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Search of human proteins with 13186314
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13186314 calpain 10 isoform g [Homo sapiens]
(139 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13186314 calpain 10 isoform g [Homo sapiens] 301 1e-82
gi|89353291 calpain 10 isoform c [Homo sapiens] 198 1e-51
gi|13186302 calpain 10 isoform a [Homo sapiens] 198 1e-51
gi|10864059 calpain 10 isoform h [Homo sapiens] 100 6e-22
gi|38707981 calpain 12 [Homo sapiens] 65 1e-11
gi|4557405 calpain 3 isoform a [Homo sapiens] 65 2e-11
gi|27765072 calpain 3 isoform b [Homo sapiens] 65 2e-11
gi|27765074 calpain 3 isoform c [Homo sapiens] 65 2e-11
gi|37577157 calpain 5 [Homo sapiens] 62 1e-10
gi|157389005 calpain 2 isoform 1 [Homo sapiens] 61 3e-10
gi|221554549 calpain 8 [Homo sapiens] 57 4e-09
gi|215490104 calpain 11 [Homo sapiens] 57 4e-09
gi|12408656 calpain 1, large subunit [Homo sapiens] 57 5e-09
gi|7705383 calpain 9 isoform 2 [Homo sapiens] 53 7e-08
gi|5729758 calpain 9 isoform 1 [Homo sapiens] 53 7e-08
gi|223468608 calpain 14 [Homo sapiens] 52 2e-07
gi|47078247 calpain 3 isoform f [Homo sapiens] 49 2e-06
gi|41152101 calpain 13 [Homo sapiens] 48 2e-06
gi|5032105 small optic lobes [Homo sapiens] 40 8e-04
gi|225703100 calpain 2 isoform 2 [Homo sapiens] 39 0.001
gi|13186316 calpain 6 [Homo sapiens] 39 0.002
gi|94680985 cyclin J-like [Homo sapiens] 28 3.1
gi|126116589 fibrocystin L [Homo sapiens] 28 3.1
gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapi... 27 7.0
gi|213512168 hypothetical protein LOC259308 [Homo sapiens] 27 7.0
>gi|13186314 calpain 10 isoform g [Homo sapiens]
Length = 139
Score = 301 bits (771), Expect = 1e-82
Identities = 139/139 (100%), Positives = 139/139 (100%)
Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP
Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQLPADWTCKVQPVWLEFPCLPISC 120
REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQLPADWTCKVQPVWLEFPCLPISC
Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQLPADWTCKVQPVWLEFPCLPISC 120
Query: 121 RLRVSSDTSPDSATWGSWK 139
RLRVSSDTSPDSATWGSWK
Sbjct: 121 RLRVSSDTSPDSATWGSWK 139
>gi|89353291 calpain 10 isoform c [Homo sapiens]
Length = 517
Score = 198 bits (503), Expect = 1e-51
Identities = 101/131 (77%), Positives = 105/131 (80%), Gaps = 15/131 (11%)
Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP
Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQ-------LPADWTCKVQPV--WL 111
REGQVKQGLLGDCWFLCACAALQKSRHLLDQV P Q +TC++ W+
Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120
Query: 112 E------FPCL 116
E PCL
Sbjct: 121 EVTTDDRLPCL 131
>gi|13186302 calpain 10 isoform a [Homo sapiens]
Length = 672
Score = 198 bits (503), Expect = 1e-51
Identities = 101/131 (77%), Positives = 105/131 (80%), Gaps = 15/131 (11%)
Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP
Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQ-------LPADWTCKVQPV--WL 111
REGQVKQGLLGDCWFLCACAALQKSRHLLDQV P Q +TC++ W+
