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Search of human proteins with 47078300
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47078300 apoptosis related protein 3 isoform b [Homo
sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47078300 apoptosis related protein 3 isoform b [Homo sapiens] 595 e-170
gi|18105012 apoptosis related protein 3 isoform a [Homo sapiens] 366 e-101
gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens] 41 0.001
gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens] 41 0.001
gi|74136023 delta-like 1 homolog [Homo sapiens] 39 0.007
gi|4557679 jagged 1 precursor [Homo sapiens] 37 0.020
gi|134244285 Notch homolog 3 [Homo sapiens] 36 0.044
gi|208431817 protein kinase-like protein SgK493 [Homo sapiens] 36 0.044
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 35 0.098
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 35 0.098
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 35 0.098
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 35 0.098
gi|55770876 notch4 preproprotein [Homo sapiens] 35 0.098
gi|28269693 xylosyltransferase I [Homo sapiens] 34 0.13
gi|148833508 notch1 preproprotein [Homo sapiens] 34 0.17
gi|112420992 crumbs homolog 2 [Homo sapiens] 34 0.17
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 33 0.22
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 33 0.22
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 33 0.22
gi|115511036 alpha-kinase 3 [Homo sapiens] 33 0.22
gi|24430141 fibrillin 1 precursor [Homo sapiens] 33 0.28
gi|153791171 family with sequence similarity 156, member B [Homo... 33 0.28
gi|31543441 family with sequence similarity 156, member A [Homo ... 33 0.28
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 33 0.37
gi|239753374 PREDICTED: hypothetical protein [Homo sapiens] 33 0.37
gi|239747941 PREDICTED: hypothetical protein XP_002346482 [Homo ... 33 0.37
gi|239741836 PREDICTED: hypothetical protein XP_002342322 [Homo ... 33 0.37
gi|61743978 stabilin 1 precursor [Homo sapiens] 33 0.37
gi|9966841 cell death regulator aven [Homo sapiens] 33 0.37
gi|20336188 paired basic amino acid cleaving system 4 isoform e ... 33 0.37
>gi|47078300 apoptosis related protein 3 isoform b [Homo sapiens]
Length = 284
Score = 595 bits (1533), Expect = e-170
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MKTSAELHEQEKPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHG 60
MKTSAELHEQEKPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHG
Sbjct: 1 MKTSAELHEQEKPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHG 60
Query: 61 PGSLTTLVPWAAALLLALGVERALALPEICTQCPGSVQNLSKVAFYCKTTRELMLHARCC 120
PGSLTTLVPWAAALLLALGVERALALPEICTQCPGSVQNLSKVAFYCKTTRELMLHARCC
Sbjct: 61 PGSLTTLVPWAAALLLALGVERALALPEICTQCPGSVQNLSKVAFYCKTTRELMLHARCC 120
Query: 121 LNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQLQTLILP 180
LNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQLQTLILP
Sbjct: 121 LNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQLQTLILP 180
Query: 181 QHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCAD 240
QHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCAD
Sbjct: 181 QHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCAD 240
Query: 241 GFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS 284
GFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS
Sbjct: 241 GFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS 284
>gi|18105012 apoptosis related protein 3 isoform a [Homo sapiens]
Length = 171
Score = 366 bits (940), Expect = e-101
Identities = 171/171 (100%), Positives = 171/171 (100%)
Query: 114 MLHARCCLNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQ 173
MLHARCCLNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQ
Sbjct: 1 MLHARCCLNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIIDLQANPLKGDLANTFRGFTQ 60
Query: 174 LQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGL 233
LQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGL
Sbjct: 61 LQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGL 120
Query: 234 LQCVCADGFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS 284
LQCVCADGFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS
Sbjct: 121 LQCVCADGFHGYKCMRQGSFSLLMFFGILGATTLSVSILLWATQRRKAKTS 171
>gi|45593147 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 202 QICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
+ C +++C T P C G C+ DG G CVC GFHG C R+
Sbjct: 86 KFCDKDEHICT-TQSP--CQNGGQCMYDGGGEYHCVCLPGFHGRDCERK 131
>gi|45545431 EGF-like-domain, multiple 9 [Homo sapiens]
Length = 383
Score = 41.2 bits (95), Expect = 0.001
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 202 QICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
+ C +++C T P C G C+ DG G CVC GFHG C R+
Sbjct: 86 KFCDKDEHICT-TQSP--CQNGGQCMYDGGGEYHCVCLPGFHGRDCERK 131
>gi|74136023 delta-like 1 homolog [Homo sapiens]
Length = 383
Score = 38.5 bits (88), Expect = 0.007
Identities = 16/51 (31%), Positives = 25/51 (49%), Gaps = 4/51 (7%)
Query: 200 DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
D ++C C++ C NG+CV GL +C CA G+ G C ++
Sbjct: 81 DGELCDRDVRACSSAP----CANNGTCVSLDDGLYECSCAPGYSGKDCQKK 127
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 37.0 bits (84), Expect = 0.020
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 6/69 (8%)
Query: 182 HVNCPGGI--NAWNTIT-SYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVC 238
H C GI W + + Q+C N C G + C G+C GP QC C
Sbjct: 268 HPGCVHGICNEPWQCLCETNWGGQLCDKDLNYC---GTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 239 ADGFHGYKC 247
+G+ G C
Sbjct: 325 PEGYSGPNC 333
Score = 33.9 bits (76), Expect = 0.17
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 200 DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+ IC N C+ P C +G+CV DG +C CA GF G C
Sbjct: 775 EGPICAQNTNDCS----PHPCYNSGTCV-DGDNWYRCECAPGFAGPDC 817
Score = 31.2 bits (69), Expect = 1.1
Identities = 12/35 (34%), Positives = 19/35 (54%), Gaps = 1/35 (2%)
Query: 213 NTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
N + C G+C+ DG +C+C+DG+ G C
Sbjct: 631 NDCESNPCRNGGTCI-DGVNSYKCICSDGWEGAYC 664
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 35.8 bits (81), Expect = 0.044
Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 213 NTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMR 249
N DP C GSC DG G C C GF G +C R
Sbjct: 851 NDCDPNPCLNGGSC-QDGVGSFSCSCLPGFAGPRCAR 886
Score = 31.6 bits (70), Expect = 0.83
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 6/66 (9%)
Query: 185 CPGGINAWN-TITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFH 243
