDCSPDP--CHHGRCVDGIASFS 567
PC C QP C GF + ++VD+C P C G C++ + SF
Sbjct: 218 GHPCE---MCPAQPHP----CRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
Query: 568 CACAPGY----TGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSG----TTGVNC 617
C C G+ +CE +DEC + P C GG+C + V Y C+CP G G C
Sbjct: 271 CKCPAGHKLNEVSQKCED-IDECSTIPGICE-GGECTNTVSSYFCKCPPGFYTSPDGTRC 328
Query: 618 -EVNIDDCASNPCTFGVCRD----GINRYDCVC------QPGFT--------------GP 652
+V C + T G C + I + C C PG T
Sbjct: 329 IDVRPGYCYT-ALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNK 387
Query: 653 LCNVEI-----NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPP---SHPCAHEP- 703
LC+V + E P G + GF PPG P+ PP +P P
Sbjct: 388 LCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGF----PPGPQIPVPRPPVEYLYPSREPPR 443
Query: 704 ----------------CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG 747
C +G C PG RC C G+ + + D CE PC AGG
Sbjct: 444 VLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLDLRGECIDVDECEKNPC-AGG 502
Query: 748 TCSSDGMGFHCTCPPGVQG----RQCELLSPCTPNP--CEHGGRCESAPGQLPVCSCPQG 801
C ++ + C C G Q +C + C N C + GRC + G C C G
Sbjct: 503 ECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC-NNGRCINTDGSFH-CVCNAG 560
Query: 802 W----QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDC 853
+ G C +D+DEC+ C +G+C N GSF C C G+ G C +DIN+C
Sbjct: 561 FHVTRDGKNC-EDMDECSIRNMC-LNGMCINEDGSFKCICKPGFQLASDGRYC-KDINEC 617
Query: 854 D-PNPCLNGGSCQDGVGSFSCSCLPGFA-------------------------------- 880
+ P C+N G C + GS+ C C PG A
Sbjct: 618 ETPGICMN-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLFG 676
Query: 881 ----GPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCS--PSSCF 934
C + PC P + A + C G G D+ +C+ P C
Sbjct: 677 AVTKSECCCASTEYAFGEPCQP-CPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICP 735
Query: 935 NGGTCVDGVNSFSCLCRPGY----TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLE 990
N G C + ++ C+C GY TG +C + L+ G C F CTC +
Sbjct: 736 N-GICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQCRNTPGSFVCTCPK 794
Query: 991 SFT-GPQCQTL--VDWCSRQPCQNG-------------------------------GRCV 1016
F P +T +D C PC NG G C
Sbjct: 795 GFIYKPDLKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCW 854
Query: 1017 QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIG-----VRLEQLCQAG------------- 1058
QT C +G ++S C A G +++ +C G
Sbjct: 855 QTVIDGRCEINING--ATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDID 912
Query: 1059 -----------GQCVDEDSSHYCVCPEG----RTGSHC-EQEVDPCLA----QPCQHGGT 1098
G CV+ S C CP G TG C + ++ C + C
Sbjct: 913 ECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIA 972
Query: 1099 CRGYMGGYMCECLPGYNGDNCED--------------------------------DVDEC 1126
R M C + + CE+ D++EC
Sbjct: 973 GRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINEC 1032
Query: 1127 ASQP--CQHGGSCIDLVARYLCSCPPG----------TLGVLCEINEDDCGPG----PPL 1170
P C H G C + + + C C G T C I+ D CG G P
Sbjct: 1033 KMIPSLCTH-GKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPG 1091
Query: 1171 DSGPRC--------LHNGTCVDL------------------VGGFRCTCPPGY---TGLR 1201
D +C + C+D+ G +RC CPPG+ +
Sbjct: 1092 DFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNIS 1151
Query: 1202 CEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGP-----------------RCQ 1244
DINEC A H C+ + G ++C C+ G+ C+
Sbjct: 1152 ACIDINECELSA-HLCPNGRCV-NLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGCE 1209
Query: 1245 TVLS------PCESQP----------CQHGGQCRPSPG--PGGGLT-----FTCHCAQPF 1281
T + C QP C +C +P GG T + C C F
Sbjct: 1210 TFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGF 1269
Query: 1282 WGPRCERVARSCRELQCPVGV----PCQQTPRGPRCACPPGLSG----PSCRSFPGSPPG 1333
+ E + C+ T C C G SG C G
Sbjct: 1270 MASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGCTDINECEIG 1329
Query: 1334 ASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPR-AAC 1392
A N A GS F+C+C+ GW G + + C + A C
Sbjct: 1330 AHNCGKHAVCTNTAGS---------FKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC 1380
Query: 1393 QAKRGDQRCDRECNSPGCGW---DGGDCSLSVGDPWRQCEALQCWRLFNNSRCD------ 1443
+ G RC + G G+ D +CS ++ C QC RC+
Sbjct: 1381 KNTMGSYRCLCKEGYTGDGFTCTDLDECSENL----NLCGNGQCLNAPGGYRCECDMGFV 1436
Query: 1444 PACSSPAC 1451
P+ AC
Sbjct: 1437 PSADGKAC 1444
Score = 93.6 bits (231), Expect = 2e-18
Identities = 142/568 (25%), Positives = 191/568 (33%), Gaps = 147/568 (25%)
Query: 976 VCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
VC + + + C ++ G Q +V C R C +G C + C CP G C
Sbjct: 58 VCGSRYNAYCCPGWKTLPGGN-QCIVPIC-RHSCGDGF-CSRPNM-CTCPSGQIAPSCGS 113
Query: 1036 RSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQH 1095
RS+ +R C GG C D+ +C+C +G G+HC Q P C +
Sbjct: 114 RSIQ------HCNIR----CMNGGSCSDD----HCLCQKGYIGTHCGQ---PVCESGCLN 156
Query: 1096 GGTCRGYMGGYMCECLPGYNGDNCEDD--VDEC----ASQPCQHGGSCIDLVARYLCS-- 1147
GG C + C C G+ G CE D C ++Q CQ S I C+
Sbjct: 157 GGRC---VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATV 213
Query: 1148 ----------CP----PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC 1193
CP P G + I C + P G C++ VG F C C
Sbjct: 214 GRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKC 273
Query: 1194 PPGY----TGLRCEADINECRS--GACHAAHTRDCLQDPGGGFRCLCHAGF----SGPRC 1243
P G+ +CE DI+EC + G C + + + C C GF G RC
Sbjct: 274 PAGHKLNEVSQKCE-DIDECSTIPGICEGGECTNTV----SSYFCKCPPGFYTSPDGTRC 328
Query: 1244 QTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC-AQPFWGPRCERVARSC--------- 1293
V P G+C + P C C A W P C
Sbjct: 329 IDV-RPGYCYTALTNGRC-SNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFN 386
Query: 1294 RELQCPVGVPCQ-QTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP 1352
+ P+ +P + + P P PP L P PG PPG P
Sbjct: 387 KLCSVPMVIPGRPEYPPPPLGPIPPVLPVP-----PGFPPGPQ---------------IP 426
Query: 1353 APLAPFFRCACAQGWTGPRCEAPAAAP-EVSEEPRCPRAACQAKR-----GDQRCD---- 1402
P P + P E P P V++ + R CQ R G RC+
Sbjct: 427 VPRPPV-------EYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKG 479
Query: 1403 ------------RECNSPGCGWDGGDCSLSVGDPWRQC-----------------EALQC 1433
EC C GG+C + G QC E LQ
Sbjct: 480 FQLDLRGECIDVDECEKNPCA--GGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQN 537
Query: 1434 WRLFNNSRCDPACSSPACLYDNFDCHAG 1461
R+ NN RC S C+ C+AG
Sbjct: 538 GRICNNGRCINTDGSFHCV-----CNAG 560
Score = 80.5 bits (197), Expect = 2e-14
Identities = 100/364 (27%), Positives = 129/364 (35%), Gaps = 106/364 (29%)
Query: 141 RFLCSCPPGYQ----GRSCRSDVDECRVGEPCRHG---GTCLNTPGSFRCQCPAGYTGPL 193
R+ C PG++ G C + CRH G C + P C CP+G P
Sbjct: 62 RYNAYCCPGWKTLPGGNQCIVPI--------CRHSCGDGFC-SRPNM--CTCPSGQIAPS 110
Query: 194 CENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVD 253
C + ++ C NGG+C C C G+ G +C V + CLNGG C
Sbjct: 111 CGSRSIQHCNIRCMNGGSCSDD-----HCLCQKGYIGTHCGQPVCE---SGCLNGGRC-- 160
Query: 254 GVNTYNCQCPPEWTGQFCTEDV-----------DECQLQPNACHNGGT-CFNTLG---GH 298
V C C +TG C D CQ Q + T C T+G GH
Sbjct: 161 -VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGH 219
Query: 299 SC--------VCVNGWTGE---SCSQNIDDC-ATAVCFHGATCHDRVASFYCACPMGKTG 346
C C G+ Q++D+C A G C + V SF C CP G
Sbjct: 220 PCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGH-- 277
Query: 347 LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLG 406
L++ VS C + C T P G C+ G
Sbjct: 278 ---KLNE--VSQKCEDIDECSTIP---------------GICEG---------------G 302
Query: 407 RCVNTQGSFLCQCGRG-YTGP---RCETDV------NECLSGPCRNQATCLDRIGQFTCI 456
C NT S+ C+C G YT P RC DV +G C NQ I + C
Sbjct: 303 ECTNTVSSYFCKCPPGFYTSPDGTRC-IDVRPGYCYTALTNGRCSNQLP--QSITKMQCC 359
Query: 457 CMAG 460
C AG
Sbjct: 360 CDAG 363
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 443 bits (1139), Expect = e-123
Identities = 240/655 (36%), Positives = 318/655 (48%), Gaps = 64/655 (9%)
Query: 123 CLS-SPCAHGARC---SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTP 178
CL+ PC +G +C V + + CSC G+ GR C DV+EC +PC++GGTC +
Sbjct: 272 CLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC-ASQPCQNGGTCTHGI 330
Query: 179 GSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR-QSGDLTYDCACLPGFEGQNCEVNV 237
SFRCQCPAG+ GP CE PC C++GG C+ ++G C C G+ G CE++V
Sbjct: 331 NSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV--CVCQAGYTGAACEMDV 388
Query: 238 DDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC-TED---VDECQLQPNACHNGGTCFN 293
DDC CLNGG+CVD V Y C C + G C T D D C P CHNGGTC +
Sbjct: 389 DDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAP--CHNGGTCVD 446
Query: 294 TLGGHSCVCVNGWTGESCSQNI-DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD 352
G+ C C G+ G C + + DDC C +G C + C CP+G GLLC +
Sbjct: 447 ADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTL-CQCPLGFFGLLCEFE 502
Query: 353 DACVSNPCHEDAICDTNPV----NGRAICTCPPGFTG-----GACDQDVDECSIGANPCE 403
+ PC+ + C G +C C CD D PC
Sbjct: 503 --ITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSD---------PCF 551
Query: 404 HLGRCVNTQGSFLCQCGRGYTGPRCE-TDVNECLSGPCRNQATCLDRIGQFTCICMAGFT 462
+ G C S+ C+C RG+ G CE + C SGPCRN TC + G++ C C FT
Sbjct: 552 NGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFT 611
Query: 463 GTYCEV-DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAK 521
G +CE+ D C S PC NGG C + + C CP GFSG C++ C +PC NG
Sbjct: 612 GRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
Query: 522 CVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH------GRCVDGIASFSC------- 568
C D+ + C C G+ G C VD P+ H G + +A ++C
Sbjct: 672 CEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLS 731
Query: 569 ------ACAPGYTGTRCES--QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVN 620
C P + ++DECRSQPC HGG C D V YLC C +G G +CE+
Sbjct: 732 APSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE 791
Query: 621 IDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
D+C ++PC G CR+ Y C C GF G C E++ C SSPC GG C G +
Sbjct: 792 RDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAY 851
Query: 680 RCLCPPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSL 733
C+CP C S PC PC G C + G C C+ G++G C++ L
Sbjct: 852 LCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 438 bits (1127), Expect = e-122
Identities = 234/653 (35%), Positives = 316/653 (48%), Gaps = 54/653 (8%)
Query: 386 GACDQDVDECSIGANPCEHLGRCVNT----QGSFLCQCGRGYTGPRCETDVNECLSGPCR 441
G C C + PC + G+C++ S+ C C G+TG RC DVNEC S PC+
Sbjct: 263 GGCGHTTSVC-LALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQ 321
Query: 442 NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSG 501
N TC I F C C AGF G CE C + C +GG C+ C C +G++G
Sbjct: 322 NGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTG 381
Query: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRN----VDDCSPDPCHH- 556
+ C++DVD+C+ PC NG CVD Y C CAE F+G C+ D C PCH+
Sbjct: 382 AACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNG 441
Query: 557 GRCVDGIASFSCACAPGYTGTRCESQV-DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGV 615
G CVD + C C G+ G C +V D+C CR+GG+CL + LC+CP G G+
Sbjct: 442 GTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLG-ANTTLCQCPLGFFGL 497
Query: 616 NCEVNIDDCASNPCTF-------GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGE 668
CE I + PC G C + Y CVC + + C S PC
Sbjct: 498 LCEFEI---TAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNA--SHSLPSPCDSDPCFN 552
Query: 669 GGSCVDGENGFRCLCPPGSLPPLC-LPPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSG 726
GGSC ++ + C CP G C H C+ PC + G C +A G + C C ++G
Sbjct: 553 GGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTG 612
Query: 727 PRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL-SPCTPNPCEHGGR 785
C D+C S PC GGTC + C CPPG GR CE+ SPC +PC +GG
Sbjct: 613 RHCEIG-KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT 671
Query: 786 CESAPGQLPVCSCPQGWQGPRCQQDVDECAGP-----APCGPHGICTNLAGSFSC----- 835
CE C C G+ G RCQ +VD C P A +G ++C
Sbjct: 672 CEDRDTDF-FCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYS 729
Query: 836 --------TC--HGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA 885
C HG ++ P +I++C PCL+GGSCQD V + C C G+ G C
Sbjct: 730 LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCE 789
Query: 886 RDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVN 944
+ DEC ++PC G+C + ++ C CP G+ G HCE ++ C S C +GG C G
Sbjct: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGG 849
Query: 945 SFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 997
++ C+C + G HC+ +DPC S PC G C A++ CTC +TG C
Sbjct: 850 AYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 422 bits (1086), Expect = e-117
Identities = 230/645 (35%), Positives = 296/645 (45%), Gaps = 41/645 (6%)
Query: 589 QPCRHGGKCLDLV----DKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDC 643
+PC +GGKC+D Y C C SG TG C +++++CAS PC G C GIN + C
Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRC 335
Query: 644 VCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEP 703
C GF GP C + C + C GG C C+C G C C+ +P
Sbjct: 336 QCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDP 395
Query: 704 CSHG-ICYDAPGGFRCVCEPGWSGPRCSQS--LARDACESQPCRAGGTCSSDGMGFHCTC 760
C +G C D G + C+C + G RC DAC S PC GGTC G+ C C
Sbjct: 396 CLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCEC 455
Query: 761 PPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE--CAGPA 818
P G G C P C +GGRC A L C CP G+ G C+ ++ C
Sbjct: 456 PEGFMGLDCRERVP-DDCECRNGGRCLGANTTL--CQCPLGFFGLLCEFEITAMPCNMNT 512
Query: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI-NDCDPNPCLNGGSCQDGVGSFSCSCLP 877
C G C GS+ C CH T + + + CD +PC NGGSC S++C C
Sbjct: 513 QCPDGGYCMEHGGSYLCVCH---TDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPR 569
Query: 878 GFAGPRCARDVDE-CLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPD-CSPSSCF 934
GF G C + C S PC GTC + + C+CP + G HCE PD C+ C
Sbjct: 570 GFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCH 629
Query: 935 NGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTG 994
NGGTC + + C C PG++G HC+ PC PC++GG C F C C + G
Sbjct: 630 NGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 995 PQCQTLVDWCSRQPCQ------NGGRCVQTGAYCLCPPGWSG------RLCDIRSLPCRE 1042
+CQ VD + + NG R Y C G+S R+C +
Sbjct: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYA-CDRGYSLSAPSRIRVCQPHGVWSEP 748
Query: 1043 AAA-QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRG 1101
+I Q C GG C D + + C+C G G+HCE E D C A PC++GG+CR
Sbjct: 749 PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN 808
Query: 1102 YMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINE 1161
G Y+C C G+ G +CE +VD C S PCQHGG C YLC CP G CE
Sbjct: 809 LPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVS 868
Query: 1162 DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADI 1206
D C P C G C+ G CTC GYTG C ++
Sbjct: 869 DPCFSSP-------CGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 404 bits (1037), Expect = e-112
Identities = 227/679 (33%), Positives = 316/679 (46%), Gaps = 55/679 (8%)
Query: 173 TCLNTPG--SFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ---SGDLTYDCACLPG 227
T + PG +FR G +V A PC NGG C +G+ +Y C+CL G
Sbjct: 243 TNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSG 302
Query: 228 FEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHN 287
F G+ C ++V++C C NGGTC G+N++ CQCP + G C C + C +
Sbjct: 303 FTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTK--ECQH 360
Query: 288 GGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGL 347
GG C G CVC G+TG +C ++DDC+ C +G +C D V ++ C C GL
Sbjct: 361 GGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL 420
Query: 348 LCH-----LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDV-DECSIGANP 401
C + DAC+S PCH C + +C CP GF G C + V D+C
Sbjct: 421 RCETGDHPVPDACLSAPCHNGGTC--VDADQGYVCECPEGFMGLDCRERVPDDCE----- 473
Query: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC---LSGPCRNQATCLDRIGQFTCICM 458
C + GRC+ + LCQC G+ G CE ++ ++ C + C++ G + C+C
Sbjct: 474 CRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH 532
Query: 459 AGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDE-CASTPCR 517
++ C S PC NGG C + ++C CP GF G C+ C+S PCR
Sbjct: 533 TDHNASHSLP--SPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCR 590
Query: 518 NGAKCVDQPDGYECRCAEGFEGTLCD-RNVDDCSPDPCHH-GRCVDGIASFSCACAPGYT 575
NG C + Y C C F G C+ D C+ PCH+ G C I + C C PG++
Sbjct: 591 NGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFS 650
Query: 576 GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNID-----DCASNPCT 630
G CE C PC +GG C D + C C +G G C+ +D +
Sbjct: 651 GRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLR 710
Query: 631 FGVCRDG-INRYDC-------------VCQPG--FTGPLCNVEINECASSPCGEGGSCVD 674
F R G + Y C VCQP ++ P +EI+EC S PC GGSC D
Sbjct: 711 FNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQD 770
Query: 675 GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSL 733
G+ CLC G C C PC + G C + PG + C C G+ G C +
Sbjct: 771 RVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV 830
Query: 734 ARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS-PCTPNPCEHGGRCESAPGQ 792
DAC+S PC+ GG C S G + C CP G CE +S PC +PC G C ++ G
Sbjct: 831 --DACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGS 888
Query: 793 LPVCSCPQGWQGPRCQQDV 811
C+C G+ G C +++
Sbjct: 889 -HSCTCKVGYTGEDCAKEL 906
Score = 392 bits (1008), Expect = e-108
Identities = 219/650 (33%), Positives = 289/650 (44%), Gaps = 118/650 (18%)
Query: 428 CETDVNECLS-GPCRNQATCLDRI----GQFTCICMAGFTGTYCEVDIDECQSSPCVNGG 482
C + CL+ PC N C+D +TC C++GFTG C +D++EC S PC NGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 483 VCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLC 542
C +N F C CP+GF G TC+ C + C++G +C + C C G+ G C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 543 DRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQ----VDECRSQPCRHGGKC 597
+ +VDDCSPDPC + G CVD + +++C CA + G RCE+ D C S PC +GG C
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 598 LDLVDKYLCRCPSGTTGVNCEVNI-DDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNV 656
+D Y+C CP G G++C + DDC C G G N C C GF G LC
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCEF 501
Query: 657 EI---------------------------------------NECASSPCGEGGSCVDGEN 677
EI + C S PC GGSC ++
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
Query: 678 GFRCLCPPGSLPPLCLPPS-HPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLAR 735
+ C CP G C H C+ PC +G C +A G + C C ++G C
Sbjct: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKP- 620
Query: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL-SPCTPNPCEHGGRCESAPGQLP 794
D+C S PC GGTC + C CPPG GR CE+ SPC +PC +GG CE
Sbjct: 621 DSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF- 679
Query: 795 VCSCPQGWQGPRCQQDVDECAGP------------------------------AP----- 819
C C G+ G RCQ +VD C P AP
Sbjct: 680 FCHCQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRV 738
Query: 820 CGPHGI-----------------------CTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
C PHG+ C + + C C GY G C+ + ++C +
Sbjct: 739 CQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAH 798
Query: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPG 915
PC NGGSC++ G++ C C GF G C +VD C S+PC G C ++ C CP
Sbjct: 799 PCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPES 858
Query: 916 YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP 965
+ G+HCE C S C G C+ S SC C+ GYTG C E P
Sbjct: 859 FFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 384 bits (985), Expect = e-106
Identities = 220/651 (33%), Positives = 290/651 (44%), Gaps = 91/651 (13%)
Query: 741 QPCRAGGTCSSDGM----GFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPV 795
+PC GG C D + + C+C G GR+C L ++ C PC++GG C
Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFR- 334
Query: 796 CSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP 855
C CP G+ GP C+ C C G C GS C C GYTG +C+ D++DC P
Sbjct: 335 CQCPAGFGGPTCETAQSPC-DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSP 393
Query: 856 NPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD----VDECLSNPC-GPGTCTDHVASFTC 910
+PCLNGGSC D VG+++C C F G RC D CLS PC GTC D + C
Sbjct: 394 DPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVC 453
Query: 911 TCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE--ADPC-L 967
CP G+ G C + +PD C NGG C+ G N+ C C G+ G C+ E A PC +
Sbjct: 454 ECPEGFMGLDCRERVPD--DCECRNGGRCL-GANTTLCQCPLGFFGLLCEFEITAMPCNM 510
Query: 968 SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC-VQTGAY-CLCP 1025
+ C GG C + C C +L C PC NGG C +Y C CP
Sbjct: 511 NTQCPDGGYCMEHGGSYLCVCHTDHNASH--SLPSPCDSDPCFNGGSCDAHDDSYTCECP 568
Query: 1026 PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE-QE 1084
G+ G+ C+ R G C+ GG C + ++C CP TG HCE +
Sbjct: 569 RGFHGKHCE----KARPHLCSSGP-----CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGK 619
Query: 1085 VDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARY 1144
D C + PC +GGTC Y+G Y C+C PG++G +CE C PC +GG+C D +
Sbjct: 620 PDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDF 679
Query: 1145 LCSCPPGTLGVLCEINED-------------------------DCGPGPPLDSGPR---- 1175
C C G +G C+ D C G L + R
Sbjct: 680 FCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVC 739
Query: 1176 ----------------------CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGA 1213
CLH G+C D V G+ C C GY G CE + +ECR+
Sbjct: 740 QPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP 799
Query: 1214 CHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTF 1273
C + C P G + C C AGF G C+T + C+S PCQHGG+C GG +
Sbjct: 800 CR--NGGSCRNLP-GAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCE-----SGGGAY 851
Query: 1274 TCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1324
C C + F+G CE V+ C C C + C C G +G C
Sbjct: 852 LCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 369 bits (947), Expect = e-101
Identities = 226/677 (33%), Positives = 291/677 (42%), Gaps = 91/677 (13%)
Query: 807 CQQDVDECAGPAPCGPHGICTN--LAG--SFSCTCHGGYTGPSCDQDINDCDPNPCLNGG 862
C C PC G C + + G S++C+C G+TG C D+N+C PC NGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 863 SCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCTCPPGYGGFHC 921
+C G+ SF C C GF GP C C + C G C S C C GY G C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 922 EQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ---HEA-DPCLSRPCLHGGVC 977
E D+ DCSP C NGG+CVD V +++CLC + G C+ H D CLS PC +GG C
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 978 SAAHPGFRCTCLESFTGPQCQTLV-DWCSRQPCQNGGRCVQTGA-YCLCPPGWSGRLCD- 1034
A G+ C C E F G C+ V D C C+NGGRC+ C CP G+ G LC+
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTTLCQCPLGFFGLLCEF 501
Query: 1035 -IRSLPCR--EAAAQIGVRLEQ-------------------------LCQAGGQCVDEDS 1066
I ++PC G +E C GG C D
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDD 561
Query: 1067 SHYCVCPEGRTGSHCEQ-EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE-DDVD 1124
S+ C CP G G HCE+ C + PC++GGTC+ G Y C C + G +CE D
Sbjct: 562 SYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPD 621
Query: 1125 ECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD 1184
CAS PC +GG+C + +Y C CPPG G CEI C P C++ GTC D
Sbjct: 622 SCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP-------CVNGGTCED 674
Query: 1185 LVGGFRCTCPPGYTGLRCEADI---------------NECRSGAC--HAAHTRDCLQDPG 1227
F C C GY G RC+A++ N R GA +A L P
Sbjct: 675 RDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPS 734
Query: 1228 GGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
C H +S P + C SQPC HGG C+ + C C+ + G CE
Sbjct: 735 RIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAG-----YLCLCSTGYEGAHCE 789
Query: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHG 1347
CR C G C+ P C CP G G C + +C ++PC HG
Sbjct: 790 LERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCET--------EVDACDSSPCQHG 841
Query: 1348 GSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNS 1407
G C A + C C + + G CE + P R C A G C +
Sbjct: 842 GRCESGGGA--YLCVCPESFFGYHCE--TVSDPCFSSPCGGRGYCLASNGSHSCTCK--- 894
Query: 1408 PGCGWDGGDCSLSVGDP 1424
G+ G DC+ + P
Sbjct: 895 --VGYTGEDCAKELFPP 909
Score = 365 bits (938), Expect = e-100
Identities = 214/662 (32%), Positives = 291/662 (43%), Gaps = 128/662 (19%)
Query: 33 LAGPGAAAPPCLDGSPCANGGRC-----TQLPSREAACLCPPGWVGERCQLE-DPCHSGP 86
+ G G CL PC NGG+C T PS C C G+ G RC L+ + C S P
Sbjct: 262 VGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPS--YTCSCLSGFTGRRCHLDVNECASQP 319
Query: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDGRFLCS 145
C G C G F C+CP GF GP C + PC + C HG +C V +G +C
Sbjct: 320 CQNGGTC----THGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQV-ENGSAVCV 374
Query: 146 CPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP----C 201
C GY G +C DVD+C +PC +GG+C++ G++ C C + G CE P C
Sbjct: 375 CQAGYTGAACEMDVDDCS-PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDAC 433
Query: 202 APSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV-DDCPGHRCLNGGTCVDGVNTYNC 260
+PC NGGTC D Y C C GF G +C V DDC C NGG C+ G NT C
Sbjct: 434 LSAPCHNGGTC-VDADQGYVCECPEGFMGLDCRERVPDDC---ECRNGGRCL-GANTTLC 488
Query: 261 QCPPEWTGQFCTEDVDE-------------------------CQLQPNA----------- 284
QCP + G C ++ C NA
Sbjct: 489 QCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSD 548
Query: 285 -CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDD-CATAVCFHGATCHDRVASFYCACPM 342
C NGG+C ++C C G+ G+ C + C++ C +G TC + ++C+CP
Sbjct: 549 PCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPY 608
Query: 343 GKTGLLCHL--DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
TG C + D+C S PCH C G+ C CPPGF+G C+ C +
Sbjct: 609 RFTGRHCEIGKPDSCASGPCHNGGTC--FHYIGKYKCDCPPGFSGRHCEIAPSPCF--RS 664
Query: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN--------------------------- 433
PC + G C + F C C GY G RC+ +V+
Sbjct: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
Query: 434 -------------------------ECLS-GPCRNQ-----ATCLDRIGQFTCICMAGFT 462
+CL CR+Q +C DR+ + C+C G+
Sbjct: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
Query: 463 GTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKC 522
G +CE++ DEC++ PC NGG C++ + C CP+GF G C+ +VD C S+PC++G +C
Sbjct: 785 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRC 844
Query: 523 VDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCES 581
Y C C E F G C+ D C PC G C+ S SC C GYTG C
Sbjct: 845 ESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAK 904
Query: 582 QV 583
++
Sbjct: 905 EL 906
Score = 257 bits (656), Expect = 1e-67
Identities = 196/664 (29%), Positives = 249/664 (37%), Gaps = 163/664 (24%)
Query: 959 CQHEADPCLS-RPCLHGGVCS----AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGG 1013
C H CL+ RPCL+GG C +P + C+CL FTG +C V+ C+ QPCQNGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 1014 RCVQ--TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1071
C C CP G+ G C+ PC CQ GGQC E+ S CV
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKE----------CQHGGQCQVENGSAVCV 374
Query: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDD----VDECA 1127
C G TG+ CE +VD C PC +GG+C +G Y C C + G CE D C
Sbjct: 375 CQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACL 434
Query: 1128 SQPCQHGGSCIDLVARYLCSCPPGTLGVLC-EINEDDCGPGPPLDSGPRCLHNGTCVDLV 1186
S PC +GG+C+D Y+C CP G +G+ C E DDC +G RCL T +
Sbjct: 435 SAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDC----ECRNGGRCLGANTTL--- 487
Query: 1187 GGFRCTCPPGYTGLRCEADIN--------ECRSGA------------CHAAHTRD----- 1221
C CP G+ GL CE +I +C G CH H
Sbjct: 488 ----CQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS 543
Query: 1222 -CLQDP---GGG-------FRCLCHAGFSGPRCQTVLSP-CESQPCQHGGQCRPSPGPGG 1269
C DP GG + C C GF G C+ C S PC++GG C+ + G
Sbjct: 544 PCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE-- 601
Query: 1270 GLTFTCHCAQPFWGPRCE-RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1328
+ C C F G CE SC C G C +C CPPG SG C P
Sbjct: 602 ---YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAP 658
Query: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCP 1388
+ C +PC++GG+C F C C G+ G RC+A E
Sbjct: 659 --------SPCFRSPCVNGGTCEDRDTD--FFCHCQAGYMGRRCQAEVDCGPPEEVKHAT 708
Query: 1389 RAACQAKRGD---QRCDR-----------------------------ECNSPGC------ 1410
+ G CDR EC S C
Sbjct: 709 LRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC 768
Query: 1411 -------------GWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCD----------PA-- 1445
G++G C L + C A C N C PA
Sbjct: 769 QDRVAGYLCLCSTGYEGAHCELERDE----CRAHPCR---NGGSCRNLPGAYVCRCPAGF 821
Query: 1446 ----CSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD---QGCNTEECGWDGL 1498
C + D+ C GGR + Y C + F C+ C + CG G
Sbjct: 822 VGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGY 881
Query: 1499 DCAS 1502
AS
Sbjct: 882 CLAS 885
Score = 117 bits (294), Expect = 1e-25
Identities = 67/173 (38%), Positives = 81/173 (46%), Gaps = 14/173 (8%)
Query: 35 GPGAAAPPCLD-----GSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCA 88
G + P CL+ PC +GG C + CLC G+ G C+LE D C + PC
Sbjct: 743 GVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYL-CLCSTGYEGAHCELERDECRAHPCR 801
Query: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCP 147
G C++ A + CRCP GF G C D C SSPC HG RC G G +LC CP
Sbjct: 802 NGGSCRNLPGA----YVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESG-GGAYLCVCP 856
Query: 148 PGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
+ G C + D C PC G CL + GS C C GYTG C P
Sbjct: 857 ESFFGYHCETVSDPC-FSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 48.9 bits (115), Expect = 6e-05
Identities = 26/63 (41%), Positives = 33/63 (52%), Gaps = 13/63 (20%)
Query: 927 DCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCL------------HG 974
+CS + C NGGTCV G ++ SC C PG+ G C+ A +SRPC G
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE-LACIKVSRPCTRLFSETKAFPVWEG 1368
Query: 975 GVC 977
GVC
Sbjct: 1369 GVC 1371
Score = 48.5 bits (114), Expect = 7e-05
Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 35/206 (16%)
Query: 1333 GASNASCAAA-PCLHGGSCRPAPLA--PFFRCACAQGWTGPRCEA---PAAAPEVSEEPR 1386
G + + C A PCL+GG C + P + C+C G+TG RC A+
Sbjct: 266 GHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGT 325
Query: 1387 CP------RAACQAKRGDQRCD---RECNSPGCGWDGGDCSLSVGDPWRQCEA----LQC 1433
C R C A G C+ C++ C GG C + G C+A C
Sbjct: 326 CTHGINSFRCQCPAGFGGPTCETAQSPCDTKEC-QHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 1434 WRLFNNSRCDPACSSPAC--LYDNFDC-----HAGGRERTCNPVYEKYC--ADHFADGRC 1484
++ DP + +C L N+ C G R T + C A G C
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 1485 ---DQG--CNTEECGWDGLDCASEVP 1505
DQG C E G+ GLDC VP
Sbjct: 445 VDADQGYVCECPE-GFMGLDCRERVP 469
Score = 48.5 bits (114), Expect = 7e-05
Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 852 DCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC 896
+C NPC NGG+C G + SC C PGF G RC + +S PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 46.2 bits (108), Expect = 4e-04
Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 9/70 (12%)
Query: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCS 797
C PC+ GGTC C C PG +GR+CEL PC R S PV
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCT---RLFSETKAFPV-- 1365
Query: 798 CPQGWQGPRC 807
W+G C
Sbjct: 1366 ----WEGGVC 1371
Score = 45.1 bits (105), Expect = 8e-04
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 235
C+ +PC+NGGTC D + C C PGF+G+ CE+
Sbjct: 1311 CSENPCQNGGTCVPGAD-AHSCDCGPGFKGRRCEL 1344
Score = 43.1 bits (100), Expect = 0.003
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Query: 548 DCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPC 591
+CS +PC +G CV G + SC C PG+ G RCE + S+PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV-SRPC 1353
Score = 42.0 bits (97), Expect = 0.007
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
C +PC NGG C + SC C GF G C+L + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 42.0 bits (97), Expect = 0.007
Identities = 14/33 (42%), Positives = 19/33 (57%)
Query: 511 CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD 543
C+ PC+NG CV D + C C GF+G C+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 41.2 bits (95), Expect = 0.012
Identities = 22/44 (50%), Positives = 25/44 (56%), Gaps = 8/44 (18%)
Query: 1004 CSRQPCQNGGRCVQTGA---YCLCPPGWSGRLCDIR----SLPC 1040
CS PCQNGG CV GA C C PG+ GR C++ S PC
Sbjct: 1311 CSENPCQNGGTCVP-GADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 41.2 bits (95), Expect = 0.012
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
C PCQ+GGTC + C+C PG+ G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 40.8 bits (94), Expect = 0.016
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 1111 LPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
LP + + + C+ PCQ+GG+C+ + C C PG G CE+
Sbjct: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
Score = 40.8 bits (94), Expect = 0.016
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPC 168
++P C +PC +G C G D C C PG++GR C ++ +V PC
Sbjct: 1306 NVPGNCSENPCQNGGTCVPGADAHS-CDCGPGFKGRRC--ELACIKVSRPC 1353
Score = 40.0 bits (92), Expect = 0.027
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 239 DCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
+C + C NGGTCV G + ++C C P + G+ C
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 38.9 bits (89), Expect = 0.059
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 9/51 (17%)
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE----RVARSCREL 1296
C PCQ+GG C P G +C C F G RCE +V+R C L
Sbjct: 1311 CSENPCQNGGTCVP-----GADAHSCDCGPGFKGRRCELACIKVSRPCTRL 1356
Score = 38.1 bits (87), Expect = 0.10
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 12/62 (19%)
Query: 623 DCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVE-----------INECASSPCGEGG 670
+C+ NPC G C G + + C C PGF G C + +E + P EGG
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 671 SC 672
C
Sbjct: 1370 VC 1371
Score = 38.1 bits (87), Expect = 0.10
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCT 630
C PC++GG C+ D + C C G G CE+ S PCT
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPCT 1354
Score = 37.7 bits (86), Expect = 0.13
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
Query: 47 SPCANGGRCTQLPSREA-ACLCPPGWVGERCQLEDPCHSGPC 87
+PC NGG C +P +A +C C PG+ G RC+L S PC
Sbjct: 1314 NPCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 37.4 bits (85), Expect = 0.17
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 11/61 (18%)
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVD-----------IDECQSSPCVNGGV 483
C PC+N TC+ +C C GF G CE+ E ++ P GGV
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 484 C 484
C
Sbjct: 1371 C 1371
Score = 37.4 bits (85), Expect = 0.17
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 4/43 (9%)
Query: 661 CASSPCGEGGSCVDGENGFRCLCPPG----SLPPLCLPPSHPC 699
C+ +PC GG+CV G + C C PG C+ S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 37.4 bits (85), Expect = 0.17
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPC 440
NPC++ G CV + C CG G+ G RCE + +S PC
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 36.6 bits (83), Expect = 0.29
Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 283 NACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPM 342
N C NGGTC HSC C G+ G C C + R+ S A P+
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPV 1365
Query: 343 GKTGLLCHL--------DDACVSNPCHEDAICDT 368
+ G+ H+ D C C ++ T
Sbjct: 1366 WEGGVCHHVYKRVYRVHQDICFKESCESTSLKKT 1399
Score = 36.2 bits (82), Expect = 0.38
Identities = 19/48 (39%), Positives = 21/48 (43%)
Query: 1156 LCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
L E D G P S C + GTCV C C PG+ G RCE
Sbjct: 1296 LPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 36.2 bits (82), Expect = 0.38
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 6/45 (13%)
Query: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
G+ PG +C+ PC +GG+C P A C C G+ G RCE
Sbjct: 1305 GNVPG----NCSENPCQNGGTCVPG--ADAHSCDCGPGFKGRRCE 1343
Score = 35.8 bits (81), Expect = 0.50
Identities = 18/47 (38%), Positives = 20/47 (42%), Gaps = 4/47 (8%)
Query: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPC 128
C PC G C V G SC C GF+G C L +S PC
Sbjct: 1311 CSENPCQNGGTC----VPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 35.4 bits (80), Expect = 0.66
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 3/35 (8%)
Query: 775 CTPNPCEHGGRCESAPG-QLPVCSCPQGWQGPRCQ 808
C+ NPC++GG C PG C C G++G RC+
Sbjct: 1311 CSENPCQNGGTC--VPGADAHSCDCGPGFKGRRCE 1343
Score = 35.4 bits (80), Expect = 0.66
Identities = 18/57 (31%), Positives = 24/57 (42%), Gaps = 11/57 (19%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV----PCA-------PSPCRNGGTC 212
PC++GGTC+ + C C G+ G CE + PC P GG C
Sbjct: 1315 PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1371
Score = 34.3 bits (77), Expect = 1.5
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 7/68 (10%)
Query: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 1025
C PC +GG C C C F G +C+ SR PC +T A+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSR-PCTR--LFSETKAF---- 1363
Query: 1026 PGWSGRLC 1033
P W G +C
Sbjct: 1364 PVWEGGVC 1371
Score = 34.3 bits (77), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 891 CLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCE 922
C NPC GTC + +C C PG+ G CE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 33.9 bits (76), Expect = 1.9
Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 11/59 (18%)
Query: 1052 EQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE----QEVDPCL-------AQPCQHGGTC 1099
E CQ GG CV +H C C G G CE + PC A P GG C
Sbjct: 1313 ENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVC 1371
Score = 32.3 bits (72), Expect = 5.6
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 4/46 (8%)
Query: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPC 743
C+ PC +G C C C PG+ G RC + + S+PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK---VSRPC 1353
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 351 bits (900), Expect = 5e-96
Identities = 170/456 (37%), Positives = 236/456 (51%), Gaps = 39/456 (8%)
Query: 311 CSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGL---LCHLDDACVSNPCHEDAICD 367
C++N C + C + +TC D C+C L ++ D C SNPC A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 368 TNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR 427
P +C CPPG++G C+ + C G N C+H G C +C C GY G
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSC--GKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 428 CETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR 487
CE D +EC S PC+N A C D I ++C C+ G+ G +C++++DEC S PC N C +
Sbjct: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
Query: 488 VNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVD 547
+ ++C CP +SG C+L++DEC S PC NGA C D Y C CA GF G C+ N D
Sbjct: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
Query: 548 DCSPDPC-HHGRCVDGIASFSCAC-APGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
+C+ PC H G CVDG +SC C G+TGT CE+ + C S+PC + C D VD Y
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 606 CRCPSGTTGVNCEVNIDDCASNPC-TFGVCRD--------------------GINRYDCV 644
C C G TG CE+++++C SNPC + G C + + Y C+
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 645 CQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPL------CLPPSHP 698
CQPGFTG C ++NEC+S+PC GG+C + + C CP +L C
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLG 444
Query: 699 CAHEPC-SHGIC----YDAPGGFRCVCEPGWSGPRC 729
C H+ C ++G C D GF C+C G++G C
Sbjct: 445 CTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 329 bits (843), Expect = 2e-89
Identities = 172/459 (37%), Positives = 228/459 (49%), Gaps = 44/459 (9%)
Query: 82 CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDG 140
C S C C+ SC DC ++ DPC S+PC A C P
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDC--SCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGE 91
Query: 141 R-FLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
R FLC CPPGY G C + + C C+HGG C P C CPAGY G CE
Sbjct: 92 RSFLCKCPPGYSGTICETTIGSCGKNS-CQHGGICHQDPIYPVCICPAGYAGRFCEIDHD 150
Query: 200 PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 259
CA SPC+NG C Q G Y C C+PG++G++C++ VD+C C N TC++ + Y
Sbjct: 151 ECASSPCQNGAVC-QDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYT 209
Query: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
C CP ++G C ++DEC QP C NG TC + LG + C C G+ G+ C N D+CA
Sbjct: 210 CICPHNYSGVNCELEIDECWSQP--CLNGATCQDALGAYFCDCAPGFLGDHCELNTDECA 267
Query: 320 TAVCFHGATCHDRVASFYCACP-MGKTGLLCH-LDDACVSNPCHEDAICDTNPVNGRAIC 377
+ C HG C D + C C G TG C L C S PCH +A C+ + N C
Sbjct: 268 SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN--YTC 325
Query: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCV--------------------NTQGSFLC 417
C PG+TG C+ D++EC+ +NPC+ G CV + ++C
Sbjct: 326 HCWPGYTGAQCEIDLNECN--SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVC 383
Query: 418 QCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCIC------MAGFTGTYCEVDID 471
C G+TG CE DVNEC S PC+N TC + G +TC C + G C +
Sbjct: 384 ICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILL 443
Query: 472 ECQSSPCVNGGVC----KDRVNGFSCTCPSGFSGSTCQL 506
C C+N G C +D +GFSC CPSG++GS C++
Sbjct: 444 GCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 320 bits (820), Expect = 1e-86
Identities = 162/462 (35%), Positives = 227/462 (49%), Gaps = 43/462 (9%)
Query: 155 CRSDVDECRVGEPCRHGGTCLNTPGSFRCQCP--AGYTGPLCENPAVPCAPSPCRNGGTC 212
C + C + C++ TC + C C A C+N PC +PC+ TC
Sbjct: 27 CNKNNTRC-LSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATC 85
Query: 213 RQS-GDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
+ G+ ++ C C PG+ G CE + C + C +GG C C CP + G+FC
Sbjct: 86 VNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
Query: 272 TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHD 331
D DEC P C NG C + + G+SC CV G+ G C +D+CA+ C + ATC +
Sbjct: 146 EIDHDECASSP--CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLN 203
Query: 332 RVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 390
+ + C CP +G+ C L+ D C S PC A C G C C PGF G C+
Sbjct: 204 EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQD--ALGAYFCDCAPGFLGDHCEL 261
Query: 391 DVDECSIGANPCEHLGRCVNTQGSFLCQC-GRGYTGPRCETDVNECLSGPCRNQATCLDR 449
+ DEC+ + PC H G CV+ + + C C G G+TG CET + C S PC N ATC D
Sbjct: 262 NTDECA--SQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS 319
Query: 450 IGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKD--------------------RVN 489
+ +TC C G+TG CE+D++EC S+PC + G C + +
Sbjct: 320 VDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEAS 379
Query: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEG------FEGTLCD 543
G+ C C GF+G C+ DV+EC+S PC+NG C + P Y C C + G C
Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCS 439
Query: 544 RNVDDCSPDPC-HHGRCV----DGIASFSCACAPGYTGTRCE 580
+ C+ C ++G C+ DG FSC C GYTG+ CE
Sbjct: 440 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 299 bits (766), Expect = 2e-80
Identities = 158/462 (34%), Positives = 213/462 (46%), Gaps = 81/462 (17%)
Query: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG--QFCTEDVDECQLQPNACHNGGT 290
C N C + C N TC D +C C + C D C P C T
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSAT 84
Query: 291 CFNTLGGHS--CVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLL 348
C NT G S C C G++G C I C C HG CH C CP G G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 349 CHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGR 407
C +D D C S+PC A+C ++G + C C PG+ G CD +VDEC+ ++PC++
Sbjct: 145 CEIDHDECASSPCQNGAVCQDG-IDGYS-CFCVPGYQGRHCDLEVDECA--SDPCKNEAT 200
Query: 408 CVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCE 467
C+N G + C C Y+G CE +++EC S PC N ATC D +G + C C GF G +CE
Sbjct: 201 CLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Query: 468 VDIDECQSSPCVNGGVCKDRVNGFSCTCP-SGFSGSTCQLDVDECASTPCRNGAKCVDQP 526
++ DEC S PC++GG+C D N +SC C SGF+G+ C+ + C S PC N A C D
Sbjct: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 527 DGYECRCAEGFEGTLCDRNVDDCSPDPCH-HGRCVD-----------GIAS--------- 565
D Y C C G+ G C+ ++++C+ +PC +G CV+ G+ S
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 566 FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP---------------- 609
+ C C PG+TG CE V+EC S PC++GG C +L Y C CP
Sbjct: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440
Query: 610 --------------------------------SGTTGVNCEV 619
SG TG CE+
Sbjct: 441 ILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 298 bits (762), Expect = 5e-80
Identities = 158/486 (32%), Positives = 224/486 (46%), Gaps = 45/486 (9%)
Query: 617 CEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTG--PLCNVEINECASSPCGEGGSCV 673
C N C SN C C+D DC C C+ + C S+PC +CV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 674 D--GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCS 730
+ GE F C CPPG +C C C HG IC+ P C+C G++G C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 731 QSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESA 789
+ D C S PC+ G C G+ C C PG QGR C+L + C +PC++ C +
Sbjct: 147 --IDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
Query: 790 PGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD 849
G+ C CP + G C+ ++DEC PC C + G++ C C G+ G C+ +
Sbjct: 205 IGRY-TCICPHNYSGVNCELEIDEC-WSQPCLNGATCQDALGAYFCDCAPGFLGDHCELN 262
Query: 850 INDCDPNPCLNGGSCQDGVGSFSCSCL-PGFAGPRCARDVDECLSNPC-GPGTCTDHVAS 907
++C PCL+GG C DG +SC+C GF G C + C S PC TC D V +
Sbjct: 263 TDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDN 322
Query: 908 FTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD--------------------GVNSFS 947
+TC C PGY G CE DL +C+ + C + G CV+ + +
Sbjct: 323 YTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 948 CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTC------LESFTGPQCQTLV 1001
C+C+PG+TG HC+ + + C S PC +GG C + C C + G C ++
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
Query: 1002 DWCSRQPCQNGGRCV------QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLC 1055
C+ Q C N G C+ Q G CLCP G++G LC+I + E + V+ +
Sbjct: 443 LGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEGDGFLWVKSGSVT 502
Query: 1056 QAGGQC 1061
G C
Sbjct: 503 TKGSVC 508
Score = 284 bits (727), Expect = 6e-76
Identities = 158/477 (33%), Positives = 206/477 (43%), Gaps = 46/477 (9%)
Query: 921 CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH--CQHEADPCLSRPCLHGGVC- 977
C ++ C +SC N TC D C C C + DPC S PC C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 978 -SAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCD 1034
+ F C C ++G C+T + C + CQ+GG C Q Y C+CP G++GR C+
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCE 146
Query: 1035 IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQ 1094
I C + CQ G C D + C C G G HC+ EVD C + PC+
Sbjct: 147 IDHDECASSP----------CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCK 196
Query: 1095 HGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLG 1154
+ TC +G Y C C Y+G NCE ++DEC SQPC +G +C D + Y C C PG LG
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 1155 VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP-PGYTGLRCEADINECRSGA 1213
CE+N D+C P CLH G CVD + C C G+TG CE + C S
Sbjct: 257 DHCELNTDECASQP-------CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP 309
Query: 1214 CHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQC--RPSPGPGGGL 1271
CH T +D + C C G++G +C+ L+ C S PCQ G+C S G +
Sbjct: 310 CHNNAT---CEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRI 366
Query: 1272 T-------------FTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPG 1318
T + C C F G CE C C G C+ P C CP
Sbjct: 367 TGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCP-- 424
Query: 1319 LSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP--APLAPFFRCACAQGWTGPRCE 1373
S + G C CL+ G+C P F C C G+TG CE
Sbjct: 425 FDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 283 bits (723), Expect = 2e-75
Identities = 151/462 (32%), Positives = 208/462 (45%), Gaps = 83/462 (17%)
Query: 464 TYCEVDIDECQSSPCVNGGVCKD------------------------------------- 486
++C + C S+ C N CKD
Sbjct: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 487 -----RVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTL 541
F C CP G+SG+ C+ + C C++G C P C C G+ G
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRF 144
Query: 542 CDRNVDDCSPDPCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
C+ + D+C+ PC +G C DGI +SC C PGY G C+ +VDEC S PC++ CL+
Sbjct: 145 CEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNE 204
Query: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYDCVCQPGFTGPLCNVEIN 659
+ +Y C CP +GVNCE+ ID+C S PC G C+D + Y C C PGF G C + +
Sbjct: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
Query: 660 ECASSPCGEGGSCVDGENGFRCLCP-PGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFR 717
ECAS PC GG CVDGEN + C C G C C +PC ++ C D+ +
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYT 324
Query: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSS--------------------DGMGFH 757
C C PG++G +C L + C S PC++ G C + G+
Sbjct: 325 CHCWPGYTGAQCEIDL--NECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYV 382
Query: 758 CTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCP-----QGWQGPRCQQDV 811
C C PG G CE ++ C+ NPC++GG CE+ PG C CP + + G R D+
Sbjct: 383 CICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNY-TCHCPFDNLSRTFYGGRDCSDI 441
Query: 812 ------DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
+C C PH + FSC C GYTG C+
Sbjct: 442 LLGCTHQQCLNNGTCIPH--FQDGQHGFSCLCPSGYTGSLCE 481
Score = 261 bits (666), Expect = 7e-69
Identities = 149/462 (32%), Positives = 194/462 (41%), Gaps = 90/462 (19%)
Query: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPA---PCGPHGICTNLAG 831
C N C++ C+ CSC +D D P PC C N G
Sbjct: 34 CLSNSCQNNSTCKDFSKDND-CSCSD--TANNLDKDCDNMKDPCFSNPCQGSATCVNTPG 90
Query: 832 --SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVD 889
SF C C GY+G C+ I C N C +GG C C C G+AG C D D
Sbjct: 91 ERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDHD 150
Query: 890 ECLSNPCGPGT-CTDHVASFTCTCPPGYGGFH---------------------------- 920
EC S+PC G C D + ++C C PGY G H
Sbjct: 151 ECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRYTC 210
Query: 921 ----------CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRP 970
CE ++ +C C NG TC D + ++ C C PG+ G HC+ D C S+P
Sbjct: 211 ICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECASQP 270
Query: 971 CLHGGVCSAAHPGFRCTCLES-FTGPQCQTLVDWCSRQPCQNGGRCVQT--GAYCLCPPG 1027
CLHGG+C + C C S FTG C+TL+ C +PC N C + C C PG
Sbjct: 271 CLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPG 330
Query: 1028 WSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD--------------------EDSS 1067
++G C+I C CQ+ G+CV+ E S
Sbjct: 331 YTGAQCEIDLNECN----------SNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASG 380
Query: 1068 HYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCEC------LPGYNGDNCED 1121
+ C+C G TG HCE++V+ C + PCQ+GGTC G Y C C Y G +C D
Sbjct: 381 YVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSD 440
Query: 1122 DVDECASQPCQHGGSCI----DLVARYLCSCPPGTLGVLCEI 1159
+ C Q C + G+CI D + C CP G G LCEI
Sbjct: 441 ILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 249 bits (635), Expect = 3e-65
Identities = 154/462 (33%), Positives = 203/462 (43%), Gaps = 89/462 (19%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPP--GWVGERCQ-LEDPCHSGPCAGRGVCQSSVVA 99
CL S C N C S++ C C + + C ++DPC S PC G C ++
Sbjct: 34 CLSNS-CQNNSTCKDF-SKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNT--P 89
Query: 100 GTARFSCRCPRGFRG---------------------------PDCSLP------------ 120
G F C+CP G+ G P C P
Sbjct: 90 GERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEIDH 149
Query: 121 DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGS 180
D C SSPC +GA C G DG + C C PGYQGR C +VDEC +PC++ TCLN G
Sbjct: 150 DECASSPCQNGAVCQDGIDG-YSCFCVPGYQGRHCDLEVDEC-ASDPCKNEATCLNEIGR 207
Query: 181 FRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDC 240
+ C CP Y+G CE C PC NG TC Q Y C C PGF G +CE+N D+C
Sbjct: 208 YTCICPHNYSGVNCELEIDECWSQPCLNGATC-QDALGAYFCDCAPGFLGDHCELNTDEC 266
Query: 241 PGHRCLNGGTCVDGVNTYNCQCPPE-WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
CL+GG CVDG N Y+C C +TG C + C +P CHN TC +++ ++
Sbjct: 267 ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKP--CHNNATCEDSVDNYT 324
Query: 300 CVCVNGWTGESCSQNIDDCATAVCFHGATC--------------------HDRVASFYCA 339
C C G+TG C ++++C + C C + + + C
Sbjct: 325 CHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCI 384
Query: 340 CPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCP-----PGFTGGACDQDVD 393
C G TG+ C D + C SNPC C+ P G C CP F GG +D
Sbjct: 385 CQPGFTGIHCEEDVNECSSNPCQNGGTCENLP--GNYTCHCPFDNLSRTFYGG---RDCS 439
Query: 394 ECSIGA--NPCEHLGRCV----NTQGSFLCQCGRGYTGPRCE 429
+ +G C + G C+ + Q F C C GYTG CE
Sbjct: 440 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 179 bits (454), Expect = 3e-44
Identities = 77/195 (39%), Positives = 109/195 (55%), Gaps = 9/195 (4%)
Query: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
+N C+ NPCL+GG+C+D S+ CSC G++G C ++DEC SNPC G C+D VA++
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH 1199
Query: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC--- 966
CTC PGY G +CE D+ +C C NG TC+ N +SCLC +TG C+ P
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 967 ----LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGA 1020
+ C +GG C+ +C C FTG C+ +D C+ PC NGG C +
Sbjct: 1260 GNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKF 1319
Query: 1021 YCLCPPGWSGRLCDI 1035
CLC ++G C++
Sbjct: 1320 QCLCDVAFAGERCEV 1334
Score = 176 bits (447), Expect = 2e-43
Identities = 77/200 (38%), Positives = 112/200 (56%), Gaps = 9/200 (4%)
Query: 432 VNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF 491
+N C S PC + C D + C C G++G +CE++IDEC S+PC++G C DRV +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAY 1198
Query: 492 SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV----- 546
CTC G++G C++D+D C S C NGA C+ +GY C C F G C ++
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 547 --DDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
++ + C++G C + C C PG+TG CE +DEC S PC +GG C DL++K
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
Query: 604 YLCRCPSGTTGVNCEVNIDD 623
+ C C G CEV++ D
Sbjct: 1319 FQCLCDVAFAGERCEVDLAD 1338
Score = 167 bits (423), Expect = 1e-40
Identities = 129/474 (27%), Positives = 166/474 (35%), Gaps = 93/474 (19%)
Query: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNG--DNCEDDVDECASQPCQHGGS 1136
S C + CL+ CQ+ TC+ + C C N +C++ D C S PCQ +
Sbjct: 25 SFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 1137 CIDLVAR--YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCP 1194
C++ +LC CPPG G +CE CG C H G C C CP
Sbjct: 85 CVNTPGERSFLCKCPPGYSGTICETTIGSCGKN-------SCQHGGICHQDPIYPVCICP 137
Query: 1195 PGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
GY G CE D +EC S C QD G+ C C G+ G C + C S P
Sbjct: 138 AGYAGRFCEIDHDECASSPCQNGAV---CQDGIDGYSCFCVPGYQGRHCDLEVDECASDP 194
Query: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCA 1314
C++ C G +TC C + G CE C C G CQ C
Sbjct: 195 CKNEATCLNEIG-----RYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCD 249
Query: 1315 CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCAC-AQGWTGPRCE 1373
C PG G C + CA+ PCLHGG C + C C G+TG CE
Sbjct: 250 CAPGFLGDHCE--------LNTDECASQPCLHGGLCVDGENR--YSCNCTGSGFTGTHCE 299
Query: 1374 APAAAPEVSEEPRCPRAACQAKRGDQRCD--------------RECNSPGCGWDGGDCSL 1419
P +P A C+ + C ECNS C +G L
Sbjct: 300 --TLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVEL 357
Query: 1420 SVGDPWRQCEALQ--------------CWRLFNNSRCDP---ACSSPAC--------LYD 1454
S + + L C F C+ CSS C L
Sbjct: 358 SSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPG 417
Query: 1455 NFDCHA----------GGRERTCNPVY----------EKYCADHFADGRCDQGC 1488
N+ CH GGR+ C+ + C HF DG+ C
Sbjct: 418 NYTCHCPFDNLSRTFYGGRD--CSDILLGCTHQQCLNNGTCIPHFQDGQHGFSC 469
Score = 166 bits (420), Expect = 2e-40
Identities = 76/198 (38%), Positives = 102/198 (51%), Gaps = 10/198 (5%)
Query: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRY 641
Q++ C S PC HGG C D+ Y C CP G +G +CE+NID+C SNPC G C D + Y
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY 1198
Query: 642 DCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP---PSHP 698
C C+PG+TG C V+I+ C S C G +C+ NG+ CLC C PS
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 699 CAHEPC-----SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG 753
C +E + G C + +C+C PG++G C + + D C S PC GG C
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI--DECASDPCVNGGLCQDLL 1316
Query: 754 MGFHCTCPPGVQGRQCEL 771
F C C G +CE+
Sbjct: 1317 NKFQCLCDVAFAGERCEV 1334
Score = 165 bits (417), Expect = 5e-40
Identities = 79/211 (37%), Positives = 106/211 (50%), Gaps = 16/211 (7%)
Query: 769 CELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTN 828
C L+ C NPC HGG CE CSCP GW G C+ ++DEC PC HG C++
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYH-CSCPLGWSGKHCELNIDECFS-NPC-IHGNCSD 1193
Query: 829 LAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV 888
++ CTC GYTG +C+ DI++C + C NG +C +SC C F G C +
Sbjct: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQ-- 1251
Query: 889 DECLSNPCG----------PGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGT 938
S CG G CT+ C C PG+ G CE+D+ +C+ C NGG
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
Query: 939 CVDGVNSFSCLCRPGYTGAHCQHE-ADPCLS 968
C D +N F CLC + G C+ + AD +S
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVDLADDLIS 1342
Score = 162 bits (409), Expect = 5e-39
Identities = 74/186 (39%), Positives = 97/186 (52%), Gaps = 8/186 (4%)
Query: 506 LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIAS 565
L ++ C S PC +G C D Y C C G+ G C+ N+D+C +PC HG C D +A+
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 566 FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVN--IDD 623
+ C C PGYTG CE +D C+S C +G C+ + Y C C TG C +
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 624 CASNPCTFGVCRDGIN------RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
N T C +G N C+C+PGFTG C +I+ECAS PC GG C D N
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 678 GFRCLC 683
F+CLC
Sbjct: 1318 KFQCLC 1323
Score = 161 bits (407), Expect = 8e-39
Identities = 71/200 (35%), Positives = 112/200 (56%), Gaps = 10/200 (5%)
Query: 468 VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPD 527
+ ++ C S+PC++GG C+D + + C+CP G+SG C+L++DEC S PC +G C D+
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVA 1196
Query: 528 GYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQ---- 582
Y C C G+ G C+ ++D+C C +G C+ +SC C +TG C
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 583 ---VDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGI 638
+E + C +GG C + + C C G TG CE +ID+CAS+PC G+C+D +
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 639 NRYDCVCQPGFTGPLCNVEI 658
N++ C+C F G C V++
Sbjct: 1317 NKFQCLCDVAFAGERCEVDL 1336
Score = 158 bits (400), Expect = 5e-38
Identities = 71/191 (37%), Positives = 100/191 (52%), Gaps = 7/191 (3%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226
PC HGG C + S+ C CP G++G CE C +PC +G + Y C C P
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVA--AYHCTCEP 1204
Query: 227 GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN--- 283
G+ G NCEV++D+C H+C NG TC+ N Y+C C +TG+FC + + N
Sbjct: 1205 GYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKT 1264
Query: 284 --ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACP 341
C+NGG C C+C G+TGE C ++ID+CA+ C +G C D + F C C
Sbjct: 1265 NLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCD 1324
Query: 342 MGKTGLLCHLD 352
+ G C +D
Sbjct: 1325 VAFAGERCEVD 1335
Score = 157 bits (397), Expect = 1e-37
Identities = 74/199 (37%), Positives = 104/199 (52%), Gaps = 13/199 (6%)
Query: 318 CATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAI 376
C + C HG C D +S++C+CP+G +G C L+ D C SNPC D
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYH--- 1199
Query: 377 CTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV---- 432
CTC PG+TG C+ D+D C ++ C + C++ + C C +TG C
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQ--SHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 433 ---NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVN 489
NE + C N C + + C+C GFTG +CE DIDEC S PCVNGG+C+D +N
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 490 GFSCTCPSGFSGSTCQLDV 508
F C C F+G C++D+
Sbjct: 1318 KFQCLCDVAFAGERCEVDL 1336
Score = 150 bits (378), Expect = 2e-35
Identities = 77/206 (37%), Positives = 98/206 (47%), Gaps = 10/206 (4%)
Query: 1046 QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGG 1105
Q+ V C GG C D SS++C CP G +G HCE +D C + PC H G C +
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAA 1197
Query: 1106 YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLC---EINED 1162
Y C C PGY G NCE D+D C S C +G +CI Y C C G C +
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 1163 DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDC 1222
CG + C + G C + +C C PG+TG CE DI+EC S C
Sbjct: 1258 VCGNE---KTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPC---VNGGL 1311
Query: 1223 LQDPGGGFRCLCHAGFSGPRCQTVLS 1248
QD F+CLC F+G RC+ L+
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVDLA 1337
Score = 148 bits (374), Expect = 5e-35
Identities = 75/211 (35%), Positives = 96/211 (45%), Gaps = 12/211 (5%)
Query: 733 LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPG 791
L + C S PC GG C +HC+CP G G+ CEL + C NPC HG +
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 792 QLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI- 850
C+C G+ G C+ D+D C C C + +SC C G +TG C Q
Sbjct: 1198 YH--CTCEPGYTGVNCEVDIDNCQSHQ-CANGATCISHTNGYSCLCFGNFTGKFCRQSRL 1254
Query: 851 ------NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTD 903
N+ C NGG+C + C C PGF G C +D+DEC S+PC G C D
Sbjct: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 904 HVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
+ F C C + G CE DL D S F
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDLADDLISDIF 1345
Score = 140 bits (352), Expect = 2e-32
Identities = 70/208 (33%), Positives = 99/208 (47%), Gaps = 16/208 (7%)
Query: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARC 134
C + C+S PC G C+ + + C CP G+ G C L D C S+PC HG C
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIY----SSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NC 1191
Query: 135 SVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
S + C+C PGY G +C D+D C+ C +G TC++ + C C +TG C
Sbjct: 1192 S-DRVAAYHCTCEPGYTGVNCEVDIDNCQ-SHQCANGATCISHTNGYSCLCFGNFTGKFC 1249
Query: 195 ENPAVPCAPS-------PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLN 247
+P C NGG C + C C PGF G+ CE ++D+C C+N
Sbjct: 1250 RQSRLPSTVCGNEKTNLTCYNGGNCTEF-QTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
Query: 248 GGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
GG C D +N + C C + G+ C D+
Sbjct: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 138 bits (348), Expect = 6e-32
Identities = 67/206 (32%), Positives = 96/206 (46%), Gaps = 18/206 (8%)
Query: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY-CLC 1024
C S PCLHGG C + + C+C ++G C+ +D C PC +G + AY C C
