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Search of human proteins with 4505505
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
(345 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 699 0.0
gi|59939900 opioid binding protein/cell adhesion molecule-like i... 645 0.0
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 547 e-156
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 539 e-153
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 519 e-147
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 491 e-139
gi|45594240 limbic system-associated membrane protein [Homo sapi... 368 e-102
gi|66346706 neuronal growth regulator 1 [Homo sapiens] 320 2e-87
gi|157819143 IgLON family member 5 [Homo sapiens] 313 2e-85
gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens] 108 9e-24
gi|109150416 peroxidasin [Homo sapiens] 100 2e-21
gi|118572606 hemicentin 1 [Homo sapiens] 100 3e-21
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 98 9e-21
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 98 9e-21
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 98 9e-21
gi|110349719 titin isoform N2-A [Homo sapiens] 97 2e-20
gi|126517478 peroxidasin homolog-like [Homo sapiens] 96 5e-20
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 96 6e-20
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 93 4e-19
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 93 4e-19
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 92 5e-19
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 92 5e-19
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 92 7e-19
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 92 9e-19
gi|205277425 immunoglobulin superfamily, member 9 isoform a [Hom... 87 2e-17
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 87 2e-17
gi|205277423 immunoglobulin superfamily, member 9 isoform b [Hom... 87 3e-17
gi|7657359 contactin 5 isoform long [Homo sapiens] 86 5e-17
gi|28373129 contactin 5 isoform short [Homo sapiens] 86 5e-17
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 85 8e-17
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 699 bits (1805), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID
Sbjct: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
Query: 61 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 120
DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD
Sbjct: 61 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 120
Query: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 180
NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF
Sbjct: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 180
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 240
VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG
Sbjct: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 240
Query: 241 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 300
ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN
Sbjct: 241 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 300
Query: 301 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF
Sbjct: 301 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
>gi|59939900 opioid binding protein/cell adhesion molecule-like
isoform b preproprotein [Homo sapiens]
Length = 338
Score = 645 bits (1665), Expect = 0.0
Identities = 322/331 (97%), Positives = 322/331 (97%)
Query: 15 VVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 74
VV S L GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI
Sbjct: 8 VVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTI 67
Query: 75 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV
Sbjct: 68 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 127
Query: 135 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 194
PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR
Sbjct: 128 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR 187
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 254
DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF
Sbjct: 188 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF 247
Query: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP 314
QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP
Sbjct: 248 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGP 307
Query: 315 GAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
GAVIDGVNSASRALACLWLSGTLLAHFFIKF
Sbjct: 308 GAVIDGVNSASRALACLWLSGTLLAHFFIKF 338
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 547 bits (1410), Expect = e-156
Identities = 264/345 (76%), Positives = 298/345 (86%), Gaps = 1/345 (0%)
Query: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID
Sbjct: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
Query: 61 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 120
+RVTRVAWLNRSTILYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTD
Sbjct: 61 NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 120
Query: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 180
NHPKTSRVHLIVQV P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GF
Sbjct: 121 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGF 179
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 240
VSEDEYLEI I R+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG
Sbjct: 180 VSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG 239
Query: 241 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 300
L CEASAVP AEFQW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+N
Sbjct: 240 TLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASN 299
Query: 301 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
KLG+TNASI L+GPGAV + N SR C+WL L+ H +KF
Sbjct: 300 KLGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 344
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 539 bits (1388), Expect = e-153
Identities = 264/356 (74%), Positives = 298/356 (83%), Gaps = 12/356 (3%)
Query: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID
Sbjct: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
Query: 61 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 120
+RVTRVAWLNRSTILYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTD
Sbjct: 61 NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 120
Query: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 180
NHPKTSRVHLIVQV P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GF
Sbjct: 121 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGF 179
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 240
VSEDEYLEI I R+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG
Sbjct: 180 VSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG 239
Query: 241 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 300
L CEASAVP AEFQW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+N
Sbjct: 240 TLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASN 299
Query: 301 KLGNTNASITLY-----------GPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 345
KLG+TNASI L+ GPGAV + N SR C+WL L+ H +KF
Sbjct: 300 KLGHTNASIMLFEVKTTALTPWKGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 355
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 519 bits (1336), Expect = e-147
Identities = 250/313 (79%), Positives = 280/313 (89%), Gaps = 1/313 (0%)
Query: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID
Sbjct: 1 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 60
Query: 61 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 120
+RVTRVAWLNRSTILYAGNDKW +DPRV++L NT TQYSI IQNVDVYDEGPYTCSVQTD
Sbjct: 61 NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 120
Query: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 180
NHPKTSRVHLIVQV P+I+ ISSDI++NEG++++L C+A GRPEPTVTWRH+S K GF
Sbjct: 121 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGF 179
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 240
VSEDEYLEI I R+QSG+YECSA NDVAAP VR+VK+TVNYPPYIS+AK TGV VGQKG
Sbjct: 180 VSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG 239
Query: 241 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 300
L CEASAVP AEFQW+K++ RL G G+++EN+ +S L FFNVSE DYGNYTCVA+N
Sbjct: 240 TLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASN 299
Query: 301 KLGNTNASITLYG 313
KLG+TNASI L+G
Sbjct: 300 KLGHTNASIMLFG 312
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 491 bits (1264), Expect = e-139
Identities = 237/318 (74%), Positives = 271/318 (85%), Gaps = 1/318 (0%)
Query: 28 GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPR 87
GVPVRSGDATFPKAMDNVTVRQGESATLRCTID+RVTRVAWLNRSTILYAGNDKW +DPR
Sbjct: 28 GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTILYAGNDKWCLDPR 87
Query: 88 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV 147
V++L NT TQYSI IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV P+I+ ISSDI++
Sbjct: 88 VVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISI 147
Query: 148 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALND 207
NEG++++L C+A GRPEPTVTWRH+S K GFVSEDEYLEI I R+QSG+YECSA ND
Sbjct: 148 NEGNNISLTCIATGRPEPTVTWRHISPK-AVGFVSEDEYLEIQGITREQSGDYECSASND 206
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
VAAP VR+VK+TVNYPPYIS+AK TGV VGQKG L CEASAVP AEFQW+K++ RL G
Sbjct: 207 VAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGK 266
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNSASRA 327
G+++EN+ +S L FFNVSE DYGNYTCVA+NKLG+TNASI L+GPGAV + N SR
Sbjct: 267 KGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVSNGTSRR 326
Query: 328 LACLWLSGTLLAHFFIKF 345
C+WL L+ H +KF
Sbjct: 327 AGCVWLLPLLVLHLLLKF 344
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 368 bits (944), Expect = e-102
Identities = 181/322 (56%), Positives = 247/322 (76%), Gaps = 5/322 (1%)
Query: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNR 71
K L +V LRLL L+PTG+PVRS D F + DN+TVRQG++A LRC ++D+ ++VAWLNR
Sbjct: 10 KQLPLVLLRLLCLLPTGLPVRSVD--FNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNR 67
Query: 72 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
S I++AG+DKWS+DPRV + +YS+ IQ VDVYDEG YTCSVQT + PKTS+V+LI
Sbjct: 68 SGIIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLI 127
Query: 132 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 191
VQVPP+I NISSD+TVNEGS+VTL+C+A GRPEP +TWRHL+ G+ F E+EYLEI
Sbjct: 128 VQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLT-PTGREFEGEEEYLEILG 186
Query: 192 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM 251
I R+QSG+YEC A N+V++ DV++VK+TVNYPP I+++K+ + G++ L CEASAVP
Sbjct: 187 ITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPA 246
Query: 252 AEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+F+W++++TR+ + +G+ I++ S+LT NV+E+ YGNYTCVA NKLG TNAS+ L
Sbjct: 247 PDFEWYRDDTRINSA-NGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVL 305
Query: 312 YGPGAVIDGVNSASRALACLWL 333
+ PG+V G+N + LWL
Sbjct: 306 FRPGSV-RGINGSISLAVPLWL 326
>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
Length = 354
Score = 320 bits (819), Expect = 2e-87
Identities = 161/329 (48%), Positives = 220/329 (66%), Gaps = 4/329 (1%)
Query: 14 LVVVSLRLLFLVPTGVPVRSGDATFP-KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS 72
L V L L L+P+ +P FP A+DN+ VR+G++A LRC ++D ++ AWLNRS
Sbjct: 17 LAAVLLSLCCLLPSCLPAGQS-VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRS 75
Query: 73 TILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV 132
+I++AG DKWS+DPRV I YS+ IQNVDV D+GPYTCSVQT + P+T +VHL V
Sbjct: 76 SIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTV 135
Query: 133 QVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDI 192
QVPP+I +IS+D+TVNEG++VTL CLA G+PEP+++WRH+S +YL+I I
Sbjct: 136 QVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKP--FENGQYLDIYGI 193
Query: 193 KRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMA 252
RDQ+GEYECSA NDV+ PDVRKVK+ VN+ P I + K+ V+ G+ G++ CE + VP
Sbjct: 194 TRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPP 253
Query: 253 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
F+W+K E +L G G+ I+N S LT NV+++ +GNYTCVA NKLG TNAS+ L
Sbjct: 254 AFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
Query: 313 GPGAVIDGVNSASRALACLWLSGTLLAHF 341
P G+ ++ L W L+ F
Sbjct: 314 PPSTAQYGITGSADVLFSCWYLVLTLSSF 342
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 313 bits (801), Expect = 2e-85
Identities = 167/328 (50%), Positives = 225/328 (68%), Gaps = 11/328 (3%)
Query: 12 KCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNR 71
+ L +L L ++ G+ +S + P DN TV +G++ATL C ID+ VTRVAWLNR
Sbjct: 11 RLLAAAALAGLAVISRGLLSQSLEFNSPA--DNYTVCEGDNATLSCFIDEHVTRVAWLNR 68
Query: 72 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 131
S ILYAGND+W+ DPRV +L+NTP ++SI+I V + DEG YTCS QT + P T++V+LI
Sbjct: 69 SNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYTTQVYLI 128
Query: 132 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 191
V VP +I+NISS +TVNEG +V LLCLA+GRPEPTVTWR L GF SE E LEISD
Sbjct: 129 VHVPARIVNISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQLR----DGFTSEGEILEISD 184
Query: 192 IKRDQSGEYECSALNDV-AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVP 250
I+R Q+GEYEC N V +APD R+V +TVNYPP I+ + ++G+ +L CEA AVP
Sbjct: 185 IQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVP 244
Query: 251 MAEFQWFKEETRLATGL-DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
A+FQW+K++ L++G +G++++ + S L F NVS + YGNYTC A N+LG ++AS+
Sbjct: 245 PADFQWYKDDRLLSSGTAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASM 304
Query: 310 TLYGPGAVIDGVNSASRALACLWLSGTL 337
L PG++ NSA R L L L
Sbjct: 305 RLLRPGSL---ENSAPRPPGLLALLSAL 329
>gi|148886752 immunoglobulin superfamily, member 9B [Homo sapiens]
Length = 1349
Score = 108 bits (269), Expect = 9e-24
Identities = 90/305 (29%), Positives = 133/305 (43%), Gaps = 38/305 (12%)
Query: 45 VTVRQGESATLRCTIDDRVTR------VAWLNRST----ILYAGNDKWSIDPRVIILVNT 94
VT R GES LRC + VT V W + G +DP +
Sbjct: 33 VTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASL 92
Query: 95 PTQYSIMIQNVDVYDEGPYTCSV-----QTDNHPKTSRVHLIVQVPPQIMNISSD-ITVN 148
+ S+ ++ V D+G Y C V Q D S VHL + PP I
Sbjct: 93 HDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAK 152
Query: 149 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 202
EG S+T+ C A G P+P VTW +KEG + +Y L ++ + R+ G Y C
Sbjct: 153 EGGSITMTCTAFGNPKPIVTW----LKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTC 208
Query: 203 SALNDVAAPDVRKVKITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVP-MAEFQWFKEE 260
A + + V + V PP+I S +N V++ Q +L+C A A P + W+ ++
Sbjct: 209 RAYS-IQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQD 267
Query: 261 TRLATGLD---GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG---NTNASITLYGP 314
+ D +RI G TL F V +D G YTCV +N LG + +A +T+ P
Sbjct: 268 ENVYFQNDLKLRVRILIDG---TLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYP 324
Query: 315 GAVID 319
V++
Sbjct: 325 ARVLN 329
Score = 74.7 bits (182), Expect = 1e-13
Identities = 75/278 (26%), Positives = 110/278 (39%), Gaps = 31/278 (11%)
Query: 45 VTVRQGESATLRCT-IDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
+ ++G S T+ CT + V WL T+L A K+ + + S+ +
Sbjct: 149 IEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASG-KYQV-----------SDGSLTVT 196
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 163
+V D G YTC + HL+VQ PP I++ +ITVN L C A P
Sbjct: 197 SVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYP 256
Query: 164 -EPTVTWRHLSVKEGQGFVSE---------DEYLEISDIKRDQSGEYECSALNDVAAPDV 213
T TW E F ++ D L I +K + SG+Y C N +
Sbjct: 257 GNLTYTWYWQD--ENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPS 314
Query: 214 RKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAE-FQWFKEETRLATGLD-GM 270
+TV YP ++ V VG G + C A P A +W K+ L + G
Sbjct: 315 ASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGW 374
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 308
+ G ++ +E+ G YTCV N LG S
Sbjct: 375 TLMEDG---SIRIEEATEEALGTYTCVPYNTLGTMGQS 409
Score = 66.2 bits (160), Expect = 4e-11
Identities = 74/295 (25%), Positives = 121/295 (41%), Gaps = 34/295 (11%)
Query: 43 DNVTVRQGESATLRCTIDDRVTRVA--WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSI 100
+N+TV + A L C + + W + +Y ND + RV IL++ ++
Sbjct: 236 ENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQND---LKLRVRILIDG----TL 288
Query: 101 MIQNVDVYDEGPYTC--SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
+I V D G YTC S P S +L VQ P +++N+ I V G + C
Sbjct: 289 IIFRVKPEDSGKYTCVPSNSLGRSPSAS-AYLTVQYPARVLNMPPVIYVPVGIHGYIRCP 347
Query: 159 AIGRPEPTVT-W----RHLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAP- 211
P TV W R L V++ G+ + ED + I + + G Y C N +
Sbjct: 348 VDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMG 407
Query: 212 DVRKVKITVNYPPYISKAKNTGV--SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
++ + PPY + G++ ++ C A+ P W K G
Sbjct: 408 QSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRK------VGKPS 461
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-------YGPGAV 317
+ +L F +S++D+G + CVATN + + AS L + PG+V
Sbjct: 462 RSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSV 516
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 100 bits (249), Expect = 2e-21
Identities = 90/297 (30%), Positives = 121/297 (40%), Gaps = 37/297 (12%)
Query: 28 GVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDP 86
G P R TF N V GES TL C+ R++W +DP
Sbjct: 337 GSPARP---TFVIQPQNTEVLVGESVTLECSATGHPPPRISWTR------GDRTPLPVDP 387
Query: 87 RVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDIT 146
RV I TP+ + IQNV D G Y CS + + +IVQ PQ D
Sbjct: 388 RVNI---TPSG-GLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRV 443
Query: 147 VNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYEC 202
V EG +V C A G P P + W LSV + + V L IS + G+YEC
Sbjct: 444 VIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSV-DRRHLVLSSGTLRISGVALHDQGQYEC 502
Query: 203 SALNDVAAPDVRKVKITVN---YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 259
A+N + + V +TV P + S +T V VG L C + P W K
Sbjct: 503 QAVNIIGSQKV-VAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNK- 560
Query: 260 ETRLATGLDGMRIENKGRM-----STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
DG+++ G+ LT +V D G Y CVA N +G+ + S+ L
Sbjct: 561 --------DGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVL 609
Score = 69.7 bits (169), Expect = 4e-12
Identities = 51/184 (27%), Positives = 84/184 (45%), Gaps = 16/184 (8%)
Query: 136 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVK-EGQGFVSEDEYLEIS 190
P+I + D V G++V C A G P+P + W LS+K + + + +D L I
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQ 305
Query: 191 DIKRDQSGEYECSALNDVAAPDVRKVKITVNY------PPYISKAKNTGVSVGQKGILSC 244
+ + G Y+C A N A +V+ ++T+ Y P ++ + +NT V VG+ L C
Sbjct: 306 NTQETDQGIYQCMAKN--VAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 363
Query: 245 EASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
A+ P W + + + I G L NV + D G Y C ATN + +
Sbjct: 364 SATGHPPPRISWTRGDRTPLPVDPRVNITPSG---GLYIQNVVQGDSGEYACSATNNIDS 420
Query: 305 TNAS 308
+A+
Sbjct: 421 VHAT 424
Score = 68.9 bits (167), Expect = 6e-12
Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 12/214 (5%)
Query: 99 SIMIQNVDVYDEGPYTCSVQ-TDNHPKTSRVHLIV---QVPPQIMNISSDITVNEGSSVT 154
++MIQN D+G Y C + KT V L P + + V G SVT
Sbjct: 301 TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVT 360
Query: 155 LLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA 210
L C A G P P ++W R + + ++ L I ++ + SGEY CSA N++ +
Sbjct: 361 LECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 420
Query: 211 PDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGM 270
I P + ++ V GQ CEA P W K ++L+ +
Sbjct: 421 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHL 480
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
+ + TL V+ D G Y C A N +G+
Sbjct: 481 VLSS----GTLRISGVALHDQGQYECQAVNIIGS 510
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 99.8 bits (247), Expect = 3e-21
Identities = 82/278 (29%), Positives = 121/278 (43%), Gaps = 24/278 (8%)
Query: 44 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
++ + +S L C + T R+ W +L + ++SI L N + I
Sbjct: 3721 SLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI------LENG----FLHI 3770
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
Q+ V D G Y C R+ L V VPP I +++TV TL C A G
Sbjct: 3771 QSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGI 3830
Query: 163 PEPTVTWRH----LSVKEGQG---FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
P+P++ WR L+V + Q +S + IS D + YEC+ N A D R
Sbjct: 3831 PKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP-SVDDTATYECTVTNG-AGDDKRT 3888
Query: 216 VKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
V +TV PP I+ + + V+ +++C AS VP W K RL DG RI +
Sbjct: 3889 VDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILS 3948
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
G + L G YTCVA N G+ + +TL+
Sbjct: 3949 SGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTLH 3983
Score = 95.1 bits (235), Expect = 8e-20
Identities = 78/277 (28%), Positives = 122/277 (44%), Gaps = 27/277 (9%)
Query: 40 KAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 98
++ +N++V + S +L C + + W D W + + + + +
Sbjct: 2391 RSPENISVVEKNSVSLTCEASGIPLPSITWFK---------DGWPVSLSNSVRILSGGRM 2441
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLL 156
++Q + D G YTC V+ + L V VPP I+ N D+ V E SVTL
Sbjct: 2442 LRLMQTT-MEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLT 2500
Query: 157 CLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
C G P P +TW + L E +S +L+I++++ +G Y C A + A
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLA-SSPAGHK 2559
Query: 213 VRKVKITVNYPPYISKAKNTG------VSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
R + V P I+ + G V + L CEA + P A WFK+ T L +
Sbjct: 2560 SRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN 2619
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ +RI GR TL N E + G Y+CVATN+ G
Sbjct: 2620 RN-IRILPGGR--TLQILNAQEDNAGRYSCVATNEAG 2653
Score = 93.6 bits (231), Expect = 2e-19
Identities = 71/281 (25%), Positives = 114/281 (40%), Gaps = 32/281 (11%)
Query: 43 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIIL-----VNTPTQ 97
+NVTV GE A L C I V N W + R + L + T
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDY-------------NLTWQRNDRDVRLAEPARIRTLAN 573
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 157
S+ +++V D G Y C V ++ + V L VQ PP++ + + + GS V+++C
Sbjct: 574 LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMC 633
Query: 158 LAIGRPEPTVTWR---HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR 214
A G P+P + W V + ++ D L I + +G Y C A N
Sbjct: 634 SATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 215 KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG----LDGM 270
+ P + V++G ++ C+ S +P + +WFK + L +D +
Sbjct: 694 STLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPL 753
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ L + D G+YTCVA N+ G ITL
Sbjct: 754 -------LGLLKIQETQDLDAGDYTCVAINEAGRATGKITL 787
Score = 92.8 bits (229), Expect = 4e-19
Identities = 84/297 (28%), Positives = 120/297 (40%), Gaps = 25/297 (8%)
Query: 23 FLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDK 81
+LV VP P+ ++TV + TL C D V WL L A
Sbjct: 3612 YLVRVHVPPNIAGTDEPR---DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQA---- 3664
Query: 82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 141
PRV IL + +Y + I N D+ D YTC T L V VPP I
Sbjct: 3665 ---TPRVRIL--SGGRY-LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGG 3718
Query: 142 SSDITVNEGSSVTLLCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQS 197
+ + S L C+A G P P +TWR L+ + + E+ +L I +
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDT 3778
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQW 256
G Y C A N A D R++ + V+ PP I+ N V V + L+CEA+ +P W
Sbjct: 3779 GRYLCMATN-AAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINW 3837
Query: 257 FKEETRLAT--GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
K L + R+ + G +L + S D Y C TN G+ ++ L
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSG---SLVIISPSVDDTATYECTVTNGAGDDKRTVDL 3891
Score = 91.3 bits (225), Expect = 1e-18
Identities = 78/277 (28%), Positives = 118/277 (42%), Gaps = 24/277 (8%)
Query: 46 TVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 104
TV + A L C D T + W + +L K++ +P ++++N
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEP----------YGELILEN 4228
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 164
V + D G YTC T V L V V P + D+++N+G + L C A G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 165 PTVTWRHLSVKEGQGFVSEDEYLE--ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
P +TW + F S + + E I + ++ SG Y C+A N V V+ +
Sbjct: 4289 PKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGF--VKAIGFVYVK 4346
Query: 223 PPYISKA---KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMS 279
P + K N +G IL+CE P QW ++ + RI G S
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS---HRIRQLGNGS 4403
Query: 280 TLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGP 314
+ V+E D G+YTCVATN+ G + S+TL P
Sbjct: 4404 LAIYGTVNE-DAGDYTCVATNEAGVVERSMSLTLQSP 4439
Score = 90.9 bits (224), Expect = 2e-18
Identities = 62/210 (29%), Positives = 95/210 (45%), Gaps = 10/210 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDI--TVNEGSSVTLLCLAIGRPEPT 166
D G YTC + L V PP + + + TV + V L C A G P P
Sbjct: 1892 DAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPV 1951
Query: 167 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
+TW R LS F++ + ++I + +G Y+C A+N A ++ + V+
Sbjct: 1952 ITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELF-YSLQVHV 2010
Query: 223 PPYISKAKN-TGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTL 281
P IS + N V V L CEA +P W K+ + +++ +G+++ + GR+ L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILAL 2070
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
T +S D G YTCVA N G I L
Sbjct: 2071 TSAQIS--DTGRYTCVAVNAAGEKQRDIDL 2098
Score = 90.9 bits (224), Expect = 2e-18
Identities = 77/283 (27%), Positives = 118/283 (41%), Gaps = 23/283 (8%)
Query: 40 KAMDNVTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 98
+++ V VR+G S +L C + V W ++ V IL + +
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITEST-------HVEILADGQMLH 3116
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSS-VTLLC 157
I+ +V D G Y C HL V VPP I ++ V S+ VTL C
Sbjct: 3117 ---IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC 3173
Query: 158 LAIGRPEPTVTW--RHLSVKEGQGF----VSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
A G P PT+ W H ++ +S L+I+ + SG Y C A N +
Sbjct: 3174 DATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN-MEGK 3232
Query: 212 DVRKVKITVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
+ +++ PP ++ A+ + V +G+ L C A+ +P QW K+ +A+G +
Sbjct: 3233 AQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASG-E 3291
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
RI STL + D G YTCVATN G + L
Sbjct: 3292 TERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNL 3334
Score = 89.4 bits (220), Expect = 4e-18
Identities = 66/211 (31%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G Y C Q ++ L VQVPP I + + +TL C A G P P +T
Sbjct: 4052 DAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDIT 4111
Query: 169 WRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 221
W K+G+ V L+I+ ++ +G Y C A N VA K+TV+
Sbjct: 4112 WH----KDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAAN-VAGSSSTSTKLTVH 4166
Query: 222 YPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMST 280
PP I S + V+ + IL C A +P W K+ LA L E G
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGE--- 4223
Query: 281 LTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L NV +D G YTCVA N G +++L
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Score = 89.4 bits (220), Expect = 4e-18
Identities = 67/234 (28%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 82 WSIDPRVI---ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI 138
W D R I I + S+ I V D G YTC ++ L V VPP+I
Sbjct: 4112 WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRI 4171
Query: 139 MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--GFVSEDEY--LEISDIKR 194
+ TVNE S L C+A G P P + W+ +V G + + Y L + ++
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVL 4231
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVN-YPPYISKAKNTGVSVGQKGILSCEASAVPMAE 253
+ SG Y C A N+ A D V +TV+ P + + ++ G++ LSC+A+ +P+ +
Sbjct: 4232 EDSGFYTCVA-NNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPK 4290
Query: 254 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
W + D + S L VS++D G Y C A N +G A
Sbjct: 4291 LTWTFNNNIIPAHFDSV-----NGHSELVIERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 88.2 bits (217), Expect = 1e-17
Identities = 60/219 (27%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD----ITVNEG 150
P ++ I V D G YTC + L V VPP I + S+ + V EG
Sbjct: 3015 PGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREG 3074
Query: 151 SSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 206
+SV+L C + P P +TW R ++ +++ + L I + +G+Y C A+N
Sbjct: 3075 TSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAIN 3134
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNTGV--SVGQKGILSCEASAVPMAEFQWFKEETRLA 264
VA D + + V PP I + + ++ L+C+A+ +P W K R+
Sbjct: 3135 -VAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIE 3193
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
D + + S L D GNYTC+A+N G
Sbjct: 3194 NS-DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 87.4 bits (215), Expect = 2e-17
Identities = 67/215 (31%), Positives = 101/215 (46%), Gaps = 15/215 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS---DITVNEGSSVTLL 156
+ I + D Y+C +L V + P I N S +I V G S++L
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLE 2313
Query: 157 CLAIGRPEPTVTWR---HLSVK-EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
C G P PTVTW H +K +G + E L++ +I +G Y C A+N VA
Sbjct: 2314 CEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVN-VAGMT 2372
Query: 213 VRKVKITVNYPPYI--SKAKNTGVSVGQKG--ILSCEASAVPMAEFQWFKEETRLATGLD 268
+K ++V+ PP I + +SV +K L+CEAS +P+ WFK+ ++ +
Sbjct: 2373 DKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-N 2431
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+RI + GRM L + +D G YTCV N G
Sbjct: 2432 SVRILSGGRM--LRLMQTTMEDAGQYTCVVRNAAG 2464
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/280 (26%), Positives = 113/280 (40%), Gaps = 30/280 (10%)
Query: 47 VRQGESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 104
V +G+ TL CT+ + + W+ S +L + + S+ I+
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-----------YITVRSDGSLHIER 949
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 164
V + D G YTC ++V V P I + ++ EG VTL C A G P+
Sbjct: 950 VQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPK 1009
Query: 165 PTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
P+V W +S + D L + ++SGEY C+A N A RKV++TV
Sbjct: 1010 PSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN-TAGYAKRKVQLTV 1068
Query: 221 NYPPYI-------SKAKNTGVSV--GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
P + S+ K +SV G++ L CE ++P W KE ++
Sbjct: 1069 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHT 1128
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G M D G Y CVATN GN ++ L
Sbjct: 1129 FLPSGSMK---ITETRTSDSGMYLCVATNIAGNVTQAVKL 1165
Score = 87.0 bits (214), Expect = 2e-17
