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Search of human proteins with 4557853
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557853 transcription factor SOX9 [Homo sapiens]
(509 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557853 transcription factor SOX9 [Homo sapiens] 1066 0.0
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 493 e-139
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 385 e-107
gi|11967991 SRY-box 17 [Homo sapiens] 139 8e-33
gi|8924248 SRY-box 18 [Homo sapiens] 128 1e-29
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 124 3e-28
gi|5902108 SRY-box 21 [Homo sapiens] 122 1e-27
gi|13899269 SRY-box 7 [Homo sapiens] 121 2e-27
gi|4759162 SRY-box 14 [Homo sapiens] 120 2e-27
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 120 4e-27
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 119 7e-27
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 119 7e-27
gi|5902106 SRY-box 15 [Homo sapiens] 115 9e-26
gi|4507161 SRY-box 11 [Homo sapiens] 115 1e-25
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 110 2e-24
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 109 5e-24
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 109 5e-24
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 109 5e-24
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 105 7e-23
gi|41406089 SRY-box 13 [Homo sapiens] 100 4e-21
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 97 3e-20
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 97 3e-20
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 97 3e-20
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 97 3e-20
gi|4507225 sex determining region Y [Homo sapiens] 96 8e-20
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 86 6e-17
gi|112421108 capicua homolog [Homo sapiens] 76 6e-14
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 73 7e-13
gi|71143137 high-mobility group box 3 [Homo sapiens] 63 7e-10
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 60 6e-09
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 1066 bits (2757), Expect = 0.0
Identities = 509/509 (100%), Positives = 509/509 (100%)
Query: 1 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL 60
MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
Sbjct: 1 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL 60
Query: 61 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR 120
KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
Sbjct: 61 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR 120
Query: 121 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK 180
RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
Sbjct: 121 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK 180
Query: 181 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT 240
SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT
Sbjct: 181 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT 240
Query: 241 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP 300
PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP
Sbjct: 241 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP 300
Query: 301 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP 360
NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP
Sbjct: 301 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP 360
Query: 361 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY 420
QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY
Sbjct: 361 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY 420
Query: 421 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI 480
SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI
Sbjct: 421 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI 480
Query: 481 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP 509
ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
Sbjct: 481 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP 509
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 493 bits (1269), Expect = e-139