C +N ++ T S CQ + C +T C CV D P +C CA+GF
Sbjct: 484 CKDRVNGFSCTCPSGFSGSTCQLDVDECASTP----CRNGAKCV-DQPDGYECRCAEGFE 538
Query: 244 GYKCMR 249
G C R
Sbjct: 539 GTLCDR 544
Score = 30.4 bits (67), Expect = 1.8
Identities = 14/41 (34%), Positives = 15/41 (36%), Gaps = 3/41 (7%)
Query: 210 LCNNTG---DPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
LC N P C G+C G C C GF G C
Sbjct: 193 LCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNC 233
Score = 29.6 bits (65), Expect = 3.1
Identities = 12/34 (35%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
P C G+CV DG C+C G+ G C +
Sbjct: 930 PSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHE 962
>gi|208431817 protein kinase-like protein SgK493 [Homo sapiens]
Length = 493
Score = 35.8 bits (81), Expect = 0.044
Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 12/78 (15%)
Query: 9 EQEKPPSSPR---ATGPGRLG-------HARGRGPDALRGGAAGPGRASSGAPRERKM-- 56
E +P SP A GPGR G R R + R GPG + R R M
Sbjct: 31 EPPRPGQSPEPSPAPGPGRRGGRGELARQIRARYEEVQRYSRGGPGPGAGRPERRRLMDL 90
Query: 57 APHGPGSLTTLVPWAAAL 74
AP GPG PWA L
Sbjct: 91 APGGPGLPRPRPPWARPL 108
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 34.7 bits (78), Expect = 0.098
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 5/33 (15%)
Query: 220 CPENGSCVPD-----GPGLLQCVCADGFHGYKC 247
C GSCV D G G+ CVC GFHG C
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLC 1215
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 34.7 bits (78), Expect = 0.098
Identities = 21/68 (30%), Positives = 28/68 (41%), Gaps = 23/68 (33%)
Query: 182 HVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADG 241
H++CP G+ N C+NT C G+C+P+ CVCA G
Sbjct: 564 HLSCPEGLWGVN-----------------CSNTCT---CKNGGTCLPENGN---CVCAPG 600
Query: 242 FHGYKCMR 249
F G C R
Sbjct: 601 FRGPSCQR 608
Score = 28.1 bits (61), Expect = 9.1
Identities = 13/41 (31%), Positives = 19/41 (46%), Gaps = 4/41 (9%)
Query: 211 CNNTGDPEMCPENGSCVPD----GPGLLQCVCADGFHGYKC 247
C+ D P NG+C+ + G +C DGF+G C
Sbjct: 319 CDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSC 359
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 34.7 bits (78), Expect = 0.098
Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 203 ICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+C N C G C G+C+ P +C C DG+ G C
Sbjct: 303 LCDKDLNYC---GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Score = 32.0 bits (71), Expect = 0.63
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 5/48 (10%)
Query: 200 DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+ + C N CN P C G CV DG +C CA GF G C
Sbjct: 744 EGRTCTHNTNDCN----PLPCYNGGICV-DGVNWFRCECAPGFAGPDC 786
Score = 31.2 bits (69), Expect = 1.1
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 212 NNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
N++ P C G+CV G C+C DG+ G C
Sbjct: 714 NSSCLPNPCVNGGTCVGSGASF-SCICRDGWEGRTC 748
Score = 29.3 bits (64), Expect = 4.1
Identities = 11/29 (37%), Positives = 14/29 (48%)
Query: 219 MCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+C +G CV G C+C GF G C
Sbjct: 567 VCGPHGRCVSQPGGNFSCICDSGFTGTYC 595
Score = 28.1 bits (61), Expect = 9.1
Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 16/63 (25%)
Query: 185 CPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHG 244
CP W T +D C+GQ C G+C D QCVC GF G