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAYHCTC 1202
Query: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQE 1084
PG++G C++ C+ C G C+ + + C+C TG C Q
Sbjct: 1203 EPGYTGVNCEVDIDNCQS----------HQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
Query: 1085 VDPCLA-------QPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSC 1137
P C +GG C + C C PG+ G+ CE D+DECAS PC +GG C
Sbjct: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC 1312
Query: 1138 IDLVARYLCSCPPGTLGVLCEINEDD 1163
DL+ ++ C C G CE++ D
Sbjct: 1313 QDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 137 bits (346), Expect = 9e-32
Identities = 72/205 (35%), Positives = 96/205 (46%), Gaps = 12/205 (5%)
Query: 656 VEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGG 715
+++N C S+PC GG+C D + + C CP G C C PC HG C D
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAA 1197
Query: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQG---RQCELL 772
+ C CEPG++G C + D C+S C G TC S G+ C C G RQ L
Sbjct: 1198 YHCTCEPGYTGVNCEVDI--DNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLP 1255
Query: 773 SPCTPN-----PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT 827
S N C +GG C +L C C G+ G C++D+DECA PC G+C
Sbjct: 1256 STVCGNEKTNLTCYNGGNCTEFQTELK-CMCRPGFTGEWCEKDIDECASD-PCVNGGLCQ 1313
Query: 828 NLAGSFSCTCHGGYTGPSCDQDIND 852
+L F C C + G C+ D+ D
Sbjct: 1314 DLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 137 bits (345), Expect = 1e-31
Identities = 71/210 (33%), Positives = 99/210 (47%), Gaps = 21/210 (10%)
Query: 1084 EVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR 1143
+++ C + PC HGG C Y C C G++G +CE ++DEC S PC H G+C D VA
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH-GNCSDRVAA 1197
Query: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Y C+C PG GV CE++ D+C +C + TC+ G+ C C +TG C
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNC-------QSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Query: 1204 ADINECRSGACHAAHTRDCLQDPGG------GFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
+ S C T + G +C+C GF+G C+ + C S PC +
Sbjct: 1251 Q--SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
Query: 1258 GGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
GG C+ F C C F G RCE
Sbjct: 1309 GGLCQDLLN-----KFQCLCDVAFAGERCE 1333
Score = 134 bits (338), Expect = 8e-31
Identities = 69/205 (33%), Positives = 100/205 (48%), Gaps = 15/205 (7%)
Query: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
C + CL+GG C D ++Y+C CP W+G+ C ++DEC P H G C + + +
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-CIH--GNCSDRVAAYH 1199
Query: 300 CVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC---HLDDACV 356
C C G+TG +C +ID+C + C +GATC + C C TG C L
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVC 1259
Query: 357 SN-----PCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNT 411
N C+ C C C PGFTG C++D+DEC+ ++PC + G C +
Sbjct: 1260 GNEKTNLTCYNGGNC--TEFQTELKCMCRPGFTGEWCEKDIDECA--SDPCVNGGLCQDL 1315
Query: 412 QGSFLCQCGRGYTGPRCETDVNECL 436
F C C + G RCE D+ + L
Sbjct: 1316 LNKFQCLCDVAFAGERCEVDLADDL 1340
Score = 134 bits (336), Expect = 1e-30
Identities = 74/205 (36%), Positives = 96/205 (46%), Gaps = 13/205 (6%)
Query: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFH 757
C PC HG C D + C C GWSG C ++ D C S PC G CS +H
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNI--DECFSNPC-IHGNCSDRVAAYH 1199
Query: 758 CTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQD---VDE 813
CTC PG G CE+ + C + C +G C S C C + G C+Q
Sbjct: 1200 CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYS-CLCFGNFTGKFCRQSRLPSTV 1258
Query: 814 CAGPAP---CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS 870
C C G CT C C G+TG C++DI++C +PC+NGG CQD +
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNK 1318
Query: 871 FSCSCLPGFAGPRCARDV-DECLSN 894
F C C FAG RC D+ D+ +S+
Sbjct: 1319 FQCLCDVAFAGERCEVDLADDLISD 1343
Score = 131 bits (330), Expect = 7e-30
Identities = 73/206 (35%), Positives = 94/206 (45%), Gaps = 23/206 (11%)
Query: 1126 CASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
C S PC HGG+C D+ + Y CSCP G G CE+N D+C P C+H G C D
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNP-------CIH-GNCSDR 1194
Query: 1186 VGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
V + CTC PGYTG+ CE DI+ C+S C A+ C+ G + CLC F+G C+
Sbjct: 1195 VAAYHCTCEPGYTGVNCEVDIDNCQSHQC--ANGATCISHTNG-YSCLCFGNFTGKFCRQ 1251
Query: 1246 VLSP---CESQP----CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQC 1298
P C ++ C +GG C C C F G CE+ C C
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQ-----TELKCMCRPGFTGEWCEKDIDECASDPC 1306
Query: 1299 PVGVPCQQTPRGPRCACPPGLSGPSC 1324
G CQ +C C +G C
Sbjct: 1307 VNGGLCQDLLNKFQCLCDVAFAGERC 1332
Score = 124 bits (311), Expect = 1e-27
Identities = 69/203 (33%), Positives = 94/203 (46%), Gaps = 16/203 (7%)
Query: 45 DGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTAR 103
+ +PC +GG C + S C CP GW G+ C+L D C S PC G C V A
Sbjct: 1144 NSNPCLHGGNCEDIYS-SYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAA---- 1197
Query: 104 FSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSD---- 158
+ C C G+ G +C + D C S CA+GA C +G + C C + G+ CR
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNG-YSCLCFGNFTGKFCRQSRLPS 1256
Query: 159 --VDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSG 216
+ C +GG C +C C G+TG CE CA PC NGG C+
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLL 1316
Query: 217 DLTYDCACLPGFEGQNCEVNVDD 239
+ + C C F G+ CEV++ D
Sbjct: 1317 N-KFQCLCDVAFAGERCEVDLAD 1338
Score = 110 bits (275), Expect = 2e-23
Identities = 61/215 (28%), Positives = 91/215 (42%), Gaps = 26/215 (12%)
Query: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
CLH G C D+ + C+CP G++G CE +I+EC S C + D + + C C
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRV----AAYHCTCE 1203
Query: 1236 AGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCER------- 1288
G++G C+ + C+S C +G C ++C C F G C +
Sbjct: 1204 PGYTGVNCEVDIDNCQSHQCANGATCISHTNG-----YSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 1289 VARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGG 1348
L C G C + +C C PG +G C CA+ PC++GG
Sbjct: 1259 CGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEK--------DIDECASDPCVNGG 1310
Query: 1349 SCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSE 1383
C+ L F+C C + G RCE A +S+
Sbjct: 1311 LCQD--LLNKFQCLCDVAFAGERCEVDLADDLISD 1343
Score = 77.4 bits (189), Expect = 2e-13
Identities = 53/190 (27%), Positives = 73/190 (38%), Gaps = 18/190 (9%)
Query: 1206 INECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSP 1265
+N C S C H +C +D + C C G+SG C+ + C S PC HG C
Sbjct: 1140 LNVCNSNPC--LHGGNC-EDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRV 1195
Query: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325
+ C C + G CE +C+ QC G C G C C +G CR
Sbjct: 1196 A-----AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Query: 1326 S--FPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSE 1383
P + G + C +GG+C +C C G+TG CE E +
Sbjct: 1251 QSRLPSTVCGNEKTNLT---CYNGGNC--TEFQTELKCMCRPGFTGEWCEKD--IDECAS 1303
Query: 1384 EPRCPRAACQ 1393
+P CQ
Sbjct: 1304 DPCVNGGLCQ 1313
Score = 68.2 bits (165), Expect = 9e-11
Identities = 30/69 (43%), Positives = 42/69 (60%), Gaps = 1/69 (1%)
Query: 471 DECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530
+ C+S+PC NGGVC R + FSC+CP+ SG C+ +V C +PC +GA+C G+E
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 531 CRCAEGFEG 539
C F G
Sbjct: 948 CIANAVFNG 956
Score = 58.5 bits (140), Expect = 7e-08
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 433 NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492
N C S PC N C R F+C C A +G CE ++ C SPC +G C+ + GF
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 493 CTCPSGFSGSTCQL 506
C + F+G + Q+
Sbjct: 948 CIANAVFNGQSGQI 961
Score = 55.5 bits (132), Expect = 6e-07
Identities = 21/52 (40%), Positives = 30/52 (57%)
Query: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
++C+S PC GG C S F C+CP G+ CE + C +PC HG +C+
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQ 940
Score = 53.5 bits (127), Expect = 2e-06
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 584 DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYD 642
+ C+S PC +GG C D + C CP+ T+G CE + C +PC G C+ + ++
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 643 CVCQPGFTG 651
C+ F G
Sbjct: 948 CIANAVFNG 956
Score = 51.2 bits (121), Expect = 1e-05
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCL 1023
C S PC +GGVC + F C+C +G C+ V WC PC +G +C V G C+
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECI 949
Query: 1024 CPPGWSGR 1031
++G+
Sbjct: 950 ANAVFNGQ 957
Score = 50.4 bits (119), Expect = 2e-05
Identities = 26/73 (35%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCT 987
C + C NGG C + FSC C P T E C PC HG C GF C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECI 949
Query: 988 CLESFTGPQCQTL 1000
F G Q L
Sbjct: 950 ANAVFNGQSGQIL 962
Score = 49.3 bits (116), Expect = 4e-05
Identities = 30/83 (36%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 72 VGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHG 131
V + C ++ C S PC GVC S FSC CP G C C SPC HG
Sbjct: 881 VTQGCAGDNSCKSNPCHNGGVCHSR----WDDFSCSCPALTSGKACEEVQWCGFSPCPHG 936
Query: 132 ARCSVGPDGRFLCSCPPGYQGRS 154
A+C G F C + G+S
Sbjct: 937 AQCQPVLQG-FECIANAVFNGQS 958
Score = 47.4 bits (111), Expect = 2e-04
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 15/108 (13%)
Query: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
P+P N ++T CA G N C + C NGG C + ++C C
Sbjct: 866 PNPTNNASLNPVLVNVTQGCA------GDN------SCKSNPCHNGGVCHSRWDDFSCSC 913
Query: 263 PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES 310
P +G+ C E+V C P C +G C L G C+ + G+S
Sbjct: 914 PALTSGKAC-EEVQWCGFSP--CPHGAQCQPVLQGFECIANAVFNGQS 958
Score = 47.4 bits (111), Expect = 2e-04
Identities = 24/69 (34%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 851 NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT-CTDHVASFT 909
N C NPC NGG C FSCSC P + +V C +PC G C + F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSC-PALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 910 CTCPPGYGG 918
C + G
Sbjct: 948 CIANAVFNG 956
Score = 46.6 bits (109), Expect = 3e-04
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLC 1146
C + PC +GG C + C C +G CE +V C PC HG C ++ + C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
Score = 46.2 bits (108), Expect = 4e-04
Identities = 29/87 (33%), Positives = 34/87 (39%), Gaps = 14/87 (16%)
Query: 1113 GYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS 1172
G GDN C S PC +GG C + CSCP T G CE CG P
Sbjct: 884 GCAGDN------SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSP---- 932
Query: 1173 GPRCLHNGTCVDLVGGFRCTCPPGYTG 1199
C H C ++ GF C + G
Sbjct: 933 ---CPHGAQCQPVLQGFECIANAVFNG 956
Score = 45.8 bits (107), Expect = 5e-04
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 153 RSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212
+ C D + C+ PC +GG C + F C CPA +G CE C SPC +G C
Sbjct: 883 QGCAGD-NSCK-SNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQC 939
Query: 213 RQSGDLTYDCACLPGFEGQNCEV 235
Q ++C F GQ+ ++
Sbjct: 940 -QPVLQGFECIANAVFNGQSGQI 961
Score = 45.8 bits (107), Expect = 5e-04
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Query: 269 QFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT 328
Q C D + C+ P CHNGG C + SC C +G++C + + C + C HGA
Sbjct: 883 QGCAGD-NSCKSNP--CHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQ 938
Query: 329 CHDRVASFYC 338
C + F C
Sbjct: 939 CQPVLQGFEC 948
Score = 45.4 bits (106), Expect = 6e-04
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
C D++C SNPCH +C + + C+CP +G AC ++V C G +PC H +C
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDD--FSCSCPALTSGKAC-EEVQWC--GFSPCPHGAQC 939
Query: 409 VNTQGSFLCQCGRGYTG 425
F C + G
Sbjct: 940 QPVLQGFECIANAVFNG 956
Score = 45.4 bits (106), Expect = 6e-04
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 547 DDCSPDPCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
+ C +PCH+G C FSC+C +G CE +V C PC HG +C ++ +
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 606 C 606
C
Sbjct: 948 C 948
Score = 45.1 bits (105), Expect = 8e-04
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 884 CARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDG 942
CA D + C SNPC G C F+C+CP G CE ++ C S C +G C
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPV 942
Query: 943 VNSFSCLCRPGYTG 956
+ F C+ + G
Sbjct: 943 LQGFECIANAVFNG 956
Score = 45.1 bits (105), Expect = 8e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFS 567
+ C S PC NG C + D + C C G C+ V C PC HG +C + F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 568 CACAPGYTG 576
C + G
Sbjct: 948 CIANAVFNG 956
Score = 45.1 bits (105), Expect = 8e-04
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 659 NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI-CYDAPGGFR 717
N C S+PC GG C + F C CP + C C PC HG C GF
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 718 CVCEPGWSG 726
C+ ++G
Sbjct: 948 CIANAVFNG 956
Score = 45.1 bits (105), Expect = 8e-04
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 622 DDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFR 680
+ C SNPC GVC + + C C +G C E+ C SPC G C GF
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 681 CL 682
C+
Sbjct: 948 CI 949
Score = 45.1 bits (105), Expect = 8e-04
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
C GG C C CP +G CE EV C PC HG C+ + G+ C +
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 1115 NGDN 1118
NG +
Sbjct: 955 NGQS 958
Score = 44.7 bits (104), Expect = 0.001
Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLN 176
C+ + C S+PC +G C D F CSCP G++C +V C PC HG C
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDD-FSCSCPALTSGKAC-EEVQWCGF-SPCPHGAQCQP 941
Query: 177 TPGSFRCQCPAGYTG 191
F C A + G
Sbjct: 942 VLQGFECIANAVFNG 956
Score = 44.3 bits (103), Expect = 0.001
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 5/95 (5%)
Query: 369 NPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRC 428
NP N ++ T G + S +NPC + G C + F C C +G C
Sbjct: 867 NPTNNASLNPVLVNVTQGCAGDN----SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC 922
Query: 429 ETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTG 463
E +V C PC + A C + F CI A F G
Sbjct: 923 E-EVQWCGFSPCPHGAQCQPVLQGFECIANAVFNG 956
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGI-CTNLAGSF 833
C NPC +GG C S CSCP G C ++V C G +PC PHG C + F
Sbjct: 891 CKSNPCHNGGVCHSRWDDFS-CSCPALTSGKAC-EEVQWC-GFSPC-PHGAQCQPVLQGF 946
Query: 834 SCTCHGGYTGPS 845
C + + G S
Sbjct: 947 ECIANAVFNGQS 958
Score = 42.7 bits (99), Expect = 0.004
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG 878
PC G+C + FSC+C +G +C +++ C +PC +G CQ + F C
Sbjct: 895 PCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFECIANAV 953
Query: 879 FAG 881
F G
Sbjct: 954 FNG 956
Score = 42.0 bits (97), Expect = 0.007
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 11/65 (16%)
Query: 1202 CEADINECRSGACH---AAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHG 1258
C D N C+S CH H+R F C C A SG C+ V C PC HG
Sbjct: 885 CAGD-NSCKSNPCHNGGVCHSR------WDDFSCSCPALTSGKACEEV-QWCGFSPCPHG 936
Query: 1259 GQCRP 1263
QC+P
Sbjct: 937 AQCQP 941
Score = 40.8 bits (94), Expect = 0.016
Identities = 17/51 (33%), Positives = 23/51 (45%)
Query: 316 DDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 366
+ C + C +G CH R F C+CP +G C C +PC A C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
Score = 40.0 bits (92), Expect = 0.027
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 6/74 (8%)
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
C+S PC +GG C F+C C G CE V + C CP G CQ +
Sbjct: 891 CKSNPCHNGGVCHSRWDD-----FSCSCPALTSGKACEEV-QWCGFSPCPHGAQCQPVLQ 944
Query: 1310 GPRCACPPGLSGPS 1323
G C +G S
Sbjct: 945 GFECIANAVFNGQS 958
Score = 39.3 bits (90), Expect = 0.045
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 399 ANPCEHLGRCVNTQGSFLCQCGRGYTGPRC 428
+ PC+ GRC+N S+ C C R Y GP C
Sbjct: 678 SQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 38.1 bits (87), Expect = 0.10
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRCLC 1234
C + G C F C+CP +G CE ++ C C H A + LQ GF C+
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ----GFECIA 950
Query: 1235 HAGFSG 1240
+A F+G
Sbjct: 951 NAVFNG 956
Score = 37.7 bits (86), Expect = 0.13
Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 5/39 (12%)
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCER 1288
CESQPCQ G+C L++ C C +P+ GP C R
Sbjct: 676 CESQPCQSRGRC-----INLWLSYQCDCHRPYEGPNCLR 709
Score = 37.4 bits (85), Expect = 0.17
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFH 757
C PC +G +C+ F C C SG C + C PC G C GF
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV---QWCGFSPCPHGAQCQPVLQGFE 947
Query: 758 CTCPPGVQGRQCELL 772
C G+ ++L
Sbjct: 948 CIANAVFNGQSGQIL 962
Score = 37.0 bits (84), Expect = 0.23
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 584 DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNC 617
D C SQPC+ G+C++L Y C C G NC
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 37.0 bits (84), Expect = 0.23
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 1086 DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
D C +QPCQ G C Y C+C Y G NC
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 37.0 bits (84), Expect = 0.23
Identities = 14/28 (50%), Positives = 16/28 (57%)
Query: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSC 846
PC G C NL S+ C CH Y GP+C
Sbjct: 680 PCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 35.8 bits (81), Expect = 0.50
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 735 RDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC 769
+D CESQPC++ G C + + + C C +G C
Sbjct: 673 KDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 35.4 bits (80), Expect = 0.66
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 5/96 (5%)
Query: 19 PPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQL 78
P P +L +L+ G A +PC NGG C + +C CP G+ C+
Sbjct: 866 PNPTNNASLNPVLVNVTQGCAGDNSCKSNPCHNGGVCHSRWD-DFSCSCPALTSGKACEE 924
Query: 79 EDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRG 114
C PC CQ V+ G F C F G
Sbjct: 925 VQWCGFSPCPHGAQCQ-PVLQG---FECIANAVFNG 956
Score = 35.0 bits (79), Expect = 0.86
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 1124 DECASQPCQHGGSCIDLVARYLCSC 1148
D C SQPCQ G CI+L Y C C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDC 698
Score = 35.0 bits (79), Expect = 0.86
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 9/61 (14%)
Query: 1292 SCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCR 1351
SC+ C G C C+CP SG +C C +PC HG C+
Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQW---------CGFSPCPHGAQCQ 940
Query: 1352 P 1352
P
Sbjct: 941 P 941
Score = 34.3 bits (77), Expect = 1.5
Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
C +D C S PC RG C + ++ + C C R + GP+C
Sbjct: 670 CVRKDWCESQPCQSRGRCINLWLS----YQCDCHRPYEGPNC 707
Score = 33.9 bits (76), Expect = 1.9
Identities = 13/36 (36%), Positives = 20/36 (55%)
Query: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544
D C S PC++ +C++ Y+C C +EG C R
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLR 709
Score = 33.9 bits (76), Expect = 1.9
Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%)
Query: 1002 DWCSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLC 1033
DWC QPCQ+ GRC+ C C + G C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 33.5 bits (75), Expect = 2.5
Identities = 12/29 (41%), Positives = 17/29 (58%)
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLC 194
+PC+ G C+N S++C C Y GP C
Sbjct: 679 QPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (72), Expect = 5.6
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
C+ PC + G C + S+ C C + GP C R+
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 336 bits (862), Expect = 1e-91
Identities = 201/618 (32%), Positives = 260/618 (42%), Gaps = 97/618 (15%)
Query: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQG 413
AC S+PC C G TC P G Q PC H CV QG
Sbjct: 41 ACASDPCAPGTECQATESGGY---TCGPMEPRGCATQ----------PCHHGALCV-PQG 86
Query: 414 ----SFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVD 469
F C C G+ GPRCE D++EC S PC + ATC + ++ C C G+ G CE++
Sbjct: 87 PDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEME 146
Query: 470 IDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGY 529
+DEC S+PC++GG C D V F C C G+ G+ CQLD+DEC S PC +G C D +G+
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGF 206
Query: 530 ECRCA-EGFEGTLCDRNVDDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECR 587
C CA G+EGT C+R V +C+ PC H+ C++G+ SF C C PGY+G CE DEC
Sbjct: 207 RCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECA 266
Query: 588 SQPCRHGGKCLDLVDK---------------------YLCRCPSGTTGVNCEVNIDDCAS 626
S PC+HGG+CL D +LC CP G G +C V +D+CAS
Sbjct: 267 SSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECAS 326
Query: 627 NPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPP 685
PC G C+D N + C C G+ GP C +++EC S PC GG+C D G+ C CP
Sbjct: 327 RPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPE 386
Query: 686 -----GSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACES 740
L H C I + C C PG GP C Q+
Sbjct: 387 TWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAG 446
Query: 741 QPCRA---GGTCSSDGMGFHCTCPPGVQGR-----------------QCELLSPCT---- 776
P +A G + F T P G Q L S T
Sbjct: 447 SPIQASVPAGGPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLV 506
Query: 777 ---PNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSF 833
P+ + G L + + C + +GP T L
Sbjct: 507 LRLPDLALNDGHWHQVEVVLHLATLELRLWHEGCPARLCVASGPVALASTASATPLPAGI 566
Query: 834 SCTCHGGYTGPSCDQDI-----------------------NDCDPNPCLNGGSCQDGVGS 870
S G T C QD+ C P PC++GGSC D
Sbjct: 567 SSAQLGDATFAGCLQDVRVDGHLLLPEDLGENVLLGCERREQCRPLPCVHGGSCVDLWTH 626
Query: 871 FSCSCLPGFAGPRCARDV 888
F C C GP CA ++
Sbjct: 627 FRCDCARPHRGPTCADEI 644
Score = 300 bits (769), Expect = 8e-81
Identities = 168/495 (33%), Positives = 212/495 (42%), Gaps = 88/495 (17%)
Query: 737 ACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVC 796
AC S PC G C + G + P +G C PC HG C
Sbjct: 41 ACASDPCAPGTECQATESGGYTCGPMEPRG--------CATQPCHHGALC---------- 82
Query: 797 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN 856
PQG P P G F C C G+ GP C+ DI++C
Sbjct: 83 -VPQG---------------PDPTG-----------FRCYCVPGFQGPRCELDIDECASR 115
Query: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPG 915
PC +G +C++ + C C G+AG C +VDEC S PC G+C D V SF C C PG
Sbjct: 116 PCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPG 175
Query: 916 YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCR-PGYTGAHCQHEADPCLSRPCLHG 974
YGG C+ DL +C C +GGTC D VN F C C GY G HC+ E C S PC H
Sbjct: 176 YGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHN 235
Query: 975 GVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ----------------- 1017
C FRC C ++G C+ D C+ PCQ+GGRC+Q
Sbjct: 236 ASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGA 295
Query: 1018 ------TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1071
G C CPPG+ G C + C C GG C D + C
Sbjct: 296 FSFRHAAGFLCHCPPGFEGADCGVEVDECASRP----------CLNGGHCQDLPNGFQCH 345
Query: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC 1131
CP+G G CE++VD CL+ PC HGGTC + GY+C C + G +C + C C
Sbjct: 346 CPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTC 405
Query: 1132 QHGGSCIDL----VARYLCSCPPGTLGVLCEINED-DCGPGPPLDSGPRCLHNGTCVDLV 1186
+CI + V Y+C CPPGT G C N G P+ + + G + L
Sbjct: 406 PLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQAS---VPAGGPLGLA 462
Query: 1187 GGFRCTCPPGYTGLR 1201
FR T P G R
Sbjct: 463 LRFRTTLPAGTLATR 477
Score = 300 bits (768), Expect = 1e-80
Identities = 156/408 (38%), Positives = 197/408 (48%), Gaps = 49/408 (12%)
Query: 661 CASSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDA---PGG 715
CAS PC G C E+G + C G + P CA +PC HG +C P G
Sbjct: 42 CASDPCAPGTECQATESGGYTC----GPMEP------RGCATQPCHHGALCVPQGPDPTG 91
Query: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSP 774
FRC C PG+ GPRC + D C S+PC G TC + + C CP G G CE+ +
Sbjct: 92 FRCYCVPGFQGPRCELDI--DECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDE 149
Query: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFS 834
C PC HGG C G C C G+ G RCQ D+DEC PC G C +L F
Sbjct: 150 CASAPCLHGGSCLDGVGSFR-CVCAPGYGGTRCQLDLDECQSQ-PCAHGGTCHDLVNGFR 207
Query: 835 CTCHG-GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLS 893
C C G GY G C++++ +C PC + SC +G+GSF C C PG++G C D DEC S
Sbjct: 208 CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267
Query: 894 NPCGPG-TCTD---------------------HVASFTCTCPPGYGGFHCEQDLPDCSPS 931
+PC G C H A F C CPPG+ G C ++ +C+
Sbjct: 268 SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASR 327
Query: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
C NGG C D N F C C GY G C+ + D CLS PCLHGG CS G+ C C E+
Sbjct: 328 PCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPET 387
Query: 992 FTGPQCQTLVDWCSRQPCQNGGRCV---QTGAY---CLCPPGWSGRLC 1033
+ G C + C C C+ ++G + C CPPG G C
Sbjct: 388 WGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 298 bits (764), Expect = 3e-80
Identities = 152/413 (36%), Positives = 201/413 (48%), Gaps = 44/413 (10%)
Query: 120 PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-- 177
P C S PCA G C G + C + R C + +PC HG C+
Sbjct: 39 PSACASDPCAPGTECQATESGGYTCG---PMEPRGCAT--------QPCHHGALCVPQGP 87
Query: 178 -PGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN 236
P FRC C G+ GP CE CA PC +G TCR D Y+C C G+ G CE+
Sbjct: 88 DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLAD-RYECHCPLGYAGVTCEME 146
Query: 237 VDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
VD+C CL+GG+C+DGV ++ C C P + G C D+DECQ QP C +GGTC + +
Sbjct: 147 VDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVN 204
Query: 297 GHSCVCV-NGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DA 354
G C C G+ G C + + +CA+A C H A+C + + SF C C G +G LC +D D
Sbjct: 205 GFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDE 264
Query: 355 CVSNPCHEDAIC--DTNPV-----------------NGRAICTCPPGFTGGACDQDVDEC 395
C S+PC C ++P +C CPPGF G C +VDEC
Sbjct: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDEC 324
Query: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
+ + PC + G C + F C C GY GP CE DV+ECLS PC + TC D + + C
Sbjct: 325 A--SRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYIC 382
Query: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVC----KDRVNGFSCTCPSGFSGSTC 504
C + G C V + CQ C C + V+ + C CP G G C
Sbjct: 383 RCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 283 bits (723), Expect = 2e-75
Identities = 149/411 (36%), Positives = 191/411 (46%), Gaps = 66/411 (16%)
Query: 539 GTLCDRNVDDCSPD-----------------------------PCHHGR-CV---DGIAS 565
GT+ C+ D PCHHG CV
Sbjct: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTG 91
Query: 566 FSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCA 625
F C C PG+ G RCE +DEC S+PC HG C +L D+Y C CP G GV CE+ +D+CA
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 626 SNPCTF-GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCP 684
S PC G C DG+ + CVC PG+ G C ++++EC S PC GG+C D NGFRC C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 685 -PGSLPPLCLPPSHPCAHEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP 742
G C CA PC H C + G FRC+C PG+SG C + D C S P
Sbjct: 212 GTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELC--EVDEDECASSP 269
Query: 743 CRAGGTC--SSD-------------------GMGFHCTCPPGVQGRQCEL-LSPCTPNPC 780
C+ GG C SD GF C CPPG +G C + + C PC
Sbjct: 270 CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRPC 329
Query: 781 EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG 840
+GG C+ P C CP G+ GP C++DVDEC PC G C++ + C C
Sbjct: 330 LNGGHCQDLPNGFQ-CHCPDGYAGPTCEEDVDECLSD-PCLHGGTCSDTVAGYICRCPET 387
Query: 841 YTGPSCDQDINDCDPNPCLNGGSC----QDGVGSFSCSCLPGFAGPRCARD 887
+ G C + C + C +C + GV S+ C C PG GP C ++
Sbjct: 388 WGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 270 bits (691), Expect = 9e-72
Identities = 143/434 (32%), Positives = 202/434 (46%), Gaps = 66/434 (15%)
Query: 925 LPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP--CLSRPCLHGGVCSAAHP 982
+P PS+C + C G C+ +G + +P C ++PC HG +C P
Sbjct: 34 VPSEPPSACASD-PCAPGTE-----CQATESGGYTCGPMEPRGCATQPCHHGALCVPQGP 87
Query: 983 ---GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCPPGWSGRLCDIRS 1037
GFRC C+ F GP+C+ +D C+ +PC +G C + C CP G++G C++
Sbjct: 88 DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
Query: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGG 1097
C A C GG C+D S CVC G G+ C+ ++D C +QPC HGG
Sbjct: 148 DECASAP----------CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGG 197
Query: 1098 TCRGYMGGYMCECL-PGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVL 1156
TC + G+ C+C GY G +CE +V ECAS PC+H SC++ + + C C PG G L
Sbjct: 198 TCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGEL 257
Query: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDL---------------------VGGFRCTCPP 1195
CE++ED+C P C H G C+ GF C CPP
Sbjct: 258 CEVDEDECASSP-------CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPP 310
Query: 1196 GYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP 1254
G+ G C +++EC S C + H QD GF+C C G++GP C+ + C S P
Sbjct: 311 GFEGADCGVEVDECASRPCLNGGHC----QDLPNGFQCHCPDGYAGPTCEEDVDECLSDP 366
Query: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC----QQTPRG 1310
C HGG C + + C C + + G C C+ CP+ C +
Sbjct: 367 CLHGGTCSDTVAG-----YICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHS 421
Query: 1311 PRCACPPGLSGPSC 1324
C CPPG GP C
Sbjct: 422 YVCHCPPGTHGPFC 435
Score = 263 bits (672), Expect = 1e-69
Identities = 152/449 (33%), Positives = 198/449 (44%), Gaps = 62/449 (13%)
Query: 853 CDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT-CTDH---VAS 907
C +PC G CQ G ++C GP R C + PC G C
Sbjct: 42 CASDPCAPGTECQATESGGYTC-------GPMEPRG---CATQPCHHGALCVPQGPDPTG 91
Query: 908 FTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCL 967
F C C PG+ G CE D+ +C+ C +G TC + + + C C GY G C+ E D C
Sbjct: 92 FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECA 151
Query: 968 SRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC--VQTGAYCLCP 1025
S PCLHGG C FRC C + G +CQ +D C QPC +GG C + G C C
Sbjct: 152 SAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCA 211
Query: 1026 -PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQE 1084
G+ G C+ L C A C+ C++ S C+C G +G CE +
Sbjct: 212 GTGYEGTHCEREVLECASAP----------CEHNASCLEGLGSFRCLCWPGYSGELCEVD 261
Query: 1085 VDPCLAQPCQHGGTCRG---------------------YMGGYMCECLPGYNGDNCEDDV 1123
D C + PCQHGG C + G++C C PG+ G +C +V
Sbjct: 262 EDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEV 321
Query: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
DECAS+PC +GG C DL + C CP G G CE + D+C P CLH GTC
Sbjct: 322 DECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP-------CLHGGTCS 374
Query: 1184 DLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPG-GGFRCLCHAGFSGPR 1242
D V G+ C CP + G C + C+ C A T + + G + C C G GP
Sbjct: 375 DTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPF 434
Query: 1243 C--QTVLSPCESQPCQHGGQCRPSPGPGG 1269
C T S P Q P+ GP G
Sbjct: 435 CGQNTTFSVMAGSPIQ---ASVPAGGPLG 460
Score = 261 bits (666), Expect = 7e-69
Identities = 148/407 (36%), Positives = 181/407 (44%), Gaps = 58/407 (14%)
Query: 1004 CSRQPCQNGGRC--VQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
C+ PC G C ++G Y P G + PC A LC G
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRG----CATQPCHHGA---------LCVPQGP- 87
Query: 1062 VDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED 1121
+ + C C G G CE ++D C ++PC HG TCR Y C C GY G CE
Sbjct: 88 --DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEM 145
Query: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT 1181
+VDECAS PC HGGSC+D V + C C PG G C+++ D+C P C H GT
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQP-------CAHGGT 198
Query: 1182 CVDLVGGFRCTCP-PGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSG 1240
C DLV GFRC C GY G CE ++ EC S C H CL+ G FRCLC G+SG
Sbjct: 199 CHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCE--HNASCLEGL-GSFRCLCWPGYSG 255
Query: 1241 PRCQTVLSPCESQPCQHGGQC--RPSPGPGGGLT--------------FTCHCAQPFWGP 1284
C+ C S PCQHGG+C R P GG+ F CHC F G
Sbjct: 256 ELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGA 315
Query: 1285 RCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPC 1344
C C C G CQ P G +C CP G +GP+C C + PC
Sbjct: 316 DCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEE--------DVDECLSDPC 367
Query: 1345 LHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAA 1391
LHGG+C + + C C + W G C + CP AA
Sbjct: 368 LHGGTC--SDTVAGYICRCPETWGGRDCSVQLTG---CQGHTCPLAA 409
Score = 249 bits (635), Expect = 3e-65
Identities = 153/433 (35%), Positives = 196/433 (45%), Gaps = 54/433 (12%)
Query: 28 PLLLLLAGPGAAAPPCLDGS-PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP 86
P L LLAG + PP S PCA G C S C G + R PCH G
Sbjct: 25 PALSLLAGTVPSEPPSACASDPCAPGTECQATESGGYTC----GPMEPRGCATQPCHHGA 80
Query: 87 -CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLC 144
C +G + F C C GF+GP C L D C S PC HGA C D R+ C
Sbjct: 81 LCVPQGPDPTG-------FRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLAD-RYEC 132
Query: 145 SCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPS 204
CP GY G +C +VDEC PC HGG+CL+ GSFRC C GY G C+ C
Sbjct: 133 HCPLGYAGVTCEMEVDEC-ASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQ 191
Query: 205 PCRNGGTCRQSGDLT--YDCACL-PGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQ 261
PC +GGTC DL + C C G+EG +CE V +C C + +C++G+ ++ C
Sbjct: 192 PCAHGGTCH---DLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCL 248
Query: 262 CPPEWTGQFCTEDVDECQLQPNACHNGGTC---------------------FNTLGGHSC 300
C P ++G+ C D DEC P C +GG C F G C
Sbjct: 249 CWPGYSGELCEVDEDECASSP--CQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLC 306
Query: 301 VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNP 359
C G+ G C +D+CA+ C +G C D F C CP G G C D D C+S+P
Sbjct: 307 HCPPGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDP 366
Query: 360 CHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCV----NTQGSF 415
C C ++ V G IC CP + G C + C + C C+ + S+
Sbjct: 367 CLHGGTC-SDTVAG-YICRCPETWGGRDCSVQLTGCQ--GHTCPLAATCIPIFESGVHSY 422
Query: 416 LCQCGRGYTGPRC 428
+C C G GP C
Sbjct: 423 VCHCPPGTHGPFC 435
Score = 181 bits (458), Expect = 1e-44
Identities = 101/297 (34%), Positives = 128/297 (43%), Gaps = 70/297 (23%)
Query: 39 AAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQ--- 94
A+ PCL G C +G + C+C PG+ G RCQL+ D C S PCA G C
Sbjct: 151 ASAPCLHGGSCLDGVGSFR-------CVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLV 203
Query: 95 --------------------------------SSVVAGTARFSCRCPRGFRGPDCSLP-D 121
+S + G F C C G+ G C + D
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDED 263
Query: 122 PCLSSPCAHGARCSVGPD--------------------GRFLCSCPPGYQGRSCRSDVDE 161
C SSPC HG RC D FLC CPPG++G C +VDE
Sbjct: 264 ECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDE 323
Query: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYD 221
C PC +GG C + P F+C CP GY GP CE C PC +GGTC + Y
Sbjct: 324 C-ASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTV-AGYI 381
Query: 222 CACLPGFEGQNCEVNVDDCPGHRCLNGGTCV----DGVNTYNCQCPPEWTGQFCTED 274
C C + G++C V + C GH C TC+ GV++Y C CPP G FC ++
Sbjct: 382 CRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQN 438
Score = 116 bits (291), Expect = 2e-25
Identities = 70/172 (40%), Positives = 80/172 (46%), Gaps = 19/172 (11%)
Query: 36 PGAAAP-------PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPC 87
PG AP P SPC + G C L AC C PGW G RC+ DPCHS PC
Sbjct: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDA-FACACGPGWEGPRCEAHVDPCHSAPC 1103
Query: 88 AGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDP----CLSSPCAHGARCSVGPDGRFL 143
A RG C + RF CRCP GF GP C LP P L+ C G+ C G
Sbjct: 1104 A-RGRCHTHP---DGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAA-N 1158
Query: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE 195
CSC G G+ C+ C PC +GGTC G C C A ++G CE
Sbjct: 1159 CSCLEGLAGQRCQVPTLPCE-ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 112 bits (281), Expect = 3e-24
Identities = 59/153 (38%), Positives = 76/153 (49%), Gaps = 8/153 (5%)
Query: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFR 182
C SPC H C D F C+C PG++G C + VD C PC G + G F
Sbjct: 1060 CAPSPCLHDGACRDLFDA-FACACGPGWEGPRCEAHVDPCH-SAPCARGRCHTHPDGRFE 1117
Query: 183 CQCPAGYTGPLCENPAVP---CAPS-PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVD 238
C+CP G+ GP C P VP C+ + C +G C + G +C+CL G GQ C+V
Sbjct: 1118 CRCPPGFGGPRCRLP-VPSKECSLNVTCLDGSPC-EGGSPAANCSCLEGLAGQRCQVPTL 1175
Query: 239 DCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
C + CLNGGTC C C ++GQFC
Sbjct: 1176 PCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 110 bits (274), Expect = 2e-23
Identities = 57/151 (37%), Positives = 71/151 (47%), Gaps = 9/151 (5%)
Query: 586 CRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCR---DGINRYD 642
C PC H G C DL D + C C G G CE ++D C S PC G C DG R++
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDG--RFE 1117
Query: 643 CVCQPGFTGPLCNVEI--NECA-SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC 699
C C PGF GP C + + EC+ + C +G C G C C G C P+ PC
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 700 AHEPC-SHGICYDAPGGFRCVCEPGWSGPRC 729
PC + G C A G C+C +SG C
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 108 bits (270), Expect = 6e-23
Identities = 57/152 (37%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
Query: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG-YEC 531
C SPC++ G C+D + F+C C G+ G C+ VD C S PC G +C PDG +EC
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 532 RCAEGFEGTLCDRNV--DDCSPD-PCHHGR-CVDGIASFSCACAPGYTGTRCESQVDECR 587
RC GF G C V +CS + C G C G + +C+C G G RC+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 588 SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEV 619
+ PC +GG C C C + +G CEV
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 106 bits (264), Expect = 3e-22
Identities = 64/185 (34%), Positives = 75/185 (40%), Gaps = 12/185 (6%)
Query: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDP 1226
G P+ + CLH+G C DL F C C PG+ G RCEA ++ C S C C P
Sbjct: 1056 GAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR---CHTHP 1112
Query: 1227 GGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRP-SPGPGGGLTFTCHCAQPFWGPR 1285
G F C C GF GPRC+ P S+ C C SP GG C C + G R
Sbjct: 1113 DGRFECRCPPGFGGPRCRL---PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 1286 CERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSP-----PGASNASCA 1340
C+ C C G C+ C C SG C G P P A A
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLPLPLPFPLLEVAVPA 1229
Query: 1341 AAPCL 1345
A CL
Sbjct: 1230 ACACL 1234
Score = 104 bits (260), Expect = 9e-22
Identities = 51/147 (34%), Positives = 69/147 (46%), Gaps = 3/147 (2%)
Query: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMA 459
+PC H G C + +F C CG G+ GPRCE V+ C S PC G+F C C
Sbjct: 1063 SPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCPP 1122
Query: 460 GFTGTYCEVDI--DECQ-SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPC 516
GF G C + + EC + C++G C+ +C+C G +G CQ+ C + PC
Sbjct: 1123 GFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC 1182
Query: 517 RNGAKCVDQPDGYECRCAEGFEGTLCD 543
NG C EC C F G C+
Sbjct: 1183 LNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 104 bits (259), Expect = 1e-21
Identities = 57/161 (35%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ--TGA 1020
A C PCLH G C F C C + GP+C+ VD C PC G RC G
Sbjct: 1057 APVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGR 1115
Query: 1021 Y-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGS 1079
+ C CPPG+ G C + +P +E + + C G C + C C EG G
Sbjct: 1116 FECRCPPGFGGPRCRL-PVPSKECSLNV------TCLDGSPCEGGSPAANCSCLEGLAGQ 1168
Query: 1080 HCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE 1120
C+ PC A PC +GGTCR G C C ++G CE
Sbjct: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 103 bits (258), Expect = 2e-21
Identities = 53/151 (35%), Positives = 71/151 (47%), Gaps = 5/151 (3%)
Query: 814 CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC 873
CA P+PC G C +L +F+C C G+ GP C+ ++ C PC G G F C
Sbjct: 1060 CA-PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
Query: 874 SCLPGFAGPRCARDV--DEC-LSNPCGPGT-CTDHVASFTCTCPPGYGGFHCEQDLPDCS 929
C PGF GPRC V EC L+ C G+ C + C+C G G C+ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
+ C NGGTC C+C ++G C+
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 103 bits (257), Expect = 2e-21
Identities = 65/170 (38%), Positives = 76/170 (44%), Gaps = 12/170 (7%)
Query: 685 PGSLPPLCLPPSHP-CAHEPCSH-GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQP 742
PG+ P+ P CA PC H G C D F C C PGW GPRC + D C S P
Sbjct: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHV--DPCHSAP 1102
Query: 743 CRAGGTCSSDGMG-FHCTCPPGVQGRQCELLSP---CTPN-PCEHGGRCESAPGQLPVCS 797
C A G C + G F C CPPG G +C L P C+ N C G CE CS
Sbjct: 1103 C-ARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGG-SPAANCS 1160
Query: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
C +G G RCQ C PC G C G C C+ ++G C+
Sbjct: 1161 CLEGLAGQRCQVPTLPCEA-NPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 103 bits (257), Expect = 2e-21
Identities = 54/150 (36%), Positives = 69/150 (46%), Gaps = 4/150 (2%)
Query: 738 CESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVC 796
C PC G C F C C PG +G +CE + PC PC G RC + P C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 797 SCPQGWQGPRCQQDVD--ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
CP G+ GPRC+ V EC+ C C + + +C+C G G C C+
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRC 884
NPCLNGG+C+ G C C F+G C
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 103 bits (256), Expect = 3e-21
Identities = 56/171 (32%), Positives = 73/171 (42%), Gaps = 8/171 (4%)
Query: 877 PGFAGPRCA-RDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCF 934
PG P R C +PC G C D +F C C PG+ G CE + C + C
Sbjct: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCA 1104
Query: 935 NGGTCVDGVNSFSCLCRPGYTGAHCQ---HEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
G F C C PG+ G C+ + L+ CL G C P C+CLE
Sbjct: 1105 RGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEG 1164
Query: 992 FTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPGWSGRLCDI-RSLP 1039
G +CQ C PC NGG C G C+C +SG+ C++ + LP
Sbjct: 1165 LAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGLP 1215
Score = 100 bits (250), Expect = 1e-20
Identities = 56/153 (36%), Positives = 72/153 (47%), Gaps = 7/153 (4%)
Query: 624 CASNPCTF-GVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCL 682
CA +PC G CRD + + C C PG+ GP C ++ C S+PC G + F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 683 CPPGSLPPLC-LP-PSHPCA-HEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLARDAC 738
CPPG P C LP PS C+ + C G C C C G +G RC + C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRC--QVPTLPC 1177
Query: 739 ESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL 771
E+ PC GGTC + G C C G+ CE+
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 99.0 bits (245), Expect = 5e-20
Identities = 54/162 (33%), Positives = 75/162 (46%), Gaps = 9/162 (5%)
Query: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
C C +PC D C + C C PG+ G C+ VD C + PC GRC
Sbjct: 1054 CRGAPVCAPSPCLHDGAC--RDLFDAFACACGPGWEGPRCEAHVDPCH--SAPCAR-GRC 1108
Query: 409 -VNTQGSFLCQCGRGYTGPRCETDV--NEC-LSGPCRNQATCLDRIGQFTCICMAGFTGT 464
+ G F C+C G+ GPRC V EC L+ C + + C C C+ G G
Sbjct: 1109 HTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQ 1168
Query: 465 YCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL 506
C+V C+++PC+NGG C+ C C + FSG C++
Sbjct: 1169 RCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 98.2 bits (243), Expect = 8e-20
Identities = 52/153 (33%), Positives = 68/153 (44%), Gaps = 10/153 (6%)
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNG-FSC 493
C PC + C D F C C G+ G CE +D C S+PC G C +G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGRFEC 1118
Query: 494 TCPSGFSGSTCQLDV--DECA-STPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCS 550
CP GF G C+L V EC+ + C +G+ C C C EG G C C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 551 PDPCHHG---RCVDGIASFSCACAPGYTGTRCE 580
+PC +G R G++ C C ++G CE
Sbjct: 1179 ANPCLNGGTCRAAGGVS--ECICNARFSGQFCE 1209
Score = 97.8 bits (242), Expect = 1e-19
Identities = 60/185 (32%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 903 DHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
+H AS+ T P G C + P C+PS C + G C D ++F+C C PG+ G C+
Sbjct: 1039 EHFASWPGTPAPILG---C-RGAPVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAH 1094
Query: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLV--DWCS-RQPCQNGGRCV--Q 1017
DPC S PC G + F C C F GP+C+ V CS C +G C
Sbjct: 1095 VDPCHSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGS 1154
Query: 1018 TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT 1077
A C C G +G+ C + +LPC C GG C C+C +
Sbjct: 1155 PAANCSCLEGLAGQRCQVPTLPCE----------ANPCLNGGTCRAAGGVSECICNARFS 1204
Query: 1078 GSHCE 1082
G CE
Sbjct: 1205 GQFCE 1209
Score = 96.7 bits (239), Expect = 2e-19
Identities = 51/157 (32%), Positives = 62/157 (39%), Gaps = 7/157 (4%)
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
C PC H G CR + C C PG+ G CE VD C S PC G R+ C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
CPPG G C + P CL C C+C G G RC+
Sbjct: 1120 CPPGFGGPRCRLPV----PSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTL 1175
Query: 1208 ECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQ 1244
C + C T + GG C+C+A FSG C+
Sbjct: 1176 PCEANPCLNGGT---CRAAGGVSECICNARFSGQFCE 1209
Score = 95.1 bits (235), Expect = 7e-19
Identities = 51/153 (33%), Positives = 65/153 (42%), Gaps = 4/153 (2%)
Query: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
CAPSPC + G CR D + CAC PG+EG CE +VD C C G + C
Sbjct: 1060 CAPSPCLHDGACRDLFD-AFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFEC 1118
Query: 261 QCPPEWTGQFCTEDVD--ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318
+CPP + G C V EC L C +G C +C C+ G G+ C C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVT-CLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHL 351
C +G TC C C +G C +
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 82.4 bits (202), Expect = 5e-15
Identities = 160/658 (24%), Positives = 204/658 (31%), Gaps = 157/658 (23%)
Query: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAH------ 981
C P C +GG+CVD F C C + G C AD + GG S+A
Sbjct: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC---ADEIPAATFGLGGAPSSASFLLQEL 665
Query: 982 PGFRCTC------------LESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPG-W 1028
PG T L F L + S + R G+ + PG W
Sbjct: 666 PGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLS----EGRIRAEVPGSPAVVLPGRW 721
Query: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV--D 1086
L + L Q L Q GG+ + DS P G C Q++ D
Sbjct: 722 DDGLRHLVMLSFGPDQLQ---DLGQHVHVGGRLLAADSQ-----PWGGPFRGCLQDLRLD 773
Query: 1087 PC-----------LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGG 1135
C +QP + GG + C + D C+ PC +GG
Sbjct: 774 GCHLPFFPLPLDNSSQPSELGGRQSWNLTA------------GCVSE-DMCSPDPCFNGG 820
Query: 1136 SCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTC-- 1193
+C+ + C+CP G C + PG P CL TC ++ GF C
Sbjct: 821 TCLVTWNDFHCTCPANFTGPTCA--QQLWCPGQP------CLPPATCEEVPDGFVCVAEA 872
Query: 1194 ------PPGYTGLRCEADINECRSGACHAAHTRDC----LQDPGGGFRCLCHAGFSGPRC 1243
P ++G A G A TRD L+ G + A +G
Sbjct: 873 TFREGPPAAFSGHN--ASSGRLLGGLSLAFRTRDSEAWLLRAAAGALEGVWLAVRNGSLA 930
Query: 1244 QTVLSPCESQPCQHG--GQCRPSPGP--GGGLTFTCHCAQPFWGPRCER----------- 1288
V HG G P PGP G A R
Sbjct: 931 GGVRGG-------HGLPGAVLPIPGPRVADGAWHRVRLAMERPAATTSRWLLWLDGAATP 983
Query: 1289 -----VARSCRELQCPVGVPCQQTPRGPRCACPPGLSG---PSCRSFPGSPPGASN---- 1336
+A LQ P V C L G P R PG+ PGA
Sbjct: 984 VALRGLASDLGFLQGPGAVRILLAENFTGCLGRVALGGLPLPLARPRPGAAPGAREHFAS 1043
Query: 1337 --------------ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVS 1382
CA +PCLH G+CR L F CAC GW GPRCEA +
Sbjct: 1044 WPGTPAPILGCRGAPVCAPSPCLHDGACRD--LFDAFACACGPGWEGPRCEAHV---DPC 1098
Query: 1383 EEPRCPRAACQAK---RGDQRCDRECNSPGCGW--DGGDCSLSV----------GDPWRQ 1427
C R C R + RC P C +CSL+V G P
Sbjct: 1099 HSAPCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAAN 1158
Query: 1428 CEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCD 1485
C L+ C P + C GG R V E C F+ C+
Sbjct: 1159 CSCLE-------GLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.1 bits (196), Expect = 2e-14
Identities = 50/153 (32%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 282 PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV-ASFYCAC 340
P+ C + G C + +C C GW G C ++D C +A C G CH F C C
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFECRC 1120
Query: 341 PMGKTGLLCHLDDACVSNPCHEDAIC-DTNPVNG---RAICTCPPGFTGGACDQDVDECS 396
P G G C L S C + C D +P G A C+C G G C C
Sbjct: 1121 PPGFGGPRCRL--PVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 429
ANPC + G C G C C ++G CE
Sbjct: 1179 --ANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 73.2 bits (178), Expect = 3e-12
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 8/154 (5%)
Query: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHS 299
C CL+ G C D + + C C P W G C VD C P C G + G
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAP--CARGRCHTHPDGRFE 1117
Query: 300 CVCVNGWTGESCSQNI--DDCATAV-CFHGATCHDRVASFYCACPMGKTGLLCHLDD-AC 355
C C G+ G C + +C+ V C G+ C + C+C G G C + C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 356 VSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD 389
+NPC C G + C C F+G C+
Sbjct: 1178 EANPCLNGGTC--RAAGGVSECICNARFSGQFCE 1209
Score = 63.9 bits (154), Expect = 2e-09
Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 19/146 (13%)
Query: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGP--RCETDVNECLSG--------PCRNQAT 445
S G + + LG+ V+ G L + + GP C D+ L G P N +
Sbjct: 732 SFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLR--LDGCHLPFFPLPLDNSSQ 789
Query: 446 CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQ 505
+ G+ + AG V D C PC NGG C N F CTCP+ F+G TC
Sbjct: 790 PSELGGRQSWNLTAGC------VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCA 843
Query: 506 LDVDECASTPCRNGAKCVDQPDGYEC 531
+ C PC A C + PDG+ C
Sbjct: 844 QQL-WCPGQPCLPPATCEEVPDGFVC 868
Score = 60.8 bits (146), Expect = 1e-08
Identities = 73/276 (26%), Positives = 97/276 (35%), Gaps = 40/276 (14%)
Query: 660 ECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCV 719
+C PC GGSCVD FRC C P C P + AP +
Sbjct: 608 QCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI------PAATFGLGGAPSSASFL 661
Query: 720 CEPGWSGPRCSQSLARDACES--------QPCRAG-------GTCSSDGMGFHCTCPPGV 764
+ GP + S ES AG G ++ G PG
Sbjct: 662 LQE-LPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGR 720
Query: 765 --QGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGP--RCQQDV--DECA--- 815
G + ++ P+ + G+ G+L + + Q W GP C QD+ D C
Sbjct: 721 WDDGLRHLVMLSFGPDQLQDLGQHVHVGGRL-LAADSQPWGGPFRGCLQDLRLDGCHLPF 779
Query: 816 GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSC 875
P P + L G S G C P+PC NGG+C F C+C
Sbjct: 780 FPLPLDNSSQPSELGGRQSWNLTAGCVSEDM------CSPDPCFNGGTCLVTWNDFHCTC 833
Query: 876 LPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTC 910
F GP CA+ + C PC P TC + F C
Sbjct: 834 PANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVC 868
Score = 56.2 bits (134), Expect = 4e-07
Identities = 59/203 (29%), Positives = 68/203 (33%), Gaps = 32/203 (15%)
Query: 1262 RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSG 1321
RP PG F P C R A C C C+ CAC PG G
Sbjct: 1030 RPGAAPGAREHFASWPGTPAPILGC-RGAPVCAPSPCLHDGACRDLFDAFACACGPGWEG 1088
Query: 1322 PSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEV 1381
P C A C +APC G C P F C C G+ GPRC P + E
Sbjct: 1089 PRCE--------AHVDPCHSAPCAR-GRCHTHPDGR-FECRCPPGFGGPRCRLPVPSKEC 1138
Query: 1382 SEEPRC----------PRAACQAKRG--DQRCD---RECNSPGCGWDGGDCSLSVGDPWR 1426
S C P A C G QRC C + C +GG C + G
Sbjct: 1139 SLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPC-LNGGTCRAAGGVSEC 1197
Query: 1427 QCEALQCWRLFNNSRCDPACSSP 1449
C A F+ C+ A P
Sbjct: 1198 ICNA-----RFSGQFCEVAKGLP 1215
Score = 52.4 bits (124), Expect = 5e-06
Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD 217
+PC +GGTCL T F C CPA +TGP C + C PC TC + D
Sbjct: 814 DPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ-QLWCPGQPCLPPATCEEVPD 864
Score = 51.6 bits (122), Expect = 9e-06
Identities = 75/289 (25%), Positives = 93/289 (32%), Gaps = 85/289 (29%)
Query: 76 CQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS----------------- 118
C+ + C PC G C V F C C R RGP C+
Sbjct: 603 CERREQCRPLPCVHGGSC----VDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSA 658
Query: 119 ------LPDPCLSSPCAHGARCSVG-----------------PDGRFLCSCP-------P 148
LP P L+ R S G +GR P P
Sbjct: 659 SFLLQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLP 718
Query: 149 GYQGRSCRSDV------DECR-VGEPCRHGGTCLNTP-----GSFRCQCPAGYTGPLCEN 196
G R V D+ + +G+ GG L G FR C C
Sbjct: 719 GRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFR-GCLQDLRLDGCHL 777
Query: 197 PAVPC----APSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCV 252
P P + P GG RQS +LT C V+ D C C NGGTC+
Sbjct: 778 PFFPLPLDNSSQPSELGG--RQSWNLTAGC------------VSEDMCSPDPCFNGGTCL 823
Query: 253 DGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV 301
N ++C CP +TG C + + C QP C TC G CV
Sbjct: 824 VTWNDFHCTCPANFTGPTCAQQL-WCPGQP--CLPPATCEEVPDGFVCV 869
Score = 49.3 bits (116), Expect = 4e-05
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%)
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCT 494
C PC N TCL F C C A FTG C + C PC+ C++ +GF C
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Query: 495 C--------PSGFSG 501
P+ FSG
Sbjct: 870 AEATFREGPPAAFSG 884
Score = 48.9 bits (115), Expect = 6e-05
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 547 DDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
D CSPDPC +G C+ F C C +TG C Q+ C QPC C ++ D ++
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 606 C 606
C
Sbjct: 868 C 868
Score = 48.5 bits (114), Expect = 7e-05
Identities = 38/131 (29%), Positives = 48/131 (36%), Gaps = 28/131 (21%)
Query: 724 WSGP--RCSQSLARDACE-----------SQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE 770
W GP C Q L D C SQP GG S ++ T C
Sbjct: 759 WGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELGGRQS-----WNLTAG-------CV 806
Query: 771 LLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLA 830
C+P+PC +GG C C+CP + GP C Q + C G PC P C +
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFH-CTCPANFTGPTCAQQL-WCPG-QPCLPPATCEEVP 863
Query: 831 GSFSCTCHGGY 841
F C +
Sbjct: 864 DGFVCVAEATF 874
Score = 47.8 bits (112), Expect = 1e-04
Identities = 70/288 (24%), Positives = 89/288 (30%), Gaps = 61/288 (21%)
Query: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG---EPCRHGGT 173
C + C PC HG C V F C C ++G +C ++ G P
Sbjct: 603 CERREQCRPLPCVHGGSC-VDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFL 661
Query: 174 CLNTPG-------------------SFRCQCPAGYTGPLCEN------PAVPCAPSPCRN 208
PG F AG T L E P P P R
Sbjct: 662 LQELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRW 721
Query: 209 GGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTG 268
R L++ L GQ+ V G R L + W G
Sbjct: 722 DDGLRHLVMLSFGPDQLQDL-GQHVHV------GGRLLAADS-------------QPWGG 761
Query: 269 QF--CTEDV--DECQLQ--PNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV 322
F C +D+ D C L P N + LGG W + + D C+
Sbjct: 762 PFRGCLQDLRLDGCHLPFFPLPLDNSSQP-SELGGRQ-----SWNLTAGCVSEDMCSPDP 815
Query: 323 CFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNP 370
CF+G TC F+C CP TG C C PC A C+ P
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
Score = 47.8 bits (112), Expect = 1e-04
Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 2/62 (3%)
Query: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPC-SHGICYDAPGGFRCV 719
C+ PC GG+C+ N F C CP P C C +PC C + P GF CV
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVCV 869
Query: 720 CE 721
E
Sbjct: 870 AE 871
Score = 46.2 bits (108), Expect = 4e-04
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 384 TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQ 443
T G +D+ CS +PC + G C+ T F C C +TGP C + C PC
Sbjct: 802 TAGCVSEDM--CS--PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPP 856
Query: 444 ATCLDRIGQFTCICMAGF 461
ATC + F C+ A F
Sbjct: 857 ATCEEVPDGFVCVAEATF 874
Score = 44.3 bits (103), Expect = 0.001
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 619 VNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGEN 677
V+ D C+ +PC G C N + C C FTGP C ++ C PC +C + +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 678 GFRCL 682
GF C+
Sbjct: 865 GFVCV 869
Score = 43.9 bits (102), Expect = 0.002
Identities = 75/292 (25%), Positives = 96/292 (32%), Gaps = 40/292 (13%)
Query: 699 CAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM--- 754
C PC HG C D FRC C GP C+ D + GG SS
Sbjct: 609 CRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCA-----DEIPAATFGLGGAPSSASFLLQ 663
Query: 755 ---GFHCTCPPGVQGRQCELLSPCTPNPCEHG-------GRCESAPGQLPVCSCPQGWQG 804
G + T ++ R+ L N G GR + P P W
Sbjct: 664 ELPGPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDD 723
Query: 805 PRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGP--SCDQDI--NDCD----PN 856
+ V GP G ++ G + GP C QD+ + C P
Sbjct: 724 G-LRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFFPL 782
Query: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPG 915
P N + G S + G C + D C +PC GTC F CTCP
Sbjct: 783 PLDNSSQPSELGGRQSWNLTAG-----CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPAN 836
Query: 916 YGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLC----RPGYTGAHCQHEA 963
+ G C Q L C C TC + + F C+ R G A H A
Sbjct: 837 FTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNA 887
Score = 43.1 bits (100), Expect = 0.003
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 117 CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLN 176
C D C PC +G C V + F C+CP + G +C + G+PC TC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWND-FHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEE 861
Query: 177 TPGSFRCQCPAGY 189
P F C A +
Sbjct: 862 VPDGFVCVAEATF 874
Score = 41.6 bits (96), Expect = 0.009
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 579 CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDG 637
C S+ D C PC +GG CL + + C CP+ TG C + C PC C +
Sbjct: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEV 862
Query: 638 INRYDCVCQPGF 649
+ + CV + F
Sbjct: 863 PDGFVCVAEATF 874
Score = 38.5 bits (88), Expect = 0.078
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLC 1157
++C PC HGGSC+DL + C C G C
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 37.4 bits (85), Expect = 0.17
Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 1081 CEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV 1123
CE+ + C PC HGG+C + C+C + G C D++
Sbjct: 603 CERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 37.0 bits (84), Expect = 0.23
Identities = 14/34 (41%), Positives = 16/34 (47%)
Query: 964 DPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQC 997
+ C PC+HGG C FRC C GP C
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
Score = 36.2 bits (82), Expect = 0.38
Identities = 20/66 (30%), Positives = 25/66 (37%), Gaps = 4/66 (6%)
Query: 769 CELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECA---GPAPCGPHGI 825
CE C P PC HGG C C C + +GP C ++ G AP +
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFR-CDCARPHRGPTCADEIPAATFGLGGAPSSASFL 661
Query: 826 CTNLAG 831
L G
Sbjct: 662 LQELPG 667
Score = 36.2 bits (82), Expect = 0.38
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADI 1206
CE E C P P C+H G+CVDL FRC C + G C +I
Sbjct: 603 CERREQ-CRPLP-------CVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 36.2 bits (82), Expect = 0.38
Identities = 23/86 (26%), Positives = 30/86 (34%), Gaps = 5/86 (5%)
Query: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ-- 94
G + PC NGG C + + C CP + G C + C PC C+
Sbjct: 804 GCVSEDMCSPDPCFNGGTCL-VTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEV 862
Query: 95 --SSVVAGTARFSCRCPRGFRGPDCS 118
V A F P F G + S
Sbjct: 863 PDGFVCVAEATFREGPPAAFSGHNAS 888
Score = 35.4 bits (80), Expect = 0.66
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Query: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC 554
D C+ PC NG C+ + + C C F G C + + C PC
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPC 853
Score = 35.0 bits (79), Expect = 0.86
Identities = 20/69 (28%), Positives = 25/69 (36%), Gaps = 5/69 (7%)
Query: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC 408
C +D C +PC C + CTCP FTG C Q + PC C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFH--CTCPANFTGPTCAQ---QLWCPGQPCLPPATC 859
Query: 409 VNTQGSFLC 417
F+C
Sbjct: 860 EEVPDGFVC 868
Score = 34.7 bits (78), Expect = 1.1
Identities = 30/109 (27%), Positives = 43/109 (39%), Gaps = 22/109 (20%)
Query: 185 CPAGY---TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL-----------PGFEG 230
CPA +GP+ P P G + Q GD T+ CL P G
Sbjct: 540 CPARLCVASGPVALASTASATPLPA--GISSAQLGDATF-AGCLQDVRVDGHLLLPEDLG 596
Query: 231 QN----CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
+N CE + C C++GG+CVD + C C G C +++
Sbjct: 597 ENVLLGCERR-EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEI 644
Score = 33.1 bits (74), Expect = 3.3
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 6/38 (15%)
Query: 1255 CQHGGQCRPSPGPGGGLT------FTCHCAQPFWGPRC 1286
C+ QCRP P GG F C CA+P GP C
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTC 640
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1021 (30%), Positives = 395/1021 (38%), Gaps = 227/1021 (22%)
Query: 2 GPG----ARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQ 57
GPG A R RP+ PP + L + P A P P R
Sbjct: 395 GPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP-RPDP 453
Query: 58 LPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
P E P W G SGP +G +CQ R P
Sbjct: 454 RPGPELPLPSIPAWTGPEIP-----ESGPSSG--MCQ------------------RNPQV 488
Query: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
P C+S P + C+C G+ QG C DVDECR P G
Sbjct: 489 CGPGRCISRPSG------------YTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR 535
Query: 174 CLNTPGSFRCQCPAGY-TGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCAC 224
C N+PGSFRC C G+ GP A C P PC G G ++ C C
Sbjct: 536 CENSPGSFRCVCGPGFRAGP----RAAECLDVDECHRVPPPCDLGRCENTPG--SFLCVC 589
Query: 225 LPGFE----GQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ 279
G++ G +C+ +VD+C L G G C + ++ C CP + G C EDVDEC
Sbjct: 590 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 648
