Search of human proteins with 50659091

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50659091 scavenger receptor cysteine-rich type 1 precursor
[Homo sapiens]
         (1453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...  3139   0.0  
gi|44662834 CD163 antigen isoform a [Homo sapiens]                   1324   0.0  
gi|44889963 CD163 antigen isoform b [Homo sapiens]                   1321   0.0  
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...  1108   0.0  
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...  1101   0.0  
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]     856   0.0  
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...   855   0.0  
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]     747   0.0  
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            327   7e-89
gi|18152779 scavenger receptor cysteine rich domain containing, ...   324   3e-88
gi|4506143 neurotrypsin precursor [Homo sapiens]                      306   7e-83
gi|5174411 CD5 molecule-like [Homo sapiens]                           265   3e-70
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           235   2e-61
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             226   2e-58
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             220   7e-57
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              206   1e-52
gi|194018748 CD6 molecule [Homo sapiens]                              199   2e-50
gi|5031863 galectin 3 binding protein [Homo sapiens]                  120   7e-27
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo...   115   3e-25
gi|5803080 macrophage receptor with collagenous structure [Homo ...   114   9e-25
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]       114   9e-25
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]             108   3e-23
gi|166197668 CD5 molecule [Homo sapiens]                               81   6e-15
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo...    57   1e-07
gi|119392081 complement factor I preproprotein [Homo sapiens]          50   2e-05
gi|223942069 enterokinase precursor [Homo sapiens]                     41   0.010
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...    40   0.013
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap...    40   0.013
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...    38   0.062
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...    38   0.062

>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score = 3139 bits (8138), Expect = 0.0
 Identities = 1453/1453 (100%), Positives = 1453/1453 (100%)

Query: 1    MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT 60
            MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT
Sbjct: 1    MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT 60

Query: 61   VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN 120
            VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN
Sbjct: 61   VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN 120

Query: 121  ESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTIC 180
            ESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTIC
Sbjct: 121  ESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTIC 180

Query: 181  DDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWG 240
            DDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWG
Sbjct: 181  DDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWG 240

Query: 241  NHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVC 300
            NHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVC
Sbjct: 241  NHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVC 300

Query: 301  KQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVI 360
            KQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVI
Sbjct: 301  KQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVI 360

Query: 361  CSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSR 420
            CSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSR
Sbjct: 361  CSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSR 420

Query: 421  RAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVG 480
            RAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVG
Sbjct: 421  RAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVG 480

Query: 481  AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWL 540
            AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWL
Sbjct: 481  AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWL 540

Query: 541  DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYF 600
            DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYF
Sbjct: 541  DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYF 600

Query: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLW 660
            QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLW
Sbjct: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLW 660

Query: 661  SCRNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWG 720
            SCRNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWG
Sbjct: 661  SCRNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWG 720

Query: 721  MNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACH 780
            MNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACH
Sbjct: 721  MNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACH 780

Query: 781  LNMEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840
            LNMEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD
Sbjct: 781  LNMEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840

Query: 841  AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV 900
            AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV
Sbjct: 841  AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV 900

Query: 901  RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV 960
            RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV
Sbjct: 901  RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV 960

Query: 961  RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS 1020
            RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS
Sbjct: 961  RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS 1020

Query: 1021 AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080
            AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG
Sbjct: 1021 AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080

Query: 1081 VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA 1140
            VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA
Sbjct: 1081 VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA 1140

Query: 1141 LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT 1200
            LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT
Sbjct: 1141 LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT 1200

Query: 1201 GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVE 1260
            GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVE
Sbjct: 1201 GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVE 1260

Query: 1261 IWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNES 1320
            IWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNES
Sbjct: 1261 IWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNES 1320

Query: 1321 FLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALILSSIFGLLLLVLFILFL 1380
            FLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALILSSIFGLLLLVLFILFL
Sbjct: 1321 FLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALILSSIFGLLLLVLFILFL 1380

Query: 1381 TWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGCEDASDT 1440
            TWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGCEDASDT
Sbjct: 1381 TWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGCEDASDT 1440

Query: 1441 SLLGVLPASEATK 1453
            SLLGVLPASEATK
Sbjct: 1441 SLLGVLPASEATK 1453


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score = 1324 bits (3427), Expect = 0.0
 Identities = 608/1102 (55%), Positives = 774/1102 (70%), Gaps = 17/1102 (1%)

Query: 364  GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAK 423
            G D ELRL DG N CSGRVEV++ E+W T+C+  W  E   V+C QLGCP ++     A 
Sbjct: 46   GTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWAN 105

Query: 424  PSNEARDIWINSISCTGNESALWDCTYDGKAKRT-CFRRSDAGVICSDKADLDLRLVGAH 482
             S  +  IW++ +SC GNESALWDC +DG  K + C  + DAGV CSD ++L++RL    
Sbjct: 106  SSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGG 165

Query: 483  SPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDD 542
            + C GR+E+K+QG WGTVC D ++  +A+V+C+QL CG  +   G + F E SGPIW DD
Sbjct: 166  NMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDD 225

Query: 543  VSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQG 602
            + C GNES +W+C+H GWGKHNC H ED  V CS  A   LRLV G   CSGRLEV FQG
Sbjct: 226  LICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQG 285

Query: 603  RWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSC 662
             WGT+CDDGW+S  AAV C QL CP+++  +G  NAS G+G IWLD VSC G E  +W C
Sbjct: 286  EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345

Query: 663  RNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMN 722
            ++  WG + C+H+ED GV CSD SD+ELRL GG SRCAG VEV +Q  +G +C  GWG+ 
Sbjct: 346  KHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK 405

Query: 723  IAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLN 782
             A+VVCRQL CGSA++ S + +   +  +  +  S C G E SLWDC  W+W    C   
Sbjct: 406  EADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHY 465

Query: 783  MEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842
             EA + CSAHR+PRLVG D+PCSGRVEVKH DTW S+CDSDFSL AA+VLCREL CG  +
Sbjct: 466  EEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525

Query: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRL 902
            S+  G HFG+GNG  WAE+FQCEG E+HL+LCP+   PE TC HSR+VGVVCSRYT++RL
Sbjct: 526  SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRL 585

Query: 903  VNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRV 962
            VNGK+ C+G+VE+  LG WGSLC++HWD EDA VLC+QL CG ALST GG   G+ + ++
Sbjct: 586  VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645

Query: 963  WGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAV 1022
            W H FHC G E  + +C +T LGA  C      SVIC+G+ +Q L  C ++   P    +
Sbjct: 646  WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTI 705

Query: 1023 PEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVA 1082
            PE SA+ C+E  +LRLV+G  RCAGRVEIYH+G WGTICDD WDLSDAHVVC++LGCG A
Sbjct: 706  PEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEA 765

Query: 1083 FNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALR 1142
             NAT SAHFGEG+GPIWLD++ C G ES +WQC S GWGQ +CRHKEDAGVICSEF +LR
Sbjct: 766  INATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLR 825

Query: 1143 LYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGS 1202
            L SE   E+CAGRLEVFYNG WG+VG+ +++    G+VCRQLGC + G ++ A L K  S
Sbjct: 826  LTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMS 885

Query: 1203 GFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVEIW 1262
              MWVD++QCPK   ++WQC S+PWE+R++SP+EETWITC+++IR++ G T CSGRVEIW
Sbjct: 886  IPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIW 945

Query: 1263 HAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFL 1322
            H GSWGTVCDDSWDL +A+VVCQQLGCG AL A ++A FGQGTG IWL++++CKGNES L
Sbjct: 946  HGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSL 1005

Query: 1323 WDCHAKPWGQSDCGHKEDAGVRCSGQSLK------SLNASSGHLALILSSIFGLLLLVLF 1376
            WDC A+ WG S+CGHKEDA V C+  S++      +   SS   + I   I G++LL +F
Sbjct: 1006 WDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIF 1065

Query: 1377 I--LFLTWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGC 1434
            +   FLT  R Q+Q+   L VS+R    + +  + EM +CL  +D     +S++  +H  
Sbjct: 1066 VALFFLTKKRRQRQR---LAVSSRGENLVHQIQYREMNSCLNADDLDLMNSSEN--SHES 1120

Query: 1435 EDASDTSLLGV---LPASEATK 1453
             D S   L+ V   LP S   K
Sbjct: 1121 ADFSAAELISVSKFLPISGMEK 1142



 Score =  785 bits (2026), Expect = 0.0
 Identities = 404/1032 (39%), Positives = 556/1032 (53%), Gaps = 40/1032 (3%)

Query: 1    MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT 60
            M+L ++S   DF R     NL    +T +LLL++CF+ SS  GTD ELRLV+G+  CSG 
Sbjct: 6    MVLLEDSGSADFRRHFV--NLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGR 63

Query: 61   VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN 120
            VEVK Q +WGTVC++GW+  A +V+C QLGCP +     +  +    G+IW+D VSC GN
Sbjct: 64   VEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGN 123

Query: 121  ESALWECQHREWGSH-NCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTI 179
            ESALW+C+H  WG H NC H +D GV C   +NL +RL  G N CSGR+E+KFQ RWGT+
Sbjct: 124  ESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTV 183

Query: 180  CDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGW 239
            CDD +N++ A+V+CRQL C S+   SG  N      PIW DD++C GNE ALWNC+H+GW
Sbjct: 184  CDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGW 243

Query: 240  GNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVV 299
            G H+C H ED  + C   +DL LRLV G   C GR+E++ QG WGT+C   W++  A V 
Sbjct: 244  GKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 300  CKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSV 359
            CKQLGC TA+   G  +   G   +WLD VSC G+E  +W C+H       C H  D  V
Sbjct: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 360  ICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGS 419
             CSDG+DLELRL  G + C+G VEV I      +CD+ W  ++A VVC+QLGC  ++  S
Sbjct: 364  TCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423

Query: 420  RRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLV 479
             +     +A + W+   SC GNE++LWDC        TC    +A + CS  A  + RLV
Sbjct: 424  YQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS--AHREPRLV 481

Query: 480  GAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIW 539
            G   PC GR+EVK+   WG++C   +S   A+V+C++L CG  + + G  +F E +G IW
Sbjct: 482  GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541

Query: 540  LDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVY 599
             ++  C G+ES++  C  +   +  C H  DV V CS      +RLV G   C GR+E+ 
Sbjct: 542  AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--IRLVNGKTPCEGRVELK 599

Query: 600  FQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDL 659
              G WG++C+  W+ + A V+C QL C  ++   G      G G+IW     C G E  +
Sbjct: 600  TLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHM 659

Query: 660  WSCRNSGWGNNDCSHSEDVGVICSDASDM-----------------------------EL 690
              C  +  G + C   +   VICS                                  +L
Sbjct: 660  GDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719

Query: 691  RLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTL 750
            RLV G  RCAG+VE+  +G+ G +C + W ++ A VVCRQL CG AI  +   HF E T 
Sbjct: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779

Query: 751  HILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLV--GADMPCSGRV 808
             I +    C G E+ +W C    W Q  C    +A +ICS     RL    +   C+GR+
Sbjct: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRL 839

Query: 809  EVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSE 868
            EV +   W +V  S  S     V+CR+L C D   ++        +   W +  QC    
Sbjct: 840  EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899

Query: 869  THLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTH 928
              L  CP     +     S E  + C     +RL  G + C G+VEI   G WG++CD  
Sbjct: 900  DTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDS 957

Query: 929  WDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPP 988
            WD +DA+V+C+QL CG AL        G+ +  +W +   C GNES L +C     G   
Sbjct: 958  WDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSE 1017

Query: 989  CIHGNTVSVICT 1000
            C H    +V CT
Sbjct: 1018 CGHKEDAAVNCT 1029



 Score =  255 bits (652), Expect = 2e-67
 Identities = 127/320 (39%), Positives = 171/320 (53%), Gaps = 10/320 (3%)

Query: 47   ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSF---AMFRFGQA 103
            +LRLVNG G C+G VE+  +G WGT+CDD W+ + + VVC+QLGC  +        FG+ 
Sbjct: 718  QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG 777

Query: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNS 163
                G IWLD++ C G ES +W+C    WG  NC H ED GV C    +L L       +
Sbjct: 778  T---GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREA 834

Query: 164  CSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDIL 223
            C+GR+EV +   WGT+     +  T  VVCRQLGC      +      A+  P+W+D++ 
Sbjct: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 224  CQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRW 283
            C      LW C    W     S +E+  +TC    D ++RL  G   C GRVE+   G W
Sbjct: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITC----DNKIRLQEGPTSCSGRVEIWHGGSW 950

Query: 284  GTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRH 343
            GTVC   W+   A VVC+QLGCG AL          G+  +WL+ V C GNES LWDC  
Sbjct: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010

Query: 344  SGTVNFDCLHQNDVSVICSD 363
                + +C H+ D +V C+D
Sbjct: 1011 RRWGHSECGHKEDAAVNCTD 1030



 Score =  156 bits (394), Expect = 2e-37
 Identities = 74/202 (36%), Positives = 105/202 (51%), Gaps = 4/202 (1%)

Query: 57   CSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVS 116
            C+G +EV + G WGTV     + T   VVC+QLGC     +            +W+D+V 
Sbjct: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 117  CYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERW 176
            C      LW+C    W        E+  + C  +    +RL +G  SCSGRVE+     W
Sbjct: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITCDNK----IRLQEGPTSCSGRVEIWHGGSW 950

Query: 177  GTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRH 236
            GT+CDD W+L+ A VVC+QLGC  +  +           PIWL+++ C+GNE +LW+C  
Sbjct: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010

Query: 237  RGWGNHDCSHNEDVTLTCYDSS 258
            R WG+ +C H ED  + C D S
Sbjct: 1011 RRWGHSECGHKEDAAVNCTDIS 1032


>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score = 1321 bits (3419), Expect = 0.0
 Identities = 598/1065 (56%), Positives = 759/1065 (71%), Gaps = 12/1065 (1%)

Query: 364  GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAK 423
            G D ELRL DG N CSGRVEV++ E+W T+C+  W  E   V+C QLGCP ++     A 
Sbjct: 46   GTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWAN 105

Query: 424  PSNEARDIWINSISCTGNESALWDCTYDGKAKRT-CFRRSDAGVICSDKADLDLRLVGAH 482
             S  +  IW++ +SC GNESALWDC +DG  K + C  + DAGV CSD ++L++RL    
Sbjct: 106  SSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGG 165

Query: 483  SPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDD 542
            + C GR+E+K+QG WGTVC D ++  +A+V+C+QL CG  +   G + F E SGPIW DD
Sbjct: 166  NMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDD 225

Query: 543  VSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQG 602
            + C GNES +W+C+H GWGKHNC H ED  V CS  A   LRLV G   CSGRLEV FQG
Sbjct: 226  LICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQG 285

Query: 603  RWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSC 662
             WGT+CDDGW+S  AAV C QL CP+++  +G  NAS G+G IWLD VSC G E  +W C
Sbjct: 286  EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQC 345

Query: 663  RNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMN 722
            ++  WG + C+H+ED GV CSD SD+ELRL GG SRCAG VEV +Q  +G +C  GWG+ 
Sbjct: 346  KHHEWGKHYCNHNEDAGVTCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLK 405

Query: 723  IAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLN 782
             A+VVCRQL CGSA++ S + +   +  +  +  S C G E SLWDC  W+W    C   
Sbjct: 406  EADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHY 465

Query: 783  MEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842
             EA + CSAHR+PRLVG D+PCSGRVEVKH DTW S+CDSDFSL AA+VLCREL CG  +
Sbjct: 466  EEAKITCSAHREPRLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVV 525

Query: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRL 902
            S+  G HFG+GNG  WAE+FQCEG E+HL+LCP+   PE TC HSR+VGVVCSRYT++RL
Sbjct: 526  SILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTEIRL 585

Query: 903  VNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRV 962
            VNGK+ C+G+VE+  LG WGSLC++HWD EDA VLC+QL CG ALST GG   G+ + ++
Sbjct: 586  VNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQI 645

Query: 963  WGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAV 1022
            W H FHC G E  + +C +T LGA  C      SVIC+G+ +Q L  C ++   P    +
Sbjct: 646  WRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTI 705

Query: 1023 PEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVA 1082
            PE SA+ C+E  +LRLV+G  RCAGRVEIYH+G WGTICDD WDLSDAHVVC++LGCG A
Sbjct: 706  PEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEA 765

Query: 1083 FNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALR 1142
             NAT SAHFGEG+GPIWLD++ C G ES +WQC S GWGQ +CRHKEDAGVICSEF +LR
Sbjct: 766  INATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLR 825

Query: 1143 LYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGS 1202
            L SE   E+CAGRLEVFYNG WG+VG+ +++    G+VCRQLGC + G ++ A L K  S
Sbjct: 826  LTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMS 885

Query: 1203 GFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVEIW 1262
              MWVD++QCPK   ++WQC S+PWE+R++SP+EETWITC+++IR++ G T CSGRVEIW
Sbjct: 886  IPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQEGPTSCSGRVEIW 945

Query: 1263 HAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFL 1322
            H GSWGTVCDDSWDL +A+VVCQQLGCG AL A ++A FGQGTG IWL++++CKGNES L
Sbjct: 946  HGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSL 1005

Query: 1323 WDCHAKPWGQSDCGHKEDAGVRCSGQSLK------SLNASSGHLALILSSIFGLLLLVLF 1376
            WDC A+ WG S+CGHKEDA V C+  S++      +   SS   + I   I G++LL +F
Sbjct: 1006 WDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKATTGRSSRQSSFIAVGILGVVLLAIF 1065

Query: 1377 I--LFLTWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKRED 1419
            +   FLT  R Q+Q+   L VS+R    + +  + EM +CL  +D
Sbjct: 1066 VALFFLTKKRRQRQR---LAVSSRGENLVHQIQYREMNSCLNADD 1107



 Score =  785 bits (2026), Expect = 0.0
 Identities = 404/1032 (39%), Positives = 556/1032 (53%), Gaps = 40/1032 (3%)

Query: 1    MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT 60
            M+L ++S   DF R     NL    +T +LLL++CF+ SS  GTD ELRLV+G+  CSG 
Sbjct: 6    MVLLEDSGSADFRRHFV--NLSPFTITVVLLLSACFVTSSLGGTDKELRLVDGENKCSGR 63

Query: 61   VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN 120
            VEVK Q +WGTVC++GW+  A +V+C QLGCP +     +  +    G+IW+D VSC GN
Sbjct: 64   VEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGN 123

Query: 121  ESALWECQHREWGSH-NCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTI 179
            ESALW+C+H  WG H NC H +D GV C   +NL +RL  G N CSGR+E+KFQ RWGT+
Sbjct: 124  ESALWDCKHDGWGKHSNCTHQQDAGVTCSDGSNLEMRLTRGGNMCSGRIEIKFQGRWGTV 183

Query: 180  CDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGW 239
            CDD +N++ A+V+CRQL C S+   SG  N      PIW DD++C GNE ALWNC+H+GW
Sbjct: 184  CDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGW 243

Query: 240  GNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVV 299
            G H+C H ED  + C   +DL LRLV G   C GR+E++ QG WGT+C   W++  A V 
Sbjct: 244  GKHNCDHAEDAGVICSKGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 300  CKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSV 359
            CKQLGC TA+   G  +   G   +WLD VSC G+E  +W C+H       C H  D  V
Sbjct: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 360  ICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGS 419
             CSDG+DLELRL  G + C+G VEV I      +CD+ W  ++A VVC+QLGC  ++  S
Sbjct: 364  TCSDGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423

Query: 420  RRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLV 479
             +     +A + W+   SC GNE++LWDC        TC    +A + CS  A  + RLV
Sbjct: 424  YQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS--AHREPRLV 481

Query: 480  GAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIW 539
            G   PC GR+EVK+   WG++C   +S   A+V+C++L CG  + + G  +F E +G IW
Sbjct: 482  GGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIW 541

Query: 540  LDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVY 599
             ++  C G+ES++  C  +   +  C H  DV V CS      +RLV G   C GR+E+ 
Sbjct: 542  AEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--IRLVNGKTPCEGRVELK 599

Query: 600  FQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDL 659
              G WG++C+  W+ + A V+C QL C  ++   G      G G+IW     C G E  +
Sbjct: 600  TLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHM 659

Query: 660  WSCRNSGWGNNDCSHSEDVGVICSDASDM-----------------------------EL 690
              C  +  G + C   +   VICS                                  +L
Sbjct: 660  GDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQL 719

Query: 691  RLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTL 750
            RLV G  RCAG+VE+  +G+ G +C + W ++ A VVCRQL CG AI  +   HF E T 
Sbjct: 720  RLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG 779

Query: 751  HILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLV--GADMPCSGRV 808
             I +    C G E+ +W C    W Q  C    +A +ICS     RL    +   C+GR+
Sbjct: 780  PIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREACAGRL 839

Query: 809  EVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSE 868
            EV +   W +V  S  S     V+CR+L C D   ++        +   W +  QC    
Sbjct: 840  EVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGP 899

Query: 869  THLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTH 928
              L  CP     +     S E  + C     +RL  G + C G+VEI   G WG++CD  
Sbjct: 900  DTLWQCPSSPWEKRLASPSEETWITCD--NKIRLQEGPTSCSGRVEIWHGGSWGTVCDDS 957

Query: 929  WDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPP 988
            WD +DA+V+C+QL CG AL        G+ +  +W +   C GNES L +C     G   
Sbjct: 958  WDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSE 1017

Query: 989  CIHGNTVSVICT 1000
            C H    +V CT
Sbjct: 1018 CGHKEDAAVNCT 1029



 Score =  255 bits (652), Expect = 2e-67
 Identities = 127/320 (39%), Positives = 171/320 (53%), Gaps = 10/320 (3%)

Query: 47   ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSF---AMFRFGQA 103
            +LRLVNG G C+G VE+  +G WGT+CDD W+ + + VVC+QLGC  +        FG+ 
Sbjct: 718  QLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEG 777

Query: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNS 163
                G IWLD++ C G ES +W+C    WG  NC H ED GV C    +L L       +
Sbjct: 778  T---GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMSLRLTSEASREA 834

Query: 164  CSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDIL 223
            C+GR+EV +   WGT+     +  T  VVCRQLGC      +      A+  P+W+D++ 
Sbjct: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 224  CQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRW 283
            C      LW C    W     S +E+  +TC    D ++RL  G   C GRVE+   G W
Sbjct: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITC----DNKIRLQEGPTSCSGRVEIWHGGSW 950

Query: 284  GTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRH 343
            GTVC   W+   A VVC+QLGCG AL          G+  +WL+ V C GNES LWDC  
Sbjct: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010

Query: 344  SGTVNFDCLHQNDVSVICSD 363
                + +C H+ D +V C+D
Sbjct: 1011 RRWGHSECGHKEDAAVNCTD 1030



 Score =  156 bits (394), Expect = 2e-37
 Identities = 74/202 (36%), Positives = 105/202 (51%), Gaps = 4/202 (1%)

Query: 57   CSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVS 116
            C+G +EV + G WGTV     + T   VVC+QLGC     +            +W+D+V 
Sbjct: 835  CAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQ 894

Query: 117  CYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERW 176
            C      LW+C    W        E+  + C  +    +RL +G  SCSGRVE+     W
Sbjct: 895  CPKGPDTLWQCPSSPWEKRLASPSEETWITCDNK----IRLQEGPTSCSGRVEIWHGGSW 950

Query: 177  GTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRH 236
            GT+CDD W+L+ A VVC+QLGC  +  +           PIWL+++ C+GNE +LW+C  
Sbjct: 951  GTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPA 1010

Query: 237  RGWGNHDCSHNEDVTLTCYDSS 258
            R WG+ +C H ED  + C D S
Sbjct: 1011 RRWGHSECGHKEDAAVNCTDIS 1032


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 1108 bits (2865), Expect = 0.0
 Identities = 611/1522 (40%), Positives = 785/1522 (51%), Gaps = 214/1522 (14%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQA 103
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     Q 
Sbjct: 230  SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289

Query: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG-------------- 149
                G I LDDV C G+ES LW C H  W +HNC H ED GV C                
Sbjct: 290  GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPT 349

Query: 150  --------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSS 201
                    E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC  +
Sbjct: 350  SHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA 409

Query: 202  FISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS---- 257
              + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C D+    
Sbjct: 410  TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLPTI 469

Query: 258  ----------SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT 307
                      S L LRLV G +RC GRVE+  +G WGTVC   W+   A+VVC+QLGCG 
Sbjct: 470  TLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 529

Query: 308  ALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDG-AD 366
            A+   G      GS  + LD V CSGNES+LW C H+G ++ +C H  D  VICS   + 
Sbjct: 530  AMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESS 589

Query: 367  LELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSN 426
            L LRL +G + C GRVEV     W T+CD +W    A VVC+QLGC ++      A+   
Sbjct: 590  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQ 649

Query: 427  EARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS----------------- 469
             +  I ++ + C+G+ES LW C  +G     C    DAGVICS                 
Sbjct: 650  GSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTIT 709

Query: 470  -------DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKP 522
                    ++ L LRLV     C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  
Sbjct: 710  LPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 769

Query: 523  MHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS------ 576
                G   F + SGPI LDDV C G+ES +W C H+GW  HNC H ED  V CS      
Sbjct: 770  TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRP 829

Query: 577  --GDATW--------------GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVV 620
                 TW               LRLV G +RC GR+EV ++G WGTVCDD W++  A VV
Sbjct: 830  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 889

Query: 621  CSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGV 680
            C QL C  +    G      G G I LDDV C G ES LWSC ++GW +++C HSED GV
Sbjct: 890  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 949

Query: 681  ICSDA------------------------SDMELRLVGGSSRCAGKVEVNVQGAVGILCA 716
            ICS A                        S + LRLV G  RC G+VEV  QG+ G +C 
Sbjct: 950  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 1009

Query: 717  NGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQ 776
            + W  N A VVCRQL CG A+       F + +  I++ +  C+G E+ LW C    W  
Sbjct: 1010 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 1069

Query: 777  TACHLNMEASLICSAHRQP------------------------RLVGADMPCSGRVEVKH 812
              C  + +A +ICSA +                          RLV     C GRVEV +
Sbjct: 1070 HNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY 1129

Query: 813  ADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLA 872
              +W +VCD  +  + ANV+CR+L CG A+S      FG+G+G    +  +C G E++L 
Sbjct: 1130 RGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLW 1189

Query: 873  LCPIVQHPEDTCIHSREVGVVCSRYTD------------------------VRLVNGKSQ 908
             CP        C H  + GV+CS                            +RLVNG  +
Sbjct: 1190 SCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR 1249

Query: 909  CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFH 968
            C G+VE+   G WG++CD +WD  DA V+CRQL CG A S  G    G+ S  +      
Sbjct: 1250 CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 1309

Query: 969  CLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSAL 1028
            C G+ES L +C      +  C H     VIC+ S +QP  P        + S     S+L
Sbjct: 1310 CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT-PSPDTWPTSHASTAGSESSL 1368

Query: 1029 ICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVS 1088
                   LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +
Sbjct: 1369 A------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1422

Query: 1089 AHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS------------ 1136
            A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS            
Sbjct: 1423 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1482

Query: 1137 ----------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC 1186
                        + L L      + C GR+EV Y G+WG+V      T  A +VCRQLGC
Sbjct: 1483 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGC 1542

Query: 1187 GENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ER 1229
            G             GSG + +DD++C      +W C    W                  +
Sbjct: 1543 GWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQ 1602

Query: 1230 RISSPAEETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDL 1277
              S+P  +TW+T          E  + +R   GGD  C GRVE+ + GSWGTVCDDSWD 
Sbjct: 1603 SQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDT 1661

Query: 1278 AEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGH 1337
             +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  K W   +CGH
Sbjct: 1662 NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGH 1721

Query: 1338 KEDAGVRCSGQSLKSLNASSGH 1359
             EDAGV CS   + S      H
Sbjct: 1722 HEDAGVICSATQINSTTTDWWH 1743



 Score = 1105 bits (2857), Expect = 0.0
 Identities = 604/1524 (39%), Positives = 787/1524 (51%), Gaps = 219/1524 (14%)

Query: 38   ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97
            ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 98   ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149
                 FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 152  PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208

Query: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                                E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 209  TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268

Query: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 269  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328

Query: 250  VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
              + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 329  AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388

Query: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 389  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 348  NFDCLHQNDVSVICSD--------------GADLELRLADGSNNCSGRVEVRIHEQWWTI 393
            + +C H  D  VICSD               + L LRL +G + C GRVEV     W T+
Sbjct: 449  SHNCQHSEDAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTV 508

Query: 394  CDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGK 453
            CD +W    A VVC+QLGC +++     A+    +  I ++ + C+GNES LW C ++G 
Sbjct: 509  CDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGW 568

Query: 454  AKRTCFRRSDAGVICS-DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAV 512
                C    DAGVICS  ++ L LRLV     C GR+EV Y+G WGTVC D W T +A V
Sbjct: 569  LSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 628

Query: 513  VCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVI 572
            VC+QLGCG      G   F + SGPI LDDV C G+ES +W C ++GW  HNC H ED  
Sbjct: 629  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAG 688

Query: 573  VTCS------------------------GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVC 608
            V CS                         +++  LRLV GS+RC GR+EV ++G WGTVC
Sbjct: 689  VICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVC 748

Query: 609  DDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWG 668
            DD W++  A VVC QL C  +    G      G G I LDDV C G ES LWSC ++GW 
Sbjct: 749  DDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 808

Query: 669  NNDCSHSEDVGVICS----------------------DASDMELRLVGGSSRCAGKVEVN 706
            +++C H ED GVICS                        S + LRLV G  RC G+VEV 
Sbjct: 809  SHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVL 868

Query: 707  VQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASL 766
             +G+ G +C + W  + A VVCRQL CG A        F + +  I++ +  C+G E+ L
Sbjct: 869  YRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYL 928

Query: 767  WDCIRWEWKQTACHLNMEASLICSAHRQ--------------------------PRLVGA 800
            W C    W    C  + +A +ICSA                              RLV  
Sbjct: 929  WSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNG 988

Query: 801  DMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAE 860
               C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+S      FG+G+G    +
Sbjct: 989  GDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1048

Query: 861  KFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD--------------------- 899
              +C G E++L  CP        C HS + GV+CS                         
Sbjct: 1049 DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSES 1108

Query: 900  ---VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
               +RLVNG  +C G+VE+   G WG++CD +WD  DA V+CRQL CG A+S  G    G
Sbjct: 1109 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFG 1168

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
            + S  +      C G+ES L +C      +  C H     VIC+ S +QP  P       
Sbjct: 1169 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT-PSPDTWPT 1227

Query: 1017 PYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQK 1076
             + S     S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++
Sbjct: 1228 SHASTAGSESSL------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1281

Query: 1077 LGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            LGCG A +A  +A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS
Sbjct: 1282 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1341

Query: 1137 ----------------------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITT 1174
                                    ++L L      + C GR+EV Y G+WG+V      T
Sbjct: 1342 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1401

Query: 1175 AIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW------- 1227
              A +VCRQLGCG             GSG + +DD++C      +W C    W       
Sbjct: 1402 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1461

Query: 1228 ----------ERRISSPAEETWITCED---------RIRVRGGDTECSGRVEIWHAGSWG 1268
                       +   +P+ +TW T             +R+  G   C GRVE+ + GSWG
Sbjct: 1462 HEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 1521

Query: 1269 TVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAK 1328
            TVCDD WD  +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC G+ES+LW C   
Sbjct: 1522 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 1581

Query: 1329 PWGQSDCGHKEDAGVRCSGQSLKS 1352
             W   +CGH EDAGV CS    +S
Sbjct: 1582 GWLSHNCGHHEDAGVICSAAQSQS 1605



 Score =  946 bits (2445), Expect = 0.0
 Identities = 525/1303 (40%), Positives = 673/1303 (51%), Gaps = 185/1303 (14%)

Query: 4    PQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTD--LELRLVNGDGPCSGTV 61
            P N W       C H     A V C   L +  L +S  G++  L LRLVNG   C G V
Sbjct: 443  PHNGW---LSHNCQHSE--DAGVICSDTLPTITLPASTVGSESSLALRLVNGGDRCQGRV 497

Query: 62   EVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRFGQAVTRHGKIWLDDVSCY 118
            EV ++G WGTVCDD W+T  + VVC+QLGC ++       RFGQ     G I LDDV C 
Sbjct: 498  EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDVRCS 554

Query: 119  GNESALWECQHREWGSHNCYHGEDVGVNCYG-EANLGLRLVDGNNSCSGRVEVKFQERWG 177
            GNES LW C H  W SHNC H ED GV C G E++L LRLV+G + C GRVEV ++  WG
Sbjct: 555  GNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWG 614

Query: 178  TICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHR 237
            T+CDD W+ N A VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C + 
Sbjct: 615  TVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNN 674

Query: 238  GWGNHDCSHNEDVTLTCY------------------------DSSDLELRLVGGTNRCMG 273
            GW +H+C H+ED  + C                           S L LRLV G++RC G
Sbjct: 675  GWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQG 734

Query: 274  RVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSG 333
            RVE+  +G WGTVC   W+   A+VVC+QLGCG A    G      GS  + LD V CSG
Sbjct: 735  RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 794

Query: 334  NESFLWDCRHSGTVNFDCLHQNDVSVICSDG----------------------ADLELRL 371
            +ES+LW C H+G ++ +C H  D  VICS                        + L LRL
Sbjct: 795  HESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRL 854

Query: 372  ADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDI 431
             +G + C GRVEV     W T+CD +W    A VVC+QLGC ++      A+    +  I
Sbjct: 855  VNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPI 914

Query: 432  WINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS---------------------- 469
             ++ + C+G ES LW C ++G     C    DAGVICS                      
Sbjct: 915  VLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAST 974

Query: 470  --DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFG 527
               ++ L LRLV     C GR+EV YQG WGTVC D W T +A VVC+QLGCG  M   G
Sbjct: 975  VGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPG 1034

Query: 528  MTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDA-------- 579
               F + SGPI LDDV C G+ES +W C H+GW  HNC H ED  V CS           
Sbjct: 1035 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPD 1094