Identities = 273/502 (54%), Positives = 324/502 (64%), Gaps = 58/502 (11%)
Query: 13 EQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVC 72
E+ + LS +P++ D G GSG + K + D E+++DKFPVC
Sbjct: 18 EEPRCLSPGSAPSLGPDGGGG----GSGLRASPGPGELGKVKKEQQD--GEADDDKFPVC 71
Query: 73 IREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHN 132
IREAVSQVL GYDWTLVPMPVRVNG+SK+KPHVKRPMNAFMVWAQAARRKLADQYPHLHN
Sbjct: 72 IREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHN 131
Query: 133 AELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAE-- 190
AELSKTLGKLWRLLNES+KRPF+EEAERLR+QHKKDHPDYKYQPRRRK+ K Q EAE
Sbjct: 132 AELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECP 191
Query: 191 --EATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEH-SGQSQGPPTPPTTPKTDVQP 247
EA + + A +K+ D H G EH SGQS GPPTPPTTPKT++Q
Sbjct: 192 GGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKTELQS 251
Query: 248 GKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVP 307
GKAD KR+GR + EGG+ P IDF +VDIGE+S +V+SN+ETFDV E DQYLPPNGHPG
Sbjct: 252 GKADPKRDGRSMGEGGK-PHIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNGHPG-- 308
Query: 308 ATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPP 367
H YG+ S A AS W+SK PP P +PP A Q +
Sbjct: 309 --HVSSYSAAGYGLGSALAV-ASGHSAWISK----PPGVALPTVSPPGVDAKAQVKT--- 358
Query: 368 QQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPH 427
A PQ P HY++Q S QIAY+ +LPH
Sbjct: 359 --ETAGPQ---------------------------GPPHYTDQP--STSQIAYTSLSLPH 387
Query: 428 YSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVP 487
Y ++P I+R Q+DY+DHQ S YY H +GQ +GLYS F+YM P+QRP+YT I+D S P
Sbjct: 388 YGSAFPSISRPQFDYSDHQPSGPYYGH-SGQASGLYSAFSYMGPSQRPLYTAISDPS--P 444
Query: 488 SIPQTHSPQHWEQPVYTQLTRP 509
S PQ+HSP HWEQPVYT L+RP
Sbjct: 445 SGPQSHSPTHWEQPVYTTLSRP 466
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 385 bits (990), Expect = e-107
Identities = 237/495 (47%), Positives = 288/495 (58%), Gaps = 73/495 (14%)
Query: 21 APSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQV 80
A S + EDS PS +GS+ +G+P E+ +++FP CIR+AVSQV
Sbjct: 19 ASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDP---AEAADERFPACIRDAVSQV 75
Query: 81 LKGYDWTLVPMPVRVNGSS--KNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT 138
LKGYDW+LVPMPVR G K KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT
Sbjct: 76 LKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKT 135
Query: 139 LGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATE-QTH 197
LGKLWRLL+ESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS K G ++++ E H
Sbjct: 136 LGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPH 195
Query: 198 ISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQP--GKADLKRE 255
A++KA +G+ + H G+H+GQ+ GPPTPPTTPKT++Q K +LK E
Sbjct: 196 PGGGAVYKA--------EAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQQAGAKPELKLE 247
Query: 256 GRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTY 315
GR + GRQ IDF +VDI ELSS+V+ ++ FDV+EFDQYLP G P GQ Y
Sbjct: 248 GRRPVDSGRQ-NIDFSNVDISELSSEVMGTMDAFDVHEFDQYLPLGG--PAPPEPGQ-AY 303
Query: 316 TGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQ 375
G+Y A A VW K AP A P P +P
Sbjct: 304 GGAY-------FHAGASPVWAHKS---------------APSASASPTETGPPRP----- 336
Query: 376 QPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPI 435
HIKTEQ SP HY +Q + SP + S + + P
Sbjct: 337 --------------------HIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGPF 376
Query: 436 TRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSP 495
SQ DY D Q +SSYY G GLY + +P +RP +P+ + ++P HSP
Sbjct: 377 AGSQGDYGDLQ-ASSYYGAYPGYAPGLYQYPCFHSP-RRPYASPLLNGL---ALPPAHSP 431
Query: 496 -QHWEQPVYTQLTRP 509
HW+QPVYT LTRP
Sbjct: 432 TSHWDQPVYTTLTRP 446
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 139 bits (349), Expect = 8e-33
Identities = 106/309 (34%), Positives = 133/309 (43%), Gaps = 40/309 (12%)
Query: 92 PVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEK 151