Query: 280 LQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCATA--VCFHGATCHDRV 333
+P C G C NT G C C G+ G C Q++D+CA + C +G C +
Sbjct: 649 QEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYG-RCENTE 705
Query: 334 ASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC-TCPPG--FTGG 386
SF C CPMG G C D C ++ C +P G C TCP G G
Sbjct: 706 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSFQCRTCPSGHHLHRG 763
Query: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE----TDVNECLSGP-CR 441
C DVDECS GA PC G C NT+GSF C C GY P DVNECL G C
Sbjct: 764 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCF 822
Query: 442 NQATCLDRIGQFTCICMAGF----TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
CL+ G F C C G+ G C +D+DEC G+C + F C CP
Sbjct: 823 PHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPP 881
Query: 498 GFSG----STCQLDVDECAST-PCRNGA-KCVDQPDGYEC--RCAEGF----EGTLCDRN 545
G ++C LDVDEC P G+ +C + P Y C C G+ EGT CD +
Sbjct: 882 GHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CD-D 938
Query: 546 VDDC---SPDPCHHGRCVDGIASFSC--ACAPGY---TGTRCESQVDECRSQP-CRHGGK 596
VD+C P+ C RC + S+ C AC PGY G C+ VDECR++ C
Sbjct: 939 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 997
Query: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNV 656
C +L + C C G G RDG + C V
Sbjct: 998 CQNLPGSFQCLCDQGYEG-------------------ARDGRH---C------------V 1023
Query: 657 EINECAS--SPCGEGGSCVDGENGFRCLCP--PGSLPPL---CLPPSHPCAHEPCSHGIC 709
++NEC + CG C + E F C+CP P P+ C+PP P S
Sbjct: 1024 DVNECETLQGVCG-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA 1082
Query: 710 YDAP-----------------------GGFRCVCEPGWSGP-RCSQSLARDACESQPCRA 745
+P G R C + P C LAR+ + C
Sbjct: 1083 PASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCT 1142
Query: 746 GGTCSSDGMGFHCTCP--PGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
G +G G C PG + + + L C HG + G L +
Sbjct: 1143 VG----EGWGSGCRIQQCPGTETAEYQSL-------CPHGRGYLAPSGDLSL-------- 1183
Query: 804 GPRCQQDVDECA--GPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCDPNP 857
++DVDEC C G+C N A +SC C GY C + D P
Sbjct: 1184 ----RRDVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP 1238
Query: 858 CLNGGSCQDGVGSFSCSCLPGF----AGPRCARDVDECLSNPCGPGTCTDHV-ASFTCTC 912
GG C + VGS+ C+C P + RC + + L + G C V A C+
Sbjct: 1239 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD--NLGVCWQEVGADLVCSH 1296
Query: 913 P 913
P
Sbjct: 1297 P 1297
Score = 300 bits (769), Expect = 8e-81
Identities = 388/1371 (28%), Positives = 501/1371 (36%), Gaps = 341/1371 (24%)
Query: 249 GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-- 306
G C G N C EDVDEC H G C NT GG++CVC +G+
Sbjct: 275 GPCPTGFERVNGSC----------EDVDECATGGRCQH--GECANTRGGYTCVCPDGFLL 322
Query: 307 --TGESC-SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHED 363
+ SC SQ++ A CF D S + K C C
Sbjct: 323 DSSRSSCISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQ-- 378
Query: 364 AICDTNPVNG-RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR- 421
+C G R IC PG+ A D + +G P R +Q L R
Sbjct: 379 -LCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP----PRVSLSQPRTLPATSRP 433
Query: 422 --------------------------------GYTGPRCETDVNECLSGPCRNQ------ 443
+TGP E + SG C+
Sbjct: 434 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP--EIPESGPSSGMCQRNPQVCGP 491
Query: 444 ATCLDRIGQFTCICMAGF----TGTYCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTCPS 497
C+ R +TC C +GF GT C +D+DEC+ PC G C++ F C C
Sbjct: 492 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGP 549
Query: 498 GF----SGSTCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVD 547
GF + C LDVDEC PC G +C + P + C C G++ G C ++VD
Sbjct: 550 GFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASC-QDVD 606
Query: 548 DC--SPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG-GKCLDLVDKY 604
+C SP C G C + SF C C G+ G+ CE VDEC +P G G+C + +
Sbjct: 607 ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF 666
Query: 605 LCRCPSG----TTGVNCEVNIDDCASN--PCTFGVCRDGINRYDCVC----QPGFTGPLC 654
C CP+G G C+ ++D+CA + PCT+G C + + CVC QP G C
Sbjct: 667 HCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 725
Query: 655 N---------------------------------------VEINECASS--PCGEGGSCV 673
+++EC+S PCG G C
Sbjct: 726 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT 785
Query: 674 DGENGFRCLCPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGW- 724
+ E FRC C PG P P PCA C HG C + G F C C PG+
Sbjct: 786 NTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 843
Query: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG 784
GPR + L D C + G C++ F C CPPG + +L S + C G
Sbjct: 844 PGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP-DLASCLDVDECRERG 902
Query: 785 -------RCESAPGQLP-VCSCPQGWQ-GPR-CQQDVDECA--GPAPCGPHGICTNLAGS 832
RCE++PG V C G+ GP DVDEC GP CG C N GS
Sbjct: 903 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGS 961
Query: 833 FSCT--CHGGY---TGPSCDQDINDC-DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
+ CT C GY G C QD+++C + + C CQ+ GSF C C G+ G R R
Sbjct: 962 YRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1020
Query: 887 ---DVDEC--LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 941
DV+EC L CG C + SF C CP F P + G CV
Sbjct: 1021 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEF---------DPMT----GRCVP 1067
Query: 942 GVNSFSCLCRPGYTGAHCQHEADPCL-SRPCLHGGVCSAAHPGFRCTCLESFTGP-QCQT 999
S + G+ Q A P L +RP P T + G + +
Sbjct: 1068 PRTSAGT-----FPGSQPQAPASPVLPARP------PPPPLPRRPSTPRQGPVGSGRREC 1116
Query: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCP--PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA 1057
D + C N T C C GW G C I+ P E A + LC
Sbjct: 1117 YFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQCPGTETA-----EYQSLCPH 1170
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA---QPCQHGGTCRGYMGGYMCECLPGY 1114
G + P G ++VD C Q C+ G C GY C C GY
Sbjct: 1171 G---------RGYLAPSGDLS--LRRDVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1218
Query: 1115 ----NGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP 1169
C D+ DECA +P GG C++ V Y C+C P +
Sbjct: 1219 YYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---------------- 1261
Query: 1170 LD-SGPRCLHN---------GTCVDLVGG-FRCTCPPGYTGLRCEADINECRSGACHAAH 1218
LD S RC+ N G C VG C+ P L +A EC C
Sbjct: 1262 LDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP----RLDRQATYTEC----C---- 1309
Query: 1219 TRDCLQDPGGGFRC-LCHAGFSG---PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT 1274
CL G C LC A S C + P S P RP G GL +
Sbjct: 1310 ---CLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP-------RPG---GFGLPYE 1356
Query: 1275 CHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGA 1334
+GP +G P Q P GP PP L P PP
Sbjct: 1357 -------YGP--------------DLGPPYQGLPYGPELYPPPALPYD-----PYPPPPG 1390
Query: 1335 SNASCAAAPCLHGGSCRPAPL-APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQ 1393
A R AP AP F + GP E+ A AP R P
Sbjct: 1391 PFAR------------REAPYGAPRFDMPDFEDDGGPYGESEAPAPP-GPGTRWP----Y 1433
Query: 1394 AKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRL--FNNSRC 1442
R +R E P +GG + S+ +P+ + EA +C L N RC
Sbjct: 1434 RSRDTRRSFPEPEEPP---EGGSYAGSLAEPYEELEAEECGILDGCTNGRC 1481
Score = 268 bits (685), Expect = 5e-71
Identities = 292/1031 (28%), Positives = 390/1031 (37%), Gaps = 181/1031 (17%)
Query: 43 CLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHS--------GPC--- 87
C D CA GGRC C+CP G++ + + C S GPC
Sbjct: 288 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSR--SSCISQHVISEAKGPCFRV 345
Query: 88 AGRGVCQSSVVAGTARFSCRCPRGFR--GPDCSLPDPCLSSPCAHGAR--CSVGPDGRFL 143
G C ++ + C C R + G C L P S G R C GP +
Sbjct: 346 LRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSE----GFREICPAGPGYHYS 401
Query: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE-------N 196
S Y R + + +P T + G P P E
Sbjct: 402 AS-DLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFL----PTHRLEPRPEPRPDPRPG 456
Query: 197 PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN 256
P +P P G +SG C+ N C G C+ +
Sbjct: 457 PELPLPSIPAWTGPEIPESGP-----------SSGMCQRNPQVC------GPGRCISRPS 499
Query: 257 TYNCQCPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-TGESC 311
Y C C + G C DVDEC+ P C G C N+ G CVC G+ G
Sbjct: 500 GYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 557
Query: 312 SQ--NIDDC--ATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNP--CH 361
++ ++D+C C G C + SF C CP G G C D C +P C
Sbjct: 558 AECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 616
Query: 362 EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR 421
A C P + R C CP GF G AC++DVDEC+ PC GRC NT GSF C C
Sbjct: 617 RGA-CKNLPGSFR--CVCPAGFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPA 672
Query: 422 GYT----GPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAGF----TGTYCEVDIDE 472
G+ G C+ DV+EC S P C + G F C+C GF G+ CE D+DE
Sbjct: 673 GFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDE 730
Query: 473 CQSSPCVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECAS--TPCRNGAKCVDQPD 527
C++ G C + F C TCPSG C DVDEC+S PC C +
Sbjct: 731 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEG 789
Query: 528 GYECRCAEGFE------GTLCDRNV----DDCSPDPCHHGRCVDGIASFSCACAPGYT-- 575
+ C CA G+ G D N D C P HG C++ SF+C CAPGY
Sbjct: 790 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP----HGECLNTDGSFACTCAPGYRPG 845
Query: 576 --GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTG----VNCEVNIDDCASNP- 628
G C VDEC + G C + + C CP G +C +++D+C
Sbjct: 846 PRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGP 903
Query: 629 --CTFGVCRDGINRYDCV--CQPGF-TGP--LCNVEINECAS---SPCGEGGSCVDGENG 678
C C + Y CV C PG+ GP C+ +++EC CG C +
Sbjct: 904 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICG-AQRCENTPGS 961
Query: 679 FRCL--CPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGWSGPR 728
+RC C PG P P C + C +H +C + PG F+C+C+ G+ G R
Sbjct: 962 YRCTPACDPGYQPT----PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1017
Query: 729 CSQSLAR-DACES-QPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG--- 783
+ + CE+ Q C + F C CP + + C P G
Sbjct: 1018 DGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD-PMTGRCVPPRTSAGTFP 1076
Query: 784 GRCESAPGQ--LPVCSCP-----------QGWQGPRCQQDVDECAGPAPCGPHGICTNLA 830
G AP LP P QG G ++ + A P C + + N+
Sbjct: 1077 GSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACD-NILARNVT 1135
Query: 831 GSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGS-CQDGVGSFSCSCLPGFAGPRCARDVD 889
C G G C I C S C G G + S RDVD
Sbjct: 1136 WQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGRGYLAPS-----GDLSLRRDVD 1188
Query: 890 ECL---SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ----DLPDCSPSS-CFNGGTCVD 941
EC C G C + ++C C GY +H ++ D +C+ GG CV+
Sbjct: 1189 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGRCVN 1247
Query: 942 GVNSFSCLCRP 952
V S+ C C P
Sbjct: 1248 TVGSYHCTCEP 1258
Score = 263 bits (673), Expect = 1e-69
Identities = 268/901 (29%), Positives = 367/901 (40%), Gaps = 194/901 (21%)
Query: 474 QSSPCVNG-------GVCKDRVNGFSCTCPSG--------FSGSTCQLDVDECASTPCRN 518
QS+P +G G C + G C P G+ V +C R
Sbjct: 205 QSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERL 264
Query: 519 G-AKCVDQPDGYECRCAEGFEGT--LCDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGY 574
G ++ V PDG C GFE C+ +VD+C+ C HG C + ++C C G+
Sbjct: 265 GNSERVSAPDG---PCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPDGF 320
Query: 575 ----TGTRCESQ--VDECRSQPC----RHGGKCLDL---VDKYLCRCP--SGTTGVNCEV 619
+ + C SQ + E + PC R GG L + + K +C C G C++
Sbjct: 321 LLDSSRSSCISQHVISEAKG-PCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQL 379
Query: 620 NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGF 679
C FG +G R C PG+ ++ N + P G+ V
Sbjct: 380 ----CP----PFG--SEGF-REICPAGPGYHYSASDLRYN---TRPLGQEPPRVS----- 420
Query: 680 RCLCPPGSLPPLCLP----------------------------PSHP------------- 698
L P +LP P PS P
Sbjct: 421 --LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPS 478
Query: 699 ---CAHEP--CSHGICYDAPGGFRCVCEPGWS-GPRCSQSLARDACE--SQPCRAGGTCS 750
C P C G C P G+ C C+ G+ P+ ++ + D C PC A G C
Sbjct: 479 SGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPC-APGRCE 537
Query: 751 SDGMGFHCTCPPGV----QGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCSCPQGWQ- 803
+ F C C PG + +C + C P PC+ GRCE+ PG +C CP G+Q
Sbjct: 538 NSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDL-GRCENTPGSF-LCVCPAGYQA 595
Query: 804 ---GPRCQQDVDECA-GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDC--DPNP 857
G C QDVDEC P CG G C NL GSF C C G+ G +C++D+++C +P P
Sbjct: 596 APHGASC-QDVDECTQSPGLCG-RGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP 653
Query: 858 CLNGGSCQDGVGSFSCSCLPGF--AGPRC-ARDVDECLSN--PCGPGTCTDHVASFTCTC 912
C G C + GSF C+C GF GP +DVDEC + PC G C + SF C C
Sbjct: 654 C-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVC 712
Query: 913 PPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQH----EAD 964
P G+ G CE D+ +C G CV+ SF C P +G H + D
Sbjct: 713 PMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCP--SGHHLHRGRCTDVD 769
Query: 965 PCLS--RPCLHGGVCSAAHPGFRCTCLESFTGPQ-----CQTLVDWCSRQPCQNGGRCVQ 1017
C S PC G C+ FRC+C + P C + + C G C+
Sbjct: 770 ECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLN 829
Query: 1018 T-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG 1075
T G++ C C PG+ L E + E LCQ+ G C + D S C+CP G
Sbjct: 830 TDGSFACTCAPGYRPGPRGASCLDVDECSE------EDLCQS-GICTNTDGSFECICPPG 882
Query: 1076 -RTGSHCEQ--EVDPCLAQ-PCQHGG-TCRGYMGGYMC--ECLPGYNG--DNCEDDVDEC 1126
R G +VD C + P G C G Y C +C PGY+ + DDVDEC
Sbjct: 883 HRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDEC 942
Query: 1127 ASQPCQHGGS--CIDLVARYLC--SCPPG---TLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
+ G+ C + Y C +C PG T G C+ + D+C + C +
Sbjct: 943 QEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDEC------RNRSFCGAH 995
Query: 1180 GTCVDLVGGFRCTCPPGYTGLR----CEADINECRS--GACHAAHTRDCLQDPGGGFRCL 1233
C +L G F+C C GY G R C D+NEC + G C AA ++ G F C+
Sbjct: 996 AVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAA----LCENVEGSFLCV 1050
Query: 1234 C 1234
C
Sbjct: 1051 C 1051
Score = 263 bits (671), Expect = 2e-69
Identities = 325/1112 (29%), Positives = 436/1112 (39%), Gaps = 223/1112 (20%)
Query: 486 DRVNGFSCTCPSGFS--GSTCQLDVDECASTP-CRNGAKCVDQPDGYECRCAEGFEGTLC 542
+RV+ CP+GF +C+ DVDECA+ C++G +C + GY C C +GF L
Sbjct: 268 ERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF---LL 322
Query: 543 DRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC----RHGGKCL 598
D + C I+ + A G PC R GG L
Sbjct: 323 DSSRSSC-------------ISQHVISEAKG----------------PCFRVLRDGGCSL 353
Query: 599 DL---VDKYLCRCP--SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPL 653
+ + K +C C G C++ C FG +G R C PG+
Sbjct: 354 PILRNITKQICCCSRVGKAWGRGCQL----CP----PFG--SEGF-REICPAGPGYHYSA 402
Query: 654 CNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP-----PSHPCAHEPCSHGI 708
++ N + P G+ V L P +LP P P+H P
Sbjct: 403 SDLRYN---TRPLGQEPPRVS-------LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 452
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQS-LARDACESQPCRAG-GTCSSDGMGFHCTCPPGV-- 764
P P W+GP +S + C+ P G G C S G+ C C G
Sbjct: 453 PRPGP-ELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRL 511
Query: 765 --QGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQQ--DVDECAGP 817
QG +C + C P PC GRCE++PG C C G++ GPR + DVDEC
Sbjct: 512 SPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFR-CVCGPGFRAGPRAAECLDVDECHRV 569
Query: 818 APCGPHGICTNLAGSFSCTCHGGYT----GPSCDQDINDCDPNPCLNG-GSCQDGVGSFS 872
P G C N GSF C C GY G SC QD+++C +P L G G+C++ GSF
Sbjct: 570 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSPGLCGRGACKNLPGSFR 628
Query: 873 CSCLPGFAGPRCARDVDECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLP 926
C C GF G C DVDEC PCGPG C + SF C CP G+ G C QD+
Sbjct: 629 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVD 687
Query: 927 DC--SPSSCFNGGTCVDGVNSFSCLC----RPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
+C SP C G C + SF C+C +P G+ C+ + D C + G C +
Sbjct: 688 ECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 745
Query: 981 HPGFRCTCLES---FTGPQCQTLVDWCS--RQPCQNGGRCVQT-GAY-CLCPPGWSGRLC 1033
F+C S +C T VD CS PC G C T G++ C C PG+ R
Sbjct: 746 PGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY--RAP 802
Query: 1034 DIRSLPCREAAAQIGVRLE-QLCQAGGQCVDEDSSHYCVCP----EGRTGSHCEQEVDPC 1088
R PC A + LE C G+C++ D S C C G G+ C +VD C
Sbjct: 803 SGRPGPC----ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDEC 857
Query: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGD----NCEDDVDECASQPCQHGGS--CIDLVA 1142
+ G C G + C C PG+ +C DVDEC + GS C +
Sbjct: 858 SEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPG 916
Query: 1143 RYLC--SCPPGTLG---VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT--CPP 1195
Y C C PG C+ + D+C + GP C + G +RCT C P
Sbjct: 917 SYRCVRDCDPGYHAGPEGTCD-DVDEC-----QEYGPEICGAQRCENTPGSYRCTPACDP 970
Query: 1196 GY---TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
GY G C+ D++ECR+ + AH Q+ G F+CLC G+ G R +
Sbjct: 971 GYQPTPGGGCQ-DVDECRNRSFCGAHA--VCQNLPGSFQCLCDQGYEGAR--------DG 1019
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
+ C +C G G CE V S CP P + P R
Sbjct: 1020 RHCVDVNECETLQGVCGAAL-------------CENVEGSFL-CVCP-NSPEEFDPMTGR 1064
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGP-- 1370
C P +G +FPGS P A A+P L P P P QG G
Sbjct: 1065 CVPPRTSAG----TFPGSQPQA-----PASPVLPARP--PPPPLPRRPSTPRQGPVGSGR 1113
Query: 1371 -RCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC- 1428
C AAP+ + Q C C + G GW G C + +QC
Sbjct: 1114 RECYFDTAAPDACDNILARNVTW------QEC---CCTVGEGW-GSGCRI------QQCP 1157
Query: 1429 --EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCN--------PVYEKYCAD- 1477
E + L + R A S L + D R++ C P Y YC++
Sbjct: 1158 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1217
Query: 1478 ---HFADGRC--DQGCNTEECGWDGLDCASEV 1504
H C + C EE +G C + V
Sbjct: 1218 YYYHTQRLECIDNDECADEEPACEGGRCVNTV 1249
Score = 250 bits (639), Expect = 1e-65
Identities = 310/1099 (28%), Positives = 401/1099 (36%), Gaps = 249/1099 (22%)
Query: 48 PCANGGRCTQLPSREAACLCPPGW-VGER---CQLEDPCHS-GPCAGRGVCQSSVVAGTA 102
PCA G RC P C+C PG+ G R C D CH P G C+++
Sbjct: 530 PCAPG-RCENSPG-SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENT----PG 583
Query: 103 RFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
F C CP G++ G C D C SP C GA C P G F C CP G++G +C
Sbjct: 584 SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE 641
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPC--------APSPCRN 208
DVDEC P G C NT GSF C CPAG+ P PC +P PC
Sbjct: 642 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS---RGPGAPCQDVDECARSPPPCTY 698
Query: 209 GGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPP 264
G G ++ C C GF+ G CE +VD+C H G CV+ ++ C+ P
Sbjct: 699 GRCENTEG--SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCP 755
Query: 265 E----WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES-----CSQNI 315
G+ CT DVDEC C G C NT G C C G+ S C+ ++
Sbjct: 756 SGHHLHRGR-CT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DV 812
Query: 316 DDCATA-VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNPCHEDAICDTNP 370
++C CF C + SF C C G G C D C + IC TN
Sbjct: 813 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TN- 870
Query: 371 VNGRAICTCPPGFTGG---ACDQDVDECSIGANPCEHLGRCVNTQGSFLC--QCGRGY-T 424
+G C CPPG G A DVDEC RC N+ GS+ C C GY
Sbjct: 871 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 930
Query: 425 GPR--CETDVNECLS-GP--CRNQATCLDRIGQFTC--ICMAGF---TGTYCEVDIDECQ 474
GP C+ DV+EC GP C Q C + G + C C G+ G C+ D+DEC+
Sbjct: 931 GPEGTCD-DVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECR 987
Query: 475 S-SPCVNGGVCKDRVNGFSCTCPSGFSGST----CQLDVDECASTPCRNGAKCVDQPDG- 528
+ S C VC++ F C C G+ G+ C +DV+EC + GA + +G
Sbjct: 988 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGS 1046
Query: 529 YECRC--------------------AEGFEGTLCDRNVDDCSP----------------- 551
+ C C A F G+ P
Sbjct: 1047 FLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1106
Query: 552 DPCHHGR---CVDGIASFSC--ACAPGYTGTRCESQVDE-----CRSQPCRHGGKCLDLV 601
P GR D A +C A T C V E CR Q C
Sbjct: 1107 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETA---- 1162
Query: 602 DKYLCRCPSG------TTGVNCEVNIDDC---ASNPCTFGVCRDGINRYDCVCQPGF--- 649
+Y CP G + ++ ++D+C C GVC + Y C C G+
Sbjct: 1163 -EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYH 1221
Query: 650 TGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS-HPCAHEPCSH- 706
T L ++ +ECA P EGG CV+ + C C PPL L S C
Sbjct: 1222 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE----PPLVLDGSQRRCVSNESQSL 1277
Query: 707 ----GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPP 762
G+C+ G VC S PR L R A ++ C G + G C P
Sbjct: 1278 DDNLGVCWQEVGA-DLVC----SHPR----LDRQATYTECCCLYG----EAWGMDCALCP 1324
Query: 763 GVQGRQ----CELLSPCTPNPCEHGG---------------------------------R 785
C +L P +P GG
Sbjct: 1325 AQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDP 1384
Query: 786 CESAPGQLPVCSCPQG---WQGPRCQQD---VDECAGPAPCGPHGICTNLAGSFSCTCHG 839
PG P G + P + D E PAP GP
Sbjct: 1385 YPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGP----------------- 1427
Query: 840 GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-LSNPCGP 898
G P +D P P +G GS++ S A P + +EC + + C
Sbjct: 1428 GTRWPYRSRDTRRSFPEP----EEPPEG-GSYAGS----LAEPYEELEAEECGILDGCTN 1478
Query: 899 GTCTDHVASFTCTCPPGY----GGFHC----EQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
G C FTC C GY C E D + + C N C++ SF C+C
Sbjct: 1479 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN-ARCLNTDGSFRCIC 1537
Query: 951 RPGYTGAHCQHEADPCLSR 969
RPG+ H H P R
Sbjct: 1538 RPGFAPTHQPHHCAPARPR 1556
Score = 240 bits (612), Expect = 1e-62
Identities = 279/990 (28%), Positives = 370/990 (37%), Gaps = 203/990 (20%)
Query: 570 CAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
C G C S + R+Q CR G + D LC S G + V+ D
Sbjct: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLC---SERLGNSERVSAPD---- 274
Query: 628 PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
G C G R + C+ +++ECA+ + G C + G+ C+CP G
Sbjct: 275 ----GPCPTGFERVNGSCE----------DVDECATGGRCQHGECANTRGGYTCVCPDGF 320
Query: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGG-FRCVCEPGWSGPRCSQSLARDACESQPCRAG 746
L L S S + +A G FR + + G S P + C S+ +A
Sbjct: 321 L----LDSSRSSC---ISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW 373
Query: 747 G----TCSSDGM-GFHCTCP--PGVQGRQCEL--------------------LSPCTPNP 779
G C G GF CP PG +L P T P
Sbjct: 374 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRP 433
Query: 780 C-----------EHGGRCESAPG-QLPVCSCPQGWQGPRCQQDVDECA----GPAPCGPH 823
R + PG +LP+ S P W GP + P CGP
Sbjct: 434 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIP-AWTGPEIPESGPSSGMCQRNPQVCGP- 491
Query: 824 GICTNLAGSFSCTCHGGY----TGPSCDQDINDCD--PNPCLNGGSCQDGVGSFSCSCLP 877
G C + ++C C G+ G C D+++C P PC G C++ GSF C C P
Sbjct: 492 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGP 549
Query: 878 GF-AGPRCAR--DVDEC--LSNPCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDC 928
GF AGPR A DVDEC + PC G C + SF C CP GY G C QD+ +C
Sbjct: 550 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC 608
Query: 929 --SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGFR 985
SP C G C + SF C+C G+ G+ C+ + D C P G G C F
Sbjct: 609 TQSPGLC-GRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFH 667
Query: 986 CTCLESF----TGPQCQTLVDWCSRQ--PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRS 1037
C C F G CQ VD C+R PC GRC T G++ C+CP G+
Sbjct: 668 CACPAGFRSRGPGAPCQD-VDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC 725
Query: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC-VCPEGR--TGSHCEQEVDPCL--AQP 1092
E L G +CV+ S C CP G C +VD C A P
Sbjct: 726 EDVDECE-------NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPP 777
Query: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCED----DVDECASQP-CQHGGSCIDLVARYLCS 1147
C G C G + C C PGY + DV+EC C G C++ + C+
Sbjct: 778 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACT 837
Query: 1148 CP----PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG---L 1200
C PG G C ++ D+C S +G C + G F C CPPG+ L
Sbjct: 838 CAPGYRPGPRGASC-LDVDEC-------SEEDLCQSGICTNTDGSFECICPPGHRAGPDL 889
Query: 1201 RCEADINECRSGACHAAHTRDCLQDPGGGFRCL--CHAGF-SGPR--CQTV-----LSP- 1249
D++ECR ++ C P G +RC+ C G+ +GP C V P
Sbjct: 890 ASCLDVDECRERGPALCGSQRCENSP-GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 948
Query: 1250 -CESQPCQH---GGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQ 1305
C +Q C++ +C P+ PG QP G C+ V C CQ
Sbjct: 949 ICGAQRCENTPGSYRCTPACDPG---------YQPTPGGGCQDVDECRNRSFCGAHAVCQ 999
Query: 1306 QTPRGPRCACPPGLSGP----------SCRSFPGSPPGASNASCAAAPC--LHGGSCRPA 1353
P +C C G G C + G C AA C + G
Sbjct: 1000 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG--------VCGAALCENVEGSFLCVC 1051
Query: 1354 PLAP------FFRC----ACAQGWTGPRCEAPA-----AAPEVSEEPRCPRAACQAKRGD 1398
P +P RC A + G + +APA A P PR P Q G
Sbjct: 1052 PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1111
Query: 1399 QRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
R REC D D L+ W++C
Sbjct: 1112 GR--RECYFDTAAPDACDNILARNVTWQEC 1139
Score = 166 bits (419), Expect = 3e-40
Identities = 262/990 (26%), Positives = 341/990 (34%), Gaps = 215/990 (21%)
Query: 607 RCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
RC G TG C CA T G PGF LC + C
Sbjct: 44 RCVHGPTGSRCTPT---CAPRNATS--VDSGAPGGAAPGGPGFRAFLCPLI--------C 90
Query: 667 GEGGSCVDGENGFRCLCPP------------GSLPPLCLPP-------SHPCA-HEPCSH 706
GG CV + RCLCPP G+ PP P + P A H H
Sbjct: 91 HNGGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEH 147
Query: 707 GIC------YDAPGGFRCVCEP--GWSGP----------RCSQSLARDAC-------ESQ 741
G+ + P V SGP R + +A +S
Sbjct: 148 GVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSA 207
Query: 742 PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCS-- 797
P R G + G G+ C ++G +C P T C G +CS
Sbjct: 208 P-REDGYSDASGFGY---CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSER 263
Query: 798 -------------CPQGWQGPRCQ-QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGY-- 841
CP G++ +DVDECA C HG C N G ++C C G+
Sbjct: 264 LGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC-QHGECANTRGGYTCVCPDGFLL 322
Query: 842 --TGPSC-DQDINDCDPNPCL----NGGS-------------CQDGVGSF---SCSCLPG 878
+ SC Q + PC +GG C VG C P
Sbjct: 323 DSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPP 382
Query: 879 F----------AGPRCARDVDECLSN--PCG---PGTCTDHVASFTCTCPPGYGGFHCEQ 923
F AGP + N P G P + T P G +
Sbjct: 383 FGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHR 442
Query: 924 DLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP----CLSRPCLHG-GVCS 978
P P G P +TG E+ P C P + G G C
Sbjct: 443 LEPRPEPRPDPRPGP------ELPLPSIPAWTGPEIP-ESGPSSGMCQRNPQVCGPGRCI 495
Query: 979 AAHPGFRCTCLESFT----GPQCQTLVDWCSR--QPCQNGGRCVQT-GAY-CLCPPGWSG 1030
+ G+ C C F G +C VD C R PC G RC + G++ C+C PG+
Sbjct: 496 SRPSGYTCACDSGFRLSPQGTRCID-VDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRA 553
Query: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRT----GSHCEQEVD 1086
L E R+ C G +C + S CVCP G G+ C Q+VD
Sbjct: 554 GPRAAECLDVDECH-----RVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASC-QDVD 606
Query: 1087 PCLAQPCQHG-GTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHG-GSCIDLVARY 1144
C P G G C+ G + C C G+ G CE+DVDECA +P G G C + +
Sbjct: 607 ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF 666
Query: 1145 LCSCPPGTL----GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY--- 1197
C+CP G G C+ + D+C P P C + G C + G F+C CP G+
Sbjct: 667 HCACPAGFRSRGPGAPCQ-DVDECARSP-----PPCTY-GRCENTEGSFQCVCPMGFQPN 719
Query: 1198 -TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRC-LCHAG--FSGPRCQTVLSPCES- 1252
G CE D++EC + A ++C+ PG F+C C +G RC T + C S
Sbjct: 720 TAGSECE-DVDECENHL--ACPGQECVNSPGS-FQCRTCPSGHHLHRGRC-TDVDECSSG 774
Query: 1253 -QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPR-----CERVARSCRELQCPVGVPCQQ 1306
PC G C + G +F C CA + P C V C C
Sbjct: 775 APPCGPHGHCTNTEG-----SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLN 829
Query: 1307 TPRGPRCACPPGLSGPSCRSFPGSPPGASNAS---CAAAPCLHGGSCRPAPLAPFFRCAC 1363
T C C PG PG P GAS C+ G C + F C C
Sbjct: 830 TDGSFACTCAPGYR-------PG-PRGASCLDVDECSEEDLCQSGICTNTDGS--FECIC 879
Query: 1364 AQGW-TGPRCEAPAAAPEVSEE--PRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLS 1420
G GP + E E C C+ G RC R+C+ G C
Sbjct: 880 PPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-D 938
Query: 1421 VGDPWRQ----CEALQCWRLFNNSRCDPAC 1446
V + C A +C + RC PAC
Sbjct: 939 VDECQEYGPEICGAQRCENTPGSYRCTPAC 968
Score = 56.2 bits (134), Expect = 4e-07
Identities = 37/101 (36%), Positives = 46/101 (45%), Gaps = 21/101 (20%)
Query: 108 CPRGFRGPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCS---------------CPPGY 150
C R RG +C+ P P L + C GA + G LCS CP G+
Sbjct: 222 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 281
Query: 151 Q--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY 189
+ SC DVDEC G C+HG C NT G + C CP G+
Sbjct: 282 ERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 320
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1179 NGTCVDLVGGFRCTCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRC 1232
NG CV + GF C C GY T + C DINEC A CL + G FRC
Sbjct: 1478 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCL-NTDGSFRC 1535
Query: 1233 LCHAGFS 1239
+C GF+
Sbjct: 1536 ICRPGFA 1542
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 13/95 (13%)
Query: 618 EVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINEC----ASSPCGE 668
E+ ++C + CT G C + C C G+ T C V+INEC A+SP
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1522
Query: 669 GGSCVDGENGFRCLCPPGSLP---PLCLPPSHPCA 700
C++ + FRC+C PG P P P+ P A
Sbjct: 1523 NARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1557
Score = 37.0 bits (84), Expect = 0.23
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 13/71 (18%)
Query: 446 CLDRIGQFTCI------CMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
C +R+G + C GF CE D+DEC + G C + G++C CP
Sbjct: 260 CSERLGNSERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHGECANTRGGYTCVCPD 318
Query: 498 GF----SGSTC 504
GF S S+C
Sbjct: 319 GFLLDSSRSSC 329
Score = 36.6 bits (83), Expect = 0.29
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 10/83 (12%)
Query: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGP 1174
E + +EC G C+ + + C C G T +INE D + P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEA----ASP 1519
Query: 1175 RCLHNGTCVDLVGGFRCTCPPGY 1197
C+ N C++ G FRC C PG+
Sbjct: 1520 LCV-NARCLNTDGSFRCICRPGF 1541
Score = 35.8 bits (81), Expect = 0.50
Identities = 30/95 (31%), Positives = 35/95 (36%), Gaps = 18/95 (18%)
Query: 177 TPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVN 236
TP +C G TG C CAP T SG PGF C +
Sbjct: 37 TPVVCGLRCVHGPTGSRC---TPTCAP----RNATSVDSGAPGGAAPGGPGFRAFLCPLI 89
Query: 237 VDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
C NGG CV C CPP++ G+FC
Sbjct: 90 --------CHNGGVCV---KPDRCLCPPDFAGKFC 113
Score = 35.8 bits (81), Expect = 0.50
Identities = 23/53 (43%), Positives = 26/53 (49%), Gaps = 18/53 (33%)
Query: 36 PGAAAPPCLDGSP----------CANGGRCTQLPSREAACLCPPGWVGERCQL 78
PG AAP G P C NGG C + P R CLCPP + G+ CQL
Sbjct: 71 PGGAAP----GGPGFRAFLCPLICHNGGVCVK-PDR---CLCPPDFAGKFCQL 115
Score = 35.4 bits (80), Expect = 0.66
Identities = 31/108 (28%), Positives = 39/108 (36%), Gaps = 21/108 (19%)
Query: 715 GFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSP 774
G RCV P +G RC+ + A S A G + G PG + C L+
Sbjct: 42 GLRCVHGP--TGSRCTPTCAPRNATSVDSGAPGGAAPGG--------PGFRAFLCPLI-- 89
Query: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGP 822
C +GG C C CP + G CQ PAP P
Sbjct: 90 -----CHNGGVCVKPDR----CLCPPDFAGKFCQLHSSGARPPAPAVP 128
Score = 33.1 bits (74), Expect = 3.3
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 1082 EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE---DDVDEC----ASQPCQHG 1134
E E + C G C G+ C C GY D D++EC A+ P
Sbjct: 1464 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1523
Query: 1135 GSCIDLVARYLCSCPPG 1151
C++ + C C PG
Sbjct: 1524 ARCLNTDGSFRCICRPG 1540
Score = 32.3 bits (72), Expect = 5.6
Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 28/104 (26%)
Query: 126 SPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP---------------CRH 170
+P G RC GP G C P R+ S VD G C +
Sbjct: 37 TPVVCGLRCVHGPTGS---RCTPTCAPRNATS-VDSGAPGGAAPGGPGFRAFLCPLICHN 92
Query: 171 GGTCLNTPGSFRCQCPAGYTGPLCE------NPAVPCAPSPCRN 208
GG C+ RC CP + G C+ P P P R+
Sbjct: 93 GGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRS 133
Score = 32.3 bits (72), Expect = 5.6
Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 3/29 (10%)
Query: 478 CVNGGVCKDRVNGFSCTCPSGFSGSTCQL 506
C NGGVC V C CP F+G CQL
Sbjct: 90 CHNGGVC---VKPDRCLCPPDFAGKFCQL 115
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1021 (30%), Positives = 395/1021 (38%), Gaps = 227/1021 (22%)
Query: 2 GPG----ARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQ 57
GPG A R RP+ PP + L + P A P P R
Sbjct: 425 GPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP-RPDP 483
Query: 58 LPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
P E P W G SGP +G +CQ R P
Sbjct: 484 RPGPELPLPSIPAWTGPEIP-----ESGPSSG--MCQ------------------RNPQV 518
Query: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
P C+S P + C+C G+ QG C DVDECR P G
Sbjct: 519 CGPGRCISRPSG------------YTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR 565
Query: 174 CLNTPGSFRCQCPAGY-TGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCAC 224
C N+PGSFRC C G+ GP A C P PC G G ++ C C
Sbjct: 566 CENSPGSFRCVCGPGFRAGP----RAAECLDVDECHRVPPPCDLGRCENTPG--SFLCVC 619
Query: 225 LPGFE----GQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ 279
G++ G +C+ +VD+C L G G C + ++ C CP + G C EDVDEC
Sbjct: 620 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 678
Query: 280 LQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCATA--VCFHGATCHDRV 333
+P C G C NT G C C G+ G C Q++D+CA + C +G C +
Sbjct: 679 QEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYG-RCENTE 735
Query: 334 ASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC-TCPPG--FTGG 386
SF C CPMG G C D C ++ C +P G C TCP G G
Sbjct: 736 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSFQCRTCPSGHHLHRG 793
Query: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE----TDVNECLSGP-CR 441
C DVDECS GA PC G C NT+GSF C C GY P DVNECL G C
Sbjct: 794 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCF 852
Query: 442 NQATCLDRIGQFTCICMAGF----TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
CL+ G F C C G+ G C +D+DEC G+C + F C CP
Sbjct: 853 PHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPP 911
Query: 498 GFSG----STCQLDVDECAST-PCRNGA-KCVDQPDGYEC--RCAEGF----EGTLCDRN 545
G ++C LDVDEC P G+ +C + P Y C C G+ EGT CD +
Sbjct: 912 GHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CD-D 968
Query: 546 VDDC---SPDPCHHGRCVDGIASFSC--ACAPGY---TGTRCESQVDECRSQP-CRHGGK 596
VD+C P+ C RC + S+ C AC PGY G C+ VDECR++ C
Sbjct: 969 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 1027
Query: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNV 656
C +L + C C G G RDG + C V
Sbjct: 1028 CQNLPGSFQCLCDQGYEG-------------------ARDGRH---C------------V 1053
Query: 657 EINECAS--SPCGEGGSCVDGENGFRCLCP--PGSLPPL---CLPPSHPCAHEPCSHGIC 709
++NEC + CG C + E F C+CP P P+ C+PP P S
Sbjct: 1054 DVNECETLQGVCG-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA 1112
Query: 710 YDAP-----------------------GGFRCVCEPGWSGP-RCSQSLARDACESQPCRA 745
+P G R C + P C LAR+ + C
Sbjct: 1113 PASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCT 1172
Query: 746 GGTCSSDGMGFHCTCP--PGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
G +G G C PG + + + L C HG + G L +
Sbjct: 1173 VG----EGWGSGCRIQQCPGTETAEYQSL-------CPHGRGYLAPSGDLSL-------- 1213
Query: 804 GPRCQQDVDECA--GPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCDPNP 857
++DVDEC C G+C N A +SC C GY C + D P
Sbjct: 1214 ----RRDVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP 1268
Query: 858 CLNGGSCQDGVGSFSCSCLPGF----AGPRCARDVDECLSNPCGPGTCTDHV-ASFTCTC 912
GG C + VGS+ C+C P + RC + + L + G C V A C+
Sbjct: 1269 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD--NLGVCWQEVGADLVCSH 1326
Query: 913 P 913
P
Sbjct: 1327 P 1327
Score = 300 bits (769), Expect = 8e-81
Identities = 388/1371 (28%), Positives = 501/1371 (36%), Gaps = 341/1371 (24%)
Query: 249 GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-- 306
G C G N C EDVDEC H G C NT GG++CVC +G+
Sbjct: 305 GPCPTGFERVNGSC----------EDVDECATGGRCQH--GECANTRGGYTCVCPDGFLL 352
Query: 307 --TGESC-SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHED 363
+ SC SQ++ A CF D S + K C C
Sbjct: 353 DSSRSSCISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQ-- 408
Query: 364 AICDTNPVNG-RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR- 421
+C G R IC PG+ A D + +G P R +Q L R
Sbjct: 409 -LCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP----PRVSLSQPRTLPATSRP 463
Query: 422 --------------------------------GYTGPRCETDVNECLSGPCRNQ------ 443
+TGP E + SG C+
Sbjct: 464 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP--EIPESGPSSGMCQRNPQVCGP 521
Query: 444 ATCLDRIGQFTCICMAGF----TGTYCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTCPS 497
C+ R +TC C +GF GT C +D+DEC+ PC G C++ F C C
Sbjct: 522 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGP 579
Query: 498 GF----SGSTCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVD 547
GF + C LDVDEC PC G +C + P + C C G++ G C ++VD
Sbjct: 580 GFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASC-QDVD 636
Query: 548 DC--SPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG-GKCLDLVDKY 604
+C SP C G C + SF C C G+ G+ CE VDEC +P G G+C + +
Sbjct: 637 ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF 696
Query: 605 LCRCPSG----TTGVNCEVNIDDCASN--PCTFGVCRDGINRYDCVC----QPGFTGPLC 654
C CP+G G C+ ++D+CA + PCT+G C + + CVC QP G C
Sbjct: 697 HCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 755
Query: 655 N---------------------------------------VEINECASS--PCGEGGSCV 673
+++EC+S PCG G C
Sbjct: 756 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT 815
Query: 674 DGENGFRCLCPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGW- 724
+ E FRC C PG P P PCA C HG C + G F C C PG+
Sbjct: 816 NTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 873
Query: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG 784
GPR + L D C + G C++ F C CPPG + +L S + C G
Sbjct: 874 PGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP-DLASCLDVDECRERG 932
Query: 785 -------RCESAPGQLP-VCSCPQGWQ-GPR-CQQDVDECA--GPAPCGPHGICTNLAGS 832
RCE++PG V C G+ GP DVDEC GP CG C N GS
Sbjct: 933 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGS 991
Query: 833 FSCT--CHGGY---TGPSCDQDINDC-DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
+ CT C GY G C QD+++C + + C CQ+ GSF C C G+ G R R
Sbjct: 992 YRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1050
Query: 887 ---DVDEC--LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 941
DV+EC L CG C + SF C CP F P + G CV
Sbjct: 1051 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEF---------DPMT----GRCVP 1097
Query: 942 GVNSFSCLCRPGYTGAHCQHEADPCL-SRPCLHGGVCSAAHPGFRCTCLESFTGP-QCQT 999
S + G+ Q A P L +RP P T + G + +
Sbjct: 1098 PRTSAGT-----FPGSQPQAPASPVLPARP------PPPPLPRRPSTPRQGPVGSGRREC 1146
Query: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCP--PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA 1057
D + C N T C C GW G C I+ P E A + LC
Sbjct: 1147 YFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQCPGTETA-----EYQSLCPH 1200
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA---QPCQHGGTCRGYMGGYMCECLPGY 1114
G + P G ++VD C Q C+ G C GY C C GY
Sbjct: 1201 G---------RGYLAPSGDLS--LRRDVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1248
Query: 1115 ----NGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP 1169
C D+ DECA +P GG C++ V Y C+C P +
Sbjct: 1249 YYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---------------- 1291
Query: 1170 LD-SGPRCLHN---------GTCVDLVGG-FRCTCPPGYTGLRCEADINECRSGACHAAH 1218
LD S RC+ N G C VG C+ P L +A EC C
Sbjct: 1292 LDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP----RLDRQATYTEC----C---- 1339
Query: 1219 TRDCLQDPGGGFRC-LCHAGFSG---PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT 1274
CL G C LC A S C + P S P RP G GL +
Sbjct: 1340 ---CLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP-------RPG---GFGLPYE 1386
Query: 1275 CHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGA 1334
+GP +G P Q P GP PP L P PP
Sbjct: 1387 -------YGP--------------DLGPPYQGLPYGPELYPPPALPYD-----PYPPPPG 1420
Query: 1335 SNASCAAAPCLHGGSCRPAPL-APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQ 1393
A R AP AP F + GP E+ A AP R P
Sbjct: 1421 PFAR------------REAPYGAPRFDMPDFEDDGGPYGESEAPAPP-GPGTRWP----Y 1463
Query: 1394 AKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRL--FNNSRC 1442
R +R E P +GG + S+ +P+ + EA +C L N RC
Sbjct: 1464 RSRDTRRSFPEPEEPP---EGGSYAGSLAEPYEELEAEECGILDGCTNGRC 1511
Score = 268 bits (685), Expect = 5e-71
Identities = 292/1031 (28%), Positives = 390/1031 (37%), Gaps = 181/1031 (17%)
Query: 43 CLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHS--------GPC--- 87
C D CA GGRC C+CP G++ + + C S GPC
Sbjct: 318 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSR--SSCISQHVISEAKGPCFRV 375
Query: 88 AGRGVCQSSVVAGTARFSCRCPRGFR--GPDCSLPDPCLSSPCAHGAR--CSVGPDGRFL 143
G C ++ + C C R + G C L P S G R C GP +
Sbjct: 376 LRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSE----GFREICPAGPGYHYS 431
Query: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE-------N 196
S Y R + + +P T + G P P E
Sbjct: 432 AS-DLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFL----PTHRLEPRPEPRPDPRPG 486
Query: 197 PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN 256
P +P P G +SG C+ N C G C+ +
Sbjct: 487 PELPLPSIPAWTGPEIPESGP-----------SSGMCQRNPQVC------GPGRCISRPS 529
Query: 257 TYNCQCPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-TGESC 311
Y C C + G C DVDEC+ P C G C N+ G CVC G+ G
Sbjct: 530 GYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 587
Query: 312 SQ--NIDDC--ATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNP--CH 361
++ ++D+C C G C + SF C CP G G C D C +P C
Sbjct: 588 AECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 646
Query: 362 EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR 421
A C P + R C CP GF G AC++DVDEC+ PC GRC NT GSF C C
Sbjct: 647 RGA-CKNLPGSFR--CVCPAGFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPA 702
Query: 422 GYT----GPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAGF----TGTYCEVDIDE 472
G+ G C+ DV+EC S P C + G F C+C GF G+ CE D+DE
Sbjct: 703 GFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDE 760
Query: 473 CQSSPCVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECAS--TPCRNGAKCVDQPD 527
C++ G C + F C TCPSG C DVDEC+S PC C +
Sbjct: 761 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEG 819
Query: 528 GYECRCAEGFE------GTLCDRNV----DDCSPDPCHHGRCVDGIASFSCACAPGYT-- 575
+ C CA G+ G D N D C P HG C++ SF+C CAPGY
Sbjct: 820 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP----HGECLNTDGSFACTCAPGYRPG 875
Query: 576 --GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTG----VNCEVNIDDCASNP- 628
G C VDEC + G C + + C CP G +C +++D+C
Sbjct: 876 PRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGP 933
Query: 629 --CTFGVCRDGINRYDCV--CQPGF-TGP--LCNVEINECAS---SPCGEGGSCVDGENG 678
C C + Y CV C PG+ GP C+ +++EC CG C +
Sbjct: 934 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICG-AQRCENTPGS 991
Query: 679 FRCL--CPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGWSGPR 728
+RC C PG P P C + C +H +C + PG F+C+C+ G+ G R
Sbjct: 992 YRCTPACDPGYQPT----PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1047
Query: 729 CSQSLAR-DACES-QPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG--- 783
+ + CE+ Q C + F C CP + + C P G
Sbjct: 1048 DGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD-PMTGRCVPPRTSAGTFP 1106
Query: 784 GRCESAPGQ--LPVCSCP-----------QGWQGPRCQQDVDECAGPAPCGPHGICTNLA 830
G AP LP P QG G ++ + A P C + + N+
Sbjct: 1107 GSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACD-NILARNVT 1165
Query: 831 GSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGS-CQDGVGSFSCSCLPGFAGPRCARDVD 889
C G G C I C S C G G + S RDVD
Sbjct: 1166 WQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGRGYLAPS-----GDLSLRRDVD 1218
Query: 890 ECL---SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ----DLPDCSPSS-CFNGGTCVD 941
EC C G C + ++C C GY +H ++ D +C+ GG CV+
Sbjct: 1219 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGRCVN 1277
Query: 942 GVNSFSCLCRP 952
V S+ C C P
Sbjct: 1278 TVGSYHCTCEP 1288
Score = 266 bits (680), Expect = 2e-70
Identities = 297/1046 (28%), Positives = 404/1046 (38%), Gaps = 224/1046 (21%)
Query: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
P GK +LC L CH +C P C CPP F G C A
Sbjct: 108 PAGKAPVLCPLI-------CHNGGVC-VKPDR----CLCPPDFAGKFCQLHSSGARPPAP 155
Query: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN------------ECLSGPCRNQATCLD 448
L R V T + V E +SGP +
Sbjct: 156 AVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADA--E 213
Query: 449 RIGQFTCICMAGFTGTYCEVDIDECQSSPCVNG-------GVCKDRVNGFSCTCPSG--- 498
+ + A Y + QS+P +G G C + G C P
Sbjct: 214 AVARAEAAARAEAAAPYTVL----AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLR 269
Query: 499 -----FSGSTCQLDVDECASTPCRNG-AKCVDQPDGYECRCAEGFEGT--LCDRNVDDCS 550
G+ V +C R G ++ V PDG C GFE C+ +VD+C+
Sbjct: 270 TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNGSCE-DVDECA 325
Query: 551 PDP-CHHGRCVDGIASFSCACAPGY----TGTRCESQ--VDECRSQPC----RHGGKCLD 599
C HG C + ++C C G+ + + C SQ + E + PC R GG L
Sbjct: 326 TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKG-PCFRVLRDGGCSLP 384
Query: 600 L---VDKYLCRCP--SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 654
+ + K +C C G C++ C FG +G R C PG+
Sbjct: 385 ILRNITKQICCCSRVGKAWGRGCQL----CP----PFG--SEGF-REICPAGPGYHYSAS 433
Query: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP-------------------- 694
++ N + P G+ V L P +LP P
Sbjct: 434 DLRYN---TRPLGQEPPRVS-------LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP 483
Query: 695 --------PSHP----------------CAHEP--CSHGICYDAPGGFRCVCEPGWS-GP 727
PS P C P C G C P G+ C C+ G+ P
Sbjct: 484 RPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSP 543
Query: 728 RCSQSLARDACE--SQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPC--TPNP 779
+ ++ + D C PC A G C + F C C PG + +C + C P P
Sbjct: 544 QGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 602
Query: 780 CEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECA-GPAPCGPHGICTNLAGSFS 834
C+ GRCE+ PG +C CP G+Q G C QDVDEC P CG G C NL GSF
Sbjct: 603 CDL-GRCENTPGSF-LCVCPAGYQAAPHGASC-QDVDECTQSPGLCG-RGACKNLPGSFR 658
Query: 835 CTCHGGYTGPSCDQDINDC--DPNPCLNGGSCQDGVGSFSCSCLPGF--AGPRC-ARDVD 889
C C G+ G +C++D+++C +P PC G C + GSF C+C GF GP +DVD
Sbjct: 659 CVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 717
Query: 890 ECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGV 943
EC + PC G C + SF C CP G+ G CE D+ +C G CV+
Sbjct: 718 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSP 776
Query: 944 NSFSCLCRPGYTGAHCQH----EADPCLS--RPCLHGGVCSAAHPGFRCTCLESFTGPQ- 996
SF C P +G H + D C S PC G C+ FRC+C + P
Sbjct: 777 GSFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 834
Query: 997 ----CQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVR 1050
C + + C G C+ T G++ C C PG+ L E +
Sbjct: 835 RPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE----- 889
Query: 1051 LEQLCQAGGQCVDEDSSHYCVCPEG-RTGSHCEQ--EVDPCLAQ-PCQHGG-TCRGYMGG 1105
E LCQ+ G C + D S C+CP G R G +VD C + P G C G
Sbjct: 890 -EDLCQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGS 947
Query: 1106 YMC--ECLPGYNG--DNCEDDVDECASQPCQHGGS--CIDLVARYLC--SCPPG---TLG 1154
Y C +C PGY+ + DDVDEC + G+ C + Y C +C PG T G
Sbjct: 948 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 1007
Query: 1155 VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLR----CEADINECR 1210
C+ + D+C + C + C +L G F+C C GY G R C D+NEC
Sbjct: 1008 GGCQ-DVDEC------RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECE 1059
Query: 1211 S--GACHAAHTRDCLQDPGGGFRCLC 1234
+ G C AA ++ G F C+C
Sbjct: 1060 TLQGVCGAA----LCENVEGSFLCVC 1081
Score = 263 bits (671), Expect = 2e-69
Identities = 325/1112 (29%), Positives = 436/1112 (39%), Gaps = 223/1112 (20%)
Query: 486 DRVNGFSCTCPSGFS--GSTCQLDVDECASTP-CRNGAKCVDQPDGYECRCAEGFEGTLC 542
+RV+ CP+GF +C+ DVDECA+ C++G +C + GY C C +GF L
Sbjct: 298 ERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF---LL 352
Query: 543 DRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC----RHGGKCL 598
D + C I+ + A G PC R GG L
Sbjct: 353 DSSRSSC-------------ISQHVISEAKG----------------PCFRVLRDGGCSL 383
Query: 599 DL---VDKYLCRCP--SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPL 653
+ + K +C C G C++ C FG +G R C PG+
Sbjct: 384 PILRNITKQICCCSRVGKAWGRGCQL----CP----PFG--SEGF-REICPAGPGYHYSA 432
Query: 654 CNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP-----PSHPCAHEPCSHGI 708
++ N + P G+ V L P +LP P P+H P
Sbjct: 433 SDLRYN---TRPLGQEPPRVS-------LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 482
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQS-LARDACESQPCRAG-GTCSSDGMGFHCTCPPGV-- 764
P P W+GP +S + C+ P G G C S G+ C C G
Sbjct: 483 PRPGP-ELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRL 541
Query: 765 --QGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQQ--DVDECAGP 817
QG +C + C P PC GRCE++PG C C G++ GPR + DVDEC
Sbjct: 542 SPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFR-CVCGPGFRAGPRAAECLDVDECHRV 599
Query: 818 APCGPHGICTNLAGSFSCTCHGGYT----GPSCDQDINDCDPNPCLNG-GSCQDGVGSFS 872
P G C N GSF C C GY G SC QD+++C +P L G G+C++ GSF
Sbjct: 600 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSPGLCGRGACKNLPGSFR 658
Query: 873 CSCLPGFAGPRCARDVDECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLP 926
C C GF G C DVDEC PCGPG C + SF C CP G+ G C QD+
Sbjct: 659 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVD 717
Query: 927 DC--SPSSCFNGGTCVDGVNSFSCLC----RPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
+C SP C G C + SF C+C +P G+ C+ + D C + G C +
Sbjct: 718 ECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 775
Query: 981 HPGFRCTCLES---FTGPQCQTLVDWCS--RQPCQNGGRCVQT-GAY-CLCPPGWSGRLC 1033
F+C S +C T VD CS PC G C T G++ C C PG+ R
Sbjct: 776 PGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY--RAP 832
Query: 1034 DIRSLPCREAAAQIGVRLE-QLCQAGGQCVDEDSSHYCVCP----EGRTGSHCEQEVDPC 1088
R PC A + LE C G+C++ D S C C G G+ C +VD C
Sbjct: 833 SGRPGPC----ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDEC 887
Query: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGD----NCEDDVDECASQPCQHGGS--CIDLVA 1142
+ G C G + C C PG+ +C DVDEC + GS C +
Sbjct: 888 SEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPG 946
Query: 1143 RYLC--SCPPGTLG---VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT--CPP 1195
Y C C PG C+ + D+C + GP C + G +RCT C P
Sbjct: 947 SYRCVRDCDPGYHAGPEGTCD-DVDEC-----QEYGPEICGAQRCENTPGSYRCTPACDP 1000
Query: 1196 GY---TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
GY G C+ D++ECR+ + AH Q+ G F+CLC G+ G R +
Sbjct: 1001 GYQPTPGGGCQ-DVDECRNRSFCGAHA--VCQNLPGSFQCLCDQGYEGAR--------DG 1049
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
+ C +C G G CE V S CP P + P R
Sbjct: 1050 RHCVDVNECETLQGVCGAAL-------------CENVEGSFL-CVCP-NSPEEFDPMTGR 1094
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGP-- 1370
C P +G +FPGS P A A+P L P P P QG G
Sbjct: 1095 CVPPRTSAG----TFPGSQPQA-----PASPVLPARP--PPPPLPRRPSTPRQGPVGSGR 1143
Query: 1371 -RCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC- 1428
C AAP+ + Q C C + G GW G C + +QC
Sbjct: 1144 RECYFDTAAPDACDNILARNVTW------QEC---CCTVGEGW-GSGCRI------QQCP 1187
Query: 1429 --EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCN--------PVYEKYCAD- 1477
E + L + R A S L + D R++ C P Y YC++
Sbjct: 1188 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1247
Query: 1478 ---HFADGRC--DQGCNTEECGWDGLDCASEV 1504
H C + C EE +G C + V
Sbjct: 1248 YYYHTQRLECIDNDECADEEPACEGGRCVNTV 1279
Score = 250 bits (639), Expect = 1e-65
Identities = 310/1099 (28%), Positives = 401/1099 (36%), Gaps = 249/1099 (22%)
Query: 48 PCANGGRCTQLPSREAACLCPPGW-VGER---CQLEDPCHS-GPCAGRGVCQSSVVAGTA 102
PCA G RC P C+C PG+ G R C D CH P G C+++
Sbjct: 560 PCAPG-RCENSPG-SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENT----PG 613
Query: 103 RFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
F C CP G++ G C D C SP C GA C P G F C CP G++G +C
Sbjct: 614 SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE 671
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPC--------APSPCRN 208
DVDEC P G C NT GSF C CPAG+ P PC +P PC
Sbjct: 672 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS---RGPGAPCQDVDECARSPPPCTY 728
Query: 209 GGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPP 264
G G ++ C C GF+ G CE +VD+C H G CV+ ++ C+ P
Sbjct: 729 GRCENTEG--SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCP 785
Query: 265 E----WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES-----CSQNI 315
G+ CT DVDEC C G C NT G C C G+ S C+ ++
Sbjct: 786 SGHHLHRGR-CT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DV 842
Query: 316 DDCATA-VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNPCHEDAICDTNP 370
++C CF C + SF C C G G C D C + IC TN
Sbjct: 843 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TN- 900
Query: 371 VNGRAICTCPPGFTGG---ACDQDVDECSIGANPCEHLGRCVNTQGSFLC--QCGRGY-T 424
+G C CPPG G A DVDEC RC N+ GS+ C C GY
Sbjct: 901 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 960
Query: 425 GPR--CETDVNECLS-GP--CRNQATCLDRIGQFTC--ICMAGF---TGTYCEVDIDECQ 474
GP C+ DV+EC GP C Q C + G + C C G+ G C+ D+DEC+
Sbjct: 961 GPEGTCD-DVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECR 1017
Query: 475 S-SPCVNGGVCKDRVNGFSCTCPSGFSGST----CQLDVDECASTPCRNGAKCVDQPDG- 528
+ S C VC++ F C C G+ G+ C +DV+EC + GA + +G
Sbjct: 1018 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGS 1076
Query: 529 YECRC--------------------AEGFEGTLCDRNVDDCSP----------------- 551
+ C C A F G+ P
Sbjct: 1077 FLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1136
Query: 552 DPCHHGR---CVDGIASFSC--ACAPGYTGTRCESQVDE-----CRSQPCRHGGKCLDLV 601
P GR D A +C A T C V E CR Q C
Sbjct: 1137 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETA---- 1192
Query: 602 DKYLCRCPSG------TTGVNCEVNIDDC---ASNPCTFGVCRDGINRYDCVCQPGF--- 649
+Y CP G + ++ ++D+C C GVC + Y C C G+
Sbjct: 1193 -EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYH 1251
Query: 650 TGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS-HPCAHEPCSH- 706
T L ++ +ECA P EGG CV+ + C C PPL L S C
Sbjct: 1252 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE----PPLVLDGSQRRCVSNESQSL 1307
Query: 707 ----GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPP 762
G+C+ G VC S PR L R A ++ C G + G C P
Sbjct: 1308 DDNLGVCWQEVGA-DLVC----SHPR----LDRQATYTECCCLYG----EAWGMDCALCP 1354
Query: 763 GVQGRQ----CELLSPCTPNPCEHGG---------------------------------R 785
C +L P +P GG
Sbjct: 1355 AQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDP 1414
Query: 786 CESAPGQLPVCSCPQG---WQGPRCQQD---VDECAGPAPCGPHGICTNLAGSFSCTCHG 839
PG P G + P + D E PAP GP
Sbjct: 1415 YPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGP----------------- 1457
Query: 840 GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-LSNPCGP 898
G P +D P P +G GS++ S A P + +EC + + C
Sbjct: 1458 GTRWPYRSRDTRRSFPEP----EEPPEG-GSYAGS----LAEPYEELEAEECGILDGCTN 1508
Query: 899 GTCTDHVASFTCTCPPGY----GGFHC----EQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
G C FTC C GY C E D + + C N C++ SF C+C
Sbjct: 1509 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN-ARCLNTDGSFRCIC 1567
Query: 951 RPGYTGAHCQHEADPCLSR 969
RPG+ H H P R
Sbjct: 1568 RPGFAPTHQPHHCAPARPR 1586
Score = 240 bits (612), Expect = 1e-62
Identities = 279/990 (28%), Positives = 370/990 (37%), Gaps = 203/990 (20%)
Query: 570 CAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
C G C S + R+Q CR G + D LC S G + V+ D
Sbjct: 252 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLC---SERLGNSERVSAPD---- 304
Query: 628 PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
G C G R + C+ +++ECA+ + G C + G+ C+CP G
Sbjct: 305 ----GPCPTGFERVNGSCE----------DVDECATGGRCQHGECANTRGGYTCVCPDGF 350
Query: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGG-FRCVCEPGWSGPRCSQSLARDACESQPCRAG 746
L L S S + +A G FR + + G S P + C S+ +A
Sbjct: 351 L----LDSSRSSC---ISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW 403
Query: 747 G----TCSSDGM-GFHCTCP--PGVQGRQCEL--------------------LSPCTPNP 779
G C G GF CP PG +L P T P
Sbjct: 404 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRP 463
Query: 780 C-----------EHGGRCESAPG-QLPVCSCPQGWQGPRCQQDVDECA----GPAPCGPH 823
R + PG +LP+ S P W GP + P CGP
Sbjct: 464 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIP-AWTGPEIPESGPSSGMCQRNPQVCGP- 521
Query: 824 GICTNLAGSFSCTCHGGY----TGPSCDQDINDCD--PNPCLNGGSCQDGVGSFSCSCLP 877
G C + ++C C G+ G C D+++C P PC G C++ GSF C C P
Sbjct: 522 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGP 579
Query: 878 GF-AGPRCAR--DVDEC--LSNPCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDC 928
GF AGPR A DVDEC + PC G C + SF C CP GY G C QD+ +C
Sbjct: 580 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC 638
Query: 929 --SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGFR 985
SP C G C + SF C+C G+ G+ C+ + D C P G G C F
Sbjct: 639 TQSPGLC-GRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFH 697
Query: 986 CTCLESF----TGPQCQTLVDWCSRQ--PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRS 1037
C C F G CQ VD C+R PC GRC T G++ C+CP G+
Sbjct: 698 CACPAGFRSRGPGAPCQD-VDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC 755
Query: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC-VCPEGR--TGSHCEQEVDPCL--AQP 1092
E L G +CV+ S C CP G C +VD C A P
Sbjct: 756 EDVDECE-------NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPP 807
Query: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCED----DVDECASQP-CQHGGSCIDLVARYLCS 1147
C G C G + C C PGY + DV+EC C G C++ + C+
Sbjct: 808 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACT 867
Query: 1148 CP----PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG---L 1200
C PG G C ++ D+C S +G C + G F C CPPG+ L
Sbjct: 868 CAPGYRPGPRGASC-LDVDEC-------SEEDLCQSGICTNTDGSFECICPPGHRAGPDL 919
Query: 1201 RCEADINECRSGACHAAHTRDCLQDPGGGFRCL--CHAGF-SGPR--CQTV-----LSP- 1249
D++ECR ++ C P G +RC+ C G+ +GP C V P
Sbjct: 920 ASCLDVDECRERGPALCGSQRCENSP-GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 978
Query: 1250 -CESQPCQH---GGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQ 1305
C +Q C++ +C P+ PG QP G C+ V C CQ
Sbjct: 979 ICGAQRCENTPGSYRCTPACDPG---------YQPTPGGGCQDVDECRNRSFCGAHAVCQ 1029
Query: 1306 QTPRGPRCACPPGLSGP----------SCRSFPGSPPGASNASCAAAPC--LHGGSCRPA 1353
P +C C G G C + G C AA C + G
Sbjct: 1030 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG--------VCGAALCENVEGSFLCVC 1081
Query: 1354 PLAP------FFRC----ACAQGWTGPRCEAPA-----AAPEVSEEPRCPRAACQAKRGD 1398
P +P RC A + G + +APA A P PR P Q G
Sbjct: 1082 PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1141
Query: 1399 QRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
R REC D D L+ W++C
Sbjct: 1142 GR--RECYFDTAAPDACDNILARNVTWQEC 1169
Score = 56.2 bits (134), Expect = 4e-07
Identities = 37/101 (36%), Positives = 46/101 (45%), Gaps = 21/101 (20%)
Query: 108 CPRGFRGPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCS---------------CPPGY 150
C R RG +C+ P P L + C GA + G LCS CP G+
Sbjct: 252 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 311
Query: 151 Q--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY 189
+ SC DVDEC G C+HG C NT G + C CP G+
Sbjct: 312 ERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 350
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/77 (38%), Positives = 34/77 (44%), Gaps = 23/77 (29%)
Query: 2 GPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSR 61
GPG RG RRR P P PV PL+ C NGG C + P R
Sbjct: 92 GPGGRGLLRRRPPQRAPAGKAPVLC-PLI------------------CHNGGVCVK-PDR 131
Query: 62 EAACLCPPGWVGERCQL 78
CLCPP + G+ CQL
Sbjct: 132 ---CLCPPDFAGKFCQL 145
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1179 NGTCVDLVGGFRCTCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRC 1232
NG CV + GF C C GY T + C DINEC A CL + G FRC
Sbjct: 1508 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCL-NTDGSFRC 1565
Query: 1233 LCHAGFS 1239
+C GF+
Sbjct: 1566 ICRPGFA 1572
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 13/95 (13%)
Query: 618 EVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINEC----ASSPCGE 668
E+ ++C + CT G C + C C G+ T C V+INEC A+SP
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1552
Query: 669 GGSCVDGENGFRCLCPPGSLP---PLCLPPSHPCA 700
C++ + FRC+C PG P P P+ P A
Sbjct: 1553 NARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1587
Score = 36.6 bits (83), Expect = 0.29
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 10/83 (12%)
Query: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGP 1174
E + +EC G C+ + + C C G T +INE D + P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEA----ASP 1549
Query: 1175 RCLHNGTCVDLVGGFRCTCPPGY 1197
C+ N C++ G FRC C PG+
Sbjct: 1550 LCV-NARCLNTDGSFRCICRPGF 1571
Score = 33.1 bits (74), Expect = 3.3
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 3/27 (11%)
Query: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFC 271
C NGG CV C CPP++ G+FC
Sbjct: 120 CHNGGVCV---KPDRCLCPPDFAGKFC 143
Score = 33.1 bits (74), Expect = 3.3
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 1082 EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE---DDVDEC----ASQPCQHG 1134
E E + C G C G+ C C GY D D++EC A+ P
Sbjct: 1494 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1553
Query: 1135 GSCIDLVARYLCSCPPG 1151
C++ + C C PG
Sbjct: 1554 ARCLNTDGSFRCICRPG 1570
Score = 32.3 bits (72), Expect = 5.6
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 3/58 (5%)
Query: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE 1082
P G GR R P R A + V +C GG CV D C+CP G C+
Sbjct: 90 PRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDR---CLCPPDFAGKFCQ 144
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 305 bits (782), Expect = 3e-82
Identities = 307/1021 (30%), Positives = 395/1021 (38%), Gaps = 227/1021 (22%)
Query: 2 GPG----ARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQ 57
GPG A R RP+ PP + L + P A P P R
Sbjct: 462 GPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEP-RPDP 520
Query: 58 LPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
P E P W G SGP +G +CQ R P
Sbjct: 521 RPGPELPLPSIPAWTGPEIP-----ESGPSSG--MCQ------------------RNPQV 555
Query: 118 SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGGT 173
P C+S P + C+C G+ QG C DVDECR P G
Sbjct: 556 CGPGRCISRPSG------------YTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR 602