Sbjct: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVIPPGQPSWADQEYRGSFTCRIWQFGRWV 120
Query: 112 E------FPCL 116
E PCL
Sbjct: 121 EVTTDDRLPCL 131
>gi|10864059 calpain 10 isoform h [Homo sapiens]
Length = 138
Score = 99.8 bits (247), Expect = 6e-22
Identities = 47/47 (100%), Positives = 47/47 (100%)
Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ 47
MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ
Sbjct: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQ 47
>gi|38707981 calpain 12 [Homo sapiens]
Length = 719
Score = 65.5 bits (158), Expect = 1e-11
Identities = 35/85 (41%), Positives = 45/85 (52%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LFRD FPA +L D P ++ + + W RP E CA P+ +D V QG LG+
Sbjct: 45 LFRDPYFPAGPDALGYDQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGN 104
Query: 73 CWFLCACAALQKSRHLLDQVSCPVQ 97
CWFL A A+L LL +V P Q
Sbjct: 105 CWFLAAAASLTLYPRLLRRVVPPGQ 129
>gi|4557405 calpain 3 isoform a [Homo sapiens]
Length = 821
Score = 64.7 bits (156), Expect = 2e-11
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD
Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128
Query: 73 CWFLCACAALQKSRHLLDQV 92
CWFL A A L ++HLL +V
Sbjct: 129 CWFLAAIACLTLNQHLLFRV 148
>gi|27765072 calpain 3 isoform b [Homo sapiens]
Length = 815
Score = 64.7 bits (156), Expect = 2e-11
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD
Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128
Query: 73 CWFLCACAALQKSRHLLDQV 92
CWFL A A L ++HLL +V
Sbjct: 129 CWFLAAIACLTLNQHLLFRV 148
>gi|27765074 calpain 3 isoform c [Homo sapiens]
Length = 729
Score = 64.7 bits (156), Expect = 2e-11
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
L+ D FP ++SLF P+ W+RP EIC PR D + QG LGD
Sbjct: 74 LYVDPEFPPDETSLFYSQKFPI-----QFVWKRPPEICENPRFIIDGANRTDICQGELGD 128
Query: 73 CWFLCACAALQKSRHLLDQV 92
CWFL A A L ++HLL +V
Sbjct: 129 CWFLAAIACLTLNQHLLFRV 148
>gi|37577157 calpain 5 [Homo sapiens]
Length = 640
Score = 62.4 bits (150), Expect = 1e-10
Identities = 37/90 (41%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF D FPA D SL+ TP R W+RP+ IC PRLF D + QG +G+
Sbjct: 26 LFEDPLFPATDDSLYYK-GTPGPAVR----WKRPKGICEDPRLFVDGISSHDLHQGQVGN 80
Query: 73 CWFLCACAALQKSRHLLDQVSCPVQLPADW 102
CWF+ AC++L SR L Q P +W
Sbjct: 81 CWFVAACSSL-ASRESLWQKVIPDWKEQEW 109
>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
Length = 700
Score = 61.2 bits (147), Expect = 3e-10
Identities = 32/83 (38%), Positives = 43/83 (51%)
Query: 10 ARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGL 69
A LF+D +FPA S+L P + I W+RP EICA P+ + QG
Sbjct: 42 AGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGA 101
Query: 70 LGDCWFLCACAALQKSRHLLDQV 92
LGDCW L A A+L + +L +V
Sbjct: 102 LGDCWLLAAIASLTLNEEILARV 124
>gi|221554549 calpain 8 [Homo sapiens]
Length = 703
Score = 57.4 bits (137), Expect = 4e-09
Identities = 30/80 (37%), Positives = 42/80 (52%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF+D FPA S+L P + + I W+RP E+C +P+ + QG LGD
Sbjct: 45 LFKDPEFPACPSALGYKDLGPGSPQTQGIIWKRPTELCPSPQFIVGGATRTDICQGGLGD 104