P G +K + ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L +EK
Sbjct: 55 PAGAAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEK 114
Query: 152 RPFVEEAERLRVQHKKDHPDYKYQPRRRKSVK----------NGQAEAEEAT---EQTHI 198
RPFVEEAERLRVQH +DHP+YKY+PRRRK VK +G AE + A E +
Sbjct: 115 RPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGFLHGLAEPQAAALGPEGGRV 174
Query: 199 SPNAIFKALQADS---------PHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGK 249
+ + + PH + S G PTP T+P V P
Sbjct: 175 AMDGLGLQFPEQGFPAGPPLLPPHMGGHYRDCQSLGAPPLDGYPLPTPDTSPLDGVDPDP 234
Query: 250 ADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVP-- 307
A P+P G + + SD E + P P +P
Sbjct: 235 AFF---AAPMP-GDCPAAGTYSYAQV----SDYAGPPEPPAGPMHPRLGPEPAGPSIPGL 286
Query: 308 -----ATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQP 362
A H GS G H + Q PP P QP P P+A P
Sbjct: 287 LAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQHQHHPPGPGQP---SPPPEALPCR 343
Query: 363 QAAPPQQPA 371
P QPA
Sbjct: 344 DGTDPSQPA 352
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 128 bits (321), Expect = 1e-29
Identities = 92/273 (33%), Positives = 123/273 (45%), Gaps = 45/273 (16%)
Query: 101 NKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAER 160
++ ++RPMNAFMVWA+ R++LA Q P LHNA LSK LGK W+ LN +EKRPFVEEAER
Sbjct: 81 DESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAER 140
Query: 161 LRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQADSP-----HSS 215
LRVQH +DHP+YKY+PRR+K +A + + P + L P ++
Sbjct: 141 LRVQHLRDHPNYKYRPRRKK----------QARKARRLEPGLLLPGLAPPQPPPEPFPAA 190
Query: 216 SGMSEVH---SPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRD 272
SG + P G PTP +P ++PG+A PP D
Sbjct: 191 SGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAF-----------FPPPAAPED 239
Query: 273 VDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAG 332
+ + + D P G G P T + AA A
Sbjct: 240 CALRPFRAPYAPTELSRD---------PGGCYGAPLAEALRT-------APPAAPLAGLY 283
Query: 333 HVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAA 365
+ + P P PP+APP A P AA
Sbjct: 284 YGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAA 316
Score = 31.2 bits (69), Expect = 2.3
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 352 APPAPQAPPQPQAAPPQQP 370
AP AP +PP PQ +PP+ P
Sbjct: 44 APAAPASPPSPQRSPPRSP 62
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 124 bits (310), Expect = 3e-28
Identities = 96/336 (28%), Positives = 139/336 (41%), Gaps = 57/336 (16%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G+ N+ VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W++++E+EKRPF++
Sbjct: 43 GAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFID 102
Query: 157 EAERLRVQHKKDHPDYKYQPRRRK---------SVKNGQAEA------EEATEQTHISPN 201
EA+RLR H K+HPDYKY+PRR+ S+ G A +
Sbjct: 103 EAKRLRALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVG 162
Query: 202 AIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQ---------PGKADL 252
A + +SP ++G H G +G G +Q PG
Sbjct: 163 AAAVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGA 222
Query: 253 KREGRPL------PEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGV 306
P P P D+G L ISN + + P+G+ G+
Sbjct: 223 HPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGY------MSASPSGYGGL 276
Query: 307 P-------ATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAP 359
P A + S ++ AA AS+G + P PP AP +AP
Sbjct: 277 PYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPP-APAHSRAP 335
Query: 360 -------------PQPQAAPPQQPAAPPQQPQAHTL 382
P + P AA Q + H+L
Sbjct: 336 CPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHSL 371
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 122 bits (305), Expect = 1e-27
Identities = 53/81 (65%), Positives = 67/81 (82%)
Query: 99 SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158
SK HVKRPMNAFMVW++A RRK+A + P +HN+E+SK LG W+LL ESEKRPF++EA
Sbjct: 2 SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61
Query: 159 ERLRVQHKKDHPDYKYQPRRR 179
+RLR H K+HPDYKY+PRR+
