Guide to the Human Genome
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Name: HCK Sequence: fasta or formatted (526aa) NCBI GI: 30795229
Description:

hemopoietic cell kinase isoform p61HCK

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         33           2
 C cysteine            1.7          9           1
 D aspartate           5.1         27           2
 E glutamate           8.4         44           2
 F phenylalanine       4.0         21           2
 G glycine             6.7         35           2
 H histidine           1.9         10           2
 I isoleucine          5.7         30           2
 K lysine              7.2         38           2
 L leucine             6.8         36           2
 M methionine          3.4         18           2
 N asparagine          3.4         18           1
 P proline             6.3         33           1
 Q glutamine           3.4         18           3
 R arginine            5.5         29           1
 S serine              8.0         42           2
 T threonine           5.1         27           2
 V valine              5.3         28           2
 W tryptophan          1.7          9           2
 Y tyrosine            4.0         21           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hemopoietic cell kinase isoform p61HCK 
LYN                   0.679   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
LYN                   0.669   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LCK                   0.626   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.626   lymphocyte-specific protein tyrosine kinase precurs...
BLK                   0.595   B lymphoid tyrosine kinase 
YES1                  0.562   viral oncogene yes-1 homolog 1 
FYN                   0.560   protein-tyrosine kinase fyn isoform a 
FYN                   0.553   protein-tyrosine kinase fyn isoform b 
SRC                   0.533   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.533   proto-oncogene tyrosine-protein kinase SRC 
FGR                   0.528   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.528   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.528   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.486   protein-tyrosine kinase fyn isoform c 
FRK                   0.425   fyn-related kinase 
SRMS                  0.324   src-related kinase lacking C-terminal regulatory tyr...
ABL1                  0.320   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL1                  0.316   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL2                  0.315   arg tyrosine kinase isoform e 
ABL2                  0.313   arg tyrosine kinase isoform c 
ABL2                  0.313   arg tyrosine kinase isoform b 
ABL2                  0.313   arg tyrosine kinase isoform d 
ABL2                  0.313   arg tyrosine kinase isoform a 
PTK6                  0.307   PTK6 protein tyrosine kinase 6 
TXK                   0.287   TXK tyrosine kinase 
TEC                   0.285   tec protein tyrosine kinase 
BTK                   0.283   Bruton agammaglobulinemia tyrosine kinase 
ITK                   0.269   IL2-inducible T-cell kinase 
CSK                   0.247   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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