Query: 73 CWFLCACAALQKSRHLLDQV 92
CW L A A+L + LL +V
Sbjct: 105 CWLLAAIASLTLNEELLYRV 124
>gi|215490104 calpain 11 [Homo sapiens]
Length = 739
Score = 57.4 bits (137), Expect = 4e-09
Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 12 ELFRDAAFPAADSSL-FCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLL 70
ELF D FPA SSL F DL P ++ ++I+W+RP++I P D + QG+L
Sbjct: 78 ELFEDPLFPAEPSSLGFKDLG-PNSKNVQNISWQRPKDIINNPLFIMDGISPTDICQGIL 136
Query: 71 GDCWFLCACAALQKSRHLLDQV 92
GDCW L A +L LL +V
Sbjct: 137 GDCWLLAAIGSLTTCPKLLYRV 158
>gi|12408656 calpain 1, large subunit [Homo sapiens]
Length = 714
Score = 57.0 bits (136), Expect = 5e-09
Identities = 31/80 (38%), Positives = 40/80 (50%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LFRD AFP SL P + I W+RP E+ + P+ D + QG LGD
Sbjct: 55 LFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGD 114
Query: 73 CWFLCACAALQKSRHLLDQV 92
CW L A A+L + LL +V
Sbjct: 115 CWLLAAIASLTLNDTLLHRV 134
>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
Length = 664
Score = 53.1 bits (126), Expect = 7e-08
Identities = 32/80 (40%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF DA FPA++SSLF P F W+RP EI P + QG LGD
Sbjct: 42 LFEDADFPASNSSLFYS-ERPQIPF----VWKRPGEIVKNPEFILGGATRTDICQGELGD 96
Query: 73 CWFLCACAALQKSRHLLDQV 92
CW L A A+L ++ L +V
Sbjct: 97 CWLLAAIASLTLNQKALARV 116
>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
Length = 690
Score = 53.1 bits (126), Expect = 7e-08
Identities = 32/80 (40%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF DA FPA++SSLF P F W+RP EI P + QG LGD
Sbjct: 42 LFEDADFPASNSSLFYS-ERPQIPF----VWKRPGEIVKNPEFILGGATRTDICQGELGD 96
Query: 73 CWFLCACAALQKSRHLLDQV 92
CW L A A+L ++ L +V
Sbjct: 97 CWLLAAIASLTLNQKALARV 116
>gi|223468608 calpain 14 [Homo sapiens]
Length = 684
Score = 52.0 bits (123), Expect = 2e-07
Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF D +FPA SS+ + L + + W+RP E+ + P+ + + + QG++GD
Sbjct: 43 LFEDTSFPATLSSI--GSGSLLQKLPPRLQWKRPPELHSNPQFYFAKAKRLDLCQGIVGD 100
Query: 73 CWFLCACAALQKSRHLLDQV 92
CWFL A AL + +L +V
Sbjct: 101 CWFLAALQALALHQDILSRV 120
>gi|47078247 calpain 3 isoform f [Homo sapiens]
Length = 728
Score = 48.5 bits (114), Expect = 2e-06
Identities = 23/51 (45%), Positives = 29/51 (56%)
Query: 42 TWRRPQEICATPRLFPDDPREGQVKQGLLGDCWFLCACAALQKSRHLLDQV 92
T ++ EIC PR D + QG LGDCWFL A A L ++HLL +V
Sbjct: 11 TTQQKNEICENPRFIIDGANRTDICQGELGDCWFLAAIACLTLNQHLLFRV 61
>gi|41152101 calpain 13 [Homo sapiens]
Length = 669
Score = 48.1 bits (113), Expect = 2e-06
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 14 FRDAAFPAADSSLFCDLSTPLAQFR-EDITWRRPQEICATPRLFP-DDPREGQVKQGLLG 71
F+D FPAADSS+ L L + R ++ W+RPQ++ P F DD ++QG
Sbjct: 35 FKDETFPAADSSIGQKL---LQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAA 91
Query: 72 DCWFLCACAALQKS 85
DCWFL A +L ++
Sbjct: 92 DCWFLAALGSLTQN 105
>gi|5032105 small optic lobes [Homo sapiens]
Length = 1086
Score = 39.7 bits (91), Expect = 8e-04
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Query: 14 FRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP---------REGQ 64