Identities = 79/285 (27%), Positives = 114/285 (40%), Gaps = 41/285 (14%)
Query: 42 MDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSI 100
+++V V++ +S TL C + V + W L I +
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFL---------- 2535
Query: 101 MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----ITVNEGSSVTL 155
I NV V G YTC + K+ L V V P I + SD +TV S +L
Sbjct: 2536 QITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSL 2595
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKRDQSGEYECSALND 207
+C A P T+TW K+G S L+I + + D +G Y C A N+
Sbjct: 2596 VCEAYSYPPATITW----FKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI---------LSCEASAVPMAEFQWFK 258
A ++ ++ V PP I+K G + K + L CEA A+P A W+K
Sbjct: 2652 -AGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 259 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ L + D + I G TL D G YTCVA+N G
Sbjct: 2711 DGQPLKSD-DHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAG 2752
Score = 85.1 bits (209), Expect = 8e-17
Identities = 71/249 (28%), Positives = 110/249 (44%), Gaps = 27/249 (10%)
Query: 87 RVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-- 144
+V+IL P + I V D G YTC + + + + V VPP I +SD
Sbjct: 2823 KVLIL---PGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLP 2879
Query: 145 --ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKR 194
+TV S + CL+ G P P +W+ K+GQ + +D + L+I + +
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQ----KDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYI--SKAKNTGVSVGQKGILSCEASAVPMA 252
G Y C A N A + + V+ PP + K++N V V L+CE S P
Sbjct: 2936 TDIGRYVCVAEN-TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPP 2994
Query: 253 EFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SIT 310
+ W K E + + + + GR TL D G YTC+A N+ G + S+T
Sbjct: 2995 DLSWLKNEQPIKLNTNTLIVPG-GR--TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLT 3051
Query: 311 LYGPGAVID 319
+Y P ++ D
Sbjct: 3052 VYVPPSIKD 3060
Score = 82.0 bits (201), Expect = 7e-16
Identities = 62/220 (28%), Positives = 97/220 (44%), Gaps = 11/220 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ + + + D G YTC K + L V VPP IM +++V +V LLC +
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQS 2127
Query: 160 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
P PT+TW L K G L+I D + +G Y C A N VA +
Sbjct: 2128 DAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATN-VAGKTEKN 2186
Query: 216 VKITVNYPPYISKAKN-TGVSVGQKGILS--CEASAVPMAEFQWFKEETRLATGLDG-MR 271
+ + PP I + T ++V + ++S CE+S +P W K+ + + T G +R
Sbjct: 2187 YNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVR 2246
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
I + GR ++ + D Y+CVA+N G L
Sbjct: 2247 ILSGGRQLQISI--AEKSDAALYSCVASNVAGTAKKEYNL 2284
Score = 81.6 bits (200), Expect = 9e-16
Identities = 62/206 (30%), Positives = 94/206 (45%), Gaps = 10/206 (4%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 170
G YTC + V L V PP I S++ V + + L C A G P P +TW+
Sbjct: 3963 GRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQ 4022
Query: 171 ----HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI 226
+++ V L+IS R+ +G Y C A N A + K+K+ V PP I
Sbjct: 4023 KEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNP-AGTALGKIKLNVQVPPVI 4081
Query: 227 S-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFN 285
S K ++V + LSCEA +P + W K+ + + R+ + G +L
Sbjct: 4082 SPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESI-RQRVLSSG---SLQIAF 4137
Query: 286 VSEKDYGNYTCVATNKLGNTNASITL 311
V D G+YTC+A N G+++ S L
Sbjct: 4138 VQPGDAGHYTCMAANVAGSSSTSTKL 4163
Score = 81.3 bits (199), Expect = 1e-15
Identities = 77/296 (26%), Positives = 117/296 (39%), Gaps = 35/296 (11%)
Query: 23 FLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDK 81
F + VP FP + V+V L C + + W L+ G
Sbjct: 1444 FNIDVLVPPTIIGTNFP---NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG--- 1497
Query: 82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM-- 139
DP V +L + ++N D+G Y C+V + + L + +PP I
Sbjct: 1498 ---DPNVELLDRGQVLH---LKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Query: 140 NISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQG--------FVSEDEYLEISD 191
N+++DI+V S + L C G P P +TW K+GQ ++ + +YL I
Sbjct: 1552 NVTTDISVLINSLIKLECETRGLPMPAITW----YKDGQPIMSSSQALYIDKGQYLHIPR 1607
Query: 192 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI----SKAKNTGVSVGQKGILSCEAS 247
+ S Y C N VA + + V PP I + N V + L C+A+
Sbjct: 1608 AQVSDSATYTCHVAN-VAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAA 1666
Query: 248 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
P W K+ + D +RIE G+ L + E D G Y CVAT+ G
Sbjct: 1667 GNPSPILTWLKDGVPVKAN-DNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAG 1719
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/223 (29%), Positives = 99/223 (44%), Gaps = 19/223 (8%)
Query: 102 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLA 159
I + D G Y C + K + + V VPP I + +S V + + L C
Sbjct: 1699 IMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHV 1758
Query: 160 IGRPEPTVTWRHLSVKEGQGFVSEDEY--------LEISDIKRDQSGEYECSALNDVAAP 211
G P PT+ W +K+GQ D + L I+ + +G Y C A N A
Sbjct: 1759 TGSPPPTIMW----LKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN-TAGD 1813
Query: 212 DVRKVKITVNYPPYI-SKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDG 269
++ ++TV+ PP I S + V V K + L C A+ +P W K++ + T
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGN 1873
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
++I++ GR+ L +D G YTCVATN G T I L+
Sbjct: 1874 LKIQSSGRV--LQIAKTLLEDAGRYTCVATNAAGETQQHIQLH 1914
Score = 80.5 bits (197), Expect = 2e-15
Identities = 73/279 (26%), Positives = 120/279 (43%), Gaps = 27/279 (9%)
Query: 45 VTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
+ V +G+S +L C + V W+ L +D I+ ++
Sbjct: 2302 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHIL----------QLK 2351
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN---ISSDITVNEGSSVTLLCLAI 160
N+ V D G Y C + L V PP I+ +I+V E +SV+L C A
Sbjct: 2352 NIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEAS 2411
Query: 161 GRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
G P P++TW +S+ +S L + + +G+Y C N AA + RK+
Sbjct: 2412 GIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRN--AAGEERKI 2469
Query: 217 -KITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 272
++V PP+I + ++ V Q L+CE + P+ E W K+ L + I
Sbjct: 2470 FGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQED-EAHHI 2528
Query: 273 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ GR +T NV G YTC+A++ G+ + S +L
Sbjct: 2529 ISGGRFLQIT--NVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Score = 79.7 bits (195), Expect = 3e-15
Identities = 66/229 (28%), Positives = 96/229 (41%), Gaps = 41/229 (17%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSD----ITVNEGSSVTLLCLAI 160
+ G Y C+ +V L V V P++ +S D I+V G VTL C
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVK 1104
Query: 161 GRPEPTVTW------------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 208
P P +TW RH + G ++I++ + SG Y C A N +
Sbjct: 1105 SLPPPIITWAKETQLISPFSPRHTFLPSGS--------MKITETRTSDSGMYLCVATN-I 1155
Query: 209 AAPDVRKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
A + VK+ V+ PP I + K+ V VGQ+ + C A P+ W K G
Sbjct: 1156 AGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSK-------GG 1208
Query: 268 DGMRIENKGRMS----TLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
M ++ + +S TL+ + D G YTCVATN G ITL+
Sbjct: 1209 STMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Score = 78.6 bits (192), Expect = 8e-15
Identities = 65/219 (29%), Positives = 84/219 (38%), Gaps = 11/219 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS--DITVNEGSSVTLLC 157
+ I V D G YTC + + V VPP I DITV VTL C
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLEC 3643
Query: 158 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
+ P P +TW L +S YL+I++ + Y C A N +A
Sbjct: 3644 KSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASN-IAGKTT 3702
Query: 214 RKVKITVNYPPYISKAKNTGVSVGQKG-ILSCEASAVPMAEFQWFKEETRLATGLDGMRI 272
R+ +TVN PP I + V + K +L C A VP W K+ LA I
Sbjct: 3703 REFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSI 3762
Query: 273 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G L + D G Y C+ATN G I L
Sbjct: 3763 LENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL 3798
Score = 77.8 bits (190), Expect = 1e-14
Identities = 74/277 (26%), Positives = 103/277 (37%), Gaps = 22/277 (7%)
Query: 45 VTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 104
++V GE TL C + + + T L + PR L + S+ I
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKETQLIS-----PFSPRHTFLPSG----SMKITE 1139
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPE 164
D G Y C T V L V VPP+I + V G V + C A G P
Sbjct: 1140 TRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPL 1199
Query: 165 PTVTWR---HLSVKEGQGFVSE-DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
P +TW + +G+ VS D L I +G Y C A N +A D ++ + V
Sbjct: 1200 PVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATN-IAGTDETEITLHV 1258
Query: 221 NYPPYISKAK---NTGVS---VGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
PP + + NT Q+ C A P +W L G+ I
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILE 1318
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G + L +V+ D G Y CVA N+ G T L
Sbjct: 1319 DGTL--LVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Score = 76.6 bits (187), Expect = 3e-14
Identities = 61/257 (23%), Positives = 108/257 (42%), Gaps = 17/257 (6%)
Query: 75 LYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV 134
L+ G + +P + IL + ++I +V YD G Y C + + +L V V
Sbjct: 1301 LHNGRELTGREPGISILEDGTL---LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 135 PPQIMNIS--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQG----FVSEDEYLE 188
PP I + ++++V L C G P P + W +V+ + V+ + L+
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILK 1417
Query: 189 ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCE 245
+ + +G Y C A+N +A + I V PP I + V + + L C+
Sbjct: 1418 LFRATPEDAGRYSCKAIN-IAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQ 1476
Query: 246 ASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN- 304
P + WFK+ L G + + ++G++ L N D G Y C +N G
Sbjct: 1477 VKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 305 -TNASITLYGPGAVIDG 320
+ +T+Y P ++ G
Sbjct: 1535 AKDIKLTIYIPPSIKGG 1551
Score = 75.1 bits (183), Expect = 9e-14
Identities = 56/216 (25%), Positives = 92/216 (42%), Gaps = 11/216 (5%)
Query: 102 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 161
I V + DEG Y C + ++ V PP ++ + +++TV G L CL I
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 162 RPEPTVTW----RHLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
+ +TW R + + E + LE+ +K + +GEY C ++ V
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSE-GGSSAASV 604
Query: 217 KITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 275
+TV PP ++ KN + G + + C A+ P + W + G R+ +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVND-MFIVGSHRYRMTSD 663
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G TL N + KD G Y C+A+N G + TL
Sbjct: 664 G---TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTL 696
Score = 74.7 bits (182), Expect = 1e-13
Identities = 62/233 (26%), Positives = 104/233 (44%), Gaps = 18/233 (7%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS--SDITVNEGSSVTLLC 157
+ I++ V D G YTC ++ + VPP I + +TV EG+ ++LLC
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 158 LAIGRPEPTVTWRHLS---VKEGQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 211
+ G P P + W+ + + G V S L+IS ++ + Y C A N VA
Sbjct: 2219 ESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN-VAGT 2277
Query: 212 DVRKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGL 267
++ + V P I+ + + + G+ L CE +P W K+ L
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKA- 2336
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVI 318
G+ I ++G + L +VS D G Y CVA N G T+ ++++ P ++I
Sbjct: 2337 KGVEILDEGHILQLKNIHVS--DTGRYVCVAVNVAGMTDKKYDLSVHAPPSII 2387
Score = 72.0 bits (175), Expect = 7e-13
Identities = 66/232 (28%), Positives = 96/232 (41%), Gaps = 15/232 (6%)
Query: 91 LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
L+ P + IQ D G YTC + T ++ L V PP + +D+++ G
Sbjct: 748 LIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIG 807
Query: 151 SSVTLLCLAIGRPEPTVTWRHLS---VKEGQGFVSEDEYLE-----ISDIKRDQSGEYEC 202
S+VTL C G PEPT+ WR L + VS L I ++ G Y C
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 203 SALNDVA-APDVRKVKITVNYPPYISKAKN-TGVSVGQKGILSCEASA-VPMAEFQWFKE 259
A N V +T P I + + V GQ+ L C A P+ E +W K
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKN 927
Query: 260 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L + + + G +L V +D G YTCVA+N G N + ++
Sbjct: 928 SAMLLQN-PYITVRSDG---SLHIERVQLQDGGEYTCVASNVAGTNNKTTSV 975
Score = 71.2 bits (173), Expect = 1e-12
Identities = 62/250 (24%), Positives = 101/250 (40%), Gaps = 39/250 (15%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI--------------SS 143
+++ I+ + D G YTC + +QVPP + +
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAK 2787
Query: 144 DITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDE--------YLEISDIKRD 195
D+ +N + ++L C P PT+TW K+G S D+ L+I K +
Sbjct: 2788 DVIIN--NPISLYCETNAAPPPTLTW----YKDGHPLTSSDKVLILPGGRVLQIPRAKVE 2841
Query: 196 QSGEYECSALNDVAAPDVRKVKITVNYPPYISKA-----KNTGVSVGQKGILSCEASAVP 250
+G Y C A+N+ A D + + V PP I A + V V + ++ C +S P
Sbjct: 2842 DAGRYTCVAVNE-AGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 251 MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--S 308
W K+ L D + + GR+ L N D G Y CVA N G+ +
Sbjct: 2901 APRNSWQKDGQPLLED-DHHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAKKYFN 2957
Query: 309 ITLYGPGAVI 318
+ ++ P +VI
Sbjct: 2958 LNVHVPPSVI 2967
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 25/220 (11%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI--SSDITVNEGSSVTLLC 157
I I V D YTC +L V PP + N + +ITV +GSS ++ C
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 158 LAIGRPEPTVTW----------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALND 207
+ G P P++ W HL+V G V L++ + + SG+Y C A N+
Sbjct: 3458 ITDGTPAPSMAWLRDGQPLGLDAHLTVST-HGMV-----LQLLKAETEDSGKYTCIASNE 3511
Query: 208 VAAPDVRKVKITVNYPPYIS---KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
A + + V PP+I+ + + V V L+C AS +P + W K+ L
Sbjct: 3512 -AGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
+++ G L +D G YTC+A++ G+
Sbjct: 3571 ---QTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607
Score = 63.2 bits (152), Expect = 3e-10
Identities = 60/237 (25%), Positives = 93/237 (39%), Gaps = 31/237 (13%)
Query: 99 SIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 154
++ I+N D G Y C S TD T R P++M + S++ V G
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI----EAPKLMVVQSELLVALGDITV 720
Query: 155 LLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEISDIKRDQ---SGEYECSALNDVAA 210
+ C G P P V W ++ F+ D L + I+ Q +G+Y C A+N+ A
Sbjct: 721 MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINE-AG 779
Query: 211 PDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
K+ + V PP +I + + + +G L C P +W + LD
Sbjct: 780 RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRR--------LDN 831
Query: 270 MRIENKG---------RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAV 317
M I ++ R L N+ D G Y C A N+ G + T+ G V
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLV 888
Score = 63.2 bits (152), Expect = 3e-10
Identities = 62/274 (22%), Positives = 119/274 (43%), Gaps = 23/274 (8%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
TF + +V++ +GE L C + ++ W + I+ A D VN
Sbjct: 4261 TFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS----------VNGH 4310
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM-NISSDITVNEGSSVT 154
++ ++I+ V D G Y C+ + + + V+ PP + S+ G +
Sbjct: 4311 SE--LVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAI 4368
Query: 155 LLCLAIGRPEPTVTWRHLSVK-EGQGFVSE--DEYLEISDIKRDQSGEYECSALNDVAAP 211
L C G P PT+ W V E + + + L I + +G+Y C A N+
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVV 4428
Query: 212 DVRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGM 270
+ R + +T+ PP I+ + T ++ G K IL+C+A+ P W ++ ++ D +
Sbjct: 4429 E-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD-DRV 4486
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
+ + ++L + ++D + CVA N +G+
Sbjct: 4487 NVLSN---NSLYIADAQKEDTSEFECVARNLMGS 4517
Score = 57.0 bits (136), Expect = 2e-08
Identities = 70/296 (23%), Positives = 113/296 (38%), Gaps = 30/296 (10%)
Query: 29 VPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPR 87
VP A P +V+V GE+ L C + T + WL + +G + R
Sbjct: 3243 VPPSVAGAEIPS---DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE-----R 3294
Query: 88 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRV-HLIVQVPPQIMNISSD-- 144
+ + N T + I D G YTC V T+ + R+ +L V V P I +
Sbjct: 3295 IRVSANGST---LNIYGALTSDTGKYTC-VATNPAGEEDRIFNLNVYVTPTIRGNKDEAE 3350
Query: 145 -ITVNEGSSVTLLCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGE 199
+ +S+ + C A G P P + W L + ++ + + I +
Sbjct: 3351 KLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAV 3410
Query: 200 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQW 256
Y C A N A D + + V PP + + T V G ++C P W
Sbjct: 3411 YTCVASNR-AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAW 3469
Query: 257 FKEETRLATGLDG-MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++ L GLD + + G + L +D G YTC+A+N+ G + L
Sbjct: 3470 LRDGQPL--GLDAHLTVSTHGMV--LQLLKAETEDSGKYTCIASNEAGEVSKHFIL 3521
Score = 56.2 bits (134), Expect = 4e-08
Identities = 43/168 (25%), Positives = 68/168 (40%), Gaps = 13/168 (7%)
Query: 50 GESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 109
G +A L C + T NR +D + + S+ I D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRK----------GVDIEISHRIRQLGNGSLAIYGTVNED 4413
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW 169
G YTC + + L +Q PP I + +N G + L C A G P+PT+TW
Sbjct: 4414 AGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITW 4473
Query: 170 R---HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR 214
H + + V + L I+D +++ + E+EC A N + + VR
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVR 4521
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 44 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 408 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 457
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 458 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 517
Query: 163 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 518 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 576
Query: 220 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 577 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 630
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L E+D G YTC A N+LG+ +A I L
Sbjct: 631 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 663
Score = 82.4 bits (202), Expect = 5e-16
Identities = 79/285 (27%), Positives = 112/285 (39%), Gaps = 34/285 (11%)
Query: 44 NVTVRQGESATLRCTIDDRVTRVAWLNRST------ILYAGNDKWSIDPRVIILVNTPTQ 97
+VTV G SA L C R R L AG S P +L
Sbjct: 677 DVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVL------ 730
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV--QVPPQIMNISSDITVNEGSSVTL 155
++V D+ PY C + + LIV PPQI + + + V EG V+L
Sbjct: 731 ---FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSL 787
Query: 156 LCLAI-GRPEPTVTWRHLSVKEGQGF-------VSEDEYLEISDIKRDQSGEYECSALND 207
C+ + GRP P W +K+G+ + D L + ++ +G Y C A N
Sbjct: 788 PCIVLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATN- 842
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVS-VGQKGILSCEASAVPMAEFQWFKEETRLATG 266
A R V++ V PP I ++ G L C AS VP W KE L +
Sbjct: 843 TAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSR 902
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +G TL S +D G Y C ATN +G ++ + L
Sbjct: 903 GPHYNVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 944
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 373 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 432
Query: 169 ----WRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
WR L G+ D LEIS I G Y+C A N V + V P
Sbjct: 433 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 491
Query: 225 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 492 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 547
Query: 284 FNVSEKDYGNYTCVATNKLGNTNASITLY 312
V+ +D GNY+C ATN++G ++TLY
Sbjct: 548 QGVAPEDAGNYSCQATNEVGTDQETVTLY 576
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 19/217 (8%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G YTC + ++ + L V PQ+ + D+TV G S L C A GRP PTVT
Sbjct: 642 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 701
Query: 169 WRH-----LSVKEGQGFVS-----EDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVK 217
WR L ++ G G S + L + + Y C A N ++
Sbjct: 702 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 761
Query: 218 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATG-LDGMRIEN 274
+T + PP I S A V GQ L C A P+ E W K+ L G +R +
Sbjct: 762 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD- 820
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+L ++ G Y+CVATN G+ + + L
Sbjct: 821 ----GSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL 853
Score = 75.5 bits (184), Expect = 7e-14
Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 16/208 (7%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW- 169
G Y+C + V L+VQVPP+I ++ NEG +L C+A G P PT+TW
Sbjct: 834 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 893
Query: 170 ---RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP-- 224
L+ + VS++ L I+ +G Y C+A N V ++++++VN P
Sbjct: 894 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSS-QEMRLSVNTKPRI 952
Query: 225 YISKAKNTGV------SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
+++ ++N V G++ L CEA P W K+ + + + G
Sbjct: 953 HMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG-- 1010
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTN 306
+L V D G+Y C A+N G+ +
Sbjct: 1011 -SLRLAQVQVGDSGHYECTASNPAGSAS 1037
Score = 72.4 bits (176), Expect = 6e-13
Identities = 55/233 (23%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 92 VNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGS 151
++ Q +++IQ V D G Y+C + V L PP + +++ + V G
Sbjct: 537 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE 596
Query: 152 SVTLLCLAIGRPEPTVTW-----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 206
L+C A G P P V W + EG S L I + +G Y C A+N
Sbjct: 597 EAVLVCEASGVPPPRVIWYRGGLEMILAPEG----SSSGKLRIPAAQERDAGTYTCRAVN 652
Query: 207 DVAAPDVRKVKITVNYPPYISK-AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR--- 262
++ ++++ V + P +++ ++ V +G+ +L+C A+ P W + + +
Sbjct: 653 ELGDASA-EIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLG 711
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 315
L G + L F +V+ +D Y C A N G A L G
Sbjct: 712 LRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 764
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/191 (23%), Positives = 72/191 (37%), Gaps = 25/191 (13%)
Query: 39 PKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 97
P A ++T +G A+L C + W + L + +++ +L+ P+
Sbjct: 863 PTATHHIT-NEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPS- 920
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-------MNISSDITVNEG 150
D G Y C+ + + L V P+I N+ +T G
Sbjct: 921 ---------AQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAG 971
Query: 151 SSVTLLCLAIGRPEPTVTWRHLS-----VKEGQGFVSEDEYLEISDIKRDQSGEYECSAL 205
VTL C A G P P VTW S + G + L ++ ++ SG YEC+A
Sbjct: 972 EEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS-LRLAQVQVGDSGHYECTAS 1030
Query: 206 NDVAAPDVRKV 216
N + R V
Sbjct: 1031 NPAGSASHRYV 1041
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 172 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 223
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 341 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 400
Query: 224 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 281
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 401 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 455
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ D G Y CVA+N G T AS+ L
Sbjct: 456 EISGIIPTDGGRYQCVASNANGVTRASVWL 485
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 44 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 574
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 575 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 634
Query: 163 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 635 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 693
Query: 220 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 694 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 747
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L E+D G YTC A N+LG+ +A I L
Sbjct: 748 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 780
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 95 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 1841 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 1900
Query: 151 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 206
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 1901 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 1960
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 1961 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 2019
Query: 265 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 2020 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 2065
Score = 92.0 bits (227), Expect = 7e-19
Identities = 83/302 (27%), Positives = 125/302 (41%), Gaps = 30/302 (9%)
Query: 21 LLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGN 79
LL L P PV GD + ++ VTV + +L+C + + V ++WL
Sbjct: 2836 LLVLTP---PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL------ 2884
Query: 80 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 139
+S PR+ +L + + + +V D Y C + L VQVPP+I
Sbjct: 2885 -PFSPSPRLQVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 2940
Query: 140 NISSD-ITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKR 194
+ + +T SSV+L C P P VTW + LS+ E + L++ +
Sbjct: 2941 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 3000
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAV 249
SG Y C ALN A D + V+++V PP +A V VG K +LSCE A+
Sbjct: 3001 SDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDAL 3059
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P W+K+ L + R L D G Y+C +N G +
Sbjct: 3060 PEPTVTWYKDGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 3116
Query: 310 TL 311
TL
Sbjct: 3117 TL 3118
Score = 90.5 bits (223), Expect = 2e-18
Identities = 70/247 (28%), Positives = 114/247 (46%), Gaps = 22/247 (8%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ + V V D G Y C+ + R L VQVPPQ+ + V G ++ L C+
Sbjct: 1083 SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCV 1142
Query: 159 AIGRPEPTVTW-RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
A G PEP ++W + V +G+G + + I+ +G Y C A N A D +V+
Sbjct: 1143 AEGNPEPQLSWSKDGVVLQGRG---PQGSVHFAAIRTSDAGRYRCEASNS-AGVDAWEVE 1198
Query: 218 ITVNYPPYISKAKNTGV---SVGQKGILSCEASAVPMAEFQWFK-EETRLATGLDGMRIE 273
+ V PP+ + +G+ G+ L C A P + W K + G G+ +
Sbjct: 1199 LRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVL 1258
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGPGAV--------IDGVNS 323
+G +L +VS D G+Y C ATN++G+T+ A + +Y P ++ + G+
Sbjct: 1259 EEG---SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAG 1315
Query: 324 ASRALAC 330
S L C
Sbjct: 1316 QSLTLEC 1322
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 4061
Query: 160 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 4062 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 4120
Query: 216 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 4121 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 4175
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+ STL VS +D G Y C A N++G T A
Sbjct: 4176 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 4208
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 3889
Query: 169 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 3890 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 3948
Query: 225 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 3949 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 4004
Query: 284 FNVSEKDYGNYTCVATNKLGN 304
+ S +D GNY C+A N G+
Sbjct: 4005 AHASPEDAGNYLCIAKNSAGS 4025
Score = 82.4 bits (202), Expect = 5e-16
Identities = 79/285 (27%), Positives = 112/285 (39%), Gaps = 34/285 (11%)
Query: 44 NVTVRQGESATLRCTIDDRVTRVAWLNRST------ILYAGNDKWSIDPRVIILVNTPTQ 97
+VTV G SA L C R R L AG S P +L
Sbjct: 794 DVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVL------ 847
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV--QVPPQIMNISSDITVNEGSSVTL 155
++V D+ PY C + + LIV PPQI + + + V EG V+L
Sbjct: 848 ---FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSL 904
Query: 156 LCLAI-GRPEPTVTWRHLSVKEGQGF-------VSEDEYLEISDIKRDQSGEYECSALND 207
C+ + GRP P W +K+G+ + D L + ++ +G Y C A N
Sbjct: 905 PCIVLAGRPLPERHW----LKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATN- 959
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVS-VGQKGILSCEASAVPMAEFQWFKEETRLATG 266
A R V++ V PP I ++ G L C AS VP W KE L +
Sbjct: 960 TAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSR 1019
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +G TL S +D G Y C ATN +G ++ + L
Sbjct: 1020 GPHYNVSKEG---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRL 1061
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 43 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 99
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 3040 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 3086
Query: 100 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 156
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 3145
Query: 157 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 3146 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 3203
Query: 213 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 3204 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 3262
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G + +L + D G YTCVA N G
Sbjct: 3263 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 490 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 549
Query: 169 ----WRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
WR L G+ D LEIS I G Y+C A N V + V P
Sbjct: 550 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 608
Query: 225 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 609 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 664
Query: 284 FNVSEKDYGNYTCVATNKLGNTNASITLY 312
V+ +D GNY+C ATN++G ++TLY
Sbjct: 665 QGVAPEDAGNYSCQATNEVGTDQETVTLY 693
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 166
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 2230 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 2289
Query: 167 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 2290 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 2348
Query: 223 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 2349 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 2407