Query: 580  TW--------------GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLD 625
            TW               LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL 
Sbjct: 1095 TWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 1154

Query: 626  CPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS-- 683
            C  ++   G      G G I LDDV C G ES LWSC ++GW +++C H ED GVICS  
Sbjct: 1155 CGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1214

Query: 684  --------------------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNI 723
                                  S + LRLV G  RC G+VEV  +G+ G +C + W  N 
Sbjct: 1215 QSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTND 1274

Query: 724  AEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNM 783
            A VVCRQL CG A        F + +  I++ +  C+G E+ LW C    W    C  + 
Sbjct: 1275 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1334

Query: 784  EASLICSAHR-QP-----------------------RLVGADMPCSGRVEVKHADTWRSV 819
            +A +ICSA + QP                       RLV     C GRVEV +  +W +V
Sbjct: 1335 DAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTV 1394

Query: 820  CDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQH 879
            CD  +  + ANV+CR+L CG A S      FG+G+G    +  +C G E++L  CP    
Sbjct: 1395 CDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 1454

Query: 880  PEDTCIHSREVGVVCSRYTD------------------------VRLVNGKSQCDGQVEI 915
                C H  + GV+CS                            +RLVNG  +C G+VE+
Sbjct: 1455 LSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEV 1514

Query: 916  NVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESL 975
               G WG++CD +WD  DA V+CRQL CG A+S  G    G+ S  +      C G+ES 
Sbjct: 1515 LYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 1574

Query: 976  LDNCQMTVLGAPPCIHGNTVSVICTGSLTQ--PLFPCLANVSDPYLSAVPEGSALICLED 1033
            L +C      +  C H     VIC+ + +Q  P        + P L+   E S       
Sbjct: 1575 LWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSL------ 1628

Query: 1034 KRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGE 1093
              LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+
Sbjct: 1629 -ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ 1687

Query: 1094 GSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            GSGPI LDD+ C+G ES+LW CP +GW  H+C H EDAGVICS
Sbjct: 1688 GSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1730



 Score =  847 bits (2188), Expect = 0.0
 Identities = 484/1273 (38%), Positives = 640/1273 (50%), Gaps = 195/1273 (15%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 719  SSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF 778

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCY------------ 148
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 779  GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 835

Query: 149  ----------GEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC
Sbjct: 836  WPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 895

Query: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY--- 255
              +  + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C    
Sbjct: 896  GWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH 955

Query: 256  ---------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNA 294
                                   S L LRLV G +RC GRVE+  QG WGTVC   W+  
Sbjct: 956  SWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1015

Query: 295  AADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQ 354
             A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++ +C H 
Sbjct: 1016 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 1075

Query: 355  NDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWT 392
             D  VICS                        + L LRL +G + C GRVEV     W T
Sbjct: 1076 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 1135

Query: 393  ICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDG 452
            +CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G
Sbjct: 1136 VCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1195

Query: 453  KAKRTCFRRSDAGVICS----------------------DKADLDLRLVGAHSPCYGRLE 490
                 C    DAGVICS                       ++ L LRLV     C GR+E
Sbjct: 1196 WLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVE 1255

Query: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550
            V Y+G WGTVC D W T +A VVC+QLGCG      G   F + SGPI LDDV C G+ES
Sbjct: 1256 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 1315

Query: 551  NIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW--------------GLRLVGG 588
             +W C H+GW  HNC H ED  V CS           TW               LRLV G
Sbjct: 1316 YLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNG 1375

Query: 589  SNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLD 648
             +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G      G G I LD
Sbjct: 1376 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 1435

Query: 649  DVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA----------------------S 686
            DV C G ES LWSC ++GW +++C H ED GVICS +                      S
Sbjct: 1436 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSES 1495

Query: 687  DMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFT 746
             + LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+       F 
Sbjct: 1496 TLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 1555

Query: 747  ERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP----------- 795
            + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +             
Sbjct: 1556 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 1615

Query: 796  ---------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840
                           RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG 
Sbjct: 1616 NLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 1675

Query: 841  AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY--- 897
            A+S      FG+G+G    +  +C G+E++L  CP        C H  + GV+CS     
Sbjct: 1676 AMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQIN 1735

Query: 898  ---------TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR-QLSCGTAL 947
                     T        S C G +     G + S     + P +A+ +   +++ G  +
Sbjct: 1736 STTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1794

Query: 948  STTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006
            +      +G  ++++  H         + D +   ++L    C   N    I T S  + 
Sbjct: 1795 N------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQIFTSSYNRM 1845

Query: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHDGFWGTICDD 1063
                 +++S      +   ++     D  LRLV+ +S    CAGRVEIYH G WGT+CDD
Sbjct: 1846 TIHFRSDISFQNTGFLAWYNSFP--SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDD 1903

Query: 1064 GWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQH 1123
             W + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQC +RGW  H
Sbjct: 1904 SWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH 1963

Query: 1124 DCRHKEDAGVICS 1136
            +C H+EDAGVICS
Sbjct: 1964 NCNHREDAGVICS 1976



 Score =  545 bits (1403), Expect = e-154
 Identities = 324/875 (37%), Positives = 421/875 (48%), Gaps = 130/875 (14%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 1108 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARF 1167

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 1168 GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1224

Query: 150  -----------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLGC
Sbjct: 1225 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1284

Query: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS- 257
              +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED  + C  S 
Sbjct: 1285 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1344

Query: 258  ---------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAA 296
                                 S L LRLV G +RC GRVE+  +G WGTVC   W+   A
Sbjct: 1345 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1404

Query: 297  DVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQND 356
            +VVC+QLGCG A    G      GS  + LD V CSG+ES+LW C H+G ++ +C H  D
Sbjct: 1405 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1464

Query: 357  VSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWTIC 394
              VICS                        + L LRL +G + C GRVEV     W T+C
Sbjct: 1465 AGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVC 1524

Query: 395  DQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKA 454
            D  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G  
Sbjct: 1525 DDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1584

Query: 455  KRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYGRLE 490
               C    DAGVICS                         ++ L LRLV     C GR+E
Sbjct: 1585 SHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVE 1644

Query: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550
            V Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES
Sbjct: 1645 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNES 1704

Query: 551  NIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLEVYF 600
             +W C H GW  HNC H ED  V C      S    W           S+ C G L  Y 
Sbjct: 1705 YLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYA 1763

Query: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVSCDG 654
             G + +     +    A  V          I +G  N       +  +  + + D S + 
Sbjct: 1764 SGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNS 1823

Query: 655  DE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSSR-- 698
                    +D      S +         D+     G +    S  SD  LRLV  +S   
Sbjct: 1824 SLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYG 1883

Query: 699  -CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNS 757
             CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +  I + + 
Sbjct: 1884 LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDV 1943

Query: 758  GCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
             C+G E++LW C    W    C+   +A +ICS +
Sbjct: 1944 ECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1978



 Score =  172 bits (436), Expect = 2e-42
 Identities = 109/292 (37%), Positives = 142/292 (48%), Gaps = 41/292 (14%)

Query: 1085 ATVSAHFGEGSGPIWLDD-LNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRL 1143
            +T+ +   EGS PI L+  L  T  E  L   PS    +       D+G+      ALRL
Sbjct: 54   STLESTVAEGS-PISLESTLESTVAEGSL--IPSESTLESTVAEGSDSGL------ALRL 104

Query: 1144 YSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSG 1203
             +      C GR+E+ Y G+WG+V   +  T  A +VCRQLGCG             GSG
Sbjct: 105  VNGDGR--CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162

Query: 1204 FMWVDDIQCPKTHISIWQC-----------------------------LSAPWERRISSP 1234
             + +DD++C      +W C                                 W  RIS P
Sbjct: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222

Query: 1235 AEETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA 1294
                       +R+  G   C GRVE+ + GSWGTVCDD WD  +A VVC+QLGCG A++
Sbjct: 223  VPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 282

Query: 1295 ALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            A  +A FGQG+G I LDD+RC G+ES+LW C    W   +CGH EDAGV CS
Sbjct: 283  APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334



 Score =  138 bits (348), Expect = 3e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1944

Query: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1945 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1982



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 1873 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1932

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 1933 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1991

Query: 1017 P 1017
            P
Sbjct: 1992 P 1992



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1885 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1944

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1945 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1975


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 610/1532 (39%), Positives = 783/1532 (51%), Gaps = 224/1532 (14%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQA 103
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     Q 
Sbjct: 230  SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289

Query: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG-------------- 149
                G I LDDV C G+ES LW C H  W +HNC H ED GV C                
Sbjct: 290  GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPT 349

Query: 150  --------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSS 201
                    E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC  +
Sbjct: 350  SHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA 409

Query: 202  FISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY------ 255
              + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C       
Sbjct: 410  TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWS 469

Query: 256  ------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAAD 297
                                S L LRLV G +RC GRVE+  +G WGTVC   W+   A+
Sbjct: 470  TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 529

Query: 298  VVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDV 357
            VVC+QLGCG A+   G      GS  + LD V CSGNES+LW C H+G ++ +C H  D 
Sbjct: 530  VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 589

Query: 358  SVICS-DGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSV 416
             VICS   + L LRL +G + C GRVEV     W T+CD +W    A VVC+QLGC ++ 
Sbjct: 590  GVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 649

Query: 417  FGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS------- 469
                 A+    +  I ++ + C+G+ES LW C  +G     C    DAGVICS       
Sbjct: 650  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 709

Query: 470  -----------------DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAV 512
                              ++ L LRLV     C GR+EV Y+G WGTVC D W T +A V
Sbjct: 710  PRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 769

Query: 513  VCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVI 572
            VC+QLGCG      G   F + SGPI LDDV C G+ES +W C H+GW  HNC H ED  
Sbjct: 770  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAG 829

Query: 573  VTCS--------GDATW--------------GLRLVGGSNRCSGRLEVYFQGRWGTVCDD 610
            V CS           TW               LRLV G +RC GR+EV ++G WGTVCDD
Sbjct: 830  VICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 889

Query: 611  GWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNN 670
             W++  A VVC QL C  +    G      G G I LDDV C G ES LWSC ++GW ++
Sbjct: 890  SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH 949

Query: 671  DCSHSEDVGVICSDA------------------------SDMELRLVGGSSRCAGKVEVN 706
            +C HSED GVICS A                        S + LRLV G  RC G+VEV 
Sbjct: 950  NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 1009

Query: 707  VQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASL 766
             QG+ G +C + W  N A VVCRQL CG A+       F + +  I++ +  C+G E+ L
Sbjct: 1010 YQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYL 1069

Query: 767  WDCIRWEWKQTACHLNMEASLICSAHRQP------------------------RLVGADM 802
            W C    W    C  + +A +ICSA +                          RLV    
Sbjct: 1070 WSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD 1129

Query: 803  PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862
             C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+S      FG+G+G    +  
Sbjct: 1130 RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 1189

Query: 863  QCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD----------------------- 899
            +C G E++L  CP        C H  + GV+CS                           
Sbjct: 1190 RCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1249

Query: 900  -VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGER 958
             +RLVNG  +C G+VE+   G WG++CD +WD  DA V+CRQL CG A S  G    G+ 
Sbjct: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309

Query: 959  SVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPY 1018
            S  +      C G+ES L +C      +  C H     VIC+ S +QP  P        +
Sbjct: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT-PSPDTWPTSH 1368

Query: 1019 LSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLG 1078
             S     S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LG
Sbjct: 1369 ASTAGSESSL------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 1422

Query: 1079 CGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS-- 1136
            CG A +A  +A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS  
Sbjct: 1423 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1482

Query: 1137 --------------------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAI 1176
                                  + L L      + C GR+EV Y G+WG+V      T  
Sbjct: 1483 QSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 1542

Query: 1177 AGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW--------- 1227
            A +VCRQLGCG             GSG + +DD++C      +W C    W         
Sbjct: 1543 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1602

Query: 1228 --------ERRISSPAEETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSW 1267
                     +  S+P  +TW+T          E  + +R   GGD  C GRVE+ + GSW
Sbjct: 1603 DAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSW 1661

Query: 1268 GTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHA 1327
            GTVCDDSWD  +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  
Sbjct: 1662 GTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPH 1721

Query: 1328 KPWGQSDCGHKEDAGVRCSGQSLKSLNASSGH 1359
            K W   +CGH EDAGV CS   + S      H
Sbjct: 1722 KGWLTHNCGHHEDAGVICSATQINSTTTDWWH 1753



 Score = 1098 bits (2841), Expect = 0.0
 Identities = 603/1534 (39%), Positives = 786/1534 (51%), Gaps = 229/1534 (14%)

Query: 38   ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97
            ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 98   ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149
                 FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 152  PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208

Query: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                                E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 209  TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268

Query: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 269  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328

Query: 250  VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
              + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 329  AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388

Query: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 389  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 348  NFDCLHQNDVSVICS------------------------DGADLELRLADGSNNCSGRVE 383
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508

Query: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+GNES
Sbjct: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568

Query: 444  ALWDCTYDGKAKRTCFRRSDAGVICS-DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCH 502
             LW C ++G     C    DAGVICS  ++ L LRLV     C GR+EV Y+G WGTVC 
Sbjct: 569  YLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 628

Query: 503  DRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGK 562
            D W T +A VVC+QLGCG      G   F + SGPI LDDV C G+ES +W C ++GW  
Sbjct: 629  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 688

Query: 563  HNCVHREDVIVTCS------------------------GDATWGLRLVGGSNRCSGRLEV 598
            HNC H ED  V CS                         +++  LRLV GS+RC GR+EV
Sbjct: 689  HNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEV 748

Query: 599  YFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESD 658
             ++G WGTVCDD W++  A VVC QL C  +    G      G G I LDDV C G ES 
Sbjct: 749  LYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESY 808

Query: 659  LWSCRNSGWGNNDCSHSEDVGVICS----------------------DASDMELRLVGGS 696
            LWSC ++GW +++C H ED GVICS                        S + LRLV G 
Sbjct: 809  LWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 868

Query: 697  SRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSN 756
             RC G+VEV  +G+ G +C + W  + A VVCRQL CG A        F + +  I++ +
Sbjct: 869  DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 928

Query: 757  SGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ---------------------- 794
              C+G E+ LW C    W    C  + +A +ICSA                         
Sbjct: 929  VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSE 988

Query: 795  ----PRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHF 850
                 RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+S      F
Sbjct: 989  SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 1048

Query: 851  GKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD----------- 899
            G+G+G    +  +C G E++L  CP        C HS + GV+CS               
Sbjct: 1049 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPT 1108

Query: 900  -------------VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946
                         +RLVNG  +C G+VE+   G WG++CD +WD  DA V+CRQL CG A
Sbjct: 1109 SHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 1168

Query: 947  LSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006
            +S  G    G+ S  +      C G+ES L +C      +  C H     VIC+ S +QP
Sbjct: 1169 MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQP 1228

Query: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWD 1066
              P        + S     S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD
Sbjct: 1229 T-PSPDTWPTSHASTAGSESSL------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD 1281

Query: 1067 LSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCR 1126
             +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C 
Sbjct: 1282 TNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCG 1341

Query: 1127 HKEDAGVICS----------------------EFTALRLYSETETESCAGRLEVFYNGTW 1164
            H EDAGVICS                        ++L L      + C GR+EV Y G+W
Sbjct: 1342 HHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSW 1401

Query: 1165 GSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLS 1224
            G+V      T  A +VCRQLGCG             GSG + +DD++C      +W C  
Sbjct: 1402 GTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPH 1461

Query: 1225 APW-----------------ERRISSPAEETWITCED---------RIRVRGGDTECSGR 1258
              W                  +   +P+ +TW T             +R+  G   C GR
Sbjct: 1462 NGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGR 1521

Query: 1259 VEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGN 1318
            VE+ + GSWGTVCDD WD  +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC G+
Sbjct: 1522 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGH 1581

Query: 1319 ESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            ES+LW C    W   +CGH EDAGV CS    +S
Sbjct: 1582 ESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 1615



 Score =  847 bits (2188), Expect = 0.0
 Identities = 484/1273 (38%), Positives = 640/1273 (50%), Gaps = 195/1273 (15%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 729  SSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF 788

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCY------------ 148
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 789  GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 845

Query: 149  ----------GEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC
Sbjct: 846  WPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 905

Query: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY--- 255
              +  + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C    
Sbjct: 906  GWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH 965

Query: 256  ---------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNA 294
                                   S L LRLV G +RC GRVE+  QG WGTVC   W+  
Sbjct: 966  SWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1025

Query: 295  AADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQ 354
             A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++ +C H 
Sbjct: 1026 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 1085

Query: 355  NDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWT 392
             D  VICS                        + L LRL +G + C GRVEV     W T
Sbjct: 1086 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 1145

Query: 393  ICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDG 452
            +CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G
Sbjct: 1146 VCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1205

Query: 453  KAKRTCFRRSDAGVICS----------------------DKADLDLRLVGAHSPCYGRLE 490
                 C    DAGVICS                       ++ L LRLV     C GR+E
Sbjct: 1206 WLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVE 1265

Query: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550
            V Y+G WGTVC D W T +A VVC+QLGCG      G   F + SGPI LDDV C G+ES
Sbjct: 1266 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 1325

Query: 551  NIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW--------------GLRLVGG 588
             +W C H+GW  HNC H ED  V CS           TW               LRLV G
Sbjct: 1326 YLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNG 1385

Query: 589  SNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLD 648
             +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G      G G I LD
Sbjct: 1386 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 1445

Query: 649  DVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA----------------------S 686
            DV C G ES LWSC ++GW +++C H ED GVICS +                      S
Sbjct: 1446 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSES 1505

Query: 687  DMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFT 746
             + LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+       F 
Sbjct: 1506 TLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 1565

Query: 747  ERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP----------- 795
            + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +             
Sbjct: 1566 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 1625

Query: 796  ---------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840
                           RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG 
Sbjct: 1626 NLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 1685

Query: 841  AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY--- 897
            A+S      FG+G+G    +  +C G+E++L  CP        C H  + GV+CS     
Sbjct: 1686 AMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQIN 1745

Query: 898  ---------TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR-QLSCGTAL 947
                     T        S C G +     G + S     + P +A+ +   +++ G  +
Sbjct: 1746 STTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1804

Query: 948  STTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006
            +      +G  ++++  H         + D +   ++L    C   N    I T S  + 
Sbjct: 1805 N------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQIFTSSYNRM 1855

Query: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHDGFWGTICDD 1063
                 +++S      +   ++     D  LRLV+ +S    CAGRVEIYH G WGT+CDD
Sbjct: 1856 TIHFRSDISFQNTGFLAWYNSFP--SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDD 1913

Query: 1064 GWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQH 1123
             W + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQC +RGW  H
Sbjct: 1914 SWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH 1973

Query: 1124 DCRHKEDAGVICS 1136
            +C H+EDAGVICS
Sbjct: 1974 NCNHREDAGVICS 1986



 Score =  791 bits (2043), Expect = 0.0
 Identities = 445/1155 (38%), Positives = 575/1155 (49%), Gaps = 192/1155 (16%)

Query: 37   LISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFA 96
            +I S   + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +
Sbjct: 591  VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650

Query: 97   M---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG---- 149
                 RFGQ     G I LDDV C G+ES LW C +  W SHNC H ED GV C      
Sbjct: 651  APGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSR 707

Query: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                                E++L LRLV+G++ C GRVEV ++  WGT+CDD W+ N A
Sbjct: 708  STPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDA 767

Query: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED
Sbjct: 768  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 827

Query: 250  VTLTCYDS----------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
              + C  S                      S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 828  AGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 887

Query: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 888  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 947

Query: 348  NFDCLHQNDVSVICSDG------------------------ADLELRLADGSNNCSGRVE 383
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 948  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 1007

Query: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES
Sbjct: 1008 VLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHES 1067

Query: 444  ALWDCTYDGKAKRTCFRRSDAGVICS----------------------DKADLDLRLVGA 481
             LW C ++G     C    DAGVICS                       ++ L LRLV  
Sbjct: 1068 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 1127

Query: 482  HSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLD 541
               C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LD
Sbjct: 1128 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1187

Query: 542  DVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW------------ 581
            DV C G+ES +W C H+GW  HNC H ED  V CS           TW            
Sbjct: 1188 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 1247

Query: 582  --GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAS 639
               LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G     
Sbjct: 1248 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFG 1307

Query: 640  TGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA-------------- 685
             G G I LDDV C G ES LWSC ++GW +++C H ED GVICS +              
Sbjct: 1308 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS 1367

Query: 686  --------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAI 737
                    S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCRQL CG A 
Sbjct: 1368 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAT 1427

Query: 738  RVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHR-QP- 795
                   F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA + QP 
Sbjct: 1428 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1487

Query: 796  ----------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLC 833
                                  RLV     C GRVEV +  +W +VCD  +  + ANV+C
Sbjct: 1488 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 1547

Query: 834  RELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVV 893
            R+L CG A+S      FG+G+G    +  +C G E++L  CP        C H  + GV+
Sbjct: 1548 RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1607

Query: 894  CSRYTD--------------------------VRLVNGKSQCDGQVEINVLGHWGSLCDT 927
            CS                              +RLVNG  +C G+VE+   G WG++CD 
Sbjct: 1608 CSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDD 1667

Query: 928  HWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAP 987
             WD  DA V+CRQL CG A+S  G    G+ S  +      C GNES L +C        
Sbjct: 1668 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTH 1727

Query: 988  PCIHGNTVSVICTGS 1002
             C H     VIC+ +
Sbjct: 1728 NCGHHEDAGVICSAT 1742



 Score =  545 bits (1403), Expect = e-154
 Identities = 324/875 (37%), Positives = 421/875 (48%), Gaps = 130/875 (14%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 1118 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARF 1177

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 1178 GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1234

Query: 150  -----------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLGC
Sbjct: 1235 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294

Query: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS- 257
              +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED  + C  S 
Sbjct: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354

Query: 258  ---------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAA 296
                                 S L LRLV G +RC GRVE+  +G WGTVC   W+   A
Sbjct: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414

Query: 297  DVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQND 356
            +VVC+QLGCG A    G      GS  + LD V CSG+ES+LW C H+G ++ +C H  D
Sbjct: 1415 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1474

Query: 357  VSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWTIC 394
              VICS                        + L LRL +G + C GRVEV     W T+C
Sbjct: 1475 AGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVC 1534

Query: 395  DQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKA 454
            D  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G  
Sbjct: 1535 DDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1594

Query: 455  KRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYGRLE 490
               C    DAGVICS                         ++ L LRLV     C GR+E
Sbjct: 1595 SHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVE 1654

Query: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550
            V Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES
Sbjct: 1655 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNES 1714

Query: 551  NIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLEVYF 600
             +W C H GW  HNC H ED  V C      S    W           S+ C G L  Y 
Sbjct: 1715 YLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYA 1773

Query: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVSCDG 654
             G + +     +    A  V          I +G  N       +  +  + + D S + 
Sbjct: 1774 SGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNS 1833

Query: 655  DE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSSR-- 698
                    +D      S +         D+     G +    S  SD  LRLV  +S   
Sbjct: 1834 SLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYG 1893

Query: 699  -CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNS 757
             CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +  I + + 
Sbjct: 1894 LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDV 1953

Query: 758  GCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
             C+G E++LW C    W    C+   +A +ICS +
Sbjct: 1954 ECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988



 Score =  172 bits (436), Expect = 2e-42
 Identities = 109/292 (37%), Positives = 142/292 (48%), Gaps = 41/292 (14%)

Query: 1085 ATVSAHFGEGSGPIWLDD-LNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRL 1143
            +T+ +   EGS PI L+  L  T  E  L   PS    +       D+G+      ALRL
Sbjct: 54   STLESTVAEGS-PISLESTLESTVAEGSL--IPSESTLESTVAEGSDSGL------ALRL 104

Query: 1144 YSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSG 1203
             +      C GR+E+ Y G+WG+V   +  T  A +VCRQLGCG             GSG
Sbjct: 105  VNGDGR--CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162

Query: 1204 FMWVDDIQCPKTHISIWQC-----------------------------LSAPWERRISSP 1234
             + +DD++C      +W C                                 W  RIS P
Sbjct: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222

Query: 1235 AEETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA 1294
                       +R+  G   C GRVE+ + GSWGTVCDD WD  +A VVC+QLGCG A++
Sbjct: 223  VPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 282

Query: 1295 ALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            A  +A FGQG+G I LDD+RC G+ES+LW C    W   +CGH EDAGV CS
Sbjct: 283  APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334



 Score =  138 bits (348), Expect = 3e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954

Query: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 1943 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 2001

Query: 1017 P 1017
            P
Sbjct: 2002 P 2002



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score =  856 bits (2212), Expect = 0.0
 Identities = 485/1285 (37%), Positives = 647/1285 (50%), Gaps = 201/1285 (15%)

Query: 38   ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97
            ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 98   ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149
                 FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 152  PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208

Query: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                                E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 209  TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268

Query: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 269  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328

Query: 250  VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
              + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 329  AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388

Query: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 389  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 348  NFDCLHQNDVSVICS------------------------DGADLELRLADGSNNCSGRVE 383
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508

Query: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+GNES
Sbjct: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568

Query: 444  ALWDCTYDGKAKRTCFRRSDAGVICS-------------------------DKADLDLRL 478
             LW C ++G     C    DAGVICS                          ++ L LRL
Sbjct: 569  YLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRL 628

Query: 479  VGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPI 538
            V     C GR+EV Y+G WGTVC D W T +A VVC+QLGCG      G   F + SGPI
Sbjct: 629  VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPI 688

Query: 539  WLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS---------------------- 576
             LDDV C G+ES +W C ++GW  HNC H ED  V CS                      
Sbjct: 689  VLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAG 748

Query: 577  GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLG 636
             +++  LRLV G +RC GR+EV +QG WGTVCDD W++  A VVC QL C  ++   G  
Sbjct: 749  SESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 808

Query: 637  NASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS------------- 683
                G G I LDDV C G ES LWSC ++GW +++C HSED GVICS             
Sbjct: 809  RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTW 868

Query: 684  ---------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECG 734
                       S + LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG
Sbjct: 869  PTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCG 928

Query: 735  SAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ 794
             A+       F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA + 
Sbjct: 929  WAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQS 988

Query: 795  P--------------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHA 828
                                       RLV     C GRVEV +  +W +VCD  +  + 
Sbjct: 989  QSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTND 1048

Query: 829  ANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSR 888
            ANV+CR+L CG A+S      FG+G+G    +  +C G+E++L  CP        C H  
Sbjct: 1049 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHE 1108

Query: 889  EVGVVCS------------RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARV 936
            + GV+CS              T        S C G +     G + S     + P +A+ 
Sbjct: 1109 DAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKC 1167

Query: 937  LCR-QLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNT 994
            +   +++ G  ++      +G  ++++  H         + D +   ++L    C   N 
Sbjct: 1168 VWEIEVNSGYRIN------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---ND 1218

Query: 995  VSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEI 1051
               I T S  +      +++S      +   ++     D  LRLV+ +S    CAGRVEI
Sbjct: 1219 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF--PSDATLRLVNLNSSYGLCAGRVEI 1276

Query: 1052 YHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESH 1111
            YH G WGT+CDD W + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES 
Sbjct: 1277 YHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTEST 1336

Query: 1112 LWQCPSRGWGQHDCRHKEDAGVICS 1136
            LWQC +RGW  H+C H+EDAGVICS
Sbjct: 1337 LWQCRNRGWFSHNCNHREDAGVICS 1361



 Score =  715 bits (1845), Expect = 0.0
 Identities = 402/1039 (38%), Positives = 522/1039 (50%), Gaps = 163/1039 (15%)

Query: 474  LDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKE 533
            L LRLV     C GR+E+ Y+G WGTVC D W T +A VVC+QLGCG  M   G  +F +
Sbjct: 100  LALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ 159

Query: 534  ASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG---------------- 577
             SGPI LDDV C G+ES +W C H+GW  HNC H ED  V CS                 
Sbjct: 160  GSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRI 219

Query: 578  ---------DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPS 628
                     +++  LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C  
Sbjct: 220  SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279

Query: 629  SIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS----- 683
            ++   G      G G I LDDV C G ES LWSC ++GW  ++C HSED GVICS     
Sbjct: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339

Query: 684  -----------------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEV 726
                               S + LRLV G  RC G+VEV  +G+ G +C + W  + A V
Sbjct: 340  PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399

Query: 727  VCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEAS 786
            VCRQL CG A        F + +  I++ +  C+G E+ LW C    W    C  + +A 
Sbjct: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459

Query: 787  LICSAHRQ--------------------------PRLVGADMPCSGRVEVKHADTWRSVC 820
            +ICSA                              RLV     C GRVEV +  +W +VC
Sbjct: 460  VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 519

Query: 821  DSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHP 880
            D  +  + ANV+CR+L CG A+       FG+G+G    +  +C G+E++L  CP     
Sbjct: 520  DDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWL 579

Query: 881  EDTCIHSREVGVVCSRYT---------------------------DVRLVNGKSQCDGQV 913
               C HS + GV+CS                               +RLVNG  +C G+V
Sbjct: 580  SHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRV 639

Query: 914  EINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNE 973
            E+   G WG++CD  WD  DA V+CRQL CG A S  G    G+ S  +      C G+E
Sbjct: 640  EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 699

Query: 974  SLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLED 1033
            S L +C      +  C H     VIC+ + ++         S P     P   A     +
Sbjct: 700  SYLWSCPNNGWLSHNCGHHEDAGVICSAAQSR---------STPRPDTWPTSHASTAGSE 750

Query: 1034 KRL--RLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHF 1091
              L  RLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +A F
Sbjct: 751  SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 810

Query: 1092 GEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS--------------- 1136
            G+GSGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS               
Sbjct: 811  GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPT 870

Query: 1137 -------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGEN 1189
                     + L L      + C GR+EV Y G+WG+V      T  A +VCRQLGCG  
Sbjct: 871  SRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930

Query: 1190 GVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ERRIS 1232
                       GSG + +DD++C      +W C    W                  +  S
Sbjct: 931  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 990

Query: 1233 SPAEETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDLAEA 1280
            +P  +TW+T          E  + +R   GGD  C GRVE+ + GSWGTVCDDSWD  +A
Sbjct: 991  TPRPDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDTNDA 1049

Query: 1281 EVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKED 1340
             VVC+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  K W   +CGH ED
Sbjct: 1050 NVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED 1109

Query: 1341 AGVRCSGQSLKSLNASSGH 1359
            AGV CS   + S      H
Sbjct: 1110 AGVICSATQINSTTTDWWH 1128



 Score =  548 bits (1411), Expect = e-155
 Identities = 324/878 (36%), Positives = 420/878 (47%), Gaps = 133/878 (15%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++       RF
Sbjct: 490  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 549

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
            GQ     G I LDDV C GNES LW C H  W SHNC H ED GV C             
Sbjct: 550  GQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPR 606

Query: 150  --------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQ 195
                          E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQ
Sbjct: 607  SWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 666

Query: 196  LGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY 255
            LGC  +  + G         PI LDD+ C G+E  LW+C + GW +H+C H+ED  + C 
Sbjct: 667  LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 726

Query: 256  ----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNN 293
                                    S L LRLV G +RC GRVE+  QG WGTVC   W+ 
Sbjct: 727  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 786

Query: 294  AAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLH 353
              A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++ +C H
Sbjct: 787  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 846

Query: 354  QNDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWW 391
              D  VICS                        + L LRL +G + C GRVEV     W 
Sbjct: 847  SEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWG 906

Query: 392  TICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYD 451
            T+CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++
Sbjct: 907  TVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHN 966

Query: 452  GKAKRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYG 487
            G     C    DAGVICS                         ++ L LRLV     C G
Sbjct: 967  GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1026

Query: 488  RLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIG 547
            R+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C G
Sbjct: 1027 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1086

Query: 548  NESNIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLE 597
            NES +W C H GW  HNC H ED  V C      S    W           S+ C G L 
Sbjct: 1087 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL- 1145

Query: 598  VYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVS 651
             Y  G + +     +    A  V          I +G  N       +  +  + + D S
Sbjct: 1146 FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGS 1205

Query: 652  CDGDE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSS 697
             +         +D      S +         D+     G +    S  SD  LRLV  +S
Sbjct: 1206 LNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNS 1265

Query: 698  R---CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILM 754
                CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +  I +
Sbjct: 1266 SYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITL 1325

Query: 755  SNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
             +  C+G E++LW C    W    C+   +A +ICS +
Sbjct: 1326 DDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1363



 Score =  499 bits (1286), Expect = e-141
 Identities = 288/766 (37%), Positives = 381/766 (49%), Gaps = 113/766 (14%)

Query: 686  SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHF 745
            S + LRLV G  RC G+VE+  +G+ G +C + W  N A VVCRQL CG A+       F
Sbjct: 98   SGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF 157

Query: 746  TERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP---------- 795
             + +  I + +  C+G E+ LW C    W    C    +A +ICSA  QP          
Sbjct: 158  GQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSA-AQPQSTLRPESWP 216

Query: 796  ------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELN 837
                              RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L 
Sbjct: 217  VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276

Query: 838  CGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY 897
            CG A+S      FG+G+G    +  +C G E++L  CP        C HS + GV+CS  
Sbjct: 277  CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336

Query: 898  TD------------------------VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPED 933
                                      +RLVNG  +C G+VE+   G WG++CD  WD  D
Sbjct: 337  QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396

Query: 934  ARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGN 993
            A V+CRQL CG A S  G    G+ S  +      C G ES L +C      +  C H  
Sbjct: 397  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456

Query: 994  TVSVICTG--SLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEI 1051
               VIC+   S + P    L  ++ P  +   E S         LRLV+G  RC GRVE+
Sbjct: 457  DAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLA-------LRLVNGGDRCQGRVEV 509

Query: 1052 YHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESH 1111
             + G WGT+CDD WD +DA+VVC++LGCG A  A  +A FG+GSGPI LDD+ C+G ES+
Sbjct: 510  LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESY 569

Query: 1112 LWQCPSRGWGQHDCRHKEDAGVICSEF-------------------------TALRLYSE 1146
            LW CP  GW  H+C H EDAGVICS                           ++L L   
Sbjct: 570  LWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLV 629

