Guide to the Human Genome
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Name: INSR Sequence: fasta or formatted (1382aa) NCBI GI: 119395736
Description:

insulin receptor isoform Long precursor

Referenced in:

Organs and Hormones
Muscle
Pancreas and Insulin
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [1370aa] insulin receptor isoform Short precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.8         66           4
 C cysteine            3.4         47           2
 D aspartate           5.1         70           2
 E glutamate           7.7        106           2
 F phenylalanine       4.3         59           2
 G glycine             6.7         92           2
 H histidine           2.7         37           2
 I isoleucine          4.8         66           3
 K lysine              4.8         67           2
 L leucine             9.8        136           3
 M methionine          2.2         30           1
 N asparagine          5.2         72           2
 P proline             5.9         82           3
 Q glutamine           2.7         38           1
 R arginine            5.9         82           2
 S serine              7.6        105           3
 T threonine           5.0         69           2
 V valine              6.3         87           2
 W tryptophan          1.4         20           1
 Y tyrosine            3.7         51           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin receptor isoform Long precursor 
INSR                  0.989   insulin receptor isoform Short precursor 
IGF1R                 0.545   insulin-like growth factor 1 receptor precursor [Homo...
INSRR                 0.468   insulin receptor-related receptor precursor 
ROS1                  0.085   proto-oncogene c-ros-1 protein precursor 
ALK                   0.082   anaplastic lymphoma kinase 
LTK                   0.081   leukocyte receptor tyrosine kinase isoform 1 precurs...
LTK                   0.081   leukocyte receptor tyrosine kinase isoform 2 precurs...
MUSK                  0.079   skeletal muscle receptor tyrosine kinase 
NTRK2                 0.077   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK2                 0.077   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK3                 0.075   neurotrophic tyrosine kinase, receptor, type 3 isofo...
NTRK1                 0.075   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK1                 0.075   neurotrophic tyrosine kinase, receptor, type 1 isofor...
NTRK1                 0.075   neurotrophic tyrosine kinase, receptor, type 1 isofo...
EPHA5                 0.074   ephrin receptor EphA5 isoform b precursor 
AXL                   0.072   AXL receptor tyrosine kinase isoform 2 
NTRK3                 0.071   neurotrophic tyrosine kinase, receptor, type 3 isofo...
MERTK                 0.071   MER receptor tyrosine kinase precursor 
EPHB1                 0.071   ephrin receptor EphB1 precursor 
AXL                   0.070   AXL receptor tyrosine kinase isoform 1 
FGFR3                 0.070   fibroblast growth factor receptor 3 isoform 3 precu...
FGFR3                 0.070   fibroblast growth factor receptor 3 isoform 2 precur...
FGFR3                 0.070   fibroblast growth factor receptor 3 isoform 1 precurs...
LTK                   0.070   leukocyte receptor tyrosine kinase isoform 3 precur...
EPHA2                 0.069   ephrin receptor EphA2 
FGFR4                 0.069   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.069   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.069   fibroblast growth factor receptor 4 isoform 1 precur...
RET                   0.069   ret proto-oncogene isoform c 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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