Sbjct: 62 KRLRAMHMKEHPDYKYRPRRK 82
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 121 bits (303), Expect = 2e-27
Identities = 103/335 (30%), Positives = 140/335 (41%), Gaps = 41/335 (12%)
Query: 90 PMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNES 149
P R G ++ ++RPMNAFMVWA+ R++LA Q P LHNAELSK LGK W+ L S
Sbjct: 30 PAVPRPPGDKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLS 89
Query: 150 EKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQA 209
+KRP+V+EAERLR+QH +D+P+YKY+PRR+K K + + +S + AL
Sbjct: 90 QKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQ--NALPE 147
Query: 210 DSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPID 269
S + E GE+S + P + G P G PP
Sbjct: 148 KRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPP-- 205
Query: 270 FRDVDIGELSS-DVISNIETFDVNEFDQYLPPNGHP-GVPATHGQVTYTGSYGISSTAAT 327
E+S DV+ +TF + + +GHP +P G Y+ Y A +
Sbjct: 206 -------EMSPLDVLEPEQTFFSSPCQE---EHGHPRRIPHLPGH-PYSPEY-----APS 249
Query: 328 PASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQ--------------QPAAP 373
P H S P P P PP P P Q + P
Sbjct: 250 PLHCSHPLGSLALGQSPGVS---MMSPVPGCPPSPAYYSPATYHPLHSNLQAHLGQLSPP 306
Query: 374 PQQPQAHTLTTLSSEP--GQSQRTHIKTEQLSPSH 406
P+ P L LS G R +P H
Sbjct: 307 PEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGH 341
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 8/94 (8%)
Query: 234 PPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNE 293
PP+P P ++L+ L P D D +LS + + D NE
Sbjct: 278 PPSPAYYSPATYHPLHSNLQAHLGQLSPPPEHPGFDALD----QLSQ--VELLGDMDRNE 331
Query: 294 FDQYLPPNGHPGVPATHGQVTYTGSYGISSTAAT 327
FDQYL GHP + G + +G +S T
Sbjct: 332 FDQYLNTPGHP--DSATGAMALSGHVPVSQVTPT 363
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 120 bits (302), Expect = 2e-27
Identities = 50/81 (61%), Positives = 68/81 (83%)
Query: 99 SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158
SK H+KRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL+E+EKRP+++EA
Sbjct: 2 SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61
Query: 159 ERLRVQHKKDHPDYKYQPRRR 179
+RLR QH K+HPDYKY+PRR+
Sbjct: 62 KRLRAQHMKEHPDYKYRPRRK 82
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 120 bits (300), Expect = 4e-27
Identities = 69/171 (40%), Positives = 88/171 (51%), Gaps = 39/171 (22%)
Query: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
H+KRPMNAFMVW+Q RRK+ DQ+P +HNAE+SK LG+ W+LL +SEK PFV EAERLR+
Sbjct: 39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98
Query: 164 QHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHS 223
+H D+PDYKY+PR++ K A+A
Sbjct: 99 KHMADYPDYKYRPRKKS--KGAPAKARP------------------------------RP 126
Query: 224 PGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVD 274
PG G S+ P P PG+ + G PL G P D D D
Sbjct: 127 PGGSGGGSRLKPGPQL-------PGRGGRRAAGGPLGGGAAAPEDDDEDDD 170
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 119 bits (298), Expect = 7e-27
Identities = 52/84 (61%), Positives = 69/84 (82%), Gaps = 1/84 (1%)
Query: 97 GSSKNKP-HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFV 155
G+ KN P VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL+E+EKRPF+
Sbjct: 32 GNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFI 91
Query: 156 EEAERLRVQHKKDHPDYKYQPRRR 179
+EA+RLR H K+HPDYKY+PRR+
Sbjct: 92 DEAKRLRALHMKEHPDYKYRPRRK 115
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 119 bits (298), Expect = 7e-27
Identities = 53/89 (59%), Positives = 70/89 (78%), Gaps = 2/89 (2%)
Query: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
H+KRPMNAFMVW+Q RRK+ +Q P +HNAE+SK LGK W+LL +S+K PF+ EAERLR+
Sbjct: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
Query: 164 QHKKDHPDYKYQPRRRKSVKNGQAEAEEA 192
+H D+PDYKY+P RK VK+G A + +
Sbjct: 118 KHMADYPDYKYRP--RKKVKSGNANSSSS 144
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 115 bits (288), Expect = 9e-26
Identities = 50/75 (66%), Positives = 64/75 (85%)
Query: 105 VKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQ 164