Query: 1147 TETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMW 1206
               + C GR+EV Y G+WG+V   +  T  A +VCRQLGCG             GSG + 
Sbjct: 630  NGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV 689

Query: 1207 VDDIQCPKTHISIWQCLSAPW-----------------ERRISSPAEETWITCED----- 1244
            +DD++C      +W C +  W                  +  S+P  +TW T        
Sbjct: 690  LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGS 749

Query: 1245 ----RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDAS 1300
                 +R+  G   C GRVE+ + GSWGTVCDDSWD  +A VVC+QLGCG A++A  +A 
Sbjct: 750  ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 809

Query: 1301 FGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            FGQG+G I LDD+RC G+ES+LW C    W   +CGH EDAGV CS
Sbjct: 810  FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 855



 Score =  307 bits (787), Expect = 4e-83
 Identities = 175/415 (42%), Positives = 221/415 (53%), Gaps = 67/415 (16%)

Query: 985  GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044
            G+P  +     S +  GSL     P  + +     S V EGS         LRLV+GD R
Sbjct: 63   GSPISLESTLESTVAEGSL----IPSESTLE----STVAEGSD----SGLALRLVNGDGR 110

Query: 1045 CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLN 1104
            C GRVEI + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ 
Sbjct: 111  CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVR 170

Query: 1105 CTGMESHLWQCPSRGWGQHDCRHKEDAGVICS----------EFTALRLYSETETES--- 1151
            C+G ES+LW CP  GW  H+C H EDAGVICS          E   +R+     TE    
Sbjct: 171  CSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSES 230

Query: 1152 ------------CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSK 1199
                        C GR+EV Y G+WG+V      T  A +VCRQLGCG            
Sbjct: 231  SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 290

Query: 1200 TGSGFMWVDDIQCPKTHISIWQC-------------------LSAPWERRISSPAEETWI 1240
             GSG + +DD++C      +W C                    SAP  R   +P+ +TW 
Sbjct: 291  QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR--PTPSPDTWP 348

Query: 1241 TCED---------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291
            T             +R+  G   C GRVE+ + GSWGTVCDDSWD ++A VVC+QLGCG 
Sbjct: 349  TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGW 408

Query: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            A +A  +A FGQG+G I LDD+RC G ES+LW C    W   +C H EDAGV CS
Sbjct: 409  ATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463



 Score =  138 bits (348), Expect = 3e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329

Query: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1367



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 1258 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1317

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 1318 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1376

Query: 1017 P 1017
            P
Sbjct: 1377 P 1377



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1270 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1329

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1330 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1360


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score =  855 bits (2208), Expect = 0.0
 Identities = 486/1282 (37%), Positives = 645/1282 (50%), Gaps = 198/1282 (15%)

Query: 38   ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97
            ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 98   ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCY------ 148
                 FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 152  PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208

Query: 149  -------------------GEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                                E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 209  TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268

Query: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 269  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328

Query: 250  VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
              + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 329  AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388

Query: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 389  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 348  NFDCLHQNDVSVICS------------------------DGADLELRLADGSNNCSGRVE 383
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508

Query: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES
Sbjct: 509  VLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHES 568

Query: 444  ALWDCTYDGKAKRTCFRRSDAGVICS----------------------DKADLDLRLVGA 481
             LW C ++G     C    DAGVICS                       ++ L LRLV  
Sbjct: 569  YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 628

Query: 482  HSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLD 541
               C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LD
Sbjct: 629  GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 688

Query: 542  DVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW------------ 581
            DV C G+ES +W C H+GW  HNC H ED  V CS           TW            
Sbjct: 689  DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 748

Query: 582  --GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAS 639
               LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G     
Sbjct: 749  SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFG 808

Query: 640  TGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS---------------- 683
             G G I LDDV C G ES LWSC ++GW +++C H ED GVICS                
Sbjct: 809  QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS 868

Query: 684  ------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAI 737
                    S + LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+
Sbjct: 869  RASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAM 928

Query: 738  RVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP-- 795
                   F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +    
Sbjct: 929  SAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQST 988

Query: 796  ------------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANV 831
                                    RLV     C GRVEV +  +W +VCD  +  + ANV
Sbjct: 989  PRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANV 1048

Query: 832  LCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVG 891
            +CR+L CG A+S      FG+G+G    +  +C G+E++L  CP        C H  + G
Sbjct: 1049 VCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAG 1108

Query: 892  VVCS------------RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR 939
            V+CS              T        S C G +     G + S     + P +A+ +  
Sbjct: 1109 VICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWE 1167

Query: 940  -QLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSV 997
             +++ G  ++      +G  ++++  H         + D +   ++L    C   N    
Sbjct: 1168 IEVNSGYRIN------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQ 1218

Query: 998  ICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHD 1054
            I T S  +      +++S      +   ++     D  LRLV+ +S    CAGRVEIYH 
Sbjct: 1219 IFTSSYNRMTIHFRSDISFQNTGFLAWYNSF--PSDATLRLVNLNSSYGLCAGRVEIYHG 1276

Query: 1055 GFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQ 1114
            G WGT+CDD W + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQ
Sbjct: 1277 GTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ 1336

Query: 1115 CPSRGWGQHDCRHKEDAGVICS 1136
            C +RGW  H+C H+EDAGVICS
Sbjct: 1337 CRNRGWFSHNCNHREDAGVICS 1358



 Score =  723 bits (1866), Expect = 0.0
 Identities = 406/1034 (39%), Positives = 526/1034 (50%), Gaps = 156/1034 (15%)

Query: 474  LDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKE 533
            L LRLV     C GR+E+ Y+G WGTVC D W T +A VVC+QLGCG  M   G  +F +
Sbjct: 100  LALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ 159

Query: 534  ASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG---------------- 577
             SGPI LDDV C G+ES +W C H+GW  HNC H ED  V CS                 
Sbjct: 160  GSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRI 219

Query: 578  ---------DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPS 628
                     +++  LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C  
Sbjct: 220  SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279

Query: 629  SIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS----- 683
            ++   G      G G I LDDV C G ES LWSC ++GW  ++C HSED GVICS     
Sbjct: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339

Query: 684  -----------------DASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEV 726
                               S + LRLV G  RC G+VEV  +G+ G +C + W  + A V
Sbjct: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399

Query: 727  VCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEAS 786
            VCRQL CG A        F + +  I++ +  C+G E+ LW C    W    C  + +A 
Sbjct: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459

Query: 787  LICSAHRQ--------------------------PRLVGADMPCSGRVEVKHADTWRSVC 820
            +ICSA                              RLV     C GRVEV +  +W +VC
Sbjct: 460  VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVC 519

Query: 821  DSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHP 880
            D  +  + ANV+CR+L CG A+S      FG+G+G    +  +C G E++L  CP     
Sbjct: 520  DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 579

Query: 881  EDTCIHSREVGVVCSRYTD------------------------VRLVNGKSQCDGQVEIN 916
               C HS + GV+CS                            +RLVNG  +C G+VE+ 
Sbjct: 580  SHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVL 639

Query: 917  VLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLL 976
              G WG++CD +WD  DA V+CRQL CG A+S  G    G+ S  +      C G+ES L
Sbjct: 640  YRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYL 699

Query: 977  DNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRL 1036
             +C      +  C H     VIC+ S +QP  P        + S     S+L       L
Sbjct: 700  WSCPHNGWLSHNCGHHEDAGVICSASQSQPT-PSPDTWPTSHASTAGSESSLA------L 752

Query: 1037 RLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSG 1096
            RLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+GSG
Sbjct: 753  RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 812

Query: 1097 PIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEF------------------ 1138
            PI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS                    
Sbjct: 813  PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 872

Query: 1139 ----TALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSL 1194
                + L L      + C GR+EV Y G+WG+V      T  A +VCRQLGCG       
Sbjct: 873  AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 932

Query: 1195 APLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ERRISSPAEE 1237
                  GSG + +DD++C      +W C    W                  +  S+P  +
Sbjct: 933  NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 992

Query: 1238 TWITC---------EDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQ 1285
            TW+T          E  + +R   GGD  C GRVE+ + GSWGTVCDDSWD  +A VVC+
Sbjct: 993  TWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDTNDANVVCR 1051

Query: 1286 QLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRC 1345
            QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  K W   +CGH EDAGV C
Sbjct: 1052 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1111

Query: 1346 SGQSLKSLNASSGH 1359
            S   + S      H
Sbjct: 1112 SATQINSTTTDWWH 1125



 Score =  549 bits (1414), Expect = e-156
 Identities = 325/875 (37%), Positives = 421/875 (48%), Gaps = 130/875 (14%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV +QG WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 490  SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 549

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 550  GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 606

Query: 150  -----------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLGC
Sbjct: 607  WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 666

Query: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS- 257
              +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED  + C  S 
Sbjct: 667  GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 726

Query: 258  ---------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAA 296
                                 S L LRLV G +RC GRVE+  +G WGTVC   W+   A
Sbjct: 727  SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 786

Query: 297  DVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQND 356
            +VVC+QLGCG A    G      GS  + LD V CSG+ES+LW C H+G ++ +C H  D
Sbjct: 787  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 846

Query: 357  VSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWTIC 394
              VICS                        + L LRL +G + C GRVEV     W T+C
Sbjct: 847  AGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVC 906

Query: 395  DQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKA 454
            D  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G  
Sbjct: 907  DDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 966

Query: 455  KRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYGRLE 490
               C    DAGVICS                         ++ L LRLV     C GR+E
Sbjct: 967  SHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVE 1026

Query: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550
            V Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES
Sbjct: 1027 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNES 1086

Query: 551  NIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLEVYF 600
             +W C H GW  HNC H ED  V C      S    W           S+ C G L  Y 
Sbjct: 1087 YLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYA 1145

Query: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVSCDG 654
             G + +     +    A  V          I +G  N       +  +  + + D S + 
Sbjct: 1146 SGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNS 1205

Query: 655  DE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSSR-- 698
                    +D      S +         D+     G +    S  SD  LRLV  +S   
Sbjct: 1206 SLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYG 1265

Query: 699  -CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNS 757
             CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +  I + + 
Sbjct: 1266 LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDV 1325

Query: 758  GCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
             C+G E++LW C    W    C+   +A +ICS +
Sbjct: 1326 ECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1360



 Score =  307 bits (787), Expect = 4e-83
 Identities = 175/415 (42%), Positives = 221/415 (53%), Gaps = 67/415 (16%)

Query: 985  GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044
            G+P  +     S +  GSL     P  + +     S V EGS         LRLV+GD R
Sbjct: 63   GSPISLESTLESTVAEGSL----IPSESTLE----STVAEGSD----SGLALRLVNGDGR 110

Query: 1045 CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLN 1104
            C GRVEI + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ 
Sbjct: 111  CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVR 170

Query: 1105 CTGMESHLWQCPSRGWGQHDCRHKEDAGVICS----------EFTALRLYSETETES--- 1151
            C+G ES+LW CP  GW  H+C H EDAGVICS          E   +R+     TE    
Sbjct: 171  CSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSES 230

Query: 1152 ------------CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSK 1199
                        C GR+EV Y G+WG+V      T  A +VCRQLGCG            
Sbjct: 231  SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 290

Query: 1200 TGSGFMWVDDIQCPKTHISIWQC-------------------LSAPWERRISSPAEETWI 1240
             GSG + +DD++C      +W C                    SAP  R   +P+ +TW 
Sbjct: 291  QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR--PTPSPDTWP 348

Query: 1241 TCED---------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291
            T             +R+  G   C GRVE+ + GSWGTVCDDSWD ++A VVC+QLGCG 
Sbjct: 349  TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGW 408

Query: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            A +A  +A FGQG+G I LDD+RC G ES+LW C    W   +C H EDAGV CS
Sbjct: 409  ATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463



 Score =  138 bits (348), Expect = 3e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1326

Query: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1327 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1364



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 1255 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1314

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 1315 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1373

Query: 1017 P 1017
            P
Sbjct: 1374 P 1374



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1267 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1326

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1327 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1357


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score =  747 bits (1929), Expect = 0.0
 Identities = 430/1151 (37%), Positives = 573/1151 (49%), Gaps = 176/1151 (15%)

Query: 150  EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVN 209
            ++ L LRLV+G+  C GRVE+ ++  WGT+CDD W+ N A VVCRQLGC  +  + G   
Sbjct: 97   DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAW 156

Query: 210  SPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY-------------- 255
                  PI LDD+ C G+E  LW+C H GW +H+C H ED  + C               
Sbjct: 157  FGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWP 216

Query: 256  -----------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLG 304
                         S L LRLV G +RC GRVE+  +G WGTVC   W+   A+VVC+QLG
Sbjct: 217  VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276

Query: 305  CGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS-- 362
            CG A+   G      GS  + LD V CSG+ES+LW C H+G +  +C H  D  VICS  
Sbjct: 277  CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336

Query: 363  --------------------DGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQ 402
                                  + L LRL +G + C GRVEV     W T+CD +W    
Sbjct: 337  QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396

Query: 403  ALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRS 462
            A VVC+QLGC ++      A+    +  I ++ + C+G ES LW C ++G     C    
Sbjct: 397  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456

Query: 463  DAGVICS-------------DKAD-----------------LDLRLVGAHSPCYGRLEVK 492
            DAGVICS             D+ D                 L LRLV     C GR+EV 
Sbjct: 457  DAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 516

Query: 493  YQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNI 552
            Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES +
Sbjct: 517  YRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYL 576

Query: 553  WDCEHSGWGKHNCVHREDVIVTCSGDA--------TW--------------GLRLVGGSN 590
            W C H+GW  HNC H ED  V CS           TW               LRLV G +
Sbjct: 577  WSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGD 636

Query: 591  RCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDV 650
            RC GR+EV +QG WGTVCDD W++  A VVC QL C  ++   G      G G I LDDV
Sbjct: 637  RCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 696

Query: 651  SCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA----------------------SDM 688
             C G ES LWSC ++GW +++C HSED GVICS +                      S +
Sbjct: 697  RCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTL 756

Query: 689  ELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTER 748
             LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+       F + 
Sbjct: 757  ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 816

Query: 749  TLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP------------- 795
            +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +               
Sbjct: 817  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 876

Query: 796  -------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842
                         RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+
Sbjct: 877  PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 936

Query: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY----- 897
            S      FG+G+G    +  +C G+E++L  CP        C H  + GV+CS       
Sbjct: 937  SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 996

Query: 898  -------TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR-QLSCGTALST 949
                   T        S C G +     G + S     + P +A+ +   +++ G  ++ 
Sbjct: 997  TTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRIN- 1054

Query: 950  TGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSVICTGSLTQPLF 1008
                 +G  ++++  H         + D +   ++L    C   N    I T S  +   
Sbjct: 1055 -----LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQIFTSSYNRMTI 1106

Query: 1009 PCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHDGFWGTICDDGW 1065
               +++S      +   ++     D  LRLV+ +S    CAGRVEIYH G WGT+CDD W
Sbjct: 1107 HFRSDISFQNTGFLAWYNSFP--SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW 1164

Query: 1066 DLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDC 1125
             + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQC +RGW  H+C
Sbjct: 1165 TIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNC 1224

Query: 1126 RHKEDAGVICS 1136
             H+EDAGVICS
Sbjct: 1225 NHREDAGVICS 1235



 Score =  680 bits (1755), Expect = 0.0
 Identities = 364/902 (40%), Positives = 464/902 (51%), Gaps = 151/902 (16%)

Query: 38  ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97
           ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 92  VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 98  ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149
                FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 152 PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208

Query: 150 --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189
                               E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 209 TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268

Query: 190 AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249
            VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 269 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328

Query: 250 VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
             + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388

Query: 288 HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
              W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448

Query: 348 NFDCLHQNDVSVICSDG------------------------------ADLELRLADGSNN 377
           + +C H  D  VICS                                + L LRL +G + 
Sbjct: 449 SHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR 508

Query: 378 CSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSIS 437
           C GRVEV     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + 
Sbjct: 509 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVR 568

Query: 438 CTGNESALWDCTYDGKAKRTCFRRSDAGVICS----------------------DKADLD 475
           C+GNES LW C ++G     C    DAGVICS                       ++ L 
Sbjct: 569 CSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLA 628

Query: 476 LRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEAS 535
           LRLV     C GR+EV YQG WGTVC D W T +A VVC+QLGCG  M   G   F + S
Sbjct: 629 LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 688

Query: 536 GPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS------------------- 576
           GPI LDDV C G+ES +W C H+GW  HNC H ED  V CS                   
Sbjct: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRAS 748

Query: 577 ---GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGM 633
               ++T  LRLV G +RC GR+EV +QG WGTVCDD W++  A VVC QL C  ++   
Sbjct: 749 TAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 808

Query: 634 GLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA-------- 685
           G      G G I LDDV C G ES LWSC ++GW +++C H ED GVICS A        
Sbjct: 809 GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 868

Query: 686 ----------------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCR 729
                           S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCR
Sbjct: 869 DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCR 928

Query: 730 QLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLIC 789
           QL CG A+       F + +  I++ +  C+G E+ LW C    W    C  + +A +IC
Sbjct: 929 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 988

Query: 790 SA 791
           SA
Sbjct: 989 SA 990



 Score =  606 bits (1563), Expect = e-173
 Identities = 349/916 (38%), Positives = 456/916 (49%), Gaps = 144/916 (15%)

Query: 578  DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGN 637
            D+   LRLV G  RC GR+E+ ++G WGTVCDD W++  A VVC QL C  ++   G   
Sbjct: 97   DSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAW 156

Query: 638  ASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA------------ 685
               G G I LDDV C G ES LWSC ++GW +++C H ED GVICS A            
Sbjct: 157  FGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWP 216

Query: 686  -------------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLE 732
                         S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCRQL 
Sbjct: 217  VRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276

Query: 733  CGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
            CG A+       F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA 
Sbjct: 277  CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336

Query: 793  RQP------------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHA 828
            +                          RLV     C GRVEV +  +W +VCD  +    
Sbjct: 337  QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSD 396

Query: 829  ANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSR 888
            ANV+CR+L CG A S      FG+G+G    +  +C G E++L  CP        C HS 
Sbjct: 397  ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSE 456

Query: 889  EVGVVCSRY-------------TD-------------------VRLVNGKSQCDGQVEIN 916
            + GV+CS               TD                   +RLVNG  +C G+VE+ 
Sbjct: 457  DAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 516

Query: 917  VLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLL 976
              G WG++CD  WD  DA V+CRQL CG A+   G    G+ S  +      C GNES L
Sbjct: 517  YRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYL 576

Query: 977  DNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRL 1036
             +C      +  C H     VIC+ + ++         S P     P   A     +  L
Sbjct: 577  WSCPHNGWLSHNCGHSEDAGVICSAAQSR---------STPRPDTWPTSHASTAGSESSL 627

Query: 1037 --RLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEG 1094
              RLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+G
Sbjct: 628  ALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 687

Query: 1095 SGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS------------------ 1136
            SGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS                  
Sbjct: 688  SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRA 747

Query: 1137 ----EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVV 1192
                  + L L      + C GR+EV Y G+WG+V      T  A +VCRQLGCG     
Sbjct: 748  STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 807

Query: 1193 SLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW-----------------ERRISSPA 1235
                    GSG + +DD++C      +W C    W                  +  S+P 
Sbjct: 808  PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 867

Query: 1236 EETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVV 1283
             +TW+T          E  + +R   GGD  C GRVE+ + GSWGTVCDDSWD  +A VV
Sbjct: 868  PDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSWGTVCDDSWDTNDANVV 926

Query: 1284 CQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGV 1343
            C+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  K W   +CGH EDAGV
Sbjct: 927  CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 986

Query: 1344 RCSGQSLKSLNASSGH 1359
             CS   + S      H
Sbjct: 987  ICSATQINSTTTDWWH 1002



 Score =  551 bits (1419), Expect = e-156
 Identities = 325/883 (36%), Positives = 422/883 (47%), Gaps = 138/883 (15%)

Query: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100
            + L LRLVNG   C G VEV ++G WGTVCDD W+T+ + VVC+QLGC ++ +     RF
Sbjct: 359  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 418

Query: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
            GQ     G I LDDV C G ES LW C H  W SHNC H ED GV C             
Sbjct: 419  GQG---SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGE 475

Query: 150  -------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAA 190
                               E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A 
Sbjct: 476  RDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 535

Query: 191  VVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV 250
            VVCRQLGC  + ++ G         PI LDD+ C GNE  LW+C H GW +H+C H+ED 
Sbjct: 536  VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 595

Query: 251  TLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCH 288
             + C                         S L LRLV G +RC GRVE+  QG WGTVC 
Sbjct: 596  GVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCD 655

Query: 289  HKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVN 348
              W+   A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++
Sbjct: 656  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 715

Query: 349  FDCLHQNDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRI 386
             +C H  D  VICS                        + L LRL +G + C GRVEV  
Sbjct: 716  HNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 775

Query: 387  HEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALW 446
               W T+CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW
Sbjct: 776  QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 835

Query: 447  DCTYDGKAKRTCFRRSDAGVICS------------------------DKADLDLRLVGAH 482
             C ++G     C    DAGVICS                         ++ L LRLV   
Sbjct: 836  SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 895

Query: 483  SPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDD 542
              C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDD
Sbjct: 896  DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 955

Query: 543  VSCIGNESNIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRC 592
            V C GNES +W C H GW  HNC H ED  V C      S    W           S+ C
Sbjct: 956  VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNC 1015

Query: 593  SGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIW 646
             G L  Y  G + +     +    A  V          I +G  N       +  +  + 
Sbjct: 1016 GGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1074

Query: 647  LDDVSCDGDE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRL 692
            + D S +         +D      S +         D+     G +    S  SD  LRL
Sbjct: 1075 IFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRL 1134

Query: 693  VGGSSR---CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERT 749
            V  +S    CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +
Sbjct: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1194

Query: 750  LHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
              I + +  C+G E++LW C    W    C+   +A +ICS +
Sbjct: 1195 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1237



 Score =  307 bits (787), Expect = 4e-83
 Identities = 175/415 (42%), Positives = 221/415 (53%), Gaps = 67/415 (16%)

Query: 985  GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044
            G+P  +     S +  GSL     P  + +     S V EGS         LRLV+GD R
Sbjct: 63   GSPISLESTLESTVAEGSL----IPSESTLE----STVAEGSD----SGLALRLVNGDGR 110

Query: 1045 CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLN 1104
            C GRVEI + G WGT+CDD WD +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ 
Sbjct: 111  CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVR 170

Query: 1105 CTGMESHLWQCPSRGWGQHDCRHKEDAGVICS----------EFTALRLYSETETES--- 1151
            C+G ES+LW CP  GW  H+C H EDAGVICS          E   +R+     TE    
Sbjct: 171  CSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSES 230

Query: 1152 ------------CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSK 1199
                        C GR+EV Y G+WG+V      T  A +VCRQLGCG            
Sbjct: 231  SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 290

Query: 1200 TGSGFMWVDDIQCPKTHISIWQC-------------------LSAPWERRISSPAEETWI 1240
             GSG + +DD++C      +W C                    SAP  R   +P+ +TW 
Sbjct: 291  QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR--PTPSPDTWP 348

Query: 1241 TCED---------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291
            T             +R+  G   C GRVE+ + GSWGTVCDDSWD ++A VVC+QLGCG 
Sbjct: 349  TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGW 408

Query: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            A +A  +A FGQG+G I LDD+RC G ES+LW C    W   +C H EDAGV CS
Sbjct: 409  ATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463



 Score =  138 bits (348), Expect = 3e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203

Query: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1241



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 1132 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1191

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 1192 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 1250

Query: 1017 P 1017
            P
Sbjct: 1251 P 1251



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1144 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1203

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1204 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1234


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  327 bits (837), Expect = 7e-89
 Identities = 203/587 (34%), Positives = 269/587 (45%), Gaps = 71/587 (12%)

Query: 583  LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGY 642
            LRL  G + C+GRLEV+  GRWGTVCDDGW+ + AAV C QL C  ++   G      G 
Sbjct: 20   LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 643  GKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGK 702
            G +WL +++C G+E  L            C H      ICS   D               
Sbjct: 80   GPVWLSELACRGNEGQLGL----------CHHRGWKAHICSHEED--------------- 114

Query: 703  VEVNVQGAVGILCANGWGMNIAEVVCRQLECGS--AIRVSREPHFTERTLHILMSNSGCT 760
                     G++CA     N  +     L+      + +   P   E  +      +G  
Sbjct: 115  --------AGVVCAGQRVANSRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNP 166

Query: 761  GGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRL--VGADMPCSGRVEVKHADTWRS 818
               +        + K T   L     L   A RQ RL  V     C+GR+EV H   W +
Sbjct: 167  QNASRKKSPRPKQAKSTRAPL-----LTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGT 221

Query: 819  VCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQ 878
            VCD  + L  A V CREL CG A++   G  FG G G  W +   C G E  L  CP   
Sbjct: 222  VCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSP 281

Query: 879  HPEDTCIHSREVGVVCSRYTD-VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVL 937
                 C HS + G+VC+     +RL +G   C G++E+   G WGS+CD  WD  DA V 
Sbjct: 282  WGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVA 341

Query: 938  CRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSV 997
            CR+L CG AL+  GG + GE S  +      C GNE+ L  C     G   C H      
Sbjct: 342  CRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGA 401

Query: 998  ICTG---SLTQPLFPCLANVSDPYLSA------------------VPEGSALICLE---- 1032
            +C G       P  P  +N S P  +A                   P  S  +  E    
Sbjct: 402  VCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPE 461

Query: 1033 --DKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSA- 1089
                +LRLV G S+C+GR+E++HD  WGT+CDD WD+ D+ VVC++LGCG       +A 
Sbjct: 462  AGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAG 521

Query: 1090 HFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
             FG G+GPIWLDD+ C G E+ L  CP+  WG+H+C H ED GV C+
Sbjct: 522  RFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  306 bits (783), Expect = 1e-82
 Identities = 217/668 (32%), Positives = 279/668 (41%), Gaps = 128/668 (19%)

Query: 690  LRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERT 749
            LRL  G   CAG++EV   G  G +C +GW +  A V CRQL CG A+       F E  
Sbjct: 20   LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 750  LHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADMPCSGRVE 809
              + +S   C G E  L  C    WK   C    +A ++               C+G+  
Sbjct: 80   GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVV---------------CAGQRV 124

Query: 810  VKHADTWRSVCDSDFSLHAANV--LCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGS 867
                D      DS   L  A    L  EL+      L        GN    + K      
Sbjct: 125  ANSRD------DSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPK 178

Query: 868  ETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDT 927
            +      P++                  R   +RLV+G  +C G++E+   G WG++CD 
Sbjct: 179  QAKSTRAPLLT-------------TGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDD 225

Query: 928  HWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAP 987
             WD  DA V CR+L CG AL+  GG   G  +  VW     C G E  L +C  +  G  
Sbjct: 226  GWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRS 285

Query: 988  PCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAG 1047
             C H     ++CTG                                 RLRL DG   CAG
Sbjct: 286  NCDHSEDAGLVCTGPAP------------------------------RLRLADGPHGCAG 315

Query: 1048 RVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTG 1107
            R+E++H G WG++CDD WDL DA V C++LGCG A  A   A FGEGSGPI LDDL C G
Sbjct: 316  RLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRG 375

Query: 1108 MESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLYSETETESCAGRLEVFYNGTWGSV 1167
             E                             TALR         C  R        WG  
Sbjct: 376  NE-----------------------------TALRF--------CPAR-------PWGQH 391

Query: 1168 GRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW 1227
               +   A  G VC  +  G   V   AP     S        + P T  S      AP 
Sbjct: 392  DCHHREDA--GAVCDGMPLGY--VPPTAPTDSNNSTPREAAS-RPPSTMTS-----QAPG 441

Query: 1228 ERRISSPAEETWITCED-------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEA 1280
               +S P     +  E        ++R+  G ++CSGR+E+WH   WGTVCDDSWD+ ++
Sbjct: 442  TAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDS 501

Query: 1281 EVVCQQLGCGSALAALRDAS-FGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKE 1339
             VVC++LGCG        A  FG G G IWLDD+ C G E+ L DC A PWG+ +C H E
Sbjct: 502  AVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNE 561

Query: 1340 DAGVRCSG 1347
            D GV C+G
Sbjct: 562  DVGVTCTG 569



 Score =  249 bits (637), Expect = 1e-65
 Identities = 153/424 (36%), Positives = 201/424 (47%), Gaps = 43/424 (10%)

Query: 262 LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGS 321
           LRL  G + C GR+E+   GRWGTVC   W+   A V C+QLGCG AL   G      G+
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 322 DVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSNNCSGR 381
             VWL  ++C GNE         G +   C H+   + ICS   D  +        C+G+
Sbjct: 80  GPVWLSELACRGNE---------GQLGL-CHHRGWKAHICSHEEDAGVV-------CAGQ 122

Query: 382 VEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRA-KPSNEARDIWINSISCTG 440
                 +   +  D        L +      P      R A  P N +R           
Sbjct: 123 RVANSRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRK---------- 172

Query: 441 NESALWDCTYDGKAKRTCFRRSDAGVICSDKADLD--LRLVGAHSPCYGRLEVKYQGEWG 498
                       K+ R    +S    + +  A     LRLV     C GRLEV + G WG
Sbjct: 173 ------------KSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWG 220

Query: 499 TVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHS 558
           TVC D W  R+AAV C++LGCG  +   G   F   +GP+W+DDV C G E  + DC  S
Sbjct: 221 TVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRS 280

Query: 559 GWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAA 618
            WG+ NC H ED  + C+G A   LRL  G + C+GRLEV+  GRWG+VCDD W+ + AA
Sbjct: 281 PWGRSNCDHSEDAGLVCTGPAP-RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAA 339

Query: 619 VVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDV 678
           V C +L C  ++   G      G G I LDD+ C G+E+ L  C    WG +DC H ED 
Sbjct: 340 VACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDA 399

Query: 679 GVIC 682
           G +C
Sbjct: 400 GAVC 403



 Score =  236 bits (602), Expect = 1e-61
 Identities = 130/329 (39%), Positives = 174/329 (52%), Gaps = 38/329 (11%)

Query: 1034 KRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGE 1093
            +RLRL DG   CAGR+E++H G WGT+CDDGWDL DA V C++LGCG A  A   A FGE
Sbjct: 18   ERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGE 77

Query: 1094 GSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLYSETETESCA 1153
            G+GP+WL +L C G E  L  C  RGW  H          ICS       + E     CA
Sbjct: 78   GAGPVWLSELACRGNEGQLGLCHHRGWKAH----------ICS-------HEEDAGVVCA 120

Query: 1154 GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCP 1213
            G+          +  R + T+ + G     L      ++ L+P ++       V     P
Sbjct: 121  GQRV--------ANSRDDSTSPLDGAPWPGL------LLELSPSTEEPL----VTHAPRP 162

Query: 1214 KTHISIWQCLSAPWERRISS---PAEETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTV 1270
              +        +P  ++  S   P   T    ++R+R+  G   C+GR+E+WH G WGTV
Sbjct: 163  AGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTV 222

Query: 1271 CDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPW 1330
            CDD WDL +A V C++LGCG ALAA   A FG G G +W+DD+ C G E  L DC   PW
Sbjct: 223  CDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPW 282

Query: 1331 GQSDCGHKEDAGVRCSGQSLKSLNASSGH 1359
            G+S+C H EDAG+ C+G + +   A   H
Sbjct: 283  GRSNCDHSEDAGLVCTGPAPRLRLADGPH 311



 Score =  229 bits (584), Expect = 1e-59
 Identities = 138/381 (36%), Positives = 183/381 (48%), Gaps = 64/381 (16%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRFGQAV 104
           LRLV+G   C+G +EV   G+WGTVCDDGW+   + V C++LGC  + A     RFG   
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257

Query: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSC 164
              G +W+DDV C G E AL +C    WG  NC H ED G+ C G A   LRL DG + C
Sbjct: 258 ---GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR-LRLADGPHGC 313

Query: 165 SGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILC 224
           +GR+EV    RWG++CDD W+L  AAV CR+LGC  +  + G         PI LDD+ C
Sbjct: 314 AGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRC 373

Query: 225 QGNELAL-------W---NCRHRGWGNHDC---------------SHNEDV--------- 250
           +GNE AL       W   +C HR      C               S+N            
Sbjct: 374 RGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPS 433

Query: 251 TLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCH 288
           T+T                        ++   +LRLV G ++C GR+E+    RWGTVC 
Sbjct: 434 TMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCD 493

Query: 289 HKWNNAAADVVCKQLGCGTALH-FAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
             W+   + VVC++LGCG              G+  +WLD V C G E+ L DC  +   
Sbjct: 494 DSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWG 553

Query: 348 NFDCLHQNDVSVICSDGADLE 368
             +C H  DV V C+    L+
Sbjct: 554 KHNCAHNEDVGVTCTGPPGLD 574



 Score =  196 bits (497), Expect = 2e-49
 Identities = 91/202 (45%), Positives = 123/202 (60%), Gaps = 3/202 (1%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            CAGRLEV++ G WG+V         A + CR+LGCG             G+G +W+DD+ 
Sbjct: 207  CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVG 266

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITCED---RIRVRGGDTECSGRVEIWHAGSWG 1268
            C     ++  C  +PW R     +E+  + C     R+R+  G   C+GR+E+WH G WG
Sbjct: 267  CGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWG 326

Query: 1269 TVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAK 1328
            +VCDD+WDL +A V C++LGCG ALAA   A FG+G+G I LDD+RC+GNE+ L  C A+
Sbjct: 327  SVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPAR 386

Query: 1329 PWGQSDCGHKEDAGVRCSGQSL 1350
            PWGQ DC H+EDAG  C G  L
Sbjct: 387  PWGQHDCHHREDAGAVCDGMPL 408



 Score =  179 bits (453), Expect = 2e-44
 Identities = 86/209 (41%), Positives = 116/209 (55%), Gaps = 1/209 (0%)

Query: 369 LRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEA 428
           LRL  G + C+GR+EV    +W T+CD  W    A V C++LGC  ++     A+    A
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGA 257