Query: 174 CLNTPGSFRCQCPAGY-TGPLCENPAVPC--------APSPCRNGGTCRQSGDLTYDCAC 224
C N+PGSFRC C G+ GP A C P PC G G ++ C C
Sbjct: 603 CENSPGSFRCVCGPGFRAGP----RAAECLDVDECHRVPPPCDLGRCENTPG--SFLCVC 656
Query: 225 LPGFE----GQNCEVNVDDCPGHRCLNG-GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ 279
G++ G +C+ +VD+C L G G C + ++ C CP + G C EDVDEC
Sbjct: 657 PAGYQAAPHGASCQ-DVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECA 715
Query: 280 LQPNACHNGGTCFNTLGGHSCVCVNGW----TGESCSQNIDDCATA--VCFHGATCHDRV 333
+P C G C NT G C C G+ G C Q++D+CA + C +G C +
Sbjct: 716 QEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVDECARSPPPCTYG-RCENTE 772
Query: 334 ASFYCACPMG----KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC-TCPPG--FTGG 386
SF C CPMG G C D C ++ C +P G C TCP G G
Sbjct: 773 GSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQECVNSP--GSFQCRTCPSGHHLHRG 830
Query: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE----TDVNECLSGP-CR 441
C DVDECS GA PC G C NT+GSF C C GY P DVNECL G C
Sbjct: 831 RC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCF 889
Query: 442 NQATCLDRIGQFTCICMAGF----TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
CL+ G F C C G+ G C +D+DEC G+C + F C CP
Sbjct: 890 PHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPP 948
Query: 498 GFSG----STCQLDVDECAST-PCRNGA-KCVDQPDGYEC--RCAEGF----EGTLCDRN 545
G ++C LDVDEC P G+ +C + P Y C C G+ EGT CD +
Sbjct: 949 GHRAGPDLASC-LDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGT-CD-D 1005
Query: 546 VDDC---SPDPCHHGRCVDGIASFSC--ACAPGY---TGTRCESQVDECRSQP-CRHGGK 596
VD+C P+ C RC + S+ C AC PGY G C+ VDECR++ C
Sbjct: 1006 VDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAV 1064
Query: 597 CLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNV 656
C +L + C C G G RDG + C V
Sbjct: 1065 CQNLPGSFQCLCDQGYEG-------------------ARDGRH---C------------V 1090
Query: 657 EINECAS--SPCGEGGSCVDGENGFRCLCP--PGSLPPL---CLPPSHPCAHEPCSHGIC 709
++NEC + CG C + E F C+CP P P+ C+PP P S
Sbjct: 1091 DVNECETLQGVCG-AALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQA 1149
Query: 710 YDAP-----------------------GGFRCVCEPGWSGP-RCSQSLARDACESQPCRA 745
+P G R C + P C LAR+ + C
Sbjct: 1150 PASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCCT 1209
Query: 746 GGTCSSDGMGFHCTCP--PGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
G +G G C PG + + + L C HG + G L +
Sbjct: 1210 VG----EGWGSGCRIQQCPGTETAEYQSL-------CPHGRGYLAPSGDLSL-------- 1250
Query: 804 GPRCQQDVDECA--GPAPCGPHGICTNLAGSFSCTCHGGY----TGPSCDQDINDCDPNP 857
++DVDEC C G+C N A +SC C GY C + D P
Sbjct: 1251 ----RRDVDECQLFRDQVC-KSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEP 1305
Query: 858 CLNGGSCQDGVGSFSCSCLPGF----AGPRCARDVDECLSNPCGPGTCTDHV-ASFTCTC 912
GG C + VGS+ C+C P + RC + + L + G C V A C+
Sbjct: 1306 ACEGGRCVNTVGSYHCTCEPPLVLDGSQRRCVSNESQSLDD--NLGVCWQEVGADLVCSH 1363
Query: 913 P 913
P
Sbjct: 1364 P 1364
Score = 300 bits (769), Expect = 8e-81
Identities = 388/1371 (28%), Positives = 501/1371 (36%), Gaps = 341/1371 (24%)
Query: 249 GTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-- 306
G C G N C EDVDEC H G C NT GG++CVC +G+
Sbjct: 342 GPCPTGFERVNGSC----------EDVDECATGGRCQH--GECANTRGGYTCVCPDGFLL 389
Query: 307 --TGESC-SQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHED 363
+ SC SQ++ A CF D S + K C C
Sbjct: 390 DSSRSSCISQHVISEAKGPCFR--VLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQ-- 445
Query: 364 AICDTNPVNG-RAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR- 421
+C G R IC PG+ A D + +G P R +Q L R
Sbjct: 446 -LCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEP----PRVSLSQPRTLPATSRP 500
Query: 422 --------------------------------GYTGPRCETDVNECLSGPCRNQ------ 443
+TGP E + SG C+
Sbjct: 501 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGP--EIPESGPSSGMCQRNPQVCGP 558
Query: 444 ATCLDRIGQFTCICMAGF----TGTYCEVDIDECQ--SSPCVNGGVCKDRVNGFSCTCPS 497
C+ R +TC C +GF GT C +D+DEC+ PC G C++ F C C
Sbjct: 559 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGP 616
Query: 498 GF----SGSTCQLDVDEC--ASTPCRNGAKCVDQPDGYECRCAEGFE----GTLCDRNVD 547
GF + C LDVDEC PC G +C + P + C C G++ G C ++VD
Sbjct: 617 GFRAGPRAAEC-LDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASC-QDVD 673
Query: 548 DC--SPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHG-GKCLDLVDKY 604
+C SP C G C + SF C C G+ G+ CE VDEC +P G G+C + +
Sbjct: 674 ECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSF 733
Query: 605 LCRCPSG----TTGVNCEVNIDDCASN--PCTFGVCRDGINRYDCVC----QPGFTGPLC 654
C CP+G G C+ ++D+CA + PCT+G C + + CVC QP G C
Sbjct: 734 HCACPAGFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSEC 792
Query: 655 N---------------------------------------VEINECASS--PCGEGGSCV 673
+++EC+S PCG G C
Sbjct: 793 EDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCT 852
Query: 674 DGENGFRCLCPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGW- 724
+ E FRC C PG P P PCA C HG C + G F C C PG+
Sbjct: 853 NTEGSFRCSCAPGYRAPSGRP--GPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYR 910
Query: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGG 784
GPR + L D C + G C++ F C CPPG + +L S + C G
Sbjct: 911 PGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGP-DLASCLDVDECRERG 969
Query: 785 -------RCESAPGQLP-VCSCPQGWQ-GPR-CQQDVDECA--GPAPCGPHGICTNLAGS 832
RCE++PG V C G+ GP DVDEC GP CG C N GS
Sbjct: 970 PALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR-CENTPGS 1028
Query: 833 FSCT--CHGGY---TGPSCDQDINDC-DPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
+ CT C GY G C QD+++C + + C CQ+ GSF C C G+ G R R
Sbjct: 1029 YRCTPACDPGYQPTPGGGC-QDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGR 1087
Query: 887 ---DVDEC--LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVD 941
DV+EC L CG C + SF C CP F P + G CV
Sbjct: 1088 HCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEF---------DPMT----GRCVP 1134
Query: 942 GVNSFSCLCRPGYTGAHCQHEADPCL-SRPCLHGGVCSAAHPGFRCTCLESFTGP-QCQT 999
S + G+ Q A P L +RP P T + G + +
Sbjct: 1135 PRTSAGT-----FPGSQPQAPASPVLPARP------PPPPLPRRPSTPRQGPVGSGRREC 1183
Query: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCP--PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA 1057
D + C N T C C GW G C I+ P E A + LC
Sbjct: 1184 YFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRIQQCPGTETA-----EYQSLCPH 1237
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA---QPCQHGGTCRGYMGGYMCECLPGY 1114
G + P G ++VD C Q C+ G C GY C C GY
Sbjct: 1238 G---------RGYLAPSGDLS--LRRDVDECQLFRDQVCK-SGVCVNTAPGYSCYCSNGY 1285
Query: 1115 ----NGDNCEDDVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPP 1169
C D+ DECA +P GG C++ V Y C+C P +
Sbjct: 1286 YYHTQRLECIDN-DECADEEPACEGGRCVNTVGSYHCTCEPPLV---------------- 1328
Query: 1170 LD-SGPRCLHN---------GTCVDLVGG-FRCTCPPGYTGLRCEADINECRSGACHAAH 1218
LD S RC+ N G C VG C+ P L +A EC C
Sbjct: 1329 LDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHP----RLDRQATYTEC----C---- 1376
Query: 1219 TRDCLQDPGGGFRC-LCHAGFSG---PRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFT 1274
CL G C LC A S C + P S P RP G GL +
Sbjct: 1377 ---CLYGEAWGMDCALCPAQDSDDFEALCNVLRPPAYSPP-------RPG---GFGLPYE 1423
Query: 1275 CHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGA 1334
+GP +G P Q P GP PP L P PP
Sbjct: 1424 -------YGP--------------DLGPPYQGLPYGPELYPPPALPYD-----PYPPPPG 1457
Query: 1335 SNASCAAAPCLHGGSCRPAPL-APFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQ 1393
A R AP AP F + GP E+ A AP R P
Sbjct: 1458 PFAR------------REAPYGAPRFDMPDFEDDGGPYGESEAPAPP-GPGTRWP----Y 1500
Query: 1394 AKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRL--FNNSRC 1442
R +R E P +GG + S+ +P+ + EA +C L N RC
Sbjct: 1501 RSRDTRRSFPEPEEPP---EGGSYAGSLAEPYEELEAEECGILDGCTNGRC 1548
Score = 268 bits (685), Expect = 5e-71
Identities = 292/1031 (28%), Positives = 390/1031 (37%), Gaps = 181/1031 (17%)
Query: 43 CLDGSPCANGGRCTQLPSREA----ACLCPPGWVGERCQLEDPCHS--------GPC--- 87
C D CA GGRC C+CP G++ + + C S GPC
Sbjct: 355 CEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSR--SSCISQHVISEAKGPCFRV 412
Query: 88 AGRGVCQSSVVAGTARFSCRCPRGFR--GPDCSLPDPCLSSPCAHGAR--CSVGPDGRFL 143
G C ++ + C C R + G C L P S G R C GP +
Sbjct: 413 LRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSE----GFREICPAGPGYHYS 468
Query: 144 CSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE-------N 196
S Y R + + +P T + G P P E
Sbjct: 469 AS-DLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFL----PTHRLEPRPEPRPDPRPG 523
Query: 197 PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN 256
P +P P G +SG C+ N C G C+ +
Sbjct: 524 PELPLPSIPAWTGPEIPESGP-----------SSGMCQRNPQVC------GPGRCISRPS 566
Query: 257 TYNCQCPPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW-TGESC 311
Y C C + G C DVDEC+ P C G C N+ G CVC G+ G
Sbjct: 567 GYTCACDSGFRLSPQGTRCI-DVDECRRVPPPCAPG-RCENSPGSFRCVCGPGFRAGPRA 624
Query: 312 SQ--NIDDC--ATAVCFHGATCHDRVASFYCACPMGKT----GLLCHLDDACVSNP--CH 361
++ ++D+C C G C + SF C CP G G C D C +P C
Sbjct: 625 AECLDVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG 683
Query: 362 EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR 421
A C P + R C CP GF G AC++DVDEC+ PC GRC NT GSF C C
Sbjct: 684 RGA-CKNLPGSFR--CVCPAGFRGSACEEDVDECAQEPPPCGP-GRCDNTAGSFHCACPA 739
Query: 422 GYT----GPRCETDVNECL-SGPCRNQATCLDRIGQFTCICMAGF----TGTYCEVDIDE 472
G+ G C+ DV+EC S P C + G F C+C GF G+ CE D+DE
Sbjct: 740 GFRSRGPGAPCQ-DVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDE 797
Query: 473 CQSSPCVNGGVCKDRVNGFSC-TCPSG--FSGSTCQLDVDECAS--TPCRNGAKCVDQPD 527
C++ G C + F C TCPSG C DVDEC+S PC C +
Sbjct: 798 CENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCT-DVDECSSGAPPCGPHGHCTNTEG 856
Query: 528 GYECRCAEGFE------GTLCDRNV----DDCSPDPCHHGRCVDGIASFSCACAPGYT-- 575
+ C CA G+ G D N D C P HG C++ SF+C CAPGY
Sbjct: 857 SFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFP----HGECLNTDGSFACTCAPGYRPG 912
Query: 576 --GTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTG----VNCEVNIDDCASNP- 628
G C VDEC + G C + + C CP G +C +++D+C
Sbjct: 913 PRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASC-LDVDECRERGP 970
Query: 629 --CTFGVCRDGINRYDCV--CQPGF-TGP--LCNVEINECAS---SPCGEGGSCVDGENG 678
C C + Y CV C PG+ GP C+ +++EC CG C +
Sbjct: 971 ALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQEYGPEICG-AQRCENTPGS 1028
Query: 679 FRCL--CPPGSLPPLCLPPSHPCAH-EPC-------SHGICYDAPGGFRCVCEPGWSGPR 728
+RC C PG P P C + C +H +C + PG F+C+C+ G+ G R
Sbjct: 1029 YRCTPACDPGYQPT----PGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGAR 1084
Query: 729 CSQSLAR-DACES-QPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHG--- 783
+ + CE+ Q C + F C CP + + C P G
Sbjct: 1085 DGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFD-PMTGRCVPPRTSAGTFP 1143
Query: 784 GRCESAPGQ--LPVCSCP-----------QGWQGPRCQQDVDECAGPAPCGPHGICTNLA 830
G AP LP P QG G ++ + A P C + + N+
Sbjct: 1144 GSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACD-NILARNVT 1202
Query: 831 GSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGS-CQDGVGSFSCSCLPGFAGPRCARDVD 889
C G G C I C S C G G + S RDVD
Sbjct: 1203 WQECCCTVGEGWGSGCR--IQQCPGTETAEYQSLCPHGRGYLAPS-----GDLSLRRDVD 1255
Query: 890 ECL---SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ----DLPDCSPSS-CFNGGTCVD 941
EC C G C + ++C C GY +H ++ D +C+ GG CV+
Sbjct: 1256 ECQLFRDQVCKSGVCVNTAPGYSCYCSNGYY-YHTQRLECIDNDECADEEPACEGGRCVN 1314
Query: 942 GVNSFSCLCRP 952
V S+ C C P
Sbjct: 1315 TVGSYHCTCEP 1325
Score = 266 bits (680), Expect = 2e-70
Identities = 297/1046 (28%), Positives = 404/1046 (38%), Gaps = 224/1046 (21%)
Query: 341 PMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGAN 400
P GK +LC L CH +C P C CPP F G C A
Sbjct: 145 PAGKAPVLCPLI-------CHNGGVC-VKPDR----CLCPPDFAGKFCQLHSSGARPPAP 192
Query: 401 PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN------------ECLSGPCRNQATCLD 448
L R V T + V E +SGP +
Sbjct: 193 AVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADA--E 250
Query: 449 RIGQFTCICMAGFTGTYCEVDIDECQSSPCVNG-------GVCKDRVNGFSCTCPSG--- 498
+ + A Y + QS+P +G G C + G C P
Sbjct: 251 AVARAEAAARAEAAAPYTVL----AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLR 306
Query: 499 -----FSGSTCQLDVDECASTPCRNG-AKCVDQPDGYECRCAEGFEGT--LCDRNVDDCS 550
G+ V +C R G ++ V PDG C GFE C+ +VD+C+
Sbjct: 307 TQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDG---PCPTGFERVNGSCE-DVDECA 362
Query: 551 PDP-CHHGRCVDGIASFSCACAPGY----TGTRCESQ--VDECRSQPC----RHGGKCLD 599
C HG C + ++C C G+ + + C SQ + E + PC R GG L
Sbjct: 363 TGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKG-PCFRVLRDGGCSLP 421
Query: 600 L---VDKYLCRCP--SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 654
+ + K +C C G C++ C FG +G R C PG+
Sbjct: 422 ILRNITKQICCCSRVGKAWGRGCQL----CP----PFG--SEGF-REICPAGPGYHYSAS 470
Query: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP-------------------- 694
++ N + P G+ V L P +LP P
Sbjct: 471 DLRYN---TRPLGQEPPRVS-------LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDP 520
Query: 695 --------PSHP----------------CAHEP--CSHGICYDAPGGFRCVCEPGWS-GP 727
PS P C P C G C P G+ C C+ G+ P
Sbjct: 521 RPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSP 580
Query: 728 RCSQSLARDACE--SQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPC--TPNP 779
+ ++ + D C PC A G C + F C C PG + +C + C P P
Sbjct: 581 QGTRCIDVDECRRVPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPP 639
Query: 780 CEHGGRCESAPGQLPVCSCPQGWQ----GPRCQQDVDECA-GPAPCGPHGICTNLAGSFS 834
C+ GRCE+ PG +C CP G+Q G C QDVDEC P CG G C NL GSF
Sbjct: 640 CDL-GRCENTPGSF-LCVCPAGYQAAPHGASC-QDVDECTQSPGLCG-RGACKNLPGSFR 695
Query: 835 CTCHGGYTGPSCDQDINDC--DPNPCLNGGSCQDGVGSFSCSCLPGF--AGPRC-ARDVD 889
C C G+ G +C++D+++C +P PC G C + GSF C+C GF GP +DVD
Sbjct: 696 CVCPAGFRGSACEEDVDECAQEPPPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVD 754
Query: 890 ECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDGV 943
EC + PC G C + SF C CP G+ G CE D+ +C G CV+
Sbjct: 755 ECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSP 813
Query: 944 NSFSCLCRPGYTGAHCQH----EADPCLS--RPCLHGGVCSAAHPGFRCTCLESFTGPQ- 996
SF C P +G H + D C S PC G C+ FRC+C + P
Sbjct: 814 GSFQCRTCP--SGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG 871
Query: 997 ----CQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVR 1050
C + + C G C+ T G++ C C PG+ L E +
Sbjct: 872 RPGPCADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSE----- 926
Query: 1051 LEQLCQAGGQCVDEDSSHYCVCPEG-RTGSHCEQ--EVDPCLAQ-PCQHGG-TCRGYMGG 1105
E LCQ+ G C + D S C+CP G R G +VD C + P G C G
Sbjct: 927 -EDLCQS-GICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGS 984
Query: 1106 YMC--ECLPGYNG--DNCEDDVDECASQPCQHGGS--CIDLVARYLC--SCPPG---TLG 1154
Y C +C PGY+ + DDVDEC + G+ C + Y C +C PG T G
Sbjct: 985 YRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPG 1044
Query: 1155 VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLR----CEADINECR 1210
C+ + D+C + C + C +L G F+C C GY G R C D+NEC
Sbjct: 1045 GGCQ-DVDEC------RNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECE 1096
Query: 1211 S--GACHAAHTRDCLQDPGGGFRCLC 1234
+ G C AA ++ G F C+C
Sbjct: 1097 TLQGVCGAA----LCENVEGSFLCVC 1118
Score = 263 bits (671), Expect = 2e-69
Identities = 325/1112 (29%), Positives = 436/1112 (39%), Gaps = 223/1112 (20%)
Query: 486 DRVNGFSCTCPSGFS--GSTCQLDVDECASTP-CRNGAKCVDQPDGYECRCAEGFEGTLC 542
+RV+ CP+GF +C+ DVDECA+ C++G +C + GY C C +GF L
Sbjct: 335 ERVSAPDGPCPTGFERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF---LL 389
Query: 543 DRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPC----RHGGKCL 598
D + C I+ + A G PC R GG L
Sbjct: 390 DSSRSSC-------------ISQHVISEAKG----------------PCFRVLRDGGCSL 420
Query: 599 DL---VDKYLCRCP--SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPL 653
+ + K +C C G C++ C FG +G R C PG+
Sbjct: 421 PILRNITKQICCCSRVGKAWGRGCQL----CP----PFG--SEGF-REICPAGPGYHYSA 469
Query: 654 CNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP-----PSHPCAHEPCSHGI 708
++ N + P G+ V L P +LP P P+H P
Sbjct: 470 SDLRYN---TRPLGQEPPRVS-------LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPD 519
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQS-LARDACESQPCRAG-GTCSSDGMGFHCTCPPGV-- 764
P P W+GP +S + C+ P G G C S G+ C C G
Sbjct: 520 PRPGP-ELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRL 578
Query: 765 --QGRQCELLSPC--TPNPCEHGGRCESAPGQLPVCSCPQGWQ-GPRCQQ--DVDECAGP 817
QG +C + C P PC GRCE++PG C C G++ GPR + DVDEC
Sbjct: 579 SPQGTRCIDVDECRRVPPPCA-PGRCENSPGSFR-CVCGPGFRAGPRAAECLDVDECHRV 636
Query: 818 APCGPHGICTNLAGSFSCTCHGGYT----GPSCDQDINDCDPNPCLNG-GSCQDGVGSFS 872
P G C N GSF C C GY G SC QD+++C +P L G G+C++ GSF
Sbjct: 637 PPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDECTQSPGLCGRGACKNLPGSFR 695
Query: 873 CSCLPGFAGPRCARDVDECLSN--PCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLP 926
C C GF G C DVDEC PCGPG C + SF C CP G+ G C QD+
Sbjct: 696 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC-QDVD 754
Query: 927 DC--SPSSCFNGGTCVDGVNSFSCLC----RPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
+C SP C G C + SF C+C +P G+ C+ + D C + G C +
Sbjct: 755 ECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 812
Query: 981 HPGFRCTCLES---FTGPQCQTLVDWCS--RQPCQNGGRCVQT-GAY-CLCPPGWSGRLC 1033
F+C S +C T VD CS PC G C T G++ C C PG+ R
Sbjct: 813 PGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGY--RAP 869
Query: 1034 DIRSLPCREAAAQIGVRLE-QLCQAGGQCVDEDSSHYCVCP----EGRTGSHCEQEVDPC 1088
R PC A + LE C G+C++ D S C C G G+ C +VD C
Sbjct: 870 SGRPGPC----ADVNECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDEC 924
Query: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGD----NCEDDVDECASQPCQHGGS--CIDLVA 1142
+ G C G + C C PG+ +C DVDEC + GS C +
Sbjct: 925 SEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL-DVDECRERGPALCGSQRCENSPG 983
Query: 1143 RYLC--SCPPGTLG---VLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCT--CPP 1195
Y C C PG C+ + D+C + GP C + G +RCT C P
Sbjct: 984 SYRCVRDCDPGYHAGPEGTCD-DVDEC-----QEYGPEICGAQRCENTPGSYRCTPACDP 1037
Query: 1196 GY---TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCES 1252
GY G C+ D++ECR+ + AH Q+ G F+CLC G+ G R +
Sbjct: 1038 GYQPTPGGGCQ-DVDECRNRSFCGAHA--VCQNLPGSFQCLCDQGYEGAR--------DG 1086
Query: 1253 QPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPR 1312
+ C +C G G CE V S CP P + P R
Sbjct: 1087 RHCVDVNECETLQGVCGAAL-------------CENVEGSFL-CVCP-NSPEEFDPMTGR 1131
Query: 1313 CACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGP-- 1370
C P +G +FPGS P A A+P L P P P QG G
Sbjct: 1132 CVPPRTSAG----TFPGSQPQA-----PASPVLPARP--PPPPLPRRPSTPRQGPVGSGR 1180
Query: 1371 -RCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQC- 1428
C AAP+ + Q C C + G GW G C + +QC
Sbjct: 1181 RECYFDTAAPDACDNILARNVTW------QEC---CCTVGEGW-GSGCRI------QQCP 1224
Query: 1429 --EALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCN--------PVYEKYCAD- 1477
E + L + R A S L + D R++ C P Y YC++
Sbjct: 1225 GTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNG 1284
Query: 1478 ---HFADGRC--DQGCNTEECGWDGLDCASEV 1504
H C + C EE +G C + V
Sbjct: 1285 YYYHTQRLECIDNDECADEEPACEGGRCVNTV 1316
Score = 250 bits (639), Expect = 1e-65
Identities = 310/1099 (28%), Positives = 401/1099 (36%), Gaps = 249/1099 (22%)
Query: 48 PCANGGRCTQLPSREAACLCPPGW-VGER---CQLEDPCHS-GPCAGRGVCQSSVVAGTA 102
PCA G RC P C+C PG+ G R C D CH P G C+++
Sbjct: 597 PCAPG-RCENSPG-SFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENT----PG 650
Query: 103 RFSCRCPRGFR----GPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
F C CP G++ G C D C SP C GA C P G F C CP G++G +C
Sbjct: 651 SFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE 708
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPC--------APSPCRN 208
DVDEC P G C NT GSF C CPAG+ P PC +P PC
Sbjct: 709 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS---RGPGAPCQDVDECARSPPPCTY 765
Query: 209 GGTCRQSGDLTYDCACLPGFE----GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPP 264
G G ++ C C GF+ G CE +VD+C H G CV+ ++ C+ P
Sbjct: 766 GRCENTEG--SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCP 822
Query: 265 E----WTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGES-----CSQNI 315
G+ CT DVDEC C G C NT G C C G+ S C+ ++
Sbjct: 823 SGHHLHRGR-CT-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCA-DV 879
Query: 316 DDCATA-VCFHGATCHDRVASFYCACP----MGKTGLLCHLDDACVSNPCHEDAICDTNP 370
++C CF C + SF C C G G C D C + IC TN
Sbjct: 880 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGIC-TN- 937
Query: 371 VNGRAICTCPPGFTGG---ACDQDVDECSIGANPCEHLGRCVNTQGSFLC--QCGRGY-T 424
+G C CPPG G A DVDEC RC N+ GS+ C C GY
Sbjct: 938 TDGSFECICPPGHRAGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHA 997
Query: 425 GPR--CETDVNECLS-GP--CRNQATCLDRIGQFTC--ICMAGF---TGTYCEVDIDECQ 474
GP C+ DV+EC GP C Q C + G + C C G+ G C+ D+DEC+
Sbjct: 998 GPEGTCD-DVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQ-DVDECR 1054
Query: 475 S-SPCVNGGVCKDRVNGFSCTCPSGFSGST----CQLDVDECASTPCRNGAKCVDQPDG- 528
+ S C VC++ F C C G+ G+ C +DV+EC + GA + +G
Sbjct: 1055 NRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGS 1113
Query: 529 YECRC--------------------AEGFEGTLCDRNVDDCSP----------------- 551
+ C C A F G+ P
Sbjct: 1114 FLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQ 1173
Query: 552 DPCHHGR---CVDGIASFSC--ACAPGYTGTRCESQVDE-----CRSQPCRHGGKCLDLV 601
P GR D A +C A T C V E CR Q C
Sbjct: 1174 GPVGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGWGSGCRIQQCPGTETA---- 1229
Query: 602 DKYLCRCPSG------TTGVNCEVNIDDC---ASNPCTFGVCRDGINRYDCVCQPGF--- 649
+Y CP G + ++ ++D+C C GVC + Y C C G+
Sbjct: 1230 -EYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYH 1288
Query: 650 TGPLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPS-HPCAHEPCSH- 706
T L ++ +ECA P EGG CV+ + C C PPL L S C
Sbjct: 1289 TQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCE----PPLVLDGSQRRCVSNESQSL 1344
Query: 707 ----GICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPP 762
G+C+ G VC S PR L R A ++ C G + G C P
Sbjct: 1345 DDNLGVCWQEVGA-DLVC----SHPR----LDRQATYTECCCLYG----EAWGMDCALCP 1391
Query: 763 GVQGRQ----CELLSPCTPNPCEHGG---------------------------------R 785
C +L P +P GG
Sbjct: 1392 AQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPELYPPPALPYDP 1451
Query: 786 CESAPGQLPVCSCPQG---WQGPRCQQD---VDECAGPAPCGPHGICTNLAGSFSCTCHG 839
PG P G + P + D E PAP GP
Sbjct: 1452 YPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGP----------------- 1494
Query: 840 GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-LSNPCGP 898
G P +D P P +G GS++ S A P + +EC + + C
Sbjct: 1495 GTRWPYRSRDTRRSFPEP----EEPPEG-GSYAGS----LAEPYEELEAEECGILDGCTN 1545
Query: 899 GTCTDHVASFTCTCPPGY----GGFHC----EQDLPDCSPSSCFNGGTCVDGVNSFSCLC 950
G C FTC C GY C E D + + C N C++ SF C+C
Sbjct: 1546 GRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN-ARCLNTDGSFRCIC 1604
Query: 951 RPGYTGAHCQHEADPCLSR 969
RPG+ H H P R
Sbjct: 1605 RPGFAPTHQPHHCAPARPR 1623
Score = 240 bits (612), Expect = 1e-62
Identities = 279/990 (28%), Positives = 370/990 (37%), Gaps = 203/990 (20%)
Query: 570 CAPGYTGTRCESQVDECRSQP--CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
C G C S + R+Q CR G + D LC S G + V+ D
Sbjct: 289 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLC---SERLGNSERVSAPD---- 341
Query: 628 PCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGS 687
G C G R + C+ +++ECA+ + G C + G+ C+CP G
Sbjct: 342 ----GPCPTGFERVNGSCE----------DVDECATGGRCQHGECANTRGGYTCVCPDGF 387
Query: 688 LPPLCLPPSHPCAHEPCSHGICYDAPGG-FRCVCEPGWSGPRCSQSLARDACESQPCRAG 746
L L S S + +A G FR + + G S P + C S+ +A
Sbjct: 388 L----LDSSRSSC---ISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW 440
Query: 747 G----TCSSDGM-GFHCTCP--PGVQGRQCEL--------------------LSPCTPNP 779
G C G GF CP PG +L P T P
Sbjct: 441 GRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRP 500
Query: 780 C-----------EHGGRCESAPG-QLPVCSCPQGWQGPRCQQDVDECA----GPAPCGPH 823
R + PG +LP+ S P W GP + P CGP
Sbjct: 501 SAGFLPTHRLEPRPEPRPDPRPGPELPLPSIP-AWTGPEIPESGPSSGMCQRNPQVCGP- 558
Query: 824 GICTNLAGSFSCTCHGGY----TGPSCDQDINDCD--PNPCLNGGSCQDGVGSFSCSCLP 877
G C + ++C C G+ G C D+++C P PC G C++ GSF C C P
Sbjct: 559 GRCISRPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVCGP 616
Query: 878 GF-AGPRCAR--DVDEC--LSNPCGPGTCTDHVASFTCTCPPGY----GGFHCEQDLPDC 928
GF AGPR A DVDEC + PC G C + SF C CP GY G C QD+ +C
Sbjct: 617 GFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC-QDVDEC 675
Query: 929 --SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGFR 985
SP C G C + SF C+C G+ G+ C+ + D C P G G C F
Sbjct: 676 TQSPGLC-GRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFH 734
Query: 986 CTCLESF----TGPQCQTLVDWCSRQ--PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRS 1037
C C F G CQ VD C+R PC GRC T G++ C+CP G+
Sbjct: 735 CACPAGFRSRGPGAPCQD-VDECARSPPPC-TYGRCENTEGSFQCVCPMGFQPNTAGSEC 792
Query: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC-VCPEGR--TGSHCEQEVDPCL--AQP 1092
E L G +CV+ S C CP G C +VD C A P
Sbjct: 793 EDVDECE-------NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC-TDVDECSSGAPP 844
Query: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCED----DVDECASQP-CQHGGSCIDLVARYLCS 1147
C G C G + C C PGY + DV+EC C G C++ + C+
Sbjct: 845 CGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGSFACT 904
Query: 1148 CP----PGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG---L 1200
C PG G C ++ D+C S +G C + G F C CPPG+ L
Sbjct: 905 CAPGYRPGPRGASC-LDVDEC-------SEEDLCQSGICTNTDGSFECICPPGHRAGPDL 956
Query: 1201 RCEADINECRSGACHAAHTRDCLQDPGGGFRCL--CHAGF-SGPR--CQTV-----LSP- 1249
D++ECR ++ C P G +RC+ C G+ +GP C V P
Sbjct: 957 ASCLDVDECRERGPALCGSQRCENSP-GSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPE 1015
Query: 1250 -CESQPCQH---GGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQ 1305
C +Q C++ +C P+ PG QP G C+ V C CQ
Sbjct: 1016 ICGAQRCENTPGSYRCTPACDPG---------YQPTPGGGCQDVDECRNRSFCGAHAVCQ 1066
Query: 1306 QTPRGPRCACPPGLSGP----------SCRSFPGSPPGASNASCAAAPC--LHGGSCRPA 1353
P +C C G G C + G C AA C + G
Sbjct: 1067 NLPGSFQCLCDQGYEGARDGRHCVDVNECETLQG--------VCGAALCENVEGSFLCVC 1118
Query: 1354 PLAP------FFRC----ACAQGWTGPRCEAPA-----AAPEVSEEPRCPRAACQAKRGD 1398
P +P RC A + G + +APA A P PR P Q G
Sbjct: 1119 PNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGS 1178
Query: 1399 QRCDRECNSPGCGWDGGDCSLSVGDPWRQC 1428
R REC D D L+ W++C
Sbjct: 1179 GR--RECYFDTAAPDACDNILARNVTWQEC 1206
Score = 56.2 bits (134), Expect = 4e-07
Identities = 37/101 (36%), Positives = 46/101 (45%), Gaps = 21/101 (20%)
Query: 108 CPRGFRGPDCSLPDPCLSSP--CAHGARCSVGPDGRFLCS---------------CPPGY 150
C R RG +C+ P P L + C GA + G LCS CP G+
Sbjct: 289 CFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGF 348
Query: 151 Q--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGY 189
+ SC DVDEC G C+HG C NT G + C CP G+
Sbjct: 349 ERVNGSCE-DVDECATGGRCQHG-ECANTRGGYTCVCPDGF 387
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/77 (38%), Positives = 34/77 (44%), Gaps = 23/77 (29%)
Query: 2 GPGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSR 61
GPG RG RRR P P PV PL+ C NGG C + P R
Sbjct: 129 GPGGRGLLRRRPPQRAPAGKAPVLC-PLI------------------CHNGGVCVK-PDR 168
Query: 62 EAACLCPPGWVGERCQL 78
CLCPP + G+ CQL
Sbjct: 169 ---CLCPPDFAGKFCQL 182
Score = 43.1 bits (100), Expect = 0.003
Identities = 27/67 (40%), Positives = 32/67 (47%), Gaps = 8/67 (11%)
Query: 1179 NGTCVDLVGGFRCTCPPGY----TGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFRC 1232
NG CV + GF C C GY T + C DINEC A CL + G FRC
Sbjct: 1545 NGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCVNARCL-NTDGSFRC 1602
Query: 1233 LCHAGFS 1239
+C GF+
Sbjct: 1603 ICRPGFA 1609
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 13/95 (13%)
Query: 618 EVNIDDCAS-NPCTFGVCRDGINRYDCVCQPGF----TGPLCNVEINEC----ASSPCGE 668
E+ ++C + CT G C + C C G+ T C V+INEC A+SP
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMAC-VDINECDEAEAASPLCV 1589
Query: 669 GGSCVDGENGFRCLCPPGSLP---PLCLPPSHPCA 700
C++ + FRC+C PG P P P+ P A
Sbjct: 1590 NARCLNTDGSFRCICRPGFAPTHQPHHCAPARPRA 1624
Score = 40.8 bits (94), Expect = 0.016
Identities = 57/234 (24%), Positives = 74/234 (31%), Gaps = 65/234 (27%)
Query: 3 PGARGRRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSRE 62
PG GRR P+ + LL L A +AA P S P+
Sbjct: 4 PGTSGRR-------------PLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASV 50
Query: 63 AACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDP 122
A C C PG R + C C R CQ AG R C P P
Sbjct: 51 AVCRCCPGQTSRRSR----CIRAFCRVRS-CQPKKCAGPQR-------------CLNPVP 92
Query: 123 CLSSPCAHGARCSV----------------------GPDGRFLCSCPPGYQGRSCRSDVD 160
+ SP + V GP GR L P + + ++ V
Sbjct: 93 AVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPV- 151
Query: 161 ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE------NPAVPCAPSPCRN 208
C + C +GG C+ RC CP + G C+ P P P R+
Sbjct: 152 LCPL--ICHNGGVCVKPD---RCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRS 200
Score = 36.6 bits (83), Expect = 0.29
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 10/83 (12%)
Query: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPG-----TLGVLCEINEDDCGPGPPLDSGP 1174
E + +EC G C+ + + C C G T +INE D + P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEA----ASP 1586
Query: 1175 RCLHNGTCVDLVGGFRCTCPPGY 1197
C+ N C++ G FRC C PG+
Sbjct: 1587 LCV-NARCLNTDGSFRCICRPGF 1608
Score = 33.1 bits (74), Expect = 3.3
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 3/27 (11%)
Query: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFC 271
C NGG CV C CPP++ G+FC
Sbjct: 157 CHNGGVCV---KPDRCLCPPDFAGKFC 180
Score = 33.1 bits (74), Expect = 3.3
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 1082 EQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCE---DDVDEC----ASQPCQHG 1134
E E + C G C G+ C C GY D D++EC A+ P
Sbjct: 1531 ELEAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVN 1590
Query: 1135 GSCIDLVARYLCSCPPG 1151
C++ + C C PG
Sbjct: 1591 ARCLNTDGSFRCICRPG 1607
Score = 32.3 bits (72), Expect = 5.6
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 3/58 (5%)
Query: 1025 PPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE 1082
P G GR R P R A + V +C GG CV D C+CP G C+
Sbjct: 127 PRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDR---CLCPPDFAGKFCQ 181
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 279 bits (714), Expect = 2e-74
Identities = 251/868 (28%), Positives = 324/868 (37%), Gaps = 243/868 (27%)
Query: 41 PPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP-CAGRGVCQSSVV 98
P C D C +G RC C C PGW G C D H GP C R C++ +
Sbjct: 107 PHCAD--KCVHG-RCIA----PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGAL 159
Query: 99 AGTARFSCRCPRGFRGPDCSLPDPC----LSSPCAHGARCSVGPDGRFL---CSCPPGYQ 151
+C C GFRG C D C + C +C G + C CPPGY
Sbjct: 160 CNPITGACHCAAGFRGWRCE--DRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYT 217
Query: 152 GRSCR------SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP----- 200
G C +C PC++GG C + G C CP+G+ G +C P
Sbjct: 218 GAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGK 275
Query: 201 -CAPS-PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258
C+ C NGGTC + T C C PG+ G+ C+ D+CP V TY
Sbjct: 276 NCSQECQCHNGGTCDAA---TGQCHCSPGYTGERCQ---DECP-------------VGTY 316
Query: 259 NCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318
C + CQ C NGG C++ G +C+C G+ GE C +
Sbjct: 317 GVLC------------AETCQ-----CVNGGKCYHVSG--ACLCEAGFAGERCEARL--- 354
Query: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC- 377
CP G G+ C D C PCH + +P++G C
Sbjct: 355 ---------------------CPEGLYGIKC--DKRC---PCHLENTHSCHPMSGECACK 388
Query: 378 ----------TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR 427
TC PGF G AC Q + C GA+ C + G C C G+ G
Sbjct: 389 PGWSGLYCNETCSPGFYGEAC-QQICSCQNGAD-------CDSVTGK--CTCAPGFKGID 438
Query: 428 CET-------DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS---- 476
C T +N C+N A C G +C C AG+ G C + C S
Sbjct: 439 CSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSI---RCPSGTWGF 493
Query: 477 ------PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDE------CAS-TPCRNGAKCV 523
C+NGG C + ++G +CTC G+ G C+L + CA C + C
Sbjct: 494 GCNLTCQCLNGGAC-NTLDG-TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC- 550
Query: 524 DQPDGYECRCAEGFEGTLCD------------------RNVDDCSPDP--CHHGRCVDGI 563
P CRC G+ G CD +N CSPD C C G
Sbjct: 551 -HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC---ECAPGF 606
Query: 564 ASFSC--ACAPGYTGTRCESQVDEC--RSQPCRHGGKCLDLVDKY---LCR--CPSGTTG 614
+C C+PG+ G RC +C S PC H D + + LC CPSG G
Sbjct: 607 RGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFG 666
Query: 615 VNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVD 674
NC I C +N G C + I+R C C PG+ G C S P
Sbjct: 667 KNC-AGICTCTNN----GTC-NPIDR-SCQCYPGWIGSDC--------SQP--------- 702
Query: 675 GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS-- 732
CPP P C+ H C C +G A G C C PGW+G C+Q
Sbjct: 703 --------CPPAHWGPNCI---HTC---NCHNGAFCSAYDG-ECKCTPGWTGLYCTQRCP 747
Query: 733 ---LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPN--------PCE 781
+D C+ G C D + CTC G GR CE P C
Sbjct: 748 LGFYGKDCALICQCQNGADC--DHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCL 805
Query: 782 HGGRCESAPGQLPVCSCPQGWQGPRCQQ 809
+ C+ G C C GW+G RC Q
Sbjct: 806 NNSTCDHITG---TCYCSPGWKGARCDQ 830
Score = 254 bits (648), Expect = 9e-67
Identities = 245/845 (28%), Positives = 308/845 (36%), Gaps = 207/845 (24%)
Query: 618 EVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGE--GGSCVDG 675
E+ + CA C G C I C C+PG+ G C+S+ G+ G C
Sbjct: 103 EMCVPHCADK-CVHGRC---IAPNTCQCEPGWGG-------TNCSSACDGDHWGPHCTS- 150
Query: 676 ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPG--GFRCV--CEPGWSGPRCSQ 731
RC C G+L C P + G C+ A G G+RC CE G G C Q
Sbjct: 151 ----RCQCKNGAL---CNPIT----------GACHCAAGFRGWRCEDRCEQGTYGNDCHQ 193
Query: 732 SLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSP-------CTPN-PCEHG 783
C+ C+ G TC D + C CPPG G CE L P C PC++G
Sbjct: 194 R-----CQ---CQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNG 243
Query: 784 GRCESAPGQLPVCSCPQGWQGPRCQQDVDE------CAGPAPCGPHGICTNLAGSFSCTC 837
G C G+ CSCP GW G C Q E C+ C G C G C C
Sbjct: 244 GVCHHVTGE---CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHC 298
Query: 838 HGGYTGPSCDQD-------INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRC-ARDVD 889
GYTG C + + + C+NGG C G+ C C GFAG RC AR
Sbjct: 299 SPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCP 356
Query: 890 ECLSN-------PCG-PGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPS---------- 931
E L PC T + H S C C PG+ G +C + CSP
Sbjct: 357 EGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET---CSPGFYGEACQQIC 413
Query: 932 SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLES 991
SC NG C D V C C PG+ G C S PC G G C+
Sbjct: 414 SCQNGADC-DSVTG-KCTCAPGFKGIDC--------STPCPLGTY------GINCS---- 453
Query: 992 FTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRL 1051
SR C+N C C C GW G C IR C G L
Sbjct: 454 -------------SRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR---CPSGTWGFGCNL 497
Query: 1052 EQLCQAGGQCVDEDSSHYCV-----------CPEGRTGSHCEQEVDPCLAQPCQHGGTCR 1100
C GG C D + C C +G G +C + D C H C
Sbjct: 498 TCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD------CSHADGCH 551
Query: 1101 GYMGGYMCECLPGYNGDNCEDDVDECASQP-------CQHGGSCIDLVARYLCSCPPGTL 1153
G C CLPG++G +C+ E P C++G SC +C C PG
Sbjct: 552 PTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFR 607
Query: 1154 GVLCEINEDDCGPG----PPLDSGPRCLHN-GTCVDLVGGFRCTCPPGYTGLRCEADINE 1208
G C+ C PG + P+C+H+ G C + G C C PG+TG C
Sbjct: 608 GTTCQ---RICSPGFYGHRCSQTCPQCVHSSGPCHHITG--LCDCLPGFTGALCNEVCPS 662
Query: 1209 CR-----SGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQP-------CQ 1256
R +G C + C C C+ G+ G C P P C
Sbjct: 663 GRFGKNCAGICTCTNNGTCNPIDRS---CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCH 719
Query: 1257 HG-------GQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
+G G+C+ +PG GL T C F+G C + QC G C
Sbjct: 720 NGAFCSAYDGECKCTPG-WTGLYCTQRCPLGFYGKDCALIC------QCQNGADCDHI-- 770
Query: 1310 GPRCACPPGLSGPSCRSFPGSPPGASNASCAA-APCLHGGSCRPAPLAPFFRCACAQGWT 1368
+C C G G C P G C CL+ +C C C+ GW
Sbjct: 771 SGQCTCRTGFMGRHCEQ--KCPSGTYGYGCRQICDCLNNSTCDHITGT----CYCSPGWK 824
Query: 1369 GPRCE 1373
G RC+
Sbjct: 825 GARCD 829
Score = 248 bits (633), Expect = 5e-65
Identities = 240/800 (30%), Positives = 293/800 (36%), Gaps = 208/800 (26%)
Query: 379 CPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
C PGF +G C V C A+ C H GRC+ CQC G+ G C + +
Sbjct: 94 CCPGFYESGEMC---VPHC---ADKCVH-GRCIAPN---TCQCEPGWGGTNCSSACDGDH 143
Query: 437 SGP-------CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC----------QSSPCV 479
GP C+N A C G C C AGF G CE D C Q C
Sbjct: 144 WGPHCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCE---DRCEQGTYGNDCHQRCQCQ 198
Query: 480 NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAS----------TPCRNGAKCVDQPDGY 529
NG C D V G C CP G++G+ C+ D C PC+NG C
Sbjct: 199 NGATC-DHVTG-ECRCPPGYTGAFCE---DLCPPGKHGPQCEQRCPCQNGGVCHHVTG-- 251
Query: 530 ECRCAEGFEGTLCDRNVDD------CSPD-PCHHGRCVDGIASFSCACAPGYTGTRCESQ 582
EC C G+ GT+C + + CS + CH+G D A+ C C+PGYTG RC+
Sbjct: 252 ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDA-ATGQCHCSPGYTGERCQ-- 308
Query: 583 VDEC----------RSQPCRHGGKCLDLVDKYLCR------------CPSGTTGVNCEV- 619
DEC + C +GGKC + LC CP G G+ C+
Sbjct: 309 -DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKR 367
Query: 620 ------NIDDC--ASNPCTFGVCRDGINRYDC--VCQPGFTGPLCNVEINECASSPCGEG 669
N C S C C+ G + C C PGF G C C+ C G
Sbjct: 368 CPCHLENTHSCHPMSGECA---CKPGWSGLYCNETCSPGFYGEACQ---QICS---CQNG 418
Query: 670 GSCVDGENGFRCLCPPGSLPPLCLPP----------SHPCAHEPCSHGICYDAPGGFRCV 719
C D G +C C PG C P S C + + +C G C
Sbjct: 419 ADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCK--NDAVCSPVDGS--CT 472
Query: 720 CEPGWSGP----RCSQSLARDACE-SQPCRAGGTCSS-DGMGFHCTCPPGVQGRQCELLS 773
C+ GW G RC C + C GG C++ DG CTC PG +G +CEL
Sbjct: 473 CKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT---CTCAPGWRGEKCEL-- 527
Query: 774 PCTPNP----------CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE---------- 813
PC C H C G C C GW G C E
Sbjct: 528 PCQDGTYGLNCAERCDCSHADGCHPTTGH---CRCLPGWSGVHCDSVCAEGRWGPNCSLP 584
Query: 814 --CAGPAPCGPH-GICTNLAGSFSCTCHG----GYTGPSCDQDINDCDPNPCLNGGSCQD 866
C A C P GIC G TC G+ G C Q C + G C
Sbjct: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC----VHSSGPCHH 640
Query: 867 GVGSFSCSCLPGFAGPRCARDVDECLS-----NPCGPGTCTDHVA----SFTCTCPPGYG 917
G C CLPGF G C + C S N G TCT++ +C C PG+
Sbjct: 641 ITGL--CDCLPGFTGALCN---EVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWI 695
Query: 918 GFHCEQDLPDCS-------PSSCFNGGTC--VDGVNSFSCLCRPGYTGAHCQHEA----- 963
G C Q P +C NG C DG C C PG+TG +C
Sbjct: 696 GSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDG----ECKCTPGWTGLYCTQRCPLGFY 751
Query: 964 --DPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT-----LVDWCSRQPCQ--NGGR 1014
D L C +G C H +CTC F G C+ + RQ C N
Sbjct: 752 GKDCALICQCQNGADCD--HISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNST 809
Query: 1015 CVQTGAYCLCPPGWSGRLCD 1034
C C C PGW G CD
Sbjct: 810 CDHITGTCYCSPGWKGARCD 829
Score = 243 bits (619), Expect = 2e-63
Identities = 232/816 (28%), Positives = 302/816 (37%), Gaps = 216/816 (26%)
Query: 457 CMAGF--TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVD----- 509
C GF +G C + C + CV+G +C C G+ G+ C D
Sbjct: 94 CCPGFYESGEMC---VPHC-ADKCVHGRCIAPN----TCQCEPGWGGTNCSSACDGDHWG 145
Query: 510 -ECAST-PCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVD------DCSPD-PCHHGRCV 560
C S C+NGA C P C CA GF G C+ + DC C +G
Sbjct: 146 PHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC 203
Query: 561 DGIASFSCACAPGYTGTRCESQVD------ECRSQ-PCRHGGKCLDLVDKYLCRCPSGTT 613
D + C C PGYTG CE +C + PC++GG C + + C CPSG
Sbjct: 204 DHVTG-ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWM 260
Query: 614 GVNCEVNIDDCASNPCTFGVCRDGIN-RYDCVCQPGFTGPLCNVEINECASSPCGEGGSC 672
G C PC G R G N +C C G T C+ +C SP G C
Sbjct: 261 GTVC--------GQPCPEG--RFGKNCSQECQCHNGGT---CDAATGQCHCSPGYTGERC 307
Query: 673 VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS 732
D CP G+ LC + C + + G CY G C+CE G++G RC
Sbjct: 308 QDE-------CPVGTYGVLC---AETC--QCVNGGKCYHVSGA--CLCEAGFAGERCEAR 353
Query: 733 LARDA-----CESQ-PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPN-------- 778
L + C+ + PC T S M C C PG G C C+P
Sbjct: 354 LCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCN--ETCSPGFYGEACQQ 411
Query: 779 --PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGI-CTNLAG---- 831
C++G C+S G+ C+C G++G +C+ P P G +GI C++ G
Sbjct: 412 ICSCQNGADCDSVTGK---CTCAPGFKGI-------DCSTPCPLGTYGINCSSRCGCKND 461
Query: 832 ------SFSCTCHGGYTGPSCDQDIND------CDPN-PCLNGGSCQDGVGSFSCSCLPG 878
SCTC G+ G C C+ CLNGG+C G+ C+C PG
Sbjct: 462 AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPG 519
Query: 879 FAGPRCARDVDECLSNPCGPGT----CTD----------HVASFTCTCPPGYGGFHCEQD 924
+ G +C PC GT C + H + C C PG+ G HC+
Sbjct: 520 WRGEKCEL--------PCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSV 571
Query: 925 L------PDCS-PSSCFNGGTC---------VDGVNSFSC--LCRPGYTGAHCQHEADPC 966
P+CS P C NG +C G +C +C PG+ G C C
Sbjct: 572 CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC 631
Query: 967 L--SRPCLH------------GGVCSAAHPGFR--------CTCLESFT----GPQCQTL 1000
+ S PC H G +C+ P R CTC + T CQ
Sbjct: 632 VHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCY 691
Query: 1001 VDW----CSRQPC---------------QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCR 1041
W CS QPC NG C C C PGW+G C R C
Sbjct: 692 PGWIGSDCS-QPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQR---CP 747
Query: 1042 EAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRG 1101
L CQ G C + S C C G G HCEQ+ C G G
Sbjct: 748 LGFYGKDCALICQCQNGADC--DHISGQCTCRTGFMGRHCEQK--------CPSG--TYG 795
Query: 1102 YMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSC 1137
Y +C+CL N C+ C P G C
Sbjct: 796 YGCRQICDCL---NNSTCDHITGTCYCSPGWKGARC 828
Score = 207 bits (527), Expect = 1e-52
Identities = 197/704 (27%), Positives = 240/704 (34%), Gaps = 219/704 (31%)
Query: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPC----HSGPCAGRGV 92
G C C NG C + C CPPG+ G C ED C H C R
Sbjct: 185 GTYGNDCHQRCQCQNGATCDHVTGE---CRCPPGYTGAFC--EDLCPPGKHGPQCEQRCP 239
Query: 93 CQSSVVAGTARFSCRCPRGFRGPDCSLPDP--------CLSSPCAHGARCSVGPDGRFLC 144
CQ+ V C CP G+ G C P P C +G C C
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG---QC 296
Query: 145 SCPPGYQGRSCRSDVDECRVGE---------PCRHGGTCLNTPGSFRCQCPAGYTGPLCE 195
C PGY G C+ DEC VG C +GG C + G+ C C AG+ G CE
Sbjct: 297 HCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCE 351
Query: 196 NPAVP----------------------------CAPSP---------------------- 205
P CA P
Sbjct: 352 ARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQ 411
Query: 206 ---CRNGGTCRQSGDLTYDCACLPGFEGQNCE---------VNVDDCPGHRCLNGGTC-- 251
C+NG C +T C C PGF+G +C +N G C N C
Sbjct: 412 ICSCQNGADC---DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCG--CKNDAVCSP 466
Query: 252 VDGVNTYNCQCPPEWTGQFCTEDVDE------CQLQPNACHNGGTCFNTLGGHSCVCVNG 305
VDG +C C W G C+ C L C NGG C NTL G +C C G
Sbjct: 467 VDG----SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ-CLNGGAC-NTLDG-TCTCAPG 519
Query: 306 WTGESCSQNIDD------CATAV-CFHGATCHDRVASFYCACPMGKTGLLCHLDDACV-- 356
W GE C D CA C H CH +C C G +G+ H D C
Sbjct: 520 WRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGV--HCDSVCAEG 575
Query: 357 ------SNPCH---------EDAICDTNPVNGRAIC--TCPPGFTGGACDQDVDECSIGA 399
S PC+ +D IC+ P C C PGF G C Q +C +
Sbjct: 576 RWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
Query: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG----------PCRNQATC--L 447
PC H+ + LC C G+TG C C SG C N TC +
Sbjct: 636 GPCHHI--------TGLCDCLPGFTGALCN---EVCPSGRFGKNCAGICTCTNNGTCNPI 684
Query: 448 DRIGQFTCICMAGFTGTYCEVDIDECQSSP-------CVNGGVCKDRVNGFSCT------ 494
DR +C C G+ G+ C P C NG C CT
Sbjct: 685 DR----SCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGL 740
Query: 495 -----CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCD------ 543
CP GF G C L C+NGA C D G +C C GF G C+
Sbjct: 741 YCTQRCPLGFYGKDCAL------ICQCQNGADC-DHISG-QCTCRTGFMGRHCEQKCPSG 792
Query: 544 ------RNVDDC-SPDPCHHGRCVDGIASFSCACAPGYTGTRCE 580
R + DC + C H + +C C+PG+ G RC+
Sbjct: 793 TYGYGCRQICDCLNNSTCDH-------ITGTCYCSPGWKGARCD 829
Score = 199 bits (507), Expect = 2e-50
Identities = 199/734 (27%), Positives = 252/734 (34%), Gaps = 226/734 (30%)
Query: 875 CLPGF--AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL------P 926
C PGF +G C V C ++ C G C +A TC C PG+GG +C P
Sbjct: 94 CCPGFYESGEMC---VPHC-ADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGP 146
Query: 927 DC-SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADP------CLSR-PCLHGGVCS 978
C S C NG C + +C C G+ G C+ + C R C +G C
Sbjct: 147 HCTSRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCD 204
Query: 979 AAHPGFRCTCLESFTGPQCQTLVD------WCSRQ-PCQNGGRCVQTGAYCLCPPGWSGR 1031
H C C +TG C+ L C ++ PCQNGG C C CP GW G
Sbjct: 205 --HVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGT 262
Query: 1032 LCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQ 1091
+C PC PEGR G +C QE
Sbjct: 263 VC---GQPC--------------------------------PEGRFGKNCSQECQ----- 282
Query: 1092 PCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG 1151
C +GGTC G C C PGY G+ C+D+ CP G
Sbjct: 283 -CHNGGTCDAATG--QCHCSPGYTGERCQDE-------------------------CPVG 314
Query: 1152 TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS 1211
T GVLC + C +C++ G C + G C C G+ G RCEA + C
Sbjct: 315 TYGVLC---AETC----------QCVNGGKCYHVSGA--CLCEAGFAGERCEARL--CPE 357
Query: 1212 G----------ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP------CES-QP 1254
G CH +T C G C C G+SG C SP C+
Sbjct: 358 GLYGIKCDKRCPCHLENTHSCHPMSG---ECACKPGWSGLYCNETCSPGFYGEACQQICS 414
Query: 1255 CQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPV---GVPCQQ----- 1306
CQ+G C +T C CA F G C CP+ G+ C
Sbjct: 415 CQNGADC-------DSVTGKCTCAPGFKGIDC--------STPCPLGTYGINCSSRCGCK 459
Query: 1307 -----TPRGPRCACPPGLSGPSCRSFPGSPPGASNASC-AAAPCLHGGSCRPAPLAPFFR 1360
+P C C G G C P G C CL+GG+C
Sbjct: 460 NDAVCSPVDGSCTCKAGWHGVDCSI--RCPSGTWGFGCNLTCQCLNGGACNTLD----GT 513
Query: 1361 CACAQGWTGPRCEAPAA----APEVSEEPRCPRA-ACQAKRGDQR---------CDREC- 1405
C CA GW G +CE P +E C A C G R CD C
Sbjct: 514 CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCA 573
Query: 1406 ---------------NSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPA 1450
N C D G C + G C+ + C F RC C P
Sbjct: 574 EGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRI-CSPGFYGHRCSQTC--PQ 630
Query: 1451 CLYDNFDCH---------AGGRERTCNPV-----YEKYCADHFA---DGRCDQGCNTEEC 1493
C++ + CH G CN V + K CA +G C+ + +C
Sbjct: 631 CVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQC 690
Query: 1494 --GWDGLDCASEVP 1505
GW G DC+ P
Sbjct: 691 YPGWIGSDCSQPCP 704
Score = 120 bits (302), Expect = 1e-26
Identities = 123/450 (27%), Positives = 167/450 (37%), Gaps = 106/450 (23%)
Query: 1109 ECLPGY--NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGP 1166
+C PG+ +G+ C V CA + C HG CI A C C PG G C D
Sbjct: 93 QCCPGFYESGEMC---VPHCADK-CVHG-RCI---APNTCQCEPGWGGTNCSSACDGDHW 144
Query: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGA--------CHAAH 1218
GP S +C + C + G C C G+ G RCE + C G C +
Sbjct: 145 GPHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCE---DRCEQGTYGNDCHQRCQCQN 199
Query: 1219 TRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP------CESQ-PCQHGGQCRPSPGPGGGL 1271
C G C C G++G C+ + P CE + PCQ+GG C G
Sbjct: 200 GATCDHVTG---ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE---- 252
Query: 1272 TFTCHCAQPFWGPRCE------RVARSC-RELQCPVGVPCQQTPRGPRCACPPGLSGPSC 1324
C C + G C R ++C +E QC G C +C C PG +G C
Sbjct: 253 ---CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERC 307
Query: 1325 RSFPGSPPGASNASCA-AAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEA---PAAAPE 1380
+ P G CA C++GG C A C C G+ G RCEA P
Sbjct: 308 QD--ECPVGTYGVLCAETCQCVNGGKCYHVSGA----CLCEAGFAGERCEARLCPEGLYG 361
Query: 1381 VSEEPRCP-----RAACQAKRGDQRCDRECNSPGCGWDGGDCS--LSVGDPWRQCEAL-- 1431
+ + RCP +C G+ C GW G C+ S G C+ +
Sbjct: 362 IKCDKRCPCHLENTHSCHPMSGECACKP-------GWSGLYCNETCSPGFYGEACQQICS 414
Query: 1432 -----QCWRLFNNSRCDPA-----CSSPACLYDNFDCHAGGR-----ERTCNPVYEKYCA 1476
C + C P CS+P C + + R + C+PV
Sbjct: 415 CQNGADCDSVTGKCTCAPGFKGIDCSTP-CPLGTYGINCSSRCGCKNDAVCSPV------ 467
Query: 1477 DHFADGRCDQGCNTEECGWDGLDCASEVPA 1506
DG C T + GW G+DC+ P+
Sbjct: 468 ----DGSC-----TCKAGWHGVDCSIRCPS 488
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 279 bits (713), Expect = 3e-74
Identities = 255/876 (29%), Positives = 311/876 (35%), Gaps = 241/876 (27%)
Query: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
CP + D +P + C HG RC V PD C C PG+ G C S D G
Sbjct: 89 CPGYYESGDFCIP--LCTEECVHG-RC-VSPD---TCHCEPGWGGPDCSSGCDSDHWGPH 141
Query: 168 CRHGGTCLN----TPGSFRCQCPAGYTGPLCENPAVP------C-APSPCRNGGTCRQSG 216
C + C N P + C C AG+ G CE P C P CR+G +C
Sbjct: 142 CSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA 201
Query: 217 DLTYDCACLPGFEGQNCEVNVDDCP--GH--------RCLNGGTCVDGVNTYNCQCPPEW 266
+C C PG+ G CE + CP H C NGGTC T C CPP W
Sbjct: 202 G---ECLCAPGYTGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHH--ITGECACPPGW 253
Query: 267 TGQFCTEDVDECQLQPNA-----CHNGGTCFNTLGGHSCVCVNGWTGESCSQNID----- 316
TG C + N CH+GG C + G C C G+ G+ C +
Sbjct: 254 TGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFG 311
Query: 317 -DCAT-AVCFHGATCHDRVASFYCACPMGKTGLLC---------HLDDACVSNPCHEDAI 365
C+ C +G C + C C G G C H + PC D
Sbjct: 312 FQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNT 369
Query: 366 CDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTG 425
+PV G CTC PG++G C++ C GY G
Sbjct: 370 ISCHPVTG--ACTCQPGWSGHHCNE---------------------------SCPVGYYG 400
Query: 426 PRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDI------DECQS-SPC 478
C+ L C+N A C G C C GF G C V C S C
Sbjct: 401 DGCQ------LPCTCQNGADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSC 452
Query: 479 VNGGVCKDRVNGFSCTCPSGFSGSTCQLDVD------EC-ASTPCRNGAKCVDQPDGYEC 531
NGG C V+G SCTC G+ G C L C S C NGA C P C
Sbjct: 453 NNGGTCSP-VDG-SCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC--SPIDGSC 508
Query: 532 RCAEGFEGTLCDRNVDD------CSPD-PCHHGRCVDGIASFSCACAPGYTGTRCESQVD 584
C G+ G C+ D CS C H D + C C G+TG RC+S
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG-HCCCLAGWTGIRCDS--- 564
Query: 585 ECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCV 644
CP G G NC V+ C+ DG C
Sbjct: 565 ----------------------TCPPGRWGPNCSVSCSCENGGSCS---PEDG----SCE 595
Query: 645 CQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH--E 702
C PGF GPLC + +CPPG C P C H
Sbjct: 596 CAPGFRGPLC-------------------------QRICPPGFYGHGCAQPCPLCVHSSR 630
Query: 703 PCSH--GICYDAPGGFRCVCEPGWSGPRCSQSLA-----RDACESQPCRAGGTCSS-DGM 754
PC H GI C C PG+SG C+Q A +D + C GTCS DG
Sbjct: 631 PCHHISGI---------CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG- 680
Query: 755 GFHCTCPPGVQGRQCELLSPCTPN----------PCEHGGRCESAPGQLPVCSCPQGWQG 804
C C PG G+ C C P C +G C + G C C GW G
Sbjct: 681 --SCQCFPGWIGKDCS--QACPPGFWGPACFHACSCHNGASCSAEDG---ACHCTPGWTG 733
Query: 805 PRCQQDV------DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN-- 856
C Q +C C C +++G CTC G+TG C+Q C P
Sbjct: 734 LFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQ---RCAPGTF 788
Query: 857 --------PCLNGGSCQDGVGSFSCSCLPGFAGPRC 884
C+N +C G +C C PGF G RC
Sbjct: 789 GYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRC 822
Score = 267 bits (683), Expect = 8e-71
Identities = 252/831 (30%), Positives = 326/831 (39%), Gaps = 190/831 (22%)
Query: 570 CAPGY--TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
C PGY +G C + C ++ C HG +C V C C G G +C D
Sbjct: 88 CCPGYYESGDFC---IPLC-TEECVHG-RC---VSPDTCHCEPGWGGPDCSSGCDSDHWG 139
Query: 628 P-CTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRC--LCP 684
P C+ NR C CQ G LCN C C G G+RC LC
Sbjct: 140 PHCS--------NR--CQCQ---NGALCNPITGACV---------CAAGFRGWRCEELCA 177
Query: 685 PGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA----CES 740
PG+ C P C HG D G C+C PG++G C + + CE
Sbjct: 178 PGTHGKGCQLPCQ------CRHGASCDPRAG-ECLCAPGYTGVYCEELCPPGSHGAHCEL 230
Query: 741 Q-PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPN----------PCEHGGRCESA 789
+ PC+ GGTC + C CPPG G C PC P PC HGG+C+
Sbjct: 231 RCPCQNGGTCHH--ITGECACPPGWTGAVCA--QPCPPGTFGQNCSQDCPCHHGGQCDHV 286
Query: 790 PGQLPVCSCPQGWQGPRCQQDVD------ECAGPAPCGPHGICTNLAGSFSCTCHGGYTG 843
GQ C C G+ G RCQ++ +C+ C G C+ G+ C C GY G
Sbjct: 287 TGQ---CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKG 341
Query: 844 PSCDQDI-------NDCD-PNPCL--NGGSCQDGVGSFSCSCLPGFAGPRCARDV----- 888
P C + + C P PC N SC G+ C+C PG++G C
Sbjct: 342 PRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYY 399
Query: 889 -DECLSNPCGPGTCTD----HVASFTCTCPPGYGGFHCEQDL------PDCSP-SSCFNG 936
D C PC TC + H + CTC PG+ G C P+CS SC NG
Sbjct: 400 GDGC-QLPC---TCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNG 455
Query: 937 GTC--VDGVNSFSCLCRPGYTGAHCQHEADPCLSRP----------CLHGGVCSAAHPGF 984
GTC VDG SC C+ G+ G C PC S C +G CS
Sbjct: 456 GTCSPVDG----SCTCKEGWQGLDCTL---PCPSGTWGLNCNESCTCANGAACSPIDGS- 507
Query: 985 RCTCLESFTGPQCQ------TLVDWCSRQ-PCQNGGRCVQTGAYCLCPPGWSGRLCDIRS 1037
C+C + G C+ T CS C + C +C C GW+G CD
Sbjct: 508 -CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTC 566
Query: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYC-----------VCPEGRTGSHCEQEVD 1086
P R + C+ GG C ED S C +CP G G C Q
Sbjct: 567 PPGRWGP---NCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 623
Query: 1087 PCL--AQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV------DECASQ-PCQHGGSC 1137
C+ ++PC H + G +CECLPG++G C +CA C + G+C
Sbjct: 624 LCVHSSRPCHH-------ISG-ICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTC 675
Query: 1138 IDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLH-----NGTCVDLVGGFRCT 1192
+ C C PG +G C C PG GP C H NG G C
Sbjct: 676 SPIDGS--CQCFPGWIGKDCS---QACPPG---FWGPACFHACSCHNGASCSAEDG-ACH 726
Query: 1193 CPPGYTGL----RCEADI--NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTV 1246
C PG+TGL RC A +C C + C G +C C GF+G C+
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDC-GRVCQCQNGASCDHISG---KCTCRTGFTGQHCEQR 782
Query: 1247 LSPCE-SQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCREL 1296
+P CQ +C + +T TC+C+ F G RC++ A EL
Sbjct: 783 CAPGTFGYGCQQLCECMNN-STCDHVTGTCYCSPGFKGIRCDQAALMMEEL 832
Score = 266 bits (680), Expect = 2e-70
Identities = 249/856 (29%), Positives = 312/856 (36%), Gaps = 229/856 (26%)
Query: 457 CMAGF--TGTYC-EVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDE--- 510
C G+ +G +C + +EC CV+ C C G+ G C D
Sbjct: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCH---------CEPGWGGPDCSSGCDSDHW 138
Query: 511 ---CAST-PCRNGAKCVDQPDGYECRCAEGFEGTLCDR------NVDDCS-PDPCHHGRC 559
C++ C+NGA C P C CA GF G C+ + C P C HG
Sbjct: 139 GPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS 196
Query: 560 VDGIASFSCACAPGYTGTRCE------SQVDECRSQ-PCRHGGKCLDLVDKYLCRCPSGT 612
D A C CAPGYTG CE S C + PC++GG C + + C CP G
Sbjct: 197 CDPRAG-ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGE--CACPPGW 253
Query: 613 TGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC 672
TG C + PC G ++ DC C G C+ +C C
Sbjct: 254 TGAVC--------AQPCPPGTFGQNCSQ-DCPCHHGGQ---CDHVTGQC---------HC 292
Query: 673 VDGENGFRCL--CPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRC 729
G G RC CP GS C H C +G C G C CEPG+ GPRC
Sbjct: 293 TAGYMGDRCQEECPFGSFGFQC------SQHCDCHNGGQCSPTTGA--CECEPGYKGPRC 344
Query: 730 SQSLARDACESQ------PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC-------- 775
+ L + PC A T S + CTC PG G C P
Sbjct: 345 QERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ 404
Query: 776 TPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV------DECAGPAPCGPHGICTNL 829
P C++G C S G C+C G+ G C C+ C G C+ +
Sbjct: 405 LPCTCQNGADCHSITGG---CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPV 461
Query: 830 AGSFSCTCHGGYTG-------PSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGP 882
G SCTC G+ G PS +N + C NG +C G SCSC PG+ G
Sbjct: 462 DG--SCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG--SCSCTPGWLGD 517
Query: 883 RCARDVDECLSNPCGPGT----CTDHV----------ASFTCTCPPGYGGFHCEQDL--- 925
C PC GT C++H + C C G+ G C+
Sbjct: 518 TC--------ELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPG 569
Query: 926 ---PDCSPS-SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE----------ADPC----- 966
P+CS S SC NGG+C SC C PG+ G CQ A PC
Sbjct: 570 RWGPNCSVSCSCENGGSC--SPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVH 627
Query: 967 LSRPCLH-GGVCSAAHPGF-----RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA 1020
SRPC H G+C PGF C + G C L CS C N G C
Sbjct: 628 SSRPCHHISGICECL-PGFSGALCNQVCAGGYFGQDCAQL---CS---CANNGTCSPIDG 680
Query: 1021 YCLCPPGWSGRLCDIRSLP------CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPE 1074
C C PGW G+ C P C A + C G C ED + C C
Sbjct: 681 SCQCFPGWIGKDCSQACPPGFWGPACFHACS---------CHNGASCSAEDGA--CHCTP 729
Query: 1075 GRTGSHCEQEV-------DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECA 1127
G TG C Q D CQ+G +C G C C G+ G +CE
Sbjct: 730 GWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQ------ 781
Query: 1128 SQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVG 1187
C PGT G C + C C++N TC + G
Sbjct: 782 -------------------RCAPGTFGYGC---QQLC----------ECMNNSTCDHVTG 809
Query: 1188 GFRCTCPPGYTGLRCE 1203
C C PG+ G+RC+
Sbjct: 810 --TCYCSPGFKGIRCD 823
Score = 261 bits (666), Expect = 7e-69
Identities = 242/850 (28%), Positives = 308/850 (36%), Gaps = 228/850 (26%)
Query: 53 GRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP-CAGRGVCQSSVVAGTARFSCRCPR 110
GRC + C C PGW G C D H GP C+ R CQ+ + +C C
Sbjct: 110 GRCVSPDT----CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAA 165
Query: 111 GFRGPDCSLPDPC----------LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR---- 156
GFRG C + C L C HGA C C C PGY G C
Sbjct: 166 GFRGWRCE--ELCAPGTHGKGCQLPCQCRHGASCDPRAGE---CLCAPGYTGVYCEELCP 220
Query: 157 --SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP------CAPS-PCR 207
S C + PC++GGTC + G C CP G+TG +C P P C+ PC
Sbjct: 221 PGSHGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCH 278
Query: 208 NGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP----GHRCL------NGGTCVDGVNT 257
+GG C +T C C G+ G C+ ++CP G +C NGG C T
Sbjct: 279 HGGQC---DHVTGQCHCTAGYMGDRCQ---EECPFGSFGFQCSQHCDCHNGGQC--SPTT 330
Query: 258 YNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCF-------NTLGGH----SCVCVNGW 306
C+C P + G C E +L P H G NT+ H +C C GW
Sbjct: 331 GACECEPGYKGPRCQE-----RLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGW 385
Query: 307 TGESCSQNI------DDC-ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNP 359
+G C+++ D C C +GA CH C C G G +C + A +
Sbjct: 386 SGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYG 443
Query: 360 CHEDAICDTN------PVNGRAICTCPPGFTGGACDQDVDECSIGAN-----PCEHLGRC 408
+ +IC N PV+G CTC G+ G C + G N C + C
Sbjct: 444 PNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC 501
Query: 409 VNTQGSFLCQCGRGYTGPRCETDVNECLSG-PCRNQATCLDRIG----QFTCICMAGFTG 463
GS C C G+ G CE + G C C G C C+AG+TG
Sbjct: 502 SPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTG 559
Query: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCV 523
C+ TCP G G C + S C NG C
Sbjct: 560 IRCD-------------------------STCPPGRWGPNCSV------SCSCENGGSC- 587
Query: 524 DQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQV 583
P+ C CA GF G LC R C PG+ G C
Sbjct: 588 -SPEDGSCECAPGFRGPLCQR------------------------ICPPGFYGHGCAQPC 622
Query: 584 DEC--RSQPCRHGG---KCLDLVDKYLCR--CPSGTTGVNCEVNIDDCASNPCTFGVCR- 635
C S+PC H +CL LC C G G +C + CA+N G C
Sbjct: 623 PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC-AQLCSCANN----GTCSP 677
Query: 636 -DGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP 694
DG C C PG+ G C S C PPG P C
Sbjct: 678 IDG----SCQCFPGWIGKDC--------SQAC-----------------PPGFWGPACF- 707
Query: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS-----LARDACESQPCRAGGTC 749
H C+ C +G A G C C PGW+G C+Q +D C+ G +C
Sbjct: 708 --HACS---CHNGASCSAEDG-ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC 761
Query: 750 SSDGMGFHCTCPPGVQGRQCELLSPCTPN----------PCEHGGRCESAPGQLPVCSCP 799
D + CTC G G+ CE C P C + C+ G C C
Sbjct: 762 --DHISGKCTCRTGFTGQHCE--QRCAPGTFGYGCQQLCECMNNSTCDHVTG---TCYCS 814
Query: 800 QGWQGPRCQQ 809
G++G RC Q
Sbjct: 815 PGFKGIRCDQ 824
Score = 240 bits (612), Expect = 1e-62
Identities = 236/817 (28%), Positives = 296/817 (36%), Gaps = 226/817 (27%)
Query: 379 CPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
C PG+ +G C + C+ C H GRCV+ C C G+ GP C + +
Sbjct: 88 CCPGYYESGDFC---IPLCT---EECVH-GRCVSPD---TCHCEPGWGGPDCSSGCDSDH 137
Query: 437 SGP-------CRNQATCLDRIGQFTCICMAGFTGTYCE------VDIDECQ-SSPCVNGG 482
GP C+N A C G C+C AGF G CE CQ C +G
Sbjct: 138 WGPHCSNRCQCQNGALCNPITG--ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGA 195
Query: 483 VCKDRVNGFSCT-----------CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYEC 531
C R C CP G G+ C+L PC+NG C EC
Sbjct: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL------RCPCQNGGTCHHITG--EC 247
Query: 532 RCAEGFEGTLCDRNV------DDCSPD-PCHHGRCVDGIASFSCACAPGYTGTRCESQVD 584
C G+ G +C + +CS D PCHHG D + C C GY G RC+ +
Sbjct: 248 ACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG-QCHCTAGYMGDRCQEECP 306
Query: 585 ------ECRSQ-PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG 637
+C C +GG+C C C G G C+ + C +G
Sbjct: 307 FGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERL------------CPEG 352
Query: 638 INRYDCVCQPGFTGPL-CNVEINECASSPCGEGGSCVDGENGFRC--LCPPGSLPPLCLP 694
++ PG T P C+ + N + P +C G +G C CP G C
Sbjct: 353 LHG------PGCTLPCPCDAD-NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC-- 403
Query: 695 PSHPCAHEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSLARDA----CESQ-PCRAGGT 748
PC C +G C+ GG C C PG+ G C+ S A C S C GGT
Sbjct: 404 -QLPCT---CQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT 457
Query: 749 CSS-DGMGFHCTCPPGVQGRQCELLSP-----------CTPNPCEHGGRCESAPGQLPVC 796
CS DG CTC G QG C L P CT C +G C G C
Sbjct: 458 CSPVDGS---CTCKEGWQGLDCTLPCPSGTWGLNCNESCT---CANGAACSPIDGS---C 508
Query: 797 SCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAG----SFSCTCHGGYTGPSCDQDIND 852
SC GW G C+ + C H C++ G + C C G+TG CD +
Sbjct: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD---ST 565
Query: 853 CDPN----------PCLNGGSCQDGVGSFSCS-----------CLPGFAGPRCARDVDEC 891
C P C NGGSC GS C+ C PGF G CA+ C
Sbjct: 566 CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLC 625
Query: 892 L--SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP------DCSP-SSCFNGGTC--V 940
+ S PC H S C C PG+ G C Q DC+ SC N GTC +
Sbjct: 626 VHSSRPC-------HHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPI 678
Query: 941 DGVNSFSCLCRPGYTGAHCQHEADPCLSRP-------CLHGGVCSAAH------PGF--- 984
DG SC C PG+ G C P P C +G CSA PG+
Sbjct: 679 DG----SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGL 734
Query: 985 --------------------------------RCTCLESFTGPQCQ------TLVDWCSR 1006
