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Search of human proteins with 4758284
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
(984 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 1994 0.0
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 1518 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 1515 0.0
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 1408 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 1164 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 1139 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 1136 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 1130 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1115 0.0
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 1084 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 1070 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 1039 0.0
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 932 0.0
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 885 0.0
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 822 0.0
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 738 0.0
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 556 e-158
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 451 e-126
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 278 2e-74
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens] 228 2e-59
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 227 4e-59
gi|119395736 insulin receptor isoform Long precursor [Homo sapiens] 227 4e-59
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 227 5e-59
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens] 225 1e-58
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens] 225 1e-58
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens] 224 2e-58
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 223 5e-58
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 223 5e-58
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens] 222 1e-57
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens] 221 3e-57
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 1994 bits (5166), Expect = 0.0
Identities = 984/984 (100%), Positives = 984/984 (100%)
Query: 1 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV 60
MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV
Sbjct: 1 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQV 60
Query: 61 CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV 120
CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV
Sbjct: 61 CNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSV 120
Query: 121 IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY 180
IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY
Sbjct: 121 IATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDY 180
Query: 181 GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC 240
GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC
Sbjct: 181 GACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYC 240
Query: 241 NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI 300
NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI
Sbjct: 241 NGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPI 300
Query: 301 CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC 360
CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC
Sbjct: 301 CTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIIC 360
Query: 361 KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP 420
KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP
Sbjct: 361 KKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPP 420
Query: 421 QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN 480
QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN
Sbjct: 421 QHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFN 480
Query: 481 SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP 540
SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP
Sbjct: 481 SSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLP 540
Query: 541 LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY 600
LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY
Sbjct: 541 LIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTY 600
Query: 601 EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK 660
EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK
Sbjct: 601 EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK 660
Query: 661 QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ 720
QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ
Sbjct: 661 QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ 720
Query: 721 LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS 780
LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS
Sbjct: 721 LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS 780
Query: 781 SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD 840
SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD
Sbjct: 781 SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD 840
Query: 841 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ
Sbjct: 841 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
Query: 901 PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG 960
PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG
Sbjct: 901 PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG 960
Query: 961 HQKKILNSIHSMRVQISQSPTAMA 984
HQKKILNSIHSMRVQISQSPTAMA
Sbjct: 961 HQKKILNSIHSMRVQISQSPTAMA 984
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 1518 bits (3929), Expect = 0.0
Identities = 717/972 (73%), Positives = 849/972 (87%), Gaps = 2/972 (0%)
Query: 9 LLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQ 68
LLL +AA+EETLMD+ TATAELGW +P SGWEEVSGYDEN+NTIRTYQVCNVFE +Q
Sbjct: 10 LLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQ 69
Query: 69 NNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAF 128
NNWL T FI RRGAHRI+ EM+F+VRDCSS+P+VPGSCKETFNLYYYE D ATK
Sbjct: 70 NNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPN 129
Query: 129 WSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLS 188
W E P++KVDTIAADESFSQVD GGR+MK+NTEVRSFGP++R+GFYLAFQDYG CMSL++
Sbjct: 130 WMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIA 189
Query: 189 VRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMV 248
VRVF++KCP I+QN A+F ET++GAESTSLV ARG+CI NAEEVDVPIKLYCNGDGEW+V
Sbjct: 190 VRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLV 249
Query: 249 PIGRCTCKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGY 307
PIGRC CK G+E EN C+ CP+GTFKA+Q E C+HCP NSR+ +E + C CR GY
Sbjct: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 308 YRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADR 367
YRAD DP ++ CT++PS P+ VIS VNETS++LEW PPR++GGR+D+ YNIICK C + R
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 368 RSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNI 427
+C+RC DNV++ PRQLGLTE R+ IS L AHT YTF+IQA+NGV+ +SPF PQ SVNI
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
Query: 428 TTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQ 487
TTNQAAPS V IMHQVS T+ SITLSW QP+QPNG+ILDYE++YYEKE +E+N++ +S
Sbjct: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSP 489
Query: 488 TNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAA 547
TNT + GL+ G +YV QVRARTVAGYG++SGKM FQT+T+ +Y++ ++E+LPLI GS+A
Sbjct: 490 TNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSA 549
Query: 548 AGVVFVVSLVAISIVCSRKRAYSK-EAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEA 606
AG+VF++++V I+IVC+R+R + + ++ Y+DKLQHY++G +PGMKIYIDPFTYEDPNEA
Sbjct: 550 AGLVFLIAVVVIAIVCNRRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEA 609
Query: 607 VREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFL 666
VREFAKEID+S VKIE+VIGAGEFGEV G LKLPGKREI+VAIKTLK+GY+EKQRRDFL
Sbjct: 610 VREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFL 669
Query: 667 SEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLR 726
SEASIMGQFDHPN+I LEGVVTKS PVMIITEFMENG+LDSFLRQNDGQFTVIQLVGMLR
Sbjct: 670 SEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLR 729
Query: 727 GIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKI 786
GIAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DDTSDPTYTS+LGGKI
Sbjct: 730 GIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKI 789
Query: 787 PVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPP 846
P+RWTAPEAI YRKFTSASDVWSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPPP
Sbjct: 790 PIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPP 849
Query: 847 MDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRS 906
MDCP+ALHQLMLDCWQKDRN RP+F +IVNTLDKMIRNP SLK +A +++ + PLLDR+
Sbjct: 850 MDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRT 909
Query: 907 IPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKIL 966
IPD+T+F TVD+WL AIKM QY++SF AGFTS +V+QM ED+LR+G+TLAGHQKKIL
Sbjct: 910 IPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKIL 969
Query: 967 NSIHSMRVQISQ 978
NSI MR Q++Q
Sbjct: 970 NSIQVMRAQMNQ 981
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 1515 bits (3923), Expect = 0.0
Identities = 716/971 (73%), Positives = 846/971 (87%), Gaps = 1/971 (0%)
Query: 9 LLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQ 68
LLL +AA+EETLMD+ TATAELGW +P SGWEEVSGYDEN+NTIRTYQVCNVFE +Q
Sbjct: 10 LLLLPLLAAVEETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQ 69
Query: 69 NNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAF 128
NNWL T FI RRGAHRI+ EM+F+VRDCSS+P+VPGSCKETFNLYYYE D ATK
Sbjct: 70 NNWLRTKFIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPN 129
Query: 129 WSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLS 188
W E P++KVDTIAADESFSQVD GGR+MK+NTEVRSFGP++R+GFYLAFQDYG CMSL++
Sbjct: 130 WMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIA 189