Query: 429 RDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVGAHSPCYGR 488
             +W++ + C G E AL DC      +  C    DAG++C+  A   LRL      C GR
Sbjct: 258 GPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR-LRLADGPHGCAGR 316

Query: 489 LEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGN 548
           LEV + G WG+VC D W  R+AAV C++LGCG  +   G  +F E SGPI LDD+ C GN
Sbjct: 317 LEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGN 376

Query: 549 ESNIWDCEHSGWGKHNCVHREDVIVTCSG 577
           E+ +  C    WG+H+C HRED    C G
Sbjct: 377 ETALRFCPARPWGQHDCHHREDAGAVCDG 405



 Score =  142 bits (358), Expect = 2e-33
 Identities = 57/105 (54%), Positives = 74/105 (70%)

Query: 1035 RLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEG 1094
            R+RL DG +RCAGR+E++H G WGT+CDD WDL DA V C +LGCG         H+G G
Sbjct: 771  RVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPG 830

Query: 1095 SGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFT 1139
            +GPIWLDD+ C G E+ L  CPS  WG+H+C H+ED G+ C+ +T
Sbjct: 831  TGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYT 875



 Score =  137 bits (346), Expect = 6e-32
 Identities = 58/109 (53%), Positives = 74/109 (67%)

Query: 1240 ITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDA 1299
            I   +R+R+  G   C+GR+E+WH G WGTVCDD WDL +A V C+QLGCG ALAA   A
Sbjct: 14   IQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGA 73

Query: 1300 SFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQ 1348
             FG+G G +WL ++ C+GNE  L  CH + W    C H+EDAGV C+GQ
Sbjct: 74   FFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQ 122



 Score =  136 bits (342), Expect = 2e-31
 Identities = 54/103 (52%), Positives = 72/103 (69%)

Query: 1245 RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQG 1304
            R+R+  G   C+GR+E+WHAG WGTVCDD+WDL +A V C +LGCG     +    +G G
Sbjct: 771  RVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPG 830

Query: 1305 TGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSG 1347
            TG IWLDDM CKG+E+ L DC +  WG+ +C H+ED G+ C+G
Sbjct: 831  TGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873



 Score =  123 bits (309), Expect = 1e-27
 Identities = 56/103 (54%), Positives = 68/103 (66%), Gaps = 1/103 (0%)

Query: 476 LRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMT-YFKEA 534
           LRLV   S C GRLEV +   WGTVC D W  R++AVVC++LGCG P         F   
Sbjct: 467 LRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWG 526

Query: 535 SGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG 577
           +GPIWLDDV C+G E+++ DC  + WGKHNC H EDV VTC+G
Sbjct: 527 AGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTG 569



 Score =  122 bits (307), Expect = 2e-27
 Identities = 52/102 (50%), Positives = 67/102 (65%)

Query: 476 LRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEAS 535
           +RL    + C GRLEV + G WGTVC D W  R+A V C +LGCGK     G T++   +
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 536 GPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG 577
           GPIWLDD+ C G+E+++ DC    WGKHNC H EDV +TC+G
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873



 Score =  115 bits (287), Expect = 4e-25
 Identities = 50/118 (42%), Positives = 69/118 (58%)

Query: 572 IVTCSGDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSII 631
           + T      + +RL  G NRC+GRLEV+  GRWGTVCDD W+ + A V C +L C     
Sbjct: 761 VSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRP 820

Query: 632 GMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDASDME 689
            +G  +   G G IWLDD+ C G E+ L  C +  WG ++C H EDVG+ C+  +D +
Sbjct: 821 RVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYD 878



 Score =  114 bits (285), Expect = 7e-25
 Identities = 50/100 (50%), Positives = 62/100 (62%)

Query: 155 LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVL 214
           LRL DG + C+GR+EV    RWGT+CDDGW+L  AAV CRQLGC  +  + G        
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 215 RPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
            P+WL ++ C+GNE  L  C HRGW  H CSH ED  + C
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC 119



 Score =  110 bits (275), Expect = 1e-23
 Identities = 53/118 (44%), Positives = 70/118 (59%), Gaps = 1/118 (0%)

Query: 145 VNCYGEANL-GLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFI 203
           V+  GE+ L  +RL DG N C+GR+EV    RWGT+CDD W+L  A V C +LGC     
Sbjct: 761 VSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRP 820

Query: 204 SSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLE 261
             G  +      PIWLDD+ C+G+E +L +C    WG H+C H EDV LTC   +D +
Sbjct: 821 RVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYD 878



 Score =  110 bits (274), Expect = 1e-23
 Identities = 55/111 (49%), Positives = 64/111 (57%), Gaps = 7/111 (6%)

Query: 47  ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSF----AMFRFGQ 102
           +LRLV G   CSG +EV    +WGTVCDD W+   S VVC++LGC        A  RFG 
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 103 AVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANL 153
                G IWLDDV C G E++L +C    WG HNC H EDVGV C G   L
Sbjct: 526 GA---GPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGL 573



 Score =  101 bits (252), Expect = 5e-21
 Identities = 48/106 (45%), Positives = 63/106 (59%), Gaps = 6/106 (5%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRFGQAV 104
           LRL +G   C+G +EV   G+WGTVCDDGW+   + V C+QLGC  + A      FG+  
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGE 150
              G +WL +++C GNE  L  C HR W +H C H ED GV C G+
Sbjct: 80  ---GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQ 122



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 48/111 (43%), Positives = 63/111 (56%), Gaps = 18/111 (16%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRH 107
           +RL +G   C+G +EV   G+WGTVCDD W+   +TV C +LGC         G+   R 
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGC---------GKVRPRV 822

Query: 108 GK---------IWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG 149
           GK         IWLDD+ C G+E++L +C    WG HNC H EDVG+ C G
Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 44/116 (37%), Positives = 60/116 (51%)

Query: 253 TCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFA 312
           T  +S    +RL  G NRC GR+E+   GRWGTVC   W+   A V C +LGCG      
Sbjct: 763 TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822

Query: 313 GLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLE 368
           G  H   G+  +WLD + C G+E+ L DC        +C H+ DV + C+   D +
Sbjct: 823 GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYD 878



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 41/104 (39%), Positives = 54/104 (51%)

Query: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
           RL      C+GR+EV HA  W +VCD ++ L  A V C EL CG         H+G G G
Sbjct: 773 RLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTG 832

Query: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD 899
             W +   C+GSE  L+ CP     +  C H  +VG+ C+ YTD
Sbjct: 833 PIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTD 876



 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 40/113 (35%), Positives = 59/113 (52%), Gaps = 9/113 (7%)

Query: 368 ELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSN- 426
           +LRL  G + CSGR+EV   ++W T+CD +W    + VVC++LGC     G ++  P+  
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCG----GPQQPDPAAG 521

Query: 427 ----EARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLD 475
                A  IW++ + C G E++L DC      K  C    D GV C+    LD
Sbjct: 522 RFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLD 574



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 38/107 (35%), Positives = 53/107 (49%)

Query: 369 LRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEA 428
           +RLADG N C+GR+EV    +W T+CD NW    A V C +LGC        +       
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 429 RDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLD 475
             IW++ + C G+E++L DC      K  C    D G+ C+   D D
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYD 878



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 36/102 (35%), Positives = 53/102 (51%)

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959
            VRL +G ++C G++E+   G WG++CD +WD  DA V C +L CG      G  + G  +
Sbjct: 772  VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTG 1001
              +W     C G+E+ L +C     G   C H   V + CTG
Sbjct: 832  GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873



 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 42/121 (34%), Positives = 62/121 (51%), Gaps = 9/121 (7%)

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALST--TGGKYIGE 957
            +RLV G S+C G++E+     WG++CD  WD  D+ V+CR+L CG         G++ G 
Sbjct: 467  LRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRF-GW 525

Query: 958  RSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDP 1017
             +  +W     C+G E+ L +C     G   C H   V V CTG       P L ++SDP
Sbjct: 526  GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGP------PGLDSISDP 579

Query: 1018 Y 1018
            +
Sbjct: 580  F 580



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 35/103 (33%), Positives = 51/103 (49%)

Query: 690 LRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERT 749
           +RL  G +RCAG++EV   G  G +C + W +  A V C +L CG       + H+   T
Sbjct: 772 VRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT 831

Query: 750 LHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
             I + + GC G EASL DC    W +  C    +  L C+ +
Sbjct: 832 GPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGY 874



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 33/95 (34%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGE----NGVVSLAPLSKTGSGFMWV 1207
            CAGRLEV++ G WG+V   N     A + C +LGCG+     G     P    G+G +W+
Sbjct: 781  CAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGP----GTGPIWL 836

Query: 1208 DDIQCPKTHISIWQCLSAPWERRISSPAEETWITC 1242
            DD+ C  +  S+  C S  W +      E+  +TC
Sbjct: 837  DDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871


>gi|18152779 scavenger receptor cysteine rich domain containing,
           group B (4 domains) [Homo sapiens]
          Length = 575

 Score =  324 bits (831), Expect = 3e-88
 Identities = 179/516 (34%), Positives = 240/516 (46%), Gaps = 94/516 (18%)

Query: 261 ELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSG 320
           ELRLVGG +RC GR+E+   G WG+VC   W+   A+VVC+QLGCG AL          G
Sbjct: 57  ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 321 SDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSD----------------- 363
              + LD V C G E+ L +C   G    +C H  DV+V+C +                 
Sbjct: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176

Query: 364 -------GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSV 416
                   ++  +RL  G+N C GRVE+     W T+CD +W    A VVC+QLGC  ++
Sbjct: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 417 FGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSD------ 470
             +  A        I ++++ C G E  L  C   G     C    DAG +C+       
Sbjct: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 471 ------------------------------------------KADLDLRLVGAHSPCYGR 488
                                                     K    LRLVG   PC GR
Sbjct: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356

Query: 489 LEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGN 548
           +EV + G WGTVC D W   +A V C++ GCG  +   G+ +F    GP+ LD+V C G 
Sbjct: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 549 ESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWG----------------------LRLV 586
           E+ + DC H GWG+HNC H ED    C+G    G                      LRLV
Sbjct: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476

Query: 587 GGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW 646
            G++RC GR+E+Y   RWGTVCDD W+ +AA V+C QL C  ++   G  +   G G I 
Sbjct: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536

Query: 647 LDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC 682
           LD+V C G+ES L  C +  W  ++C HSED  V+C
Sbjct: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  311 bits (797), Expect = 3e-84
 Identities = 188/519 (36%), Positives = 242/519 (46%), Gaps = 100/519 (19%)

Query: 47  ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFR---FGQA 103
           ELRLV G   C G +EV   G WG+VCDD W+   + VVC+QLGC  +  + R   FGQ 
Sbjct: 57  ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 104 VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---------------- 147
               G I LD+V C G E+AL EC  R WG HNC+H EDV V C                
Sbjct: 117 ---RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTS 173

Query: 148 --------YGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCP 199
                    G++   +RLV G N C GRVE+     WGT+CDD W L  AAVVCRQLGC 
Sbjct: 174 RAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCG 233

Query: 200 SSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV--------- 250
           ++  ++           I LD++ C+G E  L  C+  GWG H+C H+ED          
Sbjct: 234 AAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGP 293

Query: 251 -TLTCYDSSDL--------------------------------------ELRLVGGTNRC 271
            TLT   SS                                         LRLVGG   C
Sbjct: 294 PTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPC 353

Query: 272 MGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSC 331
            GRVE+   G WGTVC   W+ A A V C++ GCG AL   GL H   G   V LD V C
Sbjct: 354 RGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGC 413

Query: 332 SGNESFLWDCRHSGTVNFDCLHQNDVSVICS-----------DGA-----------DLEL 369
           +G E+ L DC H G    +C H  D   +C+           DG+           D  L
Sbjct: 414 AGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHL 473

Query: 370 RLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEAR 429
           RL +G++ C GRVE+ + ++W T+CD  W    A V+C+QLGC  ++     A       
Sbjct: 474 RLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRG 533

Query: 430 DIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVIC 468
            I ++++ C G ESAL  C++       C    DA V+C
Sbjct: 534 PILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  310 bits (794), Expect = 6e-84
 Identities = 178/516 (34%), Positives = 233/516 (45%), Gaps = 96/516 (18%)

Query: 475 DLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEA 534
           +LRLVG  S C GRLEV + G WG+VC D W   +A VVC+QLGCG  + V     F + 
Sbjct: 57  ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 535 SGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTC------------------- 575
            GPI LD+V C G E+ + +C   GWG HNC H EDV V C                   
Sbjct: 117 RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176

Query: 576 -----SGDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSI 630
                +G +   +RLVGG+N C GR+E+   G WGTVCDD W    AAVVC QL C +++
Sbjct: 177 PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 631 IGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC-------- 682
                     G G I LD+V C+G E  L +C++ GWG ++C H ED G +C        
Sbjct: 237 AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 683 ----------------------------------------SDASDMELRLVGGSSRCAGK 702
                                                   +      LRLVGG   C G+
Sbjct: 297 TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356

Query: 703 VEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGG 762
           VEV   G  G +C + W    A V CR+  CG A+  +   HF      +L+ N GC G 
Sbjct: 357 VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 763 EASLWDCIRWEWKQTACHLNMEASLICSAHRQ------------------------PRLV 798
           EA L DC    W Q  C  + +A  +C+   +                         RLV
Sbjct: 417 EARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLV 476

Query: 799 GADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTW 858
                C GRVE+     W +VCD  + L AA VLCR+L CG A++     HFG G G   
Sbjct: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536

Query: 859 AEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVC 894
            +  +C G E+ L LC  ++     C HS +  V+C
Sbjct: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  306 bits (785), Expect = 7e-83
 Identities = 187/525 (35%), Positives = 245/525 (46%), Gaps = 83/525 (15%)

Query: 897  YTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            + ++RLV G S+C G++E+   G WGS+CD  WD  DA V+CRQL CG AL        G
Sbjct: 55   FQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFG 114

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSL-TQPLFPCLANVS 1015
            +    +      C G E+ L  C     G   C H   V+V+C   L TQP    +    
Sbjct: 115  QGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSR 174

Query: 1016 DPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQ 1075
             P  + +P G +     +  +RLV G + C GRVEI H G WGT+CDD W L DA VVC+
Sbjct: 175  AP-PTTLPNGKS-----EGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCR 228

Query: 1076 KLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135
            +LGCG A  AT +A FG G+G I LD+++C G E  L  C S GWG H+C H EDAG +C
Sbjct: 229  QLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALC 288

Query: 1136 -----------------------------------SEFTAL-------------RLYSET 1147
                                               S  TAL             RL    
Sbjct: 289  AGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVG 348

Query: 1148 ETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGEN-GVVSLAPLSKTGSGFMW 1206
                C GR+EV + G WG+V   +   A A + CR+ GCG   G   L      G G + 
Sbjct: 349  GPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFG-YGRGPVL 407

Query: 1207 VDDIQCPKTHISIWQCLSAPWERRISSPAEETWITC------------------------ 1242
            +D++ C  T   +  C    W +      E+    C                        
Sbjct: 408  LDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR 467

Query: 1243 --EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDAS 1300
              +  +R+  G   C GRVE++    WGTVCDD+WDL  A V+C+QLGCG ALAA  +A 
Sbjct: 468  PRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAH 527

Query: 1301 FGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRC 1345
            FG G G I LD+++C+G ES L  C    W   +C H EDA V C
Sbjct: 528  FGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  290 bits (743), Expect = 5e-78
 Identities = 184/528 (34%), Positives = 235/528 (44%), Gaps = 93/528 (17%)

Query: 689  ELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTER 748
            ELRLVGG SRC G++EV   G+ G +C + W +  A VVCRQL CG A+ V R   F + 
Sbjct: 57   ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQG 116

Query: 749  TLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICS-------------AHRQP 795
               IL+ N  C G EA+L +C    W    C    + +++C                R P
Sbjct: 117  RGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAP 176

Query: 796  -------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAI 842
                         RLVG    C GRVE+ H+  W +VCD D+ L  A V+CR+L CG A+
Sbjct: 177  PTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAM 236

Query: 843  SLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVC-------- 894
            + +    FG G G    +   CEG E  LA C  +      C H  + G +C        
Sbjct: 237  AATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTL 296

Query: 895  ---------------------------SRYT---------------DVRLVNGKSQCDGQ 912
                                       SR T                +RLV G   C G+
Sbjct: 297  TALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGR 356

Query: 913  VEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGN 972
            VE+   G WG++CD  WD  DARV CR+  CG AL  TG  + G     V      C G 
Sbjct: 357  VEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGT 416

Query: 973  ESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICL- 1031
            E+ L +C     G   C H      +C G              +  L    +GS    + 
Sbjct: 417  EARLSDCFHLGWGQHNCGHHEDAGALCAGP------------EELGLQVQQDGSETTRVP 464

Query: 1032 ----EDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATV 1087
                 D  LRLV+G  RC GRVE+Y    WGT+CDD WDL  A V+C++LGCG A  A  
Sbjct: 465  TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524

Query: 1088 SAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135
             AHFG G GPI LD++ C G ES L  C    W  H+C H EDA V+C
Sbjct: 525  EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  290 bits (742), Expect = 7e-78
 Identities = 173/516 (33%), Positives = 235/516 (45%), Gaps = 69/516 (13%)

Query: 796  RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
            RLVG    C GR+EV H  +W SVCD D+ +  ANV+CR+L CG A+ +     FG+G G
Sbjct: 59   RLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRG 118

Query: 856  LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYT----------------- 898
                +  +C G E  L+ C         C H  +V V+C  +                  
Sbjct: 119  PILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPT 178

Query: 899  ---------DVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALST 949
                      VRLV G + C G+VEI   G WG++CD  W   DA V+CRQL CG A++ 
Sbjct: 179  TLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAA 238

Query: 950  TGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFP 1009
            T   + G  +  +     HC G E  L  CQ    G   C H      +C G L  P   
Sbjct: 239  TTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG-LGPPTLT 297

Query: 1010 CLANVS---------DPYLSAV-PEGSALICL----------EDKRLRLVDGDSRCAGRV 1049
             L + +         DP  + V P+ S    L          +  RLRLV G   C GRV
Sbjct: 298  ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 1050 EIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGME 1109
            E+ H G WGT+CDD WD +DA V C++ GCG A  AT   HFG G GP+ LD++ C G E
Sbjct: 358  EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 1110 SHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLY-----SETE---------------- 1148
            + L  C   GWGQH+C H EDAG +C+    L L      SET                 
Sbjct: 418  ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477

Query: 1149 -TESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWV 1207
                C GR+E++    WG+V         AG++CRQLGCG+            G G + +
Sbjct: 478  GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537

Query: 1208 DDIQCPKTHISIWQCLSAPWERRISSPAEETWITCE 1243
            D+++C     ++  C    W+      +E+  + C+
Sbjct: 538  DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQ 573



 Score =  276 bits (705), Expect = 1e-73
 Identities = 173/518 (33%), Positives = 226/518 (43%), Gaps = 98/518 (18%)

Query: 583  LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGY 642
            LRLVGG +RC GRLEV   G WG+VCDD W+   A VVC QL C  ++          G 
Sbjct: 58   LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 643  GKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSD------------------ 684
            G I LD+V C G E+ L  C + GWG ++C H EDV V+C +                  
Sbjct: 118  GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 685  ------ASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIR 738
                   S+  +RLVGG++ C G+VE+   G  G +C + WG+  A VVCRQL CG+A+ 
Sbjct: 178  TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 739  VSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP--- 795
             +    F   T HIL+ N  C GGE  L  C    W    C  + +A  +C+    P   
Sbjct: 238  ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 796  -----------------------------------------------RLVGADMPCSGRV 808
                                                           RLVG   PC GRV
Sbjct: 298  ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 809  EVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSE 868
            EV HA  W +VCD D+    A V CRE  CG A+  +   HFG G G    +   C G+E
Sbjct: 358  EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 869  THLALCPIVQHPEDTCIHSREVGVVCS------------------------RYTDVRLVN 904
              L+ C  +   +  C H  + G +C+                        R   +RLVN
Sbjct: 418  ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477

Query: 905  GKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWG 964
            G  +C+G+VE+ +   WG++CD  WD   A VLCRQL CG AL+  G  + G     +  
Sbjct: 478  GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537

Query: 965  HRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGS 1002
                C G ES L  C      A  C H    SV+C  S
Sbjct: 538  DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  266 bits (680), Expect = 1e-70
 Identities = 154/425 (36%), Positives = 201/425 (47%), Gaps = 82/425 (19%)

Query: 1001 GSLTQPLFPCLANVSDPYLSAVPEGSAL--ICLEDKRLRLVDGDSRCAGRVEIYHDGFWG 1058
            GS   P  P   +    +L  +P  SAL    L  + LRLV G SRC GR+E+ H G WG
Sbjct: 25   GSAAPPFLPQALS----FLLLLPLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWG 80

Query: 1059 TICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSR 1118
            ++CDD WD+ DA+VVC++LGCG+A        FG+G GPI LD++ C G E+ L +C SR
Sbjct: 81   SVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSR 140

Query: 1119 GWGQHDCRHKEDAGVICSEF------TALRLYSETETES------------------CAG 1154
            GWG H+C H ED  V+C EF      T   L S     +                  C G
Sbjct: 141  GWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQG 200

Query: 1155 RLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPK 1214
            R+E+ ++G WG+V   +     A +VCRQLGCG     +       G+G + +D++ C  
Sbjct: 201  RVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEG 260

Query: 1215 THISIWQCLSAPW-----------------------ERRISSPAEETWITCED------- 1244
                +  C S  W                           SS   E W    D       
Sbjct: 261  GEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVG 320

Query: 1245 ----------------------RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEV 1282
                                  R+R+ GG   C GRVE+ HAG WGTVCDD WD A+A V
Sbjct: 321  PQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARV 380

Query: 1283 VCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAG 1342
             C++ GCG AL A     FG G G + LD++ C G E+ L DC    WGQ +CGH EDAG
Sbjct: 381  ACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAG 440

Query: 1343 VRCSG 1347
              C+G
Sbjct: 441  ALCAG 445



 Score =  196 bits (497), Expect = 2e-49
 Identities = 96/232 (41%), Positives = 122/232 (52%), Gaps = 22/232 (9%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRH 107
           LRLV G GPC G VEV   G WGTVCDD W+   + V C++ GC  +      G      
Sbjct: 344 LRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGR 403

Query: 108 GKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLG------------- 154
           G + LD+V C G E+ L +C H  WG HNC H ED G  C G   LG             
Sbjct: 404 GPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRV 463

Query: 155 ---------LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISS 205
                    LRLV+G + C GRVE+   +RWGT+CDD W+L  A V+CRQLGC  +  + 
Sbjct: 464 PTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAP 523

Query: 206 GVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS 257
           G  +      PI LD++ C+G E AL  C H  W  H+C H+ED ++ C  S
Sbjct: 524 GEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  164 bits (416), Expect = 4e-40
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 28/232 (12%)

Query: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211
            C GRLEV + G+WGSV   +     A +VCRQLGCG    V        G G + +D+++
Sbjct: 67   CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126

Query: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITCED--------------------------- 1244
            C     ++ +C S  W        E+  + C++                           
Sbjct: 127  CRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSE 186

Query: 1245 -RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQ 1303
              +R+ GG   C GRVEI H+G WGTVCDD W L +A VVC+QLGCG+A+AA  +A FG 
Sbjct: 187  GSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY 246

Query: 1304 GTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNA 1355
            GTG I LD++ C+G E  L  C +  WG  +CGH EDAG  C+G    +L A
Sbjct: 247  GTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTA 298



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 49/103 (47%), Positives = 58/103 (56%)

Query: 45  DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAV 104
           D  LRLVNG   C G VE+    +WGTVCDD W+  A+ V+C+QLGC  + A        
Sbjct: 470 DGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFG 529

Query: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
              G I LD+V C G ESAL  C H  W +HNC H ED  V C
Sbjct: 530 PGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  306 bits (785), Expect = 7e-83
 Identities = 178/489 (36%), Positives = 243/489 (49%), Gaps = 41/489 (8%)

Query: 896  RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYI 955
            R+  VRL  GK++ +G VE+   G WG++C +HWD  DA V+C QL  G         + 
Sbjct: 166  RHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS 225

Query: 956  GERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVS 1015
            G   + ++     C G+E  +  C+  +     C      +V C+ S   P FP +    
Sbjct: 226  GLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFS-HGPTFPII---- 280

Query: 1016 DPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQ 1075
                                 RL  G S   GRVE+YH G WGT+CDD WD +DA V+C+
Sbjct: 281  ---------------------RLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR 319

Query: 1076 KLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC 1135
            +LG      A   A+FGEGSGP+ LD++ CTG E  + QCP   WG+H+C HKEDAGV C
Sbjct: 320  QLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC 379

Query: 1136 SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLA 1195
            +  T   +       S  GRLEV+Y G WG+V     T     +VCRQLG  + G  + A
Sbjct: 380  TPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGF-KYGKQASA 438

Query: 1196 PLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCED----------- 1244
               +  +G +W+DD+ C        QC    W R   S  E+  I C             
Sbjct: 439  NHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGF 498

Query: 1245 RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQG 1304
             +R+  G+ +  GRVE++  G WGT+CDD W   +A V+C+QLG      A   A FG+G
Sbjct: 499  PVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEG 558

Query: 1305 TGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALIL 1364
             G I +D+++C GNE  L DC  +  G+ +C H EDAGV C     K   AS       L
Sbjct: 559  KGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYFGKK---ASGNSNKESL 615

Query: 1365 SSIFGLLLL 1373
            SS+ GL LL
Sbjct: 616  SSVCGLRLL 624



 Score =  289 bits (740), Expect = 1e-77
 Identities = 160/437 (36%), Positives = 218/437 (49%), Gaps = 23/437 (5%)

Query: 369 LRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEA 428
           +RL  G N   G VEV     W T+C  +W +  A V+C QL         +        
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229

Query: 429 RDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLD---LRLVGAHSPC 485
             I+ +++ C G+E  +  C  D      C ++  A V CS         +RL G  S  
Sbjct: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289

Query: 486 YGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSC 545
            GR+E+ + G+WGTVC D+W   +A V+C+QLG       +   YF E SGP+ LD+V C
Sbjct: 290 EGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRC 349

Query: 546 IGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYFQGRWG 605
            GNE +I  C  S WG+HNC H+ED  V+C+      +RL GG     GRLEVY++G+WG
Sbjct: 350 TGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWG 409

Query: 606 TVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAST------GYGKIWLDDVSCDGDESDL 659
           TVCDDGW      VVC QL       G   G  ++        G IWLDDVSC G E+  
Sbjct: 410 TVCDDGWTELNTYVVCRQL-------GFKYGKQASANHFEESTGPIWLDDVSCSGKETRF 462

Query: 660 WSCRNSGWGNNDCSHSEDVGVICSDASD-------MELRLVGGSSRCAGKVEVNVQGAVG 712
             C    WG +DCSH EDV + C    +         +RL+ G ++  G+VEV + G  G
Sbjct: 463 LQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWG 522

Query: 713 ILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRW 772
            +C +GW    A V+CRQL      R     +F E    I + N  CTG E SL DCI+ 
Sbjct: 523 TICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQ 582

Query: 773 EWKQTACHLNMEASLIC 789
           +  +  C  + +A +IC
Sbjct: 583 DIGRHNCRHSEDAGVIC 599



 Score =  280 bits (715), Expect = 9e-75
 Identities = 159/471 (33%), Positives = 226/471 (47%), Gaps = 27/471 (5%)

Query: 131 EWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAA 190
           +WG  +C HG              +RL  G N   G VEV     WGT+C   W+ + A+
Sbjct: 159 DWGYCDCRHGS-------------VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDAS 205

Query: 191 VVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDV 250
           V+C QL      I+     S   L PI+  ++ C+G+E  +  C    W    C      
Sbjct: 206 VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265

Query: 251 TLTCYDSSDLE---LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT 307
            +TC  S       +RL GG++   GRVEL   G+WGTVC  +W++A A+V+C+QLG   
Sbjct: 266 AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325

Query: 308 ALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL 367
                   +   GS  V LD V C+GNE  +  C  S     +C H+ D  V C+   D 
Sbjct: 326 IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDG 385

Query: 368 ELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNE 427
            +RLA G  +  GR+EV    QW T+CD  W      VVC+QLG  +    S      + 
Sbjct: 386 VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASANHFEEST 445

Query: 428 ARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKAD-------LDLRLVG 480
              IW++ +SC+G E+    C+     +  C  R D  + C    +         +RL+ 
Sbjct: 446 G-PIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMD 504

Query: 481 AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWL 540
             +   GR+EV   G+WGT+C D W+ ++AAV+C+QLG   P     M YF E  GPI +
Sbjct: 505 GENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHV 564

Query: 541 DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNR 591
           D+V C GNE ++ DC     G+HNC H ED  V C     +G +  G SN+
Sbjct: 565 DNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICD---YFGKKASGNSNK 612



 Score =  268 bits (684), Expect = 4e-71
 Identities = 157/479 (32%), Positives = 220/479 (45%), Gaps = 43/479 (8%)

Query: 667  WGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEV 726
            WG  DC H               +RL GG +   G VEV   G  G +C++ W  + A V
Sbjct: 160  WGYCDCRHGS-------------VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASV 206

Query: 727  VCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEAS 786
            +C QL+ G      + P      + I  SN  C G E ++  C +  W+   C   M A+
Sbjct: 207  ICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAA 266

Query: 787  LICSAHRQP-----RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDA 841
            + CS    P     RL G      GRVE+ HA  W +VCD  +    A V+CR+L     
Sbjct: 267  VTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326

Query: 842  ISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD-- 899
                   +FG+G+G    ++ +C G+E  +  CP     E  C H  + GV C+  TD  
Sbjct: 327  AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGV 386

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959
            +RL  GK   +G++E+   G WG++CD  W   +  V+CRQL            +  E +
Sbjct: 387  IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYG-KQASANHFEEST 445

Query: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019
              +W     C G E+    C     G   C H   VS+ C                    
Sbjct: 446  GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC-------------------- 485

Query: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079
               P G          +RL+DG+++  GRVE++ +G WGTICDDGW   DA V+C++LG 
Sbjct: 486  --YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGY 543

Query: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEF 1138
                 A   A+FGEG GPI +D++ CTG E  L  C  +  G+H+CRH EDAGVIC  F
Sbjct: 544  KGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYF 602



 Score =  267 bits (682), Expect = 6e-71
 Identities = 154/440 (35%), Positives = 210/440 (47%), Gaps = 29/440 (6%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQL---------GCPFSFAMF 98
           +RL  G     GTVEV   G WGTVC   W+ + ++V+C QL           PFS    
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS---- 225

Query: 99  RFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---YGEANLGL 155
             G  +     I+  +V C G+E  +  C+   W    C       V C   +G     +
Sbjct: 226 --GLGLI---PIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPII 280

Query: 156 RLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLR 215
           RL  G++   GRVE+    +WGT+CDD W+   A V+CRQLG      +           
Sbjct: 281 RLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGSG 340

Query: 216 PIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRV 275
           P+ LD++ C GNEL++  C    WG H+C H ED  ++C   +D  +RL GG     GR+
Sbjct: 341 PVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRL 400

Query: 276 ELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNE 335
           E+  +G+WGTVC   W      VVC+QLG       A   H +  +  +WLD VSCSG E
Sbjct: 401 EVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQ-ASANHFEESTGPIWLDDVSCSGKE 459

Query: 336 SFLWDCRHSGTVNFDCLHQNDVSVICSDGAD-------LELRLADGSNNCSGRVEVRIHE 388
           +    C        DC H+ DVS+ C  G +         +RL DG N   GRVEV I+ 
Sbjct: 460 TRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSLGFPVRLMDGENKKEGRVEVFING 519

Query: 389 QWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDC 448
           QW TICD  W ++ A V+C+QLG          A        I ++++ CTGNE +L DC
Sbjct: 520 QWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579

Query: 449 TYDGKAKRTCFRRSDAGVIC 468
                 +  C    DAGVIC
Sbjct: 580 IKQDIGRHNCRHSEDAGVIC 599



 Score =  252 bits (644), Expect = 2e-66
 Identities = 137/368 (37%), Positives = 183/368 (49%), Gaps = 22/368 (5%)

Query: 17  CHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDG 76
           C Q + +A VTC       F I         +RL  G     G VE+   GQWGTVCDD 
Sbjct: 259 CPQKM-AAAVTCSFSHGPTFPI---------IRLAGGSSVHEGRVELYHAGQWGTVCDDQ 308

Query: 77  WNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHN 136
           W+   + V+C+QLG       +         G + LD+V C GNE ++ +C    WG HN
Sbjct: 309 WDDADAEVICRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHN 368

Query: 137 CYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQL 196
           C H ED GV+C    +  +RL  G  S  GR+EV ++ +WGT+CDDGW      VVCRQL
Sbjct: 369 CGHKEDAGVSCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQL 428

Query: 197 GCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYD 256
           G      +S   +      PIWLDD+ C G E     C  R WG HDCSH EDV++ CY 
Sbjct: 429 GFKYGKQAS-ANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYP 487

Query: 257 SSD-------LELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTAL 309
             +         +RL+ G N+  GRVE+ I G+WGT+C   W +  A V+C+QLG     
Sbjct: 488 GGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPA 547

Query: 310 HFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLEL 369
               + +   G   + +D V C+GNE  L DC        +C H  D  VIC    D   
Sbjct: 548 RARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC----DYFG 603

Query: 370 RLADGSNN 377
           + A G++N
Sbjct: 604 KKASGNSN 611



 Score =  244 bits (622), Expect = 6e-64
 Identities = 154/466 (33%), Positives = 212/466 (45%), Gaps = 24/466 (5%)

Query: 451 DGKAKRTCFRRSDAGVICSDKADL---DLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWST 507
           DG  +  CF     G +     D     +RL G  +   G +EV   G WGTVC   W  
Sbjct: 142 DGAGRPWCFYGDARGKVDWGYCDCRHGSVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDD 201

Query: 508 RNAAVVCKQLGCGKPMHVFGMTYFKEASG----PIWLDDVSCIGNESNIWDCEHSGWGKH 563
            +A+V+C QL  G      G+      SG    PI+  +V C G+E NI  CE   W   
Sbjct: 202 SDASVICHQLQLGGK----GIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGG 257

