Guide to the Human Genome
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Name: TMPRSS2 Sequence: fasta or formatted (529aa) NCBI GI: 227499990
Description:

transmembrane protease, serine 2 isoform 1

Referenced in:

Serine Proteases

Other entries for this name:
alt prot [492aa] transmembrane protease, serine 2 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.0         37           2
 C cysteine            4.3         23           1
 D aspartate           4.0         21           2
 E glutamate           3.8         20           2
 F phenylalanine       2.1         11           1
 G glycine             9.1         48           2
 H histidine           2.3         12           1
 I isoleucine          4.3         23           2
 K lysine              4.7         25           2
 L leucine             6.8         36           2
 M methionine          2.3         12           2
 N asparagine          6.2         33           2
 P proline             7.2         38           2
 Q glutamine           4.2         22           1
 R arginine            3.2         17           1
 S serine              9.1         48           2
 T threonine           4.7         25           1
 V valine              7.4         39           2
 W tryptophan          2.8         15           2
 Y tyrosine            4.5         24           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   transmembrane protease, serine 2 isoform 1 
TMPRSS2               0.930   transmembrane protease, serine 2 isoform 2 
TMPRSS3               0.279   transmembrane protease, serine 3 isoform 1 
TMPRSS13              0.228   transmembrane protease, serine 13 
TMPRSS4               0.206   transmembrane protease, serine 4 isoform 3 
TMPRSS4               0.206   transmembrane protease, serine 4 isoform 1 
TMPRSS5               0.203   transmembrane protease, serine 5 
PRSS7                 0.201   enterokinase precursor 
CORIN                 0.182   corin 
KLKB1                 0.174   plasma kallikrein B1 precursor 
HPN                   0.169   hepsin 
HPN                   0.169   hepsin 
TMPRSS11F             0.166   transmembrane protease, serine 11F 
TMPRSS11D             0.162   transmembrane protease, serine 11D 
F11                   0.161   coagulation factor XI precursor 
ST14                  0.160   matriptase 
TMPRSS7               0.153   transmembrane protease, serine 7 
TMPRSS6               0.153   transmembrane protease, serine 6 
TMPRSS11E             0.150   transmembrane protease, serine 11E 
TMPRSS11E2            0.150   transmembrane protease, serine 11E2 
TMPRSS11B             0.150   transmembrane protease, serine 11B 
ACR                   0.150   acrosin precursor 
TMPRSS9               0.149   transmembrane protease, serine 9 
OVCH1                 0.149   ovochymase 1 
TMPRSS3               0.146   transmembrane protease, serine 3 isoform 3 
TMPRSS11A             0.143   transmembrane protease, serine 11A isoform 2 
TMPRSS11A             0.143   transmembrane protease, serine 11A isoform 1 
PRSS21                0.141   testisin isoform 2 
PRSS27                0.141   marapsin 
PRSS33                0.141   protease, serine, 33 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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