Query: 189 VRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMV 248
VRVF++KCP I+QN A+F ET++GAESTSLV ARG+CI NAEEVDVPIKLYCNGDGEW+V
Sbjct: 190 VRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLV 249
Query: 249 PIGRCTCKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGY 307
PIGRC CK G+E EN C+ CP+GTFKA+Q E C+HCP NSR+ +E + C CR GY
Sbjct: 250 PIGRCMCKAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGY 309
Query: 308 YRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADR 367
YRAD DP ++ CT++PS P+ VIS VNETS++LEW PPR++GGR+D+ YNIICK C + R
Sbjct: 310 YRADLDPLDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGR 369
Query: 368 RSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNI 427
+C+RC DNV++ PRQLGLTE R+ IS L AHT YTF+IQA+NGV+ +SPF PQ SVNI
Sbjct: 370 GACTRCGDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNI 429
Query: 428 TTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQ 487
TTNQAAPS V IMHQVS T+ SITLSW QP+QPNG+ILDYE++YYEKE +E+N++ +S
Sbjct: 430 TTNQAAPSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSP 489
Query: 488 TNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAA 547
TNT + GL+ G +YV QVRARTVAGYG++SGKM FQT+T+ +Y++ ++E+LPLI GS+A
Sbjct: 490 TNTVTVQGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSA 549
Query: 548 AGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAV 607
AG+VF++++V I+IVC+R+ ++ Y+DKLQHY++G +PGMKIYIDPFTYEDPNEAV
Sbjct: 550 AGLVFLIAVVVIAIVCNRRGFERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAV 609
Query: 608 REFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLS 667
REFAKEID+S VKIE+VIGAGEFGEV G LKLPGKREI+VAIKTLK+GY+EKQRRDFLS
Sbjct: 610 REFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLS 669
Query: 668 EASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRG 727
EASIMGQFDHPN+I LEGVVTKS PVMIITEFMENG+LDSFLRQNDGQFTVIQLVGMLRG
Sbjct: 670 EASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRG 729
Query: 728 IAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIP 787
IAAGMKYLA+MNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DDTSDPTYTS+LGGKIP
Sbjct: 730 IAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIP 789
Query: 788 VRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPM 847
+RWTAPEAI YRKFTSASDVWSYGIVMWEVMS+GERPYWDM+NQDVINAIEQDYRLPPPM
Sbjct: 790 IRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPM 849
Query: 848 DCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSI 907
DCP+ALHQLMLDCWQKDRN RP+F +IVNTLDKMIRNP SLK +A +++ + PLLDR+I
Sbjct: 850 DCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTI 909
Query: 908 PDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILN 967
PD+T+F TVD+WL AIKM QY++SF AGFTS +V+QM ED+LR+G+TLAGHQKKILN
Sbjct: 910 PDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILN 969
Query: 968 SIHSMRVQISQ 978
SI MR Q++Q
Sbjct: 970 SIQVMRAQMNQ 980
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 1408 bits (3645), Expect = 0.0
Identities = 690/978 (70%), Positives = 811/978 (82%), Gaps = 14/978 (1%)
Query: 6 LLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFE 65
L LLLL + A+EETLMDT+ T+EL WT++P SGWEEVSGYDE +N IRTYQVCNV E
Sbjct: 26 LPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRE 85
Query: 66 PNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKK 125
+QNNWL T FI RR R+Y E++FTVRDC+S+PN+PGSCKETFNL+YYE DS +A+
Sbjct: 86 SSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASAS 145
Query: 126 SAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMS 185
S FW E PY+KVDTIA DESFS++D G +VNT+VRSFGPL++ GFYLAFQD GACMS
Sbjct: 146 SPFWMENPYVKVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMS 201
Query: 186 LLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGE 245
L+SVR F+KKC S FA+FPET+TGAE TSLVIA GTCIPNA EV VP+KLYCNGDGE
Sbjct: 202 LISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGE 261
Query: 246 WMVPIGRCTCKPGYEPENSVA-CKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCR 304
WMVP+G CTC G+EP + C+ CP G++KA Q C CP NSR+ + A+ ICTC
Sbjct: 262 WMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCH 321
Query: 305 TGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCR 364
+YRAD D + ACT+VPS PR VIS VNETS+ILEW PR+ GGRDD+ YN+ICKKC
Sbjct: 322 NNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCH 381
Query: 365 A--DRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQH 422
+CSRCDDNVEFVPRQLGLTE RV IS L AHT YTF++QA+NGVS KSP PP++
Sbjct: 382 GAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRY 441
Query: 423 VSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSS 482
+VNITTNQAAPS VP + S++ S+TLSW PE+PNG+ILDYE++Y+EK +E +S
Sbjct: 442 AAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEK--SEGIAS 499
Query: 483 MARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTD-DDYKSELREQLPL 541
SQ N+ ++DGLRP YVVQVRARTVAGYG++S F+T ++ +L+EQLPL
Sbjct: 500 TVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPL 559
Query: 542 IAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYE 601
I GSA AG+VFVV++V I+IVC RK+ + ++ Y++KLQ Y +PGMK+YIDPFTYE
Sbjct: 560 IVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYI----APGMKVYIDPFTYE 615
Query: 602 DPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQ 661
DPNEAVREFAKEIDVS VKIEEVIGAGEFGEV +GRLK PG+RE++VAIKTLK GY+E+Q
Sbjct: 616 DPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQ 675
Query: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721
RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMI+TEFMEN ALDSFLR NDGQFTVIQL
Sbjct: 676 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQL 735
Query: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781
VGMLRGIAAGMKYL+EMNYVHRDLAARNILVNSNLVCKVSDFGLSR+L+DD SDPTYTSS
Sbjct: 736 VGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795
Query: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841
LGGKIP+RWTAPEAIAYRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQDVINA+EQDY
Sbjct: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDY 855
Query: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQP 901
RLPPPMDCP ALHQLMLDCW +DRN RP+F++IVNTLDK+IRN ASLK +A+ + SQP
Sbjct: 856 RLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQP 915
Query: 902 LLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGH 961
LLDR++PD+T FTTV DWL AIKM +Y++SF++AGF S LV QMT+EDLLRIG+TLAGH
Sbjct: 916 LLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGH 975
Query: 962 QKKILNSIHSMRVQISQS 979
QKKIL+SI MR+Q++Q+
Sbjct: 976 QKKILSSIQDMRLQMNQT 993
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 1164 bits (3010), Expect = 0.0
Identities = 578/964 (59%), Positives = 717/964 (74%), Gaps = 15/964 (1%)
Query: 17 AMEETLMDTRTATAELGWTANPASG-WEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTT 75
A E TL+D+R+ ELGW A+P G WEEVS DE IRTYQVCNV EP+QNNWL T
Sbjct: 28 ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
Query: 76 FINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYL 135
+I R GA R+Y E++FT+RDC+SLP V G+CKETFNLYYYE+D+ K F E ++
Sbjct: 88 WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDN----DKERFIRENQFV 143
Query: 136 KVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKK 195
K+DTIAADESF+QVD G R+MK+NTE+R GPL++ GFYLAFQD GAC++L+SVRVF+KK
Sbjct: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203
Query: 196 CPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTC 255
CP V+N A FP+T+TGA+++SLV RG+C+ N+EE DVP K+YC DGEW+VPIG C C
Sbjct: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262
Query: 256 KPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPP 315
G+E E S C+AC G +KA C+ CP +S S E + CTC G++RAD D
Sbjct: 263 NAGHE-ERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAA 321
Query: 316 EVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRA-DRRSCSRCD 374
+ CT PS P N+IS VNETS+ LEW P+ TGGR D++YN++CKKC A D C C
Sbjct: 322 SMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCG 381
Query: 375 DNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAP 434
V + P+Q GL +VSI+ L AHT YTF+I A+NGVS +P P Q VSV +TTNQAAP
Sbjct: 382 SGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAP 441
Query: 435 STVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARID 494
S++ ++ T S+ L+W +P++PNG+IL+YE++YYEK+ NE + + R+ I
Sbjct: 442 SSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIK 501
Query: 495 GLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVV 554
GL P YV VRART AGYG FS + T T ++ S + VV VV
Sbjct: 502 GLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVV 561
Query: 555 SLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEI 614
L+A ++ R+ YSK +D+ +H + G ++ Y+DPFTYEDPN+AVREFAKEI
Sbjct: 562 ILIAAFVISRRRSKYSKAKQEADEEKHLNQG-----VRTYVDPFTYEDPNQAVREFAKEI 616
Query: 615 DVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQ 674
D S +KIE+VIG GEFGEV GRLK+PGKREI VAIKTLKAGY++KQRRDFLSEASIMGQ
Sbjct: 617 DASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQ 676
Query: 675 FDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKY 734
FDHPNII LEGVVTK +PVMIITE+MENG+LD+FLR+NDG+FTVIQLVGMLRGI +GMKY
Sbjct: 677 FDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKY 736
Query: 735 LAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPE 794
L++M+YVHRDLAARNILVNSNLVCKVSDFG+SR L+DD + YT+ GGKIP+RWTAPE
Sbjct: 737 LSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIRWTAPE 794
Query: 795 AIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALH 854
AIAYRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ YRLPPPMDCP ALH
Sbjct: 795 AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854
Query: 855 QLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFT 914
QLMLDCWQK+R+ RP+F +IVN LDK+IRNP SLK T ++ P+ LLD S P+F+A
Sbjct: 855 QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVV 914
Query: 915 TVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRV 974
+V DWL AIKM +Y+D+F AG+T+L+ V + EDL RIGIT HQ KIL+S+ +MR