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 317
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 2408 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 2446
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/217 (29%), Positives = 91/217 (41%), Gaps = 19/217 (8%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G YTC + ++ + L V PQ+ + D+TV G S L C A GRP PTVT
Sbjct: 759 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVT 818
Query: 169 WRH-----LSVKEGQGFVS-----EDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVK 217
WR L ++ G G S + L + + Y C A N ++
Sbjct: 819 WRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLI 878
Query: 218 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATG-LDGMRIEN 274
+T + PP I S A V GQ L C A P+ E W K+ L G +R +
Sbjct: 879 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRAD- 937
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+L ++ G Y+CVATN G+ + + L
Sbjct: 938 ----GSLHLDRALQEHAGRYSCVATNTAGSQHRDVEL 970
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 165
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 1567 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 1626
Query: 166 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 221
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 1627 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 1685
Query: 222 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 1686 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 1742
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 321
+TL +V G + C ATN+ G A + + G GV
Sbjct: 1743 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 1785
Score = 76.3 bits (186), Expect = 4e-14
Identities = 79/312 (25%), Positives = 127/312 (40%), Gaps = 34/312 (10%)
Query: 44 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 2079 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 2129
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 162
DV+D G YTC +L V V P + S +TV EG +L C G
Sbjct: 2130 RADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGV 2189
Query: 163 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 212
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 2190 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 2244
Query: 213 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 268
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 2245 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 2303
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 326
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 2304 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 2361
Query: 327 ALACLWLSGTLL 338
A L TLL
Sbjct: 2362 ITAALHSPLTLL 2373
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 155
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 3367 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 3426
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 211
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 3427 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 3481
Query: 212 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 3482 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 3537
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+EN R + + + +D G YTC+A + G
Sbjct: 3538 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 3566
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 170
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 3982
Query: 171 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 227
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 3983 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 4041
Query: 228 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 286
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 4042 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 4098
Query: 287 SEKDYGNYTCVATNKLGNTNASITL 311
+D G YTC A N +G + L
Sbjct: 4099 EGQDAGTYTCTAENAVGRARRRVHL 4123
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 147
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 2592 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 2651
Query: 148 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 199
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 2652 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 2707
Query: 200 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 238
Y C A N VA D + + + PP K + +
Sbjct: 2708 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766
Query: 239 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 2767 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 2823
Query: 299 TNKLG 303
+N++G
Sbjct: 2824 SNEVG 2828
Score = 72.8 bits (177), Expect = 4e-13
Identities = 66/251 (26%), Positives = 97/251 (38%), Gaps = 68/251 (27%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 170
G Y+C + V L+VQVPP+I ++ NEG +L C+A G P PT+TW
Sbjct: 951 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 1010
Query: 171 -----------HLSV-KEGQ----------------------GFVSE------------- 183
H +V KEG GF S+
Sbjct: 1011 KETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSK 1070
Query: 184 ---DEY-------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT- 232
+EY L ++ ++ SG YEC+A N + R V + V PP +
Sbjct: 1071 YVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYV-LGVQVPPQVQPGPRVL 1129
Query: 233 GVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYG 292
V VG+ L+C A P + W K DG+ ++ +G ++ F + D G
Sbjct: 1130 KVLVGEALDLNCVAEGNPEPQLSWSK---------DGVVLQGRGPQGSVHFAAIRTSDAG 1180
Query: 293 NYTCVATNKLG 303
Y C A+N G
Sbjct: 1181 RYRCEASNSAG 1191
Score = 72.4 bits (176), Expect = 6e-13
Identities = 55/233 (23%), Positives = 96/233 (41%), Gaps = 14/233 (6%)
Query: 92 VNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGS 151
++ Q +++IQ V D G Y+C + V L PP + +++ + V G
Sbjct: 654 IHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE 713
Query: 152 SVTLLCLAIGRPEPTVTW-----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN 206
L+C A G P P V W + EG S L I + +G Y C A+N
Sbjct: 714 EAVLVCEASGVPPPRVIWYRGGLEMILAPEG----SSSGKLRIPAAQERDAGTYTCRAVN 769
Query: 207 DVAAPDVRKVKITVNYPPYISK-AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR--- 262
++ ++++ V + P +++ ++ V +G+ +L+C A+ P W + + +
Sbjct: 770 ELGDASA-EIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLG 828
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 315
L G + L F +V+ +D Y C A N G A L G
Sbjct: 829 LRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 881
Score = 72.4 bits (176), Expect = 6e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 166
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 2417 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 2476
Query: 167 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 2477 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 2535
Query: 223 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 268
P I S + V+V L CEA A P W K+ +L G
Sbjct: 2536 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 2595
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G++I N ++D G YTCV TN+LG
Sbjct: 2596 GLQI-----------LNAQKEDAGQYTCVVTNELG 2619
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 141
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 3440 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 3499
Query: 142 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 198
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 3500 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 3555
Query: 199 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 254
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 3556 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 3613
Query: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 311
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 3614 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 3670
Query: 312 ------YGPGAVIDGVNSAS 325
GP AV VN +
Sbjct: 3671 TVPTIRSGPPAVNVSVNQTA 3690
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 155
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 2806 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 2865
Query: 156 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 2866 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925
Query: 212 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 2926 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 2984
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ TL D G YTC A N G + L
Sbjct: 2985 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 3023
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/229 (25%), Positives = 87/229 (37%), Gaps = 27/229 (11%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN--EGSSVTLL 156
S+ + +V D G Y C + + R L+V VPP I V+ G S+TL
Sbjct: 1262 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 1321
Query: 157 CLAIGRPEPTVTWRH-------------------LSVKEGQGFVSEDEYLEISDIKRDQS 197
C A G P P + W G + E + L I+ S
Sbjct: 1322 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDS 1381
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEF 254
G Y C A N R + V PP + A +G G L C S VP +
Sbjct: 1382 GLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQV 1440
Query: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+W K+ + G ++++ G++ +T +V D G Y CVA + G
Sbjct: 1441 EWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG--DEGRYQCVAFSPAG 1487
Score = 69.3 bits (168), Expect = 5e-12
Identities = 82/314 (26%), Positives = 127/314 (40%), Gaps = 33/314 (10%)
Query: 25 VPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWS 83
VPT +RSG P A+ NV+V Q +A L C D V+W D+
Sbjct: 3672 VPT---IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVP 3712
Query: 84 IDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS 143
+DPR P + S+ IQ V D G Y C L V PP I S
Sbjct: 3713 LDPRSPRFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPS 3771
Query: 144 DITVNEGSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQS 197
++T+ + L C A G P+P V W +++G + L ++ S
Sbjct: 3772 NLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 3831
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQW 256
++EC N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W
Sbjct: 3832 AQFECVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSW 3890
Query: 257 FKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPG 315
K +L G R+ G + + G YTC A N G + + L
Sbjct: 3891 SKAGAQLGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQAS 3947
Query: 316 AVIDGVNSASRALA 329
V+ + S RA+A
Sbjct: 3948 PVVKPLPSVVRAVA 3961
Score = 67.8 bits (164), Expect = 1e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 2044 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 2103
Query: 169 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 2104 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGHSEKHYNLNVWVAP 2162
Query: 225 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 281
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 2163 VFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 2222
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++++ G YTC +N +GN++ + L
Sbjct: 2223 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 2250
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 157
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 1465 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 1524
Query: 158 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 1525 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 1583
Query: 214 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 1584 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 1643
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+E G S L + E G Y+CVA++ G
Sbjct: 1644 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 1674
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 47 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 3280
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 161
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 3281 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 3339
Query: 162 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 3340 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 3398
Query: 218 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 273
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 3399 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 3453
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +L V D G Y+CVA ++ G L
Sbjct: 3454 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 3488
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 3696
Query: 160 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 3697 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 3755
Query: 216 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 270
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 3756 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 3815
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 319
N L +D + CV +N++G + +T++ P + D
Sbjct: 3816 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 3861
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 166
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 4191 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 4249
Query: 167 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 4250 IHW----IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 4305
Query: 220 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 273
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 4306 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 4361
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+L NV D G Y CVA N LG+ A
Sbjct: 4362 ------SLWLENVETGDAGTYDCVAHNLLGSATA 4389
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ I + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 4272 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 4331
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 211
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 4332 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 4387
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 252
R + V P S TGV G+K G+ + S + A
Sbjct: 4388 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 4428
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 172 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 223
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 458 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 517
Query: 224 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 281
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 518 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 572
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ D G Y CVA+N G T AS+ L
Sbjct: 573 EISGIIPTDGGRYQCVASNANGVTRASVWL 602
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 17 VSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTIL 75
V+ +++ LV PV F ++TVR G+ LRC T + WL L
Sbjct: 4296 VAKKVVILVLQSAPV------FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 4349
Query: 76 YAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP 135
A + T S+ ++NV+ D G Y C T+R L+V+
Sbjct: 4350 RASR-----------RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGE 4398
Query: 136 PQ 137
PQ
Sbjct: 4399 PQ 4400
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 98.2 bits (243), Expect = 9e-21
Identities = 76/273 (27%), Positives = 115/273 (42%), Gaps = 22/273 (8%)
Query: 44 NVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
NVTV GE+A L C + + + W+ W + P V S+ I
Sbjct: 524 NVTVSPGETAVLSCRVLGEAPYNLTWVR----------DWRVLPASTGRVAQLADLSLEI 573
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ D G Y C N + V L+V+ PQ+ +S ++G V + C A G
Sbjct: 574 SGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGY 633
Query: 163 PEPTVTWRHLS---VKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
P P ++W S ++ + V L I + + +G Y C A N+V D V +
Sbjct: 634 PTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGT-DQETVTLY 692
Query: 220 VNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP +S V+VG++ +L CEAS VP W++ GL+ +
Sbjct: 693 YTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR------GGLEMILAPEGSSS 746
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L E+D G YTC A N+LG+ +A I L
Sbjct: 747 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQL 779
Score = 80.9 bits (198), Expect = 2e-15
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
+EG Y C+ + ++ ++V PP + + ++TV+ G + L C +G +T
Sbjct: 489 EEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLT 548
Query: 169 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W R L G+ D LEIS I G Y+C A N V + V P
Sbjct: 549 WVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRA-SVWLLVREAP 607
Query: 225 YIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+S + S G + +SC AS P W +E L + ++ +G TL
Sbjct: 608 QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQG---TLII 663
Query: 284 FNVSEKDYGNYTCVATNKLGNTNASITLY 312
V+ +D GNY+C ATN++G ++TLY
Sbjct: 664 QGVAPEDAGNYSCQATNEVGTDQETVTLY 692
Score = 52.0 bits (123), Expect = 8e-07
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 15/150 (10%)
Query: 172 LSVKEGQGFVSEDEYL--------EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 223
L ++ G+ + E+ + EI + + G YEC+A++ + + + P
Sbjct: 457 LQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPP 516
Query: 224 PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL--ATGLDGMRIENKGRMSTL 281
P + A N VS G+ +LSC W ++ L +TG R+ +S L
Sbjct: 517 PQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTG----RVAQLADLS-L 571
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ D G Y CVA+N G T AS+ L
Sbjct: 572 EISGIIPTDGGRYQCVASNANGVTRASVWL 601
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 97.1 bits (240), Expect = 2e-20
Identities = 75/277 (27%), Positives = 115/277 (41%), Gaps = 19/277 (6%)
Query: 44 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
++ V GESA C + + R+ W + + G + + + NTP + I
Sbjct: 6279 SIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY-----TITCVGNTP---HLRI 6330
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ-IMNISSDITVNEGSSVTLLCLAIG 161
V D G YTC D L V+ PP+ + + + +G S+ L C G
Sbjct: 6331 LKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISG 6390
Query: 162 RPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
PE V+W H S K F++ L I++ + SG+Y C A N V
Sbjct: 6391 SPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASC-S 6449
Query: 216 VKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
+TV PP + K G G IL CE S P E W K+ ++ +I +
Sbjct: 6450 TALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNS-KKFKITS 6508
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
K ++L N+ D G Y C ATN++G+ S ++
Sbjct: 6509 KHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 93.6 bits (231), Expect = 2e-19
Identities = 71/283 (25%), Positives = 117/283 (41%), Gaps = 21/283 (7%)
Query: 38 FPKAMDNVTVRQGESATLRCTID-DRVTRVAWLNRSTILYAGND-KWSIDPRVIILVNTP 95
F K ++ V + L C +D DR V W L G D K + ++ L
Sbjct: 3646 FIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE--- 3702
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQ-IMNISSDITVNEGSSVT 154
I + D G Y C+ + + + V+ PP + + + G S
Sbjct: 3703 ------IPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESAR 3756
Query: 155 LLCLAIGRPEPTVTWRHLSVKEGQG------FVSEDEYLEISDIKRDQSGEYECSALNDV 208
L C G P VTW + + + FV+ + L+I+D+K + SG Y C A+NDV
Sbjct: 3757 LHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDV 3816
Query: 209 AAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
+ D +I + PP +I + + G +L CE S E WFK++ ++ +
Sbjct: 3817 GS-DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSS- 3874
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT 310
R+ ++ + L F+ + D G Y CV N++G T
Sbjct: 3875 KKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMAT 3917
Score = 90.9 bits (224), Expect = 2e-18
Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 18/284 (6%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 96
F ++++TV GE A L+ +I+ + V WL + ++ + R+ + N T
Sbjct: 5612 FVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESE----NIRITFVENVAT 5667
Query: 97 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLL 156
+ + + G Y C ++ D + + L+V P I+ + +TV G + TL
Sbjct: 5668 ---LQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLE 5724
Query: 157 CLAIGRPEPTVTWRH------LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV-- 208
C G PE +V W S K F ++ L I ++R +G Y N+V
Sbjct: 5725 CKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGK 5784
Query: 209 -AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
+ V V P + + KNTG +G IL C+ + WF E+T++ +G
Sbjct: 5785 SSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGA 5844
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ + TL ++ D GNYTCVA N G+ L
Sbjct: 5845 K-YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 5887
Score = 85.9 bits (211), Expect = 5e-17
Identities = 71/283 (25%), Positives = 119/283 (42%), Gaps = 18/283 (6%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
+F + D+V V G S T I +V W S L G + I L +
Sbjct: 6835 SFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG------ESCNISLEDFV 6888
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
T+ + V + G Y+C V D + HL V+ P + +D +V GS + L
Sbjct: 6889 TELELF--EVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVL 6946
Query: 156 LCLAIGRPEPTVTW---RHLSVKEGQGFVSEDE---YLEISDIKRDQSGEYECSALNDVA 209
G P +V+W +L + + ++ E LEI + + +Y C N+ A
Sbjct: 6947 EATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENE-A 7005
Query: 210 APDVRKVKITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
D+ + ++V PPY I ++ +G+ L C+ P W+KE T+L +
Sbjct: 7006 GQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSA-P 7064
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+++ K +++L V D G Y+C A N +G +S L
Sbjct: 7065 AYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL 7107
Score = 85.5 bits (210), Expect = 6e-17
Identities = 56/215 (26%), Positives = 96/215 (44%), Gaps = 9/215 (4%)
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 163
+VD G YTC V + + HL ++ P + + +D ++ +G + L G P
Sbjct: 7836 DVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTP 7895
Query: 164 EPTVTWRH--LSVKEGQ----GFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
+VTW+ ++V Q + LEI + +G+Y C + + + D +
Sbjct: 7896 PISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNC-YIENASGKDSCSAQ 7954
Query: 218 ITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 276
I + PPY + + + VSVG L C+ + P W+K +T+L ++ +
Sbjct: 7955 ILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRP-TTTYKMHFRN 8013
Query: 277 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++TL F V D G Y C A N +G +AS L
Sbjct: 8014 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFL 8048
Score = 84.0 bits (206), Expect = 2e-16
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 9/211 (4%)
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 163
N+D+ G YTC V + + L V+ P + SD +V G S+ L G
Sbjct: 5954 NIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTL 6013
Query: 164 EPTVTWR----HLSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
+VTW+ +++ E V+ ++ LEI + + +G+Y C N+ A DV
Sbjct: 6014 PISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENE-AGRDVCGAL 6072
Query: 218 ITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 276
++ PPY +++ + +VG L C+ + P W+K +T+L + R
Sbjct: 6073 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPE-YRTYFTN 6131
Query: 277 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
++TL F V+ D G YTC A N +G ++
Sbjct: 6132 NVATLVFNKVNINDSGEYTCKAENSIGTASS 6162
Score = 81.6 bits (200), Expect = 9e-16
Identities = 78/307 (25%), Positives = 119/307 (38%), Gaps = 31/307 (10%)
Query: 36 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 94
AT + +++ V G++ TL CT+ W L + N K+ I N
Sbjct: 7586 ATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDN-KYKIS-----FFNK 7639
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGS 151
+ I+ NV D G Y+ VQ + L V VPP + GS
Sbjct: 7640 VSGLKII--NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGS 7697
Query: 152 SVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYE 201
SV + C G P +V+W H EG S +Y L ++ ++ SG+Y
Sbjct: 7698 SVVMECKVYGSPPISVSWFH----EGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYT 7753
Query: 202 CSALNDVAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 260
C A N +A D +TV PP ++ K V G + P WFK
Sbjct: 7754 CIATN-MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS 7812
Query: 261 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY--GPGAVI 318
+ L G D + + ++ L F+V G YTC+ +N+ G + + LY P +
Sbjct: 7813 SELVPG-DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFV 7871
Query: 319 DGVNSAS 325
+N S
Sbjct: 7872 KRLNDYS 7878
Score = 80.1 bits (196), Expect = 3e-15
Identities = 71/286 (24%), Positives = 118/286 (41%), Gaps = 27/286 (9%)
Query: 37 TFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
+F K ++N T SAT + T+ + WL IL ++ + I V++
Sbjct: 5049 SFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVY------ISFVDSV 5102
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
++ I++VD G YTC + ++ + L+VQ P QI+ + + V E +TL
Sbjct: 5103 A--TLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTL 5160
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSAL 205
C+ G PE V W +K+G+ V + I + + SG+Y
Sbjct: 5161 ECVVAGTPELKVKW----LKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 5216
Query: 206 NDVAAP--DVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR 262
ND + D + N PP + K +G + C+ S QWFK+
Sbjct: 5217 NDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKE 5276
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 308
++T R+ R +L N+ +D NYTC +N G+ S
Sbjct: 5277 ISTSAK-YRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACS 5321
Score = 79.7 bits (195), Expect = 3e-15
Identities = 61/236 (25%), Positives = 97/236 (41%), Gaps = 10/236 (4%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLLC 157
S+ + V D G YTC V +L V+ P + + + +G + L C
Sbjct: 4262 SLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLAC 4321
Query: 158 LAIGRPEPTVTW----RHL--SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
G P +TW R + S K FV L ++D+ + SGEY C A N+ +
Sbjct: 4322 KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSD 4381
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ I P + + K V +L E + P E WFK+ T L +G +
Sbjct: 4382 HCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK-YK 4440
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAVIDGVNSAS 325
+ + +L D G Y C TN++G++ +A +TL P + I + S S
Sbjct: 4441 TFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTS 4496
Score = 79.3 bits (194), Expect = 5e-15
Identities = 66/289 (22%), Positives = 115/289 (39%), Gaps = 28/289 (9%)
Query: 38 FPKAMDNVTVRQGESATLRCTID--DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
F K + +++ G+ L+ TI+ + ++ V + ++ I+ ++ W + +
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW--------ISYSE 7545
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
++ V+ + G YTC ++ D + L V P I+ I V G + TL
Sbjct: 7546 NIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTL 7605
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSAL 205
C G PE + W K+G+ S+++Y L+I ++ SG Y
Sbjct: 7606 ECTVAGTPELSTKW----FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQ 7661
Query: 206 NDVAAPDVR---KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETR 262
N V +V P + K K T G ++ C+ P WF E
Sbjct: 7662 NPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNE 7721
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+++G + LT + E D G+YTC+ATN G+ S L
Sbjct: 7722 ISSGRK-YQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPL 7769
Score = 77.8 bits (190), Expect = 1e-14
Identities = 76/289 (26%), Positives = 123/289 (42%), Gaps = 33/289 (11%)
Query: 37 TFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYA-GNDKWSIDPRVIILVNT 94
TF K +D++ G++ TL+ + V W+ ++ G K S V +L+
Sbjct: 3925 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLI-- 3982
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 154
I +V + G YTC + + +TS LIV+ P +I+ + I V G T
Sbjct: 3983 -------IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPAT 4035
Query: 155 LLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSA 204
L G PE W K+G+ V+ +Y L+ + SG+Y
Sbjct: 4036 LEYTVAGTPELKPKW----YKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEI 4091
Query: 205 LNDVAAPDVRKVKITV---NYPPYISK-AKNTGVSVGQKGILSCE-ASAVPMAEFQWFKE 259
N+V + + TV + P+ +K +N V L C+ A ++PM WFK+
Sbjct: 4092 SNEVGSSSC-ETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPM-RVSWFKD 4149
Query: 260 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 308
+A D RI ++L V D GN+TC ATN +G+ ++S
Sbjct: 4150 GKEIAAS-DRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 4197
Score = 77.0 bits (188), Expect = 2e-14
Identities = 61/243 (25%), Positives = 98/243 (40%), Gaps = 12/243 (4%)
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV-NEGSSVT 154
T S+ + D G Y C + D TS+ L V+ PPQ + S + V G S T
Sbjct: 4821 TSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTT 4880
Query: 155 LLCLAIGRPEPTVTW----RHLSV--KEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 208
C G P+ V+W ++ K G F+ +IS + + SG Y C A ND
Sbjct: 4881 FECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDA 4940
Query: 209 AAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
+++ V PP +I + K V L CE + P E W K + +
Sbjct: 4941 GTASC-SIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSS- 4998
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS--ITLYGPGAVIDGVNSAS 325
+ ++ + L D G Y C+ +N+ G+ + S + L P + I + + +
Sbjct: 4999 KKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTT 5058
Query: 326 RAL 328
L
Sbjct: 5059 TVL 5061
Score = 76.6 bits (187), Expect = 3e-14
Identities = 60/227 (26%), Positives = 94/227 (41%), Gaps = 10/227 (4%)
Query: 102 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 161
+ N+ V D G YTC +S L V+ PP I +G+ V L C G
Sbjct: 7365 MHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQG 7424
Query: 162 RPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQS--GEYECSALNDVAAPDVRK 215
P V+W R L + +SE+ I + D + GEY+C A NDV + D
Sbjct: 7425 TPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCV 7483
Query: 216 VKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
I + PP ++ K + VG++ L WFK++ + D + I
Sbjct: 7484 GSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 7543
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGPGAVID 319
++TL F V + G YTC N G A++++ P +++
Sbjct: 7544 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVE 7590
Score = 75.5 bits (184), Expect = 7e-14
Identities = 72/288 (25%), Positives = 114/288 (39%), Gaps = 21/288 (7%)
Query: 36 ATFPKAMDNVTVRQGESATLRCTIDDRVTRVA-WLNRSTILYAGNDKWSIDPRVIILVNT 94
AT + ++ V QG+ ATL+ A W L G+ K+ I T
Sbjct: 4579 ATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS-KYKISV-------T 4630
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGS 151
T + I + + D G YT VQ D + + + V +PP + +GS
Sbjct: 4631 DTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGS 4690
Query: 152 SVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSAL 205
+ L C+ G ++ W + +S E F D +LEIS ++ SG Y CSA
Sbjct: 4691 FIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSAT 4750