Sbjct: 411 CP---EQWVGATCQLDVNDCRGQ------------CQHGGTC-KDLVNGYQCVCPRGFGG 454
Query: 245 YKC 247
C
Sbjct: 455 RHC 457
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 34.7 bits (78), Expect = 0.098
Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 203 ICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+C N C G C G+C+ P +C C DG+ G C
Sbjct: 303 LCDKDLNYC---GSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Score = 32.0 bits (71), Expect = 0.63
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 5/48 (10%)
Query: 200 DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+ + C N CN P C G CV DG +C CA GF G C
Sbjct: 782 EGRTCTHNTNDCN----PLPCYNGGICV-DGVNWFRCECAPGFAGPDC 824
Score = 31.2 bits (69), Expect = 1.1
Identities = 13/36 (36%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 212 NNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
N++ P C G+CV G C+C DG+ G C
Sbjct: 752 NSSCLPNPCVNGGTCVGSGASF-SCICRDGWEGRTC 786
Score = 29.6 bits (65), Expect = 3.1
Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 13/59 (22%)
Query: 189 INAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
I W I +I+ C+GQ C G+C D QCVC GF G C
Sbjct: 450 IPGWKGINCHINVNDCRGQ------------CQHGGTC-KDLVNGYQCVCPRGFGGRHC 495
Score = 29.3 bits (64), Expect = 4.1
Identities = 11/29 (37%), Positives = 14/29 (48%)
Query: 219 MCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+C +G CV G C+C GF G C
Sbjct: 605 VCGPHGRCVSQPGGNFSCICDSGFTGTYC 633
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 34.7 bits (78), Expect = 0.098
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 5/48 (10%)
Query: 200 DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
D Q C + + C + + C +G+C P PG C C GF G +C
Sbjct: 961 DGQNCSKELDACQS----QPCHNHGTCTPK-PGGFHCACPPGFVGLRC 1003
Score = 32.3 bits (72), Expect = 0.48
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 204 CQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
CQ + + C DP CP SC+ D PG C+C GF G C
Sbjct: 586 CQTEVDEC--LSDP--CPVGASCL-DLPGAFFCLCPSGFTGQLC 624
Score = 32.0 bits (71), Expect = 0.63
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 5/44 (11%)
Query: 204 CQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
CQ + C + C G+CV + PG C+CA GF G +C
Sbjct: 764 CQTSTDYCVSAP----CFNGGTCV-NRPGTFSCLCAMGFQGPRC 802
Score = 31.6 bits (70), Expect = 0.83
Identities = 12/31 (38%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
P C GSC+ + PG C+C G+ G +C
Sbjct: 443 PSPCEHGGSCL-NTPGSFNCLCPPGYTGSRC 472
Score = 30.8 bits (68), Expect = 1.4
Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 5/44 (11%)
Query: 204 CQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
CQ +LC + CP N C+ GP C+C G+ G C
Sbjct: 841 CQTLMDLCAQ----KPCPRNSHCLQTGPS-FHCLCLQGWTGPLC 879
Score = 30.4 bits (67), Expect = 1.8
Identities = 12/31 (38%), Positives = 14/31 (45%), Gaps = 1/31 (3%)
Query: 220 CPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
C G C D PG C C GF G +C +
Sbjct: 560 CANGGQC-QDQPGAFHCKCLPGFEGPRCQTE 589
Score = 30.0 bits (66), Expect = 2.4
Identities = 13/31 (41%), Positives = 15/31 (48%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
PE C G+C+ G C CA GF G C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
Score = 29.6 bits (65), Expect = 3.1
Identities = 14/44 (31%), Positives = 18/44 (40%), Gaps = 2/44 (4%)