Sbjct: 915 SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRT 974
Query: 975 QISQ 978
Q+ Q
Sbjct: 975 QMQQ 978
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
Length = 1015
Score = 1139 bits (2945), Expect = 0.0
Identities = 563/976 (57%), Positives = 724/976 (74%), Gaps = 19/976 (1%)
Query: 9 LLLASAVAAM------EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCN 62
LLL +A+ + E L+D+RT +LGW A P +GWEE+ DEN I TYQVC
Sbjct: 44 LLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCK 103
Query: 63 VFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIA 122
V E NQNNWLLT++I+ GA RI+ E++FT+RDC+SLP G+CKETFN+YY+E+D
Sbjct: 104 VMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD--- 160
Query: 123 TKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGA 182
+ E Y+K+DTIAADESF+++D G R+MK+NTEVR GPL++ GFYLAFQD GA
Sbjct: 161 -QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
Query: 183 CMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNG 242
C++L+SVRV++KKCPS+V++ AVFP+T+TGA+S+ L+ G+C+ N D P K++C+
Sbjct: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSA 278
Query: 243 DGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICT 302
+GEW+VPIG+C CK GYE +N C+ C G FKAS + C CP +S + EAS C
Sbjct: 279 EGEWLVPIGKCMCKAGYEEKNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337
Query: 303 CRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKK 362
C Y+R + DPP +ACT PS PRN IS VNETS+ LEW PP +TGGR DV+Y I CKK
Sbjct: 338 CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397
Query: 363 CRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQH 422
C + C C +V ++PRQ GL V + L AHT YTF+I+A+NGVS SP Q+
Sbjct: 398 CNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQY 457
Query: 423 VSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSS 482
VSVN+TTNQAAPS V + + SI+LSW +P++PNGIIL+YEI+Y+EK+ E + +
Sbjct: 458 VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYT 516
Query: 483 MARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLI 542
+ +S+ T +GL+P VYV Q+RART AGYG FS + F+T T S + Q+P+I
Sbjct: 517 IIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVI 575
Query: 543 AGSAAAGVVFVVSLVAISIVCSRKRAYSK--EAVYSDKLQHYSTGRGSPGMKIYIDPFTY 600
A S GV+ + ++ + ++ R+ YSK + +K+ ++ PG++ YIDP TY
Sbjct: 576 AVSVTVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTY 634
Query: 601 EDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEK 660
EDPN+AV EFAKEI+ S + IE VIGAGEFGEV GRLKLPGKRE+ VAIKTLK GY+EK
Sbjct: 635 EDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEK 694
Query: 661 QRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQ 720
QRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+MENG+LD+FL++NDGQFTVIQ
Sbjct: 695 QRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQ 754
Query: 721 LVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTS 780
LVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCKVSDFGLSR L+DD + YT+
Sbjct: 755 LVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTT 813
Query: 781 SLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD 840
GGKIP+RWTAPEAIA+RKFTSASDVWSYGIVMWEV+S+GERPYW+M+NQDVI A+E+
Sbjct: 814 R-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEG 872
Query: 841 YRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQ 900
YRLP PMDCPAAL+QLMLDCWQK+RNSRP+F EIVN LDK+IRNP+SLKT+ + S
Sbjct: 873 YRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSN 932
Query: 901 PLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAG 960
L + S A+ +V +WL AIKM +Y + F+ G++S+ V Q+T EDL R+G+TL G
Sbjct: 933 LLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVG 992
Query: 961 HQKKILNSIHSMRVQI 976
HQKKI+NS+ M+VQ+
Sbjct: 993 HQKKIMNSLQEMKVQL 1008
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 1136 bits (2939), Expect = 0.0
Identities = 567/985 (57%), Positives = 722/985 (73%), Gaps = 20/985 (2%)
Query: 3 LDYLLLLLLA---SAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQ 59
L Y+ LL A A AA E L+D++ EL W ++P +GWEE+SG DEN IRTYQ
Sbjct: 13 LCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQ 72
Query: 60 VCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDS 119
VC V EPNQNNWL T +I++ A RI+ E++FT+RDC+SLP V G+CKETFNLYYYETD
Sbjct: 73 VCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETD- 131
Query: 120 VIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQD 179
T ++ E Y+K+DTIAADESF+Q D G R MK+NTEVR GPL++ GFYLAFQD
Sbjct: 132 -YDTGRNI--RENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQD 188
Query: 180 YGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEE-VDVPIKL 238
GAC++L+SV+V++KKC SI++N A+FP+T+TG+E +SLV RGTC+ +AEE + ++
Sbjct: 189 VGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRM 248
Query: 239 YCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEAS 298
+C+ +GEW+VPIG+C CK GY+ + C+ C G +K+S + CS CP++S S E S
Sbjct: 249 HCSAEGEWLVPIGKCICKAGYQQKGDT-CEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGS 307
Query: 299 PICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNI 358
C C GYYRA DPP VACT PS P+N+I +N+T++ LEW PP + GGR+DVTY I
Sbjct: 308 SRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRI 367
Query: 359 ICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPF 418
+CK+C ++ C C N+ ++P+Q GL + V++ L AH YTF+++A+NGVS S
Sbjct: 368 LCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRS 427
Query: 419 PPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNE 478
+V+ITT QAAPS V + + RS+ LSW +PE PNG+I +YEI+YYEK+ E
Sbjct: 428 QRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRE 487
Query: 479 FNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYK------ 532
S ++++ +A I+ L+PG VYV Q+RA T AGYG +S ++ TL + K
Sbjct: 488 RTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATA 547
Query: 533 -SELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGM 591
S + + +IA A AG + +V +V I+ R YSK D+ ++ PG
Sbjct: 548 VSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHFK--FPGT 605
Query: 592 KIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIK 651
K YIDP TYEDPN AV +FAKE+D S +KIE VIGAGEFGEV GRLKLPGKR++ VAIK
Sbjct: 606 KTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIK 665
Query: 652 TLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQ 711
TLK GY+EKQRRDFL EASIMGQFDHPN++ LEGVVT+ +PVMI+ EFMENGALD+FLR+
Sbjct: 666 TLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRK 725
Query: 712 NDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQD 771
+DGQFTVIQLVGMLRGIAAGM+YLA+M YVHRDLAARNILVNSNLVCKVSDFGLSR ++D
Sbjct: 726 HDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIED 785
Query: 772 DTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQ 831
D + YT++ GGKIPVRWTAPEAI YRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQ
Sbjct: 786 D-PEAVYTTT-GGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQ 843
Query: 832 DVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTV 891
DVI AIE+ YRLP PMDCPA LHQLMLDCWQK+R RP+F +IV LDKMIRNP SLKT
Sbjct: 844 DVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTP 903
Query: 892 ATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDL 951
+ P PLLD++ PDFT F +V +WL AIKM +Y+D+F AG+ SL+ V +MT ED+
Sbjct: 904 LGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDV 963
Query: 952 LRIGITLAGHQKKILNSIHSMRVQI 976
+ +GITL GHQKKI++SI +MR Q+
Sbjct: 964 MSLGITLVGHQKKIMSSIQTMRAQM 988
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
Length = 1037
Score = 1130 bits (2924), Expect = 0.0
Identities = 569/997 (57%), Positives = 724/997 (72%), Gaps = 39/997 (3%)
Query: 9 LLLASAVAAM------EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCN 62
LLL +A+ + E L+D+RT +LGW A P +GWEE+ DEN I TYQVC
Sbjct: 44 LLLCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCK 103
Query: 63 VFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIA 122
V E NQNNWLLT++I+ GA RI+ E++FT+RDC+SLP G+CKETFN+YY+E+D
Sbjct: 104 VMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD--- 160
Query: 123 TKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGA 182
+ E Y+K+DTIAADESF+++D G R+MK+NTEVR GPL++ GFYLAFQD GA
Sbjct: 161 -QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGA 219
Query: 183 CMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNG 242
C++L+SVRV++KKCPS+V++ AVFP+T+TGA+S+ L+ G+C+ N D P K++C+
Sbjct: 220 CIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCV-NHSVTDEPPKMHCSA 278
Query: 243 DGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICT 302
+GEW+VPIG+C CK GYE +N C+ C G FKAS + C CP +S + EAS C
Sbjct: 279 EGEWLVPIGKCMCKAGYEEKNGT-CQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337
Query: 303 CRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKK 362
C Y+R + DPP +ACT PS PRN IS VNETS+ LEW PP +TGGR DV+Y I CKK
Sbjct: 338 CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397
Query: 363 CRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQH 422
C + C C +V ++PRQ GL V + L AHT YTF+I+A+NGVS SP Q+
Sbjct: 398 CNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQY 457
Query: 423 VSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSS 482
VSVN+TTNQAAPS V + + SI+LSW +P++PNGIIL+YEI+Y+EK+ E + +
Sbjct: 458 VSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSYT 516
Query: 483 MARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLI 542
+ +S+ T +GL+P VYV Q+RART AGYG FS + F+T T S + Q+P+I
Sbjct: 517 IIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFET-TPVFAASSDQSQIPVI 575
Query: 543 AGSAAAGVVFVVSLVAISIV-----CSRKRAYSKEAV----------YSDKLQ------- 580
A S GV+ + ++ + + C RA S AV YS Q
Sbjct: 576 AVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKM 635
Query: 581 HYSTGRGS-PGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLK 639
H+ G PG++ YIDP TYEDPN+AV EFAKEI+ S + IE VIGAGEFGEV GRLK
Sbjct: 636 HFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLK 695
Query: 640 LPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEF 699
LPGKRE+ VAIKTLK GY+EKQRRDFL EASIMGQFDHPNII LEGVVTKS+PVMI+TE+