Query: 206 NDVAAPDVRKVKITVNYPPY-ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
N A + +TV PPY + K ++ V+ + L +WFK+ L
Sbjct: 4751 NK-AGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH 4809
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
+G + ++L F D G Y C +N +G + TL+
Sbjct: 4810 SGA-ARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF 4856
Score = 75.1 bits (183), Expect = 9e-14
Identities = 70/286 (24%), Positives = 113/286 (39%), Gaps = 25/286 (8%)
Query: 47 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWS---IDPRVIILVNTPTQYSIMI 102
V+ G+S+ L C I RV W L A +DK+ ID +I +N
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHELPA-SDKYRMTFIDSVAVIQMN--------- 5484
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
N+ D G + C Q + +IV+ PP + + + + V+L C G
Sbjct: 5485 -NLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 5543
Query: 163 PEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQS--GEYECSALNDVAAPDVRKV 216
P V W R L + S++ + I + D S GEY C A N+V + D
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS-DTCVC 5602
Query: 217 KITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 275
+ + PP ++SK + V G+ L QW KE+ + + +RI
Sbjct: 5603 TVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFV 5662
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVID 319
++TL F + G Y C N G A++ + P +++
Sbjct: 5663 ENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVE 5708
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/292 (23%), Positives = 114/292 (39%), Gaps = 32/292 (10%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 96
F K ++ V V G+SA+L+C + V+W Y G+ K + P ++
Sbjct: 7963 FVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW-------YKGDTK--LRPTTTYKMHFRN 8013
Query: 97 QYSIMIQN-VDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGSS 152
+ ++ N VD+ D G Y C + ++ L VQ +PP D+ G
Sbjct: 8014 NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLP 8073
Query: 153 VTLLCLAIGRPEPTVTWRHLSVKEGQ----------GFVSEDEYLEISDIKRDQSGEYEC 202
V C G +V+W K+G+ F+ L I R +G+Y C
Sbjct: 8074 VVFDCAISGSEPISVSW----YKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSC 8129
Query: 203 SALNDV--AAPDVRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 259
+A N + A+ R + PP+ + VG+ C + + W K+
Sbjct: 8130 TATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKD 8189
Query: 260 ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +G +I + LT V + D G YTC A N++G + + L
Sbjct: 8190 SREIRSG-GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 8240
Score = 73.6 bits (179), Expect = 2e-13
Identities = 68/285 (23%), Positives = 112/285 (39%), Gaps = 26/285 (9%)
Query: 40 KAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQY 98
+ ++ + V G A C I R W +Y +DK SI I
Sbjct: 3460 RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYE-SDKCSIRSSKYIS------- 3511
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ--VPPQIMNISSDITVNEGSSVTLL 156
S+ I V D G YTC + + L V PP ++ +T G + +
Sbjct: 3512 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFI 3571
Query: 157 CLAIGRPEPTVTWRHLSVKEGQGF-------VSEDE---YLEISDIKRDQSGEYECSALN 206
C G P W+ K+G +S+ E LE+S++ G Y C A N
Sbjct: 3572 CTVTGTPVIETIWQ----KDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASN 3627
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
A + I ++ P +I + + ++ +K L C+ W K+ +L G
Sbjct: 3628 KFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPG 3687
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
D +I + +++TL KD G Y C A+N+ G+++ S T+
Sbjct: 3688 KD-YKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATV 3731
Score = 72.4 bits (176), Expect = 6e-13
Identities = 66/285 (23%), Positives = 114/285 (40%), Gaps = 20/285 (7%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDD-RVTRVAWL-NRSTILYAGNDKWSIDPRVIILVNTP 95
F K + + + G++ LR ++ + V WL +R ++ + S + R+ + N
Sbjct: 6553 FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVI-----RESENTRISFIDNIA 6607
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
T + + + + + G Y C ++ D + L V P +I+ +TV G+ L
Sbjct: 6608 T---LQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFAL 6664
Query: 156 LCLAIGRPEPTVTW----RHLSV--KEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVA 209
C+ G PE + W R LS K F+++ L+I + G Y N V
Sbjct: 6665 ECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724
Query: 210 APDVR---KVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
+ V + P +I K K+ +G +L C S WF++ + +G
Sbjct: 6725 KSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSG 6784
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ + TL + D G YTCVA N G+ S L
Sbjct: 6785 -PKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 6828
Score = 72.0 bits (175), Expect = 7e-13
Identities = 66/289 (22%), Positives = 113/289 (39%), Gaps = 20/289 (6%)
Query: 45 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
+ +R G+S T C I RV+W GN+ +I I ++ + I
Sbjct: 4871 LVLRNGQSTTFECQITGTPKIRVSWY------LDGNEITAIQKHGISFIDGLATFQISGA 4924
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP 163
V+ + G Y C + D + + L V+ PP + + V + S V L C G P
Sbjct: 4925 RVE--NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTP 4982
Query: 164 EPTVTW--RHLSVKEGQGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
VTW + ++ + + D L I+ +GEY+C N+ + +
Sbjct: 4983 PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSC-STR 5041
Query: 218 ITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 276
+ + PP +I K +NT + + P W K++ L D + I
Sbjct: 5042 VALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDED-DNVYISFVD 5100
Query: 277 RMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVIDGVNS 323
++TL +V G YTC A N+ G A + + P +++ S
Sbjct: 5101 SVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKS 5149
Score = 72.0 bits (175), Expect = 7e-13
Identities = 67/282 (23%), Positives = 102/282 (36%), Gaps = 19/282 (6%)
Query: 48 RQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVD 106
+QGES L C I +V+W + L+ + W + I V T I
Sbjct: 6377 KQGESIQLECKISGSPEIKVSWFRNDSELH---ESWKYNMSFINSVALLT-----INEAS 6428
Query: 107 VYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPT 166
D G Y C + L V+ PP S + +GS V L C G P
Sbjct: 6429 AEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFE 6488
Query: 167 VTW--RHLSVKEGQGFVSE----DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITV 220
V W V+ + F D L I +++ GEY C A N+V + D +
Sbjct: 6489 VVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGS-DTCSCSVKF 6547
Query: 221 NYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMS 279
PP ++ K +T +G L W K+ + + RI ++
Sbjct: 6548 KEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIA 6607
Query: 280 TLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVID 319
TL + + G Y C N G +A +T+ P +I+
Sbjct: 6608 TLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIE 6649
Score = 70.9 bits (172), Expect = 2e-12
Identities = 70/281 (24%), Positives = 112/281 (39%), Gaps = 25/281 (8%)
Query: 45 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGND-KWSIDPRVIILVNTPTQYSIMI 102
+TV GE+ TL C + V W +L + K+S ++ S+ I
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS---------SLRI 5763
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIV----QVPPQIMNISSDITVNEGSSVTLLCL 158
+V+ D G YT VQ +N K+S ++ VPP + G+S L C
Sbjct: 5764 LSVERQDAGTYTFQVQ-NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK 5822
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYECSALNDVAAPD 212
G +V W H K G + + L+++ + G Y C A N VA D
Sbjct: 5823 VAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN-VAGSD 5881
Query: 213 VRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ +TV PP ++ + + V G+ + P + WF+ L G D
Sbjct: 5882 ECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCN 5940
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
I + ++ L FN+ G YTCV +N G + + L+
Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLF 5981
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/220 (25%), Positives = 91/220 (41%), Gaps = 8/220 (3%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
SI I NVD D G Y C D T + ++ PP+ + SDI+ G V L
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTT 7514
Query: 159 AIGRPEPTVTW---RHLSVKEGQG-FVSEDE---YLEISDIKRDQSGEYECSALNDVAAP 211
G +V W + V+E ++S E L+ S ++ +G+Y C ND
Sbjct: 7515 IEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQ 7574
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ + + K ++ V+ G L C + P +WFK+ L T + +
Sbjct: 7575 ECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKEL-TSDNKYK 7633
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
I ++S L NV+ D G Y+ N +G + + +L
Sbjct: 7634 ISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 7673
Score = 69.7 bits (169), Expect = 4e-12
Identities = 72/291 (24%), Positives = 104/291 (35%), Gaps = 30/291 (10%)
Query: 38 FPKAMDNVTVRQGESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDP--RVIILVN 93
F ++ + G+S +L+C + +T V+W Y G+ K P R N
Sbjct: 6081 FVTELEPLEAAVGDSVSLQCQVAGTPEIT-VSW-------YKGDTKLRPTPEYRTYFTNN 6132
Query: 94 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEG 150
T ++ V++ D G YTC + +S+ +Q +PP DI G
Sbjct: 6133 VAT---LVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVG 6189
Query: 151 SSVTLLCLAIGRPEPTVTWRHLSV------KEGQGFVSEDEYLEISDIKRDQSGEYECSA 204
VTL C G V W V FV L+I SG+Y CSA
Sbjct: 6190 LPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSA 6249
Query: 205 LNDVAAPDVRKVKITVNYP---PYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 260
N + ++T P P+ K + V G+ C + W K+
Sbjct: 6250 SNPLGTAS-SSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 6308
Query: 261 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ G I G L V + D G YTC ATN +G S L
Sbjct: 6309 KEIRPG-GNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Score = 69.7 bits (169), Expect = 4e-12
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 34/241 (14%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP---PQIMNISSDITVNEGSSVTLL 156
+ ++ + D G YTC V D ++++ P P + +TV+EG V L
Sbjct: 8307 LQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLS 8366
Query: 157 CLAIGRPEPTVTWRHLSVKEGQ----------GFVSEDEYLEISDIKRDQSGEYECSALN 206
C G + W +K G+ F S LE+ D+ + SG+Y C A N
Sbjct: 8367 CHVQGSEPIRIQW----LKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN 8422
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILS----------------CEASAVP 250
VA D K K+T+ P ++ A G+ +S + P
Sbjct: 8423 -VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481
Query: 251 MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT 310
+ +W K + R + I KG + L + ++ D G Y CVA N+ G +++
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVN 8541
Query: 311 L 311
L
Sbjct: 8542 L 8542
Score = 68.2 bits (165), Expect = 1e-11
Identities = 62/287 (21%), Positives = 111/287 (38%), Gaps = 21/287 (7%)
Query: 36 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 94
A F K +++ ++ +G+ L T V W ++ P + T
Sbjct: 7868 AKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGI---------NVTPSQRCNITT 7918
Query: 95 PTQYSIM-IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 153
+ +I+ I + V D G Y C ++ + + +++ PP + + V+ G S
Sbjct: 7919 TEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSA 7978
Query: 154 TLLCLAIGRPEPTVTWRHLSVK------EGQGFVSEDEYLEISDIKRDQSGEYECSALN- 206
+L C G PE V+W K F + L + + + SGEY C A N
Sbjct: 7979 SLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENS 8038
Query: 207 --DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
+V+A V+ P + + ++ +VG + C S W+K+ L
Sbjct: 8039 VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++ +TL F G Y+C ATN +G+ ++S L
Sbjct: 8099 DS-PNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 67.8 bits (164), Expect = 1e-11
Identities = 72/306 (23%), Positives = 119/306 (38%), Gaps = 49/306 (16%)
Query: 45 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
VTV+ G+ A I R +++W +L G ++ +Y++++
Sbjct: 3248 VTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK--------CKFLHDGQEYTLLLI 3299
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV-------------PPQIMNISSDITVNEG 150
D YTC + D T+ L V+V PP I+ D +EG
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEG 3359
Query: 151 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF---VSEDEY-LEISDIKRDQSGEYECSA 204
C G + V+W + +K + F ED Y LEI++ + G Y A
Sbjct: 3360 QPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVA 3418
Query: 205 LNDVA-----------APD-------VRKVKITVNYPPYIS-KAKNTGVSVGQKGILSCE 245
N V AP+ +++++ + P I K + V++G +CE
Sbjct: 3419 SNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478
Query: 246 ASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNT 305
+ P FQWFK + D I + +S+L D G YTC A+N+ G+
Sbjct: 3479 IQSAPNVRFQWFKAGREIYES-DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 306 NASITL 311
+ + TL
Sbjct: 3538 SCTATL 3543
Score = 67.0 bits (162), Expect = 2e-11
Identities = 48/217 (22%), Positives = 85/217 (39%), Gaps = 8/217 (3%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ + N+++ D YTC V L V+ PP + S+V +
Sbjct: 5293 SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAI 5352
Query: 159 AIGRPEPTVTWRHLSVKEGQG------FVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
G P + W V+ G +L + + ++G+Y C NDV +
Sbjct: 5353 LKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDS 5412
Query: 213 VRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ + P ++ K + + V G L C+ + P WF+ E L D R
Sbjct: 5413 CTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPAS-DKYR 5471
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS 308
+ ++ + N+S +D G++ C A N G+T+ S
Sbjct: 5472 MTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 5508
Score = 66.2 bits (160), Expect = 4e-11
Identities = 63/288 (21%), Positives = 113/288 (39%), Gaps = 23/288 (7%)
Query: 36 ATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNT 94
ATF K + + +V G L T V+W+ + L + +++ SI T
Sbjct: 6927 ATFVKRLADFSVETGSPIVLEATYTGTPPISVSWI-KDEYLISQSERCSI---------T 6976
Query: 95 PTQYSIMIQNVD--VYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSS 152
T+ S +++ ++ + D Y+C ++ + + V PP + + G
Sbjct: 6977 MTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEP 7036
Query: 153 VTLLCLAIGRPEPTVTW--RHLSVKEGQG----FVSEDEYLEISDIKRDQSGEYECSALN 206
TL C G PE ++W H ++ F + L I+ + GEY C A N
Sbjct: 7037 ATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADN 7096
Query: 207 DVAAPDVRKVKITV--NYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 263
V A V + PP+ + K K+ ++G C + + W+K+ L
Sbjct: 7097 SVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLL 7156
Query: 264 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ ++ ++TL + G Y C A+N LG ++S L
Sbjct: 7157 KDDAN-LQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203
Score = 66.2 bits (160), Expect = 4e-11
Identities = 57/226 (25%), Positives = 94/226 (41%), Gaps = 17/226 (7%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV---QVPP--QIMNISSDITVNEGSSV 153
++ I D G Y CS +S LI+ +VPP + +S D+ + G S
Sbjct: 7172 TLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLAL--GESG 7229
Query: 154 TLLCLAIGRPEPTVTWR--HLSVKEGQGF----VSEDEYLEISDIKRDQSGEYECSALND 207
T C G +TW + ++ G + V L + + + +G+Y C A N
Sbjct: 7230 TFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASN- 7288
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGIL--SCEASAVPMAEFQWFKEETRLAT 265
+A D ++ V PP K V Q C+ P + W+K+ET +
Sbjct: 7289 IAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQE 7348
Query: 266 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
R+ ++ L N+S +D G+YTC A N G+ ++S +L
Sbjct: 7349 S-SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL 7393
Score = 66.2 bits (160), Expect = 4e-11
Identities = 70/283 (24%), Positives = 115/283 (40%), Gaps = 32/283 (11%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGND-KWSIDPRVIILVNTPT 96
F + +++ TV + + A C + V W + G K+ D +
Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSI-------- 12876
Query: 97 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ-VPPQIMNISSDITVNEGSSVTL 155
+ ++I++ + DE Y C V+ + SR L V+ +P +I+ DI G+ V
Sbjct: 12877 -HRLIIKDCRLDDECEYACGVED----RKSRARLFVEEIPVEIIRPPQDILEAPGADVVF 12931
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQG----FVSEDEY--LEISDIKRDQSGEYECSALNDVA 209
L + + + V W ++ QG +SE + L+I DIK GEY A + A
Sbjct: 12932 LA-ELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEA 12990
Query: 210 APDVRKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
+ K+ + P I A ++ V VG+ + A P AE +WFKE L+T
Sbjct: 12991 -----RAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST--- 13042
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
I+ ++ + D G Y V NK G I L
Sbjct: 13043 -KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINL 13084
Score = 64.3 bits (155), Expect = 2e-10
Identities = 69/285 (24%), Positives = 111/285 (38%), Gaps = 29/285 (10%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPT 96
F K + NV + L C I + RV+W + A +D++ R+ + T
Sbjct: 4115 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEI-AASDRY----RIAFVEGTA- 4168
Query: 97 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLL 156
S+ I VD+ D G +TC K S LIVQ PP + V GS+V L
Sbjct: 4169 --SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226
Query: 157 CLAIGRPEPTVTW---RHLSVKEGQGFVSE---DEYLEISDIKRDQSGEYECSALNDVAA 210
G T+ W V G ++++ + LE+ +K SG Y C N
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286
Query: 211 PDVRKVKITVNYPPYISKAKNTG-VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ ++ K + + + G L+C+ + P + WF + +
Sbjct: 4287 VECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI------ 4340
Query: 270 MRIENKGRMS------TLTFFNVSEKDYGNYTCVATNKLGNTNAS 308
+ +K RMS L +V +D G Y C A N+ G+ + S
Sbjct: 4341 -KESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS 4384
Score = 63.9 bits (154), Expect = 2e-10
Identities = 68/287 (23%), Positives = 114/287 (39%), Gaps = 37/287 (12%)
Query: 44 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
+V V + + TL C + +V WL + K + R + S I
Sbjct: 5149 SVDVTEKDPMTLECVVAGTPELKVKWLK--------DGKQIVPSRYFSMSFENNVASFRI 5200
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIV---QVPPQIMNISSDITVNEGSSVTLLCLA 159
Q+V D G YT V+ D + +L V +PP + + GSS+ + C
Sbjct: 5201 QSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKV 5260
Query: 160 IGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSALNDVA 209
G + W K+G+ + +Y LE+++++ + + Y C N VA
Sbjct: 5261 SGSLPISAQW----FKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSN-VA 5315
Query: 210 APDVRKVKITVNYPP--YISKAKNTGV---SVGQKGILSCEASAVPMAEFQWFKEETRLA 264
D +TV PP + + + +V K IL P + +WFK++ L
Sbjct: 5316 GDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILK----GTPPFKIKWFKDDVELV 5371
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+G I +G S L ++V G YTC TN +G+ + + L
Sbjct: 5372 SGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTML 5417
Score = 63.5 bits (153), Expect = 3e-10
Identities = 57/219 (26%), Positives = 80/219 (36%), Gaps = 12/219 (5%)
Query: 102 IQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIG 161
I ++ D G YTCS HL V+ PP + VN + V L L G
Sbjct: 4734 ISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGG 4793
Query: 162 RPEPTVTW----RHLSVKEGQGFVSED--EYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
T+ W + L + +D LE+ K SG Y C NDV K
Sbjct: 4794 TAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTA-TSK 4852
Query: 216 VKITVNYPPYISKAKNTGVSV---GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 272
+ V PP K K + V V GQ C+ + P W+ + + T + I
Sbjct: 4853 ATLFVKEPPQFIK-KPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEI-TAIQKHGI 4910
Query: 273 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++T ++ G Y C A N G + SI L
Sbjct: 4911 SFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIEL 4949
Score = 63.2 bits (152), Expect = 3e-10
Identities = 62/279 (22%), Positives = 100/279 (35%), Gaps = 16/279 (5%)
Query: 32 RSGDATFPKAMDNVTVRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVII 90
R+ +F + + N G S L C + VAW + T + +G +
Sbjct: 5796 RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQT------- 5848
Query: 91 LVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
+ ++ + ++D D G YTC R L VQ PP + + V G
Sbjct: 5849 -TFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPG 5907
Query: 151 SSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEY--LEISDIKRDQSGEYECSA 204
+VT + G P V W R L + ED LE+ +I QSGEY C
Sbjct: 5908 KNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVV 5967
Query: 205 LNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
N+ ++ + + V G+ IL + W K+ +
Sbjct: 5968 SNNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNIT 6027
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
T + I + L N +++D G Y+C N+ G
Sbjct: 6028 TS-EKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAG 6065
Score = 62.8 bits (151), Expect = 4e-10
Identities = 64/293 (21%), Positives = 105/293 (35%), Gaps = 36/293 (12%)
Query: 29 VPVRSGDATFPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPR 87
V VR + K + + GESA L C + V +V W N+K +
Sbjct: 3731 VTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFK--------NNKELSESN 3782
Query: 88 VIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITV 147
+ + ++ + I +V V D G Y+C D + ++++ PP + +
Sbjct: 3783 TVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADI 3842
Query: 148 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQS 197
G++ L C G ++W K+ + S +Y LEI
Sbjct: 3843 VRGTNALLQCEVSGTGPFEISW----FKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADV 3898
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWF 257
GEYEC N+V + P ++ K + GQ L W
Sbjct: 3899 GEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 3958
Query: 258 KEETRLATGLDGMRIENKGRMS------TLTFFNVSEKDYGNYTCVATNKLGN 304
K G + +R + K +MS L +V G YTC+A N+ G+
Sbjct: 3959 K-------GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS 4004
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/221 (21%), Positives = 88/221 (39%), Gaps = 8/221 (3%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ I N++ D G Y C + T + + PP+ + SD + G +V L +
Sbjct: 6514 SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAI 6573
Query: 159 AIGRPEPTVTW---RHLSVKEGQG----FVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
G +V W R ++E + F+ L++ + SG+Y C ND
Sbjct: 6574 VEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMR 6633
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ V + I K + V+ G L C + P +WFK+ L+
Sbjct: 6634 ECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSAD-SKHH 6692
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
I ++++L D G Y+ N +G +N +++++
Sbjct: 6693 ITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVH 6733
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/224 (25%), Positives = 94/224 (41%), Gaps = 12/224 (5%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---VPPQIMNISSDITVNEGSSVTL 155
S+ I ++ D+G Y+ V+ V + V VPP + D+ G+SV L
Sbjct: 6701 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 6760
Query: 156 LCLAIGRPEPTVTWRH-----LSVKEGQGFVSEDEY-LEISDIKRDQSGEYECSALNDVA 209
C G +V W +S + Q SE+ L +S ++ +G Y C A N VA
Sbjct: 6761 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAAN-VA 6819
Query: 210 APDVRKVKITVNYPPYISKAKNT-GVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
D +TV PP + ++ V G + P + +WFK L G +
Sbjct: 6820 GSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG-E 6878
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
I + ++ L F V + G+Y+C+ TN G+ + + L+
Sbjct: 6879 SCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 6922
Score = 58.9 bits (141), Expect = 6e-09
Identities = 56/254 (22%), Positives = 92/254 (36%), Gaps = 30/254 (11%)
Query: 81 KWSIDPRVIILVNTPTQYSIMIQN---------VDVYDEGPYTCSVQTD---NHPKTSRV 128
KW D R ++ +Y I +N +++D G YT + + + +T+
Sbjct: 4049 KWYKDGRPLV---ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT 4105
Query: 129 HLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY-- 186
L + P ++ + L C G V+W K+G+ + D Y
Sbjct: 4106 VLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSW----FKDGKEIAASDRYRI 4161
Query: 187 --------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQ 238
LEI + + +G + C A N V + D I P +++K + V G
Sbjct: 4162 AFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGS 4221
Query: 239 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
L +WFK L +G I + S+L + V D G YTC
Sbjct: 4222 AVCLKSTFQGSTPLTIRWFKGNKELVSG-GSCYITKEALESSLELYLVKTSDSGTYTCKV 4280
Query: 299 TNKLGNTNASITLY 312
+N G S L+
Sbjct: 4281 SNVAGGVECSANLF 4294
Score = 58.5 bits (140), Expect = 8e-09
Identities = 60/285 (21%), Positives = 115/285 (40%), Gaps = 19/285 (6%)
Query: 36 ATFPKAMD-NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVN 93
ATF + ++ + +++G++ L C + ++ W + K S R+ + +
Sbjct: 4299 ATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI-----KESSKHRMSFVES 4353
Query: 94 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 153
T + + +V + D G Y C Q + +IV+ P I V + V
Sbjct: 4354 TAV---LRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDV 4410
Query: 154 TLLCLAIGRPEPTVTW--RHLSVKEGQGFVS--EDEYLEISDIK--RDQSGEYECSALND 207
LL G P +TW + ++ G+ + + +D + + +K +GEY+C N+
Sbjct: 4411 MLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE 4470
Query: 208 VAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
V + + ++T+ PP +I K ++T G W K+ + T
Sbjct: 4471 VGS-SICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEI-TE 4528
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
D +R+ + +++L + K G Y C A N G S L
Sbjct: 4529 DDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 4573
Score = 57.4 bits (137), Expect = 2e-08
Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 9/204 (4%)
Query: 116 SVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK 175
S+ + KTS+ V+ +I S+ +++NEG + L G + + +
Sbjct: 33019 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELT 33078
Query: 176 EGQ----GFVSEDEYLEISDIKRDQSGEYECSALNDVAAP----DVRKVKITVNYPPYIS 227
+ G D+ L I G C + D+ K + P +IS
Sbjct: 33079 NSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFIS 33138
Query: 228 KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVS 287
+ ++ ++ GQ + +CE S P E +WFK ++ + I + +L N S
Sbjct: 33139 QPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISIS-SNVSISRSRNVYSLEIRNAS 33197
Query: 288 EKDYGNYTCVATNKLGNTNASITL 311
D G YT A N G +A+ +L
Sbjct: 33198 VSDSGKYTIKAKNFRGQCSATASL 33221
Score = 54.3 bits (129), Expect = 2e-07
Identities = 61/245 (24%), Positives = 91/245 (37%), Gaps = 58/245 (23%)
Query: 124 KTSRVHLIVQVP---PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR------HLSV 174
+T+RV V++P P +++ ++TV EG SVTL C G P PTVTW S+
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 175 KEGQGFVSEDEYLEISDIKRDQSGEYECSALND---VAAPDVRKVKITVNY--------- 222
F S L I + + SG + CSA+N+ V+ V+++ +
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE 1047
Query: 223 ----------------------------------PPYISKAKNTGVSVGQKGILSCEASA 248
P +I+K + G + C+
Sbjct: 1048 KFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGG 1107
Query: 249 VPMAEFQWFKEETRLATGLDGMRIENK--GRMSTLTFFNVSEKDYGNYTCVATNKLGNTN 306
P W K L TG NK G + ++ D G YT V NK G T+
Sbjct: 1108 NPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFAD-DAGEYTIVVRNKHGETS 1166
Query: 307 ASITL 311
AS +L
Sbjct: 1167 ASASL 1171
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/253 (22%), Positives = 92/253 (36%), Gaps = 27/253 (10%)
Query: 66 VAWLNRSTILYAGND-KWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPK 124
+ W +TIL +G K I ++ S+ I D G Y C V +
Sbjct: 4424 ITWFKDNTILRSGRKYKTFIQDHLV---------SLQILKFVAADAGEYQCRVTNEVGSS 4474
Query: 125 TSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSED 184
+ ++ PP + + G + G TVTW +K+ +D
Sbjct: 4475 ICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTW----LKDSDEITEDD 4530
Query: 185 EY----------LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS-KAKNTG 233
L +S I+ G+Y C A ND + ++V P I+ +A +
Sbjct: 4531 NIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSAL-LSVKEPATITEEAVSID 4589
Query: 234 VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGN 293
V+ G L + S +WFK+ L G +I +S L + +KD G
Sbjct: 4590 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLG-SKYKISVTDTVSILKIISTEKKDSGE 4648
Query: 294 YTCVATNKLGNTN 306
YT N +G ++
Sbjct: 4649 YTFEVQNDVGRSS 4661
Score = 53.9 bits (128), Expect = 2e-07
Identities = 69/289 (23%), Positives = 120/289 (41%), Gaps = 36/289 (12%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDDRVT----RVAWLNRSTILYAGNDKWSIDPRVIILV 92
T K ++N TV + A ID ++ +++W Y G +K + I +
Sbjct: 8657 TLIKDIENQTVLKDNDAVFE--IDIKINYPEIKLSW-------YKGTEKLEPSDKFEISI 8707
Query: 93 NTPTQYSIMIQNVDVYDEGPY--TCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
+ ++++ ++N + D+G Y C P + L V P ++ D+T+ EG
Sbjct: 8708 DGD-RHTLRVKNCQLKDQGNYRLVCG------PHIASAKLTVIEPAWERHLQ-DVTLKEG 8759
Query: 151 SSVTLLCLAIGRPEPTVTW-RHLSVKEGQG-FVSEDEY----LEISDIKRDQSGEYECSA 204
+ T+ C P W R+ + + QG +E E+ L I+D++ + G+Y C
Sbjct: 8760 QTCTMTC-QFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKY 8818
Query: 205 LNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
+ + ++R I + + +N VS Q CE S A W+K T L
Sbjct: 8819 EDLETSAELR---IEAEPIQFTKRIQNIVVSEHQSATFECEVS-FDDAIVTWYKGPTEL- 8873
Query: 265 TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA-TNKLGNTNASITLY 312
T N GR +T NV+ D G Y+ +A G ++ LY
Sbjct: 8874 TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELY 8922
Score = 52.8 bits (125), Expect = 5e-07
Identities = 53/231 (22%), Positives = 92/231 (39%), Gaps = 25/231 (10%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G YT + T V+ PPQ++ +TV G + GRP+P ++
Sbjct: 3214 DAGEYTFVAGRNRSSVTLYVN--APEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271
Query: 169 WRHLSVKEGQGFVSE-----DEY-LEISDIKRDQSGEYECSALND-----------VAAP 211
W GF + EY L + + + + Y C A ND V P
Sbjct: 3272 WYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3331
Query: 212 DV--RKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+V ++ V P I+ ++T S GQ C S + + W+ ++ ++
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPS-RF 3389
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG--NTNASITLYGPGAVI 318
R+ L +D G YT VA+N +G ++ A+++L P +++
Sbjct: 3390 FRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3440
Score = 52.8 bits (125), Expect = 5e-07
Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 215 KVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIE 273
K K+T P I K K+ +G+ LSC+ P+ + +W++ L ++
Sbjct: 30524 KTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK-YKMS 30582
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ GR TLT ++D G YTC+ATN++G S L
Sbjct: 30583 SDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKL 30620
Score = 52.0 bits (123), Expect = 8e-07
Identities = 70/274 (25%), Positives = 103/274 (37%), Gaps = 27/274 (9%)
Query: 31 VRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRST-ILYAGNDKWSIDPRVI 89
V+ F K +++ TV +G +A L C + +V W T IL + + D RV
Sbjct: 12280 VKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVR 12339
Query: 90 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE 149
LV I + D YTC + KTS +V + + +D+ V E
Sbjct: 12340 KLV---------IHDCTPEDIKTYTCDAKDF---KTSCNLNVVPPHVEFLRPLTDLQVRE 12387
Query: 150 GSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF--VSED--EYLEISDIKRDQSGEYECS 203
C + R V W +K+G+ + +S+ L I+ D EY C
Sbjct: 12388 KEMARFEC-ELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCE 12446