Query: 204 CQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
C + C G P C G+C + G CVC G+ G C
Sbjct: 311 CSEDVDECETQGPPH-CRNGGTC-QNSAGSFHCVCVSGWGGTSC 352
Score = 29.6 bits (65), Expect = 3.1
Identities = 19/71 (26%), Positives = 29/71 (40%), Gaps = 15/71 (21%)
Query: 177 LILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQC 236
L+ H CP G+ + Q+C+ + N C + C + C D QC
Sbjct: 493 LLATFHCLCPPGL----------EGQLCEVETNECASAP----CLNHADC-HDLLNGFQC 537
Query: 237 VCADGFHGYKC 247
+C GF G +C
Sbjct: 538 ICLPGFSGTRC 548
Score = 29.6 bits (65), Expect = 3.1
Identities = 14/48 (29%), Positives = 21/48 (43%), Gaps = 5/48 (10%)
Query: 203 ICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
+CQ N C + C +C+ G L C CA G+ G C ++
Sbjct: 926 LCQDHVNPCES----RPCQNGATCMAQPSGYL-CQCAPGYDGQNCSKE 968
Score = 28.5 bits (62), Expect = 7.0
Identities = 11/31 (35%), Positives = 14/31 (45%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
P C + G C G QC C G+ G +C
Sbjct: 124 PSFCSKRGRCHIQASGRPQCSCMPGWTGEQC 154
>gi|28269693 xylosyltransferase I [Homo sapiens]
Length = 959
Score = 34.3 bits (77), Expect = 0.13
Identities = 26/59 (44%), Positives = 29/59 (49%), Gaps = 6/59 (10%)
Query: 14 PSSPRATGPGRLGHARGRGPDA-LRGGAAGPGR----ASSGAPRERKMAPHGPGSLTTL 67
P++ R G G G GRGP A RGG G R AS GA R + PH P L TL
Sbjct: 74 PAAARGGGGGGGGGGGGRGPQARARGGGPGEPRGQQPASRGALPARALDPH-PSPLITL 131
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 33.9 bits (76), Expect = 0.17
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 6/64 (9%)
Query: 185 CPGGINAWNTITSY-IDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFH 243
C GIN++ + CQ N C D + C G+C DG G +C C G+
Sbjct: 998 CVDGINSFTCLCPPGFTGSYCQHDVNEC----DSQPCLHGGTC-QDGCGSYRCTCPQGYT 1052
Query: 244 GYKC 247
G C
Sbjct: 1053 GPNC 1056
Score = 32.3 bits (72), Expect = 0.48
Identities = 12/31 (38%), Positives = 14/31 (45%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
P C G+C P G +C C GF G C
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254
Score = 31.6 bits (70), Expect = 0.83
Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 5/45 (11%)
Query: 203 ICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+CQ + C +T C C+ DGP CVC +G+ G C
Sbjct: 524 LCQYDVDECASTP----CKNGAKCL-DGPNTYTCVCTEGYTGTHC 563
Score = 31.2 bits (69), Expect = 1.1
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 5/48 (10%)
Query: 204 CQGQKNLCNNTGDP----EMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
C+ + CN DP C NG+CV D G C C GF G +C
Sbjct: 1218 CEINVDDCNPPVDPVSRSPKCFNNGTCV-DQVGGYSCTCPPGFVGERC 1264
Score = 30.0 bits (66), Expect = 2.4
Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 185 CPGGINAWNTITSYIDNQICQGQKNLC-NNTGD--PEMCPENGSCVPDGPGLLQCVCADG 241
C G N + + SY C NNT D C G+CV DG C+C G
Sbjct: 954 CRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV-DGINSFTCLCPPG 1012
Query: 242 FHGYKC 247
F G C
Sbjct: 1013 FTGSYC 1018
Score = 28.5 bits (62), Expect = 7.0
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 216 DPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
DP+ C GSC DG C+C G+ G+ C
Sbjct: 571 DPDPC-HYGSC-KDGVATFTCLCRPGYTGHHC 600
Score = 28.1 bits (61), Expect = 9.1
Identities = 12/34 (35%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQ 250
P C +NG+ D G C C G+HG C +