Sbjct: 696 LPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEY 755
Query: 700 MENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCK 759
MENG+LD+FL++NDGQFTVIQLVGMLRGI+AGMKYL++M YVHRDLAARNIL+NSNLVCK
Sbjct: 756 MENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCK 815
Query: 760 VSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
VSDFGLSR L+DD + YT+ GGKIP+RWTAPEAIA+RKFTSASDVWSYGIVMWEV+S
Sbjct: 816 VSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVS 873
Query: 820 FGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLD 879
+GERPYW+M+NQDVI A+E+ YRLP PMDCPAAL+QLMLDCWQK+RNSRP+F EIVN LD
Sbjct: 874 YGERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLD 933
Query: 880 KMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTS 939
K+IRNP+SLKT+ + S L + S A+ +V +WL AIKM +Y + F+ G++S
Sbjct: 934 KLIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSS 993
Query: 940 LQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQI 976
+ V Q+T EDL R+G+TL GHQKKI+NS+ M+VQ+
Sbjct: 994 MDAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 1115 bits (2885), Expect = 0.0
Identities = 543/963 (56%), Positives = 706/963 (73%), Gaps = 12/963 (1%)
Query: 19 EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFIN 78
E L+D++T ELGW + P+ GWEE+SG DE+ IRTYQVCNV + +QNNWL T ++
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
Query: 79 RRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVD 138
R A +IY E++FT+RDC+S+P V G+CKETFNLYY E+D K + E + K+D
Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
Query: 139 TIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPS 198
TIAADESF+Q+D G R++K+NTE+R GP+ + GFYLAFQD GAC++L+SVRV+FKKCP
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
Query: 199 IVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPG 258
V+N A+FP+T+ +S SLV RG+C+ N++E D P ++YC+ +GEW+VPIG+C+C G
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
Query: 259 YEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVA 318
YE E C+AC G +KA C+ CP +S + + S C C Y+RAD DPP +A
Sbjct: 263 YE-ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
Query: 319 CTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVE 378
CT PS PRNVIS +NETS+IL+W P +TGGR DVT+NIICKKC + + C C NV
Sbjct: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
Query: 379 FVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP 438
F+PRQ GLT V+++ L AHT YTF+I A+NGVS S P Q +V+ITTNQAAPS V
Sbjct: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
Query: 439 IMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRP 498
+ + + SI+LSW +PE PNGIILDYE++YYEK+ E + ++ R++ I L+P
Sbjct: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
Query: 499 GMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVA 558
+YV Q+RART AGYG S K F+T D S Q+ +IA SAA ++ + V
Sbjct: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESSQVVMIAISAAVAIILLT--VV 559
Query: 559 ISIVCSRKRAYSKEAVYSDKLQHYSTGRGS-PGMKIYIDPFTYEDPNEAVREFAKEIDVS 617
I ++ R Y + +K H+ G PG++ Y+DP TYEDP +AV EFAKE+D +
Sbjct: 560 IYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619
Query: 618 FVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDH 677
+ I++V+GAGEFGEV GRLKLP K+EI VAIKTLK GY+EKQRRDFL EASIMGQFDH
Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679
Query: 678 PNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAE 737
PNIIRLEGVVTKS+PVMI+TE+MENG+LDSFLR++D QFTVIQLVGMLRGIA+GMKYL++
Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739
Query: 738 MNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIA 797
M YVHRDLAARNIL+NSNLVCKVSDFGLSR L+DD + YT+ GGKIP+RWT+PEAIA
Sbjct: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDD-PEAAYTTR-GGKIPIRWTSPEAIA 797
Query: 798 YRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLM 857
YRKFTSASDVWSYGIV+WEVMS+GERPYW+MSNQDVI A+++ YRLPPPMDCPAAL+QLM
Sbjct: 798 YRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLM 857
Query: 858 LDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVD 917
LDCWQKDRN+RP+F +IV+ LDK+IRNP SLK + + A PS LLD+S D T F T
Sbjct: 858 LDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTG 917
Query: 918 DWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQIS 977
DWL+ + ++ F ++S + +++++D+ ++G+T+ G QKKI++SI ++ Q
Sbjct: 918 DWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQSK 977
Query: 978 QSP 980
P
Sbjct: 978 NGP 980
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 1084 bits (2803), Expect = 0.0
Identities = 555/980 (56%), Positives = 701/980 (71%), Gaps = 16/980 (1%)
Query: 3 LDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPA--SGWEEVSGYDENLNTIRTYQV 60
++ +LL AS AA+EETL++T+ TA+L W P WEE+SG DE +++RTY+V
Sbjct: 1 MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV 60
Query: 61 CNVFE-PNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDS 119
C+V P Q +WL T ++ RRGA +Y +RFT+ +C SLP SCKETF ++YYE+D+
Sbjct: 61 CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA 120
Query: 120 VIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQD 179
AT + W E PY+KVDT+AA+ + KVN + GPL++ GFYLAFQD
Sbjct: 121 DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD 180
Query: 180 YGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPI-KL 238
GACM+LLS+ +F+KKC + N FPET+ +V G+C+ +A P L
Sbjct: 181 QGACMALLSLHLFYKKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSL 237
Query: 239 YCNGDGEWMV-PIGRCTCKPGYEP-ENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAE 296
YC DG+W P+ C+C PG+E E + C+AC GTFK C CP+NS S
Sbjct: 238 YCREDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTI 297
Query: 297 ASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTY 356
S +C CR GY+RA DP CT+ PS PR+V+S +N +S+ LEW P E+GGR+D+TY
Sbjct: 298 GSAVCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTY 357
Query: 357 NIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKS 416
+ C++CR SC+ C ++ F P L E V + L YTF++ A+NGVSS +
Sbjct: 358 ALRCRECRPGG-SCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLA 416
Query: 417 PFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEH 476
P VN+TT++ P V + ++ S++L+W P P+G +LDYE++Y+EK
Sbjct: 417 TGPVPFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGA 476
Query: 477 NEFNS-SMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSEL 535
+S ++ N A + GL+ G Y+VQVRAR+ AGYG F + QT D+
Sbjct: 477 EGPSSVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDES--EGW 534
Query: 536 REQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYI 595
REQL LIAG+A GVV V+ ++ ++++C RK++ +EA YSDK Y G G+ K+YI
Sbjct: 535 REQLALIAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGT---KVYI 591
Query: 596 DPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKA 655
DPFTYEDPNEAVREFAKEIDVS+VKIEEVIGAGEFGEV +GRLK PGK+E VAIKTLK
Sbjct: 592 DPFTYEDPNEAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKG 651
Query: 656 GYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQ 715
GY+E+QRR+FLSEASIMGQF+HPNIIRLEGVVT S PVMI+TEFMENGALDSFLR NDGQ
Sbjct: 652 GYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQ 711
Query: 716 FTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSD 775
FTVIQLVGMLRGIA+GM+YLAEM+YVHRDLAARNILVNSNLVCKVSDFGLSR+L++++SD
Sbjct: 712 FTVIQLVGMLRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSD 771
Query: 776 PTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVIN 835
PTYTSSLGGKIP+RWTAPEAIA+RKFTSASD WSYGIVMWEVMSFGERPYWDMSNQDVIN
Sbjct: 772 PTYTSSLGGKIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVIN 831
Query: 836 AIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATIT 895
AIEQDYRLPPP DCP +LHQLMLDCWQKDRN+RPRF ++V+ LDKMIRNPASLK VA
Sbjct: 832 AIEQDYRLPPPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVAREN 891
Query: 896 AVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIG 955
S PLLD+ P ++AF +V +WL AIKM +Y +SF AGF S +LV+Q+++EDLLRIG
Sbjct: 892 GGASHPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIG 951
Query: 956 ITLAGHQKKILNSIHSMRVQ 975
+TLAGHQKKIL S+ M+ Q
Sbjct: 952 VTLAGHQKKILASVQHMKSQ 971
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 1070 bits (2766), Expect = 0.0
Identities = 538/1010 (53%), Positives = 694/1010 (68%), Gaps = 57/1010 (5%)
Query: 13 SAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWL 72
S V+ + L+DT T ELGW P +GW+ ++ DE+ I TYQVCNV EPNQNNWL
Sbjct: 122 SHVSNNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWL 181
Query: 73 LTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEA 132
T +I+R A +IY EM+FT+RDC+S+P V G+CKETFNL+Y E+D K +
Sbjct: 182 RTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIK----FKPN 237
Query: 133 PYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVF 192
Y K+DTIAADESF+Q+D G R++K+NTE+R GP+ R GFYLAFQD GAC++L+SVRVF
Sbjct: 238 QYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVF 297
Query: 193 FKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGR 252
+KKCP V+N A+FP+T+ +S+SLV RG+C+ +AEE D P KLYC DG+W+VP+GR
Sbjct: 298 YKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTP-KLYCGADGDWLVPLGR 356
Query: 253 CTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADF 312
C C GYE E +C AC G +KA CS CP +S + EA+ +C C GY+RA+
Sbjct: 357 CICSTGYE-EIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEK 415
Query: 313 DPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSR 372
DPP +ACT PS PRNV+ +NET++ILEW PP +TGGR D+TY++ICKKC D C
Sbjct: 416 DPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCED 475
Query: 373 CDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQA 432
C + F+PR GL V + +H YTF+I+A+NGVS S P ++ +TT+Q
Sbjct: 476 CGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQD 535
Query: 433 APSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR 492
APS + ++ + A+ SI LSW P NG ILDYEI+YYEKEH + S RS+ +
Sbjct: 536 APSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVI 595
Query: 493 IDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVF 552