Query: 204 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFK-EETR 262
A + + + N VS L CE S P AE W+K +E
Sbjct: 12447 VR---TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEI 12502
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 296
+ TG I +GR L N +D GNY C
Sbjct: 12503 IETG--RYEILTEGRKRILVIQNAHLEDAGNYNC 12534
Score = 48.9 bits (115), Expect = 7e-06
Identities = 62/282 (21%), Positives = 112/282 (39%), Gaps = 38/282 (13%)
Query: 35 DATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNT 94
+A F K + N+ V + ++ L C + V W Y G+++ R IL
Sbjct: 12462 EAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIW-------YKGDEEIIETGRYEILTEG 12514
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVT 154
+ ++IQN + D G Y C + + +VH ++ + ++ ++ + EG
Sbjct: 12515 RKRI-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---ELAAEFISKPQNLEILEGEKAE 12570
Query: 155 LLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR----------DQSGEYECSA 204
+C +I + V W+ ++ + S D+Y I+D K+ G Y
Sbjct: 12571 FVC-SISKESFPVQWK----RDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 12625
Query: 205 LNDVAAPD---VRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEET 261
AA + K++I V K+T V Q+ + +CE + A+ +WF+ E
Sbjct: 12626 GAARAAAHLTVIEKLRIVV-------PLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEE 12677
Query: 262 RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ + I K + TL + D NY TN G
Sbjct: 12678 AIFDSSKYI-ILQKDLVYTLRIRDAHLDDQANYNVSLTNHRG 12718
Score = 48.1 bits (113), Expect = 1e-05
Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 33 SGDAT-FPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLN-RSTILYAGNDKWSIDPRVI 89
SG+A K M +VT + GE+A L C I R + + W ++ + K S D R
Sbjct: 30529 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRT- 30587
Query: 90 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI---MNISSDIT 146
+++ + + DEG YTC + + L++Q PQ +
Sbjct: 30588 --------HTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYY 30639
Query: 147 VNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 191
GS++ L + IGRP P +TW H GQ + E + I +
Sbjct: 30640 GAVGSTLRLHVMYIGRPVPAMTWFH-----GQKLLQNSENITIEN 30679
Score = 47.8 bits (112), Expect = 1e-05
Identities = 46/184 (25%), Positives = 73/184 (39%), Gaps = 15/184 (8%)
Query: 136 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEGQGFVSED---EYLEI 189
P I D+T G + L C +GRP P + W ++ + +S D L +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 190 SDIKRDQSGEYECSALNDVAAPDVRKVKITVN-----YPPYISKAKNTGVSVGQKGILSC 244
+++ G Y C A N+V + K+ + +P Y K K G +VG L
Sbjct: 30593 MTEEQEDEGVYTCIATNEVGEVETSS-KLLLQATPQFHPGYPLKEKYYG-AVGSTLRLHV 30650
Query: 245 EASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDY-GNYTCVATNKLG 303
P+ WF + +L + + IEN + L NV K + G Y +N G
Sbjct: 30651 MYIGRPVPAMTWFHGQ-KLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFG 30709
Query: 304 NTNA 307
+A
Sbjct: 30710 TVDA 30713
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/186 (22%), Positives = 73/186 (39%), Gaps = 20/186 (10%)
Query: 145 ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ------------GFVSEDEYLEISDI 192
+ V EGS+ T G P P V+W ++GQ F L I +
Sbjct: 15 VVVLEGSTATFEAHISGFPVPEVSW----FRDGQVISTSTLPGVQISFSDGRAKLTIPAV 70
Query: 193 KRDQSGEYECSALN---DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAV 249
+ SG Y A N + VK P ++ + ++ V G + L + +
Sbjct: 71 TKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P +++++ + + LD +I +G + +L +D G Y+ ATN +G ++
Sbjct: 131 PTPVVKFYRDGAEIQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 310 TLYGPG 315
L G
Sbjct: 190 ELLVQG 195
Score = 46.2 bits (108), Expect = 4e-05
Identities = 71/296 (23%), Positives = 116/296 (39%), Gaps = 45/296 (15%)
Query: 31 VRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSI--DPRV 88
V+ + F + +VTV + A C + R V W I+ + +DK+ I D +
Sbjct: 11481 VKEIELDFAVPLKDVTVPERRQARFECVLT-REANVIWSKGPDIIKS-SDKFDIIADGKK 11538
Query: 89 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN 148
ILV +Q+ DEG YT V+ KTS + + + M+ D TV
Sbjct: 11539 HILVINDSQFD---------DEGVYTAEVEGK---KTSARLFVTGIRLKFMSPLEDQTVK 11586
Query: 149 EGSSVTLLCLAIGRPEPTVTWRHLSVK-----------EGQGFVSEDEYLEISDIKRDQS 197
EG + T +C + + V W K EG+ E + + + DI + ++
Sbjct: 11587 EGETATFVC-ELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA 11645
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASA-VPMAEFQW 256
E S+ ++K+ P + K + + L CE S VP+ +W
Sbjct: 11646 QVKELSS--------TAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV---KW 11694
Query: 257 FKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC-VATNKLGNTNASITL 311
FK+ + I+ G L KD G Y C T+K T A++T+
Sbjct: 11695 FKDGEEIVPS-PKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDK---TKANVTV 11746
Score = 45.4 bits (106), Expect = 7e-05
Identities = 67/286 (23%), Positives = 116/286 (40%), Gaps = 29/286 (10%)
Query: 40 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS 99
+ + +VTV GE+AT C + V W + L + + PR V+T T
Sbjct: 12200 RPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSD---KVVPRSEGKVHTLT--- 12253
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP-QIMNISSDITVNEGSSVTLLCL 158
+++V + D G VQ + +L V+ PP + D TV EG++ L C
Sbjct: 12254 --LRDVKLEDAG----EVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLEC- 12306
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN-DVAAPDVRKVK 217
+ R V W K G + +Y ++D + + ++C+ + D + K
Sbjct: 12307 EVSRENAKVKW----FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK 12362
Query: 218 ITVN---YPPYISKAKN-TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLDGMR 271
+ N PP++ + T + V +K + CE S A+ +WFK+ + G
Sbjct: 12363 TSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSR-ENAKVKWFKDGAEIKKG-KKYD 12420
Query: 272 IENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAV 317
I +KG + L D Y+C + T+ +T+ AV
Sbjct: 12421 IISKGAVRILVINKCLLDDEAEYSCEV--RTARTSGMLTVLEEEAV 12464
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 24/134 (17%)
Query: 195 DQSGEYECSALN----DVAAPDVRKVKITV---NYPPYISKAKNTGVSVGQKGILSCEAS 247
++ +Y+ A+ +++ P +T+ N PP I +SV K +L+ +A
Sbjct: 19257 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRID------LSVAMKSLLTVKAG 19310
Query: 248 A----------VPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCV 297
PM W K+ T L +G+++ + + TL F+V+ KD G+YT
Sbjct: 19311 TNVCLDATVFGKPMPTVSWKKDGTLLKPA-EGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369
Query: 298 ATNKLGNTNASITL 311
A N G+ +A+I L
Sbjct: 19370 AENSSGSKSATIKL 19383
Score = 44.7 bits (104), Expect = 1e-04
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 134 VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSED----E 185
+PP+I + SDI+++EG +T+ C G P P VTW R + +E F E+
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 33386
Query: 186 YLEISDIKRDQSGEYECSALND 207
L I D+++ G Y S N+
Sbjct: 33387 TLIIMDVQKQDGGLYTLSLGNE 33408
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/202 (21%), Positives = 75/202 (37%), Gaps = 25/202 (12%)
Query: 136 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQG-----FVSEDEYLE-- 188
P+I TV +GS +G+P+P W VK + + ED E
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 189 ISDIKRDQSGEYECSALNDVAAPD---------VRKVKITVNYPPYISKAKNTGVSVGQK 239
I D+ + S A+N + + T ++K K+T
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT------M 2191
Query: 240 GILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVAT 299
CE S P + +W+K+ + G D R+ + ++ L+ + D +Y+CV
Sbjct: 2192 ATFECETSE-PFVKVKWYKDGMEVHEG-DKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 300 NKLGNTNASITLYGPGAVIDGV 321
N + L GAV++ V
Sbjct: 2250 ED-ENVKTTAKLIVEGAVVEFV 2270
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/142 (25%), Positives = 62/142 (43%), Gaps = 6/142 (4%)
Query: 173 SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD---VRKVKITVNYPPYISKA 229
SV+E + ++E +S + S E + +AL + + + RK+K T+ ++K
Sbjct: 32510 SVREVKSQMTETRE-SLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLA-ARILTKP 32567
Query: 230 KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK 289
++ V G+ SC+ P+ W ++ L+T K + ST +V
Sbjct: 32568 RSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSVQAS 32626
Query: 290 DYGNYTCVATNKLGNTNASITL 311
D GNY+ V N G A TL
Sbjct: 32627 DEGNYSVVVENSEGKQEAEFTL 32648
Score = 43.1 bits (100), Expect = 4e-04
Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 30/282 (10%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 97
F K + ++ V + S L C + W + L + N K++I R +
Sbjct: 2269 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKS-NGKYTITSR-------RGR 2320
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 157
++ +++V D+G Y+ + D T ++ + + P I+ SD V EG V L
Sbjct: 2321 QNLTVKDVTKEDQGEYSFVI--DGKKTTCKLKMKPR-PIAILQGLSDQKVCEGDIVQLE- 2376
Query: 158 LAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSALND 207
+ + W +K+GQ D L I D+ ++ +G Y +
Sbjct: 2377 VKVSLESVEGVW----MKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTI--- 2429
Query: 208 VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
A +++V I+ K+ V G K +L C+ S + +W+ + ++
Sbjct: 2430 PALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPD- 2488
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
D ++ KG L D G Y + N N S+
Sbjct: 2489 DRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSV 2530
Score = 43.1 bits (100), Expect = 4e-04
Identities = 52/228 (22%), Positives = 78/228 (34%), Gaps = 29/228 (12%)
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEP 165
+VYD Y C + + +++ PP+ + T G +V PEP
Sbjct: 31663 EVYD---YYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEP 31719
Query: 166 TVTWRHLSVKEGQGFVSEDE-------------YLEISDIKRDQSGEYECSALNDVAAPD 212
VTW K GQ D L I+ + D EY A N
Sbjct: 31720 HVTW----YKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDS 31775
Query: 213 VR-KVKITVNYPPYISKAK--------NTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 263
+ K+ +T++ PP S + N GQ S +P +W K+ L
Sbjct: 31776 CKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPL 31835
Query: 264 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ G + I L + +D G Y ATN G+T+ L
Sbjct: 31836 SLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 31883
Score = 41.6 bits (96), Expect = 0.001
Identities = 58/259 (22%), Positives = 98/259 (37%), Gaps = 28/259 (10%)
Query: 50 GESATLRCTIDDRVTRVAWL-NRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVY 108
G SA C + W+ + S I + ++ D + + I +V +
Sbjct: 11133 GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGK---------DRKLHIIDVQLS 11183
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQ--IMNISSDITVNEGSSVTLLCLAIGRPEPT 166
D G YTC ++ N KTS L+V+ P + + ++TV +G + L C E
Sbjct: 11184 DAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCEL--NKERD 11241
Query: 167 VTWRH----LSVKEGQ---GFVSEDEYLEISDIKRDQSGEYEC---SALNDVAAPDVRKV 216
V WR + K G+ G + L I+D +G Y +A N + V+ V
Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301
Query: 217 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENK 275
++ ++ + ++ V I +C+ A +WFK + A D I
Sbjct: 11302 EVIRDW--LVKPIRDQHVKPKGTAIFACDI-AKDTPNIKWFKGYDEIPAEPNDKTEILRD 11358
Query: 276 GRMSTLTFFNVSEKDYGNY 294
G L N +D Y
Sbjct: 11359 GNHLYLKIKNAMPEDIAEY 11377
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 13/124 (10%)
Query: 135 PPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS----VKEGQ-GFVSEDEY 186
PP+I ++ + V G + L + GRP P VTWR + V++GQ V +
Sbjct: 18603 PPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAF 18662
Query: 187 LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEA 246
L I + RD SG+Y + +N V ++ P +S K + V+ SC
Sbjct: 18663 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTK-----TSCHV 18717
Query: 247 SAVP 250
S P
Sbjct: 18718 SWAP 18721
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 16/101 (15%)
Query: 134 VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR----------HLSVKEGQGFVSE 183
+PP+I+ + IT+ G + + G+P PT W+ HL+V +
Sbjct: 18898 LPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK----ADS 18952
Query: 184 DEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
L I D+ R SG Y +A N + D +K+K+ V P
Sbjct: 18953 SSILIIKDVTRKDSGYYSLTAENS-SGTDTQKIKVVVMDAP 18992
Score = 40.8 bits (94), Expect = 0.002
Identities = 55/287 (19%), Positives = 113/287 (39%), Gaps = 33/287 (11%)
Query: 47 VRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
+ +G++ C I + + W + N SI V I + YS+ I+N
Sbjct: 33145 INEGQNVLFTCEISGEPSPEIEW-------FKNNLPISISSNVSIS-RSRNVYSLEIRNA 33196
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHL----IVQVPPQ--IMNISSDITVNEGSSVTLLCLA 159
V D G YT + ++ L +V+ P + ++ S D ++ S + ++
Sbjct: 33197 SVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMS 33256
Query: 160 IGRPEPT-----------VTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 208
+ E + +T + Q S E S ++ S S + +
Sbjct: 33257 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQE----SFVEMSSSSFMGISNMTQL 33312
Query: 209 AAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILS--CEASAVPMAEFQWFKEETRLATG 266
+ + +K + P +A + +S+ + +L+ C + P E W ++ +
Sbjct: 33313 ESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQ 33372
Query: 267 LDG-MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
G IEN ++TL +V ++D G YT N+ G+ +A++ ++
Sbjct: 33373 EQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIH 33419
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/182 (24%), Positives = 71/182 (39%), Gaps = 16/182 (8%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
TF + + +V V +G +AT I V V+W ++ S P V I +
Sbjct: 7 TFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVIST-----STLPGVQISFSDG 61
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV---PPQIMNISSDITVNEGSS 152
+ + I V + G Y+ + TS L+V+ PP + +TV +GS
Sbjct: 62 -RAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ 120
Query: 153 VTLLCLAIGRPEPTVTWRH--LSVKEGQGFVSEDE----YLEISDIKRDQSGEYECSALN 206
V L G P P V + ++ F E L I++ + SG Y +A N
Sbjct: 121 VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN 180
Query: 207 DV 208
V
Sbjct: 181 SV 182
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 27/175 (15%)
Query: 149 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRD------------- 195
EG + +GRP P W H +GQ V++ Y IK D
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFH----DGQQIVND--YTHKVVIKEDGTQSLIIVPATPS 1523
Query: 196 QSGEYECSALNDVAAPDVRKVKITVNY------PPYISKAKNTGVSVGQKGILSCEASAV 249
SGE+ A N + V +TV P ++ K KN + G + + A+
Sbjct: 1524 DSGEWTVVAQNRAGRSSI-SVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGN 1582
Query: 250 PMAEFQWFKEETRLAT-GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
P + W K + +RIE + L + +D YT A NK G
Sbjct: 1583 PNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637
Score = 40.0 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 9/100 (9%)
Query: 116 SVQTDNHPKTSRVHLIVQVPPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRH- 171
++ + P L VPP+I + + S +TV G++V L G+P PTV+W+
Sbjct: 19273 NISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 19332
Query: 172 ---LSVKEGQGFVSEDEY--LEISDIKRDQSGEYECSALN 206
L EG + LE+ + R SG+Y +A N
Sbjct: 19333 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN 19372
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/140 (22%), Positives = 60/140 (42%), Gaps = 16/140 (11%)
Query: 189 ISDIKRDQSGEYECSALNDVAAPD----VRKVKITVNYPPYIS-----KAKNTGVSVGQK 239
+ ++ Q E+ A+N++ + + V PP I + V G+
Sbjct: 15356 VENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEP 15415
Query: 240 GILSCEASAVPMAEFQWFKEETRLATGLDGMRI--ENKGRMSTLTFFNVSE---KDYGNY 294
+ + + +PM + +W K ET + D ++I E R T ++ + +D G Y
Sbjct: 15416 VHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTY 15475
Query: 295 TCVATNKLGNT--NASITLY 312
T A+N+LG+ N + +Y
Sbjct: 15476 TVTASNRLGSVFRNVHVEVY 15495
Score = 38.9 bits (89), Expect = 0.007
Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 15/174 (8%)
Query: 141 ISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEIS 190
+ + + G V +L GRP PTVTWR K+ + S+ Y L I
Sbjct: 27277 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWR----KDEKNLGSDARYSIENTDSSSLLTIP 27332
Query: 191 DIKRDQSGEYECSALNDVAAPDVRKVKITV-NYPPYISKAKNTGVSVGQKGILSCEASAV 249
+ R+ +G+Y + N V P V + V + P K + VS G +L
Sbjct: 27333 QVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLID 27392
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ + E R AT + +K ++ ++SEK + +A N++G
Sbjct: 27393 GGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG 27446
Score = 38.1 bits (87), Expect = 0.012
Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 20/173 (11%)
Query: 37 TFPKAMDNVTVRQGES-ATLRCTIDDRVTRVAWLNRSTILYAGNDKWSI--DPRVIILVN 93
TF + + +V ++ ++ AT C + +V W ++ G DK+ + D +V
Sbjct: 2175 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEG-DKYRMHSDRKV----- 2228
Query: 94 TPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSV 153
+ + I +D D Y+C + D + KT+ ++ + + DI V E S
Sbjct: 2229 ----HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSG 2284
Query: 154 TLLCLAIGRPEPTVTWRHLSVK---EGQGFVSE---DEYLEISDIKRDQSGEY 200
L C+ + W H V+ G+ ++ + L + D+ ++ GEY
Sbjct: 2285 ELECI-VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 38.1 bits (87), Expect = 0.012
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 17/85 (20%)
Query: 135 PPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----- 186
PP++ + ITV G ++ +L GRPEP +TW KEG+ V E
Sbjct: 17905 PPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITW----TKEGKVLVREKRVDLIQD 17960
Query: 187 -----LEISDIKRDQSGEYECSALN 206
L+I + R G+Y SA N
Sbjct: 17961 LPRVELQIKEAVRADHGKYIISAKN 17985
Score = 38.1 bits (87), Expect = 0.012
Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 4/115 (3%)
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWF 257
GE E S +++ P K + + P + + +N V L C+ + P +W+
Sbjct: 30906 GESEWSEISEPITP---KSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWY 30962
Query: 258 KE-ETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++ + +A GL E KG L +V++ D Y ATN+ G+ + + +L
Sbjct: 30963 RQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASL 31017
Score = 38.1 bits (87), Expect = 0.012
Identities = 59/297 (19%), Positives = 106/297 (35%), Gaps = 73/297 (24%)
Query: 37 TFPKAMDNVTVRQGESATLRCTID-DRVTRVAWLNRSTILYAG------NDKWSIDPRVI 89
T P++M TV +GESA C D + V V WL + +L K+ +
Sbjct: 32565 TKPRSM---TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEIS 32621
Query: 90 -ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN 148
+ + YS++++N + E +T ++Q K V PP++ +
Sbjct: 32622 SVQASDEGNYSVVVENSEGKQEAEFTLTIQ-----KARVTEKAVTSPPRVKS-------- 32668
Query: 149 EGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDV 208
PEP V S + +K + + + +
Sbjct: 32669 --------------PEPRVK-------------SPEAVKSPKRVKSPEPSHPKAVSPTET 32701
Query: 209 AAPDVRKVK-ITVNYPPYISKAKNTGVSVGQKGILSC--EASAVPMAEFQWFKEETRLAT 265
KV+ + V+ PP I++ S + L+C E+S + E W+K
Sbjct: 32702 KPTPTEKVQHLPVSAPPKITQFLKAEAS-KEIAKLTCVVESSVLRAKEVTWYK------- 32753
Query: 266 GLDGMRIENKGRMS---------TLTFFNVSEKDYGNYTCVATNKLGNTNASITLYG 313
DG +++ G L N++E D G Y C + + G + ++ G
Sbjct: 32754 --DGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMG 32808
Score = 37.4 bits (85), Expect = 0.020
Identities = 62/284 (21%), Positives = 97/284 (34%), Gaps = 36/284 (12%)
Query: 38 FPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQ 97
F +++ TV++GE+AT C + V W L+ R +++ +
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKLHTS--------RTVLISSEGKT 11627
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 157
+ + ++ V + D V+ + +V ++ P D T E +TL C
Sbjct: 11628 HKLEMKEVTLDDISQIKAQVKELSSTAQLKV---LEADPYFTVKLHDKTAVEKDEITLKC 11684
Query: 158 LAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDIKRDQSGEYECSALND 207
+ + P V W K+G+ V +Y L+I GEY C D
Sbjct: 11685 -EVSKDVP-VKW----FKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTD 11738
Query: 208 --VAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT 265
A V I V P Y V VG+ E S P QW + L
Sbjct: 11739 KTKANVTVEARLIKVEKPLY-----GVEVFVGETAHFEIELSE-PDVHGQWKLKGQPLTA 11792
Query: 266 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
D IE+ G+ L N G + A N N +
Sbjct: 11793 SPDCEIIED-GKKHILILHNCQLGMTGEVSFQAANAKSAANLKV 11835
Score = 36.2 bits (82), Expect = 0.044
Identities = 47/189 (24%), Positives = 74/189 (39%), Gaps = 28/189 (14%)
Query: 131 IVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW----------RHLSVKEGQGF 180
IV+ P+ + + + G S+ + L GRP P VTW ++ + + G
Sbjct: 27957 IVEFGPEYFD---GLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 28013
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVR-KVKITVNYPPYISKAKNTGVSVGQK 239
S L + D RD G Y A N + KVK+ + + T ++ G+K
Sbjct: 28014 TS----LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNIT-GEK 28068
Query: 240 GILSCEA----SAVPMAEFQWFKEET-RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNY 294
L +A P+ + K ET RLA L IE+K + T + + +
Sbjct: 28069 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWAL----IEDKCEAQSYTAIKLINGNEYQF 28124
Query: 295 TCVATNKLG 303
A NK G
Sbjct: 28125 RVSAVNKFG 28133
Score = 36.2 bits (82), Expect = 0.044
Identities = 42/206 (20%), Positives = 64/206 (31%), Gaps = 50/206 (24%)
Query: 51 ESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDE 110
E A L C ++ V R + Y K + + Y + I N+ D+
Sbjct: 32731 EIAKLTCVVESSVLRA----KEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQ 32786
Query: 111 GPYTCSVQTDN-----------------HPKTSRVHLI---------------------- 131
G Y C + + H K S++
Sbjct: 32787 GEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPE 32846
Query: 132 -VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR---HLSVKEGQGFVSEDE-- 185
+ P I+ D TV+ S A G P PT W + G+ +SED+
Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGG 32906
Query: 186 -YLEISDIKRDQSGEYECSALNDVAA 210
+LEI SG Y C+ N +
Sbjct: 32907 FFLEIHKTDTSDSGLYTCTVKNSAGS 32932
Score = 35.8 bits (81), Expect = 0.058
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Query: 227 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD-GMRIENKGRMSTLTFFN 285
S+ KN + G C+ S P+ + W+K+ R+ G M GR S L
Sbjct: 1295 SRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS-LRIPV 1353
Query: 286 VSEKDYGNYTCVATNKLGNTNASITLY 312
V +D G YT A+N GN S LY
Sbjct: 1354 VLPEDEGIYTAFASNIKGNAICSGKLY 1380
Score = 35.4 bits (80), Expect = 0.075
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P+ W KEE L D + I+N G S L + KD+G Y ATN G+ A+
Sbjct: 15132 PVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 15189
Query: 310 TLY---GPGAVID 319
+ PG V+D
Sbjct: 15190 RVEVFDVPGPVLD 15202
Score = 35.0 bits (79), Expect = 0.098
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 133 QVPPQI---MNISSDITVNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVSED--- 184
Q P+I + + + +TV G+ + L G+PEP +TW + +K+ + E+
Sbjct: 13685 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 13744
Query: 185 -EYLEISDIKRDQSGEYECSALN 206
+ I D KR +G Y A+N
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVN 13767
Score = 34.7 bits (78), Expect = 0.13
Identities = 36/141 (25%), Positives = 56/141 (39%), Gaps = 19/141 (13%)
Query: 78 GNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD---NHPKTSRVHLIVQ- 133
G+DKW+ V + T T +IQ +E + S Q + + P+ V +I +
Sbjct: 22091 GSDKWATCATVKVTEATITG---LIQG----EEYSFRVSAQNEKGISDPRQLSVPVIAKD 22143
Query: 134 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSV------KEGQGFVSEDE 185
+PP + + TV G + + IGRP P VTW +V + +
Sbjct: 22144 LVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNS 22203
Query: 186 YLEISDIKRDQSGEYECSALN 206
L I D R+ G Y N
Sbjct: 22204 LLTIKDACREDVGHYVVKLTN 22224
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/158 (21%), Positives = 64/158 (40%), Gaps = 21/158 (13%)
Query: 79 NDKWSIDPRV----IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ- 133
++KWS RV ++ N + + V V ++G + P++ V ++ +
Sbjct: 23174 SEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGR--------SDPRSLAVPIVAKD 23225
Query: 134 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRH--LSVKEGQGFVSEDEY--- 186
+ P + S +V G + + GRP+PT+TW L +K+ D
Sbjct: 23226 LVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 23285
Query: 187 -LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYP 223
L I + +D G+Y + N V +T++ P
Sbjct: 23286 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323
Score = 33.9 bits (76), Expect = 0.22
Identities = 38/181 (20%), Positives = 62/181 (34%), Gaps = 17/181 (9%)
Query: 158 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV-RKV 216
+A G P ++EG+ + + L + E A++ AP++ V
Sbjct: 13635 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDV 13694
Query: 217 KITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKG 276
K+ V G K L + P + W K + L + IEN
Sbjct: 13695 KLLAGLT----------VKAGTKIELPATVTGKPEPKITWTKADMILKQD-KRITIENVP 13743
Query: 277 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY-----GPGAVIDGVNSASRALACL 331
+ ST+T + D G Y A N G A + + GP A D + + +
Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 13803
Query: 332 W 332
W
Sbjct: 13804 W 13804
Score = 33.5 bits (75), Expect = 0.29
Identities = 54/289 (18%), Positives = 94/289 (32%), Gaps = 68/289 (23%)
Query: 90 ILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV-----QVPPQIMNISSD 144
+++ S++I D G +T Q + V L V QV P + +
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKN 1564
Query: 145 ITVNEGSSVTLLCLAIGRPEPTVTW--------RHLSVKEGQGFVSEDEYLEISDIKRDQ 196
+ + EGS + + A G P P + W H K + L+I
Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624
Query: 197 SGEYECSALN------------------------------------DVAAPDVRKVKITV 220
S Y +A+N ++AAP++ + +
Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684
Query: 221 NYPPY--------------ISKAKNTGVSVGQKGILSCEASAVPMAE----FQWFKEETR 262
+ K K T + + + G E P+ + +W +
Sbjct: 1685 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744
Query: 263 LATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L + +R+ N+ +L + +D G TC ATNK G + S TL
Sbjct: 1745 LEAA-NRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATL 1792
Score = 33.5 bits (75), Expect = 0.29
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 6/90 (6%)
Query: 136 PQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW---RHLSVKEGQGFVSED--EYLEIS 190
P I+ + V EG + C G P+P V W L K + V D YL+I
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIV 1900
Query: 191 DIKRDQSGEYECSALNDVAAPDVRKVKITV 220
D K +GE + +A N + KVK+ +
Sbjct: 1901 DCKSYDTGEVKVTAENPEGVIE-HKVKLEI 1929
Score = 33.5 bits (75), Expect = 0.29
Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 23/109 (21%)
Query: 137 QIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF-------VSEDEY--- 186
+I+ +TV EG S C G P PTVTW +++GQ V+ +Y
Sbjct: 32562 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTW----LRKGQVLSTSARHQVTTTKYKST 32617
Query: 187 LEISDIKRDQSGEYECSALNDVAAPD------VRKVKIT---VNYPPYI 226
EIS ++ G Y N + ++K ++T V PP +
Sbjct: 32618 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRV 32666
Score = 33.1 bits (74), Expect = 0.37
Identities = 53/279 (18%), Positives = 103/279 (36%), Gaps = 31/279 (11%)
Query: 40 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS 99
K +VT + + ++ V W ++S + + + R + +
Sbjct: 2799 KKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKV--------HK 2850
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+M+QN+ D G YT V + L V+ I +I V E + + C
Sbjct: 2851 LMLQNISPSDAGEYTAVV----GQLECKAKLFVET-LHITKTMKNIEVPETKTASFECEV 2905
Query: 160 IGRPEPTVTWRH---LSVKEGQGFVSEDE--YLEISDIKRDQSGEYECSALNDVAAPDVR 214
P++ ++ + + E V + + L I + + S EY ND
Sbjct: 2906 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGND------- 2958
Query: 215 KVKITVNYPPYISKAKNTGVSVGQKGILSCEASA-VPMAEFQWFKEETRLATGLDGMRIE 273
+V T+ P + + ++ +K ++ E + ++W K + + D ++
Sbjct: 2959 QVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNGVEIKS-TDKCQMR 3017
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
K +L NV D +YT VA G ++ TLY
Sbjct: 3018 TKKLTHSLNIRNVHFGDAADYTFVA----GKATSTATLY 3052
Score = 33.1 bits (74), Expect = 0.37
Identities = 29/134 (21%), Positives = 50/134 (37%), Gaps = 6/134 (4%)
Query: 181 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN-----YPPYISKAKNTGVS 235
V +D L ++ +K + ++ +A N V R+ + PP I + +
Sbjct: 18852 VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIK 18911
Query: 236 VGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYT 295
G+K + P +W K E + T + + S L +V+ KD G Y+
Sbjct: 18912 AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS-SHLAVHKADSSSILIIKDVTRKDSGYYS 18970
Query: 296 CVATNKLGNTNASI 309
A N G I
Sbjct: 18971 LTAENSSGTDTQKI 18984
Score = 32.7 bits (73), Expect = 0.49
Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 26/135 (19%)
Query: 45 VTVRQGESATLRCTIDDRVTRV-AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI- 102
VT+R G S L ++ R V W K ID +++T YS++I
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITW-----------SKQGIDLASRAIIDTTESYSLLIV 29504
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
V+ YD G YT + + K++ V + V P G ++ + R
Sbjct: 29505 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTP-------------GPCPSVKVKEVSR 29551
Query: 163 PEPTVTWRHLSVKEG 177
T+TW ++ G
Sbjct: 29552 DSVTITWEIPTIDGG 29566
Score = 32.7 bits (73), Expect = 0.49
Identities = 43/205 (20%), Positives = 73/205 (35%), Gaps = 16/205 (7%)
Query: 121 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEG 177
+ P T + + +Q P ++ V S+ TL+C G P+P V W + +G
Sbjct: 30914 SEPITPKSDVPIQAP-HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADG 30972
Query: 178 -----QGFVSEDEYLEISDIKRDQSGEYECSALND------VAAPDVRKVKITVNYPPYI 226
Q F L I+ + D + Y+ A N A+ +V +V ++ P +
Sbjct: 30973 LKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV-EVPAKIHLPKTL 31031
Query: 227 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 286
G+ + S P W K + + I + S + V
Sbjct: 31032 EGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGV 31091
Query: 287 SEKDYGNYTCVATNKLGNTNASITL 311
KD G Y A N+ G ++ L
Sbjct: 31092 ERKDAGFYVVCAKNRFGIDQKTVEL 31116
Score = 32.3 bits (72), Expect = 0.64
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 12/125 (9%)
Query: 189 ISDIKRDQSGEYECSALNDVAA--PDVRKVKITVN---YPP--YISKAKNTGVSVGQKGI 241
+ +K + EY SA+N V P IT PP ++ + VG+
Sbjct: 16778 VKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFA 16837
Query: 242 LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK--DYGNYTCVAT 299
L+ S P + WFK+E A L+ R K +TL + K D G Y V
Sbjct: 16838 LTGRYSGKPKPKVSWFKDE---ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVE 16894
Query: 300 NKLGN 304
N G+
Sbjct: 16895 NSTGS 16899
Score = 32.3 bits (72), Expect = 0.64
Identities = 28/132 (21%), Positives = 54/132 (40%), Gaps = 12/132 (9%)
Query: 189 ISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEAS 247
++D++ + ++ SA+N D +V T+ ++ + + + Q ++ AS
Sbjct: 28315 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGAS 28374
Query: 248 AVPMAEFQ--------WFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVAT 299
+Q W K ++ L+ D I STLT N + D G YT
Sbjct: 28375 IRLFIAYQGRPTPTAVWSKPDSNLSLRAD---IHTTDSFSTLTVENCNRNDAGKYTLTVE 28431
Query: 300 NKLGNTNASITL 311
N G+ + + T+
Sbjct: 28432 NNSGSKSITFTV 28443
Score = 32.3 bits (72), Expect = 0.64
Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 4/71 (5%)
Query: 140 NISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRD 195
++ +T+ G+S+ L+ GRP P +TW + + + L + + R
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRY 29510
Query: 196 QSGEYECSALN 206
+G+Y A N