Query: 564 NCVHREDVIVTCS---GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVV 620
            C  +    VTCS   G     +RL GGS+   GR+E+Y  G+WGTVCDD W+   A V+
Sbjct: 258 VCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVI 317

Query: 621 CSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGV 680
           C QL                G G + LD+V C G+E  +  C  S WG ++C H ED GV
Sbjct: 318 CRQLGLSGIAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGV 377

Query: 681 ICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVS 740
            C+  +D  +RL GG     G++EV  +G  G +C +GW      VVCRQL      + S
Sbjct: 378 SCTPLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQAS 437

Query: 741 REPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLIC----SAHRQP- 795
              HF E T  I + +  C+G E     C R +W +  C    + S+ C      HR   
Sbjct: 438 AN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHRLSL 496

Query: 796 ----RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFG 851
               RL+  +    GRVEV     W ++CD  ++   A V+CR+L            +FG
Sbjct: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556

Query: 852 KGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY 897
           +G G    +  +C G+E  LA C         C HS + GV+C  +
Sbjct: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVICDYF 602



 Score =  160 bits (406), Expect = 6e-39
 Identities = 86/235 (36%), Positives = 123/235 (52%), Gaps = 22/235 (9%)

Query: 1120 WGQHDCRHKEDAGVICSEFTALRLY-SETETESCAGRLEVFYNGTWGSVGRRNITTAIAG 1178
            WG  DCRH            ++RL   + E E   G +EV+ +G WG+V   +   + A 
Sbjct: 160  WGYCDCRH-----------GSVRLRGGKNEFE---GTVEVYASGVWGTVCSSHWDDSDAS 205

Query: 1179 IVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEET 1238
            ++C QL  G  G+    P S  G   ++  +++C     +I  C    W+  +       
Sbjct: 206  VICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAA 265

Query: 1239 WITCE-------DRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291
             +TC          IR+ GG +   GRVE++HAG WGTVCDD WD A+AEV+C+QLG   
Sbjct: 266  AVTCSFSHGPTFPIIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG 325

Query: 1292 ALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
               A   A FG+G+G + LD++RC GNE  +  C    WG+ +CGHKEDAGV C+
Sbjct: 326  IAKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT 380


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  265 bits (676), Expect = 3e-70
 Identities = 139/327 (42%), Positives = 178/327 (54%), Gaps = 16/327 (4%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRFGQAV 104
           +RLV G   C G VEV+ +GQWGTVCDDGW+     V+C++LGC  +        +    
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC------YGEANLGLRLV 158
            +  K+ +  VSC G E  L +C+  E   ++C H ED G +C      +     G+RL 
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPEGVRLA 141

Query: 159 DGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLR-PI 217
           DG   C GRVEVK Q +W T+C  GW+L  A VVCRQLGC  + ++    N  A  R PI
Sbjct: 142 DGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPI 201

Query: 218 WLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVEL 277
           WL  + C G E  L +C    WG + C+H+ED  + C D  D  LRLVGG N C GR+E+
Sbjct: 202 WLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFD--LRLVGGDNLCSGRLEV 259

Query: 278 KIQGRWGTVCHHKWNNAAADVVCKQLGCGTAL--HFAGLPHLQSGSDVVWLDGVSCSGNE 335
             +G WG+VC   W      VVCKQLGCG +L   F        G   +WLD V CSG E
Sbjct: 260 LHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEE 319

Query: 336 SFLWDCRHSGTVNFDCLHQNDVSVICS 362
             L  C+H      DC HQ DV+VICS
Sbjct: 320 QSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  256 bits (653), Expect = 1e-67
 Identities = 135/331 (40%), Positives = 178/331 (53%), Gaps = 22/331 (6%)

Query: 262 LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPH----- 316
           +RLVGG +RC GRVE++ +G+WGTVC   W+     V+C++LGCG A   +G P      
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAA---SGTPSGILYE 80

Query: 317 -LQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL------EL 369
                   V +  VSC+G E  L  C       +DC H  D    C +           +
Sbjct: 81  PPAEKEQKVLIQSVSCTGTEDTLAQCEQEEV--YDCSHDEDAGASCENPESSFSPVPEGV 138

Query: 370 RLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRA-KPSNEA 428
           RLADG  +C GRVEV+   QW+T+C   W    A VVC+QLGC  +V   +R  K +   
Sbjct: 139 RLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGR 198

Query: 429 RDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVGAHSPCYGR 488
           + IW++ +SC+G E+ L DC      K TC    D  V C D    DLRLVG  + C GR
Sbjct: 199 KPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDP--FDLRLVGGDNLCSGR 256

Query: 489 LEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPM--HVFGMTYFKEASGPIWLDDVSCI 546
           LEV ++G WG+VC D W  +   VVCKQLGCGK +         +    G IWLD+V C 
Sbjct: 257 LEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCS 316

Query: 547 GNESNIWDCEHSGWGKHNCVHREDVIVTCSG 577
           G E ++  C+H  WG H+C H+EDV V CSG
Sbjct: 317 GEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score =  247 bits (631), Expect = 5e-65
 Identities = 131/327 (40%), Positives = 181/327 (55%), Gaps = 18/327 (5%)

Query: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHF---G 1092
            +RLV G  RC GRVE+   G WGT+CDDGWD+ D  V+C++LGCG A        +    
Sbjct: 24   VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 1093 EGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC----SEFTALR--LYSE 1146
            E    + +  ++CTG E  L QC       +DC H EDAG  C    S F+ +   +   
Sbjct: 84   EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPEGVRLA 141

Query: 1147 TETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGF-- 1204
                 C GR+EV +   W +V +   +   A +VCRQLGCG   V++    +K   G   
Sbjct: 142  DGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGR-AVLTQKRCNKHAYGRKP 200

Query: 1205 MWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDR--IRVRGGDTECSGRVEIW 1262
            +W+  + C     ++  C S PW +   +  E+TW+ CED   +R+ GGD  CSGR+E+ 
Sbjct: 201  IWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLEVL 260

Query: 1263 HAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA-ALRDAS-FGQGTGTIWLDDMRCKGNES 1320
            H G WG+VCDD+W   E +VVC+QLGCG +L+ + RD   +G G G IWLD++RC G E 
Sbjct: 261  HKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQ 320

Query: 1321 FLWDCHAKPWGQSDCGHKEDAGVRCSG 1347
             L  C  + WG  DC H+ED  V CSG
Sbjct: 321  SLEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score =  223 bits (568), Expect = 1e-57
 Identities = 127/329 (38%), Positives = 174/329 (52%), Gaps = 18/329 (5%)

Query: 154 GLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC-PSSFISSGVVNSPA 212
           G+RLV G + C GRVEV+ + +WGT+CDDGW++   AV+CR+LGC  +S   SG++  P 
Sbjct: 23  GVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPP 82

Query: 213 VLR--PIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC------YDSSDLELRL 264
             +   + +  + C G E  L  C       +DCSH+ED   +C      +      +RL
Sbjct: 83  AEKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEGVRL 140

Query: 265 VGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQS-GSDV 323
             G   C GRVE+K Q +W TVC   W+  AA VVC+QLGCG A+      +  + G   
Sbjct: 141 ADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKP 200

Query: 324 VWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSNNCSGRVE 383
           +WL  +SCSG E+ L DC         C H  D  V C D  D  LRL  G N CSGR+E
Sbjct: 201 IWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFD--LRLVGGDNLCSGRLE 258

Query: 384 VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSV---FGSRRAKPSNEARDIWINSISCTG 440
           V     W ++CD NW  ++  VVCKQLGC  S+   F  R+       R IW++++ C+G
Sbjct: 259 VLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGR-IWLDNVRCSG 317

Query: 441 NESALWDCTYDGKAKRTCFRRSDAGVICS 469
            E +L  C +       C  + D  VICS
Sbjct: 318 EEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  212 bits (540), Expect = 2e-54
 Identities = 123/330 (37%), Positives = 164/330 (49%), Gaps = 22/330 (6%)

Query: 582 GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDC------PSSIIGMGL 635
           G+RLVGG +RC GR+EV  +G+WGTVCDDGW+ K  AV+C +L C      PS I+    
Sbjct: 23  GVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGIL---Y 79

Query: 636 GNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDASDM------E 689
              +    K+ +  VSC G E  L  C        DCSH ED G  C +           
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEG 137

Query: 690 LRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR--EPHFTE 747
           +RL  G   C G+VEV  Q     +C  GW +  A+VVCRQL CG A+   +    H   
Sbjct: 138 VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 748 RTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADMPCSGR 807
           R   I +S   C+G EA+L DC    W +  C+ + +  + C      RLVG D  CSGR
Sbjct: 198 RK-PIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGR 256

Query: 808 VEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDH--FGKGNGLTWAEKFQCE 865
           +EV H   W SVCD ++      V+C++L CG ++S S  D   +G G G  W +  +C 
Sbjct: 257 LEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCS 316

Query: 866 GSETHLALCPIVQHPEDTCIHSREVGVVCS 895
           G E  L  C         C H  +V V+CS
Sbjct: 317 GEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  207 bits (528), Expect = 5e-53
 Identities = 123/356 (34%), Positives = 163/356 (45%), Gaps = 49/356 (13%)

Query: 796  RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHF---GK 852
            RLVG    C GRVEV+    W +VCD  + +    VLCREL CG A     G  +    +
Sbjct: 25   RLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAE 84

Query: 853  GNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD--------VRLVN 904
                   +   C G+E  LA C   Q     C H  + G  C             VRL +
Sbjct: 85   KEQKVLIQSVSCTGTEDTLAQCE--QEEVYDCSHDEDAGASCENPESSFSPVPEGVRLAD 142

Query: 905  GKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTG--GKYIGERSVRV 962
            G   C G+VE+     W ++C T W    A+V+CRQL CG A+ T     K+   R   +
Sbjct: 143  GPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKP-I 201

Query: 963  WGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAV 1022
            W  +  C G E+ L +C     G   C H     V C                DP+    
Sbjct: 202  WLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC---------------EDPF---- 242

Query: 1023 PEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVA 1082
                         LRLV GD+ C+GR+E+ H G WG++CDD W   +  VVC++LGCG +
Sbjct: 243  ------------DLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKS 290

Query: 1083 FNATVSAH--FGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
             + +      +G G G IWLD++ C+G E  L QC  R WG HDC H+ED  VICS
Sbjct: 291  LSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  199 bits (506), Expect = 2e-50
 Identities = 119/332 (35%), Positives = 167/332 (50%), Gaps = 18/332 (5%)

Query: 685  ASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIR----VS 740
            AS   +RLVGG  RC G+VEV  +G  G +C +GW +    V+CR+L CG+A      + 
Sbjct: 19   ASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGIL 78

Query: 741  REPHFTERTLHILMSNSGCTGGEASL--------WDCIRWEWKQTACHLNMEASLICSAH 792
             EP   E+   +L+ +  CTG E +L        +DC   E    +C  N E+S      
Sbjct: 79   YEPP-AEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCE-NPESSF-SPVP 135

Query: 793  RQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVG-DHFG 851
               RL      C GRVEVKH + W +VC + +SL AA V+CR+L CG A+      +   
Sbjct: 136  EGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHA 195

Query: 852  KGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDG 911
             G    W  +  C G E  L  CP     ++TC H  +  V C    D+RLV G + C G
Sbjct: 196  YGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSG 255

Query: 912  QVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTT--GGKYIGERSVRVWGHRFHC 969
            ++E+   G WGS+CD +W  ++ +V+C+QL CG +LS +    K  G    R+W     C
Sbjct: 256  RLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRC 315

Query: 970  LGNESLLDNCQMTVLGAPPCIHGNTVSVICTG 1001
             G E  L+ CQ    G   C H   V+VIC+G
Sbjct: 316  SGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score =  191 bits (486), Expect = 3e-48
 Identities = 99/220 (45%), Positives = 123/220 (55%), Gaps = 7/220 (3%)

Query: 39  SSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFS-FAM 97
           SSF+     +RL +G G C G VEVK Q QW TVC  GW+  A+ VVC+QLGC  +    
Sbjct: 129 SSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQ 188

Query: 98  FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRL 157
            R  +       IWL  +SC G E+ L +C    WG + C H ED  V C  E    LRL
Sbjct: 189 KRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--EDPFDLRL 246

Query: 158 VDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISS---GVVNSPAVL 214
           V G+N CSGR+EV  +  WG++CDD W      VVC+QLGC  S   S        P V 
Sbjct: 247 VGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVG 306

Query: 215 RPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
           R IWLD++ C G E +L  C+HR WG HDC+H EDV + C
Sbjct: 307 R-IWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVIC 345



 Score =  114 bits (284), Expect = 9e-25
 Identities = 57/108 (52%), Positives = 68/108 (62%), Gaps = 8/108 (7%)

Query: 47  ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFA-MFR----FG 101
           +LRLV GD  CSG +EV  +G WG+VCDD W      VVCKQLGC  S +  FR    +G
Sbjct: 243 DLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYG 302

Query: 102 QAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG 149
             V   G+IWLD+V C G E +L +CQHR WG H+C H EDV V C G
Sbjct: 303 PGV---GRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  235 bits (600), Expect = 2e-61
 Identities = 115/236 (48%), Positives = 138/236 (58%), Gaps = 23/236 (9%)

Query: 471 KADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTY 530
           ++ L LRLV     C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   
Sbjct: 13  ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 72

Query: 531 FKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG------------- 577
           F + SGPI LDDV C GNES +W C H+GW  HNC H ED  V CSG             
Sbjct: 73  FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWP 132

Query: 578 ----------DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCP 627
                     +++  LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C 
Sbjct: 133 SRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 192

Query: 628 SSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
            +    G      G G I LDDV C G ES LWSC N+GW +++C H ED GVICS
Sbjct: 193 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  220 bits (561), Expect = 7e-57
 Identities = 111/240 (46%), Positives = 137/240 (57%), Gaps = 29/240 (12%)

Query: 44  TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSF---AMFRF 100
           + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++       RF
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 101 GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149
           GQ     G I LDDV C GNES LW C H  W SHNC H ED GV C G           
Sbjct: 74  GQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130

Query: 150 ------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLG 197
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLG
Sbjct: 131 WPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 190

Query: 198 CPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS 257
           C  +  + G         PI LDD+ C G+E  LW+C + GW +H+C H+ED  + C  S
Sbjct: 191 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250



 Score =  218 bits (556), Expect = 3e-56
 Identities = 109/237 (45%), Positives = 142/237 (59%), Gaps = 6/237 (2%)

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959
            +RLVNG  +C G+VE+   G WG++CD  WD  DA V+CRQL CG A+   G    G+ S
Sbjct: 18   LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77

Query: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019
              +      C GNES L +C      +  C H     VIC+G   +      +  S    
Sbjct: 78   GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137

Query: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079
            S +   S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGC
Sbjct: 138  SPIGPESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 191

Query: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            G A +A  +A FG+GSGPI LDD+ C+G ES+LW CP+ GW  H+C H EDAGVICS
Sbjct: 192  GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  214 bits (546), Expect = 4e-55
 Identities = 104/236 (44%), Positives = 135/236 (57%), Gaps = 23/236 (9%)

Query: 150 EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVN 209
           E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLGC  + ++ G   
Sbjct: 13  ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 72

Query: 210 SPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY-------------- 255
                 PI LDD+ C GNE  LW+C H GW +H+C H+ED  + C               
Sbjct: 73  FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWP 132

Query: 256 ---------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCG 306
                      S L LRLV G +RC GRVE+  +G WGTVC   W+   A+VVC+QLGCG
Sbjct: 133 SRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG 192

Query: 307 TALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
            A    G      GS  + LD V CSG+ES+LW C ++G ++ +C H  D  VICS
Sbjct: 193 WATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  204 bits (520), Expect = 4e-52
 Identities = 100/236 (42%), Positives = 128/236 (54%), Gaps = 23/236 (9%)

Query: 365 ADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKP 424
           + L LRL +G + C GRVEV     W T+CD +W    A VVC+QLGC +++     A+ 
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 425 SNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSD-------------- 470
              +  I ++ + C+GNES LW C ++G     C    DAGVICS               
Sbjct: 74  GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPS 133

Query: 471 ---------KADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGK 521
                    ++ L LRLV     C GR+EV Y+G WGTVC D W T +A VVC+QLGCG 
Sbjct: 134 RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 193

Query: 522 PMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSG 577
                G   F + SGPI LDDV C G+ES +W C ++GW  HNC H ED  V CSG
Sbjct: 194 ATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSG 249



 Score =  194 bits (494), Expect = 4e-49
 Identities = 97/235 (41%), Positives = 126/235 (53%), Gaps = 23/235 (9%)

Query: 258 SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHL 317
           S L LRLV G +RC GRVE+  +G WGTVC   W+   A+VVC+QLGCG A+   G    
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 318 QSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDG------------- 364
             GS  + LD V CSGNES+LW C H+G ++ +C H  D  VICS G             
Sbjct: 74  GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPS 133

Query: 365 ----------ADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPF 414
                     + L LRL +G + C GRVEV     W T+CD +W    A VVC+QLGC +
Sbjct: 134 RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 193

Query: 415 SVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
           +      A+    +  I ++ + C+G+ES LW C  +G     C    DAGVICS
Sbjct: 194 ATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  189 bits (481), Expect = 1e-47
 Identities = 100/240 (41%), Positives = 129/240 (53%), Gaps = 27/240 (11%)

Query: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGS 1095
            LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LGCG A  A  +A FG+GS
Sbjct: 18   LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77

Query: 1096 GPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS------------------- 1136
            GPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS                   
Sbjct: 78   GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137

Query: 1137 ------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENG 1190
                     ALRL +  +   C GR+EV Y G+WG+V   +  T  A +VCRQLGCG   
Sbjct: 138  SPIGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 195

Query: 1191 VVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRG 1250
                      GSG + +DD++C      +W C +  W        E+  + C     V G
Sbjct: 196  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAG 255



 Score =  178 bits (451), Expect = 4e-44
 Identities = 91/225 (40%), Positives = 119/225 (52%), Gaps = 27/225 (12%)

Query: 1150 ESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDD 1209
            + C GR+EV Y G+WG+V   +  T  A +VCRQLGCG   +         GSG + +DD
Sbjct: 25   DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD 84

Query: 1210 IQCPKTHISIWQCLSAPWERRISSPAEETWITCED------------------------- 1244
            ++C      +W C    W       +E+  + C                           
Sbjct: 85   VRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCSPIGPES 144

Query: 1245 --RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFG 1302
               +R+  G   C GRVE+ + GSWGTVCDDSWD  +A VVC+QLGCG A +A  +A FG
Sbjct: 145  SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFG 204

Query: 1303 QGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSG 1347
            QG+G I LDD+RC G+ES+LW C    W   +CGH EDAGV CSG
Sbjct: 205  QGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSG 249



 Score =  146 bits (369), Expect = 1e-34
 Identities = 87/253 (34%), Positives = 117/253 (46%), Gaps = 31/253 (12%)

Query: 796  RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
            RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+       FG+G+G
Sbjct: 19   RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSG 78

Query: 856  LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS-------------------- 895
                +  +C G+E++L  CP        C HS + GV+CS                    
Sbjct: 79   PIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCS 138

Query: 896  -----RYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTT 950
                     +RLVNG  +C G+VE+   G WG++CD  WD  DA V+CRQL CG A S  
Sbjct: 139  PIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAP 198

Query: 951  GGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLT------ 1004
            G    G+ S  +      C G+ES L +C      +  C H     VIC+GS        
Sbjct: 199  GNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAGPRR 258

Query: 1005 QPLFPCLANVSDP 1017
                P LA   DP
Sbjct: 259  PQEMPGLARAQDP 271



 Score =  143 bits (360), Expect = 1e-33
 Identities = 82/235 (34%), Positives = 114/235 (48%), Gaps = 25/235 (10%)

Query: 686 SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHF 745
           S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCRQL CG A+       F
Sbjct: 14  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 73

Query: 746 TERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSA--HRQP-------- 795
            + +  I++ +  C+G E+ LW C    W    C  + +A +ICS    R P        
Sbjct: 74  GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPS 133

Query: 796 ---------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840
                          RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG 
Sbjct: 134 RFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 193

Query: 841 AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
           A S      FG+G+G    +  +C G E++L  CP        C H  + GV+CS
Sbjct: 194 ATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248



 Score =  139 bits (349), Expect = 3e-32
 Identities = 63/100 (63%), Positives = 73/100 (73%), Gaps = 1/100 (1%)

Query: 1248 VRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGT 1307
            V GGD  C GRVE+ + GSWGTVCDDSWD  +A VVC+QLGCG A+ A  +A FGQG+G 
Sbjct: 21   VNGGD-RCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGP 79

Query: 1308 IWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSG 1347
            I LDD+RC GNES+LW C    W   +CGH EDAGV CSG
Sbjct: 80   IVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSG 119


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  226 bits (575), Expect = 2e-58
 Identities = 153/486 (31%), Positives = 222/486 (45%), Gaps = 62/486 (12%)

Query: 56  PCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDV 115
           P  G VE++  G+WGT+CDD +   A+ ++C++LG   +       +     G+IWLD++
Sbjct: 53  PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112

Query: 116 SCYGNESALWECQHREWGSHNCYHGEDVGVNC-------YGEANL------------GLR 156
           SC G E ++ EC  R WG+ +C H ED GV C       + ++N+             +R
Sbjct: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172

Query: 157 LVDGNNS-----CSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSP 211
              G          G VEV+  + W  +CD GW+ + + VVC  LG PS    +      
Sbjct: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232

Query: 212 AVLRP---IWLDDILCQGNELALWNCRHRGWGNHD---CSHNEDVTLTC-----YDSS-- 258
              R      L  + C G E  L  C    +  +D   C       ++C     Y +S  
Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292

Query: 259 -----------DLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT 307
                      +  +RL GG +   GRVE+     WGTVC  KW+  AA VVC++LG G+
Sbjct: 293 QKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352

Query: 308 ALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS---DG 364
           A        +  G   + L  V CSG E  LW C H      DC H  D  V C+    G
Sbjct: 353 AREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTG 412

Query: 365 ADLELRLADGSNNCSGRVEVRIHE----QWWTICDQNWKNEQALVVCKQLGCPFSVFGSR 420
           A+  +RL+ G +   GRVEV+I      +W  IC  +W   +A+V C+QLG  ++  G +
Sbjct: 413 AETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQ 472

Query: 421 RA--KPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFR---RSDAGVICSDKADLD 475
                 S    ++ ++ + CTG E +L  C + G    TC R   R  AGVICS+ A  D
Sbjct: 473 ETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG-THITCKRTGTRFTAGVICSETAS-D 530

Query: 476 LRLVGA 481
           L L  A
Sbjct: 531 LLLHSA 536



 Score =  206 bits (523), Expect = 2e-52
 Identities = 128/352 (36%), Positives = 170/352 (48%), Gaps = 52/352 (14%)

Query: 1047 GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCT 1106
            GRVEI   G WGTICDD + L  AH++C++LG   A   T SA +G G+G IWLD+L+C+
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 1107 GMESHLWQCPSRGWGQHDCRHKEDAGVIC--------SEFTALRLYSETETESCA----- 1153
            G E  + +C SRGWG  DC H EDAGVIC        S+   + +    + E        
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 1154 -----------GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC---------------- 1186
                       G +EV     W  V  +  +   + +VC  LG                 
Sbjct: 176  GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235

Query: 1187 ------GENGVVSL---APLSKTGSGFMWVDDI-QCPKTHISIWQCLSAPWERRISSPA- 1235
                  G +GV  +   A LS     F   +D  +CP    ++  C+  P     S    
Sbjct: 236  RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295

Query: 1236 -EETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA 1294
             +++    E R+R++GG     GRVE+  A +WGTVCD  WDL  A VVC++LG GSA  
Sbjct: 296  QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355

Query: 1295 ALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            AL  A  GQG G I L ++RC G E  LW C  K     DC H +DAGVRC+
Sbjct: 356  ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407



 Score =  205 bits (522), Expect = 2e-52
 Identities = 150/508 (29%), Positives = 214/508 (42%), Gaps = 73/508 (14%)

Query: 594  GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCD 653
            GR+E+   G WGT+CDD +  +AA ++C +L    +           G G+IWLD++SC 
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 654  GDESDLWSCRNSGWGNNDCSHSEDVGVICSD-------------------ASDMELRLVG 694
            G E  +  C + GWGN+DC+H ED GVIC D                     ++ +R   
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 695  GSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR-------- 741
            G  R       G VEV +      +C  GW  + + VVC  L   S  RV+         
Sbjct: 176  GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235

Query: 742  ----------------EPHFTERTLHILMSN--SGCTGGEASLWDCIRWEWKQTACHLNM 783
                            E H +  +L    +N  + C GG  ++  C+       +     
Sbjct: 236  RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295

Query: 784  EASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAIS 843
            +         + RL G   P  GRVEV  A TW +VCD  + LHAA+V+CREL  G A  
Sbjct: 296  QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355

Query: 844  LSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS-----RYT 898
               G   G+G G     + +C G E  L  CP      + C HS++ GV C+       T
Sbjct: 356  ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415

Query: 899  DVRLVNGKSQCDGQVEINVLG----HWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKY 954
             +RL  G+SQ +G+VE+ + G     WG +C   W   +A V CRQL  G A       +
Sbjct: 416  RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW 475

Query: 955  IGERS--VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLA 1012
              +      V      C G E  LD C           HG  ++   TG+       C  
Sbjct: 476  YWDSGNITEVVMSGVRCTGTELSLDQC---------AHHGTHITCKRTGTRFTAGVICSE 526

Query: 1013 NVSDPYL-SAVPEGSALICLEDKRLRLV 1039
              SD  L SA+ + +A I  ED+ L ++
Sbjct: 527  TASDLLLHSALVQETAYI--EDRPLHML 552



 Score =  204 bits (520), Expect = 4e-52
 Identities = 149/505 (29%), Positives = 208/505 (41%), Gaps = 81/505 (16%)

Query: 257 SSDLELRLVGGTNRCM-GRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLP 315
           S  L  RL G   +   GRVE++  G WGT+C   +   AA ++C++LG   A  +    
Sbjct: 39  SQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSA 98

Query: 316 HLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDG----------- 364
               G+  +WLD +SCSG E  + +C   G  N DC H  D  VIC D            
Sbjct: 99  KYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVI 158

Query: 365 --------ADLELRLADGSNN-----CSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
                    ++ +R A G          G VEVR+ + W  +CD+ W    + VVC  LG
Sbjct: 159 EVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG 218

Query: 412 CPFSV---FGSRRAKPSNEARDIWINSISCTGNESALWDCT---YDGKAKRTCFRRSDAG 465
            P          R     +     ++ ++C G E+ L  C+   Y       C     A 
Sbjct: 219 FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAV 278

Query: 466 VIC------------------SDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWST 507
           V C                    + +  +RL G   P  GR+EV     WGTVC  +W  
Sbjct: 279 VSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDL 338

Query: 508 RNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVH 567
             A+VVC++LG G            +  G I L +V C G E ++W C H      +C H
Sbjct: 339 HAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSH 398

Query: 568 REDVIVTCS---GDATWGLRLVGGSNRCSGRLEVYFQG----RWGTVCDDGWNSKAAAVV 620
            +D  V C+     A   +RL GG ++  GR+EV   G    RWG +C D W +  A V 
Sbjct: 399 SQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVA 458

Query: 621 CSQLDCPSSIIGMGLGNASTGYGKIW-----------LDDVSCDGDESDLWSCRNSGWGN 669
           C QL         GLG A+ G  + W           +  V C G E  L  C + G  +
Sbjct: 459 CRQL---------GLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG-TH 508

Query: 670 NDCSHSE---DVGVICSD-ASDMEL 690
             C  +      GVICS+ ASD+ L
Sbjct: 509 ITCKRTGTRFTAGVICSETASDLLL 533



 Score =  195 bits (495), Expect = 3e-49
 Identities = 141/462 (30%), Positives = 200/462 (43%), Gaps = 79/462 (17%)

Query: 166 GRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNS----PAVLRPIWLDD 221
           GRVE++    WGTICDD + L  A ++CR+LG   +   +G  +S    P   R IWLD+
Sbjct: 56  GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEA---TGWTHSAKYGPGTGR-IWLDN 111

Query: 222 ILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS-------------------SDLEL 262
           + C G E ++  C  RGWGN DC+H+ED  + C D                     ++ +
Sbjct: 112 LSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRI 171

Query: 263 RLVGGTNR-----CMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT-----ALHFA 312
           R   G  R       G VE+++   W  VC   W+   + VVC  LG  +     A  + 
Sbjct: 172 RPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYR 231

Query: 313 GLPHLQSGSDVVWLDGVSCSGNESFLWDCR---HSGTVNFDCLHQNDVSVICSDG----- 364
            L   Q  S    L GV+C G E+ L  C    +       C       V C  G     
Sbjct: 232 LLAQRQQHS--FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAA 289

Query: 365 -------------ADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
                         +  +RL  G++   GRVEV     W T+CD+ W    A VVC++LG
Sbjct: 290 SSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELG 349

Query: 412 CPFSVFGSRR-----AKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGV 466
                FGS R     A+       I ++ + C+G E +LW C +       C    DAGV
Sbjct: 350 -----FGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGV 404

Query: 467 ICS---DKADLDLRLVGAHSPCYGRLEVKYQG----EWGTVCHDRWSTRNAAVVCKQLGC 519
            C+     A+  +RL G  S   GR+EV+  G     WG +C D W T  A V C+QLG 
Sbjct: 405 RCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGL 464

Query: 520 GKPMHVFGMTYFKEASG--PIWLDDVSCIGNESNIWDCEHSG 559
           G   H    T++ ++     + +  V C G E ++  C H G
Sbjct: 465 GYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG 506



 Score =  194 bits (494), Expect = 4e-49
 Identities = 133/447 (29%), Positives = 199/447 (44%), Gaps = 57/447 (12%)

Query: 380 GRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCT 439
           GRVE++   +W TICD ++  + A ++C++LG   +   +  AK       IW++++SC+
Sbjct: 56  GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 440 GNESALWDCTYDGKAKRTCFRRSDAGVICSDK-----ADLDLRLVGAHSPCY-------- 486
           G E ++ +C   G     C    DAGVIC D+     +D ++  V  H            
Sbjct: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 487 -----------GRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTY---FK 532
                      G +EV+    W  VC   WS  N+ VVC  LG      V    Y    +
Sbjct: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235

Query: 533 EASGPIWLDDVSCIGNESNIWDCEHSGWGKHN---CVHREDVIVTCSGDATWG------- 582
                  L  V+C+G E+++  C    +  ++   C      +V+C     +        
Sbjct: 236 RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295

Query: 583 -----------LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSII 631
                      +RL GG++   GR+EV     WGTVCD  W+  AA+VVC +L   S+  
Sbjct: 296 QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355

Query: 632 GMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS---DASDM 688
            +       G G I L +V C G E  LW C +      DCSHS+D GV C+     ++ 
Sbjct: 356 ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415

Query: 689 ELRLVGGSSRCAGKVEVNVQG----AVGILCANGWGMNIAEVVCRQLECGSAIRVSREPH 744
            +RL GG S+  G+VEV + G      G++C + WG   A V CRQL  G A    +E  
Sbjct: 416 RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW 475

Query: 745 FTE--RTLHILMSNSGCTGGEASLWDC 769
           + +      ++MS   CTG E SL  C
Sbjct: 476 YWDSGNITEVVMSGVRCTGTELSLDQC 502



 Score =  192 bits (488), Expect = 2e-48
 Identities = 133/463 (28%), Positives = 198/463 (42%), Gaps = 56/463 (12%)

Query: 803  PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862
            P  GRVE++ A  W ++CD DF+L AA++LCREL   +A   +    +G G G  W +  
Sbjct: 53   PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112

Query: 863  QCEGSETHLALCPIVQHPEDTCIHSREVGVVCS-----RYTDVRLVNGKSQ--------- 908
             C G+E  +  C         C H  + GV+C       ++D  ++  +           
Sbjct: 113  SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172

Query: 909  ------------CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKY-- 954
                         +G VE+ +   W  +CD  W   ++ V+C  L   +        Y  
Sbjct: 173  PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232

Query: 955  IGERSVRVWG-HRFHCLGNESLLDNCQMTVLGA---PPCIHGNTVSVICTGSLTQPLFPC 1010
            + +R    +G H   C+G E+ L  C +    A     C  G    V C   +  P++  
Sbjct: 233  LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC---VPGPVYAA 289

Query: 1011 LANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDA 1070
             +       S  P+G A       R+RL  G     GRVE+     WGT+CD  WDL  A
Sbjct: 290  SSGQKKQQQSK-PQGEA-------RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAA 341

Query: 1071 HVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKED 1130
             VVC++LG G A  A   A  G+G G I L ++ C+G E  LW+CP +     DC H +D
Sbjct: 342  SVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQD 401

Query: 1131 AGVICS-----EFTALRLYSETETESCAGRLEVFYNG----TWGSVGRRNITTAIAGIVC 1181
            AGV C+       T +RL          GR+EV   G     WG +   +  T  A + C
Sbjct: 402  AGVRCNLPYTGAETRIRLSGGRSQHE--GRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459

Query: 1182 RQLGCG--ENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQC 1222
            RQLG G   +G+             + +  ++C  T +S+ QC
Sbjct: 460  RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502



 Score =  160 bits (406), Expect = 6e-39
 Identities = 135/484 (27%), Positives = 193/484 (39%), Gaps = 60/484 (12%)

Query: 910  DGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHC 969
            +G+VEI   G WG++CD  +  + A +LCR+L    A   T     G  + R+W     C
Sbjct: 55   EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114

Query: 970  LGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALI 1029
             G E  +  C     G   C H     VIC           L   SD   S V E    +
Sbjct: 115  SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQR-------LPGFSD---SNVIEVEHHL 164

Query: 1030 CLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLG------ 1078
             +E+ R+R   G  R       G VE+     W  +CD GW   ++HVVC  LG      
Sbjct: 165  QVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKR 224