VKRPMNAFMVW+ A RR++A Q P +HN+E+SK LG W+LL+E EKRPFVEEA+RLR +
Sbjct: 49 VKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRAR 108
Query: 165 HKKDHPDYKYQPRRR 179
H +D+PDYKY+PRR+
Sbjct: 109 HLRDYPDYKYRPRRK 123
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 115 bits (287), Expect = 1e-25
Identities = 50/94 (53%), Positives = 73/94 (77%), Gaps = 1/94 (1%)
Query: 104 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
H+KRPMNAFMVW++ RRK+ +Q P +HNAE+SK LGK W++L +SEK PF+ EAERLR+
Sbjct: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
Query: 164 QHKKDHPDYKYQPRRR-KSVKNGQAEAEEATEQT 196
+H D+PDYKY+PR++ K + + A ++ E++
Sbjct: 108 KHMADYPDYKYRPRKKPKMDPSAKPSASQSPEKS 141
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 110 bits (276), Expect = 2e-24
Identities = 47/83 (56%), Positives = 66/83 (79%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G ++ VKRPMNAFMVW++ RRK+A + P +HN+E+SK LG W+LL ++EKRPF++
Sbjct: 131 GGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 190
Query: 157 EAERLRVQHKKDHPDYKYQPRRR 179
EA+RLR H K++PDYKY+PRR+
Sbjct: 191 EAKRLRAVHMKEYPDYKYRPRRK 213
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 109 bits (273), Expect = 5e-24
Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 18/165 (10%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G N+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ E
Sbjct: 162 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 221
Query: 157 EAERLRVQHKKDHPDYKYQPRRR-------KSVKNGQAEA------EEATEQTHISPNAI 203
E RL QH + +PDYKY+PR + K ++ G+ +A +E + ++ A
Sbjct: 222 EQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQ 281
Query: 204 FKALQADSPH----SSSGMSEVHSPGEHSGQSQGP-PTPPTTPKT 243
A + + +GM H P EHS S P P P T
Sbjct: 282 IPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQST 326
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 109 bits (273), Expect = 5e-24
Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 18/165 (10%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G N+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ E
Sbjct: 535 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 594
Query: 157 EAERLRVQHKKDHPDYKYQPRRR-------KSVKNGQAEA------EEATEQTHISPNAI 203
E RL QH + +PDYKY+PR + K ++ G+ +A +E + ++ A
Sbjct: 595 EQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQ 654
Query: 204 FKALQADSPH----SSSGMSEVHSPGEHSGQSQGP-PTPPTTPKT 243
A + + +GM H P EHS S P P P T
Sbjct: 655 IPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQST 699
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 109 bits (273), Expect = 5e-24
Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 18/165 (10%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G N+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ E
Sbjct: 548 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 607
Query: 157 EAERLRVQHKKDHPDYKYQPRRR-------KSVKNGQAEA------EEATEQTHISPNAI 203
E RL QH + +PDYKY+PR + K ++ G+ +A +E + ++ A
Sbjct: 608 EQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQ 667
Query: 204 FKALQADSPH----SSSGMSEVHSPGEHSGQSQGP-PTPPTTPKT 243
A + + +GM H P EHS S P P P T
Sbjct: 668 IPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQST 712
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 105 bits (263), Expect = 7e-23
Identities = 109/390 (27%), Positives = 158/390 (40%), Gaps = 76/390 (19%)
Query: 98 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEE 157
S HVKRPMNAFMVWA+ R LA P +NAE+S LG W L+E +K+P+ +E
Sbjct: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
Query: 158 AERLRVQHKKDHPDYKYQPR--RRKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSS 215
A++++ +H+++ P + YQPR +RK + T Q IS N SP S
Sbjct: 390 AQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPT-TVYPYRSPTYS 448
Query: 216 SGMSEVHSPGEHSGQSQGP----PTPPT---TPKTDVQP---GKADLKREGRPLPEGGRQ 265
+ + +P H P PTP +P T QP A + + LP
Sbjct: 449 VVIPSLQNPITHPVGETSPAIQLPTPAVQSPSPVTLFQPSVSSAAQVAVQDPSLPVYPAL 508
Query: 266 PPIDF---RDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGIS 322