Sbjct: 29511 DAGKYTIEAEN 29521
Score = 32.0 bits (71), Expect = 0.83
Identities = 47/217 (21%), Positives = 85/217 (39%), Gaps = 18/217 (8%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLC 157
+ + I D D G YTC+V+ +S L ++ + ++ + S +T
Sbjct: 32907 FFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD--TEAQKVSTQKTSEITPQK 32964
Query: 158 LAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK-- 215
A+ + E ++ + L +E + +SE + E +K + S + AA + K
Sbjct: 32965 KAVVQEE--ISQKALRSEEIK--MSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI 33020
Query: 216 VKITVNYPPYIS---------KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
V + S KA +T +S+ + L +A+ + +W L T
Sbjct: 33021 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVEL-TN 33079
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ R G TLT S +D G TC++ K G
Sbjct: 33080 SEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG 33116
Score = 31.6 bits (70), Expect = 1.1
Identities = 19/89 (21%), Positives = 35/89 (39%)
Query: 223 PPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLT 282
P ++ K + GQ + PM E WF + ++ + + +L
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 283 FFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ D G +T VA N+ G ++ S+ L
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVIL 1545
Score = 31.6 bits (70), Expect = 1.1
Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 145 ITVNEGSSVTLLCLAIGRPEPTVTWRH----LSVKEGQGF--VSEDEYLEISDIKRDQSG 198
+ G ++ + +GRP+PTVTW+ L + F + L I++ R SG
Sbjct: 21075 VIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSG 21134
Query: 199 EYECSALNDV 208
Y +A N V
Sbjct: 21135 PYPLTARNIV 21144
Score = 31.2 bits (69), Expect = 1.4
Identities = 35/155 (22%), Positives = 60/155 (38%), Gaps = 23/155 (14%)
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLIV--------QVPPQIMNISSDITVNEGSSVTLLC 157
D+ + G Y V+ N S+ V +PP I ++ + V EG++V ++
Sbjct: 16080 DLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSI-DLKEFMEVEEGTNVNIVA 16138
Query: 158 LAIGRPEPTVTWRHLSVKEGQG-------------FVSEDEYLEISDIKRDQSGEYECSA 204
G P PT+TW K+ V + L I +R +G Y +A
Sbjct: 16139 KIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITA 16198
Query: 205 LNDV-AAPDVRKVKITVNYPPYISKAKNTGVSVGQ 238
+N++ A ++ + P + K VS Q
Sbjct: 16199 VNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ 16233
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 4/78 (5%)
Query: 140 NISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRD 195
N V G+S+ L GRP PT W +LS++ L + + R+
Sbjct: 28362 NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421
Query: 196 QSGEYECSALNDVAAPDV 213
+G+Y + N+ + +
Sbjct: 28422 DAGKYTLTVENNSGSKSI 28439
Score = 30.8 bits (68), Expect = 1.9
Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 2/94 (2%)
Query: 219 TVNYPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGR 277
T+++ P I+ + ++ V GQ + P AE +W+ L + N
Sbjct: 32369 TLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQES-SKIHYTNTSG 32427
Query: 278 MSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ TL + D G Y V TN G + TL
Sbjct: 32428 VLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 32461
Score = 30.4 bits (67), Expect = 2.4
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 237 GQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 296
G+K + AVP+ W K+ + D + ++N + L D G YT
Sbjct: 14401 GEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRLTMKNDHISAHLEVPKSVRADAGIYTI 14459
Query: 297 VATNKLGNTNASITL 311
NKLG+ ASI +
Sbjct: 14460 TLENKLGSATASINV 14474
Score = 30.4 bits (67), Expect = 2.4
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 14/71 (19%)
Query: 150 GSSVTLLCLAIGRPEPTVTWR-----HLSVKEGQGFVSEDEYLE---------ISDIKRD 195
GS + + + GRP P +W ++K+G + ED LE I + KR
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 196 QSGEYECSALN 206
+G+Y +A N
Sbjct: 15885 HTGKYSITAKN 15895
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 140 NISSDITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRD 195
++ I V+ G + ++ G+P PTVTW R L + + + I + +R
Sbjct: 16529 SVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRS 16588
Query: 196 QSGEYECSALND 207
G Y A N+
Sbjct: 16589 HQGVYSLLAKNE 16600
Score = 30.0 bits (66), Expect = 3.2
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 45 VTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
+ +R G S L I R T V W G I II V T + S+++
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKW---------GKVDGEIRDAAIIDV-TSSFTSLVLD 23001
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHL-IVQVPPQIMNISSDITVNEGSSVT 154
NV+ YD G YT +++ + K++ V + ++ P +N+ + S+T
Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 23053
Score = 30.0 bits (66), Expect = 3.2
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 27/145 (18%)
Query: 78 GNDKWSI--DPRVIILVNTPTQYSIMIQ-NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ- 133
G +KWSI + +V V T Q V Y+E + + P+ V +I +
Sbjct: 24255 GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNE-------KGKSDPRVLGVPVIAKD 24307
Query: 134 --VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF----------V 181
+ P + + ++ G + + IGRP P ++W VK+G+
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISW----VKDGEPLKQTTRVNVEET 24363
Query: 182 SEDEYLEISDIKRDQSGEYECSALN 206
+ L I + +D G+Y +A N
Sbjct: 24364 ATSTVLHIKEGNKDDFGKYTVTATN 24388
Score = 29.6 bits (65), Expect = 4.1
Identities = 24/129 (18%), Positives = 47/129 (36%), Gaps = 7/129 (5%)
Query: 189 ISDIKRDQSGEYECSALNDVAAPDVRKVKITV-----NYPPYISKAKNT-GVSVGQKGIL 242
++ + Q ++ A N+ D R + + V P + NT + G+ +
Sbjct: 24272 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKI 24331
Query: 243 SCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 302
P W K+ L + +E + L ++ D+G YT ATN
Sbjct: 24332 EIPVIGRPRPNISWVKDGEPLKQ-TTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSA 24390
Query: 303 GNTNASITL 311
G ++++
Sbjct: 24391 GTATENLSV 24399
Score = 29.6 bits (65), Expect = 4.1
Identities = 30/125 (24%), Positives = 47/125 (37%), Gaps = 16/125 (12%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP---------QIMNISSDITVN 148
Y + I +V D+ YT + + + L V + P + ++
Sbjct: 31748 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQ 31807
Query: 149 EGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSE--DEY-LEISDIKRDQSGEYE 201
EG SV G P PT+ W + LS+ + E D Y L I D + +G Y
Sbjct: 31808 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 31867
Query: 202 CSALN 206
+A N
Sbjct: 31868 VTATN 31872
Score = 29.3 bits (64), Expect = 5.4
Identities = 30/131 (22%), Positives = 52/131 (39%), Gaps = 12/131 (9%)
Query: 188 EISDIKRDQSGEYECSALNDVA------APDVRKVKITVNYPPYI---SKAKNTGVSVGQ 238
+++ ++ Q+ ++ A+N P+ VK + P I + A+ + VG
Sbjct: 17175 KVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGD 17234
Query: 239 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
LS VP + W KE+ T RI+ S L N + +D G Y+
Sbjct: 17235 TLRLSAIIKGVPFPKVTWKKEDRDAPT---KARIDVTPVGSKLEIRNAAHEDGGIYSLTV 17291
Query: 299 TNKLGNTNASI 309
N G+ S+
Sbjct: 17292 ENPAGSKTVSV 17302
Score = 29.3 bits (64), Expect = 5.4
Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 3/130 (2%)
Query: 183 EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT-GVSVGQKGI 241
ED+ E I R+ +G + S +D + + +I K K+ V G+ +
Sbjct: 24669 EDQRYEFRVIARNAAGNF--SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFV 24726
Query: 242 LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNK 301
L + P+ + W K+ L M I++ + +TL + D G Y +N
Sbjct: 24727 LEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNV 24786
Query: 302 LGNTNASITL 311
G + IT+
Sbjct: 24787 GGTKSIPITV 24796
Score = 29.3 bits (64), Expect = 5.4
Identities = 33/147 (22%), Positives = 56/147 (38%), Gaps = 31/147 (21%)
Query: 183 EDEYLEISDIKRDQSGEYECSALNDVAAPDVRK---------VKITVNYPPYISKAKNTG 233
++ Y E++++ DQ E+ A N AA V + VK V P + K
Sbjct: 25740 QETYFEVTELTEDQRYEFRVFARN--AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797
Query: 234 VSVGQKG---ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM--------STLT 282
V V + G ++ + + P+ W K DG+ IE + R + LT
Sbjct: 25798 VIVVKAGEVLKINADIAGRPLPVISWAK---------DGIEIEERARTEIISTDNHTLLT 25848
Query: 283 FFNVSEKDYGNYTCVATNKLGNTNASI 309
+ +D G Y N G + ++
Sbjct: 25849 VKDCIRRDTGQYVLTLKNVAGTRSVAV 25875
Score = 28.9 bits (63), Expect = 7.0
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P E +W K + + D I+ ++L NV+ D G YT N G +A +
Sbjct: 22970 PTPEVKWGKVDGEIR---DAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFV 23026
Query: 310 TL 311
T+
Sbjct: 23027 TV 23028
Score = 28.9 bits (63), Expect = 7.0
Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 6/85 (7%)
Query: 145 ITVNEGSSVTLLCLAIGRPEPTVTWR--HLSVKEGQGF----VSEDEYLEISDIKRDQSG 198
IT GS T+ GRP P VTW+ + +KE + L + D R SG
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716
Query: 199 EYECSALNDVAAPDVRKVKITVNYP 223
Y + N + + P
Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIGRP 28741
Score = 28.5 bits (62), Expect = 9.2
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 8/88 (9%)
Query: 143 SDITVNEGSSVTLLCLAIGRPEPTVTWRH--LSVKEGQGFV--SEDE---YLEISDIKRD 195
+ +TV G +V L G+P+P+++W L +KE + FV S+ E L I + K++
Sbjct: 27571 AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE-FVRFSKTENKITLSIKNAKKE 27629
Query: 196 QSGEYECSALNDVAAPDVRKVKITVNYP 223
G+Y N V V IT+ P
Sbjct: 27630 HGGKYTVILDNAVCRIAVPITVITLGPP 27657
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 95.9 bits (237), Expect = 5e-20
Identities = 63/216 (29%), Positives = 95/216 (43%), Gaps = 15/216 (6%)
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
T + +QN+ D G +TC + + ++IVQ PPQ D V E +V
Sbjct: 379 TSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEW 438
Query: 156 LCLAIGRPEPTVTWRHLSVK---EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
LC A G P P + W + EGQ V L I + G+YEC A++ +
Sbjct: 439 LCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG--- 495
Query: 213 VRKVKITVNYPP-----YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
V+KV + + P + ++T V VG+ +SC A P W KE ++ T
Sbjct: 496 VKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQI-TES 554
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
++++G TLT ++ D G Y CVA N G
Sbjct: 555 GKFHVDDEG---TLTIYDAGFPDQGRYECVARNSFG 587
Score = 63.2 bits (152), Expect = 3e-10
Identities = 73/290 (25%), Positives = 109/290 (37%), Gaps = 23/290 (7%)
Query: 40 KAMDNVTVRQGESATLRCTIDDRVTRVAWLNRS--TILYAGNDK----W-----SIDPRV 88
+A+ +VTV + + R T + + V N T GN K W S+D
Sbjct: 219 RAVASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLED 278
Query: 89 IILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD-NHPKTSRVHL---IVQVPPQIMNISSD 144
+N ++MI+N D+G Y C + KT L + P + D
Sbjct: 279 DTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQD 338
Query: 145 ITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKE--GQGFVSEDEYLEISDIKRDQSGEYEC 202
V G+S TL C+A G P P +TW + E G V+ L + +I + G + C
Sbjct: 339 TEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTC 398
Query: 203 SALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEET 261
A N I V PP + V + + + CEA P W K
Sbjct: 399 HANNSHGTVQA-AANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGG 457
Query: 262 RLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+L ++G TL ++ D G Y C A + LG S+ L
Sbjct: 458 QLP--VEGQHTVLSS--GTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQL 503
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 95.5 bits (236), Expect = 6e-20
Identities = 76/272 (27%), Positives = 113/272 (41%), Gaps = 25/272 (9%)
Query: 50 GESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVY 108
G S C + DR T++ W L G+ S+ V+ IQN+D
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEGGQLPPGH---SVQDGVL-----------RIQNLDQS 3459
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM-NISSDI-TVNEGSSVTLLCLAIGRPEPT 166
+G Y C + L++Q P ++ NI + + TV G +V CLA+G P+P
Sbjct: 3460 CQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQ 3519
Query: 167 VTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYI 226
VTW + G V + I+ ++ +G+Y C+A N A V + V P I
Sbjct: 3520 VTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATN-AAGTTQSHVLLLVQALPQI 3578
Query: 227 SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 286
S + V G + C AS P + W K + L R+EN + L +V
Sbjct: 3579 SMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLP---PDSRLEN----NMLMLPSV 3631
Query: 287 SEKDYGNYTCVATNKLGNTNASITLYGPGAVI 318
+D G Y C ATN+ G A L P V+
Sbjct: 3632 RPQDAGTYVCTATNRQGKVKAFAHLQVPERVV 3663
Score = 83.2 bits (204), Expect = 3e-16
Identities = 62/224 (27%), Positives = 94/224 (41%), Gaps = 17/224 (7%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQV------PPQIMNISSDITVNEGSSV 153
+ I + D G Y C Q +V +IV PQ+ +++TV G +
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTA 3229
Query: 154 TLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
TL C A G P PT+ W L E + L I + + SG+Y C+A + +
Sbjct: 3230 TLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEA 3289
Query: 214 RKVKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 272
+ + V PPY + ++ V G+ L C A P FQW +R+ + L G
Sbjct: 3290 -TIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQW----SRVGSSLPG--- 3341
Query: 273 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTN--ASITLYGP 314
R L F + +D G Y C TNK+G+ A + + GP
Sbjct: 3342 RATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGP 3385
Score = 79.7 bits (195), Expect = 3e-15
Identities = 71/283 (25%), Positives = 114/283 (40%), Gaps = 36/283 (12%)
Query: 46 TVRQGESATLRCTIDDRVTRVA--WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
TV+QG+ A+ +C I D ++ W R+ L D I P I+ T+ S
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLEWKTRNQEL---EDNVHISPNGSIITIVGTRPS---- 3084
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI-SSDITVNEGSSVTLLCLAIGR 162
+ G Y C S V+L V PP + + + V G +VTL C++ G
Sbjct: 3085 -----NHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGE 3139
Query: 163 PEPTVTWRHLSVKEGQ------GFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKV 216
P + W +S + G + L+IS K +G Y C A N + ++V
Sbjct: 3140 PRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQ-KQV 3198
Query: 217 KITVN-------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
++ V+ P ++ V G L C A+ P W K + L
Sbjct: 3199 EVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPW---- 3254
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLY 312
+++ TL V+++D G Y C AT+ G+ A+I L+
Sbjct: 3255 ---QHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILH 3294
Score = 62.8 bits (151), Expect = 4e-10
Identities = 71/321 (22%), Positives = 111/321 (34%), Gaps = 37/321 (11%)
Query: 6 YLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTR 65
Y+ L L ++ +V TG + G +TV G +ATLRC+
Sbjct: 3183 YVCLAQNALGTAQKQVEVIVDTGA-MAPGAPQVQAEEAELTVEAGHTATLRCS------- 3234
Query: 66 VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKT 125
+T A WS + + +++I V D G Y C+ +
Sbjct: 3235 ------ATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE 3288
Query: 126 SRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDE 185
+ + L V+ PP + +V G +V L CLA G P T W + + +E
Sbjct: 3289 ATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNE 3348
Query: 186 YLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGV----------- 234
L + SG Y C N V + + ++ V PP A +
Sbjct: 3349 LLHFERAAPEDSGRYRCRVTNKVGSAEA-FAQLLVQGPPGSLPATSIPAGSTPTVQVTPQ 3407
Query: 235 ----SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKD 290
S+G C + + +WFKE +L G + + L N+ +
Sbjct: 3408 LETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPG-------HSVQDGVLRIQNLDQSC 3460
Query: 291 YGNYTCVATNKLGNTNASITL 311
G Y C A G AS L
Sbjct: 3461 QGTYICQAHGPWGKAQASAQL 3481
Score = 60.5 bits (145), Expect = 2e-09
Identities = 71/301 (23%), Positives = 111/301 (36%), Gaps = 49/301 (16%)
Query: 46 TVRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 104
+V +G++ L C + +V W R S+ P + + + +
Sbjct: 2061 SVTEGQTLDLNCVVAGSAHAQVTWYRRGG---------SLPPHTQVHGSR-----LRLPQ 2106
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIV-----------QVPPQIMNIS---SDITVNEG 150
V D G Y C V+ + PK + + + V VP I S V EG
Sbjct: 2107 VSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEG 2166
Query: 151 SSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA 210
++ L C+ G+ VTW + L + + SGEY C + +
Sbjct: 2167 QTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVG-TSG 2225
Query: 211 PDVRKVKITVN-------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 263
P V +T+ PP ++ ++ V+ GQ LSC + A+ W+K L
Sbjct: 2226 PLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSL 2285
Query: 264 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNS 323
++ R S L F S D G Y C A+N + ASIT+ G G N
Sbjct: 2286 PA-------RHQVRGSRLYIFQASPADAGQYVCRASNGM---EASITVTVTGT--QGANL 2333
Query: 324 A 324
A
Sbjct: 2334 A 2334
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/229 (24%), Positives = 88/229 (38%), Gaps = 26/229 (11%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ---------VPPQIMNISSDITVNEG 150
+ I V D G Y C V + + + + +Q V P I SS TV EG
Sbjct: 2585 LRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEG 2644
Query: 151 SSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAA 210
++ L C+ +P+ +TW + +L + + SGEY C A N++ A
Sbjct: 2645 QTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDA 2704
Query: 211 PD---VRKVKITVNYP-------PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE 260
+ V V + P P ++ ++ V+ G+ L+C A+ W K
Sbjct: 2705 LEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRG 2764
Query: 261 TRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
L + ++ R S L +VS D G Y C G AS+
Sbjct: 2765 GSLPS-------HHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASV 2806
Score = 55.8 bits (133), Expect = 5e-08
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 52/317 (16%)
Query: 21 LLFLVPTG-VPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWLNRSTILYAG 78
L+ + P G VP T + V +G++ L C + + +V W R L A
Sbjct: 2421 LVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPAR 2480
Query: 79 NDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQ----- 133
+ R+ +L TP D G Y C V + + + V + +Q
Sbjct: 2481 HQVHG--SRLRLLQVTPA------------DSGEYVCRVVGSSGTQEASVLVTIQQRLSG 2526
Query: 134 -----VPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY-- 186
V + SS ++ G ++ L CL + T+TW K G S +
Sbjct: 2527 SHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITW----YKRGGSLPSRHQIVG 2582
Query: 187 --LEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN----------YPPYISKAKNTGV 234
L I + SGEY C N + + + +T+ PP ++ + V
Sbjct: 2583 SRLRIPQVTPADSGEYVCHVSNGAGSRETSLI-VTIQGSGSSHVPSVSPPIRIESSSPTV 2641
Query: 235 SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNY 294
GQ L+C + P A W+K L + R + G S L +S D G Y
Sbjct: 2642 VEGQTLDLNCVVARQPQAIITWYKRGGSLPS-----RHQTHG--SHLRLHQMSVADSGEY 2694
Query: 295 TCVATNKLGNTNASITL 311
C A N + ASI +
Sbjct: 2695 VCRANNNIDALEASIVI 2711
Score = 54.7 bits (130), Expect = 1e-07
Identities = 71/296 (23%), Positives = 113/296 (38%), Gaps = 47/296 (15%)
Query: 45 VTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQN 104
+TV+ G+ A RC+ T T+ + G + + I + +
Sbjct: 1875 LTVQPGQLAEFRCSATGSPT-------PTLEWTGGPGGQLPAKAQIHGGI-----LRLPA 1922
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP--PQIMNISSDITVNEGSSVTLLCLAIGR 162
V+ D+ Y C + + +R L V P++ V+ G +V L C A G
Sbjct: 1923 VEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGV 1982
Query: 163 PEPTVTWRHLSVKEGQGFV-------SEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
P T+TWR KEG ++ L I I +G Y C A + R
Sbjct: 1983 PSATITWR----KEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQAR- 2037
Query: 216 VKITV------NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLA--TGL 267
+++ V + PP ++ + V+ GQ L+C + A+ W++ L T +
Sbjct: 2038 IQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQV 2097
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGVNS 323
G R L VS D G Y C N G ASIT+ +V+ G +S
Sbjct: 2098 HGSR---------LRLPQVSPADSGEYVCRVENGSGPKEASITV----SVLHGTHS 2140
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/223 (25%), Positives = 84/223 (37%), Gaps = 22/223 (9%)
Query: 100 IMIQNVDVYDEGPYTCS----VQTDNHPKTSRVHLIVQVPPQIMNI-SSDITVNEGSSVT 154
+ I+NV + D G Y C+ D T V + +++I +TV G
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAE 1884
Query: 155 LLCLAIGRPEPTVTWR-----HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVA 209
C A G P PT+ W L K L + ++ +Y C A + A
Sbjct: 1885 FRCSATGSPTPTLEWTGGPGGQLPAKA----QIHGGILRLPAVEPTDQAQYLCRA-HSSA 1939
Query: 210 APDVRKVKITVN---YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATG 266
V + + V+ P + T V G+ L C A+ VP A W KE L
Sbjct: 1940 GQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQ 1999
Query: 267 LDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
R + ++TL ++ D G Y CVAT+ G A I
Sbjct: 2000 ARSERTD----IATLLIPAITTADAGFYLCVATSPAGTAQARI 2038
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/242 (22%), Positives = 87/242 (35%), Gaps = 28/242 (11%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIV-----QVPPQIMNISSDITVNEGSSV 153
+++I + D G Y C + +R+ ++V PP + SS +V EG ++
Sbjct: 2009 TLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068
Query: 154 TLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
L C+ G VTW L + + SGEY C N + P
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENG-SGPKE 2127
Query: 214 RKVKITV--------NYPPYISKAK-------NTGVSVGQKGILSCEASAVPMAEFQWFK 258
+ ++V +Y P + ++ V+ GQ L+C A+ W K
Sbjct: 2128 ASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK 2187
Query: 259 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVI 318
L R + G S L V+ D G Y C G AS+ + +VI
Sbjct: 2188 RGGSLPA-----RHQTHG--SLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVI 2240
Query: 319 DG 320
G
Sbjct: 2241 PG 2242
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/271 (23%), Positives = 99/271 (36%), Gaps = 47/271 (17%)
Query: 47 VRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIM-IQN 104
V +G++ L C + + +V W R L A + T S++ +
Sbjct: 2163 VAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQ---------------THGSLLRLHQ 2207
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP------PQIMNISSDITVNEGSSVTLLCL 158
V D G Y C V + P + V + ++ P + SS TV EG ++ L C+
Sbjct: 2208 VTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCV 2267
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPDVR 214
G+ VTW K G + + L I +G+Y C A N + A
Sbjct: 2268 VAGQAHAQVTW----YKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITV 2323
Query: 215 KVKIT----VNYP-----PYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT 265
V T + YP P + ++ V+ GQ L+C A+ W K L
Sbjct: 2324 TVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLP- 2382
Query: 266 GLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 296
+ ++ S L + S D G Y C
Sbjct: 2383 ------VRHQTHGSLLRLYQASPADSGEYVC 2407
Score = 49.7 bits (117), Expect = 4e-06
Identities = 70/297 (23%), Positives = 106/297 (35%), Gaps = 53/297 (17%)
Query: 47 VRQGESATLRCTIDDRV-TRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS-IMIQN 104
V +GE+ L C + + +V W R L + + T+ S + + +
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQ---------------TRGSRLRLHH 2782
Query: 105 VDVYDEGPYTCSVQTDNHPKTSRVHLIVQ--------VP-----PQIMNISSDITVNEGS 151
V D G Y C V + P + V + ++ VP P I S V EG
Sbjct: 2783 VSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQ 2842
Query: 152 SVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
++ L C+ G+ VTW L ++ + SGEY C
Sbjct: 2843 TLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 212 DVRKVKITVN-------------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFK 258
+ V +T+ P YI +A ++ V+ GQ L+C A+ W+K
Sbjct: 2903 EA-SVLVTIEPSSPGPIPAPGLAQPIYI-EASSSHVTEGQTLDLNCVVPGQAHAQVTWYK 2960
Query: 259 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG-NTNASITLYGP 314
L R + G S L VS D G Y C A + G AS T+ P
Sbjct: 2961 RGGSLPA-----RHQTHG--SQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVP 3010
Score = 47.4 bits (111), Expect = 2e-05
Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 32/231 (13%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQ---------VPPQIMNISSDITVNEGSSVTLLCLA 159
D G Y C V + P + V + ++ V P + SS V EG ++ L CL
Sbjct: 2401 DSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLV 2460
Query: 160 IGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
G+ VTW L + + SGEY C + + V +T
Sbjct: 2461 AGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEA-SVLVT 2519
Query: 220 VN------------YPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGL 267
+ YP I ++ + ++ G L+C ++ W+K L +
Sbjct: 2520 IQQRLSGSHSQGVAYPVRI-ESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPS-- 2576
Query: 268 DGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN--TNASITLYGPGA 316
R + G S L V+ D G Y C +N G+ T+ +T+ G G+
Sbjct: 2577 ---RHQIVG--SRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGS 2622
Score = 46.2 bits (108), Expect = 4e-05
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 12/119 (10%)
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-ITVNEGSSV 153
PTQ+ + N+ + + C ++D ++ + PPQ++ + I + G +V
Sbjct: 370 PTQFRCVSTNMCI--PASFHCDEESDCPDRSDEFGCM---PPQVVTPPRESIQASRGQTV 424
Query: 154 TLLCLAIGRPEPTVTWR----HLSVKEGQGFVSED--EYLEISDIKRDQSGEYECSALN 206
T C+AIG P P + WR H+ SE L I D+K G Y C A+N
Sbjct: 425 TFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMN 483
Score = 46.2 bits (108), Expect = 4e-05
Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 34/232 (14%)
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIV-QVPPQIMNISSD----ITVNEGSSVTLLCL 158
+V D G Y C+ + + TSR L+V + P + + ++ + +V G+ VT +C
Sbjct: 1735 SVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICT 1794
Query: 159 AIGR-PEPTVTWRHL-SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALN---------- 206
A + P T+ W L + K + + L I +++ +G Y C+ N
Sbjct: 1795 AKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTAT 1854
Query: 207 -DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLAT 265
V A + +PP ++ V GQ C A+ P +W T
Sbjct: 1855 LHVQASGTLSAPVVSIHPPQLT------VQPGQLAEFRCSATGSPTPTLEW--------T 1900
Query: 266 GLDGMRIENKGRM--STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPG 315
G G ++ K ++ L V D Y C A + G A L+ G
Sbjct: 1901 GGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHG 1952
Score = 37.4 bits (85), Expect = 0.020
Identities = 47/201 (23%), Positives = 74/201 (36%), Gaps = 25/201 (12%)
Query: 123 PKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLS---VKEGQG 179
P+T++ L+V+V P + V +G S +L C G P W V G
Sbjct: 1670 PETNQAPLVVEVHP------ARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQ 1723
Query: 180 FVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPY------ISKAKNTG 233
+ L ++ +G Y C+ N + + + ++ V P + + ++
Sbjct: 1724 QRHQGSELHFPSVQPSDAGVYICTCRN-LHQSNTSRAELLVTEAPSKPITVTVEEQRSQS 1782
Query: 234 VSVGQKGILSCEA-SAVPMAEFQWFKEETRLATG-LDGMRIENKGRMSTLTFFNVSEKDY 291
V G C A S P W TRL G L ++ G LT NV D
Sbjct: 1783 VRPGADVTFICTAKSKSPAYTLVW----TRLHNGKLPTRAMDFNG---ILTIRNVQLSDA 1835
Query: 292 GNYTCVATNKLGNTNASITLY 312
G Y C +N + TL+
Sbjct: 1836 GTYVCTGSNMFAMDQGTATLH 1856
Score = 32.0 bits (71), Expect = 0.83
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 1/69 (1%)
Query: 235 SVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNY 294
S GQ +C A VP W + + + + ++G TL +V E D G Y
Sbjct: 419 SRGQTVTFTCVAIGVPTPIINWRLNWGHIPSH-PRVTVTSEGGRGTLIIRDVKESDQGAY 477
Query: 295 TCVATNKLG 303
TC A N G
Sbjct: 478 TCEAMNARG 486
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 92.8 bits (229), Expect = 4e-19
Identities = 74/281 (26%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 44 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 163 PEPTVTW----RHLSVKE----GQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 211
P P++TW R++S +E G V + L + I+ +GEY C+A N +
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI-GQ 393
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGM 270
D + + + V Y P + G + ++CE A P A WF++ L ++ +
Sbjct: 394 DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+I N S L SE D+GNY C A N++G + L
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 50 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 107
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 165
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 166 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 218
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 219 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 275
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/186 (19%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 51 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 109
E TL C D + + W R++ +++ ++D +++ + S+ ++++ D
Sbjct: 323 EQVTLTCEASGDPIPSITW--RTSTRNISSEEKTLDGHMVVRSHARVS-SLTLKSIQYTD 379
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW 169
G Y C+ + ++L VQ P++ + T EG+ V + C P T++W
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATISW 438
Query: 170 RHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
++GQ S + YLE++ + G Y C+A+N + + +
Sbjct: 439 ----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Query: 218 ITVNYP 223
+ + P
Sbjct: 495 VQADTP 500
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 234 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 289
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 290 DYGNYTCVATNKLGN 304
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 92.8 bits (229), Expect = 4e-19
Identities = 74/281 (26%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 44 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 163 PEPTVTW----RHLSVKE----GQGFV---SEDEYLEISDIKRDQSGEYECSALNDVAAP 211
P P++TW R++S +E G V + L + I+ +GEY C+A N +
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTI-GQ 393
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGM 270
D + + + V Y P + G + ++CE A P A WF++ L ++ +
Sbjct: 394 DSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+I N S L SE D+GNY C A N++G + L
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 50 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 107
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 165
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 166 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 218
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 219 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 275
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/186 (19%), Positives = 79/186 (42%), Gaps = 21/186 (11%)
Query: 51 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 109
E TL C D + + W R++ +++ ++D +++ + S+ ++++ D
Sbjct: 323 EQVTLTCEASGDPIPSITW--RTSTRNISSEEKTLDGHMVVRSHARVS-SLTLKSIQYTD 379
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW 169
G Y C+ + ++L VQ P++ + T EG+ V + C P T++W
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSATISW 438
Query: 170 RHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
++GQ S + YLE++ + G Y C+A+N + + +
Sbjct: 439 ----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 494
Query: 218 ITVNYP 223
+ + P
Sbjct: 495 VQADTP 500
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 234 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 289
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 290 DYGNYTCVATNKLGN 304
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 95 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 650 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 709