I GL+P YV +R RT GY +S K F+T + + + Q+ +IA +A G
Sbjct: 596 ITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQGQILVIATAAVGGFTL 655
Query: 553 VVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGS---PGMKIYIDPFTYEDPNEAVRE 609
+V L ++ R + Y K + S++ + G PG+K YIDP TYEDP+ AV E
Sbjct: 656 LVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHE 715
Query: 610 FAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEA 669
FAKEID S ++IE VIGAGEFGEV GRLK PGKREI VAIKTLK G+ ++QRRDFL EA
Sbjct: 716 FAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREA 775
Query: 670 SIMGQFDHPNIIRLEGVVTK---------------------------------------- 689
SIMGQFDHPNIIRLEGVVTK
Sbjct: 776 SIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRI 835
Query: 690 --SRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAA 747
RPVMI+ E+MENG+LDSFLR++DG FTVIQLVGMLRGIA+GMKYL++M YVHRDLAA
Sbjct: 836 PAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAA 895
Query: 748 RNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDV 807
RNILVNSNLVCKVSDFGLSR L+DD + YT++ GGKIP+RWTAPEAIAYRKF+SASD
Sbjct: 896 RNILVNSNLVCKVSDFGLSRVLEDD-PEAAYTTT-GGKIPIRWTAPEAIAYRKFSSASDA 953
Query: 808 WSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNS 867
WSYGIVMWEVMS+GERPYW+MSNQDVI +IE+ YRLP PM CPA+LHQLML CWQK+RN
Sbjct: 954 WSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNH 1013
Query: 868 RPRFAEIVNTLDKMIRNPASLKT-VATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMV 926
RP+F +IV+ LDK+IRNP++L T V I +P P +P++ F TV DWL +IKM
Sbjct: 1014 RPKFTDIVSFLDKLIRNPSALHTLVEDILVMPESP---GEVPEYPLFVTVGDWLDSIKMG 1070
Query: 927 QYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQI 976
QY+++F+ AGFT+ L+++M+ +D+ RIG+ L GHQ++I++SI ++R+ +
Sbjct: 1071 QYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQTLRLHM 1120
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 1039 bits (2687), Expect = 0.0
Identities = 519/987 (52%), Positives = 688/987 (69%), Gaps = 35/987 (3%)
Query: 14 AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLL 73
+ A E L+DT T + GW PA GW+ ++ DE+ I TYQVCNV PNQNNWL
Sbjct: 26 SAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLR 85
Query: 74 TTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAP 133
T+++ R GA R+Y E++FT+RDC+S+P V G+CKETFNLYY E+D + A E+
Sbjct: 86 TSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLG----ASTQESQ 141
Query: 134 YLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFF 193
+LK+DTIAADESF+ D G R +K+NTEVRS GPL++ GFYLAFQD GAC+++LS+R+++
Sbjct: 142 FLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYY 201
Query: 194 KKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRC 253
KKCP++V+N A F E +TGA+S+SLV RG C+ ++EE D P K+YC+ +GEW+VPIG+C
Sbjct: 202 KKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKC 260
Query: 254 TCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFD 313
C GYE E AC AC G +K++ + C+ CP +S S A A+ C C YYRA D
Sbjct: 261 VCSAGYE-ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
Query: 314 PPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRC 373
PP ACT PS P N+IS VN TS+ LEW PP + GGR D+TYN +C++C C C
Sbjct: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEAC 379
Query: 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAA 433
FVP+Q L + + +++L AH Y+F I+A+NGVS SP P + VNITTNQAA
Sbjct: 380 GSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAA 439
Query: 434 PSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARI 493
PS V ++ Q A S++L W +PEQPNGIIL+YEI+YYEK+ + S ++ T A +
Sbjct: 440 PSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATV 499
Query: 494 DGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFV 553
GL+PG YV QVRART AG G+FS M +T K R I + +
Sbjct: 500 SGLKPGTRYVFQVRARTSAGCGRFSQAMEVET-----GKPRPRYDTRTIVWICLTLITGL 554
Query: 554 VSLVAISIVCSRKRAYSKEAVYSDKLQ-HYSTGRGSPGM--------------KIYIDPF 598
V L+ + I R YSK SD+ + HY G+ P + + Y +P
Sbjct: 555 VVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPH 614
Query: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658
TYE+P A R F +EI+ S + IE++IG+G+ GEV GRL++PG+R++ VAIK LKAGY+
Sbjct: 615 TYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYT 674
Query: 659 EKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTV 718
E+QRRDFLSEASIMGQFDHPNIIRLEGVVT+ R MI+TE+MENG+LD+FLR +DGQFT+
Sbjct: 675 ERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTI 734
Query: 719 IQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTY 778
+QLVGMLRG+ AGM+YL+++ YVHRDLAARN+LV+SNLVCKVSDFGLSR L+DD D Y
Sbjct: 735 MQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDD-PDAAY 793
Query: 779 TSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIE 838
T++ GGKIP+RWTAPEAIA+R F+SASDVWS+G+VMWEV+++GERPYW+M+N+DVI+++E
Sbjct: 794 TTT-GGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVE 852
Query: 839 QDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVP 898
+ YRLP PM CP ALHQLMLDCW KDR RPRF++IV+ LD +IR+P SL+ AT++ P
Sbjct: 853 EGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCP 912
Query: 899 SQPLLDRSIPDFTAFT------TVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLL 952
P RS D + TV DWL +I+M +YRD F G++SL +V +M ++D+
Sbjct: 913 -PPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVR 971
Query: 953 RIGITLAGHQKKILNSIHSMRVQISQS 979
+GITL GHQKKIL SI +MR Q++ +
Sbjct: 972 ALGITLMGHQKKILGSIQTMRAQLTST 998
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 932 bits (2409), Expect = 0.0
Identities = 480/1017 (47%), Positives = 653/1017 (64%), Gaps = 65/1017 (6%)
Query: 6 LLLLLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFE 65
L +LLL S+V A+EE L+DT T+E+GW P GW+EVS D+ RT++ C+V
Sbjct: 20 LWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAG 79
Query: 66 P----NQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVI 121
Q+NWL T F+ RRGA R + + F+VR CSSL G+C+ETF LYY + +
Sbjct: 80 APPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPD 139
Query: 122 ATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRL------------------MKVNTEVR 163
+ + W + KVDTIAADESF +++N + R
Sbjct: 140 SPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKER 199
Query: 164 SFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETM-TGAESTSLVIAR 222
SFGPLT+ GFY+AFQD GAC++L++VR+F CP+++++FA FPET +GA SLV A
Sbjct: 200 SFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAV 259
Query: 223 GTCIPNAEEVD---------VPIKLYCNGDGEWMVPIGRCTCKPGYEP-ENSVACKACPA 272
GTC+ +AE + P +L+CNG+G+WMV +G C C+PGY+P AC+ACP
Sbjct: 260 GTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPR 319
Query: 273 GTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISI 332
G +K+S CS CP+ S +P A+P+C C G+YRA DPPE CT PS P+ +
Sbjct: 320 GLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFE 379
Query: 333 VNETSIILEWHPPRETGGRDDVTYNIICKKCRADRR-------SCSRCDDNVEFVPRQLG 385
V ++++L W PRE GGR D+ +N++CK+C + +C RC D V F PRQ G
Sbjct: 380 VQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRG 439
Query: 386 LTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSA 445
LTE RV + L AH PY ++QA+NGVS SP PPQ ++N++T+ PS VP++HQVS
Sbjct: 440 LTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSR 499
Query: 446 TMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQ 505
SIT+SWPQP+Q NG ILDY++RYY++ +E +S S+TNTA + L PG +Y Q
Sbjct: 500 ASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQ 559
Query: 506 VRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVV--SLVAISIVC 563
VRART AG+G + GK+ FQTL + S+L E+L L+ GS + F++ ++ +++V
Sbjct: 560 VRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVF 619
Query: 564 SRKRAYSKEAVYSDKLQHYSTGRGSPGM--KIYIDPFTYEDPNEAVREFAKEIDVSFVKI 621
RKR + Y+++LQ YS SPG+ K YIDP TYEDP +A+RE A+E+D +++KI
Sbjct: 620 QRKR---RGTGYTEQLQQYS----SPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKI 672
Query: 622 EEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNII 681
EEVIG G FGEV +GRL+ G+RE VAI+ L AG +E + FL A+++GQF HPNI+
Sbjct: 673 EEVIGTGSFGEVRQGRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNIL 732
Query: 682 RLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYV 741
RLEGVVTKSRP+M++TEFME G LDSFLRQ +GQF+ +QLV M RG+AA M+YL+ +V
Sbjct: 733 RLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFV 792
Query: 742 HRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKF 801
HR L+A ++LVNS+LVCKV+ G S G +RW APE IA+ K
Sbjct: 793 HRSLSAHSVLVNSHLVCKVARLG--------------HSPQGPSCLLRWAAPEVIAHGKH 838
Query: 802 TSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCW 861
T++SDVWS+GI+MWEVMS+GERPYWDMS Q+V+NAIEQ++RLPPP CP LH LMLD W
Sbjct: 839 TTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTW 898
Query: 862 QKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLS 921
QKDR RP F ++V DKMIR P +L+ PSQ LL DF + WLS
Sbjct: 899 QKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLS 958
Query: 922 AIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRVQISQ 978
AI + Y+D+F G + V Q++ EDL +GITLAGHQKK+L+ I ++ + Q
Sbjct: 959 AIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQ 1015
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 885 bits (2288), Expect = 0.0
Identities = 474/981 (48%), Positives = 634/981 (64%), Gaps = 40/981 (4%)
Query: 9 LLLASAVAAMEETLMDTRTATAELGWTANP-ASGWEEVSGYDENLNTIRTYQVCNVFEPN 67
L A+A E L+D A ELGW +P GW+ + ++ I Y VCNV +
Sbjct: 18 LAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGD 76
Query: 68 QNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSA 127
Q+NWL T ++ R A RI+ E++FTVRDC+S P SCKETFNLYY E+D T
Sbjct: 77 QDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTN--- 133
Query: 128 FWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLL 187
+ + + K+DTIA DE DF R +K+N E RS GPLTR GFYLAFQD GAC++LL
Sbjct: 134 -FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALL 192
Query: 188 SVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCI------PNAEEVDVPIKLYCN 241
SVRV++KKCP ++Q A FPET+ G+++ SL GTC+ P EE +++C
