Guide to the Human Genome
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Name: IGF1R Sequence: fasta or formatted (1367aa) NCBI GI: 4557665
Description:

insulin-like growth factor 1 receptor precursor

Referenced in:

Growth Hormone and Related Hormones
Pancreas and Insulin
Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         72           2
 C cysteine            3.2         44           2
 D aspartate           4.5         62           2
 E glutamate           8.3        113           3
 F phenylalanine       3.4         47           2
 G glycine             6.7         91           3
 H histidine           1.7         23           2
 I isoleucine          5.3         73           3
 K lysine              5.0         69           2
 L leucine             8.5        116           3
 M methionine          2.9         39           1
 N asparagine          6.2         85           2
 P proline             5.9         81           2
 Q glutamine           2.6         35           2
 R arginine            5.9         80           2
 S serine              7.1         97           4
 T threonine           5.0         69           3
 V valine              6.4         87           2
 W tryptophan          1.5         21           1
 Y tyrosine            4.6         63           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin-like growth factor 1 receptor precursor [Homo... 
INSR                  0.555   insulin receptor isoform Short precursor 
INSR                  0.552   insulin receptor isoform Long precursor 
INSRR                 0.504   insulin receptor-related receptor precursor 
ALK                   0.091   anaplastic lymphoma kinase 
ROS1                  0.087   proto-oncogene c-ros-1 protein precursor 
LTK                   0.086   leukocyte receptor tyrosine kinase isoform 1 precurs...
LTK                   0.086   leukocyte receptor tyrosine kinase isoform 2 precurs...
MUSK                  0.079   skeletal muscle receptor tyrosine kinase 
NTRK2                 0.078   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK2                 0.078   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK1                 0.078   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK1                 0.078   neurotrophic tyrosine kinase, receptor, type 1 isofor...
NTRK1                 0.078   neurotrophic tyrosine kinase, receptor, type 1 isofo...
AXL                   0.078   AXL receptor tyrosine kinase isoform 1 
AXL                   0.077   AXL receptor tyrosine kinase isoform 2 
NTRK3                 0.076   neurotrophic tyrosine kinase, receptor, type 3 isofo...
FGFR1                 0.075   fibroblast growth factor receptor 1 isoform 4 precur...
FGFR1                 0.075   fibroblast growth factor receptor 1 isoform 3 precur...
FGFR1                 0.075   fibroblast growth factor receptor 1 isoform 2 precur...
FGFR1                 0.075   fibroblast growth factor receptor 1 isoform 1 precu...
EPHA3                 0.073   ephrin receptor EphA3 isoform a precursor 
FGFR4                 0.073   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.073   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.073   fibroblast growth factor receptor 4 isoform 1 precur...
LTK                   0.073   leukocyte receptor tyrosine kinase isoform 3 precur...
FGFR2                 0.072   fibroblast growth factor receptor 2 isoform 9 precu...
FGFR2                 0.072   fibroblast growth factor receptor 2 isoform 3 precu...
FGFR3                 0.072   fibroblast growth factor receptor 3 isoform 3 precu...
FGFR3                 0.072   fibroblast growth factor receptor 3 isoform 2 precur...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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