Sbjct: 1151 PSPC-QNGATCTDYLGGYSCKCVAGYHGVNCSEE 1183
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 33.9 bits (76), Expect = 0.17
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 220 CPENGSCVPDGPGLLQCVCADGFHGYKC 247
C GSC+ DG G +CVCA G+ G +C
Sbjct: 155 CLHGGSCL-DGVGSFRCVCAPGYGGTRC 181
Score = 29.3 bits (64), Expect = 4.1
Identities = 12/30 (40%), Positives = 14/30 (46%), Gaps = 2/30 (6%)
Query: 220 CPENGSCVPDGPGL--LQCVCADGFHGYKC 247
C CVP GP +C C GF G +C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRC 105
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 33.5 bits (75), Expect = 0.22
Identities = 33/131 (25%), Positives = 50/131 (38%), Gaps = 12/131 (9%)
Query: 11 EKPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPW 70
E+ R +G G R P+ +R AAG RA+ GAP P P +++ +
Sbjct: 19 ERRSKRRRRSGGDGGGGGGARAPEGVRAPAAGQPRATKGAPPPPGTPP--PSPMSSAIER 76
Query: 71 AAALLLALGVERALALPEICTQCPGSVQNLSKVAFYCKTTRELMLHARCCLNQKGTILGL 130
+ V+ L +P C G QN+ ++ K + H C L
Sbjct: 77 KSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGD-RYFLKAIDQYW-HEDC--------LSC 126
Query: 131 DLQNCSLEDPG 141
DL C L + G
Sbjct: 127 DLCGCRLGEVG 137
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 33.5 bits (75), Expect = 0.22
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 12 KPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPWA 71
+PP +P P G RG G G ++GPG + PR R++ P G + T V
Sbjct: 2460 QPPPAPPPPPPPADGGPRGAGDPGGAGASSGPG--APAEPRVREVWPRGLITYVT-VTEP 2516
Query: 72 AALLLALGVERALAL 86
+A+L+ GV L +
Sbjct: 2517 SAVLVVRGVRDRLVI 2531
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 33.5 bits (75), Expect = 0.22
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 2/54 (3%)
Query: 209 NLCNNTGD--PEMCPENGSCVPDGPGLLQCVCADGFHGYKCMRQGSFSLLMFFG 260
N CN + +C C+PD C+C G+ G C + SFS F G
Sbjct: 2908 NTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFSTAKFMG 2961
Score = 31.2 bits (69), Expect = 1.1
Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%)
Query: 202 QICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
Q C + NLC+ +P C N +C+ C+C + F G C
Sbjct: 844 QFCHQRYNLCDLLHNP--CRNNSTCLALVDANQHCICREEFEGKNC 887
Score = 29.6 bits (65), Expect = 3.1
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 6/41 (14%)
Query: 212 NNTGDPEM----CPENGSCVPDGPG-LLQCVCADGFHGYKC 247
+N +PE+ C G CV DGPG C C GF G C
Sbjct: 1119 DNCAEPELNSVICLNGGICV-DGPGHTFDCRCLPGFSGQFC 1158
>gi|115511036 alpha-kinase 3 [Homo sapiens]
Length = 1907
Score = 33.5 bits (75), Expect = 0.22
Identities = 24/81 (29%), Positives = 32/81 (39%)
Query: 9 EQEKPPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLV 68
E E P P G + GR +A A G G ++ +E PG T +
Sbjct: 1294 EGEVSPEGPGLLGASQESSMAGRLGEAGGQAAPGQGPSAESIAQEPSQEEKFPGEALTGL 1353
Query: 69 PWAAALLLALGVERALALPEI 89
P A LALG R LP++
Sbjct: 1354 PAATPEELALGARRKRFLPKV 1374
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 33.1 bits (74), Expect = 0.28
Identities = 38/139 (27%), Positives = 47/139 (33%), Gaps = 40/139 (28%)
Query: 105 FYCKTTRELMLHARCCLNQKGTILGLDLQNCS-LEDPGPNFHQAHTTVIIDLQANPLKGD 163
F CK T + C KG IL D ++C L++ H +
Sbjct: 2457 FICKNTEG----SYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCV----------- 2501
Query: 164 LANTFRGFTQLQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPEN 223
NT GFT CP G +T S IDN C NLC + G +C