F D +FP S+ + Q W RPQEI + +F D R
Sbjct: 488 FVDDSFPPGPESVGFPAGDSVQQRVRQ--WLRPQEINCS--VFRDHRATWSVFHTLRPSD 543
Query: 65 VKQGLLGDCWFLCACAALQKSRHLLDQVSCPVQLPADWTCKVQ 107
+ QGLLG+CWFL A A L + L+++V L A+ +V+
Sbjct: 544 ILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVR 586
>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
Length = 622
Score = 38.9 bits (89), Expect = 0.001
Identities = 18/45 (40%), Positives = 24/45 (53%)
Query: 48 EICATPRLFPDDPREGQVKQGLLGDCWFLCACAALQKSRHLLDQV 92
EICA P+ + QG LGDCW L A A+L + +L +V
Sbjct: 2 EICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARV 46
>gi|13186316 calpain 6 [Homo sapiens]
Length = 641
Score = 38.5 bits (88), Expect = 0.002
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Query: 13 LFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDPREGQVKQGLLGD 72
LF D F + SLF + P + W+RPQ+IC P L + Q+ QG LG
Sbjct: 26 LFCDPTFLPENDSLFYNRLLP-----GKVVWKRPQDICDDPHLIVGNISNHQLTQGRLGH 80
Query: 73 CWFLCA--CAALQKS 85
+ A C A+Q+S
Sbjct: 81 KPMVSAFSCLAVQES 95
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 27.7 bits (60), Expect = 3.1
Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 19/101 (18%)
Query: 1 MRAGRGATPARELFRDAAFPAADSSLFCDLSTPLAQFREDITWRRPQEICATPRLFPDDP 60
M G TP + LF+ A+PA +T LAQF+ + Q++C R
Sbjct: 315 MVPGTPPTPTQVLFQPPAYPALGQP-----ATTLAQFQTPV-----QDLCLAYRDSLQAH 364
Query: 61 REGQVKQGLLGDCWFLCACAALQKSRHLLDQVS-CPVQLPA 100
R G + G G ++L L + CPV +PA
Sbjct: 365 RSGSLLSGSTG--------SSLHTPYQPLQPLDMCPVPVPA 397
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 27.7 bits (60), Expect = 3.1
Identities = 11/34 (32%), Positives = 15/34 (44%)
Query: 101 DWTCKVQPVWLEFPCLPISCRLRVSSDTSPDSAT 134
D TCK P W + C + + V PD+ T
Sbjct: 3747 DSTCKYLPEWQSYQCFGMEYAMMVIESLDPDTET 3780
>gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo
sapiens]
Length = 256
Score = 26.6 bits (57), Expect = 7.0
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 7/40 (17%)
Query: 9 PARELFRDAAFPAADSSLFCDLS-TPLAQFREDITWRRPQ 47
PA+E+ + A+D SL DL TPL++ +E I W+RP+
Sbjct: 3 PAKEVTK-----ASDGSLLGDLGHTPLSK-KEGIKWQRPR 36
>gi|213512168 hypothetical protein LOC259308 [Homo sapiens]
Length = 1335
Score = 26.6 bits (57), Expect = 7.0
Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 89 LDQVSCPVQLPADWTCKVQPVWL--EFPCLPISCRLRVSSDTSPD 131
+ Q P + W C++ V FPC+P S L + + + PD
Sbjct: 687 IHQGKIPACVHRSWDCRISGVLAVAPFPCIPESQFLELQTASDPD 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.478
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,404,111
Number of Sequences: 37866
Number of extensions: 290621
Number of successful extensions: 670
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 640
Number of HSP's gapped (non-prelim): 25
length of query: 139
length of database: 18,247,518
effective HSP length: 92
effective length of query: 47
effective length of database: 14,763,846
effective search space: 693900762
effective search space used: 693900762
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.