Guide to the Human Genome
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Name: FYN Sequence: fasta or formatted (537aa) NCBI GI: 4503823
Description:

protein-tyrosine kinase fyn isoform a

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [534aa] protein-tyrosine kinase fyn isoform b
alt prot [482aa] protein-tyrosine kinase fyn isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         31           2
 C cysteine            1.7          9           2
 D aspartate           5.0         27           2
 E glutamate           7.6         41           2
 F phenylalanine       3.7         20           1
 G glycine             8.9         48           2
 H histidine           2.2         12           1
 I isoleucine          4.7         25           1
 K lysine              6.1         33           2
 L leucine             9.3         50           2
 M methionine          2.4         13           1
 N asparagine          3.9         21           2
 P proline             4.7         25           1
 Q glutamine           4.1         22           2
 R arginine            5.6         30           1
 S serine              5.6         30           3
 T threonine           6.7         36           2
 V valine              5.2         28           2
 W tryptophan          1.9         10           2
 Y tyrosine            4.8         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein-tyrosine kinase fyn isoform a 
FYN                   0.934   protein-tyrosine kinase fyn isoform b 
FYN                   0.853   protein-tyrosine kinase fyn isoform c 
YES1                  0.708   viral oncogene yes-1 homolog 1 
FGR                   0.676   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.676   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.676   proto-oncogene tyrosine-protein kinase FGR 
SRC                   0.664   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.664   proto-oncogene tyrosine-protein kinase SRC 
HCK                   0.544   hemopoietic cell kinase isoform p61HCK 
LCK                   0.517   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.517   lymphocyte-specific protein tyrosine kinase precurs...
LYN                   0.513   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.513   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
BLK                   0.502   B lymphoid tyrosine kinase 
FRK                   0.428   fyn-related kinase 
PTK6                  0.327   PTK6 protein tyrosine kinase 6 
ABL2                  0.317   arg tyrosine kinase isoform c 
ABL2                  0.317   arg tyrosine kinase isoform b 
ABL2                  0.317   arg tyrosine kinase isoform d 
ABL2                  0.317   arg tyrosine kinase isoform a 
ABL2                  0.316   arg tyrosine kinase isoform e 
ABL1                  0.313   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.313   c-abl oncogene 1, receptor tyrosine kinase isoform b...
SRMS                  0.304   src-related kinase lacking C-terminal regulatory tyr...
TXK                   0.283   TXK tyrosine kinase 
BTK                   0.273   Bruton agammaglobulinemia tyrosine kinase 
TEC                   0.273   tec protein tyrosine kinase 
ITK                   0.269   IL2-inducible T-cell kinase 
CSK                   0.241   c-src tyrosine kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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