Sbjct: 2502 --NTIGGFT----------CKCPPGFTQHHT--SCIDNNECTSDINLCGSKG---ICQNT 2544
Query: 224 GSCVPDGPGLLQCVCADGF 242
PG C C GF
Sbjct: 2545 -------PGSFTCECQRGF 2556
Score = 28.9 bits (63), Expect = 5.4
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 11/59 (18%)
Query: 185 CPGGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFH 243
CP G I++ ID C+ +LC NG CV + G QC C G+H
Sbjct: 1140 CPPGHQLSPNISACIDINECELSAHLC----------PNGRCV-NLIGKYQCACNPGYH 1187
Score = 28.1 bits (61), Expect = 9.1
Identities = 36/149 (24%), Positives = 49/149 (32%), Gaps = 43/149 (28%)
Query: 103 VAFYCKTTRELMLHARC--------CLNQKGTILGLDLQNCSLEDPGPNFHQAHTTVIID 154
V YC+ R L + RC C KG LDL+ ++ + +
Sbjct: 449 VTDYCQLVRYLCQNGRCIPTPGSCRCECNKG--FQLDLRGECID-------------VDE 493
Query: 155 LQANPLKGDLANTFRGFTQLQTLILPQHVNCPGGINAWNTITSYIDNQICQGQKNLCNNT 214
+ NP G +G Q C G + T T D C +CNN
Sbjct: 494 CEKNPCAGGECINNQGSYTCQ---------CRAGYQSTLTRTECRDIDECLQNGRICNN- 543
Query: 215 GDPEMCPENGSCVPDGPGLLQCVCADGFH 243
G C+ + G CVC GFH
Sbjct: 544 ---------GRCI-NTDGSFHCVCNAGFH 562
>gi|153791171 family with sequence similarity 156, member B [Homo
sapiens]
Length = 213
Score = 33.1 bits (74), Expect = 0.28
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 48 SGAPRERKMAPHGPGSLTTLVPWAAALLLALGVERALALPEICTQ 92
SG P E APH P S TLV + L L+LG + LPE Q
Sbjct: 139 SGIPGESNRAPH-PSSWETLVQGLSGLTLSLGTNQPGPLPEAALQ 182
>gi|31543441 family with sequence similarity 156, member A [Homo
sapiens]
Length = 213
Score = 33.1 bits (74), Expect = 0.28
Identities = 20/45 (44%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 48 SGAPRERKMAPHGPGSLTTLVPWAAALLLALGVERALALPEICTQ 92
SG P E APH P S TLV + L L+LG + LPE Q
Sbjct: 139 SGIPGESNRAPH-PSSWETLVQGLSGLTLSLGTNQPGPLPEAALQ 182
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 32.7 bits (73), Expect = 0.37
Identities = 12/28 (42%), Positives = 15/28 (53%)
Query: 220 CPENGSCVPDGPGLLQCVCADGFHGYKC 247
C +C+P G QC+C DGF G C
Sbjct: 4113 CQHGATCMPAGEYEFQCLCRDGFKGDLC 4140
>gi|239753374 PREDICTED: hypothetical protein [Homo sapiens]
Length = 154
Score = 32.7 bits (73), Expect = 0.37
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 15 SSPRATGPGRLGH--ARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPWAA 72
S PR G GR+G + + GG GP RA+ G + + P + V AA
Sbjct: 71 SLPRRAGRGRVGQWLLQPGSCCSRSGGCCGPARAAPGLRAD--VLPRSAAAQAVAVAVAA 128
Query: 73 ALL-LALGVERALALPEICTQCP 94
A + +A R A PE+ CP
Sbjct: 129 AAVEVARATARPGAAPELSNSCP 151
>gi|239747941 PREDICTED: hypothetical protein XP_002346482 [Homo
sapiens]
Length = 154
Score = 32.7 bits (73), Expect = 0.37
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 15 SSPRATGPGRLGH--ARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPWAA 72
S PR G GR+G + + GG GP RA+ G + + P + V AA
Sbjct: 71 SLPRRAGRGRVGQWLLQPGSCCSRSGGCCGPARAAPGLRAD--VLPRSAAAQAVAVAVAA 128
Query: 73 ALL-LALGVERALALPEICTQCP 94
A + +A R A PE+ CP
Sbjct: 129 AAVEVARATARPGAAPELSNSCP 151
>gi|239741836 PREDICTED: hypothetical protein XP_002342322 [Homo
sapiens]
Length = 154
Score = 32.7 bits (73), Expect = 0.37
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 15 SSPRATGPGRLGH--ARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPWAA 72
S PR G GR+G + + GG GP RA+ G + + P + V AA
Sbjct: 71 SLPRRAGRGRVGQWLLQPGSCCSRSGGCCGPARAAPGLRAD--VLPRSAAAQAVAVAVAA 128