PP F D +L S+ ++ Q P V+ + IS
Sbjct: 509 PPQRFTGPSQTDTHQLHSEATHTVK--------QPTP-------------VSLESANRIS 547
Query: 323 STAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTL 382
S+A+T A A + Q PP++ P P++ P PQA+P P P H
Sbjct: 548 SSAST-AHARFATSTIQ-----PPREYSSVSPCPRSAPIPQASPIPHPHVYQPPPLGHPA 601
Query: 383 TTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNL--PHYSPSYP-PITRSQ 439
T + P S + P+ L PHY PS P +R
Sbjct: 602 TLFGTPPRFS--------------------------FHHPYFLPGPHYFPSSTCPYSRPP 635
Query: 440 YDYTDHQNSS----SYYSHAAGQGTGLYST 465
+ Y + +S SYY + G++ST
Sbjct: 636 FGYGNFPSSMPECLSYYEDRYPKHEGIFST 665
Score = 31.2 bits (69), Expect = 2.3
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 339 QQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIK 398
++A P PP QP PAP PP P AA P + TL+ +S S
Sbjct: 2 ERARPEPPPQPRPLRPAP--PPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAV 59
Query: 399 TEQLSPSHYSEQQQHSPQQIAYSP 422
L P+ Q P+Q+ P
Sbjct: 60 ASGLQPA-VRRLLQVKPEQVLLLP 82
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 100 bits (248), Expect = 4e-21
Identities = 41/83 (49%), Positives = 59/83 (71%)
Query: 99 SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158
S+N H+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ EE
Sbjct: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477
Query: 159 ERLRVQHKKDHPDYKYQPRRRKS 181
RL QH + +PDYKY+PR +++
Sbjct: 478 ARLSRQHLEKYPDYKYKPRPKRT 500
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 97.4 bits (241), Expect = 3e-20
Identities = 39/85 (45%), Positives = 61/85 (71%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G + ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ E
Sbjct: 626 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 685
Query: 157 EAERLRVQHKKDHPDYKYQPRRRKS 181
E RL H + +P+YKY+PR +++
Sbjct: 686 EQARLSKIHLEKYPNYKYKPRPKRT 710
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 97.4 bits (241), Expect = 3e-20
Identities = 39/85 (45%), Positives = 61/85 (71%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G + ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ E
Sbjct: 586 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 645
Query: 157 EAERLRVQHKKDHPDYKYQPRRRKS 181
E RL H + +P+YKY+PR +++
Sbjct: 646 EQARLSKIHLEKYPNYKYKPRPKRT 670
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 97.4 bits (241), Expect = 3e-20
Identities = 39/85 (45%), Positives = 61/85 (71%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G + ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ E
Sbjct: 589 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 648
Query: 157 EAERLRVQHKKDHPDYKYQPRRRKS 181
E RL H + +P+YKY+PR +++
Sbjct: 649 EQARLSKIHLEKYPNYKYKPRPKRT 673
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 97.4 bits (241), Expect = 3e-20
Identities = 39/85 (45%), Positives = 61/85 (71%)
Query: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
G + ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ E
Sbjct: 593 GRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYE 652
Query: 157 EAERLRVQHKKDHPDYKYQPRRRKS 181
E RL H + +P+YKY+PR +++
Sbjct: 653 EQARLSKIHLEKYPNYKYKPRPKRT 677
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 95.9 bits (237), Expect = 8e-20
Identities = 40/84 (47%), Positives = 62/84 (73%)
Query: 96 NGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFV 155
N + VKRPMNAF+VW++ RRK+A + P + N+E+SK LG W++L E+EK PF
Sbjct: 51 NSKGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFF 110
Query: 156 EEAERLRVQHKKDHPDYKYQPRRR 179
+EA++L+ H++ +P+YKY+PRR+
Sbjct: 111 QEAQKLQAMHREKYPNYKYRPRRK 134
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 86.3 bits (212), Expect = 6e-17
Identities = 44/106 (41%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 98 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEE 157
S HVKRPMNAFMVWA+ R LA P +NAE+S LG W L+E +K+P+ +E
Sbjct: 330 SKDRNGHVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDE 389
Query: 158 AERLRVQHKKDHPDYKYQPR--RRKSVKNGQAEAEEATEQTHISPN 201