+CTC FTG C+ T C +
Sbjct: 735 FCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ 794
Query: 1007 Q-PCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCRE 1042
C N C C C PG+ G CD +L E
Sbjct: 795 LCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEE 831
Score = 229 bits (585), Expect = 2e-59
Identities = 229/826 (27%), Positives = 286/826 (34%), Gaps = 212/826 (25%)
Query: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDE------ 813
C PG + CT C HG RC S C C GW GP C D
Sbjct: 88 CCPGYYESGDFCIPLCTEE-CVHG-RCVSPD----TCHCEPGWGGPDCSSGCDSDHWGPH 141
Query: 814 CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDI------NDCD-PNPCLNGGSCQD 866
C+ C +C + G+ C C G+ G C++ C P C +G SC
Sbjct: 142 CSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
Query: 867 GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP 926
G C C PG+ G C CPPG G HCE P
Sbjct: 200 RAGE--CLCAPGYTGVYCEE------------------------LCPPGSHGAHCELRCP 233
Query: 927 DCSPSSCFNGGTC--VDGVNSFSCLCRPGYTGAHCQHEADP-------CLSRPCLHGGVC 977
C NGGTC + G C C PG+TGA C P PC HGG C
Sbjct: 234 ------CQNGGTCHHITG----ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC 283
Query: 978 SAAHPGFRCTCLESFTGPQCQTLVDW------CSRQ-PCQNGGRCVQTGAYCLCPPGWSG 1030
H +C C + G +CQ + CS+ C NGG+C T C C PG+ G
Sbjct: 284 D--HVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKG 341
Query: 1031 RLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV----- 1085
C R C E G L C A + C C G +G HC +
Sbjct: 342 PRCQERL--CPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYY 399
Query: 1086 -DPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV------DECASQ-PCQHGGS 1136
D C L CQ+G C GG C C PG+ G+ C C+S C +GG+
Sbjct: 400 GDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT 457
Query: 1137 CIDLVARYLC-----------------------------------------SCPPGTLGV 1155
C + C SC PG LG
Sbjct: 458 CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGD 517
Query: 1156 LCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSG--- 1212
CE+ D G C H C + G C C G+TG+RC++ R G
Sbjct: 518 TCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCDSTCPPGRWGPNC 575
Query: 1213 --ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL----------SPC-----ESQPC 1255
+C + C + G C C GF GP CQ + PC S+PC
Sbjct: 576 SVSCSCENGGSCSPEDGS---CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPC 632
Query: 1256 QH-GGQCRPSPGPGGGLTFTCH--CAQPFWGPRCERVARSCRELQC-PVGVPCQQTPR-- 1309
H G C PG G L C+ CA ++G C ++ C P+ CQ P
Sbjct: 633 HHISGICECLPGFSGAL---CNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWI 689
Query: 1310 GPRC--ACPPGLSGPSC----RSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFF---- 1359
G C ACPPG GP+C G+ A + +C P G C A FF
Sbjct: 690 GKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDC 749
Query: 1360 -----------------RCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCD 1402
+C C G+TG CE A P CQ Q C
Sbjct: 750 GRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCA-------PGTFGYGCQ-----QLC- 796
Query: 1403 REC-NSPGCGWDGGDCSLSVGDPWRQCE--ALQCWRLFNNSRCDPA 1445
EC N+ C G C S G +C+ AL L ++ PA
Sbjct: 797 -ECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISPA 841
Score = 213 bits (542), Expect = 2e-54
Identities = 205/706 (29%), Positives = 251/706 (35%), Gaps = 183/706 (25%)
Query: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVG-------------ERCQLE 79
L PG+ C PC NGG C + C CPPGW G + C +
Sbjct: 218 LCPPGSHGAHCELRCPCQNGGTCHHITGE---CACPPGWTGAVCAQPCPPGTFGQNCSQD 274
Query: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCR--CPRGFRGPDCSLPDPCLSSPCAHGARCSVG 137
PCH G Q AG C+ CP G G CS C +G +CS
Sbjct: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQ-----HCDCHNGGQCSPT 329
Query: 138 PDGRFLCSCPPGYQGRSCRSDV-------DECRVGEPCRHGGT--CLNTPGSFRCQ---- 184
C C PGY+G C+ + C + PC T C G+ CQ
Sbjct: 330 TGA---CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWS 386
Query: 185 -------CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV 237
CP GY G C+ +PC C+NG C +T C C PGF G+ C V+
Sbjct: 387 GHHCNESCPVGYYGDGCQ---LPCT---CQNGADCHS---ITGGCTCAPGFMGEVCAVSC 437
Query: 238 ------DDCPGH-RCLNGGTC--VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNA---- 284
+C C NGGTC VDG +C C W G CT N
Sbjct: 438 AAGTYGPNCSSICSCNNGGTCSPVDG----SCTCKEGWQGLDCTLPCPSGTWGLNCNESC 493
Query: 285 -CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV-------CFHGATCHDRVASF 336
C NG C G SC C GW G++C D + C H C D V
Sbjct: 494 TCANGAACSPIDG--SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGC-DPVTG- 549
Query: 337 YCACPMGKTGLLCHLDDAC----------VSNPCH-------EDAICDTNPVNGRAICT- 378
+C C G TG+ C D C VS C ED C+ P +C
Sbjct: 550 HCCCLAGWTGIRC--DSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQR 607
Query: 379 -CPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS 437
CPPGF G C Q C + PC H+ S +C+C G++G C
Sbjct: 608 ICPPGFYGHGCAQPCPLCVHSSRPCHHI--------SGICECLPGFSGALC--------- 650
Query: 438 GPCRNQATCLDRIGQFTC-ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCP 496
NQ GQ +C GT +D CQ C G + KD S CP
Sbjct: 651 ----NQVCAGGYFGQDCAQLCSCANNGTCSPID-GSCQ---CFPGWIGKD----CSQACP 698
Query: 497 SGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV------DDCS 550
GF G C C+ C NGA C DG C C G+ G C + DC
Sbjct: 699 PGFWGPAC---FHACS---CHNGASC-SAEDG-ACHCTPGWTGLFCTQRCPAAFFGKDCG 750
Query: 551 -PDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 609
C +G D I S C C G+TG CE RC
Sbjct: 751 RVCQCQNGASCDHI-SGKCTCRTGFTGQHCEQ-------------------------RCA 784
Query: 610 SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCN 655
GT G C+ + +C +N V C C PGF G C+
Sbjct: 785 PGTFGYGCQ-QLCECMNNSTCDHVTG------TCYCSPGFKGIRCD 823
Score = 204 bits (518), Expect = 1e-51
Identities = 195/715 (27%), Positives = 238/715 (33%), Gaps = 188/715 (26%)
Query: 875 CLPG------FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL--- 925
C PG F P C +EC+ C V+ TC C PG+GG C
Sbjct: 88 CCPGYYESGDFCIPLCT---EECVHGRC--------VSPDTCHCEPGWGGPDCSSGCDSD 136
Query: 926 ---PDCSPS-SCFNGG---------TCVDGVNSFSC--LCRPGYTGAHCQHEADPCLSRP 970
P CS C NG C G + C LC PG G CQ PC
Sbjct: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQL---PC---Q 190
Query: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCS-------RQPCQNGGRCVQTGAYCL 1023
C HG C C C +TG C+ L S R PCQNGG C C
Sbjct: 191 CRHGASCDPR--AGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECA 248
Query: 1024 CPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV-----------C 1072
CPPGW+G +C + PC + C GGQC +C C
Sbjct: 249 CPPGWTGAVC---AQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEEC 305
Query: 1073 PEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV-------DE 1125
P G G C Q D C +GG C G CEC PGY G C++ +
Sbjct: 306 PFGSFGFQCSQHCD------CHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPG 357
Query: 1126 CASQ-PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC-----GPGPPLDSGPRCLHN 1179
C PC + C+C PG G C + C G G L C +
Sbjct: 358 CTLPCPCDADNTISCHPVTGACTCQPGWSGHHC---NESCPVGYYGDGCQLPC--TCQNG 412
Query: 1180 GTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239
C + GG CTC PG+ G C C AG
Sbjct: 413 ADCHSITGG--CTCAPGFMGEVCAVS----------------------------CAAGTY 442
Query: 1240 GPRCQTVLSPCESQPCQHGGQCRPSPGP------GGGLTFTCHCAQPFWGPRCERVARSC 1293
GP C ++ S C +GG C P G GL T C WG C SC
Sbjct: 443 GPNCSSICS------CNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN---ESC 493
Query: 1294 RELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAA-APCLHGGSCRP 1352
C G C +P C+C PG G +C P G +C+ C H C P
Sbjct: 494 ---TCANGAAC--SPIDGSCSCTPGWLGDTCEL--PCPDGTFGLNCSEHCDCSHADGCDP 546
Query: 1353 APLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDREC---NSPG 1409
C C GWTG RC+ + C R C C N
Sbjct: 547 VT----GHCCCLAGWTGIRCD----------------STCPPGRWGPNCSVSCSCENGGS 586
Query: 1410 CGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNP 1469
C + G C + G C+ + C F C C P C++ + CH C P
Sbjct: 587 CSPEDGSCECAPGFRGPLCQRI-CPPGFYGHGCAQPC--PLCVHSSRPCHHISGICECLP 643
Query: 1470 VY-----EKYCADHFADGRCDQGC---NTEEC-----------GWDGLDCASEVP 1505
+ + CA + C Q C N C GW G DC+ P
Sbjct: 644 GFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACP 698
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 269 bits (688), Expect = 2e-71
Identities = 128/326 (39%), Positives = 172/326 (52%), Gaps = 22/326 (6%)
Query: 376 ICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVN--TQGSFLCQCGRGYTGPRCETDVN 433
+ TC PG E C G+C ++ +F C C Y G CE + +
Sbjct: 304 VSTCVPG-----------ESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYD 351
Query: 434 ECLSGPCRNQATCLDRI-----GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRV 488
C PC+N A+C+D FTC+C+ G+TG C+ ID C PC NG C +
Sbjct: 352 ACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSL 411
Query: 489 NGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDD 548
+GF+C CP G+ GS C+ VD CAS+PC+N C + C C+ GF G C + +D
Sbjct: 412 SGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDF 471
Query: 549 CSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRC 608
C+ PC HG C S+ C C PGY G CE + +EC S PC + C DLV+ Y C C
Sbjct: 472 CALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVC 531
Query: 609 PSGTTGVNCEVNIDDCASNPCTFGVC--RDGINRYDCVCQPGFTGPLCNVEINECASSPC 666
+ G +CE+ D CA+ C G DG+N C+C PGFTG C+++INEC S+PC
Sbjct: 532 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPC 590
Query: 667 GEGGSCVDGENGFRCLCPPGSLPPLC 692
GGSC+D NG+ C CP G + C
Sbjct: 591 HHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 257 bits (657), Expect = 8e-68
Identities = 128/329 (38%), Positives = 177/329 (53%), Gaps = 27/329 (8%)
Query: 224 CLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN--TYNCQCPPEWTGQFCTEDVDECQLQ 281
C+PG E + +D C G C + T++C C ++ G FC E+ D CQ +
Sbjct: 307 CVPG------ESHANDL---ECSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQRK 356
Query: 282 PNACHNGGTCFNTL-----GGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASF 336
P C N +C + +CVC+ G+TGE C ID C C +GATC ++ F
Sbjct: 357 P--CQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGF 414
Query: 337 YCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDEC 395
C CP G G C D C S+PC + C + V+ C C PGFTG C Q +D C
Sbjct: 415 TCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVH--FTCNCSPGFTGPTCAQLIDFC 472
Query: 396 SIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC 455
++ +PC H G C + S+ C C GY G CE + NECLS PC N ATC D + + C
Sbjct: 473 AL--SPCAH-GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYEC 529
Query: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVC-KDRVNGFSCTCPSGFSGSTCQLDVDECAST 514
+C+A + GT+CE+ D C + C+NG C D +NG +C C GF+G C +D++EC S
Sbjct: 530 VCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSN 588
Query: 515 PCRNGAKCVDQPDGYECRCAEGFEGTLCD 543
PC +G C+DQP+GY C C G+ G C+
Sbjct: 589 PCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 249 bits (636), Expect = 2e-65
Identities = 121/318 (38%), Positives = 161/318 (50%), Gaps = 11/318 (3%)
Query: 308 GESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC- 366
GES + +++ C T A+F C C G C DAC PC +A C
Sbjct: 310 GESHANDLECSGKGKC----TTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCI 365
Query: 367 DTNPVNGRA--ICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYT 424
D N + C C PG+TG C +D C + +PC + C+++ F CQC GY
Sbjct: 366 DANEKQDGSNFTCVCLPGYTGELCQSKIDYCIL--DPCRNGATCISSLSGFTCQCPEGYF 423
Query: 425 GPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVC 484
G CE V+ C S PC+N TC FTC C GFTG C ID C SPC +G C
Sbjct: 424 GSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TC 482
Query: 485 KDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544
+ + C C G+ G C+ + +EC S PC N A C D +GYEC C ++GT C+
Sbjct: 483 RSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCEL 542
Query: 545 NVDDCSPDPCHHGRCVDGIA-SFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
D C+ C +G D + +C CAPG+TG C+ ++EC S PC HGG CLD +
Sbjct: 543 YKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNG 602
Query: 604 YLCRCPSGTTGVNCEVNI 621
Y C CP G G NCE+++
Sbjct: 603 YNCHCPHGWVGANCEIHL 620
Score = 240 bits (613), Expect = 1e-62
Identities = 115/323 (35%), Positives = 155/323 (47%), Gaps = 18/323 (5%)
Query: 720 CEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779
C PG S + + C ++P A F CTC G CE C P
Sbjct: 307 CVPGESHANDLECSGKGKCTTKPSEAT---------FSCTCEEQYVGTFCEEYDACQRKP 357
Query: 780 CEHGGRC----ESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC 835
C++ C E G C C G+ G CQ +D C PC C + F+C
Sbjct: 358 CQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILD-PCRNGATCISSLSGFTC 416
Query: 836 TCHGGYTGPSCDQDINDCDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRCARDVDECLSN 894
C GY G +C++ ++ C +PC N G+C DGV F+C+C PGF GP CA+ +D C +
Sbjct: 417 QCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQLIDFCALS 475
Query: 895 PCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY 954
PC GTC S+ C C PGY G +CE++ +C + C N TC D VN + C+C Y
Sbjct: 476 PCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEY 535
Query: 955 TGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGR 1014
G HC+ DPC + CL+G C + C C FTG +C ++ C PC +GG
Sbjct: 536 KGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGS 595
Query: 1015 CVQ--TGAYCLCPPGWSGRLCDI 1035
C+ G C CP GW G C+I
Sbjct: 596 CLDQPNGYNCHCPHGWVGANCEI 618
Score = 233 bits (593), Expect = 2e-60
Identities = 121/308 (39%), Positives = 156/308 (50%), Gaps = 14/308 (4%)
Query: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARC---SVGPDG-RF 142
C+G+G C + A FSC C + G C D C PC + A C + DG F
Sbjct: 319 CSGKGKCTTK--PSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNF 376
Query: 143 LCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCA 202
C C PGY G C+S +D C + +PCR+G TC+++ F CQCP GY G CE PCA
Sbjct: 377 TCVCLPGYTGELCQSKIDYC-ILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCA 435
Query: 203 PSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQC 262
SPC+N GTC G + + C C PGF G C +D C C + GTC +Y C C
Sbjct: 436 SSPCQNNGTCYVDG-VHFTCNCSPGFTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKCLC 493
Query: 263 PPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV 322
P + G +C E+ +EC P C N TC + + G+ CVC+ + G C D CA
Sbjct: 494 DPGYHGLYCEEEYNECLSAP--CLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVS 551
Query: 323 CFHGATCHDRVASFYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPP 381
C +GATC + C C G TG C +D + C SNPCH C P NG C CP
Sbjct: 552 CLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQP-NGYN-CHCPH 609
Query: 382 GFTGGACD 389
G+ G C+
Sbjct: 610 GWVGANCE 617
Score = 232 bits (591), Expect = 4e-60
Identities = 115/312 (36%), Positives = 151/312 (48%), Gaps = 20/312 (6%)
Query: 858 CLNGGSC--QDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTD-----HVASFT 909
C G C + +FSC+C + G C + D C PC +C D ++FT
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSR 969
C C PGY G C+ + C C NG TC+ ++ F+C C GY G+ C+ + DPC S
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASS 437
Query: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGG-RCVQTGAYCLCPPGW 1028
PC + G C F C C FTGP C L+D+C+ PC +G R V T CLC PG+
Sbjct: 438 PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGY 497
Query: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC 1088
G C+ C A C C D + + CVC G+HCE DPC
Sbjct: 498 HGLYCEEEYNECLSAP----------CLNAATCRDLVNGYECVCLAEYKGTHCELYKDPC 547
Query: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSC 1148
C +G TC C C PG+ G+ C+ D++EC S PC HGGSC+D Y C C
Sbjct: 548 ANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHC 607
Query: 1149 PPGTLGVLCEIN 1160
P G +G CEI+
Sbjct: 608 PHGWVGANCEIH 619
Score = 226 bits (575), Expect = 3e-58
Identities = 125/344 (36%), Positives = 171/344 (49%), Gaps = 46/344 (13%)
Query: 874 SCLPGFAGPRCARDVDECLSNPCGPGTCTDHV--ASFTCTCPPGYGGFHCEQDLPDCSPS 931
+C+PG + A D+ EC G G CT A+F+CTC Y G CE+ C
Sbjct: 306 TCVPGESH---ANDL-EC----SGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRK 356
Query: 932 SCFNGGTCVDGV-----NSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 986
C N +C+D ++F+C+C PGYTG CQ + D C+ PC +G C ++ GF C
Sbjct: 357 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTC 416
Query: 987 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY--CLCPPGWSGRLC----DIRSL-P 1039
C E + G C+ VD C+ PCQN G C G + C C PG++G C D +L P
Sbjct: 417 QCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP 476
Query: 1040 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC 1099
C A G C +S+ C+C G G +CE+E + CL+ PC + TC
Sbjct: 477 C----------------AHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATC 520
Query: 1100 RGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
R + GY C CL Y G +CE D CA+ C +G +C C C PG G C+I
Sbjct: 521 RDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDI 580
Query: 1160 NEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
+ ++C DS P C H G+C+D G+ C CP G+ G CE
Sbjct: 581 DINEC------DSNP-CHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 225 bits (573), Expect = 4e-58
Identities = 120/325 (36%), Positives = 162/325 (49%), Gaps = 18/325 (5%)
Query: 692 CLP-PSHPCAHEPCSHGICYDAPGG--FRCVCEPGWSGPRCSQSLARDACESQPCRAGGT 748
C+P SH E G C P F C CE + G C + DAC+ +PC+ +
Sbjct: 307 CVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCEEY---DACQRKPCQNNAS 363
Query: 749 C-----SSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGW 802
C DG F C C PG G C+ + C +PC +G C S+ C CP+G+
Sbjct: 364 CIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGF-TCQCPEGY 422
Query: 803 QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGG 862
G C++ VD CA +PC +G C F+C C G+TGP+C Q I+ C +PC +G
Sbjct: 423 FGSACEEKVDPCAS-SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG- 480
Query: 863 SCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHC 921
+C+ S+ C C PG+ G C + +ECLS PC TC D V + C C Y G HC
Sbjct: 481 TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHC 540
Query: 922 EQDLPDCSPSSCFNGGTC-VDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
E C+ SC NG TC DG+N +C+C PG+TG C + + C S PC HGG C
Sbjct: 541 ELYKDPCANVSCLNGATCDSDGLNG-TCICAPGFTGEECDIDINECDSNPCHHGGSCLDQ 599
Query: 981 HPGFRCTCLESFTGPQCQTLVDWCS 1005
G+ C C + G C+ + W S
Sbjct: 600 PNGYNCHCPHGWVGANCEIHLQWKS 624
Score = 219 bits (557), Expect = 3e-56
Identities = 115/306 (37%), Positives = 150/306 (49%), Gaps = 9/306 (2%)
Query: 49 CANGGRCTQLPSREA-ACLCPPGWVGERCQLEDPCHSGPCAGRGVC-QSSVVAGTARFSC 106
C+ G+CT PS +C C +VG C+ D C PC C ++ + F+C
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKPCQNNASCIDANEKQDGSNFTC 378
Query: 107 RCPRGFRGPDC-SLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
C G+ G C S D C+ PC +GA C G F C CP GY G +C VD C
Sbjct: 379 VCLPGYTGELCQSKIDYCILDPCRNGATCISSLSG-FTCQCPEGYFGSACEEKVDPC-AS 436
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL 225
PC++ GTC F C C G+TGP C CA SPC +G TCR G +Y C C
Sbjct: 437 SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGT-SYKCLCD 494
Query: 226 PGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNAC 285
PG+ G CE ++C CLN TC D VN Y C C E+ G C D C +C
Sbjct: 495 PGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANV--SC 552
Query: 286 HNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKT 345
NG TC + +C+C G+TGE C +I++C + C HG +C D+ + C CP G
Sbjct: 553 LNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWV 612
Query: 346 GLLCHL 351
G C +
Sbjct: 613 GANCEI 618
Score = 202 bits (515), Expect = 2e-51
Identities = 109/320 (34%), Positives = 151/320 (47%), Gaps = 24/320 (7%)
Query: 546 VDDCSPDPCH--------HGRCVD--GIASFSCACAPGYTGTRCESQVDECRSQPCRHGG 595
V C P H G+C A+FSC C Y GT CE + D C+ +PC++
Sbjct: 304 VSTCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNA 362
Query: 596 KCLDLVDK-----YLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGF 649
C+D +K + C C G TG C+ ID C +PC G C ++ + C C G+
Sbjct: 363 SCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGY 422
Query: 650 TGPLCNVEINECASSPCGEGGSC-VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI 708
G C +++ CASSPC G+C VDG + F C C PG P C CA PC+HG
Sbjct: 423 FGSACEEKVDPCASSPCQNNGTCYVDGVH-FTCNCSPGFTGPTCAQLIDFCALSPCAHGT 481
Query: 709 CYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ 768
C ++C+C+PG+ G C + + C S PC TC G+ C C +G
Sbjct: 482 CRSVGTSYKCLCDPGYHGLYCEEEY--NECLSAPCLNAATCRDLVNGYECVCLAEYKGTH 539
Query: 769 CELL-SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT 827
CEL PC C +G C+S G C C G+ G C D++EC PC G C
Sbjct: 540 CELYKDPCANVSCLNGATCDS-DGLNGTCICAPGFTGEECDIDINEC-DSNPCHHGGSCL 597
Query: 828 NLAGSFSCTCHGGYTGPSCD 847
+ ++C C G+ G +C+
Sbjct: 598 DQPNGYNCHCPHGWVGANCE 617
Score = 202 bits (514), Expect = 3e-51
Identities = 110/326 (33%), Positives = 147/326 (45%), Gaps = 38/326 (11%)
Query: 1009 CQNGGRCV----QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD- 1063
C G+C + C C + G C+ R+ CQ C+D
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEEYDACQRKP-----------CQNNASCIDA 367
Query: 1064 ---EDSSHY-CVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
+D S++ CVC G TG C+ ++D C+ PC++G TC + G+ C+C GY G C
Sbjct: 368 NEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSAC 427
Query: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
E+ VD CAS PCQ+ G+C + C+C PG G C D C P C H
Sbjct: 428 EEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSP-------CAH- 479
Query: 1180 GTCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHTRDCLQDPGGGFRCLCHAGF 1238
GTC + ++C C PGY GL CE + NEC S C +AA RD + G+ C+C A +
Sbjct: 480 GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLV----NGYECVCLAEY 535
Query: 1239 SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQC 1298
G C+ PC + C +G C GL TC CA F G C+ C C
Sbjct: 536 KGTHCELYKDPCANVSCLNGATC-----DSDGLNGTCICAPGFTGEECDIDINECDSNPC 590
Query: 1299 PVGVPCQQTPRGPRCACPPGLSGPSC 1324
G C P G C CP G G +C
Sbjct: 591 HHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 152 bits (383), Expect = 5e-36
Identities = 99/319 (31%), Positives = 127/319 (39%), Gaps = 39/319 (12%)
Query: 1106 YMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVAR-----YLCSCPPGTLGVLCEIN 1160
+ C C Y G CE+ D C +PCQ+ SCID + + C C PG G LC+
Sbjct: 334 FSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 1161 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTR 1220
D C P C + TC+ + GF C CP GY G CE ++ C S C T
Sbjct: 393 IDYCILDP-------CRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGT- 444
Query: 1221 DCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQP 1280
C D G F C C GF+GP C ++ C PC HG CR G ++ C C
Sbjct: 445 -CYVD-GVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSV-----GTSYKCLCDPG 496
Query: 1281 FWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCA 1340
+ G CE C C C+ G C C G C + CA
Sbjct: 497 YHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELY--------KDPCA 548
Query: 1341 AAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQR 1400
CL+G +C L C CA G+TG C+ E P +C DQ
Sbjct: 549 NVSCLNGATCDSDGLNG--TCICAPGFTGEECDID--INECDSNPCHHGGSCL----DQP 600
Query: 1401 CDRECNSPGCGWDGGDCSL 1419
C+ P GW G +C +
Sbjct: 601 NGYNCHCPH-GWVGANCEI 618
Score = 135 bits (339), Expect = 6e-31
Identities = 82/236 (34%), Positives = 98/236 (41%), Gaps = 49/236 (20%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFSC 106
PC NG C S C CP G+ G C+ + DPC S PC G C V F+C
Sbjct: 400 PCRNGATCISSLSG-FTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGV----HFTC 454
Query: 107 RCPRGFRGPDCS-LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
C GF GP C+ L D C SPCAHG SVG + C C PGY G C + +EC +
Sbjct: 455 NCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTS--YKCLCDPGYHGLYCEEEYNEC-LS 511
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL 225
PC + TC + + C C A Y G CE PCA C NG TC G L C C
Sbjct: 512 APCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDG-LNGTCICA 570
Query: 226 PGFEGQ--------------------------------------NCEVNVDDCPGH 243
PGF G+ NCE+++ GH
Sbjct: 571 PGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEIHLQWKSGH 626
Score = 80.9 bits (198), Expect = 1e-14
Identities = 38/87 (43%), Positives = 47/87 (54%), Gaps = 15/87 (17%)
Query: 473 CQSSPCVNGGVCKDRVN------------GFSCTCPSGFSGSTCQLDVDECASTPCRNG- 519
C + PC NGGVC R G+SCTCP+G SG+ CQL D CAS PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 520 --AKCVDQPDGYECRCAEGFEGTLCDR 544
+ DGY C C EG+EG C++
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 75.1 bits (183), Expect = 7e-13
Identities = 58/161 (36%), Positives = 66/161 (40%), Gaps = 49/161 (30%)
Query: 12 RRPMSPPPPPPPVRALPLLLLLAGPGA--------AAP-----PCLDGSPCANGGRCTQL 58
RR +P P AL LLLL AGP AAP PC PC NGG CT
Sbjct: 4 RRAQAPGAQLLPALALLLLLLGAGPRGSSLANPVPAAPLSAPGPCA-AQPCRNGGVCTSR 62
Query: 59 PSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS 118
P DP H P AG +SC CP G G +C
Sbjct: 63 PE------------------PDPQHPAP------------AGEPGYSCTCPAGISGANCQ 92
Query: 119 L-PDPCLSSPCAHG---ARCSVGPDGRFLCSCPPGYQGRSC 155
L DPC S+PC HG + S DG +LC C GY+G +C
Sbjct: 93 LVADPCASNPCHHGNCSSSSSSSSDG-YLCICNEGYEGPNC 132
Score = 73.2 bits (178), Expect = 3e-12
Identities = 34/88 (38%), Positives = 47/88 (53%), Gaps = 17/88 (19%)
Query: 738 CESQPCRAGGTCSS------------DGMGFHCTCPPGVQGRQCELLS-PCTPNPCEHGG 784
C +QPCR GG C+S G+ CTCP G+ G C+L++ PC NPC H G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH-G 106
Query: 785 RCESAPGQLP---VCSCPQGWQGPRCQQ 809
C S+ +C C +G++GP C+Q
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 72.4 bits (176), Expect = 5e-12
Identities = 33/86 (38%), Positives = 39/86 (45%), Gaps = 16/86 (18%)
Query: 511 CASTPCRNGAKCVDQPD------------GYECRCAEGFEGTLCDRNVDDCSPDPCHHGR 558
CA+ PCRNG C +P+ GY C C G G C D C+ +PCHHG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 559 CVDGIASFS----CACAPGYTGTRCE 580
C +S S C C GY G CE
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 69.7 bits (169), Expect = 3e-11
Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 16/85 (18%)
Query: 586 CRSQPCRHGGKCLDLVDK------------YLCRCPSGTTGVNCEVNIDDCASNPCTFGV 633
C +QPCR+GG C + Y C CP+G +G NC++ D CASNPC G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 634 CRDGINR----YDCVCQPGFTGPLC 654
C + Y C+C G+ GP C
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 68.6 bits (166), Expect = 7e-11
Identities = 32/89 (35%), Positives = 40/89 (44%), Gaps = 16/89 (17%)
Query: 661 CASSPCGEGGSCVD------------GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI 708
CA+ PC GG C GE G+ C CP G C + PCA PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 709 CYDAPG----GFRCVCEPGWSGPRCSQSL 733
C + G+ C+C G+ GP C Q+L
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 67.4 bits (163), Expect = 2e-10
Identities = 32/86 (37%), Positives = 41/86 (47%), Gaps = 15/86 (17%)
Query: 928 CSPSSCFNGGTCVD------------GVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGG 975
C+ C NGG C G +SC C G +GA+CQ ADPC S PC HG
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 976 V---CSAAHPGFRCTCLESFTGPQCQ 998
S++ G+ C C E + GP C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 65.5 bits (158), Expect = 6e-10
Identities = 32/90 (35%), Positives = 43/90 (47%), Gaps = 14/90 (15%)
Query: 166 EPCRHGGTCLNTPG------------SFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCR 213
+PCR+GG C + P + C CPAG +G C+ A PCA +PC +G
Sbjct: 51 QPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSS 110
Query: 214 QSGDLT--YDCACLPGFEGQNCEVNVDDCP 241
S + Y C C G+EG NCE + P
Sbjct: 111 SSSSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 64.7 bits (156), Expect = 1e-09
Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 16/90 (17%)
Query: 853 CDPNPCLNGGSCQD------------GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900
C PC NGG C G +SC+C G +G C D C SNPC G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 901 CTDHVAS----FTCTCPPGYGGFHCEQDLP 926
C+ +S + C C GY G +CEQ LP
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQALP 137
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/90 (38%), Positives = 43/90 (47%), Gaps = 17/90 (18%)
Query: 774 PCTPNPCEHGGRCESAPGQLPV-----------CSCPQGWQGPRCQQDVDECAGPAPCGP 822
PC PC +GG C S P P C+CP G G CQ D CA PC
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASN-PCH- 104
Query: 823 HGICTNLAGSFS----CTCHGGYTGPSCDQ 848
HG C++ + S S C C+ GY GP+C+Q
Sbjct: 105 HGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 62.8 bits (151), Expect = 4e-09
Identities = 35/120 (29%), Positives = 48/120 (40%), Gaps = 37/120 (30%)
Query: 1004 CSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD 1063
C+ QPC+NGG +C R P + A G
Sbjct: 48 CAAQPCRNGG------------------VCTSRPEPDPQHPAPAG--------------- 74
Query: 1064 EDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHG---GTCRGYMGGYMCECLPGYNGDNCE 1120
+ + C CP G +G++C+ DPC + PC HG + GY+C C GY G NCE
Sbjct: 75 -EPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 62.0 bits (149), Expect = 7e-09
Identities = 33/101 (32%), Positives = 46/101 (45%), Gaps = 16/101 (15%)
Query: 118 SLPDPCLSSPCAHGARCSVGP-----------DGRFLCSCPPGYQGRSCRSDVDECRVGE 166
S P PC + PC +G C+ P + + C+CP G G +C+ D C
Sbjct: 43 SAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPC-ASN 101
Query: 167 PCRHGGTCLNTPGS---FRCQCPAGYTGPLCENPAVPCAPS 204
PC HG ++ S + C C GY GP CE A+P P+
Sbjct: 102 PCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ-ALPSLPA 141
Score = 62.0 bits (149), Expect = 7e-09
Identities = 34/87 (39%), Positives = 38/87 (43%), Gaps = 15/87 (17%)
Query: 1087 PCLAQPCQHGGTCRGYMG------------GYMCECLPGYNGDNCEDDVDECASQPCQHG 1134
PC AQPC++GG C GY C C G +G NC+ D CAS PC HG
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 1135 ---GSCIDLVARYLCSCPPGTLGVLCE 1158
S YLC C G G CE
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 61.6 bits (148), Expect = 9e-09
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 19/94 (20%)
Query: 965 PCLSRPCLHGGVCS------------AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNG 1012
PC ++PC +GGVC+ A PG+ CTC +G CQ + D C+ PC +G
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 1013 -----GRCVQTGAYCLCPPGWSGRLCD--IRSLP 1039
G C+C G+ G C+ + SLP
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 61.2 bits (147), Expect = 1e-08
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 33/122 (27%)
Query: 1126 CASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDL 1185
CA+QPC++GG C + + P P +G
Sbjct: 48 CAAQPCRNGGVCT---------------------SRPEPDPQHPAPAGEP---------- 76
Query: 1186 VGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQT 1245
G+ CTCP G +G C+ + C S CH + G+ C+C+ G+ GP C+
Sbjct: 77 --GYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Query: 1246 VL 1247
L
Sbjct: 135 AL 136
Score = 59.7 bits (143), Expect = 3e-08
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 6/88 (6%)
Query: 1209 CRSGACHAAHTRDCLQDPGG----GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPS 1264
CR+G + Q P G+ C C AG SG CQ V PC S PC HG S
Sbjct: 53 CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSS 112
Query: 1265 PGPGGGLTFTCHCAQPFWGPRCERVARS 1292
G + C C + + GP CE+ S
Sbjct: 113 SSSSDG--YLCICNEGYEGPNCEQALPS 138
Score = 58.5 bits (140), Expect = 7e-08
Identities = 38/112 (33%), Positives = 44/112 (39%), Gaps = 20/112 (17%)
Query: 682 LCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPG------------GFRCVCEPGWSGPR 728
L P PL P PCA +PC +G +C P G+ C C G SG
Sbjct: 33 LANPVPAAPLSAPG--PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGAN 90
Query: 729 CSQSLARDACESQPCRAGGTCSSDGM---GFHCTCPPGVQGRQCELLSPCTP 777
C L D C S PC G SS G+ C C G +G CE P P
Sbjct: 91 CQ--LVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLP 140
Score = 56.6 bits (135), Expect = 3e-07
Identities = 37/128 (28%), Positives = 50/128 (39%), Gaps = 44/128 (34%)
Query: 1249 PCESQPCQHGGQC--RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQ 1306
PC +QPC++GG C RP P P + P G P
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDP---------------------------QHPAPAGEP--- 76
Query: 1307 TPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGG-SCRPAPLAPFFRCACAQ 1365
G C CP G+SG +C+ CA+ PC HG S + + + C C +
Sbjct: 77 ---GYSCTCPAGISGANCQLVADP--------CASNPCHHGNCSSSSSSSSDGYLCICNE 125
Query: 1366 GWTGPRCE 1373
G+ GP CE
Sbjct: 126 GYEGPNCE 133
Score = 55.1 bits (131), Expect = 8e-07
Identities = 34/109 (31%), Positives = 42/109 (38%), Gaps = 26/109 (23%)
Query: 200 PCAPSPCRNGGTCRQ-----------SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNG 248
PCA PCRNGG C +G+ Y C C G G NC++ D C + C +G
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHG 106
Query: 249 G--------------TCVDGVNTYNC-QCPPEWTGQFCTEDVDECQLQP 282
C +G NC Q P TE + QLQP
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQP 155
Score = 53.5 bits (127), Expect = 2e-06
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 15/86 (17%)
Query: 435 CLSGPCRNQATCLDR----------IGQ--FTCICMAGFTGTYCEVDIDECQSSPCVNGG 482
C + PCRN C R G+ ++C C AG +G C++ D C S+PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 483 V---CKDRVNGFSCTCPSGFSGSTCQ 505
+G+ C C G+ G C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 47.4 bits (111), Expect = 2e-04
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 16/86 (18%)
Query: 891 CLSNPC-GPGTCTD-------HVA-----SFTCTCPPGYGGFHCEQDLPDCSPSSCFNGG 937
C + PC G CT H A ++CTCP G G +C+ C+ + C +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 938 TCVDGVNS---FSCLCRPGYTGAHCQ 960
+S + C+C GY G +C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 47.0 bits (110), Expect = 2e-04
Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 14/87 (16%)
Query: 318 CATAVCFHGATCHDRVA------------SFYCACPMGKTGLLCHL-DDACVSNPCHE-D 363
CA C +G C R + C CP G +G C L D C SNPCH +
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 364 AICDTNPVNGRAICTCPPGFTGGACDQ 390
++ + +C C G+ G C+Q
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 42.4 bits (98), Expect = 0.005
Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 19/88 (21%)
Query: 278 CQLQPNACHNGGTCFNTLG------------GHSCVCVNGWTGESCSQNIDDCATAVCFH 325
C QP C NGG C + G+SC C G +G +C D CA+ C H
Sbjct: 48 CAAQP--CRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 326 GATCHDRVAS----FYCACPMGKTGLLC 349
G C +S + C C G G C
Sbjct: 106 G-NCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 40.8 bits (94), Expect = 0.016
Identities = 24/101 (23%), Positives = 36/101 (35%), Gaps = 11/101 (10%)
Query: 370 PVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE 429
P++ C P GG C + P G + C C G +G C+
Sbjct: 41 PLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPG--------YSCTCPAGISGANCQ 92
Query: 430 TDVNECLSGPCRN---QATCLDRIGQFTCICMAGFTGTYCE 467
+ C S PC + ++ + CIC G+ G CE
Sbjct: 93 LVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 40.4 bits (93), Expect = 0.020
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 33 LAGPGAAAPPC------LDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP 86
+ PG C D +PC +GG C P+ C CP GWVG C++ SG
Sbjct: 568 ICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYN-CHCPHGWVGANCEIHLQWKSGH 626
Query: 87 CA 88
A
Sbjct: 627 MA 628
Score = 38.1 bits (87), Expect = 0.10
Identities = 47/178 (26%), Positives = 61/178 (34%), Gaps = 42/178 (23%)
Query: 1332 PGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAA 1391
PG S+A+ C G C P F C C + + G CE E C R
Sbjct: 309 PGESHAN--DLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE---------EYDACQRKP 357
Query: 1392 CQ--AKRGDQRCDRECNSPGC----GWDGGDCSLSVG----DPWRQCE---------ALQ 1432
CQ A D ++ ++ C G+ G C + DP R Q
Sbjct: 358 CQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQ 417
Query: 1433 CWRLFNNSRC----DPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQ 1486
C + S C DP SSP +N C+ G TCN C+ F C Q
Sbjct: 418 CPEGYFGSACEEKVDPCASSPC--QNNGTCYVDGVHFTCN------CSPGFTGPTCAQ 467
Score = 37.0 bits (84), Expect = 0.23
Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 21/113 (18%)
Query: 1320 SGPSCRSFPGSPPGASNAS---CAAAPCLHGGSC---------RPAPLA-PFFRCACAQG 1366
+GP S P A ++ CAA PC +GG C PAP P + C C G
Sbjct: 26 AGPRGSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAG 85
Query: 1367 WTGPRCE--APAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDC 1417
+G C+ A A C ++ + G C CN G++G +C
Sbjct: 86 ISGANCQLVADPCASNPCHHGNCSSSSSSSSDG-YLC--ICNE---GYEGPNC 132
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 268 bits (685), Expect = 5e-71
Identities = 140/356 (39%), Positives = 179/356 (50%), Gaps = 29/356 (8%)
Query: 711 DAPGGFRC------VCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGV 764
DA G F C VC PGW GP C++ + C+ Q G C G C C G
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH----GFCDKPG---ECKCRVGW 249
Query: 765 QGRQCELLSPCTPNP-CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPH 823
QGR C+ C P C HG C+ P Q C+C +GW G C QD++ C PC
Sbjct: 250 QGRYCD---ECIRYPGCLHG-TCQQ-PWQ---CNCQEGWGGLFCNQDLNYCTHHKPCKNG 301
Query: 824 GICTNLA-GSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGP 882
CTN GS++C+C GYTG +C+ I++CDP+PC NGGSC D S+SC+C PGF G
Sbjct: 302 ATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGK 361
Query: 883 RCARDVDECLSNPC-GPGTCTDHV-ASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCV 940
C C PC G C+D ++C CP GY GF+CE+ + CS S C NG CV
Sbjct: 362 ICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCV 421
Query: 941 DGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTL 1000
D +++ C C+ G++G HC D C S PC +GG C F CTC +TG C
Sbjct: 422 DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAP 481
Query: 1001 VDWCSRQPCQNGGRCVQTG--AYCLCPPGWSGRLCD--IRSLPCREAAAQIGVRLE 1052
V C PC NG C + G C C G+ G C + LP A + +LE
Sbjct: 482 VSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLTEKLE 537
Score = 265 bits (676), Expect = 5e-70
Identities = 132/331 (39%), Positives = 170/331 (51%), Gaps = 17/331 (5%)
Query: 301 VCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360
VC GW G C++ I C C D+ C C +G G C D C+ P
Sbjct: 211 VCNPGWKGPYCTEPI--CLPGCDEQHGFC-DKPGE--CKCRVGWQGRYC---DECIRYPG 262
Query: 361 HEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNT-QGSFLCQC 419
C P C C G+ G C+QD++ C+ PC++ C NT QGS+ C C
Sbjct: 263 CLHGTCQ-QPWQ----CNCQEGWGGLFCNQDLNYCT-HHKPCKNGATCTNTGQGSYTCSC 316
Query: 420 GRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCV 479
GYTG CE ++EC PC+N +C D ++C C GF G CE+ C PC
Sbjct: 317 RPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCF 376
Query: 480 NGGVCKDRVNG-FSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFE 538
NGG C D +G +SC CP G+SG C+ +D C+S+PC NGAKCVD D Y CRC GF
Sbjct: 377 NGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFS 436
Query: 539 GTLCDRNVDDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKC 597
G CD NVDDC+ PC +G C DG+ FSC C PGYTG C + V C PC +G C
Sbjct: 437 GRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATC 496
Query: 598 LDLVDKYLCRCPSGTTGVNCEVNIDDCASNP 628
+ +Y+C C G G NC+ + + P
Sbjct: 497 HERGHRYVCECARGYGGPNCQFLLPELPPGP 527
Score = 259 bits (661), Expect = 3e-68
Identities = 145/373 (38%), Positives = 183/373 (49%), Gaps = 31/373 (8%)
Query: 301 VCVNGWTGESCS---QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 357
VC + GE CS + DD F TC +R C G G C + C+
Sbjct: 178 VCDEHYYGEGCSVFCRPRDDA-----FGHFTCGERGEK---VCNPGWKGPYC-TEPICLP 228
Query: 358 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 417
+ CD C C G+ G CD EC I C H G C Q + C
Sbjct: 229 GCDEQHGFCDKP-----GECKCRVGWQGRYCD----EC-IRYPGCLH-GTC---QQPWQC 274
Query: 418 QCGRGYTGPRCETDVNECLSG-PCRNQATCLDR-IGQFTCICMAGFTGTYCEVDIDECQS 475
C G+ G C D+N C PC+N ATC + G +TC C G+TG CE+ IDEC
Sbjct: 275 NCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDP 334
Query: 476 SPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG-YECRCA 534
SPC NGG C D N +SCTCP GF G C+L CA PC NG +C D PDG Y CRC
Sbjct: 335 SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCP 394
Query: 535 EGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRH 593
G+ G C++ +D CS PC +G +CVD ++ C C G++G C+ VD+C S PC +
Sbjct: 395 VGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN 454
Query: 594 GGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGFTGP 652
GG C D V+ + C CP G TG NC + C PC G C + +RY C C G+ GP
Sbjct: 455 GGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGP 514
Query: 653 LCNVEINECASSP 665
C + E P
Sbjct: 515 NCQFLLPELPPGP 527
Score = 254 bits (650), Expect = 5e-67
Identities = 125/328 (38%), Positives = 179/328 (54%), Gaps = 25/328 (7%)
Query: 379 CPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG 438
C PG+ G C + + C G + E G C + G C+C G+ G C+ EC+
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCD--EQHGFC-DKPGE--CKCRVGWQGRYCD----ECIRY 260
Query: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC-QSSPCVNGGVCKDRVNG-FSCTCP 496
P TC + C C G+ G +C D++ C PC NG C + G ++C+C
Sbjct: 261 PGCLHGTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCR 317
Query: 497 SGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHH 556
G++G+TC+L +DEC +PC+NG C D + Y C C GF G +C+ + C+ PC +
Sbjct: 318 PGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFN 377
Query: 557 G-RCVDGI-ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTG 614
G RC D +SC C GY+G CE ++D C S PC +G KC+DL D YLCRC +G +G
Sbjct: 378 GGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSG 437
Query: 615 VNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCV 673
+C+ N+DDCAS+PC G CRDG+N + C C PG+TG C+ ++ C +PC G +C
Sbjct: 438 RHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCH 497
Query: 674 DGENGFRCLCPPGSLPPLC------LPP 695
+ + + C C G P C LPP
Sbjct: 498 ERGHRYVCECARGYGGPNCQFLLPELPP 525
Score = 251 bits (641), Expect = 6e-66
Identities = 136/356 (38%), Positives = 178/356 (50%), Gaps = 32/356 (8%)
Query: 388 CDQDV--DECSIGANPCEHLGRCVNTQGSFLCQ------CGRGYTGPRCETDVNECLSGP 439
CD+ + CS+ P + + G F C C G+ GP C + CL G
Sbjct: 179 CDEHYYGEGCSVFCRPRD------DAFGHFTCGERGEKVCNPGWKGPYCTEPI--CLPG- 229
Query: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF 499
C Q D+ G+ C C G+ G YC DEC P G C+ + C C G+
Sbjct: 230 CDEQHGFCDKPGE--CKCRVGWQGRYC----DECIRYPGCLHGTCQQP---WQCNCQEGW 280
Query: 500 SGSTCQLDVDECAS-TPCRNGAKCVDQPDG-YECRCAEGFEGTLCDRNVDDCSPDPCHHG 557
G C D++ C PC+NGA C + G Y C C G+ G C+ +D+C P PC +G
Sbjct: 281 GGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNG 340
Query: 558 -RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK-YLCRCPSGTTGV 615
C D S+SC C PG+ G CE C PC +GG+C D D Y CRCP G +G
Sbjct: 341 GSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGF 400
Query: 616 NCEVNIDDCASNPCTFGV-CRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVD 674
NCE ID C+S+PC+ G C D + Y C CQ GF+G C+ +++CASSPC GG+C D
Sbjct: 401 NCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRD 460
Query: 675 GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRC 729
G N F C CPPG C P C H PC +G C++ + C C G+ GP C
Sbjct: 461 GVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 244 bits (624), Expect = 5e-64
Identities = 139/381 (36%), Positives = 185/381 (48%), Gaps = 34/381 (8%)
Query: 180 SFRCQCPAGYTGPLCENPAVPCAPSPCRNGG-TCRQSGDLTYDCACLPGFEGQNCEVNVD 238
S+R C Y G C +V C P G TC + G+ C PG++G C +
Sbjct: 174 SYRFVCDEHYYGEGC---SVFCRPRDDAFGHFTCGERGEKV----CNPGWKGPYCTEPI- 225
Query: 239 DCPGHRCLNGGTCVDGV--NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
CL G G C+C W G++C DEC P H GTC
Sbjct: 226 ------CLPGCDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGCLH--GTCQQPW- 272
Query: 297 GHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDR-VASFYCACPMGKTGLLCHLD-D 353
C C GW G C+Q+++ C C +GATC + S+ C+C G TG C L D
Sbjct: 273 --QCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID 330
Query: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNT-Q 412
C +PC C + CTCPPGF G C+ C+ G PC + GRC ++
Sbjct: 331 ECDPSPCKNGGSC--TDLENSYSCTCPPGFYGKICELSAMTCADG--PCFNGGRCSDSPD 386
Query: 413 GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE 472
G + C+C GY+G CE ++ C S PC N A C+D + C C AGF+G +C+ ++D+
Sbjct: 387 GGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDD 446
Query: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECR 532
C SSPC NGG C+D VN FSCTCP G++G C V C PC NGA C ++ Y C
Sbjct: 447 CASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCE 506
Query: 533 CAEGFEGTLCDRNVDDCSPDP 553
CA G+ G C + + P P
Sbjct: 507 CARGYGGPNCQFLLPELPPGP 527
Score = 238 bits (608), Expect = 4e-62
Identities = 135/380 (35%), Positives = 176/380 (46%), Gaps = 40/380 (10%)
Query: 798 CPQGWQGPRCQ---QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
C + + G C + D+ G CG G C+ G+ GP C + I C
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGERG---------EKVCNPGWKGPYCTEPI--CL 227
Query: 855 PNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNP-CGPGTCTDHVASFTCTCP 913
P G C D G C C G+ G C DEC+ P C GTC + C C
Sbjct: 228 PGCDEQHGFC-DKPGE--CKCRVGWQGRYC----DECIRYPGCLHGTCQQ---PWQCNCQ 277
Query: 914 PGYGGFHCEQDLPDCSPSS-CFNGGTCVD-GVNSFSCLCRPGYTGAHCQHEADPCLSRPC 971
G+GG C QDL C+ C NG TC + G S++C CRPGYTGA C+ D C PC
Sbjct: 278 EGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPC 337
Query: 972 LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT---GAYCLCPPGW 1028
+GG C+ + CTC F G C+ C+ PC NGGRC + G C CP G+
Sbjct: 338 KNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGY 397
Query: 1029 SGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPC 1088
SG C+ + C + C G +CVD ++ C C G +G HC+ VD C
Sbjct: 398 SGFNCEKKIDYCSSSP----------CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDC 447
Query: 1089 LAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSC 1148
+ PC +GGTCR + + C C PGY G NC V C PC +G +C + RY+C C
Sbjct: 448 ASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCEC 507
Query: 1149 PPGTLGVLCEINEDDCGPGP 1168
G G C+ + PGP
Sbjct: 508 ARGYGGPNCQFLLPELPPGP 527
Score = 235 bits (600), Expect = 3e-61
Identities = 119/317 (37%), Positives = 156/317 (49%), Gaps = 20/317 (6%)
Query: 35 GPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQ 94
GP P CL G +G + C C GW G C D C P G CQ
Sbjct: 218 GPYCTEPICLPGCDEQHG-----FCDKPGECKCRVGWQGRYC---DECIRYPGCLHGTCQ 269
Query: 95 SSVVAGTARFSCRCPRGFRGPDCSLP-DPCLS-SPCAHGARCSVGPDGRFLCSCPPGYQG 152
+ C C G+ G C+ + C PC +GA C+ G + CSC PGY G
Sbjct: 270 QP-------WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTG 322
Query: 153 RSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212
+C +DEC PC++GG+C + S+ C CP G+ G +CE A+ CA PC NGG C
Sbjct: 323 ATCELGIDECDPS-PCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC 381
Query: 213 RQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 272
S D Y C C G+ G NCE +D C C NG CVD + Y C+C ++G+ C
Sbjct: 382 SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCD 441
Query: 273 EDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDR 332
++VD+C P C NGGTC + + SC C G+TG +CS + C A C +GATCH+R
Sbjct: 442 DNVDDCASSP--CANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHER 499
Query: 333 VASFYCACPMGKTGLLC 349
+ C C G G C
Sbjct: 500 GHRYVCECARGYGGPNC 516
Score = 233 bits (593), Expect = 2e-60
Identities = 139/396 (35%), Positives = 180/396 (45%), Gaps = 45/396 (11%)
Query: 219 TYDCACLPGFEGQNCEVNV---DDCPGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 274
+Y C + G+ C V DD GH C G V C P W G +CTE
Sbjct: 174 SYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKV---------CNPGWKGPYCTEP 224
Query: 275 V--DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV-CFHGATCHD 331
+ C Q C G C C GW G C D+C C HG TC
Sbjct: 225 ICLPGCDEQHGFCDKPG---------ECKCRVGWQGRYC----DECIRYPGCLHG-TCQQ 270
Query: 332 RVASFYCACPMGKTGLLCHLD-DACVSN-PCHEDAICDTNPVNGRAICTCPPGFTGGACD 389
+ C C G GL C+ D + C + PC A C TN G C+C PG+TG C+
Sbjct: 271 ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATC-TNTGQGSYTCSCRPGYTGATCE 326
Query: 390 QDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDR 449
+DEC +PC++ G C + + S+ C C G+ G CE C GPC N C D
Sbjct: 327 LGIDECD--PSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDS 384
Query: 450 I-GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
G ++C C G++G CE ID C SSPC NG C D + + C C +GFSG C +V
Sbjct: 385 PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNV 444
Query: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFS 567
D+CAS+PC NG C D + + C C G+ G C V C PCH+G C + +
Sbjct: 445 DDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYV 504
Query: 568 CACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDK 603
C CA GY G C+ + E P +DL +K
Sbjct: 505 CECARGYGGPNCQFLLPELPPGPA-----VVDLTEK 535
Score = 224 bits (570), Expect = 1e-57
Identities = 129/348 (37%), Positives = 171/348 (49%), Gaps = 38/348 (10%)
Query: 448 DRIGQFTC------ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF-----SCTCP 496
D G FTC +C G+ G YC I C+ G C D +GF C C
Sbjct: 197 DAFGHFTCGERGEKVCNPGWKGPYCTEPI-------CLPG--C-DEQHGFCDKPGECKCR 246
Query: 497 SGFSGSTCQLDVDECASTP-CRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPD-PC 554
G+ G C DEC P C +G QP ++C C EG+ G C+++++ C+ PC
Sbjct: 247 VGWQGRYC----DECIRYPGCLHGT--CQQP--WQCNCQEGWGGLFCNQDLNYCTHHKPC 298
Query: 555 HHGR-CVD-GIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 612
+G C + G S++C+C PGYTG CE +DEC PC++GG C DL + Y C CP G
Sbjct: 299 KNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGF 358
Query: 613 TGVNCEVNIDDCASNPC-TFGVCRDGINR-YDCVCQPGFTGPLCNVEINECASSPCGEGG 670
G CE++ CA PC G C D + Y C C G++G C +I+ C+SSPC G
Sbjct: 359 YGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA 418
Query: 671 SCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSGPRC 729
CVD + + C C G C CA PC++G C D F C C PG++G C
Sbjct: 419 KCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNC 478
Query: 730 SQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTP 777
S ++R CE PC G TC G + C C G G C+ L P P
Sbjct: 479 SAPVSR--CEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELP 524
Score = 217 bits (553), Expect = 9e-56
Identities = 126/352 (35%), Positives = 158/352 (44%), Gaps = 43/352 (12%)
Query: 988 CLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCD--IRSLPCREAAA 1045
C + GP C + C + G C + G C C GW GR CD IR C
Sbjct: 212 CNPGWKGPYCTEPI--CLPGCDEQHGFCDKPGE-CKCRVGWQGRYCDECIRYPGC----- 263
Query: 1046 QIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLA-QPCQHGGTCRGY-M 1103
L CQ QC C EG G C Q+++ C +PC++G TC
Sbjct: 264 -----LHGTCQQPWQCN---------CQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQ 309
Query: 1104 GGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDD 1163
G Y C C PGY G CE +DEC PC++GGSC DL Y C+CPPG G +CE++
Sbjct: 310 GSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMT 369
Query: 1164 CGPGPPLDSGPRCLHNGTCVDLV-GGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDC 1222
C GP C + G C D GG+ C CP GY+G CE I+ C S C ++ C
Sbjct: 370 CADGP-------CFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPC--SNGAKC 420
Query: 1223 LQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
+ D G + C C AGFSG C + C S PC +GG CR G F+C C +
Sbjct: 421 V-DLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCR-----DGVNDFSCTCPPGYT 474
Query: 1283 GPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR-SFPGSPPG 1333
G C C C G C + C C G GP+C+ P PPG
Sbjct: 475 GRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPG 526
Score = 194 bits (494), Expect = 6e-49
Identities = 120/397 (30%), Positives = 163/397 (41%), Gaps = 61/397 (15%)
Query: 984 FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREA 1043
+R C E + G C R C + G +C PGW G C
Sbjct: 175 YRFVCDEHYYGEGCSVFCR--PRDDAFGHFTCGERGEK-VCNPGWKGPYCT--------- 222
Query: 1044 AAQIGVRLEQLCQAGGQCVDE----DSSHYCVCPEGRTGSHCEQEVDPCLAQP-CQHGGT 1098
E +C G C ++ D C C G G +C D C+ P C HG T
Sbjct: 223 --------EPICLPG--CDEQHGFCDKPGECKCRVGWQGRYC----DECIRYPGCLHG-T 267
Query: 1099 CRGYMGGYMCECLPGYNGDNCEDDVDECAS-QPCQHGGSCIDL-VARYLCSCPPGTLGVL 1156
C+ + C C G+ G C D++ C +PC++G +C + Y CSC PG G
Sbjct: 268 CQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324
Query: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHA 1216
CE+ D+C P P C + G+C DL + CTCPPG+ G CE C G C
Sbjct: 325 CELGIDECDPSP-------CKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFN 377
Query: 1217 AHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCH 1276
C P GG+ C C G+SG C+ + C S PC +G +C G + C
Sbjct: 378 GGR--CSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDL-----GDAYLCR 430
Query: 1277 CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASN 1336
C F G C+ C C G C+ C CPPG +G +C A
Sbjct: 431 CQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNC--------SAPV 482
Query: 1337 ASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCE 1373
+ C APC +G +C + C CA+G+ GP C+
Sbjct: 483 SRCEHAPCHNGATCHER--GHRYVCECARGYGGPNCQ 517
Score = 152 bits (384), Expect = 4e-36
Identities = 103/344 (29%), Positives = 140/344 (40%), Gaps = 42/344 (12%)
Query: 1071 VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQP 1130
VC G G +C + + CL + G C C+C G+ G C DEC P
Sbjct: 211 VCNPGWKGPYCTEPI--CLPGCDEQHGFCDK---PGECKCRVGWQGRYC----DECIRYP 261
Query: 1131 -CQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1189
C HG +C + C+C G G+ C + + C P +G C + G G +
Sbjct: 262 GCLHG-TCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQ-----GSY 312
Query: 1190 RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP 1249
C+C PGYTG CE I+EC C + L++ + C C GF G C+
Sbjct: 313 TCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLEN---SYSCTCPPGFYGKICELSAMT 369
Query: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
C PC +GG+C SP G ++C C + G CE+ C C G C
Sbjct: 370 CADGPCFNGGRCSDSPDGG----YSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGD 425
Query: 1310 GPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTG 1369
C C G SG C + CA++PC +GG+CR F C C G+TG
Sbjct: 426 AYLCRCQAGFSGRHCDD--------NVDDCASSPCANGGTCRDG--VNDFSCTCPPGYTG 475
Query: 1370 PRCEAPAAAPEVSEEPRCPRAACQAKRGDQ---RCDRECNSPGC 1410
C AP + E C A +RG + C R P C
Sbjct: 476 RNCSAPVSR---CEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 129 bits (325), Expect = 3e-29
Identities = 71/170 (41%), Positives = 90/170 (52%), Gaps = 11/170 (6%)
Query: 39 AAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSV 97
+A C DG PC NGGRC+ P +C CP G+ G C+ + D C S PC+ C V
Sbjct: 366 SAMTCADG-PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKC---V 421
Query: 98 VAGTARFSCRCPRGFRGPDCS-LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
G A + CRC GF G C D C SSPCA+G C G + F C+CPPGY GR+C
Sbjct: 422 DLGDA-YLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVND-FSCTCPPGYTGRNCS 479
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE--NPAVPCAPS 204
+ V C PC +G TC + C+C GY GP C+ P +P P+
Sbjct: 480 APVSRCEHA-PCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPA 528
Score = 120 bits (301), Expect = 2e-26
Identities = 116/443 (26%), Positives = 162/443 (36%), Gaps = 86/443 (19%)
Query: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGY 1106
+G Q + G+ D S+ VC E G C C + G G G
Sbjct: 155 VGEEWSQDLHSSGR-TDLKYSYRFVCDEHYYGEGCSVF---CRPRDDAFGHFTCGERGEK 210
Query: 1107 MCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGP 1166
+C PG+ G C + + C + G C D C C G G C D+C
Sbjct: 211 VCN--PGWKGPYCTEPI--CLPGCDEQHGFC-DKPGE--CKCRVGWQGRYC----DEC-- 257
Query: 1167 GPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC-RSGACHAAHTRDCLQD 1225
P CLH GTC ++C C G+ GL C D+N C C T C
Sbjct: 258 ----IRYPGCLH-GTCQQ---PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGAT--CTNT 307
Query: 1226 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPR 1285
G + C C G++G C+ + C+ PC++GG C +++C C F+G
Sbjct: 308 GQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLEN-----SYSCTCPPGFYGKI 362
Query: 1286 CERVARSCRELQCPVGVPCQQTPRGP-RCACPPGLSGPSCRSFPGSPPGASNASCAAAPC 1344
CE A +C + C G C +P G C CP G SG +C C+++PC
Sbjct: 363 CELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEK--------KIDYCSSSPC 414
Query: 1345 LHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRE 1404
+G C L + C C G++G C D D +
Sbjct: 415 SNGAKC--VDLGDAYLCRCQAGFSGRHC-------------------------DDNVD-D 446
Query: 1405 CNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRE 1464
C S C +GG C V D C R CS+P ++ CH G
Sbjct: 447 CASSPCA-NGGTCRDGVNDFSCTCPPGYTGR---------NCSAPVSRCEHAPCHNGA-- 494
Query: 1465 RTCNPVYEKY---CADHFADGRC 1484
TC+ +Y CA + C
Sbjct: 495 -TCHERGHRYVCECARGYGGPNC 516
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 266 bits (680), Expect = 2e-70
Identities = 239/795 (30%), Positives = 302/795 (37%), Gaps = 180/795 (22%)
Query: 144 CSCPPGYQGRSCRSDVDECRV------------GEPCRHGGTC----------------L 175
C CPPG + S+V RV E C GG C
Sbjct: 85 CGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCT-GGCCPASAQAGTGQTDVRTLC 143
Query: 176 NTPGSF-----RCQCPAGYTGPLCENPA---VPCAPSPCRNGG---TCRQSGDLTYD-CA 223
+ G F C C G+ GP C +P +P + P +G C G C
Sbjct: 144 SLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCV 203
Query: 224 CLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPN 283
C PG+ G +C CPG C G CV GV C C ++G C++ + P
Sbjct: 204 CFPGYTGPSC--GWPSCPGD-CQGRGRCVQGV----CVCRAGFSGPDCSQ-----RSCPR 251
Query: 284 ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG 343
C G C G CVC G+TG DDC C G + R + C C G
Sbjct: 252 GCSQRGRC----EGGRCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPG 300
Query: 344 KTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANP-- 401
TG C + C + C +GR C C PG+TG ++C + P
Sbjct: 301 YTGEDCGVRSC--PRGCSQRGRCK----DGR--CVCDPGYTG-------EDCGTRSCPWD 345
Query: 402 CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGF 461
C GRCV+ + C C GYTG C T CR + C D CIC G+
Sbjct: 346 CGEGGRCVDGR----CVCWPGYTGEDCST---RTCPRDCRGRGRCEDG----ECICDTGY 394
Query: 462 TGTYCEVDIDECQSSP--CVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNG 519
+G C V +S P C G C+D C C G++G+ C CR
Sbjct: 395 SGDDCGV-----RSCPGDCNQRGRCEDG----RCVCWPGYTGTDCG---SRACPRDCRGR 442
Query: 520 AKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRC 579
+C + C C G+ G C V C D GRC G C C PGYTG C
Sbjct: 443 GRC----ENGVCVCNAGYSGEDC--GVRSCPGDCRGRGRCESG----RCMCWPGYTGRDC 492
Query: 580 ESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCT-----FGVC 634
++ C CR G+C+D C C G TG +DC S C G+C
Sbjct: 493 GTRA--CPGD-CRGRGRCVD----GRCVCNPGFTG-------EDCGSRRCPGDCRGHGLC 538
Query: 635 RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP 694
DG+ CVC G++G C+ C C G C+DG RC+C G C
Sbjct: 539 EDGV----CVCDAGYSGEDCST--RSCPGG-CRGRGQCLDG----RCVCEDGYSGEDC-- 585
Query: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
C ++ HG+C D C+C G+ CS C S C G C
Sbjct: 586 GVRQCPNDCSQHGVCQDGV----CICWEGYVSEDCSIR----TCPSN-CHGRGRCEEG-- 634
Query: 755 GFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRC-QQDVDE 813
C C PG G C + P C GRC VC C G+ G C Q++
Sbjct: 635 --RCLCDPGYTGPTC--ATRMCPADCRGRGRCVQG-----VCLCHVGYGGEDCGQEEPPA 685
Query: 814 CAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSC 873
A P CGP +C AG C C G+ GP C I C P C G C DG SC
Sbjct: 686 SACPGGCGPRELCR--AG--QCVCVEGFRGPDC--AIQTC-PGDCRGRGECHDG----SC 734
Query: 874 SCLPGFAGPRCARDV 888
C G+AG C +V
Sbjct: 735 VCKDGYAGEDCGEEV 749
Score = 261 bits (668), Expect = 4e-69
Identities = 247/836 (29%), Positives = 310/836 (37%), Gaps = 212/836 (25%)
Query: 175 LNTPGSFRCQCPAGYTGPLCENPA-------------VPCAPSPCRNGGTC---RQSGDL 218
+N P S C CP G P+ + V C GG C Q+G
Sbjct: 77 INLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQC-TGGCCPASAQAGTG 135
Query: 219 TYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDEC 278
D L C H + C C C P W G C++ D
Sbjct: 136 QTDVRTL--------------CSLHGVFDLSRC-------TCSCEPGWGGPTCSDPTD-A 173
Query: 279 QLQPNA-----------CHNGGTCFNTLGGHSCVCVNGWTGESCS--------QNIDDCA 319
++ P++ C++ G C CVC G+TG SC Q C
Sbjct: 174 EIPPSSPPSASGSCPDDCNDQGRCVR----GRCVCFPGYTGPSCGWPSCPGDCQGRGRCV 229
Query: 320 TAVC-----FHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGR 374
VC F G C R +CP G C + C+ GR
Sbjct: 230 QGVCVCRAGFSGPDCSQR------SCPRG----------------CSQRGRCE----GGR 263
Query: 375 AICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNE 434
C C PG+TG C + C G C GRC N + C C GYTG C V
Sbjct: 264 --CVCDPGYTGDDC--GMRSCPRG---CSQRGRCENGR----CVCNPGYTGEDC--GVRS 310
Query: 435 CLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSP--CVNGGVCKDRVNGFS 492
C G C + C D C+C G+TG C +S P C GG C D
Sbjct: 311 CPRG-CSQRGRCKDG----RCVCDPGYTGEDCGT-----RSCPWDCGEGGRCVDG----R 356
Query: 493 CTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPD 552
C C G++G C CR +C D EC C G+ G C V C D
Sbjct: 357 CVCWPGYTGEDCS---TRTCPRDCRGRGRCEDG----ECICDTGYSGDDC--GVRSCPGD 407
Query: 553 PCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 612
GRC DG C C PGYTGT C S+ C + CR G+C + +C C +G
Sbjct: 408 CNQRGRCEDG----RCVCWPGYTGTDCGSRA--C-PRDCRGRGRC----ENGVCVCNAGY 456
Query: 613 TGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSC 672
+G +C V C + G C G C+C PG+TG C C G C
Sbjct: 457 SGEDCGVR--SCPGDCRGRGRCESG----RCMCWPGYTGRDCG---TRACPGDCRGRGRC 507
Query: 673 VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS 732
VDG RC+C PG C S C + HG+C D CVC+ G+SG CS
Sbjct: 508 VDG----RCVCNPGFTGEDC--GSRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCSTR 557
Query: 733 LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQ 792
+C CR G C DG C C G G C + PN C G C+
Sbjct: 558 ----SCPG-GCRGRGQC-LDG---RCVCEDGYSGEDCGVRQ--CPNDCSQHGVCQDG--- 603
Query: 793 LPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDIND 852
VC C +G+ C + C P+ C G C C C GYTGP+C +
Sbjct: 604 --VCICWEGYVSEDC--SIRTC--PSNCHGRGRCE----EGRCLCDPGYTGPTCATRM-- 651
Query: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNP--CGPGTCTDHVASFTC 910
C P C G C GV C C G+ G C ++ + P CGP + + C
Sbjct: 652 C-PADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACPGGCGP---RELCRAGQC 703
Query: 911 TCPPGYGGFHCEQDLPDCS----PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
C G+ G PDC+ P C G C DG SC+C+ GY G C E
Sbjct: 704 VCVEGFRG-------PDCAIQTCPGDCRGRGECHDG----SCVCKDGYAGEDCGEE 748
Score = 236 bits (603), Expect = 1e-61
Identities = 213/737 (28%), Positives = 259/737 (35%), Gaps = 176/737 (23%)
Query: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDG------MGFHCTCPPGVQGRQCEL 771
C CEPGW GP CS + S P A G+C D + C C PG G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW 215
Query: 772 LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAG 831
P P C+ GRC VC C G+ GP C Q + P C G C
Sbjct: 216 --PSCPGDCQGRGRCVQG-----VCVCRAGFSGPDCSQR----SCPRGCSQRGRCEG--- 261
Query: 832 SFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC 891
C C GYTG C + C P C G C++G C C PG+ G C V C
Sbjct: 262 -GRCVCDPGYTGDDCG--MRSC-PRGCSQRGRCENG----RCVCNPGYTGEDCG--VRSC 311
Query: 892 LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCR 951
G C D C C PGY G C C P C GG CVDG C+C
Sbjct: 312 PRGCSQRGRCKDG----RCVCDPGYTGEDC--GTRSC-PWDCGEGGRCVDG----RCVCW 360
Query: 952 PGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQN 1011
PGYTG C P R C G C C C ++G C V C C
Sbjct: 361 PGYTGEDCSTRTCP---RDCRGRGRCEDGE----CICDTGYSGDDCG--VRSCPGD-CNQ 410
Query: 1012 GGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1071
GRC C+C PG++G C R+ P + C+ G+C + CV
Sbjct: 411 RGRCED--GRCVCWPGYTGTDCGSRACP-------------RDCRGRGRC----ENGVCV 451
Query: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC 1131
C G +G C P C+ G C C C PGY G +C C
Sbjct: 452 CNAGYSGEDCGVRSCP---GDCRGRGRCESGR----CMCWPGYTGRDCGT---RACPGDC 501
Query: 1132 QHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCG----PGPPLDSGPRCLHNGTCVDLVG 1187
+ G C+D C C PG G +DCG PG C +G C D V