Sbjct: 193 SVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP----RMHCA 248
Query: 242 GDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPIC 301
DGEW+VPIG+C C+ GYE AC+AC G FK C CP ++ E + C
Sbjct: 249 VDGEWLVPIGQCLCQAGYEKVED-ACQACSPGFFKFEASESPCLECPEHTLPSPEGATSC 307
Query: 302 TCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICK 361
C G++RA DP + CT PS P + ++ + L W PP+++GGR+D+ Y++ C+
Sbjct: 308 ECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCE 367
Query: 362 KCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVS---SKSPF 418
+C + C C+ +V + GLT V++S L H YTF ++A NGVS + F
Sbjct: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVTSRSF 427
Query: 419 PPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEK-EHN 477
VS+N Q P V + + S T S++ S P P+Q + YE+ Y +K + N
Sbjct: 428 RTASVSIN----QTEPPKVRLEGR-STTSLSVSWSIPPPQQSR--VWKYEVTYRKKGDSN 480
Query: 478 EFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELRE 537
+N + R++ + +D L P Y+VQV+A T G G S FQTL+ + +
Sbjct: 481 SYN--VRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLA-- 536
Query: 538 QLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDP 597
+ G A GVV ++ L + R+R ++ A S + ++S +K Y+DP
Sbjct: 537 ----VIGGVAVGVVLLLVLAGVGFFIHRRRK-NQRARQSPEDVYFSKSEQLKPLKTYVDP 591
Query: 598 FTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLP-GKREIYVAIKTLKAG 656
TYEDPN+AV +F EI S V ++VIGAGEFGEVYKG LK GK+E+ VAIKTLKAG
Sbjct: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651
Query: 657 YSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQF 716
Y+EKQR DFL EA IMGQF H NIIRLEGV++K +P+MIITE+MENGALD FLR+ DG+F
Sbjct: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711
Query: 717 TVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDP 776
+V+QLVGMLRGIAAGMKYLA MNYVHRDLAARNILVNSNLVCKVSDFGLSR L+DD +
Sbjct: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDP-EA 770
Query: 777 TYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINA 836
TYT+S GGKIP+RWTAPEAI+YRKFTSASDVWS+GIVMWEVM++GERPYW++SN +V+ A
Sbjct: 771 TYTTS-GGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKA 829
Query: 837 IEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITA 896
I +RLP PMDCP+A++QLM+ CWQ++R RP+FA+IV+ LDK+IR P SLKT+A
Sbjct: 830 INDGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDP 889
Query: 897 VPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGI 956
S L S + F TV +WL +IKM QY + F+ AG+T+++ V QMT++D+ RIG+
Sbjct: 890 RVSIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGV 949
Query: 957 TLAGHQKKILNSIHSMRVQIS 977
L GHQK+I S+ ++ Q++
Sbjct: 950 RLPGHQKRIAYSLLGLKDQVN 970
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 822 bits (2124), Expect = 0.0
Identities = 424/976 (43%), Positives = 618/976 (63%), Gaps = 22/976 (2%)
Query: 17 AMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTF 76
A E L+D++ + AELGWTA P++GWEE+SG DE+ IRTYQVCNV EPNQ+NWL T +
Sbjct: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
Query: 77 INRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLK 136
I+R RI+ E++FT+RDCSS+P G+CKETFN+YY ET++ + + P K
Sbjct: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPR-K 151
Query: 137 VDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKC 196
+DTIAADESF+Q D G R MK+NTEVR GPL+R GF+LAFQD GAC++L+SVRV++K+C
Sbjct: 152 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQC 211
Query: 197 PSIVQNFAVFPETMTGAESTSLVIARGTCIPNAE-EVDVPIKLYCNGDGEWMVPIGRCTC 255
+ V+ A FP T + ++LV GTC+ ++E E P +++C DGEW+VP+GRC+C
Sbjct: 212 RATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSC 271
Query: 256 KPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPP 315
G++ E C+ACP G +K S CS CP +SR+ AS C C+ Y R+ DPP
Sbjct: 272 SAGFQ-ERGDFCEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPP 330
Query: 316 EVACTSVPSGPRNVISIVNETSIILE--WHPPRETGGRDDVTYNIICKKCRAD--RRSCS 371
+CT PS PR++ ++ + ++L W PP ++GGR DVTY+++C +C + +C
Sbjct: 331 SASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACE 390
Query: 372 RCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFP-PQHVSVNITTN 430
C V F+PRQ GL E ++ L YT + A+NGVS + + V ++T
Sbjct: 391 PCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTG 450
Query: 431 QAAPSTVPIMHQVSATMRSITLSWPQP---EQPNGIILDYEIRYYEKEHNEFNSSMARSQ 487
AP + + +S++LSW +P P +YEIRYYEK +E SM ++
Sbjct: 451 PGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTEYEIRYYEKGQSEQTYSMVKTG 510
Query: 488 TNTARIDGLRPGMVYVVQVRARTVAGYGK---FSGKMCFQTLTDDDYKSELREQLPLIAG 544
T + L+P YV Q+RA + + F+ + QTL + S R+Q P I
Sbjct: 511 APTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTL--GEAASGSRDQSPAIVV 568
Query: 545 SAA--AGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYED 602
+ + ++ + S++++ + R +Y K + + P + ++DP + D
Sbjct: 569 TVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAHDEEELYFHFKVPTRRTFLDPQSCGD 628
Query: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQR 662
+AV FAKE+D V +E +G G FGE+ G L+LPG++E+ VA+ L+ S+ QR
Sbjct: 629 LLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQR 688
Query: 663 RDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLV 722
FL+EA +GQFDH +I+RLEGVVT+ +MI+TE+M +GALD FLR+++GQ QL+
Sbjct: 689 LGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFLRRHEGQLVAGQLM 748
Query: 723 GMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSL 782
G+L G+A+ MKYL+EM YVHR LAAR++LV+S+LVCK+S FG D S+ YT+ +
Sbjct: 749 GLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFGRG---PRDRSEAVYTT-M 804
Query: 783 GGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYR 842
G+ P W APE + + F+SASDVWS+GI+MWEVM+FGERPYWDMS QDVI A+E +R
Sbjct: 805 SGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFR 864
Query: 843 LPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPL 902
LPPP +CP LH+LMLDCWQKD RPRF++I + L KM+++P K T P PL
Sbjct: 865 LPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCALTTCPRPPTPL 924
Query: 903 LDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQ 962
DR+ F +F +V WL A+ + +Y+DSF AG+ SL+ V +MT++DL+ +GI+LA H+
Sbjct: 925 ADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDLVSLGISLAEHR 984
Query: 963 KKILNSIHSMRVQISQ 978
+ +L+ I +++ ++ Q
Sbjct: 985 EALLSGISALQARVLQ 1000
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 738 bits (1904), Expect = 0.0
Identities = 423/991 (42%), Positives = 585/991 (59%), Gaps = 42/991 (4%)
Query: 1 MALDYLLLLLLASAVAAMEETLMDTRTATAELGWTANPAS-GWEEVSGYDENLNTIRTYQ 59
+ L LL L A E TLMDT A ELGW +P GW E N + YQ
Sbjct: 9 LGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLYMYQ 67
Query: 60 VCNVF-EPNQNNWLLTTFINR-RGAHRIYTEMRFTVRDCSSLPNVPG--SCKETFNLYYY 115
C + + ++WL + +I R A R++ E++FTVRDC S P G CKETFNL Y
Sbjct: 68 DCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYM 127
Query: 116 ETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYL 175
E+D + + + KV T+AAD+SF+ D +K+N E S G LTR G YL
Sbjct: 128 ESDQDVGIQLR----RPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYL 183
Query: 176 AFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVP 235
AF + GAC++L+SVRVF+++CP + A FP+T+ G LV GTC+P+A P
Sbjct: 184 AFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRP 241
Query: 236 I---KLYCNGDGEWMVPIGRCTCKPGYEPENS-VACKACPAGTFKASQEAEGCSHCPSNS 291
+++C+ DGEW+VP+GRC C+PGYE S AC ACP+G+++ + C CP S
Sbjct: 242 SGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQS 301
Query: 292 RSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGR 351
+ +E + ICTC +G+YRA + P+VACT PS PRN+ + T + L W PP +TGGR
Sbjct: 302 TAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGR 361
Query: 352 DDVTYNIICKKCRA---DRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQA 408
DV Y++ C +C+ D C C V F P GLT V ++ L + YTF+++A
Sbjct: 362 QDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEA 421
Query: 409 INGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWP--QPEQPNGIILD 466
NGVS SV+I+ A + + V R + L+W +P P G L
Sbjct: 422 QNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLT 480
Query: 467 YEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTL 526
YE+ ++ + + T L+P Y+V+VR T G G FS
Sbjct: 481 YELHVLNQDEERYQMVLEPRVLLTE----LQPDTTYIVRVRMLTPLGPGPFS-------- 528
Query: 527 TDDDYKSELREQLPLIAGSAAAGVVFVVSLVA---ISIVCSRKRAYSKEAVYSDKLQHYS 583
D ++++ L G A V+F + L A + I+ R R ++ + +
Sbjct: 529 PDHEFRTSPPVSRGLTGGEIVA-VIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATD 587
Query: 584 TGRGSP-GMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPG 642
R +K Y+D YEDP + +F +E+D +++ ++ VIG GEFGEVY+G L+LP
Sbjct: 588 VDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPS 647
Query: 643 KREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMEN 702
+ VAIKTLK Q +FL EA+IMGQF HP+I+ LEGVVTK +P+MIITEFMEN
Sbjct: 648 QDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMEN 707
Query: 703 GALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSD 762
GALD+FLR+ + Q QLV ML+GIA+GM YL+ NYVHRDLAARNILVN NL CKVSD
Sbjct: 708 GALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSD 767
Query: 763 FGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGE 822
FGL+R L D D TY + GGKIP+RWTAPEAIA+R FT+ASDVWS+GIVMWEV+SFG+
Sbjct: 768 FGLTRLLDD--FDGTYETQ-GGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
Query: 823 RPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMI 882
+PY +MSNQ+V+ +IE YRLPPP+DCPA L++LM +CW DR RP F ++ L++++
Sbjct: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
Query: 883 RNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQL 942
NP SL+T+A + L S D + TV +WL +I+M +Y F +AG +++
Sbjct: 885 ANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMEC 944
Query: 943 VTQMTSEDLLRIGITLAGHQKKILNSIHSMR 973
V ++T+EDL ++GITL GHQK+IL SI +
Sbjct: 945 VLELTAEDLTQMGITLPGHQKRILCSIQGFK 975
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 556 bits (1434), Expect = e-158
Identities = 267/513 (52%), Positives = 357/513 (69%), Gaps = 7/513 (1%)
