Guide to the Human Genome
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Name: ABL1 Sequence: fasta or formatted (1149aa) NCBI GI: 62362412
Description:

c-abl oncogene 1, receptor tyrosine kinase isoform b

Referenced in:

Retroviral Oncogene Homologs
Additional Interaction Domain Families
Non-Receptor Tyrosine Kinase Pathways
Zinc Finger Proteins

Other entries for this name:
alt prot [1130aa] c-abl oncogene 1, receptor tyrosine kinase isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         99           3
 C cysteine            1.0         12           1
 D aspartate           3.7         43           1
 E glutamate           7.8         90           3
 F phenylalanine       2.7         31           1
 G glycine             8.1         93           3
 H histidine           2.4         28           3
 I isoleucine          2.9         33           2
 K lysine              7.1         82           5
 L leucine             8.2         94           2
 M methionine          1.6         18           1
 N asparagine          3.6         41           2
 P proline             8.2         94           5
 Q glutamine           3.1         36           2
 R arginine            5.8         67           2
 S serine             10.2        117           3
 T threonine           5.7         65           2
 V valine              5.6         64           2
 W tryptophan          1.1         13           1
 Y tyrosine            2.5         29           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   c-abl oncogene 1, receptor tyrosine kinase isoform b... 
ABL1                  0.959   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL2                  0.461   arg tyrosine kinase isoform b 
ABL2                  0.460   arg tyrosine kinase isoform c 
ABL2                  0.460   arg tyrosine kinase isoform a 
ABL2                  0.416   arg tyrosine kinase isoform d 
ABL2                  0.381   arg tyrosine kinase isoform e 
FRK                   0.155   fyn-related kinase 
YES1                  0.150   viral oncogene yes-1 homolog 1 
FYN                   0.148   protein-tyrosine kinase fyn isoform a 
SRC                   0.148   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.148   proto-oncogene tyrosine-protein kinase SRC 
FGR                   0.148   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.148   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.148   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.147   protein-tyrosine kinase fyn isoform b 
HCK                   0.147   hemopoietic cell kinase isoform p61HCK 
LCK                   0.146   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.146   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.141   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.141   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
BTK                   0.137   Bruton agammaglobulinemia tyrosine kinase 
BLK                   0.137   B lymphoid tyrosine kinase 
TEC                   0.136   tec protein tyrosine kinase 
TXK                   0.134   TXK tyrosine kinase 
SRMS                  0.125   src-related kinase lacking C-terminal regulatory tyr...
CSK                   0.125   c-src tyrosine kinase 
CSK                   0.125   c-src tyrosine kinase 
ITK                   0.124   IL2-inducible T-cell kinase 
FYN                   0.121   protein-tyrosine kinase fyn isoform c 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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