Sbjct: 502 RGRGRCVD----GRCVCNPGFTG-------EDCGSRRCPGD-------CRGHGLCEDGV- 542
Query: 1188 GFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL 1247
C C GY+G C C G C CL RC+C G+SG C
Sbjct: 543 ---CVCDAGYSGEDCST--RSC-PGGCRGRG--QCLDG-----RCVCEDGYSGEDCGVRQ 589
Query: 1248 SPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQT 1307
P + C G C+ C C + + V+ C CP +
Sbjct: 590 CPND---CSQHGVCQDG---------VCICWEGY-------VSEDCSIRTCPSNCHGRGR 630
Query: 1308 PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCL----HGGS-------------- 1349
RC C PG +GP+C + C CL +GG
Sbjct: 631 CEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPG 690
Query: 1350 -CRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSP 1408
C P L +C C +G+ GP C A Q GD R EC+
Sbjct: 691 GCGPRELCRAGQCVCVEGFRGPDC------------------AIQTCPGDCRGRGECHDG 732
Query: 1409 GC----GWDGGDCSLSV 1421
C G+ G DC V
Sbjct: 733 SCVCKDGYAGEDCGEEV 749
Score = 236 bits (602), Expect = 2e-61
Identities = 205/717 (28%), Positives = 262/717 (36%), Gaps = 171/717 (23%)
Query: 65 CLCPPGWVGERC------------------QLEDPCHS---------------------- 84
C C PGW G C D C+
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW 215
Query: 85 ----GPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDG 140
G C GRG C V C C GF GPDCS C+ RC G
Sbjct: 216 PSCPGDCQGRGRCVQGV--------CVCRAGFSGPDCS--QRSCPRGCSQRGRCEGG--- 262
Query: 141 RFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
C C PGY G C + C G C G C N RC C GYTG C V
Sbjct: 263 --RCVCDPGYTGDDC--GMRSCPRG--CSQRGRCENG----RCVCNPGYTGEDC---GVR 309
Query: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
P C G C+ C C PG+ G++C CP C GG CVDG C
Sbjct: 310 SCPRGCSQRGRCKDG-----RCVCDPGYTGEDC--GTRSCPWD-CGEGGRCVDG----RC 357
Query: 261 QCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCAT 320
C P +TG+ C+ + P C G C + C+C G++G DDC
Sbjct: 358 VCWPGYTGEDCS-----TRTCPRDCRGRGRCED----GECICDTGYSG-------DDCGV 401
Query: 321 AVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCP 380
C R C C G TG C S C D NG +C C
Sbjct: 402 RSCPGDCNQRGRCEDGRCVCWPGYTG------TDCGSRACPRDCRGRGRCENG--VCVCN 453
Query: 381 PGFTGGACDQDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG 438
G++G ++C + + P C GRC + + C C GYTG C T G
Sbjct: 454 AGYSG-------EDCGVRSCPGDCRGRGRCESGR----CMCWPGYTGRDCGT---RACPG 499
Query: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG 498
CR + C+D C+C GFTG C C C G+C+D V C C +G
Sbjct: 500 DCRGRGRCVDG----RCVCNPGFTGEDC--GSRRCPGD-CRGHGLCEDGV----CVCDAG 548
Query: 499 FSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR 558
+SG C CR +C+D C C +G+ G C V C D HG
Sbjct: 549 YSGEDCS---TRSCPGGCRGRGQCLDG----RCVCEDGYSGEDC--GVRQCPNDCSQHGV 599
Query: 559 CVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCE 618
C DG+ C C GY C + C S C G+C ++ C C G TG C
Sbjct: 600 CQDGV----CICWEGYVSEDC--SIRTCPSN-CHGRGRC----EEGRCLCDPGYTGPTCA 648
Query: 619 VNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP--CGEGGSCVDGE 676
+ C ++ G C G+ C+C G+ G C E ++ P CG C G+
Sbjct: 649 TRM--CPADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQ 702
Query: 677 NGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSL 733
C+C G P C C + G C+D CVC+ G++G C + +
Sbjct: 703 ----CVCVEGFRGPDC--AIQTCPGDCRGRGECHDG----SCVCKDGYAGEDCGEEV 749
Score = 191 bits (486), Expect = 5e-48
Identities = 214/766 (27%), Positives = 255/766 (33%), Gaps = 195/766 (25%)
Query: 798 CPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDP-- 855
CP Q Q DV C HG+ +C+C G+ GP+C + P
Sbjct: 126 CPASAQAGTGQTDVRTL-----CSLHGVFD--LSRCTCSCEPGWGGPTCSDPTDAEIPPS 178
Query: 856 NPCLNGGSCQDGVGSFS------CSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFT 909
+P GSC D C C PG+ GP C C + G G C V
Sbjct: 179 SPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWP--SCPGDCQGRGRCVQGV---- 232
Query: 910 CTCPPGYGGFHCEQDLPDCSPSSCFNG----GTCVDGVNSFSCLCRPGYTGAHCQHEADP 965
C C G+ G PDCS SC G G C G C+C PGYTG C + P
Sbjct: 233 CVCRAGFSG-------PDCSQRSCPRGCSQRGRCEGG----RCVCDPGYTGDDCGMRSCP 281
Query: 966 CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCP 1025
R C G C RC C +TG C V C R C GRC C+C
Sbjct: 282 ---RGCSQRGRCENG----RCVCNPGYTGEDCG--VRSCPRG-CSQRGRCKD--GRCVCD 329
Query: 1026 PGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV 1085
PG++G C RS P C GG+CVD CVC G TG C
Sbjct: 330 PGYTGEDCGTRSCPWD-------------CGEGGRCVDGR----CVCWPGYTGEDCSTRT 372
Query: 1086 DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1145
P + C+ G C C C GY+GD+C V C C G C D
Sbjct: 373 CP---RDCRGRGRCEDGE----CICDTGYSGDDC--GVRSCPGD-CNQRGRCED----GR 418
Query: 1146 CSCPPGTLGVLCEINEDDCGPGP-PLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG----- 1199
C C PG G DCG P D C G C + V C C GY+G
Sbjct: 419 CVCWPGYTGT-------DCGSRACPRD----CRGRGRCENGV----CVCNAGYSGEDCGV 463
Query: 1200 LRCEADIN---ECRSGACHA--------AHTRDCLQDPGG-----GFRCLCHAGFSGPRC 1243
C D C SG C TR C D G RC+C+ GF+G C
Sbjct: 464 RSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDC 523
Query: 1244 QTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVP 1303
+ P + C+ G C C C + G C CP G
Sbjct: 524 GSRRCPGD---CRGHGLCEDG---------VCVCDAGYSG-------EDCSTRSCPGGCR 564
Query: 1304 CQQTPRGPRCACPPGLSGPSC--RSFPGSPP--------------GASNASCAAAPC--- 1344
+ RC C G SG C R P G + C+ C
Sbjct: 565 GRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSN 624
Query: 1345 LHG-GSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAAC--QAKRGDQRC 1401
HG G C RC C G+TGP C + RC + C G + C
Sbjct: 625 CHGRGRCEEG------RCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDC 678
Query: 1402 DRECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAG 1461
+E P GG C P C A QC C P C
Sbjct: 679 GQE-EPPASACPGG-CG-----PRELCRAGQCV-------CVEGFRGPDCAIQTCPGDCR 724
Query: 1462 GRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPAL 1507
GR G C G + G+ G DC EVP +
Sbjct: 725 GR------------------GECHDGSCVCKDGYAGEDCGEEVPTI 752
Score = 180 bits (457), Expect = 1e-44
Identities = 151/529 (28%), Positives = 197/529 (37%), Gaps = 125/529 (23%)
Query: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLED-------------------PCHSG---- 85
C+ GRC ++ C+C PG+ GE C P ++G
Sbjct: 315 CSQRGRC-----KDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCS 369
Query: 86 ------PCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPD 139
C GRG C+ C C G+ G DC + C RC D
Sbjct: 370 TRTCPRDCRGRGRCEDG--------ECICDTGYSGDDCGVRS--CPGDCNQRGRCE---D 416
Query: 140 GRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
GR C C PGY G C S CR G C N C C AGY+G C V
Sbjct: 417 GR--CVCWPGYTGTDCGSRA----CPRDCRGRGRCENGV----CVCNAGYSGEDC---GV 463
Query: 200 PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYN 259
P CR G C +SG C C PG+ G++C CPG C G CVDG
Sbjct: 464 RSCPGDCRGRGRC-ESG----RCMCWPGYTGRDCGTRA--CPGD-CRGRGRCVDG----R 511
Query: 260 CQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
C C P +TG+ C + P C G C + + CVC G++GE DC+
Sbjct: 512 CVCNPGFTGEDCGS-----RRCPGDCRGHGLCEDGV----CVCDAGYSGE-------DCS 555
Query: 320 TAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC 379
T C G + C C G +G C + N C + +C +C C
Sbjct: 556 TRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQC--PNDCSQHGVCQD------GVCIC 607
Query: 380 PPGFTGGACDQDVDECSIGANP--CEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS 437
G+ ++CSI P C GRC + C C GYTGP C T
Sbjct: 608 WEGYVS-------EDCSIRTCPSNCHGRGRCEEGR----CLCDPGYTGPTCAT---RMCP 653
Query: 438 GPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPS 497
CR + C+ Q C+C G+ G C +E +S C G ++ C C
Sbjct: 654 ADCRGRGRCV----QGVCLCHVGYGGEDC--GQEEPPASACPGGCGPRELCRAGQCVCVE 707
Query: 498 GFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNV 546
GF G C + + CR +C D C C +G+ G C V
Sbjct: 708 GFRGPDCAI---QTCPGDCRGRGECHDG----SCVCKDGYAGEDCGEEV 749
Score = 76.3 bits (186), Expect = 3e-13
Identities = 57/203 (28%), Positives = 75/203 (36%), Gaps = 47/203 (23%)
Query: 49 CANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRC 108
C+ G C ++ C+C G+V E C + C S C GRG C+ C C
Sbjct: 594 CSQHGVC-----QDGVCICWEGYVSEDCSIRT-CPSN-CHGRGRCEEG--------RCLC 638
Query: 109 PRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDE------- 161
G+ GP C+ + C RC G +C C GY G C +
Sbjct: 639 DPGYTGPTCATR--MCPADCRGRGRCVQG-----VCLCHVGYGGEDCGQEEPPASACPGG 691
Query: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYD 221
C E CR G +C C G+ GP C A+ P CR G C
Sbjct: 692 CGPRELCRAG----------QCVCVEGFRGPDC---AIQTCPGDCRGRGECHDGS----- 733
Query: 222 CACLPGFEGQNCEVNVDDCPGHR 244
C C G+ G++C V G R
Sbjct: 734 CVCKDGYAGEDCGEEVPTIEGMR 756
Score = 64.7 bits (156), Expect = 1e-09
Identities = 43/133 (32%), Positives = 53/133 (39%), Gaps = 26/133 (19%)
Query: 33 LAGPGAAAPPC---LDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHS---GP 86
L PG P C + + C GRC Q CLC G+ GE C E+P S G
Sbjct: 637 LCDPGYTGPTCATRMCPADCRGRGRCVQ-----GVCLCHVGYGGEDCGQEEPPASACPGG 691
Query: 87 CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSC 146
C R +C++ C C GFRGPDC++ C C G C C
Sbjct: 692 CGPRELCRAG--------QCVCVEGFRGPDCAI--QTCPGDCRGRGECHDGS-----CVC 736
Query: 147 PPGYQGRSCRSDV 159
GY G C +V
Sbjct: 737 KDGYAGEDCGEEV 749
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 265 bits (678), Expect = 3e-70
Identities = 153/452 (33%), Positives = 223/452 (49%), Gaps = 35/452 (7%)
Query: 140 GRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQ-CPAGYTGPLCENPA 198
GR +CP G + CR+G + + G C+ CP+G +
Sbjct: 996 GRMCVNCPLGTYYNLEHFTCESCRIG-------SYQDEEGQLECKLCPSGMYTEYIHSRN 1048
Query: 199 VPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDG-VNT 257
+ + C+ G T SG T + L ++ + + CP N T G VN
Sbjct: 1049 ISDCKAQCKQG-TYSYSGLETCESCPLGTYQPKFGSRSCLSCPE----NTSTVKRGAVNI 1103
Query: 258 YNCQCP-PEWTGQFCTEDVDECQLQPNACH--NGGTCFNTLGGHSCVCVN--GWTGESCS 312
C P PE G+F + C P + N G F C+ G T + S
Sbjct: 1104 SACGVPCPE--GKFSRSGLMPCHPCPRDYYQPNAGKAF-------CLACPFYGTTPFAGS 1154
Query: 313 QNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVN 372
++I +C++ A V + + + C NPCH C
Sbjct: 1155 RSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQL--- 1211
Query: 373 GRA-ICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETD 431
GR +C CP G+TG C+ D+DECS PC + G C + G F+C+C GYTG RCE +
Sbjct: 1212 GRGYVCLCPLGYTGLKCETDIDECS--PLPCLNNGVCKDLVGEFICECPSGYTGQRCEEN 1269
Query: 432 VNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGF 491
+NEC S PC N+ C+D + + C C+ GF G +CE +++ECQS+PC+N VC+D+V GF
Sbjct: 1270 INECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGF 1329
Query: 492 SCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP 551
C CP GF G+ C +VDEC S PC+NGA C D + + C CA GF G+ C+ N+++C
Sbjct: 1330 LCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQS 1389
Query: 552 DPC-HHGRCVDGIASFSCACAPGYTGTRCESQ 582
+PC + CVD + S+SC C PG++G RCE++
Sbjct: 1390 NPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 264 bits (674), Expect = 9e-70
Identities = 175/515 (33%), Positives = 230/515 (44%), Gaps = 100/515 (19%)
Query: 162 CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPL----CENPAVPCAPSPCRNGGTCRQSGD 217
CR G R G C+N CP G L CE+ CR G + G
Sbjct: 988 CRPGSVLR-GRMCVN--------CPLGTYYNLEHFTCES---------CRIGSYQDEEGQ 1029
Query: 218 LTYDCACLPGFEGQNCEV----NVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTE 273
L +C P G E N+ DC C G +Y+ E
Sbjct: 1030 L--ECKLCPS--GMYTEYIHSRNISDCKAQ-------CKQGTYSYSG-----------LE 1067
Query: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV 333
+ C L GT G SC+ SC +N T+ GA +
Sbjct: 1068 TCESCPL--------GTYQPKFGSRSCL--------SCPEN-----TSTVKRGAV---NI 1103
Query: 334 ASFYCACPMGK---TGLL-CHLDDACVSNPCHEDAICDTNPVNGRAICTCPP--GFTGGA 387
++ CP GK +GL+ CH PC D P G+A C P G T A
Sbjct: 1104 SACGVPCPEGKFSRSGLMPCH--------PCPRDYY---QPNAGKAFCLACPFYGTTPFA 1152
Query: 388 CDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETD---VNECLSGPCRNQA 444
+ + ECS ++ V S G+ R E +EC PC N
Sbjct: 1153 GSRSITECSSFSSTFSAAEESVVPPASL------GHIKKRHEISSQVFHECFFNPCHNSG 1206
Query: 445 TCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTC 504
TC + C+C G+TG CE DIDEC PC+N GVCKD V F C CPSG++G C
Sbjct: 1207 TCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRC 1266
Query: 505 QLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPC-HHGRCVDGI 563
+ +++EC+S+PC N CVD GY C C +GF G C+ V++C +PC ++ C D +
Sbjct: 1267 EENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQV 1326
Query: 564 ASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD 623
F C C PG+ GTRC VDEC SQPC++G C D + + C C +G TG +CE+NI++
Sbjct: 1327 GGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINE 1386
Query: 624 CASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVE 657
C SNPC C D +N Y C CQPGF+G C E
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 214 bits (544), Expect = 1e-54
Identities = 95/226 (42%), Positives = 127/226 (56%), Gaps = 5/226 (2%)
Query: 548 DCSPDPCHH-GRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLC 606
+C +PCH+ G C + C C GYTG +CE+ +DEC PC + G C DLV +++C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 607 RCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSP 665
CPSG TG CE NI++C+S+PC G+C DG+ Y C C GF G C E+NEC S+P
Sbjct: 1256 ECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP 1315
Query: 666 CGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGW 724
C C D GF C CPPG L C C +PC +G C D FRC+C G+
Sbjct: 1316 CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGF 1375
Query: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCE 770
+G C ++ + C+S PCR TC + + C C PG G++CE
Sbjct: 1376 TGSHCELNI--NECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 203 bits (516), Expect = 2e-51
Identities = 90/233 (38%), Positives = 127/233 (54%), Gaps = 15/233 (6%)
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
C G C + C+CP G TG CE ++D C PC + G C+ +G ++CEC GY
Sbjct: 1202 CHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGY 1261
Query: 1115 NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
G CE++++EC+S PC + G C+D VA Y C+C G +G+ CE ++C P
Sbjct: 1262 TGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP------ 1315
Query: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLC 1234
CL+N C D VGGF C CPPG+ G RC +++EC S C T +D FRCLC
Sbjct: 1316 -CLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGAT---CKDGANSFRCLC 1371
Query: 1235 HAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE 1287
AGF+G C+ ++ C+S PC++ C +++C C F G RCE
Sbjct: 1372 AAGFTGSHCELNINECQSNPCRNQATCVDELN-----SYSCKCQPGFSGKRCE 1419
Score = 200 bits (509), Expect = 1e-50
Identities = 134/421 (31%), Positives = 177/421 (42%), Gaps = 53/421 (12%)
Query: 702 EPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG-------TCSSDGM 754
E C G D G C P S C++Q C+ G TC S +
Sbjct: 1016 ESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSYSGLETCESCPL 1074
Query: 755 GFH---------CTCPPGVQG--RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQ 803
G + +CP R +S C PC G S G +P CP+ +
Sbjct: 1075 GTYQPKFGSRSCLSCPENTSTVKRGAVNISACGV-PCPEGKFSRS--GLMPCHPCPRDYY 1131
Query: 804 GPRCQQDVDECA---GPAP-CGPHGI--CTNLAGSFSCTCHGGYTGPSC----------D 847
P + G P G I C++ + +FS S
Sbjct: 1132 QPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISS 1191
Query: 848 QDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVA 906
Q ++C NPC N G+CQ + C C G+ G +C D+DEC PC G C D V
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVG 1251
Query: 907 SFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPC 966
F C CP GY G CE+++ +CS S C N G CVDGV + C C G+ G HC+ E + C
Sbjct: 1252 EFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNEC 1311
Query: 967 LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGA---YCL 1023
S PCL+ VC GF C C F G +C VD C QPC+NG C + GA CL
Sbjct: 1312 QSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATC-KDGANSFRCL 1370
Query: 1024 CPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQ 1083
C G++G C++ C+ C+ CVDE +S+ C C G +G CE
Sbjct: 1371 CAAGFTGSHCELNINECQ----------SNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Query: 1084 E 1084
E
Sbjct: 1421 E 1421
Score = 200 bits (508), Expect = 2e-50
Identities = 96/239 (40%), Positives = 121/239 (50%), Gaps = 15/239 (6%)
Query: 1088 CLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
C PC + GTC+ GY+C C GY G CE D+DEC+ PC + G C DLV ++C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICE 1256
Query: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN 1207
CP G G CE N ++C P CL+ G CVD V G+RCTC G+ GL CE ++N
Sbjct: 1257 CPSGYTGQRCEENINECSSSP-------CLNKGICVDGVAGYRCTCVKGFVGLHCETEVN 1309
Query: 1208 ECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGP 1267
EC+S C + C +D GGF C C GF G RC + C SQPC++G C+
Sbjct: 1310 ECQSNPC--LNNAVC-EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK----- 1361
Query: 1268 GGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRS 1326
G +F C CA F G CE C+ C C C C PG SG C +
Sbjct: 1362 DGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCET 1420
Score = 198 bits (504), Expect = 4e-50
Identities = 92/232 (39%), Positives = 125/232 (53%), Gaps = 5/232 (2%)
Query: 123 CLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFR 182
C +PC + C G ++C CP GY G C +D+DEC PC + G C + G F
Sbjct: 1197 CFFNPCHNSGTCQQLGRG-YVCLCPLGYTGLKCETDIDECSP-LPCLNNGVCKDLVGEFI 1254
Query: 183 CQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPG 242
C+CP+GYTG CE C+ SPC N G C G Y C C+ GF G +CE V++C
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGIC-VDGVAGYRCTCVKGFVGLHCETEVNECQS 1313
Query: 243 HRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVC 302
+ CLN C D V + C+CPP + G C ++VDEC QP C NG TC + C+C
Sbjct: 1314 NPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP--CKNGATCKDGANSFRCLC 1371
Query: 303 VNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDA 354
G+TG C NI++C + C + ATC D + S+ C C G +G C + +
Sbjct: 1372 AAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 197 bits (502), Expect = 8e-50
Identities = 128/434 (29%), Positives = 189/434 (43%), Gaps = 18/434 (4%)
Query: 456 ICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCT-CPSG-FSGSTCQLDVDECAS 513
+C+ GTY ++ C+S G +D C CPSG ++ ++ +C +
Sbjct: 998 MCVNCPLGTYYNLEHFTCESCRI---GSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKA 1054
Query: 514 TPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPG 573
C+ G + E ++ R+ C P + G + S P
Sbjct: 1055 Q-CKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSC---PENTSTVKRGAVNISACGVPC 1110
Query: 574 YTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPS-GTTGVNCEVNIDDCASNPCTFG 632
G S + C PC + + CP GTT +I +C+S TF
Sbjct: 1111 PEGKFSRSGLMPCH--PCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFS 1168
Query: 633 VCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLC 692
+ + + + + +EC +PC G+C G+ CLCP G C
Sbjct: 1169 AAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKC 1228
Query: 693 LPPSHPCAHEPC-SHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSS 751
C+ PC ++G+C D G F C C G++G RC +++ + C S PC G C
Sbjct: 1229 ETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENI--NECSSSPCLNKGICVD 1286
Query: 752 DGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQD 810
G+ CTC G G CE ++ C NPC + CE G +C CP G+ G RC ++
Sbjct: 1287 GVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGF-LCKCPPGFLGTRCGKN 1345
Query: 811 VDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGS 870
VDEC PC C + A SF C C G+TG C+ +IN+C NPC N +C D + S
Sbjct: 1346 VDECLS-QPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNS 1404
Query: 871 FSCSCLPGFAGPRC 884
+SC C PGF+G RC
Sbjct: 1405 YSCKCQPGFSGKRC 1418
Score = 191 bits (486), Expect = 5e-48
Identities = 135/463 (29%), Positives = 195/463 (42%), Gaps = 46/463 (9%)
Query: 760 CPPG--VQGRQCELLSPCTPNPCEHGGRCESA--------PGQLPVCSCPQGWQGPRCQ- 808
C PG ++GR C T EH CES GQL CP G
Sbjct: 988 CRPGSVLRGRMCVNCPLGTYYNLEHF-TCESCRIGSYQDEEGQLECKLCPSGMYTEYIHS 1046
Query: 809 QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV 868
+++ +C G + + L SC G Y + C N + + G
Sbjct: 1047 RNISDCKAQCKQGTYSY-SGLETCESCPL-GTYQPKFGSRSCLSCPENT----STVKRGA 1100
Query: 869 GSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGG--FHCEQDLP 926
+ S +P G + C +PC + C P YG F + +
Sbjct: 1101 VNISACGVPCPEGKFSRSGLMPC--HPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSIT 1158
Query: 927 DCSP-SSCFNGGT-CVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
+CS SS F+ V S + + + HE C PC + G C G+
Sbjct: 1159 ECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHE---CFFNPCHNSGTCQQLGRGY 1215
Query: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ-TGAY-CLCPPGWSGRLCDIRSLPCRE 1042
C C +TG +C+T +D CS PC N G C G + C CP G++G+ C+ C
Sbjct: 1216 VCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSS 1275
Query: 1043 AAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGY 1102
+ C G CVD + + C C +G G HCE EV+ C + PC + C
Sbjct: 1276 SP----------CLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQ 1325
Query: 1103 MGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINED 1162
+GG++C+C PG+ G C +VDEC SQPC++G +C D + C C G G CE+N +
Sbjct: 1326 VGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNIN 1385
Query: 1163 DCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEAD 1205
+C P C + TCVD + + C C PG++G RCE +
Sbjct: 1386 ECQSNP-------CRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 186 bits (471), Expect = 3e-46
Identities = 131/460 (28%), Positives = 180/460 (39%), Gaps = 76/460 (16%)
Query: 732 SLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL--LSPCTPNPCEHGG----- 784
+L CES CR G +G CP G+ +S C C+ G
Sbjct: 1009 NLEHFTCES--CRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ-CKQGTYSYSG 1065
Query: 785 --RCESAP--------GQLPVCSCPQGWQG-PRCQQDVDECAGPAPCGPHGICTNLAGSF 833
CES P G SCP+ R ++ C P P G + S
Sbjct: 1066 LETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEG------KFSRSG 1119
Query: 834 SCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLP-----GFAGPRCARDV 888
CH C +D Q G C P FAG +R +
Sbjct: 1120 LMPCH------PCPRDYY-------------QPNAGKAFCLACPFYGTTPFAG---SRSI 1157
Query: 889 DECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP-----DCSPSSCFNGGTCVDGV 943
EC S + T A + P G ++ +C + C N GTC
Sbjct: 1158 TECSSF-----SSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLG 1212
Query: 944 NSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDW 1003
+ CLC GYTG C+ + D C PCL+ GVC F C C +TG +C+ ++
Sbjct: 1213 RGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINE 1272
Query: 1004 CSRQPCQNGGRCVQ--TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
CS PC N G CV G C C G+ G C+ C+ C C
Sbjct: 1273 CSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNP----------CLNNAVC 1322
Query: 1062 VDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED 1121
D+ C CP G G+ C + VD CL+QPC++G TC+ + C C G+ G +CE
Sbjct: 1323 EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCEL 1382
Query: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINE 1161
+++EC S PC++ +C+D + Y C C PG G CE +
Sbjct: 1383 NINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQ 1422
Score = 185 bits (469), Expect = 5e-46
Identities = 87/227 (38%), Positives = 124/227 (54%), Gaps = 10/227 (4%)
Query: 47 SPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFS 105
+PC N G C QL R CLCP G+ G +C+ + D C PC GVC+ V F
Sbjct: 1200 NPCHNSGTCQQL-GRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLV----GEFI 1254
Query: 106 CRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV 164
C CP G+ G C + C SSPC + C G G + C+C G+ G C ++V+EC+
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAG-YRCTCVKGFVGLHCETEVNECQ- 1312
Query: 165 GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 224
PC + C + G F C+CP G+ G C C PC+NG TC+ G ++ C C
Sbjct: 1313 SNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCK-DGANSFRCLC 1371
Query: 225 LPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFC 271
GF G +CE+N+++C + C N TCVD +N+Y+C+C P ++G+ C
Sbjct: 1372 AAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRC 1418
Score = 170 bits (431), Expect = 1e-41
Identities = 89/249 (35%), Positives = 114/249 (45%), Gaps = 25/249 (10%)
Query: 1125 ECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD 1184
EC PC + G+C L Y+C CP G G+ CE + D+C P P CL+NG C D
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP-------CLNNGVCKD 1248
Query: 1185 LVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQ 1244
LVG F C CP GYTG RCE +INEC S C + D G+RC C GF G C+
Sbjct: 1249 LVGEFICECPSGYTGQRCEENINECSSSPC---LNKGICVDGVAGYRCTCVKGFVGLHCE 1305
Query: 1245 TVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPC 1304
T ++ C+S PC + C G F C C F G RC + C C G C
Sbjct: 1306 TEVNECQSNPCLNNAVCEDQVG-----GFLCKCPPGFLGTRCGKNVDECLSQPCKNGATC 1360
Query: 1305 QQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACA 1364
+ RC C G +G C + C + PC + +C + C C
Sbjct: 1361 KDGANSFRCLCAAGFTGSHCE--------LNINECQSNPCRNQATC--VDELNSYSCKCQ 1410
Query: 1365 QGWTGPRCE 1373
G++G RCE
Sbjct: 1411 PGFSGKRCE 1419
Score = 162 bits (411), Expect = 3e-39
Identities = 81/189 (42%), Positives = 104/189 (55%), Gaps = 10/189 (5%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFSC 106
PC N G C L E C CP G+ G+RC+ + C S PC +G+C V G A + C
Sbjct: 1239 PCLNNGVCKDLVG-EFICECPSGYTGQRCEENINECSSSPCLNKGIC----VDGVAGYRC 1293
Query: 107 RCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG 165
C +GF G C + C S+PC + A C G FLC CPPG+ G C +VDEC +
Sbjct: 1294 TCVKGFVGLHCETEVNECQSNPCLNNAVCE-DQVGGFLCKCPPGFLGTRCGKNVDEC-LS 1351
Query: 166 EPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL 225
+PC++G TC + SFRC C AG+TG CE C +PCRN TC + +Y C C
Sbjct: 1352 QPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELN-SYSCKCQ 1410
Query: 226 PGFEGQNCE 234
PGF G+ CE
Sbjct: 1411 PGFSGKRCE 1419
Score = 113 bits (283), Expect = 2e-24
Identities = 58/151 (38%), Positives = 78/151 (51%), Gaps = 9/151 (5%)
Query: 47 SPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFS 105
SPC N G C + C C G+VG C+ E + C S PC VC+ V F
Sbjct: 1276 SPCLNKGICVDGVAGYR-CTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQV----GGFL 1330
Query: 106 CRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRV 164
C+CP GF G C D CLS PC +GA C G + F C C G+ G C +++EC+
Sbjct: 1331 CKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANS-FRCLCAAGFTGSHCELNINECQ- 1388
Query: 165 GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE 195
PCR+ TC++ S+ C+C G++G CE
Sbjct: 1389 SNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 80.5 bits (197), Expect = 2e-14
Identities = 44/109 (40%), Positives = 57/109 (52%), Gaps = 18/109 (16%)
Query: 205 PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPP 264
PC+NGG C++ C+C G+ G+ CE + P CLNGG CV Y C CPP
Sbjct: 3475 PCQNGGICQRPNA----CSCPEGWMGRLCEEPICILP---CLNGGRCVA---PYQCDCPP 3524
Query: 265 EWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQ 313
WTG C V CQ + C NGG C + C C++ WTG +CS+
Sbjct: 3525 GWTGSRCHTAV--CQ---SPCLNGGKCVRP---NRCHCLSSWTGHNCSR 3565
Score = 78.6 bits (192), Expect = 7e-14
Identities = 53/140 (37%), Positives = 64/140 (45%), Gaps = 34/140 (24%)
Query: 985 RCTCLESFTG---PQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCD--IRSLP 1039
R CLE+ T P C+ + R PCQNGG C + A C CP GW GRLC+ I LP
Sbjct: 3453 RSVCLENGTWTSPPICRAVC----RFPCQNGGICQRPNA-CSCPEGWMGRLCEEPICILP 3507
Query: 1040 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC 1099
C GG+CV + + C CP G TGS C V PC +GG C
Sbjct: 3508 CLN---------------GGRCV---APYQCDCPPGWTGSRCHTAV---CQSPCLNGGKC 3546
Query: 1100 RGYMGGYMCECLPGYNGDNC 1119
+ C CL + G NC
Sbjct: 3547 ---VRPNRCHCLSSWTGHNC 3563
Score = 77.8 bits (190), Expect = 1e-13
Identities = 109/437 (24%), Positives = 160/437 (36%), Gaps = 83/437 (18%)
Query: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHN--GGTCFNTLGGHSCV 301
RCL G T +T+ CQ W + + +C L N H G F+ S
Sbjct: 3147 RCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVS 3206
Query: 302 CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMG-KTGLLC---HLDDACVS 357
C G+T E NI C + + + C P + G + + ++ +
Sbjct: 3207 CAEGYTFEGV--NISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTII 3264
Query: 358 NPC--------HEDAICDTNPV--NGRAICT-----CPPGFTGGACDQDVDECSIGANPC 402
C + + +C N G AIC P F G D ++ + G N
Sbjct: 3265 YQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKAD--IENRTTGPNVV 3322
Query: 403 EHLGRCVNTQGSFLCQCGRGYTG----PRCETD--------------------VNECLSG 438
R + +G C T P C+ + V++ +S
Sbjct: 3323 YSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSI 3382
Query: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCK-------DRVNGF 491
CR + L G TC +T T + + C V + + D + +
Sbjct: 3383 KCR-EGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMIT-Y 3440
Query: 492 SCTCP---SGFSGSTCQ-----LDVDECAST---PCRNGAKCVDQPDGYECRCAEGFEGT 540
SC GF S C C + PC+NG C +P+ C C EG+ G
Sbjct: 3441 SCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGIC-QRPNA--CSCPEGWMGR 3497
Query: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
LC+ + C + GRCV A + C C PG+TG+RC + V C+S PC +GGKC
Sbjct: 3498 LCEEPI--CILPCLNGGRCV---APYQCDCPPGWTGSRCHTAV--CQS-PCLNGGKC--- 3546
Query: 601 VDKYLCRCPSGTTGVNC 617
V C C S TG NC
Sbjct: 3547 VRPNRCHCLSSWTGHNC 3563
Score = 77.0 bits (188), Expect = 2e-13
Identities = 43/106 (40%), Positives = 49/106 (46%), Gaps = 16/106 (15%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP 226
PC++GG C P + C CP G+ G LCE P PC NGG C Y C C P
Sbjct: 3475 PCQNGGIC-QRPNA--CSCPEGWMGRLCEE---PICILPCLNGGRC----VAPYQCDCPP 3524
Query: 227 GFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCT 272
G+ G C V P CLNGG C V C C WTG C+
Sbjct: 3525 GWTGSRCHTAVCQSP---CLNGGKC---VRPNRCHCLSSWTGHNCS 3564
Score = 70.9 bits (172), Expect = 1e-11
Identities = 51/141 (36%), Positives = 63/141 (44%), Gaps = 23/141 (16%)
Query: 710 YDAPGGFRCVC-EPG-WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGR 767
Y G R VC E G W+ P +++ R PC+ GG C C+CP G GR
Sbjct: 3446 YMLEGFLRSVCLENGTWTSPPICRAVCRF-----PCQNGGICQRPNA---CSCPEGWMGR 3497
Query: 768 QCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT 827
CE P PC +GGRC AP Q C CP GW G RC V + +PC G C
Sbjct: 3498 LCE--EPICILPCLNGGRC-VAPYQ---CDCPPGWTGSRCHTAVCQ----SPCLNGGKCV 3547
Query: 828 NLAGSFSCTCHGGYTGPSCDQ 848
C C +TG +C +
Sbjct: 3548 R---PNRCHCLSSWTGHNCSR 3565
Score = 68.9 bits (167), Expect = 5e-11
Identities = 39/108 (36%), Positives = 52/108 (48%), Gaps = 17/108 (15%)
Query: 779 PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCH 838
PC++GG C+ CSCP+GW G C++ + C PC G C + C C
Sbjct: 3475 PCQNGGICQRPNA----CSCPEGWMGRLCEEPI--CI--LPCLNGGRC---VAPYQCDCP 3523
Query: 839 GGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
G+TG C + C +PCLNGG C V C CL + G C+R
Sbjct: 3524 PGWTGSRCHTAV--CQ-SPCLNGGKC---VRPNRCHCLSSWTGHNCSR 3565
Score = 68.9 bits (167), Expect = 5e-11
Identities = 39/107 (36%), Positives = 51/107 (47%), Gaps = 18/107 (16%)
Query: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCP 186
PC +G C P+ CSCP G+ GR C + C + PC +GG C+ ++C CP
Sbjct: 3475 PCQNGGICQ-RPNA---CSCPEGWMGRLCEEPI--CIL--PCLNGGRCV---APYQCDCP 3523
Query: 187 AGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNC 233
G+TG C SPC NGG C + C CL + G NC
Sbjct: 3524 PGWTGSRCHTAV---CQSPCLNGGKCVRPN----RCHCLSSWTGHNC 3563
Score = 67.0 bits (162), Expect = 2e-10
Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 933 CFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF 992
C NGG C +C C G+ G C+ +P PCL+GG C A ++C C +
Sbjct: 3476 CQNGGICQ---RPNACSCPEGWMGRLCE---EPICILPCLNGGRCVAP---YQCDCPPGW 3526
Query: 993 TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLC 1033
TG +C T V + PC NGG+CV+ C C W+G C
Sbjct: 3527 TGSRCHTAV---CQSPCLNGGKCVRPNR-CHCLSSWTGHNC 3563
Score = 64.7 bits (156), Expect = 1e-09
Identities = 39/108 (36%), Positives = 48/108 (44%), Gaps = 19/108 (17%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCR 107
PC NGG C R AC CP GW+G C E+P PC G C A + C
Sbjct: 3475 PCQNGGIC----QRPNACSCPEGWMGRLC--EEPICILPCLNGGRC-------VAPYQCD 3521
Query: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSC 155
CP G+ G C SPC +G +C V P+ C C + G +C
Sbjct: 3522 CPPGWTGSRCH--TAVCQSPCLNGGKC-VRPN---RCHCLSSWTGHNC 3563
Score = 63.2 bits (152), Expect = 3e-09
Identities = 40/106 (37%), Positives = 50/106 (47%), Gaps = 15/106 (14%)
Query: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG 498
PC+N C C C G+ G CE I C PC+NGG C V + C CP G
Sbjct: 3475 PCQNGGICQR---PNACSCPEGWMGRLCEEPI--C-ILPCLNGGRC---VAPYQCDCPPG 3525
Query: 499 FSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDR 544
++GS C V +PC NG KCV +P+ C C + G C R
Sbjct: 3526 WTGSRCHTAV---CQSPCLNGGKCV-RPN--RCHCLSSWTGHNCSR 3565
Score = 62.4 bits (150), Expect = 5e-09
Identities = 34/84 (40%), Positives = 43/84 (51%), Gaps = 12/84 (14%)
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
CQ GG C ++ C CPEG G CE+ P PC +GG C + Y C+C PG+
Sbjct: 3476 CQNGGICQRPNA---CSCPEGWMGRLCEE---PICILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 1115 NGDNCEDDVDECASQPCQHGGSCI 1138
G C V C S PC +GG C+
Sbjct: 3527 TGSRCHTAV--CQS-PCLNGGKCV 3547
Score = 61.2 bits (147), Expect = 1e-08
Identities = 37/106 (34%), Positives = 47/106 (44%), Gaps = 14/106 (13%)
Query: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGY 916
PC NGG CQ +CSC G+ G C + C+ G C VA + C CPPG+
Sbjct: 3475 PCQNGGICQR---PNACSCPEGWMGRLCEEPI--CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 917 GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE 962
G C + S C NGG C V C C +TG +C +
Sbjct: 3527 TGSRCHTAV---CQSPCLNGGKC---VRPNRCHCLSSWTGHNCSRK 3566
Score = 60.1 bits (144), Expect = 2e-08
Identities = 58/218 (26%), Positives = 78/218 (35%), Gaps = 34/218 (15%)
Query: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHG 1347
+V C C CQQ RG C CP G +G C + C+ PCL+
Sbjct: 1192 QVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCET--------DIDECSPLPCLNN 1243
Query: 1348 GSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNS 1407
G C+ L F C C G+TG RCE E S P + C RC C
Sbjct: 1244 GVCK--DLVGEFICECPSGYTGQRCE--ENINECSSSPCLNKGICVDGVAGYRC--TCVK 1297
Query: 1408 PGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTC 1467
G+ G C V +C++ C NN+ C+ C C G C
Sbjct: 1298 ---GFVGLHCETEV----NECQSNPC---LNNAVCEDQVGGFLC-----KCPPGFLGTRC 1342
Query: 1468 NPVYEKYCADHFADG-RCDQGCNTEEC----GWDGLDC 1500
++ + +G C G N+ C G+ G C
Sbjct: 1343 GKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHC 1380
Score = 60.1 bits (144), Expect = 2e-08
Identities = 49/164 (29%), Positives = 61/164 (37%), Gaps = 70/164 (42%)
Query: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGF 1189
PCQ+GG C A CSCP G +G LCE P+ P CL+ G CV +
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCE---------EPICILP-CLNGGRCV---APY 3518
Query: 1190 RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP 1249
+C CPPG+TG RC HT C
Sbjct: 3519 QCDCPPGWTGSRC---------------HTAVC--------------------------- 3536
Query: 1250 CESQPCQHGGQC-RPSPGPGGGLTFTCHCAQPFWGPRCERVARS 1292
PC +GG+C RP+ CHC + G C R R+
Sbjct: 3537 --QSPCLNGGKCVRPN---------RCHCLSSWTGHNCSRKRRT 3569
Score = 59.7 bits (143), Expect = 3e-08
Identities = 58/217 (26%), Positives = 83/217 (38%), Gaps = 38/217 (17%)
Query: 554 CHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTT 613
C G + G +C P T T+ ++ ++ P H V+ + R
Sbjct: 3384 CREGFLLQGHGIITCN--PDETWTQTSAKCEKISCGPPAH-------VENAIAR------ 3428
Query: 614 GVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGP-LCNVEINECASSPCGEGGSC 672
GV+ + D + C G +G R C+ +T P +C PC GG C
Sbjct: 3429 GVHYQYG--DMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRA----VCRFPCQNGGIC 3482
Query: 673 VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQS 732
+ C CP G + LC P PC +G AP ++C C PGW+G RC +
Sbjct: 3483 ---QRPNACSCPEGWMGRLC---EEPICILPCLNGGRCVAP--YQCDCPPGWTGSRCHTA 3534
Query: 733 LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQC 769
+ C+S PC GG C C C G C
Sbjct: 3535 V----CQS-PCLNGGKCVRPN---RCHCLSSWTGHNC 3563
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/106 (33%), Positives = 43/106 (40%), Gaps = 16/106 (15%)
Query: 285 CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 344
C NGG C ++C C GW G C + I C +G C VA + C CP G
Sbjct: 3476 CQNGGICQRP---NACSCPEGWMGRLCEEPI---CILPCLNGGRC---VAPYQCDCPPGW 3526
Query: 345 TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQ 390
TG CH A +PC C P C C +TG C +
Sbjct: 3527 TGSRCH--TAVCQSPCLNGGKC-VRPNR----CHCLSSWTGHNCSR 3565
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/139 (33%), Positives = 58/139 (41%), Gaps = 44/139 (31%)
Query: 1239 SGPRCQTVLSPCESQPCQHGGQC-RPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQ 1297
S P C+ V C PCQ+GG C RP+ C C + + G R C E
Sbjct: 3464 SPPICRAV---CRF-PCQNGGICQRPN---------ACSCPEGWMG-------RLCEEPI 3503
Query: 1298 CPVGVPCQQTPR--GP-RCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSC-RPA 1353
C +PC R P +C CPPG +G C + + +PCL+GG C RP
Sbjct: 3504 CI--LPCLNGGRCVAPYQCDCPPGWTGSRC-----------HTAVCQSPCLNGGKCVRPN 3550
Query: 1354 PLAPFFRCACAQGWTGPRC 1372
RC C WTG C
Sbjct: 3551 ------RCHCLSSWTGHNC 3563
Score = 52.8 bits (125), Expect = 4e-06
Identities = 40/131 (30%), Positives = 52/131 (39%), Gaps = 13/131 (9%)
Query: 103 RFSCRCP----RGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS- 157
R SC P GF D ++ C +G D R C+ + G S
Sbjct: 1687 RISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLL--GDSRMFCTDNGSWNGVSPSCL 1744
Query: 158 DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT--GPLCENPAVPCAPSPCRNGGTCRQ- 214
DVDEC VG C +CLN GS+ C C YT G C P AP NG + +
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 215 ---SGDLTYDC 222
++T+ C
Sbjct: 1805 YTVGAEVTFSC 1815
Score = 49.3 bits (116), Expect = 4e-05
Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 36/135 (26%)
Query: 1284 PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAP 1343
P C V R C G CQ R C+CP G G C P
Sbjct: 3466 PICRAVCR----FPCQNGGICQ---RPNACSCPEGWMGRLCEE-----------PICILP 3507
Query: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
CL+GG C +AP+ +C C GWTG RC +C R RC
Sbjct: 3508 CLNGGRC----VAPY-QCDCPPGWTGSRCHTAVCQSPCLNGGKCVR--------PNRC-- 3552
Query: 1404 ECNSPGCGWDGGDCS 1418
C S W G +CS
Sbjct: 3553 HCLS---SWTGHNCS 3564
Score = 47.4 bits (111), Expect = 2e-04
Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 796 CSCPQGWQG--PRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDC 853
C+ W G P C DVDECA + C H C N+ GS+ C+C YTG N
Sbjct: 1730 CTDNGSWNGVSPSCL-DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG----DGKNCA 1784
Query: 854 DPNPCLNGGSCQDGVGS 870
+P C G+ ++G S
Sbjct: 1785 EPIKCKAPGNPENGHSS 1801
Score = 47.0 bits (110), Expect = 2e-04
Identities = 27/71 (38%), Positives = 29/71 (40%), Gaps = 13/71 (18%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCR 107
PC NGGRC C CPPGW G RC C S PC G C C
Sbjct: 3507 PCLNGGRCVA----PYQCDCPPGWTGSRCHTA-VCQS-PCLNGGKC-------VRPNRCH 3553
Query: 108 CPRGFRGPDCS 118
C + G +CS
Sbjct: 3554 CLSSWTGHNCS 3564
Score = 42.4 bits (98), Expect = 0.005
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 391 DVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTG 425
DVDEC++G++ EH C+N GS++C C YTG
Sbjct: 1745 DVDECAVGSDCSEHAS-CLNVDGSYICSCVPPYTG 1778
Score = 39.7 bits (91), Expect = 0.035
Identities = 68/294 (23%), Positives = 97/294 (32%), Gaps = 71/294 (24%)
Query: 395 CSIGANPCEHLG--RCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ 452
C G + C+ +G +C G F C C +GY G + + C SG + +
Sbjct: 281 CDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPE--------- 331
Query: 453 FTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF--SGSTCQLDVDE 510
G G I C P N + C C G+ SG TC+L V
Sbjct: 332 -------GSPG-----GISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCEL-VHC 378
Query: 511 CASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCAC 570
A P NG F C+ + + CH G D + S C
Sbjct: 379 PALKPPENGY----------------FIQNTCNNHFNAACGVRCHPG--FDLVGSSIILC 420
Query: 571 APGYTGTRCESQVDECRSQPC------RHGG-KCLDLVDKYLCRC---------PSGTTG 614
P + ES CR + C +HG C Y C G+
Sbjct: 421 LPNGLWSGSESY---CRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 615 VNCEVNID------DCASNPC-TFGVCRDG-INRYDCVCQPGFTGPLCNVEINE 660
+ C+ N C C TF + +D I+ ++C QP G +C V +
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQ 531
Score = 39.3 bits (90), Expect = 0.045
Identities = 68/295 (23%), Positives = 93/295 (31%), Gaps = 67/295 (22%)
Query: 807 CQQDVDEC--AGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD--------------- 849
C + D C G CG H G F C C GY G +
Sbjct: 281 CDEGKDCCDRMGSCKCGTH------TGHFECICEKGYYGKGLQYECTACPSGTYKPEGSP 334
Query: 850 --INDCDPNPCLNGGSCQDGVGSFSCSCLPGF--AGPRCARDVDECLSNPCG----PGTC 901
I+ C P P N S C C G+ +G C L P TC
Sbjct: 335 GGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTC 394
Query: 902 TDHV-ASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
+H A+ C PG+ L C P+ ++G V + L +P +
Sbjct: 395 NNHFNAACGVRCHPGFDLVGSSIIL--CLPNGLWSGSESYCRVRTCPHLRQP-------K 445
Query: 961 HEADPCLSRPCLHGGVC-SAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ-- 1017
H C +R L+ C A G+R LE CQ W +P RCV+
Sbjct: 446 HGHISCSTREMLYKTTCLVACDEGYR---LEGSDKLTCQGNSQWDGPEP-----RCVERH 497
Query: 1018 ------------TGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQ 1060
+ C P G +C + CR+ GV+ C G+
Sbjct: 498 CSTFQMPKDVIISPHNCGKQPAKFGTICYV---SCRQGFILSGVKEMLRCTTSGK 549
Score = 38.9 bits (89), Expect = 0.059
Identities = 67/270 (24%), Positives = 95/270 (35%), Gaps = 46/270 (17%)
Query: 920 HCEQDLPDCSPSSCFNGGTCVDGVNS--FSCLCRPGYTGAHCQHEADPCLSRPCLHGGVC 977
HC L D C G+C G ++ F C+C GY G Q+E C S G
Sbjct: 276 HCSY-LCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPS-----GTYK 329
Query: 978 SAAHPGFRCTCL----ESFTGPQCQTLVDWCSRQPCQNGGRCV-QTGAYCLCP---PGWS 1029
PG +C+ E+ T P T + C C+ G R QT CP P +
Sbjct: 330 PEGSPGGISSCIPCPDENHTSPPGSTSPEDC---VCREGYRASGQTCELVHCPALKPPEN 386
Query: 1030 GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG---RTGSHCEQEVD 1086
G I++ A GVR C G V SS P G + S+C
Sbjct: 387 GYF--IQNTCNNHFNAACGVR----CHPGFDLV--GSSIILCLPNGLWSGSESYCRVRTC 438
Query: 1087 PCLAQPCQHGGTCRGYMGGYMCECL----PGYNGDNCEDDVDECASQPCQHGGSCID--- 1139
P L QP +C Y CL GY + + + SQ C++
Sbjct: 439 PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHC 498
Query: 1140 ---------LVARYLCSCPPGTLGVLCEIN 1160
+++ + C P G +C ++
Sbjct: 499 STFQMPKDVIISPHNCGKQPAKFGTICYVS 528
Score = 38.1 bits (87), Expect = 0.10
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 12/92 (13%)
Query: 835 CTCHGGYTG--PSCDQDINDCDP-NPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVD 889
CT +G + G PSC D+++C + C SC + GS+ CSC+P + G CA +
Sbjct: 1730 CTDNGSWNGVSPSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPI- 1787
Query: 890 ECLS-----NPCGPGTCTDHVASFTCTCPPGY 916
+C + N G A T +C GY
Sbjct: 1788 KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGY 1819
Score = 36.2 bits (82), Expect = 0.38
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 6/74 (8%)
Query: 1084 EVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYNGD--NCEDDVDECASQPCQHG---GSC 1137
+VD C + C +C G Y+C C+P Y GD NC + + A ++G G
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEI 1804
Query: 1138 IDLVARYLCSCPPG 1151
+ A SC G
Sbjct: 1805 YTVGAEVTFSCQEG 1818
Score = 35.8 bits (81), Expect = 0.50
Identities = 35/125 (28%), Positives = 44/125 (35%), Gaps = 24/125 (19%)
Query: 128 CAHGARCSVGPD-GRFLCSCPPGYQGRSCRSDVDECRVGEPCRHG-----GTCL------ 175
C C G G F C C GY G+ + + C G G +C+
Sbjct: 288 CDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDEN 347
Query: 176 --NTPGSFR---CQCPAGY--TGPLCENPAVPCAPSPCRNG----GTCRQSGDLTYDCAC 224
+ PGS C C GY +G CE P A P NG TC + C
Sbjct: 348 HTSPPGSTSPEDCVCREGYRASGQTCELVHCP-ALKPPENGYFIQNTCNNHFNAACGVRC 406
Query: 225 LPGFE 229
PGF+
Sbjct: 407 HPGFD 411
Score = 35.4 bits (80), Expect = 0.66
Identities = 41/156 (26%), Positives = 56/156 (35%), Gaps = 15/156 (9%)
Query: 318 CATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPC----HEDAICDTNPVNG 373
C+ G+ H R AS P K L C V NP ++ P
Sbjct: 1628 CSDCPRLGGSVPHLRTASEDLK-PGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCE 1686
Query: 374 RAICTCPPGFTGGACDQDVDECSIGAN---PCEHLGRCVNTQGSFLCQCGRGYTG--PRC 428
R C PP G D+ G+ C + G + C + G P C
Sbjct: 1687 RISCGVPPPLENGF--HSADDFYAGSTVTYQCNN-GYYLLGDSRMFCTDNGSWNGVSPSC 1743
Query: 429 ETDVNECLSGP-CRNQATCLDRIGQFTCICMAGFTG 463
DV+EC G C A+CL+ G + C C+ +TG
Sbjct: 1744 -LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 35.0 bits (79), Expect = 0.86
Identities = 64/296 (21%), Positives = 83/296 (28%), Gaps = 75/296 (25%)
Query: 541 LCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDL 600
LCD D C D +C F C C GY G + + C S +
Sbjct: 280 LCDEGKDCC--DRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYK-------- 329
Query: 601 VDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDG-INRYDCVCQPGFTGPLCNVEIN 659
P G+ G I C P G + DCVC+ G+ E+
Sbjct: 330 --------PEGSPG-----GISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELV 376
Query: 660 ECASSPCGEGGSCVDG--ENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
C + E G + N F C P +D G
Sbjct: 377 HCPALKPPENGYFIQNTCNNHFNAACGVRCHPG-------------------FDLVGSSI 417
Query: 718 CVCEPG--WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC 775
+C P WSG + QP +CS+ M + TC
Sbjct: 418 ILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA------------ 465
Query: 776 TPNPCEHGGRCESAPGQLPVCSCPQGWQG--PRC--------QQDVDECAGPAPCG 821
C+ G R E + C W G PRC Q D P CG
Sbjct: 466 ----CDEGYRLEGS--DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCG 515
Score = 34.7 bits (78), Expect = 1.1
Identities = 48/200 (24%), Positives = 67/200 (33%), Gaps = 58/200 (29%)
Query: 125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQ 184
S P A + P + C PG+Q VG P ++ CLN
Sbjct: 1637 SVPHLRTASEDLKPGSKVNLFCDPGFQ-----------LVGNPVQY---CLNQ------- 1675
Query: 185 CPAGYTGPLCENPAVPCA-PSPCRNGGTCRQS----GDLTYDCACLPGFEGQNCEVNVDD 239
+T PL + C P P NG +TY C
Sbjct: 1676 --GQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQC----------------- 1716
Query: 240 CPGHRCLNGGTCVDGVNTYNCQCPPEWTG--QFCTEDVDECQLQPNACHNGGTCFNTLGG 297
N G + G + C W G C DVDEC + + C +C N G
Sbjct: 1717 -------NNGYYLLGDSRMFCTDNGSWNGVSPSCL-DVDECAVGSD-CSEHASCLNVDGS 1767
Query: 298 HSCVCVNGWTGE--SCSQNI 315
+ C CV +TG+ +C++ I
Sbjct: 1768 YICSCVPPYTGDGKNCAEPI 1787
Score = 34.7 bits (78), Expect = 1.1
Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 1122 DVDECA-SQPCQHGGSCIDLVARYLCSCPPGTLG 1154
DVDECA C SC+++ Y+CSC P G
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 33.5 bits (75), Expect = 2.5
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 8/90 (8%)
Query: 493 CTCPSGFSG-STCQLDVDECA-STPCRNGAKCVDQPDGYECRCAEGF--EGTLCDRNVDD 548
CT ++G S LDVDECA + C A C++ Y C C + +G C +
Sbjct: 1730 CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKC 1789
Query: 549 CSPDPCHHGRCVDGI----ASFSCACAPGY 574
+P +G I A + +C GY
Sbjct: 1790 KAPGNPENGHSSGEIYTVGAEVTFSCQEGY 1819
Score = 32.7 bits (73), Expect = 4.3
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 4/30 (13%)
Query: 47 SPCANGGRCTQLPSREAACLCPPGWVGERC 76
SPC NGG+C + P+R C C W G C
Sbjct: 3538 SPCLNGGKCVR-PNR---CHCLSSWTGHNC 3563
Score = 32.3 bits (72), Expect = 5.6
Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 14/107 (13%)
Query: 629 CTFGVCRDGINRYDCVCQPGFTG--PLCNVEINECA-SSPCGEGGSCVDGENGFRCLCPP 685
C G G +R C + G P C ++++ECA S C E SC++ + + C C P
Sbjct: 1716 CNNGYYLLGDSRMFCTDNGSWNGVSPSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVP 1774
Query: 686 G--------SLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGW 724
+ P C P +P S G Y C+ G+
Sbjct: 1775 PYTGDGKNCAEPIKCKAPGNP--ENGHSSGEIYTVGAEVTFSCQEGY 1819
Score = 31.6 bits (70), Expect = 9.5
Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Query: 545 NVDDCS--PDPCHHGRCVDGIASFSCACAPGYTG 576
+VD+C+ D H C++ S+ C+C P YTG
Sbjct: 1745 DVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 256 bits (654), Expect = 2e-67
Identities = 265/998 (26%), Positives = 367/998 (36%), Gaps = 226/998 (22%)
Query: 392 VDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE---TDVNECLSGPCRNQATCLD 448
+D C+ GA G CVN + C C GY + TD NECL PC+ + C++
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 449 RIGQFTCICMAGFT-----GTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF---S 500
R+G ++C C G+T T DI+EC+ +GG C + + C C G+
Sbjct: 905 RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVR 964
Query: 501 GSTCQLDVDECASTPCRNGAKCVDQPDGYEC-RCAEGFEGTLCDR-NVDDC-SPDPCHHG 557
CQ D++EC +CV+ P Y C C EG+ G +V++C +P C HG
Sbjct: 965 KGHCQ-DINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHG 1023
Query: 558 RCVDGIASFSCACAPGYTGTRCES---QVDECRSQPCRHGGKCLDLVDKYLCR------- 607
+C + SF C+C GY T E VDEC S+ G CL+ + C
Sbjct: 1024 KCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYW 1083
Query: 608 -------------------CPSGTT---------------------GVNCEVNIDDCAS- 626
CPSG G +CE ++D+C
Sbjct: 1084 VNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDP 1142
Query: 627 -NPCTFGVCRDGINRYDCVCQPGF---TGPLCNVEINECASSP-CGEGGSCVDGENGFRC 681
+ C G C++ + Y C+C GF G +C ++NEC C G C++ F C
Sbjct: 1143 QSSCLGGECKNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFC 1201
Query: 682 LCPPGSLPP----LCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWS-GPRCSQSLARD 736
LC PG + C +PC G C + G F C+CE G+ P + + D
Sbjct: 1202 LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDID 1261
Query: 737 ACESQPCRAGGT--CSSDGMGFHCT--CPPGVQ---GRQCELLSPCTPNP-CEHGGRCES 788
CE GT C + + C C PG C + C + C G C++
Sbjct: 1262 ECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFCDN 1321
Query: 789 APGQLPVCSCPQGWQ----GPRCQQDVDECAGP-APCGPHGICTNLAGSFSCTCHG---- 839
G C C QG++ G C DV+EC A CG +C N+ GSF C C
Sbjct: 1322 TDGSFR-CLCDQGFEISPSGWDCV-DVNECELMLAVCGA-ALCENVEGSFLCLCASDLEE 1378
Query: 840 -----------GYTGPSCDQ-DINDCDPNP----CLNG----GSCQDGVG----SFSCSC 875
G G S + D P P C +G C +G C C
Sbjct: 1379 YDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCC 1438
Query: 876 LPGFA-----------------------------------GPRCARDVDECL---SNPCG 897
G + G D DEC+ C
Sbjct: 1439 TQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCP 1498
Query: 898 PGTCTDHVASFTCTCPPG--YGGFH--CEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPG 953
G C + V + C C PG Y H CE D +C +C NG CV+ SF C C P
Sbjct: 1499 NGRCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPP 1556
Query: 954 YT----GAHCQHEADPCLSRPC--LHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ 1007
T C + P +H +C C+ E G + T + C
Sbjct: 1557 LTLDLSQQRCMNSTSSTEDLPDHDIHMDICWKKVTNDVCS--EPLRGHRT-TYTECC--- 1610
Query: 1008 PCQNGGRCVQTGAYCLCPPGWS---GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1064
CQ+G Q A LCPP S +LC++ + EA + GV + G
Sbjct: 1611 -CQDGEAWSQQCA--LCPPRSSEVYAQLCNVARI---EAEREAGVHFRPGYEYGP---GP 1661
Query: 1065 DSSHYCVC-PEG-------------------RTGSHCEQEVDPCLAQPCQHGGTCRGYMG 1104
D HY + P+G T H P L P Q Y+
Sbjct: 1662 DDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRT-PILESPLQPSELQPHYVA 1720
Query: 1105 GYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPG----TLGVLC-EI 1159
+ E G+ G E EC G C+ + Y C C G + C ++
Sbjct: 1721 SHP-EPPAGFEGLQAE----ECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDV 1775
Query: 1160 NEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY 1197
NE D GP + C+H G C + G +RC C PGY
Sbjct: 1776 NECDDLNGPAV----LCVH-GYCENTEGSYRCHCSPGY 1808
Score = 244 bits (622), Expect = 9e-64
Identities = 282/1020 (27%), Positives = 405/1020 (39%), Gaps = 207/1020 (20%)
Query: 29 LLLLLAGPGAAAPPCLDGSPCANG-GRCTQLPSREAACLCPPGWV----GERCQLEDPCH 83
+L+ L+ PG C G+ G G C LP C+C PG+ C ++ C
Sbjct: 836 VLVTLSTPGIDR--CAAGATNVCGPGTCVNLPDGYR-CVCSPGYQLHPSQAYCTDDNECL 892
Query: 84 SGPCAGRGVCQSSVVAGTARFSCRCPRGF------RGPDCSLPDPCLSSPCAHGARCSVG 137
PC G+G C + V +SC C G+ +C + C G +C+
Sbjct: 893 RDPCKGKGRCINRV----GSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCT-N 947
Query: 138 PDGRFLCSCPPGY---QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRC-QCPAGYTGP- 192
+G + C C GY + C+ D++ECR C G C+N+PGS+ C C GY G
Sbjct: 948 TEGSYHCECDQGYIMVRKGHCQ-DINECRHPGTC-PDGRCVNSPGSYTCLACEEGYRGQS 1005
Query: 193 -LCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE---VNVDDCPGHRCLNG 248
C + P C +G G ++ C+C G+E + E +VD+C
Sbjct: 1006 GSCVDVNECLTPGVCAHGKCTNLEG--SFRCSCEQGYEVTSDEKGCQDVDECASRASCPT 1063
Query: 249 GTCVDGVNTYNCQCPPE--WTGQFCT--EDVDECQLQPNACHNGGTCFNTLGGHSCV-CV 303
G C++ ++ C W + T ED+DEC P C + G C NT G SC C
Sbjct: 1064 GLCLNTEGSFACSACENGYWVNEDGTACEDLDECAF-PGVCPS-GVCTNTAGSFSCKDCD 1121
Query: 304 NGW----TGESCSQNIDDC--ATAVCFHGATCHDRVASFYCACPMG---KTGLLCHLDDA 354
G+ G+SC +++D+C + C G C + V S+ C CP G G +C +
Sbjct: 1122 GGYRPSPLGDSC-EDVDECEDPQSSCL-GGECKNTVGSYQCLCPQGFQLANGTVCEDVNE 1179
Query: 355 CVSNP-CHEDAICDTNPVNGRAICTCPPGFT---GGACDQDVDECSIGANPCEHLGRCVN 410
C+ C C + +G C C PGF GG QDVDEC+ +PC G CVN
Sbjct: 1180 CMGEEHCAPHGECLNS--HGSFFCLCAPGFVSAEGGTSCQDVDECAT-TDPCVG-GHCVN 1235
Query: 411 TQGSFLCQCGRGYTGPRCET----DVNEC--LSGPCRNQATCLDRIGQFTCI--CMAGF- 461
T+GSF C C G+ P E+ D++EC P C + G + C+ C GF
Sbjct: 1236 TEGSFNCLCETGFQ-PSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFH 1294
Query: 462 --TGTYCEVDIDEC-QSSPCVNGGVCKDRVNGFSCTCPSGF----SGSTCQLDVDECAST 514
C +DIDEC + C + G C + F C C GF SG C +DV+EC
Sbjct: 1295 MAPNGDC-IDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDC-VDVNECELM 1352
Query: 515 PCRNGAKCVDQPDG-YECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPG 573
GA + +G + C CA E D C P G+ + + A AP
Sbjct: 1353 LAVCGAALCENVEGSFLCLCASDLEE--YDAQEGHCRPRGA-GGQSMSEAPTGDHAPAPT 1409
Query: 574 ----YTGTR----CES-------QVDECRSQPCRHGGKCLDLVD-----KYLCRCPSG-- 611
Y+G + C S Q + C +Q G C DL ++ CPSG
Sbjct: 1410 RMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDAC-DLCPSEDSAEFSEICPSGKG 1468
Query: 612 --------TTGVNCEVNIDDC---ASNPCTFGVCRDGINRYDCVCQPGF----TGPLCNV 656
T G + D+C C G C + + Y C+C PGF + C
Sbjct: 1469 YIPVEGAWTFGQTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE- 1527
Query: 657 EINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLP----------------PSHPCA 700
+ +EC C E G CV+ E F C C PPL L P H
Sbjct: 1528 DHDECQDLAC-ENGECVNTEGSFHCFCS----PPLTLDLSQQRCMNSTSSTEDLPDHDIH 1582
Query: 701 HEPC----SHGICYDAPGGFR-----CVCEPG--WS------GPRCSQSLAR--DACESQ 741
+ C ++ +C + G R C C+ G WS PR S+ A+ + +
Sbjct: 1583 MDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIE 1642
Query: 742 PCRAGGT---------CSSDGMGFHCTCPPGVQ-----GRQCELLSPCTPNPCEHGG--- 784
R G D + + P G G + + P PN H
Sbjct: 1643 AEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHSADRT 1702
Query: 785 ---RCESAPGQLP---VCSCPQ---GWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSC 835
P +L V S P+ G++G +EC C +G C + ++C
Sbjct: 1703 PILESPLQPSELQPHYVASHPEPPAGFEG----LQAEECGILNGC-ENGRCVRVREGYTC 1757
Query: 836 TCHGGYTGPSCDQ---DINDCDPNPCLNG-------GSCQDGVGSFSCSCLPGF---AGP 882
C G+ + D+N+CD LNG G C++ GS+ C C PG+ AGP
Sbjct: 1758 DCFEGFQLDAAHMACVDVNECDD---LNGPAVLCVHGYCENTEGSYRCHCSPGYVAEAGP 1814
Score = 239 bits (610), Expect = 2e-62
Identities = 269/1017 (26%), Positives = 381/1017 (37%), Gaps = 168/1017 (16%)
Query: 369 NPVNGRAICTCPPGFTGGACD--QDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGY--- 423
+PV CP G+ QD++EC + C+ CVNT+GS+LC C G
Sbjct: 598 SPVIENGQLECPQGYKRLNLTHCQDINEC-LTLGLCKD-AECVNTRGSYLCTCRPGLMLD 655
Query: 424 -TGPRCETD-VNECLSGPCRNQ---ATCLDRIGQFTC--ICMAGFTGTYCEVDIDECQSS 476
+ RC +D L G C TC + Q IC G EC+
Sbjct: 656 PSRSRCVSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCCSRVGKAWG---SECEKC 712
Query: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV---------DECASTPCRNGAKCVDQPD 527
P F CP+G + D+ +E A P G +
Sbjct: 713 PLPG-------TEAFREICPAGHGYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALP 765
Query: 528 GYECRCAEGF-------EGTLCDRN---VDDCSPDPCHHGRCVDGIASFSCACAPGYTGT 577
G R GT+ D+ + H V G A+ G
Sbjct: 766 GPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEI 825
Query: 578 RCESQ--------------VDECRSQPCR--HGGKCLDLVDKYLCRCPSG----TTGVNC 617
+ E +D C + G C++L D Y C C G + C
Sbjct: 826 QEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYC 885
Query: 618 EVNIDDCASNPCTF-GVCRDGINRYDCVCQPGFTGPLCNV-----EINECASSPCGEGGS 671
+ ++C +PC G C + + Y C C PG+T +INEC GG
Sbjct: 886 -TDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQ 944
Query: 672 CVDGENGFRCLCPPGSLPPLCLPPSH-----PCAHE-PCSHGICYDAPGGFRCV-CEPGW 724
C + E + C C G + + H C H C G C ++PG + C+ CE G+
Sbjct: 945 CTNTEGSYHCECDQGYI---MVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGY 1001
Query: 725 SGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQCELLSPCTPNPC 780
G + + + C + A G C++ F C+C G + + C+ + C
Sbjct: 1002 RG-QSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRAS 1060
Query: 781 EHGGRCESAPGQLPVCSCPQGW----QGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCT 836
G C + G +C G+ G C+ D+DECA P C P G+CTN AGSFSC
Sbjct: 1061 CPTGLCLNTEGSFACSACENGYWVNEDGTACE-DLDECAFPGVC-PSGVCTNTAGSFSCK 1118
Query: 837 -CHGGYT----GPSCDQDINDC-DPNPCLNGGSCQDGVGSFSCSCLPGF--AGPRCARDV 888
C GGY G SC+ D+++C DP GG C++ VGS+ C C GF A DV
Sbjct: 1119 DCDGGYRPSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDV 1177
Query: 889 DECLSNP-CGP-GTCTDHVASFTCTCPPGY----GGFHCEQDLPDCSPSSCFNGGTCVDG 942
+EC+ C P G C + SF C C PG+ GG C QD+ +C+ + GG CV+
Sbjct: 1178 NECMGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSC-QDVDECATTDPCVGGHCVNT 1236
Query: 943 VNSFSCLCRPGYTGAHCQHEA---DPC--LSRPCLHGGVCSAAHPGFRCT--CLESF--- 992
SF+CLC G+ + E D C P C + +RC C F
Sbjct: 1237 EGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMA 1296
Query: 993 TGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLC-------PPGWSG---RLCDIRSLPC 1040
C + + + C + G C T G++ CLC P GW C++ C
Sbjct: 1297 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC 1356
Query: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCR 1100
A + V LC + D+ P G G + A
Sbjct: 1357 GAALCE-NVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYS 1415
Query: 1101 GYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLV-----ARYLCSCPPG---- 1151
G G C + G N E C +Q G +C DL A + CP G
Sbjct: 1416 GQKGHAPCSSVLGRNTTQAEC----CCTQGASWGDAC-DLCPSEDSAEFSEICPSGKGYI 1470
Query: 1152 ------TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLR 1201
T G + D+C + GP NG C++ V G+ C C PG+ + +
Sbjct: 1471 PVEGAWTFGQTMYTDADEC-----VIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKK 1525
Query: 1202 CEADINECRSGACHAAHTRDCLQDPGGGFRCLCH----AGFSGPRCQTVLSPCESQP 1254
CE D +EC+ AC +C+ + G F C C S RC S E P
Sbjct: 1526 CE-DHDECQDLAC---ENGECV-NTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLP 1577
Score = 186 bits (472), Expect = 2e-46
Identities = 238/893 (26%), Positives = 322/893 (36%), Gaps = 134/893 (15%)
Query: 549 CSPDPCHHGRCVDGIASFSCACAPGYTG---TRCESQVDECRSQPCRHGGKCLDLVDKYL 605
C+P P V I + C GY T C+ ++EC + +C++ YL
Sbjct: 589 CAPCPPRPASPV--IENGQLECPQGYKRLNLTHCQD-INECLTLGLCKDAECVNTRGSYL 645
Query: 606 CRCPSGTTGVNCEVNIDDCASNPCTF---GVCRDGINRYDCVCQPGFTGPLCN-VEINEC 661
C C G+ + + C S+ G+C + C T PL + C
Sbjct: 646 CTC---RPGLMLDPSRSRCVSDKAISMLQGLCYRSLGPGTC------TLPLAQRITKQIC 696
Query: 662 ASSPCGE--GGSC----VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGG 715
S G+ G C + G FR +CP G H + +
Sbjct: 697 CCSRVGKAWGSECEKCPLPGTEAFREICPAG----------HGYTYASSDIRLSMRKAEE 746
Query: 716 FRCVCEPGWSGPRCSQSLARDACESQPCRA-------GGTCSSDGMGFHCTCPPGVQGRQ 768
P G R S +L A E QP R GT G V
Sbjct: 747 EELARPPREQGQRSSGALPGPA-ERQPLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTHAP 805
Query: 769 CELLSPCTPNPCEHGGRCESAPGQL-PVCSCPQGWQGPRCQQDVDECAGPAP--CGPHGI 825
+ T P G E Q+ P P +D CA A CGP G
Sbjct: 806 AWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTP----GIDRCAAGATNVCGP-GT 860
Query: 826 CTNLAGSFSCTCHGGYT-GPS---CDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF-- 879
C NL + C C GY PS C D N+C +PC G C + VGS+SC C PG+
Sbjct: 861 CVNLPDGYRCVCSPGYQLHPSQAYCTDD-NECLRDPCKGKGRCINRVGSYSCFCYPGYTL 919
Query: 880 ----AGPRCARDVDEC-LSNPCGPGTCTDHVASFTCTCPPGY---GGFHCEQDLPDCSPS 931
A C +D++EC C G CT+ S+ C C GY HC QD+ +C
Sbjct: 920 ATSGATQEC-QDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHC-QDINECRHP 977
Query: 932 SCFNGGTCVDGVNSFSCL-CRPGYTG--AHCQHEADPCLSRPCLHGGVCSAAHPGFRCTC 988
G CV+ S++CL C GY G C + + CL+ G C+ FRC+C
Sbjct: 978 GTCPDGRCVNSPGSYTCLACEEGYRGQSGSCV-DVNECLTPGVCAHGKCTNLEGSFRCSC 1036
Query: 989 LESFTGPQ----CQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAA 1044
+ + CQ + + SR C G C+ T C +G + C +
Sbjct: 1037 EQGYEVTSDEKGCQDVDECASRASCPT-GLCLNTEGSFACSACENGYWVNEDGTACEDLD 1095
Query: 1045 AQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG-----RTGSHCEQEVDPCL-AQPCQHGGT 1098
+C + G C + S C +G G CE +VD C Q GG
Sbjct: 1096 E---CAFPGVCPS-GVCTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDECEDPQSSCLGGE 1150
Query: 1099 CRGYMGGYMCECLPGY---NGDNCEDDVDEC-ASQPCQHGGSCIDLVARYLCSCPPGTL- 1153
C+ +G Y C C G+ NG CE DV+EC + C G C++ + C C PG +
Sbjct: 1151 CKNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCAPHGECLNSHGSFFCLCAPGFVS 1209
Query: 1154 ---GVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY----TGLRCEADI 1206
G C+ + D+C P C+ G CV+ G F C C G+ C DI
Sbjct: 1210 AEGGTSCQ-DVDECATTDP------CV-GGHCVNTEGSFNCLCETGFQPSPESGEC-VDI 1260
Query: 1207 NECRSGACHAAHTRDCLQDPGGGFRCL--CHAGF---SGPRCQTVLSPCESQPCQHGGQC 1261
+EC T C P G +RC+ C GF C + C G C
Sbjct: 1261 DECEDYGDPVCGTWKCENSP-GSYRCVLGCQPGFHMAPNGDCIDIDECANDTMCGSHGFC 1319
Query: 1262 RPSPGPGGGLTFTCHCAQPF----WGPRCERVARSCRELQCPVGVP-CQQTPRGPRCACP 1316
+ G +F C C Q F G C V C + G C+ C C
Sbjct: 1320 DNTDG-----SFRCLCDQGFEISPSGWDCVDV-NECELMLAVCGAALCENVEGSFLCLCA 1373
Query: 1317 PGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTG 1369
L + P GA S + AP G PAP R C G G
Sbjct: 1374 SDLEEYDAQEGHCRPRGAGGQSMSEAPT---GDHAPAPT----RMDCYSGQKG 1419
Score = 123 bits (309), Expect = 2e-27
Identities = 147/569 (25%), Positives = 204/569 (35%), Gaps = 107/569 (18%)
Query: 975 GVCSAAHPGFRCTCLESFTGPQCQTLV---DWCSRQPCQNGGRCV-QTGAY-CLCPPGWS 1029
G C G+RC C + Q + C R PC+ GRC+ + G+Y C C PG++
Sbjct: 859 GTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYT 918
Query: 1030 GRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEG----RTGSHCEQEV 1085
+ + + I + +GGQC + + S++C C +G R G HC Q++
Sbjct: 919 -----LATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKG-HC-QDI 971
Query: 1086 DPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGDNCED-DVDECASQPCQHGGSCIDLVAR 1143
+ C G C G Y C C GY G + DV+EC + G C +L
Sbjct: 972 NECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGS 1031
Query: 1144 YLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRC-LHNGTCVDLVGGFRCT-CPPGY---- 1197
+ CSC G E+ D+ G + R G C++ G F C+ C GY
Sbjct: 1032 FRCSCEQGY-----EVTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE 1086
Query: 1198 TGLRCEADINECR-SGACHAAHTRDCLQDPGGGFRCL-CHAGFS----GPRCQTVLSPCE 1251
G CE D++EC G C + + G F C C G+ G C+ V +
Sbjct: 1087 DGTACE-DLDECAFPGVCPSG----VCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECED 1141
Query: 1252 SQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW---GPRCERVARSCRELQCPVGVPCQQTP 1308
Q GG+C+ + G ++ C C Q F G CE V E C C +
Sbjct: 1142 PQSSCLGGECKNTVG-----SYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNSH 1196
Query: 1309 RGPRCACPPGL----SGPSCRSFPGSPPGASNASCAAA-PCLHGGSCRPAPLAPFFRCAC 1363
C C PG G SC+ CA PC+ GG C F C C
Sbjct: 1197 GSFFCLCAPGFVSAEGGTSCQDVD---------ECATTDPCV-GGHC--VNTEGSFNCLC 1244
Query: 1364 AQGWT-GPRCEAPAAAPEVSE--EPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLS 1420
G+ P E + +P C C+ G RC C GDC
Sbjct: 1245 ETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCI-- 1302