Query: 73 ALL-LALGVERALALPEICTQCP 94
A + +A R A PE+ CP
Sbjct: 129 AAVEVARATARPGAAPELSNSCP 151
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 32.7 bits (73), Expect = 0.37
Identities = 17/58 (29%), Positives = 23/58 (39%), Gaps = 1/58 (1%)
Query: 187 GGINAWNTITSYIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHG 244
GG+ T + C C TG + C + CV G+ +C C DGF G
Sbjct: 798 GGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQHCHLHARCVSQ-EGVARCRCLDGFEG 854
Score = 32.7 bits (73), Expect = 0.37
Identities = 12/28 (42%), Positives = 14/28 (50%)
Query: 217 PEMCPENGSCVPDGPGLLQCVCADGFHG 244
P C N +CV D G C CA G+ G
Sbjct: 1421 PRKCDPNANCVQDSAGASTCACAAGYSG 1448
Score = 32.3 bits (72), Expect = 0.48
Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 182 HVNCPGGINAWNTIT---SYI-DNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCV 237
H NC T T Y+ D ++CQ + + G C + C+P GP + C
Sbjct: 1469 HANCTKVAPGQRTCTCQDGYMGDGELCQEINSCLIHHGG---CHIHAECIPTGPQQVSCS 1525
Query: 238 CADGFHG 244
C +G+ G
Sbjct: 1526 CREGYSG 1532
Score = 29.6 bits (65), Expect = 3.1
Identities = 37/167 (22%), Positives = 52/167 (31%), Gaps = 22/167 (13%)
Query: 90 CTQCPGSVQNLSKVAFYCKTTRELMLHARCCLNQKGTILGLDLQNCSLEDP---GPNFHQ 146
C +CPG + C + C N +G+ Q C +DP GP+
Sbjct: 109 CHECPGGAETPCNGHGTCLDGMDRNGTCVCQENFRGSAC----QEC--QDPNRFGPDCQS 162
Query: 147 AHTTVIIDLQANPLKGDLANTFRGFTQ---------LQTLILPQHVNCPGGINAWNTITS 197
+ V P F G+T Q L PQ+ C + +
Sbjct: 163 VCSCVHGVCNHGPRGDGSCLCFAGYTGPHCDQELPVCQELRCPQNTQCSAEAPSCRCLPG 222
Query: 198 YIDNQICQGQKNLCNNTGDPEMCPENGSCVPDGPGLLQCVCADGFHG 244
Y QG + N P C C G QC C + +HG
Sbjct: 223 YTQ----QGSECRAPNPCWPSPCSLLAQCSVSPKGQAQCHCPENYHG 265
Score = 29.6 bits (65), Expect = 3.1
Identities = 12/33 (36%), Positives = 15/33 (45%)
Query: 215 GDPEMCPENGSCVPDGPGLLQCVCADGFHGYKC 247
G C + G C+ G QC+C GF G C
Sbjct: 1974 GPSSPCSDRGVCMDGMSGSGQCLCRSGFAGTAC 2006
Score = 29.3 bits (64), Expect = 4.1
Identities = 11/25 (44%), Positives = 12/25 (48%)
Query: 220 CPENGSCVPDGPGLLQCVCADGFHG 244
C EN CVP G C C G+ G
Sbjct: 873 CSENAECVPGSLGTHHCTCHKGWSG 897
Score = 28.1 bits (61), Expect = 9.1
Identities = 11/29 (37%), Positives = 15/29 (51%)
Query: 219 MCPENGSCVPDGPGLLQCVCADGFHGYKC 247
+C +G C G +C C +GFHG C
Sbjct: 1339 VCSGHGQCQDRFLGSGECHCHEGFHGTAC 1367
>gi|9966841 cell death regulator aven [Homo sapiens]
Length = 362
Score = 32.7 bits (73), Expect = 0.37
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 21 GPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGS 63
G GR G RGRG RG GR GAPR + P G G+
Sbjct: 47 GGGRRGRGRGRGFRGARG-----GRGGGGAPRGSRREPGGWGA 84
>gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
Length = 623
Score = 32.7 bits (73), Expect = 0.37
Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 13 PPSSPRATGPGRLGHARGRGPDALRGGAAGPGRASSGAPRERKMAPHGPGSLTTLVPWAA 72
PP +P A GP A A G AG G +G P R +AP PW
Sbjct: 2 PPRAPPAPGPRPPPRAAAATDTAAGAGGAG-GAGGAGGPGFRPLAPR---------PWRW 51
Query: 73 ALLLAL 78
LLLAL
Sbjct: 52 LLLLAL 57
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,784,540
Number of Sequences: 37866
Number of extensions: 751806
Number of successful extensions: 4594
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 4037
Number of HSP's gapped (non-prelim): 757
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.