Guide to the Human Genome
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Name: ABL1 Sequence: fasta or formatted (1130aa) NCBI GI: 62362414
Description:

c-abl oncogene 1, receptor tyrosine kinase isoform a

Referenced in:

Common Drug Targets
Retroviral Oncogene Homologs
Additional Interaction Domain Families
Non-Receptor Tyrosine Kinase Pathways
Zinc Finger Proteins

Other entries for this name:
alt prot [1149aa] c-abl oncogene 1, receptor tyrosine kinase isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         97           3
 C cysteine            1.2         14           1
 D aspartate           3.7         42           1
 E glutamate           8.0         90           3
 F phenylalanine       2.6         29           1
 G glycine             7.8         88           3
 H histidine           2.1         24           3
 I isoleucine          2.9         33           2
 K lysine              7.3         82           5
 L leucine             8.5         96           2
 M methionine          1.6         18           1
 N asparagine          3.5         40           2
 P proline             8.0         90           5
 Q glutamine           2.9         33           2
 R arginine            5.7         64           2
 S serine             10.6        120           5
 T threonine           5.8         65           2
 V valine              5.5         62           2
 W tryptophan          1.2         13           1
 Y tyrosine            2.7         30           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   c-abl oncogene 1, receptor tyrosine kinase isoform a... 
ABL1                  0.977   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.470   arg tyrosine kinase isoform a 
ABL2                  0.470   arg tyrosine kinase isoform c 
ABL2                  0.470   arg tyrosine kinase isoform b 
ABL2                  0.424   arg tyrosine kinase isoform d 
ABL2                  0.382   arg tyrosine kinase isoform e 
FRK                   0.158   fyn-related kinase 
YES1                  0.153   viral oncogene yes-1 homolog 1 
FYN                   0.151   protein-tyrosine kinase fyn isoform a 
FGR                   0.151   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.151   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.151   proto-oncogene tyrosine-protein kinase FGR 
SRC                   0.150   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.150   proto-oncogene tyrosine-protein kinase SRC 
FYN                   0.150   protein-tyrosine kinase fyn isoform b 
LCK                   0.149   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.149   lymphocyte-specific protein tyrosine kinase precurs...
HCK                   0.148   hemopoietic cell kinase isoform p61HCK 
LYN                   0.145   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.144   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
BTK                   0.140   Bruton agammaglobulinemia tyrosine kinase 
BLK                   0.140   B lymphoid tyrosine kinase 
TEC                   0.139   tec protein tyrosine kinase 
TXK                   0.137   TXK tyrosine kinase 
SRMS                  0.128   src-related kinase lacking C-terminal regulatory tyr...
CSK                   0.128   c-src tyrosine kinase 
CSK                   0.128   c-src tyrosine kinase 
ITK                   0.126   IL2-inducible T-cell kinase 
FYN                   0.124   protein-tyrosine kinase fyn isoform c 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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