A++++ +H+++ P + YQPR +RK + T Q IS N
Sbjct: 390 AQKIKEKHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTN 435
Score = 31.2 bits (69), Expect = 2.3
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 339 QQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIK 398
++A P PP QP PAP PP P AA P + TL+ +S S
Sbjct: 2 ERARPEPPPQPRPLRPAP--PPLPVEGTSFWAAAMEPPPSSPTLSAAASATLASSCGEAV 59
Query: 399 TEQLSPSHYSEQQQHSPQQIAYSP 422
L P+ Q P+Q+ P
Sbjct: 60 ASGLQPA-VRRLLQVKPEQVLLLP 82
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 76.3 bits (186), Expect = 6e-14
Identities = 109/462 (23%), Positives = 162/462 (35%), Gaps = 97/462 (20%)
Query: 22 PSPTMSEDSA-GSPCPSG---SGSDTENTRPQENTFPKGEPDLKKESE---EDKFPVCIR 74
P T E G P P G SG T +E + P GEP L E+E +D F +
Sbjct: 98 PGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMS 157
Query: 75 EAVSQVL---KGYDWTLVPMPVRVNGSS---------KNKPHVKRPMNAFMVWAQAARRK 122
+ L K +L +P + SS + K H++RPMNAFM++++ R
Sbjct: 158 PEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRAL 217
Query: 123 LADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSV 182
+ ++P+ N +SK LG+ W L EK+ + + A +++ H K HPD+K+ + RK
Sbjct: 218 VHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKS 277
Query: 183 KN-------GQAEAEEATEQTHISPNAIFKA---------------LQAD--SPHSSS-G 217
+ G A + T + +S A L +D +P SSS G
Sbjct: 278 SSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCG 337
Query: 218 MSEVHSPG----------EHSG------------------QSQGPPTPPTTPKTDVQ--- 246
+H+ G HSG Q P + PK Q
Sbjct: 338 AERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGA 397
Query: 247 PGKADLKREGRPLPEGGRQPPI------------------DFRDVDIGELSSDVISNIET 288
PG EG L GR P + + R V E D + +
Sbjct: 398 PGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDG 457
Query: 289 FDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQ 348
F + D G+ G +P + S PP +
Sbjct: 458 FGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPV----IRSSFTHCRPPLDPE 513
Query: 349 PPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPG 390
PP P P A + + P A+ P A T+ S G
Sbjct: 514 PPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555
Score = 36.2 bits (82), Expect = 0.073
Identities = 39/163 (23%), Positives = 57/163 (34%), Gaps = 25/163 (15%)
Query: 231 SQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPID-FRDVDIGELSSDVISNIETF 289
SQ PP+ T T P A + +G P P P F G ++ +++
Sbjct: 1112 SQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVA----- 1166
Query: 290 DVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQP 349
P P A S + S A ++G + +Q P P +
Sbjct: 1167 ---------PKAQRPSPKAPQKVKAAIASIPVGSFEA--GASGRPGPAPRQPLEPGPVRE 1215
Query: 350 PQAP-------PAPQA-PPQPQAAPPQQPAAPPQQPQAHTLTT 384
P AP P P A PP P+ P ++PP P A T+
Sbjct: 1216 PTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTS 1258
Score = 30.4 bits (67), Expect = 4.0
Identities = 21/69 (30%), Positives = 25/69 (36%), Gaps = 8/69 (11%)
Query: 299 PPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQA 358
PP G PA T S +P+S + PPPP P Q P +
Sbjct: 1539 PPTGTAAAPAP------TPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQ--PGWEG 1590
Query: 359 PPQPQAAPP 367
PQP PP
Sbjct: 1591 APQPSPPPP 1599
Score = 30.0 bits (66), Expect = 5.2
Identities = 49/211 (23%), Positives = 65/211 (30%), Gaps = 20/211 (9%)
Query: 234 PPTPPTTPKTDVQPGKADLKREGRPL---PEGGRQPPIDFRDVDIGELSSDVISNIETFD 290
P +P T P QP K L R GG P+ + V S T
Sbjct: 980 PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPAS--SQAGTVTSYGPTSS 1037
Query: 291 VNEFDQYLPPNG----HPGVPATHGQVTYTGSYGISSTA------ATPASAGHVWMSKQQ 340
V L P+G P + A + G G+S A A G V +
Sbjct: 1038 VALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYS 1097
Query: 341 APPPPPQ-----QPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRT 395
P P QP QAPP+ PP P P T T + P S
Sbjct: 1098 GSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATA 1157
Query: 396 HIKTEQLSPSHYSEQQQHSPQQIAYSPFNLP 426
T L +PQ++ + ++P
Sbjct: 1158 GSMTYSLVAPKAQRPSPKAPQKVKAAIASIP 1188