Query: 1421 VGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFA 1480
D C ++ CD S CL
Sbjct: 1303 --DIDECANDTMCG---SHGFCDNTDGSFRCL---------------------------- 1329
Query: 1481 DGRCDQGCNTEECGWDGLDCASEVPALLA 1509
CDQG GWD +D +E +LA
Sbjct: 1330 ---CDQGFEISPSGWDCVD-VNECELMLA 1354
Score = 80.9 bits (198), Expect = 1e-14
Identities = 142/570 (24%), Positives = 188/570 (32%), Gaps = 110/570 (19%)
Query: 892 LSNPCGPGTCTDHVASFTCTCPPGYGGF---HCEQDLPDCSPSSCFNGGTCVDGVNSFSC 948
L PC P + + + CP GY HC QD+ +C CV+ S+ C
Sbjct: 588 LCAPCPPRPASPVIENGQLECPQGYKRLNLTHC-QDINECLTLGLCKDAECVNTRGSYLC 646
Query: 949 LCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQ-TLVDWCSRQ 1007
CRPG DP SR C V A + C S C L ++Q
Sbjct: 647 TCRPGLM-------LDPSRSR-C----VSDKAISMLQGLCYRSLGPGTCTLPLAQRITKQ 694
Query: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSS 1067
C C + G W G C+ LP EA ++C AG
Sbjct: 695 IC----CCSRVG------KAW-GSECEKCPLPGTEA-------FREICPAG--------H 728
Query: 1068 HYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP-------GYNGDNCE 1120
Y S + E + P + G G + G E P
Sbjct: 729 GYTYASSDIRLSMRKAEEEELARPPREQGQRSSGALPG-PAERQPLRVVTDTWLEAGTIP 787
Query: 1121 DDVDECASQ---PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPG---------P 1168
D D A Q H + + A + PP + EI E+ P P
Sbjct: 788 DKGDSQAGQVTTSVTHAPAWVTGNA----TTPPMPEQGIAEIQEEQVTPSTDVLVTLSTP 843
Query: 1169 PLDSGPRCLHNGT-------CVDLVGGFRCTCPPGYTGLRCEA---DINECRSGACHAAH 1218
+D RC T CV+L G+RC C PGY +A D NEC C
Sbjct: 844 GID---RCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKG 900
Query: 1219 TRDCLQDPGGGFRCLCHAGF------SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLT 1272
C+ + G + C C+ G+ + CQ + + CE GGQC + G +
Sbjct: 901 R--CI-NRVGSYSCFCYPGYTLATSGATQECQDI-NECEQPGVCSGGQCTNTEG-----S 951
Query: 1273 FTCHCAQPFWGPR---CERVARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSGPSCRSFP 1328
+ C C Q + R C+ + CP G C +P C AC G G S
Sbjct: 952 YHCECDQGYIMVRKGHCQDINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQS----- 1005
Query: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA-APEVSEEPRC 1387
GS N C HG + L FRC+C QG+ E E + C
Sbjct: 1006 GSCVDV-NECLTPGVCAHG---KCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASC 1061
Query: 1388 PRAACQAKRGDQRCDRECNSPGCGWDGGDC 1417
P C G C N DG C
Sbjct: 1062 PTGLCLNTEGSFACSACENGYWVNEDGTAC 1091
Score = 57.4 bits (137), Expect = 2e-07
Identities = 112/484 (23%), Positives = 160/484 (33%), Gaps = 103/484 (21%)
Query: 31 LLLAGPGAAAPPCLDGS-PCANGGRCTQLPSREAACLCPPGWVGERCQLEDP-------- 81
L+LA GAA ++GS C + ++E C P G + E P
Sbjct: 1351 LMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCR--PRGAGGQSMSEAPTGDHAPAP 1408
Query: 82 ----CHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCS-V 136
C+SG G C S + T + C C +G S D C P A S +
Sbjct: 1409 TRMDCYSGQ-KGHAPCSSVLGRNTTQAECCCTQG-----ASWGDACDLCPSEDSAEFSEI 1462
Query: 137 GPDGRFLCSCPPGYQ-GRSCRSDVDECRVGEP--CRHGGTCLNTPGSFRCQCPAGY---- 189
P G+ + G++ +D DEC + P C +G CLNT + C C G+
Sbjct: 1463 CPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPNG-RCLNTVPGYVCLCNPGFHYDA 1521
Query: 190 TGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLP----GFEGQNC------------ 233
+ CE+ C C NG G ++ C C P Q C
Sbjct: 1522 SHKKCEDHD-ECQDLACENGECVNTEG--SFHCFCSPPLTLDLSQQRCMNSTSSTEDLPD 1578
Query: 234 -EVNVDDC-------------PGHRCLNGGTCVDGVNTYNCQC---PP---EWTGQFCTE 273
++++D C GHR C ++ QC PP E Q C
Sbjct: 1579 HDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNV 1638
Query: 274 DVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI--DDCATAVCFHGATCHD 331
E + + G + + G G + +D F H
Sbjct: 1639 ARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAPFYNYLGPEDTVPEPAFPNTAGHS 1698
Query: 332 RVASFYCACPMGKTGLLCHLDDACVSNPCHEDAI----------CDTNPVNGRAI----- 376
+ P+ + L H + P + + C+ NGR +
Sbjct: 1699 ADRTPILESPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCE----NGRCVRVREG 1754
Query: 377 --CTCPPGFTGGACDQ---DVDECSIGANP---CEHLGRCVNTQGSFLCQCGRGYTG--- 425
C C GF A DV+EC P C H G C NT+GS+ C C GY
Sbjct: 1755 YTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVH-GYCENTEGSYRCHCSPGYVAEAG 1813
Query: 426 -PRC 428
P C
Sbjct: 1814 PPHC 1817
Score = 50.4 bits (119), Expect = 2e-05
Identities = 145/648 (22%), Positives = 213/648 (32%), Gaps = 166/648 (25%)
Query: 371 VNGRAIC--TCPPGFTGGACDQDVDEC--SIGANPCEHLGRCVNTQGSFLCQCGRGYTGP 426
+ GR +C C PG+T + C + PC++ G C Q LC C G+ G
Sbjct: 163 LTGRNVCGGQCCPGWTTA---NSTNHCIKPVCEPPCQNRGSCSRPQ---LCVCRSGFRGA 216
Query: 427 RCETDVNECLSGPCRNQAT---CLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV 483
RCE + + P ++ +R AG GT QS P
Sbjct: 217 RCEEVIPDEEFDPQNSRLAPRRWAERSPNLRRSSAAG-EGTLARAQPPAPQSPPAPQSPP 275
Query: 484 CKDRVNGFSCTCPS----GFSGSTCQLDVDECASTPCRNGA----KCVDQPDGYECRCAE 535
++G S T PS G S T +L AS+ + A ++Q DG +
Sbjct: 276 A-GTLSGLSQTHPSQQHVGLS-RTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPL 333
Query: 536 GFEGTLCDRNVDD------------CSPDPCHHGRCVDGIASFSCACAPGYTGT------ 577
+ N+ + C G C + +C G T T
Sbjct: 334 EHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCAN-------SCERGDTTTLYSQGG 386
Query: 578 -----RCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG 632
+ ++ C+ PC +GG+C + + C CP+ +TG C + I P G
Sbjct: 387 HGHDPKSGFRIYFCQI-PCLNGGRC---IGRDECWCPANSTGKFCHLPIPQPDREPPGRG 442
Query: 633 VCRDGINRYDCVCQPGFTGPLCN---------------------VEINECASSPCGEGGS 671
R + Q FT PL N V+I++ A G +
Sbjct: 443 -SRPRALLEAPLKQSTFTLPLSNQLASVNPSLVKVHIHHPPEASVQIHQVAQVRGGVEEA 501
Query: 672 CVDGENGFRCLCPP-------------------GSLPPLCLPPSHPCAHEPCSHGICYDA 712
V EN PP PP LPP+ P
Sbjct: 502 LV--ENSVETRPPPWLPASPGHSLWDSNNIPARSGEPPRPLPPAAP-------------R 546
Query: 713 PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELL 772
P G C +C+ L + + C C S G + T L
Sbjct: 547 PRGLLGRCYLNTVNGQCANPLL-ELTTQEDC-----CGSVGAFWGVT-----------LC 589
Query: 773 SPCTPNPCEHGGRCESAPGQLPVCSCPQGWQG---PRCQQDVDECAGPAPCGPHGICTNL 829
+PC P P GQL CPQG++ C QD++EC C C N
Sbjct: 590 APCPPRPASP----VIENGQL---ECPQGYKRLNLTHC-QDINECLTLGLC-KDAECVNT 640
Query: 830 AGSFSCTCHGG-YTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCS-----------CLP 877
GS+ CTC G PS + ++ D + G C +G +C+ C
Sbjct: 641 RGSYLCTCRPGLMLDPSRSRCVS--DKAISMLQGLCYRSLGPGTCTLPLAQRITKQICCC 698
Query: 878 GFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL 925
G + ++C PGT +F CP G+G + D+
Sbjct: 699 SRVGKAWGSECEKCPL----PGT-----EAFREICPAGHGYTYASSDI 737
Score = 39.3 bits (90), Expect = 0.045
Identities = 35/118 (29%), Positives = 38/118 (32%), Gaps = 21/118 (17%)
Query: 10 RRRRPMSPPPPPPPVRALPLLLLLAGP--GAAAPPCLDGSPCANGGRCTQLPSREAACLC 67
RR P+ P P RA P L L P AAPP C C
Sbjct: 122 RRSTPLGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPRGRLTGRNVC--------GGQC 173
Query: 68 PPGWVGERCQLE--DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCS--LPD 121
PGW P PC RG C + C C GFRG C +PD
Sbjct: 174 CPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQL-------CVCRSGFRGARCEEVIPD 224
Score = 37.0 bits (84), Expect = 0.23
Identities = 34/114 (29%), Positives = 44/114 (38%), Gaps = 14/114 (12%)
Query: 136 VGPDGRFLCSCPPGYQGRSCRSDVDEC--RVGEPCRHGGTCLNTP-----GSFRC--QCP 186
V P + S P G Q + R+ R+G P R G P G C QC
Sbjct: 115 VQPPAQTRRSTPLGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPRGRLTGRNVCGGQCC 174
Query: 187 AGYTGPLCENPAV-PCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDD 239
G+T N + P PC+N G+C + C C GF G CE + D
Sbjct: 175 PGWTTANSTNHCIKPVCEPPCQNRGSCSRP----QLCVCRSGFRGARCEEVIPD 224
Score = 36.2 bits (82), Expect = 0.38
Identities = 19/68 (27%), Positives = 28/68 (41%), Gaps = 13/68 (19%)
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGD 1117
GGQC CP T + + P PCQ+ G+C +C C G+ G
Sbjct: 170 GGQC----------CPGWTTANSTNHCIKPVCEPPCQNRGSC---SRPQLCVCRSGFRGA 216
Query: 1118 NCEDDVDE 1125
CE+ + +
Sbjct: 217 RCEEVIPD 224
Score = 35.8 bits (81), Expect = 0.50
Identities = 48/166 (28%), Positives = 57/166 (34%), Gaps = 38/166 (22%)
Query: 721 EPGWSGPRC-SQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779
+PGW PR +++ AR +Q R P Q R+ L P P
Sbjct: 89 QPGWGSPRRPTEAEARRPSRAQQSRR--------------VQPPAQTRRSTPLGQQQPAP 134
Query: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG 839
R +AP LP PQ A P P P G T C G
Sbjct: 135 -----RTRAAPA-LPRLGTPQR----------SGAAPPTP--PRGRLTGRNVCGGQCCPG 176
Query: 840 GYTGPSCDQDIND-CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRC 884
T S + I C+P PC N GSC C C GF G RC
Sbjct: 177 WTTANSTNHCIKPVCEP-PCQNRGSCS---RPQLCVCRSGFRGARC 218
Score = 34.3 bits (77), Expect = 1.5
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 254 GVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQ 313
G N QC P WT T + +P C N G+C CVC +G+ G C +
Sbjct: 165 GRNVCGGQCCPGWTTANSTNHCIKPVCEP-PCQNRGSCSRP---QLCVCRSGFRGARCEE 220
Query: 314 NIDD 317
I D
Sbjct: 221 VIPD 224
Score = 33.9 bits (76), Expect = 1.9
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 5/67 (7%)
Query: 124 LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSF 181
L +PC V +G+ CP GY+ + D++EC C+ C+NT GS+
Sbjct: 588 LCAPCPPRPASPVIENGQL--ECPQGYKRLNLTHCQDINECLTLGLCKDA-ECVNTRGSY 644
Query: 182 RCQCPAG 188
C C G
Sbjct: 645 LCTCRPG 651
Score = 33.1 bits (74), Expect = 3.3
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 950 CRPGYTGAHC-QHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLV 1001
C PG+T A+ H P PC + G CS C C F G +C+ ++
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQNRGSCSRPQ---LCVCRSGFRGARCEEVI 222
Score = 32.7 bits (73), Expect = 4.3
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
PC +GG C+ G C CPA TG C P
Sbjct: 403 PCLNGGRCI---GRDECWCPANSTGKFCHLP 430
Score = 32.3 bits (72), Expect = 5.6
Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQP 282
CLNGG C+ C CP TG+FC + + +P
Sbjct: 404 CLNGGRCI---GRDECWCPANSTGKFCHLPIPQPDREP 438
Score = 31.6 bits (70), Expect = 9.5
Identities = 12/28 (42%), Positives = 16/28 (57%), Gaps = 1/28 (3%)
Query: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
PC NGGRC+ C CP +G+ C +
Sbjct: 403 PCLNGGRCIGRDE-CWCPANSTGKFCHL 429
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 240 bits (613), Expect = 1e-62
Identities = 205/701 (29%), Positives = 251/701 (35%), Gaps = 144/701 (20%)
Query: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQ---PCRAGGTCSSDGMG 755
CA E C HG C AP +C C PGW G CS A Q PC G S D
Sbjct: 105 CAQE-CVHGRCV-APN--QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 756 FHCTCPPGVQGRQCELLSPCTPN----PCEHGGRCESAP--GQLPVCSCPQGWQGPRCQQ 809
C+CP G+Q C L PCTP C+ +C AP Q C CP GP C
Sbjct: 161 GVCSCPSGLQPPNC--LQPCTPGYYGPACQFRCQCHGAPCDPQTGACFCPAERTGPSCDV 218
Query: 810 DVDE------CAGPAPCGPHGICTNLAGSFSCT-----------CHGGYTGPSCDQDIND 852
+ C C G+ GS SC C G+ GP+C Q+
Sbjct: 219 SCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECR- 277
Query: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDV------DECLSN-PCGPGTCTDHV 905
C NGG C G C C PG+ G RC + +C C P
Sbjct: 278 -----CHNGGLCDRFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARC-FP 329
Query: 906 ASFTCTCPPGYGGFHCEQDL-PDCSPS-SCFNGGTCVDGVNSFSC-------LCRPGYTG 956
A+ C C G+ G C L PD SC TC D +S SC C PG+ G
Sbjct: 330 ANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC-DREHSLSCHPMNGECSCLPGWAG 388
Query: 957 AHCQHEADPCLSRP-------CLHGGVCSAAHPGFRCTCLESFTGPQCQTL-------VD 1002
HC P CLHGGVC A C C +TGP C +L V+
Sbjct: 389 LHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPGYTGPHCASLCPPDTYGVN 446
Query: 1003 WCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCV 1062
+R C+N C C+C GW C S+PC C A QC
Sbjct: 447 CSARCSCENAIACSPIDGECVCKEGWQRGNC---SVPCPPGTWGFS------CNASCQCA 497
Query: 1063 DEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDD 1122
E + C + C P HG C+ C G G+ C
Sbjct: 498 HE--------------AVCSPQTGACTCTPGWHGAHCQ-------LPCPKGQFGEGCASR 536
Query: 1123 VDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTC 1182
D C H C + R C C G +G C ++ + G + C + GTC
Sbjct: 537 CD------CDHSDGCDPVHGR--CQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC 588
Query: 1183 VDLVGGFRCTCPPGYTGLRCEADINECRSGA----CHAAHTRDCLQDPGGGFRCLCHAGF 1238
+ G C C PG+ G C+ R G C A+ C P G C C AG+
Sbjct: 589 LPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC--HPSNG-TCYCLAGW 643
Query: 1239 SGPRCQTVLSP-------CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV-- 1289
+GP C P ++ C HGG C P G +C C + G C
Sbjct: 644 TGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG-------SCICPLGWTGHHCLEGCP 696
Query: 1290 -----ARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCR 1325
A + QC G C P C CPPG SG CR
Sbjct: 697 LGTFGANCSQPCQCGPGEKCH--PETGACVCPPGHSGAPCR 735
Score = 227 bits (579), Expect = 9e-59
Identities = 213/717 (29%), Positives = 267/717 (37%), Gaps = 178/717 (24%)
Query: 588 SQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQP 647
+Q C HG +C V C+C G G DDC+S C P
Sbjct: 106 AQECVHG-RC---VAPNQCQCVPGWRG-------DDCSSE-----------------CAP 137
Query: 648 GFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCS-- 705
G GP C+ C+ CG SC D ++G C CP G PP CL P P + P
Sbjct: 138 GMWGPQCD---KPCS---CGNNSSC-DPKSGV-CSCPSGLQPPNCLQPCTPGYYGPACQF 189
Query: 706 ----HGICYDAPGGFRCVCEPGWSGPRCSQSLARDA----CES-QPCRAGGTCSSDGMGF 756
HG D G C C +GP C S ++ C S C+ GG +
Sbjct: 190 RCQCHGAPCDPQTG-ACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS- 247
Query: 757 HCTCPPGVQGRQCELLSPCT-----PN-----PCEHGGRCESAPGQLPVCSCPQGWQGPR 806
C+CPPG G C L PC PN C +GG C+ GQ C C G+ G R
Sbjct: 248 -CSCPPGWMGTICSL--PCPEGFHGPNCSQECRCHNGGLCDRFTGQ---CRCAPGYTGDR 301
Query: 807 CQQDV------DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLN 860
C+++ +CA C P C G+ C C G+TG C + C
Sbjct: 302 CREECPVGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFTGDRCTDRL--CPDG--FY 355
Query: 861 GGSCQ-----DGVGSFSC-------SCLPGFAGPRCARDVDECLSNPCGPGTCTDH---- 904
G SCQ D S SC SCLPG+AG C + C + GPG C +H
Sbjct: 356 GLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN---ESCPQDTHGPG-CQEHCLCL 411
Query: 905 ------VASFTCTCPPGYGGFHCEQDLP------DCSPS-SCFNGGTC--VDGVNSFSCL 949
S C C PGY G HC P +CS SC N C +DG C+
Sbjct: 412 HGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG----ECV 467
Query: 950 CRPGYTGAHCQHEADP------C-LSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT--- 999
C+ G+ +C P C S C H VCS CTC + G CQ
Sbjct: 468 CKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGA--CTCTPGWHGAHCQLPCP 525
Query: 1000 ---LVDWC-SRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLC 1055
+ C SR C + C C C GW G C L C E + C
Sbjct: 526 KGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCH---LSCPEGLWGVNCSNTCTC 582
Query: 1056 QAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDP------CLAQPCQHGGTCRGYMGGYMCE 1109
+ GG C+ E+ + CVC G G C++ P C+ C + C G C
Sbjct: 583 KNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNG--TCY 638
Query: 1110 CLPGYNGDNCEDDV------DECASQ-PCQHGGSCIDLVARYLC-----------SCPPG 1151
CL G+ G +C + CA C HGG+C +C CP G
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLG 698
Query: 1152 TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINE 1208
T G C CGPG C G C CPPG++G C I E
Sbjct: 699 TFGANCS-QPCQCGPGEK------------CHPETGA--CVCPPGHSGAPCRIGIQE 740
Score = 214 bits (546), Expect = 6e-55
Identities = 218/795 (27%), Positives = 275/795 (34%), Gaps = 233/795 (29%)
Query: 298 HSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVS 357
+ C CV GW G+ CS C G G C D C
Sbjct: 118 NQCQCVPGWRGDDCSSE-------------------------CAPGMWGPQC--DKPC-- 148
Query: 358 NPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLC 417
C ++ CD P +G +C+CP G C Q
Sbjct: 149 -SCGNNSSCD--PKSG--VCSCPSGLQPPNCLQP-------------------------- 177
Query: 418 QCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDE----- 472
C GY GP C+ +C PC Q C C A TG C+V +
Sbjct: 178 -CTPGYYGPACQFRC-QCHGAPCDPQTGA--------CFCPAERTGPSCDVSCSQGTSGF 227
Query: 473 -CQSS-PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530
C S+ C NGGV + SC+CP G+ G+ C L
Sbjct: 228 FCPSTHSCQNGGVFQTPQG--SCSCPPGWMGTICSLP----------------------- 262
Query: 531 CRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECR-SQ 589
C EGF G C + +C CH+G D C CAPGYTG RC + R Q
Sbjct: 263 --CPEGFHGPNCSQ---ECR---CHNGGLCDRFTG-QCRCAPGYTGDRCREECPVGRFGQ 313
Query: 590 PCRHGGKCLDLVDKY----LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVC 645
C C + C C G TG + CT +C DG Y C
Sbjct: 314 DCAETCDCAPDARCFPANGACLCEHGFTG------------DRCTDRLCPDGF--YGLSC 359
Query: 646 QPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRC--LCPPGSLPPLCLPPSHPCAHEP 703
Q T C+ E + + P SC+ G G C CP + P C H
Sbjct: 360 QAPCT---CDRE-HSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQE------HCL 409
Query: 704 CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA----CESQPCRAGGTCSSDGMGFHCT 759
C HG A G C C PG++GP C+ D C ++ C + + C
Sbjct: 410 CLHGGVCQATSGL-CQCAPGYTGPHCASLCPPDTYGVNCSAR-CSCENAIACSPIDGECV 467
Query: 760 CPPGVQGRQCELLSPCTPNP----------CEHGGRCESAPGQLPVCSCPQGWQGPRCQ- 808
C G Q C + PC P C H C G C+C GW G CQ
Sbjct: 468 CKEGWQRGNCSV--PCPPGTWGFSCNASCQCAHEAVCSPQTG---ACTCTPGWHGAHCQL 522
Query: 809 -----QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD-------INDCDPN 856
Q + CA C C + G C C G+ G C +N +
Sbjct: 523 PCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWMGARCHLSCPEGLWGVNCSNTC 580
Query: 857 PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDEC-LSNPCGPGTCTDHV----ASFTCT 911
C NGG+C G+ C C PGF GP C R C P C +H ++ TC
Sbjct: 581 TCKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTCY 638
Query: 912 CPPGYGGFHCEQDLP------DCSPS-SCFNGGTC--VDGVNSFSCLCRPGYTGAHCQHE 962
C G+ G C Q P +C+ + C +GGTC DG SC+C G+TG H
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDG----SCICPLGWTGHH---- 690
Query: 963 ADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQ--NGGRCVQTGA 1020
CL G C G C+ QPCQ G +C
Sbjct: 691 --------CLEG--CPLGTFGANCS-------------------QPCQCGPGEKCHPETG 721
Query: 1021 YCLCPPGWSGRLCDI 1035
C+CPPG SG C I
Sbjct: 722 ACVCPPGHSGAPCRI 736
Score = 212 bits (539), Expect = 4e-54
Identities = 216/779 (27%), Positives = 276/779 (35%), Gaps = 210/779 (26%)
Query: 122 PCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVG-------EPCRHGGTC 174
P + C HG RC V P+ C C PG++G C S EC G +PC G
Sbjct: 103 PLCAQECVHG-RC-VAPNQ---CQCVPGWRGDDCSS---ECAPGMWGPQCDKPCSCGNNS 154
Query: 175 LNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCE 234
P S C CP+G P C P C PG+ G C+
Sbjct: 155 SCDPKSGVCSCPSGLQPPNCLQP--------------------------CTPGYYGPACQ 188
Query: 235 VNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE------CQLQPNACHNG 288
C G C T C CP E TG C + C ++C NG
Sbjct: 189 FRCQ-CHGAPC--------DPQTGACFCPAERTGPSCDVSCSQGTSGFFCP-STHSCQNG 238
Query: 289 GTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLL 348
G F T G SC C GW G CS + FHG C
Sbjct: 239 GV-FQTPQG-SCSCPPGWMGTICSLPCPEG-----FHGPNCSQECR-------------- 277
Query: 349 CHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIG------ANPC 402
CH +CD G+ C C PG+TG C + EC +G A C
Sbjct: 278 -----------CHNGGLCDR--FTGQ--CRCAPGYTGDRCRE---ECPVGRFGQDCAETC 319
Query: 403 EHL--GRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG----PCRNQATCLDRIGQFTC- 455
+ RC G+ C C G+TG RC + C G C+ TC DR +C
Sbjct: 320 DCAPDARCFPANGA--CLCEHGFTGDRCTDRL--CPDGFYGLSCQAPCTC-DREHSLSCH 374
Query: 456 ------ICMAGFTGTYCEVDIDECQSSP-------CVNGGVCKDRVNGFSCTCPSGFSGS 502
C+ G+ G +C + P C++GGVC+ C C G++G
Sbjct: 375 PMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQ--ATSGLCQCAPGYTGP 432
Query: 503 TCQ-------LDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH 555
C V+ A C N C P EC C EG++ C
Sbjct: 433 HCASLCPPDTYGVNCSARCSCENAIAC--SPIDGECVCKEGWQRGNCSVP---------- 480
Query: 556 HGRCVDGIASFSC--ACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTT 613
C G FSC +C + C Q C P HG C CP G
Sbjct: 481 ---CPPGTWGFSCNASCQCAHEAV-CSPQTGACTCTPGWHGAHCQ-------LPCPKGQF 529
Query: 614 GVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE------CASS-PC 666
G C D S+ C D ++ C CQ G+ G C++ E C+++ C
Sbjct: 530 GEGCASRCDCDHSDGC------DPVHGR-CQCQAGWMGARCHLSCPEGLWGVNCSNTCTC 582
Query: 667 GEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHE----PC---SHGICYDAPGGFRCV 719
GG+C+ ENG C+C PG P C P + PC +H C+ + G C
Sbjct: 583 KNGGTCLP-ENG-NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNG--TCY 638
Query: 720 CEPGWSGPRCSQSL-----ARDACESQPCRAGGTCS-SDGM--------GFHCT--CPPG 763
C GW+GP CSQ + ++ C GGTC DG G HC CP G
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLG 698
Query: 764 VQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGP 822
G C PC C G +C G C CP G G C+ + E P P
Sbjct: 699 TFGANCS--QPCQ---CGPGEKCHPETG---ACVCPPGHSGAPCRIGIQEPFTVMPTTP 749
Score = 206 bits (524), Expect = 2e-52
Identities = 191/687 (27%), Positives = 253/687 (36%), Gaps = 142/687 (20%)
Query: 495 CPSGF---SGSTCQLDVDECASTPC--RNGAKCVDQPDGYEC--RCAEGFEGTLCDR--- 544
C GF G L EC C N +CV G +C CA G G CD+
Sbjct: 90 CCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS 149
Query: 545 --NVDDCSPDP--CHHGRCVDGIASFSCA--CAPGYTGTRCESQVDECRSQPCRHGGKCL 598
N C P C C G+ +C C PGY G C+ + +C PC
Sbjct: 150 CGNNSSCDPKSGVCS---CPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDP----- 200
Query: 599 DLVDKYLCRCPSGTTGVNCEVNIDDCASN---PCTFGVCRDGINRY---DCVCQPGFTGP 652
C CP+ TG +C+V+ S P T G+ + C C PG+ G
Sbjct: 201 ---QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT 257
Query: 653 LCNVEINECASSP-------CGEGG---------SCVDGENGFRCL--CPPGSLPPLCLP 694
+C++ E P C GG C G G RC CP G C
Sbjct: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDC-- 315
Query: 695 PSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTC----- 749
+ C P + C+ A G C+CE G++G RC+ L D C+A TC
Sbjct: 316 -AETCDCAPDAR--CFPANGA--CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHS 370
Query: 750 -SSDGMGFHCTCPPGVQGRQCELLSP-CTPNP-------CEHGGRCESAPGQLPVCSCPQ 800
S M C+C PG G C P T P C HGG C++ G +C C
Sbjct: 371 LSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG---LCQCAP 427
Query: 801 GWQGPRCQQDVD------ECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
G+ GP C C+ C C+ + G C C G+ +C C
Sbjct: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGNCSV---PCP 482
Query: 855 PN----------PCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCT-- 902
P C + C G +C+C PG+ G C C G G +
Sbjct: 483 PGTWGFSCNASCQCAHEAVCSPQTG--ACTCTPGWHGAHCQL---PCPKGQFGEGCASRC 537
Query: 903 --DH-----VASFTCTCPPGYGGFHCEQDLPD------CSPS-SCFNGGTCVDGVNSFSC 948
DH C C G+ G C P+ CS + +C NGGTC+ + +C
Sbjct: 538 DCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLP--ENGNC 595
Query: 949 LCRPGYTGAHCQHEADP------CLSRPCLHGGVCSAAHP-GFRCTCLESFTGPQCQTLV 1001
+C PG+ G CQ P C+ C + C HP C CL +TGP C
Sbjct: 596 VCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFC---HPSNGTCYCLAGWTGPDCSQPC 652
Query: 1002 ---DW---CSRQ-PCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQL 1054
W C++ C +GG C C+CP GW+G C + P G Q
Sbjct: 653 PPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHC-LEGCP----LGTFGANCSQP 707
Query: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHC 1081
CQ G + CVCP G +G+ C
Sbjct: 708 CQCGPGEKCHPETGACVCPPGHSGAPC 734
Score = 197 bits (502), Expect = 8e-50
Identities = 188/691 (27%), Positives = 240/691 (34%), Gaps = 190/691 (27%)
Query: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCP-------------PGWVGERCQLEDPC 82
PG P C C N C + C CP PG+ G CQ C
Sbjct: 137 PGMWGPQCDKPCSCGNNSSCDP---KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC 193
Query: 83 HSGPC---------------------AGRGV----------CQSSVVAGTARFSCRCPRG 111
H PC +G CQ+ V T + SC CP G
Sbjct: 194 HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPG 253
Query: 112 FRGPDCSLPDP--CLSSPCAHGARC-SVGPDGRFL--CSCPPGYQGRSCRSDVDECRVGE 166
+ G CSLP P C+ RC + G RF C C PGY G CR + R G+
Sbjct: 254 WMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQ 313
Query: 167 PCRHGGTCLNT----PGSFRCQCPAGYTGPLCENPAVP------CAPSPCRNGGTCRQSG 216
C C P + C C G+TG C + P +PC TC +
Sbjct: 314 DCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPC----TCDREH 369
Query: 217 DLTY-----DCACLPGFEGQNC------EVNVDDCPGH-RCLNGGTCVDGVNTYNCQCPP 264
L+ +C+CLPG+ G +C + + C H CL+GG C + CQC P
Sbjct: 370 SLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCAP 427
Query: 265 EWTGQFCTEDVDECQLQPN-----ACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCA 319
+TG C N +C N C G CVC GW +CS
Sbjct: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDG--ECVCKEGWQRGNCS------- 478
Query: 320 TAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTC 379
CP G G C+ S C +A+C +P G CTC
Sbjct: 479 ------------------VPCPPGTWGFSCN-----ASCQCAHEAVC--SPQTG--ACTC 511
Query: 380 PPGFTGGACDQDVDECSIGAN-----PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNE 434
PG+ G C + G C+H C G CQC G+ G RC E
Sbjct: 512 TPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWMGARCHLSCPE 569
Query: 435 CLSG-------PCRNQATCLDRIGQFTCICMAGFTGTYCEVDID------ECQSSPCVNG 481
L G C+N TCL G C+C GF G C+ C C N
Sbjct: 570 GLWGVNCSNTCTCKNGGTCLPENG--NCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANH 627
Query: 482 GVCKDRVNGFSCTCPSGFSGSTCQLDV------DECAST-PCRNGAKCVDQPDGYECRCA 534
C NG +C C +G++G C + CA T C +G C P C C
Sbjct: 628 SFCHPS-NG-TCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTC--HPQDGSCICP 683
Query: 535 EGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCR-- 592
G+ G HH C++G C G G C SQPC+
Sbjct: 684 LGWTG---------------HH--CLEG-------CPLGTFGANC--------SQPCQCG 711
Query: 593 HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD 623
G KC + C CP G +G C + I +
Sbjct: 712 PGEKCHP--ETGACVCPPGHSGAPCRIGIQE 740
Score = 197 bits (501), Expect = 1e-49
Identities = 194/705 (27%), Positives = 248/705 (35%), Gaps = 144/705 (20%)
Query: 37 GAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP-CAGRGVCQ 94
G P C C +G RC P++ C C PGW G+ C E P GP C C
Sbjct: 99 GFCVPLC--AQECVHG-RCVA-PNQ---CQCVPGWRGDDCSSECAPGMWGPQCDKPCSCG 151
Query: 95 SSVVAGTARFSCRCPRGFRGPDCSLP------DPCLSSPC-AHGARCSVGPDGRFLCSCP 147
++ C CP G + P+C P P C HGA C C CP
Sbjct: 152 NNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA---CFCP 208
Query: 148 PGYQGRSCRSDVDE------CRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPC 201
G SC + C C++GG GS C CP G+ G +C P
Sbjct: 209 AERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS--CSCPPGWMGTICSLPCPEG 266
Query: 202 APSP-------CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP----GHRCLNGGT 250
P C NGG C + T C C PG+ G C ++CP G C
Sbjct: 267 FHGPNCSQECRCHNGGLCDR---FTGQCRCAPGYTGDRCR---EECPVGRFGQDCAETCD 320
Query: 251 CVDGVNTY----NCQCPPEWTGQFCTEDVDECQLQPNACHNGGTC--FNTLGGH----SC 300
C + C C +TG CT+ + +C TC ++L H C
Sbjct: 321 CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 380
Query: 301 VCVNGWTG----ESCSQNIDDCAT---AVCFHGATCHDRVASFYCACPMGKTG------- 346
C+ GW G ESC Q+ +C HG C + S C C G TG
Sbjct: 381 SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLC 438
Query: 347 ----------LLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECS 396
C ++A +P + +C G CPPG G +C+
Sbjct: 439 PPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQ--- 495
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGP-CRNQATCLDRIG---- 451
C H C G+ C C G+ G C+ + G C ++ C G
Sbjct: 496 -----CAHEAVCSPQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPV 548
Query: 452 QFTCICMAGFTGTYCEVDIDE------CQSS-PCVNGGVCKDRVNGFSCTCPSGFSGSTC 504
C C AG+ G C + E C ++ C NGG C NG +C C GF G +C
Sbjct: 549 HGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPE-NG-NCVCAPGFRGPSC 606
Query: 505 QLDVD------ECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR 558
Q C C N + C P C C G+ G DCS PC G
Sbjct: 607 QRSCQPGRYGKRCVPCKCANHSFC--HPSNGTCYCLAGWTG-------PDCS-QPCPPGH 656
Query: 559 CVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCE 618
+ A +C C G T C Q C G CL+ CP GT G NC
Sbjct: 657 WGENCAQ-TCQCHHGGT---CHPQDGSCICPLGWTGHHCLE-------GCPLGTFGANC- 704
Query: 619 VNIDDCASNPCTFG---VCRDGINRYDCVCQPGFTGPLCNVEINE 660
S PC G C CVC PG +G C + I E
Sbjct: 705 -------SQPCQCGPGEKCHPETGA--CVCPPGHSGAPCRIGIQE 740
Score = 192 bits (489), Expect = 2e-48
Identities = 180/644 (27%), Positives = 212/644 (32%), Gaps = 155/644 (24%)
Query: 878 GFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL------PDCS-P 930
GF P CA+ EC+ C VA C C PG+ G C + P C P
Sbjct: 99 GFCVPLCAQ---ECVHGRC--------VAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKP 147
Query: 931 SSCFNGGTC---------VDGVNSFSCL--CRPGYTGAHCQHEADPCLSRPCLHGGVCSA 979
SC N +C G+ +CL C PGY G CQ HG C
Sbjct: 148 CSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQ-------CHGAPCDP 200
Query: 980 AHPGFRCTCLESFTGPQCQTLVD------WC-SRQPCQNGGRCVQTGAYCLCPPGWSGRL 1032
C C TGP C +C S CQNGG C CPPGW G +
Sbjct: 201 QTGA--CFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTI 258
Query: 1033 CDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV------D 1086
C SLPC E E C GG C + + C C G TG C +E
Sbjct: 259 C---SLPCPEGFHGPNCSQECRCHNGGLC--DRFTGQCRCAPGYTGDRCREECPVGRFGQ 313
Query: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDV------DECASQPC----QHGGS 1136
C A+ C R + C C G+ GD C D + PC +H S
Sbjct: 314 DC-AETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLS 372
Query: 1137 CIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1196
C + CSC PG G+ C + GP CLH G C G C C PG
Sbjct: 373 CHPMNGE--CSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSG--LCQCAPG 428
Query: 1197 YTGLRCEA-------DIN--------------------ECRSG----------------- 1212
YTG C + +N C+ G
Sbjct: 429 YTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGF 488
Query: 1213 ----ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL------SPCESQ-PCQHGGQC 1261
+C AH C G C C G+ G CQ C S+ C H C
Sbjct: 489 SCNASCQCAHEAVCSPQTGA---CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545
Query: 1262 RPSPG----PGGGLTFTCH--CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCAC 1315
P G G + CH C + WG C C G C P C C
Sbjct: 546 DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC------TCKNGGTC--LPENGNCVC 597
Query: 1316 PPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAP 1375
PG GPSC+ PG C C + C P+ C C GWTGP C P
Sbjct: 598 APGFRGPSCQR--SCQPGRYGKRCVPCKCANHSFCHPSN----GTCYCLAGWTGPDCSQP 651
Query: 1376 AAAPEVSEEPRCPRAACQAKRGD--QRCDRECNSPGCGWDGGDC 1417
E C + CQ G D C P GW G C
Sbjct: 652 CPPGHWGE--NCAQ-TCQCHHGGTCHPQDGSCICP-LGWTGHHC 691
Score = 165 bits (418), Expect = 4e-40
Identities = 167/579 (28%), Positives = 199/579 (34%), Gaps = 123/579 (21%)
Query: 1013 GRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVC 1072
GRCV C C PGW G C P G + ++ C G + S C C
Sbjct: 112 GRCVAPNQ-CQCVPGWRGDDCSSECAP-----GMWGPQCDKPCSCGNNSSCDPKSGVCSC 165
Query: 1073 PEGRTGSHCEQEVDPCLAQP-----CQ-HGGTCRGYMGGYMCECLPGYNGDNCEDDVDEC 1126
P G +C Q P P CQ HG C G C C G +C+ +
Sbjct: 166 PSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGA--CFCPAERTGPSCDVSCSQG 223
Query: 1127 AS-------QPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
S CQ+GG + + CSCPPG +G +C + + GP RC +
Sbjct: 224 TSGFFCPSTHSCQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNG 281
Query: 1180 GTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQD----PGGGFRCLCH 1235
G C G +C C PGYTG RC + R G A T DC D P G CLC
Sbjct: 282 GLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQ-DCAETCDCAPDARCFPANG-ACLCE 337
Query: 1236 AGFSGPRCQTVLSP-------CESQPC----QHGGQCRPSPG-----PG-GGLTFTCHCA 1278
GF+G RC L P C++ PC +H C P G PG GL C
Sbjct: 338 HGFTGDRCTDRLCPDGFYGLSCQA-PCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCP 396
Query: 1279 QPFWGPRCERVARSCRELQCPVGVPCQQTP---------RGPRCA--CPPGLSGPSCR-- 1325
Q GP C+ C G CQ T GP CA CPP G +C
Sbjct: 397 QDTHGPGCQ------EHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSAR 450
Query: 1326 ---------------------------SFPGSPPGASNASC-AAAPCLHGGSCRPAPLAP 1357
S P PPG SC A+ C H C P A
Sbjct: 451 CSCENAIACSPIDGECVCKEGWQRGNCSVP-CPPGTWGFSCNASCQCAHEAVCSPQTGA- 508
Query: 1358 FFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDC 1417
C C GW G C+ P + E R C G C GW G C
Sbjct: 509 ---CTCTPGWHGAHCQLPCPKGQFG-EGCASRCDCDHSDGCDPVHGRCQCQ-AGWMGARC 563
Query: 1418 SLSVGDP-W-----RQCEALQ---CWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCN 1468
LS + W C C N C P P+C C G + C
Sbjct: 564 HLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSC---QRSCQPGRYGKRCV 620
Query: 1469 PVYEKYCADHFADGRCDQGCNTEEC--GWDGLDCASEVP 1505
P CA+H C T C GW G DC+ P
Sbjct: 621 PC---KCANH---SFCHPSNGTCYCLAGWTGPDCSQPCP 653
Score = 72.8 bits (177), Expect = 4e-12
Identities = 57/183 (31%), Positives = 69/183 (37%), Gaps = 30/183 (16%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGV---CQSSVVA 99
C + C NGG C LP C+C PG+ G CQ C G R V C +
Sbjct: 576 CSNTCTCKNGGTC--LPEN-GNCVCAPGFRGPSCQRS--CQPGRYGKRCVPCKCANHSFC 630
Query: 100 GTARFSCRCPRGFRGPDCSLPDP--------CLSSPCAHGARCSVGPDGRFLC------- 144
+ +C C G+ GPDCS P P + C HG C DG +C
Sbjct: 631 HPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHP-QDGSCICPLGWTGH 689
Query: 145 ----SCPPGYQGRSCRSDVDECRVGEPCR-HGGTCLNTPGSFRCQCPAGYTGPLCENPAV 199
CP G G +C S +C GE C G C+ PG C G P P
Sbjct: 690 HCLEGCPLGTFGANC-SQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTT 748
Query: 200 PCA 202
P A
Sbjct: 749 PVA 751
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 238 bits (608), Expect = 4e-62
Identities = 128/336 (38%), Positives = 172/336 (51%), Gaps = 29/336 (8%)
Query: 378 TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLS 437
+C PG+TG C Q + C G + E G C C C G+ G C NEC+
Sbjct: 207 SCLPGWTGEYCQQPI--CLSGCH--EQNGYCSKPAE---CLCRPGWQGRLC----NECIP 255
Query: 438 GPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC-QSSPCVNGGVCKDR-VNGFSCTC 495
TC + C C G+ G +C+ D++ C SPC NG C + ++CTC
Sbjct: 256 HNGCRHGTCST---PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTC 312
Query: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH 555
G++G C+L++ EC S PCRNG C DQ DGY C C G+ G C+ + C+ PC
Sbjct: 313 RPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCF 372
Query: 556 HG---RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGT 612
+G R + A+++C C P +TG+ CE +VD C S PC +GG+CL+ +CRC G
Sbjct: 373 NGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGF 432
Query: 613 TGVNCEVNIDDCASNPCTF-GVCRDGINRYDCVCQPGFTGPLCNV--EINECASSPCGEG 669
TG CE+++ DCA NPC G C D N C C GF+G C V I+ CASSPC
Sbjct: 433 TGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNR 492
Query: 670 GSCVD--GENGFRCLCPPGSLPPLC-----LPPSHP 698
+C + F C CP G + C LPPS P
Sbjct: 493 ATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPPSFP 528
Score = 225 bits (574), Expect = 3e-58
Identities = 132/376 (35%), Positives = 178/376 (47%), Gaps = 39/376 (10%)
Query: 180 SFRCQCPAGYTGPLCENPAVPCAPSPCRNGG-TCRQSGDLTYDCACLPGFEGQNCEVNVD 238
S+R C Y G C C G C+ G+L+ CLPG+ G+ C+ +
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLS----CLPGWTGEYCQQPI- 221
Query: 239 DCPGHRCLNGGTCVDGV--NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLG 296
CL+G +G C C P W G+ C E + N C +G TC
Sbjct: 222 ------CLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPH-----NGCRHG-TCSTPW- 268
Query: 297 GHSCVCVNGWTGESCSQNIDDCAT-AVCFHGATCHDR-VASFYCACPMGKTGLLCHLD-D 353
C C GW G C Q+++ C + C +GATC + S+ C C G TG+ C L+
Sbjct: 269 --QCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELS 326
Query: 354 ACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCV--NT 411
C SNPC C C CPPG+ G C+ C+ +PC + G C N
Sbjct: 327 ECDSNPCRNGGSCKDQEDGYH--CLCPPGYYGLHCEHSTLSCA--DSPCFNGGSCRERNQ 382
Query: 412 QGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDID 471
++ C+C +TG CE V+ C S PC N CL+R C C GFTGTYCE+ +
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVS 442
Query: 472 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQL--DVDECASTPCRNGAKCVD--QPD 527
+C +PC +GG C D NG CTCP+GFSG C++ +D CAS+PC N A C D
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTD 502
Query: 528 GYECRCAEGFEGTLCD 543
+ C C GF G+ C+
Sbjct: 503 TFVCNCPYGFVGSRCE 518
Score = 222 bits (566), Expect = 3e-57
Identities = 120/316 (37%), Positives = 159/316 (50%), Gaps = 25/316 (7%)
Query: 41 PPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAG 100
P CL G NG S+ A CLC PGW G C P H+G G C +
Sbjct: 220 PICLSGCHEQNG-----YCSKPAECLCRPGWQGRLCNECIP-HNG--CRHGTCSTP---- 267
Query: 101 TARFSCRCPRGFRGPDCSLP-DPCLS-SPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSD 158
+ C C G+ G C + C SPC +GA CS + C+C PGY G C +
Sbjct: 268 ---WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELE 324
Query: 159 VDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGD- 217
+ EC PCR+GG+C + + C CP GY G CE+ + CA SPC NGG+CR+
Sbjct: 325 LSECD-SNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQG 383
Query: 218 LTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Y C C P F G NCE VD C + C NGG C++ + C+C P +TG +C V +
Sbjct: 384 ANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSD 443
Query: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS--QNIDDCATAVCFHGATCHDRVA- 334
C P C +GGTC + G C C G++G C +ID CA++ CF+ ATC+ ++
Sbjct: 444 CARNP--CAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501
Query: 335 -SFYCACPMGKTGLLC 349
+F C CP G G C
Sbjct: 502 DTFVCNCPYGFVGSRC 517
Score = 220 bits (561), Expect = 1e-56
Identities = 134/390 (34%), Positives = 181/390 (46%), Gaps = 49/390 (12%)
Query: 827 TNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQ-DGVGSFSCSCLPGFAGPRCA 885
T L S+ C Y G +C + N CQ DG + SCLPG+ G C
Sbjct: 165 TRLRYSYRVICSDNYYGDNCSRLCKK--RNDHFGHYVCQPDG----NLSCLPGWTGEYCQ 218
Query: 886 RDVDECLSNPCGP--GTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGV 943
+ + CLS C G C+ C C PG+ G C + C P + GTC
Sbjct: 219 QPI--CLSG-CHEQNGYCSKPAE---CLCRPGWQGRLCNE----CIPHNGCRHGTCS--- 265
Query: 944 NSFSCLCRPGYTGAHCQHEADPCLSR-PCLHGGVCS-AAHPGFRCTCLESFTGPQCQTLV 1001
+ C C G+ G C + + C PC +G CS + + CTC +TG C+ +
Sbjct: 266 TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELEL 325
Query: 1002 DWCSRQPCQNGGRCV--QTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
C PC+NGG C + G +CLCPPG+ G C+ +L C ++ C GG
Sbjct: 326 SECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP----------CFNGG 375
Query: 1060 QCVDED--SSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGD 1117
C + + +++ C CP TGS+CE++VD C + PC +GG C MC C PG+ G
Sbjct: 376 SCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGT 435
Query: 1118 NCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINE--DDCGPGPPLDSGPR 1175
CE V +CA PC HGG+C DL +C+CP G G CE+ D C P
Sbjct: 436 YCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSP------- 488
Query: 1176 CLHNGTC-VDL-VGGFRCTCPPGYTGLRCE 1203
C + TC DL F C CP G+ G RCE
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 208 bits (529), Expect = 6e-53
Identities = 132/389 (33%), Positives = 181/389 (46%), Gaps = 38/389 (9%)
Query: 103 RFSCR--CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVD 160
R+S R C + G +CS H PDG SC PG+ G C+ +
Sbjct: 168 RYSYRVICSDNYYGDNCSR---LCKKRNDHFGHYVCQPDGNL--SCLPGWTGEYCQQPI- 221
Query: 161 ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAP-SPCRNGGTCRQSGDLT 219
C G C + P C C G+ G LC C P + CR+G TC
Sbjct: 222 -CLSG--CHEQNGYCSKPAE--CLCRPGWQGRLCNE----CIPHNGCRHG-TC----STP 267
Query: 220 YDCACLPGFEGQNCEVNVDDCPGHR-CLNGGTCVD-GVNTYNCQCPPEWTGQFCTEDVDE 277
+ C C G+ G C+ +++ C H C NG TC + G +Y C C P +TG C ++ E
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSE 327
Query: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV--AS 335
C P C NGG+C + G+ C+C G+ G C + CA + CF+G +C +R A+
Sbjct: 328 CDSNP--CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGAN 385
Query: 336 FYCACPMGKTGLLCHLD-DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDE 394
+ C CP TG C D C SNPC C + +C C PGFTG C+ V +
Sbjct: 386 YACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPS--RMCRCRPGFTGTYCELHVSD 443
Query: 395 CSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCE--TDVNECLSGPCRNQATCLDRIGQ 452
C+ NPC H G C + + +C C G++G RCE T ++ C S PC N+ATC +
Sbjct: 444 CA--RNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLST 501
Query: 453 --FTCICMAGFTGTYCEVDIDECQSSPCV 479
F C C GF G+ CE + S P V
Sbjct: 502 DTFVCNCPYGFVGSRCEFPVGLPPSFPWV 530
Score = 207 bits (528), Expect = 7e-53
Identities = 126/379 (33%), Positives = 170/379 (44%), Gaps = 51/379 (13%)
Query: 565 SFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCR------CPSGTTGVNCE 618
S+ C+ Y G C S+ C+ K D Y+C+ C G TG C+
Sbjct: 170 SYRVICSDNYYGDNC--------SRLCK---KRNDHFGHYVCQPDGNLSCLPGWTGEYCQ 218
Query: 619 VNIDDCASNPCTFGVCRDGINRY-----DCVCQPGFTGPLCNVEINECASSPCGEGGSCV 673
P C + N Y +C+C+PG+ G LCN EC G+C
Sbjct: 219 --------QPICLSGCHEQ-NGYCSKPAECLCRPGWQGRLCN----ECIPHNGCRHGTC- 264
Query: 674 DGENGFRCLCPPGSLPPLCLPPSHPCAHE-PCSHGICYDAPG--GFRCVCEPGWSGPRCS 730
++C C G C + C H PC +G G + C C PG++G C
Sbjct: 265 --STPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 731 QSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLS-PCTPNPCEHGGRC-ES 788
L+ C+S PCR GG+C G+HC CPPG G CE + C +PC +GG C E
Sbjct: 323 LELSE--CDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRER 380
Query: 789 APGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ 848
G C CP + G C++ VD C PC G C N S C C G+TG C+
Sbjct: 381 NQGANYACECPPNFTGSNCEKKVDRCTSN-PCANGGQCLNRGPSRMCRCRPGFTGTYCEL 439
Query: 849 DINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRC--ARDVDECLSNPC-GPGTCTDHV 905
++DC NPC +GG+C D C+C GF+G RC +D C S+PC TC +
Sbjct: 440 HVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDL 499
Query: 906 A--SFTCTCPPGYGGFHCE 922
+ +F C CP G+ G CE
Sbjct: 500 STDTFVCNCPYGFVGSRCE 518
Score = 206 bits (523), Expect = 3e-52
Identities = 121/338 (35%), Positives = 163/338 (48%), Gaps = 31/338 (9%)
Query: 523 VDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH--HGRCVDGIASFSCACAPGYTGTRCE 580
V QPDG C G+ G C + + CH +G C C C PG+ G C
Sbjct: 199 VCQPDG-NLSCLPGWTGEYCQQPI---CLSGCHEQNGYCSKPA---ECLCRPGWQGRLCN 251
Query: 581 SQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN-PCTFGVC--RDG 637
+ CRHG + C C G G+ C+ +++ C + PC G G
Sbjct: 252 ECIPH---NGCRHG----TCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSG 304
Query: 638 INRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSH 697
Y C C+PG+TG C +E++EC S+PC GGSC D E+G+ CLCPPG C +
Sbjct: 305 QRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTL 364
Query: 698 PCAHEPC-SHGICYDAPGG--FRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGM 754
CA PC + G C + G + C C P ++G C + + D C S PC GG C + G
Sbjct: 365 SCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKV--DRCTSNPCANGGQCLNRGP 422
Query: 755 GFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ--QDV 811
C C PG G CEL +S C NPC HGG C L +C+CP G+ G RC+ +
Sbjct: 423 SRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGL-MCTCPAGFSGRRCEVRTSI 481
Query: 812 DECAGPAPCGPHGIC-TNLA-GSFSCTCHGGYTGPSCD 847
D CA +PC C T+L+ +F C C G+ G C+
Sbjct: 482 DACAS-SPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 195 bits (495), Expect = 5e-49
Identities = 133/397 (33%), Positives = 169/397 (42%), Gaps = 50/397 (12%)
Query: 945 SFSCLCRPGYTGAHCQHEADPCLSRPCLHGG-VCSAAHPGFRCTCLESFTGPQCQTLVDW 1003
S+ +C Y G +C C R G VC P +CL +TG CQ +
Sbjct: 170 SYRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQ---PDGNLSCLPGWTGEYCQQPI-- 221
Query: 1004 CSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVD 1063
C + G C + A CLC PGW GRLC+ E G R G C
Sbjct: 222 CLSGCHEQNGYCSKP-AECLCRPGWQGRLCN-------ECIPHNGCR-------HGTC-- 264
Query: 1064 EDSSHYCVCPEGRTGSHCEQEVDPCLAQ-PCQHGGTCRGY-MGGYMCECLPGYNGDNCED 1121
+ C C EG G C+Q+++ C PC++G TC Y C C PGY G +CE
Sbjct: 265 -STPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCEL 323
Query: 1122 DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGT 1181
++ EC S PC++GGSC D Y C CPPG G+ CE + C P C + G+
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSP-------CFNGGS 376
Query: 1182 CVDLVGG--FRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFS 1239
C + G + C CPP +TG CE ++ C S C A+ CL + G C C GF+
Sbjct: 377 CRERNQGANYACECPPNFTGSNCEKKVDRCTSNPC--ANGGQCL-NRGPSRMCRCRPGFT 433
Query: 1240 GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCE--RVARSCRELQ 1297
G C+ +S C PC HGG C GL C C F G RCE +C
Sbjct: 434 GTYCELHVSDCARNPCAHGGTCHDLEN---GLM--CTCPAGFSGRRCEVRTSIDACASSP 488
Query: 1298 CPVGVPCQQTPRGPR--CACPPGLSGPSCRSFPGSPP 1332
C C C CP G G C G PP
Sbjct: 489 CFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLPP 525
Score = 191 bits (485), Expect = 7e-48
Identities = 121/400 (30%), Positives = 165/400 (41%), Gaps = 50/400 (12%)
Query: 984 FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREA 1043
+R C +++ G C L C ++ G Q C PGW+G C
Sbjct: 171 YRVICSDNYYGDNCSRL---CKKRNDHFGHYVCQPDGNLSCLPGWTGEYC---------- 217
Query: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQP-CQHGGTCRGY 1102
Q + L + G C C+C G G C + C+ C+HG TC
Sbjct: 218 --QQPICLSGCHEQNGYC---SKPAECLCRPGWQGRLCNE----CIPHNGCRHG-TCST- 266
Query: 1103 MGGYMCECLPGYNGDNCEDDVDECASQ-PCQHGGSCIDLVAR-YLCSCPPGTLGVLCEIN 1160
+ C C G+ G C+ D++ C PC++G +C + R Y C+C PG GV CE+
Sbjct: 267 --PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELE 324
Query: 1161 EDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGAC-HAAHT 1219
+C DS P C + G+C D G+ C CPPGY GL CE C C +
Sbjct: 325 LSEC------DSNP-CRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSC 377
Query: 1220 RDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQ 1279
R+ ++ G + C C F+G C+ + C S PC +GGQC G + C C
Sbjct: 378 RE--RNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCL-----NRGPSRMCRCRP 430
Query: 1280 PFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASC 1339
F G CE C C G C G C CP G SG C S +C
Sbjct: 431 GFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCE------VRTSIDAC 484
Query: 1340 AAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAP 1379
A++PC + +C F C C G+ G RCE P P
Sbjct: 485 ASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLP 524
Score = 166 bits (421), Expect = 2e-40
Identities = 107/354 (30%), Positives = 147/354 (41%), Gaps = 38/354 (10%)
Query: 1072 CPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPC 1131
C G TG +C+Q + CL+ + G C C C PG+ G C + + C
Sbjct: 208 CLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQGRLCNECIPH---NGC 259
Query: 1132 QHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC 1191
+HG +C + C+C G G+ C+ + + C P +G C ++G + C
Sbjct: 260 RHG-TCS---TPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQ-----RSYTC 310
Query: 1192 TCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCE 1251
TC PGYTG+ CE +++EC S C + +D G+ CLC G+ G C+ C
Sbjct: 311 TCRPGYTGVDCELELSECDSNPCRNGGS---CKDQEDGYHCLCPPGYYGLHCEHSTLSCA 367
Query: 1252 SQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGP 1311
PC +GG CR G + C C F G CE+ C C G C
Sbjct: 368 DSPCFNGGSCRER---NQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSR 424
Query: 1312 RCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPR 1371
C C PG +G C + CA PC HGG+C L C C G++G R
Sbjct: 425 MCRCRPGFTGTYCELHV--------SDCARNPCAHGGTCHD--LENGLMCTCPAGFSGRR 474
Query: 1372 CEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR-ECNSPGCGWDGGDCSLSVGDP 1424
CE + + P RA C D D CN P G+ G C VG P
Sbjct: 475 CEVRTSIDACASSPCFNRATCYT---DLSTDTFVCNCP-YGFVGSRCEFPVGLP 524
Score = 113 bits (283), Expect = 2e-24
Identities = 65/162 (40%), Positives = 82/162 (50%), Gaps = 14/162 (8%)
Query: 43 CLDGSPCANGGRCTQL-PSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAG 100
C D SPC NGG C + AC CPP + G C+ + D C S PCA G C + G
Sbjct: 366 CAD-SPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNR---G 421
Query: 101 TARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSC--RS 157
+R CRC GF G C L C +PCAHG C +G +C+CP G+ GR C R+
Sbjct: 422 PSRM-CRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENG-LMCTCPAGFSGRRCEVRT 479
Query: 158 DVDECRVGEPCRHGGTCLN--TPGSFRCQCPAGYTGPLCENP 197
+D C PC + TC + +F C CP G+ G CE P
Sbjct: 480 SIDAC-ASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFP 520
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 227 bits (578), Expect = 1e-58
Identities = 237/870 (27%), Positives = 341/870 (39%), Gaps = 146/870 (16%)
Query: 469 DIDECQSSPCVNG-GVCKDRVNGFSCTCPSGFSGSTCQ---LDVDECASTP--CRNGAKC 522
+I+EC +P + G G C + ++C C G+ S Q +D+DEC C G +C
Sbjct: 874 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RC 932
Query: 523 VDQPDGYECRCAEGF----EGTLCDRNVDDC-SPDPCHHGRCVDGIASFSCA-CAPGYTG 576
+ + C C GF EGT C +VD+C PD C G CV+ + +F C C GY
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 991
Query: 577 T---RCESQVDECRSQPCRHGGKCLDLVDKYLC-RCPSGTTGVNCE-VNIDDCAS-NPCT 630
T RCE +DEC + +C++ Y C C G G N + +++D+C N C
Sbjct: 992 TQRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA 1050
Query: 631 FGVCRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPG- 686
G C + Y C C G+T + +I+EC G C + E FRC C G
Sbjct: 1051 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 1110
Query: 687 --SLPPLCLPPSHPCAHEP-CSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE 739
S C H C+HG C + G F+CVC+ G+ G C + E
Sbjct: 1111 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INECLE 1168
Query: 740 SQPCRAGGTCSSDGMGFHCTCPPGVQ---GRQCELLSPCT-PNPCEHGGRCESAPGQLPV 795
+ G C + + CTCP G Q + C+ ++ C P C G C + G
Sbjct: 1169 DKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH- 1227
Query: 796 CSCPQGWQ----GPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ--- 848
C C QG+ G C+ D+DEC C HG C N AGSF C C+ G+ P Q
Sbjct: 1228 CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 1286
Query: 849 DINDCDPNPCLNGGS-CQDGVGSFSCSC---------LPGFAGPRCARDVD--------- 889
D+N+C+ + G + C++ GSF C C + G R + D+D
Sbjct: 1287 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1346
Query: 890 --ECLSNPCGPGTCTD----HVASFTCTCPPGYG-GFHCEQDLPDCSPSSCFNGGTCVDG 942
EC N C + +V C C G G G +CE + C V G
Sbjct: 1347 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCE--IFPCP----------VLG 1394
Query: 943 VNSFSCLCRPG-----------YTGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCL 989
F+ +C G G +AD CL + G C PG+ C C
Sbjct: 1395 TAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCK 1454
Query: 990 E-SFTGP---QCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREA 1043
+ ++ P QC + D C G+CV T G+Y C C + R + E+
Sbjct: 1455 QGTYYDPVKLQCFDM-DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAES 1513
Query: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM 1103
QI E+ C + S Y VC G CL G
Sbjct: 1514 NEQI----EETDVYQDLCWEHLSDEY-VCSRPLVGKQTTYTECCCL----------YGEA 1558
Query: 1104 GGYMCECLPGYNGDNCED--DVDECASQPCQHGGSCIDLVARYLCSCPP-----GTLGVL 1156
G C P + D+ ++ + + +D +Y P L
Sbjct: 1559 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1618
Query: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY---TGLRCEADINEC---- 1209
E+ ++CG + +G NG CV + G+ C C GY T D+NEC
Sbjct: 1619 EELQAEECG----ILNG---CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1671
Query: 1210 -RSGACHAAHTRDCLQDPGGGFRCLCHAGF 1238
R C A C+ + G ++CLC G+
Sbjct: 1672 NRMSLCKNA---KCI-NTDGSYKCLCLPGY 1697
Score = 207 bits (527), Expect = 1e-52
Identities = 278/1059 (26%), Positives = 387/1059 (36%), Gaps = 249/1059 (23%)
Query: 16 SPPPPPPPVRALPLLLLLA----GPGAAAP-----------PCLDGSPCA-NGGRCTQLP 59
S PPP P + P+ L GPG A P P LD G+ P
Sbjct: 768 STHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSP 827
Query: 60 SREAACLCP--PGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
L P PG V E+ P P A S V+A T +C
Sbjct: 828 GISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSA-SQVIAPTQVTEIN--------EC 878
Query: 118 SL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGG 172
++ PD C + C + R+ C C GY Q R C D+DEC + G
Sbjct: 879 TVNPDICGAGHC-------INLPVRYTCICYEGYRFSEQQRKC-VDIDECTQVQHLCSQG 930
Query: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
C NT GSF C CPAG+ + EG N
Sbjct: 931 RCENTEGSFLCICPAGF-----------------------------------MASEEGTN 955
Query: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQ-CPPEW--TGQFCTEDVDECQLQPNACHNGG 289
C ++VD+C G CV+ V + C+ C + T + ED+DEC L P+ C +
Sbjct: 956 C-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPD-E 1012
Query: 290 TCFNTLGGHSCV-CV---NGWTGESCSQNIDDCATA-VCFHGATCHDRVASFYCACPMGK 344
C N+ G + CV C GW G+ ++D+C VC +G C + S+ C+C G
Sbjct: 1013 QCVNSPGSYQCVPCTEGFRGWNGQCL--DVDECLEPNVCANG-DCSNLEGSYMCSCHKGY 1069
Query: 345 TGLLCH-----LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD---QDVDECS 396
T H +D+ N C +T G CTC G+ A +D+DEC
Sbjct: 1070 TRTPDHKHCRDIDECQQGNLCVNGQCKNT---EGSFRCTCGQGYQLSAAKDQCEDIDECQ 1126
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECL--SGPCRNQATCLDRI 450
+ C H G+C NT+GSF C C +GY G CE D+NECL C+ + C++
Sbjct: 1127 -HRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLEDKSVCQ-RGDCINTA 1182
Query: 451 GQFTCICMAGF---TGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS----GS 502
G + C C GF C+ DI+EC+ C G C + F C C GFS G
Sbjct: 1183 GSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 1241
Query: 503 TCQLDVDECA-STPCRNGAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHH 556
TC+ D+DEC +T C + C + + C C +GF +G C D N + C
Sbjct: 1242 TCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE 1300
Query: 557 GRCVDGIASFSCACA---------PGYTGTRCESQVDECRSQPCRHGGKC------LDLV 601
C + SF C CA G +R + +D QP +C L
Sbjct: 1301 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1360
Query: 602 DKYL--------CRCPSGT-TGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGP 652
D L C C SG G NCE+ PC G + +C G
Sbjct: 1361 DNVLAPNVTKQECCCTSGAGWGDNCEI-------FPCPV----LGTAEFTEMCPKG---- 1405
Query: 653 LCNVEINECASSPCGEGGSCVDGEN---GFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
P GE S GEN CL E C +G C
Sbjct: 1406 --------KGFVPAGESSSEAGGENYKDADECLL---------------FGQEICKNGFC 1442
Query: 710 YDAPGGFRCVCEPG-WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC--PPGVQG 766
+ G+ C C+ G + P Q D C+ G C + ++C C P +
Sbjct: 1443 LNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDA 1502
Query: 767 RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC 826
+ + P E + E +C W+ D C+ P +
Sbjct: 1503 SEKRCI-----RPAESNEQIEETDVYQDLC-----WEH---LSDEYVCSRPL------VG 1543
Query: 827 TNLAGSFSCTCHGGYTGPSCD----QDIND----CD-PNPCLNGGSCQDGVGSFSCSCLP 877
+ C +G G C +D +D C+ P +D + FS P
Sbjct: 1544 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTP 1603
Query: 878 GFAGPRCARD----------VDEC-LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ--- 923
A P +D +EC + N C G C +TC C + G+H +
Sbjct: 1604 E-ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKM 1659
Query: 924 ---DLPDCSP-----SSCFNGGTCVDGVNSFSCLCRPGY 954
D+ +C S C N C++ S+ CLC PGY
Sbjct: 1660 TCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLPGY 1697
Score = 183 bits (464), Expect = 2e-45
Identities = 187/653 (28%), Positives = 259/653 (39%), Gaps = 116/653 (17%)
Query: 581 SQVDECRSQPCRHG-GKCLDLVDKYLCRCPSGTTGVNCE---VNIDDCAS--NPCTFGVC 634
++++EC P G G C++L +Y C C G + V+ID+C + C+ G C
Sbjct: 873 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 932
Query: 635 RDGINRYDCVCQPGFT----GPLCNVEINECASSP-CGEGGSCVDGENGFRC-LCPPGSL 688
+ + C+C GF G C ++++EC CGEG CV+ FRC C G
Sbjct: 933 ENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYR 990
Query: 689 PPL---------CLPPSHPCAHEPCSHGICYDAPGGFRCV-CEPGWSGPRCSQSLARDAC 738
CL PS C C ++PG ++CV C G+ G Q L D C
Sbjct: 991 MTQRGRCEDIDECLNPS------TCPDEQCVNSPGSYQCVPCTEGFRGWN-GQCLDVDEC 1043
Query: 739 ESQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPCTPNPCEHGGRCESAPGQLP 794
A G CS+ + C+C G + C + C G+C++ G
Sbjct: 1044 LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR 1103
Query: 795 VCSCPQGWQGPRCQ---QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCD 847
C+C QG+Q + +D+DEC C HG C N GSF C C GY G C+
Sbjct: 1104 -CTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCE 1161
Query: 848 QDINDC--DPNPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVDECLSNP--CGP-GT 900
DIN+C D + C G C + GS+ C+C GF + +D++EC +P CGP G
Sbjct: 1162 -DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGE 1218
Query: 901 CTDHVASFTCTCPPGYG----GFHCEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 955
C + SF C C G+ G CE D+ +C ++ C + G C + SF CLC Y
Sbjct: 1219 CLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLC---YQ 1274
Query: 956 GAHCQHEADPCLS-RPC-LHGGVCSAA-----HPGFRCTCLES------FTGPQCQ---- 998
G + C+ C L GVC A F C C + TG QC+
Sbjct: 1275 GFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTG-QCRSRTS 1333
Query: 999 TLVDWCSRQPCQNGGRCVQ----------------TGAYCLCPPG--WSGRLCDIRSLPC 1040
T +D QP + C T C C G W G C+I P
Sbjct: 1334 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW-GDNCEIFPCPV 1392
Query: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL--AQPCQHGGT 1098
A ++C G V S G ++ D CL Q G
Sbjct: 1393 LGTA-----EFTEMCPKGKGFVPAGES------SSEAGGENYKDADECLLFGQEICKNGF 1441
Query: 1099 CRGYMGGYMCECLPGYNGDNCE---DDVDECASQPCQHGGSCIDLVARYLCSC 1148
C GY C C G D + D+DEC G C++ Y C C
Sbjct: 1442 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1494
Score = 169 bits (429), Expect = 2e-41
Identities = 204/808 (25%), Positives = 299/808 (37%), Gaps = 167/808 (20%)
Query: 549 CSPDPCHHGRCVDGIASFSCACAPGY---TGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
C P +HG + C PGY T C+ ++EC+ Q G+CL+ + Y
Sbjct: 597 CPKKPSYHGY------NQMMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 649
Query: 606 CRCPSGTTGVNCEVNIDDCASNPCTF----GVCRDGINRYDCVCQP---GFTGPLCNVEI 658
C C G + C +P G C ++ P T LC +
Sbjct: 650 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 706
Query: 659 NECASSPCGEGGSC-VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
+ C + C + G F+ +CP G + H G + P +
Sbjct: 707 GKAWGPHCEK---CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQ 763
Query: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQCELLS 773
V + P ++ +A G + T PP + ++ L
Sbjct: 764 PVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEV----ATAPPEKEIPSLDQEKTKLE 819
Query: 774 PCTP-----------NPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-------QDVDECA 815
P P +P G E +PV P+ Q +++EC
Sbjct: 820 PGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECT 879
Query: 816 -GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCL-NGGSCQDGVGS 870
P CG G C NL ++C C+ GY + DI++C L + G C++ GS
Sbjct: 880 VNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGS 938
Query: 871 FSCSCLPGFA----GPRCARDVDECLS-NPCGPGTCTDHVASFTCT-CPPGYGGFH---C 921
F C C GF G C DVDECL + CG G C + V +F C C GY C
Sbjct: 939 FLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRC 997
Query: 922 EQDLPDC-SPSSCFNGGTCVDGVNSFSCL-CRPGYTGAHCQH-EADPCLSRPCLHGGVCS 978
E D+ +C +PS+C + CV+ S+ C+ C G+ G + Q + D CL G CS
Sbjct: 998 E-DIDECLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS 1055
Query: 979 AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSL 1038
+ C+C + +T + C++ C Q G LC
Sbjct: 1056 NLEGSYMCSCHKGYTRTP--------DHKHCRDIDECQQ------------GNLC----- 1090
Query: 1039 PCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE---QEVDPCLAQPCQH 1095
GQC + + S C C +G S + +++D C +
Sbjct: 1091 ------------------VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA 1132
Query: 1096 GGTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCP 1149
G CR G + C C GY GD+CED ++EC CQ G CI+ Y C+CP
Sbjct: 1133 HGQCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQRG-DCINTAGSYDCTCP 1190
Query: 1150 PGTL---GVLCE-INEDD----CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT--- 1198
G C+ INE + CGP G C++ G F C C G++
Sbjct: 1191 DGFQLDDNKTCQDINECEHPGLCGP------------QGECLNTEGSFHCVCQQGFSISA 1238
Query: 1199 -GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
G CE DI+EC + +H + G FRCLC+ GF P+ + Q C
Sbjct: 1239 DGRTCE-DIDECVNNTVCDSH--GFCDNTAGSFRCLCYQGFQAPQ--------DGQGCVD 1287
Query: 1258 GGQCRPSPGPGGGL-------TFTCHCA 1278
+C G G +F C CA
Sbjct: 1288 VNECELLSGVCGEAFCENVEGSFLCVCA 1315
Score = 156 bits (395), Expect = 2e-37
Identities = 197/739 (26%), Positives = 290/739 (39%), Gaps = 134/739 (18%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVG--ERCQLEDPCHSGPCAGRGVCQSSVVAG 100
CL+ S C + +C P C G+ G +C D C G C +
Sbjct: 1003 CLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNL---- 1057
Query: 101 TARFSCRCPRGF-RGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
+ C C +G+ R PD C D C +C +G F C+C GYQ + +
Sbjct: 1058 EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGYQLSAAK 1116
Query: 157 S---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAP--SPCR 207
D+DEC+ C HG C NT GSF+C C GY G CE+ C S C+
Sbjct: 1117 DQCEDIDECQHRHLCAHG-QCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQ 1174
Query: 208 NGGTCRQSGDLTYDCACLPGFE---GQNCEVNVDDC--PGHRCLNGGTCVDGVNTYNCQC 262
G +G +YDC C GF+ + C+ ++++C PG C G C++ +++C C
Sbjct: 1175 RGDCINTAG--SYDCTCPDGFQLDDNKTCQ-DINECEHPG-LCGPQGECLNTEGSFHCVC 1230
Query: 263 PPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQN 314
++ G+ C ED+DEC + C + G C NT G C+C G+ G+ C +
Sbjct: 1231 QQGFSISADGRTC-EDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV-D 1287
Query: 315 IDDCA--TAVCFHGATCHDRVASFYCAC--------PM-GKTGLLCHLD-DACVSNPCHE 362
+++C + VC A C + SF C C PM G+ D D V P E
Sbjct: 1288 VNECELLSGVCGE-AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1346
Query: 363 DAICDTNPVNGRAIC--TCPPGFTGGACDQDVDECSIGAN--------PCEHLGRCVNTQ 412
C N +N ++C P T C C+ GA PC LG T+
Sbjct: 1347 KKECYYN-LNDASLCDNVLAPNVTKQECC-----CTSGAGWGDNCEIFPCPVLGTAEFTE 1400
Query: 413 GSFLCQCGRGYT---------GPRCETDVNECL---SGPCRNQATCLDRIGQFTCICMAG 460
+C G+G+ G D +ECL C+N CL+ + C C G
Sbjct: 1401 ---MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQG 1456
Query: 461 FTGTYCE------VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST 514
TY + D+DECQ G C + ++C C LD E
Sbjct: 1457 ---TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMV-----LDASEKRCI 1508
Query: 515 PCRNGAKCVDQPDGYECRCAEGFEGT-LCDRNV---DDCSPDPCHHGRCVDGIA-SFSCA 569
+ +++ D Y+ C E +C R + + C C+ G A CA
Sbjct: 1509 RPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC----CLYGEAWGMQCA 1564
Query: 570 CAP----GYTGTRCESQVDECRSQPCRHGGKCL-DLVDKYLCRCPS---GTTGVNC--EV 619
P C V R QP +G L D ++Y +N E+
Sbjct: 1565 LCPLKDSDDYAQLCNIPVTG-RRQP--YGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL 1621
Query: 620 NIDDCAS-NPCTFGVCRDGINRYDCVCQPGF---TGPLCNVEINECAS-----SPCGEGG 670
++C N C G C Y C C G+ T + V++NEC S C +
Sbjct: 1622 QAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLC-KNA 1680
Query: 671 SCVDGENGFRCLCPPGSLP 689
C++ + ++CLC PG +P
Sbjct: 1681 KCINTDGSYKCLCLPGYVP 1699
Score = 128 bits (322), Expect = 6e-29
Identities = 182/755 (24%), Positives = 244/755 (32%), Gaps = 164/755 (21%)
Query: 645 CQPGF---TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
C PG+ C +INEC G C++ +RC C G P P C
Sbjct: 612 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPD---PTFSSCVP 667
Query: 702 EPC----SHGICYDAPGGFR--------------CVCEPGWS-GPRCSQSLARDACESQP 742
+P G CY R C C G + GP C + C
Sbjct: 668 DPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEK------CPLPG 721
Query: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH----GGRCESAPGQLPVCSC 798
A GMG+ + GV R+ P H G PV
Sbjct: 722 TAAFKEICPGGMGYTVS---GVHRRR----------PIHHHVGKGPVFVKPKNTQPVAKS 768
Query: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN-P 857
P ++ V+ GP +A T PS DQ+ +P P
Sbjct: 769 THPPPLPAKEEPVEALTFSREHGP-----GVAEPEVATAPPEKEIPSLDQEKTKLEPGQP 823
Query: 858 CLNGGSCQ---------------------DGVGSFSCSCLPGFAGPRCARDVDECLSNP- 895
L+ G + S S P +++EC NP
Sbjct: 824 QLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPD 883
Query: 896 -CGPGTCTDHVASFTCTCPPGYGGFHCEQ---DLPDCSP-SSCFNGGTCVDGVNSFSCLC 950