Query: 1079 CGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHD---CRHKEDAGVIC 1135
               AF   ++       G   L  + C G E+HL  C    +  +D   C     A V C
Sbjct: 225  VNAAFYRLLAQRQQHSFG---LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281

Query: 1136 --------SEFTALRLYSETETESCA----------GRLEVFYNGTWGSVGRRNITTAIA 1177
                    S     +  S+ + E+            GR+EV    TWG+V  R      A
Sbjct: 282  VPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAA 341

Query: 1178 GIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEE 1237
             +VCR+LG G             G G + + +++C    +S+W+C          S +++
Sbjct: 342  SVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQD 401

Query: 1238 TWITC-------EDRIRVRGGDTECSGRVEIWHAGS----WGTVCDDSWDLAEAEVVCQQ 1286
              + C       E RIR+ GG ++  GRVE+   G     WG +C D W   EA V C+Q
Sbjct: 402  AGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQ 461

Query: 1287 LGCGSALAALRDASFGQGTG--TIWLDDMRCKGNESFLWDC--HAKPWGQSDCGHKEDAG 1342
            LG G A   L++  +        + +  +RC G E  L  C  H         G +  AG
Sbjct: 462  LGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAG 521

Query: 1343 VRCS 1346
            V CS
Sbjct: 522  VICS 525



 Score =  155 bits (392), Expect = 3e-37
 Identities = 121/429 (28%), Positives = 171/429 (39%), Gaps = 64/429 (14%)

Query: 474 LDLRLVG-AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFK 532
           L  RL G    P  GR+E++  GEWGT+C D ++ + A ++C++LG  +         + 
Sbjct: 42  LRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYG 101

Query: 533 EASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLR-------- 584
             +G IWLD++SC G E ++ +C   GWG  +C H ED  V C      G          
Sbjct: 102 PGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVE 161

Query: 585 ------------LVGGSNR----CSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPS 628
                        VG   R      G +EV     W  VCD GW++  + VVC  L  PS
Sbjct: 162 HHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPS 221

Query: 629 ------SIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNND---CSHSEDVG 679
                 +   +        +G   L  V+C G E+ L  C    +  ND   C       
Sbjct: 222 EKRVNAAFYRLLAQRQQHSFG---LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAV 278

Query: 680 VIC------------------SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGM 721
           V C                      +  +RL GG+    G+VEV      G +C   W +
Sbjct: 279 VSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDL 338

Query: 722 NIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHL 781
           + A VVCR+L  GSA          +    I +S   C+G E SLW C         C  
Sbjct: 339 HAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSH 398

Query: 782 NMEASLICS-----AHRQPRLVGADMPCSGRVEVKHAD----TWRSVCDSDFSLHAANVL 832
           + +A + C+     A  + RL G      GRVEV+        W  +C  D+    A V 
Sbjct: 399 SQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVA 458

Query: 833 CRELNCGDA 841
           CR+L  G A
Sbjct: 459 CRQLGLGYA 467



 Score =  145 bits (367), Expect = 2e-34
 Identities = 130/500 (26%), Positives = 189/500 (37%), Gaps = 92/500 (18%)

Query: 701  GKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCT 760
            G+VE+   G  G +C + + +  A ++CR+L    A   +    +   T  I + N  C+
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 761  GGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADM------------------ 802
            G E S+ +C    W  + C  + +A +IC   R P    +++                  
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175

Query: 803  --------PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854
                       G VEV+  D W  VCD  +S H ++V+C  L  G      V   F +  
Sbjct: 176  GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLL 233

Query: 855  GLTWAEKF-----QCEGSETHLALCPI-VQHPEDT--CIHSREVGVVC------------ 894
                   F      C G+E HL+LC +      DT  C       V C            
Sbjct: 234  AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293

Query: 895  --------SRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946
                         VRL  G    +G+VE+     WG++CD  WD   A V+CR+L  G+A
Sbjct: 294  KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353

Query: 947  LSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006
                 G  +G+    +      C G E  L  C    + A  C H     V C       
Sbjct: 354  REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC------- 406

Query: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDG----FWGTICD 1062
                    + PY  A           + R+RL  G S+  GRVE+   G     WG IC 
Sbjct: 407  --------NLPYTGA-----------ETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447

Query: 1063 DGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSG--PIWLDDLNCTGMESHLWQCPSRGW 1120
            D W   +A V C++LG G A +      + +      + +  + CTG E  L QC   G 
Sbjct: 448  DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506

Query: 1121 GQHDCRH---KEDAGVICSE 1137
                C+    +  AGVICSE
Sbjct: 507  THITCKRTGTRFTAGVICSE 526



 Score =  122 bits (307), Expect = 2e-27
 Identities = 74/208 (35%), Positives = 103/208 (49%), Gaps = 19/208 (9%)

Query: 45  DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLG---CPFSFAMFRFG 101
           +  +RL  G  P  G VEV     WGTVCD  W+  A++VVC++LG      + +  R G
Sbjct: 304 EARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMG 363

Query: 102 QAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---YGEANLGLRLV 158
           Q +   G I L +V C G E +LW+C H+   + +C H +D GV C   Y  A   +RL 
Sbjct: 364 QGM---GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS 420

Query: 159 DGNNSCSGRVEVKF----QERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNS---- 210
            G +   GRVEV+       RWG IC D W    A V CRQLG    + + G+  +    
Sbjct: 421 GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGL--GYANHGLQETWYWD 478

Query: 211 PAVLRPIWLDDILCQGNELALWNCRHRG 238
              +  + +  + C G EL+L  C H G
Sbjct: 479 SGNITEVVMSGVRCTGTELSLDQCAHHG 506



 Score =  108 bits (269), Expect = 5e-23
 Identities = 47/101 (46%), Positives = 62/101 (61%)

Query: 1257 GRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCK 1316
            GRVEI  AG WGT+CDD + L  A ++C++LG   A      A +G GTG IWLD++ C 
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 1317 GNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASS 1357
            G E  + +C ++ WG SDC H EDAGV C  Q L   + S+
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN 156



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 16/105 (15%)

Query: 41  FNGTDLELRLVNGDGPCSGTVEVKFQG----QWGTVCDDGWNTTASTVVCKQLGCPFSFA 96
           + G +  +RL  G     G VEV+  G    +WG +C D W T  + V C+QLG  ++  
Sbjct: 410 YTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-- 467

Query: 97  MFRFGQAVTRH------GKIWLDDVSCYGNESALWECQHREWGSH 135
               G   T +       ++ +  V C G E +L +C H   G+H
Sbjct: 468 --NHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH--GTH 508


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  220 bits (561), Expect = 7e-57
 Identities = 152/504 (30%), Positives = 217/504 (43%), Gaps = 80/504 (15%)

Query: 47  ELRLVNGDG-PCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVT 105
           +LRLV  +  P  G +EV  QGQWGTVCDD +    +TV C+QLG   +       +   
Sbjct: 31  KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90

Query: 106 RHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCS 165
             G IWLD+V C G ES+L +C    WG  +C H EDVGV C+   + G      +N+  
Sbjct: 91  GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150

Query: 166 --------------------------GRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCP 199
                                     G VEVK++  W  +CD GW +N + VVC  LG P
Sbjct: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210

Query: 200 SSFI----------------SSGVVNSPAVLRPIWLDDILCQGNELALWNCR-----HRG 238
           S                       + S       W+  + C G E  + NC+      RG
Sbjct: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270

Query: 239 WGNHDCSHNEDVTLTCYD-----------------SSDLELRLVGGTNRCMGRVELKIQG 281
                C       ++C                   + +  +RL  G     GRVE+ +  
Sbjct: 271 KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330

Query: 282 RWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDC 341
           +WGTVC H+WN  +A VVC+QLG G+A        L  G   + L  V C G E  L DC
Sbjct: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390

Query: 342 RHSGTVNFDCLHQNDVSVIC---SDGADLELRLADGSNNCSGRVEVRIH----EQWWTIC 394
                    C H+ND +V C   + G   ++RLA G     G +EV++      +W ++C
Sbjct: 391 PALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVC 450

Query: 395 DQNWKNEQALVVCKQLGCPFSVFGSRRA---KPSNEARDIWINSISCTGNESALWDCTYD 451
            +NW   +A+V C+QLG  F++   +       +  A+++ ++ + C+G E AL  C   
Sbjct: 451 SENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH 510

Query: 452 GKAKRTCFR---RSDAGVICSDKA 472
           G     C     R  AGV C D A
Sbjct: 511 GPVH--CSHGGGRFLAGVSCMDSA 532



 Score =  201 bits (511), Expect = 4e-51
 Identities = 130/381 (34%), Positives = 170/381 (44%), Gaps = 69/381 (18%)

Query: 1035 RLRLVDGDSRCA-GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGE 1093
            +LRLV  +S+   GR+E+ H G WGT+CDD + + +A V C++LG   A     SA +G+
Sbjct: 31   KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90

Query: 1094 GSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLYSETETESCA 1153
            G GPIWLD++ C G ES L QC S GWG  DC H ED GVIC         SET + +  
Sbjct: 91   GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150

Query: 1154 --------------------------GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187
                                      G +EV Y G W  V  +  T   + +VC  LG  
Sbjct: 151  PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210

Query: 1188 ENGVVSLAPLSK----------------TGSGFMWVDDIQCPKT--HISIWQCLSAPWER 1229
                V      K                T     W+  + C  T  H++  Q   AP   
Sbjct: 211  SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270

Query: 1230 RI------------------------SSPAEETWITCEDRIRVRGGDTECSGRVEIWHAG 1265
            ++                        + P  +     E R+R+R G     GRVE+    
Sbjct: 271  KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330

Query: 1266 SWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDC 1325
             WGTVCD  W+L  A VVC+QLG GSA  AL  A  GQG G I L ++RC+G E  L DC
Sbjct: 331  QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390

Query: 1326 HAKPWGQSDCGHKEDAGVRCS 1346
             A    Q+ C H+ DA VRC+
Sbjct: 391  PALEGSQNGCQHENDAAVRCN 411



 Score =  195 bits (495), Expect = 3e-49
 Identities = 156/493 (31%), Positives = 216/493 (43%), Gaps = 83/493 (16%)

Query: 580 TWGLRLVGGSNRCS-GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA 638
           T  LRLVG  ++   GRLEV  QG+WGTVCDD +  + A V C QL   +++        
Sbjct: 29  TTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKY 88

Query: 639 STGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC-------------SDA 685
             G G IWLD+V C G ES L  C ++GWG +DCSHSEDVGVIC             S+A
Sbjct: 89  GQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNA 148

Query: 686 --------SDMELRLVGGSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLE 732
                    ++ L+ +  S++       G VEV  +G    +C  GW MN + VVC  L 
Sbjct: 149 LGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLG 208

Query: 733 CGSAIRVS------------REPHFTERTL----HILMSNSGCTGGEASLWDC------I 770
             S + V             R+P    ++L       +    C G E  + +C       
Sbjct: 209 FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPA 268

Query: 771 RWEWKQTACHLNMEASLICSA--HRQP-----------------RLVGADMPCSGRVEVK 811
           R + +  AC   M A + C A  H +P                 RL        GRVEV 
Sbjct: 269 RGKLR-PACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVL 327

Query: 812 HADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHL 871
               W +VCD  ++L +A+V+CR+L  G A     G   G+G G     + +C G E  L
Sbjct: 328 MNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTL 387

Query: 872 ALCPIVQHPEDTCIHSREVGVVCS-----RYTDVRLVNGKSQCDG----QVEINVLGHWG 922
           + CP ++  ++ C H  +  V C+         VRL  G+   +G    QVE+N +  WG
Sbjct: 388 SDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWG 447

Query: 923 SLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGE---RSVRVWGHRFHCLGNESLLDNC 979
           S+C  +W   +A V CRQL  G A+      +      R+  V      C G E  L  C
Sbjct: 448 SVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507

Query: 980 QMTVLGAPPCIHG 992
           Q    G   C HG
Sbjct: 508 QRH--GPVHCSHG 518



 Score =  192 bits (489), Expect = 2e-48
 Identities = 146/491 (29%), Positives = 211/491 (42%), Gaps = 80/491 (16%)

Query: 796  RLVGADM-PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854
            RLVG +  P  GR+EV H   W +VCD +F++  A V CR+L    A++ +    +G+G 
Sbjct: 33   RLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGE 92

Query: 855  GLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS------------------- 895
            G  W +  +C G+E+ L  C         C HS +VGV+C                    
Sbjct: 93   GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQ 152

Query: 896  --RYTDVRL----VNGKSQC---DGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946
              R  +VRL     + K      +G VE+   GHW  +CD  W   ++RV+C  L   + 
Sbjct: 153  GRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSE 212

Query: 947  LSTTGGKY--IGERSVR--------------VWGHRFHCLGNESLLDNCQMTVLGA---- 986
            +      Y  + +  +R               W H+  CLG E  + NCQ+ V  A    
Sbjct: 213  VPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKL 272

Query: 987  -PPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRC 1045
             P C  G    V C             +   P      +GS     E+ R+RL  G    
Sbjct: 273  RPACPGGMHAVVSCVAG---------PHFRPPKTKPQRKGS---WAEEPRVRLRSGAQVG 320

Query: 1046 AGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNC 1105
             GRVE+  +  WGT+CD  W+L  A VVC++LG G A  A   A  G+G GPI L ++ C
Sbjct: 321  EGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRC 380

Query: 1106 TGMESHLWQCPSRGWGQHDCRHKEDAGVICSE-----FTALRLYSETETESCAGRLEVFY 1160
             G E  L  CP+    Q+ C+H+ DA V C+         +RL      E     ++V  
Sbjct: 381  RGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEV 440

Query: 1161 NGT--WGSVGRRNITTAIAGIVCRQLGCG-------ENGVVSLAPLSKTGSGFMWVDDIQ 1211
            NG   WGSV   N     A + CRQLG G       E    S  P ++     + +  ++
Sbjct: 441  NGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQE----VVMSGVR 496

Query: 1212 CPKTHISIWQC 1222
            C  T +++ QC
Sbjct: 497  CSGTELALQQC 507



 Score =  189 bits (480), Expect = 2e-47
 Identities = 156/513 (30%), Positives = 200/513 (38%), Gaps = 98/513 (19%)

Query: 261 ELRLVGGTNRCM-GRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQS 319
           +LRLVG  ++   GR+E+  QG+WGTVC   +    A V C+QLG   AL +A       
Sbjct: 31  KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90

Query: 320 GSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS----------------- 362
           G   +WLD V C G ES L  C  +G    DC H  DV VIC                  
Sbjct: 91  GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150

Query: 363 -DGADLE-LRLA-------DGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCP 413
             G  LE +RL          S    G VEV+    W  +CDQ W    + VVC  LG P
Sbjct: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210

Query: 414 FSV----------------FGSRRAKPSNEARDIWINSISCTGNESALWDCTYD-----G 452
             V                    R K        WI+ ++C G E  + +C        G
Sbjct: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270

Query: 453 KAKRTCFRRSDAGVIC-----------------SDKADLDLRLVGAHSPCYGRLEVKYQG 495
           K +  C     A V C                 S   +  +RL        GR+EV    
Sbjct: 271 KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330

Query: 496 EWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDC 555
           +WGTVC  RW+  +A+VVC+QLG G            +  GPI L +V C G E  + DC
Sbjct: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390

Query: 556 EHSGWGKHNCVHREDVIVTCSGDATW---GLRLVGGSNRCSGRLEVYFQ----GRWGTVC 608
                 ++ C H  D  V C+         +RL GG     G LEV  +     RWG+VC
Sbjct: 391 PALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVC 450

Query: 609 DDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW------------LDDVSCDGDE 656
            + W    A V C QL         GLG A   Y + W            +  V C G E
Sbjct: 451 SENWGLTEAMVACRQL---------GLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTE 501

Query: 657 SDLWSCRNSGWGNNDCSHSED---VGVICSDAS 686
             L  C+    G   CSH       GV C D++
Sbjct: 502 LALQQCQRH--GPVHCSHGGGRFLAGVSCMDSA 532



 Score =  167 bits (423), Expect = 7e-41
 Identities = 137/518 (26%), Positives = 213/518 (41%), Gaps = 89/518 (17%)

Query: 898  TDVRLVNGKSQCD-GQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            T +RLV  +S+ + G++E+   G WG++CD ++  ++A V CRQL    AL+       G
Sbjct: 30   TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89

Query: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVIC-----TGSLTQPLFPCL 1011
            +    +W     C+G ES LD C     G   C H   V VIC      G L++ +   L
Sbjct: 90   QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149

Query: 1012 ANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWD 1066
                       P+G  L   E+ RL+ +   ++       G VE+ ++G W  +CD GW 
Sbjct: 150  G----------PQGRRL---EEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196

Query: 1067 LSDAHVVCQKLGCGVAFNATVSAHFGE------------------GSGPIWLDDLNCTGM 1108
            ++++ VVC  LG        V +H+                         W+  + C G 
Sbjct: 197  MNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254

Query: 1109 ESHLWQC-----PSRGWGQHDCRHKEDAGVIC-------------------SEFTALRLY 1144
            E H+  C     P+RG  +  C     A V C                   +E   +RL 
Sbjct: 255  EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLR 314

Query: 1145 SETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGF 1204
            S  +     GR+EV  N  WG+V         A +VCRQLG G             G G 
Sbjct: 315  SGAQVGE--GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGP 372

Query: 1205 MWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITC-------EDRIRVRGGDTECSG 1257
            + + +++C     ++  C +    +       +  + C       ++++R+ GG     G
Sbjct: 373  IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEG 432

Query: 1258 ----RVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGT---GTIWL 1310
                +VE+     WG+VC ++W L EA V C+QLG G A+ A ++  F  GT     + +
Sbjct: 433  LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVM 492

Query: 1311 DDMRCKGNESFLWDCHAKPWGQSDCGH---KEDAGVRC 1345
              +RC G E  L  C     G   C H   +  AGV C
Sbjct: 493  SGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSC 528


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  206 bits (525), Expect = 1e-52
 Identities = 154/486 (31%), Positives = 209/486 (43%), Gaps = 95/486 (19%)

Query: 260 LELRLVGGTNR-CMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQ 318
           ++LRL G   +   GRVE+   G+WGTVC   ++  AA VVC++LG   A  +       
Sbjct: 56  IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG 115

Query: 319 SGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSD----GADLELRLADG 374
            G   +WLD + C+GNE+ L  C  +G    DC H  DV V+CSD    G   +  L + 
Sbjct: 116 KGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQ 175

Query: 375 SNNCS-----------------------GRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
             N +                       G VEV+  + W  ICD++W  + + VVC   G
Sbjct: 176 IENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG 235

Query: 412 CP---------FSVFGSRRAKPSNEARDIWINSISCTGNESALWDC------TYDGKAKR 456
            P         + +F SRR       +  W  S+ CTG E+ +  C      + D     
Sbjct: 236 FPGERTYNTKVYKMFASRR------KQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNV 289

Query: 457 TCFRRSDAGVIC----------------SDKADLDL-RLVGAHSPCYGRLEVKYQGEWGT 499
           TC     A V C                + K +  L RL G      GR+EV   GEWGT
Sbjct: 290 TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGT 349

Query: 500 VCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSG 559
           VC D+W   +A+VVC++LG G        +   +  GPI L+++ C GNE +I DC+ + 
Sbjct: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409

Query: 560 WGKHNCVHREDVIVTCSGDATW---GLRLVGGSNRCSGRLEVYFQGR----WGTVCDDGW 612
                C H ED  V C+  A      LRL GG N   GR+EV  +      WG VC   W
Sbjct: 410 -ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468

Query: 613 NSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW------------LDDVSCDGDESDLW 660
               A VVC QL         GLG AS  + + W            +  V C G E  L 
Sbjct: 469 GIVEAMVVCRQL---------GLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLA 519

Query: 661 SCRNSG 666
            CR+ G
Sbjct: 520 HCRHDG 525



 Score =  206 bits (525), Expect = 1e-52
 Identities = 131/377 (34%), Positives = 180/377 (47%), Gaps = 71/377 (18%)

Query: 1047 GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCT 1106
            GRVE+Y+DG WGT+CDD + +  AHVVC++LG   A + T S+ +G+G GPIWLD+L+CT
Sbjct: 70   GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 1107 GMESHLWQCPSRGWGQHDCRHKEDAGVICSE---------------------------FT 1139
            G E+ L  C S GWG  DC+H ED GV+CS+                             
Sbjct: 130  GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRIR 189

Query: 1140 ALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC-GE---NGVVSLA 1195
            A+       T    G +EV    TW  +  ++ T   + +VC   G  GE   N  V   
Sbjct: 190  AILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKM 249

Query: 1196 PLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDR---------- 1245
              S+    + W   + C  T   I  C   P   ++S    +  +TCE+           
Sbjct: 250  FASRRKQRY-WPFSMDCTGTEAHISSCKLGP---QVSLDPMKN-VTCENGLPAVVSCVPG 304

Query: 1246 ---------------------IRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVC 1284
                                 +R+RGG     GRVE+   G WGTVCDD WDL  A VVC
Sbjct: 305  QVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVC 364

Query: 1285 QQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVR 1344
            ++LG GSA  A+  +  GQG G I L++++C GNE  + DC      Q  C H+EDAGVR
Sbjct: 365  RELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG-CNHEEDAGVR 423

Query: 1345 CSGQSL---KSLNASSG 1358
            C+  ++   K L  + G
Sbjct: 424  CNTPAMGLQKKLRLNGG 440



 Score =  203 bits (517), Expect = 9e-52
 Identities = 153/506 (30%), Positives = 216/506 (42%), Gaps = 85/506 (16%)

Query: 42  NGTDLELRLVNGDGPCS-GTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRF 100
           N   ++LRL       S G VEV + GQWGTVCDD ++  A+ VVC++LG   + +    
Sbjct: 52  NVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTAS 111

Query: 101 GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEA--------- 151
                  G IWLD++ C GNE+ L  C    WG  +C H EDVGV C  +          
Sbjct: 112 SSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS 171

Query: 152 ------NLGLRLVD------------GNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVC 193
                 NL +++ D                  G VEVK  + W  ICD  W    + VVC
Sbjct: 172 LINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC 231

Query: 194 RQLGCPSSFISSGVVNSPAVLRP---IWLDDILCQGNELALWNCRHRGWGNHD------C 244
              G P     +  V      R     W   + C G E  + +C+     + D      C
Sbjct: 232 GMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTC 291

Query: 245 SHNEDVTLTC-----------------YDSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287
            +     ++C                 Y      +RL GG     GRVE+   G WGTVC
Sbjct: 292 ENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVC 351

Query: 288 HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347
             KW+  +A VVC++LG G+A        L  G   + L+ + C+GNE  + DC+ +   
Sbjct: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAES 411

Query: 348 NFDCLHQNDVSVICSD---GADLELRLADGSNNCSGRVEVRIHEQ----WWTICDQNWKN 400
              C H+ D  V C+    G   +LRL  G N   GRVEV +       W  +C QNW  
Sbjct: 412 Q-GCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGI 470

Query: 401 EQALVVCKQLGCPFSVFGSRRAKPSNEARDIW------------INSISCTGNESALWDC 448
            +A+VVC+QLG  F+         SN  ++ W            ++ + C+G E +L  C
Sbjct: 471 VEAMVVCRQLGLGFA---------SNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521

Query: 449 TYDGK--AKRTCFRRSDAGVICSDKA 472
            +DG+  A      +  AGV CS+ A
Sbjct: 522 RHDGEDVACPQGGVQYGAGVACSETA 547



 Score =  196 bits (498), Expect = 1e-49
 Identities = 147/489 (30%), Positives = 206/489 (42%), Gaps = 74/489 (15%)

Query: 138 YHGEDVGVNCYGEANLGLRLVDGNNSCS-GRVEVKFQERWGTICDDGWNLNTAAVVCRQL 196
           YH      N    A + LRL       S GRVEV +  +WGT+CDD ++++ A VVCR+L
Sbjct: 44  YHQPQAPANV---AKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCREL 100

Query: 197 GCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYD 256
           G   +   +   +      PIWLD++ C GNE  L  C   GWG  DC H EDV + C D
Sbjct: 101 GYVEAKSWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSD 160

Query: 257 S----------------------SDLELRLVGGTNR-----CMGRVELKIQGRWGTVCHH 289
                                   D+ +R +  T R       G VE+K    W  +C  
Sbjct: 161 KRIPGFKFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDK 220

Query: 290 KWNNAAADVVCKQLGCGTALHFAGLPHLQSGS---DVVWLDGVSCSGNESFLWDCRHSGT 346
            W    + VVC   G      +    +    S      W   + C+G E+ +  C+    
Sbjct: 221 HWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQ 280

Query: 347 VNFD------CLHQNDVSVICSDGADLE-----------------LRLADGSNNCSGRVE 383
           V+ D      C +     V C  G                     +RL  G+    GRVE
Sbjct: 281 VSLDPMKNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVE 340

Query: 384 VRIHEQWWTICDQNWKNEQALVVCKQLG---CPFSVFGSRRAKPSNEARDIWINSISCTG 440
           V  + +W T+CD  W    A VVC++LG      +V GSR  +       I +N I CTG
Sbjct: 341 VLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIG---PIHLNEIQCTG 397

Query: 441 NESALWDCTYDGKAKRTCFRRSDAGVICSDKA---DLDLRLVGAHSPCYGRLEVKYQGE- 496
           NE ++ DC ++ ++ + C    DAGV C+  A      LRL G  +P  GR+EV  +   
Sbjct: 398 NEKSIIDCKFNAES-QGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNG 456

Query: 497 ---WGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEA---SGPIWLDDVSCIGNES 550
              WG VC   W    A VVC+QLG G   + F  T++      S  + +  V C G E 
Sbjct: 457 SLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTEL 516

Query: 551 NIWDCEHSG 559
           ++  C H G
Sbjct: 517 SLAHCRHDG 525



 Score =  195 bits (495), Expect = 3e-49
 Identities = 141/435 (32%), Positives = 192/435 (44%), Gaps = 49/435 (11%)

Query: 794  QPRLVGADMPCS-GRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGK 852
            Q RL G     S GRVEV +   W +VCD DFS+HAA+V+CREL   +A S +    +GK
Sbjct: 57   QLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116

Query: 853  GNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS----------------- 895
            G G  W +   C G+E  LA C         C H+ +VGVVCS                 
Sbjct: 117  GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176

Query: 896  -----RYTDVRLVNGKSQ-------CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSC 943
                 +  D+R+    S         +G VE+     W  +CD HW  +++RV+C     
Sbjct: 177  ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236

Query: 944  G---TALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
                T  +     +   R  R W     C G E+ + +C++     P        +V C 
Sbjct: 237  PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKL----GPQVSLDPMKNVTCE 292

Query: 1001 GSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTI 1060
              L   +      V  P              E   +RL  G     GRVE+  +G WGT+
Sbjct: 293  NGLPAVVSCVPGQVFSP--DGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTV 350

Query: 1061 CDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGW 1120
            CDD WDL  A VVC++LG G A  A   +  G+G GPI L+++ CTG E  +  C     
Sbjct: 351  CDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE 410

Query: 1121 GQHDCRHKEDAGVICSEFTALRLYSETETES----CAGRLEVFY--NGT--WGSVGRRNI 1172
             Q  C H+EDAGV C+   A+ L  +           GR+EV    NG+  WG V  +N 
Sbjct: 411  SQ-GCNHEEDAGVRCNT-PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468

Query: 1173 TTAIAGIVCRQLGCG 1187
                A +VCRQLG G
Sbjct: 469  GIVEAMVVCRQLGLG 483



 Score =  173 bits (438), Expect = 1e-42
 Identities = 137/466 (29%), Positives = 198/466 (42%), Gaps = 69/466 (14%)

Query: 583 LRLVGGSNRCS-GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTG 641
           LRL G   + S GR+EVY+ G+WGTVCDD ++  AA VVC +L    +       +   G
Sbjct: 58  LRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKG 117

Query: 642 YGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSD----------------- 684
            G IWLD++ C G+E+ L +C ++GWG  DC H+EDVGV+CSD                 
Sbjct: 118 EGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIE 177

Query: 685 -----ASDMELRLVGGSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECG 734
                  D+ +R +  + R       G VEV        +C   W    + VVC      
Sbjct: 178 NLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237

Query: 735 SAIRVSREPH---FTERTLHILMSNSGCTGGEASLWDCIRW------EWKQTACHLNMEA 785
                + + +    + R       +  CTG EA +  C           K   C   + A
Sbjct: 238 GERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297

Query: 786 SLIC---------------SAHR--QP--RLVGADMPCSGRVEVKHADTWRSVCDSDFSL 826
            + C                A++  QP  RL G      GRVEV     W +VCD  + L
Sbjct: 298 VVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDL 357

Query: 827 HAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIH 886
            +A+V+CREL  G A     G   G+G G     + QC G+E  +  C      +  C H
Sbjct: 358 VSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAESQG-CNH 416

Query: 887 SREVGVVCSR-----YTDVRLVNGKSQCDGQVEINVLGH----WGSLCDTHWDPEDARVL 937
             + GV C+         +RL  G++  +G+VE+ V  +    WG +C  +W   +A V+
Sbjct: 417 EEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVV 476

Query: 938 CRQLSCG---TALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQ 980
           CRQL  G    A   T   +    S +V      C G E  L +C+
Sbjct: 477 CRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCR 522



 Score =  160 bits (405), Expect = 8e-39
 Identities = 134/474 (28%), Positives = 196/474 (41%), Gaps = 77/474 (16%)

Query: 472 ADLDLRLVGA---HSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGM 528
           A + LRL G    HS   GR+EV Y G+WGTVC D +S   A VVC++LG  +       
Sbjct: 54  AKIQLRLAGQKRKHSE--GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTAS 111

Query: 529 TYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWG------ 582
           + + +  GPIWLD++ C GNE+ +  C  +GWG  +C H EDV V CS     G      
Sbjct: 112 SSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNS 171

Query: 583 ----------------LRLVGGSNR-----CSGRLEVYFQGRWGTVCDDGWNSKAAAVVC 621
                           +R +  + R       G +EV     W  +CD  W +K + VVC
Sbjct: 172 LINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVC 231

Query: 622 SQLDCP------SSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCR------NSGWGN 669
                P      + +  M    AS    + W   + C G E+ + SC+           N
Sbjct: 232 GMFGFPGERTYNTKVYKM---FASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKN 288

Query: 670 NDCSHSEDVGVICSDASDME-----------------LRLVGGSSRCAGKVEVNVQGAVG 712
             C +     V C                        +RL GG+    G+VEV   G  G
Sbjct: 289 VTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWG 348

Query: 713 ILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRW 772
            +C + W +  A VVCR+L  GSA          +    I ++   CTG E S+ DC ++
Sbjct: 349 TVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC-KF 407

Query: 773 EWKQTACHLNMEASLICSA-----HRQPRLVGADMPCSGRVEV----KHADTWRSVCDSD 823
             +   C+   +A + C+       ++ RL G   P  GRVEV      +  W  VC  +
Sbjct: 408 NAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQN 467

Query: 824 FSLHAANVLCRELNCGDAISLSVGDHFGKG---NGLTWAEKFQCEGSETHLALC 874
           + +  A V+CR+L  G A +      +  G   +        +C G+E  LA C
Sbjct: 468 WGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHC 521



 Score =  147 bits (372), Expect = 6e-35
 Identities = 136/494 (27%), Positives = 197/494 (39%), Gaps = 67/494 (13%)

Query: 906  KSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGH 965
            +   +G+VE+   G WG++CD  +    A V+CR+L    A S T     G+    +W  
Sbjct: 65   RKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLD 124

Query: 966  RFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEG 1025
              HC GNE+ L  C     G   C H   V V+C+     P F       +  ++ +   
Sbjct: 125  NLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI-PGF----KFDNSLINQIENL 179

Query: 1026 SALICLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080
            +  I +ED R+R +    R       G VE+     W  ICD  W   ++ VVC   G  
Sbjct: 180  N--IQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFP 237

Query: 1081 V--AFNATVSAHFGEGSGP-IWLDDLNCTGMESHLWQCPSRGWGQHD------CRHKEDA 1131
                +N  V   F        W   ++CTG E+H+  C        D      C +   A
Sbjct: 238  GERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297

Query: 1132 GVIC-------------------SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNI 1172
             V C                    E   +RL          GR+EV  NG WG+V     
Sbjct: 298  VVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGE--GRVEVLKNGEWGTVCDDKW 355

Query: 1173 TTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRIS 1232
                A +VCR+LG G             G G + +++IQC     SI  C     E +  
Sbjct: 356  DLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQGC 414

Query: 1233 SPAEETWITC-------EDRIRVRGGDTECSGRVEIW--HAGS--WGTVCDDSWDLAEAE 1281
            +  E+  + C       + ++R+ GG     GRVE+     GS  WG VC  +W + EA 
Sbjct: 415  NHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAM 474

Query: 1282 VVCQQLGCGSALAALRDASFGQG---TGTIWLDDMRCKGNESFLWDCH------AKPWGQ 1332
            VVC+QLG G A  A ++  +  G   +  + +  ++C G E  L  C       A P G 
Sbjct: 475  VVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQG- 533

Query: 1333 SDCGHKEDAGVRCS 1346
               G +  AGV CS
Sbjct: 534  ---GVQYGAGVACS 544



 Score =  139 bits (349), Expect = 3e-32
 Identities = 129/528 (24%), Positives = 203/528 (38%), Gaps = 106/528 (20%)

Query: 683  SDASDMELRLVGGSSRCA-GKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR 741
            ++ + ++LRL G   + + G+VEV   G  G +C + + ++ A VVCR+L    A   + 
Sbjct: 51   ANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTA 110

Query: 742  EPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRL---- 797
               + +    I + N  CTG EA+L  C    W  T C    +  ++CS  R P      
Sbjct: 111  SSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDN 170

Query: 798  -----------------VGADMPC--------SGRVEVKHADTWRSVCDSDFSLHAANVL 832
                             + A +           G VEVK   TW+ +CD  ++   + V+
Sbjct: 171  SLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVV 230

Query: 833  CRELNCGDAISLSVGDH---FGKGNGLTWAEKFQCEGSETHLALCPIVQH------PEDT 883
            C         + +   +     +     W     C G+E H++ C +            T
Sbjct: 231  CGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMKNVT 290

