Guide to the Human Genome
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Name: SOX2 Sequence: fasta or formatted (317aa) NCBI GI: 28195386
Description:

sex-determining region Y-box 2

Referenced in:

SOX Family
Stem Cells and Early Development

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         26           4
 C cysteine            0.3          1           1
 D aspartate           2.8          9           1
 E glutamate           3.8         12           1
 F phenylalanine       0.6          2           1
 G glycine            11.0         35           5
 H histidine           3.5         11           1
 I isoleucine          1.3          4           1
 K lysine              5.4         17           2
 L leucine             6.3         20           2
 M methionine          7.9         25           2
 N asparagine          4.7         15           1
 P proline             8.2         26           2
 Q glutamine           5.7         18           2
 R arginine            5.4         17           2
 S serine             11.4         36           3
 T threonine           4.4         14           1
 V valine              3.8         12           2
 W tryptophan          0.9          3           1
 Y tyrosine            4.4         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sex-determining region Y-box 2 
SOX1                  0.514   SRY (sex determining region Y)-box 1 
SOX3                  0.506   SRY (sex determining region Y)-box 3 
SOX21                 0.250   SRY-box 21 
SOX14                 0.242   SRY-box 14 
SOX15                 0.190   SRY-box 15 
SRY                   0.169   sex determining region Y 
SOX17                 0.166   SRY-box 17 
SOX10                 0.166   SRY (sex determining region Y)-box 10 
SOX12                 0.156   SRY (sex determining region Y)-box 12 
SOX11                 0.156   SRY-box 11 
SOX18                 0.155   SRY-box 18 
SOX8                  0.152   SRY (sex determining region Y)-box 8 
SOX9                  0.150   transcription factor SOX9 
SOX4                  0.150   SRY (sex determining region Y)-box 4 
SOX7                  0.145   SRY-box 7 
SOX5                  0.121   SRY (sex determining region Y)-box 5 isoform c [Homo...
SOX5                  0.121   SRY (sex determining region Y)-box 5 isoform b [Homo...
SOX5                  0.121   SRY (sex determining region Y)-box 5 isoform a [Homo...
SOX6                  0.120   SRY (sex determining region Y)-box 6 isoform 4 [Hom...
SOX6                  0.120   SRY (sex determining region Y)-box 6 isoform 3 [Hom...
SOX6                  0.120   SRY (sex determining region Y)-box 6 isoform 1 [Homo...
SOX6                  0.120   SRY (sex determining region Y)-box 6 isoform 2 [Homo...
SOX13                 0.116   SRY-box 13 
SOX30                 0.099   SRY (sex determining region Y)-box 30 isoform b [Homo...
SOX30                 0.099   SRY (sex determining region Y)-box 30 isoform a [Hom...
CIC                   0.094   capicua homolog 
HMGB3                 0.059   high-mobility group box 3 
LOC729595             0.054   PREDICTED: similar to high mobility group box 3 [Ho...
LOC729595             0.054   PREDICTED: similar to high mobility group box 3 [Ho...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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