CG G C + +TC C GY ++ D+ +C+ + G C + SF C+C
Sbjct: 884 ICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCIC 943
Query: 951 RPGYTGAHCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC 1009
G+ + E C+ CL VC H C+ + +C+ C
Sbjct: 944 PAGFMASE---EGTNCIDVDECLRPDVCGEGH------CVNTVGAFRCEY---------C 985
Query: 1010 QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1069
+G R Q G C + I L QCV+ S+
Sbjct: 986 DSGYRMTQRGR-------------------CED----IDECLNPSTCPDEQCVNSPGSYQ 1022
Query: 1070 CV-CPEGRTGSHCE-QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDDV 1123
CV C EG G + + +VD CL G C G YMC C GY + +C D+
Sbjct: 1023 CVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DI 1081
Query: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
DEC G C + + C+C G +D C C H G C
Sbjct: 1082 DECQQGNLCVNGQCKNTEGSFRCTCGQ---GYQLSAAKDQCEDIDECQHRHLCAH-GQCR 1137
Query: 1184 DLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF- 1238
+ G F+C C GY G CE DINEC DC+ + G + C C GF
Sbjct: 1138 NTEGSFQCVCDQGYRASGLGDHCE-DINECLEDK-SVCQRGDCI-NTAGSYDCTCPDGFQ 1194
Query: 1239 --SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL-----TFTCHCAQPFW----GPRCE 1287
CQ + C+H G C GP G +F C C Q F G CE
Sbjct: 1195 LDDNKTCQDI------NECEHPGLC----GPQGECLNTEGSFHCVCQQGFSISADGRTCE 1244
Query: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGP 1322
+ C C T RC C G P
Sbjct: 1245 DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 1279
Score = 103 bits (256), Expect = 3e-21
Identities = 177/747 (23%), Positives = 246/747 (32%), Gaps = 137/747 (18%)
Query: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA--CESQPCRAGGTCSSDGMGF 756
C +P HG C PG+ R + + +D C+ Q G C + +
Sbjct: 597 CPKKPSYHGY------NQMMECLPGYK--RVNNTFCQDINECQLQGVCPNGECLNTMGSY 648
Query: 757 HCTCPPGVQGRQCELLSPCTPNP---CEHGGRCESAPG---------------QLPVCSC 798
CTC G S C P+P E G C QL CS
Sbjct: 649 RCTCKIGFGPDPT--FSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 706
Query: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG------------YTGPSC 846
+ W GP C++ C P IC G H + P
Sbjct: 707 GKAW-GPHCEK----CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKN 761
Query: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR----------DVDECLSNP- 895
Q + P L +FS PG A P A D ++ P
Sbjct: 762 TQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPG 821
Query: 896 ---CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP 952
PG T H+ P + G E+ P T +S S + P
Sbjct: 822 QPQLSPGISTIHLH-------PQFPGIVIEKTSPPVPVEVAPEAST-----SSASQVIAP 869
Query: 953 GYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGFRCTCLESFTGPQCQTL---VDWCSR-Q 1007
E + C P + G G C + C C E + + Q +D C++ Q
Sbjct: 870 TQVT-----EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQ 924
Query: 1008 PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
+ GRC T G++ C+CP G+ + E +C G CV+
Sbjct: 925 HLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP------DVC-GEGHCVNTV 977
Query: 1066 SSHYC-VCPEG---RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGDNCE 1120
+ C C G CE ++D CL C G Y C C G+ G N +
Sbjct: 978 GAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ 1036
Query: 1121 D-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
DVDEC G C +L Y+CSC G + C G C+ N
Sbjct: 1037 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP---DHKHCRDIDECQQGNLCV-N 1092
Query: 1180 GTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
G C + G FRCTC GY +CE DI+EC+ H C ++ G F+C+C
Sbjct: 1093 GQCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHR--HLCAHGQC-RNTEGSFQCVCD 1148
Query: 1236 AGFS----GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW---GPRCER 1288
G+ G C+ + E + G C + G ++ C C F C+
Sbjct: 1149 QGYRASGLGDHCEDINECLEDKSVCQRGDCINTAG-----SYDCTCPDGFQLDDNKTCQD 1203
Query: 1289 VARSCRELQCPVGVPCQQTPRGPRCACPPGLS----GPSCRSFPGSPPGASNASCAAAPC 1344
+ C C T C C G S G +C +N C +
Sbjct: 1204 INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC---VNNTVCDSH-- 1258
Query: 1345 LHGGSCRPAPLAPFFRCACAQGWTGPR 1371
G C A FRC C QG+ P+
Sbjct: 1259 ---GFCDNT--AGSFRCLCYQGFQAPQ 1280
Score = 50.4 bits (119), Expect = 2e-05
Identities = 42/151 (27%), Positives = 59/151 (39%), Gaps = 17/151 (11%)
Query: 1091 QPCQHGGTCRGYMGGYMCECLPGY---NGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
Q C + GY M ECLPGY N C+ D++EC Q G C++ + Y C+
Sbjct: 595 QKCPKKPSYHGY--NQMMECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCT 651
Query: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLV-GGFRCTCPPGYTGLRCEADI 1206
C +G + C P PP+ S + G C LV G +C P + +
Sbjct: 652 C---KIGFGPDPTFSSCVPDPPVISEEK----GPCYRLVSSGRQCMHP---LSVHLTKQL 701
Query: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
C G H C F+ +C G
Sbjct: 702 CCCSVGKAWGPHCEKCPLPGTAAFKEICPGG 732
Score = 45.4 bits (106), Expect = 6e-04
Identities = 95/370 (25%), Positives = 136/370 (36%), Gaps = 83/370 (22%)
Query: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649
PC +GG+C DK C+CP TG C++ + AS P Y QPG
Sbjct: 406 PCMNGGQCSSR-DK--CQCPPNFTGKLCQIPVHG-ASVP----------KLYQHSQQPGK 451
Query: 650 TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
L I+ + P V + G + PP + + HP H +
Sbjct: 452 A--LGTHVIHSTHTLPL-----TVTSQQGVKVKFPPNIVN---IHVKHPPEASVQIHQVS 501
Query: 710 -YDAPGGFRCV-CEPGWSGP-------RCSQSLARDACESQ------PCRAG---GTCSS 751
D P G + +PG S + +Q++ Q P A G C
Sbjct: 502 RIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQ 561
Query: 752 DGMGFHC-TCPPGVQGRQ--CELLSPCTP-NPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807
+ +G C PG+ ++ C + N C+ + S G + C G++
Sbjct: 562 ETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN 621
Query: 808 Q--QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL---NGG 862
QD++EC C P+G C N GS+ CTC G+ GP D + C P+P + G
Sbjct: 622 TFCQDINECQLQGVC-PNGECLNTMGSYRCTCKIGF-GP--DPTFSSCVPDPPVISEEKG 677
Query: 863 SCQDGVGSFS--------------CSCLPGFA-GPRCARDVDECLSNPCGPGTCTDHVAS 907
C V S C C G A GP C ++C PGT A+
Sbjct: 678 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHC----EKCPL----PGT-----AA 724
Query: 908 FTCTCPPGYG 917
F CP G G
Sbjct: 725 FKEICPGGMG 734
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 143 LCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
+ C PGY+ + D++EC++ C +G CLNT GS+RC C G+ + VP
Sbjct: 609 MMECLPGYKRVNNTFCQDINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVP 667
Query: 201 CAPSPCRNGGTC 212
P G C
Sbjct: 668 DPPVISEEKGPC 679
Score = 43.9 bits (102), Expect = 0.002
Identities = 46/166 (27%), Positives = 59/166 (35%), Gaps = 33/166 (19%)
Query: 3 PGARGRRRRR---------RPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGG 53
PG R RR + + PPPPPPP A P A PG P G P
Sbjct: 77 PGVPSERTRRTSKPGGAALQGLRPPPPPPPEPARP-----AVPGGQLHPNPGGHPA---- 127
Query: 54 RCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFR 113
AA G R ++ SG + V Q + G RC G+
Sbjct: 128 ---------AAPFTKQGRQVVRSKVPQETQSGGGSRLQVHQKQQLQGVNVCGGRCCHGWS 178
Query: 114 GPDCS--LPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS 157
S P PC +G C + P LC C PG +G++C +
Sbjct: 179 KAPGSQRCTKPSCVPPCQNGGMC-LRPQ---LCVCKPGTKGKACET 220
Score = 42.0 bits (97), Expect = 0.007
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 21/91 (23%)
Query: 270 FCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW----TGESC-------SQNIDDC 318
FC +D++ECQLQ C NG C NT+G + C C G+ T SC S+ C
Sbjct: 623 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 679
Query: 319 ATAV-----CFHGATCHDRVASFYCACPMGK 344
V C H + H + C C +GK
Sbjct: 680 YRLVSSGRQCMHPLSVH--LTKQLCCCSVGK 708
Score = 40.4 bits (93), Expect = 0.020
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 720 CEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779
C GWS SQ + +C PC+ GG C + C C PG +G+ CE ++ +
Sbjct: 173 CCHGWSKAPGSQRCTKPSCVP-PCQNGGMCLRPQL---CVCKPGTKGKACETIAAQDTSS 228
Query: 780 CEHGGRCESA 789
GG+ A
Sbjct: 229 PVFGGQSPGA 238
Score = 38.5 bits (88), Expect = 0.078
Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 20/70 (28%)
Query: 165 GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCAC 224
G C HG + PGS RC P+ C P PC+NGG C + C C
Sbjct: 170 GGRCCHGWS--KAPGSQRCTKPS-------------CVP-PCQNGGMCLR----PQLCVC 209
Query: 225 LPGFEGQNCE 234
PG +G+ CE
Sbjct: 210 KPGTKGKACE 219
Score = 38.1 bits (87), Expect = 0.10
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
Query: 405 LGRCVN-TQGSFLCQCGRGYTGPRCETDV----------NECLSGPCRNQATCLDRIGQF 453
LGRC T GS QCG+ G + D N+C P + +++ +
Sbjct: 556 LGRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME- 611
Query: 454 TCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF 499
C+ G+ T+C+ DI+ECQ G C + + + CTC GF
Sbjct: 612 ---CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 656
Score = 37.0 bits (84), Expect = 0.23
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
PC+NGG C R C CP F+G CQ+ V
Sbjct: 406 PCMNGGQCSSRDK---CQCPPNFTGKLCQIPV 434
Score = 37.0 bits (84), Expect = 0.23
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
PC NGG+C C CPP ++G+LC I
Sbjct: 406 PCMNGGQCSSRDK-CQCPPNFTGKLCQI 432
Score = 36.2 bits (82), Expect = 0.38
Identities = 33/103 (32%), Positives = 35/103 (33%), Gaps = 30/103 (29%)
Query: 2113 GPPASPGGFPLEGPYAAATATAV-------SLAQLGGPGRAGLG--------RQPPGGCV 2157
GP + G PL GP + T S A G P RA G PGG
Sbjct: 35 GPGLAAGALPLSGPPRSRTFNVALNARYSRSSAAAGAPSRASPGVPSERTRRTSKPGGAA 94
Query: 2158 LSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQL-LNPG 2199
L L PP PP P P PG QL NPG
Sbjct: 95 LQ--------------GLRPPPPPPPEPARPAVPGGQLHPNPG 123
Score = 36.2 bits (82), Expect = 0.38
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 17/64 (26%)
Query: 971 CLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSG 1030
C HG S A RCT P C PCQNGG C++ C+C PG G
Sbjct: 173 CCHGW--SKAPGSQRCT------KPSCVP--------PCQNGGMCLRP-QLCVCKPGTKG 215
Query: 1031 RLCD 1034
+ C+
Sbjct: 216 KACE 219
Score = 36.2 bits (82), Expect = 0.38
Identities = 59/268 (22%), Positives = 89/268 (33%), Gaps = 54/268 (20%)
Query: 1087 PCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGS--------CI 1138
P PCQ+GG C + +C C PG G CE + S P G S
Sbjct: 189 PSCVPPCQNGGMC---LRPQLCVCKPGTKGKACETIAAQDTSSPVFGGQSPGAASSWGPP 245
Query: 1139 DLVARYLCSCPPGTLGVLCEINEDDCGPGP---------------PLDSGPRCLHNGTCV 1183
+ A++ S TL + + + P PL S +H+G
Sbjct: 246 EQAAKHTSSKKADTLPRVSPVAQMTLTLKPKPSVGLPQQIHSQVTPLSSQSVVIHHGQTQ 305
Query: 1184 DLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRC 1243
+ V P Y + + G+ + +D + P F+ H G R
Sbjct: 306 EYV------LKPKYFPAQKGISGEQSTEGSFPLRYVQDQVAAP---FQLSNHTG----RI 352
Query: 1244 QTVLSPCESQPCQHGGQCRPSPGPGGGLTFTC---HCAQPFWGPRCERVARSCRELQCPV 1300
+ V +P + G C+ S G T H A A + R + C
Sbjct: 353 KVVFTPSICKVTCTKGSCQNSCEKGNTTTLISENGHAADTL-------TATNFRVVIC-- 403
Query: 1301 GVPCQ---QTPRGPRCACPPGLSGPSCR 1325
+PC Q +C CPP +G C+
Sbjct: 404 HLPCMNGGQCSSRDKCQCPPNFTGKLCQ 431
Score = 36.2 bits (82), Expect = 0.38
Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
PC +GG C + +CQCP +TG LC+ P
Sbjct: 406 PCMNGGQCSSRD---KCQCPPNFTGKLCQIP 433
Score = 35.8 bits (81), Expect = 0.50
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 6/36 (16%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCH 83
PC NGG+C+ SR+ C CPP + G+ CQ+ P H
Sbjct: 406 PCMNGGQCS---SRDK-CQCPPNFTGKLCQI--PVH 435
Score = 35.4 bits (80), Expect = 0.66
Identities = 35/113 (30%), Positives = 42/113 (37%), Gaps = 20/113 (17%)
Query: 1058 GGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYN-- 1115
GGQ H P + G Q V + Q Q GG R + + + L G N
Sbjct: 115 GGQLHPNPGGHPAAAPFTKQG---RQVVRSKVPQETQSGGGSR--LQVHQKQQLQGVNVC 169
Query: 1116 -GDNCEDDVDECASQ---------PCQHGGSCIDLVARYLCSCPPGTLGVLCE 1158
G C SQ PCQ+GG C+ LC C PGT G CE
Sbjct: 170 GGRCCHGWSKAPGSQRCTKPSCVPPCQNGGMCL---RPQLCVCKPGTKGKACE 219
Score = 35.0 bits (79), Expect = 0.86
Identities = 58/224 (25%), Positives = 75/224 (33%), Gaps = 26/224 (11%)
Query: 725 SGPRCSQS--LARDACESQPCRAGGTCSSDGMGFHC-----TCPPGVQGRQCELLSPCTP 777
SGP S++ +A +A S+ A G S G T PG G + L P P
Sbjct: 46 SGPPRSRTFNVALNARYSRSSAAAGAPSRASPGVPSERTRRTSKPG--GAALQGLRPPPP 103
Query: 778 NPCEH------GGRCESAPGQLPVCS--CPQGWQGPRCQQDVDECAGPAPCGPHGICTNL 829
P E GG+ PG P + QG Q R + + +G L
Sbjct: 104 PPPEPARPAVPGGQLHPNPGGHPAAAPFTKQGRQVVRSKVPQETQSGGGSRLQVHQKQQL 163
Query: 830 AGSFSC---TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR 886
G C CHG P + PC NGG C + C C PG G C
Sbjct: 164 QGVNVCGGRCCHGWSKAPGSQRCTKPSCVPPCQNGGMC---LRPQLCVCKPGTKGKACET 220
Query: 887 DVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSP 930
+ S+P G +S+ PP H D P
Sbjct: 221 IAAQDTSSPVFGGQSPGAASSWG---PPEQAAKHTSSKKADTLP 261
Score = 34.7 bits (78), Expect = 1.1
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 189 YTGPLCENPAVPCAPSPCRNGGTCRQSGDLTY---DCACLPGFEGQNCEVNVDDCPGHRC 245
+T +C+ V C C+N +C + T + N V + P C
Sbjct: 356 FTPSICK---VTCTKGSCQN--SCEKGNTTTLISENGHAADTLTATNFRVVICHLP---C 407
Query: 246 LNGGTCVDGVNTYNCQCPPEWTGQFC 271
+NGG C + CQCPP +TG+ C
Sbjct: 408 MNGGQCS---SRDKCQCPPNFTGKLC 430
Score = 33.5 bits (75), Expect = 2.5
Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 11/63 (17%)
Query: 1229 GFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQC-RPSPGPGGGLTFTCHCAQPFWGPRCE 1287
G RC CH P Q P PCQ+GG C RP C C G CE
Sbjct: 170 GGRC-CHGWSKAPGSQRCTKPSCVPPCQNGGMCLRPQ---------LCVCKPGTKGKACE 219
Query: 1288 RVA 1290
+A
Sbjct: 220 TIA 222
Score = 33.5 bits (75), Expect = 2.5
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRH 170
PC +G +CS R C CPP + G+ C+ V V + +H
Sbjct: 406 PCMNGGQCS----SRDKCQCPPNFTGKLCQIPVHGASVPKLYQH 445
Score = 33.5 bits (75), Expect = 2.5
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
PC +GG C +R C CPP G LC+I
Sbjct: 406 PCMNGGQCS---SRDKCQCPPNFTGKLCQI 432
Score = 33.5 bits (75), Expect = 2.5
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 862 GSC-QDGVGSFSCSCLPGFAGPR-CARDV------DECLSNPCGPGTCTDHVASFTCTCP 913
G C Q+ +GS LPG + C V ++C P P H + C
Sbjct: 557 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSY---HGYNQMMECL 613
Query: 914 PGY---GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHC------- 959
PGY C QD+ +C G C++ + S+ C C+ G+ T + C
Sbjct: 614 PGYKRVNNTFC-QDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 672
Query: 960 QHEADPCL-----SRPCLH 973
E PC R C+H
Sbjct: 673 SEEKGPCYRLVSSGRQCMH 691
Score = 33.5 bits (75), Expect = 2.5
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 16/97 (16%)
Query: 224 CLPGFEGQN---CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP----PEWTGQFCTEDVD 276
CLPG++ N C+ ++++C G C++ + +Y C C P+ T C D
Sbjct: 612 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 670
Query: 277 ECQLQPNACH----NGGTCFNTLGGH----SCVCVNG 305
+ C+ +G C + L H C C G
Sbjct: 671 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 707
Score = 32.3 bits (72), Expect = 5.6
Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 13/72 (18%)
Query: 557 GRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVN 616
GRC G + APG RC C PC++GG CL LC C GT G
Sbjct: 171 GRCCHGWSK-----APG--SQRCTKP--SC-VPPCQNGGMCLR---PQLCVCKPGTKGKA 217
Query: 617 CEVNIDDCASNP 628
CE S+P
Sbjct: 218 CETIAAQDTSSP 229
Score = 32.3 bits (72), Expect = 5.6
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 926 PDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAA 980
P C P C NGG C+ C+C+PG G C+ A S P G AA
Sbjct: 189 PSCVPP-CQNGGMCL---RPQLCVCKPGTKGKACETIAAQDTSSPVFGGQSPGAA 239
Score = 31.6 bits (70), Expect = 9.5
Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 18/77 (23%)
Query: 173 TCLNTPGSFRCQCPAGYTGPLCE------------NPAVPCAPSPCRNGGTCRQSGDLTY 220
TC T GS + C G T L N V PC NGG C
Sbjct: 364 TC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDK--- 418
Query: 221 DCACLPGFEGQNCEVNV 237
C C P F G+ C++ V
Sbjct: 419 -CQCPPNFTGKLCQIPV 434
>gi|46249412 latent transforming growth factor beta binding protein 1
isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 227 bits (578), Expect = 1e-58
Identities = 237/870 (27%), Positives = 341/870 (39%), Gaps = 146/870 (16%)
Query: 469 DIDECQSSPCVNG-GVCKDRVNGFSCTCPSGFSGSTCQ---LDVDECASTP--CRNGAKC 522
+I+EC +P + G G C + ++C C G+ S Q +D+DEC C G +C
Sbjct: 548 EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQG-RC 606
Query: 523 VDQPDGYECRCAEGF----EGTLCDRNVDDC-SPDPCHHGRCVDGIASFSCA-CAPGYTG 576
+ + C C GF EGT C +VD+C PD C G CV+ + +F C C GY
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRM 665
Query: 577 T---RCESQVDECRSQPCRHGGKCLDLVDKYLC-RCPSGTTGVNCE-VNIDDCAS-NPCT 630
T RCE +DEC + +C++ Y C C G G N + +++D+C N C
Sbjct: 666 TQRGRCED-IDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCA 724
Query: 631 FGVCRDGINRYDCVCQPGFTGPLCNV---EINECASSPCGEGGSCVDGENGFRCLCPPG- 686
G C + Y C C G+T + +I+EC G C + E FRC C G
Sbjct: 725 NGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRCTCGQGY 784
Query: 687 --SLPPLCLPPSHPCAHEP-CSHGICYDAPGGFRCVCEPGWS----GPRCSQSLARDACE 739
S C H C+HG C + G F+CVC+ G+ G C + E
Sbjct: 785 QLSAAKDQCEDIDECQHRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED--INECLE 842
Query: 740 SQPCRAGGTCSSDGMGFHCTCPPGVQ---GRQCELLSPCT-PNPCEHGGRCESAPGQLPV 795
+ G C + + CTCP G Q + C+ ++ C P C G C + G
Sbjct: 843 DKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECEHPGLCGPQGECLNTEGSFH- 901
Query: 796 CSCPQGWQ----GPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ--- 848
C C QG+ G C+ D+DEC C HG C N AGSF C C+ G+ P Q
Sbjct: 902 CVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV 960
Query: 849 DINDCDPNPCLNGGS-CQDGVGSFSCSC---------LPGFAGPRCARDVD--------- 889
D+N+C+ + G + C++ GSF C C + G R + D+D
Sbjct: 961 DVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
Query: 890 --ECLSNPCGPGTCTD----HVASFTCTCPPGYG-GFHCEQDLPDCSPSSCFNGGTCVDG 942
EC N C + +V C C G G G +CE + C V G
Sbjct: 1021 KKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGWGDNCE--IFPCP----------VLG 1068
Query: 943 VNSFSCLCRPG-----------YTGAHCQHEADPCL--SRPCLHGGVCSAAHPGFRCTCL 989
F+ +C G G +AD CL + G C PG+ C C
Sbjct: 1069 TAEFTEMCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKNGFCLNTRPGYECYCK 1128
Query: 990 E-SFTGP---QCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREA 1043
+ ++ P QC + D C G+CV T G+Y C C + R + E+
Sbjct: 1129 QGTYYDPVKLQCFDM-DECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDASEKRCIRPAES 1187
Query: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM 1103
QI E+ C + S Y VC G CL G
Sbjct: 1188 NEQI----EETDVYQDLCWEHLSDEY-VCSRPLVGKQTTYTECCCL----------YGEA 1232
Query: 1104 GGYMCECLPGYNGDNCED--DVDECASQPCQHGGSCIDLVARYLCSCPP-----GTLGVL 1156
G C P + D+ ++ + + +D +Y P L
Sbjct: 1233 WGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTPEADPYFIQDRFLNSF 1292
Query: 1157 CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGY---TGLRCEADINEC---- 1209
E+ ++CG + +G NG CV + G+ C C GY T D+NEC
Sbjct: 1293 EELQAEECG----ILNG---CENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELN 1345
Query: 1210 -RSGACHAAHTRDCLQDPGGGFRCLCHAGF 1238
R C A C+ + G ++CLC G+
Sbjct: 1346 NRMSLCKNA---KCI-NTDGSYKCLCLPGY 1371
Score = 207 bits (527), Expect = 1e-52
Identities = 278/1059 (26%), Positives = 387/1059 (36%), Gaps = 249/1059 (23%)
Query: 16 SPPPPPPPVRALPLLLLLA----GPGAAAP-----------PCLDGSPCA-NGGRCTQLP 59
S PPP P + P+ L GPG A P P LD G+ P
Sbjct: 442 STHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLSP 501
Query: 60 SREAACLCP--PGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDC 117
L P PG V E+ P P A S V+A T +C
Sbjct: 502 GISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSA-SQVIAPTQVTEIN--------EC 552
Query: 118 SL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHGG 172
++ PD C + C + R+ C C GY Q R C D+DEC + G
Sbjct: 553 TVNPDICGAGHC-------INLPVRYTCICYEGYRFSEQQRKC-VDIDECTQVQHLCSQG 604
Query: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
C NT GSF C CPAG+ + EG N
Sbjct: 605 RCENTEGSFLCICPAGF-----------------------------------MASEEGTN 629
Query: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNCQ-CPPEW--TGQFCTEDVDECQLQPNACHNGG 289
C ++VD+C G CV+ V + C+ C + T + ED+DEC L P+ C +
Sbjct: 630 C-IDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDEC-LNPSTCPD-E 686
Query: 290 TCFNTLGGHSCV-CV---NGWTGESCSQNIDDCATA-VCFHGATCHDRVASFYCACPMGK 344
C N+ G + CV C GW G+ ++D+C VC +G C + S+ C+C G
Sbjct: 687 QCVNSPGSYQCVPCTEGFRGWNGQCL--DVDECLEPNVCANG-DCSNLEGSYMCSCHKGY 743
Query: 345 TGLLCH-----LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACD---QDVDECS 396
T H +D+ N C +T G CTC G+ A +D+DEC
Sbjct: 744 TRTPDHKHCRDIDECQQGNLCVNGQCKNT---EGSFRCTCGQGYQLSAAKDQCEDIDECQ 800
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGY----TGPRCETDVNECL--SGPCRNQATCLDRI 450
+ C H G+C NT+GSF C C +GY G CE D+NECL C+ + C++
Sbjct: 801 -HRHLCAH-GQCRNTEGSFQCVCDQGYRASGLGDHCE-DINECLEDKSVCQ-RGDCINTA 856
Query: 451 GQFTCICMAGF---TGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFS----GS 502
G + C C GF C+ DI+EC+ C G C + F C C GFS G
Sbjct: 857 GSYDCTCPDGFQLDDNKTCQ-DINECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGR 915
Query: 503 TCQLDVDECA-STPCRNGAKCVDQPDGYECRCAEGF----EGTLC-DRNVDDCSPDPCHH 556
TC+ D+DEC +T C + C + + C C +GF +G C D N + C
Sbjct: 916 TCE-DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVDVNECELLSGVCGE 974
Query: 557 GRCVDGIASFSCACA---------PGYTGTRCESQVDECRSQPCRHGGKC------LDLV 601
C + SF C CA G +R + +D QP +C L
Sbjct: 975 AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEEKKECYYNLNDASLC 1034
Query: 602 DKYL--------CRCPSGT-TGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGP 652
D L C C SG G NCE+ PC G + +C G
Sbjct: 1035 DNVLAPNVTKQECCCTSGAGWGDNCEI-------FPCPV----LGTAEFTEMCPKG---- 1079
Query: 653 LCNVEINECASSPCGEGGSCVDGEN---GFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
P GE S GEN CL E C +G C
Sbjct: 1080 --------KGFVPAGESSSEAGGENYKDADECLL---------------FGQEICKNGFC 1116
Query: 710 YDAPGGFRCVCEPG-WSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC--PPGVQG 766
+ G+ C C+ G + P Q D C+ G C + ++C C P +
Sbjct: 1117 LNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMVLDA 1176
Query: 767 RQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGIC 826
+ + P E + E +C W+ D C+ P +
Sbjct: 1177 SEKRCI-----RPAESNEQIEETDVYQDLC-----WEH---LSDEYVCSRPL------VG 1217
Query: 827 TNLAGSFSCTCHGGYTGPSCD----QDIND----CD-PNPCLNGGSCQDGVGSFSCSCLP 877
+ C +G G C +D +D C+ P +D + FS P
Sbjct: 1218 KQTTYTECCCLYGEAWGMQCALCPLKDSDDYAQLCNIPVTGRRQPYGRDALVDFSEQYTP 1277
Query: 878 GFAGPRCARD----------VDEC-LSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ--- 923
A P +D +EC + N C G C +TC C + G+H +
Sbjct: 1278 E-ADPYFIQDRFLNSFEELQAEECGILNGCENGRCVRVQEGYTCDC---FDGYHLDTAKM 1333
Query: 924 ---DLPDCSP-----SSCFNGGTCVDGVNSFSCLCRPGY 954
D+ +C S C N C++ S+ CLC PGY
Sbjct: 1334 TCVDVNECDELNNRMSLCKN-AKCINTDGSYKCLCLPGY 1371
Score = 183 bits (464), Expect = 2e-45
Identities = 187/653 (28%), Positives = 259/653 (39%), Gaps = 116/653 (17%)
Query: 581 SQVDECRSQPCRHG-GKCLDLVDKYLCRCPSGTTGVNCE---VNIDDCAS--NPCTFGVC 634
++++EC P G G C++L +Y C C G + V+ID+C + C+ G C
Sbjct: 547 TEINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRC 606
Query: 635 RDGINRYDCVCQPGFT----GPLCNVEINECASSP-CGEGGSCVDGENGFRC-LCPPGSL 688
+ + C+C GF G C ++++EC CGEG CV+ FRC C G
Sbjct: 607 ENTEGSFLCICPAGFMASEEGTNC-IDVDECLRPDVCGEG-HCVNTVGAFRCEYCDSGYR 664
Query: 689 PPL---------CLPPSHPCAHEPCSHGICYDAPGGFRCV-CEPGWSGPRCSQSLARDAC 738
CL PS C C ++PG ++CV C G+ G Q L D C
Sbjct: 665 MTQRGRCEDIDECLNPS------TCPDEQCVNSPGSYQCVPCTEGFRGWN-GQCLDVDEC 717
Query: 739 ESQPCRAGGTCSSDGMGFHCTCPPGV----QGRQCELLSPCTPNPCEHGGRCESAPGQLP 794
A G CS+ + C+C G + C + C G+C++ G
Sbjct: 718 LEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFR 777
Query: 795 VCSCPQGWQGPRCQ---QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYT----GPSCD 847
C+C QG+Q + +D+DEC C HG C N GSF C C GY G C+
Sbjct: 778 -CTCGQGYQLSAAKDQCEDIDECQHRHLCA-HGQCRNTEGSFQCVCDQGYRASGLGDHCE 835
Query: 848 QDINDC--DPNPCLNGGSCQDGVGSFSCSCLPGFA--GPRCARDVDECLSNP--CGP-GT 900
DIN+C D + C G C + GS+ C+C GF + +D++EC +P CGP G
Sbjct: 836 -DINECLEDKSVCQRG-DCINTAGSYDCTCPDGFQLDDNKTCQDINEC-EHPGLCGPQGE 892
Query: 901 CTDHVASFTCTCPPGYG----GFHCEQDLPDCSPSS-CFNGGTCVDGVNSFSCLCRPGYT 955
C + SF C C G+ G CE D+ +C ++ C + G C + SF CLC Y
Sbjct: 893 CLNTEGSFHCVCQQGFSISADGRTCE-DIDECVNNTVCDSHGFCDNTAGSFRCLC---YQ 948
Query: 956 GAHCQHEADPCLS-RPC-LHGGVCSAA-----HPGFRCTCLES------FTGPQCQ---- 998
G + C+ C L GVC A F C C + TG QC+
Sbjct: 949 GFQAPQDGQGCVDVNECELLSGVCGEAFCENVEGSFLCVCADENQEYSPMTG-QCRSRTS 1007
Query: 999 TLVDWCSRQPCQNGGRCVQ----------------TGAYCLCPPG--WSGRLCDIRSLPC 1040
T +D QP + C T C C G W G C+I P
Sbjct: 1008 TDLDVDVDQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW-GDNCEIFPCPV 1066
Query: 1041 REAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL--AQPCQHGGT 1098
A ++C G V S G ++ D CL Q G
Sbjct: 1067 LGTA-----EFTEMCPKGKGFVPAGES------SSEAGGENYKDADECLLFGQEICKNGF 1115
Query: 1099 CRGYMGGYMCECLPGYNGDNCE---DDVDECASQPCQHGGSCIDLVARYLCSC 1148
C GY C C G D + D+DEC G C++ Y C C
Sbjct: 1116 CLNTRPGYECYCKQGTYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFC 1168
Score = 169 bits (429), Expect = 2e-41
Identities = 204/808 (25%), Positives = 299/808 (37%), Gaps = 167/808 (20%)
Query: 549 CSPDPCHHGRCVDGIASFSCACAPGY---TGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
C P +HG + C PGY T C+ ++EC+ Q G+CL+ + Y
Sbjct: 271 CPKKPSYHGY------NQMMECLPGYKRVNNTFCQD-INECQLQGVCPNGECLNTMGSYR 323
Query: 606 CRCPSGTTGVNCEVNIDDCASNPCTF----GVCRDGINRYDCVCQP---GFTGPLCNVEI 658
C C G + C +P G C ++ P T LC +
Sbjct: 324 CTCK---IGFGPDPTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 380
Query: 659 NECASSPCGEGGSC-VDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFR 717
+ C + C + G F+ +CP G + H G + P +
Sbjct: 381 GKAWGPHCEK---CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQ 437
Query: 718 CVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQ----GRQCELLS 773
V + P ++ +A G + T PP + ++ L
Sbjct: 438 PVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEV----ATAPPEKEIPSLDQEKTKLE 493
Query: 774 PCTP-----------NPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-------QDVDECA 815
P P +P G E +PV P+ Q +++EC
Sbjct: 494 PGQPQLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECT 553
Query: 816 -GPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQ---DINDCDPNPCL-NGGSCQDGVGS 870
P CG G C NL ++C C+ GY + DI++C L + G C++ GS
Sbjct: 554 VNPDICGA-GHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGS 612
Query: 871 FSCSCLPGFA----GPRCARDVDECLS-NPCGPGTCTDHVASFTCT-CPPGYGGFH---C 921
F C C GF G C DVDECL + CG G C + V +F C C GY C
Sbjct: 613 FLCICPAGFMASEEGTNCI-DVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRC 671
Query: 922 EQDLPDC-SPSSCFNGGTCVDGVNSFSCL-CRPGYTGAHCQH-EADPCLSRPCLHGGVCS 978
E D+ +C +PS+C + CV+ S+ C+ C G+ G + Q + D CL G CS
Sbjct: 672 E-DIDECLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCS 729
Query: 979 AAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSL 1038
+ C+C + +T + C++ C Q G LC
Sbjct: 730 NLEGSYMCSCHKGYTRTP--------DHKHCRDIDECQQ------------GNLC----- 764
Query: 1039 PCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCE---QEVDPCLAQPCQH 1095
GQC + + S C C +G S + +++D C +
Sbjct: 765 ------------------VNGQCKNTEGSFRCTCGQGYQLSAAKDQCEDIDECQHRHLCA 806
Query: 1096 GGTCRGYMGGYMCECLPGYN----GDNCEDDVDECASQP--CQHGGSCIDLVARYLCSCP 1149
G CR G + C C GY GD+CED ++EC CQ G CI+ Y C+CP
Sbjct: 807 HGQCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQRG-DCINTAGSYDCTCP 864
Query: 1150 PGTL---GVLCE-INEDD----CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT--- 1198
G C+ INE + CGP G C++ G F C C G++
Sbjct: 865 DGFQLDDNKTCQDINECEHPGLCGP------------QGECLNTEGSFHCVCQQGFSISA 912
Query: 1199 -GLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQH 1257
G CE DI+EC + +H + G FRCLC+ GF P+ + Q C
Sbjct: 913 DGRTCE-DIDECVNNTVCDSH--GFCDNTAGSFRCLCYQGFQAPQ--------DGQGCVD 961
Query: 1258 GGQCRPSPGPGGGL-------TFTCHCA 1278
+C G G +F C CA
Sbjct: 962 VNECELLSGVCGEAFCENVEGSFLCVCA 989
Score = 156 bits (395), Expect = 2e-37
Identities = 197/739 (26%), Positives = 290/739 (39%), Gaps = 134/739 (18%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWVG--ERCQLEDPCHSGPCAGRGVCQSSVVAG 100
CL+ S C + +C P C G+ G +C D C G C +
Sbjct: 677 CLNPSTCPDE-QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNL---- 731
Query: 101 TARFSCRCPRGF-RGPD---CSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR 156
+ C C +G+ R PD C D C +C +G F C+C GYQ + +
Sbjct: 732 EGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVNGQCK-NTEGSFRCTCGQGYQLSAAK 790
Query: 157 S---DVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT----GPLCENPAVPCAP--SPCR 207
D+DEC+ C HG C NT GSF+C C GY G CE+ C S C+
Sbjct: 791 DQCEDIDECQHRHLCAHG-QCRNTEGSFQCVCDQGYRASGLGDHCED-INECLEDKSVCQ 848
Query: 208 NGGTCRQSGDLTYDCACLPGFE---GQNCEVNVDDC--PGHRCLNGGTCVDGVNTYNCQC 262
G +G +YDC C GF+ + C+ ++++C PG C G C++ +++C C
Sbjct: 849 RGDCINTAG--SYDCTCPDGFQLDDNKTCQ-DINECEHPG-LCGPQGECLNTEGSFHCVC 904
Query: 263 PPEWT----GQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWT----GESCSQN 314
++ G+ C ED+DEC + C + G C NT G C+C G+ G+ C +
Sbjct: 905 QQGFSISADGRTC-EDIDEC-VNNTVCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCV-D 961
Query: 315 IDDCA--TAVCFHGATCHDRVASFYCAC--------PM-GKTGLLCHLD-DACVSNPCHE 362
+++C + VC A C + SF C C PM G+ D D V P E
Sbjct: 962 VNECELLSGVCGE-AFCENVEGSFLCVCADENQEYSPMTGQCRSRTSTDLDVDVDQPKEE 1020
Query: 363 DAICDTNPVNGRAIC--TCPPGFTGGACDQDVDECSIGAN--------PCEHLGRCVNTQ 412
C N +N ++C P T C C+ GA PC LG T+
Sbjct: 1021 KKECYYN-LNDASLCDNVLAPNVTKQECC-----CTSGAGWGDNCEIFPCPVLGTAEFTE 1074
Query: 413 GSFLCQCGRGYT---------GPRCETDVNECL---SGPCRNQATCLDRIGQFTCICMAG 460
+C G+G+ G D +ECL C+N CL+ + C C G
Sbjct: 1075 ---MCPKGKGFVPAGESSSEAGGENYKDADECLLFGQEICKN-GFCLNTRPGYECYCKQG 1130
Query: 461 FTGTYCE------VDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAST 514
TY + D+DECQ G C + ++C C LD E
Sbjct: 1131 ---TYYDPVKLQCFDMDECQDPSSCIDGQCVNTEGSYNCFCTHPMV-----LDASEKRCI 1182
Query: 515 PCRNGAKCVDQPDGYECRCAEGFEGT-LCDRNV---DDCSPDPCHHGRCVDGIA-SFSCA 569
+ +++ D Y+ C E +C R + + C C+ G A CA
Sbjct: 1183 RPAESNEQIEETDVYQDLCWEHLSDEYVCSRPLVGKQTTYTECC----CLYGEAWGMQCA 1238
Query: 570 CAP----GYTGTRCESQVDECRSQPCRHGGKCL-DLVDKYLCRCPS---GTTGVNC--EV 619
P C V R QP +G L D ++Y +N E+
Sbjct: 1239 LCPLKDSDDYAQLCNIPVTG-RRQP--YGRDALVDFSEQYTPEADPYFIQDRFLNSFEEL 1295
Query: 620 NIDDCAS-NPCTFGVCRDGINRYDCVCQPGF---TGPLCNVEINECAS-----SPCGEGG 670
++C N C G C Y C C G+ T + V++NEC S C +
Sbjct: 1296 QAEECGILNGCENGRCVRVQEGYTCDCFDGYHLDTAKMTCVDVNECDELNNRMSLC-KNA 1354
Query: 671 SCVDGENGFRCLCPPGSLP 689
C++ + ++CLC PG +P
Sbjct: 1355 KCINTDGSYKCLCLPGYVP 1373
Score = 128 bits (322), Expect = 6e-29
Identities = 182/755 (24%), Positives = 244/755 (32%), Gaps = 164/755 (21%)
Query: 645 CQPGF---TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAH 701
C PG+ C +INEC G C++ +RC C G P P C
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPD---PTFSSCVP 341
Query: 702 EPC----SHGICYDAPGGFR--------------CVCEPGWS-GPRCSQSLARDACESQP 742
+P G CY R C C G + GP C + C
Sbjct: 342 DPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHCEK------CPLPG 395
Query: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH----GGRCESAPGQLPVCSC 798
A GMG+ + GV R+ P H G PV
Sbjct: 396 TAAFKEICPGGMGYTVS---GVHRRR----------PIHHHVGKGPVFVKPKNTQPVAKS 442
Query: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPN-P 857
P ++ V+ GP +A T PS DQ+ +P P
Sbjct: 443 THPPPLPAKEEPVEALTFSREHGP-----GVAEPEVATAPPEKEIPSLDQEKTKLEPGQP 497
Query: 858 CLNGGSCQ---------------------DGVGSFSCSCLPGFAGPRCARDVDECLSNP- 895
L+ G + S S P +++EC NP
Sbjct: 498 QLSPGISTIHLHPQFPGIVIEKTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPD 557
Query: 896 -CGPGTCTDHVASFTCTCPPGYGGFHCEQ---DLPDCSP-SSCFNGGTCVDGVNSFSCLC 950
CG G C + +TC C GY ++ D+ +C+ + G C + SF C+C
Sbjct: 558 ICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQHLCSQGRCENTEGSFLCIC 617
Query: 951 RPGYTGAHCQHEADPCLS-RPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC 1009
G+ + E C+ CL VC H C+ + +C+ C
Sbjct: 618 PAGFMASE---EGTNCIDVDECLRPDVCGEGH------CVNTVGAFRCEY---------C 659
Query: 1010 QNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHY 1069
+G R Q G C + I L QCV+ S+
Sbjct: 660 DSGYRMTQRGR-------------------CED----IDECLNPSTCPDEQCVNSPGSYQ 696
Query: 1070 CV-CPEGRTGSHCE-QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY----NGDNCEDDV 1123
CV C EG G + + +VD CL G C G YMC C GY + +C D+
Sbjct: 697 CVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR-DI 755
Query: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
DEC G C + + C+C G +D C C H G C
Sbjct: 756 DECQQGNLCVNGQCKNTEGSFRCTCGQ---GYQLSAAKDQCEDIDECQHRHLCAH-GQCR 811
Query: 1184 DLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGF- 1238
+ G F+C C GY G CE DINEC DC+ + G + C C GF
Sbjct: 812 NTEGSFQCVCDQGYRASGLGDHCE-DINECLEDK-SVCQRGDCI-NTAGSYDCTCPDGFQ 868
Query: 1239 --SGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGL-----TFTCHCAQPFW----GPRCE 1287
CQ + C+H G C GP G +F C C Q F G CE
Sbjct: 869 LDDNKTCQDI------NECEHPGLC----GPQGECLNTEGSFHCVCQQGFSISADGRTCE 918
Query: 1288 RVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGP 1322
+ C C T RC C G P
Sbjct: 919 DIDECVNNTVCDSHGFCDNTAGSFRCLCYQGFQAP 953
Score = 103 bits (256), Expect = 3e-21
Identities = 177/747 (23%), Positives = 246/747 (32%), Gaps = 137/747 (18%)
Query: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA--CESQPCRAGGTCSSDGMGF 756
C +P HG C PG+ R + + +D C+ Q G C + +
Sbjct: 271 CPKKPSYHGY------NQMMECLPGYK--RVNNTFCQDINECQLQGVCPNGECLNTMGSY 322
Query: 757 HCTCPPGVQGRQCELLSPCTPNP---CEHGGRCESAPG---------------QLPVCSC 798
CTC G S C P+P E G C QL CS
Sbjct: 323 RCTCKIGFGPDPT--FSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSV 380
Query: 799 PQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGG------------YTGPSC 846
+ W GP C++ C P IC G H + P
Sbjct: 381 GKAW-GPHCEK----CPLPGTAAFKEICPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKN 435
Query: 847 DQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCAR----------DVDECLSNP- 895
Q + P L +FS PG A P A D ++ P
Sbjct: 436 TQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPG 495
Query: 896 ---CGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRP 952
PG T H+ P + G E+ P T +S S + P
Sbjct: 496 QPQLSPGISTIHLH-------PQFPGIVIEKTSPPVPVEVAPEAST-----SSASQVIAP 543
Query: 953 GYTGAHCQHEADPCLSRPCLHG-GVCSAAHPGFRCTCLESFTGPQCQTL---VDWCSR-Q 1007
E + C P + G G C + C C E + + Q +D C++ Q
Sbjct: 544 TQVT-----EINECTVNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQ 598
Query: 1008 PCQNGGRCVQT-GAY-CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
+ GRC T G++ C+CP G+ + E +C G CV+
Sbjct: 599 HLCSQGRCENTEGSFLCICPAGFMASEEGTNCIDVDECLRP------DVC-GEGHCVNTV 651
Query: 1066 SSHYC-VCPEG---RTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMC-ECLPGYNGDNCE 1120
+ C C G CE ++D CL C G Y C C G+ G N +
Sbjct: 652 GAFRCEYCDSGYRMTQRGRCE-DIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRGWNGQ 710
Query: 1121 D-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
DVDEC G C +L Y+CSC G + C G C+ N
Sbjct: 711 CLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTP---DHKHCRDIDECQQGNLCV-N 766
Query: 1180 GTCVDLVGGFRCTCPPGY----TGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCH 1235
G C + G FRCTC GY +CE DI+EC+ H C ++ G F+C+C
Sbjct: 767 GQCKNTEGSFRCTCGQGYQLSAAKDQCE-DIDECQHR--HLCAHGQC-RNTEGSFQCVCD 822
Query: 1236 AGFS----GPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFW---GPRCER 1288
G+ G C+ + E + G C + G ++ C C F C+
Sbjct: 823 QGYRASGLGDHCEDINECLEDKSVCQRGDCINTAG-----SYDCTCPDGFQLDDNKTCQD 877
Query: 1289 VARSCRELQCPVGVPCQQTPRGPRCACPPGLS----GPSCRSFPGSPPGASNASCAAAPC 1344
+ C C T C C G S G +C +N C +
Sbjct: 878 INECEHPGLCGPQGECLNTEGSFHCVCQQGFSISADGRTCEDIDEC---VNNTVCDSH-- 932
Query: 1345 LHGGSCRPAPLAPFFRCACAQGWTGPR 1371
G C A FRC C QG+ P+
Sbjct: 933 ---GFCDNT--AGSFRCLCYQGFQAPQ 954
Score = 50.4 bits (119), Expect = 2e-05
Identities = 42/151 (27%), Positives = 59/151 (39%), Gaps = 17/151 (11%)
Query: 1091 QPCQHGGTCRGYMGGYMCECLPGY---NGDNCEDDVDECASQPCQHGGSCIDLVARYLCS 1147
Q C + GY M ECLPGY N C+ D++EC Q G C++ + Y C+
Sbjct: 269 QKCPKKPSYHGY--NQMMECLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCT 325
Query: 1148 CPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLV-GGFRCTCPPGYTGLRCEADI 1206
C +G + C P PP+ S + G C LV G +C P + +
Sbjct: 326 C---KIGFGPDPTFSSCVPDPPVISEEK----GPCYRLVSSGRQCMHP---LSVHLTKQL 375
Query: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
C G H C F+ +C G
Sbjct: 376 CCCSVGKAWGPHCEKCPLPGTAAFKEICPGG 406
Score = 45.4 bits (106), Expect = 6e-04
Identities = 95/370 (25%), Positives = 136/370 (36%), Gaps = 83/370 (22%)
Query: 590 PCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGF 649
PC +GG+C DK C+CP TG C++ + AS P Y QPG
Sbjct: 80 PCMNGGQCSSR-DK--CQCPPNFTGKLCQIPVHG-ASVP----------KLYQHSQQPGK 125
Query: 650 TGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGIC 709
L I+ + P V + G + PP + + HP H +
Sbjct: 126 A--LGTHVIHSTHTLPL-----TVTSQQGVKVKFPPNIVN---IHVKHPPEASVQIHQVS 175
Query: 710 -YDAPGGFRCV-CEPGWSGP-------RCSQSLARDACESQ------PCRAG---GTCSS 751
D P G + +PG S + +Q++ Q P A G C
Sbjct: 176 RIDGPTGQKTKEAQPGQSQVSYQGLPVQKTQTIHSTYSHQQVIPHVYPVAAKTQLGRCFQ 235
Query: 752 DGMGFHC-TCPPGVQGRQ--CELLSPCTP-NPCEHGGRCESAPGQLPVCSCPQGWQGPRC 807
+ +G C PG+ ++ C + N C+ + S G + C G++
Sbjct: 236 ETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMMECLPGYKRVNN 295
Query: 808 Q--QDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCL---NGG 862
QD++EC C P+G C N GS+ CTC G+ GP D + C P+P + G
Sbjct: 296 TFCQDINECQLQGVC-PNGECLNTMGSYRCTCKIGF-GP--DPTFSSCVPDPPVISEEKG 351
Query: 863 SCQDGVGSFS--------------CSCLPGFA-GPRCARDVDECLSNPCGPGTCTDHVAS 907
C V S C C G A GP C ++C PGT A+
Sbjct: 352 PCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKAWGPHC----EKCPL----PGT-----AA 398
Query: 908 FTCTCPPGYG 917
F CP G G
Sbjct: 399 FKEICPGGMG 408
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 143 LCSCPPGYQ--GRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
+ C PGY+ + D++EC++ C +G CLNT GS+RC C G+ + VP
Sbjct: 283 MMECLPGYKRVNNTFCQDINECQLQGVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVP 341
Query: 201 CAPSPCRNGGTC 212
P G C
Sbjct: 342 DPPVISEEKGPC 353
Score = 42.0 bits (97), Expect = 0.007
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 21/91 (23%)
Query: 270 FCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGW----TGESC-------SQNIDDC 318
FC +D++ECQLQ C NG C NT+G + C C G+ T SC S+ C
Sbjct: 297 FC-QDINECQLQ-GVCPNG-ECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVISEEKGPC 353
Query: 319 ATAV-----CFHGATCHDRVASFYCACPMGK 344
V C H + H + C C +GK
Sbjct: 354 YRLVSSGRQCMHPLSVH--LTKQLCCCSVGK 382
Score = 38.1 bits (87), Expect = 0.10
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 22/109 (20%)
Query: 405 LGRCVN-TQGSFLCQCGRGYTGPRCETDV----------NECLSGPCRNQATCLDRIGQF 453
LGRC T GS QCG+ G + D N+C P + +++ +
Sbjct: 230 LGRCFQETIGS---QCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYNQMME- 285
Query: 454 TCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGF 499
C+ G+ T+C+ DI+ECQ G C + + + CTC GF
Sbjct: 286 ---CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGF 330
Score = 37.0 bits (84), Expect = 0.23
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 477 PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV 508
PC+NGG C R C CP F+G CQ+ V
Sbjct: 80 PCMNGGQCSSRDK---CQCPPNFTGKLCQIPV 108
Score = 37.0 bits (84), Expect = 0.23
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCDI 1035
PC NGG+C C CPP ++G+LC I
Sbjct: 80 PCMNGGQCSSRDK-CQCPPNFTGKLCQI 106
Score = 36.2 bits (82), Expect = 0.38
Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 167 PCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
PC +GG C + +CQCP +TG LC+ P
Sbjct: 80 PCMNGGQCSSRD---KCQCPPNFTGKLCQIP 107
Score = 35.8 bits (81), Expect = 0.50
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 6/36 (16%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCH 83
PC NGG+C+ SR+ C CPP + G+ CQ+ P H
Sbjct: 80 PCMNGGQCS---SRDK-CQCPPNFTGKLCQI--PVH 109
Score = 34.7 bits (78), Expect = 1.1
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 189 YTGPLCENPAVPCAPSPCRNGGTCRQSGDLTY---DCACLPGFEGQNCEVNVDDCPGHRC 245
+T +C+ V C C+N +C + T + N V + P C
Sbjct: 30 FTPSICK---VTCTKGSCQN--SCEKGNTTTLISENGHAADTLTATNFRVVICHLP---C 81
Query: 246 LNGGTCVDGVNTYNCQCPPEWTGQFC 271
+NGG C + CQCPP +TG+ C
Sbjct: 82 MNGGQCS---SRDKCQCPPNFTGKLC 104
Score = 33.5 bits (75), Expect = 2.5
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query: 127 PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRH 170
PC +G +CS R C CPP + G+ C+ V V + +H
Sbjct: 80 PCMNGGQCS----SRDKCQCPPNFTGKLCQIPVHGASVPKLYQH 119
Score = 33.5 bits (75), Expect = 2.5
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
PC +GG C +R C CPP G LC+I
Sbjct: 80 PCMNGGQCS---SRDKCQCPPNFTGKLCQI 106
Score = 33.5 bits (75), Expect = 2.5
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 862 GSC-QDGVGSFSCSCLPGFAGPR-CARDV------DECLSNPCGPGTCTDHVASFTCTCP 913
G C Q+ +GS LPG + C V ++C P P H + C
Sbjct: 231 GRCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSY---HGYNQMMECL 287
Query: 914 PGY---GGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHC------- 959
PGY C QD+ +C G C++ + S+ C C+ G+ T + C
Sbjct: 288 PGYKRVNNTFC-QDINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPPVI 346
Query: 960 QHEADPCL-----SRPCLH 973
E PC R C+H
Sbjct: 347 SEEKGPCYRLVSSGRQCMH 365
Score = 33.5 bits (75), Expect = 2.5
Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 16/97 (16%)
Query: 224 CLPGFEGQN---CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCP----PEWTGQFCTEDVD 276
CLPG++ N C+ ++++C G C++ + +Y C C P+ T C D
Sbjct: 286 CLPGYKRVNNTFCQ-DINECQLQGVCPNGECLNTMGSYRCTCKIGFGPDPTFSSCVPDPP 344
Query: 277 ECQLQPNACH----NGGTCFNTLGGH----SCVCVNG 305
+ C+ +G C + L H C C G
Sbjct: 345 VISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVG 381
Score = 31.6 bits (70), Expect = 9.5
Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 18/77 (23%)
Query: 173 TCLNTPGSFRCQCPAGYTGPLCE------------NPAVPCAPSPCRNGGTCRQSGDLTY 220
TC T GS + C G T L N V PC NGG C
Sbjct: 38 TC--TKGSCQNSCEKGNTTTLISENGHAADTLTATNFRVVICHLPCMNGGQCSSRDK--- 92
Query: 221 DCACLPGFEGQNCEVNV 237
C C P F G+ C++ V
Sbjct: 93 -CQCPPNFTGKLCQIPV 108
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 219 bits (558), Expect = 2e-56
Identities = 259/1003 (25%), Positives = 366/1003 (36%), Gaps = 198/1003 (19%)
Query: 519 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCS-PDPCHHGRCVDGIASFSCACAPGYTGT 577
GA C P GY+ T C +++++C+ P C HG C++ S+ C C PG++
Sbjct: 338 GADC---PQGYK-----RLNSTHC-QDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLG 388
Query: 578 RCESQVDECRSQPCRHGGKCLDLVD-KYLCRCPSGT--TGVNCEVNIDDCASNPCTFGVC 634
+Q C + C LV ++ C+ P T T C ++ C
Sbjct: 389 PSRTQ---CIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARCQ-RCP 444
Query: 635 RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLP----- 689
DG + +C G + + GE+ F P P
Sbjct: 445 TDGTAAFKEICPAGKGYHILT-----------SHQTLTIQGESDFSLFLHPDGPPKPQQL 493
Query: 690 ---PLCLPP------------------------SHPCAH----EPCSHGICYDAPGGFRC 718
P PP SHP A P I +P R
Sbjct: 494 PESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPELISRPSPPTMRW 553
Query: 719 VCEPGWSGPRCSQSLA-RDACESQPCRAG------GTCSSDGMGFHCTCPPGV----QGR 767
P R + +A E+ CR G C + C C PG Q R
Sbjct: 554 FL-PDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHR 612
Query: 768 QCELLSPCTPNPCEHG-GRCESAPGQLPVCSCPQGWQ-----GPRCQQDVDECAGPAPCG 821
C ++ C PC G G C + G C C +G++ G R D++ECA P CG
Sbjct: 613 YCVDVNECEAEPCGPGRGICMNTGGSYN-CHCNRGYRLHVGAGGRSCVDLNECAKPHLCG 671
Query: 822 PHGICTNLAGSFSCTCHGGY----TGPSCDQDINDC-DPNPCLNGGSCQDGVGSFSC-SC 875
G C N G + C C+ GY + P +DI++C DP+ C + G C++ GSF C +C
Sbjct: 672 DGGFCINFPGHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPD-GKCENKPGSFKCIAC 730
Query: 876 LPGF--AGPRCARDVDECL-SNPCGPGTCTDHVASFTCTCPPGYG----GFHCEQDLPDC 928
PG+ G RDV+EC +PC PG C + SF CTC GY G C D+ +C
Sbjct: 731 QPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVDEC 789
Query: 929 SPSSCFNGGTCVDGVNSFSCLCRPGY----TGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
+ G C + SF C C GY +HC+ + D C GG C + +
Sbjct: 790 EAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCE-DIDECDFPAACIGGDCINTNGSY 848
Query: 985 RCTCLESFT---GPQCQTLVDWCSRQP--CQNGGRC--VQTGAYCLCPPGWSGR------ 1031
RC C + G +CQ +D CS+ P C G C +Q C+C G++
Sbjct: 849 RCLCPQGHRLVGGRKCQD-IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 1032 --------------------LCD---IRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSH 1068
CD ++ +E +G C+ V +
Sbjct: 908 EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEF 967
Query: 1069 YCVCPEGR----------TGSHCEQEVDPCL---AQPCQHGGTCRGYMGGYMCECLPG-- 1113
+ +CP+G+ G +++D C+ ++ C+ G C GY C C G
Sbjct: 968 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKE-GKCVNTQPGYECYCKQGFY 1026
Query: 1114 YNGDNCE-DDVDECASQPCQHGGSCIDLVARYLCSC-PPGTLGVL---C----EINEDDC 1164
Y+G+ E DVDEC + G C + Y C+C PP C E++ D+C
Sbjct: 1027 YDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDEC 1086
Query: 1165 GPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQ 1224
P G CV+L G +RC C P + D S A A RD
Sbjct: 1087 -------QDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCW 1139
Query: 1225 DPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHC------A 1278
G +C +GP T C Q G QCRP P G G HC +
Sbjct: 1140 SQRGE-DGMCAGPLAGP-ALTFDDCCCRQGRGWGAQCRPCPPRGAG----SHCPTSQSES 1193
Query: 1279 QPFWG---------PRCERVA-RSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFP 1328
FW PR E + E +C G C P G C CP G + R+
Sbjct: 1194 NSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSG-RCVPRPGGAVCECPGGFQLDASRARC 1252
Query: 1329 GSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPR 1371
+ C S R + FRC C G+ R
Sbjct: 1253 VDIDECRELNQRGLLC---KSERCVNTSGSFRCVCKAGFARSR 1292
Score = 203 bits (517), Expect = 1e-51
Identities = 211/726 (29%), Positives = 281/726 (38%), Gaps = 113/726 (15%)
Query: 128 CAHGARCSVGPDGRFLCSCPPGY----QGRSCRSDVDECRVGEPCRHG-GTCLNTPGSFR 182
C HG C GP + C C PGY Q R C DV+EC EPC G G C+NT GS+
Sbjct: 585 CGHG-ECVPGPPD-YSCHCNPGYRSHPQHRYC-VDVNECEA-EPCGPGRGICMNTGGSYN 640
Query: 183 CQCPAGYT------GPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN---- 232
C C GY G C + P C +GG C Y C C PG+ +
Sbjct: 641 CHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPG-HYKCNCYPGYRLKASRPP 699
Query: 233 -CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTGQF--CTEDVDECQLQPNACHNG 288
CE ++D+C G C + ++ C C P + Q DV+EC + + C +
Sbjct: 700 VCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECA-EGSPC-SP 756
Query: 289 GTCFNTLGGHSCVCVNGWT----GESCSQNIDDC-ATAVCFHGATCHDRVASFYCACPMG 343
G C N G C C G+ G SC ++D+C A VC +G C + SF C C G
Sbjct: 757 GWCENLPGSFRCTCAQGYAPAPDGRSCL-DVDECEAGDVCDNGI-CSNTPGSFQCQCLSG 814
Query: 344 K--TGLLCHLDDACVSNPCHEDAIC---DTNPVNGRAICTCPPG--FTGGACDQDVDECS 396
+ H +D + C A C D NG C CP G GG QD+DECS
Sbjct: 815 YHLSRDRSHCEDI---DECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKCQDIDECS 871
Query: 397 IGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTC- 455
+ C G C N QGS++C C G+T P + E + P + L+ C
Sbjct: 872 QDPSLCLPHGACKNLQGSYVCVCDEGFT-PTQDQHGCEEVEQPHHKKECYLNFDDTVFCD 930
Query: 456 -ICMAGFTGTYCEVDI-----DECQSSPCVNGGVCKDRVNGFSCTCPSGFS--------- 500
+ T C + D C+ PC + F CP G
Sbjct: 931 SVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAE-----FHSLCPDGKGYTQDNNIVN 985
Query: 501 -GSTCQLDVDEC---ASTPCRNGAKCVDQPDGYECRCAEGF--EGTLCD-RNVDDCSPDP 553
G D+DEC S C+ G KCV+ GYEC C +GF +G L + +VD+C +
Sbjct: 986 YGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDES 1044
Query: 554 -CHHGRCVDGIASFSCACAP----GYTGTRC----ESQVDECRSQPCRHGGKCLDLVDKY 604
C +G C + + CAC P +C E VDEC+ G+C++L Y
Sbjct: 1045 NCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGSY 1104
Query: 605 LCRC----PSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINE 660
C C G +G +C++ P VC D +C GP + +
Sbjct: 1105 RCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGE-DGMCAGPLAGPALTFD-DC 1162
Query: 661 CASSPCGEGGSCVD-GENGFRCLCPPG--------SLPPLCL--PPSHPCAHEP------ 703
C G G C G CP PL L PP + E
Sbjct: 1163 CCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR 1222
Query: 704 CSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGG------TCSSDGMGFH 757
C G C PGG C C PG S++ D E + G C + F
Sbjct: 1223 CVSGRCVPRPGGAVCEC-PGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFR 1281
Query: 758 CTCPPG 763
C C G
Sbjct: 1282 CVCKAG 1287
Score = 167 bits (422), Expect = 1e-40
Identities = 191/724 (26%), Positives = 269/724 (37%), Gaps = 217/724 (29%)
Query: 53 GRCTQLPSREAACLCPPGWVGER----CQLEDPCHSGPCA-GRGVCQSSVVAGTARFSCR 107
G C P + +C C PG+ C + C + PC GRG+C ++ ++C
Sbjct: 588 GECVPGPP-DYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNT----GGSYNCH 642
Query: 108 CPRGFR------GPDCSLPDPCLSSP-CAHGARCSVGPDGRFLCSCPPGYQGRSCR---- 156
C RG+R G C + C C G C P G + C+C PGY+ ++ R
Sbjct: 643 CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP-GHYKCNCYPGYRLKASRPPVC 701
Query: 157 SDVDECRVGEPCRHGGTCLNTPGSFRC-QCPAGYT---GPLCEN-----PAVPCAPSPCR 207
D+DECR C G C N PGSF+C C GY G C + PC+P C
Sbjct: 702 EDIDECRDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCE 760
Query: 208 N------------------GGTCR-----QSGDL-----------TYDCACLPGF----E 229
N G +C ++GD+ ++ C CL G+ +
Sbjct: 761 NLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD 820
Query: 230 GQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWT---GQFCTEDVDECQLQPNACH 286
+CE ++D+C GG C++ +Y C CP G+ C +D+DEC P+ C
Sbjct: 821 RSHCE-DIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGRKC-QDIDECSQDPSLCL 878
Query: 287 NGGTCFNTLGGHSCVCVNGWTG----------------ESCSQNIDDC-------ATAV- 322
G C N G + CVC G+T + C N DD AT V
Sbjct: 879 PHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVT 938
Query: 323 -----CFHGATCHDRV----------ASFYCACPMGKT----------GLLCHLD-DACV 356
C GA D A F+ CP GK G+ H D D C+
Sbjct: 939 QQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECM 998
Query: 357 ---SNPCHEDAICDTNPVNGRAICTCPPGF--TGGACD-QDVDECSIGANPCEHLGRCVN 410
S C E +T P C C GF G + DVDEC +N C + G C N
Sbjct: 999 LFGSEICKEGKCVNTQPGYE---CYCKQGFYYDGNLLECVDVDECLDESN-CRN-GVCEN 1053
Query: 411 TQGSFLCQCG---------RGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCIC---- 457
T+G + C C R P E DV+EC C++ G + C C
Sbjct: 1054 TRGGYRCACTPPAEYSPAQRQCLSPE-EMDVDECQDPAACRPGRCVNLPGSYRCECRPPW 1112
Query: 458 MAGFTGTYCEVDIDECQSSP-----CVN----GGVCKDRVNGFSCT-------------- 494
+ G +G C++ + +P C + G+C + G + T
Sbjct: 1113 VPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGA 1172
Query: 495 ----CPSGFSGSTC----------------------------QLDVDECASTPCRNGAKC 522
CP +GS C + D DEC C +G +C
Sbjct: 1173 QCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECR---CVSG-RC 1228
Query: 523 VDQPDGYECRCAEGFEGTLCDR---NVDDCSPDP-----CHHGRCVDGIASFSCACAPGY 574
V +P G C C GF+ ++D+C C RCV+ SF C C G+
Sbjct: 1229 VPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGF 1288
Query: 575 TGTR 578
+R
Sbjct: 1289 ARSR 1292
Score = 100 bits (249), Expect = 2e-20
Identities = 120/445 (26%), Positives = 160/445 (35%), Gaps = 87/445 (19%)
Query: 45 DGSPCANGGRCTQLPSREAACLCPPGWVGERCQ-----LEDPCHSGPCA----GRGVCQS 95
D S C G C L C+C G+ + Q +E P H C C S
Sbjct: 873 DPSLCLPHGACKNLQG-SYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDS 931
Query: 96 SVVAGTARFSCRCPRGFR-GPDCSL-PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQ-- 151
+ + C C G G C + P P SS H S+ PDG+ GY
Sbjct: 932 VLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFH----SLCPDGK-------GYTQD 980
Query: 152 ------GRSCRSDVDECRV--GEPCRHGGTCLNTPGSFRCQCPAG--YTGPLCENPAVP- 200
G D+DEC + E C+ G C+NT + C C G Y G L E V
Sbjct: 981 NNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCKQGFYYDGNLLECVDVDE 1039
Query: 201 -CAPSPCRNGGTCRQSGDLTYDCACLPGFE----GQNC----EVNVDDCPGHRCLNGGTC 251
S CRNG G Y CAC P E + C E++VD+C G C
Sbjct: 1040 CLDESNCRNGVCENTRGG--YRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRC 1097
Query: 252 VDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNG----GTCFNTLGGHSCVCVNGWT 307
V+ +Y C+C P W D CQL + C++ G +C
Sbjct: 1098 VNLPGSYRCECRPPWVPGPSGRD---CQLPESPAERAPERRDVCWSQRGEDG-MCAGPLA 1153
Query: 308 GESCSQNIDDCATAVCFHGA-------TCHDRVASFYCACPMGKTGLLCHLDDACVSNPC 360
G + + DDC C G C R A +C ++ + P
Sbjct: 1154 GPALT--FDDCC---CRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPP 1208
Query: 361 HEDAICDTN------------PVNGRAICTCPPGFTGGACDQ---DVDEC---SIGANPC 402
++ + + P G A+C CP GF A D+DEC + C
Sbjct: 1209 RDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 1268
Query: 403 EHLGRCVNTQGSFLCQCGRGYTGPR 427
+ RCVNT GSF C C G+ R
Sbjct: 1269 KS-ERCVNTSGSFRCVCKAGFARSR 1292
Score = 57.0 bits (136), Expect = 2e-07
Identities = 64/219 (29%), Positives = 75/219 (34%), Gaps = 66/219 (30%)
Query: 43 CLDGSPCANGGRCTQLPSREAACLCPPGWV----GERCQL-------------------- 78
C D + C GRC LP C C P WV G CQL
Sbjct: 1086 CQDPAAC-RPGRCVNLPG-SYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG 1143
Query: 79 EDPCHSGPCAGRGVCQSSVVAGTAR---FSCR-CPRGFRGPDCSLPDP-----------C 123
ED +GP AG + R CR CP G C
Sbjct: 1144 EDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 1203
Query: 124 LSSP---------------CAHGARCSVGPDGRFLCSCPPGYQGRSCRS---DVDECRV- 164
L P C G RC P G +C CP G+Q + R+ D+DECR
Sbjct: 1204 LGKPPRDEDSSEEDSDECRCVSG-RCVPRPGGA-VCECPGGFQLDASRARCVDIDECREL 1261
Query: 165 ---GEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP 200
G C+ C+NT GSFRC C AG+ VP
Sbjct: 1262 NQRGLLCK-SERCVNTSGSFRCVCKAGFARSRPHGACVP 1299
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 24/121 (19%)
Query: 79 EDPCHSGPCAG---RGVCQSSVVAGTARFSC-RCPRGFRGPDCSLPDPCLSSPCAHGARC 134
+ PC S P G + C S+ + C +CP+ + P P R
Sbjct: 286 KQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQ-LQYTGVQKPGP---------VRG 335
Query: 135 SVGPDGRFLCSCPPGYQGRSCR--SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYT-G 191
VG D CP GY+ + D++EC + CRHG CLN PGS+RC CP G++ G
Sbjct: 336 EVGAD------CPQGYKRLNSTHCQDINECAMPGVCRHGD-CLNNPGSYRCVCPPGHSLG 388
Query: 192 P 192
P
Sbjct: 389 P 389
Score = 46.2 bits (108), Expect = 4e-04
Identities = 87/354 (24%), Positives = 111/354 (31%), Gaps = 92/354 (25%)
Query: 48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVA-GTARFSC 106
PC NGG+C S CLCPP + G CQ+ G G G S A T
Sbjct: 116 PCMNGGQC----SSRNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPP 171
Query: 107 RCPRGFRGPD----------CSLPDPCLSSPCAHGA-RCSVGPDGRFLCSC--------- 146
P G P P P H A +GP G+
Sbjct: 172 LAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGP-GQISAEVQAPPPVVNV 230
Query: 147 ----PPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN---PAV 199
PP + R + P +H L P + P C P
Sbjct: 231 RVHHPPEASVQVHRIESSNAESAAPSQH---LLPHPKPSHPRPPTQKPLGRCFQDTLPKQ 287
Query: 200 PCAPSP----------CRNGGT------CRQSGDLTYDCACLPGFEGQNCEVNVDDCPGH 243
PC +P C + GT C + L Y PG EV D G+
Sbjct: 288 PCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPG--PVRGEVGADCPQGY 345
Query: 244 RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCV 303
+ LN C +D++EC + P C + G C N G + CVC
Sbjct: 346 KRLNSTHC---------------------QDINECAM-PGVCRH-GDCLNNPGSYRCVCP 382
Query: 304 NGWT-GESCSQNIDD-------CATAV-----CFHGATCHDRVASFYCACPMGK 344
G + G S +Q I D C V C H T R+ C C +GK
Sbjct: 383 PGHSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLT--TRLTRQLCCCSVGK 434
Score = 41.6 bits (96), Expect = 0.009
Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 21/148 (14%)
Query: 1094 QHGGTCRGYMGGYMCECLPGY---NGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPP 1150
Q G RG +G +C GY N +C+D ++ECA G C++ Y C CPP
Sbjct: 328 QKPGPVRGEVGA---DCPQGYKRLNSTHCQD-INECAMPGVCRHGDCLNNPGSYRCVCPP 383
Query: 1151 GTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVG-GFRCTCPPGYTGLRCEADINEC 1209
G GP + C LV +C P R + C
Sbjct: 384 G----------HSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHP---LTTRLTRQLCCC 430
Query: 1210 RSGACHAAHTRDCLQDPGGGFRCLCHAG 1237
G A + C D F+ +C AG
Sbjct: 431 SVGKAWGARCQRCPTDGTAAFKEICPAG 458
Score = 39.7 bits (91), Expect = 0.035
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 969 RPCLHGGVCSAAHPGFRCTCL-------ESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY 1021
R CL G + G T + ++ TG + +V PC NGG+C
Sbjct: 73 RTCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVV---CPLPCMNGGQCSSRNQ- 128
Query: 1022 CLCPPGWSGRLCDI 1035
CLCPP ++GR C +
Sbjct: 129 CLCPPDFTGRFCQV 142
Score = 38.1 bits (87), Expect = 0.10
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 18/79 (22%)
Query: 435 CLSGPCRNQA------TCLDRIGQFT-CICMAGFTGTYCEVDIDECQSSPCVNGGVCKDR 487
CL G CR+ T + G T + +GF C + PC+NGG C R
Sbjct: 75 CLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPL--------PCMNGGQCSSR 126
Query: 488 VNGFSCTCPSGFSGSTCQL 506
C CP F+G CQ+
Sbjct: 127 ---NQCLCPPDFTGRFCQV 142
Score = 38.1 bits (87), Expect = 0.10
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 17/77 (22%)
Query: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV------NVDDCPGHRCLNGGTCVDG 254
C CR+ +C+Q ++T L G G + + V CP C+NGG C
Sbjct: 75 CLKGQCRD--SCQQGSNMT-----LIGENGHSTDTLTGSGFRVVVCP-LPCMNGGQCS-- 124
Query: 255 VNTYNCQCPPEWTGQFC 271
+ C CPP++TG+FC
Sbjct: 125 -SRNQCLCPPDFTGRFC 140
Score = 36.6 bits (83), Expect = 0.29
Identities = 53/186 (28%), Positives = 66/186 (35%), Gaps = 48/186 (25%)
Query: 27 LPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSRE------AACLCPPGWVGERCQLED 80
L LLLLL G G G A GG +RE A +C + +C+ D
Sbjct: 28 LLLLLLLLGLGGRVEGGPAGERGAGGGGAL---ARERFKVVFAPVICKRTCLKGQCR--D 82
Query: 81 PCHSGP---CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVG 137
C G G + + G+ GFR C LP C +G +CS
Sbjct: 83 SCQQGSNMTLIGENGHSTDTLTGS---------GFRVVVCPLP-------CMNGGQCS-- 124
Query: 138 PDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENP 197
R C CPP + GR C+V GGT + PG R TG L
Sbjct: 125 --SRNQCLCPPDFTGRF-------CQVPAGGAGGGTGGSGPGLSR-------TGALSTGA 168
Query: 198 AVPCAP 203
P AP
Sbjct: 169 LPPLAP 174
Score = 35.8 bits (81), Expect = 0.50
Identities = 75/299 (25%), Positives = 90/299 (30%), Gaps = 70/299 (23%)
Query: 639 NRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHP 698
+R C+C P FTG C V P G G G L G+L LPP P
Sbjct: 125 SRNQCLCPPDFTGRFCQV--------PAGGAGGGTGGSGPG--LSRTGALSTGALPPLAP 174
Query: 699 CAHEPCSHGICY------DAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSD 752
S Y D PG PG GP + A
Sbjct: 175 EGDSVASKHAIYAVQVIADPPG-------PG-EGPPAQHAAFLVPLGPGQISAEVQAPPP 226
Query: 753 GMGFHCTCPP--GVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQD 810
+ PP VQ + E + + P +H P P G RC QD
Sbjct: 227 VVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLG----RCFQD 282
Query: 811 V---DEC-AGPAP--------CGPHGI---------CTNLA-----------GSFSCTCH 838
C + P P CG G C L G C
Sbjct: 283 TLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCP 342
Query: 839 GGY---TGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA-GP---RCARDVDE 890
GY C QDIN+C G C + GS+ C C PG + GP +C D E
Sbjct: 343 QGYKRLNSTHC-QDINECAMPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCIADKPE 400
Score = 35.8 bits (81), Expect = 0.50
Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 25/106 (23%)
Query: 495 CPSGFS--GSTCQLDVDECASTP-CRNGAKCVDQPDGYECRCAEGF-------------- 537
CP G+ ST D++ECA CR+G C++ P Y C C G
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHG-DCLNNPGSYRCVCPPGHSLGPSRTQCIADKP 399
Query: 538 -EGTLCDRNVDDCSPD-PCHHGRCVDGIASFSCACAPGYT-GTRCE 580
E +LC R V SP+ C H + C C+ G G RC+
Sbjct: 400 EEKSLCFRLV---SPEHQCQH-PLTTRLTRQLCCCSVGKAWGARCQ 441
Score = 35.0 bits (79), Expect = 0.86
Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 11/91 (12%)
Query: 704 CSHGICYDA---PGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTC 760
C G C D+ + E G S + S R PC GG CSS C C
Sbjct: 75 CLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQCSSRNQ---CLC 131
Query: 761 PPGVQGRQCELLSPCTPNPCEHGGRCESAPG 791
PP GR C++ P GG S PG
Sbjct: 132 PPDFTGRFCQV-----PAGGAGGGTGGSGPG 157
Score = 33.9 bits (76), Expect = 1.9
Identities = 37/130 (28%), Positives = 48/130 (36%), Gaps = 28/130 (21%)
Query: 2141 GGPGRAGLGRQPPGGCVLSLGLLNPVAVPLD--------WARLPPPAPPGP--------- 2183
GG G +G G G LS G L P+A D +A PPGP
Sbjct: 149 GGTGGSGPGLSRTGA--LSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHA 206
Query: 2184 SFLLPLAPGPQLLNPGTPVSPQ-ERPPPYLAVPGHGEEYPAAGAHSSPPKARFLRVPSEH 2242
+FL+PL PG +S + + PPP + V H + H PS+H
Sbjct: 207 AFLVPLGPGQ--------ISAEVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQH 258
Query: 2243 PYLTPSPESP 2252
P P P
Sbjct: 259 LLPHPKPSHP 268
Score = 33.5 bits (75), Expect = 2.5
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 10/72 (13%)
Query: 412 QGSFLCQCGRGY---TGPRCETDVNEC-LSGPCRNQATCLDRIGQFTCICMAGF----TG 463
+G C +GY C+ D+NEC + G CR+ CL+ G + C+C G +
Sbjct: 334 RGEVGADCPQGYKRLNSTHCQ-DINECAMPGVCRH-GDCLNNPGSYRCVCPPGHSLGPSR 391
Query: 464 TYCEVDIDECQS 475
T C D E +S
Sbjct: 392 TQCIADKPEEKS 403
Score = 33.1 bits (74), Expect = 3.3
Identities = 15/37 (40%), Positives = 17/37 (45%), Gaps = 4/37 (10%)
Query: 199 VPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEV 235
V P PC NGG C C C P F G+ C+V
Sbjct: 110 VVVCPLPCMNGGQCSSRN----QCLCPPDFTGRFCQV 142
Score = 33.1 bits (74), Expect = 3.3
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 4/51 (7%)
Query: 1130 PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNG 1180
PC +GG C +R C CPP G C++ G G SGP G
Sbjct: 116 PCMNGGQCS---SRNQCLCPPDFTGRFCQVPAGGAGGGTG-GSGPGLSRTG 162
Score = 32.7 bits (73), Expect = 4.3
Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 2/83 (2%)
Query: 2196 LNPGTPVSPQERPPPYLAVPGHGEEYPAAGAHSSPPKARFLRVPSEHPYLTPSPES--PE 2253
L+P P PQ+ P P + G + P + V HP T +P PE
Sbjct: 482 LHPDGPPKPQQLPESPSQAPPPEDTEEERGVTTDSPVSEERSVQQSHPTATTTPARPYPE 541
Query: 2254 HWASPSPPSLSDWSESTPSPATA 2276
+ PSPP++ + P +A
Sbjct: 542 LISRPSPPTMRWFLPDLPPSRSA 564
Score = 32.3 bits (72), Expect = 5.6
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 930 PSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQ 960
P C NGG C + CLC P +TG CQ
Sbjct: 114 PLPCMNGGQCS---SRNQCLCPPDFTGRFCQ 141
Score = 32.3 bits (72), Expect = 5.6
Identities = 49/199 (24%), Positives = 74/199 (37%), Gaps = 28/199 (14%)
Query: 386 GACDQD-VDECSIGANPCEHLGRCVNTQGSFLCQCGRG--YTGPRCE-TDVNECLSGPCR 441
G C QD + + G+NP L + + GS G+ + P+ + T V + GP R
Sbjct: 277 GRCFQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQK--PGPVR 334
Query: 442 NQATCLDRIGQFTCICMAGF---TGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG 498
G+ C G+ T+C+ DI+EC G C + + C CP G
Sbjct: 335 ---------GEVGADCPQGYKRLNSTHCQ-DINECAMPGVCRHGDCLNNPGSYRCVCPPG 384
Query: 499 FSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGR 558
S + +C + + C + E +C T R + CS R
Sbjct: 385 HSLGPSR---TQCIADKPEEKSLCF-RLVSPEHQCQHPLT-TRLTRQLCCCSVGKAWGAR 439
Query: 559 C----VDGIASFSCACAPG 573
C DG A+F C G
Sbjct: 440 CQRCPTDGTAAFKEICPAG 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.482
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 131,827,554
Number of Sequences: 37866
Number of extensions: 8863796
Number of successful extensions: 93744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 712
Number of HSP's successfully gapped in prelim test: 1482
Number of HSP's that attempted gapping in prelim test: 30683
Number of HSP's gapped (non-prelim): 25981
length of query: 2321
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2202
effective length of database: 13,741,464
effective search space: 30258703728
effective search space used: 30258703728
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.