Query: 884  CIHSREVGVVC-----------SRYTD--------VRLVNGKSQCDGQVEINVLGHWGSL 924
            C +     V C           SR+          VRL  G    +G+VE+   G WG++
Sbjct: 291  CENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTV 350

Query: 925  CDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVL 984
            CD  WD   A V+CR+L  G+A     G  +G+    +  +   C GNE  + +C+    
Sbjct: 351  CDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA- 409

Query: 985  GAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR 1044
             +  C H     V C               + P +              K+LRL  G + 
Sbjct: 410  ESQGCNHEEDAGVRC---------------NTPAMGL-----------QKKLRLNGGRNP 443

Query: 1045 CAGRVEIYHDG----FWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEG---SGP 1097
              GRVE+  +      WG +C   W + +A VVC++LG G A NA     +  G   S  
Sbjct: 444  YEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNK 503

Query: 1098 IWLDDLNCTGMESHLWQCPSRGWGQHDCRH--------KEDAGVICSE 1137
            + +  + C+G E  L  C      +HD           +  AGV CSE
Sbjct: 504  VVMSGVKCSGTELSLAHC------RHDGEDVACPQGGVQYGAGVACSE 545



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 52/223 (23%), Positives = 81/223 (36%), Gaps = 35/223 (15%)

Query: 1141 LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT 1200
            LRL  +    S  GR+EV+Y+G WG+V   + +   A +VCR+LG  E    + +     
Sbjct: 58   LRLAGQKRKHS-EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGK 116

Query: 1201 GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDR--------------- 1245
            G G +W+D++ C     ++  C S  W        E+  + C D+               
Sbjct: 117  GEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQI 176

Query: 1246 ---------IRVRG-------GDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGC 1289
                     IR+R              G VE+    +W  +CD  W    + VVC   G 
Sbjct: 177  ENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF 236

Query: 1290 GSAL---AALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKP 1329
                     +      +     W   M C G E+ +  C   P
Sbjct: 237  PGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGP 279


>gi|194018748 CD6 molecule [Homo sapiens]
          Length = 668

 Score =  199 bits (506), Expect = 2e-50
 Identities = 111/288 (38%), Positives = 153/288 (53%), Gaps = 23/288 (7%)

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959
            VRL NG S C G VE+ +   W   C   WD   A  +CR L CG A + +    +   +
Sbjct: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAAS---QLAPPT 101

Query: 960  VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYL 1019
              +        GN S+  N   T+ GAP        +++C+G+  +     L  V +   
Sbjct: 102  PELPPPP--AAGNTSVAANA--TLAGAP--------ALLCSGAEWR-----LCEVVEHAC 144

Query: 1020 SAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGC 1079
             +    + + C E++ LRLVDG   CAGRVE+   G WG++CDD WDL DAHVVC++LGC
Sbjct: 145  RSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGC 204

Query: 1080 GVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFT 1139
            G A  A    HF  G GPI  D +NC+G E++LW CP    GQH C HKEDAG +CSE  
Sbjct: 205  GWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQ 263

Query: 1140 ALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187
            + RL      + C G++EV + G W +V       + A ++C+ LGCG
Sbjct: 264  SWRLTG--GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309



 Score =  197 bits (502), Expect = 5e-50
 Identities = 123/343 (35%), Positives = 172/343 (50%), Gaps = 32/343 (9%)

Query: 358 SVICSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVF 417
           S +   G  L +RL +GS++CSG VEVR+   W   C   W +  A  VC+ LGC  +  
Sbjct: 34  SELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEA 93

Query: 418 GSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFR-------------RSD- 463
            S+ A P+ E     +      GN S   + T  G     C               RSD 
Sbjct: 94  ASQLAPPTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG 148

Query: 464 --AGVICSDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGK 521
             A V C++   L  RLV     C GR+E+   GEWG+VC D W   +A VVC+QLGCG 
Sbjct: 149 RRARVTCAENRAL--RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206

Query: 522 PMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATW 581
            +      +F    GPI  D V+C G E+ +WDC     G+H C H+ED    CS   +W
Sbjct: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSW 265

Query: 582 GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSI-IGMGLGNAST 640
             RL GG++RC G++EV+F+G W TVCD  W    A V+C  L C +++    GL ++ +
Sbjct: 266 --RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLS 323

Query: 641 GYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
             G+++    SC+G+E  L +C      +N CS S    V+CS
Sbjct: 324 --GRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361



 Score =  184 bits (468), Expect = 4e-46
 Identities = 121/342 (35%), Positives = 155/342 (45%), Gaps = 32/342 (9%)

Query: 43  GTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQ 102
           G  L +RL NG   CSGTVEV+ +  W   C   W++ A+  VC+ LGC  + A  +   
Sbjct: 40  GERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAP 99

Query: 103 AVTRHGKIWLDDVSCYGNESALWE----------CQHREWG-----SHNCYH-GEDVGVN 146
                    L      GN S              C   EW       H C   G    V 
Sbjct: 100 PTPE-----LPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVT 154

Query: 147 CYGEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSG 206
           C    N  LRLVDG  +C+GRVE+     WG++CDD W+L  A VVCRQLGC  +  +  
Sbjct: 155 C--AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALP 212

Query: 207 VVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRLVG 266
            ++      PI  D + C G E  LW+C     G H C H ED    C  S     RL G
Sbjct: 213 GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVC--SEHQSWRLTG 269

Query: 267 GTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHF-AGLPHLQSGSDVVW 325
           G +RC G+VE+  +G W TVC  +W  + A V+C+ LGCGTA+    GLPH  SG     
Sbjct: 270 GADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY-- 327

Query: 326 LDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADL 367
               SC+G E  L +C      +  C       V+CS    L
Sbjct: 328 ---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366



 Score =  181 bits (460), Expect = 3e-45
 Identities = 120/368 (32%), Positives = 173/368 (47%), Gaps = 31/368 (8%)

Query: 688  MELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR------ 741
            + +RL  GSS C+G VEV ++ +    C   W    AE VCR L CG A   S+      
Sbjct: 43   LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102

Query: 742  ---EPHFTERTLHILMSNSGCTGGEASLWDCIRW---EWKQTACHLN-MEASLICSAHRQ 794
                P     T   + +N+   G  A L     W   E  + AC  +   A + C+ +R 
Sbjct: 103  ELPPPPAAGNTS--VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRA 160

Query: 795  PRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854
             RLV     C+GRVE+     W SVCD  + L  A+V+CR+L CG A+    G HF  G 
Sbjct: 161  LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGR 220

Query: 855  GLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVE 914
            G    ++  C G+E +L  CP +   +  C H  + G VCS +   RL  G  +C+GQVE
Sbjct: 221  GPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVE 279

Query: 915  INVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNES 974
            ++  G W ++CD+ W P +A+VLC+ L CGTA+    G      S R++   + C G E 
Sbjct: 280  VHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKG-LPHSLSGRMY---YSCNGEEL 335

Query: 975  LLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSA-----VPEGSALI 1029
             L NC      +  C       V+C+ S +      L N+S P + A       E S  +
Sbjct: 336  TLSNCSWRFNNSNLCSQSLAARVLCSASRS------LHNLSTPEVPASVQTVTIESSVTV 389

Query: 1030 CLEDKRLR 1037
             +E+K  R
Sbjct: 390  KIENKESR 397



 Score =  173 bits (439), Expect = 9e-43
 Identities = 111/338 (32%), Positives = 154/338 (45%), Gaps = 30/338 (8%)

Query: 153 LGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPA 212
           L +RL +G++SCSG VEV+ +  W   C   W+   A  VCR LGC  +  +S +     
Sbjct: 43  LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTP 102

Query: 213 VLRP---------------IWLDDILCQGNELALWNCRHRGWGNHDC-SHNEDVTLTCYD 256
            L P                    +LC G E  L          H C S      +TC +
Sbjct: 103 ELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVE-----HACRSDGRRARVTCAE 157

Query: 257 SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPH 316
           +    LRLV G   C GRVE+   G WG+VC   W+   A VVC+QLGCG A+      H
Sbjct: 158 NR--ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH 215

Query: 317 LQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDGADLELRLADGSN 376
              G   +  D V+CSG E++LWDC      ++ C H+ D   +CS+      RL  G++
Sbjct: 216 FTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHY-CGHKEDAGAVCSE--HQSWRLTGGAD 272

Query: 377 NCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSI 436
            C G+VEV     W T+CD  W   +A V+C+ LGC  +V   +    S   R  +    
Sbjct: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY---- 328

Query: 437 SCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADL 474
           SC G E  L +C++       C +   A V+CS    L
Sbjct: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL 366



 Score =  152 bits (384), Expect = 2e-36
 Identities = 112/368 (30%), Positives = 153/368 (41%), Gaps = 55/368 (14%)

Query: 796  RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLS---------- 845
            RL      CSG VEV+   +W   C + +   AA  +CR L CG A + S          
Sbjct: 46   RLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELP 105

Query: 846  ----VGDHFGKGNG-LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV 900
                 G+     N  L  A    C G+E  L  C +V+H   +    R   V C+    +
Sbjct: 106  PPPAAGNTSVAANATLAGAPALLCSGAEWRL--CEVVEHACRS--DGRRARVTCAENRAL 161

Query: 901  RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV 960
            RLV+G   C G+VE+   G WGS+CD  WD EDA V+CRQL CG A+    G +      
Sbjct: 162  RLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG 221

Query: 961  RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS 1020
             +   + +C G E+ L +C   + G   C H                             
Sbjct: 222  PIHRDQVNCSGAEAYLWDCP-GLPGQHYCGH----------------------------- 251

Query: 1021 AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG 1080
               E +  +C E +  RL  G  RC G+VE++  G W T+CD  W  S+A V+CQ LGCG
Sbjct: 252  --KEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCG 309

Query: 1081 VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA 1140
             A            SG ++    +C G E  L  C  R    + C     A V+CS   +
Sbjct: 310  TAVERPKGLPHSL-SGRMY---YSCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRS 365

Query: 1141 LRLYSETE 1148
            L   S  E
Sbjct: 366  LHNLSTPE 373



 Score =  152 bits (383), Expect = 3e-36
 Identities = 108/333 (32%), Positives = 143/333 (42%), Gaps = 36/333 (10%)

Query: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGL------- 635
           +RL  GS+ CSG +EV  +  W   C   W+S+AA  VC  L C  +     L       
Sbjct: 45  VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104

Query: 636 ------GNASTGYGKIWLDDVS--CDGDESDLW-----SCRNSGWGNNDCSHSEDVGVIC 682
                 GN S           +  C G E  L      +CR+ G             V C
Sbjct: 105 PPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEVVEHACRSDG---------RRARVTC 155

Query: 683 SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSRE 742
             A +  LRLV G   CAG+VE+   G  G +C + W +  A VVCRQL CG A++    
Sbjct: 156 --AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPG 213

Query: 743 PHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADM 802
            HFT     I      C+G EA LWDC      Q  C    +A  +CS H+  RL G   
Sbjct: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGAD 272

Query: 803 PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862
            C G+VEV     W +VCDS++    A VLC+ L CG A+        G  + L+    +
Sbjct: 273 RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPK----GLPHSLSGRMYY 328

Query: 863 QCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
            C G E  L+ C    +  + C  S    V+CS
Sbjct: 329 SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361



 Score =  145 bits (366), Expect = 3e-34
 Identities = 124/410 (30%), Positives = 178/410 (43%), Gaps = 66/410 (16%)

Query: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG--------------- 1080
            +RL +G S C+G VE+  +  W   C   WD   A  VC+ LGCG               
Sbjct: 45   VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104

Query: 1081 ----VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHK-EDAGVIC 1135
                 A N +V+A+      P  L    C+G E  L +       +H CR     A V C
Sbjct: 105  PPPPAAGNTSVAANATLAGAPALL----CSGAEWRLCEVV-----EHACRSDGRRARVTC 155

Query: 1136 SEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLA 1195
            +E  ALRL       +CAGR+E+  +G WGSV         A +VCRQLGCG   V +L 
Sbjct: 156  AENRALRLVDGGG--ACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW-AVQALP 212

Query: 1196 PLSKT-GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRI-RVRGGDT 1253
             L  T G G +  D + C      +W C   P +       +   +  E +  R+ GG  
Sbjct: 213  GLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGAD 272

Query: 1254 ECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDM 1313
             C G+VE+   G W TVCD  W  +EA+V+CQ LGCG+A+   +       +G ++    
Sbjct: 273  RCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS-- 329

Query: 1314 RCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQ------------------------S 1349
             C G E  L +C  +    + C     A V CS                          +
Sbjct: 330  -CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTIESSVT 388

Query: 1350 LKSLNASSGHLALILSSI-FGLLLL--VLFILFLTWCRVQKQKHLPLRVS 1396
            +K  N  S  L L++ SI  G+LLL  ++FI F+   R++ +  LP+ V+
Sbjct: 389  VKIENKESRELMLLIPSIVLGILLLGSLIFIAFIL-LRIKGKYALPVMVN 437


>gi|5031863 galectin 3 binding protein [Homo sapiens]
          Length = 585

 Score =  120 bits (302), Expect = 7e-27
 Identities = 56/109 (51%), Positives = 74/109 (67%)

Query: 1031 LEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAH 1090
            + D  +RL DG +   GRVEI++ G WGT+CD+ WDL+DA VVC+ LG   A  A   A 
Sbjct: 19   VNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAA 78

Query: 1091 FGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFT 1139
            FG+GSGPI LD++ CTG E+ L  C S GW + +CRH+ DAGV+C+  T
Sbjct: 79   FGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNET 127



 Score =  110 bits (275), Expect = 1e-23
 Identities = 50/104 (48%), Positives = 71/104 (68%)

Query: 1246 IRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGT 1305
            +R+  G     GRVEI++ G WGTVCD+ WDL +A VVC+ LG  +A  AL  A+FGQG+
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1306 GTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQS 1349
            G I LD+++C G E+ L DC +  W +S+C H+ DAGV C+ ++
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNET 127



 Score =  100 bits (248), Expect = 1e-20
 Identities = 44/106 (41%), Positives = 62/106 (58%)

Query: 473 DLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFK 532
           D D+RL    +   GR+E+ Y+G+WGTVC + W   +A+VVC+ LG        G   F 
Sbjct: 21  DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFG 80

Query: 533 EASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGD 578
           + SGPI LD+V C G E+++ DC+  GW K NC H  D  V C+ +
Sbjct: 81  QGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNE 126



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 46/140 (32%), Positives = 72/140 (51%), Gaps = 13/140 (9%)

Query: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGY 642
           +RL  G     GR+E++++G+WGTVCD+ W+   A+VVC  L   ++   +G      G 
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 643 GKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS-------------DASDME 689
           G I LD+V C G E+ L  C++ GW  ++C H  D GV+C+             + S+  
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEAL 143

Query: 690 LRLVGGSSRCAGKVEVNVQG 709
            ++      C   + VNVQG
Sbjct: 144 GQIFDSQRGCDLSISVNVQG 163



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 45/108 (41%), Positives = 62/108 (57%), Gaps = 4/108 (3%)

Query: 45  DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAV 104
           D ++RL +G     G VE+ ++GQWGTVCD+ W+ T ++VVC+ LG  F  A    G+A 
Sbjct: 21  DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALG--FENATQALGRAA 78

Query: 105 TRHGK--IWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGE 150
              G   I LD+V C G E++L +C+   W   NC H  D GV C  E
Sbjct: 79  FGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNE 126



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 40/106 (37%), Positives = 59/106 (55%)

Query: 258 SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHL 317
           +D ++RL  G     GRVE+  +G+WGTVC + W+   A VVC+ LG   A    G    
Sbjct: 20  NDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79

Query: 318 QSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSD 363
             GS  + LD V C+G E+ L DC+  G +  +C H+ D  V+C++
Sbjct: 80  GQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTN 125



 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 38/100 (38%), Positives = 58/100 (58%)

Query: 155 LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVL 214
           +RL DG  +  GRVE+ ++ +WGT+CD+ W+L  A+VVCR LG  ++  + G        
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 215 RPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
            PI LD++ C G E +L +C+  GW   +C H  D  + C
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 40/106 (37%), Positives = 56/106 (52%)

Query: 366 DLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPS 425
           D ++RLADG     GRVE+    QW T+CD  W    A VVC+ LG   +     RA   
Sbjct: 21  DGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFG 80

Query: 426 NEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDK 471
             +  I ++ + CTG E++L DC   G  K  C    DAGV+C+++
Sbjct: 81  QGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNE 126



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 41/139 (29%), Positives = 64/139 (46%), Gaps = 15/139 (10%)

Query: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
           RL        GRVE+ +   W +VCD+ + L  A+V+CR L   +A        FG+G+G
Sbjct: 25  RLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSG 84

Query: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV--------------- 900
               ++ QC G+E  LA C  +   +  C H R+ GVVC+  T                 
Sbjct: 85  PIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALG 144

Query: 901 RLVNGKSQCDGQVEINVLG 919
           ++ + +  CD  + +NV G
Sbjct: 145 QIFDSQRGCDLSISVNVQG 163



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 35/102 (34%), Positives = 48/102 (47%)

Query: 899  DVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGER 958
            D+RL +G +   G+VEI   G WG++CD  WD  DA V+CR L    A    G    G+ 
Sbjct: 23   DMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQG 82

Query: 959  SVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
            S  +      C G E+ L +C+        C H     V+CT
Sbjct: 83   SGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 34/105 (32%), Positives = 55/105 (52%)

Query: 686 SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHF 745
           +D ++RL  G +   G+VE+  +G  G +C N W +  A VVCR L   +A +      F
Sbjct: 20  NDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79

Query: 746 TERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICS 790
            + +  I++    CTG EASL DC    W ++ C    +A ++C+
Sbjct: 80  GQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 2/95 (2%)

Query: 1154 GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLS-KTGSGFMWVDDIQC 1212
            GR+E+FY G WG+V         A +VCR LG  EN   +L   +   GSG + +D++QC
Sbjct: 35   GRVEIFYRGQWGTVCDNLWDLTDASVVCRALGF-ENATQALGRAAFGQGSGPIMLDEVQC 93

Query: 1213 PKTHISIWQCLSAPWERRISSPAEETWITCEDRIR 1247
              T  S+  C S  W +       +  + C +  R
Sbjct: 94   TGTEASLADCKSLGWLKSNCRHERDAGVVCTNETR 128


>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
            sapiens]
          Length = 451

 Score =  115 bits (288), Expect = 3e-25
 Identities = 60/150 (40%), Positives = 80/150 (53%)

Query: 987  PPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCA 1046
            PP + G+  ++   GS   P +      S P      +GS        ++RLV G     
Sbjct: 301  PPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHE 360

Query: 1047 GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCT 1106
            GRVEI H G WGTICDD W++    VVC+ LG         +AHFG+G+GPIWL+++ C 
Sbjct: 361  GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCF 420

Query: 1107 GMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            G ES + +C  R WG   C H EDAGV C+
Sbjct: 421  GRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  112 bits (280), Expect = 3e-24
 Identities = 48/102 (47%), Positives = 65/102 (63%)

Query: 1245 RIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQG 1304
            ++R+ GG     GRVEI H+G WGT+CDD W++   +VVC+ LG     A  + A FGQG
Sbjct: 349  KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 1305 TGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            TG IWL+++ C G ES + +C  + WG   C H EDAGV C+
Sbjct: 409  TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  107 bits (266), Expect = 1e-22
 Identities = 49/104 (47%), Positives = 64/104 (61%), Gaps = 6/104 (5%)

Query: 47  ELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFR---FGQA 103
           ++RLV G GP  G VE+   GQWGT+CDD W      VVC+ LG P   A+ +   FGQ 
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 104 VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
               G IWL++V C+G ES++ EC+ R+WG+  C H ED GV C
Sbjct: 409 T---GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449



 Score =  103 bits (256), Expect = 2e-21
 Identities = 45/101 (44%), Positives = 61/101 (60%)

Query: 476 LRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEAS 535
           +RLVG   P  GR+E+ + G+WGT+C DRW  R   VVC+ LG      V    +F + +
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 536 GPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS 576
           GPIWL++V C G ES+I +C+   WG   C H ED  VTC+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 44/101 (43%), Positives = 56/101 (55%)

Query: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGY 642
           +RLVGGS    GR+E+   G+WGT+CDD W  +   VVC  L  P         +   G 
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 643 GKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
           G IWL++V C G ES +  C+   WG   CSHSED GV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 91.7 bits (226), Expect = 5e-18
 Identities = 41/100 (41%), Positives = 55/100 (55%)

Query: 155 LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVL 214
           +RLV G+    GRVE+    +WGTICDD W +    VVCR LG P         +     
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 215 RPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
            PIWL+++ C G E ++  C+ R WG   CSH+ED  +TC
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 35/100 (35%), Positives = 50/100 (50%)

Query: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
           RLVG   P  GRVE+ H+  W ++CD  + +    V+CR L      ++    HFG+G G
Sbjct: 351 RLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTG 410

Query: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
             W  +  C G E+ +  C I Q     C HS + GV C+
Sbjct: 411 PIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 34/110 (30%), Positives = 53/110 (48%)

Query: 891  GVVCSRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTT 950
            G   + +T VRLV G    +G+VEI   G WG++CD  W+    +V+CR L      +  
Sbjct: 341  GNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVH 400

Query: 951  GGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
               + G+ +  +W +   C G ES ++ C++   G   C H     V CT
Sbjct: 401  KAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 35/102 (34%), Positives = 50/102 (49%)

Query: 261 ELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSG 320
           ++RLVGG+    GRVE+   G+WGT+C  +W      VVC+ LG           H   G
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 321 SDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
           +  +WL+ V C G ES + +C+        C H  D  V C+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 37/102 (36%), Positives = 49/102 (48%)

Query: 368 ELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNE 427
           ++RL  GS    GRVE+    QW TICD  W+     VVC+ LG P      + A     
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 428 ARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
              IW+N + C G ES++ +C       R C    DAGV C+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 33/102 (32%), Positives = 54/102 (52%)

Query: 689 ELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTER 748
           ++RLVGGS    G+VE+   G  G +C + W + + +VVCR L       V +  HF + 
Sbjct: 349 KVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQG 408

Query: 749 TLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICS 790
           T  I ++   C G E+S+ +C   +W   AC  + +A + C+
Sbjct: 409 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 2/115 (1%)

Query: 1128 KEDAGVICSEFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187
            ++ +G   + FT +RL   +      GR+E+ ++G WG++        +  +VCR LG  
Sbjct: 337  EKGSGNTLTPFTKVRLVGGSGPHE--GRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYP 394

Query: 1188 ENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITC 1242
                V  A     G+G +W++++ C     SI +C    W  R  S +E+  +TC
Sbjct: 395  GVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score =  114 bits (284), Expect = 9e-25
 Identities = 53/107 (49%), Positives = 65/107 (60%), Gaps = 5/107 (4%)

Query: 577 GDATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLG 636
           G+ +  +R+VG SNR  GR EVY+ G WGT+CDD W +  A V C  L       G  L 
Sbjct: 418 GENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSK---GRALY 472

Query: 637 NASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
               G G+IWLD+V C G ES LWSC  + WG++DCSH ED GV CS
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  109 bits (273), Expect = 2e-23
 Identities = 47/104 (45%), Positives = 65/104 (62%), Gaps = 3/104 (2%)

Query: 1243 EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFG 1302
            E+ + VR   +   GR E++++G+WGT+CDD W  ++A V C+ LG     A  +    G
Sbjct: 419  ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYK---VG 475

Query: 1303 QGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
             GTG IWLD+++C+G ES LW C    WG  DC H+EDAGV CS
Sbjct: 476  AGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (269), Expect = 5e-23
 Identities = 50/101 (49%), Positives = 60/101 (59%), Gaps = 5/101 (4%)

Query: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGS 1095
            +R+V   +R  GR E+Y+ G WGTICDD W  SDA V C+ LG             G G+
Sbjct: 424  VRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYS---KGRALYKVGAGT 478

Query: 1096 GPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            G IWLD++ C G ES LW C    WG HDC H+EDAGV CS
Sbjct: 479  GQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 40/89 (44%), Positives = 51/89 (57%), Gaps = 3/89 (3%)

Query: 59  GTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCY 118
           G  EV + G WGT+CDD W  + + V C+ LG     A+++ G      G+IWLD+V C 
Sbjct: 433 GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGT---GQIWLDNVQCR 489

Query: 119 GNESALWECQHREWGSHNCYHGEDVGVNC 147
           G ES LW C    WG H+C H ED GV C
Sbjct: 490 GTESTLWSCTKNSWGHHDCSHEEDAGVEC 518



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 45/105 (42%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 474 LDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFK- 532
           + +R+VG+ +   GR EV Y G WGT+C D W   +A V C+ LG  K     G   +K 
Sbjct: 422 VSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSK-----GRALYKV 474

Query: 533 -EASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS 576
              +G IWLD+V C G ES +W C  + WG H+C H ED  V CS
Sbjct: 475 GAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 44/106 (41%), Positives = 58/106 (54%), Gaps = 5/106 (4%)

Query: 149 GEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVV 208
           GE ++ +R+V  +N   GR EV +   WGTICDD W  + A V CR LG         + 
Sbjct: 418 GENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG---RALY 472

Query: 209 NSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
              A    IWLD++ C+G E  LW+C    WG+HDCSH ED  + C
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 43/107 (40%), Positives = 60/107 (56%), Gaps = 9/107 (8%)

Query: 258 SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGC--GTALHFAGLP 315
           + + +R+VG +NR  GR E+   G WGT+C  +W N+ A V C+ LG   G AL+  G  
Sbjct: 420 NSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVG-- 475

Query: 316 HLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
              +G+  +WLD V C G ES LW C  +   + DC H+ D  V CS
Sbjct: 476 ---AGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 39/105 (37%), Positives = 51/105 (48%), Gaps = 9/105 (8%)

Query: 367 LELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRA--KP 424
           + +R+   SN   GR EV     W TICD  W+N  A+V C+ LG     +   RA  K 
Sbjct: 422 VSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG-----YSKGRALYKV 474

Query: 425 SNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
                 IW++++ C G ES LW CT +      C    DAGV CS
Sbjct: 475 GAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 3/89 (3%)

Query: 1154 GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCP 1213
            GR EV+Y+GTWG++       + A + CR LG  +   +        G+G +W+D++QC 
Sbjct: 433  GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVG---AGTGQIWLDNVQCR 489

Query: 1214 KTHISIWQCLSAPWERRISSPAEETWITC 1242
             T  ++W C    W     S  E+  + C
Sbjct: 490  GTESTLWSCTKNSWGHHDCSHEEDAGVEC 518



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 33/100 (33%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
           R+VG+     GR EV ++ TW ++CD ++    A V CR L      +L      G G G
Sbjct: 425 RIVGSSN--RGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY---KVGAGTG 479

Query: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
             W +  QC G+E+ L  C         C H  + GV CS
Sbjct: 480 QIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 34/103 (33%), Positives = 47/103 (45%), Gaps = 9/103 (8%)

Query: 900  VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQL--SCGTALSTTGGKYIGE 957
            VR+V   ++  G+ E+   G WG++CD  W   DA V CR L  S G AL       +G 
Sbjct: 424  VRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYK-----VGA 476

Query: 958  RSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
             + ++W     C G ES L +C     G   C H     V C+
Sbjct: 477  GTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 5/105 (4%)

Query: 686 SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHF 745
           + + +R+VG S+R  G+ EV   G  G +C + W  + A V CR L       + +    
Sbjct: 420 NSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAG 477

Query: 746 TERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICS 790
           T +   I + N  C G E++LW C +  W    C    +A + CS
Sbjct: 478 TGQ---IWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519


>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
          Length = 495

 Score =  114 bits (284), Expect = 9e-25
 Identities = 49/101 (48%), Positives = 62/101 (61%)

Query: 1246 IRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGT 1305
            IR+  G     GRVE++H   WGTVCDD WD  + +VVC+ LG        R A FGQGT
Sbjct: 393  IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 1306 GTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            G IW+DD+ CKG E  ++ C    WG ++CGH EDA V C+
Sbjct: 453  GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (276), Expect = 8e-24
 Identities = 48/101 (47%), Positives = 63/101 (62%)

Query: 1036 LRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGS 1095
            +RLV+G     GRVE+YHD  WGT+CDDGWD  D  VVC+ LG         +A FG+G+
Sbjct: 393  IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 1096 GPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            G IW+DD+ C G E  +++C    WG  +C H EDA V C+
Sbjct: 453  GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  102 bits (254), Expect = 3e-21
 Identities = 48/103 (46%), Positives = 59/103 (57%), Gaps = 6/103 (5%)

Query: 48  LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQL---GCPFSFAMFRFGQAV 104
           +RLVNG GP  G VEV    +WGTVCDDGW+     VVC+ L   G    +   RFGQ  
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 105 TRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
              G+IW+DDV+C G E  ++ C   +WG  NC H ED  V C
Sbjct: 453 ---GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492



 Score = 99.0 bits (245), Expect = 3e-20
 Identities = 47/113 (41%), Positives = 62/113 (54%)

Query: 464 AGVICSDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPM 523
           AG     +A + +RLV    P  GR+EV +   WGTVC D W  ++  VVC+ LG     
Sbjct: 381 AGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVE 440

Query: 524 HVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS 576
            V+    F + +G IW+DDV+C G E  I+ C  S WG  NC H ED  VTC+
Sbjct: 441 EVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 46/106 (43%), Positives = 58/106 (54%)

Query: 578 DATWGLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGN 637
           +A   +RLV GS    GR+EVY   RWGTVCDDGW+ K   VVC  L             
Sbjct: 388 EAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTAR 447

Query: 638 ASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
              G G+IW+DDV+C G E  ++ C  S WG  +C H+ED  V C+
Sbjct: 448 FGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 42/105 (40%), Positives = 56/105 (53%)

Query: 150 EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVN 209
           EA + +RLV+G+    GRVEV    RWGT+CDDGW+     VVCR LG            
Sbjct: 388 EAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTAR 447

Query: 210 SPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
                  IW+DD+ C+G E  ++ C    WG  +C H ED ++TC
Sbjct: 448 FGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 4/111 (3%)

Query: 256 DSSDLE----LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHF 311
           D+S +E    +RLV G+    GRVE+    RWGTVC   W+    DVVC+ LG       
Sbjct: 383 DASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEV 442

Query: 312 AGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
                   G+  +W+D V+C G E  ++ C  S     +C H  D SV C+
Sbjct: 443 YRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 33/105 (31%), Positives = 50/105 (47%)

Query: 365 ADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKP 424
           A + +RL +GS    GRVEV    +W T+CD  W  +   VVC+ LG        R A+ 
Sbjct: 389 APMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARF 448

Query: 425 SNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
                 IW++ ++C G E  ++ C++       C    DA V C+
Sbjct: 449 GQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 32/100 (32%), Positives = 45/100 (45%)

Query: 900 VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERS 959
           +RLVNG    +G+VE+     WG++CD  WD +D  V+CR L              G+ +
Sbjct: 393 IRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGT 452

Query: 960 VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVIC 999
            R+W     C G E  +  C  +  G   C H    SV C
Sbjct: 453 GRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 32/102 (31%), Positives = 47/102 (46%)

Query: 796 RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNG 855
           RLV    P  GRVEV H   W +VCD  +     +V+CR L       +     FG+G G
Sbjct: 394 RLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTG 453

Query: 856 LTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY 897
             W +   C+G+E  +  C   +     C H+ +  V C+R+
Sbjct: 454 RIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNRH 495



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 4/113 (3%)

Query: 684 DASDME----LRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRV 739
           DAS +E    +RLV GS    G+VEV      G +C +GW     +VVCR L       V
Sbjct: 383 DASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEV 442

Query: 740 SREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792
            R   F + T  I M +  C G E +++ C   +W  T C    +AS+ C+ H
Sbjct: 443 YRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCNRH 495



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 1154 GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC-GENGVVSLAPLSKTGSGFMWVDDIQC 1212
            GR+EV+++  WG+V           +VCR LG  G   V   A   + G+G +W+DD+ C
Sbjct: 404  GRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQ-GTGRIWMDDVAC 462

Query: 1213 PKTHISIWQCLSAPWERRISSPAEETWITC 1242
              T  +I++C  + W       AE+  +TC
Sbjct: 463  KGTEETIFRCSFSKWGVTNCGHAEDASVTC 492


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score =  108 bits (271), Expect = 3e-23
 Identities = 56/114 (49%), Positives = 71/114 (62%), Gaps = 3/114 (2%)

Query: 1026 SALICLEDKRLRLVD--GDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAF 1083
            SA     D  +RLV   G S  +GRVE++  G WGT+CDD W++S A VVC++LG   A 
Sbjct: 663  SASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAV 722

Query: 1084 NATVSAHFGE-GSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
             A   A FG+ GS PI LDD+ C G E +L +C   G G H+C H EDAGV+CS
Sbjct: 723  RAVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 53/108 (49%), Positives = 68/108 (62%), Gaps = 1/108 (0%)

Query: 1243 EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFG 1302
            E R+    G +  SGRVE++  G WGTVCDDSW+++ A VVC+QLG   A+ A++ A FG
Sbjct: 672  EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731

Query: 1303 QGTG-TIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQS 1349
            QG    I LDD+RC G E  L +C     G  +C H EDAGV CS Q+
Sbjct: 732  QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQN 779



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 54/108 (50%), Positives = 65/108 (60%), Gaps = 7/108 (6%)

Query: 45  DLELRLVNGDGPCSGT--VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQ 102
           D E+RLV   G  SG+  VEV   G+WGTVCDD WN + + VVC+QLG  F++A+    +
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLG--FAYAVRAVKR 727

Query: 103 AVTRHG---KIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
           A    G    I LDDV C G E  L ECQH   G+HNC H ED GV C
Sbjct: 728 AEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVC 775



 Score = 92.4 bits (228), Expect = 3e-18
 Identities = 50/106 (47%), Positives = 64/106 (60%), Gaps = 7/106 (6%)