Query: 151 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 206
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 710 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 769
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 770 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 828
Query: 265 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 829 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 874
Score = 92.0 bits (227), Expect = 7e-19
Identities = 83/302 (27%), Positives = 125/302 (41%), Gaps = 30/302 (9%)
Query: 21 LLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGN 79
LL L P PV GD + ++ VTV + +L+C + + V ++WL
Sbjct: 1645 LLVLTP---PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL------ 1693
Query: 80 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 139
+S PR+ +L + + + +V D Y C + L VQVPP+I
Sbjct: 1694 -PFSPSPRLQVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 1749
Query: 140 NISSD-ITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKR 194
+ + +T SSV+L C P P VTW + LS+ E + L++ +
Sbjct: 1750 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 1809
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAV 249
SG Y C ALN A D + V+++V PP +A V VG K +LSCE A+
Sbjct: 1810 SDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDAL 1868
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P W+K+ L + R L D G Y+C +N G +
Sbjct: 1869 PEPTVTWYKDGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1925
Query: 310 TL 311
TL
Sbjct: 1926 TL 1927
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2870
Query: 160 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 2871 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 2929
Query: 216 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 2930 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 2984
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+ STL VS +D G Y C A N++G T A
Sbjct: 2985 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 3017
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 2639 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2698
Query: 169 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 2699 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 2757
Query: 225 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 2758 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 2813
Query: 284 FNVSEKDYGNYTCVATNKLGN 304
+ S +D GNY C+A N G+
Sbjct: 2814 AHASPEDAGNYLCIAKNSAGS 2834
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 43 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 99
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 1849 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 1895
Query: 100 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 156
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 1954
Query: 157 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 1955 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 2012
Query: 213 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 2013 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 2071
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G + +L + D G YTCVA N G
Sbjct: 2072 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 166
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 1039 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1098
Query: 167 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 1099 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 1157
Query: 223 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 1158 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 1216
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 317
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 1217 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1255
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 165
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 376 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 435
Query: 166 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 221
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 436 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 494
Query: 222 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 495 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 551
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 321
+TL +V G + C ATN+ G A + + G GV
Sbjct: 552 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 594
Score = 76.3 bits (186), Expect = 4e-14
Identities = 79/312 (25%), Positives = 127/312 (40%), Gaps = 34/312 (10%)
Query: 44 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 888 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 938
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 162
DV+D G YTC +L V V P + S +TV EG +L C G
Sbjct: 939 RADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGV 998
Query: 163 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 212
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 999 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 1053
Query: 213 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 268
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 1054 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 1112
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 326
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 1113 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 1170
Query: 327 ALACLWLSGTLL 338
A L TLL
Sbjct: 1171 ITAALHSPLTLL 1182
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 155
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 2176 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2235
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 211
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 2236 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 2290
Query: 212 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 2291 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 2346
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+EN R + + + +D G YTC+A + G
Sbjct: 2347 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 2375
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 170
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2791
Query: 171 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 227
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 2792 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 2850
Query: 228 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 286
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 2851 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 2907
Query: 287 SEKDYGNYTCVATNKLGNTNASITL 311
+D G YTC A N +G + L
Sbjct: 2908 EGQDAGTYTCTAENAVGRARRRVHL 2932
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 147
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 1401 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKT 1460
Query: 148 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 199
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 1461 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1516
Query: 200 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 238
Y C A N VA D + + + PP K + +
Sbjct: 1517 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1575
Query: 239 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 1576 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 1632
Query: 299 TNKLG 303
+N++G
Sbjct: 1633 SNEVG 1637
Score = 72.4 bits (176), Expect = 6e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 166
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 1226 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1285
Query: 167 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 1286 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 1344
Query: 223 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 268
P I S + V+V L CEA A P W K+ +L G
Sbjct: 1345 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 1404
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G++I N ++D G YTCV TN+LG
Sbjct: 1405 GLQI-----------LNAQKEDAGQYTCVVTNELG 1428
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 141
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 2249 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2308
Query: 142 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 198
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 2309 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 2364
Query: 199 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 254
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 2365 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 2422
Query: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 311
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 2423 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 2479
Query: 312 ------YGPGAVIDGVNSAS 325
GP AV VN +
Sbjct: 2480 TVPTIRSGPPAVNVSVNQTA 2499
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 155
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 1615 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1674
Query: 156 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 1675 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1734
Query: 212 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 1735 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1793
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ TL D G YTC A N G + L
Sbjct: 1794 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 1832
Score = 69.3 bits (168), Expect = 5e-12
Identities = 82/314 (26%), Positives = 127/314 (40%), Gaps = 33/314 (10%)
Query: 25 VPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWS 83
VPT +RSG P A+ NV+V Q +A L C D V+W D+
Sbjct: 2481 VPT---IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVP 2521
Query: 84 IDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS 143
+DPR P + S+ IQ V D G Y C L V PP I S
Sbjct: 2522 LDPRSPRFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPS 2580
Query: 144 DITVNEGSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQS 197
++T+ + L C A G P+P V W +++G + L ++ S
Sbjct: 2581 NLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 2640
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQW 256
++EC N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W
Sbjct: 2641 AQFECVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSW 2699
Query: 257 FKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPG 315
K +L G R+ G + + G YTC A N G + + L
Sbjct: 2700 SKAGAQLGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQAS 2756
Query: 316 AVIDGVNSASRALA 329
V+ + S RA+A
Sbjct: 2757 PVVKPLPSVVRAVA 2770
Score = 67.8 bits (164), Expect = 1e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 853 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 912
Query: 169 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 913 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGRSEKHYNLNVWVAP 971
Query: 225 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 281
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 972 VFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 1031
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++++ G YTC +N +GN++ + L
Sbjct: 1032 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 1059
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 157
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 274 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 333
Query: 158 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 334 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 392
Query: 214 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 393 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 452
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+E G S L + E G Y+CVA++ G
Sbjct: 453 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 483
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 47 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 2089
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 161
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 2090 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 2148
Query: 162 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 2149 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 2207
Query: 218 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 273
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 2208 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 2262
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +L V D G Y+CVA ++ G L
Sbjct: 2263 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 2297
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2505
Query: 160 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 2506 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 2564
Query: 216 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 270
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 2565 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2624
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 319
N L +D + CV +N++G + +T++ P + D
Sbjct: 2625 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2670
Score = 58.9 bits (141), Expect = 6e-09
Identities = 38/111 (34%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 157 CLAIGRPEPTVTWRHLSVKE---GQGFVS--EDEYLEISDIKRDQSGEYECSALNDVAAP 211
C G P+P VTWR E GQ V+ E+ L ++ + SG+YEC A N+V +
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGST 83
Query: 212 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 259
R+ K+ V PP I + N GQ L C+A+ P+ E W K+
Sbjct: 84 S-RRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKD 133
Score = 58.9 bits (141), Expect = 6e-09
Identities = 53/185 (28%), Positives = 76/185 (41%), Gaps = 26/185 (14%)
Query: 135 PPQIMNISS--DITVNEGSSVTLLCLAIGRPEPTVTWR-----------HLSVKEGQGFV 181
PP ++ + ++ G+ V L C G P P V W HL V+E
Sbjct: 215 PPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE----- 269
Query: 182 SEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKG 240
+ + L I+ G Y+C A + A R ++ V+ PP I + TG V+V +
Sbjct: 270 -DGQVLRITGSHVGDEGRYQCVAFSP-AGQQARDFQLRVHAPPTIWGSNETGEVAVMEDH 327
Query: 241 I--LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
+ L CEA VP WFK+ L T + GR L D G YTC A
Sbjct: 328 LVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRG-GRQ--LQLGRAQSSDAGVYTCKA 384
Query: 299 TNKLG 303
+N +G
Sbjct: 385 SNAVG 389
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 166
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 3000 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 3058
Query: 167 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 3059 IHW----IKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVL 3114
Query: 220 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 273
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 3115 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 3170
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+L NV D G Y CVA N LG+ A
Sbjct: 3171 ------SLWLENVETGDAGTYDCVAHNLLGSATA 3198
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ I + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 3081 SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3140
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 211
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 3141 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 3196
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 252
R + V P S TGV G+K G+ + S + A
Sbjct: 3197 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 3237
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/241 (22%), Positives = 86/241 (35%), Gaps = 38/241 (15%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVN--EGSSVTLL 156
S+ + +V D G Y C + + R L+V VPP I V+ G S+TL
Sbjct: 58 SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLE 117
Query: 157 CLAIGRPEPTVTWRH-------------------LSVKEGQGFVSEDEYLEISDIKRDQS 197
C A G P P + W G + E + L I+ +S
Sbjct: 118 CDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRS 177
Query: 198 GE--YECSALNDVAAPDVRKV----------KITVNYPPYISKAKNTGVSVGQKGI---L 242
G + AP + + PP + A +G G L
Sbjct: 178 GRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVEL 237
Query: 243 SCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 302
C S VP + +W K+ + G ++++ G++ +T +V D G Y CVA +
Sbjct: 238 QCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG--DEGRYQCVAFSPA 295
Query: 303 G 303
G
Sbjct: 296 G 296
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 17 VSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTIL 75
V+ +++ LV PV F ++TVR G+ LRC T + WL L
Sbjct: 3105 VAKKVVILVLQSAPV------FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 3158
Query: 76 YAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP 135
A + T S+ ++NV+ D G Y C T+R L+V+
Sbjct: 3159 RASR-----------RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGE 3207
Query: 136 PQ 137
PQ
Sbjct: 3208 PQ 3209
Score = 35.0 bits (79), Expect = 0.098
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 14/98 (14%)
Query: 244 CEASAVPMAEFQWFK-EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKL 302
C P + W K + G G+ + +G +L +VS D G+Y C ATN++
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG---SLFLASVSPADSGDYECQATNEV 80
Query: 303 GNTN--ASITLYGPGAV--------IDGVNSASRALAC 330
G+T+ A + +Y P ++ + G+ S L C
Sbjct: 81 GSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLEC 118
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 92.4 bits (228), Expect = 5e-19
Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 14/228 (6%)
Query: 95 PTQYSI----MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEG 150
P YS+ I+ VD+ DEG YTC+ V L V VPP I + V E
Sbjct: 559 PVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLEN 618
Query: 151 SSVTLLCLAIGRPEPTVTW--RHLSVKEGQGF-VSED-EYLEISDIKRDQSGEYECSALN 206
+SVTL CLA G P P V+W H V G VS D L I + +G Y C A N
Sbjct: 619 ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 678
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNT--GVSVGQKGILSCEASAVPMAEFQWFKEETRLA 264
+ ++R + VN PP I+ + V V L+C A+ P W K+ ++
Sbjct: 679 VAGSTELR-YGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS 737
Query: 265 -TGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
G G+++ GR+ TL S D G Y+CVA + +G + L
Sbjct: 738 PAGTPGLQVFPGGRVLTLASARAS--DSGRYSCVAVSAVGEDRQDVVL 783
Score = 92.0 bits (227), Expect = 7e-19
Identities = 83/302 (27%), Positives = 125/302 (41%), Gaps = 30/302 (9%)
Query: 21 LLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRC-TIDDRVTRVAWLNRSTILYAGN 79
LL L P PV GD + ++ VTV + +L+C + + V ++WL
Sbjct: 1554 LLVLTP---PVILGDTE--ELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGL------ 1602
Query: 80 DKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM 139
+S PR+ +L + + + +V D Y C + L VQVPP+I
Sbjct: 1603 -PFSPSPRLQVLEDGQV---LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA 1658
Query: 140 NISSD-ITVNEGSSVTLLCLAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKR 194
+ + +T SSV+L C P P VTW + LS+ E + L++ +
Sbjct: 1659 GLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARL 1718
Query: 195 DQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTG-----VSVGQKGILSCEASAV 249
SG Y C ALN A D + V+++V PP +A V VG K +LSCE A+
Sbjct: 1719 SDSGMYTCEALN-AAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDAL 1777
Query: 250 PMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASI 309
P W+K+ L + R L D G Y+C +N G +
Sbjct: 1778 PEPTVTWYKDGQPLVLAQRTQALRGGQR---LEIQEAQVSDKGLYSCKVSNVAGEAVRTF 1834
Query: 310 TL 311
TL
Sbjct: 1835 TL 1836
Score = 88.6 bits (218), Expect = 7e-18
Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 11/213 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ I + D G Y C + + L+VQVPP I N D++ EGS L C A
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKA 2779
Query: 160 IGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G PEP +TW + +S EG+ + L + +++ +G Y C+A N V R+
Sbjct: 2780 RGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRAR-RR 2838
Query: 216 VKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIEN 274
V +T+ P + + + + +G + L C A P W + + G +
Sbjct: 2839 VHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSE 2893
Query: 275 KGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+ STL VS +D G Y C A N++G T A
Sbjct: 2894 QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQA 2926
Score = 85.9 bits (211), Expect = 5e-17
Identities = 60/201 (29%), Positives = 87/201 (43%), Gaps = 10/201 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D + C V + + V VPP I + +D TV + V L C + G P PTV+
Sbjct: 2548 DSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 2607
Query: 169 WRHLSVK---EGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W + G G+ VS LEI +G Y CSA N + V +TV P
Sbjct: 2608 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAH-KHVFLTVQASP 2666
Query: 225 YISKAKNTGVSVGQKGI-LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTF 283
+ + +V ++ + L CEAS +P W KE +ATG+ + L
Sbjct: 2667 VVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPG----GQLRI 2722
Query: 284 FNVSEKDYGNYTCVATNKLGN 304
+ S +D GNY C+A N G+
Sbjct: 2723 AHASPEDAGNYLCIAKNSAGS 2743
Score = 81.3 bits (199), Expect = 1e-15
Identities = 83/275 (30%), Positives = 114/275 (41%), Gaps = 31/275 (11%)
Query: 43 DNVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYS--- 99
D V VR G+ A L C D L T+ W D + ++L
Sbjct: 1758 DAVLVRVGDKAVLSCETDA-------LPEPTVT------WYKDGQPLVLAQRTQALRGGQ 1804
Query: 100 -IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNE--GSSVTLL 156
+ IQ V D+G Y+C V L VQVPP N ++ TV++ GS + L
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTE-TVSQVAGSPLVLT 1863
Query: 157 CLAIGRPEPTVTW--RHLSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPD 212
C G P PTVTW + V+ G VS L++S ++ Q+G Y C A N A +
Sbjct: 1864 CDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQA--E 1921
Query: 213 VRK-VKITVNYPPYISK---AKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
RK + V P I A+ V GQ+ L CEA P + W K+ + L +
Sbjct: 1922 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDM- 1980
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G + +L + D G YTCVA N G
Sbjct: 1981 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 110 EGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS---SDITVNEGSSVTLLCLAIGRPEPT 166
EG YTC + + L V VPPQI + ++V + TL C A G+P PT
Sbjct: 948 EGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT 1007
Query: 167 VTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
VTW + + G ++ + L + + +G Y C A N +A RK +++V
Sbjct: 1008 VTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAEN-LAGRAERKFELSVLV 1066
Query: 223 PPY----ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + N ++ L CEA +P +WF+ E ++ G D + G M
Sbjct: 1067 PPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAG-GWM 1125
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNT--NASITLYGPGAV 317
+T E+D G Y+C+A+N+ G N S+ + P ++
Sbjct: 1126 LKMT--QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSI 1164
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/223 (29%), Positives = 92/223 (41%), Gaps = 14/223 (6%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD---ITVNEGSSVTLLCLAIGRPEP 165
D G YTC L V VPP I + G V L C+A G P P
Sbjct: 285 DAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSP 344
Query: 166 TVTWRH--LSVKEG--QGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 221
T++W H L V E ++ L + SG Y C A + A V + + V
Sbjct: 345 TLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVA-SSPAGEAVLQYSVEVQ 403
Query: 222 YPPYISKAKNTG---VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRM 278
PP + A+ G VGQ L C+AS P+ QW + R A L G+++ ++G
Sbjct: 404 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL-QNGRPAEELAGVQVASQG-- 460
Query: 279 STLTFFNVSEKDYGNYTCVATNKLGNTNASITLYGPGAVIDGV 321
+TL +V G + C ATN+ G A + + G GV
Sbjct: 461 TTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGV 503
Score = 76.3 bits (186), Expect = 4e-14
Identities = 60/215 (27%), Positives = 97/215 (45%), Gaps = 24/215 (11%)
Query: 98 YSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI--MNISSDITVNEGSSVTL 155
+++ I V + D G +TC + L VQVPP + + +D+ V GS V L
Sbjct: 2085 HTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVEL 2144
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSED----EYLEISDIKRDQSGEYECSALNDVAAP 211
C A G P P V+W +K+G+ +S+ L++ + SG Y C A+++ A
Sbjct: 2145 PCEARGVPLPLVSW----MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSE-AGE 2199
Query: 212 DVRKVKITVNYPPYI---SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLD 268
R ++TV PP+I + ++ G L C+A P W K+ L
Sbjct: 2200 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT---- 2255
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+EN R + + + +D G YTC+A + G
Sbjct: 2256 --RLENNSRATRV----LRVRDAGLYTCLAESPAG 2284
Score = 75.9 bits (185), Expect = 5e-14
Identities = 56/205 (27%), Positives = 80/205 (39%), Gaps = 8/205 (3%)
Query: 111 GPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWR 170
G YTCS + V L VQ P + + S + V L C A G P PT+TW+
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 2700
Query: 171 HLSVKEGQGF---VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYIS 227
+ G V L I+ + +G Y C A N A + K ++ V PP I
Sbjct: 2701 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS-AGSAMGKTRLVVQVPPVIE 2759
Query: 228 KA-KNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNV 286
+ + G L C+A P W K+ ++ I+ G L N+
Sbjct: 2760 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNL 2816
Query: 287 SEKDYGNYTCVATNKLGNTNASITL 311
+D G YTC A N +G + L
Sbjct: 2817 EGQDAGTYTCTAENAVGRARRRVHL 2841
Score = 75.5 bits (184), Expect = 7e-14
Identities = 79/312 (25%), Positives = 126/312 (40%), Gaps = 34/312 (10%)
Query: 44 NVTVRQGESATLRCTIDDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQ 103
NV+V ES L C + +L D ++PR + ++ + +
Sbjct: 797 NVSVVANESVALECQ--------SHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-LQVD 847
Query: 104 NVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQI-MNISSDITVNEGSSVTLLCLAIGR 162
DV+D G YTC +L V V P + S +TV EG L C G
Sbjct: 848 RADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGV 907
Query: 163 PEPTVTWRHLSVKEGQGFVSEDEYLE----------ISDIKRDQSGEYECSALNDVAAPD 212
P P ++WR K+GQ E L+ + + Q G Y C N V
Sbjct: 908 PFPKISWR----KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN-VVGNS 962
Query: 213 VRKVKITVNYPPYISKAKN--TGVSVGQKGI--LSCEASAVPMAEFQWFKEETRLATGLD 268
+ +++ V+ PP I+ + T VSV Q G+ L C A+ P W ++ + L
Sbjct: 963 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAEL- 1021
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVIDGVNSASR 326
G++++N+G+ +L G Y+CVA N G +++ P +I ++ +
Sbjct: 1022 GLQLQNQGQ--SLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTN 1079
Query: 327 ALACLWLSGTLL 338
A L TLL
Sbjct: 1080 ITAALHSPLTLL 1091
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/245 (23%), Positives = 96/245 (39%), Gaps = 44/245 (17%)
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNIS-------SDITV 147
P + + I N D G YTC V + H+ V +PP I ++
Sbjct: 1310 PGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKT 1369
Query: 148 NEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQ--------GFVSEDEYLEISDIKRDQSGE 199
S++TL C + P PT+ W K+GQ + E L+I + SG
Sbjct: 1370 KVNSTLTLECESWAVPPPTIRW----YKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1425
Query: 200 YECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV---------------------GQ 238
Y C A N VA D + + + PP K + +
Sbjct: 1426 YLCVATN-VAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1484
Query: 239 KGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVA 298
L C+ +A+P + W++E+ L+ G D + + GR+ + V ++ G Y+C A
Sbjct: 1485 PAYLYCDTNAIPPPDLTWYREDQPLSAG-DEVSVLQGGRVLQIPL--VRAENAGRYSCKA 1541
Query: 299 TNKLG 303
+N++G
Sbjct: 1542 SNEVG 1546
Score = 73.2 bits (178), Expect = 3e-13
Identities = 74/285 (25%), Positives = 111/285 (38%), Gaps = 38/285 (13%)
Query: 44 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTIL--------YAGNDKWSIDPRVIILVNT 94
NV+ G+S TL C + V + WL + ++ Y + W +L
Sbjct: 27 NVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLL--- 83
Query: 95 PTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSS 152
S+ + D G Y+C + HL+V PP ++ + ++ G+
Sbjct: 84 DEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGAD 143
Query: 153 VTLLCLAIGRPEPTVTWR-----------HLSVKEGQGFVSEDEYLEISDIKRDQSGEYE 201
V L C G P P V W HL V+E + + L I+ G Y+
Sbjct: 144 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE------DGQVLRITGSHVGDEGRYQ 197
Query: 202 CSALNDVAAPDVRKVKITVNYPPYISKAKNTG-VSVGQKGI--LSCEASAVPMAEFQWFK 258
C A + A R ++ V+ PP I + TG V+V + + L CEA VP WFK
Sbjct: 198 CVAFSP-AGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFK 256
Query: 259 EETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ L T + GR L D G YTC A+N +G
Sbjct: 257 DGALLPTSTKVVYTRG-GRQ--LQLGRAQSSDAGVYTCKASNAVG 298
Score = 72.4 bits (176), Expect = 6e-13
Identities = 58/215 (26%), Positives = 86/215 (40%), Gaps = 32/215 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN--ISSDITVNEGSSVTLLCLAIGRPEPT 166
D G Y+C + + V VPP I N + I V +G + L+C G P+P
Sbjct: 1135 DSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1194
Query: 167 VTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNY 222
+TW R L+ + + L++ +G Y C A N V + +++V
Sbjct: 1195 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK-TKHFQLSVLL 1253
Query: 223 PPYI------SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE--------ETRLATGLD 268
P I S + V+V L CEA A P W K+ +L G
Sbjct: 1254 APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH 1313
Query: 269 GMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
G++I N ++D G YTCV TN+LG
Sbjct: 1314 GLQI-----------LNAQKEDAGQYTCVVTNELG 1337
Score = 71.6 bits (174), Expect = 9e-13
Identities = 63/260 (24%), Positives = 109/260 (41%), Gaps = 25/260 (9%)
Query: 82 WSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNI 141
W D ++ + S+ ++ V D G Y+C ++ L V PP I +
Sbjct: 2158 WMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDS 2217
Query: 142 S--SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISDIKR-DQSG 198
+++++ G+ + LLC A G P+P +TW K+GQ + + + R +G
Sbjct: 2218 GQPTELSLTPGAPMELLCDAQGTPQPNITWH----KDGQALTRLENNSRATRVLRVRDAG 2273
Query: 199 EYECSALNDVAAPDVRKVKITVNYPPYISKAKN----TGVSVGQKGILSCEASAVPMAEF 254
Y C A + A + + ++ V PP I + G++ GQ +L C A P +
Sbjct: 2274 LYTCLAESPAGAIE-KSFRVRVQAPPNIVGPRGPRFVVGLAPGQL-VLECSVEAEPAPKI 2331
Query: 255 QWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL--- 311
W ++ L + +GR L +S D G+Y+C A N G+T+ + +
Sbjct: 2332 TWHRDGIVLQEDAH-TQFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH 2388
Query: 312 ------YGPGAVIDGVNSAS 325
GP AV VN +
Sbjct: 2389 TVPTIRSGPPAVNVSVNQTA 2408
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/222 (24%), Positives = 89/222 (40%), Gaps = 14/222 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMN----ISSDITVNEGSSVTL 155
+ I V + G Y+C + L+V PP I+ + ++TVN S+V+L
Sbjct: 1524 LQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1583
Query: 156 LCLAIGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAP 211
C A+G P PT++W S + + + L++S + + Y C A N +
Sbjct: 1584 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1643