Query: 19 EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFIN 78
E L+D++T ELGW + P+ GWEE+SG DE+ IRTYQVCNV + +QNNWL T ++
Sbjct: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
Query: 79 RRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVD 138
R A +IY E++FT+RDC+S+P V G+CKETFNLYY E+D K + E + K+D
Sbjct: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
Query: 139 TIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPS 198
TIAADESF+Q+D G R++K+NTE+R GP+ + GFYLAFQD GAC++L+SVRV+FKKCP
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
Query: 199 IVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPG 258
V+N A+FP+T+ +S SLV RG+C+ N++E D P ++YC+ +GEW+VPIG+C+C G
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
Query: 259 YEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVA 318
YE E C+AC G +KA C+ CP +S + + S C C Y+RAD DPP +A
Sbjct: 263 YE-ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
Query: 319 CTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVE 378
CT PS PRNVIS +NETS+IL+W P +TGGR DVT+NIICKKC + + C C NV
Sbjct: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
Query: 379 FVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP 438
F+PRQ GLT V+++ L AHT YTF+I A+NGVS S P Q +V+ITTNQAAPS V
Sbjct: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
Query: 439 IMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRP 498
+ + + SI+LSW +PE PNGIILDYE++YYEK+ E + ++ R++ I L+P
Sbjct: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
Query: 499 GMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDY 531
+YV Q+RART AGYG S K F+T D Y
Sbjct: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 451 bits (1161), Expect = e-126
Identities = 213/419 (50%), Positives = 285/419 (68%), Gaps = 6/419 (1%)
Query: 14 AVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLL 73
+ A E L+DT T + GW PA GW+ ++ DE+ I TYQVCNV PNQNNWL
Sbjct: 26 SAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLR 85
Query: 74 TTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAP 133
T+++ R GA R+Y E++FT+RDC+S+P V G+CKETFNLYY E+D + A E+
Sbjct: 86 TSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLG----ASTQESQ 141
Query: 134 YLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFF 193
+LK+DTIAADESF+ D G R +K+NTEVRS GPL++ GFYLAFQD GAC+++LS+R+++
Sbjct: 142 FLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYY 201
Query: 194 KKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRC 253
KKCP++V+N A F E +TGA+S+SLV RG C+ ++EE D P K+YC+ +GEW+VPIG+C
Sbjct: 202 KKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTP-KMYCSAEGEWLVPIGKC 260
Query: 254 TCKPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFD 313
C GYE E AC AC G +K++ + C+ CP +S S A A+ C C YYRA D
Sbjct: 261 VCSAGYE-ERRDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALD 319
Query: 314 PPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRC 373
PP ACT PS P N+IS VN TS+ LEW PP + GGR D+TYN +C++C C C
Sbjct: 320 PPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEAC 379
Query: 374 DDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQA 432
FVP+Q L + + +++L AH Y+F I+A+NGVS SP P + VNITTNQA
Sbjct: 380 GSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 278 bits (710), Expect = 2e-74
Identities = 129/245 (52%), Positives = 178/245 (72%), Gaps = 2/245 (0%)
Query: 17 AMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTF 76
A E L+D++ + AELGWTA P++GWEE+SG DE+ IRTYQVCNV EPNQ+NWL T +
Sbjct: 33 AEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGW 92
Query: 77 INRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLK 136
I+R RI+ E++FT+RDCSS+P G+CKETFN+YY ET++ + + P K
Sbjct: 93 ISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRP-RK 151
Query: 137 VDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKC 196
+DTIAADESF+Q D G R MK+NTEVR GPL+R GF+LAFQD GAC++L+SVRV++K+C
Sbjct: 152 IDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQC 211
Query: 197 PSIVQNFAVFPETMTGAESTSLVIARGTCIPNAE-EVDVPIKLYCNGDGEWMVPIGRCTC 255
+ V+ A FP T + ++LV GTC+ ++E E P +++C DGEW+VP+GRC+C
Sbjct: 212 RATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSC 271
Query: 256 KPGYE 260
G++
Sbjct: 272 SAGFQ 276
>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
Length = 526
Score = 228 bits (581), Expect = 2e-59
Identities = 122/302 (40%), Positives = 184/302 (60%), Gaps = 13/302 (4%)
Query: 579 LQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRL 638
+ HY G K+ + P P + + A EI +K+E+ +GAG+FGEV+
Sbjct: 223 VDHYKKGNDGLCQKLSV-PCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATY 281
Query: 639 KLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITE 698
K VA+KT+K G + FL+EA++M H +++L VVTK P+ IITE
Sbjct: 282 NKHTK----VAVKTMKPGSMSVEA--FLAEANVMKTLQHDKLVKLHAVVTKE-PIYIITE 334
Query: 699 FMENGALDSFLRQNDGQFTVI-QLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLV 757
FM G+L FL+ ++G + +L+ IA GM ++ + NY+HRDL A NILV+++LV
Sbjct: 335 FMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLV 394
Query: 758 CKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817
CK++DFGL+R ++D+ YT+ G K P++WTAPEAI + FT SDVWS+GI++ E+
Sbjct: 395 CKIADFGLARVIEDNE----YTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEI 450
Query: 818 MSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNT 877
+++G PY MSN +VI A+E+ YR+P P +CP L+ +M+ CW+ RP F I +
Sbjct: 451 VTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSV 510
Query: 878 LD 879
LD
Sbjct: 511 LD 512
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 227 bits (579), Expect = 4e-59
Identities = 164/507 (32%), Positives = 255/507 (50%), Gaps = 46/507 (9%)
Query: 393 ISSLWAHTPYTFDIQAINGVSSKSPFP-PQHVSVNITTNQAAPSTV-PIMHQVSATMRSI 450
IS L T Y ++QA N + + +VS A V P+ H++ +
Sbjct: 797 ISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFEN-NVV 855
Query: 451 TLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQ---TNTARIDGLRPGMVYVVQVR 507
L W +P++PNG+I+ YE+ Y E + ++R R+ GL PG Y V++R
Sbjct: 856 HLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGN-YSVRIR 914
Query: 508 ARTVAGYGKFSGKMCFQTLTDDDYKSELREQL--PLIAGSAAAGVVFVVSLVAISI-VCS 564
A ++AG G ++ F D S + + + PLI VF+ S+V SI +
Sbjct: 915 ATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLI-------FVFLFSVVIGSIYLFL 967
Query: 565 RKRAYSKEA--VYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIE 622
RKR +Y+ Y + +Y+ P+E E+ + +
Sbjct: 968 RKRQPDGPLGPLYASSNPEYLSASDVFPCSVYV-------PDEW------EVSREKITLL 1014
Query: 623 EVIGAGEFGEVYKGRLK--LPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNI 680
+G G FG VY+G + + G+ E VA+KT+ S ++R +FL+EAS+M F ++
Sbjct: 1015 RELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV 1074
Query: 681 IRLEGVVTKSRPVMIITEFMENGALDSFLRQ-------NDGQF--TVIQLVGMLRGIAAG 731
+RL GVV+K +P +++ E M +G L S+LR N G+ T+ +++ M IA G
Sbjct: 1075 VRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADG 1134
Query: 732 MKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 791
M YL +VHRDLAARN +V + K+ DFG++R D Y G +PVRW
Sbjct: 1135 MAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWM 1191
Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 851
APE++ FT++SD+WS+G+V+WE+ S E+PY +SN+ V+ + L P +CP
Sbjct: 1192 APESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPE 1251
Query: 852 ALHQLMLDCWQKDRNSRPRFAEIVNTL 878
+ LM CWQ + RP F EIVN L
Sbjct: 1252 RVTDLMRMCWQFNPKMRPTFLEIVNLL 1278
>gi|119395736 insulin receptor isoform Long precursor [Homo sapiens]
Length = 1382
Score = 227 bits (579), Expect = 4e-59
Identities = 164/507 (32%), Positives = 255/507 (50%), Gaps = 46/507 (9%)
Query: 393 ISSLWAHTPYTFDIQAINGVSSKSPFP-PQHVSVNITTNQAAPSTV-PIMHQVSATMRSI 450
IS L T Y ++QA N + + +VS A V P+ H++ +
Sbjct: 809 ISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFEN-NVV 867
Query: 451 TLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQ---TNTARIDGLRPGMVYVVQVR 507
L W +P++PNG+I+ YE+ Y E + ++R R+ GL PG Y V++R
Sbjct: 868 HLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGN-YSVRIR 926
Query: 508 ARTVAGYGKFSGKMCFQTLTDDDYKSELREQL--PLIAGSAAAGVVFVVSLVAISI-VCS 564
A ++AG G ++ F D S + + + PLI VF+ S+V SI +
Sbjct: 927 ATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLI-------FVFLFSVVIGSIYLFL 979
Query: 565 RKRAYSKEA--VYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIE 622
RKR +Y+ Y + +Y+ P+E E+ + +
Sbjct: 980 RKRQPDGPLGPLYASSNPEYLSASDVFPCSVYV-------PDEW------EVSREKITLL 1026
Query: 623 EVIGAGEFGEVYKGRLK--LPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNI 680
+G G FG VY+G + + G+ E VA+KT+ S ++R +FL+EAS+M F ++
Sbjct: 1027 RELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHV 1086
Query: 681 IRLEGVVTKSRPVMIITEFMENGALDSFLRQ-------NDGQF--TVIQLVGMLRGIAAG 731
+RL GVV+K +P +++ E M +G L S+LR N G+ T+ +++ M IA G
Sbjct: 1087 VRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADG 1146
Query: 732 MKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 791
M YL +VHRDLAARN +V + K+ DFG++R D Y G +PVRW
Sbjct: 1147 MAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWM 1203
Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 851
APE++ FT++SD+WS+G+V+WE+ S E+PY +SN+ V+ + L P +CP
Sbjct: 1204 APESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPE 1263
Query: 852 ALHQLMLDCWQKDRNSRPRFAEIVNTL 878
+ LM CWQ + RP F EIVN L
Sbjct: 1264 RVTDLMRMCWQFNPKMRPTFLEIVNLL 1290
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 227 bits (578), Expect = 5e-59
Identities = 160/506 (31%), Positives = 254/506 (50%), Gaps = 43/506 (8%)
Query: 390 RVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP-IMHQVSATMR 448
R IS+L T Y DI + N + K + T +P +
Sbjct: 787 RTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPEN 846
Query: 449 SITLSWPQPEQPNGIILDYEIRYYEK--EHNEFNSSMARSQTNTARIDGLRPGMVYVVQV 506
SI L WP+PE PNG+IL YEI+Y + + E S + A+++ L PG Y ++
Sbjct: 847 SIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN-YTARI 905