Score = 30.0 bits (66), Expect = 5.2
Identities = 19/54 (35%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 340 QAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQ 393
QA P Q P P P PP AA P +P P T+ SS+ G +Q
Sbjct: 1520 QAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDP---TSPSSDSGTAQ 1570
Score = 29.6 bits (65), Expect = 6.8
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
Query: 299 PPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQ-PPQAPPAPQ 357
P PG A TG+ ++ A TP+ AG + + Q PP PP
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGT--AAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPES 1581
Query: 358 APPQPQAAPPQQPAAPPQQP 377
P QP QP+ PP P
Sbjct: 1582 GPGQPGWEGAPQPSPPPPGP 1601
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 72.8 bits (177), Expect = 7e-13
Identities = 57/234 (24%), Positives = 100/234 (42%), Gaps = 34/234 (14%)
Query: 89 VPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNE 148
V PV V + KPHVK+P+NAFM++ + R K+ + +A +++ LG+ W L+
Sbjct: 330 VKSPVTVKKEEEKKPHVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSR 389
Query: 149 SEKRPFVEEAERLRVQHKKDHPDY--------KYQPRRRKSVKNGQAEAEEATEQTHISP 200
E+ + E A + R H + +P + K + +R K + Q++ + + ++
Sbjct: 390 EEQAKYYELARKERQLHSQLYPTWSARDNYGKKKKRKREKQLSQTQSQQQVQEAEGALAS 449
Query: 201 NAIFKALQ-------ADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLK 253
+ +Q DSP SS G S + SP S P P T QP K
Sbjct: 450 KSKKPCVQYLPPEKPCDSPASSHG-SMLDSPATPSAALASPAAPAATHSEQAQPLSLTTK 508
Query: 254 REGR------------------PLPEGGRQPPIDFRDVDIGELSSDVISNIETF 289
E R + G QPP+ R + +G + + ++++ +F
Sbjct: 509 PETRAQLALHSAAFLSAKAAASSSGQMGSQPPLLSRPLPLGSMPTALLASPPSF 562
>gi|71143137 high-mobility group box 3 [Homo sapiens]
Length = 200
Score = 62.8 bits (151), Expect = 7e-10
Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 11/110 (10%)
Query: 97 GSSKNKPHV-KRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFV 155
G K P+ KRP + F ++ R K+ P + +++K LG++W LN+SEK+P++
Sbjct: 84 GKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLNDSEKQPYI 143
Query: 156 EEAERLRVQHKKDHPDYKYQPR----------RRKSVKNGQAEAEEATEQ 195
+A +L+ +++KD DYK + + RK V+ E EE E+
Sbjct: 144 TKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKVEEEDEEEEEEEEE 193
Score = 33.9 bits (76), Expect = 0.36
Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 106 KRPMNAFMVWAQAARRKLADQYPHL--HNAELSKTLGKLWRLLNESEKRPFVEEAERLRV 163
K M+A+ + Q R + + P + + AE SK + W+ ++ EK F E A+ +V
Sbjct: 10 KGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKV 69
Query: 164 QHKKDHPDY 172
++ ++ DY
Sbjct: 70 RYDREMKDY 78
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 59.7 bits (143), Expect = 6e-09
Identities = 40/100 (40%), Positives = 45/100 (45%), Gaps = 15/100 (15%)
Query: 338 KQQAPPPPPQQPPQAPPAPQAPPQPQA-----APPQQPAAPPQQPQAHTLTTLSSEPGQS 392
+QQ PPP Q PQ PAPQAP Q Q PPQQP QQP A T + Q
Sbjct: 193 QQQQPPPSTNQHPQ--PAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQ 250
Query: 393 QRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSY 432
+ H SH Q Q SP Q + SP P SP +
Sbjct: 251 HQPH--------SHSQNQNQPSPTQQSSSPPQKPSQSPGH 282
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/86 (34%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 323 STAATPASAGHVWMSKQQAP--PPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAH 380
ST P A QQ P P PPQQPP PA Q PP P + Q P QP +H
Sbjct: 200 STNQHPQPAPQAPSQSQQQPLQPTPPQQPP---PASQQPPAPTSQLQQAPQPQQHQPHSH 256
Query: 381 TLTTLSSEPGQSQRTHIKTEQLSPSH 406
+ P Q + + SP H
Sbjct: 257 SQNQNQPSPTQQSSSPPQKPSQSPGH 282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,152,731
Number of Sequences: 37866
Number of extensions: 1743080
Number of successful extensions: 48303
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1097
Number of HSP's successfully gapped in prelim test: 1295
Number of HSP's that attempted gapping in prelim test: 15044
Number of HSP's gapped (non-prelim): 16638
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.