Query: 583 LRLV--GGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAST 640
           +RLV   G +  SGR+EV+  GRWGTVCDD WN   AAVVC QL    ++    +  A  
Sbjct: 673 VRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAV--RAVKRAEF 730

Query: 641 GYG---KIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
           G G    I LDDV C G E +L  C+++G G ++C H ED GV+CS
Sbjct: 731 GQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 91.3 bits (225), Expect = 6e-18
 Identities = 44/91 (48%), Positives = 53/91 (58%), Gaps = 1/91 (1%)

Query: 487 GRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASG-PIWLDDVSC 545
           GR+EV   G WGTVC D W+   AAVVC+QLG    +       F +    PI LDDV C
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 546 IGNESNIWDCEHSGWGKHNCVHREDVIVTCS 576
            G E N+ +C+H+G G HNC H ED  V CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 46/97 (47%), Positives = 57/97 (58%), Gaps = 3/97 (3%)

Query: 160 GNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSF--ISSGVVNSPAVLRPI 217
           G +S SGRVEV    RWGT+CDD WN++ AAVVCRQLG   +   +          L PI
Sbjct: 680 GLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSL-PI 738

Query: 218 WLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
            LDD+ C G E  L  C+H G G H+C H+ED  + C
Sbjct: 739 LLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVC 775



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 46/107 (42%), Positives = 60/107 (56%), Gaps = 3/107 (2%)

Query: 259 DLELRLV--GGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPH 316
           D E+RLV   G +   GRVE+ + GRWGTVC   WN + A VVC+QLG   A+       
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 317 L-QSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
             Q GS  + LD V C+G E  L +C+H+G    +C H  D  V+CS
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 40/107 (37%), Positives = 60/107 (56%), Gaps = 3/107 (2%)

Query: 366 DLELRLAD--GSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAK 423
           D E+RL    G ++ SGRVEV +  +W T+CD +W    A VVC+QLG  ++V   +RA+
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 424 -PSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
                +  I ++ + C G E  L +C ++G     C    DAGV+CS
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 41/114 (35%), Positives = 61/114 (53%), Gaps = 4/114 (3%)

Query: 687 DMELRLV--GGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPH 744
           D E+RLV   G S  +G+VEV V G  G +C + W ++ A VVCRQL    A+R  +   
Sbjct: 670 DGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAE 729

Query: 745 FTE-RTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRL 797
           F +  +L IL+ +  C G E +L +C         C  + +A ++CS H+ P L
Sbjct: 730 FGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS-HQNPDL 782



 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 3/105 (2%)

Query: 899  DVRLVN--GKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
            +VRLV   G S   G+VE+ V G WG++CD  W+   A V+CRQL    A+        G
Sbjct: 672  EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731

Query: 957  E-RSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
            +  S+ +      C G E  L  CQ   +G   C H     V+C+
Sbjct: 732  QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 1/92 (1%)

Query: 805 SGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGL-TWAEKFQ 863
           SGRVEV     W +VCD  +++  A V+CR+L    A+       FG+G  L    +  +
Sbjct: 685 SGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVR 744

Query: 864 CEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
           C G E +L  C         C H  + GVVCS
Sbjct: 745 CAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 27/83 (32%), Positives = 42/83 (50%), Gaps = 1/83 (1%)

Query: 1141 LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG-ENGVVSLAPLSK 1199
            +RL       S +GR+EVF  G WG+V   +   + A +VCRQLG       V  A   +
Sbjct: 673  VRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQ 732

Query: 1200 TGSGFMWVDDIQCPKTHISIWQC 1222
             GS  + +DD++C     ++ +C
Sbjct: 733  GGSLPILLDDVRCAGWERNLLEC 755


>gi|166197668 CD5 molecule [Homo sapiens]
          Length = 495

 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 84/339 (24%), Positives = 128/339 (37%), Gaps = 73/339 (21%)

Query: 571 VIVTCSGDATW-----GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKA--------A 617
           ++ +C G  +W       RL   +++C G+LEVY +  W  VC   W   +        A
Sbjct: 18  LVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQA 77

Query: 618 AVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSED 677
           + VC +L+C    + + LG     Y       + C G      +C +S    ND  HS  
Sbjct: 78  SKVCQRLNCG---VPLSLGPFLVTYTP--QSSIICYGQLGSFSNCSHS---RNDMCHS-- 127

Query: 678 VGVICSDASD---------------------MELRLVGGSSRCAGKVEVNVQGAVGILC- 715
           +G+ C +                        ++L    G   CAG VE       G +  
Sbjct: 128 LGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISY 187

Query: 716 -ANGWGMNIAEVVCRQLECGSAIRVSREP------------HFTERTLHILMSNSGCTGG 762
            A     ++   +C  L+CGS ++   E                   +   + NS CT  
Sbjct: 188 EAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCT-- 245

Query: 763 EASLWDCIRWEWKQTACHLNMEASLICSAHR---QPRLVGADMPCSGRVEVKHADTWRSV 819
             SL  C R    Q +  +    +L+CS  +   Q RLVG    C G VEV+    W ++
Sbjct: 246 --SLEHCFRKIKPQKSGRV---LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300

Query: 820 CDSDFSLHAA--NVLCRELNCGDAIS---LSVGDHFGKG 853
           CDS  +  +     +CRE  CG   S   L  GD   +G
Sbjct: 301 CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRG 339



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 78/308 (25%), Positives = 120/308 (38%), Gaps = 61/308 (19%)

Query: 473 DLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRN--------AAVVCKQLGCGKPMH 524
           D   RL  ++S C G+LEV  +  W  VC   W   +        A+ VC++L CG P+ 
Sbjct: 32  DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91

Query: 525 V--FGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVH--------------- 567
           +  F +TY  ++S       + C G   +  +C HS   +++  H               
Sbjct: 92  LGPFLVTYTPQSS-------IICYGQLGSFSNCSHS---RNDMCHSLGLTCLEPQKTTPP 141

Query: 568 --REDVIVTCSGDATWGLRLV--GGSNRCSGRLEVYFQGRWGTVCDDGWN--SKAAAVVC 621
             R     T    A   L+LV   G   C+G +E Y     GT+  +  +        +C
Sbjct: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLC 201

Query: 622 SQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDL---WSCRNSGWGN-NDC----- 672
           + L C S +  +      T  G+    D     +   L   W  +NS   +   C     
Sbjct: 202 NNLQCGSFLKHL----PETEAGR--AQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIK 255

Query: 673 --SHSEDVGVICSD-ASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIA--EVV 727
                  + ++CS     ++ RLVGGSS C G VEV        LC +    +    E V
Sbjct: 256 PQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV 315

Query: 728 CRQLECGS 735
           CR+ +CGS
Sbjct: 316 CREQQCGS 323



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 90/381 (23%), Positives = 142/381 (37%), Gaps = 85/381 (22%)

Query: 156 RLVDGNNSCSGRVEVKFQERWGTICDDGWNLNT--------AAVVCRQLGC--PSSFISS 205
           RL   N+ C G++EV  ++ W  +C   W  ++        A+ VC++L C  P S    
Sbjct: 36  RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPF 95

Query: 206 GVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSD------ 259
            V  +P          I+C G   +  NC H     +D  H+  + LTC +         
Sbjct: 96  LVTYTPQ-------SSIICYGQLGSFSNCSH---SRNDMCHS--LGLTCLEPQKTTPPTT 143

Query: 260 ---------------LELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAA--ADVVCKQ 302
                          L+L    G   C G VE       GT+ +   +      + +C  
Sbjct: 144 RPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNN 203

Query: 303 LGCGTALHFAGLPHLQSGS-------------DVVW-LDGVSCSGNESFLWDCR--HSGT 346
           L CG+ L    LP  ++G               + W +   SC+  E      +   SG 
Sbjct: 204 LQCGSFLKH--LPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGR 261

Query: 347 VNFDCLHQNDVSVICSD-GADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQAL- 404
           V         ++++CS     ++ RL  GS+ C G VEVR   QW  +CD +        
Sbjct: 262 V---------LALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRW 312

Query: 405 -VVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESA----LWD-CTYDGKAKRTC 458
             VC++  C     GS  +    +A D     + C   + +    LW+  +Y  K   TC
Sbjct: 313 EEVCREQQC-----GSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTC 367

Query: 459 FRRSDAGVICSDKADLDLRLV 479
              + AG+     A + L LV
Sbjct: 368 QDPNPAGLAAGTVASIILALV 388



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 78/314 (24%), Positives = 120/314 (38%), Gaps = 77/314 (24%)

Query: 1033 DKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGW--------DLSDAHVVCQKLGCGVAFN 1084
            D + RL   +S+C G++E+Y    W  +C   W        D S A  VCQ+L CGV  +
Sbjct: 32   DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLS 91

Query: 1085 ATVSAHFGEGSGPIWL-----DDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVIC---- 1135
                       GP  +       + C G       C      ++D  H    G+ C    
Sbjct: 92   L----------GPFLVTYTPQSSIICYGQLGSFSNC---SHSRNDMCH--SLGLTCLEPQ 136

Query: 1136 --------------SEFTA---LRLYSETETESCAGRLEVFYNGTWG---SVGRRNITTA 1175
                           E TA   L+L +++  + CAG +E FY+G+ G   S   ++ T  
Sbjct: 137  KTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVE-FYSGSLGGTISYEAQDKTQD 195

Query: 1176 IAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISI---WQ-----CLSAPW 1227
            +   +C  L CG      L  L +T +G     D   P+ H  +   W+     C S   
Sbjct: 196  LENFLCNNLQCGS----FLKHLPETEAG--RAQDPGEPREHQPLPIQWKIQNSSCTSLEH 249

Query: 1228 ERRISSPAEETWITC--------EDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAE 1279
              R   P +   +          + + R+ GG + C G VE+     W  +CD S   + 
Sbjct: 250  CFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSS 309

Query: 1280 A--EVVCQQLGCGS 1291
               E VC++  CGS
Sbjct: 310  LRWEEVCREQQCGS 323



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 89/376 (23%), Positives = 140/376 (37%), Gaps = 74/376 (19%)

Query: 901  RLVNGKSQCDGQVEINVLGHWGSLCDTHW--------DPEDARVLCRQLSCGTALSTTGG 952
            RL    S+C GQ+E+ +   W  +C   W        DP  A  +C++L+CG  LS   G
Sbjct: 36   RLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSL--G 93

Query: 953  KYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLA 1012
             ++   + +       C G      NC  +        H   ++ +     T P      
Sbjct: 94   PFLVTYTPQ---SSIICYGQLGSFSNCSHS---RNDMCHSLGLTCLEPQKTTPP------ 141

Query: 1013 NVSDPYLSAVPEGSALICLEDKRLRLV--DGDSRCAGRVEIYHDGFWGTICDDGWDLSD- 1069
              + P  +  PE +A       RL+LV   G   CAG VE Y     GTI  +  D +  
Sbjct: 142  -TTRPPPTTTPEPTA-----PPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQD 195

Query: 1070 -AHVVCQKLGCGVAFNATVSAHFGEGSGP-----------IW-LDDLNCTGMESHLWQCP 1116
              + +C  L CG           G    P            W + + +CT +E    +  
Sbjct: 196  LENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIK 255

Query: 1117 SRGWGQHDCRHKEDAGVICSEF---TALRLYSETETESCAGRLEVFYNGTWGSVGRRNIT 1173
             +  G+          ++CS F      RL   +    C G +EV     W ++   + +
Sbjct: 256  PQKSGR-------VLALLCSGFQPKVQSRLVGGSSI--CEGTVEVRQGAQWAAL--CDSS 304

Query: 1174 TAIAGI----VCRQLGCGE-NGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWE 1228
            +A + +    VCR+  CG  N    L     T  G        CP  H  + QC    WE
Sbjct: 305  SARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLF------CP--HQKLSQCHEL-WE 355

Query: 1229 RRISSPAEETWITCED 1244
            R  +S  ++ ++TC+D
Sbjct: 356  R--NSYCKKVFVTCQD 369



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 78/320 (24%), Positives = 121/320 (37%), Gaps = 74/320 (23%)

Query: 252 LTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAA--------ADVVCKQL 303
           L+ YD  D + RL    ++C G++E+ ++  W  VC   W  ++        A  VC++L
Sbjct: 26  LSWYDP-DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRL 84

Query: 304 GCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHS-----GTVNFDCLHQNDVS 358
            CG  L     P L + +       + C G      +C HS      ++   CL     +
Sbjct: 85  NCGVPLSLG--PFLVTYTP---QSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTT 139

Query: 359 VICSDGAD-----------LELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQAL--V 405
              +               L+L    G  +C+G VE        TI  +     Q L   
Sbjct: 140 PPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENF 199

Query: 406 VCKQLGC-------PFSVFGSRRAKPSNEARD------IW-INSISCTGNESALWDCTYD 451
           +C  L C       P +  G  RA+   E R+       W I + SCT  E         
Sbjct: 200 LCNNLQCGSFLKHLPETEAG--RAQDPGEPREHQPLPIQWKIQNSSCTSLEH-------- 249

Query: 452 GKAKRTCFRRSD-------AGVICSD-KADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHD 503
                 CFR+           ++CS  +  +  RLVG  S C G +EV+   +W  +C D
Sbjct: 250 ------CFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALC-D 302

Query: 504 RWSTRNA---AVVCKQLGCG 520
             S R++     VC++  CG
Sbjct: 303 SSSARSSLRWEEVCREQQCG 322



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 74/311 (23%), Positives = 114/311 (36%), Gaps = 65/311 (20%)

Query: 687 DMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNI--------AEVVCRQLECGSAIR 738
           D + RL   +S+C G++EV ++    ++C+  WG +         A  VC++L CG  + 
Sbjct: 32  DFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCG--VP 89

Query: 739 VSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ---- 794
           +S  P     T     S+  C G   S  +C     +   CH      L C   ++    
Sbjct: 90  LSLGPFLVTYTPQ---SSIICYGQLGSFSNCSHS--RNDMCH---SLGLTCLEPQKTTPP 141

Query: 795 ---------------PRLV----GADMPCSGRVEVKHADTWRSVC--DSDFSLHAANVLC 833
                          PRL          C+G VE        ++     D +    N LC
Sbjct: 142 TTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLC 201

Query: 834 RELNCGDAISLSVGDHFGKGNG-----------LTWAEKFQCEGSETHLALCPIVQHPED 882
             L CG  +        G+              + W  K Q   S T L  C     P+ 
Sbjct: 202 NNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQW--KIQ-NSSCTSLEHCFRKIKPQK 258

Query: 883 TCIHSREVGVVCSRY---TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDAR--VL 937
           +    R + ++CS +      RLV G S C+G VE+     W +LCD+       R   +
Sbjct: 259 S---GRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEV 315

Query: 938 CRQLSCGTALS 948
           CR+  CG+  S
Sbjct: 316 CREQQCGSVNS 326



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 67/320 (20%), Positives = 115/320 (35%), Gaps = 55/320 (17%)

Query: 30  LLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTA-------- 81
           +L+ SC    S+   D + RL   +  C G +EV  +  W  VC   W  ++        
Sbjct: 17  MLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQ 76

Query: 82  STVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGE 141
           ++ VC++L C    ++  F    T    I      CYG   +   C H    +  C+   
Sbjct: 77  ASKVCQRLNCGVPLSLGPFLVTYTPQSSI-----ICYGQLGSFSNCSHSR--NDMCH--- 126

Query: 142 DVGVNCY---------------------GEANLGLRLVDGNNSCSGRVEVKFQERWGTIC 180
            +G+ C                          L L    G   C+G VE       GTI 
Sbjct: 127 SLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTIS 186

Query: 181 DDGWN--LNTAAVVCRQLGCPSSF-----ISSGVVNSPAVLR---PIWLDDILCQGNELA 230
            +  +   +    +C  L C S         +G    P   R   P+ +   +   +  +
Sbjct: 187 YEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTS 246

Query: 231 LWNCRHRGWGNHDCSHNEDVTLTCYD-SSDLELRLVGGTNRCMGRVELKIQGRWGTVCHH 289
           L +C  +            + L C      ++ RLVGG++ C G VE++   +W  +C  
Sbjct: 247 LEHCFRK---IKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDS 303

Query: 290 KWNNAAA--DVVCKQLGCGT 307
               ++   + VC++  CG+
Sbjct: 304 SSARSSLRWEEVCREQQCGS 323



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 8/65 (12%)

Query: 1238 TWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSW--------DLAEAEVVCQQLGC 1289
            +W   + + R+   +++C G++E++    W  VC  SW        D ++A  VCQ+L C
Sbjct: 27   SWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNC 86

Query: 1290 GSALA 1294
            G  L+
Sbjct: 87   GVPLS 91


>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
           sapiens]
          Length = 388

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 21/40 (52%), Positives = 29/40 (72%)

Query: 108 GKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC 147
           G IWL++V C+G ES++ EC+ R+WG+  C H ED GV C
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 21/42 (50%), Positives = 28/42 (66%)

Query: 1095 SGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS 1136
            +GPIWL+++ C G ES + +C  R WG   C H EDAGV C+
Sbjct: 346  TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 21/43 (48%), Positives = 29/43 (67%)

Query: 534 ASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCS 576
           ++GPIWL++V C G ES+I +C+   WG   C H ED  VTC+
Sbjct: 345 STGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 24/50 (48%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 634 GLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS 683
           G GN +   G IWL++V C G ES +  C+   WG   CSHSED GV C+
Sbjct: 339 GSGN-TLSTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 20/42 (47%), Positives = 27/42 (64%)

Query: 1305 TGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
            TG IWL+++ C G ES + +C  + WG   C H EDAGV C+
Sbjct: 346  TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/39 (46%), Positives = 26/39 (66%)

Query: 216 PIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTC 254
           PIWL+++ C G E ++  C+ R WG   CSH+ED  +TC
Sbjct: 348 PIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386



 Score = 38.1 bits (87), Expect = 0.062
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 431 IWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS 469
           IW+N + C G ES++ +C       R C    DAGV C+
Sbjct: 349 IWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 4/49 (8%)

Query: 851 GKGNGLT----WAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS 895
           G GN L+    W  +  C G E+ +  C I Q     C HS + GV C+
Sbjct: 339 GSGNTLSTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 12/39 (30%), Positives = 18/39 (46%)

Query: 962  VWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICT 1000
            +W +   C G ES ++ C++   G   C H     V CT
Sbjct: 349  IWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 324 VWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS 362
           +WL+ V C G ES + +C+        C H  D  V C+
Sbjct: 349 IWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 387


>gi|119392081 complement factor I preproprotein [Homo sapiens]
          Length = 583

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 46/156 (29%), Positives = 70/156 (44%), Gaps = 20/156 (12%)

Query: 329 VSCSGNESFLWDCRHSGTVNFDCLHQNDVSV---ICSDGADLELRLADGSNNCSGRVEVR 385
           V  +   SF   C+     + +CLH     +    C+      + L  G+ +  G VEV+
Sbjct: 74  VCATNRRSFPTYCQQK---SLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVK 130

Query: 386 IHEQWWT--ICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINS-----ISC 438
           + +Q  T  IC  +W   +A V C  LG        RR K S    D+ INS     + C
Sbjct: 131 LVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLS----DLSINSTECLHVHC 186

Query: 439 TGNESALWDCTYDGKAKRTCFRRSDAGVIC-SDKAD 473
            G E++L +CT+    +RT   +  A V+C + KAD
Sbjct: 187 RGLETSLAECTF--TKRRTMGYQDFADVVCYTQKAD 220



 Score = 37.7 bits (86), Expect = 0.081
 Identities = 34/120 (28%), Positives = 46/120 (38%), Gaps = 21/120 (17%)

Query: 127 CQHREWGSHNCYHGEDVGVN---CYGEANLGLRLVDGNNSCSGRVEVKF--QERWGTICD 181
           CQ +   S  C H     +N   C  E    + L  GN    G VEVK   Q++   IC 
Sbjct: 86  CQQK---SLECLHPGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICK 142

Query: 182 DGWNLNTAAVVCRQLGCPSSF-------ISSGVVNSPAVLRPIWLDDILCQGNELALWNC 234
             W++  A V C  LG            +S   +NS   L       + C+G E +L  C
Sbjct: 143 SSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLH------VHCRGLETSLAEC 196



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 30/120 (25%), Positives = 44/120 (36%), Gaps = 25/120 (20%)

Query: 1246 IRVRGGDTECSGRVEIWHAGSWGT--VCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQ 1303
            + ++ G+T+  G VE+       T  +C  SW + EA V C  LG            F Q
Sbjct: 114  VSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLG------------FQQ 161

Query: 1304 GTGT---IWLDDMRCKGNESFLWDCHAKPWGQSDC--------GHKEDAGVRCSGQSLKS 1352
            G  T     L D+     E     C       ++C        G+++ A V C  Q   S
Sbjct: 162  GADTQRRFKLSDLSINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQKADS 221



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 21/90 (23%)

Query: 50  LVNGDGPCSGTVEVKFQGQWGT--VCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRH 107
           L +G+    G VEVK   Q  T  +C   W+   + V C  LG         F Q     
Sbjct: 116 LKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLG---------FQQGADTQ 166

Query: 108 GKIWLDDVS----------CYGNESALWEC 127
            +  L D+S          C G E++L EC
Sbjct: 167 RRFKLSDLSINSTECLHVHCRGLETSLAEC 196


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score = 40.8 bits (94), Expect = 0.010
 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 361 CSDGADLE--LRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
           C DG+D    +R  +G+ N +G V  RI   W T C +NW  + +  VC+ LG
Sbjct: 668 CEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLG 720



 Score = 40.4 bits (93), Expect = 0.013
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 2/61 (3%)

Query: 249 DVTLTCYDSSDLE--LRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCG 306
           D  L C D SD    +R   GT    G V  +IQ  W T C   W    ++ VC+ LG G
Sbjct: 663 DGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLG 722

Query: 307 T 307
           +
Sbjct: 723 S 723



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 28  CILLLNSCF-LISSFNGTDLE--LRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTV 84
           C+ L+N C   +   +G+D    +R  NG    +G V  + Q  W T C + W T  S  
Sbjct: 655 CVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISND 714

Query: 85  VCKQLG 90
           VC+ LG
Sbjct: 715 VCQLLG 720



 Score = 35.8 bits (81), Expect = 0.31
 Identities = 38/149 (25%), Positives = 61/149 (40%), Gaps = 27/149 (18%)

Query: 469 SDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCG-----KPM 523
           SD+AD  +R     +   G +  + Q  W T C + W+T+ +  VC+ LG G     KP+
Sbjct: 672 SDEADC-VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPI 730

Query: 524 -HVFGMTYFKEASGP----IWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGD 578
               G  + K  + P    I      C+ +      C H   GK   +  +D+       
Sbjct: 731 FSTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKK--LAAQDITP----- 783

Query: 579 ATWGLRLVGGSNRCSGR----LEVYFQGR 603
                ++VGGSN   G     + +Y+ GR
Sbjct: 784 -----KIVGGSNAKEGAWPWVVGLYYGGR 807



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 18/105 (17%)

Query: 859 AEKFQCEGSETH--LALCPIVQHPEDTCIHSREVGVVCSRYTDVRLVNGKSQCDGQVEIN 916
           A+ FQC+  E    + LC    H ED    S E   V       R  NG +  +G V   
Sbjct: 645 ADHFQCKNGECVPLVNLCDGHLHCEDG---SDEADCV-------RFFNGTTNNNGLVRFR 694

Query: 917 VLGHWGSLCDTHWDPEDARVLCRQLSCGTA------LSTTGGKYI 955
           +   W + C  +W  + +  +C+ L  G+        ST GG ++
Sbjct: 695 IQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFSTDGGPFV 739



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 27/129 (20%)

Query: 1011 LANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDA 1070
            L N+ D +L          C+     R  +G +   G V       W T C + W    +
Sbjct: 658  LVNLCDGHLHCEDGSDEADCV-----RFFNGTTNNNGLVRFRIQSIWHTACAENWTTQIS 712

Query: 1071 HVVCQKLGCGVAFNATVSAHFGEGSGPIWLDD------LNCTGMESHLWQCPSRGWGQH- 1123
            + VCQ LG G           G  S PI+  D      LN T  + HL   PS+   Q  
Sbjct: 713  NDVCQLLGLG----------SGNSSKPIFSTDGGPFVKLN-TAPDGHLILTPSQQCLQDS 761

Query: 1124 ----DCRHK 1128
                 C HK
Sbjct: 762  LIRLQCNHK 770



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 17/48 (35%), Positives = 22/48 (45%)

Query: 1244 DRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGS 1291
            D +R   G T  +G V       W T C ++W    +  VCQ LG GS
Sbjct: 676  DCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGS 723



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 22/125 (17%)

Query: 155 LRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNS---P 211
           +R  +G  + +G V  + Q  W T C + W    +  VC+ LG  S   S  + ++   P
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFSTDGGP 737

Query: 212 AVLRPIWLDDIL-------CQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDSSDLELRL 264
            V      D  L       C  + L    C H+  G                + D+  ++
Sbjct: 738 FVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKK------------LAAQDITPKI 785

Query: 265 VGGTN 269
           VGG+N
Sbjct: 786 VGGSN 790



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 7/57 (12%)

Query: 583 LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAS 639
           +R   G+   +G +    Q  W T C + W ++ +  VC        ++G+G GN+S
Sbjct: 678 VRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVC-------QLLGLGSGNSS 727



 Score = 31.6 bits (70), Expect = 5.8
 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%)

Query: 682 CSDASDME--LRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGS 735
           C D SD    +R   G++   G V   +Q      CA  W   I+  VC+ L  GS
Sbjct: 668 CEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGS 723


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 40.4 bits (93), Expect = 0.013
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 23/159 (14%)

Query: 553 WDCEHSGWGKHNC---------VHREDVIVTCS-GDATWGLRLVGGSNRCSGRLEVYFQG 602
           +DC     GK+ C         + R D +  C  G+  +    VGG N     L+V+   
Sbjct: 71  FDCS----GKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAV---LQVFTAA 123

Query: 603 RWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDG--DESDLW 660
            W T+C D W    A V C+QL  PS +    L   S+  G+   + VS D    +  + 
Sbjct: 124 SWKTMCSDDWKGHYANVACAQLGFPSYVSSDNL-RVSSLEGQFREEFVSIDHLLPDDKVT 182

Query: 661 SCRNSGWGNNDCSHSEDVGV---ICSDASDMELRLVGGS 696
           +  +S +    C+    V +    C        R+VGG+
Sbjct: 183 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGN 221



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 1/65 (1%)

Query: 28  CILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCK 87
           CI L+  C  +S     + E R V   G  +  ++V     W T+C D W    + V C 
Sbjct: 85  CIELIARCDGVSDCKDGEDEYRCVRVGGQ-NAVLQVFTAASWKTMCSDDWKGHYANVACA 143

Query: 88  QLGCP 92
           QLG P
Sbjct: 144 QLGFP 148



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 13/86 (15%)

Query: 331 CSGNESFLWDCRHSGTVNFDCLH---QNDVSVICSDGADLELRLADGSNNCSGRVEVRIH 387
           CSG     + CR S    F C+    + D    C DG D    +  G  N    ++V   
Sbjct: 73  CSGK----YRCRSS----FKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAV--LQVFTA 122

Query: 388 EQWWTICDQNWKNEQALVVCKQLGCP 413
             W T+C  +WK   A V C QLG P
Sbjct: 123 ASWKTMCSDDWKGHYANVACAQLGFP 148



 Score = 35.0 bits (79), Expect = 0.53
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 19/139 (13%)

Query: 176 WGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRP-----IWLDDILCQGNELA 230
           W T+C D W  + A V C QLG P S++SS  +   ++        + +D +L      A
Sbjct: 125 WKTMCSDDWKGHYANVACAQLGFP-SYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTA 183

Query: 231 LWNCRHRGWGNHDCSHNEDVTL---TCYDSSDLELRLVGGTNRCMG----RVELKIQGR- 282
           L    H  +    C+    VTL    C        R+VGG    +     +  L+ QG  
Sbjct: 184 L---HHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYH 240

Query: 283 --WGTVCHHKWNNAAADVV 299
              G+V    W   AA  V
Sbjct: 241 LCGGSVITPLWIITAAHCV 259



 Score = 34.3 bits (77), Expect = 0.90
 Identities = 14/37 (37%), Positives = 22/37 (59%)

Query: 1259 VEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAA 1295
            ++++ A SW T+C D W    A V C QLG  S +++
Sbjct: 117  LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSS 153


>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
           sapiens]
          Length = 344

 Score = 40.4 bits (93), Expect = 0.013
 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 23/159 (14%)

Query: 553 WDCEHSGWGKHNC---------VHREDVIVTCS-GDATWGLRLVGGSNRCSGRLEVYFQG 602
           +DC     GK+ C         + R D +  C  G+  +    VGG N     L+V+   
Sbjct: 71  FDCS----GKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAV---LQVFTAA 123

Query: 603 RWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDG--DESDLW 660
            W T+C D W    A V C+QL  PS +    L   S+  G+   + VS D    +  + 
Sbjct: 124 SWKTMCSDDWKGHYANVACAQLGFPSYVSSDNL-RVSSLEGQFREEFVSIDHLLPDDKVT 182

Query: 661 SCRNSGWGNNDCSHSEDVGV---ICSDASDMELRLVGGS 696
           +  +S +    C+    V +    C        R+VGG+
Sbjct: 183 ALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGN 221



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 1/65 (1%)

Query: 28  CILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCK 87
           CI L+  C  +S     + E R V   G  +  ++V     W T+C D W    + V C 
Sbjct: 85  CIELIARCDGVSDCKDGEDEYRCVRVGGQ-NAVLQVFTAASWKTMCSDDWKGHYANVACA 143

Query: 88  QLGCP 92
           QLG P
Sbjct: 144 QLGFP 148



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 13/86 (15%)

Query: 331 CSGNESFLWDCRHSGTVNFDCLH---QNDVSVICSDGADLELRLADGSNNCSGRVEVRIH 387
           CSG     + CR S    F C+    + D    C DG D    +  G  N    ++V   
Sbjct: 73  CSGK----YRCRSS----FKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAV--LQVFTA 122

Query: 388 EQWWTICDQNWKNEQALVVCKQLGCP 413
             W T+C  +WK   A V C QLG P
Sbjct: 123 ASWKTMCSDDWKGHYANVACAQLGFP 148



 Score = 35.0 bits (79), Expect = 0.53
 Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 19/139 (13%)

Query: 176 WGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRP-----IWLDDILCQGNELA 230
           W T+C D W  + A V C QLG P S++SS  +   ++        + +D +L      A
Sbjct: 125 WKTMCSDDWKGHYANVACAQLGFP-SYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTA 183

Query: 231 LWNCRHRGWGNHDCSHNEDVTL---TCYDSSDLELRLVGGTNRCMG----RVELKIQGR- 282
           L    H  +    C+    VTL    C        R+VGG    +     +  L+ QG  
Sbjct: 184 L---HHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYH 240

Query: 283 --WGTVCHHKWNNAAADVV 299
              G+V    W   AA  V
Sbjct: 241 LCGGSVITPLWIITAAHCV 259



 Score = 34.3 bits (77), Expect = 0.90
 Identities = 14/37 (37%), Positives = 22/37 (59%)

Query: 1259 VEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAA 1295
            ++++ A SW T+C D W    A V C QLG  S +++
Sbjct: 117  LQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSS 153


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score = 38.1 bits (87), Expect = 0.062
 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 19/144 (13%)

Query: 173 QERWGTICDDGWNLNTAAVVCRQLGCPSSFISS-GVVNSPAVLRPIWLDDILCQGNELAL 231
           ++ W  +C D WN N     CR +G  ++F SS G+V+       + L+     GN    
Sbjct: 202 RKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLN--TSAGNVDIY 259

Query: 232 WNCRHRGWGNHDCSHNEDVTLTCYD-----SSDLELRLVGGTNRCMG----RVELKIQG- 281
               H    +  CS    V+L C       +S  + R+VGG +   G    +V L +Q  
Sbjct: 260 KKLYH----SDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNV 315

Query: 282 --RWGTVCHHKWNNAAADVVCKQL 303
               G++   +W   AA  V K L
Sbjct: 316 HVCGGSIITPEWIVTAAHCVEKPL 339



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 1/70 (1%)

Query: 27  TCILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQ-WGTVCDDGWNTTASTVV 85
           TCI   N C  +S   G + E R V   GP         Q + W  VC D WN       
Sbjct: 162 TCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAA 221

Query: 86  CKQLGCPFSF 95
           C+ +G   +F
Sbjct: 222 CRDMGYKNNF 231


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 38.1 bits (87), Expect = 0.062
 Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 19/144 (13%)

Query: 173 QERWGTICDDGWNLNTAAVVCRQLGCPSSFISS-GVVNSPAVLRPIWLDDILCQGNELAL 231
           ++ W  +C D WN N     CR +G  ++F SS G+V+       + L+     GN    
Sbjct: 165 RKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLN--TSAGNVDIY 222

Query: 232 WNCRHRGWGNHDCSHNEDVTLTCYD-----SSDLELRLVGGTNRCMG----RVELKIQG- 281
               H    +  CS    V+L C       +S  + R+VGG +   G    +V L +Q  
Sbjct: 223 KKLYH----SDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNV 278

Query: 282 --RWGTVCHHKWNNAAADVVCKQL 303
               G++   +W   AA  V K L
Sbjct: 279 HVCGGSIITPEWIVTAAHCVEKPL 302



 Score = 31.2 bits (69), Expect = 7.6
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 1/70 (1%)

Query: 27  TCILLLNSCFLISSFNGTDLELRLVNGDGPCSGTVEVKFQGQ-WGTVCDDGWNTTASTVV 85
           TCI   N C  +S   G + E R V   GP         Q + W  VC D WN       
Sbjct: 125 TCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAA 184

Query: 86  CKQLGCPFSF 95
           C+ +G   +F
Sbjct: 185 CRDMGYKNNF 194


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.469 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,458,672
Number of Sequences: 37866
Number of extensions: 3129223
Number of successful extensions: 7642
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 5650
Number of HSP's gapped (non-prelim): 540
length of query: 1453
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1338
effective length of database: 13,892,928
effective search space: 18588737664
effective search space used: 18588737664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.