Query: 507 RARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRK 566
+A +++G G ++ + F Y++ + LI A ++ V LV + V RK
Sbjct: 906 QATSLSGNGSWTDPVFFYVQAKTGYENFIH----LIIALPVAVLLIVGGLVIMLYVFHRK 961
Query: 567 RAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYED---PNEAVREFAKEIDVSFVKIEE 623
R S+ G G + + F+ D P+E E A+E + +
Sbjct: 962 RNNSR------------LGNGVLYASVNPEYFSAADVYVPDEW--EVAREK----ITMSR 1003
Query: 624 VIGAGEFGEVYKGRLK--LPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNII 681
+G G FG VY+G K + + E VAIKT+ S ++R +FL+EAS+M +F+ +++
Sbjct: 1004 ELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVV 1063
Query: 682 RLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQF---------TVIQLVGMLRGIAAGM 732
RL GVV++ +P ++I E M G L S+LR + ++ +++ M IA GM
Sbjct: 1064 RLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGM 1123
Query: 733 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
YL +VHRDLAARN +V + K+ DFG++R D Y G +PVRW +
Sbjct: 1124 AYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTR---DIYETDYYRKGGKGLLPVRWMS 1180
Query: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAA 852
PE++ FT+ SDVWS+G+V+WE+ + E+PY +SN+ V+ + + L P +CP
Sbjct: 1181 PESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDM 1240
Query: 853 LHQLMLDCWQKDRNSRPRFAEIVNTL 878
L +LM CWQ + RP F EI++++
Sbjct: 1241 LFELMRMCWQYNPKMRPSFLEIISSI 1266
>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
Length = 1074
Score = 225 bits (574), Expect = 1e-58
Identities = 116/270 (42%), Positives = 164/270 (60%), Gaps = 5/270 (1%)
Query: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
EI +++ IG G+FG+V++G P + VAIKT K S+ R FL EA M
Sbjct: 438 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 497
Query: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
QFDHP+I++L GV+T++ PV II E G L SFL+ + L+ ++ +
Sbjct: 498 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 556
Query: 733 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
YL +VHRD+AARN+LV+SN K+ DFGLSRY++D T Y + GK+P++W A
Sbjct: 557 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST----YYKASKGKLPIKWMA 612
Query: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAA 852
PE+I +R+FTSASDVW +G+ MWE++ G +P+ + N DVI IE RLP P +CP
Sbjct: 613 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 672
Query: 853 LHQLMLDCWQKDRNSRPRFAEIVNTLDKMI 882
L+ LM CW D + RPRF E+ L ++
Sbjct: 673 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 702
>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
Length = 1052
Score = 225 bits (574), Expect = 1e-58
Identities = 116/270 (42%), Positives = 164/270 (60%), Gaps = 5/270 (1%)
Query: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
EI +++ IG G+FG+V++G P + VAIKT K S+ R FL EA M
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTM 475
Query: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
QFDHP+I++L GV+T++ PV II E G L SFL+ + L+ ++ +
Sbjct: 476 RQFDHPHIVKLIGVITEN-PVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTAL 534
Query: 733 KYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTA 792
YL +VHRD+AARN+LV+SN K+ DFGLSRY++D T Y + GK+P++W A
Sbjct: 535 AYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST----YYKASKGKLPIKWMA 590
Query: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAA 852
PE+I +R+FTSASDVW +G+ MWE++ G +P+ + N DVI IE RLP P +CP
Sbjct: 591 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 650
Query: 853 LHQLMLDCWQKDRNSRPRFAEIVNTLDKMI 882
L+ LM CW D + RPRF E+ L ++
Sbjct: 651 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
Length = 543
Score = 224 bits (572), Expect = 2e-58
Identities = 123/282 (43%), Positives = 175/282 (62%), Gaps = 12/282 (4%)
Query: 599 TYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYS 658
T + + + + A EI +++E +G G FGEV+ G K VAIKTLK G
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312
Query: 659 EKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTV 718
+ FL EA IM + H ++ L VV++ P+ I+TEFM G+L FL++ DG++
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSEE-PIYIVTEFMSKGSLLDFLKEGDGKYLK 369
Query: 719 I-QLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPT 777
+ QLV M IA GM Y+ MNY+HRDL A NILV NLVCK++DFGL+R ++D+
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---- 425
Query: 778 YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAI 837
YT+ G K P++WTAPEA Y +FT SDVWS+GI+ E+++ G PY M N++V+ +
Sbjct: 426 YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQV 485
Query: 838 EQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLD 879
E+ YR+P P CP +LH+LM CW+KD + RP F I + L+
Sbjct: 486 ERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 223 bits (569), Expect = 5e-58
Identities = 113/272 (41%), Positives = 173/272 (63%), Gaps = 10/272 (3%)
Query: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
E++ + + ++ +G G++GEVY+G K K + VA+KTLK E + +FL EA++M
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVE--EFLKEAAVM 290
Query: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQ-NDGQFTVIQLVGMLRGIAAG 731
+ HPN+++L GV T+ P IITEFM G L +LR+ N + + L+ M I++
Sbjct: 291 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 350
Query: 732 MKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 791
M+YL + N++HRDLAARN LV N + KV+DFGLSR + DT YT+ G K P++WT
Sbjct: 351 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDT----YTAHAGAKFPIKWT 406
Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 851
APE++AY KF+ SDVW++G+++WE+ ++G PY + V +E+DYR+ P CP
Sbjct: 407 APESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE 466
Query: 852 ALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIR 883
+++LM CWQ + + RP FAEI + M +
Sbjct: 467 KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 498
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 223 bits (569), Expect = 5e-58
Identities = 113/272 (41%), Positives = 173/272 (63%), Gaps = 10/272 (3%)
Query: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
E++ + + ++ +G G++GEVY+G K K + VA+KTLK E + +FL EA++M
Sbjct: 255 EMERTDITMKHKLGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVE--EFLKEAAVM 309
Query: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQ-NDGQFTVIQLVGMLRGIAAG 731
+ HPN+++L GV T+ P IITEFM G L +LR+ N + + L+ M I++
Sbjct: 310 KEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSA 369
Query: 732 MKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 791
M+YL + N++HRDLAARN LV N + KV+DFGLSR + DT YT+ G K P++WT
Sbjct: 370 MEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDT----YTAHAGAKFPIKWT 425
Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 851
APE++AY KF+ SDVW++G+++WE+ ++G PY + V +E+DYR+ P CP
Sbjct: 426 APESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE 485
Query: 852 ALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIR 883
+++LM CWQ + + RP FAEI + M +
Sbjct: 486 KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 517
>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
Length = 537
Score = 222 bits (566), Expect = 1e-57
Identities = 114/268 (42%), Positives = 172/268 (64%), Gaps = 12/268 (4%)
Query: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
EI +++ + +G G+FGEV+ G K VAIKTLK G + FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318
Query: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVI-QLVGMLRGIAAG 731
+ H +++L VV++ P+ I+TE+M G+L FL+ +G+ + LV M +AAG
Sbjct: 319 KKLKHDKLVQLYAVVSEE-PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377
Query: 732 MKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWT 791
M Y+ MNY+HRDL + NILV + L+CK++DFGL+R ++D+ YT+ G K P++WT
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE----YTARQGAKFPIKWT 433
Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPA 851
APEA Y +FT SDVWS+GI++ E+++ G PY M+N++V+ +E+ YR+P P DCP
Sbjct: 434 APEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPI 493
Query: 852 ALHQLMLDCWQKDRNSRPRFAEIVNTLD 879
+LH+LM+ CW+KD RP F + + L+
Sbjct: 494 SLHELMIHCWKKDPEERPTFEYLQSFLE 521
>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
Length = 534
Score = 221 bits (562), Expect = 3e-57
Identities = 118/302 (39%), Positives = 181/302 (59%), Gaps = 12/302 (3%)
Query: 579 LQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRL 638
+QHYS + + + + + A E+ + +E+ +G G F EV+ G
Sbjct: 228 VQHYSEKADGLCFNLTVIASSCTPQTSGLAKDAWEVARRSLCLEKKLGQGCFAEVWLGTW 287
Query: 639 KLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITE 698
K VAIKTLK G + FL EA IM + H +++L VV++ P+ I+TE
Sbjct: 288 NGNTK----VAIKTLKPGTMSPE--SFLEEAQIMKKLKHDKLVQLYAVVSEE-PIYIVTE 340
Query: 699 FMENGALDSFLRQNDGQFTVI-QLVGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLV 757
+M G+L FL+ +G+ + LV M +AAGM Y+ MNY+HRDL + NILV + L+
Sbjct: 341 YMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLI 400
Query: 758 CKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817
CK++DFGL+R ++D+ YT+ G K P++WTAPEA Y +FT SDVWS+GI++ E+
Sbjct: 401 CKIADFGLARLIEDNE----YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTEL 456
Query: 818 MSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNT 877
++ G PY M+N++V+ +E+ YR+P P DCP +LH+LM+ CW+KD RP F + +
Sbjct: 457 VTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSF 516
Query: 878 LD 879
L+
Sbjct: 517 LE 518
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,657,668
Number of Sequences: 37866
Number of extensions: 1719551
Number of successful extensions: 7688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 604
Number of HSP's successfully gapped in prelim test: 362
Number of HSP's that attempted gapping in prelim test: 4239
Number of HSP's gapped (non-prelim): 2053
length of query: 984
length of database: 18,247,518
effective HSP length: 112
effective length of query: 872
effective length of database: 14,006,526
effective search space: 12213690672
effective search space used: 12213690672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.