Query: 212 DVRKVKITVNYPPYIS--KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ + + V PP I+ + + L C+ A P E W+K+ L+ G +
Sbjct: 1644 E-KLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV 1702
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ TL D G YTC A N G + L
Sbjct: 1703 FLLPG---THTLQLGRARLSDSGMYTCEALNAAGRDQKLVQL 1741
Score = 69.3 bits (168), Expect = 5e-12
Identities = 82/314 (26%), Positives = 127/314 (40%), Gaps = 33/314 (10%)
Query: 25 VPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWS 83
VPT +RSG P A+ NV+V Q +A L C D V+W D+
Sbjct: 2390 VPT---IRSG----PPAV-NVSVNQ--TALLPCQADGVPAPLVSWRK---------DRVP 2430
Query: 84 IDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISS 143
+DPR P + S+ IQ V D G Y C L V PP I S
Sbjct: 2431 LDPRSPRFEILP-EGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPS 2489
Query: 144 DITVNEGSSVTLLCLAIGRPEPTVTW------RHLSVKEGQGFVSEDEYLEISDIKRDQS 197
++T+ + L C A G P+P V W +++G + L ++ S
Sbjct: 2490 NLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 2549
Query: 198 GEYECSALNDVAAPDVRKVKITVNYPPYISKAK-NTGVSVGQKGILSCEASAVPMAEFQW 256
++EC N+V R ++TV+ PP I+ + + V++ +L+C ++ +P W
Sbjct: 2550 AQFECVVSNEVGEAH-RLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSW 2608
Query: 257 FKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL-YGPG 315
K +L G R+ G + + G YTC A N G + + L
Sbjct: 2609 SKAGAQLGARGSGYRVSPSGALEIGQALPIHA---GRYTCSARNSAGVAHKHVFLTVQAS 2665
Query: 316 AVIDGVNSASRALA 329
V+ + S RA+A
Sbjct: 2666 PVVKPLPSVVRAVA 2679
Score = 67.4 bits (163), Expect = 2e-11
Identities = 54/210 (25%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVT 168
D G Y+C + V L V +PP I+ +++V SV L C + P P ++
Sbjct: 762 DSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLS 821
Query: 169 W----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224
W R L + G ++ L++ +G Y C ALN A + + V P
Sbjct: 822 WWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQ-AGHSEKHYNLNVWVAP 880
Query: 225 Y--ISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL-ATGLDGMRIENKGRMSTL 281
+ ++ V G LSCE VP + W K+ L G + GR+ L
Sbjct: 881 VFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 940
Query: 282 TFFNVSEKDYGNYTCVATNKLGNTNASITL 311
++++ G YTC +N +GN++ + L
Sbjct: 941 GQAQLAQE--GTYTCECSNVVGNSSQDLQL 968
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/214 (28%), Positives = 84/214 (39%), Gaps = 14/214 (6%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLC 157
+ I V DEG Y C + + L V PP I N + ++ V E V LLC
Sbjct: 183 LRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLC 242
Query: 158 LAIGRPEPTVTW----RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
A G P P +TW L + L++ + +G Y C A N V A +
Sbjct: 243 EARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAE- 301
Query: 214 RKVKITVNYPPYISKAKNTGVSV----GQKGILSCEASAVPMAEFQWFKEETRLATGLDG 269
+ ++ V PP I A V G+ L C A P W E +A +
Sbjct: 302 KATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNES 361
Query: 270 MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
R+E G S L + E G Y+CVA++ G
Sbjct: 362 -RLETDG--SVLRLESPGEASSGLYSCVASSPAG 392
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/278 (25%), Positives = 114/278 (41%), Gaps = 31/278 (11%)
Query: 47 VRQGESATLRCTIDDRVTR-VAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
V +G+ L C D + VAWL + L G D + P + ++ S++++ +
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPL--GQD---MGPHLRFYLDGG---SLVLKGL 1998
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIM---NISSDITVNEGSSVTLLCLAIG 161
D G YTC V + + +R+H + V VPP I + S + G VT++C G
Sbjct: 1999 RASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRG 2057
Query: 162 RPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
P V+W L + + L IS ++ +G + C A + D R
Sbjct: 2058 SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD-RNFT 2116
Query: 218 ITVNYPPYISKAKNTGVSVGQKGI---LSCEASAVPMAEFQWFKE-ETRLATGLDGMRIE 273
+ V PP + + V +G L CEA VP+ W K+ E L+ L+
Sbjct: 2117 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLE----- 2171
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ +L V D G Y+CVA ++ G L
Sbjct: 2172 ---QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQL 2206
Score = 60.5 bits (145), Expect = 2e-09
Identities = 53/231 (22%), Positives = 94/231 (40%), Gaps = 17/231 (7%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLA 159
+ +Q + D G Y+C+ + + + + P I + + V+ + L C A
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQA 2414
Query: 160 IGRPEPTVTWRH----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRK 215
G P P V+WR L + + + + L I + +G Y C A N A D +
Sbjct: 2415 DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNS-AGSDRQG 2473
Query: 216 VKITVNYPPYISKA-KNTGVSVGQKGILSCEASAVPMAEFQWFKE----ETRLATGLDGM 270
+ V PP I+ + N ++ +L CEAS P W+K+ + RL G +
Sbjct: 2474 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2533
Query: 271 RIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA--SITLYGPGAVID 319
N L +D + CV +N++G + +T++ P + D
Sbjct: 2534 LPSN-----ALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIAD 2579
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 30/214 (14%)
Query: 109 DEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPT 166
D G Y C + + +T V + V+ P + + V G S+ L C+ G P P
Sbjct: 2909 DSGTYVCWAE-NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 2967
Query: 167 VTWRHLSVKEGQGFVS-------EDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKIT 219
+ W +K+G ++ L I +RD +G Y+C A N++ + +
Sbjct: 2968 IHW----IKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVAKKVVILVL 3023
Query: 220 VNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQW------FKEETRLATGLDGMRIE 273
+ P + + ++ V G L C+A+ P +W + RL T DG
Sbjct: 3024 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---- 3079
Query: 274 NKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 307
+L NV D G Y CVA N LG+ A
Sbjct: 3080 ------SLWLENVETGDAGTYDCVAHNLLGSATA 3107
Score = 55.1 bits (131), Expect = 9e-08
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCL 158
S+ I+ + D G Y C + + V L++Q P D+TV G V L C
Sbjct: 2990 SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQ 3049
Query: 159 AIGRPEPTVTWRHLSVKEGQGFVSE-------DEYLEISDIKRDQSGEYECSALNDVAAP 211
A G P PT+ W ++ GQ + D L + +++ +G Y+C A N + +
Sbjct: 3050 ATGEPTPTIEW----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSA 3105
Query: 212 DVRKVKITVNYPPYISKAKNTGVSVGQK-GILSCEASAVPMA 252
R + V P S TGV G+K G+ + S + A
Sbjct: 3106 TARAF-LVVRGEPQGSWGSMTGVINGRKFGVATLNTSVMQEA 3146
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/194 (25%), Positives = 72/194 (37%), Gaps = 27/194 (13%)
Query: 134 VPPQIMNISSDITVN--EGSSVTLLCLAIGRPEPTVTWRH-------------------L 172
VPP I V+ G S+TL C A G P P + W
Sbjct: 15 VPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGW 74
Query: 173 SVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNT 232
G + E + L I+ SG Y C A N R + V PP + A
Sbjct: 75 GQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQ-RDFHLLVLTPPSVLGAGAA 133
Query: 233 GVSVGQKGI---LSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEK 289
+G G L C S VP + +W K+ + G ++++ G++ +T +V
Sbjct: 134 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVG-- 191
Query: 290 DYGNYTCVATNKLG 303
D G Y CVA + G
Sbjct: 192 DEGRYQCVAFSPAG 205
Score = 37.7 bits (86), Expect = 0.015
Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 18/122 (14%)
Query: 17 VSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTIL 75
V+ +++ LV PV F ++TVR G+ LRC T + WL L
Sbjct: 3014 VAKKVVILVLQSAPV------FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 3067
Query: 76 YAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP 135
A + T S+ ++NV+ D G Y C T+R L+V+
Sbjct: 3068 RASR-----------RLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGE 3116
Query: 136 PQ 137
PQ
Sbjct: 3117 PQ 3118
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 92.0 bits (227), Expect = 7e-19
Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 32/285 (11%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
+ P+ N T +GE T C ++W R+ L N+K+ IL +
Sbjct: 212 SMPQKSFNATAERGEEMTFSCRASGSPEPAISWF-RNGKLIEENEKY-------ILKGSN 263
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
T+ + ++N+ D GPY C + L V V P I+ + ++ T G VTL
Sbjct: 264 TE--LTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQ-VTL 320
Query: 156 LCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLE---------------ISDIKRDQSGEY 200
+C A G P P +TW+ +G F D+ L+ I D+K SG Y
Sbjct: 321 VCDAEGEPIPEITWKR--AVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRY 378
Query: 201 ECSALNDVAAPDVRKVKITVNYPP-YISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKE 259
+C A + + + + + + Y P +IS G +SC+ + P A W ++
Sbjct: 379 DCEAASRIGGHQ-KSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRD 437
Query: 260 ETRL-ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLG 303
+ L A ++ + GR L S+ D+G Y C ATN +G
Sbjct: 438 KLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 88.2 bits (217), Expect = 1e-17
Identities = 82/292 (28%), Positives = 127/292 (43%), Gaps = 29/292 (9%)
Query: 37 TFPKAMDNVTVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSI-DPRVIILVNT 94
TF + + +QGE A + C + V+WL Y + +I D R +L N
Sbjct: 116 TFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWL------YHNEEVTTISDNRFAMLANN 169
Query: 95 PTQYSIMIQNVDVYDEGPYTCS--VQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEG 150
++ I N++ DEG Y C V+ + +IV VPP I S + T G
Sbjct: 170 ----NLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERG 225
Query: 151 SSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEIS--DIKRDQSGEYECSALN 206
+T C A G PEP ++W ++E + ++ + E++ +I G Y C A N
Sbjct: 226 EEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATN 285
Query: 207 DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEE-----T 261
A D ++ + V P+I + KN + L C+A P+ E W + T
Sbjct: 286 K-AGEDEKQAFLQVFVQPHIIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFT 344
Query: 262 RLATGLDGMRIENKGR--MSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
LDG RIE KG+ S+L +V D G Y C A +++G S+ L
Sbjct: 345 EGDKSLDG-RIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYL 395
Score = 38.5 bits (88), Expect = 0.009
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
Query: 234 VSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGN 293
+SVG+ +C A P + W+ + + ++ +G S LT +N + +D G
Sbjct: 32 LSVGESKFFTCTAIGEPES-IDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGI 90
Query: 294 YTCVATNKLGNT 305
Y C AT+ G T
Sbjct: 91 YRCQATDAKGQT 102
Score = 30.8 bits (68), Expect = 1.9
Identities = 36/171 (21%), Positives = 64/171 (37%), Gaps = 29/171 (16%)
Query: 143 SDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY----------LEISDI 192
S + ++ G S C AIG PE ++ W + +G+ +S L I +
Sbjct: 28 SKVELSVGESKFFTCTAIGEPE-SIDWYN---PQGEKIISTQRVVVQKEGVRSRLTIYNA 83
Query: 193 KRDQSGEYECSALN----DVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASA 248
+ +G Y C A + A V ++ + + +S + G+ + C S+
Sbjct: 84 NIEDAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQE---FKQGEDAEVVCRVSS 140
Query: 249 VPMAEFQWFKEETRLATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTC 296
P W + T D N+ M + L N+++ D G Y C
Sbjct: 141 SPAPAVSWLYHNEEVTTISD-----NRFAMLANNNLQILNINKSDEGIYRC 186
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 91.7 bits (226), Expect = 9e-19
Identities = 72/291 (24%), Positives = 119/291 (40%), Gaps = 31/291 (10%)
Query: 44 NVTVRQGESATLRCTIDD-RVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
N T G+S TL C + ++W + D D + I + + I
Sbjct: 222 NATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED----DEKYIF---SDDSSQLTI 274
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGR 162
+ VD DE Y C + + + +HL V P+I + + + VTL C A G
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 163 PEPTVTW----RHLSVKEGQGFVSEDEY-----------------LEISDIKRDQSGEYE 201
P P++TW R++S +E + ++ L + I+ +GEY
Sbjct: 335 PIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 394
Query: 202 CSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEET 261
C+A N + D + + + V Y P + G + ++CE A P A WF++
Sbjct: 395 CTASNTI-GQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQ 453
Query: 262 RL-ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
L ++ ++I N S L SE D+GNY C A N++G + L
Sbjct: 454 LLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFIL 504
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/276 (24%), Positives = 119/276 (43%), Gaps = 21/276 (7%)
Query: 50 GESATLRCTI--DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDV 107
GES C + D + ++W + + N + R+ ++ N + ++ I N ++
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQ-----RISVVWNDDSSSTLTIYNANI 88
Query: 108 YDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIM--NISSDITVNEGSSVTLLCLAIGRPEP 165
D G Y C V T S + V++ ++M N + EG ++C + P
Sbjct: 89 DDAGIYKCVV-TGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPP 147
Query: 166 TVTWRH-----LSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV--RKVKI 218
T+ W+H + K+ + V + YL+I IK+ G Y C +A ++ + +++
Sbjct: 148 TIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEG-RILARGEINFKDIQV 206
Query: 219 TVNYPPYISKAK---NTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRIENK 275
VN PP I + N ++GQ L C+A P W K+ ++ D +
Sbjct: 207 IVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFS 266
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
S LT V + D Y C+A NK G +A+I L
Sbjct: 267 DDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHL 302
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/195 (20%), Positives = 78/195 (40%), Gaps = 29/195 (14%)
Query: 51 ESATLRCTID-DRVTRVAWLNRSTILYAGNDKWS---------IDPRVIILVNTPTQYSI 100
E TL C D + + W ST + +K S +D +++ + S+
Sbjct: 323 EQVTLTCEASGDPIPSITW-RTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVS-SL 380
Query: 101 MIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAI 160
++++ D G Y C+ + ++L VQ P++ + T EG+ V + C
Sbjct: 381 TLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVF 439
Query: 161 GRPEPTVTWRHLSVKEGQGFVSED------------EYLEISDIKRDQSGEYECSALNDV 208
P T++W ++GQ S + YLE++ + G Y C+A+N +
Sbjct: 440 AYPSATISW----FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 495
Query: 209 AAPDVRKVKITVNYP 223
+ + + + P
Sbjct: 496 GQESLEFILVQADTP 510
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 234 VSVGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIE---NKGRMSTLTFFNVSEK 289
+SVG+ C+ A + WF T + RI N STLT +N +
Sbjct: 31 ISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTP-NQQRISVVWNDDSSSTLTIYNANID 89
Query: 290 DYGNYTCVATNKLGN 304
D G Y CV T + G+
Sbjct: 90 DAGIYKCVVTGEDGS 104
>gi|205277425 immunoglobulin superfamily, member 9 isoform a [Homo
sapiens]
Length = 1179
Score = 87.4 bits (215), Expect = 2e-17
Identities = 86/301 (28%), Positives = 126/301 (41%), Gaps = 30/301 (9%)
Query: 44 NVTVRQGESATLRCTIDDRVTR-----VAWLNRSTIL----YAGNDKWSIDPRVIILVNT 94
+V R GES L C + R + WL +L G IDP + V
Sbjct: 28 SVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRL 87
Query: 95 PTQYSIMIQNVDVYDEGPYTCSV-------QTDNHPKTSRVHLIVQVPPQIMNISSDIT- 146
S+ I+ + V D+G Y C V D+ S VHL V PPQ +
Sbjct: 88 QKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLE 147
Query: 147 VNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVS-EDEYLEISDIKRDQSGEYECS 203
V E VTL C+A G P P VTW R + +GQG V ++ L I ++R SG Y C
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQ 207
Query: 204 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM-AEFQWFKEETR 262
A + + + + P + KN+ V+ Q L+C A A P + WF++
Sbjct: 208 ASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267
Query: 263 LATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTCVATNKL---GNTNASITLYGPGA 316
+ R++ + R+ +L D G YTCV +N L + +A +T+ P
Sbjct: 268 V---FHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQ 324
Query: 317 V 317
V
Sbjct: 325 V 325
Score = 70.9 bits (172), Expect = 2e-12
Identities = 73/288 (25%), Positives = 111/288 (38%), Gaps = 28/288 (9%)
Query: 47 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
V++ E TLRC + V W R L G + + ++ I+ V
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-----------NGTLRIRRV 196
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP-E 164
+ G YTC + T L+V PP I+ + TVN V+L C A P
Sbjct: 197 ERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPAN 256
Query: 165 PTVTW-------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
T +W H+S + + + D L + + D +G Y C N + P
Sbjct: 257 LTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAY 316
Query: 218 ITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEF-QWFKEETRLATGLDGMRIENK 275
+TV YP + + T + +G G++ C A P F W K+ L LD ++
Sbjct: 317 LTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQ--LDKFPGWSQ 374
Query: 276 GRMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS----ITLYGPGAVID 319
G +L +E G Y+C N LG S + L P A I+
Sbjct: 375 GTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIE 422
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 82 WSIDPRVIILVNTP-----TQYSIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIV 132
W+ D + + L P T+ S++I + G Y+C S+ T +RV ++
Sbjct: 357 WTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRV--LL 414
Query: 133 QVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEIS 190
+ PP + + E G + + C A G P P V+W + +GQ V + L +
Sbjct: 415 KAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILR 474
Query: 191 DIKRDQSGEYECSALNDVA 209
+ ++ G +ECSA N VA
Sbjct: 475 PLTKEAHGHWECSASNAVA 493
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 87.0 bits (214), Expect = 2e-17
Identities = 98/324 (30%), Positives = 148/324 (45%), Gaps = 37/324 (11%)
Query: 14 LVVVSLRLLFLVPTGVP---VRSGDATFPKAMDNVTVRQGESATLRCTIDDRV-TRVAWL 69
+ V+ L L LVP V+ FP NVTV +G +A L C +D T + W
Sbjct: 1 MFVLFLCNLSLVPAAASKNKVKGSQGQFPLTQ-NVTVVEGGTAILTCRVDQNDNTSLQWS 59
Query: 70 NRST-ILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRV 128
N + LY + K D R+ ++ + + SI + +V + DEG YTCS+ T KTS+
Sbjct: 60 NPAQQTLYFDDKKALRDNRIELVRASWHELSISVSDVSLSDEGQYTCSLFT-MPVKTSKA 118
Query: 129 HL-IVQVP--PQIMNISSDITVNEGSSVTLLCLAIG-RPEPTVTW--RHLSVKEGQGFVS 182
+L ++ VP PQI SS V EG + L C G +P + W +K+ +
Sbjct: 119 YLTVLGVPEKPQISGFSS--PVMEGDLMQLTCKTSGSKPAADIRWFKNDKEIKDVKYLKE 176
Query: 183 ED---EYLEIS---DIKRDQSGE-------YECSALNDVAAPDVRKVKITVNYPPYISKA 229
ED + +S D + D+S + + +LN A P V + ++Y P +
Sbjct: 177 EDANRKTFTVSSTLDFRVDRSDDGVAVICRVDHESLN--ATPQVAMQVLEIHYTPSVKII 234
Query: 230 KNTGV-SVGQKGILSCEASAVPMAE-FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVS 287
+T GQ IL+CE+ P+ E W K+ L D R+ GR + F N
Sbjct: 235 PSTPFPQEGQPLILTCESKGKPLPEPVLWTKDGGELP---DPDRMVVSGRELNILFLN-- 289
Query: 288 EKDYGNYTCVATNKLGNTNASITL 311
+ D G Y C ATN +G ++A L
Sbjct: 290 KTDNGTYRCEATNTIGQSSAEYVL 313
Score = 32.7 bits (73), Expect = 0.49
Identities = 37/141 (26%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 94 TPTQYSIMIQNVDVYDEG-PYTCSVQTDNHPKTSRVH---LIVQVPPQIMNISSDITVNE 149
T T S + VD D+G C V ++ T +V L + P + I S E
Sbjct: 183 TFTVSSTLDFRVDRSDDGVAVICRVDHESLNATPQVAMQVLEIHYTPSVKIIPSTPFPQE 242
Query: 150 GSSVTLLCLAIGRPEPT-VTWRHLSVKEGQGFVSEDEY------LEISDIKRDQSGEYEC 202
G + L C + G+P P V W K+G D L I + + +G Y C
Sbjct: 243 GQPLILTCESKGKPLPEPVLW----TKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRC 298
Query: 203 SALNDVAAPDVRKVKITVNYP 223
A N + V I + P
Sbjct: 299 EATNTIGQSSAEYVLIVHDVP 319
>gi|205277423 immunoglobulin superfamily, member 9 isoform b [Homo
sapiens]
Length = 1163
Score = 86.7 bits (213), Expect = 3e-17
Identities = 82/283 (28%), Positives = 118/283 (41%), Gaps = 27/283 (9%)
Query: 44 NVTVRQGESATLRCTIDDRVTR-----VAWLNRSTIL----YAGNDKWSIDPRVIILVNT 94
+V R GES L C + R + WL +L G IDP + V
Sbjct: 28 SVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRL 87
Query: 95 PTQYSIMIQNVDVYDEGPYTCSV-------QTDNHPKTSRVHLIVQVPPQIMNISSDIT- 146
S+ I+ + V D+G Y C V D+ S VHL V PPQ +
Sbjct: 88 QKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLE 147
Query: 147 VNEGSSVTLLCLAIGRPEPTVTW--RHLSVKEGQGFVS-EDEYLEISDIKRDQSGEYECS 203
V E VTL C+A G P P VTW R + +GQG V ++ L I ++R SG Y C
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQ 207
Query: 204 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM-AEFQWFKEETR 262
A + + + + P + KN+ V+ Q L+C A A P + WF++
Sbjct: 208 ASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNIN 267
Query: 263 LATGLDGMRIENKGRM---STLTFFNVSEKDYGNYTCVATNKL 302
+ R++ + R+ +L D G YTCV +N L
Sbjct: 268 V---FHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGL 307
Score = 57.4 bits (137), Expect = 2e-08
Identities = 70/287 (24%), Positives = 104/287 (36%), Gaps = 42/287 (14%)
Query: 47 VRQGESATLRCTI-DDRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNV 105
V++ E TLRC + V W R L G + + ++ I+ V
Sbjct: 148 VQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQ-----------NGTLRIRRV 196
Query: 106 DVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRP-E 164
+ G YTC + T L+V PP I+ + TVN V+L C A P
Sbjct: 197 ERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPAN 256
Query: 165 PTVTW-------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVK 217
T +W H+S + + + D L + + D +G Y C N + P
Sbjct: 257 LTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAY 316
Query: 218 ITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEF-QWFKEETRLATGLDGMRIENKG 276
+TV P G++ C A P F W K+ L LD ++G
Sbjct: 317 LTVLCMP---------------GVIRCPVRANPPLLFVSWTKDGKALQ--LDKFPGWSQG 359
Query: 277 RMSTLTFFNVSEKDYGNYTCVATNKLGNTNAS----ITLYGPGAVID 319
+L +E G Y+C N LG S + L P A I+
Sbjct: 360 TEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIE 406
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 82 WSIDPRVIILVNTP-----TQYSIMIQNVDVYDEGPYTC----SVQTDNHPKTSRVHLIV 132
W+ D + + L P T+ S++I + G Y+C S+ T +RV ++
Sbjct: 341 WTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRV--LL 398
Query: 133 QVPPQIMNISSDITVNE-GSSVTLLCLAIGRPEPTVTWRHLSVK-EGQGFVSEDEYLEIS 190
+ PP + + E G + + C A G P P V+W + +GQ V + L +
Sbjct: 399 KAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILR 458
Query: 191 DIKRDQSGEYECSALNDVA 209
+ ++ G +ECSA N VA
Sbjct: 459 PLTKEAHGHWECSASNAVA 477
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 85.9 bits (211), Expect = 5e-17
Identities = 73/288 (25%), Positives = 114/288 (39%), Gaps = 40/288 (13%)
Query: 45 VTVRQGESATLRCTIDDRVTRV--AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
V+VR+G+ L C+ + +W+ + D R I T Y +
Sbjct: 205 VSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDS-----RRFISQETGNLYISKV 259
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----------------I 145
Q DV G Y C V K + + V PP + + +D +
Sbjct: 260 QTSDV---GSYICLV------KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 310
Query: 146 TVNEGSSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEISDIKRDQSGEYECS 203
T +G++V + C A+G P PT+TW ++ + LEI +++ D +G YEC
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECR 370
Query: 204 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 263
A N R YP ++ K +T + G C+A+ P ++W K L
Sbjct: 371 AENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL 430
Query: 264 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ R+E L NV++ D G Y C+A NK G AS L
Sbjct: 431 S---PQSRVEMVN--GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 473
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHP--KTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLL 156
+MI NV+ D G Y C + ++ + ++ P +N + I V + V +
Sbjct: 443 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 502
Query: 157 CLAIGRPEPTVTWR--HLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
C G P+PT++W+ +V+E + + D L I + + G+Y C N + ++
Sbjct: 503 CKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEI 562
Query: 214 RKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEA 246
++V P I K T ++VG+ +L+C+A
Sbjct: 563 -IASLSVKEPTRIELTPKRTELTVGESIVLNCKA 595
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/171 (23%), Positives = 62/171 (36%), Gaps = 17/171 (9%)
Query: 146 TVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY---------LEISDIKRDQ 196
T ++ V L C G P P+ W ++ G E +Y + + +
Sbjct: 112 TDSDEKKVALNCEVRGNPVPSYRW----LRNGTEIDLESDYRYSLIDGTFIISNPSEAKD 167
Query: 197 SGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV--GQKGILSCEASA-VPMAE 253
SG Y+C A N V + R+ + Y S + VSV GQ +L C P
Sbjct: 168 SGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEII 227
Query: 254 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
+ W E D R ++ L V D G+Y C+ N + N
Sbjct: 228 YSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKNTVTN 277
Score = 36.6 bits (83), Expect = 0.034
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 16/111 (14%)
Query: 203 SALNDVAAPDVRKVKITVNYPPYISKAKNTGV----SVGQKGILSCEASAVPMAEFQWFK 258
S +N + D K +V+Y P + + + S +K L+CE P+ ++W +
Sbjct: 78 SPINLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLR 137
Query: 259 EETRLATGLDGMRIENKGRMS----TLTFFNVSE-KDYGNYTCVATNKLGN 304
T + +E+ R S T N SE KD G+Y C+ATN +G+
Sbjct: 138 NGTEID-------LESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGS 181
Score = 28.5 bits (62), Expect = 9.2
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP 136
+MI+N+ + G Y C VQT + L+V+ PP
Sbjct: 635 LMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP 671
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 85.9 bits (211), Expect = 5e-17
Identities = 73/288 (25%), Positives = 114/288 (39%), Gaps = 40/288 (13%)
Query: 45 VTVRQGESATLRCTIDDRVTRV--AWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMI 102
V+VR+G+ L C+ + +W+ + D R I T Y +
Sbjct: 131 VSVREGQGVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDS-----RRFISQETGNLYISKV 185
Query: 103 QNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSD-----------------I 145
Q DV G Y C V K + + V PP + + +D +
Sbjct: 186 QTSDV---GSYICLV------KNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 236
Query: 146 TVNEGSSVTLLCLAIGRPEPTVTWRHLS--VKEGQGFVSEDEYLEISDIKRDQSGEYECS 203
T +G++V + C A+G P PT+TW ++ + LEI +++ D +G YEC
Sbjct: 237 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECR 296
Query: 204 ALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRL 263
A N R YP ++ K +T + G C+A+ P ++W K L
Sbjct: 297 AENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL 356
Query: 264 ATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ R+E L NV++ D G Y C+A NK G AS L
Sbjct: 357 S---PQSRVEMVN--GVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL 399
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/154 (24%), Positives = 72/154 (46%), Gaps = 8/154 (5%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHP--KTSRVHLIVQVPPQIMN-ISSDITVNEGSSVTLL 156
+MI NV+ D G Y C + ++ + ++ P +N + I V + V +
Sbjct: 369 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIE 428
Query: 157 CLAIGRPEPTVTWR--HLSVKEGQGF-VSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
C G P+PT++W+ +V+E + + D L I + + G+Y C N + ++
Sbjct: 429 CKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEI 488
Query: 214 RKVKITVNYPPYIS-KAKNTGVSVGQKGILSCEA 246
++V P I K T ++VG+ +L+C+A
Sbjct: 489 -IASLSVKEPTRIELTPKRTELTVGESIVLNCKA 521
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/171 (23%), Positives = 62/171 (36%), Gaps = 17/171 (9%)
Query: 146 TVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEY---------LEISDIKRDQ 196
T ++ V L C G P P+ W ++ G E +Y + + +
Sbjct: 38 TDSDEKKVALNCEVRGNPVPSYRW----LRNGTEIDLESDYRYSLIDGTFIISNPSEAKD 93
Query: 197 SGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSV--GQKGILSCEASA-VPMAE 253
SG Y+C A N V + R+ + Y S + VSV GQ +L C P
Sbjct: 94 SGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEII 153
Query: 254 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGN 304
+ W E D R ++ L V D G+Y C+ N + N
Sbjct: 154 YSWVFNEFPSFVAEDSRRFISQ-ETGNLYISKVQTSDVGSYICLVKNTVTN 203
Score = 28.5 bits (62), Expect = 9.2
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 100 IMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP 136
+MI+N+ + G Y C VQT + L+V+ PP
Sbjct: 561 LMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP 597
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 85.1 bits (209), Expect = 8e-17
Identities = 82/298 (27%), Positives = 118/298 (39%), Gaps = 43/298 (14%)
Query: 37 TFPKAMDNVTVRQGESATLRCTID-DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTP 95
TF + N V + E+ RC + D V W L G +
Sbjct: 242 TFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGR------------YDIK 289
Query: 96 TQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTL 155
Y++ I+ DEG Y C + + L V+ PPQ + D V +G +VT
Sbjct: 290 DDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTF 349
Query: 156 LCLAIGRPEPTVTWRHLSVKEG---------------QGFVSEDEYLEISDIKRDQSGEY 200
C G P+P V W+ KEG + VS L I++I+R +G Y
Sbjct: 350 PCETKGNPQPAVFWQ----KEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYY 405
Query: 201 ECSALNDVAAPDVRKVKITV------NYPPYISKA-KNTGVSVGQKGILSCEASAVPMAE 253
C AL VA + K ++ V PP I + N ++V +L C+A+ P+
Sbjct: 406 ICQALT-VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPV 464
Query: 254 FQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
W KE I+ +G TL N+ D G YTCVAT+ G T+ S L
Sbjct: 465 ISWLKEGFTFPGRDPRATIQEQG---TLQIKNLRISDTGTYTCVATSSSGETSWSAVL 519
Score = 65.5 bits (158), Expect = 7e-11
Identities = 68/279 (24%), Positives = 110/279 (39%), Gaps = 20/279 (7%)
Query: 44 NVTVRQGESATLRCTIDDRVT-RVAWLNRSTILYAGNDKWSIDPRVI-ILVNTPTQYSIM 101
+V V +GE TL C + R T + W + D DPR +L+ + + + +
Sbjct: 55 DVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKD----DPRSHRMLLPSGSLFFLR 110
Query: 102 IQNV--DVYDEGPYTCSVQTDNHPKTSRVHL--IVQVPPQIMNISSDITVNEGSSVTLLC 157
I + DEG Y C + SR + + +D+ V G L C
Sbjct: 111 IVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILEC 170
Query: 158 LAI-GRPEPTVTWRHLSVK---EGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDV 213
G PEPT+ W+ V+ + + L IS+ ++ +G Y C N V D
Sbjct: 171 QPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDS 230
Query: 214 RKVKITV-NYPPYISKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEETRLATGLDGMRI 272
++TV P ++ + N V + C+ P +W K++ L G ++
Sbjct: 231 DPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKD 290
Query: 273 ENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 311
+ TL D G Y C+A N++G AS TL
Sbjct: 291 D-----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL 324
Score = 62.4 bits (150), Expect = 6e-10
Identities = 51/193 (26%), Positives = 81/193 (41%), Gaps = 28/193 (14%)
Query: 135 PPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDE--------- 185
PP+I+ SD+ V++G TL C A GRP PT+ W K+G+ ++ +
Sbjct: 46 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEW----YKDGERVETDKDDPRSHRMLL 101
Query: 186 ------YLEISDIKRDQ--SGEYECSALNDVAAPDVRKVKITVNY--PPYISKAKNTGVS 235
+L I +R + G Y C A N + R + V + + V+
Sbjct: 102 PSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVA 161
Query: 236 VGQKGILSCE-ASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNY 294
G+ IL C+ P W K++ R+ + + I R L N + D G Y
Sbjct: 162 AGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI----RGGKLMISNTRKSDAGMY 217
Query: 295 TCVATNKLGNTNA 307
TCV TN +G ++
Sbjct: 218 TCVGTNMVGERDS 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,293,511
Number of Sequences: 37866
Number of extensions: 556035
Number of successful extensions: 5364
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 1501
Number of HSP's gapped (non-prelim): 2092
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.